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Sample records for nonrepetitive runout nrro

  1. Nonrepetitive Colouring via Entropy Compression

    CERN Document Server

    Dujmović, Vida; Wood, David R

    2011-01-01

    A vertex colouring of a graph is \\emph{nonrepetitive} if there is no path whose first half receives the same sequence of colours as the second half. A graph is nonrepetitively $k$-choosable if given lists of at least $k$ colours at each vertex, there is a nonrepetitive colouring such that each vertex is coloured from its own list. It is known that every graph with maximum degree $\\Delta$ is $c\\Delta^2$-choosable, for some constant $c$. We prove this result with $c=4$. We then prove that every subdivision of a graph with sufficiently many division vertices per edge is nonrepetitively 6-choosable. The proofs of both these results are based on the Moser-Tardos entropy-compression method, and a recent extension by Grytczuk, Kozik and Micek for the nonrepetitive choosability of paths. Finally, we prove that every graph with pathwidth $k$ is nonrepetitively ($2k^2+6k+1$)-colourable.

  2. Nonrepetitive Colourings of Planar Graphs with $O(\\log n)$ Colours

    CERN Document Server

    Dujmović, Vida; Joret, Gwenaël; Wood, David R

    2012-01-01

    A vertex colouring of a graph is \\emph{nonrepetitive} if there is no path for which the first half of the path is assigned the same sequence of colours as the second half. The \\emph{nonrepetitive chromatic number} of a graph $G$ is the minimum integer $k$ such that $G$ has a nonrepetitive $k$-colouring. Whether planar graphs have bounded nonrepetitive chromatic number is one of the most important open problems in the field. Despite this, the best known upper bound is $O(\\sqrt{n})$ for $n$-vertex planar graphs. We prove a $O(\\log n)$ upper bound.

  3. Numerical modeling of the debris flows runout

    Science.gov (United States)

    Federico, Francesco; Cesali, Chiara

    2017-06-01

    Rapid debris flows are identified among the most dangerous of all landslides. Due to their destructive potential, the runout length has to be predicted to define the hazardous areas and design safeguarding measures. To this purpose, a continuum model to predict the debris flows mobility is developed. It is based on the well known depth-integrated avalanche model proposed by Savage and Hutter (S&H model) to simulate the dry granular materials flows. Conservation of mass and momentum equations, describing the evolving geometry and the depth averaged velocity distribution, are re-written taking into account the effects of the interstitial pressures and the possible variation of mass along the motion due to erosion/deposition processes. Furthermore, the mechanical behaviour of the debris flow is described by a recently developed rheological law, which allows to take into account the dissipative effects of the grain inelastic collisions and friction, simultaneously acting within a `shear layer', typically at the base of the debris flows. The governing PDEs are solved by applying the finite difference method. The analysis of a documented case is finally carried out.

  4. Long runout landslides: a solution from granular mechanics

    Directory of Open Access Journals (Sweden)

    Stanislav eParez

    2015-10-01

    Full Text Available Large landslides exhibit surprisingly long runout distances compared to a rigid body sliding from the same slope, and the mechanism of this phenomena has been studied for decades. This paper shows that the observed long runouts can be explained quite simply via a granular pile flowing downhill, while collapsing and spreading, without the need for frictional weakening that has traditionally been suggested to cause long runouts. Kinematics of the granular flow is divided into center of mass motion and spreading due to flattening of the flowing mass. We solve the center of mass motion analytically based on a frictional law valid for granular flow, and find that center of mass runout is similar to that of a rigid body. Based on the shape of deposits observed in experiments with collapsing granular columns and numerical simulations of landslides, we derive a spreading length Rf~V^1/3. Spreading of a granular pile, leading to a deposit angle much lower than the angle of repose or the dynamic friction angle, is shown to be an important, often dominating, contribution to the total runout distance, accounting for the long runouts observed for natural landslides.

  5. Accurate Runout Measurement for HDD Spinning Motors and Disks

    Science.gov (United States)

    Jiang, Quan; Bi, Chao; Lin, Song

    As hard disk drive (HDD) areal density increases, its track width becomes smaller and smaller and so is non-repeatable runout. HDD industry needs more accurate and better resolution runout measurements of spinning spindle motors and media platters in both axial and radial directions. This paper introduces a new system how to precisely measure the runout of HDD spinning disks and motors through synchronously acquiring the rotor position signal and the displacements in axial or radial directions. In order to minimize the synchronizing error between the rotor position and the displacement signal, a high resolution counter is adopted instead of the conventional phase-lock loop method. With Laser Doppler Vibrometer and proper signal processing, the proposed runout system can precisely measure the runout of the HDD spinning disks and motors with 1 nm resolution and 0.2% accuracy with a proper sampling rate. It can provide an effective and accurate means to measure the runout of high areal density HDDs, in particular the next generation HDDs, such as, pattern media HDDs and HAMR HDDs.

  6. Long runout landslides: a solution from granular mechanics

    Science.gov (United States)

    Parez, Stanislav; Aharonov, Einat

    2015-10-01

    Large landslides exhibit surprisingly long runout distances compared to a rigid body sliding from the same slope, and the mechanism of this phenomena has been studied for decades. This paper shows that the observed long runouts can be explained quite simply via a granular pile flowing downhill, while collapsing and spreading, without the need for frictional weakening that has traditionally been suggested to cause long runouts. Kinematics of the granular flow is divided into center of mass motion and spreading due to flattening of the flowing mass. We solve the center of mass motion analytically based on a frictional law valid for granular flow, and find that center of mass runout is similar to that of a rigid body. Based on the shape of deposits observed in experiments with collapsing granular columns and numerical simulations of landslides, we derive a spreading length Rf~V^1/3. Spreading of a granular pile, leading to a deposit angle much lower than the angle of repose or the dynamic friction angle, is shown to be an important, often dominating, contribution to the total runout distance, accounting for the long runouts observed for natural landslides.

  7. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

    NARCIS (Netherlands)

    J.M.C. Tubio (Jose M.); Y. Li (Yilong); Y.S. Ju (Young Seok); I. Martincorena (Inigo); S.L. Cooke (Susanna); M. Tojo (Marta); G. Gundem (Gunes); C.P. Pipinikas (Christodoulos); J. Zamora (Jorge); J.W. Raine (John); D. Menzies; P. Roman-Garcia (Pablo); A. Fullam (Anthony); M. Gerstung (Moritz); A. Shlien (Adam); P.S. Tarpey (Patrick); E. Papaemmanuil (Elli); S. Knappskog (Stian); P. van Loo (Peter); M. Ramakrishna (Manasa); H. Davies (Helen); J. Marshall (John); D.C. Wedge (David); J. Teague (Jon); A. Butler (Adam); S. Nik-Zainal (Serena); L.B. Alexandrov (Ludmil); S. Behjati (Sam); L.R. Yates (Lucy); N. Bolli (Niccolò); L. Mudie (Laura); C. Hardy (Claire); S. Martin (Sandra); S. McLaren (Stuart); S. O'Meara (Sarah); E. Anderson (Elizabeth); M. Maddison (Mark); S. Gamble (Stephen); C. Foster (Christopher); A.Y. Warren (Anne); H.J. Whitaker (Heather); D. Brewer (Daniel); R. Eeles (Rosalind); C. Cooper (Colin); D. Neal (David); A.G. Lynch (Andy); T. Visakorpi (Tapio); W.B. Isaacs (William); L.J. van 't Veer (Laura); C. Caldas (Carlos); C. Desmedt (Christine); C. Sotiriou (Christos); S. Aparicio (Sam); J.A. Foekens (John); J. Eyfjord; S. Lakhani (Sunil); G. Thomas (Gilles); O. Myklebost (Ola); P.N. Span (Paul); A.L. Børresen-Dale (Anne Lise); A.L. Richardson (Andrea); M.J. Vijver (Marc ); A. Vincent-Salomon (Anne); G.G. van den Eynden (Gert); A.M. Flanagan (Adrienne); P.A. Futreal (Andrew); H. Janes (Holly); G.S. Bova (G. Steven); M.R. Stratton (Michael); U. McDermott (Ultan); P.J. Campbell (Peter)

    2014-01-01

    textabstractLong interspersed nuclear element–1 (L1) retrotransposons are mobile repetitive elements that are abundant in the human genome. L1 elements propagate through RNA intermediates. In the germ line, neighboring, nonrepetitive sequences are occasionally mobilized by the L1 machinery, a proces

  8. Effects of debris flow composition on runout, depositional mechanisms, and deposit morphology in laboratory experiments

    NARCIS (Netherlands)

    de Haas, Tjalling; Braat, Lisanne; Leuven, Jasper R F W; Lokhorst, Ivar R.; Kleinhans, Maarten G.

    2015-01-01

    Predicting debris flow runout is of major importance for hazard mitigation. Apart from topography and volume, runout distance and area depends on debris flow composition and rheology, but how is poorly understood. We experimentally investigated effects of composition on debris flow runout, depositio

  9. Biosynthesis and characterization of a non-repetitive polypeptide derived from silk fibroin heavy chain

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Gaoqiang; Wu, Mingyang; Yi, Honggen; Wang, Jiannan, E-mail: wangjn@suda.edu.cn

    2016-02-01

    Silk fibroin heavy chain is the major protein component of Bombyx mori silk fibroin and is composed of 12 repetitive and 11 non-repetitive regions, with the non-repetitive domain consisting of a hydrophilic polypeptide chain. In order to determine the biomedical function of the non-repetitive domain or potentially use it to modify hydrophobic biomaterials, high-purity isolation is necessary. Previously, we cloned and extended a gene motif (f(1)) encoding the non-repetitive domain. Here, this motif and its multimers are inserted into a glutathione S-transferase (GST)-tagged fusion-protein expression vector. Motif f(1) and multimers f(4) and f(8) were expressed in Escherichia coli BL21 cells following isopropyl β-D-1-thiogalactopyranoside induction, purified by GST-affinity chromatography, and single bands of purified fusion proteins GST-F(1), GST-F(4), and GST-F(8), were visualized by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Target polypeptides F(1), F(4), and F(8), were cleaved clearly from the GST-fusion tag following thrombin digestion. Mass spectrometry results indicate that the molecular weights associated with fusion proteins GST-F(1), GST-F(4), and GST-F(8) are 31.5, 43.8, and 59.0 kDa, respectively, and with the cleaved polypeptides F(1), F(4), and F(8) are 4.8, 16.8, and 32.8 kDa, respectively. The F(1), F(4), and F(8) polypeptide chains are negatively charged with isoelectric points (pI) of 3.3, 3.2, and 3.0, respectively. The molecular weight and pI values of the polypeptide chains are consistent with the predicted values and the amino acid compositions similar to predicted sequences. FTIR and CD results show the molecular conformation of F(1) was mainly random coil, and more stable α-helix structure formed in longer molecular chain. - Highlights: • A non-repetitive domain and its multimers of silk fibroin were expressed by E. coli. • The corresponding target polypeptides F(1), F(4) and F(8) were cleaved clearly. • Their

  10. Assessing the debris flow run-out frequency of a catchment in the French Alps using a parameterization analysis with the RAMMS numerical run-out model

    NARCIS (Netherlands)

    Hussin, Y.A.; Quan Luna, B.; Van Westen, C.J.; Christen, M.; Malet, J.P.; Asch, Th.W.J. van

    2012-01-01

    Debris flows occurring in the European Alps frequently cause significant damage to settlements, power-lines and transportation infrastructure which has led to traffic disruptions, economic loss and even death. Estimating the debris flow run-out extent and the parameter uncertainty related to run-out

  11. Unravelling the multiphase run-out conditions of a slide-flow mass movement

    Science.gov (United States)

    van Asch, Th. W. J.; Xu, Q.; Dong, X. J.

    2015-02-01

    In this paper an attempt is made to unravel the run-out characteristics of a mass movement in the Sichuan Province, SW China by means of 1D numerical modelling and calibration on the topography of run-out profiles. The Dagou mass movement started as a rockslide with an initial volume of 480,000 m3, which transformed into a debris flow, increasing in volume due to entrainment of loose material in the upper part of the travelling track. The rapid mass movement had a run-out distance of 1380 m and a run-out time of about 50 s. Numerical calculations were conducted with the depth average shallow water equation to explain the variation in thickness of the debris flow deposits along the run-out track. For the calibration of the first run-out phase, three rheological models were applied, namely the Bingham, Voellmy and Quadratic rheology. Calibration was done on 1) the run-out distance, 2) the run-out time and 3) the goodness of fit with the thickness of the deposits along the track. In addition the erosion constant in the entrainment equation was calibrated on the observed versus calculated run-out volumes. Sensitivity analyses of the resistance parameters for the different rheologies showed that the viscosity, the basal friction, the turbulence term and the resistance factor are the most sensitive ones. It appeared that the variation in thickness along the run-out track can be explained by entrainment of material in the upper part of the track and a change in parametric values during the run-out process. The three rheologies produced a reasonable fit with the observed geometry of the run-out profile, run-out time and run-out volume. It was argued that the Voellmy rheology seems to give the most appropriate explanation for the difference in resistance along the run-out path. The main problem in the simulation was to stop the debris flow on a slope with a gradient around 22°. A reactivation of the mass movement by frictional sliding of the material half way the run-out

  12. Debris-flow runout predictions based on the average channel slope (ACS)

    Science.gov (United States)

    Prochaska, A.B.; Santi, P.M.; Higgins, J.D.; Cannon, S.H.

    2008-01-01

    Prediction of the runout distance of a debris flow is an important element in the delineation of potentially hazardous areas on alluvial fans and for the siting of mitigation structures. Existing runout estimation methods rely on input parameters that are often difficult to estimate, including volume, velocity, and frictional factors. In order to provide a simple method for preliminary estimates of debris-flow runout distances, we developed a model that provides runout predictions based on the average channel slope (ACS model) for non-volcanic debris flows that emanate from confined channels and deposit on well-defined alluvial fans. This model was developed from 20 debris-flow events in the western United States and British Columbia. Based on a runout estimation method developed for snow avalanches, this model predicts debris-flow runout as an angle of reach from a fixed point in the drainage channel to the end of the runout zone. The best fixed point was found to be the mid-point elevation of the drainage channel, measured from the apex of the alluvial fan to the top of the drainage basin. Predicted runout lengths were more consistent than those obtained from existing angle-of-reach estimation methods. Results of the model compared well with those of laboratory flume tests performed using the same range of channel slopes. The robustness of this model was tested by applying it to three debris-flow events not used in its development: predicted runout ranged from 82 to 131% of the actual runout for these three events. Prediction interval multipliers were also developed so that the user may calculate predicted runout within specified confidence limits. ?? 2008 Elsevier B.V. All rights reserved.

  13. Fixed parameter algorithms for restricted coloring problems: acyclic, star, nonrepetitive, harmonious and clique colorings

    CERN Document Server

    Campos, Victor; Maia, Ana Karolinna; Martins, Nicolas; Sampaio, Rudini Menezes

    2011-01-01

    In this paper, we obtain polynomial time algorithms to determine the acyclic chromatic number, the star chromatic number, the Thue chromatic number, the harmonious chromatic number and the clique chromatic number of $P_4$-tidy graphs and $(q,q-4)$-graphs, for every fixed $q$. These classes include cographs, $P_4$-sparse and $P_4$-lite graphs. All these coloring problems are known to be NP-hard for general graphs. These algorithms are fixed parameter tractable on the parameter $q(G)$, which is the minimum $q$ such that $G$ is a $(q,q-4)$-graph. We also prove that every connected $(q,q-4)$-graph with at least $q$ vertices is 2-clique-colorable and that every acyclic coloring of a cograph is also nonrepetitive.

  14. Unravelling the multiphase run-out conditions of a slide- flow mass movement

    NARCIS (Netherlands)

    van Asch, Theo; Xu, Qiang; Dong, X.J.

    2014-01-01

    In this paper an attempt is made to unravel the run-out characteristics of a mass movement in the Sichuan Province, SW China by means of 1D numerical modelling and calibration on the topography of run-out profiles.The Dagou mass movement started as a rockslide with an initial volume of 480,000m3, wh

  15. A new optical disk driver fine-seek algorithm based on runout learning

    Science.gov (United States)

    Chen, Cheng-Hung; Yen, Jia-Yush

    2005-01-01

    The eccentricity in the Optical Disk Drive (ODD) is the inevitable deviation of the geometric center of circular tracks from the rotating center of the disk. The resulted "runout" in the drive is thus periodic with disk rotation. To overcome the runout, conventional approach is for the pick-up head to go forward to the target track while shaking with the period runout during track accessing. This paper proposes an integration of the learning algorithm to learn the runout motion with an on-line observer to estimate the track runout during track accessing. The purpose is to allow for online computation of the target track kinematics so that the controller can adjust the accessing strategy to accommodate for the target track behavior. The proposed algorithm is demonstrated to be feasible through experiments applied to the fine jump control for a general optical storage opto-mechenical-electrical-control plant from OES in ITRI.

  16. Application of Cooling Water in Controlled Runout Table Cooling on Hot Strip Mill

    Institute of Scientific and Technical Information of China (English)

    LIU Zheng-dong; I V Samarasekera

    2004-01-01

    The controlled runout table cooling is essential in determining the final mechanical properties and flatness of steel strip. The heat of a hot steel strip is mainly extracted by cooling water during runout. In order to study the heat transfer by water jet impingement boiling during runout, a pilot facility was constructed at the University of British Columbia. On this pilot facility, the water jet impingement tests were carried out under various cooling conditions to investigate the effect of processing parameters, such as cooling water temperature, water jet impingement velocity, initial strip temperature, water flow rate, water nozzle diameter and array of water nozzles, on the heat transfer of heated strip. The results obtained contribute to the optimization of cooling water during runout.

  17. Coupling of rainfall-induced landslide triggering model with predictions of debris flow runout distances

    Science.gov (United States)

    Lehmann, Peter; von Ruette, Jonas; Fan, Linfeng; Or, Dani

    2014-05-01

    Rapid debris flows initiated by rainfall induced shallow landslides present a highly destructive natural hazard in steep terrain. The impact and run-out paths of debris flows depend on the volume, composition and initiation zone of released material and are requirements to make accurate debris flow predictions and hazard maps. For that purpose we couple the mechanistic 'Catchment-scale Hydro-mechanical Landslide Triggering (CHLT)' model to compute timing, location, and landslide volume with simple approaches to estimate debris flow runout distances. The runout models were tested using two landslide inventories obtained in the Swiss Alps following prolonged rainfall events. The predicted runout distances were in good agreement with observations, confirming the utility of such simple models for landscape scale estimates. In a next step debris flow paths were computed for landslides predicted with the CHLT model for a certain range of soil properties to explore its effect on runout distances. This combined approach offers a more complete spatial picture of shallow landslide and subsequent debris flow hazards. The additional information provided by CHLT model concerning location, shape, soil type and water content of the released mass may also be incorporated into more advanced models of runout to improve predictability and impact of such abruptly-released mass.

  18. Damage tolerance optimization of composite stringer run-out under tensile load

    DEFF Research Database (Denmark)

    Badalló, Pere; Trias, Daniel; Lindgaard, Esben

    2015-01-01

    and Genetic Algorithms. In the solution process, the RBF were used to compute the objective function: ratio between the energy release rate and the critical energy release rate according to the Benzeggagh–Kenane mixed mode criterion. Some design guidelines to obtain a damage tolerant stringer-panel interface....... The influence of some geometric variables of the run-out in the interface of the set stringer-panel is crucial to avoid the onset and growth of delamination cracks. In this study, a damage tolerant design of a stringer run-out is achieved by a process of design optimization and surrogate modeling techniques....... A parametric finite element model created with python was used to generate a number of different geometrical designs of the stringer run-out. The relevant information of these models was adjusted using Radial Basis Functions (RBF). Finally, the optimization problem was solved using Quasi-Newton method...

  19. PATH: a work sampling-based approach to ergonomic job analysis for construction and other non-repetitive work.

    Science.gov (United States)

    Buchholz, B; Paquet, V; Punnett, L; Lee, D; Moir, S

    1996-06-01

    A high prevalence and incidence of work-related musculoskeletal disorders have been reported in construction work. Unlike industrial production-line activity, construction work, as well as work in many other occupations (e.g. agriculture, mining), is non-repetitive in nature; job tasks are non-cyclic, or consist of long or irregular cycles. PATH (Posture, Activity, Tools and Handling), a work sampling-based approach, was developed to characterize the ergonomic hazards of construction and other non-repetitive work. The posture codes in the PATH method are based on the Ovako Work Posture Analysing System (OWAS), with other codes included for describing worker activity, tool use, loads handled and grasp type. For heavy highway construction, observations are stratified by construction stage and operation, using a taxonomy developed specifically for this purpose. Observers can code the physical characteristics of the job reliably after about 30 h of training. A pilot study of six construction laborers during four road construction operations suggests that laborers spend large proportions of time in nonneutral trunk postures and spend approximately 20% of their time performing manual material handling tasks. These results demonstrate how the PATH method can be used to identify specific construction operations and tasks that are ergonomically hazardous.

  20. Simulation of accelerated strip cooling on the hot rolling mill run-out roller table

    Directory of Open Access Journals (Sweden)

    E.Makarov

    2016-07-01

    Full Text Available A mathematical model of the thermal state of the metal in the run-out roller table continuous wide hot strip mill. The mathematical model takes into account heat generation due to the polymorphic γ → α transformation of supercooled austenite phase state and the influence of the chemical composition of the steel on the physical properties of the metal. The model allows calculation of modes of accelerated cooling strips on run-out roller table continuous wide hot strip mill. Winding temperature calculation error does not exceed 20°C for 98.5 % of strips of low-carbon and low-alloy steels

  1. Dynamics, velocity and run-out of the giant Storegga slide

    Science.gov (United States)

    de Blasio, F.; Issler, D.; Elverhøi, A.; Harbitz, C. B.; Ilstad, T.; Bryn, P.; Lien, R.; Løvholt, F.

    2003-04-01

    A huge slide (volume of 2400 km^3 and run-out 450 km) was released in the Storegga area off the western coast of Norway during early Holocene, followed by numerous smaller debris flows. We perform numerical simulations of the giant slide using a Bingham model for the clay material. Agreement with present deposit distribution and run-out is found by assuming that the shear resistance between the debris flow and the seabed decreases during the flow, and we suggest sediment remolding or hydroplaning as possible explanations. Debris velocities are predicted and possible applications to the associated tsunami event are investigated.

  2. Linking rainfall-induced landslides with debris flows runout patterns towards catchment scale hazard assessment

    Science.gov (United States)

    Fan, Linfeng; Lehmann, Peter; McArdell, Brian; Or, Dani

    2017-03-01

    Debris flows and landslides induced by heavy rainfall represent an ubiquitous and destructive natural hazard in steep mountainous regions. For debris flows initiated by shallow landslides, the prediction of the resulting pathways and associated hazard is often hindered by uncertainty in determining initiation locations, volumes and mechanical state of the mobilized debris (and by model parameterization). We propose a framework for linking a simplified physically-based debris flow runout model with a novel Landslide Hydro-mechanical Triggering (LHT) model to obtain a coupled landslide-debris flow susceptibility and hazard assessment. We first compared the simplified debris flow model of Perla (1980) with a state-of-the art continuum-based model (RAMMS) and with an empirical model of Rickenmann (1999) at the catchment scale. The results indicate that predicted runout distances by the Perla model are in reasonable agreement with inventory measurements and with the other models. Predictions of localized shallow landslides by LHT model provides information on water content of released mass. To incorporate effects of water content and flow viscosity as provided by LHT on debris flow runout, we adapted the Perla model. The proposed integral link between landslide triggering susceptibility quantified by LHT and subsequent debris flow runout hazard calculation using the adapted Perla model provides a spatially and temporally resolved framework for real-time hazard assessment at the catchment scale or along critical infrastructure (roads, railroad lines).

  3. Comparison of runout range of PDCs in different density using Volcflow numerical simulation model

    Science.gov (United States)

    Chang, C.; Yun, S. H.

    2016-12-01

    In our preceding research, we simulated 45 scenarios using of a VolcFlow numerical simulation model to calculate runout range of pyroclastic density currents that caused by column collapse of the explosive Plinian eruption on the Mt. Baekdu, Korean peninsula (the border of North Korea and China). We assumed 2,000 kg/m3 for density of PDCs in previous scenarios. In this study, in order to find out the change of the runout range that according to different density, we refer to study of Rowley(2010), about the scale of density of PDCs that is 500- 3,000 kg/m3. So we set the density of the PDCs as 1,000 kg/m3, 2,000 kg/m3, 3,000 kg/m3, respectively under the same condition in previous study. Then we simulated total of 15 scenarios from VEI 3 to VEI 7 and compared to the results. In the results, the runout range of PDCs are increased a little in higher density. It seems that dense currents have high kinetic energy that makes the range of PDCs higher. But there are not a big differences in runout ranges even in case of VEI 7. Therefore, the density of PDCs does not have much effect on the runout range of PDCs. In this study we assumed the column collapse caused the PDCs, it needs further research in another type of PDCs that occurred by lava dome collapse.This research was supported by a grant [MPSS-NH-2015-81] through the Disaster and Safety Management Institute funded by Ministry of Public Safety and Security of Korean government.

  4. Adaptive ILC algorithms of nonlinear continuous systems with non-parametric uncertainties for non-repetitive trajectory tracking

    Science.gov (United States)

    Li, Xiao-Dong; Lv, Mang-Mang; Ho, John K. L.

    2016-07-01

    In this article, two adaptive iterative learning control (ILC) algorithms are presented for nonlinear continuous systems with non-parametric uncertainties. Unlike general ILC techniques, the proposed adaptive ILC algorithms allow that both the initial error at each iteration and the reference trajectory are iteration-varying in the ILC process, and can achieve non-repetitive trajectory tracking beyond a small initial time interval. Compared to the neural network or fuzzy system-based adaptive ILC schemes and the classical ILC methods, in which the number of iterative variables is generally larger than or equal to the number of control inputs, the first adaptive ILC algorithm proposed in this paper uses just two iterative variables, while the second even uses a single iterative variable provided that some bound information on system dynamics is known. As a result, the memory space in real-time ILC implementations is greatly reduced.

  5. Nano-level instrumentation for analyzing the dynamic accuracy of a rolling element bearing

    Science.gov (United States)

    Yang, Z.; Hong, J.; Zhang, J.; Wang, M. Y.; Zhu, Y.

    2013-12-01

    The rotational performance of high-precision rolling bearings is fundamental to the overall accuracy of complex mechanical systems. A nano-level instrument to analyze rotational accuracy of high-precision bearings of machine tools under working conditions was developed. In this instrument, a high-precision (error motion spindle was applied to spin the test bearing. Operating conditions could be simulated effectively because of the large axial loading capacity. An air-cylinder, controlled by a proportional pressure regulator, was applied to drive an air-bearing subjected to non-contact and precise loaded axial forces. The measurement results on axial loading and rotation constraint with five remaining degrees of freedom were completely unconstrained and uninfluenced by the instrument's structure. Dual capacity displacement sensors with 10 nm resolution were applied to measure the error motion of the spindle using a double-probe error separation method. This enabled the separation of the spindle's error motion from the measurement results of the test bearing which were measured using two orthogonal laser displacement sensors with 5 nm resolution. Finally, a Lissajous figure was used to evaluate the non-repetitive run-out (NRRO) of the bearing at different axial forces and speeds. The measurement results at various axial loadings and speeds showed the standard deviations of the measurements' repeatability and accuracy were less than 1% and 2%. Future studies will analyze the relationship between geometrical errors and NRRO, such as the ball diameter differences of and the geometrical errors in the grooves of rings.

  6. A high-precision instrument for analyzing nonlinear dynamic behavior of bearing cage

    Science.gov (United States)

    Yang, Z.; Chen, H.; Yu, T.; Li, B.

    2016-08-01

    The high-precision ball bearing is fundamental to the performance of complex mechanical systems. As the speed increases, the cage behavior becomes a key factor in influencing the bearing performance, especially life and reliability. This paper develops a high-precision instrument for analyzing nonlinear dynamic behavior of the bearing cage. The trajectory of the rotational center and non-repetitive run-out (NRRO) of the cage are used to evaluate the instability of cage motion. This instrument applied an aerostatic spindle to support and spin test the bearing to decrease the influence of system error. Then, a high-speed camera is used to capture images when the bearing works at high speeds. A 3D trajectory tracking software tema Motion is used to track the spot which marked the cage surface. Finally, by developing the matlab program, a Lissajous' figure was used to evaluate the nonlinear dynamic behavior of the cage with different speeds. The trajectory of rotational center and NRRO of the cage with various speeds are analyzed. The results can be used to predict the initial failure and optimize cage structural parameters. In addition, the repeatability precision of instrument is also validated. In the future, the motorized spindle will be applied to increase testing speed and image processing algorithms will be developed to analyze the trajectory of the cage.

  7. A high-precision instrument for analyzing nonlinear dynamic behavior of bearing cage.

    Science.gov (United States)

    Yang, Z; Chen, H; Yu, T; Li, B

    2016-08-01

    The high-precision ball bearing is fundamental to the performance of complex mechanical systems. As the speed increases, the cage behavior becomes a key factor in influencing the bearing performance, especially life and reliability. This paper develops a high-precision instrument for analyzing nonlinear dynamic behavior of the bearing cage. The trajectory of the rotational center and non-repetitive run-out (NRRO) of the cage are used to evaluate the instability of cage motion. This instrument applied an aerostatic spindle to support and spin test the bearing to decrease the influence of system error. Then, a high-speed camera is used to capture images when the bearing works at high speeds. A 3D trajectory tracking software tema Motion is used to track the spot which marked the cage surface. Finally, by developing the matlab program, a Lissajous' figure was used to evaluate the nonlinear dynamic behavior of the cage with different speeds. The trajectory of rotational center and NRRO of the cage with various speeds are analyzed. The results can be used to predict the initial failure and optimize cage structural parameters. In addition, the repeatability precision of instrument is also validated. In the future, the motorized spindle will be applied to increase testing speed and image processing algorithms will be developed to analyze the trajectory of the cage.

  8. Rock avalanche deposits store quantitative evidence on internal shear during runout

    Science.gov (United States)

    Zhang, M.; McSaveney, M. J.

    2017-09-01

    We investigated the quantitative effect of internal shear on grain breakage during rock avalanche runout, by means of 38 ring-shear experiments on identical sand samples at different normal stresses, shear strains and shear strain rates. We compared sample grain-size characteristics before and after shearing. We found that grain size decreased with increase in normal stress and shear strain. Reduction in grain size was inferred to occur through grain breakage associated with grain interactions in strong force chains during strain. The results were consistent with observations of both inverse-grading structure in deep rock avalanche exposures, and fining and grading of particles with increasing rock avalanche travel distance. Our study suggested that with appropriate calibration, variations in grain-size distributions within a rock avalanche deposit would provide quantitative information on the distribution of internal shear during its runout.

  9. Collapse dynamics and runout of dense granular materials in a fluid.

    Science.gov (United States)

    Topin, V; Monerie, Y; Perales, F; Radjaï, F

    2012-11-02

    We investigate the effect of an ambient fluid on the dynamics of collapse and spread of a granular column simulated by means of the contact dynamics method interfaced with computational fluid dynamics. The runout distance is found to increase as a power law with the aspect ratio of the column, and, surprisingly, for a given aspect ratio and packing fraction, it may be similar in the grain-inertial and fluid-inertial regimes but with considerably longer duration in the latter case. We show that the effect of fluid in viscous and fluid-inertial regimes is to both reduce the kinetic energy during collapse and enhance the flow by lubrication during spread. Hence, the runout distance in a fluid may be below or equal to that in the absence of fluid due to compensation between those effects.

  10. Probabilistic landslide run-out assessment with a 2-D dynamic numerical model using a Monte Carlo method

    Science.gov (United States)

    Cepeda, Jose; Luna, Byron Quan; Nadim, Farrokh

    2013-04-01

    An essential component of a quantitative landslide hazard assessment is establishing the extent of the endangered area. This task requires accurate prediction of the run-out behaviour of a landslide, which includes the estimation of the run-out distance, run-out width, velocities, pressures, and depth of the moving mass and the final configuration of the deposits. One approach to run-out modelling is to reproduce accurately the dynamics of the propagation processes. A number of dynamic numerical models are able to compute the movement of the flow over irregular topographic terrains (3-D) controlled by a complex interaction between mechanical properties that may vary in space and time. Given the number of unknown parameters and the fact that most of the rheological parameters cannot be measured in the laboratory or field, the parametrization of run-out models is very difficult in practice. For this reason, the application of run-out models is mostly used for back-analysis of past events and very few studies have attempted to achieve forward predictions. Consequently all models are based on simplified descriptions that attempt to reproduce the general features of the failed mass motion through the use of parameters (mostly controlling shear stresses at the base of the moving mass) which account for aspects not explicitly described or oversimplified. The uncertainties involved in the run-out process have to be approached in a stochastic manner. It is of significant importance to develop methods for quantifying and properly handling the uncertainties in dynamic run-out models, in order to allow a more comprehensive approach to quantitative risk assessment. A method was developed to compute the variation in run-out intensities by using a dynamic run-out model (MassMov2D) and a probabilistic framework based on a Monte Carlo simulation in order to analyze the effect of the uncertainty of input parameters. The probability density functions of the rheological parameters

  11. Transport and emplacement mechanisms of channelised long-runout debris avalanches, Ruapehu volcano, New Zealand

    Science.gov (United States)

    Tost, M.; Cronin, S. J.; Procter, J. N.

    2014-12-01

    The steep flanks of composite volcanoes are prone to collapse, producing debris avalanches that completely reshape the landscape. This study describes new insights into the runout of large debris avalanches enhanced by topography, using the example of six debris avalanche deposits from Mount Ruapehu, New Zealand. Individual large flank collapses (>1 km3) produced all of these units, with four not previously recognised. Five major valleys within the highly dissected landscape surrounding Mount Ruapehu channelled the debris avalanches into deep gorges (≥15 m) and resulted in extremely long debris avalanche runouts of up to 80 km from source. Classical sedimentary features of debris avalanche deposits preserved in these units include the following: very poor sorting with a clay-sand matrix hosting large subrounded boulders up to 5 m in diameter, jigsaw-fractured clasts, deformed clasts and numerous rip-up clasts of late-Pliocene marine sediments. The unusually long runouts led to unique features in distal deposits, including a pervasive and consolidated interclast matrix, and common rip-up clasts of Tertiary mudstone, as well as fluvial gravels and boulders. The great travel distances can be explained by the debris avalanches entering deep confined channels (≥15 m), where friction was minimised by a reduced basal contact area along with loading of water-saturated substrates which formed a basal lubrication zone for the overlying flowing mass. Extremely long-runout debris avalanches are most likely to occur in settings where initially partly saturated collapsing masses move down deep valleys and become thoroughly liquified at their base. This happens when pore water is available within the base of the flowing mass or in the sediments immediately below it. Based on their H/L ratio, confined volcanic debris avalanches are two to three times longer than unconfined, spreading flows of similar volume. The hybrid qualities of the deposits, which have some similarities to

  12. Source characteristics of long runout rock avalanches triggered by the 2008 Wenchuan earthquake, China

    Science.gov (United States)

    Qi, Shengwen; Xu, Qiang; Zhang, Bing; Zhou, Yuande; Lan, Hengxing; Li, Lihui

    2011-03-01

    The May 12, 2008 Wenchuan, China Earthquake which measured M w = 8.3 according to Chinese Earthquake Administration - CEA ( M w = 7.9 according to the USGS) directly triggered many landslides, which caused about 20,000 deaths, a quarter of the total. Rock avalanches were among the most destructive landslides triggered by this seismic event, and have killed more people than any other type of landslide in this earthquake. The Donghekou rock avalanche, one example of a catastrophic avalanche triggered by the Wenchuan earthquake, occurred in Qingchuan and buried one primary school and 184 houses, resulting in more than 780 deaths, and in addition, caused the formation of two landslide dams, which formed barrier lakes. Combining aerial images (resolution of 0.5 m) with field investigations, this paper lists some parameters of 66 cases in one table, and details source characteristics of six typical cases. It has been found that most of the long runout rock avalanches have source areas with high relief and steep inclination, causing the debris in the travel courses to accelerate. There was also a large amount of saturated Holocene-age loose deposits formed by a river or gully that existed in the travel courses. Comparison studies indicate that saturated Holocene loose deposits in the travel courses could be the most important factor for the causes of the long runout characteristic of the rock avalanches especially when they traveled over gentle or even flat ground surfaces. Furthermore, the relationships among the relief slope gradient, runout and covered area are investigated, and a threshold line for predicting the maximum horizontal runout distance under certain change in elevation is presented.

  13. Numerical modeling of debris flow runout for a case in southwestern China with Smooth Particle Hydrodynamics

    Science.gov (United States)

    Braun, Anika; Cuomo, Sabatino; Wang, Xueliang; Zhang, Luqing

    2016-04-01

    Debris flows and landslide dams are a major natural hazard causing high socioeconomic risk in inhabited mountainous areas. This is also true for vast parts of southwestern China, which are highly prone to slope failures due to several factors, such as a humid climate with high precipitation in the summer months, geological predisposing factors with highly weathered sedimentary rocks and a high seismicity. Not only do the landslides and flooding related to landslide dams threaten residents, buildings and transportation structures, but also do flooding conditions endanger power supply, which relies in this region partly on hydropower. In order to assess the potential of landslides to block rivers, it is crucial to understand which factors influence possible run-out distances and how they can be quantified. In the study we are presenting a numerical modeling analysis for a particular case of a complex landslide in Ningnan county, southwestern China, which transformed into a debris flow and blocked the river and the major road leading through the valley after heavy rainfall. For this purpose a quasi-3D Smooth Particle Hydrodynamics (SPH) model was implemented that can account for geotechnical slope parameters, run-out distance, velocities and deposition heights. A digital terrain model and the geometry information of the landslide were used as input data in order to estimate the relevant geotechnical parameters by back-analysis. The results of the analysis can be used for the prediction of run-out distances for future events at this site and other similar sites.

  14. Reply to comment by Iverson on "The reduction of friction in long runout landslides as an emergent phenomenon"

    Science.gov (United States)

    Johnson, Brandon C.; Campbell, Charles S.; Melosh, H. Jay

    2016-11-01

    Here we address the comments by Iverson (2016) on our recent work concerning the reduction of friction in long runout landslides. Iverson (2016) questions the veracity of our models and suggests that high basal pore fluid pressure is the dominant mechanism reducing friction in long runout landslides. The main goal of our work was to elucidate the mechanism responsible for the apparent reduction of friction and long runout occurring in the landslide simulations of Campbell et al. (1995), which did not include an interstitial fluid. We found that the apparent reduction of friction in large slides could be explained by acoustic waves causing sliding to preferentially occur at pressures below the expected overburden, a mechanism reminiscent of acoustic fluidization. Such a mechanism is required to explain the long runout of dry landslides such as those on the Moon and other airless or waterless bodies. While our models provide no estimates of the effect of fluids on landslide runout, we have demonstrated a mechanism that increases runout distances that does not involve fluids.

  15. Self-sustaining non-repetitive activity in a large scale neuronal-level model of the hippocampal circuit.

    Science.gov (United States)

    Scorcioni, Ruggero; Hamilton, David J; Ascoli, Giorgio A

    2008-10-01

    The mammalian hippocampus is involved in spatial representation and memory storage and retrieval, and much research is ongoing to elucidate the cellular and system-level mechanisms underlying these cognitive functions. Modeling may be useful to link network-level activity patterns to the relevant features of hippocampal anatomy and electrophysiology. Investigating the effects of circuit connectivity requires simulations of a number of neurons close to real scale. To this end, we construct a model of the hippocampus with 16 distinct neuronal classes (including both local and projection cells) and 200,000 individual neurons. The number of neurons in each class and their interconnectivity are drawn from rat anatomy. Here we analyze the emergent network activity and how it is affected by reducing either the size or the connectivity diversity of the model. When the model is run with a simple variation of the McCulloch-Pitts formalism, self-sustaining non-repetitive activity patterns consistently emerge. Specific firing threshold values are narrowly constrained for each cell class upon multiple runs with different stochastic wiring and initial conditions, yet these values do not directly affect network stability. Analysis of the model at different network sizes demonstrates that a scale reduction of one order of magnitude drastically alters network dynamics, including the variability of the output range, the distribution of firing frequencies, and the duration of self-sustained activity. Moreover, comparing the model to a control condition with an equivalent number of (excitatory/inhibitory balanced) synapses, but removing all class-specific information (i.e. collapsing the network to homogeneous random connectivity) has surprisingly similar effects to downsizing the total number of neurons. The reduced-scale model is also compared directly with integrate-and-fire simulations, which capture considerably more physiological detail at the single-cell level, but still fail

  16. Structure of the exceptionally large nonrepetitive carbohydrate backbone of the lipopolysaccharide of Pectinatus frisingensis strain VTT E-82164.

    Science.gov (United States)

    Vinogradov, Evgeny; Petersen, Bent O; Sadovskaya, Irina; Jabbouri, Said; Duus, Jens Ø; Helander, Ilkka M

    2003-07-01

    The structures of the oligosaccharides obtained after acetic acid hydrolysis and alkaline deacylation of the rough-type lipopolysaccharide (LPS) from Pectinatus frisingensis strain VTT E-82164 were analysed using NMR spectroscopy, MS and chemical methods. The LPS contains two major structural variants, differing by a decasaccharide fragment, and some minor variants lacking the terminal glucose residue. The largest structure of the carbohydrate backbone of the LPS that could be deduced from experimental results consists of 25 monosaccharides (including the previously found Ara4NP residue in lipid A) arranged in a well-defined nonrepetitive structure: We presume that the shorter variant with R1 = H represents the core-lipid A part of the LPS, and the additional fragment is present instead of the O-specific polysaccharide. Structures of this type have not been previously described. Analysis of the deacylation products obtained from the LPS of the smooth strain, VTT E-79100T, showed that it contains a very similar core but with one different glycosidic linkage.

  17. AschFlow - A dynamic landslide run-out model for medium scale hazard analysis.

    Science.gov (United States)

    Luna, Byron Quan; Blahut, Jan; van Asch, Theo; van Westen, Cees; Kappes, Melanie

    2015-04-01

    Landslides and debris flow hazard assessments require a scale-dependent analysis in order to mitigate damage and other negative consequences at the respective scales of occurrence. Medium or large scale landslide run-out modelling for many possible landslide initiation areas has been a cumbersome task in the past. This arises from the difficulty to precisely define the location and volume of the released mass and from the inability of the run-out models to compute the displacement with a large amount of individual initiation areas (computational exhaustive). Most of the existing physically based run-out models have complications in handling such situations and therefore empirical methods have been used as a practical mean to predict landslides mobility at a medium scale (1:10,000 to 1:50,000). In this context, a simple medium scale numerical model for rapid mass movements in urban and mountainous areas was developed. The deterministic nature of the approach makes it possible to calculate the velocity, height and increase in mass by erosion, resulting in the estimation of various forms of impacts exerted by debris flows at the medium scale The established and implemented model ("AschFlow") is a 2-D one-phase continuum model that simulates, the entrainment, spreading and deposition process of a landslide or debris flow at a medium scale. The flow is thus treated as a single phase material, whose behavior is controlled by rheology (e.g. Voellmy or Bingham). The developed regional model "AschFlow" was applied and evaluated in well documented areas with known past debris flow events.

  18. Major risk from rapid, large-volume landslides in Europe (EU Project RUNOUT)

    Science.gov (United States)

    Kilburn, Christopher R. J.; Pasuto, Alessandro

    2003-08-01

    Project RUNOUT has investigated methods for reducing the risk from large-volume landslides in Europe, especially those involving rapid rates of emplacement. Using field data from five test sites (Bad Goisern and Köfels in Austria, Tessina and Vajont in Italy, and the Barranco de Tirajana in Gran Canaria, Spain), the studies have developed (1) techniques for applying geomorphological investigations and optical remote sensing to map landslides and their evolution; (2) analytical, numerical, and cellular automata models for the emplacement of sturzstroms and debris flows; (3) a brittle-failure model for forecasting catastrophic slope failure; (4) new strategies for integrating large-area Global Positioning System (GPS) arrays with local geodetic monitoring networks; (5) methods for raising public awareness of landslide hazards; and (6) Geographic Information System (GIS)-based databases for the test areas. The results highlight the importance of multidisciplinary studies of landslide hazards, combining subjects as diverse as geology and geomorphology, remote sensing, geodesy, fluid dynamics, and social profiling. They have also identified key goals for an improved understanding of the physical processes that govern landslide collapse and runout, as well as for designing strategies for raising public awareness of landslide hazards and for implementing appropriate land management policies for reducing landslide risk.

  19. Assessing potential debris flow runout: a comparison of two simulation models

    Directory of Open Access Journals (Sweden)

    M. Pirulli

    2008-08-01

    Full Text Available In the present paper some of the problems related to the application of the continuum mechanics modelling to debris flow runout simulation are discussed.
    Particularly, a procedure is proposed to face the uncertainties in the choice of a numerical code and in the setting of rheological parameter values that arise when the prediction of a debris flow propagation is required.
    In this frame, the two codes RASH3D and FLO2D are used to numerically analyse the propagation of potential debris flows affecting two study sites in Southern Italy.
    For these two study sites, a lack in information prevents that the rheological parameters can be obtained from the back analysis of similar well documented debris flow events in the area. As a prediction of the possible runout area is however required by decision makers, an alternative approach based on the analysis of the alluvial fans existing at the toe of the two studied basins is proposed to calibrate rheological parameters on the safe side.
    From the comparison of the results obtained with RASH3D (where a Voellmy and a Quadratic rheologies are implemented and FLO2D (where a Quadratic rheology is implemented it emerges that, for the two examined cases, numerical analyses carried out with RASH3D assuming a Voellmy rheology can be considered on the safe side respect to those carried out with a Quadratic rheology.

  20. Magnitude estimation and runout analysis of a rockslide for the construction of a defensive structure

    Science.gov (United States)

    Gigli, G.; Casagli, N.; Lombardi, L.; Nocentini, M.; Balducci, M.; Venanti, L.

    2009-04-01

    In the past few years the Maiolica (micritic limestone) quarry of Torgiovannetto (Perugia, Italy) has suffered an increasing amount of rockfalls. The rock mass has loosened progressively and a perimetral crack longer than 100 meters has appeared. The huge block bounded by this crack, two lateral discontinuities and a stratigraphic layer, threatens two roads at the base of the slope. Since these are very important and busy traffic routes the Department of Earth Sciences of the University of Firenze performed magnitude estimations and runout analyses regarding two different aspects: 1) investigate the trajectories of single falling blocks and; 2) forecast the runout distance and the debris intensity distribution in case a large rockslide occurs. The magnitude of a landslide is, actually, the most important input parameter for correctly estimating the trajectory, the runout distance and the kinetic energy of a landslide. A detailed and updated knowledge of the actual morphological conditions is a good starting point for defining as accurately as possible the extent of a moving block. Due to the very high urgency and precision required, a detailed survey of the quarry area has been performed by means of a High Accuracy & Long Range 3D laser scanner (RIEGLE, LMS-Z.420i). In order to avoid shadow zones and to obtain a comprehensive digital elevation model of the quarry area, a total of more than 30 million points were taken from three different scan positions. The resulting point cloud was dense enough to reveal the main structural features of the rock mass, including the discontinuities bounding the moving block, which has a calculated volume of 180 000 m3. With the aim of confirming the block volume and assessing the deformational field of the moving mass, a multitemporal ground-based interferometric SAR survey was performed. The results of the survey precisely confirm the geometry of the unstable block and also indicate that the displacements decrease from E to W, due

  1. An integrated model to assess critical rain fall thresholds for the critical run-out distances of debris flows

    NARCIS (Netherlands)

    van Asch, Th.W.J.; Tang, C.; Alkema, D.; Zhu, J.; Zhou, W.

    2013-01-01

    A dramatic increase in debris flows occurred in the years after the 2008 Wenchuan earthquake in SW China due to the deposition of loose co-seismic landslide material. This paper proposes a preliminary integrated model, which describes the relationship between rain input and debris flow run-out in or

  2. Study on Runout Volume and Runout Zones of Rainstorm and Channelized Debris Flows%暴雨沟谷型泥石流冲出量和冲出范围研究

    Institute of Scientific and Technical Information of China (English)

    方群生; 张卫旭; 夏晨皓; 王帅永; 杨涛; 刘鑫磊

    2016-01-01

    不同类型泥石流一次性冲出量和冲出范围的影响因子和权重存在差异。“5·12”汶川地震后,震区沟谷流域内的大量松散物质在强降雨作用下形成了很多规模较大的降雨型泥石流,选取汶川震区20条暴雨沟谷型泥石流沟,对其被一次降雨过程的一次性冲出量、最大冲出长度、最大冲出宽度的预测方法进行了研究,应用多元统计方法建立了泥石流一次性冲出量和冲出范围预测模型。结果表明:影响泥石流一次性冲出量和冲出范围的因素除了总物源量、动储量总量、流域面积、沟道纵向长度、相对高差等自然因素外,还有筑坝、矿产开采、泥石流流域内边坡开挖等人为因素;所建立的模型适用于汶川震区暴雨沟谷型泥石流一次性冲出量和冲出范围的预测。%It is quite different that the influence factors and weights vary of different kinds of a one⁃time runout volume and runout zones of rainstorm and channelized debris flows. Rainstorm⁃induced debris flows were remobilized from large amounts of loose material triggered by Wenchuan earthquake. This paper selected the 20 rainstorms and channelized debris flows which had an entire alluvial fans and a single type as a typical case. And researched a one⁃time runout volume and the maximum runout distance and depositional width of rainstorm and channelized debris flows after a one⁃time rainfall. Applying the multivariate regression analysis, a mathematical model was established to estimate a one⁃time runout volume and the maximum runout distance and depositional width. The validation shows that affecting a one⁃time runout volume and runout zones of rainstorm and channelized debris flows is not only including the total amount of material source, dynamic reserve, drainage area, the longitudinal length of the channel and relative height difference of natural factor, but also damming, minerals exploitation and

  3. Towards a numerical run-out model for quick-clay slides

    Science.gov (United States)

    Issler, Dieter; L'Heureux, Jean-Sébastien; Cepeda, José M.; Luna, Byron Quan; Gebreslassie, Tesfahunegn A.

    2015-04-01

    Highly sensitive glacio-marine clays occur in many relatively low-lying areas near the coasts of eastern Canada, Scandinavia and northern Russia. If the load exceeds the yield stress of these clays, they quickly liquefy, with a reduction of the yield strength and the viscosity by several orders of magnitude. Leaching, fluvial erosion, earthquakes and man-made overloads, by themselves or combined, are the most frequent triggers of quick-clay slides, which are hard to predict and can attain catastrophic dimensions. The present contribution reports on two preparatory studies that were conducted with a view to creating a run-out model tailored to the characteristics of quick-clay slides. One study analyzed the connections between the morphological and geotechnical properties of more than 30 well-documented Norwegian quick-clay slides and their run-out behavior. The laboratory experiments by Locat and Demers (1988) suggest that the behavior of quick clays can be reasonably described by universal relations involving the liquidity index, plastic index, remolding energy, salinity and sensitivity. However, these tests should be repeated with Norwegian clays and analyzed in terms of a (shear-thinning) Herschel-Bulkley fluid rather than a Bingham fluid because the shear stress appears to grow in a sub-linear fashion with the shear rate. Further study is required to understand the discrepancy between the material parameters obtained in laboratory tests of material from observed slides and in back-calculations of the same slides with the simple model by Edgers & Karlsrud (1982). The second study assessed the capability of existing numerical flow models to capture the most important aspects of quick-clay slides by back-calculating three different, well documented events in Norway: Rissa (1978), Finneidfjord (1996) and Byneset (2012). The numerical codes were (i) BING, a quasi-two-dimensional visco-plastic model, (ii) DAN3D (2009 version), and (iii) MassMov2D. The latter two are

  4. Long runout mechanism of recent earthquake-triggered landslides in Japan and China

    Science.gov (United States)

    Fukuoka, Hiroshi; Wang, Gonghui; Miyagi, Toyohiko; Cui, Peng; Igwe, Ogbonnaya; Georgieva, Ekaterina

    2010-05-01

    1. Rapid, long runout mechanism on horizontal sliding surface The 2008 Iwate-Miyagi Nairiku Earthquake, Japan of Ms 7.2 caused uncountable landslides in the epicenter area. Largest was the Aratozawa Dam Landslide and its volume is estimated as 70 million cubic meters. It ran rapidly for about 300 m in less than 5 minutes on almost horizontal (1 - 2 degrees) sliding surface. Authors sampled weathered pumice and sand/siltstone from surface of the landslide toe part for ring shear tests and obtained following results; (1) The cyclic loading ring shear test on weathered pumice using observed earthquake main shock acceleration waveform showed limited residual shear displacement. (2) Repeated undrained cyclic loading ring shear tests on saturated siltstone sample finally showed unlimited shear displacement behavior even though the shear stress was as small as about 5 degrees (3) Undrained monotonic loading ring shear test on same pumice proved that the steady state strength is only 30 kPa for shear displacement larger than about 100 mm. Because the steady-state strength is independent of initial normal stress, smallest apparent friction angle of 1 - 2 degrees can be expected. 2. Long runout mechanism of limestone detachment type landslide Many limestone detachment-type landslides have been triggered by the gigantic 2008 Wenchuan Earthquake, China. The Chaping landslides is the largest one and blocked the downslope river to create temporal reservoir, which was, then removed by the army. Authors sampled the landslide debris of crashed limestone near the toe part and conducted ring shear test. The specimen was fully saturated and sheared under undrained condition and constant-shear-speed condition to obtain the long-distance shear behavior. Stress path reached failure at peak friction angle of 41.8 degrees and then went down along the failure line until shear displacement reached about 100 mm. The stress condition stayed the ultimate steady state thereafter. This stress

  5. Modelling wet snow avalanche runout to assess road safety at a high-altitude mine in the central Andes

    Science.gov (United States)

    Valero, Cesar Vera; Wever, Nander; Bühler, Yves; Stoffel, Lukas; Margreth, Stefan; Bartelt, Perry

    2016-11-01

    Mining activities in cold regions are vulnerable to snow avalanches. Unlike operational facilities, which can be constructed in secure locations outside the reach of avalanches, access roads are often susceptible to being cut, leading to mine closures and significant financial losses. In this paper we discuss the application of avalanche runout modelling to predict the operational risk to mining roads, a long-standing problem for mines in high-altitude, snowy regions. We study the 35 km long road located in the "Cajón del rio Blanco" valley in the central Andes, which is operated by the Codelco Andina copper mine. In winter and early spring, this road is threatened by over 100 avalanche paths. If the release and snow cover conditions can be accurately specified, we find that avalanche dynamics modelling is able to represent runout, and safe traffic zones can be identified. We apply a detailed, physics-based snow cover model to calculate snow temperature, density and moisture content in three-dimensional terrain. This information is used to determine the initial and boundary conditions of the avalanche dynamics model. Of particular importance is the assessment of the current snow conditions along the avalanche tracks, which define the mass and thermal energy entrainment rates and therefore the possibility of avalanche growth and long runout distances.

  6. Nano-level instrumentation for analyzing the dynamic accuracy of a rolling element bearing

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Z.; Hong, J.; Zhang, J.; Wang, M. Y. [State Key Laboratory for Manufacturing Systems Engineering, Xi' an Jiaotong University, Xi' an (China); Zhu, Y. [Key Laboratory of Education Ministry for Modern Design and Rotor-Bearing System, Xi' an Jiaotong University, Xi' an (China)

    2013-12-15

    The rotational performance of high-precision rolling bearings is fundamental to the overall accuracy of complex mechanical systems. A nano-level instrument to analyze rotational accuracy of high-precision bearings of machine tools under working conditions was developed. In this instrument, a high-precision (error motion < 0.15 μm) and high-stiffness (2600 N axial loading capacity) aerostatic spindle was applied to spin the test bearing. Operating conditions could be simulated effectively because of the large axial loading capacity. An air-cylinder, controlled by a proportional pressure regulator, was applied to drive an air-bearing subjected to non-contact and precise loaded axial forces. The measurement results on axial loading and rotation constraint with five remaining degrees of freedom were completely unconstrained and uninfluenced by the instrument's structure. Dual capacity displacement sensors with 10 nm resolution were applied to measure the error motion of the spindle using a double-probe error separation method. This enabled the separation of the spindle's error motion from the measurement results of the test bearing which were measured using two orthogonal laser displacement sensors with 5 nm resolution. Finally, a Lissajous figure was used to evaluate the non-repetitive run-out (NRRO) of the bearing at different axial forces and speeds. The measurement results at various axial loadings and speeds showed the standard deviations of the measurements’ repeatability and accuracy were less than 1% and 2%. Future studies will analyze the relationship between geometrical errors and NRRO, such as the ball diameter differences of and the geometrical errors in the grooves of rings.

  7. Influence of check dams on debris-flow run-out intensity

    Directory of Open Access Journals (Sweden)

    A. Remaître

    2008-12-01

    Full Text Available Debris flows are very dangerous phenomena claiming thousands of lives and millions of Euros each year over the world. Disaster mitigation includes non-structural (hazard mapping, insurance policies, active structural (drainage systems and passive structural (check dams, stilling basins countermeasures. Since over twenty years, many efforts are devoted by the scientific and engineering communities to the design of proper devices able to capture the debris-flow volume and/or break down the energy. If considerable theoretical and numerical work has been performed on the size, the shape and structure of check dams, allowing the definition of general design criteria, it is worth noting that less research has focused on the optimal location of these dams along the debris-flow pathway.

    In this paper, a methodological framework is proposed to evaluate the influence of the number and the location of the check dams on the reduction of the debris-flow intensity (in term of flow thickness, flow velocity and volume. A debris-flow model is used to simulate the run-out of the debris flow. The model uses the Janbu force diagram to resolve the force equilibrium equations; a bingham fluid rheology is introduced and represents the resistance term. The model has been calibrated on two muddy debris-flow events that occurred in 1996 and 2003 at the Faucon watershed (South French Alps.

    Influence of the check dams on the debris-flow intensity is quantified taking into account several check dams configurations (number and location as input geometrical parameters. Results indicate that debris-flow intensity is decreasing with the distance between the source area and the first check dams. The study demonstrates that a small number of check dams located near the source area may decrease substantially the debris-flow intensity on the alluvial fans.

  8. GIS-based debris flow source and runout susceptibility assessment from DEM data - a case study in NW Nicaragua

    Science.gov (United States)

    Guinau, M.; Vilajosana, I.; Vilaplana, J. M.

    2007-11-01

    In October 1998, Hurricane Mitch triggered numerous landslides (mainly debris flows) in Honduras and Nicaragua, resulting in a high death toll and in considerable damage to property. The potential application of relatively simple and affordable spatial prediction models for landslide hazard mapping in developing countries was studied. Our attention was focused on a region in NW Nicaragua, one of the most severely hit places during the Mitch event. A landslide map was obtained at 1:10 000 scale in a Geographic Information System (GIS) environment from the interpretation of aerial photographs and detailed field work. In this map the terrain failure zones were distinguished from the areas within the reach of the mobilized materials. A Digital Elevation Model (DEM) with 20 m×20 m of pixel size was also employed in the study area. A comparative analysis of the terrain failures caused by Hurricane Mitch and a selection of 4 terrain factors extracted from the DEM which, contributed to the terrain instability, was carried out. Land propensity to failure was determined with the aid of a bivariate analysis and GIS tools in a terrain failure susceptibility map. In order to estimate the areas that could be affected by the path or deposition of the mobilized materials, we considered the fact that under intense rainfall events debris flows tend to travel long distances following the maximum slope and merging with the drainage network. Using the TauDEM extension for ArcGIS software we generated automatically flow lines following the maximum slope in the DEM starting from the areas prone to failure in the terrain failure susceptibility map. The areas crossed by the flow lines from each terrain failure susceptibility class correspond to the runout susceptibility classes represented in a runout susceptibility map. The study of terrain failure and runout susceptibility enabled us to obtain a spatial prediction for landslides, which could contribute to landslide risk mitigation.

  9. GIS-based debris flow source and runout susceptibility assessment from DEM data – a case study in NW Nicaragua

    Directory of Open Access Journals (Sweden)

    J. M. Vilaplana

    2007-11-01

    Full Text Available In October 1998, Hurricane Mitch triggered numerous landslides (mainly debris flows in Honduras and Nicaragua, resulting in a high death toll and in considerable damage to property. The potential application of relatively simple and affordable spatial prediction models for landslide hazard mapping in developing countries was studied. Our attention was focused on a region in NW Nicaragua, one of the most severely hit places during the Mitch event. A landslide map was obtained at 1:10 000 scale in a Geographic Information System (GIS environment from the interpretation of aerial photographs and detailed field work. In this map the terrain failure zones were distinguished from the areas within the reach of the mobilized materials. A Digital Elevation Model (DEM with 20 m×20 m of pixel size was also employed in the study area. A comparative analysis of the terrain failures caused by Hurricane Mitch and a selection of 4 terrain factors extracted from the DEM which, contributed to the terrain instability, was carried out. Land propensity to failure was determined with the aid of a bivariate analysis and GIS tools in a terrain failure susceptibility map. In order to estimate the areas that could be affected by the path or deposition of the mobilized materials, we considered the fact that under intense rainfall events debris flows tend to travel long distances following the maximum slope and merging with the drainage network. Using the TauDEM extension for ArcGIS software we generated automatically flow lines following the maximum slope in the DEM starting from the areas prone to failure in the terrain failure susceptibility map. The areas crossed by the flow lines from each terrain failure susceptibility class correspond to the runout susceptibility classes represented in a runout susceptibility map. The study of terrain failure and runout susceptibility enabled us to obtain a spatial prediction for landslides, which could contribute to landslide risk

  10. r.massmov: a GRASS GIS module for landslide runout assessment in early warning monitoring systems

    Science.gov (United States)

    Cannata, Massimiliano; Molinari, Monia; Meisina, Claudia

    2013-04-01

    In the last decades, early warning systems have become a precious support in hazard management by helping in reducing the possible damages caused by natural and anthropic hazards. Furthermore, in the last years, thanks to the rapid advances in science and technology a new concept of innovative early warning systems has been developed taking advantage of the decreasing costs of sensors and the wide diffusion and coverage of internet services (WFS, WMS, WPS, SOS, etc.). In this concept, simulation models can play an important role: in fact, by allowing the objective assessment of the location and intensity of a possible disaster, they can provide valuable information to support decision makers in taking timely and appropriate disaster responses. r.massmov is a new GRASS GIS module for landslide runout simulation over complex topographies developed to meet the expectation of innovative early warning systems modeling services, identified by the authors through four key requirements: i) low simulation times, ii) geospatial capabilities, iii) three-dimensional analysis and iv) open source approach. The model, based on the combined use of shallow water equations and rheological formulas, is the result of a series of enhancements to the original Massmov2D code (Begueria et al. 2009) to significantly improve algorithms and computational times. With this work the authors want to illustrate the main characteristics of r.massmov model: the governing equations, the input/output data, the algorithms and the results of the model application on a case study located in Tessin (Switzerland) that highlighted the effectiveness of the changes performed to the original code in terms of time performances. Furthermore, the authors want to present a set of GRASS GIS specific tools for r.massmov (r.massmov.sensitivity, r.massmov.calibration, r.ucode), developed to systematize and simplify model sensitivity analysis and calibration procedures. References: Begueria S, Van Asch T W J, Malet J

  11. Quantitative assessment of changes in landslide risk using a regional scale run-out model

    Science.gov (United States)

    Hussin, Haydar; Chen, Lixia; Ciurean, Roxana; van Westen, Cees; Reichenbach, Paola; Sterlacchini, Simone

    2015-04-01

    The risk of landslide hazard continuously changes in time and space and is rarely a static or constant phenomena in an affected area. However one of the main challenges of quantitatively assessing changes in landslide risk is the availability of multi-temporal data for the different components of risk. Furthermore, a truly "quantitative" landslide risk analysis requires the modeling of the landslide intensity (e.g. flow depth, velocities or impact pressures) affecting the elements at risk. Such a quantitative approach is often lacking in medium to regional scale studies in the scientific literature or is left out altogether. In this research we modelled the temporal and spatial changes of debris flow risk in a narrow alpine valley in the North Eastern Italian Alps. The debris flow inventory from 1996 to 2011 and multi-temporal digital elevation models (DEMs) were used to assess the susceptibility of debris flow triggering areas and to simulate debris flow run-out using the Flow-R regional scale model. In order to determine debris flow intensities, we used a linear relationship that was found between back calibrated physically based Flo-2D simulations (local scale models of five debris flows from 2003) and the probability values of the Flow-R software. This gave us the possibility to assign flow depth to a total of 10 separate classes on a regional scale. Debris flow vulnerability curves from the literature and one curve specifically for our case study area were used to determine the damage for different material and building types associated with the elements at risk. The building values were obtained from the Italian Revenue Agency (Agenzia delle Entrate) and were classified per cadastral zone according to the Real Estate Observatory data (Osservatorio del Mercato Immobiliare, Agenzia Entrate - OMI). The minimum and maximum market value for each building was obtained by multiplying the corresponding land-use value (€/msq) with building area and number of floors

  12. CONVERGENCE ANALYSIS IN SENSE OF LEBESGUE-p NORM OF DECENTRALIZED NON-REPETITIVE ITERATIVE LEARNING CONTROL FOR LINEAR LARGE-SCALE SYSTEMS

    Institute of Scientific and Technical Information of China (English)

    Xiaoe RUAN; Huizhuo WU; Na LI; Baiwu WAN

    2009-01-01

    In this paper, a decentralized iterative learning control strategy is embedded into the procedure of hierarchical steady-state optimization for a class of linear large-scale industrial processes which consists of a number of subsystems. The task of the learning controller for each subsystem is to iteratively generate a sequence of upgraded control inputs to take responsibilities of a sequential step functional control signals with distinct scales which are determined by the local decision-making units in the two-layer hierarchical steady-state optimization processing. The objective of the designated strategy is to consecutively improve the transient performance of the system. By means of the generalized Young inequality of convolution integral, the convergence of the learning algorithm is analyzed in the sense of Lebesgue-p norm. It is shown that the inherent feature of system such as the multi-dimensionality and the interaction may influence the convergence of the non-repetitive learning rule. Numerical simulations illustrate the effectiveness of the proposed control scheme and the validity of the conclusion.

  13. Structural Basis of IgE Binding to α- and γ-Gliadins: Contribution of Disulfide Bonds and Repetitive and Nonrepetitive Domains.

    Science.gov (United States)

    Mameri, Hamza; Brossard, Chantal; Gaudin, Jean-Charles; Gohon, Yann; Paty, Evelyne; Beaudouin, Etienne; Moneret-Vautrin, Denise-Anne; Drouet, Martine; Solé, Véronique; Wien, Frank; Lupi, Roberta; Larré, Colette; Snégaroff, Jacques; Denery-Papini, Sandra

    2015-07-29

    Wheat products cause IgE-mediated allergies. The present study aimed to decipher the molecular basis of α- and γ-gliadin allergenicity. Gliadins and their domains, the repetitive N-terminal and the nonrepetitive C-terminal domains, were cloned and expressed in Escherichia coli. Their secondary structures and their IgE binding capacity were compared with those of natural proteins before and after reduction/alkylation. Allergenicity was evaluated with sera from patients who had a wheat food allergy or baker's asthma. The secondary structures of natural and recombinant proteins were slightly different. Compared with natural gliadins, recombinant proteins retained IgE binding but with reduced reactivity. Reduction/alkylation decreased IgE binding for both natural and recombinant gliadins. Although more continuous epitopes were identified in the N-terminal domains of α- and γ-gliadins, both the N-terminal and C-terminal domains contributed to IgE binding. As for other members of the prolamin superfamily, disulfide bonds appear to be of high importance for IgE binding.

  14. Integrating Geo-Spatial Data for Regional Landslide Susceptibility Modeling in Consideration of Run-Out Signature

    Science.gov (United States)

    Lai, J.-S.; Tsai, F.; Chiang, S.-H.

    2016-06-01

    This study implements a data mining-based algorithm, the random forests classifier, with geo-spatial data to construct a regional and rainfall-induced landslide susceptibility model. The developed model also takes account of landslide regions (source, non-occurrence and run-out signatures) from the original landslide inventory in order to increase the reliability of the susceptibility modelling. A total of ten causative factors were collected and used in this study, including aspect, curvature, elevation, slope, faults, geology, NDVI (Normalized Difference Vegetation Index), rivers, roads and soil data. Consequently, this study transforms the landslide inventory and vector-based causative factors into the pixel-based format in order to overlay with other raster data for constructing the random forests based model. This study also uses original and edited topographic data in the analysis to understand their impacts to the susceptibility modeling. Experimental results demonstrate that after identifying the run-out signatures, the overall accuracy and Kappa coefficient have been reached to be become more than 85 % and 0.8, respectively. In addition, correcting unreasonable topographic feature of the digital terrain model also produces more reliable modelling results.

  15. Atypical epigenetic mark in an atypical location: cytosine methylation at asymmetric (CNN sites within the body of a non-repetitive tomato gene

    Directory of Open Access Journals (Sweden)

    Iusem Norberto D

    2011-05-01

    Full Text Available Abstract Background Eukaryotic DNA methylation is one of the most studied epigenetic processes, as it results in a direct and heritable covalent modification triggered by external stimuli. In contrast to mammals, plant DNA methylation, which is stimulated by external cues exemplified by various abiotic types of stress, is often found not only at CG sites but also at CNG (N denoting A, C or T and CNN (asymmetric sites. A genome-wide analysis of DNA methylation in Arabidopsis has shown that CNN methylation is preferentially concentrated in transposon genes and non-coding repetitive elements. We are particularly interested in investigating the epigenetics of plant species with larger and more complex genomes than Arabidopsis, particularly with regards to the associated alterations elicited by abiotic stress. Results We describe the existence of CNN-methylated epialleles that span Asr1, a non-transposon, protein-coding gene from tomato plants that lacks an orthologous counterpart in Arabidopsis. In addition, to test the hypothesis of a link between epigenetics modifications and the adaptation of crop plants to abiotic stress, we exhaustively explored the cytosine methylation status in leaf Asr1 DNA, a model gene in our system, resulting from water-deficit stress conditions imposed on tomato plants. We found that drought conditions brought about removal of methyl marks at approximately 75 of the 110 asymmetric (CNN sites analysed, concomitantly with a decrease of the repressive H3K27me3 epigenetic mark and a large induction of expression at the RNA level. When pinpointing those sites, we observed that demethylation occurred mostly in the intronic region. Conclusions These results demonstrate a novel genomic distribution of CNN methylation, namely in the transcribed region of a protein-coding, non-repetitive gene, and the changes in those epigenetic marks that are caused by water stress. These findings may represent a general mechanism for the

  16. Changes in rainfall thresholds for debris flow initiation and run-out on a local and regional scale in the Wenchuan earthquake area, SW China

    NARCIS (Netherlands)

    van Asch, Th.W.J.; Quan Luna, B.; Tang, C.; van Westen, A.; Alkema, D.; Fan, X.

    2013-01-01

    For the development of early warning systems for the initiation and run-out distances of debris flows, to avoid or mitigate intolerable risks, it is necessary to assess rainfall thresholds. However one must be aware that these thresholds can change. These changes can be ascribed to environmental and

  17. Crack path for run-out specimens in fatigue tests: is it belonging to high- or very-high-cycle fatigue regime?

    Directory of Open Access Journals (Sweden)

    A. Shanyavskiy

    2015-10-01

    Full Text Available Fatigue tests run-out specimens up to 106 – 5x107 load cycles are used to determine the stress level named “fatigue limit”. Nevertheless, it is not clear what kind of fatigue cracking takes or will take place in these specimens. To discuss this problem, fatigue tests of titanium alloy VT3-1 specimens have been performed under tension with different values of R-ratio and under rotating-bending after various thermo-mechanical treatments (tempering, surface hardening and their combinations. Well-known S-N curves in High-Cycle- Fatigue regime have been plotted with run-out specimens usually used for “fatigue limit” determination. Then, after fatigue tests, run-out specimens have been tensed up to their failure, and fracture surface analyses have been performed for all tested specimens. It is found that run-out specimens in all combinations of treatments, for different R-ratio, have fracture surfaces for crack path in Very-High-Cycle-Fatigue regime. Based on this result, all S-N curves have been reconstructed in duplex curves for High- and Very-High-Cycle-Fatigue regime without using knowledge about “fatigue limit”. Detailed fracture surfaces analyses have been developed, and crack paths have been compared for various combinations of materials and surface states.

  18. Coupled models of heat transfer and phase transformation for the run-out table in hot rolling

    Institute of Scientific and Technical Information of China (English)

    Shui-xuan CHEN; Jun ZOU; Xin FU

    2008-01-01

    Mathematical models are been proposed to simulate the thermal and metallurgical behaviors of the strip occurring on the run-out table (ROT) in a hot strip mill. A variational method is utilized for the discretization of the governing transient conduction-convection equation, with heat transfer coefficients adaptively determined by the actual mill data. To consider the thermal effect of phase transformation during cooling, a constitutive equation for describing austenite decomposition kinetics of steel in air and water cooling zones is coupled with the heat transfer model. As the basic required inputs in the numerical simulations, thermal material properties are experimentally measured for three carbon steels and the least squares method is used to statistically derive regression models for the properties, including specific heat and thermal conductivity. The numerical simulation and experimental results show that the setup accuracy of the temperature prediction system of ROT is effectively improved.

  19. Field Balancing and Harmonic Vibration Suppression in Rigid AMB-Rotor Systems with Rotor Imbalances and Sensor Runout

    Directory of Open Access Journals (Sweden)

    Xiangbo Xu

    2015-08-01

    Full Text Available Harmonic vibrations of high-speed rotors in momentum exchange devices are primary disturbances for attitude control of spacecraft. Active magnetic bearings (AMBs, offering the ability to control the AMB-rotor dynamic behaviors, are preferred in high-precision and micro-vibration applications, such as high-solution Earth observation satellites. However, undesirable harmonic displacements, currents, and vibrations also occur in the AMB-rotor system owing to the mixed rotor imbalances and sensor runout. To compensate the rotor imbalances and to suppress the harmonic vibrations, two control methods are presented. Firstly, a four degrees-of-freedom AMB-rotor model with the static imbalance, dynamic imbalance, and the sensor runout are described. Next, a synchronous current reduction approach with a variable-phase notch feedback is proposed, so that the rotor imbalances can be identified on-line through the analysis of the synchronous displacement relationships of the geometric, inertial, and rotational axes of the rotor. Then, the identified rotor imbalances, which can be represented at two prescribed balancing planes of the rotor, are compensated by discrete add-on weights whose masses are calculated in the vector form. Finally, a repetitive control algorithm is utilized to suppress the residual harmonic vibrations. The proposed field balancing and harmonic vibration suppression strategies are verified by simulations and experiments performed on a control moment gyro test rig with a rigid AMB-rotor system. Compared with existing methods, the proposed strategies do not require trial weights or an accurate model of the AMB-rotor system. Moreover, the harmonic displacements, currents, and vibrations can be well-attenuated simultaneously.

  20. Field Balancing and Harmonic Vibration Suppression in Rigid AMB-Rotor Systems with Rotor Imbalances and Sensor Runout.

    Science.gov (United States)

    Xu, Xiangbo; Chen, Shao

    2015-08-31

    Harmonic vibrations of high-speed rotors in momentum exchange devices are primary disturbances for attitude control of spacecraft. Active magnetic bearings (AMBs), offering the ability to control the AMB-rotor dynamic behaviors, are preferred in high-precision and micro-vibration applications, such as high-solution Earth observation satellites. However, undesirable harmonic displacements, currents, and vibrations also occur in the AMB-rotor system owing to the mixed rotor imbalances and sensor runout. To compensate the rotor imbalances and to suppress the harmonic vibrations, two control methods are presented. Firstly, a four degrees-of-freedom AMB-rotor model with the static imbalance, dynamic imbalance, and the sensor runout are described. Next, a synchronous current reduction approach with a variable-phase notch feedback is proposed, so that the rotor imbalances can be identified on-line through the analysis of the synchronous displacement relationships of the geometric, inertial, and rotational axes of the rotor. Then, the identified rotor imbalances, which can be represented at two prescribed balancing planes of the rotor, are compensated by discrete add-on weights whose masses are calculated in the vector form. Finally, a repetitive control algorithm is utilized to suppress the residual harmonic vibrations. The proposed field balancing and harmonic vibration suppression strategies are verified by simulations and experiments performed on a control moment gyro test rig with a rigid AMB-rotor system. Compared with existing methods, the proposed strategies do not require trial weights or an accurate model of the AMB-rotor system. Moreover, the harmonic displacements, currents, and vibrations can be well-attenuated simultaneously.

  1. Comment on "The reduction of friction in long-runout landslides as an emergent phenomenon" by Brandon C. Johnson et al.

    Science.gov (United States)

    Iverson, Richard M.

    2016-11-01

    Results from a highly idealized, 2-D computational model indicate that dynamic normal-stress rarefactions might cause friction reduction in long-runout landslides, but the physical relevance of the idealized dynamics has not been confirmed by experimental tests. More importantly, the model results provide no evidence that refutes alternative hypotheses about friction reduction mechanisms. One alternative hypothesis, which is strongly supported by field evidence, experimental data, and the predictions of a well-constrained computational model, involves development of high pore fluid pressures in deforming landslide material or overridden bed material. However, no scientific basis exists for concluding that a universal mechanism is responsible for friction reduction in all long-runout landslides.

  2. Changes in rainfall thresholds for debris flow initiation and run-out on a local and regional scale in the Wenchuan earthquake area, SW China

    OpenAIRE

    Asch, Th. W. J. van; B. Quan Luna; Tang, C.; Westen, A. Van; Alkema, D.; Fan, X.

    2013-01-01

    For the development of early warning systems for the initiation and run-out distances of debris flows, to avoid or mitigate intolerable risks, it is necessary to assess rainfall thresholds. However one must be aware that these thresholds can change. These changes can be ascribed to environmental and climate change as well as socio-economical changes. In the Wenchuan area in the Sichuan Province, SW China, changes in thresholds are related to a depletion of source materials for these debris fl...

  3. Runout prediction and dynamic characteristic analysis of a potential submarine landslide in Liwan 3-1 gas field

    Institute of Scientific and Technical Information of China (English)

    XIU Zongxiang; LIU Lejun; XIE Qiuhong; LI Jiagang; HU Guanghai; YANG Jianghui

    2015-01-01

    A large number of submarine landslides with different scales have been identified in the canyon area of the submarine pipeline route of Liwan 3-1 gas field. There is still much chance that submarine slope failures would happen, and the following mass movement would present great risk to the submarine pipeline. In view of this, a numerical prediction method based on Eulerian-Eulerian two-phase flow model is introduced to simulate the mass movement of potential submarine landslides. The sliding soil and ambient water are respectively simulated by Herschel-Bulkley rheology model and Newtonian fluid model. The turbulence is simulated using thek-e model. Compared with both the experiment data and Bing result, the two-phase flow model shows a good accuracy, and its result is more close to the actual situation; the dynamic coupling between soil and ambient water can be effectively simulated and the phenomena of hydroplaning and head detachment can be obtained. Finally, the soil movement of a potential submarine landslide is simulated as an example, according to the seismic profile in the canyon area. The result shows that the hydroplaning occurs during the movement process. The runout distance calculated by the two-phase flow model is 877 m, which is 27.1% larger than the Bing result. However, the peak front velocity of soil is relative small, with a maximum value of 8.32 m/s. The Bing program with a simple and rapid process can be used for a preliminary evaluation, while the two-phase flow model is more appropriate for an accurate assessment.

