WorldWideScience

Sample records for non-trade secret notice

  1. 40 CFR 350.18 - Release of chemical identity determined to be non-trade secret; notice of intent to release...

    Science.gov (United States)

    2010-07-01

    ... determined to be non-trade secret; notice of intent to release chemical identity. 350.18 Section 350.18... INFORMATION: AND TRADE SECRET DISCLOSURES TO HEALTH PROFESSIONALS Trade Secrecy Claims § 350.18 Release of chemical identity determined to be non-trade secret; notice of intent to release chemical identity. (a...

  2. Trade Secrets in Life Science and Pharmaceutical Companies

    Science.gov (United States)

    Nealey, Tara; Daignault, Ronald M.; Cai, Yu

    2015-01-01

    Trade secret protection arises under state common law and state statutes. In general, a trade secret is information that is not generally known to the public and is maintained as a secret, and it provides a competitive advantage or economic benefit to the trade secret holder. Trade secrets can be worth tens or hundreds of millions of dollars, and damage awards in trade secret litigation have been high; often, there is a lot at stake. Obtaining a trade secret through “improper means” is misappropriation. If the alleged trade secret, however, was developed independently, known publicly, or not maintained as a secret, then those defenses may successfully overcome a claim for trade secret misappropriation. With today’s interconnectedness in the biotechnology and pharmaceutical fields, more collaborations, joint ventures, and outsourcing arrangements among firms, and increased mobility of employees’ careers, life science companies need to not only understand how to protect their trade secrets, but also know how to defend against a claim for trade secret theft. PMID:25414378

  3. Trade secrets in life science and pharmaceutical companies.

    Science.gov (United States)

    Nealey, Tara; Daignault, Ronald M; Cai, Yu

    2014-11-20

    Trade secret protection arises under state common law and state statutes. In general, a trade secret is information that is not generally known to the public and is maintained as a secret, and it provides a competitive advantage or economic benefit to the trade secret holder. Trade secrets can be worth tens or hundreds of millions of dollars, and damage awards in trade secret litigation have been high; often, there is a lot at stake. Obtaining a trade secret through "improper means" is misappropriation. If the alleged trade secret, however, was developed independently, known publicly, or not maintained as a secret, then those defenses may successfully overcome a claim for trade secret misappropriation. With today's interconnectedness in the biotechnology and pharmaceutical fields, more collaborations, joint ventures, and outsourcing arrangements among firms, and increased mobility of employees' careers, life science companies need to not only understand how to protect their trade secrets, but also know how to defend against a claim for trade secret theft. Copyright © 2015 Cold Spring Harbor Laboratory Press; all rights reserved.

  4. Some Economics of Trade Secret Law

    OpenAIRE

    David D. Friedman; William M. Landes; Richard A. Posner

    1991-01-01

    Despite the practical importance of trade secrets to the business community, the law of trade secrets is a neglected orphan in economic analysis. This paper sketches an approach to the economics of trade secret law that connects it more closely both to other areas of intellectual property and to broader issues in the positive economic theory of the common law.

  5. Employees, Trade Secrets and Restrictive Covenants

    NARCIS (Netherlands)

    Kamperman Sanders, Anselm; Heath, C.

    2017-01-01

    The book covers the protection of trade secrets and the law on post-contractual non-compete clauses (restrictive covenants) in an employment context. The topic is approached on an international and comparative level (chapters 1–3 and 10), and by way of country reports covering several European and

  6. 29 CFR 1903.9 - Trade secrets.

    Science.gov (United States)

    2010-07-01

    ... INSPECTIONS, CITATIONS AND PROPOSED PENALTIES § 1903.9 Trade secrets. (a) Section 15 of the Act provides: “All... concerns or relates to the trade secrets, processes, operations, style of work, or apparatus, or to the...

  7. The problem of using trade secrets in economic relations

    Directory of Open Access Journals (Sweden)

    А. О. Олефір

    2015-05-01

    . The objects of trade secrets, depending on the fields may be the following types of information: (1 scientific and technical; (2 management; (3 commercial; (4 financial. At this stage, there is a growing role of know-how, compared with patents, because as their special advantages and drop interest in patenting innovations as an independent factor, as well as economic and legal efficiency mode of trade secrets. Under the know-how necessary to understand the technical, manufacturing, engineering knowledge, experience and skills related to the design, development, manufacture, sale, operation, maintenance, repair, improve technology and other innovative objects which have the status of trade secrets, and a factor of competitiveness entity. Given the fact that the administrative and jurisdictional mechanisms for the protection of trade secrets are more or less clear, we focused on internal corporate events. First, this is consolidation in the basic documents of the entity (statute, founding and collective agreements, work rules on trade secret law such provision as law on ownership and protection of trade secrets. Second, the order of the head of the entity to approve the list of information to be protected as a trade secret. Third, develop and adopt regulations on trade secrets. Fourth, to approve the regulations on the organization of the documents containing trade secrets. Fifth, to include in a labor agreement (contract the condition of non-disclosure of trade secrets or employee expected signing of enhancing privacy protection. Conclusions of the research. In order to stimulate innovation growth and protection of corporate security entities we should propose changes to the legislation: (1 secure the definition of the concept of «know-how (secret production» indicating that the exclusive right to the secret of acting as long as the relation of production secrets operating mode of trade secrets; (2 add Tax Code of Ukraine following types of tax benefits: (a exemption

  8. 42 CFR 405.215 - Confidential commercial and trade secret information.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Confidential commercial and trade secret information. 405.215 Section 405.215 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF... trade secret information. To the extent that CMS relies on confidential commercial or trade secret...

  9. Trade Secrets in the Legal Studies Curriculum--A Case Study

    Science.gov (United States)

    Evans, Michelle

    2012-01-01

    Trade secrets can be a valuable company asset because of their potential to last forever. Unfortunately, along with such a significant benefit, there is also a significant risk--the risk that the trade secret can be lost in an instant if it is not sufficiently protected. Companies must be vigilant in protecting these secrets. However, the law is…

  10. 40 CFR 370.64 - What information can I claim as trade secret or confidential?

    Science.gov (United States)

    2010-07-01

    ... secret or confidential? 370.64 Section 370.64 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... secret or confidential? (a) Trade secrets. You may be able to withhold the name of a specific chemical... trade secret. The requirements for withholding trade secret information are set forth in EPCRA section...

  11. 77 FR 34037 - Agency Information Collection Activities; Proposed Collection; Comment Request; Trade Secret...

    Science.gov (United States)

    2012-06-08

    ... Activities; Proposed Collection; Comment Request; Trade Secret Claims for Emergency Planning and Community... Planning and Community Right-to- Know Act (EPCRA). Title: Trade Secret Claims for Emergency Planning and...). Estimated total number of potential respondents: 481. Frequency of response: Trade secret claims are...

  12. Growth of Non-bank Trade Finance

    OpenAIRE

    Satinder Bhatia

    2017-01-01

    The rise of non-bank trade finance has been especially noticeable in the last decade. Many commodity and e-commerce companies are rapidly entering this arena as sovereign guarantees and collaterals take a backseat making it harder for banks to apply traditional models while lending to businesses. Non-banks which are more nimble occupy space vacated by banks. Increasingly, though, banks have begun to collaborate with non-banks, particularly fintech companies for rapid processi...

  13. EPCRA Trade Secret Form Instructions (PDF)

    Science.gov (United States)

    Detail on what information is required for each section of the form. Only the specific chemical identity required to be disclosed in EPCRA sections 303, 311,312, and 313 submissions may be claimed trade secret on the EPCRA report.

  14. A trade secret model for genomic biobanking.

    Science.gov (United States)

    Conley, John M; Mitchell, Robert; Cadigan, R Jean; Davis, Arlene M; Dobson, Allison W; Gladden, Ryan Q

    2012-01-01

    Genomic biobanks present ethical challenges that are qualitatively unique and quantitatively unprecedented. Many critics have questioned whether the current system of informed consent can be meaningfully applied to genomic biobanking. Proposals for reform have come from many directions, but have tended to involve incremental change in current informed consent practice. This paper reports on our efforts to seek new ideas and approaches from those whom informed consent is designed to protect: research subjects. Our model emerged from semi-structured interviews with healthy volunteers who had been recruited to join either of two biobanks (some joined, some did not), and whom we encouraged to explain their concerns and how they understood the relationship between specimen contributors and biobanks. These subjects spoke about their DNA and the information it contains in ways that were strikingly evocative of the legal concept of the trade secret. They then described the terms and conditions under which they might let others study their DNA, and there was a compelling analogy to the commonplace practice of trade secret licensing. We propose a novel biobanking model based on this trade secret concept, and argue that it would be a practical, legal, and ethical improvement on the status quo. © 2012 American Society of Law, Medicine & Ethics, Inc.

  15. 40 CFR 350.15 - Public petitions requesting disclosure of chemical identity claimed as trade secret.

    Science.gov (United States)

    2010-07-01

    ... of chemical identity claimed as trade secret. 350.15 Section 350.15 Protection of Environment... TRADE SECRECY CLAIMS FOR EMERGENCY PLANNING AND COMMUNITY RIGHT-TO-KNOW INFORMATION: AND TRADE SECRET... chemical identity claimed as trade secret. (a) The public may request the disclosure of chemical identity...

  16. Trading secrets: Jews and the early modern quest for clandestine knowledge.

    Science.gov (United States)

    Jütte, Daniel

    2012-12-01

    This essay explores the significance and function of secrecy and secret sciences in Jewish-Christian relations and in Jewish culture in the early modern period. It shows how the trade in clandestine knowledge and the practice of secret sciences became a complex, sometimes hazardous space for contact between Jews and Christians. By examining this trade, the essay clarifies the role of secrecy in the early modern marketplace of knowledge. The attribution of secretiveness to Jews was a widespread topos in early modern European thought. However, relatively little is known about the implications of such beliefs in science or in daily life. The essay pays special attention to the fact that trade in secret knowledge frequently offered Jews a path to the center of power, especially at court. Furthermore, it becomes clear that the practice of secret sciences, the trade in clandestine knowledge, and a mercantile agenda were often inextricably interwoven. Special attention is paid to the Italian-Jewish alchemist, engineer, and entrepreneur Abramo Colorni (ca. 1544-1599), whose career illustrates the opportunities provided by the marketplace of secrets at that time. Much scholarly (and less scholarly) attention has been devoted to whether and what Jews "contributed" to what is commonly called the "Scientific Revolution." This essay argues that the question is misdirected and that, instead, we should pay more attention to the distinctive opportunities offered by the early modern economy of secrecy.

  17. Trade Secret Law and Information Systems: Can Your Students Keep a Secret?

    Science.gov (United States)

    Willey, Lorrie; Ford, Janet C.; White, Barbara Jo; Clapper, Danial L.

    2011-01-01

    The impact of intellectual property (IP) law on information systems (IS) professionals in business cannot be overstated. The IS 2010 model curriculum guidelines for undergraduate IS programs stress the importance of information security and knowledge about IP. While copyright and patents are the most well-known types of IP, another, trade secrets,…

  18. The trade secrets protection in U.S. and in Europe: a comparative study

    Directory of Open Access Journals (Sweden)

    Chiara Gaido

    2017-12-01

    Full Text Available Only by deeply understanding the new laws that govern trade secrets protection in the United States and Europe, companies will be able to effectively protect their own trade secrets. The purpose of this paper is to highlight the similarities and differences between both regulations to give useful guidelines to international companies who deal in both geographical areas. Therefore, the paper will focus first on the economic value of trade secrets and the costs related to cybercrime and cyberespionage. Then, it will analyze the US and EU historical legal backgrounds that brought to the adoption of both laws. Finally, this article will make a comparative analysis of the provisions in each law. Hence, the paper makes potential suggestions for companies that deal in both regimes.

  19. 我國侵害營業秘密與競業禁止違約判決之量化研究 Quantitative Analysis of the ROC Court Decisions on Trade Secret Infringements and Violation of Non-Compete Clauses

    Directory of Open Access Journals (Sweden)

    洪榮宗 Oliver Hung

    2007-12-01

    Full Text Available 營業秘密法生效迄今十年,其對於營業秘密的保護是否已周延?實有待觀察。又離職後競業禁止約款之相關實務運作現況為何?亦為探討營業秘密保護議題時,無法切割之問題。 本文利用司法院之系統查詢我國地方法院自1999 年8 月1 日起至2006年6 月30 日止,侵害營業秘密或違反競業禁止約款之民事判決,並以量化分析方式探討司法實務之態度。 本文之量化分析顯示:營業秘密與競業禁止訴訟之勝率均偏低;主張違反競業禁止明顯比主張侵害營業秘密來得容易;兩類訴訟之平均審理時間恐無法因應其急迫性需求;未約定違反競業禁止約款之違約賠償罰則的敗訴機率極高;競業禁止約款之五原則在法院實務上並未被遵守等。本文希望透過上開發現與確認,能期待找出改善之道。 The ROC Trade Secret Act has come into force for 10 years. However, whether it has sufficiently protected the trade secrets remains unanswered. In addition, the current operation and practice of “Non-Compete Clauses after Employment Relationship” are also important issues while discussing the trade secrets issues. Through the database of the ROC Judicial Yuan, we reviewed all the cases in the ROC district courts in connection with infringements on trade secrets and breach of non-compete clauses from August 1, 1999 to June 30, 2006 and conducted quantitative analysis of the courts’ opinions in this regard. The results of our quantitative analysis show that: 1. most of the decisions related to trade secret infringements and breach of non-compete clauses are in favor of defendants; 2. it is easier to claim violation of the non-compete clauses than infringements on trade secrets; 3. the trial period is too long to protect the plaintiffs given that the time is of essence; 4. it is quite probable that plaintiffs will lose the lawsuits if no penalty clause for

  20. Open Secrets

    OpenAIRE

    Madison, Michael

    2017-01-01

    The law of trade secrets is often conceptualized in bilateral terms, as creating and enforcing rights between trade secret owners, on the one hand, and misappropriators on the other hand. This paper, a chapter in a forthcoming collection on the law of trade secrets, argues that trade secrets and the law that guards them can serve structural and insitutional roles as well. Somewhat surprisingly, given the law’s focus on secrecy, among the institutional products of trade secrets law are commons...

  1. 76 FR 26579 - Procedures for Submitting to the Department of Energy Trade Secrets and Commercial or Financial...

