WorldWideScience

Sample records for nonlinear processes involved

  1. A non-linear decision making process for public involvement in environmental management activities

    International Nuclear Information System (INIS)

    Harper, M.R.; Kastenberg, W.

    1995-01-01

    The international industrial and governmental institutions involved in radioactive waste management and environmental remediation are now entering a new era in which they must significantly expand public involvement. Thus the decision making processes formerly utilized to direct and guide these institutions must now be shifted to take into consideration the needs of many more stakeholders than ever before. To meet this challenge, they now have the job of developing and creating a new set of accurate, sufficient and continuous self-regulating and self-correcting information pathways between themselves and the many divergent stakeholder groups in order to establish sustainable, trusting and respectful relationships. In this paper the authors introduce a new set of non-linear, practical and effective strategies for interaction. These self-regulating strategies provide timely feedback to a system, establishing trust and creating a viable vehicle for staying open and responsive to the needs out of which change and balanced adaptation can continually emerge for all stakeholders. The authors present a decision making process for public involvement which is congruent with the non-linear ideas of holographic and fractal relationships -- the mutual influence between related parts of the whole and the self-symmetry of systems at every level of complexity

  2. Nonlinear filtering for LIDAR signal processing

    Directory of Open Access Journals (Sweden)

    D. G. Lainiotis

    1996-01-01

    Full Text Available LIDAR (Laser Integrated Radar is an engineering problem of great practical importance in environmental monitoring sciences. Signal processing for LIDAR applications involves highly nonlinear models and consequently nonlinear filtering. Optimal nonlinear filters, however, are practically unrealizable. In this paper, the Lainiotis's multi-model partitioning methodology and the related approximate but effective nonlinear filtering algorithms are reviewed and applied to LIDAR signal processing. Extensive simulation and performance evaluation of the multi-model partitioning approach and its application to LIDAR signal processing shows that the nonlinear partitioning methods are very effective and significantly superior to the nonlinear extended Kalman filter (EKF, which has been the standard nonlinear filter in past engineering applications.

  3. Modeling of nonlinear responses for reciprocal transducers involving polarization switching

    DEFF Research Database (Denmark)

    Willatzen, Morten; Wang, Linxiang

    2007-01-01

    Nonlinearities and hysteresis effects in a reciprocal PZT transducer are examined by use of a dynamical mathematical model on the basis of phase-transition theory. In particular, we consider the perovskite piezoelectric ceramic in which the polarization process in the material can be modeled...... by Landau theory for the first-order phase transformation, in which each polarization state is associated with a minimum of the Landau free-energy function. Nonlinear constitutive laws are obtained by using thermodynamical equilibrium conditions, and hysteretic behavior of the material can be modeled...... intrinsically. The time-dependent Ginzburg-Landau theory is used in the parameter identification involving hysteresis effects. We use the Chebyshev collocation method in the numerical simulations. The elastic field is assumed to be coupled linearly with other fields, and the nonlinearity is in the E-D coupling...

  4. Nonlinear Markov processes: Deterministic case

    International Nuclear Information System (INIS)

    Frank, T.D.

    2008-01-01

    Deterministic Markov processes that exhibit nonlinear transition mechanisms for probability densities are studied. In this context, the following issues are addressed: Markov property, conditional probability densities, propagation of probability densities, multistability in terms of multiple stationary distributions, stability analysis of stationary distributions, and basin of attraction of stationary distribution

  5. Nonlinear Process Fault Diagnosis Based on Serial Principal Component Analysis.

    Science.gov (United States)

    Deng, Xiaogang; Tian, Xuemin; Chen, Sheng; Harris, Chris J

    2018-03-01

    Many industrial processes contain both linear and nonlinear parts, and kernel principal component analysis (KPCA), widely used in nonlinear process monitoring, may not offer the most effective means for dealing with these nonlinear processes. This paper proposes a new hybrid linear-nonlinear statistical modeling approach for nonlinear process monitoring by closely integrating linear principal component analysis (PCA) and nonlinear KPCA using a serial model structure, which we refer to as serial PCA (SPCA). Specifically, PCA is first applied to extract PCs as linear features, and to decompose the data into the PC subspace and residual subspace (RS). Then, KPCA is performed in the RS to extract the nonlinear PCs as nonlinear features. Two monitoring statistics are constructed for fault detection, based on both the linear and nonlinear features extracted by the proposed SPCA. To effectively perform fault identification after a fault is detected, an SPCA similarity factor method is built for fault recognition, which fuses both the linear and nonlinear features. Unlike PCA and KPCA, the proposed method takes into account both linear and nonlinear PCs simultaneously, and therefore, it can better exploit the underlying process's structure to enhance fault diagnosis performance. Two case studies involving a simulated nonlinear process and the benchmark Tennessee Eastman process demonstrate that the proposed SPCA approach is more effective than the existing state-of-the-art approach based on KPCA alone, in terms of nonlinear process fault detection and identification.

  6. Multiorder nonlinear diffraction in frequency doubling processes

    DEFF Research Database (Denmark)

    Saltiel, Solomon M.; Neshev, Dragomir N.; Krolikowski, Wieslaw

    2009-01-01

    We analyze experimentally light scattering from 2 nonlinear gratings and observe two types of second-harmonic frequency-scattering processes. The first process is identified as Raman–Nath type nonlinear diffraction that is explained by applying only transverse phase-matching conditions. The angular...... position of this type of diffraction is defined by the ratio of the second-harmonic wavelength and the grating period. In contrast, the second type of nonlinear scattering process is explained by the longitudinal phase matching only, being insensitive to the nonlinear grating...

  7. Nonlinear transformations of random processes

    CERN Document Server

    Deutsch, Ralph

    2017-01-01

    This concise treatment of nonlinear noise techniques encountered in system applications is suitable for advanced undergraduates and graduate students. It is also a valuable reference for systems analysts and communication engineers. 1962 edition.

  8. Broadband Nonlinear Signal Processing in Silicon Nanowires

    DEFF Research Database (Denmark)

    Yvind, Kresten; Pu, Minhao; Hvam, Jørn Märcher

    The fast non-linearity of silicon allows Tbit/s optical signal processing. By choosing suitable dimensions of silicon nanowires their dispersion can be tailored to ensure a high nonlinearity at power levels low enough to avoid significant two-photon abso We have fabricated low insertion...

  9. Input saturation in nonlinear multivariable processes resolved by nonlinear decoupling

    Directory of Open Access Journals (Sweden)

    Jens G. Balchen

    1995-04-01

    Full Text Available A new method is presented for the resolution of the problem of input saturation in nonlinear multivariable process control by means of elementary nonlinear decoupling (END. Input saturation can have serious consequences particularly in multivariable control because it may lead to very undesirable system behaviour and quite often system instability. Many authors have searched for systematic techniques for designing multivariable control systems in which saturation may occur in any of the control variables (inputs, manipulated variables. No generally accepted method seems to have been presented so far which gives a solution in closed form. The method of elementary nonlinear decoupling (END can be applied directly to the case of saturation control variables by deriving as many control strategies as there are combinations of saturating control variables. The method is demonstrated by the multivariable control of a simulated Fluidized Catalytic Cracker (FCC with very convincing results.

  10. Image processing with a cellular nonlinear network

    International Nuclear Information System (INIS)

    Morfu, S.

    2005-01-01

    A cellular nonlinear network (CNN) based on uncoupled nonlinear oscillators is proposed for image processing purposes. It is shown theoretically and numerically that the contrast of an image loaded at the nodes of the CNN is strongly enhanced, even if this one is initially weak. An image inversion can be also obtained without reconfiguration of the network whereas a gray levels extraction can be performed with an additional threshold filtering. Lastly, an electronic implementation of this CNN is presented

  11. Nonlinear signal processing using neural networks: Prediction and system modelling

    Energy Technology Data Exchange (ETDEWEB)

    Lapedes, A.; Farber, R.

    1987-06-01

    The backpropagation learning algorithm for neural networks is developed into a formalism for nonlinear signal processing. We illustrate the method by selecting two common topics in signal processing, prediction and system modelling, and show that nonlinear applications can be handled extremely well by using neural networks. The formalism is a natural, nonlinear extension of the linear Least Mean Squares algorithm commonly used in adaptive signal processing. Simulations are presented that document the additional performance achieved by using nonlinear neural networks. First, we demonstrate that the formalism may be used to predict points in a highly chaotic time series with orders of magnitude increase in accuracy over conventional methods including the Linear Predictive Method and the Gabor-Volterra-Weiner Polynomial Method. Deterministic chaos is thought to be involved in many physical situations including the onset of turbulence in fluids, chemical reactions and plasma physics. Secondly, we demonstrate the use of the formalism in nonlinear system modelling by providing a graphic example in which it is clear that the neural network has accurately modelled the nonlinear transfer function. It is interesting to note that the formalism provides explicit, analytic, global, approximations to the nonlinear maps underlying the various time series. Furthermore, the neural net seems to be extremely parsimonious in its requirements for data points from the time series. We show that the neural net is able to perform well because it globally approximates the relevant maps by performing a kind of generalized mode decomposition of the maps. 24 refs., 13 figs.

  12. Ultrafast Nonlinear Signal Processing in Silicon Waveguides

    DEFF Research Database (Denmark)

    Oxenløwe, Leif Katsuo; Mulvad, Hans Christian Hansen; Hu, Hao

    2012-01-01

    We describe recent demonstrations of exploiting highly nonlinear silicon waveguides for ultrafast optical signal processing. We describe wavelength conversion and serial-to-parallel conversion of 640 Gbit/s data signals and 1.28 Tbit/s demultiplexing and all-optical sampling.......We describe recent demonstrations of exploiting highly nonlinear silicon waveguides for ultrafast optical signal processing. We describe wavelength conversion and serial-to-parallel conversion of 640 Gbit/s data signals and 1.28 Tbit/s demultiplexing and all-optical sampling....

  13. Quantum Information Processing using Nonlinear Optical Effects

    DEFF Research Database (Denmark)

    Andersen, Lasse Mejling

    This PhD thesis treats applications of nonlinear optical effects for quantum information processing. The two main applications are four-wave mixing in the form of Bragg scattering (BS) for quantum-state-preserving frequency conversion, and sum-frequency generation (SFG) in second-order nonlinear......-chirping the pumps. In the high-conversion regime without the effects of NPM, exact Green functions for BS are derived. In this limit, separability is possible for conversion efficiencies up to 60 %. However, the system still allows for selective frequency conversion as well as re-shaping of the output. One way...

  14. Recent advances in nonlinear speech processing

    CERN Document Server

    Faundez-Zanuy, Marcos; Esposito, Antonietta; Cordasco, Gennaro; Drugman, Thomas; Solé-Casals, Jordi; Morabito, Francesco

    2016-01-01

    This book presents recent advances in nonlinear speech processing beyond nonlinear techniques. It shows that it exploits heuristic and psychological models of human interaction in order to succeed in the implementations of socially believable VUIs and applications for human health and psychological support. The book takes into account the multifunctional role of speech and what is “outside of the box” (see Björn Schuller’s foreword). To this aim, the book is organized in 6 sections, each collecting a small number of short chapters reporting advances “inside” and “outside” themes related to nonlinear speech research. The themes emphasize theoretical and practical issues for modelling socially believable speech interfaces, ranging from efforts to capture the nature of sound changes in linguistic contexts and the timing nature of speech; labors to identify and detect speech features that help in the diagnosis of psychological and neuronal disease, attempts to improve the effectiveness and performa...

  15. DHA involvement in neurotransmission process

    Directory of Open Access Journals (Sweden)

    Vancassel Sylvie

    2007-05-01

    Full Text Available The very high enrichment of the nervous system in the polyunsaturated fatty acids, arachidonic (AA, 20: 4n-6 and docosahexaenoic acids (DHA, 22: 6n-3, is dependant of the dietary availability of their respective precursors, linoleic (18: 2n-6 and_-linolenic acids (18: 3n-3. Inadequate amounts of DHA in brain membranes have been linked to a wide variety of abnormalities ranging from visual acuity and learning irregularities, to psychopathologies. However, the molecular mechanisms involved remain unknown. Several years ago, we hypothesized that a modification of DHA contents of neuronal membranes by dietary modulation could change the neurotransmission function and then underlie inappropriate behavioural response. We showed that, in parallel to a severe loss of brain DHA concomitant to a compensatory substitution by 22:5n-6, the dietary lack of α-linolenic acid during development induced important changes in the release of neurotransmitters (dopamine, serotonin, acetylcholine in cerebral areas specifically involved in learning, memory and reward processes. Data suggested alteration of presynaptic storage process and dysregulations of reciprocal functional interactions between monoaminergic and cholinergic pathways. Moreover, we showed that recovery of these neurochemical changes was possible when the deficient diet was switched to a diet balanced in n-3 and n-6 PUFA before weaning. The next step is to understand the mechanism involved. Particularly, we focus on the study of the metabolic cooperation between the endothelial cell, the astrocyte and the neuron which regulate synaptic transmission.These works could contribute to the understanding of the link between some neuropsychiatric disorders and the metabolism of n-3 PUFA, through their action on neurotransmission.

  16. Internal Decoupling in Nonlinear Process Control

    Directory of Open Access Journals (Sweden)

    Jens G. Balchen

    1988-07-01

    Full Text Available A simple method has been investigated for the total or partial removal of the effect of non-linear process phenomena in multi-variable feedback control systems. The method is based upon computing the control variables which will drive the process at desired rates. It is shown that the effect of model errors in the linearization of the process can be partly removed through the use of large feedback gains. In practice there will be limits on how large gains can he used. The sensitivity to parameter errors is less pronounced and the transient behaviour is superior to that of ordinary PI controllers.

  17. Nonlinearly perturbed semi-Markov processes

    CERN Document Server

    Silvestrov, Dmitrii

    2017-01-01

    The book presents new methods of asymptotic analysis for nonlinearly perturbed semi-Markov processes with a finite phase space. These methods are based on special time-space screening procedures for sequential phase space reduction of semi-Markov processes combined with the systematical use of operational calculus for Laurent asymptotic expansions. Effective recurrent algorithms are composed for getting asymptotic expansions, without and with explicit upper bounds for remainders, for power moments of hitting times, stationary and conditional quasi-stationary distributions for nonlinearly perturbed semi-Markov processes. These results are illustrated by asymptotic expansions for birth-death-type semi-Markov processes, which play an important role in various applications. The book will be a useful contribution to the continuing intensive studies in the area. It is an essential reference for theoretical and applied researchers in the field of stochastic processes and their applications that will cont...

  18. Nonlinear dynamic processes in modified ionospheric plasma

    Science.gov (United States)

    Kochetov, A.; Terina, G.

    Presented work is a contribution to the experimental and theoretical study of nonlinear effects arising on ionospheric plasma under the action of powerful radio emission (G.I. Terina, J. Atm. Terr. Phys., 1995, v.57, p.273; A.V. Kochetov et. al., Advances in Space Research, 2002, in press). The experimental results were obtained by the method of sounding of artificially disturbed ionosphere by short radio pulses. The amplitude and phase characteristics of scattered signal as of "caviton" type (CS) (analogy of narrow-band component of stimulation electromagnetic emission (SEE)) as the main signal (MS) of probing transmitter are considered. The theoretical model is based on numerical solution of driven nonlinear Shrödinger equation (NSE) in inhomogeneous plasma. The simulation allows us to study a self-consistent spatial-temporal dynamics of field and plasma. The observed evolution of phase characteristics of MS and CS qualitatively correspond to the results of numerical simulation and demonstrate the penetration processes of powerful electromagnetic wave in supercritical (in linear approach) plasma regions. The modeling results explain also the periodic generation of CS, the travel CS maximum down to density gradient, the aftereffect of CS. The obtained results show the excitation of strong turbulence and allow us to interpret CS, NC and so far inexplicable phenomena as "spikes" too. The work was supported in part by Russian Foundation for Basic Research (grants Nos. 99-02-16642, 99-02- 16399).

  19. DHA involvement in neurotransmission process

    OpenAIRE

    Vancassel Sylvie; Aïd Sabah; Denis Isabelle; Guesnet Philippe; Lavialle Monique

    2007-01-01

    The very high enrichment of the nervous system in the polyunsaturated fatty acids, arachidonic (AA, 20: 4n-6) and docosahexaenoic acids (DHA, 22: 6n-3), is dependant of the dietary availability of their respective precursors, linoleic (18: 2n-6) and_-linolenic acids (18: 3n-3). Inadequate amounts of DHA in brain membranes have been linked to a wide variety of abnormalities ranging from visual acuity and learning irregularities, to psychopathologies. However, the molecular mechanisms involved ...

  20. Corrugated Membrane Nonlinear Deformation Process Calculation

    Directory of Open Access Journals (Sweden)

    A. S. Nikolaeva

    2015-01-01

    Full Text Available Elastic elements are widely used in instrumentation. They are used to create a particular interference between the parts, for accumulating mechanical energy, as the motion transmission elements, elastic supports, and sensing elements of measuring devices. Device reliability and quality depend on the calculation accuracy of the elastic elements. A corrugated membrane is rather common embodiment of the elastic element.The corrugated membrane properties depend largely on its profile i.e. a generatrix of the meridian surface.Unlike other types of pressure elastic members (bellows, tube spring, the elastic characteristics of which are close to linear, an elastic characteristic of the corrugated membrane (typical movement versus external load is nonlinear. Therefore, the corrugated membranes can be used to measure quantities, nonlinearly related to the pressure (e.g., aircraft air speed, its altitude, pipeline fluid or gas flow rate. Another feature of the corrugated membrane is that significant movements are possible within the elastic material state. However, a significant non-linearity of membrane characteristics leads to severe complicated calculation.This article is aimed at calculating the corrugated membrane to obtain the elastic characteristics and the deformed shape of the membrane meridian, as well as at investigating the processes of buckling. As the calculation model, a thin-walled axisymmetric shell rotation is assumed. The material properties are linearly elastic. We consider a corrugated membrane of sinusoidal profile. The membrane load is a uniform pressure.The algorithm for calculating the mathematical model of an axisymmetric corrugated membrane of constant thickness, based on the Reissner’s theory of elastic thin shells, was realized as the author's program in C language. To solve the nonlinear problem were used a method of changing the subspace of control parameters, developed by S.S., Gavriushin, and a parameter marching method

  1. Recombination Processes and Nonlinear Markov Chains.

    Science.gov (United States)

    Pirogov, Sergey; Rybko, Alexander; Kalinina, Anastasia; Gelfand, Mikhail

    2016-09-01

    Bacteria are known to exchange genetic information by horizontal gene transfer. Since the frequency of homologous recombination depends on the similarity between the recombining segments, several studies examined whether this could lead to the emergence of subspecies. Most of them simulated fixed-size Wright-Fisher populations, in which the genetic drift should be taken into account. Here, we use nonlinear Markov processes to describe a bacterial population evolving under mutation and recombination. We consider a population structure as a probability measure on the space of genomes. This approach implies the infinite population size limit, and thus, the genetic drift is not assumed. We prove that under these conditions, the emergence of subspecies is impossible.

  2. PLASMA EMISSION BY NONLINEAR ELECTROMAGNETIC PROCESSES

    Energy Technology Data Exchange (ETDEWEB)

    Ziebell, L. F.; Petruzzellis, L. T.; Gaelzer, R. [Instituto de Física, UFRGS, Porto Alegre, RS (Brazil); Yoon, P. H. [Institute for Physical Science and Technology, University of Maryland, College Park (United States); Pavan, J., E-mail: luiz.ziebell@ufrgs.br, E-mail: laripetruzzellis@yahoo.com.br, E-mail: rudi.gaelzer@ufrgs.br, E-mail: yoonp@umd.edu, E-mail: joel.pavan@ufpel.edu.br [Instituto de Física e Matemática, UFPel, Pelotas, RS (Brazil)

    2015-06-20

    The plasma emission, or electromagnetic (EM) radiation at the plasma frequency and/or its harmonic(s), is generally accepted as the radiation mechanism responsible for solar type II and III radio bursts. Identification and characterization of these solar radio burst phenomena were done in the 1950s. Despite many decades of theoretical research since then, a rigorous demonstration of the plasma emission process based upon first principles was not available until recently, when, in a recent Letter, Ziebell et al. reported the first complete numerical solution of EM weak turbulence equations; thus, quantitatively analyzing the plasma emission process starting from the initial electron beam and the associated beam-plasma (or Langmuir wave) instability, as well as the subsequent nonlinear conversion of electrostatic Langmuir turbulence into EM radiation. In the present paper, the same problem is revisited in order to elucidate the detailed physical mechanisms that could not be reported in the brief Letter format. Findings from the present paper may be useful for interpreting observations and full-particle numerical simulations.

  3. Optoelectronic and nonlinear optical processes in low dimensional ...

    Indian Academy of Sciences (India)

    Optoelectronic process; nonlinear optical process; semiconductor. Quest for ever faster and intelligent information processing technologies has sparked ..... Schematic energy level diagram for the proposed 4-level model. States other than the.

  4. User involvement in the innovation process

    DEFF Research Database (Denmark)

    Christensen, Dan Saugstrup

    2008-01-01

    User involvement in the innovation process is not a new phenomenon. However, combined with the growing individualisation of demand and with highly competitive and dynamic environments, user involvement in the innovation process and thereby in the design, development, and manufacturing process, can...... nevertheless provide a competitive advantage. This is the case as an intensified user involvement in the innovation process potentially results in a more comprehensive understanding of the user needs and requirements and the context within which these are required, and thereby provides the possibility...... of developing better and more suitable products. The theoretical framework of this thesis is based on user involvement in the innovation process and how user involvement in the innovation process can be deployed in relation to deriving and colleting user needs and requirements, and thereby serves...

  5. Some nonlinear processes relevant to the beat wave accelerator

    International Nuclear Information System (INIS)

    Bingham, R.; Mori, W.B.

    1985-03-01

    The beat wave accelerator depends on the generation of a large amplitude plasma wave with a phase velocity close to the velocity of light c. The plasma wave (ωsub(p), ksub(p)) is generated by beating colinear laser beams (ω 1 , k 1 ) and (ω 2 ,k 2 ) with ωsub(p) = ω 1 -ω 2 , ksub(p) = k 1 -k 2 . Since the process involves both large amplitude transverse and longitudinal waves, various nonlinear instabilities associated with either wave may occur. The object of the article is to discuss some of the processes that may compete with the beat wave generation listing their threshold and growth rate. (author)

  6. Results of nonlinear and nonstationary image processing

    International Nuclear Information System (INIS)

    Pizer, S.M.; Correla, J.A.; Chesler, D.A.; Metz, C.E.

    1973-01-01

    A nonstationary method, multiple z-divided filtering, and a nonlinear method, biased smearing have been applied to scintigrams. Biased smearing does not appear to hold much promise. Multiple z-divided filtering, on the other hand, appears to be justified, and initial results at minimum encourage further research into the possibility that this technique may become a method of choice

  7. Getting Involved in the IEP Process

    Science.gov (United States)

    Kowalski, Ellen; Lieberman, Lauren J.; Daggett, Sara

    2006-01-01

    Although, in many districts, physical educators are integral members of the Individualized Education Program (designed for students with disabilities such as Down syndrome and autism), in other districts, physical educators are only partially involved in the process or are not given the opportunity to be involved at all. However, the physical…

  8. Bubble nonlinear dynamics and stimulated scattering process

    Science.gov (United States)

    Jie, Shi; De-Sen, Yang; Sheng-Guo, Shi; Bo, Hu; Hao-Yang, Zhang; Shi-Yong, Hu

    2016-02-01

    A complete understanding of the bubble dynamics is deemed necessary in order to achieve their full potential applications in industry and medicine. For this purpose it is first needed to expand our knowledge of a single bubble behavior under different possible conditions including the frequency and pressure variations of the sound field. In addition, stimulated scattering of sound on a bubble is a special effect in sound field, and its characteristics are associated with bubble oscillation mode. A bubble in liquid can be considered as a representative example of nonlinear dynamical system theory with its resonance, and its dynamics characteristics can be described by the Keller-Miksis equation. The nonlinear dynamics of an acoustically excited gas bubble in water is investigated by using theoretical and numerical analysis methods. Our results show its strongly nonlinear behavior with respect to the pressure amplitude and excitation frequency as the control parameters, and give an intuitive insight into stimulated sound scattering on a bubble. It is seen that the stimulated sound scattering is different from common dynamical behaviors, such as bifurcation and chaos, which is the result of the nonlinear resonance of a bubble under the excitation of a high amplitude acoustic sound wave essentially. The numerical analysis results show that the threshold of stimulated sound scattering is smaller than those of bifurcation and chaos in the common condition. Project supported by the Program for Changjiang Scholars and Innovative Research Team in University, China (Grant No. IRT1228) and the Young Scientists Fund of the National Natural Science Foundation of China (Grant Nos. 11204050 and 11204049).

  9. Nonlinear radiation transport problems involving widely varying mean free paths

    International Nuclear Information System (INIS)

    Chapline, G. Jr.; Wood, L.

    1976-01-01

    In this report a method is given for modifying the Monte-Carlo approach so that one can accurately treat problems that involve both large and small mean free paths. This method purports to offer the advantages of the general Monte Carlo technique as far as relatively great accuracy of simulation of microscopic physical phenomena is concerned, and the advantage of a diffusion theory approach as far as decent time steps in thick problems are concerned; it does suffer from something of the statistical fluctuation problems of the Monte Carlo, although in analytically attenuated and modified form

  10. NONLINEAR MODEL PREDICTIVE CONTROL OF CHEMICAL PROCESSES

    Directory of Open Access Journals (Sweden)

    SILVA R. G.

    1999-01-01

    Full Text Available A new algorithm for model predictive control is presented. The algorithm utilizes a simultaneous solution and optimization strategy to solve the model's differential equations. The equations are discretized by equidistant collocation, and along with the algebraic model equations are included as constraints in a nonlinear programming (NLP problem. This algorithm is compared with the algorithm that uses orthogonal collocation on finite elements. The equidistant collocation algorithm results in simpler equations, providing a decrease in computation time for the control moves. Simulation results are presented and show a satisfactory performance of this algorithm.

  11. Spin versus helicity in processes involving transversity

    CERN Document Server

    Mekhfi, Mustapha

    2011-01-01

    We construct the spin formalism in order to deal in a direct and natural way with processes involving transversity which are now of increasing popularity. The helicity formalism which is more appropriate for collision processes of definite helicity has been so far used also to manage processes with transversity, but at the price of computing numerous helicity amplitudes generally involving unnecessary kinematical variables.In a second step we work out the correspondence between both formalisms and retrieve in another way all results of the helicity formalism but in simpler forms.We then compute certain processes for comparison.A special process:the quark dipole magnetic moment is shown to be exclusively treated within the spin formalism as it is directly related to the transverse spin of the quark inside the baryon.

  12. Involving IDPs in the Darfur peace process

    Directory of Open Access Journals (Sweden)

    David Lanz

    2008-04-01

    Full Text Available The UN estimates that there are 2.4 millionIDPs in Darfur –over one third of the totalpopulation. There can be no meaningfulpeace process without their involvement.Giving IDPs a formal seat in official peacenegotiations is problematic but there areother ways to ensure their participation.

  13. Nonlinear partial least squares with Hellinger distance for nonlinear process monitoring

    KAUST Repository

    Harrou, Fouzi

    2017-02-16

    This paper proposes an efficient data-based anomaly detection method that can be used for monitoring nonlinear processes. The proposed method merges advantages of nonlinear projection to latent structures (NLPLS) modeling and those of Hellinger distance (HD) metric to identify abnormal changes in highly correlated multivariate data. Specifically, the HD is used to quantify the dissimilarity between current NLPLS-based residual and reference probability distributions. The performances of the developed anomaly detection using NLPLS-based HD technique is illustrated using simulated plug flow reactor data.

  14. Nonlinear partial least squares with Hellinger distance for nonlinear process monitoring

    KAUST Repository

    Harrou, Fouzi; Madakyaru, Muddu; Sun, Ying

    2017-01-01

    This paper proposes an efficient data-based anomaly detection method that can be used for monitoring nonlinear processes. The proposed method merges advantages of nonlinear projection to latent structures (NLPLS) modeling and those of Hellinger distance (HD) metric to identify abnormal changes in highly correlated multivariate data. Specifically, the HD is used to quantify the dissimilarity between current NLPLS-based residual and reference probability distributions. The performances of the developed anomaly detection using NLPLS-based HD technique is illustrated using simulated plug flow reactor data.

  15. Ultra-Fast Optical Signal Processing in Nonlinear Silicon Waveguides

    DEFF Research Database (Denmark)

    Oxenløwe, Leif Katsuo; Galili, Michael; Pu, Minhao

    2011-01-01

    We describe recent demonstrations of exploiting highly nonlinear silicon nanowires for processing Tbit/s optical data signals. We perform demultiplexing and optical waveform sampling of 1.28 Tbit/s and wavelength conversion of 640 Gbit/s data signals.......We describe recent demonstrations of exploiting highly nonlinear silicon nanowires for processing Tbit/s optical data signals. We perform demultiplexing and optical waveform sampling of 1.28 Tbit/s and wavelength conversion of 640 Gbit/s data signals....

  16. Spectral methods for a nonlinear initial value problem involving pseudo differential operators

    International Nuclear Information System (INIS)

    Pasciak, J.E.

    1982-01-01

    Spectral methods (Fourier methods) for approximating the solution of a nonlinear initial value problem involving pseudo differential operators are defined and analyzed. A semidiscrete approximation to the nonlinear equation based on an L 2 projection is described. The semidiscrete L 2 approximation is shown to be a priori stable and convergent under sufficient decay and smoothness assumptions on the initial data. It is shown that the semidiscrete method converges with infinite order, that is, higher order decay and smoothness assumptions imply higher order error bounds. Spectral schemes based on spacial collocation are also discussed

  17. Nonlinear Lagrangian and the π N → π π π N process

    International Nuclear Information System (INIS)

    Pinto, F.A.

    1976-02-01

    A nonlinear Lagrangian is constructed involving only pions and nucleons consisting of a part invariant under the transformations of the group SU(2) (X) SU(2) and of a part which breaks this symmetry and contains an arbitrary parameter zeta introduced in order to allow the breaking of exact PCAC. The total cross-section for the process π N → π π π N at low incident energies of the incident pion, in the threshold approximation, is calculated utilizing this nonlinear Lagrangian. The parameter zeta appears in the total cross-section of the process π N → π π N also [pt

  18. Charge exchange processes involving iron ions

    International Nuclear Information System (INIS)

    Phaneuf, R.A.

    1985-01-01

    A review and evaluation is given of the experimental data which are available for charge exchange processes involving iron ions and neutral H, H 2 and He. Appropriate scaling laws are presented, and their accuracy estimated for these systems. A bibliography is given of available data sources, as well as of useful data compilations and review articles. A procedure is recommended for providing single approximate formulae to the fusion community to describe total cross sections for electron capture by partially-stripped Fe/sup q+/ ions in collisions with H, H 2 and He, based on the scaling relationships suggested by Janev and Hvelplund

  19. Nonlinear signal processing for ultrasonic imaging of material complexity

    Czech Academy of Sciences Publication Activity Database

    Dos Santos, S.; Vejvodová, Šárka; Převorovský, Zdeněk

    2010-01-01

    Roč. 59, č. 2 (2010), s. 108-117 ISSN 1736-6046 Institutional research plan: CEZ:AV0Z20760514 Keywords : nonlinear signal processing * TR-NEWS * symmetry analysis * DORT Subject RIV: BI - Acoustics Impact factor: 0.464, year: 2010 www.eap.ee/proceedings

  20. Modeling Autoregressive Processes with Moving-Quantiles-Implied Nonlinearity

    Directory of Open Access Journals (Sweden)

    Isao Ishida

    2015-01-01

    Full Text Available We introduce and investigate some properties of a class of nonlinear time series models based on the moving sample quantiles in the autoregressive data generating process. We derive a test fit to detect this type of nonlinearity. Using the daily realized volatility data of Standard & Poor’s 500 (S&P 500 and several other indices, we obtained good performance using these models in an out-of-sample forecasting exercise compared with the forecasts obtained based on the usual linear heterogeneous autoregressive and other models of realized volatility.

  1. Photonic single nonlinear-delay dynamical node for information processing

    Science.gov (United States)

    Ortín, Silvia; San-Martín, Daniel; Pesquera, Luis; Gutiérrez, José Manuel

    2012-06-01

    An electro-optical system with a delay loop based on semiconductor lasers is investigated for information processing by performing numerical simulations. This system can replace a complex network of many nonlinear elements for the implementation of Reservoir Computing. We show that a single nonlinear-delay dynamical system has the basic properties to perform as reservoir: short-term memory and separation property. The computing performance of this system is evaluated for two prediction tasks: Lorenz chaotic time series and nonlinear auto-regressive moving average (NARMA) model. We sweep the parameters of the system to find the best performance. The results achieved for the Lorenz and the NARMA-10 tasks are comparable to those obtained by other machine learning methods.

  2. Linear and Nonlinear MHD Wave Processes in Plasmas. Final Report

    International Nuclear Information System (INIS)

    Tataronis, J. A.

    2004-01-01

    This program treats theoretically low frequency linear and nonlinear wave processes in magnetized plasmas. A primary objective has been to evaluate the effectiveness of MHD waves to heat plasma and drive current in toroidal configurations. The research covers the following topics: (1) the existence and properties of the MHD continua in plasma equilibria without spatial symmetry; (2) low frequency nonresonant current drive and nonlinear Alfven wave effects; and (3) nonlinear electron acceleration by rf and random plasma waves. Results have contributed to the fundamental knowledge base of MHD activity in symmetric and asymmetric toroidal plasmas. Among the accomplishments of this research effort, the following are highlighted: Identification of the MHD continuum mode singularities in toroidal geometry. Derivation of a third order ordinary differential equation that governs nonlinear current drive in the singular layers of the Alfven continuum modes in axisymmetric toroidal geometry. Bounded solutions of this ODE implies a net average current parallel to the toroidal equilibrium magnetic field. Discovery of a new unstable continuum of the linearized MHD equation in axially periodic circular plasma cylinders with shear and incompressibility. This continuum, which we named ''accumulation continuum'' and which is related to ballooning modes, arises as discrete unstable eigenfrequency accumulate on the imaginary frequency axis in the limit of large mode numbers. Development of techniques to control nonlinear electron acceleration through the action of multiple coherent and random plasmas waves. Two important elements of this program aye student participation and student training in plasma theory

  3. Nonlinear transport processes in tokamak plasmas. I. The collisional regimes

    International Nuclear Information System (INIS)

    Sonnino, Giorgio; Peeters, Philippe

    2008-01-01

    An application of the thermodynamic field theory (TFT) to transport processes in L-mode tokamak plasmas is presented. The nonlinear corrections to the linear ('Onsager') transport coefficients in the collisional regimes are derived. A quite encouraging result is the appearance of an asymmetry between the Pfirsch-Schlueter (P-S) ion and electron transport coefficients: the latter presents a nonlinear correction, which is absent for the ions, and makes the radial electron coefficients much larger than the former. Explicit calculations and comparisons between the neoclassical results and the TFT predictions for Joint European Torus (JET) plasmas are also reported. It is found that the nonlinear electron P-S transport coefficients exceed the values provided by neoclassical theory by a factor that may be of the order 10 2 . The nonlinear classical coefficients exceed the neoclassical ones by a factor that may be of order 2. For JET, the discrepancy between experimental and theoretical results for the electron losses is therefore significantly reduced by a factor 10 2 when the nonlinear contributions are duly taken into account but, there is still a factor of 10 2 to be explained. This is most likely due to turbulence. The expressions of the ion transport coefficients, determined by the neoclassical theory in these two regimes, remain unaltered. The low-collisional regimes, i.e., the plateau and the banana regimes, are analyzed in the second part of this work

  4. Processes involved in solving mathematical problems

    Science.gov (United States)

    Shahrill, Masitah; Putri, Ratu Ilma Indra; Zulkardi, Prahmana, Rully Charitas Indra

    2018-04-01

    This study examines one of the instructional practices features utilized within the Year 8 mathematics lessons in Brunei Darussalam. The codes from the TIMSS 1999 Video Study were applied and strictly followed, and from the 183 mathematics problems recorded, there were 95 problems with a solution presented during the public segments of the video-recorded lesson sequences of the four sampled teachers. The analyses involved firstly, identifying the processes related to mathematical problem statements, and secondly, examining the different processes used in solving the mathematical problems for each problem publicly completed during the lessons. The findings revealed that for three of the teachers, their problem statements coded as `using procedures' ranged from 64% to 83%, while the remaining teacher had 40% of his problem statements coded as `making connections.' The processes used when solving the problems were mainly `using procedures', and none of the problems were coded as `giving results only'. Furthermore, all four teachers made use of making the relevant connections in solving the problems given to their respective students.

  5. A non-linear model of economic production processes

    Science.gov (United States)

    Ponzi, A.; Yasutomi, A.; Kaneko, K.

    2003-06-01

    We present a new two phase model of economic production processes which is a non-linear dynamical version of von Neumann's neoclassical model of production, including a market price-setting phase as well as a production phase. The rate of an economic production process is observed, for the first time, to depend on the minimum of its input supplies. This creates highly non-linear supply and demand dynamics. By numerical simulation, production networks are shown to become unstable when the ratio of different products to total processes increases. This provides some insight into observed stability of competitive capitalist economies in comparison to monopolistic economies. Capitalist economies are also shown to have low unemployment.

  6. Nonlinear wave-mixing processes in the extreme ultraviolet

    International Nuclear Information System (INIS)

    Misoguti, L.; Christov, I. P.; Backus, S.; Murnane, M. M.; Kapteyn, H. C.

    2005-01-01

    We present data from two-color high-order harmonic generation in a hollow waveguide, that suggest the presence of a nonlinear-optical frequency conversion process driven by extreme ultraviolet light. By combining the fundamental and second harmonic of an 800 nm laser in a hollow-core fiber, with varying relative polarizations, and by observing the pressure and power scaling of the various harmonic orders, we show that the data are consistent with a picture where we drive the process of high-harmonic generation, which in turn drives four-wave frequency mixing processes in the extreme EUV. This work promises a method for extending nonlinear optics into the extreme ultraviolet region of the spectrum using an approach that has not previously been considered, and has compelling implications for generating tunable light at short wavelengths

  7. Nonlinear processes of magnons in insulating ferromagnetic materials

    International Nuclear Information System (INIS)

    Araujo, C.B. de.

    1975-04-01

    The representation of coherent states is used to investigate the excitation of magnons by 'parallel pumping', 'perpendicular pumping' and 'phonon pumping'. The stationary regime of the processes is studied with respect to the magnon population and the statistic behavior of the system below and just above the threshold. Particular attention is given to the thermodynamic and the coherence properties of the parametric states. The results show that just above the threshold the generated states become coherent. Also, it is shown that the non-linear processes have characteristics of a second-order phase transition with the pumping power as the 'reservoir variable' and the transverse dynamical magnetization as the 'order parameter'. Finally, the possibilities to extend the theory, its experimental check, and its convenience to study the other nonlinear processes of magnons and phonons in magnetic insulators are discussed. (author) [pt

  8. Involving construction in the preliminary engineering process

    International Nuclear Information System (INIS)

    Mahoney, D.T. Jr.; Boccieri, S.V. Jr.

    1994-01-01

    With today's high cost associated with modifications in nuclear power plants, it is imperative that the authors continue to investigate ways to cut costs but at the same time improve efficiency and reduce radiation exposure to those directly associated with the implementation of modifications. The success associated with involving construction in the preliminary engineering process will not only cut costs and improve efficiency but will establish a Team Building concept to provide accountability to all those associated with the implementation of the task. This form of partnering focuses on the solutions rather than highlighting the difficulties. This paper will demonstrate techniques to implement such ideas and provide examples to corroborate actual successes already achieved

  9. A fuzzy model based adaptive PID controller design for nonlinear and uncertain processes.

    Science.gov (United States)

    Savran, Aydogan; Kahraman, Gokalp

    2014-03-01

    We develop a novel adaptive tuning method for classical proportional-integral-derivative (PID) controller to control nonlinear processes to adjust PID gains, a problem which is very difficult to overcome in the classical PID controllers. By incorporating classical PID control, which is well-known in industry, to the control of nonlinear processes, we introduce a method which can readily be used by the industry. In this method, controller design does not require a first principal model of the process which is usually very difficult to obtain. Instead, it depends on a fuzzy process model which is constructed from the measured input-output data of the process. A soft limiter is used to impose industrial limits on the control input. The performance of the system is successfully tested on the bioreactor, a highly nonlinear process involving instabilities. Several tests showed the method's success in tracking, robustness to noise, and adaptation properties. We as well compared our system's performance to those of a plant with altered parameters with measurement noise, and obtained less ringing and better tracking. To conclude, we present a novel adaptive control method that is built upon the well-known PID architecture that successfully controls highly nonlinear industrial processes, even under conditions such as strong parameter variations, noise, and instabilities. © 2013 Published by ISA on behalf of ISA.

  10. Photonic Crystal Nanocavity Devices for Nonlinear Signal Processing

    DEFF Research Database (Denmark)

    Yu, Yi

    , membranization of InP/InGaAs structure and wet etching. Experimental investigation of the switching dynamics of InP photonic crystal nanocavity structures are carried out using short-pulse homodyne pump-probe techniques, both in the linear and nonlinear region where the cavity is perturbed by a relatively small......This thesis deals with the investigation of InP material based photonic crystal cavity membrane structures, both experimentally and theoretically. The work emphasizes on the understanding of the physics underlying the structures’ nonlinear properties and their applications for all-optical signal...... processing. Based on the previous fabrication recipe developed in our III-V platform, several processing techniques are developed and optimized for the fabrication of InP photonic crystal membrane structures. Several key issues are identified to ensure a good device quality such as air hole size control...

  11. Preface "Nonlinear processes in oceanic and atmospheric flows"

    Directory of Open Access Journals (Sweden)

    E. García-Ladona

    2010-05-01

    Full Text Available Nonlinear phenomena are essential ingredients in many oceanic and atmospheric processes, and successful understanding of them benefits from multidisciplinary collaboration between oceanographers, meteorologists, physicists and mathematicians. The present Special Issue on "Nonlinear Processes in Oceanic and Atmospheric Flows" contains selected contributions from attendants to the workshop which, in the above spirit, was held in Castro Urdiales, Spain, in July 2008. Here we summarize the Special Issue contributions, which include papers on the characterization of ocean transport in the Lagrangian and in the Eulerian frameworks, generation and variability of jets and waves, interactions of fluid flow with plankton dynamics or heavy drops, scaling in meteorological fields, and statistical properties of El Niño Southern Oscillation.

  12. Nonlinear Silicon Photonic Signal Processing Devices for Future Optical Networks

    Directory of Open Access Journals (Sweden)

    Cosimo Lacava

    2017-01-01

    Full Text Available In this paper, we present a review on silicon-based nonlinear devices for all optical nonlinear processing of complex telecommunication signals. We discuss some recent developments achieved by our research group, through extensive collaborations with academic partners across Europe, on optical signal processing using silicon-germanium and amorphous silicon based waveguides as well as novel materials such as silicon rich silicon nitride and tantalum pentoxide. We review the performance of four wave mixing wavelength conversion applied on complex signals such as Differential Phase Shift Keying (DPSK, Quadrature Phase Shift Keying (QPSK, 16-Quadrature Amplitude Modulation (QAM and 64-QAM that dramatically enhance the telecom signal spectral efficiency, paving the way to next generation terabit all-optical networks.

  13. NON-LINEAR FINITE ELEMENT MODELING OF DEEP DRAWING PROCESS

    Directory of Open Access Journals (Sweden)

    Hasan YILDIZ

    2004-03-01

    Full Text Available Deep drawing process is one of the main procedures used in different branches of industry. Finding numerical solutions for determination of the mechanical behaviour of this process will save time and money. In die surfaces, which have complex geometries, it is hard to determine the effects of parameters of sheet metal forming. Some of these parameters are wrinkling, tearing, and determination of the flow of the thin sheet metal in the die and thickness change. However, the most difficult one is determination of material properties during plastic deformation. In this study, the effects of all these parameters are analyzed before producing the dies. The explicit non-linear finite element method is chosen to be used in the analysis. The numerical results obtained for non-linear material and contact models are also compared with the experiments. A good agreement between the numerical and the experimental results is obtained. The results obtained for the models are given in detail.

  14. Heterogeneous recurrence monitoring and control of nonlinear stochastic processes

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Hui, E-mail: huiyang@usf.edu; Chen, Yun [Complex Systems Monitoring, Modeling and Analysis Laboratory, University of South Florida, Tampa, Florida 33620 (United States)

    2014-03-15

    Recurrence is one of the most common phenomena in natural and engineering systems. Process monitoring of dynamic transitions in nonlinear and nonstationary systems is more concerned with aperiodic recurrences and recurrence variations. However, little has been done to investigate the heterogeneous recurrence variations and link with the objectives of process monitoring and anomaly detection. Notably, nonlinear recurrence methodologies are based on homogeneous recurrences, which treat all recurrence states in the same way as black dots, and non-recurrence is white in recurrence plots. Heterogeneous recurrences are more concerned about the variations of recurrence states in terms of state properties (e.g., values and relative locations) and the evolving dynamics (e.g., sequential state transitions). This paper presents a novel approach of heterogeneous recurrence analysis that utilizes a new fractal representation to delineate heterogeneous recurrence states in multiple scales, including the recurrences of both single states and multi-state sequences. Further, we developed a new set of heterogeneous recurrence quantifiers that are extracted from fractal representation in the transformed space. To that end, we integrated multivariate statistical control charts with heterogeneous recurrence analysis to simultaneously monitor two or more related quantifiers. Experimental results on nonlinear stochastic processes show that the proposed approach not only captures heterogeneous recurrence patterns in the fractal representation but also effectively monitors the changes in the dynamics of a complex system.

  15. Neural Generalized Predictive Control of a non-linear Process

    DEFF Research Database (Denmark)

    Sørensen, Paul Haase; Nørgård, Peter Magnus; Ravn, Ole

    1998-01-01

    The use of neural network in non-linear control is made difficult by the fact the stability and robustness is not guaranteed and that the implementation in real time is non-trivial. In this paper we introduce a predictive controller based on a neural network model which has promising stability qu...... detail and discuss the implementation difficulties. The neural generalized predictive controller is tested on a pneumatic servo sys-tem.......The use of neural network in non-linear control is made difficult by the fact the stability and robustness is not guaranteed and that the implementation in real time is non-trivial. In this paper we introduce a predictive controller based on a neural network model which has promising stability...... qualities. The controller is a non-linear version of the well-known generalized predictive controller developed in linear control theory. It involves minimization of a cost function which in the present case has to be done numerically. Therefore, we develop the numerical algorithms necessary in substantial...

  16. Nonlinear Statistical Signal Processing: A Particle Filtering Approach

    International Nuclear Information System (INIS)

    Candy, J.

    2007-01-01

    A introduction to particle filtering is discussed starting with an overview of Bayesian inference from batch to sequential processors. Once the evolving Bayesian paradigm is established, simulation-based methods using sampling theory and Monte Carlo realizations are discussed. Here the usual limitations of nonlinear approximations and non-gaussian processes prevalent in classical nonlinear processing algorithms (e.g. Kalman filters) are no longer a restriction to perform Bayesian inference. It is shown how the underlying hidden or state variables are easily assimilated into this Bayesian construct. Importance sampling methods are then discussed and shown how they can be extended to sequential solutions implemented using Markovian state-space models as a natural evolution. With this in mind, the idea of a particle filter, which is a discrete representation of a probability distribution, is developed and shown how it can be implemented using sequential importance sampling/resampling methods. Finally, an application is briefly discussed comparing the performance of the particle filter designs with classical nonlinear filter implementations

  17. Dynamical processes and epidemic threshold on nonlinear coupled multiplex networks

    Science.gov (United States)

    Gao, Chao; Tang, Shaoting; Li, Weihua; Yang, Yaqian; Zheng, Zhiming

    2018-04-01

    Recently, the interplay between epidemic spreading and awareness diffusion has aroused the interest of many researchers, who have studied models mainly based on linear coupling relations between information and epidemic layers. However, in real-world networks the relation between two layers may be closely correlated with the property of individual nodes and exhibits nonlinear dynamical features. Here we propose a nonlinear coupled information-epidemic model (I-E model) and present a comprehensive analysis in a more generalized scenario where the upload rate differs from node to node, deletion rate varies between susceptible and infected states, and infection rate changes between unaware and aware states. In particular, we develop a theoretical framework of the intra- and inter-layer dynamical processes with a microscopic Markov chain approach (MMCA), and derive an analytic epidemic threshold. Our results suggest that the change of upload and deletion rate has little effect on the diffusion dynamics in the epidemic layer.

  18. Predicting speech intelligibility in conditions with nonlinearly processed noisy speech

    DEFF Research Database (Denmark)

    Jørgensen, Søren; Dau, Torsten

    2013-01-01

    The speech-based envelope power spectrum model (sEPSM; [1]) was proposed in order to overcome the limitations of the classical speech transmission index (STI) and speech intelligibility index (SII). The sEPSM applies the signal-tonoise ratio in the envelope domain (SNRenv), which was demonstrated...... to successfully predict speech intelligibility in conditions with nonlinearly processed noisy speech, such as processing with spectral subtraction. Moreover, a multiresolution version (mr-sEPSM) was demonstrated to account for speech intelligibility in various conditions with stationary and fluctuating...

  19. Bifurcation and stability analysis of a nonlinear milling process

    Science.gov (United States)

    Weremczuk, Andrzej; Rusinek, Rafal; Warminski, Jerzy

    2018-01-01

    Numerical investigations of milling operations dynamics are presented in this paper. A two degree of freedom nonlinear model is used to study workpiece-tool vibrations. The analyzed model takes into account both flexibility of the tool and the workpiece. The dynamics of the milling process is described by the discontinuous ordinary differential equation with time delay, which can cause process instability. First, stability lobes diagrams are created on the basis of the parameters determined in impact test of an end mill and workpiece. Next, the bifurcations diagrams are performed for different values of rotational speeds.

  20. Preconditioned steepest descent methods for some nonlinear elliptic equations involving p-Laplacian terms

    Energy Technology Data Exchange (ETDEWEB)

    Feng, Wenqiang, E-mail: wfeng1@vols.utk.edu [Department of Mathematics, The University of Tennessee, Knoxville, TN 37996 (United States); Salgado, Abner J., E-mail: asalgad1@utk.edu [Department of Mathematics, The University of Tennessee, Knoxville, TN 37996 (United States); Wang, Cheng, E-mail: cwang1@umassd.edu [Department of Mathematics, The University of Massachusetts, North Dartmouth, MA 02747 (United States); Wise, Steven M., E-mail: swise1@utk.edu [Department of Mathematics, The University of Tennessee, Knoxville, TN 37996 (United States)

    2017-04-01

    We describe and analyze preconditioned steepest descent (PSD) solvers for fourth and sixth-order nonlinear elliptic equations that include p-Laplacian terms on periodic domains in 2 and 3 dimensions. The highest and lowest order terms of the equations are constant-coefficient, positive linear operators, which suggests a natural preconditioning strategy. Such nonlinear elliptic equations often arise from time discretization of parabolic equations that model various biological and physical phenomena, in particular, liquid crystals, thin film epitaxial growth and phase transformations. The analyses of the schemes involve the characterization of the strictly convex energies associated with the equations. We first give a general framework for PSD in Hilbert spaces. Based on certain reasonable assumptions of the linear pre-conditioner, a geometric convergence rate is shown for the nonlinear PSD iteration. We then apply the general theory to the fourth and sixth-order problems of interest, making use of Sobolev embedding and regularity results to confirm the appropriateness of our pre-conditioners for the regularized p-Lapacian problems. Our results include a sharper theoretical convergence result for p-Laplacian systems compared to what may be found in existing works. We demonstrate rigorously how to apply the theory in the finite dimensional setting using finite difference discretization methods. Numerical simulations for some important physical application problems – including thin film epitaxy with slope selection and the square phase field crystal model – are carried out to verify the efficiency of the scheme.

  1. Defining stakeholder involvement in participatory design processes

    NARCIS (Netherlands)

    Vink, P.; Imada, A.S.; Zink, K.J.

    2008-01-01

    A participatory approach could be used to implement work place or organizational improvements. However, the question is which participants should be involved and how. In this paper the theoretical involvement in different steps of a linear stepwise approach is described and compared with the latest

  2. Customer Involvement in the Game Development Process

    Directory of Open Access Journals (Sweden)

    Kaja Prystupa-Rządca

    2015-01-01

    Full Text Available The creative industry is a fast developing sector of economy in many countries. Growing competition in this area has led many companies to implement strategy of users' involvement in product development in order to deliver products that are more aligned with customers’ needs. On the other hand, the attempt to align the customers’ expectations with artistic creativity may create tensions. Therefore, the aim of the research is to examine the methods of users’ involvement in product development and real impact of the users on project design. The obtained findings are based on two-year qualitative research project conducted in game development companies.

  3. Control of a nonlinear ice cream crystallization process

    OpenAIRE

    Casenave, Céline; Dochain, Denis; Alvarez, Graciela; Arellano, Marcela; Benkhelifa, Hayat; Leducq, Denis

    2013-01-01

    International audience; In the ice cream industry, the type of final desired product (large cartons (sqrounds) or ice creams on a stick) determine the viscosity at which the ice cream has to be produced. One of the objectives of the ice cream crystallization processes is therefore to produce an ice cream of specified viscosity. In this paper, a nonlinear control strategy is proposed for the control of the viscosity of the ice cream in a continuous crystallizer. It has been designed on the bas...

  4. Nonlinear identification of process dynamics using neural networks

    International Nuclear Information System (INIS)

    Parlos, A.G.; Atiya, A.F.; Chong, K.T.

    1992-01-01

    In this paper the nonlinear identification of process dynamics encountered in nuclear power plant components is addressed, in an input-output sense, using artificial neural systems. A hybrid feedforward/feedback neural network, namely, a recurrent multilayer perceptron, is used as the model structure to be identified. The feedforward portion of the network architecture provides its well-known interpolation property, while through recurrency and cross-talk, the local information feedback enables representation of temporal variations in the system nonlinearities. The standard backpropagation learning algorithm is modified, and it is used for the supervised training of the proposed hybrid network. The performance of recurrent multilayer perceptron networks in identifying process dynamics is investigated via the case study of a U-tube steam generator. The response of representative steam generator is predicted using a neural network, and it is compared to the response obtained from a sophisticated computer model based on first principles. The transient responses compare well, although further research is warranted to determine the predictive capabilities of these networks during more severe operational transients and accident scenarios

  5. Hierarchical optimal control of large-scale nonlinear chemical processes.

    Science.gov (United States)

    Ramezani, Mohammad Hossein; Sadati, Nasser

    2009-01-01

    In this paper, a new approach is presented for optimal control of large-scale chemical processes. In this approach, the chemical process is decomposed into smaller sub-systems at the first level, and a coordinator at the second level, for which a two-level hierarchical control strategy is designed. For this purpose, each sub-system in the first level can be solved separately, by using any conventional optimization algorithm. In the second level, the solutions obtained from the first level are coordinated using a new gradient-type strategy, which is updated by the error of the coordination vector. The proposed algorithm is used to solve the optimal control problem of a complex nonlinear chemical stirred tank reactor (CSTR), where its solution is also compared with the ones obtained using the centralized approach. The simulation results show the efficiency and the capability of the proposed hierarchical approach, in finding the optimal solution, over the centralized method.

  6. Innovative Pedagogical Processes Involving Educational Technology

    DEFF Research Database (Denmark)

    Weitze, Charlotte Lærke

    to create motivating learning for the students. This was done by examining the three actors in the educational institution (students, teachers and the surrounding organisation) individually and relationally. The design-based research project developed knowledge in co-design processes with the three actors...

  7. Microwave heating processes involving carbon materials

    Energy Technology Data Exchange (ETDEWEB)

    Menendez, J.A.; Arenillas, A.; Fidalgo, B.; Fernandez, Y.; Zubizarreta, L.; Calvo, E.G.; Bermudez, J.M. [Instituto Nacional del Carbon, CSIC, Apartado 73, 33080 Oviedo (Spain)

    2010-01-15

    Carbon materials are, in general, very good absorbents of microwaves, i.e., they are easily heated by microwave radiation. This characteristic allows them to be transformed by microwave heating, giving rise to new carbons with tailored properties, to be used as microwave receptors, in order to heat other materials indirectly, or to act as a catalyst and microwave receptor in different heterogeneous reactions. In recent years, the number of processes that combine the use of carbons and microwave heating instead of other methods based on conventional heating has increased. In this paper some of the microwave-assisted processes in which carbon materials are produced, transformed or used in thermal treatments (generally, as microwave absorbers and catalysts) are reviewed and the main achievements of this technique are compared with those obtained by means of conventional (non microwave-assisted) methods in similar conditions. (author)

  8. Electrochemical redox processes involving soluble cerium species

    International Nuclear Information System (INIS)

    Arenas, L.F.; Ponce de León, C.; Walsh, F.C.

    2016-01-01

    Highlights: • The relevance of cerium in laboratory and industrial electrochemistry is considered. • The history of fundamental electrochemical studies and applications is considered. • The chemistry, redox thermodynamics and electrode kinetics of cerium are summarised. • The uses of cerium ions in synthesis, energy storage, analysis and environmental treatment are illustrated. • Research needs and development perspectives are discussed. - Abstract: Anodic oxidation of cerous ions and cathodic reduction of ceric ions, in aqueous acidic solutions, play an important role in electrochemical processes at laboratory and industrial scale. Ceric ions, which have been used for oxidation of organic wastes and off-gases in environmental treatment, are a well-established oxidant for indirect organic synthesis and specialised cleaning processes, including oxide film removal from tanks and process pipework in nuclear decontamination. They also provide a classical reagent for chemical analysis in the laboratory. The reversible oxidation of cerous ions is an important reaction in the positive compartment of various redox flow batteries during charge and discharge cycling. A knowledge of the thermodynamics and kinetics of the redox reaction is critical to an understanding of the role of cerium redox species in these applications. Suitable choices of electrode material (metal or ceramic; coated or uncoated), geometry/structure (2-or 3-dimensional) and electrolyte flow conditions (hence an acceptable mass transport rate) are critical to achieving effective electrocatalysis, a high performance and a long lifetime. This review considers the electrochemistry of soluble cerium species and their diverse uses in electrochemical technology, especially for redox flow batteries and mediated electrochemical oxidation.

  9. Motivational Influences on Cognition: Task Involvement, Ego Involvement, and Depth of Information Processing.

    Science.gov (United States)

    Graham, Sandra; Golan, Shari

    1991-01-01

    Task involvement and ego involvement were studied in relation to depth of information processing for 126 fifth and sixth graders in 2 experiments. Ego involvement resulted in poorer word recall at deep rather than shallow information processing levels. Implications for the study of motivation are discussed. (SLD)

  10. Nonlinear analysis and control of a continuous fermentation process

    DEFF Research Database (Denmark)

    Szederkényi, G.; Kristensen, Niels Rode; Hangos, K.M

    2002-01-01

    Different types of nonlinear controllers are designed and compared for a simple continuous bioreactor operating near optimal productivity. This operating point is located close to a fold bifurcation point. Nonlinear analysis of stability, controllability and zero dynamics is used to investigate o...... are recommended for the simple fermenter. Passivity based controllers have been found to be globally stable, not very sensitive to the uncertainties in the reaction rate and controller parameter but they require full nonlinear state feedback....

  11. Non-linear processes in the Earth atmosphere boundary layer

    Science.gov (United States)

    Grunskaya, Lubov; Valery, Isakevich; Dmitry, Rubay

    2013-04-01

    The work is connected with studying electromagnetic fields in the resonator Earth-Ionosphere. There is studied the interconnection of tide processes of geophysical and astrophysical origin with the Earth electromagnetic fields. On account of non-linear property of the resonator Earth-Ionosphere the tides (moon and astrophysical tides) in the electromagnetic Earth fields are kinds of polyharmonic nature. It is impossible to detect such non-linear processes with the help of the classical spectral analysis. Therefore to extract tide processes in the electromagnetic fields, the method of covariance matrix eigen vectors is used. Experimental investigations of electromagnetic fields in the atmosphere boundary layer are done at the distance spaced stations, situated on Vladimir State University test ground, at Main Geophysical Observatory (St. Petersburg), on Kamchatka pen., on Lake Baikal. In 2012 there was continued to operate the multichannel synchronic monitoring system of electrical and geomagnetic fields at the spaced apart stations: VSU physical experimental proving ground; the station of the Institute of Solar and Terrestrial Physics of Russian Academy of Science (RAS) at Lake Baikal; the station of the Institute of volcanology and seismology of RAS in Paratunka; the station in Obninsk on the base of the scientific and production society "Typhoon". Such investigations turned out to be possible after developing the method of scanning experimental signal of electromagnetic field into non- correlated components. There was used a method of the analysis of the eigen vectors ofthe time series covariance matrix for exposing influence of the moon tides on Ez. The method allows to distribute an experimental signal into non-correlated periodicities. The present method is effective just in the situation when energetical deposit because of possible influence of moon tides upon the electromagnetic fields is little. There have been developed and realized in program components

  12. Nonlinear closure relations theory for transport processes in nonequilibrium systems

    International Nuclear Information System (INIS)

    Sonnino, Giorgio

    2009-01-01

    A decade ago, a macroscopic theory for closure relations has been proposed for systems out of Onsager's region. This theory is referred to as the thermodynamic field theory (TFT). The aim of this work was to determine the nonlinear flux-force relations that respect the thermodynamic theorems for systems far from equilibrium. We propose a formulation of the TFT where one of the basic restrictions, namely, the closed-form solution for the skew-symmetric piece of the transport coefficients, has been removed. In addition, the general covariance principle is replaced by the De Donder-Prigogine thermodynamic covariance principle (TCP). The introduction of TCP requires the application of an appropriate mathematical formalism, which is referred to as the entropy-covariant formalism. By geometrical arguments, we prove the validity of the Glansdorff-Prigogine universal criterion of evolution. A new set of closure equations determining the nonlinear corrections to the linear ('Onsager') transport coefficients is also derived. The geometry of the thermodynamic space is non-Riemannian. However, it tends to be Riemannian for high values of the entropy production. In this limit, we recover the transport equations found by the old theory. Applications of our approach to transport in magnetically confined plasmas, materials submitted to temperature, and electric potential gradients or to unimolecular triangular chemical reactions can be found at references cited herein. Transport processes in tokamak plasmas are of particular interest. In this case, even in the absence of turbulence, the state of the plasma remains close to (but, it is not in) a state of local equilibrium. This prevents the transport relations from being linear.

  13. Real-time nonlinear feedback control of pattern formation in (bio)chemical reaction-diffusion processes: a model study.

    Science.gov (United States)

    Brandt-Pollmann, U; Lebiedz, D; Diehl, M; Sager, S; Schlöder, J

    2005-09-01

    Theoretical and experimental studies related to manipulation of pattern formation in self-organizing reaction-diffusion processes by appropriate control stimuli become increasingly important both in chemical engineering and cellular biochemistry. In a model study, we demonstrate here exemplarily the application of an efficient nonlinear model predictive control (NMPC) algorithm to real-time optimal feedback control of pattern formation in a bacterial chemotaxis system modeled by nonlinear partial differential equations. The corresponding drift-diffusion model type is representative for many (bio)chemical systems involving nonlinear reaction dynamics and nonlinear diffusion. We show how the computed optimal feedback control strategy exploits the system inherent physical property of wave propagation to achieve desired control aims. We discuss various applications of our approach to optimal control of spatiotemporal dynamics.

  14. Inferring Instantaneous, Multivariate and Nonlinear Sensitivities for the Analysis of Feedback Processes in a Dynamical System: Lorenz Model Case Study

    Science.gov (United States)

    Aires, Filipe; Rossow, William B.; Hansen, James E. (Technical Monitor)

    2001-01-01

    A new approach is presented for the analysis of feedback processes in a nonlinear dynamical system by observing its variations. The new methodology consists of statistical estimates of the sensitivities between all pairs of variables in the system based on a neural network modeling of the dynamical system. The model can then be used to estimate the instantaneous, multivariate and nonlinear sensitivities, which are shown to be essential for the analysis of the feedbacks processes involved in the dynamical system. The method is described and tested on synthetic data from the low-order Lorenz circulation model where the correct sensitivities can be evaluated analytically.

  15. Nonlinear and turbulent processes in physics. Volume 2. Nonlinear effects in various areas of science

    Energy Technology Data Exchange (ETDEWEB)

    Sagdeev, R Z

    1984-01-01

    The results of theoretical and experimental investigations of nonlinear and turbulent phenomena from a wide range of fields in physics are presented in reviews and reports. Topics examined include localized vortex formations in an ideal fluid, phase transitions in crystals, spatially nonuniform structures in condensed matter, solitons in molecular systems, the migration of quasi-particles in easily deformed crystals, bifurcations and dissipative structures in distributed kinetic systems, and structures in a nonlinear burning medium. Consideration is given to macroscopic motion generation in nonequilibrium media, the interaction of bulk and surface wave trains, near-threshold instabilities in hydrodynamics, solitons in nonlinear elastic rods with variable characteristics, the generation of solitons and vortices from chaos, and nonlinear electromagnetic-wave dissipation in an electron system.