  4. Analysis of elastic stiffness for the leaf type holddown spring assembly with uniformly tapered thickness considering the point of taper runout

    Energy Technology Data Exchange (ETDEWEB)

    Song, Ki Nam [Korea Atomic Energy Research Institute, Daeduk (Korea, Republic of)

    1996-04-01

    In the case that the point of taper runout is outside the bent region of spring base, a formula to evaluate the elastic stiffness of the leaf type holddown spring (HDS) assembly with uniformly tapered thickness from t{sub 0} to t{sub 1} (t{sub 0}>t{sub 1}) has been analytically derived by applying the engineering beam theory and Casiliano`s theorem based on strain energy. It has found that taper runouts for the 14x14 and 17x17 type KOFA HDS were up to 2.2 mm and effects on their elastic stiffnesses were about 3.70%, and that the elastic stiffness of the HDS was mainly caused by bending moment. And in addition, for the HDS designed/manufactured from Westinghouse, elastic stiffnesses from the derived formula were in good agreement with those from the Westinghouse`s empirical formula. Therefore, the derived formula could be applicable to evaluating the elastic stiffness of any HDS with tapered thickness only with the informations of the geometric data and material properties of leaf springs regardness of the manufacturing companies. 11 tabs., 4 figs., 25 refs. (Author) .new.

  5. Changes in rainfall thresholds for debris flow initiation and run-out on a local and regional scale in the Wenchuan earthquake area, SW China.

    Science.gov (United States)

    van Asch, Theo; Luna, Byron Quan; Tang, Chenxiao; van Westen, Cees; Alkema, Dinand; Fan, Xuanmei

    2013-04-01

    For the development of early warning systems for the initiation and run-out distances of debris flows, to avoid or mitigate intolerable risks, it is necessary to assess rainfall thresholds. However one must be aware that these thresholds can change. These changes can be ascribed to environmental and climate change as well as socio-economical changes. In the Wenchuan area in the Sichuan Province, SW China, changes in thresholds are related to a depletion of source materials for these debris flows. The intensive Earthquake of 2008 in the Wenchuan area generated many co-seismic landslides, which delivered a lot of loose source material. It caused a dramatic increase in debris flow occurrences in the subsequent years. A preliminary model was designed, with entrainment processes driven by run-off water as the main triggering mechanism, to describe the relationship between rain input and debris flow run-out with the intention to assess rainfall thresholds for the start of debris flows and critical run out distances. The model was calibrated on the depositional volumes of debris flow events which occurred in individual catchments in August 2011. The calibrated model was used to construct rainfall intensity -duration threshold curves. These curves describe the thresholds for a critical run-out distance, determined by the outlet of the catchment, which was considered as the limit beyond which elements at risk situated in the main river plain are threatened. The research is focused on the change in these thresholds curves after a range of consecutive debris flow triggering rain events. It appeared that for individual catchments the rate of change of these thresholds can vary dramatically which is related to the location of available loose erodible material in the catchment. The model is also applied on a regional scale in the Jingxiu area. A method was proposed to made a general estimate of the time duration to arrive at a debris flow frequency level before the earthquake

  6. Experimental and theoretical investigation of the role of clay in subaqueous sediment flows and its effect on run-out distance

    Science.gov (United States)

    Hermidas, Navid; Luthi, Stefan; Eggenhuisen, Joris; Silva Jacinto, Ricardo; Toth, Ferenc; Pohl, Florian; de Leeuw, Jan

    2016-04-01

    Debris flows are driven by gravity, which in the tail region is overcome by the yield strength of the flow, forcing it to freeze. These flows are capable of achieving staggeringly large run-out distances on low gradients. The case in point, described in previous publications, is the flow which resulted in the deposit of Bed 5 of the Agadir megaslide on the north-west African margin. Debrites of this flow have been recorded several hundred kilometres away from the original landslide. Previous studies have attributed such long run-out distances to hydroplaning, low yield strength, and flow transformation. It is known that the net force acting on a volume of fluid in equilibrium is zero. In this work we show that clay-laden flows are capable of approaching equilibrium. The flows which can achieve the maximum run-out distance are cohesive enough to resist some of the surrounding disturbances, that can upset the equilibrium, and reach close to equilibrium conditions, yet are dilute enough to have low viscous stress, and relatively low yield strength and lose little sediment due to deposition. A flow that is not in equilibrium will always seek to approach equilibrium conditions by speeding up or slowing down, depositing sediment, eroding the substrate, contracting in the form of the tail approaching the head, stretching, entraining water and growing in height, or dewatering and collapsing. Here we present a theory that shows that two dimensional (2D) flows in equilibrium do not grow in height. 2D flume experiments were conducted on different mixtures of kaolinite, sand, silt, and water, on varying slopes and a transitionally rough bed (sand glued), and using various discharge rates, in order to map out different stages in the evolution of a density flow from a cohesive plug flow into a turbidity current. The following flow types were observed: high density turbidity currents, plug flows, and no flow. From the velocity profiles, certain runs demonstrated close to

  7. 液压阻拦机定长冲跑控制规律优化%Optimization and Kinetic Simulation of Constant Runout Control System of Arresting Gear

    Institute of Scientific and Technical Information of China (English)

    郑茂; 王超; 黄胜

    2013-01-01

    To gain the optimum control regularity of the constant runout control system,the kinetic simulation for MK7-3 arresting gear was completed and the control valve flow area of the constant runout was optimized using Hicks-Henne shape function and the steepest descent method.Finally,kinetic simulation of different weights,engaged speeds and thrusts indicates that different aircrafts can be arrested at a constant distance and that the loads on wires and the acceleration of aircrafts are proper,showing the validity and the safety of the optimized control regularity.%为确定舰载机最优阻拦定长冲跑控制规律,对美国MK7-3型液压阻拦机进行了动力学仿真,并采用Hicks-Henne形状函数和最速下降法对定长冲跑控制阀通流面积曲线进行了优化.对不同质量、进场速度和发动机推力的舰载机进行了阻拦仿真实验,结果表明:优化后的定长冲跑控制规律能使不同质量、进场速度和发动机推力的舰载机均在相同的阻拦距离上停下来,且钢索张力和舰载机加速度变化规律合理,证明了本文所述优化方法的合理性和安全性.

  8. 微细铣削过程中刀尖径向总跳动度的实验研究%Research on the Tool-point Radical Run-out of Micro Milling Process

    Institute of Scientific and Technical Information of China (English)

    李光俊; 高翼飞

    2015-01-01

    微细铣削过程中,刀尖径向总跳动度与每齿进给量在同一量级,其影响切削过程切削厚度,从而影响切削过程切削力。文章基于轴向铣微孔实验分析了微细铣削过程中主轴转速和刀具悬伸量对刀尖径向总跳动度的影响规律,采用线性回归最小二乘估计法建立刀尖径向总跳动度预测模型,并对预测模型进行显著性检验和拟合度检验,检验结果表明:预测模型可用于切削参数范围内刀尖径向总跳动量的预测。%In micro milling process, the tool-point radical run-out is comparable with the feed per tooth and will affect the chip thickness, ultimately impact the cutting forces. In this paper, micro drilling hole tests are carried out to analyze the influence principle of the spindle speed and the tool overhang on the tool-point rad-ical run-out;and based on the test results, the tool point radical run-out prediction model is built by using linear regression least square estimation method. In addition, the significance test and fitting degree test are conducted on the prediction model, which show that the prediction model is efficient for predicting the tool-point radical run-out in the range of test cutting parameters.

  9. 从动锥齿轮齿圈跳动专用检具设计与运用%Design And Application Of Special-purpose Tools For Driven Bevel Gear Tooth Flank Runout Checking

    Institute of Scientific and Technical Information of China (English)

    韦雪薇

    2012-01-01

      介绍一种车桥的从动锥齿轮齿圈跳动的检测方法,可运用于各汽车零部件厂家在来料检验环节监控从动锥齿轮质量稳定性。解决了该参数原来无法测量的状况,值得广泛的推广应用。%  This article introduces a checking method for driven bevel gear tooth flank runout checking of automobile axles, which can be used by automobile components and parts manufacturers to monitor quality stability of driven bevel gear during incoming material inspection period.The problem that the parameter cannot be measured has also be resolved,giving the method great value of extensive application.

  10. 基于GIS和Voellmy模型的泥石流运动堆积过程模拟%Debris Flow Run-out Process Simulation Based on the GIS Technology and Voellmy Model

    Institute of Scientific and Technical Information of China (English)

    陈伟

    2014-01-01

    Debris lfow is characterized with rapid speed and strong destructive force, furthermore, it has posed a great threat to the development and construction of mountain towns and people life as well as property safety. At present, to analyze the debris run-out has been a hotpot and dififculty in the research of debris lfow. Based on the GIS technology and the proximate Voellmy solver, and taking a typical debris lfow gulley as example, this paper takes advantage of the numerical stimulation method to carry on the analysis for the whole process of debris lfow movement and deposit, including max velocity, pressure, momentum, flow fleight and deposit area, in order to support the hazard assess and prevention of debris lfow.%泥石流流体具有速度快、破坏力强的特征,严重威胁着山区城镇的发展建设、群众生命财产安全。如何针对泥石流运动堆积过程进行模拟一直是泥石流研究的热点和难点。本文基于GIS技术以及近似Voellmy解的连续介质理论,建立了泥石流动力模型,采用数值模拟仿真的方法,以一典型泥石流沟为研究实例进行分析,通过模拟泥石流运动、堆积的动力过程,分析其最大速度、压力、过流量、堆积高度以及堆积面积,为后期泥石流危险性评价区划及防治提供有力支撑。

  11. 汶川8.0级地震震区溃决型和一般型泥石流冲出量研究%Study on Run-out Amount of Break and General Debris Flows in Wenchuan Earthquake Area

    Institute of Scientific and Technical Information of China (English)

    方群生; 唐川

    2016-01-01

    汶川8.0级地震后,震区在强降雨作用下不仅诱发形成大量的一般暴雨型泥石流灾害,还诱发形成危害性更大的溃决型泥石流。通过泥石流勘查应急报告和野外实地调查,核实选取了汶川震区9条溃决型泥石流沟和34条一般型泥石流沟冲出量的相关参数作为样本数据,先对汶川震区溃决型泥石流的特征进行分析总结,其次对比分析汶川震区溃决型泥石流与一般型泥石流冲出量的特点及其是否堵江的原因,结果表明溃决型泥石流冲出量较一般型泥石流要大出几十倍,且比一般型泥石流更易造成堵江。最后建立一般型泥石流冲出量多因子统计预测模型,提高了一般型泥石流冲出量普遍预测模型的精度,验证显示该预测模型对汶川震区一般型泥石流冲出量的预测具有科学有效性。研究结果为进一步深入研究震区溃决型泥石流提供理论依据,也为震后灾区一般型泥石流的减灾防灾工程设计提供计算方法。%A large number of general debris flows were triggered by rainstorm in the seismic area after Wen-chuan earthquake.Meanwhile,bam-break debris flows were triggered by rainstorm.Therefore,we select the inves-tigation data from the report of emergency exploration for debris flow in the seismic area and field investigation which conduct 34 common debris flow gullies and 9 break debris flow gullies.Firstly,we analyze and summarize the characteristics of break debris flow in Wenchuan earthquake area.Secondly,break debris flow is easier to block the river than general debris flow,because the run-out amount of break debris flow is several times larger than the common debris flow.Finally,applying the multivariate regression analysis,a multiple-factor and regression-statisti-cal model which has been improved the accuracy ofthe runout volume is established to estimate the run-out volume of the common debris flow.The validation shows that

  12. 2D Nano-Motion Actuator for Precise Track Following

    Science.gov (United States)

    Mori, Shigeki; Sato, Yuudai; Sakurada, Akira; Naganawa, Akihiro; Shibuya, Yotsugi; Obinata, Goro

    The authors proposed a new actuator for track following on a spin-stand that evaluated magnetic heads and media for high density magnetic recording with high speed. The new actuator was named “Nano-Motion Actuator (NMA)” by the authors. At the present time, effect of azimuth angle which causes between a center line of a head slider and a tangential direction of the track is increasingly actualized as a track pitch of the head becomes narrow. Therefore, if a discrete track media (DTM) will be put to practical use, the effect of the azimuth angle will be actualized more clearly. Because, DTM will have large RRO (Repeatable Run-Out) that is caused by eccentricity error between a medium and a hub of an air-spindle. Furthermore, NRRO (Non-Repeatable Run-Out) which is caused by mechanical vibration of the air-spindle, flutter of the medium, turbulence around a HGA (Head gimbals Assembly) and so on is overlapped with the RRO. Especially in case of the large NRRO, since the azimuth angle will rapidly change, compensations of the azimuth angle should be absolutely necessary. Therefore, precision positioning actuator with high speed on an X-Y plane which is coplanar will be required the evaluation of the high density magnetic recording. We proposed a new actuator which was consisted of a NMA mechanism and a translation mechanism. The translation mechanism was composed of a stacked piezoelectric that was supported by two elastic springs. The new actuator that was called “2D Nano-Motion Actuator (2D NMA)” could move within 10 square micrometer and be positioned by nanometer resolution with high speed.

  13. SIMULATION AND ANALISIS OF SLIDING EVOLUTION PROCESS AND LONG RUN-OUT SLIDING MECHANISM FOR PLANE SLIDING OF CUTTING SLOPE%路堑边坡平面滑动演化过程及远程滑动机制的模拟与分析

    Institute of Scientific and Technical Information of China (English)

    王浩; 孙木子; 马新凯; 廖小平; 林一夫; 吴志刚

    2015-01-01

    永宁高速公路 K117滑坡路段原为在泥质粉砂岩单斜地层内开挖2级形成的路堑边坡,开挖后产生典型平面滑动,在中部滑床形成长约25m 的滑动槽,产生最远达35m 的远程滑距,其成因机制复杂。本文在对滑坡基本特征及孕育过程开展详细调查研究的基础上,采用节理有限单元法对该滑坡经路堑开挖导致高位坍滑、刷方变更后触发高速远程滑塌、滑塌后壁残留滑体牵引松动,以及对其实施卸载、支挡回填及锚固的治理过程开展数值模拟,再现了该滑坡孕育发展全过程及其稳定性演化规律;分析了该边坡破坏的平面滑动机构及滑动面的物理力学特征,论述了该类滑坡启动高速远程滑动的开挖松弛致滑机理和裂隙充水致滑机理,最后提出了预测及治理该类滑坡的6点建议。研究表明,在单斜地层开挖路堑,使顺倾向软弱结构面临空暴露时,可能诱发边坡整体卸荷松弛,产生较大的不平衡滑坡推力,而卸荷松动产生的张裂隙导致滑坡对降雨入渗十分敏感,不平衡力和裂隙水压力的共同作用可迅速剪断滑面,伴随势能向动能的转化,产生高速远程滑动。%K117 landslide of Yong-Ning highway is a cutting slope with two excavation stages in argillaceous siltstone of monoclinic layer.The formation mechanism of this landslide is complex because it is the long run-out plane sliding as far as 35m and the sliding pit as long as 25m on slide bed when excavated.Based on the detailed investigation to its basic characteristics and development process,the landslide is simulated by joint finite element method in the process of its slide of three stages and landslide treatment.Firstly,the paper reappears the whole gestating process and stability evolving regulations of the landslide.It analyzes the plane sliding mechanism and the physical and mechanical characteristics of sliding surface

  14. Huge long-runout landslide characteristics and for- mation mechanism:A case study of the Luanshibao landslide, Litang County, Tibetan Plateau%青藏高原东缘理塘乱石包高速远程滑坡发育特征与形成机理

    Institute of Scientific and Technical Information of China (English)

    郭长宝; 杜宇本; 佟元清; 张永双; 张广泽; 张敏; 任三绍

    2016-01-01

    prospecting, trenching, and geological dating data, the authors studied the development characteristics of the Luanshibao landslide and investigated its formation mechanism. The Luanshibao long-runout landslide has the following features: ① The Luanshibao landslide is located on the northeastern margin of the Maoyaba Basin in Litang County, western Sichuan. The sliding direction of the landslide is perpendicular to the northwestern segment of the Litang-Dewu fault, with the top part of the Luanshibao landslide approaching the current snow line. ②The maxi⁃mum sliding distance of the Luanshibao landslide is 3.83km; the elevation difference between the back wall of the landslide and the accumulation zone at the leading edge is approximately 820m, with a sliding body volume of approximately 0.64×108~0.94×108m3 and an average sliding velocity of approximately 53.25m/s. ③ The dating data indicate that the Luanshibao landslide occurred at about 1980±30a BP.④The compositional lithology of the landslide rocks is mainly granite, and the joint fractures are developed as cracked rocks under the impact of long-term tectonic dynamics and freezing weathering. The analysis indicates that the Luanshibao landslide has been substantially affected by the fault structure, terrain topography, and ancient climate change, and its formation mechanism is complicated:①Since the Holocene, the Litang-Dewu fault has experienced frequent, strong earthquake activity. The strong earthquakes resulting from the fault activity might have been one of the main factors for the formation of the Luanshibao landslide. Under the impact of earthquakes, the seismic wave at the top of the slope would be"amplified", producing a vertical accel⁃eration greater than the horizontal acceleration. The rock bodies experienced shock expansion and were thrown, forming the long-runout landslide. ② Dating back to approximately 2000a BP, the temperature change in the Tibetan Plateau area was relatively large, and

  15. Multimodal behavioral treatment of nonrepetitive, treatment-resistant nightmares: a case report.

    Science.gov (United States)

    Tanner, Barry A

    2004-12-01

    A 23-yr.-old young woman presenting with a 17-yr. history of nightmares was treated with a variety of behavioral and self-regulatory techniques. The nightmares were unusual in that they did not have an obviously common theme as in most published reports, and, therefore, did not readily lend themselves to several frequently used techniques. Although previous treatment episodes had not affected the incidence of the nightmares, a combination of relaxation procedures, a mnemonic to increase lucid dreaming, and dream rehearsal upon waking from a nightmare resulted in a sharp decrease in the frequency of nightmares in four sessions. Further improvement was reported over the next nine months as additional techniques were introduced and other problems treated, and was maintained during a 9-mo. follow-up.

  16. Feline Non-repetitive Mitochondrial DNA Control Region Database for Forensic Evidence

    Science.gov (United States)

    Grahn, R. A.; Kurushima, J. D.; Billings, N. C.; Grahn, J.C.; Halverson, J. L.; Hammer, E.; Ho, C.K.; Kun, T. J.; Levy, J.K.; Lipinski, M. J.; Mwenda, J.M.; Ozpinar, H.; Schuster, R.K; Shoorijeh, S.J.; Tarditi, C. R.; Waly, N.E.; Wictum, E. J.; Lyons, L. A.

    2010-01-01

    The domestic cat is the one of the most popular pets throughout the world. A by-product of owning, interacting with, or being in a household with a cat is the transfer of shed fur to clothing or personal objects. As trace evidence, transferred cat fur is a relatively untapped resource for forensic scientists. Both phenotypic and genotypic characteristics can be obtained from cat fur, but databases for neither aspect exist. Because cats incessantly groom, cat fur may have nucleated cells, not only in the hair bulb, but also as epithelial cells on the hair shaft deposited during the grooming process, thereby generally providing material for DNA profiling. To effectively exploit cat hair as a resource, representative databases must be established. This study evaluates 402 bp of the mtDNA control region (CR) from 1,394 cats, including cats from 25 distinct worldwide populations and 26 breeds. Eighty-three percent of the cats are represented by 12 major mitotypes. An additional 8.0% are clearly derived from the major mitotypes. Unique sequences were found in 7.5% of the cats. The overall genetic diversity for this data set was 0.8813 ± 0.0046 with a random match probability of 11.8%. This region of the cat mtDNA has discriminatory power suitable for forensic application worldwide. PMID:20457082

  17. The Cosine Error: A Bayesian Procedure for Treating a Non-repetitive Systematic Effect

    Directory of Open Access Journals (Sweden)

    Lira Ignacio

    2016-08-01

    Full Text Available An inconsistency with respect to variable transformations in our previous treatment of the cosine error example with repositioning (Metrologia, vol. 47, pp. R1–R14 is pointed out. The problem refers to the measurement of the vertical height of a column of liquid in a manometer. A systematic effect arises because of the possible deviation of the measurement axis from the vertical, which may be different each time the measurement is taken. A revised procedure for treating this problem is proposed; it consists in straightforward application of Bayesian statistics using a conditional reference prior with partial information. In most practical applications, the numerical differences between the two procedures will be negligible, so the interest of the revised one is mainly of conceptual nature. Nevertheless, similar measurement models may appear in other contexts, for example, in intercomparisons, so the present investigation may serve as a warning to analysts against applying the same methodology we used in our original approach to the present problem.

  18. Feline non-repetitive mitochondrial DNA control region database for forensic evidence.

    Science.gov (United States)

    Grahn, R A; Kurushima, J D; Billings, N C; Grahn, J C; Halverson, J L; Hammer, E; Ho, C K; Kun, T J; Levy, J K; Lipinski, M J; Mwenda, J M; Ozpinar, H; Schuster, R K; Shoorijeh, S J; Tarditi, C R; Waly, N E; Wictum, E J; Lyons, L A

    2011-01-01

    The domestic cat is the one of the most popular pets throughout the world. A by-product of owning, interacting with, or being in a household with a cat is the transfer of shed fur to clothing or personal objects. As trace evidence, transferred cat fur is a relatively untapped resource for forensic scientists. Both phenotypic and genotypic characteristics can be obtained from cat fur, but databases for neither aspect exist. Because cats incessantly groom, cat fur may have nucleated cells, not only in the hair bulb, but also as epithelial cells on the hair shaft deposited during the grooming process, thereby generally providing material for DNA profiling. To effectively exploit cat hair as a resource, representative databases must be established. The current study evaluates 402 bp of the mtDNA control region (CR) from 1394 cats, including cats from 25 distinct worldwide populations and 26 breeds. Eighty-three percent of the cats are represented by 12 major mitotypes. An additional 8.0% are clearly derived from the major mitotypes. Unique sequences are found in 7.5% of the cats. The overall genetic diversity for this data set is 0.8813±0.0046 with a random match probability of 11.8%. This region of the cat mtDNA has discriminatory power suitable for forensic application worldwide.

  19. A New Revised DNA Cramp Tool Based Approach of Chopping DNA Repetitive and Non-Repetitive Genome Sequences

    Directory of Open Access Journals (Sweden)

    V.Hari Prasad

    2012-11-01

    Full Text Available In vogue tremendous amount of data generated day by day by the living organism of genetic sequences and its accumulation in database, their size is growing in an exponential manner. Due to excessive storage of DNA sequences in public databases like NCBI, EMBL and DDBJ archival maintenance is tedious task. Transmission of information from one place to another place in network management systems is also a critical task. So To improve the efficiency and to reduce the overhead of the database need of compression arises in database optimization. In this connection different techniques were bloomed, but achieved results are not bountiful. Many classical algorithms are fails to compress genetic sequences due to the specificity of text encoded in dna and few of the existing techniques achieved positive results. DNA is repetitive and non repetitive in nature. Our proposed technique DNACRAMP is applicable on repetitive and non repetitive sequences of dna and it yields better compression ratio in terms of bits per bases. This is compared with existing techniques and observed that our one is the optimum technique and compression results are on par with existing techniques.

  20. The importance of erosion for debris flow runout modelling from applications to the Swiss Alps

    OpenAIRE

    F. Frank; B. W. McArdell; Huggel, C; A. Vieli

    2015-01-01

    This study describes an investigation of channel-bed erosion of sediment by debris flows. An erosion model, developed using field data from debris flows at the Illgraben catchment, Switzerland, was incorporated into the existing RAMMS debris-flow model, which solves the 2-D shallow-water equations for granular flows. In the erosion model, the relationship between maximum shear stress and measured erosion is used to determine the maximum potential erosion depth. Additionally,...

  1. GIS-based cell model for simulating debris flow runout on a fan

    Science.gov (United States)

    Gregoretti, Carlo; Degetto, Massimo; Boreggio, Mauro

    2016-03-01

    A GIS-based cell model, based on a kinematic approach is proposed to simulate debris flow routing on a fan. The sediment-water mixture is modeled as a monophasic continuum, and the flow pattern is discretized by square cells, 1 m in size, that coincide with the DEM cells. Flow occurs from cells with a higher mixture free surface to those with a lower mixture free surface. A uniform-flow law is used if the elevation of the former cell is higher than that of the latter; otherwise, the flow is simulated using the broad-crested weir law. Erosion and deposition are simulated using an empirical law that is adjusted for a monophasic continuum. The sediment concentration in the routing volume is computed at each time step and controls both erosion and deposition. The cell model is used to simulate a debris flow that occurred on the Rio Lazer (Dolomites, North-Eastern Italian Alps) on November 4th, 1966. Furthermore, the hydrologic and the hydraulic conditions for the initiation of debris flow are simulated, providing the solid-liquid hydrograph of the resulting debris flow. A number of simulations has been carried out with physically reasonable parameters. The results are compared with the extension of the debris-flow deposition area and the map of observed depths of deposited sediments. This comparison shows that the proposed model provides good performance. The analysis of sensitivity carried out by systematically varying the model parameters shows that lower performances are associated with parameter values that are not physically reasonable. The same event is also simulated using a cellular automata model and a finite volume two-dimensional model. The results show that the two models provide a sediment deposition pattern less accurate than that provided by the present cell model.

  2. Modeling debris-flow runout patterns on two alpine fans with different dynamic simulation models

    Directory of Open Access Journals (Sweden)

    K. Schraml

    2015-02-01

    Full Text Available Predicting potential deposition areas of future debris-flow events is important for engineering hazard assessment in alpine regions. For this, numerical simulation models are commonly used tools. However, knowledge of appropriate model parameters is essential but often not available. In this study we use two numerical simulation models, RAMMS-DF (Rapid Mass Movement System – Debris Flow and DAN3D (Dynamic Analysis of Landslides in Three Dimensions, to back-calculate two well-documented debris-flow events in Austria and to compare the range and sensitivity of input parameters for the Voellmy flow model. All simulations are based on the same digital elevation model with a 1 m resolution and similar initial conditions. Our results show that both simulation tools are capable of matching observed deposition patterns. The best fit parameter set of μ [–] and ξ [m s−2] range between 0.07–0.11 and 200–300 m s−2, respectively, for RAMMS-DF, and 0.07–0.08 and 300–400 m s−2, respectively, for DAN3D. Sensitivity analyses show a higher sensitivity of model parameters for the DAN3D model than for the RAMMS-DF model. This study shall contribute to the evaluation of realistic model parameters for simulation of debris-flows in steep mountain catchments and highlights the sensitivity of the models.

  3. Factors Influencing Occurrence, Scale, Mobility, Runout, and Morphology of Mass Movements on the Continental Slope

    Science.gov (United States)

    2016-06-07

    distribution unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT 15. SUBJECT TERMS 16. SECURITY CLASSIFICATION OF: 17 . LIMITATION OF ABSTRACT Same as Report...SHELVES AND SLOPES”, SEPM- IAS Research Conference, Sicily, September 14-19th 1998, Abstract. Lee, H.J., , Dartnell, P., Minasian, D., Wong, F., Israel...Eel River Margin (California) and Saguenay Fjord (Québec) sediments. . In: STRATCON 󈨦: “STRATA AND SEQUENCES ON SHELVES AND SLOPES”, SEPM- IAS

  4. Seismic Signals reveal Precursors, Force History and Runout Dynamics of the Tsunami-creating Askja Caldera Landslide, July 21, 2014

    Science.gov (United States)

    Schöpa, A.; Chao, W. A.; Burtin, A.; Hovius, N.

    2016-12-01

    We have analysed signals from a network of 52 seismic stations that recorded a large landslide at the steep-sided Askja caldera, Central Iceland, on 21 July 2014. As no direct observations where made, the seismic signals are a very valuable record not only to describe the landslide dynamics in great detail but also to identify triggers and precursors of the slide useful for early warning purposes. This study is motivated by the high hazard potential of the side as the landslide created a tsunami in the caldera lake with waves up to 60 m high reaching famous tourist spots at the northern lake shore. Analysis of the high frequencies reveals that the main slope failure started at 23.24UTC. The relatively long rise time of 40 s until the maximum peak ground velocity was reached points towards cascading failure of the caldera wall. The high seismic energies recorded during the first two minutes of the slide are the result of colliding and impacting blocks. Velocity peaks in the seismic signals following the main failure are indicative for subsequent slope failures that occur less frequent, with shorter duration and lower amplitude during the twelve hours after the main event. The high frequency records of the stations up to 30 km away from the landslide source area show that the background noise level started to increase 20 min before the main failure, with amplitudes up to three times the background level about seven minutes before the main slide. Five minutes before the main failure, amplitudes decreased back to the background level. The characteristic increase and decrease in ground velocities before the main landslide could be implemented in a monitoring and early warning system of the caldera walls at Askjas. Inversion of the long-period signals (0.025-0.05 Hz) enables us to describe the history of the forces acting on the Earth during the landslide. The maximum acceleration of the moving mass was reached 40 s after the start of the slide with unloading forces directed to the SE, in the opposite direction of the landslide path. After the transition from acceleration to deceleration, the force vectors strike to the NW, the reloading direction of the Earth. Calculated horizontal and vertical total displacements of 1258 m and 411 m as well as the inverted location of the landslide at the SE side of the caldera lake are consistent with field observations.

  5. Computing Debris-flow Mobilization and Run-out with a Two-phase Depth-averaged Model

    Science.gov (United States)

    George, D. L.; Iverson, R. M.

    2011-12-01

    Large-scale, shallow earth-surface flows, such as river flows, overland flooding, and tsunami propagation and inundation, are commonly modeled with depth-averaged equations for the evolution of mass and momentum distributions. Depth-averaging three-dimensional conservation equations results in a tractable two-dimensional model that predicts macroscopic flow features with reasonable accuracy. For example, the simplest of the depth-averaged models---the shallow water equations---has proven to accurately describe water flooding and inundation. We have developed a depth-averaged, two-phase model applicable to granular-fluid mixtures such as landslides and debris flows. While the model relies on relatively simple assumptions for Coulomb frictional stress, the governing equations are more complex than those for shallow water flow. Our new equations include important feedback effects due to coupled evolution of the solid volume fraction and pore-fluid pressure, which mediates frictional stress. While pore-fluid pressure has long been known to be an important factor influencing debris-flow mobility, previous models lacked explicit coupling between pressure and granular dilation. Consequently, traditional models have also lacked the ability to account for the quasi-static transition of a stable mass of water-laden sediment into a debris flow. These models must be initialized by assuming a force balance far from equilibrium, ignoring the important transition to instability. By explicitly tracking the coupled pore-fluid pressure and solid volume fraction, our model captures this important transition and therefore can be used to investigate stability and mobility in addition to flow routing and deposition. Our model equations are a nonlinear hyperbolic system similar in mathematical structure to the shallow water equations, but having two additional equations for the solid volume fraction and pore-fluid pressure. Because of the mathematical similarities, numerical techniques that have been developed specifically for the shallow water equations [George, J. Comput. Phys, 227(6), 3089-3113, 2008] can be modified and extended to the debris-flow equations. We recently developed a numerical code for solving our one-dimensional model and have compared computational results to data collected at the USGS debris-flow flume. Initial comparisons are encouraging for reproducing flow dynamics as well as mobilization with reasonable accuracy.

  6. Runout distance and dynamic pressure of pyroclastic density currents: Evidence from 18 May 1980 blast surge of Mount St. Helens

    Science.gov (United States)

    Gardner, J. E.; Andrews, B. J.

    2016-12-01

    Pyroclastic density currents (flows and surges) are one of the most deadly hazards associated with volcanic eruptions. Understanding what controls how far such currents will travel, and how their dynamic pressure evolves, could help mitigate their hazards. The distance a ground hugging, pyroclastic density current travels is partly limited by when it reverses buoyancy and lifts off into the atmosphere. The 1980 blast surge of Mount St. Helens offers an example of a current seen to lift off. Before lofting, it had traveled up to 20 km and leveled more than 600 km3 of thick forest (the blowdown zone). The outer edge of the devastated area - where burned trees that were left standing (the singe zone) - is where the surge is thought to have lifted off. We recently examined deposits in the outer parts of the blowdown and in the singe zone at 32 sites. The important finding is that the laterally moving surge travelled into the singe zone, and hence the change in tree damage does not mark the run out distance of the ground hugging surge. Eyewitness accounts and impacts on trees and vehicles reveal that the surge consisted of a fast, dilute "overcurrent" and a slower "undercurrent", where most of the mass (and heat) was retained. Reasonable estimates for flow density and velocity show that dynamic pressure of the surge (i.e., its ability to topple trees) peaked near the base of the overcurrent. We propose that when the overcurrent began to lift off, the height of peak dynamic pressure rose above the trees and stopped toppling them. The slower undercurrent continued forward, burning trees but it lacked the dynamic pressure needed to topple them. Grain-size variations argue that it slowed from 30 m/s when it entered the singe zone to 3 m/s at the far end. Buoyancy reversal and liftoff are thus not preserved in the deposits where the surge lofted upwards.

  7. How does organic matter affect the head velocity and run-out distance of cohesive sediment gravity flows?

    Science.gov (United States)

    Craig, Melissa; Baas, Jaco; Amos, Kathryn; Strachan, Lorna; Baker, Megan

    2016-04-01

    Despite over 50 years of multidisciplinary research on the flow mechanics and deposits of submarine saline density currents and sediment gravity flows, the flow dynamics and depositional processes of clay-rich gravity flows remain poorly understood. Cohesive clay can alter the flow rheology as a result of the electrochemical forces of attraction between individual particles. These forces may induce particle aggregation, leading to the formation of floccules and more pervasive cohesive structures, called gels. Through flocculation and gelling, clay particles can enhance or dampen turbulent forces in sediment gravity flows, such that increasing the cohesive sediment content causes a transition from turbulent, Newtonian flow, via transient-turbulent flow, to laminar, non-Newtonian debris flow. Because the flow rheology controls the depositional style, a thorough understanding of how flow composition relates to flow rheology is essential for our interpretation of the architecture and the palaeo-environmental setting of submarine deposits in outcrop and core. In the natural environment, clay-rich sediments are commonly associated with the presence of organic matter. The effect of organic matter, in particular 'sticky' extracellular polymeric substances (EPS), on the flocculation and gelling within clay-laden flows is reasonably well known for tidal flows in shallow-marine environments, but the impact of cohesive organic matter on the dynamics of sediment gravity flows has not been explored yet. A complex interaction between physical and biological forces has been found to influence the stability of sedimentary deposits. Here, the influence of similar interactions for clay and EPS suspended within sediment gravity flows is presented. The above research gaps were addressed by means of flume experiments that recorded changes in dynamic behaviour of sediment gravity flows with variable amounts of biologically cohesive xanthan gum (a commonly used proxy for natural EPS) and physically cohesive kaolin clay (one of the most common clay minerals on Earth). Provisional results indicate that very small quantities of EPS - several orders of magnitude smaller than the quantity of clay - are sufficient to enhance flocculation and reduce flow velocity compared to a flow that lacks EPS. This finding has the potential to change our understanding of sediment gravity flows in the natural environment, where biological matter is ubiquitous.

  8. A study on histopathology of craniomandibular joint cause d by non-repetitive anterior disc displacement%不可复性盘前移位致颞下颌关节的病理组织学研究

    Institute of Scientific and Technical Information of China (English)

    焦国良; 王永海; 王政民; 江泓; 耿文彦; 郭宏

    2001-01-01

    Objective To study the effect of disc displacement on tem poromandibular joint. Methods The right disc displacement was created by incising t he l ateral, medial and anterior attachment and anteriorly fixing the disc to the zy gomatic arch in 6 New Zealand rabbits. The left joint served as a co ntrol. The animals were killed at 4 weeks and the craniomandibular joint tissues were excised under dissecting microscope.  Results Histologic examination showed that all 6 joints under disc displacement had evidence of histopatho logical changes including irregular fibrous thickening of the articular soft tis sue cover, chondrocyte proliferation, neonatal chondrocyte with large nucleus, double neclei in the disc and disordered collager fiber in the posterior attachment. N o histologic changes were observed in the control joint. Conclusions The results suggest that surgically induced disc displacement causes histologic changes and form changes of temporomandibular joi nt in rabbits, which is characterized by progressive remodeling in the con dylion and degenerative changes in the disc and posterior attachment in the ea rly period.%目的 研究盘前移位对兔颞下颌关节组织的影响。 方法 对6只成年新西兰大耳白兔的右侧颞下颌关节分别切除盘前及内 外侧韧带,然后将关节盘前拉,用丝线固定于颧弓部,造成不可复性盘前移位。左侧颞下颌 关节为非手术对照。术后4周处死动物,解剖显微镜下切取关节组织,常规处理,石蜡包埋 ,HE染色。 结果 手术侧关节髁突表面纤维组织呈局灶性增厚,软骨细胞增生活跃 ,关节盘出现大量新生的软骨细胞,核大,深染或双核,双板区纤维组织排列紊乱。对照关 节则无组织学异常表现。 结论 不可复性盘前移位可造成兔颞下颌关节形态及组织学变化,其早 期组织学特点为髁状突的进行性改建与关节盘及双板区的退行性改建并存。

  9. Long-runout landslide occurred in snowmelt period at the Higashi-kubiki Hill, Niigata, Japan: effects of snowpack on behavior of landslide movements

    Science.gov (United States)

    Kimura, Takashi; Hatada, Kazuhiro; Maruyama, Kiyoteru; Noro, Tomoyuki

    2013-04-01

    The mountain areas and the western part of Japan, along the Japan Sea, have over 1.0 m snow accumulation in every winter. For this reason, snowmelt-induced landslides occur frequently in these regions. If a landslide occurs particularly in early snowmelt period, abundant snow potentially causes the landslide to travel long distance. However, because there have been few literatures reported details of landslide movements in deep snow condition, our understanding of landslide movements affected by snow is still limited. This work reports movements and topographies of the Kokugawa landslide, occurred in early snowmelt period at the Higashi-kubiki Hill, Niigata, and discusses the effects of snowpack on behavior of landslide movements. On 7th March 2012, a snowmelt-induced landslide occurred at gentle slope (10-20° ) of the Higashi-kubiki Hill, adjacent to the Takada floodplain, Niigata, Japan, and destroyed eleven houses. Geology of the site consists of Neogene marine mudstone and Early Pleistocene conglomerate, while the slope surface is covered by loose materials (7-8m thick) composed of old colluvial deposits and spoil of gravel extraction in the 1980s. The Kokugawa landslide occurred initially as a rotational slide, which continued to enlarge until the afternoon of 8th, then it tuned into earthflow. The estimated earthflow volume was 750,000 m3. Although the outer part of the sliding mass spread out and deposited at the foot of hill, 350-500 m downward from the top of the scarp, the main body of the sliding mass continued to move rapidly (approximately 15 m/h) without spread out after reaching flat paddy field. When the landslide occurred, about two meters snow covered the site. Snow on the paddy field was pushed by the sliding mass and swelled up several meters above the snow surface level. The swelled snow formed moraine-like snowpack of 5-20 m width. The sliding mass including the snowpack reached houses 250 m apart from the foot of hill on morning of 10th, and stopped after destroying them. The angle of apparent friction of the landslide after the stoppage was 0.15, which is as low as debris flows or extremely large landslides. From field observation tied up with interpretations of airborne LiDAR and photography, we found that lateral ridges developed along the right side of the mass on the paddy field. At the boundary between the ridge and snowpack, slickenline was observed on flank of the ridge. Ground surface beneath the ridge was appeared to be undisturbed. Meanwhile, boring cores and trench profiles at the center of the mass revealed that about 1.0 m thick clay layer of the paddy field was lost, suggesting erosion of the ground by the sliding mass. These results indicate that the long travel distance of the Kokugawa landslide can be attributed to lateral confinement by compacted moraine-like snowpack.

  10. Jiweishan rapid and long run-out landslide-debris flow dynamic characteristics analysis%鸡尾山高速远程滑坡—碎屑流动力学特征分析

    Institute of Scientific and Technical Information of China (English)

    高杨; 殷跃平; 邢爱国; 李滨; 冯振

    2013-01-01

    以武隆鸡尾山滑坡为例,通过灾害形成地质环境条件的调查,概述了鸡尾山滑坡失稳诱发因素,包括:上硬下软的地层结构、岩溶发育、高陡地形地貌条件和采矿活动等;介绍了鸡尾山斜倾厚层滑坡视向滑动的基本模式,为“后部块体驱动-前缘关键块体瞬时失稳”.在此基础上,根据鸡尾山滑坡的运动和堆积特征,将滑坡分为滑源区和堆积区,通过二维DAN-W模拟,选取Frctional、Voellmy等流变模型,模拟了滑坡运动的整个过程,得到滑坡堆积体的体积、厚度和滑坡运动速度的变化规律,与实际情况基本一致.并且为西南山区高速远程滑坡成灾范围及滑动堆积特征的模拟分析提供了相应的依据.

  11. DISCUSSION ON LONG RUN-OUT SLIDING MECHANISM OF DONGHEKOU LANDSLIDE-DEBRIS FLOW%东河口滑坡-碎屑流高速远程运移机制探讨

    Institute of Scientific and Technical Information of China (English)

    孙萍; 张永双; 殷跃平; 汪发武; 吴树仁; 石菊松

    2009-01-01

    青川东河口滑坡-碎屑流是"5·12"汶川大地震触发的典型高速远程滑坡,滑坡自高程1300m处开始滑动,总滑程约2400m,致使780余人遇难.野外调研结果表明,该滑坡自启动到最终静止,分别经历了滑坡启动阶段、重力加速阶段、圈闭气垫效应飞行阶段、撞击折返阶段及长距离滑动堆积阶段5个重要动力过程,最终抵达下寺河左岸的红花地村并形成堰塞湖.文中通过对该高速远程滑坡-碎屑流的地质背景及形态特征进行剖析认为,东河口滑坡启动区的断层破碎带、局部凸起地形以及力学性质较差的千枚岩、板岩的存在,对该滑坡的启动均有着显著影响;滑坡体在运行一段距离后是否可以继续保持高速远程滑动,除了有利的地形外,滑体滑动路径上高含水量的溪流堆积物的存在,是促使该滑坡成为高速远程滑坡-碎屑流的重要原因之一.

  12. INVESTIGATION OF A HIGH SPEED AND LONG RUN-OUT ROCKSLIDE-DEBRIS FLOW AT DAZHAI IN GUANLING OF GUIZHOU PROVINCE%贵州关岭大寨高速远程滑坡-碎屑流研究

    Institute of Scientific and Technical Information of China (English)

    殷跃平; 朱继良; 杨胜元

    2010-01-01

    2010年6月28日,贵州关岭因突降暴雨发生高速远程滑坡,滑程约1.5km,体积约174.9万m3,两个村组被毁, 99人遇难.滑坡区位于西南地区常见的煤系地层区,上部为灰岩、白云岩,中部为相对较缓的砂岩地层,下部为页岩、泥岩地层,局部含煤,具有上硬下软的山体地质结构和上部富水下部隔水的水文地质结构,极易形成滑坡地质灾害.从地形上看,斜坡上陡下缓,形似"靴状地形",上部陡峭地形导致山体易于失稳,而中下部开阔伸展良好的沟谷提供了远程的运动条件,较大的势能向动能的转化,容易形成高速远程滑坡-碎屑流.6月27日和28日的降雨是触发此起特大灾害的主要原因,其24h降雨量达310mm,超过了当地近60a来的气象记录,分析表明,降雨产生的沟谷径流量是平时强降雨(100~150mm·d -1)的沟谷径流的2倍之上,一是在滑源区砂岩裂隙岩体中形成静水压力和渗透压力,触使滑坡的失稳下滑; 二是在沟谷中产生地表径流,为碎屑流远程流动形成饱水下垫面,导致了碎屑流流动距离和速度的显著增加.近年来随着极端强降雨等灾害性天气的重现期缩短,高速远程滑坡造成的群死群伤特大地质灾害在我国呈逐渐增加趋势,应加强对这种灾害类型的调查与防范,特别是要进行滑坡安全避让范围和逃逸速度的研究.

  13. Run-out Not a Geometrical Characteristic——Eleventh Comment on ISO 1101:2004%跳动不是几何特征——十一评ISO 1101:2004

    Institute of Scientific and Technical Information of China (English)

    倪新珉

    2007-01-01

    跳动实质上是一种几何误差测量方法,ISO1101:2004《产品几何技术规范(GPS)几何公差形状、方位、位置和跳动公差》表格1给出符号 、↑,用作轮廓面及其线素的几何公差公差代号中的几何特征符号,

  14. Reparación a las víctimas de dictaduras, conflictos armados y violencia política en sus componente de compensación, satisfacción, rehabilitación y no repetición (reparation for victims of dictatorships, armed conflicts and political violence in their components of compensation, satisfaction, rehabilitation, and non-repetition

    Directory of Open Access Journals (Sweden)

    Juan David Villa

    2015-01-01

    Full Text Available Encabezado de página SUSCRIPCIÓN Inicie sesión para verificar la suscripción USUARIO/A Nombre de usuario/a Contraseña No cerrar sesión NOTIFICACIONES Vista Suscribirse IDIOMA Escoge idioma CONTENIDO DE LA REVISTA Buscar Ámbito de la búsqueda Examinar Por número Por autor/a Por título Otras revistas TAMAÑO DE FUENTE Make font size smallerMake font size defaultMake font size larger INFORMACIÓN Para lectores/as Para autores/as Para bibliotecarios/as INICIO ACERCA DE INICIAR SESIÓN BUSCAR ACTUAL ARCHIVOS Inicio > Vol. 15, Núm. 1 (2015 >\tVilla REPARACIÓN A LAS VÍCTIMAS DE DICTADURAS, CONFLICTOS ARMADOS Y VIOLENCIA POLÍTICA EN SUS COMPONENTE DE COMPENSACIÓN, SATISFACCIÓN, REHABILITACIÓN Y NO REPETICIÓN Juan David Villa, Daniela Londoño Díaz, Daniela Barrera Machado Resumen Resumen: El presente texto segundo de dos entregas, realiza un acercamiento a las investigaciones realizadas en la pasada década y a comienzos de la presente sobre los procesos de reparación, en el marco de procesos de justicia transicional en países en procesos que van de la guerra a la paz y de la dictadura a la democracia. Se revisan investigaciones que versan sobre las consecuencias de los procesos de reparación y de transición en las víctimas, en la reconstrucción del tejido social, en la generación de procesos de reconciliación y la transformación del sujeto individual y colectivo. Abstract: This current text, which is the second of two issues, carries out an approach of investigations conducted in the past decade and at the beginning of the present decade on the reparation processes, within the context of transitional justice processes, in countries which are on the way to peace, and from dictatorship to democracy. We review research dealing with the consequences of the reparation and transition processes of victims, in the reconstruction of the social fabric, in the generation of reconciliation processes, and the transformation of the individual and collective subject.

  15. L-Band Radar Clutter Statistics for Terrain and Ice. Volume II. Appendices

    Science.gov (United States)

    1978-02-01

    11 i r 1 r i br Hi i "n "nr Iß JSRAGRAM rCtWfWrWWKrTÄiK AREA fir WORK UNIT NUMBERS Amendment Nr. P00002 Tech. Rqmt. Nr. NO32 nrr...o o o o Figure 60a. Cumuiacive Distribucion £or Mountain Mountain N 6.00 8.00 10.00 12.00 14.00 16.00 18.00 20.00 22.00 24.00...ftn TOTAL POINTS SAMPLES/RANGE RES ELEMENT: 2 SAMPLES/AZIMUTH RES ELEMENT: TOTAL SWATH WIDTH: 3^ OFFSET TO CENTER: 268 mm .run TEST AREA

  16. The Enigmatic Nature of the Israeli Legal System

    African Journals Online (AJOL)

    RV

    of 100 kilometres.12 Armadillo Aerospace has plans to develop a sub-orbital two- seater space ..... Clear international consensus on the definition of outer space has, however, not yet ...... act are restitution, satisfaction and non-repetition.191.

  17. 76 FR 27232 - Airworthiness Directives; Airbus Model A310 Series Airplanes

    Science.gov (United States)

    2011-05-11

    ..., 1979); and 3. Will not have a significant economic impact, positive or negative, on a substantial...) of this AD; or modification of the reinforcement angle runout in accordance with Airbus Service... reinforcement angle runout in accordance with Airbus Service Bulletin A310-53-2019, Revision 3, dated...

  18. 76 FR 42 - Airworthiness Directives; Airbus Model A310 Series Airplanes

    Science.gov (United States)

    2011-01-03

    ... Procedures (44 FR 11034, February 26, 1979); and 3. Will not have a significant economic impact, positive or...) of this AD; or modification of the reinforcement angle runout in accordance with Airbus Service... reinforcement angle runout in accordance with Airbus Service Bulletin A310-53-2019, Revision 3, dated...

  19. Advanced Triangulation Displacement Sensors

    Science.gov (United States)

    Poteet, Wade M.; Cauthen, Harold K.

    1996-01-01

    Advanced optoelectronic triangulation displacement sensors undergoing development. Highly miniaturized, more stable, more accurate, and relatively easy to use. Incorporate wideband electronic circuits suitable for real-time monitoring and control of displacements. Measurements expected to be accurate to within nanometers. In principle, sensors mass-produced at relatively low unit cost. Potential applications numerous. Possible industrial application in measuring runout of rotating shaft or other moving part during fabrication in "zero-defect" manufacturing system, in which measured runout automatically corrected.

  20. Advanced Triangulation Displacement Sensors

    Science.gov (United States)

    Poteet, Wade M.; Cauthen, Harold K.

    1996-01-01

    Advanced optoelectronic triangulation displacement sensors undergoing development. Highly miniaturized, more stable, more accurate, and relatively easy to use. Incorporate wideband electronic circuits suitable for real-time monitoring and control of displacements. Measurements expected to be accurate to within nanometers. In principle, sensors mass-produced at relatively low unit cost. Potential applications numerous. Possible industrial application in measuring runout of rotating shaft or other moving part during fabrication in "zero-defect" manufacturing system, in which measured runout automatically corrected.

  1. Dynamics of Focal Fibrillation Waves during Persistent Atrial Fibrillation.

    Science.gov (United States)

    Lanters, Eva A H; Allessie, Maurits A; DE Groot, Natasja M S

    2016-04-01

    The incidence and appearance of focal fibrillation waves on the right and left atrial epicardial surface were visualized during 10 seconds of persistent atrial fibrillation in a 71-year-old woman with valvular heart disease. The frequent, nonrepetitive, widespread, and capricious distribution of focal waves suggests that transmural conduction of fibrillation waves is most likely the mechanism underlying focal fibrillation waves.

  2. Gold-Collar Workers. ERIC Digest.

    Science.gov (United States)

    Wonacott, Michael E.

    The gold-collar worker has problem-solving abilities, creativity, talent, and intelligence; performs non-repetitive and complex work difficult to evaluate; and prefers self management. Gold-collar information technology workers learn continually from experience; recognize the synergy of teams; can demonstrate leadership; and are strategic thinkers…

  3. Phylogenetic placement of the spider genus Nephila (Araneae: Araneoidea) inferred from rRNA and MaSp1 gene sequences.

    Science.gov (United States)

    Pan, Hong-Chun; Zhou, Kai-Ya; Song, Da-Xiang; Qiu, Yang

    2004-03-01

    The family status of the genus Nephila, which belongs to Tetragnathidae currently but Araneidae formerly, was reexamined based on molecular phylogenetic analyses. In the present study, 12S and 18S rRNA gene fragments of eight species of spiders were amplified and sequenced. In addition, 3'-end partial cDNA of major ampullate spidroin-1 (MaSp1) gene of Argiope amoena was cloned and sequenced, and the 3'-end non-repetitive region's cDNA sequence of MaSp1 gene and the predicted amino acid sequence of C-terminal non-repetitive region of MaSp1 were aligned with some previously known sequences. The resulting phylogeny showed that Araneidae and Tetragnathidae are not a sister group in the superfamily Araneoidea, and the genus Nephila is closer to the genera of the family Araneidae rather than to those of Tetragnathidae. We suggest that the genus Nephila should be transferred back to Araneidae. Or the subfamily Nephilinae might be elevated to family level after it was redefined and redelimited. Furthermore, the study showed that 3'-end non-repetitive region's cDNA sequence of MaSp1 gene and C-terminal non-repetitive region's amino acid sequence of MaSp1 are useful molecular markers for phylogenetic analysis of spiders.

  4. 48 CFR 217.7303 - Solicitation provision.

    Science.gov (United States)

    2010-10-01

    ... information was obtained under other acquisitions); (3) The contract is for subsistence, clothing or textiles, fuels, or supplies purchased and used outside the United States; (4) The contracting officer determines...., nonrepetitive local purchases; or (5) The contracting officer determines that the exception at...

  5. BETTER PROJECT PLANNING AND CONTROL THROUGH THE USE OF SYSTEM ANALYSIS AND MANAGEMENT TECHNIQUES.

    Science.gov (United States)

    COOK, DESMOND L.

    THE COMBINED APPLICATION OF SYSTEM ANALYSIS AND MANAGEMENT TECHNIQUES IS DESCRIBED AS AN EFFECTIVE WAY TO ACHIEVE OPTIMUM RESULTS IN THE PLANNING AND EXECUTION OF PROJECTS IN THE FIELD OF EDUCATION. PROJECTS OF THIS TYPE ARE GENERALLY FINITE, COMPLEX, HOMOGENOUS, AND NONREPETITIVE. SYSTEM ANALYSIS OF A PROJECT INCLUDES ITS DISASSEMBLY INTO…

  6. Condition monitoring of multistage printing presses

    Science.gov (United States)

    Wang, W.; Golnaraghi, F.; Ismail, F.

    2004-03-01

    The main concern in printing quality in multistage presses is doubling. Doubling is caused by imperfections either within stages (units) or in links connecting different stages, mainly resulting from machine vibration, gear damage, and excessive run-out. In this paper, we propose new means for printing quality control via geared system health condition monitoring. The diagnosis is based on the signals acquired from inexpensive magnetic pickups. A new technique is developed to monitor the gear rotation synchronization among different stages in order to isolate possible sources of the doubling problem. A new approach is proposed to determine the gear run-out. Moreover, gear tooth damage detection is conducted using the beta kurtosis and the continuous wavelet transform based on the overall residual signal. The beta kurtosis of original signal average is also shown here to be useful in detecting excessive gear run-out. Test results from printing presses demonstrated the viability of the proposed methods.

  7. New Cutting Force Modeling Approach for Flat End Mill

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    A new mechanistic cutting force model for flat end milling using the instantaneous cutting force coefficients is proposed. An in-depth analysis shows that the total cutting forces can be separated into two terms: a nominal component independent of the runout and a perturbation component induced by the runout. The instantaneous value of the nominal component is used to calibrate the cutting force coefficients. With the help of the perturbation component and the cutting force coeffcients obtained above, the cutter runout is identified.Based on simulation and experimental results, the validity of the identification approach is demonstrated. The advantage of the proposed method lies in that the calibration performed with data of one cutting test under a specific regime can be applied for a great range of cutting conditions.

  8. A simple qualitative approach for mapping regional landslide susceptibility in the Faroe Islands

    Directory of Open Access Journals (Sweden)

    M.-P. J. Dahl

    2010-02-01

    Full Text Available The Faroe Islands in the North Atlantic Ocean are highly susceptible to landslides. Following recent landslide incidents, Jarðfeingi (Faroese Earth and Energy Directorate has pointed out, that the risk of human lives or of property being lost or affected by landslides may be increasing. This paper aims at presenting and testing a simple qualitative approach for mapping regional landslide susceptibility in the Faroe Islands, using few key parameters. The susceptibility model holds information about both landslide initiation areas and runout zones. Landslide initiation areas are determined from slope angle thresholds (25°–40° and soil cover data, while runout zones are delineated using the angle of reach approach taking into account the presence/absence of geological benches in the runout path, which has not been considered in earlier studies. Data input is obtained from a landslide database containing 67 debris flows throughout the Faroe Islands. Angle of reach values differ significantly with the presence/absence of geological benches in the runout path. Two values of angle of reach, 21.5° and 27.6°, are used for calculating runout zones. The landslide susceptibility model is tested in a study area at the town of Klaksvík in the northern part of the Faroe Islands. A map validation comparing predicted susceptibility zones with a validation-dataset of 87 actual landslides in the study area reveal that 69% and 92%, respectively, of actual landslide initiation areas and runout zones are correctly predicted. Moreover 87% of the actual landslides are included in the overall predicted landslide susceptibility areas.

  9. ANALYTICAL CHIP FORMATION MODEL OF MICRO-END-MILLING

    Institute of Scientific and Technical Information of China (English)

    LI Chengfeng; LAI Xinmin; LI Hongtao; PENG Linfa; NI Jun

    2008-01-01

    A new analytical chip formation model is proposed for micro-end-milling operations. The model calculates an instantaneous uncut chip thickness by considering the combination of exact trochoidal trajectory of the tool tip and tool run-out, while the simplified circular trajectory and the neglected run-out create negligible change in conventional-scale chip formation models. Newton-Raphson iterative method is employed during the calculation to obtain quadratic convergence. The proposed approach allows the calculation of instantaneous uncut chip thickness to be done accurately and rapidly, and the prediction accuracy of this model is also verified by comparing the simulation results to experimental cutting forces.

  10. Issues in the assessments of gravity mass flow hazard in the Storegga area off western Norwegian coast

    Science.gov (United States)

    Issler, D.; de Blasio, F.; Elverhøi, A.; Ilstad, T.; Bryn, P.; Lien, R.

    2003-04-01

    Statistical analysis of the lobes of the Storegga slide reveals a power-law dependence of the runout distance on the release volume. For small to moderate volumes, visco-plastic models with a (remoulded) yield strength of about 10 kPa reproduce this dependence quite well, in contrast to granular-friction models. However, either progressive wetting of the bottom shear layer or hydroplaning has to be invoked to explain the extreme runout distance and the sediment distribution of the largest slide phase. Preliminary estimates of the turbidite volume put severe constraints on the formation rate and density of the turbidity currents accompanying the slide.

  11. Prevalence of antibiotic resistance among Acinetobacter baumannii isolates from Aleppo, Syria.

    Science.gov (United States)

    Hamzeh, Abdul Rezzak; Al Najjar, Mona; Mahfoud, Maysa

    2012-10-01

    This study describes and analyzes Acinetobacter baumannii antibiotic susceptibly profile in Aleppo, Syria, thus providing vital information for guiding treatment of A baumannii infections. Two hundred sixty nonrepetitive A baumannii isolates were studied over 3.5 years. Resistance rates are at the higher end of globally reported levels. Newer cephalosporins and β-lactamase-resistant agents are becoming practically ineffective. Better activity is limited to carbapenems and colistin, which elicited the highest susceptibility levels.

  12. Construyendo Nuevos Tejidos Sociales a partir de las Memorias

    OpenAIRE

    Ayllón Yares, Gladys

    2017-01-01

    This research seeks to address the need for victims of the internal armed conflict in Peru to build a social fabric that allows them to live with dignity and to establish non-repetition of violence agreements. Within this framework, memory, for the victims, represents the tool that allows the construction of this fabric, because within the exercise of memory is the desire that the past not be repeated. This conception of memory that victims propose has been posed and developed by organizat...

  13. 工业机器人

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    2D YAG welding on non-linear trajectories with 3D camera seam tracker following for automotive applications,3D vision-based control on an industrial robot,A Flatness Based Design for Tracking Control of Pneumatic Muscle Actuators,A fuzzy dynamic uncertainty compensator for industrial robots,A graphical user interface for industrial robot programming in non-repetitive tasks……

  14. Post-traumatic Raynaud's phenomenon following volar plate injury.

    Science.gov (United States)

    Chodakiewitz, Yosef G; Daniels, Alan H; Kamal, Robin N; Weiss, Arnold-Peter C

    2014-04-01

    Post-traumatic Raynaud's phenomenon following non-penetrating or non-repetitive injury is rare. We report a case of Raynaud's phenomenon occurring in a single digit 3 months following volar plate avulsion injury. Daily episodes of painless pallor of the digit occurred for 1 month upon any exposure to cold, resolving with warm water therapy. Symptoms resolved after the initiation of hand therapy, splinting, and range-of- motion exercises.

  15. Synchronous Control Effort Minimized for Magnetic-Bearing-Supported Shaft

    Science.gov (United States)

    Brown, Gerald V.

    2001-01-01

    Various disturbances that are synchronous with the shaft speed can complicate radial magnetic bearing control. These include position sensor target irregularities (runout) and shaft imbalance. The method presented here allows the controller to ignore all synchronous harmonics of the shaft position input (within the closed-loop bandwidth) and to respond only to asynchronous motions. The result is reduced control effort.

  16. Hydroplaning and submarine debris flows

    Science.gov (United States)

    de Blasio, Fabio V.; Engvik, Lars; Harbitz, Carl B.; ElverhøI, Anders

    2004-01-01

    Examination of submarine clastic deposits along the continental margins reveals the remnants of holocenic or older debris flows with run-out distances up to hundreds of kilometers. Laboratory experiments on subaqueous debris flows, where typically one tenth of a cubic meter of material is dropped down a flume, also show high velocities and long run-out distances compared to subaerial debris flows. Moreover, they show the tendency of the head of the flow to run out ahead of the rest of the body. The experiments reveal the possible clue to the mechanism of long run-out. This mechanism, called hydroplaning, begins as the dynamic pressure at the front of the debris flow becomes of the order of the pressure exerted by the weight of the sediment. In such conditions a layer of water can intrude under the sediment with a lubrication effect and a decrease in the resistance forces between the sediment and the seabed. A physical-mathematical model of hydroplaning is presented and investigated numerically. The model is applied to both laboratory- and field-scale debris flows. Agreement with laboratory experiments makes us confident in the extrapolation of our model to natural flows and shows that long run-out distances can be naturally attained.

  17. Assessing landslide exposure in areas with limited landslide information

    NARCIS (Netherlands)

    Pellicani, R.; van Westen, C.J.; Spilotro, G.

    2014-01-01

    Landslide risk assessment is often a difficult task due to the lack of temporal data on landslides and triggering events (frequency), run-out distance, landslide magnitude and vulnerability. The probability of occurrence of landslides is often very difficult to predict, as well as the expected

  18. Optical alignment of electrodes on electrical discharge machines

    Science.gov (United States)

    Boissevain, A. G.; Nelson, B. W.

    1972-01-01

    Shadowgraph system projects magnified image on screen so that alignment of small electrodes mounted on electrical discharge machines can be corrected and verified. Technique may be adapted to other machine tool equipment where physical contact cannot be made during inspection and access to tool limits conventional runout checking procedures.

  19. Prolonged effect of Rosiglitazone one year after discontinuation

    DEFF Research Database (Denmark)

    Gram-Kampmann, Eva-Marie

    2015-01-01

    : This study is a continuation of the two-year study SDDS, where 371 patients were randomized to eight groups and treated with Insulin aspart three times daily or NPH insulin once daily, metformin or placebo and Rosiglitazone or placebo, respectively. During a 12-month run-out, use of insulin was continued...

  20. Laser Doppler interferometer for vibration of rotating curved surfaces

    Science.gov (United States)

    Wu, Giin-Yuan; Lee, Chih-Kung; Lin, San; Wakabayashi, Takenori; Ono, K.

    1999-10-01

    With the rapid advancement of today's ultra-high performance mechanical or mechatronic system such as magnetic or optical disk drives, improving metrology capabilities to examine the performance characteristics of these system are growing ever more important. The primary tested studied in this paper is an ultra-high precision ball-bearing spindle that possesses non-repeatable runout of less than 100nm. The metrology tool adopted is laser Doppler interferometer system that has Megahertz bandwidth and nanometer resolutions. Experimental data obtained clearly indicates that measuring vertical runout of a spindle motor is a straightforward process. However, a fundamental effect was identified, where the radial runout data was found to drift upward or downward with time, when using the laser Doppler system to measure the radial runout of ultra-high precision rotational systems whose surface profile is not flat. All of the underlying reasons that cause this undesirable effect were proposed and verified. Approaches that can be adopted to circumvent this apparent limitation on adopting the laser Doppler interferometer systems to measure rotational curved surface were implemented to further extend its application horizon. The experimental data realized and the application experience obtained were shown to further advance our measurement capabilities.

  1. Assessing Landslide Mobility Using GIS: Application to Kosrae, Micronesia

    Science.gov (United States)

    Reid, M. E.; Brien, D. L.; Godt, J.; Schmitt, R. G.; Harp, E. L.

    2015-12-01

    Deadly landslides are often mobile landslides, as exemplified by the disastrous landslide that occurred near Oso, Washington in 2014 killing 43. Despite this association, many landslide susceptibility maps do not identify runout areas. We developed a simple, GIS-based method for identifying areas potentially overrun by mobile slides and debris flows. Our method links three processes within a DEM landscape: landslide initiation, transport, and debris-flow inundation (from very mobile slides). Given spatially distributed shear strengths, we first identify initiation areas using an infinite-slope stability analysis. We then delineate transport zones, or regions of potential entrainment and/or deposition, using a height/length runout envelope. Finally, where these transport zones intersect the channel network, we start debris-flow inundation zones. The extent of inundation is computed using the USGS model Laharz, modified to include many debris-flow locations throughout a DEM. Potential debris-flow volumes are computed from upslope initiation areas and typical slide thicknesses. We applied this approach to the main island of Kosrae State, Federated States of Micronesia (FSM). In 2002, typhoon Chata'an triggered numerous landslides on the neighboring islands of Chuuk State, FSM, resulting in 43 fatalities. Using an infinite-slope stability model calibrated to the Chuuk event, we identified potential landslide initiation areas on Kosrae. We then delineated potential transport zones using a 20º runout envelope, based on runout observations from Chuuk. Potential debris-flow inundation zones were then determined using Laharz. Field inspections on Kosrae revealed that our resulting susceptibility map correctly classified areas covered by previous debris-flow deposits and did not include areas covered by fluvial deposits. Our map has the advantage of providing a visual tool to portray initiation, transport, and runout zones from mobile landslides.

  2. Parameterization of a numerical 2-D debris flow model with entrainment: a case study of the Faucon catchment, Southern French Alps

    Directory of Open Access Journals (Sweden)

    H. Y. Hussin

    2012-10-01

    Full Text Available The occurrence of debris flows has been recorded for more than a century in the European Alps, accounting for the risk to settlements and other human infrastructure that have led to death, building damage and traffic disruptions. One of the difficulties in the quantitative hazard assessment of debris flows is estimating the run-out behavior, which includes the run-out distance and the related hazard intensities like the height and velocity of a debris flow. In addition, as observed in the French Alps, the process of entrainment of material during the run-out can be 10–50 times in volume with respect to the initially mobilized mass triggered at the source area. The entrainment process is evidently an important factor that can further determine the magnitude and intensity of debris flows. Research on numerical modeling of debris flow entrainment is still ongoing and involves some difficulties. This is partly due to our lack of knowledge of the actual process of the uptake and incorporation of material and due the effect of entrainment on the final behavior of a debris flow. Therefore, it is important to model the effects of this key erosional process on the formation of run-outs and related intensities. In this study we analyzed a debris flow with high entrainment rates that occurred in 2003 at the Faucon catchment in the Barcelonnette Basin (Southern French Alps. The historic event was back-analyzed using the Voellmy rheology and an entrainment model imbedded in the RAMMS 2-D numerical modeling software. A sensitivity analysis of the rheological and entrainment parameters was carried out and the effects of modeling with entrainment on the debris flow run-out, height and velocity were assessed.

  3. Sequencing chromosome 5D of Aegilops tauschii and comparison with its allopolyploid descendant bread wheat (Triticum aestivum).

    Science.gov (United States)

    Akpinar, Bala A; Lucas, Stuart J; Vrána, Jan; Doležel, Jaroslav; Budak, Hikmet

    2015-08-01

    Flow cytometric sorting of individual chromosomes and chromosome-based sequencing reduces the complexity of large, repetitive Triticeae genomes. We flow-sorted chromosome 5D of Aegilops tauschii, the D genome donor of bread wheat and sequenced it by Roche 454 GS FLX platform to approximately 2.2x coverage. Repetitive sequences represent 81.09% of the survey sequences of this chromosome, and Class I retroelements are the prominent type, with a particular abundance of LTR/Gypsy superfamily. Nonrepetitive sequences were assembled to cover 17.76% of the total chromosome regions. Up to 6188 nonrepetitive gene loci were predicted to be encoded by the 5D chromosome. The numbers and chromosomal distribution patterns of tRNA genes suggest abundance in tRNA(L) (ys) and tRNA(M) (et) species, while the nonrepetitive assembly reveals tRNA(A) (la) species as the most abundant type. A comparative analysis of the genomic sequences of bread wheat and Aegilops chromosome 5D indicates conservation of gene content. Orthologous unique genes, matching Aegilops 5D sequences, numbered 3730 in barley, 5063 in Brachypodium, 4872 in sorghum and 4209 in rice. In this study, we provide a chromosome-specific view into the structure and organization of the 5D chromosome of Ae. tauschii, the D genome ancestor of bread wheat. This study contributes to our understanding of the chromosome-level evolution of the wheat genome and presents a valuable resource in wheat genomics due to the recent hybridization of Ae. tauschii genome with its tetraploid ancestor.

  4. Knowledge Management in Real Estate Consultancy Firms: Breaking through the Barriers

    Directory of Open Access Journals (Sweden)

    Yasmin Mohd Adnan

    2007-12-01

    Full Text Available Corporate knowledge is well accepted as a decisive asset in most countries worldwide, The know-how and expertise of the work-force is an important factor for the success of companies and strongly influences the effectiveness and efficiency of the business processes and their outcome. In real estate consultancy firms, knowledge management (KM is specifically relevant due to the knowledge intensive character of delivering the services to be rendered to clients, which call demand innovative and non-repetitive processes. However, there are barriers that need to be overcome so that the potentials of KM are capitalized.

  5. SNP detection for massively parallel whole-genome resequencing

    DEFF Research Database (Denmark)

    Li, Ruiqiang; Li, Yingrui; Fang, Xiaodong

    2009-01-01

    of this information was integrated into a single quality score for each base under Bayesian theory to measure the accuracy of consensus calling. We tested this methodology using a large-scale human resequencing data set of 36x coverage and assembled a high-quality nonrepetitive consensus sequence for 92......-genome or target region resequencing. Here, we have developed a consensus-calling and SNP-detection method for sequencing-by-synthesis Illumina Genome Analyzer technology. We designed this method by carefully considering the data quality, alignment, and experimental errors common to this technology. All...

  6. Establishment and Application of UFC-ACC Heat Transfer Coefficient Model

    Institute of Scientific and Technical Information of China (English)

    Tian-Liang Fu; Zhao-Dong Wang; Yong Li; Jia-Dong Li; Guo-Dong Wang

    2014-01-01

    Based on medium plate runout table ultra-fast cooling ( UFC)-accelerated cooling equipment ( ACC) system, a heat transfer coefficient model was constructed. Firstly, according to the measured data, heat transfer coefficients under different roll speed and water volume were calculated by using an inverse heat conduction method. Secondly, a monofactorial heat transfer coefficient calculation formula was obtained. Finally, the heat transfer coefficient model based on medium plate runout table UFC-ACC system was constructed by intercept function, slope function, interaction influence function and linear or nonlinear influencing factors. The precision of these models was validated by comparing model prediction value with measured data, and the results were in good agreement with practical needs, and the average deviation was less than 5%.

  7. Semiautomated object-based classification of rain-induced landslides with VHR multispectral images on Madeira Island

    Science.gov (United States)

    Heleno, Sandra; Matias, Magda; Pina, Pedro; Sousa, António Jorge

    2016-04-01

    A method for semiautomated landslide detection and mapping, with the ability to separate source and run-out areas, is presented in this paper. It combines object-based image analysis and a support vector machine classifier and is tested using a GeoEye-1 multispectral image, sensed 3 days after a major damaging landslide event that occurred on Madeira Island (20 February 2010), and a pre-event lidar digital terrain model. The testing is developed in a 15 km2 wide study area, where 95 % of the number of landslides scars are detected by this supervised approach. The classifier presents a good performance in the delineation of the overall landslide area, with commission errors below 26 % and omission errors below 24 %. In addition, fair results are achieved in the separation of the source from the run-out landslide areas, although in less illuminated slopes this discrimination is less effective than in sunnier, east-facing slopes.

  8. Automated object-based classification of rain-induced landslides with VHR multispectral images in Madeira Island

    Science.gov (United States)

    Heleno, S.; Matias, M.; Pina, P.; Sousa, A. J.

    2015-09-01

    A method for semi-automatic landslide detection, with the ability to separate source and run-out areas, is presented in this paper. It combines object-based image analysis and a Support Vector Machine classifier on a GeoEye-1 multispectral image, sensed 3 days after the major damaging landslide event that occurred in Madeira island (20 February 2010), with a pre-event LIDAR Digital Elevation Model. The testing is developed in a 15 km2-wide study area, where 95 % of the landslides scars are detected by this supervised approach. The classifier presents a good performance in the delineation of the overall landslide area. In addition, fair results are achieved in the separation of the source from the run-out landslide areas, although in less illuminated slopes this discrimination is less effective than in sunnier east facing-slopes.

  9. The role of fluid viscosity in an immersed granular collapse

    Directory of Open Access Journals (Sweden)

    Yang Geng Chao

    2017-01-01

    Full Text Available Instabilities of immersed slopes and cliffs can lead to catastrophic events that involve a sudden release of huge soil mass. The scaled deposit height and runout distance are found to follow simple power laws when a granular column collapses on a horizontal plane. However, if the granular column is submerged in a fluid, the mobility of the granular collapse due to high inertia effects will be reduced by fluid-particle interactions. In this study, the effects of fluid viscosity on granular collapse is investigated qualitatively by adopting a numerical approach based on the coupled lattice Boltzmann method (LBM and discrete element method (DEM. It is found that the granular collapse can be dramatically slowed down due to the presence of viscous fluids. For the considered granular configuration, when the fluid viscosity increases. the runout distance decreases and the final deposition shows a larger deposit angle.

  10. Dynamics of the Bingham Canyon Mine landslides from seismic signal analysis

    Science.gov (United States)

    Hibert, Clément; Ekström, Göran; Stark, Colin P.

    2014-07-01

    Joint interpretation of long- and short-period seismic signals generated by landslides sheds light on the dynamics of slope failure, providing constraints on landslide initiation and termination and on the main phases of acceleration and deceleration. We carry out a combined analysis of the seismic signals generated by two massive landslides that struck the Bingham Canyon Mine pit on 10 April 2013. Inversion of the long-period waveforms yields time series for the bulk landslide forces and momenta, from which we deduce runout trajectories consistent with the deposit morphology. Comparing these time series with the short-period seismic data, we are able to infer when and where major changes take place in landslide momentum along the runout path. This combined analysis points to a progressive fracturing of the masses during acceleration indicates that deceleration starts the moment they reach the pit floor and suggests that the bulk movement is stopped by a topographic barrier.

  11. Investigation of Effect of Operating Parameters of A CNC Cylindrical Grinding Machine on Geometric Dimensioning and Tolerancing

    Directory of Open Access Journals (Sweden)

    Jayalakshmi

    2014-03-01

    Full Text Available Machining processes are met with dimensional and geometrical variations in a product during machining operation. The amount of variation needs to be more strictly defined for accurately machined parts. Geometric dimensioning and tolerancing (GD&T definition provides the precision required for allowing manufacturing of most economical parts. Crankshaft flange is required to be machined with higher degree of precision. If geometrical accuracies are not met the crankshaft-flywheel assembly will cause wear, unbalance and vibration, leading to poor functionality. The face of crankshaft flange is evaluated for geometric tolerances- flatness and runout. A two level three factor factorial model is designed and analyzed on Minitab 16 software to identify the most affecting machining parameter among speed, feed and depth of cut on face flatness and face runout.

  12. ECCS flow verification to support transient analysis

    Energy Technology Data Exchange (ETDEWEB)

    Kovach, C.; Jacobs, R.H.; Ballard, J.E. [Commonwealth Edison Co., Chicago, IL (United States). Nuclear Fuel Services Dept.

    1994-12-31

    The RETRAN code has been used to develop a model of the Emergency Core Cooling System (ECCS). The model was developed in order to provide conservative injection flow data to be used in various LOCA and non-LOCA analyses and evaluations and to ensure that ECCS pump runout does not occur. The analyses were also needed in order to address a number of ECCS performance issues identified by Westinghouse. These issues include how previous analyses modeled miniflow, RCP seal injection, ECCS branch line resistance, pump suction boost during recirculation, injection line flow imbalances, and, of particular importance, ECCS flow measurement inaccuracies. In turn, these issues directly impact pump runout concerns, Technical Specification verification, and ECCS injection flow during transient conditions. The RETRAN ECCS model has proven to be quite versatile, easy to use, and requires only minimal information about the physical construction and performance of the ECCS system.

  13. Cost Estimate for Gun Liner Emplacement

    Science.gov (United States)

    2011-08-01

    forge to near net outer diameter shape: 85-in long 3. Heat treat: quench and temper 4. Straighten to 0.005 in runout 5. Stress relieve 6. Grind ...steady rest 7. Cylindrically grind outer diameter (tapered) 8. Gun drill breech 9. Gun drill barrel inner diameter Detonation Velocity, Vd Gun...1.25-in inner diameter. Electrochemical machining (ECM) is already being employed to rifle M242 steel barrels by Alliant Techsystems (ATK). With this

  14. A comparative study of precision finishing of rebuild engine valve faces using micro-grinding and ECH

    OpenAIRE

    Singh, Harpreet; Jain, Pramod Kumar

    2015-01-01

    This paper presents a comparative analysis of process performance of micro-grinding and electrochemical honing, with the aim to achieve higher precision and surface quality of rebuild surfaces of the engine valve face. The discarded engine valve face was rebuilt using plasma transferred arc cladding technique and its surface finish was evaluated in terms of average roughness and maximum roughness value. The improvement in profile error and total run-out were used to evaluate the optimum proce...

  15. Upward-looking L-band FMCW radar for snow cover monitoring

    OpenAIRE

    2014-01-01

    Forecasting snow avalanche danger in mountainous regions is of major importance for the protection of infrastructure in avalanche run-out zones. Inexpensive measurement devices capable of measuring snow height and layer properties in avalanche starting zones may help to improve the quality of risk assessment. We present a low-cost L-band frequency modulated continuous wave radar system (FMCW) in upward-looking configuration. To monitor the snowpack evolution, the radar system was deployed in ...

  16. EDDA: integrated simulation of debris flow erosion, deposition and property changes

    OpenAIRE

    Chen, H. X.; Zhang, L. M.

    2014-01-01

    Debris flow material properties change during the initiation, transportation and deposition processes, which influences the runout characteristics of the debris flow. A quasi-three-dimensional depth-integrated numerical model, EDDA, is presented in this paper to simulate debris flow erosion, deposition and induced material property changes. The model considers changes in debris flow density, yield stress and dynamic viscosity during the flow process. The yie...

  17. EDDA 1.0: integrated simulation of debris flow erosion, deposition and property changes

    OpenAIRE

    Chen, H. X.; Zhang, L. M.

    2015-01-01

    Debris flow material properties change during the initiation, transportation and deposition processes, which influences the runout characteristics of the debris flow. A quasi-three-dimensional depth-integrated numerical model, EDDA (Erosion–Deposition Debris flow Analysis), is presented in this paper to simulate debris flow erosion, deposition and induced material property changes. The model considers changes in debris flow density, yield stress and dynamic viscosity during ...