    Science.gov (United States)

    2011-05-09

    ... assistance can take the form of financial assistance (i.e., grants, cooperative agreements, and technology... Department of Energy Trade Secrets and Commercial or Financial Information That Is Privileged or Confidential... of trade secrets and commercial or financial information that is privileged or confidential, where...

  2. The limitations of contractual clauses to determine the legal nature of information and to protect trade secrets

    Directory of Open Access Journals (Sweden)

    Nelson Remolina Angarita

    2017-12-01

    Full Text Available This text analyses the legal requirements for information to be considered a trade secret based on Colombian regulations and rulings issued by the Superintendencia de Industria y Comercio. A contractual clause, by itself, does not have the power to define the information that can be considered a trade secret because freedom of choice cannot disregard the legal nature of the information.

  3. 21 CFR 20.61 - Trade secrets and commercial or financial information which is privileged or confidential.

    Science.gov (United States)

    2010-04-01

    ... ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PUBLIC INFORMATION Exemptions § 20.61 Trade..., preparing, compounding, or processing of trade commodities and that can be said to be the end product of either innovation or substantial effort. There must be a direct relationship between the trade secret and...

  4. The Criminalization of the Theft of Trade Secrets:\\ud An Analysis of the Economic Espionage Act

    OpenAIRE

    Searle, Nicola

    2012-01-01

    This paper presents a law and economics assessment of how the elevation of the theft of trade secrets from civil malfeasance to a felony affects the incentives for both firms and potential thieves. The paper begins with theoretical analysis of the EEA and concludes with an empirical assessment of prosecutions under the EEA. In comparison to penalties used in civil cases, the new incentive of a criminal deterrent to trade secret theft introduces severe consequences, such as incarceration as a ...

  5. Non-preferential Trading Clubs

    DEFF Research Database (Denmark)

    Raimondos-Møller, Pascalis; Woodland, Alan D.

    2006-01-01

    This paper examines the welfare implications of non-discriminatory tariff reforms by a subset of countries, which we term a non-preferential trading club. We show that there exist coordinated tariff reforms, accompanied by appropriate income transfers between the member countries, that unambiguou......This paper examines the welfare implications of non-discriminatory tariff reforms by a subset of countries, which we term a non-preferential trading club. We show that there exist coordinated tariff reforms, accompanied by appropriate income transfers between the member countries...

  6. 76 FR 48145 - North American Free-Trade Agreement, Article 1904; Binational Panel Reviews: Notice of...

    Science.gov (United States)

    2011-08-08

    ... DEPARTMENT OF COMMERCE International Trade Administration North American Free-Trade Agreement.... SUPPLEMENTARY INFORMATION: Chapter 19 of the North American Free-Trade Agreement (``Agreement'') established a..., United States Section, International Trade Administration, Department of Commerce. ACTION: Notice of...

  7. Trade Facilitation Provisions in Regional Trade Agreements: Discriminatory or Non-discriminatory?

    Directory of Open Access Journals (Sweden)

    Innwon Park

    2016-12-01

    Full Text Available The RTAs with trade facilitation provisions have been expected to generate a larger net trade-creating effect and complement the discriminatory feature of RTAs but have yet to be empirically proven. Recognizing the limitations of existing studies, we conducted a quantitative analysis on the effects of RTAs with and without trade facilitation provisions on both intra- and extra-bloc trade by using a modified gravity equation. We applied the Poisson Pseudo-Maximum Likelihood (PPML estimation with time varying exporter and importer fixed effect method to panel data consisting of 45,770 country pairs covering 170 countries for 2000-2010. We found that the trade facilitation provisions in existing RTAs are non-discriminatory by generating more intra- and extra-bloc trade in general. In particular, we found that the trade effects of RTAs in the APEC region are much stronger than the general case covering all RTAs in the world. In addition, as we control the trade effect of a country's trade facilitation, which is ranked by the World Bank's logistic performance index, RTAs consisting of trade facilitation provisions are discriminatory for trade in final goods and non-discriminatory for trade in intermediate goods. Overall, we endeavor to "explain," instead of "hypothesizing," why most of the recent RTAs contain trade facilitation provisions, especially in light of the deepening regional interdependence through trade in parts and components under global value chains and support the necessity of multilateralizing RTAs by implementing non-discriminatory trade facilitation provisions.

  8. 76 FR 23286 - North American Free Trade Agreement (NAFTA), Article 1904 Binational Panel Reviews: Notice of...

    Science.gov (United States)

    2011-04-26

    ... DEPARTMENT OF COMMERCE International Trade Administration North American Free Trade Agreement... Secretariat, United States Section, International Trade Administration, Department of Commerce. ACTION: Notice... International Trade Commission, in the matter of Light-Walled Rectangular Pipe and Tube from Mexico, Secretariat...

  9. Cigarette company trade secrets are not secret: an analysis of reverse engineering reports in internal tobacco industry documents released as a result of litigation.

    Science.gov (United States)

    Velicer, Clayton; Lempert, Lauren K; Glantz, Stanton

    2015-09-01

    Use previously secret tobacco industry documents to assess tobacco companies' routine claims of trade secret protection for information on cigarette ingredients, additives and construction made to regulatory agencies, as well as the companies' refusal to publicly disclose this information. We analysed previously secret tobacco industry documents available at (http://legacy.library.ucsf.edu) to identify 100 examples of seven major tobacco companies' reverse engineering of their competitors' brands between 1937 and 2001. These reverse engineering reports contain detailed data for 142 different measurements for at least two companies, including physical parameters of the cigarettes, tobacco types, humectants, additives, flavourings, and smoke constituents of competitors' cigarettes. These 100 documents were distributed to 564 employees, including top managers in domestic and foreign offices across multiple departments, including executive leadership, research and design, product development, marketing and legal. These documents reported new competitors' products, measured ingredient changes over time, and informed companies' decisions regarding ingredients in their own products. Because cigarette companies routinely analyse their competitors' cigarettes in great detail, this information is neither secret nor commercially valuable and, thus, does not meet the legal definition of a 'trade secret.' This information is only being kept 'secret' from the people consuming cigarettes and the scientific community. Public agencies should release this detailed information because it would provide valuable information about how ingredients affect addictiveness and toxicity, and would help the public health community and consumers better understand the impact of cigarette design on human health. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  10. Independent consultants : fiduciary duties, trade secrets and confidential information

    International Nuclear Information System (INIS)

    Fraser, B.; Wilhelmson, M.

    1999-01-01

    Because of cutbacks and downsizing within the petroleum industry, it has become one of the largest users of contract personnel to provide services that were previously provided by senior levels of management. This paper explored the application of common law fiduciary duties and the duty of confidence to the independent workforce. It examined to what extent fiduciary duties apply to independent consultants and the best way for the employer to protect itself from the potential misuse of confidential information. Part 1 of the paper described fiduciary duties. A fiduciary relationship was described as one that possesses the following three characteristics: (1) the fiduciary has scope for the exercise of some discretion of power, (2) the fiduciary can unilaterally exercise that power to affect the beneficiary's practical interests, and (3) the beneficiary is peculiarly vulnerable to the fiduciary holding the discretion of power. Three examples of how the courts treated some arguments regarding fiduciaries were presented. Part 2 of this paper discussed how trade secrets and confidential information should be handled. It was explained, that regardless of fiduciary duties, the unauthorized use of confidential information by an independent contractor can give rise to liability and an award of damages by the courts. Some examples where the Supreme Court of Canada found breach of confidence by a party were presented. Information communicated from an employer to an employee can be divided into the following three categories: (1) publicly accessible and not confidential, (2) confidential and must be treated as such while an employee is employed, but if learned becomes part of the employees skill and knowledge, and (3) specific confidential trade secrets that cannot lawfully be used for anyone's benefit but the employer's. Issues regarding defining rights and obligations by contract were also discussed

  11. Are Preferential Trade Agreements with Non-trade Objectives a Stumbling Block for Multilateral Liberalization?

    OpenAIRE

    Nuno Limão

    2007-01-01

    In many preferential trade agreements (PTAs), countries exchange not only reductions in trade barriers but also cooperation in non-trade issues such as labour and environmental standards, intellectual property, etc. We provide a model of PTAs motivated by cooperation in non-trade issues and analyse its implications for global free trade and welfare. We find that such PTAs increase the cost of multilateral tariff reductions and thus cause a stumbling block to global free trade. This occurs bec...

  12. The constitutional protection of trade secrets and patents under the Biologics Price Competition and Innovation Act of 2009.

    Science.gov (United States)

    Epstein, Richard A

    2011-01-01

    The Biologics Price Competition and Innovation Act of 2009 ("Biosimilars Act") is for the field of pharmaceutical products the single most important legislative development since passage of the Drug Price Competition and Patent Term Restoration Act of 1984 ("Hatch-Waxman Act"), on which portions of the Biosimilars Act are clearly patterned. Congress revised section 351 of the Public Health Service Act (PHSA) to create a pathway for FDA approval of "biosimilar" biological products. Each biosimilar applicant is required to cite in its application a "reference product" that was approved on the basis of a full application containing testing data and manufacturing information, which is owned and was submitted by another company and much of which constitutes trade secret information subject to constitutional protection. Because the Biosimilars Act authorizes biosimilar applicants to cite these previously approved applications, the implementation of the new legislative scheme raises critical issues under the Fifth Amendment of the Constitution, pursuant to which private property--trade secrets included--may not be taken for public use, without "just compensation." FDA must confront those issues as it implements the scheme set out in the Biosimilars Act. This article will discuss these issues, after providing a brief overview of the Biosimilars Act and a more detailed examination of the law of trade secrets.

  13. 48 CFR 52.225-12 - Notice of Buy American Act Requirement-Construction Materials Under Trade Agreements.

    Science.gov (United States)

    2010-10-01

    ... Requirement-Construction Materials Under Trade Agreements. 52.225-12 Section 52.225-12 Federal Acquisition...—Construction Materials Under Trade Agreements. As prescribed in 25.1102(d)(1), insert the following provision: Notice of Buy American Act Requirement—Construction Materials Under Trade Agreements (FEB 2009) (a...

  14. 78 FR 73552 - National Institute on Deafness and Other Communication Disorders; Notice of Meeting

    Science.gov (United States)

    2013-12-06

    ... Deafness and Other Communication Disorders; Notice of Meeting Pursuant to section 10(d) of the Federal... Deafness and Other Communication Disorders Advisory Council. The meeting will be open to the public as.... The grant applications and the discussions could disclose confidential trade secrets or commercial...

  15. 78 FR 66946 - National Institute on Deafness and Other Communication Disorders; Notice of Closed Meeting

    Science.gov (United States)

    2013-11-07

    ... Deafness and Other Communication Disorders; Notice of Closed Meeting Pursuant to section 10(d) of the... disclose confidential trade secrets or commercial property such as patentable material, and personal... Deafness and Other Communication Disorders Special Emphasis Panel; Hearing Clinical Trial Review. Date...

  16. 77 FR 50705 - National Institute on Deafness and Other Communication Disorders; Notice of Closed Meetings

    Science.gov (United States)

    2012-08-22

    ... Deafness and Other Communication Disorders; Notice of Closed Meetings Pursuant to section 10(d) of the... disclose confidential trade secrets or commercial property such as patentable material, and personal... Deafness and Other Communication Disorders Special Emphasis Panel, NIDCD P30 Review Meeting. Date...

  17. 75 FR 33817 - National Institute on Deafness and Other Communication Disorders; Notice of Closed Meeting

    Science.gov (United States)

    2010-06-15

    ... Deafness and Other Communication Disorders; Notice of Closed Meeting Pursuant to section 10(d) of the... disclose confidential trade secrets or commercial property such as patentable material, and personal... Deafness and Other Communication Disorders Special Emphasis Panel, Translational PAR. Date: July 8, 2010...

  18. 77 FR 5036 - National Institute on Deafness and Other Communication Disorders; Notice of Closed Meetings

    Science.gov (United States)

    2012-02-01

    ... Deafness and Other Communication Disorders; Notice of Closed Meetings Pursuant to section 10(d) of the... disclose confidential trade secrets or commercial property such as patentable material, and personal... Deafness and Other Communication Disorders Special Emphasis Panel; Affordable Hearing. Date: February 14...

  19. 77 FR 5032 - National Institute on Deafness and Other Communication Disorders; Notice of Closed Meeting

    Science.gov (United States)

    2012-02-01

    ... Deafness and Other Communication Disorders; Notice of Closed Meeting Pursuant to section 10(d) of the... disclose confidential trade secrets or commercial property such as patentable material, and personal... constitute a clearly unwarranted invasion of personal privacy. Name of Committee: Communication Disorders...

  20. 75 FR 10244 - TC Energy Trading, LLC; Supplemental Notice That Initial Market-Based Rate Filing Includes...

    Science.gov (United States)

    2010-03-05

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ER10-792-000] TC Energy Trading, LLC; Supplemental Notice That Initial Market- Based Rate Filing Includes Request for Blanket... proceeding of TC Energy Trading, LLC's application for market-based rate authority, with an accompanying rate...

  1. 75 FR 5782 - Noble Energy Marketing and Trade Corporation; Supplemental Notice That Initial Market-Based Rate...

    Science.gov (United States)

    2010-02-04

    ... Marketing and Trade Corporation; Supplemental Notice That Initial Market-Based Rate Filing Includes Request...-referenced proceeding of Noble Energy Marketing and Trade Corporation's application for market- based rate... electronic submission of protests and interventions in lieu of paper, using the FERC Online links at http...

  2. 77 FR 13153 - National Advisory Committee for Labor Provisions of U.S. Free Trade Agreements; Notice of Open...

    Science.gov (United States)

    2012-03-05

    ....S. Free Trade Agreements; Notice of Open Meeting AGENCY: Bureau of International Labor Affairs, U.S... meeting is to discuss the implementation of the labor provisions of the Free Trade Agreements, technical... of Free Trade Agreements (FTAs), a brief presentation on USDOL technical assistance efforts in FTA...

  3. 75 FR 51279 - National Institute on Deafness and Other Communication Disorders; Notice of Closed Meetings

    Science.gov (United States)

    2010-08-19

    ... Deafness and Other Communication Disorders; Notice of Closed Meetings Pursuant to section 10(d) of the... disclose confidential trade secrets or commercial property such as patentable material, and personal... Deafness and Other Communication Disorders Special Emphasis Panel, R24 RFA. Date: September 16, 2010. Time...