  16. Corner-point criterion for assessing nonlinear image processing imagers

    Science.gov (United States)

    Landeau, Stéphane; Pigois, Laurent; Foing, Jean-Paul; Deshors, Gilles; Swiathy, Greggory

    2017-10-01

    Range performance modeling of optronics imagers attempts to characterize the ability to resolve details in the image. Today, digital image processing is systematically used in conjunction with the optoelectronic system to correct its defects or to exploit tiny detection signals to increase performance. In order to characterize these processing having adaptive and non-linear properties, it becomes necessary to stimulate the imagers with test patterns whose properties are similar to the actual scene image ones, in terms of dynamic range, contours, texture and singular points. This paper presents an approach based on a Corner-Point (CP) resolution criterion, derived from the Probability of Correct Resolution (PCR) of binary fractal patterns. The fundamental principle lies in the respectful perception of the CP direction of one pixel minority value among the majority value of a 2×2 pixels block. The evaluation procedure considers the actual image as its multi-resolution CP transformation, taking the role of Ground Truth (GT). After a spatial registration between the degraded image and the original one, the degradation is statistically measured by comparing the GT with the degraded image CP transformation, in terms of localized PCR at the region of interest. The paper defines this CP criterion and presents the developed evaluation techniques, such as the measurement of the number of CP resolved on the target, the transformation CP and its inverse transform that make it possible to reconstruct an image of the perceived CPs. Then, this criterion is compared with the standard Johnson criterion, in the case of a linear blur and noise degradation. The evaluation of an imaging system integrating an image display and a visual perception is considered, by proposing an analysis scheme combining two methods: a CP measurement for the highly non-linear part (imaging) with real signature test target and conventional methods for the more linear part (displaying). The application to

  17. Two-stage nonlinear filter for processing of scintigrams

    International Nuclear Information System (INIS)

    Pistor, P.; Hoener, J.; Walch, G.

    1973-01-01

    Linear filters which have been successfully used to process scintigrams can be modified in a meaningful manner by a preceding non-linear point operator, the Anscombe-transform. The advantages are: The scintigraphic noise becomes quasi-stationary and thus independent of the image. By these means the noise can be readily allowed for in the design of the convolutional operators. Transformed images with a stationary signal-to-noise ratio and a non-constant background t correspond to untransformed images with a signal-to-noise ratio that varies in certain limits. The filter chain automatically adapts to these changes. Our filter has the advantage over the majority of space-varying filters of being realizable by Fast Fourier Transform techniques. These advantages have to be paid for by reduced signal amplitude to background ratios. If the background is known, this shortcoming can be easily by-passed by processing trendfree scintigrams. If not, the filter chain should be completed by a third operator which reverses the Anscombe-transform. The Anscombe-transform influences the signal-to-noise ratio of cold spots and of hot spots in a different way. It remains an open question if this fact can be utilized to directly influence the detectability of the different kinds of spots

  18. Nonlinear quantum electrodynamic and electroweak processes in strong laser fields

    Energy Technology Data Exchange (ETDEWEB)

    Meuren, Sebastian

    2015-06-24

    Various nonlinear electrodynamic and electroweak processes in strong plane-wave laser fields are considered with an emphasis on short-pulse effects. In particular, the momentum distribution of photoproduced electron-positron pairs is calculated numerically and a semiclassical interpretation of its characteristic features is established. By proving the optical theorem, compact double-integral expressions for the total pair-creation probability are obtained and numerically evaluated. The exponential decay of the photon wave function in a plane wave is included by solving the Schwinger-Dyson equations to leading-order in the quasistatic approximation. In this respect, the polarization operator in a plane wave is investigated and its Ward-Takahashi identity verified. A classical analysis indicates that a photoproduced electron-positron pair recollides for certain initial conditions. The contributions of such recollision processes to the polarization operator are identified and calculated both analytically and numerically. Furthermore, the existence of nontrivial electron-spin dynamics induced by quantum fluctuations is verified for ultra-short laser pulses. Finally, the exchange of weak gauge bosons is considered, which is essential for neutrino-photon interactions. In particular, the axial-vector-vector coupling tensor is calculated and the so-called Adler-Bell-Jackiw (ABJ) anomaly investigated.

  19. Neurobiologically Inspired Approaches to Nonlinear Process Control and Modeling

    Science.gov (United States)

    1999-12-31

    incorporates second messenger reaction kinetics and calcium dynamics to represent the nonlinear dynamics and the crucial role of neuromodulation in local...reflex). The dynamic neuromodulation as a mechanism for the nonlinear attenuation is the novel result of this study. Ear- lier simulations have shown

  20. All-optical image processing with nonlinear liquid crystals

    Science.gov (United States)

    Hong, Kuan-Lun

    Liquid crystals are fascinating materials because of several advantages such as large optical birefringence, dielectric anisotropic, and easily compatible to most kinds of materials. Compared to the electro-optical properties of liquid crystals widely applied in displays and switching application, transparency through most parts of wavelengths also makes liquid crystals a better candidate for all-optical processing. The fast response time of liquid crystals resulting from multiple nonlinear effects, such as thermal and density effect can even make real-time processing realized. In addition, blue phase liquid crystals with spontaneously self-assembled three dimensional cubic structures attracted academic attention. In my dissertation, I will divide the whole contents into six parts. In Chapter 1, a brief introduction of liquid crystals is presented, including the current progress and the classification of liquid crystals. Anisotropy and laser induced director axis reorientation is presented in Chapter 2. In Chapter 3, I will solve the electrostrictive coupled equation and analyze the laser induced thermal and density effect in both static and dynamic ways. Furthermore, a dynamic simulation of laser induced density fluctuation is proposed by applying finite element method. In Chapter 4, two image processing setups are presented. One is the intensity inversion experiment in which intensity dependent phase modulation is the mechanism. The other is the wavelength conversion experiment in which I can read the invisible image with a visible probe beam. Both experiments are accompanied with simulations to realize the matching between the theories and practical experiment results. In Chapter 5, optical properties of blue phase liquid crystals will be introduced and discussed. The results of grating diffractions and thermal refractive index gradient are presented in this chapter. In addition, fiber arrays imaging and switching with BPLCs will be included in this chapter

  1. Convergence rates and finite-dimensional approximations for nonlinear ill-posed problems involving monotone operators in Banach spaces

    International Nuclear Information System (INIS)

    Nguyen Buong.

    1992-11-01

    The purpose of this paper is to investigate convergence rates for an operator version of Tikhonov regularization constructed by dual mapping for nonlinear ill-posed problems involving monotone operators in real reflective Banach spaces. The obtained results are considered in combination with finite-dimensional approximations for the space. An example is considered for illustration. (author). 15 refs

  2. All-optical signal processing in quadratic nonlinear materials

    DEFF Research Database (Denmark)

    Johansen, Steffen Kjær

    2002-01-01

    of materials with a second order nonlinearity, the so-called X(2) materials, is faster and stronger than that of more conventional materials with a cubic nonlinearity. The X(2) materials support spatial solitons consisting of two coupled components, the fundamental wave (FW) and its second harmonic (SH......). During this project the interaction between such spatial solitons has been investigated theoretically through perturbation theory and experimentally via numerical simulations. The outcome of this research isnew theoretical tools for quantitatively predicting the escape angle, i.e. the angle of incidence...... are dedicated to this part of the research. In chapter 4 the generality of the theoretical approach is emphasised with the derivation and verification of equivalent tools for media with a saturable nonlinearity. The strength of the X(2) nonlinearity strongly depends on the phase mismatch between the FW...

  3. Nonlinear Schrodinger elliptic systems involving exponential critical growth in R^2

    Directory of Open Access Journals (Sweden)

    Francisco S. B. Albuquerque Albuquerque

    2014-02-01

    Full Text Available This article concerns the existence and multiplicity of solutions for elliptic systems with weights, and nonlinearities having exponential critical growth. Our approach is based on the Trudinger-Moser inequality and on a minimax theorem.

  4. Democratizing Process Innovation? On Citizen Involvement in Public Sector BPM

    Science.gov (United States)

    Niehaves, Björn; Malsch, Robert

    ‘Open Innovation’ has been heavily discussed for product innovations; however, an information systems (IS) perspective on ‘process innovation’ has not yet been taken. Analyzing the example of the public sector in Germany, the paper seeks to investigate the factors that hinder and support ‘open process innovation’, a concept we define as the involvement of citizens in business process management (BPM) activities. With the help of a quantitative study (n=358), six factors are examined for their impact on citizen involvement in local government BPM initiatives. The results show that citizen involvement in reform processes is not primarily motivated by the aim of cost reduction, but rather related to legitimacy reasons and the intent to increase employee motivation. Based on these findings, implications for (design) theory and practice are discussed: Instead of detailed collaborative business processes modeling, the key of citizen involvement in public sector BPM lies in communication and mutual understanding.

  5. Nonlinear acoustic/seismic waves in earthquake processes

    International Nuclear Information System (INIS)

    Johnson, Paul A.

    2012-01-01

    Nonlinear dynamics induced by seismic sources and seismic waves are common in Earth. Observations range from seismic strong ground motion (the most damaging aspect of earthquakes), intense near-source effects, and distant nonlinear effects from the source that have important consequences. The distant effects include dynamic earthquake triggering—one of the most fascinating topics in seismology today—which may be elastically nonlinearly driven. Dynamic earthquake triggering is the phenomenon whereby seismic waves generated from one earthquake trigger slip events on a nearby or distant fault. Dynamic triggering may take place at distances thousands of kilometers from the triggering earthquake, and includes triggering of the entire spectrum of slip behaviors currently identified. These include triggered earthquakes and triggered slow, silent-slip during which little seismic energy is radiated. It appears that the elasticity of the fault gouge—the granular material located between the fault blocks—is key to the triggering phenomenon.

  6. The Application of Linear and Nonlinear Water Tanks Case Study in Teaching of Process Control

    Science.gov (United States)

    Li, Xiangshun; Li, Zhiang

    2018-02-01

    In the traditional process control teaching, the importance of passing knowledge is emphasized while the development of creative and practical abilities of students is ignored. Traditional teaching methods are not very helpful to breed a good engineer. Case teaching is a very useful way to improve students’ innovative and practical abilities. In the traditional case teaching, knowledge points are taught separately based on different examples or no examples, thus it is very hard to setup the whole knowledge structure. Though all the knowledge is learned, how to use the knowledge to solve engineering problems keeps challenging for students. In this paper, the linear and nonlinear tanks are taken as illustrative examples which involves several knowledge points of process control. The application method of each knowledge point is discussed in detail and simulated. I believe the case-based study will be helpful for students.

  7. The Photoplethismographic Signal Processed with Nonlinear Time Series Analysis Tools

    International Nuclear Information System (INIS)

    Hernandez Caceres, Jose Luis; Hong, Rolando; Garcia Lanz, Abel; Garcia Dominguez, Luis; Cabannas, Karelia

    2001-01-01

    Finger photoplethismography (PPG) signals were submitted to nonlinear time series analysis. The applied analytical techniques were: (i) High degree polynomial fitting for baseline estimation; (ii) FFT analysis for estimating power spectra; (iii) fractal dimension estimation via the Higuchi's time-domain method, and (iv) kernel nonparametric estimation for reconstructing noise free-attractors and also for estimating signal's stochastic components

  8. Mathematical models of non-linear phenomena, processes and systems: from molecular scale to planetary atmosphere

    CERN Document Server

    2013-01-01

    This book consists of twenty seven chapters, which can be divided into three large categories: articles with the focus on the mathematical treatment of non-linear problems, including the methodologies, algorithms and properties of analytical and numerical solutions to particular non-linear problems; theoretical and computational studies dedicated to the physics and chemistry of non-linear micro-and nano-scale systems, including molecular clusters, nano-particles and nano-composites; and, papers focused on non-linear processes in medico-biological systems, including mathematical models of ferments, amino acids, blood fluids and polynucleic chains.

  9. Parallel processing for nonlinear dynamics simulations of structures including rotating bladed-disk assemblies

    Science.gov (United States)

    Hsieh, Shang-Hsien

    1993-01-01

    The principal objective of this research is to develop, test, and implement coarse-grained, parallel-processing strategies for nonlinear dynamic simulations of practical structural problems. There are contributions to four main areas: finite element modeling and analysis of rotational dynamics, numerical algorithms for parallel nonlinear solutions, automatic partitioning techniques to effect load-balancing among processors, and an integrated parallel analysis system.

  10. On the integration of an ODE involving the derivative of a Preisach nonlinearity

    International Nuclear Information System (INIS)

    Flynn, D; Rasskazov, O

    2005-01-01

    We offer an algorithm for numerical integration of an ODE with a Preisach nonlinearity under the derivative on the left-hand side. Despite the exotic form, equations of that kind are important in applied disciplines, for example in terrestrial hydrology

  11. Instantaneous nonlinear assessment of complex cardiovascular dynamics by Laguerre-Volterra point process models.

    Science.gov (United States)

    Valenza, Gaetano; Citi, Luca; Barbieri, Riccardo

    2013-01-01

    We report an exemplary study of instantaneous assessment of cardiovascular dynamics performed using point-process nonlinear models based on Laguerre expansion of the linear and nonlinear Wiener-Volterra kernels. As quantifiers, instantaneous measures such as high order spectral features and Lyapunov exponents can be estimated from a quadratic and cubic autoregressive formulation of the model first order moment, respectively. Here, these measures are evaluated on heartbeat series coming from 16 healthy subjects and 14 patients with Congestive Hearth Failure (CHF). Data were gathered from the on-line repository PhysioBank, which has been taken as landmark for testing nonlinear indices. Results show that the proposed nonlinear Laguerre-Volterra point-process methods are able to track the nonlinear and complex cardiovascular dynamics, distinguishing significantly between CHF and healthy heartbeat series.

  12. Cascading second-order nonlinear processes in a lithium niobate-on-insulator microdisk.

    Science.gov (United States)

    Liu, Shijie; Zheng, Yuanlin; Chen, Xianfeng

    2017-09-15

    Whispering-gallery-mode (WGM) microcavities are very important in both fundamental science and practical applications, among which on-chip second-order nonlinear microresonators play an important role in integrated photonic functionalities. Here we demonstrate resonant second-harmonic generation (SHG) and cascaded third-harmonic generation (THG) in a lithium niobate-on-insulator (LNOI) microdisk resonator. Efficient SHG in the visible range was obtained with only several mW input powers at telecom wavelengths. THG was also observed through a cascading process, which reveals simultaneous phase matching and strong mode coupling in the resonator. Cascading of second-order nonlinear processes gives rise to an effectively large third-order nonlinearity, which makes on-chip second-order nonlinear microresonators a promising frequency converter for integrated nonlinear photonics.

  13. Investigating Individuals' Intention to be Involved in Knowledge Management Process

    OpenAIRE

    M. J.M. Razi; N. S.A. Karim

    2011-01-01

    Problem statement: Implementation of Knowledge Management (KM) process in organizations is considered as essential to be competitive in the present competitive world. Though the modern KM practices highly depend on technology, individuals (organizational members) intention to be involved in KM process plays a major role in the success. Hence, the evaluation of individuals intention is deemed as significant before the actual implementation of KM process in organizations. Nevertheless, inadequa...

  14. Markov chains of nonlinear Markov processes and an application to a winner-takes-all model for social conformity

    Energy Technology Data Exchange (ETDEWEB)

    Frank, T D [Center for the Ecological Study of Perception and Action, Department of Psychology, University of Connecticut, 406 Babbidge Road, Storrs, CT 06269 (United States)

    2008-07-18

    We discuss nonlinear Markov processes defined on discrete time points and discrete state spaces using Markov chains. In this context, special attention is paid to the distinction between linear and nonlinear Markov processes. We illustrate that the Chapman-Kolmogorov equation holds for nonlinear Markov processes by a winner-takes-all model for social conformity. (fast track communication)

  15. Markov chains of nonlinear Markov processes and an application to a winner-takes-all model for social conformity

    International Nuclear Information System (INIS)

    Frank, T D

    2008-01-01

    We discuss nonlinear Markov processes defined on discrete time points and discrete state spaces using Markov chains. In this context, special attention is paid to the distinction between linear and nonlinear Markov processes. We illustrate that the Chapman-Kolmogorov equation holds for nonlinear Markov processes by a winner-takes-all model for social conformity. (fast track communication)

  16. Global gradient estimates for divergence-type elliptic problems involving general nonlinear operators

    Science.gov (United States)

    Cho, Yumi

    2018-05-01

    We study nonlinear elliptic problems with nonstandard growth and ellipticity related to an N-function. We establish global Calderón-Zygmund estimates of the weak solutions in the framework of Orlicz spaces over bounded non-smooth domains. Moreover, we prove a global regularity result for asymptotically regular problems which are getting close to the regular problems considered, when the gradient variable goes to infinity.

  17. Perturbation and characterization of nonlinear processes: Progress report, November 15, 1983-June 1, 1987

    International Nuclear Information System (INIS)

    Swinney, H.L.; Swift, J.

    1987-01-01

    This progress report summarizes the principal accomplishments dealing with perturbation and characterization of nonlinear processes. Topics of research include Lyapunov equations, mutual information and metric entropy, the dimensions, complex dynamics and transition sequences and spatial patterns

  18. Azimuthal asymmetry in processes of nonlinear QED for linearly polarized photon

    International Nuclear Information System (INIS)

    Bajer, V.N.; Mil'shtejn, A.I.

    1994-01-01

    Cross sections of nonlinear QED processes (photon-photon scattering, photon splitting in a Coulomb field, and Delbrueck scattering) are considered for linearly polarized initial photon. The cross sections have sizeable azimuthal asymmetry. 15 refs.; 3 figs

  19. The second order extended Kalman filter and Markov nonlinear filter for data processing in interferometric systems

    International Nuclear Information System (INIS)

    Ermolaev, P; Volynsky, M

    2014-01-01

    Recurrent stochastic data processing algorithms using representation of interferometric signal as output of a dynamic system, which state is described by vector of parameters, in some cases are more effective, compared with conventional algorithms. Interferometric signals depend on phase nonlinearly. Consequently it is expedient to apply algorithms of nonlinear stochastic filtering, such as Kalman type filters. An application of the second order extended Kalman filter and Markov nonlinear filter that allows to minimize estimation error is described. Experimental results of signals processing are illustrated. Comparison of the algorithms is presented and discussed.

  20. Nonlinear radiation generation processes in the auroral acceleration region

    Directory of Open Access Journals (Sweden)

    R. Pottelette

    2017-11-01

    Full Text Available It is known from laboratory plasma experiments that double layers (DLs radiate in the electromagnetic spectrum; but this is only known qualitatively. In these experiments, it was shown that the electron beam created on the high-potential side of a DL generates nonlinear structures which couple to electromagnetic waves and act as a sender antenna. In the Earth auroral region, observations performed by auroral spacecraft have shown that DLs occur naturally in the source region of intense radio emissions called auroral kilometric radiation (AKR. Very high time-, spatial-, and temporal-resolution measurements are needed in order to characterize waves and particle distributions in the vicinity of DLs, which are moving transient structures. We report observations from the FAST satellite of a localized large-amplitude parallel electric field (∼ 300 mV m−1 recorded at the edges of the auroral density cavity. In agreement with laboratory experiments, on the high-potential side of the DL, elementary radiation events are detected. They occur substantially above the local electron gyrofrequency and are associated with the presence of electron holes. The velocity of these nonlinear structures can be derived from the measurement of the Doppler-shifted AKR frequency spectrum above the electron gyrofrequency. The generated electron holes appear as the nonlinear evolution of electrostatic waves generated by the electron–electron two-stream instability because they propagate at about half the beam velocity. It is pointed out that, in the vicinity of a DL, the shape of the electron distribution gives rise to a significant power recorded in the left-hand polarized ordinary (LO mode.

  1. An ultra-efficient nonlinear planar integrated platform for optical signal processing and generation

    DEFF Research Database (Denmark)

    Pu, Minhao; Ottaviano, Luisa; Semenova, Elizaveta

    2017-01-01

    This paper will discuss the recently developed integrated platform: AlGaAs-oninsulator and its broad range of nonlinear applications. Recent demonstrations of broadband optical signal processing and efficient frequency comb generations in this platform will be reviewed.......This paper will discuss the recently developed integrated platform: AlGaAs-oninsulator and its broad range of nonlinear applications. Recent demonstrations of broadband optical signal processing and efficient frequency comb generations in this platform will be reviewed....

  2. Real-Time Implementation of Nonlinear Optical Processing Functions.

    Science.gov (United States)

    1986-09-30

    information capacity) with the nonlinear error correction properties of associative neural nets such as the Hopfield model. Analogies between holography...symnolic ma.Ip’:ation Th.e error correcting -apart" :ty of non" ;n-ar associative merTtnies is necessary for s’uch structu-res Experimerta. results... geometrica snapes in contact ’A,.n a c-:’:ser ’Figure 51a’ ., and a spher:cal 4:verg.ng reference -eam Upion :"um’latlon of t -" c-’gram by the object beam

  3. Nonlinear dynamics of global atmospheric and earth system processes

    Science.gov (United States)

    Zhang, Taiping; Verbitsky, Mikhail; Saltzman, Barry; Mann, Michael E.; Park, Jeffrey; Lall, Upmanu

    1995-01-01

    During the grant period, the authors continued ongoing studies aimed at enhancing their understanding of the operation of the atmosphere as a complex nonlinear system interacting with the hydrosphere, biosphere, and cryosphere in response to external radiative forcing. Five papers were completed with support from the grant, representing contributions in three main areas of study: (1) theoretical studies of the interactive atmospheric response to changed biospheric boundary conditions measurable from satellites; (2) statistical-observational studies of global-scale temperature variability on interannual to century time scales; and (3) dynamics of long-term earth system changes associated with ice sheet surges.

  4. Investigation on the effect of nonlinear processes on similarity law in high-pressure argon discharges

    Science.gov (United States)

    Fu, Yangyang; Parsey, Guy M.; Verboncoeur, John P.; Christlieb, Andrew J.

    2017-11-01

    In this paper, the effect of nonlinear processes (such as three-body collisions and stepwise ionizations) on the similarity law in high-pressure argon discharges has been studied by the use of the Kinetic Global Model framework. In the discharge model, the ground state argon atoms (Ar), electrons (e), atom ions (Ar+), molecular ions (Ar2+), and fourteen argon excited levels Ar*(4s and 4p) are considered. The steady-state electron and ion densities are obtained with nonlinear processes included and excluded in the designed models, respectively. It is found that in similar gas gaps, keeping the product of gas pressure and linear dimension unchanged, with the nonlinear processes included, the normalized density relations deviate from the similarity relations gradually as the scale-up factor decreases. Without the nonlinear processes, the parameter relations are in good agreement with the similarity law predictions. Furthermore, the pressure and the dimension effects are also investigated separately with and without the nonlinear processes. It is shown that the gas pressure effect on the results is less obvious than the dimension effect. Without the nonlinear processes, the pressure and the dimension effects could be estimated from one to the other based on the similarity relations.

  5. Transport processes in magnetically confined plasmas in the nonlinear regime.

    Science.gov (United States)

    Sonnino, Giorgio

    2006-06-01

    A field theory approach to transport phenomena in magnetically confined plasmas is presented. The thermodynamic field theory (TFT), previously developed for treating the generic thermodynamic system out of equilibrium, is applied to plasmas physics. Transport phenomena are treated here as the effect of the field linking the thermodynamic forces with their conjugate flows combined with statistical mechanics. In particular, the Classical and the Pfirsch-Schluter regimes are analyzed by solving the thermodynamic field equations of the TFT in the weak-field approximation. We found that, the TFT does not correct the expressions of the ionic heat fluxes evaluated by the neoclassical theory in these two regimes. On the other hand, the fluxes of matter and electronic energy (heat flow) is further enhanced in the nonlinear Classical and Pfirsch-Schluter regimes. These results seem to be in line with the experimental observations. The complete set of the electronic and ionic transport equations in the nonlinear Banana regime, is also reported. A paper showing the comparison between our theoretic results and the experimental observations in the JET machine is currently in preparation.

  6. Nonlinear processes in laser heating of chemically active media

    Energy Technology Data Exchange (ETDEWEB)

    Bunkin, F V; Kirichenko, N A; Luk' yanchuk, B S

    1984-08-01

    After it had been discovered and in due measure physically comprehended that numerous nontrivial phenomena observed during laser heating of chemically active media are caused primarily by self-stress of laser radiation due to the chemical intertial nonlinearity of the medium, an approach was found for solving problems of laser thermochemistry that is most adequate from the mathematical (and physical) standpoint: the approach of the theory of nonlinear oscillations in point systems and distributed systems. This approach has provided a uniform viewpoint for examination of a variety of phenomena of spatiotemporal self-organization of chemically active media under the effect of laser radiation, qualitative, and in some cases quantitative description of such phenomena as the onset of thermochemical instability, self-oscillations, various spatial structures and the like. Evidently it can be rightly considered that at this juncture a definite stage has been completed in the development of laser thermochemistry marked by the creation of an ideology, method and overall approach to interpretation of the most diverse phenomena under conditions of actual physical experiments. References to the numerous studies that make up the content of this stage of development of laser thermochemistry are to be found in survey papers. 48 references, 10 figures.

  7. Secretory processes involved in the formation of milk

    International Nuclear Information System (INIS)

    Knutsson, P.G.

    1976-01-01

    Current knowledge on milk formation is reviewed. Emphasis is given to sites of formation of protein, fat and lactose, and transfer of these compounds into the alveolar lumen. Further, the formation of the water phase of milk is thoroughly discussed, and evidence presented that milk formation includes both secretory and re-absorptive processes as well as diffusion. A short presentation of colostrum formation is included. Neither biochemical processes involved in synthesis of organic compounds nor mammary gland endocrinology are discussed. (author)

  8. One-dimensional singular problems involving the p-Laplacian and nonlinearities indefinite in sign

    OpenAIRE

    Kaufmann, Uriel; Medri, Iván

    2015-01-01

    Let $\\Omega$ be a bounded open interval, let $p>1$ and $\\gamma>0$, and let $m:\\Omega\\rightarrow\\mathbb{R}$ be a function that may change sign in $\\Omega $. In this article we study the existence and nonexistence of positive solutions for one-dimensional singular problems of the form $-(\\left\\vert u^{\\prime}\\right\\vert ^{p-2}u^{\\prime})^{\\prime}=m\\left( x\\right) u^{-\\gamma}$ in $\\Omega$, $u=0$ on $\\partial\\Omega$. As a consequence we also derive existence results for other related nonlinearities.

  9. Stakeholders involvement in the decommissioning processes in Italy

    International Nuclear Information System (INIS)

    Dionisi, Mario

    2006-01-01

    The aim of this paper is to present the situation about stakeholders involvement in Italy in the framework of the decommissioning process of the Italian nuclear installations, and in particular the specific experience of the Italian Regulatory Body APAT. Specific aspects and APAT initiatives for building confidence of stakeholders in the process of the release of solid material from the regulatory control are presented. Content: Decommissioning activities in Italy, Decommissioning licensing procedures (Site and material release, APAT - ARPA Partnership approach in the clearance process)

  10. Nonlinear model predictive control for chemical looping process

    Science.gov (United States)

    Joshi, Abhinaya; Lei, Hao; Lou, Xinsheng

    2017-08-22

    A control system for optimizing a chemical looping ("CL") plant includes a reduced order mathematical model ("ROM") that is designed by eliminating mathematical terms that have minimal effect on the outcome. A non-linear optimizer provides various inputs to the ROM and monitors the outputs to determine the optimum inputs that are then provided to the CL plant. An estimator estimates the values of various internal state variables of the CL plant. The system has one structure adapted to control a CL plant that only provides pressure measurements in the CL loops A and B, a second structure adapted to a CL plant that provides pressure measurements and solid levels in both loops A, and B, and a third structure adapted to control a CL plant that provides full information on internal state variables. A final structure provides a neural network NMPC controller to control operation of loops A and B.

  11. Unusual nonlinear absorption response of graphene oxide in the presence of a reduction process

    International Nuclear Information System (INIS)

    Karimzadeh, Rouhollah; Arandian, Alireza

    2015-01-01

    The nonlinear absorption responses of graphene, graphene oxide and reduced graphene oxide are investigated using the Z-scan technique and laser beams at 405, 532 and 635 nm in a continuous wave regime. Results show that graphene, graphene oxide and reduced graphene oxide do not show any open Z-scan signals at wavelengths of 532 and 635 nm. At the same time, fresh graphene oxide suspension is found to exhibit a nonlinear absorption process in the case of a laser light at 405 nm. Moreover, it can be observed that the reduction of graphene oxide by 405 nm laser irradiation decreases its nonlinear absorption value significantly. These findings highlight the important role of the reduction process on the nonlinear absorption performance of graphene oxide. (letter)

  12. Acoustic wave focusing in complex media using Nonlinear Time Reversal coded signal processing

    Czech Academy of Sciences Publication Activity Database

    Dos Santos, S.; Dvořáková, Zuzana; Lints, M.; Kůs, V.; Salupere, A.; Převorovský, Zdeněk

    2014-01-01

    Roč. 19, č. 12 (2014) ISSN 1435-4934. [European Conference on Non-Destructive Testing (ECNDT 2014) /11./. Praha, 06.10.2014-10.10.2014] Institutional support: RVO:61388998 Keywords : ultrasonic testing (UT) * signal processing * TR- NEWS * nonlinear time reversal * NDT * nonlinear acoustics Subject RIV: BI - Acoustics http://www.ndt.net/events/ECNDT2014/app/content/Slides/590_DosSantos_Rev1.pdf

  13. Nonlinear and Nonsymmetric Single-Molecule Electronic Properties Towards Molecular Information Processing.

    Science.gov (United States)

    Tamaki, Takashi; Ogawa, Takuji

    2017-09-05

    This review highlights molecular design for nonlinear and nonsymmetric single-molecule electronic properties such as rectification, negative differential resistance, and switching, which are important components of future single-molecule information processing devices. Perspectives on integrated "molecular circuits" are also provided. Nonlinear and nonsymmetric single-molecule electronics can be designed by utilizing (1) asymmetric molecular cores, (2) asymmetric anchoring groups, (3) an asymmetric junction environment, and (4) asymmetric electrode materials. This review mainly focuses on the design of molecular cores.

  14. Simulations of the Ocean Response to a Hurricane: Nonlinear Processes

    KAUST Repository

    Zedler, Sarah E.

    2009-10-01

    Superinertial internal waves generated by a tropical cyclone can propagate vertically and laterally away from their local generation site and break, contributing to turbulent vertical mixing in the deep ocean and maintenance of the stratification of the main thermocline. In this paper, the results of a modeling study are reported to investigate the mechanism by which superinertial fluctuations are generated in the deep ocean. The general properties of the superinertial wave wake were also characterized as a function of storm speed and central latitude. The Massachusetts Institute of Technology (MIT) Ocean General Circulation Model (OGCM) was used to simulate the open ocean response to realistic westward-tracking hurricane-type surface wind stress and heat and net freshwater buoyancy forcing for regions representative of midlatitudes in the Atlantic, the Caribbean, and low latitudes in the eastern Pacific. The model had high horizontal [Δ(x, y) = 1/6°] and vertical (Δz = 5 m in top 100 m) resolution and employed a parameterization for vertical mixing induced by shear instability. In the horizontal momentum equation, the relative size of the nonlinear advection terms, which had a dominant frequency near twice the inertial, was large only in the upper 200 m of water. Below 200 m, the linear momentum equations obeyed a linear balance to 2%. Fluctuations at nearly twice the inertial frequency (2f) were prevalent throughout the depth of the water column, indicating that these nonlinear advection terms in the upper 200 m forced a linear mode below at nearly twice the inertial frequency via vorticity conservation. Maximum variance at 2f in horizontal velocity occurred on the south side of the track. This was in response to vertical advection of northward momentum, which in the north momentum equation is an oscillatory positive definite term that constituted a net force to the south at a frequency near 2f. The ratio of this term to the Coriolis force was larger on the

  15. Nonlinearities in the quantum measurement process of superconducting qubits

    International Nuclear Information System (INIS)

    Serban, Ioana

    2008-05-01

    The work described in this thesis focuses on the investigation of decoherence and measurement backaction, on the theoretical description of measurement schemes and their improvement. The study presented here is centered around quantum computing implementations using superconducting devices and most important, the Josephson effect. The measured system is invariantly a qubit, i. e. a two-level system. The objective is to study detectors with increasing nonlinearity, e. g. coupling of the qubit to the frequency a driven oscillator, or to the bifurcation amplifier, to determine the performance and backaction of the detector on the measured system and to investigate the importance of a strong qubit-detector coupling for the achievement of a quantum non-demolition type of detection. The first part gives a very basic introduction to quantum information, briefly reviews some of the most promising physical implementations of a quantum computer before focusing on the superconducting devices. The second part presents a series of studies of different qubit measurements, describing the backaction of the measurement onto the measured system and the internal dynamics of the detector. Methodology adapted from quantum optics and chemical physics (master equations, phase-space analysis etc.) combined with the representation of a complex environment yielded a tool capable of describing a nonlinear, non-Markovian environment, which couples arbitrarily strongly to the measured system. This is described in chapter 3. Chapter 4 focuses on the backaction on the qubit and presents novel insights into the qubit dephasing in the strong coupling regime. Chapter 5 uses basically the same system and technical tools to explore the potential of a fast, strong, indirect measurement, and determine how close such a detection would ideally come to the quantum non-demolition regime. Chapter 6 focuses on the internal dynamics of a strongly driven Josephson junction. The analytical results are based on

  16. Nonlinearities in the quantum measurement process of superconducting qubits

    Energy Technology Data Exchange (ETDEWEB)

    Serban, Ioana

    2008-05-15

    The work described in this thesis focuses on the investigation of decoherence and measurement backaction, on the theoretical description of measurement schemes and their improvement. The study presented here is centered around quantum computing implementations using superconducting devices and most important, the Josephson effect. The measured system is invariantly a qubit, i. e. a two-level system. The objective is to study detectors with increasing nonlinearity, e. g. coupling of the qubit to the frequency a driven oscillator, or to the bifurcation amplifier, to determine the performance and backaction of the detector on the measured system and to investigate the importance of a strong qubit-detector coupling for the achievement of a quantum non-demolition type of detection. The first part gives a very basic introduction to quantum information, briefly reviews some of the most promising physical implementations of a quantum computer before focusing on the superconducting devices. The second part presents a series of studies of different qubit measurements, describing the backaction of the measurement onto the measured system and the internal dynamics of the detector. Methodology adapted from quantum optics and chemical physics (master equations, phase-space analysis etc.) combined with the representation of a complex environment yielded a tool capable of describing a nonlinear, non-Markovian environment, which couples arbitrarily strongly to the measured system. This is described in chapter 3. Chapter 4 focuses on the backaction on the qubit and presents novel insights into the qubit dephasing in the strong coupling regime. Chapter 5 uses basically the same system and technical tools to explore the potential of a fast, strong, indirect measurement, and determine how close such a detection would ideally come to the quantum non-demolition regime. Chapter 6 focuses on the internal dynamics of a strongly driven Josephson junction. The analytical results are based on

  17. Coherent control of photoabsorption processes and calculation of nonlinear optical processes. Final technical report

    International Nuclear Information System (INIS)

    Lambropoulos, P.

    1998-01-01

    The work on the grant for the entire period of its duration concentrated on two different but related areas, namely coherent control of photoabsorption processes and the calculation of non linear optical processes with short wavelength radiation. On the first topic, the work dealt with the problem of controlling the population transfer from one to another bound state of a system in a route that passes through a continuum. This question is most important in the context of transferring populations between vibrational states of a molecule through a sequence of two pulses taking the system via the dissociation continuum. On the second topic, their work was motivated by the availability of XUV and soft X-ray coherent radiation sources obtained through high order harmonic generation. In addition, a few other techniques based on schemes of photo-pumped X-ray lasers promise to provide in the near-future similarly coherent sources. It is thus important to have an assessment of the possibility of extending non-linear optical processes to this range of wavelengths. This means assessing the relevant magnitude of the susceptibilities for third harmonic generation, stimulated Raman scattering, two-photon absorption, etc

  18. Fault detection in nonlinear chemical processes based on kernel entropy component analysis and angular structure

    Energy Technology Data Exchange (ETDEWEB)

    Jiang, Qingchao; Yan, Xuefeng; Lv, Zhaomin; Guo, Meijin [East China University of Science and Technology, Shanghai (China)

    2013-06-15

    Considering that kernel entropy component analysis (KECA) is a promising new method of nonlinear data transformation and dimensionality reduction, a KECA based method is proposed for nonlinear chemical process monitoring. In this method, an angle-based statistic is designed because KECA reveals structure related to the Renyi entropy of input space data set, and the transformed data sets are produced with a distinct angle-based structure. Based on the angle difference between normal status and current sample data, the current status can be monitored effectively. And, the confidence limit of the angle-based statistics is determined by kernel density estimation based on sample data of the normal status. The effectiveness of the proposed method is demonstrated by case studies on both a numerical process and a simulated continuous stirred tank reactor (CSTR) process. The KECA based method can be an effective method for nonlinear chemical process monitoring.

  19. Fault detection in nonlinear chemical processes based on kernel entropy component analysis and angular structure

    International Nuclear Information System (INIS)

    Jiang, Qingchao; Yan, Xuefeng; Lv, Zhaomin; Guo, Meijin

    2013-01-01

    Considering that kernel entropy component analysis (KECA) is a promising new method of nonlinear data transformation and dimensionality reduction, a KECA based method is proposed for nonlinear chemical process monitoring. In this method, an angle-based statistic is designed because KECA reveals structure related to the Renyi entropy of input space data set, and the transformed data sets are produced with a distinct angle-based structure. Based on the angle difference between normal status and current sample data, the current status can be monitored effectively. And, the confidence limit of the angle-based statistics is determined by kernel density estimation based on sample data of the normal status. The effectiveness of the proposed method is demonstrated by case studies on both a numerical process and a simulated continuous stirred tank reactor (CSTR) process. The KECA based method can be an effective method for nonlinear chemical process monitoring

  20. Noise removal in extended depth of field microscope images through nonlinear signal processing.

    Science.gov (United States)

    Zahreddine, Ramzi N; Cormack, Robert H; Cogswell, Carol J

    2013-04-01

    Extended depth of field (EDF) microscopy, achieved through computational optics, allows for real-time 3D imaging of live cell dynamics. EDF is achieved through a combination of point spread function engineering and digital image processing. A linear Wiener filter has been conventionally used to deconvolve the image, but it suffers from high frequency noise amplification and processing artifacts. A nonlinear processing scheme is proposed which extends the depth of field while minimizing background noise. The nonlinear filter is generated via a training algorithm and an iterative optimizer. Biological microscope images processed with the nonlinear filter show a significant improvement in image quality and signal-to-noise ratio over the conventional linear filter.

  1. Polarization dependent dispersion and its impact on optical parametric process in high nonlinear microstructure fibre

    International Nuclear Information System (INIS)

    Xiao Li; Zhang Wei; Huang Yidong; Peng Jiangde

    2008-01-01

    High nonlinear microstructure fibre (HNMF) is preferred in nonlinear fibre optics, especially in the applications of optical parametric effects, due to its high optical nonlinear coefficient. However, polarization dependent dispersion will impact the nonlinear optical parametric process in HNMFs. In this paper, modulation instability (MI) method is used to measure the polarization dependent dispersion of a piece of commercial HNMF, including the group velocity dispersion, the dispersion slope, the fourth-order dispersion and group birefringence. It also experimentally demonstrates the impact of the polarization dependent dispersion on the continuous wave supercontinuum (SC) generation. On one axis MI sidebands with symmetric frequency detunings are generated, while on the other axis with larger MI frequency detuning, SC is generated by soliton self-frequency shift

  2. EARLY READING ASSESSMENT INSTRUMENTS: ABILITIES AND PROCESSES INVOLVED

    Directory of Open Access Journals (Sweden)

    Ana Cláudia de Souza

    2017-04-01

    Full Text Available This study investigates the following early reading assessment instruments: “Bateria de Recepção e Produção da Linguagem Verbal” (SCLIAR-CABRAL, 2003a and “Teste de Competência de Leitura de Palavras e Pseudopalavras” (SEABRA; CAPOVILLA, 2010. The main research goal is to analyze in each one of these reading assessment instruments some of the multiple cognitive processes and basic low-level abilities involved in reading. In this sense, decoding, word recognition, lexical access, syntactic and textual processing, and comprehension are the cognitive processes taken into account. With regard to the basic reading abilities, accuracy and fluency (rhythm, prosody and speed are considered. The results indicate that each one of the analyzed reading assessment instruments assesses different aspects of the reading processes and abilities, mainly through off-line measures. ScliarCabral’s assessment battery allows the researcher or the teacher to evaluate the following processes: perception of the grapheme opposition in minimal pairs of words and in sentences, difficulties in sentence processing, skills in decoding the graphemic-phonemic relationship, and textual comprehension. In its turn, the reading assessment instrument proposed by Seabra e Capovilla allows one to evaluate student’s reading development level, by classifying the kind of processing as logographic, alphabetic or orthographic.

  3. Public involvement in decision making process in nuclear field

    International Nuclear Information System (INIS)

    Constantin, M.; Diaconu, D.

    2009-01-01

    Decision Making Process (DMP) in nuclear field is influenced by multiple factors such as: complex technical aspects, diversity of stakeholders, long term risks, psychological stresses, societal attitudes, etc. General public is sometimes considered as the only one of stakeholders, the involvement of the public being seen as a factor to obtain the acceptance in the late phase of DMP. Generally it is assessed by public consultation on the environment impact studies and by approval of the sitting through the local authorities decision. Modern society uses methods to involve public from the beginning of DMP. The paper shows a general view of the methods and tools used in Europe for public involvement in DMP. The process of construction of a continuous democratic dialog inside of Romanian Stakeholder Group (RSG) in the frame of the FP6-COWAM2 and CIP projects is presented with a focusing of the barriers and factors of disturbing the trust and collaboration between stakeholders. The influence on the public acceptance is also discussed. (authors)

  4. Impurity-defect induced noncentrosymmetricity in nonlinear optical processes

    International Nuclear Information System (INIS)

    Miah, M. Idrish

    2009-01-01

    Noncentrosymmetric nanosize-material processes in cadmium iodide are formed by doping it with the impurity copper. The noncentrosymmetricity in the processes are probed by the observation of the second-order optical susceptibility χ ijk (2) . The value of χ ijk (2) is found to depend fashionably on the impurity content of the nanomaterials. The results also show that a significant enhancement in the noncentrosymmetric response is achieved in nanomaterials with reduced sizes and at low temperatures.

  5. Quasilinear Extreme Learning Machine Model Based Internal Model Control for Nonlinear Process

    Directory of Open Access Journals (Sweden)

    Dazi Li

    2015-01-01

    Full Text Available A new strategy for internal model control (IMC is proposed using a regression algorithm of quasilinear model with extreme learning machine (QL-ELM. Aimed at the chemical process with nonlinearity, the learning process of the internal model and inverse model is derived. The proposed QL-ELM is constructed as a linear ARX model with a complicated nonlinear coefficient. It shows some good approximation ability and fast convergence. The complicated coefficients are separated into two parts. The linear part is determined by recursive least square (RLS, while the nonlinear part is identified through extreme learning machine. The parameters of linear part and the output weights of ELM are estimated iteratively. The proposed internal model control is applied to CSTR process. The effectiveness and accuracy of the proposed method are extensively verified through numerical results.

  6. Impurity-defect induced noncentrosymmetricity in nonlinear optical processes

    Energy Technology Data Exchange (ETDEWEB)

    Miah, M. Idrish, E-mail: m.miah@griffith.edu.au [Queensland Micro- and Nanotechnology Centre, Griffith University, Nathan, Brisbane, QLD 4111 (Australia); School of Biomolecular and Physical Sciences, Griffith University, Nathan, Brisbane, QLD 4111 (Australia); Department of Physics, University of Chittagong, Chittagong 4331 (Bangladesh)

    2009-12-15

    Noncentrosymmetric nanosize-material processes in cadmium iodide are formed by doping it with the impurity copper. The noncentrosymmetricity in the processes are probed by the observation of the second-order optical susceptibility {chi}{sub ijk}{sup (2)}. The value of {chi}{sub ijk}{sup (2)} is found to depend fashionably on the impurity content of the nanomaterials. The results also show that a significant enhancement in the noncentrosymmetric response is achieved in nanomaterials with reduced sizes and at low temperatures.

  7. Discretisation of the non-linear heat transfer equation for food freezing processes using orthogonal collocation on finite elements

    Directory of Open Access Journals (Sweden)

    E. D. Resende

    2007-09-01

    Full Text Available The freezing process is considered as a propagation problem and mathematically classified as an "initial value problem." The mathematical formulation involves a complex situation of heat transfer with simultaneous changes of phase and abrupt variation in thermal properties. The objective of the present work is to solve the non-linear heat transfer equation for food freezing processes using orthogonal collocation on finite elements. This technique has not yet been applied to freezing processes and represents an alternative numerical approach in this area. The results obtained confirmed the good capability of the numerical method, which allows the simulation of the freezing process in approximately one minute of computer time, qualifying its application in a mathematical optimising procedure. The influence of the latent heat released during the crystallisation phenomena was identified by the significant increase in heat load in the early stages of the freezing process.

  8. Emission sensitization processes involving Nd{sup 3+} in YAG

    Energy Technology Data Exchange (ETDEWEB)

    Lupei, V., E-mail: lupei_voicu@yahoo.com [National Institute of Laser, Plasma and Radiation Physics, Bucharest 077125 (Romania); Lupei, A.; Gheorghe, C. [National Institute of Laser, Plasma and Radiation Physics, Bucharest 077125 (Romania); Ikesue, A. [World Lab. Co., Nagoya (Japan)

    2016-02-15

    The paper investigates the characteristics of sensitization processes of Nd{sup 3+} emission in YAG ceramics under broad band pumping by co-doping with Cr{sup 3+} and the prospect of using Nd{sup 3+} and Cr{sup 3+} for sensitization of emission of Yb{sup 3+}. It is evidenced that the energy transfer from Cr{sup 3+} to Nd{sup 3+} involves both direct and weak migration-assisted processes and is thus dependent on the concentrations of both species. It is also found that the ion–ion interaction responsible for the direct transfer contains besides the dipole–dipole coupling strong superexchange contribution that dominates the transfer to the Nd{sup 3+} ions up to the third coordination sphere and has major implication in sensitization. Investigation of (Cr, Nd, Yb)-doped YAG ceramics shows that Cr{sup 3+} can sensitize the emission of Yb{sup 3+} both via the chain Cr–Nd–Yb or by direct Cr–Yb energy transfer. The prospect of utilization of these processes in the solar-pumped laser is discussed. - Highlights: • The efficiency of sensitization increases at high Cr and Nd doping concentrations. • The Cr-to-Nd energy transfer involves both direct and migration-assisted processes. • The direct transfer implies both dipole–dipole and superexchange interactions. • The superexchange interaction has major influence on sensitization. • Sensitized emission of Yb{sup 3+} in (Cr,Nd,Yb):YAG by Cr–Nd–Yb and Cr–Yb transfers.

  9. Simultaneous spatial and temporal focusing: a route towards confined nonlinear materials processing

    Science.gov (United States)

    Kammel, Robert; Bergner, Klaus; Thomas, Jens; Ackermann, Roland; Skupin, Stefan; Nolte, Stefan

    2016-03-01

    Ultrashort pulse lasers enable reliable and versatile high precision ablation and surface processing of various materials such as metals, polymers and semiconductors. However, when modifications deep inside the bulk of transparent media are required, nonlinear pulse material interactions can decrease the precision, since weak focusing and the long propagation of the intense pulses within the nonlinear media may induce Kerr self-focusing, filamentation and white light generation. In order to improve the precision of those modifications, simultaneous spatial and temporal focusing (SSTF) allows to reduce detrimental nonlinear interactions, because the ultrashort pulse duration is only obtained at the focus, while outside of the focal region the continuously increasing pulse duration strongly reduces the pulse intensity. In this paper, we review the fundamental concepts of this technology and provide an overview of its applications for purposes of multiphoton microscopy and laser materials processing. Moreover, numerical simulations on the nonlinear pulse propagation within transparent media illustrate the linear and nonlinear pulse propagation, highlighting the differences between conventional focusing and SSTF. Finally, fs-laser induced modifications in gelatine are presented to compare nonlinear side-effects caused by conventional focusing and SSTF. With conventional focusing the complex interplay of self-focusing and filamentation induces strongly inhomogeneous, elongated disruptions. In contrast, disruptions induced by SSTF are homogeneously located at the focal plane and reduced in length by a factor >2, which is in excellent agreement with the numerical simulations of the nonlinear pulse propagation and might favor SSTF for demanding applications such as intraocular fs-laser surgery.

  10. Understanding the cognitive processes involved in writing to learn.

    Science.gov (United States)

    Arnold, Kathleen M; Umanath, Sharda; Thio, Kara; Reilly, Walter B; McDaniel, Mark A; Marsh, Elizabeth J

    2017-06-01

    Writing is often used as a tool for learning. However, empirical support for the benefits of writing-to-learn is mixed, likely because the literature conflates diverse activities (e.g., summaries, term papers) under the single umbrella of writing-to-learn. Following recent trends in the writing-to-learn literature, the authors focus on the underlying cognitive processes. They draw on the largely independent writing-to-learn and cognitive psychology learning literatures to identify important cognitive processes. The current experiment examines learning from 3 writing tasks (and 1 nonwriting control), with an emphasis on whether or not the tasks engaged retrieval. Tasks that engaged retrieval (essay writing and free recall) led to better final test performance than those that did not (note taking and highlighting). Individual differences in structure building (the ability to construct mental representations of narratives; Gernsbacher, Varner, & Faust, 1990) modified this effect; skilled structure builders benefited more from essay writing and free recall than did less skilled structure builders. Further, more essay-like responses led to better performance, implicating the importance of additional cognitive processes such as reorganization and elaboration. The results highlight how both task instructions and individual differences affect the cognitive processes involved when writing-to-learn, with consequences for the effectiveness of the learning strategy. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  11. Time evolution of absorption process in nonlinear metallic photonic crystals

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Mahi R.; Hatef, Ali [Department of Physics and Astronomy, University of Western Ontario, London (Canada)

    2009-05-15

    The time evolution of the absorption coefficient in metallic photonic crystals has been studied numerically. These crystals are made from metallic spheres which are arranged periodically in air. The refractive index of the metallic spheres depends on the plasma frequency. Probe and pump fields are applied to monitor the absorption process. Ensembles of three-level particles are embedded in the crystal. Nanoparticles are interacting with the metallic crystals via the electron-photon interaction. It is found that when the resonance states lie away from the band edges system goes to transparent state. (copyright 2009 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  12. On existence and multiplicity for Schrödinger–Poisson systems involving weighted sublinear nonlinearities

    Directory of Open Access Journals (Sweden)

    Sara Barile

    2017-04-01

    where $V, K: \\mathbb{R}^3 \\rightarrow \\mathbb{R}^+$ are suitable potentials and $f: \\mathbb{R}^3 \\times \\mathbb{R} \\rightarrow \\mathbb{R}$ satisfies sublinear growth assumptions involving a finite number of positive weights $W_i$, $i= 1,\\dots,r$ with $r \\geq 1$. By exploiting compact embeddings of the functional space on which we work in every weighted space $L_{W_i}^{w_i}(\\mathbb{R}^3$, $w_i \\in (1, 2$, we establish existence by means of a generalized Weierstrass theorem. Moreover, we prove multiplicity of solutions if $f$ is odd in $u$ and $g(x \\equiv 0$ thanks to a variant of the symmetric mountain pass theorem stated by R. Kajikiya for subquadratic functionals.

  13. The method of varying amplitudes for solving (non)linear problems involving strong parametric excitation

    DEFF Research Database (Denmark)

    Sorokin, Vladislav; Thomsen, Jon Juel

    2015-01-01

    Parametrically excited systems appear in many fields of science and technology, intrinsically or imposed purposefully; e.g. spatially periodic structures represent an important class of such systems [4]. When the parametric excitation can be considered weak, classical asymptotic methods like...... the method of averaging [2] or multiple scales [6] can be applied. However, with many practically important applications this simplification is inadequate, e.g. with spatially periodic structures it restricts the possibility to affect their effective dynamic properties by a structural parameter modulation...... of considerable magnitude. Approximate methods based on Floquet theory [4] for analyzing problems involving parametric excitation, e.g. the classical Hill’s method of infinite determinants [3,4], can be employed also in cases of strong excitation; however, with Floquet theory being applicable only for linear...

  14. Ishikawa iteration process for nonlinear Lipschitz strongly accretive mappings

    International Nuclear Information System (INIS)

    Chidume, C.E.; Osilike, M.O.

    1994-05-01

    Let E=L p , p≥2 and let T:E→ E be a Lipschitzian and strongly accretive mapping. Let S:E → E be defined by Sx=f-Tx+x. It is proved that under suitable conditions on the real sequences {α n } ∞ n=0 and {β n } ∞ n=0 , the iteration process, x 0 is an element of E, x n+1 =(1-α n ) x n +α n S[(1-β n ) x n +β n Sx n ], n≥0, converges strongly to the unique solution of Tx=f. A related result deals with the iterative approximation of fixed points for Lipschitz strongly pseudocontractive mappings in E. A consequence of our results gives an affirmative answer to a problem posed by one of the authors in 1990. (J. Math. Anal. Appl. 151, 2 (1990) p. 460). (author). 36 refs

  15. Motor cortical processing is causally involved in object recognition.

    Science.gov (United States)

    Decloe, Rebecca; Obhi, Sukhvinder S

    2013-12-14

    Motor activity during vicarious experience of actions is a widely reported and studied phenomenon, and motor system activity also accompanies observation of graspable objects in the absence of any actions. Such motor activity is thought to reflect simulation of the observed action, or preparation to interact with the object, respectively. Here, in an initial exploratory study, we ask whether motor activity during observation of object directed actions is involved in processes related to recognition of the object after initial exposure. Single pulse Transcranial Magnetic Stimulation (TMS) was applied over the thumb representation of the motor cortex, or over the vertex, during observation of a model thumb typing on a cell-phone, and performance on a phone recognition task at the end of the trial was assessed. Disrupting motor processing over the thumb representation 100 ms after the onset of the typing video impaired the ability to recognize the phone in the recognition test, whereas there was no such effect for TMS applied over the vertex and no TMS trials. Furthermore, this effect only manifested for videos observed from the first person perspective. In an additional control condition, there was no evidence for any effects of TMS to the thumb representation or vertex when observing and recognizing non-action related shape stimuli. Overall, these data provide evidence that motor cortical processing during observation of object-directed actions from a first person perspective is causally linked to the formation of enduring representations of objects-of-action.

  16. Motor cortical processing is causally involved in object recognition

    Science.gov (United States)

    2013-01-01

    Background Motor activity during vicarious experience of actions is a widely reported and studied phenomenon, and motor system activity also accompanies observation of graspable objects in the absence of any actions. Such motor activity is thought to reflect simulation of the observed action, or preparation to interact with the object, respectively. Results Here, in an initial exploratory study, we ask whether motor activity during observation of object directed actions is involved in processes related to recognition of the object after initial exposure. Single pulse Transcranial Magnetic Stimulation (TMS) was applied over the thumb representation of the motor cortex, or over the vertex, during observation of a model thumb typing on a cell-phone, and performance on a phone recognition task at the end of the trial was assessed. Disrupting motor processing over the thumb representation 100 ms after the onset of the typing video impaired the ability to recognize the phone in the recognition test, whereas there was no such effect for TMS applied over the vertex and no TMS trials. Furthermore, this effect only manifested for videos observed from the first person perspective. In an additional control condition, there was no evidence for any effects of TMS to the thumb representation or vertex when observing and recognizing non-action related shape stimuli. Conclusion Overall, these data provide evidence that motor cortical processing during observation of object-directed actions from a first person perspective is causally linked to the formation of enduring representations of objects-of-action. PMID:24330638

  17. Non-equilibrium condensation process in holographic superconductor with nonlinear electrodynamics

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Yunqi; Gong, Yungui [School of Physics, Huazhong University of Science and Technology,Wuhan, Hubei 430074 (China); Wang, Bin [IFSA Collaborative Innovation Center, Department of Physics and Astronomy, Shanghai Jiao Tong University,Shanghai 200240 (China)

    2016-02-17

    We study the non-equilibrium condensation process in a holographic superconductor with nonlinear corrections to the U(1) gauge field. We start with an asymptotic Anti-de-Sitter(AdS) black hole against a complex scalar perturbation at the initial time, and solve the dynamics of the gravitational systems in the bulk. When the black hole temperature T is smaller than a critical value T{sub c}, the scalar perturbation grows exponentially till saturation, the final state of spacetime approaches to a hairy black hole. In the bulk theory, we find the clue of the influence of nonlinear corrections in the gauge filed on the process of the scalar field condensation. We show that the bulk dynamics in the non-equilibrium process is completely consistent with the observations on the boundary order parameter. Furthermore we examine the time evolution of horizons in the bulk non-equilibrium transformation process from the bald AdS black hole to the AdS hairy hole. Both the evolution of apparent and event horizons show that the original AdS black hole configuration requires more time to finish the transformation to become a hairy black hole if there is nonlinear correction to the electromagnetic field. We generalize our non-equilibrium discussions to the holographic entanglement entropy and find that the holographic entanglement entropy can give us further understanding of the influence of the nonlinearity in the gauge field on the scalar condensation.

  18. Perturbation and characterization of nonlinear processes. Progress report, November 15, 1984-November 14, 1985

    International Nuclear Information System (INIS)

    Swinney, H.L.; Swift, J.

    1985-01-01

    Methods of characterizing nonperiodic processes in nonlinear systems are being developed and tested on low dimensional mathematical models and applied to laboratory data for nonequilibrium systems, particularly the Belousov--Zhabotinskii (BZ) reaction. Methods developed for characterizing dynamical behavior are described first, followed by a discussion of the experimental work

  19. Scene matching based on non-linear pre-processing on reference image and sensed image

    Institute of Scientific and Technical Information of China (English)

    Zhong Sheng; Zhang Tianxu; Sang Nong

    2005-01-01

    To solve the heterogeneous image scene matching problem, a non-linear pre-processing method for the original images before intensity-based correlation is proposed. The result shows that the proper matching probability is raised greatly. Especially for the low S/N image pairs, the effect is more remarkable.

  20. Public involvement in the decision making process, Argentine experience

    International Nuclear Information System (INIS)

    Clein, D.

    1999-01-01

    In the frame of a young participative democracy the Comision Nacional de Energia Atomica (C.N.E.A.), technical and legal responsible for radioactive waste management, is developing a plan for the close out of tailings facilities from past mining and milling operations and the environmental restoration of nine different sites in six provinces all over the country. In the first site, Malargue Facility, different activities have been developed promoting public involvement in the decision making process. The lessons learned and the experience acquired have given the background for the systematization of public consultation in the ongoing and future stages of the plan. Malargue's experience in this field will be analyzed stressing on different aspects considered of importance for the design of a communicational strategy adapted to the characteristics of a society without experience in this field. The influence of public concern on conservative bias of technical decisions will be evaluated. (author)

  1. Fault Detection for Nonlinear Process With Deterministic Disturbances: A Just-In-Time Learning Based Data Driven Method.

    Science.gov (United States)

    Yin, Shen; Gao, Huijun; Qiu, Jianbin; Kaynak, Okyay

    2017-11-01

    Data-driven fault detection plays an important role in industrial systems due to its applicability in case of unknown physical models. In fault detection, disturbances must be taken into account as an inherent characteristic of processes. Nevertheless, fault detection for nonlinear processes with deterministic disturbances still receive little attention, especially in data-driven field. To solve this problem, a just-in-time learning-based data-driven (JITL-DD) fault detection method for nonlinear processes with deterministic disturbances is proposed in this paper. JITL-DD employs JITL scheme for process description with local model structures to cope with processes dynamics and nonlinearity. The proposed method provides a data-driven fault detection solution for nonlinear processes with deterministic disturbances, and owns inherent online adaptation and high accuracy of fault detection. Two nonlinear systems, i.e., a numerical example and a sewage treatment process benchmark, are employed to show the effectiveness of the proposed method.

  2. NONLINEAR REFLECTION PROCESS OF LINEARLY POLARIZED, BROADBAND ALFVÉN WAVES IN THE FAST SOLAR WIND

    Energy Technology Data Exchange (ETDEWEB)

    Shoda, M.; Yokoyama, T., E-mail: shoda@eps.s.u-tokyo.ac.jp [Department of Earth and Planetary Science, The University of Tokyo, Bunkyo-ku, Tokyo 113-0033 (Japan)

    2016-04-01

    Using one-dimensional numerical simulations, we study the elementary process of Alfvén wave reflection in a uniform medium, including nonlinear effects. In the linear regime, Alfvén wave reflection is triggered only by the inhomogeneity of the medium, whereas in the nonlinear regime, it can occur via nonlinear wave–wave interactions. Such nonlinear reflection (backscattering) is typified by decay instability. In most studies of decay instabilities, the initial condition has been a circularly polarized Alfvén wave. In this study we consider a linearly polarized Alfvén wave, which drives density fluctuations by its magnetic pressure force. For generality, we also assume a broadband wave with a red-noise spectrum. In the data analysis, we decompose the fluctuations into characteristic variables using local eigenvectors, thus revealing the behaviors of the individual modes. Different from the circular-polarization case, we find that the wave steepening produces a new energy channel from the parent Alfvén wave to the backscattered one. Such nonlinear reflection explains the observed increasing energy ratio of the sunward to the anti-sunward Alfvénic fluctuations in the solar wind with distance against the dynamical alignment effect.

  3. Nonlinear Pulse Shaping in Fibres for Pulse Generation and Optical Processing

    Directory of Open Access Journals (Sweden)

    Sonia Boscolo

    2012-01-01

    Full Text Available The development of new all-optical technologies for data processing and signal manipulation is a field of growing importance with a strong potential for numerous applications in diverse areas of modern science. Nonlinear phenomena occurring in optical fibres have many attractive features and great, but not yet fully explored, potential in signal processing. Here, we review recent progress on the use of fibre nonlinearities for the generation and shaping of optical pulses and on the applications of advanced pulse shapes in all-optical signal processing. Amongst other topics, we will discuss ultrahigh repetition rate pulse sources, the generation of parabolic shaped pulses in active and passive fibres, the generation of pulses with triangular temporal profiles, and coherent supercontinuum sources. The signal processing applications will span optical regeneration, linear distortion compensation, optical decision at the receiver in optical communication systems, spectral and temporal signal doubling, and frequency conversion.

  4. Suppression of two-photon resonantly enhanced nonlinear processes in extended media

    International Nuclear Information System (INIS)

    Garrett, W.R.; Moore, M.A.; Payne, M.G.; Wunderlich, R.K.

    1988-11-01

    On the basis of combined experimental and theoretical studies of nonlinear processes associated with two-photon excitations near 3d and 4d states in Na, we show how resonantly enhanced stimulated hyper-Raman emission, parametric four-wave mixing processes and total resonant two-photon absorption can become severely suppressed through the actions of internally generated fields on the total atomic response in extended media. 7 refs., 3 figs

  5. Experimental photonic generation of chirped pulses using nonlinear dispersion-based incoherent processing.

    Science.gov (United States)

    Rius, Manuel; Bolea, Mario; Mora, José; Ortega, Beatriz; Capmany, José

    2015-05-18

    We experimentally demonstrate, for the first time, a chirped microwave pulses generator based on the processing of an incoherent optical signal by means of a nonlinear dispersive element. Different capabilities have been demonstrated such as the control of the time-bandwidth product and the frequency tuning increasing the flexibility of the generated waveform compared to coherent techniques. Moreover, the use of differential detection improves considerably the limitation over the signal-to-noise ratio related to incoherent processing.

  6. Nonlinearities in Drug Release Process from Polymeric Microparticles: Long-Time-Scale Behaviour

    Directory of Open Access Journals (Sweden)

    Elena Simona Bacaita

    2012-01-01

    Full Text Available A theoretical model of the drug release process from polymeric microparticles (a particular type of polymer matrix, through dispersive fractal approximation of motion, is built. As a result, the drug release process takes place through cnoidal oscillations modes of a normalized concentration field. This indicates that, in the case of long-time-scale evolutions, the drug particles assemble in a lattice of nonlinear oscillators occur macroscopically, through variations of drug concentration. The model is validated by experimental results.

