AquaBuOY

DEFF Research Database (Denmark)

Weinstein, Alla; Fredrikson, Göran; Claeson, Lennart

2003-01-01

BuOY in five representative generic sea states. Ocean energy and offshore wave energy conversion in the United States is at a significant milestone. During the next year, ocean energy technology developers and energy officials have the potential to deploy pilot scale ocean power plants and transition......This paper describes development of the mathematical model simulating ocean performance of an offshore wave energy point absorber device-AquaBuOY. The AquaBuOY is the next generation of the technology, based on the IPS point absorber system and the hose pump, both of Sweden. AquaEnergy Group Ltd......, engineers, and developers can continue to lay the groundwork for government spending and interest in ocean energies....

Solvation of UCl{sub 6}{sup 2-} anionic complex by MeBu{sub 3}N{sup +}, BuMe{sub 2}Im{sup +} and BuMeIm{sup +} cations

Energy Technology Data Exchange (ETDEWEB)

Bosse, Emilie; Den Auwer, Christophe; Berthon, Claude; Guilbaud, Philippe; Moisy, Philippe [CEA Marcoule, DRCP/SCPS, BP 17171, 30207 Bagnols sur Ceze Cedex (France); Grigoriev, Mikhail S. [A.N. Frumkin Institute of Physical Chemistry and Electrochemistry, RAS, Leninskii Prosp. 31, 119991 Moscow (Russian Federation); Nikitenko, Serguei [CNAB, UMR 5084, CNRS - Universite de Bordeaux 1, BP 120 Le Haut Vigneau, 33175 Gradignan Cedex (France); Le Naour, Claire; Cannes, Celine [IPN, UMR 8608, CNRS, Universite Paris-Sud, 91406 Orsay (France)

2008-07-01

The complexes [MeBu{sub 3}N]{sub 2}[UCl{sub 6}] and [BuMe{sub 2}Im]{sub 2}[UCl{sub 6}] were characterized in the solid state and in solution of [MeBu{sub 3}N][Tf{sub 2}N], [BuMe{sub 2}Im][Tf{sub 2}N] and [BuMeIm][Tf{sub 2}N] room temperature ionic liquids using single-crystal XRD, EXAFS, electrochemistry, UV-visible absorption spectroscopy and NMR. In the solid and in solution, the existence of hydrogen bonding between the anionic UCl{sub 6}{sup 2-} complex and the ionic liquid cations were revealed by these techniques. The MeBu{sub 3}N{sup +} cation interacts with UCl{sub 6}{sup 2-} via the protons on the alpha carbon atoms of nitrogen. The protons of the imidazolium ring account for the interaction between the BuMe{sub 2}Im+ cation and the UCl{sub 6}{sup 2-} anion. For the BuMeIm{sup +} cation the major interaction was confirmed between the most acidic proton on C(2) and UCl{sub 6}{sup 2-}. The experimental results also show that the intensity of the interaction between the UCl{sub 6}{sup 2-} anion and the cation varies with the ionic liquid cation in the following order: MeBu{sub 3}N{sup +} {approx} BuMe{sub 2}Im{sup +} << BuMeIm{sup +}. (authors)

I.Kanta idejas un to ietekme uz mūsdienu tiesību attīstību

OpenAIRE

Smiltēna, Anda

2007-01-01

Darbs ir veltīts Imanuela Kanta tiesību filozofijas analīzei, uzmanību pievēršot tiesību teorijas jautājumiem, kā arī šo ideju praktiskajai ietekmei mūsdienu tiesību zinātnē. Pirmajā nodaļā aprakstītas galvenās Kanta tiesību filozofijas idejas, kas veido tiesību teorijas bāzi, nosaka tiesību sistēmu un to veidojošo elementu īpašības, nodala tiesības no morāles, iezīmē kategoriskā imperatīva un brīvības kategorijas nozīmi tiesībās. Otrā nodaļa veltīta neokantisma kustībai tiesībās un tās galve...

Albino Farelerde Bisfenol A Tarafından Teşvik Edilen Genotoksisiteye Karşı Yeşil Kahvenin Koruyucu Rolünün Araştırılması

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Burhan İŞTAR

2016-09-01

Full Text Available Özet. Bu çalışmada gıda ve içecek ambalajlama materyallerinde sıkça kullanılan kimyasal maddelerden biri olan Bisfenol A (BFA’nın Swiss albino farelerde muhtemel fizyolojik ve genotoksik etkileri ile bu etkilere karşı yeşil kahvenin koruyucu rolü araştırılmıştır. Fizyolojik etkiler; canlı ağırlık ve karaciğer-böbrek organ ağırlıklarının ölçümü ile genotoksik etkiler ise; eritrosit ve yanak mukoza epitelyum hücrelerindeki mikronukleus (MN sıklığının, kemik iliği hücrelerinde ise kromozomal hasar oluşumunun tespitiyle değerlendirilmiştir. Fareler her grupta altı (6 hayvan olacak şekilde toplam altı (6 gruba ayrılmış, kontrol grubundaki fareler çeşme suyu, uygulama grubundaki fareler ise yeşil kahvenin 100 mg/kg c.a ve 400 mg/kg c.a dozlarıyla ve BFA’nın 50 mg/kg c.a dozuyla beslenmişlerdir. Sonuçta BFA uygulaması canlı ağırlıklarda ve organ ağırlıklarında istatistiksel açıdan önemli bir azalmaya neden olurken, MN ve kromozomal anormallik sıklığında ise önemli bir artışa neden olmuştur. Yeşil kahve uygulaması ise BFA’nın söz konusu olumsuz etkilerini iyileştirerek, tüm parametrelerde doza bağlı bir iyileşme göstermiştir. BFA’nın belli bir doz eşiğinden sonra toksisiteye sebep olduğu, yeşil kahvenin ise bu toksisiteyi azaltmada etkili bir antioksidant ürün olduğu anlaşılmıştır.Anahtar Kelimeler: Bisfenol A, Fizyoloji, Genotoksisite, Kromozomal Anormallikler, Mikronukleus, Yeşil Kahve Abstract. This study researches into the potential physiologic and genotoxic effects of Bisphenol A, which is one of the most frequent chemical substance used in food and beverage packaging materials, on Swiss Albino mice and the protective role of green coffee against these effects. The study analyzes the physiologic effects by measuring the live weight, liver and kidney weight, whilst determining the genotoxic effects by frequency of micronucles (MN on

A cationic Agi( PNPtBu) species acting as PNP transfer agent: facile synthesis of Pd(PNPtBu)(alkyl) complexes and their reactivity compared to PCPtBu analogues

NARCIS (Netherlands)

Vlugt, van der J.I.; Siegler, M.A.; Janssen, M.C.C.; Vogt, D.; Spek, A.L.

2009-01-01

The straightforward synthesis of cationic complex 1, [Ag(PNPtBu)]BF4 (PNPtBu = 1,2-bis[(di-tert-butylphosphino)methyl]pyridine), and its facile transmetalating properties toward gold and palladium are described. The corresponding Au complex [Au(PNPtBu)]2(BF4)2 (2) exists as a dimer in the solid

AHMEDİYE FLOATING ISLAND AHMEDİYE YÜZENADASI

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Pınar TAŞKIRAN (M.A.H.

2006-09-01

ının inceleme konusu olmuştur. Söz konusu oluşum, başta coğrafya olmak üzere biyoloji, jeoloji ve çevre bilimlerinin de inceleme alanına girmektedir. Ancak yüzenada terimi Coğrafya ilmi sayesinde literatüre girmişve adaların oluşumu, tanımı ve tanıtımı üzerine ilk çalışmalar yine coğrafyacılar tarafından yapılmıştır. Bu konuda Prof. Dr. İhsan BULUT’ un önemli çalışmalarıbulunmaktadır. Yüzenadalar çok çeşitli özellikleri ile bilim dünyasının dikkatini çekmektedir. Başta zengin flora ve faunasıyla içerisinde bulunduğu ortamdan belirgin bir şekilde ayrılmaktadır. Bu adalar, göl alanı içerisinde gelişmeleri dolayısıyla,insanların hep dikkatini çeken sulak alanlar durumundadır. Doğal ve beşerî faktörlerle ekosistemde meydana gelen bozulmaların en bariz olarak gözlenebildiği kesimler yine bu sulak alanlardır. İnorganik ve organik minerallerin uygun iklim koşulları altında optimum karışımı yine sulak alanlarda gerçekleşirken, inorganik minerallerde bulunan fosfat ve serbest atmosferden sağlanan nitratla gür ve türce zengin sulak alan bitkileri yetişmektedir. Yüzenadalar hemen her iklim kuşağında görülmesine rağmen yine de dünyamızın bu oluşumlar bakımından fakir olduğu söylenebilir. Ancak bu durum, şüphesiz bu alandaki çalışmaların yetersiz olmasının bir sonucudur. Kendine özgü doğal ortamıyla çevresinden ayrılan ve göl alanında yüzer halde her yöne kolayca hareket edebilen yüzenadalar, çevrelerinin adeta bir sembolü rolünü üstlenirken, bölge insanını kendisine çeken görsel doğal bir turistik cazibe merkezi olma özelliğini de taşırlar. Ülkemizde kayıtlara geçen yüzenada bulunan il sayısı 8’dir. Ancak ülkemizin farklı kesimlerinde büyüklü küçüklü çok sayıda sulak alan bulunmaktadır. Dolayısıyla da araştırmalar arttıkça farklı kesimlerde yüzenadalarla karşılaşılacaktır. İşte bilinenlere ilave edebileceğimiz bir �

PC-3 Prostat Kanser Hücreleri Üzerinde İndosyanin Yeşili Kullanarak Yapılan Fotodinamik Terapinin AO/PI Boyama Testi Sonuçları

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Mustafa Kemal RUHİ

2017-06-01

Full Text Available Fotodinamik terapi (FDT prostat kanseri tedavisinde henüz araştırma aşamasında olan sağaltıcı bir alternatiftir. FDT, ışığa duyarlı bir kimyasal maddenin (fotosensitizan ışık ile aktive edilmesi ve aktive olan kimyasalın kanserli bölgedeki hücre canlılığını baskılayıcı etkiye neden olması prensibine dayanmaktadır. Bu yeni tedavi yöntemi hem seçiciliği hem de yan etkilerinin azlığı nedeniyle alternatifler arasında ön plana çıkmaktadır. FDT’de kullanılan fotosensitizanın ışıksız ortamda sitotoksik olmaması ve vücuttan kolay atılabilmesi istenmektedir. Ayrıca herhangi bir fotosensitizanın yakın kızılaltı ışık ile aktive olması, bu dalgaboyunun deriye ve diğer dokulara daha fazla nüfuz etmesinden dolayı tercih sebebidir. Bu özelliklere sahip olan İndosiyanin Yeşili (ISY daha çok floresans özelliği ile ön plana çıkmış ve görüntüleme amaçlı olarak kullanılmıştır. Bu in vitro çalışmada ISY-FDT’nin farklı inkübasyon süreleri sonundaki etkisi AO/PI boyama yöntemi kullanarak ortaya konmuştur. Elde edilen sonuçlar ISY-FDT’nin hücre canlılığını baskıladığını göstermektedir.

A cationic Ag-I(PNPtBu) species acting as PNP transfer agent: Facile synthesis of Pd(PNPtBu)(alkyl) complexes and their reactivity compared to PCPtBu analogues

NARCIS (Netherlands)

van der Vlugt, J.I.; Siegler, M.A.; Janssen, M.; Vogt, D.; Spek, A.L.

2009-01-01

The straightforward Synthesis of cationic complex 1, [Ag(PNtBu)]BF4 (PNPtBu = 1,2-bis[(di-tert-butylphosphino)methyl]pyridine), and its facile transmetalating properties toward gold and palladium are described. The corresponding Au complex [Au(PNPtBu)](2)(BF4)(2) (2) exists its a dimer in the solid

El Nino and ground/underground water decreasing effects on coffee cultivation in DakNong Province, Vietnam by using GIS.

Science.gov (United States)

Duong, Anh Quan; Quy Bui, Ngoc; Luu, The Anh; Kainz, Wolfgang

2014-05-01

El Nino is one of most common climatic events which are widely spread over the world. In case of Vietnam, the El Nino or ENSO event has various effects on agricultural cultivation over whole country; in the Central Highlands area, the coffee cultivation also has been affected heavily. The coffee is one of most important products of this area. Our study area, the Dak Nong province located in the Central Highlands, the mountainous and highlands in central of Vietnam. The coffee production contributes roughly 40% of total GDP of the province. This province climate is influenced by tropical monsoon and high altitude terrain. The area has two seasons in which dry season from November to end of March and the wet season cover the rest. There is 80-90% of precipitation concentrated in wet season. In El Nino years, the dry season is longer and drier than normal which affects the agricultural cultivation especially coffee. The effects of El Nino phenomenon on coffee cultivation need to clarify in order to help farmers and decision makers making their solutions. The ground/underground water has been decreased by over watering of coffee growers as well as deforestation making water shortage in dry season. The over watering of coffee cultivation wasted more than 80% water resources especially underground water use. In years of 1997-1998, coffee productivity decreased 30%; in years of 2003, the coffee productivity was downed by 25%; both examples show the relation between the combination of ENSO and decreasing of Ground/underground water and the coffee production in Dak Nong province. This is a necessary research to evaluate the effects of the combination. This paper using GIS tools to estimate the effects of El Nino phenomenon combined with ground/underground water and the coffee cultivation in Dak Nong province

Synthesis and structure of the extended phosphazane ligand [(1,4-C6H4){N(μ-PN(t)Bu)2N(t)Bu}2](4).

Science.gov (United States)

Sevilla, Raquel; Less, Robert J; García-Rodríguez, Raúl; Bond, Andrew D; Wright, Dominic S

2016-02-07

The reaction of the phenylene-bridged precursor (1,4-C6H4)[N(PCl2)2]2 with (t)BuNH2 in the presence of Et3N gives the new ligand precursor (1,4-C6H4)[N(μ-N(t)Bu)2(PNH(t)Bu)2]2, deprotonation of which with Bu2Mg gives the novel tetraanion [(1,4-C6H4){N(μ-N(t)Bu)2(PN(t)Bu)2}2](4-).

Analysis of poultry eating and drinking behavior by software eYeNamic

Directory of Open Access Journals (Sweden)

A. De Montis

2013-09-01

Full Text Available Constant presence of at least one operator in livestock buildings for broilers would allow a perfect control of animal behaviour and, especially, deviations in feeding and drinking patterns, in the perspective of a high welfare status. However, as nowadays it is impossible for a farmer to be present in the farm all day long, automatic monitoring systems are required. The purpose of this paper is to introduce a system (eYeNamic for automatic monitoring and analyzing broilers’ behavior in a farm. eYeNamic is a camera system introduced and produced by Fancom BV, a company operating in the field of automation of livestock facilities. It includes three cameras located on the ridge of the broiler house and able to monitor chickens’ behaviour twenty-four hours a day. Through eYeNamic it is possible to process the images and to obtain a measure of animals’ distribution and activity, which can be conceived as valuable indicators of animal welfare. The study presented in this paper was divided into several phases: data collection, images visualization, observation of the distribution and activity of the chickens, and statistical analysis of the observations. The analysis of correlation between the number of 14 days old broilers near the feeding line (manual counted and the average occupation density measured with eYenamic indicates that the best conditions have occurred with a 50 cm by 75 cm area around each feeding pan. With reference to the drinking line, the best response was found in an area 50 cm wide and the whole drinking line long. For the activity behavior, there was no significant correlation between activity and number of chickens eating from all the pans: this confirms that broilers while eating reduce their activity. It was concluded from this study that eYeNamic is a good system to observe animal behavior and, especially, to take care of their drinking and eating behaviour. A satisfactory correspondence between eYeNamic remote and

Antifungal activity of rimocidin and a new rimocidin derivative BU16 produced by Streptomyces mauvecolor BU16 and their effects on pepper anthracnose.

Science.gov (United States)

Jeon, B J; Kim, J D; Han, J W; Kim, B S

2016-05-01

The objective of this study was to explore antifungal metabolites targeting fungal cell envelope and to evaluate the control efficacy against anthracnose development in pepper plants. A natural product library comprising 3000 microbial culture extracts was screened via an adenylate kinase (AK)-based cell lysis assay to detect antifungal metabolites targeting the cell envelope of plant-pathogenic fungi. The culture extract of Streptomyces mauvecolor strain BU16 displayed potent AK-releasing activity. Rimocidin and a new rimocidin derivative, BU16, were identified from the extract as active constituents. BU16 is a tetraene macrolide containing a six-membered hemiketal ring with an ethyl group side chain instead of the propyl group in rimocidin. Rimocidin and BU16 showed broad-spectrum antifungal activity against various plant-pathogenic fungi and demonstrated potent control efficacy against anthracnose development in pepper plants. Antifungal metabolites produced by S. mauvecolor strain BU16 were identified to be rimocidin and BU16. The compounds displayed potent control efficacy against pepper anthracnose. Rimocidin and BU16 would be active ingredients of disease control agents disrupting cell envelope of plant-pathogenic fungi. The structure and antifungal activity of rimocidin derivative BU16 is first described in this study. © 2016 The Society for Applied Microbiology.

İSTANBUL’DA YER ALAN YEŞİL RESTORAN İŞLETMELERİ HİZMET KALİTESİNİN GRSERV MODELİ İLE DEĞERLENDİRİLMESİ

OpenAIRE

Kurnaz, Alper; Özdoğan, Osman Nuri

2017-01-01

İnsanların çevreye ve sağlıklı ürüne olanilgileri sürekli artmaktadır. Bu artış ile birlikte dışarıda yeme içme ihtiyacısonucu yiyecek içecek işletmelerinde sunulan hizmetin kalitesi önemkazanmaktadır. Yeşil restoranların sürdürülebilir ürünler kullanması ve çevreyeduyarlı hizmetleri tercih etmesi müşteriler tarafından talep edilenuygulamalardır. Bu bağlamda yeşil restoranların sunmuş olduğu hizmetin niteliğive bunun ölçülmesi ihtiyaç haline gelmiştir. Bu ihtiyaç hizmet kalitesikavramını ön p...

Bu-2470, a new peptide antibiotic complex. II. Structure determination of Bu-2470 A, B1, B2a and B2b.

Science.gov (United States)

Sugawara, K; Yonemoto, T; Konishi, M; Matsumoto, K; Miyaki, T; Kawaguchi, H

1983-06-01

The structures of Bu-2470 A, B1, B2a, and B2b have been determined. Bu-2470 A is a simple octapeptide having no fatty acid moiety, while Bu-2470 B1, B2a and B2b are octapeptides that have been acylated with a beta-hydroxy C11 or C10 fatty acid. The octapeptide structure of Bu-2470 components was found identical with that of octapeptin C1, hence generic names of octapeptin C0, C2, C3 and C4 are proposed for Bu-2470 A, B1, B2a and B2b, respectively.

Lowering the YE+1 end-cap for CMS

CERN Multimedia

Maximilien Brice

2007-01-01

On 9 January 2007, the massive YE+1 end-cap was lowered into the CMS cavern. This is a very precise process as the crane must lower the end-cap through minimal clearance without tilt or sway. Once in the cavern, the end-cap is then positioned over the end of the barrel to detect particles produced in collisions that travel close to the axis of the beams.

New superhindered polydentate polyphosphine ligands P(CH2CH2P(t)Bu2)3, PhP(CH2CH2P(t)Bu2)2, P(CH2CH2CH2P(t)Bu2)3, and their ruthenium(II) chloride complexes.

Science.gov (United States)

Gilbert-Wilson, Ryan; Field, Leslie D; Bhadbhade, Mohan M

2012-03-05

The synthesis and characterization of the extremely hindered phosphine ligands, P(CH(2)CH(2)P(t)Bu(2))(3) (P(2)P(3)(tBu), 1), PhP(CH(2)CH(2)P(t)Bu(2))(2) (PhP(2)P(2)(tBu), 2), and P(CH(2)CH(2)CH(2)P(t)Bu(2))(3) (P(3)P(3)(tBu), 3) are reported, along with the synthesis and characterization of ruthenium chloro complexes RuCl(2)(P(2)P(3)(tBu)) (4), RuCl(2)(PhP(2)P(2)(tBu)) (5), and RuCl(2)(P(3)P(3)(tBu)) (6). The bulky P(2)P(3)(tBu) (1) and P(3)P(3)(tBu) (3) ligands are the most sterically encumbered PP(3)-type ligands so far synthesized, and in all cases, only three phosphorus donors are able to bind to the metal center. Complexes RuCl(2)(PhP(2)P(2)(tBu)) (5) and RuCl(2)(P(3)P(3)(tBu)) (6) were characterized by crystallography. Low temperature solution and solid state (31)P{(1)H} NMR were used to demonstrate that the structure of RuCl(2)(P(2)P(3)(tBu)) (4) is probably analogous to that of RuCl(2)(PhP(2)P(2)(tBu)) (5) which had been structurally characterized.

N1'-fluoroethyl-naltrindole (BU97001) and N1'-fluoroethyl-(14-formylamino)-naltrindole (BU97018) potential δ-opioid receptor PET ligands

International Nuclear Information System (INIS)

Tyacke, Robin J.; Robinson, Emma S.J.; Schnabel, Rebecca; Lewis, John W.; Husbands, Stephen M.; Nutt, David J.; Hudson, Alan L.

2002-01-01

The properties of two prospective positron emission tomography (PET) ligands for the δ-opioid receptor, N1'-fluoroethyl-naltrindole (BU97001) and N1'-fluoroethyl-(14-formylamino)-naltrindole (BU97018) were investigated. Both were antagonists in the mouse vas deferens, and showed high affinity and selectivity, 1.81 nM and 3.09 nM respectively. [ 3 H]BU97001 binding to rat whole brain was also of high affinity, K D of 0.42 nM of and B MAX of 59.95 fmol mg of protein -1 . In autoradiographic studies, it was found to bind to brain areas previously shown to be associated with the δ-opioid receptor and good correlations were found to exist with naltrindole and DPDPE. BU97018 and especially BU97001 appear to show good potential as δ-opioid receptor PET ligands with the incorporation of 18 F

Lowering of the YE+2 end-cap for CMS

CERN Multimedia

Maximilien Brice

2006-01-01

Lowering of the second end-cap disk of CMS, designated YE+2, took place on 12 December 2006. The huge disk, 15 m high and weighing around 900 tonnes, is equipped on both sides with muon detectors. The lowering operation started at around 7am and finished about 10 hours later with the arrival of the disk into the cavern 100 m below the surface hall.

Pagaidu aizsardzība pret vardarbību civilprocesā.

OpenAIRE

Krauze, Kintija

2018-01-01

anotācija Maģistra darbā „Pagaidu aizsardzības pret vardarbību Civilprocesā” autore izpēta pagaidu aizsardzības pret vardarbību regulējuma ieviešanas praksi Latvijas tiesību sistēmā, aplūkojot un salīdzinot to ar citu valstu pieredzi regulējuma ieviešanā. Tika aplūkots pastāvošais pagaidu aizsardzības pret vardarbību regulējuma nepilnības. Pētījuma mērķis ir noskaidrot, vai Latvijas pagaidu aizsardzības pret vardarbību regulējums ir efektīvākais veids, kā aizsargāt personas no vardarbības. ...

Synthesis and X-ray structures of dilithium complexes of the phosphonate anions [PhP(E)(N(t)Bu)(2)](2-) (E = O, S, Se, Te) and dimethylaluminum derivatives of [PhP(E)(N(t)Bu)(NH(t)Bu)](-) (E = S, Se).

Science.gov (United States)

Briand, Glen G; Chivers, Tristram; Krahn, Mark; Parvez, Masood

2002-12-16

The dilithium salts of the phosphonate dianions [PhP(E)(N(t)Bu)(2)](2-) (E = O, S, Se) are generated by the lithiation of [PhP(E)(NH(t)Bu)(2)] with n-butyllithium. The formation of the corresponding telluride (E = Te) is achieved by oxidation of [Li(2)[PhP(N(t)Bu)(2)

Yeşilçam Döneminde Van’ın Sinema Kültürü Van’s Cinema Culture in Yeşilçam Period

Directory of Open Access Journals (Sweden)

Arzu ERTAYLAN

2013-09-01

aim, importance and scope of the work is defined as well as the limitations and problems faced during the research. In the second part of the work, the advantages and disadvantages of the concepts, ‘descriptive analysis method’ and ‘unstructured interview technique’ that this research is based on are explained. The latter part deals with the cinema culture of Van till 1980s with the help of the topics that are defined. As a conclusion, the data gathered during the reserach is evaluated under the light of the knowledge on Turkish cinema in relation to the social and political situation of Turkey. İletişim ve güzel sanatlar fakültelerinin sayılarındaki artışa bağlı olarak sinema konusunda yapılan teorik çalışmaların sayıca arttığı yadsınamaz bir gerçek haline gelmiştir. Türk sinemasının geçmişi ve bugünü pek çok akademisyen ve sinemasever tarafından mercek altına alınmış, yeni ve eski çok sayıda film, konuları, üslupları, ideolojileri, türleri, yönetmenleri ve filmlerdeki herhangi spesifik bir konunun temsili gibi pek çok açıdan incelenmiş, filmler belli araştırma yöntemlerine dayanarak analiz edilmiş ve sonuçta teorik anlamda ciddi bir külliyat oluşmaya başlamıştır. Bu tür teorik çalışmaların önemine rağmen Türk sineması alanında yapılan saha çalışmalarının sayıca geride kaldığı da aşikardır. Durumun eşitlenmesi gibi bir zorunluluk bulunmasa da, saha çalışmalarının sağlayacağı katkıların da göz ardı edilmemesi gerektiği düşünülmektedir.Belli bir pilot bölgeyi temel alarak elde edilen verilere dayanan saha çalışmalarının, bu bölge özelinde yaşanan sorunlara pratik yanıtlar getirebilme potansiyeli bulunmaktadır. “Yeşilçam Döneminde Van’ın Sinema Kültürü” isimli çalışma da bu açıdan önemli görülmüştür. Elde edilen sonuçların Van ilinde sinemanın gelişimine ilişkin somut bilgiler sağlaması ve başka araştırmacılar için yol g

Ārpusnodarbību sporta darba ietekme uz jauniešu un studentu fizisko sagatavotību LU Veselības un Rehabilitācijas centrā.

OpenAIRE

Kļimovs, Vadims

2006-01-01

. Atslēgvārdi: Ārpusnodarbību darbs, Veselības un rehabilitācijas centrs, biedrība ”Universitātes Sports”, atveseļošanās, relaksācija, sauna, solārijs, masāža, ūdens procedūras. Maģistra darba tēma: Ārpusnodarbību sporta darba ietekme uz jauniešu un studentu fizisko sagatavotību Latvijas Universitātes Veselības un rehabilitācijas centrā. Darba mērķis: pamatojoties uz teorētisko analīzi, pedagoģiskā izmēģinājuma darbību, izpētīt ārpusnodarbību darba ietekmi uz jauniešu un studentu ...

A new dimeric anthraquinone from endophytic Talaromyces sp. YE3016.

Science.gov (United States)

Xie, Xiao-Song; Fang, Xiao-Wei; Huang, Rong; Zhang, Shou-Peng; Wei, Hong-Xia; Wu, Shao-Hua

2016-08-01

A new unsymmetrical dimeric anthraquinone, 3-demethyl-3-(2-hydroxypropyl)-skyrin (1) was isolated from the solid-state fermentation extract of an endophytic fungal strain Talaromyces sp. YE 3016, together with five known compounds, skyrin (2), oxyskyrin (3), emodin (4), 1,3,6-trihydroxy-8-methyl-anthraquinone (5) and ergosterol (6). The structure of the new compound was elucidated on the basis of spectroscopic analysis. Compounds 1-3 exhibited moderate cytotoxic activities against MCF-7 cell line.

Development and Evaluation of the Boston University Osteoarthritis Functional Pain Short Form (BU-OA-FPS).

Science.gov (United States)

Goode, Adam P; Ni, Pengshend; Jette, Alan; Fitzgerald, G Kelley

2018-04-19

Pragmatic studies have gained popularity, thus emphasizing the need for patient-reported outcomes (PRO) to be integrated into electronic health records. This study describes the development of a customized short form from the Boston University Osteoarthritis Functional Assessment PRO (BU-OA-PRO) for a specific pragmatic clinical trial. A Functional Pain Short Form was created from an existing item bank of deidentified data in the BU-OA-PRO. Item response theory (IRT) methods were used to select items. Reliability was measured with the Cronbach alpha, then with IRT simulation methods. To examine validity, ceiling and floor effects, correlations between the short-form scores and scores from the BU-OA-PRO and the Western Ontario McMasters University Osteoarthritis Index (WOMAC) Pain and Difficulty subscales, and the area under the curve (AUC) were calculated. A minimum detectable change at 90% confidence (MDC90) was calculated based on a calibration sample. The BU-OA PRO was reduced from 126 items to 10 items to create the BU-OA Functional Pain Short Form (BU-OA-FPS). The Cronbach alpha indicated high internal consistency (0.91), and reliability distribution estimates were 0.96 (uniform) and 0.92 (normal). Low ceiling effects (4.57%), and floor effects (0%) were found. Moderate-to-high correlations between the BU-OA PRO and BU-OA-FPS were found with WOMAC Pain (BU-OA-FPS = 0.67; BU-OA-PRO = 0.64) and Difficulty (BU-OA-FPS = 0.73; BU-OA-PRO = 0.69) subscales. The correlation between the BU-OA-PRO and BU-OA-FPS was 0.94. The AUC ranged from 0.80 to 0.88. The MDC90 was approximately 6 standardized points. The BU-OA-FPS provides reliable and valid measurement of functional pain. Pragmatic studies may consider the BU-OA-FPS for use in electronic health records to capture outcomes.

Sosyal Medyada Yer Alan Markalara İlişkin Marka İmajının Güven Üzerindeki Etkisi

OpenAIRE

HACIEFENDİOĞLU, Şenol; FIRAT, Duygu

2014-01-01

İşletmeler, bugün çok önemli bir pazarlama ortamı haline gelen sosyal medyayı etkin bir şekilde kullanma çabası içindedirler. Bu çalışmada, sosyal medyada yer alan markaların marka imajının marka güveni oluşturmadaki etkisi araştırılmıştır. Araştırma, sosyal paylaşım sitelerine üye olan ve bu siteleri kullanan 483 kullanıcı üye ile yüzyüze anket yöntemi kullanılarak yapılmış ve elde edilen veriler değerlendirilmiştir. Marka imajı boyutları ile marka güveni arasındaki birebir ilişkiler korelas...

Examination of Story Books Produced Towards Preschool Children Regarding Elements of Violence and Horror Okul Öncesi Çocuklarına Yönelik Yayınlanan Hikâye Kitaplarının Şiddet ve Korku Öğeleri Açısından İncelenmesi

Directory of Open Access Journals (Sweden)

H. Elif Dağlıoğlu

2009-09-01

Full Text Available Story books are used as an indispensable tool for the education of children. Therefore, the high-quality story books that are prepared taking the age and development characteristics, needs and interests of the children into account gain even more importance. In this study, the violence and horror elements in the text and illustration parts of a total of 174 story books published in Turkey between 1995 and 2005 by 9 publishing houses, 52 of them being translations and 122 written by Turkish authors, are examined through an evaluation form created by researchers. In general, an average of 8 percent of violence and 11 percent of horror elements were found in the texts and illustrations of the story books. These elements were found mostly in translated books and books that are published under the category of world classics. Hikâye kitapları çocukların eğitiminde vazgeçilmez bir araç olarak kullanılmaktadır. Bunun için çocukların yaşları, gelişim özellikleri, ilgi ve ihtiyaçları dikkate alınarak hazırlanmış nitelikli hikâye kitapları büyük önem kazanmaktadır. Bu araştırmada Türkiye’de 1995-2005 yılları arasında 9 yayınevi tarafından basılmış 52’si çeviri, 122’si yerli olmak üzere toplam 174 hikâye kitabının metin ve resim kısımlarında bulunan şiddet ve korku öğeleri araştırmacılar tarafından oluşturulan bir değerlendirme formu ile incelenmiştir. Genel olarak hikâye kitaplarının metin ve resimlerinde ortalama % 8 şiddet, % 11 korku öğesi olduğu bulunmuştur. Söz konusu öğeler daha çok çeviri ve dünya klasikleri grubundaki kitaplarda tespit edilmiştir.

Bazı Ekmeklik Buğday Çeşitlerinin Kalitesi

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Recai Ercan

2015-02-01

Full Text Available Bu çalışmada, ülkemizde yetiştirilen başlıca buğday çeşitlerinin fiziko-kimyasal, öğütme ve ekmekçilik özellikleri saptanmıştır. Araştırmada aynı çevrelerde 1987 ve 1988 yıllarında yetiştirilen 15 buğday çeşidi kullanılmış ve çeşitlerin kalitelerini belirlemek amacıyla fiziksel, kimyasal, reolojik testler ile ekmek yapma denemeleri yapılmıştır. Buğdayların ekmekçilik özeliği çeşit özelliklerine çok fazla bağlı bulunmaktadır. Buğday çeşidi hektolitre ağırlığı, camsılık ve farinogram özellikleri üzerinde önemli etkiye sahiptir. Fakat protein miktarı, un verimi üzerine etkisi azdır. Tüm teknolojik özellikler ele alındığında Bolal-2973, Odeskaya-51, Hawk (Şahin, Sadova-1 ve Katea-1 buğday çeşitlerinin diğerlerinden üstün olduğu anlaşılmıştır.

Mitogenic activity of a water-soluble adjuvant (Bu-WSA) obtained from Bacterionema matruchotii. IV. Synergistic effects of Bu-WSA on Concanavalin A-induced proliferative response of human peripheral blood lymphocytes.

Science.gov (United States)

Nitta, T; Okumura, S; Tsushi, M; Nakano, M

1982-01-01

Butanol-extracted water-soluble adjuvant (Bu-WSA) obtained from Bacterionema matruchotii was cultured with peripheral blood mononuclear cells (PBM) in the presence of sub- and/or supra-optimal mitogenic concentrations of concanavalin A (Con A). The addition of Bu-WSA resulted in increased tritiated thymidine incorporation above that produced by Con A alone. Bu-WSA by itself is not mitogenic for PBM and in fact produced a decrease in thymidine uptake compared to the control. We investigated the response of subpopulation(s) of PBM to Bu-WSA, Con A and a mixture of Bu-WSA and Con A. Separation of PBM into purified T cells, B cells and macrophages showed that cell-cell cooperation of T cells with B cells or macrophages is necessary for the observed synergistic effect of Bu-WSA with Con A. A marked increase in thymidine incorporation by the mixture of T and B cell populations occurred, while only a small amount of thymidine was incorporated when the B cell population was absent. Mitomycin treatment revealed that the response could be ascribed to the T-cell response with a B-cell helper effect. Moreover, Con A and Bu-WSA appeared to act on the same T cell population. This model may provide unique information about the activation of human peripheral blood T cells compared with the activation of these cells by other mitogens.

Luis Buñuel: trascendiendo el tópico

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Dr. Manuel Carlos Fernández Sánchez

2001-01-01

Full Text Available En 1900 nace el cineasta Luis Buñuel en Calanda, Aragón. En el año 2000 se celebró en distintos ámbitos cinematográficos y televisivos de todo el mundo el centenario de su nacimiento. Festivales de cine, cadenas de televisión por satélite u onda hertziana, periódicos y revistas se hacen eco de la enorme trascendencia del lenguaje cinematográfico buñueliano. Este estudio sobre la última de sus películas rodada en Andalucía, concretamente en Sevilla, pretende aportar un nuevo análisis sobre esta obra que trascendió el tópico andaluz.ABSTRACIn 1900 the film director Luis Buñuel is born in Calanda, Aragón. In 2000, it took place the centennial of his birth in different film and television environments in all over the world. The transcendency of film languaje used by Buñuel has been anlysed in cinema festivals, television, newspapers and magazines. This study, focus on his last movies filmed in Andalusia, concretely in Seville, it seeks to contribute with a new analysis on this work that transcended the Andalusian topic.

tcsBU: a tool to extend TCS network layout and visualization.

Science.gov (United States)

Múrias dos Santos, António; Cabezas, Maria Pilar; Tavares, Ana Isabel; Xavier, Raquel; Branco, Madalena

2016-02-15

TCS is a widely used haplotype network reconstruction software, but lacks the capability of overlapping genetic with geographic structure, which is often a first step in phylogeographic analysis. tcsBU is a web-based program that extends the capabilities of TCS, by implementing haplotype classification into an arbitrary user-defined scheme, which is displayed as pie-chart like graphs embedded into the network. Taking advantage of modern graphic libraries, tcsBU also improves the speed at which the final network layout is reached. Networks can be saved as a Scalable Vector Graphics format. tcsBU is available on-line at http://cibio.up.pt/software/tcsBU/. The source code is freely available from https://github.com/sairum/tcsbu/ under a standard MIT license. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Bilimsel iletişimde yeşil ve altın yollarda yakınsama ve Türkiye'deki yansımaları = Convergence of the gold and green roads at scholarly communication and reflections on Turkey

Directory of Open Access Journals (Sweden)

Şengül, Gökhan

2011-01-01

Full Text Available Son yıllarda özellikle sosyal ağlarda bilgi dolaşımının artması, gelişmiş mobil iletişim cihazlarının yoğun kullanımı kısıtsız ve farklı ortamlarda bilgi erişim ve paylaşımını gerektirmektedir. Bu bağlamda bilimsel bulguların yer aldığı makalelerin geniş kitlelere ve diğer bilim insanlarının erişimine açılması; hem bilimsel eserin doğruluk ve güvenirliğini artırmaya yardımcı olmakta, hem de bilimsel verinin paylaşılmasını ve dolayısı ile de bilimsel gelişimi olumlu yönde etkilemektedir. Yaklaşık on yıldır bu amaca açık erişim insiyatifi katkı sağlamaktadır. Bu amaçla kendi kendine arşivleme (yeşil yol ve açık erişim dergisi (altın yol bilimsel çalışmaların bilim topluluğuna sunulmasında yeni yöntemler olarak takdim edilmiştir Bu çalışmada; uluslararası alanda yeşil ve altın yollar üzerinde ortaya konan kurallar irdelenmiş, yazar ve yayıncılarının oluşan iklime uyumluluğu sorgulanmış ve Türkiye adresli kurumsal arşiv ve dergilerin ortaya çıkan durum karşısında konumları üzerine bir değerlendirme yapılmıştır. Çalışma esnasında Ulrich Süreli Yayın Rehberi, Thomson Reuters (ISI Bilimsel Web (Web of Science - WoS ve Elsevier Scopus uluslararası ticari atıf veri tabanları, RoMEO, Juliet, ve ROARMAP telif politikası rehberleri, OpenDOAR, ROAR kurumsal arşiv rehberleri ve DOAJ açık erişim dergisi rehberi ile ULAKBİM ulusal veri tabanları incelenmiştir. / In parallel with the increase of information exchange rate in social networks and the usage of mobile communication devices in recent years, it is also required that the information needs to be shared and freely accessable in different enviroments. In this context freely access to the papers including scientific findings by other scientists and broad population will help to increase both the accuracy and reability of the papers. Besides it will also affect positively the

Mitogenic Activity of a Water-Soluble Adjuvant (Bu-WSA) Obtained from Bacterionema matruchotii: IV. Synergistic Effects of Bu-WSA on Concanavalin A-Induced Proliferative Response of Human Peripheral Blood Lymphocytes.

Science.gov (United States)

Nitta, Toshimasa; Okumura, Seiichi; Tsushi, Masao; Nakano, Masayasu

1982-07-01

Butanol-extracted water-soluble adjuvant (Bu-WSA) obtained from Bacterionema matruchotii was cultured with peripheral blood mononuclear cells (PBM) in the presence of sub- and/or supra-optimal mitogenic concentrations of concanavalin A (Con A). The addition of Bu-WSA resulted in increased tritiated thymidine incorporation above that produced by Con A alone. Bu-WSA by itself is not mitogenic for PBM and in fact produced a decrease in thymidine uptake compared to the control. We investigated the response of subpopulation(s) of PBM to Bu-WSA, Con A and a mixture of Bu-WSA and Con A. Separation of PBM into purified T cells, B cells and macrophages showed that cell-cell cooperation of T cells with B cells or macrophages is necessary for the observed synergistic effect of Bu-WSA with Con A. A marked increase in thymidine incorporation by the mixture of T and B cell populations occurred, while only a small amount of thymidine was incorporated when the B cell population was absent. Mitomycin treatment revealed that the response could be ascribed to the T-cell response with a B-cell helper effect. Moreover, Con A and Bu-WSA appeared to act on the same T cell population. This model may provide unique information about the activation of human peripheral blood T cells compared with the activation of these cells by other mitogens. © owned by Center for Academic Publications Japan (Publisher).

ANALISIS KEPUASAN DAN LOYALITAS KONSUMEN TERHADAP TINGKAT PENJUALAN DI WARUNG BU KRIS (Studi Kasus Pada Ayam Penyet Sebagai Menu Unggulan Warung Bu Kris

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Theresia Widyaratna

2001-01-01

Full Text Available The economic fluctuations in Indonesia apparently do not influence the food and beverage business. This business still goes well, because people need food. Food is a primary need that must be met and is not influenced by economic conditions in Indonesia. One food and beverage business is Warung Bu Kris, in Surabaya. This restaurant offers various choices. Most of the food served is pressed (penyet and blended with fresh chile sauce (sambal. Many people like this food and usually choose this kind of food as their first choice. The restaurant is usually full of people. Although there are not any seats, customers are willing to wait in order to eat their favorite food. The sample was chosen using non-random sampling. Data were collected in two steps, first to determine the favorite menu of Warung Bu Kris. The second step was to examine the relationship between customer satisfaction and loyalty, then to examine the relationship between both customer satisfaction and loyalty with sales at Warung Bu Kris. The weighted mean formula is used to analyze data in the beginning survey. For the second step, correlation is used. The results show that chicken penyet is the favorite dish at Warung Bu Kris. There is an association between satisfaction and loyalty and also between both customer satisfaction and loyalty with sales. These results suggest that Warung Bu Kris should improve product quality and service in order to maintain customer loyalty. The results can also give further information to other entrepreneurs who will open this type of business in the future. Abstract in Bahasa Indonesia : Fluktuasi ekonomi di Indonesia ternyata tidak mempengaruhi industri makanan dan minuman. Jenis usaha tersebut masih berjalan lancar karena masyarakat membutuhkan makanan. Makanan merupakan kebutuhan primer yang harus dipenuhi dan tidak terpengaruh oleh keadaan ekonomi di Indonesia. Salah satu usaha makanan dan minimum adalah Warung Bu Kris di Surabaya. Tempat makan

CMS RPC detectors assembled in Pakistan installed on the backside of the YE+1 endcap yoke

CERN Multimedia

Walter Van Doninck, VUB-Brussels and CERN

2006-01-01

Resistive Plate Chambers (RPCs) are sensitive to the passage of muons and provide a "trigger" signal for CMS. This image shows RPC detectors, which were assembled in Pakistan, installed on the backside of an endcap yoke disc, known as YE+1.

Energy diffusion and the butterfly effect in inhomogeneous Sachdev-Ye-Kitaev chains

Directory of Open Access Journals (Sweden)

Yingfei Gu, Andrew Lucas, Xiao-Liang Qi

2017-05-01

Full Text Available We compute the energy diffusion constant $D$, Lyapunov time $\\tau_{\\text{L}}$ and butterfly velocity $v_{\\text{B}}$ in an inhomogeneous chain of coupled Majorana Sachdev-Ye-Kitaev (SYK models in the large $N$ and strong coupling limit. We find $D\\le v_{\\text{B}}^2 \\tau_{\\text{L}}$ from a combination of analytical and numerical approaches. Our example necessitates the sharpening of postulated transport bounds based on quantum chaos.

Trakyada Yeşilyurt Gazetesine Göre 1944 Yılında II. Dünya Savaşı ve Kırklareli

Directory of Open Access Journals (Sweden)

Türkan Vahibe DOĞRUÖZ

2016-08-01

Full Text Available Gazeteler günlük ya da haftalık olarak, özel bir konuda veya genel konularla ilgili güncel olayları ve gelişmeleri okuyucularına ileten yazılı belgelerdir. Bu belgeler aynı zamanda yayınladıkları dönemi günümüze taşıyan birincil kaynaklardır. İl özelinde çıkan yerel gazetelerde ilde yaşanan siyasi, ekonomik, sosyal ve kültürel gelişmelere ilişkin okuyuculara ve araştırmacılara bilgi sağlarlar. Ali Rıza Dursunkaya tarafından 31 Ağustos 1925 tarihinde yayın hayatına başlayan Trakya’da Yeşilyurt gazetesi de Kırklareli’nin ilk yerel gazetesi olma özelliğini taşımaktadır. Günümüze kadar yayım hayatına devam eden gazete Kırklareli’nde yaşanan siyasi, ekonomik, sosyal ve kültürel olayları bizlere ulaştırmaya devam etmektedir. Çalışmamızda Trakya’da Yeşilyurt gazetesinin II. Dünya Savaşı’nın son yıllarına rastlayan 1944 yılına ait 07 2. Kanun (Ocak 1944- 29 2. Kanun 1944 tarihleri arasında haftada iki gün Salı ve Cuma günleri yayımlanan 1313-1413 sayıları incelenecektir. Böylece Türkiye’nin II. Dünya Savaşı sırasında yaşadığı zor günler Kırklareli örneği ile anlatılmaya çalışılacaktır. Amacımız II. Dünya Savaşı’nın yaşandığı günlerde siyasi, ekonomik, sosyal ve kültürel açıdan Kırklareli’nde yaşananları o günün gazete haberlerini kronolojik bir sıra takip ederek mevcut durumu incelemektir. Trakya’da Yeşilyurt gazetesi ile ilgili olarak böyle bir çalışmanın daha önce yapılmamış olması göz önüne alındığında dönemle ilgili Kırklareli iline yeni bir bakış açısı getireceği düşünülmektedir. İkinci Dünya Savaşı’nın son yıllarına tekabül eden ve Türkiye’nin zor zamanlarına tanıklık etmiş savaş haberleri dışında eğitim, ekonomi, tarım kooperatif, kültür, sanat, sağlık, spor, haberleriyle halka ışık tutacaktır.

KİŞİYE ÖZEL DENTAL İMPLANT ABUTMENTLARI

OpenAIRE

ÖZTÜRK, Özgür

2015-01-01

ÖZETDişsiz alanların implant destekli protez ile restorasyonu günümüzde konvansiyonel protetik tedavilere karşı geçerli bir tedavi seçeneği haline gelmiştir. İmplant destekli restorasyonların başarısında implant ile restorasyon arasındaki bağlantı oldukça önemlidir. Diş çekim sonrası alveol kemiği ve yumuşak dokuda oluşan değişiklikler kişiden kişiye fark etmektedir. Bu nedenle her vakada prefabrike abutmentlar ile uygun bağlantı ve yumuşak doku konturu elde edilememektedir. Bu durumlarda kiş...

Concept of BuBc in neonatal jaundice – needs a change

OpenAIRE

Singh, Kalpana; Borrison, Auxilia; Mahdi, Abbas Ali

2014-01-01

Orthoclinical diagnostics Vitros microslide came with a method by which Bu and Bc can be estimated directly. The advantage of this microslide technology is that conjugated bilirubin (Bc) does not contain delta bilirubin and the fractions i.e BuBc are actually estimated. TBil estimation is also available based on traditional diazo method on the same instrument

Analysis of poultry eating and drinking behavior by software eYeNamic

OpenAIRE

A. De Montis; A. Pinna; M. Barra; E. Vranken

2013-01-01

Constant presence of at least one operator in livestock buildings for broilers would allow a perfect control of animal behaviour and, especially, deviations in feeding and drinking patterns, in the perspective of a high welfare status. However, as nowadays it is impossible for a farmer to be present in the farm all day long, automatic monitoring systems are required. The purpose of this paper is to introduce a system (eYeNamic) for automatic monitoring and analyzing broilers’ behavior in a fa...

Biosurfactants from Acinetobacter calcoaceticus BU03 enhance the solubility and biodegradation of phenanthrene.

Science.gov (United States)

Zhao, Zhenyong; Wong, Jonathan W C

2009-03-01

A thermophilic bacterial strain, Acinetobacter calcoaceticus BU03, with a biosurfactant-producing capability, was isolated from petroleum-contaminated soil with an improved procedure which employed the solubilization of polycyclic aromatic hydrocarbons (PAHs), i.e. naphthalene in agar plate, as a selection criterion. Crude biosurfactant was recovered from the culture of BU03 by extraction with n-hexane, and its properties were investigated. Biosurfactants from A. calcoaceticus BU03 constitute a thermo-stable mixture, composed of different agents with surface activities. At their critical micelle concentration (CMC) of 152.4 mg L(-1), the crude biosurfactants produced from A. calcoaceticus BU03 decreased the air-water surface tension to 38.4 mN m(-1). In thermophilic conditions, the emulsifying activity is 2.8 times that of Tween 80. The effects of the biosurfactants produced by A. calcoaceticus on the solubility and biodegradation of PAHs were investigated in batch systems. Biosurfactants produced by A. calcoaceticus BU03 at 25 times their CMC significantly increased the apparent aqueous solubility of phenanthrene (PHE), pyrene (PYR) and benzo(a)pyrene (B[a]P) to 54.3, 6.33 and 2.08 mg L(-1), respectively. In aqueous system, the biosurfactants at concentrations of 0.5 CMC and 1 CMC slightly enhanced the biodegradation of PHE by a consortium of PAH-degrading microrganisms. Results indicate that biosurfactants from A. calcoaceticus BU03 have potential to enhance the removal of PAHs from contaminated sites.

Detailed structural characterization of the grafting of [Ta(=CHtBu)(CH2tBu)3] and [Cp*TaMe4] on silica partially dehydroxylated at 700 C and the activity of the grafted complexes toward alkane metathesis

Energy Technology Data Exchange (ETDEWEB)

Le Roux, Erwan; Chabanas, Mathieu; Baudouin, Anne; de Mallmann, Aimery; Coperet, Christophe; Quadrelli, E. Allesandra; Thivolle-Cazat, Jean; Basset, Jean-Marie; Lukens, Wayne; Lesage, Anne; Emsley, Lyndon; Sunley, Glenn J.

2004-08-30

The reaction of [Ta({double_bond}CHtBu)(CH{sub 2}tBu){sub 3}] or [Cp*Ta(CH{sub 3}){sub 4}] with a silica partially dehydroxylated at 700 C gives the corresponding monosiloxy surface complexes [({triple_bond}SiO)Ta({double_bond}CHtBu)(CH{sub 2}tBu){sub 2}] and [({triple_bond}SiO)Ta(CH{sub 3}){sub 3}Cp*] by eliminating a {sigma}-bonded ligand as the corresponding alkane (H-CH{sub 2}tBu or H-CH{sub 3}). EXAFS data show that an adjacent siloxane bridge of the surface plays the role of an extra surface ligand, which most likely stabilizes these complexes as in [({triple_bond}SiO)Ta({double_bond}CHtBu)(CH{sub 2}tBu){sub 2}({triple_bond}SiOSi{triple_bond})] (1a') and [({triple_bond}SiO)Ta(CH{sub 3}){sub 3}Cp*({triple_bond}SiOSi{triple_bond})] (2a'). In the case of [({triple_bond}SiO)Ta({double_bond}CHtBu)(CH{sub 2}tBu){sub 2}({triple_bond}SiOSi{triple_bond})], the structure is further stabilized by an additional interaction: a C-H agostic bond as evidenced by the small J coupling constant for the carbenic C-H (H{sub C-H} = 80 Hz), which was measured by J-resolved 2D solid-state NMR spectroscopy. The product selectivity in propane metathesis in the presence of [({triple_bond}SiO)Ta({double_bond}CHtBu)-(CH{sub 2}tBu){sub 2}({triple_bond}SiOSi{triple_bond})] (1a') as a catalyst precursor and the inactivity of the surface complex [({triple_bond}SiO)Ta-(CH{sub 3}){sub 3}Cp*({triple_bond}SiOSi{triple_bond})] (2a') show that the active site is required to be highly electrophilic and probably involves a metallacyclobutane intermediate.

Thermodynamic characteristics of solutions of Bu4NI in dimethylsulfoxide over a wide concentration range

International Nuclear Information System (INIS)

Safonova, L.P.; Shmukler, L.Eh.; Kolker, A.M.

2008-01-01

The integral heats of solution of Bu 4 NI in dimethylsulfoxide (DMSO) were measured at 298.15, 313.15, and 328.15 K and concentrations from dilute to saturation. The standard enthalpies and heat capacities of solution and solvation of Bu 4 NI in DMSO at various temperatures and the C-bar p 0 (Bu 4 N + ) value at 298.15 K were calculated. The obtained and literature data were used to consider the influence of the nature of solvents on Δ sol H m (Bu 4 NI) and of the electrolyte on Δ sol H m in dimethylsulfoxide at 298.15 K. The dynamic viscosity and density of the Bu 4 NI-DMSO system were determined at various concentrations and temperatures. The Eyring equation was used to calculate the activation energy of viscous flow at all the concentrations studied [ru

Tritium labelling of highly selective probes for. delta. -opioid receptors: ( sup 3 H)Tyr-D-Ser(O-t-Bu)-Gly-Phe-Leu-Thr(DSTBULET) and ( sup 3 H)Tyr-D-Ser(O-t-Bu)-Gly-Phe-Leu-Thr(O-t-Bu)(BUBU)

Energy Technology Data Exchange (ETDEWEB)

Fellion, E.; Gacel, G.; Roques, B.P. (Institut National de la Sante et de la Recherche Medicale (INSERM), 75 - Paris (France)); Roy, J.; Morgat, J.L. (CEA Centre d' Etudes Nucleaires de Saclay, 91 - Gif-sur-Yvette (France). Service de Biochimie)

1990-08-01

The introduction of bulky residue(s) in linear enkephalin-related hexapeptides represents a new approach in the design of selective probes for {delta}-opioid receptors, displaying the appropriate criteria to investigate biological and pharmacological properties of the assumed binding site ({delta}) of endogenous enkephalins. The selectivities and high affinities of Tyr-D-Ser(O-t-Bu)-Gly-Phe-Leu-Thr(DSTBULET) and especially Tyr-D-Ser(O-t-Bu)Gly-Phe-Leu-Thr(O-t-Bu) (BUBU) associated with a satisfactory resistance to peptidases, make them the most suitable {delta}-probes reported to date. In the present paper, we report the synthesis of DSTBULET and BUBU under tritiated forms with high specific radioactivities. These radio-labelled probes will enable extensive in vitro and in vivo investigations of {delta}-opioid receptors properties to be carried out. (author).

The evolution of pegmatite-hosted Sn-W mineralization at Nong Sua, Thailand: Evidence from fluid inclusions and stable isotopes

Science.gov (United States)

Linnen, Robert L.; Williams-Jones, Anthony E.

1994-01-01

The Nong Sua aplite-pergmatite complex contains two dominant styles of Sn-W-Ta-Nb mineralization. Cassiterite ± Nb-Ta-Ti oxide minerals are disseminated in the pegmatite, and cassiterite and wolframite are hosted by quartz-tourmaline veins which are contained solely within aplite. The orthomagmatic fluid at Nong Sua is preserved as primary fluid inclusions in the cores of magmatic garnet crystals that have high tin concentrations (garnet cores without fluid inclusions do not contain elevated tin concentrations). These fluid inclusions have a composition of 3 wt% NaCl eq. The low salinity suggests that, at vapor saturation, tin was partitioned in favour of the melt, which allowed cassiterite to initially crystallize directly from the melt. Primary, pseudosecondary, and secondary fluid inclusions in cassiterite, tourmaline, and quartz record three-component mixing of the orthomagmatic fluid with high salinity aqueous and with CO 2-rich fluids. The orthomagmatic water is interpreted to have had δ 18O value of +8.7 to +9.9 per mil and a δD value of -72 to -78 per mil from δ18O analyses of muscovite and quartz, and δD of muscovite. The δ18O composition of muscovite decreased from 10.1 to 8.0 per mil and δD increased from - 106 to - 85 per mil, from the magmatic to the hydrothermal stages of pegmatite evolution. These changes are consistent with an influx of metamorphic fluids or evolved meteoric waters. We consider that the saturation of the melt with vapor caused the pressure in the pegmatite to rise to approximately 3.8 kbar, at a temperature of 650°C. Fluid overpressure caused the aplite to fracture, and veins to form from fluids which migrated into the fracture-induced low pressure zones. This event can be modeled by an isothermal decompression to 2.7 kbar. Cassiterite deposition was probably controlled by increasing fO 2, whereas wolframite deposition resulted from the mixing of W-rich with Fe-Mn-rich fluids. In both cases decompression, cooling, and

WebQuest mācību modeļa izmantošana ķīmijas mācību stundās

OpenAIRE

Silauniece, Līga

2010-01-01

Darbā veikta literatūras izpēte par WebQuest kā interneta izmantošanas modeli ķīmijas mācību procesā. Analizēta WebQuest projekta sagatavošana un realizēšana, organizatoriskie un didaktiskie aspekti. Izveidots WebQuest darba apraksta piemērs ķīmijā 9. klasei. Izstrādātas vietnes par WebQuest mācību modeļa realizāciju. Izstrādāta pedagogu profesionālās pilnveides kursu programma un metodiskie ieteikumi skolotājiem.

KONYA ANA TAHLİYE KANALINDA KLORLU BİLEŞİKLERİN BELİRLENMESİ

Directory of Open Access Journals (Sweden)

Mehmet Emin AYDIN

2000-03-01

Full Text Available Konya ana tahliye kanalı Konya ovasının drenaj sularını toplayarak tuz gölüne boşaltmaktadır. Konya ovasında Konya şehri atık sularının tabi bir drenaj noktası bulunmaması sebebiyle kent atıksuları da bu kanala deşarj edilmektedir. Kanal güzergahı boyunca bu drenaj suları ve atık sular sulama suyu olarak kullanılmaktadır. Bazı klorlu organik bileşikler toksik ve kanserojen oldukları bilinen bileşiklerdir. Bu çalışmada Konya atıksularının deşarj edildiği ana tahliye kanalından alınan saatlik, günlük ve aylık numuneler gaz kromotoğraf (GC ile analiz edilerek klorlu organik bileşik içerikleri araştırılmıştır.

Antipsychotic-like effect of the muscarinic acetylcholine receptor agonist BuTAC in non-human primates.

Directory of Open Access Journals (Sweden)

Maibritt B Andersen

Full Text Available Cholinergic, muscarinic receptor agonists exhibit functional dopamine antagonism and muscarinic receptors have been suggested as possible future targets for the treatment of schizophrenia and drug abuse. The muscarinic ligand (5R,6R-6-(3-butylthio-1,2,5-thiadiazol-4-yl-1-azabicyclo[3.2.1]octane (BuTAC exhibits high affinity for muscarinic receptors with no or substantially less affinity for a large number of other receptors and binding sites, including the dopamine receptors and the dopamine transporter. In the present study, we wanted to examine the possible antipsychotic-like effects of BuTAC in primates. To this end, we investigated the effects of BuTAC on d-amphetamine-induced behaviour in antipsychotic-naive Cebus paella monkeys. Possible adverse events of BuTAC, were evaluated in the same monkeys as well as in monkeys sensitized to antipsychotic-induced extrapyramidal side effects. The present data suggests that, the muscarinic receptor ligand BuTAC exhibits antipsychotic-like behaviour in primates. The behavioural data of BuTAC as well as the new biochemical data further substantiate the rationale for the use of muscarinic M1/M2/M4-preferring receptor agonists as novel pharmacological tools in the treatment of schizophrenia.

COMPARATION STUDY OF INSTANT NOODLE NONG SHIM KOREA AND INDOMIE INDONESIA AS THE FEFFECT OF PACKAGING DESIGN POINT OF INTEREST TO THE CONSUMER BRAND PREFERENCE

Directory of Open Access Journals (Sweden)

Listia Natadjaja

2003-01-01

Full Text Available Sudah sejak lama%2C masyarakat mengkonsumsi mie instant. Di Korea mi instan yang disebut Ramyon%2C adalah salah satu makanan yang popular dan banyak dijual di toko-toko kecil%2C supermarket%2C restoran dan kantin. Mi instan yang terkenal di Korea diproduksi oleh Nong Shim Co.%2C Ltd. Di Indonesia%2C kebanyakan orang mengkonsumsi mi instan dengan alasan praktis%2C cepat saji dan lain sebagainya. Indomie%2C yang diproduksi oleh PT. Indofood adalah merk nomor satu dan menjadi pemimpin pasar pada pasar mi instan. Dalam studi komparasi antara dua merk terkenal ini%2C perlu diketahui seberapa jauh peran desain kemasan dalam menarik minat konsumen terhadap pilihan merk. Abstract in Bahasa Indonesia : For a long time%2C people have consumed the instant noodle. In Korea%2C instant noodle%2C which is called Ramyon%2C is one of popular food and it is often seen in the retail shop%2C supermarket%2C restaurant and cafeteria. Instant noodle that has a famous brand in Korea is produce by Nong Shim Co.%2C Ltd. In Indonesia%2C many people have consumed the instant noodle with practice reason%2C fast serving%2C and etc. Indomie%2C produced by PT. Indofood%2C is the number one brand and become the market leader of instant noodle. Comparing at two famous brand of instant noodle%2C it is needed to be known how far the effect of packaging design can attract the consumer brand preference. desain kemasan%2C pilihan merk%2C mi instan.

Photovoltaic Performance and Characteristics of Dye-Sensitized Solar Cells Prepared with the N719 Thermal Degradation Products Ru(LH)(2)(NCS)(4-tert-butylpyridine) N(Bu)(4) and Ru(LH)(2)(NCS)(1-methylbenzimidazole) N(Bu)(4)

DEFF Research Database (Denmark)

Nguyen, P. T.; Binh, X. T. L.; Andersen, A. R.

2011-01-01

The dye-sensitized solar cell N719 thermal degradation products [Ru(LH)(2)(NCS)(4-tert-butylpyridine)][N(Bu)(4)] (1) and [Ru(LH)(2)(NCS)(1-methylbenzimidazole)][N(Bu)(4)] (2) were synthesized from [Ru(LH)(2)(NCS)(2)][N(Bu)(4)](2) (N719), (L = 2,2'-bipyridyl-4,4'-dicarboxylic acid) and characterized...

The thermodynamic characteristics of solutions of Bu4NI in dimethylsulfoxide over a wide concentration range

Science.gov (United States)

Safonova, L. P.; Shmukler, L. E.; Kolker, A. M.

2008-05-01

The integral heats of solution of Bu4NI in dimethylsulfoxide (DMSO) were measured at 298.15, 313.15, and 328.15 K and concentrations from dilute to saturation. The standard enthalpies and heat capacities of solution and solvation of Bu4NI in DMSO at various temperatures and the bar C_p^o (Bu_4 N^ + ) value at 298.15 K were calculated. The obtained and literature data were used to consider the influence of the nature of solvents on Δsol H m (Bu4NI) and of the electrolyte on Δsol H m in dimethylsulfoxide at 298.15 K. The dynamic viscosity and density of the Bu4NI-DMSO system were determined at various concentrations and temperatures. The Eyring equation was used to calculate the activation energy of viscous flow at all the concentrations studied.

Synthesis of Au38(SCH2CH2Ph)24, Au36(SPh-tBu)24, and Au30(S-tBu)18 Nanomolecules from a Common Precursor Mixture.

Science.gov (United States)

Rambukwella, Milan; Dass, Amala

2017-10-17

Phenylethanethiol protected nanomolecules such as Au 25 , Au 38 , and Au 144 are widely studied by a broad range of scientists in the community, owing primarily to the availability of simple synthetic protocols. However, synthetic methods are not available for other ligands, such as aromatic thiol and bulky ligands, impeding progress. Here we report the facile synthesis of three distinct nanomolecules, Au 38 (SCH 2 CH 2 Ph) 24 , Au 36 (SPh-tBu) 24 , and Au 30 (S-tBu) 18 , exclusively, starting from a common Au n (glutathione) m (where n and m are number of gold atoms and glutathiolate ligands) starting material upon reaction with HSCH 2 CH 2 Ph, HSPh-tBu, and HStBu, respectively. The systematic synthetic approach involves two steps: (i) synthesis of kinetically controlled Au n (glutathione) m crude nanocluster mixture with 1:4 gold to thiol molar ratio and (ii) thermochemical treatment of the purified nanocluster mixture with excess thiols to obtain thermodynamically stable nanomolecules. Thermochemical reactions with physicochemically different ligands formed highly monodispersed, exclusively three different core-size nanomolecules, suggesting a ligand induced core-size conversion and structural transformation. The purpose of this work is to make available a facile and simple synthetic method for the preparation of Au 38 (SCH 2 CH 2 Ph) 24 , Au 36 (SPh-tBu) 24 , and Au 30 (S-tBu) 18 , to nonspecialists and the broader scientific community. The central idea of simple synthetic method was demonstrated with other ligand systems such as cyclopentanethiol (HSC 5 H 9 ), cyclohexanethiol(HSC 6 H 11 ), para-methylbenzenethiol(pMBT), 1-pentanethiol(HSC 5 H 11 ), 1-hexanethiol(HSC 6 H 13 ), where Au 36 (SC 5 H 9 ) 24 , Au 36 (SC 6 H 11 ) 24 , Au 36 (pMBT) 24 , Au 38 (SC 5 H 11 ) 24 , and Au 38 (SC 6 H 13 ) 24 were obtained, respectively.

Structure of α-conotoxin BuIA: influences of disulfide connectivity on structural dynamics

Directory of Open Access Journals (Sweden)

Craik David J

2007-04-01

Full Text Available Abstract Background α-Conotoxins have exciting therapeutic potential based on their high selectivity and affinity for nicotinic acetylcholine receptors. The spacing between the cysteine residues in α-conotoxins is variable, leading to the classification of sub-families. BuIA is the only α-conotoxin containing a 4/4 cysteine spacing and thus it is of significant interest to examine the structure of this conotoxin. Results In the current study we show the native globular disulfide connectivity of BuIA displays multiple conformations in solution whereas the non-native ribbon isomer has a single well-defined conformation. Despite having multiple conformations in solution the globular form of BuIA displays activity at the nicotinic acetylcholine receptor, contrasting with the lack of activity of the structurally well-defined ribbon isomer. Conclusion These findings are opposite to the general trends observed for α-conotoxins where the native isomers have well-defined structures and the ribbon isomers are generally disordered. This study thus highlights the influence of the disulfide connectivity of BuIA on the dynamics of the three-dimensional structure.

A hydrogeological investigation of the Yeşilyurt (Isparta-Sütçüler plain

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Suat Taşdelen

2002-03-01

Full Text Available Investigation area is almost 10 km in the north-west of Sütçüler country of Isparta and covers 60 km2 area. Firstly, detailed geological and hydrological investigation of Yeşilyurt Plain surface drainage area has been performed. Long term monitoring and analyses have been done for direction of hydrological investigation. An isohiyetal map was prepared for the investigation area. Water table maps were drawn by means of deep and shallow boreholes in the plain and flow direction was determined (October 2000. Water which was collected at boreholes was chemically analyzed to determine the characteristic of water for domestic use, irrigation and industrial purposes. In order to achieve this, the anion and cation concentrations, ionization abilities ionic activity, calcite dolomite sulphate saturation indexes and the partial pressures of dissolved CO2 were calculated and the results were interpreted. In addition, water has been classified according to chemical contend and use purpose by means of Wilcox, USA Salinity Laboratory, Piper and Schoeller diagrams and similarities in the origins of waters were investigated. During the study, a groundwater budget of Yeşilyurt Plain was prepared in the light of obtained data and optimum output of groundwater has been calculated.

Cesarzowa Bułgarów, augusta i bazylisa – Maria-Irena Lekapena i transfer bizantyńskiej idei kobiety-władczyni (imperial feminine w średniowiecznej Bułgarii

Directory of Open Access Journals (Sweden)

Zofia A. Brzozowska

2017-10-01

Full Text Available Empress of Bulgarians, augusta and basilissa – Maria-Irene Lekapene and the transfer of the idea of imperial feminine in the Medieval Bulgaria Maria Lekapene was a granddaughter of Byzantine Emperor Romanos I Lekapenos. In 927 she married Peter I of Bulgaria. Her marriage, ceremoniously entered into in Constantinople, aimed to strengthen the newly signed Byzantine-Bulgarian peace treaty. Historians attributed to the Empress a significant impact on the political moves of her husband. The Empress was also to introduce a lot of elements of the Byzantine theory of power in Bulgaria.   Cesarzowa Bułgarów, augusta i bazylisa – Maria-Irena Lekapena i transfer bizantyńskiej idei kobiety-władczyni (imperial feminine w średniowiecznej Bułgarii Maria Lekapena była wnuczką cesarza bizantyńskiego Romana I Lekapena. W 927 roku poślubiła władcę Bułgarii, Piotra. Jej małżeństwo, uroczyście zawarte w Konstantynopolu, miało za zadanie umocnić dopiero co podpisany pokój bizantyńsko-bułgarski. Historycy przypisywali carycy znaczny wpływ na polityczne posunięcia jej męża. Władczyni miała też zaszczepić na gruncie bułgarskim wiele elementów bizantyńskiej teorii władzy.

Sosyal Ağlar ve E-Paylaşım: Kalitatif Bir Analiz / Social Media and Word of Mouse: A Qualitative Research

OpenAIRE

OZTURK, Eda

2018-01-01

Ağızdan ağıza reklam en eski reklam türlerinden biridir. Son yıllardaki hızlı gelişiminin altında yatan güç ise internetin yükselişi olmuştur. İnternet ağızdan ağıza reklam için yeni kanallar yaratmıştır. Sosyal Paylaşım siteleri bu yeni kanallar içerisinde en önde gelenlerden birini oluşturmaktadır. Tüm bu gelişmelere rağmen internette ağızdan ağıza reklam halen yeni bir olgudur ve alanda konuya dair sınırlı sayıda çalışma bulunmaktadır. Bu nedenle bu çalışmada önce uygulamanın gelişimine ye...

Web Quest mācību modeļa izmantošana ķīmijas mācību priekšmeta apguvē

OpenAIRE

Blumberga, Arta

2010-01-01

Diplomdarbā apkopota un analizēta informācija par WebQuest mācību modeli, kas ir uz izziņu balstīts, projekt- un problēmorientēts mācību modelis, kurā skolēni izmanto galvenokārt interneta informāciju. Balstoties uz apkopoto informāciju, tika izveidots WebQuest darba apraksts ķīmijā, kas aprobēts Rīgas 46. vidusskolā. Izmantojot anketēšanas metodi, veikta izveidotā projekta darba novērtēšana.

Mācību modeļa "WebQuest"izmantošana angļu valodas apguvē

OpenAIRE

Jēgermane, Ilze

2011-01-01

Mācību modelis WebQuest ir inovatīva metode mācību procesā, kuru sākotnēji izveidoja un izstrādāja mācību tehnoloģiju profesors Bērnijs Dodžs (Bernie Dodge) kā vienu no mācību metodēm izmantojot internetu. Pētījuma mērķis bija izpētīt, kā mācību modelis WebQuest var būt lietderīgs angļu valodas apguvē. Darba autore analizēja teorētisko literatūru par mācību modeļa WebQuest koncepciju un tā pielietojumu angļu valodas kā svešvalodas apguvē, izmantojot gadījuma pētījuma metodi. Pētījumā piedalīj...

Skolotāju uztvertā stresa saistība ar apmierinātību ar darbu

OpenAIRE

Dejus, Ilze

2014-01-01

Pētījuma „Skolotāju uztvertā stresa saistība ar apmierinātību ar darbu” mērķis, pamatojoties uz teorētisko analīzi, pētīt skolotāju uztvertā stresa saistību ar apmierinātību ar darbu. Pētījuma jautājumi: 1.Vai pastāv statistiski nozīmīga saistība starp skolotāju uztvertā stresa līmeni un apmierinātību ar darbu? 2.Vai pastāv statistiski nozīmīgas atšķirības starp Liepājas 15.vidusskolas un Grobiņas novada skolotāju uztvertā stresa līmeni un apmierinātību ar darbu? Aptaujāti 113 skolot...

[Experience of treatment and understanding of impediment disease in Shen nong ben cao jing (Shen-ntonz's Classic of Materia Medica)].

Science.gov (United States)

Ding, Hongchang; Wang, Zhenrui

2015-01-01

As a book with significant historical materials for the research of impediment disease not to be ignored, Shen nong ben cao jing (Shennong's Classic of Materia Medica) contains, among its 365 kinds of materia medica, 75 kinds of medicines related to impediment disease. Among the latter ones, 51 are related to "damp impediment", "cold-damp impediment", "wind-cold-damp impediment", "wind impediment", "wind-damp impediment", and "cold impediment"; 16 are related to "laryngeal impediment", "general impediment", and "blood impediment"; 8 are related to "muscular impediment", "stomach impediment", "hernia-conglomeration impediment", "internal consumptive-thirst impediment", "wilting impediment", and "hemiplegic impediment". To systematically analyze the properties, tastes, and effects of these medicines and its related knowledge, and then further explore the overall recognition and their treating experience of the physicians at that period would not only enrich the historical research on impediment disease, but also offer much help and reference to the understanding and treatment of impediment for contemporary clinicians.

Study of the Treatment of the Liquid Radioactive Waste Nong Son Uranium Ore Processing

International Nuclear Information System (INIS)

Nguyen Ba Tien; Trinh Giang Huong; Luu Cao Nguyen; Harvey, L.K.; Tran Van Quy

2011-01-01

Liquid waste from Nong Son uranium ore processing is treated with concentrated acid, agglomerated, leached, run through ion exchange and then treated with H 2 O 2 to precipitate yellowcake. The liquid radioactive waste has a pH of 1.86 and a high content of radioactive elements, such as: [U] 143.898 ppm and [Th] = 7.967 ppm. In addition, this waste contains many polluted chemical elements with high content, such as arsenic, mercury, aluminum, iron, zinc, magnesium, manganese and nickel. The application of the general method as one stage precipitation or precipitation in coordination with BaCl 2 is not effective. These methods generated a large amount of sludge with poor settling characteristics. The volume of final treated waste was large. This paper introduces the investigation of the treatment of this liquid radioactive waste by the method of two stage of precipitation in association with polyaluminicloride (PAC) and polymer. The impact of factors: pH, neutralizing agents, quantity of PAC and polymer to effect precipitation and improve the settling characteristics during processing was studied. The results showed that the processing of liquid radioactive waste treatment through two stages: first stage at pH = 3 and the second stage at pH = 8.0 with limited PAC and polymer (A 101) resulted in significant reduced volume of the treated waste. The discharged liquid satisfied the requirement of the National Technical Regulation on Industrial Waste Water (QCVN 24:2009). (author)

Completion of cathode strip chamber (CSC) installation on the so-called YE+2 wheel of CMS on March 2005.

CERN Multimedia

Tejinder S. Virdee

2005-01-01

The pictures have been taken in the CMS construction hall in Cessy (neighbouring France), called SX5, in March 2005 and show the status of cathode strip chamber (CSC) assembly on the yoke disk YE+2. The chambers are labelled ME+3 and their installation has been completed on March 16th, 2005.

BuD, a helix–loop–helix DNA-binding domain for genome modification

Energy Technology Data Exchange (ETDEWEB)

Stella, Stefano [Spanish National Cancer Research Centre (CNIO), Calle de Melchor Fernández Almagro 3, 28029 Madrid (Spain); University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen (Denmark); Molina, Rafael; López-Méndez, Blanca [Spanish National Cancer Research Centre (CNIO), Calle de Melchor Fernández Almagro 3, 28029 Madrid (Spain); Juillerat, Alexandre; Bertonati, Claudia; Daboussi, Fayza [Cellectis, 8 Rue de la Croix Jarry, 75013 Paris (France); Campos-Olivas, Ramon [Spanish National Cancer Research Centre (CNIO), Calle de Melchor Fernández Almagro 3, 28029 Madrid (Spain); Duchateau, Phillippe [Cellectis, 8 Rue de la Croix Jarry, 75013 Paris (France); Montoya, Guillermo, E-mail: guillermo.montoya@cpr.ku.dk [Spanish National Cancer Research Centre (CNIO), Calle de Melchor Fernández Almagro 3, 28029 Madrid (Spain); University of Copenhagen, Blegdamsvej 3B, 2200 Copenhagen (Denmark)

2014-07-01

Crystal structures of BurrH and the BurrH–DNA complex are reported. DNA editing offers new possibilities in synthetic biology and biomedicine for modulation or modification of cellular functions to organisms. However, inaccuracy in this process may lead to genome damage. To address this important problem, a strategy allowing specific gene modification has been achieved through the addition, removal or exchange of DNA sequences using customized proteins and the endogenous DNA-repair machinery. Therefore, the engineering of specific protein–DNA interactions in protein scaffolds is key to providing ‘toolkits’ for precise genome modification or regulation of gene expression. In a search for putative DNA-binding domains, BurrH, a protein that recognizes a 19 bp DNA target, was identified. Here, its apo and DNA-bound crystal structures are reported, revealing a central region containing 19 repeats of a helix–loop–helix modular domain (BurrH domain; BuD), which identifies the DNA target by a single residue-to-nucleotide code, thus facilitating its redesign for gene targeting. New DNA-binding specificities have been engineered in this template, showing that BuD-derived nucleases (BuDNs) induce high levels of gene targeting in a locus of the human haemoglobin β (HBB) gene close to mutations responsible for sickle-cell anaemia. Hence, the unique combination of high efficiency and specificity of the BuD arrays can push forward diverse genome-modification approaches for cell or organism redesign, opening new avenues for gene editing.