  4. 75 FR 33818 - National Institute on Deafness and Other Communication Disorders; Notice of Closed Meeting

    Science.gov (United States)

    2010-06-15

    ... Deafness and Other Communication Disorders; Notice of Closed Meeting Pursuant to section 10(d) of the... disclose confidential trade secrets or commercial property such as patentable material, and personal... Deafness and Other Communication Disorders Special Emphasis Panel; VSL--SEP Review. Date: June 14, 2010...

  5. Non-Preferential Trading Clubs

    DEFF Research Database (Denmark)

    Raimondos-Møller, Pascalis; Woodland, Alan D.

    2004-01-01

    , that unambiguouslyincrease the welfare of these countries while leaving the welfare ofnon-members unaltered. In terms of economic policy implications, our resultsshow that there exist regional, MFN-consistent arrangements that leadto Pareto improvements in world welfare.JEL code: F15.Keywords: Trading clubs, non...

  6. 77 FR 56233 - National Advisory Committee for Labor Provisions of U.S. Free Trade Agreements; Notice of Open...

    Science.gov (United States)

    2012-09-12

    ....S. Free Trade Agreements; Notice of Open Meeting AGENCY: Bureau of International Labor Affairs, U.S... meeting is to discuss the implementation of the labor provisions of Free Trade Agreements (FTAs... Advisory Committee Act (FACA), as amended, 5 U.S.C. App. 2, the Office of Trade and Labor Affairs (OTLA...

  7. 78 FR 13088 - National Advisory Committee for Labor Provisions of U.S. Free Trade Agreements; Notice of Open...

    Science.gov (United States)

    2013-02-26

    ....S. Free Trade Agreements; Notice of Open Meeting AGENCY: Bureau of International Labor Affairs, U.S... meeting is to discuss the implementation of the labor provisions of Free Trade Agreements, as well as a... implementation of the labor provisions of Free Trade Agreements, and a review and discussion by the full...

  8. Non-conventional provisions in regional trade agreements : do they enhance international trade?

    OpenAIRE

    Hayakawa, Kazunobu; Kimura, Fukunari; Nabeshima, Kaoru

    2011-01-01

    The scope of recent regional trade agreements (RTAs) is becoming much wider in terms of including several provisions such as competition policy or intellectual property. This paper empirically examines how far advanced, non-conventional provisions in RTAs increase trade values among RTA member countries, by estimating the gravity equation with more disaggregated indicators for RTAs. As a result, we find that the provision on competition policy has the largest impacts on trade values, followin...

  9. Long-term outcomes of surgery and radiotherapy for secreting and non-secreting pituitary adenoma

    International Nuclear Information System (INIS)

    Kim, Mi Young; Kim, Jin Hee; Oh, Young Kee; Kim, El

    2016-01-01

    To investigate treatment outcome and long term complication after surgery and radiotherapy (RT) for pituitary adenoma. From 1990 to 2009, 73 patients with surgery and RT for pituitary adenoma were analyzed in this study. Median age was 51 years (range, 25 to 71 years). Median tumor size was 3 cm (range, 1 to 5 cm) with suprasellar (n = 21), cavernous sinus extension (n = 14) or both (n = 5). Hormone secreting tumor was diagnosed in 29 patients; 16 patients with prolactin, 12 patients with growth hormone, and 1 patient with adrenocorticotrophic hormone. Impairment of visual acuity or visual field was presented in 33 patients at first diagnosis. Most patients (n = 64) received RT as postoperative adjuvant setting. Median RT dose was 45 Gy (range, 45 to 59.4 Gy). Median follow-up duration was 8 years (range, 3 to 22 years). In secreting tumors, hormone normalization rate was 55% (16 of 29 patients). For 25 patients with evaluable visual field and visual acuity test, 21 patients (84%) showed improvement of visual disturbance after treatment. The 10-year tumor control rate for non-secreting and secreting adenoma was 100% and 58%, respectively (p < 0.001). Progression free survival rate at 10 years was 98%. Only 1 patient experienced endocrinological recurrence. Following surgery, 60% (n = 44) suffered from pituitary function deficit. Late complication associated with RT was only 1 patient, who developed cataract. Surgery and RT are very effective and safe in hormonal and tumor growth control for secreting and non-secreting pituitary adenoma

  10. Long-term outcomes of surgery and radiotherapy for secreting and non-secreting pituitary adenoma

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Mi Young; Kim, Jin Hee; Oh, Young Kee; Kim, El [Dongsan Medical Center, Keimyung University School of Medicine, Daegu (Korea, Republic of)

    2016-06-15

    To investigate treatment outcome and long term complication after surgery and radiotherapy (RT) for pituitary adenoma. From 1990 to 2009, 73 patients with surgery and RT for pituitary adenoma were analyzed in this study. Median age was 51 years (range, 25 to 71 years). Median tumor size was 3 cm (range, 1 to 5 cm) with suprasellar (n = 21), cavernous sinus extension (n = 14) or both (n = 5). Hormone secreting tumor was diagnosed in 29 patients; 16 patients with prolactin, 12 patients with growth hormone, and 1 patient with adrenocorticotrophic hormone. Impairment of visual acuity or visual field was presented in 33 patients at first diagnosis. Most patients (n = 64) received RT as postoperative adjuvant setting. Median RT dose was 45 Gy (range, 45 to 59.4 Gy). Median follow-up duration was 8 years (range, 3 to 22 years). In secreting tumors, hormone normalization rate was 55% (16 of 29 patients). For 25 patients with evaluable visual field and visual acuity test, 21 patients (84%) showed improvement of visual disturbance after treatment. The 10-year tumor control rate for non-secreting and secreting adenoma was 100% and 58%, respectively (p < 0.001). Progression free survival rate at 10 years was 98%. Only 1 patient experienced endocrinological recurrence. Following surgery, 60% (n = 44) suffered from pituitary function deficit. Late complication associated with RT was only 1 patient, who developed cataract. Surgery and RT are very effective and safe in hormonal and tumor growth control for secreting and non-secreting pituitary adenoma.

  11. 76 FR 43684 - Verde Energy USA Trading, LLC; Supplemental Notice That Initial Market-Based Rate Filing Includes...

    Science.gov (United States)

    2011-07-21

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ER11-4041-000] Verde Energy USA Trading, LLC; Supplemental Notice That Initial Market-Based Rate Filing Includes Request for... Verde Energy USA Trading, LLC's application for market-based rate authority, with an accompanying rate...

  12. Similar incretin secretion in obese and non-obese Japanese subjects with type 2 diabetes

    DEFF Research Database (Denmark)

    Kozawa, Junji; Okita, Kohei; Imagawa, Akihisa

    2010-01-01

    Incretin secretion and effect on insulin secretion are not fully understood in patients with type 2 diabetes. We investigated incretin and insulin secretion after meal intake in obese and non-obese Japanese patients with type 2 diabetes compared to non-diabetic subjects. Nine patients with type 2......, incretin secretion does not differ between Japanese obese and non-obese patients with type 2 diabetes and non-diabetic subjects....... diabetes and 5 non-diabetic subjects were recruited for this study. Five diabetic patients were obese (BMI > or = 25) and 4 patients were non-obese (BMI

  13. 78 FR 29779 - Labor Affairs Council of the United States-Colombia Trade Promotion Agreement; Notice of Public...

    Science.gov (United States)

    2013-05-21

    ... Trade Promotion Agreement; Notice of Public Session Meeting AGENCY: International Labor Affairs Bureau... Labor Affairs Bureau (ILAB) of the U.S. Department of Labor gives notice of the public session of the meeting of the Labor Affairs Council (``Council'' or ``LAC''). The LAC public session has been rescheduled...

  14. Trade secrets protection mode of nuclear power plant

    International Nuclear Information System (INIS)

    Zeng Bin

    2015-01-01

    The paper analyzes the legal environment in which nuclear power enterprises are stayed, and mainly discusses the business secret protection modes of China's nuclear power enterprises. It is expected to provide a revelation and help for these enterprises to protect their business secrets. Firstly, the paper briefly expounds the legal basis of business secret protection and China's legalization status in this regard. Then it mainly puts forward the business secret management framework and postulations for nuclear power enterprises, and key points in application and protection of nuclear power business secret. (author)

  15. A local non-parametric model for trade sign inference

    Science.gov (United States)

    Blazejewski, Adam; Coggins, Richard

    2005-03-01

    We investigate a regularity in market order submission strategies for 12 stocks with large market capitalization on the Australian Stock Exchange. The regularity is evidenced by a predictable relationship between the trade sign (trade initiator), size of the trade, and the contents of the limit order book before the trade. We demonstrate this predictability by developing an empirical inference model to classify trades into buyer-initiated and seller-initiated. The model employs a local non-parametric method, k-nearest neighbor, which in the past was used successfully for chaotic time series prediction. The k-nearest neighbor with three predictor variables achieves an average out-of-sample classification accuracy of 71.40%, compared to 63.32% for the linear logistic regression with seven predictor variables. The result suggests that a non-linear approach may produce a more parsimonious trade sign inference model with a higher out-of-sample classification accuracy. Furthermore, for most of our stocks the observed regularity in market order submissions seems to have a memory of at least 30 trading days.

  16. 78 FR 30273 - Export Trade Certificate of Review

    Science.gov (United States)

    2013-05-22

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 84-24A12] Export Trade Certificate of Review ACTION: Notice of Application to Amend the Export Trade Certificate of Review Issued to... application to amend an Export Trade Certificate of Review (``Certificate''). This notice summarizes the...

  17. 78 FR 62585 - Export Trade Certificate of Review

    Science.gov (United States)

    2013-10-22

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 89-5A018] Export Trade Certificate of Review ACTION: Notice of Application to amend the Export Trade Certificate of Review Issued to... received an application to amend an Export Trade Certificate of Review (``Certificate''). This notice...

  18. 78 FR 36747 - Export Trade Certificate of Review

    Science.gov (United States)

    2013-06-19

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 89-4A018] Export Trade Certificate of Review ACTION: Notice of Application to amend the Export Trade Certificate of Review Issued to... received an application to amend an Export Trade Certificate of Review (``Certificate''). This notice...

  19. 78 FR 71643 - Certain Opaque Polymers; Notice of Commission Decision Amending the Complaint and Notice of...

    Science.gov (United States)

    2013-11-29

    ... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-883] Certain Opaque Polymers; Notice of Commission Decision Amending the Complaint and Notice of Investigation AGENCY: U.S. International Trade Commission. ACTION: Notice. SUMMARY: Notice is hereby given that the U.S. International Trade Commission has...

  20. 75 FR 80038 - Notice of Meetings of the Agricultural Policy Advisory Committee for Trade and the Agricultural...

    Science.gov (United States)

    2010-12-21

    ...Notice is hereby given that the Agricultural Policy Advisory Committee for Trade (APAC) and the Agricultural Technical Advisory Committees for Trade (ATAC) will hold closed meetings on January 13, 2011. The advisory committees are administered by USDA and the Office of the United States Trade Representative (USTR). The meetings are closed to the public in accordance with the Trade Act of 1974, 19 U.S.C. 2155(f)(2), and the Government in the Sunshine Act, 5 U.S.C. 552b(c)(4) and (6). USTR has determined that public access to this meeting would seriously compromise the development by the U.S. Government of trade policy priorities, negotiating objectives, or bargaining positions with respect to the operation of trade agreements and other matters arising in connection with the development, implementation, and administration of the trade policy of the United States. Topics will include Doha Round negotiations in the World Trade Organization (WTO), WTO accession negotiations, and negotiations in bilateral and regional free trade agreements.

  1. 76 FR 71378 - Labor Advisory Committee for Trade Negotiations and Trade Policy

    Science.gov (United States)

    2011-11-17

    ... DEPARTMENT OF LABOR Office of the Secretary Labor Advisory Committee for Trade Negotiations and Trade Policy ACTION: Meeting notice. SUMMARY: Pursuant to the provisions of the Federal Advisory... Committee for Trade Negotiation and Trade Policy. Date, Time, Place: November 30, 2011; 2-4:30 p.m.; U.S...

  2. 77 FR 65581 - Labor Advisory Committee for Trade Negotiations and Trade Policy

    Science.gov (United States)

    2012-10-29

    ... DEPARTMENT OF LABOR Office of the Secretary Labor Advisory Committee for Trade Negotiations and Trade Policy ACTION: Meeting notice. SUMMARY: Pursuant to the provisions of the Federal Advisory... Committee for Trade Negotiation and Trade Policy. Date, Time, Place: November 13, 2012; 10:00 a.m.-12:00 p.m...

  3. 77 FR 31393 - Labor Advisory Committee for Trade Negotiations and Trade Policy

    Science.gov (United States)

    2012-05-25

    ... DEPARTMENT OF LABOR Office of the Secretary Labor Advisory Committee for Trade Negotiations and Trade Policy ACTION: Notice of renewal. SUMMARY: Pursuant to the Federal Advisory Committee Act (FACA), as amended (5 U.S.C. App. 2), the Secretary of Labor and the United States Trade Representative have...

  4. 78 FR 55056 - Notice of Petitions by Firms for Determination of Eligibility To Apply for Trade Adjustment...

    Science.gov (United States)

    2013-09-09

    ... vehicles such as military transport and civilian first responder utility vehicles. Nedza International Inc... DEPARTMENT OF COMMERCE Economic Development Administration Notice of Petitions by Firms for Determination of Eligibility To Apply for Trade Adjustment Assistance AGENCY: Economic Development...

  5. 77 FR 12007 - Notice of Petitions by Firms tor Determination of Eligibility to Apply For Trade Adjustment...

    Science.gov (United States)

    2012-02-28

    ... DEPARTMENT OF COMMERCE Economic Development Administration Notice of Petitions by Firms tor Determination of Eligibility to Apply For Trade Adjustment Assistance AGENCY: Economic Development... Kearse, Eligibility Certifier. [FR Doc. 2012-4626 Filed 2-27-12; 8:45 am] BILLING CODE 3510-WH-P ...

  6. 77 FR 20054 - Bureau of International Labor Affairs; Labor Advisory Committee for Trade Negotiations and Trade...