  7. Brain signal variability as a window into the bidirectionality between music and language processing: moving from a linear to a nonlinear model.

    Science.gov (United States)

    Hutka, Stefanie; Bidelman, Gavin M; Moreno, Sylvain

    2013-12-30

    There is convincing empirical evidence for bidirectional transfer between music and language, such that experience in either domain can improve mental processes required by the other. This music-language relationship has been studied using linear models (e.g., comparing mean neural activity) that conceptualize brain activity as a static entity. The linear approach limits how we can understand the brain's processing of music and language because the brain is a nonlinear system. Furthermore, there is evidence that the networks supporting music and language processing interact in a nonlinear manner. We therefore posit that the neural processing and transfer between the domains of language and music are best viewed through the lens of a nonlinear framework. Nonlinear analysis of neurophysiological activity may yield new insight into the commonalities, differences, and bidirectionality between these two cognitive domains not measurable in the local output of a cortical patch. We thus propose a novel application of brain signal variability (BSV) analysis, based on mutual information and signal entropy, to better understand the bidirectionality of music-to-language transfer in the context of a nonlinear framework. This approach will extend current methods by offering a nuanced, network-level understanding of the brain complexity involved in music-language transfer.

  8. Brain signal variability as a window into the bidirectionality between music and language processing: Moving from a linear to a nonlinear model

    Directory of Open Access Journals (Sweden)

    Stefanie Andrea Hutka

    2013-12-01

    Full Text Available There is convincing empirical evidence for bidirectional transfer between music and language, such that experience in either domain can improve mental processes required by the other. This music-language relationship has been studied using linear models (e.g., comparing mean neural activity that conceptualize brain activity as a static entity. The linear approach limits how we can understand the brain’s processing of music and language because the brain is a nonlinear system. Furthermore, there is evidence that the networks supporting music and language processing interact in a nonlinear manner. We therefore posit that the neural processing and transfer between the domains of language and music are best viewed through the lens of a nonlinear framework. Nonlinear analysis of neurophysiological activity may yield new insight into the commonalities, differences, and bidirectionality between these two cognitive domains not measurable in the local output of a cortical patch. We thus propose a novel application of brain signal variability (BSV analysis, based on mutual information and signal entropy, to better understand the bidirectionality of music-to-language transfer in the context of a nonlinear framework. This approach will extend current methods by offering a nuanced, network-level understanding of the brain complexity involved in music-language transfer.

  9. Some applications of nonlinear diffusion to processing of dynamic evolution images

    International Nuclear Information System (INIS)

    Goltsov, Alexey N.; Nikishov, Sergey A.

    1997-01-01

    Model nonlinear diffusion equation with the most simple Landau-Ginzburg free energy functional was applied to locate boundaries between meaningful regions of low-level images. The method is oriented to processing images of objects that are a result of dynamic evolution: images of different organs and tissues obtained by radiography and NMR methods, electron microscope images of morphogenesis fields, etc. In the methods developed by us, parameters of the nonlinear diffusion model are chosen on the basis of the preliminary treatment of the images. The parameters of the Landau-Ginzburg free energy functional are extracted from the structure factor of the images. Owing to such a choice of the model parameters, the image to be processed is located in the vicinity of the steady-state of the diffusion equation. The suggested method allows one to separate distinct structures having specific space characteristics from the whole image. The method was applied to processing X-ray images of the lung

  10. Effects of noise, nonlinear processing, and linear filtering on perceived music quality.

    Science.gov (United States)

    Arehart, Kathryn H; Kates, James M; Anderson, Melinda C

    2011-03-01

    The purpose of this study was to determine the relative impact of different forms of hearing aid signal processing on quality ratings of music. Music quality was assessed using a rating scale for three types of music: orchestral classical music, jazz instrumental, and a female vocalist. The music stimuli were subjected to a wide range of simulated hearing aid processing conditions including, (1) noise and nonlinear processing, (2) linear filtering, and (3) combinations of noise, nonlinear, and linear filtering. Quality ratings were measured in a group of 19 listeners with normal hearing and a group of 15 listeners with sensorineural hearing impairment. Quality ratings in both groups were generally comparable, were reliable across test sessions, were impacted more by noise and nonlinear signal processing than by linear filtering, and were significantly affected by the genre of music. The average quality ratings for music were reasonably well predicted by the hearing aid speech quality index (HASQI), but additional work is needed to optimize the index to the wide range of music genres and processing conditions included in this study.

  11. Parametric Phase-sensitive and Phase-insensitive All-optical Signal Processing on Multiple Nonlinear Platforms - Invited talk

    DEFF Research Database (Denmark)

    Peucheret, Christophe; Da Ros, Francesco; Vukovic, Dragana

    Parametric processes in materials presenting a second- or third-order nonlinearity have been widely used to demonstrate a wide range of all-optical signal processing functionalities, including amplication, wavelength conversion, regeneration, sampling, switching, modulation format conver- sion, o...

  12. Observations of linear and nonlinear processes in the foreshock wave evolution

    Directory of Open Access Journals (Sweden)

    Y. Narita

    2007-07-01

    Full Text Available Waves in the foreshock region are studied on the basis of a hypothesis that the linear process first excites the waves and further wave-wave nonlinearities distribute scatter the energy of the primary waves into a number of daughter waves. To examine this wave evolution scenario, the dispersion relations, the wave number spectra of the magnetic field energy, and the dimensionless cross helicity are determined from the observations made by the four Cluster spacecraft. The results confirm that the linear process is the ion/ion right-hand resonant instability, but the wave-wave interactions are not clearly identified. We discuss various reasons why the test for the wave-wave nonlinearities fails, and conclude that the higher order statistics would provide a direct evidence for the wave coupling phenomena.

  13. Green functions and Langevin equations for nonlinear diffusion equations: A comment on ‘Markov processes, Hurst exponents, and nonlinear diffusion equations’ by Bassler et al.

    Science.gov (United States)

    Frank, T. D.

    2008-02-01

    We discuss two central claims made in the study by Bassler et al. [K.E. Bassler, G.H. Gunaratne, J.L. McCauley, Physica A 369 (2006) 343]. Bassler et al. claimed that Green functions and Langevin equations cannot be defined for nonlinear diffusion equations. In addition, they claimed that nonlinear diffusion equations are linear partial differential equations disguised as nonlinear ones. We review bottom-up and top-down approaches that have been used in the literature to derive Green functions for nonlinear diffusion equations and, in doing so, show that the first claim needs to be revised. We show that the second claim as well needs to be revised. To this end, we point out similarities and differences between non-autonomous linear Fokker-Planck equations and autonomous nonlinear Fokker-Planck equations. In this context, we raise the question whether Bassler et al.’s approach to financial markets is physically plausible because it necessitates the introduction of external traders and causes. Such external entities can easily be eliminated when taking self-organization principles and concepts of nonextensive thermostatistics into account and modeling financial processes by means of nonlinear Fokker-Planck equations.

  14. EGS Richardson AGU Chapman NVAG3 Conference: Nonlinear Variability in Geophysics: scaling and multifractal processes

    OpenAIRE

    D. Schertzer; S. Lovejoy; S. Lovejoy

    1994-01-01

    1. The conference The third conference on "Nonlinear VAriability in Geophysics: scaling and multifractal processes" (NVAG 3) was held in Cargese, Corsica, Sept. 10-17, 1993. NVAG3 was joint American Geophysical Union Chapman and European Geophysical Society Richardson Memorial conference, the first specialist conference jointly sponsored by the two organizations. It followed NVAG1 (Montreal, Aug. 1986), NVAG2 (Paris, June 1988; Schertzer and Lovejoy, 1991), five consecutive annual ...

  15. EGS Richardson AGU Chapman NVAG3 Conference: Nonlinear Variability in Geophysics: scaling and multifractal processes

    OpenAIRE

    Schertzer , D; Lovejoy , S.

    1994-01-01

    International audience; 1. The conference The third conference on "Nonlinear VAriability in Geophysics: scaling and multifractal processes" (NVAG 3) was held in Cargese, Corsica, Sept. 10-17, 1993. NVAG3 was joint American Geophysical Union Chapman and European Geophysical Society Richardson Memorial conference, the first specialist conference jointly sponsored by the two organizations. It followed NVAG1 (Montreal, Aug. 1986), NVAG2 (Paris, June 1988; Schertzer and Lovejoy, 1991), five conse...

  16. Predicting seizures in untreated temporal lobe epilepsy using point-process nonlinear models of heartbeat dynamics.

    Science.gov (United States)

    Valenza, G; Romigi, A; Citi, L; Placidi, F; Izzi, F; Albanese, M; Scilingo, E P; Marciani, M G; Duggento, A; Guerrisi, M; Toschi, N; Barbieri, R

    2016-08-01

    Symptoms of temporal lobe epilepsy (TLE) are frequently associated with autonomic dysregulation, whose underlying biological processes are thought to strongly contribute to sudden unexpected death in epilepsy (SUDEP). While abnormal cardiovascular patterns commonly occur during ictal events, putative patterns of autonomic cardiac effects during pre-ictal (PRE) periods (i.e. periods preceding seizures) are still unknown. In this study, we investigated TLE-related heart rate variability (HRV) through instantaneous, nonlinear estimates of cardiovascular oscillations during inter-ictal (INT) and PRE periods. ECG recordings from 12 patients with TLE were processed to extract standard HRV indices, as well as indices of instantaneous HRV complexity (dominant Lyapunov exponent and entropy) and higher-order statistics (bispectra) obtained through definition of inhomogeneous point-process nonlinear models, employing Volterra-Laguerre expansions of linear, quadratic, and cubic kernels. Experimental results demonstrate that the best INT vs. PRE classification performance (balanced accuracy: 73.91%) was achieved only when retaining the time-varying, nonlinear, and non-stationary structure of heartbeat dynamical features. The proposed approach opens novel important avenues in predicting ictal events using information gathered from cardiovascular signals exclusively.

  17. Sub-wavelength patterning of organic monolayers via nonlinear processing with continuous-wave lasers

    Energy Technology Data Exchange (ETDEWEB)

    Mathieu, Mareike; Hartmann, Nils, E-mail: nils.hartmann@uni-due.de [Fakultaet fuer Chemie, Universitaet Duisburg-Essen, 45117 Essen (Germany); CeNIDE-Center for Nanointegration Duisburg-Essen, 47048 Duisburg (Germany); NETZ-NanoEnergieTechnikZentrum, 47048 Duisburg (Germany)

    2010-12-15

    In recent years, nonlinear processing with continuous-wave lasers has been demonstrated to be a facile means of rapid nanopatterning of organic monolayers down to the sub-100 nm range. In this study, we report on laser patterning of thiol-based organic monolayers with sub-wavelength resolution. Au-coated silicon substrates are functionalized with 1-hexadecanethiol. Irradiation with a focused beam of an Ar{sup +} laser operating at {lambda}=514 nm allows one to locally remove the monolayer. Subsequently, the patterns are transferred into the Au film via selective etching in a ferri-/ferrocyanide solution. Despite a 1/e{sup 2} spot diameter of about 2.8 {mu}m, structures with lateral dimensions down to 250 nm are fabricated. The underlying nonlinear dependence of the patterning process on laser intensity is traced back to the interplay between the laser-induced transient local temperature rise and the thermally activated desorption of the thiol molecules. A simple thermokinetic analysis of the data allows us to determine the effective kinetic parameters. These results complement our previous work on photothermal laser patterning of ultrathin organic coatings, such as silane-based organic monolayers, organo/silicon interfaces and supported membranes. A general introduction to nonlinear laser processing of organic monolayers is presented.

  18. The Characterization of Cognitive Processes Involved in Chemical Kinetics Using a Blended Processing Framework

    Science.gov (United States)

    Bain, Kinsey; Rodriguez, Jon-Marc G.; Moon, Alena; Towns, Marcy H.

    2018-01-01

    Chemical kinetics is a highly quantitative content area that involves the use of multiple mathematical representations to model processes and is a context that is under-investigated in the literature. This qualitative study explored undergraduate student integration of chemistry and mathematics during problem solving in the context of chemical…

  19. Data-driven design of fault diagnosis systems nonlinear multimode processes

    CERN Document Server

    Haghani Abandan Sari, Adel

    2014-01-01

    In many industrial applications early detection and diagnosis of abnormal behavior of the plant is of great importance. During the last decades, the complexity of process plants has been drastically increased, which imposes great challenges in development of model-based monitoring approaches and it sometimes becomes unrealistic for modern large-scale processes. The main objective of Adel Haghani Abandan Sari is to study efficient fault diagnosis techniques for complex industrial systems using process historical data and considering the nonlinear behavior of the process. To this end, different methods are presented to solve the fault diagnosis problem based on the overall behavior of the process and its dynamics. Moreover, a novel technique is proposed for fault isolation and determination of the root-cause of the faults in the system, based on the fault impacts on the process measurements. Contents Process monitoring Fault diagnosis and fault-tolerant control Data-driven approaches and decision making Target...

  20. Ultrafast nonlinear optical processes in metal-dielectric nanocomposites and nanostructures

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Kwang-Hyon

    2012-04-13

    This work reports results of a theoretical study of nonlinear optical processes in metal-dielectric nanocomposites used for the increase of the nonlinear coefficients and for plasmonic field enhancement. The main results include the study of the transient saturable nonlinearity in dielectric composites doped with metal nanoparticles, its physical mechanism as well its applications in nonlinear optics. For the study of the transient response, a time-depending equation for the dielectric function of the nanocomposite using the semi-classical two-temperature model is derived. By using this approach, we study the transient nonlinear characteristics of these materials in comparison with preceding experimental measurements. The results show that these materials behave as efficient saturable absorbers for passive mode-locking of lasers in the spectral range from the visible to near IR. We present results for the modelocked dynamics in short-wavelength solid-state and semiconductor disk lasers; in this spectral range other efficient saturable absorbers do not exist. We suggest a new mechanism for the realization of slow light phenomenon by using glasses doped with metal nanoparticles in a pump-probe regime near the plasmonic resonance. Furthermore, we study femtosecond plasmon generation by mode-locked surface plasmon polariton lasers with Bragg reflectors and metal-gain-absorber layered structures. In the final part of the thesis, we present results for high-order harmonic generation near a metallic fractal rough surface. The results show a possible reduction of the pump intensities by three orders of magnitudes and two orders of magnitudes higher efficiency compared with preceding experimental results by using bow-tie nanostructures.

  1. Drowning unconformities: Palaeoenvironmental significance and involvement of global processes

    Science.gov (United States)

    Godet, Alexis

    2013-07-01

    Drowning unconformities are stratigraphic key surfaces in the history of carbonate platforms. They mostly consist in the deposition of deep marine facies on top of shallow marine limestones. Although large-scale depositional geometries mimic lowstand systems track architecture, these sedimentary turnovers are developed in relation with major sea level rise, inducing an increase in the rate of creation of accommodation space that outpaces the capacity of carbonate to keep up. This so-called paradox of carbonate platform drowning implies that parameters other than purely eustatic fluctuations are involved in the demise of shallow marine ecosystems. Worldwide and at different times during Earth history, in-depth studies of drowning unconformities revealed that changes in nutrient input, clastic delivery, temperature, or a combination of them may be responsible for a decrease in light penetration in the water column and the progressive suffocation and poisoning of photosynthetic carbonate producers. The examination of such case examples from various stratigraphic intervals and palaeogeographical settings thus helps in identifying and hierarchizing potential triggering mechanisms for drowning unconformities. This is complemented by new data from Early Cretaceous successions from the Helvetic Alps. During this time period, the Helvetic carbonate platform developed along the northern Tethyan margin using both photozoan and heterozoan communities. Phases of healthy production were interrupted by several drowning episodes. The latter are marked in the sedimentary record by condensation and associated phosphogenesis and glauconitisation. From the earliest Valanginian to the early to late Barremian, three drowning unconformities reflect the intermittent installation of a more humid climate and subsequent enhanced trophic conditions, which first induced a switch from photozoan to heterozoan communities and then to long-lasting drowning phases. The latter encompass several sea

  2. Parametric amplification and cascaded-nonlinearity processes in common atomic system.

    Science.gov (United States)

    Zheng, Huaibin; Zhang, Xun; Zhang, Zhaoyang; Tian, Yaling; Chen, Haixia; Li, Changbiao; Zhang, Yanpeng

    2013-01-01

    For the first time, we study the parametric amplification process of multi-wave mixing (PA-MWM) signal and cascaded-nonlinearity process (CNP) in sodium vapors both theoretically and experimentally, based on a conventional phase-conjugate MWM and a self-diffraction four-wave mixing (SD-FWM) processes, which are pumped by laser or amplified spontaneous emission (ASE), respectively. For laser pumping case, SD-FWM process serves as a quantum linear amplifier (a CNP) out (inside) of the resonant absorption region. While for ASE case, only the CNP occurs and the output linewidth is much narrower than that of the MWM signal due to the second selected effect of its electromagnetically induced transparency window. In addition, the phase-sensitive amplifying process seeded by two MWM processes is discussed for the first time. Theoretical fittings agree well with the experiment. The investigations have important potential applications in quantum communication.

  3. Photo-physics of third-order nonlinear optical processes in organic dyes

    International Nuclear Information System (INIS)

    Delysse, Stephane

    1997-01-01

    We study some aspects of the nonlinear picosecond photo-physics in organic dyes using Kerr ellipsometry. The aim is to establish link between the photo-physics and nonlinear optics in these compounds. First, we study coherent processes directly linked to the third-order susceptibility. Thus, we measure two-photon absorption spectra of large internal charge transfer dyes. We take into account all coupling between three electronic states which can interfere to explain the particular response of some stilbene dyes. On the second hand, we expose a more photophysical approach to determine the S 1 → S n transition energies and moments using the measurement of excited state absorption cross sections. These results allow the prediction of the susceptibilities relevant to alternative nonlinear optical methods. Nevertheless, the stationary approach hides the complex relaxation processes which can take place in organic dyes. As an illustration, we study the formation and disappearance of a TICT (Twisted intramolecular charge transfer) in a pyrylium salt in solvents of increasing viscosity. (author) [fr

  4. From point process observations to collective neural dynamics: Nonlinear Hawkes process GLMs, low-dimensional dynamics and coarse graining.

    Science.gov (United States)

    Truccolo, Wilson

    2016-11-01

    This review presents a perspective on capturing collective dynamics in recorded neuronal ensembles based on multivariate point process models, inference of low-dimensional dynamics and coarse graining of spatiotemporal measurements. A general probabilistic framework for continuous time point processes reviewed, with an emphasis on multivariate nonlinear Hawkes processes with exogenous inputs. A point process generalized linear model (PP-GLM) framework for the estimation of discrete time multivariate nonlinear Hawkes processes is described. The approach is illustrated with the modeling of collective dynamics in neocortical neuronal ensembles recorded in human and non-human primates, and prediction of single-neuron spiking. A complementary approach to capture collective dynamics based on low-dimensional dynamics ("order parameters") inferred via latent state-space models with point process observations is presented. The approach is illustrated by inferring and decoding low-dimensional dynamics in primate motor cortex during naturalistic reach and grasp movements. Finally, we briefly review hypothesis tests based on conditional inference and spatiotemporal coarse graining for assessing collective dynamics in recorded neuronal ensembles. Published by Elsevier Ltd.

  5. Study of a multivariable nonlinear process by the phase space method

    International Nuclear Information System (INIS)

    Tomei, Alain

    1969-02-01

    This paper concerns the study of the properties of a multivariate nonlinear process using the phase space method. Based on the example of the Rapsodie reactor, a fast sodium reactor, the authors have established the simplified differential equations with the analogical study of partial differential equations (in order to replace them with ordinary differential equations), a mathematical study of dynamic properties and stability of the simplified model by the phase space method, and the verification of the model properties using an analog calculator. The reactor, with all its thermal circuits, has been considered as a nonlinear system with two inputs and one output (reactor power). The great stability of a fast reactor such as Rapsodie, in the normal operating conditions, has been verified. The same method could be applied to any other type of reactor

  6. Nonlinear dynamics of three-magnon process driven by ferromagnetic resonance in yttrium iron garnet

    Energy Technology Data Exchange (ETDEWEB)

    Cunha, R. O. [Departamento de Física, Universidade Federal de Pernambuco, 50670-901 Recife, PE (Brazil); Centro Interdisciplinar de Ciências da Natureza, Universidade Federal da Integração Latino-Americana, 85867-970 Foz do Iguaçu, PR (Brazil); Holanda, J.; Azevedo, A.; Rezende, S. M., E-mail: rezende@df.ufpe.br [Departamento de Física, Universidade Federal de Pernambuco, 50670-901 Recife, PE (Brazil); Vilela-Leão, L. H. [Departamento de Física, Universidade Federal de Pernambuco, 50670-901 Recife, PE (Brazil); Centro Acadêmico do Agreste, Universidade Federal de Pernambuco, 55002-970 Caruaru, PE (Brazil); Rodríguez-Suárez, R. L. [Facultad de Física, Pontificia Universidad Católica de Chile, Casilla 306, Santiago (Chile)

    2015-05-11

    We report an investigation of the dynamics of the three-magnon splitting process associated with the ferromagnetic resonance (FMR) in films of the insulating ferrimagnet yttrium iron garnet (YIG). The experiments are performed with a 6 μm thick YIG film close to a microstrip line fed by a microwave generator operating in the 2–6 GHz range. The magnetization precession is driven by the microwave rf magnetic field perpendicular to the static magnetic field, and its dynamics is observed by monitoring the amplitude of the FMR absorption peak. The time evolution of the amplitude reveals that if the frequency is lowered below a critical value of 3.3 GHz, the FMR mode pumps two magnons with opposite wave vectors that react back on the FMR, resulting in a nonlinear dynamics of the magnetization. The results are explained by a model with coupled nonlinear equations describing the time evolution of the magnon modes.

  7. Linear and Nonlinear Impairment Compensation in Coherent Optical Transmission with Digital Signal Processing

    DEFF Research Database (Denmark)

    Porto da Silva, Edson

    Digital signal processing (DSP) has become one of the main enabling technologies for the physical layer of coherent optical communication networks. The DSP subsystems are used to implement several functionalities in the digital domain, from synchronization to channel equalization. Flexibility...... nonlinearity compensation, (II) spectral shaping, and (III) adaptive equalization. For (I), original contributions are presented to the study of the nonlinearity compensation (NLC) with digital backpropagation (DBP). Numerical and experimental performance investigations are shown for different application...... scenarios. Concerning (II), it is demonstrated how optical and electrical (digital) pulse shaping can be allied to improve the spectral confinement of a particular class of optical time-division multiplexing (OTDM) signals that can be used as a building block for fast signaling single-carrier transceivers...

  8. Mammalian Cell Culture Process for Monoclonal Antibody Production: Nonlinear Modelling and Parameter Estimation

    Directory of Open Access Journals (Sweden)

    Dan Selişteanu

    2015-01-01

    Full Text Available Monoclonal antibodies (mAbs are at present one of the fastest growing products of pharmaceutical industry, with widespread applications in biochemistry, biology, and medicine. The operation of mAbs production processes is predominantly based on empirical knowledge, the improvements being achieved by using trial-and-error experiments and precedent practices. The nonlinearity of these processes and the absence of suitable instrumentation require an enhanced modelling effort and modern kinetic parameter estimation strategies. The present work is dedicated to nonlinear dynamic modelling and parameter estimation for a mammalian cell culture process used for mAb production. By using a dynamical model of such kind of processes, an optimization-based technique for estimation of kinetic parameters in the model of mammalian cell culture process is developed. The estimation is achieved as a result of minimizing an error function by a particle swarm optimization (PSO algorithm. The proposed estimation approach is analyzed in this work by using a particular model of mammalian cell culture, as a case study, but is generic for this class of bioprocesses. The presented case study shows that the proposed parameter estimation technique provides a more accurate simulation of the experimentally observed process behaviour than reported in previous studies.

  9. Performance of Globally Linearized Controller and Two Region Fuzzy Logic Controller on a Nonlinear Process

    Directory of Open Access Journals (Sweden)

    N. Jaya

    2008-10-01

    Full Text Available In this work, a design and implementation of a Conventional PI controller, single region fuzzy logic controller, two region fuzzy logic controller and Globally Linearized Controller (GLC for a two capacity interacting nonlinear process is carried out. The performance of this process using single region FLC, two region FLC and GLC are compared with the performance of conventional PI controller about an operating point of 50 %. It has been observed that GLC and two region FLC provides better performance. Further, this procedure is also validated by real time experimentation using dSPACE.

  10. Interactive methods to involve users into workspace design process

    DEFF Research Database (Denmark)

    Souza da Conceição, Carolina; Broberg, Ole; Banke, Palle

    2013-01-01

    This paper addresses the question of whether the use of a combination of interactive methods involving workers can lead to a useful input to the (re)design of their workspace. The workbook and the layout design game methods were tested, and a comparison between their use and the ergonomic analysi...

  11. Parental Involvement and Children's School Achievement: Evidence for Mediating Processes

    Science.gov (United States)

    Rogers, Maria A.; Theule, Jennifer; Ryan, Bruce A.; Adams, Gerald R.; Keating, Leo

    2009-01-01

    This study used path analytic techniques and an ecological framework to examine the association between children's perceptions of their parents' educational involvement, children's personal characteristics, and their school achievement. Fathers' academic pressure was predictive of lower achievement, whereas mothers' encouragement and support…

  12. Nonlinear modeling and dynamic analysis of hydro-turbine governing system in the process of load rejection transient

    International Nuclear Information System (INIS)

    Zhang, Hao; Chen, Diyi; Xu, Beibei; Wang, Feifei

    2015-01-01

    Graphical abstract: Nonlinear dynamic transfer coefficients are introduced to the hydro-turbine governing system. In the process of load reject ion transient, the nonlinear dynamical behaviors of the system are studied in detail. - Highlights: • A novel mathematical model of a hydro-turbine governing system is established. • The process of load rejection transient is considered. • Nonlinear dynamic transfer coefficients are introduced to the system. • The bifurcation diagram with the variable t has better engineering significance. • The nonlinear dynamical behaviors of the system are studied in detail. - Abstract: This article pays attention to the mathematical modeling of a hydro-turbine governing system in the process of load rejection transient. As a pioneer work, the nonlinear dynamic transfer coefficients are introduced in a penstock system. Considering a generator system, a turbine system and a governor system, we present a novel nonlinear dynamical model of a hydro-turbine governing system. Fortunately, for the unchanged of PID parameters, we acquire the stable regions of the governing system in the process of load rejection transient by numerical simulations. Moreover, the nonlinear dynamic behaviors of the governing system are illustrated by bifurcation diagrams, Poincare maps, time waveforms and phase orbits. More importantly, these methods and analytic results will present theoretical groundwork for allowing a hydropower station in the process of load rejection transient

  13. When high working memory capacity is and is not beneficial for predicting nonlinear processes.

    Science.gov (United States)

    Fischer, Helen; Holt, Daniel V

    2017-04-01

    Predicting the development of dynamic processes is vital in many areas of life. Previous findings are inconclusive as to whether higher working memory capacity (WMC) is always associated with using more accurate prediction strategies, or whether higher WMC can also be associated with using overly complex strategies that do not improve accuracy. In this study, participants predicted a range of systematically varied nonlinear processes based on exponential functions where prediction accuracy could or could not be enhanced using well-calibrated rules. Results indicate that higher WMC participants seem to rely more on well-calibrated strategies, leading to more accurate predictions for processes with highly nonlinear trajectories in the prediction region. Predictions of lower WMC participants, in contrast, point toward an increased use of simple exemplar-based prediction strategies, which perform just as well as more complex strategies when the prediction region is approximately linear. These results imply that with respect to predicting dynamic processes, working memory capacity limits are not generally a strength or a weakness, but that this depends on the process to be predicted.

  14. Across frequency processes involved in auditory detection of coloration

    DEFF Research Database (Denmark)

    Buchholz, Jörg; Kerketsos, P

    2008-01-01

    filterbank was designed to approximate auditory filter-shapes measured by Oxenham and Shera [JARO, 2003, 541-554], derived from forward masking data. The results of the present study demonstrate that a “purely” spectrum-based model approach can successfully describe auditory coloration detection even at high......When an early wall reflection is added to a direct sound, a spectral modulation is introduced to the signal's power spectrum. This spectral modulation typically produces an auditory sensation of coloration or pitch. Throughout this study, auditory spectral-integration effects involved in coloration...... detection are investigated. Coloration detection thresholds were therefore measured as a function of reflection delay and stimulus bandwidth. In order to investigate the involved auditory mechanisms, an auditory model was employed that was conceptually similar to the peripheral weighting model [Yost, JASA...

  15. State and parameter estimation based on a nonlinear filter applied to an industrial process control of ethanol production

    Directory of Open Access Journals (Sweden)

    Meleiro L.A.C.

    2000-01-01

    Full Text Available Most advanced computer-aided control applications rely on good dynamics process models. The performance of the control system depends on the accuracy of the model used. Typically, such models are developed by conducting off-line identification experiments on the process. These experiments for identification often result in input-output data with small output signal-to-noise ratio, and using these data results in inaccurate model parameter estimates [1]. In this work, a multivariable adaptive self-tuning controller (STC was developed for a biotechnological process application. Due to the difficulties involving the measurements or the excessive amount of variables normally found in industrial process, it is proposed to develop "soft-sensors" which are based fundamentally on artificial neural networks (ANN. A second approach proposed was set in hybrid models, results of the association of deterministic models (which incorporates the available prior knowledge about the process being modeled with artificial neural networks. In this case, kinetic parameters - which are very hard to be accurately determined in real time industrial plants operation - were obtained using ANN predictions. These methods are especially suitable for the identification of time-varying and nonlinear models. This advanced control strategy was applied to a fermentation process to produce ethyl alcohol (ethanol in industrial scale. The reaction rate considered for substratum consumption, cells and ethanol productions are validated with industrial data for typical operating conditions. The results obtained show that the proposed procedure in this work has a great potential for application.

  16. Research Education: Perspectives and subjective processes involved in educational research

    Directory of Open Access Journals (Sweden)

    Harm H. Tillema

    2009-10-01

    Full Text Available Educational research acknowledges that researcher’s beliefs and training play a role in framing the outcomes of any study. Research not only consists of defining objectives and following certain methods (search but also of making decisions over the steps taking during the inquiry process (research.Establishing a conceptual framework to guide actions on the subjective processes in research is then crucial to control them. With that purpose in mind we offer researchers and Teacher Educators a heuristic tool to be conscious on the risks that can be taken when immersed in research interpretative process. This instrument could be utilised in PhD programs, masters and research projects.

  17. Nonlinear dynamics of regenerative cutting processes-Comparison of two models

    International Nuclear Information System (INIS)

    Wang, X.S.; Hu, J.; Gao, J.B.

    2006-01-01

    Understanding the nonlinear dynamics of cutting processes is essential for the improvement of machining technology. We study machine cutting processes by two different models, one has been recently introduced by Litak [Litak G. Chaotic vibrations in a regenerative cutting process. Chaos, Solitons and Fractals 2002;13:1531-5] and the other is the classic delay differential equation model. Although chaotic solutions have been found in both models, well known routes to chaos, such as period-doubling or quasi-periodic motion to chaos are not observed in either model. Careful analysis shows that the chaotic motion from the Litak's model has sharper spectral peaks, a smaller correlation dimension and a smaller value for the largest positive Lyapunov exponent. Implications to the control of chaos in cutting processes are discussed

  18. Definition of distance for nonlinear time series analysis of marked point process data

    Energy Technology Data Exchange (ETDEWEB)

    Iwayama, Koji, E-mail: koji@sat.t.u-tokyo.ac.jp [Research Institute for Food and Agriculture, Ryukoku Univeristy, 1-5 Yokotani, Seta Oe-cho, Otsu-Shi, Shiga 520-2194 (Japan); Hirata, Yoshito; Aihara, Kazuyuki [Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505 (Japan)

    2017-01-30

    Marked point process data are time series of discrete events accompanied with some values, such as economic trades, earthquakes, and lightnings. A distance for marked point process data allows us to apply nonlinear time series analysis to such data. We propose a distance for marked point process data which can be calculated much faster than the existing distance when the number of marks is small. Furthermore, under some assumptions, the Kullback–Leibler divergences between posterior distributions for neighbors defined by this distance are small. We performed some numerical simulations showing that analysis based on the proposed distance is effective. - Highlights: • A new distance for marked point process data is proposed. • The distance can be computed fast enough for a small number of marks. • The method to optimize parameter values of the distance is also proposed. • Numerical simulations indicate that the analysis based on the distance is effective.

  19. The Interaction between Personality, Social Network Position and Involvement in Innovation Process

    NARCIS (Netherlands)

    E. Dolgova (Evgenia); W. van Olffen (Woody); F.A.J. van den Bosch (Frans); H.W. Volberda (Henk)

    2010-01-01

    textabstractAbstract This dissertation proposal investigates how personality and individuals’ social network position affect individuals’ involvement into the innovation process. It posits that people would feel inclined to become involved into the different phases of the innovation process

  20. A novel joint-processing adaptive nonlinear equalizer using a modular recurrent neural network for chaotic communication systems.

    Science.gov (United States)

    Zhao, Haiquan; Zeng, Xiangping; Zhang, Jiashu; Liu, Yangguang; Wang, Xiaomin; Li, Tianrui

    2011-01-01

    To eliminate nonlinear channel distortion in chaotic communication systems, a novel joint-processing adaptive nonlinear equalizer based on a pipelined recurrent neural network (JPRNN) is proposed, using a modified real-time recurrent learning (RTRL) algorithm. Furthermore, an adaptive amplitude RTRL algorithm is adopted to overcome the deteriorating effect introduced by the nesting process. Computer simulations illustrate that the proposed equalizer outperforms the pipelined recurrent neural network (PRNN) and recurrent neural network (RNN) equalizers. Copyright © 2010 Elsevier Ltd. All rights reserved.

  1. Embedded algorithms within an FPGA-based system to process nonlinear time series data

    Science.gov (United States)

    Jones, Jonathan D.; Pei, Jin-Song; Tull, Monte P.

    2008-03-01

    This paper presents some preliminary results of an ongoing project. A pattern classification algorithm is being developed and embedded into a Field-Programmable Gate Array (FPGA) and microprocessor-based data processing core in this project. The goal is to enable and optimize the functionality of onboard data processing of nonlinear, nonstationary data for smart wireless sensing in structural health monitoring. Compared with traditional microprocessor-based systems, fast growing FPGA technology offers a more powerful, efficient, and flexible hardware platform including on-site (field-programmable) reconfiguration capability of hardware. An existing nonlinear identification algorithm is used as the baseline in this study. The implementation within a hardware-based system is presented in this paper, detailing the design requirements, validation, tradeoffs, optimization, and challenges in embedding this algorithm. An off-the-shelf high-level abstraction tool along with the Matlab/Simulink environment is utilized to program the FPGA, rather than coding the hardware description language (HDL) manually. The implementation is validated by comparing the simulation results with those from Matlab. In particular, the Hilbert Transform is embedded into the FPGA hardware and applied to the baseline algorithm as the centerpiece in processing nonlinear time histories and extracting instantaneous features of nonstationary dynamic data. The selection of proper numerical methods for the hardware execution of the selected identification algorithm and consideration of the fixed-point representation are elaborated. Other challenges include the issues of the timing in the hardware execution cycle of the design, resource consumption, approximation accuracy, and user flexibility of input data types limited by the simplicity of this preliminary design. Future work includes making an FPGA and microprocessor operate together to embed a further developed algorithm that yields better

  2. Processes involved in pion capture in hydrogen-containing molecules

    International Nuclear Information System (INIS)

    Horvath, D.

    1983-03-01

    A systematic analysis is presented of the possible elementary processes determining the fate of negative pions stopped in hydrogen-containing samples. Using a phenomenological description in comparison with the available experimental information on pion capture in hydrogen, it is shown that the formation and decay of pπ - atoms in compounds Zsub(m)Hsub(n) are determined mainly by the processes of Auger capture in a molecular orbit ZHπ - , transition from molecular to atomic orbit, transfer of pions to atoms Z in collisions pπ - +Z, and nuclear capture in collisions pπ - +H. The recent assumption of a considerable role of the processes of radiative atomic capture in bound hydrogen atoms, nuclear capture of pions by protons from the molecular state ZHπ - , or 'inner' transfer of the pion via tunnelling through the bond Z-H is not supported by the theory and contradicts the experimental data

  3. Processing and analysis techniques involving in-vessel material generation

    Science.gov (United States)

    Schabron, John F [Laramie, WY; Rovani, Jr., Joseph F.

    2012-09-25

    In at least one embodiment, the inventive technology relates to in-vessel generation of a material from a solution of interest as part of a processing and/or analysis operation. Preferred embodiments of the in-vessel material generation (e.g., in-vessel solid material generation) include precipitation; in certain embodiments, analysis and/or processing of the solution of interest may include dissolution of the material, perhaps as part of a successive dissolution protocol using solvents of increasing ability to dissolve. Applications include, but are by no means limited to estimation of a coking onset and solution (e.g., oil) fractionating.

  4. ADI splitting schemes for a fourth-order nonlinear partial differential equation from image processing

    KAUST Repository

    Calatroni, Luca

    2013-08-01

    We present directional operator splitting schemes for the numerical solution of a fourth-order, nonlinear partial differential evolution equation which arises in image processing. This equation constitutes the H -1-gradient flow of the total variation and represents a prototype of higher-order equations of similar type which are popular in imaging for denoising, deblurring and inpainting problems. The efficient numerical solution of this equation is very challenging due to the stiffness of most numerical schemes. We show that the combination of directional splitting schemes with implicit time-stepping provides a stable and computationally cheap numerical realisation of the equation.

  5. ADI splitting schemes for a fourth-order nonlinear partial differential equation from image processing

    KAUST Repository

    Calatroni, Luca; Dü ring, Bertram; Schö nlieb, Carola-Bibiane

    2013-01-01

    We present directional operator splitting schemes for the numerical solution of a fourth-order, nonlinear partial differential evolution equation which arises in image processing. This equation constitutes the H -1-gradient flow of the total variation and represents a prototype of higher-order equations of similar type which are popular in imaging for denoising, deblurring and inpainting problems. The efficient numerical solution of this equation is very challenging due to the stiffness of most numerical schemes. We show that the combination of directional splitting schemes with implicit time-stepping provides a stable and computationally cheap numerical realisation of the equation.

  6. Modeling human auditory evoked brainstem responses based on nonlinear cochlear processing

    DEFF Research Database (Denmark)

    Harte, James; Rønne, Filip Munch; Dau, Torsten

    2010-01-01

    . To generate AEPs recorded at remote locations, a convolution was made on an empirically obtained elementary unit waveform with the instantaneous discharge rate function for the corresponding AN unit. AEPs to click-trains, as well as to tone pulses at various frequencies, were both modelled and recorded...... at different stimulation levels and repetition rates. The observed nonlinearities in the recorded potential patterns, with respect to ABR wave V latencies and amplitudes, could be largely accounted for by level-dependent BM processing as well as effects of short-term neural adaptation. The present study...

  7. Intrinsic Nonlinearities and Layout Impacts of 100 V Integrated Power MOSFETs in Partial SOI Process

    DEFF Research Database (Denmark)

    Fan, Lin; Knott, Arnold; Jørgensen, Ivan Harald Holger

    Parasitic capacitances of power semiconductors are a part of the key design parameters of state-of-the-art very high frequency (VHF) power supplies. In this poster, four 100 V integrated power MOSFETs with different layout structures are designed, implemented, and analyzed in a 0.18 ȝm partial...... Silicon-on-Insulator (SOI) process with a die area 2.31 mm2.  A small-signal model of power MOSFETs is proposed to systematically analyze the nonlinear parasitic capacitances in different transistor states: off-state, sub-threshold region, and on-state in the linear region. 3D plots are used to summarize...

  8. Design optimization of single mixed refrigerant natural gas liquefaction process using the particle swarm paradigm with nonlinear constraints

    International Nuclear Information System (INIS)

    Khan, Mohd Shariq; Lee, Moonyong

    2013-01-01

    The particle swarm paradigm is employed to optimize single mixed refrigerant natural gas liquefaction process. Liquefaction design involves multivariable problem solving and non-optimal execution of these variables can waste energy and contribute to process irreversibilities. Design optimization requires these variables to be optimized simultaneously; minimizing the compression energy requirement is selected as the optimization objective. Liquefaction is modeled using Honeywell UniSim Design ™ and the resulting rigorous model is connected with the particle swarm paradigm coded in MATLAB. Design constraints are folded into the objective function using the penalty function method. Optimization successfully improved efficiency by reducing the compression energy requirement by ca. 10% compared with the base case. -- Highlights: ► The particle swarm paradigm (PSP) is employed for design optimization of SMR NG liquefaction process. ► Rigorous SMR process model based on UniSim is connected with PSP coded in MATLAB. ► Stochastic features of PSP give more confidence in the optimality of complex nonlinear problems. ► Optimization with PSP notably improves energy efficiency of the SMR process.

  9. Strategies for Enhancing Nonlinear Internal Model Control of pH Processes

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Qiuping.; Rangaiah, G.P. [The National University of Singapore, Singapore (Singapore). Dept. of Chemical and Environmental Engineering

    1999-02-01

    Control of neutralization processes is very difficult due to nonlinear dynamics, different types of disturbances and modeling errors. The objective of the paper is to evaluate two strategies (augmented internal model control, AuIMC and adaptive internal model control, AdIMC) for enhancing pH control by nonlinear internal model control (NIMC). A NIMC controller is derived directly form input output linearization. The AuIMC is composed of NIMC and an additional loop through which the difference between the process and model outputs is fed back and added to the input of the controller. For the AdIMC, and adaptive law with two tuning parameters is proposed for estimating the unknown parameter. Both AuIMC and AdIMC are extensively tested via simulation for pH neutralization. The theoretical and simulation results show that both the proposed strategies can reduce the effect of modeling errors and disturbances, and thereby enhance the performance of NIMC for pH processes. (author)

  10. An integrated nonlinear optical loop mirror in silicon photonics for all-optical signal processing

    Directory of Open Access Journals (Sweden)

    Zifei Wang

    2018-02-01

    Full Text Available The nonlinear optical loop mirror (NOLM has been studied for several decades and has attracted considerable attention for applications in high data rate optical communications and all-optical signal processing. The majority of NOLM research has focused on silica fiber-based implementations. While various fiber designs have been considered to increase the nonlinearity and manage dispersion, several meters to hundreds of meters of fiber are still required. On the other hand, there is increasing interest in developing photonic integrated circuits for realizing signal processing functions. In this paper, we realize the first-ever passive integrated NOLM in silicon photonics and demonstrate its application for all-optical signal processing. In particular, we show wavelength conversion of 10 Gb/s return-to-zero on-off keying (RZ-OOK signals over a wavelength range of 30 nm with error-free operation and a power penalty of less than 2.5 dB, we achieve error-free nonreturn to zero (NRZ-to-RZ modulation format conversion at 10 Gb/s also with a power penalty of less than 2.8 dB, and we obtain error-free all-optical time-division demultiplexing of a 40 Gb/s RZ-OOK data signal into its 10 Gb/s tributary channels with a maximum power penalty of 3.5 dB.

  11. Improving industrial designers work process by involving user research

    DEFF Research Database (Denmark)

    Dai, Zheng; Ómarsson, Ólafur

    2011-01-01

    With changing times, new technologies and more opinionated consumers, the modern industrial designer has found himself in need of fresher and more up to date approaches in his daily work. In a fast moving industry, the designer needs to keep a thinking process of dynamic and subjective attitude...... will give the grounding for believing that the industrial designer needs to adopt user research methods to a level where he can still continue to work under the very nature of industrial design that has made it a successful practice for the last century. The combing of the approaches and attitude will help....... User research is part of user centered design (UCD). UCD has a reputation for subjective and reflective practice. In this paper there are two example cases. One is conducted by a classical industrial design process, and another is costing half of energy and time in user research. These examples...

  12. Physical Processes Involved In Yellow Sea Solitary Waves

    Science.gov (United States)

    Warn-Varnas, A.; Chin-Bing, S.; King, D.; Lamb, K.; Hawkins, J.; Teixeira, M.

    The study area is located south of the Shandong peninsula. In this area, soliton gener- ation and propagation studies are per formed with the Lamb(1994) model. The model is nonhydrostatic and is formulated in 2 1/2 dimensions for terrain following c oordi- nates. In the area, 20 to 30 m topographic variations over distances of 10 to 20 km are found to occur in the digit al atlas of Choi (1999). The area is shallow with maximum depths ranging from 40 m to 70 m. Along the southern boundary of the region the semi-diurnal tidal strength magnitude varies from .6 m/sec to 1.2 m/sec, Fang(1994). We show that, for sum mer conditions, the existing physical processes associated with the semi-diurnal tidal flow over the topographic variations , in the shelfbreak region, lead to the formation of internal bores in the model simulations. Through acting phys- ical proce sses, the internal bores propagate on and off the shelf. A disintegration process of internal bores into solitary waves occ urs through frequency and ampli- tude dispersion. SAR observations of the area show images containing six events con- sisting of internal bores and solitary waves that travel in a well-defined direction for two and a half days. The origin of the trains appeared to be at a point along a steep topo graphic drop. The SAR observations are used for guiding and tuning the model simulations, by comparing spectra of observed and modeled wavelengths. The tuned model yields wavelengths that are within a factor of 2 of the SAR data. The modeled amp litudes are within a factor of 2 of amplitudes obtained with a two-layer model and the SAR data The signature on the acoustical field of ongoing physical processes through the interaction of the resultant oceanic struct ure with the acoustical field is pursued. Internal bore and solitary wave structures interact with the acoustic field. A re distribution of acoustical energy to higher acoustical modes occurs at some fre- quencies. Mode decomposition of the

  13. Mode-selective mapping and control of vectorial nonlinear-optical processes in multimode photonic-crystal fibers.

    Science.gov (United States)

    Hu, Ming-Lie; Wang, Ching-Yue; Song, You-Jian; Li, Yan-Feng; Chai, Lu; Serebryannikov, Evgenii; Zheltikov, Aleksei

    2006-02-06

    We demonstrate an experimental technique that allows a mapping of vectorial nonlinear-optical processes in multimode photonic-crystal fibers (PCFs). Spatial and polarization modes of PCFs are selectively excited in this technique by varying the tilt angle of the input beam and rotating the polarization of the input field. Intensity spectra of the PCF output plotted as a function of the input field power and polarization then yield mode-resolved maps of nonlinear-optical interactions in multimode PCFs, facilitating the analysis and control of nonlinear-optical transformations of ultrashort laser pulses in such fibers.

  14. Fabrication of highly nonlinear germano-silicate glass optical fiber incorporated with PbTe semiconductor quantum dots using atomization doping process and its optical nonlinearity.

    Science.gov (United States)

    Ju, Seongmin; Watekar, Pramod R; Han, Won-Taek

    2011-01-31

    Germano-silicate glass optical fiber incorporated with PbTe semiconductor quantum dots (SQDs) in the core was fabricated by using the atomization process in modified chemical vapor deposition (MCVD) process. The absorption bands attributed to PbTe semiconductor quantum dots in the fiber core were found to appear at around 687 nm and 1055 nm. The nonlinear refractive index measured by the long-period fiber grating (LPG) pair method upon pumping with laser diode at 976.4 nm was estimated to be ~1.5 × 10(-16) m2/W.

  15. 44 CFR 5.8 - Records involved in litigation or other judicial process.

    Science.gov (United States)

    2010-10-01

    ... litigation or other judicial process. 5.8 Section 5.8 Emergency Management and Assistance FEDERAL EMERGENCY... Provisions § 5.8 Records involved in litigation or other judicial process. Where there is reason to believe that any records requested may be involved in litigation or other judicial process in which the United...

  16. Imitation learning of Non-Linear Point-to-Point Robot Motions using Dirichlet Processes

    DEFF Research Database (Denmark)

    Krüger, Volker; Tikhanoff, Vadim; Natale, Lorenzo

    2012-01-01

    In this paper we discuss the use of the infinite Gaussian mixture model and Dirichlet processes for learning robot movements from demonstrations. Starting point of this work is an earlier paper where the authors learn a non-linear dynamic robot movement model from a small number of observations....... The model in that work is learned using a classical finite Gaussian mixture model (FGMM) where the Gaussian mixtures are appropriately constrained. The problem with this approach is that one needs to make a good guess for how many mixtures the FGMM should use. In this work, we generalize this approach...... our algorithm on the same data that was used in [5], where the authors use motion capture devices to record the demonstrations. As further validation we test our approach on novel data acquired on our iCub in a different demonstration scenario in which the robot is physically driven by the human...

  17. Non-linear multivariable predictive control of an alcoholic fermentation process using functional link networks

    Directory of Open Access Journals (Sweden)

    Luiz Augusto da Cruz Meleiro

    2005-06-01

    Full Text Available In this work a MIMO non-linear predictive controller was developed for an extractive alcoholic fermentation process. The internal model of the controller was represented by two MISO Functional Link Networks (FLNs, identified using simulated data generated from a deterministic mathematical model whose kinetic parameters were determined experimentally. The FLN structure presents as advantages fast training and guaranteed convergence, since the estimation of the weights is a linear optimization problem. Besides, the elimination of non-significant weights generates parsimonious models, which allows for fast execution in an MPC-based algorithm. The proposed algorithm showed good potential in identification and control of non-linear processes.Neste trabalho um controlador preditivo não linear multivariável foi desenvolvido para um processo de fermentação alcoólica extrativa. O modelo interno do controlador foi representado por duas redes do tipo Functional Link (FLN, identificadas usando dados de simulação gerados a partir de um modelo validado experimentalmente. A estrutura FLN apresenta como vantagem o treinamento rápido e convergência garantida, já que a estimação dos seus pesos é um problema de otimização linear. Além disso, a eliminação de pesos não significativos gera modelos parsimoniosos, o que permite a rápida execução em algoritmos de controle preditivo baseado em modelo. Os resultados mostram que o algoritmo proposto tem grande potencial para identificação e controle de processos não lineares.

  18. A Model Predictive Algorithm for Active Control of Nonlinear Noise Processes

    Directory of Open Access Journals (Sweden)

    Qi-Zhi Zhang

    2005-01-01

    Full Text Available In this paper, an improved nonlinear Active Noise Control (ANC system is achieved by introducing an appropriate secondary source. For ANC system to be successfully implemented, the nonlinearity of the primary path and time delay of the secondary path must be overcome. A nonlinear Model Predictive Control (MPC strategy is introduced to deal with the time delay in the secondary path and the nonlinearity in the primary path of the ANC system. An overall online modeling technique is utilized for online secondary path and primary path estimation. The secondary path is estimated using an adaptive FIR filter, and the primary path is estimated using a Neural Network (NN. The two models are connected in parallel with the two paths. In this system, the mutual disturbances between the operation of the nonlinear ANC controller and modeling of the secondary can be greatly reduced. The coefficients of the adaptive FIR filter and weight vector of NN are adjusted online. Computer simulations are carried out to compare the proposed nonlinear MPC method with the nonlinear Filter-x Least Mean Square (FXLMS algorithm. The results showed that the convergence speed of the proposed nonlinear MPC algorithm is faster than that of nonlinear FXLMS algorithm. For testing the robust performance of the proposed nonlinear ANC system, the sudden changes in the secondary path and primary path of the ANC system are considered. Results indicated that the proposed nonlinear ANC system can rapidly track the sudden changes in the acoustic paths of the nonlinear ANC system, and ensure the adaptive algorithm stable when the nonlinear ANC system is time variable.

  19. The Havriliak-Negami susceptibility as a nonlinear and nonlocal process

    International Nuclear Information System (INIS)

    Miskinis, Paulius

    2009-01-01

    A theoretical substantiation of the Cole-Cole, Cole-Davidson and Havriliak-Negami types of susceptibilities is presented. These types of susceptibility are shown to be a manifestation of weak nonlocality and nonlinearity. The Debye susceptibility corresponds to linear and local relaxation, the Cole-Cole susceptibility being linear and nonlocal; the Cole-Davidson susceptibility is nonlinear and local and the Havriliak-Negami susceptibility corresponds to nonlinear and nonlocal relaxation.

  20. Maglev Train Signal Processing Architecture Based on Nonlinear Discrete Tracking Differentiator

    Directory of Open Access Journals (Sweden)

    Zhiqiang Wang

    2018-05-01

    Full Text Available In a maglev train levitation system, signal processing plays an important role for the reason that some sensor signals are prone to be corrupted by noise due to the harsh installation and operation environment of sensors and some signals cannot be acquired directly via sensors. Based on these concerns, an architecture based on a new type of nonlinear second-order discrete tracking differentiator is proposed. The function of this signal processing architecture includes filtering signal noise and acquiring needed signals for levitation purposes. The proposed tracking differentiator possesses the advantages of quick convergence, no fluttering, and simple calculation. Tracking differentiator’s frequency characteristics at different parameter values are studied in this paper. The performance of this new type of tracking differentiator is tested in a MATLAB simulation and this tracking-differentiator is implemented in Very-High-Speed Integrated Circuit Hardware Description Language (VHDL. In the end, experiments are conducted separately on a test board and a maglev train model. Simulation and experiment results show that the performance of this novel signal processing architecture can fulfill the real system requirement.

  1. Maglev Train Signal Processing Architecture Based on Nonlinear Discrete Tracking Differentiator.

    Science.gov (United States)

    Wang, Zhiqiang; Li, Xiaolong; Xie, Yunde; Long, Zhiqiang

    2018-05-24

    In a maglev train levitation system, signal processing plays an important role for the reason that some sensor signals are prone to be corrupted by noise due to the harsh installation and operation environment of sensors and some signals cannot be acquired directly via sensors. Based on these concerns, an architecture based on a new type of nonlinear second-order discrete tracking differentiator is proposed. The function of this signal processing architecture includes filtering signal noise and acquiring needed signals for levitation purposes. The proposed tracking differentiator possesses the advantages of quick convergence, no fluttering, and simple calculation. Tracking differentiator's frequency characteristics at different parameter values are studied in this paper. The performance of this new type of tracking differentiator is tested in a MATLAB simulation and this tracking-differentiator is implemented in Very-High-Speed Integrated Circuit Hardware Description Language (VHDL). In the end, experiments are conducted separately on a test board and a maglev train model. Simulation and experiment results show that the performance of this novel signal processing architecture can fulfill the real system requirement.

  2. Dynamics of a photorefractive response and competition of nonlinear processes in self-pumping double phase-conjugate mirrors

    International Nuclear Information System (INIS)

    Mogaddam, Mehran Wahdani; Shuvalov, Vladimir V

    2005-01-01

    The dynamics of formation of a nonlinear response of a double phase-conjugate (PC) BaTiO 3 mirror is calculated. It is shown that because of competition between processes of different types (related to the presence of several PC channels, the local and nonlocal components of the photorefractive nonlinearity), the transient and dynamic lasing regimes for this mirror can be substantially different. It is found that the development of lasing begins with the successive formation and phasing of dynamic holograms of two different types (two PC channels). It is shown that even under optimal conditions, the lasing regime is not stationary due to competition between processes of different types, and the parameters of output fields fluctuate in time in a nontrivial way (due to the presence of the in-phase and out-of-phase components). Several scenarios of transition to the dynamic chaos are described. (nonlinear optical phenomena)

  3. Patient involvement in a scientific advisory process: setting the research agenda for medical products.

    NARCIS (Netherlands)

    Elberse, J.E.; Pittens, C.A.C.M.; de Cock Buning, J.T.; Broerse, J.E.W.

    2012-01-01

    Patient involvement in scientific advisory processes could lead to more societally relevant advice. This article describes a case study wherein the Health Council of the Netherlands involved patient groups in an advisory process with a predefined focus: setting a research agenda for medical products

  4. Digital signals processing using non-linear orthogonal transformation in frequency domain

    Directory of Open Access Journals (Sweden)

    Ivanichenko E.V.

    2017-12-01

    Full Text Available The rapid progress of computer technology in recent decades led to a wide introduction of methods of digital information processing practically in all fields of scientific research. In this case, among various applications of computing one of the most important places is occupied by digital processing systems signals (DSP that are used in data processing remote solution tasks of navigation of aerospace and marine objects, communications, radiophysics, digital optics and in a number of other applications. Digital Signal Processing (DSP is a dynamically developing an area that covers both technical and software tools. Related areas for digital signal processing are theory information, in particular, the theory of optimal signal reception and theory pattern recognition. In the first case, the main problem is signal extraction against a background of noise and interference of a different physical nature, and in the second - automatic recognition, i.e. classification and signal identification. In the digital processing of signals under a signal, we mean its mathematical description, i.e. a certain real function, containing information on the state or behavior of a physical system under an event that can be defined on a continuous or discrete space of time variation or spatial coordinates. In the broad sense, DSP systems mean a complex algorithmic, hardware and software. As a rule, systems contain specialized technical means of preliminary (or primary signal processing and special technical means for secondary processing of signals. Means of pretreatment are designed to process the original signals observed in general case against a background of random noise and interference of a different physical nature and represented in the form of discrete digital samples, for the purpose of detecting and selection (selection of the useful signal and evaluation characteristics of the detected signal. A new method of digital signal processing in the frequency

  5. Nonlinear digital signal processing in mental health: characterization of major depression using instantaneous entropy measures of heartbeat dynamics.

    Science.gov (United States)

    Valenza, Gaetano; Garcia, Ronald G; Citi, Luca; Scilingo, Enzo P; Tomaz, Carlos A; Barbieri, Riccardo

    2015-01-01

    Nonlinear digital signal processing methods that address system complexity have provided useful computational tools for helping in the diagnosis and treatment of a wide range of pathologies. More specifically, nonlinear measures have been successful in characterizing patients with mental disorders such as Major Depression (MD). In this study, we propose the use of instantaneous measures of entropy, namely the inhomogeneous point-process approximate entropy (ipApEn) and the inhomogeneous point-process sample entropy (ipSampEn), to describe a novel characterization of MD patients undergoing affective elicitation. Because these measures are built within a nonlinear point-process model, they allow for the assessment of complexity in cardiovascular dynamics at each moment in time. Heartbeat dynamics were characterized from 48 healthy controls and 48 patients with MD while emotionally elicited through either neutral or arousing audiovisual stimuli. Experimental results coming from the arousing tasks show that ipApEn measures are able to instantaneously track heartbeat complexity as well as discern between healthy subjects and MD patients. Conversely, standard heart rate variability (HRV) analysis performed in both time and frequency domains did not show any statistical significance. We conclude that measures of entropy based on nonlinear point-process models might contribute to devising useful computational tools for care in mental health.

  6. Stakeholder involvement activities in Slovakia. NRA's Commitment to Transparent Regulatory Process. Stakeholder Involvement in the French Regulatory Process - From Public Information to Public Participation. Stakeholder involvement in nuclear decision making in the Russian Federation

    International Nuclear Information System (INIS)

    Ziakova, Marta Chairperson; Nuclear Regulatory Authority of the Slovak Republic; Nuclear Regulation Authority - NRA; Ferapontov, Alexey

    2017-01-01

    Session 2 focused on the regulatory perspectives related to stakeholder involvement in the regulatory decision-making process. Presentations provided the audience with information regarding the international and national legal framework implemented in the Slovak Republic, in France, in Japan and in Russia. Examples of stakeholder involvement, as well as some tools used for this purpose, were presented and discussed. The value of consistency and complementarity between international and national requirements was highlighted. Presentations and discussion confirmed the very close tie between the way the stakeholder involvement process is conducted and the public confidence and perception of reliability the regulatory body may gain, or lose. The four presentations confirmed that stakeholder involvement is a key challenge for maintaining regulatory body credibility, independence and legitimacy. All countries confirmed their commitment to trying to make their stakeholder involvement processes as open, visible, transparent and comprehensive as possible. Involvement represents a long and permanent process which requires investment of time, human resources and money, as well as the ability to reach out, to listen, to share, and to take input into account, while keeping in view the goal of delivering decisions that are as rational and objective as possible. Involving stakeholders is more than informing or communicating. The earlier the stakeholders are involved in the decision-making process, the greater the chance of success. If losing credibility is easy, all regulatory bodies agreed on the long process needed to recover it

  7. EGS Richardson AGU Chapman NVAG3 Conference: Nonlinear Variability in Geophysics: scaling and multifractal processes

    Directory of Open Access Journals (Sweden)

    D. Schertzer

    1994-01-01

    Full Text Available 1. The conference The third conference on "Nonlinear VAriability in Geophysics: scaling and multifractal processes" (NVAG 3 was held in Cargese, Corsica, Sept. 10-17, 1993. NVAG3 was joint American Geophysical Union Chapman and European Geophysical Society Richardson Memorial conference, the first specialist conference jointly sponsored by the two organizations. It followed NVAG1 (Montreal, Aug. 1986, NVAG2 (Paris, June 1988; Schertzer and Lovejoy, 1991, five consecutive annual sessions at EGS general assemblies and two consecutive spring AGU meeting sessions. As with the other conferences and workshops mentioned above, the aim was to develop confrontation between theories and experiments on scaling/multifractal behaviour of geophysical fields. Subjects covered included climate, clouds, earthquakes, atmospheric and ocean dynamics, tectonics, precipitation, hydrology, the solar cycle and volcanoes. Areas of focus included new methods of data analysis (especially those used for the reliable estimation of multifractal and scaling exponents, as well as their application to rapidly growing data bases from in situ networks and remote sensing. The corresponding modelling, prediction and estimation techniques were also emphasized as were the current debates about stochastic and deterministic dynamics, fractal geometry and multifractals, self-organized criticality and multifractal fields, each of which was the subject of a specific general discussion. The conference started with a one day short course of multifractals featuring four lectures on a Fundamentals of multifractals: dimension, codimensions, codimension formalism, b Multifractal estimation techniques: (PDMS, DTM, c Numerical simulations, Generalized Scale Invariance analysis, d Advanced multifractals, singular statistics, phase transitions, self-organized criticality and Lie cascades (given by D. Schertzer and S. Lovejoy, detailed course notes were sent to participants shortly after the

  8. EGS Richardson AGU Chapman NVAG3 Conference: Nonlinear Variability in Geophysics: scaling and multifractal processes

    Science.gov (United States)

    Schertzer, D.; Lovejoy, S.

    1. The conference The third conference on "Nonlinear VAriability in Geophysics: scaling and multifractal processes" (NVAG 3) was held in Cargese, Corsica, Sept. 10-17, 1993. NVAG3 was joint American Geophysical Union Chapman and European Geophysical Society Richardson Memorial conference, the first specialist conference jointly sponsored by the two organizations. It followed NVAG1 (Montreal, Aug. 1986), NVAG2 (Paris, June 1988; Schertzer and Lovejoy, 1991), five consecutive annual sessions at EGS general assemblies and two consecutive spring AGU meeting sessions. As with the other conferences and workshops mentioned above, the aim was to develop confrontation between theories and experiments on scaling/multifractal behaviour of geophysical fields. Subjects covered included climate, clouds, earthquakes, atmospheric and ocean dynamics, tectonics, precipitation, hydrology, the solar cycle and volcanoes. Areas of focus included new methods of data analysis (especially those used for the reliable estimation of multifractal and scaling exponents), as well as their application to rapidly growing data bases from in situ networks and remote sensing. The corresponding modelling, prediction and estimation techniques were also emphasized as were the current debates about stochastic and deterministic dynamics, fractal geometry and multifractals, self-organized criticality and multifractal fields, each of which was the subject of a specific general discussion. The conference started with a one day short course of multifractals featuring four lectures on a) Fundamentals of multifractals: dimension, codimensions, codimension formalism, b) Multifractal estimation techniques: (PDMS, DTM), c) Numerical simulations, Generalized Scale Invariance analysis, d) Advanced multifractals, singular statistics, phase transitions, self-organized criticality and Lie cascades (given by D. Schertzer and S. Lovejoy, detailed course notes were sent to participants shortly after the conference). This

  9. Mamdani-Fuzzy Modeling Approach for Quality Prediction of Non-Linear Laser Lathing Process

    Science.gov (United States)

    Sivaraos; Khalim, A. Z.; Salleh, M. S.; Sivakumar, D.; Kadirgama, K.

    2018-03-01

    Lathing is a process to fashioning stock materials into desired cylindrical shapes which usually performed by traditional lathe machine. But, the recent rapid advancements in engineering materials and precision demand gives a great challenge to the traditional method. The main drawback of conventional lathe is its mechanical contact which brings to the undesirable tool wear, heat affected zone, finishing, and dimensional accuracy especially taper quality in machining of stock with high length to diameter ratio. Therefore, a novel approach has been devised to investigate in transforming a 2D flatbed CO2 laser cutting machine into 3D laser lathing capability as an alternative solution. Three significant design parameters were selected for this experiment, namely cutting speed, spinning speed, and depth of cut. Total of 24 experiments were performed with eight (8) sequential runs where they were then replicated three (3) times. The experimental results were then used to establish Mamdani - Fuzzy predictive model where it yields the accuracy of more than 95%. Thus, the proposed Mamdani - Fuzzy modelling approach is found very much suitable and practical for quality prediction of non-linear laser lathing process for cylindrical stocks of 10mm diameter.