  18. Development of Cooling Process Control Technique in Hot Strip Mill

    Institute of Scientific and Technical Information of China (English)

    HAN Bin; LIU Xiang-hua; WANG Guo-dong; SHE Guang-fu

    2005-01-01

    In order to ensure required mechanical properties of steel strip, various innovations in the cooling process control on the run-out table of a hot strip mill were actively promoted. The recent progress of process mathematical model and the new cooling strategy and equipment were discussed. The computer control system of high performance was introduced. The development trend in cooling process control was given.

  19. RATIONALE OF THE EVALUATION AND SELECTION OF KINEMATIC AND TRIBOLOGICAL CHARACTERISTICS OF THE SYSTEM «PINION – GEAR RACK» OF COLD-PILGERING MILLS

    Directory of Open Access Journals (Sweden)

    T. M. Kadilnikova

    2014-02-01

    Full Text Available Purpose. During operation of cold-pilgering mills rotation of the shafts is carried out by means of pinion gears being in meshing with stationary gear racks, which is accompanied by various tribological defects, that can be avoided during the detailed investigation and justification of selection and evaluation of kinematic and tribological characteristics of the system "pinion - gear rack". Methodology. Runout occurs as a consequence of increased friction and depends on the material hardness of which pinions and toothed racks are manufactured, their thermal treatment, selection of correct lubrication, insufficient oil purity and its untimely change, gears overload and other factors. To assess the runout of tribological pair cogs "pinion - gear rack" of the cold-pilgering mills we will use a system of differential equations of the first order. Using the solution of this system under the given conditions, it is possible to obtain relations for kinematic and tribological parameters. Findings. Relations for the durability, runout, sliding speed, and length of the line of the tribological pair "pinion - gear rack" contact are obtained. They provide high indicators of runout and durability of the system with minimum weight and overall dimensions of the design, which is an important factor to increase efficiency of cold-pilgering mills. Originality. The analysis of the relations, which was obtained to identify durability, wear, sliding speed, and the length of the line of the tribological pair "pinion - gear rack" contact allows you to choose for cold-pilgering mills special pinions with the design parameters, which optimally satisfy the technological conditions of rolling. Practical value. Analytical determination of the slip velocity for tribological pair makes it possible to adjust the technical process of cold-pilgering mills and to make constructive changes in the system of "pinion - gear rack" in order to increase its wear resistance.

  20. Motion of rock masses on slope

    Directory of Open Access Journals (Sweden)

    Urška Petje

    2006-12-01

    Full Text Available This paper shows the different ways of how rock masses (stones, rocks, and blocks move along slopes and for each different way of motion (free fall, bouncing, rolling, sliding, slowing down, lubrication, fluidizationadequatedynamicequationsaregiven.Knowingthe kinematics and dynamics of travelling rock masses is necessary for mathematical modeling of motion and by this an assessment of maximal possible rockfall runout distances as an example of a sudden and hazardeous natural phenomenon, threatening man and his property, especially in the natural environment.

  1. Development of a Nonlinear Cumulative Fatigue Damage Methodology for Aircraft Engine Components under Multiaxial Loadings

    Science.gov (United States)

    2007-04-01

    fatigue damage accumulation under a variety of loading conditions. These models are, for the most part, empirical approaches that have relied little on...elastic-plastic stresses listed in this table represent the surface stresses at maximum and minimum loads as determined by an elastic-plastic finite...Torsion,Load Control • R=-1 .Torsion.Strain Control © R-0,Torsion,Strain Control ■ Proportional • R=-1 .Torsion,Load Control A Runout ■ \\ n 0 X

  2. Comparative Analysis of Three Fretting Fatigue Fixtures (Preprint)

    Science.gov (United States)

    2006-02-01

    involving thresholds for long lives or crack growth rate calculations for shorter lives. Knockdown factors must be determined empirically , and are...specimen. It can be machined out of an unfailed side of the specimen or from both sides of an interrupted or runout specimen. The trailing edge of...work have been previously documented [4,6,9]. Conditions (shown in Table 1) were selected from available data to facilitate comparison of the

  3. Recent catastrophic landslides and mitigation in China

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Increasing population density and development of mountainous terrain have brought human settlements within reach of landslide hazards.In recent years,due to the shortening of return period for severe natural events such as heavy rainfall,snowline retreating,great earthquake together with human activities,catastrophic landslides happened more frequently than before,resulting in large-scale casualties due to the increasing occurrences of rapid long-runout rock avalanches,especially in China.This paper present...

  4. Influence of snow-cover properties on avalanche dynamics

    Science.gov (United States)

    Steinkogler, W.; Sovilla, B.; Lehning, M.

    2012-04-01

    Snow avalanches with the potential of reaching traffic routes and settlements are a permanent winter threat for many mountain communities. Snow safety officers have to take the decision whether to close a road, a railway line or a ski slope. Those decisions are often very difficult as they demand the ability to interpret weather forecasts, to establish their implication for the stability and the structure of the snow cover and to evaluate the influence of the snow cover on avalanche run-out distances. In the operational programme 'Italy-Switzerland, project STRADA' we focus on the effects of snow cover on avalanche dynamics, and thus run-out distance, with the aim to provide a better understanding of this influence and to ultimately develop tools to support snow safety officers in their decision process. We selected five avalanches, measured at the Vallée de la Sionne field site, with similar initial mass and topography but different flow dynamics and run-out distances. Significant differences amongst the individual avalanches could be observed for front and internal velocities, impact pressures, flow regimes, deposition volumes and run-out distances. For each of these avalanches, the prevailing snow conditions at release were reconstructed using field data from local snowpits or were modeled with SNOWPACK. Combining flow dynamical data with snow cover properties shows that erodible snow depth, snow density and snow temperature in the snow pack along the avalanche track are among the decisive variables that appear to explain the observed differences. It is further discussed, how these influencing factors can be quantified and used for improved predictions of site and time specific avalanche hazard.

  5. Recent changes in avalanche activity in the French Alps and their links with climatic drivers: an overview

    OpenAIRE

    Eckert, N.; Lavigne, A.; Castebrunet, H.; Giraud, G.; Naaim, M.

    2013-01-01

    International audience; This paper synthetizes our ongoing work on relations between natural avalanche activity and climate change in the French Alps and subregions. Firm results mainly concern occurrences, runout altitudes and high return period avalanches on long time scales (averages over “full” winters and winter-spring sub-seasons) since ~1950. Work in progress concerns extrapolation under future climate, shorter time scales (avalanche cycles), and more generally risk assessment under un...

  6. Debris flow relationships in the Central Spanish Pyrenees

    OpenAIRE

    Beguería, S.; A. Lorente; Garcia-Ruiz, J. M.

    2007-01-01

    Debris flows represent the most active geomorphic risk in mountainous areas, affecting infrastructures, human settlements and touristic resorts (Takahashi et al., 1981). For this reason, much effort has been put in assessing where debris flows occur and ranking the factors that trigger them, but also in defining two essential parameters in establishing debris flow hazards: what is the distance travelled by debris flows (especially the runout distance), and what is the volume of material carri...

  7. Vulnerabilities to Rock-Slope Failure Impacts from Christchurch, NZ Case History Analysis

    Science.gov (United States)

    Grant, A.; Wartman, J.; Massey, C. I.; Olsen, M. J.; Motley, M. R.; Hanson, D.; Henderson, J.

    2015-12-01

    Rock-slope failures during the 2010/11 Canterbury (Christchurch), New Zealand Earthquake Sequence resulted in 5 fatalities and caused an estimated US$400 million of damage to buildings and infrastructure. Reducing losses from rock-slope failures requires consideration of both hazard (i.e. likelihood of occurrence) and risk (i.e. likelihood of losses given an occurrence). Risk assessment thus requires information on the vulnerability of structures to rock or boulder impacts. Here we present 32 case histories of structures impacted by boulders triggered during the 2010/11 Canterbury earthquake sequence, in the Port Hills region of Christchurch, New Zealand. The consequences of rock fall impacts on structures, taken as penetration distance into structures, are shown to follow a power-law distribution with impact energy. Detailed mapping of rock fall sources and paths from field mapping, aerial lidar digital elevation model (DEM) data, and high-resolution aerial imagery produced 32 well-constrained runout paths of boulders that impacted structures. Impact velocities used for structural analysis were developed using lumped mass 2-D rock fall runout models using 1-m resolution lidar elevation data. Model inputs were based on calibrated surface parameters from mapped runout paths of 198 additional boulder runouts. Terrestrial lidar scans and structure from motion (SfM) imagery generated 3-D point cloud data used to measure structural damage and impacting boulders. Combining velocity distributions from 2-D analysis and high-precision boulder dimensions, kinetic energy distributions were calculated for all impacts. Calculated impact energy versus penetration distance for all cases suggests a power-law relationship between damage and impact energy. These case histories and resulting fragility curve should serve as a foundation for future risk analysis of rock fall hazards by linking vulnerability data to the predicted energy distributions from the hazard analysis.

  8. Debris flow hazard modelling on medium scale: Valtellina di Tirano, Italy

    OpenAIRE

    J. Blahut; P. Horton; S. Sterlacchini; Jaboyedoff, M.

    2010-01-01

    Debris flow hazard modelling at medium (regional) scale has been subject of various studies in recent years. In this study, hazard zonation was carried out, incorporating information about debris flow initiation probability (spatial and temporal), and the delimitation of the potential runout areas. Debris flow hazard zonation was carried out in the area of the Consortium of Mountain Municipalities of Valtellina di Tirano (Central Alps, Italy). The complexity of the phenomenon, the scale of th...

  9. Rapid motions of free-surface avalanches down curved and twisted channels and their numerical simulation.

    Science.gov (United States)

    Pudasaini, Shiva P; Wang, Yongqi; Hutter, Kolumban

    2005-07-15

    This paper presents a new model and discussions about the motion of avalanches from initiation to run-out over moderately curved and twisted channels of complicated topography and its numerical simulations. The model is a generalization of a well established and widely used depth-averaged avalanche model of Savage & Hutter and is published with all its details in Pudasaini & Hutter (Pudasaini & Hutter 2003 J. Fluid Mech. 495, 193-208). The intention was to be able to describe the flow of a finite mass of snow, gravel, debris or mud, down a curved and twisted corrie of nearly arbitrary cross-sectional profile. The governing equations for the distribution of the avalanche thickness and the topography-parallel depth-averaged velocity components are a set of hyperbolic partial differential equations. They are solved for different topographic configurations, from simple to complex, by applying a high-resolution non-oscillatory central differencing scheme with total variation diminishing limiter. Here we apply the model to a channel with circular cross-section and helical talweg that merges into a horizontal channel which may or may not become flat in cross-section. We show that run-out position and geometry depend strongly on the curvature and twist of the talweg and cross-sectional geometry of the channel, and how the topography is shaped close to run-out zones.

  10. Numerical modelling of propagation of landslides using SPH

    Science.gov (United States)

    Montull, Carlos; Pastor, Manuel; Springman, Sarah

    2015-04-01

    Landslides cause severe economic damage and a large number of casualties every year around the world. Engineers and geologists need to understand and predict their properties, such as velocity, depth and run out distance. In addition to experience gained on similar cases, predictions require the application of mathematical, constitutive/rheological and numerical models. Different models are currently used to simulate long run-out landslides in order to elaborate hazard maps. Among the available alternatives, depth integrated models present a reasonable compromise between computational cost and accuracy. The purpose of this paper is to apply the SPH depth integrated model, together with suitable rheological laws, to analize fast landslides. We will present the results obtained with the code Geoflow_SPH to three selected cases: (i) The Frank avalanche, (ii) the Cougar Hill flowslide and (iii) the Sham Tseng debris flow. The results of the simulations include estimations of fundamental aspects of the problem, such as the path followed by the sliding mass, the shape of the run-out area, the maximum run-out, the depth of the final deposit, the pore pressure evolution and the speed evolution of the landslide.

  11. Debris flow characteristics and relationships in the Central Spanish Pyrenees

    Directory of Open Access Journals (Sweden)

    A. Lorente

    2003-01-01

    Full Text Available Unconfined debris flows (i.e. not in incised channels are one of the most active geomorphic processes in mountainous areas. Since they can threaten settlements and infrastructure, statistical and physically based procedures have been developed to assess the potential for landslide erosion. In this study, information on debris flow characteristics was obtained in the field to define the debris flow runout distance and to establish relationships between debris flow parameters. Such relationships are needed for building models which allow us to improve the spatial prediction of debris flow hazards. In general, unconfined debris flows triggered in the Flysch Sector of the Central Spanish Pyrenees are of the same order of magnitude as others reported in the literature. The deposition of sediment started at 17.8°, and the runout distance represented 60% of the difference in height between the head of the landslide and the point at which deposition started. The runout distance was relatively well correlated with the volume of sediment.

  12. Concepts and parameterisation of Perla and FLM model using Flow-R for debris flow

    Science.gov (United States)

    Horton, P.; Jaboyedoff, M.; Rudaz, B.

    2012-04-01

    The Flow-R software was built to allow regional debris flow susceptibility assessment. It uses propagation algorithms such as the friction model from Perla and friction-limited models (FLM). By using concepts from both models, a methodology is proposed to evaluate the friction angle and mass-to-drag ratio based on the maximum velocity estimation for debris flows, and on the observed runout on the debris fan. The goal is to use the energy line concept, the debris fan slope, and the runout on the latter, to estimate the friction angle, the Mass to Drag ratio and maximum flow velocity for a given debris flow event and specific conditions of a catchment. A relation between those parameters themselves and between them and the observed characteristics of the flow (runout, speed of flow, viscosity, thickness) is established. The sensitivity of the Flow-R model is tested on two real cases and a theoretical topography for both model types. The importance of the friction angle, relative to M/D, is established. It demonstrates that the FLM model gives results similar to the Perla model, and is useful to determine the friction angle and M/D parameters on debris fan topography, using known events as calibration for each case. Those parameters can then be used as input for local hazard simulation and prediction. In addition, using a broad set of parameters instead of of an ideal one, inducing different propagation results, is proposed for debris flow hazard mapping and assessment.

  13. Bayesian inference in mass flow simulations - from back calculation to prediction

    Science.gov (United States)

    Kofler, Andreas; Fischer, Jan-Thomas; Hellweger, Valentin; Huber, Andreas; Mergili, Martin; Pudasaini, Shiva; Fellin, Wolfgang; Oberguggenberger, Michael

    2017-04-01

    Mass flow simulations are an integral part of hazard assessment. Determining the hazard potential requires a multidisciplinary approach, including different scientific fields such as geomorphology, meteorology, physics, civil engineering and mathematics. An important task in snow avalanche simulation is to predict process intensities (runout, flow velocity and depth, ...). The application of probabilistic methods allows one to develop a comprehensive simulation concept, ranging from back to forward calculation and finally to prediction of mass flow events. In this context optimized parameter sets for the used simulation model or intensities of the modeled mass flow process (e.g. runout distances) are represented by probability distributions. Existing deterministic flow models, in particular with respect to snow avalanche dynamics, contain several parameters (e.g. friction). Some of these parameters are more conceptual than physical and their direct measurement in the field is hardly possible. Hence, parameters have to be optimized by matching simulation results to field observations. This inverse problem can be solved by a Bayesian approach (Markov chain Monte Carlo). The optimization process yields parameter distributions, that can be utilized for probabilistic reconstruction and prediction of avalanche events. Arising challenges include the limited amount of observations, correlations appearing in model parameters or observed avalanche characteristics (e.g. velocity and runout) and the accurate handling of ensemble simulations, always taking into account the related uncertainties. Here we present an operational Bayesian simulation framework with r.avaflow, the open source GIS simulation model for granular avalanches and debris flows.

  14. Influences of Sediment Viscosity and Bed Slope on Transport and Deposition Characteristics of Debris flow in Flume Experiments

    Science.gov (United States)

    Eu, Song; Li, Qiwen; Lee, Eunjai; Im, Sangjun

    2017-04-01

    Debris flow is a rapid flow of soil-water mixture along a confined channel. Implementing mitigation structures against debris flow, such as debris flow barrier or flexible net, is the widely used mitigation strategy to prevent the debris flow hazard. To design those structures enough to endure debris flow events, accurate estimation of flow behavior and hazardous area of debris flow is necessary. In this study, we conducted the small-scale flume experiments to analyze flow behavior and corresponding deposit characteristics according to the slope conditions of flume and viscosity of sediment mixture. In terms of flow characteristics of debris mixtures, there was a positive correlation between flow velocity and flume inclination while slower velocity was observed in higher viscosity of mixture. Results of flow depth, however, showed no significant difference along variation of flume angles and mixture viscosity. The deposit characteristics, including runout length and spreading width, showed a positive correlation with approaching flow velocity. The larger runout length and deposit width were observed in higher flow velocity, and runout length was more sensitive to the change of flow velocity compared to spreading width. (This study was carried out with the support of ´R&D Program for Forestry Technology (Project No. S211316L020110)´ provided by Korea Forest Service.)

  15. Origin of a folded repeat protein from an intrinsically disordered ancestor

    Science.gov (United States)

    Zhu, Hongbo; Sepulveda, Edgardo; Hartmann, Marcus D; Kogenaru, Manjunatha; Ursinus, Astrid; Sulz, Eva; Albrecht, Reinhard; Coles, Murray; Martin, Jörg; Lupas, Andrei N

    2016-01-01

    Repetitive proteins are thought to have arisen through the amplification of subdomain-sized peptides. Many of these originated in a non-repetitive context as cofactors of RNA-based replication and catalysis, and required the RNA to assume their active conformation. In search of the origins of one of the most widespread repeat protein families, the tetratricopeptide repeat (TPR), we identified several potential homologs of its repeated helical hairpin in non-repetitive proteins, including the putatively ancient ribosomal protein S20 (RPS20), which only becomes structured in the context of the ribosome. We evaluated the ability of the RPS20 hairpin to form a TPR fold by amplification and obtained structures identical to natural TPRs for variants with 2–5 point mutations per repeat. The mutations were neutral in the parent organism, suggesting that they could have been sampled in the course of evolution. TPRs could thus have plausibly arisen by amplification from an ancestral helical hairpin. DOI: http://dx.doi.org/10.7554/eLife.16761.001 PMID:27623012

  16. Sequencing of BAC pools by different next generation sequencing platforms and strategies

    Directory of Open Access Journals (Sweden)

    Scholz Uwe

    2011-10-01

    Full Text Available Abstract Background Next generation sequencing of BACs is a viable option for deciphering the sequence of even large and highly repetitive genomes. In order to optimize this strategy, we examined the influence of read length on the quality of Roche/454 sequence assemblies, to what extent Illumina/Solexa mate pairs (MPs improve the assemblies by scaffolding and whether barcoding of BACs is dispensable. Results Sequencing four BACs with both FLX and Titanium technologies revealed similar sequencing accuracy, but showed that the longer Titanium reads produce considerably less misassemblies and gaps. The 454 assemblies of 96 barcoded BACs were improved by scaffolding 79% of the total contig length with MPs from a non-barcoded library. Assembly of the unmasked 454 sequences without separation by barcodes revealed chimeric contig formation to be a major problem, encompassing 47% of the total contig length. Masking the sequences reduced this fraction to 24%. Conclusion Optimal BAC pool sequencing should be based on the longest available reads, with barcoding essential for a comprehensive assessment of both repetitive and non-repetitive sequence information. When interest is restricted to non-repetitive regions and repeats are masked prior to assembly, barcoding is non-essential. In any case, the assemblies can be improved considerably by scaffolding with non-barcoded BAC pool MPs.

  17. Molecular identification and characterization of clustered regularly interspaced short palindromic repeats (CRISPRs) in a urease-positive thermophilic Campylobacter sp. (UPTC).

    Science.gov (United States)

    Tasaki, E; Hirayama, J; Tazumi, A; Hayashi, K; Hara, Y; Ueno, H; Moore, J E; Millar, B C; Matsuda, M

    2012-02-01

    Novel clustered regularly-interspaced short palindromic repeats (CRISPRs) locus [7,500 base pairs (bp) in length] occurred in the urease-positive thermophilic Campylobacter (UPTC) Japanese isolate, CF89-12. The 7,500 bp gene loci consisted of the 5'-methylaminomethyl-2-thiouridylate methyltransferase gene, putative (P) CRISPR associated (p-Cas), putative open reading frames, Cas1 and Cas2, leader sequence region (146 bp), 12 CRISPRs consensus sequence repeats (each 36 bp) separated by a non-repetitive unique spacer region of similar length (26-31 bp) and the phosphatidyl glycerophosphatase A gene. When the CRISPRs loci in the UPTC CF89-12 and five C. jejuni isolates were compared with one another, these six isolates contained p-Cas, Cas1 and Cas2 within the loci. Four to 12 CRISPRs consensus sequence repeats separated by a non-repetitive unique spacer region occurred in six isolates and the nucleotide sequences of those repeats gave approximately 92-100% similarity with each other. However, no sequence similarity occurred in the unique spacer regions among these isolates. The putative σ(70) transcriptional promoter and the hypothetical ρ-independent terminator structures for the CRISPRs and Cas were detected. No in vivo transcription of p-Cas, Cas1 and Cas2 was confirmed in the UPTC cells.

  18. Full-length minor ampullate spidroin gene sequence.

    Directory of Open Access Journals (Sweden)

    Gefei Chen

    Full Text Available Spider silk includes seven protein based fibers and glue-like substances produced by glands in the spider's abdomen. Minor ampullate silk is used to make the auxiliary spiral of the orb-web and also for wrapping prey, has a high tensile strength and does not supercontract in water. So far, only partial cDNA sequences have been obtained for minor ampullate spidroins (MiSps. Here we describe the first MiSp full-length gene sequence from the spider species Araneus ventricosus, using a multidimensional PCR approach. Comparative analysis of the sequence reveals regulatory elements, as well as unique spidroin gene and protein architecture including the presence of an unusually large intron. The spliced full-length transcript of MiSp gene is 5440 bp in size and encodes 1766 amino acid residues organized into conserved nonrepetitive N- and C-terminal domains and a central predominantly repetitive region composed of four units that are iterated in a non regular manner. The repeats are more conserved within A. ventricosus MiSp than compared to repeats from homologous proteins, and are interrupted by two nonrepetitive spacer regions, which have 100% identity even at the nucleotide level.

  19. Mosaic evolution of silk genes in Aliatypus trapdoor spiders (mygalomorphae, antrodiaetidae).

    Science.gov (United States)

    Starrett, James; Hayashi, Cheryl Y

    2013-04-01

    Spider silk genes are composed mostly of repetitive sequence that is flanked by non-repetitive terminal regions. Inferences about the evolutionary processes that influenced silk genes have largely been made from analyses using distantly related taxa and ancient silk gene duplicates. These studies have relied on comparisons across the conserved non-repetitive terminal regions to determine orthologous and paralogous relationships, as well as the influence of selection on silk genes. While the repetitive region heavily influences silk fiber mechanical properties, few molecular evolutionary analyses have been conducted on this region due to difficulty in determining homology. Here, we sample internal repetitive and carboxy terminal regions from all extant species of the trapdoor spider genus, Aliatypus. Aliatypus spiders are highly dispersal limited and rely on their silk lined burrow for protection. We determine positional homology across species for the carboxy terminal regions and relative positional homology for the internal repetitive regions. Gene trees based on each of these regions are in good agreement with the Aliatypus species tree, which indicates we sampled single spidroin orthologs in each species. In addition, we find that purifying selection and concerted evolution have acted to conserve Aliatypus spidroin internal repetitive regions. In contrast, selection testing identifies evidence of sites that evolved under positive selection and amino acid replacements that result in radical physicochemical changes in the carboxy terminal region. These findings indicate that comparison of spidroin orthologs across a comprehensive sample of congenerics reveal molecular evolutionary patterns obscured from studies using higher-level sampling of silk encoding genes.

  20. Litigating reproductive health rights in the Inter-American System: what does a winning case look like?

    Science.gov (United States)

    O'Connell, Ciara

    2014-12-11

    Remedies and reparation measures emerging from the Inter-American System of Human Rights in reproductive health cases have consistently highlighted the need to develop, and subsequently implement, non-repetition remedies that protect, promote, and fulfill women's reproductive health rights. Litigation outcomes that determine there have been violations of reproductive rights are regarded as a "win" for health rights litigation, but when implementation fails, is a "win" still a win? There has been considerable success in litigating reproductive health rights cases, yet the Inter-American Commission on Human Rights and the Inter-American Court of Human Rights are not adequately equipped to follow up on cases after they have been won. Successful and sustainable implementation of reproductive health rights law requires incorporation of non-repetition remedies in the form of legislation, education, and training that seeks to remodel existing social and cultural practices that hinder women's enjoyment of their reproductive rights. In order for a reproductive health rights case to ultimately be a "winner," case recommendations and decisions emerging from the Commission and Court must incorporate perspectives from members of civil society, with the ultimate goal being to develop measurable remedies that address underlying obstacles to domestic implementation.

  1. Large rock-slope failures impacting on lakes - Reconstruction of events and deciphering mobility processes at Lake Oeschinen (CH) and Lake Eibsee (D)

    Science.gov (United States)

    Knapp, Sibylle; Anselmetti, Flavio; Gilli, Adrian; Krautblatter, Michael; Hajdas, Irka

    2017-04-01

    Among single event landslide disasters large rock-slope failures account for 75% of disasters with more than 1000 casualties. The precise determination of recurrence rates and failure volumes combined with an improved understanding of mobility processes are essential to better constrain runout models and establish early warning systems. Here we present the data sets from the two alpine regions Lake Oeschinen (CH) and Lake Eibsee (D) to show how lake studies can help to decipher the multistage character of rock-slope failures and to improve the understanding of the processes related to rock avalanche runout dynamics. We focus on such that impacted on a (paleo-) lake for two main reasons. First, the lake background sedimentation acts as a natural chronometer, which enables the stratigraphic positioning of events and helps to reconstruct the event history. This way it becomes possible to (i) decipher the multistage character of the failure of a certain rock slope and maybe detect progressive failure, (ii) determine the recurrence rates of failures at that certain rock slope, and (iii) consider energies based on estimated failure volumes, fall heights and deposition patterns. Hence, the interactions between a rock-slope failure, the water reservoir and the altered rock-slope are better understood. Second, picturing a rock avalanche running through and beyond a lake, we assume the entrainment of water and slurry to be crucial for the subsequent flow dynamics. The entrainment consumes a large share of the total energy, and orchestrates the mobility leading to fluidization, a much higher flow velocity and a longer runout-path length than expected. At Lake Oeschinen (CH) we used lake sediment cores and reflection seismic profiles in order to reconstruct the 2.5 kyrs spanning rock-slope failure history including 10 events, six of which detached from the same mountain flank, and correlated them with (pre-) historical data. The Lake Eibsee records provide insights into the

  2. A combined field and numerical approach to understanding dilute pyroclastic density current dynamics and hazard potential: Auckland Volcanic Field, New Zealand

    Science.gov (United States)

    Brand, Brittany D.; Gravley, Darren M.; Clarke, Amanda B.; Lindsay, Jan M.; Bloomberg, Simon H.; Agustin-Flores, Javier; Németh, Károly

    2014-04-01

    The most dangerous and deadly hazards associated with phreatomagmatic eruptions in the Auckland Volcanic Field (AVF; Auckland, New Zealand) are those related to volcanic base surges - dilute, ground-hugging, particle laden currents with dynamic pressures capable of severe to complete structural damage. We use the well-exposed base surge deposits of the Maungataketake tuff ring (Manukau coast, Auckland), to reconstruct flow dynamics and destructive potential of base surges produced during the eruption. The initial base surge(s) snapped trees up to 0.5 m in diameter near their base as far as 0.7-0.9 km from the vent. Beyond this distance the trees were encapsulated and buried by the surge in growth position. Using the tree diameter and yield strength of the wood we calculate that dynamic pressures (Pdyn) in excess of 12-35 kPa are necessary to cause the observed damage. Next we develop a quantitative model for flow of and sedimentation from a radially-spreading, dilute pyroclastic density currents (PDCs) to determine the damage potential of the base surges produced during the early phases of the eruption and explore the implications of this potential on future eruptions in the region. We find that initial conditions with velocities on the order of 65 m s- 1, bulk density of 38 kg m- 3 and initial, near-vent current thicknesses of 60 m reproduce the field-based Pdyn estimates and runout distances. A sensitivity analysis revealed that lower initial bulk densities result in shorter run-out distances, more rapid deceleration of the current and lower dynamic pressures. Initial velocity does not have a strong influence on run-out distance, although higher initial velocity and slope slightly decrease runout distance due to higher rates of atmospheric entrainment. Using this model we determine that for base surges with runout distances of up to 4 km, complete destruction can be expected within 0.5 km from the vent, moderate destruction can be expected up to 2 km, but much

  3. Determination of snow avalanche return periods using a tree-ring based reconstruction in the French Alps: cross validation with the predictions of a statistical-dynamical model

    Science.gov (United States)

    Schläppy, Romain; Eckert, Nicolas; Jomelli, Vincent; Grancher, Delphine; Brunstein, Daniel; Stoffel, Markus; Naaim, Mohamed

    2013-04-01

    Documenting past avalanche activity represents an indispensable step in avalanche hazard assessment. Nevertheless, (i) archival records of past avalanche events do not normally yield data with satisfying spatial and temporal resolution and (ii) precision concerning runout distance is generally poorly defined. In addition, historic documentation is most often (iii) biased toward events that caused damage to structure or loss of life on the one hand and (iv) undersampled in unpopulated areas on the other hand. On forested paths dendrogeomorphology has been demonstrated to represent a powerful tool to reconstruct past activity of avalanches with annual resolution and for periods covering the past decades to centuries. This method is based on the fact that living trees may be affected by snow avalanches during their flow and deposition phases. Affected trees will react upon these disturbances with a certain growth response. An analysis of the responses recorded in tree rings coupled with an evaluation of the position of reacting trees within the path allows the dendrogeomorphic expert to identify past snow avalanche events and deduced their minimum runout distance. The objective of the work presented here is firstly to dendrochronogically -reconstruct snow avalanche activity in the Château Jouan path located near Montgenèvre in the French Alps. Minimal runout distances are then determined for each reconstructed event by considering the point of further reach along the topographic profile. Related empirical return intervals are evaluated, combining the extent of each event with the average local frequency of the dendrological record. In a second step, the runout distance distribution derived from dendrochronological reconstruction is compared to the one derived from historical archives and to high return period avalanches predicted by an up-to-date locally calibrated statistical-numerical model. It appears that dendrochronological reconstructions correspond mostly to

  4. Granular Flow Dynamics on Earth, Moon, and Mars from analytical, numerical and field analysis

    Science.gov (United States)

    Lucas, A.; Mangeney, A.; Mhge, D.

    2010-12-01

    Prediction of landslides dynamics remains difficult in spite of a considerable body of work. A number of previous studies have been based on runout analysis in relation to mean dissipation calibration via the friction coefficient. However, the shape of the initial scar is generally unknown in real cases, which weakens landslide material spreading predictions and has alters calibration parameters of numerical models. We study numerically the effects of scar geometry on flow and distribution of the deposits and show that the initial shape of the scar, independent of the friction coefficient, does not affect the runout distance. In contrast, 3D tests show that the shape of the final deposits is a function of the scar geometry, and hence information on initial scar geometry and initial volume involved in the mass spreading may be retrieved from analysis of final deposit morphology. From an analytical solution we show here why the classical mobility (defined as the ratio between total height and runout distance) decreases when the volume increases, as is generally observed in geological data. We thus introduce analytically a new mobility variable obtained from geomorphic measurements reflecting the intrinsic dissipation independent of the aspect ratio, of the volume of the granular mass involved, of the underlying topography, and of the initial scar geometry. Comparison between experimental results, terrestrial, Lunar and Martian cases highlights a larger new mobility measure of natural granular flows compared to dry mass spreading simulated in the laboratory. In addition, landslides in a similar geological context give a single value showing the robustness of this new parameter. Finally, the new mobility provides a first order estimate of the effective friction required in models to reproduce the extent of the deposits in a given geological context. This enables a feedback analysis method for retrieving the volume and shape of the initial landslide material and then

  5. Simulations of Debris-Flow Dominated Margins with Relevance to Morphologic Evolution of Trough-Mouth Fans

    Science.gov (United States)

    O'Grady, D. B.; Syvitski, J. P.

    2001-12-01

    Large-scale morphology of glacier-fed continental slopes is influenced by the rate and method of sediment delivery to the slope through time. Slopes fed by fast flowing ice streams (i.e. at trough-mouth fans) and dominated by debris flow deposition exhibit a morphology that is inherently different from other types of glacial margins. Empirical analyses suggest that the average gradient of a trough mouth fan is related to the width of the adjacent continental shelf and, correlatively, to the amount of sediment delivered to the margin by the ice stream. This gradient relationship is not observed for other polar margins. A process-based stratigraphic model (SedFlux) is used to examine the evolution of debris-flow dominated continental slopes under differing boundary conditions and flow properties. Margins are simulated as building from initial bathymetry of a simple shelf-slope-rise configuration. The angle of the continental slope varies between simulations ranging from 1 to 10 degrees. In addition to boundary conditions, the kinematic viscosity (0.0001 m2/s to 0.1 m2/s) and yield strength (1 pa to 500 pa) of the debris flows varies between model runs. The changing morphology of the margin is tracked by measuring the gradient of the margin profile throughout the simulation. Also tracked are the runout distances of the flows and their deposit thickness. Hydroplaning debris flows are not explicitly modeled but are approximated by implementing very low viscosities. Results show that basin depth influences the runout length of debris flows and subsequently the length of the margin slope. The rate of sediment input influences the number and frequency of slope failures leading to debris flows although the overall morphology does not change in response to sediment input rate. All simulations show an evolution of profile morphology as the margin progrades outward, with the continental slope becoming less steep through time. This morphologic evolution is coupled with a

  6. Two early Holocene rock avalanches in the Bernese Alps (Rinderhorn, Switzerland)

    Science.gov (United States)

    Grämiger, Lorenz M.; Moore, Jeffrey R.; Vockenhuber, Christof; Aaron, Jordan; Hajdas, Irka; Ivy-Ochs, Susan

    2016-09-01

    Large rock avalanches constitute a critical process modulating the evolution of alpine landscapes; however, the relatively infrequent occurrence of these high-magnitude events makes identifying underlying process controls challenging. Here we describe two rock avalanches in the Rinderhorn area of the Bernese Alps, Switzerland, providing new mapping of rock avalanche source areas and deposits, refined volume estimates for each event, runout modeling back-analyses, and absolute age constraint from cosmogenic 36Cl surface exposure dating. Results reveal that the Daubensee rock avalanche released ~ 4 million m3 of limestone sliding from the western crest of the Rinderhorn. Debris ran out across a Lateglacial moraine before reaching the valley bottom and spreading, leaving thin (on average 7 m) deposits across a broad area. The runout resulted in a Fahrböschung angle of 21°. Part of the deposit now lies beneath Lake Daubensee. The Klein Rinderhorn rock avalanche released ~ 37 million m3 of limestone along a dip-slope sliding plane, with a maximum runout distance of 4.3 km and estimated Fahrböschung angle of 14°. Deposits bulked to ~ 47 million m3 running up the opposing slope, with distinct hummocky morphology in the proximal area and a distal longitudinal flow ridge. These deposits were later modified and partly obscured by ice avalanches from the nearby Altels peak. Cosmogenic 36Cl surface exposure dating revealed nearly coincident ages for both rock avalanches of 9.8 ± 0.5 ka. The large lag time between local deglaciation and failure suggests that the events were not directly triggered by deglaciation. Rather, the concurrent exposure ages, also coinciding with the nearby Kander valley rock avalanche as well as paleoseismic records from nearby lakes, strongly suggest seismic triggering.

  7. Modeling granular material flows: The angle of repose, fluidization and the cliff collapse problem

    Science.gov (United States)

    Holsapple, Keith A.

    2013-07-01

    I discuss theories of granular material flows, with application to granular flows on the earth and planets. There are two goals. First, there is a lingering belief of some that the standard continuum plasticity Mohr-Coulomb and/or Drucker-Prager models are not adequate for many large-scale granular flow problems. The stated reason for those beliefs is the fact that the final slopes of the run-outs in collapse, landslide problems, and large-scale cratering are well below the angle of repose of the material. That observation, combined with the supposition that in those models flow cannot occur with slopes less than the angle of repose, has led to a number of researchers suggesting a need for lubrication or fluidization mechanisms and modeling. That issue is investigated in detail and shown to be false. A complete analysis of slope failures according to the Mohr-Coulomb model is presented, with special attention to the relations between the angle of repose and slope failures. It is shown that slope failure can occur for slope angles both larger than and smaller than the angle of repose. Second, to study the details of landslide run-outs, finite-difference continuum code simulations of the prototypical cliff collapse problem, using the classical plasticity models, are presented, analyzed and compared to experiments. Although devoid of any additional fluidization models, those simulations match experiments in the literature extremely well. The dynamics of this problem introduces additional important features relating to the run-out and final slope angles. The vertical free surface begins to fall at the initial 90° and flow continues to a final slope less than 10°. The detail in the calculation is examined to show why flow persists at slope angles that appear to be less than the angle of repose. The motions include regions of solid-like, fluid-like, and gas-like flows without invoking any additional models.

  8. Impact of the 2008 Wenchuan earthquake in China on subsequent long-term debris flow activities in the epicentral area

    Science.gov (United States)

    Zhang, S.; Zhang, L. M.

    2017-01-01

    The 2008 Wenchuan earthquake triggered the largest number of landslides among the recent strong earthquake events around the world. The loose landslide materials were retained on steep terrains and deep gullies. In the period from 2008 to 2015, numerous debris flows occurred during rainstorms along the Provincial Road 303 (PR303) near the epicentre of the earthquake, causing serious damage to the reconstructed highway. Approximately 5.24 × 106 m3 of debris-flow sediment was deposited shortly after the earthquake. This paper evaluates the evolution of the debris flows that occurred after the Wenchuan earthquake, which helps understand long-term landscape evolution and cascading effects in regions impacted by mega earthquakes. With the aid of a GIS platform combined with field investigations, we continuously tracked movements of the loose deposit materials in all the debris flow gullies along an 18 km reach of PR303 and the characteristics of the regional debris flows during several storms in the past seven years. This paper presents five important aspects of the evolution of debris flows: (1) supply of debris flow materials; (2) triggering rainfall; (3) initiation mechanisms and types of debris flows; (4) runout characteristics; and (5) elevated riverbed due to the deposited materials from the debris flows. The hillslope soil deposits gradually evolved into channel deposits and the solid materials in the channels moved towards the ravine mouth. Accordingly, channelized debris flows became dominant gradually. Due to the decreasing source material volume and changes in debris flow characteristics, the triggering rainfall tends to increase from 30 mm h- 1 in 2008 to 64 mm h- 1 in 2013, and the runout distance tends to decrease over time. The runout materials blocked the river and elevated the riverbed by at least 30 m in parts of the study area. The changes in the post-seismic debris flow activity can be categorized into three stages, i.e., active, unstable, and

  9. Validation of TITAN2D flow model code for pyroclastic flows and debris avalanches at Soufrière Hills Volcano, Montserrat, BWI

    Science.gov (United States)

    Widiwijayanti, C.; Voight, B.; Hidayat, D.; Patra, A.; Pitman, E.

    2004-12-01

    Soufrière Hills Volcano (SHV), Montserrat, has experienced numerous episodes of dome collapses since 1996. They range from relatively small rockfalls to major dome collapses, several >10x106 m3, and one >100x106 m3 (Calder, Luckett, Sparks and Voight 2002; Voight et al. 2002). The hazard implications for such events are significant at both local and regional scales, and include pyroclastic surges, explosions, and tsunami. Problems arise in forecasting and hazards mitigation, particularly in zoning for populated areas. Determining the likely extent of flow deposits is important for hazard zonation. For this, detailed mapping (topography of source areas and paths, material properties, structure, track roughness and erosion) has an important role, giving clues on locations of future collapse and runout paths. Here we present an application of a numerical computation model of geophysical mass flow using the TITAN2D code (Patra et al. 2004; Pitman et al. 2004), to simulate dome collapses at SHV. The majority of collapse-type pyroclastic flows at SHV are consistent with an initiation by gravitational collapse of oversteepened flanks of the dome. If the gravity controls the energy for such processes, then the flow tracks can be predicted on the basis of topography, and friction influences runout. TITAN2D is written to simulate this type of volcanic flow, and the SHV database is used to validate the code and provide calibrated data on friction properties. The topographic DEM was successively updated by adding flow deposit thicknesses for previous collapses. Simulation results were compared to observed flow parameters, including flow path, deposit volume, duration, velocity, and runout distance of individual flows, providing calibration data on internal and bed friction, and demonstrating the validity and limitations of such modeling for practical volcanic hazard assessment.

  10. Observations of debris flows at Chalk Cliffs, Colorado, USA: Part 1, in-situ measurements of flow dynamics, tracer particle movement and video imagery from the summer of 2009

    Science.gov (United States)

    McCoy, Scott W.; Coe, Jeffrey A.; Kean, Jason W.; Tucker, Greg E.; Staley, Dennis M.; Wasklewicz, Thad A.

    2011-01-01

    Debris flows initiated by surface-water runoff during short duration, moderate- to high-intensity rainfall are common in steep, rocky, and sparsely vegetated terrain. Yet large uncertainties remain about the potential for a flow to grow through entrainment of loose debris, which make formulation of accurate mechanical models of debris-flow routing difficult. Using a combination of in situ measurements of debris flow dynamics, video imagery, tracer rocks implanted with passive integrated transponders (PIT) and pre- and post-flow 2-cm resolution digital terrain models (terrain data presented in a companion paper by STALEY et alii, 2011), we investigated the entrainment and transport response of debris flows at Chalk Cliffs, CO, USA. Four monitored events during the summer of 2009 all initiated from surface-water runoff, generally less than an hour after the first measurable rain. Despite reach-scale morphology that remained relatively constant, the four flow events displayed a range of responses, from long-runout flows that entrained significant amounts of channel sediment and dammed the main-stem river, to smaller, short-runout flows that were primarily depositional in the upper basin. Tracer-rock travel-distance distributions for these events were bimodal; particles either remained immobile or they travelled the entire length of the catchment. The long-runout, large-entrainment flow differed from the other smaller flows by the following controlling factors: peak 10-minute rain intensity; duration of significant flow in the channel; and to a lesser extent, peak surge depth and velocity. Our growing database of natural debris-flow events can be used to develop linkages between observed debris-flow transport and entrainment responses and the controlling rainstorm characteristics and flow properties.

  11. EDDA 1.0: integrated simulation of debris flow erosion, deposition and property changes

    Science.gov (United States)

    Chen, H. X.; Zhang, L. M.

    2015-03-01

    Debris flow material properties change during the initiation, transportation and deposition processes, which influences the runout characteristics of the debris flow. A quasi-three-dimensional depth-integrated numerical model, EDDA (Erosion-Deposition Debris flow Analysis), is presented in this paper to simulate debris flow erosion, deposition and induced material property changes. The model considers changes in debris flow density, yield stress and dynamic viscosity during the flow process. The yield stress of the debris flow mixture determined at limit equilibrium using the Mohr-Coulomb equation is applicable to clear water flow, hyper-concentrated flow and fully developed debris flow. To assure numerical stability and computational efficiency at the same time, an adaptive time stepping algorithm is developed to solve the governing differential equations. Four numerical tests are conducted to validate the model. The first two tests involve a one-dimensional debris flow with constant properties and a two-dimensional dam-break water flow. The last two tests involve erosion and deposition, and the movement of multi-directional debris flows. The changes in debris flow mass and properties due to either erosion or deposition are shown to affect the runout characteristics significantly. The model is also applied to simulate a large-scale debris flow in Xiaojiagou Ravine to test the performance of the model in catchment-scale simulations. The results suggest that the model estimates well the volume, inundated area, and runout distance of the debris flow. The model is intended for use as a module in a real-time debris flow warning system.

  12. EDDA: integrated simulation of debris flow erosion, deposition and property changes

    Directory of Open Access Journals (Sweden)

    H. X. Chen

    2014-11-01

    Full Text Available Debris flow material properties change during the initiation, transportation and deposition processes, which influences the runout characteristics of the debris flow. A quasi-three-dimensional depth-integrated numerical model, EDDA, is presented in this paper to simulate debris flow erosion, deposition and induced material property changes. The model considers changes in debris flow density, yield stress and dynamic viscosity during the flow process. The yield stress of debris flow mixture is determined at limit equilibrium using the Mohr–Coulomb equation, which is applicable to clear water flow, hyper-concentrated flow and fully developed debris flow. To assure numerical stability and computational efficiency at the same time, a variable time stepping algorithm is developed to solve the governing differential equations. Four numerical tests are conducted to validate the model. The first two tests involve a one-dimensional dam-break water flow and a one-dimensional debris flow with constant properties. The last two tests involve erosion and deposition, and the movement of multi-directional debris flows. The changes in debris flow mass and properties due to either erosion or deposition are shown to affect the runout characteristics significantly. The model is also applied to simulate a large-scale debris flow in Xiaojiagou Ravine to test the performance of the model in catchment-scale simulations. The results suggest that the model estimates well the volume, inundated area, and runout distance of the debris flow. The model is intended for use as a module in a real-time debris flow warning system.

  13. EDDA: integrated simulation of debris flow erosion, deposition and property changes

    Science.gov (United States)

    Chen, H. X.; Zhang, L. M.

    2014-11-01

    Debris flow material properties change during the initiation, transportation and deposition processes, which influences the runout characteristics of the debris flow. A quasi-three-dimensional depth-integrated numerical model, EDDA, is presented in this paper to simulate debris flow erosion, deposition and induced material property changes. The model considers changes in debris flow density, yield stress and dynamic viscosity during the flow process. The yield stress of debris flow mixture is determined at limit equilibrium using the Mohr-Coulomb equation, which is applicable to clear water flow, hyper-concentrated flow and fully developed debris flow. To assure numerical stability and computational efficiency at the same time, a variable time stepping algorithm is developed to solve the governing differential equations. Four numerical tests are conducted to validate the model. The first two tests involve a one-dimensional dam-break water flow and a one-dimensional debris flow with constant properties. The last two tests involve erosion and deposition, and the movement of multi-directional debris flows. The changes in debris flow mass and properties due to either erosion or deposition are shown to affect the runout characteristics significantly. The model is also applied to simulate a large-scale debris flow in Xiaojiagou Ravine to test the performance of the model in catchment-scale simulations. The results suggest that the model estimates well the volume, inundated area, and runout distance of the debris flow. The model is intended for use as a module in a real-time debris flow warning system.

  14. Recombinant Dragline Silk-Like Proteins—Expression and Purification

    Science.gov (United States)

    Gaines, William A.; Marcotte, William R.

    2011-01-01

    Spider dragline silk is a proteinaceous fiber with impressive physical characteristics making it attractive for use in advanced materials. The fiber is composed of two proteins (spidroins MaSp1 and MaSp2), each of which contains a large central repeat array flanked by non-repetitive N- and C-terminal domains. The repeat arrays appear to be largely responsible for the tensile properties of the fiber, suggesting that the N- and C-terminal domains may be involved in self-assembly. We recently isolated the MaSp1 and MaSp2 N-terminal domains from Nephila clavipes and have incorporated these into mini-silk genes for expression in transgenic systems. Current efforts involve the development of expression vectors that will allow purification using a removable affinity tag for scalable protein purification. PMID:23914141

  15. Recombinant Dragline Silk-Like Proteins-Expression and Purification.

    Science.gov (United States)

    Gaines, William A; Marcotte, William R

    2011-03-01

    Spider dragline silk is a proteinaceous fiber with impressive physical characteristics making it attractive for use in advanced materials. The fiber is composed of two proteins (spidroins MaSp1 and MaSp2), each of which contains a large central repeat array flanked by non-repetitive N- and C-terminal domains. The repeat arrays appear to be largely responsible for the tensile properties of the fiber, suggesting that the N- and C-terminal domains may be involved in self-assembly. We recently isolated the MaSp1 and MaSp2 N-terminal domains from Nephila clavipes and have incorporated these into mini-silk genes for expression in transgenic systems. Current efforts involve the development of expression vectors that will allow purification using a removable affinity tag for scalable protein purification.

  16. Analysis of ultrasonic techniques for monitoring milk coagulation during cheesemaking

    Science.gov (United States)

    Budelli, E.; Pérez, N.; Lema, P.; Negreira, C.

    2012-12-01

    Experimental determination of time of flight and attenuation has been proposed in the literature as alternatives to monitoring the evolution of milk coagulation during cheese manufacturing. However, only laboratory scale procedures have been described. In this work, the use of ultrasonic time of flight and attenuation to determine cutting time and its feasibility to be applied at industrial scale were analyzed. Limitations to implement these techniques at industrial scale are shown experimentally. The main limitation of the use of time of flight is its strong dependence with temperature. Attenuation monitoring is affected by a thin layer of milk skin covering the transducer, which modifies the signal in a non-repetitive way. The results of this work can be used to develop alternative ultrasonic systems suitable for application in the dairy industry.

  17. Repetitive motion planning and control of redundant robot manipulators

    CERN Document Server

    Zhang, Yunong

    2013-01-01

    Repetitive Motion Planning and Control of Redundant Robot Manipulators presents four typical motion planning schemes based on optimization techniques, including the fundamental RMP scheme and its extensions. These schemes are unified as quadratic programs (QPs), which are solved by neural networks or numerical algorithms. The RMP schemes are demonstrated effectively by the simulation results based on various robotic models; the experiments applying the fundamental RMP scheme to a physical robot manipulator are also presented. As the schemes and the corresponding solvers presented in the book have solved the non-repetitive motion problems existing in redundant robot manipulators, it is of particular use in applying theoretical research based on the quadratic program for redundant robot manipulators in industrial situations. This book will be a valuable reference work for engineers, researchers, advanced undergraduate and graduate students in robotics fields. Yunong Zhang is a professor at The School of Informa...

  18. Combination of ARDRA and RAPD genotyping techniques in identification of Acinetobacter spp. genomic species

    Institute of Scientific and Technical Information of China (English)

    Yong ZHANG; Yuqing CHEN; Yingchun TANG; Kouxing ZHANG

    2008-01-01

    A total of 10 non-repetitive multi-drug-resist-ant Acinetobacter strains were collected. With reference to A. calcoaceticus (ATCC23055), A. baumannii (ATCC19606), A. lwoffii (ATCC17986), and A. junii (NCTC5866), DNA fingerprint technique, amplified ribo-somal DNA restriction analysis (ARDRA), and random amplified polymorphism DNA (RAPD) were carried out to identify the genomic species of Acinetobacter spp. The distances between them were calculated by the unweighted pair group method with arithmetic (UPGMA). Genotypes ofAcinetobacter spp. were effectively classified and an A. junii together with nine A. baumannii isolates was genomically identified. The combination of ARDRA and RAPD DNA-fingerprint technique shows high com-plementarity, and could be a useful tool in Acinetobacter genomic species identification.

  19. High-order harmonics with frequency-varying polarization within each harmonic

    CERN Document Server

    Fleischer, Avner; Sidorenko, Pavel; Cohen, Oren

    2014-01-01

    We predict high-order harmonics in which the polarization within the spectral bandwidth of each harmonic varies continuously and significantly. For example, the interaction of counter-rotating circularly-polarized bichromatic drivers having close central frequencies with isotropic gas leads to the emission of polarization-fan harmonics which are nearly circularly-polarized in one tail of the harmonic peak, linear in the center of the peak and nearly circular with the opposite helicity in the opposite tail. Polarization fan harmonics are obtained as a result of multiple (at least two) head-on recollisions of electrons with their parent ions occurring from different angles. The process can be phase-matched using standard methods (e.g. pressure tuning phase matching) and maintains the single-atom polarization property through propagation. These polarization-fan harmonics may be used for exploring non-repetitive ultrafast chiral phenomena, e.g. dynamics of magnetic domains, in a single shot

  20. Evolutionarily conserved sequences on human chromosome 21

    Energy Technology Data Exchange (ETDEWEB)

    Frazer, Kelly A.; Sheehan, John B.; Stokowski, Renee P.; Chen, Xiyin; Hosseini, Roya; Cheng, Jan-Fang; Fodor, Stephen P.A.; Cox, David R.; Patil, Nila

    2001-09-01

    Comparison of human sequences with the DNA of other mammals is an excellent means of identifying functional elements in the human genome. Here we describe the utility of high-density oligonucleotide arrays as a rapid approach for comparing human sequences with the DNA of multiple species whose sequences are not presently available. High-density arrays representing approximately 22.5 Mb of nonrepetitive human chromosome 21 sequence were synthesized and then hybridized with mouse and dog DNA to identify sequences conserved between humans and mice (human-mouse elements) and between humans and dogs (human-dog elements). Our data show that sequence comparison of multiple species provides a powerful empiric method for identifying actively conserved elements in the human genome. A large fraction of these evolutionarily conserved elements are present in regions on chromosome 21 that do not encode known genes.

  1. Decorative design of ceramic tiles adapted to inkjet printing employing digital image processing; Diseno decorativo de pavimentos ceramicos adaptado a inyeccion de tinta mediante tratamiento digital de imagen

    Energy Technology Data Exchange (ETDEWEB)

    Defez, B.; Santiago-Praderas, V.; Lluna, E.; Peris-Fajarnes, G.; Dunai, E.

    2013-09-01

    The ceramic tile sector is a very competitive industry. The designer's proficiency to offer new models of the decorated surface, adapted to the production means, plays a very important role in the competitiveness. In the present work, we analyze the evolution of the design process in the ceramic sector, as much as the changes experimented in parallel by the printing equipment. Afterwards, we present a new concept of ceramic design, based on digital image processing. This technique allows the generation of homogeneous and non-repetitive designs for large surfaces, especially thought for inkjet printing. With the programmed algorithms we have compiled a prototype software for the assistance of the ceramic design. This tool allows creating continuous designs for large surfaces saving developing time. (Author)

  2. Toward spinning artificial spider silk.

    Science.gov (United States)

    Rising, Anna; Johansson, Jan

    2015-05-01

    Spider silk is strong and extensible but still biodegradable and well tolerated when implanted, making it the ultimate biomaterial. Shortcomings that arise in replicating spider silk are due to the use of recombinant spider silk proteins (spidroins) that lack native domains, the use of denaturing conditions under purification and spinning and the fact that the understanding of how spiders control silk formation is incomplete. Recent progress has unraveled the molecular mechanisms of the spidroin N- and C-terminal nonrepetitive domains (NTs and CTs) and revealed the pH and ion gradients in spiders' silk glands, clarifying how spidroin solubility is maintained and how silk is formed in a fraction of a second. Protons and CO2, generated by carbonic anhydrase, affect the stability and structures of the NT and CT in different ways. These insights should allow the design of conditions and devices for the spinning of recombinant spidroins into native-like silk.

  3. Structural characterization of the major ampullate silk spidroin-2 protein produced by the spider Nephila clavipes.

    Science.gov (United States)

    Santos-Pinto, José Roberto Aparecido Dos; Arcuri, Helen Andrade; Lubec, Gert; Palma, Mario Sergio

    2016-10-01

    Major ampullate spidroin-2 (MaSp2) is one of the most important spider silk protein, but up to now no information is available regarding the post-translational modifications (PTMs) of this protein. A gel-based mass spectrometry strategy using collision-induced dissociation (CID) and electron-transfer dissociation (ETD) fragmentation methods was used to sequence Nephila clavipes MaSp2 (including the N- and C-terminal non-repetitive domains, and the great part of the central core), and to assign a series of post-translational modifications (PTMs) on to the MaSp2 sequence. Two forms of this protein were identified, with different levels of phosphorylation along their sequences. These findings provide a basis for understanding mechanoelastic properties and can support the future design of recombinant spider silk proteins for biotechnological applications. Copyright © 2016 Elsevier B.V. All rights reserved.

  4. Using Repeating Decimals As An Alternative To Prime Numbers In Encryption

    CERN Document Server

    Zirkind, Givon

    2010-01-01

    This article is meant to provide an additional point of view, applying known knowledge, to supply keys that have a series of non-repeating digits, in a manner that is not usually thought of. Traditionally, prime numbers are used in encryption as keys that have non-repeating sequences. Usually, non-repetition, especially of digits in a key, is very sought after in encryption. Uniqueness in a digit sequence defeats decryption. In searching for methods of non-decryptable encryption as well as ways to provide unique sequences, other than using prime numbers [5], the idea of using repeating decimals came to me. Applied correctly, a repeating decimal series of sufficient length will stand in as well for a prime number. This is so, because only numbers prime to each other will produce repeating decimals and; within the repeating sequence there is uniqueness of digit sequence.

  5. Using Repeating Decimals As An Alternative To Prime Numbers In Encryption

    CERN Document Server

    Zirkind, Givon

    2010-01-01

    This article is meant to provide an additional point of view, applying known knowledge, to supply keys that have a series of non-repeating digits, in a manner that is not usually thought of. Traditionally, prime numbers are used in encryption as keys that have non-repeating sequences. Non-repetition of digits in a key is very sought after in encryption. Uniqueness in a digit sequence defeats decryption by method. In searching for methods of non-decryptable encryption as well as ways to provide unique sequences, other than using prime numbers, the idea of using repeating decimals came to me. Applied correctly, a repeating decimal series of sufficient length will stand in as well for a prime number. This is so, because only numbers prime to each other will produce repeating decimals and; within the repeating sequence there is uniqueness of digit sequence.

  6. NEGATIVE AFFECTIVITY, CONSCIENTIOUSNESS AND JOB SCOPE (A CASE OF IT AND TELECOM INDUSTRY

    Directory of Open Access Journals (Sweden)

    BILAL AFSAR

    2010-01-01

    Full Text Available Based on a sample of 350 employees in the telecommunication and telecommunication, we obtained empirical evidence suggesting that while individuals high on conscientiousness tended to react more positively to job scope, individuals high on negative affinity tended to react less positively. Job scope was defined as the extent to which a job required the jobholder to be mentally and physically involved to get it done effectively. Typically, a job characterized by a high job scope would be non-repetitive, would need a great deal of independent thought/action and training, would entail the job holder to keep track of his/her progress, and others. The affirmative results obtained in regard of the moderating roles of personality factors in the present study suggested that job design researchers should further explore individuals’ personality differences in response to job scope.

  7. Pigs in sequence space: A 0.66X coverage pig genome survey based on shotgun sequencing

    DEFF Research Database (Denmark)

    Wernersson, Rasmus; Schierup, M.H.; Jorgensen, F.G.

    2005-01-01

    efficient in pig compared to human, but not as efficient as in mouse, and pig seems to have an isochore structure most similar to the structure in human. Conclusion: The addition of the pig to the set of species sequenced at low coverage adds to the understanding of selective pressures that have acted...... sequences (0.66X coverage) from the pig genome. The data are hereby released (NCBI Trace repository with center name "SDJVP", and project name "Sino-Danish Pig Genome Project") together with an initial evolutionary analysis. The non-repetitive fraction of the sequences was aligned to the UCSC human......-mouse alignment and the resulting three-species alignments were annotated using the human genome annotation. Ultra-conserved elements and miRNAs were identified. The results show that for each of these types of orthologous data, pig is much closer to human than mouse is. Purifying selection has been more...

  8. Actuación del representante judicial de víctimas en la versión libre dentro del proceso de justicia y paz

    Directory of Open Access Journals (Sweden)

    Alait Freja Calao

    2011-09-01

    Full Text Available The Act 975 of 2005 which establishes a process of transitional and restorative justice has as objectives first, to facilitate peace processes and second, to reintegrate into society, collective or individually, illegal armed group members. However, this process should grant victims’ rights to truth, justice and reparation, and non-repetition of abuses. Hence, the process highlights the victim as its main character and it conditions the criminals nominated to the benefits of the Justice and peace process, as with the alternative sentencing, in order to ensure the right to integral reparation of damages suffered as consequence of the grave human rights violations to which the victims were subject of. This article seeks to outline the legal representative’s role for victims to finally accomplish this within the framework of Justice and peace process

  9. Cross-resistance between trimethoprim-sulfamethoxazole and other common antibiotics among urinary isolates of escherichia coli - an in-vitro retrospective analysis

    Directory of Open Access Journals (Sweden)

    B V Navaneeth

    2001-01-01

    Full Text Available 472 non-repetitive urinary isolates of E.coli (349 resistant and 123 sensitive to trimethoprim-sulfametho.xazole from patients with culture documented UTI were isolated between January 1998-December 1999. Data on antibiograrn of these isolates were fed into WHONET computer program. The relationship between trimethoprim-sulfamethoxazole (T-S resistance and resistance to other common antimicrobials among E. coli was statistically analyzed by comparing T-S resistant with T-S sensitive isolates against other antimicrobial agents. T-S resistant E.coli were more likely to be resistant to ampicillin, augmentin, cejazolin and norfloxacin (P0.05. T-S resistance among urinary isolates of E.coli may be a risk fatctor that would likely be associated with resistance to other antimicrobial agents used to treat UTI.

  10. A lincRNA switch for embryonic stem cell fate

    Institute of Scientific and Technical Information of China (English)

    Liuqing Yang; Chunru Lin; Michael G Rosenfeld

    2011-01-01

    Cumulative evidences have demonstrated that most of the non-repetitive genome in higher organisms are actively transcribed and surprisingly only a small percentage (< 20%) of transcripts are associated with genes that encode proteins [1].One of the emerging themes in the study of non-coding transcripts is large intergenic non-coding RNAs (lincRNAs),a class of large regulatory RNAs implicated in imprinting,dosage compensation,and transcriptional regulation [2].In light of recent discoveries revealing the flexibility of lincRNAs and their abilities to act as modular scaffolds for protein-chromatin interactions and to form spatially compact arrays of complexes [3,4],many would acknowledge that most lincRNAs act as sensors and integrators of a wide variety of regulated transcriptional responses and probably epigenetic events,which may have an impact on various human diseases.

  11. NMR assignments of the N-terminal domain of Nephila clavipes spidroin 1.

    Science.gov (United States)

    Parnham, Stuart; Gaines, William A; Duggan, Brendan M; Marcotte, William R; Hennig, Mirko

    2011-10-01

    The building blocks of spider dragline silk are two fibrous proteins secreted from the major ampullate gland named spidroins 1 and 2 (MaSp1, MaSp2). These proteins consist of a large central domain composed of approximately 100 tandem copies of a 35-40 amino acid repeat sequence. Non-repetitive N and C-terminal domains, of which the C-terminal domain has been implicated to transition from soluble and insoluble states during spinning, flank the repetitive core. The N-terminal domain until recently has been largely unknown due to difficulties in cloning and expression. Here, we report nearly complete assignment for all (1)H, (13)C, and (15)N resonances in the 14 kDa N-terminal domain of major ampullate spidroin 1 (MaSp1-N) of the golden orb-web spider Nephila clavipes.

  12. A noncoding, regulatory mutation implicates HCFC1 in nonsyndromic intellectual disability.

    Science.gov (United States)

    Huang, Lingli; Jolly, Lachlan A; Willis-Owen, Saffron; Gardner, Alison; Kumar, Raman; Douglas, Evelyn; Shoubridge, Cheryl; Wieczorek, Dagmar; Tzschach, Andreas; Cohen, Monika; Hackett, Anna; Field, Michael; Froyen, Guy; Hu, Hao; Haas, Stefan A; Ropers, Hans-Hilger; Kalscheuer, Vera M; Corbett, Mark A; Gecz, Jozef

    2012-10-01

    The discovery of mutations causing human disease has so far been biased toward protein-coding regions. Having excluded all annotated coding regions, we performed targeted massively parallel resequencing of the nonrepetitive genomic linkage interval at Xq28 of family MRX3. We identified in the binding site of transcription factor YY1 a regulatory mutation that leads to overexpression of the chromatin-associated transcriptional regulator HCFC1. When tested on embryonic murine neural stem cells and embryonic hippocampal neurons, HCFC1 overexpression led to a significant increase of the production of astrocytes and a considerable reduction in neurite growth. Two other nonsynonymous, potentially deleterious changes have been identified by X-exome sequencing in individuals with intellectual disability, implicating HCFC1 in normal brain function.

  13. Musculoskeletal disorders of the neck and shoulders in female sewing machine operators: prevalence, incidence, and prognosis

    DEFF Research Database (Denmark)

    Kaergaard, A.; Andersen, JH

    2000-01-01

    for two main neck-shoulder disorders were defined: rotator cuff tendinitis and myofascial pain syndrome. A baseline control group consisted of 357 women with varied non-repetitive work. RESULTS: At baseline the overall prevalence of myofascial pain syndrome and rotator cuff tendinitis was 15.2% and 5...... ratio (PR)=2.54; 95% confidence interval (95% CI) 1.28 to 5.05) when adjusted for age, body mass index, smoking, living alone with children, job strain, and social support from colleagues and supervisors. Only one of 13 participants with rotator cuff tendinitis at baseline recovered during follow up...... with children. CONCLUSION: Rotator cuff tendinitis showed a higher degree of persistence than myofascial pain syndrome. Both disorders highly influenced the perception of general health. Women who lived alone with children, were smokers, or experienced low support from colleagues and supervisors had a higher...

  14. Widefield laser doppler velocimeter: development and theory.

    Energy Technology Data Exchange (ETDEWEB)

    Hansche, Bruce David; Reu, Phillip L.; Massad, Jordan Elias

    2007-03-01

    The widefield laser Doppler velocimeter is a new measurement technique that significantly expands the functionality of a traditional scanning system. This new technique allows full-field velocity measurements without scanning, a drawback of traditional measurement techniques. This is particularly important for tests in which the sample is destroyed or the motion of the sample is non-repetitive. The goal of creating ''velocity movies'' was accomplished during the research, and this report describes the current functionality and operation of the system. The mathematical underpinnings and system setup are thoroughly described. Two prototype experiments are then presented to show the practical use of the current system. Details of the corresponding hardware used to collect the data and the associated software to analyze the data are presented.

  15. VideoWeb Dataset for Multi-camera Activities and Non-verbal Communication

    Science.gov (United States)

    Denina, Giovanni; Bhanu, Bir; Nguyen, Hoang Thanh; Ding, Chong; Kamal, Ahmed; Ravishankar, Chinya; Roy-Chowdhury, Amit; Ivers, Allen; Varda, Brenda

    Human-activity recognition is one of the most challenging problems in computer vision. Researchers from around the world have tried to solve this problem and have come a long way in recognizing simple motions and atomic activities. As the computer vision community heads toward fully recognizing human activities, a challenging and labeled dataset is needed. To respond to that need, we collected a dataset of realistic scenarios in a multi-camera network environment (VideoWeb) involving multiple persons performing dozens of different repetitive and non-repetitive activities. This chapter describes the details of the dataset. We believe that this VideoWeb Activities dataset is unique and it is one of the most challenging datasets available today. The dataset is publicly available online at http://vwdata.ee.ucr.edu/ along with the data annotation.

  16. Prenatal Genetic Diagnosis in 481 Amniocentesis, Chorion Villi Sample and Cordocentesis Specimens

    Directory of Open Access Journals (Sweden)

    Turgay Budak

    2007-01-01

    Full Text Available In this study, we evaluated a total of 481 amniocentesis , cordocentesis and corion villi sample specimens from patients who were referred to the Prenatal Diagnostic Laboratory of Department of Medical Biology and Genetics Department of Medical Faculty of University of Dicle, between 1999 and 2001. A total of 24 specimens were found cytogenetically abnormal, of which 11 were trisomy 21 ( Down Syndrome, two were Down Syndrome with Robertsonian type of translocation between chromosome 14 and 21, one was mosaic Down Syndrome , one was balanced translocated chromosome carrier, two were Turner Syndrome, one was triple X syndrome, two were triploidy, one was partial trisomy 3, one was derivative chromosome, one was nonrepetitive numerical and structural abnormality, and one was marker chromosome. Unfortunately, we could not have results in 15 of culture samples. There were no false positive and false negative results.

  17. Atrx promotes heterochromatin formation at retrotransposons.

    Science.gov (United States)

    Sadic, Dennis; Schmidt, Katharina; Groh, Sophia; Kondofersky, Ivan; Ellwart, Joachim; Fuchs, Christiane; Theis, Fabian J; Schotta, Gunnar

    2015-07-01

    More than 50% of mammalian genomes consist of retrotransposon sequences. Silencing of retrotransposons by heterochromatin is essential to ensure genomic stability and transcriptional integrity. Here, we identified a short sequence element in intracisternal A particle (IAP) retrotransposons that is sufficient to trigger heterochromatin formation. We used this sequence in a genome-wide shRNA screen and identified the chromatin remodeler Atrx as a novel regulator of IAP silencing. Atrx binds to IAP elements and is necessary for efficient heterochromatin formation. In addition, Atrx facilitates a robust and largely inaccessible heterochromatin structure as Atrx knockout cells display increased chromatin accessibility at retrotransposons and non-repetitive heterochromatic loci. In summary, we demonstrate a direct role of Atrx in the establishment and robust maintenance of heterochromatin.

  18. Somatic mutations found in the healthy blood compartment of a 115-yr-old woman demonstrate oligoclonal hematopoiesis

    Science.gov (United States)

    Holstege, Henne; Pfeiffer, Wayne; Sie, Daoud; Hulsman, Marc; Nicholas, Thomas J.; Lee, Clarence C.; Ross, Tristen; Lin, Jue; Miller, Mark A.; Ylstra, Bauke; Meijers-Heijboer, Hanne; Brugman, Martijn H.; Staal, Frank J.T.; Holstege, Gert; Reinders, Marcel J.T.; Harkins, Timothy T.; Levy, Samuel; Sistermans, Erik A.

    2014-01-01

    The somatic mutation burden in healthy white blood cells (WBCs) is not well known. Based on deep whole-genome sequencing, we estimate that approximately 450 somatic mutations accumulated in the nonrepetitive genome within the healthy blood compartment of a 115-yr-old woman. The detected mutations appear to have been harmless passenger mutations: They were enriched in noncoding, AT-rich regions that are not evolutionarily conserved, and they were depleted for genomic elements where mutations might have favorable or adverse effects on cellular fitness, such as regions with actively transcribed genes. The distribution of variant allele frequencies of these mutations suggests that the majority of the peripheral white blood cells were offspring of two related hematopoietic stem cell (HSC) clones. Moreover, telomere lengths of the WBCs were significantly shorter than telomere lengths from other tissues. Together, this suggests that the finite lifespan of HSCs, rather than somatic mutation effects, may lead to hematopoietic clonal evolution at extreme ages. PMID:24760347

  19. Gearbox Reliability Collaborative: Test and Model Investigation of Sun Orbit and Planet Load Share in a Wind Turbine Gearbox; Preprint

    Energy Technology Data Exchange (ETDEWEB)

    LaCava, W.; Keller, J.; McNiff, B.

    2012-04-01

    This paper analyzes experimental measurement of the sun gear orbit in dynamometer testing and describes its relation to the other measured responses of the planetary stage. The relation of the sun orbit to component runout, component flexibility, gear coupling alignment, planet load share, and planet position error will be investigated. Equations describing the orbit of the sun gear in the test cases are derived. Rigid and flexible multibody models of the full gearbox are investigated and compared to sun and planet measurements. This paper shows that the sun gear's path may be influenced by gear coupling responses and gearbox structural flexibilities.

  20. Quantitative estimation of landslide risk from rapid debris slides on natural slopes in the Nilgiri hills, India

    Directory of Open Access Journals (Sweden)

    P. Jaiswal

    2011-06-01

    Full Text Available A quantitative procedure for estimating landslide risk to life and property is presented and applied in a mountainous area in the Nilgiri hills of southern India. Risk is estimated for elements at risk located in both initiation zones and run-out paths of potential landslides. Loss of life is expressed as individual risk and as societal risk using F-N curves, whereas the direct loss of properties is expressed in monetary terms.

    An inventory of 1084 landslides was prepared from historical records available for the period between 1987 and 2009. A substantially complete inventory was obtained for landslides on cut slopes (1042 landslides, while for natural slopes information on only 42 landslides was available. Most landslides were shallow translational debris slides and debris flowslides triggered by rainfall. On natural slopes most landslides occurred as first-time failures.

    For landslide hazard assessment the following information was derived: (1 landslides on natural slopes grouped into three landslide magnitude classes, based on landslide volumes, (2 the number of future landslides on natural slopes, obtained by establishing a relationship between the number of landslides on natural slopes and cut slopes for different return periods using a Gumbel distribution model, (3 landslide susceptible zones, obtained using a logistic regression model, and (4 distribution of landslides in the susceptible zones, obtained from the model fitting performance (success rate curve. The run-out distance of landslides was assessed empirically using landslide volumes, and the vulnerability of elements at risk was subjectively assessed based on limited historic incidents.

    Direct specific risk was estimated individually for tea/coffee and horticulture plantations, transport infrastructures, buildings, and people both in initiation and run-out areas. Risks were calculated by considering the minimum, average, and maximum landslide volumes in

  1. Quantitative estimation of landslide risk from rapid debris slides on natural slopes in the Nilgiri hills, India

    Science.gov (United States)

    Jaiswal, P.; van Westen, C. J.; Jetten, V.

    2011-06-01

    A quantitative procedure for estimating landslide risk to life and property is presented and applied in a mountainous area in the Nilgiri hills of southern India. Risk is estimated for elements at risk located in both initiation zones and run-out paths of potential landslides. Loss of life is expressed as individual risk and as societal risk using F-N curves, whereas the direct loss of properties is expressed in monetary terms. An inventory of 1084 landslides was prepared from historical records available for the period between 1987 and 2009. A substantially complete inventory was obtained for landslides on cut slopes (1042 landslides), while for natural slopes information on only 42 landslides was available. Most landslides were shallow translational debris slides and debris flowslides triggered by rainfall. On natural slopes most landslides occurred as first-time failures. For landslide hazard assessment the following information was derived: (1) landslides on natural slopes grouped into three landslide magnitude classes, based on landslide volumes, (2) the number of future landslides on natural slopes, obtained by establishing a relationship between the number of landslides on natural slopes and cut slopes for different return periods using a Gumbel distribution model, (3) landslide susceptible zones, obtained using a logistic regression model, and (4) distribution of landslides in the susceptible zones, obtained from the model fitting performance (success rate curve). The run-out distance of landslides was assessed empirically using landslide volumes, and the vulnerability of elements at risk was subjectively assessed based on limited historic incidents. Direct specific risk was estimated individually for tea/coffee and horticulture plantations, transport infrastructures, buildings, and people both in initiation and run-out areas. Risks were calculated by considering the minimum, average, and maximum landslide volumes in each magnitude class and the

  2. R&D on Composition and Processing of Titanium Aluminide Alloys for Turbine Engines

    Science.gov (United States)

    1982-07-01

    heat and T is the temperature in degrees Farenheit , will very accurately predict the value of the specific heat over the afore- mentioned temperature...enthalpy (Btu/ib.), and T is the temperature in degrees Farenheit . Equation 2) was obtained by at least squares, polynomial regression curve fit of data...1500) 0-317 (0-46) 82,S00 413 (60) tEGEND * Runout 380 (65) 344 (01) 0 2 310( 451 276(40) II I 103 104 106 106 Cycles to failure Figure 37. S/N curve

  3. Semiautomated object-based classification of rain-induced landslides with VHR multispectral images on Madeira Island

    OpenAIRE

    Heleno, Sandra; Matias, Magda; Pina, Pedro , (O.F.M.); sousa, António Jorge

    2016-01-01

    A method for semiautomated landslide detection and mapping, with the ability to separate source and run-out areas, is presented in this paper. It combines object-based image analysis and a support vector machine classifier and is tested using a GeoEye-1 multispectral image, sensed 3 days after a major damaging landslide event that occurred on Madeira Island (20 February 2010), and a pre-event lidar digital terrain model. The testing is developed in a 15 km2 wide study area,...

  4. A new look at mobility metrics for pyroclastic density currents: collection, interpretation, and use

    Science.gov (United States)

    Ogburn, S. E.; Lopes, D.; Calder, E. S.

    2012-12-01

    Mitigation of risk associated with pyroclastic density currents (PDCs) depends upon accurate forecasting of possible flow paths, often using empirical models that rely on mobility metrics or the stochastic application of computational flow models. Mobility metrics often inform computational models, sometimes as direct model inputs (e.g. energy cone model), or as estimates for input parameters (e.g. basal friction parameter in TITAN2D). These mobility metrics are often compiled from PDCs at many volcanoes, generalized to reveal empirical constants, or sampled for use in probabilistic models. In practice, however, there are often inconsistencies in how mobility metrics have been collected, reported, and used. For instance, the runout of PDCs often varies depending on the method used (e.g. manually measured from a paper map, automated using GIS software); and the distance traveled by the center of mass of PDCs is rarely reported due to the difficulty in locating it. This work reexamines the way we measure, report, and analyze PDC mobility metrics. Several metrics, such as the Heim coefficient (height dropped/runout, H/L) and the proportionality of inundated area to volume (A∝V2/3) have been used successfully with PDC data (Sparks 1976; Nairn and Self 1977; Sheridan 1979; Hayashi and Self 1992; Calder et al. 1999; Widiwijayanti et al. 2008) in addition to the non-volcanic flows they were originally developed for. Other mobility metrics have been investigated by the debris avalanche community but have not yet been extensively applied to pyroclastic flows (e.g. the initial aspect ratio of collapsing pile). We investigate the relative merits and suitability of contrasting mobility metrics for different types of PDCs (e.g. dome-collapse pyroclastic flows, ash-cloud surges, pumice flows), and indicate certain circumstances under which each model performs optimally. We show that these metrics can be used (with varying success) to predict the runout of a PDC of given volume

  5. Control of Magnetic Bearings for Rotor Unbalance With Plug-In Time-Varying Resonators.

    Science.gov (United States)

    Kang, Christopher; Tsao, Tsu-Chin

    2016-01-01

    Rotor unbalance, common phenomenon of rotational systems, manifests itself as a periodic disturbance synchronized with the rotor's angular velocity. In active magnetic bearing (AMB) systems, feedback control is required to stabilize the open-loop unstable electromagnetic levitation. Further, feedback action can be added to suppress the repeatable runout but maintain closed-loop stability. In this paper, a plug-in time-varying resonator is designed by inverting cascaded notch filters. This formulation allows flexibility in designing the internal model for appropriate disturbance rejection. The plug-in structure ensures that stability can be maintained for varying rotor speeds. Experimental results of an AMB-rotor system are presented.

  6. Optimum design of control system in recoil mechanisms

    Directory of Open Access Journals (Sweden)

    J. P. Sirpal

    1959-07-01

    Full Text Available The various parameters in the design of a control system in a conventional type of recoil mechanism have been optimized for minimum weight and the ideal form of velocity space variation during runout has been derived. A theoretical analysis for some of the equipments in service reveals that their actual values are very nearly the same as those given by theory except for the ratio l by di which are lower than those theoretically suggested indicating that wide margins of safety against buckling have been used in their design.