    Science.gov (United States)

    2012-04-03

    ... DEPARTMENT OF LABOR Office of the Secretary Bureau of International Labor Affairs; Labor Advisory Committee for Trade Negotiations and Trade Policy ACTION: Meeting Notice. SUMMARY: Pursuant to the... meeting of the Labor Advisory Committee for Trade Negotiation and Trade Policy. Date, Time, Place: May 14...

  7. 76 FR 31641 - Bureau of International Labor Affairs; Labor Advisory Committee for Trade Negotiations and Trade...

    Science.gov (United States)

    2011-06-01

    ... DEPARTMENT OF LABOR Office of the Secretary Bureau of International Labor Affairs; Labor Advisory Committee for Trade Negotiations and Trade Policy ACTION: Meeting notice. SUMMARY: Pursuant to the... meeting of the Labor Advisory Committee for Trade Negotiation and Trade Policy. Date, Time, Place: June 28...

  8. 75 FR 78758 - Bureau of International Labor Affairs; Labor Advisory Committee for Trade Negotiations and Trade...

    Science.gov (United States)

    2010-12-16

    ... DEPARTMENT OF LABOR Office of the Secretary Bureau of International Labor Affairs; Labor Advisory Committee for Trade Negotiations and Trade Policy ACTION: Meeting notice. SUMMARY: Pursuant to the... meeting of the Labor Advisory Committee for Trade Negotiation and Trade Policy. Date, Time, Place: January...

  9. 76 FR 66937 - Privacy Act of 1974; Department of Homeland Security/United States Secret Service-003 Non...

    Science.gov (United States)

    2011-10-28

    ... 1974; Department of Homeland Security/United States Secret Service--003 Non-Criminal Investigation... Security/United States Secret Service--003 Non-Criminal Investigation Information System.'' As a result of... Secret Service, 245 Murray Lane SW., Building T-5, Washington, DC 20223. For privacy issues please...

  10. Suitability of non-energy GHGs for emissions trading

    International Nuclear Information System (INIS)

    Haites, E.; Proestos, A.

    2000-01-01

    This paper assesses the suitability of different sources of non-energy greenhouse gases for emissions trading. Different forms of emissions trading are defined and criteria for determining whether a source is suitable for emissions trading are proposed. The suitability for emissions trading is assessed for: methane (CH4) from oil and gas production; CH4 from coal mines; CH4 from landfills; CH4 from wastewater treatment; CH4 from enteric fermentation; CH4 from livestock manure, nitrous oxide (N2O) from adipic acid production; N2O from fertilizer use; N2O from nitric acid production, carbon dioxide (CO2) and perfluorocarbons (PFCs) from aluminum smelting; sulphur hexafluoride (SF6) from magnesium smelting and die casting; HFCs from HCFC production, other uses of SF6, PFCs and hydrofluorocarbons (HFCs); CO2 from ammonia production; lime and cement production, and iron ore reduction

  11. Non-coherent capacity of secret-key agreement with public discussion

    KAUST Repository

    Agrawal, Anurag

    2011-06-01

    We study the Rayleigh fading non-coherent capacity of secret-key agreement with public discussion, where neither the sender nor the receivers have access to instantaneous channel state information (CSI) of any channel. We present two results. At high Signal-to-Noise Ratio (SNR), the secret-key capacity is bounded in SNR, regardless of the number of antennas at each terminal. Second, for a system with a single antenna at both the legitimate and the eavesdropper terminals and an arbitrary number of transmit antennas, the secret-key capacity-achieving input distribution is discrete, with a finite number of mass points. Numerically we observe that at low-SNR, the capacity achieving distribution has two mass points with one of them at the origin. © 2011 IEEE.

  12. Non-coherent capacity of secret-key agreement with public discussion

    KAUST Repository

    Agrawal, Anurag; Rezki, Zouheir; Khisti, Ashish J.; Alouini, Mohamed-Slim

    2011-01-01

    We study the Rayleigh fading non-coherent capacity of secret-key agreement with public discussion, where neither the sender nor the receivers have access to instantaneous channel state information (CSI) of any channel. We present two results. At high Signal-to-Noise Ratio (SNR), the secret-key capacity is bounded in SNR, regardless of the number of antennas at each terminal. Second, for a system with a single antenna at both the legitimate and the eavesdropper terminals and an arbitrary number of transmit antennas, the secret-key capacity-achieving input distribution is discrete, with a finite number of mass points. Numerically we observe that at low-SNR, the capacity achieving distribution has two mass points with one of them at the origin. © 2011 IEEE.

  13. EPCRA Trade Secret Forms and Instructions

    Science.gov (United States)

    This form is required in order to substantiate claims of trade secrecy. You must be able to describe safeguarding measures and disclosure history for the specific chemical identity, and identify harm to your competitive position.

  14. 78 FR 16692 - Chemical Facility Anti-Terrorism Standards (CFATS)

    Science.gov (United States)

    2013-03-18

    ... trade secrets, confidential commercial or financial information, Chemical-terrorism Vulnerability... from other comments in response to this notice. Comments containing trade secrets, confidential... Burden Cost (operating/maintaining): $3,977. Instrument: Notification of a New Top Screen. Frequency: On...

  15. 78 FR 3044 - Exchange Traded Spreads Trust, et al.; Notice of Application

    Science.gov (United States)

    2013-01-15

    ... the series to deposit securities into, and receive securities from, the series in connection with the... securities (``Equity Funds'') or fixed income securities (``Fixed Income Funds'') traded in the U.S. or non-U... Equity Funds''), Fixed Income Funds that invest in fixed income securities traded in the U.S. market...

  16. 78 FR 59004 - Export Trade Certificate of Review

    Science.gov (United States)

    2013-09-25

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 13-00001] Export Trade Certificate of Review ACTION: Notice of Application for an Export Trade Certificate of Review to Emporia Trading LLC, Application No. 13-00001. SUMMARY: The Export Trading Company Affairs (``ETCA'') unit, Office...

  17. Simulation analysis of emissions trading impact on a non-utility power plant

    International Nuclear Information System (INIS)

    Imran, Kashif; Ahmad, Intesar; Hassan, Tehzeebul; Aslam, Muhammad Farooq; Ngan, Hon-Wing

    2009-01-01

    Non-utility power plants can competitively participate in open electricity market to reduce operational costs but in the absence of pollution charges or emissions trading such generators are tempted to cause greater pollution for profit maximization. This paper presents a solution that incorporates pollution charges for nitrogen oxides and sulphur dioxide emissions in line with existing national environmental quality standards and a new carbon dioxide emissions trading mechanism. A novel approach has been used for allocation of allowable emissions that favors efficiently fuelled and environmentally friendly operation for maximizing profit. Impact of proposed carbon trading on economical utilization of enormous indigenous coal reserves has been analyzed and determined to be acceptable. Software developed in this paper, harnessing Sequential Quadratic Programming capabilities of Matlab, is shown to be adequate simulation tool for various emissions trading schemes and an useful operational decision making tool for constrained non-linear optimization problem of a non-utility power plant. (author)

  18. Simulation analysis of emissions trading impact on a non-utility power plant

    Energy Technology Data Exchange (ETDEWEB)

    Imran, Kashif; Ahmad, Intesar [Department of Electrical Engineering, COMSATS Institute of IT, Lahore (Pakistan); Hassan, Tehzeebul [Department of Electrical Engineering, University of Engineering and Technology (UET), Lahore (Pakistan); Aslam, Muhammad Farooq [Department of Electrical Engineering, University of Management and Technology (UMT), Lahore (Pakistan); Ngan, Hon-Wing [Department of Electrical Engineering, Hong Kong Polytechnic University (China)

    2009-12-15

    Non-utility power plants can competitively participate in open electricity market to reduce operational costs but in the absence of pollution charges or emissions trading such generators are tempted to cause greater pollution for profit maximization. This paper presents a solution that incorporates pollution charges for nitrogen oxides and sulphur dioxide emissions in line with existing national environmental quality standards and a new carbon dioxide emissions trading mechanism. A novel approach has been used for allocation of allowable emissions that favors efficiently fuelled and environmentally friendly operation for maximizing profit. Impact of proposed carbon trading on economical utilization of enormous indigenous coal reserves has been analyzed and determined to be acceptable. Software developed in this paper, harnessing Sequential Quadratic Programming capabilities of Matlab, is shown to be adequate simulation tool for various emissions trading schemes and an useful operational decision making tool for constrained non-linear optimization problem of a non-utility power plant. (author)

  19. 78 FR 78818 - Export Trade Certificate of Review

    Science.gov (United States)

    2013-12-27

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 13-00001] Export Trade Certificate of Review ACTION: Notice of Issuance of an Export Trade Certificate of Review to Emporia Trading LLC, Application No. 13-00001. SUMMARY: The U.S. Department of Commerce issued an Export Trade...

  20. 75 FR 8040 - Export Trade Certificate of Review

    Science.gov (United States)

    2010-02-23

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application 10-00001] Export Trade Certificate of Review ACTION: Notice of Application for an Export Trade Certificate of Review from Alaska Longline Cod Commission (``ALCC'') SUMMARY: The Export Trading Company Affairs (``ETCA'') unit, Office of...

  1. 77 FR 2036 - Export Trade Certificate of Review

    Science.gov (United States)

    2012-01-13

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 92-10A001] Export Trade Certificate of Review ACTION: Notice of issuance of an Export Trade Certificate of Review to Aerospace... an amended Export Trade Certificate of Review to Aerospace Industries of America on September 27...

  2. 78 FR 72865 - Export Trade Certificate of Review

    Science.gov (United States)

    2013-12-04

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 92-12A001] Export Trade Certificate of Review ACTION: Notice of application to amend the Export Trade Certificate of Review issued to..., has received an application to amend an Export Trade Certificate of Review (``Certificate''). This...

  3. 78 FR 36745 - Export Trade Certificate of Review

    Science.gov (United States)

    2013-06-19

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 87-9A001] Export Trade Certificate of Review ACTION: Notice of Application to amend the Export Trade Certificate of Review Issued to..., has received an application to amend an Export Trade Certificate of Review (``Certificate''). This...

  4. 78 FR 78816 - Export Trade Certificate of Review

    Science.gov (United States)

    2013-12-27

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 87-9A001] Export Trade Certificate of Review ACTION: Notice of Issuance of an Amended Export Trade Certificate of Review to... issued an amended Export Trade Certificate of Review to Independent Film and Television Alliance (``IFTA...

  5. Analysis of the “Human Factor” as an Information Threat to Trade Secrets and Counteractions – Spying is in!

    OpenAIRE

    Marjanova Jovanov, Tamara

    2010-01-01

    “Economic espionage and trade secret theft threaten our nation’s national security and economic well being.” Since the 1970s brought the explosion of the Information Revolution and the rise of personal computers, we’ve become even more interested in the brain and how it works. We shouldn’t be aware of Artificial Intelligence and the smart machines of the 21st Century, but of the people in our surroundings and their ability to be corrupted from our competitors. How can we know who is rea...

  6. 76 FR 66775 - Defense Trade Advisory Group; Notice of Open Meeting

    Science.gov (United States)

    2011-10-27

    ... further study. Agenda topics will be posted on the Directorate of Defense Trade Controls' Web site, at... requesting reasonable accommodation should notify the Alternate DFO by the same date. Each non-member...

  7. Secretion of non-cell-bound phytase by the yeast Pichia kudriavzevii TY13.

    Science.gov (United States)

    Hellström, A; Qvirist, L; Svanberg, U; Veide Vilg, J; Andlid, T

    2015-05-01

    Mineral deficiencies cause several health problems in the world, especially for populations consuming cereal-based diets rich in the anti-nutrient phytate. Our aim was to characterize the phytate-degrading capacity of the yeast Pichia kudriavzevii TY13 and its secretion of phytase. The phytase activity in cell-free supernatants from cultures with 100% intact cells was 35-190 mU ml(-1) depending on the media. The Km was 0.28 mmol l(-1) and the specific phytase activity 0.32 U mg(-1) total protein. The phytase activity and secretion of extracellular non-cell-bound phytase was affected by the medium phosphate concentrations. Further, addition of yeast extract had a clearly inducing effect, resulting in over 60% of the cultures total phytase activity as non-cell-bound. Our study reveals that it is possible to achieve high extracellular phytase activity from the yeast P. kudriavzevii TY13 by proper composition of the growth medium. TY13 could be a promising future starter culture for fermented foods with improved mineral bioavailability. Using strains that secrete phytase to the food matrix may significantly improve the phytate degradation by facilitating the enzyme-to-substrate interaction. The secreted non-cell-bound phytase activities by TY13 could further be advantageous in industrial production of phytase. © 2015 The Society for Applied Microbiology.

  8. 78 FR 57620 - Trade Mission to Philippines and Malaysia

    Science.gov (United States)

    2013-09-19

    ... DEPARTMENT OF COMMERCE International Trade Administration Trade Mission to Philippines and Malaysia AGENCY: International Trade Administration, Department of Commerce. ACTION: Notice. SUMMARY: The... trade mission to Manila, Philippines and Kuala Lumpur, Malaysia scheduled for October 23-October 30...

  9. 78 FR 13861 - Export Trade Certificate of Review

    Science.gov (United States)

    2013-03-01

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 85-17A18] Export Trade Certificate of Review ACTION: Notice of Issuance of an Amended Export Trade Certificate of Review to U.S..., Office of Competition and Economic Analysis (OCEA), has issued an amended Export Trade Certificate of...

  10. 77 FR 61744 - Export Trade Certificate of Review

    Science.gov (United States)

    2012-10-11

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 10-3A001] Export Trade Certificate of Review ACTION: Notice of Issuance of an Export Trade Certificate of Review to Alaska Longline... Commerce issued an amended Export Trade Certificate of Review to the Alaska Longline Cod Commission (``ALCC...

  11. 77 FR 12562 - Export Trade Certificate of Review

    Science.gov (United States)

    2012-03-01

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 10-2A001] Export Trade Certificate of Review ACTION: Notice of Application (10-2A001) to Amend the Export Trade Certificate of Review..., has received an application to amend an Export Trade Certificate of Review (``Certificate''). This...