  10. Oligopoly games with nonlinear demand and cost functions: Two boundedly rational adjustment processes

    International Nuclear Information System (INIS)

    Naimzada, Ahmad K.; Sbragia, Lucia

    2006-01-01

    We consider a Cournot oligopoly game, where firms produce an homogenous good and the demand and cost functions are nonlinear. These features make the classical best reply solution difficult to be obtained, even if players have full information about their environment. We propose two different kinds of repeated games based on a lower degree of rationality of the firms, on a reduced information set and reduced computational capabilities. The first adjustment mechanism is called 'Local Monopolistic Approximation' (LMA). First firms get the correct local estimate of the demand function and then they use such estimate in a linear approximation of the demand function where the effects of the competitors' outputs are ignored. On the basis of this subjective demand function they solve their profit maximization problem. By using the second adjustment process, that belongs to a class of adaptive mechanisms known in the literature as 'Gradient Dynamics' (GD), firms do not solve any optimization problem, but they adjust their production in the direction indicated by their (correct) estimate of the marginal profit. Both these repeated games may converge to a Cournot-Nash equilibrium, i.e. to the equilibrium of the best reply dynamics. We compare the properties of the two different dynamical systems that describe the time evolution of the oligopoly games under the two adjustment mechanisms, and we analyze the conditions that lead to non-convergence and complex dynamic behaviors. The paper extends the results of other authors that consider similar adjustment processes assuming linear cost functions or linear demand functions

  11. Separation of irradiance and reflectance from observed color images by logarithmical nonlinear diffusion process

    Science.gov (United States)

    Saito, Takahiro; Takahashi, Hiromi; Komatsu, Takashi

    2006-02-01

    The Retinex theory was first proposed by Land, and deals with separation of irradiance from reflectance in an observed image. The separation problem is an ill-posed problem. Land and others proposed various Retinex separation algorithms. Recently, Kimmel and others proposed a variational framework that unifies the previous Retinex algorithms such as the Poisson-equation-type Retinex algorithms developed by Horn and others, and presented a Retinex separation algorithm with the time-evolution of a linear diffusion process. However, the Kimmel's separation algorithm cannot achieve physically rational separation, if true irradiance varies among color channels. To cope with this problem, we introduce a nonlinear diffusion process into the time-evolution. Moreover, as to its extension to color images, we present two approaches to treat color channels: the independent approach to treat each color channel separately and the collective approach to treat all color channels collectively. The latter approach outperforms the former. Furthermore, we apply our separation algorithm to a high quality chroma key in which before combining a foreground frame and a background frame into an output image a color of each pixel in the foreground frame are spatially adaptively corrected through transformation of the separated irradiance. Experiments demonstrate superiority of our separation algorithm over the Kimmel's separation algorithm.

  12. Nonlinear system identification of the reduction nickel oxide smelting process in electric arc furnace

    Science.gov (United States)

    Gubin, V.; Firsov, A.

    2018-03-01

    As the title implies the article describes the nonlinear system identification of the reduction smelting process of nickel oxide in electric arc furnaces. It is suggested that for operational control ratio of components of the charge must be solved the problem of determining the qualitative composition of the melt in real time. The use of 0th harmonic of phase voltage AC furnace as an indirect measure of the melt composition is proposed. Brief description of the mechanism of occurrence and nature of the non-zero 0th harmonic of the AC voltage of the arc is given. It is shown that value of 0th harmonic of the arc voltage is not function of electrical parameters but depends of the material composition of the melt. Processed industrial data are given. Hammerstein-Wiener model is used for description of the dependence of 0th harmonic of the furnace voltage from the technical parameters of melting furnace: the melt composition and current. Recommendations are given about the practical use of the model.

  13. Uncovering molecular relaxation processes with nonlinear spectroscopies in the deep UV

    International Nuclear Information System (INIS)

    West, Brantley A.; Molesky, Brian P.; Giokas, Paul G.; Moran, Andrew M.

    2013-01-01

    Highlights: • We discuss the outlook for multidimensional spectroscopies in the deep UV. • Photophysics are examined in small DNA components at cryogenic temperatures. • Wavepacket motions are detected in ring-opening systems with 2DUV spectroscopy. • Measurements of electronic wavepacket motions in molecules are proposed. - Abstract: Nonlinear laser spectroscopies in the deep UV spectral range are motivated by studies of biological systems and elementary processes in small molecules. This perspective article discusses recent technical advances in this area with a particular emphasis on diffractive optic based approaches to four-wave mixing spectroscopies. Applications to two classes of systems illustrate present experimental capabilities. First, experiments on DNA components at cryogenic temperatures are used to uncover features of excited state potential energy surfaces and vibrational cooling mechanisms. Second, sub-200 fs internal conversion processes and coherent wavepacket motions are investigated in cyclohexadiene and α-terpinene. Finally, we propose new experimental directions that combine methods for producing few-cycle UV laser pulses in noble gases with incoherent detection methods (e.g., photoionization) in experiments with time resolution near a singlefemtosecond. These measurements are motivated by knowledge of extremely fast non-adiabatic dynamics and the resolution of electronic wavepacket motions in molecules

  14. Optimization of Nonlinear Figure-of-Merits of Integrated Power MOSFETs in Partial SOI Process

    DEFF Research Database (Denmark)

    Fan, Lin; Jørgensen, Ivan Harald Holger; Knott, Arnold

    2016-01-01

    State-of-the-art power semiconductor industry uses figure-of-merits (FOMs) for technology-to-technology and/or device-to-device comparisons. However, the existing FOMs are fundamentally nonlinear due to the nonlinearities of the parameters such as the gate charge and the output charge versus...

  15. Nonlinear PI Control with Adaptive Interaction Algorithm for Multivariable Wastewater Treatment Process

    Directory of Open Access Journals (Sweden)

    S. I. Samsudin

    2014-01-01

    Full Text Available The wastewater treatment plant (WWTP is highly known with the nonlinearity of the control parameters, thus it is difficult to be controlled. In this paper, the enhancement of nonlinear PI controller (ENon-PI to compensate the nonlinearity of the activated sludge WWTP is proposed. The ENon-PI controller is designed by cascading a sector-bounded nonlinear gain to linear PI controller. The rate variation of the nonlinear gain kn is automatically updated based on adaptive interaction algorithm. Initiative to simplify the ENon-PI control structure by adapting kn has been proved by significant improvement under various dynamic influents. More than 30% of integral square error and 14% of integral absolute error are reduced compared to benchmark PI for DO control and nitrate in nitrogen removal control. Better average effluent qualities, less number of effluent violations, and lower aeration energy consumption resulted.

  16. A kernel-based approach to MIMO LPV state-space identification and application to a nonlinear process system

    NARCIS (Netherlands)

    Rizvi, S.Z.; Mohammadpour, J.; Toth, R.; Meskin, N.

    2015-01-01

    This paper first describes the development of a nonparametric identification method for linear parameter-varying (LPV) state-space models and then applies it to a nonlinear process system. The proposed method uses kernel-based least-squares support vector machines (LS-SVM). While parametric

  17. Optimal Constant-Stress Accelerated Degradation Test Plans Using Nonlinear Generalized Wiener Process

    Directory of Open Access Journals (Sweden)

    Zhen Chen

    2016-01-01

    Full Text Available Accelerated degradation test (ADT has been widely used to assess highly reliable products’ lifetime. To conduct an ADT, an appropriate degradation model and test plan should be determined in advance. Although many historical studies have proposed quite a few models, there is still room for improvement. Hence we propose a Nonlinear Generalized Wiener Process (NGWP model with consideration of the effects of stress level, product-to-product variability, and measurement errors for a higher estimation accuracy and a wider range of use. Then under the constraints of sample size, test duration, and test cost, the plans of constant-stress ADT (CSADT with multiple stress levels based on the NGWP are designed by minimizing the asymptotic variance of the reliability estimation of the products under normal operation conditions. An optimization algorithm is developed to determine the optimal stress levels, the number of units allocated to each level, inspection frequency, and measurement times simultaneously. In addition, a comparison based on degradation data of LEDs is made to show better goodness-of-fit of the NGWP than that of other models. Finally, optimal two-level and three-level CSADT plans under various constraints and a detailed sensitivity analysis are demonstrated through examples in this paper.

  18. Design and implementation of novel nonlinear processes in bulk and waveguide periodic structures

    Science.gov (United States)

    Kajal, Meenu

    The telecommunication networks are facing increasing demand to implement all-optical network infrastructure for enabling the wide deployment of new triple play high-speed services (e.g. IPTV, Video On Demand, Voice over IP). One of the challenges with such video broadcasting applications is that these are much more distributed and multi-point in nature unlike the traditional point-to-point communication networks. Currently deployed high-speed electronic components in the optical networks are incapable of handling the unprecedented bandwidth demand for real-time multimedia based broadcasting. The solution essentially lies in increasing the transparency of networks i.e. by replacing high speed signal processing electronics with all-optical signal processors capable of performing signal manipulations such as wavelength switching, time and wavelength division multiplexing, optical pulse compression etc. all in optical domain. This thesis aims at providing an all-optical solution for broadband wavelength conversion and tunable broadcasting, a crucial optical network component, based on quasi-phase-matched wave mixing in nonlinear materials. The quasi phase matching (QPM) technique allows phase matching in long crystal lengths by employing domain-inverted gratings to periodically reverse the sign of nonlinearity, known as periodic poling. This results into new frequency components with high conversion efficiency and has been successfully implemented towards various processes such as second harmonic generation (SHG), sum- and difference- frequency generation (SFG and DFG). Conventionally, the optical networks has an operation window of ˜35 nm centered at 1.55 mum, known as C-band. The wavelength conversion of a signal channel in C-band to an output channel also in the C-band has been demonstrated in periodically poled lithium niobate (PPLN) waveguides via the process of difference frequency mixing, cascaded SHG/DFG and cascaded SFG/DFG. While a DFG process utilized a

  19. Nonlinear time reversal signal processing techniques applied to acousto-mechanical imaging of complex materials

    Czech Academy of Sciences Publication Activity Database

    Dos Santos, S.; Dvořáková, Zuzana; Caliez, M.; Převorovský, Zdeněk

    2015-01-01

    Roč. 138, č. 3 (2015) ISSN 0001-4966 Institutional support: RVO:61388998 Keywords : acousto-mechanical characterization of skin aging * nonlinear elastic wave spectroscopy (NEWS) * PM-space statistical approach Subject RIV: BI - Acoustics

  20. Nonlinear processes in laser-produced dense plasma (observation of the fractional harmonics)

    International Nuclear Information System (INIS)

    Lyu, K.S.

    1988-01-01

    One of the main issues of laser plasma physics interactions is harmonic generation. The harmonic emission spectrum provides clues as to which non-linear processes take place in the plasma. Several effects contribute to a given line as judged from the complexity of the actual spectra. Unfolding of them has not been done satisfactorily yet. Harmonic lines with half integer or integer orders have been observed, but the physics are far from complete. In this dissertation research, we observed the usual second harmonic generation and a set of fractional harmonics which we believe have been observed for the first time in plasma physics. The plasma was produced by a high power laser and we have characterized its properties from the analysis of the radiation spectra, including the harmonic lines, as measured using the methods of transient spectroscopy. We produced the plasma with a Nd:glass laser which had a 65 nsec pulse width (FWHM) with a total energy of up to 6 Joules. The targets were steel alloys, copper, and aluminum. The harmonic generation from the plasma with a planar metal target was not strong. But, it became stronger when we made a dead hole (cavity) at the laser spot on the target surface. The second harmonic line appears first before the time of the peak of laser pulse. The fractional harmonics, which are related to the laser wavelength by rational number other than integers or half integers, appear near or after the time of the laser peak and weaker in UV wavelength range but stronger if some atomic emission line are near by. To understand the plasma evolution better, we developed computer simulation codes. The codes contain all relevant processes necessary to compute the plasma evolution

  1. Harnessing mode-selective nonlinear optics for on-chip multi-channel all-optical signal processing

    Directory of Open Access Journals (Sweden)

    Ming Ma

    2016-11-01

    Full Text Available All-optical signal processing based on nonlinear optical effects allows for the realization of important functions in telecommunications including wavelength conversion, optical multiplexing/demultiplexing, Fourier transformation, and regeneration, amongst others, on ultrafast time scales to support high data rate transmission. In integrated photonic subsystems, the majority of all-optical signal processing systems demonstrated to date typically process only a single channel at a time or perform a single processing function, which imposes a serious limitation on the functionality of integrated solutions. Here, we demonstrate how nonlinear optical effects can be harnessed in a mode-selective manner to perform simultaneous multi-channel (two and multi-functional optical signal processing (i.e., regenerative wavelength conversion in an integrated silicon photonic device. This approach, which can be scaled to a higher number of channels, opens up a new degree of freedom for performing a broad range of multi-channel nonlinear optical signal processing functions using a single integrated photonic device.

  2. Has patients' involvement in the decision-making process changed over time?

    NARCIS (Netherlands)

    Brink-Muinen, A. van den; Dulmen, A.M. van; Haes, H.C.J.M. de; Visser, A.P.; Schellevis, F.G.; Bensing, J.M.

    2006-01-01

    Objective: To get insight into the changes over time of patients' involvement in the decision-making process, and into the factors contributing to patients' involvement and general practitioners' (GPs) communication related to the Medical Treatment Act (MTA) Issues: information about treatment,

  3. Has patients’ involvement in the decision-making process changed over time?

    NARCIS (Netherlands)

    Brink-Muinen, A. van den; Dulmen, S.M. van; Haes, H.C.J.M. de; Visser, A.P.; Schellevis, F.G.; Bensing, J.

    2006-01-01

    Objective To get insight into the changes over time of patients’ involvement in the decision-making process, and into the factors contributing to patients’ involvement and general practitioners’ (GPs) communication related to the Medical Treatment Act (MTA) issues: information about treatment,

  4. Classification of processes involved in sharing individual participant data from clinical trials.

    Science.gov (United States)

    Ohmann, Christian; Canham, Steve; Banzi, Rita; Kuchinke, Wolfgang; Battaglia, Serena

    2018-01-01

    Background: In recent years, a cultural change in the handling of data from research has resulted in the strong promotion of a culture of openness and increased sharing of data. In the area of clinical trials, sharing of individual participant data involves a complex set of processes and the interaction of many actors and actions. Individual services/tools to support data sharing are available, but what is missing is a detailed, structured and comprehensive list of processes/subprocesses involved and tools/services needed. Methods : Principles and recommendations from a published data sharing consensus document are analysed in detail by a small expert group. Processes/subprocesses involved in data sharing are identified and linked to actors and possible services/tools. Definitions are adapted from the business process model and notation (BPMN) and applied in the analysis. Results: A detailed and comprehensive list of individual processes/subprocesses involved in data sharing, structured according to 9 main processes, is provided. Possible tools/services to support these processes/subprocesses are identified and grouped according to major type of support. Conclusions: The list of individual processes/subprocesses and tools/services identified is a first step towards development of a generic framework or architecture for sharing of data from clinical trials. Such a framework is strongly needed to give an overview of how various actors, research processes and services could form an interoperable system for data sharing.

  5. Nonlinear control of a multicomponent distillation process coupled with a binary distillation model as an EKF predictor.

    Science.gov (United States)

    Jana, Amiya Kumar; Ganguly, Saibal; Samanta, Amar Nath

    2006-10-01

    The work is devoted to design the globally linearizing control (GLC) strategy for a multicomponent distillation process. The control system is comprised with a nonlinear transformer, a nonlinear closed-loop state estimator [extended Kalman filter (EKF)], and a linear external controller [conventional proportional integral (PI) controller]. The model of a binary distillation column has been used as a state predictor to avoid huge design complexity of the EKF estimator. The binary components are the light key and the heavy key of the multicomponent system. The proposed GLC-EKF (GLC in conjunction with EKF) control algorithm has been compared with the GLC-ROOLE [GLC coupled with reduced-order open-loop estimator (ROOLE)] and the dual-loop PI controller based on set point tracking and disturbance rejection performance. Despite huge process/predictor mismatch, the superiority of the GLC-EKF has been inspected over the GLC-ROOLE control structure.

  6. Identification of defect distribution at ferroelectric domain walls from evolution of nonlinear dielectric response during the aging process

    Czech Academy of Sciences Publication Activity Database

    Mokrý, Pavel; Sluka, T.

    2016-01-01

    Roč. 93, č. 6 (2016), č. článku 064114. ISSN 2469-9950 R&D Projects: GA ČR(CZ) GA14-32228S Institutional support: RVO:61389021 Keywords : Nonlinear dielectric response * ferroelectric domain walls * aging process * phase field simulations Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 3.836, year: 2016 http://journals.aps.org/prb/abstract/10.1103/PhysRevB.93.064114

  7. A Quasi-Dynamic Optimal Control Strategy for Non-Linear Multivariable Processes Based upon Non-Quadratic Objective Functions

    Directory of Open Access Journals (Sweden)

    Jens G. Balchen

    1984-10-01

    Full Text Available The problem of systematic derivation of a quasi-dynamic optimal control strategy for a non-linear dynamic process based upon a non-quadratic objective function is investigated. The wellknown LQG-control algorithm does not lead to an optimal solution when the process disturbances have non-zero mean. The relationships between the proposed control algorithm and LQG-control are presented. The problem of how to constrain process variables by means of 'penalty' - terms in the objective function is dealt with separately.

  8. Involving patients in health technology funding decisions: stakeholder perspectives on processes used in Australia.

    Science.gov (United States)

    Lopes, Edilene; Street, Jackie; Carter, Drew; Merlin, Tracy

    2016-04-01

    Governments use a variety of processes to incorporate public perspectives into policymaking, but few studies have evaluated these processes from participants' point of view. The objective of this study was twofold: to understand the perspectives of selected stakeholders with regard to involvement processes used by Australian Advisory Committees to engage the public and patients; and to identify barriers and facilitators to participation. Twelve semi-structured interviews were conducted with representatives of different stakeholder groups involved in health technology funding decisions in Australia. Data were collected and analysed using a theoretical framework created by Rowe and Frewer, but adapted to more fully acknowledge issues of power and influence. Stakeholder groups disagreed as to what constitutes effective and inclusive patient involvement. Barriers reported by interviewees included poor communication, a lack of transparency, unworkable deadlines, and inadequate representativeness. Also described were problems associated with defining the task for patients and their advocates and with the timing of patient input in the decision-making process. Interviewees suggested that patient participation could be improved by increasing the number of patient organizations engaged in processes and including those organizations at different stages of decision making, especially earlier. The different evaluations made by stakeholder groups appear to be underpinned by contrasting conceptions of public involvement and its value, in line with Graham Martin's work which distinguishes between 'technocratic' and 'democratic' public involvement. Understanding stakeholders' perspectives and the contrasting conceptions of public involvement could foster future agreement on which processes should be used to involve the public in decision making. © 2015 John Wiley & Sons Ltd.

  9. Nonlinear process in the mode transition in typical strut-based and cavity-strut based scramjet combustors

    Science.gov (United States)

    Yan, Li; Liao, Lei; Huang, Wei; Li, Lang-quan

    2018-04-01

    The analysis of nonlinear characteristics and control of mode transition process is the crucial issue to enhance the stability and reliability of the dual-mode scramjet engine. In the current study, the mode transition processes in both strut-based combustor and cavity-strut based combustor are numerically studied, and the influence of the cavity on the transition process is analyzed in detail. The simulations are conducted by means of the Reynolds averaged Navier-Stokes (RANS) equations coupled with the renormalization group (RNG) k-ε turbulence model and the single-step chemical reaction mechanism, and this numerical approach is proved to be valid by comparing the predicted results with the available experimental shadowgraphs in the open literature. During the mode transition process, an obvious nonlinear property is observed, namely the unevenly variations of pressure along the combustor. The hysteresis phenomenon is more obvious upstream of the flow field. For the cavity-strut configuration, the whole flow field is more inclined to the supersonic state during the transition process, and it is uneasy to convert to the ramjet mode. In the scram-to-ram transition process, the process would be more stable, and the hysteresis effect would be reduced in the ram-to-scram transition process.

  10. Pseudorandom numbers: evolutionary models in image processing, biology, and nonlinear dynamic systems

    Science.gov (United States)

    Yaroslavsky, Leonid P.

    1996-11-01

    We show that one can treat pseudo-random generators, evolutionary models of texture images, iterative local adaptive filters for image restoration and enhancement and growth models in biology and material sciences in a unified way as special cases of dynamic systems with a nonlinear feedback.

  11. Investigation of mental fatigue through EEG signal processing based on nonlinear analysis: Symbolic dynamics

    International Nuclear Information System (INIS)

    Azarnoosh, Mahdi; Motie Nasrabadi, Ali; Mohammadi, Mohammad Reza; Firoozabadi, Mohammad

    2011-01-01

    Highlights: Mental fatigue indices’ variation discussed during simple long-term attentive task. Symbolic dynamics of reaction time and EEG signal determine mental state variation. Nonlinear quantifiers such as entropy can display chaotic behaviors of the brain. Frontal and central lobes of the brain are effective in attention investigations. Mental fatigue causes a reduction in the complexity of the brain’s activity. Abstract: To investigate nonlinear analysis of attention physiological indices this study used a simple repetitive attentive task in four consecutive trials that resulted in mental fatigue. Traditional performance indices, such as reaction time, error responses, and EEG signals, were simultaneously recorded to evaluate differences between the trials. Performance indices analysis demonstrated that a selected task leads to mental fatigue. In addition, the study aimed to find a method to determine mental fatigue based on nonlinear analysis of EEG signals. Symbolic dynamics was selected as a qualitative method used to extract some quantitative qualifiers such as entropy. This method was executed on the reaction time of responses, and EEG signals to distinguish mental states. The results revealed that nonlinear analysis of reaction time, and EEG signals of the frontal and central lobes of the brain could differentiate between attention, and occurrence of mental fatigue in trials. In addition, the trend of entropy variation displayed a reduction in the complexity of mental activity as fatigue occurred.

  12. The purchase decision process and involvement of the elderly regarding nonprescription products.

    Science.gov (United States)

    Reisenwitz, T H; Wimbish, G J

    1997-01-01

    The elderly or senior citizen is a large and growing market segment that purchases a disproportionate amount of health care products, particularly nonprescription products. This study attempts to examine the elderly's level of involvement (high versus low) and their purchase decision process regarding nonprescription or over-the-counter (OTC) products. Frequencies and percentages are calculated to indicate level of involvement as well as purchase decision behavior. Previous research is critiqued and managerial implications are discussed.

  13. Stakeholder involvement in stages of a participatory process illustrated in interior design cases

    DEFF Research Database (Denmark)

    Vink, Peter; van Rhijn, Gu; Seim, Rikke

    2008-01-01

    In a previous study (Vink et al., 2008) an overview was made of the involvement of different stakeholders in a participatory design process. In this paper this overview was used to describe four participatory design cases focused on improvising productivity, health, and comfort by interior design....... It appeared that this overview is useful to describe the involvement in participatory interior design projects. However, it can only serve as an initial benchmark as much is dependent on the specific case at hand....

  14. On the stability and dynamics of stochastic spiking neuron models: Nonlinear Hawkes process and point process GLMs.

    Science.gov (United States)

    Gerhard, Felipe; Deger, Moritz; Truccolo, Wilson

    2017-02-01

    Point process generalized linear models (PP-GLMs) provide an important statistical framework for modeling spiking activity in single-neurons and neuronal networks. Stochastic stability is essential when sampling from these models, as done in computational neuroscience to analyze statistical properties of neuronal dynamics and in neuro-engineering to implement closed-loop applications. Here we show, however, that despite passing common goodness-of-fit tests, PP-GLMs estimated from data are often unstable, leading to divergent firing rates. The inclusion of absolute refractory periods is not a satisfactory solution since the activity then typically settles into unphysiological rates. To address these issues, we derive a framework for determining the existence and stability of fixed points of the expected conditional intensity function (CIF) for general PP-GLMs. Specifically, in nonlinear Hawkes PP-GLMs, the CIF is expressed as a function of the previous spike history and exogenous inputs. We use a mean-field quasi-renewal (QR) approximation that decomposes spike history effects into the contribution of the last spike and an average of the CIF over all spike histories prior to the last spike. Fixed points for stationary rates are derived as self-consistent solutions of integral equations. Bifurcation analysis and the number of fixed points predict that the original models can show stable, divergent, and metastable (fragile) dynamics. For fragile models, fluctuations of the single-neuron dynamics predict expected divergence times after which rates approach unphysiologically high values. This metric can be used to estimate the probability of rates to remain physiological for given time periods, e.g., for simulation purposes. We demonstrate the use of the stability framework using simulated single-neuron examples and neurophysiological recordings. Finally, we show how to adapt PP-GLM estimation procedures to guarantee model stability. Overall, our results provide a

  15. STAKEHOLDER INVOLVEMENT IN THE HEALTH TECHNOLOGY ASSESSMENT PROCESS IN LATIN AMERICA.

    Science.gov (United States)

    Pichon-Riviere, Andres; Soto, Natalie; Augustovski, Federico; Sampietro-Colom, Laura

    2018-06-11

    Latin American countries are taking important steps to expand and strengthen universal health coverage, and health technology assessment (HTA) has an increasingly prominent role in this process. Participation of all relevant stakeholders has become a priority in this effort. Key issues in this area were discussed during the 2017 Latin American Health Technology Assessment International (HTAi) Policy Forum. The Forum included forty-one participants from Latin American HTA agencies; public, social security, and private insurance sectors; and the pharmaceutical and medical device industry. A background paper and presentations by invited experts and Forum members supported discussions. This study presents a summary of these discussions. Stakeholder involvement in HTA remains inconsistently implemented in the region and few countries have established formal processes. Participants agreed that stakeholder involvement is key to improve the HTA process, but the form and timing of such improvements must be adapted to local contexts. The legitimization of both HTA and decision-making processes was identified as one of the main reasons to promote stakeholder involvement; but to be successful, the entire system of assessment and decision making must be properly staffed and organized, and certain basic conditions must be met, including transparency in the HTA process and a clear link between HTA and decision making. Participants suggested a need for establishing clear rules of participation in HTA that would protect HTA producers and decision makers from potentially distorting external influences. Such rules and mechanisms could help foster trust and credibility among stakeholders, supporting actual involvement in HTA processes.

  16. Nonlinear Decoupling Control With ANFIS-Based Unmodeled Dynamics Compensation for a Class of Complex Industrial Processes.

    Science.gov (United States)

    Zhang, Yajun; Chai, Tianyou; Wang, Hong; Wang, Dianhui; Chen, Xinkai

    2018-06-01

    Complex industrial processes are multivariable and generally exhibit strong coupling among their control loops with heavy nonlinear nature. These make it very difficult to obtain an accurate model. As a result, the conventional and data-driven control methods are difficult to apply. Using a twin-tank level control system as an example, a novel multivariable decoupling control algorithm with adaptive neural-fuzzy inference system (ANFIS)-based unmodeled dynamics (UD) compensation is proposed in this paper for a class of complex industrial processes. At first, a nonlinear multivariable decoupling controller with UD compensation is introduced. Different from the existing methods, the decomposition estimation algorithm using ANFIS is employed to estimate the UD, and the desired estimating and decoupling control effects are achieved. Second, the proposed method does not require the complicated switching mechanism which has been commonly used in the literature. This significantly simplifies the obtained decoupling algorithm and its realization. Third, based on some new lemmas and theorems, the conditions on the stability and convergence of the closed-loop system are analyzed to show the uniform boundedness of all the variables. This is then followed by the summary on experimental tests on a heavily coupled nonlinear twin-tank system that demonstrates the effectiveness and the practicability of the proposed method.

  17. RESEARCH OF LINEAR AND NONLINEAR PROCESSES AT FEMTOSECOND LASER RADIATION PROPAGATION IN THE MEDIUM SIMULATING THE HUMAN EYE VITREOUS

    Directory of Open Access Journals (Sweden)

    P. Y. Rogov

    2015-09-01

    Full Text Available The paper deals with mathematical model of linear and nonlinear processes occurring at the propagation of femtosecond laser pulses in the vitreous of the human eye. Methods of computing modeling are applied for the nonlinear spectral equation solution describing the dynamics of a two-dimensional TE-polarized radiation in a homogeneous isotropic medium with cubic fast-response nonlinearity without the usage of slowly varying envelope approximation. Environments close to the optical media parameters of the eye were used for the simulation. The model of femtosecond radiation propagation takes into account the process dynamics for dispersion broadening of pulses in time and the occurence of the self-focusing near the retina when passing through the vitreous body of the eye. Dependence between the pulse duration on the retina has been revealed and the duration of the input pulse and the values of power density at which there is self-focusing have been found. It is shown that the main mechanism of radiation damage with the use of titanium-sapphire laser is photoionization. The results coincide with those obtained by the other scientists, and are usable for creation Russian laser safety standards for femtosecond laser systems.

  18. Oscillating patterns in image processing and nonlinear evolution equations the fifteenth Dean Jacqueline B. Lewis memorial lectures

    CERN Document Server

    Meyer, Yves

    2001-01-01

    Image compression, the Navier-Stokes equations, and detection of gravitational waves are three seemingly unrelated scientific problems that, remarkably, can be studied from one perspective. The notion that unifies the three problems is that of "oscillating patterns", which are present in many natural images, help to explain nonlinear equations, and are pivotal in studying chirps and frequency-modulated signals. The first chapter of this book considers image processing, more precisely algorithms of image compression and denoising. This research is motivated in particular by the new standard for compression of still images known as JPEG-2000. The second chapter has new results on the Navier-Stokes and other nonlinear evolution equations. Frequency-modulated signals and their use in the detection of gravitational waves are covered in the final chapter. In the book, the author describes both what the oscillating patterns are and the mathematics necessary for their analysis. It turns out that this mathematics invo...

  19. A voice from the high wire: Public involvement in a co-operative siting process

    International Nuclear Information System (INIS)

    Oates, D.J.L.

    1995-01-01

    The author is a public consultation and communications consultant to the Siting Task Force (STF), Low level Radioactive Waste Management. The STF is a Canadian government-appointed yet independent body implementing a voluntary, co-operative siting process for a long term storage or disposal facility for 1 million cubic metres of LLRW. The presentation will document the experiences of and lessons learned by the author during her role developing and implementing a public involvement program for the process. The Co-operative Siting Process is a new approach to siting controversial facilities. It is based on the belief that communities should accept such a facility in their backyard and not be forced against their will on technical or political grounds. A formal 'ground rules-up-front' process was developed and is now being carried out, with completion slated for April, 1995. Putting these rules and theories into practice has resulted in significant changes being made to the work plan for technical activities, and in a sober second look at the intricacies involved in planning and carrying out a thorough and efficient public involvement program that remain practical and cost-effective. There is a delicate balancing act between meaningful public participation that lays the foundation for trust, confidence and consensus, and public involvement that can result in the process being side-tracked and legitimate solutions and technical activities becoming mired in political and personal agendas

  20. tgp: An R Package for Bayesian Nonstationary, Semiparametric Nonlinear Regression and Design by Treed Gaussian Process Models

    Directory of Open Access Journals (Sweden)

    Robert B. Gramacy

    2007-06-01

    Full Text Available The tgp package for R is a tool for fully Bayesian nonstationary, semiparametric nonlinear regression and design by treed Gaussian processes with jumps to the limiting linear model. Special cases also implemented include Bayesian linear models, linear CART, stationary separable and isotropic Gaussian processes. In addition to inference and posterior prediction, the package supports the (sequential design of experiments under these models paired with several objective criteria. 1-d and 2-d plotting, with higher dimension projection and slice capabilities, and tree drawing functions (requiring maptree and combinat packages, are also provided for visualization of tgp objects.

  1. Differential behavior of amino-imino constitutional isomers in nonlinear optical processes.

    Science.gov (United States)

    Latorre, Sonia; Moreira, Ibério de P R; Villacampa, Belén; Julià, Lluís; Velasco, Dolores; Bofill, Josep Maria; López-Calahorra, Francisco

    2010-03-15

    A detailed study of the "blocked" amino-imino tautomers derived from N-acridine-substituted 2-aminobenzothiazole--and their effect on the nonlinear optical response--is presented. The synthesis, characterization, and nonlinear optical properties of these frozen tautomers, namely, N-methyl-N-(2-nitroacridin-6-yl)-2-aminobenzothia-zole and 3-methyl-N-(7-nitroacridin-3-yl)-2-iminobenzothiazole, are reported. A theoretical model based on valence-bond theory is also proposed and used to analyze the effects of the nuclear configuration corresponding to each frozen tautomer structure. In the present case, the aromatic form and the allylic-anion-like system of the -N-C-N- group inherent to each isomer are crucial for understanding and analyzing the different responses of each "blocked" tautomer.

  2. Early print-tuned ERP response with minimal involvement of linguistic processing in Japanese Hiragana strings.

    Science.gov (United States)

    Okumura, Yasuko; Kasai, Tetsuko; Murohashi, Harumitsu

    2014-04-16

    The act of reading leads to the development of specific neural responses for print, the most frequently reported of which is the left occipitotemporal N170 component of event-related potentials. However, it remains unclear whether this electrophysiological response solely involves print-tuned neural activities. The present study examined an early print-tuned event-related potential response with minimal involvement of linguistic processing in a nonalphabetic language. Japanese Hiragana words, nonwords, and alphanumeric symbol strings were presented rapidly and the task was to detect the change in color of a fixation cross to restrict linguistic processing. As a result, Hiragana words and nonwords elicited a larger posterior N1 than alphanumeric symbol strings bilaterally, irrespective of intercharacter spacing. The fact that this N1 was enhanced specifically for rapidly presented Hiragana strings suggests the existence of print-tuned neural processes that are relatively independent of the influence of linguistic processing.

  3. Quasistatic thermal and nonlinear processes of photoconversion of high-density optical radiation by multilayer structures

    Directory of Open Access Journals (Sweden)

    Blank Arkadiy

    2017-01-01

    Full Text Available The results of the systematic experimental analysis of the thermal nonlinear electro-optic properties of photoelectric converters with silicon vertical cells in comparison with solar elements and elements on the basis of In/Ga/As are presented. The parameters of the linear and quadratic approximations for the investigated dependences are determined, that allows constructing a scalable analytic model of the converter with a given type of the working elements switching.

  4. Double-resonant processes in x.sup.20.sup. nonlinear periodic media

    Czech Academy of Sciences Publication Activity Database

    Konotop, V. V.; Kuzmiak, Vladimír

    2000-01-01

    Roč. 17, č. 11 (2000), s. 1874-1883 ISSN 0740-3224 Grant - others:Fundo European de Desenvolvimento Regional and Program PRAXIS XXI(PT) PRAXIS/2/2.1/FIS/176/94 Institutional research plan: CEZ:AV0Z2067918 Keywords : nonlinear media * electromagnetic wave propagation Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 1.943, year: 2000

  5. Laboratory investigation of nonlinear flow characteristics in rough fractures during shear process

    Science.gov (United States)

    Rong, Guan; Yang, Jie; Cheng, Long; Zhou, Chuangbing

    2016-10-01

    To understand the influence of shear behavior on the transporting properties of fluid through a single fracture, splitting fractures were made in the laboratory and shear flow tests were carried out under constant normal load conditions. The applied normal stress is in the range of 0.5-3.0 MPa. Before the physical test, the fracture's morphology is measured for identification of the roughness. At each shear step, we performed 5-8 high precise hydraulic tests with different hydraulic gradient. The relationship between pressure gradient and volume flow rate demonstrates to be nonlinear and fits very well with Forchheimer's and Izbash's laws. The linear and nonlinear coefficients in Forchheimer's law are quite sensitive to shear deformation (closure or dilation), experienced 1-2 and 1-3 orders of magnitude reduction during shear, respectively. An empirical equation is proposed to quantify the relationship between linear coefficient and nonlinear coefficient based on the experimental observations. The two coefficients in Izbash's law are quantified. The m value is in the range between 1.06 and 1.41 and the λ value experiences a reduction of 1-2 orders of magnitude during shear. In addition, the studied critical Reynolds number exhibits a decreasing and increasing variation corresponding to shear contraction and shear dilation of rock fracture. For all the cases in this study, the critical Reynolds number ranges between 1.5 and 13.0.

  6. TRAINING DURING ISO 9001 IMPLEMENTATION AND WORKERS INVOLVEMENT INTO THE QUALITY MANAGEMENT PROCESS IN MONTENEGRO

    Directory of Open Access Journals (Sweden)

    Marc-Arthur Diaye

    2009-03-01

    Full Text Available According to several researchers, workers involvement into the implementation of a quality system in a firm is a key of its success. Since training can improve workers involvement during the implementation of a quality system in a firm, we try in this paper to evaluate quantitatively in the case of Montenegro, the impact of training of workers' involvement. Using an original data set about two leading firms from Montenegro, we show that the coefficient associated with the training variable is on average about -1.44 and is significant at a level of 1%. That is workers who are not trained during the ISO 9001 implementation are strongly less involved into the quality management process of their firms.

  7. Tightening the Purchasing Process: Superintendents Get More Involved in Buying Policies

    Science.gov (United States)

    Rivero, Victor

    2009-01-01

    Over the last 18 months, school district purchasing offices across the country have been tightening the reins like never before while more top-level administrators get involved in the budget process. "When the economy really hit the skids, states got hit hard, so a lot of school districts were forced to make severe budget cuts," says John Musso,…

  8. Links between social information processing in middle childhood and involvement in bullying. [IF 0.95

    NARCIS (Netherlands)

    Camodeca, M.; Goossens, F.A.; Schuengel, C.; Meerum Terwogt, M.

    2003-01-01

    The aim of this study was to investigate the way in which bullies, victims, bully/victims, and those not involved process social information. A peer nomination measure of bullying and victimization was administered twice over an interval of one year. The sample consisted of 236 (126 girls and 110

  9. Reflections on Practical Approaches to Involving Children and Young People in the Data Analysis Process

    Science.gov (United States)

    Coad, Jane; Evans, Ruth

    2008-01-01

    This article reflects on key methodological issues emerging from children and young people's involvement in data analysis processes. We outline a pragmatic framework illustrating different approaches to engaging children, using two case studies of children's experiences of participating in data analysis. The article highlights methods of…

  10. Perceptions of legally mandated public involvement processes in the U.S. Forest Service

    Science.gov (United States)

    S. Andrew Predmore; Marc J. Stern; Michael J. Mortimer; David N. Seesholtz

    2011-01-01

    Results from an agency-wide survey of U.S. Forest Service personnel indicate that respondents in our sample engage in National Environmental Policy Act (NEPA) public involvement processes primarily to accomplish two goals. The most commonly supported goal was to inform and disclose as mandated by the act. The other goal reflected interests in managing agency...

  11. ADHD Coaching with College Students: Exploring the Processes Involved in Motivation and Goal Completion

    Science.gov (United States)

    Prevatt, Frances; Smith, Shannon M.; Diers, Sarah; Marshall, Diana; Coleman, Jennifer; Valler, Emilee; Miller, Nathan

    2017-01-01

    College students with attention-deficit/hyperactivity disorder (ADHD) often experience increased academic difficulties, which can negatively impact graduation rates, employment, self-esteem, and mental health. ADHD coaching assists students with ADHD to reduce such difficulties. The present study evaluated the processes involved in ADHD coaching…

  12. Mobility of persons who are blind: How the attentional processes and working memory are involved?

    OpenAIRE

    PIGEON, Caroline; MARIN-LAMELLET, Claude

    2015-01-01

    Although navigation without vision seems to strongly mobilize the attentional processes and the working memory, few studies seem to be conducted about the link between these processes and the mobility of people who are blind. The main aim of this PhD work is to consider the attentional and working memory capacities of people who are blind and investigate the attentional processes involved during the navigation activity. In the first part of this PhD work, blind participants (early and late) p...

  13. Cochlear Implant: the complexity involved in the decision making process by the family

    Directory of Open Access Journals (Sweden)

    Sheila de Souza Vieira

    2014-06-01

    Full Text Available OBJECTIVE: to understand the meanings the family attributes to the phases of the decision-making process on a cochlear implant for their child.METHOD: qualitative research, using Symbolic Interactionism and Grounded Theory as the theoretical and methodological frameworks, respectively. Data collection instrument: semistructured interview. Nine families participated in the study (32 participants.RESULTS: knowledge deficit, difficulties to contextualize benefits and risks and fear are some factors that make this process difficult. Experiences deriving from interactions with health professionals, other cochlear implant users and their relatives strengthen decision making in favor of the implant.CONCLUSION: deciding on whether or not to have the implant involves a complex process, in which the family needs to weigh gains and losses, experience feelings of accountability and guilt, besides overcoming the risk aversion. Hence, this demands cautious preparation and knowledge from the professionals involved in this intervention.

  14. Cochlear Implant: the complexity involved in the decision making process by the family.

    Science.gov (United States)

    Vieira, Sheila de Souza; Bevilacqua, Maria Cecília; Ferreira, Noeli Marchioro Liston Andrade; Dupas, Giselle

    2014-01-01

    to understand the meanings the family attributes to the phases of the decision-making process on a cochlear implant for their child. qualitative research, using Symbolic Interactionism and Grounded Theory as the theoretical and methodological frameworks, respectively. Data collection instrument: semistructured interview. Nine families participated in the study (32 participants). knowledge deficit, difficulties to contextualize benefits and risks and fear are some factors that make this process difficult. Experiences deriving from interactions with health professionals, other cochlear implant users and their relatives strengthen decision making in favor of the implant. deciding on whether or not to have the implant involves a complex process, in which the family needs to weigh gains and losses, experience feelings of accountability and guilt, besides overcoming the risk aversion. Hence, this demands cautious preparation and knowledge from the professionals involved in this intervention.

  15. Cochlear Implant: the complexity involved in the decision making process by the family1

    Science.gov (United States)

    Vieira, Sheila de Souza; Bevilacqua, Maria Cecília; Ferreira, Noeli Marchioro Liston Andrade; Dupas, Giselle

    2014-01-01

    Objective to understand the meanings the family attributes to the phases of the decision-making process on a cochlear implant for their child. Method qualitative research, using Symbolic Interactionism and Grounded Theory as the theoretical and methodological frameworks, respectively. Data collection instrument: semistructured interview. Nine families participated in the study (32 participants). Results knowledge deficit, difficulties to contextualize benefits and risks and fear are some factors that make this process difficult. Experiences deriving from interactions with health professionals, other cochlear implant users and their relatives strengthen decision making in favor of the implant. Conclusion deciding on whether or not to have the implant involves a complex process, in which the family needs to weigh gains and losses, experience feelings of accountability and guilt, besides overcoming the risk aversion. Hence, this demands cautious preparation and knowledge from the professionals involved in this intervention. PMID:25029052

  16. Limitations of Feedback, Feedforward and IMC Controller for a First Order Non-Linear Process with Dead Time

    Directory of Open Access Journals (Sweden)

    Maruthai Suresh

    2010-10-01

    Full Text Available A nonlinear process, the heat exchanger whose parameters vary with respect to the process variable, is considered. The time constant and gain of the chosen process vary as a function of temperature. The limitations of the conventional feedback controller tuned using Ziegler-Nichols settings for the chosen process are brought out. The servo and regulatory responses through simulation and experimentation for various magnitudes of set-point changes and load changes at various operating points with the controller tuned only at a chosen nominal operating point are obtained and analyzed. Regulatory responses for output load changes are studied. The efficiency of feedforward controller and the effects of modeling error have been brought out. An IMC based system is presented to understand clearly how variations of system parameters affect the performance of the controller. The present work illustrates the effectiveness of Feedforward and IMC controller.

  17. Final report on the public involvement process phase 1, Monitored Retrievable Storage Facility Feasibility Study

    International Nuclear Information System (INIS)

    Moore, L.; Shanteau, C.

    1992-12-01

    This report summarizes the pubic involvement component of Phase 1 of the Monitored Retrievable Storage Facility (NM) Feasibility Study in San Juan County, Utah. Part of this summary includes background information on the federal effort to locate a voluntary site for temporary storage of nuclear waste, how San Juan County came to be involved, and a profile of the county. The heart of the report, however, summarizes the activities within the public involvement process, and the issues raised in those various forums. The authors have made every effort to reflect accurately and thoroughly all the concerns and suggestions expressed to us during the five month process. We hope that this report itself is a successful model of partnership with the citizens of the county -- the same kind of partnership the county is seeking to develop with its constituents. Finally, this report offers some suggestions to both county officials and residents alike. These suggestions concern how decision-making about the county's future can be done by a partnership of informed citizens and listening decision-makers. In the Appendix are materials relating to the public involvement process in San Juan County

  18. Final report on the public involvement process phase 1, Monitored Retrievable Storage Facility Feasibility Study

    Energy Technology Data Exchange (ETDEWEB)

    Moore, L.; Shanteau, C.

    1992-12-01

    This report summarizes the pubic involvement component of Phase 1 of the Monitored Retrievable Storage Facility (NM) Feasibility Study in San Juan County, Utah. Part of this summary includes background information on the federal effort to locate a voluntary site for temporary storage of nuclear waste, how San Juan County came to be involved, and a profile of the county. The heart of the report, however, summarizes the activities within the public involvement process, and the issues raised in those various forums. The authors have made every effort to reflect accurately and thoroughly all the concerns and suggestions expressed to us during the five month process. We hope that this report itself is a successful model of partnership with the citizens of the county -- the same kind of partnership the county is seeking to develop with its constituents. Finally, this report offers some suggestions to both county officials and residents alike. These suggestions concern how decision-making about the county's future can be done by a partnership of informed citizens and listening decision-makers. In the Appendix are materials relating to the public involvement process in San Juan County.

  19. Final report on the public involvement process phase 1, Monitored Retrievable Storage Facility Feasibility Study

    Energy Technology Data Exchange (ETDEWEB)

    Moore, L.; Shanteau, C.

    1992-12-01

    This report summarizes the pubic involvement component of Phase 1 of the Monitored Retrievable Storage Facility (NM) Feasibility Study in San Juan County, Utah. Part of this summary includes background information on the federal effort to locate a voluntary site for temporary storage of nuclear waste, how San Juan County came to be involved, and a profile of the county. The heart of the report, however, summarizes the activities within the public involvement process, and the issues raised in those various forums. The authors have made every effort to reflect accurately and thoroughly all the concerns and suggestions expressed to us during the five month process. We hope that this report itself is a successful model of partnership with the citizens of the county -- the same kind of partnership the county is seeking to develop with its constituents. Finally, this report offers some suggestions to both county officials and residents alike. These suggestions concern how decision-making about the county`s future can be done by a partnership of informed citizens and listening decision-makers. In the Appendix are materials relating to the public involvement process in San Juan County.

  20. Adaptive PI Controller for a Nonlinear System

    Directory of Open Access Journals (Sweden)

    D. Rathikarani

    2009-10-01

    Full Text Available Most of the industrial processes are inherently nonlinear in their behaviour. Designs of controllers for these nonlinear processes are difficult, as they do not follow superposition theorem. Adaptive controller can change its behaviour in response to changes in the dynamics of the process and disturbances. Hence adaptive controller can be used to control nonlinear processes. Direct Model Reference Adaptive Control is a technique, in which a reference model involving the desired performances is specified. In the present work, a DMRAC is designed and implemented to achieve satisfactory control of a nonlinear system in all its local linear operating regions. The closed loop system is made BIBO stable by proper control techniques. The controller is designed through simulation in Matlab platform and is validated in real time by conducting experiments on the laboratory Air Flow Control System using the dSPACE interface.

  1. Structure formation in turbulent plasmas - test of nonlinear processes in plasma experiments

    International Nuclear Information System (INIS)

    Itoh, S.-I.; Yagi, Masatoshi; Inagaki, Shigeru

    2009-01-01

    Full text: Recent developments in plasma physics, either in the fusion research in a new era of ITER, or in space and in astro-physics, the world-wide and focused research has been developed on the subject of structural formation in turbulent plasma being associated with electro-magnetic field formation. Keys for the progress were a change of the physics view from the 'linear, local and deterministic' picture to the description based on 'nonlinear instability, nonlocal interaction and probabilistic excitation' for the turbulent state, and the integration of the theory-simulation-experiment. In this presentation, we first briefly summarize the theory of microscopic turbulence and mesoscale fluctuations and selection rules. In addition, the statistical formation of large-scale structure/deformation by turbulence is addressed. Then, the experimental measurements of the mesoscale structures (e.g., zonal flows, zonal fields, streamer and transport interface) and of the nonlinear interactions among them in turbulent plasmas are reported. Confirmations by, and new challenges from, the experiments are overviewed. Work supported by the Grant-in-Aid for Specially-Promoted Research (16002005). (author)

  2. Nonlinear model-based control of the Czochralski process III: Proper choice of manipulated variables and controller parameter scheduling

    Science.gov (United States)

    Neubert, M.; Winkler, J.

    2012-12-01

    This contribution continues an article series [1,2] about the nonlinear model-based control of the Czochralski crystal growth process. The key idea of the presented approach is to use a sophisticated combination of nonlinear model-based and conventional (linear) PI controllers for tracking of both, crystal radius and growth rate. Using heater power and pulling speed as manipulated variables several controller structures are possible. The present part tries to systematize the properties of the materials to be grown in order to get unambiguous decision criteria for a most profitable choice of the controller structure. For this purpose a material specific constant M called interface mobility and a more process specific constant S called system response number are introduced. While the first one summarizes important material properties like thermal conductivity and latent heat the latter one characterizes the process by evaluating the average axial thermal gradients at the phase boundary and the actual growth rate at which the crystal is grown. Furthermore these characteristic numbers are useful for establishing a scheduling strategy for the PI controller parameters in order to improve the controller performance. Finally, both numbers give a better understanding of the general thermal system dynamics of the Czochralski technique.

  3. Nonlinear dynamics of semiconductors in strong THz electric fields

    DEFF Research Database (Denmark)

    Tarekegne, Abebe Tilahun

    In this thesis, we investigate nonlinear interactions of an intense terahertz (THz) field with semiconductors, in particular the technologically relevant materials silicon and silicon carbide. We reveal the time-resolved dynamics of the nonlinear processes by pump-probe experiments that involve...

  4. Functional brain imaging study on brain processes involved in visual awareness

    International Nuclear Information System (INIS)

    Kobayashi, Tetsuo; Futakawa, Hiroyuki; Tokita, Shohko; Jung, Jiuk

    2003-01-01

    Recently, there has been great interest in visual awareness because it is thought that it may provide valuable information in understanding aspects of consciousness. An important but still controversial issue is what region in the brain is involved in visual awareness. When viewing ambiguous figures, observers can be aware of only one of multiple competing percepts at any given moment, but experience spontaneous alternations among the percepts over time. This phenomenon is known as multistable perceptions and thought to be essential in understanding the brain processes involved in visual awareness. We used functional magnetic resonance imaging to investigate the brain activities associated with multistable perceptions. Two separate experiments were performed based on two different multistable phenomena known as binocular rivalry and perceptions of ambiguous figures. Significant differential activations in the parietal and prefrontal areas were commonly observed under multistable conditions compared to monostable control conditions in the two separate experiments. These findings suggest that neural processes in the parietal and prefrontal areas may be involved in perceptual alternations in situations involving multistable phenomena. (author)

  5. Prediction of minimum temperatures in an alpine region by linear and non-linear post-processing of meteorological models

    Directory of Open Access Journals (Sweden)

    R. Barbiero

    2007-05-01

    Full Text Available Model Output Statistics (MOS refers to a method of post-processing the direct outputs of numerical weather prediction (NWP models in order to reduce the biases introduced by a coarse horizontal resolution. This technique is especially useful in orographically complex regions, where large differences can be found between the NWP elevation model and the true orography. This study carries out a comparison of linear and non-linear MOS methods, aimed at the prediction of minimum temperatures in a fruit-growing region of the Italian Alps, based on the output of two different NWPs (ECMWF T511–L60 and LAMI-3. Temperature, of course, is a particularly important NWP output; among other roles it drives the local frost forecast, which is of great interest to agriculture. The mechanisms of cold air drainage, a distinctive aspect of mountain environments, are often unsatisfactorily captured by global circulation models. The simplest post-processing technique applied in this work was a correction for the mean bias, assessed at individual model grid points. We also implemented a multivariate linear regression on the output at the grid points surrounding the target area, and two non-linear models based on machine learning techniques: Neural Networks and Random Forest. We compare the performance of all these techniques on four different NWP data sets. Downscaling the temperatures clearly improved the temperature forecasts with respect to the raw NWP output, and also with respect to the basic mean bias correction. Multivariate methods generally yielded better results, but the advantage of using non-linear algorithms was small if not negligible. RF, the best performing method, was implemented on ECMWF prognostic output at 06:00 UTC over the 9 grid points surrounding the target area. Mean absolute errors in the prediction of 2 m temperature at 06:00 UTC were approximately 1.2°C, close to the natural variability inside the area itself.

  6. Diversity for design: A framework for involving neurodiverse children in the technology design process

    OpenAIRE

    Benton, L.; Vasalou, A.; Khaled, R.; Johnson, H.; Gooch, D.

    2014-01-01

    The neurodiversity movement seeks to positively reframe certain neurological conditions, such as autism spectrum disorders (ASD) and dyslexia, by concentrating on their strengths. In recent years, neurodiverse children have increasingly been involved in the technology design process, but the design approaches adopted have focused mostly on overcoming difficulties of working with these children, leaving their strengths untapped. We present a new participatory design (PD) framework, Diversity f...

  7. Diversity for design : a framework for involving neurodiverse children in the technology design process

    OpenAIRE

    Benton, Laura; Vasalou, Asimina; Khaled, Rilla; Johnson, Hilary; Gooch, Daniel

    2014-01-01

    The neurodiversity movement seeks to positively reframe certain neurological conditions, such as autism spectrum disorders (ASD) and dyslexia, by concentrating on their strengths. In recent years, neurodiverse children have increasingly been involved in the technology design process, but the design approaches adopted have focused mostly on overcoming difficulties of working with these children, leaving their strengths untapped. We present a new participatory design (PD) framework, Diversity f...

  8. Domain general sequence operations contribute to pre-SMA involvement in visuo-spatial processing

    Directory of Open Access Journals (Sweden)

    E. Charles eLeek

    2016-01-01

    Full Text Available This study used 3T MRI to elucidate the functional role of supplementary motor area (SMA in relation to visuo-spatial processing. A localizer task contrasting sequential number subtraction and repetitive button pressing was used to functionally delineate non-motor sequence processing in pre-SMA, and activity in SMA-proper associated with motor sequencing. Patterns of BOLD responses in these regions were then contrasted to those from two tasks of visuo-spatial processing. In one task participants performed mental rotation in which recognition memory judgments were made to previously memorized 2D novel patterns across image-plane rotations. The other task involved abstract grid navigation in which observers computed a series of imagined location shifts in response to directional (arrow cues around a mental grid. The results showed overlapping activation in pre-SMA for sequential subtraction and both visuo-spatial tasks. These results suggest that visuo-spatial processing is supported by non-motor sequence operations that involve pre-SMA. More broadly, these data further highlight the functional heterogeneity of pre-SMA, and show that its role extends to processes beyond the planning and online control of movement.

  9. The difficulties experienced by nurses and healthcare staff involved in the process of breaking bad news.

    Science.gov (United States)

    Warnock, Clare; Buchanan, Jean; Tod, Angela Mary

    2017-07-01

    The aim of this study was to explore the difficulties experienced by nurses and healthcare professionals when engaging in the process of breaking bad news. The challenges faced by staff when breaking bad news have previously been researched in relation to particular settings or participants. This study involved staff from diverse settings and roles to develop broader insights into the range of difficulties experienced in clinical practice. The study used a descriptive survey design involving self-reported written accounts and framework analysis. Data were collected using a structured questionnaire containing a free text section that asked participants to describe a difficult experience they had encountered when involved in the process of breaking bad news. Data were collected from healthcare staff from hospital, community, hospice and care home settings attending training days on breaking bad news between April 2011 and April 2014. Multiple inter-related factors presented challenges to staff engaging in activities associated with breaking bad news. Traditional subjects such as diagnostic and treatment information were described but additional topics were identified such as the impact of illness and care at the end of life. A descriptive framework was developed that summarizes the factors that contribute to creating difficult experiences for staff when breaking bad news. The framework provides insights into the scope of the challenges faced by staff when they engage in the process of breaking bad news. This provides the foundation for developing interventions to support staff that more closely matches their experiences in clinical practice. © 2017 John Wiley & Sons Ltd.

  10. Scanning Electron Microscope Calibration Using a Multi-Image Non-Linear Minimization Process

    Science.gov (United States)

    Cui, Le; Marchand, Éric

    2015-04-01

    A scanning electron microscope (SEM) calibrating approach based on non-linear minimization procedure is presented in this article. A part of this article has been published in IEEE International Conference on Robotics and Automation (ICRA), 2014. . Both the intrinsic parameters and the extrinsic parameters estimations are achieved simultaneously by minimizing the registration error. The proposed approach considers multi-images of a multi-scale calibration pattern view from different positions and orientations. Since the projection geometry of the scanning electron microscope is different from that of a classical optical sensor, the perspective projection model and the parallel projection model are considered and compared with distortion models. Experiments are realized by varying the position and the orientation of a multi-scale chessboard calibration pattern from 300× to 10,000×. The experimental results show the efficiency and the accuracy of this approach.

  11. Effects of noninstantaneous nonlinear processes on photon-pair generation by spontaneous four-wave mixing

    DEFF Research Database (Denmark)

    Koefoed, Jacob Gade; Christensen, Jesper Bjerge; Rottwitt, Karsten

    2017-01-01

    We present a general model, based on a Hamiltonian approach, for the joint quantum state of photon pairs generated through pulsed spontaneous four-wave mixing, including nonlinear phase modulation and a finite material response time. For the case of a silica fiber, it is found that the pair......-production rate depends weakly on the waveguide temperature, due to higher-order Raman scattering events, and more strongly on pump-pair frequency detuning. From the analytical model, a numerical scheme is derived, based on the well-known split-step method. This scheme allows computation of joint states where......-dependent change in quantum-mechanical purity may be observed in silica. This shows that Raman scattering not only introduces noise, but can also drastically change the spectral correlations in photon pairs when pumped with short pulses....

  12. Einstein-Podolsky-Rosen entanglement via nonlinear processes enhanced by electromagnetically induced transparency

    International Nuclear Information System (INIS)

    Cheng Guangling; Hu Xiangming; Zhong Wenxue

    2009-01-01

    We show that Einstein-Podolsky-Rosen (EPR) light entanglement is obtainable via the resonant nonlinear interactions enhanced by electromagnetically induced transparency. A three-level system is used as a unified model, where two metastable states are coupled to each other via microwave, or Raman, or two-photon transition, and the upper metastable state is coupled to the excited state. A pair of inner sidebands is amplified as optical cavity modes via the transition from the excited state to the other metastable state. The analysis is presented by using the dressed-atom squeezed-transformed-mode approach. For a proper ratio of the amplitudes of the applied fields, the sum of the variances for two EPR-like operators approaches zero, which corresponds to EPR entanglement.

  13. Diagnostic tool for structural health monitoring: effect of material nonlinearity and vibro-impact process

    Science.gov (United States)

    Hiwarkar, V. R.; Babitsky, V. I.; Silberschmidt, V. V.

    2013-07-01

    Numerous techniques are available for monitoring structural health. Most of these techniques are expensive and time-consuming. In this paper, vibration-based techniques are explored together with their use as diagnostic tools for structural health monitoring. Finite-element simulations are used to study the effect of material nonlinearity on dynamics of a cracked bar. Additionally, several experiments are performed to study the effect of vibro-impact behavior of crack on its dynamics. It was observed that a change in the natural frequency of the cracked bar due to crack-tip plasticity and vibro-impact behavior linked to interaction of crack faces, obtained from experiments, led to generation of higher harmonics; this can be used as a diagnostic tool for structural health monitoring.

  14. Involving the stakeholders in the curriculum process: a recipe for success?

    Science.gov (United States)

    Keogh, Johannes J; Fourie, Willem J; Watson, Sheona; Gay, H

    2010-01-01

    The Department of Nursing and Health Studies at the Manukau Institute of Technology (MIT) in Auckland, New Zealand, decided to involve stakeholders from the health care sector in developing a new curriculum. After implementing the new curriculum, the process was evaluated using a content analysis as qualitative research design. Seven individual interviews and one Focus group interview were conducted with the stakeholders to determine their experiences during the process. Ethical permission was sought from the MIT ethical committee. The analyses of the collected data enabled the researchers to identify six main categories. The categories were: "Existing Programme", "The need to change", "The curriculum development process", "The stakeholders", "Personnel", and "Ethnic minorities". From the collected data, it was clear that a new curriculum was necessary to enable the graduates to meet the health care needs of the New Zealand population, especially after the primary health care policy was introduced in New Zealand. It was also clear that the curriculum development process could be a painful process for all concerned, but a strong leadership could cement a feeling of "collegiality" between stakeholders and teaching staff. The importance of considering the rights of ethnic minorities is clearly stated in the Treaty of Waitangi, safeguarding the rights of the Maori People, and therefore applied rigorously in the development process. In this project, the collaborative process was very successful, and the stakeholders actually expressed feelings of "Ownership" of the curriculum.

  15. Forms And Methods Of Modern Russian Youth Involvement Into The Electoral Process

    Directory of Open Access Journals (Sweden)

    Aleksey D. Maslov

    2015-03-01

    Full Text Available In the present article authors analyzes forms and methods of modern Russian youth involvement in the electoral process. Involving young people in the electoral process is directly related to the problem of increasing the level of political culture in the society. This article presents the main forms of work to attract young people to participate in elections in our country, according to the Central Election Commission (CEC of Russia, some of the regional election commissions, the Russian Public Opinion Research Center (WCIOM. Authors note that at present there are more than one hundred and sixty legislative acts of the Russian Federation, which reflect certain aspects of the state youth policy. All these measures stimulate the political activity of young people, but in our opinion, that is not enough. The fundamental change in the attitude of young people to politics, to the institution of elections is possible only when young people feel like a real part and the subject of transformation processes in our country. In conclusion authors summarizes, that a fundamental change in the relationship of young people to politics, the institution of elections is possible only, when very young feel a real party and the subject of transformation processes in our country. This is possible only when the state is really and not formally prioritizes youth policy. Young people should have a daily state support for education, starting a business, implementation of acquired skills for a decent fee, starting a family, buying a house, etc.

  16. Stakeholders and public involvement in river management: heterogeneous acceptance of participatory processes among Swiss institutions.

    Science.gov (United States)

    Buletti, Nora; Utz, Stephan; Ejderyan, Olivier; Graefe, Olivier; Lane, Stuart; Reynard, Emmanuel

    2014-05-01

    This research explores participatory processes in the domain of river management in Switzerland. The main objective is to better understand how participatory processes are incorporated into river management practice. Switzerland being a federal state, river management is a cantonal (regional) responsibility, under the supervision (and co-funding) of the State (a Confederation). The federal funding includes the opportunity to fund additional participatory activities to aid river management, not least because the federal authorities consider the involvement of wider stakeholders and the public in decision-making as a means of aiding the progression of projects. This is a particularly important goal in a Swiss setting where direct democracy (the possibility of calling the decision of any level of government into question through a popular vote) means that a reasonable level of project acceptance is a necessary element of project progression. River management in Switzerland now includes both flood protection and river restoration objectives, which has served to increase its controversy: river corridors contain competing interests with different objectives (e.g. ecological enhancement, protection of agricultural land, flood risk reduction). We were asked by the Confederation to evaluate participatory processes it sponsored and one element of this evaluation aimed to develop a typology of stakeholder participation. We conducted interviews with the 26 cantonal officers in charge of river management. These interviews were based upon thematically structured open ended questions, with the responses analyzed qualitatively. We have identified significant divergence in the implementation of participatory processes between the cantons. These appear to be related to two factors: (1) the canton's historical experience of river management; and (2) the methods used to select stakeholders for inclusion in the decisional process. Cantons that refer to guidelines or pre

  17. The interactive alphabet with augmented reality as a form of involving children in educational process

    Directory of Open Access Journals (Sweden)

    Vladimir D. Sekerin

    2017-01-01

    Full Text Available Research objective: to prove the expediency of using technologies with augmented reality in educational process of children in order to increase the level of their involvement and to improve the efficiency of educational process. Materials and methods. The information base of the research was made by scientific publications, information and analytical reviews, periodicals, monographs, information placed in the Internet network, concerning practical application of technologies with augmented reality in educational process, descriptive and comparative methods of analysis form the methodical basis of this research. Results. It is shown that in educational process of children it is expedient to use the modern technological achievements allowing organizing productive interactions and relationship of the students among themselves and with teachers, lecturers. Educational, business, role-playing games, discussions promoting acceleration of acquiring  a new experience and receiving new knowledge are the perspective formats of realizing the educational process. The world of augmented reality has the following properties: combines the real and virtual, interacts in real time mode, and functions in three-dimensional space. The advantages of the Interactive alphabet on the basis of the augmented reality technology are as follows: 1 security of strong emotional responses; 2 the involvement and interactivity promoting steady memorizing; 3 possibilities of interaction with the artificial world by means of gadgets; 4 Digital and offline communication; 5 possibility of carrying out virtual lessons. One of the main features of virtual reality is the feeling of participation and the opportunity to observe everything from the first person. It makes expedient to carry out lessons entirely in the virtual reality. Achievement of full involvement in educational process promotes increase of motivation and progress in knowledge acquisition.  The use of the augmented

  18. Sulfomethylated lignosulfonates as additives in oil recovery processes involving chemical recovery agents

    Energy Technology Data Exchange (ETDEWEB)

    Kalfoglou, G.