  7. Debris flow hazard modelling on medium scale: Valtellina di Tirano, Italy

    Directory of Open Access Journals (Sweden)

    J. Blahut

    2010-11-01

    Full Text Available Debris flow hazard modelling at medium (regional scale has been subject of various studies in recent years. In this study, hazard zonation was carried out, incorporating information about debris flow initiation probability (spatial and temporal, and the delimitation of the potential runout areas. Debris flow hazard zonation was carried out in the area of the Consortium of Mountain Municipalities of Valtellina di Tirano (Central Alps, Italy. The complexity of the phenomenon, the scale of the study, the variability of local conditioning factors, and the lacking data limited the use of process-based models for the runout zone delimitation. Firstly, a map of hazard initiation probabilities was prepared for the study area, based on the available susceptibility zoning information, and the analysis of two sets of aerial photographs for the temporal probability estimation. Afterwards, the hazard initiation map was used as one of the inputs for an empirical GIS-based model (Flow-R, developed at the University of Lausanne (Switzerland. An estimation of the debris flow magnitude was neglected as the main aim of the analysis was to prepare a debris flow hazard map at medium scale. A digital elevation model, with a 10 m resolution, was used together with landuse, geology and debris flow hazard initiation maps as inputs of the Flow-R model to restrict potential areas within each hazard initiation probability class to locations where debris flows are most likely to initiate. Afterwards, runout areas were calculated using multiple flow direction and energy based algorithms. Maximum probable runout zones were calibrated using documented past events and aerial photographs. Finally, two debris flow hazard maps were prepared. The first simply delimits five hazard zones, while the second incorporates the information about debris flow spreading direction probabilities, showing areas more likely to be affected by future debris flows. Limitations of the modelling arise

  8. The Geomorphological Evolution of a Landscape in a Tectonically Active Region: the Sennwald Landslide

    Science.gov (United States)

    Aksay, Selçuk; Ivy-Ochs, Susan; Hippe, Kristina; Graemiger, Lorenz; Vockenhuber, Christof

    2016-04-01

    The Säntis nappe is a fold-and-thrust structure in eastern Switzerland consisting of numerous tectonic discontinuities that make rocks vulnerable to rock failure. The Sennwald landslide is one of those events that occurred due to the failure of Lower Cretaceous Helvetic limestones. This study reveals the surface exposure age of the event in relation to geological and tectonic setting, earthquake frequency of the Central Alps, and regional scale climate/weather influence. Our study comprises detailed mapping of landform features, thin section analysis of landslide boulder lithologies, landslide volume estimation, numerical DAN-3D run-out modelling, and the spatial and temporal relationship of the event. In the Sennwald landslide, 92 million m3 of limestones detached from the south-eastern wall of the Säntis nappe and slid with a maximum travel distance of ~4'500 m and a "fahrboeschung" angle of 15° along the SE-dipping sliding plane almost parallel to the orientation of the bedding plane. Numerical run-out modelling results match the extent and the thickness of landslide deposits as observed in the field. The original bedrock stratigraphy was preserved as geologically the top layer in the bedrock package travelled the farthest and the bottom layer came to rest closest to the release bedrock wall during the landslide. Velocities of maximum 90 m/s were obtained from the numerical run-out modelling. Total Cl and 36Cl were determined at ETH AMS facility with isotope dilution methods defined in the literature (Ivy-Ochs et al., 2004). Surface exposure ages of landslide deposits in the accumulation area are revealed from twelve boulders. The distribution of limestone boulders in the accumulation area, the exposure ages, and the numerical run-out modelling support the hypothesis that the Sennwald landslide was a single catastrophic event. The event is likely to have been triggered by at least light to moderate earthquakes (Mw=4.0-6.0). The historical and the last 40-year

  9. Austenite and ferrite grain size evolution in plain carbon steel

    Energy Technology Data Exchange (ETDEWEB)

    Militzer, M.; Giumelli, A.; Hawbolt, E.B.; Meadowcroft, T.R. [British Columbia Univ., Vancouver, BC (Canada)

    1995-01-01

    Grain size evolution in a 0.17%C, 0.74%Mn plain carbon steel is investigated using a Gleeble 1500 thermomechanical simulator. Austenite grain growth measurements in the temperature range from 900 to 1150{degrees}C have been used to validate the Abbruzzese and Luecke model, which is recommended for simulating grain growth during reheating. For run-out table conditions, the ferrite grain size decreases from 1l{mu}m to 4{mu}m when the cooling rate from the austenite is increased from 1 to 80{degrees}C/s.

  10. Next generation spindles for micromilling.

    Energy Technology Data Exchange (ETDEWEB)

    Pathak, Jay P. (Machine Tool Research Center, University of Florida, Gainesville, FL); Payne, Scott W. T. (Machine Tool Research Center, University of Florida, Gainesville, FL); Gill, David Dennis; Ziegert, John C. (Machine Tool Research Center, University of Florida, Gainesville, FL); Jokiel, Bernhard, Jr.

    2004-12-01

    There exists a wide variety of important applications for micro- and meso-scale mechanical systems in the commercial and defense sectors, which require high-strength materials and complex geometries that cannot be produced using current MEMS fabrication technologies. Micromilling has great potential to fill this void in MEMS technology by adding the capability of free form machining of complex 3D shapes from a wide variety and combination of traditional, well-understood engineering alloys, glasses and ceramics. Inefficiencies in micromilling result from the relationships between a cutting tool's breaking strength, the applied cutting force, and the metal removal rate. Because machining times in mesofeatures scale inversely to the part size, a feature 1/10th as large will take 10 times as long to machine. Also, required chip sizes of 1 m or less are cut with tools having edge radius of 2-3 m, the cutting edge effectively has a highly negative rake angle, cutting forces are increased significantly causing chip loads to be further reduced and the machining takes even longer than predicted above. However, cutting forces do not increase with cutting speed, so faster spindles with reduced tool runout are the path to achieve efficient mesoscale milling. This research explored the development of new ultra-high speed micromilling spindles. A novel air-bearing spindle design is discussed that will run at very high speeds (450,000 rpm) and provide very minimal runout allowing the best use of micromilling cutters and reducing overall machining time drastically. Two generations of this spindle design were completed; one with an air bearing supported tool shaft and one with a novel rolling element bearing supported tool shaft. Both designs utilized friction-drive systems that relied on diameter differences between the drive wheel (operating at speeds up to 90,000 rpm) and the tool shaft to achieve high rotational tool speeds. Runout, stiffness, and machining tests were

  11. Fatigue failure of sandwich beams with face sheet wrinkle defects

    DEFF Research Database (Denmark)

    Leong, Martin Klitgaard; Hvejsel, C.F.; Thomsen, Ole Thybo

    2012-01-01

    and application of the Northwestern University failure criteria. The presence of a wrinkle defect reduced the fatigue life by approximately 66%, compared to that of an unnotched reference laminate. Furthermore, the results from the fatigue tests revealed that the design limit was initially overestimated......, as the specimens loaded close to the predicted design limit typically failed before reaching the target life, or reached test run-out with visible face sheet damage indicating imminent final failure in the worst case. It was found that specimens would reach target life with no visible or otherwise detectable...

  12. Element Tracking Strategies for Hot Strip Laminar Cooling Control

    Institute of Scientific and Technical Information of China (English)

    HAN Bin; ZHANG Zhong-ping; LIU Xiang-hua; WANG Guo-dong

    2005-01-01

    Feedforward control is the core to control function in the cooling process of hot strip. One of the most important tasks in feedforward control is to determine the arrival time of the strip at various locations on the runout table for effective control. Based on the principles of element tracking and tracking strategies for variable rolling speed and constant rolling speed, a simple diagonal tracking method for an existing hot strip mill was proposed and tested. The test results show that the proposed strategies are effective for improving tracking control.

  13. Vibration mechanism analysis and dynamic model development of magnetically suspended rigid rotor system%磁悬浮刚性转子系统振动机理分析与动力学建模

    Institute of Scientific and Technical Information of China (English)

    房建成; 张会娟; 刘虎

    2014-01-01

    By the virtue of active magnetic bearing, magnetically suspended inertia actuators can make micro-vibration come true through active vibration control. However, there still exist vibrations with some frequencies in magnetically suspended inertia actuators. Firstly, the vibration mechanism of Magnet Runout is analyzed based on the analysis of rotor unbalance and Sensor Runout, then the dynamic model of the magnetically suspended rigid rotor system composing of three vibration sources is developed and divided into translational motion and torsional motion. The analysis dedicates that rotor unbalance, Magnet Runout and Sensor Runout will arise vibrations through different channels, and that the vibrations include the fundamental frequencies and their harmonics. Lastly, the requirements of active vibration control are proposed for the magnetically suspended rigid rotor system, and are useful for the future research.%磁悬浮惯性执行机构采用磁轴承支承,可通过主动控制实现极微振动,但磁悬浮惯性执行机构仍存在频谱分量丰富的振动。首先在转子动静不平衡和Sensor Runout振动机理分析的基础上,重点分析了Magnet Runout产生振动机理;然后,建立包含多振动源的系统动力学建模,并将整个动力学模型分解为平动和转动子系统,分析表明转子动静不平衡、Sensor Runout和Magnet Runout是通过不同的途径产生振动,不仅产生同频振动还包含倍频振动;最后,提出磁悬浮刚性转子系统主动振动控制的要求,为以后的主动振动控制研究奠定基础。

  14. Triggering conditions and mobility of debris flows associated to complex earthflows

    Science.gov (United States)

    Malet, J.-P.; Laigle, D.; Remaître, A.; Maquaire, O.

    2005-03-01

    Landslides on black marl slopes of the French Alps are, in most cases, complex catastrophic failures in which the initial structural slides transform into slow-moving earthflows. Under specific hydrological conditions, these earthflows can transform into debris flows. Due to their sediment volume and their high mobility, debris flow induced by landslides are far much dangerous than these resulting from continuous erosive processes. A fundamental point to correctly delineate the area exposed to debris flows on the alluvial fans is therefore to understand why and how some earthflows transform into debris flow while most of them stabilize. In this paper, a case of transformation from earthflow to debris flow is presented and analysed. An approach combining geomorphology, hydrology, geotechnics and rheology is adopted to model the debris flow initiation (failure stage) and its runout (postfailure stage). Using the Super-Sauze earthflow (Alpes-de-Haute-Provence, France) as a case study, the objective is to characterize the hydrological and mechanical conditions leading to debris flow initiation in such cohesive material. Results show a very good agreement between the observed runout distances and these calculated using the debris flow modeling code Cemagref 1-D. The deposit thickness in the depositional area and the velocities of the debris flows are also well reproduced. Furthermore, a dynamic slope stability analysis shows that conditions in the debris source area under average pore water pressures and moisture contents are close to failure. A small excess of water can therefore initiate failure. Seepage analysis is used to estimate the volume of debris that can be released for several hydroclimatic conditions. The failed volumes are then introduced in the Cemagref 1-D runout code to propose debris flow hazard scenarios. Results show that clayey earthflow can transform under 5-year return period rainfall conditions into 1-km runout debris flow of volumes ranging

  15. Lithofacies, biofacies, and ichnoassemblage evolution of a shallow submarine volcaniclastic fan-shelf depositional system (Upper Cretaceous, James Ross Island, Antarctica)

    Science.gov (United States)

    Scasso, R. A.; Olivero, E. B.; Buatois, L. A.

    The Upper Cretaceous (Santonian-Campanian/lower Maastrichtian) Santa Marta Formation on James Ross Island, Antarctica, represents volcaniclastic shallow marine fan and shelf sedimentation adjacent to an active volcanic arc. A combined analysis of sedimentologic, paleoecologic, and ichnologic data allows for the recognition in this unit of six lithofacies associations, eight biofacies, and five trace fossils assemblages. Lithofacies are dominated by fine, massive, tuffaceous rocks; graded, turbidite-like tuffaceous sandstones; carbonaceous mudstones; resedimented conglomerates; coquinas; sandstones; silty sandstones; and minor stromatolite beds. Biofacies are defined by different composition and relative abundance of elements of the benthic fauna, mainly bivalves, gastropods, and serpulids, with minor elements represented by scaphopods, corals, brachiopods, and echinoids. Trace fossil assemblages include the most common elements of the Skolithos and Cruziana ichnofacies. A striking result of the analysis is that lithofacies, biofacies, and trace fossil assemblages form distinct, non-repetitive, vertically successive horizons, with their distribution boundaries roughly coincident. On this basis, seven major facies groups, showing a distinct combination of lithofacies, biofacies, and trace fossils, are distinguished in the Santa Marta Formation. These non-repetitive, vertically stacked facies groups reveal a one-way evolution of the depositional system during a transgressive-regressive cycle, with a new transgression at the top of the unit. The lower facies groups represent shallow marine settings with a very high rate of volcaniclastic sedimentation within subsiding basin. Shallow, volcaniclastic fan systems were probably formed at the base of delta slope and grew rapidly as a consequence of high sedimentary supply in equilibrium with basin subsidence. The upper facies groups probably represent sedimentation within the marine part of the envisaged deltaic system on a

  16. An ancient repeat sequence in the ATP synthase beta-subunit gene of forcipulate sea stars.

    Science.gov (United States)

    Foltz, David W

    2007-11-01

    A novel repeat sequence with a conserved secondary structure is described from two nonadjacent introns of the ATP synthase beta-subunit gene in sea stars of the order Forcipulatida (Echinodermata: Asteroidea). The repeat is present in both introns of all forcipulate sea stars examined, which suggests that it is an ancient feature of this gene (with an approximate age of 200 Mya). Both stem and loop regions show high levels of sequence constraint when compared to flanking nonrepetitive intronic regions. The repeat was also detected in (1) the family Pterasteridae, order Velatida and (2) the family Korethrasteridae, order Velatida. The repeat was not detected in (1) the family Echinasteridae, order Spinulosida, (2) the family Astropectinidae, order Paxillosida, (3) the family Solasteridae, order Velatida, or (4) the family Goniasteridae, order Valvatida. The repeat lacks similarity to published sequences in unrestricted GenBank searches, and there are no significant open reading frames in the repeat or in the flanking intron sequences. Comparison via parametric bootstrapping to a published phylogeny based on 4.2 kb of nuclear and mitochondrial sequence for a subset of these species allowed the null hypothesis of a congruent phylogeny to be rejected for each repeat, when compared separately to the published phylogeny. In contrast, the flanking nonrepetitive sequences in each intron yielded separate phylogenies that were each congruent with the published phylogeny. In four species, the repeat in one or both introns has apparently experienced gene conversion. The two introns also show a correlated pattern of nucleotide substitutions, even after excluding the putative cases of gene conversion.

  17. High-resolution mapping and transcriptional activity analysis of chicken centromere sequences on giant lampbrush chromosomes.

    Science.gov (United States)

    Krasikova, Alla; Fukagawa, Tatsuo; Zlotina, Anna

    2012-12-01

    Exploration into morphofunctional organisation of centromere DNA sequences is important for understanding the mechanisms of kinetochore specification and assembly. In-depth epigenetic analysis of DNA fragments associated with centromeric nucleosome proteins has demonstrated unique features of centromere organisation in chicken karyotype: there are both mature centromeres, which comprise chromosome-specific homogeneous arrays of tandem repeats, and recently evolved primitive centromeres, which consist of non-tandemly organised DNA sequences. In this work, we describe the arrangement and transcriptional activity of chicken centromere repeats for Cen1, Cen2, Cen3, Cen4, Cen7, Cen8, and Cen11 and non-repetitive centromere sequences of chromosomes 5, 27, and Z using highly elongated lampbrush chromosomes, which are characteristic of the diplotene stage of oogenesis. The degree of chromatin packaging and fine spatial organisations of tandemly repetitive and non-tandemly repetitive centromeric sequences significantly differ at the lampbrush stage. Using DNA/RNA FISH, we have demonstrated that during the lampbrush stage, DNA sequences are transcribed within the centromere regions of chromosomes that lack centromere-specific tandem repeats. In contrast, chromosome-specific centromeric repeats Cen1, Cen2, Cen3, Cen4, Cen7, Cen8, and Cen11 do not demonstrate any transcriptional activity during the lampbrush stage. In addition, we found that CNM repeat cluster localises adjacent to non-repetitive centromeric sequences in chicken microchromosome 27 indicating that centromere region in this chromosome is repeat-rich. Cross-species FISH allowed localisation of the sequences homologous to centromeric DNA of chicken chromosomes 5 and 27 in centromere regions of quail orthologous chromosomes.

  18. Design optimization methods for genomic DNA tiling arrays.

    Science.gov (United States)

    Bertone, Paul; Trifonov, Valery; Rozowsky, Joel S; Schubert, Falk; Emanuelsson, Olof; Karro, John; Kao, Ming-Yang; Snyder, Michael; Gerstein, Mark

    2006-02-01

    A recent development in microarray research entails the unbiased coverage, or tiling, of genomic DNA for the large-scale identification of transcribed sequences and regulatory elements. A central issue in designing tiling arrays is that of arriving at a single-copy tile path, as significant sequence cross-hybridization can result from the presence of non-unique probes on the array. Due to the fragmentation of genomic DNA caused by the widespread distribution of repetitive elements, the problem of obtaining adequate sequence coverage increases with the sizes of subsequence tiles that are to be included in the design. This becomes increasingly problematic when considering complex eukaryotic genomes that contain many thousands of interspersed repeats. The general problem of sequence tiling can be framed as finding an optimal partitioning of non-repetitive subsequences over a prescribed range of tile sizes, on a DNA sequence comprising repetitive and non-repetitive regions. Exact solutions to the tiling problem become computationally infeasible when applied to large genomes, but successive optimizations are developed that allow their practical implementation. These include an efficient method for determining the degree of similarity of many oligonucleotide sequences over large genomes, and two algorithms for finding an optimal tile path composed of longer sequence tiles. The first algorithm, a dynamic programming approach, finds an optimal tiling in linear time and space; the second applies a heuristic search to reduce the space complexity to a constant requirement. A Web resource has also been developed, accessible at http://tiling.gersteinlab.org, to generate optimal tile paths from user-provided DNA sequences.

  19. Elimination of Harmonic Force and Torque in Active Magnetic Bearing Systems with Repetitive Control and Notch Filters.

    Science.gov (United States)

    Xu, Xiangbo; Chen, Shao; Liu, Jinhao

    2017-04-04

    Harmonic force and torque, which are caused by rotor imbalance and sensor runout, are the dominant disturbances in active magnetic bearing (AMB) systems. To eliminate the harmonic force and torque, a novel control method based on repetitive control and notch filters is proposed. Firstly, the dynamics of a four radial degrees of freedom AMB system is described, and the AMB model can be described in terms of the translational and rotational motions, respectively. Next, a closed-loop generalized notch filter is utilized to identify the synchronous displacement resulting from the rotor imbalance, and a feed-forward compensation of the synchronous force and torque related to the AMB displacement stiffness is formulated by using the identified synchronous displacement. Then, a plug-in repetitive controller is designed to track the synchronous feed-forward compensation adaptively and to suppress the harmonic vibrations due to the sensor runout. Finally, the proposed control method is verified by simulations and experiments. The control algorithm is insensitive to the parameter variations of the power amplifiers and can precisely suppress the harmonic force and torque. Its practicality stems from its low computational load.

  20. Berm design to reduce risks of catastrophic slope failures at solid waste disposal sites.

    Science.gov (United States)

    De Stefano, Matteo; Gharabaghi, Bahram; Clemmer, Ryan; Jahanfar, M Ali

    2016-11-01

    Existing waste disposal sites are being strained by exceeding their volumetric capacities because of exponentially increasing rates of municipal solid waste generation worldwide, especially in densely populated metropolises. Over the past 40 years, six well-documented and analyzed disposal sites experienced catastrophic failure. This research presents a novel analysis and design method for implementation of a series of in-situ earth berms to slow down the movement of waste material flow following a catastrophic failure. This is the first study of its kind that employs a dynamic landslide analysis model, DAN-W, and the Voellmy rheological model to approximate solid waste avalanche flow. A variety of single and multiple berm configuration scenarios were developed and tested to find an optimum configuration of the various earth berm geometries and number of berms to achieve desired energy dissipation and reduction in total waste material runout length. The case study application of the novel mitigation measure shows that by constructing a series of six relatively inexpensive 3 m high earth berms at an optimum distance of 250 m from the slope toe, the total runout length of 1000 m and associated fatalities of the Leuwigajah dumpsite catastrophic failure in Bandung, Indonesia, could have been reduced by half. © The Author(s) 2016.

  1. Failure Mechanism of True 2D Granular Flows

    CERN Document Server

    Nguyen, Cuong T; Fukagawa, R

    2015-01-01

    Most previous experimental investigations of two-dimensional (2D) granular column collapses have been conducted using three-dimensional (3D) granular materials in narrow horizontal channels (i.e., quasi-2D condition). Our recent research on 2D granular column collapses by using 2D granular materials (i.e., aluminum rods) has revealed results that differ markedly from those reported in the literature. We assume a 2D column with an initial height of h0 and initial width of d0, a defined as their ratio (a =h0/d0), a final height of h , and maximum run-out distance of d . The experimental data suggest that for the low a regime (a 0.65), the ratio of a to (d-d0)/d0, h0/h , or d/d0 is expressed by power-law relations. In particular, the following power-function ratios (h0/h=1.42a^2/3 and d/d0=4.30a^0.72) are proposed for every a >0.65. In contrast, the ratio (d-d0)/d0=3.25a^0.96 only holds for 0.651.5. In addition, the influence of ground contact surfaces (hard or soft beds) on the final run-out distance and destru...

  2. Landslides triggered by April 2016 Kumamoto Earthquake, Japan

    Science.gov (United States)

    Fukuoka, Hiroshi; Bhoopendra, Dabycharun; Sakai, Naoki; Sassa, Kyoji; Dang, Khang

    2017-04-01

    Kumamoto prefecture, Japan was rattled by consecutive earthquakes of M6.5 on April 14 and M7.3 on April 16, 2016. These unusual fore-shock and main-shock claimed fifty casualties, of which ten persons were killed by landslides. The second quake recorded maximum PGA of 1,362 gal, and triggered a number of landslides around Mt. Aso, an active volcano with one of the largest scale caldera. Geospatial Information Authority of Japan interpreted airphotos of the affected area and found at least 750 landslides. Based on the reconnaissance and joint field investigation of ICL and the Japan Landslide Society, those landslides are classified into following 3 types; (1) shallow and deep disrupted landslides on steep slopes mostly on the caldera rim or cliffs, (2) deep-seated and fluidized landslides on gentler slopes showing long run-out distance; (3) debris flows without antecedent precipitation. Soil sampled from landslide sites showed higher maximum moisture content values which 100 - 200 %. It is contributed by heavily weathered "kuroboku" soils containing halloysites. Constant volume direct shear tests and undrained cyclic loading ring shear tests were conducted to reveal their long run-out mechanism.

  3. PREDICTION OF CARBON CONCENTRATION AND FERRITE VOLUME FRACTION OF HOT-ROLLED STEEL STRIP DURING LAMINAR COOLING

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    A phase transformation model was presented for predicting the phase fraction transformed and the carbon concentration in austenite for austenite to ferrite transformation during laminar cooling on run-out table in hot rolling strip mill. In this model, the parameter k in Avrami equation was developed for carbon steels. The wide range of chemical composition, the primary austenite grain size, and the retained strain were taken into account. It can be used to predict the ferrite volume fraction and the carbon concentration in austenite of hot-rolled steel strip during laminar cooling on run-out table. The coiling temperature controlling model was also presented to calculate the temperature of steel strip. The transformation kinetics of austenite to ferrite and the evolution of carbon concentration in austenite at different temperatures during cooling were investigated in the hot rolled Q235B strip for thickness of 9.35, 6.4, and 3.2mm. The ferrite volume fraction along the length of the strip was also calculated. The calculated ferrite volume fraction was compared with the log data from hot strip mill and the calculated results were in agreement with the experimental ones. The present study is a part of the prediction of the mechanical properties of hot-rolled steel strip, and it has already been used on-line and off-line in the hot strip mill.

  4. Modelling landslide liquefaction, mobility bifurcation and the dynamics of the 2014 Oso disaster

    Science.gov (United States)

    Iverson, Richard M.; George, David L.

    2016-01-01

    Some landslides move slowly or intermittently downslope, but others liquefy during the early stages of motion, leading to runaway acceleration and high-speed runout across low-relief terrain. Mechanisms responsible for this disparate behaviour are represented in a two-phase, depth-integrated, landslide dynamics model that melds principles from soil mechanics, granular mechanics and fluid mechanics. The model assumes that gradually increasing pore-water pressure causes slope failure to nucleate at the weakest point on a basal slip surface in a statically balanced mass. Failure then spreads to adjacent regions as a result of momentum exchange. Liquefaction is contingent on pore-pressure feedback that depends on the initial soil state. The importance of this feedback is illustrated by using the model to study the dynamics of a disastrous landslide that occurred near Oso, Washington, USA, on 22 March 2014. Alternative simulations of the event reveal the pronounced effects of a landslide mobility bifurcation that occurs if the initial void ratio of water-saturated soil equals the lithostatic, critical-state void ratio. They also show that the tendency for bifurcation increases as the soil permeability decreases. The bifurcation implies that it can be difficult to discriminate conditions that favour slow landsliding from those that favour liquefaction and long runout.

  5. The aureole of Olympus Mons (Mars) as the compound deposit of submarine landslides

    Science.gov (United States)

    De Blasio, Fabio Vittorio

    2011-12-01

    The enigmatic deposits building up the Olympus Mons aureole on Mars are likely among the largest landslide remnants in the Solar System. These deposits exhibit an extraordinary run-out distance (up to nearly 700 km), in spite of a fall height some 100 times smaller. After quantifying the mobility of the Olympus Mons aureole lobes it is suggested, based on dynamical considerations and morphological analysis, that the aureole could be the consequence of a series of gigantic subaqueous landslides. In order to bring evidence in favor of this interpretation, comparisons are drawn between the different landslide deposits on Earth and Mars, emphasizing the similarity with the rock avalanches of the Canary Islands and the Hawaii. The results of experimental subaqueous debris flows are also analyzed, and numerical calculations are introduced to simulate the dynamics of flow. In analogy with certain subaqueous landslides on Earth, it is possible that the outstanding run-out of the aureole lobes was a consequence of hydroplaning, a natural lubrication by water during flow.

  6. Acoustic fluidization - A new geologic process

    Science.gov (United States)

    Melosh, H. J.

    1979-01-01

    A number of geologic processes, particularly seismic faulting, impact crater slumping, and long runout landslides, require the failure of geologic materials under differential stresses much smaller than expected on the basis of conventional rock mechanics. This paper proposes that the low strengths apparent in these phenomena are due to a state of 'acoustic fluidization' induced by a transient strong acoustic wave field. The strain rates possible in such a field are evaluated, and it is shown that acoustically fluidized debris behaves as a newtonian fluid with a viscosity in the range 100,000 to 10,000,000 P for plausible conditions. Energy gains and losses in the acoustic field are discussed, and the mechanism is shown to be effective if internal dissipation in the field gives a Q approximately greater than 100. Whether such values for Q are realized is not known at present. However, acoustic fluidization provides a qualitatively correct description of the failure of rock debris under low differential stresses in the processes of faulting, crater slumping, and long runout landslides. Acoustic fluidization thus deserves serious consideration as a possible explanation of these phenomena.

  7. Elimination of Harmonic Force and Torque in Active Magnetic Bearing Systems with Repetitive Control and Notch Filters

    Directory of Open Access Journals (Sweden)

    Xiangbo Xu

    2017-04-01

    Full Text Available Harmonic force and torque, which are caused by rotor imbalance and sensor runout, are the dominant disturbances in active magnetic bearing (AMB systems. To eliminate the harmonic force and torque, a novel control method based on repetitive control and notch filters is proposed. Firstly, the dynamics of a four radial degrees of freedom AMB system is described, and the AMB model can be described in terms of the translational and rotational motions, respectively. Next, a closed-loop generalized notch filter is utilized to identify the synchronous displacement resulting from the rotor imbalance, and a feed-forward compensation of the synchronous force and torque related to the AMB displacement stiffness is formulated by using the identified synchronous displacement. Then, a plug-in repetitive controller is designed to track the synchronous feed-forward compensation adaptively and to suppress the harmonic vibrations due to the sensor runout. Finally, the proposed control method is verified by simulations and experiments. The control algorithm is insensitive to the parameter variations of the power amplifiers and can precisely suppress the harmonic force and torque. Its practicality stems from its low computational load.

  8. Creep Behavior in Interlaminar Shear of a SiC/SiC Ceramic Composite with a Self-healing Matrix

    Science.gov (United States)

    Ruggles-Wrenn, M. B.; Pope, M. T.

    2014-02-01

    Creep behavior in interlaminar shear of a non-oxide ceramic composite with a multilayered matrix was investigated at 1,200 °C in laboratory air and in steam environment. The composite was produced via chemical vapor infiltration (CVI). The composite had an oxidation inhibited matrix, which consisted of alternating layers of silicon carbide and boron carbide and was reinforced with laminated Hi-Nicalon™ fibers woven in a five-harness-satin weave. Fiber preforms had pyrolytic carbon fiber coating with boron carbide overlay applied. The interlaminar shear properties were measured. The creep behavior was examined for interlaminar shear stresses in the 16-22 MPa range. Primary and secondary creep regimes were observed in all tests conducted in air and in steam. In air and in steam, creep run-out defined as 100 h at creep stress was achieved at 16 MPa. Larger creep strains were accumulated in steam. However, creep strain rates and creep lifetimes were only moderately affected by the presence of steam. The retained properties of all specimens that achieved run-out were characterized. Composite microstructure, as well as damage and failure mechanisms were investigated.

  9. A revision of the Haiming rock avalanche (Eastern Alps)

    Science.gov (United States)

    Dufresne, Anja; Ostermann, Marc; Kelfoun, Karim; Ring, Max; Asam, Dario; Prager, Christoph

    2016-04-01

    The carbonate Haiming rock avalanche is directly neighbouring the larger Tschirgant rock avalanche deposit, both located in the upper Inn valley (Tyrol, Austria). Based on detailed morpho-lithologic mapping of the deposit, which has not been done at Haiming before, the sedimentology of the Holocene landslide debris is characterised. Structural-tectonic elements of the bedrock units at the scarp area are supplemented with borehole data from drillings at the source area giving valuable insights into the complex geological bedrock composition and structure. New source and runout reconstructions allow updated volumetric calculations, which are subsequently integrated into numerical runout modelling. Haiming is one of few topographically unobstructed rock avalanches, yet its morphology was greatly influenced by fluvial terraces, which are still discernible through the deposit on LiDAR hillshade images. We also address the influence of the rock avalanche on the valley floor and local river system as a short-lived dam and its interaction with fluvial incision. Finally, we discuss the Haiming rock avalanche in view of the other massive rock slope failures in the area ("Fernpass cluster"), their spatio-temporal distribution, and point out further highlights of this simple(?) rock avalanche deposit.

  10. Particle flow and segregation in a giant landslide event triggered by the 2008 Wenchuan earthquake, Sichuan, China

    Directory of Open Access Journals (Sweden)

    L. M. Zhang

    2011-04-01

    Full Text Available During the 12 May 2008 Wenchuan earthquake, a large landslide of approximately 30 million m3 occurred at Donghekou with a particle run-out distance of over 2000 m. This paper presents fascinating particle flow and segregation characteristics in the landslide process found through field investigation of changes in the soil particle size, density, and fabric along the particle movement paths. The soil particles experienced projection, long-distance flying, sliding, and rolling. Trajectory segregation, inverse grading, and particle crushing were found in the landslide event, which contributed to the heterogeneity of the soil deposits. In the initial deposition area, particles with larger diameters appeared to have flown longer. Materials from different sources mixed, forming more uniform debris. In the run-out area, the particle flow tended to cause large particles to travel further. However, particle disintegration and crushing led to more small particles along the movement paths and the observed characteristic flow distances of very large particles did not increase with the particle diameter, which is different from observations of an idealized granular mass flow.

  11. Debris avalanches and debris flows transformed from collapses in the Trans-Mexican Volcanic Belt, Mexico - behavior, and implications for hazard assessment

    Science.gov (United States)

    Capra, L.; Macías, J. L.; Scott, K. M.; Abrams, M.; Garduño-Monroy, V. H.

    2002-03-01

    Volcanoes of the Trans-Mexican Volcanic Belt (TMVB) have yielded numerous sector and flank collapses during Pleistocene and Holocene times. Sector collapses associated with magmatic activity have yielded debris avalanches with generally limited runout extent (e.g. Popocatépetl, Jocotitlán, and Colima volcanoes). In contrast, flank collapses (smaller failures not involving the volcano summit), both associated and unassociated with magmatic activity and correlating with intense hydrothermal alteration in ice-capped volcanoes, commonly have yielded highly mobile cohesive debris flows (e.g. Pico de Orizaba and Nevado de Toluca volcanoes). Collapse orientation in the TMVB is preferentially to the south and northeast, probably reflecting the tectonic regime of active E-W and NNW faults. The differing mobilities of the flows transformed from collapses have important implications for hazard assessment. Both sector and flank collapse can yield highly mobile debris flows, but this transformation is more common in the cases of the smaller failures. High mobility is related to factors such as water content and clay content of the failed material, the paleotopography, and the extent of entrainment of sediment during flow (bulking). The ratio of fall height to runout distance commonly used for hazard zonation of debris avalanches is not valid for debris flows, which are more effectively modeled with the relation inundated area to failure or flow volume coupled with the topography of the inundated area.

  12. Assessment of debris-flow susceptibility at medium-scale in the Barcelonnette Basin, France

    Directory of Open Access Journals (Sweden)

    M. S. Kappes

    2011-02-01

    Full Text Available Debris flows are among the most dangerous processes in mountainous areas due to their rapid rate of movement and long runout zone. Sudden and rather unexpected impacts produce not only damages to buildings and infrastructure but also threaten human lives. Medium- to regional-scale susceptibility analyses allow the identification of the most endangered areas and suggest where further detailed studies have to be carried out. Since data availability for larger regions is mostly the key limiting factor, empirical models with low data requirements are suitable for first overviews. In this study a susceptibility analysis was carried out for the Barcelonnette Basin, situated in the southern French Alps. By means of a methodology based on empirical rules for source identification and the empirical angle of reach concept for the 2-D runout computation, a worst-case scenario was first modelled. In a second step, scenarios for high, medium and low frequency events were developed. A comparison with the footprints of a few mapped events indicates reasonable results but suggests a high dependency on the quality of the digital elevation model. This fact emphasises the need for a careful interpretation of the results while remaining conscious of the inherent assumptions of the model used and quality of the input data.

  13. Pyroclastic flows generated by gravitational instability of the 1996-97 lava dome of Soufriere Hills Volcano, Montserrat

    Science.gov (United States)

    Cole, P.D.; Calder, E.S.; Druitt, T.H.; Hoblitt, R.; Robertson, R.; Sparks, R.S.J.; Young, S.R.

    1998-01-01

    Numerous pyroclastic flows were produced during 1996-97 by collapse of the growing andesitic lava dome at Soufriere Hills Volcano, Montserrat. Measured deposit volumes from these flows range from 0.2 to 9 ?? 106 m3. Flows range from discrete, single pulse events to sustained large scale dome collapse events. Flows entered the sea on the eastern and southern coasts, depositing large fans of material at the coast. Small runout distance (surge component was enhanced during the larger sustained events. Periods of elevated pyroclastic flow productivity and sustained dome collapse events are linked to pulses of high magma extrusion rates.Numerous pyroclastic flows were produced during 1996-97 by collapse of the growing andesitic lava dome at Soufriere Hills Volcano, Montserrat. Measured deposit volumes from these flows range from 0.2 to 9??106 m3. Flows range from discrete, single pulse events to sustained large scale dome collapse events. Flows entered the sea on the eastern and southern coasts, depositing large fans of material at the coast. Small runout distance (surge component was enhanced during the larger sustained events. Periods of elevated dome pyroclastic flow productivity and sustained collapse events are linked to pulses of high magma extrusion rates.

  14. Research on accuracy of vertical lathe table%立车工作台精度的研究

    Institute of Scientific and Technical Information of China (English)

    谭德宁; 林盛; 张桂欣

    2012-01-01

    This article carries out analysis on axial runout and radial runout of vertical lathe table, the hydrostatic base ways surface and the upright degree of positioning hole, the article puts forward reasons of over tolerance , discusses specific structure of the table scraping frock, from the assembly process, it is solved which the hydrostatic ways surface and the positioning hole upright degree is over tolerance, ensure accuracy of the rotary table from the source.%通过对立车工作台端面跳动与径向跳动误差的分析,提出了底座静压导轨面与定位孔垂直度误差超差的原因,论述了工作台刮研胎具的具体结构,从装配工艺上解决静压导轨面与定位孔垂直度超差的问题,由此从根源上保证工作台的回转精度.

  15. Tension-Compression Fatigue of a Nextel™720/alumina Composite at 1200 °C in Air and in Steam

    Science.gov (United States)

    Lanser, R. L.; Ruggles-Wrenn, M. B.

    2016-08-01

    Tension-compression fatigue behavior of an oxide-oxide ceramic-matrix composite was investigated at 1200 °C in air and in steam. The composite is comprised of an alumina matrix reinforced with Nextel™720 alumina-mullite fibers woven in an eight harness satin weave (8HSW). The composite has no interface between the fiber and matrix, and relies on the porous matrix for flaw tolerance. Tension-compression fatigue behavior was studied for cyclical stresses ranging from 60 to 120 MPa at a frequency of 1.0 Hz. The R ratio (minimum stress to maximum stress) was -1.0. Fatigue run-out was defined as 105 cycles and was achieved at 80 MPa in air and at 70 MPa in steam. Steam reduced cyclic lives by an order of magnitude. Specimens that achieved fatigue run-out were subjected to tensile tests to failure to characterize the retained tensile properties. Specimens subjected to prior cyclic loading in air retained 100 % of their tensile strength. The steam environment severely degraded tensile properties. Tension-compression cyclic loading was considerably more damaging than tension-tension cyclic loading. Composite microstructure, as well as damage and failure mechanisms were investigated.

  16. Multi temporal LiDAR-DTMs as a tool for modelling a complex landslide: a case study in the Rotolon catchment (Eastern Italian Alps)

    Science.gov (United States)

    Bossi, G.; Cavalli, M.; Crema, S.; Frigerio, S.; Luna, B. Quan; Mantovani, M.; Marcato, G.; Schenato, L.; Pasuto, A.

    2014-10-01

    The geomorphological change detection through the comparison of repeated topographic surveys is a recent approach that benefits greatly from the latest developments in topographical data acquisition techniques. Among them, airborne LiDAR makes the monitoring of geomorphological changes a more reliable and accurate approach for natural hazard and risk management. In this study, two LiDAR-DTMs (2 m resolution) were acquired just before and after a complex 340 000 m3 landslide event (4 November 2010) that generated a debris flow in the channel of the Rotolon catchment (Eastern Italian Alps). The analysis of these data was used to set up the initial condition for the application of a dynamic model. The comparison between the pre- and post-event DTMs allowed to identify erosion and depositional areas and the volume of the landslide. The knowledge of the phenomenon dynamics was the base of a sound back-analysis of the event with the 3-D numerical model DAN3D. This particular code was selected for its capability to modify the rheology and the parameters of the moving mass during run-out, as actually observed along the path of the 2010 debris flow. Nowadays some portions of Mt. Rotolon flank are still moving and show signs of detachment. The same soil parameters used in the back-analysis model could be used to simulate the run-out for possible future landslides allowing to generate reliable risk scenarios useful for awareness of civil defense and strategy on emergency plans.

  17. Investigation of the Dispersion Behavior of Inertial Particles within Accelerated Domain

    Directory of Open Access Journals (Sweden)

    Tong ZHAO

    2015-01-01

    Full Text Available This report presents a study of the dynamics dispersion behaviors of inertial particle in solid-air two-phase flow within accelerated domains using both experimental and simulation approaches. In the simulation, a threedimensional model was proposed by means of the combined computational fluid dynamics and a discrete element method (CFD-DEM. The simulation model provides information regarding the particle distribution behaviors and the particle run-away rate from the calculation domain. In the experiment, particle image velocimetry (PIV and laser tomography were used to measure the particle velocity and concentration distribution, respectively. The simulation results were than validated by the experimental measurement. And the influence mechanisms of acceleration on the particle flow behavior were discussed in detail. As results, acceleration of the calculation domain affects the particle motion and causes a relative dense particles distribution in the accelerated direction. The particle run-out rate under acceleration was initially the same, but subsequently lower than that of the condition without acceleration. This finding shows that the acceleration adversely affects the particle run-out rate.

  18. Creep behavior in interlaminar shear of a Hi-Nicalon™/SiC–B{sub 4}C composite at 1200 °C in air and in steam

    Energy Technology Data Exchange (ETDEWEB)

    Ruggles-Wrenn, M.B., E-mail: marina.ruggles-wrenn@afit.edu; Pope, M.T.; Zens, T.W.

    2014-07-29

    Creep behavior in interlaminar shear of a non-oxide ceramic composite with a multilayered matrix was investigated at 1200 °C in laboratory air and in steam environment. The composite was produced via chemical vapor infiltration (CVI). The composite had an oxidation inhibited matrix, which consisted of alternating layers of silicon carbide and boron carbide and was reinforced with laminated Hi-Nicalon™ fibers woven in a five-harness-satin weave. Fiber preforms had pyrolytic carbon fiber coating with boron carbon overlay applied. The interlaminar shear properties were measured. The creep behavior was examined for interlaminar shear stresses in the 16–22 MPa range. Primary and secondary creep regimes were observed in all tests conducted in air and in steam. In air and in steam, creep run-out defined as 100 h at creep stress was achieved at 16 MPa. Similar creep strains were accumulated in air and in steam. Furthermore, creep strain rates and creep lifetimes were only moderately affected by the presence of steam. The retained properties of all specimens that achieved run-out were characterized. Composite microstructure, as well as damage and failure mechanisms were investigated. The tested specimens were also examined using electron probe microanalysis (EPMA) with wavelength dispersive spectroscopy (WDS). Analysis of the fracture surfaces revealed significant surface oxidation, but only trace amounts of boron and carbon. Cross sectional analysis showed increasing boron concentration in the specimen interior.

  19. A model of mudflow propagation downstream from the Grohovo landslide near the city of Rijeka (Croatia)

    Science.gov (United States)

    Žic, E.; Arbanas, Ž.; Bićanić, N.; Ožanić, N.

    2014-11-01

    Mudflows regularly generate significant human and property losses. Analyzing mudflows is important to assess the risks and to delimit vulnerable areas where mitigation measures are required. In recent decades, modeling of the propagation stage has been largely performed within the framework of continuum mechanics, and a number of new and sophisticated computational models have been developed. Most of the available approaches treat the heterogeneous and multiphase moving mass as a single-phase continuum. The smoothed particle hydrodynamics model (SPH model) adopted here considers, in two phases, a granular skeleton with voids filled with either water or mud. The SPH depth integrated numerical model (Pastor et al., 2009a) used for the present simulations is a 2-D model capable of predicting the runout distance, flow velocity, deposition pattern and the final volume of mudflows. It is based on mathematical and rheological models. In this study, the main characteristics of mudflow processes that have emerged in the past in the area downstream of the Grohovo landslide are examined, and the more relevant parameters and attributes describing the mudflow are presented. Principal equations that form the basis of the SPH depth integrated model are reviewed and applied to analyze the Grohovo landslide and the propagation of the mudflow wave downstream of the landslide. Based on the SPH method, the runout distance, quantities of the deposited materials and the velocity of mudflow progression which occurred in the past at the observed area are analysed and qualitatively compared to the recorded consequences of the actual event.

  20. Influence of number of dental autoclave treatment cycles on rotational performance of commercially available air-turbine handpieces.

    Science.gov (United States)

    Nagai, Masahiro; Takakuda, Kazuo

    2006-06-01

    The influence of number of autoclave treatment cycles (N) on rotational speed and total indicated run-out of commercially available air-turbine handpieces from five manufacturers was investigated at N=0, 50, 100, 150, 200, 250 and 300 cycles, and the significance in the test results was assessed by Dunnett's multiple comparison test. Some air-turbine handpieces showed the significant differences in rotational speed at N=300 cycles, however, the decreases of the rotational speeds were only 1 to 3.5 percent. Some air-turbine handpieces showed the significant differences in total indicated run-out, however, the respective values were smaller than that at N=0 cycle. Accordingly, it can be considered that the ball bearing in the air-turbine handpieces is not affected significantly by autoclave. To further evaluate rotational performance, this study focused on the rotational vibration of the ball bearing components of the air-turbine, as measured by Fast Fourier Transform (FFT) analysis; the power spectra of frequency of the ball's revolution, frequency of the cage's rotation and frequency of the ball's rotation were comparatively investigated at N=0, 150 and 300 cycles, and the influence of autoclave was evaluated qualitatively. No abnormalities in the ball bearings were recognized.

  1. Catastrophic glacial multi-phase mass movements: a special type of glacial hazard

    Directory of Open Access Journals (Sweden)

    D. A. Petrakov

    2008-04-01

    Full Text Available Many glacier-related hazards are well typified and studied, but some events stand out from conventional classifications. The Kolka-Karmadon catastrophic event on 20 September 2002 in North Ossetia, North Caucasus, Russia is used as an example of a complex glacier failure exhibiting characteristics such as high mobility, long runout, ultrarapid movement and multiphase behaviour. We consider terminology protocol for glacier hazard classification and then, using the Kolka-Karmadon event and several other examples from around the world, we propose a new term for this family of events. Catastrophic glacier multi-phase mass movement (CGMM is described and further illustrated by eight major events from Russia, Georgia, Peru, Chile, and Canada. CGMM have a combination of specific features: extraordinary velocities and long-distance runout despite low path angle; progressive fluidisation along travel path; superelevation and run-up of the moving mass, air blast wave in the avalanche flow phase; entrainment of available materials in its path, and the repeated nature of the event. CGMM events may affect areas remote from glaciers which were previously considered as safe.

  2. Creep behavior in interlaminar shear of a Hi-NicalonTM/ SiC-B4C composite at 1200∘C in air and in steam

    Directory of Open Access Journals (Sweden)

    Ruggles-Wrenn Marina

    2015-01-01

    Full Text Available Creep behavior in interlaminar shear of a non-oxide ceramic composite with a multilayered matrix was investigated at 1200∘C in laboratory air and in steam environment. The composite was produced via chemical vapor infiltration (CVI. The composite had an oxidation inhibited matrix, which consisted of alternating layers of silicon carbide and boron carbide and was reinforced with laminated Hi-NicalonTM fibers woven in a five-harness-satin weave. Fiber preforms had pyrolytic carbon fiber coating with boron carbon overlay applied. The interlaminar shear properties were measured. The creep behavior was examined for interlaminar shear stresses in the 16–22 MPa range. Primary and secondary creep regimes were observed in all tests conducted in air and in steam. In air and in steam, creep run-out defined as 100 h at creep stress was achieved at 16 MPa. Similar creep strains were accumulated in air and in steam. Furthermore, creep strain rates and creep lifetimes were only moderately affected by the presence of steam. The retained properties of all specimens that achieved run-out were characterized. Composite microstructure, as well as damage and failure mechanisms were investigated. The tested specimens were also examined using electron probe microanalysis (EPMA with wavelength dispersive spectroscopy (WDS. Analysis of the fracture surfaces revealed significant surface oxidation, but only trace amounts of boron and carbon. Cross sectional analysis showed increasing boron concentration in the specimen interior.

  3. Consequence assessment of large rock slope failures in Norway

    Science.gov (United States)

    Oppikofer, Thierry; Hermanns, Reginald L.; Horton, Pascal; Sandøy, Gro; Roberts, Nicholas J.; Jaboyedoff, Michel; Böhme, Martina; Yugsi Molina, Freddy X.

    2014-05-01

    Steep glacially carved valleys and fjords in Norway are prone to many landslide types, including large rockslides, rockfalls, and debris flows. Large rockslides and their secondary effects (rockslide-triggered displacement waves, inundation behind landslide dams and outburst floods from failure of landslide dams) pose a significant hazard to the population living in the valleys and along the fjords shoreline. The Geological Survey of Norway performs systematic mapping of unstable rock slopes in Norway and has detected more than 230 unstable slopes with significant postglacial deformation. This large number necessitates prioritisation of follow-up activities, such as more detailed investigations, periodic displacement measurements, continuous monitoring and early-warning systems. Prioritisation is achieved through a hazard and risk classification system, which has been developed by a panel of international and Norwegian experts (www.ngu.no/en-gb/hm/Publications/Reports/2012/2012-029). The risk classification system combines a qualitative hazard assessment with a consequences assessment focusing on potential life losses. The hazard assessment is based on a series of nine geomorphological, engineering geological and structural criteria, as well as displacement rates, past events and other signs of activity. We present a method for consequence assessment comprising four main steps: 1. computation of the volume of the unstable rock slope; 2. run-out assessment based on the volume-dependent angle of reach (Fahrböschung) or detailed numerical run-out modelling; 3. assessment of possible displacement wave propagation and run-up based on empirical relations or modelling in 2D or 3D; and 4. estimation of the number of persons exposed to rock avalanches or displacement waves. Volume computation of an unstable rock slope is based on the sloping local base level technique, which uses a digital elevation model to create a second-order curved surface between the mapped extent of

  4. 复合材料加筋板长桁终止端设计与分析%Design and Analysis of Laminated Stiffened Composite Panels with Stringer Terminations

    Institute of Scientific and Technical Information of China (English)

    刘婷; 周凯华; 阴悦; 陈普会

    2013-01-01

    In an aircraft structure,it is often necessary to runout some of the stiffeners to satisfy detailed design requirements.Depending on the structural design,stiffeners for a wing structure may terminate at a chord-wise splice,at the forward or rear spar,at a rib,or at a structural discontinuity such as an access hole.Under in-plane loads,skin/stringer interfaces at run-out tips are vulnerable areas due to stiffness discontinuities and load-path centricities.In order to postpone the interface crack initiation and increase the failure load,stiffener webs are tapered near the termination,and then the portions of the skins lying below the run-out tip are thickened locally.The results of a parametric study examining these two types of design of laminated stiffened composite panels with stringer terminations are presented.The results indicate that local reinforcement on the skin can significantly increase the initial disbond load.%由于设计要求或设计限制条件,壁板的长桁常常在翼肋或机身框附近、机翼的前后梁附近及机翼与机身的开口附近、机翼的油箱附近等部位终止.在面内载荷作用下,截面形状突变和传载路径偏移都会造成端头处的应力集中,极易引起缘条/蒙皮界面的脱胶.为了延缓长桁末端的缘条/蒙皮界面的起裂,提高长桁终止端结构的失效载荷,采用经试验验证的数值方法,对长桁末端腹板斜削设计及长桁末端蒙皮增厚设计进行了研究.结果表明,蒙皮增厚设计可以明显提高结构的起裂载荷.

  5. Procedure for assessing the performance of a rockfall fragmentation model

    Science.gov (United States)

    Matas, Gerard; Lantada, Nieves; Corominas, Jordi; Gili, Josep Antoni; Ruiz-Carulla, Roger; Prades, Albert

    2017-04-01

    A Rockfall is a mass instability process frequently observed in road cuts, open pit mines and quarries, steep slopes and cliffs. It is frequently observed that the detached rock mass becomes fragmented when it impacts with the slope surface. The consideration of the fragmentation of the rockfall mass is critical for the calculation of block's trajectories and their impact energies, to further assess their potential to cause damage and design adequate preventive structures. We present here the performance of the RockGIS model. It is a GIS-Based tool that simulates stochastically the fragmentation of the rockfalls, based on a lumped mass approach. In RockGIS, the fragmentation initiates by the disaggregation of the detached rock mass through the pre-existing discontinuities just before the impact with the ground. An energy threshold is defined in order to determine whether the impacting blocks break or not. The distribution of the initial mass between a set of newly generated rock fragments is carried out stochastically following a power law. The trajectories of the new rock fragments are distributed within a cone. The model requires the calibration of both the runout of the resultant blocks and the spatial distribution of the volumes of fragments generated by breakage during their propagation. As this is a coupled process which is controlled by several parameters, a set of performance criteria to be met by the simulation have been defined. The criteria includes: position of the centre of gravity of the whole block distribution, histogram of the runout of the blocks, extent and boundaries of the young debris cover over the slope surface, lateral dispersion of trajectories, total number of blocks generated after fragmentation, volume distribution of the generated fragments, the number of blocks and volume passages past a reference line and the maximum runout distance Since the number of parameters to fit increases significantly when considering fragmentation, the

  6. Optimization of massive countermeasure design in complex rockfall settings

    Science.gov (United States)

    Agliardi, Federico; Crosta, Giovanni B.

    2015-04-01

    Rockfall protection is a major need in areas impended by subvertical rockwalls with complex 3D morphology and little or no talus to provide natural rockfall attenuation. The design of massive embankments, usually required to ensure such protection, is particularly difficult in complex rockfall settings, due to: widespread occurrence of rockfall sources; difficult characterization of size distribution and location of unstable volumes; variability of failure mechanisms; spatial scattering of rockfall trajectories; high expected kinetic energies. Moreover, rockwalls in complex lithological and structural settings are often prone to mass falls related to rock mass sector collapses. All these issues may hamper a safe application of classic embankment analysis approaches, using empirical rules or 2D-based height/energy statistics, and point to the need of integrated analyses of rock slope instability and rockfall runout in 3D. We explore the potential of combining advanced rock mass characterisation techniques and 3D rockfall modelling to support challenging countermeasure design at a site near Lecco (Southern Alps, Italy). Here subvertical cliffs up to 600 m high impend on a narrow (flat land along the Como Lake shore. Rock is thickly bedded limestone (Dolomia Principale Fm) involved in a ENE-trending, S-verging kilometre-scale anticline fold. The spatial variability of bedding attitude and fracture intensity is strongly controlled by the geological structure, with individual block sizes varying in the range 0.2-15 m3. This results in spatially variable rockfall susceptibility and mechanisms, from single block falls to mass falls. Several rockfall events occurred between 1981 and 2010 motivated the design of slope benching and a massive embankment. To support reliable design verification and optimization we performed a 3D assessment of both rock slope instability and rockfall runout. We characterised fracture patterns and rock mass quality associated to different

  7. Viewing inside Pyroclastic Flows - Large-scale Experiments on hot pyroclast-gas mixture flows

    Science.gov (United States)

    Breard, E. C.; Lube, G.; Cronin, S. J.; Jones, J.

    2014-12-01

    Pyroclastic density currents are the largest threat from volcanoes. Direct observations of natural flows are persistently prevented because of their violence and remain limited to broad estimates of bulk flow behaviour. The Pyroclastic Flow Generator - a large-scale experimental facility to synthesize hot gas-particle mixture flows scaled to pyroclastic flows and surges - allows investigating the physical processes behind PDC behaviour in safety. The ability to simulate natural eruption conditions and to view and measure inside the hot flows allows deriving validation and calibration data sets for existing numerical models, and to improve the constitutive relationships necessary for their effective use as powerful tools in hazard assessment. We here report on a systematic series of large-scale experiments on up to 30 ms-1 fast, 2-4.5 m thick, 20-35 m long flows of natural pyroclastic material and gas. We will show high-speed movies and non-invasive sensor data that detail the internal structure of the analogue pyroclastic flows. The experimental PDCs are synthesized by the controlled 'eruption column collapse' of variably diluted suspensions into an instrumented channel. Experiments show four flow phases: mixture acceleration and dilution during free fall; impact and lateral blasting; PDC runout; and co-ignimbrite cloud formation. The fully turbulent flows reach Reynolds number up to 107 and depositional facies similar to natural deposits. In the PDC runout phase, the shear flows develop a four-partite structure from top to base: a fully turbulent, strongly density-stratified ash cloud with average particle concentrations <<1vol%; a transient, turbulent dense suspension region with particle concentrations between 1 and 10 vol%; a non-turbulent, aerated and highly mobile dense underflows with particle concentrations between 40 and 50 vol%; and a vertically aggrading bed of static material. We characterise these regions and the exchanges of energy and momentum

  8. Landslide Mobility and Hazards: A Geophysical Overview of the Oso Disaster

    Science.gov (United States)

    Iverson, R. M.; George, D. L.; Allstadt, K.; Godt, J.; Reid, M. E.; Vallance, J. W.; Schilling, S. P.; Cannon, C.; Magirl, C. S.; Collins, B. D.; Baum, R. L.; Coe, J. A.; Schulz, W. H.; Bower, J. B.

    2014-12-01

    Some landslides move slowly or intermittently downslope, whereas others accelerate catastrophically and run out long distances across flat or gently sloping terrain. Seldom does landsliding of one type transition abruptly into the other, however, and seldom are the consequences more severe than at a site near Oso, Washington, where more than 40 fatalities resulted from a high-speed, long-runout landslide on 22 March 2014. Our interpretations of seismic data inversions and eyewitness accounts indicate that the Oso event began gradually, with remobilization of old landslide deposits that were unusually wet due to months of exceptional precipitation. For about 50 s, relatively slow downslope motion of these deposits withdrew support from a bluff above them, and then the bluff collapsed abruptly. This collapse radiated strong broadband seismic energy and rapidly loaded the old landslide material downslope. We infer that this rapid loading of previously dilated landslide debris caused contractive deformation, widespread liquefaction, and runaway acceleration. The resulting debris avalanche flow (DAF) had a volume of 8 ×106 m3and a fahrböschung (H/L ratio) of 0.106, making it exceptionally mobile for a landslide of its size. The leading edge of the Oso DAF may have gained mobility by entraining water as it displaced the adjacent Stillaguamish River and by liquefying wet floodplain sediments as it overran them, and it formed distal deposits that resembled those of many wood-freighted debris flows. The transition from relatively slow landslide motion (which had occurred intermittently for decades at the Oso site) to high-speed motion and long runout appears to have been very sensitive to contingencies. Our simulations of the Oso event using a new numerical model (D-Claw) show that small differences in water-saturated porosity (n) were sufficient to cause divergent landslide behaviors. In a case with n = 0.38, D-Claw predicts runaway liquefaction and high-speed runout

  9. The application of numerical debris flow modelling for the generation of physical vulnerability curves

    Directory of Open Access Journals (Sweden)

    B. Quan Luna

    2011-07-01

    Full Text Available For a quantitative assessment of debris flow risk, it is essential to consider not only the hazardous process itself but also to perform an analysis of its consequences. This should include the estimation of the expected monetary losses as the product of the hazard with a given magnitude and the vulnerability of the elements exposed. A quantifiable integrated approach of both hazard and vulnerability is becoming a required practice in risk reduction management. This study aims at developing physical vulnerability curves for debris flows through the use of a dynamic run-out model. Dynamic run-out models for debris flows are able to calculate physical outputs (extension, depths, velocities, impact pressures and to determine the zones where the elements at risk could suffer an impact. These results can then be applied to consequence analyses and risk calculations. On 13 July 2008, after more than two days of intense rainfall, several debris and mud flows were released in the central part of the Valtellina Valley (Lombardy Region, Northern Italy. One of the largest debris flows events occurred in a village called Selvetta. The debris flow event was reconstructed after extensive field work and interviews with local inhabitants and civil protection teams. The Selvetta event was modelled with the FLO-2D program, an Eulerian formulation with a finite differences numerical scheme that requires the specification of an input hydrograph. The internal stresses are isotropic and the basal shear stresses are calculated using a quadratic model. The behaviour and run-out of the flow was reconstructed. The significance of calculated values of the flow depth, velocity, and pressure were investigated in terms of the resulting damage to the affected buildings. The physical damage was quantified for each affected structure within the context of physical vulnerability, which was calculated as the ratio between the monetary loss and the reconstruction value. Three

  10. Role of Clay Minerals in Long-Distance Transport of Landslides in Valles Marineris, Mars

    Science.gov (United States)

    Watkins, J.; Ehlmann, B. L.; Yin, A.

    2014-12-01

    Long-runout (> 50 km) subaerial landslides are rare on Earth, but are common features episodically shaping Mars' Valles Marineris (VM) trough system over the past 3.5 billion years. They display two end-member morphologies: a thick-skinned inner zone, characterized by fault-bounded, rotated blocks near their source region, and a thin-skinned, exceptionally long-runout outer zone, characterized by thin sheets spreading over 10s of km across the trough floor. Four decades of studies on the latter have resulted in two main competing hypotheses to explain their long-distance transport: (1) movement of landslides over layers of trapped air or soft materials containing ice or snow, enabling basal lubrication, and (2) fluidization of landslide materials with or without the presence of water and volatiles. To address this issue, we examine the mineralogic composition of landslides across VM using Compact Reconnaissance Imaging Spectrometer for Mars (CRISM) near-infrared spectral data analysis coupled with detailed geologic mapping and morphometric analysis of satellite images. Our survey reveals a general correlation between transport distance, significant lateral spreading, and the presence of hydrated silicates among VM landslides. Given that smectite clay absorbs water into its layered crystal structure and can reduce the friction coefficient by a factor of three v. that of dry rocks, these results suggest that hydrated silicates played a decisive role in facilitating long-runout landslide transport in VM. We propose that, concurrent with downslope failure and sliding of broken trough-wall rock, frontal landslide masses overrode and entrained hydrated-silicate-bearing trough-floor deposits, lubricating the basal sliding zones and permitting the landslide outer zones to spread laterally while moving forward over the low-friction surface. The key participation of hydrated silicates in episodic, sustained landslide activity throughout the canyon implies that clay minerals

  11. Modelling submarine pyroclastic flows at the Soufrière Hills volcano, Montserrat

    Science.gov (United States)

    Hogg, A. J.; Goater, A.

    2011-12-01

    Submarine sedimentary flows are notoriously difficult to observe directly and interpreting their deposits to gain insight to the parent flows can be problematic. Pyroclastic flows from the Soufrière Hills volcano, Montserrat, which entered the ocean and deposited particles over the sea bed are a notable exception. In this case, from monitoring of the volcano, the mass of particulate released and the duration of the flow can be estimated accurately. Furthermore research cruises have imaged, cored the ocean bed and measured the distribution and composition of the deposit left by these flows over much of their runout. These observations therefore form a unique dataset in which both source conditions and final deposit are relatively well constrained. Mathematically modelling long runout sedimentary flows can also present several difficulties. Over these length and time scales, it is not feasible to simulate directly all of the fluid and particulate motions and so reduced models have been developed to capture the dominant processes and features of the flows. These have often been calibrated by laboratory scale experiments - but now with this data from the Soufrière Hills volcano, it is possible to compare model predictions with a natural scale event. Our model is based upon a shallow layer formulation, assuming hydrostatic balance in the vertical to leading order. The downslope motion of the sediment-laden fluid is driven by gravitational forces, associated with the density difference between the intruding and surrounding fluid. Particles settle out of the current to the underlying boundary, reducing the density difference, slowing the motion and forming the deposit. We develop a model that expresses conservation of fluid and particulate mass and a balance of streamwise momentum. This system of equations is integrated numerically to reveal the temporal and spatial evolution and asymptotic methods are used to reveal the dynamical controls on the runout. The theoretical

  12. Tsunami source model the 2011 Tohoku earthquake inferred from tsunami waveforms and coastal inundation heights

    Science.gov (United States)

    Stark, C. P.; Ekstrom, G.; Hibert, C.; Allen, J.

    2011-12-01

    Each year, a half-dozen or more kilometer-scale landslides strike mountain regions around the world. Each involves the acceleration and deceleration of millions of tons of debris at bulk rates of 1-3m/s^2, generating peak bulk-averaged forces well in excess of 10GN and exciting seismic waves whose long-period components are detectable at distances exceeding 1000km. We have studied around 40 such teleseismogenic (but not earthquake-triggered) landslides for the period 1980-2013, focusing mainly on inverting the long-period waveforms to infer time-series of landslide dynamical properties (the landslide force history or LFH; [1]), and recently extending our analysis to consider high-frequency seismicity recorded for well-instrumented events. It is now feasible to detect, measure and roughly geolocate >50GN, Msw>4.7 landslide events within a few hours of their occurrence, even if the landslides strike in very remote areas. Each rapid LFH inversion generates a good estimate of the runout geometry, which, for remote events, turns out to be very useful when trying to confirm and precisely locate the landslide occurrence in satellite imagery. With the advent of Landsat 8 it is now feasible to make such a confirmation within a week or so, weather permitting. A recent example is the rapid detection of a ~40Mt landslide in the Wrangell Mountains of Alaska that struck on 2013-07-25: the event was detected and roughly located with a few hours; within a few days, an LFH inversion gave its scale and runout path; the inversion and correlative short-period waveform analysis generated a sharper estimate for its location; a Landsat 8 image over the area was acquired within 8 days, and the new landslide scar was spotted shortly thereafter. This event extends our catalog of landslide source inversions and corroborates our general conclusions from this work, which are: (i) the glaciated mountains of Alaska, notably the St Elias Range and its neighbors, are the most catastrophic

  13. The Vaigat Rock Avalanche Laboratory, west-central Greenland

    Science.gov (United States)

    Dunning, S.; Rosser, N. J.; Szczucinski, W.; Norman, E. C.; Benjamin, J.; Strzelecki, M.; Long, A. J.; Drewniak, M.

    2013-12-01

    Rock avalanches have unusually high mobility and pose both an immediate hazard, but also produce far-field impacts associated with dam breach, glacier collapse and where they run-out into water, tsunami. Such secondary hazards can often pose higher risks than the original landslide. The prediction of future threats posed by potential rock avalanches is heavily reliant upon understanding of the physics derived from an interpretation of deposits left by previous events, yet drawing comparisons between multiple events is normally challenging as interactions with complex mountainous terrain makes deposits from each event unique. As such numerical models and the interpretation of the underlying physics which govern landslide mobility is commonly case-specific and poorly suited to extrapolation beyond the single events the model is tuned to. Here we present a high-resolution LiDAR and hyperspectral dataset captured across a unique cluster of large rock avalanche source areas and deposits in the Vaigat straight, west central Greenland. Vaigat offers the unprecedented opportunity to model a sample of > 15 rock avalanches of various age sourced from an 80 km coastal escarpment. At Vaigat many of the key variables (topography, geology, post-glacial history) are held constant across all landslides providing the chance to investigate the variations in dynamics and emplacement style related to variable landslide volume, drop-heights, and thinning/spreading over relatively simple, unrestricted run-out zones both onto land and into water. Our data suggest that this region represents excellent preservation of landslide deposits, and hence is well suited to calibrate numerical models of run out dynamics. We use this data to aid the interpretation of deposit morphology, structure lithology and run-out characteristics in more complex settings. Uniquely, we are also able to calibrate our models using a far-field dataset of well-preserved tsunami run-up deposits, resulting from the 21

  14. Untangling spider silk evolution with spidroin terminal domains

    Directory of Open Access Journals (Sweden)

    Garb Jessica E

    2010-08-01

    Full Text Available Abstract Background Spidroins are a unique family of large, structural proteins that make up the bulk of spider silk fibers. Due to the highly variable nature of their repetitive sequences, spidroin evolutionary relationships have principally been determined from their non-repetitive carboxy (C-terminal domains, though they offer limited character data. The few known spidroin amino (N-terminal domains have been difficult to obtain, but potentially contain critical phylogenetic information for reconstructing the diversification of spider silks. Here we used silk gland expression data (ESTs from highly divergent species to evaluate the functional significance and phylogenetic utility of spidroin N-terminal domains. Results We report 11 additional spidroin N-termini found by sequencing ~1,900 silk gland cDNAs from nine spider species that shared a common ancestor > 240 million years ago. In contrast to their hyper-variable repetitive regions, spidroin N-terminal domains have retained striking similarities in sequence identity, predicted secondary structure, and hydrophobicity. Through separate and combined phylogenetic analyses of N-terminal domains and their corresponding C-termini, we find that combined analysis produces the most resolved trees and that N-termini contribute more support and less conflict than the C-termini. These analyses show that paralogs largely group by silk gland type, except for the major ampullate spidroins. Moreover, spidroin structural motifs associated with superior tensile strength arose early in the history of this gene family, whereas a motif conferring greater extensibility convergently evolved in two distantly related paralogs. Conclusions A non-repetitive N-terminal domain appears to be a universal attribute of spidroin proteins, likely retained from the origin of spider silk production. Since this time, spidroin N-termini have maintained several features, consistent with this domain playing a key role in silk

  15. On the characteristics of landslide tsunamis.

    Science.gov (United States)

    Løvholt, F; Pedersen, G; Harbitz, C B; Glimsdal, S; Kim, J

    2015-10-28

    This review presents modelling techniques and processes that govern landslide tsunami generation, with emphasis on tsunamis induced by fully submerged landslides. The analysis focuses on a set of representative examples in simplified geometries demonstrating the main kinematic landslide parameters influencing initial tsunami amplitudes and wavelengths. Scaling relations from laboratory experiments for subaerial landslide tsunamis are also briefly reviewed. It is found that the landslide acceleration determines the initial tsunami elevation for translational landslides, while the landslide velocity is more important for impulsive events such as rapid slumps and subaerial landslides. Retrogressive effects stretch the tsunami, and in certain cases produce enlarged amplitudes due to positive interference. In an example involving a deformable landslide, it is found that the landslide deformation has only a weak influence on tsunamigenesis. However, more research is needed to determine how landslide flow processes that involve strong deformation and long run-out determine tsunami generation. © 2015 The Authors.

  16. Measuring method of outer raceway position accuracy for squirrel cage elastic support ball bearing%鼠笼弹支球轴承外圈沟位置精度的测量方法

    Institute of Scientific and Technical Information of China (English)

    孙怀全; 刘新强; 刘红莉

    2015-01-01

    鼠笼弹支球轴承外圈结构特殊,用常规的测量方法无法实现沟道位置尺寸及沟道中心对基准端面跳动的测量。通过实践探索,总结出新的测量方法,保证了轴承质量。%Because of the special structure in outer ring of squirrel cage elastic support ball bearing, it wass dififcult to measure the raceway position dimension and the runout of raceway center relative to reference plane with routine method.Through practical exploration, the improved measuring method was developed and the quality of bearing was guaranteed.

  17. Rifampicin resistant initiation of chromosome replication from oriC in ihf mutants

    DEFF Research Database (Denmark)

    von Freiesleben, Ulrik; Rasmussen, Knud V.; Atlung, Tove

    2000-01-01

    IHF (integration host factor) mutants exhibit asynchronous initiation of chromosome replication from oriC as determined from flow cytometric analysis of cultures where RNA synthesis was inhibited with rifampicin. However, the run-out kinetics of chromosome replication in ihf mutants shows...... that they continue to produce oriCs for some time in the absence of RNA synthesis resulting in a twofold increase in the oriC per mass ratio. An ihf dnaA double mutant did not exhibit this continued increase of the oriC per mass ratio. This indicates that ihf mutants can initiate replication from ori......C in a rifampicin-resistant initiation mode but requires fully functional DnaA protein. The origin per mass ratio, determined by a quantitative Southern blotting technique, showed that the ihf mutants had an origin per mass ratio that was 60% of the wild type although it had a normal DnaA protein concentration...

  18. Dynamical weakening of pyroclastic flows by mechanical vibrations

    Science.gov (United States)

    Valverde, Jose Manuel; Soria-Hoyo, Carlos; Roche, Olivier

    2017-06-01

    Dynamical weakening of dense granular flows plays a critical role on diverse geological events such as seismic faulting and landslides. A common feature of these processes is the development of fluid-solid relative flows that could lead to fluidization by hydrodynamic viscous stresses. Volcanic ash landslides (pyroclastic flows) are characterized by their high mobility often attributed to fluidization of the usually fine and/or low-density particles by their interaction with the entrapped gas. However, the physical mechanism that might drive sustained fluidization of these dense granular flows over extraordinarily long runout distances is elusive. The behavior of volcanic ash in a slowly rotating drum subjected to mechanical vibrations shown in this work suggests that fluid-particle relative oscillations in dense granular flows present in volcanic eruption events can promote pore gas pressure at reduced shear rates as to sustain fluidization.

  19. Final prototype of magnetically suspended flywheel energy storage system

    Science.gov (United States)

    Anand, D. K.; Kirk, J. A.; Zmood, R. B.; Pang, D.; Lashley, C.

    1991-01-01

    A prototype of a 500 Wh magnetically suspended flywheel energy storage system was designed, built, and tested. The authors present the work done and include the following: (1) a final design of the magnetic bearing, control system, and motor/generator, (2) construction of a prototype system consisting of the magnetic bearing stack, flywheel, motor, container, and display module, and (3) experimental results for the magnetic bearings, motor, and the entire system. The successful completion of the prototype system has achieved: (1) manufacture of tight tolerance bearings, (2) stability and spin above the first critical frequency, (3) use of inside sensors to eliminate runout problems, and (4) integration of the motor and magnetic bearings.

  20. Fatigue behavior of two alloys for Space Shuttle applications. [Inconel 903 and 718 for main engine

    Science.gov (United States)

    Adsit, N. R.; Block, S. J.

    1978-01-01

    Two superalloys used extensively in the Space Shuttle main engine are Incoloy 903 and Inconel 718. The fatigue behavior of the two alloys under varying conditions is considered. Three heats of Incoloy 903 and two of Inconel 718 were used in the study. Material was tested in several conditions, including mill polish, longitudinal mill polish, transverse mill polish, chemically milled, chemically milled plus shotpeened on one side and on both sides, gas tungsten arc welded, and electron beam welded. Both round and flat tensile specimens were tested in universal test machines. It was found that surface condition influences test results. Transverse scratches resulting from polishing and rougher surfaces lower the stress at runout in relation to that obtained on longitudinally polished and/or smooth-surfaced specimens.

  1. The Effect of Structural Quality on Fatigue Life in 319 Aluminum Alloy Castings

    Science.gov (United States)

    Özdeş, Hüseyin; Tiryakioğlu, Murat

    2016-12-01

    Tensile and fatigue life data for 319 aluminum alloy from seventeen datasets reported in four independent studies from the literature have been reanalyzed. Analysis of fatigue life data involved mean stress correction for different R ratios used in fatigue testing, inclusion of survival (runout) data along with failure data, as well as volumetric correction for Weibull distributions for different specimen sizes used in these studies. Tensile data have been transformed into the structural quality index, Q T, which is used as a measure of the structural quality of castings. A distinct relationship has been observed between the expected fatigue life and mean quality index. Moreover, fatigue strengths at 104 and 106 cycles have been found increase with quality index, providing further evidence about the relationship observed between structural quality and fatigue performance. Empirical equations between Basquin parameters and structural quality index have been developed. The use of the comprehensive methodology to estimate fatigue life is demonstrated with an example.

  2. Oil Coking Prevention Using Electric Water Pump for Turbo-Charge Spark-Ignition Engines

    Directory of Open Access Journals (Sweden)

    Han-Ching Lin

    2014-01-01

    Full Text Available Turbocharger has been widely implemented for internal combustion engine to increase an engine's power output and reduce fuel consumption. However, its operating temperature would rise to 340°C when engine stalls. This higher temperature may results in bearing wear, run-out, and stick, due to oil coking and insufficient lubrication. In order to overcome these problems, this paper employs Electric Water Pump (EWP to supply cool liquid to turbocharger actively when the engine stalls. The system layout, operating timing, and duration of EWP are investigated for obtaining optimal performance. The primarily experimental results show that the proposed layout and control strategy have a lower temperature of 100°C than the conventional temperature 225°C.

  3. Crater-related flow features on Ceres - Implications for cryovolcanism

    Science.gov (United States)

    Jaumann, R.; Krohn, K.; Stephan, K.; Otto, K. A.; Schmedemann, N.; Wagner, R. J.; Matz, K. D.; Tosi, F.; Zambon, F.; von der Gathen, I.; Schulzeck, F.; Buczkowski, D.; Hiesinger, H.; McSween, H. Y., Jr.; Pieters, C. M.; Preusker, F.; Roatsch, T.; Raymond, C. A.; Russell, C. T.; Williams, D. A.

    2016-12-01

    Some craters on Ceres show post-impact modifications, like the deposition of extended plains laced with pits, lobate flows, and ponded material [1]. We found those features on craters with a bluish spectral signature, such as Haulani, Ikapati, Occator and Kupalo. Lobate flows of Haulani and Kupalo originating from the crest of the central ridge [1,2] partly overwhelming the mass wasting deposits from the rim, indicating possible post-impact resurfacing processes [3,4]. The drop height-to-runout length ratio of several flow features of the four craters reveals a coefficient of friction of Castillo-Rogez J.C. and McCord T.B., 2010, Icarus 203, 443-459. [6] Fu et al., 2015, AGU #P23D-02. [7] De Sanctis M.C., et al., 2015, Nature 528, 241-244. [8] Neumann W., et al., 2016, LPSC #2307. [9] Schmedemann N., et al., 2016, LPSC # 2236.

  4. The Effect of Structural Quality on Fatigue Life in 319 Aluminum Alloy Castings

    Science.gov (United States)

    Özdeş, Hüseyin; Tiryakioğlu, Murat

    2017-02-01

    Tensile and fatigue life data for 319 aluminum alloy from seventeen datasets reported in four independent studies from the literature have been reanalyzed. Analysis of fatigue life data involved mean stress correction for different R ratios used in fatigue testing, inclusion of survival (runout) data along with failure data, as well as volumetric correction for Weibull distributions for different specimen sizes used in these studies. Tensile data have been transformed into the structural quality index, Q T, which is used as a measure of the structural quality of castings. A distinct relationship has been observed between the expected fatigue life and mean quality index. Moreover, fatigue strengths at 104 and 106 cycles have been found increase with quality index, providing further evidence about the relationship observed between structural quality and fatigue performance. Empirical equations between Basquin parameters and structural quality index have been developed. The use of the comprehensive methodology to estimate fatigue life is demonstrated with an example.

  5. Fasteners 5 basic standards

    CERN Document Server

    2011-01-01

    This 3rd edition of DIN Handbook 193 contains 38 fundamental standards on fasteners, covering such areas as countersinks and counterbores, widths across flats, thread run-outs and thread undercuts, bolt and screw ends, stud ends and tapped holes for compression couplings, driving features, tolerances for screw threads and nomenclature. New to this compilation are DIN 34824 dealing with 12 point sockets for bolts and screws and DIN EN ISO 15065 which reflects current practice in Europe with regard to countersinks for countersunk head screws. Also included for the first time is DIN EN ISO 225 "Fasteners - Bolts, screws, studs and nuts - Symbols and descriptions of dimensions" which, together with DIN ISO 1891, now also incorporates terminology in Chinese, Japanese and Swedish. Four standards have been revised for this edition, among them DIN 918 Supplement 3 which provides information on the current status of European standardization relating to fasteners. DIN Handbook 193 is one of a series of six handbooks on...

  6. Preliminary safety analysis of Pb-Bi cooled 800 MWt modified CANDLE burn-up scheme based fast reactors

    Science.gov (United States)

    Su'ud, Zaki; Sekimoto, H.

    2014-09-01

    Pb-Bi Cooled fast reactors with modified CANDLE burn-up scheme with 10 regions and 10 years cycle length has been investigated from neutronic aspects. In this study the safety aspect of such reactors have been investigated and discussed. Several condition of unprotected loss of flow (ULOF) and unprotected rod run-out transient over power (UTOP) have been simulated and the results show that the reactors excellent safety performance. At 80 seconds after unprotected loss of flow condition, the core flow rate drop to about 25% of its initial flow and slowly move toward its natural circulation level. The maximum fuel temperature can be managed below 1000°C and the maximum cladding temperature can be managed below 700°C. The dominant reactivity feedback is radial core expansion and Doppler effect, followed by coolant density effect and fuel axial expansion effect.

  7. 3D modeling of the Buhi debris avalanche deposit of Iriga Volcano, Philippines by integrating shallow-seismic reflection and geological data

    Science.gov (United States)

    Minimo, Likha G.; Lagmay, Alfredo Mahar Francisco A.