  12. 78 FR 25060 - Export Trade Certificate of Review

    Science.gov (United States)

    2013-04-29

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 92-11A001] Export Trade Certificate of Review ACTION: Notice of Issuance of an amended Export Trade Certificate of Review to Aerospace... issued an amended Export Trade Certificate of Review to Aerospace Industries Association of America on...

  13. 78 FR 5778 - Export Trade Certificate of Review

    Science.gov (United States)

    2013-01-28

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 92-11A01] Export Trade Certificate of Review ACTION: Notice of Application (92-11A01) to amend the Export Trade Certificate of Review... of Commerce, has received an application to amend an Export Trade Certificate of Review...

  14. 77 FR 72324 - Export Trade Certificate of Review

    Science.gov (United States)

    2012-12-05

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 85-17A18] Export Trade Certificate of Review ACTION: Notice of Application to Amend the Export Trade Certificate of Review Issued to... to amend an Export [[Page 72325

  15. Open Source and Trade Data for Non-Proliferation: Challenges and Opportunities

    International Nuclear Information System (INIS)

    Stewart, I.; Gillard, N.

    2015-01-01

    This paper explores what more systematic exploitation of trade data can contribute to the state evaluation process. The paper begins by setting out a typology of trade data, which groups the data into five categories: · Government Declared Data, which is prepared and submitted by States to an international authority for non-proliferation purposes. · Government Recorded Data, which includes information collected by the state for its own purposes, and which is not routinely submitted to international authorities for non-proliferation purposes. It includes (some) export licencing data, customs data, and business registration information. · Business-held data, which includes information on a company's own products and customers, but also ''market intelligence''. · Intelligence and Enforcement Derived Information, which can include information on specific procurement attempts, networks, or procurement requirements. · Procurement Requirements Information, which can include information released by a programme for the purpose of seeking goods or services. Challenges and opportunities related to further exploitation of trade data sources in each category are then explored, as are factors related to accessibility (both in terms of mandates and more practical considerations), reliability (including presentation of a typology), completeness, and duplication in data. Next, the paper explores how the IAEA can systematically collect, integrate and analyze the various sources of trade data given the considerations outlined above. In particular, this section focuses on how data in variable structures can be integrated into the state evaluation process. In concluding, the paper will describe how the newly formed ''Collaboration on Open Source and Trade Analysis for Non-proliferation'' (COSTA-NP) is seeking to develop each of the categories of trade data. The paper links to research objectives 1.3, 1.4, 2.1, 2.3, and 2.4 of the IAEA

  16. 76 FR 1101 - Property Traded on an Established Market

    Science.gov (United States)

    2011-01-07

    ... Property Traded on an Established Market AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Notice... regulations relating to determining when property is traded on an established market (that is, publicly traded... traded on an established securities market (often referred to as ``publicly traded''), the issue price of...

  17. 75 FR 57544 - Defense Trade Advisory Group; Notice of Open Meeting

    Science.gov (United States)

    2010-09-21

    ... Trade Controls' Web site, at http://www.pmddtc.state.gov 2 weeks prior to the meeting. Members of the... requesting reasonable accommodation should notify the Alternate DFO by the same date. Each non-member...

  18. 77 FR 28853 - Export Trade Certificate of Review

    Science.gov (United States)

    2012-05-16

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 10-2A001] Export Trade Certificate of Review ACTION: Notice of issuance of an Export Trade Certificate of Review to Alaska Longline... Export Trade Certificate of Review Alaska Longline Cod Commission (``ALCC'') on May 7, 2012. This is the...

  19. Chemical composition of metapleural gland secretions of fungus-growing and non-fungus-growing ants.

    Science.gov (United States)

    Vieira, Alexsandro S; Morgan, E David; Drijfhout, Falko P; Camargo-Mathias, Maria I

    2012-10-01

    The metapleural gland is exclusive to ants, and unusual among exocrine glands in having no mechanism for closure and retention of secretion. As yet, no clear conclusion has been reached as to the function of metapleural gland secretion. Metapleural gland secretions were investigated for fungus-growing ants representing the derived attines Trachymyrmex fuscus, Atta laevigata, and Acromyrmex coronatus, the basal attines Apterostigma pilosum and Mycetarotes parallelus, and non-fungus-growing ants of the tribes Ectatommini (Ectatomma brunneum) and Myrmicini (Pogonomyrmex naegeli). Our results showed that the secretions of leaf-cutting ants (A. laevigata and A. coronatus) and the derived attine, T. fuscus, contain a greater variety and larger quantities of volatile compounds than those of myrmicine and ectatommine ants. The most abundant compounds found in the metapleural glands of A. laevigata and A. coronatus were hydroxyacids, and phenylacetic acid (only in A. laevigata). Indole was present in all groups examined, while skatole was found in large quantities only in attines. Ketones and aldehydes are present in the secretion of some attines. Esters are present in the metapleural gland secretion of all species examined, although mainly in A. laevigata, A. coronatus, and T. fuscus. Compared with basal attines and non-fungus-growing ants, the metapleural glands of leaf-cutting ants produce more acidic compounds that may have an antibiotic or antifungal function.

  20. 75 FR 31505 - Defense Trade Advisory Group; Notice of Open Meeting

    Science.gov (United States)

    2010-06-03

    ... topics for further study. Agenda topics will be posted on the Directorate of Defense Trade Controls' Web... accommodation should notify the Alternate DFO by the same date. Each non-member observer or DTAG member that...

  1. 75 FR 70973 - Registration of Foreign Boards of Trade

    Science.gov (United States)

    2010-11-19

    ... prospectively to facilitate direct access to the electronic trading system of a foreign board of trade by its U... Trade; Proposed Rule #0;#0;Federal Register / Vol. 75 , No. 223 / Friday, November 19, 2010 / Proposed... Registration of Foreign Boards of Trade AGENCY: Commodity Futures Trading Commission. ACTION: Notice of...

  2. 75 FR 51451 - Combined Notice of Filings # 1

    Science.gov (United States)

    2010-08-20

    ... & Trading, LP; GP Big Island, LLC; Brunswick Cellulose, Inc.; Georgia-Pacific Cedar Springs LLC; Georgia...-Pacific Toledo LLC; Leaf River Cellulose, LLC. Description: Notice of Non-material Change in Status... submission of protests and interventions in lieu of paper, using the FERC Online links at http://www.ferc.gov...

  3. Mucous solids and liquid secretion by airways: studies with normal pig, cystic fibrosis human, and non-cystic fibrosis human bronchi

    Science.gov (United States)

    Martens, Chelsea J.; Inglis, Sarah K.; Valentine, Vincent G.; Garrison, Jennifer; Conner, Gregory E.

    2011-01-01

    To better understand how airways produce thick airway mucus, nonvolatile solids were measured in liquid secreted by bronchi from normal pig, cystic fibrosis (CF) human, and non-CF human lungs. Bronchi were exposed to various secretagogues and anion secretion inhibitors to induce a range of liquid volume secretion rates. In all three groups, the relationship of solids concentration (percent nonvolatile solids) to liquid volume secretion rate was curvilinear, with higher solids concentration associated with lower rates of liquid volume secretion. In contrast, the secretion rates of solids mass and water mass as functions of liquid volume secretion rates exhibited positive linear correlations. The y-intercepts of the solids mass-liquid volume secretion relationships for all three groups were positive, thus accounting for the higher solids concentrations in airway liquid at low rates of secretion. Predictive models derived from the solids mass and water mass linear equations fit the experimental percent solids data for the three groups. The ratio of solids mass secretion to liquid volume secretion was 5.2 and 2.4 times higher for CF bronchi than for pig and non-CF bronchi, respectively. These results indicate that normal pig, non-CF human, and CF human bronchi produce a high-percent-solids mucus (>8%) at low rates of liquid volume secretion (≤1.0 μl·cm−2·h−1). However, CF bronchi produce mucus with twice the percent solids (∼8%) of pig or non-CF human bronchi at liquid volume secretion rates ≥4.0 μl·cm−2·h−1. PMID:21622844

  4. 78 FR 53727 - Export Trade Certificate of Review

    Science.gov (United States)

    2013-08-30

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 84-24A12] Export Trade Certificate of Review ACTION: Notice of Issuance of an Export Trade Certificate of Review to Northwest Fruit Exporters, Application No. 84-24A12. SUMMARY: The U.S. Department of Commerce issued an amended Export Trade...

  5. 78 FR 1837 - Export Trade Certificate of Review

    Science.gov (United States)

    2013-01-09

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 84-23A12] Export Trade Certificate of Review ACTION: Notice of issuance of an Export Trade Certificate of Review to Northwest Fruit Exporters, Application No. 84-23A12. SUMMARY: The U.S. Department of Commerce issued an amended Export Trade...

  6. Uteroglobin, an apically secreted protein of the uterine epithelium, is secreted non-polarized form MDCK cells and mainly basolaterally from Caco-2 cells

    DEFF Research Database (Denmark)

    Vogel, L K; Suske, G; Beato, M

    1993-01-01

    A complete cDNA encoding rabbit uteroglobin was constructed and expressed in MDCK and Caco-2 cells. The MDCK cells secrete uteroglobin in approximately equal amounts to the apical and the basolateral side, whereas the Caco-2 cells secrete uteroglobin mainly to the basolateral side. Both MDCK...... and Caco-2 cells thus secrete uteroglobin in a non-sorted manner. It has, however, previously been shown that uteroglobin is secreted exclusively at the apical membrane in primary cell culture of endometrial epithelial cells [S.K. Mani et al. (1991) Endocrinology 128, 1563-1573]. This suggests that either...... the endometrial epithelium has an apical default pathway or recognises a sorting signal not recognised by MDCK cells and Caco-2 cells. Our data thus show that a soluble molecule can be secreted at the apical, the basolateral or both membranes depending on the cell type....

  7. Is trade openness good for environment in South Korea? The role of non-fossil electricity consumption.

    Science.gov (United States)

    Zhang, Shun

    2018-04-01

    The paper investigates the linkage of carbon dioxide (CO 2 ) emissions, per capita real output, share of non-fossil electricity consumption, and trade openness in South Korea from 1971 to 2013. The empirical results indicate that the environmental Kuznets curve (EKC) is supported by autoregressive distributed lag (ARDL) test. Both short- and long-run estimates indicate that increasing non-fossil electricity consumption can mitigate environmental degradation, and increasing trade aggravates carbon dioxide emissions. By Granger causality, long-run causalities are found in both equations of CO 2 emissions and trade openness, as well as exports and imports. In the short-run, evidence indicates feedback linkage between output and trade, unidirectional linkages from trade to emissions, from emissions to output, and from output to non-fossil electricity use. Therefore, South Korea should strengthen the sustainable economy, consume clean energy, and develop green trade.

  8. 75 FR 65449 - Export Trade Certificate of Review

    Science.gov (United States)

    2010-10-25

    ... of Competition and Economic Analysis, International Trade Administration, by telephone at (202) 482... CFR part 325 (2010). The Office of Competition and Economic Analysis (``OCEA'') is issuing this notice... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 94-4A007] Export Trade...

  9. 77 FR 58809 - Export Trade Certificate of Review

    Science.gov (United States)

    2012-09-24

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 12-00005] Export Trade Certificate of Review ACTION: Notice of issuance of an Export Trade Certificate of Review to Colombia Rice Export Quota, Inc. (``COL-RICE'') (Application 12-00005). SUMMARY: On August 28, 2012, the U.S...

  10. 77 FR 53865 - Export Trade Certificate of Review

    Science.gov (United States)

    2012-09-04

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 12-00004] Export Trade Certificate of Review ACTION: Notice of issuance of an Export Trade Certificate of Review to Colombia Poultry Export Quota, Inc. (``COLOM-PEQ)'') (Application 12-00004). SUMMARY: On August 14, 2012, the U.S...

  11. 76 FR 70491 - Exemptions From Certain Prohibited Transaction Restrictions

    Science.gov (United States)

    2011-11-14

    ...) shall be authorized to examine trade secrets of Applicant, or commercial or financial information which... paragraph (d)(1)(B)- (D) shall be authorized to examine trade secrets of FRC, RTC or their affiliates, or... in the Notice, which is located at the conclusion of Representation 15 near the top of page 34266 of...

  12. 77 FR 41970 - Export Trade Certificate of Review

    Science.gov (United States)

    2012-07-17

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 12-00001] Export Trade Certificate of Review ACTION: Notice of issuance of an Export Trade Certificate of Review to Panama Poultry Export Quota, Inc. (``PAN-PEQ'') (Application 12-00001). SUMMARY: On June 25, 2012, the U.S. Department...

  13. 78 FR 31517 - Export Trade Certificate of Review

    Science.gov (United States)

    2013-05-24

    ... DEPARTMENT OF COMMERCE International Trade Administration [Application No. 99-5A002] Export Trade Certificate of Review ACTION: Notice of Issuance of an amended Export Trade Certificate of Review to California Almond Export Association, LLC (``CAEA'') (Application 99-5A002). SUMMARY: The U.S. Department of...

  14. Price volatility, trading volume, and market depth in Asian commodity futures exchanges

    Directory of Open Access Journals (Sweden)

    Tanachote Boonvorachote

    2016-01-01

    Full Text Available This paper empirically investigates the impact of trading activity including trading volume and open interest on price volatility in Asian futures exchanges. Trading volume and open interest represent market information for investors. This study uses three different definitions of volatility: (1 daily volatility measured by close-to-close returns, (2 non-trading volatility measured by close-to-open returns, and (3 trading volatility measured by open-to-close returns. The impact of trading volume and open interest on price volatility is investigated. Following Bessembinder and Seguin (1993, volume and open interest are divided into expected and unexpected components. The GARCH (1,1 model is employed using expected and unexpected components of trading activity (volume and open interest as explanatory variables. The results show a positive contemporaneous relationship between expected and unexpected trading volume and volatility, while open interest mitigates volatility. Policy makers can use these findings to suggest to investors that trading activity (volume and open interest is a proxy of market information flowing to exchanges, especially unexpected trading activity. New information flowing to exchanges can mostly be noticed in unexpected trading volumes and open interests.