    1979-10-30

    A process for producing petroleum from subterranean formations is disclosed wherein production from the formation is obtained by driving a fluid from an injection well to a production well. The process involves injecting via the injection well into the formation an aqueous solution of sulfomethylated lignosulfonate salt as a sacrificial agent to inhibit the deposition of surfactant and/or polymer on the reservoir matrix. The process may best be carried out by injecting the sulfomethylated lignosulfonates into the formation through the injection well mixed with either a polymer, a surfactant solution and/or a micellar dispersion. This mixture would then be followed by a drive fluid such as water to push the chemicals to the production well.

  19. Sulfomethylated lignosulfonates as additives in oil recovery processes involving chemical recovery agents

    Energy Technology Data Exchange (ETDEWEB)

    Kalfoglou, G.

    1981-05-26

    A process for producing petroleum from subterranean formations is disclosed wherein production from the formation is obtained by driving a fluid from an injection well to a production well. The process involves injecting via the injection well into the formation an aqueous solution of sulfomethylated lignosulfonate salt as a sacrificial agent to inhibit the deposition of surfactant and/or polymer on the reservoir matrix. The process may best be carried out by injecting the sulfomethylated lignosulfonates into the formation through the injection well mixed with either a polymer, a surfactant solution and/or a micellar dispersion. This mixture would then be followed by a drive fluid such as water to push the chemicals to the production well.

  20. Monitoring and control of amygdala neurofeedback involves distributed information processing in the human brain.

    Science.gov (United States)

    Paret, Christian; Zähringer, Jenny; Ruf, Matthias; Gerchen, Martin Fungisai; Mall, Stephanie; Hendler, Talma; Schmahl, Christian; Ende, Gabriele

    2018-03-30

    Brain-computer interfaces provide conscious access to neural activity by means of brain-derived feedback ("neurofeedback"). An individual's abilities to monitor and control feedback are two necessary processes for effective neurofeedback therapy, yet their underlying functional neuroanatomy is still being debated. In this study, healthy subjects received visual feedback from their amygdala response to negative pictures. Activation and functional connectivity were analyzed to disentangle the role of brain regions in different processes. Feedback monitoring was mapped to the thalamus, ventromedial prefrontal cortex (vmPFC), ventral striatum (VS), and rostral PFC. The VS responded to feedback corresponding to instructions while rPFC activity differentiated between conditions and predicted amygdala regulation. Control involved the lateral PFC, anterior cingulate, and insula. Monitoring and control activity overlapped in the VS and thalamus. Extending current neural models of neurofeedback, this study introduces monitoring and control of feedback as anatomically dissociated processes, and suggests their important role in voluntary neuromodulation. © 2018 Wiley Periodicals, Inc.

  1. Stake holder involvement in the Canadian review process for uranium production projects in Northern Saskatchewan

    International Nuclear Information System (INIS)

    Underhill, D.

    2004-01-01

    This report describes the Canadian environmental review process for uranium production projects as a case study for the purpose of understanding the nature and value of stakeholder involvement in the management of radiological hazards. While the Canadian review process potentially applies to any development, this case study focuses on the assessment of the uranium projects of northern Saskatchewan conducted during the 1990's. It describes the environmental assessment (EA) conducted in the 1990's for six new uranium facilities (including mines and mills and related tailings disposal sites) planned in northern Saskatchewan. Both the Canadian federal and the Saskatchewan provincial government have extensive environmental review processes that must under law be complete before any major industrial development judged to have potential environmental impacts is undertaken within their respective territories. However, even in those instances where no clear potential environmental impacts are evident, Canadian law mandates 'if public concern about the proposal is such that a public review is desirable, the initiating department shall refer the proposal to the Minister for review by a Panel'. (Wh95) As a stakeholder under law, in both Canada and Saskatchewan, the public plays an important role in the environmental review process. To encourage participation and assist the public in its review the two governments may provide funding (as done in this review) to assist qualified individuals or groups to participant in the review process. The first section of this case study sets the scene. It describes the Saskatchewan uranium mining story, focusing on how the importance of the public stakeholder evolved to become a major component, under law, in the EA process for new uranium mines. This increase in stakeholder involvement opportunities coincided with heightened public concern for the socio-economic impacts of the projects. In the late 1980's both governments were advised by

  2. EMPLOYEE INVOLVEMENT IN A CHANGE PROCESS - A CASE STUDY FOR ROMANIAN ORGANIZATIONS

    Directory of Open Access Journals (Sweden)

    Prediscan Mariana

    2015-07-01

    Full Text Available Innovation, competitive advantage, change are some concepts that should be on every organization's agenda, due to the fact the global market leads to global competition so in order to increase the market share, turnover or profit organizations have to incorporate those concepts in their strategies. The outside environment is very unstable and things are evolving very fast so managers from all levels have to acknowledge the importance of change and to identify as soon as possible several new ideas that should be the subject of different change processes. Openness to organizational change has become a mandatory feature for those organizations that want to survive and adapt to the external pressure, helping them to be efficient. Even if in many cases managers are the initiators of change, this process is very complex and needs support and involvement from all the members of the organization, so the employee's attitude and commitment to change is crucial. In many cases employees have a negative attitude towards change and manifest a strong resistance, due to the fact that they are not consulted and are not involved in the process of the identification for the need of change. Without understanding and knowing very well what it is expected from them, employees are afraid of the unknown and prefer to perform their tasks as they did before. Creating a climate and a culture for change is very important, because like this change will be something normal, continuous and people will feel comfortable with any change initiatives, without being surprised, confused or scared. Even if any change process should improve the current state of the organization, sometimes change efforts fail because the ones that resist change are stronger than the ones supporting change. The purpose of this paper is to analyze how often are Romanian employees involved in the processes of change and how important is the role they play. We have also tried to see the Romanian manager

  3. Involvement of translation and transcription processes into neurophysiological mechanisms of long-term memory reconsolidation.

    Science.gov (United States)

    Kozyrev, S A; Nikitin, V P

    2013-03-01

    We studied the involvement of translation and transcription processes into behavioral and neuronal mechanisms of reconsolidation of the long-term memory of the conditioned taste aversion in edible snails. Injection of cycloheximide (an inhibitor of protein synthesis) to the snails in 48 h after training combined with subsequent reminder and presentation of the conditional stimulus resulted in the development of persistent amnesia and depression of the responses of the defensive behavior command neurons LPl1 and RPl1 to the conditional stimulus. Injection of mRNA synthesis inhibitors actinomycin D or DRB (5,6-dichloro-1-β-D-ribofuranosylbenzimidasole) in 48 h after conditioning with subsequent reminding procedure produced no effects on memory retention and on the responses of the command neurons to the conditional stimulus. The study suggests that the proteins translated from previously synthesized and stored mRNA were involved in the mechanisms of reconsolidation of the memory responsible for conditioned taste aversion.

  4. Relevant Factors in the Process of Socialization, Involvement and Belonging of Descendants in Family Businesses

    Directory of Open Access Journals (Sweden)

    Melquicedec Lozano-Posso

    2016-12-01

    Full Text Available This research works toward the identification of the factors that comprise the process of socialization, involvement and initial belonging of descendants in family businesses and the key relationships between them. By means of a qualitative detailed study of four cases, complemented by a quantitative survey of 274 Colombian family businesses, the authors generate a new model that takes into account both factors explored in previous research as well as others identified in this study. Findings confirm the specific dependency of each stage on the subsequent ones; socialization influences involvement, which in turn influences the belonging of the descendants to the family business, with a strong presence of factors such as knowledge, leadership, mode, timing, and motivation. Those responsible for the orientation of potential successors may examine these findings in order to optimize their preparation efforts and support of family human resources for the continuity of the business.

  5. The insula is not specifically involved in disgust processing: an fMRI study.

    Science.gov (United States)

    Schienle, A; Stark, R; Walter, B; Blecker, C; Ott, U; Kirsch, P; Sammer, G; Vaitl, D

    2002-11-15

    fMRI studies have shown that the perception of facial disgust expressions specifically activates the insula. The present fMRI study investigated whether this structure is also involved in the processing of visual stimuli depicting non-mimic disgust elicitors compared to fear-inducing and neutral scenes. Twelve female subjects were scanned while viewing alternating blocks of 40 disgust-inducing, 40 fear-inducing and 40 affectively neutral pictures, shown for 1.5 s each. Afterwards, affective ratings were assessed. The disgust pictures, rated as highly repulsive, induced activation in the insula, the amygdala, the orbitofrontal and occipito-temporal cortex. Since during the fear condition the insula was also involved, our findings do not fit the idea of the insula as a specific disgust processor.

  6. A quality assurance program for environmental data operations involving waste management processes

    International Nuclear Information System (INIS)

    Johnson, G.L.; Blacker, S.M.

    1990-01-01

    This paper describes the 'core' elements needed in an effective Quality Program for environmental data operations involving nuclear, mixed, or non-nuclear wastes. For each core element, this paper examines the minimum components needed for an effective Quality Program for EDOs, and compares approaches to Quality Programs currently required by the U.S. DOE and the U.S. EPA. The comparison suggests how the Quality Program requirements used at DOE, and defined by NQA-1 and its supplements, and those used by EPA through its QAMS program guidance, may provide a basis for developing a harmonized Quality Program for EDOs involving any waste management processes, nuclear, non-nuclear, or mixed. (orig./DG)

  7. APP processing and the APP-KPI domain involvement in the amyloid cascade.

    Science.gov (United States)

    Menéndez-González, M; Pérez-Pinera, P; Martínez-Rivera, M; Calatayud, M T; Blázquez Menes, B

    2005-01-01

    Alternative APP mRNA splicing can generate isoforms of APP containing a Kunitz protease inhibitor (KPI) domain. KPI is one of the main serine protease inhibitors. Protein and mRNA KPI(+)APP levels are elevated in Alzheimer's disease (AD) brain and are associated with increased amyloid beta deposition. In the last years increasing evidence on multiple points in the amyloid cascade where KPI(+)APP is involved has been accumulated, admitting an outstanding position in the pathogenesis of AD to the KPI domain. This review focuses on the APP processing, the molecular activity of KPI and its physiological and pathological roles and the KPI involvement in the amyloid cascade through the nerve growth factor, the lipoprotein receptor-related protein, the tumor necrosis factor-alpha converting enzyme and the Notch1 protein.

  8. Process development and characterization of centrosymmetric semiorganic nonlinear optical crystal: 4-dimethylaminopyridine potassium chloride

    Science.gov (United States)

    Johnson, J.; Srineevasan, R.; Sivavishnu, D.

    2018-06-01

    Centrosymmetric semiorganic crystal 4-dimethylaminopyridine potassium chloride (4-DMAPKC) has been grown successfully by using slow evaporation solution growth technique. Powder x-ray diffraction shows the 4-DMAPKC crystal has good crystalline nature. Single crystal XRD shows that the grown 4-DMAPKC is cubic crystal system with cell parameters a = 3.09 Å, b = 3.09 Å, c = 3.09 Å. Investigation has been carried out to assign the Vibrational frequencies of the grown crystal by FTIR spectral studies. UVsbnd Visible NIR optical absorption spectral studies in the range of 200-1100 nm shows low absorption in UVsbnd Visible region with lower cutoff wave length at 261 nm and optical band gap energy was found as Eg = 5.52 eV. Optically transmittance spectral shows 4-DMAPKC crystal is very good transparency in UV-Visible NIR region. Thermogravimetry and differential thermal (TG-DTA) analysis were carried out. Dielectric studies of as grown crystal sample exhibit low dielectric constant and loss at higher frequencies and attests the nonlinear optical activity. Micro hardness studies of as grown crystal were discussed. Second harmonic generation (SHG) efficiency of the 4-DMAPKC is 0.69 times as that of KDP.

  9. A new type of EPR experiment using light quanta produced by nonlinear optical process

    International Nuclear Information System (INIS)

    Shih, Y.H.; Alley, C.O.

    1989-01-01

    A pair of correlated light quanta of 532 nm wavelength with the same linear polarization but divergent directions of propagation was produced by non-linear optical parametric down conversion in a crystal of deuterated potassium di-hydrogen phosphate from a 100 ps duration laser pulse of 266 nm wavelength. Each light quantum was converted to a circular polarization state or a linear polarization state (orthogonal) and was reflected by a turning mirror to superpose with the other at a beam splitter to produce a two-quanta superposition state. For coincident detection of the two light quanta at separated detectors, correlations of the Einstein-Podolsky-Rosen type for the polarizations have been observed as predicted by our analysis. In preliminary runs with limited data we have measured a violation of Bell's inequality by three standard deviations. We are planning to extend our experiments to include a truly random delayed choice between two analyser settings at each detector while maintaining a spacelike separation between the detections. (orig.)

  10. A process for integrating public involvement into technical/social programs

    International Nuclear Information System (INIS)

    Wiltshire, S.; Williams, C.

    1994-01-01

    Good technical/social decisions--those that are technically sound and publicly acceptable--result from a planning process that considers consulting the public a basic part of the technical program, as basic as hiring a technical consultant to advise about new ideas in computer modeling. This paper describes a specific process for making public involvement an integral part of decision-making about high-level radioactive waste management, so that important technical, social, environmental, economic, and cultural information and values can be incorporated in a meaningful way in planning and carrying out a high-level waste management program or project. The process for integration must consider: (a) the decision or task for which public interaction is needed; (b) the people who should or will want to participate in the decision or task; (c) the goals or purposes of the communication or interaction--the agency's and the public's; (d) the kinds of information the public needs and that the agency needs in order to understand the relevant technical and social issues; and (e) the types of communication or involvement that best serve to meet the agency's and the public's goals

  11. In-Fiber Subpicosecond Pulse Shaping for Nonlinear Optical Telecommunication Data Processing at 640 Gbit/s

    Directory of Open Access Journals (Sweden)

    J. Azaña

    2012-01-01

    Full Text Available We review recent work on all-fiber (long-period fiber grating devices for optical pulse shaping, particularly flat-top pulse generation, down to the subpicosecond range and their application for nonlinear switching (demultiplexing of optical time-division multiplexed (OTDM data signals in fiber-optic telecommunication links operating up to 640 Gbit/s. Experiments are presented demonstrating error-free 640-to-10 Gbit/s demultiplexing of the 64 tributary channels using the generated flat-top pulses for temporal gating in a Kerr-effect-based nonlinear optical loop mirror. The use of flat-top pulses has critical benefits in the demultiplexing process, including a significantly increased timing-jitter tolerance (up to ~500 fs, i.e., 30% of the bit period and the associated improvement in the bit-error-rate performance (e.g., with a sensitivity increase of up to ~13 dB as compared with the use of Gaussian-like gating pulses. Long-period fiber grating pulse shapers with reduced polarization dependence are fabricated and successfully used for polarization-independent 640-to-10 Gbit/s demultiplexing experiments.

  12. Nonlinear processing of a multicomponent communication signal by combination-sensitive neurons in the anuran inferior colliculus.

    Science.gov (United States)

    Lee, Norman; Schrode, Katrina M; Bee, Mark A

    2017-09-01

    Diverse animals communicate using multicomponent signals. How a receiver's central nervous system integrates multiple signal components remains largely unknown. We investigated how female green treefrogs (Hyla cinerea) integrate the multiple spectral components present in male advertisement calls. Typical calls have a bimodal spectrum consisting of formant-like low-frequency (~0.9 kHz) and high-frequency (~2.7 kHz) components that are transduced by different sensory organs in the inner ear. In behavioral experiments, only bimodal calls reliably elicited phonotaxis in no-choice tests, and they were selectively chosen over unimodal calls in two-alternative choice tests. Single neurons in the inferior colliculus of awake, passively listening subjects were classified as combination-insensitive units (27.9%) or combination-sensitive units (72.1%) based on patterns of relative responses to the same bimodal and unimodal calls. Combination-insensitive units responded similarly to the bimodal call and one or both unimodal calls. In contrast, combination-sensitive units exhibited both linear responses (i.e., linear summation) and, more commonly, nonlinear responses (e.g., facilitation, compressive summation, or suppression) to the spectral combination in the bimodal call. These results are consistent with the hypothesis that nonlinearities play potentially critical roles in spectral integration and in the neural processing of multicomponent communication signals.

  13. Nonlinear optical and multiphoton processes for in situ manipulation and conversion of photons: applications to energy and healthcare (Conference Presentation)

    Science.gov (United States)

    Prasad, Paras N.

    2017-02-01

    Chiral control of nonlinear optical functions holds a great promise for a wide range of applications including optical signal processing, bio-sensing and chiral bio-imaging. In chiral polyfluorene thin films, we demonstrated extremely large chiral nonlinearity. The physics of manipulating excitation dynamics for photon transformation will be discussed, along with nanochemistry control of upconversion in hierarchically built organic chromophore coupled-core-multiple shell nanostructures which enable introduce new, organic-inorganic energy transfer routes for broadband light harvesting and increased upconversion efficiency via multistep cascaded energy transfer. We are pursuing the applications of photon conversion technology in IR harvesting for photovoltaics, high contrast bioimaging, photoacoustic imaging, photodynamic therapy, and optogenetics. An important application is in Brain research and Neurophotonics for functional mapping and modulation of brain activities. Another new direction pursued is magnetic field control of light in in a chiral polymer nanocomposite to achieve large magneto-optic coefficient which can enable sensing of extremely weak magnetic field due to brain waves. Finally, we will consider the thought provoking concept of utilizing photons to quantify, through magneto-optics, and augment - through nanoptogenetics, the cognitive states, thus paving the path way to a quantified human paradigm.

  14. Localized surface plasmons modulated nonlinear optical processes in metal film-coupled and upconversion nanocrystals-coated nanoparticles (Conference Presentation)

    Science.gov (United States)

    Lei, Dangyuan

    2016-09-01

    In the first part of this talk, I will show our experimental investigation on the linear and nonlinear optical properties of metal film-coupled nanosphere monomers and dimers both with nanometric gaps. We have developed a new methodology - polarization resolved spectral decomposition and color decoding to "visualizing" unambiguously the spectral and radiation properties of the complex plasmonic gap modes in these hybrid nanostructures. Single-particle spectroscopic measurements indicate that these hybrid nanostructures can simultaneously enhance several nonlinear optical processes, such as second harmonic generation, two-photon absorption induced luminescence, and hyper-Raman scattering. In the second part, I will show how the polarization state of the emissions from sub-10 nm upconversion nanocrystals (UCNCs) can be modulated when they form a hybrid complex with a gold nanorod (GNR). Our single-particle scattering experiments expose how an interplay between excitation polarization and GNR orientation gives rise to an extraordinary polarized nature of the upconversion emissions from an individual hybrid nanostructure. We support our results by numerical simulations and, using Förster resonance energy transfer theory, we uncover how an overlap between the UCNC emission and GNR extinction bands as well as the mutual orientation between emission and plasmonic dipoles jointly determine the polarization state of the UC emissions.

  15. Involvement of microRNAs in physiological and pathological processes in the lung

    Directory of Open Access Journals (Sweden)

    Kriegova Eva

    2010-11-01

    Full Text Available Abstract To date, at least 900 different microRNA (miRNA genes have been discovered in the human genome. These short, single-stranded RNA molecules originate from larger precursor molecules that fold to produce hairpin structures, which are subsequently processed by ribonucleases Drosha/Pasha and Dicer to form mature miRNAs. MiRNAs play role in the posttranscriptional regulation of about one third of human genes, mainly via degradation of target mRNAs. Whereas the target mRNAs are often involved in the regulation of diverse physiological processes ranging from developmental timing to apoptosis, miRNAs have a strong potential to regulate fundamental biological processes also in the lung compartment. However, the knowledge of the role of miRNAs in physiological and pathological conditions in the lung is still limited. This review, therefore, summarizes current knowledge of the mechanism, function of miRNAs and their contribution to lung development and homeostasis. Besides the involvement of miRNAs in pulmonary physiological conditions, there is evidence that abnormal miRNA expression may lead to pathological processes and development of various pulmonary diseases. Next, the review describes current state-of-art on the miRNA expression profiles in smoking-related diseases including lung cancerogenesis, in immune system mediated pulmonary diseases and fibrotic processes in the lung. From the current research it is evident that miRNAs may play role in the posttranscriptional regulation of key genes in human pulmonary diseases. Further studies are, therefore, necessary to explore miRNA expression profiles and their association with target mRNAs in human pulmonary diseases.

  16. Adolescent fathers: knowledge of and involvement in the breast feeding process in Brazil.

    Science.gov (United States)

    Torres de Lacerda, Ana Catarina; Lucena de Vasconcelos, Maria Gorete; Nascimento de Alencar, Eloine; Osório, Mônica Maria; Pontes, Cleide Maria

    2014-03-01

    to understand the ways in which adolescent fathers participate in the breast feeding process in the family environment in North-eastern Brazil. a descriptive, exploratory, qualitative study was undertaken involving 10 couples with infants aged 6-8 months living in a single community in Recife, Pernambuco, Brazil. Data were collected using semi-structured interviews with questions to guide the interviewer. Data were analysed using thematic content analysis, and interpreted under the theoretical reference of being an adolescent father within the context of breast feeding. from the data collected, three themes were identified: knowledge of the benefits of breast feeding for the child's health; discontinued participation of the father in breast feeding during the pregnancy-childbearing cycle; and exclusion of the adolescent father from the breast feeding process. The adolescent fathers knew about the benefits of breast feeding in terms of the child's health, but did not mention benefits for the mother, the family or society. For some adolescent fathers, their participation in the breast feeding process started during pregnancy, whereas for others, it was only initiated after the infant was born. One of the fathers was prevented, by his wife and mother-in-law, from participating in the breast feeding process. the involvement of adolescent fathers in the breast feeding process oscillated during the pregnancy-childbearing cycle. This may be due to the patriarchal cultural heritage, Brazilian paternity laws, and the fact that these fathers were adolescents. This study showed that adolescent parents were knowledgeable about breast feeding. Finally, fathers want a new model of parenting in which the man participates in child care. Crown Copyright © 2013. Published by Elsevier Ltd. All rights reserved.

  17. Genes involved in complex adaptive processes tend to have highly conserved upstream regions in mammalian genomes

    Directory of Open Access Journals (Sweden)

    Kohane Isaac

    2005-11-01

    Full Text Available Abstract Background Recent advances in genome sequencing suggest a remarkable conservation in gene content of mammalian organisms. The similarity in gene repertoire present in different organisms has increased interest in studying regulatory mechanisms of gene expression aimed at elucidating the differences in phenotypes. In particular, a proximal promoter region contains a large number of regulatory elements that control the expression of its downstream gene. Although many studies have focused on identification of these elements, a broader picture on the complexity of transcriptional regulation of different biological processes has not been addressed in mammals. The regulatory complexity may strongly correlate with gene function, as different evolutionary forces must act on the regulatory systems under different biological conditions. We investigate this hypothesis by comparing the conservation of promoters upstream of genes classified in different functional categories. Results By conducting a rank correlation analysis between functional annotation and upstream sequence alignment scores obtained by human-mouse and human-dog comparison, we found a significantly greater conservation of the upstream sequence of genes involved in development, cell communication, neural functions and signaling processes than those involved in more basic processes shared with unicellular organisms such as metabolism and ribosomal function. This observation persists after controlling for G+C content. Considering conservation as a functional signature, we hypothesize a higher density of cis-regulatory elements upstream of genes participating in complex and adaptive processes. Conclusion We identified a class of functions that are associated with either high or low promoter conservation in mammals. We detected a significant tendency that points to complex and adaptive processes were associated with higher promoter conservation, despite the fact that they have emerged

  18. Emotion and attention interactions in social cognition: brain regions involved in processing anger prosody.

    Science.gov (United States)

    Sander, David; Grandjean, Didier; Pourtois, Gilles; Schwartz, Sophie; Seghier, Mohamed L; Scherer, Klaus R; Vuilleumier, Patrik

    2005-12-01

    Multiple levels of processing are thought to be involved in the appraisal of emotionally relevant events, with some processes being engaged relatively independently of attention, whereas other processes may depend on attention and current task goals or context. We conducted an event-related fMRI experiment to examine how processing angry voice prosody, an affectively and socially salient signal, is modulated by voluntary attention. To manipulate attention orthogonally to emotional prosody, we used a dichotic listening paradigm in which meaningless utterances, pronounced with either angry or neutral prosody, were presented simultaneously to both ears on each trial. In two successive blocks, participants selectively attended to either the left or right ear and performed a gender-decision on the voice heard on the target side. Our results revealed a functional dissociation between different brain areas. Whereas the right amygdala and bilateral superior temporal sulcus responded to anger prosody irrespective of whether it was heard from a to-be-attended or to-be-ignored voice, the orbitofrontal cortex and the cuneus in medial occipital cortex showed greater activation to the same emotional stimuli when the angry voice was to-be-attended rather than to-be-ignored. Furthermore, regression analyses revealed a strong correlation between orbitofrontal regions and sensitivity on a behavioral inhibition scale measuring proneness to anxiety reactions. Our results underscore the importance of emotion and attention interactions in social cognition by demonstrating that multiple levels of processing are involved in the appraisal of emotionally relevant cues in voices, and by showing a modulation of some emotional responses by both the current task-demands and individual differences.

  19. Cellular processes involved in human epidermal cells exposed to extremely low frequency electric fields.

    Science.gov (United States)

    Collard, J-F; Hinsenkamp, M

    2015-05-01

    We observed on different tissues and organisms a biological response after exposure to pulsed low frequency and low amplitude electric or electromagnetic fields but the precise mechanism of cell response remains unknown. The aim of this publication is to understand, using bioinformatics, the biological relevance of processes involved in the modification of gene expression. The list of genes analyzed was obtained after microarray protocol realized on cultures of human epidermal explants growing on deepidermized human skin exposed to a pulsed low frequency electric field. The directed acyclic graph on a WebGestalt Gene Ontology module shows six categories under the biological process root: "biological regulation", "cellular process", "cell proliferation", "death", "metabolic process" and "response to stimulus". Enriched derived categories are coherent with the type of in vitro culture, the stimulation protocol or with the previous results showing a decrease of cell proliferation and an increase of differentiation. The Kegg module on WebGestalt has highlighted "cell cycle" and "p53 signaling pathway" as significantly involved. The Kegg website brings out interactions between FoxO, MAPK, JNK, p53, p38, PI3K/Akt, Wnt, mTor or NF-KappaB. Some genes expressed by the stimulation are known to have an exclusive function on these pathways. Analyses performed with Pathway Studio linked cell proliferation, cell differentiation, apoptosis, cell cycle, mitosis, cell death etc. with our microarrays results. Medline citation generated by the software and the fold change variation confirms a diminution of the proliferation, activation of the differentiation and a less well-defined role of apoptosis or wound healing. Wnt and DKK functional classes, DKK1, MACF1, ATF3, MME, TXNRD1, and BMP-2 genes proposed in previous publications after a manual analysis are also highlighted with other genes after Pathway Studio automatic procedure. Finally, an analysis conducted on a list of genes

  20. Reflective processes and competencies involved in teaching practice at university: a case study

    Directory of Open Access Journals (Sweden)

    Caetano da Costa

    2010-01-01

    Full Text Available Founded on practical rationality, this qualitative case study aimed to explore the teaching practice at university, focusing on teacher's reflections and competencies. To this end, teaching practices were described, analyzed, and interpreted. These interactions with students on a course in the pharmacy program, brought about situations involving dilemmas and learning opportunities for problem-solving and decision-making skills. Throughout the study, students were encouraged to use knowledge-in-action, reflection-in-action, and reflection-on-action, and these processes were also experienced by the teacher. Analysis of the records from classroom observation and the interviews with students and the teacher showed the fundamental role of such reflective processes, which led to attainment of the intended objectives. In this sense, the teacher's reflective practice was essential for supporting the application of each curricular component of the course.

  1. A Traveller Information System: Minimisation of the Number of Graphs’ Nodes Involved When Processing Route Requests

    Directory of Open Access Journals (Sweden)

    Bendaoud Zakaria

    2014-12-01

    Full Text Available The number of people using public transport is continuously increasing. Transport companies want to fulfil travellers’ expectations wherever possible. However, the great number of public transport companies operating in the same area can sometimes confuse travellers as to which route they should take and how to obtain the information relative to their journey. In this paper we suggest integrating several traveller information systems from different companies into the same multimodal information system, offering companies the choice not to share their data. This encourages them to join the system. Additionally, we have minimised the number of nodes involved when processing travellers’ requests in order to simplify the calculation process. To put our plan into action, we have opted for a multi-agent system coupled with the Voronoi decomposition for managing the network.

  2. Nonlinear Krylov acceleration of reacting flow codes

    Energy Technology Data Exchange (ETDEWEB)

    Kumar, S.; Rawat, R.; Smith, P.; Pernice, M. [Univ. of Utah, Salt Lake City, UT (United States)

    1996-12-31

    We are working on computational simulations of three-dimensional reactive flows in applications encompassing a broad range of chemical engineering problems. Examples of such processes are coal (pulverized and fluidized bed) and gas combustion, petroleum processing (cracking), and metallurgical operations such as smelting. These simulations involve an interplay of various physical and chemical factors such as fluid dynamics with turbulence, convective and radiative heat transfer, multiphase effects such as fluid-particle and particle-particle interactions, and chemical reaction. The governing equations resulting from modeling these processes are highly nonlinear and strongly coupled, thereby rendering their solution by traditional iterative methods (such as nonlinear line Gauss-Seidel methods) very difficult and sometimes impossible. Hence we are exploring the use of nonlinear Krylov techniques (such as CMRES and Bi-CGSTAB) to accelerate and stabilize the existing solver. This strategy allows us to take advantage of the problem-definition capabilities of the existing solver. The overall approach amounts to using the SIMPLE (Semi-Implicit Method for Pressure-Linked Equations) method and its variants as nonlinear preconditioners for the nonlinear Krylov method. We have also adapted a backtracking approach for inexact Newton methods to damp the Newton step in the nonlinear Krylov method. This will be a report on work in progress. Preliminary results with nonlinear GMRES have been very encouraging: in many cases the number of line Gauss-Seidel sweeps has been reduced by about a factor of 5, and increased robustness of the underlying solver has also been observed.

  3. Qualified public involvement in the decision making process of siting a waste repository

    International Nuclear Information System (INIS)

    Rodrigues, Danielle Monegalha; Almeida, Ivan Pedro Salati de

    2009-01-01

    The main objective of this paper is to identify the most important characteristics required for the qualification of local communities for participating in the process of defining a specific site for a radioactive waste repository. It also compares the strategies used by Hungary, United Kingdom and Belgium to stimulate the public participation in the decision-making process of building and operating a radioactive waste repository, considering both the stepwise process and the spontaneous candidacy. Two main aspects are discussed as prerequisites to constitute a qualified public. The first aspect is how well the person or entity can be considered an effective representative of the community affected by the repository. This means the conditions the representative has to speak on behalf of the community and participate in the decision making process as its voice. The second characteristic is the level and quality of the information that the community and its representatives must have to participate actively in the decision-making process and what can be done to improve this status. Referring to the strategy to public involvement, this paper discusses the importance of transparency in the process, aiming the credibility of the entrepreneur as the first pace to gaining the confidence of the public affected by the project. Implementing an open dialog and listening to the needs and claims of the population are the first steps to being accepted as a true partner of the community. Preliminary discussions and explanations are important to introduce the subject and to reduce beliefs of false threats in the affected community. The constitution of a local committee is suggested, to act as a legal and formal channel to facilitate the partnership between local community, neighbors and the entrepreneur in order to achieve a positive result in the whole process. (author)

  4. Nonlinear Structuring and High-energy Electrons: Role in Ionosphere and in Thunderstorm Atmosphere Processes

    Science.gov (United States)

    2010-05-01

    Processes Aleksander Viktorovich Gurevich P. N. Lebedev Physical Institute Leninsky pr.,53 Moscow, Russia 117924 EOARD ISTC 06...Electrons: Role in Ionosphere and in Thunderstorm Atmosphere Processes 5a. CONTRACT NUMBER ISTC Registration No: 3641p 5b. GRANT NUMBER... ISTC

  5. Optimization of nonlinear, non-Gaussian Bayesian filtering for diagnosis and prognosis of monotonic degradation processes

    Science.gov (United States)

    Corbetta, Matteo; Sbarufatti, Claudio; Giglio, Marco; Todd, Michael D.

    2018-05-01

    The present work critically analyzes the probabilistic definition of dynamic state-space models subject to Bayesian filters used for monitoring and predicting monotonic degradation processes. The study focuses on the selection of the random process, often called process noise, which is a key perturbation source in the evolution equation of particle filtering. Despite the large number of applications of particle filtering predicting structural degradation, the adequacy of the picked process noise has not been investigated. This paper reviews existing process noise models that are typically embedded in particle filters dedicated to monitoring and predicting structural damage caused by fatigue, which is monotonic in nature. The analysis emphasizes that existing formulations of the process noise can jeopardize the performance of the filter in terms of state estimation and remaining life prediction (i.e., damage prognosis). This paper subsequently proposes an optimal and unbiased process noise model and a list of requirements that the stochastic model must satisfy to guarantee high prognostic performance. These requirements are useful for future and further implementations of particle filtering for monotonic system dynamics. The validity of the new process noise formulation is assessed against experimental fatigue crack growth data from a full-scale aeronautical structure using dedicated performance metrics.

  6. Decision process involved in preparing the Shippingport reactor pressure vessel for transport

    International Nuclear Information System (INIS)

    Murphie, W.E.

    1989-01-01

    The most significant part of the Shippingport Station Decommissioning Project was the one-piece removal and shipment of the reactor pressure vessel (RPV). Implicit in the RPV transport was the task of qualifying the RPV as a waste package acceptable for shipment. Soon after physical decommissioning began on September 1985, questions regarding the packaging certification and transport of the RPV from Shippingport, Pennsylvania to the US Department of Energy (DOE) Hanford Waste Burial Site necessitated reexamination of several planning assumptions. A complete reassessment of the regulatory requirements governing the RPV shipment resulted in a programmatic decision to obtain a type B(U) Certificate of Compliance and abandon the originally planned US Department of Transportation (DOT) low specific activity (LSA) shipment. The decision process resulting in this conclusion was extensive and involved many organizations and agencies. Incidental to this process, several subtle certification issues were identified that required resolution. Some of these issues involved the definition of LSA material for large packages; interpretation and compliance with DOE, DOT and US Nuclear Regulatory Commission (NRC) regulations for the transport of radioactive material; incorporation of the International Atomic Energy Agency (IAEA) regulations by the Panama Canal; and DOE policy requiring advance notification to states of radioactive waste shipments. 2 figs

  7. Aspects of Information Architecture involved in process mapping in Military Organizations under the semiotic perspective

    Directory of Open Access Journals (Sweden)

    Mac Amaral Cartaxo

    2016-04-01

    Full Text Available Introduction: The description of the processes to represent the activities in an organization has important call semiotic, It is the flowcharts of uses, management reports and the various forms of representation of the strategies used. The subsequent interpretation of the organization's employees involved in learning tasks and the symbols used to translate the meanings of management practices is essential role for the organization. Objective: The objective of this study was to identify evidence of conceptual and empirical, on aspects of information architecture involved in the mapping process carried out in military organizations under the semiotic perspective. Methodology: The research is characterized as qualitative, case study and the data collection technique was the semi-structured interview, applied to management advisors. Results: The main results indicate that management practices described with the use of pictorial symbols and different layouts have greater impact to explain the relevance of management practices and indicators. Conclusion: With regard to the semiotic appeal, it was found that the impact of a management report is significant due to the use of signs and layout that stimulate further reading by simplifying complex concepts in tables, diagrams summarizing lengthy descriptions.

  8. Decision process involved in preparing the Shippingport reactor pressure vessel for transport

    International Nuclear Information System (INIS)

    Murphie, W.E.

    1990-01-01

    The most significant part of the Shippingport Station Decommissioning Project was the one-piece removal and shipment of the reactor pressure vessel (RPV). Implicit in the RPV transport was the task of qualifying the RPV as a waste package acceptable for shipment. Soon after physical decommissioning began on September, 1985, questions regarding the packaging certification and transport of the RPV from Shippingport, Pennsylvania to the U.S. Department of Energy (DOE) Hanford waste burial site necessitated reexamination of several planning assumptions. A complete reassessment of the regulatory requirements governing the RPV shipment resulting in a programmatic decision to obtain a Type B(U) Certification of Compliance and abandon the originally planned U.S. Department of Transportation (DOT) low specific activity (LSA) shipment. The decision process resulting in this conclusion was extensive and involved many organizations and agencies. Incidental to this process, several subtle certification issues were identified that required resolution. Some of these issues involved the definition of LSA material for large packages; interpretation and compliance with DOE, DOT and U.S. Nuclear Regulatory Commission (NRC) regulations for the transport of radioactive material; incorporation of the International Atomic Energy Agency (IAEA) regulations by the Panama Canal; and DOE policy requiring advance notification to states of radioactive waste shipments

  9. Modeling of long-range memory processes with inverse cubic distributions by the nonlinear stochastic differential equations

    Science.gov (United States)

    Kaulakys, B.; Alaburda, M.; Ruseckas, J.

    2016-05-01

    A well-known fact in the financial markets is the so-called ‘inverse cubic law’ of the cumulative distributions of the long-range memory fluctuations of market indicators such as a number of events of trades, trading volume and the logarithmic price change. We propose the nonlinear stochastic differential equation (SDE) giving both the power-law behavior of the power spectral density and the long-range dependent inverse cubic law of the cumulative distribution. This is achieved using the suggestion that when the market evolves from calm to violent behavior there is a decrease of the delay time of multiplicative feedback of the system in comparison to the driving noise correlation time. This results in a transition from the Itô to the Stratonovich sense of the SDE and yields a long-range memory process.

  10. Numerical simulations of industrial processes involving fluid dynamics, combustion and radiation

    Energy Technology Data Exchange (ETDEWEB)

    Ducrocq, J [Air Liquide, Centre de Recherche Claude-Delorme, Jouy-en-Josas (France)

    1998-12-31

    Moving out of the scientific community research laboratories, computational fluid dynamics (CFD) software packages are now allowing industrials to analyse and optimize industrial processes involving the use of gases, liquids and even some two-phase fluids. Their attractiveness and their impact stems out from the opportunity they offer to bring insight into an existing unit, or even at the design stage, by displaying the spatial distribution of process relevant variables such as temperature, concentration. The filling of the spacing in between a two-layer window is a simple example. This new opportunity of visualisation is at times an unique way, when the process environment is an opaque one, such as liquid metal flowing into a tundish or when measurements of flows may be a long and tedious work, such as flows within water treatment basins. This environment we are to investigate in order to optimize can also be a harsh one, due to its high temperature level for example. Such are burners. But then pure fluid flow analysis, such as cold flow water models, has too many shortcomings. The description of combustion processes and of radiation become a necessary feature in order to describe thermal heat transfer or to locate `hot spots`. Such numerical models showing our oxycombustion expertise in glass melting will be presented. (author)

  11. Hemispheric involvement in the processing of Chinese idioms: An fMRI study.

    Science.gov (United States)

    Yang, Jie; Li, Ping; Fang, Xiaoping; Shu, Hua; Liu, Youyi; Chen, Lang

    2016-07-01

    Although the left hemisphere is believed to handle major language functions, the role of the right hemisphere in language comprehension remains controversial. Recently researchers have investigated hemispheric language processing with figurative language materials (e.g., metaphors, jokes, and idioms). The current study capitalizes on the pervasiveness and distinct features of Chinese idioms to examine the brain mechanism of figurative language processing. Native Chinese speakers performed a non-semantic task while reading opaque idioms, transparent idioms, and non-idiomatic literal phrases. Whole-brain analyses indicated strong activations for all three conditions in an overlapping brain network that includes the bilateral inferior/middle frontal gyrus and the temporo-parietal and occipital-temporal regions. The two idiom conditions elicited additional activations in the right superior parietal lobule and right precuneus. Item-based modulation analyses further demonstrated that activation amplitudes in the right angular gyrus, right superior parietal lobule and right precuneus, as well as left inferior temporo-occipital cortex, are negatively correlated with the semantic transparency of the idioms. These results suggest that both hemispheres are involved in idiom processing but they play different roles. Implications of the findings are discussed in light of theories of figurative language processing and hemispheric functions. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. Diurnal rhythmicity in biological processes involved in bioavailability of functional food factors.

    Science.gov (United States)

    Tsurusaki, Takashi; Sakakibara, Hiroyuki; Aoshima, Yoshiki; Yamazaki, Shunsuke; Sakono, Masanobu; Shimoi, Kayoko

    2013-05-01

    In the past few decades, many types of functional factors have been identified in dietary foods; for example, flavonoids are major groups widely distributed in the plant kingdom. However, the absorption rates of the functional food factors are usually low, and many of these are difficult to be absorbed in the intact forms because of metabolization by biological processes during absorption. To gain adequate beneficial effects, it is therefore mandatory to know whether functional food factors are absorbed in sufficient quantity, and then reach target organs while maintaining beneficial effects. These are the reasons why the bioavailability of functional food factors has been well investigated using rodent models. Recently, many of the biological processes have been reported to follow diurnal rhythms recurring every 24 h. Therefore, absorption and metabolism of functional food factors influenced by the biological processes may vary with time of day. Consequently, the evaluation of the bioavailability of functional food factors using rodent models should take into consideration the timing of consumption. In this review, we provide a perspective overview of the diurnal rhythm of biological processes involved in the bioavailability of functional food factors, particularly flavonoids.

  13. Numerical simulations of industrial processes involving fluid dynamics, combustion and radiation

    Energy Technology Data Exchange (ETDEWEB)

    Ducrocq, J. [Air Liquide, Centre de Recherche Claude-Delorme, Jouy-en-Josas (France)

    1997-12-31

    Moving out of the scientific community research laboratories, computational fluid dynamics (CFD) software packages are now allowing industrials to analyse and optimize industrial processes involving the use of gases, liquids and even some two-phase fluids. Their attractiveness and their impact stems out from the opportunity they offer to bring insight into an existing unit, or even at the design stage, by displaying the spatial distribution of process relevant variables such as temperature, concentration. The filling of the spacing in between a two-layer window is a simple example. This new opportunity of visualisation is at times an unique way, when the process environment is an opaque one, such as liquid metal flowing into a tundish or when measurements of flows may be a long and tedious work, such as flows within water treatment basins. This environment we are to investigate in order to optimize can also be a harsh one, due to its high temperature level for example. Such are burners. But then pure fluid flow analysis, such as cold flow water models, has too many shortcomings. The description of combustion processes and of radiation become a necessary feature in order to describe thermal heat transfer or to locate `hot spots`. Such numerical models showing our oxycombustion expertise in glass melting will be presented. (author)

  14. Nonlinear fluctuation-induced rate equations for linear birth-death processes

    International Nuclear Information System (INIS)

    Honkonen, J.

    2008-01-01

    The Fock-space approach to the solution of master equations for the one-step Markov processes is reconsidered. It is shown that in birth-death processes with an absorbing state at the bottom of the occupation-number spectrum and occupation-number independent annihilation probability occupation-number fluctuations give rise to rate equations drastically different from the polynomial form typical of birth-death processes. The fluctuation-induced rate equations with the characteristic exponential terms are derived for Mikhailov's ecological model and Lanchester's model of modern warfare

  15. Nonlinear fluctuations-induced rate equations for linear birth-death processes

    Science.gov (United States)

    Honkonen, J.

    2008-05-01

    The Fock-space approach to the solution of master equations for one-step Markov processes is reconsidered. It is shown that in birth-death processes with an absorbing state at the bottom of the occupation-number spectrum and occupation-number independent annihilation probability of occupation-number fluctuations give rise to rate equations drastically different from the polynomial form typical of birth-death processes. The fluctuation-induced rate equations with the characteristic exponential terms are derived for Mikhailov’s ecological model and Lanchester’s model of modern warfare.

  16. Generalized Nonlinear Yule Models

    OpenAIRE

    Lansky, Petr; Polito, Federico; Sacerdote, Laura

    2016-01-01

    With the aim of considering models with persistent memory we propose a fractional nonlinear modification of the classical Yule model often studied in the context of macrovolution. Here the model is analyzed and interpreted in the framework of the development of networks such as the World Wide Web. Nonlinearity is introduced by replacing the linear birth process governing the growth of the in-links of each specific webpage with a fractional nonlinear birth process with completely general birth...

  17. Processes and parameters involved in modeling radionuclide transport from bedded salt repositories. Final report. Technical memorandum

    International Nuclear Information System (INIS)

    Evenson, D.E.; Prickett, T.A.; Showalter, P.A.

    1979-07-01

    The parameters necessary to model radionuclide transport in salt beds are identified and described. A proposed plan for disposal of the radioactive wastes generated by nuclear power plants is to store waste canisters in repository sites contained in stable salt formations approximately 600 meters below the ground surface. Among the principal radioactive wastes contained in these canisters will be radioactive isotopes of neptunium, americium, uranium, and plutonium along with many highly radioactive fission products. A concern with this form of waste disposal is the possibility of ground-water flow occurring in the salt beds and endangering water supplies and the public health. Specifically, the research investigated the processes involved in the movement of radioactive wastes from the repository site by groundwater flow. Since the radioactive waste canisters also generate heat, temperature is an important factor. Among the processes affecting movement of radioactive wastes from a repository site in a salt bed are thermal conduction, groundwater movement, ion exchange, radioactive decay, dissolution and precipitation of salt, dispersion and diffusion, adsorption, and thermomigration. In addition, structural changes in the salt beds as a result of temperature changes are important. Based upon the half-lives of the radioactive wastes, he period of concern is on the order of a million years. As a result, major geologic phenomena that could affect both the salt bed and groundwater flow in the salt beds was considered. These phenomena include items such as volcanism, faulting, erosion, glaciation, and the impact of meteorites. CDM reviewed all of the critical processes involved in regional groundwater movement of radioactive wastes and identified and described the parameters that must be included to mathematically model their behavior. In addition, CDM briefly reviewed available echniques to measure these parameters

  18. Public Involvement in Repository Site Selection for Nuclear Waste: Towards a more Dynamic View in Decision-Making Processes

    Energy Technology Data Exchange (ETDEWEB)

    Kruetli, Pius; Stauffacher, Michael; Flueeler, Thomas; Scholz, Roland W. [ETH Zuerich (Switzerland). lnst. for Human-Environment Systems (HES)

    2006-09-15

    This paper discusses possibilities of public involvement in radioactive waste management. A general overview of the radioactive waste issue is presented referring to a proposed model of the respective decision-making process. Based on the well known participation ladder by Arnstein, we differentiate various intensities of public involvement. A matrix with public involvement and the decision-making process is introduced and three prototypical patterns are discussed. We conclude that time frame, the level of public involvement and the mission have to be considered as well as techniques and the overarching context - all in all, a systematic and dynamic approach for public involvement is needed.

  19. Public Involvement in Repository Site Selection for Nuclear Waste: Towards a more Dynamic View in Decision-Making Processes

    International Nuclear Information System (INIS)

    Kruetli, Pius; Stauffacher, Michael; Flueeler, Thomas; Scholz, Roland W.

    2006-01-01

    This paper discusses possibilities of public involvement in radioactive waste management. A general overview of the radioactive waste issue is presented referring to a proposed model of the respective decision-making process. Based on the well known participation ladder by Arnstein, we differentiate various intensities of public involvement. A matrix with public involvement and the decision-making process is introduced and three prototypical patterns are discussed. We conclude that time frame, the level of public involvement and the mission have to be considered as well as techniques and the overarching context - all in all, a systematic and dynamic approach for public involvement is needed

  20. Study of the mechanisms involved in the laser superficial hardening process of metallic alloys

    International Nuclear Information System (INIS)

    Silva, Edmara Marques Rodrigues da

    2001-01-01

    The laser superficial hardening process of a ferrous alloy (gray cast iron) and of an aluminum-silicon alloy was investigated in this work. These metallic alloys are used in the automobile industry for manufacturing cylinders and pistons, respectively. By application of individual pulses and single tracks, the involved mechanisms during the processing were studied. Variables such as energy density, power density, temporal width, beam diameter on the sample surface, atmosphere of the processing region, overlapping and scanning velocity. The hardened surface was characterized by optical and scanning electronic microscopy, dispersive energy microanalysis, X-ray mapping, X-ray diffraction, and measurements of roughness and Vickers microhardness. Depending on the processing parameters, it is possible to obtain different microstructures. The affected area of gray cast iron, can be hardened by remelting or transformation hardening (total or partial) if the reached temperature is higher or not that of melting temperature. Laser treatment originated new structures such as retained austenite, martensite and, occasionally, eutectic of cellular dendritic structure. Aluminum-silicon alloy does not have phase transformation in solid state, it can be hardened only by remelting. The increase of hardness is a function of the precipitation hardening process, which makes the silicon particles smaller and more disperse in the matrix. Maximal values of microhardness (700-1000 HV) were reached with the laser treatment in gray cast iron samples. The initial microhardness is of 242 HV. For aluminum-silicon alloy, the laser remelting increases the initial microhardness of 128 HV to the range of 160-320 HV. The found results give a new perspective for using the CLA/IPEN's laser in the heat treatment area. Besides providing a higher absorptivity to the materials, compared with the CO 2 laser, and optical fiber access, the superficial hardening with Nd:YAG laser, depending on the level of

  1. Optimal nonlinear information processing capacity in delay-based reservoir computers

    Science.gov (United States)

    Grigoryeva, Lyudmila; Henriques, Julie; Larger, Laurent; Ortega, Juan-Pablo

    2015-09-01

    Reservoir computing is a recently introduced brain-inspired machine learning paradigm capable of excellent performances in the processing of empirical data. We focus in a particular kind of time-delay based reservoir computers that have been physically implemented using optical and electronic systems and have shown unprecedented data processing rates. Reservoir computing is well-known for the ease of the associated training scheme but also for the problematic sensitivity of its performance to architecture parameters. This article addresses the reservoir design problem, which remains the biggest challenge in the applicability of this information processing scheme. More specifically, we use the information available regarding the optimal reservoir working regimes to construct a functional link between the reservoir parameters and its performance. This function is used to explore various properties of the device and to choose the optimal reservoir architecture, thus replacing the tedious and time consuming parameter scannings used so far in the literature.

  2. Harvesting thermal fluctuations: Activation process induced by a nonlinear chain in thermal equilibrium

    International Nuclear Information System (INIS)

    Reigada, Ramon; Sarmiento, Antonio; Romero, Aldo H.; Sancho, J. M.; Lindenberg, Katja

    2000-01-01

    We present a model in which the immediate environment of a bistable system is a molecular chain which in turn is connected to a thermal environment of the Langevin form. The molecular chain consists of masses connected by harmonic or by anharmonic springs. The distribution, intensity, and mobility of thermal fluctuations in these chains is strongly dependent on the nature of the springs and leads to different transition dynamics for the activated process. Thus, all else (temperature, damping, coupling parameters between the chain and the bistable system) being the same, the hard chain may provide an environment described as diffusion-limited and more effective in the activation process, while the soft chain may provide an environment described as energy-limited and less effective. The importance of a detailed understanding of the thermal environment toward the understanding of the activation process itself is thus highlighted. (c) 2000 American Institute of Physics

  3. Signal Processing using Nonlinear Optical Eects in Single- and Few-Mode Fibers

    DEFF Research Database (Denmark)

    Friis, Søren Michael Mørk

    noise, loss, and pump depletion on the noise properties of parametric frequency conversion and phase-insensitive and phase-sensitive parametric amplification. An important part of realizing space-division multiplexing is the ability of optical signal processing so the second part of this thesis......-wave mixing in two-mode fibers acvi counting for six simultaneous processes is derived, and the conversion efficiency from signal to idler in the four-wave mixing processes of phase conjugation and Bragg scattering in two two-mode fibers with different phase matching properties are experimentally investigated......The stagnating increase in data transmission capacity in optical communication systems combined with the ever growing demand of transmission bandwidth is leading to an impending capacity crunch, referring to the point in time after which the available bandwidth of the individual user starts...

  4. Processing concrete words: fMRI evidence against a specific right-hemisphere involvement.

    Science.gov (United States)

    Fiebach, Christian J; Friederici, Angela D

    2004-01-01

    Behavioral, patient, and electrophysiological studies have been taken as support for the assumption that processing of abstract words is confined to the left hemisphere, whereas concrete words are processed also by right-hemispheric brain areas. These are thought to provide additional information from an imaginal representational system, as postulated in the dual-coding theory of memory and cognition. Here we report new event-related fMRI data on the processing of concrete and abstract words in a lexical decision task. While abstract words activated a subregion of the left inferior frontal gyrus (BA 45) more strongly than concrete words, specific activity for concrete words was observed in the left basal temporal cortex. These data as well as data from other neuroimaging studies reviewed here are not compatible with the assumption of a specific right-hemispheric involvement for concrete words. The combined findings rather suggest a revised view of the neuroanatomical bases of the imaginal representational system assumed in the dual-coding theory, at least with respect to word recognition.

  5. Social anxiety disorder exhibit impaired networks involved in self and theory of mind processing.

    Science.gov (United States)

    Cui, Qian; Vanman, Eric J; Long, Zhiliang; Pang, Yajing; Chen, Yuyan; Wang, Yifeng; Duan, Xujun; Chen, Heng; Gong, Qiyong; Zhang, Wei; Chen, Huafu

    2017-08-01

    Most previous studies regarding social anxiety disorder (SAD) have focused on the role of emotional dysfunction, while impairments in self- and theory of mind (ToM)-processing have relatively been neglected. This study utilised functional connectivity density (FCD), resting-state functional connectivity (RSFC) and discriminant analyses to investigate impairments in self- and ToM-related networks in patients with SAD. Patients with SAD exhibited decreased long-range FCD in the right rostral anterior cingulate cortex (rACC) and decreased short-range FCD in the right superior temporal gyrus (STG)-key nodes involved in self- and ToM-processing, respectively. Decreased RSFC of the right rACC and STG with widespread frontal, temporal, posteromedial, sensorimotor, and somatosensory, regions was also observed in patients with SAD. Altered RSFC between the right rACC and bilateral superior frontal gyrus, between the right rACC and right middle frontal gyrus, and within the right STG itself provided the greatest contribution to individual diagnoses of SAD, with an accuracy of 84.5%. These results suggest that a lack of cognitive inhibition on emotional self-referential processing as well as impairments in social information integration may play critical roles in the pathomechanism of SAD and highlight the importance of recognising such features in the diagnosis and treatment of SAD. © The Author (2017). Published by Oxford University Press.

  6. Social Impact of Participatory Health Research: Collaborative Non-Linear Processes of Knowledge Mobilization

    Science.gov (United States)

    Abma, Tineke A.; Cook, Tina; Rämgård, Margaretha; Kleba, Elisabeth; Harris, Janet; Wallerstein, Nina

    2017-01-01

    Social impact, defined as an effect on society, culture, quality of life, community services, or public policy beyond academia, is widely considered as a relevant requirement for scientific research, especially in the field of health care. Traditionally, in health research, the process of knowledge transfer is rather linear and one-sided and has…

  7. Nonlinear Parasitic Capacitance Modelling of High Voltage Power MOSFETs in Partial SOI Process

    DEFF Research Database (Denmark)

    Fan, Lin; Knott, Arnold; Jørgensen, Ivan Harald Holger

    2016-01-01

    : off-state, sub-threshold region, and on-state in the linear region. A high voltage power MOSFET is designed in a partial Silicon on Insulator (SOI) process, with the bulk as a separate terminal. 3D plots and contour plots of the capacitances versus bias voltages for the transistor summarize...

  8. Streptomyces lunalinharesii Strain 235 Shows the Potential to Inhibit Bacteria Involved in Biocorrosion Processes

    Directory of Open Access Journals (Sweden)

    Juliana Pacheco da Rosa

    2013-01-01

    Full Text Available Four actinomycete strains previously isolated from Brazilian soils were tested for their antimicrobial activity against Bacillus pumilus LF-4 and Desulfovibrio alaskensis NCIMB 13491, bacteria that are well known to be involved in biofilm formation and biocorrosion. Strain 235, belonging to the species Streptomyces lunalinharesii, inhibited the growth of both bacteria. The antimicrobial activity was seen over a wide range of pH, and after treatment with several chemicals and heat but not with proteinase K and trypsin. The antimicrobial substances present in the concentrated supernatant from growth media were partially characterized by SDS-PAGE and extracellular polypeptides were seen. Bands in the size range of 12 to 14.4 kDa caused antimicrobial activity. Transmission electron microscopy of D. alaskensis cells treated with the concentrated supernatant containing the antimicrobial substances revealed the formation of prominent bubbles, the spherical double-layered structures on the cell membrane, and the periplasmic space completely filled with electron-dense material. This is the first report on the production of antimicrobial substances by actinomycetes against bacteria involved in biocorrosion processes, and these findings may be of great relevance as an alternative source of biocides to those currently employed in the petroleum industry.

  9. Streptomyces lunalinharesii strain 235 shows the potential to inhibit bacteria involved in biocorrosion processes.

    Science.gov (United States)

    Pacheco da Rosa, Juliana; Korenblum, Elisa; Franco-Cirigliano, Marcella Novaes; Abreu, Fernanda; Lins, Ulysses; Soares, Rosângela M A; Macrae, Andrew; Seldin, Lucy; Coelho, Rosalie R R

    2013-01-01

    Four actinomycete strains previously isolated from Brazilian soils were tested for their antimicrobial activity against Bacillus pumilus LF-4 and Desulfovibrio alaskensis NCIMB 13491, bacteria that are well known to be involved in biofilm formation and biocorrosion. Strain 235, belonging to the species Streptomyces lunalinharesii, inhibited the growth of both bacteria. The antimicrobial activity was seen over a wide range of pH, and after treatment with several chemicals and heat but not with proteinase K and trypsin. The antimicrobial substances present in the concentrated supernatant from growth media were partially characterized by SDS-PAGE and extracellular polypeptides were seen. Bands in the size range of 12 to 14.4 kDa caused antimicrobial activity. Transmission electron microscopy of D. alaskensis cells treated with the concentrated supernatant containing the antimicrobial substances revealed the formation of prominent bubbles, the spherical double-layered structures on the cell membrane, and the periplasmic space completely filled with electron-dense material. This is the first report on the production of antimicrobial substances by actinomycetes against bacteria involved in biocorrosion processes, and these findings may be of great relevance as an alternative source of biocides to those currently employed in the petroleum industry.

  10. Neural responses to ambiguity involve domain-general and domain-specific emotion processing systems.

    Science.gov (United States)

    Neta, Maital; Kelley, William M; Whalen, Paul J

    2013-04-01

    Extant research has examined the process of decision making under uncertainty, specifically in situations of ambiguity. However, much of this work has been conducted in the context of semantic and low-level visual processing. An open question is whether ambiguity in social signals (e.g., emotional facial expressions) is processed similarly or whether a unique set of processors come on-line to resolve ambiguity in a social context. Our work has examined ambiguity using surprised facial expressions, as they have predicted both positive and negative outcomes in the past. Specifically, whereas some people tended to interpret surprise as negatively valenced, others tended toward a more positive interpretation. Here, we examined neural responses to social ambiguity using faces (surprise) and nonface emotional scenes (International Affective Picture System). Moreover, we examined whether these effects are specific to ambiguity resolution (i.e., judgments about the ambiguity) or whether similar effects would be demonstrated for incidental judgments (e.g., nonvalence judgments about ambiguously valenced stimuli). We found that a distinct task control (i.e., cingulo-opercular) network was more active when resolving ambiguity. We also found that activity in the ventral amygdala was greater to faces and scenes that were rated explicitly along the dimension of valence, consistent with findings that the ventral amygdala tracks valence. Taken together, there is a complex neural architecture that supports decision making in the presence of ambiguity: (a) a core set of cortical structures engaged for explicit ambiguity processing across stimulus boundaries and (b) other dedicated circuits for biologically relevant learning situations involving faces.

  11. Linear and nonlinear post-processing of numerically forecasted surface temperature

    Directory of Open Access Journals (Sweden)

    M. Casaioli

    2003-01-01

    Full Text Available In this paper we test different approaches to the statistical post-processing of gridded numerical surface air temperatures (provided by the European Centre for Medium-Range Weather Forecasts onto the temperature measured at surface weather stations located in the Italian region of Puglia. We consider simple post-processing techniques, like correction for altitude, linear regression from different input parameters and Kalman filtering, as well as a neural network training procedure, stabilised (i.e. driven into the absolute minimum of the error function over the learning set by means of a Simulated Annealing method. A comparative analysis of the results shows that the performance with neural networks is the best. It is encouraging for systematic use in meteorological forecast-analysis service operations.

  12. Signal Processing for Neuroscientists, A Companion Volume Advanced Topics, Nonlinear Techniques and Multi-Channel Analysis

    CERN Document Server

    van Drongelen, Wim

    2010-01-01

    The popularity of signal processing in neuroscience is increasing, and with the current availability and development of computer hardware and software, it is anticipated that the current growth will continue. Because electrode fabrication has improved and measurement equipment is getting less expensive, electrophysiological measurements with large numbers of channels are now very common. In addition, neuroscience has entered the age of light, and fluorescence measurements are fully integrated into the researcher's toolkit. Because each image in a movie contains multiple pixels, these measureme

  13. Nonlinear dispersion-based incoherent photonic processing for microwave pulse generation with full reconfigurability.

    Science.gov (United States)

    Bolea, Mario; Mora, José; Ortega, Beatriz; Capmany, José

    2012-03-12

    A novel all-optical technique based on the incoherent processing of optical signals using high-order dispersive elements is analyzed for microwave arbitrary pulse generation. We show an approach which allows a full reconfigurability of a pulse in terms of chirp, envelope and central frequency by the proper control of the second-order dispersion and the incoherent optical source power distribution, achieving large values of time-bandwidth product.

  14. High-order nonlinear optical processes in ablated carbon-containing materials: Recent approaches in development of the nonlinear spectroscopy using harmonic generation in the extreme ultraviolet range

    Science.gov (United States)

    Ganeev, R. A.

    2017-08-01

    The nonlinear spectroscopy using harmonic generation in the extreme ultraviolet range became a versatile tool for the analysis of the optical, structural and morphological properties of matter. The carbon-contained materials have shown the advanced properties among other studied species, which allowed both the definition of the role of structural properties on the nonlinear optical response and the analysis of the fundamental features of carbon as the attractive material for generation of coherent short-wavelength radiation. We review the studies of the high-order harmonic generation by focusing ultrashort pulses into the plasmas produced during laser ablation of various organic compounds. We discuss the role of ionic transitions of ablated carbon-containing molecules on the harmonic yield. We also show the similarities and distinctions of the harmonic and plasma spectra of organic compounds and graphite. We discuss the studies of the generation of harmonics up to the 27th order (λ = 29.9 nm) of 806 nm radiation in the boron carbide plasma and analyze the advantages and disadvantages of this target compared with the ingredients comprising B4C (solid boron and graphite) by comparing plasma emission and harmonic spectra from three species. We also show that the coincidence of harmonic and plasma emission wavelengths in most cases does not cause the enhancement or decrease of the conversion efficiency of this harmonic.

  15. LAMMER kinase Kic1 is involved in pre-mRNA processing

    International Nuclear Information System (INIS)

    Tang, Zhaohua; Luca, Maria; Portillio, Jessica; Ngo, Benson; Chang, Cathey; Wen, Teresa; Murray, Johanne; Carr, Antony

    2011-01-01

    The LAMMER kinases are conserved through evolution. They play vital roles in cell growth/differentiation, development, and metabolism. One of the best known functions of the kinases in animal cells is the regulation of pre-mRNA splicing. Kic1 is the LAMMER kinase in fission yeast Schizosaccharomyces pombe. Despite the reported pleiotropic effects of kic1 + deletion/overexpression on various cellular processes the involvement of Kic1 in splicing remains elusive. In this study, we demonstrate for the first time that Kic1 not only is required for efficient splicing but also affects mRNA export, providing evidence for the conserved roles of LAMMER kinases in the unicellular context of fission yeast. Consistent with the hypothesis of its direct participation in multiple steps of pre-mRNA processing, Kic1 is predominantly present in the nucleus during interphase. In addition, the kinase activity of Kic1 plays a role in modulating its own cellular partitioning. Interestingly, Kic1 expression oscillates in a cell cycle-dependent manner and the peak level coincides with mitosis and cytokinesis, revealing a potential mechanism for controlling the kinase activity during the cell cycle. The novel information about the in vivo functions and regulation of Kic1 offers insights into the conserved biological roles fundamental to LAMMER kinases in eukaryotes.