    2016-06-01

    Numerical models for simulating volcanic debris avalanches commonly lack a critical initiation parameter, the source volume, which is difficult to estimate without data on the deposit thickness. This, in turn, limits how rheology can be characterized for simulating flow. Leapfrog Geo, a 3D geological modeling software, was used to integrate shallow-seismic reflection profiles with field and borehole data to determine the volume of the Buhi debris avalanche and the pre-collapse structure of Iriga Volcano. Volumes of the deposit calculated in this way are 34-71% larger than previous estimates. This technique may improve models of debris avalanches elsewhere in the world, and more precisely depict landslide runout and lateral extent, thus improving disaster prevention and mitigation for the many cities located near volcanoes.

  8. Surface topography of cylindrical gear wheels after smoothing in abrasive mass, honing and shot peening

    Energy Technology Data Exchange (ETDEWEB)

    Michalski, J; Pawlus, P [Rzeszow University of Technology, W Pola 2, 35-935 Rzeszow (Poland); Zelasko, W, E-mail: jmichals@prz.edu.pl [Technical School Complex at Lezajsk, Mickiewicza 67, 37-300 Lezajsk (Poland)

    2011-08-19

    The present paper presents the analysis of surface topography of gear teeth as the result of final machining processes. Teeth of multiple cylindrical gears shaped by grinding were smoothed in abrasive mass, honed or shot peened. The measurement of gears were made using coordinate measuring machine and 3D surface topography stylus instrument. The following deviations were studied; pitch deviation, total pitches deviations, variation of teeth thickness and deviation of gear radial run-out. Changes in teeth surface topography during machining process were determined. 3D surface topography parameters, surface directionality as well as areal autocorrelation and power spectral density functions were taken into consideration. As the results of the analysis, the best surface topography with regard to gear operational properties was recommended.

  9. Surface topography of cylindrical gear wheels after smoothing in abrasive mass, honing and shot peening

    Science.gov (United States)

    Michalski, J.; Pawlus, P.; Żelasko, W.

    2011-08-01

    The present paper presents the analysis of surface topography of gear teeth as the result of final machining processes. Teeth of multiple cylindrical gears shaped by grinding were smoothed in abrasive mass, honed or shot peened. The measurement of gears were made using coordinate measuring machine and 3D surface topography stylus instrument. The following deviations were studied; pitch deviation, total pitches deviations, variation of teeth thickness and deviation of gear radial run-out. Changes in teeth surface topography during machining process were determined. 3D surface topography parameters, surface directionality as well as areal autocorrelation and power spectral density functions were taken into consideration. As the results of the analysis, the best surface topography with regard to gear operational properties was recommended.

  10. Reevaluation of tsunami formation by debris avalanche at Augustine Volcano, Alaska

    Science.gov (United States)

    Waythomas, C.F.

    2000-01-01

    Debris avalanches entering the sea at Augustine Volcano, Alaska have been proposed as a mechanism for generating tsunamis. Historical accounts of the 1883 eruption of the volcano describe 6- to 9-meter-high waves that struck the coastline at English Bay (Nanwalek), Alaska about 80 kilometers east of Augustine Island. These accounts are often cited as proof that volcanigenic tsunamis from Augustine Volcano are significant hazards to the coastal zone of lower Cook Inlet. This claim is disputed because deposits of unequivocal tsunami origin are not evident at more than 50 sites along the lower Cook Inlet coastline where they might be preserved. Shallow water (Augustine Island, in the run-out zone for debris avalanches, limits the size of an avalanche-caused wave. If the two most recent debris avalanches, Burr Point (A.D. 1883) and West Island (Augustine Volcano appears minor, unless a very large debris avalanche occurs at high tide.

  11. Subaerial and subaqueous dynamics of coastal rockfalls

    Science.gov (United States)

    De Blasio, Fabio Vittorio; Mazzanti, Paolo

    2010-02-01

    In spite of the hazard represented by rockfalls in coastal areas, few investigators have studied the movement of rocks falling in water. This work describes a model for the propagations of coastal rockfalls, i.e., blocks detaching from a subaerial cliff, propagating initially in air, impacting against the water surface, and finally coming to rest in the water basin. Application of the model to two real cases in Italy shows a satisfactory agreement between the predicted rockfall run-out and the field data. Some scattering observed in the data is explained as the consequence of different heights of the source area. It is shown that largest boulders usually reach a longer distance. However, the schematic shape for blocks adopted in the model likely results in a much more regular behaviour compared to reality.

  12. Simple scaling of catastrophic landslide dynamics.

    Science.gov (United States)

    Ekström, Göran; Stark, Colin P

    2013-03-22

    Catastrophic landslides involve the acceleration and deceleration of millions of tons of rock and debris in response to the forces of gravity and dissipation. Their unpredictability and frequent location in remote areas have made observations of their dynamics rare. Through real-time detection and inverse modeling of teleseismic data, we show that landslide dynamics are primarily determined by the length scale of the source mass. When combined with geometric constraints from satellite imagery, the seismically determined landslide force histories yield estimates of landslide duration, momenta, potential energy loss, mass, and runout trajectory. Measurements of these dynamical properties for 29 teleseismogenic landslides are consistent with a simple acceleration model in which height drop and rupture depth scale with the length of the failing slope.

  13. Effect of Controlled Cooling After Hot Rolling on Mechanical Properties of Hot Rolled TRIP Steel

    Institute of Scientific and Technical Information of China (English)

    WU Di; LI Zhuang; L(U) Hui-sheng

    2008-01-01

    A three-step cooling pattern on the runout table (ROT) was conducted for the hot rolled TRIP steel. Microstructural evolution during thermomechanical controlled processing (TMCP) was investigated. Proeessing condition of controlled cooling on a ROT in the laboratory rolling mill was discussed. The results indicated that the microstructure containing polygonal ferrite, granular bainite and a significant amount of the stable retained austenite can be obtained through three-step cooling on the ROT after hot rolling. TMCP led to ferrite grain refinement. Controlled cooling after hot rolling resulted in the stability of the remaining austenite and a satisfactory TRIP effect. Excellent mechanical properties were obtained through TMCP for the hot rolled TRIP steel.

  14. Maximum speeds and alpha angles of flowing avalanches

    Science.gov (United States)

    McClung, David; Gauer, Peter

    2016-04-01

    um/√H0--; um/√S0- are greater than 2.0 and 1.3 respectively. In addition, to: um/√H0--; um/√S0--, we collected 105 companion values of the αangle for runout positions defined by tanα = H0/X0where X0is horizontal reach calculated from start position to stop position of the tip of the avalanches. The αangle is a very simple measure of runout introduced by Scheidegger (1973) for rock avalanches. McClung and Mears (1991) collected αangles from more than 500 paths with maximum runout estimated for return periods on the order of 100 years and the range of values was: 18o - 42owhich is close to that here: (20o - 45o). The results showed that runout increases(α decreases) with maximum speed but there is considerable scatter in the relationship. The Spearman rank correlation is -0.54 (p < 0.005).Rank correlations of α vs. um/√S0-;um/√H0- are - 0.44;.- 0.56 (both with p < 0.005

  15. The perfect ash-storm: large-scale Pyroclastic Density Current experiments reveal highly mobile, self-fluidising and air-cushioned flow transport regime

    Science.gov (United States)

    Lube, G.; Cronin, S. J.; Breard, E.; Valentine, G.; Bursik, M. I.; Hort, M. K.; Freundt, A.

    2013-12-01

    We report on the first systematic series of large-scale Pyroclastic Density Current (PDC) experiments using the New Zealand PDC Generator, a novel international research facility in Physical Volcanology recently commissioned at Massey University. Repeatable highly energetic and hot PDCs are synthesized by the controlled ';eruption column-collapse' of up to 3500 kg of homogenously aerated Taupo ignimbrite material from a 15 m-elevated hopper onto an instrumented inclined flume. At discharge rates between 250-1300 kg/s and low- to moderate gas injection rates (yielding initial solids concentration of 15-70 vol%) channelized gas-particle mixture flows life-scaled to dense PDCs can be generated. The flow fronts of the currents reach velocities of up to 9.5 m/s over their first 12 m of travel and rapidly develop strong vertical density stratification. The PDCs typically form a highly mobile, surge that also laterally escapes the flume boundaries. Depending on the PDC starting conditions underflows with 1-45 vol% solids concentration are formed, while the upper surge contains <<1 vol.% solids. A characteristic feature of the underflow is the occurrence of 'ignitive' front breakouts, producing jetted lobes that accelerate outward from the flow front, initially forming a lobe-cleft structure, followed by segregation downslope into multiple flow pulses. Depending on initial solids concentration and discharge rate, stratified, dune-bedded and inversely graded bedforms are created whose thicknesses are remarkably uniform along the medial to distal runout path characterising highly mobile flow runout. Along with high-speed video footage we present time-series data of basal arrays of load- and gas-pore pressure transducers to characterise the mobile dense underflows. Data shows that the PDCs are comprised of a turbulent coarse-grained and air-ingesting front with particle-solids concentrations of 1-5 vol%. The front shows a brief phase of negative pore pressure due to the

  16. Mobility of pyroclastic flows and surges at the Soufriere Hills Volcano, Montserrat

    Science.gov (United States)

    Calder, E.S.; Cole, P.D.; Dade, W.B.; Druitt, T.H.; Hoblitt, R.P.; Huppert, H.E.; Ritchie, L.; Sparks, R.S.J.; Young, S.R.

    1999-01-01

    The Soufriere Hills Volcano on Montserrat has produced avalanche-like pyroclastic flows formed by collapse of the unstable lava dome or explosive activity. Pyroclastic flows associated with dome collapse generate overlying dilute surges which detach from and travel beyond their parent flows. The largest surges partially transform by rapid sedimentation into dense secondary pyroclastic flows that pose significant hazards to distal areas. Different kinds of pyroclastic density currents display contrasting mobilities indicated by ratios of total height of fall H, run-out distance L, area inundated A and volume transported V. Dome-collapse flow mobilities (characterised by either L/H or A/V 2/3) resemble those of terrestrial and extraterrestrial cold-rockfalls (Dade and Huppert, 1998). In contrast, fountain-fed pumice flows and fine-grained, secondary pyroclastic flows travel slower but, for comparable initial volumes and heights, can inundate greater areas.

  17. Rockfall susceptibility map for Athinios port, Santorini Island, Greece

    Science.gov (United States)

    Antoniou, Andreas A.; Lekkas, Efthimios

    2010-05-01

    This article analyzes rockfall susceptibility in the steep caldera slopes upstream of Athinios port, Santorini Island, Greece. The study area is situated in the internal rim of a submarine caldera where the most important problem that is recorded is the frequent rockfalls that not only cause damages to roads and vehicles but also pose a threat to people that are transported or located on the port. As a result, a methodology which combines information relatively to surficial and engineering geology, geomorphological processes, and structural analysis was adopted. The methodology incorporates evenly a maximum runout map generated by means of reach probability of rock block analysis, using the empirical model of "reach angle". Additionally volumes of rockfall events categorized and presented through a map to assist the compilation of rockfall susceptibility map which allows us to identify areas and human activities exposed to these incidents and set up several protection meters.

  18. Use of terrestrial laser scanning for engineering geological applications on volcanic rock slopes - an example from Madeira island (Portugal)

    Science.gov (United States)

    Nguyen, H. T.; Fernandez-Steeger, T. M.; Wiatr, T.; Rodrigues, D.; Azzam, R.

    2011-03-01

    This study focuses on the adoption of a modern, widely-used Terrestrial Laser Scanner (TLS) application to investigate volcanic rock slopes in Ribeira de João Gomes valley (Funchal, Madeira island). The TLS data acquisition in May and December 2008 provided information for a characterization of the volcanic environment, detailed structural analysis and detection of potentially unstable rock masses on a slope. Using this information, it was possible to determine specific parameters for numerical rockfall simulations such as average block size, shape or potential sources. By including additional data, such as surface roughness, the results from numerical rockfall simulations allowed us to classify different hazardous areas based on run-out distances, frequency of impacts and related kinetic energy. Afterwards, a monitoring of hazardous areas can be performed in order to establish a rockfall inventory.

  19. Numerical analysis of submarine landslides using a smoothed particle hydrodynamics depth integral model

    Institute of Scientific and Technical Information of China (English)

    WANG Zhongtao; LI Xinzhong; LIU Peng; TAO Yanqi

    2016-01-01

    Submarine landslides can cause severe damage to marine engineering structures. Their sliding velocity and runout distance are two major parameters for quantifying and analyzing the risk of submarine landslides. Currently, commercial calculation programs such as BING have limitations in simulating underwater soil movements. All of these processes can be consistently simulated through a smoothed particle hydrodynamics (SPH) depth integrated model. The basis of the model is a control equation that was developed to take into account the effects of soil consolidation and erosion. In this work, the frictional rheological mode has been used to perform a simulation study of submarine landslides. Time-history curves of the sliding body’s velocity, height, and length under various conditions of water depth, slope gradient, contact friction coefficient, and erosion rate are compared; the maximum sliding distance and velocity are calculated; and patterns of variation are discussed. The findings of this study can provide a reference for disaster warnings and pipeline route selection.

  20. An investigation the effects of geometric tolerances on the natural frequencies of rotating shafts

    Directory of Open Access Journals (Sweden)

    Ali Akbar Ansarifard

    2015-04-01

    Full Text Available This paper presents the effects of geometric tolerances on the rotating shafts natural frequencies. Due to modeling the tolerances, a code is written in MATLAB 2013 software that produces deviated points. Deviated points are controlled by different geometric tolerances, including cylindricity, total run-out and coaxiality tolerances. Final surfaces and models passing through the points are created using SolidWorks 2013 software and finally modal analysis is carried out with the FE software. It is observed whatever the natural frequency is higher or the geometric tolerances are greater, the real and ideal shafts natural frequencies are more distant. Also difference percentage between ideal and real frequencies is investigated. The results show that the percentage value is approximately constant for every mode shapes.

  1. Catastrophic debris flows transformed from landslides in volcanic terrains : mobility, hazard assessment and mitigation strategies

    Science.gov (United States)

    Scott, Kevin M.; Macias, Jose Luis; Naranjo, Jose Antonio; Rodriguez, Sergio; McGeehin, John P.

    2001-01-01

    Communities in lowlands near volcanoes are vulnerable to significant volcanic flow hazards in addition to those associated directly with eruptions. The largest such risk is from debris flows beginning as volcanic landslides, with the potential to travel over 100 kilometers. Stratovolcanic edifices commonly are hydrothermal aquifers composed of unstable, altered rock forming steep slopes at high altitudes, and the terrain surrounding them is commonly mantled by readily mobilized, weathered airfall and ashflow deposits. We propose that volcano hazard assessments integrate the potential for unanticipated debris flows with, at active volcanoes, the greater but more predictable potential of magmatically triggered flows. This proposal reinforces the already powerful arguments for minimizing populations in potential flow pathways below both active and selected inactive volcanoes. It also addresses the potential for volcano flank collapse to occur with instability early in a magmatic episode, as well as the 'false-alarm problem'-the difficulty in evacuating the potential paths of these large mobile flows. Debris flows that transform from volcanic landslides, characterized by cohesive (muddy) deposits, create risk comparable to that of their syneruptive counterparts of snow and ice-melt origin, which yield noncohesive (granular) deposits, because: (1) Volcano collapses and the failures of airfall- and ashflow-mantled slopes commonly yield highly mobile debris flows as well as debris avalanches with limited runout potential. Runout potential of debris flows may increase several fold as their volumes enlarge beyond volcanoes through bulking (entrainment) of sediment. Through this mechanism, the runouts of even relatively small collapses at Cascade Range volcanoes, in the range of 0.1 to 0.2 cubic kilometers, can extend to populated lowlands. (2) Collapse is caused by a variety of triggers: tectonic and volcanic earthquakes, gravitational failure, hydrovolcanism, and

  2. Multi temporal LiDAR-DTMs as a tool for modelling a complex landslide: a case study in the Rotolon catchment (Eastern Italian Alps

    Directory of Open Access Journals (Sweden)

    G. Bossi

    2014-10-01

    Full Text Available The geomorphological change detection through the comparison of repeated topographic surveys is a recent approach that benefits greatly from the latest developments in topographical data acquisition techniques. Among them, airborne LiDAR makes the monitoring of geomorphological changes a more reliable and accurate approach for natural hazard and risk management. In this study, two LiDAR-DTMs (2 m resolution were acquired just before and after a complex 340 000 m3 landslide event (4 November 2010 that generated a debris flow in the channel of the Rotolon catchment (Eastern Italian Alps. The analysis of these data was used to set up the initial condition for the application of a dynamic model. The comparison between the pre- and post-event DTMs allowed to identify erosion and depositional areas and the volume of the landslide. The knowledge of the phenomenon dynamics was the base of a sound back-analysis of the event with the 3-D numerical model DAN3D. This particular code was selected for its capability to modify the rheology and the parameters of the moving mass during run-out, as actually observed along the path of the 2010 debris flow. Nowadays some portions of Mt. Rotolon flank are still moving and show signs of detachment. The same soil parameters used in the back-analysis model could be used to simulate the run-out for possible future landslides allowing to generate reliable risk scenarios useful for awareness of civil defense and strategy on emergency plans.

  3. A depth integrated model for dry geophysical granular flows

    Science.gov (United States)

    Rossi, Giulia; Armanini, Aronne

    2017-04-01

    Granular flows are rapid to very rapid flows, made up of dry sediment (rock and snow avalanches) or mixture of water and sediment (debris flows). They are among the most dangerous and destructive natural phenomena and the definition of run-out scenarios for risk assessment has received wide interest in the last decades. Nowadays there are many urbanized mountain areas affected by these phenomena, which cause several properties damages and loss of lives. The numerical simulation is a fundamental step to analyze these phenomena and define the runout scenarios. For this reason, a depth-integrated model is developed to analyze the case of dry granular flows, representative of snow avalanches or rock avalanches. The model consists of a two-phase mathematical description of the flow motion: it is similar to the solid transport equations but substantially different since there is no water in this case. A set of partial differential equations is obtained and written in the form of a hyperbolic system. The numerical solution is computed through a path-conservative SPH (Smoothed Particles Hydrodynamics) scheme, in the two dimensional case. Appropriate closure relations are necessary, with respect to the concentration C and the shear stress at the bed τ0. In first approximation, it is possible to derive a formulation for the two closure relations from appropriate rheological models (Bagnold theory and dense gas analogy). The model parameters are determined by means of laboratory tests on dry granular material and the effectiveness of the closure relation verified through a comparison with the experimental results. In particular, the experimental investigation aims to reproduce two case of study for dry granular material: the dam-break test problem and the stationary motion with changes in planimetry. The experiments are carried out in the Hydraulic Laboratory of the University of Trento, by means of channels with variable slope and variable shape. The mathematical model will

  4. Dynamics of the Bingham Canyon rock avalanches (Utah, USA) resolved from topographic, seismic, and infrasound data

    Science.gov (United States)

    Moore, Jeffrey R.; Pankow, Kristine L.; Ford, Sean R.; Koper, Keith D.; Hale, J. Mark; Aaron, Jordan; Larsen, Chris F.

    2017-03-01

    The 2013 Bingham Canyon Mine rock avalanches represent one of the largest cumulative landslide events in recorded U.S. history and provide a unique opportunity to test remote analysis techniques for landslide characterization. Here we combine aerial photogrammetry surveying, topographic reconstruction, numerical runout modeling, and analysis of broadband seismic and infrasound data to extract salient details of the dynamics and evolution of the multiphase landslide event. Our results reveal a cumulative intact rock source volume of 52 Mm3, which mobilized in two main rock avalanche phases separated by 1.5 h. We estimate that the first rock avalanche had 1.5-2 times greater volume than the second. Each failure initiated by sliding along a gently dipping (21°), highly persistent basal fault before transitioning to a rock avalanche and spilling into the inner pit. The trajectory and duration of the two rock avalanches were reconstructed using runout modeling and independent force history inversion of intermediate-period (10-50 s) seismic data. Intermediate- and shorter-period (1-50 s) seismic data were sensitive to intervals of mass redirection and constrained finer details of the individual slide dynamics. Back projecting short-period (0.2-1 s) seismic energy, we located the two rock avalanches within 2 and 4 km of the mine. Further analysis of infrasound and seismic data revealed that the cumulative event included an additional 11 smaller landslides (volumes 104-105 m3) and that a trailing signal following the second rock avalanche may result from an air-coupled Rayleigh wave. Our results demonstrate new and refined techniques for detailed remote characterization of the dynamics and evolution of large landslides.

  5. Catastrophic precipitation-triggered lahar at Casita volcano, Nicaragua: Occurrence, bulking and transformation

    Science.gov (United States)

    Scott, K.M.; Vallance, J.W.; Kerle, N.; Macias, J.L.; Strauch, W.; Devoli, G.

    2005-01-01

    A catastrophic lahar began on 30 October 1998, as hurricane precipitation triggered a small flank collapse of Casita volcano, a complex and probably dormant stratovolcano. The initial rockslide-debris avalanche evolved on the flank to yield a watery debris flood with a sediment concentration less than 60 per cent by volume at the base of the volcano. Within 2-5 km, however, the watery flow entrained (bulked) enough sediment to transform entirely to a debris flow. The debris flow, 6 km downstream and 1??2 km wide and 3 to 6 m deep, killed 2500 people, nearly the entire populations of the communities of El Porvenir and Rolando Rodriguez. These 'new towns' were developed in a prehistoric lahar pathway: at least three flows of similar size since 8330 14C years BP are documented by stratigraphy in the same 30-degree sector. Travel time between perception of the flow and destruction of the towns was only 2??5-3??0 minutes. The evolution of the flow wave occurred with hydraulic continuity and without pause or any extraordinary addition of water. The precipitation trigger of the Casita lahar emphasizes the nee d, in volcano hazard assessments, for including the potential for non-eruption-related collapse lahars with the more predictable potential of their syneruption analogues. The flow behaviour emphasizes that volcano collapses can yield not only volcanic debris avalanches with restricted runouts, but also mobile lahars that enlarge by bulking as they flow. Volumes and hence inundation areas of collapse-runout lahars can increase greatly beyond their sources: the volume of the Casita lahar bulked to at least 2??6 times the contributing volume of the flank collapse and 4??2 times that of the debris flood. At least 78 per cent of the debris flow matrix (sediment flow. Copyright c 2004 John Wiley & Sons, Ltd.

  6. Some influences of rock strength and strain rate on propagation of rock avalanches

    Science.gov (United States)

    Bowman, Elisabeth; Rait, Kim

    2016-04-01

    Rock avalanches are extreme and destructive mass movements in which large volumes of rock (typically >1 million cubic metres) travel at high speeds, covering large distances, and the occurrence of which is highly unpredictable. The "size effect" in rock avalanches, whereby those with larger volumes produce greater spreading efficiency (as defined by an increase in normalised runout) or lower farboschung angle (defined as the tangent of the ratio of fall height to runout length), is well known. Studies have shown that rock strength is a controlling factor in the mobility of rock avalanches - that is, mass movements involving lower strength rock are generally found to produce greater mobility as evidenced by the spread of deposits or low farboschung angle. However, there are conflicting ideas as to how and why this influence is manifested. This paper discusses different theories of rock comminution in light of numerical simulations of rock clasts undergoing normal and shear induced loading, experimental work on rock avalanche behaviour, and dynamic fracture mechanics. In doing so, we introduce the idea of thresholds of strain rate for the production of dynamic fragmentation (as opposed to pseudo-static clast crushing) that are based, inter alia, on static rock strength. To do this, we refer to data from physical models using rock analogue materials, field data on chalk cliff collapses, and field statistics from documented rock avalanches. The roles of normal and shear loading and loading rate within a rock avalanche are examined numerically using 3D Discrete Element Method models of rock clasts loaded to failure. Results may help to reconcile the observations that large rock avalanches in stronger materials tend not to fragment as much as those in weaker materials and also possess lower mobility, while small cliff collapses (typically > 1000 cubic metres) in weak chalk can exhibit rock avalanche-like behaviour at much smaller volumes.

  7. Causes and mobility of large volcanic landslides: application to Tenerife, Canary Islands

    Science.gov (United States)

    Hürlimann, M.; Garcia-Piera, J. O.; Ledesma, A.

    2000-12-01

    Giant volcanic landslides are one of the most hazardous geological processes due to their volume and velocity. Since the 1980 eruption and associated debris avalanche of Mount St. Helens hundreds of similar events have been recognised worldwide both on continental volcanoes and volcanic oceanic islands. However, the causes and mobility of these enormous mass movements remain unresolved. Tenerife exhibits three voluminous subaerial valleys and a wide offshore apron of landslide debris produced by recurrent flank failures with ages ranging from Upper Pliocene to Middle Pleistocene. We have selected the La Orotava landslide for analysis of its causes and mobility using a variety of simple numerical models. First, the causes of the landslide have been evaluated using Limit Equilibrium Method and 2D Finite Difference techniques. Conventional parameters including hydrostatic pore pressure and material strength properties, together with three external processes, dike intrusion, caldera collapse and seismicity, have been incorporated into the stability models. The results indicate that each of the external mechanism studied is capable of initiating slope failures. However, we propose that a combination of these processes may be the most probable cause for giant volcanic landslides. Second, we have analysed the runout distance of the landslide using a simple model treating both the subaerial and submarine parts of the sliding path. The effect of the friction coefficient, drag forces and hydroplaning has been incorporated into the model. The results indicate that hydroplaning particularly can significantly increase the mobility of the landslide, which may reach runout distances greater than 70 km. The models presented are not considered definite and have mainly a conceptual purpose. However, they provide a physical basis from which to better interpret these complex geologic phenomena and should be taken into account in the prediction of future events and the assessment of

  8. Combining long- and short-term probabilistic volcanic hazard assessment with cost-benefit analysis to support decision making in a volcanic crisis from the Auckland Volcanic Field, New Zealand

    Science.gov (United States)

    Sandri, Laura; Jolly, Gill; Lindsay, Jan; Howe, Tracy; Marzocchi, Warner

    2012-04-01

    By using BET_VH, we propose a quantitative probabilistic hazard assessment for base surge impact in Auckland, New Zealand. Base surges resulting from phreatomagmatic eruptions are among the most dangerous phenomena likely to be associated with the initial phase of a future eruption in the Auckland Volcanic Field. The assessment is done both in the long-term and in a specific short-term case study, i.e. the simulated pre-eruptive unrest episode during Exercise Ruaumoko, a national civil defence exercise. The most important factors to account for are the uncertainties in the vent location (expected for a volcanic field) and in the run-out distance of base surges. Here, we propose a statistical model of base surge run-out distance based on deposits from past eruptions in Auckland and in analogous volcanoes. We then combine our hazard assessment with an analysis of the costs and benefits of evacuating people (on a 1 × 1-km cell grid). In addition to stressing the practical importance of a cost-benefit analysis in creating a bridge between volcanologists and decision makers, our study highlights some important points. First, in the Exercise Ruaumoko application, the evacuation call seems to be required as soon as the unrest phase is clear; additionally, the evacuation area is much larger than what is recommended in the current contingency plan. Secondly, the evacuation area changes in size with time, due to a reduction in the uncertainty in the vent location and increase in the probability of eruption. It is the tradeoff between these two factors that dictates which cells must be evacuated, and when, thus determining the ultimate size and shape of the area to be evacuated.

  9. Influence of particle density on flow behavior and deposit architecture of concentrated pyroclastic density currents over a break in slope: Insights from laboratory experiments

    Science.gov (United States)

    Rodriguez-Sedano, L. A.; Sarocchi, D.; Sulpizio, R.; Borselli, L.; Campos, G.; Moreno Chavez, G.

    2016-12-01

    Geological granular flows are highly complex, gravity-driven phenomena whose different behaviors depend on the mechanical properties, density and granulometric distributions of the constituent materials. Years of research have produced significant advances in understanding transport and deposition processes in granular flows. However, the role and effects of clast densities and density contrast in a granular flow are still not fully understood. In this paper we show the effect that pumice has on dry granular flows; specifically on flow velocity and longitudinal segregation of the deposits. Our work confirms, by experimental results, field observations on pumice/lithic segregation and longer pumice runout. We report results of velocity decay and deposit architecture for a granular flow passing over a break in slope (from 38° to 4° inclination). The 30 experimental runs were carried out in a five-meter long laboratory flume equipped with a series of sensors that include laser gates and high-speed cameras (400 fps). We used two polydisperse mixtures of dacitic lithics and rhyolitic pumice in varying amounts, with Weibull and Gaussian particle size distributions. The pumice/lithic ratio changes the flow response passing over a break in slope. This effect is particularly evident starting from 10% of pumice volume into the flow mixture, independently of its granulometric distribution. Runout relates to mass following a power law, with an exponent close 0.2. The experiments confirm that pumice segregation affects polydispersed mixtures, similarly to what has been observed in real field deposits, where density decoupling produces lithic-enriched proximal areas and pumice-enriched distal areas. The results obtained prove that the presence of low-density materials in a dense granular flow has a strong influence on its behavior.

  10. Monitoring of a steep rockfall area experiencing fast displacements in Kåfjord, Northern Norway

    Science.gov (United States)

    Dreiås Majala, Gudrun; Harald Blikra, Lars; Skrede, Ingrid; Kristensen, Lene

    2016-04-01

    An unstable rockfall area in Kåfjord, Northern Norway, was recognized during periodic monitoring campaigns in July and early September 2015. The LiSALab ground based Interferometric Synthethic Aperture Radar (GB InSAR) from Ellegi were used. A relatively sharply defined steep area of 1200 m2 (6.000 - 12.000 m3) was documented to be in movement. Norwegian Water Resources and Energy Directorate (NVE) was at this point performing mitigation work in terms of an embarkment within the rockfall run-out area. The monitoring system was reinstalled and adjusted to perform continuous monitoring with an early-warning aim. The section for rockslide management in NVE was responsible for the monitoring and the warning to the municipality and Police. The displacements increased from about 1 mm/day in July to 3 cm/day in mid September. People were evalcuated due to increased velocities the 16th of September. The displacements continued to increase in several stages, and with a distinct accelleration the 2nd of October. The velocity peaked in a short window to more than 200 cm/day, and it ended with a partly frontal and sideway collapse of the unstable area. However, large parts of the area stabilized again, and the run-out lengths from the small rockfalls were limited. The GB InSAR system operated exceptionally well during the event, and were able to follow continuously the displacements during the accelleration stage until collapse as the processing time window was frequently adjusted to the changes in velocity. We were also able to follow inidividual rockfalls from the images - primarily as the rockfall impact points on the slope below showed up clearly on the radar images. The area continued to stabilize due to falling temperatures, and the mitigation work were finished during the fall. The displacements seem to be correlated to the increasing temperatures in late summer and precipitation events.

  11. Investigation and hazard assessment of the 2003 and 2007 Staircase Falls rock falls, Yosemite National Park, California, USA

    Science.gov (United States)

    Wieczorek, G.F.; Stock, Gregory M.; Reichenbach, P.; Snyder, J.B.; Borchers, J.W.; Godt, J.W.

    2008-01-01

    Since 1857 more than 600 rock falls, rock slides, debris slides, and debris flows have been documented in Yosemite National Park, with rock falls in Yosemite Valley representing the majority of the events. On 26 December 2003, a rock fall originating from west of Glacier Point sent approximately 200 m 3 of rock debris down a series of joint-controlled ledges to the floor of Yosemite Valley. The debris impacted talus near the base of Staircase Falls, producing fragments of flying rock that struck occupied cabins in Curry Village. Several years later on 9 June 2007, and again on 26 July 2007, smaller rock falls originated from the same source area. The 26 December 2003 event coincided with a severe winter storm and was likely triggered by precipitation and/or frost wedging, but the 9 June and 26 July 2007 events lack recognizable triggering mechanisms. We investigated the geologic and hydrologic factors contributing to the Staircase Falls rock falls, including bedrock lithology, weathering, joint spacing and orientations, and hydrologic processes affecting slope stability. We improved upon previous geomorphic assessment of rock-fall hazards, based on a shadow angle approach, by using STONE, a three-dimensional rock-fall simulation computer program. STONE produced simulated rock-fall runout patterns similar to the mapped extent of the 2003 and 2007 events, allowing us to simulate potential future rock falls from the Staircase Falls detachment area. Observations of recent rock falls, mapping of rock debris, and simulations of rock fall runouts beneath the Staircase Falls detachment area suggest that rock-fall hazard zones extend farther downslope than the extent previously defined by mapped surface talus deposits.

  12. Dynamics of the Bingham Canyon rock avalanches (Utah, USA) resolved from topographic, seismic, and infrasound data: Bingham Canyon Rock Avalanches

    Energy Technology Data Exchange (ETDEWEB)

    Moore, Jeffrey R. [Department of Geology and Geophysics, University of Utah, Salt Lake City Utah USA; Pankow, Kristine L. [Department of Geology and Geophysics, University of Utah, Salt Lake City Utah USA; Ford, Sean R. [Atmospheric, Earth, and Energy Division, Lawrence Livermore National Laboratory, Livermore California USA; Koper, Keith D. [Department of Geology and Geophysics, University of Utah, Salt Lake City Utah USA; Hale, J. Mark [Department of Geology and Geophysics, University of Utah, Salt Lake City Utah USA; Aaron, Jordan [Department of Earth, Ocean and Atmospheric Sciences, University of British Columbia, Vancouver British Columbia Canada; Larsen, Chris F. [Geophysical Institute, University of Alaska Fairbanks, Fairbanks Alaska USA

    2017-03-01

    The 2013 Bingham Canyon Mine rock avalanches represent one of the largest cumulative landslide events in recorded U.S. history and provide a unique opportunity to test remote analysis techniques for landslide characterization. Here we combine aerial photogrammetry surveying, topographic reconstruction, numerical runout modeling, and analysis of broadband seismic and infrasound data to extract salient details of the dynamics and evolution of the multiphase landslide event. Our results reveal a cumulative intact rock source volume of 52 Mm3, which mobilized in two main rock avalanche phases separated by 1.5 h. We estimate that the first rock avalanche had 1.5–2 times greater volume than the second. Each failure initiated by sliding along a gently dipping (21°), highly persistent basal fault before transitioning to a rock avalanche and spilling into the inner pit. The trajectory and duration of the two rock avalanches were reconstructed using runout modeling and independent force history inversion of intermediate-period (10–50 s) seismic data. Intermediate- and shorter-period (1–50 s) seismic data were sensitive to intervals of mass redirection and constrained finer details of the individual slide dynamics. Back projecting short-period (0.2–1 s) seismic energy, we located the two rock avalanches within 2 and 4 km of the mine. Further analysis of infrasound and seismic data revealed that the cumulative event included an additional 11 smaller landslides (volumes ~104–105 m3) and that a trailing signal following the second rock avalanche may result from an air-coupled Rayleigh wave. Our results demonstrate new and refined techniques for detailed remote characterization of the dynamics and evolution of large landslides.

  13. The disastrous 17 February 2006 rockslide-debris avalanche on Leyte Island, Philippines: a catastrophic landslide in tropical mountain terrain

    Directory of Open Access Journals (Sweden)

    S. G. Evans

    2007-01-01

    Full Text Available In February 2006, a disastrous rockslide-debris avalanche occurred in tropical mountain terrain, on Leyte Island, Central Philippines. Over 1100 people perished when the village of Guinsaugon was overwhelmed directly in the path of the landslide. The landslide was initiated by the failure of a 450 m high rock slope within the damage zone of the Philippine Fault where the rock mass consisted of sheared and brecciated volcanic, sedimentary and volcaniclastic rocks. Tectonic weakening of the failed rock mass had resulted from active strike-slip movements along the Philippine Fault which have been estimated by other workers at 2.5 cm/year. The landslide involved a total volume of 15 Mm3, including significant entrainment from its path, and ran out a horizontal distance of 3800 m over a vertical distance of 810 m, equivalent to a fahrböschung of 12°. Run-out distance was enhanced by friction reduction due to undrained loading when the debris encountered flooded paddy fields in the valley bottom at a path distance of 2600 m. A simulation of the event using the dynamic analysis model DAN indicated a mean velocity of 35 m/s and demonstrated the contribution of the paddy field effect to total run-out distance. There was no direct trigger for the landslide but the landslide did follow a period of very heavy rainfall with a lag time of four days. The rockslide-debris avalanche is one of several disastrous landslides to have occurred in the Philippines in the last twenty years. In terms of loss of life, the Guinsaugon event is the most devastating single-event landslide to have occurred worldwide since the Casita Volcano rock avalanche-debris flow which was triggered by Hurricane Mitch in Nicaragua in 1998.

  14. Structurally controlled hazard mapping of Southern Leyte, Philippines

    Science.gov (United States)

    Luzon, P. K.; Montalbo, K. P.; Galang, J. A. M.; Sabado, J. M.; Escape, C. M.; Felix, R. P.; Lagmay, A. M. F.

    2015-10-01

    The 2006 Guinsaugon landslide in St. Bernard, Southern Leyte is one of the largest known landslides in the Philippines in recent history. It consists of a 15-20 million m3 rockslide-debris avalanche from an approximately 675 m high mountain weakened by continuous movement of the Philippine fault. The catastrophic Guinsaugon landslide killed 1221 people and displaced 19 000 residents over its 4.5 km path. To investigate the present day morphology of the scar and potential failure that may occur, analysis of a 5 m resolution IfSAR-derived Digital Elevation Model was conducted using Coltop3D and Matterocking software, leading to the generation of a landslide hazard map for the province of Southern Leyte in Central Philippines. The dip and dip-direction of discontinuity sets that contribute to gravitational failure in mountainous areas of the province were identified and measured using a lower Schmidt-Lambert color scheme. After measurement of the morpho-structural orientations, potential sites of failure were analyzed. Conefall was then utilized to compute the extent of rock mass runout. Results of the analysis show instability in the scarp area of the 2006 Guinsaugon landslide and in adjacent slopes because of the presence of steep discontinuities that range from 45-60°. Apart from the 2006 Guinsaugon landslide site, runout models simulated farther rock mass extent in its adjacent slopes, revealing a high potential for fatal landslides to happen in the municipality of St. Bernard. Concerned agencies may use maps produced in the same manner as this study to identify possible sites where structurally-controlled landslides can occur. In a country like the Philippines, where fractures and faults are common, this type of simulated hazard maps would be useful for disaster prevention and facilitate disaster risk reduction efforts for landslide-susceptible areas.

  15. Hazard mapping related to structurally controlled landslides in Southern Leyte, Philippines

    Science.gov (United States)

    Luzon, Paul Kenneth; Montalbo, Kristina; Galang, Jam; Sabado, Jasmine May; Escape, Carmille Marie; Felix, Raquel; Mahar Francisco Lagmay, Alfredo

    2016-04-01

    The 2006 Guinsaugon landslide in Saint Bernard, Southern Leyte, is one of the largest known landslides in the Philippines in recent history. It consists of a 15-20 million m3 rockslide-debris avalanche from an approximately 675 m high mountain weakened by continuous movement of the Philippine Fault. The catastrophic Guinsaugon landslide killed 1221 people and displaced 19 000 residents over its 4.5 km path. To investigate the present-day morphology of the scar and potential failure that may occur, analysis of a 5 m resolution InSAR-derived digital elevation model was conducted using Coltop3D and Matterocking software, leading to the generation of a landslide hazard map for the province of Southern Leyte in central Philippines. The dip and dip direction of discontinuity sets that contribute to gravitational failure in mountainous areas of the province were identified and measured using a lower Schmidt-Lambert color scheme. After measurement of the morpho-structural orientations, potential sites of failure were analyzed. Conefall was then utilized to compute the extent of rock mass runout. Results of the analysis show instability in the scarp area of the 2006 Guinsaugon landslide and in adjacent slopes because of the presence of steep discontinuities that range from 45 to 60°. Apart from the 2006 Guinsaugon landslide site, runout models simulated farther rock mass extent in its adjacent slopes, revealing a high potential for fatal landslides to happen in the municipality of Saint Bernard. Concerned agencies may use maps produced in the same manner as this study to identify possible sites where structurally controlled landslides can occur. In a country like the Philippines, where fractures and faults are common, this type of simulated hazard maps would be useful for disaster prevention and facilitate disaster risk reduction efforts for landslide-susceptible areas.

  16. The disastrous 17 February 2006 rockslide-debris avalanche on Leyte Island, Philippines: a catastrophic landslide in tropical mountain terrain

    Science.gov (United States)

    Evans, S. G.; Guthrie, R. H.; Roberts, N. J.; Bishop, N. F.

    2007-01-01

    In February 2006, a disastrous rockslide-debris avalanche occurred in tropical mountain terrain, on Leyte Island, Central Philippines. Over 1100 people perished when the village of Guinsaugon was overwhelmed directly in the path of the landslide. The landslide was initiated by the failure of a 450 m high rock slope within the damage zone of the Philippine Fault where the rock mass consisted of sheared and brecciated volcanic, sedimentary and volcaniclastic rocks. Tectonic weakening of the failed rock mass had resulted from active strike-slip movements along the Philippine Fault which have been estimated by other workers at 2.5 cm/year. The landslide involved a total volume of 15 Mm3, including significant entrainment from its path, and ran out a horizontal distance of 3800 m over a vertical distance of 810 m, equivalent to a fahrböschung of 12°. Run-out distance was enhanced by friction reduction due to undrained loading when the debris encountered flooded paddy fields in the valley bottom at a path distance of 2600 m. A simulation of the event using the dynamic analysis model DAN indicated a mean velocity of 35 m/s and demonstrated the contribution of the paddy field effect to total run-out distance. There was no direct trigger for the landslide but the landslide did follow a period of very heavy rainfall with a lag time of four days. The rockslide-debris avalanche is one of several disastrous landslides to have occurred in the Philippines in the last twenty years. In terms of loss of life, the Guinsaugon event is the most devastating single-event landslide to have occurred worldwide since the Casita Volcano rock avalanche-debris flow which was triggered by Hurricane Mitch in Nicaragua in 1998.

  17. Optical sensor for precision in-situ spindle health monitoring

    Science.gov (United States)

    Zhao, Rui

    An optical sensor which can record in-situ measurements of the dynamic runout of a precision miniature spindle system in a simple and low-cost manner is proposed in this dissertation. Spindle error measurement technology utilizes a cylindrical or spherical target artifact attached to the miniature spindle with non-contact sensors, typically capacitive sensors which are calibrated with a flat target surface not a curved target surface. Due to the different behavior of an electric field between a flat plate and a curved surface and an electric field between two flat plates, capacitive sensors is not suitable for measuring target surfaces smaller than its effective sensing area. The proposed sensor utilizes curved-edge diffraction (CED), which uses the effect of cylindrical surface curvature on the diffraction phenomenon in the transition regions adjacent to shadow, transmission, and reflection boundaries. The laser diodes light incident on the cylindrical surface of precision spindle and photodetectors collect the total field produced by the diffraction around the target surface. Laser diode in the different two direction are incident to the spindle shaft edges along the X and Y axes, four photodetectors collect the total fields produced by interference of multiple waves due to CED around the spindle shaft edges. The X and Y displacement can be obtained from the total fields using two differential amplifier configurations, respectively. Precision miniature spindle (shaft φ5.0mm) runout was measured, and the proposed sensor can perform curve at the different speed of rotation from 1500rpm to 8000rpm in the X and Y axes, respectively. On the other hand, CED also show changes for different running time and temperature of spindle. These results indicate that the proposed sensor promises to be effective for in-situ monitoring of the miniature spindle's health with high resolution, wide bandwidth, and low-cost.

  18. Suitability of energy cone for probabilistic volcanic hazard assessment: validation tests at Somma-Vesuvius and Campi Flegrei (Italy)

    Science.gov (United States)

    Tierz, Pablo; Sandri, Laura; Costa, Antonio; Zaccarelli, Lucia; Di Vito, Mauro Antonio; Sulpizio, Roberto; Marzocchi, Warner

    2016-11-01

    Pyroclastic density currents (PDCs) are gravity-driven hot mixtures of gas and volcanic particles which can propagate at high speed and cover distances up to several tens of kilometers around a given volcano. Therefore, they pose a severe hazard to the surroundings of explosive volcanoes able to produce such phenomena. Despite this threat, probabilistic volcanic hazard assessment (PVHA) of PDCs is still in an early stage of development. PVHA is rooted in the quantification of the large uncertainties (aleatory and epistemic) which characterize volcanic hazard analyses. This quantification typically requires a big dataset of hazard footprints obtained from numerical simulations of the physical process. For PDCs, numerical models range from very sophisticated (not useful for PVHA because of their very long runtimes) to very simple models (criticized because of their highly simplified physics). We present here a systematic and robust validation testing of a simple PDC model, the energy cone (EC), to unravel whether it can be applied to PVHA of PDCs. Using past PDC deposits at Somma-Vesuvius and Campi Flegrei (Italy), we assess the ability of EC to capture the values and variability in some relevant variables for hazard assessment, i.e., area of PDC invasion and maximum runout. In terms of area of invasion, the highest Jaccard coefficients range from 0.33 to 0.86 which indicates an equal or better performance compared to other volcanic mass-flow models. The p values for the observed maximum runouts vary from 0.003 to 0.44. Finally, the frequencies of PDC arrival computed from the EC are similar to those determined from the spatial distribution of past PDC deposits, with high PDC-arrival frequencies over an ˜8-km radius from the crater area at Somma-Vesuvius and around the Astroni crater at Campi Flegrei. The insights derived from our validation tests seem to indicate that the EC is a suitable candidate to compute PVHA of PDCs.

  19. Modeling rockfall frequency and bounce height from three-dimensional simulation process models and growth disturbances in submontane broadleaved trees

    Science.gov (United States)

    Corona, Christophe; Lopez-Saez, Jérôme; Favillier, Adrien; Mainieri, Robin; Eckert, Nicolas; Trappmann, Daniel; Stoffel, Markus; Bourrier, Franck; Berger, Frédéric

    2017-03-01

    The use of dynamic computational methods has become indispensable for the assessment of rockfall hazards and the quantification of uncertainties. Although a substantial number of models with various degrees of complexity has become available over the past few years, models have only rarely been parameterized against observations, especially because long-term records of rockfalls have proven to be scarce and typically incomplete. On forested slopes, tree-ring analyses may help to fill this gap, as they have been shown to provide annually resolved data on past rockfall activity over long periods. In this paper, a total of 1495 rockfall scars recorded on the stem surface of 1004 trees have been studied at a site in the Vercors massif (French Alps) to calibrate the 3D process based simulation model RockyFor3D. Uncertainties related to the choice of parameters accounting for energy dissipation and surface roughness have been investigated in detail. Because of the lack of reliable data, these parameters typically are estimated based on expert judgments, despite the fact that they have significant impacts on runout distances and bounce height. We demonstrate that slight variations in roughness can indeed strongly affect the performance of runout modeling and that the decreasing downward gradient, observed in field data, is properly reproduced only if reduced roughness (< 10 cm) enables blocks to reach the distal parts of the study plot. With respect to the height of impacts, our results also reveal that differences between simulations and observations can indeed be minimized if softer soil types are preferred during simulation, as they typically limit bouncing. We conclude that field-based dendrogeomorphic approaches represent an objective tool to improve rockfall simulations and to enhance our understanding of parameterization, which is of key importance for process dynamics and thus hazard zoning.

  20. How are giant clasts incorporated into submarine landslides and how do they change flow dynamics?

    Science.gov (United States)

    Ortiz-Karpf, A.; Hodgson, D.; Jackson, C. A. L.; Spychala, Y.; Hannah, B. L.; McCaffrey, W. D.

    2015-12-01

    Giant clasts (>10,000 m3) are common in many submarine landslide deposits. Here, we use submarine landslide deposits exposed in the field (Karoo Basin, South Africa and Neuquén Basin, Argentina) and imaged in high-resolution reflection seismic data (offshore Colombia and offshore Brazil) to investigate how giant clasts were entrained and transported in the parent flows, and how they changed longitudinal flow behaviour. Based on: (i) facies/seismic facies similarities between clast and substrate; (ii) evidence for basal scour at a scale comparable to the clasts; and (iii) the spatial association of scours and clasts, we are able to discriminate between clasts derived from the substrate during flow run-out rather than from headwall degradation. Highly sheared basal surfaces are well-developed in distal locations, sometimes extending beyond the deposit. This points to deformation and weakening of the substrate ahead of the flow, thus providing a potential mechanism to entrain large clasts on low gradients in the absence of basal flow turbulence. Scours and ramps on the basal shear surface, which are associated with concentrations of large clasts, commonly occur where bathymetric changes are abrupt (confinement and/or steepening) or where more easily eroded substrate are encountered (e.g. sand-prone channel-fills). Substrate entrainment bulks the flow volume along during flow evolution, thereby increasing mass and momentum. Our outcrop and subsurface examples point to a complicated interplay between flow evolution, bathymetry, and substrate geology, which combine to control the development of the basal shear surface. Improved understanding of these interrelationships will help to refine the estimates of the volumes and runout distances, and therefore geohazard potential, of submarine landslides.

  1. Fatigue of a 3D Orthogonal Non-crimp Woven Polymer Matrix Composite at Elevated Temperature

    Science.gov (United States)

    Wilkinson, M. P.; Ruggles-Wrenn, M. B.

    2017-02-01

    Tension-tension fatigue behavior of two polymer matrix composites (PMCs) was studied at elevated temperature. The two PMCs consist of the NRPE polyimide matrix reinforced with carbon fibers, but have different fiber architectures: the 3D PMC is a singly-ply non-crimp 3D orthogonal weave composite and the 2D PMC, a laminated composite reinforced with 15 plies of an eight harness satin weave (8HSW) fabric. In order to assess the performance and suitability of the two composites for use in aerospace components designed to contain high-temperature environments, mechanical tests were performed under temperature conditions simulating the actual operating conditions. In all elevated temperature tests performed in this work, one side of the test specimen was at 329 °C while the other side was open to ambient laboratory air. The tensile stress-strain behavior of the two composites was investigated and the tensile properties measured for both on-axis (0/90) and off-axis (±45) fiber orientations. Elevated temperature had little effect on the on-axis tensile properties of the two composites. The off-axis tensile strength of both PMCs decreased slightly at elevated temperature. Tension-tension fatigue tests were conducted at elevated temperature at a frequency of 1.0 Hz with a ratio of minimum stress to maximum stress of R = 0.05. Fatigue run-out was defined as 2 × 105 cycles. Both strain accumulation and modulus evolution during cycling were analyzed for each fatigue test. The laminated 2D PMC exhibited better fatigue resistance than the 3D composite. Specimens that achieved fatigue run-out were subjected to tensile tests to failure to characterize the retained tensile properties. Post-test examination under optical microscope revealed severe delamination in the laminated 2D PMC. The non-crimp 3D orthogonal weave composite offered improved delamination resistance.

  2. A study of the Taisho lahar generated by the 1926 eruption of Tokachidake Volcano, central Hokkaido, Japan, and implications for the generation of cohesive lahars

    Science.gov (United States)

    Uesawa, Shimpei

    2014-01-01

    Understanding the generation mechanisms of lahars is important for improving volcanic hazard assessments. The Taisho lahar (TL) was generated during the 1926 eruption of Tokachidake Volcano, Japan, and was considered a typical snowmelt lahar caused by the runout of hot debris onto a snow-covered slope. A similar mechanism produced a huge mud flow during the 1985 eruption of Nevado del Ruiz, Colombia. However, the origin of water in such lahars remains a controversial topic because the calculated water mass is based on the assumption that all of the snow on the runout area of the TL was melted, although this is much less than the estimated water volume in the TL estimated by previous studies. I have re-examined proximal deposits of the TL and their paleomagnetic characteristics in order to better understand the eruption sequence and formation of the TL. The TL produced two debris avalanche deposits and a surge-like deposit that had relatively high emplacement temperature (~ 350 °C). The deposits are composed of hydrothermally altered andesitic gravel, sand and mud. The high clay content (3-5 wt.% clay in the pyroclastic cone (hypocenter). The presence of the surge deposit indicates that the TL was not caused by simple collapse of a cinder cone but by a phreatic explosion that resulted in sector collapse. This suggests that the hydrothermal system was related to the 1926 eruption. The present-day volcano has a large hydrothermal system (1 × 106 m3 water) beneath the active crater. This study indicates that hydrothermal system explosions can trigger cohesive lahars that contain both snow melt and hydrothermal pore water, and this indicates the need to monitor hydrothermal systems.

  3. The Characteristics and triggering Factors of the October 2013 Obudu International Tourist Centre catastrophic Landslide South-East Nigeria

    Science.gov (United States)

    Fukuoka, Hiroshi; Igwe, Ogbonnaya

    2015-04-01

    The October 2013 catastrophic landslides at the Obudu international tourist zone south-east Nigeria destroyed resources worth several millions of dollars and trapped international tourist who were later rescued by a helicopter. Intense rainfall caused several slope failures on the steep slopes of the hills. These landslides occurred after several days of heavy rain (> 600 mm) and were the first reported slope failures in this region. The failures were on a predominantly metamorphic terrain and only on slopes adjacent to the main road. They occurred as slides, not debris flow, but produced a wide range of casualties. The failures were of residual materials (about 1 m thick) obtained from weathering of schist. One of the landslides involved the movement of about 70,000 m3 debris for 8.6 m with depth of slip surface of 6 m. Another, which produced the most fatality initiated on a slope greater than 40o and displaced about 77, 000 m3. It had a runout length of 60 m, width of 98 m, depth to slip surface of 8 m and depositional area of about 2,500 m2. Had the opposite slope bounding the other side of the road not hindered the movement of debris, the runout distance could have been larger. The research found that all the landslides occurred on slope-portions composed of schist rather than gneiss or granite. Slip surfaces developed within the regolith and the shear zone was characterized by the presence of silty materials supported by clayey matrix. Field observations indicated that the failures generally developed as localized translational slides within the semi-consolidated, cohesive soil units (with high plasticity and low strength) within the upper to middle weathered zone of the schist. The increase in pore pressure arising from elevated water table during rainfall created instability by weakening the shear strength along the failure plane. However, differences in permeability favored the formation of perched water table which eventually triggered sliding.

  4. Multi-temporal LiDAR-DTMs as a tool for modelling a complex landslide: a case study in the Rotolon catchment (eastern Italian Alps)

    Science.gov (United States)

    Bossi, G.; Cavalli, M.; Crema, S.; Frigerio, S.; Luna, B. Quan; Mantovani, M.; Marcato, G.; Schenato, L.; Pasuto, A.

    2015-04-01

    The geomorphological change detection through the comparison of repeated topographic surveys is a recent approach that benefits greatly from the latest developments in topographical data acquisition techniques. Among them, airborne LiDAR makes the monitoring of geomorphological changes a more reliable and accurate approach for natural hazard and risk management. In this study, two LiDAR digital terrain models (DTMs) (2 m resolution) were acquired just before and after a complex 340 000 m3 landslide event (4 November 2010) that generated a debris flow in the channel of the Rotolon catchment (eastern Italian Alps). The analysis of these data was used to set up the initial condition for the application of a dynamic model. The comparison between the pre- and post-event DTMs allowed us to identify erosion and depositional areas and the volume of the landslide. The knowledge of the phenomenon dynamics was the base of a sound back analysis of the event with the 3-D numerical model DAN3D. This particular code was selected for its capability to modify the rheology and the parameters of the moving mass during run-out, as actually observed along the path of the 2010 debris flow. Nowadays some portions of Mt. Rotolon flank are still moving and show signs of detachment. The same soil parameters used in the back-analysis model could be used to simulate the run-out for possible future landslides, allowing us to generate reliable risk scenarios useful for awareness of civil defense and strategy of emergency plans.

  5. Calibration of numerical models for small debris flows in Yosemite Valley, California, USA

    Science.gov (United States)

    Bertolo, P.; Wieczorek, G.F.

    2005-01-01

    This study compares documented debris flow runout distances with numerical simulations in the Yosemite Valley of California, USA, where about 15% of historical events of slope instability can be classified as debris flows and debris slides (Wieczorek and Snyder, 2004). To model debris flows in the Yosemite Valley, we selected six streams with evidence of historical debris flows; three of the debris flow deposits have single channels, and the other three split their pattern in the fan area into two or more channels. From field observations all of the debris flows involved coarse material, with only very small clay content. We applied the one dimensional DAN (Dynamic ANalysis) model (Hungr, 1995) and the two-dimensional FLO2D model (O'Brien et al., 1993) to predict and compare the runout distance and the velocity of the debris flows observed in the study area. As a first step, we calibrated the parameters for the two softwares through the back analysis of three debris- flows channels using a trial-and-error procedure starting with values suggested in the literature. In the second step we applied the selected values to the other channels, in order to evaluate their predictive capabilities. After parameter calibration using three debris flows we obtained results similar to field observations We also obtained a good agreement between the two models for velocities. Both models are strongly influenced by topography: we used the 30 m cell size DTM available for the study area, that is probably not accurate enough for a highly detailed analysis, but it can be sufficient for a first screening. European Geosciences Union ?? 2005 Author(s). This work is licensed under a Creative Commons License.

  6. Investigation and hazard assessment of the 2003 and 2007 Staircase Falls rock falls, Yosemite National Park, California, USA

    Directory of Open Access Journals (Sweden)

    G. F. Wieczorek

    2008-05-01

    Full Text Available Since 1857 more than 600 rock falls, rock slides, debris slides, and debris flows have been documented in Yosemite National Park, with rock falls in Yosemite Valley representing the majority of the events. On 26 December 2003, a rock fall originating from west of Glacier Point sent approximately 200 m3 of rock debris down a series of joint-controlled ledges to the floor of Yosemite Valley. The debris impacted talus near the base of Staircase Falls, producing fragments of flying rock that struck occupied cabins in Curry Village. Several years later on 9 June 2007, and again on 26 July 2007, smaller rock falls originated from the same source area. The 26 December 2003 event coincided with a severe winter storm and was likely triggered by precipitation and/or frost wedging, but the 9 June and 26 July 2007 events lack recognizable triggering mechanisms. We investigated the geologic and hydrologic factors contributing to the Staircase Falls rock falls, including bedrock lithology, weathering, joint spacing and orientations, and hydrologic processes affecting slope stability. We improved upon previous geomorphic assessment of rock-fall hazards, based on a shadow angle approach, by using STONE, a three-dimensional rock-fall simulation computer program. STONE produced simulated rock-fall runout patterns similar to the mapped extent of the 2003 and 2007 events, allowing us to simulate potential future rock falls from the Staircase Falls detachment area. Observations of recent rock falls, mapping of rock debris, and simulations of rock fall runouts beneath the Staircase Falls detachment area suggest that rock-fall hazard zones extend farther downslope than the extent previously defined by mapped surface talus deposits.

  7. In vitro Doppler ultrasound investigation of turbulence intensity in pulsatile flow with simulated cardiac variability.

    Science.gov (United States)

    Thorne, Meghan L; Poepping, Tamie L; Nikolov, Hristo N; Rankin, Richard N; Steinman, David A; Holdsworth, David W

    2009-01-01

    An in vitro investigation of turbulence intensity (TI) associated with a severe carotid stenosis in the presence of physiological cardiac variability is described. The objective of this investigation was to determine if fluctuations due to turbulence could be quantified with conventional Doppler ultrasound (DUS) in the presence of normal physiological cycle-to-cycle cardiac variability. An anthropomorphic model of a 70% stenosed carotid bifurcation was used in combination with a programmable flow pump to generate pulsatile flow with a mean flow rate of 6 mL/s. Utilizing the pump, we studied normal, nonrepetitive cycle-to-cycle cardiac variability (+/-3.9%) in flow, as well as waveform shapes with standard deviations equal to 0, 2 and 3 times the normal variation. Eighty cardiac cycles of Doppler data were acquired at two regions within the model, representing either laminar or turbulent flow; each measurement was repeated six times. Turbulence intensity values were found to be 11 times higher (p laminar region, with a mean difference of 24 cm/s. Twenty cardiac cycles were required for confidence in TI values. In conclusion, these results indicate that it is possible to quantify TI in vitro, even in the presence of normal and exaggerated cycle-to-cycle cardiac variability.

  8. Escherichia coli biofilms: Accepting the therapeutic challenges

    Directory of Open Access Journals (Sweden)

    Trupti Bajpai

    2016-01-01

    Full Text Available Background: Urinary tract infections (UTI′s are a major public health concern globally. Recurrent UTI′s that are predominantly caused by uropathogenic Escherichia coli′s forms biofilm that is an intracellular, structured bacterial community, enclosed in a self-produced matrix, adherent to an inert, or living surface. Biofilm physiology is characterized by increased tolerance to stress, antibiotics, and immunological defenses, which is at the origin of their resilience in most medical and industrial settings. Materials and Methods: The present prospective study was carried out from December 2013 to May 2014 in the Department of Microbiology of a Teaching Tertiary Care hospital located in central India. A total of 100 consecutive, nonrepetitive E. coli isolates were subjected to biofilm formation study by Christensen′s tube adherence method. All the isolates were also subjected to antimicrobial susceptibility testing by Kirby-Bauer disc diffusion method in accordance with the Clinical Laboratory Standard Institute 2013 guidelines. Results and Discussion: Out of the 100 E. coli isolates studied, 62 (62% were positive for biofilm formation. High percentage of resistance was detected in isolates among the male inpatient group. Overall drug resistance was found to be very high among both biofilm as well as nonbiofilm forming isolates indicating excessive drug resistance among both community and hospital organisms. Conclusion: A greater understanding of the nature of biofilm organisms in chronic UTI′s would help in the development of novel and more effective treatments for these problematic diseases.

  9. A distortion-correction method for workshop machine vision measurement system

    Science.gov (United States)

    Chen, Ruwen; Huang, Ren; Zhang, Zhisheng; Shi, Jinfei; Chen, Zixin

    2008-12-01

    The application of machine vision measurement system is developing rapidly in industry for its non-contact, high speed, and automation characteristics. However, there are nonlinear distortions in the images which are vital to measuring precision, for the object dimensions are determined by the image properties. People are interested in this problem and put forward some physical model based correction methods which are widely applied in engineering. However, these methods are difficult to be realized in workshop for the images are non-repetitive interfered by the coupled dynamic factors, which means the real imaging is a stochastic process. A new nonlinear distortion correction method based on a VNAR model (Volterra series based nonlinear auto-regressive time series model) is proposed to describe the distorted image edge series. The model parameter vectors are achieved by the laws of data. The distortion-free edges are obtained after model filtering and the image dimensions are transformed to measuring dimensions. Experimental results show that the method is reliable and can be applied to engineering.

  10. Incidence of Extended-Spectrum β-Lactamases and Characterization of Integrons in Extended-Spectrum β-Lactamase-producing Klebsiella pneumoniae Isolated in Shantou, China

    Institute of Scientific and Technical Information of China (English)

    Fen YAO; Yuanshu QIAN; Shuzhen CHEN; Peifen WANG; Yuanchun HUANG

    2007-01-01

    This study is concerned with the level of antibiotic resistance of extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae, isolated in Shantou, China, and its mechanism. Seventyfour non-repetitive clinical isolates of K. pneumoniae producing ESBLs were isolated over a period of 2 years. Antibiotic susceptibility, carried out by Epsilometer test, showed that most of the isolates were multiresistant. Polymerase chain reaction showed that, among the several types of β-lactamases, SHV was the most prevalent, TEM was the second most prevalent, and CTX-M was the least prevalent. Sixty-nine isolates were positive for integrase gene IntI1, but no IntI2 or IntI3 genes were found. The variable region of class 1 integrons were amplified and further identified by sequencing. Thirteen different gene cassettes and 11 different cassette combinations were detected. Dfr and aadA cassettes were predominant and cassette combinations dfrA12, orfF and aadA2 were most frequently found. No gene cassettes encoding ESBLs were found. Integrons were prevalent and played an important role in multidrug resistance in ESBL-producing K. pneumoniae.

  11. Concomitant detection of biofilm and metallo-beta-lactamases production in gram-negative bacilli.

    Science.gov (United States)

    Singhai, Monil; Rawat, Vinita; Goyal, Rajeev

    2013-01-01

    Carbapenems are mainstay of treating serious multidrug resistant gram-negative biofilm-based infections. However, recent emergence of metallo-beta-lactamases (MbL) producing gram-negative bacilli in different parts of world may be related to gain of virulence factors associated with biofilm production. To explore the association of MbL and biofilm production in various gram-negative bacilli. In this study, 110 non-repetitive ceftazidime resistant gram-negative bacilli were evaluated for biofilm and MβL production. Biofilm forming ability of isolates obtained from various specimens was tested by the tube method. Disks of ceftazidime (30 μg) and ceftazidime with ethylenediaminetetraacetic acid (30 μg + 750 μg, prepared in house) for MβL detection were used. Chi-square test was used to study the association between biofilm and MβL production. P value bacilli had shown biofilm producing ability. The association of biofilm and MβL was significant in cases of non-fermenters as compared to enterobacteriaceae members. The particular combination of virulence factors (biofilm and MβL) in bacteria may be a species specific effect which needs to be investigated at molecular level in detail. This may help in designing newer therapies based on interference with biofilm formation and thus countering clinical episodes of antibiotic resistance.

  12. Antibiotic resistance and OXA-type carbapenemases-encoding genes in airborne Acinetobacter baumannii isolated from burn wards.

    Science.gov (United States)

    Gao, Jing; Zhao, Xiaonan; Bao, Ying; Ma, Ruihua; Zhou, Yufa; Li, Xinxian; Chai, Tongjie; Cai, Yumei

    2014-03-01

    The study was conducted to investigate drug resistance, OXA-type carbapenemases-encoding genes and genetic diversity in airborne Acinetobacter baumannii (A. baumannii) in burn wards. Airborne A. baumannii were collected in burn wards and their corridors using Andersen 6-stage air sampler from January to June 2011. The isolates susceptibility to 13 commonly used antibiotics was examined according to the CLSI guidelines; OXA-type carbapenemases-encoding genes and molecular diversity of isolates were analyzed, respectively. A total of 16 non-repetitive A. baumannii were isolated, with 10 strains having a resistance rate of greater than 50% against the 13 antibiotics. The resistance rate against ceftriaxone, cyclophosvnamide, ciprofloxacin, and imipenem was 93.75% (15/16), but no isolate observed to be resistant to cefoperazone/sulbactam. Resistance gene analyses showed that all 16 isolates carried OXA-51, and 15 isolates carried OXA-23 except No.15; but OXA-24 and OXA-58 resistance genes not detected. The isolates were classified into 13 genotypes (A-M) according to repetitive extragenic palindromic sequence PCR (REP-PCR) results and only six isolates had a homology ≥90%. In conclusion, airborne A. baumannii in the burn wards had multidrug resistance and complex molecular diversity, and OXA-23 and OXA-51 were dominant mechanisms for resisting carbapenems.

  13. The Complete Mitochondrial Genome of Ctenoptilum vasava (Lepidoptera: Hesperiidae: Pyrginae and Its Phylogenetic Implication

    Directory of Open Access Journals (Sweden)

    Jiasheng Hao

    2012-01-01

    Full Text Available We here report the first complete mitochondrial (mt genome of a skipper, Ctenoptilum vasava Moore, 1865 (Lepidoptera: Hesperiidae: Pyrginae. The mt genome of the skipper is a circular molecule of 15,468 bp, containing 2 ribosomal RNA genes, 24 putative transfer RNA (tRNA, genes including an extra copy of trnS (AGN and a tRNA-like insertion trnL (UUR, 13 protein-coding genes and an AT-rich region. All protein-coding genes (PCGs are initiated by ATN codons and terminated by the typical stop codon TAA or TAG, except for COII which ends with a single T. The intergenic spacer sequence between trnS (AGN and ND1 genes also contains the ATACTAA motif. The AT-rich region of 429 bp is comprised of nonrepetitive sequences, including the motif ATAGA followed by an 19 bp poly-T stretch, a microsatellite-like (AT3 (TA9 element next to the ATTTA motif, an 11 bp poly-A adjacent to tRNAs. Phylogenetic analyses (ML and BI methods showed that Papilionoidea is not a natural group, and Hesperioidea is placed within the Papilionoidea as a sister to ((Pieridae + Lycaenidae + Nymphalidae while Papilionoidae is paraphyletic to Hesperioidea. This result is remarkably different from the traditional view where Papilionoidea and Hesperioidea are considered as two distinct superfamilies.

  14. Supreme Court Position Regarding the Implementation of International Law Crimes of the Past in Spain: a Legal Analysis after Reports of the un Working Group on Enforced Disappearance, the Committee on Enforced Disappearances and the un Special Rapporteur

    Directory of Open Access Journals (Sweden)

    Javier Chinchón Álvarez

    2014-10-01

    Full Text Available Along with the undeniable importance of the case, the judgment of the Spanish Supreme Court in the trial against Judge Baltasar Garzón accused of prevarication, having declared itself competent to investigate complaints for crimes committed during the Civil War and the Franco’s regime, it has had a determining significance: from then to now, the doctrine of the High Court has been almost literally followed by the remaining Spanish courts against any complaint concerning to crimes com- mitted before the last transition to democracy in Spain. This state of affairs has been repeatedly criticized by various bodies of the United Nations, expressly by the three that have visited Spain more recently: The UN Working Group on Enforced or Involuntary Disappearances, the Committee on Enforced Disappearances and the UN Special Rapporteur on the Promotion of Truth, Justice, Reparation and Guarantees of Non-Repetition. In this contribution will be presented and analysed transcendent positions defended by the Supreme Court regarding the application of international law to the past crimes in Spain and especially its configuration as crimes against humanity, the legal assessment about the enforced disappearance, and the validity and application of the 1977 Amnesty Law.

  15. Assessment of distance-based multi-attribute group decision-making methods from a maintenance strategy perspective

    Science.gov (United States)

    Ding, Siew-Hong; Kamaruddin, Shahrul

    2015-07-01

    Maintenance has been acknowledged by industrial management as a significant influencing factor of plant performance. Effective plant maintenance can be realized by developing a proper maintenance strategy. However, selecting an appropriate maintenance strategy is difficult because maintenance is a non-repetitive task such as production activity. Maintenance also does not leave a consistent traceable record that can be referred to during the decision-making process. The involvement of tangible and intangible factors in the assessment process further increases the complexity of the decision-making process. The technique of preference order by similarity to ideal solution (TOPSIS) is one of the most well-known decision-making methods and has been widely used by organizations to conduct effective decisions regarding maintenance issues. TOPSIS has also evolved by integrating different approaches such as the fuzzy concept. Although numerous TOPSIS applications for maintenance decision making have been published, the effectiveness of crisp TOPSIS and fuzzy TOPSIS needs to be investigated further. This paper attempts to present a comparison between conventional crisp TOPSIS and fuzzy TOPSIS from a group maintenance decision-making perspective by an empirical illustration. Sensitivity analysis is conducted to demonstrate further the resilience of crisp TOPSIS and fuzzy TOPSIS.

  16. The RING finger/B-Box factor TAM-1 and a retinoblastoma-like protein LIN-35 modulate context-dependent gene silencing in Caenorhabditis elegans

    Science.gov (United States)

    Hsieh, Jenny; Liu, Jing; Kostas, Stephen A.; Chang, Chieh; Sternberg, Paul W.; Fire, Andrew

    1999-01-01

    Context-dependent gene silencing is used by many organisms to stably modulate gene activity for large chromosomal regions. We have used tandem array transgenes as a model substrate in a screen for Caenorhabditis elegans mutants that affect context-dependent gene silencing in somatic tissues. This screen yielded multiple alleles of a previously uncharacterized gene, designated tam-1 (for tandem-array-modifier). Loss-of-function mutations in tam-1 led to a dramatic reduction in the activity of numerous highly repeated transgenes. These effects were apparently context dependent, as nonrepetitive transgenes retained activity in a tam-1 mutant background. In addition to the dramatic alterations in transgene activity, tam-1 mutants showed modest alterations in expression of a subset of endogenous cellular genes. These effects include genetic interactions that place tam-1 into a group called the class B synMuv genes (for a Synthetic Multivulva phenotype); this family plays a negative role in the regulation of RAS pathway activity in C. elegans. Loss-of-function mutants in other members of the class-B synMuv family, including lin-35, which encodes a protein similar to the tumor suppressor Rb, exhibit a hypersilencing in somatic transgenes similar to that of tam-1 mutants. Molecular analysis reveals that tam-1 encodes a broadly expressed nuclear protein with RING finger and B-box motifs. PMID:10580003

  17. Metallo-β-lactamase-producing Pseudomonas aeruginosa in two hospitals from southern Brazil

    Directory of Open Access Journals (Sweden)

    Fernanda W. Wirth

    2009-06-01

    Full Text Available This study determined the prevalence of metallo-β-lactamase (MBL-producing Pseudomonas aeruginosa in two hospitals located in the Southern part of Brazil and compare the performance of two different phenotypic tests. Thirty-one non-repetitive Pseudomonas aeruginosa isolates from various clinical samples from patients admitted to two hospitals located in Rio Grande do Sul, Brazil (twenty-three from a hospital in Porto Alegre City and eight isolates from a hospital in Vale dos Sinos Region. All strains suggestive of possessing MBLs by phenotypic methods were included in this study. Phenotypic detection of MBLs was carried out simultaneously by using both the MBL Etest® and disk approximation test using 2-mercaptopropionic acid close to a ceftazidime disk. Strains positive were further confirmed using molecular techniques for blaVIM, blaIMP and blaSPM-1. The prevalence of MBLs from samplesof inpatients from the hospital located in Porto Alegre was 30.4% and that of inpatients from Vale dos Sinos hospital was only 3.1%. Only MBL type SPM-1 was detected in these samples by molecular analysis and all were detected by the Etest® MBL strips. The prevalence of P. aeruginosa that produce MBLs can be markedly different in distinct geographical areas, even among different hospitals in the same area. In our study, the EDTA-based method was the only method able to detect all strains harboring the SPM-1 enzyme.

  18. Characterizing the citrus cultivar Carrizo genome through 454 shotgun sequencing.

    Science.gov (United States)

    Belknap, William R; Wang, Yi; Huo, Naxin; Wu, Jiajie; Rockhold, David R; Gu, Yong Q; Stover, Ed

    2011-12-01

    The citrus cultivar Carrizo is the single most important rootstock to the US citrus industry and has resistance or tolerance to a number of major citrus diseases, including citrus tristeza virus, foot rot, and Huanglongbing (HLB, citrus greening). A Carrizo genomic sequence database providing approximately 3.5×genome coverage (haploid genome size approximately 367 Mb) was populated through 454 GS FLX shotgun sequencing. Analysis of the repetitive DNA fraction indicated a total interspersed repeat fraction of 36.5%. Assembly and characterization of abundant citrus Ty3/gypsy elements revealed a novel type of element containing open reading frames encoding a viral RNA-silencing suppressor protein (RNA binding protein, rbp) and a plant cytokinin riboside 5′-monophosphate phosphoribohydrolase-related protein (LONELY GUY, log). Similar gypsy elements were identified in the Populus trichocarpa genome. Gene-coding region analysis indicated that 24.4% of the nonrepetitive reads contained genic regions. The depth of genome coverage was sufficient to allow accurate assembly of constituent genes, including a putative phloem-expressed gene. The development of the Carrizo database (http://citrus.pw.usda.gov/) will contribute to characterization of agronomically significant loci and provide a publicly available genomic resource to the citrus research community.

  19. A simple multiplex PCR for assessing prevalence of extended-spectrumβ-lactamases producing Klebsiella pneumoniae in Intensive Care Units of a referral hospital in Shiraz, Iran

    Institute of Scientific and Technical Information of China (English)

    Younes Ghasemi; Talieh Archin; Mohammad Kargar; Milad Mohkam

    2013-01-01

    Objective:To identify three common genes (blaTEM, blaSHV and blaCTX-M) responsible for ESBL production in Klebsiella pneumoniae (K. pneumoniae) isolated from Intensive Care Units of Namazi Hospital, Shiraz, Iran. Methods:A total of 60 non-repetitive nosocomial isolates from 60 patients were selected during 2009-2010. The phenotypic identification of ESBL production was confirmed by Double Disk Synergy Test (DDST) according to CLSI guidelines. The ESBL’s genotype was then analyzed by multiplex PCR of blaTEM, blaSHV and blaCTX-M genes and DNA sequencing. Results: The primary susceptibility tests of K. pneumoniae showed that among 10 examined antibiotics, the most resistant and susceptible antibiotics identified in this study were ampicillin and imipenem, respectively. The phenotypic determination of ESBL by DDST showed that 60%(n=36) of isolates produced ESBL. Multiplex PCR of genes among K. pneumoniae isolates showed that 39% (n=18) of them have TEM, 39% (n=18) of them have both CTX-M and TEM and 13% (n=8) of them have TEM, SHV, CTX-M. Conclusions:Our findings reveal the high prevalence (60%) of ESBL producing K. pneumoniae from ICU patients along with a new pattern of blaTEM distribution differ from other countries.

  20. Metallo-β-lactamase-producing Pseudomonas aeruginosa in two hospitals from southern Brazil

    Directory of Open Access Journals (Sweden)

    Fernanda W. Wirth

    Full Text Available This study determined the prevalence of metallo-β-lactamase (MBL-producing Pseudomonas aeruginosa in two hospitals located in the Southern part of Brazil and compare the performance of two different phenotypic tests. Thirty-one non-repetitive Pseudomonas aeruginosa isolates from various clinical samples from patients admitted to two hospitals located in Rio Grande do Sul, Brazil (twenty-three from a hospital in Porto Alegre City and eight isolates from a hospital in Vale dos Sinos Region. All strains suggestive of possessing MBLs by phenotypic methods were included in this study. Phenotypic detection of MBLs was carried out simultaneously by using both the MBL Etest® and disk approximation test using 2-mercaptopropionic acid close to a ceftazidime disk. Strains positive were further confirmed using molecular techniques for blaVIM, blaIMP and blaSPM-1. The prevalence of MBLs from samplesof inpatients from the hospital located in Porto Alegre was 30.4% and that of inpatients from Vale dos Sinos hospital was only 3.1%. Only MBL type SPM-1 was detected in these samples by molecular analysis and all were detected by the Etest® MBL strips. The prevalence of P. aeruginosa that produce MBLs can be markedly different in distinct geographical areas, even among different hospitals in the same area. In our study, the EDTA-based method was the only method able to detect all strains harboring the SPM-1 enzyme.

  1. NMR and MS evidences for a random assembled O-specific chain structure in the LPS of the bacterium Xanthomonas campestris pv. Vitians. A case of unsystematic biosynthetic polymerization.

    Science.gov (United States)

    Molinaro, Antonio; De Castro, Cristina; Lanzetta, Rosa; Parrilli, Michelangelo; Petersen, Bent O; Broberg, Anders; Duus, Jens Ø

    2002-09-01

    Xanthomonas campestris pv. vitians is a Gram-negative plant-associated bacterium that acts as causative agent of bacterial leaf spot and headrot in lettuce. The lipopolysaccharide of this bacterium is suspected to be an important molecule for adhesion to and infection of the plants. The lipopolysaccharide has been isolated from the phenol phase and the O-specific chain characterized by compositional analysis, high field NMR and MALDI-TOF MS. It consists of a nonrepetitive branched polysaccharide with a rhamnan backbone to which Fuc3NAc is linked. The NMR and MS approach led to the characterization of the fine structure of the polymer, which is randomly assembled. The rhamnan backbone is built up of beta-Rhap and alpha-Rhap, this last is present in one, two or three adjacent units and branched by an alpha-Fucp3NAc unit. This is a real case of a random constituted O-specific chain, therefore biosynthetic studies towards the comprehension of this irregular biosynthesis are needed.

  2. fMRI repetition suppression: neuronal adaptation or stimulus expectation?