Synthesis and Characterization of Tert-Butylgallium-Antimony Compounds; X-Ray Crystal Structures of t-Bu3Ga. Sb(SiMe3)3, T-Bu2GaSb(SiMe3)2, and t-Bu2GaSb(SiMe3)Ga(t-Bu)2Cl, The first Example of a Gallium-Antimony Mixed-Bridge Compound

National Research Council Canada - National Science Library

Wells, Richard

1997-01-01

...:1 equilibration of t-Bu2GaCl with 2. These new gallium-antimony compounds have been characterized through multinuclear solution NMR spectroscopy, partial elemental analysis, and single-crystal X-ray structural analysis...

Stability of [MeBu3N][Tf2N] under gamma irradiation

International Nuclear Information System (INIS)

Bosse, Emilie; Berthon, Laurence; Zorz, Nicole; Monget, Julie; Berthon, Claude; Bisel, Isabelle; Legand, Solene; Moisy, Philippe

2008-01-01

The stability of the ionic liquid [MeBu 3 N][Tf 2 N], dry or after contact with water (where [MeBu 3 N] + is the methyl-tributyl-ammonium cation and [Tf 2 N] - is the bistriflimide anion), was studied under 137 Cs gamma irradiation in argon and in air. In a quantitative study with an absorbed dose of 2 MGy this ionic liquid was highly stable regardless of the radiolysis conditions. The radiolytic disappearance yields determined by ESI-MS were -0.38 and -0.25 μmol*J -1 for the cation and anion, respectively. ESI-MS, NMR, and liquid chromatography coupled with ESI-MS identified a large number of degradation products in very small quantities for the same dose. The cation radicals were formed by the loss of a Bu . group, the Me . group, or two H . atoms to form a double bond with the butyl chain. Radiolysis of the anion produced mainly F . and CF 3 . radicals. The anion radicals recombined with the cation to form a wide range of secondary degradation products regardless of the radiolysis conditions. (authors)

İtibar Yönetimi Açışından Yeşil Pazarlama: Örnek Olay İncelemesi / Green Marketing in Terms of Reputation Management: A Case Study

Directory of Open Access Journals (Sweden)

Samet Kavoğlu

2012-12-01

Full Text Available 21.yy modern işletmecilik mantığı çerçevesinde üretimin sorun olmaktan çıktığı, işletmeler için en önemli sıkıntının pazarlama faaliyetleri kapsamında yaşandığı düşünüldüğünde, alana dair çok sayıda yenilikçi fikrin ortaya çıkması oldukça normaldir. Bu fikri akımlar içerisinde yer alan, çalışma kapsamında incelenecek yeşil pazarlama uygulamalarını, diğerlerinden ayıran başlıca özellik pazarlama karması içerisinde yer alan tutundurma faaliyetlerinin her bir faktörüyle ilişkilendirilebilir olmasıdır. Çalışmanın sınırlarını çizebilmek ve derinlemesine araştırma olanağını arttırmak adına araştırma kapsamında yeşil pazarlamanın, tutundurma faaliyetlerinden halkla ilişkilerin, itibar yönetimi fonksiyonuyla olan ilişkisi, ödüllü bir proje olan “Unilever Sürdürülebilir Yaşam Planı” örneği üzerinden incelenmiştir. Çalışmanın sonunda, kuruluşun paydaşları nezdinde itibarını arttırmak gayesiyle hayata geçirilen yeşil pazarlama temalı, küresel ölçekli projenin hedefleri açısından genel değerlendirmesi yapılmıştır. Green Marketing in Terms of Reputation Management: A Case Study When it is taken into account that the production is no longer a problem within the framework of the modern business management logic of the 21st century and the primary difficulty is experienced by the businesses within the scope of the marketing activities, it is natural that a great number of innovative ideas emerge concerning the field. The main characteristic which distinguishes the practices of the green marketing which is in these streams of ideas and which will be examined within the scope of study from others is that they can be associated with each factor of promotional activities in the marketing mix. To be able to draw the lines of the study and to increase the possibility of the in-depth research, within the scope of the research, the relationship of

“PESTEL Analizi” ile Türkiye-Almanya Ekonomik İlişkilerinin İncelenmesi

OpenAIRE

AKÇA, Hasan; ŞAHİN, Levent; KAYA, Zekayi

2016-01-01

Bu çalışmanın amacı; Türkiye ve Almanya arasındaki ekonomik ilişkileri PESTEL Analizi ile irdelemektir. Çalışmada ikincil veriler (1924-2015) kullanılmıştır. PESTEL Analizinden elde edilen bazı sonuçlar şu şekilde özetlenebilir. Almanya bir taraftan gelecekte enerji darboğazı çekmemek için enerji koridorunda bulunan Türkiye ile ilişkileri olumlu yönde tutmaya çalışırken; diğer yandan Türkiye’nin AB’ye üyeliğine mesafeli durmaktadır. 1954-2015/Ağustos döneminde Türkiye’ye yatırım yapan toplam ...

Dispersive Sachdev-Ye-Kitaev model: Band structure and quantum chaos

Science.gov (United States)

Zhang, Pengfei

2017-11-01

The Sachdev-Ye-Kitaev (SYK) model is a concrete model for a non-Fermi liquid with maximally chaotic behavior in (0 +1 ) dimensions. In order to gain some insights into real materials in higher dimensions where fermions could hop between different sites, here we consider coupling a SYK lattice by constant hopping. We call this the dispersive SYK model. Focusing on (1 +1 ) -dimensional homogeneous hopping, by either tuning the temperature or the relative strength of the random interaction (hopping) and constant hopping, we find a crossover between a dispersive metal to an incoherent metal, where the dynamic exponent z changes from 1 to ∞ . We study the crossover by calculating the spectral function, charge density correlator, and the Lyapunov exponent. We further find the Lyapunov exponent becomes larger when the chemical potential is tuned to approach a van Hove singularity because of the large density of states near the Fermi surface. The effect of the topological nontrivial bands is also discussed.

The Influence of Romanticism on Mirzade-ye-eshgi’s Artistic Products

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Fatemeh Moddaresi

2012-11-01

Full Text Available Abstract Romanticism is a literarily movement which in last years of 18 the century , derived from England and changed to literally school in 19 century reaching most of the European countries, western Europe and even Russia. This school has deeply in flounced on different aspects of literature in different parts of the world. Romanticism school pierced into Iranian literature, when Iranian poets and writers got introduced with western literature. “ mirzade-ye-eshgi” is one of those poets who we can cleanly see the effects of romanticism school in his poems, since the value of this literarily products owes to romanticism school elements. Revolutionary, creativity, Retiring idealism flash backs to traditional literarily forms national emotions nostalgia creating atmospheres full of sadness and showing sympathy toward the poor, are ports of romanticism school in fluencies on his poems.

Stability of [MeBu3N][Tf2N] under gamma irradiation

International Nuclear Information System (INIS)

Bosse, E.; Berthon, L.; Zorz, N.; Monget, J.; Berthon, C.; Bisel, I.; Legand, S.; Moisy, P.

2008-01-01

The stability of the ionic liquid [MeBu 3 N][Tf 2 N], dry or after contact with water (where [MeBu 3 N] + is the methyl-tributyl-ammonium cation and [Tf 2 N] - is the bistriflimide anion), was studied under 137 Cs gamma irradiation in argon and in air. In a quantitative study with an absorbed dose of 2 MGy this ionic liquid was highly stable regardless of the radiolysis conditions. The radiolytic disappearance yields determined by ESI-MS were -0.38 and -0.25 μmolJ -1 for the cation and anion, respectively. ESI-MS, NMR, and liquid chromatography coupled with ESI-MS identified a large number of degradation products in very small quantities for the same dose. The cation radicals were formed by the loss of a Bu-radical group, the Me-radical group, or two H-radical atoms to form a double bond with the butyl chain. Radiolysis of the anion produced mainly F-radical and CF 3 -radicals. The anion radicals recombined with the cation to form a wide range of secondary degradation products regardless of the radiolysis conditions. (authors)

The pharmacokinetics and safety of twice daily i.v. BU during conditioning in pediatric allo-SCT recipients.

Science.gov (United States)

Le Gall, J B; Milone, M C; Waxman, I M; Shaw, L M; Harrison, L; Duffy, D; van de Ven, C; Militano, O; Geyer, M B; Morris, E; Bhatia, M; Satwani, P; George, D; Garvin, J H; Bradley, M B; Schwartz, J; Baxter-Lowe, L A; Cairo, M S

2013-01-01

Intravenous BU divided four times daily (q6 h) has been shown to be safe and effective in pediatric allo-SCT recipients. Though less frequent dosing is desirable, pharmacokinetic (PK) data on twice daily (q12 h) i.v. BU administration in pediatric allo-SCT recipients is limited. We prospectively examined the PK results in a cohort of pediatric allo-SCT recipients receiving i.v. BU q12 h as part of conditioning before allo-SCT. BU levels were obtained after the first dose of conditioning. PK parameter analysis (n=49) yielded the following 95% confidence intervals (CI₉₅): weight-normalized volume of distribution: 0.65-0.73 L/kg; t(1/2): 122-147 min; weight-normalized clearance (CL(n)): 3.4-4.3 mL/min/kg; and area under the curve: 1835-2180 mmol × min/L. From these results, a steady state concentration was calculated with CI₉₅ between 628-746 ng/mL. Comparison between recipients ≤4 vs >4 years old revealed significant differences in t(1/2) (mean: 115 vs 146 min, P=0.008) and CL(n) (mean: 4.4 vs 3.5 mL/min/kg, P=0.038). Intravenous BU q12 h had a comparable PK to i.v. BU q6 h PK seen in the literature, and in pediatric allo-SCT recipients, is a feasible, attractive alternative to i.v. q6h dosing.

Ta rık Buğra’s Novels Based o n Novel A n alysing Method a nd Nationalism Theme i n Tarık Buğra’s Novels

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Yıldıray BULUT

2015-07-01

Full Text Available In our study we try to analyse town based novelist Tarık Buğra’s novels in a ge neral point of wiev. We prefer P rof. Dr. Nurullah Çetin’s “Roman analysing methods” while conducting mentioned study. So, we may reach a general idea about what the novelist try to tell in his novels, what he aims and what kind of results he has. Buğra owns 23 novels totally. Ten of them are printed as boks. The y are listed chronically like: Yalnızlar (1948, Siyah Kehribar (1955, Küçük Ağa (1963 – later as “küçük ağa ankarada, nowadays brougth together as a one book - İbiş’in Rüyası (1970, Firavun İmanı (1978, Gençliğim Eyvah (1979, Dönemeçte (1980, Yağmur Beklerken (1989, Osmancık (1983. Nine of them are narrated by divine observer, and the other one is by subject - observer.in divine - observer novels, the novelist is dominant in the novels and owns an olympic point of view, but in the subject - observer narr ator novels, the subject experiences all the events. Subject - observer narrator novel is Siyah Kehribar, but in some parts, it is seen that divine - observer narrator is used. To the question that in Buğra’s novels, which themes are mentioned, we can sat that the loneliness of humanity, development of characteristic by the effect of society, efforts of the youth for showing themselves, big problems leading to success, a person’s characteristic change and his hero activities, love worhts, holiness of the countr y. İn an overview, Buğra’s novels discuss. male - female relation, nationalism, national struggle, otoman empire history, historical roots, politics and political issues, youth and social corruptin. İn his novels that discuss national struggle, it should bu expressed that he does not handle the issue in a formal way, but he talks about the background. When the mentioned novels are studied about their ends, it is seen that they have surprising, tragical and open - ended ends, even in most novels all

UPMC's blueprint for BuILDing a high-value health care system.

Science.gov (United States)

Keyser, Donna; Kogan, Jane; McGowan, Marion; Peele, Pamela; Holder, Diane; Shrank, William

2018-03-30

National-level demonstration projects and real-world studies continue to inform health care transformation efforts and catalyze implementation of value-based service delivery and payment models, though evidence generation and diffusion of learnings often occurs at a relatively slow pace. Rapid-cycle learning models, however, can help individual organizations to more quickly adapt health care innovations to meet the challenges and demands of a rapidly changing health care landscape. Integrated delivery and financing systems (IDFSs) offer a unique platform for rapid-cycle learning and innovation. Since both the provider and payer benefit from delivering care that enhances the patient experience, improves quality, and reduces cost, incentives are aligned to experiment with value-based models, enhance learning about what works and why, and contribute to solutions that can accelerate transformation. In this article, we describe how the UPMC Insurance Services Division, as part of a large IDFS, uses its Business, Innovation, Learning, and Dissemination (BuILD) model to prioritize, design, test, and refine health care innovations and accelerate learning. We provide examples of how the BuILD model offers an approach for quickly assessing the impact and value of health care transformation efforts. Lessons learned through the BuILD process will offer insights and guidance for a wide range of stakeholders whether an IDFS or independent payer-provider collaborators. Copyright © 2018 Elsevier Inc. All rights reserved.

Scalp and Body Acupuncture for Treatment of Senile Insomnia-A Report of 83 Cases

Institute of Scientific and Technical Information of China (English)

卢泽强

2002-01-01

@@ The author has in recent years treated 83 cases of senile insomnia with scalp and body acupuncture. Meanwhile, 35 cases in the control group were treated with western and Chinese drugs. The therapeutic results in the treatment group were superior to that of nitrazapam and An Shen Bu Nao Ye (安神补脑液Sedative and Brain-invigorating Fluid) used in the control group. A report of the treatment follows.

Validation of the YuWell YE690A upper-arm blood pressure monitor, for clinic use and self-measurement, according to the European Society of Hypertension International Protocol revision 2010.

Science.gov (United States)

Chen, Qi; Lei, Lei; Li, Yan; Wang, Ji-Guang

2017-10-01

The present study aimed to evaluate the accuracy of the automated oscillometric upper-arm blood pressure monitor YuWell YE690A for blood pressure measurement according to the International Protocol of the European Society of Hypertension revision 2010. Systolic and diastolic blood pressures were measured sequentially in 33 adult Chinese (12 women, 44.2 years of mean age) using a mercury sphygmomanometer (two observers) and the YE690A device (one supervisor). A total of 99 pairs of comparisons were obtained from 33 participants for judgments in two parts with three grading phases. All the blood pressure requirements were fulfilled. The YuWell YE690A device achieved the targets in part 1 of the validation study. The number of absolute differences between device and observers within 5, 10, and 15 mmHg was 79/99, 96/99, and 97/99, respectively, for systolic blood pressure and 72/99, 95/99, and 98/99, respectively, for diastolic blood pressure. The device also fulfilled the criteria in part 2 of the validation study. Thirty-one and 25 participants for systolic and diastolic blood pressure, respectively, had at least two of the three device-observer differences within 5 mmHg (required ≥24). No participant for systolic and two participants for diastolic blood pressure had all the three device-observer comparisons greater than 5 mmHg. The YuWell blood pressure monitor YE690A has passed the requirements of the International Protocol revision 2010 and hence can be recommended for blood pressure measurement in adults.

Prevalence of antibodies against Bubaline herpesvirus (BuHV-1) among Mediterranean water buffalo (Bubalus bubalis) with implications in buffalo trade.

Science.gov (United States)

Caruso, C; Prato, R; Ingravalle, F; Vecchio, D; Sciarra, A; Ternavasio, M; Ceccarelli, L; Martucciello, A; Galiero, G; De Carlo, E; Masoero, L

2016-12-01

Both Bovine herpesvirus (BoHV-1) and Bubaline herpesvirus (BuHV-1) have been reported to cross the species barrier. Antibody seroconversion in glycoprotein E (gE) blocking ELISA during BuHV-1 infection has been documented. Recent diagnostic efforts have focused on the development and application of discriminatory tests to distinguish between infections with BoHV-1 and BuHV-1. To evaluate the impact and distribution of these two infections in water buffalo farms in two regions (Piedmont (n = 3) and Campania (n = 10), Italy) where infectious bovine rhinotracheitis control programs have been implemented. Sampling was carried out on 13 buffalo farms comprising 1089 animals using specific gE-indirect ELISA's test able to discriminate among BoHV-1 and BuHV-1 infections. 59.0% of animals reacted positive to ELISA (irrespective of whether BoHV-1 or BuHV-1 antigen was used) and 86.4% of these were reactive to BuHV-1 only, whereas 11.8% showed absorbance values for both antigens and were classified as inconclusive. There was a statistically significant age-related difference in BuHV-1 infection rates but not in overall individual (47% vs. 58%) or herd prevalence (100% vs. 90%) of infection between the two regions. The low percentage of sera reactive to BoHV-1 (1.8%, 12/643) indicates that BuHV-1 may be the main circulating alphaherpesvirus infection in Mediterranean water buffalo in the two study areas. Since Bubalus bubalis is included in Directive 64/432/EEC on animal health problems affecting intra-community trade in bovine animals, diagnostic testing with nonspecific ELISA for BoHV-1 infection in buffalo may yield false-positive reactions. This scenario could lead to economic losses and hamper buffalo trade and movement, particularly for reproduction purposes.

Balancing Rural and Urban Development: Applying Coordinated Urban–Rural Development (CURD Strategy to Achieve Sustainable Urbanisation in China

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Ling-Hin Li

2017-10-01

Full Text Available Land in rural China has been under a separate and closed management system for decades even after the urban land reform that started in the late 1980s. The blurred property rights over rural land have been hindering the rural welfare as surplus rural land in sub-urban areas cannot be circulated into more economic use without first being requisitioned by the state. This traditional conversion process creates a lot of problems, among them are the compensation standard as well as displacement of rural residents to the city, where they cannot find adequate welfare protection. The prolonged disparity in economic outcomes for rural and urban residents in China in the process of urbanisation has made the authority realise that land-based local finance is no longer an option. Coordinated Urban and Rural Development (CURD ideology arises to set a level playing field by giving the rural residents comparable welfare status as their urban counterparts’ one. The CURD ideology is basically linked to the strategic development of the three main issues in the rural area of China, or in the Chinese terminology: San Nong. These three issues are rural villages, rural enterprises and rural farmers (nong cun, nong ye, nong min. CURD ideology is to preserve the livelihood of rural villages, facilitate and promote rural enterprises and increase the living standard of rural farmers. Most importantly, however, CURD policy package bestows rural residents with property rights over their farmland so that they could sub-co1ntract the user-rights to other urban commercial entities for higher benefits. While CURD policies are applied in a lot of different regions in China including Chongqing in the West, Qingdao in the North, Zhongshan in the South and Wuhan in the middle, we focus our examination in Chengdu as the Chengdu model has been widely documented and highly regarded as the most successful model in implementing the CURD strategies. From our case study, we find that

Aluminum triiodide induced complexation and structural rearrangement of the hexaphospha-pentaprismane cage, P6C4tBu4

International Nuclear Information System (INIS)

Al-Ktaifani, M. M.

2009-01-01

Treatment of P 6 C 4 t Bu 4 with the Lewis acid AlI 3 in toluene at room temperature unexpectedly results in a structural rearrangement affording the ionic complex [P 6 C 4 t Bu 4 H][AlI 4 ] which was fully characterized by multinuclear NMR spectroscopy and a single crystal X-ray diffraction study. Supportive evidence that the reaction might involve a simple intermediate Lewis acid-base adduct [AlI 3 (η 1 -P 6 C 4 t Bu 4 )] came from the isolation on one occasion of small number of crystals of the bis-Al adduct [(AlI)μ-(P 6 C 4 t Bu 4 )(AlI 3 )], whose molecular structure was also confirmed by a single crystal X-ray diffraction study. (author)

Occurrence of the Spotted Sea Hare Aplysia dactylomela (Rang 1828, Aplysiidae in the Yeşilovacık Bay, Norteastern Mediterranean Coast of Turkey

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Deniz Ayas

2017-10-01

Full Text Available The first record of the A. dactylomela from the Mediterranean Sea, in the Strait of Sicily waters was reported in 2002 (Trainito, 2003. Some reports of the A. dactylomela are given in the Mediterranean Sea in Table 1. A specimen of spotted sea hare was seen in a rock pool which was covered with algea. It was first recorded from Yeşilovacık Bay in 2017. Previous record of the species was noted in the Hatay coast of Turkey (Çinar et al. 2006. The present rapid communication reported the first record of A. dactylomela from the Yeşilovacık Bay. One specimen of A. dactylomela was photographed at the infralittoral zone of the Bay on 26 March, 2017, at a depth of 1 m in a rock pool togetter with Padina pavonica (Linnaeus and other algea.

Prokrastinācijas saistība ar mācību motivāciju studentiem

OpenAIRE

Rauska, Rihards

2017-01-01

Bakalaura darba tēma “Prokrastinācijas saistība ar mācību motivāciju studentu vidū”. Darbā analizēta teorētiskā literatūra par motivāciju, mācību motivāciju un prokrastināciju. Bakalaura darba mērķis mācību motivācija un prokrastinācijas savstarpējās saistības izpēte un analīze. Pētījumā piedalījušies 50 respondentu vecumā no 19 – 40 gadu vecumam. Bakalaura darba pētījuma veikšanai izmantotas divas metodes: 1.Prokrastinācijas aptauja, (Procrastination scale Lay,1986), Latvijā aptauju adaptēj...

Bulgur Üretiminin Buğdayların bazı Kimyasal Özelliklerinde Meydana Getirdiği Değişiklikler

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Özen Özboy

2015-02-01

Full Text Available Bu çalışmada bulgur üretiminin buğdayların protein, kül, b-karaten ve Lovibond kolorimetre ile belirlenen R (kırmızılık, Y (sarılık, O (opaklık değerlerinde meydana getirdiği değişiklikler incelenmiştir. Araştırmada 29 adet saf buğday örneği (23 adet durum ve 6 adet ekmeklik kullanılmıştır. Buğdaydan bulgura geçerken protein miktarındaki bir değişiklik meydana gelmemiş, kül miktarında ise önemsiz derecede bir azalma tespit edilmiştir. Buğdayın bulgura dönüştürülmesi ile b-karoten miktarında düşüş olduğu saptanmıştır. Lovibond  kolorimetre ile tespit edilen R, Y, O değerlerinde de bir azalma olmuştur. Bu çalışmada makarnalık ve ekmeklik buğdaylarla, onlardan hazırlanan bulgurlara ait protein, b-karoten ve kül değerleri (p<0.01 arasında önemli ilişki olduğu belirlenmiştir. Ayrıca, buğday unu, buğday kırması ve bulgura ait kül değerleri ile Lovibond kolorimetre ile belirlenen R ve Y değerleri arasında önemli bir düzeyde negatif bir ilişki olduğu belirlenmiştir (p<0.05.

Foreign Body Inhalation: A Review of Patients at the Korle Bu ...

African Journals Online (AJOL)

BACKGROUND: Foreign body inhalation, a surgical emergency requiring prompt management to avoid morbidity and mortality , poses a diagnostic and management challenge to otolaryngologists. OBJECTIVE: To assess the pattern of foreign body inhalation at the ENT Unit Korle Bu Teaching Hospital Accra, Ghana.

Buğdayın Tiamin ve Riboflavin Miktarı Üzerine Azotlu Gübre Uygulamasının Etkisi

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Emine Bildik

2015-02-01

Full Text Available Bu çalışmada değişik dozda azotlu gübre uygulamasının buğdayın tiamin, riboflavin, protein ve kül miktarlarına etkisi araştırılmıştır. Bu amaçla azotlu gübre, dekara 0.3, 6.9 ve 12 kg azot hesabıyla Amonyum Nitrat olarak tamamı ekim sırasında uygulanmıştır. İstatistiksel analiz sonuçlarına göre; buğdayın protein, kül ve tiamin miktarı üzerine azot uygulamasının etkisi %1 seviyesinde önemli bulunmuştur. Azotlu gübre uygulaması buğdayın protein miktarını artırmış, kül miktarını azaltmıştır. Azotlu gübre uygulaması buğdayın tiamin ve riboflavin miktarını da etkilemiş ve özellikle tiamin miktarını önemli düzeyde artırmıştır. Buğdayın protein miktarı ile tiamin miktarı arasında önemli ve pozitif yönde %1 düzeyinde korelasyonlar saptanmıştır. Kül miktarı ile tiamin miktarı arasında da pozitif yönde bir ilişki bulunmuştur.

High-throughput LC-MS method for the rapid characterization of multiple chemical constituents and metabolites of Da-Bu-Yin-Wan.

Science.gov (United States)

Li, Xianna; Sun, Hui; Zhang, Aihua; Liu, Zhidong; Zou, Di; Song, Yanhua; Liu, Liang; Wang, Xijun

2017-11-01

Traditional Chinese medicine is the clinical experience accumulated by Chinese people against diseases. Da-Bu-Yin-Wan is a famous traditional Chinese medicine formula consisting of Phellodendri amurensis Rupr., Anemarrhenae asphodeloides Bge., Radix Rehmanniae Preparata and Chinemys reevesii. In this study, ultra high performance liquid chromatography with electrospray ionization quadrupole time-of-flight high-definition mass spectrometry with the control software of Masslynx (V4.1) was established for comprehensive screening and identification of the chemical constituents and serum metabolites of Da-Bu-Yin-Wan in vivo and in vitro. Consequently, 70 peaks in the methanol extract from Da-Bu-Yin-Wan and 38 peaks absorbed into rat blood were characterized. The 70 constituents in vitro included alkaloids, flavonoids, polysaccharide, limonoids, flavonoid, etc. And the 38 constituents consist of 22 absorbed prototypes and 16 metabolites of Da-Bu-Yin-Wan absorbed in vivo. We fully clarified the chemical constituents of Da-Bu-Yin-Wan and provided a scientific strategy for the screening and characterization of the chemical constituents and metabolites of traditional Chinese medicine in vitro and in vivo. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Zamurowana niewiasta, Odyseusz i Bułgarska Wielkanoc. Tonczo Żeczew w poszukiwaniu mitu konserwatywnego

Directory of Open Access Journals (Sweden)

Grażyna Szwat-Gyłybowa

2017-10-01

Full Text Available The immured woman, Odysseus and Bulgarian Easter: Toncho Zhechev and the quest for a conservative myth This article reflects on Bulgarian Easter, or Bulgarian Passions, a 1975 book by the Bulgarian humanist Toncho Zhechev, once regarded in Communist Bulgaria as a call for a return to traditional values. Zhechev’s quasi-conservative ideological turn (which in formal terms ran counter to the precepts of Marxist ideology was based, among other things, on a complex and richly layered reinterpretation of Izvorat na belonogata, a poem by Petko R. Slaveykov (The Spring of the White-Legged Girl, 1873, and on its revitalisation of the myths of the immured woman and of Odysseus. The way Zhechev positively reinvented a manufactured archaic tradition as a mainstay of primeval wisdom and mysticism offers an interesting testimony to the quest for a concept of “integral traditionalism” in a form that was reconcilable with the progressism of the Zhivkov era.   Zamurowana niewiasta, Odyseusz i Bułgarska Wielkanoc. Tonczo Żeczew w poszukiwaniu mitu konserwatywnego W artykule podejmuję refleksję nad książką bułgarskiego humanisty Tonczo Żeczewa Bułgarska Wielkanoc albo namiętności bułgarskie (1975, która w komunistycznej Bułgarii zdobyła status dzieła głoszącego ideę powrotu do wartości tradycyjnych. Dokonany przez niego (formalnie rzecz biorąc – wbrew ideologii marksistowskiej quasi-konserwatywny zwrot światopoglądowy oparty został m.in. na dosyć złożonej, wielowarstwowej reinterpretacji poematu Petka R. Sławejkowa Źródło Białonogiej (1873 oraz na rewitalizacji mitów zamurowanej niewiasty oraz Odyseusza. Dowartościowanie przez Żeczewa wynalezionej tradycji archaicznej jako ostoi pierwotnej mądrości i mistyki stanowi interesujące świadectwo poszukiwań takiej idei „tradycjonalizmu integralnego”, która byłaby do pogodzenia z progresizmem epoki żiwkowskiej.

Stability of [MeBu{sub 3}N][Tf{sub 2}N] under gamma irradiation

Energy Technology Data Exchange (ETDEWEB)

Bosse, Emilie; Berthon, Laurence; Zorz, Nicole; Monget, Julie; Berthon, Claude; Bisel, Isabelle; Legand, Solene; Moisy, Philippe [CEA Marcoule, DCRP/SCPS, BP 17171, 30207 Bagnols sur Ceze Cedex (France)

2008-07-01

The stability of the ionic liquid [MeBu{sub 3}N][Tf{sub 2}N], dry or after contact with water (where [MeBu{sub 3}N]{sup +} is the methyl-tributyl-ammonium cation and [Tf{sub 2}N]{sup -} is the bistriflimide anion), was studied under {sup 137}Cs gamma irradiation in argon and in air. In a quantitative study with an absorbed dose of 2 MGy this ionic liquid was highly stable regardless of the radiolysis conditions. The radiolytic disappearance yields determined by ESI-MS were -0.38 and -0.25 {mu}mol*J{sup -1} for the cation and anion, respectively. ESI-MS, NMR, and liquid chromatography coupled with ESI-MS identified a large number of degradation products in very small quantities for the same dose. The cation radicals were formed by the loss of a Bu{sup .} group, the Me{sup .} group, or two H{sup .} atoms to form a double bond with the butyl chain. Radiolysis of the anion produced mainly F{sup .} and CF{sub 3}{sup .} radicals. The anion radicals recombined with the cation to form a wide range of secondary degradation products regardless of the radiolysis conditions. (authors)

Effects of Supported ( n BuCp) 2 ZrCl 2 Catalyst Active-Center Distribution on Ethylene–1-Hexene Copolymer Backbone Heterogeneity and Thermal Behaviors

KAUST Repository

Atiqullah, Muhammad; Anantawaraskul, Siripon; Emwas, Abdul Hamid M; Al-Harthi, Mamdouh A.; Hussain, Ikram; Ul-Hamid, Anwar; Hossaen, Anwar

2013-01-01

Two catalysts, denoted as catalyst 1 [silica/MAO/(nBuCp) 2ZrCl2] and catalyst 2 [silica/nBuSnCl 3/MAO/(nBuCp)2ZrCl2] were synthesized and subsequently used to prepare, without separate feeding of methylaluminoxane (MAO), ethylene homopolymer 1

Genetic analysis in maize foundation parents with mapping population and testcross population: Ye478 carried more favorable alleles and using QTL information could improve foundation parents

Directory of Open Access Journals (Sweden)

Yinghong Liu

2016-09-01

Full Text Available The development of maize foundation parents is an important part of genetics and breeding research, and applying new genetic information to produce foundation parents has been challenging. In this study, we focused on quantitative trait loci (QTLs and general combining ability (GCA of Ye478, a widely used foundation parent in China. We developed three sets of populations for QTL mapping and to analyze the GCA for some agronomic traits. The assessment of 15 traits resulted in the detection of 251 QTLs in six tested environments, with 119 QTLs identified through a joint analysis across all environments. Further analyses revealed that most favorable alleles for plant type-related traits were from Ye478, and more than half of the favorable alleles for yield-related traits were from R08, another foundation parent used in southwestern China, suggesting that different types of foundation parents carried different favorable alleles. We observed that the GCA for most traits (e.g., plant height and 100-kernel weight was maintained in the inbred lines descended from the foundation parents. Additionally, the continuous improvement in the GCA of the descendants of the foundation parents was consistent with the main trend in maize breeding programs. We identified three significant genomic regions that were highly conserved in three Ye478 descendants, including the stable QTL for plant height. The GCA for the traits in the F7 generation revealed that the QTLs for the given traits per se were affected by additive effects in the same way in different populations.

Darbinieku apmierinātību ietekmējošo faktoru novērtējums uzņēmumā AS „Cēsu alus”.

OpenAIRE

Petroviča, Lelde

2013-01-01

Maģistra darba temats ir „Darbinieku apmierinātību ietekmējošo faktoru novērtējums uzņēmumā AS „Cēsu alus””. Darba mērķis: izpētīt darbinieku apmierinātību ar darbu ietekmējošos faktorus uzņēmumā AS „Cēsu alus” un izstrādāt priekšlikumus apmierinātības ar darbu paaugstināšanai. Darba pirmajā daļā tiek aplūkoti teorētiskie aspekti par apmierinātību ar darbu būtību, uzmanību vēršot, apmierinātības ietekmei uz uzņēmuma darbību un to ietekmējošiem faktoriem. Otrajā daļā ar interviju palīdzību tie...

Substitution and Redox Chemistry of [Bu(4)N](2)[Ta(6)Cl(12)(OSO(2)CF(3))(6)].

Science.gov (United States)

Prokopuk, Nicholas; Kennedy, Vance O.; Stern, Charlotte L.; Shriver, Duward F.

1998-09-21

Two sequential electrochemical reductions occur for the cluster anion [Ta(6)Cl(12)(OSO(2)CF(3))(6)](2)(-) at 0.89 and 0.29 V vs Ag/AgCl, with the generation [Ta(6)Cl(12)(OSO(2)CF(3))(6)](3)(-) and [Ta(6)Cl(12)(OSO(2)CF(3))(6)](4)(-). Chemical reduction of [Ta(6)Cl(12)(OSO(2)CF(3))(6)](2)(-) by ferrocene produces [Ta(6)Cl(12)(OSO(2)CF(3))(6)](3)(-) with the concomitant shift of the nu(SO(2)) stretch from 1002 to 1018 cm(-)(1). Reaction of [Bu(4)N](2)[Ta(6)Cl(12)(OSO(2)CF(3))(6)] (1) with [Bu(4)N]X (X = Cl, Br, I, NCS) occurs by reduction and substitution, yielding [Bu(4)N](3)[Ta(6)Cl(12)X(6)], where the clusters with X = Br, I, and NCS are new. Spectroscopic (IR and UV-vis) evidence indicates that the reduced cluster core {Ta(6)Cl(12)}(2+) is produced in reaction mixtures of 1 with the halide and pseudohalide ions. Concomitant substitution of the triflate ligands of 1 by X(-) occurs and the rates for the overall reduction and substitution increase in the order X(-) = Cl(-) < Br(-) < NCS(-) < I(-) < CN(-). Reduction of 1 with ferrocene followed by addition of [Bu(4)N]O(2)CCH(3) produces the new cluster [Ta(6)Cl(12)(O(2)CCH(3))(6)](3)(-) isolated as the tetrabutylammonium salt. Cyclic voltammetry and UV-vis spectroscopy on the new clusters [Bu(4)N](3)[Ta(6)Cl(12)X(6)] (X = Br, I, NCS, and O(2)CCH(3)) are reported. Crystal data for [Bu(4)N](3)[Ta(6)Cl(12)(NCS)(6)].CH(2)Cl(2): monoclinic, space group, P2(1)/c (No. 14); a = 25.855(6) Å, b = 21.843(6) Å, c = 16.423(3) Å; beta = 100.03(2) degrees; V = 9133(3) Å(3); Z = 4.

One-step Conversion of Levulinic Acid to Succinic Acid Using I2/t-BuOK System: The Iodoform Reaction Revisited.

Science.gov (United States)

Kawasumi, Ryosuke; Narita, Shodai; Miyamoto, Kazunori; Tominaga, Ken-Ichi; Takita, Ryo; Uchiyama, Masanobu

2017-12-21

The iodoform reaction has long been used as a qualitative test for acetyl and/or ethanol units in organic molecules. However, its synthetic applications are quite limited. Here, we describe a tuned iodoform reaction for oxidative demethylation reaction with I 2 and t-BuOK in t-BuOH, in which in situ-generated t-BuOI serves as the chemoselective iodinating agent. This system enables one-step conversion of levulinic acid to succinic acid, a major four-carbon chemical feedstock. This oxidative demethylation is also applicable to other compounds containing an acetyl group/ethanol unit, affording the corresponding carboxylic acids in a selective manner.

RCRA Part A permit characterization plan for the U-2bu subsidence crater. Revision 1

International Nuclear Information System (INIS)

1998-04-01

This plan presents the characterization strategy for Corrective Action Unit (CAU) 109, U-2bu Subsidence Crater (referred to as U-2bu) in Area 2 at the Nevada Test Site (NTS). The objective of the planned activities is to obtain sufficient characterization data for the crater soils and observed wastes under the conditions of the current Resource Conservation and Recovery Act (RCRA) Part A permit. The scope of the characterization plan includes collecting surface and subsurface soil samples with hand augers and for the purpose of site characterization. The sampling strategy is to characterize the study area soils and look for RCRA constituents. Observable waste soils and surrounding crater soils will be analyzed and evaluated according to RCRA closure criteria. Because of the status of the crater a RCRA Part A permit site, acquired radionuclide analyses will only be evaluated in regards to the health and safety of site workers and the disposition of wastes generated during site characterization. The U-2bu Subsidence Crater was created in 1971 by a Lawrence Livermore National Laboratory underground nuclear test, event name Miniata, and was used as a land-disposal unit for radioactive and hazardous waste from 1973 to 1988

Lowering of the YE+3 endcap disc on 30th November

CERN Multimedia

Max Brice, CERN

2006-01-01

Gigantic disc of CMS detector travels 100 m under the Earth It's an amazing engineering challenge - the lowering of the first tremendous endcap disc, known as YE+3, of the CMS particle detector slowly and carefully 100 m underground into the experimental cavern. The disc is one of 15 large pieces to make the grand descent. It's a uniquely shaped slice, 16 m high, about 50 cm thick and weighing 400 tonnes. The solid steel structure of the disc forms part of the magnet return yoke and is equipped on both sides with muon chambers. A special gantry crane will lower the element, with just 20 cm of leeway between the edges of the detector and the walls of the shaft. CMS is one of the four main experiments that will take data at the world's highest energy particle accelerator, CERN's Large Hadron Collider (LHC). The LHC is a 27 km circular ring 100 m underground. The CMS detector weighs a total of 12 500 tonnes and is constructed on the surface. Once all of the pieces are fully equipped, lowered underground and re-t...

On the relationship between LTL normal forms and Büchi automata

DEFF Research Database (Denmark)

Li, Jianwen; Pu, Geguang; Zhang, Lijun

2013-01-01

In this paper, we revisit the problem of translating LTL formulas to Büchi automata. We first translate the given LTL formula into a special disjuctive-normal form (DNF). The formula will be part of the state, and its DNF normal form specifies the atomic properties that should hold immediately...

Mācību video materiālu izstrāde tēmas „Elektrība” apguvei vidusskolas fizikā

OpenAIRE

Kravis, Kārlis

2013-01-01

Diplomdarbā „Mācību video materiālu izstrāde tēmas „Elektrība” apguvei vidusskolas fizikā” ir izveidoti, aprobēti un ekspertu izvērtēti 15 mācību video. Tēma „Elektrība”, it īpaši elektrostatikas jautājumi, ir abstrakti skolēna izpratnei, jo fizikālie procesi notiek mikropasaules līmenī. Līdz ar sabiedrības pieprasījumu par mācību materiālu digitalizāciju un esošo materiālu piedāvājumu ir aktualizējies jautājums, kā kvalitatīvus digitālos materiālus izmantot mācību procesā skolēnu zināšanu un...

Comparative pharmacokinetics of swertiamarin in rats after oral administration of swertiamarin alone, Qing Ye Dan tablets and co-administration of swertiamarin and oleanolic acid.

Science.gov (United States)

Xu, Gui-li; Li, Hong-liang; He, Jian-chang; Feng, En-fu; Shi, Pan-pan; Liu, Yue-qiong; Liu, Chang-xiao

2013-08-26

Qing Ye Dan is a well-known herbal drug that is widely used to treat viral hepatitis in the Yi and Hani minority regions in the Yunnan province of China. An LC-MS/MS method was developed to determine the levels of swertiamarin in rat plasma. Swertiamarin and naringin (internal standard, IS) were extracted from rat plasma using solid-phase extraction (SPE) to purify the samples. The pharmacokinetics of the following different administration methods of swertiamarin in rats were studied: oral administration of swertiamarin alone, a Qing Ye Dan tablet (QYDT) and co-administration of swertiamarin and oleanolic acid, with each method delivering approximately 20mg/kg of swertiamarin. Non-compartmental pharmacokinetic profiles were constructed by using the software DAS (version 2.1.1), and the pharmacokinetic parameters were compared using an unpaired Student's t-test. The results showed that the pharmacokinetic parameters Cmax, AUC0-∞, Vz/F and CLz/F were significantly different (P<0.05) among the three types of swertiamarin administration. The data indicate that oleanolic acid and the other ingredients present in QYDT could affect the pharmacokinetic behaviour of swertiamarin in rats. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

On the inversion of the 1 Bu and 2 Ag electronic states in α,ω-diphenylpolyenes

Science.gov (United States)

Catalán, J.

2003-07-01

An alternative model to that of the inversion of the states 1Bu and 2Ag is proposed for interpreting the photophysics of the α,ω-diphenylpolyenes. This model is based upon the existence of two chemical structures with Bu symmetry, which may be ascribed to the same excited electronic state 1Bu. One of the two chemical structures corresponds to the Franck-Condon structure with conjugated single and double bonds for the polyene chain, and another consists of a nearly equivalent series of partial double bonds along the polyene chain. The latter relaxed structure is consistent with the observation of high torsional energy barriers and low photoisomerization quantum yields for diphenylhexatriene in the singlet excited state manifold. Interestingly, such a simple quantum model as that of the particle in a one-dimensional box provides quite an accurate description of the absorption spectroscopic properties of these major compounds. This is partly the result of the most stable structures for these compounds being of the all-trans type; such structures increase in length as additional ethylene units are added, which makes them very similar to a one-dimensional box becoming increasingly longer.

The Influence of Romanticism on Mirzade-ye-eshgi’s Artistic Products

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Fatemeh Moddaresi

2012-10-01

Full Text Available  Abstract Romanticism is a literarily movement which in last years of 18 the century , derived from England and changed to literally school in 19 century reaching most of the European countries, western Europe and even Russia. This school has deeply in flounced on different aspects of literature in different parts of the world. Romanticism school pierced into Iranian literature, when Iranian poets and writers got introduced with western literature. “ mirzade-ye-eshgi” is one of those poets who we can cleanly see the effects of romanticism school in his poems, since the value of this literarily products owes to romanticism school elements. Revolutionary, creativity, Retiring idealism flash backs to traditional literarily forms national emotions nostalgia creating atmospheres full of sadness and showing sympathy toward the poor, are ports of romanticism school in fluencies on his poems.   Â

Kuulumatusest, prantsuse keeles : Buñuel, Villeneuve ja Audiard katusekinos / Tristan Priimägi

Index Scriptorium Estoniae

Priimägi, Tristan, 1976-

2011-01-01

Katusekino maikuu programmis on Luis Buñueli "Päevane kaunitar" ("Belle de jour", Prantsusmaa-Itaalia 1967), Denis Villeneuve "Põlenud" ("Incendies", Kanada-Prantsusmaa 2010) ja Jacques Audiard´i "Prohvet" ("Un prophète", Prantsusmaa-Itaalia 2009)

Klientu attiecību sociālās vadības ietekme uz klientu lojalitāti; sociālā tīkla Facebook piemērs

OpenAIRE

Avotiņa, Lelde

2015-01-01

Maģistra darba “Klientu attiecību sociālās vadības ietekme uz klientu lojalitāti; sociālā tīkla Facebook piemērs” mērķis ir noteikt un analizēt faktorus, kas ietekmē lojālo klientu piesaistīšanu un noturēšanu sociālo mediju vidē klientu attiecību sociālās vadības kontekstā. Maģistra darba pirmajā nodaļā tiek aplūkoti jautājumi, kas skar klientu lojalitāti, klientu attiecību vadību, klientu lomu sociālo mediju kontekstā un klientu attiecību sociālo vadību. Šī teorētiskā apkopojuma rezultātā...

Gemlik Çeşidi Salamura Zeytin Üretiminde Diffüzyon Katsayısının Belirlenmesi ve Farklı Tuz Derişiminin Laktik Asit ve İndirgen Şeker Üzerine Etkisi

Directory of Open Access Journals (Sweden)

Ömer Faruk Gamlı

2016-11-01

Full Text Available Bu çalışmada, farklı tuz derişimlerindeki (%8-14 salamuralar kullanılarak Osmaniye’de yetiştirilen Gemlik çeşidi yeşil ve siyah zeytinlerden sofralık, salamura zeytin üretimi gerçekleştirilmiştir. Salamuralardaki tuz konsantrasyonlarının artması ile birlikte yeşil zeytinlerde nem değerlerinin %45,23-54,90, siyah zeytinlerde %46,04-56,53 arasında değiştiği; yeşil zeytinlerde tuz miktarlarının %1,21-5,22 arasında, siyah zeytinlerde ise %2,32-5,57 arasında değiştiği belirlenmiştir. Artan tuz konsantrasyonlarına bağlı olarak yayılım katsayılarının da arttığı belirlenmiştir. Yeşil zeytinlerde yayılım katsayıları 4.38 × 10-8- 6,59 × 10-7 (m2s-1 arasında, siyah zeytinlerde ise 3,79 × 10-8 – 3,56 × 10-7 (m2s-1 arasında değişim göstermiştir. Yeşil siyah zeytinlerde laktik asit konsantrasyonlarının %0,43-0,45, siyah zeytinlerde ise %0,41-0.44 arasında değiştiği tespit edilmiştir. %10-12’ lik salamuralarda laktik asit oluşumunun diğerlerine oranla daha fazla olduğu belirlenmiştir. İndirgen şeker miktarlarının yeşil zeytinlerde olgunlaşmanın ilerlemesiyle birlikte %4,76-1,88, siyah zeytinlerde ise %4,89-2,01 arasında değişim gösterdiği görülmüştür.

Klientu attiecību pārvaldības sistēmas izveide autoservisam

OpenAIRE

Jaunzems, Ģirts

2012-01-01

Diplomdarba tēma ir Klientu attiecību pārvaldības sistēmas izveide autoservisam. Tā mērķis ir izstrādāt un ieviest pielāgotu klientu attiecību pārvaldības sistēmu nelielam autoservisam, tādējādi atvieglojot klientu un viņu darbības vēstures uzskaiti. Lai sasniegtu diplomdarba mērķi, darba autors izpētīja teorētiskos informācijas avotus, salīdzināja divas klientu pārvaldības sistēmas, kā arī izstrādāja sistēmu konkrētam uzņēmumam, veicot arī tās izmaksu analīzi. Diplomdarbā ir secināts, ...

Maximizing microscopy as a diagnostic tool in peripheral health centres of BU endemic areas in Ghana.

Science.gov (United States)

Owusu, Enid; Newman, Mercy Jemima; Akumwena, Amos; Ofosu-Appiah, Lawrence; Pluschke, Gerd

2015-09-01

Buruli ulcer (BU) disease, a skin condition caused by Mycobacterium ulcerans (M. ulcerans) is endemic in remote rural areas. Disease diagnosis on clinical basis alone can be misleading, requiring definitive diagnosis based on laboratory tests. Resource constraints in BU endemic areas make microscopy for the detection of acid fast bacilli (AFB) an important and useful method. It is rapid, user-friendly, convenient and cheap. Despite its usefulness, its performance is relatively low. This study investigated modifications of the current method aimed at improving its performance. Forty (IS) 2404 polymerase chain reactions (PCR) positive BU samples were processed by eight physical (centrifugation and overnight sedimentation) and chemical (phenol ammonium sulphate and sodium hypochlorite) modifications of the current direct method. Assessments were based on standard AFB evaluation coupled with in house criteria; positivity (P), clarity and contrast (C) release of bacilli from specimen (R). Overall AFB positivity rate was 64% (409/640). Each protocol had 80 smears. The percentage positivity (P) for the conventional method was 58% (46/80) smears. The highest positivity rate of 57/80 (%) was by protocol 7 (5% phenol in 4% ammonium sulphate (PhAS) and concentrated by overnight gravitational sedimentation). The least positivity rate at 35% (28/80) was by protocol 1 (smears from direct application of swab tips). The differences in performance between the two chemical tested; 5% phenol in 4% ammonium sulphate (PhAS) and 3.5% NaHOCl was significant (p0.05). This study concluded that BU samples treated with a solution of 5% phenol in 4% ammonium sulphate and concentrated by either centrifugation or overnight sedimentation is useful for maximizing AFB detection by bright field microscopy. This can be useful in rural health facilities with resource constraints. Copyright © 2015 Asian-African Society for Mycobacteriology. Published by Elsevier Ltd. All rights reserved.

Maximizing microscopy as a diagnostic tool in peripheral health centres of BU endemic areas in Ghana

Directory of Open Access Journals (Sweden)

Enid Owusu

2015-01-01

Full Text Available Background: Buruli ulcer (BU disease, a skin condition caused by Mycobacterium ulcerans (M. ulcerans is endemic in remote rural areas. Disease diagnosis on clinical basis alone can be misleading, requiring definitive diagnosis based on laboratory tests. Resource constraints in BU endemic areas make microscopy for the detection of acid fast bacilli (AFB an important and useful method. It is rapid, user-friendly, convenient and cheap. Despite its usefulness, its performance is relatively low. This study investigated modifications of the current method aimed at improving its performance. Forty (IS 2404 polymerase chain reactions (PCR positive BU samples were processed by eight physical (centrifugation and overnight sedimentation and chemical (phenol ammonium sulphate and sodium hypochlorite modifications of the current direct method. Assessments were based on standard AFB evaluation coupled with in house criteria; positivity (P, clarity and contrast (C release of bacilli from specimen (R. Overall AFB positivity rate was 64% (409/640. Each protocol had 80 smears. The percentage positivity (P for the conventional method was 58% (46/80 smears. The highest positivity rate of 57/80 (% was by protocol 7 (5% phenol in 4% ammonium sulphate (PhAS and concentrated by overnight gravitational sedimentation. The least positivity rate at 35% (28/80 was by protocol 1 (smears from direct application of swab tips. The differences in performance between the two chemical tested; 5% phenol in 4% ammonium sulphate (PhAS and 3.5% NaHOCl was significant (p 0.05. This study concluded that BU samples treated with a solution of 5% phenol in 4% ammonium sulphate and concentrated by either centrifugation or overnight sedimentation is useful for maximizing AFB detection by bright field microscopy. This can be useful in rural health facilities with resource constraints.

Informācijpratības un sadarbības prasmes attīstīšana ar WebQuest mācību modeli

OpenAIRE

Gulbis, Mārtiņš

2011-01-01

Informācijpratības un sadarbības prasmes attīstīšana ar WebQuest mācību modeli. Gulbis M., zinātniskais vadītājs Dr.chem.,. docents Logins J., kvalifikācijas darbs, 41 lappuses, 6 attēli, 7 tabulas, 2 pielikumi, 25 literatūras avoti. Latviešu valodā. WEBQUEST, PROJEKTA APRAKSTS, DARBA UZDEVUMI, SPIRTI, FENOLI, INFORMĀCIJPRATĪBA, SADARBĪBAS PRASMES. Darbā veikta literatūras izpēte par WebQuest mācību modeļa izmantošanu ķīmijas mācību procesā, lai attīstītu skolēnu informācijpratību un sa...

Lenguaje e identidad colectiva en Buñuel. Propaganda en el filme «España 1936» Language and Collective Identity in Buñuel. Propaganda in the Film «España 1936»

Directory of Open Access Journals (Sweden)

Francisco Javier Ruiz del Olmo

2010-10-01

Full Text Available En la memoria colectiva de los europeos, la Guerra Civil española ocupa un lugar destacado. El lenguaje cinematográfico y la representación fílmica de esa contienda forman un ámbito relevante en el que estudiar algunos rasgos de la matriz cultural europea. El presente trabajo selecciona parte de la producción fílmica de propaganda del gobierno republicano, en concreto los filmes de montaje supervisados por Luis Buñuel. Al inicio de la contienda el cineasta aragonés vuelve a París siguiendo las indicaciones del Ministerio español de Asuntos Exteriores para colaborar, en la embajada española en la capital francesa, en diversas labores de contraespionaje y propaganda. Entre ellas y principalmente, Buñuel se ocupa de reunir, organizar y montar diverso material fílmico prorrepublicano. A diferencia de otras producciones proyectadas en España, los filmes parisinos de propaganda republicana se caracterizaron, en términos generales, por estar dirigidas a públicos de distintos países europeos con el objetivo de romper la doctrina de no intervención en el conflicto y se inscriben dentro de las teorías y concepción de Buñuel sobre el documentalismo filmado, donde primaba lo reflexivo y los recursos psicológicos que motivaran a la acción o a la toma de conciencia individual. El presente texto se ocupa, en ese contexto, de la descripción y el análisis del lenguaje y las prácticas fílmicas en esos años. De todas ellas, el filme «España, 1936» (1937, es a la vez un ejemplo emblemático y singular.The Spanish Civil War occupies an important place in the European collective memory. The film language and depiction of that conflict provide an important platform from which to study certain features of the European cultural matrix. This paper examines propaganda films produced by the Republican government, especially those films produced under the supervision of Luis Buñuel, the Spanish surrealist filmmaker. At the start of the war

Kelîle Ve Dimne Hikâyelerinin Yaratımı Ve Aktarımı: Pança Tantra’dan Hümâyûn-Nâme’ye

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Tuncay BÜLBÜL

2017-12-01

ı Kelile ve Dimne hikâyeleri ismiyle anılmaya başlamıştır. Mukaffa’nın bu tercümesi Kelile ve Dimne hikâyelerinin dünya dillerine yayılmasında büyük rol oynamıştır. Kelile ve Dimne hikâyelerinin bir başka önemli tercümesi ise Hüseyin Vâiz-i Kâşifî’nin İbnü’l-Mukaffa’nın eserinden Farsçaya çevirdiği Envâr-ı Süheylî adlı eseridir. Bu eser, İbnü’l-Mukaffa’nın eserinden gerek kurgu ve gerekse hikâye sayısı bakımından büyük farklılıklar taşımaktadır. Türk edebiyatında ise Kelile ve Dimne hikâyeleri özellikle Doğu Türkçesiyle pek çok kez tercüme edilmiştir. Anadolu sahasında ise bilinen sadece iki tercümesi bulunmaktadır. Bunlardan birisi Kul Mes’ud tercümesi bir diğeri de Hüseyin Vâiz-i Kâşifî’nin Envâr-ı Süheylî adlı eserine dayanan Filibeli Alâaddîn Ali Çelebi’nin Hümâyûn-nâme adlı eseridir. Bu çalışmada, “sözlü kültür ortamı” kavramı etrafında ana hatlarıyla çizilen bir çerçeveden sonra Hint sözlü kültür ortamının bir ürünü olan Pança Tantra anlatmalarının tercüme marifetiyle dünyadaki farklı kültürlerde kat ettiği mesafe ortaya konmaya çalışılmıştır.

Competition between Chaotic and Nonchaotic Phases in a Quadratically Coupled Sachdev-Ye-Kitaev Model.

Science.gov (United States)

Chen, Xin; Fan, Ruihua; Chen, Yiming; Zhai, Hui; Zhang, Pengfei

2017-11-17

The Sachdev-Ye-Kitaev (SYK) model is a concrete solvable model to study non-Fermi liquid properties, holographic duality, and maximally chaotic behavior. In this work, we consider a generalization of the SYK model that contains two SYK models with a different number of Majorana modes coupled by quadratic terms. This model is also solvable, and the solution shows a zero-temperature quantum phase transition between two non-Fermi liquid chaotic phases. This phase transition is driven by tuning the ratio of two mode numbers, and a nonchaotic Fermi liquid sits at the critical point with an equal number of modes. At a finite temperature, the Fermi liquid phase expands to a finite regime. More intriguingly, a different non-Fermi liquid phase emerges at a finite temperature. We characterize the phase diagram in terms of the spectral function, the Lyapunov exponent, and the entropy. Our results illustrate a concrete example of the quantum phase transition and critical behavior between two non-Fermi liquid phases.

Ülkemizde Yetiştirilen Başlıca Buğday Çeşitlerinin ve Unlarının Tiamin ve Riboflavin Miktarları

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Recai Ercan

2015-02-01

Full Text Available Bu çalışmada, ülkemizde yetiştirilen başlıca buğday çeşitlerinin ve bunların laboratuvar değirmeninde öğütülmesiyle elde edilen unlarının B1 ve B2 vitaminleri miktarı saptanmıştır. Araştırmada 18 buğday çeşidi kullanılmıştır. Buğdaylarda B1 ve B2 vitaminleri miktarı çeşit ve yetişme yerine bağlı olarak değişmektedir. Genellikle sert buğdaylar, yumuşaklardan daha zengin bulunmuştur. Unlarda B1 ve B2 vitamin miktarlarının buğday çeşidi ve randımanı ile ilişkili olduğu görülmüştür. Un randımanı arttıkça vitamin miktarları da artmaktadır.

Yeşilırmak Nehir Teraslarında Toprakların Oluşumu ve Sınıflandırılması

Directory of Open Access Journals (Sweden)

Alper Durak

2014-02-01

Full Text Available Bu çalışmada ana materyali alüviyaller olan, Yeşilırmak nehir terasları üzerinde oluşmuş topraklar incelenmiştir. Bu amaçla çalışma alanında 4 farklı profil açılmıştır. Açılan profillerden horizon esasına göre toplam 27 adet örnek alınmış ve laboratuvarda fiziksel ve kimyasal analizleri yapılmıştır. Tanımlanan profiller Toprak Taksonomisi’ne göre, Alt grup düzeyinde; Kum Ocağı ve Çakıl profilleri Typic Ustipsamments, Havaalanı profili Typic Haplustolls ve Mera profili ise Typic Argiustolls olarak sınıflandırılmıştır. Toprakların pH değerleri 7,38-8,41 arasında değişmekte olup, topraklar hafif ve kuvvetli bazik reaksiyonlu olarak sınıflandırılmıştır. Toprakların çoğunda, pH değerleri profil içinde düzensiz olarak dağılmıştır. Bir kısmında is pH değerlerinde derinliğe bağlı olarak artış görülmüştür. Çalışma alanı topraklarında kireç %0,8-25,4 arasında değişmiştir. Toprakların kireç içerikleri geniş sınırlar içinde değişmesine rağmen, büyük çoğunluğu fazla kireçli olarak sınıflandırılmıştır. Toprakların önemli bir kısmında, kireç profil içinde düzensiz olarak dağılmıştır. Topraklarda organik madde içeriği %0,14-6,11 arasındadır. Toprakların organik madde içerikleri geniş sınırlar içerisinde değişim göstermesine rağmen, büyük çoğunluğunun organik madde içeriği düşük düzeydedir. Organik madde içeriği sadece iki profilin yüzey horizonlarında %4’ün üzerindedir. Çalışma sonunda alüviyal ana materyal, tekstür, topoğrafya ve zamanın; tanımlanan toprakların oluşumunu farklı derecede etkilediği ortaya konmuştur.

Tarım İşletmelerinde Buğday Tohumu Kullanımı ve Sorunları: Burdur ve Isparta İlleri Örneği

Directory of Open Access Journals (Sweden)

Hülya Gül

2015-09-01

Full Text Available Çalışmanın temel hedefi Isparta-Burdur illerinde buğday üretimindeki tohum kullanım yapısının tespiti ve üretimin geliştirilmesidir. Araştırmada kullanılan birincil veriler, bölgede buğday yetiştiriciliği yapan işletmelerden anket yöntemi ile elde edilmiştir. Buğday yetiştiriciliği yapan 150 işletmeden elde edilen veriler 2011 üretim dönemine aittir. Buğday üretiminde işletme genel ortalamasında işletmecilerin karşılaştığı sorunların başında ürün fiyatının düşük olması, girdi fiyatlarının yüksekliği gelmektedir. İşletmecilerin buğday üretiminin geliştirilmesinin, üretimde kullanılan mazot, ilaç, gübre gibi girdi maliyetlerinin düşürülmesi ile sağlanabileceğini ifade etmişlerdir. Buğday tarımında tohum ilaçlaması bölgede işletmelerin %97,3’ünde yapılmaktadır. Buğday tarımında üretim sonrası buğday ürününün depolama durumu ise görüşülen işletmelerin %52,7’sinde söz konusudur. İşletmelerin %74,7’si yetiştirdiği buğday çeşidini bilmektedir. İşletmelerin %52’sinde de sertifikalı tohum kullanımının olduğu saptanmıştır. Sertifikalı tohum kullanım oranı Isparta ilinde daha yüksektir (%69,3. İstatistikî olarak da iller arasında sertifikalı tohum kullanımında farklılık bulunmaktadır. Bölgede işletmelerin sertifikalı tohum kullanımı konusunda yeterli bilgiye sahip olmadığı saptanmıştır. Dolayısıyla bu konuda yayımcılar tarafından üreticiye bilgi aktarımı gerekmektedir.

[Textual research on Chen Ye and his Jia cang jing yan fang (Family-preserved Empirical Recipes) of the Song Dynasty].

Science.gov (United States)

Zhang, Xuedan; Zhang, Ruqing; Chen, Dexing

2014-01-01

Chen Ye, an official of the Southern Song Dynasty, also known as Chen Rihua as his styled name, was born in Changle, Fuzhou in the reign of Shaoxing, and died during the reign of Duanping. He had been consecutively in the positions of Jiang shi lang (Court Gentleman for Ceremonial Service), Zhi zhou (Prefect) of Lingding, the Ti xing (Judicial Commissioner) of Guangdong, the Zong ling (Overseer-general) of Sichuan, Shan ding (Reviser), Shu lin and other positions in Tongzhou, Yuanzhou. His works included 1 volume of Gu ling xian sheng nian pu (Mr. Guling's Chronological Biography), 1 volume of Tan xie (On Humor), 1 volume of Shi hua (Poetry), 8 volumes of Jin yuan li shu (Jin Yuan's Smart Technique), 3 volumes of Yi jian zhi lei bian (Classified Compilation of Yijian's Annals), (Zeng guang) Suo sui lu (Augmented Records of Trivial Matters), 5 volumes of Jia cang jing yan fang (Family-preserved Empirical Recipes). He also compiled the 8-volume Yin jiang zhi (Yinjiang's Annals), published the 2-volume Jia cang ji yao fang (Collected Essential Recipes from Family Preservation), and other proses and poetry. Jia cang jing yan fang was a formulary compiled by Chen Ye, which was lost. Altogether 74 of its recipes were cited in Fu ren da quan liang fang (Complete Effective Prescriptions for Women's Diseases), Shou qin yang lao shu (A Book for Pursuing Seniors' Longevity and Healthcare), Pu ji fang (Prescriptions for Universal Relief) and Yong le da dian (Yongle Encyclopedia).

Behavioral, neuroendocrine and neurochemical effects of the imidazoline I2 receptor selective ligand BU224 in naive rats and rats exposed to the stress of the forced swim test.

Science.gov (United States)

Finn, David P; Martí, Octavi; Harbuz, Michael S; Vallès, Astrid; Belda, Xavier; Márquez, Cristina; Jessop, David S; Lalies, Margaret D; Armario, Antonio; Nutt, David J; Hudson, Alan L

2003-05-01

There is evidence for alterations in imidazoline(2) (I(2)) receptor density in depressed patients. Selective I(2) receptor ligands modulate central monoamine levels and activate the hypothalamo-pituitary-adrenal (HPA) axis and may have potential as antidepressants. To study the behavioral effects of the selective I(2) receptor ligand BU224 in the rat forced swim test (FST) and its effects on the HPA axis and central monoaminergic responses. Rats received saline or BU224 (10 mg/kg IP) 24, 18 and 1 h prior to 15 min exposure to the FST. Saline- and BU224-treated non-stressed groups were included. Time spent immobile, struggling and swimming calmly was measured. Plasma adrenocorticotrophic hormone (ACTH) and corticosterone levels 90 min post-BU224 were measured in addition to tissue levels of monoamines and metabolites in the frontal cortex, hippocampus and hypothalamus. Administration of BU224 significantly reduced immobility and increased mild swimming without affecting struggling. Exposure to the FST significantly increased plasma ACTH and corticosterone levels. BU224 administration also increased ACTH and potentiated the ACTH response to FST with no effect on corticosterone. BU224 administration significantly increased frontal cortex 5-hydroxytryptamine (5-HT) levels and decreased 5-HT turnover in the frontal cortex and hypothalamus of rats exposed to FST. In non-stressed rats, BU224 decreased 5-HT turnover in the hippocampus and hypothalamus and decreased norepinephrine turnover in the frontal cortex. The selective I(2) receptor ligand BU224 reduces immobility of rats in the FST, indicative of antidepressant-like activity. This effect is accompanied by alterations in HPA axis and central monoaminergic activity.

Laryngeal cancer at the Korle Bu Teaching Hospital Accra Ghana

International Nuclear Information System (INIS)

Kitcher, E.D.; Cheyuo, C.; Yarney, J.; Gyasi, R. K.

2006-01-01

Laryngeal cancer is the commonest head and neck cancer seen at the Ear Nose and Throat (ENT) Unit Korle Bu Teaching Hospital. The aim of this study was to determine the number of cases of laryngeal cancer seen at the Korle Bu Teaching Hospital, establish epidemiological parameters of the disease and to outline preventive measures. One hundred and fifteen (115) patients who were managed for laryngeal cancer from 1st January 1998 to 31st December 2003 were studied retrospectively with respect to age, sex, duration of symptoms at presentation, risk factors, symptoms complex, histopathology, stage of tumor, details of treatment offered and follow up. The age range was 17-85 years with a mean of 55.5 years (SD10.7). Majority of the patients (90.4%) were above 40 years. The commonest symptom at presentation was dysphonia. A significant proportion of cases (37.3%) presented with locally advanced disease. The commonest histological type of laryngeal tumour seen was squamous cell carcinoma. The treatment offered consisted of radiotherapy for 83 (79.8%) patients and total laryngectomy with neck dissection when necessary for 17 (16.3%) patients who also had postoperative radiotherapy. Only 58 (69.9%) patients completed radiotherapy treatment and in all 32 (24.3 %) patients did not report for any treatment. Majority of patients failed to report for post treatment follow-up. We conclude that significant number of patients with laryngeal cancer presented with locally advanced disease and dysphonia was the commonest symptom. (au)

The VLBA-BU-BLAZAR Multi-Wavelength Monitoring Program

Directory of Open Access Journals (Sweden)

Svetlana Jorstad

2016-10-01

Full Text Available We describe a multiwavelength program of monitoring of a sample of bright γ-ray blazars, which the Boston University (BU group has being carrying out since June 2007. The program includes monthly monitoring with the Very Long Baseline Array at 43 GHz, optical photometric and polarimetric observations, construction and analysis of UV and X-ray light curves obtained with the Rossi X-ray Timing Explorer (RXTE and Swift satellites, and construction and analysis of γ-ray light curves based on data provided by the Large Area Telescope of the Fermi Gamma-ray Space Telescope. We present general results about the kinematics of parsec-scale radio jets, as well as the connection between γ-ray outbursts and jet events.

İLKÖĞRETİM ÖĞRETMEN ADAYLARININ TEKNOLOJİYE YÖNELİK TUTUMLARININ KÜMELEME ANALİZİ

OpenAIRE

ÇELİK, Halil Coşkun; KAHYAOĞLU, Mustafa

2007-01-01

Günümüzde teknolojiyi kullanmak bir ayrıcalık değil, zorunluluk olmuştur. Teknolojik gelişmeler eğitim kurumlarının yapı ve işlevlerini etkilemektedir. Bu nedenle öğretmenlerin de bilgi toplumu bireyleri yetiştirebilmeleri için derslerini teknoloji ile bütünleştirmeleri beklenmektedir. Bu çalışmada, öğretmen adaylarının teknolojiye yönelik tutumlarının kümelenme eğilimleri belirlenmeye çalışılmıştır. Araştırmaya Dicle Üniversitesi Siirt Eğitim Fakültesi İlköğretim Fen Bilgisi, Matematik ve Sı...

İŞLETMELERİN SOSYAL SORUMLULUK ANLAYIŞININ UZANTISI OLARAK YEŞİL PAZARLAMA BAĞLAMINDA YEŞİL REKLAMLAR - GREEN ADVERTISEMENTS IN THE CONTEXT OF GREEN MARKETING AS AN EXTENSION OF THE SOCIAL RESPONSIBILITY UNDERSTANDING OF COMPANIES

Directory of Open Access Journals (Sweden)

Betül ÖZKAYA

2012-11-01

Full Text Available Özet:Ekolojik dengeyi tehdit etmekte olan çevresel sorunlarher geçen gün hızla artmaktadır. Doğal kaynakların azalması,ozon tabakasının incelmesi, hızlı nüfus artışı, su ve havakirliliği gibi dünyanın yaşam kalitesini tehdit eden küreselsorunlar ve bunlara çözüm arayışları sosyal sorumluluk, yeşilpazarlama ve yeşil reklam gibi kavramların öneminiarttırmıştır. İşletme faaliyetlerinin çevreye duyarlı olmasınınen önemli nedeni, özellikle son yıllarda yaşanan küresel çevresorunlarıdır. Küresel çevre sorunları üzerinde işletmelerinetkisi büyüktür. Bu nedenle işletmelerin çevresel sorunlarakarşı sorumlulukları da büyük olmalıdır. Yaşanan bugelişmeler sonucunda işletmeler, toplumun bir üyesi olarakçevre açısından sorumlu bir şekilde davranmaları gerektiğininbilincine varmaya başlamışlar ve bu anlayışı hem ekonomikhem de sosyal faaliyetleri ile de bütünleştirerek yeşilpazarlama ve yeşil reklam faaliyetlerine yoğun bir şekildeyansıtma çabası içine girmişlerdir.Abstract:Environmental problems that severely threatens theecological balance increases day by day. The global problems;the decline of the natural resources, continuous depletion ofthe ozone layer, rapid population increase, water and airpollutions, that threatens the quality of world's life and thesearch for solution, social responsibility brings and emphasizethe concepts such as green marketing and greenadvertisement. The main reason why the company activitiesare sensitive about environment is expressly the recent globalenvironmental problems. Managements have an unfavorableeffect on global environmental problems, that's why they musthave a heavy responsibility. As a result of the latestdevelopments managements as a member of the society, theycomprehended the fact that they also must act responsibly andthis responsible understanding must be integrated with botheconomical and social activities to

Barış Harekâtı Sonrasında Adana’dan Kıbrıs’a Gerçekleştirilen Nüfus Nakli (1975-1976)

OpenAIRE

ÇANAK, Erdem

2015-01-01

1571-1878 yılları arasında Osmanlı Devleti’nin hâkimiyeti altında bulunan Kıbrıs, 1878 yılında geçici olarak, Lozan Antlaşması ile de resmen İngiltere’ye geçmiştir. Bu durumdan faydalanmak isteyen Rumlar da “Enosis”e yönelik faaliyetlerine hız vermişlerdir. Adadaki Türklerin var olma mücadelesine neden olan bu süreç, 1974 Barış Harekâtı ile neticelenmiştir. Ancak Türkler, Barış Harekâtı’na kadar olan dönemde maruz kaldıkları baskıdan dolayı zaman zaman başta Türkiye olmak üzere dünyanın farkl...

A useful PET probe [11C]BU99008 with ultra-high specific radioactivity for small animal PET imaging of I2-imidazoline receptors in the hypothalamus

International Nuclear Information System (INIS)

Kawamura, Kazunori; Shimoda, Yoko; Yui, Joji; Zhang, Yiding; Yamasaki, Tomoteru; Wakizaka, Hidekatsu; Hatori, Akiko; Xie, Lin; Kumata, Katsushi; Fujinaga, Masayuki; Ogawa, Masanao; Kurihara, Yusuke; Nengaki, Nobuki; Zhang, Ming-Rong

2017-01-01

Introduction: A positron emission tomography (PET) probe with ultra-high specific radioactivity (SA) enables measuring high receptor specific binding in brain regions by avoiding mass effect of the PET probe itself. It has been reported that PET probe with ultra-high SA can detect small change caused by endogenous or exogenous ligand. Recently, Kealey et al. developed [ 11 C]BU99008, a more potent PET probe for I 2 -imidazoline receptors (I 2 Rs) imaging, with a conventional SA (mean 76 GBq/μmol) showed higher specific binding in the brain. Here, to detect small change of specific binding for I 2 Rs caused by endogenous or exogenous ligand in an extremely small region, such as hypothalamus in the brain, we synthesized and evaluated [ 11 C]BU99008 with ultra-high SA as a useful PET probe for small-animal PET imaging of I 2 Rs. Methods: [ 11 C]BU99008 was prepared by [ 11 C]methylation of N-desmethyl precursor with [ 11 C]methyl iodide. Biodistribution, metabolite analysis, and brain PET studies were conducted in rats. Results: [ 11 C]BU99008 with ultra-high SA in the range of 5400–16,600 GBq/μmol were successfully synthesized (n = 7), and had appropriate radioactivity for in vivo study. In the biodistribution study, the mean radioactivity levels in all investigated tissues except for the kidney did not show significant difference between [ 11 C]BU99008 with ultra-high SA and that with conventional SA. In the metabolite analysis, the percentage of unchanged [ 11 C]BU99008 at 30 min after the injection of probes with ultra-high and conventional SA was similar in rat brain and plasma. In the PET study of rats' brain, radioactivity level (AUC 30–60 min ) in the hypothalamus of rats injected with [ 11 C]BU99008 with ultra-high SA (64 [SUV ∙ min]) was significantly higher than that observed for that with conventional SA (50 [SUV ∙ min]). The specific binding of [ 11 C]BU99008 with ultra-high SA (86% of total binding) for I 2 R was higher than that of

Twitter.com kā korporatīvo sabiedrisko attiecību instruments Latvijā: satura analīze

OpenAIRE

Lulle, Katrīna

2010-01-01

Bakalaura darba tēma ir „Twitter.com kā korporatīvo sabiedrisko attiecību instruments Latvijā: satura analīze”. Darba ietvaros analizēti 10 Latvijas uzľēmumu Twitter.com profilu ieraksti laika periodā no 2009. gada decembra līdz 2010. gada februārim, kopumā 2780 ieraksti. Darba mērķis ir veikt Latvijas uzľēmumu Twitter.com profilu satura analīzi, lai noteiktu, kā Twitter.com tiek izmantots kā korporatīvo sabiedrisko attiecību instruments. Darbā ir divas teorētiskās nodaļas par sabied...

Closure plan for Corrective Action Unit 109: U-2bu subsidence crater, Nevada Test Site, Nevada

International Nuclear Information System (INIS)

1999-03-01

The U-2bu subsidence crater, Corrective Action Unit 109, will be closed in accordance with the Resource Conservation and Recovery Act, the Nevada Division of Environmental Protection operational permit, and the Federal Facility Agreement and Consent Order. The U-2bu subsidence crater is located in Area 2 of the Nevada Test Site. It was created in 1971 by an underground nuclear test with the name Miniata. The crater has a diameter of 288 meters (944 feet) and an approximate depth of 35 meters (115 feet). Based on the results of the analyses reported in the site characterization report, the only constituents of concern in the U-2bu subsidence crater include leachable lead and total petroleum hydrocarbons. Closure activities will include the excavation and disposal of impacted soil from the top of the crater. Upon completion of excavation, verification samples will be collected to show that the leachable lead has been removed to concentrations below the regulatory action level. After sample results show that the lead has been removed, the excavated area will be backfilled and a soil flood diversion berm will be constructed as a best management practice. An independent registered professional engineer will certify the site was closed following the approved Closure Plan. Post-closure care is not warranted for this site because closure activities will involve removal of the Resource Conservation and Recovery Act constituents of concern

Closure plan for Corrective Action Unit 109: U-2bu subsidence crater, Nevada Test Site, Nevada

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-03-01

The U-2bu subsidence crater, Corrective Action Unit 109, will be closed in accordance with the Resource Conservation and Recovery Act, the Nevada Division of Environmental Protection operational permit, and the Federal Facility Agreement and Consent Order. The U-2bu subsidence crater is located in Area 2 of the Nevada Test Site. It was created in 1971 by an underground nuclear test with the name Miniata. The crater has a diameter of 288 meters (944 feet) and an approximate depth of 35 meters (115 feet). Based on the results of the analyses reported in the site characterization report, the only constituents of concern in the U-2bu subsidence crater include leachable lead and total petroleum hydrocarbons. Closure activities will include the excavation and disposal of impacted soil from the top of the crater. Upon completion of excavation, verification samples will be collected to show that the leachable lead has been removed to concentrations below the regulatory action level. After sample results show that the lead has been removed, the excavated area will be backfilled and a soil flood diversion berm will be constructed as a best management practice. An independent registered professional engineer will certify the site was closed following the approved Closure Plan. Post-closure care is not warranted for this site because closure activities will involve removal of the Resource Conservation and Recovery Act constituents of concern.

10- 12 gadus vecu bērnu ar atkārtotu nesekmību iemācītās bezpalīdzības saistība ar vecāku iemācīto bezpalīdzību

OpenAIRE

Lamstere, Jolanta

2006-01-01

Darbā tika pētīta iemācītās bezpalīdzības saistība bērniem ar vecāku iemācīto bezpalīdzību. Pētījuma gaitā tika izvirzīti pētījuma jautājumi: vai pastāv statistiski nozīmīgas sakarības starp iemācītās bezpalīdzības rādītājiem 10- 12 gadus veciem bērniem ar atkārtotu nesekmību un viņu vecāku iemācītās bezpalīdzības rādītājiem; vai pastāv statistiski nozīmīgas atšķirības starp iemācītās bezpalīdzības rādītājiem bērniem ar atkārtotu nesekmību un sekmīgiem bērniem; vai pastāv statistiski nozīmīga...