  16. Involvement of the Warburg effect in non-tumor diseases processes.

    Science.gov (United States)

    Chen, Zhe; Liu, Meiqing; Li, Lanfang; Chen, Linxi

    2018-04-01

    Warburg effect, as an energy shift from mitochondrial oxidative phosphorylation to aerobic glycolysis, is extensively found in various cancers. Interestingly, increasing researchers show that Warburg effect plays a crucial role in non-tumor diseases. For instance, inhibition of Warburg effect can alleviate pulmonary vascular remodeling in the process of pulmonary hypertension (PH). Interference of Warburg effect improves mitochondrial function and cardiac function in the process of cardiac hypertrophy and heart failure. Additionally, the Warburg effect induces vascular smooth muscle cell proliferation and contributes to atherosclerosis. Warburg effect may also involve in axonal damage and neuronal death, which are related with multiple sclerosis. Furthermore, Warburg effect significantly promotes cell proliferation and cyst expansion in polycystic kidney disease (PKD). Besides, Warburg effect relieves amyloid β-mediated cell death in Alzheimer's disease. And Warburg effect also improves the mycobacterium tuberculosis infection. Finally, we also introduce some glycolytic agonists. This review focuses on the newest researches about the role of Warburg effect in non-tumor diseases, including PH, tuberculosis, idiopathic pulmonary fibrosis (IPF), failing heart, cardiac hypertrophy, atherosclerosis, Alzheimer's diseases, multiple sclerosis, and PKD. Obviously, Warburg effect may be a potential therapeutic target for those non-tumor diseases. © 2017 Wiley Periodicals, Inc.

  17. Facilitated workshop method to involve stakeholders and public in decision making process in radiological emergencies

    Energy Technology Data Exchange (ETDEWEB)

    Mustonen, Raimo; Sinkko, Kari [STUK-Radiation and Nuclear Safety Authority, Helsinki (Finland). Research and Environmental Surveillance; Haemaelaeinen, Raimo P. [Helsinki Univ. of Technology, Helsinki (Finland). System Analysis Laboratory

    2006-09-15

    International organisations in radiation protection have for many years recommended that key players, e.g. authorities, expert organisations, industry, producers of foodstuffs and even the public, should be involved in the planning of protective actions in case of a nuclear accident. In this work, we have developed and tested a facilitated workshop method where representatives from various fields of the society aim to identify and evaluate systematically protective actions. Decision analysis techniques have been applied in workshops in order to find out the most feasible countermeasure strategies and to make the decision making-process transparent and auditable. The work builds on case studies where it was assumed that a hypothetical accident had led to a release of considerable amounts of radionuclides and therefore various types of countermeasures should be considered. This paper provides experiences gained in several European countries on how to facilitate this kind of workshops and how modern decision analysis techniques can be applied in the decision-making process.

  18. Guidelines for inclusion: Ensuring Indigenous peoples' involvement in water planning processes across South Eastern Australia

    Science.gov (United States)

    Saenz Quitian, Alejandra; Rodríguez, Gloria Amparo

    2016-11-01

    Indigenous peoples within the Murray-Darling Basin have traditionally struggled for the recognition of their cultural, social, environmental, spiritual, commercial and economic connection to the waters that they have traditionally used, as well as their right to engage in all stages of water planning processes. Despite Australian national and federal frameworks providing for the inclusion of Indigenous Australians' objectives in planning frameworks, water plans have rarely addressed these objectives in water, or the strategies to achieve them. Indeed, insufficient resources, a lack of institutional capacity in both Indigenous communities and agencies and an inadequate understanding of Indigenous people's objectives in water management have limited the extent to which Indigenous objectives are addressed in water plans within the Murray-Darling Basin. In this context, the adoption of specific guidelines to meet Indigenous requirements in relation to basin water resources is crucial to support Indigenous engagement in water planning processes. Using insights from participatory planning methods and human rights frameworks, this article outlines a set of alternative and collaborative guidelines to improve Indigenous involvement in water planning and to promote sustainable and just water allocations.

  19. Axillary bud and pericycle involved in the thickening process of the rhizophore nodes in Smilax species

    Directory of Open Access Journals (Sweden)

    B Appezzato-da-Glória

    Full Text Available AbstractThe species of the genus Smilax, popularly known as sarsaparilla, are widely used in folk medicine due to the antirheumatic properties of its underground structures. Smilax fluminensis and S. syphilitica occur in forested areas and form thickened stems called rhizophores from which adventitious roots grow. To provide information for more accurate identification of the commercialised product and for elucidating the process of stem thickening, a morphology and anatomy study of the underground organs of the two species was conducted. The adventitious roots differ in colour and diameter depending on the stage of development. They are white and have a larger diameter in the early stages of development, but as they grow, the adventitious roots become brown and have a smaller diameter due to the disintegration of the epidermis and virtually the entire cortex. In brown roots, the covering function is then performed by the lignified endodermis and the remaining walls of the cells from the last parenchyma cortical layer. These results are similar to those found in studies of other Smilax and suggest that the anatomy of the roots can be useful for identifying fraud in commercialised materials. The thickening process of the nodal regions of the rhizophores in both species involves the activity of axillary buds and pericyclic layers.

  20. Heterologous expression of Pycnoporus cinnabarinus cellobiose dehydrogenase in Pichia pastoris and involvement in saccharification processes

    Directory of Open Access Journals (Sweden)

    Bey Mathieu

    2011-12-01

    Full Text Available Abstract Background Cellobiose dehydrogenase (CDH is an extracellular hemoflavoenzyme produced by lignocellulose-degrading fungi including Pycnoporus cinnabarinus. We investigated the cellulolytic system of P. cinnabarinus, focusing on the involvement of CDH in the deconstruction of lignocellulosic biomass. Results First, P. cinnabarinus growth conditions were optimized for CDH production. Following growth under cellulolytic conditions, the main components secreted were cellulases, xylanases and CDH. To investigate the contribution of P. cinnabarinus secretome in saccharification processes, the Trichoderma reesei enzymatic cocktail was supplemented with the P. cinnabarinus secretome. A significant enhancement of the degradation of wheat straw was observed with (i the production of a large amount of gluconic acid, (ii increased hemicellulose degradation, and (iii increased overall degradation of the lignocellulosic material. P. cinnabarinus CDH was heterologously expressed in Pichia pastoris to obtain large amounts of pure enzyme. In a bioreactor, the recombinant CDH (rCDH expression level reached 7800 U/L. rCDH exhibited values of biochemical parameters similar to those of the natural enzyme, and was able to bind cellulose despite the absence of a carbohydrate-binding module (CBM. Following supplementation of purified rCDH to T. reesei enzymatic cocktail, formation of gluconic acid and increased hemicellulose degradation were observed, thus confirming the previous results observed with P. cinnabarinus secretome. Conclusions We demonstrate that CDH offers an attractive tool for saccharification process enhancement due to gluconic acid production from raw lignocellulosic material.

  1. Facilitated workshop method to involve stakeholders and public in decision making process in radiological emergencies

    International Nuclear Information System (INIS)

    Mustonen, Raimo; Sinkko, Kari; Haemaelaeinen, Raimo P.

    2006-01-01

    International organisations in radiation protection have for many years recommended that key players, e.g. authorities, expert organisations, industry, producers of foodstuffs and even the public, should be involved in the planning of protective actions in case of a nuclear accident. In this work, we have developed and tested a facilitated workshop method where representatives from various fields of the society aim to identify and evaluate systematically protective actions. Decision analysis techniques have been applied in workshops in order to find out the most feasible countermeasure strategies and to make the decision making-process transparent and auditable. The work builds on case studies where it was assumed that a hypothetical accident had led to a release of considerable amounts of radionuclides and therefore various types of countermeasures should be considered. This paper provides experiences gained in several European countries on how to facilitate this kind of workshops and how modern decision analysis techniques can be applied in the decision-making process

  2. Are cognitive "insomnia" processes involved in the development and maintenance of delayed sleep wake phase disorder?

    Science.gov (United States)

    Richardson, Cele E; Gradisar, Michael; Barbero, Sebastian C

    2016-04-01

    Although individuals with delayed sleep wake phase disorder (DSWPD) and chronic insomnia disorder (CID) share many of the same phenomenological experiences, theories relating to the development and maintenance of these disorders are distinct in focus. Unlike CID, theory relating to DSWPD is primarily physiologically based and assumes almost no cognitive pathway. However, recent research findings suggest that individuals with DSWPD also display many of the sleep-disordered cognitive processes that were previously assumed to be unique to the insomnia experience. As such, this review aims to summarise current research findings to address the question "Could cognitive processes be involved in the development and maintenance of DSWPD?" In particular, the presence of cognitive and physiological pre-sleep arousal, sleep-related attentional bias, distorted perception of sleep and daytime functioning, dysfunctional beliefs and safety behaviours will be investigated. As this emerging area of research requires a stronger evidence base, we highlight suggestions for future investigation and provide preliminary practice points for clinicians assessing and treating "insomnia" in patients with DSWPD. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. Analysis of the Proteolytic Processing of ABCA3: Identification of Cleavage Site and Involved Proteases.

    Directory of Open Access Journals (Sweden)

    Nicole Hofmann

    Full Text Available ABCA3 is a lipid transporter in the limiting membrane of lamellar bodies in alveolar type II cells. Mutations in the ABCA3 gene cause respiratory distress syndrome in new-borns and childhood interstitial lung disease. ABCA3 is N-terminally cleaved by an as yet unknown protease, a process believed to regulate ABCA3 activity.The exact site where ABCA3 is cleaved was localized using mass spectrometry (MS. Proteases involved in ABCA3 processing were identified using small molecule inhibitors and siRNA mediated gene knockdown. Results were verified by in vitro digestion of a synthetic peptide substrate mimicking ABCA3's cleavage region, followed by MS analysis.We found that cleavage of ABCA3 occurs after Lys174 which is located in the proteins' first luminal loop. Inhibition of cathepsin L and, to a lesser extent, cathepsin B resulted in attenuation of ABCA3 cleavage. Both enzymes showed activity against the ABCA3 peptide in vitro with cathepsin L being more active.We show here that, like some other proteins of the lysosomal membrane, ABCA3 is a substrate of cathepsin L. Therefore, cathepsin L may represent a potential target to therapeutically influence ABCA3 activity in ABCA3-associated lung disease.

  4. PROCESSES OF ASSIMILATION INVOLVING DENTAL STOP CONSOANTS /t, d/ IN BRASILIAN PORTUGUESE

    Directory of Open Access Journals (Sweden)

    Dermeval da HORA

    2015-06-01

    Full Text Available The major aim of this paper is to present, based on quantitative sociolinguistics, a analyse of the process of progressive assimilation that involve the dental stop consonants. First of all, one overview about the regressive assimilation, which was extensively studied in Brazilian Portuguese, will be present. Then, the contexts of progressive assimilation in the speech community of Itabaiana-PB will be analyzed. The motivation for this paper is the fact that, in the dialect from Itabaiana, the process of progressive assimilation, in words such as muito ‘many/much’ and gosto ‘like”, in which the preceding phonological context exerts influence over the following one, tend to undergo the process of regressive assimilation, such as as pote ‘pot’ and bote ‘boat’, more useful when we think about the Brazilian Portuguese. The theoretical approach underlying the research is the variation theory, or quantitative Sociolinguistics, pioneered by William Labov (1972. The data collected had already been electronically stored in the corpus from Projeto Variação Linguística da Paraíba – VALPB. The sample consists of 36 informants from the community, being stratified according to gender, age group and years of schooling. As result, the computer program Goldvarb (SANKOFF; TAGLIAMONTE; SMITH, 2005 pointed as favorite to the application of the rule: the gender (male gender, the level of schooling (no scholar historic since the primary, the following phonological context (high back vowel, the precedent phonological context (monophthong, and the tonicity (post-stressed syllable.

  5. Levels of processing in working memory: differential involvement of frontotemporal networks.

    Science.gov (United States)

    Rose, Nathan S; Craik, Fergus I M; Buchsbaum, Bradley R

    2015-03-01

    How does the brain maintain to-be-remembered information in working memory (WM), particularly when the focus of attention is drawn to processing other information? Cognitive models of WM propose that when items are displaced from focal attention recall involves retrieval from long-term memory (LTM). In this fMRI study, we tried to clarify the role of LTM in performance on a WM task and the type of representation that is used to maintain an item in WM during rehearsal-filled versus distractor-filled delays. Participants made a deep or shallow levels-of-processing (LOP) decision about a single word at encoding and tried to recall the word after a delay filled with either rehearsal of the word or a distracting math task. Recalling one word after 10 sec of distraction demonstrated behavioral and neural indices of retrieval from LTM (i.e., LOP effects and medial-temporal lobe activity). In contrast, recall after rehearsal activated cortical areas that reflected reporting the word from focal attention. In addition, areas that showed an LOP effect at encoding (e.g., left ventrolateral VLPFC and the anterior temporal lobes [ATLs]) were reactivated at recall, especially when recall followed distraction. Moreover, activity in left VLPFC during encoding, left ATL during the delay, and left hippocampus during retrieval predicted recall success after distraction. Whereas shallow LOP and rehearsal-related areas supported active maintenance of one item in focal attention, the behavioral processes and neural substrates that support LTM supported recall of one item after it was displaced from focal attention.

  6. Nonlinear Optical Spectroscopy in the Time Domain: Studies of Ultrafast Molecular Processes in the Condensed Phase.

    Science.gov (United States)

    Joo, Taiha

    Ultrafast molecular processes in the condensed phase at room temperature are studied in the time domain by four wave mixing spectroscopy. The structure/dynamics of various quantum states can be studied by varying the time ordering of the incident fields, their polarization, their colors, etc. In one, time-resolved coherent Stokes Raman spectroscopy of benzene is investigated at room temperature. The reorientational correlation time of benzene as well as the T_2 time of the nu _1 ring-breathing mode have been measured by using two different polarization geometries. Bohr frequency difference beats have also been resolved between the nu_1 modes of ^ {12}C_6H_6 and ^{12}C_5^{13 }CH_6.. The dephasing dynamics of the nu _1 ring-breathing mode of neat benzene is studied by time-resolved coherent anti-Stokes Raman scattering. Ultrafast time resolution reveals deviation from the conventional exponential decay. The correlation time, tau _{rm c}, and the rms magnitude, Delta, of the Bohr frequency modulation are determined for the process responsible for the vibrational dephasing by Kubo dephasing function analysis. The electronic dephasing of two oxazine dyes in ethylene glycol at room temperature is investigated by photon echo experiments. It was found that at least two stochastic processes are responsible for the observed electronic dephasing. Both fast (homogeneous) and slow (inhomogeneous) dynamics are recovered using Kubo line shape analysis. Moreover, the slow dynamics is found to spectrally diffuse over the inhomogeneous distribution on the time scale around a picosecond. Time-resolved degenerate four wave mixing signal of dyes in a population measurement geometry is reported. The vibrational coherences both in the ground and excited electronic states produced strong oscillations in the signal together with the usual population decay from the excited electronic state. Absolute frequencies and their dephasing times of the vibrational modes at ~590 cm^{-1} are obtained

  7. NONLINEAR WAVE INTERACTIONS AS EMISSION PROCESS OF TYPE II RADIO BURSTS

    Energy Technology Data Exchange (ETDEWEB)

    Ganse, Urs; Kilian, Patrick; Spanier, Felix [Lehrstuhl fuer Astronomie, Universitaet Wuerzburg, Wuerzburg (Germany); Vainio, Rami, E-mail: uganse@astro.uni-wuerzburg.de [Department of Physics, University of Helsinki, Helsinki (Finland)

    2012-06-01

    The emission of fundamental and harmonic frequency radio waves of type II radio bursts are assumed to be products of three-wave interaction processes of beam-excited Langmuir waves. Using a particle-in-cell code, we have performed simulations of the assumed emission region, a coronal mass ejection foreshock with two counterstreaming electron beams. Analysis of wavemodes within the simulation shows self-consistent excitation of beam-driven modes, which yield interaction products at both fundamental and harmonic emission frequencies. Through variation of the beam strength, we have investigated the dependence of energy transfer into electrostatic and electromagnetic modes, confirming the quadratic dependence of electromagnetic emission on electron beam strength.

  8. NONLINEAR WAVE INTERACTIONS AS EMISSION PROCESS OF TYPE II RADIO BURSTS

    International Nuclear Information System (INIS)

    Ganse, Urs; Kilian, Patrick; Spanier, Felix; Vainio, Rami

    2012-01-01

    The emission of fundamental and harmonic frequency radio waves of type II radio bursts are assumed to be products of three-wave interaction processes of beam-excited Langmuir waves. Using a particle-in-cell code, we have performed simulations of the assumed emission region, a coronal mass ejection foreshock with two counterstreaming electron beams. Analysis of wavemodes within the simulation shows self-consistent excitation of beam-driven modes, which yield interaction products at both fundamental and harmonic emission frequencies. Through variation of the beam strength, we have investigated the dependence of energy transfer into electrostatic and electromagnetic modes, confirming the quadratic dependence of electromagnetic emission on electron beam strength.

  9. Multi input single output model predictive control of non-linear bio-polymerization process

    Energy Technology Data Exchange (ETDEWEB)

    Arumugasamy, Senthil Kumar; Ahmad, Z. [School of Chemical Engineering, Univerisiti Sains Malaysia, Engineering Campus, Seri Ampangan,14300 Nibong Tebal, Seberang Perai Selatan, Pulau Pinang (Malaysia)

    2015-05-15

    This paper focuses on Multi Input Single Output (MISO) Model Predictive Control of bio-polymerization process in which mechanistic model is developed and linked with the feedforward neural network model to obtain a hybrid model (Mechanistic-FANN) of lipase-catalyzed ring-opening polymerization of ε-caprolactone (ε-CL) for Poly (ε-caprolactone) production. In this research, state space model was used, in which the input to the model were the reactor temperatures and reactor impeller speeds and the output were the molecular weight of polymer (M{sub n}) and polymer polydispersity index. State space model for MISO created using System identification tool box of Matlab™. This state space model is used in MISO MPC. Model predictive control (MPC) has been applied to predict the molecular weight of the biopolymer and consequently control the molecular weight of biopolymer. The result shows that MPC is able to track reference trajectory and give optimum movement of manipulated variable.

  10. Self-Organized Criticality in Astrophysics The Statistics of Nonlinear Processes in the Universe

    CERN Document Server

    Aschwanden, Markus

    2011-01-01

    The concept of ‘self-organized criticality’ (SOC) has been applied to a variety of problems, ranging from population growth and traffic jams to earthquakes, landslides and forest fires. The technique is now being applied to a wide range of phenomena in astrophysics, such as planetary magnetospheres, solar flares, cataclysmic variable stars, accretion disks, black holes and gamma-ray bursts, and also to phenomena in galactic physics and cosmology. Self-organized Criticality in Astrophysics introduces the concept of SOC and shows that, due to its universality and ubiquity, it is a law of nature. The theoretical framework and specific physical models are described, together with a range of applications in various aspects of astrophyics. The mathematical techniques, including the statistics of random processes, time series analysis, time scale and waiting time distributions, are presented and the results are applied to specific observations of astrophysical phenomena.

  11. All-Optical Signal processing using Highly Nonlinear Photonic Crystal Fiber

    DEFF Research Database (Denmark)

    Andersen, Peter Andreas

    2006-01-01

    -optical regeneration is the only possible way of regenerating a signal with the current technology. Transforming the current telecommunication network into an all-optical network will require an all-optical regeneration of the optical signal. At the current time (May 2005) all-optical regeneration is a tool only used......The use of HNL-PCF in optical communication systems has been investigated in this thesis. The investigation has been done with respect to the future of telecommunications in an all-optical system. The PCFs used have all been used for all-optical signal processing as part of an optical component...... and the possibility of large differences between the refractive indices of the core and the cladding by using air-holes, makes PCFs suited for custom made components. By testing a HNL-PCF as a medium for supercontinuum generation at various dispersion values and at the same time using that supercontinuum...

  12. Involvement of α2-adrenoceptors in inhibitory and facilitatory pain modulation processes.

    Science.gov (United States)

    Vo, L; Drummond, P D

    2016-03-01

    In healthy humans, high-frequency electrical stimulation (HFS) of the forearm not only produces hyperalgesia at the site of stimulation but also reduces sensitivity to pressure-pain on the ipsilateral side of the forehead. In addition, HFS augments the ipsilateral trigeminal nociceptive blink reflex and intensifies the ipsilateral component of conditioned pain modulation. The aim of this study was to determine whether α2-adrenoceptors mediate these ipsilateral nociceptive influences. The α2-adrenoceptor antagonist yohimbine was administered to 22 participants in a double-blind, placebo-controlled crossover study. In each session, thermal and mechanical sensitivity in the forearms and forehead was assessed before and after HFS. In addition, the combined effect of HFS and yohimbine on the nociceptive blink reflex and on conditioned pain modulation was explored. In this paradigm, the conditioning stimulus was cold pain in the ipsilateral or contralateral temple, and the test stimulus was electrically evoked pain in the forearm. Blood pressure and electrodermal activity increased for several hours after yohimbine administration, consistent with blockade of central α2-adrenoceptors. Yohimbine not only augmented the nociceptive blink reflex ipsilateral to HFS but also intensified the inhibitory influence of ipsilateral temple cooling on electrically evoked pain at the HFS-treated site in the forearm. Yohimbine had no consistent effect on primary or secondary hyperalgesia in the forearm or on pressure-pain in the ipsilateral forehead. These findings imply involvement of α2-adrenoceptors both in ipsilateral antinociceptive and pronociceptive pain modulation processes. However, a mechanism not involving α2-adrenoceptors appears to mediate analgesia in the ipsilateral forehead after HFS. © 2015 European Pain Federation - EFIC®

  13. Forest Soil Bacteria: Diversity, Involvement in Ecosystem Processes, and Response to Global Change.

    Science.gov (United States)

    Lladó, Salvador; López-Mondéjar, Rubén; Baldrian, Petr

    2017-06-01

    The ecology of forest soils is an important field of research due to the role of forests as carbon sinks. Consequently, a significant amount of information has been accumulated concerning their ecology, especially for temperate and boreal forests. Although most studies have focused on fungi, forest soil bacteria also play important roles in this environment. In forest soils, bacteria inhabit multiple habitats with specific properties, including bulk soil, rhizosphere, litter, and deadwood habitats, where their communities are shaped by nutrient availability and biotic interactions. Bacteria contribute to a range of essential soil processes involved in the cycling of carbon, nitrogen, and phosphorus. They take part in the decomposition of dead plant biomass and are highly important for the decomposition of dead fungal mycelia. In rhizospheres of forest trees, bacteria interact with plant roots and mycorrhizal fungi as commensalists or mycorrhiza helpers. Bacteria also mediate multiple critical steps in the nitrogen cycle, including N fixation. Bacterial communities in forest soils respond to the effects of global change, such as climate warming, increased levels of carbon dioxide, or anthropogenic nitrogen deposition. This response, however, often reflects the specificities of each studied forest ecosystem, and it is still impossible to fully incorporate bacteria into predictive models. The understanding of bacterial ecology in forest soils has advanced dramatically in recent years, but it is still incomplete. The exact extent of the contribution of bacteria to forest ecosystem processes will be recognized only in the future, when the activities of all soil community members are studied simultaneously. Copyright © 2017 American Society for Microbiology.

  14. Development of brain networks involved in spoken word processing of Mandarin Chinese.

    Science.gov (United States)

    Cao, Fan; Khalid, Kainat; Lee, Rebecca; Brennan, Christine; Yang, Yanhui; Li, Kuncheng; Bolger, Donald J; Booth, James R

    2011-08-01

    Developmental differences in phonological and orthographic processing of Chinese spoken words were examined in 9-year-olds, 11-year-olds and adults using functional magnetic resonance imaging (fMRI). Rhyming and spelling judgments were made to two-character words presented sequentially in the auditory modality. Developmental comparisons between adults and both groups of children combined showed that age-related changes in activation in visuo-orthographic regions depended on a task. There were developmental increases in the left inferior temporal gyrus and the right inferior occipital gyrus in the spelling task, suggesting more extensive visuo-orthographic processing in a task that required access to these representations. Conversely, there were developmental decreases in activation in the left fusiform gyrus and left middle occipital gyrus in the rhyming task, suggesting that the development of reading is marked by reduced involvement of orthography in a spoken language task that does not require access to these orthographic representations. Developmental decreases may arise from the existence of extensive homophony (auditory words that have multiple spellings) in Chinese. In addition, we found that 11-year-olds and adults showed similar activation in the left superior temporal gyrus across tasks, with both groups showing greater activation than 9-year-olds. This pattern suggests early development of perceptual representations of phonology. In contrast, 11-year-olds and 9-year-olds showed similar activation in the left inferior frontal gyrus across tasks, with both groups showing weaker activation than adults. This pattern suggests late development of controlled retrieval and selection of lexical representations. Altogether, this study suggests differential effects of character acquisition on development of components of the language network in Chinese as compared to previous reports on alphabetic languages. Published by Elsevier Inc.

  15. Involvement of the visual change detection process in facilitating perceptual alternation in the bistable image.

    Science.gov (United States)

    Urakawa, Tomokazu; Bunya, Mao; Araki, Osamu

    2017-08-01

    A bistable image induces one of two perceptual alternatives. When the bistable visual image is continuously viewed, the percept of the image alternates from one possible percept to the other. Perceptual alternation was previously reported to be induced by an exogenous perturbation in the bistable image, and this perturbation was theoretically interpreted to cause neural noise, prompting a transition between two stable perceptual states. However, little is known experimentally about the visual processing of exogenously driven perceptual alternation. Based on the findings of a previous behavioral study (Urakawa et al. in Perception 45:474-482, 2016), the present study hypothesized that the automatic visual change detection process, which is relevant to the detection of a visual change in a sequence of visual events, has an enhancing effect on the induction of perceptual alternation, similar to neural noise. In order to clarify this issue, we developed a novel experimental paradigm in which visual mismatch negativity (vMMN), an electroencephalographic brain response that reflects visual change detection, was evoked while participants continuously viewed the bistable image. In terms of inter-individual differences in neural and behavioral data, we found that enhancements in the peak amplitude of vMMN1, early vMMN at a latency of approximately 150 ms, correlated with increases in the proportion of perceptual alternation across participants. Our results indicate the involvement of automatic visual change detection in the induction of perceptual alternation, similar to neural noise, thereby providing a deeper insight into the neural mechanisms underlying exogenously driven perceptual alternation in the bistable image.

  16. Priorities for methodological research on patient and public involvement in clinical trials: A modified Delphi process.

    Science.gov (United States)

    Kearney, Anna; Williamson, Paula; Young, Bridget; Bagley, Heather; Gamble, Carrol; Denegri, Simon; Muir, Delia; Simon, Natalie A; Thomas, Stephen; Elliot, Jim T; Bulbeck, Helen; Crocker, Joanna C; Planner, Claire; Vale, Claire; Clarke, Mike; Sprosen, Tim; Woolfall, Kerry

    2017-12-01

    Despite increasing international interest, there is a lack of evidence about the most efficient, effective and acceptable ways to implement patient and public involvement (PPI) in clinical trials. To identify the priorities of UK PPI stakeholders for methodological research to help resolve uncertainties about PPI in clinical trials. A modified Delphi process including a two round online survey and a stakeholder consensus meeting. In total, 237 people registered of whom 219 (92%) completed the first round. One hundred and eighty-seven of 219 (85%) completed the second; 25 stakeholders attended the consensus meeting. Round 1 of the survey comprised 36 topics; 42 topics were considered in round 2 and at the consensus meeting. Approximately 96% of meeting participants rated the top three topics as equally important. These were as follows: developing strong and productive working relationships between researchers and PPI contributors; exploring PPI practices in selecting trial outcomes of importance to patients; and a systematic review of PPI activity to improve the accessibility and usefulness of trial information (eg participant information sheets) for participants. The prioritized methodological research topics indicate important areas of uncertainty about PPI in trials. Addressing these uncertainties will be critical to enhancing PPI. Our findings should be used in the planning and funding of PPI in clinical trials to help focus research efforts and minimize waste. © 2017 The Authors Health Expectations Published by John Wiley & Sons Ltd.

  17. Involvement of mast cells by the malignant process in patients with Philadelphia chromosome negative myeloproliferative neoplasms.

    Science.gov (United States)

    Wang, J; Ishii, T; Zhang, W; Sozer, S; Dai, Y; Mascarenhas, J; Najfeld, V; Zhao, Z J; Hoffman, R; Wisch, N; Xu, M

    2009-09-01

    The Philadelphia chromosome negative myeloproliferative neoplasms (MPNs) are clonal hematologic malignancies frequently characterized by a mutation in JAK2 (JAK2V617F). Peripheral blood (PB) CD34(+) cells from patients with polycythemia vera (PV) and primary myelofibrosis (PMF) generated in vitro significantly fewer mast cells (MCs) than normal PB CD34(+) cells. The numbers of MC progenitors assayed from MPN CD34(+) cells were, however, similar to that assayed from normal CD34(+) cells. A higher percentage of the cultured MPN MCs expressed FcvarepsilonRIalpha, CD63 and CD69 than normal MCs, suggesting that cultured MPN MCs are associated with an increased state of MC activation. Further analysis showed that a higher proportion of cultured PV and PMF MCs underwent apoptosis in vitro. By using JAK2V617F, MplW515L and chromosomal abnormalities as clonality markers, we showed that the malignant process involved MPN MCs. JAK2V617F-positive MC colonies were assayable from the PB CD34(+) cells of each of the 17 JAK2V617F positive MPN patients studied. Furthermore, erlotinib, a JAK2 inhibitor, was able to inhibit JAK2V617F-positive PV MC progenitor cells, indicating that malignant MC progenitor cells are a potential cellular target for such JAK2 inhibitor-directed therapy.

  18. Sum rules across the unpolarized Compton processes involving generalized polarizabilities and moments of nucleon structure functions

    Science.gov (United States)

    Lensky, Vadim; Hagelstein, Franziska; Pascalutsa, Vladimir; Vanderhaeghen, Marc

    2018-04-01

    We derive two new sum rules for the unpolarized doubly virtual Compton scattering process on a nucleon, which establish novel low-Q2 relations involving the nucleon's generalized polarizabilities and moments of the nucleon's unpolarized structure functions F1(x ,Q2) and F2(x ,Q2). These relations facilitate the determination of some structure constants which can only be accessed in off-forward doubly virtual Compton scattering, not experimentally accessible at present. We perform an empirical determination for the proton and compare our results with a next-to-leading-order chiral perturbation theory prediction. We also show how these relations may be useful for a model-independent determination of the low-Q2 subtraction function in the Compton amplitude, which enters the two-photon-exchange contribution to the Lamb shift of (muonic) hydrogen. An explicit calculation of the Δ (1232 )-resonance contribution to the muonic-hydrogen 2 P -2 S Lamb shift yields -1 ±1 μ eV , confirming the previously conjectured smallness of this effect.

  19. Topological approximation of the nonlinear Anderson model

    Science.gov (United States)

    Milovanov, Alexander V.; Iomin, Alexander

    2014-06-01

    We study the phenomena of Anderson localization in the presence of nonlinear interaction on a lattice. A class of nonlinear Schrödinger models with arbitrary power nonlinearity is analyzed. We conceive the various regimes of behavior, depending on the topology of resonance overlap in phase space, ranging from a fully developed chaos involving Lévy flights to pseudochaotic dynamics at the onset of delocalization. It is demonstrated that the quadratic nonlinearity plays a dynamically very distinguished role in that it is the only type of power nonlinearity permitting an abrupt localization-delocalization transition with unlimited spreading already at the delocalization border. We describe this localization-delocalization transition as a percolation transition on the infinite Cayley tree (Bethe lattice). It is found in the vicinity of the criticality that the spreading of the wave field is subdiffusive in the limit t →+∞. The second moment of the associated probability distribution grows with time as a power law ∝ tα, with the exponent α =1/3 exactly. Also we find for superquadratic nonlinearity that the analog pseudochaotic regime at the edge of chaos is self-controlling in that it has feedback on the topology of the structure on which the transport processes concentrate. Then the system automatically (without tuning of parameters) develops its percolation point. We classify this type of behavior in terms of self-organized criticality dynamics in Hilbert space. For subquadratic nonlinearities, the behavior is shown to be sensitive to the details of definition of the nonlinear term. A transport model is proposed based on modified nonlinearity, using the idea of "stripes" propagating the wave process to large distances. Theoretical investigations, presented here, are the basis for consistency analysis of the different localization-delocalization patterns in systems with many coupled degrees of freedom in association with the asymptotic properties of the

  20. An Estimation of a Nonlinear Dynamic Process Using Latent Class Extended Mixed Models: Affect Profiles After Terrorist Attacks.

    Science.gov (United States)

    Burro, Roberto; Raccanello, Daniela; Pasini, Margherita; Brondino, Margherita

    2018-01-01

    Conceptualizing affect as a complex nonlinear dynamic process, we used latent class extended mixed models (LCMM) to understand whether there were unobserved groupings in a dataset including longitudinal measures. Our aim was to identify affect profiles over time in people vicariously exposed to terrorism, studying their relations with personality traits. The participants were 193 university students who completed online measures of affect during the seven days following two terrorist attacks (Paris, November 13, 2015; Brussels, March 22, 2016); Big Five personality traits; and antecedents of affect. After selecting students whose negative affect was influenced by the two attacks (33%), we analysed the data with the LCMM package of R. We identified two affect profiles, characterized by different trends over time: The first profile comprised students with lower positive affect and higher negative affect compared to the second profile. Concerning personality traits, conscientious-ness was lower for the first profile compared to the second profile, and vice versa for neuroticism. Findings are discussed for both their theoretical and applied relevance.

  1. An Investigation into the Involvement of California Central Valley High School Students with Disabilities in the IEP Process

    Science.gov (United States)

    Anderson, Cheryle Ann

    2012-01-01

    The purpose of this study was to investigate the involvement of California Central Valley high school students with disabilities in the Individual Education Plan (IEP) process. Specifically, this study investigated the involvement of students with disabilities in the development of the IEP and IEP meetings. In addition, this study explored the…

  2. Linear and nonlinear dynamics of heart rate variability in the process of exposure to 3600 m in 10 min.

    Science.gov (United States)

    Zhang, Da; She, Jin; Yang, Jun; Yu, Mengsun

    2015-06-01

    Acute hypoxia activates several autonomic mechanisms, mainly in cardiovascular system and respiratory system. The influence of acute hypoxia on linear and nonlinear heart rate variability (HRV) has been studied, but the parameters in the process of hypoxia are still unclear. Although the changes of HRV in frequency domain are related to autonomic responses, how nonlinear dynamics change with the decrease of ambient atmospheric pressure is unknown either. Eight healthy male subjects were exposed to simulated altitude from sea level to 3600 m in 10 min. HRV parameters in frequency domain were analyzed by wavelet packet transform (Daubechies 4, 4 level) followed by Hilbert transform to assess the spectral power of modified low frequency (0.0625-0.1875 Hz, LFmod), modified high frequency (0.1875-0.4375 Hz, HFmod), and the LFmod/HFmod ratio in every 1 min. Nonlinear parameters were also quantified by sample entropy (SampEn) and short term fractal correlation exponent (α1) in the process. Hypoxia was associated with the depression of both LFmod and HFmod component. They were significantly lower than that at sea level at 3600 m and 2880 m respectively (both p nonlinear HRV parameters continuously in the process of hypoxia would be an effective way to evaluate the different regulatory mechanisms of autonomic nervous system.

  3. Nonlinear optics at interfaces

    International Nuclear Information System (INIS)

    Chen, C.K.

    1980-12-01

    Two aspects of surface nonlinear optics are explored in this thesis. The first part is a theoretical and experimental study of nonlinear intraction of surface plasmons and bulk photons at metal-dielectric interfaces. The second part is a demonstration and study of surface enhanced second harmonic generation at rough metal surfaces. A general formulation for nonlinear interaction of surface plasmons at metal-dielectric interfaces is presented and applied to both second and third order nonlinear processes. Experimental results for coherent second and third harmonic generation by surface plasmons and surface coherent antiStokes Raman spectroscopy (CARS) are shown to be in good agreement with the theory

  4. Cellular distribution and function of ion channels involved in transport processes in rat tracheal epithelium.

    Science.gov (United States)

    Hahn, Anne; Faulhaber, Johannes; Srisawang, Lalita; Stortz, Andreas; Salomon, Johanna J; Mall, Marcus A; Frings, Stephan; Möhrlen, Frank

    2017-06-01

    Transport of water and electrolytes in airway epithelia involves chloride-selective ion channels, which are controlled either by cytosolic Ca 2+ or by cAMP The contributions of the two pathways to chloride transport differ among vertebrate species. Because rats are becoming more important as animal model for cystic fibrosis, we have examined how Ca 2+ - dependent and cAMP- dependent Cl - secretion is organized in the rat tracheal epithelium. We examined the expression of the Ca 2+ -gated Cl - channel anoctamin 1 (ANO1), the cystic fibrosis transmembrane conductance regulator (CFTR) Cl - channel, the epithelial Na + channel ENaC, and the water channel aquaporin 5 (AQP5) in rat tracheal epithelium. The contribution of ANO1 channels to nucleotide-stimulated Cl - secretion was determined using the channel blocker Ani9 in short-circuit current recordings obtained from primary cultures of rat tracheal epithelial cells in Ussing chambers. We found that ANO1, CFTR and AQP5 proteins were expressed in nonciliated cells of the tracheal epithelium, whereas ENaC was expressed in ciliated cells. Among nonciliated cells, ANO1 occurred together with CFTR and Muc5b and, in addition, in a different cell type without CFTR and Muc5b. Bioelectrical studies with the ANO1-blocker Ani9 indicated that ANO1 mediated the secretory response to the nucleotide uridine-5'-triphosphate. Our data demonstrate that, in rat tracheal epithelium, Cl - secretion and Na + absorption are routed through different cell types, and that ANO1 channels form the molecular basis of Ca 2+ -dependent Cl - secretion in this tissue. These characteristic features of Cl - -dependent secretion reveal similarities and distinct differences to secretory processes in human airways. © 2017 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

  5. Multiple factors and processes involved in host cell killing by bacteriophage Mu: characterization and mapping.

    Science.gov (United States)

    Waggoner, B T; Marrs, C F; Howe, M M; Pato, M L

    1984-07-15

    The regions of bacteriophage Mu involved in host cell killing were determined by infection of a lambda-immune host with 12 lambda pMu-transducing phages carrying different amounts of Mu DNA beginning at the left end. Infecting lambda pMu phages containing 5.0 (+/- 0.2) kb or less of the left end of Mu DNA did not kill the lambda-immune host, whereas lambda pMu containing 5.1 kb did kill, thus locating the right end of the kil gene between approximately 5.0 and 5.1 kb. For the Kil+ phages the extent of killing increased as the multiplicity of infection (m.o.i.) increased. In addition, killing was also affected by the presence of at least two other regions of Mu DNA: one, located between 5.1 and 5.8 kb, decreased the extent of killing; the other, located between 6.3 and 7.9 kb, greatly increased host cell killing. Killing was also assayed after lambda pMu infection of a lambda-immune host carrying a mini-Mu deleted for most of the B gene and the middle region of Mu DNA. Complementation of mini-Mu replication by infecting B+ lambda pMu phages resulted in killing of the lambda-immune, mini-Mu-containing host, regardless of the presence or absence of the Mu kil gene. The extent of host cell killing increased as the m.o.i. of the infecting lambda pMu increased, and was further enhanced by both the presence of the kil gene and the region located between 6.3 and 7.9 kb. These distinct processes of kil-mediated killing in the absence of replication and non-kil-mediated killing in the presence of replication were also observed after induction of replication-deficient and kil mutant prophages, respectively.

  6. Platelet-activating factor acether (PAF-acether) involvement in acute inflammatory and pain processes.

    Science.gov (United States)

    Bonnet, J; Loiseau, A M; Orvoen, M; Bessin, P

    1981-12-01

    PAF-acether is a potent aggregating agent released by various cells involved in acute inflammatory process. In this paper, exogenous PAF-acether has been investigated for its ability to generate signs of inflammation (edema measured by plethysmometry) and hyperalgesia (Randall-Sellito test) by standard subplantar injection in the rat paw. From 0.005 microgram. PAF-acether induced significant edema of the paw, maximal 1 hour after injection; it was dose-dependent from 0.1 to 5 microgram. Significant dose-dependent hyperalgesia occurred from 1.25 microgram; it reached a plateau from 2 to 4 hours after injection. Both phenomena were long-lasting (greater than 6 h). PAF-acether was 1.5 to 10 times stronger than PGI2 and PGE2 in inducing edema, pain, and in increasing vascular permeability. We investigated the interaction of miscellaneous drugs with the edema and the hyperalgesia caused by 2.5 microgram of PAF-acether. Non-steroidal anti-inflammatory (NSAI) drugs exerted only moderate effects on the edema without affecting hyperalgesia. Edema was highly reduced by various agents: prednisolone, L-cysteine, anti-calcic drugs, theophylline, PGI2, salbutamol, clonidine. All of them, except clonidine, and in contrast to NSAI drugs, were more potent on PAF-acether edema than on kaolin edema; a possible link between these agents is their ability to increase cyclic AMP levels in the cells and consequently to reduce lysosomal enzyme release. PAF-acether itself, injected intra-peritoneally, inhibited PAF-acether edema without preventing pain, at doses inactive on arterial pressure and hematocrit, but inducing marked gastric mucosal damage. Among the drugs tested, including analgesics, only PGI2 and imidazole improved PAF-induced hyperalgesia, showing a dissociation between edema and hyperalgesia not only in their induction (doses of PAF required, time course of the phenomena), but in the drugs able to antagonize their development too.

  7. [Motor capacities involved in the psychomotor skills of the cardiopulmonary resuscitation technique: recommendations for the teaching-learning process].

    Science.gov (United States)

    Miyadahira, A M

    2001-12-01

    It is a bibliographic study about the identification of the motor capacities involved in the psychomotor skills of the cardiopulmonary resuscitation (CPR) which aims to obtain subsidies to the planning of the teaching-learning process of this skill. It was found that: the motor capacities involved in the psychomotor skill of the CPR technique are predominantly cognitive and motor, involving 9 perceptive-motor capacities and 8 physical proficiency capacities. The CPR technique is a psychomotor skill classified as open, done in series and categorized as a thin and global skill and the teaching-learning process of the CPR technique has an elevated degree of complexity.

  8. Nonlinear optics

    International Nuclear Information System (INIS)

    Boyd, R.W.

    1992-01-01

    Nonlinear optics is the study of the interaction of intense laser light with matter. This book is a textbook on nonlinear optics at the level of a beginning graduate student. The intent of the book is to provide an introduction to the field of nonlinear optics that stresses fundamental concepts and that enables the student to go on to perform independent research in this field. This book covers the areas of nonlinear optics, quantum optics, quantum electronics, laser physics, electrooptics, and modern optics

  9. 29 CFR 570.61 - Occupations in the operation of power-driven meat-processing machines and occupations involving...

    Science.gov (United States)

    2010-07-01

    ..., for example, the slicing in a retail delicatessen of meat, poultry, seafood, bread, vegetables, or.... This section shall not apply to: (1) The killing and processing of poultry, rabbits, or small game in... and occupations involving slaughtering, meat and poultry packing, processing, or rendering (Order 10...

  10. Degenerate nonlinear diffusion equations

    CERN Document Server

    Favini, Angelo

    2012-01-01

    The aim of these notes is to include in a uniform presentation style several topics related to the theory of degenerate nonlinear diffusion equations, treated in the mathematical framework of evolution equations with multivalued m-accretive operators in Hilbert spaces. The problems concern nonlinear parabolic equations involving two cases of degeneracy. More precisely, one case is due to the vanishing of the time derivative coefficient and the other is provided by the vanishing of the diffusion coefficient on subsets of positive measure of the domain. From the mathematical point of view the results presented in these notes can be considered as general results in the theory of degenerate nonlinear diffusion equations. However, this work does not seek to present an exhaustive study of degenerate diffusion equations, but rather to emphasize some rigorous and efficient techniques for approaching various problems involving degenerate nonlinear diffusion equations, such as well-posedness, periodic solutions, asympt...

  11. Socialization Values and Parenting Practices as Predictors of Parental Involvement in Their Children's Educational Process

    NARCIS (Netherlands)

    Kikas, Eve; Tulviste, Tiia; Peets, Kätlin

    2014-01-01

    Research Findings: The purpose of this study was to examine associations between parental socialization values (including inconsistency in values), parenting practices, and parental involvement in their children's education. Altogether 242 Estonian mothers and fathers of first-grade children

  12. Nonlinear optics

    CERN Document Server

    Bloembergen, Nicolaas

    1996-01-01

    Nicolaas Bloembergen, recipient of the Nobel Prize for Physics (1981), wrote Nonlinear Optics in 1964, when the field of nonlinear optics was only three years old. The available literature has since grown by at least three orders of magnitude.The vitality of Nonlinear Optics is evident from the still-growing number of scientists and engineers engaged in the study of new nonlinear phenomena and in the development of new nonlinear devices in the field of opto-electronics. This monograph should be helpful in providing a historical introduction and a general background of basic ideas both for expe

  13. Intramolecular and nonlinear dynamics

    Energy Technology Data Exchange (ETDEWEB)

    Davis, M.J. [Argonne National Laboratory, IL (United States)

    1993-12-01

    Research in this program focuses on three interconnected areas. The first involves the study of intramolecular dynamics, particularly of highly excited systems. The second area involves the use of nonlinear dynamics as a tool for the study of molecular dynamics and complex kinetics. The third area is the study of the classical/quantum correspondence for highly excited systems, particularly systems exhibiting classical chaos.

  14. Perspectives on Nonlinear Filtering

    KAUST Repository

    Law, Kody

    2015-01-01

    The solution to the problem of nonlinear filtering may be given either as an estimate of the signal (and ideally some measure of concentration), or as a full posterior distribution. Similarly, one may evaluate the fidelity of the filter either by its ability to track the signal or its proximity to the posterior filtering distribution. Hence, the field enjoys a lively symbiosis between probability and control theory, and there are plenty of applications which benefit from algorithmic advances, from signal processing, to econometrics, to large-scale ocean, atmosphere, and climate modeling. This talk will survey some recent theoretical results involving accurate signal tracking with noise-free (degenerate) dynamics in high-dimensions (infinite, in principle, but say d between 103 and 108 , depending on the size of your application and your computer), and high-fidelity approximations of the filtering distribution in low dimensions (say d between 1 and several 10s).

  15. Perspectives on Nonlinear Filtering

    KAUST Repository

    Law, Kody

    2015-01-07

    The solution to the problem of nonlinear filtering may be given either as an estimate of the signal (and ideally some measure of concentration), or as a full posterior distribution. Similarly, one may evaluate the fidelity of the filter either by its ability to track the signal or its proximity to the posterior filtering distribution. Hence, the field enjoys a lively symbiosis between probability and control theory, and there are plenty of applications which benefit from algorithmic advances, from signal processing, to econometrics, to large-scale ocean, atmosphere, and climate modeling. This talk will survey some recent theoretical results involving accurate signal tracking with noise-free (degenerate) dynamics in high-dimensions (infinite, in principle, but say d between 103 and 108 , depending on the size of your application and your computer), and high-fidelity approximations of the filtering distribution in low dimensions (say d between 1 and several 10s).

  16. Active pharmaceutical ingredient (API) production involving continuous processes--a process system engineering (PSE)-assisted design framework.

    Science.gov (United States)

    Cervera-Padrell, Albert E; Skovby, Tommy; Kiil, Søren; Gani, Rafiqul; Gernaey, Krist V

    2012-10-01

    A systematic framework is proposed for the design of continuous pharmaceutical manufacturing processes. Specifically, the design framework focuses on organic chemistry based, active pharmaceutical ingredient (API) synthetic processes, but could potentially be extended to biocatalytic and fermentation-based products. The method exploits the synergic combination of continuous flow technologies (e.g., microfluidic techniques) and process systems engineering (PSE) methods and tools for faster process design and increased process understanding throughout the whole drug product and process development cycle. The design framework structures the many different and challenging design problems (e.g., solvent selection, reactor design, and design of separation and purification operations), driving the user from the initial drug discovery steps--where process knowledge is very limited--toward the detailed design and analysis. Examples from the literature of PSE methods and tools applied to pharmaceutical process design and novel pharmaceutical production technologies are provided along the text, assisting in the accumulation and interpretation of process knowledge. Different criteria are suggested for the selection of batch and continuous processes so that the whole design results in low capital and operational costs as well as low environmental footprint. The design framework has been applied to the retrofit of an existing batch-wise process used by H. Lundbeck A/S to produce an API: zuclopenthixol. Some of its batch operations were successfully converted into continuous mode, obtaining higher yields that allowed a significant simplification of the whole process. The material and environmental footprint of the process--evaluated through the process mass intensity index, that is, kg of material used per kg of product--was reduced to half of its initial value, with potential for further reduction. The case-study includes reaction steps typically used by the pharmaceutical

  17. Active pharmaceutical ingredient (API) production involving continuous processes – A process system engineering (PSE)-assisted design framework

    DEFF Research Database (Denmark)

    Cervera Padrell, Albert Emili; Skovby, Tommy; Kiil, Søren

    2012-01-01

    and fermentation-based products. The method exploits the synergic combination of continuous flow technologies (e.g., microfluidic techniques) and process systems engineering (PSE) methods and tools for faster process design and increased process understanding throughout the whole drug product and process...... kg of product – was reduced to half of its initial value, with potential for further reduction. The case-study includes reaction steps typically used by the pharmaceutical industry featuring different characteristic reaction times, as well as L–L separation and distillation-based solvent exchange...

  18. Nonlinear laser-plasma interactions

    Science.gov (United States)

    Kaw, P. K.

    2017-12-01

    Soon after lasers were invented, there was tremendous curiosity on the nonlinear phenomena which would result in their interaction with a fully ionized plasma. Apart from the basic interest, it was realized that it could be used for the achievement of nuclear fusion in the laboratory. This led us to a paper on the propagation of a laser beam into an inhomogeneous fusion plasma, where it was first demonstrated that light would go up to the critical layer (where the frequency matches the plasma frequency) and get reflected from there with a reflection coefficient of order unity. The reflection coefficient was determined by collisional effects. Since the wave was expected to slow down to near zero group speed at the reflection point, the dominant collision frequency determining the reflection coefficient was the collision frequency at the reflection point. It turned out that the absorption of light was rather small for fusion temperatures. This placed a premium on investigation of nonlinear phenomena which might contribute to the absorption and penetration of the light into high-density plasma. An early investigation showed that electron jitter with respect to ions would be responsible for the excitation of decay instabilities which convert light waves into electrostatic plasma waves and ion waves near the critical frequency. These electrostatic waves would then get absorbed into the plasma even in the collisionless case and lead to plasma heating which is nonlinear. Detailed estimates of this heating were made. Similar nonlinear processes which could lead to stimulated scattering of light in the underdense region (ω >ω _p) were investigated together with a number of other workers. All these nonlinear processes need a critical threshold power for excitation. Another important process which was discovered around the same time had to do with filamentation and trapping of light when certain thresholds were exceeded. All of this work has been extensively verified in

  19. Power relations and contrasting conceptions of evidence in patient-involvement processes used to inform health funding decisions in Australia.

    Science.gov (United States)

    Lopes, Edilene; Carter, Drew; Street, Jackie

    2015-06-01

    We collected and analysed views of key stakeholders on the processes used to involve patient organisations in health care funding decision making in Australia. We conducted 12 semi-structured interviews with patient organisation representatives and members of Advisory Committees that provide advice to the Australian Department of Health and employ Health Technology Assessment (HTA) as an evaluation framework. Using two theoretical frameworks, we analysed structural and contextual elements pertaining to the involvement processes. The findings reported in this article relate to interviewees' perspectives on contextual elements, analysed using a Foucauldian lens. These elements include: the perspectives of marginalised voices; the diversity of views on what ought to be considered valid evidence in a HTA setting; and the relationships between stakeholders, along with how these relationships impact on involvement processes and the outcomes of those processes. The findings demonstrate that the involvement processes currently used are deemed inadequate by both patient organisation representatives and Advisory Committee members, but for different reasons connected to how different stakeholders conceptualise evidence. Advisory Committee members viewed evidence as encompassing clinical outcomes and patient preferences, whereas patient organisation representatives tended to view evidence as encompassing aspects not directly related to a disease entity, such as the social and emotional aspects of patients' experiences in living with illness. Patient organisation representatives reported interacting with other stakeholders (especially industry) to increase the influence of their conception of evidence on decision making. The use of this strategy by interviewees illustrates how power struggles occur in government decision-making processes which involve both medical expertise and patients' accounts. Such struggles, and the power differentials they reflect, need to be considered

  20. Nonlinear Elasticity

    Science.gov (United States)

    Fu, Y. B.; Ogden, R. W.

    2001-05-01

    This collection of papers by leading researchers in the field of finite, nonlinear elasticity concerns itself with the behavior of objects that deform when external forces or temperature gradients are applied. This process is extremely important in many industrial settings, such as aerospace and rubber industries. This book covers the various aspects of the subject comprehensively with careful explanations of the basic theories and individual chapters each covering a different research direction. The authors discuss the use of symbolic manipulation software as well as computer algorithm issues. The emphasis is placed firmly on covering modern, recent developments, rather than the very theoretical approach often found. The book will be an excellent reference for both beginners and specialists in engineering, applied mathematics and physics.

  1. The impact of stakeholder involvement in hospital policy decision-making: a study of the hospital's business processes.

    Science.gov (United States)

    Malfait, Simon; Van Hecke, Ann; Hellings, Johan; De Bodt, Griet; Eeckloo, Kristof

    2017-02-01

    In many health care systems, strategies are currently deployed to engage patients and other stakeholders in decisions affecting hospital services. In this paper, a model for stakeholder involvement is presented and evaluated in three Flemish hospitals. In the model, a stakeholder committee advises the hospital's board of directors on themes of strategic importance. To study the internal hospital's decision processes in order to identify the impact of a stakeholder involvement committee on strategic themes in the hospital decision processes. A retrospective analysis of the decision processes was conducted in three hospitals that implemented a stakeholder committee. The analysis consisted of process and outcome evaluation. Fifteen themes were discussed in the stakeholder committees, whereof 11 resulted in a considerable change. None of these were on a strategic level. The theoretical model was not applied as initially developed, but was altered by each hospital. Consequentially, the decision processes differed between the hospitals. Despite alternation of the model, the stakeholder committee showed a meaningful impact in all hospitals on the operational level. As a result of the differences in decision processes, three factors could be identified as facilitators for success: (1) a close interaction with the board of executives, (2) the inclusion of themes with a more practical and patient-oriented nature, and (3) the elaboration of decisions on lower echelons of the organization. To effectively influence the organization's public accountability, hospitals should involve stakeholders in the decision-making process of the organization. The model of a stakeholder committee was not applied as initially developed and did not affect the strategic decision-making processes in the involved hospitals. Results show only impact at the operational level in the participating hospitals. More research is needed connecting stakeholder involvement with hospital governance.

  2. Involvement of External Stakeholders in Local Health Policymaking Process: A Case Study from Odense Municipality, Denmark

    Science.gov (United States)

    Karlsson, Leena Eklund; Jakobsen, Mette Winge; Winblad, Malin; Aro, Arja R.

    2017-01-01

    Collaboration between research and policy is an essential element for knowledge-based public health. However, only half of the Danish municipalities have experience with collaborating with researchers or other stakeholders. Through content analysis of interviews and policy documents the study explores the involvement of external stakeholders in…

  3. Software Quality Perceptions of Stakeholders Involved in the Software Development Process

    Science.gov (United States)

    Padmanabhan, Priya

    2013-01-01

    Software quality is one of the primary determinants of project management success. Stakeholders involved in software development widely agree that quality is important (Barney and Wohlin 2009). However, they may differ on what constitutes software quality, and which of its attributes are more important than others. Although, software quality…

  4. Biological and geochemical processes involved during denitrification in Callovo-Oxfordian clay

    International Nuclear Information System (INIS)

    Ollivier, P.; Parmentier, M.; Joulian, C.; Pauwels, H.; Albrecht, A.

    2012-01-01

    geochemical and biological variations observed in the experiments, biogeochemical modeling is carried out using the geochemical software PHREEQC. The present work builds upon two previous studies done at BRGM: the formulation of a COx pore water model and the creation of a kinetic biological denitrification model the latter. Because of the large uncertainties on the estimation of biomass based on the classic optical microscopy method, the quantification of NarG gene is used for biogeochemical modeling. To account for the observed presence of two nitrate reduction products, two sets of kinetic parameters are used to correctly represent experimental data: one in the early stage of experiments and another for the rest of experiments. Bacterial growth is modeled using acetate and nitrate as carbon and nitrogen sources. Calculated bacterial concentrations are in good agreement with NarG gene data. The calculated mass-balance indicates that about 40% of the carbon from acetate is used for anabolism and 60% for catabolism. Although, some discrepancies are still present between modeled and experimental pH evolution, the model is able to reproduce important changes such as the decrease of dissolved calcium in experiment with COx. This drop in Ca is explained by calcite precipitation and to a lesser extent by cation exchange. Experiments are still ongoing. It appears that nitrate is still decreasing. Further work should be done. In this study, we use acetate but other electron donors such as H 2 need to be investigated. Also, the synthetic solution representative of COx pore water is amended with Pseudomonas mandelii. Other bacteria should be considered. Finally, it would be interesting to work on the quantification of bacterial messenger RNA. Our preliminary tests show that this approach may provide more precise information on the biomass fraction actively involved in denitrification process. The next step could be to work with a consortium of bacteria

  5. Mitochondrial correlates of signaling processes involved with the cellular response to eimeria infection in broiler chickens

    Science.gov (United States)

    Host cellular responses to coccidiosis infection are consistent with elements of apoptosis, autophagy, and necrosis. These processes are enhanced in the cell through cell-directed signaling or repressed through parasite-derived inhibitors of these processes favoring the survival of the parasite. Acr...

  6. Interplay of break-up and transfer processes in reactions involving weakly-bound systems

    Science.gov (United States)

    Vitturi, Andrea; Moschini, Laura

    2018-02-01

    In this note we illustrate some applications of a simple model which has been devised to clarify the reaction mechanism and the interplay of different reaction channels (elastic, inelastic, transfer, break-up) in heavy-ion collisions. The model involves two potential wells moving in one dimension and few active particles; in spite of its simplicity, it is supposed to maintain the main features, the properties and the physics of the full three-dimensional case. Special attention is given to the role of continuum states in reactions involving weakly-bound systems, and different approximation schemes (as first-order or coupled-channels) as well as different continuum discretization procedures are tested. In the case of two active particles the reaction mechanism associated with two-particle transfer and the effect of pairing intearction are investigated. Work done in collaboration with Antonio Moro and Kouichi Hagino

  7. Streptomyces lunalinharesii Strain 235 Shows the Potential to Inhibit Bacteria Involved in Biocorrosion Processes

    OpenAIRE

    Pacheco da Rosa, Juliana; Korenblum, Elisa; Franco-Cirigliano, Marcella Novaes; Abreu, Fernanda; Lins, Ulysses; Soares, Rosângela M. A.; Macrae, Andrew; Seldin, Lucy; Coelho, Rosalie R. R.

    2013-01-01

    Four actinomycete strains previously isolated from Brazilian soils were tested for their antimicrobial activity against Bacillus pumilus LF-4 and Desulfovibrio alaskensis NCIMB 13491, bacteria that are well known to be involved in biofilm formation and biocorrosion. Strain 235, belonging to the species Streptomyces lunalinharesii, inhibited the growth of both bacteria. The antimicrobial activity was seen over a wide range of pH, and after treatment with several chemicals and heat but not with...

  8. Nonlinear Optics and Applications

    Science.gov (United States)

    Abdeldayem, Hossin A. (Editor); Frazier, Donald O. (Editor)

    2007-01-01

    Nonlinear optics is the result of laser beam interaction with materials and started with the advent of lasers in the early 1960s. The field is growing daily and plays a major role in emerging photonic technology. Nonlinear optics play a major role in many of the optical applications such as optical signal processing, optical computers, ultrafast switches, ultra-short pulsed lasers, sensors, laser amplifiers, and many others. This special review volume on Nonlinear Optics and Applications is intended for those who want to be aware of the most recent technology. This book presents a survey of the recent advances of nonlinear optical applications. Emphasis will be on novel devices and materials, switching technology, optical computing, and important experimental results. Recent developments in topics which are of historical interest to researchers, and in the same time of potential use in the fields of all-optical communication and computing technologies, are also included. Additionally, a few new related topics which might provoke discussion are presented. The book includes chapters on nonlinear optics and applications; the nonlinear Schrodinger and associated equations that model spatio-temporal propagation; the supercontinuum light source; wideband ultrashort pulse fiber laser sources; lattice fabrication as well as their linear and nonlinear light guiding properties; the second-order EO effect (Pockels), the third-order (Kerr) and thermo-optical effects in optical waveguides and their applications in optical communication; and, the effect of magnetic field and its role in nonlinear optics, among other chapters.

  9. Strategic Co-Location in a Hybrid Process Involving Desalination and Pressure Retarded Osmosis (PRO)

    Science.gov (United States)

    Sim, Victor S.T.; She, Qianhong; Chong, Tzyy Haur; Tang, Chuyang Y.; Fane, Anthony G.; Krantz, William B.

    2013-01-01

    This paper focuses on a Hybrid Process that uses feed salinity dilution and osmotic power recovery from Pressure Retarded Osmosis (PRO) to achieve higher overall water recovery. This reduces the energy consumption and capital costs of conventional seawater desalination and water reuse processes. The Hybrid Process increases the amount of water recovered from the current 66.7% for conventional seawater desalination and water reuse processes to a potential 80% through the use of reclaimed water brine as an impaired water source. A reduction of up to 23% in energy consumption is projected via the Hybrid Process. The attractiveness is amplified by potential capital cost savings ranging from 8.7%–20% compared to conventional designs of seawater desalination plants. A decision matrix in the form of a customizable scorecard is introduced for evaluating a Hybrid Process based on the importance of land space, capital costs, energy consumption and membrane fouling. This study provides a new perspective, looking at processes not as individual systems but as a whole utilizing strategic co-location to unlock the synergies available in the water-energy nexus for more sustainable desalination. PMID:24956940

  10. Strategic Co-Location in a Hybrid Process Involving Desalination and Pressure Retarded Osmosis (PRO

    Directory of Open Access Journals (Sweden)

    William B. Krantz

    2013-07-01

    Full Text Available This paper focuses on a Hybrid Process that uses feed salinity dilution and osmotic power recovery from Pressure Retarded Osmosis (PRO to achieve higher overall water recovery. This reduces the energy consumption and capital costs of conventional seawater desalination and water reuse processes. The Hybrid Process increases the amount of water recovered from the current 66.7% for conventional seawater desalination and water reuse processes to a potential 80% through the use of reclaimed water brine as an impaired water source. A reduction of up to 23% in energy consumption is projected via the Hybrid Process. The attractiveness is amplified by potential capital cost savings ranging from 8.7%–20% compared to conventional designs of seawater desalination plants. A decision matrix in the form of a customizable scorecard is introduced for evaluating a Hybrid Process based on the importance of land space, capital costs, energy consumption and membrane fouling. This study provides a new perspective, looking at processes not as individual systems but as a whole utilizing strategic co-location to unlock the synergies available in the water-energy nexus for more sustainable desalination.

  11. An Experimental Study of Force Involved in Manual Rebar Bending Process

    Science.gov (United States)

    Deepu, Sasi; Vishnu, Rajendran S.; Harish, Mohan T.; Bhavani, Rao R.

    2018-02-01

    The work presents an experimental method of understanding the force applied during a manual rebar bending process. The study tracks the force with the variation of the angle of bend and the elapsed time from the start to the end of a complete manual rebar bending process. A sample of expert rebar bending labourers are used for conducting the experiment and the data processed to set a performance standard. If a simulator based rebar bending training can be provided for a novice, this standard can be used as a matrix to define how close a novice rebar bender is closing to the expertise.

  12. Child involvement, alliance, and therapist flexibility: process variables in cognitive-behavioural therapy for anxiety disorders in childhood.