    Science.gov (United States)

    Larsson, Jonas; Smith, Andrew T

    2012-03-01

    Measurements of repetition suppression with functional magnetic resonance imaging (fMRI adaptation) have been used widely to probe neuronal population response properties in human cerebral cortex. fMRI adaptation techniques assume that fMRI repetition suppression reflects neuronal adaptation, an assumption that has been challenged on the basis of evidence that repetition-related response changes may reflect unrelated factors, such as attention and stimulus expectation. Specifically, Summerfield et al. (Summerfield C, Trittschuh EH, Monti JM, Mesulam MM, Egner T. 2008. Neural repetition suppression reflects fulfilled perceptual expectations. Nat Neurosci. 11:1004-1006) reported that the relative frequency of stimulus repetitions and non-repetitions influenced the magnitude of repetition suppression in the fusiform face area, suggesting that stimulus expectation accounted for most of the effect of repetition. We confirm that stimulus expectation can significantly influence fMRI repetition suppression throughout visual cortex and show that it occurs with long as well as short adaptation durations. However, the effect was attention dependent: When attention was diverted away from the stimuli, the effects of stimulus expectation completely disappeared. Nonetheless, robust and significant repetition suppression was still evident. These results suggest that fMRI repetition suppression reflects a combination of neuronal adaptation and attention-dependent expectation effects that can be experimentally dissociated. This implies that with an appropriate experimental design, fMRI adaptation can provide valid measures of neuronal adaptation and hence response specificity.

  3. New insight into the mechanism underlying fibroin secretion in silkworm, Bombyx mori.

    Science.gov (United States)

    Long, Dingpei; Lu, Weijian; Zhang, Yang; Guo, Qing; Xiang, Zhonghuai; Zhao, Aichun

    2015-01-01

    In order to investigate the role of different parts of the fibroin heavy chain (H-chain) in the secretion of fibroin in the silk gland of the silkworm (Bombyx mori) in vivo, two enhanced green fluorescent protein (EGFP)/H-chain fusion genes with deduced protein sequences containing an identical N-terminal region and different C-terminal regions of the H-chain were introduced into the B. mori genome using a piggyBac-mediated germline transformation. EGFP fluorescence and molecular analysis showed the products of two different EGFP/H-chain fusion proteins were secreted into the posterior silk gland lumen and aggregated in the middle silk gland and spun into cocoons. The results revealed that only the non-repetitive N terminus of the H-chain is essential for secretion of the H-chain into the posterior silk gland lumen. In addition, our results also indicated that the most likely post-translational modification of the H-chain is at the C-terminal domain. Here, our results not only provide a theoretical basis for the genetic modification of silk fiber as a functional biomaterial but also are of great significance to establishing a new silk gland bioreactor to mass-produce exogenous proteins in an active form.

  4. Intergenic and repeat transcription in human, chimpanzee and macaque brains measured by RNA-Seq.

    Directory of Open Access Journals (Sweden)

    Augix Guohua Xu

    Full Text Available Transcription is the first step connecting genetic information with an organism's phenotype. While expression of annotated genes in the human brain has been characterized extensively, our knowledge about the scope and the conservation of transcripts located outside of the known genes' boundaries is limited. Here, we use high-throughput transcriptome sequencing (RNA-Seq to characterize the total non-ribosomal transcriptome of human, chimpanzee, and rhesus macaque brain. In all species, only 20-28% of non-ribosomal transcripts correspond to annotated exons and 20-23% to introns. By contrast, transcripts originating within intronic and intergenic repetitive sequences constitute 40-48% of the total brain transcriptome. Notably, some repeat families show elevated transcription. In non-repetitive intergenic regions, we identify and characterize 1,093 distinct regions highly expressed in the human brain. These regions are conserved at the RNA expression level across primates studied and at the DNA sequence level across mammals. A large proportion of these transcripts (20% represents 3'UTR extensions of known genes and may play roles in alternative microRNA-directed regulation. Finally, we show that while transcriptome divergence between species increases with evolutionary time, intergenic transcripts show more expression differences among species and exons show less. Our results show that many yet uncharacterized evolutionary conserved transcripts exist in the human brain. Some of these transcripts may play roles in transcriptional regulation and contribute to evolution of human-specific phenotypic traits.

  5. Ultrafast measurements of optical spectral coherence by single-shot time-stretch interferometry

    Science.gov (United States)

    Xu, Yiqing; Wei, Xiaoming; Ren, Zhibo; Wong, Kenneth K. Y.; Tsia, Kevin K.

    2016-06-01

    The palette of laser technology has significantly been enriched by the innovations in ultrafast optical pulse generation. Our knowledge of the complex pulse dynamics, which is often highly nonlinear and stochastic in nature, is however limited by the scarcity of technologies that can measure fast variation/fluctuation of the spectral phase (or coherence) and amplitude in real-time, continuously. To achieve this goal, we demonstrate ultrafast interferometry enabled by optical time-stretch for real- time spectral coherence characterization with microsecond-resolution. Accessing the single-shot interferograms continuously, it further reveals the degree of second-order coherence, defined by the cross-spectral density function, at high speed-a capability absent in any existing spectroscopic measurement tools. As the technique can simultaneously measure both the high-speed variations of spectrally resolved coherence and intensity, time-stretch interferometry could create a new arena for ultrafast pulse characterization, especially favorable for probing and understanding the non-repetitive or stochastic dynamics in real-time.

  6. A DNA sequence evolution analysis generalized by simulation and the markov chain monte carlo method implicates strand slippage in a majority of insertions and deletions.

    Science.gov (United States)

    Nishizawa, Manami; Nishizawa, Kazuhisa

    2002-12-01

    To study the mechanisms for local evolutionary changes in DNA sequences involving slippage-type insertions and deletions, an alignment approach is explored that can consider the posterior probabilities of alignment models. Various patterns of insertion and deletion that can link the ancestor and descendant sequences are proposed and evaluated by simulation and compared by the Markov chain Monte Carlo (MCMC) method. Analyses of pseudogenes reveal that the introduction of the parameters that control the probability of slippage-type events markedly augments the probability of the observed sequence evolution, arguing that a cryptic involvement of slippage occurrences is manifested as insertions and deletions of short nucleotide segments. Strikingly, approximately 80% of insertions in human pseudogenes and approximately 50% of insertions in murids pseudogenes are likely to be caused by the slippage-mediated process, as represented by BC in ABCD --> ABCBCD. We suggest that, in both human and murids, even very short repetitive motifs, such as CAGCAG, CACACA, and CCCC, have approximately 10- to 15-fold susceptibility to insertions and deletions, compared to nonrepetitive sequences. Our protocol, namely, indel-MCMC, thus seems to be a reasonable approach for statistical analyses of the early phase of microsatellite evolution.

  7. Outbreak Caused by blaOXA-72-Producing Acinetobacter baumannii ST417 Detected in Clinical and Environmental Isolates.

    Science.gov (United States)

    Tamayo-Legorreta, Elsa; Turrubiartes-Martínez, Edgar; Garza-Ramos, Ulises; Niño-Moreno, Perla; Barrios, Humberto; Sánchez-Pérez, Alejandro; Reyna-Flores, Fernando; Tovar-Oviedo, Juana; Magaña-Aquino, Martin; Cevallos, Miguel Angel; Silva-Sanchez, Jesus

    2016-03-01

    We characterized an outbreak of imipenem-resistant Acinetobacter baumannii with clinical and environmental isolates from a tertiary care hospital in San Luis Potosi, Mexico. During a 4-month period, a total of 32 nonrepetitive imipenem-resistant clinical isolates of A. baumannii were collected. All isolates were susceptible to colistin and tigecycline and resistant to cefepime, ceftazidime, ceftriaxone, imipenem, and meropenem. Genotyping by pulsed-field gel electrophoresis showed a major clone (A). Multilocus sequence type (MLST) analysis was performed, revealing sequence type (ST) 417 (ST417) and 208 (ST208). The blaIMP-, blaVIM-, blaGIM-, blaSIM-, blaNDM-type, and blaOXA-type (blaOXA-23-like, blaOXA-24-like, blaOXA-51-like, and blaOXA-58-like) genes were screened and showed that the blaOXA-51-like and blaOXA-24-like genes were present in all isolates. Sequencing and southern hybridization were performed, confirming the presence of the blaOXA-72 gene and its plasmid-borne nature. In addition, the blaOXA-72-XerC/XerD-like association was identified. These findings indicate that a clonal spread of blaOXA-72-producing A. baumannii ST417 had occurred throughout the hospital. The ST417 corresponded with a previous ST described in the United States.

  8. User's guide for the REBUS-3 fuel cycle analysis capability

    Energy Technology Data Exchange (ETDEWEB)

    Toppel, B.J.

    1983-03-01

    REBUS-3 is a system of programs designed for the fuel-cycle analysis of fast reactors. This new capability is an extension and refinement of the REBUS-3 code system and complies with the standard code practices and interface dataset specifications of the Committee on Computer Code Coordination (CCCC). The new code is hence divorced from the earlier ARC System. In addition, the coding has been designed to enhance code exportability. Major new capabilities not available in the REBUS-2 code system include a search on burn cycle time to achieve a specified value for the multiplication constant at the end of the burn step; a general non-repetitive fuel-management capability including temporary out-of-core fuel storage, loading of fresh fuel, and subsequent retrieval and reloading of fuel; significantly expanded user input checking; expanded output edits; provision of prestored burnup chains to simplify user input; option of fixed-or free-field BCD input formats; and, choice of finite difference, nodal or spatial flux-synthesis neutronics in one-, two-, or three-dimensions.

  9. The Perception of Symmetry in Depth: Effect of Symmetry Plane Orientation

    Directory of Open Access Journals (Sweden)

    Bart Farell

    2015-04-01

    Full Text Available The visual system is sensitive to symmetries in the frontoparallel plane, and bilateral symmetry about a vertical axis has a particular salience. However, these symmetries represent only a subset of the symmetries realizable in three-dimensional space. The retinal image symmetries formed when viewing natural objects are typically the projections of three-dimensional objects—animals, for example—that have a symmetry in depth. To characterize human sensitivity to depth symmetry, experiments measured observers’ ability to discriminate stereo displays that were symmetrically distributed in depth and those that were asymmetrically distributed. Disparity values were distributed about one of four planes passing through the z-axis and differing in frontoparallel orientation. Asymmetrical patterns were generated by perturbing one of these disparities. Symmetrical-asymmetrical discrimination thresholds were lowest for symmetry about the vertical plane and highest for the horizontal plane. Thresholds for discriminating repetitions and non-repetitions of depth values did not differ across the four planes, whereas discriminations for depth gradients differed from both the symmetry and repetition cases. The heightened sensitivity to symmetry in depth about the vertical plane is a 3-D analog of 2-D mirror-image symmetry performance and could be its source.

  10. Concomitant detection of biofilm and metallo-beta-lactamases production in gram-negative bacilli

    Directory of Open Access Journals (Sweden)

    Monil Singhai

    2013-01-01

    Full Text Available Carbapenems are mainstay of treating serious multidrug resistant gram-negative biofilm-based infections. However, recent emergence of metallo-beta-lactamases (MbL producing gram-negative bacilli in different parts of world may be related to gain of virulence factors associated with biofilm production. Objectives: To explore the association of MbL and biofilm production in various gram-negative bacilli. Materials and Methods: In this study, 110 non-repetitive ceftazidime resistant gram-negative bacilli were evaluated for biofilm and MβL production. Biofilm forming ability of isolates obtained from various specimens was tested by the tube method. Disks of ceftazidime (30 μg and ceftazidime with ethylenediaminetetraacetic acid (30 μg + 750 μg, prepared in house for MβL detection were used. Chi-square test was used to study the association between biofilm and MβL production. P value <0.05 was considered significant. Results: 88 (80% bacilli had shown biofilm producing ability. The association of biofilm and MβL was significant in cases of non-fermenters as compared to enterobacteriaceae members. Conclusion: The particular combination of virulence factors (biofilm and MβL in bacteria may be a species specific effect which needs to be investigated at molecular level in detail. This may help in designing newer therapies based on interference with biofilm formation and thus countering clinical episodes of antibiotic resistance.

  11. Genbit Compress Tool(GBC): A Java-Based Tool to Compress DNA Sequences and Compute Compression Ratio(bits/base) of Genomes

    CERN Document Server

    Rajeswari, P Raja; Kumar, V K; 10.5121/ijcsit.2010.2313

    2010-01-01

    We present a Compression Tool, "GenBit Compress", for genetic sequences based on our new proposed "GenBit Compress Algorithm". Our Tool achieves the best compression ratios for Entire Genome (DNA sequences) . Significantly better compression results show that GenBit compress algorithm is the best among the remaining Genome compression algorithms for non-repetitive DNA sequences in Genomes. The standard Compression algorithms such as gzip or compress cannot compress DNA sequences but only expand them in size. In this paper we consider the problem of DNA compression. It is well known that one of the main features of DNA Sequences is that they contain substrings which are duplicated except for a few random Mutations. For this reason most DNA compressors work by searching and encoding approximate repeats. We depart from this strategy by searching and encoding only exact repeats. our proposed algorithm achieves the best compression ratio for DNA sequences for larger genome. As long as 8 lakh characters can be give...

  12. Molecular Characteristics and Antibiotic Resistance Profiles of Klebsiella Isolates in Mthatha, Eastern Cape Province, South Africa

    Directory of Open Access Journals (Sweden)

    Sandeep Vasaikar

    2017-01-01

    Full Text Available The increase in the incidence of extended-spectrum β-lactamase- (ESBL- producing Klebsiella species has become a serious problem worldwide, because of their incrimination in antibiotic resistance. The objective of this study is to investigate the resistance genes responsible for ESBL-producing Klebsiella species and carbapenemase-producing Klebsiella (CRE isolated in Mthatha and to study their epidemiology. A prospective, descriptive study of 202 nonrepetitive samples from patients was obtained from Nelson Mandela Academic Hospital. The cultured Klebsiella isolates were subjected to antimicrobial susceptibility tests and the polymerase chain reaction of blaCTX-M, blaTEM, blaSHV, blaKPC, and blaNDM genes. Overall K. pneumoniae were the majority with 169 (83.7% species isolates, followed by K. oxytoca with 29 (14.4%, while K. ozaenae and Raoultella ornithinolytica were 2 (0.9% each. The prevalence of ESBL production in all Klebsiella species was 117 (57.9%. ESBL-genotypic resistance is driven in Mthatha by blaSHV 121 (77.1% followed by blaTEM 105 (66.9% and blaCTX-M at 89 (56.7%. The most common ESBL genotype combination among the Klebsiella was blaTEM+blaSHV + blaCTX-M at 79 (50.3%. There is a steady increase in the rate of ESBL genes in the last five years.

  13. Identiifcation of a Group of Novel γ-Gliadin Genes

    Institute of Scientific and Technical Information of China (English)

    QI Peng-fei; WEI Yu-ming; Ouellet Thrse; CHEN Qing; WANG Zhao; WEI Zhen-zhen; ZHENG You-liang

    2014-01-01

    γ-Gliadins are an important component of wheat seed storage proteins. Four novel γ-gliadin genes (Gli-ng1 toGli-ng4) were cloned from wheat (Triticum aestivum) andAegilops species. The novel γ-gliadins were much smaller in molecular size when compared to the typical γ-gliadins, which was caused by deletion of the non-repetitive domain, glutamine-rich region, 3´ part of the repetitive domain, and 5´ part of the C-terminal, possibly due to illegitimate recombination between the repetitive domain and the C-terminal. As a result,Gli-ng1 andGli-ng4 only contained two and three cysteine residues, respectively. Gli-ng1, as the representative of novel γ-gliadin genes, has been sub-cloned into anEscherichia coli expression system. SDS-PAGE indicated that the both cysteine residues ofGli-ng1 could participate in the formation of intermolecular disulphide bondsin vitro. Successful cloning ofGli-ng1 from seed cDNA ofT. aestivumcv. Chinese Spring suggested that these novel γ-gliadin genes were normally transcribed during the development of seeds. Phylogenic analysis indicated that the four novel γ-gliadin genes had a closer relationship with those from the B (S) genome of wheat.

  14. Molecular cloning and expression of the C-terminus of spider flagelliform silk protein from Araneus ventricosus

    Indian Academy of Sciences (India)

    Kwang Sik Lee; Bo Yeon Kim; Yeon Ho Je; Soo Dong Woo; Hung Dae Sohn; Byung Rae Jin

    2007-06-01

    A cDNA coding for the C-terminus of spider flagelliform silk protein (AvFlag) was cloned from Araneus ventricosus. Analysis of the cDNA sequence shows that the C-terminus of AvFlag consists of 167 amino acids of a repetitive region and 87 amino acids of a C-terminal non-repetitive region. The peptide motifs found in spider flagelliform silk proteins, GPGGX and GGX, were conserved in the repetitive region of AvFlag. Phylogenetic analysis further confirmed that AvFlag belongs to the spider flagelliform silk proteins. The AvFlag cDNA was expressed as a 28 kDa polypeptide in baculovirus-infected insect cells. As a new expression approach for spider silk protein, the combination of polyhedrin and AvFlag creates a polyhedrin AvFlag fusion protein (61 kDa) that is produced as recombinant polyhedra; this provides a basis for the source of spider silk proteins for various applications.

  15. Magnitude of enterococcal bacteremia in trauma patients admitted for intensive trauma care: A tertiary care experience from South Asian country

    Directory of Open Access Journals (Sweden)

    Nonika Rajkumari

    2015-01-01

    Full Text Available Background: Bloodstream infection (BSI and bacteremias due to Enterococcus spp. are increasing worldwide with the current need to understand its causes among hospitalized trauma patients. Hence, the study was conducted. Methodology: A 3-year retrospective laboratory cum clinical based study was performed at a level I trauma center in India. Patients with health care associated enterococcal bacteremia were identified using the hospital database, their episodes of BSI/bacteremia calculated and their clinical records and treatment were noted. Results: A total of 104 nonrepetitive Enterococcus spp. was isolated of which Enterococcus faecium was the most common (52%. High-level resistance to gentamicin high-level aminoglycoside resistance was seen in all the Enterococcus spp. causing bacteremia, whereas a low resistance to vancomycin and teichoplanin was observed. Overall mortality was more in patients infected with vancomycin-resistant Enterococcus (5/11, 46% compared to those with vancomycin sensitive Enterococcus (9/93, 10%; though no significant association of mortality with Enterococcus spp. bacteremia ( P > 0.05 was seen. The rate of bacteremia due to Enterococcus spp. was 25.4 episodes/1,000 admissions (104/4,094 during the study period. Conclusion: Enterococcal bacteremia is much prevalent in trauma care facilities. Here, a microbiologist can act as a sentinel and help in preventing such infections.

  16. Clustered regularly interspaced short palindromic repeats (CRISPRs) analysis of members of the Mycobacterium tuberculosis complex.

    Science.gov (United States)

    Botelho, Ana; Canto, Ana; Leão, Célia; Cunha, Mónica V

    2015-01-01

    Typical CRISPR (clustered, regularly interspaced, short palindromic repeat) regions are constituted by short direct repeats (DRs), interspersed with similarly sized non-repetitive spacers, derived from transmissible genetic elements, acquired when the cell is challenged with foreign DNA. The analysis of the structure, in number and nature, of CRISPR spacers is a valuable tool for molecular typing since these loci are polymorphic among strains, originating characteristic signatures. The existence of CRISPR structures in the genome of the members of Mycobacterium tuberculosis complex (MTBC) enabled the development of a genotyping method, based on the analysis of the presence or absence of 43 oligonucleotide spacers separated by conserved DRs. This method, called spoligotyping, consists on PCR amplification of the DR chromosomal region and recognition after hybridization of the spacers that are present. The workflow beneath this methodology implies that the PCR products are brought onto a membrane containing synthetic oligonucleotides that have complementary sequences to the spacer sequences. Lack of hybridization of the PCR products to a specific oligonucleotide sequence indicates absence of the correspondent spacer sequence in the examined strain. Spoligotyping gained great notoriety as a robust identification and typing tool for members of MTBC, enabling multiple epidemiological studies on human and animal tuberculosis.

  17. An ERP study of inhibition of non-target languages in trilingual word production.

    Science.gov (United States)

    Guo, Taomei; Ma, Fengyang; Liu, Fengqin

    2013-10-01

    The present study examined the locus where inhibition of non-target languages is exerted during trilingual word production by analyzing the cue-locked and stimulus-locked ERPs respectively in the n-2 language repetition paradigm. During the experiment, Uighur-Chinese-English trilinguals overtly named Arabic digits in one of their three languages according to a visually presented cue while their behavioral and electrophysiological responses were recorded. The behavioral data revealed insignificant n-2 repetition costs. Cue-locked ERPs revealed also only tiny or marginally significant n-2 repetition effects over some midline electrodes. The stimulus-locked ERP data showed a more negative ERP component elicited by the n-2 repetition trials than the n-2 non-repetition trials around 250 ms after stimulus onset, but no significant difference in this ERP effect between different languages was found. The results indicate that inhibition of non-target languages occurs at the lemma selection phase rather than the language task schemas phase during trilingual language production.

  18. Predominance of Three Closely Related Methicillin-Resistant Staphylococcus aureus Clones Carrying a Unique ccrC-Positive SCCmec type III and the Emergence of spa t304 and t690 SCCmec type IV pvl(+) MRSA Isolates in Kinta Valley, Malaysia.

    Science.gov (United States)

    Ho, Wai-Yew; Choo, Quok-Cheong; Chew, Choy-Hoong

    2017-03-01

    We investigated the epidemiology and clonality of 175 nonrepetitive methicillin-resistant Staphylococcus aureus (MRSA) isolates from clinical specimens collected between 2011 and 2012 in Kinta Valley in Malaysia. Molecular tools such as polymerase chain reaction, pulsed-field gel electrophoresis, and staphylococcal protein A (spa) typing were used. Our study revealed the predominance of three closely related ermA(+) SCCmec type III pulsotypes belonging to spa type t037 (Brazilian-Hungarian clone), which were deficient in the locus F, but positive for the ccrC gene in majority (65.7%) of the MRSA infections in this region. The first evidence of SCCmec type II MRSA in the country, belonging to spa type t2460, was also noted. Although the carriage of pvl gene was uncommon (8.6%) and mostly confined to either SCCmec type IV or SCCmec type V isolates, most of these isolates belonged to spa types t345 or t657, which are associated with the Bengal-Bay CA-MRSA clone. Interestingly, spa t304 and t690 SCCmec type IV pvl(+) were also detected among the MRSA isolates. Data from this study show the rise of uncommon clones among MRSA isolates in Malaysia.

  19. Carbonic anhydrase generates CO2 and H+ that drive spider silk formation via opposite effects on the terminal domains.

    Science.gov (United States)

    Andersson, Marlene; Chen, Gefei; Otikovs, Martins; Landreh, Michael; Nordling, Kerstin; Kronqvist, Nina; Westermark, Per; Jörnvall, Hans; Knight, Stefan; Ridderstråle, Yvonne; Holm, Lena; Meng, Qing; Jaudzems, Kristaps; Chesler, Mitchell; Johansson, Jan; Rising, Anna

    2014-08-01

    Spider silk fibers are produced from soluble proteins (spidroins) under ambient conditions in a complex but poorly understood process. Spidroins are highly repetitive in sequence but capped by nonrepetitive N- and C-terminal domains (NT and CT) that are suggested to regulate fiber conversion in similar manners. By using ion selective microelectrodes we found that the pH gradient in the silk gland is much broader than previously known. Surprisingly, the terminal domains respond in opposite ways when pH is decreased from 7 to 5: Urea denaturation and temperature stability assays show that NT dimers get significantly stabilized and then lock the spidroins into multimers, whereas CT on the other hand is destabilized and unfolds into ThT-positive β-sheet amyloid fibrils, which can trigger fiber formation. There is a high carbon dioxide pressure (pCO2) in distal parts of the gland, and a CO2 analogue interacts with buried regions in CT as determined by nuclear magnetic resonance (NMR) spectroscopy. Activity staining of histological sections and inhibition experiments reveal that the pH gradient is created by carbonic anhydrase. Carbonic anhydrase activity emerges in the same region of the gland as the opposite effects on NT and CT stability occur. These synchronous events suggest a novel CO2 and proton-dependent lock and trigger mechanism of spider silk formation.

  20. Carbonic anhydrase generates CO2 and H+ that drive spider silk formation via opposite effects on the terminal domains.

    Directory of Open Access Journals (Sweden)

    Marlene Andersson

    2014-08-01

    Full Text Available Spider silk fibers are produced from soluble proteins (spidroins under ambient conditions in a complex but poorly understood process. Spidroins are highly repetitive in sequence but capped by nonrepetitive N- and C-terminal domains (NT and CT that are suggested to regulate fiber conversion in similar manners. By using ion selective microelectrodes we found that the pH gradient in the silk gland is much broader than previously known. Surprisingly, the terminal domains respond in opposite ways when pH is decreased from 7 to 5: Urea denaturation and temperature stability assays show that NT dimers get significantly stabilized and then lock the spidroins into multimers, whereas CT on the other hand is destabilized and unfolds into ThT-positive β-sheet amyloid fibrils, which can trigger fiber formation. There is a high carbon dioxide pressure (pCO2 in distal parts of the gland, and a CO2 analogue interacts with buried regions in CT as determined by nuclear magnetic resonance (NMR spectroscopy. Activity staining of histological sections and inhibition experiments reveal that the pH gradient is created by carbonic anhydrase. Carbonic anhydrase activity emerges in the same region of the gland as the opposite effects on NT and CT stability occur. These synchronous events suggest a novel CO2 and proton-dependent lock and trigger mechanism of spider silk formation.

  1. Combination of Sharing Matrix and Image Encryption for Lossless $(k,n)$ -Secret Image Sharing.

    Science.gov (United States)

    Bao, Long; Yi, Shuang; Zhou, Yicong

    2017-12-01

    This paper first introduces a (k,n) -sharing matrix S((k, n)) and its generation algorithm. Mathematical analysis is provided to show its potential for secret image sharing. Combining sharing matrix with image encryption, we further propose a lossless (k,n) -secret image sharing scheme (SMIE-SIS). Only with no less than k shares, all the ciphertext information and security key can be reconstructed, which results in a lossless recovery of original information. This can be proved by the correctness and security analysis. Performance evaluation and security analysis demonstrate that the proposed SMIE-SIS with arbitrary settings of k and n has at least five advantages: 1) it is able to fully recover the original image without any distortion; 2) it has much lower pixel expansion than many existing methods; 3) its computation cost is much lower than the polynomial-based secret image sharing methods; 4) it is able to verify and detect a fake share; and 5) even using the same original image with the same initial settings of parameters, every execution of SMIE-SIS is able to generate completely different secret shares that are unpredictable and non-repetitive. This property offers SMIE-SIS a high level of security to withstand many different attacks.

  2. High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects.

    Science.gov (United States)

    Kleinstiver, Benjamin P; Pattanayak, Vikram; Prew, Michelle S; Tsai, Shengdar Q; Nguyen, Nhu T; Zheng, Zongli; Joung, J Keith

    2016-01-28

    CRISPR-Cas9 nucleases are widely used for genome editing but can induce unwanted off-target mutations. Existing strategies for reducing genome-wide off-target effects of the widely used Streptococcus pyogenes Cas9 (SpCas9) are imperfect, possessing only partial or unproven efficacies and other limitations that constrain their use. Here we describe SpCas9-HF1, a high-fidelity variant harbouring alterations designed to reduce non-specific DNA contacts. SpCas9-HF1 retains on-target activities comparable to wild-type SpCas9 with >85% of single-guide RNAs (sgRNAs) tested in human cells. Notably, with sgRNAs targeted to standard non-repetitive sequences, SpCas9-HF1 rendered all or nearly all off-target events undetectable by genome-wide break capture and targeted sequencing methods. Even for atypical, repetitive target sites, the vast majority of off-target mutations induced by wild-type SpCas9 were not detected with SpCas9-HF1. With its exceptional precision, SpCas9-HF1 provides an alternative to wild-type SpCas9 for research and therapeutic applications. More broadly, our results suggest a general strategy for optimizing genome-wide specificities of other CRISPR-RNA-guided nucleases.

  3. An overview of the EtsaTrans machine translation system: compilation of an administrative domain

    Directory of Open Access Journals (Sweden)

    L. Ehlers

    2008-07-01

    Full Text Available The EtsaTrans machine translation system has been in development at the University of the Free State for the last four years and is currently the only machine translation system being developed in South Africa for specialised and nongeneral translation needs. The purpose of this exposition is to present the program through its phases of development, and to report on current levels of performance. We analyse the output, the size of the database, and then propose the future implementation of a part of speech tagger and word stemmer into the program to improve its linguistic performance. Our goal with the system is not to translate all types of document, but to work in a specialised domain that will allow the system to translate documents that are repetitive in nature. This will enable translators to spend more time on non-repetitive subject matter. By capturing the nature of the language of such repetitive documents in the database, we are able to create a standardised language usage for the specialised domain.

  4. New ultrarapid-scanning interferometer for FT-IR spectroscopy with microsecond time-resolution

    Science.gov (United States)

    Süss, B.; Ringleb, F.; Heberle, J.

    2016-06-01

    A novel Fourier-transform infrared (FT-IR) rapid-scan spectrometer has been developed (patent pending EP14194520.4) which yields 1000 times higher time resolution as compared to conventional rapid-scanning spectrometers. The central element to achieve faster scanning rates is based on a sonotrode whose front face represents the movable mirror of the interferometer. A prototype spectrometer with a time resolution of 13 μs was realized, capable of fully automated long-term measurements with a flow cell for liquid samples, here a photosynthetic membrane protein in solution. The performance of this novel spectrometer is demonstrated by recording the photoreaction of bacteriorhodopsin initiated by a short laser pulse that is synchronized to the data recording. The resulting data are critically compared to those obtained by step-scan spectroscopy and demonstrate the relevance of performing experiments on proteins in solution. The spectrometer allows for future investigations of fast, non-repetitive processes, whose investigation is challenging to step-scan FT-IR spectroscopy.

  5. Trends in antimicrobial resistance among clinical isolates of enterococci in a Brazilian tertiary hospital: a 4-year study

    Directory of Open Access Journals (Sweden)

    Natália Conceição

    2011-04-01

    Full Text Available INTRODUCTION: In the past two decades members of the genus Enterococcus have emerged as important nosocomial pathogens worldwide. This study prospectively analyzed the distribution of species and trends in antimicrobial resistance among clinical isolates of enterococci in a Brazilian tertiary hospital from 2006-2009. METHODS: Enterococcal species were identified by conventional biochemical tests. The antimicrobial susceptibility profile was performed by disk diffusion in accordance with the Clinical and Laboratory Standards Institute (CLSI. A screening test for vancomycin was also performed. Minimal inhibitory concentration (MIC for vancomycin was determined using the broth dilution method. Molecular assays were used to confirm speciation and genotype of vancomycin-resistant enterococci (VRE. RESULTS: A total of 324 non-repetitive enterococcal isolates were recovered, of which 87% were E. faecalis and 10.8% E. faecium. The incidence of E. faecium per 1,000 admissions increased significantly (p 256µg/ mL and harbored vanA genes. The majority (89.5% of VRE belonged to E. faecium species, which were characteristically resistant to ampicillin and quinolones. Overall, ampicillin resistance rate increased significantly from 2.5% to 21.4% from 2006-2009. Resistance rates for gentamicin, chloramphenicol, tetracycline, and erythromycin significantly decreased over time, although they remained high. Quinolones resistance rates were high and did not change significantly over time. CONCLUSIONS: The data obtained show a significant increasing trend in the incidence of E. faecium resistant to ampicillin and vancomycin.

  6. ArchDB 2014: structural classification of loops in proteins

    Science.gov (United States)

    Bonet, Jaume; Planas-Iglesias, Joan; Garcia-Garcia, Javier; Marín-López, Manuel A.; Fernandez-Fuentes, Narcis; Oliva, Baldo

    2014-01-01

    The function of a protein is determined by its three-dimensional structure, which is formed by regular (i.e. β-strands and α-helices) and non-periodic structural units such as loops. Compared to regular structural elements, non-periodic, non-repetitive conformational units enclose a much higher degree of variability—raising difficulties in the identification of regularities, and yet represent an important part of the structure of a protein. Indeed, loops often play a pivotal role in the function of a protein and different aspects of protein folding and dynamics. Therefore, the structural classification of protein loops is an important subject with clear applications in homology modelling, protein structure prediction, protein design (e.g. enzyme design and catalytic loops) and function prediction. ArchDB, the database presented here (freely available at http://sbi.imim.es/archdb), represents such a resource and has been an important asset for the scientific community throughout the years. In this article, we present a completely reworked and updated version of ArchDB. The new version of ArchDB features a novel, fast and user-friendly web-based interface, and a novel graph-based, computationally efficient, clustering algorithm. The current version of ArchDB classifies 149,134 loops in 5739 classes and 9608 subclasses. PMID:24265221

  7. Complete mitochondrial genome of the atlas moth, Attacus atlas (Lepidoptera: Saturniidae) and the phylogenetic relationship of Saturniidae species.

    Science.gov (United States)

    Chen, Miao-Miao; Li, Yan; Chen, Mo; Wang, Huan; Li, Qun; Xia, Run-Xi; Zeng, Cai-Yun; Li, Yu-Ping; Liu, Yan-Qun; Qin, Li

    2014-07-15

    Mitochondrial genome (mitogenome) can provide information for genomic structure as well as for phylogenetic analysis and evolutionary biology. In this study, we present the complete mitogenome of the atlas moth, Attacus atlas (Lepidoptera: Saturniidae), a well-known silk-producing and ornamental insect with the largest wing surface area of all moths. The mitogenome of A. atlas is a circular molecule of 15,282 bp long, and its nucleotide composition shows heavily biased towards As and Ts, accounting for 79.30%. This genome comprises 13 protein-coding genes (PCGs), two ribosomal RNA genes (rRNAs), 22 transfer RNA genes (tRNAs), and an A+T-rich region. It is of note that this genome exhibits a slightly positive AT skew, which is different from the other known Saturniidae species. All PCGs are initiated by ATN codons, except for COI with CGA instead. Only six PCGs use a common stop codon of TAA or TAG, whereas the remaining seven use an incomplete termination codon T or TA. All tRNAs have the typical clover-leaf structure, with an exception for tRNA(Ser)(AGN). The A. atlas A+T-rich region contains non-repetitive sequences, but harbors several features common to the Bombycoidea insects. The phylogenetic relationships based on Maximum Likelihood method provide a well-supported outline of Saturniidae, which is in accordance with the traditional morphological classification and recent molecular works.

  8. Quantification of the vocal folds’ dynamic displacements

    Science.gov (United States)

    del Socorro Hernández-Montes, María; Muñoz, Silvino; De La Torre, Manuel; Flores, Mauricio; Pérez, Carlos; Mendoza-Santoyo, Fernando

    2016-05-01

    Fast dynamic data acquisition techniques are required to investigate the motional behavior of the vocal folds (VFs) when they are subjected to a steady air-flow through the trachea. High-speed digital holographic interferometry (DHI) is a non-invasive full-field-of-view technique that has proved its usefulness to study rapid and non-repetitive object movements. Hence it is an ideal technique used here to measure VF displacements and vibration patterns at 2000 fps. Analyses from a set of 200 displacement images showed that VFs’ vibration cycles are established along their width (y) and length (x). Furthermore, the maximum deformation for the right and left VFs’ area may be quantified from these images, which in itself represents an important result in the characterization of this structure. At a controlled air pressure, VF displacements fall within the range ~100-1740 nm, with a calculated precision and accuracy that yields a variation coefficient of 1.91%. High-speed acquisition of full-field images of VFs and their displacement quantification are on their own significant data in the study of their functional and physiological behavior since voice quality and production depend on how they vibrate, i.e. their displacement amplitude and frequency. Additionally, the use of high speed DHI avoids prolonged examinations and represents a significant scientific and technological alternative contribution in advancing the knowledge and working mechanisms of these tissues.

  9. Antimicrobial susceptibility patterns among Escherichia coli urinary isolates from community-onset health care-associated urinary tract infection.

    Science.gov (United States)

    Huang, Ling-Fu; Lo, Yi-Chu; Su, Lin-Hui; Chang, Chin-Lu

    2014-12-01

    Urinary tract infection (UTI) is traditionally classified as community-acquired (CA) and hospital-acquired (HA). Community-onset health care-associated (HCA) infection is a new category that has gained increasing attention. The study aimed to compare the disk susceptibility of nonrepetitive Escherichia coli urinary isolates from HCA-UTI (n = 100) with that of E. coli isolates from CA-UTI (n = 85) and HA-UTI (n = 106). We found that the susceptibility pattern of HCA-UTI E. coli isolates was similar to that of HA-UTI E. coli isolates, but significantly different from that of CA-UTI E. coli isolates. In particular, the proportion of extended-spectrum β-lactamase-producing isolates was significantly higher in HCA-UTI than that in CA-UTI (30.0% vs. 3.5%, p < 0.001). We recommend that when treating HCA-UTI, it is necessary to take urine cultures for susceptibility testing to guide definite antibiotic therapy. Copyright © 2014. Published by Elsevier B.V.

  10. Staphylococcal cassette chromosome mec typing and mecA sequencing in methicillin-resistant staphylococci from Algeria: a highly diversified element with new mutations in mecA.

    Science.gov (United States)

    Djoudi, Ferhat; Bonura, Celestino; Touati, Abdelaziz; Aléo, Aurora; Benallaoua, Said; Mammina, Caterina

    2016-11-01

    Genetic mechanisms of methicillin resistance are still relevant in staphylococci. The aims of this study are to assess the possible exchanges of staphylococcal cassette chromosome mec (SCCmec) among isolates of methicillin-resistant staphylococci (MRS) and to check for known or new mutations in mecA DNA. A total of 35 MRS non-repetitive isolates were recovered, including 20 Staphylococcushaemolyticus, 7 Staphylococcusaureus, 4 Staphylococcussciuri, 2 Staphylococcussaprophyticus and 1 isolate each of Staphylococcusxylosus and Staphylococcuslentus. Only 16 of the 35 strains were assigned to known SCCmec types: 7 SCCmec VII, 6 SCCmec IV and 3 SCCmec III, with possible horizontal transfer of the SCCmec VII from methicillin-resistant S. haemolyticus to methicillin-susceptible S. aureus. mecA gene sequencing in ten selected isolates allowed description of nine punctual mutations, seven of which were reported for the first time. The most frequent mutation was G246E, identified in isolates of methicillin-resistant S. aureus, S. sciuri, S. saprophyticus and S. lentus. These results emphasized the high degree of genetic diversity of SCCmec element in MRS and describe new missense mutations in mecA, which might be important in understanding the evolution of methicillin and new β-lactam resistance.

  11. Efficiency of gate control in double-interdigitated (TIL) GTO thyristors

    Science.gov (United States)

    Silard, A. P.

    1986-04-01

    The research reported in this work was focused on the efficiency of gate control during turn-off in the recently developed double-interdigitated (TIL) GTO thyristors. The 8 mm 2 area, TO-220 packaged, high voltage test devices were investigated under both current and voltage input conditions. The main monitored parameters were: the peak turn-off gain Koff(max), the components of the turn-off time and the gate pulse width tgr. During the tests the TIL GTOs were driven up to an anode current iT = 50 A, a value equal to the non-repetitive peak on-state current ( ITSM) of these thyristors. The performed investigations have shown that these novel GTO devices possess a good efficiency of gate control expressed by: 1) low power consumption by the gate under both current and voltage drive conditions; 2) extremely high turn-off gain Koff(max), which is an increasing function of the anode current in a wide range of gate signals amplitudes and durations; 3) fast turn-off of large amounts of anode current with relatively short gate pulse widths; 4) substantial reduction of the storage time ts and fall time tf through adequate current or voltage drive. Design/behavioral details are given, which are useful in the implementation of the TIL concept in GTOs and other power switching devices, such as the bipolar transistors.

  12. Measuring the circular motion of small objects using laser stroboscopic images.

    Science.gov (United States)

    Wang, Hairong; Fu, Y; Du, R

    2008-01-01

    Measuring the circular motion of a small object, including its displacement, speed, and acceleration, is a challenging task. This paper presents a new method for measuring repetitive and/or nonrepetitive, constant speed and/or variable speed circular motion using laser stroboscopic images. Under stroboscopic illumination, each image taken by an ordinary camera records multioutlines of an object in motion; hence, processing the stroboscopic image will be able to extract the motion information. We built an experiment apparatus consisting of a laser as the light source, a stereomicroscope to magnify the image, and a normal complementary metal oxide semiconductor camera to record the image. As the object is in motion, the stroboscopic illumination generates a speckle pattern on the object that can be recorded by the camera and analyzed by a computer. Experimental results indicate that the stroboscopic imaging is stable under various conditions. Moreover, the characteristics of the motion, including the displacement, the velocity, and the acceleration can be calculated based on the width of speckle marks, the illumination intensity, the duty cycle, and the sampling frequency. Compared with the popular high-speed camera method, the presented method may achieve the same measuring accuracy, but with much reduced cost and complexity.

  13. A gene expression map for the euchromatic genome of Drosophila melanogaster.

    Science.gov (United States)

    Stolc, Viktor; Gauhar, Zareen; Mason, Christopher; Halasz, Gabor; van Batenburg, Marinus F; Rifkin, Scott A; Hua, Sujun; Herreman, Tine; Tongprasit, Waraporn; Barbano, Paolo Emilio; Bussemaker, Harmen J; White, Kevin P

    2004-10-22

    We used a maskless photolithography method to produce DNA oligonucleotide microarrays with unique probe sequences tiled throughout the genome of Drosophila melanogaster and across predicted splice junctions. RNA expression of protein coding and nonprotein coding sequences was determined for each major stage of the life cycle, including adult males and females. We detected transcriptional activity for 93% of annotated genes and RNA expression for 41% of the probes in intronic and intergenic sequences. Comparison to genome-wide RNA interference data and to gene annotations revealed distinguishable levels of expression for different classes of genes and higher levels of expression for genes with essential cellular functions. Differential splicing was observed in about 40% of predicted genes, and 5440 previously unknown splice forms were detected. Genes within conserved regions of synteny with D. pseudoobscura had highly correlated expression; these regions ranged in length from 10 to 900 kilobase pairs. The expressed intergenic and intronic sequences are more likely to be evolutionarily conserved than nonexpressed ones, and about 15% of them appear to be developmentally regulated. Our results provide a draft expression map for the entire nonrepetitive genome, which reveals a much more extensive and diverse set of expressed sequences than was previously predicted.

  14. Sequence Analysis of SSR-Flanking Regions Identifies Genome Affinities between Pasture Grass Fungal Endophyte Taxa

    Directory of Open Access Journals (Sweden)

    Eline van Zijll de Jong

    2011-01-01

    Full Text Available Fungal species of the Neotyphodium and Epichloë genera are endophytes of pasture grasses showing complex differences of life-cycle and genetic architecture. Simple sequence repeat (SSR markers have been developed from endophyte-derived expressed sequence tag (EST collections. Although SSR array size polymorphisms are appropriate for phenetic analysis to distinguish between taxa, the capacity to resolve phylogenetic relationships is limited by both homoplasy and heteroploidy effects. In contrast, nonrepetitive sequence regions that flank SSRs have been effectively implemented in this study to demonstrate a common evolutionary origin of grass fungal endophytes. Consistent patterns of relationships between specific taxa were apparent across multiple target loci, confirming previous studies of genome evolution based on variation of individual genes. Evidence was obtained for the definition of endophyte taxa not only through genomic affinities but also by relative gene content. Results were compatible with the current view that some asexual Neotyphodium species arose following interspecific hybridisation between sexual Epichloë ancestors. Phylogenetic analysis of SSR-flanking regions, in combination with the results of previous studies with other EST-derived SSR markers, further permitted characterisation of Neotyphodium isolates that could not be assigned to known taxa on the basis of morphological characteristics.

  15. Spider web glue: two proteins expressed from opposite strands of the same DNA sequence.

    Science.gov (United States)

    Choresh, Omer; Bayarmagnai, Battuya; Lewis, Randolph V

    2009-10-12

    The various silks that make up the web of the orb web spiders have been studied extensively. However, success in prey capture depends as much on the web glue as on the fibers. Spider silk glue, which is considered one of the strongest and most effective biological glues, is an aqueous solution secreted from the orb weaving spider's aggregate glands and coats the spiral prey capturing threads of their webs. Studies identified the major component of the glue as microscopic nodules made of a glycoprotein. This study describes two newly discovered proteins that form the glue-glycoprotein of the golden orb weaving spider Nephila clavipes . Our results demonstrate that both proteins contain unique 110 amino acid repetitive domains that are encoded by opposite strands of the same DNA sequence. Thus, the genome of the spider encodes two distinct yet functionally related genes by using both strands of an identical DNA sequence. Moreover, the closest match for the nonrepetitive region of one of the proteins is chitin binding proteins. The web glue appears to have evolved a substantial level of sophistication matching that of the spider silk fibers.

  16. Novel microsatellite markers and single nucleotide polymorphisms refine the tylosis with oesophageal cancer (TOC) minimal region on 17q25 to 42.5 kb: sequencing does not identify the causative gene.

    Science.gov (United States)

    Langan, Joanne E; Cole, Charlotte G; Huckle, Elisabeth J; Byrne, Shaun; McRonald, Fiona E; Rowbottom, Lynn; Ellis, Anthony; Shaw, Joan M; Leigh, Irene M; Kelsell, David P; Dunham, Ian; Field, John K; Risk, Janet M

    2004-05-01

    Tylosis (focal non-epidermolytic palmoplantar keratoderma) is associated with the early onset of squamous cell oesophageal cancer in three families. Linkage and haplotype analyses have previously mapped the tylosis with oesophageal cancer ( TOC) locus to a 500-kb region on chromosome 17q25 that has also been implicated in sporadically occurring squamous cell oesophageal cancer. In the current study, 17 additional putative microsatellite markers were identified within this 500-kb region by using sequence data and seven of these were shown to be polymorphic in the UK and US families. In addition, our complete sequence analysis of the non-repetitive parts of the TOC minimal region identified 53 novel and six known single nucleotide polymorphisms (SNPs) in one or both of these families. Further fine mapping of the TOC disease locus by haplotype analysis of the seven polymorphic markers and 21 of the 59 SNPs allowed the reduction of the minimal region to 42.5 kb. One known and two putative genes are located within this region but none of these genes shows tylosis-specific mutations within their protein-coding regions. Alternative mechanisms of disease gene action must therefore be considered.

  17. ESBL Production Among E. coli and Klebsiella spp. Causing Urinary Tract Infection: A Hospital Based Study.

    Science.gov (United States)

    Shakya, Pooja; Shrestha, Dhiraj; Maharjan, Elina; Sharma, Vijay K; Paudyal, Rabin

    2017-01-01

    Increase in extended-spectrum β-lactamases (ESBL) producing microbes in recent years has led to limitations of treatment options. This study aimed to assess the prevalence of ESBL producing E. coli and Klebsiella spp. at a tertiary hospital in Nepal. A total of 2209 non-repetitive mid-stream urine (MSU) samples were collected during the study period (March to September 2014). Identification of the isolates was done by Gram's staining followed by biochemical tests. Antibiotic susceptibility testing was done by modified Kirby-Bauer disc diffusion method and interpretation was done following Clinical and Laboratory Standard Institute (CLSI) guidelines, 2013. ESBL screening among E. coli and Klebsiella spp. isolates were done using ceftriaxone, cefotaxime, ceftazidime and cefpodoxime. The confirmation was done by phenotypic disc diffusion test (combined disc method) using ceftazidime (30µg) and ceftazidime plus clavulanic acid (30/10µg), and cefotaxime (30µg) and cefotaxime plus clavulanic acid (30/10µg) disc as per CLSI guidelines. A total of 451 samples showed significant bacteriuria with 365 (80.9%) E. coli, 17 (3.8%) Klebsiella pneumoniae and 3 (0.7%) Klebsiella oxytoca. Of 451 isolates, 236 (52.3%) were found MDR strains. By combined disk test, 33 (91.7%) E. coli and 3 (8.3%) Klebsiella spp. were found ESBL producers. Higher prevalence of ESBL producing E. coli and Klebsiella spp. was observed warranting prompt need of surveillance for effective management of such MDR strains.

  18. SNP high-throughput screening in grapevine using the SNPlex™ genotyping system

    Directory of Open Access Journals (Sweden)

    Velasco Riccardo

    2008-01-01

    Full Text Available Abstract Background Until recently, only a small number of low- and mid-throughput methods have been used for single nucleotide polymorphism (SNP discovery and genotyping in grapevine (Vitis vinifera L.. However, following completion of the sequence of the highly heterozygous genome of Pinot Noir, it has been possible to identify millions of electronic SNPs (eSNPs thus providing a valuable source for high-throughput genotyping methods. Results Herein we report the first application of the SNPlex™ genotyping system in grapevine aiming at the anchoring of an eukaryotic genome. This approach combines robust SNP detection with automated assay readout and data analysis. 813 candidate eSNPs were developed from non-repetitive contigs of the assembled genome of Pinot Noir and tested in 90 progeny of Syrah × Pinot Noir cross. 563 new SNP-based markers were obtained and mapped. The efficiency rate of 69% was enhanced to 80% when multiple displacement amplification (MDA methods were used for preparation of genomic DNA for the SNPlex assay. Conclusion Unlike other SNP genotyping methods used to investigate thousands of SNPs in a few genotypes, or a few SNPs in around a thousand genotypes, the SNPlex genotyping system represents a good compromise to investigate several hundred SNPs in a hundred or more samples simultaneously. Therefore, the use of the SNPlex assay, coupled with whole genome amplification (WGA, is a good solution for future applications in well-equipped laboratories.

  19. Analysis on multiple-component synchronization of ultra-fast time-interleaved analog-to-digital conversion systems and its novel parameterized hardware solution.

    Science.gov (United States)

    Huang, Wuhuang; Wang, Houjun; Tian, Shulin; Ye, Peng; Zeng, Hao; Qiu, Duyu

    2014-10-01

    Parallelism-based technique of time-interleaved analog-to-digital conversion (TIADC) has become an effective solution for the higher sampling rate acquisition system to acquire non-repetitive waveforms. With the increase of sampling frequency, the indeterminacy of combining sequence of sampled data among multiple components has become a highlighted barrier for the reset operation of high-speed acquisition systems, and this is especially obvious for the ultra-fast TIADC systems. In this paper, we clarify the root of the problem in multiple-component synchronization (MCS) caused by such reset operation. Also we propose a novel and reliable hardware solution to precisely condition each reset signal, including three key circuit design parameters, i.e., the best time interval, required edge uncertainty, and the minimum delay precision. Besides, the designing scheme and debugging procedures are presented in detail in a generalized platform of this system type. Finally, in order to demonstrate the feasibility, parametric materialization and testing verification are gradually accomplished in a 20 Giga Samples Per Second (GSPS) TIADC system composed of four 5 GSPS ADC components. The results show that the proposed method is feasible and effective for ensuring the combined determinacy of multiple groups of sampled data and solving the MCS problem. In comparison with other existing solutions, it adopts some simple logic components more easily and flexibly, and this is significant for the development of congeneric systems or instruments featuring the MCS.

  20. Unique molecular architecture of egg case silk protein in a spider, Nephila clavata.

    Science.gov (United States)

    Zhao, Aichun; Zhao, Tianfu; Sima, Yanghu; Zhang, Yuansong; Nakagaki, Koichi; Miao, Yungen; Shiomi, Kunihiro; Kajiura, Zenta; Nagata, Yoko; Nakagaki, Masao

    2005-11-01

    We describe a unique silk protein secreted from the cylindrical silk glands of the spider Nephila clavata. This silk is primarily composed of three proteins, whose transcripts of approximately 16.0, 14.5 and 13.0 kb are homologous to one another in two termini and repetitive units, as determined on Northern blotting. Its overall organization shows that it is similar to other characterized silk proteins, including in the mainly central repetitive region as well as the non-repetitive N-terminal (166 residues) and C-terminal (176 residues) parts. However, up to 90% of the protein consists of highly ordered repetitive structures that are not found in other silks. The repetitive region mainly consists of several types of complexes and remarkably conserved polypeptide repeats. The assembled repeat units (A1B1) contain a high proportion of Ala (30.41%), Ser (25.15%), and residues with hydrophobic side chains (22.22% for Gly, Leu, Ile, Val and Phe combined). The presence of Ser-rich and GVGAGASA motifs suggests the formation of a beta-sheet. The repetitive region is characterized by alternating arrays of hydrophobic and hydrophilic blocks. The results suggested that this egg case silk is an exceptional protein when compared with previously investigated spider silks.

  1. Identification and characterization of multiple Spidroin 1 genes encoding major ampullate silk proteins in Nephila clavipes.

    Science.gov (United States)

    Gaines, W A; Marcotte, W R

    2008-09-01

    Spider dragline silk is primarily composed of proteins called major ampullate spidroins (MaSps) that consist of a large repeat array flanked by nonrepetitive N- and C-terminal domains. Until recently, there has been little evidence for more than one gene encoding each of the two major spidroin silk proteins, MaSp1 and MaSp2. Here, we report the deduced N-terminal domain sequences for two distinct MaSp1 genes from Nephila clavipes (MaSp1A and MaSp1B) and for MaSp2. All three MaSp genes are co-expressed in the major ampullate gland. A search of the GenBank database also revealed two distinct MaSp1 C-terminal domain sequences. Sequencing confirmed that both MaSp1 genes are present in all seven Nephila clavipes spiders examined. The presence of nucleotide polymorphisms in these genes confirmed that MaSp1A and MaSp1B are distinct genetic loci and not merely alleles of the same gene. We experimentally determined the transcription start sites for all three MaSp genes and established preliminary pairing between the two MaSp1 N- and C-terminal domains. Phylogenetic analysis of these new sequences and other published MaSp N- and C-terminal domain sequences illustrated that duplications of MaSp genes may be widespread among spider species.

  2. Structural Model for the Spider Silk Protein Spidroin-1.

    Science.gov (United States)

    dos Santos-Pinto, José Roberto Aparecido; Arcuri, Helen Andrade; Priewalder, Helga; Salles, Heliana Clara; Palma, Mario Sergio; Lubec, Gert

    2015-09-04

    Most reports about the 3-D structure of spidroin-1 have been proposed for the protein in solid state or for individual domains of these proteins. A gel-based mass spectrometry strategy using collision-induced dissociation (CID) and electron-transfer dissociation (ETD) fragmentation methods was used to completely sequence spidroins-1A and -1B and to assign a series of post-translational modifications (PTMs) on to the spidroin sequences. A total of 15 and 16 phosphorylation sites were detected on spidroin-1A and -1B, respectively. In this work, we present the nearly complete amino acid sequence of spidroin-1A and -1B, including the nonrepetitive N- and C-terminal domains and a highly repetitive central core. We also described a fatty acid layer surrounding the protein fibers and PTMs in the sequences of spidroin-1A and -1B, including phosphorylation. Thus, molecular models for phosphorylated spidroins were proposed in the presence of a mixture fatty acids/water (1:1) and submitted to molecular dynamics simulation. The resulting models presented high content of coils, a higher percentage of α-helix, and an almost neglected content of 310-helix than the previous models. Knowledge of the complete structure of spidroins-1A and -1B would help to explain the mechanical features of silk fibers. The results of the current investigation provide a foundation for biophysical studies of the mechanoelastic properties of web-silk proteins.

  3. Investigation of Effectiveness of Order Review and Release Models in Make to Order Supply Chain

    Directory of Open Access Journals (Sweden)

    Kundu Kaustav

    2016-01-01

    Full Text Available Nowadays customisation becomes more common due to vast requirement from the customers for which industries are trying to use make-to-order (MTO strategy. Due to high variation in the process, workload control models are extensively used for jobshop companies which usually adapt MTO strategy. Some authors tried to implement workload control models, order review and release systems, in non-repetitive manufacturing companies, where there is a dominant flow in production. Those models are better in shop floor but their performances are never been investigated in high variation situations like MTO supply chain. This paper starts with the introduction of particular issues in MTO companies and a general overview of order review and release systems widely used in the industries. Two order review and release systems, the Limited and Balanced models, particularly suitable for flow shop system are applied to MTO supply chain, where the processing times are difficult to estimate due to high variation. Simulation results show that the Balanced model performs much better than the Limited model if the processing times can be estimated preciously.

  4. Lipid-specific β-sheet formation in a mussel byssus protein domain.

    Science.gov (United States)

    Heim, Markus; Elsner, Martina B; Scheibel, Thomas

    2013-09-09

    Intrinsically disordered proteins (IDP) or regions (IDR) can adopt multiple conformational states, depending on the interaction partners they encounter. This enables proteins or individual domains to fulfill multiple functions. Here, we analyzed the flank sequences of preCol-NG, one of three collagenous proteins of a mussel byssus thread governing its mechanical performance. preCol-NG comprises a collagen domain and nonrepetitive termini enclosing specific flank regions characterized by tandem repeats known from silk proteins, protein elastomers, and plant cell wall-associated proteins. We recombinantly produced a protein mimicking the M. galloprovincialis preCol-NG C-terminal flank region. The protein was intrinsically unfolded in solution, even at elevated temperatures. However, upon contact with small unilamellar vesicles (SUVs) reversible β-structure formation occurred, reminiscent of partitioning-folding coupling. This behavior of preCol-NG flank domains likely impacts byssogenesis and sheds new light on a distinct mechanism of how fibrous protein materials might be achieved by lipid-induced self-assembly in nature.

  5. Paternity test in "Mangalarga-Marchador" equines by DNA-fingerprinting

    Directory of Open Access Journals (Sweden)

    ANUNCIAÇÃO CARLOS EDUARDO

    2000-01-01

    Full Text Available GC-rich molecular minisatellite probes isolated from the human genome have presented a poor ability for individualization in horses. In this study new DNA sequences were isolated which could be used in paternity tests in horses. Genomic DNA from "Mangalarga-Marchador" horses was treated with restriction enzymes that preferentially digest non-repetitive sequences, so preserving the structure where mini and microsatellites are located. Four clones (S01, S05, S07 and S09 selected from a genomic library screened with a (TGn oligonucleotide showed similar hybridization profiles generating bands of DNA-fingerprinting type. Using these probes the individualization power obtained was 10-8, which is 10(5fold higher than that obtained with M13, another GC-rich type probe. All clones were efficient in parentage detection in crossbreedings and presented a 27 bp consensus sequence, GTTTCATTTATTATTCTTTGGAAGAAA, which was repeated 12, 18, 11 and 21 times in clones S01, S05, S07 and S09, respectively.

  6. Autonomous biomorphic robots as platforms for sensors

    Energy Technology Data Exchange (ETDEWEB)

    Tilden, M.; Hasslacher, B.; Mainieri, R.; Moses, J.

    1996-10-01

    The idea of building autonomous robots that can carry out complex and nonrepetitive tasks is an old one, so far unrealized in any meaningful hardware. Tilden has shown recently that there are simple, processor-free solutions to building autonomous mobile machines that continuously adapt to unknown and hostile environments, are designed primarily to survive, and are extremely resistant to damage. These devices use smart mechanics and simple (low component count) electronic neuron control structures having the functionality of biological organisms from simple invertebrates to sophisticated members of the insect and crab family. These devices are paradigms for the development of autonomous machines that can carry out directed goals. The machine then becomes a robust survivalist platform that can carry sensors or instruments. These autonomous roving machines, now in an early stage of development (several proof-of-concept prototype walkers have been built), can be developed so that they are inexpensive, robust, and versatile carriers for a variety of instrument packages. Applications are immediate and many, in areas as diverse as prosthetics, medicine, space, construction, nanoscience, defense, remote sensing, environmental cleanup, and biotechnology.

  7. Genome-scale functional characterization of Drosophila developmental enhancers in vivo.

    Science.gov (United States)

    Kvon, Evgeny Z; Kazmar, Tomas; Stampfel, Gerald; Yáñez-Cuna, J Omar; Pagani, Michaela; Schernhuber, Katharina; Dickson, Barry J; Stark, Alexander

    2014-08-01

    Transcriptional enhancers are crucial regulators of gene expression and animal development and the characterization of their genomic organization, spatiotemporal activities and sequence properties is a key goal in modern biology. Here we characterize the in vivo activity of 7,705 Drosophila melanogaster enhancer candidates covering 13.5% of the non-coding non-repetitive genome throughout embryogenesis. 3,557 (46%) candidates are active, suggesting a high density with 50,000 to 100,000 developmental enhancers genome-wide. The vast majority of enhancers display specific spatial patterns that are highly dynamic during development. Most appear to regulate their neighbouring genes, suggesting that the cis-regulatory genome is organized locally into domains, which are supported by chromosomal domains, insulator binding and genome evolution. However, 12 to 21 per cent of enhancers appear to skip non-expressed neighbours and regulate a more distal gene. Finally, we computationally identify cis-regulatory motifs that are predictive and required for enhancer activity, as we validate experimentally. This work provides global insights into the organization of an animal regulatory genome and the make-up of enhancer sequences and confirms and generalizes principles from previous studies. All enhancer patterns are annotated manually with a controlled vocabulary and all results are available through a web interface (http://enhancers.starklab.org), including the raw images of all microscopy slides for manual inspection at arbitrary zoom levels.

  8. The structure of the carbohydrate backbone of the lipopolysaccharide of Pectinatus frisingensis strain VTT E-79104.

    Science.gov (United States)

    Vinogradov, Evgeny; Li, Jianjun; Sadovskaya, Irina; Jabbouri, Said; Helander, Ilkka M

    2004-06-22

    The structure of the carbohydrate backbone of the lipopolysaccharide from Pectinatus frisingensis strain VTT E-79104 was analyzed using chemical degradations, NMR spectroscopy, mass spectrometry, and chemical methods. The LPS contains two major structural variants, differing in the presence or absence of an octasaccharide fragment. The largest structure of the carbohydrate backbone of the LPS, that could be deduced from experimental results, consists of 20 monosaccharides arranged in a nonrepetitive sequence: [carbohydrate structure: see text] where R is H or 4-O-Me-alpha-L-Fuc-(1-2)-4-O-Me-beta-Hep-(1-3)-alpha-GlcNAc-(1-2)-beta-Man-(1-3)-beta-ManNAc-(1-4)-alpha-Gal-(1-4)-beta-Hep-(1-3)-beta-GalNAc-(1- where Hep is a residue of D-glycero-D-galacto-heptose; all monosaccharides have the D-configuration except for 4-O-Me-L-Fuc and L-Ara4N. This structure is architecturally similar to the oligosaccharide system reported previously in P. frisingensis VTT E-82164 LPS, but differs from the latter in composition and also in the size of the outer region.

  9. Observation of large photoacoustic signal phase changes during a diffusion process.

    Science.gov (United States)

    Bajic, Stanley J; Jones, Roger W; McClelland, John F

    2005-11-01

    The phase of the photoacoustic signal is known to be a sensitive and accurate means to investigate, both qualitatively and quantitatively, static multilayer heterogeneous systems. According to theory, the maximum phase delay for a very weakly absorbing homogeneous sample should be within 45 degrees of a very strongly absorbing sample, while for heterogeneous samples the phase delay can be greater than 45 degrees. Here we report the observation of photoacoustic phase delays greater than 350 degrees by extending the use of step-scan phase modulation photoacoustic spectroscopy to study a non-repetitive dynamic system in situ, in real time. These large phase delays correspond to sampling several thermal diffusion lengths into the sample. The model system used in this study consisted of a hydrocarbon grease diffusing through a porous Teflon film. The progress of the diffusion was tracked by monitoring both the photoacoustic signal magnitude and the phase of the hydrocarbon grease after isolation from the Teflon film signal contributions at two different phase modulation frequencies.

  10. Topographic mapping of oral structures - problems and applications in prosthodontics

    Science.gov (United States)

    Young, John M.; Altschuler, Bruce R.

    1981-10-01

    The diagnosis and treatment of malocclusion, and the proper design of restorations and prostheses, requires the determination of surface topography of the teeth and related oral structures. Surface contour measurements involve not only affected teeth, but adjacent and opposing surface contours composing a complexly interacting occlusal system. No a priori knowledge is predictable as dental structures are largely asymmetrical, non-repetitive, and non-uniform curvatures in 3-D space. Present diagnosis, treatment planning, and fabrication relies entirely on the generation of physical replicas during each stage of treatment. Fabrication is limited to materials that lend themselves to casting or coating, and to hand fitting and finishing. Inspection is primarily by vision and patient perceptual feedback. Production methods are time-consuming. Prostheses are entirely custom designed by manual methods, require costly skilled technical labor, and do not lend themselves to centralization. The potential improvement in diagnostic techniques, improved patient care, increased productivity, and cost-savings in material and man-hours that could result, if rapid and accurate remote measurement and numerical (automated) fabrication methods were devised, would be significant. The unique problems of mapping oral structures, and specific limitations in materials and methods, are reviewed.

  11. Diversity, evolution, and functionality of clustered regularly interspaced short palindromic repeat (CRISPR) regions in the fire blight pathogen Erwinia amylovora.

    Science.gov (United States)

    Rezzonico, Fabio; Smits, Theo H M; Duffy, Brion

    2011-06-01

    The clustered regularly interspaced short palindromic repeat (CRISPR)/Cas system confers acquired heritable immunity against mobile nucleic acid elements in prokaryotes, limiting phage infection and horizontal gene transfer of plasmids. In CRISPR arrays, characteristic repeats are interspersed with similarly sized nonrepetitive spacers derived from transmissible genetic elements and acquired when the cell is challenged with foreign DNA. New spacers are added sequentially and the number and type of CRISPR units can differ among strains, providing a record of phage/plasmid exposure within a species and giving a valuable typing tool. The aim of this work was to investigate CRISPR diversity in the highly homogeneous species Erwinia amylovora, the causal agent of fire blight. A total of 18 CRISPR genotypes were defined within a collection of 37 cosmopolitan strains. Strains from Spiraeoideae plants clustered in three major groups: groups II and III were composed exclusively of bacteria originating from the United States, whereas group I generally contained strains of more recent dissemination obtained in Europe, New Zealand, and the Middle East. Strains from Rosoideae and Indian hawthorn (Rhaphiolepis indica) clustered separately and displayed a higher intrinsic diversity than that of isolates from Spiraeoideae plants. Reciprocal exclusion was generally observed between plasmid content and cognate spacer sequences, supporting the role of the CRISPR/Cas system in protecting against foreign DNA elements. However, in several group III strains, retention of plasmid pEU30 is inconsistent with a functional CRISPR/Cas system.

  12. Alternate phase variation in expression of two major surface membrane proteins (MBA and UU376) of Ureaplasma parvum serovar 3.

    Science.gov (United States)

    Zimmerman, Carl-Ulrich R; Stiedl, Thomas; Rosengarten, Renate; Spergser, Joachim

    2009-03-01

    Ureaplasma urealyticum and Ureaplasma parvum are commensals and pathogens of the human urogenital tract and of newborn infants. There are four distinct U. parvum serovars and 10 distinct U. urealyticum serovars. Both species possess a distinct immunodominant variable surface protein, the multiple banded antigen (MBA), which shows size variability among isolates as a result of changes in the number of C-terminal repeating units. Adjacent to the MBA gene (UU375) lies UU376, which was annotated as 'Ureaplasma-specific conserved hypothetical gene'. In four different strains of U. parvum serovar 3, we demonstrated expression of UU376 by Western blot analysis and phase variation between UU376, here designated Upvmp376 (Ureaplasma phase-variable membrane protein 376), and MBA after application of selective pressure with hyperimmune antisera directed against either protein. By Southern blot analysis, we found that the switch between MBA and Upvmp376 expression is associated with a DNA inversion event in which the nonrepetitive region of the MBA gene and its putative promoter region are opposed to either the repetitive region of MBA or UU376. We propose that in U. parvum serovar 3, and presumably in all U. parvum and U. urealyticum, an inversion event at specific sites effects an alternate ON/OFF switching of the genes UU375 and UU376.

  13. Entropic Measure of Epistemic Uncertainties in Multibody System Models by Axiomatic Design

    Directory of Open Access Journals (Sweden)

    Francesco Villecco

    2017-06-01

    Full Text Available In this paper, the use of the MaxInf Principle in real optimization problems is investigated for engineering applications, where the current design solution is actually an engineering approximation. In industrial manufacturing, multibody system simulations can be used to develop new machines and mechanisms by using virtual prototyping, where an axiomatic design can be employed to analyze the independence of elements and the complexity of connections forming a general mechanical system. In the classic theories of Fisher and Wiener-Shannon, the idea of information is a measure of only probabilistic and repetitive events. However, this idea is broader than the probability alone field. Thus, the Wiener-Shannon’s axioms can be extended to non-probabilistic events and it is possible to introduce a theory of information for non-repetitive events as a measure of the reliability of data for complex mechanical systems. To this end, one can devise engineering solutions consistent with the values of the design constraints analyzing the complexity of the relation matrix and using the idea of information in the metric space. The final solution gives the entropic measure of epistemic uncertainties which can be used in multibody system models, analyzed with an axiomatic design.

  14. Impact and sensitivity of parameters in debris flow models: A Monte Carlo simulation on fluid rheology, geometry and position of release areas

    Science.gov (United States)

    Robl, Jörg; Hergarten, Stefan

    2015-04-01

    Debris flows are globally abundant threats for settlements and infrastructure in mountainous regions. Crucial influencing factors for hazard zone planning and mitigation strategies are based on numerical models that describe granular flow on general topography by solving a depth-averaged form of the Navier Stokes equations in combination with an appropriate flow resistance law. In case of debris flows, the Voellmy rheology is a widely used constitutive law describing the flow resistance. It combines a velocity independent Coulomb friction term with a term proportional to the square of the velocity as it is commonly used for turbulent flow. Parameters of the Vollemy fluid are determined by back analysis from observed events so that modelled events mimic their historical counterparts. Determined parameters characterizing individual debris flows show a large variability (related to fluid composition and surface roughness). However, there may be several sets of parameters that lead to a similar depositional pattern but cause large differences in flow velocity and momentum along the flow path. Fluid volumes of hazardous debris flows are estimated by analyzing historic events, precipitation time series, hydrographs or empirical relationships that correlate fluid volumes and drainage areas of torrential catchments. Beside uncertainties in the determination of the fluid volume the position and geometry of the initial masses of forthcoming debris flows are in general not well constrained but heavily influence the flow dynamics and the depositional pattern even in the run-out zones. In this study we present a new, freely available numerical description of rapid mass movements based on the GERRIS framework and early results of a Monte Carlo simulation exploring effects of the aforementioned parameters on run-out distance, inundated area and momentum. The novel numerical model describes rapid mass movements on complex topography using the shallow water equations in Cartesian

  15. Rockfall hazard assessment integrating probabilistic physically based rockfall source detection (Norddal municipality, Norway).

    Science.gov (United States)

    Yugsi Molina, F. X.; Oppikofer, T.; Fischer, L.; Hermanns, R. L.; Taurisano, A.

    2012-04-01

    Traditional techniques to assess rockfall hazard are partially based on probabilistic analysis. Stochastic methods has been used for run-out analysis of rock blocks to estimate the trajectories that a detached block will follow during its fall until it stops due to kinetic energy loss. However, the selection of rockfall source areas is usually defined either by multivariate analysis or by field observations. For either case, a physically based approach is not used for the source area detection. We present an example of rockfall hazard assessment that integrates a probabilistic rockfall run-out analysis with a stochastic assessment of the rockfall source areas using kinematic stability analysis in a GIS environment. The method has been tested for a steep more than 200 m high rock wall, located in the municipality of Norddal (Møre og Romsdal county, Norway), where a large number of people are either exposed to snow avalanches, rockfalls, or debris flows. The area was selected following the recently published hazard mapping plan of Norway. The cliff is formed by medium to coarse-grained quartz-dioritic to granitic gneisses of Proterozoic age. Scree deposits product of recent rockfall activity are found at the bottom of the rock wall. Large blocks can be found several tens of meters away from the cliff in Sylte, the main locality in the Norddal municipality. Structural characterization of the rock wall was done using terrestrial laser scanning (TLS) point clouds in the software Coltop3D (www.terranum.ch), and results were validated with field data. Orientation data sets from the structural characterization were analyzed separately to assess best-fit probability density functions (PDF) for both dip angle and dip direction angle of each discontinuity set. A GIS-based stochastic kinematic analysis was then carried out using the discontinuity set orientations and the friction angle as random variables. An airborne laser scanning digital elevation model (ALS-DEM) with 1 m

  16. The Large-Scale Debris Avalanche From The Tancitaro Volcano (Mexico): Characterization And Modeling

    Science.gov (United States)

    Morelli, S.; Gigli, G.; Falorni, G.; Garduno Monroy, V. H.; Arreygue, E.

    2008-12-01

    until they disappear entirely in the most distal reaches. The granulometric analysis and the comparison between the debris avalanche of the Tancitaro and other collapses with similar morphometric features (vertical relief during runout, travel distance, volume and area of the deposit) indicate that the collapse was most likely not primed by any type of eruption, but rather triggered by a strong seismic shock that could have induced the failure of a portion of the edifice, already deeply altered by intense hydrothermal fluid circulation. It is also possible to hypothesize that mechanical fluidization may have been the mechanism controlling the long runout of the avalanche, as has been determined for other well-known events. The behavior of the Tancitaro debris avalanche was numerically modeled using the DAN-W code. By opportunely modifying the rheological parameters of the different models selectable within DAN, it was determined that the two-parameter 'Voellmy model' provides the best approximation of the avalanche movement. The Voellmy model produces the most realistic results in terms of runout distance, velocity and spatial distribution of the failed mass. Since the Tancitaro event was not witnessed directly, it is possible to infer approximate velocities only from comparisons with similar and documented events, namely the Mt. St. Helens debris avalanche occurred on May 18, 1980.

  17. 圆柱滚子轴承旋转精度数值计算及试验研究%Numerical Calculation and Experimental Research of Rotational Accuracy on Cylindrical Roller Bearing

    Institute of Scientific and Technical Information of China (English)

    余永健; 李济顺; 陈国定; 薛玉君; 刘永刚; 史文祥

    2016-01-01

    Aiming to rotational accuracy of cylindrical roller bearing, the radial runout of outer ring of assembled bearing is studied by numerical computation, and form error of outer ring raceway is experimentally investigated. According to the motion and geometric relationships among bearing components, a mathematical model for cylindrical roller bearing is developed to investigate the influence of roundness error (i.e., amplitude, order) of outer ring raceway, the number of roller and radial clearance on rotational accuracy of cylindrical roller bearing. The model is validated to be reasonable by theory calculation results. The results indicate that the roundness error of outer ring raceway has a significant impact on rotational accuracy of cylindrical roller bearing. When the roundness error order and number of roller satisfy certain conditions, the rotational accuracy of cylindrical roller bearing significantly decreases. When the surface waveform of outer ring raceway changes sharply, the influence of the number of roller on rotational accuracy of cylindrical roller bearing is obvious. The roundness error of outer ring raceway is experimentally investigated. The results show that the roundness error of outer ring raceway is subject to normal distribution. Amplitude and order of roundness error change exponentially. The function relation between the radial runout of outer ring and harmonic distribution parameters of outer ring raceway is obtained. This function relation is used to predict the radial runout of outer ring.%针对圆柱滚子轴承旋转精度,提出了轴承外圈径向跳动数值计算方法,并对外圈滚道形状误差进行了试验研究。根据轴承元件运动及几何关系,建立了轴承外圈径向跳动数值计算模型,分析了外圈滚道圆度误差幅值、圆度误差阶次、滚子个数以及径向游隙对轴承旋转精度的影响规律,并验证了模型的正确性。分析结果表明,外圈滚道圆度误差

  18. Advanced Susceptibility Mapping for Natural Hazards at a Local Scale - The Case of the Swiss Alpine Valley of Bagnes.

    Science.gov (United States)

    Michoud, Clément; Mazotti, Benoît.; Choffet, Marc; Dubois, Jérôme; Breguet, Alain; Métraux, Valentin; Jaboyedoff, Michel

    2010-05-01

    Alpine municipalities are exposed to numerous natural hazards, such as snow avalanches, rockfalls, landslides and debris flows. The Bagnes and Vollèges municipalities in Valais (Switzerland) lie between 600 m and 4200 m m.s.l. with an area of 300 km2. The anthropization is rapid because of the fast growing ski resort of Verbier. In such situation the municipalities needs to have global overview of the natural hazards for landplaning purpose and decision making. The susceptibility mapping at regional scale allows the detection of the areas that are exposed to natural hazards, without considering the intensity and the frequency of the phenomena. The aim of this study is to provide susceptibility maps at 1:25'000 for the following natural hazards: landslides, shallow landslides, rockfalls, debris flows, snow avalanches, flooding and river overflowing. The present method was first developed for the Canton of Vaud (2'800 km2). Because it is applied to a smaller area, more numerical models and field investigations were performed. In addition historical event were included in the study. 1. The landslide mapping identifies deep-seated slope gravitational deformations, landslides and shallow landslides. It is based on the observations of geomorphological criteria on High Resolution DEM, orthophotos and field work. Finally, the activity of each landslide is described by the knowledge of local guides. 2. The shallow landslide susceptibility mapping is realized thanks to the software SInMap, calculating Security Factor (FS) and Stability Index (SI) according to the land use, the topography and the climatic conditions. The model is calibrated on the basis of the 67 shallow landslides already identified for the first map. 3. The rockfall susceptibility mapping is a two steps process. First, the potential source areas of blocks are detected using a statistical analysis of the slope angle distribution, including external knowledge on the geology and land cover. Then the run-out

  19. 2014年我院病原菌分布及耐药性分析%Analysis of pathogenic bacteria distribution and drug resistance in 2014 in our hospital

    Institute of Scientific and Technical Information of China (English)

    荣爱红

    2016-01-01

    Objective To explore the distribution and drug resistance of pathogenic bacteria clinically isolated from our hospital for providing scientific data for clinical prevention and treatment of anti-infection.Methods Strain identifi-cation and susceptibility tests were performed on 1578 non-repetitive strains isolated from clinical routine with a fully automatic microbial identification and drug susceptibility system called VITEK 2 COMPACT.Results There were 1578 non-repetitive strains,including 468 strains of gram-positive bacteria and 1110 strains of gram-negative bacteria. Gram-positive bacteria include staphylococcus aureus,enterococcus,coagulase negative staphylococcus,streptococcus pneumoniae.Gram-negative bacteria include klebsiella pneumonia,escherichia coli,acinetobacter baumannii,pseudo-monas aeruginosa,enterobacter cloacae.The detection rate of methicillin-resistant staphylococcus aureus is 43.0%.The resistance rates of escherichia coli and klebsiella pneumonia to the third-generation cephalosporins are 57.9% and 38.3% respectively.The resistance rate of acinetobacter baumannii on carbopenems is 62.0%.Conclusion There are various kinds of pathogenic bacteria clinically isolated from our hospital,and the drug resistance of pathogenic bacteria differ obviously.It is suggested to raise the clinical detection rate,to strengthen the monitoring of bacterial drug resist-ance.We should select antibacterial agents reasonably according to the drug resistant spectrum of pathogenic bacteria,in order to reduce the occurrence of bacterial resistance.%目的:探讨2014年我院临床分离病原菌的分布及耐药性,为临床抗感染防治提供科学数据。方法对临床常规培养分离的1578株非重复菌株用 VITEK 2 COMPACT 全自动微生物鉴定及药敏系统进行菌株鉴定和药敏试验。结果非重复菌株共1578株,包括革兰阳性菌468株,革兰阴性菌1110株。革兰阳性菌主要包括金黄色葡萄球菌、肠球菌、

  20. 2009~2012年重庆医科大学附属第一医院粪肠球菌和屎肠球菌耐药性监测%The resistance surveillance of Enterococcus faecalis and Enterococcus faecium from the First Affiliated Hospital of Chongqing Medical University between 2009 and 2012

    Institute of Scientific and Technical Information of China (English)

    黎七绮; 牛司强

    2014-01-01

    Objective To investigate the antimicrobial resistance of Enterococcus f aecalis and Enterococcus f aecium isolated from the First Affiliated Hospital of Chongqing Medical University between 2009 and 2012 .Methods Antimicrobial susceptibility testing was carried out according to the unified protocol .The dates were analyzed by WHONET 5 .6 software according to clinical and laboratory standards institute(CLSI) of 2012 .Results A total of 783 non-repetitive Enterococcus f aecalis and 664 non-repeti-tive Enterococcus f aecium isolates were collected .The strains were still highly susceptible to linezolid and vancomycin .The resist-ance rates were all less than 2 .0% .The resistance rates of vancomycin to Enterococcus f aecalis and Enterococcus f aecium were 0 .1% and 1 .4% ,respectively .The percentage of Enterococcus f aecalis resistant to ampicillin ,penicilin and nitrofurantoin were 5 .7% ,2 .6% and 2 .2% ,respectively .About 32 .9% of Enterococcus f aecalis isolates were resistant to gentamicin .The resistance rates of ampicillin and penicillin to Enterococcus f aecium were more than 90 .0% .Conclusion Enterococcus f aecalis is main En-terococcus in the First Affiliated Hospital of Chongqing Medical University .There is an obvious difference between the antibiotic re-sistance of the Enterococcus f aecalis and Enterococcus f aecium .So ,monitoring drug resistance of the Enterococcus shows great sig-nificance to the clinical treatment .%目的:了解2009~2012年重庆医科大学附属第一医院临床分离的粪肠球菌和屎肠球菌对各类抗菌药物的耐药性。方法临床分离病原菌按统一方案进行细菌药物敏感试验,根据2012年版临床实验室标准化协会(CLSI)指导原则判读细菌的药物敏感试验结果,采用WHONET5.6软件对数据进行分析。结果共分离到非重复粪肠球菌783株,屎肠球菌664株,二者对利奈唑胺和万古霉素非常敏感(耐药率均低于2.0%),粪肠球菌

  1. 船用齿轮箱刚度分析与实验%Stiffness analysis and experiments of marine gearbox

    Institute of Scientific and Technical Information of China (English)

    刘明勇; 朱才朝; 杜雪松; 徐向阳; 刘伟辉; 宁杰; 曹建新

    2012-01-01

    基于船用齿轮箱相关技术条件,考虑轴、轴承、箱体等变形及传动过程中的相互影响,提出以联轴器跳动值作为船用齿轮箱刚度评价的新方法。采用有限元法建立船用齿轮箱的刚度分析耦合模型,得到箱体与轴变形、轴承与轴承座刚度等参数,计算出齿轮箱联轴器跳动值;结合理论分析设计刚度测试实验,根据实验结果与理论分析相对比,误差在11%以内,且满足技术要求,说明以联轴器跳动值作为船用齿轮箱刚度评价的新方法是有效的。%Based on correlate technique conditions of marine gearbox,it is proposed to take run-out value of input and output couplings as the stiffness evaluation of marine gearbox. This new method is put forth on rated load by considering the deformation interrelationship in transmission of some main parts, such as shaft, bearing,gear and box. Finite element analysis of strength and deformation of marine gearbox under forward and backward conditions are conducted. Parameters, such as box and axis deformation, bearing and shaft block stiffness, etc. are obtained and run-out value of input and output couplings is calculated. Experiments are carried out at gear drive test bench to verify the reliable of stiffness evaluation method. Compared with the experimental results, the error is in 11%~,which shows the proposed stiffness method is valid.