  15. Gravity Models of Trade-Based Money Laundering

    NARCIS (Netherlands)

    Ferwerda, Joras|info:eu-repo/dai/nl/314405526; Kattenberg, Marc|info:eu-repo/dai/nl/357208986; Chang, Han-Hsin|info:eu-repo/dai/nl/357209370; Unger, Brigitte|info:eu-repo/dai/nl/290994926; Groot, Loek|info:eu-repo/dai/nl/073642398; Bikker, Jaap|info:eu-repo/dai/nl/06912261X

    Several attempts have been made in the economics literature to measure money laundering. However, the adequacy of these models is difficult to assess, as money laundering takes place secretly and, hence, goes unobserved. An exception is trade-based money laundering (TBML), a special form of trade

  16. 78 FR 59005 - Civil Nuclear Trade Advisory Committee Meeting

    Science.gov (United States)

    2013-09-25

    ... ability to participate in the international market. Topics to be considered: The agenda for the October 16... DEPARTMENT OF COMMERCE International Trade Administration Civil Nuclear Trade Advisory Committee Meeting AGENCY: International Trade Administration (ITA), Commerce (DOC). ACTION: Notice of federal...

  17. Impacts of Tariff and Non-tariff Trade Barriers on Global Forest Products Trade: An Application of the Global Forest Products Model

    NARCIS (Netherlands)

    Sun, L.; Bogdanski, B.; Stennes, B.; Kooten, van G.C.

    2010-01-01

    Although there has been considerable analysis on the effects of trade measures on forest product markets, these have tended to focus on tariffs. There is growing concern about the impact of non-tariff trade measures on the global forest product sector. The objective of this study is to fill a gap

  18. Glucose-induced glucagon-like Peptide 1 secretion is deficient in patients with non-alcoholic fatty liver disease.

    Directory of Open Access Journals (Sweden)

    Christine Bernsmeier

    Full Text Available The incretins glucagon-like peptide-1 (GLP-1 and glucose-dependent insulinotropic polypeptide (GIP are gastrointestinal peptide hormones regulating postprandial insulin release from pancreatic β-cells. GLP-1 agonism is a treatment strategy in Type 2 diabetes and is evaluated in Non-alcoholic fatty liver disease (NAFLD. However, the role of incretins in its pathophysiology is insufficiently understood. Studies in mice suggest improvement of hepatic steatosis by GLP-1 agonism. We determined the secretion of incretins after oral glucose administration in non-diabetic NAFLD patients.N=52 patients (n=16 NAFLD and n=36 Non-alcoholic steatohepatitis (NASH patients and n=50 matched healthy controls were included. Standardized oral glucose tolerance test was performed. Glucose, insulin, glucagon, GLP-1 and GIP plasma levels were measured sequentially for 120 minutes after glucose administration.Glucose induced GLP-1 secretion was significantly decreased in patients compared to controls (p<0.001. In contrast, GIP secretion was unchanged. There was no difference in GLP-1 and GIP secretion between NAFLD and NASH subgroups. All patients were insulin resistant, however HOMA2-IR was highest in the NASH subgroup. Fasting and glucose-induced insulin secretion was higher in NAFLD and NASH compared to controls, while the glucose lowering effect was diminished. Concomitantly, fasting glucagon secretion was significantly elevated in NAFLD and NASH.Glucose-induced GLP-1 secretion is deficient in patients with NAFLD and NASH. GIP secretion is contrarily preserved. Insulin resistance, with hyperinsulinemia and hyperglucagonemia, is present in all patients, and is more severe in NASH compared to NAFLD. These pathophysiologic findings endorse the current evaluation of GLP-1 agonism for the treatment of NAFLD.

  19. Non-financial Results of Performance Indicators of Trade and Industry Chambers in Ukraine

    Directory of Open Access Journals (Sweden)

    Bogdana V. Aleksandrova

    2014-03-01

    Full Text Available The article deals with non-financial results review of Trade and Industry Chamber, the assessment of competitiveness in the Ukrainian market. To achieve the desired goal we should do the following: 1.\tIdentify categories of research 2.\tSystemize available statistics. 3.\tTo evaluate dynamics of main categories 4.\tConduct an assessment of non-financial indicators of Trade and Industry Chamber 5.\tIdentify the level of competitiveness of Trade and Industry Chamber of Ukraine on domestic market. Methods used by author to address these issues: index-linked, method of correlation analysis, method of expert assessment. As a result of the study, non-financial indicators of organization’s activities have been analyzed, the dynamics of membership base and the scope of delivered services have been identified as well as the level of organization’s competitiveness. The most promising services have been highlighted.

  20. 75 FR 70215 - Environmental Technologies Trade Advisory Committee (ETTAC), Request for Nominations

    Science.gov (United States)

    2010-11-17

    ... DEPARTMENT OF COMMERCE International Trade Administration Environmental Technologies Trade...: Notice of solicitation of nominations for membership on the Environmental Technologies Trade Advisory Committee (ETTAC). SUMMARY: The Environmental Technologies Trade Advisory Committee (ETTAC) was established...

  1. 75 FR 23227 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-05-03

    ... DEPARTMENT OF AGRICULTURE Foreign Agricultural Service Trade Adjustment Assistance for Farmers AGENCY: Foreign Agricultural Service, USDA. ACTION: Notice. The Administrator, Foreign Agricultural... be obtained at the Web site for the Trade Adjustment Assistance for Farmers program. The URL is http...

  2. 75 FR 23226 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-05-03

    ... DEPARTMENT OF AGRICULTURE Foreign Agricultural Service Trade Adjustment Assistance for Farmers AGENCY: Foreign Agricultural Service, USDA. ACTION: Notice. The Administrator, Foreign Agricultural... Web site for the Trade Adjustment Assistance for Farmers program. The URL is http://www.fas.usda.gov...

  3. 16 CFR 680.23 - Contents of opt-out notice; consolidated and equivalent notices.

    Science.gov (United States)

    2010-01-01

    ... equivalent notices. 680.23 Section 680.23 Commercial Practices FEDERAL TRADE COMMISSION THE FAIR CREDIT REPORTING ACT AFFILIATE MARKETING § 680.23 Contents of opt-out notice; consolidated and equivalent notices... receiving marketing than is required by this part, the requirements of this section may be satisfied by...

  4. 78 FR 6810 - U.S. Infrastructure Trade Mission to Colombia and Panama-Amendment

    Science.gov (United States)

    2013-01-31

    ... Foreign Commercial Service (CS) is publishing this supplement to the Notice of the U.S. Infrastructure... December, 2012. Due to the December holiday season, it has been determined that an additional time is... releases to general and trade media, direct mail, broadcast fax, notices by industry trade associations and...

  5. 78 FR 16470 - U.S. Infrastructure Trade Mission to Colombia and Panama-Amendment

    Science.gov (United States)

    2013-03-15

    ... Foreign Commercial Service (CS) is publishing this supplement to the Notice of the U.S. Healthcare Trade.... Due to the recent snow closures and upcoming Easter holiday season, it has been determined that an..., notices by industry trade associations and other multiplier groups, and publicity at industry meetings...

  6. 76 FR 2720 - Trade Adjustment Assistance Program; Designation of Certifying Officers

    Science.gov (United States)

    2011-01-14

    ... their employment by certain types of foreign trade. The Trade and Globalization Adjustment Assistance... DEPARTMENT OF LABOR Employment and Training Administration Trade Adjustment Assistance Program; Designation of Certifying Officers AGENCY: Employment and Training Administration, Labor. ACTION: Notice...

  7. 77 FR 31875 - Certain Electronic Imaging Devices; Notice of Receipt of Complaint; Solicitation of Comments...

    Science.gov (United States)

    2012-05-30

    ... INTERNATIONAL TRADE COMMISSION [Docket No. 2898] Certain Electronic Imaging Devices; Notice of... Trade Commission. ACTION: Notice. SUMMARY: Notice is hereby given that the U.S. International Trade Commission has received a complaint entitled Certain Electronic Imaging Devices, DN 2898; the Commission is...

  8. 17 CFR 4.32 - Trading on a Registered Derivatives Transaction Execution Facility for Non-Institutional Customers.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Trading on a Registered Derivatives Transaction Execution Facility for Non-Institutional Customers. 4.32 Section 4.32 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION COMMODITY POOL OPERATORS AND COMMODITY TRADING...

  9. Plasma HDL-cholesterol and triglycerides, but not LDL-cholesterol, are associated with insulin secretion in non-diabetic subjects.

    Science.gov (United States)

    Natali, Andrea; Baldi, Simona; Bonnet, Fabrice; Petrie, John; Trifirò, Silvia; Tricò, Domenico; Mari, Andrea

    2017-04-01

    Experimental data support the notion that lipoproteins might directly affect beta cell function, however clinical data are sparse and inconsistent. We aimed at verifying whether, independently of major confounders, serum lipids are associated with alterations in insulin secretion or clearance non-diabetic subjects. Cross sectional and observational prospective (3.5yrs), multicentre study in which 1016 non-diabetic volunteers aged 30-60yrs. and with a wide range of BMI (20.0-39.9kg/m 2 ) were recruited in a setting of University hospital ambulatory care (RISC study). baseline fasting lipids, fasting and OGTT-induced insulin secretion and clearance (measured by glucose and C-peptide modeling), peripheral insulin sensitivity (by the euglycemic clamp). Lipids and OGTT were repeated in 980 subjects after 3.5years. LDL-cholesterol did not show independent associations with fasting or stimulated insulin secretion or clearance. After accounting for potential confounders, HDL-cholesterol displayed negative and triglycerides positive independent associations with fasting and OGTT insulin secretion; neither with insulin clearance. Low HDL-cholesterol and high triglycerides were associated with an increase in glucose-dependent and a decrease in non-glucose-dependent insulin secretion. Over 3.5years both an HDL-cholesterol decline and a triglycerides rise were associated with an increase in fasting insulin secretion independent of changes in body weight or plasma glucose. LDL-cholesterol does not seem to influence any major determinant of insulin bioavailability while low HDL-cholesterol and high triglycerides might contribute to sustain the abnormalities in insulin secretion that characterize the pre-diabetic state. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. 78 FR 76655 - Notice of Receipt of Complaint; Solicitation of Comments Relating to the Public Interest

    Science.gov (United States)

    2013-12-18

    ... Trade Commission (USITC): http://edis.usitc.gov . \\3\\ Electronic Document Information System (EDIS... INTERNATIONAL TRADE COMMISSION Notice of Receipt of Complaint; Solicitation of Comments Relating to the Public Interest AGENCY: U.S. International Trade Commission. ACTION: Notice. SUMMARY: Notice...

  11. 75 FR 44762 - Export Trade Certificate of Review

    Science.gov (United States)

    2010-07-29

    ... Competition and Economic Analysis (``OCEA'') of the International Trade Administration, U.S. Department of..., Office of Competition and Economic Analysis, International Trade Administration, (202) 482-5131 (this is... later than 20 days after the date of this notice to: Office of Competition and Economic Analysis...

  12. The Secret Driving Force Behind Mongolia’s Successful Democracy

    Science.gov (United States)

    2016-03-01

    the nation’s democracy movement its earliest stages. Courtesy of the Democratic Union of Mongolia PRISM 6, no. 1 FROM THE FIELD | 141 The Secret Driving...assistance and trade. Our state budget PRISM 6, no. 1 FROM THE FIELD | 143 THE SECRET DRIVING FORCE BEHIND MONGOLIA’S SUCCESSFUL DEMOCRACY collapsed; we...O yungerel Tsedevdam ba (2006) PRISM 6, no. 1 FROM THE FIELD | 145 THE SECRET DRIVING FORCE BEHIND MONGOLIA’S SUCCESSFUL DEMOCRACY significantly as

  13. 78 FR 116 - Certain Cases for Portable Electronic Devices: Notice of Receipt of Complaint; Solicitation of...

    Science.gov (United States)

    2013-01-02

    ... INTERNATIONAL TRADE COMMISSION [DN 2927] Certain Cases for Portable Electronic Devices: Notice of Receipt of Complaint; Solicitation of Comments Relating to the Public Interest AGENCY: International Trade Commission. ACTION: Notice. SUMMARY: Notice is hereby given that the U.S. International Trade Commission has...

  14. 78 FR 4167 - Certain Electronic Bark Control Collars; Notice of Receipt of Complaint; Solicitation of Comments...

    Science.gov (United States)

    2013-01-18

    ... INTERNATIONAL TRADE COMMISSION [Docket No. 2932] Certain Electronic Bark Control Collars; Notice.... International Trade Commission. ACTION: Notice. SUMMARY: Notice is hereby given that the U.S. International Trade Commission has received a complaint entitled Certain Electronic Bark Control Collars, DN 2932; the...

  15. 16 CFR 14.12 - Use of secret coding in marketing research.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Use of secret coding in marketing research... STATEMENTS § 14.12 Use of secret coding in marketing research. (a) The Federal Trade Commission has determined to close its industry-wide investigation of marketing research firms that was initiated in...

  16. Tools for Trade Analysis and Open Source Information Monitoring for Non-proliferation

    International Nuclear Information System (INIS)

    Cojazzi, G.G.M.; Versino, C.; Wolfart, E.; Renda, G.; Janssens, W.A.M.; )

    2015-01-01

    The new state level approach being proposed by IAEA envisions an objective based and information driven safeguards approach utilizing all relevant information to improve the effectiveness and efficiency of safeguards. To this goal the IAEA makes also use of open source information, here broadly defined as any information that is neither classified nor proprietary. It includes, but is not limited to: media sources, government and non-governmental reports and analyzes, commercial data, and scientific/technical literature, including trade data. Within the EC support programme to IAEA, JRC has surveyed and catalogued open sources on import-export customs trade data and developed tools for supporting the use of the related databases in safeguards. The JRC software The Big Table, (TBT), supports i.a.: a) the search through a collection of reference documents relevant to trade analysis (legal/regulatory documents, technical handbooks); b) the selection of items of interests to specific verifications and c) the mapping of these items to customs commodities searchable in trade databases. In the field of open source monitoring, JRC is developing and operating a ''Nuclear Security Media Monitor'' (NSMM), which is a web-based multilingual news aggregation system that automatically collects news articles from pre-defined web sites. NSMM is a domain specific version of the general JRC-Europe Media Monitor (EMM). NSMM has been established within the EC support programme with the aim, i.e., to streamline IAEA's process of open source information monitoring. In the first part, the paper will recall the trade data sources relevant for non-proliferation and will then illustrate the main features of TBT, recently coupled with the IAEA Physical Model, and new visualization techniques applied to trade data. In the second part it will present the main aspects of the NSMM also by illustrating some of uses done at JRC. (author)

  17. 75 FR 43485 - Trade Adjustment Assistance for Farmers

    Science.gov (United States)

    2010-07-26

    ... Service Trade Adjustment Assistance for Farmers AGENCY: Foreign Agricultural Service, USDA. ACTION: Notice... cash benefits. FOR FURTHER INFORMATION CONTACT: Trade Adjustment Assistance for Farmers Staff, FAS... visit the TAA for Farmers' Web site: http://www.fas.usda.gov/itp/taa . Dated: July 14, 2010. John D...