Synthesis and some coordination chemistry of the PSnP pincer-type stannylene Sn(NCH2PtBu2)2C6H4, attempts to prepare the PSiP analogue, and the effect of the E atom on the molecular structures of E(NCH2PtBu2)2C6H4 (E = C, Si, Ge, Sn).

Science.gov (United States)

Brugos, Javier; Cabeza, Javier A; García-Álvarez, Pablo; Pérez-Carreño, Enrique; Polo, Diego

2018-03-26

The non-donor-stabilized PSnP pincer-type stannylene Sn(NCH2PtBu2)2C6H4 (1) has been prepared by treating SnCl2 with Li2(NCH2PtBu2)2C6H4. All attempts to synthesize the analogous PSiP silylene by reduction of the (previously unknown) silanes SiCl2(NCH2PtBu2)2C6H4 (2), SiHCl(NCH2PtBu2)2C6H4 (3) and SiH(HMDS)(NCH2PtBu2)2C6H4 (4; HMDS = N(SiMe3)2) have been unsuccessful. The almost planar (excluding the tert-butyl groups) molecular structure of stannylene 1 (determined by X-ray crystallography) has been rationalized with the help of DFT calculations, which have shown that, in the series of diphosphanetetrylenes E(NCH2PtBu2)2C6H4 (E = C, Si, Ge, Sn), the most stable conformation of the compounds with E = Ge and Sn has both P atoms very close to the EN2C6H4 plane, near (interacting with) the E atom, whereas for the compounds with E = C and Si, both phosphane groups are located at one side of the EN2C6H4 plane and far away from the E atom. The size of the E atom and the strength of stabilizing donor-acceptor PE interactions (both increase on going down in group 14) are key factors in determining the molecular structures of these diphosphanetetrylenes. The syntheses of the chloridostannyl complexes [Rh{κ2Sn,P-SnCl(NCH2PtBu2)2C6H4}(η4-cod)] (5), [RuCl{κ2Sn,P-SnCl(NCH2PtBu2)2C6H4}(η6-cym)] (6) and [IrCl{κ2Sn,P-SnCl(NCH2PtBu2)2C6H4}(η5-C5Me5)] (7) have demonstrated the tendency of stannylene 1 to insert its Sn atom into M-Cl bonds of transition metal complexes and the preference of the resulting PSnP chloridostannyl group to act as a κ2Sn,P-chelating ligand, maintaining an uncoordinated phosphane fragment. X-ray diffraction data (of 6), 31P{1H} NMR data (of 5-7) and DFT calculations (on 6) are consistent with the existence of a weak PSn interaction involving the non-coordinated P atom of complexes 5-7, similar to that found in stannylene 1.

Reactions of the dirhenium(II) complexes Re2X4(dppm)2 (X = Cl, Br; dppm = Ph2PCH2PPh2) with isocyanides. 5. Mixed carbonyl-isocyanide and carbonyl-isocyanide-nitrile complexes of stoichiometry (Re2Cl3(dppm)2(CO)(CNR)(L))PF6 (R = t-Bu, xyl (Xylyl); L = t-BuNC, xylNC, MeCN, EtCN). Structural characterization of the cation (Cl2(CO)Re(μ-dppm)2ReCl (CN-t-Bu)2)+

International Nuclear Information System (INIS)

Fanwick, P.E.; Price, A.C.; Walton, R.A.

1988-01-01

Several dirhenium (II) species that contain mixed sets of carbonyl, isocyanide, and/or nitrile ligands have been prepared from the reactions between Re 2 Cl 4 (dppm) 2 (CO)(CNR) (dppm = Ph 2 PCHPPh 2 ; R = t-Bu, xyl (xylyl)), and the appropriate ligands in the presence of TlPF 6 . The crystal structures of these compounds are reported. The terminally-bound ligand noted in the complexes (Re 2 Cl 3 (dppm) 2 (CO)(CN-t-Bu) 2 )PF 6 and (Re 2 CL 3 (dppm) 2 (CO)(CN-t-Bu)(CNxyl))PF 6 indicates structures that have not been previously reported. Complexes in which there are mixed sets of carbonyl, isocyanide, and nitrile ligands, viz. (Re 2 Cl 3 (dppm) 2 (CO)(CNR)(CNR'))PF 6 are also reported. 20 refs., 1 fig., 5 tabs

Research on Spontaneously Emerged Chromosomal Aberrations in the Periphery Blood Lymphocytes in Cattle (‘Buša’ Breed

Directory of Open Access Journals (Sweden)

Danica Hasanbašić

2007-11-01

Full Text Available Knowledge of spontaneous aberrations, namely, of their frequency in non-irradiated cells is of paramount importance not only in cytogenetic research, but also in contemporary animal production.The paper deals with research on spontaneously emerged chromosomal aberrations in the peripheral blood lymphocytes in the cattle of ‘Buša’ breed.To obtain metaphase chromosomes the conventional method of lymphocyte cultivation was used, albeit slightly modified and adapted to the examined animals and the laboratory conditions.The research findings indicate that a certain percent of spontaneously emerged chromosomal aberrations of chromatid type (gap and break have been found in the peripheral blood lymphocytes in the cattle of ‘Buša’ breed.

Latvijas sabiedrisko attiecību līderu novērtējums: mediju, SA aģentūru, klientu un topošo SA speciālistu viedokļi

OpenAIRE

Freiberga, Anna

2017-01-01

Bakalaura darba ‘’Latvijas sabiedrisko attiecību līderu novērtējums: mediju, SA aģentūru, klientu un topošo SA speciālistu viedokļi’’ pētījuma problēma ir Latvijas sabiedrisko attiecību nozarē nav noteikti konkrēti līderi. Bakalaura darbs sastāv no teorētiskās, metodoloģiskās un empīriskās daļas. Teorētiskajā daļā ir aprakstīta Sabiedrisko attiecību teorija, sabiedrisko attiecību raksturojums un vēsture, sabiedrisko attiecību mērķi, iezīmju teoriju, uzvedības iezīmju teoriju, līdera teoriju,...

LGBT tiesību pārstāvniecība Eiropas Savienībā

OpenAIRE

Mūsiņa, Santa

2014-01-01

Bakalaura darbā „LGBT tiesību pārstāvniecība Eiropas Savienībā” galvenā uzmanība pievērsta LGBT interešu pārstāvībai ES, analizējot interešu grupu spēju īstenot LGBT lobija aktivitātes ES institucionālajā ietvarā. Pētījumā mēģināts noskaidrot, kāpēc LGBT organizācijām līdz šim nav izdevies panākt ES LGBT likumdošanas paplašināšanu, pievēršot uzmanību organizāciju lobija stratēģijām. Darba teorētiskā pieeja balstās uz lobija efektivitātes principiem, kurus adap...

Sacensību trauksmes saistība ar sportisko sniegumu treniņos un sacensībās skeletonā un kamaniņu sportā

OpenAIRE

Lemberga, Krista

2017-01-01

Pētījuma mērķis bija izpētīt trauksmes pirms sacensībām saistību ar sniegumu tajās salīdzinājumā ar trauksmi pirms treniņiem un sniegumu tajos, noskaidrot, kāda ir sportistu trauksmes saistība ar sacensību pieredzi, kā arī izpētīt iespējamās atšķirības gan sportistu trauksmē pirms treniņiem un sacensībām, gan sportiskajā sniegumā treniņos un sacensībās. Sacensību trauksme tika mērīta retrospektīvi ar Pārskatītās Sacensību trauksmes kā stāvokļa aptauju – 2 (Revised Competitive State Anxiety In...

Potential therapeutic agents for circulatory diseases from Bauhinia glauca Benth.subsp. pernervosa. (Da Ye Guan Men).

Science.gov (United States)

Tang, Yingzhan; Ling, Junhong; Zhang, Peng; Zhang, Xiangrong; Zhang, Na; Wang, Wenli; Li, Jiayuan; Li, Ning

2015-08-15

Because of platelets as critical factor in the formation of pathogenic thrombi, anti-platelet activities have been selected as therapeutic target for various circulatory diseases. In order to find potential therapeutic agents, bioassay-directed separation of Bauhinia glauca Benth.subsp. pernervosa. (called Da Ye Guan Men as a traditional Chinese medicine) was performed to get 29 main components (compounds 1-29) from the bioactive part of this herbal. It was the first time to focus on the composition with anti-platelet aggregation activities for this traditional Chinese medicine. The constituents, characterized from the effective extract, were established on the basis of extensive spectral data analysis. Then their anti-platelet aggregation effects were evaluated systematically. On the basis of the chemical profile and biological assay, it was suggested that the flavonoid composition (5 and 18) should be responsible for the anti-platelet aggregation of the herbal because of their significant activities. The primary structure and activity relationship was also discussed briefly. Copyright © 2015. Published by Elsevier Ltd.

Effect of newly synthesized compounds 44Bu and 444 on QRS -complex width and fast sodium current

Czech Academy of Sciences Publication Activity Database

Kilianová, A.; Bébarová, M.; Beránková, K.; Opatřilová, R.; Pásek, Michal; Bartošová, L.

2010-01-01

Roč. 79, č. 1 (2010), s. 41-49 ISSN 0001-7213 Institutional research plan: CEZ:AV0Z20760514 Keywords : 444 * 44Bu * QRS-complex * sodium current * rat Subject RIV: BO - Biophysics Impact factor: 0.534, year: 2010

Attiecība starp varu un cilvēcību F. Kafkas „Metamorfoze”: interpretēta japāņu manga

OpenAIRE

Geplere, Jeļena

2016-01-01

Bakalaura darba tēma ir Franca Kafkas romānā „Metamorfoze” atrodamu varas attiecību interpretācija un analīze japāņu manga medijos, balstoties uz Bjorna Krausa un Edvarda Šila varas teorijām. Darbā tika izstrādāts salīdzinošais multimediju pētījums, kura mērķis ir pierādīt un aprakstīt attiecību starp cilvēcību un varu Kafkas darbā, kā arī identificēt kā šī attiecība tiek parādīta „Metamorfozes” ietekmētajās darbos.Pētījuma rezultāti rāda, ka „Metamorfozē” un analizētājās manga eksistē iekšēj...

KALKINMA GELİR EŞİTSİZLİĞİ İLİŞKİSİ: TÜRKİYE ÖRNEĞİ

OpenAIRE

ÖZTÜRK, Eray; OKTAR, Suat

2018-01-01

Ülkeler kalkındıkça yaratılan refahınnasıl paylaşılacağı da iktisadi bir sorun olarak gündeme gelmektedir. Bu makaleTürkiye için 1990 sonrası dönemde kalkınma ve gelir eşitsizliği ilişkisiniincelemektedir. Bugüne kadar yapılan çalışmalar kişi başına gelir ile gelireşitsizliğini ilişkilendirirken,bu makalede kişi başına gelir yerine Birleşmiş milletlerin kalkınma ölçütü olanİnsani Gelişmişlik Endeksi (HDI) kullanılmıştır. İnsani Gelişme Endeksibireylerin refahını ölçtüğü için kişi başına gelir...

Uşak İli Buğday Ekim Alanlarında Süne, [Eurygaster spp. (Hemiptera: Scutelleridae] Yumurtalarının Parazitlenme Oranları ile Buğday Tanelerindeki Emgi Oranları Arasındaki İlişkinin Belirlenmesi

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Erdal ZENGİN

2017-06-01

Full Text Available Bu çalışma, 2015-2016 yıllarında Uşak iline bağlı 10 köydeki Süne yumurtalarının parazitlenme oranlarının ve emgili tane sayılarının belirlenmesi ile bu oranlar arasındaki ilişkinin tespit edilmesi amacıyla yapılmıştır. Araştırma sonuçlarına göre, 2015 ve 2016 yıllarındaki en yüksek Süne yumurtası parazitlenme oranı ve emgili tane sayıları sırasıyla %95.4-%1.60, %90.7-%1.05 olarak bulunmuştur. Köylerde yapılan arazi çalışmaları sonucunda elde edilen oranlara çoklu karşılaştırma testi uygulanarak köyler arasındaki farklılıklar belirlenmiştir.  Parazitlenme oranı ile emgili tane sayısı arasında bir ilişkinin olup olmadığını belirlemek için her iki yıl verileri üzerinde yapılan regresyon analizi sonucunda, bu iki değişken arasında doğrusal bir ilişkinin olduğu tespit edilmiştir.

Kinetics and Mechanism of the Polymerization of Methyl Methacrylate in a Y(acac)3/n-BuMgCl System

Institute of Scientific and Technical Information of China (English)

无

2000-01-01

Based on the kinetics equation proposed by T. Kagiya, the kinetic study on the polymerization of methyl methacrylate(MMA) by Y(acac)3/n-BuMgCl was carried out with a dilatometer. It was found that the rate of propagation is the first order with respect to the concentration of both active center and monomer. Thus, the equation of propagation rate can be described as Rp=Kp[c*][M]. In addition, the instantaneous chain initiation and single molecular termination were concluded for the present system. The activation energy is close to 32 kJ/mol. In the polymerization, n-BuMgCl acts not only as the cocatalyst, but also as chain transfer agent with cI=3.6×10-4.

Intramolecular electron transfer in cyanide bridged adducts comprising Ru(II)/Ru(III) tetracarboxylate and [Mn(I)(CO)(CN)((t)BuNC)(4)] units.

Science.gov (United States)

Imhof, Wolfgang; Sterzik, Anke; Krieck, Sven; Schwierz, Markus; Hoffeld, Thomas; Spielberg, Eike T; Plass, Winfried; Patmore, Nathan

2010-07-21

Reaction of mixed valence ruthenium tetracarboxylates [Ru(2)(II,III)(R(1)COO)(2)(R(2)COO)(2)Cl] (R(1) = Me, R(2) = 2,4,6-(i)Pr-Ph or R(1) = R(2) = (t)Bu) with two equivalents of the octahedral manganese complex [Mn(I)(CO)(CN)((t)BuNC)(4)] leads to the formation of cyanide bridged heteronuclear coordination compounds of the general formula {[Ru(2)(II,III)(R(1)COO)(2)(R(2)COO)(2)][Mn(I)(CO)(CN)((t)BuNC)(4)](2)}Cl. In solution an intramolecular electron transfer from manganese towards the multiply bonded Ru(2) core occurs that is verified by EPR and IR spectroscopy, magnetic measurements and DFT calculations. Nevertheless, disproportionation of an initially formed {Mn(I)-Ru(2)(II,III)-Mn(I)}(+) adduct into {Mn(II)-Ru(2)(II,III)-Mn(I)}(2+) and {Mn(I)-Ru(2)(II,II)-Mn(I)} species cannot be completely ruled out.

Transformation of Au144(SCH2CH2Ph)60 to Au133(SPh-tBu)52 Nanomolecules: Theoretical and Experimental Study.

Science.gov (United States)

Nimmala, Praneeth Reddy; Theivendran, Shevanuja; Barcaro, Giovanni; Sementa, Luca; Kumara, Chanaka; Jupally, Vijay Reddy; Apra, Edoardo; Stener, Mauro; Fortunelli, Alessandro; Dass, Amala

2015-06-04

Ultrastable gold nanomolecule Au144(SCH2CH2Ph)60 upon etching with excess tert-butylbenzenethiol undergoes a core-size conversion and compositional change to form an entirely new core of Au133(SPh-tBu)52. This conversion was studied using high-resolution electrospray mass spectrometry which shows that the core size conversion is initiated after 22 ligand exchanges, suggesting a relatively high stability of the Au144(SCH2CH2Ph)38(SPh-tBu)22 intermediate. The Au144 → Au133 core size conversion is surprisingly different from the Au144 → Au99 core conversion reported in the case of thiophenol, -SPh. Theoretical analysis and ab initio molecular dynamics simulations show that rigid p-tBu groups play a crucial role by reducing the cluster structural freedom, and protecting the cluster from adsorption of exogenous and reactive species, thus rationalizing the kinetic factors that stabilize the Au133 core size. This 144-atom to 133-atom nanomolecule's compositional change is reflected in optical spectroscopy and electrochemistry.

tBuLi-Mediated One-Pot Direct Highly Selective Cross-Coupling of Two Distinct Aryl Bromides

NARCIS (Netherlands)

Vila, Carlos; Cembellin, Sara; Hornillos, Valentin; Giannerini, Massimo; Fananas-Mastral, Martin; Feringa, Ben L.

2015-01-01

A Pd-catalyzed direct cross-coupling of two distinct aryl bromides mediated by tBuLi is described. The use of [Pd-PEPPSI-IPr] or [Pd-PEPPSI-IPent] as catalyst allows for the efficient one-pot synthesis of unsymmetrical biaryls at room temperature. The key for this selective cross-coupling is the use

Türkiye’ye Gelen Yabancı Turistlerin Gelir Düzeyi Kümelerinin Yıllara Göre Değişimi

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Nurzen ÜZÜMCÜ

2016-03-01

Full Text Available Bu çalışmada yabancı turistlerin milliyetlerinin gelir düzeyine göre 2007-2012 arasındaki her yıl için kümelemesi yapılmıştır. Burada amaç, “Yüksek”, “Orta” “Düşük” olarak etiketlenen gelir düzeyi kümelerinde yer alan ülkelerin yıllar içerisindeki değişimini gözlemlemektir. Bu çalışmanın, yıllar itibariyle gelir düzey grupları değişkenlik gösteren turistlerin geldiği ülkelerin tespit edilmesi, bu değişikliğinin sebeplerinin araştırılması ve gelir düzeyi grupları için ortak turizm stratejileri geliştirilmesi açısından yol gösterici olması amaçlanmaktadır. Veri seti TUIK’in web sitesinden elde edilmiştir. Kümeleme için Bulanık C-Ortalamalar kullanılmıştır. Yapılan analizler neticesinde, aynı ülkelerden gelen yabancı turistlerin gelir düzeylerinin yıllar itibari ile çok değişkenlik göstermediği, ancak genellikle “düşük” gelir gruplu turistlerin geldiği gözlenmiştir.

THE ANALYSIS OF LETÂİF-NÂME IN TERMS OF THE NOVEL TECHNIQUE ABSTRACT LETÂİF-NÂME ADLI ESERİN ROMAN TEKNİĞİ AÇISINDAN İNCELENMESİ

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Şener DEMİREL

2011-09-01

Full Text Available Latife/letâif, meaning pleasant and nice statement humouring and cheering people, especially joking and humor, is conceptually an elusive and delicate meaning, a feeling coming to heart, or an amusing and weird statement and story. And letâif-nâme, derived from the word latife, can be composed of many different texts within itself (e.g. story, tale, joke and epigram, and can be written as a long-running story consisting of a separate text and a certain plot.The story Letâif-nâme, which is the subject of this paper and the author of which is not known, is an example of the latter kind of texts, and stands out as a work including eleven distinct stories / tales / jokes within a framework. This work was published in H.1268/ A.D.1851-52 in İstanbul. The work, comprising 153 pages, tells about the experiences of a hero called Yousuf Shah in the 17th century during the reign of Sultan Murad the fourth. This paper, focusing on the work Letâif-nâme, deals with the title, theme, summary, plot, characters, setting, time, narrator and the point of view of the work, and its linguistic and style characteristics within the framework of the story / novel analysis. İnsanları güldüren, neşelendiren hoş söz ve güzel söz; özellikle şaka, espri anlamına gelen latife/letâif, kavram olarak sözle ifade edilmesi güç, ince mana, kalbe doğan duygu; güldürecek tuhaf söz ve hikâye demektir. Latife kelimesinden türetilen letâif-nâme ise kendi içinde birçok ayrı metinden (hikâye, masal, fıkra ve nükte gibi oluşabildiği gibi, müstakil bir metin, belli bir olay örgüsünden oluşan uzun soluklu hikâye hâlinde de kaleme alınmış olabilmektedir. Bu yazıya konu olan ve yazarı bilinmeyen Letâif-nâme adlı hikâye, ikinci tip metinlere örnektir ve bir çerçeve içinde birbirinden farklı on bir hikâye/masal/fıkrayı içeren bir eser olarak karşımıza çıkmaktadır. Eser, H.1268/M.1851-52 yılında İstanbul’da bas

CNS bioavailability and radiation protection of normal hippocampal neurogenesis by a lipophilic Mn porphyrin-based superoxide dismutase mimic, MnTnBuOE-2-PyP5+

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David Leu

2017-08-01

Full Text Available Although radiation therapy can be effective against cancer, potential damage to normal tissues limits the amount that can be safely administered. In central nervous system (CNS, radiation damage to normal tissues is presented, in part, as suppressed hippocampal neurogenesis and impaired cognitive functions. Mn porphyrin (MnP-based redox active drugs have demonstrated differential effects on cancer and normal tissues in experimental animals that lead to protection of normal tissues and radio- and chemo-sensitization of cancers. To test the efficacy of MnPs in CNS radioprotection, we first examined the tissue levels of three different MnPs – MnTE-2-PyP5+(MnE, MnTnHex-2-PyP5+(MnHex, and MnTnBuOE-2-PyP5+(MnBuOE. Nanomolar concentrations of MnHex and MnBuOE were detected in various brain regions after daily subcutaneous administration, and MnBuOE was well tolerated at a daily dose of 3 mg/kg. Administration of MnBuOE for one week before cranial irradiation and continued for one week afterwards supported production and long-term survival of newborn neurons in the hippocampal dentate gyrus. MnP-driven S-glutathionylation in cortex and hippocampus showed differential responses to MnP administration and radiation in these two brain regions. A better understanding of how preserved hippocampal neurogenesis correlates with cognitive functions following cranial irradiation will be helpful in designing better MnP-based radioprotection strategies. Keywords: Mn porphyrin, Bioavailability, BMX-001, Hippocampus, Neurogenesis, Radioprotection

Süne (Eurygaster spp Hasarlı Buğdayların Bazı Protein Fraksiyonları ve Farinogram Değerleri Üzerine Buharla Tavlamanın Etkileri

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Harun Dıraman

2015-02-01

Full Text Available Süne olarak isimlendirilen böcek hasat öncesinde buğday tanesine etki ederek unun ekmek yapım niteliklerine zarar veren proteolitik enzimleri salgılamaktadır. Süne hasarına uğramış buğdaylardan yapılan hamur, aşırı proteolitik aktivite nedeniyle yapışkan ve cıvık olup, yoğurma güçlüğü göstermektedir. Böcek enziminin proteolitik aktivitesi, buğdayın hasar derecesine bağlı olarak, 70 oC civarındaki sıcaklıkta 1-5 dakikalık buharla tavlama ile inhibe edilebilir. Bu çalışma, kontrol (% 0 süne hasarı, % 4 (±1 süne emgili ve % 9 (±3 süne emgili olmak üzere üç farklı gruptaki ticari buğday paçalında gerçekleştirilmiştir. Bütün örnekler Chopin CD - 1 laboratuvar değirmeninde 20 oC'de % 15.5 nemde öğütülmüştür. Süne hasarlı örnekler 70 oC civarındaki sıcaklıktaki buhara, hasar derecelerine göre 2, 3 ve 6 dakika maruz bırakılmıştır. Buharla tavlama esnasında örneklerin sıcaklığı 62-66 oC arasında değişmiş olup, tavlama işlemi kesikli olarak uygulanmıştır. Bu çalışmada buharla tavlanan süne hasarlı buğdaylarda bazı parametrelerin (toplam protein, %70 alkolde çözünen [gliadin] ve 0.05 M asetik asitte çözünmeyen [glutenin] kalıntı protein fraksiyonları ve farinograf değerlerinin değişimi incelenmiştir. Buharla tavlama ile alkolde çözünür protein (gliadin miktarı azalırken, kalıntı proteinleri (çoğunlukla glutenin miktarı artmıştır. Buharla tavlama sonrasında, farinograf stabilite ve gelişme süresi artmış, yoğurma tolerans indeksi ise azalmıştır. Bu sonuçlar, süne hasarlı buğdayda buharla tavlama nedeniyle, asetik asitte çözünmeyen protein fraksiyonundaki değişimlerle bağlantılı olarak hamur reolojik niteliklerinin iyileştiğini göstermiştir.

Optimization of health-care organization and perceived improvement of patient comfort by switching from intra-venous BU four-times-daily infusions to a once-daily administration scheme in adult hematopoietic stem cell recipients.

Science.gov (United States)

Xhaard, A; Rzepecki, P; Valcarcel, D; Santarone, S; Fürst, S; Serrano, D; De Angelis, G; Krüger, W; Scheid, C

2014-04-01

Previous studies have shown an equivalent pharmacokinetic profile between four-times-daily (4QD) and once-daily (QD) administration of intra-venous (IV) BU, without increased toxicity. We assess the impact of a switch in IV BU from a 4QD to a QD schedule, in terms of health-care organization, staff working conditions, quality of care dispensed and perceived patient comfort. Clinicians, nurses and pharmacists from nine allogeneic transplantation units in five European countries were interviewed face to face. Overall perception of QD versus 4QD BU was very positive. Both administration schemes were evaluated to be equally efficaciousZ. QD BU was perceived to be safer and more convenient. Clinicians and nurses perceived that patient comfort was improved, due to fewer complications associated with repeated infusions, and avoiding night infusions associated with stress, anxiety and decreased quality of sleep. Switching from 4QD to QD BU had a significant impact on health-care organization, with a better integration in the overall management and usual timelines in the pharmacies and transplantation units. Time spent to prepare and administer BU was significantly reduced, leading to potential financial savings that merit further assessment and would be of particular interest in the current economic climate.

İzmir İlinde Bulunan Termal Sularda Gelişen Bazı Termofilik Mavi-Yeşil Alglerin (Siyanobakterilerin İzolasyonu ve Moleküler Tayini.

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Kerem Yüksel

2015-12-01

Full Text Available İzmir ili ve çevresindeki termal tesislerden elde edilen mavi-yeşil algler (siyanobakteriler laboratuar ortamında izole edilip, moleküler yöntemlerle tür tayini çalışılmıştır. Zeytindalı kaplıcaları, Şifne Termal Otel ve Balçova Termal Otel olmak üzere 3 istasyondan elde edilen 4 mavi-yeşil alg (siyanobakteri türü, laboratuarda kültür ortamında saflaştırılarak izole edilmişlerdir. Daha sonra elde edilen hücrelerden, DNA izolasyonu sonucu elde edilen DNA’lar PCR’da çoğaltılmıştır. Siyanobakterilere özgü primerler kullanılarak 16S rRNA gen bölgeleri tekrar PCR’da çoğaltılarak elde edilen dizi analizi verileri bilgisayar programlarında yorumlanarak filogenetik bakımdan tür tayini yapılmaya çalışılmıştır. Dizi analizlerine göre yapılan tür tayini doğrultusunda, örneklerden üçünün Geitlerinema cinsi olduğu diğer 1 türün ise kültürü belirlenmemiş tür olduğu belirtilmiştir

Sabiedrisko attiecību loma uzņēmuma mērķu sasniegšanā: Latvijas Investīciju un attīstības aģentūras gadījuma analīze

OpenAIRE

Adamane, Alise

2014-01-01

Bakalaura darba tēma ir „Sabiedrisko attiecību loma uzņēmuma mērķu sasniegšanā: LIAA gadījuma analīze”. Bakalaura darba mērķis ir noskaidrot, kāda ir sabiedrisko attiecību loma Latvijas Investīciju un attīstības aģentūras mērķu sasniegšanā. Darba teorētiskā bāze sastāv no nodaļas par sabiedrisko attiecību raksturojumu, kas sevī ietver sabiedrisko attiecību skaidrojumu, mērķus, funkcijas, sabiedrisko attiecību modeļus, iekšējo un ārējo komunikāciju un nodaļas par sabiedrisko attiecību sk...

Universality and Thouless energy in the supersymmetric Sachdev-Ye-Kitaev model

Science.gov (United States)

García-García, Antonio M.; Jia, Yiyang; Verbaarschot, Jacobus J. M.

2018-05-01

We investigate the supersymmetric Sachdev-Ye-Kitaev (SYK) model, N Majorana fermions with infinite range interactions in 0 +1 dimensions. We have found that, close to the ground state E ≈0 , discrete symmetries alter qualitatively the spectral properties with respect to the non-supersymmetric SYK model. The average spectral density at finite N , which we compute analytically and numerically, grows exponentially with N for E ≈0 . However the chiral condensate, which is normalized with respect the total number of eigenvalues, vanishes in the thermodynamic limit. Slightly above E ≈0 , the spectral density grows exponentially with the energy. Deep in the quantum regime, corresponding to the first O (N ) eigenvalues, the average spectral density is universal and well described by random matrix ensembles with chiral and superconducting discrete symmetries. The dynamics for E ≈0 is investigated by level fluctuations. Also in this case we find excellent agreement with the prediction of chiral and superconducting random matrix ensembles for eigenvalue separations smaller than the Thouless energy, which seems to scale linearly with N . Deviations beyond the Thouless energy, which describes how ergodicity is approached, are universally characterized by a quadratic growth of the number variance. In the time domain, we have found analytically that the spectral form factor g (t ), obtained from the connected two-level correlation function of the unfolded spectrum, decays as 1 /t2 for times shorter but comparable to the Thouless time with g (0 ) related to the coefficient of the quadratic growth of the number variance. Our results provide further support that quantum black holes are ergodic and therefore can be classified by random matrix theory.

Eitanāzijas kriminalizācija kā cilvēktiesību aizskārums Eiropā

OpenAIRE

Krone, Monta

2015-01-01

Bakalaura darbs „Eitanāzijas kriminalizācija kā cilvēktiesību aizskārums Eiropā” ir uzrakstīts 2015. gadā Latvijas Universitātes Juridiskās fakultātes Starptautisko un Eiropas tiesību zinātņu katedrā. Darbs sastāv no piecām nodaļām. Pirmajā nodaļā ir aprakstīts, kas ir eitanāzija (jēdziena izpratne) un kādas ir tās pazīmes. Tiek apskatīti eitanāzijas veidi, sīkāk raksturojot voluntāro, nevoluntāro un involuntāro eitanāziju, kā arī eitanāzijas vēsturiskā attīstība no 19. gadsimta līdz pat mūsd...

Reactivity of the geminal phosphinoborane tBu2PCH2BPh2 towards alkynes, nitriles, and nitrilium triflates

NARCIS (Netherlands)

Habraken, E.R.M.; Mens, L.C.; Nieger, M.; Lutz, M.; Ehlers, A.W.; Slootweg, J.C.

2017-01-01

The reactivity of the geminal phosphinoborane tBu2PCH2BPh2 towards terminal alkynes, nitriles and nitrilium salts is investigated. Terminal alkynes react via C–H bond splitting (deprotonation) resulting in the formation of phosphonium borates. In contrast, both nitriles and nitrilium salts undergo

EXAMINATION OF GULTEN DAYIOGLU’S CHILDREN STORIES ACCORDING TO THE

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Bekir GÖKÇE*

2011-09-01

Full Text Available The story is one of the literary products, making the taste of reading at the children. However, it is important that the relationship constituted by reading influence the life of the child. This case get attention of researchers and studies on the stories and become the subject of several scientific research. In this study, it considered 67 stories found in Gulten Dayıoglu’s 12 story books who is one of the leading writers of children literature. And it analyzed, by the method of “story map” used for the apprehension of text, 12 stories that are named of 12 story book of Dayıoglu. It concluded then that the method of the story map account plays an important role in the development of four basic language skills (listening, speaking, reading, writing. Öykü, çocuğa okumayı sevdiren edebî metinlerden biridir. Okuma yoluyla kurulan bu ilişki, çocuğu yaşam boyu etkiler. Bu durum, araştırmacıların dikkatini çekmiş; öykü üzerine yapılan incelemeler birçok bilimsel araştırmanın konusu olmuştur. Bu çalışmada; çocuk edebiyatının önde gelen yazarlarından Gülten Dayıoğlu’nun çocuklar için yazdığı 12 öykü kitabında bulunan 67 öykü değerlendirilmiştir. Ancak çalışmanın kapsamı içinde her öykü kitabına ad olan toplam 12 öykü, metin öğretiminde kullanılan “hikâye haritası” yöntemine göre çözümlenmiştir. Öykülerin çözümlenmesinde kullanılan hikâye haritası yönteminin dört temel dil becerisinin (dinleme, konuşma, okuma, yazma gelişiminde önemli bir rol oynadığı sonucuna ulaşılmıştır.

Rasu naida un neiecietību kurināšanas lietas vērtēšanas aspekti

OpenAIRE

Eihmane, Elīna

2010-01-01

Tēma par naidu un neiecietību kurinošo runu jau vairākus gadus ir aktuāla ne tikai Latvijā, bet arī visā pasaulē. Iespējams, tas ir tādēļ, ka pieaug migrācija un līdz ar to valstīs iebrauc aizvien vairāk imigrantu no mazāk attīstītām valstīm, radot arī zināmu sociālo spriedzi uzņemošajā valstī. Otrkārt, fanātiskās kustības ir pastāvējušas gandrīz visos laikos un mūsdienas nav izņēmums un lielā daļā valstu atradīsies grupējumi, kas atbalstīs kādu rasu pārākuma ideju vai reliģisko izredzētību. ...

Re-evaluation of 60Co treatment facility of Korle-Bu Teaching Hospital

International Nuclear Information System (INIS)

Adu, S.

2008-06-01

The radiological protection assessment based on the shielding of the Co-60 Radiotherapy facility at the Korle Bu Teaching Hospital after the source replacement has been carried out. The results indicate that the concrete biological shield is adequate to attenuate the gamma photons from the new 222 TBq Co-60 source in use. The dose rates at critical locations of the public access area are within the recommended dose rate limit of O.5J..1Sv/h and 7.5J..1Sv/h for public and staff respectively. Thus the shielding has not deteriorated and still provides adequate protection for members of the public and the operating staff (au).

Konflikt i wojna jako „bicz Boży” w literaturze bułgarskiego średniowiecza

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Marzanna Kuczyńska

2017-10-01

Full Text Available Conflict and war as the “whip of God” in the literature of the Bulgarian Middle Ages The article focuses on the motif of war as a tool for the realization of God’s plans for people and the sign of His reward, and above all the penalty for human misdeeds, so called “whip of God”. The forms of the presence of the idea of God’s whip, his literary images and the functions it implements, are analyzed. The analysis was carried out on the material of the Bulgarian literature from 10th-15th century.   Konflikt i wojna jako „bicz Boży” w literaturze bułgarskiego średniowiecza Przedmiotem zainteresowania w artykule jest motyw wojny jako narzędzia realizacji Bożych planów wobec ludzi i znaku Jego nagrody, a przede wszystkim kary za ludzkie przewinienia, tzw. „bicz Boży”. Analizowane są formy obecności idei „bicza Bożego”, jego literackie wyobrażenia i funkcje, jakie realizuje. Analizę przeprowadzono na materiale bułgarskiego piśmiennictwa X–XV wieku.

Closure Plan for Corrective Action Unit 109: U-2bu Subsidence Crater Nevada Test Site, Nevada

Energy Technology Data Exchange (ETDEWEB)

Shannon Parsons

1999-03-01

The U-2bu subsidence crater, Corrective Action Unit 109, will be closed in accordance with the Resource Conservation and Recovery Act, the Nevada Division of Environmental Protection operational permit, and the Federal Facilities Agreement and Consent Order. The U-2bu subsidence crater is located in Area 2 of the Nevada Test Site. It was created in 1971 by an underground nuclear test with the name Miniata. The crater has a diameter of 288 meters (944 feet) and an approximate depth of 35 meters (115 feet). The subsidence crater was used as a land disposal unit for radioactive and hazardous waste from 1973 to 1988. Site disposal history is supported by memorandums, letters, and personnel who worked at the Nevada Test Site at the time of active disposal. Closure activities will include the excavation and disposal of impacted soil form the tip of the crater. Upon completion of excavation, verification samples will be collected to show that lead has been removed to concentrations be low regulatory action level. The area will then be backfilled and a soil flood diversion berm will be constructed, and certified by an independent professional engineer as to having followed the approved Closure Plan.

Çeşitli Ekmeklerin Protein, Yağ, Nem, Kül, Karbonhidrat ve Enerji Değerleri

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Nilgün Karaağaoğlu

2015-02-01

Full Text Available Araştırma, Ankara il merkezinden elde edilen 33 ekmek üzerinde gerçekleştirilmiştir. Ekmeklerden alınan ikili veya üçlü örneklerde kül, nem, yağ ve azot (N tayini yapılmıştır. Analiz sonucunda elde edilen N miktarları, tahıl çeşitleri için önerilen katsayılar ile çarpılarak protein miktarları belirlenmiştir. Karbonhidrat ve enerji değerleri ise hesaplanarak bulunmuştur. Beyaz (BE, tam buğday ve köy (TE, kepekli (KE, yulaf (YE ve çavdar (ÇE olmak üzere 5 grupta toplanan ekmek çeşitlerinin protein miktarları arasındaki fark önemli bulunmamıştır (p>0.05. KE grubundaki ekmeklerin yağ miktarı en düşük düzeydedir ve YE ile TE grubundaki ekmeklerle arasındaki fark önemlidir (p<0.05. TE ve KE grubundaki ekmeklerdeki kül miktarı, BE grubundakilerden daha yüksektir (p<0.05. Sonuçlar, beyaz ekmeklerin yapımında kullanılan unlarda, öğütme sırasında kayıpların oluştuğunu göstermektedir. Tam buğday, kepekli, yulaf ve çavdar ekmekleri, içerdikleri diyet posası türleri ve miktarları da düşünüldüğünde, sağlık üzerindeki olumlu etkileri nedeniyle beyaz ekmeğe göre daha iyi seçeneklerdir.

Broadband 2D Electronic Spectroscopy Reveals Coupling Between Dark 1Bu- State of Carotenoid and Qx State of Bacteriochlorophyll

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Scholes Gregory D.

2013-03-01

Full Text Available The study of LH2 protein of purple bacteria by broadband 2D electronic spectroscopy is presented. The dark 1Bu- carotenoid state is directly observed in 2D spectra and its role in carotenoid-bacteriochlorophyll interaction is discussed.

Serum magnesium and calcium in preeclampsia: a comparative study at the Korle-Bu Teaching Hospital, Ghana

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Owusu Darkwa E

2017-08-01

Full Text Available Ebenezer Owusu Darkwa,1 Charles Antwi-Boasiako,2 Robert Djagbletey,1 Christian Owoo,1 Samuel Obed,3,† Daniel Sottie4 1Department of Anaesthesia, University of Ghana School of Medicine and Dentistry, 2Department of Physiology, University of Ghana School of Biomedical and Allied Health Sciences, 3Department of Obstetrics and Gynaecology, University of Ghana School of Medicine and Dentistry, College of Health Sciences, 4Department of Anaesthesia, Korle-Bu Teaching Hospital, Accra, Ghana †Samuel Obed passed away on May 12, 2017 Background: A large percentage (16% of maternal mortality in developed countries, compared to 9% in developing countries, is due to hypertensive disorders in pregnancy. The etiology of preeclampsia remains unknown, with poorly understood pathophysiology. Magnesium and calcium play an important role in vascular smooth muscle function and therefore a possible role in the development of preeclampsia.Aim: We aimed to compare serum magnesium and total calcium levels of preeclamptic and normal pregnant women at the Korle-Bu Teaching Hospital in Ghana.Patients and methods: A comparative cross-sectional study involving 30 normal pregnant and 30 preeclamptic women with >30 weeks gestation and aged 18–35 years, was conducted at the Korle-Bu Teaching Hospital. Magnesium and calcium were determined using a flame atomic absorption spectrometer.Results: Mean serum magnesium and total calcium levels in preeclamptic women were 0.70±0.15 and 2.13±0.30 mmol/L, respectively. Mean serum magnesium and total calcium levels in normal pregnant women were 0.76±0.14 and 2.13±0.35 mmol/L, respectively. There was a statistically nonsignificant difference in serum magnesium and total calcium in preeclamptic women compared to normal pregnant women, with p-values of 0.092 and 0.972, respectively.Conclusion: Serum magnesium and total calcium, therefore, seem not to differ in preeclamptic women compared to normal pregnant women in Ghana

EGE BÖLGESİNDEKİ İLLERDE PENCERELER İÇİN OPTİMUM HAVA TABAKASI KALINLIĞININ ARAŞTIRILMASI

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Ali Keçebaş

2016-06-01

Full Text Available Bu çalışmada Ege Bölgesi’ndeki sekiz (Manisa, İzmir, Kütahya, Uşak, Afyon, Aydın, Denizli, Muğla il için düşey konumda iki cam plaka arasındaki hava tabakası 1 mm’den başlayıp 280 mm’ye kadar hava boşluğunun penceredeki yalıtıma etkileri araştırılmıştır. Araştırma sonuçlarına göre; Ege Bölgesi’ndeki iller için pencerelerde optimum hava boşluğu yaklaşımı getirilmiştir. Bu yaklaşımla İzmir’de 14 mm, Denizli’de 13 mm, Uşak’ta 12,5 mm ve dış hava sıcaklığı aynı olan üç ilde (Aydın, Manisa, Muğla 13,4 mm ve iki ilde (Afyon, Kütahya 12,2 mm olarak optimum hava tabakası kalınlığı hesaplanmıştır. Bu çalışma ile literatüre Ege Bölgesi’ndeki her il için optimum hava tabakası kalınlığı yaklaşımı getirilmiştir.

Pre-emptif uygulanan intravenöz, spinal ve epidural morfinin erken postoperatif analjezi ve stres yanıt üzerine etkileri

OpenAIRE

Düger, Cevdet; Ayvaz, Hakan; Bulut, Filiz; Gürsoy, Sinan; Kaygusuz, Kenan; İsbir, Ahmet Cemil; Özdemir Kol, İclal; Gürelik, Bilge; Mimaroğlu, Caner

2013-01-01

Özet Bu çalışmada, preemptif uygulanan iv, spinal ve epidural morfinin erken postoperatif dönemdeki analjezik tüketimi ve stres yanıt üzerine etkilerini belirlemek amaçlandı. Alt batın operasyonu uygulanacak ASA I-II grubuna giren 60 hasta rasgele üç gruba ayrıldı. Grup I’e indüksiyondan 5 dk. önce 5 mg iv morfin, Grup II’ye indüksiyondan 5 dk önce 0,5 mg intratekal morfin, Grup III’e indüksiyondan 30dk önce 5mg epidural morfin uygulandı. Anestezi indüksiyonu 0,1 µg kg-1 fentanil ve 4-7 mg k...

KARDİYOVASKÜLER HASTALIKLARA İLİŞKİN TÜRKİYE TIBBI CİHAZ SEKTÖRÜ YOĞUNLAŞMA ANALİZİ

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Faruk KAHVECİOĞLU

2016-08-01

Full Text Available Dünya genelinde kardiyovasküler hastalıklara bağlı ölümler birinci sırada yer almaktadır, bu durum ilgili hastalıkların tanısı, izlenmesi ve tedavisi amacıyla kullanılan tıbbi cihazların önemini arttırmaktadır. Sağlık harcamaları açısından bakıldığında ise sektördeki teknoloji yoğun üretim artışı ile birlikte son yıllarda bu sektörün sağlık harcamaları içindeki payının artmakta olduğu görülmektedir Bu durum sağlık sektöründe en büyük aktör olan (Sunum ve Finansman kamu kesiminin piyasa üzerinde fiyat ve miktar gibi kısıtlamalar ile müdahalesi sonucunu doğurmaktadır. Çalışmamızda N-Firma Yoğunlaşma Oranı ve Herfindal-Hirschman Endeksi analizi yöntemi kullanılarak 2013-2014 yıllarında Türkiye Kardiyovasküler hastalıklara ilişkin tıbbi cihaz sektörünün yoğunlaşma analizi yapılmıştır. CR4 analizi sonucuna göre piyasanın oligopolistik bir yapı sergilediği ve sektöre yönelik pozitif liste uygulamalarının hayata geçirildiği yıllarda bu yapının güçlendiği gözlemlenmiştir. HHI yoğunlaşma analizine göre de 2013 yılında sektör az yoğun piyasa görünümüne sahipken, 2014 yılında ise piyasanın az yoğun yapısının çok yoğun olarak değiştiği görülmüştür.

Tautas partijas reklāmas un sabiedrisko attiecību kampaņas pirms 7. un 9. Saeimas vēlēšanām

OpenAIRE

Velika, Anna

2007-01-01

Tautas partija tika nodibināta 1998.gada maijā, īsi pirms 7.Saeimas vēlēšanām. Pateicoties harizmātiskajam līderim A.Šķēlem, masīvai reklāmas un sabiedrisko attiecību kampaņai, kā arī tautas uzticībai un cerībām jaunā partija gūst uzvaru vēlēšanās. Taču uzmanību piesaista fakts, ka šī partija, kas ir neraksturīgi pašreizējai Latvijas politiskajai skatuvei, spēj iekarot stabilu vietu gan valdībā, gan pašvaldībās, un ar profesionālu kampaņu palīdzību gūt panākumus arī divās nākamajās Saeimas vē...

Sabiedriskās attiecības jauno reliģisko kustību praksē. Baznīcas "Jaunā paaudze" gadījuma analīze

OpenAIRE

Maļuha, Sandra

2008-01-01

Izstrādātā bakalaura darba nosaukums ir „Sabiedriskās attiecības jauno reliģisko kustību praksē: baznīcas „Jaunā paaudze” gadījuma analīze”. Darbā aplūkotā pētnieciskā problēma ir jauns, līdz šim maz pētīts fenomens - sabiedrisko attiecību mērķu realizācija jauno reliģisko kustību darbībā. Izvēlētais pētniecības objekts ir baznīca „Jaunā paaudze”, kura, pēc Tieslietu ministrijas Reliģisko lietu pārvaldes sniegtajiem datiem, šobrīd ir lielākā jaunā reliģiskā kustība Latvijā. Teorētiskā pama...

TÜRKİYE’NİN AB’YE ÜYELİK SÜRECİNİN MALİ GÖSTERGELER AÇISINDAN AB’NİN YENİ ÜYE ÜLKELERİYLE KARŞILAŞTIRILMASI

OpenAIRE

YAVUZ, Hakan; YAVUZ, Sinem

2015-01-01

Türkiye’nin Avrupa Birliği (AB) ile ilişkisi uzun bir tarihsel geçmişe dayanmasına rağmen, halen nihai hedefine ulaşamamıştır. Ancak tam üyelik yolunda önemli adımların atıldığı söylenebilir. Söz konusu gelişmelere paralel olarak, Türkiye-AB ilişkilerine yönelik literatür de genişlemektedir. Literatürde bazı çalışmalar ilişkinin ekonomik, mali, bazı çalışmalar da siyasi, kültürel ve sosyal boyutunu ele almaktadır. Bu çalışmanın amacı, Türkiye’nin AB üyelik sürecinin mali göstergelere gösterdi...

TÜRKİYE HAVAYOLU YOLCU TAŞIMACILIĞI SEKTÖRÜNDE HİZMET KALİTESİNİN KARŞILAŞTIRMALI ÖLÇÜMLENMESİ

Directory of Open Access Journals (Sweden)

Oğuz YILDIZ

2013-02-01

Full Text Available Yeni müşteriler kazanmak ve mevcut müşterileri elde tutmak bir süredir hizmet işletmeleri için iki önemli konu olmuştur. Hizmetin her aşamasında fark yaratmak bu iki amacın başarılmasında anahtar bir etkendir. Hizmet sunumunun farklılaştırılması açısından hizmet kalitesi göz önüne alındığında, müşterilere sağlanan hizmetin kalitesini ölçmenin önemi ortaya çıkmaktadır. Hizmet işletmeleri için hizmet kalitesini ölçmek zor bir konudur çünkü hizmet soyuttur, değişkendir, dayanıksızdır ve son olarak hizmetin üretimi ve tüketimi aynı anda gerçekleşmektedir. Hizmet kalitesinin ölçümü işletmelere pazarlama faaliyetlerini nasıl yönetecekleri bilgisini sağlar. Bu nedenle bu ölçme işlemi doğru ölçeklerle yapılmalıdır. Bu çalışmada ilk olarak hizmet kalitesi yazınsalı incelenmiş daha sonra yüz yüze anket yöntemiyle araştırmaya temel teşkil edecek veriler toplanmıştır. Araştırmada son olarak, keşifsel faktör analizi yapılmış ve hizmet kalitesini ölçen iki model karşılaştırılmıştır. Araştırmadaki bulgular, ağırlıklı SERVPERF ölçeğinin algılanan hizmet kalitesini ağırlıklı SERVQUAL ölçeğinden daha fazla açıkladığını ortaya koymuştur.

Instrumentation of the model in scaled 1:10 to prototype of the AquaBuOY wave energy converter

DEFF Research Database (Denmark)

Margheritini, Lucia; Frigaard, Peter

The objective of this report is to provide guidelines for the instrumentation of a model in scale 1:10 to prototype of the AquaBuOY wave energy converter. The model will be located in Nissum Bredning area: this is an important waterway already used by Aalborg University for real sea tests of wave...... energy converters....

Transition-Metal-Free C-Vinylation of Ketones with Acetylenes: A Quantum-Chemical Rationalization of Similarities and Differences in Catalysis by Superbases MOH/DMSO and tBuOM/DMSO (M = Na, K).

Science.gov (United States)

Orel, Vladimir B; Vitkovskaya, Nadezhda M; Kobychev, Vladimir B; Trofimov, Boris A

2018-04-06

Transition-metal-free C-vinylation of acetone with phenylacetylene catalyzed by superbases MOH/DMSO and tBuOM/DMSO (M = Na, K) has been theoretically evaluated in the B3LYP/6-311++G**//B3LYP/6-31+G* approach to rationalize similarities and differences in activity of the above catalytic systems. The close solvate surroundings of sodium and potassium tert-butoxides have been studied. Formation of tBuOM· nDMSO complexes and their structure and thermodynamic stability are discussed in comparison with similar complexes of alkali-metal hydroxides MOH· nDMSO. Activation barriers of the title reaction in the presence of tBuOM· nDMSO complexes are found to be less than those with MOH· nDMSO complexes participating.

Appropriateness and diagnostic yield of referrals for oesophagogastroduodenoscopy at the Korle Bu Teaching Hospital.

Science.gov (United States)

Tachi, K; Nkrumah, K N

2011-01-01

Increasing endoscopy workload in open-access services necessitates adoption of appropriateness criteria to check abuse and improve yield. To assess the appropriateness of referrals for oesophagogastroduodenoscopy (OGD) and its relationship to yield at Korle-Bu Teaching Hospital (KBTH), Accra. Referrals, signs, and symptoms of 375 consecutive patients for diagnostic oesophagogastroduodenoscopy were evaluated over four months. Indications were categorized as appropriate or inappropriate using the American Society of Gastrointestinal Endoscopy (ASGE) guidelines and endoscopic findings (yield) categorized as positive or negative. The relationship between these was analyzed and the diagnostic accuracy of the guidelines determined. There were 209 (55.7%) females, and 316 (84.3%) open-access procedures. Mean age was 46±17 years. Dyspepsia, 272 (72.5%) and epigastric tenderness, 192 (41.4 %) were the commonest symptom and sign respectively. Only 133 (35.5%) reported alarm symptoms. Appropriate referrals constituted 221(58.9%). Inappropriate referral rate was similar for endoscopists and non-endoscopists. Positive yield was 62.7%. Male sex, age > 45 years, haematemesis, persistent vomiting, gastroenterologists' referrals and epigastric tenderness were the best predictors of positive yield. Gastritis, 121 (32.3%), duodenal ulcer, 48 (12.5%) and oesophagitis, 36 (9.6%) were the leading endoscopy diagnoses. Carcinomas were reported only after 45 years and 18 (81.8%) of the cases had alarm symptoms. Inappropriate referral for OGD rate is high in Accra. Yield is improved by adherence to the ASGE guidelines but its accuracy as a screening tool for OGD at Korle- Bu Teaching Hospital is too low to recommend it for adoption.

Luis Buñuel: el fantasma de la libertad entre el instinto y la risa

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Eduardo Peñuela Cañizal

2008-06-01

Full Text Available Os temas abordados por Buñuel nos são bem conhecidos, mas o que é importante em seus filmes é a maneira de apresentar esses temas através da mistura de elementos racionais e irracionais. Para o diretor espanhol o cinema é um instrumento de poesia e, nessa perspectiva, ele desenvolve modalidades de escrita destinadas a expressar todo tipo de significações libertárias. Neste artigo se borda uma dessas maneiras de escrita cinematográfica.

Oral tumours seen at Korle Bu Teaching Hospital: a preliminary report

International Nuclear Information System (INIS)

Parkins, G.; Armah, G.E.; Tetteh, Y.

2002-01-01

Oral tumours in patients attending the oral Surgery Department of the Korle Bu Teaching Hospital, Accra, during a 12 month period from February 1998 to January 1999 were studied and classified. In all, 50 patients were included in the study out of which 33 were fully characterised and classified historically. Fifteen (45.4%) of the tumours examined were squamous cell carcinoma (SCC), 6(18.2%) ameloblastoma (AME), 3 (9.1%) each of Lympoma (L), adenoid cystic carcinoma (ADC) and pleomorphic adenoma (PA), 2(61.1%) ossifying fibroma (OF) and 1(3.0%) embryonal rhabdomyosar coma (ER). There was significant observed between the prevalence rates in men and women. OSCC was found to occur more frequently in the palate/maxillary sinus and the parotid gland whilst ameloblastoma was the commonest benign neoplasm within the fourth decade. (author)

Allah’ın Varlığını Aklen Bilmeye İlişkin Mâtürîdî'nin Gâye ve Nizam Delili / The Argument of “Hikmah and Tadbir” to Prove The Existence of God According to al-Maturidi

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Fatma Aygün

2015-05-01

Full Text Available Öz Mâtürîdî İslâm düşünce tarihinde önemli bir yere sahip bulunan düşünürlerden biridir. Öyle ki Mâtürîdî (333/944 Ebû Hanîfe geleneğinin en güçlü simasıdır ve Ehl-i Sünnet kelâmının kuruluşunda en büyük paya sahiptir. Mâtürîdî'nin düşüncesinde "hikmet" ve "tedbîr" kavramları çok önemli bir yere sahiptir, o Allah'ın varlığını bilmek için hikmet ve tedbîr terimleriyle ilşkilendirdiği gâye ve nizam delilini kullanmıştır. Ayrıca o kötülük (şer olarak gördüğümüz şeyler dahil var olan tüm şeylerin "hikmet"in bir tezahürü olarak ortaya çıktığından bahsetmiştir. Mâtürîdî'nin düşünce sisteminde Allah'ın varlığı bilmek için kullanılan teleolojik delil ki doğadaki düzenlilik, güzellik ve tedbirin gözlemlerinden, analojik veya endüktif muhakemenin bazı türleri aracılığıyla ilerler, sonuç olarak bunlar bir tasarımcının (Allah işi olmalıdır. Bu Makalede gâye ve nizam delili ile ilgili Mâtürîdî'nin evrendeki düzeni ispat etmeye yönelik ortaya koymuş olduğu argümanlar ayrı başlıklar halinde ele alınmış ve tartışılmıştır. Anahtar Kelimeler: Kelâm, Mâtürîdî, Allah'ın Varlığının Delilleri, Hikmet, Tedbîr, Gâye ve Nizâm Delili (Teleolojik Delil. The Argument of “Hikmah and Tadbir” to Prove The Existence of God According to al-Maturidi Abstract Al-Maturidi is one of the foremost and most important thinkers in the history of Islamic thought. So that al-Maturidi (333/944 is the most powerful figure in Ebû Hanîfe School and has the biggest share in the establishment of Followers of Sunnah kalam. The "hikmah" (wisdom and "tadbir" (order concepts are very important terms in the thought of al-Maturidi. He used the argument of “aim and order" (teleological argument -that he links with the term hikmah and tadbir- to prove the existence of God. He also stated that all things, including even the bad things (malignity, come

Ethylene homo- and copolymerization chain-transfers: A perspective from supported (n BuCp) 2 ZrCl 2 catalyst active centre distribution

KAUST Repository

Atiqullah, Muhammad; Al-Harthi, Mamdouh A.; Anantawaraskul, Siripon; Emwas, Abdul-Hamid M.

2015-01-01

/MAO/(nBuCp)2ZrCl2 - were applied to evaluate the active-centre-dependent ethylene homo- and copolymerization rates, as well as the corresponding chain termination rates. This approach, from a microkinetic mechanistic viewpoint, elucidates better the 1-hexene

Sequence stratigraphy and environmental background of the late Pleistocene and Holocene occupation in the Southeast Primor'ye (the Russian Far East)

Science.gov (United States)

Chlachula, Jiri; Krupyanko, Alexander A.

2016-06-01

The paper presents the results of Quaternary palaeoecology and geoarchaeology studies in the Zerkal'naya Basin, with new insights about sequenced natural shifts during the prehistoric occupation of this marginally explored NE Asian maritime territory. The Basin is part of the continental drainage system and the main physiographic and biotic corridor for peopling of the transitive coastal interior SE Primor'ye Region. The Final Pleistocene and Holocene environmental (biotic and abiotic) proxy records from the Upper/Final Palaeolithic to early historical sites document a dynamic climate change with vegetation cover transformations within riverine and mountain valley ecosystems of the Russian Far East. Most of the archaeological sites located on the low terraces and bedrock promontories along the main river channel and its tributary streams suggest traditional hunter gathered lifestyles based on seasonal salmon-fishing supplemented by pastoral economy. Tundra-forests with larch trees, dwarf birch thickets and polypod ferns from the basal stratigraphic units of the late Last Glacial occupation sites associated with the Upper Palaeolithic micro-blade and bifacial stone tool traditions (14C-dated to 19,000-12,000 cal yrs BP) indicate rather pronounced conditions and much lower MAT comparing today. Following a final Pleistocene cooling event, a major climate warming marked the onset of Holocene accompanied by a regional humidity increase promoting the formation of a mixed broadleaved-coniferous oak-dominant taiga, and culminating in the mid-Holocene Climatic Optimum. The appearance of mosaic parklands ca. 5,000-4,000 cal yrs BP. may be partly attributed to the expansion of the Far Eastern Neolithic cultures practicing forest clearance for pastures and dwellings. A progressing landscape opening indicated by the spread of light-demanding thickets and birch-dominated riverine biotopes with Artemisia suggests a further vegetation cover transformation during the late Neolithic

Çevresel Kuznets Eğrisi Hipotezi: Türkiye İçin Eşbütünleşme ve Nedensellik Analizi

Directory of Open Access Journals (Sweden)

Fuat LEBE

2016-07-01

Full Text Available Bu çalışmanın amacı, Türkiye’nin 1960-2010 dönemi için Çevresel Kuznets Eğrisi (EKC hipotezinin geçerliliğini test etmektir. Değişkenler arasındaki ilişki ARDL sınır testi ile Granger nedensellik testiyle araştırılmıştır. Analiz sonucu, EKC hipotezinin Türkiye için geçerli olduğu ve özellikle enerji tüketimi (EC, finansal gelişme (FD ve dışa açıklığın (OP karbondioksit (CO2 emisyonunu arttırdığı tespit edilmiştir. Nedensellik testi sonucuna göre, kısa dönemde FD’den CO2 emisyonuna, EC’ye ve GDP’ye doğru tek yönlü nedensellik belirlenmiştir. Uzun dönemde ise CO2 emisyonu ile EC, CO2 emisyonu ile ekonomik büyüme (EG ve CO2 emisyonu ile FD arasında feed-back (geri-besleme hipotezini doğrulayan bulgular elde edilmiştir.

Jaunā komunikācijas pieeja klientu attiecību pārvaldībai viesnīcu nozarē

OpenAIRE

Sandra Marianne Heiden

2014-01-01

ANOTĀCIJA “Visas uzņēmējdarbības pamatā ir attiecības. Uzņēmumam tikai tās saviem klientiem jāpadara uztveramas un jēgpilnas - ar nosacījumu, ka klienti to vēlas” (Grönroos 2007, 24 lpp.). Uzņēmuma spēja palielināt apgrozījumu, izmantojot efektīvu vadību attiecībās ar klientiem ir ļoti svarīga, lai pārvarētu ekonomisko nenoteiktību visā pasaulē. Jaunās digitālo mediju īpašības kopā ar milzīgu alternatīvo paņēmienu klāstu saziņai ar klientiem ir radījušas vadītājiem un akadēmiķiem gan iespē...

Polyoxygenated Cyclohexenoids with Promising α-Glycosidase Inhibitory Activity Produced by Phomopsis sp. YE3250, an Endophytic Fungus Derived from Paeonia delavayi.

Science.gov (United States)

Huang, Rong; Jiang, Bo-Guang; Li, Xiao-Nian; Wang, Ya-Ting; Liu, Si-Si; Zheng, Kai-Xuan; He, Jian; Wu, Shao-Hua

2018-02-07

Seven new polyoxygenated cyclohexenoids, namely, phomopoxides A-G (1-7), were isolated from the fermentation broth extract of an endophytic fungal strain Phomopsis sp. YE3250 from the medicinal plant Paeonia delavayi Franch. The structures of these compounds were established by spectroscopic interpretation. The absolute configurations of compounds 1 and 4 were confirmed by X-ray crystallographic analysis and chemical derivative approach. All isolated compounds showed weak cytotoxic activities toward three human tumor cell lines (Hela, MCF-7, and NCI-H460) and weak antifungal activities against five pathogenic fungi (Candida albicans, Aspergillus niger, Pyricularia oryzae, Fusarium avenaceum, and Hormodendrum compactum). In addition, compounds 1-7 showed a promising α-glycosidase inhibitory activity with IC 50 values of 1.47, 1.55, 1.83, 2.76, 2.88, 3.16, and 2.94 mM, respectively, as compared with a positive control of acarbose (IC 50 = 1.22 mM).

Paterno`-Bu¨chi Reaction as a Demonstration of Chemical Kinetics and Synthetic Photochemistry Using a Light Emitting Diode Apparatus

Science.gov (United States)

Thompson, Matthew P.; Agger, Jonathan; Wong, Lu Shin

2015-01-01

The Paterno`-Bu¨chi photocycloaddition reaction is used as the basis for physical-organic final-year undergraduate laboratory experiments designed to emphasize the multidisciplinary approach to modern-day chemical practice. These reactions are performed using commercially available LED-based light sources, which offer a convenient and safe tool…

Effects of supported (nBuCp)2ZrCl2 catalyst active center multiplicity on crystallization kinetics of ethylene homo- and copolymers

KAUST Repository

Atiqullah, Muhammad; Adamu, Sagir; Hossain, Mohammad Mozahar; Al-Harthi, Mamdouh A.; Anantawaraskul, Siripon; Hossaen, Anwar

2014-01-01

Two different supported zirconocene, that is, bis(n-butylcyclopentadienyl) zirconium dichloride (nBuCp)2ZrCl2, catalysts were synthesized. Each catalyst was used to prepare one ethylene homopolymer and one ethylene-1-hexene copolymer. Catalyst

Fibreoptic gastro-intestinal endoscopy at the Korle Bu Teaching Hospital, Accra, Ghana: a historical perspective.

Science.gov (United States)

Nkrumah, Kofi N; Archampong, Emmanuel Q

2017-12-01

Fibreoptic (or Flexible) endoscopy has revolutionized and completely transformed practice of gastroenterology, and many other medical specialties, over the past half century or so. At the Korle Bu Teaching Hospital, Accra the development of this facility has evolved gradually, especially involving specialists from the Departments of Medicine and Surgery since the 1970s. This article is an attempt to trace and record this journey and to highlight some of the problems and challenges yet to be overcome. It is an anecdotal account based on the authors' recollection with attempts at verification of important dates.

Antipsychotic-like effect of the muscarinic acetylcholine receptor agonist BuTAC in non-human primates

DEFF Research Database (Denmark)

Andersen, Maibritt B; Croy, Carrie Hughes; Dencker, Ditte

2015-01-01

Cholinergic, muscarinic receptor agonists exhibit functional dopamine antagonism and muscarinic receptors have been suggested as possible future targets for the treatment of schizophrenia and drug abuse. The muscarinic ligand (5R,6R)-6-(3-butylthio-1,2,5-thiadiazol-4-yl)-1-azabicyclo[3.2.1]octane...... (BuTAC) exhibits high affinity for muscarinic receptors with no or substantially less affinity for a large number of other receptors and binding sites, including the dopamine receptors and the dopamine transporter. In the present study, we wanted to examine the possible antipsychotic-like effects...

Exploring the use of smartphones and tablets by medical House Officers in Korle-Bu Teaching Hospital.

Science.gov (United States)

Barnor-Ahiaku, Edem

2016-03-01

Smartphones and tablets are being used widely in the Western World creating benefits in healthcare. The Ministry of Health in Ghana has an e-Health strategy, with the aim of integrating such resources into healthcare. Whilst there are numerous mHealth projects going on in Ghana, there is little evidence of doctors using such devices in their practice. A qualitative study was undertaken in Korle-Bu Teaching Hospital. Random sampling was used to identify House Officers, who engaged in semi-structured interviews. Interviews were recorded, transcribed and analysed using thematic content analysis. Consent was gained from all participants and the University of Leeds granted ethical approval. The results demonstrate that current House Officers began using smartphones and tablets at various stages during medical school. Their use has increased since qualification. Although the overall use has increased, some staff remain resistant to the use of smartphones and tablets. In the future, the integration of smartphones and tablets into medical practice can be improved by integration with the medical curriculum and accepted practice. House Officers are routinely using smartphones and tablets to assist them in their daily practice. The use is informal and is peer led. Whilst they bring many benefits, there are issues, which need to be addressed. In Korle-Bu Teaching Hospital integrating smartphone and tablet use into practice is feasible and would prove beneficial.

TANIMLANMIŞ FAYDA PLANLARININ 1 NOLU TÜRKİYE MUHASEBE STANDARDI ÇERÇEVESİNDE MUHASEBELEŞTİRİLMESİ VE ORTAYA ÇIKARDIĞI İKTİSADİ SONUÇLAR

Directory of Open Access Journals (Sweden)

Mustafa OĞUZ

2016-02-01

Full Text Available İşletmelerde çalışan kişiler işletmelere sunmuş oldukları hizmetler karşılığında gelecekte çeşitli faydalar sağlamayı beklemektedir. Çalışanların gelecekte sağlayacakları bu faydalara ilişkin olarak iş- letmelerin yükümlülükleri doğmaktadır. Çalışanlar tarafından işletmelere sunulan hizmetler nedeniyle veya iş ilişkisinin sona erdirilmesi dolayısıyla işletmeler tarafından sağlanan her türlü bedel çalışanlara sağlanan faydalar olarak tanımlanmaktadır. Çalışanlara sağlanan faydalara yönelik hesaplamalar ve bunların muhasebeleştirilmesi işletmeler açısından oldukça önem arz etmektedir Bu sebeple, çalışanlara sağlanan faydalar konusu ulusal ve uluslararası birçok muhasebe ve finansal raporlama standardında ele alınmaktadır. Bu konu, Türkiye’de TMS 19 Çalışanlara Sağlanan Faydalar Standardı’nda ele alınmaktadır. Bu çalışmada, TMS 19 kapsamındaki tanımlanmış fayda planlarının muhasebeleştirilmesi üzerinde durulmakta olup, söz konusu fayda planlarının muhasebeleştirilmesinde gerçeğe uygun değer esasının kullanılmasının ortaya çıkardığı iktisadi sonuçlar ele alınmaktadır.

Alteration of radiation-induced hematotoxicity by Bu-Zhong-Yi-Qi-Tang in mouse

International Nuclear Information System (INIS)

Jang, Jong Sik; Kim, Sung Ho

2008-01-01

The purpose of this study reported here was to investigate the ability of Bu-Zhong-Yi-Qi-Tang (BZYQT), known to elevate hematopoietic functions, to protect mice undergoing treatment with whole body single gamma-irradiation. BZYQT was given (25 mg/kg B.W.) intraperitoneally at 36 and 12 hours before irradiation and 30 minute and 24 hours after irradiation. Recovery of neutrophil and lymphocyte counts was significantly stimulated by extract of BZYQT. Stimulated recovery by the extract from the BZYQT was also observed in thrombocytes. However, the anti-radiation effect of erythrocyte, hemoglobin and hematocrit was not as significant as that of leukocyte. Further studies are needed to better characterize the protective nature of BZYQT extract and its ingredients

Alteration of radiation-induced hematotoxicity by Bu-Zhong-Yi-Qi-Tang in mouse

Energy Technology Data Exchange (ETDEWEB)

Jang, Jong Sik [Kyungpook National University, Daegu (Korea, Republic of); Kim, Sung Ho [Chonnam National University, Gwangju (Korea, Republic of)

2008-09-15

The purpose of this study reported here was to investigate the ability of Bu-Zhong-Yi-Qi-Tang (BZYQT), known to elevate hematopoietic functions, to protect mice undergoing treatment with whole body single gamma-irradiation. BZYQT was given (25 mg/kg B.W.) intraperitoneally at 36 and 12 hours before irradiation and 30 minute and 24 hours after irradiation. Recovery of neutrophil and lymphocyte counts was significantly stimulated by extract of BZYQT. Stimulated recovery by the extract from the BZYQT was also observed in thrombocytes. However, the anti-radiation effect of erythrocyte, hemoglobin and hematocrit was not as significant as that of leukocyte. Further studies are needed to better characterize the protective nature of BZYQT extract and its ingredients.

Olimpiyatlara ev sahipliği yapacak olan kentlerde aranan kiriterlerin peyzaj mimarlığı açısından değerlendirilmesi

OpenAIRE

BANİNOSRAT, Nede

2011-01-01

Olimpiyat Oyunları, ülkeleri karşı karşıya getiren dünyanın en büyük spor organizasyonudur. Olimpiyat organizasyonu ile birlikte şehrin ve ülkenin imajının, ekonomisinin, turizm ve spor imkanlarının daha iyi yönde gelişme göstermesi ülkelerin ilgisinin Olimpiyatlara yönelmesini sağlamıştır.Yaz Olimpiyatları için Sidney Olimpiyat Komitesi (SOCOG) ?yeşil olimpiyat? parolasıyla birtakım çevresel ilkeler belirlemiştir. Bu ilkeler, sürdürülebilir gelişim ve çevreye duyarlı yön...

Evaluation of 11C-BU99008, a positron emission tomography ligand for the Imidazoline2 binding site in human brain.

Science.gov (United States)

Tyacke, Robin J; Myers, Jim F M; Venkataraman, Ashwin; Mick, Inge; Turton, Samuel; Passchier, Jan; Husbands, Stephen M; Rabiner, Eugenii Ilan A; Gunn, Roger N; Murphy, Philip S; Parker, Christine A; Nutt, David J

2018-03-09

The imidazoline 2 binding site (I 2 BS), are thought to be expressed in glia, and implicated in the regulation of glial fibrillary acidic protein. A PET ligand for this target would be important for the investigation of neurodegenerative and neuroinflammatory diseases. 11 C-BU99008 has previously been identified as a putative PET radioligand. Here we present the first in vivo characterisation of this PET radioligand in humans and assess its test-retest reproducibility. Methods 14 healthy male volunteers underwent dynamic PET imaging with 11 C-BU99008 and arterial sampling. Six subjects were used to assess test-retest and eight were used in the pharmacological evaluation, undergoing a second, or third heterologous competition scan with the mixed I 2 BS/α 2 -adrenoceptor drug, idazoxan (n=8; 20, 40, 60 and 80mg) and the mixed irreversible MAO A/B inhibitor, isocarboxazid (n=4; 50mg), respectively. Regional time-activity data were generated from arterial plasma input functions corrected for metabolites using the most appropriate model to derive the outcome measure V T (regional total distribution volume). All image processing and kinetic analysis was performed in MIAKAT™ (www.miakat.org). Results Brain uptake of 11 C-BU99008 was good with reversible kinetics and a heterogeneous distribution consistent with known I 2 BS expression. Model selection criteria indicated that the 2-tissue-compartment was preferred. V T estimates were high in the striatum (113±20 mL·cm -3 ), medium in cortex frontal lobe (55±9 mL·cm -3 ) and low in the cerebellum (47±7 mL·cm -3 ). Test-retest reliability was found to be reasonable. The uptake was dose-dependently reduced by pre-treatment with idazoxan throughout the brain, with an average block across all regions of ~60% ( V T = ~30 mL·cm -3 ) at the highest dose (80 mg). The ED 50 for idazoxan was calculated as 33.1 mg. Uptake was not blocked by pre-treatment with the MAO inhibitor, isocarboxazid. Conclusions In summary, 11 C-BU

TÜRKİYE İÇİN İŞ-AİLE DENGESİ ÖLÇEĞİNİN ALT BOYUTLARI VE BELİRLEYİCİLERİ

OpenAIRE

GÜLER, Hüseyin; GÜLER, Ebru ÖZGÜR

2015-01-01

Bu çalışmanın amacı İş-Aile Dengesi Ölçeğinin (Work-Family Balance Scale, WFBS)faktör yapısını ortaya çıkarmak ve bu ölçeğin Türkiye’deki geçerlilik ve güvenilirliğinibelirlemektir. Ölçek, istatistiki bölge kavramında kullanılmakta olan, 1. Düzeydeki 12İstatistiki Bölgede yaşayan 682 vatandaştan oluşan bir örneklem üzerinde uygulanmıştır.Orijinal halinde 26 ifade bulunan “İş-Aile Kısıtları” ve “İş-Aile Kazanımları” ölçeği, işailedengesini ölçmek amacıyla kullanılan uygun bir ölçektir. Daha ön...

By their words ye shall know them: evidence of genetic selection against general intelligence and concurrent environmental enrichment in vocabulary usage since the mid 19th century

Directory of Open Access Journals (Sweden)

Michael Anthony Woodley of Menie

2015-04-01

Full Text Available It has been theorized that declines in g due to negative selection stemming from the inverse association between completed fertility and IQ, and the Flynn effect co-occur, with the effects of the latter being concentrated on less-heritable non-g sources of intelligence variance. Evidence for this comes from the observation that 19th Century populations were more intellectually productive, and also exhibited faster simple reaction times than modern ones, suggesting higher g. This co-occurrence model is tested via examination of historical changes in the utilization frequencies of words from the highly g-loaded WORDSUM test across 5.9 million texts spanning 1850 to 2005. Consistent with predictions, words with higher difficulties (δ parameters from Item Response Theory and stronger negative correlations between pass-rates and completed fertility presented a steeper decline in use over time, than less difficult and less negatively selected words, which increased in use over time, suggestive of a Flynn effect. These findings persisted when explicitly controlled for word age, literacy rates and temporal autocorrelation. These trends constitute compelling evidence that both producers and consumers of text have experienced declines in g since the mid-19th Century.