    Science.gov (United States)

    Hudson, Jennifer L; Kendall, Philip C; Chu, Brian C; Gosch, Elizabeth; Martin, Erin; Taylor, Alan; Knight, Ashleigh

    2014-01-01

    This study examined the relations between treatment process variables and child anxiety outcomes. Independent raters watched/listened to taped therapy sessions of 151 anxiety-disordered (6-14 yr-old; M = 10.71) children (43% boys) and assessed process variables (child alliance, therapist alliance, child involvement, therapist flexibility and therapist functionality) within a manual-based cognitive-behavioural treatment. Latent growth modelling examined three latent variables (intercept, slope, and quadratic) for each process variable. Child age, gender, family income and ethnicity were examined as potential antecedents. Outcome was analyzed using factorially derived clinician, mother, father, child and teacher scores from questionnaire and structured diagnostic interviews at pretreatment, posttreatment and 12-month follow-up. Latent growth models demonstrated a concave quadratic curve for child involvement and therapist flexibility over time. A predominantly linear, downward slope was observed for alliance, and functional flexibility remained consistent over time. Increased alliance, child involvement and therapist flexibility showed some albeit inconsistent, associations with positive treatment outcome. Findings support the notion that maintaining the initial high level of alliance or involvement is important for clinical improvement. There is some support that progressively increasing alliance/involvement also positively impacts on treatment outcome. These findings were not consistent across outcome measurement points or reporters. Copyright © 2013 Elsevier Ltd. All rights reserved.

  13. Access to the decision-making process: opportunities for public involvement in the facility decommissioning process of the United States Nuclear Regulatory Commission

    International Nuclear Information System (INIS)

    Cameron, F.X.

    1996-01-01

    This paper discusses recent initiatives taken by the United States Nuclear Regulatory Commission NRC) to effectively involve the public in decommissioning decisions. Initiatives discussed include the Commission's rulemaking to establish the radiological criteria for decommissioning, as well as public involvement methods that have been used on a site-by-site basis. As un example of public involvement, the NRC is currently in the process of developing generic rules on the radiological criteria for the decontamination and decommissioning of NRC-licensed sites. Not only was this proposed rule developed through an extensive and novel approach for public involvement, but it also establishes the basic provisions that will govern public involvement in future NRC decisions on the decommissioning of individual sites. The aim is to provide the public with timely information about all phases of the NRC staff to express concerns and make recommendations. Th NRC recognizes the value and the necessity of effective public involvement in its regulatory activities and has initiated a number of changes to its regulatory program to accomplish this. From the NRC's perspective, it is much easier and less costly to incorporate these mechanisms for public involvement into the regulatory program early in the process, rather than try to add them after considerable public controversy on an action has already been generated. The historical antecedents for initiatives mentioned, as well as 'lessons learned' from prior experience are also discussed. (author)

  14. Nonlinear Science

    CERN Document Server

    Yoshida, Zensho

    2010-01-01

    This book gives a general, basic understanding of the mathematical structure "nonlinearity" that lies in the depths of complex systems. Analyzing the heterogeneity that the prefix "non" represents with respect to notions such as the linear space, integrability and scale hierarchy, "nonlinear science" is explained as a challenge of deconstruction of the modern sciences. This book is not a technical guide to teach mathematical tools of nonlinear analysis, nor a zoology of so-called nonlinear phenomena. By critically analyzing the structure of linear theories, and cl

  15. Nonlinear oscillations

    CERN Document Server

    Nayfeh, Ali Hasan

    1995-01-01

    Nonlinear Oscillations is a self-contained and thorough treatment of the vigorous research that has occurred in nonlinear mechanics since 1970. The book begins with fundamental concepts and techniques of analysis and progresses through recent developments and provides an overview that abstracts and introduces main nonlinear phenomena. It treats systems having a single degree of freedom, introducing basic concepts and analytical methods, and extends concepts and methods to systems having degrees of freedom. Most of this material cannot be found in any other text. Nonlinear Oscillations uses sim

  16. Thermal-hydraulic processes involved in loss of residual heat removal during reduced inventory operation

    International Nuclear Information System (INIS)

    Fletcher, C.D.; McHugh, P.R.; Naff, S.A.; Johnsen, G.W.

    1991-02-01

    This paper identifies the topics needed to understand pressurized water reactor response to an extended loss of residual heat removal event during refueling and maintenance outages. By identifying the possible plant conditions and cooling methods that would be used for each cooling mode, the controlling thermal-hydraulic processes and phenomena were identified. Controlling processes and phenomena include: gravity drain, core water boil-off, and reflux cooling processes. Important subcategories of the reflux cooling processes include: the initiation of reflux cooling from various plant conditions, the effects of air on reflux cooling, core level depression effects, issues regarding the steam generator secondaries, and the special case of boiler-condenser cooling with once-through steam generators. 25 refs., 6 figs., 1 tab

  17. All-Optical Control of Linear and Nonlinear Energy Transfer via the Zeno Effect

    Science.gov (United States)

    Guo, Xiang; Zou, Chang-Ling; Jiang, Liang; Tang, Hong X.

    2018-05-01

    Microresonator-based nonlinear processes are fundamental to applications including microcomb generation, parametric frequency conversion, and harmonics generation. While nonlinear processes involving either second- (χ(2 )) or third- (χ(3 )) order nonlinearity have been extensively studied, the interaction between these two basic nonlinear processes has seldom been reported. In this paper we demonstrate a coherent interplay between second- and third- order nonlinear processes. The parametric (χ(2 ) ) coupling to a lossy ancillary mode shortens the lifetime of the target photonic mode and suppresses its density of states, preventing the photon emissions into the target photonic mode via the Zeno effect. Such an effect is then used to control the stimulated four-wave mixing process and realize a suppression ratio of 34.5.

  18. ["Scholar officials": thoughts on the involvement of professional nurses in the political process].

    Science.gov (United States)

    Wang, Hsiu-Hung

    2014-08-01

    A growing number of nurses are concerned with / participate in public affairs, politics, and policymaking processes. In particular, nursing leaders are actively leveraging their collective power to create interdisciplinary alliances aimed at encouraging the media and government to confront key nursing issues and implement healthcare reform. This article highlights the political participation and policy-making process to address the meaning and essence of politics, politics and nursing, training and strategies of public affairs and political participation, the shift from academia to health policy, and facilitation of important health policies. It is hoped that nurses may appropriately use their status and influence to actively participate in political campaigns and the policymaking process. By using their professional knowledge and skills, nurses may not only protect patient safety and public health but also facilitate nursing professional development and promote the professional image of nursing.

  19. Analysis of Hazards Associated with a Process Involving Uranium Metal and Uranium Hydride Powders

    Energy Technology Data Exchange (ETDEWEB)

    Bullock, J.S.

    2000-05-01

    An analysis of the reaction chemistry and operational factors associated with processing uranium and uranium hydride powders is presented, focusing on a specific operation in the Development Division which was subjected to the Job Hazard Analysis (JHA) process. Primary emphasis is on the thermodynamic factors leading to pyrophoricity in common atmospheres. The discussion covers feed powders, cold-pressed and hot-pressed materials, and stray material resulting from the operations. The sensitivity of the various forms of material to pyrophoricity in common atmospheres is discussed. Operational recommendations for performing the work described are given.

  20. Neural Networks Involved in Adolescent Reward Processing: An Activation Likelihood Estimation Meta-Analysis of Functional Neuroimaging Studies

    Science.gov (United States)

    Silverman, Merav H.; Jedd, Kelly; Luciana, Monica

    2015-01-01

    Behavioral responses to, and the neural processing of, rewards change dramatically during adolescence and may contribute to observed increases in risk-taking during this developmental period. Functional MRI (fMRI) studies suggest differences between adolescents and adults in neural activation during reward processing, but findings are contradictory, and effects have been found in non-predicted directions. The current study uses an activation likelihood estimation (ALE) approach for quantitative meta-analysis of functional neuroimaging studies to: 1) confirm the network of brain regions involved in adolescents’ reward processing, 2) identify regions involved in specific stages (anticipation, outcome) and valence (positive, negative) of reward processing, and 3) identify differences in activation likelihood between adolescent and adult reward-related brain activation. Results reveal a subcortical network of brain regions involved in adolescent reward processing similar to that found in adults with major hubs including the ventral and dorsal striatum, insula, and posterior cingulate cortex (PCC). Contrast analyses find that adolescents exhibit greater likelihood of activation in the insula while processing anticipation relative to outcome and greater likelihood of activation in the putamen and amygdala during outcome relative to anticipation. While processing positive compared to negative valence, adolescents show increased likelihood for activation in the posterior cingulate cortex (PCC) and ventral striatum. Contrasting adolescent reward processing with the existing ALE of adult reward processing (Liu et al., 2011) reveals increased likelihood for activation in limbic, frontolimbic, and striatal regions in adolescents compared with adults. Unlike adolescents, adults also activate executive control regions of the frontal and parietal lobes. These findings support hypothesized elevations in motivated activity during adolescence. PMID:26254587

  1. Nonlinear estimation and control of automotive drivetrains

    CERN Document Server

    Chen, Hong

    2014-01-01

    Nonlinear Estimation and Control of Automotive Drivetrains discusses the control problems involved in automotive drivetrains, particularly in hydraulic Automatic Transmission (AT), Dual Clutch Transmission (DCT) and Automated Manual Transmission (AMT). Challenging estimation and control problems, such as driveline torque estimation and gear shift control, are addressed by applying the latest nonlinear control theories, including constructive nonlinear control (Backstepping, Input-to-State Stable) and Model Predictive Control (MPC). The estimation and control performance is improved while the calibration effort is reduced significantly. The book presents many detailed examples of design processes and thus enables the readers to understand how to successfully combine purely theoretical methodologies with actual applications in vehicles. The book is intended for researchers, PhD students, control engineers and automotive engineers. Hong Chen is a professor at the State Key Laboratory of Automotive Simulation and...

  2. A novel method combining cellular neural networks and the coupled nonlinear oscillators' paradigm involving a related bifurcation analysis for robust image contrast enhancement in dynamically changing difficult visual environments

    International Nuclear Information System (INIS)

    Chedjou, Jean Chamberlain; Kyamakya, Kyandoghere

    2010-01-01

    It is well known that a machine vision-based analysis of a dynamic scene, for example in the context of advanced driver assistance systems (ADAS), does require real-time processing capabilities. Therefore, the system used must be capable of performing both robust and ultrafast analyses. Machine vision in ADAS must fulfil the above requirements when dealing with a dynamically changing visual context (i.e. driving in darkness or in a foggy environment, etc). Among the various challenges related to the analysis of a dynamic scene, this paper focuses on contrast enhancement, which is a well-known basic operation to improve the visual quality of an image (dynamic or static) suffering from poor illumination. The key objective is to develop a systematic and fundamental concept for image contrast enhancement that should be robust despite a dynamic environment and that should fulfil the real-time constraints by ensuring an ultrafast analysis. It is demonstrated that the new approach developed in this paper is capable of fulfilling the expected requirements. The proposed approach combines the good features of the 'coupled oscillators'-based signal processing paradigm with the good features of the 'cellular neural network (CNN)'-based one. The first paradigm in this combination is the 'master system' and consists of a set of coupled nonlinear ordinary differential equations (ODEs) that are (a) the so-called 'van der Pol oscillator' and (b) the so-called 'Duffing oscillator'. It is then implemented or realized on top of a 'slave system' platform consisting of a CNN-processors platform. An offline bifurcation analysis is used to find out, a priori, the windows of parameter settings in which the coupled oscillator system exhibits the best and most appropriate behaviours of interest for an optimal resulting image processing quality. In the frame of the extensive bifurcation analysis carried out, analytical formulae have been derived, which are capable of determining the various

  3. Stress Leads to Aberrant Hippocampal Involvement When Processing Schema-Related Information

    Science.gov (United States)

    Vogel, Susanne; Kluen, Lisa Marieke; Fernández, Guillén; Schwabe, Lars

    2018-01-01

    Prior knowledge, represented as a mental schema, has critical impact on how we organize, interpret, and process incoming information. Recent findings indicate that the use of an existing schema is coordinated by the medial prefrontal cortex (mPFC), communicating with parietal areas. The hippocampus, however, is crucial for encoding…

  4. Involvement of O-glycosylation defining oncofetal fibronectin in epithelial-mesenchymal transition process

    DEFF Research Database (Denmark)

    Freire-de-Lima, Leonardo; Gelfenbeyn, Kirill; Ding, Yao

    2011-01-01

    The process termed "epithelial-mesenchymal transition" (EMT) was originally discovered in ontogenic development, and has been shown to be one of the key steps in tumor cell progression and metastasis. Recently, we showed that the expression of some glycosphingolipids (GSLs) is down-regulated during...

  5. Data, analysis and modeling of physical properties for process designof systems involving lipids

    DEFF Research Database (Denmark)

    Cunico, Larissa; Ceriani, Roberta; Sarup, Bent

    2013-01-01

    Pure component and mixture properties are necessary for synthesis, design, and analysis of processes forthe production of edible oils, fats, biodiesel, and other lipids. The lack of measured data for these systemsmakes it necessary to develop reliable predictive models based on limited data. We...

  6. GWAS for executive function and processing speed suggests involvement of the CADM2 gene

    NARCIS (Netherlands)

    C.A. Ibrahim-Verbaas (Carla); J. Bressler; S. Debette (Stéphanie); M. Schuur (Maaike); A.V. Smith; J.C. Bis (Joshua); G. Davies (Gail); S. Trompet (Stella); J.A. Smith; A. Björnsson (Asgeir); L.B. Chibnik (Lori); Y. Liu; V. Vitart (Veronique); M. Kirin (Mirna); K. Petrovic (Katja); O. Polasek (Ozren); L. Zgaga (Lina); C. Fawns-Ritchie; P. Hoffmann (Per); J. Karjalainen (Juha); J. Lahti; D.J. Llewellyn; C.O. Schmidt (Carsten O.); R. Mather; V. Chouraki (Vincent); Q. Sun; S. Resnick (Susan); L.M. Rose (Lynda M.); C. Oldmeadow (Christopher); M. Stewart; B.H. Smith; V. Gudnason (Vilmundur); Q. Yang (Qiong); S.S. Mirza (Saira); J.W. Jukema; P.L. DeJager (Philip L.); T.B. Harris (Tamara); D.C. Liewald (David C.); N. Amin (Najaf); L.H. Coker (Laura); O. Stegle (Oliver); O.L. Lopez; R. Schmidt; A. Teumer (Alexander); I. Ford; N. Karbalai (Nazanin); J.T. Becker (James); M.K. Jonsdottir (Maria K.); R. Au; R.S.N. Fehrmann (Rudolf); S. Herms (Stefan); M.A. Nalls (Michael); W. Zhao; S.T. Turner; K. Yaffe; K. Lohman (Kurt); J.C. van Swieten (John); S.L.R. Kardia; D.S. Knopman (David); W.M. Meeks (William); G. Heiss (Gerardo); E.G. Holliday (Elizabeth); P.W. Schofield; T. Tanaka (Toshiko); D.J. Stott (David J.); J. Wang (Jing); P.M. Ridker (Paul); A.J. Gow; A. Pattie (Alison); J.M. Starr (John); L.J. Hocking; N.J. Armstrong (Nicola J.); S. McLachlan (Stela); L. Shulman (Lee); L.C. Pilling (Luke); G. Eiriksdottir (Gudny); R.J. Scott; N.A. Kochan (Nicole A.); A. Palotie; Y.-C. Hsieh; J.G. Eriksson (Johan G.); A.D. Penman (Alan); R.F. Gottesman (Rebecca); B.A. Oostra (Ben); L. Yu; A.L. DeStefano (Anita L.); A. Beiser; M. Garcia; J.I. Rotter; M.M. Nöthen; A. Hofman (Albert); P.E. Slagboom (Eline); R.G.J. Westendorp; B.M. Buckley (Brendan M.); P.A. Wolf; A.G. Uitterlinden (André); B.M. Psaty (Bruce); H.J. Grabe (Hans Jörgen); S. Bandinelli (Stefania); D.I. Chasman (Daniel); F. Grodstein (Francine); K. Räikkönen (Katri); J.-C. Lambert; D.J. Porteous (David J.); J.F. Price (Jackie F.); P.S. Sachdev (Perminder); L. Ferrucci (Luigi); J. Attia (John); I. Rudan (Igor); C. Hayward; A.F. Wright; J.F. Wilson (James F); S. Cichon (Sven); L. Franke (Lude); H. Schmidt; J. Ding (Jingzhong); A.J. de Craen (Anton); M. Fornage (Myriam); D.A. Bennett (David); I.J. Deary (Ian); M.A. Ikram (Arfan); L.J. Launer (Lenore); A.L. Fitzpatrick; S. Seshadri (Sudha); C.M. van Duijn (Cornelia); T.H. Mosley (Thomas H.)

    2016-01-01

    textabstractTo identify common variants contributing to normal variation in two specific domains of cognitive functioning, we conducted a genome-wide association study (GWAS) of executive functioning and information processing speed in non-demented older adults from the CHARGE (Cohorts for Heart and

  7. A Mathematical Experience Involving Defining Processes: In-Action Definitions and Zero-Definitions

    Science.gov (United States)

    Ouvrier-Buffet, Cecile

    2011-01-01

    In this paper, a focus is made on defining processes at stake in an unfamiliar situation coming from discrete mathematics which brings surprising mathematical results. The epistemological framework of Lakatos is questioned and used for the design and the analysis of the situation. The cognitive background of Vergnaud's approach enriches the study…

  8. An appraisal of the hydrogeological processes involved in shallow subsurface radioactive waste management in Canadian terrain

    International Nuclear Information System (INIS)

    Grisak, G.E.; Jackson, R.E.

    1978-01-01

    The hydrogeological aspects of the problem of low-level radioactive waste management are introduced with a discussion of the Canadian nuclear power program; the nature of radioactive wastes and their rates of production; and the half-lives and health effects of ''waste'' radionuclides. As well, a general account is given of the present Canadian policy and procedures for licensing radioactive waste management sites. Following this introductory material, a detailed account is presented of the geohydrologic processes controlling the transport of radionuclides in groundwater flow systems and the attendant geochemical processes causing the retardation of the radionuclides. These geohydrologic and geochemical processes (i.e., hydrogeological processes) can be evaluated by the measurement of certain variables such as aquifer dispersivity, groundwater velocity, hydraulic conductivity, cation-exchange capacity, and total competing cations. To assess the possible importance of each variable in Canadian terrain, a comprehensive discussion of presently available (Canadian) data that have been compiled pertaining to each variable is presented. A description is then given of the hydrogeology of and the waste management experiences at radioactive waste management sites at Chalk River, Ontario; Bruce, Ontario; Whiteshell, Manitoba; and Suffield, Alberta. Along with this description there is a brief evaluation of those geohydrologic and geochemical processes that may be of importance at these sites. As a consequence of the above, site criteria outlining the nature of desirable hydrogeological environments for radioactive waste management areas are presented for those situations where the groundwater flow system acts as (a) a barrier to the migration of escaped radioactivity and (b) a joint dispersion-retardation system for liquid wastes. (author)

  9. Coronin 3 involvement in F-actin-dependent processes at the cell cortex

    International Nuclear Information System (INIS)

    Rosentreter, Andre; Hofmann, Andreas; Xavier, Charles-Peter; Stumpf, Maria; Noegel, Angelika A.; Clemen, Christoph S.

    2007-01-01

    The actin interaction of coronin 3 has been mainly documented by in vitro experiments. Here, we discuss coronin 3 properties in the light of new structural information and focus on assays that reflect in vivo roles of coronin 3 and its impact on F-actin-associated functions. Using GFP-tagged coronin 3 fusion proteins and RNAi silencing we show that coronin 3 has roles in wound healing, protrusion formation, cell proliferation, cytokinesis, endocytosis, axonal growth, and secretion. During formation of cell protrusions actin accumulation precedes the focal enrichment of coronin 3 suggesting a role for coronin 3 in events that follow the initial F-actin assembly. Moreover, we show that coronin 3 similar to other coronins interacts with the Arp2/3-complex and cofilin indicating that this family in general is involved in regulating Arp2/3-mediated events

  10. Impact of schoolchildren's involvement in the design process on the effectiveness of healthy food promotion materials

    Directory of Open Access Journals (Sweden)

    Christopher R. Gustafson

    2017-06-01

    Relative to baseline, students in group 4 doubled their vegetable consumption (p < 0.001 when materials were posted. Vegetable consumption remained elevated at a follow-up 2–3 months later (p < 0.05. Students in group 3 initially increased the quantity of vegetables selected (p < 0.05, but did not increase consumption. In the follow-up period, however, students in group 3 increased their vegetable consumption (p < 0.01. Involving elementary-aged students in the design of vegetable promotional materials that were posted in the lunchroom increased the amount of vegetables students consumed.

  11. Silicon Regulates Potential Genes Involved in Major Physiological Processes in Plants to Combat Stress

    Directory of Open Access Journals (Sweden)

    Abinaya Manivannan

    2017-08-01

    Full Text Available Silicon (Si, the quasi-essential element occurs as the second most abundant element in the earth's crust. Biological importance of Si in plant kingdom has become inevitable particularly under stressed environment. In general, plants are classified as high, medium, and low silicon accumulators based on the ability of roots to absorb Si. The uptake of Si directly influence the positive effects attributed to the plant but Si supplementation proves to mitigate stress and recover plant growth even in low accumulating plants like tomato. The application of Si in soil as well as soil-less cultivation systems have resulted in the enhancement of quantitative and qualitative traits of plants even under stressed environment. Silicon possesses several mechanisms to regulate the physiological, biochemical, and antioxidant metabolism in plants to combat abiotic and biotic stresses. Nevertheless, very few reports are available on the aspect of Si-mediated molecular regulation of genes with potential role in stress tolerance. The recent advancements in the era of genomics and transcriptomics have opened an avenue for the determination of molecular rationale associated with the Si amendment to the stress alleviation in plants. Therefore, the present endeavor has attempted to describe the recent discoveries related to the regulation of vital genes involved in photosynthesis, transcription regulation, defense, water transport, polyamine synthesis, and housekeeping genes during abiotic and biotic stress alleviation by Si. Furthermore, an overview of Si-mediated modulation of multiple genes involved in stress response pathways such as phenylpropanoid pathway, jasmonic acid pathway, ABA-dependent or independent regulatory pathway have been discussed in this review.

  12. Nonlinear systems

    CERN Document Server

    Palmero, Faustino; Lemos, M; Sánchez-Rey, Bernardo; Casado-Pascual, Jesús

    2018-01-01

    This book presents an overview of the most recent advances in nonlinear science. It provides a unified view of nonlinear properties in many different systems and highlights many  new developments. While volume 1 concentrates on mathematical theory and computational techniques and challenges, which are essential for the study of nonlinear science, this second volume deals with nonlinear excitations in several fields. These excitations can be localized and transport energy and matter in the form of breathers, solitons, kinks or quodons with very different characteristics, which are discussed in the book. They can also transport electric charge, in which case they are known as polarobreathers or solectrons. Nonlinear excitations can influence function and structure in biology, as for example, protein folding. In crystals and other condensed matter, they can modify transport properties, reaction kinetics and interact with defects. There are also engineering applications in electric lattices, Josephson junction a...

  13. The forced nonlinear Schroedinger equation

    International Nuclear Information System (INIS)

    Kaup, D.J.; Hansen, P.J.

    1985-01-01

    The nonlinear Schroedinger equation describes the behaviour of a radio frequency wave in the ionosphere near the reflexion point where nonlinear processes are important. A simple model of this phenomenon leads to the forced nonlinear Schroedinger equation in terms of a nonlinear boundary value problem. A WKB analysis of the time evolution equations for the nonlinear Schroedinger equation in the inverse scattering transform formalism gives a crude order of magnitude estimation of the qualitative behaviour of the solutions. This estimation is compared with the numerical solutions. (D.Gy.)

  14. Psychopathological Processes Involved in Social Comparison, Depression, and Envy on Facebook

    OpenAIRE

    Aurel Pera

    2018-01-01

    Is Facebook utilization beneficial or detrimental for psychological well-being? I draw on outstanding research (e.g., Chou and Edge, 2012; Lin and Utz, 2015; Appel et al., 2016; Ehrenreich and Underwood, 2016; Vogel and Rose, 2016; Hu et al., 2017) to substantiate that examining other individuals’ positively presented material on Facebook may have detrimental consequences. Increasing comparisons on Facebook may generate feelings of envy, the latter being a significant process determining the ...

  15. Increased functional connectivity with puberty in the mentalising network involved in social emotion processing

    Science.gov (United States)

    Klapwijk, Eduard T.; Goddings, Anne-Lise; Heyes, Stephanie Burnett; Bird, Geoffrey; Viner, Russell M.; Blakemore, Sarah-Jayne

    2015-01-01

    There is increasing evidence that puberty plays an important role in the structural and functional brain development seen in adolescence, but little is known of the pubertal influence on changes in functional connectivity. We explored how pubertal indicators (salivary concentrations of testosterone, oestradiol and DHEA; pubertal stage; menarcheal status) relate to functional connectivity between components of a mentalising network identified to be engaged in social emotion processing by our prior work, using psychophysiological interaction (PPI) analysis. Female adolescents aged 11 to 13 years were scanned whilst silently reading scenarios designed to evoke either social emotions (guilt and embarrassment) or basic emotions (disgust and fear), of which only social compared to basic emotions require the representation of another person’s mental states. Pubertal stage and menarcheal status were used to assign participants to pre/early or mid/late puberty groups. We found increased functional connectivity between the dorsomedial prefrontal cortex (DMPFC) and the right posterior superior temporal sulcus (pSTS) and right temporo-parietal junction (TPJ) during social relative to basic emotion processing. Moreover, increasing oestradiol concentrations were associated with increased functional connectivity between the DMPFC and the right TPJ during social relative to basic emotion processing, independent of age. Our analysis of the PPI data by phenotypic pubertal status showed that more advanced puberty stage was associated with enhanced functional connectivity between the DMPFC and the left anterior temporal cortex (ATC) during social relative to basic emotion processing, also independent of age. Our results suggest increased functional maturation of the social brain network with the advancement of puberty in girls. PMID:23998674

  16. Using dual-task methodology to dissociate automatic from nonautomatic processes involved in artificial grammar learning.

    Science.gov (United States)

    Hendricks, Michelle A; Conway, Christopher M; Kellogg, Ronald T

    2013-09-01

    Previous studies have suggested that both automatic and intentional processes contribute to the learning of grammar and fragment knowledge in artificial grammar learning (AGL) tasks. To explore the relative contribution of automatic and intentional processes to knowledge gained in AGL, we utilized dual-task methodology to dissociate automatic and intentional grammar- and fragment-based knowledge in AGL at both acquisition and at test. Both experiments used a balanced chunk strength grammar to assure an equal proportion of fragment cues (i.e., chunks) in grammatical and nongrammatical test items. In Experiment 1, participants engaged in a working memory dual-task either during acquisition, test, or both acquisition and test. The results showed that participants performing the dual-task during acquisition learned the artificial grammar as well as the single-task group, presumably by relying on automatic learning mechanisms. A working memory dual-task at test resulted in attenuated grammar performance, suggesting a role for intentional processes for the expression of grammatical learning at test. Experiment 2 explored the importance of perceptual cues by changing letters between the acquisition and test phase; unlike Experiment 1, there was no significant learning of grammatical information for participants under dual-task conditions in Experiment 2, suggesting that intentional processing is necessary for successful acquisition and expression of grammar-based knowledge under transfer conditions. In sum, it appears that some aspects of learning in AGL are indeed relatively automatic, although the expression of grammatical information and the learning of grammatical patterns when perceptual similarity is eliminated both appear to require explicit resources. PsycINFO Database Record (c) 2013 APA, all rights reserved.

  17. Correlations in photon-numbers and integrated intensities in parametric processes involving three optical fields

    Czech Academy of Sciences Publication Activity Database

    Peřina, Jan; Křepelka, Jaromír; Peřina ml., Jan; Bondani, M.; Allevi, A.; Andreoni, A.

    2009-01-01

    Roč. 53, č. 3 (2009), 373-382 ISSN 1434-6060 R&D Projects: GA AV ČR KAN301370701; GA MŠk(CZ) 1M06002 Institutional research plan: CEZ:AV0Z10100522 Keywords : parametric process * three-mode state * sub-Poisson statistics * conditional measurement Subject RIV: BH - Optics, Masers, Lasers Impact factor: 1.420, year: 2009

  18. Forest Soil Bacteria: Diversity, Involvement in Ecosystem Processes, and Response to Global Change

    Czech Academy of Sciences Publication Activity Database

    Lladó, Salvador; López-Mondéjar, Rubén; Baldrian, Petr

    2017-01-01

    Roč. 81, č. 2 (2017), s. 1-27, č. článku e00063. ISSN 1092-2172 R&D Projects: GA ČR(CZ) GP14-09040P; GA MŠk(CZ) LD15086 Institutional support: RVO:61388971 Keywords : bacteria * decomposition * ecosystem processes Subject RIV: EE - Microbiology, Virology OBOR OECD: Microbiology Impact factor: 14.533, year: 2016

  19. TEACHING PHYSICS: An experiment to demonstrate the principles and processes involved in medical Doppler ultrasound

    Science.gov (United States)

    Andrews, D. G. H.

    2000-09-01

    Doppler ultrasound is widely used in medicine for measuring blood velocity. This paper describes an experiment illustrating the principles of medical Doppler ultrasound. It is designed with A-level/undergraduate physics students in mind. Ultrasound is transmitted in air and reflected from a moving target. The return signal is processed using a series of modules, so that students can discover for themselves how each stage in the instrument works. They can also obtain a quantitative value of the speed of the target.

  20. Solitary lower lumbar osteochondroma (spinous process of L3 involvement): a case report.

    Science.gov (United States)

    Hassankhani, Ebrahim Ghayem

    2009-12-20

    Solitary osteochondromas, which are the most common benign bone tumors of long bones, are rarely found in the vertebral column. A 16-year-old female patient presented with a hard palpable mass at lower lumbar region like a congenital deformity. Plain radiography illustrated a well-defined solid mass arising from the posterior elements of the L3 and ruled out any congenital anomalies. A computed tomography scan further determined a mass that arose from the spinous process of L3. The tumor was excised en bloc through a posterior approach and histopathological examination verified the diagnosis of osteocondroma.Osteochondromas are rarely found in the spine, when present in the spine, however, have a predilection for cervical or upper thoracic region arising usually from lamina of vertebrae and are rare in lumbosacral region and very rare at spinous process of the vertebrae.We present a case of osteochondroma locates in lumbar region and spinous process of vertebrae with unusual presentation and was considered clinically as congenital lumbar kyphosis.

  1. Alveolar process fractures in the permanent dentition. Part 2. The risk of healing complications in teeth involved in an alveolar process fracture

    DEFF Research Database (Denmark)

    Lauridsen, Eva; Gerds, Thomas; Andreasen, Jens Ove

    2016-01-01

    AIM: To analyze the risk of pulp canal obliteration (PCO), pulp necrosis (PN), repair-related resorption (RRR), infection-related resorption (IRR), ankylosis-related resorption (ARR), marginal bone loss (MBL), and tooth loss (TL) for teeth involved in an alveolar process fracture and to identify ...

  2. Entropy and convexity for nonlinear partial differential equations.

    Science.gov (United States)

    Ball, John M; Chen, Gui-Qiang G

    2013-12-28

    Partial differential equations are ubiquitous in almost all applications of mathematics, where they provide a natural mathematical description of many phenomena involving change in physical, chemical, biological and social processes. The concept of entropy originated in thermodynamics and statistical physics during the nineteenth century to describe the heat exchanges that occur in the thermal processes in a thermodynamic system, while the original notion of convexity is for sets and functions in mathematics. Since then, entropy and convexity have become two of the most important concepts in mathematics. In particular, nonlinear methods via entropy and convexity have been playing an increasingly important role in the analysis of nonlinear partial differential equations in recent decades. This opening article of the Theme Issue is intended to provide an introduction to entropy, convexity and related nonlinear methods for the analysis of nonlinear partial differential equations. We also provide a brief discussion about the content and contributions of the papers that make up this Theme Issue.

  3. Fair processes and fair outcomes: involving local stakeholders in RWM decisions

    International Nuclear Information System (INIS)

    Vari, A.

    2004-01-01

    There is a general agreement on the requirements to be met by radioactive waste management strategies. One of the requirements is that both the outcomes of any decisions and the decision-making processes must be seen to be fair. However, there exist multiple legitimate views on fairness and there is no meta-theory that could help decide which of the competing views should be considered valid in a concrete case. Referring to the plurality of views on fairness, Linnerooth-Bayer (forthcoming) argues that the impasse in facility siting processes can be attributed to the failure to take adequate account of the diverse views held by the various stakeholders on fair processes and outcomes. Three fundamental ethical principles have been derived from three basic ethical theories: well-being which is the central concept of utilitarian ethics, justice which is a key notion in egalitarian ethics, and dignity which is central to deontology (Bay and Oughton, 2003). According to utilitarian ethics fairness means that public welfare is maximized even at the cost of stakeholders' individual rights. Costs and benefits can be legitimately distributed in any way; only their overall balance has to be enhanced. In contrary, egalitarian ethics aims for a fair distribution of benefits and costs among stakeholders, while deontology acknowledges universal values of actions, e.g. the respect for individual rights, apart from their consequences. According to the latter ethics, fairness means that stakeholders themselves have the opportunity to learn about the benefits and costs of various options, and having considered them, decide on their position to accept them. How do diverse views on fair decisions materialize in RWM debates? (author)

  4. Process evaluation of the health education resource Abre los Ojos for street-involved youth in Medellín

    Directory of Open Access Journals (Sweden)

    John L. Wylie

    2012-02-01

    Full Text Available Objective: Conduct a process evaluation of a health education resource (pamphlet¸ Abre los Ojos, designed for street-involved youth in Medellín. The primary foci of the evaluation were the process of developing the resource and youth’s subsequent perception of the resource. Methodology: Drawing upon both qualitative and quantitative data, a process evaluation was undertaken. Ninety four street-involved youth between the ages of 14–24 years completed surveys about the resource. These semi-structured interviews were key for the information about youth perception of the resource. In addition to individual interviews, prior to resource creation, a series of focus groups were integral for the development of the resource. Results: The process of consulting with the target population through the focus groups was effective in obtaining their ideas and feedback about what type of content they would like to see in a health education resource, and how they wanted that content presented. After distribution, participants described that Abre los Ojos contained information that was valuable and relevant to their experiences. While not a primary focus of this evaluation, the individual interviews were also able to provide some preliminary insight into whether Abre los Ojos was an effective means for participants to increase their knowledge of content included in the resource. Conclusion: The collaborative process of jointly developing the resource content in partnership with the youth proved very worthwhile. While our research team chose to include information about HIV, through focus group dialogue, the youth themselves determined the additional content themes (piercings, use of solvents, and description of life on the street. The resulting resource was well-received by members of the street-involved population who had not been involved in its design.

  5. Patients' preferences for involvement in the decision-making process for treating diabetic retinopathy.

    Science.gov (United States)

    Marahrens, Lydia; Kern, Raimar; Ziemssen, Tjalf; Fritsche, Andreas; Martus, Peter; Ziemssen, Focke; Roeck, Daniel

    2017-08-09

    To assess factors associated with the preferred role of the attending ophthalmologist in the decision-making processes before treating diabetic retinopathy (DR). Cross-sectional study of 810 adults attending secondary diabetes care centers (NCT02311504). Diabetes patients were classified using a validated questionnaire in an ophthalmologist-dominant decision-making (ODM), shared decision-making (SDM) and patient-dominant decision-making (PDM) style. Multivariate logistic regression was performed to determine factors associated with the decision-making process. A majority of 74.3% patients preferred SDM between ophthalmologist and patient, 17.4% patients wanted ODM, delegating the decision-making process to the ophthalmologist, 8.3% preferred the autonomous style of PDM. Patients wanting ODM were older (OR = 1.2 per decade, p = 0.013), had a lower level of education (OR = 1.4, p = 0.001) and had a higher frequency of consultations per year (OR = 1.3, p = 0.022). Patients with better basic knowledge in DR and memorizing their HbA 1 c level showed a higher propensity for SDM (OR = 1.1, p = 0.037). Patients wanting PDM had a significantly higher education (OR = 1.3, p = 0.036) and a greater desire for receiving information from self-help groups (OR = 1.3, p = 0.015). The first evaluation of the general patient wishes for the treatment of DR confirmed the concept of SDM, which was favored by three quarters. In particular, older patients with low educational attainment wanted to delegate the decision-making process to the ophthalmologist. Amelioration of ophthalmologic education in diabetic programs might take up patients' propensity for SDM. Regardless of the decision-making group, nearly all patients wanted the medical and scientific information to be transferred by and shared with the ophthalmologist. The study was registered on www.clinicaltrials.gov (identifier: NCT02311504) on December 4th 2014.

  6. Nonlinear photonic metasurfaces

    Science.gov (United States)

    Li, Guixin; Zhang, Shuang; Zentgraf, Thomas

    2017-03-01

    Compared with conventional optical elements, 2D photonic metasurfaces, consisting of arrays of antennas with subwavelength thickness (the 'meta-atoms'), enable the manipulation of light-matter interactions on more compact platforms. The use of metasurfaces with spatially varying arrangements of meta-atoms that have subwavelength lateral resolution allows control of the polarization, phase and amplitude of light. Many exotic phenomena have been successfully demonstrated in linear optics; however, to meet the growing demand for the integration of more functionalities into a single optoelectronic circuit, the tailorable nonlinear optical properties of metasurfaces will also need to be exploited. In this Review, we discuss the design of nonlinear photonic metasurfaces — in particular, the criteria for choosing the materials and symmetries of the meta-atoms — for the realization of nonlinear optical chirality, nonlinear geometric Berry phase and nonlinear wavefront engineering. Finally, we survey the application of nonlinear photonic metasurfaces in optical switching and modulation, and we conclude with an outlook on their use for terahertz nonlinear optics and quantum information processing.

  7. The leech nervous system: a valuable model to study the microglia involvement in regenerative processes.

    Science.gov (United States)

    Le Marrec-Croq, Françoise; Drago, Francesco; Vizioli, Jacopo; Sautière, Pierre-Eric; Lefebvre, Christophe

    2013-01-01

    Microglia are intrinsic components of the central nervous system (CNS). During pathologies in mammals, inflammatory processes implicate the resident microglia and the infiltration of blood cells including macrophages. Functions of microglia appear to be complex as they exhibit both neuroprotective and neurotoxic effects during neuropathological conditions in vivo and in vitro. The medicinal leech Hirudo medicinalis is a well-known model in neurobiology due to its ability to naturally repair its CNS following injury. Considering the low infiltration of blood cells in this process, the leech CNS is studied to specify the activation mechanisms of only resident microglial cells. The microglia recruitment is known to be essential for the usual sprouting of injured axons and does not require any other glial cells. The present review will describe the questions which are addressed to understand the nerve repair. They will discuss the implication of leech factors in the microglial accumulation, the identification of nerve cells producing these molecules, and the study of different microglial subsets. Those questions aim to better understand the mechanisms of microglial cell recruitment and their crosstalk with damaged neurons. The study of this dialog is necessary to elucidate the balance of the inflammation leading to the leech CNS repair.

  8. The Leech Nervous System: A Valuable Model to Study the Microglia Involvement in Regenerative Processes

    Directory of Open Access Journals (Sweden)

    Françoise Le Marrec-Croq

    2013-01-01

    Full Text Available Microglia are intrinsic components of the central nervous system (CNS. During pathologies in mammals, inflammatory processes implicate the resident microglia and the infiltration of blood cells including macrophages. Functions of microglia appear to be complex as they exhibit both neuroprotective and neurotoxic effects during neuropathological conditions in vivo and in vitro. The medicinal leech Hirudo medicinalis is a well-known model in neurobiology due to its ability to naturally repair its CNS following injury. Considering the low infiltration of blood cells in this process, the leech CNS is studied to specify the activation mechanisms of only resident microglial cells. The microglia recruitment is known to be essential for the usual sprouting of injured axons and does not require any other glial cells. The present review will describe the questions which are addressed to understand the nerve repair. They will discuss the implication of leech factors in the microglial accumulation, the identification of nerve cells producing these molecules, and the study of different microglial subsets. Those questions aim to better understand the mechanisms of microglial cell recruitment and their crosstalk with damaged neurons. The study of this dialog is necessary to elucidate the balance of the inflammation leading to the leech CNS repair.

  9. The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process

    International Nuclear Information System (INIS)

    Park, Jeehye; Lee, Gina; Chung, Jongkyeong

    2009-01-01

    The two Parkinson's disease (PD) genes, PTEN-induced kinase 1 (PINK1) and parkin, are linked in a common pathway which affects mitochondrial integrity and function. However, it is still not known what this pathway does in the mitochondria. Therefore, we investigated its physiological function in Drosophila. Because Drosophila PINK1 and parkin mutants show changes in mitochondrial morphology in both indirect flight muscles and dopaminergic neurons, we here investigated whether the PINK1-Parkin pathway genetically interacts with the regulators of mitochondrial fusion and fission such as Drp1, which promotes mitochondrial fission, and Opa1 or Marf, which induces mitochondrial fusion. Surprisingly, DrosophilaPINK1 and parkin mutant phenotypes were markedly suppressed by overexpression of Drp1 or downregulation of Opa1 or Marf, indicating that the PINK1-Parkin pathway regulates mitochondrial remodeling process in the direction of promoting mitochondrial fission. Therefore, we strongly suggest that mitochondrial fusion and fission process could be a prominent therapeutic target for the treatment of PD.

  10. Can the BestGrid Process Improve Stakeholder Involvement in Electricity Transmission Projects?

    Directory of Open Access Journals (Sweden)

    Nadejda Komendantova

    2015-08-01

    Full Text Available The European Union has set ambitious targets for deployment of renewable energy sources to reach goals of climate change mitigation and energy security policies. However, the current state of electricity transmission infrastructure is a major bottleneck for further scaling up of renewable energy in the EU. Several thousands of kilometers of new lines have to be constructed and upgraded to accommodate growing volumes of intermittent renewable electricity. In many countries, construction of electricity transmission projects has been delayed for several years due to concerns of local stakeholders. The innovative BESTGRID approach, reported here, brings together transmission system operators (TSOs and non-governmental organizations (NGOs to discuss and understand the nature of stakeholder concerns. This paper has three objectives: (1 to understand stakeholder concerns about the deployment of electricity transmission grids in four pilot projects according to five guiding principles: need, transparency, engagement, environment, and impacts on human health as well as benefits; (2 to understand how these principles can be addressed to provide a basis for better decision-making outcomes; and (3 to evaluate the BESTGRID process based on feedback received from stakeholders and the level of participation achieved according to the ladder of Arnstein. This paper goes beyond a discussion of “measures to mitigate opposition” to understand how dialogue between TSOs and the public—represented mainly by NGOs and policy-makers—might lead to a better decision-making process and more sustainable electricity transmission infrastructure deployment.

  11. Perceptual grouping does not affect multi-attribute decision making if no processing costs are involved.

    Science.gov (United States)

    Ettlin, Florence; Bröder, Arndt

    2015-05-01

    Adaptive strategy selection implies that a decision strategy is chosen based on its fit to the task and situation. However, other aspects, such as the way information is presented, can determine information search behavior; especially when the application of certain strategies over others is facilitated. But are such display effects on multi-attribute decisions also at work when the manipulation does not entail differential costs for different decision strategies? Three Mouselab experiments with hidden information and one eye tracking experiment with an open information board revealed that decision behavior is unaffected by purely perceptual manipulations of the display based on Gestalt principles; that is, based on manipulations that induce no noteworthy processing costs for different information search patterns. We discuss our results in the context of previous findings on display effects; specifically, how the combination of these findings and our results reveal the crucial role of differential processing costs for different strategies for the emergence of display effects. This finding describes a boundary condition of the commonly acknowledged influence of information displays and is in line with the ideas of adaptive strategy selection and cost-benefit tradeoffs. Copyright © 2015. Published by Elsevier B.V.

  12. The imaging and modelling of the physical processes involved in digestion and absorption.

    Science.gov (United States)

    Schulze, K S

    2015-02-01

    The mechanical activity of the gastro-intestinal tract serves to store, propel and digest food. Contractions disperse particles and transform solids and secretions into the two-phase slurry called chyme; movements of the intestine deliver nutrients to mucosal sites of absorption, and from the submucosa into the lymphatic and portal venous circulation. Colonic motor activity helps to extract fluid and electrolytes from chyme and to compound and compact luminal debris into faeces for elimination. We outline how dynamic imaging by ultrasound and magnetic resonance can demonstrate intestinal flow processes critical to digestion like mixing, dilution, swelling, dispersion and elution. Computational fluid mechanics enables a numerical rendition of the forces promoting digestion: pressure and flow fields, the shear stresses dispersing particles or the effectiveness of bolus mixing can be calculated. These technologies provide new insights into the mechanical processes that promote digestion and absorption. © 2014 This article is a U.S. Government work and is in the public domain in the USA.

  13. E-cadherin junction formation involves an active kinetic nucleation process

    Science.gov (United States)

    Biswas, Kabir H.; Hartman, Kevin L.; Yu, Cheng-han; Harrison, Oliver J.; Song, Hang; Smith, Adam W.; Huang, William Y. C.; Lin, Wan-Chen; Guo, Zhenhuan; Padmanabhan, Anup; Troyanovsky, Sergey M.; Dustin, Michael L.; Shapiro, Lawrence; Honig, Barry; Zaidel-Bar, Ronen; Groves, Jay T.

    2015-01-01

    Epithelial (E)-cadherin-mediated cell−cell junctions play important roles in the development and maintenance of tissue structure in multicellular organisms. E-cadherin adhesion is thus a key element of the cellular microenvironment that provides both mechanical and biochemical signaling inputs. Here, we report in vitro reconstitution of junction-like structures between native E-cadherin in living cells and the extracellular domain of E-cadherin (E-cad-ECD) in a supported membrane. Junction formation in this hybrid live cell-supported membrane configuration requires both active processes within the living cell and a supported membrane with low E-cad-ECD mobility. The hybrid junctions recruit α-catenin and exhibit remodeled cortical actin. Observations suggest that the initial stages of junction formation in this hybrid system depend on the trans but not the cis interactions between E-cadherin molecules, and proceed via a nucleation process in which protrusion and retraction of filopodia play a key role. PMID:26290581

  14. Mixed reverse micelles facilitated downstream processing of lipase involving water-oil-water liquid emulsion membrane.

    Science.gov (United States)

    Bhowal, Saibal; Priyanka, B S; Rastogi, Navin K

    2014-01-01

    Our earlier work for the first time demonstrated that liquid emulsion membrane (LEM) containing reverse micelles could be successfully used for the downstream processing of lipase from Aspergillus niger. In the present work, we have attempted to increase the extraction and purification fold of lipase by using mixed reverse micelles (MRM) consisting of cationic and nonionic surfactants in LEM. It was basically prepared by addition of the internal aqueous phase solution to the organic phase followed by the redispersion of the emulsion in the feed phase containing enzyme, which resulted in globules of water-oil-water (WOW) emulsion for the extraction of lipase. The optimum conditions for maximum lipase recovery (100%) and purification fold (17.0-fold) were CTAB concentration 0.075 M, Tween 80 concentration 0.012 M, at stirring speed of 500 rpm, contact time 15 min, internal aqueous phase pH 7, feed pH 9, KCl concentration 1 M, NaCl concentration 0.1 M, and ratio of membrane emulsion to feed volume 1:1. Incorporation of the nonionic surfactant (e.g., Tween 80) resulted in remarkable improvement in the purification fold (3.1-17.0) of the lipase. LEM containing a mixture of nonionic and cationic surfactants can be successfully used for the enhancement in the activity recovery and purification fold during downstream processing of enzymes/proteins. © 2014 American Institute of Chemical Engineers.

  15. Are podoplanin and ezrin involved in the invasion process of the ameloblastomas?

    Directory of Open Access Journals (Sweden)

    Y.F. Costa

    2015-02-01

    Full Text Available The association between podoplanin and ezrin in the process of odontogenic tumors invasion has been suggested, but was not studied yet. Our purpose was to investigate the relationship between podoplanin and ezrin expressions in the odontogenic epithelium of ameloblastomas. Forty-seven ameloblastomas were analyzed by immunohistochemistry using anti-podoplanin and anti-ezrin antibodies. The expressions of both proteins were evaluated using a score method and the comparison and association between these proteins were verified, respectively, by Wilcoxon Signed-Rank test and by Spearman’s rank correlation coefficient, using a statistical significance level of 0.05. The majority of tumors (87.2% exhibited strong membranous expression of podoplanin in the peripheral cells. Cytoplasmic expression of ezrin in the peripheral cells of ameloblastomas was stronger than its membranous expression. No statistically significant correlation was observed between podoplanin and ezrin. However, there was statistically significant difference between membranous podoplanin and membranous ezrin expressions, between cytoplasmic podoplanin and membranous ezrin expressions, and between cytoplasmic podoplanin and cytoplasmic ezrin expressions. There was no statistical difference between membranous podoplanin and cytoplasmic ezrin expressions. These results suggest a synergistic role of both proteins in the process of invasion of ameloblastomas.

  16. A Comparative Study of Applying Active-Set and Interior Point Methods in MPC for Controlling Nonlinear pH Process

    Directory of Open Access Journals (Sweden)

    Syam Syafiie

    2014-06-01

    Full Text Available A comparative study of Model Predictive Control (MPC using active-set method and interior point methods is proposed as a control technique for highly non-linear pH process. The process is a strong acid-strong base system. A strong acid of hydrochloric acid (HCl and a strong base of sodium hydroxide (NaOH with the presence of buffer solution sodium bicarbonate (NaHCO3 are used in a neutralization process flowing into reactor. The non-linear pH neutralization model governed in this process is presented by multi-linear models. Performance of both controllers is studied by evaluating its ability of set-point tracking and disturbance-rejection. Besides, the optimization time is compared between these two methods; both MPC shows the similar performance with no overshoot, offset, and oscillation. However, the conventional active-set method gives a shorter control action time for small scale optimization problem compared to MPC using IPM method for pH control.

  17. Impact of schoolchildren's involvement in the design process on the effectiveness of healthy food promotion materials.

    Science.gov (United States)

    Gustafson, Christopher R; Abbey, Bryce M; Heelan, Kate A

    2017-06-01

    Marketing techniques may improve children's vegetable consumption. However, student participation in the design of marketing materials may increase the material's salience, while also improving children's commitment and attitudes towards healthy eating. The impact of student-led design of vegetable promotional materials on choice and consumption was investigated using 1614 observations of students' vegetable choice and plate waste in four public elementary schools in Kearney, Nebraska. Data were collected on children's vegetable choice and consumption in four comparison groups: 1) control; 2) students designed materials only; 3) students were exposed to promotional materials only; and 4) students designed materials that were then posted in the lunchroom. Vegetable choice and consumption data were collected through a validated digital photography-based plate-waste method. Multivariate linear regression was used to estimate average treatment effects of the conditions at various time periods. Dependent variables were vegetable choice and consumption, and independent variables included the condition, time period, and interaction terms, as well as controls for gender and grade. Relative to baseline, students in group 4 doubled their vegetable consumption ( p  < 0.001) when materials were posted. Vegetable consumption remained elevated at a follow-up 2-3 months later ( p  < 0.05). Students in group 3 initially increased the quantity of vegetables selected ( p  < 0.05), but did not increase consumption. In the follow-up period, however, students in group 3 increased their vegetable consumption ( p  < 0.01). Involving elementary-aged students in the design of vegetable promotional materials that were posted in the lunchroom increased the amount of vegetables students consumed.

  18. Potential Involvement of P2 Receptors in the Pathological Processes of Hyperthyroidism: A Pilot Study.

    Science.gov (United States)

    Hong, Wu; Li, Guodong; Nie, Yijun; Zou, Lifang; Zhang, Xi; Liu, Shuangmei; Li, Guilin; Xu, Hong; Zhang, Chun-Ping; Liang, Shangdong

    2016-05-01

    Symptoms of hyperthyroidism manifest mainly as changes in the nervous and metabolic systems. Whether P2X receptors (ionotropic ATP purinergic receptors, including P2X3 receptor and P2X7 receptor) are involved in the alterations of these disorders still remains unclear. Thus, this study aimed to assess the association of hyperthyroidism with the expression of P2X3 and P2X7 receptors and the concentrations of ATP in blood leukocytes and catecholamine. Twelve healthy subjects and twelve patients diagnosed with hyperthyroidism were recruited. Serum free triiodothyronine (FT3), free thyroxine (FT4) and thyroid stimulating hormone (TSH) levels had been detected by chemiluminescence method. Meanwhile, the catecholamine levels (including adrenaline, noradrenaline, and dopamine) in plasma, ATP level and P2X receptors (including P2X3 receptor and P2X7 receptor) in peripheral blood had been detected by high performance liquid chromatography, bioluminescence method, and reverse transcription polymerase chain reaction, respectively. Levels of epinephrine and norepinephrine were significantly higher in the hyperthyroidism group compared with the control group. The concentration of ATP in the hyperthyroidism group was significantly higher than its in the control group. The expression of P2X3 mRNA and P2X7 mRNA in hyperthyroidism group were significantly increased compared with those in control group. In a conclusion, there is a relationship between the elevated expression of P2X3 receptor and P2X7 receptor in peripheral blood leukocytes and high serum epinephrine and norepinephrine levels in hyperthyroidism patients. © 2016 by the Association of Clinical Scientists, Inc.

  19. Investigation of a separation process involving liquid-water-coal systems

    Energy Technology Data Exchange (ETDEWEB)

    Keller, Jr, D V; Burry, W

    1987-01-01

    A liquid-liquid-solid separation procedure wherein a water-oil-coal-mineral matter slurry is allowed to come to equilibrium through mechanical agitation has for many years been applied to the separation of coal from mineral matter. The product is a black cottage cheese-like mass of agglomerated coal particles and oil suspended in the excess water which supports the dispersed mineral matter particles. A liquid bridge model which was proposed by earlier investigators is reviewed critically and used to estimate the free energy per unit area of the separation of coals of different ranks. Observations of the kinetics of the process suggest that the simple liquid bridge model is insufficient, probably due to the heterogeneous surfaces of the coal. An alternative model is proposed. 14 references.

  20. Gamification as a Means to User Involvement in Decision-making Processes for Sustainable Buildings

    DEFF Research Database (Denmark)

    Hansen, Hanne Tine Ring; Knudstrup, Mary-Ann; Skøtt, Stine

    2017-01-01

    of life. Design thinking was used as method to develop a tool that focuses on how to make sustainable strategy development accessible to non-specialists during those critical stages of building design processes when goals and prioritisations are set. The tool is based on an open and editable platform...... and it will be available to the public in the early Summer of 2017. The paper presents how design thinking is used as an engaging research and development methodology, as well as, an introduction to the dialogue and prioritisation tool’s content and format.......User ownership, actors’ and stakeholders’ lack of knowledge is often identified as critical success parameters and barriers when evaluating how well sustainable buildings perform. Recognising that it is impossible to drive sustainable development without the people who pay for sustainable buildings...

  1. Anticonvulsants Teratogenic Mechanism Involves Alteration of Bioelectrically-controlled Processes in the Embryo. A hypothesis

    Science.gov (United States)

    Hernández-Díaz, Sonia; Levin, Michael

    2014-01-01

    Maternal use of anticonvulsants during the first trimester of pregnancy has been associated with an elevated risk of major congenital malformations in the offspring. Whether the increased risk is caused by the specific pharmacological mechanisms of certain anticonvulsants, the underlying epilepsy, or common genetic or environmental risk factors shared by epilepsy and malformations is controversial. We hypothesize that anticonvulsant therapies during pregnancy that attain more successful inhibition of neurotransmission might lead to both better seizure control in the mother and stronger alteration of bioelectrically-controlled processes in the embryo that result in structural malformations. If our theory were correct, development of pharmaceuticals that do not alter cell resting transmembrane voltage levels could result in safer drugs. PMID:24815983

  2. Involvement of DNA methylation in memory processing in the honey bee.

    Science.gov (United States)

    Lockett, Gabrielle A; Helliwell, Paul; Maleszka, Ryszard

    2010-08-23

    DNA methylation, an important and evolutionarily conserved epigenetic mechanism, is implicated in learning and memory processes in vertebrates, but its role in behaviour in invertebrates is unknown. We examined the role of DNA methylation in memory in the honey bee using an appetitive Pavlovian olfactory discrimination task, and by assessing the expression of DNA methyltransferase3, a key driver of epigenetic reprogramming. Here we report that DNA methyltransferase inhibition reduces acquisition retention and alters the extinction depending on treatment time, and DNA methyltransferase3 is upregulated after training. Our findings add to the understanding of epigenetic mechanisms in learning and memory, extending known roles of DNA methylation to appetitive and extinction memory, and for the first time implicate DNA methylation in memory in invertebrates.

  3. Exposures involving perturbations of the EM field have non-linear effects on radiation response and can alter the expression of radiation induced bystander effects

    Science.gov (United States)

    Mothersill, Carmel; Seymour, Colin

    2012-07-01

    Our recent data suggest there is a physical component to the bystander signal induced by radiation exposure and that alternative medicine techniques such as Reiki and acupuncture or exposures to weak EM fields alter the response of cells to direct irradiation and either altered bystander signal production or altered the response of cells receiving bystander signals. Our proposed mechanism to explain these findings is that perturbation of electromagnetic (EM) fields is central to the induction of low radiation dose responses especially non-targeted bystander effects. In this presentation we review the alternative medicine data and other data sets from our laboratory which test our hypothesis that perturbation of bio-fields will modulate radiation response in the low dose region. The other data sets include exposure to MRI, shielding using lead and or Faraday cages, the use of physical barriers to bystander signal transmission and the use of membrane channel blockers. The data taken together strongly suggest that EM field perturbation can modulate low dose response and that in fact the EM field rather than the targeted deposition of ionizing energy in the DNA may be the key determinant of dose response in a cell or organism The results also lead us to suspect that at least when chemical transmission is blocked, bystander signals can be transmitted by other means. Our recent experiments suggest light signals and volatiles are not likely. We conclude that alternative medicine and other techniques involving electromagnetic perturbations can modify the response of cells to low doses of ionizing radiation and can induce bystander effects similar to those seen in medium transfer experiments. In addition to the obvious implications for mechanistic studies of low dose effects, this could perhaps provide a novel target to exploit in space radiation protection and in optimizing therapeutic gain during radiotherapy.

  4. Development of Prescription Drug Information Leaflets: Impact of Cognitive Effort and Patient Involvement on Prescription Medication Information Processing.

    Science.gov (United States)

    Patel, Harshali K; Bapat, Shweta S; Bhansali, Archita H; Sansgiry, Sujit S

    2018-01-01

    The objective of this study was to develop a one-page (1-page) prescription drug information leaflet (PILs) and assess their impact on the information processing variables, across 2 levels of patient involvement. One-page PILs were developed using cognitive principles to lower mental effort and improve comprehension. An experimental, 3 × 2 repeated measures study was conducted to determine the impact of cognitive effort, manipulated using leaflet type on comprehension across 2 levels (high/low) of patient involvement. Adults (≥18 years) in a university setting in Houston were recruited for the study. Each participant was exposed to 3 different types of prescription drug information leaflet (the current practice, preexisting 1-page text-only, and 1-page PILs) for the 3 drugs (Celebrex, Ventolin HFA, Prezista) for a given involvement scenario. A prevalidated survey instrument was used to measure product knowledge, attitude toward leaflet, and intention to read. Multivariate analysis of variance indicated significant positive effect of cognitive effort, involvement, and their interaction effect across all measured variables. Mean scores for product knowledge, attitude toward leaflet, and intention to read were highest for PILs ( P information processing for consumers by reducing their cognitive effort.

  5. The Public Health Service guidelines. Governing research involving human subjects: An analysis of the policy-making process

    Science.gov (United States)

    Frankel, M. S.

    1972-01-01

    The policy making process which led to development of the Public Health Service Guidelines governing research involving human subjects is outlined. Part 1 examines the evolution of PHS Guidelines, tracing (1) evolution of thought and legal interpretation regarding research using human subjects; (2) initial involvement of the Federal government; (3) development of the government's research program; (4) the social-political environment in which formal government policy was developed; and (5) various policy statements issued by the government. Part 2 analyzes the process by which PHS Guidelines were developed and examines the values and other underlying factors which contributed to their development. It was concluded that the evolution of the Guidelines is best understood within the context of a mixed-scanning strategy. In such a strategy, policy makers make fundamental decisions regarding the basic direction of policy and subsequent decisions are made incrementally and within the contexts set by the original fundamental decisions.

  6. Demonstrating the unit hydrograph and flow routing processes involving active student participation - a university lecture experiment

    Science.gov (United States)

    Schulz, Karsten; Burgholzer, Reinhard; Klotz, Daniel; Wesemann, Johannes; Herrnegger, Mathew

    2018-05-01

    The unit hydrograph (UH) has been one of the most widely employed hydrological modelling techniques to predict rainfall-runoff behaviour of hydrological catchments, and is still used to this day. Its concept is based on the idea that a unit of effective precipitation per time unit (e.g. mm h-1) will always lead to a specific catchment response in runoff. Given its relevance, the UH is an important topic that is addressed in most (engineering) hydrology courses at all academic levels. While the principles of the UH seem to be simple and easy to understand, teaching experiences in the past suggest strong difficulties in students' perception of the UH theory and application. In order to facilitate a deeper understanding of the theory and application of the UH for students, we developed a simple and cheap lecture theatre experiment which involved active student participation. The seating of the students in the lecture theatre represented the hydrological catchment in its size and form. A set of plastic balls, prepared with a piece of magnetic strip to be tacked to any white/black board, each represented a unit amount of effective precipitation. The balls are evenly distributed over the lecture theatre and routed by some given rules down the catchment to the catchment outlet, where the resulting hydrograph is monitored and illustrated at the black/white board. The experiment allowed an illustration of the underlying principles of the UH, including stationarity, linearity, and superposition of the generated runoff and subsequent routing. In addition, some variations of the experimental setup extended the UH concept to demonstrate the impact of elevation, different runoff regimes, and non-uniform precipitation events on the resulting hydrograph. In summary, our own experience in the classroom, a first set of student exams, as well as student feedback and formal evaluation suggest that the integration of such an experiment deepened the learning experience by active

  7. Nonlinear optics

    CERN Document Server

    Boyd, Robert W

    2013-01-01

    Nonlinear Optics is an advanced textbook for courses dealing with nonlinear optics, quantum electronics, laser physics, contemporary and quantum optics, and electrooptics. Its pedagogical emphasis is on fundamentals rather than particular, transitory applications. As a result, this textbook will have lasting appeal to a wide audience of electrical engineering, physics, and optics students, as well as those in related fields such as materials science and chemistry.Key Features* The origin of optical nonlinearities, including dependence on the polarization of light* A detailed treatment of the q

  8. A new automated assessment method for contrast–detail images by applying support vector machine and its robustness to nonlinear image processing

    International Nuclear Information System (INIS)

    Takei, Takaaki; Ikeda, Mitsuru; Imai, Kumiharu; Yamauchi-Kawaura, Chiyo; Kato, Katsuhiko; Isoda, Haruo

    2013-01-01

    The automated contrast–detail (C–D) analysis methods developed so-far cannot be expected to work well on images processed with nonlinear methods, such as noise reduction methods. Therefore, we have devised a new automated C–D analysis method by applying support vector machine (SVM), and tested for its robustness to nonlinear image processing. We acquired the CDRAD (a commercially available C–D test object) images at a tube voltage of 120 kV and a milliampere-second product (mAs) of 0.5–5.0. A partial diffusion equation based technique was used as noise reduction method. Three radiologists and three university students participated in the observer performance study. The training data for our SVM method was the classification data scored by the one radiologist for the CDRAD images acquired at 1.6 and 3.2 mAs and their noise-reduced images. We also compared the performance of our SVM method with the CDRAD Analyser algorithm. The mean C–D diagrams (that is a plot of the mean of the smallest visible hole diameter vs. hole depth) obtained from our devised SVM method agreed well with the ones averaged across the six human observers for both original and noise-reduced CDRAD images, whereas the mean C–D diagrams from the CDRAD Analyser algorithm disagreed with the ones from the human observers for both original and noise-reduced CDRAD images. In conclusion, our proposed SVM method for C–D analysis will work well for the images processed with the non-linear noise reduction method as well as for the original radiographic images.

  9. A new automated assessment method for contrast-detail images by applying support vector machine and its robustness to nonlinear image processing.