  2. Slope stability analysis for Valles Marineris, Mars: a numerical analysis of controlling conditions and failure types

    Science.gov (United States)

    Crosta, G.; Castellanza, R.; De Blasio, F.; Utili, S.

    2012-04-01

    Valles Marineris (VM hereafter) in the equatorial area of Mars exhibits several gravitative failures often involving the whole 6-8 km thickness of the valley walls. The failures have resulted in a series of long-runout landslides up to several hundred cubic kilometres in volume (Quantin et al., 2004), and the formation of sub-circular alcoves perched on the top. Several questions arise as to forces at play in the stability of the walls of VM, the geometrical shape of the alcoves and the shape and long-runout of the landslides (see for example Lucas et al., 2011). In this work, we concentrate on the stability analysis of the walls of VM with two precise questions in mind starting from past studies (Bigot-Cormier and Montgomery, 2006; Neuffer and Schultz, 2006, Schultz, 2002). The first concerns the properties of the materials that give origin to instability. We performed several finite element and discrete element calculations tailored to slope stability analysis based on the genuine shape of the walls of VM taken from the MOLA topographic data. We considered stratified and differently altered/degraded materials to define the range of physical mechanical properties required for failure to occur and to explain the discrete distribution of failures along the VM valley flanks. A second question addressed in this work is the geometrical shape of the sub-circular alcoves. Normally, these shapes are commonplace for slopes made of uniform and isotropic properties, and are also observed in subaqueous environment. We performed calculations taking into consideration the progressive failure in the slope showing the final results in terms of surface failure geometry. Bigot-Cormier, F., Montgomery, D.R. (2007) Valles Marineris landslides: Evidence for a strength limit to Martian relief? Earth and Planetary Science Letters, 260, 1-2, 15, 179-186 Lucas, A., Mangeney, A., Mège, D., and Bouchut, F., 2011. Influence of the scar geometry on landslide dynamics and deposits

  3. The process of earthflow propagation: insights from an application of the SPH technique to a case history

    Science.gov (United States)

    Lollino, Piernicola; Giordan, Daniele; Allasia, Paolo; Pastor, Manuel

    2016-04-01

    An intense reactivation of a large earthflow (about 6 million m3 of soil debris) took place in Montaguto (Southern Apennines, Italy) between 2005 and 2006 as a consequence of the retrogression of a sliding process in the source area at the top of the slope. The earthflow run-out was approximately 2-2.5 km long, with the landslide mass thickness approximately ranging between 5 m and 30 m. Relevant damages were produced at the toe of the slope, since important infrastructures hereby located were covered by large volumes of landslide detritum. In the transition area, that is just downslope the source area, the landslide soil mass was channelized and transformed into a viscous soil flowing down through a natural depression channel, with an average displacement rate estimated to range between 3 and 7 m/day. In this work an application of the Smoothed Particle Hydrodynamics method has been carried out in order to simulate both the main features of the earthflow propagation, that is the direction and the thickness of the flowing mass, as well as to investigate some factors of the soil mechanical behavior that might have controlled the earthflow mobility. In particular, two different assumptions concerning the soil rheology, i.e. Bingham visco-plasticity and frictional-consolidating soil, the first complying more with the assumption of a flow-like behavior and the latter with a soil-like behavior of the landslide mass, have been made for comparison purposes. Based on the experiences gained from previous authors concerning the in-situ features of similar earthflow soil masses, these landslides are thought to behave more as a viscous fluid during the very first stages of propagation due to phase transition processes and, later on, to recover a soil-like behavior, therefore characterized by sliding mechanism, due to soil consolidation processes. Field evidences of consolidation processes have indeed been observed in situ in recent years based on pore water pressure monitoring

  4. A multi path, weather independent avalanche monitoring tool using distributed acoustic fiber optic sensing

    Science.gov (United States)

    Prokop, Alexander; Wirbel, Anna

    2013-04-01

    Information on avalanche activity is a paramount parameter in avalanche forecasting. When avalanches are released spontaneously, the risk of avalanches is very high. Triggering avalanches by artificial means, such as explosives launched from helicopter or avalanche towers, can also give information on the stability of the snow pack. Hence, monitoring of avalanches released naturally or artificially, is an important quantity in avalanche forecasting. This information is also needed when deciding whether to close or not endangered ski runs, roads or railway lines. So far monitoring systems lack certain benefits. Either they monitor only large avalanches, can only be used for single avalanche tracks or are weather/sight dependant. Therefore a new tool for avalanche- monitoring, a distributed fiber optic system, is for the first time installed and adapted for the purpose of monitoring snow avalanche activity. The method is based on an optical time domain reflectometer (OTDR) system, which dates back to the 1970`s and detects seismic vibrations and acoustic signals on a fiber optic cable that can have a length of up to 30 km. An appropriate test slope for this configuration has been found in the ski area of "Lech am Arlberg". In this work a detailed description of the theoretical background, the system implementation, the field installation, realization of tests and an investigation of the recorded data is presented. We conducted 100 tests and triggered 41 avalanches so far with a runout distances ranging from a few meters to approximately 250 meters, all of which were detected by the system, as well as the 59 not successful attempts of artificial triggering. Moreover we measured properly if critical infrastructure (in our case a ski run) was reached by the avalanches or not. The spatial distributed sensing approach allowed us to relate the amplitude and spectral content of the signals to avalanche size, avalanche speed and snow properties of the avalanches. In

  5. Investigating Dynamics of Eccentricity in Turbomachines

    Science.gov (United States)

    Baun, Daniel

    2010-01-01

    A methodology (and hardware and software to implement the methodology) has been developed as a means of investigating coupling between certain rotordynamic and hydrodynamic phenomena in turbomachines. Originally, the methodology was intended for application in an investigation of coupled rotordynamic and hydrodynamic effects postulated to have caused high synchronous vibration in the space shuttle s high-pressure oxygen turbopump (HPOTP). The methodology can also be applied in investigating (for the purpose of developing means of suppressing) undesired hydrodynamic rotor/stator interactions in turbomachines in general. The methodology and the types of phenomena that can be investigated by use of the methodology are best summarized by citing the original application as an example. In that application, in consideration of the high synchronous vibration in the space-shuttle main engine (SSME) HPOTP, it was determined to be necessary to perform tests to investigate the influence of inducer eccentricity and/or synchronous whirl motion on inducer hydrodynamic forces under prescribed flow and cavitation conditions. It was believed that manufacturing tolerances of the turbopump resulted in some induced runout of the pump rotor. Such runout, if oriented with an inducer blade, would cause that blade to run with tip clearance smaller than the tip clearances of the other inducer blades. It was hypothesized that the resulting hydraulic asymmetry, coupled with alternating blade cavitation, could give rise to the observed high synchronous vibration. In tests performed to investigate this hypothesis, prescribed rotor whirl motions have been imposed on a 1/3-scale water-rig version of the SSME LPOTP inducer (which is also a 4-biased inducer having similar cavitation dynamics as the HPOTP) in a magnetic-bearing test facility. The particular magnetic-bearing test facility, through active vibration control, affords a capability to impose, on the rotor, whirl orbits having shapes and

  6. A 3-D remote sensing system based on assessment of debris flow and impact area simulation%基于三维遥感系统的泥石流土石量计算及影响范围模拟

    Institute of Scientific and Technical Information of China (English)

    谢谟文; 刘翔宇; 王增福; 胡嫚

    2011-01-01

    结合三维遥感影像解译提出一种定量的泥石流土石量计算方法.在泥石流汇水区内对地形进行0次谷与1次谷划分,按可搬运的物质总量和一次降雨所能搬运的物质总量两种方式进行分析,使计算结果更加精细化;以数字高程模型(DEM)与降雨所搬运的土石总量作为影响范围模拟的基础,利用GIS空间分析功能分析泥石流汇水区的横截面面积及区域平面面积等地形参数,判别土石产出量与地形参数关系,实现泥石流影响范围的模拟.分析结果可为潜在泥石流危险区域评价预测提供参考.%A new quantitative calculation method of the earth-rock output of debris flow is presented in this paper.In the area of geological disaster development, the earth-rock output assessment is involved in both the surface loose accumulation and the output of the possible geological hazards, such as collapse and landslide.In the collection area of debris flow, the terrain is divided into 0-time valley and 1-time valley.Two methods are used to analyze the results of the calculation in order to make it more precise.One method is based on the existing earth-rock amount, the other is on the possible output which can be carried by rainfall runout.The simulation of influence area is based on DEM and the earth-rock output carried by rainfall runout.The GIS function of spatial analysis is used to obtain terrain parameters such as area of the cross section of the collection region of debris flow and area of the regional plane.The relationship between the amount of earth-rock discharge and terrain parameters is distinguished to realize the stimulation of the influence area of debris flow.The result of the analysis can provide a reference for the assessment of potential dangerous region of debris flow.

  7. Emerging insights into the dynamics of submarine debris flows

    Science.gov (United States)

    Elverhøi, A.; Issler, D.; de Blasio, F. V.; Ilstad, T.; Harbitz, C. B.; Gauer, P.

    2005-08-01

    Recent experimental and theoretical work on the dynamics of submarine debris flows is summarized. Hydroplaning was first discovered in laboratory flows and later shown to likely occur in natural debris flows as well. It is a prime mechanism for explaining the extremely long runout distances observed in some natural debris flows even of over-consolidated clay materials. Moreover, the accelerations and high velocities reached by the flow head in a short time appear to fit well with the required initial conditions of observed tsunamis as obtained from back-calculations. Investigations of high-speed video recordings of laboratory debris flows were combined with measurements of total and pore pressure. The results are pointing towards yet another important role of ambient water: Water that intrudes from the water cushion underneath the hydroplaning head and through cracks in the upper surface of the debris flow may drastically soften initially stiff clayey material in the "neck" of the flow, where significant stretching occurs due to the reduced friction at the bottom of the hydroplaning head. This self-reinforcing process may lead to the head separating from the main body and becoming an "outrunner" block as clearly observed in several natural debris flows. Comparison of laboratory flows with different material composition indicates a gradual transition from hydroplaning plug flows of stiff clay-rich material, with a very low suspension rate, to the strongly agitated flow of sandy materials that develop a pronounced turbidity current. Statistical analysis of the great number of distinguishable lobes in the Storegga slide complex reveals power-law scaling behavior of the runout distance with the release mass over many orders of magnitude. Mathematical flow models based on viscoplastic material behavior (e.g. BING) successfully reproduce the observed scaling behavior only for relatively small clay-rich debris flows while granular (frictional) models fail at all scales

  8. Simulating hydroplaning of submarine landslides by quasi 3D depth averaged finite element method

    Science.gov (United States)

    De Blasio, Fabio; Battista Crosta, Giovanni

    2014-05-01

    G.B. Crosta, H. J. Chen, and F.V. De Blasio Dept. Of Earth and Environmental Sciences, Università degli Studi di Milano Bicocca, Milano, Italy Klohn Crippen Berger, Calgary, Canada Subaqueous debris flows/submarine landslides, both in the open ocean as well as in fresh waters, exhibit extremely high mobility, quantified by a ratio between vertical to horizontal displacement of the order 0.01 or even much less. It is possible to simulate subaqueous debris flows with small-scale experiments along a flume or a pool using a cohesive mixture of clay and sand. The results have shown a strong enhancement of runout and velocity compared to the case in which the same debris flow travels without water, and have indicated hydroplaning as a possible explanation (Mohrig et al. 1998). Hydroplaning is started when the snout of the debris flow travels sufficiently fast. This generates lift forces on the front of the debris flow exceeding the self-weight of the sediment, which so begins to travel detached from the bed, literally hovering instead of flowing. Clearly, the resistance to flow plummets because drag stress against water is much smaller than the shear strength of the material. The consequence is a dramatic increase of the debris flow speed and runout. Does the process occur also for subaqueous landslides and debris flows in the ocean, something twelve orders of magnitude larger than the experimental ones? Obviously, no experiment will ever be capable to replicate this size, one needs to rely on numerical simulations. Results extending a depth-integrated numerical model for debris flows (Imran et al., 2001) indicate that hydroplaning is possible (De Blasio et al., 2004), but more should be done especially with alternative numerical methodologies. In this work, finite element methods are used to simulate hydroplaning using the code MADflow (Chen, 2014) adopting a depth averaged solution. We ran some simulations on the small scale of the laboratory experiments, and secondly

  9. 4D understanding of failures in soft sedimentary rocks using repetitive terrestrial stereo-photogrammetry: the case of the Rosselin deep-seated slope instability, Valais, Switzerland.

    Science.gov (United States)

    Travelletti, Julien; Monnet, Régis

    2014-05-01

    runout stage the highly dislocated mass almost instantaneously behaves as a flow as it gathers speed. The field observations, the geometry of the failure and the computed mobilized volumes were then used as input for runout modelling of further possible failure scenario using a depth-integrated approximation of the flow dynamics equations. Acknowledgment: the authors would like to acknowledge the municipality of Riddes and the "Services des Routes, Transports et Cours d'Eau" (SRTCE) canton of Valais, Switzerland for the financial support and the extensometers data.

  10. The Tancitaro Debris Avalanche: Characterization, propagation and modeling

    Science.gov (United States)

    Morelli, Stefano; Monroy, Victor Hugo Garduño; Gigli, Giovanni; Falorni, Giacomo; Rocha, Eleazar Arreygue; Casagli, Nicola

    2010-06-01

    The Tancitaro volcano (3860 m) is an andesitic-dacitic stratovolcano located in the western portion of the Trans-Mexican Volcanic Belt within the state of Michoacán (Mexico). The tectonic activity of this area has likely contributed to a large sector collapse of the volcano. The first findings of a multidisciplinary investigation into this debris avalanche are presented here. Geomorphological analyses, based on the interpretation of orthophotos, satellite imagery and on GIS elaborations, had the objective of determining the main morphometric features of the landslide. The collapse structure is an east-facing horseshoe-shaped crater (4 km wide and 5.3 km long), while the deposit forms a large fan that is 66 km long, covers an area of approximately 1155 km 2 and has an estimated volume of 18 km 3. Event volume was established by reconstructing the paleo-edifice in a GIS and taking into account volumetric expansion. Cross sections measured in the field were also used for this purpose. Field investigations also highlighted the presence of two texturally distinct units, which are referred to as the "block facies" and the "matrix facies", respectively. The first is responsible for the typical hummock morphologies found in the proximal area. A transitional zone contains a "mixed block and matrix facies" while in the distal portion blocks and megablocks, some of which have a jigsaw puzzle texture, gradually decrease in size until they disappear entirely. A number of matrix samples were collected to conduct direct shear tests, granulometric analyses and classification of the materials. The data and analyses described above were used to discuss the mechanism controlling the long runout of the avalanche. Based on the comparison between the Tancitaro debris avalanche and similar events we propose that mechanical fluidization was the mechanism responsible for the remarkable mobility of the landslide. The predisposing factors leading to the collapse were also considered. Field

  11. Field-trip guide for exploring pyroclastic density current deposits from the May 18, 1980, eruption of Mount St. Helens, Washington

    Science.gov (United States)

    Brand, Brittany D.; Pollock, Nicholas; Sarocchi, Damiano; Dufek, Josef; Clynne, Michael A.

    2017-07-05

    Pyroclastic density currents (PDCs) are one of the most dangerous phenomena associated with explosive volcanism. To help constrain damage potential, a combination of field studies, laboratory experiments, and numerical modeling are used to establish conditions that influence PDC dynamics and depositional processes, including runout distance. The objective of this field trip is to explore field relations that may constrain PDCs at the time of emplacement.The PDC deposits from the May 18, 1980, eruption of Mount St. Helens are well exposed along the steep flanks (10–30° slopes) and across the pumice plain (5–12° slopes) as far as 8 km north of the volcano. The pumice plain deposits represent deposition from a series of concentrated PDCs and are primarily thick (3–12 m), massive, and poorly sorted. In contrast, the steep east-flank deposits are stratified to cross-stratified, suggesting deposition from PDCs where turbulence strongly influenced transport and depositional processes.The PDCs that descended the west flank were largely nondepositional; they maintained a higher flow energy and carrying capacity than PDCs funneled through the main breach, as evidenced by the higher concentration of large blocks in their deposits. The PDC from the west flank collided with PDCs funneled through the breach at various points along the pumice plain. Evidence for flow collision will be explored and debated throughout the field trip.Evidence for substrate erosion and entrainment is found (1) along the steep eastern flank of the volcano, which has a higher degree of rough, irregular topography relative to the west flanks where PDCs were likely nonerosive, (2) where PDCs encountered debris-avalanche hummocks across the pumice plain, and (3) where PDCs eroded and entrained material deposited by PDCs produced during earlier phases of the eruption. Two features interpreted as large-scale (tens of meters wide) levees and a large (~200 m wide) channel scour-and-fill feature

  12. 基于水沙动力过程的泥石流阻塞大河模式及判据研究%Criterion and patterns of debris flow blocking big river based on water and sediment dynamic processes

    Institute of Scientific and Technical Information of China (English)

    刘翠容; 姚令侃; 陈春光; 杜翠

    2012-01-01

      According to the characters of the submerged disk and the density current,the runout equations of the debris flow in the water is obtained, and the equation of the head-water level is given by the broad-crested weir theory. Based on the dynamic equation of the debris flow at different slopes,water and sediment dynamic processes, and the interaction between barriers dam of debris flow and main river were considered,and a model of the runout distance of debris flow in big river was established. In view of the phenomenon that the material erosion is very serious when debris flowing into big river,the erosion coeffi⁃cient is obtaineding using the test dates of flume experiment. Based on the total amount equation of debris flow was blocking given by Bifan ZHOU, a modal of the total amount of the big river blocked by debris flow was considered in hight of the erosion coefficient. The criterion of debris flow blocking big river was presented in terms of dynamic process and total amount of debris flow.%  根据潜坝壅堵模式的特点,基于异重流理论,给出了泥石流龙头在清水中的运动方程,并提出了有坎宽顶模型的潜坝壅堵上游水位计算式。基于水沙动力过程,以泥石流在坡度变化沟道内的运动方程为基础,考虑堰塞坝和主河水流的相互作用,给出了泥石流在主河中运移距离的计算公式;鉴于泥石流堵塞大河过程中物质流失严重的现象,根据水槽实验数据确定了流失系数;以周必凡提出的泥石流堵断主河总量的计算公式为基础,提出了按流失系数加以修正的泥石流阻塞大河物质总量条件。从而建立了基于动力学方程、物质总量的泥石流阻塞大河综合判据。

  13. Debris-flow Dynamics Inferred From Aggregated Results of 28 Large-scale Experiments

    Science.gov (United States)

    Iverson, R. M.; Logan, M.; Lahusen, R. G.; Berti, M.

    2008-12-01

    Key features of debris-flow dynamics are revealed by identifying reproducible trends in data collected during 28 large-scale experiments with closely controlled initial and boundary conditions. In each experiment, 10 m3 of water-saturated sediment consisting mostly of sand and gravel discharges abruptly from behind a vertical headgate, descends a ~90 m concrete flume inclined 31 degrees, and forms a deposit on a nearly horizontal runout surface. The experiments are grouped into three sets of 8 to 11 replicates distinguished by differing mud contents (1% vs. 7% by dry weight) and basal boundary roughnesses (1 mm vs. 20 mm characteristic amplitude). Aggregation of sensor data from each set of replicates reveals universal patterns, as well as variances, in evolution of flow velocities, depths, basal normal stresses, and basal pore pressures. The patterns show that debris flows consistently develop blunt, coarse-grained, high-friction flow fronts pushed from behind by nearly liquefied, finer-grained debris. This flow architecture yields lobate deposits bounded by coarse-grained snouts and lateral levees. The aggregated data also show that imposed differences in basal boundary conditions and debris compositions produce systematic -- and sometimes surprising -- differences in flow dynamics and deposits. For example, flows on rough beds run out further than flows on smooth beds, despite the fact that flows on smooth beds attain greater velocities. This counterintuitive behavior results from enhanced grain-size segregation in the presence of a rough bed; segregation accentuates development of lateral levees that channelize flow and retard depletion of downstream momentum by lateral spreading. Another consistent finding is that flows with significant mud content are more mobile (attain greater velocities and runouts) than flows lacking much mud. This behavior is evident despite the fact that mud measurably increases the viscosity and yield strength of the fluid component

  14. Dynamic interaction of two-phase debris flow with pyramidal defense structures: An optimal strategy to efficiently protecting the desired area

    Science.gov (United States)

    Kattel, Parameshwari; Kafle, Jeevan; Fischer, Jan-Thomas; Mergili, Martin; Tuladhar, Bhadra Man; Pudasaini, Shiva P.

    2017-04-01

    In this work we analyze the dynamic interaction of two phase debris flows with pyramidal obstacles. To simulate the dynamic interaction of two-phase debris flow (a mixture of solid particles and viscous fluid) with obstacles of different dimensions and orientations, we employ the general two-phase mass flow model (Pudasaini, 2012). The model consists of highly non-linear partial differential equations representing the mass and momentum conservations for both solid and fluid. Besides buoyancy, the model includes some dominant physical aspects of the debris flows such as generalized drag, virtual mass and non-Newtonian viscous stress as induced by the gradient of solid-volume-fraction. Simulations are performed with high-resolution numerical schemes to capture essential dynamics, including the strongly re-directed flow with multiple stream lines, mass arrest and debris-vacuum generation when the rapidly cascading debris mass suddenly encounters the obstacle. The solid and fluid phases show fundamentally different interactions with obstacles, flow spreading and dispersions, run-out dynamics, and deposition morphology. A forward-facing pyramid deflects the mass wider, and a rearward-facing pyramid arrests a portion of solid-mass at its front. Our basic study reveals that appropriately installed obstacles, their dimensions and orientations have a significant influence on the flow dynamics, material redistribution and redirection. The precise knowledge of the change in dynamics is of great importance for the optimal and effective protection of designated areas along the mountain slopes and the runout zones. Further important results are, that specific installations lead to redirect either solid, or fluid, or both, in the desired amounts and directions. The present method of the complex interactions of real two-phase mass flows with the obstacles may help us to construct defense structures and to design advanced and physics-based engineering solutions for the prevention

  15. Large Rock-Slope Failures Impacting on Lakes - Event Reconstruction and Interaction Analysis in Two Alpine Regions Using Sedimentology and Geophysics

    Science.gov (United States)

    Knapp, S.; Anselmetti, F.; Gilli, A.; Krautblatter, M.; Hajdas, I.

    2016-12-01

    Massive rock-slope failures are responsible for more than 60% of all catastrophic landslides disasters. Lateglacial and Holocene rock-slope failures often occur as multistage failures, but we have only limited datasets to reconstruct detailed stages and still aim at improving our knowledge of mobility processes. In this context, studying lakes will become more and more important for two main reasons. On the one hand, the lake background sedimentation acts as a natural chronometer, which enables the stratigraphic positioning of events and helps to reconstruct the event history. This way we will be able to improve our knowledge on multistage massive rock-slope failures. On the other hand, climate warming forces us to face an increase of lakes forming due to glacial melting, leading to new hazardous landscape settings. We will be confronted with complex reaction chains and feedback loops related to rock-slope instability, stress adaptation, multistage rock-slope failures, lake tsunamis, entrainment of water and fines, and finally lubrication. As a result, in future we will have to deal more and more with failed rock material impacting on lakes with much longer runout-paths than expected, and which we have not been able to reconstruct in our models so far. Here we want to present the key findings of two of our studies on lake sediments related to large rock-slope failures: We used reflection seismic profiles and sediment cores for the reconstruction of the rockfall history in the landslide-dammed Lake Oeschinen in the Bernese Oberland, Switzerland, where we detected and dated ten events and correlated them to (pre)historical data. As a second project, we have been working on the mobility processes of the uppermost sediments deposited during the late event stadium of the Eibsee rock avalanche at Mount Zugspitze in the Bavarian Alps, Germany. In the reflection seismic profiles we detected sedimentary structures that show high levels of fluidization and thus would hint at

  16. Mechanical coupling between two innovative theories on erosion, transportation and phase-separation: Solving some long-standing problems in mass flows

    Science.gov (United States)

    Pudasaini, Shiva P.; Fischer, Jan-Thomas; Mergili, Martin

    2017-04-01

    Debris flows are gravity driven mixture flows of soil, sand, rock and water. The solid particles and viscous fluid governs the rheological properties, and their coupling significantly influences the dynamics. For example, debris flows can dramatically increase their volume and destructive potential, and become exceptionally mobile by entraining bed material. The mixture composition can evolve to strikingly change the spatial distribution of particles and fluid, and thus frictional and viscous resistance. So, erosion-deposition and phase-separation between solid and fluid, which strongly depend on material composition, play a critical role in debris flow dynamics. Proper understanding of these complex physical processes is very important in accurate description of impact forces, inundation areas, landscape evolution and developing reliable mitigation plans. Predicting the underlying processes of erosion, phase-separation and deposition in debris flow are long-standing challenges. However, due to lack of data and suitable models, there exists no runout prediction method that includes observed processes of erosion of dry and saturated beds, entrainment and diffusion of eroded material, grain sorting, phase-separation, levee/lobe formation and evolution of deposition patterns. Based on innovative mechanical models for erosion-deposition (Pudasaini and Fischer, 2016a) and phase-separation (Pudasaini and Fischer, 2016b) that explicitly consider changes in local flow compositions, and their basic/potential validations, we present a novel, unified, efficient and fully coupled solution method to these true multi-phase, three-dimensional mass flow problems. As debris flows are better described by a three-phase mixture that include viscous fluid, and fine and coarse grains as compared to often used single-phase models, we propose model extensions that consists of three-phases including yield strength. Thus, we present an advanced mass flow simulation model aiming to

  17. Probabilistic Rockfall Hazard Analysis in the area affect by the Christchurch Earthquakes, New Zealand

    Science.gov (United States)

    Frattini, P.; Lari, S.; Agliardi, F.; Crosta, G. B.; Salzmann, H.

    2012-04-01

    To limit damages to human lives and property in case of natural disasters, land planning and zonation, as well as the design of countermeasures, are fundamental tools, requiring however a rigorous quantitative risk analysis. As a consequence of the 3rd September 2010 (Mw 7.1) Darfield Earthquake, and the 22nd February (Mw 6.2), the 16th April 2011 (Mw 5.3) and the 13th June, 2011 (Mw 6.2) aftershock events, about 6000 rockfalls were triggered in the Port Hills of Christchurch, New Zealand. Five people were killed by falling rocks in the area, and several hundred homes were damaged or evacuated. In this work, we present a probabilistic rockfall hazard analysis for a small area located in the south-eastern slope of Richmond Hill (0.6 km2, Sumner, Christchurch, NZ). For the analysis, we adopted a new methodology (Probabilistic Rockfall Hazard Analysis, PRHA), which allows to quantify the exceedance probability for a given slope location of being affected by a rockfall event with a specific level of kinetic energy, integrating the contribution of different rockfall magnitude (volume) scenarios. The methodology requires the calculation of onset annual frequency, rockfall runout, and spatially-varying kinetic energy. Onset annual frequencies for different magnitude scenarios were derived from frequency-magnitude relationship adapted from the literature. The probability distribution of kinetic energy for a given slope location and volume scenario was obtained by rockfall runout modeling of non-interacting blocks through the 3D Hy-Stone simulation code. The reference simulation was calibrated by back-analysis of rockfall events occurred during the earthquake. For each rockfall magnitude scenario, 20 rockfall trajectories have been simulated for each source cell using stochastically variable values of restitution parameters. Finally, probabilistic analysis integrating over six rockfall magnitude scenarios (ranging from 0.001 m3 to 1000 m3) was carried out to produce

  18. Volcanic debris avalanche transport and emplacement: water content and fragmentation vs disaggregation

    Science.gov (United States)

    Roverato, Matteo

    2016-04-01

    Volcanic Debris Avalanches are voluminous, heterogeneous mass-flows of poorly sorted sediments (micron - 10's m) that move downslope under the effect of gravity. They travel with extremely high velocity for long distances with very potential high destructive power. These flows may reach initial velocities as high as 100m/s, travel for several tens of kilometers, and spread over broad sectors. They are commonly considered as inertial dry grain flows where particle-particle interaction can be within a frictional and/or collisional regime. It is largely assumed that fragmentation of particles within a debris avalanche occurs primarily at the moment of the edifice failure, due to sudden material decompression and dilation. Following failure, the dislodged mass starts to slide or glide downslope, and progressive disaggregation begins. Only minimal fragmentation is thought to occur during flow due to grain-grain contact. Thus, the main process responsible for generating an interclast matrix during transport is the disaggregation of already fractured clasts and megaclasts, particularly those that are already diamictons. However, data obtained from the Pungarehu volcanic debris avalanche deposit (VDAD) illustrate that fragmentation of intact rock may also occur during debris avalanche motion and through collisional and frictional grain-grain contacts experienced during long-runout flow. More, depending on their water and clay content, these granular and block-sliding flows may transform into a debris flow with distance from source, changing completely their flow behaviour and enhancing their run-out and hazard impacts. Pungarehu VDAD (ca. 25 Ka cal.) was emplaced by the largest known collapse of the Taranaki volcano (New Zealand) occurred near the Last Glacial Maximum (LGM), with snow and ice cover, fluids circulation, hydrothermal alteration and substantial groundwater present. This VDAD appears to encompass a range of flow behaviour from proximal unsaturated and unmixed

  19. Debris flow hazard mapping, Hobart, Tasmania, Australia

    Science.gov (United States)

    Mazengarb, Colin; Rigby, Ted; Stevenson, Michael

    2015-04-01

    constrained by aerial photographs to decade precision and many predate regional photography (pre 1940's). We have performed runout modelling, using 2D hydraulic modelling software (RiverFlow2D with Mud and Debris module), in order to calibrate our model against real events and gain confidence in the choice of parameters. Runout modelling was undertaken in valley systems with volumes calibrated to existing flood model likelihoods for each catchment. The hazard outputs from our models require developing a translation to hazard models used in Australia. By linking to flood mapping we aim to demonstrate to emergency managers where existing mitigation measures may be inadequate and how they can be adapted to address multiple hazards.

  20. The influence of slope-angle ratio on the dynamics of granular flows: insights from laboratory experiments

    Science.gov (United States)

    Sulpizio, R.; Castioni, D.; Rodriguez-Sedano, L. A.; Sarocchi, D.; Lucchi, F.

    2016-11-01

    Laboratory experiments on granular flows using natural material were carried out in order to investigate the behaviour of granular flows passing over a break in slope. Sensors in the depositional area recorded the flow kinematics, while video footage permitted reconstruction of the deposit formation, which allowed investigation of the deposit shape as a function of the change in slope. We defined the slope-angle ratio as the proportion between slope angle in the depositional area and that of the channel. When the granular flow encounters the break in slope part of the flow front forms a bouncing clast zone due to elastic impact with the expansion box floor. During this process, part of the kinetic energy of the dense granular flow is transferred to elutriating fine ash, which subsequently forms turbulent ash cloud accompanying the granular flow until it comes to rest. Morphometric analysis of the deposits shows that they are all elliptical, with an almost constant minor axis and a variable major axis. The almost constant value of the minor axis relates to the spreading angle of flow at the end of the channel, which resembles the basal friction angle of the material. The variation of the major axis is interpreted to relate to the effect of competing inertial and frictional forces. This effect also reflects the partitioning of centripetal and tangential velocities, which changes as the flow passes over the break in slope. After normalization, morphometric data provided empirical relationships that highlight the dependence of runout from the product of slope-angle ratio and the difference in height between granular material release and deposit. The empirical relationships were tested against the runouts of hot avalanches formed during the 1944 ad eruption at Vesuvius, with differences among actual and calculated values are between 1.7 and 15 %. Velocity measurements of laboratory granular flows record deceleration paths at different breaks in slope. When normalized

  1. The Rheology of Acoustically Fluidized Sand

    Science.gov (United States)

    Conrad, J. W.; Melosh, J.

    2013-12-01

    The collapse of large craters and the formation of central peaks and peak rings is well modeled by numerical computer codes that incorporate the acoustic fluidization mechanism to temporarily allow the fluid-like flow of rock debris immediately after crater excavation. Furthermore, long runout landslides require a similar mechanism to explain their almost frictionless movement, which is probably also a consequence of their granular composition coupled with internal vibrations. Many different investigators have now confirmed the ability of vibrations to fluidize granular materials. Yet it still remains to fully describe the rheology of vibrated sand as a function of stress, frequency and amplitude of the vibrations in the sand itself. We constructed a rotational viscometer to quantitatively investigate the relation between the stress and strain rate in a horizontal bed of strongly vibrated sand. In addition to the macroscopic stain rate, the amplitude and frequency of the vibrations produced by a pair of pneumatic vibrators were also measured with the aid of miniaturized piezoelectric accelerometers (B&K 4393) whose output was recorded on a digital storage oscilloscope. The initial gathering of the experimental data was difficult due to granular memory, but by having the sand compacted vibrationally for 8 minutes before each run the scatter of data was reduced and we were able to obtain consistent results. Nevertheless, our major source of uncertainty was variations in strain rate from run to run. We find that vibrated sand flows like a highly non-Newtonian fluid, in which the shear strain rate is proportional to stress to a power much greater than one, where the precise power depends on the amplitude and frequency of the applied vibrations. Rapid flow occurs at stresses less than half of the static yield stress (that is, the yield stress when no vibration is applied) when strong vibrations are present. For a Newtonian fluid, such as water, the relation between

  2. Developing an Experimental Simulation Method for Rock Avalanches: Fragmentation Behavior of Brittle Analogue Material

    Science.gov (United States)

    Thordén Haug, Øystein; Rosenau, Matthias; Leever, Karen; Oncken, Onno

    2013-04-01

    Gravitational mass movement on earth and other planets show a scale dependent behavior, of which the physics is not fully understood. In particular, the runout distance for small to medium sized landslides (volume granular material down a chute. Though such granular avalanche models provide important insights into avalanche dynamics, they imply that the material fully disintegrate instantaneously. Observations from nature, however, suggests that a transition from solid to "liquid" occurs over some finite distance downhill, critically controlling the mobility and energy budget of the avalanche. Few experimental studies simulated more realistically the material failing during sliding and those were realized in a labscale centrifuge, where the range of volumes/scales is limited. To develop a new modeling technique to study the scale dependent runout behavior of rock avalanches, we designed, tested and verified several brittle materials allowing fragmentation to occur under normal gravity conditions. According to the model similarity theory, the analogue material must behave dynamically similar to the rocks in natural rock avalanches. Ideally, the material should therefore deform in a brittle manner with limited elastic and ductile strains up to a certain critical stress, beyond which the material breaks and deforms irreversibly. According to scaling relations derived from dimensional analysis and for a model-to-prototype length ratio of 1/1000, the appropriate yield strength for an analogue material is in the order of 10 kPa, friction coefficient around 0.8 and stiffness in the order of MPa. We used different sand (garnet, quartz) in combination with different matrix materials (sugar, salt, starch, plaster) to cement it. The deformation behavior and strength of the samples was tested using triaxial compression tests at atmospheric confining pressures. Proper material properties were obtained using well-sorted, well-rounded, medium grained quartz sand with gypsum

  3. Insights into the October-November 2010 Gunung Merapi eruption (Central Java, Indonesia) from the stratigraphy, volume and characteristics of its pyroclastic deposits

    Science.gov (United States)

    Cronin, Shane J.; Lube, Gert; Dayudi, Devi S.; Sumarti, Sri; Subrandiyo, S.; Surono

    2013-07-01

    The 2010 eruption of Merapi was the second most deadly in the historic record of this volcano, claiming over 380 lives. By relating the observations of this eruption with detailed examination of deposit distribution, stratigraphy and sedimentology, a reconstruction of the properties of the pyroclastic density currents (PDCs) is presented, including the valley controlled block-and-ash flows (BAFs) and widespread, energetic pyroclastic surges. The distribution, volume and mobility characteristics of all types of PDC during the eruption sequence show evidence for levels of intensity unseen since the large-scale 1872 and 1930 eruption phases, especially during the climactic events of October 26 and November 5. Many tephra falls interbedded with PDC units show that most dome-collapse events occurred along with and between explosive vulcanian eruptions. The 2010 eruption produced very long-runout BAFs, reaching 16.1 km in the Kali Gendol on November 5. This runout could be explained by its large-volume (20 million m3), around 10 times that of previous Merapi BAFs during the last 130 years. Major avulsion of these dense BAFs to form overbank deposits became more common through the eruptive sequence as the valley was progressively filled with successive PDC deposits. Spreading avulsed BAFs were a particular hazard downstream of ~ 10 km where the landscape is less dissected. Less clear, however, is why pyroclastic surges extended up to 10 km from the vent on November 5 and > 6.4 km on October 26. These expanded much farther from BAF margins (~ 2 km) than ever seen before at Merapi. In one location they were decoupled from valley-centered BAFs with high momentum, traveling initially laterally across steep valley systems, before draining downslope. At this site, on the western side of the upper Gendol at around 3 km from source, surge decoupling was apparently exacerbated by upstream collision and deflection of high-flux, hot and gas-rich BAFs against the cliffs of Gunung

  4. Internal characteristics of refractive-index matched debris flows

    Science.gov (United States)

    Gollin, Devis; Bowman, Elisabeth; Sanvitale, Nicoletta

    2016-04-01

    Debris flows are channelized masses of granular material saturated with water that travel at high speeds downslope. Their destructive character represents a hazard to lives and properties, especially in regions of high relief and runoff. The characteristics that distinguish their heterogeneous, multi-phase, nature are numerous: non-uniform surge formation, particle size ranging from clay to boulders, flow segregation with larger particles concentrating at the flow front and fluid at the tail making the composition and volume of the bulk varying with time and space. These aspects render these events very difficult to characterise and predict, in particular in the area of the deposit spread or runout - zones which are generally of most interest in terms of human risk. At present, considerable gaps exist in our understanding of the flow dynamics of debris flows, which originates from their complex motion and relatively poor observations available. Flume studies offer the potential to examine in detail the behaviour of model debris flows, however, the opaque nature of these flows is a major obstacle in gaining insight of their internal behaviour. Measurements taken at the sidewalls may be poorly representative leading to incomplete or misleading results. To probe internally to the bulk of the flow, alternative, nonintrusive techniques can be used, enabling, for instance, velocities and solid concentrations within the flowing material to be determined. We present experimental investigations into polydisperse granular flows of spherical immersed particles down an inclined flume, with specific attention directed to their internal behavior. To this end, the refractive indices of solids and liquid are closely matched allowing the two phases to be distinguished. Measurements are then made internally at a point in the channel via Plane Laser Induced Fluorescence, Particle Tracking Velocimetry, PTV and Particle Image Velocimetry, PIV. The objective is to to increase our

  5. Emerging insights into the dynamics of submarine debris flows

    Directory of Open Access Journals (Sweden)

    A. Elverhøi

    2005-01-01

    Full Text Available Recent experimental and theoretical work on the dynamics of submarine debris flows is summarized. Hydroplaning was first discovered in laboratory flows and later shown to likely occur in natural debris flows as well. It is a prime mechanism for explaining the extremely long runout distances observed in some natural debris flows even of over-consolidated clay materials. Moreover, the accelerations and high velocities reached by the flow head in a short time appear to fit well with the required initial conditions of observed tsunamis as obtained from back-calculations. Investigations of high-speed video recordings of laboratory debris flows were combined with measurements of total and pore pressure. The results are pointing towards yet another important role of ambient water: Water that intrudes from the water cushion underneath the hydroplaning head and through cracks in the upper surface of the debris flow may drastically soften initially stiff clayey material in the 'neck' of the flow, where significant stretching occurs due to the reduced friction at the bottom of the hydroplaning head. This self-reinforcing process may lead to the head separating from the main body and becoming an 'outrunner' block as clearly observed in several natural debris flows. Comparison of laboratory flows with different material composition indicates a gradual transition from hydroplaning plug flows of stiff clay-rich material, with a very low suspension rate, to the strongly agitated flow of sandy materials that develop a pronounced turbidity current. Statistical analysis of the great number of distinguishable lobes in the Storegga slide complex reveals power-law scaling behavior of the runout distance with the release mass over many orders of magnitude. Mathematical flow models based on viscoplastic material behavior (e.g. BING successfully reproduce the observed scaling behavior only for relatively small clay-rich debris flows while granular (frictional models

  6. Clast comminution during pyroclastic density current transport: Mt St Helens

    Science.gov (United States)

    Dawson, B.; Brand, B. D.; Dufek, J.

    2011-12-01

    Volcanic clasts within pyroclastic density currents (PDCs) tend to be more rounded than those in fall deposits. This rounding reflects degrees of comminution during transport, which produces an increase in fine-grained ash with distance from source (Manga, M., Patel, A., Dufek., J. 2011. Bull Volcanol 73: 321-333). The amount of ash produced due to comminution can potentially affect runout distance, deposit sorting, the volume of ash lofted into the upper atmosphere, and increase internal pore pressure (e.g., Wohletz, K., Sheridan, M. F., Brown, W.K. 1989. J Geophy Res, 94, 15703-15721). For example, increased pore pressure has been shown to produce longer runout distances than non-comminuted PDC flows (e.g., Dufek, J., and M. Manga, 2008. J. Geophy Res, 113). We build on the work of Manga et al., (2011) by completing a pumice abrasion study for two well-exposed flow units from the May 18th, 1980 eruption of Mt St Helens (MSH). To quantify differences in comminution from source, sampling and the image analysis technique developed in Manga et al., 2010 was completed at distances proximal, medial, and distal from source. Within the units observed, data was taken from the base, middle, and pumice lobes within the outcrops. Our study is unique in that in addition to quantifying the degree of pumice rounding with distance from source, we also determine the possible range of ash sizes produced during comminution by analyzing bubble wall thickness of the pumice through petrographic and SEM analysis. The proportion of this ash size is then measured relative to the grain size of larger ash with distance from source. This allows us to correlate ash production with degree of rounding with distance from source, and determine the fraction of the fine ash produced due to comminution versus vent-fragmentation mechanisms. In addition we test the error in 2D analysis by completing a 3D image analysis of selected pumice samples using a Camsizer. We find that the roundness of PDC

  7. Description and analysis of the debris flows occurred during 2008 in the Eastern Pyrenees

    Directory of Open Access Journals (Sweden)

    M. Portilla

    2010-07-01

    Full Text Available Rainfall-triggered landslides taking place in the Spanish Eastern Pyrenees have usually been analysed on a regional scale. Most research focussed either on terrain susceptibility or on the characteristics of the critical rainfall, neglecting a detailed analysis of individual events. In contrast to other mountainous regions, research on debris flow has only been performed marginally and associated hazard has mostly been neglected.

    In this study, five debris flows, which occurred in 2008, are selected; and site specific descriptions and analysis regarding geology, morphology, rainfall data and runout were performed. The results are compared with worldwide data and some conclusions on hazard assessment are presented.

    The five events can be divided into two in-channel debris flows and three landslide-triggered debris flows. The in-channel generated debris flows exceeded 10 000 m3, which are unusually large mass movements compared to historic events which occurred in the Eastern Pyrenees. In contrast, the other events mobilised total volumes less than 2000 m3. The geomorphologic analysis showed that the studied events emphasize similar patterns when compared to published data focussing on slope angle in the initiation zone or catchment area.

    Rainfall data revealed that all debris flows were triggered by high intensity-short duration rainstorms during the summer season. Unfortunately, existing rainfall thresholds in the Eastern Pyrenees consider long-lasting rainfall, usually occurring in autumn/winter. Therefore, new thresholds should be established taking into account the rainfall peak intensity in mm/h, which seems to be a much more relevant factor for summer than the event's total precipitation.

    The runout analysis of the 2008 debris flows confirms the trend that larger volumes generally induce higher mobility. The numerical simulation of the Riu Runer event shows that its dynamic behaviour

  8. Trigger Analysis and Modelling of Very Large Debris Flows in Santa Teresa, Cusco, Southern Peru

    Science.gov (United States)

    Buis, Daniel; Huggel, Christian; Frey, Holger; Giráldez, Claudia; Rohrer, Mario; Christen, Marc; Portocarrero, César

    2014-05-01

    The Peruvian Andes have repeatedly been affected by large mass movements such as landslides, avalanches and debris flows. In 1998, two very large debris flows in the region of Machu Picchu (Sacsara and Ahobamba), southern Peru, destroyed the town of Santa Teresa, an important hydropower scheme and further infrastructure. The debris flows on the order of 5 to 25 million m3 volume rank among the largest recently observed events of this type worldwide. Despite their extreme dimensions, these events have not been studied in detail. An important limitation for more insight studies is the remote location of the mass flows and the very sparse information and data available for the study region. Neither triggering processes nor mass flow process characteristics have been understood to date. This study tries to fill some of these gaps in understanding that are critical to improved assessment of hazards and eventual risk reduction measures. For the trigger analysis we used data and information from field work, a limited number of ground based meteorological data, and complementary satellite derived data. Results indicate that in the case of the Sacsara event, heavy rainfall likely was a main trigger. For Ahobamba, antecedent rainfall as well as snow and ice melt leading to saturation of glacial sediments must have played an important role. Simulations with a dynamic debris flow model (RAMMS) allowed us to constrain a number of flow parameters such as flow height and velocity, runout distance and flow and deposition volumes. Strong surging flow behavior was detected, resulting in very large runout distance (exceeding 20 km); which rather depends on the largest single surge volume, not the total event volume. Based on the identification of potential mass flow sources we modeled a number of scenarios. The assessment of related hazards, including a preliminary hazard map, showed that several communities in catchments draining towards Santa Teresa are endangered by mass movements

  9. Transient 3D numerical simulations of column collapse and pyroclastic density current scenarios at Vesuvius

    Science.gov (United States)

    Esposti Ongaro, T.; Neri, A.; Menconi, G.; de'Michieli Vitturi, M.; Marianelli, P.; Cavazzoni, C.; Erbacci, G.; Baxter, P. J.

    2008-12-01

    Numerical simulations of column collapse and pyroclastic density current (PDC) scenarios at Vesuvius were carried out using a transient 3D flow model based on multiphase transport laws. The model describes the dynamics of the collapse as well as the effects of the 3D topography of the volcano on PDC propagation. Source conditions refer to a medium-scale sub-Plinian event and consider a pressure-balanced jet. Simulation results provide new insights into the complex dynamics of these phenomena. In particular: 1) column collapse can be characterized by different regimes, from incipient collapse to partial or nearly total collapse, thus confirming the possibility of a transitional field of behaviour of the column characterized by the contemporaneous and/or intermittent occurrence of ash fallout and PDCs; 2) the collapse regime can be characterized by its fraction of eruptive mass reaching the ground and generating PDCs; 3) within the range of the investigated source conditions, the propagation and hazard potential of PDCs appear to be directly correlated with the flow-rate of the mass collapsing to the ground, rather than to the collapse height of the column (this finding is in contrast with predictions based on the energy-line concept, which simply correlates the PDC runout and kinetic energy with the collapse height of the column); 4) first-order values of hazard variables associated with PDCs (i.e., dynamic pressure, temperature, airborne ash concentration) can be derived from simulation results, thereby providing initial estimates for the quantification of damage scenarios; 5) for scenarios assuming a location of the central vent coinciding with that of the present Gran Cono, Mount Somma significantly influences the propagation of PDCs, largely reducing their propagation in the northern sector, and diverting mass toward the west and southeast, accentuating runouts and hazard variables for these sectors; 6) the 2D modelling approximation can force an artificial

  10. Turbulent behaviour of non-cohesive sediment gravity flows at unexpectedly high flow density

    Science.gov (United States)

    Baker, Megan; Baas, Jaco H.; Malarkey, Jonathan; Kane, Ian

    2016-04-01

    Experimental lock exchange-type turbidity currents laden with non-cohesive silica-flour were found to be highly dynamic at remarkably high suspended sediment concentrations. These experiments were conducted to produce sediment gravity flows of volumetric concentrations ranging from 1% to 52%, to study how changes in suspended sediment concentration affects the head velocities and run-out distances of these flows, in natural seawater. Increasing the volumetric concentration of suspended silica-flour, C, up to C = 46%, within the flows led to a progressive increase in the maximum head velocity. This relationship suggests that suspended sediment concentration intensifies the density difference between the turbulent suspension and the ambient water, which drives the flow, even if almost half of the available space is occupied by sediment particles. However, from C = 46% to C = 52% a rapid reduction in the maximum head velocity was measured. It is inferred that at C = 46%, friction from grain-to-grain interactions begins to attenuate turbulence within the flows. At C > 46%, the frictional stresses become progressively more dominant over the turbulent forces and excess density, thus producing lower maximum head velocities. This grain interaction process started to rapidly reduce the run-out distance of the silica-flour flows at equally high concentrations of C ≥ 47%. All flows with C 9%. Yet, the critical flow concentration at which turbulence modulation commenced for these silica-flour laden flows appeared to be much higher. We suggest that Bagnold's 9% criterion cannot be applied to flows that carry fine-grained sediment, because turbulent forces are more important than dispersive forces, and frictional forces start to affect the flows only at concentrations just below the cubic packing density of spheres of C = 52%. These experimental results also imply that natural flows may be able to transport vast volumes of non-cohesive sediment with relative ease, especially

  11. Complete sequencing of an IncX3 plasmid carrying blaNDM-5 allele reveals an early stage in the dissemination of the blaNDM gene

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    M Krishnaraju

    2015-01-01

    Full Text Available Purpose: The aim of the present study was to perform molecular characterisation of the blaNDM plasmids and to understand the mechanism of its spread among pathogenic bacteria. Materials and Methods: Seventy-six non-repetitive carbapenem-resistant isolates which were collected during Nov 2011 to April 2013 from four hospitals in Chennai were analyzed for the presence of the blaNDM gene by PCR. Further, the genetic context of the blaNDM gene was analyzed by PCR specific to ISAba125 and bleMBL gene. One of the blaNDM plasmid was completely sequenced in the Illumina HiSeq platform. Results: Twenty-three isolates consisting of 8 Escherichia coli, 8 Klebsiella pneumoniae, 3 Klebsiella oxytoca, 3 Acinetobacter baumanii and 1 Pseudomonas aeruginosa were found to carry the blaNDM gene. In 18 isolates the blaNDM gene was associated with a bleMBL gene and the ISAba125 element. The complete sequencing of pNDM-MGR194 revealed an IncX3 replication type plasmid, with a length of 46,253 bp, an average GC content of 47% and 59 putative ORFs. The iteron region contained the blaNDM5 gene and the bleMBL , trpF and dsbC genes downstream and an IS5 inserted within the ISAba125 element upstream. Conclusion: This is the first report where the blaNDM gene insertion in a plasmid is not accompanied by other resistance gene determinants. These observations suggest that the IncX3 plasmid pNDM-MGR194 is an early stage in the dissemination of the blaNDM .

  12. A guild of 45 CRISPR-associated (Cas protein families and multiple CRISPR/Cas subtypes exist in prokaryotic genomes.

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    Daniel H Haft

    2005-11-01

    Full Text Available Clustered regularly interspaced short palindromic repeats (CRISPRs are a family of DNA direct repeats found in many prokaryotic genomes. Repeats of 21-37 bp typically show weak dyad symmetry and are separated by regularly sized, nonrepetitive spacer sequences. Four CRISPR-associated (Cas protein families, designated Cas1 to Cas4, are strictly associated with CRISPR elements and always occur near a repeat cluster. Some spacers originate from mobile genetic elements and are thought to confer "immunity" against the elements that harbor these sequences. In the present study, we have systematically investigated uncharacterized proteins encoded in the vicinity of these CRISPRs and found many additional protein families that are strictly associated with CRISPR loci across multiple prokaryotic species. Multiple sequence alignments and hidden Markov models have been built for 45 Cas protein families. These models identify family members with high sensitivity and selectivity and classify key regulators of development, DevR and DevS, in Myxococcus xanthus as Cas proteins. These identifications show that CRISPR/cas gene regions can be quite large, with up to 20 different, tandem-arranged cas genes next to a repeat cluster or filling the region between two repeat clusters. Distinctive subsets of the collection of Cas proteins recur in phylogenetically distant species and correlate with characteristic repeat periodicity. The analyses presented here support initial proposals of mobility of these units, along with the likelihood that loci of different subtypes interact with one another as well as with host cell defensive, replicative, and regulatory systems. It is evident from this analysis that CRISPR/cas loci are larger, more complex, and more heterogeneous than previously appreciated.

  13. [Current antibiotic resistance profile of uropathogenic Escherichia coli strains and therapeutic consequences].

    Science.gov (United States)

    El Bouamri, M C; Arsalane, L; Kamouni, Y; Yahyaoui, H; Bennouar, N; Berraha, M; Zouhair, S

    2014-12-01

    Urinary tract infections (UTI) are a very common reason for consultation and prescription in current practice. Excessive or inappropriate use of antibiotics in treating urinary tract infections is responsible for the emergence and spread of multiresistant uropathogenic bacteria. To evaluate the isolation frequency and antibiotic resistance of uropathogenic Escherichia coli strains isolated at the Marrakech region. We conducted a retrospective study over a period of three years (from 1st January 2010 to 31 December 2012). It included all non-redundant uropathogenic E. coli strains isolated in the microbiology laboratory of the Avicenne hospital of Marrakech, Morocco. During this study, 1472 uropathogenic enterobacteriaceae were isolated including 924 non-repetitive E. coli strains, an overall isolation frequency of 63%. Antibiotic resistance of isolated E. coli strains showed resistance rates to amoxicillin (65%), sulfamethoxazole-triméthropime (55%), amoxicillin-clavulanic acid (43%), ciprofloxacin (22%), gentamicin (14%), nitrofurans (11%), amikacin (8%) and fosfomycin (7%). The number of E. coli strains resistant to C3G by ESBL production was 67, an average frequency of 4.5% of all isolated uropathogenic enterobacteria. The associated antibiotic resistance in the case of ESBL-producing E. coli were 82% for ciprofloxacin, 76% for sulfamethozole trimethoprim, 66% for gentamicin and 56% for amikacin. No resistance to imipenem was recorded for the isolated E. coli strains, which represents an imipenem sensitivity of 100%. Antibiotic resistance of uropathogenic E. coli strains limits treatment options and therefore constitutes a real public health problem. The regular updating of antibiotic susceptibility statistics of E. coli strains allows a better adaptation of the probabilistic antibiotic therapy to local epidemiological data. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  14. First report of TEM-104-, SHV-99-, SHV-108-, and SHV-110-producing Klebsiella pneumoniae from Iran

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    Shahram Shahraki-Zahedani

    Full Text Available Abstract: INTRODUCTION: Extended-spectrum beta-lactamases (ESBLs are bacterial enzymes capable of hydrolyzing beta-lactams. The aim of this study was to describe the prevalence of TEM- and SHV-type ESBL-producing Klebsiella pneumoniae strains in Zahedan, Southeast Iran. METHODS: A total of 170 non-repetitive K. pneumoniae strains were collected from patients referred to three teaching hospitals of Zahedan. Antibiotic susceptibility testing was determined for 17 antibiotics using the Kirby-Bauer disc diffusion method. The frequency of ESBL-producing strains was calculated, and minimum inhibitory concentrations of ESBL-producing strains were determined for cefotaxime, ceftazidime, ceftriaxone, and cefpodoxime. The presence of bla TEM and bla SHV genes was tested in all ESBL-producing strains using polymerase chain reaction and DNA sequencing. RESULTS: Among the 170 K. pneumoniae clinical isolates, 55 (32.4% were ESBL producers; 92.7% (n=51 and 72.7% (n=40 of the isolates carried the bla SHV and bla TEM genes, respectively, and 67.3% (n=37 carried both genes. The sequencing results showed that all bla TEM types were bla TEM-1, except for two isolates that were bla TEM-104. The bla SHV types were bla SHV-1, bla SHV-11, bla SHV-12, bla SHV-99, bla SHV-108, and bla SHV-110. CONCLUSIONS: The percentage of bla TEM and bla SHV among ESBL-producing K. pneumoniae isolates from Zahedan is relatively high, indicating the need for further surveillance and consideration in antibiotic use. To the best of our knowledge, this is the first report of TEM-104-, SHV-99-, SHV-108-, and SHV-110-type ESBLs among clinical isolates of K. pneumoniae from Iran, and TEM-1, SHV-1, SHV-11, and SHV-12 appear to be the dominant ESBLs in this region.

  15. Molecular Characterization of Streptococcus agalactiae Causing Community- and Hospital-acquired Infections in Shanghai, China

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    Haoqin Jiang

    2016-08-01

    Full Text Available Streptococcus agalactiae, a colonizing agent in pregnant women and the main cause of neonatal sepsis and meningitis, has been increasingly associated with invasive disease in nonpregnant adults. We collected a total of 87 non-repetitive S. agalactiae isolates causing community-acquired (CA and hospital-acquired (HA infections in nonpregnant adults from a teaching hospital in Shanghai between 2009 and 2013. We identified and characterized their antibiotic resistance, sequence type (ST, serotype, virulence, and biofilm formation. The most frequent STs were ST19 (29.9%, ST23 (16.1%, ST12 (13.8%, and ST1 (12.6%. ST19 had significantly different distributions between CA- and HA-group B Streptococci (GBS isolates. The most frequent serotypes were III (32.2%, Ia (26.4%, V (14.9%, Ib (13.8%, and II (5.7%. Serotype III/ST19 was significantly associated with levofloxacin resistance in all isoates. The HA-GBS multidrug resistant rate was much higher than that of CA-GBS. Virulence genes pavA, cfb were found in all isolates. Strong correlations exist between serotype Ib (CA and HA and surface protein genes spb1 and bac, serotype III (HA and surface protein gene cps and GBS pilus cluster. The serotype, epidemic clone, PFGE-based genotype, and virulence gene are closely related between CA-GBS and HA-GBS, and certain serotypes and clone types were significantly associated with antibiotic resistance. However, CA-GBS and HA-GBS still had significant differences in their distribution of clone types, antibiotic resistance, and specific virulence genes, which may provide a basis for infection control.

  16. Task Dominance Determines Backward Inhibition in Task Switching

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    Kerstin Jost

    2017-05-01

    Full Text Available Switching between tasks is assumed to be accompanied by inhibiting currently irrelevant, but competing tasks. A dominant task that strongly interferes with performing a weaker task may receive especially strong inhibition. We tested this prediction by letting participants switch among three tasks that differ in dominance: a location discrimination task with strong stimulus–response bindings (responding with left-hand and right-hand button presses to stimuli presented left or right to the fixation cross was combined with a color/pattern and a shape discrimination task, for which stimulus–response mappings were arbitrary (e.g., left-hand button press mapped to a red stimulus. Across three experiments, the dominance of the location task was documented by faster and more accurate responses than in the other tasks. This even held for incompatible stimulus–response mappings (i.e., right-hand response to a left-presented stimulus and vice versa, indicating that set-level compatibility (i.e., “dimension overlap” was sufficient for making this location task dominant. As a behavioral marker for backward inhibition, we utilized n-2 repetition costs that are defined by higher reaction times for a switch back to a just abandoned and thus just inhibited task (ABA sequence than for a switch to a less recently inhibited task (CBA, n-2 non-repetition. Reliable n-2 task repetition costs were obtained for all three tasks. Importantly, these costs were largest for the location task, suggesting that inhibition indeed was stronger for the dominant task. This finding adds to other evidence that the amount of inhibition is adjusted in a context-sensitive way.

  17. Diversity and antibiotic resistance in Pseudomonas spp. from drinking water.

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    Vaz-Moreira, Ivone; Nunes, Olga C; Manaia, Célia M

    2012-06-01

    Pseudomonas spp. are common inhabitants of aquatic environments, including drinking water. Multi-antibiotic resistance in clinical isolates of P. aeruginosa is widely reported and deeply characterized. However, the information regarding other species and environmental isolates of this genus is scant. This study was designed based on the hypothesis that members of the genus Pseudomonas given their high prevalence, wide distribution in waters and genetic plasticity can be important reservoirs of antibiotic resistance in drinking water. With this aim, the diversity and antibiotic resistance phenotypes of Pseudomonas isolated from different drinking water sources were evaluated. The genotypic diversity analyses were based on six housekeeping genes (16S rRNA, rpoD, rpoB, gyrB, recA and ITS) and on pulsed field gel electrophoresis. Susceptibility to 21 antibiotics of eight classes was tested using the ATB PSE EU (08) and disk diffusion methods. Pseudomonas spp. were isolated from 14 of the 32 sampled sites. A total of 55 non-repetitive isolates were affiliated to twenty species. Although the same species were isolated from different sampling sites, identical genotypes were never observed in distinct types of water (water treatment plant/distribution system, tap water, cup fillers, biofilm, and mineral water). In general, the prevalence of antibiotic resistance was low and often the resistance patterns were related with the species and/or the strain genotype. Resistance to ticarcillin, ticarcillin with clavulanic acid, fosfomycin and cotrimoxazol were the most prevalent (69-84%). No resistance to piperacillin, levofloxacin, ciprofloxacin, tetracycline, gentamicin, tobramycin, amikacin, imipenem or meropenem was observed. This study demonstrates that Pseudomonas spp. are not so widespread in drinking water as commonly assumed. Nevertheless, it suggests that water Pseudomonas can spread acquired antibiotic resistance, preferentially via vertical transmission.

  18. Assessment of Industrial Exposure to Magnetic Fields (invited paper)

    Energy Technology Data Exchange (ETDEWEB)

    Chadwick, P

    1999-07-01

    Magnetic field strengths produced by industrial processes can be very large, but they often exhibit a marked spatial variation. Whilst there may be the potential for exposures of workers to be high, actual exposure will be determined to a great extent by working practices. Possible metrics for epidemiological studies might be based on the temporal variability of exposure as well as maximum operator exposure or time-weighted average exposure and, whilst it might be possible to estimate these quantities from spot magnetic field strength measurements and observed working practices, this might be very difficult to achieve in practice. An alternative would be the use of a logging dosemeter: this paper describes some of the results of exposure assessments carried out in industrial environments with a modified EMDEX II magnetic field dosemeter. Magnetic fields in industrial environments often have waveforms which are not purely sinusoidal. Distortion can be introduced by the magnetic saturation of transformer and motor cores, by rectification, by poor matching between oscillator circuits and loads and when thyristors are used to control power. The resulting repetitive but non-sinusoidal magnetic field waveforms can be recorded and analysed; the spectral data may be incorporated into possible exposure metrics. It is also important to ensure that measurement instrumentation is responding appropriately in a non-sinusoidal field and this can only be done if the spectral content of the field is characterised fully. Some non-sinusoidal magnetic field waveforms cannot be expressed as a harmonic series. Specialist instrumentation and techniques are needed to assess exposure to such fields. Examples of approaches to the assessment of exposure to repetitive and non-repetitive magnetic fields are also discussed. (author)

  19. Gene alterations at Drosophila inversion breakpoints provide prima facie evidence for natural selection as an explanation for rapid chromosomal evolution.

    Science.gov (United States)

    Guillén, Yolanda; Ruiz, Alfredo

    2012-02-01

    Chromosomal inversions have been pervasive during the evolution of the genus Drosophila, but there is significant variation between lineages in the rate of rearrangement fixation. D. mojavensis, an ecological specialist adapted to a cactophilic niche under extreme desert conditions, is a chromosomally derived species with ten fixed inversions, five of them not present in any other species. In order to explore the causes of the rapid chromosomal evolution in D. mojavensis, we identified and characterized all breakpoints of seven inversions fixed in chromosome 2, the most dynamic one. One of the inversions presents unequivocal evidence for its generation by ectopic recombination between transposon copies and another two harbor inverted duplications of non-repetitive DNA at the two breakpoints and were likely generated by staggered single-strand breaks and repair by non-homologous end joining. Four out of 14 breakpoints lay in the intergenic region between preexisting duplicated genes, suggesting an adaptive advantage of separating previously tightly linked duplicates. Four out of 14 breakpoints are associated with transposed genes, suggesting these breakpoints are fragile regions. Finally two inversions contain novel genes at their breakpoints and another three show alterations of genes at breakpoints with potential adaptive significance. D. mojavensis chromosomal inversions were generated by multiple mechanisms, an observation that does not provide support for increased mutation rate as explanation for rapid chromosomal evolution. On the other hand, we have found a number of gene alterations at the breakpoints with putative adaptive consequences that directly point to natural selection as the cause of D. mojavensis rapid chromosomal evolution.

  20. Gene alterations at Drosophila inversion breakpoints provide prima facie evidence for natural selection as an explanation for rapid chromosomal evolution

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    Guillén Yolanda

    2012-02-01

    Full Text Available Abstract Background Chromosomal inversions have been pervasive during the evolution of the genus Drosophila, but there is significant variation between lineages in the rate of rearrangement fixation. D. mojavensis, an ecological specialist adapted to a cactophilic niche under extreme desert conditions, is a chromosomally derived species with ten fixed inversions, five of them not present in any other species. Results In order to explore the causes of the rapid chromosomal evolution in D. mojavensis, we identified and characterized all breakpoints of seven inversions fixed in chromosome 2, the most dynamic one. One of the inversions presents unequivocal evidence for its generation by ectopic recombination between transposon copies and another two harbor inverted duplications of non-repetitive DNA at the two breakpoints and were likely generated by staggered single-strand breaks and repair by non-homologous end joining. Four out of 14 breakpoints lay in the intergenic region between preexisting duplicated genes, suggesting an adaptive advantage of separating previously tightly linked duplicates. Four out of 14 breakpoints are associated with transposed genes, suggesting these breakpoints are fragile regions. Finally two inversions contain novel genes at their breakpoints and another three show alterations of genes at breakpoints with potential adaptive significance. Conclusions D. mojavensis chromosomal inversions were generated by multiple mechanisms, an observation that does not provide support for increased mutation rate as explanation for rapid chromosomal evolution. On the other hand, we have found a number of gene alterations at the breakpoints with putative adaptive consequences that directly point to natural selection as the cause of D. mojavensis rapid chromosomal evolution.

  1. EFFECT OF VISIBLE RANGE ELECTROMAGNETIC RADIATIONS ON ESCHERICHIA COLI.

    Science.gov (United States)

    Azeemi, Samina T Yousuf; Shaukat, Saleem Farooq; Azeemi, Khawaja Shamsuddin; Khan, Idrees; Mahmood, Khalid; Naz, Farah

    2017-01-01

    Escherichia coli is the agent responsible for a range of clinical diseases. With emerging antimicrobial resistance, other treatment options including solar/photo-therapy are becoming increasingly common. Visible Range Radiation Therapy/Colour Therapy is an emerging technique in the field of energy/vibrational medicine that uses visible spectrum of Electromagnetic Radiations to cure different diseases. In this study, our goal was to understand the effect of Visible Range Electromagnetic Radiations on E. coli (in vitro) and therefore find out the most appropriate visible range radiation for the treatment of diseases caused by E. coli. A total of 6 non-repetitive E. coli isolates were obtained from urine samples obtained from hospitalized patients with UTI. Single colony of E. coli was inoculated in 3 ml of Lysogeny Broth (LB) and 40 μl of this E. coli suspension was poured into each of the plastic tubes which were then irradiated with six different wavelengths in the visible region (Table. 1) after 18 hours with one acting as a control. The Optical Densities of these irradiated samples were then measured. Furthermore, scanning electron microscopy (TEFCAN ZEGA3) was carried out. The analysis of the microscopic and SEM images of irradiated E. coli samples with six different visible range radiations is representative of The fact that E. coli responded differently to every applied radiation in the visible region and the most profound inhibitory effects were that of 538nm Visible Range Radiation (Green) which proved to be bactericidal and 590nm Visible Range Radiation (yellow) which was bacteriostatic. The enhanced growth of E. coli with varying degrees was clearly observed in 610nm (orange), 644nm (red), 464nm (Purple) and 453nm (blue). It can be concluded that 538nm (Green) and 590nm (Yellow) can effectively be used for treating E. coli borne diseases.

  2. Presence of qnr gene in Escherichia coli and Klebsiella pneumoniae resistant to ciprofloxacin isolated from pediatric patients in China

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    Wang Chuanqing

    2008-05-01

    Full Text Available Abstract Background Quinolone resistance in Enterobacteriaceae results mainly from mutations in type II DNA topoisomerase genes and/or changes in the expression of outer membrane and efflux pumps. Several recent studies have indicated that plasmid-mediated resistance mechanisms also play a significant role in fluoroquinolone resistance, and its prevalence is increasing worldwide. In China, the presence of the qnr gene in the clinical isolates of Enterobacteriaceae has been reported, but this transmissible quinolone resistance gene has not been detected in strains isolated singly from pediatric patients. Because quinolones associated with a variety of adverse side effects on children, they are not authorized for pediatric use. This study therefore aimed to investigate the presence of the qnr gene in clinical isolates of E. coli and K. pneumoniae from pediatric patients in China. Methods A total 213 of non-repetitive clinical isolates resistant to ciprofloxacin from E. coli and K. pneumoniae were collected from hospitalized patients at five children's hospital in Beijing, Shanghai, Guangzhou, and Chongqing. The isolates were screened for the plasmid-mediated quinolone resistance genes of qnrA, qnrB, and qnrS by PCR. Transferability was examined by conjugation with the sodium azide-resistant E. coli J53. All qnr-positive were analyzed for clonality by enterobacterial repetitive intergenic consensus (ERIC-PCR. Results The study found that 19 ciprofloxacin-resistant clinical isolates of E. coli and K. pneumoniae were positive for the qnr gene, and most of the qnr positive strains were ESBL producers. Conjugation experiments showed that quinolone resitance could be transferred to recipients. Apart from this, different DNA banding patterns were obtained by ERIC-PCR from positive strains, which means that most of them were not clonally related. Conclusion This report on transferable fluoroquinolone resistance due to the qnr gene among E. coli and K

  3. Molecular epidemiology and virulence factors of pyogenic liver abscess causing Klebsiella pneumoniae in China.

    Science.gov (United States)

    Luo, Y; Wang, Y; Ye, L; Yang, J

    2014-11-01

    The molecular epidemiology and prevalence of virulence factors of isolates from patients with Klebsiella pneumoniae liver abscess (KLA) in mainland China are unknown. Klebsiella pneumoniae isolates were obtained from drainage samples aseptically collected from patients with pyogenic liver abscess (PLA). The genetic similarity of KLA isolates was analyzed by pulsed-field gel electrophoresis. The hypermucoviscosity (HV) phenotype was identified by a positive string test. The K1 and K2 genotypes, the pLVPK-derived genetic loci, aerobactin gene, kfu and alls were detected by PCR amplification. The sequence types (STs) were identified by multilocus sequence typing. Among the 51 non-repetitive KLA isolates, 49 PFGE types have been identified. In total, 19 (37.2%) and 14 (27.4%) of the 51 KLA isolates belonged to clonal complex (CC) 23 and CC65, respectively, while the other 18 isolates (35.3%) were defined as other STs. CC23 consisted of only K1 strains, while CC65 included only K2 strains. All non-K1/K2 strains were classified as STs other than CC23 and CC65. Approximately 70.6% (36/51) of KLA isolates exhibited an HV phenotype. Both K1 and K2 isolates presented significantly higher prevalence of the pLVPK-derived loci than non-K1/K2 isolates. The K1 isolates had a significantly higher prevalence of the kfu and allS genes than K2 and non-K1/K2 isolates, while the K2 isolates exhibited higher repA prevalence than K1 and non-K1/K2 isolates. The majority of KLA isolates belonged to CC23K1 and CC65K2, while other STs with non-K1/K2 capsular types have also been identified. The virulent factors exhibited diverse distribution among the different clones of KLA isolates.

  4. Chromosome-wide mapping of DNA methylation patterns in normal and malignant prostate cells reveals pervasive methylation of gene-associated and conserved intergenic sequences

    Science.gov (United States)

    2011-01-01

    Background DNA methylation has been linked to genome regulation and dysregulation in health and disease respectively, and methods for characterizing genomic DNA methylation patterns are rapidly emerging. We have developed/refined methods for enrichment of methylated genomic fragments using the methyl-binding domain of the human MBD2 protein (MBD2-MBD) followed by analysis with high-density tiling microarrays. This MBD-chip approach was used to characterize DNA methylation patterns across all non-repetitive sequences of human chromosomes 21 and 22 at high-resolution in normal and malignant prostate cells. Results Examining this data using computational methods that were designed specifically for DNA methylation tiling array data revealed widespread methylation of both gene promoter and non-promoter regions in cancer and normal cells. In addition to identifying several novel cancer hypermethylated 5' gene upstream regions that mediated epigenetic gene silencing, we also found several hypermethylated 3' gene downstream, intragenic and intergenic regions. The hypermethylated intragenic regions were highly enriched for overlap with intron-exon boundaries, suggesting a possible role in regulation of alternative transcriptional start sites, exon usage and/or splicing. The hypermethylated intergenic regions showed significant enrichment for conservation across vertebrate species. A sampling of these newly identified promoter (ADAMTS1 and SCARF2 genes) and non-promoter (downstream or within DSCR9, C21orf57 and HLCS genes) hypermethylated regions were effective in distinguishing malignant from normal prostate tissues and/or cell lines. Conclusions Comparison of chromosome-wide DNA methylation patterns in normal and malignant prostate cells revealed significant methylation of gene-proximal and conserved intergenic sequences. Such analyses can be easily extended for genome-wide methylation analysis in health and disease. PMID:21669002

  5. Identification and characterization of methicillin-resistant Staphylococcus aureus (MRSA) from Austrian companion animals and horses.

    Science.gov (United States)

    Loncaric, Igor; Künzel, Frank; Licka, Theresia; Simhofer, Hubert; Spergser, Joachim; Rosengarten, Renate

    2014-01-31

    The aim of this study was to investigate the antimicrobial resistance, resistance gene patterns and genetic relatedness of a collection of Austrian methicillin-resistant Staphylococcus aureus (MRSA) isolates from companion animals and horses. A total of 89 non-repetitive MRSA isolates collected during routine veterinary microbiological examinations from April 2004 to the end of 2012, and one isolate from 2013 were used for this study. The presence of mecA and other resistance genes was confirmed by PCR. Isolates were genotyped by spa typing, two multiple-locus variable-number tandem repeat analyses (MLVA) analyses, SCCmec typing and multilocus sequence typing (MLST). PCR targeting Panton-Valentine leukocidin (PVL) and detection of staphylococcal enterotoxins (SE), toxic shock syndrome toxin (TSST) was performed using PCR assays. Antimicrobial susceptibility testing was performed. Five sequence types (STs-ST398, ST254, ST22, ST5 and ST1), SCCmec types II, IVa, V, and non-type-abele, 8 spa-types (t003, t011, t036, t127, t386, t1348, and t4450), and two isolates could not be assigned, 21 MLVA-14Orsay types Multiplex-PCR MLVA (mMLVA) displayed 17 different MLVA types. The present study is the most comprehensive dealing with MRSA from Austrian companion animals and horses. The results confirm that MRSA ST398 is present in a wide range of animal species and is predominant especially in horses. In other companion animals it is unclear whether the infections with the different MRSA isolates investigated in the present study truly represents a rare phenomenon or may be an emerging problem in companion animals.

  6. A study of biofilm production in clinical isolates of Staphylococci at a tertiary care hospital, Bangalore

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    Saroj Golia

    2015-02-01

    Full Text Available Background: The Biofilms are densely packed communities of microorganisms consisting of layers of cell clusters embedded in a matrix of extracellular polysaccharide called polysaccharide intercellular adhesin. This layer impedes the delivery of antibiotics to the biofilm forming microbial cells leading to emergence of drug resistance. Staphylococci are commensal bacteria on the human skin and mucous membranes. So it may be easily introduced as a contaminant during the surgical intervention. So, this study was conducted to identify the Biofilm producing strains from clinical isolates of Staphylococci. Methods: A total of 182 non-repetitive clinical strains of Staphylococci isolated from various clinical samples from Feb 2014 and #8211;Oct 2014 were included in the study. All the isolates were identified using standard microbiological procedures. All the samples were tested for biofilm production by modified Congo-red agar method and tube method. Results: Out of 182 samples that were included in the study, a total of 90 (49.45% samples showed biofilm formation of which 58 (75.32% were methicillin resistant and 32 (30.47% were methicillin sensitive. Also these strains were resistant to other antibiotics. Conclusion: Our study showed biofilm production by methicillin resistant strains which were also multidrug resistant. Treatment of methicillin resistant strains of Staphylococci is one of the most challenging task for the clinicians and the microbiologists. So they should be routinely screened for biofilm formation in order to prevent emergence and spread of multidrug resistant strains. [Int J Res Med Sci 2015; 3(2.000: 470-474

  7. Whole-genome and chromosome evolution associated with host adaptation and speciation of the wheat pathogen Mycosphaerella graminicola.