  18. 78 FR 69047 - Travel and Tourism Trade Mission to Taiwan, Japan and Korea

    Science.gov (United States)

    2013-11-18

    ... DEPARTMENT OF COMMERCE International Trade Administration Travel and Tourism Trade Mission to Taiwan, Japan and Korea AGENCY: International Trade Administration, Department of Commerce. ACTION... Foreign Commercial Service is amending notice [[Page 69048

  19. 40 CFR 350.7 - Substantiating claims of trade secrecy.

    Science.gov (United States)

    2010-07-01

    ... publications or other information sources available to the public or your competitors (of which you are aware... of the chemical claimed as trade secret and explain why it is a secret of interest to competitors... competitors could deduce this use from disclosure of the chemical identity together with other information on...

  20. 76 FR 7152 - ICT Trade Mission to Saudi Arabia; Application Deadline Extended

    Science.gov (United States)

    2011-02-09

    ... DEPARTMENT OF COMMERCE International Trade Administration ICT Trade Mission to Saudi Arabia; Application Deadline Extended AGENCY: International Trade Administration, Department of Commerce. ACTION: Notice. Timeframe for Recruitment and Applications Mission recruitment will be conducted in an open and...

  1. Value and limitations of CT scan in adulthood non-secreting adrenal gland disorders. Report of sixty-seven cases

    International Nuclear Information System (INIS)

    Laissy, J.P.; Roussel, F.; Genevois, A.; Benozio, M.; Fournier, L.; Denizet, D.; Clement, J.F.

    1989-01-01

    The sensitivity and specificity of CT scan in 67 adults with non-secreting adrenal gland disorders are studied. Whereas corticoadrenal carcinomas are readily recognized, diagnosis of non-secreting adrenal masses in patients with evidence of cancer or in symptom-free subjects is more difficult. According to the results, the only sign that specifically indicates malignancy is heterogeneity following intravenous injection of the contrast medium. This criterion is often inconclusive, making other diagnostic procedures necessary [fr

  2. Value and limitations of CT scan in adulthood non-secreting adrenal gland disorders. Report of sixty-seven cases

    Energy Technology Data Exchange (ETDEWEB)

    Laissy, J.P.; Roussel, F.; Genevois, A.; Benozio, M.; Fournier, L.; Denizet, D.; Clement, J.F.

    1989-04-01

    The sensitivity and specificity of CT scan in 67 adults with non-secreting adrenal gland disorders are studied. Whereas corticoadrenal carcinomas are readily recognized, diagnosis of non-secreting adrenal masses in patients with evidence of cancer or in symptom-free subjects is more difficult. According to the results, the only sign that specifically indicates malignancy is heterogeneity following intravenous injection of the contrast medium. This criterion is often inconclusive, making other diagnostic procedures necessary.

  3. Trade creation and trade diversion in the Canada - United States Free Trade Agreement

    OpenAIRE

    Kimberly A. Clausing

    2001-01-01

    In this paper the changes in trade patterns introduced by the Canada-United States Free Trade Agreement are examined. Variation in the extent of tariff liberalization under the agreement is used to identify the impact of tariff liberalization on the growth of trade both with member countries and non-member countries. Data at the commodity level are used, and the results indicate that the Canada-United States Free Trade Agreement had substantial trade creation effects, with little evidence of ...

  4. 76 FR 33700 - Agricultural Policy Advisory Committee for Trade; Renewal

    Science.gov (United States)

    2011-06-09

    ...Pursuant to the Federal Advisory Committee Act, notice is hereby given that the Secretary of Agriculture (Secretary), in coordination with the United States Trade Representative (USTR), has renewed the Agricultural Policy Advisory Committee for Trade (APAC).

  5. Effect of fenspiride, a non-steroidal antiinflammatory agent, on neurogenic mucus secretion in ferret trachea in vitro.

    Science.gov (United States)

    Khawaja, A M; Liu, Y C; Rogers, D F

    1999-01-01

    Neural mechanisms contribute to control of mucus secretion in the airways. Fenspiride is a non-steroidal antiinflammatory agent which has a variety of actions, including inhibition of neurogenic bronchoconstriction. The effect of fenspiride on neurally-mediated mucus secretion was investigated in vitro in electrically-stimulated ferret trachea, using(35)SO(4)as a mucus marker. Cholinergic secretory responses were isolated using adrenoceptor and tachykinin receptor antagonists. Tachykinin responses were isolated using cholinoceptor and adrenoceptor antagonists. Electrical stimulation increased cholinergic secretion by;90% and tachykininergic secretion by;40%. Fenspiride (1 microM-1 mM) tended to inhibit cholinergic secretion in a concentration-dependent manner, although only at 1 mM was inhibition (by 87%) significant. Inhibition by fenspiride of tachykininergic secretion was not concentration-dependent, and again significant inhibition (by 85%) was only at 1 mM. Inhibition was not due to loss of tissue viability, as assessed by restitution of secretory response after washout. Fenspiride also inhibited secretion induced by acetylcholine, but did not inhibit substance P-induced secretion. Histamine receptor antagonists increased basal secretion by 164%, whereas fenspiride did not affect basal secretion. We conclude that, in ferret trachea in vitro, fenspiride inhibits neurally-mediated mucus secretion, with antimuscarinic action the most plausible mechanism of action, but not necessarily the only mechanism. Copyright 1999 Academic Press.

  6. 76 FR 70709 - Sunshine Act Meeting; Emergency Meeting Notice

    Science.gov (United States)

    2011-11-15

    ... COMMODITY FUTURES TRADING COMMISSION Sunshine Act Meeting; Emergency Meeting Notice This notice that an emergency meeting was held is published pursuant to the provisions of the Government in the Sunshine Act, Public Law 94-409, 5 U.S.C. 552b. AGENCY HOLDING THE MEETING: Commodity Futures Trading...

  7. Quantum secret sharing with classical Bobs

    International Nuclear Information System (INIS)

    Li Lvzhou; Qiu Daowen; Mateus, Paulo

    2013-01-01

    Boyer et al (2007 Phys. Rev. Lett. 99 140501) proposed a novel idea of semi-quantum key distribution, where a key can be securely distributed between Alice, who can perform any quantum operation, and Bob, who is classical. Extending the ‘semi-quantum’ idea to other tasks of quantum information processing is of interest and worth considering. In this paper, we consider the issue of semi-quantum secret sharing, where a quantum participant Alice can share a secret key with two classical participants, Bobs. After analyzing the existing protocol, we propose a new protocol of semi-quantum secret sharing. Our protocol is more realistic, since it utilizes product states instead of entangled states. We prove that any attempt of an adversary to obtain information necessarily induces some errors that the legitimate users could notice. (paper)

  8. 78 FR 42041 - Travel and Tourism Trade Mission to Taiwan, Japan, and Korea

    Science.gov (United States)

    2013-07-15

    ... DEPARTMENT OF COMMERCE International Trade Administration Travel and Tourism Trade Mission to... Foreign Commercial Service is amending notice for the Travel and Tourism Trade Mission to Taiwan, Japan... executive lead the Travel and Tourism Trade Mission to Taiwan, Japan and Korea, March 10-14, 2014, published...

  9. 27 CFR 44.264a - To a foreign-trade zone.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false To a foreign-trade zone. 44.264a Section 44.264a Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE... Warehouses Notice of Removal of Shipment § 44.264a To a foreign-trade zone. Where cigars are withdrawn from a...

  10. 75 FR 55739 - Export Trade Certificate of Review

    Science.gov (United States)

    2010-09-14

    ..., Canada; Broad Reach Engineering Company, Golden, CO; Celestica Corporation, Toronto, Canada; Deloitte... INFORMATION: Title III of the Export Trading Company Act of 1982 (15 U.S.C. 4001-21) authorizes the Secretary... Trading Company Act of 1982 and 15 CFR 325.6(a) requires the Secretary to publish a notice in the Federal...

  11. 77 FR 75997 - Environmental Technologies Trade Advisory Committee (ETTAC), Request for Nominations from U.S...

    Science.gov (United States)

    2012-12-26

    ... DEPARTMENT OF COMMERCE International Trade Administration Environmental Technologies Trade... Environmental Technologies Trade Advisory Committee (ETTAC). SUMMARY: This notice sets forth a request for... serve on the Environmental Technologies Trade Advisory Committee (ETTAC). One person will be appointed...

  12. 77 FR 32995 - Certain Electronic Imaging Devices Corrected: Notice of Receipt of Complaint; Solicitation of...

    Science.gov (United States)

    2012-06-04

    ... INTERNATIONAL TRADE COMMISSION [Docket No. 2898] Certain Electronic Imaging Devices Corrected.... International Trade Commission. ACTION: Notice. SUMMARY: Notice is hereby given that the U.S. International Trade Commission has received a complaint entitled Certain Electronic Imaging Devices, DN 2898; the...

  13. Implications of the World Trade Organization in combating non-communicable diseases.

    Science.gov (United States)

    Mitchell, A; Voon, T

    2011-12-01

    The World Health Organization (WHO) has proposed a number of strategies to combat non-communicable diseases such as cancers, cardiovascular diseases, chronic respiratory diseases and diabetes by targeting the risk factors of tobacco use, harmful use of alcohol and poor diet. A number of the domestic regulatory responses contemplated by WHO and individual countries have the potential to restrict or distort trade, raising the question of whether they are consistent with the obligations imposed on Members of the World Trade Organization (WTO). This article demonstrates that WTO rules do limit Members' flexibility in implementing public health measures to address these diseases. However, the focus of WTO provisions on preventing discrimination against or between imports and the exceptions incorporated in various WTO agreements leave sufficient scope for Members to design carefully directed measures to achieve genuine public health goals while minimizing negative effects on international trade. Copyright © 2011 The Royal Society for Public Health. Published by Elsevier Ltd. All rights reserved.

  14. 77 FR 4582 - Certain Mobile Devices and Related Software Corrected Notice of Request for Statements on the...

    Science.gov (United States)

    2012-01-30

    ... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-750] Certain Mobile Devices and Related Software Corrected Notice of Request for Statements on the Public Interest AGENCY: U.S. International Trade Commission. ACTION: Correction to Notice. SUMMARY: This Notice corrects the notice in the same matter...

  15. 78 FR 2437 - Corrected: Certain Cases For Portable Electronic Devices; Notice of Receipt of Complaint...

    Science.gov (United States)

    2013-01-11

    ... INTERNATIONAL TRADE COMMISSION [Docket No. 2927] Corrected: Certain Cases For Portable Electronic...: U.S. International Trade Commission. ACTION: Notice. SUMMARY: Notice is hereby given that the U.S. International Trade Commission has received a complaint entitled Certain Cases For Portable Electronic Devices...

  16. 75 FR 4449 - Requested Administrative Waiver of the Coastwise Trade Laws

    Science.gov (United States)

    2010-01-27

    ... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2010-0002] Requested Administrative Waiver of the Coastwise Trade Laws AGENCY: Maritime Administration, Department of Transportation. ACTION: Notice; correction. SUMMARY: On January 15, 2010, the Maritime Administration published notice of...

  17. 75 FR 43939 - The Americas Business Trade Mission to Mexico

    Science.gov (United States)

    2010-07-27

    ... Mexico AGENCY: International Trade Administration, Department of Commerce. ACTION: Notice. Mission... will recruit and organize a multiple industry trade mission to Mexico City with an optional second stop... local business climate. In Mexico City, there will also be a networking reception for the delegation...

  18. 15 CFR 990.44 - Notice of Intent to Conduct Restoration Planning.

    Science.gov (United States)

    2010-01-01

    ... Foreign Trade (Continued) NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE OIL POLLUTION ACT REGULATIONS NATURAL RESOURCE DAMAGE ASSESSMENTS Preassessment Phase § 990.44 Notice of Intent... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Notice of Intent to Conduct...

  19. 77 FR 66582 - Notice of Request for Information for the Proposed United States-East African Community...

    Science.gov (United States)

    2012-11-06

    ... barriers and other constraints to trade; support the EAC's integration process by facilitating stronger... DEPARTMENT OF COMMERCE International Trade Administration Notice of Request for Information for... Commerce, International Trade Administration. ACTION: Notice of Request for Information. SUMMARY: In June...

  20. 78 FR 12788 - Certain Electronic Bark Control Collars; Notice of Institution of Investigation; Institution of...

    Science.gov (United States)

    2013-02-25

    ... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-870] Certain Electronic Bark Control... AGENCY: U.S. International Trade Commission. ACTION: Notice. SUMMARY: Notice is hereby given that a complaint and a motion for temporary relief were filed with the U.S. International Trade Commission on...

  1. 75 FR 56506 - Beauty and Cosmetics Trade Mission to India; Application Deadline Extended and Acceptance To...

    Science.gov (United States)

    2010-09-16

    ... DEPARTMENT OF COMMERCE International Trade Administration Beauty and Cosmetics Trade Mission to..., direct mail, notices by industry trade associations and other multiplier groups, and publicity at industry meetings, symposia, conferences, and trade shows. The application deadline has been extended to...

  2. 76 FR 50253 - Certain Portable Electronic Devices and Related Software; Notice of Institution of Investigation...

    Science.gov (United States)

    2011-08-12

    ... INTERNATIONAL TRADE COMMISSION [Inv. No. 337-TA-797] Certain Portable Electronic Devices and....C. 1337 AGENCY: U.S. International Trade Commission. ACTION: Notice SUMMARY: Notice is hereby given that a complaint was filed with the U.S. International Trade Commission on July 8, 2011, under section...

  3. 76 FR 47610 - Certain Electronic Digital Media Devices and Components Thereof; Notice of Institution of...