    Science.gov (United States)

    Takei, Takaaki; Ikeda, Mitsuru; Imai, Kuniharu; Yamauchi-Kawaura, Chiyo; Kato, Katsuhiko; Isoda, Haruo

    2013-09-01

    The automated contrast-detail (C-D) analysis methods developed so-far cannot be expected to work well on images processed with nonlinear methods, such as noise reduction methods. Therefore, we have devised a new automated C-D analysis method by applying support vector machine (SVM), and tested for its robustness to nonlinear image processing. We acquired the CDRAD (a commercially available C-D test object) images at a tube voltage of 120 kV and a milliampere-second product (mAs) of 0.5-5.0. A partial diffusion equation based technique was used as noise reduction method. Three radiologists and three university students participated in the observer performance study. The training data for our SVM method was the classification data scored by the one radiologist for the CDRAD images acquired at 1.6 and 3.2 mAs and their noise-reduced images. We also compared the performance of our SVM method with the CDRAD Analyser algorithm. The mean C-D diagrams (that is a plot of the mean of the smallest visible hole diameter vs. hole depth) obtained from our devised SVM method agreed well with the ones averaged across the six human observers for both original and noise-reduced CDRAD images, whereas the mean C-D diagrams from the CDRAD Analyser algorithm disagreed with the ones from the human observers for both original and noise-reduced CDRAD images. In conclusion, our proposed SVM method for C-D analysis will work well for the images processed with the non-linear noise reduction method as well as for the original radiographic images.

  10. Changes in Pre-service Science Teachers' Understandings After Being Involved in Explicit Nature of Science and Socioscientific Argumentation Processes

    Science.gov (United States)

    Kutluca, A. Y.; Aydın, A.

    2017-08-01

    The study explored the changes in pre-service science teachers' understanding of the nature of science and their opinions about the nature of science, science teaching and argumentation after their participation in explicit nature of science (NOS) and socioscientific argumentation processes. The participants were 56 third-grade pre-service science teachers studying in a state university in Turkey. The treatment group comprised 27 participants, and there were 29 participants in the comparison group. The comparison group participants were involved in a student-centred science-teaching process, and the participants of the treatment group were involved in explicit NOS and socioscientific argumentation processes. In the study, which lasted a total of 11 weeks, a NOS-as-argumentation questionnaire was administered to all the participants to determine their understanding of NOS at the beginning and end of the data collection process, and six random participants of the treatment group participated in semi-structured interview questions in order to further understand their views regarding NOS, science teaching and argumentation. Qualitative and quantitative data analysis revealed that the explicit NOS and socioscientific argumentation processes had a significant effect on pre-service science teachers' NOS understandings. Furthermore, NOS, argumentation and science teaching views of the participants in the treatment group showed a positive change. The results of this study are discussed in light of the related literature, and suggestions are made within the context of contribution to science-teaching literature, improvement of education quality and education of pre-service teachers.

  11. Further dissociating the processes involved in recognition memory: an FMRI study.

    Science.gov (United States)

    Henson, Richard N A; Hornberger, Michael; Rugg, Michael D

    2005-07-01

    Based on an event-related potential study by Rugg et al. [Dissociation of the neural correlates of implicit and explicit memory. Nature, 392, 595-598, 1998], we attempted to isolate the hemodynamic correlates of recollection, familiarity, and implicit memory within a single verbal recognition memory task using event-related fMRI. Words were randomly cued for either deep or shallow processing, and then intermixed with new words for yes/no recognition. The number of studied words was such that, whereas most were recognized ("hits"), an appreciable number of shallow-studied words were not ("misses"). Comparison of deep hits versus shallow hits at test revealed activations in regions including the left inferior parietal gyrus. Comparison of shallow hits versus shallow misses revealed activations in regions including the bilateral intraparietal sulci, the left posterior middle frontal gyrus, and the left frontopolar cortex. Comparison of hits versus correct rejections revealed a relative deactivation in an anterior left medial-temporal region (most likely the perirhinal cortex). Comparison of shallow misses versus correct rejections did not reveal response decreases in any regions expected on the basis of previous imaging studies of priming. Given these and previous data, we associate the left inferior parietal activation with recollection, the left anterior medial-temporal deactivation with familiarity, and the intraparietal and prefrontal responses with target detection. The absence of differences between shallow misses and correct rejections means that the hemodynamic correlates of implicit memory remain unclear.

  12. Plant immunity induced by COS-OGA elicitor is a cumulative process that involves salicylic acid.

    Science.gov (United States)

    van Aubel, Géraldine; Cambier, Pierre; Dieu, Marc; Van Cutsem, Pierre

    2016-06-01

    Plant innate immunity offers considerable opportunities for plant protection but beside flagellin and chitin, not many molecules and their receptors have been extensively characterized and very few have successfully reached the field. COS-OGA, an elicitor that combines cationic chitosan oligomers (COS) with anionic pectin oligomers (OGA), efficiently protected tomato (Solanum lycopersicum) grown in greenhouse against powdery mildew (Leveillula taurica). Leaf proteomic analysis of plants sprayed with COS-OGA showed accumulation of Pathogenesis-Related proteins (PR), especially subtilisin-like proteases. qRT-PCR confirmed upregulation of PR-proteins and salicylic acid (SA)-related genes while expression of jasmonic acid/ethylene-associated genes was not modified. SA concentration and class III peroxidase activity were increased in leaves and appeared to be a cumulative process dependent on the number of sprayings with the elicitor. These results suggest a systemic acquired resistance (SAR) mechanism of action of the COS-OGA elicitor and highlight the importance of repeated applications to ensure efficient protection against disease. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  13. Concepts in context: Processing mental state concepts with internal or external focus involves different neural systems

    Science.gov (United States)

    Oosterwijk, Suzanne; Mackey, Scott; Wilson-Mendenhall, Christine; Winkielman, Piotr; Paulus, Martin P.

    2015-01-01

    According to embodied cognition theories concepts are contextually-situated and grounded in neural systems that produce experiential states. This view predicts that processing mental state concepts recruits neural regions associated with different aspects of experience depending on the context in which people understand a concept. This neuroimaging study tested this prediction using a set of sentences that described emotional (e.g., fear, joy) and non-emotional (e.g., thinking, hunger) mental states with internal focus (i.e. focusing on bodily sensations and introspection) or external focus (i.e. focusing on expression and action). Consistent with our predictions, data suggested that the inferior frontal gyrus, a region associated with action representation, was engaged more by external than internal sentences. By contrast, the ventromedial prefrontal cortex, a region associated with the generation of internal states, was engaged more by internal emotion sentences than external sentence categories. Similar patterns emerged when we examined the relationship between neural activity and independent ratings of sentence focus. Furthermore, ratings of emotion were associated with activation in the medial prefrontal cortex, whereas ratings of activity were associated with activation in the inferior frontal gyrus. These results suggest that mental state concepts are represented in a dynamic way, using context-relevant interoceptive and sensorimotor resources. PMID:25748274

  14. Key process parameters involved in the treatment of olive mill wastewater by membrane bioreactor.

    Science.gov (United States)

    Jaouad, Y; Villain-Gambier, M; Mandi, L; Marrot, B; Ouazzani, N

    2018-04-18

    The Olive Mill Wastewater (OMWW) biodegradation in an external ceramic membrane bioreactor (MBR) was investigated with a starting acclimation step with a Ultrafiltration (UF) membrane (150 kDa) and no sludge discharge in order to develop a specific biomass adapted to OMWW biodegradation. After acclimation step, UF was replaced by an Microfiltration (MF) membrane (0.1 µm). Sludge Retention Time (SRT) was set around 25 days and Food to Microorganisms ratio (F/M) was fixed at 0.2 kg COD  kg MLVSS -1  d -1 . At stable state, removal of the main phenolic compounds (hydroxytyrosol and tyrosol) and Chemical Oxygen Demand (COD) were successfully reached (95% both). Considered as a predominant fouling factor, but never quantified in MBR treated OMWW, Soluble Microbial Products (SMP) proteins, polysaccharides and humic substances concentrations were determined (80, 110 and 360 mg L -1 respectively). At the same time, fouling was easily managed due to favourable hydraulic conditions of external ceramic MBR. Therefore, OMWW could be efficiently and durably treated by an MF MBR process under adapted operating parameters.

  15. Studies of the mechanisms involved in the laser surface hardening process of aluminum base alloys

    International Nuclear Information System (INIS)

    Silva, Luciana Ventavele da

    2011-01-01

    The Al-Si alloys are widely used in industry to replace the steel and gray cast iron in high-tech sectors. The commercial importance of these alloys is mainly due to its low weight, excellent wear (abrasion) and corrosion resistance, high resistance at elevated temperatures, low coefficient of thermal expansion and lesser fuel consumption that provide considerable reduction of emission of pollutants. In this work, Al-Si alloy used in the automotive industry to manufacture pistons of internal combustion engines, was undergone to surface treatments using LASER remelting (Nd:YAG, λ = 1.06 μm, pulsed mode). The LASER enables various energy concentrations with accurate transfer to the material without physical contact. The intense energy transfer causes the occurrence of structural changes in the superficial layer of the material. Experiments with single pulses and trails were conducted under various conditions of LASER processing in order to analyze microstructural changes resulting from treatments and their effects on the hardness. For the characterization of hardened layer was utilized the following techniques: optical microscopy, scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), x-ray mapping, Vickers microhardness and maximum roughness tests. The high cooling rate caused a change in the alloy structure due to the refinement of the primary eutectic silicon particles, resulting in increase of the mechanical properties (hardness) of the Al-Si alloy. (author)

  16. Direct Urca Processes Involving Proton 1 S 0 Superfluidity in Neutron Star Cooling

    Science.gov (United States)

    Xu, Yan; Yu, Zi; Zhang, Xiao-Jun; Fan, Cun-Bo; Liu, Guang-Zhou; Zhao, En-Guang; Huang, Xiu-Lin; Liu, Cheng-Zhi

    2018-04-01

    A detailed description of the baryon direct Urca processes A: n\\to p+e+{\\bar{ν }}e, B: Λ \\to p+e+{\\bar{ν }}e and C: {\\Xi }-\\to Λ +e+{\\bar{ν }}e related to the neutron star cooling is given in the relativistic mean field approximation. The contributions of the reactions B and C on the neutrino luminosity are calculated by means of the relativistic expressions of the neutrino energy losses. Our results show that the total neutrino luminosities of the reactions A, B and C within the mass range (1.603–2.067) M⊙ ((1.515–1.840) M⊙ for TM1 model) for GM1 model are larger than the corresponding values for neutron star without hyperons. Furthermore, although the neutrino emissivity of the reaction A is suppressed with the appearance of the proton 1 S 0 superfluid, the contribution of the reactions B and C can still quicken a massive neutron star cooling. In particular, the reaction C in PSR J1614-2230 and J0348+0432 is not suppressed by the proton 1 S 0 superfluid due to the higher threshold density of the reaction C, which will further speed up the two pulsars cooling. Supported by the National Natural Science Foundation of China under Grant Nos. 11447165, 11373047, 11404336 and U1731240, Youth Innovation Promotion Association, CAS under Grant No. 2016056, and the Development Project of Science and Technology of Jilin Province under Grant No. 20180520077JH

  17. Ultrafast nonlinear optics

    CERN Document Server

    Leburn, Christopher; Reid, Derryck

    2013-01-01

    The field of ultrafast nonlinear optics is broad and multidisciplinary, and encompasses areas concerned with both the generation and measurement of ultrashort pulses of light, as well as those concerned with the applications of such pulses. Ultrashort pulses are extreme events – both in terms of their durations, and also the high peak powers which their short durations can facilitate. These extreme properties make them powerful experiment tools. On one hand, their ultrashort durations facilitate the probing and manipulation of matter on incredibly short timescales. On the other, their ultrashort durations can facilitate high peak powers which can drive highly nonlinear light-matter interaction processes. Ultrafast Nonlinear Optics covers a complete range of topics, both applied and fundamental in nature, within the area of ultrafast nonlinear optics. Chapters 1 to 4 are concerned with the generation and measurement of ultrashort pulses. Chapters 5 to 7 are concerned with fundamental applications of ultrasho...

  18. A semi-analytical finite element process for nonlinear elastoplastic analysis of arbitrarily loaded shells of revolution

    International Nuclear Information System (INIS)

    Rensch, H.J.; Wunderlich, W.

    1981-01-01

    The governing partial differential equations used are valid for small strains and moderate rotations. Plasticity relations are based on J 2 -flow theory. In order to eliminate the circumferential coordinate, the loading as well as the unkown quantities are expanded in Fourier series in the circumferential direction. The nonlinear terms due to moderate rotations and plastic deformations are treated as pseudo load quantities. In this way, the governing equations can be reduced to uncoupled systems of first-order ordinary differential equations in the meridional direction. They are then integrated over a shell segment via a matrix series expansion. The resulting element transfer matrices are transformed into stiffness matrices, and for the analysis of the total structure the finite element method is employed. Thus, arbitrary branching of the shell geometry is possible. Compared to two-dimensional approximations, the major advantage of the semi-analytical procedure is that the structural stiffness matrix usually has a small handwidth, resulting in shorter computer run times. Moreover, its assemblage and triangularization has to be carried out only once bacause all nonlinear effects are treated as initial loads. (orig./HP)

  19. Nonlinear systems

    National Research Council Canada - National Science Library

    Drazin, P. G

    1992-01-01

    This book is an introduction to the theories of bifurcation and chaos. It treats the solution of nonlinear equations, especially difference and ordinary differential equations, as a parameter varies...

  20. Nonlinear analysis

    CERN Document Server

    Gasinski, Leszek

    2005-01-01

    Hausdorff Measures and Capacity. Lebesgue-Bochner and Sobolev Spaces. Nonlinear Operators and Young Measures. Smooth and Nonsmooth Analysis and Variational Principles. Critical Point Theory. Eigenvalue Problems and Maximum Principles. Fixed Point Theory.

  1. Psychopathological Processes Involved in Social Comparison, Depression, and Envy on Facebook

    Directory of Open Access Journals (Sweden)

    Aurel Pera

    2018-01-01

    Full Text Available Is Facebook utilization beneficial or detrimental for psychological well-being? I draw on outstanding research (e.g., Chou and Edge, 2012; Lin and Utz, 2015; Appel et al., 2016; Ehrenreich and Underwood, 2016; Vogel and Rose, 2016; Hu et al., 2017 to substantiate that examining other individuals’ positively presented material on Facebook may have detrimental consequences. Increasing comparisons on Facebook may generate feelings of envy, the latter being a significant process determining the effect of growing social comparison on psychological well-being. To date, there is an increasing body of literature investigating the psychological consequences of Facebook usage, the function of relationship closeness in producing the feelings of contentment and envy, the impacts of exposure to positive content on Facebook, the link between envy and depression on Facebook, and the function of tie strength in expecting the emotional results of browsing Facebook. I am specifically interested in how previous research explored the consequences of Facebook use on psychological outcomes, the moderating function of envy in the link between Facebook use and reduced affective wellbeing, the psychological results of non-interactive Facebook conduct, and the role of relationship closeness in anticipating user’s contentment and envy after inspecting a post. A synthesis of the extant literature suggests that inspecting other individuals’ positive news on Facebook brings about contentment through emotional contagion, whereas negative news causes discomfort as a consequence of mood contagion, the transmissible effect being more powerful when the news is associated with a strong tie. The outcomes of this research back the argument that self-confidence and dispositional envy are instrumental in producing Facebook envy. These findings highlight that the emotional results of browsing Facebook are considerably affected by the substance of the comment, the personal

  2. Psychopathological Processes Involved in Social Comparison, Depression, and Envy on Facebook.

    Science.gov (United States)

    Pera, Aurel

    2018-01-01

    Is Facebook utilization beneficial or detrimental for psychological well-being? I draw on outstanding research (e.g., Chou and Edge, 2012; Lin and Utz, 2015; Appel et al., 2016; Ehrenreich and Underwood, 2016; Vogel and Rose, 2016; Hu et al., 2017) to substantiate that examining other individuals' positively presented material on Facebook may have detrimental consequences. Increasing comparisons on Facebook may generate feelings of envy, the latter being a significant process determining the effect of growing social comparison on psychological well-being. To date, there is an increasing body of literature investigating the psychological consequences of Facebook usage, the function of relationship closeness in producing the feelings of contentment and envy, the impacts of exposure to positive content on Facebook, the link between envy and depression on Facebook, and the function of tie strength in expecting the emotional results of browsing Facebook. I am specifically interested in how previous research explored the consequences of Facebook use on psychological outcomes, the moderating function of envy in the link between Facebook use and reduced affective wellbeing, the psychological results of non-interactive Facebook conduct, and the role of relationship closeness in anticipating user's contentment and envy after inspecting a post. A synthesis of the extant literature suggests that inspecting other individuals' positive news on Facebook brings about contentment through emotional contagion, whereas negative news causes discomfort as a consequence of mood contagion, the transmissible effect being more powerful when the news is associated with a strong tie. The outcomes of this research back the argument that self-confidence and dispositional envy are instrumental in producing Facebook envy. These findings highlight that the emotional results of browsing Facebook are considerably affected by the substance of the comment, the personal attributes of the Facebook user

  3. Psychopathological Processes Involved in Social Comparison, Depression, and Envy on Facebook

    Science.gov (United States)

    Pera, Aurel

    2018-01-01

    Is Facebook utilization beneficial or detrimental for psychological well-being? I draw on outstanding research (e.g., Chou and Edge, 2012; Lin and Utz, 2015; Appel et al., 2016; Ehrenreich and Underwood, 2016; Vogel and Rose, 2016; Hu et al., 2017) to substantiate that examining other individuals’ positively presented material on Facebook may have detrimental consequences. Increasing comparisons on Facebook may generate feelings of envy, the latter being a significant process determining the effect of growing social comparison on psychological well-being. To date, there is an increasing body of literature investigating the psychological consequences of Facebook usage, the function of relationship closeness in producing the feelings of contentment and envy, the impacts of exposure to positive content on Facebook, the link between envy and depression on Facebook, and the function of tie strength in expecting the emotional results of browsing Facebook. I am specifically interested in how previous research explored the consequences of Facebook use on psychological outcomes, the moderating function of envy in the link between Facebook use and reduced affective wellbeing, the psychological results of non-interactive Facebook conduct, and the role of relationship closeness in anticipating user’s contentment and envy after inspecting a post. A synthesis of the extant literature suggests that inspecting other individuals’ positive news on Facebook brings about contentment through emotional contagion, whereas negative news causes discomfort as a consequence of mood contagion, the transmissible effect being more powerful when the news is associated with a strong tie. The outcomes of this research back the argument that self-confidence and dispositional envy are instrumental in producing Facebook envy. These findings highlight that the emotional results of browsing Facebook are considerably affected by the substance of the comment, the personal attributes of the Facebook

  4. On some applications of diffusion processes for image processing

    International Nuclear Information System (INIS)

    Morfu, S.

    2009-01-01

    We propose a new algorithm inspired by the properties of diffusion processes for image filtering. We show that purely nonlinear diffusion processes ruled by Fisher equation allows contrast enhancement and noise filtering, but involves a blurry image. By contrast, anisotropic diffusion, described by Perona and Malik algorithm, allows noise filtering and preserves the edges. We show that combining the properties of anisotropic diffusion with those of nonlinear diffusion provides a better processing tool which enables noise filtering, contrast enhancement and edge preserving.

  5. Statistical process control charts for attribute data involving very large sample sizes: a review of problems and solutions.

    Science.gov (United States)

    Mohammed, Mohammed A; Panesar, Jagdeep S; Laney, David B; Wilson, Richard

    2013-04-01

    The use of statistical process control (SPC) charts in healthcare is increasing. The primary purpose of SPC is to distinguish between common-cause variation which is attributable to the underlying process, and special-cause variation which is extrinsic to the underlying process. This is important because improvement under common-cause variation requires action on the process, whereas special-cause variation merits an investigation to first find the cause. Nonetheless, when dealing with attribute or count data (eg, number of emergency admissions) involving very large sample sizes, traditional SPC charts often produce tight control limits with most of the data points appearing outside the control limits. This can give a false impression of common and special-cause variation, and potentially misguide the user into taking the wrong actions. Given the growing availability of large datasets from routinely collected databases in healthcare, there is a need to present a review of this problem (which arises because traditional attribute charts only consider within-subgroup variation) and its solutions (which consider within and between-subgroup variation), which involve the use of the well-established measurements chart and the more recently developed attribute charts based on Laney's innovative approach. We close by making some suggestions for practice.

  6. Using a Virtual Tablet Machine to Improve Student Understanding of the Complex Processes Involved in Tablet Manufacturing.

    Science.gov (United States)

    Mattsson, Sofia; Sjöström, Hans-Erik; Englund, Claire

    2016-06-25

    Objective. To develop and implement a virtual tablet machine simulation to aid distance students' understanding of the processes involved in tablet production. Design. A tablet simulation was created enabling students to study the effects different parameters have on the properties of the tablet. Once results were generated, students interpreted and explained them on the basis of current theory. Assessment. The simulation was evaluated using written questionnaires and focus group interviews. Students appreciated the exercise and considered it to be motivational. Students commented that they found the simulation, together with the online seminar and the writing of the report, was beneficial for their learning process. Conclusion. According to students' perceptions, the use of the tablet simulation contributed to their understanding of the compaction process.

  7. Differential involvement of glutamate-gated chloride channel splice variants in the olfactory memory processes of the honeybee Apis mellifera.

    Science.gov (United States)

    Démares, Fabien; Drouard, Florian; Massou, Isabelle; Crattelet, Cindy; Lœuillet, Aurore; Bettiol, Célia; Raymond, Valérie; Armengaud, Catherine

    2014-09-01

    Glutamate-gated chloride channels (GluCl) belong to the cys-loop ligand-gated ion channel superfamily and their expression had been described in several invertebrate nervous systems. In the honeybee, a unique gene amel_glucl encodes two alternatively spliced subunits, Amel_GluCl A and Amel_GluCl B. The expression and differential localization of those variants in the honeybee brain had been previously reported. Here we characterized the involvement of each variant in olfactory learning and memory processes, using specific small-interfering RNA (siRNA) targeting each variant. Firstly, the efficacy of the two siRNAs to decrease their targets' expression was tested, both at mRNA and protein levels. The two proteins showed a decrease of their respective expression 24h after injection. Secondly, each siRNA was injected into the brain to test whether or not it affected olfactory memory by using a classical paradigm of conditioning the proboscis extension reflex (PER). Amel_GluCl A was found to be involved only in retrieval of 1-nonanol, whereas Amel_GluCl B was involved in the PER response to 2-hexanol used as a conditioned stimulus or as new odorant. Here for the first time, a differential behavioral involvement of two highly similar GluCl subunits has been characterized in an invertebrate species. Copyright © 2014 Elsevier Inc. All rights reserved.

  8. Applications of nonlinear fiber optics

    CERN Document Server

    Agrawal, Govind

    2008-01-01

    * The only book describing applications of nonlinear fiber optics * Two new chapters on the latest developments: highly nonlinear fibers and quantum applications* Coverage of biomedical applications* Problems provided at the end of each chapterThe development of new highly nonlinear fibers - referred to as microstructured fibers, holey fibers and photonic crystal fibers - is the next generation technology for all-optical signal processing and biomedical applications. This new edition has been thoroughly updated to incorporate these key technology developments.The bo

  9. Linear and non-linear optics of condensed matter

    International Nuclear Information System (INIS)

    McLean, T.P.

    1977-01-01

    Part I - Linear optics: 1. General introduction. 2. Frequency dependence of epsilon(ω, k vector). 3. Wave-vector dependence of epsilon(ω, k vector). 4. Tensor character of epsilon(ω, k vector). Part II - Non-linear optics: 5. Introduction. 6. A classical theory of non-linear response in one dimension. 7. The generalization to three dimensions. 8. General properties of the polarizability tensors. 9. The phase-matching condition. 10. Propagation in a non-linear dielectric. 11. Second harmonic generation. 12. Coupling of three waves. 13. Materials and their non-linearities. 14. Processes involving energy exchange with the medium. 15. Two-photon absorption. 16. Stimulated Raman effect. 17. Electro-optic effects. 18. Limitations of the approach presented here. (author)

  10. Nonlinear Multiantenna Detection Methods

    Directory of Open Access Journals (Sweden)

    Chen Sheng

    2004-01-01

    Full Text Available A nonlinear detection technique designed for multiple-antenna assisted receivers employed in space-division multiple-access systems is investigated. We derive the optimal solution of the nonlinear spatial-processing assisted receiver for binary phase shift keying signalling, which we refer to as the Bayesian detector. It is shown that this optimal Bayesian receiver significantly outperforms the standard linear beamforming assisted receiver in terms of a reduced bit error rate, at the expense of an increased complexity, while the achievable system capacity is substantially enhanced with the advent of employing nonlinear detection. Specifically, when the spatial separation expressed in terms of the angle of arrival between the desired and interfering signals is below a certain threshold, a linear beamformer would fail to separate them, while a nonlinear detection assisted receiver is still capable of performing adequately. The adaptive implementation of the optimal Bayesian detector can be realized using a radial basis function network. Two techniques are presented for constructing block-data-based adaptive nonlinear multiple-antenna assisted receivers. One of them is based on the relevance vector machine invoked for classification, while the other on the orthogonal forward selection procedure combined with the Fisher ratio class-separability measure. A recursive sample-by-sample adaptation procedure is also proposed for training nonlinear detectors based on an amalgam of enhanced -means clustering techniques and the recursive least squares algorithm.

  11. Introduction to nonlinear acoustics

    Science.gov (United States)

    Bjørnø, Leif

    2010-01-01

    A brief review of the basic principles of fluid mechanics needed for development of linear and nonlinear ultrasonic concepts will be given. The fundamental equations of nonlinear ultrasonics will be derived and their physical properties explained. It will be shown how an originally monochromatic finite-amplitude ultrasonic wave, due to nonlinear effects, will distort during its propagation in time and space to form higher harmonics to its fundamental frequency. The concepts of shock formation will be presented. The material nonlinearity, described by the nonlinearity parameter B/A of the material, and the convective nonlinearity, described by the ultrasonic Mach Number, will be explained. Two procedures for determination of B/A will briefly be described and some B/A-values characterizing biological materials will be presented. Shock formation, described by use of the Goldberg Number,and Ultrasonic Saturation will be discussed.. An introduction to focused ultrasonic fields will be given and it will be shown how the ultrasonic intensity will vary axially and laterally in and near the focal region and how the field parameters of interest to biomedical applications may be described by use of the KZK-Model. Finally, an introduction will be given to the parametric acoustic array formed by mixing and interaction of two monochromatic, finite-amplitude ultrasonic waves in a liquid and the potentials of this mixing process in biomedical ultrasound will briefly be mentioned.

  12. A Proteomic Approach for the Identification of Up-Regulated Proteins Involved in the Metabolic Process of the Leiomyoma.

    Science.gov (United States)

    Ura, Blendi; Scrimin, Federica; Arrigoni, Giorgio; Franchin, Cinzia; Monasta, Lorenzo; Ricci, Giuseppe

    2016-04-09

    Uterine leiomyoma is the most common benign smooth muscle cell tumor of the uterus. Proteomics is a powerful tool for the analysis of complex mixtures of proteins. In our study, we focused on proteins that were upregulated in the leiomyoma compared to the myometrium. Paired samples of eight leiomyomas and adjacent myometrium were obtained and submitted to two-dimensional gel electrophoresis (2-DE) and mass spectrometry for protein identification and to Western blotting for 2-DE data validation. The comparison between the patterns revealed 24 significantly upregulated (p leiomyoma and not with the normal myometrium. The overexpression of seven proteins involved in the metabolic processes of the leiomyoma was further validated by Western blotting and 2D Western blotting. Four of these proteins have never been associated with the leiomyoma before. The 2-DE approach coupled with mass spectrometry, which is among the methods of choice for comparative proteomic studies, identified a number of proteins overexpressed in the leiomyoma and involved in several biological processes, including metabolic processes. A better understanding of the mechanism underlying the overexpression of these proteins may be important for therapeutic purposes.

  13. The posterior medial cortex is involved in visual but not in verbal memory encoding processing: an intracerebral recording study.

    Science.gov (United States)

    Stillová, K; Jurák, P; Chládek, J; Halámek, J; Telecká, S; Rektor, I

    2013-03-01

    The objective is to study the involvement of the posterior medial cortex (PMC) in encoding and retrieval by visual and auditory memory processing. Intracerebral recordings were studied in two epilepsy-surgery candidates with depth electrodes implanted in the retrosplenial cingulate, precuneus, cuneus, lingual gyrus and hippocampus. We recorded the event-related potentials (ERP) evoked by visual and auditory memory encoding-retrieval tasks. In the hippocampus, ERP were elicited in the encoding and retrieval phases in the two modalities. In the PMC, ERP were recorded in both the encoding and the retrieval visual tasks; in the auditory modality, they were recorded in the retrieval task, but not in the encoding task. In conclusion, the PMC is modality dependent in memory processing. ERP is elicited by memory retrieval, but it is not elicited by auditory encoding memory processing in the PMC. The PMC appears to be involved not only in higher-order top-down cognitive activities but also in more basic, rather than bottom-up activities.

  14. Improving Patient Involvement in the Drug Development Process: Case Study of Potential Applications from an Online Peer Support Network.

    Science.gov (United States)

    Anand, Amrutha; Brandwood, Helen Jane; Jameson Evans, Matt

    2017-11-01

    To date, social media has been used predominantly by the pharmaceutical industry to market products and to gather feedback and comments on products from consumers, a process termed social listening. However, social media has only been used cautiously in the drug development cycle, mainly because of regulations, restrictions on engagement with patients, or a lack of guidelines for social media use from regulatory bodies. Despite this cautious approach, there is a clear drive, from both the industry and consumers, for increased patient participation in various stages of the drug development process. The authors use the example of HealthUnlocked, one of the world's largest health networks, to illustrate the potential applications of online health communities as a means of increasing patient involvement at various stages of the drug development process. Having identified the willingness of the user population to be involved in research, numerous ways to engage users on the platform have been identified and explored. This commentary describes some of these approaches and reports how online health networks that encourage people to share their experiences in managing their health can, in turn, enable rapid patient engagement for clinical research within the constraints of industry regulation. Copyright © 2017 Elsevier HS Journals, Inc. All rights reserved.

  15. Monitoring of the microbial communities involved in the soy sauce manufacturing process by PCR-denaturing gradient gel electrophoresis.

    Science.gov (United States)

    Tanaka, Yasushi; Watanabe, Jun; Mogi, Yoshinobu

    2012-08-01

    Soy sauce is a traditional seasoning produced through the fermentation of soybeans and wheat using microbes. In this study, the microbial communities involved in the soy sauce manufacturing process were analyzed by PCR-Denaturing Gradient Gel Electrophoresis (PCR-DGGE). The bacterial DGGE profile indicated that the bacterial microbes in the koji were Weissella cibaria (Weissella confusa, Weissella kimchii, Weissella salipiscis, Lactobacillus fermentum, Lactobacillus plantarum, Lactobacillus iners, or Streptococcus thermophilus), Staphylococcus gallinarum (or Staphylococcus xylosus), and Staphylococcus kloosii. In addition to these bacteria, Tetragenococcus halophilus was also detected in the mash during lactic acid fermentation. The fungal DGGE profile indicated that the fungal microbes in the koji were not only Aspergillus oryzae but also several yeasts. In the mash, Zygosaccharomyces rouxii appeared in the early fermentation stage, Candida etchellsii (or Candida nodaensis) and Candida versatilis were detected at the middle fermentation stage, and Candida etchellsii was detected at the mature fermentation stage. These results suggest that the microbial communities present during the soy sauce manufacturing process change drastically throughout its production. This is the first report to reveal the microbial communities involved in the soy sauce manufacturing process using a culture-independent method. Crown Copyright © 2012. Published by Elsevier Ltd. All rights reserved.

  16. Multidimensional nonlinear descriptive analysis

    CERN Document Server

    Nishisato, Shizuhiko

    2006-01-01

    Quantification of categorical, or non-numerical, data is a problem that scientists face across a wide range of disciplines. Exploring data analysis in various areas of research, such as the social sciences and biology, Multidimensional Nonlinear Descriptive Analysis presents methods for analyzing categorical data that are not necessarily sampled randomly from a normal population and often involve nonlinear relations. This reference not only provides an overview of multidimensional nonlinear descriptive analysis (MUNDA) of discrete data, it also offers new results in a variety of fields. The first part of the book covers conceptual and technical preliminaries needed to understand the data analysis in subsequent chapters. The next two parts contain applications of MUNDA to diverse data types, with each chapter devoted to one type of categorical data, a brief historical comment, and basic skills peculiar to the data types. The final part examines several problems and then concludes with suggestions for futu...

  17. Situation concerning public information about and involvement in the decision-making processes in the nuclear sector. Final report

    International Nuclear Information System (INIS)

    Gadbois, S.; Heriard Dubreuil, G.; Vaillant, L.; Schneider, T.; Paterson, J.; Dawson, M.; Borg Barthet, J.; Prades, A.; Lopez, M.; Sala, R.

    2007-01-01

    The European Commission Directorate General for Energy and Transport (EC DGTREN) launched a study on 'the situation concerning public information about and involvement in decision-making processes in the nuclear sector' in January 2005. The main goal of this project was to inform the EC DGTREN and interested parties of recent developments in the Member States and to provide opportunities for decision-makers and stakeholders at local, national and EU level to exchange views. This study is based on the analysis of opinion polls, regulation and case studies where public information and involvement are a key dimension in the decision-making process and where innovative approaches have been observed. The research material and proposals were presented and discussed at a workshop with 50 delegates, representing the various stakeholders concerned by nuclear activities in Europe. As testified by recent opinion polls and feedback from case studies, there is a strong public demand for more participation in decision-making processes relating to the environment, and nuclear issues specifically. There is an increasing expectation that the phase of decision-framing which determines the scope and objectives of a regulation or of a decision on an industrial facility, involves not only experts and politics, but also NGOs, independent experts, local actors, etc. This expectation is now supported by significant legislation at EU and national levels, the foundation stone of which is the 'Aarhus Convention on the Access to Information, Public Participation in Decision-Making and Access to Justice in Environmental Matters' (1998). One can find different but convergent rationales behind these developments. On the one hand, there is a consideration that nuclear technologies have a potential impact on the public and accordingly require that their development involves affected parties. On the other hand, the problems raised by nuclear activities have an impact at several levels (local

  18. Involving private persons and corporations in the planning process according to paragraph 9b German nuclear law - practicability and limits

    International Nuclear Information System (INIS)

    Altmann, J.; Roesel, H.

    1978-01-01

    The 4th Amendment to the German Nuclear Law has procured the legal base for the disposal of radioactive waste in the German Federal Republic. The Nuclear Law states that the Physikalisch-Technische Bundesanstalt (PTB) in Braunschweig is responsible for the disposal of radioactive waste. The PTB can be assisted in its responsibilities by persons and institutions of private character. Involving private persons and corporations in the licensing process figures a legal problem, and there has been a seminar in the PTB discussing such problems. The present contribution gives a brief summary of the opinions stated by the various legal experts taking part in this seminar. (orig./HP) [de

  19. Situation concerning public information about and involvement in the decision-making processes in the nuclear sector. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Gadbois, S.; Heriard Dubreuil, G. [Mutadis, 75 - Paris (France); Vaillant, L.; Schneider, T. [Centre d' Etude sur l' Evaluation de la Protection dans le Domaine Nucleaire - CEPN, 92 - Fontenay aux Roses (France); Paterson, J.; Dawson, M.; Borg Barthet, J. [Aberdeen Univ. (United Kingdom); Prades, A.; Lopez, M.; Sala, R. [CIEMAT, Barcelona (Spain)

    2007-07-01

    The European Commission Directorate General for Energy and Transport (EC DGTREN) launched a study on 'the situation concerning public information about and involvement in decision-making processes in the nuclear sector' in January 2005. The main goal of this project was to inform the EC DGTREN and interested parties of recent developments in the Member States and to provide opportunities for decision-makers and stakeholders at local, national and EU level to exchange views. This study is based on the analysis of opinion polls, regulation and case studies where public information and involvement are a key dimension in the decision-making process and where innovative approaches have been observed. The research material and proposals were presented and discussed at a workshop with 50 delegates, representing the various stakeholders concerned by nuclear activities in Europe. As testified by recent opinion polls and feedback from case studies, there is a strong public demand for more participation in decision-making processes relating to the environment, and nuclear issues specifically. There is an increasing expectation that the phase of decision-framing which determines the scope and objectives of a regulation or of a decision on an industrial facility, involves not only experts and politics, but also NGOs, independent experts, local actors, etc. This expectation is now supported by significant legislation at EU and national levels, the foundation stone of which is the 'Aarhus Convention on the Access to Information, Public Participation in Decision-Making and Access to Justice in Environmental Matters' (1998). One can find different but convergent rationales behind these developments. On the one hand, there is a consideration that nuclear technologies have a potential impact on the public and accordingly require that their development involves affected parties. On the other hand, the problems raised by nuclear activities have an impact at several

  20. Brain network involved in visual processing of movement stimuli used in upper limb robotic training: an fMRI study.

    Science.gov (United States)

    Nocchi, Federico; Gazzellini, Simone; Grisolia, Carmela; Petrarca, Maurizio; Cannatà, Vittorio; Cappa, Paolo; D'Alessio, Tommaso; Castelli, Enrico

    2012-07-24

    The potential of robot-mediated therapy and virtual reality in neurorehabilitation is becoming of increasing importance. However, there is limited information, using neuroimaging, on the neural networks involved in training with these technologies. This study was intended to detect the brain network involved in the visual processing of movement during robotic training. The main aim was to investigate the existence of a common cerebral network able to assimilate biological (human upper limb) and non-biological (abstract object) movements, hence testing the suitability of the visual non-biological feedback provided by the InMotion2 Robot. A visual functional Magnetic Resonance Imaging (fMRI) task was administered to 22 healthy subjects. The task required observation and retrieval of motor gestures and of the visual feedback used in robotic training. Functional activations of both biological and non-biological movements were examined to identify areas activated in both conditions, along with differential activity in upper limb vs. abstract object trials. Control of response was also tested by administering trials with congruent and incongruent reaching movements. The observation of upper limb and abstract object movements elicited similar patterns of activations according to a caudo-rostral pathway for the visual processing of movements (including specific areas of the occipital, temporal, parietal, and frontal lobes). Similarly, overlapping activations were found for the subsequent retrieval of the observed movement. Furthermore, activations of frontal cortical areas were associated with congruent trials more than with the incongruent ones. This study identified the neural pathway associated with visual processing of movement stimuli used in upper limb robot-mediated training and investigated the brain's ability to assimilate abstract object movements with human motor gestures. In both conditions, activations were elicited in cerebral areas involved in visual

  1. Brain network involved in visual processing of movement stimuli used in upper limb robotic training: an fMRI study

    Directory of Open Access Journals (Sweden)

    Nocchi Federico

    2012-07-01

    Full Text Available Abstract Background The potential of robot-mediated therapy and virtual reality in neurorehabilitation is becoming of increasing importance. However, there is limited information, using neuroimaging, on the neural networks involved in training with these technologies. This study was intended to detect the brain network involved in the visual processing of movement during robotic training. The main aim was to investigate the existence of a common cerebral network able to assimilate biological (human upper limb and non-biological (abstract object movements, hence testing the suitability of the visual non-biological feedback provided by the InMotion2 Robot. Methods A visual functional Magnetic Resonance Imaging (fMRI task was administered to 22 healthy subjects. The task required observation and retrieval of motor gestures and of the visual feedback used in robotic training. Functional activations of both biological and non-biological movements were examined to identify areas activated in both conditions, along with differential activity in upper limb vs. abstract object trials. Control of response was also tested by administering trials with congruent and incongruent reaching movements. Results The observation of upper limb and abstract object movements elicited similar patterns of activations according to a caudo-rostral pathway for the visual processing of movements (including specific areas of the occipital, temporal, parietal, and frontal lobes. Similarly, overlapping activations were found for the subsequent retrieval of the observed movement. Furthermore, activations of frontal cortical areas were associated with congruent trials more than with the incongruent ones. Conclusions This study identified the neural pathway associated with visual processing of movement stimuli used in upper limb robot-mediated training and investigated the brain’s ability to assimilate abstract object movements with human motor gestures. In both conditions

  2. Cortical gamma activity during auditory tone omission provides evidence for the involvement of oscillatory activity in top-down processing.

    Science.gov (United States)

    Gurtubay, I G; Alegre, M; Valencia, M; Artieda, J

    2006-11-01

    Perception is an active process in which our brains use top-down influences to modulate afferent information. To determine whether this modulation might be based on oscillatory activity, we asked seven subjects to detect a silence that appeared randomly in a rhythmic auditory sequence, counting the number of omissions ("count" task), or responding to each omission with a right index finger extension ("move" task). Despite the absence of physical stimuli, these tasks induced a 'non-phase-locked' gamma oscillation in temporal-parietal areas, providing evidence of intrinsically generated oscillatory activity during top-down processing. This oscillation is probably related to the local neural activation that takes place during the process of stimulus detection, involving the functional comparison between the tones and the absence of stimuli as well as the auditory echoic memory processes. The amplitude of the gamma oscillations was reduced with the repetition of the tasks. Moreover, it correlated positively with the number of correctly detected omissions and negatively with the reaction time. These findings indicate that these oscillations, like others described, may be modulated by attentional processes. In summary, our findings support the active and adaptive concept of brain function that has emerged over recent years, suggesting that the match of sensory information with memory contents generates gamma oscillations.

  3. Nonlinear optimization

    CERN Document Server

    Ruszczynski, Andrzej

    2011-01-01

    Optimization is one of the most important areas of modern applied mathematics, with applications in fields from engineering and economics to finance, statistics, management science, and medicine. While many books have addressed its various aspects, Nonlinear Optimization is the first comprehensive treatment that will allow graduate students and researchers to understand its modern ideas, principles, and methods within a reasonable time, but without sacrificing mathematical precision. Andrzej Ruszczynski, a leading expert in the optimization of nonlinear stochastic systems, integrates the theory and the methods of nonlinear optimization in a unified, clear, and mathematically rigorous fashion, with detailed and easy-to-follow proofs illustrated by numerous examples and figures. The book covers convex analysis, the theory of optimality conditions, duality theory, and numerical methods for solving unconstrained and constrained optimization problems. It addresses not only classical material but also modern top...

  4. Rho family GTP binding proteins are involved in the regulatory volume decrease process in NIH3T3 mouse fibroblasts

    DEFF Research Database (Denmark)

    Pedersen, Stine F; Beisner, Kristine H; Willumsen, Berthe M

    2002-01-01

    The role of Rho GTPases in the regulatory volume decrease (RVD) process following osmotic cell swelling is controversial and has so far only been investigated for the swelling-activated Cl- efflux. We investigated the involvement of RhoA in the RVD process in NIH3T3 mouse fibroblasts, using wild......-type cells and three clones expressing constitutively active RhoA (RhoAV14). RhoAV14 expression resulted in an up to fourfold increase in the rate of RVD, measured by large-angle light scattering. The increase in RVD rate correlated with RhoAV14 expression. RVD in wild-type cells was unaffected by the Rho...

  5. Real-space post-processing correction of thermal drift and piezoelectric actuator nonlinearities in scanning tunneling microscope images

    Science.gov (United States)

    Yothers, Mitchell P.; Browder, Aaron E.; Bumm, Lloyd A.

    2017-01-01

    We have developed a real-space method to correct distortion due to thermal drift and piezoelectric actuator nonlinearities on scanning tunneling microscope images using Matlab. The method uses the known structures typically present in high-resolution atomic and molecularly resolved images as an internal standard. Each image feature (atom or molecule) is first identified in the image. The locations of each feature's nearest neighbors are used to measure the local distortion at that location. The local distortion map across the image is simultaneously fit to our distortion model, which includes thermal drift in addition to piezoelectric actuator hysteresis and creep. The image coordinates of the features and image pixels are corrected using an inverse transform from the distortion model. We call this technique the thermal-drift, hysteresis, and creep transform. Performing the correction in real space allows defects, domain boundaries, and step edges to be excluded with a spatial mask. Additional real-space image analyses are now possible with these corrected images. Using graphite(0001) as a model system, we show lattice fitting to the corrected image, averaged unit cell images, and symmetry-averaged unit cell images. Statistical analysis of the distribution of the image features around their best-fit lattice sites measures the aggregate noise in the image, which can be expressed as feature confidence ellipsoids.

  6. Non-linear interactions determine the impact of sea-level rise on estuarine benthic biodiversity and ecosystem processes.

    Science.gov (United States)

    Yamanaka, Tsuyuko; Raffaelli, David; White, Piran C L

    2013-01-01

    Sea-level rise induced by climate change may have significant impacts on the ecosystem functions and ecosystem services provided by intertidal sediment ecosystems. Accelerated sea-level rise is expected to lead to steeper beach slopes, coarser particle sizes and increased wave exposure, with consequent impacts on intertidal ecosystems. We examined the relationships between abundance, biomass, and community metabolism of benthic fauna with beach slope, particle size and exposure, using samples across a range of conditions from three different locations in the UK, to determine the significance of sediment particle size beach slope and wave exposure in affecting benthic fauna and ecosystem function in different ecological contexts. Our results show that abundance, biomass and oxygen consumption of intertidal macrofauna and meiofauna are affected significantly by interactions among sediment particle size, beach slope and wave exposure. For macrofauna on less sloping beaches, the effect of these physical constraints is mediated by the local context, although for meiofauna and for macrofauna on intermediate and steeper beaches, the effects of physical constraints dominate. Steeper beach slopes, coarser particle sizes and increased wave exposure generally result in decreases in abundance, biomass and oxygen consumption, but these relationships are complex and non-linear. Sea-level rise is likely to lead to changes in ecosystem structure with generally negative impacts on ecosystem functions and ecosystem services. However, the impacts of sea-level rise will also be affected by local ecological context, especially for less sloping beaches.

  7. Real-space post-processing correction of thermal drift and piezoelectric actuator nonlinearities in scanning tunneling microscope images.

    Science.gov (United States)

    Yothers, Mitchell P; Browder, Aaron E; Bumm, Lloyd A

    2017-01-01

    We have developed a real-space method to correct distortion due to thermal drift and piezoelectric actuator nonlinearities on scanning tunneling microscope images using Matlab. The method uses the known structures typically present in high-resolution atomic and molecularly resolved images as an internal standard. Each image feature (atom or molecule) is first identified in the image. The locations of each feature's nearest neighbors are used to measure the local distortion at that location. The local distortion map across the image is simultaneously fit to our distortion model, which includes thermal drift in addition to piezoelectric actuator hysteresis and creep. The image coordinates of the features and image pixels are corrected using an inverse transform from the distortion model. We call this technique the thermal-drift, hysteresis, and creep transform. Performing the correction in real space allows defects, domain boundaries, and step edges to be excluded with a spatial mask. Additional real-space image analyses are now possible with these corrected images. Using graphite(0001) as a model system, we show lattice fitting to the corrected image, averaged unit cell images, and symmetry-averaged unit cell images. Statistical analysis of the distribution of the image features around their best-fit lattice sites measures the aggregate noise in the image, which can be expressed as feature confidence ellipsoids.

  8. Non-linear effects in the Snoek relaxation of Nb-O

    International Nuclear Information System (INIS)

    Hermida, E.B.; Povolo, F.

    1996-01-01

    Internal friction peaks measured as a function of temperature or frequency have been associated to non-linear processes only after studying how the amplitude of the applied stress affects the relaxation process. Here it is demonstrated that the partial derivative of the internal friction with respect to the frequency at constant temperature is a useful tool to determine that non-linear effects are involved. This analysis applied to actual data of the Snoek relaxation in Nb-O, reveals that at high interstitial contents non-linear effects appear. (orig.)

  9. THE TRANSFORMATIONAL PROCESSES INVOLVING MOTOR SKILLS THAT OCCUR UNDER THE INFLUENCE OF BASIC PRELIMINARY TRAINING IN YOUNG HANDBALL PLAYERS

    Directory of Open Access Journals (Sweden)

    Markovic Sasa

    2011-06-01

    Full Text Available The population from which we extracted a sample of 76 subjects consisted of elementary school students in Kursumlija, all male, aged 12-13, who were divided into a sub-sample consisting of 38 young handball players who took part in the training sessions of a school of handball and another sub-sample consisting of 38 non-athletes, who only took part in their regular physical education classes. The aim of the research was to determine the transformation processes involving motor skills, which occur under the influence of basic preliminary training in young handball players. The subject matter of the study was to examine whether a statistically significant increase in the level of motor skills would occur under the influence of physical exercise as part of basic preliminary training in the final as compared to the initial state. Six motor tests which define the dimensions of explosive and repetitive strength were used. The results of the research indicate that significant transformational processes involving the motor skills of young handball players occurred in the final as compared to the initial measuring, under the influence of basic preliminary training.

  10. TbPIF5 is a Trypanosoma brucei mitochondrial DNA helicase involved in processing of minicircle Okazaki fragments.

    Directory of Open Access Journals (Sweden)

    Beiyu Liu

    2009-09-01

    Full Text Available Trypanosoma brucei's mitochondrial genome, kinetoplast DNA (kDNA, is a giant network of catenated DNA rings. The network consists of a few thousand 1 kb minicircles and several dozen 23 kb maxicircles. Here we report that TbPIF5, one of T. brucei's six mitochondrial proteins related to Saccharomyces cerevisiae mitochondrial DNA helicase ScPIF1, is involved in minicircle lagging strand synthesis. Like its yeast homolog, TbPIF5 is a 5' to 3' DNA helicase. Together with other enzymes thought to be involved in Okazaki fragment processing, TbPIF5 localizes in vivo to the antipodal sites flanking the kDNA. Minicircles in wild type cells replicate unidirectionally as theta-structures and are unusual in that Okazaki fragments are not joined until after the progeny minicircles have segregated. We now report that overexpression of TbPIF5 causes premature removal of RNA primers and joining of Okazaki fragments on theta structures. Further elongation of the lagging strand is blocked, but the leading strand is completed and the minicircle progeny, one with a truncated H strand (ranging from 0.1 to 1 kb, are segregated. The minicircles with a truncated H strand electrophorese on an agarose gel as a smear. This replication defect is associated with kinetoplast shrinkage and eventual slowing of cell growth. We propose that TbPIF5 unwinds RNA primers after lagging strand synthesis, thus facilitating processing of Okazaki fragments.

  11. Collapse of nonlinear Langmuir waves

    International Nuclear Information System (INIS)

    Malkin, V.M.

    1986-01-01

    The dispersion of sufficiently intensive Langmuir waves is determined by intrinsic (electron) nonlinearity. During Langmuir collapse the wave energy density required for the appearance of electron nonlinearity is attained, generally speaking, prior to the development of dissipative processes. Up to now, the effect of electron nonlinearity on the collapse dynamics and spectrum of strong Langmuir turbulence ( which may be very appreciable ) has not been studied extensively because of the difficulty of describing nonlinear Langmuir waves. In the present paper the positive determinacy of the electron nonlinear hamiltonian is proven, the increment of modulation instability of a nonlinear Langmuir wave cluster localized in a cavity is calculated, and the universal law of their collapse is found

  12. Insular networks for emotional processing and social cognition: comparison of two case reports with either cortical or subcortical involvement.

    Science.gov (United States)

    Couto, Blas; Sedeño, Lucas; Sposato, Luciano A; Sigman, Mariano; Riccio, Patricia M; Salles, Alejo; Lopez, Vladimir; Schroeder, Johannes; Manes, Facundo; Ibanez, Agustin

    2013-05-01

    The processing of the emotion of disgust is attributed to the insular cortex (IC), which is also responsible for social emotions and higher-cognitive functions. We distinguish the role of the IC from its connections in regard to these functions through the assessment of emotions and social cognition in a double case report. These subjects were very rare cases that included a focal IC lesion and a subcortical focal stroke affecting the connections of the IC with frontotemporal areas. Both patients and a sample of 10 matched controls underwent neuropsychological and affective screening questionnaires, a battery of multimodal basic emotion recognition tests, an emotional inference disambiguation task using social contextual clues, an empathy task and a theory of mind task. The insular lesion (IL) patient showed no impairments in emotion recognition and social emotions and presented with a pattern of delayed reaction times (RTs) in a subset of both groups of tasks. The subcortical lesion (SL) patient was impaired in multimodal aversive emotion recognition, including disgust, and exhibited delayed RTs and a heterogeneous pattern of impairments in subtasks of empathy and in the contextual inference of emotions. Our results suggest that IC related networks, and not the IC itself, are related to negative emotional processing and social emotions. We discuss these results with respect to theoretical approaches of insular involvement in emotional and social processing and propose that IC connectivity with frontotemporal and subcortical regions might be relevant for contextual emotional processing and social cognition. Copyright © 2012 Elsevier Ltd. All rights reserved.

  13. FMRI evidence for the involvement of the procedural memory system in morphological processing of a second language.

    Directory of Open Access Journals (Sweden)

    Christos Pliatsikas

    Full Text Available Behavioural evidence suggests that English regular past tense forms are automatically decomposed into their stem and affix (played  = play+ed based on an implicit linguistic rule, which does not apply to the idiosyncratically formed irregular forms (kept. Additionally, regular, but not irregular inflections, are thought to be processed through the procedural memory system (left inferior frontal gyrus, basal ganglia, cerebellum. It has been suggested that this distinction does not to apply to second language (L2 learners of English; however, this has not been tested at the brain level. This fMRI study used a masked-priming task with regular and irregular prime-target pairs (played-play/kept-keep to investigate morphological processing in native and highly proficient late L2 English speakers. No between-groups differences were revealed. Compared to irregular pairs, regular pairs activated the pars opercularis, bilateral caudate nucleus and the right cerebellum, which are part of the procedural memory network and have been connected with the processing of morphologically complex forms. Our study is the first to provide evidence for native-like involvement of the procedural memory system in processing of regular past tense by late L2 learners of English.

  14. The Effects of Argument Quality and Involvement Type on Attitude Formation and Attitude Change: A Test of Dual-Process and Social Judgment Predictions

    Science.gov (United States)

    Park, Hee Sun; Levine, Timothy R.; Kingsley Westerman, Catherine Y.; Orfgen, Tierney; Foregger, Sarah

    2007-01-01

    Involvement has long been theoretically specified as a crucial factor determining the persuasive impact of messages. In social judgment theory, ego-involvement makes people more resistant to persuasion, whereas in dual-process models, high-involvement people are susceptible to persuasion when argument quality is high. It is argued that these…

  15. FOREWORD: International Topical Workshop on Plasma Physics: Coherent Processes in Nonlinear Media. Sponsored by the ICTP (Trieste) and the European Union (Brussels)

    Science.gov (United States)

    Shukla, P. K.; Bingham, R.; Stenflo, L.; Dawson, J. M.

    1996-01-01

    Starting in 1989 we have created a forum at the International Centre for Theoretical Physics, Trieste, where scientists from different parts of the world can meet and exchange information in the frontier areas of physics. In the three previous meetings, we focused on large amplitude waves and fields in plasmas, the physics of dusty plasmas, and wave-particle interactions and energization in plasmas. In 1995, we came up with a fresh idea of organizing somewhat enlarged but still well focused research topics that are cross-disciplinary. Thus, the usual 'fourth-week activity' of the Plasma Physics College at the ICTP was replaced by an International Topical Workshop on Plasma Physics: Coherent Processes in Nonlinear Media, which was held at the ICTP during the period 16-20 October, 1995. This provided us an opportunity to draw eminent speakers from many closely related fields such as plasma physics, fluid dynamics, nonlinear optics, and astrophysics. The Workshop was attended by 82 delegates from 34 countries, and the participation from the industrial and the developing countries was about half each. The programme included 4 review and 29 topical invited lectures. In addition, about 30 contributed papers were presented as posters in two sessions. The latter were created in order to give opportunities to younger physicists for displaying the results of their recent work and to obtain constructive comments from the other participants. During the five days at the ICTP, we focused on almost all the various aspects of nonlinear phenomena that are common in different branches of science. The review and topical lectures as well as the posters dealt with the most recent advances in coherent nonlinear processes in space and astrophysical plasmas, in fluids and optics, in low temperature dusty plasmas, as well as in laser produced and magnetically confined laboratory plasmas. The focus was on the physics of various types of waves and their generation mechanisms, the development

  16. The Orosomucoid 1 protein is involved in the vitamin D – mediated macrophage de-activation process

    Energy Technology Data Exchange (ETDEWEB)

    Gemelli, Claudia, E-mail: claudia.gemelli@unimore.it [Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 287, 41125 Modena (Italy); Center for Regenerative Medicine, University of Modena and Reggio Emilia, Via Gottardi 100, 41125 Modena (Italy); Martello, Andrea; Montanari, Monica; Zanocco Marani, Tommaso; Salsi, Valentina; Zappavigna, Vincenzo; Parenti, Sandra; Vignudelli, Tatiana; Selmi, Tommaso; Ferrari, Sergio; Grande, Alexis [Department of Life Sciences, University of Modena and Reggio Emilia, Via Campi 287, 41125 Modena (Italy)

    2013-12-10

    Orosomucoid 1 (ORM1), also named Alpha 1 acid glycoprotein A (AGP-A), is an abundant plasma protein characterized by anti-inflammatory and immune-modulating properties. The present study was designed to identify a possible correlation between ORM1 and Vitamin D3 (1,25(OH)2D3), a hormone exerting a widespread effect on cell proliferation, differentiation and regulation of the immune system. In particular, the data described here indicated that ORM1 is a 1,25(OH)2D3 primary response gene, characterized by the presence of a VDRE element inside the 1 kb sequence of its proximal promoter region. This finding was demonstrated with gene expression studies, Chromatin Immunoprecipitation and luciferase transactivation experiments and confirmed by VDR full length and dominant negative over-expression. In addition, several experiments carried out in human normal monocytes demonstrated that the 1,25(OH)2D3 – VDR – ORM1 pathway plays a functional role inside the macrophage de-activation process and that ORM1 may be considered as a signaling molecule involved in the maintenance of tissue homeostasis and remodeling. - Highlights: • ORM1 is a Vitamin D primary response gene. • VD and its receptor VDR are involved in the de-activation process mediated by human resident macrophages. • The signaling pathway VD-VDR-ORM1 plays an important role in the control of macrophage de-activation process. • ORM1 may be defined as a signaling molecule implicated in the maintenance of tissue homeostasis and remodeling.

  17. The Orosomucoid 1 protein is involved in the vitamin D – mediated macrophage de-activation process

    International Nuclear Information System (INIS)

    Gemelli, Claudia; Martello, Andrea; Montanari, Monica; Zanocco Marani, Tommaso; Salsi, Valentina; Zappavigna, Vincenzo; Parenti, Sandra; Vignudelli, Tatiana; Selmi, Tommaso; Ferrari, Sergio; Grande, Alexis

    2013-01-01

    Orosomucoid 1 (ORM1), also named Alpha 1 acid glycoprotein A (AGP-A), is an abundant plasma protein characterized by anti-inflammatory and immune-modulating properties. The present study was designed to identify a possible correlation between ORM1 and Vitamin D3 (1,25(OH)2D3), a hormone exerting a widespread effect on cell proliferation, differentiation and regulation of the immune system. In particular, the data described here indicated that ORM1 is a 1,25(OH)2D3 primary response gene, characterized by the presence of a VDRE element inside the 1 kb sequence of its proximal promoter region. This finding was demonstrated with gene expression studies, Chromatin Immunoprecipitation and luciferase transactivation experiments and confirmed by VDR full length and dominant negative over-expression. In addition, several experiments carried out in human normal monocytes demonstrated that the 1,25(OH)2D3 – VDR – ORM1 pathway plays a functional role inside the macrophage de-activation process and that ORM1 may be considered as a signaling molecule involved in the maintenance of tissue homeostasis and remodeling. - Highlights: • ORM1 is a Vitamin D primary response gene. • VD and its receptor VDR are involved in the de-activation process mediated by human resident macrophages. • The signaling pathway VD-VDR-ORM1 plays an important role in the control of macrophage de-activation process. • ORM1 may be defined as a signaling molecule implicated in the maintenance of tissue homeostasis and remodeling

  18. The right look for the job: decoding cognitive processes involved in the task from spatial eye-movement patterns.

    Science.gov (United States)

    Król, Magdalena Ewa; Król, Michał

    2018-02-20

    The aim of the study was not only to demonstrate whether eye-movement-based task decoding was possible but also to investigate whether eye-movement patterns can be used to identify cognitive processes behind the tasks. We compared eye-movement patterns elicited under different task conditions, with tasks differing systematically with regard to the types of cognitive processes involved in solving them. We used four tasks, differing along two dimensions: spatial (global vs. local) processing (Navon, Cognit Psychol, 9(3):353-383 1977) and semantic (deep vs. shallow) processing (Craik and Lockhart, J Verbal Learn Verbal Behav, 11(6):671-684 1972). We used eye-movement patterns obtained from two time periods: fixation cross preceding the target stimulus and the target stimulus. We found significant effects of both spatial and semantic processing, but in case of the latter, the effect might be an artefact of insufficient task control. We found above chance task classification accuracy for both time periods: 51.4% for the period of stimulus presentation and 34.8% for the period of fixation cross presentation. Therefore, we show that task can be to some extent decoded from the preparatory eye-movements before the stimulus is displayed. This suggests that anticipatory eye-movements reflect the visual scanning strategy employed for the task at hand. Finally, this study also demonstrates that decoding is possible even from very scant eye-movement data similar to Coco and Keller, J Vis 14(3):11-11 (2014). This means that task decoding is not limited to tasks that naturally take longer to perform and yield multi-second eye-movement recordings.

  19. The problem of the involvement of the off-balance reserves of the metallic ores into the production process

    Directory of Open Access Journals (Sweden)

    V. I. Golik

    2017-12-01

    Full Text Available The underground mining of the ore deposits by means of the intensive methods of the traditional technologies is characterized by the loss of the reserves, which are off-balance for the technologies applied. The experience, which was accumulated by the state-of-the-art enterprises before the economic reforms and the crisis indicates, that it is possible to decrease the loss of metals. This can be assumed by means of involving the off-balance reserves into the production process with the metal lixiviation during closed work. The purpose of the present-day research is the substantiation of the technical possibility and economic reasonability of the lixiviation of metals from the off-balance reserves and poorly balance ores. The correct estimation of the perspectives of those combined technology is still one of the purposes. It is a matter of fact that combining traditional technologies of the underground mining with new ones concerned with the creation of the effective lixiviation of metals from ores can be carried out with the two-stage processing. It happens when the excavation of some amount of the balance reserves creates the compensational space for crushing off-balance reserves. Involving off-balance ores into the production process solves a set of the mining production problems. For example, the fullness of mineral resources usage, the strengthening of the resource base, the reduction of load of the environment and the security of works. The involvement of the off-balance reserves into the development in the course of the revaluation of the resources and in the technological facilities of the development in the context of the growth of the scale of production reduces the production price to the competitive level. The field of application of these results is in the mining enterprises which extract solid metal-containing ores by means of the underground mining. These ores are mostly of the nonferrous, rare and precious metals, which are easily

  20. Non-linear effects of initial melt temperatures on microstructures and mechanical properties during quenching process of liquid Cu{sub 46}Zr{sub 54} alloy

    Energy Technology Data Exchange (ETDEWEB)

    Mo, Yun-Fei [School of Physics and Microelectronics Science, Hunan University, Changsha, 410082 (China); Liu, Rang-Su, E-mail: liurangsu@sina.com [School of Physics and Microelectronics Science, Hunan University, Changsha, 410082 (China); Tian, Ze-An; Liang, Yong-Chao [School of Physics and Microelectronics Science, Hunan University, Changsha, 410082 (China); Zhang, Hai-Tao [School of Physics and Microelectronics Science, Hunan University, Changsha, 410082 (China); Department of Electronic and Communication Engineering, Changsha University, Changsha 410003 (China); Hou, Zhao-Yang [Department of Applied Physics, Chang’an University, Xi’an 710064 (China); Liu, Hai-Rong [College of Materials Science and Engineering, Hunan University, Changsha 410082 (China); Zhang, Ai-long [College of Physics and Electronics, Hunan University of Arts and Science, Changde 415000 (China); Zhou, Li-Li [Department of Information Engineering, Gannan Medical University, Ganzhou 341000 (China); Peng, Ping [College of Materials Science and Engineering, Hunan University, Changsha 410082 (China); Xie, Zhong [School of Physics and Microelectronics Science, Hunan University, Changsha, 410082 (China)

    2015-05-15

    A MD simulation of liquid Cu{sub 46}Zr{sub 54} alloys has been performed for understanding the effects of initial melt temperatures on the microstructural evolution and mechanical properties during quenching process. By using several microstructural analyzing methods, it is found that the icosahedral and defective icosahedral clusters play a key role in the microstructure transition. All the final solidification structures obtained at different initial melt temperatures are of amorphous structures, and their structural and mechanical properties are non-linearly related to the initial melt temperatures, and fluctuated in a certain range. Especially, there exists a best initial melt temperature, from which the glass configuration possesses the highest packing density, the optimal elastic constants, and the smaller extent of structural softening under deforming.