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    Eva H Stukenbrock

    2010-12-01

    Full Text Available The fungus Mycosphaerella graminicola has been a pathogen of wheat since host domestication 10,000-12,000 years ago in the Fertile Crescent. The wheat-infecting lineage emerged from closely related Mycosphaerella pathogens infecting wild grasses. We use a comparative genomics approach to assess how the process of host specialization affected the genome structure of M. graminicola since divergence from the closest known progenitor species named M. graminicola S1. The genome of S1 was obtained by Illumina sequencing resulting in a 35 Mb draft genome sequence of 32X. Assembled contigs were aligned to the previously sequenced M. graminicola genome. The alignment covered >90% of the non-repetitive portion of the M. graminicola genome with an average divergence of 7%. The sequenced M. graminicola strain is known to harbor thirteen essential chromosomes plus eight dispensable chromosomes. We found evidence that structural rearrangements significantly affected the dispensable chromosomes while the essential chromosomes were syntenic. At the nucleotide level, the essential and dispensable chromosomes have evolved differently. The average synonymous substitution rate in dispensable chromosomes is considerably lower than in essential chromosomes, whereas the average non-synonymous substitution rate is three times higher. Differences in molecular evolution can be related to different transmission and recombination patterns, as well as to differences in effective population sizes of essential and dispensable chromosomes. In order to identify genes potentially involved in host specialization or speciation, we calculated ratios of synonymous and non-synonymous substitution rates in the >9,500 aligned protein coding genes. The genes are generally under strong purifying selection. We identified 43 candidate genes showing evidence of positive selection, one encoding a potential pathogen effector protein. We conclude that divergence of these pathogens was

  8. Pigs in sequence space: A 0.66X coverage pig genome survey based on shotgun sequencing

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    Li Wei

    2005-05-01

    Full Text Available Abstract Background Comparative whole genome analysis of Mammalia can benefit from the addition of more species. The pig is an obvious choice due to its economic and medical importance as well as its evolutionary position in the artiodactyls. Results We have generated ~3.84 million shotgun sequences (0.66X coverage from the pig genome. The data are hereby released (NCBI Trace repository with center name "SDJVP", and project name "Sino-Danish Pig Genome Project" together with an initial evolutionary analysis. The non-repetitive fraction of the sequences was aligned to the UCSC human-mouse alignment and the resulting three-species alignments were annotated using the human genome annotation. Ultra-conserved elements and miRNAs were identified. The results show that for each of these types of orthologous data, pig is much closer to human than mouse is. Purifying selection has been more efficient in pig compared to human, but not as efficient as in mouse, and pig seems to have an isochore structure most similar to the structure in human. Conclusion The addition of the pig to the set of species sequenced at low coverage adds to the understanding of selective pressures that have acted on the human genome by bisecting the evolutionary branch between human and mouse with the mouse branch being approximately 3 times as long as the human branch. Additionally, the joint alignment of the shot-gun sequences to the human-mouse alignment offers the investigator a rapid way to defining specific regions for analysis and resequencing.

  9. The complete mitochondrial genome of the fall webworm, Hyphantria cunea (Lepidoptera: Arctiidae).

    Science.gov (United States)

    Liao, Fang; Wang, Lin; Wu, Song; Li, Yu-Ping; Zhao, Lei; Huang, Guo-Ming; Niu, Chun-Jing; Liu, Yan-Qun; Li, Ming-Gang

    2010-03-29

    The complete mitochondrial genome (mitogenome) of the fall webworm, Hyphantria cunea (Lepidoptera: Arctiidae) was determined. The genome is a circular molecule 15 481 bp long. It presents a typical gene organization and order for completely sequenced lepidopteran mitogenomes, but differs from the insect ancestral type for the placement of tRNA(Met). The nucleotide composition of the genome is also highly A + T biased, accounting for 80.38%, with a slightly positive AT skewness (0.010), indicating the occurrence of more As than Ts, as found in the Noctuoidea species. All protein-coding genes (PCGs) are initiated by ATN codons, except for COI, which is tentatively designated by the CGA codon as observed in other lepidopterans. Four of 13 PCGs harbor the incomplete termination codon, T or TA. All tRNAs have a typical clover-leaf structure of mitochondrial tRNAs, except for tRNA(Ser)(AGN), the DHU arm of which could not form a stable stem-loop structure. The intergenic spacer sequence between tRNA(Ser)(AGN) and ND1 also contains the ATACTAA motif, which is conserved across the Lepidoptera order. The H. cunea A+T-rich region of 357 bp is comprised of non-repetitive sequences, but harbors several features common to the Lepidoptera insects, including the motif ATAGA followed by an 18 bp poly-T stretch, a microsatellite-like (AT)(8) element preceded by the ATTTA motif, an 11 bp poly-A present immediately upstream tRNA(Met). The phylogenetic analyses support the view that the H. cunea is closerly related to the Lymantria dispar than Ochrogaster lunifer, and support the hypothesis that Noctuoidea (H. cunea, L. dispar, and O. lunifer) and Geometroidea (Phthonandria atrilineata) are monophyletic. However, in the phylogenetic trees based on mitogenome sequences among the lepidopteran superfamilies, Papillonoidea (Artogeia melete, Acraea issoria, and Coreana raphaelis) joined basally within the monophyly of Lepidoptera, which is different to the traditional classification.

  10. Whole Gene Capture Analysis of 15 CRC Susceptibility Genes in Suspected Lynch Syndrome Patients.

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    Anne M L Jansen

    Full Text Available Lynch Syndrome (LS is caused by pathogenic germline variants in one of the mismatch repair (MMR genes. However, up to 60% of MMR-deficient colorectal cancer cases are categorized as suspected Lynch Syndrome (sLS because no pathogenic MMR germline variant can be identified, which leads to difficulties in clinical management. We therefore analyzed the genomic regions of 15 CRC susceptibility genes in leukocyte DNA of 34 unrelated sLS patients and 11 patients with MLH1 hypermethylated tumors with a clear family history.Using targeted next-generation sequencing, we analyzed the entire non-repetitive genomic sequence, including intronic and regulatory sequences, of 15 CRC susceptibility genes. In addition, tumor DNA from 28 sLS patients was analyzed for somatic MMR variants.Of 1979 germline variants found in the leukocyte DNA of 34 sLS patients, one was a pathogenic variant (MLH1 c.1667+1delG. Leukocyte DNA of 11 patients with MLH1 hypermethylated tumors was negative for pathogenic germline variants in the tested CRC susceptibility genes and for germline MLH1 hypermethylation. Somatic DNA analysis of 28 sLS tumors identified eight (29% cases with two pathogenic somatic variants, one with a VUS predicted to pathogenic and LOH, and nine cases (32% with one pathogenic somatic variant (n = 8 or one VUS predicted to be pathogenic (n = 1.This is the first study in sLS patients to include the entire genomic sequence of CRC susceptibility genes. An underlying somatic or germline MMR gene defect was identified in ten of 34 sLS patients (29%. In the remaining sLS patients, the underlying genetic defect explaining the MMRdeficiency in their tumors might be found outside the genomic regions harboring the MMR and other known CRC susceptibility genes.

  11. Soft tissue and wound infections due to Enterococcus spp. among hospitalized trauma patients in a developing country

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    Nonika Rajkumari

    2014-01-01

    Full Text Available Soft tissue and wound infections due to Enterococcus spp. are increasing worldwide with current need to understand the epidemiology of the Enterococcal infections of wounds. Hence, we have looked into the distribution of Enterococcus spp. responsible for causing wound and soft tissue infections among trauma patients, its antibiotic resistance pattern and how it affects the length of hospital stay and mortality. A laboratory cum clinical-based study was performed over a period of 3 years at a level I trauma center in New Delhi, India. Patients with Enterococcal wound and soft tissue infections were identified using the hospital data base, their incidence of soft tissue/wound infections calculated, drug resistance pattern and their possible risk factors as well as outcomes analyzed. A total of 86 non-repetitive Enterococcus spp. was isolated of which E. faecium were maximally isolated 48 (56%. High level of resistance was seen to gentamicin HLAR in all the species of Enterococcus causing infections whereas a low level resistance to vancomycin and teicoplanin was observed among the isolates. Longer hospital stay, repeated surgical procedure, prior antibiotic therapy and ICU stay were observed to associate with increased morbidity (P < 0.05 and hence, more chances of infections with VRE among the trauma patients. The overall rate of wound and soft tissue infections with Enterococcus sp. was 8.6 per 1,000 admissions during the study period. Enterococcal wound infection is much prevalent in trauma care facilities especially in the ICUs. Here, a microbiologist can act as a sentinel, help in empirical therapeutic decisions and also in preventing such infections.

  12. G-quadruplex (G4) motifs in the maize (Zea mays L.) genome are enriched at specific locations in thousands of genes coupled to energy status, hypoxia, low sugar, and nutrient deprivation.

    Science.gov (United States)

    Andorf, Carson M; Kopylov, Mykhailo; Dobbs, Drena; Koch, Karen E; Stroupe, M Elizabeth; Lawrence, Carolyn J; Bass, Hank W

    2014-12-20

    The G-quadruplex (G4) elements comprise a class of nucleic acid structures formed by stacking of guanine base quartets in a quadruple helix. This G4 DNA can form within or across single-stranded DNA molecules and is mutually exclusive with duplex B-form DNA. The reversibility and structural diversity of G4s make them highly versatile genetic structures, as demonstrated by their roles in various functions including telomere metabolism, genome maintenance, immunoglobulin gene diversification, transcription, and translation. Sequence motifs capable of forming G4 DNA are typically located in telomere repeat DNA and other non-telomeric genomic loci. To investigate their potential roles in a large-genome model plant species, we computationally identified 149,988 non-telomeric G4 motifs in maize (Zea mays L., B73 AGPv2), 29% of which were in non-repetitive genomic regions. G4 motif hotspots exhibited non-random enrichment in genes at two locations on the antisense strand, one in the 5' UTR and the other at the 5' end of the first intron. Several genic G4 motifs were shown to adopt sequence-specific and potassium-dependent G4 DNA structures in vitro. The G4 motifs were prevalent in key regulatory genes associated with hypoxia (group VII ERFs), oxidative stress (DJ-1/GATase1), and energy status (AMPK/SnRK) pathways. They also showed statistical enrichment for genes in metabolic pathways that function in glycolysis, sugar degradation, inositol metabolism, and base excision repair. Collectively, the maize G4 motifs may represent conditional regulatory elements that can aid in energy status gene responses. Such a network of elements could provide a mechanistic basis for linking energy status signals to gene regulation in maize, a model genetic system and major world crop species for feed, food, and fuel.

  13. High throughput web inspection system using time-stretch real-time imaging

    Science.gov (United States)

    Kim, Chanju

    Photonic time-stretch is a novel technology that enables capturing of fast, rare and non-repetitive events. Therefore, it operates in real-time with ability to record over long period of time while having fine temporal resolution. The powerful property of photonic time-stretch has already been employed in various fields of application such as analog-to-digital conversion, spectroscopy, laser scanner and microscopy. Further expanding the scope, we fully exploit the time-stretch technology to demonstrate a high throughput web inspection system. Web inspection, namely surface inspection is a nondestructive evaluation method which is crucial for semiconductor wafer and thin film production. We successfully report a dark-field web inspection system with line scan speed of 90.9 MHz which is up to 1000 times faster than conventional inspection instruments. The manufacturing of high quality semiconductor wafer and thin film may directly benefit from this technology as it can easily locate defects with area of less than 10 microm x 10 microm where it allows maximum web flow speed of 1.8 km/s. The thesis provides an overview of our web inspection technique, followed by description of the photonic time-stretch technique which is the keystone in our system. A detailed explanation of each component is covered to provide quantitative understanding of the system. Finally, imaging results from a hard-disk sample and flexible films are presented along with performance analysis of the system. This project was the first application of time-stretch to industrial inspection, and was conducted under financial support and with close involvement by Hitachi, Ltd.

  14. Single-shot compressed ultrafast photography at one hundred billion frames per second

    Science.gov (United States)

    Gao, Liang; Liang, Jinyang; Li, Chiye; Wang, Lihong V.

    2014-12-01

    The capture of transient scenes at high imaging speed has been long sought by photographers, with early examples being the well known recording in 1878 of a horse in motion and the 1887 photograph of a supersonic bullet. However, not until the late twentieth century were breakthroughs achieved in demonstrating ultrahigh-speed imaging (more than 105 frames per second). In particular, the introduction of electronic imaging sensors based on the charge-coupled device (CCD) or complementary metal-oxide-semiconductor (CMOS) technology revolutionized high-speed photography, enabling acquisition rates of up to 107 frames per second. Despite these sensors' widespread impact, further increasing frame rates using CCD or CMOS technology is fundamentally limited by their on-chip storage and electronic readout speed. Here we demonstrate a two-dimensional dynamic imaging technique, compressed ultrafast photography (CUP), which can capture non-repetitive time-evolving events at up to 1011 frames per second. Compared with existing ultrafast imaging techniques, CUP has the prominent advantage of measuring an x-y-t (x, y, spatial coordinates; t, time) scene with a single camera snapshot, thereby allowing observation of transient events with temporal resolution as tens of picoseconds. Furthermore, akin to traditional photography, CUP is receive-only, and so does not need the specialized active illumination required by other single-shot ultrafast imagers. As a result, CUP can image a variety of luminescent--such as fluorescent or bioluminescent--objects. Using CUP, we visualize four fundamental physical phenomena with single laser shots only: laser pulse reflection and refraction, photon racing in two media, and faster-than-light propagation of non-information (that is, motion that appears faster than the speed of light but cannot convey information). Given CUP's capability, we expect it to find widespread applications in both fundamental and applied sciences, including biomedical

  15. Genomic characterization of large heterochromatic gaps in the human genome assembly.

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    Nicolas Altemose

    2014-05-01

    Full Text Available The largest gaps in the human genome assembly correspond to multi-megabase heterochromatic regions composed primarily of two related families of tandem repeats, Human Satellites 2 and 3 (HSat2,3. The abundance of repetitive DNA in these regions challenges standard mapping and assembly algorithms, and as a result, the sequence composition and potential biological functions of these regions remain largely unexplored. Furthermore, existing genomic tools designed to predict consensus-based descriptions of repeat families cannot be readily applied to complex satellite repeats such as HSat2,3, which lack a consistent repeat unit reference sequence. Here we present an alignment-free method to characterize complex satellites using whole-genome shotgun read datasets. Utilizing this approach, we classify HSat2,3 sequences into fourteen subfamilies and predict their chromosomal distributions, resulting in a comprehensive satellite reference database to further enable genomic studies of heterochromatic regions. We also identify 1.3 Mb of non-repetitive sequence interspersed with HSat2,3 across 17 unmapped assembly scaffolds, including eight annotated gene predictions. Finally, we apply our satellite reference database to high-throughput sequence data from 396 males to estimate array size variation of the predominant HSat3 array on the Y chromosome, confirming that satellite array sizes can vary between individuals over an order of magnitude (7 to 98 Mb and further demonstrating that array sizes are distributed differently within distinct Y haplogroups. In summary, we present a novel framework for generating initial reference databases for unassembled genomic regions enriched with complex satellite DNA, and we further demonstrate the utility of these reference databases for studying patterns of sequence variation within human populations.

  16. Polarization-fan high-order harmonics

    Science.gov (United States)

    Fleischer, Avner; Bordo, Eliyahu; Kfir, Ofer; Sidorenko, Pavel; Cohen, Oren

    2017-02-01

    We predict high-order harmonics in which the polarization within the spectral bandwidth of each harmonic varies with frequency continuously and significantly. For example, the interaction of counter-rotating circularly-polarized bichromatic drivers having close central frequencies with isotropic gas leads to the emission of polarization-fan harmonics where each harmonic in the spectrum has the following property: it is nearly circularly-polarized in one tail of the harmonic peak, linear in the center of the peak and nearly circular with the opposite helicity in the opposite tail. Also, we show that polarization-fan high harmonics with modulated ellipticity are obtained when elliptical drivers are used. Polarization-fan harmonics are obtained as a result of multiple (at least two) head-on recollisions of electrons with their parent ions occurring from different angles in a two-dimensional plane. The use of bichromatic drivers with close central frequencies largely preserves the single-cycle, single-atom and macroscopic physics of ‘ordinary’ high harmonic generation, where both the driver and high harmonics are linearly polarized. Thus, it should offer several attracting features, including (i) a direct route for extending the maximal photon energy of observed helical high harmonics to keV by using bichromatic drivers only in the mid-IR region and (ii) utilizing phase matching methods that were developed for ‘ordinary’ high harmonic generation driven by quasi-monochromatic pulses (e.g. pressure tuning phase matching). These polarization-fan harmonics may be utilized for exploring non-repetitive ultrafast chiral phenomena, e.g. dynamics of magnetic domains, in a single shot.

  17. Gelotophobia and the Challenges of Implementing Laughter into Virtual Agents Interactions

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    Willibald F. Ruch

    2014-11-01

    Full Text Available This study investigated which features of avatar laughter are perceived threatening for individuals with a fear of being laughed at (gelotophobia, and individuals with no gelotophobia. Laughter samples were systematically varied (e.g., intensity, laughter pitch, and energy for the voice, intensity of facial actions of the face in three modalities: animated facial expressions, synthesized auditory laughter vocalizations, and motion capture generated puppets displaying laughter body movements. In the online study 123 adults completed, the GELOPH (Ruch and Proyer, 2008 and rated randomly presented videos of the three modalities for how malicious, how friendly, how real the laughter was (0 not at all to 8 extremely. Additionally, an open question asked which markers led to the perception of friendliness/maliciousness. The current study identified features in all modalities of laughter stimuli that were perceived as malicious in general, and some that were gelotophobia specific. For facial expressions of avatars, medium intensity laughs triggered highest maliciousness in the gelotophobes. In the auditory stimuli, the fundamental frequency modulations and the variation in intensity were indicative of maliciousness. In the body, backwards and forward movements and rocking vs. jerking movements distinguished the most malicious from the least malicious laugh. From the open answers the shape and appearance of the lips curling induced feelings that the expression was malicious for non-gelotophobes and that the movement round the eyes, elicited the face to appear as friendly. This was opposite for gelotophobes. Gelotophobia savvy avatars should be of high intensity, containing lip and eye movements and be fast, non-repetitive voiced vocalization, variable and of short duration. It should not contain any features that indicate a down-regulation in the voice or body, or indicate voluntary/cognitive modulation.

  18. CASFISH: CRISPR/Cas9-mediated in situ labeling of genomic loci in fixed cells.

    Science.gov (United States)

    Deng, Wulan; Shi, Xinghua; Tjian, Robert; Lionnet, Timothée; Singer, Robert H

    2015-09-22

    Direct visualization of genomic loci in the 3D nucleus is important for understanding the spatial organization of the genome and its association with gene expression. Various DNA FISH methods have been developed in the past decades, all involving denaturing dsDNA and hybridizing fluorescent nucleic acid probes. Here we report a novel approach that uses in vitro constituted nuclease-deficient clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated caspase 9 (Cas9) complexes as probes to label sequence-specific genomic loci fluorescently without global DNA denaturation (Cas9-mediated fluorescence in situ hybridization, CASFISH). Using fluorescently labeled nuclease-deficient Cas9 (dCas9) protein assembled with various single-guide RNA (sgRNA), we demonstrated rapid and robust labeling of repetitive DNA elements in pericentromere, centromere, G-rich telomere, and coding gene loci. Assembling dCas9 with an array of sgRNAs tiling arbitrary target loci, we were able to visualize nonrepetitive genomic sequences. The dCas9/sgRNA binary complex is stable and binds its target DNA with high affinity, allowing sequential or simultaneous probing of multiple targets. CASFISH assays using differently colored dCas9/sgRNA complexes allow multicolor labeling of target loci in cells. In addition, the CASFISH assay is remarkably rapid under optimal conditions and is applicable for detection in primary tissue sections. This rapid, robust, less disruptive, and cost-effective technology adds a valuable tool for basic research and genetic diagnosis.

  19. Single-shot compressed ultrafast photography at one hundred billion frames per second.

    Science.gov (United States)

    Gao, Liang; Liang, Jinyang; Li, Chiye; Wang, Lihong V

    2014-12-04

    The capture of transient scenes at high imaging speed has been long sought by photographers, with early examples being the well known recording in 1878 of a horse in motion and the 1887 photograph of a supersonic bullet. However, not until the late twentieth century were breakthroughs achieved in demonstrating ultrahigh-speed imaging (more than 10(5) frames per second). In particular, the introduction of electronic imaging sensors based on the charge-coupled device (CCD) or complementary metal-oxide-semiconductor (CMOS) technology revolutionized high-speed photography, enabling acquisition rates of up to 10(7) frames per second. Despite these sensors' widespread impact, further increasing frame rates using CCD or CMOS technology is fundamentally limited by their on-chip storage and electronic readout speed. Here we demonstrate a two-dimensional dynamic imaging technique, compressed ultrafast photography (CUP), which can capture non-repetitive time-evolving events at up to 10(11) frames per second. Compared with existing ultrafast imaging techniques, CUP has the prominent advantage of measuring an x-y-t (x, y, spatial coordinates; t, time) scene with a single camera snapshot, thereby allowing observation of transient events with temporal resolution as tens of picoseconds. Furthermore, akin to traditional photography, CUP is receive-only, and so does not need the specialized active illumination required by other single-shot ultrafast imagers. As a result, CUP can image a variety of luminescent--such as fluorescent or bioluminescent--objects. Using CUP, we visualize four fundamental physical phenomena with single laser shots only: laser pulse reflection and refraction, photon racing in two media, and faster-than-light propagation of non-information (that is, motion that appears faster than the speed of light but cannot convey information). Given CUP's capability, we expect it to find widespread applications in both fundamental and applied sciences, including

  20. Specification and resolution of complex manipulation tasks. Application to remote robots tele-programming; Specification et resolution de taches de manipulation complexes. Application a la teleprogrammation de robots distants

    Energy Technology Data Exchange (ETDEWEB)

    Piccin, O

    1995-11-15

    The work presented in this thesis comes within the scope of remote manipulation with restricted communication properties between the operator and the remote site. This context renders traditional tele-operation infeasible. To enhance the autonomy of the remote manipulator, it is necessary to reason on a model of the robot and its workspace. However, discrepancies between the real world and its representation require calibration capabilities to identify both position and size of objects interacting with the robot. Moreover, the non-repetitiveness and complexity of the tasks demand that the specification system remains easy to re-program and capable of treating a wide range of problems. The proposed constraint-based approach permits the specification of complex manipulation tasks in which tasks' objectives are expressed in terms of mobilities and contact relationships to achieve or maintain between parts. The resulting constraint relationships are then treated by a numerical solver based on a Newton-Raphson scheme. An enhanced robustness has been achieved through a dynamic management of equations' conditioning. This enables the system to choose automatically for the most appropriate resolution scenario. The first main class of applications is complex motion generation for any kind of robotic mechanisms possibly including redundancy. Constraints setting can also be exploited to realize local obstacle avoidance. The proposed approach makes it possible to deal with calibration tasks within the same framework. This constitutes an essential feature in the context of remote manipulation where models are un-precisely known. Lastly, a weld line inspection experiment performed on a real manipulator allows us to put forward a strategy for robotic task performance at a remote location. (author)

  1. Characterization of simple sequence repeats (SSRs from Phlebotomus papatasi (Diptera: Psychodidae expressed sequence tags (ESTs

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    Hamarsheh Omar

    2011-09-01

    Full Text Available Abstract Background Phlebotomus papatasi is a natural vector of Leishmania major, which causes cutaneous leishmaniasis in many countries. Simple sequence repeats (SSRs, or microsatellites, are common in eukaryotic genomes and are short, repeated nucleotide sequence elements arrayed in tandem and flanked by non-repetitive regions. The enrichment methods used previously for finding new microsatellite loci in sand flies remain laborious and time consuming; in silico mining, which includes retrieval and screening of microsatellites from large amounts of sequence data from sequence data bases using microsatellite search tools can yield many new candidate markers. Results Simple sequence repeats (SSRs were characterized in P. papatasi expressed sequence tags (ESTs derived from a public database, National Center for Biotechnology Information (NCBI. A total of 42,784 sequences were mined, and 1,499 SSRs were identified with a frequency of 3.5% and an average density of 15.55 kb per SSR. Dinucleotide motifs were the most common SSRs, accounting for 67% followed by tri-, tetra-, and penta-nucleotide repeats, accounting for 31.1%, 1.5%, and 0.1%, respectively. The length of microsatellites varied from 5 to 16 repeats. Dinucleotide types; AG and CT have the highest frequency. Dinucleotide SSR-ESTs are relatively biased toward an excess of (AXn repeats and a low GC base content. Forty primer pairs were designed based on motif lengths for further experimental validation. Conclusion The first large-scale survey of SSRs derived from P. papatasi is presented; dinucleotide SSRs identified are more frequent than other types. EST data mining is an effective strategy to identify functional microsatellites in P. papatasi.

  2. Retrospective drug utilization review: impact of pharmacist interventions on physician prescribing

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    Angalakuditi M

    2011-06-01

    Full Text Available Mallik Angalakuditi1, Joseph Gomes21Georgia State University, Atlanta, GA, USA; 2Baxter Health Care, Deerfield, IL, USAObjectives: To evaluate the impact of retrospective drug utilization review (RDUR, pharmacist’s interventions on physician prescribing, and the level of spillover effect on future prescriptions following the intervention.Methods: A retrospective case–control study was conducted at a pharmacy benefits management company using the available prescription data from April 2004 to August 2005. RDUR conflicts evaluated and intervened by a clinical pharmacist served as a case group, whereas conflicts that were not evaluated and intervened by a clinical pharmacist served as a control group.Results: A total of 40,284 conflicts in cases and 13,044 in controls were identified. For cases, 32,780 interventions were considered nonrepetitive, and 529 were repetitive. There were 22,870 physicians in cases that received intervention letters and 2348 physicians in the control group that would have received intervention letters during the study period. Each physician received on average 1.4 interventions for cases vs 3.0 for controls. Among the case physicians who were intervened during the study period, 2.2% (505 were involved in a repeated intervention vs 18.2% (428 in controls (P < 0.001, which is an eight-fold difference. The most common conflict intervened on in cases was therapeutic appropriateness (8277, 25.3%, and for controls it was drug–drug interactions (1796, 25.4%. The overall interventional spillover effect in cases was 98.4% vs 89.4% in controls (P = 0.01.Conclusion: RDUR is an effective interventional program which results in decreased numbers of interventions per physician and provides a significant impact on future prescribing habits.Keywords: pharmacy management, spillover effect, RDUR, DUR

  3. Molecular Epidemiology and Antimicrobial Susceptibility of Clostridium difficile Isolates from a University Teaching Hospital in China

    Science.gov (United States)

    Cheng, Jing-Wei; Xiao, Meng; Kudinha, Timothy; Kong, Fanrong; Xu, Zhi-Peng; Sun, Lin-Ying; Zhang, Li; Fan, Xin; Xie, Xiu-Li; Xu, Ying-Chun

    2016-01-01

    While the developed world has seen a significant increase in the number of scientific articles on Clostridium difficile infection (CDI), the developing world still lags behind on this subject due to limited laboratory capacity, low awareness, and limited surveillance of this problem. As such, CDI is considered a neglected but potentially huge problem in developing countries. The major aim of this study was to systemically evaluate the utility of several molecular typing tools for CDI, including their relevance in epidemiological studies in developing countries such as China. A total of 116 non-repetitive toxigenic C. difficile isolates from Chinese patients, were studied. The isolates comprised 83 (71.6%) A+B+CDT- isolates, 27 (23.3%) A-B+CDT- isolates, and 6 (5.1%) A+B+CDT+ isolates. Typing methods evaluated included multilocus variable-number tandem-repeat analysis, PCR ribotyping, multilocus sequence typing, and sequencing of slpA and tcdC genes, which identified 113, 30, 22, 18, and 8 genotypes each and exhibited discriminatory powers of 0.999, 0.916, 0.907, 0.883, and 0.765, respectively. Compared to A+B+ strains, A-B+ strains exhibited higher prevalence of drug resistance to clindamycin, erythromycin, levofloxacin, rifampicin, rifaximin, and tetracycline. Furthermore, drug resistance rates of strains with different PCR ribotypes differed, supporting the importance of molecular typing in management and control of CDI. Based on our earlier suggestion to improve the diagnostic laboratory capacity of CDI in developing countries, setting up efficient surveillance programs complemented by relevant molecular typing methods is warranted.

  4. A Guild of 45 CRISPR-Associated (Cas Protein Families and Multiple CRISPR/Cas Subtypes Exist in Prokaryotic Genomes.

    Directory of Open Access Journals (Sweden)

    2005-11-01

    Full Text Available Clustered regularly interspaced short palindromic repeats (CRISPRs are a family of DNA direct repeats found in many prokaryotic genomes. Repeats of 21-37 bp typically show weak dyad symmetry and are separated by regularly sized, nonrepetitive spacer sequences. Four CRISPR-associated (Cas protein families, designated Cas1 to Cas4, are strictly associated with CRISPR elements and always occur near a repeat cluster. Some spacers originate from mobile genetic elements and are thought to confer "immunity" against the elements that harbor these sequences. In the present study, we have systematically investigated uncharacterized proteins encoded in the vicinity of these CRISPRs and found many additional protein families that are strictly associated with CRISPR loci across multiple prokaryotic species. Multiple sequence alignments and hidden Markov models have been built for 45 Cas protein families. These models identify family members with high sensitivity and selectivity and classify key regulators of development, DevR and DevS, in Myxococcus xanthus as Cas proteins. These identifications show that CRISPR/cas gene regions can be quite large, with up to 20 different, tandem-arranged cas genes next to a repeat cluster or filling the region between two repeat clusters. Distinctive subsets of the collection of Cas proteins recur in phylogenetically distant species and correlate with characteristic repeat periodicity. The analyses presented here support initial proposals of mobility of these units, along with the likelihood that loci of different subtypes interact with one another as well as with host cell defensive, replicative, and regulatory systems. It is evident from this analysis that CRISPR/cas loci are larger, more complex, and more heterogeneous than previously appreciated.

  5. High-level Multi-Resistant and Virulent Escherichia coli in Abeokuta, Nigeria.

    Science.gov (United States)

    Akinduti, Paul Akinniyi; Aboderin, Bukola W; Oloyede, Rasaq; Ogiogwa, Joseph I; Motayo, Babatunde O; Ejilude, Oluwaseun

    2016-01-01

    Multi-resistant Escherichia coli (E. coli) strains co-harboring virulence genes is a cause of high morbidity in Abeokuta, Nigeria. This study was designed to determine some virulent factors among enteropathogenic E. coli in Abeokuta, Nigeria. Approximately non-repetitive 102 isolates of E. coli were recovered from clinical samples from two health facilities in Abeokuta. Biotyping using API and antibiotic susceptibility was determined, and eae and flic genes were assayed by PCR. Antibiotic resistance relatedness was performed by DendroUPGMA. Results showed that 48.0% and 52.0 % were intestinal and extra-intestinal E. coli, ampicillin recorded 100% resistance, amoxycilli/clavulanic acid 64.7%, cotrimoxazole 57.8% and 56.8% resistance against cefotaxime, at MIC >16 ug/mL, 100%, 57.8%, and 50% have MIC50 to ampicillin, tetracycline, and ceftazidime, while 74.5% and 48.0% have MIC90 to ampicillin and ceftazidime. Significant rates of 4.9%, 7.8%, and 9.8% flic, eae, and flic/eae genes were found in intestinal isolates, while 2.9%, 2.0%, and 3.9% were found in extra-intestinal (P < 0.05). Two major clades of the resistant isolates reveal significant antibiotic relatedness among intestinal and extra-intestinal isolates, at 54% resistance similarities with very high multi-antibiotic resistance index of 1.0 (MARI). A high rate of undetected virulent E. coli pathotypes with high resistance could trigger unprecedented morbidity and mortality, mostly among children and the elderly.

  6. Population structure analyses of Staphylococcus aureus at Tygerberg Hospital, South Africa, reveals a diverse population, a high prevalence of Panton-Valentine leukocidin genes, and unique local methicillin-resistant S. aureus clones.

    Science.gov (United States)

    Oosthuysen, W F; Orth, H; Lombard, C J; Sinha, B; Wasserman, E

    2014-07-01

    Studies reporting on the population structure of Staphylococcus aureus in South Africa have focused only on methicillin-resistant S. aureus (MRSA). This study describes the population structure of S. aureus, including methicillin-susceptible S. aureus (MSSA) isolated from patients at Tygerberg Academic Hospital, Western Cape province. Pulsed-field gel electrophoresis (PFGE), detection of Panton-Valentine leukocidin (PVL), spa typing, multilocus sequence typing (MLST), agr typing and SCCmec typing were used to characterize strains. Of 367 non-repetitive S. aureus isolates collected over a period of 1 year, 56 (15.3%) were MRSA. Skin and soft tissue infections were the most frequent source (54.8%), followed by bone and joint (15.3%) and respiratory tract infections (7.7%). For strain typing, PFGE was the most discriminative method, and resulted in 31 pulsotypes (n = 345, 94.0%), as compared with 16 spa clonal complexes (CCs) (n = 344, 93.4%). Four MLST CCs were identified after eBURST of sequence types (STs) of selected isolates. One hundred and sixty isolates (MSSA, n = 155, 42.2%) were PVL-positive, and agr types I-IV and SCCmec types I-V were identified. Our S. aureus population consisted of genotypically diverse strains, with PVL being a common characteristic of MSSA. MSSA and MRSA isolates clustered in different clones. However, the dominant MRSA clone (ST612) also contained an MSSA isolate, and had a unique genotype. Common global epidemic MRSA clones, such as ST239-MRSA-III and ST36-MRSA-II, were identified. A local clone, ST612-MRSA-IV, was found to be the dominant MRSA clone. © 2013 The Authors Clinical Microbiology and Infection © 2013 European Society of Clinical Microbiology and Infectious Diseases.

  7. Legal consequences for torture in children cases: the Gomez Paquiyauri Brothers vs Peru case.

    Science.gov (United States)

    Tinta, Monica Feria

    2009-01-01

    The Gomez Paquiyauri Brothers case, before the Inter-American Court of Human Rights, was the first international case concerning the protection of children in the context of armed conflict where an international court stated the law concerning the duties of States towards children even in the context of war, and provided for reparations. As such it represents a landmark decision. The case arose from the illegal detention, torture and extrajudicial execution of two minors, Emilio and Rafael Gomez Paquiyauri, at the hands of Peruvian Police in 1991, under the Fujimori Administration at a time when the internal war in Peru was at its peak. Unlike most cases coming to the jurisdiction of the Inter-American Court, the case had been subject to domestic criminal investigations that had led to the convictions of two low ranking policemen. Yet a more subtle pattern of impunity lied at the root of the case. Torture had been denied by the State, and the prosecutions of low ranking policemen had intended to cover up the responsibility of those who ordered a policy of torture and executions (including the existence of secret codes for the torture and elimination of suspects of "terrorism") during the years of the internal armed conflict in Peru. The joint work of legal and medical expertise in the litigation of the case permitted the establishment of the facts and the law, obtaining an award of 740,500 dollars for the victims and a number of measures of reparation including guarantees of non-repetition and satisfaction, such as the naming of a school after the victims.

  8. The complete mitochondrial genome of the Ailanthus silkmoth, Samia cynthia cynthia (Lepidoptera: Saturniidae).

    Science.gov (United States)

    Sima, Yang-Hu; Chen, Mo; Yao, Rui; Li, Yu-Ping; Liu, Teng; Jin, Xin; Wang, Li-peng; Su, Jun-Fang; Li, Xi-Sheng; Liu, Yan-Qun

    2013-09-10

    The complete mitochondrial genome (mitogenome) of the Ailanthus silkmoth, Samia cynthia cynthia (Lepidoptera: Saturniidae) was determined. The circular genome is 15,345 bp long, and presents a typical gene organization and order for sequenced mitogenomes of Bombycidea species. The nucleotide composition of the genome is highly A+T biased, accounting for 79.86%. The AT skew of the genome is slightly negative, indicating the occurrence of more Ts than As, as found in other Saturniidae species. All protein-coding genes (PCGs) are initiated by ATN codons, except for COI and COII, which are tentatively designated by CGA and GTG, respectively, as observed in other insects. Four of 13 PCGs, including COI, COII, ATP6, and ND3, harbor the incomplete termination codons, T or TA. With an exception for tRNASer(AGN), all other tRNAs can form a typical clover-leaf structure of mitochondrial tRNA. The 359 bp A+T-rich region of S. c. cynthia contains non-repetitive sequences, but harbors several features common to the Bombycidea insects, including the motif ATAGA followed by a poly-T stretch of 19 bp, a microsatellite-like (AT)7 element preceded by the ATTTA motif, and a poly-A element upstream tRNAMet. The phylogenetic analyses support the morphology-based current hypothesis that Bombycidae and Saturniidae are monophyletic. Our result confirms that Saturniini and Attacini form a reciprocal monophyletic group within Saturniidae. Copyright © 2013 Elsevier B.V. All rights reserved.

  9. Genomic selective constraints in murid noncoding DNA.

    Directory of Open Access Journals (Sweden)

    Daniel J Gaffney

    2006-11-01

    Full Text Available Recent work has suggested that there are many more selectively constrained, functional noncoding than coding sites in mammalian genomes. However, little is known about how selective constraint varies amongst different classes of noncoding DNA. We estimated the magnitude of selective constraint on a large dataset of mouse-rat gene orthologs and their surrounding noncoding DNA. Our analysis indicates that there are more than three times as many selectively constrained, nonrepetitive sites within noncoding DNA as in coding DNA in murids. The majority of these constrained noncoding sites appear to be located within intergenic regions, at distances greater than 5 kilobases from known genes. Our study also shows that in murids, intron length and mean intronic selective constraint are negatively correlated with intron ordinal number. Our results therefore suggest that functional intronic sites tend to accumulate toward the 5' end of murid genes. Our analysis also reveals that mean number of selectively constrained noncoding sites varies substantially with the function of the adjacent gene. We find that, among others, developmental and neuronal genes are associated with the greatest numbers of putatively functional noncoding sites compared with genes involved in electron transport and a variety of metabolic processes. Combining our estimates of the total number of constrained coding and noncoding bases we calculate that over twice as many deleterious mutations have occurred in intergenic regions as in known genic sequence and that the total genomic deleterious point mutation rate is 0.91 per diploid genome, per generation. This estimated rate is over twice as large as a previous estimate in murids.

  10. Genome and phylogenetic analyses of Trypanosoma evansi reveal extensive similarity to T. brucei and multiple independent origins for dyskinetoplasty.

    Science.gov (United States)

    Carnes, Jason; Anupama, Atashi; Balmer, Oliver; Jackson, Andrew; Lewis, Michael; Brown, Rob; Cestari, Igor; Desquesnes, Marc; Gendrin, Claire; Hertz-Fowler, Christiane; Imamura, Hideo; Ivens, Alasdair; Kořený, Luděk; Lai, De-Hua; MacLeod, Annette; McDermott, Suzanne M; Merritt, Chris; Monnerat, Severine; Moon, Wonjong; Myler, Peter; Phan, Isabelle; Ramasamy, Gowthaman; Sivam, Dhileep; Lun, Zhao-Rong; Lukeš, Julius; Stuart, Ken; Schnaufer, Achim

    2015-01-01

    Two key biological features distinguish Trypanosoma evansi from the T. brucei group: independence from the tsetse fly as obligatory vector, and independence from the need for functional mitochondrial DNA (kinetoplast or kDNA). In an effort to better understand the molecular causes and consequences of these differences, we sequenced the genome of an akinetoplastic T. evansi strain from China and compared it to the T. b. brucei reference strain. The annotated T. evansi genome shows extensive similarity to the reference, with 94.9% of the predicted T. b. brucei coding sequences (CDS) having an ortholog in T. evansi, and 94.6% of the non-repetitive orthologs having a nucleotide identity of 95% or greater. Interestingly, several procyclin-associated genes (PAGs) were disrupted or not found in this T. evansi strain, suggesting a selective loss of function in the absence of the insect life-cycle stage. Surprisingly, orthologous sequences were found in T. evansi for all 978 nuclear CDS predicted to represent the mitochondrial proteome in T. brucei, although a small number of these may have lost functionality. Consistent with previous results, the F1FO-ATP synthase γ subunit was found to have an A281 deletion, which is involved in generation of a mitochondrial membrane potential in the absence of kDNA. Candidates for CDS that are absent from the reference genome were identified in supplementary de novo assemblies of T. evansi reads. Phylogenetic analyses show that the sequenced strain belongs to a dominant group of clonal T. evansi strains with worldwide distribution that also includes isolates classified as T. equiperdum. At least three other types of T. evansi or T. equiperdum have emerged independently. Overall, the elucidation of the T. evansi genome sequence reveals extensive similarity of T. brucei and supports the contention that T. evansi should be classified as a subspecies of T. brucei.

  11. Long-term monitoring of reef corals at the Flower Garden Banks (northwest Gulf of Mexico): Reef coral population changes and historical incorporation of barium in Montastrea annularis

    Energy Technology Data Exchange (ETDEWEB)

    Deslarzes, K.J.P.

    1992-01-01

    Reef coral populations were monitored from 1988 to 1991 at the Flower Garden Banks located in the northwestern Gulf of Mexico. The status of reef coral populations, and natural or man-made factors potentially affecting their well-being were determined. Man-made chronic disturbances are degrading coral reef resources on a global scale. Yet, the Flower Garden coral reefs seem to have been sheltered from the effects of regional stresses generated by population growth and increased industrial activity. Since 1974, reef coral population levels have remained unchanged in the Montastrea-Diploria Zones at the Flower Garden Banks. Live coral cover ranges between 46 and 46.5%. Montastrea annularis and Diploria strigosa comprise 80% of the coral cover on either bank. The remainder of the cover is mostly shared by eight other taxa. Coral taxa appear to be more homogeneously distributed on the West Bank. The relatively greater number of Agaricia spp., Madracis decastis, and P. astreoides colonies on the East Bank may be the source of a decreased evenness. The health of reef corals was assessed using repetitive and non-repetitive photographic methods, and accretionary growth measurements of M. annularis. Reef corals have undergone small scale changes at the Flower Gardens probably reflecting natural disturbance, predation, disease, and inter-specific competition. White mat disease (ridge disease) is shown to generate more tissue loss than any of the three bleaching events that took place at the Flower Gardens (1989, 1990, and 1991). Advance to retreat linear ratios of encrusting growth revealed a net tissue gain on the East Bank and a net tissue loss on the West Bank. Growth rates of M. annularis were highly variable. The annual barium content from 1910 in 1989 in a M. annularis colony from the West Flower Garden did not reveal trends associated with the extensive oil and gas exploration in the northern Gulf of Mexico.

  12. Persons with dementia missing in the community: Is it wandering or something unique?

    Directory of Open Access Journals (Sweden)

    Fernandez Rachael M

    2011-06-01

    Full Text Available Abstract Background At some point in the disease process many persons with dementia (PWD will have a missing incident and be unable to safely return to their care setting. In previous research studies, researchers have begun to question whether this phenomenon should continue to be called wandering since the antecedents and characteristics of a missing incident are dissimilar to accepted definitions of wandering in dementia. The purpose of this study was to confirm previous findings regarding the antecedents and characteristics of missing incidents, understand the differences between those found dead and alive, and compare the characteristics of a missing incident to that of wandering. Methods A retrospective design was used to analyse 325 newspaper reports of PWD missing in the community. Results The primary antecedent to a missing incident, particularly in community-dwelling PWD, was becoming lost while conducting a normal and permitted activity alone in the community. The other common antecedent was a lapse in supervision with the expectation that the PWD would remain in a safe location but did not. Deaths most commonly occurred in unpopulated areas due to exposure and drowning. Those who died were found closer to the place last seen and took longer to find, but there were no significant differences in gender or age. The key characteristics of a missing incident were: unpredictable, non-repetitive, temporally appropriate but spatially-disordered, and while using multiple means of movement (walking, car, public transportation. Missing incidents occurred without the discernible pattern present in wandering such as lapping or pacing, repetitive and temporally-disordered. Conclusions This research supports the mounting evidence that the concept of wandering, in its formal sense, and missing incidents are two distinct concepts. It will be important to further develop the concept of missing incidents by identifying the differences and similarities

  13. Gelotophobia and the Challenges of Implementing Laughter into Virtual Agents Interactions

    Science.gov (United States)

    Ruch, Willibald F.; Platt, Tracey; Hofmann, Jennifer; Niewiadomski, Radosław; Urbain, Jérôme; Mancini, Maurizio; Dupont, Stéphane

    2014-01-01

    This study investigated which features of AVATAR laughter are perceived threatening for individuals with a fear of being laughed at (gelotophobia), and individuals with no gelotophobia. Laughter samples were systematically varied (e.g., intensity, laughter pitch, and energy for the voice, intensity of facial actions of the face) in three modalities: animated facial expressions, synthesized auditory laughter vocalizations, and motion capture generated puppets displaying laughter body movements. In the online study 123 adults completed, the GELOPH (Ruch and Proyer, 2008a,b) and rated randomly presented videos of the three modalities for how malicious, how friendly, how real the laughter was (0 not at all to 8 extremely). Additionally, an open question asked which markers led to the perception of friendliness/maliciousness. The current study identified features in all modalities of laughter stimuli that were perceived as malicious in general, and some that were gelotophobia specific. For facial expressions of AVATARS, medium intensity laughs triggered highest maliciousness in the gelotophobes. In the auditory stimuli, the fundamental frequency modulations and the variation in intensity were indicative of maliciousness. In the body, backwards and forward movements and rocking vs. jerking movements distinguished the most malicious from the least malicious laugh. From the open answers, the shape and appearance of the lips curling induced feelings that the expression was malicious for non-gelotophobes and that the movement round the eyes, elicited the face to appear as friendly. This was opposite for gelotophobes. Gelotophobia savvy AVATARS should be of high intensity, containing lip and eye movements and be fast, non-repetitive voiced vocalization, variable and of short duration. It should not contain any features that indicate a down-regulation in the voice or body, or indicate voluntary/cognitive modulation. PMID:25477803

  14. Sensitivity pattern of Gram negative bacteria to the new β-lactam/ β-lactamase inhibitor combination: Cefepime/tazobactam

    Directory of Open Access Journals (Sweden)

    Abdul Ghafur

    2012-03-01

    Full Text Available Objectives: Increasing prevalence of carbapenem-resistant Gram negative bacteria has prompted researchers to explorealternative antibiotic options. Different ß-lactam/ß-lactamase inhibitor (BL/BLI combinations are used in manycountries, as a carbapenem saving strategy. The purpose of our study was to evaluate the sensitivity pattern of cefepime/tazobactam combination in comparison to piperacillin/tazobactam, cefoperazone/sulbactam, cefepime andcarbapenem agents.Materials and methods: We conducted retrospective analysis of the sensitivity pattern of Gram negative bacterialisolates in Apollo Speciality Hospital; a 300 bedded, tertiary care Oncology, Neurosurgical and Orthopaedic Centre inSouth India.Results: Out of the 1003 Gram negative, non-repetitive isolates collected over a period of one year; 60.5% were sensitiveto piperacillin-tazobactam, 46.2% to cefepime, 80.4% to cefepime/tazobactam, 71.3% to cefoperazone-sulbactam,79.1% to imipenem and 78.2% to meropenem. Addition of tazobactam increased the susceptibility of cefepime from46.2% to 80.4% in gram negative isolates in general; from 34.4 to 87.9% in E. coli, from 42.3 to 81.0% to Klebsiella, from72.0 to 81.4% in Pseudomonas and 17.2-54.5% to Acinetobacter.Conclusion: Cefepime/tazobactam provided a better invitro sensitivity profile than other BL-BLI combinations studied.This in vitro data needs to be confirmed by clinical studies. J Microbiol Infect Dis 2012; 2(1: 5-8

  15. Effect of combustion catalyst on the operation efficiency of steam boilers

    Science.gov (United States)

    Kapustyanskii, A. A.

    2014-09-01

    The state of the energy market of the Ukraine is analyzed. The priority of using local, low-grade solid fuel according to its flame combustion in power boilers of thermal power plants and heat and power plants in the short-term perspective is proven. Data of expert tests of boilers of TPP-210A, BKZ-160-100, BKZ-210-140, Ep-670-140, and TGM-84 models with the investigation of the effect of the addition of combustion catalyst into primary air duct on their operation efficiency are represented. Positive results are attained by burning the anthracite culm or its mixture with lean coal in all range of operating loads of boilers investigated. The possibility to eliminate the consumption of "backlighting" high-reactive fuel (natural gas or fuel oil) and to operate at steam loads below the technical minimum in the case of burning nonproject coal is given. Problems of the normalization of liquid slag run-out without closing the boiler taphole are solved.

  16. Tsunami generated by a granular collapse down a rough inclined plane

    CERN Document Server

    Viroulet, Sylvain; Kimmoun, Olivier

    2014-01-01

    In this Letter, we experimentally investigate the collapse of initially dry granular media into water and the subsequent impulse waves. We systematically characterize the influence of the slope angle and the granular material on the initial amplitude of the generated leading wave and the evolution of its amplitude during the propagation. The experiments show that whereas the evolution of the leading wave during the propagation is well predicted by a solution of the linearized Korteweg-de Vries equation, the generation of the wave is more complicated to describe. Our results suggest that the internal properties of the granular media and the interplay with the surrounding fluid are important parameters for the generation of waves at low velocity impacts. Moreover, the amplitude of the leading wave reaches a maximum value at large slope angle. The runout distance of the collapse is also shown to be smaller in the presence of water than under totally dry conditions. This study provides a first insight into tsunam...

  17. Capturing of the internal mechanics of liquid-granular flows comprised of polydisperse spherical particles

    Science.gov (United States)

    Gollin, Devis; Bowman, Elisabeth

    2017-06-01

    This paper presents a series of flume experiments designed to examine the motion and arrest of concentrated granular-fluid flows, with a view to understanding the role of polydispersity in debris flows. A non-intrusive technique is used to investigate the internal behaviour of small scale experimental flows. Three different particle size distributions comprised of polydisperse spherical particles and one with the finer component made of angular particles were analysed. The choice of using spherical shaped particles was made to improve the visualization of the internal mechanics without reducing overmuch the complexity involved in the study of these flows. We examined and compared the internal velocities of the flows and their depositional spreads. While the optical performance of the non-intrusive technique was improved, some of the characteristics commonly seen in these types of granular flows were not observed. Velocity profiles obtained in the body of the flows were similar in shape but with differences in velocity magnitude depending on the amount of fines and the angularity of the particle in one case. Depositional runouts between flows were similar at low inclinations when little internal energy was supplemented to the system or when the viscous effects dominated the mechanics at steeper angles.

  18. Slow-moving and far-travelled dense pyroclastic flows during the Peach Spring super-eruption

    Science.gov (United States)

    Roche, Olivier; Buesch, David C.; Valentine, Greg A.

    2016-01-01

    Explosive volcanic super-eruptions of several hundred cubic kilometres or more generate long run-out pyroclastic density currents the dynamics of which are poorly understood and controversial. Deposits of one such event in the southwestern USA, the 18.8 Ma Peach Spring Tuff, were formed by pyroclastic flows that travelled >170 km from the eruptive centre and entrained blocks up to ~70–90 cm diameter from the substrates along the flow paths. Here we combine these data with new experimental results to show that the flow’s base had high-particle concentration and relatively modest speeds of ~5–20 m s−1, fed by an eruption discharging magma at rates up to ~107–108 m3 s−1 for a minimum of 2.5–10 h. We conclude that sustained high-eruption discharge and long-lived high-pore pressure in dense granular dispersion can be more important than large initial velocity and turbulent transport with dilute suspension in promoting long pyroclastic flow distance.

  19. Spatial and temporal patterns of debris flow deposition in the Oregon Coast Range, USA

    Science.gov (United States)

    May, Christine L.; Gresswell, Robert E.

    2004-01-01

    Patterns of debris-flow occurrence were investigated in 125 headwater basins in the Oregon Coast Range. Time since the previous debris-flows was established using dendrochronology, and recurrence interval estimates ranged from 98 to 357 years. Tributary basins with larger drainage areas had a greater abundance of potential landslide source areas and a greater frequency of scouring events compared to smaller basins. The flux rate of material delivered to the confluence with a larger river influenced the development of small-scale debris-flow fans. Fans at the mouths of tributary basins with smaller drainage areas had a higher likelihood of being eroded by the mainstem river in the interval between debris-flows, compared to bigger basins that had larger, more persistent fans. Valley floor width of the receiving channel also influenced fan development because it limited the space available to accommodate fan formation. Of 63 recent debris-flows, 52% delivered sediment and wood directly to the mainstem river, 30% were deposited on an existing fan before reaching the mainstem, and 18% were deposited within the confines of the tributary valley before reaching the confluence. Spatial variation in the location of past and present depositional surfaces indicated that sequential debris-flow deposits did not consistently form in the same place. Instead of being spatially deterministic, results of this study suggest that temporally variable and stochastic factors may be important for predicting the runout length of debris-flows.

  20. Hydrodynamically Lubricated Rotary Shaft Having Twist Resistant Geometry

    Science.gov (United States)

    Dietle, Lannie; Gobeli, Jeffrey D.

    1993-07-27

    A hydrodynamically lubricated squeeze packing type rotary shaft with a cross-sectional geometry suitable for pressurized lubricant retention is provided which, in the preferred embodiment, incorporates a protuberant static sealing interface that, compared to prior art, dramatically improves the exclusionary action of the dynamic sealing interface in low pressure and unpressurized applications by achieving symmetrical deformation of the seal at the static and dynamic sealing interfaces. In abrasive environments, the improved exclusionary action results in a dramatic reduction of seal and shaft wear, compared to prior art, and provides a significant increase in seal life. The invention also increases seal life by making higher levels of initial compression possible, compared to prior art, without compromising hydrodynamic lubrication; this added compression makes the seal more tolerant of compression set, abrasive wear, mechanical misalignment, dynamic runout, and manufacturing tolerances, and also makes hydrodynamic seals with smaller cross-sections more practical. In alternate embodiments, the benefits enumerated above are achieved by cooperative configurations of the seal and the gland which achieve symmetrical deformation of the seal at the static and dynamic sealing interfaces. The seal may also be configured such that predetermined radial compression deforms it to a desired operative configuration, even through symmetrical deformation is lacking.

  1. Modelling the location of shallow landslides and their effects on landscape dynamics in large watersheds: An application for Northern New Zealand

    Science.gov (United States)

    Claessens, L.; Schoorl, J. M.; Veldkamp, A.

    2007-06-01

    In this study we propose a model to assess the location of shallow landslides and their impact on landscape development within a timeframe of years to decades. Processes that need to be incorporated in the model are reviewed then followed by the proposed modelling framework. The capabilities of the model are explored through an application for a forested 17 km 2 study catchment in Northern New Zealand for which digital elevation data are available with a grid resolution of 25 × 25 m. The model predicts the spatial pattern of landslide susceptibility within the simulated catchment and subsequently applies a spatial algorithm for the redistribution of failed material by effectively changing the corresponding digital elevation data after each timestep on the basis of a scenario of triggering rainfall events, relative landslide hazard and trajectories with runout criteria for failed slope material. The resulting model will form a landslide module within the dynamic landscape evolution model LAPSUS. The model forms a spatially explicit method to address the effects of shallow landslide erosion and sedimentation because digital elevation data are adapted between timesteps and on- and off-site effects over the years can be simulated in this way. By visualization of the modelling results in a GIS environment, the shifting pattern of upslope and downslope (in) stability, triggering of new landslides and the resulting slope retreat by soil material redistribution due to former mass movements can be simulated and assessed.

  2. A novel risk assessment method for landfill slope failure: Case study application for Bhalswa Dumpsite, India.

    Science.gov (United States)

    Jahanfar, Ali; Amirmojahedi, Mohsen; Gharabaghi, Bahram; Dubey, Brajesh; McBean, Edward; Kumar, Dinesh

    2017-03-01

    Rapid population growth of major urban centres in many developing countries has created massive landfills with extraordinary heights and steep side-slopes, which are frequently surrounded by illegal low-income residential settlements developed too close to landfills. These extraordinary landfills are facing high risks of catastrophic failure with potentially large numbers of fatalities. This study presents a novel method for risk assessment of landfill slope failure, using probabilistic analysis of potential failure scenarios and associated fatalities. The conceptual framework of the method includes selecting appropriate statistical distributions for the municipal solid waste (MSW) material shear strength and rheological properties for potential failure scenario analysis. The MSW material properties for a given scenario is then used to analyse the probability of slope failure and the resulting run-out length to calculate the potential risk of fatalities. In comparison with existing methods, which are solely based on the probability of slope failure, this method provides a more accurate estimate of the risk of fatalities associated with a given landfill slope failure. The application of the new risk assessment method is demonstrated with a case study for a landfill located within a heavily populated area of New Delhi, India.

  3. Particle-size segregation in dense granular avalanches

    Science.gov (United States)

    Gray, John Mark Nicholas Timm; Gajjar, Parmesh; Kokelaar, Peter

    2015-01-01

    Particles of differing sizes are notoriously prone to segregate, which is a chronic problem in the manufacture of a wide variety of products that are used by billions of people worldwide every day. Segregation is the single most important factor in product non-uniformity, which can lead to significant handling problems as well as complete batches being discarded at huge financial loss. It is generally regarded that the most important mechanism for segregation is the combination of kinetic sieving and squeeze expulsion in shallow granular avalanches. These free-surface flows are more common than one might expect, often forming part of more complicated flows in drums, heaps and silos, where there is mass exchange with underlying regions of static or slowly moving grains. The combination of segregation and solid-fluid granular phase transitions creates incredibly complicated and beautiful patterns in the resulting deposits, but a full understanding of such effects lies beyond our capabilities at present. This paper reviews recent advances in our ability to model the basic segregation processes in a single avalanche (without mass exchange) and the subtle feedback effects that they can have on the bulk flow. This is particularly important for geophysical applications, where segregation can spontaneously self-channelize and lubricate the flow, significantly enhancing the run-out of debris-flows, pyroclastic flows, rock-falls and snow-slab avalanches.

  4. Optimization Design of Suspension System Based on ADAMS%基于ADAMS的某悬架系统优化设计

    Institute of Scientific and Technical Information of China (English)

    李胜琴; 于菲

    2012-01-01

    Based on the given parameter values, the front Macpherson suspension model was built for a certain miniature car, the ADAMS/Car software was applied in the paper. The dynamics of simulation analysis on the model was done by means of wheel run-out, and K-C simulation test was carried out on the suspension system, the beating on the front wheel alignment parameters was analyzed. Finally, the optimization design was finished by the ADAMS/Insight software module, according to the simulation results, some positions of hard point and suspension parameters were optimized. The results showed that the optimization was correct and effective , and the kinematics of the suspension system was improved.%根据给定的技术参数,应用ADAMS/Car建立了某微型车的麦弗逊前悬架虚拟样机模型,对悬架系统进行K-C仿真试验,分析了车轮跳动对前轮定位参数的影响.根据仿真试验结果,利用ADAMS/Insight模块对该悬架的部分硬点位置及悬架特性参数进行了优化.优化结果表明,所做的优化设计正确有效,改善了悬架系统的运动学特性.

  5. Mathematic modeling on flexible cooling system in hot strip mill

    Institute of Scientific and Technical Information of China (English)

    彭良贵; 刘相华; 赵宪明; 吴迪

    2014-01-01

    A novel cooling system combining ultra fast cooling rigs with laminar cooling devices was investigated. Based on the different cooling mechanisms, a serial of mathematic models were established to describe the relationship between water flow and spraying pressure and the relationship between water spraying heat flux and layout of nozzles installed on the top and bottom cooling headers. Model parameters were validated by measured data. Heat transfer models including air convection model, heat radiation model and water cooling capacity model were detailedly introduced. In addition, effects on cooling capacity by water temperature and different valve patterns were also presented. Finally, the comparison results from UFC used or not have been provided with respect to temperature evolution and mechanical properties of Q235B steel grade with thickness of 7.8 mm. Since online application of the sophisticated CTC process control system based on these models, run-out table cooling control system has been running stably and reliably to produce resource-saving, low-cost steels with smaller grain size.

  6. 碳含量对TU5JP4灰铸铁冷激凸轮轴铸造弯曲变形和气孔的影响%Effect of Carbon Content on Bending Deformation and Porosity of TU5JP4 Chilled Grey Cast Iron Camshaft

    Institute of Scientific and Technical Information of China (English)

    沈保罗; 李莉; 张昊

    2012-01-01

    本文采用生产现场的大量数据,统计分析了碳含量对TU5JP4灰铸铁冷激凸轮轴弯曲变形和气孔的影响.统计数据表明,碳含量从3.4%~3.6%提高到3.6%~3.7%之间,可以较明显地降低凸轮轴的过度弯曲变形(跳动超过1mm)和气孔缺陷.用户机械加工的统计数据表明,碳含量提高后,因皮下气孔导致的废品率下降约30%.%The production data on spot have been used for statistical analysis of effect of the carbon content on bending deformation and blowhole defect of TU5JP4 chilled cast iron camshaft. It showed that increasing carbon content of the camshaft from 3.4%~3.6% to 3.6%~3.7%, has significantly reduced the bending deformation of the camshaft (radial runout more than lmm) and porosity defect. The statistics of the user showed that as the carbon content increased, the waste rate caused due to the blowhole defect decreased by about 30%.

  7. Modeling lahar behavior and hazards

    Science.gov (United States)

    Manville, Vernon; Major, Jon J.; Fagents, Sarah A.

    2013-01-01

    Lahars are highly mobile mixtures of water and sediment of volcanic origin that are capable of traveling tens to > 100 km at speeds exceeding tens of km hr-1. Such flows are among the most serious ground-based hazards at many volcanoes because of their sudden onset, rapid advance rates, long runout distances, high energy, ability to transport large volumes of material, and tendency to flow along existing river channels where populations and infrastructure are commonly concentrated. They can grow in volume and peak discharge through erosion and incorporation of external sediment and/or water, inundate broad areas, and leave deposits many meters thick. Furthermore, lahars can recur for many years to decades after an initial volcanic eruption, as fresh pyroclastic material is eroded and redeposited during rainfall events, resulting in a spatially and temporally evolving hazard. Improving understanding of the behavior of these complex, gravitationally driven, multi-phase flows is key to mitigating the threat to communities at lahar-prone volcanoes. However, their complexity and evolving nature pose significant challenges to developing the models of flow behavior required for delineating their hazards and hazard zones.

  8. Multiphase Explosions on Mars: Numerical Studies of Phreatomagmatic Blast Dynamics (Invited)

    Science.gov (United States)

    Dufek, J.

    2010-12-01

    Phreatomagmatic activity may have helped shape the surface of early Mars and the landforms generated in such events provides clues to both the magmatic and environmental conditions in the near surface. We study the dynamics of explosions generated by rapid steam generation in the near surface when magma intersects a source of liquid water or ice. Using an EEL multiphase model we study the thermal evolution in the source region, the pressure evolution due to phase change, and the compressible multiphase dynamics of the blast and subsequent gravity currents. This numerical model was validated on similar blast conditions through a sequence of scaled analogue experiments. Both the dilute and dense part of the granular flow are modeled and we correlate dynamics during the blast to eventual depositional features such as grain size sorting, flow runout, crater size and shape, and distribution of large clasts. In this way we correlate the pre-eruptive conditions to landform morphology that may be useful in interpreting on-going observations. We also report on the mixing of gas species in explosive events to better understand the distribution of water during and after the blast. Using microsphysical models we also assess the spatial and temporal potential for electrostatic and hydrous particle aggregation.

  9. Bayesian inference and model comparison for metallic fatigue data

    KAUST Repository

    Babuska, Ivo

    2016-01-06

    In this work, we present a statistical treatment of stress-life (S-N) data drawn from a collection of records of fatigue experiments that were performed on 75S-T6 aluminum alloys. Our main objective is to predict the fatigue life of materials by providing a systematic approach to model calibration, model selection and model ranking with reference to S-N data. To this purpose, we consider fatigue-limit models and random fatigue-limit models that are specially designed to allow the treatment of the run-outs (right-censored data). We first fit the models to the data by maximum likelihood methods and estimate the quantiles of the life distribution of the alloy specimen. We then compare and rank the models by classical measures of fit based on information criteria. We also consider a Bayesian approach that provides, under the prior distribution of the model parameters selected by the user, their simulation-based posterior distributions.

  10. Snow Avalanche Disturbance Ecology: Examples From the San Juan Mountains, Colorado.

    Science.gov (United States)

    Simonson, S.; Fassnacht, S. R.

    2008-12-01

    We evaluated landscape ecology approaches to characterize snow avalanche paths based on patterns of plant species composition and evidence of disturbance. Historical records of avalanche incidents, patterns in the annual growth layers of woody plants, and distributions of plant species can be used to quantify and map the frequency and magnitude of snow slide events. Near Silverton, Colorado, a series of snow storms in January of 2005 resulted in many avalanche paths running full track at 30 and 100 year return frequency. Many avalanches cut fresh trimlines, widening their tracks by uprooting, stripping, and breaking mature trees. Powerful avalanches deposited massive piles of snow, rocks, and woody debris in their runout zones. We used cross-section discs and cores of representative downed trees to detect dendro-ecological signals of past snow avalanche disturbance. Avalanche signals included impact scars from the moving snow and associated wind blast, relative width of annual growth rings, and development of reaction wood in response to tilting. Initial measurements of plant diversity and disturbance along the elevation gradient of an avalanche path near Silverton indicate that avalanche activity influences patterns of forest cover, contributes to the high local plant species diversity, and provides opportunities for new seedling establishment.

  11. The extreme mobility of debris avalanches: A new model of transport mechanism

    Science.gov (United States)

    Perinotto, Hélène; Schneider, Jean-Luc; Bachèlery, Patrick; Le Bourdonnec, François-Xavier; Famin, Vincent; Michon, Laurent

    2015-12-01

    Large rockslide-debris avalanches, resulting from flank collapses that shape volcanoes and mountains on Earth and other object of the solar system, are rapid and dangerous gravity-driven granular flows that travel abnormal distances. During the last 50 years, numerous physical models have been put forward to explain their extreme mobility. The principal models are based on fluidization, lubrication, or dynamic disintegration. However, these processes remain poorly constrained. To identify precisely the transport mechanisms during debris avalanches, we examined morphometric (fractal dimension and circularity), grain size, and exoscopic characteristics of the various types of particles (clasts and matrix) from volcanic debris avalanche deposits of La Réunion Island (Indian Ocean). From these data we demonstrate for the first time that syn-transport dynamic disintegration continuously operates with the increasing runout distance from the source down to a grinding limit of 500 µm. Below this limit, the particle size reduction exclusively results from their attrition by frictional interactions. Consequently, the exceptional mobility of debris avalanches may be explained by the combined effect of elastic energy release during the dynamic disintegration of the larger clasts and frictional reduction within the matrix due to interactions between the finer particles.

  12. A methodology for physically based rockfall hazard assessment

    Directory of Open Access Journals (Sweden)

    G. B. Crosta

    2003-01-01

    Full Text Available Rockfall hazard assessment is not simple to achieve in practice and sound, physically based assessment methodologies are still missing. The mobility of rockfalls implies a more difficult hazard definition with respect to other slope instabilities with minimal runout. Rockfall hazard assessment involves complex definitions for "occurrence probability" and "intensity". This paper is an attempt to evaluate rockfall hazard using the results of 3-D numerical modelling on a topography described by a DEM. Maps portraying the maximum frequency of passages, velocity and height of blocks at each model cell, are easily combined in a GIS in order to produce physically based rockfall hazard maps. Different methods are suggested and discussed for rockfall hazard mapping at a regional and local scale both along linear features or within exposed areas. An objective approach based on three-dimensional matrixes providing both a positional "Rockfall Hazard Index" and a "Rockfall Hazard Vector" is presented. The opportunity of combining different parameters in the 3-D matrixes has been evaluated to better express the relative increase in hazard. Furthermore, the sensitivity of the hazard index with respect to the included variables and their combinations is preliminarily discussed in order to constrain as objective as possible assessment criteria.

  13. Bayesian inference and model comparison for metallic fatigue data

    KAUST Repository

    Babuška, Ivo

    2016-02-23

    In this work, we present a statistical treatment of stress-life (S-N) data drawn from a collection of records of fatigue experiments that were performed on 75S-T6 aluminum alloys. Our main objective is to predict the fatigue life of materials by providing a systematic approach to model calibration, model selection and model ranking with reference to S-N data. To this purpose, we consider fatigue-limit models and random fatigue-limit models that are specially designed to allow the treatment of the run-outs (right-censored data). We first fit the models to the data by maximum likelihood methods and estimate the quantiles of the life distribution of the alloy specimen. To assess the robustness of the estimation of the quantile functions, we obtain bootstrap confidence bands by stratified resampling with respect to the cycle ratio. We then compare and rank the models by classical measures of fit based on information criteria. We also consider a Bayesian approach that provides, under the prior distribution of the model parameters selected by the user, their simulation-based posterior distributions. We implement and apply Bayesian model comparison methods, such as Bayes factor ranking and predictive information criteria based on cross-validation techniques under various a priori scenarios.

  14. Hydroplaning of subaqueous debris flows and glide blocks: Analytical solutions and discussion

    Science.gov (United States)

    Harbitz, Carl B.; Parker, Gary; ElverhøI, Anders; Marr, Jeffrey G.; Mohrig, David; Harff, Peter A.

    2003-07-01

    Subaqueous debris flows often attain significantly higher velocities and longer run-out distances than their subaerial counterparts in spite of increased viscous drag and reduced effective gravity due to buoyancy. Recent experimental research suggests that a basal lubricating layer of water associated with hydroplaning decouples the sediments from the bed, resulting in a dramatic reduction of the basal shear stress. Hydroplaning thus provides an explanation for these observations. The conditions for onset of hydroplaning are discussed in terms of critical densimetric Froude number. The stress reduction due to a lubricating layer of water or mud slurry is studied via equilibrium solutions for a two-layer Couette flow. The calculations reveal that the stresses in both the low-viscosity lubricating layer and the high-viscosity deforming deposits below it are substantially reduced. The principles of laminar boundary layers are used to develop an equilibrium solution for the steady motion of a hydroplaning debris glide block. This adjusted version of lubrication theory properly accounts for hydroplaning associated with a dynamic pressure generated at the head of the block. Example calculations at both laboratory and field scale support the experimental results of reduced bed friction, limited erosion, sediment rheology independence, and high velocities. The results also reveal the possibility for a net up-slope discharge in the lubricating layer.

  15. A GIS-based volcanic hazard and risk assessment of eruptions sourced within Valles Caldera, New Mexico

    Science.gov (United States)

    Alcorn, Rebecca; Panter, Kurt S.; Gorsevski, Pece V.

    2013-11-01

    The objective of this study is to evaluate the spatial extent of a possible future eruption using a GIS-based volcanic hazard tool designed to simulate pyroclastic fallout and density currents (PDCs) as well as lava flows and to assess the social and economic vulnerabilities of the area at risk. Simulated pyroclastic fallout deposits originating from the El Cajete crater within the Valles Caldera, Jemez Mountains volcanic field, New Mexico, are calibrated to isopach and lithic isopleth maps of the Lower and Upper El Cajete as constructed by Wolff et al. (2011). The change in the axial orientation of fallout deposits between the Lower and Upper El Cajete is best matched using seasonal variations in wind speed and direction based on modern atmospheric records. The calibration of PDCs is based on the distribution and run-out of the Battleship Rock Ignimbrite. Once calibrated, hazards are simulated at a second vent location determined from probability distributions of structural features. The resulting hazard simulation maps show the potential distribution of pyroclastic fallout, PDCs and lava flows, indicating areas to the S/SE of Valles Caldera to be at greatest risk.

  16. An Uncertainty Method for Probabilistic Analysis of Buildings Impacted by Rockfall in a Limestone Quarry in Fengshan, Southwestern China

    Science.gov (United States)

    Chai, Bo; Tang, Zhaohui; Zhang, Ao; Du, Juan; Su, Hongrui; Yi, Hongqing

    2015-09-01

    Rockfall is a common occurrence in open-pit mines in China, and seriously threatens lives and buildings. The damage to buildings includes many uncertainty factors, such as the occurrence of rockfall, runout trajectory, and impact energy. A uncertainty method was used to assess the probability of rockfall impacting buildings. The process includes four steps: (A) Calculating the probability of rockfall occurrence. (B) Probability analysis of the rockfall reaching the building and its energy. (C) Calculation of the building's vulnerability to rockfall impact. (D) Probability assessment of the building collapse. (E) Design options for protecting the building from rockfall damage. The method is applied in an abandoned limestone quarry in Fengshan, southwestern China. The results indicate that rockfalls have two kinds of failure modes: slide and topple, whose failure probability is 0-0.488 in the different quarry zones. The probabilities of three buildings located at the bottom of the quarry of collapsing from rockfall impact are 0.188, 0.006, and 0.002. A rockfall platform and vegetation planting at the bottom of the quarry could prevent rockfall from reaching the buildings.

  17. Corrosion behavior of chromium-free dacromet coating in seawater

    Energy Technology Data Exchange (ETDEWEB)

    Hu Huili [Department of Chemistry of Harbin Institute of Technology, Harbin 150001 (China); Department of Ocean of Harbin Institute of Technology at WeiHai, WeiHai 264209 (China); Li Ning [Department of Chemistry of Harbin Institute of Technology, Harbin 150001 (China) and Department of Ocean of Harbin Institute of Technology at WeiHai, WeiHai 264209 (China)], E-mail: lininghit@126.com; Cheng Jinning; Chen Lijiao [Department of Ocean of Harbin Institute of Technology at WeiHai, WeiHai 264209 (China)

    2009-03-20

    In order to overcome the environmental objection of chromium(VI) in dacromet, a novel chromium-free dacromet was developed. Electrochemical impedance spectroscopy (EIS) and d.c. potential measurements were employed to study the anticorrosion behavior of the sintered ceramic zinc-aluminum coatings in still seawater. Results of X-ray diffraction (XRD) indicate that the main corrosion products are composed of Al{sub 2}O{sub 3}, ZnCl{sub 2}, Zn(OH){sub 2} and Fe{sub 2}O{sub 3}. The scanning electron microscope (SEM) and energy dispersive X-ray spectroscope (EDX) analysis were carried out to study the morphological appearance and the local chemical composition of run-out coatings. The results show that the evolution of open circuit potential can be divided into four stages during the lifetime of CFD/steel. The EIS behaviors of Zn-Al coatings immersion in seawater at the first day are similar to the ceramic CrN coating prepared by PVD, while the impedance data of the next days are parallel with multilayer protective coatings. The galvanic protection effect of the coating keeps active only in the first 3 days and then the physical shielding function play a dominant role.

  18. Seismology of the Oso-Steelhead landslide

    Directory of Open Access Journals (Sweden)

    C. Hibert

    2014-12-01

    Full Text Available We carry out a combined analysis of the short- and long-period seismic signals generated by the devastating Oso-Steelhead landslide that occurred on 22 March 2014. The seismic records show that the Oso-Steelhead landslide was not a single slope failure, but a succession of multiple failures distinguished by two major collapses that occurred approximately three minutes apart. The first generated long-period surface waves that were recorded at several proximal stations. We invert these long-period signals for the forces acting at the source, and obtain estimates of the first failure runout and kinematics, as well as its mass after calibration against the mass-center displacement estimated from remote-sensing imagery. Short-period analysis of both events suggests that the source dynamics of the second are more complex than the first. No distinct long-period surface waves were recorded for the second failure, which prevents inversion for its source parameters. However, by comparing the seismic energy of the short-period waves generated by both events we are able to estimate the volume of the second. Our analysis suggests that the volume of the second failure is about 15–30% of the total landslide volume, which is in agreement with ground observations.

  19. Thermal and destructive interrogation of ceramic matrix composites

    Science.gov (United States)

    Ojard, Greg; Doza, Douglas; Ouyang, Zhong; Angel, Paul; Smyth, Imelda; Santhosh, Unni; Ahmad, Jalees; Gowayed, Yasser

    2015-03-01

    Ceramic matrix composites are intended for elevated temperature use and their performance at temperature must be clearly understood as insertion efforts are to be realized. Most efforts to understand ceramic matrix composites at temperature are based on their lifetime at temperature under stress based on fatigue or creep testing or residual testing after some combination of temperature, stress and time. While these efforts can be insightful especially based on their mechanical performance, there is no insight into how other properties are changing with thermal exposure. To gain additional insight into oxidation behavior of CMC samples, a series of fatigue and creep samples tested at two different temperatures were non-destructively interrogated after achieving run-out conditions by multiple thermal methods and limited X-ray CT. After non-destructive analysis, residual tensile tests were undertaken at room temperature. The resulting residual properties will be compared against the non-destructive data. Analysis will be done to see if data trends can be determined and correlated to the level and duration of exposure.

  20. A unified framework for modeling landscape evolution by discrete flows

    Science.gov (United States)

    Shelef, Eitan; Hilley, George E.

    2016-05-01

    Topographic features such as branched valley networks and undissected convex-up hillslopes are observed in disparate physical environments. In some cases, these features are formed by sediment transport processes that occur discretely in space and time, while in others, by transport processes that are uniformly distributed across the landscape. This paper presents an analytical framework that reconciles the basic attributes of such sediment transport processes with the topographic features that they form and casts those in terms that are likely common to different physical environments. In this framework, temporal changes in surface elevation reflect the frequency with which the landscape is traversed by geophysical flows generated discretely in time and space. This frequency depends on the distance to which flows travel downslope, which depends on the dynamics of individual flows, the lithologic and topographic properties of the underlying substrate, and the coevolution of topography, erosion, and the routing of flows over the topographic surface. To explore this framework, we postulate simple formulations for sediment transport and flow runout distance and demonstrate that the conditions for hillslope and channel network formation can be cast in terms of fundamental parameters such as distance from drainage divide and a friction-like coefficient that describes a flow's resistance to motion. The framework we propose is intentionally general, but the postulated formulas can be substituted with those that aim to describe a specific process and to capture variations in the size distribution of such flow events.

  1. Utilization of advanced calibration techniques in stochastic rock fall analysis of quarry slopes

    Science.gov (United States)

    Preh, Alexander; Ahmadabadi, Morteza; Kolenprat, Bernd

    2016-04-01

    In order to study rock fall dynamics, a research project was conducted by the Vienna University of Technology and the Austrian Central Labour Inspectorate (Federal Ministry of Labour, Social Affairs and Consumer Protection). A part of this project included 277 full-scale drop tests at three different quarries in Austria and recording key parameters of the rock fall trajectories. The tests involved a total of 277 boulders ranging from 0.18 to 1.8 m in diameter and from 0.009 to 8.1 Mg in mass. The geology of these sites included strong rock belonging to igneous, metamorphic and volcanic types. In this paper the results of the tests are used for calibration and validation a new stochastic computer model. It is demonstrated that the error of the model (i.e. the difference between observed and simulated results) has a lognormal distribution. Selecting two parameters, advanced calibration techniques including Markov Chain Monte