Silica-supported (nBuCp)2ZrCl2: Effect of catalyst active center distribution on ethylene-1-hexene copolymerization

KAUST Repository

Atiqullah, Muhammad

2013-08-12

Metallocenes are a modern innovation in polyolefin catalysis research. Therefore, two supported metallocene catalysts-silica/MAO/(nBuCp)2ZrCl2 (Catalyst 1) and silica/nBuSnCl3/MAO/(nBuCp)2ZrCl2 (Catalyst 2), where MAO is methylaluminoxane-were synthesized, and subsequently used to prepare, without separate feeding of MAO, ethylene-1-hexene Copolymer 1 and Copolymer 2, respectively. Fouling-free copolymerization, catalyst kinetic stability and production of free-flowing polymer particles (replicating the catalyst particle size distribution) confirmed the occurrence of heterogeneous catalysis. The catalyst active center distribution was modeled by deconvoluting the measured molecular weight distribution and copolymer composition distribution. Five different active center types were predicted for each catalyst, which was corroborated by successive self-nucleation and annealing experiments, as well as by an extended X-ray absorption fine structure spectroscopy report published in the literature. Hence, metallocenes impregnated particularly on an MAO-pretreated support may be rightly envisioned to comprise an ensemble of isolated single sites that have varying coordination environments. This study shows how the active center distribution and the design of supported MAO anions affect copolymerization activity, polymerization mechanism and the resulting polymer microstructures. Catalyst 2 showed less copolymerization activity than Catalyst 1. Strong chain transfer and positive co-monomer effect-both by 1-hexene-were common. Each copolymer demonstrated vinyl, vinylidene and trans-vinylene end groups, and compositional heterogeneity. All these findings were explained, as appropriate, considering the modeled active center distribution, MAO cage structure repeat units, proposed catalyst surface chemistry, segregation effects and the literature that concerns and supports this study. While doing so, new insights were obtained. Additionally, future research, along the direction

Silica-supported (nBuCp)2ZrCl2: Effect of catalyst active center distribution on ethylene-1-hexene copolymerization

KAUST Repository

Atiqullah, Muhammad; Anantawaraskul, Siripon; Emwas, Abdul-Hamid M.; Al-Harthi, Mamdouh Ahmed; Hussain, Ikram; Ul-Hamid, Anwar; Hossaen, Anwar

2013-01-01

Metallocenes are a modern innovation in polyolefin catalysis research. Therefore, two supported metallocene catalysts-silica/MAO/(nBuCp)2ZrCl2 (Catalyst 1) and silica/nBuSnCl3/MAO/(nBuCp)2ZrCl2 (Catalyst 2), where MAO is methylaluminoxane-were synthesized, and subsequently used to prepare, without separate feeding of MAO, ethylene-1-hexene Copolymer 1 and Copolymer 2, respectively. Fouling-free copolymerization, catalyst kinetic stability and production of free-flowing polymer particles (replicating the catalyst particle size distribution) confirmed the occurrence of heterogeneous catalysis. The catalyst active center distribution was modeled by deconvoluting the measured molecular weight distribution and copolymer composition distribution. Five different active center types were predicted for each catalyst, which was corroborated by successive self-nucleation and annealing experiments, as well as by an extended X-ray absorption fine structure spectroscopy report published in the literature. Hence, metallocenes impregnated particularly on an MAO-pretreated support may be rightly envisioned to comprise an ensemble of isolated single sites that have varying coordination environments. This study shows how the active center distribution and the design of supported MAO anions affect copolymerization activity, polymerization mechanism and the resulting polymer microstructures. Catalyst 2 showed less copolymerization activity than Catalyst 1. Strong chain transfer and positive co-monomer effect-both by 1-hexene-were common. Each copolymer demonstrated vinyl, vinylidene and trans-vinylene end groups, and compositional heterogeneity. All these findings were explained, as appropriate, considering the modeled active center distribution, MAO cage structure repeat units, proposed catalyst surface chemistry, segregation effects and the literature that concerns and supports this study. While doing so, new insights were obtained. Additionally, future research, along the direction

ANIONIC POLYMERIZATION OF ALKYL METHACRYLATES INITIATED BY nBuCu(NCy2)Li

Institute of Scientific and Technical Information of China (English)

Bing-yong Han; Jian-guo Liang; Jian-min Lu; Feng An; Wan-tai Yang

2009-01-01

Anionic polymerization of methyl methacrylate (MMA), n-butyl methacrylate (nBMA) and glycidyl methacrylate (GMA) initiated by nBuCu(NCy2)Li (1) in tetrahydrofuran (THF) at -50℃ to -10℃ was investigated. It was found that the polymerization of MMA and nBMA initiated by 1 proceeded quantitatively in THF to afford PMMA and PBMA with polydispersity index 1.15-1.30 and nearly 100% initiator efficiencies at -10℃. The molecular weights increased linearly with the ratio of [monomer]/[1]. However, a post-polymerization experiment carried out on this system revealed a double polymer peak by GPC when fresh monomer was added after an interval of 10 rain. Polymerization of styrene could be initiated by 1, but the initiator efficiency was low.

Water-n-BuOH solvothermal synthesis of ZnAl-LDHs with different morphologies and its calcined product in efficient dyes removal.

Science.gov (United States)

Huang, Gailing; Sun, Yingying; Zhao, Chencong; Zhao, Yifei; Song, Zhaoyuan; Chen, Junli; Ma, Shulan; Du, Junping; Yin, Zhigang

2017-05-15

In this study, water-n-BuOH mixed solvents were used to synthesize the ZnAl-layered double hydroxides (ZnAl-LDHs) via hydrothermal method. The XRD, FT-IR, SEM, ICP and CHN analyses revealed that the type of intercalated anions, the layer Zn/Al ratios, and morphologies of the LDHs depended on the ratio of V(water)/V(n-BuOH) in the mixed solvents. When the ratio of V(water)/V(n-BuOH) is 3 or 0.3, the as-prepared LDHs had 3D "silk flowers" (ZnAl-LDH-3) or "Sedimentary rock" morphology (ZnAl-LDH-0.3). Adsorption properties of dyes on calcined LDHs were studied. Compared with ZnAl-LDO-0.3 and ZnAl-LDO-w (calcined from the LDHs obtained in pure water), ZnAl-LDO-3 showed much better adsorption efficiency for anionic dyes thanks to its much larger BET-specific surface area. The sorption kinetics for dyes was appropriately described by the pseudo-second-order model and sorption isotherms can be fitted more satisfactorily by the Langmuir model. With the increasing concentrations of dyes from 10mg/L to 400mg/L, the maximum absorption capacities of ZnAl-LDO-3 were 1540mg/g (2.21mmol/g) for congo red, 1153mg/g (3.52mmol/g) for methyl orange and 390mg/g (0.63mmol/g) for active red (X-3B), respectively. The adsorption dyes onto the external surface is still the main mechanism for LDO adsorbents. The ZnAl-LDO-3 was a potential adsorbent for dyeing wastewater treatment. Copyright © 2017 Elsevier Inc. All rights reserved.

The titanium tris-anilide cation [Ti(N[(t)Bu]Ar)3](+) stabilized as its perfluoro-tetra-phenylborate salt: structural characterization and synthesis in connection with redox activity of 4,4'-bipyridine dititanium complexes.

Science.gov (United States)

Spinney, Heather A; Clough, Christopher R; Cummins, Christopher C

2015-04-21

This work explores the reduction of 4,4'-bipyridine using two equivalents of the titanium(iii) complex Ti(N[(t)Bu]Ar)3 resulting in formation of a black, crystalline complex, (4,4'-bipy){Ti(N[(t)Bu]Ar)3}2, for which an X-ray structure determination is reported. The neutral, black, 4,4'-bipyridine-bridged bimetallic was found to be redox active, with mono- and di-anions being accessible electrochemically, and with the mono- and di-cations also being accessible chemically, and isolable, at least when using the weakly coordinating anion [B(C6F5)4](-) as the counter-ion. It proved possible to crystallize the salt [(4,4'-bipy){Ti(N[(t)Bu]Ar)3}2][B(C6F5)4]2 for a single-crystal X-ray structure investigation; in this instance it was revealed that the aromaticity of the 4,4'-bipyridine ligand, that had been disrupted upon reduction, had been regained. A rare cationic d(0) metal tris-amide complex, shown by X-ray crystallography to contain an intriguing pyramidal TiN3 core geometry, namely {Ti(N[(t)Bu]Ar)3}(+), could also be isolated when using [B(C6F5)4] as the essentially non-interacting counter-ion. This highly reactive cation should be considered as a potential intermediate in the plethora of reactions wherein Ti(N[(t)Bu]Ar)3 has been shown to effect the reduction of substrates including halogenated organic molecules, carbonyl compounds, organic nitriles, and metal complexes.

Cadmium toxicity in Maize (Zea mays L.): consequences on antioxidative systems, reactive oxygen species and cadmium accumulation.

Science.gov (United States)

Anjum, Shakeel Ahmad; Tanveer, Mohsin; Hussain, Saddam; Bao, Mingchen; Wang, Longchang; Khan, Imran; Ullah, Ehsan; Tung, Shahbaz Atta; Samad, Rana Abdul; Shahzad, Babar

2015-11-01

Increased cadmium (Cd) accumulation in soils has led to tremendous environmental problems, with pronounced effects on agricultural productivity. Present study investigated the effects of Cd stress imposed at various concentrations (0, 75, 150, 225, 300, 375 μM) on antioxidant activities, reactive oxygen species (ROS), Cd accumulation, and productivity of two maize (Zea mays L.) cultivars viz., Run Nong 35 and Wan Dan 13. Considerable variations in Cd accumulation and in behavior of antioxidants and ROS were observed under Cd stress in both maize cultivars, and such variations governed by Cd were concentration dependent. Exposure of plant to Cd stress considerably increased Cd concentration in all plant parts particularly in roots. Wan Dan 13 accumulated relatively higher Cd in root, stem, and leaves than Run Nong 35; however, in seeds, Run Nong 35 recorded higher Cd accumulation. All the Cd toxicity levels starting from 75 μM enhanced H2O2 and MDA concentrations and triggered electrolyte leakage in leaves of both cultivars, and such an increment was more in Run Nong 35. The ROS were scavenged by the enhanced activities of superoxide dismutase, peroxidase, catalase, ascorbate peroxidase, and glutathione peroxidase in response to Cd stress, and these antioxidant activities were higher in Wan Dan 13 compared with Run Nong 35 at all Cd toxicity levels. The grain yield of maize was considerably reduced particularly for Run Nong 35 under different Cd toxicity levels as compared with control. The Wan Dan 13 was better able to alleviate Cd-induced oxidative damage which was attributed to more Cd accumulation in roots and higher antioxidant activities in this cultivar, suggesting that manipulation of these antioxidants and enhancing Cd accumulation in roots may lead to improvement in Cd stress tolerance.

Structure-activity relationship of linear peptide Bu-His-DPhe-Arg-Trp-Gly-NH(2) at the human melanocortin-1 and -4 receptors: histidine substitution.

Science.gov (United States)

Cheung, Adrian Wai-Hing; Danho, Waleed; Swistok, Joseph; Qi, Lida; Kurylko, Grazyna; Rowan, Karen; Yeon, Mitch; Franco, Lucia; Chu, Xin-Jie; Chen, Li; Yagaloff, Keith

2003-01-06

Systematic substitution of His(6) residue using non-selective hMC4R pentapeptide agonist (Bu-His(6)-DPhe(7)-Arg(8)-Trp(9)-Gly(10)-NH(2)) as the template led to the identification of Bu-Atc(6)(2-aminotetraline-2-carboxylic acid)-DPhe(7)-Arg(8)-Trp(9)-Gly(10)-NH(2) which showed moderate selectivity towards hMC4R over hMC1R. Further SAR studies resulted in the discovery of Penta-5-BrAtc(6)-DPhe(7)-Arg(8)-Trp(9)-Gly(10)-NH(2) and Penta-5-Me(2)NAtc(6)-DPhe(7)-Arg(8)-Trp(9)-Gly(10)-NH(2) which are potent hMC4R agonists and are inactive in hMC1R, hMC3R and hMC5R agonist assays.

Crystal Structure of Faradaurate-279: Au279(SPh-tBu)84 Plasmonic Nanocrystal Molecules.

Science.gov (United States)

Sakthivel, Naga Arjun; Theivendran, Shevanuja; Ganeshraj, Vigneshraja; Oliver, Allen G; Dass, Amala

2017-11-01

We report the discovery of an unprecedentedly large, 2.2 nm diameter, thiolate protected gold nanocrystal characterized by single crystal X-ray crystallography (sc-XRD), Au 279 (SPh-tBu) 84 named Faradaurate-279 (F-279) in honor of Michael Faraday's (1857) pioneering work on nanoparticles. F-279 nanocrystal has a core-shell structure containing a truncated octahedral core with bulk face-centered cubic-like arrangement, yet a nanomolecule with a precise number of metal atoms and thiolate ligands. The Au 279 S 84 geometry was established from a low-temperature 120 K sc-XRD study at 0.90 Å resolution. The atom counts in core-shell structure of Au 279 follows the mathematical formula for magic number shells: Au@Au 12 @Au 42 @Au 92 @Au 54 , which is further protected by a final shell of Au 48 . Au 249 core is protected by three types of staple motifs, namely: 30 bridging, 18 monomeric, and 6 dimeric staple motifs. Despite the presence of such diverse staple motifs, Au 279 S 84 structure has a chiral pseudo-D 3 symmetry. The core-shell structure can be viewed as nested, concentric polyhedra, containing a total of five forms of Archimedean solids. A comparison between the Au 279 and Au 309 cuboctahedral superatom model in shell-wise growth is illustrated. F-279 can be synthesized and isolated in high purity in milligram quantities using size exclusion chromatography, as evidenced by mass spectrometry. Electrospray ionization-mass spectrometry independently verifies the X-ray diffraction study based heavy atoms formula, Au 279 S 84 , and establishes the molecular formula with the complete ligands, namely, Au 279 (SPh-tBu) 84 . It is also the smallest gold nanocrystal to exhibit metallic behavior, with a surface plasmon resonance band around 510 nm.

Early age hydration of calcium sulfoaluminate (synthetic ye'elimite, ) in the presence of gypsum and varying amounts of calcium hydroxide

KAUST Repository

Hargis, Craig W.; Kirchheim, Ana Paula; Monteiro, Paulo J.M.; Gartner, Ellis M.

2013-01-01

Suspensions of synthetic ye'elimite (C4A3S̄) in a saturated gypsum (CS̄H2) and calcium hydroxide (CH) solution were examined in-situ in a wet cell by soft X-ray transmission microscopy and ex-situ by scanning electron microscopy. The most voluminous hydration product observed was ettringite. Ettringite commonly displayed acicular, filiform, reticulated, and stellate crystal habits. Additionally, pastes with C 4A3S̄, 15% CS̄H2, and varying amounts of CH were prepared and examined with X-ray diffraction (XRD) and isothermal calorimetry. The XRD experiments showed that increasing CH content caused more solid solution (SO4 2 -/OH-) AFm phases to form at early ages (< 1 d) and more monosulfate to form at later ages (> 1 d). Calorimetry indicated that the increased production of solid solution AFm was accompanied with an increase in the initial (< 30 min) rate of heat evolution, and increasing CH generally reduced the time till the second maximum rate of heat evolution due to the formation of ettringite and monosulfate. © 2013 Elsevier Ltd.

Early age hydration of calcium sulfoaluminate (synthetic ye'elimite, ) in the presence of gypsum and varying amounts of calcium hydroxide

KAUST Repository

Hargis, Craig W.

2013-06-01

Suspensions of synthetic ye\\'elimite (C4A3S̄) in a saturated gypsum (CS̄H2) and calcium hydroxide (CH) solution were examined in-situ in a wet cell by soft X-ray transmission microscopy and ex-situ by scanning electron microscopy. The most voluminous hydration product observed was ettringite. Ettringite commonly displayed acicular, filiform, reticulated, and stellate crystal habits. Additionally, pastes with C 4A3S̄, 15% CS̄H2, and varying amounts of CH were prepared and examined with X-ray diffraction (XRD) and isothermal calorimetry. The XRD experiments showed that increasing CH content caused more solid solution (SO4 2 -/OH-) AFm phases to form at early ages (< 1 d) and more monosulfate to form at later ages (> 1 d). Calorimetry indicated that the increased production of solid solution AFm was accompanied with an increase in the initial (< 30 min) rate of heat evolution, and increasing CH generally reduced the time till the second maximum rate of heat evolution due to the formation of ettringite and monosulfate. © 2013 Elsevier Ltd.

Nález zbytků pozdně renesančních kachlových kamen na hradě Buštěhrad

Czech Academy of Sciences Publication Activity Database

Durdík, Tomáš; Juřina, P.; Pavlík, Č.

2010-01-01

Roč. 12, - (2010), s. 509-528 ISSN 1211-6831 Institutional research plan: CEZ:AV0Z80020508 Keywords : castle * castellology * Buštěhrad * stove tiles * postmedieval archaeology * material culture * Bohemia * renaissance Subject RIV: AC - Archeology, Anthropology, Ethnology

Blood pressure self-monitoring in pregnancy (BuMP) feasibility study; a qualitative analysis of women's experiences of self-monitoring.

Science.gov (United States)

Hinton, Lisa; Tucker, Katherine L; Greenfield, Sheila M; Hodgkinson, James A; Mackillop, Lucy; McCourt, Christine; Carver, Trisha; Crawford, Carole; Glogowska, Margaret; Locock, Louise; Selwood, Mary; Taylor, Kathryn S; McManus, Richard J

2017-12-19

Hypertensive disorders in pregnancy are a leading cause of maternal and fetal morbidity worldwide. Raised blood pressure (BP) affects 10% of pregnancies worldwide, of which almost half develop pre-eclampsia. The proportion of pregnant women who have risk factors for pre-eclampsia (such as pre-existing hypertension, obesity and advanced maternal age) is increasing. Pre-eclampsia can manifest itself before women experience symptoms and can develop between antenatal visits. Incentives to improve early detection of gestational hypertensive disorders are therefore strong and self-monitoring of blood pressure (SMBP) in pregnancy might be one means to achieve this, whilst improving women's involvement in antenatal care. The Blood Pressure Self-Monitoring in Pregnancy (BuMP) study aimed to evaluate the feasibility and acceptability of SMBP in pregnancy. To understand women's experiences of SMBP during pregnancy, we undertook a qualitative study embedded within the BuMP observational feasibility study. Women who were at higher risk of developing hypertension and/or pre-eclampsia were invited to take part in a study using SMBP and also invited to take part in an interview. Semi-structured interviews were conducted at the women's homes in Oxfordshire and Birmingham with women who were self-monitoring their BP as part of the BuMP feasibility study in 2014. Interviews were conducted by a qualitative researcher and transcribed verbatim. A framework approach was used for analysis. Fifteen women agreed to be interviewed. Respondents reported general willingness to engage with monitoring their own BP, feeling that it could reduce anxiety around their health during pregnancy, particularly if they had previous experience of raised BP or pre-eclampsia. They felt able to incorporate self-monitoring into their weekly routines, although this was harder post-partum. Self-monitoring of BP made them more aware of the risks of hypertension and pre-eclampsia in pregnancy. Feelings of

Quality control of the Korle Bu rectilinear scanner

International Nuclear Information System (INIS)

Feli, S.K.; Tetteh, G.K.

1993-01-01

The attainment of high standards of efficiency and reliability in the practice of nuclear medicine requires an appropriate quality assurance programme. Routine monitoring of nuclear medicine instruments, using test procedures that provide check of the quality and reproducibility of instrument performance, aims at giving the user the confidence in the data collected and in updating the performance of the instrument. Quality control testing schedule for rectilinear scanners include weekly density calibration and monthly performance contrast enhancement and collimator evaluation. Discussion in this work is restricted to collimator evaluation which is required to be performed at the initial stages of installation as acceptance reference. However unlike the density, calibration and contrast enhancement, there is no documented work on this for the M800 Scintikart Scanner - a Hungarian Gamma Muvek system belonging to the Korle Bu Hospital, Accra. Tests of linearity of energy, relative sensitivity and resolution including energy and spatial resolutions were conducted in respect of collimator evaluation. In the linearity test it was ascertained that a nonlinear relationship exists between the centre of the window setting and the energy of the photopeak. The spectrometer was calibrated independently for each radionuclide and the position of Tc-99m obtained at 0.45 MeV on the MeV scale. In addition, the F272a13 Collimator offered a better resolution than the routinely used F272a136 collimator which has the highest sensitivity. (author). 10 refs.; 1 tab.; 10 figs

Synthesis, characterization, and reactivity of nickel hydride complexes containing 2,6-C6H3(CH2PR2)2 (R = tBu, cHex, and iPr) pincer ligands.

Science.gov (United States)

Boro, Brian J; Duesler, Eileen N; Goldberg, Karen I; Kemp, Richard A

2009-06-15

The syntheses and full characterization of nickel hydrides containing the PCP "pincer"-type ligand, where PCP = 2,6-C(6)H(3)(CH(2)PR(2))(2) (R = tBu, cHex, and iPr), are reported. These Ni-H complexes are prepared by the conversion of ((R)PCP)NiCl precursors into the corresponding nickel hydrides by use of appropriate hydride donors. Surprisingly, although the ((R)PCP)NiCl precursors are quite similar chemically, the conversions to the hydrides were not straightforward and required different hydride reagents to provide analytically pure products. While NaBH(4) was effective in the preparation of pure ((tBu)PCP)NiH, Super-Hydride solution (LiEt(3)BH in THF) was required to prepare either ((cHex)PCP)NiH or ((iPr)PCP)NiH. Attempts to prepare a Ni-H from ((Ph)PCP)NiCl with a variety of hydride reagents yielded only the free ligand as an identifiable product. Two of the derivatives, tBu and cHex, have also been subjected to single crystal X-ray analysis. The solid-state structures each showed a classic, near-square planar arrangement for Ni in which the PCP ligand occupied three meridional ligand points with the Ni-H trans to the Ni-C bond. The resulting Ni-H bond lengths were 1.42(3) and 1.55(2) A for the tBu and cHex derivatives, respectively.

ELVİYE-İ SELASE/ÜÇ SANCAK (KARS, ARDAHAN VE BATUM)'DA ERMENİLERİN TÜRKLERE YAPTIKLARI MEZALİM

OpenAIRE

Dayı (Derinsu), Esin

2010-01-01

ÖZETRuslar, LDünya Savaşı'nda işgal ettikleri Anadolutopraklarından Erzincan Mütarekesi geregince geri çekilince;yerlerine işbirlikçi silahlı Ermeni çeteleri geçmiş, bu çeteler DoguAnadolu ve Elviye-i Sel4sç'de Türk katliamı .ve mezalimibaşlatmışlardı, .Bölgede Ermenilerin Türklere yaptıkları, insanlıgın asla kabuledemeyecegi vahşet ve katliama son vermek maksadıyl...

Care Management: Adherence to Therapies Among Patients at Bu-Alicina Clinic, Qazvin, Iran

Directory of Open Access Journals (Sweden)

S Asefzadeh

2005-11-01

Full Text Available Background: Non-adherence to treatment is a problem of increasing concern for all stakeholders. This study was designed to determine the prevalence of non-adherence among the clients consulting internists or cardiologists at Bu-Alicina Clinic in Qazvin. Methods: A total number of 400 clients came to Bu-Alicina Clinic (center for internal medicine and cardiology were randomly interviewed through a questionnaire during a two month period in 2003. Self-administered methods were used if the clients applied. The data were interpreted using statistical methods. Results: The clients were between 14 and 78 years old (33.7+8.5 and 57.5% of them were women and 42.5% were men. Of total number, 30.7% were consulting for continuation of their therapies and of these clients, 41.5% had pooradherence to their current therapies. The more educated clients were 1.6 times (OR=1.62; 95% CI=0.71, 3.74 likely to be more adherent to the therapies.There was no significant difference between the internal diseases patients and cardiology patients in this regard (41.7%vs 40%. Of the total number of 400 clients, 79.5% had history of consulting to medical clinics during the last three months and 37.4% of them had non-adherence to their past therapies. The more frequent factors were: forgetfulness (13.3%, not to be able to afford to pay for treatment costs (10.3%, disbelieve to the doctor and consulting another ones (8.4%, long distance (8.4%, feeling that it is not important to take medications (7.4%, side effects (7.4%, disbelieve to the diagnosis (7.1%, religious considerations (6.5%, and misunderstanding or lack of information about the prescription (5.8%. No significant difference was found between men and women on this aspect. Conclusion: Patients need advice, supported information from professionals about their health and therapies. Certain studies must be done to determine the pitfalls and effective interventions address that barriers can be developed. Keywords

Validation of the Samsung SBM-100A and Microlife BP 3BU1-5 wrist blood pressure measuring devices in adults according to the International Protocol.

Science.gov (United States)

Altunkan, Sekip; Ilman, Nevzat; Altunkan, Erkan

2007-04-01

A variety of automatic blood measurement devices with diverse features have been introduced to the medical markets recently. Among these devices, models that measure at the wrist have become increasingly popular in self measurements. The objective of this study was to evaluate the accuracy of the Samsung SBM-100A and Microlife BP 3BU1-5 wrist blood pressure devices against the mercury sphygmomanometer in adults according to the International Protocol criteria. Fifty-four patients over 30 years of age were studied and classified based on the International Protocol range. Blood pressure measurements at the wrist with the Samsung SBM-100A and Microlife BP 3BU1-5 were compared with the results obtained by two trained observers using a mercury sphygmomanometer. Nine sequential blood pressure measurements were taken. A total of 33 participants with randomly distributed arm circumferences were selected for both of the validation studies. During each validation study, 99 measurements were obtained for comparison from 33 participants. The first phase was performed on 15 participants and if the device passed this phase, 18 more participants were selected. Mean discrepancies and standard deviations of the device-sphygmomanometer were 0.9+/-9.2 and -2.7+/-9.3 mmHg for systolic blood pressure and -1.4+/-8.0 mmHg and 1.4+/-5.7 for diastolic blood pressure in the Samsung and Microlife study groups, respectively. The Samsung SBM-100A passed Phase 1 in 15 participants. Despite the fact that Microlife BP 3BU1-5 passed Phase 1 for diastolic pressure, it failed according to the systolic pressure criteria. Eighteen patients were added and Phase 2 was continued, in which Samsung SBM-100A failed to meet the criteria of Phases 2.1 and 2.2 for adults in systolic and diastolic blood pressure. It was found that the Microlife BP 3BU1-5 does not meet the criteria of either of Phases 2.1 and 2.2 for systolic blood pressure and Phase 2.2 for diastolic blood pressure. In this study, Samsung SBM

Henequén'ın Dönüşü, Bir Yeşil Lif İle Yucatan'da Karmaşık Bir Tarih

OpenAIRE

ANAYA, Yosi

2014-01-01

Meksika Mayaları ve Orta Amerika'nın önde gelen liflerinden birisi, sisal olarak bilinen Henequéndir. Sömürgecilik döneminin üretim merkezlerinden birisi olan Yucatan'ınadını alan Henequén, yüzyıllarca Yucatan Yarımadasının “Yeşil Altın”ı olarak bilindi. Yucatek ekonomisi, 20. yüzyıl boyunca ihtiyaç duyulan her türlü ip, halı,çuval ve kaba kumaşları sağlayan henequén tarlaları etrafında gelişti, yerleşti ve serpildi. 20. yüzyılda henequén lifi, daha ucuz fiyatlarla Madagaskar ve Ken...

Los Rinoceróntidos fósiles del Mioceno inferior de Buñel (Valencia

Directory of Open Access Journals (Sweden)

Belinchón, M.

1984-04-01

Full Text Available We have studied the fossil Rhinocerotidae from Buñol (Valencia, Spain. It is realized as stratigraphic synthesis of the deposit and dated as Orleanium Mammal Age (lower-middle Aragonium, which is equivalent to the 4b Neogene MammaL Unit (zonation of Mein, 1976. We conclude that the fossil association is a thanatocoenosis, with strongly rounded elements. The paleoenvironment, in which this association was accumulated, was a marsh zone in the distal part of an alluvial fan. Two species of Rhinocerotidae have been determined, one of the ,genus Acerotherium and another of the genus Dicerorhinus. The second is more abundant than the former and probably it would be adapted to a marshy habitat. We describe and figure the more representative material of both species.

Se han estudiado los Rinoceróntidos fósiles de Buñol (Valencia. Se realiza una síntesis estratigráfica del yacimiento, estableciéndose su edad orleaniense (Aragoniense inferior-medio, equivalente a la zona 4b de la zonación de Mein (1975. Se concluye que el yacimiento corresponde a una tanatocenosis, con elementos fuertemente rodados, acumulada en una zona palustre situada en la parte distal de un abanico aluvial. Se han determinado dos especies de Rinoceróntidos: una, correspondiente al género Aceratherium, está poco representada y otra, asignable al género Dicerorhinus, es más abundante y probablemente estaba adaptada a un hábitat pantanoso. Se describe y figura el material más representativo de ambas especies.

İNOVASYON VE İNOVASYON GÖSTERGELERİ: AB ÜLKELERİ VE TÜRKİYE KARŞILAŞTIRMASI

OpenAIRE

ŞAHİNLİ, Mehmet Arif; KILINÇ, Efecan

2013-01-01

Literatürde inovasyonu ölçen ve ülkelerin inovasyon performanslarını ortaya koyan birçok gösterge bulunmaktadır. Bilgi yoğun sektörlerdeki istihdam, Toplam Faktör Verimliliği (TFV), AR&GE harcamaları, patent başvuru ve tescil sayıları, girişimci, araştırmacı ve teknisyen sayıları, ileri teknoloji ihracatı, royalti ve lisans ücretleri, endüstri katma değeri, inovasyon kapasitesi ile Bilgi ve İletişim Teknolojileri (BİT)’nin ihracatı bu göstergelerden bazılarıdır. İnovasyonun en önemli ...

Datorprogrammas kā autortiesību aizsardzības objekti Latvijas Republikā

OpenAIRE

Cers, Gatis

2008-01-01

Bakalaura darbā autors analizē datorprogrammu aizsardzību ar autortiesībām Latvijas Republikā. Tiek aplūkota datorprogrammas legālās definīcijas nepieciešamība, kā arī datorprogrammu autoru iespējas aizsargāt savas tiesības gan vēršoties tiesā, gan ārpus tās. Autors Latvijas Republikas tiesisko regulējumu salīdzina ar citās valstīs pastāvošajiem regulējumiem un sniedz priekšlikumus Latvijas Republikā spēkā esošo normatīvo aktu piemērošanā, kā arī piedāvā veikt labojumus atsevišķos normatīvajo...

Practical Stannylation of Allyl Acetates Catalyzed by Nickel with Bu3 SnOMe.

Science.gov (United States)

Komeyama, Kimihiro; Itai, Yuuhei; Takaki, Ken

2016-06-27

A practical and scalable nickel-catalyzed allylic stannylation of allyl acetates with Bu3 SnOMe is described. A variety of acyclic and cyclic allyl acetates, even with base-sensitive moieties, undergoes the stannylation by using NiBr2 /4,4'-di-tert-butylbipyridine (dtbpy)/Mn catalyst system to afford highly functionalized allyl stannanes with excellent regioselectivity and yields. Furthermore, the scope of protocol is also extended by the reaction of propargyl acetates, giving rise to propargyl or allenyl stannanes. Additionally, a unique diastereoselectivity using the nickel catalyst different from the palladium was demonstrated for the stannylation of cyclic allyl acetates. In the reaction, inexpensive and stable nickel complexes, abundant reductant (Mn), and atom-economical stannyl source were used. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Internacjonalizmy jako źródło ekwonimii w słowiańskiej terminologii technicznej (na materiale polskim, rosyjskim i bułgarskim

Directory of Open Access Journals (Sweden)

Julia Mazurkiewicz-Sułkowska

2015-12-01

Full Text Available Internationalisms as a source of equonymy in Slavic technical terminology (on the basis of Polish, Russian and Bulgarian material The article presents one of the main sources of Slavic synonymy in technical terms – the phenomenon of internationalization. On the basis of a compre­hensive set of Polish, Russian and Bulgarian terms of the range of machinery (construction and operation it was found that Polish terminology uses international units primarily as a component of analytic terms, while the Russian and Bulgarian usually borrow the entire terminological unit and less often use a parallel native term.   Internacjonalizmy jako źródło ekwonimii w słowiańskiej terminologii technicznej (na materiale polskim, rosyjskim i bułgarskim W artykule przedstawiono jedno z głównych źródeł ekwonimii w słowiańskiej terminologii technicznej – zjawisko internacjonalizacji. Na podstawie analizy obszernego zbioru polskich, rosyjskich i bułgarskich terminów z zakresu budowy i eksploatacji maszyn ustalono, że polska terminologia używa jedno­stek międzynarodowych przede wszystkim jako części składowej terminów analitycznych, zaś rosyjski i bułgarski systemy terminologiczne zapożyczają zazwyczaj całą jednostkę terminologiczną i rzadziej używają równolegle ter­minu rodzimego.

Veiksmīgu biznesa attiecību veidošana ar Japānu: lietišķā etiķete.

OpenAIRE

Korde, Roberts

2014-01-01

Bakalaura darbs veltīts Japānas lietišķās etiķetes nozīmīguma izpētei starptautisku biznesa attiecību ietvaros. Japānas kultūra arī mūsdienās ir spējusi saglabāt savas tradicionālās iezīmes. Japāņi pievērš uzmanību detaļām un pareizai rīcībai, tāpēc lietišķā etiķete ieņem būtisku lomu Japānas biznesa vidē. Šī darba mērķis ir noskaidrot, cik nozīmīga mūsdienās ir Japānas lietišķā etiķete starptautiskās biznesa attiecībās. Tādēļ darbā tiks apskatīti cēloņi, kāpēc Japānas lietišķā etiķete...

Piesaistes stila saistība ar apmierinātību ar dzīvi

OpenAIRE

Čiekure, Līva

2015-01-01

Pētījuma mērķis ir noskaidrot vai pastāv saistības starp piesaistes stilu un apmierinātību ar dzīvi. Tika aptaujāti 100 respondenti- 50 sievietes un 50 vīrieši. Pētījumā tika izmantotas Piesaistes stilu aptauja (Attachment Styles -Inventory /ASI/, Sperling & Berman, 1991), Latvijā adaptējusi Baiba Martinsone (2003) un Apmierinātības ar dzīvi aptauja ( Satisfaction with life scales,/SWLS/, Diener, 1985), Latvijā adaptēja Maslovska, Voitkāne, Miezīte & Raščevska ( 2005) un Upmane (Upmane, 2010)...

Liselerde Okutulmakta Olan Lise I. Sınıf Matematik Kitaplarının Değerlendirilmesi

OpenAIRE

ŞAHIN, Sevgi; TURANLI, Necla

2014-01-01

Bu çalışma lise I. sınıflardaki matematik derslerinde okutulan ders kitaplarının ve yardımcı kitapların öğrenmeyi sağlamadaki ve ÖSS\\'ye katkıları yönünden öğretmen ve öğrenci görüşlerini belirlemek amacıyla hazırlanmıştır. İstanbul ili dahilinde, Çağaloğlu Anadolu Lisesi, Bahçelievler Anadolu Lisesi, Adnan Menderes Anadolu Lisesi, Özel Safiye Sultan Kız Lisesi, Ataköy Cumhuriyet Lisesi, Pertevniyal Anadolu Lisesi, Özel Arel Koleji, Ataköy Lisesi ve Bahçelievler Lisesi\\'nde görev y...

Polymerization of MMA catalyzed by different novel mixed ligand lanthanocene ｛ ( Cp ) ( Cl ) LnSchiff-base (THF) ｝, ( COT ) Ln(methoxyethylindenyl) (THF)/Al (i-Bu) 3 systems

Institute of Scientific and Technical Information of China (English)

YOUSAF, Muhammad; QIAN, Yan-Long; FENG, Zuo-Feng; HUANG, Ji-Ling; SUN, Jun-Quan; PAN, Zhi-Da

2000-01-01

This article deals that the rare earth metal complexes along with Al (i-Bu)3 can catalyze the polymerization of methyl methacrylate (MMA) into high molecular weight poly(MMA) along with narrow molecular weight distributions (MWD). A typical example wan mentioned in the case of ｛Cp(Cl)Sm Schiff-base(THF)｝ which expresses maximum (conv.%= 55.46 and Mn=354×103) efficiency along with narrow MWD(Mw/Mn＜2) at 60°C. The resulting polymer was partially syndiotactic (＞60%). The effect of the catalyst, temperature, catalyst/MMA molar ratio, catalyst/Al(i-Bu)3 molar ratio on the polymerization of MMA at 60°C were also investigated.

Synthesis of Aromatic Thiolate-Protected Gold Nanomolecules by Core Conversion: The Case of Au36(SPh-tBu)24.

Science.gov (United States)

Theivendran, Shevanuja; Dass, Amala

2017-08-01

Ultrasmall nanomolecules (<2 nm) such as Au 25 (SCH 2 CH 2 Ph) 18 , Au 38 (SCH 2 CH 2 Ph) 24 , and Au 144 (SCH 2 CH 2 Ph) 60 are well studied and can be prepared using established synthetic procedures. No such synthetic protocols that result in high yield products from commercially available starting materials exist for Au 36 (SPh-X) 24 . Here, we report a synthetic procedure for the large-scale synthesis of highly stable Au 36 (SPh-X) 24 with a yield of ∼42%. Au 36 (SPh-X) 24 was conveniently synthesized by using tert-butylbenzenethiol (HSPh-tBu, TBBT) as the ligand, giving a more stable product with better shelf life and higher yield than previously reported for making Au 36 (SPh) 24 from thiophenol (PhSH). The choice of thiol, solvent, and reaction conditions were modified for the optimization of the synthetic procedure. The purposes of this work are to (1) optimize the existing procedure to obtain stable product with better yield, (2) develop a scalable synthetic procedure, (3) demonstrate the superior stability of Au 36 (SPh-tBu) 24 when compared to Au 36 (SPh) 24 , and (4) demonstrate the reproducibility and robustness of the optimized synthetic procedure.

15. YÜZYIL ŞAİRLERİNDEN DİYARBAKIRLI HALÎLÎ’NİN ŞİİRLERİ / THE POEMS OF HALÎLÎ WHO IS A 15th CENTURY POET FROM DIYARBAKIR

Directory of Open Access Journals (Sweden)

Ahmet KAVAKLIYAZI

2015-12-01

Full Text Available Klasik Türk edebiyatında divanı bugün için elimizde bulunmayan kimi şairlerin şiirleri, şiir mecmualarında karşımıza çıkmaktadır. Bu şairlerden biri de Firkat-nâme’si ile tanınan, 15. yüzyıl şairi Diyarbakırlı Halîlî’dir.Halîlî’nin belli başlı mecmualardaki şiirleri daha önce bazı akademik çalışmalara konu edilmişti. Üzerine yüksek lisans tezi hazırladığımız Koyunoğlu Müzesi Kütüphanesinde bulunan 13450 numaralı mecmuada Halîlî’nin, önceki yayımlarda bulunmayan şiirlerinin olduğunu gördük. Ayrıca, mecmualarda Halîlî’ye ait bazı şiirlerin onun Firkat-nâme’sinde geçen şiirler olması sebebiyle bu eserdeki şiirlerin ayrılması ve mecmuaların yeniden taranarak diğer şiirlerinin belirlenmesi gerekmekteydi.Çalışmamızda Halîlî’nin Firkat-nâme dışındaki şiirleri mecmualar taranarak tespit edilmiş, bu şiirlerin ona aidiyeti saptanmış ve şiirlerin karşılaştırmalı metni verilmiştir.

Filme kaladest : "Maelströmi" külm langemine, "Bo Ba Bu" kiviaegne röhkimine ja vanameister Imamura "Soe vesi punase silla all" / Erkki Luuk

Index Scriptorium Estoniae

Luuk, Erkki, 1971-

2001-01-01

Temaatiliselt koos vaadeldakse kolme erineva kultuuritaustaga režissööri filme : kanadalase Denis Villeneuve "Maelström", usbeki Ali Hamrajevi "Bo Ba Bu" ja jaapanlase Shohei Imamura "Soe vesi punase silla all"

Patient dose assessment from fluoroscopic procedures at Korle-Bu Teaching Hospital

International Nuclear Information System (INIS)

Gyekye, P. K.

2008-06-01

Organ and effective dose to ninety (90) patients undergoing myelogram, urethrogram, barium swallow, barium meal and barium enema examinations at the KorIe-Bu Teaching Hospital was estimated using the Monte Carlo Code (PCXMC). Free in air measurements were made with a calibrated ionisation chamber to estimate the entrance surface air kerma for each examination. Evaluation of fluoroscopy beam on time and number of radiographs taken per patient was done for all the examinations considered and studies were done on how they affect patient dose. Dose area product (DAP) was calculated from the entrance surface air kerma and the area of the beam on the surface of the patient and compared with internationally accepted reference levels. Excess relative risk of site specific solid cancer and all solid cancers excluding thyroid and Non-melanoma skin cancers incidences were estimated for the various examinations using Biological Effects of Ionising Radiation VII Committee risk model from the knowledge of the mean effective doses for each examination. The mean effective dose was found to be 0.29 :±: 0.07 mSv for urethrogram, 0.84:±: 0.13 mSv for barium swallow, 3.15 :±: 0.44 mSv for barium meal, 6.24 :±: 0.7 mSv for barium enema and 0.38 :I: 0.05 mSv for myelogram examinations. The estimated mean dose area product (DAP) was found to be 3.55 :±: 0.95 Gycm2 for urethrogram, 16.44:1: 2.60 Gycm2 for barium swallow, 50.81 :±: 7.04 Gycm2 for barium meal, 99.69 :±: 10.85 Gycm2 for barium enema and 9.32 :±: 0.99 Gycm2 for myelogram examinations. The estimated excess relative risk for the occurrence of all solid cancer was found to be 9.5700E-S and 1.6530E-4 for males and females respectively undergoing urethrogram examination, 2.7720E-4 and 4.7880E-4 for males and females respectively undergoing barium swallow examination, 1.0395E-3 and 1.7955E-3 for males and females respectively undergoing barium meal examination, 2.0592E-3 and 3.5568E-3 for males and females respectively

Soya ve Buğday Rüşeymi Katkılı Unların Kalitesini Düzeltme İmkanları Üzerinde Araştırmalar

Directory of Open Access Journals (Sweden)

Berrin Kahveci

2015-02-01

Full Text Available Araştırmada üç ayrı kalitedeki una, ısıl işlem uygulanmış muhtelif oranlarda tam yağlı ve yağsız soya veya tam yağlı ve yağsız buğday rüşeymi katılarak bunların ekmeklik kalitesine etkileri araştırılmıştır. Sonra soya veya buğday rüşeymi katkılı örneklere %0.2 ve %0.4 oranında SSL katılarak bunun ekmek özelliklerini düzeltici etkileri tespit edilmiştir. Soya ve rüşeym katkıları ekmeklerde hacim verimini ve Dallmann değerini düşürmüş, gözenek yapısını olumsuz yönde etkilemiştir. Genelde soyanın ekmek kalitesine olumsuz etkileri, buğday rüşeymine kıyasla daha az olmuştur. SSL katkısı örneklerin ekmeklik özelliklerini önemli ölçüde iyileştirmiştir.

KO t Bu-Initiated Aryl C–H Iodination: A Powerful Tool for the Synthesis of High Electron Affinity Compounds

KAUST Repository

Shi, Qinqin

2016-03-21

An efficient iodination reaction of electron-deficient heterocycles is described. The reaction utilizes KOtBu as an initiator and likely proceeds by a radical anion propagation mechanism. This new methodology is particularly effective for functionalization of building blocks for electron transport materials. Its utility is demonstrated with the synthesis of a new perylenediimide-thiazole non-fullerene acceptor capable of delivering a power conversion efficiency of 4.5% in a bulk-heterojunction organic solar cell. © 2016 American Chemical Society.

Checklist of the soil and moss testate amoebae (Protozoa, Rhizopoda) from the National Nature Reserve Voděradské bučiny (Czech Republic)

Czech Academy of Sciences Publication Activity Database

Balík, Vladimír

2001-01-01

Roč. 170, 1-4 (2001), s. 91-104 ISSN 0139-9543 R&D Projects: GA AV ČR IAA6066702 Institutional research plan: CEZ:AV0Z6066911 Keywords : Testacea * faunistic * Voděradské bučiny National Nature Reserve Subject RIV: EH - Ecology, Behaviour

ELVİYE-İ SELASE/ÜÇ SANCAK (KARS, ARDAHAN VE BATUM)'DA ERMENİLERİN TÜRKLERE YAPTIKLARI MEZALİM

OpenAIRE

Dayı (Derinsu), Esin

2010-01-01

ÖZETRuslar, LDünya Savaşı'nda işgal ettikleri Anadolutopraklarından Erzincan Mütarekesi geregince geri çekilince;yerlerine işbirlikçi silahlı Ermeni çeteleri geçmiş, bu çeteler DoguAnadolu ve Elviye-i Sel4sç'de Türk katliamı .ve mezalimibaşlatmışlardı, .Bölgede Ermenilerin Türklere yaptıkları, insanlıgın asla kabuledemeyecegi vahşet ve katliama son vermek maksadıyla TürkOrdusu 12 Şubat 1915'de başlatlıgı ileri bir ha...

Quantitative Analysis of Bone Scintigrams at the Korle-Bu Teaching Hospital

International Nuclear Information System (INIS)

Huguette, E.Y.Y.

2012-01-01

Qualitative method of diagnosis has been the traditional means of diagnosing bone tumours at the Nuclear Medicine Department of the Korle-Bu Teaching Hospital over the years. Although this method is commendable, a more accurate diagnostic means is the quantitative approach. Study on ninety-five patients undergoing bone scans has been performed quantitatively using image J. The patients were administered with activity ranging from 15 to 30 mCi depending on their weights, and were then scanned with an installed e.Cam SPECT system. A 256 x 1024 matrix size was used in acquiring the bone scans. Quantitative analyses performed with the image J, revealed that uptake levels in all selected body parts were higher for metastatic tumours compared to non-metastatic tumours. The average normalised uptake in the recorded metastatic cases was 1.37332 cts/mm 2 /mCi and the corresponding uptake in the non-metastatic cases was 0.85230 cts/mm 2 /mCi. The relative higher uptake in metastatic tumours is attributed to high osteoblastic activity and blood flow in metastatic cases compared to non-metastatic cases. Quantitative assessment of bone scintigrams is recommended for its high accuracy and quicker means of diagnosing.(author)

Ergenlik Dönemi Okuma Tutumu Ölçeği’nin Türkçe’ye Uyarlanması The Adaptasyon Of Survey Of Adolescent Reading Attitudes (Sara Into Turkish

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Muhammet BAŞTUĞ

2013-07-01

Full Text Available The aim of this study is to adapt the Survey of Adolescent Reading Attitudes SARA to Turkish, which was developed by McKenna, Conradi, Lawrance, Jang, and Meyer (2012, and to test it for validity and reliability. The rationale is that the scale involves one’s attitude towards digital reading. The sample was comprised of 702 sixth,seventh and eighth grade students in Konya- 343 of them being femaleand the remaining 359 being male. The original scale had 18 items infour sub-dimensions, namely academic reading in digital settings (AD,recreational reading in digital settings (RD, academic reading in printsettings (AP and recreational reading in print settings (RP. Theexploratory factor analysis and confirmatory factor analysis revealedthat the four original sub-dimensions were retained when two itemswere omitted. Cronbach’s alpha coefficients were 0.691, 0.802, 0.690,0.660 and 0.623 for the overall scale, RD, RP, AP and AD respectively.The results suggest that the adapted scale is reliable and valid. The 15-item finalized version is appropriate for the Turkish language and use inTurkey. In the development of reading environments and materials,identification of students’ attitudes toward reading in a multidimensionalway is expected to make great contributions to morequalified learning environments. Bu araştırmanın amacı, McKenna, Conradi, Lawrence, Jang ve Meyer (2012 tarafından geliştirilen Ergenlik Dönemi Okuma Tutumu Ölçeği’nin geçerlik ve güvenirliğinin yapılarak Türkçe’ye uyarlanmasıdır. Ölçeğin dijital okumaya karşı tutumu da kapsaması sebebiyle uyarlama çalışmasının uygun olacağı düşünülmüştür. Çalışma grubunu Konya ilinde yer alan ve 6,7 ve 8. Sınıflara devam eden 343’ü kız, 359’u erkek toplam 702 öğrenci oluşturmuştur. Ölçeğin orjinali 18 maddeden ve “Akademik Dijital, Serbest Dijital, Akademik Kağıt ve Serbest Kağıt” olmak üzere 4 alt boyuttan olu

Symptoms and sources of Yersinia enterocolitica-infection: a case-control study

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Siitonen Anja

2010-05-01

Full Text Available Abstract Background Yersinia enterocolitica (YE is the causative agent of yersiniosis. YE encompass strains of diverse pathogenicity: YE biotypes 1B and 2-5 are considered pathogenic, whereas biotype 1A is in general considered nonvirulent. Also YE-like species, which can sometimes be misidentified as YE, are considered nonvirulent. Methods In order to study differences in clinical picture caused by different YE types and their possible sources a case-control study was conducted in 2006. In this case-control study, 295 case-patients with YE or YE-like finding and their 758 controls responded to the questionnaire about symptoms and possible sources of infection. Results Strains of pathogenic YE bio/serotypes 3-4/O:3 or 2/O:9 were found in 18%, YE biotype 1A in 65% and YE -like strains of 17% of the patients. Patients infected with the strains of pathogenic YE bio/serotypes were younger and had fever more often than those with BT 1A who suffered more from vomiting. Symptoms of reactive arthritis were reported by 10% of pathogenic YE infections, 3% of YE BT 1A, and 0.3% of the controls. Eating or tasting raw or medium done pork was a significant risk factor for pathogenic YE bio/serotype infection (OR 6.6; 95% CI 1.7-24.9 as well as eating in a canteen (OR 3.5; 95% CI 1.6-7.9. Imported fruits and berries were associated with increased risk of YE BT 1A finding. Conclusions The symptoms of the patients with YE BT 1A differed from yersiniosis caused by the classic pathogenic YE bio/serotypes. In addition, the patients with YE BT 1A had more protracted gastrointestinal disorders and unspecific complaints. Small children were overrepresented in classic pathogenic bio/serotypes while in BT 1A or YE-like species were not found among children younger than two years. This suggests the lacking virulence of the BT 1A strains. We can not, however, rule out the possibility that some strains of genetically heterogeneous group of BT 1A may cause an illness.

An octanuclear molybdenum(VI) complex containing coordinatively bound 4,4'-di-tert-butyl-2,2'-bipyridine, [Mo8O22(OH)4(di-tBu-bipy)4]: synthesis, structure, and catalytic epoxidation of bio-derived olefins.

Science.gov (United States)

Amarante, Tatiana R; Neves, Patrícia; Tomé, Cátia; Abrantes, Marta; Valente, Anabela A; Paz, Filipe A Almeida; Pillinger, Martyn; Gonçalves, Isabel S

2012-03-19

The reaction of [MoO(2)Cl(2)(di-tBu-bipy)] (1) (di-tBu-bipy = 4,4'-di-tert-butyl-2,2'-bipyridine) with water at 100-120 °C in a Teflon-lined stainless steel autoclave, in an open reflux system, or in a microwave synthesis system gave the octanuclear complex [Mo(8)O(22)(OH)(4)(di-tBu-bipy)(4)] (2) as a microcrystalline powder in good yields. Single crystals of 2 suitable for X-ray diffraction were obtained by the reaction of MoO(3) and di-tBu-bipy in water at 160 °C for 3 days. The molecular structure of 2 comprises a purely inorganic core, Mo(4)O(8)(μ(3)-OH)(2)(μ(2)-O)(2), attached to two peripheral oxo-bridged binuclear units, Mo(2)O(4)(μ(2)-O)(2)(OH)(di-tBu-bipy)(2). The inorganic core is composed of a unique assembly of four {MoO(5)} distorted square pyramids connected to each other via edge-sharing. Overall, the octanuclear complex adopts a highly distorted form strongly resembling an "S"-shaped molecular unit. Complex 2 was applied in the catalytic epoxidation of the biorenewable olefins DL-limonene (Lim) and methyl oleate (Ole), using tert-butylhydroperoxide (TBHP) as an oxygen donor, under mild reaction conditions (55 °C, air). The reactions of Lim and Ole gave the respective epoxide monomers in fairly high selectivities at high conversions (89% 1,2-epoxy-p-menth-8-ene selectivity at 96% Lim conversion; 99% methyl 9,10-epoxystearate selectivity at 94% Ole conversion, reached within 24 h reaction). Iodometric titrations revealed no measurable "non-productive" decomposition of TBHP. © 2012 American Chemical Society

Latvijas sabiedrisko attiecību aģentūru prakse plānotas krīzes komunikācijas vadīšanā

OpenAIRE

Štokmane, Linda

2014-01-01

Darba nosaukums ir „Latvijas sabiedrisko attiecību aģentūru prakse plānotas krīzes komunikācijas vadīšanā”. Pētījuma problēma - vai krīzes situācijām iespējams sagatavoties un kā iepriekš plānota un sagatavota komunikācija spēj palīdzēt efektīvāk vadīt krīzes situācijas? Bakalaura darba mērķis ir izpētīt, kāda ir Latvijas sab iedrisko attiecību aģentūru prakse un pieredze krīzes komunikācijas plānošanā un vadīšanā. Darba teorētiskā bāze, galvenokārt, balstīta uz situatīvo krīzes komunikāci...

Piedošanas, subjektīvās labklājības un uztvertās attiecību kvalitātes saistība

OpenAIRE

Plauča, Ilze

2010-01-01

Darbā tiek apskatīti piedošanas, uztvertās attiecību kvalitātes un subjektīvās labklājības saistība. Piedošana tiek aplūkota M.Makkuloka (McCullough) izstrādātā modeļa ietvaros, ka piedošana ir atriebības, izvairīšanās un labvēlības motivācijas izmaiņu komplekss. Uztvertās attiecību kvalitātes komponentes ir apmierinātība ar attiecībām , nodošanās, intimitāte jeb tuvība, uzticēšanās, kaislība un mīlestība (Fletcher et al). Subjektīvās labklājības modelis tiek aplūkots Dīnera (Diener) teor...

(nBuCp)2ZrCl2-catalyzed Ethylene-4M1P Copolymerization: Copolymer Backbone Structure, Melt Behavior, and Crystallization

KAUST Repository

Atiqullah, Muhammad

2016-01-08

The judicious design of methylaluminoxane (MAO) anions expands the scope for developing industrial metallocene catalysts. Therefore, the effects of MAO anion design on the backbone structure, melt behavior, and crystallization of ethylene−4-methyl-1-pentene (E−4M1P) copolymer were investigated. Ethylene was homopolymerized, as well as copolymerized with 4M1P, using (i) MAO anion A (unsupported [MAOCl2]−) premixed with dehydroxylated silica, (nBuCp)2ZrCl2, and Me2SiCl2; and (ii) MAO anion B (Si−O−Me2Si−[MAOCl2]−) supported with (nBuCp)2ZrCl2 on Me2SiCl2-functionalized silica. Unsupported Me2SiCl2, opposite to the supported analogue, acted as a co-chain transfer agent with 4M1P. The modeling of polyethylene melting and crystallization kinetics, including critical crystallite stability, produced insightful results. This study especially illustrates how branched polyethylene can be prepared from ethylene alone using particularly one metallocene-MAO ion pair, and how a compound, that functionalizes silica as well as terminates the chain, can synthesize ethylene−α-olefin copolymers with novel structures. Hence, it unfolds prospective future research niches in polyethyne systhesis. This article is protected by copyright. All rights reserved.

První regulérní výzkum areálu zaniklého hradu v Buštěhradu

Czech Academy of Sciences Publication Activity Database

Durdík, Tomáš; Juřina, P.

2007-01-01

Roč. 68, - (2007), s. 55 ISSN 1211-992X. [Archeologické výzkumy v Čechách 2006. Praha, 11.04.2007-12.04.2007] R&D Projects: GA MK DB06P01OPP004 Institutional research plan: CEZ:AV0Z80020508 Keywords : castle * castellology * Buštěhrad * architecture * medieval archeology * Middle Ages Subject RIV: AC - Archeology, Anthropology, Ethnology

Volatile Compounds and Sensory Profiles of Monovarietal Virgin Olive Oil from Buža, Črna and Rosinjola Cultivars in Istria (Croatia

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Barbara Sladonja

2012-01-01

Full Text Available The volatile compounds found in virgin olive oil, mainly C6 and C5 volatile compounds biogenerated from polyunsaturated fatty acids through the lipoxygenase pathway, are responsible for their particular aroma. The composition of volatile compounds in olive oil depends on the cultivar, the ripening degree of the fruits and processing conditions. Among many different autochthonous cultivars in Istria (Croatia, some of the most prevalent are Buža, Črna and Rosinjola. The volatiles and sensory characteristics of their monovarietal virgin olive oil are little known. Therefore, fruits from these three cultivars were handpicked at the same ripening degree and processed under the same conditions. Quantitative descriptive sensory analysis of monovarietal virgin olive oil was carried out by the panel. Volatile composition was evaluated by headspace solid phase microextraction-gas chromatography, previously optimized and validated. The main parameters affecting effectiveness, time and temperature of extraction were optimized. The extraction procedure showed detection and quantification limits, as well as linear ranges adequate for the analysis of selected volatile compounds. Good precision was obtained both in terms of intra-day repeatability (relative standard deviations generally lower than 7 % and inter-day precision. The tested types of monovarietal olive oil showed different volatile profiles, although E-2-hexenal was the main compound in all samples. Buža oil was the richest in total C6 and C5 volatile compounds. The results show that the most important contributors to the olive oil aroma (odour activity value >1.0 were 1-penten-3-one, E-2-hexenal, hexanal, hexanol, Z-3-hexen-1-ol and Z-2-penten-1-ol. These chemical findings were compared with those provided by the panel test. Buža had the highest intensity of sensory characteristic 'other ripe fruits' and Rosinjola had the highest intensity of sensory characteristic 'bitter'. All results show

Results of test operation of the thyristor power supply for the BU-70 proton synchrotron ring electromagnet

International Nuclear Information System (INIS)

Vasil'ev, S.N.; Gusev, G.I.; Dan'shin, V.P.; Eliseenko, A.I.

1985-01-01

The thyristor converter put into operation in the course of reconstruction of the power supply of the BU-70 synchrotron ring electromagnet is described. The converter is designed for maximum current I=5 kA and voltage 2x10 kV and consists of four three-phase bridge rectifiers connected in parallel in the equivalent twelve-phase circuit. The total number of thyristors - 2304. The thyristor power supply operated over 7000 h. The conclusion is drawn that the use of thyristors allows one to sharply reduce the time of system tuning for nominal operation mode, reduce water consumption for convertercooling and considerably improve the working conditions ofthe maintenance personnel

Sebze Püresi ile Üretilen Yoğurtların Tekstürel ve Duyusal Özelliklerinin Belirlenmesi

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Tülay Özcan

2016-07-01

Full Text Available Bu çalışmada kontrol (K; balkabağı (YBK, havuç (YHA, bezelye (YBE ve yeşil kabak püreli (YYK yoğurt olmak üzere 5 farklı set tipi yoğurt üretilmiştir. Sebzeli yoğurtlarda bulunan diyet liflerinin bakteri gelişmesini teşvik eden potansiyel etkisi sonucu Streptococcus thermophilus ile Lactobacillus delbrueckii subsp. bulgaricus sayılarının arttığı saptanmıştır. Yoğurtların sebze püreleri ile zenginleştirilmesinin pH, titrasyon asitliği, serum ayrılması, duyusal özelikler ile sertlik, iç yapışkanlık, konsistens ve viskozite indeksi gibi tekstürel özellikler üzerinde etkili olduğu gözlenmiştir. Havuç püresi ile üretilen yoğurtlarda viskozite, konsistens ve sertliğin yüksek olduğu saptanırken, yeşil kabak ilaveli olanlar daha zayıf tekstürel özellikler göstermiştir. Sonuç olarak sebze püresi ilavesinin set tipi yoğurtlarda tekstürel özelliklerinin iyileştirilmesi konusunda önemli rol oynadığı ve fonksiyonel süt ürünlerinin geliştirilmesinde kullanılabileceği belirlenmiştir.

AN UNCOMPLETED MATHNAWI DUE TO THE DEATH OF IT’S AUTHOR: LEYLÂ VÜ MECNÛN (LAYLA AND MADJNUN MÜELLİFİNİN ÖLÜMÜYLE YARIM KALMIŞ BİR MESNEVÎ: LEYLÂ VÜ MECNÛN

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Hüsrev AKIN

2009-10-01

Full Text Available Mathnawis are types of verse in which such subjects as legends and stories are narrated in our ancient literature. Mathnawis whose early examples orginate in Persian literature are also seen in Turkish literature from the same source. In our literature, mathnawis were commonly written between XIII and XVIII centuries. One of the subjects that has been dealt with is the story of Layla and Madjnun. This story is the one that is most treated among the ones with two lovers. One of the authors that tells this story in his work is Kafzâde Fâizî. But, when he dies at an early age, the work remains to be completed. In the present study, being an unfinished work, the introduction and the translation of the work on which there has been no serious comment is given. Mesneviler, eski edebiyatımızda destan, menkıbe gibi uzun konuların anlatıldığı nazım biçimidir. İlk örnekleri Fars edebiyatında görülen mesnevi Türk edebiyatına da oradan geçmiştir. Edebiyatımızda mesneviler yoğun olarak XIII. ve XVIII. yüzyıllar arasında yazılmıştır. Bu mesnevilerde sıklıkla ele alınan konulardan birisi de Leylâ ile Mecnûn hikâyesidir. Bu hikâye iki âşık karakterli hikâyeler içinde en çok işleneni olmuştur. Bunu eserinde anlatan şâirlerden birisi de Kafzâde Fâizî’dir. Fakat Kafzâde Fâizî, genç yaşta ölünce bu eser yarım kalmıştır. Bu makalede, tamamlanmamış bir eser olduğu için bugüne kadar üzerinde ciddi olarak durulmayan bu eserin tanıtımı ve çeviri yazısı yapılmıştır.

Āzijas vērtību nozīme Austrumāzijas demokrātijā uz Japānas, Dienvidkorejas un Taizemes piemēra

OpenAIRE

Murašova, Kristīne

2017-01-01

Maģistra darba tēmas nosaukums ir “Āzijas vērtību nozīme Austrumāzijas demokrātijā uz Japānas, Dienvidkorejas un Taizemes piemēra”. Šis darbs iekļauj pētījumu par Āzijas vērtību nozīmi Austrumāzijas demokrātijā. Pētījumā tiek sniegta atbilde, vai Āzijas vērtības ir pretrunā ar demokrātiju, salīdzinot šīs vērtības ar universālajām vērtībām. Tiek salīdzināts Japānas demokrātijas modelis ar Dienvidkorejas un Taizemes demokrātijas modeļiem, un sniegta atbilde, vai Japāna ir vienīgā Austrumāzijas ...

Jūrmalas pilsētas domes īpašuma izmantošanas nosacījumi un problēmas privāto tiesību jomā

OpenAIRE

Millers, Andris

2008-01-01

Darbā aplūkoti problēmjautājumi, kas rodas, ja Jūrmalas pilsētas dome izmanto tās īpašumu privāto tiesību jomā. To cēlonis ir nepabeigtais privatizācijas process, nepilnīgais tiesiskais regulējums pašvaldības īpašuma iznomāšanā un nesakārtotā normatīvā bāze tādu modernu publisko projektu finansēšanai kā privātā un publiskā partnerība. Autors piedāvā veikt izmaiņas normatīvajos aktos, skaidro jau esošo tiesību normu pareizu piemērošanu un izsaka savus priekšlikumus sekmīg...

SEMANTIC CONTENT OF PRONOUNS IN TURKEY TURKISH TÜRKİYE TÜRKÇESİNDE ZAMİRLERİN ANLAM YÜKÜ

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Ahmet AKÇATAŞ

2010-10-01

Full Text Available The present study aims to examine the semantic content of pronouns in Turkey Turkish. The definition of the term “pronouns” was reconsidered in this sense, and it was revealed that a new classification should be made. Furthermore, the term “substitution” was re-examined, and it was concluded that “all words denote an aspect of pronouns since they correspond to concepts of the real world”. Bearing a paradigmatic structure, pronouns attain the real world knowledge by using other glossemes, thereby creating semantic content, which is named concretization. The meaning of a pronoun is determined by the context in the process of such concretion. The intention referred to in the text shapes the semantic content of pronouns. The distance between a pronoun and its target also plays a role in assuming a meaning. Demonstrative and interrogative pronouns summarizes the information in one or more sentences, thus enabling them to be used for different aims. The incorporation of such usage of pronouns in Turkey Turkish into curriculum will yield many benefits with respect to reading, comprehension, and education. Türkiye Türkçesinde zamirlerin anlam yükünün incelendiği bu çalışmada zamir teriminin tanımı yeniden ele alınmış ve buna göre bir sınıflama yapılmasının gerekliliği belirlenmiştir. Ayrıca “yerine geçme” tabiri yeniden ele alınarak, “gerçek dünyadaki kavramların karşılığı olduğu için bütün kelimelerin zamir yönü olduğu” sonucuna varılmıştır. Paradigmatik bir yapıya sahip olan zamirlerin, başka dilbirimlerini kullanarak gerçek dünya bilgisine ulaştıkları ve anlam yüklerini oluşturdukları belirlenmiştir. Buna da somutlaştırma denilmektedir. Zamirin anlamını, bu somutlaşma sırasında metnin bağlamı belirler. Metinde kastedilen niyet, zamirin anlam yükünü belirler. Gönderimle ise zamirlerin anlamları düzenlenir. Zamirin hedefiyle arasındaki mesafesi de onun anlamı y

Üzüm Çekirdeği Tozu ve Peynir Altı Suyu Tozunun Tavuk Nugget Kalitesi Üzerine Etkileri

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Ece Cagdas

2015-02-01

Full Text Available Bu çalışma kapsamında; buğday unu, mısır unu, tuz ve kabartma ajanı ile hazırlanan basit kaplama hamuruna değişik oranlarda üzüm çekirdeği tozu (GSP eklenerek kaplanan ve peynir altı suyu tozu çözeltisine (WPS daldırılarak kaplanan tavuk eti parçalarının ön kızartma işleminden sonra nem, protein, yağ ve yüzeyde yapışma miktarları belirlenmiştir. Bunların yanı sıra, doku, taramalı elektron mikroskobu (SEM ve tiyobarbitürik asit (TBA analizleri yapılmıştır. Yapılan çalışma sonucunda GSP miktarı arttıkça nem (%66.20±0.71 – 68.22±0.38, protein (%16.16±1.36 – 19.73±1.40 ve yüzeyde yapışma miktarı (%26.27±0.43 – 36.13±0.71 artış gösterirken yağ miktarında (%8.18±0.17 – 4.78±0.54 azalış meydana gelmiştir. En düşük yağ miktarları WPS’ye daldırılarak hazırlanan örneklerde bulunmuştur. Uygulama yapılan örneklerde ön kızartma işleminden sonra da antioksidan aktivite gözlenmiş ve uygulama yapılan tüm örneklerin TBA değerleri (23.30±1.61 – 27.17±1.12 mg MDA/kg kontrol ile karşılaştırıldığında daha düşük seviyelerde olsa da önemli bir fark belirlenmemiştir (P>0.05. Elde edilen sonuçlara göre kaplama harcı malzemesi olarak GSP kullanımı ve WPS’ye daldırma işlemi kaplama harcının kalitesinin geliştirilmesinde bir potansiyele sahiptir.

Bibliography of Soviet Laser Developments, Number 55. September-October 1981.

Science.gov (United States)

1983-01-01

Boldeskul , I.Ye., and A.Ye. Boldeskul (0). Fluorescence and resonant R-amanspctra1 probes in studies on the dynamics of biological and micellar...AKAYEV A 45 BOLDESKUL I YE 72 AKHMANOV S A 87 PAPADZHAN YE 1 79 BOLGAROV L N 11 AKHMEDZHANOV I M 24 BABARSKOV YE V 84 BOL’SHOV L A 84 AKHSAKHALYAN A D

Mārketinga vides faktori un to ietekme uz uzņēmuma darbību

OpenAIRE

Čačika, Anastasija

2012-01-01

Bakalaura darba nosaukums ir „Mārketinga vides faktori un to ietekme uz uzņēmuma darbību”. Bakalaura darba mērķis ir veikt mārketinga vides analīzi, kā arī novērtēt iekšējas un ārējas mārketinga vides ietekmi uz „Ave Trans Group” uzņēmuma darbību. Darbā tiek apskatīti mārketinga vides teorētiskie aspekti, kā arī holdinga kompānijas „Ave Trans Group” mārketinga vidi ietekmējošie faktori, un ir piedāvāta dotā uzņēmuma mārketinga vides analīze, kā arī veikta anketēšana un anketu analīze. ...

Ab initio dynamics trajectory study of the heterolytic cleavage of H2 by a Lewis acid [B(C6F5)3] and a Lewis base [P(tBu)3

Science.gov (United States)

Pu, Maoping; Privalov, Timofei

2013-04-01

Activation of H2 by a "frustrated Lewis pair" (FLP) composed of B(C6F5)3 and P(tBu)3 species has been explored with high level direct ab initio molecular dynamics (AIMD) simulations at finite temperature (T = 300 K) in gas phase. The initial geometrical conditions for the AIMD trajectory calculations, i.e., the near attack conformations of FLP + H2, were devised using the host-guest model in which suitable FLP conformations were obtained from the dynamics of the B(C6F5)3/P(tBu)3 pair in gas phase. AIMD trajectory calculations yielded microscopic insight into effects which originate from nuclear motion in the reacting complex, e.g., the alternating compression/elongation of the boron-phosphorous distance and the change of the pyramidality of boron in B(C6F5)3. The ensemble averaged trajectory analysis has been compared with the minimum energy path (MEP) description of the reaction. Similar to MEP, AIMD shows that an attack of the acid/base pair on the H-H bond gives rise to the polarization of the H2 molecule and as a consequence generates a large dipole moment of the reacting complex. The MEP and AIMD portrayals of the reaction are fundamentally different in terms of the magnitude of the motion of nuclei in B(C6F5)3 and P(tBu)3 during the H2 cleavage. In the AIMD trajectory simulations, geometries of B(C6F5)3 and P(tBu)3 appear as nearly "frozen" on the short time scale of the H2 cleavage. This is contrary to the MEP picture. Several of the concepts which arise from this work, e.g., separation of time scales of nuclear motion and the time-dependence of the donor-acceptor interactions in the reacting complex, are important for the understanding of chemical reactivity and catalysis.

Mononuclear phagocytes contribute to intestinal invasion and dissemination of Yersinia enterocolitica.

Science.gov (United States)

Drechsler-Hake, Doreen; Alamir, Hanin; Hahn, Julia; Günter, Manina; Wagner, Samuel; Schütz, Monika; Bohn, Erwin; Schenke-Layland, Katja; Pisano, Fabio; Dersch, Petra; Autenrieth, Ingo B; Autenrieth, Stella E

2016-09-01

Enteropathogenic Yersinia enterocolitica (Ye) enters the host via contaminated food. After colonisation of the small intestine Ye invades the Peyer's patches (PPs) via M cells and disseminates to the mesenteric lymph nodes (MLNs), spleen and liver. Whether Ye uses other invasion routes and which pathogenicity factors are required remains elusive. Oral infection of lymphotoxin-β-receptor deficient mice lacking PPs and MLNs with Ye revealed similar bacterial load in the spleen 1h post infection as wild-type mice, demonstrating a PP-independent dissemination route for Ye. Immunohistological analysis of the small intestine revealed Ye in close contact with mononuclear phagocytes (MPs), specifically CX3CR1(+) monocyte-derived cells (MCs) as well as CD103(+) dendritic cells (DCs). This finding was confirmed by flow cytometry and imaging flow cytometry analysis of lamina propria (LP) leukocytes showing CD103(+) DCs and MCs with intracellular Ye. Uptake of Ye by LP CD103(+) DCs and MCs was dependent on the pathogenicity factor invasin, whereas the adhesin YadA was dispensable as demonstrated by Ye deletion mutants. Furthermore, Ye were found exclusively associated with CD103(+) DCs in the MLNs from wild-type mice, but not from CCR7(-/-) mice, demonstrating a CCR7 dependent transport of Ye by CD103(+) DCs from LP to the MLNs. In contrast, dissemination of Ye to the spleen was dependent on MCs as significantly less Ye could be recovered from the spleen of CX3CR1(GFP/GFP) mice compared to wild-type mice. Altogether, MCs and CD103(+) DCs contribute to immediate invasion and dissemination of Ye. This together with data from other bacteria suggests MPs as general pathogenic entry site in the intestine. Copyright © 2016 Elsevier GmbH. All rights reserved.

Black Hole on a Chip: Proposal for a Physical Realization of the Sachdev-Ye-Kitaev model in a Solid-State System

Directory of Open Access Journals (Sweden)

D. I. Pikulin

2017-07-01

Full Text Available A system of Majorana zero modes with random infinite-range interactions—the Sachdev-Ye-Kitaev (SYK model—is thought to exhibit an intriguing relation to the horizons of extremal black holes in two-dimensional anti–de Sitter space. This connection provides a rare example of holographic duality between a solvable quantum-mechanical model and dilaton gravity. Here, we propose a physical realization of the SYK model in a solid-state system. The proposed setup employs the Fu-Kane superconductor realized at the interface between a three-dimensional topological insulator and an ordinary superconductor. The requisite N Majorana zero modes are bound to a nanoscale hole fabricated in the superconductor that is threaded by N quanta of magnetic flux. We show that when the system is tuned to the surface neutrality point (i.e., chemical potential coincident with the Dirac point of the topological insulator surface state and the hole has sufficiently irregular shape, the Majorana zero modes are described by the SYK Hamiltonian. We perform extensive numerical simulations to demonstrate that the system indeed exhibits physical properties expected of the SYK model, including thermodynamic quantities and two-point as well as four-point correlators, and discuss ways in which these can be observed experimentally.

New line selected from irradiated cuttings of sweet potato

International Nuclear Information System (INIS)

Lu Shuyun; Wu Chongguang; Li Weiji; Feng Qihuan

1992-01-01

Some clonal lines of resistance to black rot were obtained from M 1 V 3 of Xu-18 variety. Through some regional tests, provincial yield trial and production test, the mutant line Nong-Da 601 (12-11-8) as spring sweet potato showed a better yield than the control, the dry matter content of Nong-Da 601 was also better than that of control, further more, the resistance to black rot of mutant selected in M 1 V 3 could be passed onto their progeny. The analysis of esterase isozyme showed zymogram variation between Nong-Da 601 and Xu-18. From the observation of the root tip cells, the chromosome bridge appeared obviously after irradiation, but the frequency of chromosome aberration in M 1 V 6 was decreased almost to the level of control (Xu-18). It seems that the changes of disease resistance from susceptible to resistant by irradiation was not due to chromosome aberration but due to gene mutation

Development, Validation, and Interlaboratory Evaluation of a Quantitative Multiplexing Method To Assess Levels of Ten Endogenous Allergens in Soybean Seed and Its Application to Field Trials Spanning Three Growing Seasons.

Science.gov (United States)

Hill, Ryan C; Oman, Trent J; Wang, Xiujuan; Shan, Guomin; Schafer, Barry; Herman, Rod A; Tobias, Rowel; Shippar, Jeff; Malayappan, Bhaskar; Sheng, Li; Xu, Austin; Bradshaw, Jason

2017-07-12

As part of the regulatory approval process in Europe, comparison of endogenous soybean allergen levels between genetically engineered (GE) and non-GE plants has been requested. A quantitative multiplex analytical method using tandem mass spectrometry was developed and validated to measure 10 potential soybean allergens from soybean seed. The analytical method was implemented at six laboratories to demonstrate the robustness of the method and further applied to three soybean field studies across multiple growing seasons (including 21 non-GE soybean varieties) to assess the natural variation of allergen levels. The results show environmental factors contribute more than genetic factors to the large variation in allergen abundance (2- to 50-fold between environmental replicates) as well as a large contribution of Gly m 5 and Gly m 6 to the total allergen profile, calling into question the scientific rational for measurement of endogenous allergen levels between GE and non-GE varieties in the safety assessment.

Leaf Beetles (Coleoptera ; Chrysomelidae) in the Campus and Agricultural Research Stations of Chiang Mai University, Thailand

OpenAIRE

Umemura, S; Tayutivutukul, J; Nakamura, H

2005-01-01

Qualitative surveys of leaf beetles were conducted at 5 survey sites (Chiang Mai University, Mae Hia Staion, Chang Kien Station, Nong Hoi Station, Suburb of Chiang Mai City) in Chiang Mai, Thailand using sweeping and beating methods from October 19th to October 30th, 2003. A total of 24 species of 8 subfamilies was collected from five survey sites ; 11 species, 3 species, 2 species, 11 species, 4 species from Chiang Mai University, Mae Hia Station, Chang Kien Station, Nong Hoi Station, Suburb...

Characteristics and risk factors of oral mucositis after allogeneic stem cell transplantation with FLU/MEL conditioning regimen in context with BU/CY2.

Science.gov (United States)

Vokurka, S; Steinerova, K; Karas, M; Koza, V

2009-11-01

The fludarabine (FLU)/melphalan (MEL) conditioning regimen containing FLU and high-dose MEL was analyzed in comparison with the BU/CY2 regimen to characterize oral mucositis (OM) and risk factors. OM incidence significantly varied between BU/CY2 and FLU/MEL (100 vs 78%, P=0.004), but the incidence of severe OM grades 3-4 WHO and kinetics of OM were fully comparable. Patients with OM persisting on day +21 had more acute GVHD (68 vs 32%, P=0.005), which tended to occur earlier than among those without such prolonged OM. Multivariate analysis showed significant dependency of acute GVHD on severity and prolonged duration of OM and significant correlation between OM severity and its prolonged duration. Body surface area-based dosing in the FLU/MEL regimen led to a wide range of MEL doses administered per kilogram body weight (2.5-5.2 mg/kg, median 3.5). In multivariate analysis, MEL dose per kilogram of body weight was found to be a significant predictor of OM incidence and severity. Female gender and lower body mass index were less important variables than the fact that the actual dose of MEL administered per kilogram of body weight was relatively high when the dosage was calculated on the basis of body surface area.

Fe4 cluster and a buckled macrocycle complex from the reduction of [(dmgBF2)2Fe(L)2] (L = MeCN, (t)Bu(i)NC).

Science.gov (United States)

Rose, Michael J; Winkler, Jay R; Gray, Harry B

2012-02-20

We report the syntheses, X-ray structures, and reductive electrochemistry of the Fe(II) complexes [(dmgBF(2))(2)Fe(MeCN)(2)] (1; dmg = dimethylglyoxime, MeCN = acetonitrile) and [(dmgBF(2))Fe((t)Bu(i)NC)(2)] (2; (t)Bu(i)NC = tert-butylisocyanide). The reaction of 1 with Na/Hg amalgam led to isolation and the X-ray structure of [(dmgBF(2))(2)Fe(glyIm)] (3; glyIm = glyimine), wherein the (dmgBF(2))(2) macrocyclic frame is bent to accommodate the binding of a bidentate apical ligand. We also report the X-ray structure of a rare mixed-valence Fe(4) cluster with supporting dmg-type ligands. In the structure of [(dmg(2)BF(2))(3)Fe(3)((1)/(2)dmg)(3)Fe(O)(6)] (4), the (dmgBF(2))(2) macrocycle has been cleaved, eliminating BF(2) groups. Density functional theory calculations and electron paramagnetic resonance data are in accordance with a central Fe(III) ion surrounded by three formally Fe(II)dmg(2)BF(2) units.

BİR YÖNETİM UYGULAMASININ TÜRKİYE BAĞLAMINDA YENİDEN İNŞASI: KURUMSAL YÖNETİM

OpenAIRE

KAROĞLU, Ertuğrul; ÇAPKULAÇ, Onur

2016-01-01

Araştırmanın amacı Türkiye’deki kurumsal yönetim uygulamalarının inşa edilmesinde kullanılan söylemi ortaya koymaktır. Bu amaç doğrultusunda TÜSİAD’ın (Türk Sanayicileri ve İşadamları Derneği) ve TKYD’nin (Türkiye Kurumsal Yönetim Derneği) 2002 ile 2015 yılları arasındaki kurumsal yönetim ile ilgili söylemleri Aristo’nun Ethos, Pathos ve Logos retorik stratejilerine göre analiz edilmiştir. TÜSİAD ve TKYD’nin kurumsal yönetimin inşası noktasındaki söylemlerinin analizi sonucunda elde edilmiş o...

Effect of progressive drought stress on growth, leaf gas exchange, and antioxidant production in two maize cultivars.

Science.gov (United States)

Anjum, Shakeel Ahmad; Tanveer, Mohsin; Ashraf, Umair; Hussain, Saddam; Shahzad, Babar; Khan, Imran; Wang, Longchang

2016-09-01

Drought stress is one of the major environmental factors responsible for reduction in crop productivity. In the present study, responses of two maize cultivars (Rung Nong 35 and Dong Dan 80) were examined to explicate the growth, yield, leaf gas exchange, leaf water contents, osmolyte accumulation, membrane lipid peroxidation, and antioxidant activity under progressive drought stress. Maize cultivars were subjected to varying field capacities (FC) viz., well-watered (80 % FC) and drought-stressed (35 % FC) at 45 days after sowing. The effects of drought stress were analyzed at 5, 10, 15, 20, ad 25 days after drought stress (DAS) imposition. Under prolonged drought stress, Rung Nong 35 exhibited higher reduction in growth and yield as compared to Dong Dan 80. Maize cultivar Dong Dan 80 showed higher leaf relative water content (RWC), free proline, and total carbohydrate accumulation than Run Nong 35. Malondialdehyde (MDA) and superoxide anion were increased with prolongation of drought stress, with higher rates in cultivar Run Nong 35 than cultivar Dong Dan 80. Higher production of superoxide dismutase (SOD), peroxidase (POD), and catalase (CAT) and glutathione reductase (GR) resulted in improved growth and yield in Dong Dan 80. Overall, the cultivar Dong Dan 80 was better able to resist the detrimental effects of progressive drought stress as indicated by better growth and yield due to higher antioxidant enzymes, reduced lipid peroxidation, better accumulation of osmolytes, and maintenance of tissue water contents.

from left to right : Mr Michel Della Negra (Last spokeperson of CMS), Prof. Tejinder ("Jim") Virdee (actual spokeperson of CMS), Mr Robert Aymar (CERN Director General) and Mr Sigurd Lettow (Chief Financial Officer of CERN) assist to the Lowering of the final element (YE-1) of the Compact Muon Solenoid (CMS) detector into its underground experimental cavern.

CERN Multimedia

Maximilien Brice

2008-01-01

from left to right : Mr Michel Della Negra (Last spokeperson of CMS), Prof. Tejinder ("Jim") Virdee (actual spokeperson of CMS), Mr Robert Aymar (CERN Director General) and Mr Sigurd Lettow (Chief Financial Officer of CERN) assist to the Lowering of the final element (YE-1) of the Compact Muon Solenoid (CMS) detector into its underground experimental cavern.

TÜRKİYE MUHASEBE STANDARDI - 8 VE TEKDÜZEN HESAP PLANI ÇERÇEVESİNDE, FRANCHISING İŞLEMLERİNİN MUHASEBELEŞTİRİLMESİ

OpenAIRE

Özulucan, Abitter

2010-01-01

Özet: Franchising, mal ve hizmetlerin tüketicilere etkin bir şekildeaktarılmasını sağlayabilmek için uygulanan, bir pazarlama sistemidir. Busistemde en az iki taraf bulunmaktadır. Bunlardan birincisi, diğer işletmelereimtiyaz hakkı veren (ranchisor'dır. Diğeri ise, mümkün olduğu kadar dahafazla pazar payını elde etmeye çalışan franchisee'dir.Bu çalışmada, öncelikle franchising kavramı detaylı olarak a&...

Mācību līdzeklis skaitļu teorijā pamatskolas skolēniem

OpenAIRE

Sirica, Dmitrijs

2009-01-01

Maģistra darbā ir izstrādāts mācību līdzeklis skaitļu teorijā pamatskolas skolēniem. Darbā apkopoti pēdējo gadu dažādu līmeņu Latvijas matemātikas olimpiāžu uzdevumi skaitļu teorijā un doti izvērsti to atrisinājumi. Darbs paredzēts galvenokārt šādiem mērķiem: - palīgmateriāls matemātikas skolotājiem, gatavojot skolēnus matemātikas olimpiādēm ; - palīgmateriāls skolēniem, lai apgūtu nestandarta uzdevumu risināšana metodes skaitļu teorijā. Darbs satur arī mate...

Buškové z Velhartic. Historie pánů z Velhartic ve 14. století ve světle kartoték Augusta Sedláčka

Czech Academy of Sciences Publication Activity Database

Doležalová, Eva

2015-01-01

Roč. 18, č. 2 (2015), s. 181-191 ISSN 0862-979X R&D Projects: GA MK(CZ) DF12P01OVV019 Keywords : lord of Velhartice * 14th century * Czech lands * Charles IV * Bušek of Velhartice Subject RIV: AB - History

Design, calculation and testing on mock-up of B(U) f type LR 56 packaging for radioactive liquid effluent transport

International Nuclear Information System (INIS)

Belaud; Leconnetable; Daspet; Tombini; Tanguy

1986-06-01

Transport of radioactive acid liquid effluents are effected on tank truck inside nuclear center of the CEA. The cylindrical packaging type B(U) f has a capacity of 4,000l, a maximum permissible activity of 110 T Bq (3x10 4 Ci) and comprises a central element for liquid effluent containment to prevent contamination of environment and peripheral elements for mechanical, biological and thermal protection. This packaging is fixed on a trailer associated with a control box. Design and equipment of the packaging are studied for a maximum safety and in accordance with regulations [fr

Performance evaluation of Siemens E.CAM(R) SPECT system at Korle-Bu Teaching Hospital (Ghana)

International Nuclear Information System (INIS)

Sosu, E.K.; Hasford, F.; Amuasi, J.H.

2011-01-01

Performance evaluation tests on Siemens e.cam(R) Signature Series Single Photon Emission Computed Tomography (SPECT)System at Korle-Bu Teaching Hospital (Ghana) were conducted for compliance with Manufacturer's specifications and user's requirements. The tests were performed according to National Electrical Manufacturer's Association protocols, and different measuring instruments and phantoms containing 99m-Tc were used. Extrinsic uniformity, system energy resolution, system spatial resolution (without scattering), detector shield leakage and system planar sensitivity were evaluated. The system energy resolution measured was 9.38 % as against manufacturer's specification of ≤ 9.9 %, Planar sensitivity value measured was 232.92 c/min/mCi while manufacturers' specification was 202 c/min/mCi, and detector shield leakage values measured were 0.001 %, 0.002 % and 0.025 % against an accepted value of < 1 %. The performance evaluation confirmed that the system met requirements for clinical nuclear medicine imaging, and the values could be used as database for future quality control measurements. (au)

De Ella a Él: caras y máscaras en la “novela” de Mercedes Pinto (1926 y en la película de Luis Buñuel (1952

Directory of Open Access Journals (Sweden)

Heitz, Françoise

2011-04-01

Full Text Available Mercedes Pinto’s itinerary took her from the Canary Islands, where she was born, to Mexico, after a passage through Uruguay. She first met success through her writings and cultural activities, and was then forgotten. However, her book –published in Montevideo in 1926– was adapted for the cinema by Luis Buñuel in 1952, and the film gave new life to this autobiographical “novel” He. If self-fiction prevails in the literary work, with the clear commitment of a feminist who takes a stand in favour of freedom –the freedom to divorce in that case–, in Buñuel’s Mexican film the study of the clinical case of paranoia acquires a new form of complexity. The attack on a parasitic bourgeoisie is united to the subversion of the melodramatic genre, with a false happy end which distorts established codes and lets the principle of doubt impose itself. In the same way the exploration of sexual roles, heir to the surrealistic trend, is devoid of any manichean simplification and stands out as a fascinating object for any hermeneutic approach.Mercedes Pinto, cuya trayectoria se desarrolló desde Canarias, su tierra de nacimiento, hasta México, pasando por Uruguay, conoció el éxito por sus escritos y actividades culturales y luego quedó sumida en el olvido. Sin embargo, la adaptación de su “novela” autobiográfica Él (Montevideo, 1926 a la gran pantalla por Luis Buñuel en 1952, le deparó otra vida al libro. Si en la obra literaria prevalece la autoficción y su claro compromiso feminista a favor del divorcio, adquiere nueva complejidad en la película mexicana de Buñuel el estudio del caso clínico de la paranoia. Al ataque a una burguesía parasitaria se une una subversión del género del melodrama, cuyo falso final feliz pervierte los códigos establecidos, dejando que se imponga el principio de duda. Asimismo, la exploración de los roles sexuales, heredera de la corriente surrealista, rehúye toda simplificación maniquea y se

ÇİN’E AİT İMGE VE MOTİFLERİN ŞEHNÂME’YE GÖRE TAHLİLİ

OpenAIRE

KOÇ KONUKSEVER, SERPİL

2016-01-01

Firdevsî’nin kaleme aldığı “Şehnâme” İran’ın zengin ve köklü millî değerlerinin bir arada toplandığı destansı bir eserdir. Uzun asırlardan günümüze ulaşan bu eser, hâlâ değerini koruyan dünyanın seçkin epopeleri arasındadır. İranlıların uzun asırlar münasebet içerisinde oldukları Türk, Yunan, Arap ve Çin gibi milletlere ait izleri taşımaktadır. Yazımızda, Şehnâme’de yer alan Çin’e ait imge ve motiflerin tahliline yönelik kavramlar ele alınacaktır...

Role of β1 integrins and bacterial adhesins for Yop injection into leukocytes in Yersinia enterocolitica systemic mouse infection.

Science.gov (United States)

Deuschle, Eva; Keller, Birgit; Siegfried, Alexandra; Manncke, Birgit; Spaeth, Tanja; Köberle, Martin; Drechsler-Hake, Doreen; Reber, Julia; Böttcher, Ralph T; Autenrieth, Stella E; Autenrieth, Ingo B; Bohn, Erwin; Schütz, Monika

2016-02-01

Injection of Yersinia outer proteins (Yops) into host cells by a type III secretion system is an important immune evasion mechanism of Yersinia enterocolitica (Ye). In this process Ye invasin (Inv) binds directly while Yersinia adhesin A (YadA) binds indirectly via extracellular matrix (ECM) proteins to β1 integrins on host cells. Although leukocytes turned out to be an important target of Yop injection by Ye, it was unclear which Ye adhesins and which leukocyte receptors are required for Yop injection. To explain this, we investigated the role of YadA, Inv and β1 integrins for Yop injection into leukocytes and their impact on the course of systemic Ye infection in mice. Ex vivo infection experiments revealed that adhesion of Ye via Inv or YadA is sufficient to promote Yop injection into leukocytes as revealed by a β-lactamase reporter assay. Serum factors inhibit YadA- but not Inv-mediated Yop injection into B and T cells, shifting YadA-mediated Yop injection in the direction of neutrophils and other myeloid cells. Systemic Ye mouse infection experiments demonstrated that YadA is essential for Ye virulence and Yop injection into leukocytes, while Inv is dispensable for virulence and plays only a transient and minor role for Yop injection in the early phase of infection. Ye infection of mice with β1 integrin-depleted leukocytes demonstrated that β1 integrins are dispensable for YadA-mediated Yop injection into leukocytes, but contribute to Inv-mediated Yop injection. Despite reduced Yop injection into leukocytes, β1 integrin-deficient mice exhibited an increased susceptibility for Ye infection, suggesting an important role of β1 integrins in immune defense against Ye. This study demonstrates that Yop injection into leukocytes by Ye is largely mediated by YadA exploiting, as yet unknown, leukocyte receptors. Copyright © 2015. Published by Elsevier GmbH.

Reasons for not receiving thrombolytic therapy in patients with acute myocardial infarction admitted to Bu-Ali Sina Hospital in Qazvin (2013-14)

OpenAIRE

MM. Daei; M. Karimi Rad; M. Khalaja

2017-01-01

This hospital-based cross-sectional study was conducted in 2013-14 in Qazvin Bu-Ali Sina Hospital. 170 patients with acute myocardial infarction who not receiving thrombolytic therapy entered the study and were analyzed. Medical history, physical examination, twelve lead ECG and cardiac biomarkers were obtained. The mean age of the patients was 63.4±14.4 years (from 19 to 90 years). 110 (64.7%) of the patients were male and 48 (28.2%) were diabetic. 86 (50%) of patients due to late present...

Physical Properties of Superbulky Lanthanide Metallocenes : Synthesis and Extraordinary Luminescence of [Eu-II(Cp-BIG)(2)] (Cp-BIG=(4-nBu-C6H4)(5)-Cyclopentadienyl)

NARCIS (Netherlands)

Harder, Sjoerd; Naglav, Dominik; Ruspic, Christian; Wickleder, Claudia; Adlung, Matthias; Hermes, Wilfried; Eul, Matthias; Poettgen, Rainer; Rego, Daniel B.; Poineau, Frederic; Czerwinski, Kenneth R.; Herber, Rolfe H.; Nowik, Israel

2013-01-01

The superbulky deca-aryleuropocene [Eu(Cp-BIG)(2)], Cp-BIG=(4-nBu-C6H4)(5)-cyclopentadienyl, was prepared by reaction of [Eu(dmat)(2)(thf)(2)], DMAT=2-Me2N--Me3Si-benzyl, with two equivalents of (CpH)-H-BIG. Recrystallizyation from cold hexane gave the product with a surprisingly bright and

TÜRKİYE’DE BASEL I, II ve III KURALLARINA UYUM SÜRECİ

OpenAIRE

Ezgi ASLAN KÜLAHİ; Göksel TİRYAKİ; Ahmet YILMAZ

2013-01-01

TÜRKİYE’DE BASEL I, I VE III KURALLARINA UYUM SÜRECİÖzet: Bu çalışma, Basel Kriterleri çerçevesinde Türk Bankacılık Sektörü’nde yapılan çalışmaları değerlendirerek sektörün Basel Kriterleri’ne uyum sürecinde hangi aşamada olduğunu incelemek amacıyla yapılmıştır. Çalışmada; Türkiye’de Basel I ve II Kriterleri’ne geçiş süreci: Basel I ve II’ye yönelik yapılan hazırlık çalışmaları , Basel Kriterleri’ne uyum kapsamında Türk Bankacılık Mevzuatı’nda yapılan yasal düzenlemeler ve BDDK tarafından ger...

Low dose rate 137Cs Brachytherapy source calibration with farmer type ionisation chamber and specialised fabricated jig in Korle-Bu Teaching Hospital

International Nuclear Information System (INIS)

Opare-Asare, K.

2013-06-01

An important part of a general quality assurance (QA) program for brachytherapy dosimetry is the source calibration because wide ranges of uncertainties are quoted by manufactures. This research is aimed at calibrating LDR 137 Cs brachytherapy source in the Korle-Bu Teaching Hospital by multiple-distance air kerma measurement technique using a specialized designed jig and a calibrated therapy ionization chamber. Specialized jig was fabricated with source holder positions and ionization chamber positions on the jig. Farmer type ionization chamber of volume 0.6cm 3 was used with and without build up cap. The results were validated using well type ionization chamber on channels on 1 and 5 taking into account decay correction. Air Kerma rates were determined at multiple distances between 8cm to 12cm from measured charges recorded by Max 4000 electrometer. The scatter dose relationship described by Ezzell [1992] was used to determine scattered radiation. The analytical method of determining air kerma calibration factor of 137 Cs described by Sharma et.al [2011] was used to determine beam quality correction factor for the 137 Cs. Beam attenuation was determined. Experimental data were compared with manufacturer's quoted source strength for verification. Well type ionization chamber results and experimental results on channel V1 and V5 deviated by 2.39% and 1.58% respectively. Experimental data deviated by 4.73% and 1.24% from theoretical data on channels V1 and V5 respectively. The mean of the experimental data deviated from the theoretical data by ±3.1% and from the well type measurements data by ±1.98%. The well type chamber results compared well with the experimental data. This is an indication that the method used for source calibration is a reliable alternative method of source calibration. The method used in this work has proven to be an efficient way of determining the actual source strength of the LDR brachytherapy 137 Cs source in Korle-Bu Radiotherapy Centre

EDİTÖRLERDEN

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ANADOLU KLİNİĞİ TIP BİLİMLERİ DERGİSİ

2018-06-01

Full Text Available Editörlerden,Anadolu Kliniği Tıp Bilimleri dergimizin 21. cilt, 3. sayısı ile yeniden karşınızdayız.21. cildin bir ve ikinci sayılarının her birinde 11’er adet bilimselyazıyı siz değerli okuyucularımıza ulaştırmıştık. İkinci sayının basımınıtakiben 2 Mayıs 2016 tarihinde, dergimizin ilk basıldığı matbaanın bulunduğuKonya şehrimizde, Selçuk Üniversitesi ev sahipliğinde HayatVakfı Konya Şubesi’nin açılışını ve Anadolu Kliniği Tıp Bilimleri dergimizintanıtım toplantısını Dr. Sare Davutoğlu Hanımefendi’nin teşrifleriylegerçekleştirdik. Dergimizin tanıtımı için önemli olan bu gibi etkinlikleriAnadolu’nun diğer şehirlerinde de sürdürmeyi planlıyoruz.Şu an itibariyle Türkiye Atıf Dizini ve Google Akademik dizinde indekslenendergimiz, aynı zamanda bu sayıyla birlikte uluslararası hakemli dergistatüsüne sahip olmuştur. Bunun yanı sıra 21. cilt birinci ve ikinci sayılardakiyazılar da dahil olmak üzere tüm yazılara DOI numarası atanmışolacaktır. Her yeni sayımızla birlikte sizlere daha kaliteli bir bilimsel dergisunmak amacıyla yoğun çabalarımız devam etmektedir. Bu amaçla dergimizdeyayımlanacak olan yazılarda dil kullanımı ile ilgili aşağıdaki hususlarada dikkat çekmek isteriz:Kayıtsız şartsız geçerli olacak kurallardansa duruma göre esneyebilecekkurallar koymak her zaman daha iyidir.Örneğin, yazarken her sözcük için mutlaka öz Türkçe bir karşılık kullanılmayabilir;zira yaygınlık ve anlaşılırlık da oldukça önemli birer etmendir.Bununla birlikte, iki alternatif de sık kullanılmakta ve kolayca anlaşılabilirise, Türkçe olan yeğlenmelidir; örneğin “faktör” yerine “etmen,” “tercih etmek”yerine “yeğlemek” gibi. Ama bunun istisnaları olabilir, örneğin “hastatercihleri” demenin “hasta yeğlemeleri” gibi tuhaf bir söz etmekten yeğoluşu gibi.Anadolu Kliniği’ne gönderilecek yaz

Effects of Supported ( n BuCp) 2 ZrCl 2 Catalyst Active-Center Distribution on Ethylene–1-Hexene Copolymer Backbone Heterogeneity and Thermal Behaviors

KAUST Repository

Atiqullah, Muhammad

2013-07-10

Two catalysts, denoted as catalyst 1 [silica/MAO/(nBuCp) 2ZrCl2] and catalyst 2 [silica/nBuSnCl 3/MAO/(nBuCp)2ZrCl2] were synthesized and subsequently used to prepare, without separate feeding of methylaluminoxane (MAO), ethylene homopolymer 1 and homopolymer 2, respectively, and ethylene-1-hexene copolymer 1 and copolymer 2, respectively. Gel permeation chromatography (GPC), Crystaf, differential scanning calorimetry (DSC) [conventional and successive self-nucleation and annealing (SSA)], and 13C nuclear magnetic resonance (NMR) polymer characterization results were used, as appropriate, to model the catalyst active-center distribution, ethylene sequence (equilibrium crystal) distribution, and lamellar thickness distribution (both continuous and discrete). Five different types of active centers were predicted in each catalyst, as corroborated by the SSA experiments and complemented by an extended X-ray absorption fine structure (EXAFS) report published in the literature. 13C NMR spectroscopy also supported this active-center multiplicity. Models combined with experiments effectively illustrated how and why the active-center distribution and the variance in the design of the supported MAO anion, having different electronic and steric effects and coordination environments, influence the concerned copolymerization mechanism and polymer properties, including inter- and intrachain compositional heterogeneity and thermal behaviors. Copolymerization occurred according to the first-order Markovian terminal model, producing fairly random copolymers with minor skewedness toward blocky character. For each copolymer, the theoretical most probable ethylene sequences, nE MPDSC-GT and n E MPNMR-Flory, as well as the weight-average lamellar thicknesses, Lwav DSC-GT and Lwav SSA DSC, were found to be comparable. To the best of our knowledge, such a match has not previously been reported. The percentage crystallinities of the homo- and copolymers increased linearly as a function of

THE SECOND NEW AND THE PROBLEM OF MEANING IN THE FRAMEWORK OF BEHÇET NECATIGIL’S POEM “WALKING TWO HEAD” “İKİ BAŞINA YÜRÜMEK” ÇERÇEVESİNDE BEHÇET NECATİGİL ŞİİRİNDE İKİNCİ YENİ ETKİSİ VE ANLAM SORUNU

Directory of Open Access Journals (Sweden)

Mehmet YILMAZ

2010-07-01

Full Text Available Behcet Necatigil mainly used the language of everyday speech in his poems of his early period. His poems of his late period does not encompass story elements so he developed a poetry based on a closed meaning language. In this respect, it is possible to observe many elements such as reminding the Second New movement. In this study, in regard to his poem “Walking Two Head”, it has been tried to determine the similarities to the Second New movement in the poems of his late period. Behçet Necatigil, ilk dönem şiirlerinde ağırlıklı olarak günlük konuşma dilini kullanmıştır. Son dönem şiirlerinde hikâye unsurunu ortadan kaldırmış, kapalı anlama dayalı bir şiir dili geliştirmiştir. Bu yönüyle Necatigil’in son dönem şiirlerinde İkinci Yeni’yi anımsatan birçok unsur görmek mümkündür. Bu çalışmada, “İki Başına Yürümek” şiirinden hareketle, Necatigil’in son dönem şiirlerinde İkinci Yeni ile benzerlik gösteren yönler tespit edilmeye çalışılmıştır.

Angļu valodas studentu tematiska vārdu krājuma bagātināšana ar datortehnoloģijas rīku palīdzību

OpenAIRE

Samčuka, Jeļena

2012-01-01

Maģistra darba mērķis bija izpētīt, vai ir iespējams uzlabot konkrētu vārdu apguvi, mācību procesā izmantojot datorprogrammu Quizlet. Pētījuma mērķa sasniegšanai tika aplūkotas teorijas par vārdu krājuma apguvi, tika izpētīta leksikas mācīšanās attīstība, kā arī dažādas pieejas, tai skaitā datorizētā apmācība vārdu krājuma apguvē. Tāpat tika analizēta arī pētnieku attieksme pret datora lietošanu leksikas apguves mācību procesā, kā arī datora izmantošanas priekšrocības un trūkumi. Lai stimulēt...

Yield efficiency for nine apple cultivars grafted on two rootstocks

Directory of Open Access Journals (Sweden)

João Caetano Fioravanço

Full Text Available ABSTRACT: Currently, using smaller trees is one of the most important trends in apple cultivation. It is expected that reduced size plants produce lower amount of fruit, but with high yield and yield efficiency. The aim of this study was to evaluate the yield efficiency (YE of nine apple tree cultivars, grafted on two rootstocks, from the second to the seventh year after planting. The YE indexes oscillated from one to the other year, regardless of rootstock. Correlations between YE and yield per tree and between YE and trunk cross sectional area (TCSA confirmed that efficiency can be increased by the production increment or by the plant's vigor reduction. The usefulness of cumulative YE (ƩYE is highlighted to compare apple tree cultivars after the third year of production. The highest ƩYE indexes were observed for 'Royal Gala' and 'Baigent', on M-9 rootstock, and for 'Gala Real' and 'Maxi-Gala', on Marubakaido/M-9 rootstock.

Atmospheric pressure chemical vapour deposition of vanadium arsenide thin films via the reaction of VCl4 or VOCl3 with tBuAsH2

International Nuclear Information System (INIS)

Thomas, Tegan; Blackman, Christopher S.; Parkin, Ivan P.; Carmalt, Claire J.

2013-01-01

Thin films of vanadium arsenide were deposited via the dual-source atmospheric pressure chemical vapour deposition reactions of VCl 4 or VOCl 3 with t BuAsH 2 . Using the vanadium precursor VCl 4 , films were deposited at substrate temperatures of 550–600 °C, which were black-gold in appearance and were found to be metal-rich with high levels of chlorine incorporation. The use of VOCl 3 as the vanadium source resulted in films being deposited between 450 and 600 °C and, unlike when using VCl 4 , were silver in appearance. The films deposited using VOCl 3 demonstrated vanadium to arsenic ratios close to 1:1, and negligible chlorine incorporation. Films deposited using either vanadium precursor were identified as VAs using powder X-ray diffraction and possessed borderline metallic/semiconductor resistivities. - Highlights: • Formation of VAs films via atmospheric pressure chemical vapour deposition. • Films formed using VCl 4 or VOCl 3 and t BuAsH 2 . • Powder X-ray diffraction showed that crystalline VAs films were deposited. • Films from VOCl 3 had a V:As ratio close to 1 with negligible Cl incorporation. • Films were silver and possessed borderline metallic/semiconductor resistivities

Quantitative Study of Porosity and Pore Features in Moldavites by Means of X-ray Micro-CT

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Giovanni Pratesi

2014-04-01

Full Text Available X-ray micro-computer aided tomography (μ-CT, together with optical microscopy and imaging, have been applied to the study of six moldavite samples. These techniques enabled a complete characterization to be made of the textural features of both Muong Nong-type and common splashform moldavites. A detailed study of the size and distribution of pores or bubbles confirmed the marked variability in pore size among the samples, as well as within each sample, and indicated in the Muong Nong-type moldavites the presence of at least two deformation stages which occurred before and after pore formation.

Application of the kurtosis statistic to the evaluation of the risk of hearing loss in workers exposed to high-level complex noise.

Science.gov (United States)

Zhao, Yi-Ming; Qiu, Wei; Zeng, Lin; Chen, Shan-Song; Cheng, Xiao-Ru; Davis, Robert I; Hamernik, Roger P

2010-08-01

Develop dose-response relations for two groups of industrial workers exposed to Gaussian or non-Gaussian (complex) types of continuous noises and to investigate what role, if any, the kurtosis statistic can play in the evaluation of industrial noise-induced hearing loss (NIHL). Audiometric and noise exposure data were acquired on a population (N = 195) of screened workers from a textile manufacturing plant and a metal fabrication facility located in Henan province of China. Thirty-two of the subjects were exposed to non-Gaussian (non-G) noise and 163 were exposed to a Gaussian (G) continuous noise. Each subject was given a general physical and an otologic examination. Hearing threshold levels (0.5-8.0 kHz) were age adjusted (ISI-1999) and the prevalence of NIHL at 3, 4, or 6 kHz was determined. The kurtosis metric, which is sensitive to the peak and temporal characteristics of a noise, was introduced into the calculation of the cumulative noise exposure metric. Using the prevalence of hearing loss and the cumulative noise exposure metric, a dose-response relation for the G and non-G noise-exposed groups was constructed. An analysis of the noise environments in the two plants showed that the noise exposures in the textile plant were of a Gaussian type with an Leq(A)8hr that varied from 96 to 105 dB whereas the exposures in the metal fabrication facility with an Leq(A)8hr = 95 dB were of a non-G type containing high levels (up to 125 dB peak SPL) of impact noise. The kurtosis statistic was used to quantify the deviation of the non-G noise environment from the Gaussian. The dose-response relation for the non-G noise-exposed subjects showed a higher prevalence of hearing loss for a comparable cumulative noise exposure than did the G noise-exposed subjects. By introducing the kurtosis variable into the temporal component of the cumulative noise exposure calculation, the two dose-response curves could be made to overlap, essentially yielding an equivalent noise

Multilocular Hepatic Abscess Formation and Sepsis due to Yersinia enterocolitica in a Patient with Hereditary Hemochromatosis and Type 2 Diabetes Mellitus

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Matthias Sauter

2017-11-01

Full Text Available Infection with Yersinia enterocolitica (YE typically presents with mild gastroenteritis without systemic infection. However, systemic YE infection has been described in states of iron overload. We present the case of a patient with sepsis with hepatic abscesses due to YE infection. Workup revealed a past diagnosis of diabetes mellitus and hemochromatosis which had been untreated for the previous 5 years due to patient refusal. This case highlights risk factors for systemic infection with YE. A high degree of suspicion for YE infection is warranted in patients with iron overload, diabetes mellitus, or immunosuppression.

Upper gastrointestinal endoscopy at the korle bu teaching hospital, accra, ghana.

Science.gov (United States)

Aduful, Hk; Naaeder, Sb; Darko, R; Baako, Bn; Clegg-Lamptey, Jna; Nkrumah, Kn; Adu-Aryee, Na; Kyere, M

2007-03-01

To study the indications for endoscopy, the endoscopic diagnosis and other lessons learnt. A retrospective and prospective audit of all upper gastrointestinal endoscopies performed in the Endoscopy Unit of the Korle-Bu Teaching Hospital from January 1995 to December 2002 was performed. A total of 6977 patients, 3777 males and 3200 females with age range 1 year 8 months to 93 years were endoscoped. The mean age of males was 43.5 +/- 0.5 and females 43.7 +/- 0.6 years. Epigastric pain (42.5%), dyspepsia (32.8%) and haematemesis and melaena (14.2%) were the commonest reasons for endoscopy. Chronic duodenal ulcer (19.6%), acute gastritis (12.7%), duodenitis (10.2%), oesophagitis (7.5%) were the commonest diagnoses. Normal endoscopy was reported in 41.1% patients, and was higher in the younger age group compared to the older (R = 0.973, P<0.001). Nine hundred and ninety (14.2%) patients were endoscoped for haematemesis and melaena of which chronic duodenal ulcer (32.1%), gastritis/gastric erosions (12.8%), oesophageal varices (9.8%), carcinoma of the stomach (6.4%), and duodenitis (4.2%), were the commonest causes. No lesion was found in 20.6% of these patients. Urease test was positive in 75% of all biopsy specimen and 85% in chronic duodenal ulcer, gastritis and duodenitis. The normal endoscopy rate is high and needs to be reduced in order to help prolong the lives of the endoscopes. Chronic duodenal ulcer is usually associated with H. pylori infection and is the commonest cause of upper gastrointestinal bleeding.

TÜRKİYE MUHASEBE STANDARTLARI VE MÜŞTERİ SADAKATİ PROGRAMLARI KAPSAMINDA VERİLEN PROMOSYON ÜRÜNLERİNİN MUHASEBE UYGULAMASI

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Engin YARBAŞI

2012-11-01

Full Text Available TURKISH ACCOUNTING STANDARDS AND ACCOUNTING APPLICATION OF THE PROMOTIONAL PRODUCTS BASED ON CUSTOMER LOYALTY PROGRAMSAbstract: It is an undeniable and inevitable fact that the world economic growth relies heavily on ever-expanding concept of globalisation. The survival of commercial enterprises, as the most important economic units in this system, directly depends on keeping and broadening their market shares.In the competitive atmosphere that started in the middle of the last century, the concept called Marketing Mix, the 4 P’s, became a part of the literature in 1960’s in order to help the economic units and corporations to maintain their survival. The elements of Marketing Mix- product, place, price and promotion, are instruments developed to lure new customers as well as keep the former loyal ones.  The concept of Promotion evolved greatly in time and companies developed innovative ways to persuade new customers and keep the loyal ones. It was later discovered that the cost of luring new customers is six times more pricy than keeping old ones thus investing in the loyal customers proved to be more attractive. Time difference of the activities of Promotion, the effort of sustaining customer loyalty or commitment of the old buyers, was influential on accounting as well and thus was included in IAS.  Keywords:                Marketing Mix, Turkish Financial Reporting Standards, IFRIC 13.  TÜRKİYE MUHASEBE STANDARTLARI VE MÜŞTERİ SADAKATİ PROGRAMLARI KAPSAMINDA VERİLEN PROMOSYON ÜRÜNLERİNİN MUHASEBE UYGULAMASIÖzet: Dünya ekonomisinin küreselleşme olgusu çerçevesinde gittikçe artan bir hızla gelişmekte olduğu yadsınamaz ve kaçınılamaz bir gerçektir. Bu düzende yer alan en önemli ekonomik birimler olan ticari işletmelerin ömürleri pazar paylarını koruyabilmelerine ve genişletebilmelerine doğrudan bağlıdır.Geçtiğimiz yüzyılın ortalarında başlayan rekabet ortamında ticari

Izlases dizainu salīdzināšana ar simulācijas eksperimentu palīdzību

OpenAIRE

Rikačova, Tatjana

2012-01-01

Darbā tika aplūkoti trīs veidu izlases dizaini: vienkāršā gadījuma izlase, sistemātiskā gadījuma izlase un stratificētā gadījuma izlase, kā arī tika apskatīta GREG novērtējumu teorija. Pētījuma mērķis bija ar simulācijas eksperimentu palīdzību salīdzināt iepriekš minētos izlases dizainus, lai noteiktu izlases dizainu, kas dod precīzākus konkrētās populācijas parametru novērtējumus. Lai veiktu simulācijas eksperimentus tika ģenerēti dati un uzrakstītas programmas, kas tika palaistas va...

Saskarsmes prasmju veicināšana ar mūzikas palīdzību pirmsskolā

OpenAIRE

Gūtšmite, Sana

2017-01-01

Bakalaura darba autore ir Sana Gūtšmite. Bakalaura darba nosaukums: „Saskarsmes prasmju veicināšana ar mūzikas palīdzību pirmsskolā”. Darba mērķis: – teorētiski un empīriski pētīt bērnu saskarsmes prasmju veicināšanas iespējas muzikālās rotaļās un muzikāli ritmiskās kustībās. Darbā izvirzīta sekojoša hipotēze: – pirmsskolas vecuma bērnu saskarsmes prasmes veicināšana būs sekmīgāka, ja pedagoģiskajā procesā skolotājs •izmantos muzikālas rotaļas un muzikāli ritmiskās kustības; •veidos labvēlīg...

Ebu’l Hasan Harakânî’ye Göre Sûfi Benlik Dönüşümü

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ibrahim Işıtan

2013-03-01

ğer bir takım yöntemler ortaya konmuştur. Sûfî anlayış da kendine has metotlarla bir benlik gelişimi teorisi oluşturmuş, seyri sülûk diye adlandırılan rûhî gelişimin temel karakteristiklerini ortaya koymuştur. Modern psikoloji insanın davranışını ve davranışlarındaki patolojik durumları anlamaya ve yeniden düzenlemek için terapi yöntemleri geliştirmeye çalışırken, sûfî hayat biçimi de insanı anlamaya ve olumsuz ve patolojik diye nitelendirebileceğimiz davranışlarını – tasavvuf diliyle ifade edersek nefsin ayıplarını – rûhî ve mânevi yapıya göre yeniden düzene koyma konusu üzerine durmuştur. Bu çalışmada, sûfî benlik dönüşümü konusu, klasik dönemin ünlü sûfilerinden olan Ebu’l Hasan Harakânî’ye göre incelenmiş ve sûfî benlik dönüşümün fizyolojik ve psiko-ruhsal boyutlardaki yansımaları kısaca ele alınmıştır.La Transmutation de Soi selon Ebu’l-Hasan al-HarakânîRésuméLa psychologie soufie est un nouveau domaine de recherche qui étudie les attitudes et comportements des soufis. En parallèle du développement de la psychologie moderne qui étudie les attitudes et comportements humains et leurs origines dans l’organisme de l’homme, on a eu l’occasion d’étudier les attitudes et comportements des soufis selon le point de vue psychologique. En psychologie moderne, on a étudié le sujet de l’intégrité de soi appelé par l’expression de ‘réalisation de soi’ en examinant les principales caractéristiques des personnes dites ‘perfectionnées’ et on a développé certaines méthodes et théories au sujet du développement de la personnalité. La vie soufie a développé une théorie de la personnalité selon ses propres méthodes en étudiant les caractéristiques de base de l’évolution spirituelle de l’homme. La psychologie moderne examine aussi les comportements pathologiques et développe des thérapies adéquates pour réadapter les comportements

The anti-hyperplasia, anti-oxidative and anti-inflammatory properties of Qing Ye Dan and swertiamarin in testosterone-induced benign prostatic hyperplasia in rats.

Science.gov (United States)

Wu, Xinying; Gu, Ye; Li, Lun

2017-01-04

Qing Ye Dan (QYD) is the whole plant of Swertia mileensis and used in Chinese folk medicine for the treatment of prostatitis, benign prostatic hyperplasia (BPH) and so on. This study was to investigate the effects of QYD and its main component swertiamarin on BPH induced by testosterone in rats. The prostatic expressions of vascular endothelial growth factor (VEGF), epidermal growth factor (EGF), basic fibroblast growth factor (βFGF) and proliferating cell nuclear antigen (PCNA) were detected by immunohistochemistry assay. Prostatic levels of oxidative stress and inflammatory-related factors were also analyzed. Additionally, the prostatic expressions of androgen receptor (AR), estrogen receptor (ER)-α, ER-β, hypoxia-inducible factor (HIF)-1α, B-cell CLL/lymphoma (Bcl)-2 and Bcl-2-associated X protein (Bax) were measured by western blot. The epithelial-mesenchymal transition (EMT) associated factors were evaluated by quantitative RT-PCR. It showed that QYD and swertiamarin ameliorated the testosterone-induced prostatic hyperplasia and collagen deposition, attenuated the over-expressions of HIF-1α, VEGF, EGF, βFGF, PCNA, AR and ER-α, reduced the ratio of Bcl-2/Bax, enhanced the expression of ER-β, inhibited the oxidative stress and local inflammation, as well as relieved prostatic EMT. It suggested that QYD and swertiamarin had prostatic protective potential against BPH. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Main aspects in licensing of a type B(U) package design for the transport of 12.95 PBq of cobalt 60; Aspectos relevantes del licenciamiento en Argentina de un modelo de bulto tipo B(U) para transporte de 12,95 PBq de cobalto 60

Energy Technology Data Exchange (ETDEWEB)

Lopez Vietri, J R; Novo, R G; Bianchi, A J

1996-12-31

This paper points out the relevant technical issues related to the licensing process, of a type B(U) package design, with cylindrical form and 9.3 ton mass, approved by the Argentine Competent Authority for the transport of 12.95 PBq of cobalt 60 as special form radioactive material. It is briefly described the heat transfer analysis, the structural performance under impulsive loads and the shielding calculation under both normal and accidental conditions of transport, as well as the comparative analysis of the results obtained from design, pre-operational tests and independent evaluation performed by the Argentine Competent Authority to verify the compliance with the Regulations for the Safe Transport of Radioactive Material of the International Atomic Energy Agency. (author). 14 refs., 1 fig., tabs.

Too early to dismiss Yersinia enterocolitica infection in the aetiology of Graves' disease

DEFF Research Database (Denmark)

Brix, Thomas H; Hansen, Pia S; Hegedüs, Laszlo

2008-01-01

BACKGROUND: Yersinia enterocolitica (YE) infection has long been implicated in the pathogenesis of Graves' disease (GD). The association between YE and GD could, however, also be due to common genetic or environmental factors affecting the development of both YE infection and GD. This potential...

„Unsere tägliche Sendung von der Banalität des Bösen“. Der postmoderne Konflikt in Elfriede Jelineks und Luis Buñuels Würgeengel

Directory of Open Access Journals (Sweden)

Aline Vennemann

2011-12-01

Full Text Available Civilité et barbarie vont de pair. C’est ce que nous suggèrent le cinéaste espagnol Luis Buñuel et la dramaturge autrichienne Elfriede Jelinek dans leurs versions postmodernes de l’Ange exterminateur. En se réclamant de l’allégorie biblique de l’ange mortifère (Todesengel, ils esquissent une société en rupture avec la conception traditionnelle. Ce portrait d’une société que l’on pourrait qualifier de « post-civilisée » invite à repenser, à partir des deux œuvres fictionnelles, le conflit social qui résulte d’une remise en question radicale des normes sociales de l’Occident.Zivilisiertheit und Barbarei bilden einen gemeinsamen Nexus. Dies suggerieren der spanische Regisseur Luis Buñuel und die österreichische Autorin Elfriede Jelinek in ihren postmodernen Fassungen des Würgeengels. Auf die biblische Figur des Todesengels rekurrierend skizzieren sie eine Gesellschaft, die deutlich mit der traditionellen Selbstauffassung bricht. Das Porträt jener Gesellschaft, die man als „post-zivilisiert“ bezeichnen könnte, lädt dazu ein, den sozialen Konflikt, der sich aus der radikalen Infragestellung der westlichen Gesellschaftsnormen ergibt, anhand der zwei fiktionalen Werke zu überdenken.

The reactivity of phosphagermaallene Tip(t-Bu)Ge=C=PMes* with doubly and triply bonded nitrogen compounds.

Science.gov (United States)

Ghereg, Dumitru; Gornitzka, Heinz; Escudié, Jean; Ladeira, Sonia

2010-11-15

Phosphagermaallene Tip(t-Bu)Ge=C=PMes* (1; Mes* = 2,4,6-tri-tert-butylphenyl, Tip = 2,4,6-triisopropylphenyl) gives, with N-benzylidenemethylamine and pivalonitrile, [2+2] cycloadditions between the Ge=C double bond and the C=N and C≡N unsaturations, leading to the formation of the corresponding four-membered heterocycles 2 and 9. With N-tert-butyl-α-phenylnitrone and benzonitrile oxide, [2+3] cycloadditions occur to form the five-membered ring derivatives 6 and 7. By treatment of 1 with derivatives which possess weak acidic hydrogens in α of the C=N or C≡N multiple bond, two types of reactions were observed: an ene reaction with methyl(benzylideneamino)acetate and a 1,2 addition with acetonitrile to afford azadienyl(germyl)ether (4) and 3-germa-1-phosphapropene (8), respectively. In the case of benzonitrile, phosphagermaallene 1 behaves as a 1,3-dipole, to give, via a cyclic phosphagermacarbene intermediate, the tricyclic derivative 10.

Acceptance testing of Siemens e.cam SPECT system at the Korle-Bu Teaching Hospital

International Nuclear Information System (INIS)

Sosu, K. E.

2006-01-01

Acceptance testing has been performed on the Siemens e.cam Signature Series (Single Head) Single Photon Emission Computed Tomography (SPECT) system; the first of its kind, at the Nuclear Medicine Department, Korle-Bu Teaching Hospital, Accra. The various tests were performed according to NEMA NU 1 (2001) specifications as far as possible. The most important parameters that characterized the performance of the camera, gantry system, patient bed, collimators, computer system and fundamental software were evaluated based on visual inspection techniques. Various measuring instruments, different kinds of phantoms, point and flood sources containing 99m-Tc were also used for quantitative studies. Tests performed were divided into Physical inspection, intrinsic measurements (without collimator), extrinsic measurements (with collimator) and Single Photon Emission Computed Tomography (SPECT) system measurement. Some results obtained were better than factory specifications, others were within specifications. Other results obtained from this study which did not have factory specifications for comparison can serve as baseline for future measurements and quality control. Although not all the tests originally planned for could be done due to the non-availability of certain phantoms and radionuclide, it had been possible to perform sufficient and relevant tests to ensure that the system had no serious problems and that it can be used for clinical nuclear medicine imaging. (au)

TÜRKİYE ÇİNGENELERİNİN POLİTİKLEŞMESİ VE ÖRGÜTLENME DENEYİMLERİ - THE POLITICIZATION OF THE GYPSIES IN TURKEY AND THEIR ORGANIZATION EXPERIMENTS

Directory of Open Access Journals (Sweden)

Başak AKGÜL

2012-11-01

Full Text Available Özet:Türkiye’de Avrupa Birliği’ne uyum sürecindegerçekleştirilen reformlarla birlikte, örgütlenme özgürlüğününyasal alanı genişlemiş ve farklı kimliklere yeni ifade alanlarıaçılmıştır. Gerek bu sürecin bir ürünü olarak gündeme gelenimkanlar, gerekse kentsel dönüşüm projeleriyle beraberÇingenelerin yaşam alanının daralması, Çingene kimliğietrafında şekillenen bir örgütlenmeyi teşvik etmiştir. Buçalışmada, Türkiye’de yerel dernekler üzerinden gerçekleşenÇingene örgütlenmesinin genel seyri incelenmektedir. Bubağlamda, Avrupa’daki Çingene örgütlerinin genel eğilimininÇingeneleri etnik bir grup olarak değerlendirmek yönündeolduğu ve bir azınlık kimliğine atıf yaptığı, Türkiye Çingeneörgütlerinin ise topluluğu “Türk ulusunun bir parçası” olaraktanımladığı ve bu çerçevede ulusal vatandaşlık haklarınıntalebi ekseninde şekillenen bir duruş ortaya koyduğu iddiaedilmektedir.Abstract:Due to the reforms which were implemented inTurkey during the integration period with the EuropeanUnion, the legal sphere of the freedom of association wasextended and the representation of various identities wereenabled. The organizations that are based on Gypsy identityare one of the results of this process. Furthermore, therestriction of the Gypsies’ living space as a consequence ofurban transformation projects was one of the dynamics thatfostered their organization. In this study, the general story ofthe Gypsy organization in Turkey which was performedthrough the local associations is scrutinized. In this regard, itis asserted that, the Gypsy organizations in Europe evaluatethe Gypsies as an ethnic group and refer to a minority identity;whereas the Gypsy organizations in Turkey consider thecommunity as “a constituent of Turkish nation” and take aposition which is shaped within the framework of nationalcitizenship rights.

Em torno de Michel Foucault e Luis Buñuel: saber e poder na análise de O Discreto Charme da Burguesia

OpenAIRE

Priscila Canova Motta

2014-01-01

O objetivo desta pesquisa é analisar o filme O Discreto Charme da Burguesia, de Luis Buñuel (1972), por meio de alguns conceitos do referencial teórico-metodológico de Michel Foucault: saber e enunciado discursivo em suas relações com o poder e verdade, e buscar compreender o poder em seu exercício no filme, e não apenas em seus efeitos. Partindo de alguns princípios sobre saber em Foucault, mapeamos um enunciado fílmico que apareceu em algumas sequências, qual seja: O barulho que oculta a di...

Organotin(IV Derivatives of 2-Acetylpyridine-N(4-Phenylthiosemicarbazone, HAP4P, and 2-Hydroxyacetophenone-N(4-Phenylthiosemicarbazone, H2DAP4P: Crystal and Molecular Structure of [SnMe2(DAP4P] and [SnBu2(DAP4P

Directory of Open Access Journals (Sweden)

Sousa Gerimário F. de

2001-01-01

Full Text Available The reactions of 2-acetylpyridine-N(4-phenylthiosemicarbazone, HAP4P, and 2-hydroxyacetophenone-N(4-phenylthiosemicarbazone, H2DAP4P, with R4-mSnXm (m = 2, 3; R = Me, nBu, Ph and X = Cl, Br led to the formation of hexa- and penta-coordinated organotin(IV complexes, which were studied by microanalysis, IR, ¹H-NMR and Mössbauer spectroscopies. The molecular structures of [SnMe2(DAP4P] and [Sn nBu2(DAP4P] were determined by single-crystal X-ray diffraction studies. In the compounds [SnClMe2(AP4P] and [SnBrMe2(AP4P], the deprotonated ligand AP4P- is N,N,S-bonded to the Sn(IV atoms, which exhibit strongly distorted octahedral coordination. The structures of [SnMe2(DAP4P] and [Sn nBu2(DAP4P] revealed that the DAP4P2- anion acts as a O,N,S-tridentate ligand. In these cases, the Sn(IV atoms adopt a strongly distorted trigonal bipyramidal configuration where the azomethine N and the two C atoms are on the equatorial plane while the O and the S atoms occupy the axial positions.

Fractionation of yeast extract by nanofiltration process to assess key compounds involved in CHO cell culture improvement.

Science.gov (United States)

Mosser, Mathilde; Kapel, Romain; Chevalot, Isabelle; Olmos, Eric; Marc, Ivan; Marc, Annie; Oriol, Eric

2015-01-01

Yeast extract (YE) is known to greatly enhance mammalian cell culture performances, but its undefined composition decreases process reliability. Accordingly, in the present study, the nature of YE compounds involved in the improvement of recombinant CHO cell growth and IgG production was investigated. First, the benefits of YE were verified, revealing that it increased maximal concentrations of viable cells and IgG up to 73 and 60%, respectively compared to a reference culture. Then, the analyses of YE composition highlighted the presence of molecules such as amino acids, vitamins, salts, nucleobase, and glucose that were contained in reference medium, while others including peptides, trehalose, polysaccharides, and nucleic acids were not. Consequently, YE was fractionated by a nanofiltration process to deeper evaluate its effects on CHO cell cultures. The YE molecules already contained in reference medium were mainly isolated in the permeate fraction together with trehalose and short peptides, while other molecules were concentrated in the retentate. Permeate, which was free of macromolecules, exhibited a similar positive effect than raw YE on maximal concentrations. Additional studies on cell energetic metabolism underlined that dipeptides and tripeptides in permeate were used as an efficient source of nitrogenous substrates. © 2015 American Institute of Chemical Engineers.

Leaf curl diseases of two solanaceous species in Southwest Arabia are caused by a monopartite begomovirus evolutionarily most closely related to a species from the Nile Basin and unique suite of betasatellites

KAUST Repository

Idris, Ali

2012-10-01

The complete genome of 2780 bases was amplified using rolling circle amplification, and cloned, and sequenced for two distinct strains of the monopartite begomovirus Tomato leaf curl Sudan virus (ToLCSDV). The two strains shared 86-91% identity with the previously described ToLCSDV from the Nile Basin, and 90-91% identity with one another. One strain was cloned from symptomatic tomato plants from Tihamah (ToLCSDV-YE[YE:Tih:05]) while the other was cloned from symptomatic tobacco plants collected from Wadi Hadramaut (ToLCSDV-YE[YE:Had:89]). A distinct full-length betasatellite molecule (1352 bases) was cloned from the respective field-infected tomato and tobacco plants. Agro-inoculation of tomato and Nicotiana benthamiana plants with cloned partial tandem repeats of ToLCSDV-YE[YE:Tih11:05]) and the associated betasatellite, Tomato leaf curl Yemen betasatellite (ToLCYEB-[Tih:tom:137:05]), resulted in the reproduction of leaf curl disease symptoms in test plants like those observed in the field-infected plants. The betasatellite contributed to symptom severity in N. benthamiana test plants when it was co-inoculated with ToLCSDV-YE, compared to the milder symptoms that were observed in tobacco plants infected with the helper virus alone. © 2012 Elsevier B.V.

Leaf curl diseases of two solanaceous species in Southwest Arabia are caused by a monopartite begomovirus evolutionarily most closely related to a species from the Nile Basin and unique suite of betasatellites

KAUST Repository

Idris, Ali; Abdullah, N.; Brown, Judith K.

2012-01-01

The complete genome of 2780 bases was amplified using rolling circle amplification, and cloned, and sequenced for two distinct strains of the monopartite begomovirus Tomato leaf curl Sudan virus (ToLCSDV). The two strains shared 86-91% identity with the previously described ToLCSDV from the Nile Basin, and 90-91% identity with one another. One strain was cloned from symptomatic tomato plants from Tihamah (ToLCSDV-YE[YE:Tih:05]) while the other was cloned from symptomatic tobacco plants collected from Wadi Hadramaut (ToLCSDV-YE[YE:Had:89]). A distinct full-length betasatellite molecule (1352 bases) was cloned from the respective field-infected tomato and tobacco plants. Agro-inoculation of tomato and Nicotiana benthamiana plants with cloned partial tandem repeats of ToLCSDV-YE[YE:Tih11:05]) and the associated betasatellite, Tomato leaf curl Yemen betasatellite (ToLCYEB-[Tih:tom:137:05]), resulted in the reproduction of leaf curl disease symptoms in test plants like those observed in the field-infected plants. The betasatellite contributed to symptom severity in N. benthamiana test plants when it was co-inoculated with ToLCSDV-YE, compared to the milder symptoms that were observed in tobacco plants infected with the helper virus alone. © 2012 Elsevier B.V.

The potential role of B-function gene involved in floral development ...

African Journals Online (AJOL)

Camellia changii Ye, a rare and endangered species, has a phenotype that sepals frequently transform into petals. We assumed that this change would cause single C. changii Ye turned double flowers and this was confirmed by the double flowers we found in grafted C. changii Ye. The microstructure of floral organs ...

Augsnes ķīmisko īpašību raksturojums bioloģiski vērtīgajos un daļēji dabiskajos zālājos Vaives pagastā

OpenAIRE

Elksnītis, Daniels

2016-01-01

Bioloģiski vērtīgos un daļēji dabiskos zālājus būtiski ietekmē augsnes īpašības. No augsnes īpašībām ir atkarīga šo zālāju kvalitāte, apsaimniekošanas veids un līdz ar to arī to sniegtie ekosistēmu pakalpojumi. Bioloģiski vērtīgo un daļēji dabisko zālāju nozīme arvien pieaug, turklāt jau pagājušā gadsimta otrajā pusē sākās strauja to platību samazināšanās gan Latvijā, gan Eiropā kopumā. Tāpēc ir ļoti būtiski noskaidrot bioloģiski vērtīgo zālāju augšņu īpašību ietekmējošos faktorus gan lokālā,...

Kustību pilnveide valodas attīstības traucējumu korekcijā pirmsskolas vecuma bērniem

OpenAIRE

Kampusa, Zane

2012-01-01

Diplomdarbā “Kustību pilnveide valodas attīstības traucējumu korekcijā pirmsskolas vecuma bērniem” autore apskata pirmsskolas vecuma bērnu valodas attīstības īpatnības. Uzmanība tiek vērsta uz sensitīvā valodas attīstības perioda un citu priekšnoteikumu nozīmi bērna valodas sekmīgai attīstībai pirmsskolas vecumā. Diplomdarbā autore sniedz ieskatu, kādi var būt runas un valodas attīstības traucējumu cēloņi un veidi. Tiek raksturotas pirmsskolas vecumposma bērnu attīstības īpatnības, kā arī dot...

Latvijas Komercbanku risku regulēšana un Bāzeles III ieviešanas ietekme uz Komercbanku darbību

OpenAIRE

Kudrjavceva, Anastasija

2013-01-01

Maģistra darba mērķis ir, pamatojoties uz ekonomiskās literatūras un darba autores veikto Latvijas komercbanku risku pārvaldīšanas politiku analīzi, izstrādāt priekšlikumus par Bāzeles III ieviešanu Latvijā, ka arī novērtēt tās ietekmi uz komercbanku darbību. Darbā tiek veikta Latvijas komercbanku risku pārvaldīšanas politiku atbilstības LR likumdošanai un starptautiskiem regulējumiem analīze. Autore izpēta un novērtē komercbanku risku pārvaldīšanas metožu priekšrocības un trūkumus. Tiek i...

Structure-activity relationship of linear peptide Bu-His-DPhe-Arg-Trp-Gly-NH(2) at the human melanocortin-1 and -4 receptors: arginine substitution.

Science.gov (United States)

Cheung, Adrian Wai-Hing; Danho, Waleed; Swistok, Joseph; Qi, Lida; Kurylko, Grazyna; Franco, Lucia; Yagaloff, Keith; Chen, Li

2002-09-02

A series of pentapeptides, based on Bu-His(6)-DPhe(7)-Arg(8)-Trp(9)-Gly(10)-NH(2) and modified at the Arg(8) position, was prepared and pharmacologically characterized. Peptides containing either cyanoguanidine or acylguanidine, two substantially less basic arginine surrogates, were found to retain the agonist activity of the parent peptide at both hMC1R and hMC4R. This study unequivocally shows that the positive charge of Arg(8) is not essential for efficient interactions of our pentapeptide with both hMC1R and hMC4R.

Bronislaw Malinowski’nin Kültür Teorisi

OpenAIRE

Aman, Fatih

2014-01-01

Bir toplumu anlamak o toplumun kültürünü anlamaya bağlıdır. Özellikle “her toplumun kendine özgü olduğu” gerçeği kültür konusunda birçok araştırmanın yapılmasını sağlamış ve kültürel araştırmaları daha da ilginç kılmıştır. Bu araştırmalardan birisi de Bronislaw Malinowski’ye aittir. O, kültürün kökeniyle ilgilenmiş, kültürün fonksiyonlarını tanımlamış, kültürel araştırma tekniklerini ilk defa bilimsel ölçütlerle ortaya koymuş ve eleştirileriyle toplamda bir kültür teorisi oluşturmuştur. Malin...

11

African Journals Online (AJOL)

a routine working week. Special ... day of the working week and retested after finishing work on ... 4. 3. Med. 11,8. 12. -ye. 0. 5. 5. Med. 27,3. 107. -ye. 2. 6. 6. Med. 17,1. 80. -Ye. 0. 7. 3 .... present hours after first exposure (e.g. at night), it is also.

ULUSLARARASI ÇALIŞMA ÖRGÜTÜ (ILO VE ULUSLARARASI SOSYAL GÜVENLİK TEŞKİLATI (ISSA TARAFINDAN YAYINLANAN ULUSLARARASI BELGELERDE SOSYAL GÜVENLİĞİN KAPSAMI VE TÜRKİYE AÇISINDAN DEĞERLENDİRİLMESİ

Directory of Open Access Journals (Sweden)

Cenkhan ALTINTAŞ

2015-02-01

Full Text Available Sosyal güvenlik hakkının, evrensel insan haklarından biri olarak kabul edilmesinden bu yana, sosyal güvenliğin kapsamının genişletilmesine yönelik çabalar giderek artmıştır. Uluslararası boyutlara varan bu çabalar, özellikle düşük gelire sahip bireylerin malullük, yaşlılık, ölüm, analık, hastalık, iş kazası ve meslek hastalığı gibi temel sosyal risklere karşı güvence altına alınması üzerine odaklanmaktadır. Uluslararası Çalışma Örgütü (ILO ve Uluslararası Sosyal Güvenlik Teşkilatı (ISSA, sosyal güvenliğin kapsamının genişletilmesi noktasında uluslararası düzeyde çalışmalar yapmakta ve ortaya koydukları parametrelerle sosyal güvenliğin kapsamına ilişkin olarak uluslararası standartlar geliştirmektedirler. Özellikle sosyal güvenliğin kapsamının sınırlı seviyede olduğu düşük ve orta gelire sahip ülkelerde sosyal güvenliğin kapsamının genişletilmesine yönelik bir takım tavsiyeleri de içeren bu tarz çalışmalar, ülkelerin sosyal güvenliğin kapsamını genişletme girişimlerine yardımcı olmakta ve bir nevi rehber olma niteliği taşımaktadır. Bu bağlamda, çalışmada öncelikle ILO ve ISSA’nın sosyal güvenliğin kapsamına ilişkin olarak uluslararası metinlerle ortaya koydukları kavramlar ve parametrelere yer verilmektedir. Diğer bir başlıkta ise Türkiye’de sosyal güvenliğin kapsamı ILO ve ISSA’nın ortaya koyduğu parametreler çerçevesinde ele alınmaktadır.

New microbial resource: microbial diversity, function and dynamics in Chinese liquor starter.

Science.gov (United States)

Huang, Yuhong; Yi, Zhuolin; Jin, Yanling; Zhao, Yonggui; He, Kaize; Liu, Dayu; Zhao, Dong; He, Hui; Luo, Huibo; Zhang, Wenxue; Fang, Yang; Zhao, Hai

2017-11-06

Traditional Chinese liquor (Baijiu) solid state fermentation technology has lasted for several thousand years. The microbial communities that enrich in liquor starter are important for fermentation. However, the microbial communities are still under-characterized. In this study, 454 pyrosequencing technology was applied to comprehensively analyze the microbial diversity, function and dynamics of two most-consumed liquor starters (Jiang- and Nong-flavor) during production. In total, 315 and 83 bacterial genera and 72 and 47 fungal genera were identified in Jiang- and Nong-flavor liquor starter, respectively. The relatively high diversity was observed when the temperature increased to 70 and 62 °C for Jiang- and Nong-flavor liquor starter, respectively. Some thermophilic fungi have already been isolated. Microbial communities that might contribute to ethanol fermentation, saccharification and flavor development were identified and shown to be core communities in correlation-based network analysis. The predictively functional profile of bacterial communities showed significant difference in energy, carbohydrate and amino acid metabolism and the degradation of aromatic compounds between the two kinds of liquor starters. Here we report these liquor starters as a new functionally microbial resource, which can be used for discovering thermophilic and aerobic enzymes and for food and feed preservation.

Main aspects in licensing of a type B(U) package design for the transport of 12.95 PBq of cobalt 60

International Nuclear Information System (INIS)

Lopez Vietri, J.R.; Novo, R.G.; Bianchi, A.J.

1995-01-01

This paper points out the relevant technical issues related to the licensing process, of a type B(U) package design, with cylindrical form and 9.3 ton mass, approved by the Argentine Competent Authority for the transport of 12.95 PBq of cobalt 60 as special form radioactive material. It is briefly described the heat transfer analysis, the structural performance under impulsive loads and the shielding calculation under both normal and accidental conditions of transport, as well as the comparative analysis of the results obtained from design, pre-operational tests and independent evaluation performed by the Argentine Competent Authority to verify the compliance with the Regulations for the Safe Transport of Radioactive Material of the International Atomic Energy Agency. (author). 14 refs., 1 fig., tabs

Thermophilic biofiltration of benzene and toluene.

Science.gov (United States)

Cho, Kyung-Suk; Yoo, Sun-Kyung; Ryu, Hee Wook

2007-12-01

In the current studies, we characterized the degradation of a hot mixture of benzene and toluene (BT) gases by a thermophilic biofilter using polyurethane as packing material and high-temperature compost as a microbial source. We also examined the effect of supplementing the biofilter with yeast extract (YE). We found that YE substantially enhanced microbial activity in the thermophilic biofilter. The degrading activity of the biofilter supplied with YE was stable during long-term operation (approximately 100 d) without accumulating excess biomass. The maximum elimination capacity (1,650 g x m(-3) h(-1)) in the biofilter supplemented with YE was 3.5 times higher than that in the biofilter without YE (470 g g x m(-3) h(-1)). At similar retention times, the capacity to eliminate BT for the YE-supplemented biofilter was higher than for previously reported mesophilic biofilters. Thus, thermophilic biofiltration can be used to degrade hydrophobic compounds such as a BT mixture. Finally, 16S rDNA polymerase chain reaction-DGGE (PCR-DGGE) fingerprinting revealed that the thermophilic bacteria in the biofilter included Rubrobacter sp. and Mycobacterium sp.

Les conséquences financières de l'épisode pluvieux dans le bassin-versant du Buëch, 1993-1994

Directory of Open Access Journals (Sweden)

Pierre PECH

1994-12-01

Full Text Available Les épisodes pluvio-orageux d’octobre 1993 et de janvier 1994 sont à l’origine de nombreux dommages dans les communes du bassin-versant du Buëch (Hautes-Alpes. La cartographie des phénomènes naturels et de leurs coûts permet de définir une typologie de communes en fonction de l’ampleur de ces dégâts et ces coûts. Les villes et les petites communes rurales montagnardes subissent des charges financières lourdes pour des raisons totalement différentes: dans un cas l’urbanisation est responsable des coûts, dans l’autre c’est la morphologie des versants.

Enhanced coal-dependent methanogenesis coupled with algal biofuels: Potential water recycle and carbon capture

Science.gov (United States)

Barnhart, Elliott P.; Davis, Katherine J.; Varonka, Matthew; Orem, William H.; Cunningham, Alfred B.; Ramsay, Bradley D.; Fields, Matthew W.

2017-01-01

Many coal beds contain microbial communities that can convert coal to natural gas (coalbed methane). Native microorganisms were obtained from Powder River Basin (PRB) coal seams with a diffusive microbial sampler placed downhole and used as an inoculum for enrichments with different nutrients to investigate microbially-enhanced coalbed methane production (MECoM). Coal-dependent methanogenesis more than doubled when yeast extract (YE) and several less complex components (proteins and amino acids) were added to the laboratory microcosms. Stimulated coal-dependent methanogenesis with peptone was 86% of that with YE while glutamate-stimulated activity was 65% of that with YE, and a vitamin mix had only 33% of the YE stimulated activity. For field application of MECoM, there is interest in identifying cost-effective alternatives to YE and other expensive nutrients. In laboratory studies, adding algal extract (AE) with lipids removed stimulated coal-dependent methanogenesis and the activity was 60% of that with YE at 27 d and almost 90% of YE activity at 1406 d. Analysis of British Thermal Unit (BTU) content of coal (a measure of potential energy yield) from long-term incubations indicated > 99.5% of BTU content remained after coalbed methane (CBM) stimulation with either AE or YE. Thus, the coal resource remains largely unchanged following stimulated microbial methane production. Algal CBM stimulation could lead to technologies that utilize coupled biological systems (photosynthesis and methane production) that sustainably enhance CBM production and generate algal biofuels while also sequestering carbon dioxide (CO2).

Eski Türk Edebiyatında Tercüme Geleneği Ve Bu Gelenekte Mantıku’t-Tayr Tercümeleri The Tradition of Translation In Classical Ottoman Literature and Mantıku't- Tayr Translations in This Tradition

Directory of Open Access Journals (Sweden)

Vesile ALBAYRAK SAK

2012-12-01

are less or more, supporting stories are different, main ideasand subjects of these works somehow are fed from the work ofAttar,and the masnawis(poem made up of rhymed coupletshave beensuccessfully worked about being original with the efforts of the poets. Arapça "terceme" kelimesinden tercüme; "çeviri" demek olup ifadelerin bir dilden başka bir dile aktarılmasıdır. Toplumların birbirlerini tanımalarında, ilmî ve fikrî gelişmelerde köprü görevini yerine getirmiş bu faaliyet, kültürler arası etkileşimde önemli rol üstlenmiştir.Medeniyetler bir ülkeden diğerine daha çok tercüme yoluyla girer. Dînî-didaktik edebiyatın önemli bir parçası olan Attar'ın Mantıkut-Tayr'ı da edebiyatımıza tercüme yoluyla girmiştir. Tasavvufî öğretiyi allegorik bir dille, konu bütünlüğü içinde ele alan ve hikâyelerle halka indirgeyen bu eser, kaynak eser olma özelliği kazanmıştır. Mantıku't-Tayr'ın edebiyatımızda XIV. yüzyıldan başlayarak XVIII. yüzyıla kadar her yüzyılda tercümeleri ve benzerleri yazılmıştır.Gülşehrî‟nin Mantıku‟t-Tayr„ı (1317, Ali Şir Nevaî‟nin Lisânü‟t-tayr‟ı (1498/1499, İranlı Şemsî‟nin Deh Murg „u(1514, İbrahim Gülşenî‟nin Sîmurg-nâme‟si (d. 1533, Zaîfî‟nin Gülşen-i Sîmurg‟u (d. 1559, Ârifî Mehmed‟in Ravzatü‟t-Tevhîd‟i (d.1563, Kadıoğlu Şeyh Mehmed'in İnşirâhu‟s-Sadr'ı (1578 ,Şemseddin Sivâsî‟nin Gülşenâbâd‟ı (d. 1595 ve Fedâî Dede‟nin Mantıku‟l- Esrâr‟ı (d.1635 bu eserlerdendir.Bu çalışmada Mantıku‟t-Tayr tercümelerine farklı bir açıdan bakılmış,örneğe bağlı kalanlardan ziyade örnekten ayrılan şairlerin hangi çabalara giriştikleri,esere yeni bir düzen getirme ve eseri farklı açıdan yorumlama uğraşları irdelenmiştir.Örnekten isteyerek ayrılan şairlerin özellikle yardımcı hikâye seçimindeki tasarrufları konuyu dağıtmadan ele almada onlara avantaj sa

THE NARCISSUS STORY WHICH COMPILED FROM ÂŞIK İRFANİ IN THE MALYA MALYA’DA ÂŞIK İRFANİ’DEN DERLENEN NERGİS HİKÂYESİ

Directory of Open Access Journals (Sweden)

Erdoğan ALTINKAYNAK

2011-09-01

Full Text Available The folk stories that constitute a step of literary to novel from epic within types of verbal expression have met many elements that descend from the tradition of mythology, tale and epic since 16th century. Today, the tradition of minstrelsy stil continued tol ive in the Erzurum region depending on the minstresy traditon continues in the tradition of storytelling. In this article, after being mentioned the social background in the tradition of storytelling of Narcissus story which compiled from Âşık İrfani in the Malya, the story has been analyzed in terms of persons, time and place. ÖZET Sözlü anlatım ürünleri içerisinde destandan romana geçişin edebî bir merhalesini teşkil eden halk hikâyeleri, XVI. yüzyıldan itibaren mitoloji, masal ve destancılık geleneğinden miras kalan pek çok unsurla karşımıza çıkmıştır. Günümüzde âşıklık geleneğinin hâlâ canlı olarak devam ettiği Erzurum yöresinde âşıklık geleneğine bağlı olarak hikâye anlatma geleneği de devam etmektedir. Bu makalede, Malya’da Âşık İrfani’den derlenen Nergis hikâyesinin, hikâye anlatma geleneği içerisindeki sosyal zemininden bahsedildikten sonra şahıs kadrosu, zaman ve mekân bakımından tahlili yapılmıştır.

Ekmeklik Buğdayların Kalitelerinin Belirlenmesinde Miksograf Kullanımı Üzerine Araştırmalar

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Ayhan Atlı

2015-02-01

Full Text Available Bu araştırmanın amacı miksograf cihazından elde edilen bulguların diğer kalite kriterleri ile ilişkisini saptamak ve miksografın kalite değerlendirmesinde ne derecede etkili olduğunu belirlemektir. Araştırmada miksograf bulgularının zayıf ve kuvvetli kalitedeki çeşitleri birbirinden ayıracak özellikte olduğu ve çeşitli kalite kriterleri ile önemli düzeyde korelasyon gösterdiği belirlenmiştir. Araştırma sonuçlarına göre, miksograf ile kalite belirlemede en etkili kriterlerin kurve yüksekliği, maksimum konsistens ve alan değerleri olduğu saptanmıştır.

Role of IFN-gamma and IL-6 in a protective immune response to Yersinia enterocolitica in mice

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Autenrieth Ingo B

2008-09-01

Full Text Available Abstract Background Yersinia outer protein (Yop H is a secreted virulence factor of Yersinia enterocolitica (Ye, which inhibits phagocytosis of Ye and contributes to the virulence of Ye in mice. The aim of this study was to address whether and how YopH affects the innate immune response to Ye in mice. Results For this purpose, mice were infected with wild type Ye (pYV+ or a YopH-deficient Ye mutant strain (ΔyopH. CD11b+ cells were isolated from the infected spleen and subjected to gene expression analysis using microarrays. Despite the attenuation of ΔyopH in vivo, by variation of infection doses we were able to achieve conditions that allow comparison of gene expression in pYV+ and ΔyopH infection, using either comparable infection courses or splenic bacterial burden. Gene expression analysis provided evidence that expression levels of several immune response genes, including IFN-γ and IL-6, are high after pYV+ infection but low after sublethal ΔyopH infection. In line with these findings, infection of IFN-γR-/- and IL-6-/- mice with pYV+ or ΔyopH revealed that these cytokines are not necessarily required for control of ΔyopH, but are essential for defense against infection with the more virulent pYV+. Consistently, IFN-γ pretreatment of bone marrow derived macrophages (BMDM strongly enhanced their ability in killing intracellular Ye bacteria. Conclusion In conclusion, this data suggests that IFN-γ-mediated effector mechanisms can partially compensate virulence exerted by YopH. These results shed new light on the protective role of IFN-γ in Ye wild type infections.

A Linear trans-Bis(imido) Neptunium(V) Actinyl Analog: Np(V)(NDipp)2((t)Bu2bipy)2Cl (Dipp = 2,6-(i)Pr2C6H3).

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Brown, Jessie L; Batista, Enrique R; Boncella, James M; Gaunt, Andrew J; Reilly, Sean D; Scott, Brian L; Tomson, Neil C

2015-08-05

The discovery that imido analogs of actinyl dioxo cations can be extended beyond uranium into the transuranic elements is presented. Synthesis of the Np(V) complex, Np(NDipp)2((t)Bu2bipy)2Cl (1), is achieved through treatment of a Np(IV) precursor with a bipyridine coligand and lithium-amide reagent. Complex 1 has been structurally characterized, analyzed by (1)H NMR and UV-vis-NIR spectroscopies, and the electronic structure evaluated by DFT calculations.

THE VILLAGE IN THE STORIES BY YUSUF ATILGAN YUSUF ATILGAN’IN HİKÂYELERİNDE KÖY

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Orhan OĞUZ

2011-09-01

Full Text Available Yusuf Atılgan (1921-1989 collected his stories in a book named “Bodur Minareden Öte” (Beyond the Shortie Minaret (1960. The book consists of three volumes, “Kasabadan” (From the Town “Köyden” (From the Village and “Kentten” (From the City. The space element in four stories of the second volume, -“Tutku”(Passion, “Kümesin Ötesi” (Beyond the Coop, “Dedikodu” (Gossip and “Yük” (Load- has been analyzed in this study. The place of the events, milieu and physical environments of the persons have been dwelled on as parts of the space. İnitially the stories have been analyzed one by one, afterwards an overall evaluation has been done. In the stories by Atılgan the village is a place that an oppressive and narrow milieu and a negative physical environment existed together. The persons of the stories can not achieve their goals. Because of that they long for an escape. Yusuf Atılgan (1921-1989, hikâyelerini “Bodur Minareden Öte” (1960 başlığı altında kitaplaştırmıştır. Kitap, “Kasabadan”, “Köyden” ve “Kentten” başlıklı üç bölümden oluşur. Bu çalışmada kitabın “Köyden” başlıklı ikinci bölümünü oluşturan “Tutku”, “Kümesin Ötesi”, “Dedikodu” ve “Yük” isimli hikâyelerdeki mekân unsuru incelendi. Mekân incelenirken hikâyede olayların geçtiği yer, kişilerin sosyal çevreleri ve fizikî ortamları üzerinde duruldu. Her hikâye ayrı ayrı incelendikten sonra genel bir değerlendirmeye gidildi. Atılgan‟ın hikâyelerinde köy; kişiler için baskıcı ve dar bir sosyal çevrenin olumsuz fizikî şartlarla buluştuğu bir yerdir. Hikâye kişileri rüyalarını gerçekleştirmek bakımından imkânsızlıkla kuşatılmışlardır. Bu sebeple bir kaçışı arzularlar.

ÜÇ MAYMUN, PANDORA’NIN KUTUSU, GÜZEL GÜNLER GÖRECEĞİZ, NAR, GERİYE KALAN, ŞİMDİKİ ZAMAN VE ZERRE FİLM ÖRNEKLERİYLE: TÜRK SİNEMASINDA KENTLİ KADIN OLGUSU

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Gül Yaşartürk Yaşartürk

2015-01-01

Full Text Available Türk sinemasında ilk yıllarından başlamak üzere sınıf farkı, kültür farkı, yaşam biçimi, giyim-kuşam, aile ve cinsiyet rollerinde modern ve geleneksel karşıtlıkları çoğu zaman kent ve taşra ayrımında ortaya konulur. Bu filmlerde çoğu zaman, dürüst, ahlaklı, değerlerine bağlı ve inançlı olmak, namus ve şeref gibi değerler taşra kültürü ile özdeşleştirilirken, modern, Batılı yaşam tarzı, aile, inanç ve değerlerinden uzaklaşmış, ahlaki çöküntü içinde yaşayan, içki ve ihanetin pençesinde kıvranan kentlilere, dolayısıyla kent kültürüne dayatılır. Ancak özellikle 1940’lı yıllardan başlayan ve hızla devam eden taşradan kente göçle birlikte taşra kent, merkez ve periferisi bağlamında kent ve kentli kavramları da değişim ve dönüşüme uğramıştır.  Bu çalışmada günümüz Türk sinemasında kentli kadın olgusunu kadın ve kent ilişkisi bağlamında örnek film analizleriyle ortaya koymayı amaçlamaktadır. Bu amaçla 2000’li yıllardan itibaren Türk sinemasında kentli kadın temsilleri yedi film örneğinde niteliksel içerik analizi yöntemi ile incelenecektir.

Kanegelo ya Nimirode: Re lebelela diphihlelelo t�a gagwe ka lefsa

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Elelwani B. Farisani

2011-03-01

Full Text Available Kanegelo ya Hama/Nimirode e �omi�it�we go gatelela Bathobaso ba Afrika-Borwa le ba Amerika. Taodi�wana ye e lekola Nimirode ka lefsa le go t�ea magato a go bu�et�a seriti sa gagwe le sa Bathobaso sekeng.Seo se tlo dirwa ka dikgato t�e tlhano ka mo tlase. Sa mathomo, re tlo lekola dimelo t�a bana ba Noage, go kwe�i�a Nimirode, yo e lego yena �edi ye kgolo ya taodi�wana ye. Sa bobedi re tlo lebelela ka fao bangwadi ba bangwe ba t�welet�ago seswant�ho sa go befa sa Nimirode. Sa boraro, re tlo sekaseka tiri�o ya kanegelo ya Hama/Nimirode go gatelela le go dira Bathobaso makgoba. Sa bone, re tlo sekaseka diphihlelelo le dikatlego t�a Nimirode. Mo re tlo tsepelela diphihlelelo t�a gagwe t�e tharo t�e kgolo bjalo ka go ba mmu�i wa maemo, motsomi yo maatla le moagi. Nepo ya karolo ye ke go ganet�ana le tshekatsheko ya go se be botse ye e nepilwego Nimirode nakong ya go feta. Re tlo tlalelet�a ka go fa tshekatsheko ye e tebilego ya thogako godimo ga Hama/Ku�e/Nimirode. Sa bohlano, ebile e le sa mafelelo, re tlo t�welet�a nyanyeng bohlokwa bja kanegelo ya Nimirode go bao ba bego ba gatelet�we le go ba makgoba ka baka la temana ye. Re tlo nepi�a Afrika-Borwa.

THE NOTION OF HIGHLAND IN THE POLYES IN AND AROUND MUĞLA IN TERMS OF CULTURAL GEOGRAPHY KÜLTÜREL COĞRAFYA BAKIMINDAN MUĞLA VE ÇEVRE POLYELERDE YAYLACILIK

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Mustafa ERTÜRK

2010-07-01

Full Text Available Bu çalışmada başta Muğla polyesi olmak üzere yakın çevresindeki Ula, Yeşilyurt, Yerkesik, ve Yenice polyelerinde yer alan yayla yerleşmeleri kültürel coğrafya prensipleri çerçevesinde incelenmiştir. Muğla ve çevresi üzerinde karstik şekillerin geliştiği bir plato görünümündedir. Su ve toprak koşullarının kısıtlı olduğu ve yoğun maki örtüsünün geliştiği bu plato üzerinde yerleşmeler daha çok polyeler üzerinde gelişmiştir. Polyelerin kazandırdıkları tarımsal zenginlik, su kaynaklarının varlığı ve çevre fiziki koşullarının rüzgâr yönüne etkisi gibi faktörler, Anadolu yaylacılık anlayışının Muğla çevresinde farklılaşmasına sebep olmuştur. Devamlı yerleşme merkezlerinden daha aşağıda ve genellikle “yayla” denilen bu bahçe içi yerleşmeler, şekil olarak çoğunlukla toplu, çitlerle çevrili bahçeler içinde yapılmış evler ile dar ve dolambaçlı çıkmaz yollu sokaklardan meydana gelir. Yaylalar konutları, kahveleri, mescitleri, yolları, yurtları ve bazılarındaki kent mekânlarıyla farklı kültür mekânları sunarlar. In this study, highlands located mainly in Muğla Polye and nearby areas such as those in Ula, Yeşilyurt, Yerkesik and Yenice have been investigated in the framework of the principles of cultural geography. Muğla and its environs look like a plateau where carstic features have been formed. The settlements have mostly been developed in the polyes on the plateau where there is a shortage of water and arable land and where densely populated bushes are grown. The factors such as agricultural richness that polyes provide, the availability of the water sources, and the effects of the physical conditions on the directions of the wind made common Anatolian concept of highland settlement different in Muğla. The highland settlements which are typical of this area consist of patch of lands or gardens with a small house and bordered with bushes

First-in-man randomised comparison of the BuMA Supreme biodegradable polymer sirolimus-eluting stent versus a durable polymer zotarolimus-eluting coronary stent: the PIONEER trial.

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von Birgelen, Clemens; Asano, Taku; Amoroso, Giovanni; Aminian, Adel; Brugaletta, Salvatore; Vrolix, Mathias; Hernandez-Antolín, Rosana; van de Harst, Pim; Iñiguez, Andres; Janssens, Luc; Smits, Pieter C; Wykrzykowska, Joanna J; Ribeiro, Vasco Gama; Pereira, Hélder; da Silva, Pedro Canas; Piek, Jan J; Onuma, Yoshinobu; Serruys, Patrick W; Sabaté, Manel

2018-04-20

A second iteration of a sirolimus-eluting stent (SES) that has a biodegradable PLGA polymer coating with an electrografting base layer on a thin-strut (80 µm) cobalt-chromium platform (BuMA Supreme; SINOMED, Tianjin, China) has been developed. This first-in-man trial aimed to assess the efficacy and safety of the novel device. This randomised, multicentre, single-blinded, non-inferiority trial compared the BuMA Supreme SES versus a contemporary durable polymer zotarolimus-eluting stent (ZES) in terms of angiographic in-stent late lumen loss (LLL) at nine-month follow-up as the primary endpoint. A total of 170 patients were randomly allocated to treatment with either SES (n=83) or ZES (n=87). At nine-month angiographic follow-up, in-stent LLL was 0.29±0.33 mm in the SES group and 0.14±0.37 mm in the ZES group (pnon-inferiority=0.45). The in-stent percent diameter stenosis and the binary restenosis rate of the two treatment arms were similar (19.2±12.0% vs. 16.1±12.6%, p=0.09, and 3.3% vs. 4.4%, p=1.00, respectively). At 12-month clinical follow-up, there was no difference between treatment arms with regard to the device-oriented composite clinical endpoint (4.9% vs. 5.7%; p=0.72). The PIONEER trial did not meet its primary endpoint in terms of in-stent LLL at nine-month follow-up. However, this result did not translate into any increase in restenosis rate or impairment in 12-month clinical outcomes.

TÜRKİYE-ROMANYA İLİŞKİLERİ(1930-1938 THE RELATIONS OF TURKEY-ROMANIA(1930-1938

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Selman YAŞAR

2012-12-01

şlamıştır. Dış politikada “Yurtta sulh cihanda sulh” prensibini uygulayan Türkiye, devletin kurulduğu ilk yıllarda kendi problemlerini çözmeye çalışmıştır. Türkiye bu dönemde milletlerarası barış çalışmalarında yeralmış, çevresindeki ülkelerle barış antlaşmaları imzalamıştır. Komşularıyla dostça ilişkiler içinde bulunmuş ve dünyadaki problemlerin çözümü için çaba sarfetmiştir. I.Dünya Savaşı sonunda geniş topraklara sahip olan Romanya kendi topraklarını korumak amacıyla anti-revizyonist bir politika izlemiştir. Türkiye’nin de bu politikayı izlemesi iki ülkeyi birbirine yaklaştırmıştır.Lozan Konferansı’na katılan Romanya kapitülasyonlar konusunda Türkiye’yi desteklemiştir. Lozan Antlaşması’ndan sonra Ankara ve Bükreş’te karşılıklı elçilikler açılmıştır. İki ülke arasındaki ilişkiler Avrupa’daki gelişmeler ve Balkan Paktı doğrultusunda gelişmiştir ve iki ülke ilişkileri 1930-1938 yılları arasında dostça sürmüştür. 1930-1938 yılları arasında iki ülke dostluk ve ticaret antlaşmaları imzalamış ve dünyadaki gelişmeler karşısında beraber hareket etmişlerdir. İki ülke Balkanlar’da ve Avrupa’da statükonun korunması için gayret etmişlerdir. Türkiye ile Romanya arasında ilk anlaşma 1929’da yapılmıştır ve 1938’e kadar siyasi ve ekonomik alanda işbirliği yapılmıştır. Bu amaçla karşılıklı ziyaretler gerçekleştirilmiştir. İki ülke arasında dostluk ve ticaret antlaşmaları imzalanmıştır. Romanya Dışişleri Bakanı Titilescu’nun Ankara ziyareti esnasında 17 Ekim 1933’te Türkiye ile Dostluk, Saldırmazlık ve Hakem Antlaşması imzalanmıştır. Türkiye ve Romanya, 9 Şubat 1934’te kurulan Balkan Paktı’nda yer almışlardır. Romanya Montrö Antlaşması’nda Türkiye’yi desteklemiştir.

Monitoring toxic cyanobacteria and cyanotoxins (microcystins and cylindrospermopsins) in four recreational reservoirs (Khon Kaen, Thailand).

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Somdee, Theerasak; Kaewsan, Tunyaluk; Somdee, Anchana

2013-11-01

The toxic cyanobacterial communities of four recreational reservoirs (Bueng Kaen Nakhon, Bueng Thung Sang, Bueng Nong Khot, and Bueng See Than) in Amphur Muang, Khon Kaen Province, Thailand, were investigated. Water samples were collected via monthly sampling from June to October 2011 for the study on the diversity and density of toxic cyanobacteria and toxin quantification. The main toxic cyanobacteria present in these reservoirs were Aphanocapsa sp., Cylindrospermopsis sp., Leptolyngbya sp., Limnothrix sp., Microcystis sp., Oscillatoria sp., Planktolyngbya sp., Planktotrix sp., and Pseudanabaena sp. The dominant bloom-forming genera in the water samples from Bueng Nong Khot and Bueng See Than were Microcystis sp. and Cylindrospermopsis sp., respectively. Enzyme-linked immunosorbent assays specific for cyanotoxins were performed to detect and quantify microcystins and cylindrospermopsins, with the highest average microcystins content (0.913 μgL(-1)) being found in the sample collected from Bueng Nong Khot and the highest average cylindrospermopsins content (0.463 μgL(-1)) being found in the sample collected from Bueng See Than. The application of 16S rRNA analyses to cyanobacterial isolates BKN2, BNK1, BNK2, and BST1 indicated that these isolates are most closely related to Limnothrix planctonica (JQ004026) (98% similarity), Leptolyngbya sp. (FM177494) (99% similarity), Microcystis aeruginosa (DQ887510) (99% similarity), and Limnothrix redekei (FM177493) (99% similarity), respectively.

Analysis of volatiles from irradiated yeast extract

International Nuclear Information System (INIS)

Liao Tao; Li Xin; Zu Xiaoyan; Chen Yuxia; Geng Shengrong

2013-01-01

The method for determination volatiles from irradiated yeast extract (YE) using headspace solid phase microextraction (HS-SPME) and gas chromatography-mass spectrometry (GC-MS) was developed in this paper. The extraction conditions were optimized with reference to the peak area and number of volatiles as aldehyde, ketone, alcohol, acid, ester and sulfur compounds. The optimized conditions of HS-SPME for volatiles in irradiated YE were: divinyl benzene/Carboxen/polydimethylsiloxane (DVB/CAR/PDMS) fiber, extration time 40 min, extraction temperature 40℃. The volatiles from YE irradiated by 0-19.8 kGy were detected using HS-SPME coupled with GC-MS. The results showed that only 15 volatiles were detected from no irradiated YE and main compounds were acetic acid, 2, 3-butanediol and 1-hexanol, 2-ethyl-. There were 40 volatiles detected from irradiated YE and the main compounds were acetic acid, phenylethyl alcohol, heptanal and nonanal. Compare to no irradiated yeast extract, the aldehyde, ketone, alkene and disulfide, dimethyl were produced by irradiating process. (authors)

A de novo designed 11 kDa polypeptide: model for amyloidogenic intrinsically disordered proteins.

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Topilina, Natalya I; Ermolenkov, Vladimir V; Sikirzhytski, Vitali; Higashiya, Seiichiro; Lednev, Igor K; Welch, John T

2010-07-01

A de novo polypeptide GH(6)[(GA)(3)GY(GA)(3)GE](8)GAH(6) (YE8) has a significant number of identical weakly interacting beta-strands with the turns and termini functionalized by charged amino acids to control polypeptide folding and aggregation. YE8 exists in a soluble, disordered form at neutral pH but is responsive to changes in pH and ionic strength. The evolution of YE8 secondary structure has been successfully quantified during all stages of polypeptide fibrillation by deep UV resonance Raman (DUVRR) spectroscopy combined with other morphological, structural, spectral, and tinctorial characterization. The YE8 folding kinetics at pH 3.5 are strongly dependent on polypeptide concentration with a lag phase that can be eliminated by seeding with a solution of folded fibrillar YE8. The lag phase of polypeptide folding is concentration dependent leading to the conclusion that beta-sheet folding of the 11-kDa amyloidogenic polypeptide is completely aggregation driven.

Gestational diabetes mellitus among women attending prenatal care at Korle-Bu Teaching Hospital, Accra, Ghana.

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Oppong, Samuel A; Ntumy, Michael Y; Amoakoh-Coleman, Mary; Ogum-Alangea, Deda; Modey-Amoah, Emefa

2015-12-01

To determine the burden of gestational diabetes mellitus (GDM) among pregnant women in Accra, Ghana. The present cross-sectional study enrolled women at 20-24 weeks of pregnancy attending their first prenatal clinic at Korle-Bu Teaching Hospital, Accra, between March and November 2013. Participants underwent a 2-hour, 75-g oral glucose tolerance test between 24 and 28 weeks. The odds of GDM among different body mass index (BMI, calculated as weight in kilograms divided by the square of height in meters) groupings were calculated in a multiple logistic regression model. Among 399 women screened, 37 (9.3%) had GDM. Compared with women with a BMI in the normal range (18.50-24.99), obese women (BMI >30.0) had an increased risk of GDM (odds ratio [OR] 2.98, 95% confidence interval [CI] 1.08-8.20; P=0.034]; overweight women (BMI 25.00-29.99) had a slightly elevated risk (OR 1.20, 95% CI 0.41-3.55; P=0.742). Maternal age, parity, education, employment status, place of residence, and previous pregnancy complications did not affect the risk of GDM. GDM was found in 10% of pregnant women in Accra. Women who were obese by 20-24 weeks of pregnancy had a significantly increased risk of GDM. Copyright © 2015 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

Portföy Yönetiminde Sistematik Olmayan Riski Azaltacak Bir Doğrusal Programlama Model Önerisi

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Murat UĞURLU

2016-04-01

Full Text Available Geleneksel portföy teorisi portföy riskini azaltmak için çeşitlendirmeye önem verirken modern portföy teorisi geçmiş nicel bilgileri kullanarak matematiksel ve istatistiksel yöntemlerle yatırımcıya etkin sınır üzerinde bir portföy oluşturma seçeneğini sunmaktadır. Modern portföy teorisinin öncülerinden Markowitz risk olarak standart sapmayı dikkate almıştır. Seçim yapılacak hisse senetlerinin sayısının çokluğu standart sapma hesaplamalarını zorlaştırmaktadır. Konno ve Yamazaki risk olarak standart sapma yerine mutlak sapmayı kullanmış, böylelikle portföy seçimi doğrusal programlama modeli olarak ifade edilebilmiştir. Her iki model portföye girecek hisse senetlerinin sayısına ve endüstri kollarına dağıtılmasına müdahale edemez. Bu ise oluşacak portföyün, teorik olarak bir tek hisse senedinden oluşmasını mümkün kılabilir. Bu çalışmada, bahsedilen olumsuzluğu gidermek amacıyla Konno ve Yamazaki modeli ilave kısıtlarla genişletilerek yatırımcıya en yüksek beklenen getiriyi sağlayan yeni bir doğrusal programlama modeli önerisi yapılmaktadır.

HASTA VERİLERİ ÜZERİNDE VERİ MADENCİLİĞİ UYGULAMASI İLE KALP KRİZİ RİSKİNİN TESPİTİ

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İlhan TARIMER

2015-04-01

Full Text Available Bu çalışmada, veri tabanları içerisinde, karar verme süreçlerine etki edebilecek anlamlı bilgileri çıkarmak için kullanılan veri madenciliğinin sağlık alanında uygulanabilirliği araştırılmıştır. Alan çalışmasına örnek olarak, kalp krizi geçiren hastaların kan değerlerinde meydana gelen ortak değişimler tespit edilerek kalp krizini tetikleyen faktörlerin tespitine çalışılmış; elde edilen sonuçlar hasta grubu üzerinde test edilerek yapılan analizin başarımı ölçülmüştür. Bu çalışmada birliktelik kuralı algoritmalarından Apriori ve Gri algoritmaları kullanılmış; bunların oluşturdukları kural kümelerinin başarımı, karşılaştırmalar yapılarak incelenmiştir. Gri algoritmasının Apriori’ye göre daha az kural ürettiği halde aynı başarımı gösterdiği tespit edilmiştir. Sonuç olarak kan değerleri verilen bir hasta grubu verilerinden kalp krizi riskinin tespiti için ön sinyaller anlamına gelen çeşitli desenler ortaya konmuştur

Comparative studies on permanent prostate brachytherapy: pre-plan and real-time transrectal ultrasound guided iodine-125 seed implants at Korle-Bu Teaching Hospital, Ghana

International Nuclear Information System (INIS)

Kalolo, L.T.

2013-06-01

This research was carried out to investigate and compare the real-time and pre-plan implant at the Radiotherapy Department of the Korle Bu Teaching Hospital, Ghana. Prowess Panther 4.5 treatment planning system and variseed 7.2 software were used for pre-plan and real-time implant respectively. The study was conducted for eighty three (83) patients treated for prostate cancer through real-time implant brachytherapy between september, 2008 to April, 2013. Thirty one patients (31) patients whose ultrasound images were available were selected for the pre-plan study. The slices of ultrasound images were re-drawn on transparent A-4 sheets and later on scanned, contoured and registered in the treatment planning system (prowess 4.5). After planning, the volume to be implanted, total number of needles, seeds and the total activity of the source were displayed. Comparison was done withe the pre-plan and real-time implant. In both cases the variation was below 5% as recommended in dosimetry. About 30% - 40% of the imported seeds were left un-used due to over-estimation of seeds ordered from the manufacturer (BARD Company-USA). Hence this work (pre-plan) aims to solve this problem. The comparison for dosimetric parameters was assessed for prostate, urethra and rectum as (V 95%, V 100%, V 150%, D90Gy, D90%), (D90Gy, D90%, D30Gy, D30% ) and (V 100%, D30Gy and D30%) respectively and the variation were within the limit of ± 5%. Comparison of dosimetric values for this work were done with other institutions, like Karolinska university hospital, Sweden, The institute of Curie/ hospital Cochin Group Paris-France and European recommendations. The values reported at Korle - Bu teaching hospital (this work) were in good agreement with the international guidelines. (au)

Mononuclear Amido and Binuclear Imido Zirconium Complexes Supported by Dibenzotetraaza[14]annulene Ligands. X-ray Structure of [(Me(4)taa)Zr(&mgr;-NR)(2)Zr(NHR)(2)] (R = Bu(t) or 2,6-C(6)H(3)Me(2)).

Science.gov (United States)

Nikonov, Georgii I.; Blake, Alexander J.; Mountford, Philip

1997-03-12

Reaction of 2 equiv of Li[NH-2,6-C(6)H(3)R(2)] with [(Me(4)taa)ZrCl(2)] (Me(4)taaH(2) = tetramethyldibenzotetraaza[14]annulene) gives the bis(amido) derivatives [(Me(4)taa)Zr(NH-2,6-C(6)H(3)R(2))(2)] [R = Pr(i) (1) and Me (2)]. Addition of Me(4)taaH(2) to [Zr(N-2,6-C(6)H(3)Pr(i)(2))(NH-2,6-C(6)H(3)Pr(i)(2))(2)(py)(2)] also affords 1. The reaction of 2 equiv of aryl or alkyl amines H(2)NR with the bis(alkyl) complex [(Me(4)taa)Zr(CH(2)SiMe(3))(2)] is the most versatile method for preparing [(Me(4)taa)Zr(NHR)(2)] (R = 2,6-C(6)H(3)Pr(i)(2), 2,6-C(6)H(3)Me(2), Ph, or Bu(t)). Reaction of 1 equiv of Me(4)taaH(2) with the binuclear complexes [(Bu(t)NH)(2)Zr(&mgr;-NBu(t))(2)Zr(NHBu(t))(2)] or [(py)(HN-2,6-C(6)H(3)Me(2))(2)Zr(&mgr;-N-2,6-C(6)H(3)Me(2))(2)Zr(NH-2,6-C(6)H(3)Me(2))(2)(py)] gives the asymmetrically substituted derivatives [(Me(4)taa)Zr(&mgr;-NR)(2)Zr(NHR)(2)] [R = Bu(t) (6) or 2,6-C(6)H(3)Me(2) (8)], which have been crystallographically characterized.

Synthesis, characterization, DFT and Td-dfT study of the [Fe(mnt(L(t-BuNC 2] octahedral complex (L = phen, bipy

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Milton K. MorigakiI

2009-01-01

Full Text Available FeBr2 has reacted with an equivalent of mnt2- (mnt = cis-1,2-dicyanoethylene-1,2-dithiolate and the α-diimine L (L = 1,10'-phenantroline, 2,2'-bipyridine in THF solution, and followed by adding of t-butyl-isocyanide to give [Fe(mnt(L(t-BuNC2] neutral compound. The products were characterized by infrared, UV-visible and Mössbauer spectroscopy, besides thermogravimetric and conductivity data. The geometry in the equilibrium was calculated by the density functional theory and the electronic spectrum by the time-dependent. The experimental and theoretical results in good agreement have defined an octahedral geometry with two isocyanide neighbours. The π→π* intraligand electronic transition was not observed for cis-isomers in the near-IR spectral region.

Effect of enhanced UV-B radiation on yield and quality of rice

International Nuclear Information System (INIS)

Yin Hong; Guo Wei; Mao Xiaoyan

2009-01-01

The effects of enhanced UV-B radiation on yield and quality of two rice cuhivars(ShenNong 6014 and ShenNong 265) are studied in potted method. There were three treatments including natural light (TCK), enhanced 5% UV-B radiation (T) and enhanced 10% (T). The results showed that enhanced UV-B radiation decreases yield components, the percentage of brown rice (0.66%-7.06%), head rice rate (5.65%-18.88%), the rate of white rice (22.17%-40.16%), grain area (2.61%-6.25%), fatty acid contents (1.23%-54.19%) and eating quality (1.07%-16.78%) but increasea protein content (4.65%-10.71%) and amylose content of rice (0.56%-4.81%). The effects of T2 was stronger than T1

Kıbrıs Mülkiyet Tartışmasına Taşınmaz Mal Komisyonu Açısından Bir Bakış Cyprus Property Dispute through the Glance of Immovable Property Commission

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Derya ÖZVERİ

2013-07-01

�erçevesindetanımlamak amaçlanmaktadır. Ardından Kıbrıs’ta Türk ve Yunantarafların mülkiyet tartışmasına bakış açılarını da ele alınacaktır. İkitarafında müzakare masasında çok esneme payı bırakmadıkları bubakış açıları birbirinden çok farklı bir yapı da olması, uzlaşınınoluşabilmesini olanaksızlaştırdığından bu argümanlar daha da önemkazanmaktadır. Anlaşmazlığın taraflardan biri olan Türk tarafi ikibölgelilik,Yunan tarafı ise insan hakları argümanları üzerinden konuyayaklaşmaktadır. Taraflar tezlerini bu yönde savunurken, bu çalışmaAvrupa Insan Haklari Mahkemesi´nin iki önemli karari ile (LoizidouTürkiye´ye Karşı ve Xenides-Arestis Türkiye‘ye Karsi kurulmasinasebebiyet verdiği ve kararları ile bir iç hukuk yontemi olaraktüketilmesini ön-kosul olarak gösterdiği Tasinmaz Mal Komisyonu´nuincelemeye çalışacak ve artık görüşme masasında kemikleşmiş bir konuhaline gelmiş, adanın mülkiyet sorununa yeni bir umut ışığıolabileceğini tartışmayı amaçlamaktadır.

IN RUSSIA THE DICTIONARY COMPILED FROM PUBLIC DIALECT AND ITS CONTRUTION TO TURKOLOGY RUSYA’DA HALK AĞZINDAN DERLEME SÖZLÜĞÜ VE TÜRKOLOJİYE KATKISI

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Muvaffak DURANLI

2009-07-01

Full Text Available The compilation studies carried out at the field occupy a significant place among the language studies as well as on-the-desk works. As in worldwide, Russian compilation studies were carried out in late 1800s sometimes by scientists and sometimes by amateurs by taking small scale regions as a basis. In these small scale compilation studies those words included in dialects spoken in the ragion and not used in the common Russian have drawn Russian scietific circles’ attention. Yet a compiled dictionary work at a scientific level was carried out in 1965. This compilation dictionary we will attempt to introduce is being taken as a primary source in the works by Russian scietists on topics such as dialect features. However, this compilation dictionary has also the quality to be taken as a source by Turkologs since it shows Turkisms prevalent in dialects and how they are used in Russian dialects by undergoing differentiation. Dil çalışmalarında masa başı incelemelerin yanı sıra sahada yapılan derleme çalışmaları da önemli bir yere sahiptir. Bütün dünyada olduğu gibi Rusya’da da derleme çalışmaları 1800’lü yılların sonunda küçük ölçekli bölgeler baz alınarak bazen amatörler bazen de bilim adamları tarafından gerçekleştirilmiştir. Bu küçük ölçekli derleme çalışmalarında bölgede konuşulan ağızlarda yer alan ve ortak Rusça’da kullanılmayan kelimeler Rus bilim çevreleri tarafından ilgiyle karşılanmıştır. Bilimsel düzeyde bir halk ağzından derleme sözlüğü çalışması ise ancak 1965 yılında hayata geçirilmiştir. Tanıtmaya çalışacağımız bu derleme sözlüğü, ağız özellikleri gibi konularda Rus bilim adamlarının çalışmalarında birincil bir kaynak olarak ele alınmaktadır. Fakat aynı zamanda bu derleme sözlüğü ağızlarda yaygın olan Türkizmler ve Türkizmlerin Rusça’nın ağızlarında nasıl değişime uğrayarak kullanıldığını göstermesi a

Erken Cumhuriyet Yılları Milli Kimlik Tartışmaları: Hasan Ali Yücel ve Türkiye’de Hümanizma Arayışları Discussions on National Identity in the Early Republican Years: Hasan Ali Yucel and Searching for Turkish Humanism

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Emre YILDIRIM

2013-09-01

Full Text Available This article aims to demonstrate a small group of intellectuals’ thoughts on nationalism and Turkish national identity who had tried to give an answer by searching for a new and unique Turkish humanism in general and particularly former Minister of Education, Hasan Ali Yücel’s period (1939-1946 and his humanist reformist approach to politics during the nation/identity-building process in the early decades of Republican Era. After the historical and social transition, French Revolution spreading the ideas of equality, liberty and fraternity giving rise to nationalist movements throughout Europe ended up with the decline of the multi-national empires and gave birth to the nation-states. Like the others, a new nation-state, Turkish Republic was established after the Ottoman Empire had collapsed. Turkish modernization initially took a form of westernization. Three ideologies; Pan-Ottomanism, Pan-Islamism and Pan-Turkism were seen as an appropriate direction for the society’s search for a new identity. At the same time, Turkish national identity was seen as an appropriate direction for the society’s search for a new identity and The republican elite embarked a radical stand and defined Turkish identiy as western modern secular nation which later became a dominant ideology for the new republic. At the time of early years of Republic, there were seen different acceptions for the content national identity. Hasan Ali Yücel and intellectuals searching for Turkish humanism defined modern Turkish identity by deriving it from Anatolian humanism, which could be realized through a Turkish Renaissance and claimed that it would be possible to create a unique Anatolian identity by this definition. Bu çalışma, Modern Türkiye tarihinin erken Cumhuriyet yıllarının ulus-devletleşme sürecinde milliyetçilik ve milli kimlik üzerine yaşanan tartışmalara katkıları açısından milli kimliğin içeriğini belirlemede Türkiye’ye özgü yeni bir

Hikâyet-i Nil-i Mübârek Üzerine The Story Of The Holy Nile

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Yusuf Ziya SÜMBÜLLÜ

2012-12-01

yakın temasa geçmiştir. Bu temas, öncelikle dil ve edebiyat sahasında etkili olmuştur. Tercüme ve adaptasyon faaliyetleri ile ivme kazanan bu kültürel etkileşim döneminde, dini-ahlâki-didaktik nitelikte pek çok eser, Türk Edebiyatı sahasında bu suretle var olabilmiştir. Bahsi geçen eserlerin ana hatlarıyla ideal insan, ideal toplum prensibi ekseninde, ağırlıklı olarak dini ve ahlâki içerikli bir kimlik ile karşımıza çıktığı ifade edilebilir ki bu türden eserlerden bir bölümünü de kıssalar oluşturur. Nîl Nehri���nin kaynağına duyulan merak ve bu merakın giderilmesi adına başlatılan dini-fantastik içerikli maceralı yolculuğu anlatan “Hikâye-i Abdülmecid” adlı kıssa da bahsi geçen türün özelliklerini barındıran bir eser olmakla çalışmamızın genel çerçevesini oluşturmaktadır. Bilinmeyene duyulan merak ve bu merakın giderilmesi adına söylenenler veya icra edilenler, ister istemez etraflarında dini, sihri, mistik olağanüstülüklerin iç içe geçerek işlenmesi sonucunu doğurabilir. “Hikâye-i Abdülmecid” adlı eserde, Abdülmecid’in Nil Nehri’nin kaynağını arayışı, halkın Cennet, Cebrail gibi dini konulardaki algısını yansıtıyor olmanın yanında, Kevser, Nil, Zemzem gibi suların kaynak olarak kutsal bir kökene nasıl bağlanmış olduğuna da işaret etmektedir. Nil Nehri, Fırat Nehri gibi “Mübarek” sıfatı ile yüceltilmiş ve İslâm nehri olarak sayılmıştır. Bu sıfat, nehrin Mısır ve havalisindeki bütün zirai hayatın doğal olarak da insan hayatının can damarı olması münasebetiyle olabileceği gibi, nehrin kaynağının oldukça uzun bir süre tespit edilememesiyle de ilgili olsa gerektir ki Nîl Nehri’nin kaynağının gizeminin oldukça eski ve sık işlenmiş bir tema olduğunu da burada ifade etmek gerekecektir.

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African Journals Online (AJOL)

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into S180 solid tumour model, grouped and administered. ... It was originally recorded in the "Shen Nong's Herbal Classic" (Xu, 1994) as top grade, bitter and pungent in taste, slightly ..... Modern Handbook of Practical Clinical Medicine.

Vitronectin Binds to a Specific Stretch within the Head Region of Yersinia Adhesin A and Thereby Modulates Yersinia enterocolitica Host Interaction.

Science.gov (United States)

Mühlenkamp, Melanie C; Hallström, Teresia; Autenrieth, Ingo B; Bohn, Erwin; Linke, Dirk; Rinker, Janina; Riesbeck, Kristian; Singh, Birendra; Leo, Jack C; Hammerschmidt, Sven; Zipfel, Peter F; Schütz, Monika S

2017-01-01

Complement resistance is an important virulence trait of Yersinia enterocolitica (Ye). The predominant virulence factor expressed by Ye is Yersinia adhesin A (YadA), which enables bacterial attachment to host cells and extracellular matrix and additionally allows the acquisition of soluble serum factors. The serum glycoprotein vitronectin (Vn) acts as an inhibitory regulator of the terminal complement complex by inhibiting the lytic pore formation. Here, we show YadA-mediated direct interaction of Ye with Vn and investigated the role of this Vn binding during mouse infection in vivo. Using different Yersinia strains, we identified a short stretch in the YadA head domain of Ye O:9 E40, similar to the 'uptake region' of Y. pseudotuberculosis YPIII YadA, as crucial for efficient Vn binding. Using recombinant fragments of Vn, we found the C-terminal part of Vn, including heparin-binding domain 3, to be responsible for binding to YadA. Moreover, we found that Vn bound to the bacterial surface is still functionally active and thus inhibits C5b-9 formation. In a mouse infection model, we demonstrate that Vn reduces complement-mediated killing of Ye O:9 E40 and, thus, improved bacterial survival. Taken together, these findings show that YadA-mediated Vn binding influences Ye pathogenesis. © 2016 S. Karger AG, Basel.

A case-control study of Yersinia enterocolitica infections in Auckland.

Science.gov (United States)

Satterthwaite, P; Pritchard, K; Floyd, D; Law, B

1999-10-01

To identify major risk factors for Yersinia enterocolitica (YE) and identify measures to reduce YE infections. A prospective case control study, group age matched, using 186 cases of YE identified by community pathology laboratories and 379 randomly selected controls. Conducted between April 1995 and June 1996 in Auckland, New Zealand. Face-to-face interviews used a standardised questionnaire examining exposures to factors potentially associated with YE infections including untreated water, unreticulated sewerage, consumption of selected foods, selected food handling practices and socio-demographic factors. Multivariate logistic regression was used to calculate adjusted odds ratios for the potential risk factors. Population attributable risk (PAR) was calculated for significant exposures. Having more than two people living in the home was more common among cases than controls (OR = 2.2). Town supply water (OR = 0.2), reticulated sewerage (OR = 0.34) and looking after a young child (OR = 0.51) were significantly less common. Of the meats, only pork (OR = 1.34) had a higher consumption rate, while bacon (OR = 0.75) and smallgoods (OR = 0.73) were consumed less frequently by cases than controls. Eating food from a sandwich bar was more frequent among cases (OR = 1.18). Fruit and vegetable consumption was marginally less (OR = 0.98). The population attributable risk of these factors was 0.89, implying that 89% of YE would be eliminated if adverse exposures were removed. The risk of YE illness is increased by contact with untreated water, unreticulated sewerage and consumption of pork. Investigation of non-town water supply, informal sewerage systems and methods of preparation and consumption of pork are recommended to determine how YE enters the human food chain.

Participación, comunidad y transformación: reflexiones desde el Centro Social Comunitario Luis Buñuel

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Jaime Andrés

2017-11-01

Full Text Available En este artículo reflexionamos sobre la relación entre acción comunitaria y transformación social en el ámbito de Psicología Comunitaria a partir del análisis de la experiencia del Centro Social Comunitario Luis Buñuel, iniciativa puesta en marcha por vecinas y vecinos en la ciudad de Zaragoza después de la irrupción del movimiento 15M en el contexto español en 2011. Los conceptos de participación y comunidad son discutidos a partir del diálogo entre los significados y prácticas desplegadas por esta iniciativa ciudadana y algunas perspectivas emergentes en el campo de la intervención social. Los debates planteados buscan abrir nuevos horizontes en la conceptualización de los procesos de intervención social explorando las nociones de articulación, involucración, lo cotidiano, lo común, la interdependencia y los cuidados. Se concluye con una serie con consideraciones relacionadas con las posibilidades que abre pensar la intervención social a partir de procesos comunitarios articulados desde la ciudadanía.

X-ray Crystallographic, Multifrequency Electron Paramagnetic Resonance, and Density Functional Theory Characterization of the Ni(P(Cy)2N(tBu)2)2(n+) Hydrogen Oxidation Catalyst in the Ni(I) Oxidation State.

Science.gov (United States)

Niklas, Jens; Westwood, Mark; Mardis, Kristy L; Brown, Tiara L; Pitts-McCoy, Anthony M; Hopkins, Michael D; Poluektov, Oleg G

2015-07-06

The Ni(I) hydrogen oxidation catalyst [Ni(P(Cy)2N(tBu)2)2](+) (1(+); P(Cy)2N(tBu)2 = 1,5-di(tert-butyl)-3,7-dicyclohexyl-1,5-diaza-3,7-diphosphacyclooctane) has been studied using a combination of electron paramagnetic resonance (EPR) techniques (X-, Q-, and D-band, electron-nuclear double resonance, hyperfine sublevel correlation spectroscopy), X-ray crystallography, and density functional theory (DFT) calculations. Crystallographic and DFT studies indicate that the molecular structure of 1(+) is highly symmetrical. EPR spectroscopy has allowed determination of the electronic g tensor and the spin density distribution on the ligands, and revealed that the Ni(I) center does not interact strongly with the potentially coordinating solvents acetonitrile and butyronitrile. The EPR spectra and magnetic parameters of 1(+) are found to be distinctly different from those for the related compound [Ni(P(Ph)2N(Ph)2)2](+) (4(+)). One significant contributor to these differences is that the molecular structure of 4(+) is unsymmetrical, unlike that of 1(+). DFT calculations on derivatives in which the R and R' groups are systematically varied have allowed elucidation of structure/substituent relationships and their corresponding influence on the magnetic resonance parameters.

AKILLI KARTLAR İLE YAPILAN MAL VE HİZMET SATIŞLARININ TMS-18 HASILAT STANDARDI ÇERÇEVESİNDE MUHASEBELEŞTİRİLMESİ-RECOGNITION OF SOLD GOODS AND SERVICES BY SMART CARDS WITHIN TMS-18 REVENUE STANDARD

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Abitter ÖZULUCAN

2012-06-01

Full Text Available Bu çalışmada;, önce akıllı kart / yemek çekleri sistemi tanıtılmakta, tarafların sağladıkları fayda ve maliyetler belirtilmekte ve gerçekleşen satış işleminin taraflarca kayda geçirilmesi hususu TMS 18 Hasılat standardı kapsamında ele alınmaktadır. Elde edilen hasılatın ölçümünde, sistemin işleyişinde temel unsur olan ve üye iş yeri tarafından yemek kartı tedavül eden işletmeye hizmet faturası karşılığında ödenen komisyonların, hasılatla doğrudan ilişkilendirilebilen bir gider niteliği taşıyıp taşımaması; bu türden giderlerin Tekdüzen Muhasebe Sistemi’nden farklı olarak, TMS 18 kapsamındaki ölçümünün ve muhasebeleştirilmesinin farklı olup olmadığının belirlenmesi amacıyla kaleme alınan bu çalışma, giriş ve sonuç bölümlerinin dışında dört bölümden oluşmaktadır.-The main part of the smart card system is sellers and while they are measuring of their revenue, they should associate the commissions with revenues to record at inception. So in this paper, after the smart card system is introduced, the advantages and disadvantages of this system are exposed and then how to recognise of the selling is considered within TMS 18, Revenues Standard. In other words, the reason that we conduct this paper can be expressed that the expense of the selling commissions which arise from the selling products with smart card whether should or should not deduct to revenue while the revenue is been measured.

TÜRKİYE'NİN FARKLI BÖLGELERİNDE ÜRETİLEN DEĞİŞİK TİPTE UNLARIN MİNERAL MADDE MİKTARLARI

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Raci EKİNCİ

2002-01-01

Full Text Available Bu araştırmada Türkiye'nin 7 ayrı bölgesine ait 19 farklı ilde un üretimi yapan 30 fabrikadan sağlanan (30 adet Tip 1, 30 adet Tip 2 ve 26 adet Tip 3 toplam 86 un örneğinin kalsiyum, potasyum, magnezyum, demir, çinko, bakır ve mangan miktarları açısından incelenmiştir. Un tipleri açısından ortalama mineral maddelerden; potasyum, magnezyum, demir, mangan değerleri arasında önemli farklılıklar olduğu, diğer özelliklerdeki farklılıkların ise istatistiksel olarak önemli olmadığı tespit edilmiştir. Farklı fabrikalara ait unların mineral maddelerden; kalsiyum, potasyum, demir, çinko, bakır, mangan değerleri arasındaki farklılıklar istatistiksel olarak önemli bulunmuştur.

Yazmada Etkililik: Kalem ve Klavyeye Yönelik Bir Karşılaştırma Writing Effectiveness: A Comparison of Pen and Keyboard

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Erol DURAN

2013-03-01

Full Text Available In this study, attempted to determine the effect Primary 5 and 8skill levels of students in writing narrative and informational text thatstudents are attending classes, computer usage levels and authoringtool (keyboard with a pen, scan model is used. Dependent variable inthis research is skill levels of students' writing. And classrooms,computer usage levels, and writing tools are independent variables. Inthis study, rather than other variables, investigate the effect of writing tool on writing. The study group students has been training in schoolsin Usak Province with high levels of socio-economic progress in primary5 (n=32 and 8 class (n=32. That students are attending classes,computer usage levels and variables authoring tool, both in narrativeand informative writing skill level of the common text has beenconcluded that the effect was not significant. However, the students'skill levels in narrative and informational text writing and writing toolthat students are attending classes differ statistically meaningful way. Itcan be said that primary 8 grade students, writing both narrative andinformational text type,are better than grade students from writing onscreen in primary 5 students writing skill levels. In addition, in bothwrting type, write with a pen on paper is is more effective than wrtingon screen in the development of students' writing skill level. İlköğretim 5 ve 8. sınıf öğrencilerinin hikâye edici ve bilgilendiricimetin yazma beceri düzeylerinin, öğrencilerin devam ettikleri sınıflar,bilgisayar kullanım düzeyleri ve yazma aracına (klavye ile kalem görefarklılaşıp farklılaşmadığını belirlemeye çalışılan bu çalışmada, taramamodeli kullanılmıştır. Öğrencilerin yazma beceri düzeyleri araştırmanınbağımlı değişkenini; devam ettikleri sınıflar, bilgisayar kullanımdüzeyleri, yazdıkları türler ve yazma araçları, araştırmanın bağımsızdeğişkenleridir. Bu çalışmanın asıl yap

Potential Ameliorative Effects of Qing Ye Dan Against Cadmium Induced Prostatic Deficits via Regulating Nrf-2/HO-1 and TGF-β1/Smad Pathways.

Science.gov (United States)

Du, Lifen; Lei, Yongfang; Chen, Jinglou; Song, Hongping; Wu, Xinying

2017-01-01

Cadmium (Cd) is an environmental pollutant with reproductive toxicity. Swertia mileensis is used in Chinese medicine for the treatment of prostatic deficits and named as Qing Ye Dan (QYD). This study was undertaken to investigate the potential protective effects of QYD against Cd-induced prostatic deficits. Rat model of prostatic deficits was induced by 0.2 mg/kg/d CdCl2 subcutaneous injection for 15 days. The prostatic oxidative stress was evaluated by detecting the levels of malondialdehyde, nitric oxide, reduced/ oxidized glutathione, total sulfhydryl groups and enzymatic antioxidant status. The prostatic inflammation was estimated by testing the levels of pro-inflammatory cytokines. The levels of epithelial-mesenchymal transition (EMT) markers E-cadherin, fibronectin, vimentin and α-smooth muscle actin were measured by qPCR analysis. Additionally, the prostatic expressions of transforming growth factor-β1 (TGF-β1), type I TGF-β receptor (TGF-βRI), Smad2, phosphorylation-Smad2 (p-Smad2), Smad3, p-Smad3, Smad7, nuclear related factor-2 (Nrf-2), heme oxygenase-1 (HO-1), B-cell CLL/lymphoma (Bcl)-2 and Bcl-2-associated X protein (Bax) were measured by western blot assay. It was found that QYD ameliorated the Cd-induced prostatic oxidative stress and inflammation, attenuated prostatic EMT, inhibited the TGF-β1/Smad pathway, increased Bcl-2/Bax ratio and enhanced the activity of Nrf-2/HO-1 pathway. These results showed that QYD could ameliorate Cd-induced prostatic deficits via modulating Nrf-2/HO-1 and TGF-β1/Smad pathways. © 2017 The Author(s). Published by S. Karger AG, Basel.

Çocuk Kitaplarında Mülteciler ve Kültürleşme Stratejileri- Refugees and Acculturation Strategies in Children’s Books

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Elif Emine BALTA

2018-04-01

Full Text Available İnsanın veya insanların sosyal, ekonomik, siyasi veya başka sebeplerden dolayı yaşadıkları yerden farklı bir yere doğru hareket etmesi veya yerleşmesi olarak tanımlanabilen göç, insanın varoluşundan bu yana olan bir hadisedir. Göç, ister ilkel ister günümüzdeki örnekleri gibi karmaşık olsun insanların daha iyiyi arama bulma çabasından kaynaklanmaktadır. Buna rağmen göçe karar verme, göç süreci ve sonrasında yeniye alışma ve uyum sağlama zorluklarla doludur. Çocuğun küresel dünyanın bir parçası olması, toplumsal sorunların farkında olması, farklı insan, yaşayış ve kültürlerin var olabileceğinin bilincinde olması ve önyargılarından arınması için sosyal problemlerin örnekleriyle karşılaşması gerekmektedir. Türk çocuk edebiyatında son birkaç yılda mülteci ve sığınmacı göçleri ile ilgili konuların işlendiği görülmektedir. Bu çocuk kitapları, mültecilerin toplumsal kabul görmeleri noktasında düşünülerek yazılmış, toplumda farkındalık yaratmayı amaçlayan bir anlamda güdümlü eserler olarak karşımıza çıkmaktadır. Çocukların empati yapabilmelerine imkân tanıyacak eserlerin varlığı bu bağlamda sevindiricidir. Bu çalışmada, Umut Sokağı Çocukları, Kömür Karası Çocuk, Kuş Olsam Evime Uçsam, Juju Beni Unutma, Halepli Zeynep adlı kitaplar kültürleşme modeli perspektifinden değerlendirilmiştir. Türk toplumunun, özellikle çocukların vicdanına seslenen bu kitapların ortak noktasının mültecileri anlamak için çaba göstermeye odaklanma olduğu söylenebilir. Mültecilerin göç etme ve Türkiye’ye uyum sağlama süreçlerinde yaşadıkları, duygu ve düşünceleri çocuk bakış açısıyla sunulmuştur. Bununla birlikte Türk halkının mültecilere tavrının ve bu tavrın çocuk ruhuna yansımasının gerçekçi biçimde aktarıldığını söylemek mümkündür.

Apgrozījuma prognozēšana ar mākslīgo neironu tīklu palīdzību

OpenAIRE

Puškina, Tatjana

2012-01-01

Bakalaura darba pētījumu ietvaros tika analizēta mākslīgo neironu tīklu programmas izvēle Latvijas uzņēmuma „Pasaules Optika” apgrozījuma prognozēšanai, kā arī veikta tā praktiskā pielietošana. Darbs sastāv no trim nodaļām, kurās tiek izskatītas problēmas, kas ir iespējams risināt ar mākslīgo neironu tiklu palīdzību, izmantojot Neuro XL programmu. Salīdzinājumā ar citām mākslīgā intelekta risinošam datu apstrādes programmām tiek novērtēts Neuro XL programmas priekšrocības, tiek imitēti ikgadē...

Naudas atmazgāšana būtība, mehānismi un ietekme uz komercattiecību vidi Eiropā

OpenAIRE

Tilcēns, Mārtiņš

2016-01-01

Mūsdienās ikvienas valsts izaicinājums ir cīņa ar tādu ēnu ekonomikas parādību kā naudas atmazgāšana. Aizvien pieaugot vispārējai globalizācijas tendencei, mainoties gan starptautiskajiem, gan valstu iekšējiem likumiskajiem regulējumiem, attīstoties tehnoloģiskajām iespējām un noziegumu īstenotāju izdomai, šī cīņa kļūst aizvien sarežģītāka. Bakalaura darba mērķis ir parādīt noziedzīgi iegūto līdzekļu atmazgāšanas nozīmi un ietekmi uz ekonomiskajām sistēmām. Bakalaura darbs sastāv no trim da...

Tezkire-i Buğra Han’ın Çağatayca Yazılmış Bir Nüshası Metin- Dil İncelemesi- Tıpkıbasım A Manuscript Of Tazkira-i Bughra Khan Written In Chagatay Turkısh Texte- Grammar Notes- Facsimile

Directory of Open Access Journals (Sweden)

B. Erdem DAĞISTANLIOĞLU

2012-12-01

ındaki bilgiler oldukça sınırlıdır. Bu dönem hakkındaki bilinmezliklerin benzeri, İslamiyet’in Türkler arasında yayılmasında büyük bir yeri bulunan ve efsanevi özellikler taşıyan Satuk Buğra Han için de geçerlidir.Bu makale, Türklerin İslamiyeti kitle hâlinde kabul edişlerini ve ilk Müslüman Türk hükümdarının efsanevi hayatını anlatan Tezkire-i Buğra Han kitabının 19. yüzyılda Çağatayca olarak kaleme alınmış bir nüshasının çeviri yazı ve dil incelemesini içermektedir.Çalışmamıza konu olan eser, Klasik Çağataycanın dil özelliklerini taşımakla beraber, Özbekçe ve Çağdaş Uygurcanın ses ve şekil bilgisi özelliklerini de barındırmaktadır. Tezkire-i Buğra Han kitabı gerek ses gerekse şekil bilgisi bakımından Çağatayca öncesi arkaik örnekleri de içermektedir. Eser bu özellikleriyle, hem Çağataycadan çağdaş Türk lehçelerine geçişi yansıtmakta hem de içerdiği arkaik yapılarla dikkat çekmektedir.Yazmanın Çağatayca dışında en çok Çağdaş Uygurcanın dil özelliklerini barındırdığı görülmektedir. Kitabın ilk sayfasındaki karışık bir hâlde yazılmış ifadelerin içinden tespit edebildiğimiz tārįħķa bir min g iki yüz yėtmiş1 ….. inal aķsuluķ taĥrįri āħir boldı cümlesi eserin Çağdaş Uygurcayla olan bağını da açıklar niteliktedir.Bu makalede söz konusu yazma eserin bütünü hakkında, yazarı, yazıldığı yüzyıl, diğer nüshaları vb. özellikleri bakımından bilgi verilmiş olup yalnızca Satuk Buğra Han menkabesinin geçtiği kısmın çeviri yazılı metni sunulmuştur. Ayrıca incelenen kısmın tıpkıbasımı da makalenin sonuna eklenmiştir.Bu yazıda, British Library’deki Or. 8161 numaralı metnin 83a-102b varakları arasındaki Satuk Buğra Han menkabesini esas almakla birlikte, dil incelemesinde gerek duyuldukça yazmanın bütünü göz önünde bulundurularak açıklamalar yapılmıştır.

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African Journals Online (AJOL)

cadewumi

... and was originally recorded in the "Shen Nong's Herbal Classic". Wild ... treatment groups were intragastrically administered with 0.2 ml of Pinellia ternata ... P<0.05; on the 14th day after administration P<0.01). ... A large number of modern.

Supplement table 1 Collection localities of C. mystaceus in Thailand.

Indian Academy of Sciences (India)

Acer

. 2, CPm, 5, Chaiyaphum, Mueang, Northeast. 3, KKk, 5, KhonKaen, Kranuan, Northeast. 4, KKm, 5, KhonKaen, Mueang, Northeast. 5, KKu, 4, KhonKaen, Ubolratana, Northeast. 6, KSh, 3, Kalasin, HuaiMek, Northeast. 7, LEn, 1, Loei, NongHin ...

Reading Intermediality: Lorca’s Viaje a la luna (“Journey to the Moon,” 1929 and Un chien andalou (Buñuel/Dalí, 1929

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Paul Julian Smith

2014-10-01

Full Text Available This article will treat two experimental short films, the first one of the most famous in cinema history; the second a little known script, lost for many years and brought to the screen only sixty years after it was written. The former is Un chien andalou of 1929, generally attributed to both director Luis Buñuel and Catalan painter Salvador Dalí (who claims first screenwriting credit in the film itself. The latter is Viaje a la luna, written also in 1929 by poet and dramatist Federico García Lorca and filmed by Frederic Amat, a contemporary Catalan painter, in 1998, the centenary of Lorca’s birth. Normal 0 false false false EN-US JA X-NONE

Ekonomiskās reformas ietekme uz uzņēmējdarbību: Ķīna un Krievija līdz 1992.gadam

OpenAIRE

Zūle, Anda

2009-01-01

Mūsdienās daudzi ir aizmirsuši, ka pirms 20-30 gadiem pasaules ekonomika piedzīvoja milzu izmaiņas, kad divas komunistiskās valstis – Ķīna un Padomju Savienība – izlēma uzsākt ekonomisko pāreju no komandekonomikas uz tirgus ekonomiku. Diplomdarba pētījuma mērķis ir analizēt divu ekonomiskās reformas stratēģiju atšķirīgo ietekmi uz uzņēmējdarbības procesiem valstij pārejot no komandekonomikas uz tirgus ekonomiku. Lai analizētu un aprakstītu reformu ietekmi uz uzņēmējdarbību, tiek izmantots Ķīn...

Structure-activity relationship of linear peptide Bu-His6-DPhe7-Arg8-Trp9-Gly10-NH2 at the human melanocortin-1 and -4 receptors: DPhe7 and Trp9 substitution.

Science.gov (United States)

Danho, Waleed; Swistok, Joseph; Cheung, Adrian Wai-Hing; Kurylko, Grazyna; Franco, Lucia; Chu, Xin-Jie; Chen, Li; Yagaloff, Keith

2003-02-24

A series of pentapeptides, based on hMC4R pentapeptide agonist (Bu-His(6)-DPhe(7)-Arg(8)-Trp(9)-Gly(10)-NH(2)), was prepared in which either DPhe(7) or Trp(9) residue was systematically substituted. A number of interesting DPhe surrogates (D-Thi, D-3-CF(3)Phe, D-2-Nal and D-3,4-diClPhe) as well as Trp surrogates (2-Nal and Bta) were identified in this study.

AN ANALYSIS ABOUT A STORY IN NERGISÎ’S MEŞÂKKU’L-‘UŞŞÂK NERGİSÎ’NİN MEŞÂKKU’L-‘UŞŞÂK’INDAKİ BİR HİKÂYEYİ TAHLİL DENEMESİ

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Nazmi ÖZEROL

2012-01-01

Full Text Available This study consists of the introduction and four parts. In the introduction part, there is information about storytelling in general and the Classical Turkish storytelling; and Nergisî’s importance in storytelling tradition and his book Meşâkku’l-‘uşşâk have been mentioned. There is the summary of the story in the first part. Including content elements; the story, narrator, perspective, time, place, people are in the second part. Portraits and dialogues have been emphasized in the third part together with the analysis of narrating techniques and there is the analysis of the language of the story and storytelling mode in the fourth part Bu çalışma giriş ve dört bölümden oluşmaktadır. Giriş bölümünde genel anlamda hikâye ve Klâsik Türk hikâyeciliği hakkında bilgi verilerek Nergisî’nin bu gelenekteki öneminden ve Meşâkku’l-‘uşşâk adlı eserinden bahsedilmiştir. Birinci bölümde hikâyenin özeti verilmiş, ikinci bölümde muhteva unsurları kapsamında; olay, anlatıcı ve bakış açısı, zaman, mekân, şahıs kadrosu ele alınmıştır. Üçüncü bölümde anlatım teknikleri incelemesi yapılarak tasvir ve diyaloglar üzerinde durulmuş, dördüncü bölümde hikâyenin dil ve üslup incelemesi yapılmıştır.

KADIN YOKSULLUĞU VE KADIN SAĞLIĞI ÜZERİNE YANSIMALARI

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Seda KOCABACAK

2014-08-01

Full Text Available Cinsiyet eşitsizliği, yoksulluk ve iyi olmayan sağlık durumunun önemli nedenlerinden biridir. Kadınlar sosyal hayatın birçok alanında cinsiyet ayrımcılığı ile karşı karşıya kalırlar: sağlık hizmetlerinden yararlanma, eğitim, istihdam koşulları, sosyal ve ekonomik yaşam, politik haklar ve ahlaki sorumluluklar bunların bazılarıdır. Bazı toplumsal kabuller ya da ailelerin ekonomik zorlukları kız çocukların okuldan uzak kalmasına yol açabilmektedir. Eğitimsizlik ya da yetersiz eğitim ise özel nitelikler gerektirmeyen ya da düşük gelir sağlayan işlerde çalışılmasına yol açmaktadır. Bu kısıtlılıklar ve eşitsizlikler kadın sağlığı ve refahı üzerinde doğrudan ya da dolaylı etkilere sahiptir. Eğitimli ve refah sahibi kadınlar kadın sağlığı, çocuk sağlığı, aile sağlığı ve hatta tüm toplumun sağlığının geliştirilmesine katkı sağlarlar. Bu çalışmanın amacı ilk olarak kadın yoksulluğu ve sağlığı arasındaki ilişkiyi tartışmak ve Türkiye’ye ilişkin verilerle değerlendirmeler yapmaktır.

Yerel E-Katılımın Yeni Aracı Olarak Sosyal Ağlar: Facebook ve Twitter Örneği

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Levent MEMİŞ

2015-04-01

Full Text Available Bu araştırmada, son yıllarda örgütleri ve bireylerin iletişim veya etkileşim sürecine yeni bir hız kazandıran sosyal ağların, daha da özelde Facebook ve Twitter araçlarının, belediye örgütleri ve belediye başkanları düzeyinde, yerel kamusal politikalara katılım bağlamında, “ne düzeyde” ve “nasıl” kullanıldığının ortaya çıkarılmasına çalışılmıştır. Bu kapsamda, kişisel düzeyde 6 belediye başkanının Facebook ve 12 belediye başkanının Twitter; kurumsal düzeyde ise 22 belediyenin Facebook ve yine 22 belediyenin Twitter hesabı araştırma kapsamında niteliksel içerik analizi yöntemiyle incelenmiştir. Çalışmanın genel sonuçlarına göre, kişisel Twitter hesaplarında sorunları ileten/bilgi talep eden etkileşim öne çıkmakla birlikte, hesaplardaki üye sayısı dikkate alındığında sınırlı düzeyde etkileşimin olduğu, daha çok katılımın ilk evresi olarak kabul edilen bilgi aktaran, doğrudan katılımı teşvik etmeyen biçiminde kullanıldığı tespit edilmiştir.

Stanisław Bułak-Bałachowicz. Postać, która mogła połączyć narody byłego Wielkiego Księstwa Litewskiego, a jednak ich nie połączyła

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Joanna Gierowska-Kałłaur

2017-12-01

Full Text Available Stanisław Bułak-Bałachowicz. He who could have united the nations of the former Grand Duchy of Lithuania, yet did not Revered, fluent in all Borderland languages, an excellent soldier; Stanisław Bułak-Bałachowicz, back when he was a subordinate of Nikolai Yudenich, tried to rename the unit under his command to the "People's Army", or in other words, the Territorial or National Army. The territorial understanding of "Belarusness", in conjunction with the nearly atavistic antibolshevism of Bałachowicz, were a great asset in Józef Piłsudski's new political combination. Piłsudski decided to benefit from Savinkov's idealistic approach for his own purpose. The Russian Political Committee, Bałachowicz's troops and the statements of Vyacheslav Adamovich (father were to support the establishment of Belarus for Belarusians. Not under Kaunas and Berlin, nor a Soviet one. A “Third Belarus”. A Belarus friendly towards Poland. Following discussions with Savinkov, the builder of the "Third Russia", Piłsudski engaged himself after 6 March 1920 (Millerand Note in supporting (inter alia financially the Russian Political Committee. Based on the agreement of the Polish Supreme Command with B.V. Savinkov, all Russian formations on the Polish territory were subordinated politically to B. Savinkov. On 27 August 1920, on the orders of the Supreme Command, Bałachowicz entered a secret agreement with Savinkov. They both were also to seek convening the Constituent Assembly, providing land for the people and democracy, and to create a Union of Nations (i.e., a federation. In the event of Bałachowicz's unit succeeding "deeper into Russian territory", the local government and the administrative board were to be founded on his authority. This is how Bułak-Bałachowicz was to become the executor of the first phase of Piłsudski's new "concept for Belarus".   Stanisław Bułak-Bałachowicz. Postać, która mogła połączyć narody byłego Wielkiego Ksi

RELATIONSHIPS BETWEEN GENETIC POLYMORPHISM AND DRUG: FORENSIC PHARMACOGENETIC

OpenAIRE

Çevik, Filiz Ekim; Balcıoğlu, Yasin Hasan; Karadayı, Şükriye; Çakan, Hüseyin

2015-01-01

Filiz Ekim ÇEVİK1, Yasin Hasan BALCIOĞLU1, Şükriye KARADAYI2, Hüseyin ÇAKAN1 1İstanbul University, Forensic Medicine Institute, TÜRKİYE 2İstanbul University, Public Health Directorate, TÜRKİYE

ÖRGÜTSEL MUHALEFET ÖLÇEĞİNİN TÜRKÇE’ YE UYARLANMASI: GEÇERLİK VE GÜVENİRLİK ÇALIŞMASI

OpenAIRE

DAĞLI, Abidin

2015-01-01

Bu araştırmanın amacı, Kassing (2000) tarafından geliştirilen Örgütsel Muhalefet Ölçeği’nin (ÖMÖ) Türkiye koşullarında geçerlik ve güvenirlik çalışmasını yapmaktır. Özgün ölçek İngilizce olup, iki faktörlü bir yapı altında toplam 18 maddeden oluşmaktadır. Uyarlama çalışması için öncelikle orijinal ölçeğin Türkçeye çevirisi yapılmış, daha sonra dil, içerik, ölçme ve değerlendirme alanlarındaki uzmanların görüşlerine sunulmuştur. Uzmanların önerileri doğrultusunda ölçek üzerinde bazı değişiklik...

Ferhat İle Şirin Hikâyesi’nde Büyülü Gerçekçilik Magical Realism In The Tale Of Ferhat And Şirin

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Mehmet Emin BARS

2012-12-01

depths of oral literature. In our study, in the writing work, placed in Seyfettin Özege bookcase in Atatürk University Central Library by the name of the tale of Ferhat and Şirin, the being of the style of magical realism is going to be studied. Halk hikâyeleri, göçebelikten yerli hayata geçişin ilk mahsullerindendir. Genellikle aşk ve kahramanlık konularını işlerler. Kaynağını Türk, Arap-İslam ve Hint-İran kültüründen alan bu ürünler, büyük ölçüde âşıklar ve meddahlar tarafından anlatılan nazım nesir karışık anlatımlardır. Türk halk hikâyeleri milletimizin roman ihtiyacını karşılayan eserlerdir. Ferhat ile Şirin hikâyesi de uzun yıllar halkın bu ihtiyacını karşılamıştır. Ferhat ile Şirin hikâyesi İran edebiyatının mesnevi konuları arasında önemli yer tutar. Hüsrev ü Şirin adıyla da bilinen hikâye divan edebiyatında da mesnevi konusu olarak işlenmiştir. Hikâye halk edebiyatında Ferhat ile Şirin adıyla anılmıştır. Ferhat ile Şirin hikâyesi, Hüsrev ü Şirin mesnevisinin bir parçasıdır. Hüsrev ü Şirin mesnevisinin konusu Sasani hükümdarlarından Hüsrev Perviz’in hayatına ve aşk maceralarına dayanmaktadır. Hikâye yüksek zümre edebiyatında olduğu gibi halk edebiyatında da ele alınmış ve geniş halk kitleleri tarafından beğenilerek dinlenmiştir. Hikâye yazılı metinlerden sözlü edebiyata geçişte bazı değişikliklere uğramış, birçok varyantı meydana gelmiş, hikâyenin tarihî ve coğrafî çerçevesi de değişerek bir kısmı Anadolu’ya adapte edilmiştir. Büyülü gerçekçilik terimi ise, ilk olarak Alman sanat eleştirmeni ve tarihçisi Franz Roh tarafından, 1925’te dönemin Alman ressamlarının, konuları ve temaları hayal ürünü, fantastik ve rüyamsı niteliğe sahip çalışmalarını anlatmak amacıyla kullanılmıştır. Terim, edebiyatta ilk olarak, İtalyan yazar ve eleştirmen Massimo Bontempelli tarafından kullanılmıştır. Bu

Anemia and intestinal parasite infection in school children in rural Vietnam

NARCIS (Netherlands)

Thi, Le H.; Brouwer, I.D.; Verhoef, H.; Khan, N.C.; Kok, F.J.

2007-01-01

Objectives: This study hypothesized that besides iron deficiency, intestinal parasites infection is also a determinant of anemia in schoolchildren in rural Vietnam. Methods: 400 primary schoolchildren from 20 primary schools in Tam Nong district, a poor rural area in Vietnam, were randomly selected

Da-Bu-Yin-Wan and Qian-Zheng-San to Neuroprotect the Mouse Model of Parkinson’s Disease

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Xiao-Gang Gong

2014-01-01

Full Text Available Da-Bu-Yin-Wan (DBYW and Qian-Zheng-San (QZS, two classic traditional Chinese medicinal formulas, were clinically employed to treat Parkinson’s disease (PD. Our previous studies demonstrated neuroprotective effects of them on mitochondrial function in PD mice induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP. The purpose of this research was to investigate their possible mechanisms in the light of mitochondrial ATP-sensitive potassium (mitoKATP channels. The neuroprotective effect of DBYW and QZS on dopamine (DA neurons in substantia nigra (SN in the MPTP-induced PD mice was investigated by behavioral test (pole test and immunohistochemistry. Adenosine triphosphate (ATP level in the midbrain tissue was detected by firefly luciferase method. MitoKATP channel subunits SUR1 and Kir6.2 mRNA and protein expressions were tested by real-time PCR (RT-PCR and Western blot. It was observed that DBYW and/or QZS served to ameliorate MPTP-induced behavioral impairment and prevent the loss of substantia nigra dopamine neurons, as well as increase ATP level in the midbrain tissue and downregulate SUR1 expression at mRNA and protein levels with no marked influence on Kir6.2. We concluded that DBYW and QZS exhibit neuroprotective effects probably through the regulation of ATP level and mitoKATP channel subunit expressions.

Modern contraceptive use among women living with HIV/AIDS at the Korle Bu Teaching Hospital in Ghana.

Science.gov (United States)

Samba, Ali; Mumuni, Kareem; Adu, Joseph A; Sefogah, Promise E; Kudzi, William; Nartey, Edmund T

2018-04-01

To examine factors influencing contraceptive use among women living with HIV/AIDS. The present cross-sectional study included a randomly selected sample of sexually active females aged 15-60 years who were living with HIV/AIDS and receiving care at the HIV Clinic, Korle Bu Teaching Hospital, Accra, Ghana, between September 1 and November 31, 2016. Data were collected via a structured interviewer-administered questionnaire. Among 202 women who completed the survey, 50 (24.7%) were using contraceptives. Of the women using contraception, 39 (78%) were married and 6 (12%) were cohabiting. Twenty-eight (56%) reported that their primary sexual partners were HIV-positive, 14 (28%) had HIV-negative partners, and 8 (16%) did not know their partner's HIV status. Condoms were used by 42 (84%) women and the majority (41 [82%]) wanted to have more children; almost all (47 [94%]) had received counseling on contraceptive use. Overall, 133 (65.8%) and 45 (22.3%) women reported that they would prefer to share their family planning concerns with a doctor and nurse, respectively, at the HIV clinic. Women living with HIV/AIDS desired more children but preferred to share their family planning concerns with their clinician at the HIV clinic. Integrating HIV care and reproductive health services could help these women achieve childbearing goals safely. © 2018 International Federation of Gynecology and Obstetrics.

Outcomes of a Postexposure Prophylaxis Program at the Korle-Bu Teaching Hospital in Ghana: A Retrospective Cohort Study.

Science.gov (United States)

Tetteh, Raymond A; Nartey, Edmund T; Lartey, Margaret; Mantel-Teeuwisse, Aukje K; Leufkens, Hubert G M; Nortey, Priscilla A; Dodoo, Alexander N O

2015-01-01

The risk for occupational exposure to HIV is a serious public health problem that is well characterized in the developed world, but less so in the developing countries such as Ghana. This study was undertaken to examine the characteristics of occupational exposure to HIV and the utilization of a risk assessment system (RAS)-based postexposure prophylaxis (PEP) among health care workers (HCWs) and health care students (HCSs) in the Korle-Bu Teaching Hospital (KBTH). During the study period (January 2005-December 2010), a total of 260 and 35 exposures were reported by HCWs and HCSs, respectively. Ward attendants reported the highest incidence rate of 6.46 of 100 person-years (P-Y). The incidence of high-risk exposures was 0.33 of 100 P-Y (n = 65); 60.0% occurred during a procedure of disposing of a needle and 24.6% during a cannula insertion. A total of 289 of the 295 individuals were administered PEP, of which 181 (62.6%) completed the 6-month follow-up testing schedule and none sero-converted. This shows that with a good RAS in place, it is possible to deploy an effective PEP program in a typical African teaching hospital like the KBTH in Accra, Ghana. © The Author(s) 2013.

Reasons for not receiving thrombolytic therapy in patients with acute myocardial infarction admitted to Bu-Ali Sina Hospital in Qazvin (2013-14

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MM. Daei

2017-04-01

Full Text Available This hospital-based cross-sectional study was conducted in 2013-14 in Qazvin Bu-Ali Sina Hospital. 170 patients with acute myocardial infarction who not receiving thrombolytic therapy entered the study and were analyzed. Medical history, physical examination, twelve lead ECG and cardiac biomarkers were obtained. The mean age of the patients was 63.4±14.4 years (from 19 to 90 years. 110 (64.7% of the patients were male and 48 (28.2% were diabetic. 86 (50% of patients due to late presentation and 47 (28% due to lack of diagnosis and 29 (17% due to contraindication and 8 (5% due to autolysis or coronary spam were not received thrombolytic therapy. We could reduce failure of receiving thrombolytic therapy more than seventy five percent with increasing people's awareness about the symptoms of myocardial infarction and skills of health staff in relation to the proper and timely diagnosis of myocardial infarction.

Chemical composition, nitrogen degradability and in vitro ruminal biological activity of tannins in vines harvested from four tropical sweet potato (Ipomoea batatas L.) varieties.

Science.gov (United States)

Ali, R; Mlambo, V; Mangwe, M C; Dlamini, B J

2016-02-01

This study investigated the potential of vines from four sweet potato varieties (Tia Nong 57, Tia Nong 66, Ligwalagwala and Kenya) as alternative feed resources for ruminant livestock. The chemical composition [neutral detergent fibre (NDF), acid detergent fibre (ADF), crude protein (CP) and acid detergent insoluble nitrogen (ADIN)], in vitro ruminal nitrogen (N) degradability and in vitro ruminal biological activity of tannins in the vines, harvested at 70 and 110 days after planting (DAP), were determined. Variety and harvesting stage did not (p > 0.05) influence CP and NDF content of the vines. Concentration of CP ranged from 104.9 to 212.2 g/kg DM, while NDF ranged from 439.4 to 529.2 g/kg DM across harvesting stages and varieties. Nitrogen degradability (ND) at 70 and 110 DAP was highest (p ruminal cumulative gas production parameters (a, b and c). The in vitro ruminal biological activity of tannins, as measured by increment in gas production parameters upon PEG inclusion, had a maximum value of 18.2%, suggesting low to moderate antinutritional tannin activity. Ligwalagwala vines, with highly degradable N, would be the best protein supplement to use during the dry season when ruminant animals consume low N basal diets and maintenance is an acceptable production objective. Tia Nong 66 and Kenya varieties, with less degradable N, may be more suitable for use as supplements for high-producing animals such as dairy goats. Journal of Animal Physiology and Animal Nutrition © 2015 Blackwell Verlag GmbH.

Investigation of Possible Tsunami Events on the Eastern Coast of Taiwan: Case Studies of Lu-Ye, Changping, and Tulan.

Science.gov (United States)

Laksono, A. T., Jr.; Tsai, L. L. Y., Sr.

2017-12-01

Major earthquakes had occurred in eastern Taiwan for many times. According to an Amis folklore originated in Chengkong City, there was a big sea wave struck their settlement in 1850 AD. Several studies had been conducted, however, the evidence which indicates the tsunami was very weak. There is also a possibility that big sea waves had occurred due to typhoons which take place 3-4 times a year in Taiwan. The purpose of this study is to prove the possibility of tsunami events on the eastern coast of Taiwan based on sedimentological features. The methods in this study are facies analysis including observation of the marine terrace along Lu-Ye, Changping, and Tulan, identification of lithology, sedimentary structure, and fossil content. Lithology analysis is conducted by using point counting of 12 sandstone samples from marine terrace outcrops. Based on the field observation, we found a thin sand marine deposit included in the beach gravel at a height of 10 meters at the Changping marine terrace. It contains coral and some Mollusca shells and does not display any particular sedimentary structure. Sediments that have similar characteristics were also found in the Tulan marine terrace with a height of 5 m. In addition, fossil analysis of marine sand in Tulan exhibits the presence of several planktonic foraminifera fossils such as Orbulina bilobata and Globigerinoides ruber. Temporary interpretation indicates that there is a "super" event which transports shallow marine and beach materials subsequently deposit them on top of an alluvial fan. A 10 cm thin layer of sediment serves as an early tsunami indicator. In addition, the absence of deposits with the same characteristics further indicates that the event occurred only once. Since the eastern coast of Taiwan is an uplift zone with an uplift rate between 5-8 mm/year, the estimated wave height of tsunami should take into account both the tsunami age and the uplift rate. Furthermore, based on the distance from the

How Do the Metabolic Effects of Chronic Stress Influence Breast Cancer Biology?

Science.gov (United States)

2012-04-01

Paul A. Volden, Erin L. Wonder, Maxwell N. Skor, Christopher M. Carmean, Honggang Ye, Masha Kocherginsky, Eleanor Smith, Steven Kregel, Martha K...Wonder, Maxwell N. Skor, Christopher M. Carmean, Honggang Ye, Masha Kocherginsky, Steven Kregel, Martha K. McClintock, Matthew J. Brady, and Suzanne

Prevalence, serotype, virulence characteristics, clonality and antibiotic susceptibility of pathogenic Yersinia enterocolitica from swine feces

Science.gov (United States)

Introduction: Swine are the only known animal reservoir of Yersinia enterocolitica (YE), a human pathogen. Since YE is a fecal organism of swine, the primary goal of this study was to evaluate the prevalence, serotype, virulence plasmid (pYV)-associated characteristics, clonality, and antibiotic su...

Lexikos - Vol 12 (2002)

African Journals Online (AJOL)

Loan Words versus Indigenous Words in Northern Sotho — A Lexicographic Perspective · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. S Nong, G-M de Schryver, DJ Prinsloo,. http://dx.doi.org/10.5788/12-0-758 ...

Quantitative Study of Porosity and Pore Features in Moldavites by Means of X-ray Micro-CT

Czech Academy of Sciences Publication Activity Database

Pratesi, G.; Caporali, S.; Loglio, F.; Giuli, G.; Dziková, L.; Skála, Roman

2014-01-01

Roč. 7, č. 4 (2014), s. 3319-3336 ISSN 1996-1944 R&D Projects: GA ČR GA205/09/0991 Institutional support: RVO:67985831 Keywords : tomography * tektites * moldavites * Muong Nong * plastic deformation Subject RIV: DB - Geology ; Mineralogy Impact factor: 2.651, year: 2014

The introduction of oil palm in Northeast Thailand: a new cash crop for smallholders?

NARCIS (Netherlands)

Somnuek, Siriluk; Slingerland, M.A.; Grünbühel, C.M.

2016-01-01

As part of the Thai Government’s objective to increase energy security through biodiesel, oil palm was introduced to Northeast Thailand in 2005. Nong Khai Province was selected as a pilot project because of its suitable environmental conditions. This study assesses the acceptance of policy

Shielding design of a brachytherapy unit at the Korle Bu teaching hospital in Ghana: Comparison of theoretical calculations and experimental study

International Nuclear Information System (INIS)

Arwui, C. C.; Schandorf, C.; Nani, K.; Darko, E. O.; Deatanyah, P.

2010-01-01

A theoretical study was carried out to re-evaluate the integrity of the biological shielding of 137 Cs brachytherapy unit at the Korle Bu Teaching Hospital (Ghana), and the results were verified by measurement of the dose rates at selected locations. The primary objective was to determine the current state of protection and safety of staff and the general public. Shielding design of the brachytherapy unit at the hospital was based on postulated workload and occupancy factors of the facility. The facility has been in existence for 12 y and has accumulated operational workload data that differs from the postulated one. The results show that despite the variation in actual and postulated workloads, the dose rates were below the reference values 0.5 mSv h -1 for public areas and 7.5 μSv h -1 for controlled areas. These values were in the range of 0.10-0.12 μSv h -1 for public areas and of 0.50-2.10 μSv h -1 for controlled areas. (authors)

Detection of Yersinia enterocolitica serotype O:9 in the faeces of cattle with false positive reactions in serological tests for brucellosis in Ireland.

Science.gov (United States)

O'Grady, Don; Kenny, Kevin; Power, Seamus; Egan, John; Ryan, Fergus

2016-10-01

Intestinal infection by Yersinia enterocolitica serotype O:9 (YeO9) in cattle has been linked to false positive serological reactivity (FPSR) in diagnostic tests for brucellosis. Although eradicated in Ireland, brucellosis monitoring still identifies seropositive animals, usually one or two (termed singletons) per herd, which are classed as FPSR. To investigate a link between FPSR and YeO9, faeces and blood were collected from singleton FPSR cattle, and from companion animals, in eight selected herds with more than one FPSR animal, for YeO9 culture and Brucella serology. YeO9 was isolated from 76/474 (16%) FPSR singletons in 309 herds, but not from any of 621 animals in 122 control non-FPSR herds. In the FPSR herds 52/187 (27.8%) animals were culture positive, and 17% of the isolates were from seronegative animals. Seropositive animals were more likely to have a rising antibody titre when culture positive. Copyright © 2016 Elsevier Ltd. All rights reserved.

Production of succinic acid from sugarcane molasses supplemented with a mixture of corn steep liquor powder and peanut meal as nitrogen sources by Actinobacillus succinogenes.

Science.gov (United States)

Shen, N; Qin, Y; Wang, Q; Liao, S; Zhu, J; Zhu, Q; Mi, H; Adhikari, B; Wei, Y; Huang, R

2015-06-01

The potential of using corn steep liquor powder (CSLP), peanut meal (PM), soybean meal (SM), cotton meal (CM) and urea as the substitute of yeast extract (YE) as the nitrogen source was investigated for producing succinic acid (SA). Actinobacillus succinogenes GXAS137 was used as the fermenting bacterium and sugarcane molasses was used as the main substrate. None of these materials were able to produce SA as high as YE did. The CSLP could still be considered as a feasible and inexpensive alternate for YE as the yield of SA produced using CSLP was second only to the yield of SA obtained by YE. The use of CSLP-PM mixed formulation (CSLP to PM ratio = 2·6) as nitrogen source produced SA up to 59·2 g l(-1) with a productivity of 1·2 g l(-1) h(-1). A batch fermentation using a stirred bioreactor produced up to 60·7 g l(-1) of SA at the same formulation. Fed-batch fermentation that minimized the substrate inhibition produced 64·7 g l(-1) SA. These results suggest that sugarcane molasses supplemented with a mixture of CSLP and PM as the nitrogen source could be used to produce SA more economically using A. succinogenes. Significance and impact of the study: Succinic acid (SA) is commonly used as a platform chemical to produce a number of high value derivatives. Yeast extract (YE) is used as a nitrogen source to produce SA. The high cost of YE is currently the limiting factor for industrial production of SA. This study reports the use of a mixture of corn steep liquor powder (CSLP) and peanut meal (PM) as an inexpensive nitrogen source to substitute YE. The results showed that this CSLP-PM mixed formulation can be used as an effective and economic nitrogen source for the production of SA. © 2015 The Society for Applied Microbiology.

High-temperature thermoelectric properties of AgxYyCa2⋅8Co4O9 ...

Indian Academy of Sciences (India)

Administrator

and thermal conductivity were measured from 303 to 973 K. It was found that the samples contain nanostruc- tured Ag phase ... to that of Lu-doped Ca3Co4O9 + δ (Nong et al 2011). ... ture, large particle sizes, limited degree of chemical homo-.

Borassodendron (Palmae) in the Southeast Asian fossil pollen record

NARCIS (Netherlands)

Maloney, B.K.

2000-01-01

Borassodendron machadonis pollen occurred throughout the Holocene pollen record of Nong Thale Song Hong, Thailand, until about 4000 BP. It was also present in one sample from Khok Phanom Di, Thailand, and in the Mahakam Delta, Kalimantan, records, but B. machadonis has not been reported from the

Dermatology in Ghana: a retrospective review of skin disease at the Korle Bu Teaching Hospital Dermatology Clinic.

Science.gov (United States)

Rosenbaum, Brooke E; Klein, Rebecca; Hagan, Paa Gyasi; Seadey, Mark-Young; Quarcoo, Naa Larteley; Hoffmann, Rachel; Robinson, Maria; Lartey, Margaret; Leger, Marie C

2017-01-01

Ghana is currently developing its provision of dermatology services. Epidemiologic studies of the skin diseases seen by Ghanaian dermatologists are needed to guide these efforts. We aimed to describe the skin conditions seen by and management practices of Ghanaian dermatologists in a specialized clinic. We conducted a chart review of new patients presenting to the Korle Bu Teaching Hospital dermatology clinic during 2014. Among the 529 patients studied, 700 discrete diagnoses were made. The most commonly diagnosed skin conditions were infections (24.6%) and dermatitis (24.6%); atopic dermatitis (8.4%), acne vulgaris (5.3%) and scabies (5.1%) were the most common specific diagnoses. Among infants, children, and adolescents, the most common diagnosis was atopic dermatitis (31.7%, 30.0%, and 14.9%, respectively). Acne vulgaris (12.0%) was the most common skin condition diagnosed in young adults. Irritant contact dermatitis (6.9%) was most common among adults. Lichen planus (9.9%) was the most commonly diagnosed skin condition in the senior population. Diagnoses made by dermatologists differed from the referral diagnosis documented by primary care providers for 65.8% of patients. The most frequently recommended treatments were antihistamines (47.8%) and topical steroids (38.4%). Only 18 diagnostic biopsies were performed. Our study summarizes the skin diseases seen and management practices of Ghanaian dermatologists in a specialized clinic at a large public teaching hospital. The results of this study can help to guide future dermatology education and development efforts in Ghana.

glim ti signifi n e of hGr nd IQgGIPg r tios in srish o k ellulose

Indian Academy of Sciences (India)

long hronology were rried outD overing period of IPQ ye rs @IVTIEEIWVQ eFhFA with S ye r resolution so s to ... developedF pirstlyD the ristle one pine @ inus rist t nd inus long ... dust into the str tosphere nd onsequently ools the. tmosphereD ...

Conhecimento e uso do ouricuri (Syagrus coronata e do babaçu (Orbignya phalerata em Buíque, PE, Brasil Knowledge and use of ouricuri (Syagrus coronata and babaçu (Orbignya phalerata in Buíque, Pernambuco State, Brazil

Directory of Open Access Journals (Sweden)

Márcio Ulisses de Lima Rufino

2008-12-01

Full Text Available O Nordeste do Brasil abriga 80 espécies de palmeiras nativas, com baixo endemismo (27,5%, algumas delas ameaçadas pelas alterações destrutivas do habitat natural, associadas à exploração desordenada. Investigou-se do ponto de vista etnobotânico a importância do ouricuri (Syagrus coronata e do babaçu (Orbignya phalerata em uma comunidade estabelecida junto ao Parque Nacional Vale do Catimbau, município de Buíque, Pernambuco. A importância atribuída pelo povo local para essas espécies foi analisada sob os seguintes aspectos: número de usos, número de informantes que faziam uso de seus produtos diretos ou indiretos; grau de consenso entre os informantes referentes aos usos relatados. Os dados foram obtidos através de entrevistas semi-estruturadas (60 informantes e de índices baseados em técnicas de consenso do informante. Foram citadas sete categorias de uso: alimento do homem; alimento de animais domésticos; alimento de animais silvestres; construção; artesanato; combustível; medicinal. Apesar da diversidade de usos (Sc = 33; Oph = 25, a importância das duas espécies está relacionada predominantemente ao aproveitamento da amêndoa, como mostram os índices de valor para frutos (Sc = 0,48; Oph = 0,56. Analisando a contribuição de cada espécie para o uso total, o ouricuri apresentou maior valor (8,58 em relação ao babaçu (6,31. Sinais de um processo de erosão do conhecimento foram observados, com vários usos apontados como não mais praticados na comunidade, particularmente os associados ao artesanato.The palm tree flora of Brazilian Northeast includes 80 native species, with a low level of endemism (27.5%, some of them threatened by the destructive alterations of the natural habitat, associated to disordered exploration. This study investigated the importance of the ouricuri (Syagrus coronata and the babaçu (Orbignya phalerata in a community established near the Catimbau Valley National Park, Buíque municipality

New metal-organic polygons involving MM quadruple bonds: M8(O2CtBu)4(mu-SC4H2-3,4-{CO2}2)6 (M=Mo, W).

Science.gov (United States)

Byrnes, Matthew J; Chisholm, Malcolm H; Patmore, Nathan J

2005-12-12

The reactions between M2(O2CtBu)4, where M=Mo or W, and thienyl-3,4-dicarboxylic acid (0.5-1.5 equiv) in toluene proceed via a series of detectable intermediates to the compounds M8(O2CtBu)4(mu-SC4H2-3,4-{CO2}2)6, which are isolated as air-sensitive yellow (M=Mo) or red (M=W) powders and show parent molecular ions in their mass spectra (MALDI). The structure of the molybdenum complex was determined by single-crystal X-ray crystallography and shown to contain an unusual M8 polygon involving four Mo2 quadruply bonded units linked via the agency of the six 3,4-thienylcarboxylate groups. The structure has crystallographically imposed S4 symmetry and may be described in terms of a highly distorted tetrahedron of Mo2 units or a bisphenoid in which two Mo2 units are linked by a thienyldicarboxylate such that intramolecular Mo2...O bonding is present, while the other thienylcarboxylate bridges merely serve to link these two [Mo2]...[Mo2] units together. The color of the compounds arises from intense M2 delta-to-thienyl pi transitions and, in THF, the complexes are redox-active and show four successive quasi-reversible oxidation waves. The [M8]+ radical cations, generated by one-electron oxidation with AgPF6, are shown to be valence-trapped (class II) by UV-vis-near-IR and electron paramagnetic resonance spectroscopy. These results are supported by the electronic structure calculations on model compounds M8(O2CH)4(mu-SC4H2-3,4-{CO}2)6 employing density functional theory that reveal only a small splitting of the M2 delta manifold via mixing with the 3,4-thienylcarboxylate pi system.

3D stratigraphic forward modelling of Shu'aiba Platform stratigraphy in the Bu Hasa Field, Abu Dhabi, United Arab Emirates.

Science.gov (United States)

Hu, J.; Lokier, S. W.

2012-04-01

This paper presents the results of three dimensional sequence stratigraphic forward modelling of the Aptian age Shu'aiba Formation from Abu Dhabi, United Arab Emirates (UAE). The Shu'aiba Formation lies within the uppermost part of the Lower Cretaceous Thamama Group and forms one of the most prolific hydrocarbon reservoir intervals of the Middle East with production dating back to the 1960's. The Shu'aiba Formation developed as a series of laterally-extensive shallow-water carbonate platforms in an epeiric sea that extended over the northern margin of the African-Arabian Plate. This shallow sea was bounded by the Arabian Shield to the west and the passive margin with the Neo-Tethys Ocean towards the north and east (Droste, 2010). The exposed Arabian Shield acted as a source of siliciclastic sediments to westernmost regions, however, more offshore areas were dominated by shallow-water carbonate deposition. Carbonate production was variously dominated by Lithocodium-Baccinella, orbitolinid foraminifera and rudist bivalves depending on local conditions. While there have been numerous studies of this important stratigraphic interval (for examples see van Buchem et al., 2010), there has been little attempt to simulate the sequence stratigraphic development of the formation. During the present study modelling was undertaken utilising the CARBONATE-3D stratigraphic forward modelling software (Warrlich et al., 2008; Warrlich et al., 2002)) thus allowing for the control of a diverse range of internal and external parameters on carbonate sequence development. This study focuses on platform development in the onshore Bu Hasa Field - the first giant oilfield to produce from the Shu'aiba Formation in Abu Dhabi. The carbonates of the Bu Hasa field were deposited on the southwest slope of the intra-shelf Bab Basin, siliciclastic content is minor. Initially these carbonates were algal dominated with rudist mounds becoming increasingly important over time (Alsharhan, 1987

DNA methylation and genetic diversity analysis of genus Cycas in ...

African Journals Online (AJOL)

mallory

2012-01-12

Jan 12, 2012 ... elucidate the role of epigenetics in the genetic diversity of these plants. MATERIALS AND METHODS. Plant materials and DNA extraction. 66 Cycas samples consisting of 10 species and one subspecies were collected from the Nong Nooch Tropical Garden, Chonburi province, Thailand. For each species ...

Korean Percussion Ensemble ("Samulnori") in the General Music Classroom

Science.gov (United States)

Kang, Sangmi; Yoo, Hyesoo

2016-01-01

This article introduces "samulnori" (Korean percussion ensemble), its cultural background, and instructional methods as parts of a classroom approach to teaching upper-level general music. We introduce five of eight sections from "youngnam nong-ak" (a style of samulnori) as a repertoire for teaching Korean percussion music to…

Yeast eIF4B binds to the head of the 40S ribosomal subunit and promotes mRNA recruitment through its N-terminal and internal repeat domains.

Science.gov (United States)

Walker, Sarah E; Zhou, Fujun; Mitchell, Sarah F; Larson, Victoria S; Valasek, Leos; Hinnebusch, Alan G; Lorsch, Jon R

2013-02-01

Eukaryotic translation initiation factor (eIF)4B stimulates recruitment of mRNA to the 43S ribosomal pre-initiation complex (PIC). Yeast eIF4B (yeIF4B), shown previously to bind single-stranded (ss) RNA, consists of an N-terminal domain (NTD), predicted to be unstructured in solution; an RNA-recognition motif (RRM); an unusual domain comprised of seven imperfect repeats of 26 amino acids; and a C-terminal domain. Although the mechanism of yeIF4B action has remained obscure, most models have suggested central roles for its RRM and ssRNA-binding activity. We have dissected the functions of yeIF4B's domains and show that the RRM and its ssRNA-binding activity are dispensable in vitro and in vivo. Instead, our data indicate that the 7-repeats and NTD are the most critical domains, which mediate binding of yeIF4B to the head of the 40S ribosomal subunit via interaction with Rps20. This interaction induces structural changes in the ribosome's mRNA entry channel that could facilitate mRNA loading. We also show that yeIF4B strongly promotes productive interaction of eIF4A with the 43S•mRNA PIC in a manner required for efficient mRNA recruitment.

Abant Gölü’ündeki Su Samurunun (Lutra lutra habitat tercihi

Directory of Open Access Journals (Sweden)

İlhami TURAN

2016-01-01

Full Text Available Bu çalışmanın kapsamı Abant Gölü’ndeki Su samurunun habitat tercihlerinin ortaya çıkarılmasıdır. Türkiye’de yayılış gösteren Su samuru (Lutra lutra Linnaeus, 1758, IUCN Kırmızı Liste’ye göre NT (Yakın Tehdit kategorisindedir. Dünyada yayılış gösterdiği bütün ülkelerde koruma altındadır. Koruma çalışmalarının başarıya ulaşabilmesi için tür hakkındaki bilgilerin yeterli düzeyde olması gerekmektedir. Su samurunun habitat tercihlerinin ortaya çıkarılması amacı ile Abant Gölü ile gölü çevreleyen yol arasındaki riparian alanlarda türün kullandığı habitatlar araştırılmıştır. Göl ve kenarındaki sazlık ve çalılık habitatları diğer alanlardan daha fazla tercih ettiği saptanmıştır.

Fièvre bilieuse hémoglobinurique (FBH) de révélation tardive: à ...

African Journals Online (AJOL)

Fièvre bilieuse hémoglobinurique (FBH) de révélation tardive: à propos d'un cas au CHU de Dakar. Aliou Thiongane, Aliou Abdoulaye Ndongo, Papa Moctar Faye, Assane Sylla, Younoussa Kéïta, Djibril Boiro, Idrissa Basse, Ndèye Ramatoulaye Diagne Guèye, Ousmane Ndiaye ...

Cancer risk assessment of patients undergoing computed tomography examination at the Korle-Bu Teaching Hospital (KBTH)

International Nuclear Information System (INIS)

Sackey, T.A.

2015-07-01

The aim of this study is to estimate the effective dose and assess the lifetime attributable risk of cancer incidence of patients undergoing computed tomography scan at the korle-bu Teaching Hospital. Data on volume CT dose index (CTDI vol) and dose length product (DLP ) displayed on the scanner control console was recorded after confirmation of the results by performing independent checks on a phantom. The effective doses were estimated using the displayed and the anatomic region specific conversion factors (K ). The average effective dose for the head, abdomen, chest, neck, and pelvis were 3.63± 2.39mSv, 15.37±8.49 mSv, 12.72 ± 13.97 mSv, 4.04 ± 1.47 mSv and 15.8 ± 3.59 mSv respectively. Effective doses for the head and neck were within the typical range of (1-10mSv) for CT examinations whilst abdomen, chest and pelvis were above 10mSv. The average life attributable risk of cancer incidence for each region of examination were determined from the effective dose, sex and age using the model proposed in BEIR VII report . The average cancer risk incidence for head, neck, chest, abdomen and pelvis examinations were low in the range 1 in 10,000 to 1 in 1,000. There were wide variations in the effective dose values obtained for the same region under examination. This trend calls for the optimization of CT examination protocols to be established to ensure that patient doses are as low as reasonably achievable, economic and social factors being taken into account. (author)

Differentiation between serological responses to Brucella suis and Yersinia enterocolitica serotype O : 9 after natural or experimental infection in pigs

DEFF Research Database (Denmark)

Jungersen, Gregers; Sørensen, Vibeke; Giese, Steen Bjørck

2006-01-01

with responses of B. suis biovar 2-inoculated pigs. FPSR were limited to 2-9 weeks post-YeO:9 inoculation, while B. suis-infected pigs were test-positive throughout the 21-week period of investigation. Although YeO:9-inoculated pigs exhibited FPSR in Brucella tests for a limited period of time, the serological...

Regulering, ikke kriminalisering

DEFF Research Database (Denmark)

Ludvigsen, Stian Skår; Sieberg, Katri K.

2007-01-01

Kriminalisering av horekunder vil føre til at markedet for seksuelle tjenester skyves inn i det skjulte.  Skjer dette, kan kostnadene bli høye.......Kriminalisering av horekunder vil føre til at markedet for seksuelle tjenester skyves inn i det skjulte.  Skjer dette, kan kostnadene bli høye....

Re-evaluation of the shielding adequacy of the brachytherapy treatment room at Korle-Bu teaching hospital, Ghana

International Nuclear Information System (INIS)

Arwui, C. C.

2009-06-01

Staff and the general public's safety during the operation of the 137 Cs brachytherapy unit at the Korle Bu teaching hospital depends on the adequacy of the shielding of the facility. Shielding design of the brachytherapy unit at the hospital was based on postulated workload and postulated occupancy factors to critical locations at the facility where the public and staff may occupy. This facility has been in existence for the past twelve (12) years and has accumulated operational workload data which differs from the postulated one. A study was carried out to re-evaluate the integrity of the biological shielding of the 137 Cs brachytherapy unit. This study analyzed the accumulated workload data and used the information to perform shielding calculations to verify the adequacy of the biological shielding thicknesses to provide sufficient protection of staff and the public. Dose rate calculations were verified by measurements with calibrated dose rate meters. This provided the basis for determining the current state of protection and safety for staff and the general public. The results show that despite the variation in actual and postulated workloads, the dose rates were below the reference values of 0.5μSv/h for public areas and 7.5μSv/h for controlled areas. It was confirmed that the present shielding thickness of 535 mm can accommodate a high dose rate (HDR) 192 Ir source with activity in the range 370 - 570 GBq with an operational workload of 30 patients per week and an average treatment time of 10 minutes.

Pollen grains in quaternary sediments from the Campos Basin, state of Rio de Janeiro, Brazil: Core BU-91-GL-05

Directory of Open Access Journals (Sweden)

Aline Gonçalves de Freitas

2013-12-01

Full Text Available Here, we describe pollen grains extracted from a Pleistocene-Holocene sediment core (BU-91-GL-05; 22°48'45"S; 41°54'13"W taken from the Albacora Slope (22°48'45"S; 41°54'13"W, located in the Campos Basin of the northern region of the state of Rio de Janeiro, Brazil. The analysis resulted in the identification and morphological description of 46 types of pollen: one of a gymnosperm genus (Podocarpus; and 45 of angiosperm taxa across 27 families-one family of monocotyledons (Poaceae and 26 families (30 types of dicotyledons. The most common angiosperm families were Amaranthaceae (Chenopodium, Amaranthus and Gomphrena; Fabaceae (Fabaceae type, Bauhinia, Inga and Canavalia; Malpighiaceae (Tetrapteris, Heteropteris and Peixotoa; Malvaceae (Sida, Abutilon, Hibiscus and Pseudobombax; Rubiaceae (Faramea, Borreria and Psychotria; Asteraceae (Eupatorium and tribe Vernonieae; Bignoniaceae (Bignoniaceae type, Adenocalymma and Tabebuia; and Onagraceae (Fuchsia and Ludwigia. The palynoflora in this study are associated with dense montane and submontane Atlantic Forest, semideciduous forest and restinga (coastal woodland, all of which are present in the state of Rio de Janeiro. Palynological analysis can provide important data about paleovegetation and paleoclimatic changes in the studied area during the Quaternary, specifically in the last 145,000 years.

Stable long-term pulmonary function after fludarabine, antithymocyte globulin and i.v. BU for reduced-intensity conditioning allogeneic SCT.

Science.gov (United States)

Dirou, S; Malard, F; Chambellan, A; Chevallier, P; Germaud, P; Guillaume, T; Delaunay, J; Moreau, P; Delasalle, B; Lemarchand, P; Mohty, M

2014-05-01

Lung function decline is a well-recognized complication following allogeneic SCT (allo-SCT). Reduced-intensity conditioning (RIC) and in vivo T-cell depletion by administration of antithymocyte globulin (ATG) may have a protective role in the occurrence of late pulmonary complications. This retrospective study reported the evolution of lung function parameters within the first 2 years after allo-SCT in a population receiving the same RIC regimen that included fludarabine and i.v. BU in combination with low-dose ATG. The median follow-up was 35.2 months. With a median age of 59 years at the time of transplant, at 2 years, the cumulative incidences of non-relapse mortality was as low as 9.7%. The cumulative incidence of relapse was 33%. At 2 years, the cumulative incidences of extensive chronic GVHD (cGVHD) and of pulmonary cGVHD were 23.1% and 1.9%, respectively. The cumulative incidences of airflow obstruction and restrictive pattern were 3.8% and 9.6%, respectively. Moreover, forced expiratory volume (FEV1), forced vital capacity (FVC) and FEV1/FVC ratio remained stable from baseline up to 2 years post transplantation (P=0.26, P=0.27 and P=0.07, respectively). These results correspond favorably with the results obtained with other RIC regimens not incorporating ATG, and suggest that ATG may have a protective pulmonary role after allo-SCT.

Stemcell Information: SKIP000586 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ... Lei Ye Lei Ye Division of Cardiology, Department of Medicine, University of Mi...nnesota Medical School, Minneapolis, Minnesota, United States of America ... Division of Cardiology, Department... of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, United States of America ... Division of Cardiology...l, Minneapolis, Minnesota, United States of America ... Division of Cardiology, Department of Medicine, Univers

The potential application of a transcriptionally regulated oncolytic herpes simplex virus for human cancer therapy

Science.gov (United States)

Miao, L; Fraefel, C; Sia, K C; Newman, J P; Mohamed-Bashir, S A; Ng, W H; Lam, P Y P

2014-01-01

Background: Emerging studies have shown the potential benefit of arming oncolytic viruses with therapeutic genes. However, most of these therapeutic genes are placed under the regulation of ubiquitous viral promoters. Our goal is to generate a safer yet potent oncolytic herpes simplex virus type-1 (HSV-1) for cancer therapy. Methods: Using bacterial artificial chromosome (BAC) recombineering, a cell cycle-regulatable luciferase transgene cassette was replaced with the infected cell protein 6 (ICP6) coding region (encoded for UL39 or large subunit of ribonucleotide reductase) of the HSV-1 genome. These recombinant viruses, YE-PC8, were further tested for its proliferation-dependent luciferase gene expression. Results: The ability of YE-PC8 to confer proliferation-dependent transgene expression was demonstrated by injecting similar amount of viruses into the tumour-bearing region of the brain and the contralateral normal brain parenchyma of the same mouse. The results showed enhanced levels of luciferase activities in the tumour region but not in the normal brain parenchyma. Similar findings were observed in YE-PC8-infected short-term human brain patient-derived glioma cells compared with normal human astrocytes. intratumoural injection of YE-PC8 viruses resulted in 77% and 80% of tumour regression in human glioma and human hepatocellular carcinoma xenografts, respectively. Conclusion: YE-PC8 viruses confer tumour selectivity in proliferating cells and may be developed further as a feasible approach to treat human cancers. PMID:24196790

Stemcell Information: SKIP000588 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ... Lei Ye Lei Ye Division of Cardiology, Department of Medicine, University of M...innesota Medical School, Minneapolis, Minnesota, United States of America ... Division of Cardiology, Departmen...t of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, United States of America ... Division of Cardiology...ol, Minneapolis, Minnesota, United States of America ... Division of Cardiology, Department of Medicine, Univer

Stemcell Information: SKIP000584 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ... Lei Ye Lei Ye Division of Cardiology, Department of Medicine, University o...f Minnesota Medical School, Minneapolis, Minnesota, United States of America ... Division of Cardiology, Depart...ment of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, United States of America ... Division of Cardiology...chool, Minneapolis, Minnesota, United States of America ... Division of Cardiology, Department of Medicine, Uni

Effects of supported (nBuCp)2ZrCl2 catalyst active center multiplicity on crystallization kinetics of ethylene homo- and copolymers

KAUST Repository

Atiqullah, Muhammad

2014-07-01

Two different supported zirconocene, that is, bis(n-butylcyclopentadienyl) zirconium dichloride (nBuCp)2ZrCl2, catalysts were synthesized. Each catalyst was used to prepare one ethylene homopolymer and one ethylene-1-hexene copolymer. Catalyst active center multiplicity and polymer crystallization kinetics were modeled. Five separate active center types were predicted, which matched the successive self-nucleation and annealing (SSA) peak temperatures. The predicted crystallinity well matched the differential scanning calorimetric (DSC) values for a single Avrami-Erofeev index, which ranged between 2 and 3 for the polymers experimented. The estimated apparent crystallization activation energy Ea did not vary with cooling rates, relative crystallinity α, and crystallization time or temperature. Therefore, the concept of variable/instantaneous activation energy was not found to hold. Ea linearly increased with the weight average lamellar thickness Lwav DSC-GT; and for each homopolymer, it exceeded that of the corresponding copolymer. Higher Ea, hence slower crystallization, was identified as a pre-requisite to attain higher crystallinity. Crystallization parameters were correlated to polymer backbone parameters, which are influenced by catalyst active center multiplicity. © 2013 Taiwan Institute of Chemical Engineers.

Management of radiation dose to paediatric patients undergoing CT examination at Korle-bu Teaching Hospital, Accra-Ghana

International Nuclear Information System (INIS)

Gedel, A.M.

2010-01-01

In this work management of paediatric patients doses for Computed Tomography examinations have been studied at Korle-Bu Teaching Hospital. The assessment of the management system involved: evaluation of the frequency of examinations, comparison of techniques factors used for adult and children; estimation of CTDI w , CTDI vol , DLP and effective dose; evaluation of quality assurance and quality control programmes to optimise paediatric patient doses. The frequency of CT examinations for paediatric patients accounted for 1300 out 5200 examinations (25%) of the total examinations recorded for the year 2008 which is five times that of the East European countries, indicating an overuse of CT examinations for children not taking into account paediatric patient anatomy and the section of the body being scanned. Adult CT exposure parameters such as the KV, mAs, scan length, pitch, and collimation values were being used in paediatric CT examination. Effective dose estimated for children were higher than that for adults by factors 5.1, 1.8, 3.1 and 3.9 more for head, chest, abdomen and pelvis examinations respectively. From the questionnaire administered and dosimetry results there was no established justification policy, procedures and referral criteria for CT examination requests for children. There was no Quality Assurance Committee to see to the implementation of dose management system dedicated to paediatrics patients. There was the need for the Hospital Authorities to formulate policies in the training of CT equipment operators, radiographers and radiographers and radiologist in modern CT technology as well as in the selection of appropriate parameters tailored to individual patient size that can achieve desirable diagnostic image quality at low doses. (au)

Selection and evaluation of soybean lines derived from gamma irradiation for rust resistance

International Nuclear Information System (INIS)

Smutkupt, S.; Wongpiyasatid, A.; Lamseejan, S.

1983-01-01

In 1979, seeds of 11 soybean cultivars were gamma irradiated with 15 and 30 krad. Treated and control seeds of each cultivar were planted in the rainy season. In the rainy season of 1980, M 3 populations were screened for rust resistance in Nong Hoi Valley and Mae Joe Experiment Station, both in Chiang Main province. The IWGSR rust rating system was used. Based upon the slow growth of rust on soybean plants, 6 and 115 plants were selected from 2,802 control plants and from 28,824 treated plants, respectively. Selected lines were evaluated in Nong Hoi Valley in the rainy season of 1981. Sixteen selections with average good seed yield per plant and low percentage of shrivelled seeds were obtained. Among them, two lines, namely G8586/Line number 81-1-072 and S.J. 4/Line number 81-1-037 gave the higher average seed yield per plant than other lines. They are at present in a preliminary yield trial in Chiang Mai. Chiang Mai. (author)

Radionuclide Tc-99m MDP Imaging for diagnosis of bone tumour at Korle-Bu Teaching Hospital (Ghana): an illustrative review

International Nuclear Information System (INIS)

Hasford, F.; Sosu, E.K.; Nani, K.; Sackey, T.A.; Boadu, M.; Wilson, I.K.; Addison, E.C.K.; Amuasi, J.H.

2010-01-01

Radioisotopes are used in diagnosing primary and metastatic bone tumours because of the high sensitivity. Diagnosing bone tumours using technetium methylene diphosphonate (Tc-99m MDP) on 9 randomly selected whole-body bone scans have been demonstrated by clinical studies of patients for illustrative review. Upon satisfactory testing of the e.cam (R) Single Photon Emission Computed Tomography at the Nuclear Medicine Department (Korle-Bu Teaching Hospital), scans of patients provided essential physiologic information about the sites of bone lesions and prognosis as shown by sequential changes in tracer uptake. The bone scintigrams were classified either as normal or pathologic. Of the 197 patients (91 males and 106 females) who underwent radioactive whole-body scans in the year 2006, the peak age at bone tumour detection was between 51 and 60 years. From qualitative analyses of the reported cases, 144 patients were diagnosed with bone tumours, but ∼ 17 % were found to be primary, while ∼ 83 % were metastatic in nature. The observation confirmed other published data that bone tumours with origin in the cells of bone are not prevalent compared to tumours that metastasize from other parts of the body, such as breast, cervix and prostate. Breast, prostate and cervical cancers contributed respectively to 34 %, 19 % and 18 % of the bone tumour cases, but only 3 % were diagnosed with osteoporosis (a relatively rare type of bone disease). (au)

A Comparative Study of the Story Events in Literary and Cinematic Narrative: A Comparison between the Story of Ashghalduni (Dustbin and the Adapted Movie, Dayere-ye Mina (The Cycle

Directory of Open Access Journals (Sweden)

Z. Hayati

2016-07-01

Full Text Available The present article tries to study the story Ašghālduni (Dustbin by Gholāmhossein Sā’edi and the adapted movie Dāyere-ye Minā (The Cycle by Dāryuš Mehrjuyi with a view to new adaptation theories. Of course, these theories have not yet been consistent and well-established; but its literature is going to evolve, especially its essentials are discussed in the study method of narratology. As an example, this proposition is discussed in theoretical subjects of adaptation that even in the loyal adapted movies, in which the structure of the literary story and the sequence of events in the movie are preserved, some of the semantic functions change because of story entry into the cinematic discourse along with the needs of medium of cinema. For example, the figurative aspect of Sā’edi's story in its adapted movie has been influenced by the scheme and sometimes realism dominates symbolism. Mehrjuyi has organized the events in the discourse of classic cinema in order to encourage the reader to persist the events during a certain time period. The way of timing a movie in terms of a three-screen structure encourages the spectator to follow the events and causes the "scheme" to dominate the "idea". Since the dominance of either scheme or idea creates different themes, it can be said that the very structural change leads somewhat to semantic change. Similarly, the change of Sā’edi's open ending narrative to a close one prevents the audience to participate in re-making the fictional fate of Ali; the sort that exists in a literary text.

ZiBuPiYin recipe protects db/db mice from diabetes-associated cognitive decline through improving multiple pathological changes.

Directory of Open Access Journals (Sweden)

Jing Chen

Full Text Available Multiple organ systems, including the brain, which undergoes changes that may increase the risk of cognitive decline, are adversely affected by diabetes mellitus (DM. Here, we demonstrate that type 2 diabetes mellitus (T2DM db/db mice exhibited hippocampus-dependent memory impairment, which might associate with a reduction in dendritic spine density in the pyramidal neurons of brain, Aβ1-42 deposition in the prefrontal cortex (PFC and hippocampus, and a decreased expression of neurostructural proteins including microtubule-associated protein (MAP2, a marker of dendrites, and postsynaptic density 95 (PSD95, a marker of excitatory synapses. To investigate the effects of the ZiBuPiYin recipe (ZBPYR, a traditional Chinese medicine recipe, on diabetes-related cognitive decline (DACD, db/db mice received daily administration of ZBPYR over an experimental period of 6 weeks. We then confirmed that ZBPYR rescued learning and memory performance impairments, reversed dendritic spine loss, reduced Aβ1-42 deposition and restored the expression levels of MAP2 and PSD95. The present study also revealed that ZBPYR strengthened brain leptin and insulin signaling and inhibited GSK3β overactivity, which may be the potential mechanism or underlying targets of ZBPYR. These findings conclude that ZBPYR prevents DACD, most likely by improving dendritic spine density and attenuating brain leptin and insulin signaling pathway injury. Our findings provide further evidence for the effects of ZBPYR on DACD.

Peyniraltı Suyundan Yoğurt Eldesi

Directory of Open Access Journals (Sweden)

Gülen Çiftçi

2015-02-01

Full Text Available Peynir üretiminde organik yükü yüksek olan ve peyniraltı suyu adı verilen yeşilimsi-sarı renkte bir atık ortaya çıkmaktadır. Türkiye’de yılda yaklaşık olarak 7.784.000 ton peyniraltı suyu üretilmektedir. Bu çalışmanın amacı peyniraltı suyuna yağsız süt tozu katarak Türk mutfağında yüksek gıda değeri nedeniyle yaygın bir yere sahip olan yoğurt elde etmektir. Yoğurt eldesi sırasında Lactobacillus bulgaricus ve Streptococcus thermophilus kültürleri kullanılmıştır. Çalışmada kullanılan asidik peyniraltı suyu Topçuoğlu fabrikasından temin edilmiştir. Tatlı peyniraltı suyu ise laboratuvarda pastörize sütten üretilmiştir. Hem yağsız süttozu hem de aşı %6 oranlarında peyniraltı sularına katılmıştır. İnkübasyon 44 oC’de bir saat devam etmiştir. Topçuoğlu peyniraltı suyundan üretilen yoğurdun süt yağı %0.03, yağsız katı madde miktarı %9.844 ve titre edilebilir asitlik değeri %0.0286’dır. Laboratuvarda üretilen peyniraltı suyundan yapılan yoğurtta ise bu değerler sırasıyla %0.4, %12.123 ve %0.0239’dur. Her iki tip yoğurdun peroksidaz testlerinin negatif, Koliform ve E. coli bakterilerinin olmadığı, küf ve maya sayımının yüzden fazla olduğu tespit edilmiştir.

A codon window in mRNA downstream of the initiation codon where NGG codons give strongly reduced gene expression in Escherichia coli

DEFF Research Database (Denmark)

Gonzalez de Valdivia, Ernesto I; Isaksson, Leif A

2004-01-01

and GGG, but not GGN or GNG (where N is non-G), are unique since they are associated with a very low gene expression also if located at positions +2, +3 and +5. All codons, including NGG, give a normal gene expression if placed at positions +7. The negative effect by the NGG codons is true for both...

Rusçuklu Zarîfî Ömer Baba ve Manzum-Mensur Tasavvuf Terimleri Lügatçesi: Istılahât-ı Meşâyıh Zarîfî Omar Baba From Ruscuk and His Glossary Of Verse-Prose Sufi Terminology: Istilahât-i Mashayikh

Directory of Open Access Journals (Sweden)

Turgut KOÇOĞLU

2012-09-01

�ncelediğimiz biyografik kaynaklarda Zarîfî Ömer Baba ile ilgili fazla bilgi bulunmamaktadır. Kaynakların belirttiğine göre bugünkü Bulgaristan sınırlarına dahil Rusçuk kasabasından olan Zarîfî Ömer Baba, Sa'diyye tarikatına intisap etmiş ve bu tarikatta şeyhlik makamına kadar yükselmiştir. Zarîfî’nin tezkirelerde adı geçen 2 eseri vardır. Bunlar, Pend-nâme ve Divân'dır. Ancak yaptığımız katalog taramalarında ona âit olduğu belirtilen 7 eser daha tespit edilmiştir. Bu eserler: Tasavvuf-nâme, İsm-i A’zam, Kitâb-ı İ'tikâd, Hikâye-yi Kan Kalesi, Beyân-ı Ser-encâm, Kısasu’l-Enbiyâ ve Istılahât-ı Meşâyıh'dır. İnceleyebildiğimiz kadarıyla Zarîfî'nin eserleri, din-tasavvuf ve ahlak içeriklidir. Onun, kaynaklarda bahsedilmeyen eserlerinden Istılahât-ı Meşâyıh, bir çeşit tasavvuf terimleri sözlüğüdür. Dînî ve tasavvufî bazı konuların anlatıldığı 23 beyitlik manzum bir bölümle başlayan bu eserde, toplam 70 tasavvufî terim açıklanmıştır. Istılahât-ı Meşayıh'da izah edilen bu terimleri, isimler ve makamlar olarak ikiye ayırmak mümkündür. Eserde isimler ve alametleri mensur, makamlar ise manzum şekilde kaleme alınmıştır. Yazar, önce kendi tasavvuf ekseninde bir insanın sahip olduğu vasıfları ve özellikleri belirten bir ismi mensur olarak izah etmiş sonra bu ismin özelliklerini taşıyan kişinin bulunacağı manevî makamı manzum olarak dile getirmiştir. Bu yazıda ana hatlarıyla Zarîfî’nin hayatı, edebî kişiliği ve eserleri incelenmiş; Istılahât-ı Meşayıh'ın dili, üslubu ve muhtevası üzerine bir inceleme yapılmıştır. Ayrıca bu eserdeki birkaç kavram, aynı tasavvuf terimlerine yüklenen anlamların tarikatlara, meşreblere belki zamana ve mekana göre farklılık arz ettiğini göstermek amacıyla başka tasavvuf terimleri sözlükleriyle mukayese edilmiştir. Son olarak Istılahât-ı Meşâyıh’ın metni mevcut 2 nüshasından hareketle g

Stemcell Information: SKIP000587 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available ... Yes Quantitative RT-PCR ... Yes ... Lei Ye Lei Ye Division of Cardiology,...Minnesota, United States of America ... Division of Cardiology, Department of Medici...ne, University of Minnesota Medical School, Minneapolis, Minnesota, United States of America ... Division of Cardiology... Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, United States of America ... Division of Cardio...logy, Department of Medicine, University of Minnesota Medical School, Minneapolis,

Stemcell Information: SKIP000585 [SKIP Stemcell Database[Archive

Lifescience Database Archive (English)

Full Text Available istry Study Yes Cardiac Myocyte Differentiation ... No ... No ... Lei Ye Lei Ye Division of Cardiology...sota, United States of America Division of Cardiology, Department of Medicine, University of Minnesota Medic...al School, Minneapolis, Minnesota, United States of America Division of Cardiology...iology, Department of Medicine, University of Minnesota Medical School, Minneapolis..., Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, United States of America ... Division of Card

Cationic rare-earth metal SALEN complexes.

Science.gov (United States)

Liu, Qiancai; Meermann, Christian; Görlitzer, Hans W; Runte, Oliver; Herdtweck, Eberhardt; Sirsch, Peter; Törnroos, Karl W; Anwander, Reiner

2008-11-28

Complexes (Salpren(tBu,tBu))Y[N(SiHMe2)2](thf) and (SALEN(tBu,tBu))La[N(SiHMe2)2](thf) (SALEN(tBu,tBu) = Salcyc(tBu,tBu) and Salpren(tBu,tBu)) were prepared from Ln[N(SiHMe2)2]3(thf)2 and H2SALEN(tBu,tBu). The yttrium complex was characterized by X-ray crystallography revealing intrinsic solid-state structural features: the metal centre is displaced by 1.05 angstroms from the [N2O2] least squares plane of a highly bent Salpren(tBu,tBu) ligand (angle(Ph,Ph) dihedral angle of 80.4(1) degrees ) and is coordinated asymmetrically by the silylamide ligand exhibiting one significant Y---(HSi) beta-agostic interaction (Y-N1-Si1, 106.90(9) degrees; Y---Si1, 3.2317(6) angstroms). Complexes (SALEN(tBu,tBu))Ln[N(SiHMe2)2](thf)n (n = 1, Sc; n = 2, Y, La) react with ammonium tetraphenylborate to form the ion pairs [(SALEN(tBu,tBu))Ln(thf)n][BPh4]. The cationisation was proven by X-ray crystal structure analyses of [(Salpren(tBu,tBu))Sc(thf)2][B(C6H5)4].2(thf) and [(Salpren(tBu,tBu))Ln(thf)3][B(C6H5)4].4(thf) (Ln = Y, La), showing an octahedral and pentagonal-bipyramidal coordination geometry, respectively.

Türkiye’de Finansal Gelişme ve Ekonomik Büyüme İlişkisinin Nedensellik Analizi

Directory of Open Access Journals (Sweden)

Mehmet Zeki AK

2016-07-01

Full Text Available Türkiye ekonomisi için büyüme ve finansal gelişme arasındaki nedensellik ilişkisinin yönünü tespit etmeyi amaçlayan bu çalışmada 1989-2011 dönemine ait yıllık veriler kullanılarak Toda-Yamamoto testi uygulanmıştır. Ayrıca, temel bileşenler analizi yöntemi ile Türkiye ekonomisinin özgün koşullarını yansıtan ve finansal gelişmişlik düzeyini en kapsamlı biçiminde ölçmeyi mümkün kılacak bir finansal gelişme endeksi oluşturulmuştur. Ampirik bulgular, ‘89 sonrası dönemde ağırlıklı olarak ‘büyüme’den ‘finansal gelişme’ye doğru işleyen tek yönlü nedensellik ilişkisi söz konusu olduğunu ortaya koymaktadır. Bir başka ifadeyle finansal gelişme ve ekonomik büyüme arasında ‘talep takipli’ bir nedensellik ilişkisi söz konusudur.

Turismo, cooperação e desenvolvimento local em Unidades de Conservação: o caso do Parque Nacional do Catimbau, Buíque – PE

Directory of Open Access Journals (Sweden)

Josilene Henriques da Silva

2013-01-01

Full Text Available The creation of protected areas can bring socio-economic development to the places where they were created. Particularly through tourism, it may generate some benefits such as incomes and the con- servation. Therefore, the way the community is structured to foster these benefits can lead to social change processes. In this context, we sought to analyze the cooperative relations between social actors, like the Buíque (Pernambuco, Brazil residents, to promote tourism in the Catimbau National Park, consi- dering the local development concept. This research was developed over a specialization course, and it is a qualitative study case, which includes literature review and field research with application of interviews. Therefore, it was found that, despite the existence of some ‘cooperative’ interactions, not all agents parti- cipate in this process. So, among other things discussed, it is believed that the Catimbau National Park might contribute to local development in future.

Impact of Neutrino Flavor Oscillations on the Neutrino-driven Wind Nucleosynthesis of an Electron-capture Supernova

Science.gov (United States)

Pllumbi, Else; Tamborra, Irene; Wanajo, Shinya; Janka, Hans-Thomas; Hüdepohl, Lorenz

2015-08-01

Neutrino oscillations, especially to light sterile states, can affect nucleosynthesis yields because of their possible feedback effect on the electron fraction (Ye). For the first time, we perform nucleosynthesis calculations for neutrino-driven wind trajectories from the neutrino-cooling phase of an 8.8 {M}⊙ electron-capture supernova (SN), whose hydrodynamic evolution was computed in spherical symmetry with sophisticated neutrino transport and whose Ye evolution was post-processed by including neutrino oscillations between both active and active-sterile flavors. We also take into account the α-effect as well as weak magnetism and recoil corrections in the neutrino absorption and emission processes. We observe effects on the Ye evolution that depend in a subtle way on the relative radial positions of the sterile Mikheyev-Smirnov-Wolfenstein resonances, on collective flavor transformations, and on the formation of α particles. For the adopted SN progenitor, we find that neutrino oscillations, also to a sterile state with eV mass, do not significantly affect the element formation and in particular cannot make the post-explosion wind outflow neutron-rich enough to activate a strong r-process. Our conclusions become even more robust when, in order to mimic equation-of-state-dependent corrections due to nucleon potential effects in the dense-medium neutrino opacities, six cases with reduced Ye in the wind are considered. In these cases, despite the conversion of active neutrinos to sterile neutrinos, Ye increases or is not significantly lowered compared to the values obtained without oscillations and active flavor transformations. This is a consequence of a complicated interplay between sterile-neutrino production, neutrino-neutrino interactions, and α-effect.

Yersinia enterocolitica and Photorhabdus asymbiotica β-lactamases BlaA are exported by the twin-arginine translocation pathway.

Science.gov (United States)

Schriefer, Eva-Maria; Hoffmann-Thoms, Stephanie; Schmid, Franz X; Schmid, Annika; Heesemann, Jürgen

2013-01-01

In general, β-lactamases of medically important Gram-negative bacteria are Sec-dependently translocated into the periplasm. In contrast, β-lactamases of Mycobacteria spp. (BlaC, BlaS) and the Gram-negative environmental bacteria Stenotrophomonas maltophilia (L2) and Xanthomonas campestris (Bla(XCC-1)) have been reported to be secreted by the twin-arginine translocation (Tat) system. Yersinia enterocolitica carries 2 distinct β-lactamase genes (blaA and blaB) encoding BlaA(Ye) and the AmpC-like β-lactamase BlaB, respectively. By using the software PRED-TAT for prediction and discrimination of Sec from Tat signal peptides, we identified a functional Tat signal sequence for Yersinia BlaA(Ye). The Tat-dependent translocation of BlaA(Ye) could be clearly demonstrated by using a Y. enterocolitica tatC-mutant and cell fractionation. Moreover, we could demonstrate a unique unusual temperature-dependent activity profile of BlaA(Ye) ranging from 15 to 60 °C and a high 'melting temperature' (T(M)=44.3°) in comparison to the related Sec-dependent β-lactamase TEM-1 (20-50°C, T(M)=34.9 °C). Strikingly, the blaA gene of Y. enterocolitica is present in diverse environmental Yersinia spp. and a blaA homolog gene could be identified in the closely related Photorhabdus asymbiotica (BlaA(Pa); 69% identity to BlaA(Ye)). For BlaA(Pa) of P. asymbiotica, we could also demonstrate Tat-dependent secretion. These results suggest that Yersinia BlaA-related β-lactamases may be the prototype of a large Tat-dependent β-lactamase family, which originated from environmental bacteria. Copyright © 2012 Elsevier GmbH. All rights reserved.

Enhancement of methyl tert-butyl ether degradation by the addition of readily metabolizable organic substrates

International Nuclear Information System (INIS)

Chen Dongzhi; Chen Jianmeng; Zhong Weihong

2009-01-01

Supplements with readily metabolizable organic substrates were investigated to increase the biomass and enhance degradation of methyl tert-butyl ether (MTBE) due to the low biomass yield of MTBE which has been one of the factors for low-rate MTBE degradation. The influence of various organic substrates on the rate of aerobic degradation of methyl tert-butyl ether (MTBE) by Methylibium petroleiphilum PM1 was investigated, and only yeast extract (YE), beef extract and tryptone exhibited stimulatory effect. With the concentration of each substrate being 100 mg/L, the average MTBE removal rate could increase to 1.29, 1.20 and 1.04 mg/(L h), respectively, in comparison with 0.71 mg/(L h) when carried out in medium without addition. The stimulatory effects of YE addition, as well as induction period required by MTBE degradation, varied dramatically with the storage conditions, pre-culture medium and concentrations of the inoculums. The extent of stimulatory effects of YE might be closely related to the proportion of induction period in the total time of MTBE-degradation. The removal efficiency increased from about 50% to 90.5% with the addition of YE in a packed-bed reactor loaded with calcium alginate immobilized cells.

Effects on grape amino acid concentration through foliar application of three different elicitors.

Science.gov (United States)

Gutiérrez-Gamboa, G; Portu, J; Santamaría, P; López, R; Garde-Cerdán, T

2017-09-01

Elicitors play an important role in the defense against pathogens as an alternative to chemical pesticides by increasing secondary metabolites. Their effect on grape amino acid has been little investigated. Thus, the aim of this research was to study the influence of methyl jasmonate (MeJ), chitosan (CHT), and a yeast extract (YE) on grape amino acid composition, through foliar applications to grapevines. The must amino acid concentration was analyzed by HPLC. The results showed that CHT and YE treatments decreased the must concentration of several amino acids, affecting total amino acid content (from 2364 to 1961, and 1818mg/L, respectively). However, MeJ treatment had a slight effect on grape amino acid content, increasing the concentration of Met (from 8.95 to 12.13mg/L) and Phe (from 7.96 to 9.29mg/L). It seems to be that, the resistance induction through CHT and YE treatments results in physiological costs to grapevines associated with a decrease on grape amino acid concentration. Consequently, MeJ applications, as a viticultural practice, could be a better tool than CHT and YE treatments, because did not affect grape amino acid concentration. Copyright © 2017 Elsevier Ltd. All rights reserved.

Factors associated with gastro-duodenal disease in patients undergoing upper GI endoscopy at the Korle-Bu Teaching Hospital, Accra, Ghana.

Science.gov (United States)

Archampong, Timothy N A; Asmah, Richard H; Wiredu, Edwin K; Gyasi, Richard K; Nkrumah, Kofi N

2016-06-01

There is a high prevalence of gastro-duodenal disease in sub-Saharan Africa. Peptic ulcer disease in dyspeptic patients, 24.5%, was comparable to prevalence of gastro-duodenal disease among symptomatic individuals in developed countries (12 - 25%). Limited data exists regarding its associated risk factors despite accumulating evidence indicating that gastroduodenal disease is common in Ghana. This study investigates risk factors associated with gastro-duodenal disease at the Korle-Bu Teaching Hospital, Accra, Ghana. This study utilized a cross-sectional design to consecutively recruit patients referred with upper gastro-intestinal symptoms for endoscopy. The study questionnaire was administered to study participants. Helicobacter pylori infection was confirmed by rapid-urease examination at endoscopy. Of 242 patients sampled; 64 had duodenal ulcer, 66 gastric ulcer, 27gastric cancer and 64 non-ulcer dyspepsia. Nineteen (19) had duodenal and gastric ulcer while 2 had gastric ulcer and cancer. A third (32.6%) of patients had history of NSAID-use. H. pyloriwas associated with gastric ulcer (p=0.033) and duodenal ulcer (p=0.001). There was an increased prevalence of duodenal ulcer in H. pylori-infected patients taking NSAIDs, P=0.003. H. pylori was a major risk factor for peptic ulcer disease. However, NSAID-related gastro-duodenal injury has been shown to be common in H. pylori infected patients. It highlights the need for awareness of the adverse gastro-intestinal effects in a H. pylori endemic area.

Synthesis and Electronic Structure of Dissymmetrical, Naphthalene-Bridged Sandwich Complexes [Cp ' Fe(mu-C10H8)MCp*](x) (x=0,+1; M = Fe, Ru; Cp ' = eta(5)-C5H2-1,2,4-tBu(3); Cp* = eta(5)-C5Me5)

NARCIS (Netherlands)

Malberg, J.; Lupton, E.; Schnöckelborg, E.M.; de Bruin, B.; de Sutter, J.; Meyer, K.; Hartl, F.; Wolf, R.

2013-01-01

The dissymmetrical naphthalene-bridged complexes [Cp'Fe(mu-C10H8)FeCp*] (3; Cp* = eta(5)-C5Me5, Cp' = eta(5)-C5H2-1,2,4-tBu(3)) and [Cp'Fe(mu-C10H8)RuCp*] (4) were synthesized via a one-pot procedure from FeCl2(thf)(1.5), Cp'K, KC10H8, and [Cp*FeCl(tmeda)] (tmeda =

The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation

DEFF Research Database (Denmark)

Cogoi, Susanna; Ferino, Annalisa; Miglietta, Giulia

2018-01-01

KRAS is one of the most mutated genes in human cancer. It is controlled by a G4 motif located upstream of the transcription start site. In this paper, we demonstrate that 8-oxoguanine (8-oxoG), being more abundant in G4 than in non-G4 regions, is a new player in the regulation of this oncogene. W...

Clinical and Molecular Characteristics of Human Rotavirus G8P[8] Outbreak Strain, Japan, 2014.

Science.gov (United States)

Kondo, Kenji; Tsugawa, Takeshi; Ono, Mayumi; Ohara, Toshio; Fujibayashi, Shinsuke; Tahara, Yasuo; Kubo, Noriaki; Nakata, Shuji; Higashidate, Yoshihito; Fujii, Yoshiki; Katayama, Kazuhiko; Yoto, Yuko; Tsutsumi, Hiroyuki

2017-06-01

During March-July 2014, rotavirus G8P[8] emerged as the predominant cause of rotavirus gastroenteritis among children in Hokkaido Prefecture, Japan. Clinical characteristics were similar for infections caused by G8 and non-G8 strains. Sequence and phylogenetic analyses suggest the strains were generated by multiple reassortment events between DS-1-like P[8] strains and bovine strains from Asia.

Fıtrat Hadisi’nin Osmanlı'nın Devşirme Sisteminde Hayata Aksedişi 'The Hadith of Fitrah’ And How It Is Reflected On Life Ottoman’s Devshirme System

Directory of Open Access Journals (Sweden)

Mustafa IŞIK

2013-07-01

-culture on thisevent with together ‘Devshirme’. ‘Her çocuk, fıtrat üzere doğar; sonra onu ana-babası Yahudileştirir, Hıristiyanlaştırır veya Mecusîleştirir’ hadisi, temel İslam bilimlerinde ‘fıtrat hadisi’ olarak bilinir. İslami literatürde, geçmişten günümüze, bu hadis hakkında çeşitli görüşler ortaya konmuştur. Fıtrat hadisinin, klasik hadis literatüründeki kaynakları ve hadis imamlarının bu hadise bakışları açısından daha çok ‘Çocuğun ölmesi halinde dinî ve hukukî durumunun ne olacağı?’ sorusu üzerinde durulmuştur. Ancak hadis bilginleri ve bazı interdisipliner İslam âlimleri, fıtrat’ın ‘insanlığın ortak dinî temeli’ olduğuna inanmaktadırlar. Bu görüşe bağlı olarak biz, fıtrat hadisi’nin Osmanlı’daki ‘devşirme’ hadisesiyle örtüştüğünü düşünüyoruz. Devşirme sisteminin, tarihi bir olgu olarak, Osmanlı’da gerçekleşen halini ele almak istiyoruz. Bu haliyle Osmanlı Devleti bu olguyu sistemleştirip kanun, tüzük ve yönetmeliği olan bir sistem haline koymadan önce dini yönünü hesaba kattığını; bu hadisteki ‘fıtrat gerçeği’nden hareket etmiş olabileceğini; güçlü kaslar ve çalışkan beyinler sayesinde özelde devletine genelde insanlığa hizmet ettiğini var sayıyoruz. O günün dünya devleti olan Osmanlı’dan bugünün dünya devleti ABD’ye baktığımızda, işleyiş ve yöntem farklı olsa da, birtakım paralellikler görmekteyiz. Farklı asırlarda, değişik coğrafyalarda, birbirine benzemeyen iki büyük medeniyetin ortaya koyduğu uygulamadaki benzerlik ve ulaştığı ortak nokta, eğitimin, başat belirleyici olduğu gerçeğidir. Bu makalenin amacı, sadece tarihî bir fenomeni dile getirmek değil; fıtratın anlamını, geçerliliğini bu tarihî olgudan hareketle yinelemektir. Makalemizde bu konuyu fıtrat yani insanın değişmeyen varlık yapısı ve eğitim-kültürün bu yapıya etkisini ‘devşirme’ olgusuyla

Bibliography of Soviet Laser Developments Number 54, July-August 1981.

Science.gov (United States)

1982-12-01

as a continuing effort to document current Soviet-bloc developments in the quantum electronics field. The period covered is July-August 1981, and...Theory 20. Gershenzon, Ye.M., V.M. Kalygina, B.I. Levit , and B.N. Tumanov (464). Relaxation ogcillation resonance in autodyne oscillators. IVUZ...7Ye446) 189. Stapor, A., 3. Langer, T. Langer, and B. Krukowska-Fulde(NS). Efficient two- and three- quantum conversion of IR radiation to the visible in

Tlhalošontši ya mongwalo: Go ngwala seo se sa tšweletšego ...

African Journals Online (AJOL)

Bontši bja baithuti ba maleme a Bathobaso ga bo tšee mongwalo go ba ye nngwe ya dithutwana tše bohlokwa tša maleme. Ka fao barutwana le batho ba bangwe ba go kgona go bala le go ngwala ga ba sa na le taba le thutwana ye ya mongwalo. Seo se dira gore go be le mabošaedi a mmalwa go akaretšwa a mopeleto, ...

Fungi detoxification study from pistachio by non-ionizing irradiation; Barrasi-ye estefadeh az parto'ha-ye gheyr-e yonsaz dar gharchzoda-i-ye pesteh

Energy Technology Data Exchange (ETDEWEB)

Ghafourian, H; Sadighzadeh, A; Dabbagh, R

1998-07-01

4,6 and 10 minutes of microwaves exposure provides and effective and relatively rapid sterilization for different purposes in medicine and food industries for example sterilization of materials which have been contaminated with Aspergillus flavus (Pcc-5004) and Aspergillus parasiticus (Pcc-5018) which are producer of Aflatoxin especially on pistachios and other dried fruits. Microwaves exposure induces a morphological modification of the cells and germicidal effects of ultrasonic waves has been attributed to gaseous cavitation. There was a significant reduction in fungal growth compared with those under the control which decreased growth with increased microwave and ultrasound exposure time.

OXIDATIVE ALKYLATION OF (ETA-5-C5ME5)2TIR (R=CL, ME, ET, CH=CH2, PH, OME, N=C(H)TERT-BU) TO (ETA-5-C5ME5)2TI(ME)R BY GROUP-12 ORGANOMETALLIC COMPOUNDS MME2

NARCIS (Netherlands)

LUINSTRA, GA; TEUBEN, JH

1991-01-01

Oxidative alkylation of Cp*2TiX (Cp*: eta-5-C5Me5; X = OMe, Cl, N = C(H)tBu) and Cp*2TiMe by CdMe2 or ZnMe2 gives diamagnetic Cp*2Ti(Me)X and Cp*2TiMe2 respectively, and cadmium or zinc. The reactions of Cp*2TiR (R = Et, CH = CH2, Ph) with MMe2 (M = Cd, Zn) give statistical mixtures of Cp*2Ti(Me)R,

Studies on the separation of {sup 89}Sr(II) from irradiated yttria target using 4, 4{sup '}(5{sup '}) di-tert-butyl-cyclohexano-18-crown-6 (DtBuCH18C6) by solvent extraction technique

Energy Technology Data Exchange (ETDEWEB)

Saha, Debasish; Vithya, Jayagopal; Kumar, Ramalingam; Venkata Subramani, Canchipuram Ramamoorthy; Vasudeva Rao, Polur Ranga [Indira Gandhi Centre for Atomic Research (IGCAR), Kalpakkam (India). Chemistry Group

2016-07-01

The radioisotope {sup 89}Sr as {sup 89}SrCl{sub 2} is medically useful for bone pain palliation and is produced in fast reactors using the {sup 89}Y(n, p){sup 89}Sr reaction. A procedure for isolation of the radionuclide {sup 89}Sr by chemical processing of the irradiated Y{sub 2}O{sub 3} target has been standardised and trial runs have been carried out at the Fast Breeder Test Reactor (FBTR), Kalpakkam. The chemical processing of the irradiated Y{sub 2}O{sub 3} target involves (i) the removal of target Y(III) by TBP extraction and (ii) further purification of the separated {sup 89}Sr fraction by cationic exchange chromatography. However a selective isolation of {sup 89}Sr by the Sr-specific crown ether makes the above chemical processing faster and relatively simple. This work presents a study on the selective removal of Sr from the irradiated target dissolver solution using the Sr-specific crown ether 4,4{sup '}(5{sup '}) di-tert-butyl-cyclohexano-18-crown-6 (DtBuCH18C6) in octanol medium. The separation behaviour of the other impurities such as Ce(IV), Y(III), Tb(III), Eu(III), Zn(II), Mn(II) and Rb(I) present along with Sr(II) in the irradiated sample was also investigated. The method of separation by using the crown ether DtBuCH18C6 is proved to be a potential tool for the purification of {sup 89}Sr(II) source produced from yttria target in fast reactors.

Different coordination modes for disulfoxides towards diorganotin(IV) dichlorides. X-ray crystal structures of 1,2-cis-bis-(phenylsulfinyl)ethene (rac-,cis-cbpse) and adducts [{l_brace}Ph{sub 2}SnCl{sub 2}(meso-bpse){r_brace}{sub n}] and [{l_brace}n-Bu{sub 2}SnCl{sub 2}(pdtd){r_brace}{sub 2}

Energy Technology Data Exchange (ETDEWEB)

Sousa, Gerimario F. de [Universidade de Brasilia (UnB), DF (Brazil). Inst. de Quimica], e-mail: gfreitas@unb.br; Ellena, Javier [Universidade de Sao Paulo (USP), Sao Carlos, SP (Brazil). Inst. de Fisica; Malta, Valeria R.S. [Universidade Federal de Alagoas (UFAL), Maceio, AL (Brazil). Dept. de Quimica e Biotecnologia; Ardisson, Jose D. [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil). Lab. de Fisica Aplicada

2009-07-01

The reactions of meso-1,2-bis(phenylsulfinyl)ethane (meso-bpse) with Ph{sub 2}SnCl{sub 2}, 2-phenyl-1,3-dithiane trans-1-trans-3-dioxide (pdtd) with n-Bu{sub 2}SnCl{sub 2} and 1,2-cis-bis-(phenylsulfinyl) ethene (rac-,cis-cbpse) with Ph{sub 2}SnCl{sub 2}, in 1:1 molar ratio, yielded [{l_brace}Ph{sub 2}SnCl{sub 2}(meso-bpse){r_brace}{sub n}], [{l_brace}n-Bu{sub 2}SnCl{sub 2}(pdtd){r_brace}{sub 2}] and [{l_brace}Ph{sub 2}SnCl{sub 2}(rac,cis-cbpse){r_brace}x] (x = 2 or n), respectively. All adducts were studied by IR, Moessbauer and {sup 119}Sn NMR spectroscopic methods, elemental analysis and single crystal X-ray diffractometry. The X-ray crystal structure of [{l_brace}Ph{sub 2}SnCl{sub 2}(meso-bpse){r_brace}{sub n}] revealed the occurrence of infinite chains in which the tin(IV) atoms appear in a distorted octahedral geometry with Cl atoms in cis and Ph groups in trans positions. The X-ray crystal structure of [{l_brace}n-Bu{sub 2}SnCl{sub 2}(pdtd){r_brace}{sub 2}] revealed discrete centrosymmetric dimeric species in which the tin(IV) atoms possess a distorted octahedral geometry with bridging disulfoxides in cis and n-butyl moieties in trans positions. The spectroscopic data indicated that the adduct containing the rac,cis-cbpse ligand can be dimeric or polymeric. The X-ray structural analysis of the free rac-,cis-cbpse sulfoxide revealed that the crystals belong to the C2/c space group. (author)

Magnetic measurements of glass from Tikal, Guatemala: Possible tektites

Science.gov (United States)

Senftle, F. E.; Thorpe, A. N.; Grant, J. R.; Hildebrand, A.; Moholy-Nagy, H.; Evans, B. J.; May, L.

2000-08-01

Certain glass nodules found at the archeological site at Tikal, Guatemala, have been considered as possible tektites. To test this possibility, magnetic studies have been made on three of the glass specimens. These specimens are similar to tektites, both visually and also because they contain very little Fe3+ as detected by Mössbauer spectroscopy. The magnetic Curie constants are similar in magnitude to those found for normal tektites but show some variation from point to point in the same specimen. This variation reflects an inhomogeneity in the iron concentration. The Fe2+ calculated from the Curie constants accounts for most of the iron. The temperature-independent component of the total dc magnetic susceptibility is several times higher than that found in tektites from other strewn fields. The high values can be explained if the glass contains metallic iron spherules with Fe in the parts per million range and/or a ferromagnetic component which does not saturate in a low magnetic field. The magnetic properties resemble those of Muong Nong type tektites and suggest that the Tikal glass specimens are tektites of the Muong Nong type.

Adding to Yersinia enterocolitica Gene Pool Diversity: Two Cryptic Plasmids from a Biotype 1A Isolate

Directory of Open Access Journals (Sweden)

Daniela Lepka

2009-01-01

Full Text Available We report the nucleotide sequence of two novel cryptic plasmids (4357 and 14 662 base pairs carried by a Yersinia enterocolitica biotype 1A strain isolated from pork. As distinguished from most biotype 1A strains, this isolate, designated 07-04449, exhibited adherence to eukaryotic cells. The smaller plasmid pYe4449-1 carries five attributable open reading frames (ORFs encoding the first CcdA/CcdB-like antitoxin/toxin system described for a Yersinia plasmid, a RepA-like replication initiation protein, and mobilizing factors MobA and MobC. The deduced amino acid sequences showed highest similarity to proteins described in Salmonella (CcdA/B, Klebsiella (RepA, and Plesiomonas (MobA/C indicating genomic fluidity among members of the Enterobacteriaceae. One additional ORF with unknown function, termed ORF5, was identified with an ancestry distinct from the rest of the plasmid. While the C+G content of ORF5 is 38.3%, the rest of pYe4449-1 shows a C+G content of 55.7%. The C+G content of the larger plasmid pYe4449-2 (54.9% was similar to that of pYe4449-1 (53.7% and differed from that of the Y. enterocolitica genome (47.3%. Of the 14 ORFs identified on pYe4449-2, only six ORFs showed significant similarity to database entries. For three of these ORFs likely functions could be ascribed: a TnpR-like resolvase and a phage replication protein, localized each on a low C+G island, and DNA primase TraC. Two ORFs of pYe4449-2, ORF3 and ORF7, seem to encode secretable proteins. Epitope-tagging of ORF3 revealed protein expression at 4°C but not at or above 27°C suggesting adaptation to a habitat outside swine. The hypothetical protein encoded by ORF7 is the member of a novel repeat protein family sharing the DxxGN(xnDxxGN motif. Our findings illustrate the exceptional gene pool diversity within the species Y. enterocolitica driven by horizontal gene transfer events.

Song Bu Li Decoction, a Traditional Uyghur Medicine, Protects Cell Death by Regulation of Oxidative Stress and Differentiation in Cultured PC12 Cells

Directory of Open Access Journals (Sweden)

Maitinuer Maiwulanjiang

2013-01-01

Full Text Available Song Bu Li decoction (SBL is a traditional Uyghur medicinal herbal preparation, containing Nardostachyos Radix et Rhizoma. Recently, SBL is being used to treat neurological disorders (insomnia and neurasthenia and heart disorders (arrhythmia and palpitation. Although this herbal extract has been used for many years, there is no scientific basis about its effectiveness. Here, we aimed to evaluate the protective and differentiating activities of SBL in cultured PC12 cells. The pretreatment of SBL protected the cell against tBHP-induced cell death in a dose-dependent manner. In parallel, SBL suppressed intracellular reactive oxygen species (ROS formation. The transcriptional activity of antioxidant response element (ARE, as well as the key antioxidative stress proteins, was induced in dose-dependent manner by SBL in the cultures. In cultured PC12 cells, the expression of neurofilament, a protein marker for neuronal differentiation, was markedly induced by applied herbal extract. Moreover, the nerve growth factor- (NGF- induced neurite outgrowth in cultured PC12 cells was significantly potentiated by the cotreatment of SBL. In accord, the expression of neurofilament was increased in the treatment of SBL. These results therefore suggested a possible role of SBL by its effect on neuron differentiation and protection against oxidative stress.

2790-IJBCS-Article-Lambienou YE

African Journals Online (AJOL)

hp

Cette étude a porté sur les sols et la végétation herbacée d'une savane pâturée au Burkina Faso. Elle ... does not impact soil chemical and biological parameters, except for soil basal respiration that increases .... Hyparrhenia subplumosa,.

JPRS Report, Science & Technology, USSR: Science & Technology Policy

Science.gov (United States)

1990-05-31

information science, and found money for a children’s rehabilitation center and a children’s outpa- tient clinic; it purchased medicines for the victims...Yu.V. Muravyev, S.K. Sokolov, A.P. Alyabyev. "The Development of New Methods and Systems of the Therapy of Rheumatic Diseases." Recommended by...Institute of Irrigated Horticulture . 24. Ye.A. Osipova, M.P. Mingova, G.A. Loginova, Ye.S. Sharova, V.V. Prilepov. "The Development of the Nevskiy

Mutation and screening of high-alcoholic-yield yeast by HEPE and optimization of the fermentation condition

International Nuclear Information System (INIS)

Han Jingjing; Lu Jiangtao; Zhang Qin; Wang Yan; Fu Yujie; Wang Shilong; Fu Haiying

2011-01-01

The Saccharomyces Cerevisiae YE0 was mutated using high-energy-pulse-electron (HEPE) beam. After ethanol stress and determination of the alcohol yield by gas chromatograph, the mutant YF1 with high alcoholic yield was obtained. The results showed that under the optimized fermentation conditions (34 degree C as the fermentation temperature, 72 h as the fermentation time and 30% as the glucose concentration), the alcoholic yield of YF1 was 15.57% which was 58.23% higher than that of the original strain YE0 (9.84%) under the same conditions. The growth rate and lethal temperature of the mutant YF1 were obviously enhanced to the original strain YE0. The mutant YF1 has a great potential application in industrial production of alcohol. And it can also be used as the original strain for further mutagenesis to get the strain of higher alcoholic yield. (authors)

Depletion of dendritic cells enhances innate anti-bacterial host defense through modulation of phagocyte homeostasis.

Directory of Open Access Journals (Sweden)

Stella E Autenrieth

2012-02-01

Full Text Available Dendritic cells (DCs as professional antigen-presenting cells play an important role in the initiation and modulation of the adaptive immune response. However, their role in the innate immune response against bacterial infections is not completely defined. Here we have analyzed the role of DCs and their impact on the innate anti-bacterial host defense in an experimental infection model of Yersinia enterocolitica (Ye. We used CD11c-diphtheria toxin (DT mice to deplete DCs prior to severe infection with Ye. DC depletion significantly increased animal survival after Ye infection. The bacterial load in the spleen of DC-depleted mice was significantly lower than that of control mice throughout the infection. DC depletion was accompanied by an increase in the serum levels of CXCL1, G-CSF, IL-1α, and CCL2 and an increase in the numbers of splenic phagocytes. Functionally, splenocytes from DC-depleted mice exhibited an increased bacterial killing capacity compared to splenocytes from control mice. Cellular studies further showed that this was due to an increased production of reactive oxygen species (ROS by neutrophils. Adoptive transfer of neutrophils from DC-depleted mice into control mice prior to Ye infection reduced the bacterial load to the level of Ye-infected DC-depleted mice, suggesting that the increased number of phagocytes with additional ROS production account for the decreased bacterial load. Furthermore, after incubation with serum from DC-depleted mice splenocytes from control mice increased their bacterial killing capacity, most likely due to enhanced ROS production by neutrophils, indicating that serum factors from DC-depleted mice account for this effect. In summary, we could show that DC depletion triggers phagocyte accumulation in the spleen and enhances their anti-bacterial killing capacity upon bacterial infection.

Identification and classification of genes regulated by phosphatidylinositol 3-kinase- and TRKB-mediated signalling pathways during neuronal differentiation in two subtypes of the human neuroblastoma cell line SH-SY5Y.

Science.gov (United States)

Nishida, Yuichiro; Adati, Naoki; Ozawa, Ritsuko; Maeda, Aasami; Sakaki, Yoshiyuki; Takeda, Tadayuki

2008-10-28

SH-SY5Y cells exhibit a neuronal phenotype when treated with all-trans retinoic acid (RA), but the molecular mechanism of activation in the signalling pathway mediated by phosphatidylinositol 3-kinase (PI3K) is unclear. To investigate this mechanism, we compared the gene expression profiles in SK-N-SH cells and two subtypes of SH-SY5Y cells (SH-SY5Y-A and SH-SY5Y-E), each of which show a different phenotype during RA-mediated differentiation. SH-SY5Y-A cells differentiated in the presence of RA, whereas RA-treated SH-SY5Y-E cells required additional treatment with brain-derived neurotrophic factor (BDNF) for full differentiation. After exposing cells to a PI3K inhibitor, LY294002, we identified 386 genes and categorised these genes into two clusters dependent on the PI3K signalling pathway during RA-mediated differentiation in SH-SY5Y-A cells. Transcriptional regulation of the gene cluster, including 158 neural genes, was greatly reduced in SK-N-SH cells and partially impaired in SH-SY5Y-E cells, which is consistent with a defect in the neuronal phenotype of these cells. Additional stimulation with BDNF induced a set of neural genes that were down-regulated in RA-treated SH-SY5Y-E cells but were abundant in differentiated SH-SY5Y-A cells. We identified gene clusters controlled by PI3K- and TRKB-mediated signalling pathways during the differentiation of two subtypes of SH-SY5Y cells. The TRKB-mediated bypass pathway compensates for impaired neural function generated by defects in several signalling pathways, including PI3K in SH-SY5Y-E cells. Our expression profiling data will be useful for further elucidation of the signal transduction-transcriptional network involving PI3K or TRKB.

Yersinia enterocolitica targets cells of the innate and adaptive immune system by injection of Yops in a mouse infection model.

Directory of Open Access Journals (Sweden)

Martin Köberle

2009-08-01

Full Text Available Yersinia enterocolitica (Ye evades the immune system of the host by injection of Yersinia outer proteins (Yops via a type three secretion system into host cells. In this study, a reporter system comprising a YopE-beta-lactamase hybrid protein and a fluorescent staining sensitive to beta-lactamase cleavage was used to track Yop injection in cell culture and in an experimental Ye mouse infection model. Experiments with GD25, GD25-beta1A, and HeLa cells demonstrated that beta1-integrins and RhoGTPases play a role for Yop injection. As demonstrated by infection of splenocyte suspensions in vitro, injection of Yops appears to occur randomly into all types of leukocytes. In contrast, upon infection of mice, Yop injection was detected in 13% of F4/80(+, 11% of CD11c(+, 7% of CD49b(+, 5% of Gr1(+ cells, 2.3% of CD19(+, and 2.6% of CD3(+ cells. Taking the different abundance of these cell types in the spleen into account, the highest total number of Yop-injected cells represents B cells, particularly CD19(+CD21(+CD23(+ follicular B cells, followed by neutrophils, dendritic cells, and macrophages, suggesting a distinct cellular tropism of Ye. Yop-injected B cells displayed a significantly increased expression of CD69 compared to non-Yop-injected B cells, indicating activation of these cells by Ye. Infection of IFN-gammaR (receptor- and TNFRp55-deficient mice resulted in increased numbers of Yop-injected spleen cells for yet unknown reasons. The YopE-beta-lactamase hybrid protein reporter system provides new insights into the modulation of host cell and immune responses by Ye Yops.

Influence of Jiang Tang Bu Shen Fang on expression of IKKβ mRNA in diabetic rats%降糖补肾方对糖尿病大鼠IKKβ mRNA表达的影响

Institute of Scientific and Technical Information of China (English)

范冠杰; 孙晓泽; 唐咸玉; 孙璐; 曾星; 罗广波; 卢绮韵; 温建炫

2011-01-01

目的 观察降糖补肾方对小剂量链脲佐菌素(STZ)加高脂饲料诱导的糖尿病模型大鼠肌肉组织IKK激酶β(IKKβ)信使核糖核酸(mRNA)表达的影响.方法 雄性SD大鼠高脂饲料喂养4周后注射小剂量STZ,1周后测大鼠空腹血糖,血糖值>11.1 mmoL/L者为造模成功的大鼠,将造模成功的大鼠随机分为模型组和降糖补肾方干预组,另设阿司匹林对照组和空白对照组,药物干预4周,取大腿肌肉组织,采用聚合酶链反应逆转录RT-PCR技术检测IKKβ mRNA表达水平.结果 模型组IKKβ mRNA表达明显高于空白对照组,是空白对照组的5.098倍(P0.05.结论 降糖补肾方在一定程度上能抑制糖尿病大鼠IKKβ mRNA基因,这可能是降糖补肾方抑制炎症信号通路的传导而发挥其改善胰岛素抵抗治疗糖尿病的机制之一.%Objective To observe the influence of Jiang Tang Bu Shen Fang on the expression of I kappa P kinase (IKKp) mRNA in muscular tissue in diabetic rats induced by low-dose streptozotocin ( STZ) and high-fat diet (HFD). Methods Male SD rats were fed HFD for 4 weeks, and then injected low-dose STZ. After one week the level of fasting plasma glucose was detected in rats and those with higher than 11. 1 mmol/L of level of fasting plasma glucose were successfully modeled. The rats were randomly divided into the model group, low-dose, mid-dose and high-dose Jiang Tang Bu Shen Fang groups (low-dose, mid-dose and high-dose groups), aspirin group and blank group. All groups were intervened by relevant medicinal for 4 weeks. The expression of IKKp mRNA in muscular tissue was detected by using reverse transcription polymerase chain reaction (RT-PCR). Results The expression of IKKp mRNA in the model group was significantly higher than that in the blank group (5.098 times, P 0. 05 compared with that in the model group. Conclusion Jiang Tang Bu Shen Fang can inhibit IKK(3 mRNA to some extent in diabetic rats, which may be one of mechanisms of the

Ethylene homo- and copolymerization chain-transfers: A perspective from supported (n BuCp) 2 ZrCl 2 catalyst active centre distribution

KAUST Repository

Atiqullah, Muhammad

2015-04-01

Polymerization chain termination reactions and unsaturation of the polymer backbone end are related. Therefore, in this study, the parameters resulting from the modelling of the active centre distribution of the supported catalyst - silica/MAO/(nBuCp)2ZrCl2 - were applied to evaluate the active-centre-dependent ethylene homo- and copolymerization rates, as well as the corresponding chain termination rates. This approach, from a microkinetic mechanistic viewpoint, elucidates better the 1-hexene-induced positive comonomer effect and chain transfer phenomenon. The kinetic expressions, developed on the basis of the proposed polymerization mechanisms, illustrate how the active site type-dependent chain transfer phenomenon is influenced by the different apparent termination rate constants and momoner concentrations. The active centre-specific molecular weight M ni (for the above homo- and copolymer), as a function of chain transfer probability, p CTi, varied as follows: log (p C Ti) = log (mwru) - log (Mn i), where mw ru is the molecular weight of the repeat unit. The physical significance of this finding has been explained. The homo- and copolymer backbones showed all the three chain end unsaturations (vinyl, vinylidene, and trans-vinylene). The postulated polymerization mechanisms reveal the underlying polymer chemistry. The results of the present study will contribute to develop in future supported metallocene catalysts that will be useful to synthesize polyethylene precursors having varying chain end unsaturations, which can be eventually used to prepare functional polyethylenes. [Figure not available: see fulltext.] © 2015 Indian Academy of Sciences.

Anionic Polymerization of Styrene and 1,3-Butadiene in the Presence of Phosphazene Superbases

KAUST Repository

Ntetsikas, Konstantinos

2017-10-23

The anionic polymerization of styrene and 1,3-butadiene in the presence of phosphazene bases (t-BuP4, t-BuP2 and t-BuP1), in benzene at room temperature, was studied. When t-BuP1 was used, the polymerization proceeded in a controlled manner, whereas the obtained homopolymers exhibited the desired molecular weights and narrow polydispersity (Ð < 1.05). In the case of t-BuP2, homopolymers with higher than the theoretical molecular weights and relatively low polydispersity were obtained. On the other hand, in the presence of t-BuP4, the polymerization of styrene was uncontrolled due to the high reactivity of the formed carbanion. The kinetic studies from the polymerization of both monomers showed that the reaction rate follows the order of [t-BuP4]/[sec-BuLi] >>> [t-BuP2]/[sec-BuLi] >> [t-BuP1]/[sec-BuLi] > sec-BuLi. Furthermore, the addition of t-BuP2 and t-BuP1 prior the polymerization of 1,3-butadiene allowed the synthesis of polybutadiene with a high 1,2-microstructure (~45 wt %), due to the delocalization of the negative charge. Finally, the one pot synthesis of well-defined polyester-based copolymers [PS-b-PCL and PS-b-PLLA, PS: Polystyrene, PCL: Poly(ε-caprolactone) and PLLA: Poly(L-lactide)], with predictable molecular weights and a narrow molecular weight distribution (Ð < 1.2), was achieved by sequential copolymerization in the presence of t-BuP2 and t-BuP1.

On multi-level thinking and scientific understanding

Science.gov (United States)

McIntyre, Michael Edgeworth

2017-10-01

Professor Duzheng YE's name has been familiar to me ever since my postdoctoral years at MIT with Professors Jule CHARNEY and Norman PHILLIPS, back in the late 1960s. I had the enormous pleasure of meeting Professor YE personally in 1992 in Beijing. His concern to promote the very best science and to use it well, and his thinking on multi-level orderly human activities, reminds me not only of the communication skills we need as scientists but also of the multi-level nature of science itself. Here I want to say something (a) about what science is; (b) about why multi-level thinking—and taking more than one viewpoint—is so important for scientific as well as for other forms of understanding; and (c) about what is meant, at a deep level, by "scientific understanding" and trying to communicate it, not only with lay persons but also across professional disciplines. I hope that Professor YE would approve.

Fibrillation mechanism of a model intrinsically disordered protein revealed by 2D correlation deep UV resonance Raman spectroscopy.

Science.gov (United States)

Sikirzhytski, Vitali; Topilina, Natalya I; Takor, Gaius A; Higashiya, Seiichiro; Welch, John T; Uversky, Vladimir N; Lednev, Igor K

2012-05-14

Understanding of numerous biological functions of intrinsically disordered proteins (IDPs) is of significant interest to modern life science research. A large variety of serious debilitating diseases are associated with the malfunction of IDPs including neurodegenerative disorders and systemic amyloidosis. Here we report on the molecular mechanism of amyloid fibrillation of a model IDP (YE8) using 2D correlation deep UV resonance Raman spectroscopy. YE8 is a genetically engineered polypeptide, which is completely unordered at neutral pH yet exhibits all properties of a fibrillogenic protein at low pH. The very first step of the fibrillation process involves structural rearrangements of YE8 at the global structure level without the detectable appearance of secondary structural elements. The formation of β-sheet species follows the global structural changes and proceeds via the simultaneous formation of turns and β-strands. The kinetic mechanism revealed is an important new contribution to understanding of the general fibrillation mechanism proposed for IDP.

The effect of waaL genes deletion from Yersinia enterocolitica O:3 genome on bacteria LPS’ phenotype

Directory of Open Access Journals (Sweden)

Shevchenko J. I.

2014-11-01

Full Text Available Aim. To estimate WaaL ligase contribution in the lipopolysaccharide (LPS phenotype profile formation of Y. enterocolitica O:3 (YeO3 bacteria. Methods. The waaL-knock-out mutants were created by an allelic exchange strategy. The LPS phenotypes of created mutants were visualized by silver-stained DOC-PAGE and immunoblotting with specific outer core (core oligosaccharide, hexasaccharide, OC and O-polysaccharide (OPS or O-Ag monoclonal antibodies. Results. Deletion of waaLOS gene from YeO3 genome has a marked effect on OC ligation in either single or double mutants. The waaLPS deletion has an opposite effect on the OPS ligation – barely detected increasing of OPS bands. Conclusions. The LPS ligases of YeO3 exhibit relaxed donor substrate specificity. Under given conditions the effect of WaaLOS ligase is more significant for OC and OPS ligation onto lipid A than that of WaaLPS.

Olbaltumvielu un peptīdu sorbcijas īpašību izpēte AEŠH apstākļos uz dažādām C18 kolonnām

OpenAIRE

Marduseviča, Aļona

2014-01-01

Olbaltumvielu un peptīdu sorbcijas īpašību izpēte AEŠH apstākļos uz dažādām C18 kolonnām. A. Marduseviča, darba vadītāji Dr. Chem. Asoc. Prof. P. Mekšs, O. Rotkāja. Maģistra darbs, 51 lappuses, 3 tabulas, 37 attēli, 42 literatūras avoti. Latviešu valodā. Atslēgas vārdi: OLBALUMVIELAS, PEPTĪDI, AEŠH, C18 KOLONNAS, IZDALĪŠANAS FAKTORS, GRADIENTA SLĪPUMS. Darbā apskatīti olbaltumvielu un peptīdu atdalīšanas mehānismi, gradients, organisko šķīdinātāju, kolonnas un temperatūras ietekme uz ol...

Risky Bu$ine$$

Science.gov (United States)

Galuszka, Peter

2006-01-01

Hedge funds are the rock stars of today's financial world. These slightly regulated pools of equity, which are open only to rich players, are managed through secretive and sophisticated investment strategies. Although the risks are high, so are the potential benefits. Despite the risks, many colleges and universities have chosen to invest heavily…

"A/S PET Baltija" kvalitātes pārvaldību sistēmu loma uzņēmuma konkurētspējas nodrošināšanā

OpenAIRE

Goldšteins, Jānis

2012-01-01

Bakalaura darba tēma ir ,,A/S PET Baltija’’ kvalitātes pārvaldību sistēmu loma uzņēmuma konkurētspējas nodrošināšanā. Bakalaura darba mērķis ir izpētīt A/S PET Baltija kvalitātes pārvaldības sistēmu darbības ietekmi uz uzņēmuma konkurētspēju, atklāt problēmas un izstrādāt priekšlikumus problēmu samazināšanai. Bakalaura darbs satur: 65 lapas, 4 tabulas, 24 attēlus. Darba pirmajā daļā autors analizē Eiropas Direktīvu un LR likumdošanas normatīvo aktu analīzi atkritumu apsaimniek...

Strategy iteration is strongly polynomial for 2-player turn-based stochastic games with a constant discount factor

DEFF Research Database (Denmark)

Hansen, Thomas Dueholm; Miltersen, Peter Bro; Zwick, Uri

2011-01-01

Ye showed recently that the simplex method with Dantzig pivoting rule, as well as Howard's policy iteration algorithm, solve discounted Markov decision processes (MDPs), with a constant discount factor, in strongly polynomial time. More precisely, Ye showed that both algorithms terminate after...... iterations. Second, and more importantly, we show that the same bound applies to the number of iterations performed by the strategy iteration (or strategy improvement) algorithm, a generalization of Howard's policy iteration algorithm used for solving 2-player turn-based stochastic games with discounted zero...

Games to get Hegemony in Iranian Politics : Participation of Islamic Jurists after the Revolution

OpenAIRE

Kuroda, Kenji

2009-01-01

After the Iranian Islamic Revolution in 1979, Islamic jurists have played an important role in the political arena of the new establishment. This paper aimed to describe changes in the Shī'ite jurisprudence academia in contemporary Iran, especially after the revolution. Thus I focused on owze-ye 'Elmīye (Shī'ite learning institution) in Qom before and after the revolution. Then I figured out the changes in the educational aspect and the administrative aspect. In addition, I tried to reveal a ...

Metal, bond energy, and ancillary ligand effects on actinide-carbon σ-bond hydrogenolysis. A kinetic and mechanistic study

International Nuclear Information System (INIS)

Lin, Z.; Marks, T.J.

1987-01-01

A kineticmechanistic study of actinide hydrocarbyl ligand hydrogenolysis (An-R + H 2 → An-H + RH) is reported. For the complex Cp' 2 TH(CH 2 -t-Bu)(O-t-Bu)(Cp' = eta 5 -Me 5 C 5 ), the rate law is first-order in organoactinide and first-order in H 2 , with k/sub H2/k/sub D2/ = 2.5 (4) and k/sub THF/k/sub toluene/ = 2.9 (4). For a series of complexes, hydrogenolysis rates span a range of ca. 10 5 with Cp' 2 ThCH 2 C(CH 3 ) 2 CH 2 ≅ Cp' 2 U(CH 2 -t-Bu) (too rapid to measure accurately) > Cp' 2 Th(CH 2 -t-Bu)[OCH(t-Bu) 2 ] = Cp' 2 Th(CH 2 -t-Bu)(O-t-Bu) > Cp' 2 Th(CH 2 -t-Bu)(Cl) > Me 2 Si(Me 4 C 5 ) 2 Th(n-Bu) 2 > Cp' 2 Th(n-Bu) 2 ≅ Cp' 2 ThMe 2 > Cp' 2 Th(Me)(O 3 SCF 3 ) > Cp' 2 Th(n-Bu)[OCG(t-Bu) 2 ] ≅ Cp' 2 Th(Me)[OSiMe 2 (t-Bu)] > Cp' 2 ZrMe 2 = Cp' 2 Th(rho-C 6 H 4 NMe 2 )(O-tu-Bu) > Cp' 2 Th(Ph)(O-t-Bu) > Cp' 2 U(Me)[OCH(t-Bu) 2 ] > Cp' 2 Th(Me)[OCH(t-Bu) 2 ]. In the majority of cases, the rate law is cleanly first-order in organoactinide over 3 or more half-lives. However, for Cp' 2 ThMe 2 → (Cp' 2 ThH 2 ) 2 , an intermediate is observe by NMR that is probably [Cp' 2 Th(Me)(μ-H)] 2 . For Cp' 2 Th(Me)(O 3 SCF 3 ), a follow-up reaction, which consumes Cp' 2 TH(H)(O 3 SCF 3 ) is detected. Variable-temperature kinetic studies yield ΔH** = 3.7 (2) kcalmol and ΔS double dagger = -50.8 (7) eu for Cp' 2 Th(CH 2 -t-Bu)(O-t-Bu) and ΔH double dagger = 9 (2) kcalmol and ΔS double dagger = -45 (5) eu for Cp' 2 U(Me)[OCH(O-t-Bu) 2

Efficacy of a biomechanically-based yoga exercise program in knee osteoarthritis: A randomized controlled trial.

Science.gov (United States)

Kuntz, Alexander B; Chopp-Hurley, Jaclyn N; Brenneman, Elora C; Karampatos, Sarah; Wiebenga, Emily G; Adachi, Jonathan D; Noseworthy, Michael D; Maly, Monica R

2018-01-01

Certain exercises could overload the osteoarthritic knee. We developed an exercise program from yoga postures with a minimal knee adduction moment for knee osteoarthritis. The purpose was to compare the effectiveness of this biomechanically-based yoga exercise (YE), with traditional exercise (TE), and a no-exercise attention-equivalent control (NE) for improving pain, self-reported physical function and mobility performance in women with knee osteoarthritis. Single-blind, three-arm randomized controlled trial. Community in Southwestern Ontario, Canada. A convenience sample of 31 women with symptomatic knee osteoarthritis was recruited through rheumatology, orthopaedic and physiotherapy clinics, newspapers and word-of-mouth. Participants were stratified by disease severity and randomly allocated to one of three 12-week, supervised interventions. YE included biomechanically-based yoga exercises; TE included traditional leg strengthening on machines; and NE included meditation with no exercise. Participants were asked to attend three 1-hour group classes/sessions each week. Primary outcomes were pain, self-reported physical function and mobility performance. Secondary outcomes were knee strength, depression, and health-related quality of life. All were assessed by a blinded assessor at baseline and immediately following the intervention. The YE group demonstrated greater improvements in KOOS pain (mean difference of 22.9 [95% CI, 6.9 to 38.8; p = 0.003]), intermittent pain (mean difference of -19.6 [95% CI, -34.8 to -4.4; p = 0.009]) and self-reported physical function (mean difference of 17.2 [95% CI, 5.2 to 29.2; p = 0.003]) compared to NE. Improvements in these outcomes were similar between YE and TE. However, TE demonstrated a greater improvement in knee flexor strength compared to YE (mean difference of 0.1 [95% CI, 0.1 to 0.2]. Improvements from baseline to follow-up were present in quality of life score for YE and knee flexor strength for TE, while both also

Vērtības izglītības sistēmas tiesību aktos un izglītības procesa dalībnieku izpratnē

OpenAIRE

Bokta, Rūta

2016-01-01

Latvijas valsts vērtības ir deklarētas LR Satversmē. Izglītībā svarīgākās vērtības ir minētas Izglītības likumā. Izglītības saturā tās aktualizē izglītības standarti. Pētījuma mērķis bija izpētīt, cik lielā mērā Satversmes un Izglītības likuma vērtības ir iekļautas izglītības standartos, kā tās izprot skolēni un kā skolotāji tās piedāvā skolēniem mācību procesā. Tika veikta literatūras un dokumentu analīze, kā arī veikts pētījums, lai noskaidrotu skolotāju un skolēnu personiskās vērtības, mā...

Laser-induced damage study of polymer PMMA; Motale-e-ye padid-e-ye khesarat-e mavvad-e polimeri PMMA dar moghabel-e barik-e-ye laizer

Energy Technology Data Exchange (ETDEWEB)

Mansour, N

2001-07-01

This article presents the results of bulk laser-induced damage measurements in polymer PMMA at 532 nm and 1064 nm for nanosecond laser pulses. The damage thresholds were measured for focused spot sizes ranging over two orders of magnitude. In this work, self-focusing effects were verified to be absent by measurements of breakdown thresholds using both linearly and circularly polarized light. At both 1064 nm and 532 nm, the dependence of the breakdown field, E{sub B}, on the spot size, {omega}, was empirically determined to be E{sub B} = C/{radical}{omega}, where C depends on the wavelength. The extracted value for C({lambda}) at 1064 nm is larger by a factor of 5 than at 532 nm. Possible reasons for this strong dispersion and mechanism for laser-induced damage in polymer materials will be discussed.

Direct and indirect fluorescent detection of tetracyclines using dually emitting carbon dots

International Nuclear Information System (INIS)

Qu, Fei; Sun, Zhe; Liu, Dongya; Zhao, Xianen; You, Jinmao

2016-01-01

The authors describe dual-emission carbon nanodots containing blue emitters (BE; peak emission at 385 nm under 315 nm excitation) and yellow emitters (YE; peak emission at 530 nm under 365 nm excitation), and how they can be applied to direct and indirect determination of tetracyclines (TCs). The direct detection scheme is based on the finding that tetracycline (TET), oxytetracycline, chlortetracycline and doxycycline quench the two emissions of the carbon dots. While direct determination is rapid and convenient, it cannot differentiate between TCs. The indirect detection scheme, in contrast, is based on the finding that Al (III) ions enhance the fluorescence of the YE in the carbon dots, and that they cause a blue shift in emission. It is, however, known that TET forms a strong complex with Al (III), and this can inhibit the interaction between Al (III) and the YE, so that the fluorescence of YE is not enhanced and blue-shifted by Al (III) in the presence of TET. This finding is exploited in a fluorescence turn-on/off assay for TET that can distinguish TET from other TCs. The linear range of indirect determination for TET extends from 1 nM to 30 μM, and the limit of detection is 0.52 nM. The indirect method was successfully applied to the determination of TET in spiked milk, fish and pork, and recoveries ranged from 91.7 to 102 %. (author)

MONSOONS MUDE AND GOLD MUSONLAR GEMİ VE ALTIN

Directory of Open Access Journals (Sweden)

Paul LUNDE

2009-12-01

Full Text Available The “global economy” of the Middle Ages was created by linking the Indian Ocean trading networks with those of the Mediterranean Sea and its African and European hinterlands. These products, together with ceramics, textiles and sugar provided from Egypt and Syria, reached European markets almost exclusively through the Italian maritime republics of Amalfi, Pisa, Genoa and Venice. Especially the direction of the monsoon winds in the Indian Ocean and the course of the Venice trade ships were at the same direction. Thereby, Venice trade ships set out toward the end of August and made their way slowly through the Adriatic and the Aegean to Cyprus and Alexandria, timing their arrival there to coincide with the availability of monsoon-borne and by this way the products which are ned carried through Europe. İt is important to emphasize this subject that North Europe economy depends on this Monsoons where they became at Indian Ocean. As a maritime republic dedicated itself to the international trade, Venice was an anomaly in a feudal Europe that measured wealth by land, not money. Therefor this idea were encouraging their believing about ending the monopoly of the Muslim trade at the Indian Ocean. Ortaçağın global ekonomisini Hint Okyanusu ticaret hattı ile Akdeniz, Afrika ve Avrupa Hinterlantları arasındaki ticaret bağlantısı teşkil ediyordu. Avrupa ekonomisindeki gelişmelere paralel olarak Batı dünyasının gereksinim duyduğu ve Mısır ile Suriye’den tedarik edilen şeker, tekstil, seramik gibi ürünler Amalfi, Pisa, Ceneviz ve Venedik gibi İtalyan Cumhuriyetleri aracılığıyla Avrupa pazarlarına taşınmaktaydı. Özellikle Hint Okyanusu üzerindeki muson rüzgârlarının yönleriyle Venedik ticaret gemilerinin rotaları aynı doğrultudaydı. Bu suretle Ağustos ayının sonuna doğru İtalya’dan ayrılan gemiler, Adriyatik, Ege ve Kıbrıs rotasından İskenderiye’ye ulaştığı esnada musonlarla kar

PVC esaslı CTP kesme atığı dolgulu malzemelerin termal özelliklerinin incelenmesi

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Arzu Özüyağlı

2016-08-01

Full Text Available Bu çalışmada, PVC üretiminde kullanılan CaCO3 dolgu malzemesi yerine, sanayi atığı kullanılması sonucu termal özelliklerdeki değişim araştırılmıştır. Kullanılan sanayi atığı CTP boru üretiminden sulu kesim sırasında çıkmakta ve SiO2, cam elyaf ve polyester reçine içermektedir. Sulu çamur halinde filtre presten çıkan atık fabrikadan alındıktan sonra kurutma ve eleme işlemleri uygulanarak toz formuna getirilmiştir. Numuneler PVC, CTP atık tozu ve prosese yardımcı maddeler mikserde karıştırılarak ekstrüzyon yöntemi ile profil şeklinde üretilmiştir. Atık toz PVC’ye oranla ağırlıkça %5-%70 oranlarında dolgu malzemesi olarak kullanılmıştır. Kalsit (CaCO3 katkılı ve katkısız PVC numuneleri de benzer proses parametreleri kullanılarak üretilmiştir. Üretilen numuneler, seramik krozeler kullanılarak DTA-TG analizleri yapılmıştır.

İMDAT AVŞAR AND HIS STORYTELLING İMDAT AVŞAR VE HİKÂYECİLİĞİ

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Zehra YAZBAHAR

2011-01-01

Full Text Available With his stories in his first book which is Steppe Which Fade To Crocuses he published in 2010, Imdat Avşar reflects our society and our traditional values. In this study which is primarily composed of two major parts, after giving brief information about Imdat Avşar in the first section, the art of storytelling will be part in the second section and the stories in the mentioned book are gotten the grips with narrator, viewpoint, content, characters, language and style. İmdat Avşar, 2010 yılında yayımladığı Çiğdemleri Solan Bozkır isimli ilk hikâye kitabındaki hikâyeleri ile aynasını Türk toplumuna ve onun geleneksel değerlerine tutar. Esas itibariyle iki ana bölümden oluşan bu çalışmada, ilk bölümde İmdat Avşar hakkında kısa bir bilgi verildikten sonra ikinci bölümde hikâyeciliğine geçilecek ve sözü edilen kitabındaki hikâyeleri, anlatıcı ve bakış açısı, içerik ve kişiler kadrosu, dil ve üslûp başlıkları altında ele alınacaktır.

Prospective Study of Alcohol Drinking, Smoking, and Pancreatitis: The Multiethnic Cohort.

Science.gov (United States)

Setiawan, Veronica Wendy; Pandol, Stephen J; Porcel, Jacqueline; Wilkens, Lynne R; Le Marchand, Loïc; Pike, Malcolm C; Monroe, Kristine R

2016-07-01

We conducted a prospective analysis of 145,886 participants in the multiethnic cohort to examine the relationship of alcohol drinking and smoking with pancreatitis. Pancreatitis cases were categorized as gallstone-related acute pancreatitis (GSAP) (N = 1,065), non-GSAP (N = 1,222), and recurrent acute (RAP)/chronic pancreatitis (CP) (N = 523). We used the baseline questionnaire to identify alcohol intake and smoking history. Associations were estimated by hazard ratios (HRs) and 95% confidence intervals (CIs) using Cox models. Cigarette smoking was associated with non-GSAP and RAP/CP. Moderate alcohol intake was inversely associated with all types of pancreatitis in women (HRs, 0.66 to 0.81 for risk of non-GS pancreatitis associated with current smoking was highest among men who consumed more than 4 drinks per day (HR, 2.06; 95% CI, 1.28-3.30), whereas among never smokers, moderate drinking was associated with a reduced risk (HR, 0.70; 95% CI, 0.51-0.96). In women, drinking less than 2 drinks per day was associated with a reduced risk of GSAP among never smokers (HR, 0.61; 95% CI, 0.46-0.80). Smoking is a risk factor for non-GS pancreatitis. Moderate alcohol intake is protective against all types of pancreatitis in women and against RAP/CP in men.

'Poker' association of weekly alternating 5-fluorouracil, irinotecan, bevacizumab and oxaliplatin (FIr-B/FOx) in first line treatment of metastatic colorectal cancer: a phase II study

International Nuclear Information System (INIS)

Bruera, Gemma; Ficorella, Corrado; Ricevuto, Enrico; Santomaggio, Alessandra; Cannita, Katia; Baldi, Paola Lanfiuti; Tudini, Marianna; De Galitiis, Federica; Mancini, Maria; Marchetti, Paolo; Antonucci, Adelmo

2010-01-01

This phase II study investigated efficacy and safety of weekly alternating Bevacizumab (BEV)/Irinotecan (CPT-11) or Oxaliplatin (OHP) associated to weekly 5-Fluorouracil (5-FU) in first line treatment of metastatic colorectal carcinoma (MCRC). Simon two-step design: delta 20% (p 0 50%, p 1 70%), power 80%, α 5%, β 20%. Projected objective responses (ORR): I step, 8/15 patients (pts); II step 26/43 pts. Schedule: weekly 12 h-timed-flat-infusion/5-FU 900 mg/m 2 , days 1-2, 8-9, 15-16, 22-23; CPT-11 160 mg/m 2 plus BEV 5 mg/kg, days 1,15; OHP at three dose-levels, 60-70-80 mg/m 2 , days 8, 22; every 4 weeks. Fifty consecutive, unselected pts < 75 years were enrolled: median age 63; young-elderly (yE) 24 (48%); liver metastases (LM) 33 pts, 66% Achieved OHP recommended dose, 80 mg/m 2 . ORR 82% intent-to-treat and 84% as-treated analysis. Median progression-free survival 12 months. Equivalent efficacy was obtained in yE pts. Liver metastasectomies were performed in 26% of all pts and in 39% of pts with LM. After a median follow-up of 21 months, median overall survival was 28 months. Cumulative G3-4 toxicities per patient: diarrhea 28%, mucositis 6%, neutropenia 10%, hypertension 2%. They were equivalent in yE pts. Limiting toxicity syndromes (LTS), consisting of the dose-limiting toxicity, associated or not to G2 or limiting toxicities: 44% overall, 46% in yE. Multiple versus single site LTS, respectively: overall, 24% versus 20%; yE pts, 37.5% versus 8%. Poker combination shows high activity and efficacy in first line treatment of MCRC. It increases liver metastasectomies rate and can be safely administered. Osservatorio Nazionale sulla Sperimentazione Clinica dei Medicinali (OsSC) Agenzia Italiana del Farmaco (AIFA) Numero EudraCT 2007-004946-34

Identification and classification of genes regulated by phosphatidylinositol 3-kinase- and TRKB-mediated signalling pathways during neuronal differentiation in two subtypes of the human neuroblastoma cell line SH-SY5Y

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Sakaki Yoshiyuki

2008-10-01

Full Text Available Abstract Background SH-SY5Y cells exhibit a neuronal phenotype when treated with all-trans retinoic acid (RA, but the molecular mechanism of activation in the signalling pathway mediated by phosphatidylinositol 3-kinase (PI3K is unclear. To investigate this mechanism, we compared the gene expression profiles in SK-N-SH cells and two subtypes of SH-SY5Y cells (SH-SY5Y-A and SH-SY5Y-E, each of which show a different phenotype during RA-mediated differentiation. Findings SH-SY5Y-A cells differentiated in the presence of RA, whereas RA-treated SH-SY5Y-E cells required additional treatment with brain-derived neurotrophic factor (BDNF for full differentiation. After exposing cells to a PI3K inhibitor, LY294002, we identified 386 genes and categorised these genes into two clusters dependent on the PI3K signalling pathway during RA-mediated differentiation in SH-SY5Y-A cells. Transcriptional regulation of the gene cluster, including 158 neural genes, was greatly reduced in SK-N-SH cells and partially impaired in SH-SY5Y-E cells, which is consistent with a defect in the neuronal phenotype of these cells. Additional stimulation with BDNF induced a set of neural genes that were down-regulated in RA-treated SH-SY5Y-E cells but were abundant in differentiated SH-SY5Y-A cells. Conclusion We identified gene clusters controlled by PI3K- and TRKB-mediated signalling pathways during the differentiation of two subtypes of SH-SY5Y cells. The TRKB-mediated bypass pathway compensates for impaired neural function generated by defects in several signalling pathways, including PI3K in SH-SY5Y-E cells. Our expression profiling data will be useful for further elucidation of the signal transduction-transcriptional network involving PI3K or TRKB.

Eerder anders as elders: Gerrie Snyman se bydrae in die konteks van die Gereformeerde teologie

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Hans J.M. van Deventer

2010-03-01

Full Text Available Rather different than elsewhere: Gerrie Snyman�s contribution in the context of Reformed theology Prof Gerrie Snyman�s book Om die Bybel anders te lees: �n etiek van Bybellees (2007 attracted considerable attention in Afrikaans-speaking reformed circles in South Africa. In this article, some of the responses to and reviews of the book are studied in order to assess the publication�s impact. Moreover, the article aims to determine whether the book will contribute to future reflections and discussions on the use of the Bible in this context. It is concluded that the preferred method of interpretation in the Reformed Church in South Africa calls for a thorough revision. The so-called �grammatical-historical method� of interpretation can no longer be regarded as the most appropriate and sole �Reformed method� of interpretation.�--- Abstract translated into Sipedi ---Go fapana le t�e dingwe: seabe sa Gerrie Snyman go teologie ya RefomoPuku ya Profesa Gerrie Snyman, Om die Bybel anders te lees: �n Etiek van Bybellees (2007, e gogile �edi ye kgolo ya maloko a kereke ya Refomo mo Afrika-Borwa(RCSA/GKSA. Mo pampiring ye re ithuta t�e dingwe t�a dikarabo le ditshekatsheko t�a puku ye go ela khuet�o ya yona. Go feta fao, pampiri ye e nepile go bona ge e ba puku ye e tlo ba le seabe go dikakanyo le dipoledi�ano mabapi le t�homi�o ya Beibele ditabeng t�a mohuta wo. Re ruma ka go re, mokgwa wa tshekatsheko ya Bibele wa Kereke ya Refomo mo Afrika-Borwa o hloka go lekodi�i�wa le go boelet�wa. Mokgwa wa go hlatholla Bibele ka go sekaseka popopolelo(gramatika le histori ya tlholego ya yona, o ka se sa t�ewa e le wona wa maleba o nno�i wa tshekatsheko goba go ba wona �Mokgwa wa Refomo� wa go fetleka Bibele.--- End of translation ---

China Report: Political, Sociological and Military Affairs.

Science.gov (United States)

1983-03-18

Production Brigade of Guangbao Commune in raising chickens and rabbits in a big way. We must mobilize the commune member house- holds to utilize...The state and the commune, production brigades, and production teams operate fish farms, some of which raise fry . Why not go ahead with raising fish...Wei Xinyi, Huang Yu, Yang Jike, Guo Tixiang, Meng Fulin, Hu Tan, Zhu Nong, Fang Shiliang, Wang Zenong, Pan Ezhang, Liu Zhengwen, Chen Tianren, Ma

Buruli Ulcer in Cameroon: The Development and Impact of the National Control Programme.

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Earnest Njih Tabah

2016-01-01

Full Text Available Cameroon is endemic for Buruli ulcer (BU and organised institutional BU control began in 2002. The objective was to describe the evolution, achievements and challenges of the national BU control programme (NBUCP and to make suggestions for scaling up the programme.We analysed collated data on BU from 2001 to 2014 and reviewed activity reports NBUCP in Cameroon. Case-detection rates and key BU control indicators were calculated and plotted on a time scale to determine trends in performance. A linear regression analysis of BU detection rate from 2005-2014 was done. The regression coefficient was tested statistically for the significance in variation of BU detection rate.In 14 years of BU control, 3700 cases were notified. The BU detection rate dropped significantly from 3.89 to 1.45 per 100 000 inhabitants. The number of BU endemic health districts rose from two to 64. Five BU diagnostic and treatment centres are functional and two more are planned for 2015. The health system has been strengthened and BU research and education has gained more interest in Cameroon.Although institutional BU control Cameroon only began 30 years after the first cases were reported in 1969, a number of milestones have been attained. These would serve as stepping stones for charting the way forward and improving upon control activities in the country if the major challenge of resource allocation is dealt with.

Combustion and emissions characteristics of high n-butanol/diesel ratio blend in a heavy-duty diesel engine and EGR impact

International Nuclear Information System (INIS)

Chen, Zheng; Wu, Zhenkuo; Liu, Jingping; Lee, Chiafon

2014-01-01

Highlights: • Effects of EGR on high n-butanol/diesel ratio blend (Bu40) were investigated and compared with neat diesel (Bu00). • Bu40 has higher NOx due to wider combustion high-temperature region. • Bu40 has lower soot due to local lower equivalence ratio distribution. • Bu40 has higher CO due to lower gas temperature in the late expansion process. • For Bu40, EGR reduces NOx emissions dramatically with no obvious influence on soot. - Abstract: In this work, the combustion and emission fundamentals of high n-butanol/diesel ratio blend with 40% butanol (i.e., Bu40) in a heavy-duty diesel engine were investigated by experiment and simulation at constant engine speed of 1400 rpm and an IMEP of 1.0 MPa. Additionally, the impact of EGR was evaluated experimentally and compared with neat diesel fuel (i.e., Bu00). The results show that Bu40 has higher cylinder pressure, longer ignition delay, and faster burning rate than Bu00. Compared with Bu00, moreover, Bu40 has higher NOx due to wider combustion high-temperature region, lower soot due to local lower equivalence ratio distribution, and higher CO due to lower gas temperature in the late expansion process. For Bu40, EGR reduces NOx emissions dramatically with no obvious influence on soot. Meanwhile, there is no significant change in HC and CO emissions and indicated thermal efficiency (ITE) with EGR until EGR threshold is reached. When EGR rate exceeds the threshold level, HC and CO emissions increase dramatically, and ITE decreases markedly. Compared with Bu00, the threshold of Bu40 appears at lower EGR rate. Consequently, combining high butanol/diesel ratio blend with medium EGR has the potential to achieve ultra-low NOx and soot emissions simultaneously while maintaining high thermal efficiency level

Teng-Long-Bu-Zhong-Tang, a Chinese herbal formula, enhances anticancer effects of 5--Fluorouracil in CT26 colon carcinoma.

Science.gov (United States)

Deng, Shan; Hu, Bing; An, Hong-Mei; Du, Qin; Xu, Ling; Shen, Ke-Ping; Shi, Xiu-Feng; Wei, Meng-Meng; Wu, Yang

2013-06-08

Colorectal cancer remains one of the leading causes of cancer death worldwide. Traditional Chinese Medicine (TCM) has played a positive role in colorectal cancer treatment. There is a great need to establish effective herbal formula for colorectal cancer treatment. Based on TCM principles and clinical practices, we have established an eight herbs composed formula for colorectal cancer treatment, which is Teng-Long-Bu-Zhong-Tang (TLBZT). We have demonstrated the anticancer effects of TLBZT against colorectal carcinoma in vitro. In present study, we evaluated the anticancer potential of TLBZT, used alone or in combination with low dose of 5-Fluorouracil (5-Fu), in CT26 colon carcinoma in vivo. CT26 colon carcinoma was established in BALB/c mice and treated with TLBZT, 5-Fu, or TLBZT plus 5-Fu. The tumor volumes were observed. Apoptosis was detected by TUNEL assay. Caspases activities were detected by colorimetric assay. Cell senescence was indentified by senescence β-galactosidase staining. Gene expression and angiogenesis was observed by immunohistochemistry or western blot. TLBZT significantly inhibited CT26 colon carcinoma growth. TLBZT elicited apoptosis in CT26 colon carcinoma, accompanied by Caspase-3, 8, and 9 activation and PARP cleavage, and downregulation of XIAP and Survivin. TLBZT also induced cell senescence in CT26 colon carcinoma, with concomitant upregulation of p16 and p21 and downregulation of RB phosphorylation. In addition, angiogenesis and VEGF expression in CT26 colon carcinoma was significantly inhibited by TLBZT treatment. Furthermore, TLBZT significantly enhanced anticancer effects of 5-Fu in CT26 colon carcinoma. TLBZT exhibited significantly anticancer effect, and enhanced the effects of 5-Fu in CT26 colon carcinoma, which may correlate with induction of apoptosis and cell senescence, and angiogenesis inhibition. The present study provides new insight into TCM approaches for colon cancer treatment that are worth of further study.

Identification of Multiple Ingredients for a Traditional Chinese Medicine Preparation (Bu-yang-huan-wu-tang by Liquid Chromatography Coupled with Tandem Mass Spectrometry

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Tung-Hu Tsai

2013-09-01

Full Text Available Bu-yang-huan-wu-tang (BYHWT is a popular Traditional Chinese Medicine formula consisting of seven herbal medicines (Astragalus membranaceus, Angelica sinensis, Paeonia lactiflora, Ligusticum chuanxiong, Carthamus tinctorius, Amygdalus persica and Pheretima aspergillum, that has been used in China for centuries to overcome stroke-induced disability. To ensure the consistency of quality, a reliable analytical method is required, therefore, we developed a liquid chromatography with tandem mass spectrometry (LC-MS/MS method for quantitative analysis of the major constituents in BYHWT. The herbal ingredients consisting of the cycloartane-type triterpene glycosides of astragaloside I, astragaloside II and astragaloside IV; isoflavones of formononetin, ononin calycosin, calycosin-7-O-β-d-glucoside; ligustilide and paeoniflorin were separated on a C18 column with gradient elution of methanol/10 mM ammonium acetate buffer–formic acid (100:0.1, v/v. This study was performed by a mass spectrometer using electrospray ionization (ESI with positive ionization ions monitored in the multiple reaction-monitoring (MRM mode. The linearity, accuracy, precision, limit of detection (LOD and lower limit of quantification (LLOQ were validated for this quantification method, and the sensitivity, reliability and reproducibility were all confirmed. The experiments provided a good method for analyzing BYHWT extracts. This study also quantitated the active components in various brands of commercially available products. The results indicated that the pharmaceutical industrial products of BYHWT exhibited considerable variation in their contents of the herbal compounds.

MUON DETECTORS: CSC

CERN Document Server

R. Breedon

2010-01-01

Toward the end of last year, a few water leaks, one of them severe, were discovered in the endcap cooling system on the YE1 disks that not only services the cathode strip chambers, but also the endcap resistive plate chambers, electromagnetic calorimeter, and disks. The problem was traced to a bushing adaptor present on each return line that in some cases had been over-tightened. There were close to 400 such bushings on all the endcap disks that could potentially cause a leak. Most of these are inaccessible to fix or valve off when CMS is closed, so a future leak could require shutting down an entire disk. It was therefore decided to open CMS during the December shutdown and replace all the bushing assemblies on the YE1 disks with swivel fittings that do  not have this potential problem. From 8 to 22 January, 6 technicians from the Polish ZEC company and 2 engineers from the Physical Sciences Laboratory in Wisconsin not only made the replacements on YE1, but on all the other endcap disks as well. ...

Open fermentative production of L-lactic acid with high optical purity by thermophilic Bacillus coagulans using excess sludge as nutrient.

Science.gov (United States)

Ma, Kedong; Maeda, Toshinari; You, Huiyan; Shirai, Yoshihito

2014-01-01

The development of a low-cost polymer-grade L-lactic acid production process was achieved in this study. Excess sludge hydrolyzate (ESH) was chosen as nutrient source for the objective of reducing nutrient cost in lactic acid production. 1% of ESH had high performance in lactic acid production relative to 2g/l yeast extract (YE) while the production cost of ESH was much lower than that of YE, indicating ESH was a promising substitute of YE. By employing a thermophilic strain of Bacillus coagulans (NBRC 12583), non-sterilized batch and repeated batch L-lactic acid fermentation was successfully performed, and the optical purity of L-lactic acid accumulated was more than 99%. Moreover, the factors associated with cell growth and lactic acid fermentation was investigated through a two-stage lactic acid production strategy. Oxygen played an important role in cell growth, and the optimal condition for cell growth and fermentation was pH 7.0 and 50°C. Copyright © 2013 Elsevier Ltd. All rights reserved.

An Experimental Validated Control Strategy of Maglev Vehicle-Bridge Self-Excited Vibration

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Lianchun Wang

2017-01-01

Full Text Available This study discusses an experimentally validated control strategy of maglev vehicle-bridge vibration, which degrades the stability of the suspension control, deteriorates the ride comfort, and limits the cost of the magnetic levitation system. First, a comparison between the current-loop and magnetic flux feedback is carried out and a minimum model including flexible bridge and electromagnetic levitation system is proposed. Then, advantages and disadvantages of the traditional feedback architecture with the displacement feedback of electromagnet yE and bridge yB in pairs are explored. The results indicate that removing the feedback of the bridge’s displacement yB from the pairs (yE − yB measured by the eddy-current sensor is beneficial for the passivity of the levitation system and the control of the self-excited vibration. In this situation, the signal acquisition of the electromagnet’s displacement yE is discussed for the engineering application. Finally, to validate the effectiveness of the aforementioned control strategy, numerical validations are carried out and the experimental data are provided and analyzed.

Dependent of electrical resistivity of thin wire on magnetic field and temperature; Vabastegi-ye moghavemat-e elekteriki-ye simha-ye barik be meidan-e meghnatisi va dama

Energy Technology Data Exchange (ETDEWEB)

Sadeghi, E [Yasouj University, Physics Department, Yasouj(Iran, Islamic Republic of); Zare, M [Shiraz Payam Noor University, shiraz(Iran, Islamic Republic of)

2006-04-01

Variation of electrical resistivity of Bismuth nano wire versus magnetic field the and temperature are considered. We study the size effect and surface scattering of the carrier in thin wire for systems with ellipsoidal Fermi surfaces. Results are in good agreement with experimental points.

Safety Analysis Report - Packages, 9965, 9968, 9972-9975 Packages

International Nuclear Information System (INIS)

Van Alstine, M.N.

1999-01-01

This Safety Analysis Report for Packaging (SARP) documents the performance of the 9965 B, 9968 B, 9972 B(U), 9973 B(U), 9974 B(U), and 9975 B(U) packages in satisfying the regulatory safety requirements of the Code of Federal Regulations (CFR) 711 and the International Atomic Energy Agency (IAEA) Safety Series No. 6, Regulations for the Safe Transport of Radioactive Material, 1985 edition2. Results of the analysis and testing performed on the 9965 B, 9968 B, 9972 B(U), 9973 B(U), 9974 B(U), and 9975 B(U) packages are presented in this SARP, which was prepared in accordance with U.S. Department of energy (DOE) Order 5480.33 and in the format specified in the Nuclear Regulatory Commission (NRC) Regulatory Guides 7.94 and 7.10.5

ONE MEANING OF A WORD IN THE BOOK OF DEDE KORKUT: KAZAVAT/KARAVAT DEDE KORKUT’TA BİR KELİME BİR ANLAM: KAZAVAT/KARAVAT

Directory of Open Access Journals (Sweden)

Muammer Mete TAŞLIOVA

2011-09-01

Full Text Available Dede Korkut Stories are among the important sources of Turkish culture. Poetry and story come together. Many publications have been made about the book in Turkey and abroad. Samples were prepared versions of novels and tales. There are also examples of opera and theater. New experiments are made in the form of television series. Considered the source of the classic Turkish folk storytelling. Turkish culture and literature is the source of the important issues. But musicality aspect is not dealt with yet sufficiently because the music needs to be considered poems. Word structure varies as. Different dialect, a combination of features. But this harmony is a factor that. The oldest written text to be read some words in different ways. This article focuses on a word. There are different readings of the word “kazavat, karavat”. About the different meanings of the word have been suggested. This article will focus on the meanings. In addition, the proposal will be a new meaning. Dede Korkut Hikâyeleri Türk kültürünün önemli kaynakları arasındadır. Şiir ve hikâye bir aradadır. Türkiye'de ve yurt dışında kitap hakkında birçok yayın yapılmıştır. Roman ve masal versiyonları hazırlanmıştır. Opera ve tiyatro örnekleri de bulunmaktadır. Televizyon dizisi biçiminde yeni denemeler de yapılmaktadır. Klasik Türk halk hikâyeciliğinin de kaynağı sayılır. Türk kültürüne ve edebiyatına ait önemli konulara kaynaklık etmektedir. Fakat müzikalite yönüyle henüz yeterince ele alınmamıştır oysa şiiri müzikle düşünmek gerekmektedir. Kelime yapısı olarak da çeşitlilik gösterir. Farklı lehçe özellikleri bir aradadır. Fakat bu ahengi sağlayan bir unsurdur. Arap alfabesi ile yazılmış metin olduğu için bazı kelimeler farklı biçimlerde okunmuştur. Bu makalede bir kelime üzerinde durulmaktadır. Kelimenin “kazavat, karavat” farklı okunuşları bulunmaktadır. Kelime hakkında farklı anlamlar

NOTES ON DIFFERENCE IN ORKHON MONUMENTS READING AND INTERPRETING MADE BY TURCOLOGIST OF TURKISH ORIGIN TÜRK ASILLI TÜRKOLOGLARIN ORHUN YAZITLARINI OKUMA VE YORUMLAMALARINDAKİ FARKLILIKLAR ÜZERİNE NOTLAR

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Mehmet Cihat ÜSTÜN

2010-04-01

Full Text Available This study is related to the Orkhon inscriptions which are the first examples of Turkish language and have an important place in Asian culture. After a period about 1200 years the turcologist worked on, the Orkhon inscriptions were tried to be read and interpreted taking into acount of Göktürk culture, history and lifestyle. Every new component discovered concerning the lifestyle of Göktürk would make the Orkhon inscriptions possible to be read and interpreted in a different way. Approximately 120 yearly assessment process is not finally over. Orkhon inscriptions have preserved its magical and peculiar structure which are open to new proposals and recommendations. 120-year period evaluated in this study are subject to the Orkhon inscriptions on the Turkish citizen who serves turcology reading and interpretation of research proposals are evaluated in comparison. Bu çalışma, Orta Asya Türk kültürü içerisinde mühim bir yer işgal eden ve Türk yazı dilinin ilk vesikaları olan Orhun yazıtları ile ilgilidir. Yaklaşık 1200 yıllık bir süreçten sonra Türkologların üzerinde çalışmalar yaptıkları Orhun yazıtları Göktürk kültürü, tarihi ve yaşam tarzı dikkate alınarak okunmaya ve yorumlanmaya çalışılmıştır. Göktürklerin yaşantısına dair keşfedilen her türlü yeni öğe bu yazıtların farklı okunmasına ve yorumlanmasına imkân tanıyacaktır. Yaklaşık 120 yıllık değerlendirme süreci nihayete ermiş değildir. Orhun yazıtları yeni teklif ve önerilere açık kendine özgü sihirli yapısını günümüzde de muhafaza etmektedir. Bu çalışmada, 120 yıllık süreç içerisinde değerlendirmeye tabi tutulan Orhun yazıtları üzerinde Türk asıllı olup Türkoloji’ye hizmet eden araştırmacıların okuma ve yorumlama teklifleri karşılaştırmalı olarak verilmeye çalışılmıştır.

Evaluation of effects of busulfan and DMA on SOS in pediatric stem cell recipients.

Science.gov (United States)

Kerl, Kornelius; Diestelhorst, Christian; Bartelink, Imke; Boelens, Jaap; Trame, Mirjam N; Boos, Joachim; Hempel, Georg

2014-02-01

Busulfan (Bu) is a DNA-alkylating agent used for myeloablative conditioning in stem cell transplantation in children and adults. While the use of intravenous rather than oral administration of Bu has reduced inter-individual variability in plasma levels, toxicity still occurs frequently after hematopoietic stem cell transplantation (HSCT). Toxicity (especially hepatotoxic effects) of intravenous (IV) Bu may be related to both Bu and/or N,N-dimethylacetamide (DMA), the solvent of Bu. In this study, we assessed the relation between the exposure of Bu and DMA with regards to the clinical outcome in children from two cohorts. In a two-centre study Bu and DMA AUC (area under the curve) were correlated in pediatric stem cell recipients to the risk of developing SOS and to the clinical outcome. In patients receiving Bu four times per day Bu levels >1,500 µmol/L minute correlate to an increased risk of developing a SOS. In the collective cohort, summarizing data of all 53 patients of this study, neither high area under the curve (AUC) of Bu nor high AUC of DMA appears to be an independent risk factor for the development of SOS in children. In this study neither Bu nor DMA was observed as an independent risk factor for the development of SOS. To identify subgroups (e.g., infants), in which Bu or DMA might be risk factors for the induction of SOS, larger cohorts have to be evaluated. © 2013 Wiley Periodicals, Inc.

AcEST: DK944801 [AcEST

Lifescience Database Archive (English)

Full Text Available 1. 5' end sequence. DK944801 - Show DK944801 Clone id YMU02A01NGRL0007_D21 Library YMU02 Length 485 Definiti...on Adiantum capillus-veneris mRNA. clone: YMU02A01NGRL0007_D21. 5' end sequence. Accession DK944801 Tissue t... 25:3389-3402. Query= DK944801|Adiantum capillus-veneris mRNA, clone: YMU02A01NGRL0007_D21, 5' (472 letters)...lfolobus solfata... 32 1.8 sp|O13801|YE04_SCHPO Uncharacterized RNA-binding prote...DDPKDTSDYTIDHGLEELEELRKQVFGNDKIVLLGHSYGGALAIAYALKY 129 >sp|O13801|YE04_SCHPO Uncharacterized RNA-binding pro

A generalization of Sachdev-Ye-Kitaev

Energy Technology Data Exchange (ETDEWEB)

Gross, David J.; Rosenhaus, Vladimir [Kavli Institute for Theoretical Physics, University of California,Santa Barbara, CA 93106 (United States)

2017-02-17

The SYK model: fermions with a q-body, Gaussian-random, all-to-all interaction, is the first of a fascinating new class of solvable large N models. We generalize SYK to include f flavors of fermions, each occupying N{sub a} sites and appearing with a q{sub a} order in the interaction. Like SYK, this entire class of models generically has an infrared fixed point. We compute the infrared dimensions of the fermions, and the spectrum of singlet bilinear operators. We show that there is always a dimension-two operator in the spectrum, which implies that, like in SYK, there is breaking of conformal invariance and maximal chaos in the infrared four-point function of the generalized model. After a disorder average, the generalized model has a global O(N{sub 1})×O(N{sub 2})×…×O(N{sub f}) symmetry: a subgroup of the O(N) symmetry of SYK; thereby giving a richer spectrum. We also elucidate aspects of the large q limit and the OPE, and solve q=2 SYK at finite N.

Design and synthesis of single-source molecular precursors to homogeneous multi-component oxide materials

Science.gov (United States)

Fujdala, Kyle Lee

This dissertation describes the syntheses of single-source molecular precursors to multi-component oxide materials. These molecules possess a core metal or element with various combinations of -OSi(O tBu)3, -O2P(OtBu) 2, and -OB[OSi(OtBu)3] 2 ligands. Such molecules decompose under mild thermolytic conditions (models for oxide-supported metal species and multi-component oxides. Significantly, the first complexes to contain three or more heteroelements suitable for use in the TMP method have been synthesized. Compounds for use as single-source molecular precursors have been synthesized containing Al, B, Cr, Hf, Mo, V, W, and Zr, and their thermal transformations have been examined. Heterogeneous catalytic reactions have been examined for selected materials. Also, cothermolyses of molecular precursors and additional molecules (i.e., metal alkoxides) have been utilized to provide materials with several components for potential use as catalysts or catalyst supports. Reactions of one and two equivs of HOSi(OtBu) 3 with Cr(OtBu)4 afforded the first Cr(IV) alkoxysiloxy complexes (tBuO) 3CrOSi(OtBu)3 and ( tBuO)2Cr[OSi(OtBu) 3]2, respectively. The high-yielding, convenient synthesis of (tBuO)3CrOSi(O tBu)3 make this complex a useful single-source molecular precursor, via the TMP method, to Cr/Si/O materials. The thermal transformations of (tBuO)3CrOSi(O tBu)3 and (tBuO) 2Cr[OSi(OtBu)3]2 to chromia-silica materials occurr at low temperatures (≤180°C), to give isobutene as the major carbon-containing product. The material generated from the solid-state conversion of (tBuO) 3CrOSi(OtBu)3 (CrOS ss) has an unexpectedly high surface area of 315 m2 g-1 that is slightly reduced to 275 m2 g-1 after calcination at 500°C in O2. The xerogel obtained by the thermolysis of an n-octane solution of (tBuO)3CrOSi(O tBu)3 (CrOSixg) has a surface area of 315 m2 g-1 that is reduced to 205 m2 g-1 upon calcination at 500°C. Powder X-ray diffraction (PXRD) analysis revealed that Cr2O 3 is

Radiation-produced electron migration along 5-bromouracil-substituted DNA in cells and in solutions

International Nuclear Information System (INIS)

Beach, C.M.

1981-01-01

Results of work by other investigators support the theory of charge migration in DNA. Charge transfer between nucleotides and electron and energy migration in solid state DNA have been detected, but no previous experiments have demonstrated charge migration in aqueous solutions of DNA or in DNA inside an E. coli cell. Such experiments were performed by substituting different amounts of 5-bromouracil (BU) for thymine in E. coli DNA and assaying for the amount of bromide given off from the reaction of bromouracil with hydrated electrons produced by ionizing radiation to form uracil-5-yl radicals and free bromide. By varying the amount of BU incorporated in the DNA, the average distance between the BU bases was varied, and because the number of BU/electron reactions was monitored by the amount of bromide released, the maximum average electron migration distance along the BU-DNA was estimated. Hydrated electrons, e/sub aq/, were shown to react with BU in BU-DNA with the resultant release of bromide with G(-BR - ) = 0.519 +- 0.062. OH radicals were half as reactive as e/sub aq/ toward producing bromide from BU-DNA. O 2 , which has been shown to transfer charge to BU in aqueous solution, did not transfer charge to BU-DNA. The CO 2 radical was shown to cause the release of bromide from BU-DNA at least as effectively as e/sub aq/. Charge migration was demonstrated, and the maximum average electron migration distance in aqueous solutions of BU-DNA was measured to be 8 to 10 base distances (assuming only intrastrand migration). Only 11% to 16% of the electrons produced attacked BU-DNA in aqueous solution, and only 1% resulted in bromide release from BU-DNA inside E. coli. Charge migration was demonstrated in BU-DNA inside E. coli., and the maximum average migration distance was measured to be 5 to 6 base distances

Two Blades-Up Runs Using the JetStream Navitus Atherectomy Device Achieve Optimal Tissue Debulking of Nonocclusive In-Stent Restenosis: Observations From a Porcine Stent/Balloon Injury Model.

Science.gov (United States)

Shammas, Nicolas W; Aasen, Nicole; Bailey, Lynn; Budrewicz, Jay; Farago, Trent; Jarvis, Gary

2015-08-01

To determine the number of runs with blades up (BU) using the JetStream Navitus to achieving optimal debulking in a porcine model of femoropopliteal artery in-stent restenosis (ISR). In this porcine model, 8 limbs were implanted with overlapping nitinol self-expanding stents. ISR was treated initially with 2 blades-down (BD) runs followed by 4 BU runs (BU1 to BU4). Quantitative vascular angiography (QVA) was performed at baseline, after 2 BD runs, and after each BU run. Plaque surface area and percent stenosis within the treated stented segment were measured. Intravascular ultrasound (IVUS) was used to measure minimum lumen area (MLA) and determine IVUS-derived plaque surface area. QVA showed that plaque surface area was significantly reduced between baseline (83.9%±14.8%) and 2 BD (67.7%±17.0%, p=0.005) and BU1 (55.4%±9.0%, p=0.005) runs, and between BU1 and BU2 runs (50.7%±9.7%, patherectomy. JetStream Navitus achieved optimal tissue debulking after 2 BD and 2 BU runs with no further statistical gain in debulking after the BU2 run. Operators treating ISR with JetStream Navitus may be advised to limit their debulking to 2 BD and 2 BU runs to achieve optimal debulking. © The Author(s) 2015.

Isolation and X-ray structures of four Rh(PCP) complexes including a Rh(I) dioxygen complex with a short O-O bond

KAUST Repository

Hayashi, Yukiko

2013-07-01

The reaction of RhCl3·H2O with tBu2P(CH2)5PtBu 2 afforded several complexes including [RhIII(H)Cl{ tBu2- P(CH2)2CH(CH2) 2PtBu2}] (1), [RhIIIHCl 2{tBu2P(CH2)5P tBu2}]2 (2), [RhICl{ tBu2P(CH2)2CH=CHCH2P tBu2}] (3) and [RhICl{tBu 2PCH2C(O)CH=CHCH2PtBu2}] (4). X-ray crystal structures of 3 and 4 showed that the C=C bond on the C 5 unit of tBu2P(CH2) 5PtBu2 is bound to Rh(I) in a η2 configuration. In 4, the Rh atom has a trigonal pyramidal coordination geometry. The X-ray crystal structure of 2 consists of two rhodium( III) centers bridged by two tBu2P(CH2)5P tBu2 ligands with two phosphorus atoms, one from each ligand, trans to one another. The crystal structure of the rhodium oxygen adduct with 1,3-bis(di-t-butylphosphinomethyl) benzene [RhO2{ tBu2PCH2(C6H3)CH 2PtBu2}] (5) was also investigated. In this species the O2 is η2 coordinated to the Rh(I) center with asymmetric Rh-O bond lengths (2.087(7) and 1.998(8) Å). The O-O bond distance is short (1.337(11) Å) with νO-O of 990.5 cm -1. DFT calculations on complex 5 yielded two η2- O2 structures that differed in energy by only 0.76 kcal/mol. The lower energy one (5a) had near C2 symmetry, and had nearly equal Rh-O bond lengths, while the higher energy structure (5b) had near Cs symmetry and generally good agreement with the experimental structure. The calculated UV-Vis and IR spectra of complex 5 are in excellent agreement with experiment. © 2012 Elsevier Ltd. All rights reserved.

Isolation and X-ray structures of four Rh(PCP) complexes including a Rh(I) dioxygen complex with a short O-O bond

KAUST Repository

Hayashi, Yukiko; Szalda, David J.; Grills, David C.; Hanson, Jonathan C.; Huang, Kuo-Wei; Muckerman, James T.; Fujita, Etsuko

2013-01-01

The reaction of RhCl3·H2O with tBu2P(CH2)5PtBu 2 afforded several complexes including [RhIII(H)Cl{ tBu2- P(CH2)2CH(CH2) 2PtBu2}] (1), [RhIIIHCl 2{tBu2P(CH2)5P tBu2}]2 (2), [RhICl{ tBu2P(CH2)2CH=CHCH2P tBu2}] (3) and [RhICl{tBu 2PCH2C(O)CH=CHCH2PtBu2}] (4). X-ray crystal structures of 3 and 4 showed that the C=C bond on the C 5 unit of tBu2P(CH2) 5PtBu2 is bound to Rh(I) in a η2 configuration. In 4, the Rh atom has a trigonal pyramidal coordination geometry. The X-ray crystal structure of 2 consists of two rhodium( III) centers bridged by two tBu2P(CH2)5P tBu2 ligands with two phosphorus atoms, one from each ligand, trans to one another. The crystal structure of the rhodium oxygen adduct with 1,3-bis(di-t-butylphosphinomethyl) benzene [RhO2{ tBu2PCH2(C6H3)CH 2PtBu2}] (5) was also investigated. In this species the O2 is η2 coordinated to the Rh(I) center with asymmetric Rh-O bond lengths (2.087(7) and 1.998(8) Å). The O-O bond distance is short (1.337(11) Å) with νO-O of 990.5 cm -1. DFT calculations on complex 5 yielded two η2- O2 structures that differed in energy by only 0.76 kcal/mol. The lower energy one (5a) had near C2 symmetry, and had nearly equal Rh-O bond lengths, while the higher energy structure (5b) had near Cs symmetry and generally good agreement with the experimental structure. The calculated UV-Vis and IR spectra of complex 5 are in excellent agreement with experiment. © 2012 Elsevier Ltd. All rights reserved.

Yerel Dokusunu Yitirmekte Olan Bir Kent: Malatya A City Losing Its Local Texture: Malatya

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Zaliha İnci KARABACAK

2013-07-01

ışı, modern kentleşme politikaları, ekonomik çıkarlar gibi çeşitli nedenlerle dönüşüme uğramaktadırlar. Bazı durumlarda, kentin çehresinde meydana gelen değişim kentin özüne zarar vermektedir. Günümüzde değişim bu yönüyle birçok şehirde etkisini göstermektedir. Bu durum ülkemizdeki birçok kentin yerel dokusunu kaybetmesine neden olmaktadır. Malatya; ekonomik, coğrafi, sosyal ve kültürel birtakım özellikleri ile öne çıkan bir şehirdir. Ancak bu ayırt edici değerlerin önemli bir bölümü değişime yenik düşmektedir. Bu bağlamda çalışmada, özellikle kente dünya çapında ekonomik bir değer kazandıran kayısı meyvesinin yetiştiği yeşil alanların ve kentin yerel mimari dokusunu oluşturan geleneksel Malatya evlerinin modern bir kent oluşturmak adına kente eklemlenen bulvar, kavşak, çok katlı konutlar gibi yapıların inşasında yaşadığı yaprak dökümü üzerinde durulmaktadır. Malatya’nın yitirmekte olduğu bu değerler, şehirde yakın tarihte çekilen bazı fotoğraflar aracılığıyla görsel olarak da ifade edilmektedir. Çalışmada, gündelik şehir yaşamında birçoğumuzun sıkça karşılaşarak içselleştirdiği benzeri değişimler Malatya örneği ile bir kez daha gündeme getirilmektedir. Böylece birey ve yurttaş olarak bu değişimlere daha duyarlı olma bilinci uyandırılmaya çalışılmaktadır.

27 Mayıs Darbesi Sonrası Celal Bayar ve Eski Demokrat Partililerin Türk Siyasi Hayatına Etkileri Ss, 2585-2598 The Effects of Celal Bayar and Former-Democratic Party Members on Turkish Political Life After the Coup of 27th May

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Nedim YALANSIZ

2012-09-01

Demokrat Parti iktidarına karşı yapıldı. Çok partili hayatın diğer aktörleri olan Cumhuriyet Halk Partisi ve Cumhuriyetçi Köylü Millet Partisi siyasi faaliyetlerine devam ederken, Demokrat Parti bu haktan mahrum edildi. Darbe sonrası içlerinde Başbakan, bakanlar, milletvekilleri, il ve ilçe yöneticileri olmak üzere yaklaşık 500 Demokrat Parti üyesi tutuklandı. Yüksek Adalet Divanı adında bir yüksek mahkeme oluşturuldu. Bu mahkeme bir yıl süren yargılama süreci sonrasında Demokrat Parti üyelerine ölüm cezası ve müebbet hapis de dahil çeşitli cezalar verdi. Ölüm cezasına ve müebbet hapse çarptırılmış eski DP’li Cumhurbaşkanı, bakan, milletvekili ve yönetici, eski Demokrat Parti tabanının zorlaması, memleketin normalleşme ihtiyacı ve aflarından siyasi rant bekleyen yeni ve eski partilerin çabaları sonucu birkaç yıl sonra ağır cezalarından affedildiler. Bazıları da sağlık sorunları nedeniyle daha önce salıverilmişti. Özgürlüklerine kavuştuktan sonra da bu defa kendileri siyasi haklarını, iade-i itibarlarını elde etme mücadelesi verdiler. Ölüm ve hapis cezalarından kurtulmalarına rağmen, siyasi partilere üye olma, milletvekili seçilme hakları ve hatta siyasette yer almadan önce sahip oldukları mesleklerini(örneğin doktorluk gibi yapabilme hakları ellerinden alınmıştı. İktidar ve muhalefet partilerinin anlaşmaları sonucu çıkarılan siyasi aflarla önce mesleklerini yapabilme hakları, sonra siyasi haklarını elde ettiler. Araya 12 Mart ve 12 Eylül darbelerinin girmesiyle bu çok zorlu ve uzun bir süreçte gerçekleşti. Eski DP’liler siyasi haklarını elde etme yanında merkez sağı yeniden Demokrat Parti çatısı altında birleştirmeyi hedeflediler. Kendilerinden koparak kurulan yeni ve güçlü partilerin ve bunların yeni kuşak seçmenlerinin olması nedeniyle bu hedefleri istedikleri şekilde gerçekleşmedi. Bu makalede eski DP’lilerin bu mücadeleleri anlatılmaktadır.

1929 Dünya Ekonomi Krizi Ve Ulusal Ekonomiyi Güçlendirme Mücadelesinde Kadınlar The Impact Of 1929 World Economic Crisis On Turkey And Women In Bolstering National Economy

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Doğan DUMAN

2013-07-01

Full Text Available After the independence war, Turkey went through some radicalpolitical and legal amendments. Despite the worst picture in economy,Turkey obtained significant successes as a result of the exuberance ofthe new Republic. However, the crisis which broke out first in the USAand then spread to the other capitalistic countries and which wasconsidered as the first major global crisis shook and had its deepreverberations in Turkey. The first impact was the devaluation of theTurkish currency. Secondly, the prices in theagriculture field droppedand affected the economy radically.Like many nations in a similar situation, Turkey planned toundergo a new economic policy and initiated a self sustaining policy.Hence, new measures were taken to encourage the nation to consumethe local products and to start saving. As a result, to implement thepolicy to use the local produce and to save as possible, a lot ofcampaigns were launched. Turkish women had a special mission in thisstruggle. Women who started to take their place sociallyandeconomically in the modernization process in Republic, had anactive role to bolster the national economy. This study aims athighlighting the major causes of the crisis, the impact on Turkisheconomy and the place of women in this struggle to overcome the crisis. Bağımsızlık savaşının kazanılmasından sonra Türkiye’de öncelikle köklü siyasal ve hukuksal değişiklikler gerçekleştirildi. Ekonomi alanında devralınan olumsuz tabloya rağmen ise, yeni bir devlet kurmanın verdiği coşkuyla ekonomik alanda da küçümsenmeyecek başarılar elde edildi. Fakat 1920’lerin sonunda önce Amerika Birleşik Devletleri’nde daha sonra diğer büyük kapitalist ülkelerde ortaya çıkan ve kapitalist dünyanın ilk büyük ekonomi krizi olarak nitelendirilen 1929 Dünya Ekonomi Krizi Türkiye’yi de derinden sarstı. Krizin Türkiye’ye ilk yansıması Türk lirasının hızlı bir değer kaybına uğraması şeklinde oldu. Ard

Metallation of N-allenylpyrroles by superbase reagents. Synthesis of new N-substituted pyrroles

International Nuclear Information System (INIS)

Tarasova, O.A.; Brandsma, L.; Verkrajsse, Kh.D.; Mal'kina, A.G.; Trofimov, B.A.

1996-01-01

Metallation of N-allenylpyrrole by BuLi-Et 2 O (THP), BuLi-t-BuOK-THP superbases and reactions of carbanions formed with different electrophilic agents have been studied. Fundamental data on mutual influence of allene group and pyrrole ring have been obtained. Alpha-proton features the highest acidity and it is the first one to be replaced by metal. In BuLi excess (more than 3-fold) in ether or in BuLi-t-BuOK-THP system a through metallation of allene group occurs. New pyrroles functionally substituted in allene chain have been prepared. 19 refs.; 3 tabs

Klientu attiecību pārvaldes sistēmas ieviešana IT uzņēmumā un pielāgošana tā biznesa vajadzībām

OpenAIRE

Šmitenbergs, Oskars

2006-01-01

Bakalaura darbs „Klientu attiecību pārvaldes sistēmas ieviešana IT uzņēmumā un pielāgošana tā biznesa vajadzībām” ir sistēmas Microsoft Dynamics™ CRM 3.0 ieviešanas procesa apraksts IT uzņēmumā SIA „UNITREE”. Darbs sniedz ieskatu sistēmas ieviešanas nepieciešamības cēloņos vidēja lieluma un lielos uzņēmumos. Kā viena no problēmu cēloņu novēršanas iespējām tiek piedāvāta Microsoft Dynamics™ CRM 3.0 ieviešana uzņēmumā, tāpēc darbā galvenokārt tiek apskatīta biznesa pārvaldības iespējas, izmanto...

Risk assessment of occupational radiation dose at the teletherapy facility of the Korle-Bu Teaching Hospital, Ghana

International Nuclear Information System (INIS)

Gollo, Selasie Richie Valens Kweku

2016-07-01

The National centre for Radiotherapy and Nuclear Medicine at the Korle-bu Teaching Hospital in Ghana uses a Theratron Equinox 100 Cobalt-60 teletherapy machine that was commissioned in 2014 with a source activity of 370.4TBq. The prime objective of this research was to estimate the risk and probability of cancer induction to workers and also to evaluate the level of radiation safety at the facility. Data was collected by means of TLDs and personal dose records available between the periods February 2010 and April 2016. The results from 2010-2016 were used to compute the mean annual dose, mean annual collective dose as well as risk assessments using the ICRP 1990 and 2007 recommendations. Ambient dose rate measurements were also done using a Thermo electron survey meter. The Results showed that mean effective dose recorded from TLDs used in this research ranged from 0.08mSv-0.36mSv whiles dose records from 2010-2016 showed mean annual effective doses ranged between 0.23mSv-0.65mSv. Mean annual collective dose was 0.09 mSv. Annual cancer risk estimates also showed that workers probability of developing cancers had a mean value of 2.37 x 10"-"2±7.75 x 10"-"3 whiles risk of passing hereditary traits to offspring born after exposure showed a mean value 3.96 x 10"-"3± 1.29 x 10"-"3 according to the ICRP 1990 recommendations and ICRP 2007 showed that possibility of cancer induction to workers showed a mean value of 2.03 x 10"-"2±1.61 x 10"-"3. Mean annual dose rates did not exceed 14.8mSv/a,5mSv/a and 0.74mSv/a for the treatment room, control console room and the controlled area respectively. This shows that workers at the facility are not likely to exceed the recommended dose limit within a year while working at the facility. Ambient dose rates did not exceed 7.39μSv/hr, 2.80μSv/hr and 0.37μSv/hr for the treatment room, control console room and the controlled area respectively. These values obtained are below the recommended limit of 20μSv/hr. (au)

Economic and clinical aspects of intravenous versus oral busulfan in adult patients for conditioning prior to HSCT.

Science.gov (United States)

Berger, Karin; Schopohl, Dorothee; Rieger, Christina; Ostermann, Helmut

2015-12-01

Busulfan (BU) used as cytoreductive conditioning prior to hematopoietic stem cell transplantation (HSCT) is available as intravenous (IV) and oral (O) preparation. IV-BU has clinical advantages associated with relevant incremental costs. The aim was to determine the economic impact of IV-BU versus O-BU in adult HSCT recipients from a German health care providers' perspective. A budget-impact model (BIM) including costs and risks for oral mucositis (OM), infection with OM, and hepatic sinusoidal obstruction syndrome (SOS) was developed. Model inputs are literature data comparing clinical effects of IV-BU versus O-BU and German cost data (conditioning therapy, treatment of OM, infections, SOS without/with multiorgan failure) from literature and tariff lists. Base case calculations resulted the following: total costs of adverse events were €86,434 with O-BU and €44,376 with IV-BU for ten patients each. Considering costs of adverse events and drugs, about €5840 for ten patients receiving IV-BU are saved. Sensitivity analyses were conducted in several ways. Cost savings range between €4910 and €12,640 per ten patients for all adverse events and €2070 or €1140 per ten patients considering SOS only. Drug treatment of SOS and treatment of multiorgan failure during severe SOS are major cost drivers. Worst case scenario calculations (assuming -25% risk of all adverse events for O-BU and +25% for IV-BU) yield up to €27,570 per ten patients with IV-BU. Considering costs of adverse events and drugs, IV-BU is the dominant alternative from a German providers' perspective. For more comprehensive economic evaluations, additional epidemiological data, evidence on clinical outcomes, patient-reported outcomes, and treatment patterns are needed.

Buruli Ulcer Disease and Its Association with Land Cover in Southwestern Ghana.

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Jianyong Wu

2015-06-01

Full Text Available Buruli ulcer (BU, one of 17 neglected tropical diseases, is a debilitating skin and soft tissue infection caused by Mycobacterium ulcerans. In tropical Africa, changes in land use and proximity to water have been associated with the disease. This study presents the first analysis of BU at the village level in southwestern Ghana, where prevalence rates are among the highest globally, and explores fine and medium-scale associations with land cover by comparing patterns both within BU clusters and surrounding landscapes.We obtained 339 hospital-confirmed BU cases in southwestern Ghana between 2007 and 2010. The clusters of BU were identified using spatial scan statistics and the percentages of six land cover classes were calculated based on Landsat and Rapid Eye imagery for each of 154 villages/towns. The association between BU prevalence and each land cover class was calculated using negative binomial regression models. We found that older people had a significantly higher risk for BU after considering population age structure. BU cases were positively associated with the higher percentage of water and grassland surrounding each village, but negatively associated with the percent of urban. The results also showed that BU was clustered in areas with high percentage of mining activity, suggesting that water and mining play an important and potentially interactive role in BU occurrence.Our study highlights the importance of multiple land use changes along the Offin River, particularly mining and agriculture, which might be associated with BU disease in southwestern Ghana. Our study is the first to use both medium- and high-resolution imagery to assess these changes. We also show that older populations (≥ 60 y appear to be at higher risk of BU disease than children, once BU data were weighted by population age structures.

Induced mutations for soybean rust resistance

International Nuclear Information System (INIS)

Smutkupt, S.; Wongpiyasatid, A.; Lamseejan, S.

1983-01-01

Soybean mutation experiments for inducing rust resistance in the cultivars G 8375, Wakashima mutant number 10, Taichung N, S.J.2, S.J.4, BM 50, BM 98, G 8377, G 8586 and G 8587 have been carried out since 1979. Six pods from each of 4438 control and 43,907 M 1 plants were randomly harvested. M 2 seeds of each cultivar of different doses were bulked (M 2 bulk). In addition, 270 good M 1 plants were selected and threshed singly (M 2 single). M 2 -bulk and M 2 -single seeds were advanced to M 3 . Both, M 3 -bulk and M 3 -single plants, together with the remaining M 2 -bulk seeds were screened for rust resistance in the rainy season of 1980 in Nong Hoi Valley (altitude about 1000 m above sea level) and at Mae Joe Station, both in Chiang Mai Province (latitude 18 deg. 31'-19 deg. N). Based on the IWGSR rating system, soybean plants with slow growth of rust were selected from both locations. The results were as follows: Six plants were selected from a total of 2802 control plants, and 115 from a total of 28,834 M 2 and M 3 plants. Further evaluation of these selections for rust resistance will be carried out in the rainy season of 1981 in Nong Hoi Valley, Chiang Mai. (author)

Safety analysis report - packages 9965, 9968, 9972-9975 packages

International Nuclear Information System (INIS)

Van Alstine, M.N.

1997-10-01

This Safety Analysis Report for Packaging (SARP) documents the performance of the 9965 B( ), 9968 B( ), 9972 B(U), 9973 B(U), 9974 B(U), and 9975 B(U) packages in satisfying the regulatory safety requirements of the Code of Federal Regulations (CFR) 10 CFR 71 and the International Atomic Energy Agency (IAEA) Safety Series No. 6, Regulations for the Safe Transport of Radioactive Material, 1985 edition. Results of the analysis and testing performed on the 9965 B(), 9968 B(), 9972 B(U), 9973 B(U), and 9975 B(U) packages are presented in this SARP, which was prepared in accordance with U.S. Department of Energy (DOE) Order 5480.3 and in the format specified in the Nuclear Regulatory Commission (NRC) Regulatory Guides 7.9 and 7.10

TECHNICAL COORDINATION,SCHEDULE AND INTEGRATION

CERN Document Server

A. Ball

A pivotal milestone in CMS underground installation will be reached during this CMS week when the 1920 ton central wheel (YB0) of the iron yoke is lowered into the experimental cavern on Wednesday 28 February. This milestone will be reached on the on the date planned due to the hard work and dedication of many people, on the surface, underground and at supporting sites. Details of the programme for 28 February, visit opportunities and progress updates, can be found on the TC web pages on iCMS. http://cms.cern.ch/iCMS/jsp/page.jsp?mode=cms&ac-tion=url&urlkey=CMS_TC Heavy lowering The build-up to the above event started shortly after the December CMS week, when the YE+2 endcap disk was safely lowered into the cavern, followed by the YE+1 on January 9. The lowering of YE+1 was the most complicated so far because, due to the calorimetry nose, the centre of gravity lies outside the plane of the disk. However, after 10 hours it touched-down safely without any problems. On Jan. 19 the first barrel wheel ...

Wrestling: An Integral Part of Iranian Fighting Arts

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Manouchehr Moshtagh Khorasani

2012-07-01

Full Text Available Wrestling played and has been playing a very important role in Iranian cultural heritage. First, the present article discusses the terms and different uses of wrestling techniques be it in unarmed duels or in combination with weapons. Then, three relevant manuscripts will be analyzed such as an untitled wrestling manuscript by an anonymous author from the period of Šāh Esmāil Safavid (1502-1524 C.E., the manuscript Tumār-e Puryā-ye Vali also written by an anonymous author during the Safavid period (1502-1722 C.E. and the work by a famous poet named Mirnejāt with the title Masnavi-ye Golkošti-ye Mirnejāt that was written towards the end of the period of Šāh Soleymān Safavid (1666-1694 C.E. or the beginning of the period of Šāh Soltān Hosseyn Safavid (1694-1722 C.E.. Based on some terms and descriptions of the techniques found in these manuscripts, it is possible to appreciate how traditional forms of wrestling in Iran have preserved some of these techniques.