    Science.gov (United States)

    2011-08-05

    ... INTERNATIONAL TRADE COMMISSION [Inv. No. 337-TA-796] Certain Electronic Digital Media Devices and.... 1337 AGENCY: U.S. International Trade Commission. ACTION: Notice. SUMMARY: Notice is hereby given that a complaint was filed with the U.S. International Trade Commission on July 5, 2011, under section...

  4. The relationship between international trade and non-nutritional health outcomes: A systematic review of quantitative studies.

    Science.gov (United States)

    Burns, Darren K; Jones, Andrew P; Suhrcke, Marc

    2016-03-01

    Markets throughout the world have been reducing barriers to international trade and investment in recent years. The resulting increases in levels of international trade and investment have subsequently generated research interest into the potential population health impact. We present a systematic review of quantitative studies investigating the relationship between international trade, foreign direct investment and non-nutritional health outcomes. Articles were systematically collected from the SCOPUS, PubMed, EconLit and Web of Science databases. Due to the heterogeneous nature of the evidence considered, the 16 included articles were subdivided into individual level data analyses, selected country analyses and international panel analyses. Articles were then quality assessed using a tool developed as part of the project. Nine of the studies were assessed to be high quality, six as medium quality, and one as low quality. The evidence from the quantitative literature suggests that overall, there appears to be a beneficial association between international trade and population health. There was also evidence of the importance of foreign direct investment, yet a lack of research considering the direction of causality. Taken together, quantitative research into the relationship between trade and non-nutritional health indicates trade to be beneficial, yet this body of research is still in its infancy. Future quantitative studies based on this foundation will provide a stronger basis on which to inform relevant national and international institutions about the health consequences of trade policies. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. 77 FR 66866 - Certain Computer Forensic Devices and Products Containing the Same Notice of Request for...

    Science.gov (United States)

    2012-11-07

    ... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-799] Certain Computer Forensic Devices and Products Containing the Same Notice of Request for Statements on the Public Interest AGENCY: U.S. International Trade Commission. ACTION: Notice. SUMMARY: Notice is hereby given that the presiding...

  6. Insulin secretion and incretin hormones after oral glucose in non-obese subjects with impaired glucose tolerance

    DEFF Research Database (Denmark)

    Rask, E; Olsson, T; Söderberg, S

    2004-01-01

    of glucose, insulin, C-peptide, GLP-1, and GIP. Insulin secretion (TIS) and insulin sensitivity (OGIS) were assessed using models describing the relationship between glucose, insulin and C-peptide data. These models allowed estimation also of the hepatic extraction of insulin. The age (54.2 +/- 9.7 [mean......Subjects with impaired glucose tolerance (IGT) are usually overweight and exhibit insulin resistance with a defective compensation of insulin secretion. In this study, we sought to establish the interrelation between insulin secretion and insulin sensitivity after oral glucose in non-obese subjects...... over the whole 180-minute period was higher in IGT (26.2 +/- 2.4 v 20.0 +/- 2.0 nmol/L; P =.035). Hepatic insulin extraction correlated linearly with OGIS (r = 0.71; P

  7. Population Ageing and Pension Reform in a Small Open Economy with Non-Traded Goods

    NARCIS (Netherlands)

    L.J.H. Bettendorf (Leon); B.J. Heijdra (Ben)

    2004-01-01

    textabstractIn this paper we study the implications of population ageing in an economy with a sizeable non-traded goods sector. To this effect a highly stylized micro-founded macro model is constructed in which the age structure of the population plays a non-trivial role. The model distinguishes

  8. Population ageing and pension reform in a small open economy with non-traded goods

    NARCIS (Netherlands)

    Bettendorf, Leon J. H.; Heijdra, Ben J.

    2006-01-01

    In this paper we study the implications of population ageing in an economy with a sizeable non-traded goods sector. To this effect a highly stylized micro-founded macro model is constructed in which the age structure of the population plays a non-trivial role. The model distinguishes separate birth

  9. 75 FR 13494 - North American Free-Trade Agreement, Article 1904; NAFTA Panel Reviews; Request for Panel Review

    Science.gov (United States)

    2010-03-22

    ... DEPARTMENT OF COMMERCE International Trade Administration North American Free-Trade Agreement... Secretariat pursuant to Article 1904 of the North American Free Trade Agreement. Panel Review was requested of... Section, International Trade Administration, Department of Commerce. ACTION: Notice of First Request for...

  10. Re-examining the risk–return relationship in Europe: Linear or non-linear trade-off?

    OpenAIRE

    Salvador, Enrique; Floros, Christos; Arago, Vicent

    2014-01-01

    This paper analyzes the risk–return trade-off in Europe using recent data from 11 European stock markets. After relaxing the linear assumptions in the risk–return relationship by introducing a new approach that considers the current state of the market, we obtain significant evidence for a positive risk–return trade-off for low volatility states. However, this finding is reduced or even non-significant during periods of high volatility. Maintaining the linear assumption over the risk–return t...

  11. 26 CFR 1.971-1 - Definitions with respect to export trade corporations.

    Science.gov (United States)

    2010-04-01

    ..., copyrights, secret processes and formulas, goodwill, trademarks, trade brands, franchises, and other like... trade income, the anticipated future needs of the business will be taken into account to the extent that... determination date; anticipated future needs relating to a later period will not be taken into account unless it...

  12. 15 CFR 2003.1 - Notice of public hearings.

    Science.gov (United States)

    2010-01-01

    ... UNITED STATES TRADE REPRESENTATIVE REGULATIONS OF TRADE POLICY STAFF COMMITTEE § 2003.1 Notice of public... generalized tariff preferences for the listed articles; (b) Whenever the Special Representative or the Deputy...

  13. Gravity Models of Trade-based Money Laundering

    NARCIS (Netherlands)

    Ferwerda, J.|info:eu-repo/dai/nl/314405526; Kattenberg, M.A.C.|info:eu-repo/dai/nl/357208986; Chang, H.-S.; Unger, B.|info:eu-repo/dai/nl/290994926; Groot, L.F.M.|info:eu-repo/dai/nl/073642398; Bikker, J.A.|info:eu-repo/dai/nl/06912261X

    2011-01-01

    Several attempts have been made in the economics literature to measure money laundering. However, the adequacy of these models is difficult to assess, as money laundering takes place secretly and, hence, goes unobserved. An exception is tradebased money laundering (TBML), a special form of trade

  14. 76 FR 53154 - In the Matter of Certain Electronic Paper Towel Dispensing Devices and Components Thereof; Notice...

    Science.gov (United States)

    2011-08-25

    ... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-718] In the Matter of Certain Electronic... Section 337 by Defaulting Respondents AGENCY: U.S. International Trade Commission. ACTION: Notice. SUMMARY: Notice is hereby given that the U.S. International Trade Commission has determined not to review an...

  15. Medicinal use of secretions (“the frog vaccine”) from the kambô frog (Phyllomedusa bicolor) by non-indigenous peoples in Rondônia, Brazil

    OpenAIRE

    Paulo Sérgio Bernarde; Rosimeyri Aparecida Santos

    2009-01-01

    Amphibians have pharmaceutically active skin secretions that protect against infections and predation. Some indigenous people in southwestern Amazonia use these secretions from P. bicolor for medicinal purposes. While the use of these secretions by indigenous people is relatively well-known, the use by non-indigenous peoples is very poorly studied. Here we describe the use of the “frog vaccine” by non-indigenous populations in the Brazilian state of Rondônia. Thirty-one people who had receive...

  16. Inhibition of Non Canonical HIV-1 Tat Secretion Through the Cellular Na+,K+-ATPase Blocks HIV-1 Infection

    Directory of Open Access Journals (Sweden)

    Silvia Agostini

    2017-07-01

    Full Text Available Besides its essential role in the activation of HIV-1 gene expression, the viral Tat protein has the unusual property of trafficking in and out of cells. In contrast to Tat internalization, the mechanism involved in extracellular Tat release has so far remained elusive. Here we show that Tat secretion occurs through a Golgi-independent pathway requiring binding of Tat with three short, non-consecutive intracytoplasmic loops at the C-terminus of the cellular Na+,K+-ATPase pump alpha subunit. Ouabain, a pump inhibitor, blocked this interaction and prevented Tat secretion; virions produced in the presence of this drug were less infectious, consistent the capacity of virion-associated Tat to increase HIV-1 infectivity. Treatment of CD4+ T-cells with short peptides corresponding to the Tat-binding regions of the pump alpha subunit impaired extracellular Tat release and blocked HIV-1 replication. Thus, non canonical, extracellular Tat secretion is essential for viral infectivity.

  17. 77 FR 60966 - Executive-Led Trade Mission to South Africa and Zambia

    Science.gov (United States)

    2012-10-05

    ... Africa and Zambia AGENCY: International Trade Administration, Department of Commerce. ACTION: Notice...- Led Trade Mission to South Africa and Zambia scheduled for November 26- 30, 2012, to revise the dates... and scheduling constraints permit), interested U.S. agriculture, mining, transportation, water, energy...

  18. 77 FR 40405 - Notice of a Non-Aeronautical Land-Use Change Effecting the Quitclaim Deed and Federal Grant...

    Science.gov (United States)

    2012-07-09

    ... the application for a non-aeronautical land- use change for approximately 38 acres of airport property... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Notice of a Non-Aeronautical Land-Use..., Delano, CA AGENCY: Federal Aviation Administration, DOT. ACTION: Notice of a Non-Aeronautical Land-Use...

  19. 77 FR 13173 - Notice of a Non-Aeronautical Land-Use Change Effecting the Quitclaim Deed and Federal Grant...

    Science.gov (United States)

    2012-03-05

    ... AGENCY: Federal Aviation Administration, DOT. ACTION: Notice of a Non-aeronautical land-use change... application for a non-aeronautical land- use change for approximately 829 acres of airport property at Blythe... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Notice of a Non-Aeronautical Land-Use...

  20. 78 FR 18317 - U.S. Healthcare Trade Mission to Russia- Amendment

    Science.gov (United States)

    2013-03-26

    ... DEPARTMENT OF COMMERCE International Trade Administration U.S. Healthcare Trade Mission to Russia... Russia published at 77 FR 77032, December 31, 2012, to amend the Notice to revise the dates of the... additional time is needed to allow for additional recruitment and marketing in support of the mission...

  1. Photoacoustic analysis of the solubilization kinetics of pulmonary secretions from cystic fibrosis patients - secretor and non-secretor phenotypes

    Energy Technology Data Exchange (ETDEWEB)

    Barja, P R; Coelho, C C; Paiva, R F [Research and Development Institute, UNIVAP, Av. Shishima Hifumi 2911, Sao Jose dos Campos, SP (Brazil); Barboza, M A; Matos, L C; Matos, C C B [Faculty of Medicine of Sao Jose do Rio Preto (FAMERP), Sao Jose do Rio Preto, SP (Brazil); Oliveira, L V F, E-mail: barja@univap.b [Rehabilitation Sciences Master' s Program, Nove de Julho University (UNINOVE), Sao Paulo, SP (Brazil)

    2010-03-01

    Cystic fibrosis (CF) is an autosomal recessive inherited disease that increases viscoelasticity of pulmonary secretions. Affected patients are required to use therapeutic aerosols continuously. The expression of ABH glycoconjugates in exocrine secretions determines the nature of part of the carbohydrates present in these secretions, allowing the classification of individuals into the so-called 'secretor' and 'non secretor' phenotypes. The aim of this work was to employ photoacoustic (PA) measurements to monitor the solubilization kinetics of pulmonary secretions from CF patients, analyzing the influence of the secretor status in the solubilization kinetics of samples nebulized with different therapeutic aerosols. Sputum samples were obtained by spontaneous expectoration from positive and negative secretor CF patients. Each sample was nebulized with i) tobramycin, ii) alpha dornase, and iii) N-acetylcysteine in a PA cell; fitting of the data with the Boltzmann equation led to the determination of t{sub 0} (typical interaction time) and {Delta}t (solubilization interval) for each curve. Differences between the secretor and non-secretor phenotypes were statistically significant in the groups for tobramycin and alpha dornase, but not for N-acetylcysteine. Results show that the secretor status influences the solubilization of pulmonary mucus of CF patients nebulized with tobramycin and alpha dornase.

  2. The environmental Kuznets curve, economic growth, renewable and non-renewable energy, and trade in Tunisia

    OpenAIRE

    Ben Jebli, Mehdi; Ben Youssef, Slim

    2013-01-01

    We use the autoregressive distributed lag (ARDL) bounds testing approach for cointegration with structural breaks and the vector error correction model (VECM) Granger causality approach in order to investigate relationships between per capita CO2 emissions, GDP, renewable and non-renewable energy consumption and international trade (exports or imports) for Tunisia during the period 1980-2009. We show the existence of a short-run unidirectional causality running from trade, GDP, CO2 emission a...

  3. 75 FR 3721 - Combined Notice of Filings #1

    Science.gov (United States)

    2010-01-22

    ... Trading GP. Description: BNP Paribas Energy Trading GP submits a Tariff Amendment and Notice of Succession... Paragraph 36 of October 15 2009 Order on 2010 Business Plans Nad Budgets. Filed Date: 01/11/2010. Accession...

  4. Spirits Trade After Reform in 1863: To the Issue of Efficiency of State Regulation of Spirits Turnover in Terms of Free Trade

    Directory of Open Access Journals (Sweden)

    Natalia Ye. Goryushkina

    2015-12-01

    Full Text Available On the grounds of published and non-published archive materials the article estimates efficiency of state regulation of spirits turnover in terms of excise taxation period. It also states types of spirits trade, types of public houses, groups of people that have obtained the right for wholesale, retail and that of small amount tradeoff spirits. License gaining procedures are widely described as well. The author pays significant attention to the areas in cities and countryside, where the public houses should not have been opened as well as the individuals who were admitted to spirits trade; also he states events which influenced the sale of spirits. The requirements to interior of public houses, working hours, quality and volumes of trade are also specified. It is pointed out that the officials of excise tax board were to control the regulations of spirit trade, their authority extended to public houses control in 1885. The author comes to the conclusion that regulatory means of excise tax was efficient and by increasing and decreasing of license cost, complication and simplification of new public houses opening all together allowed to regulate the turnover of spirits in terms of free trade thus influencing the number, types, density, range and quality of spirits. However, there was distinct ambiguity in Ministry of Finance policy during the stated excise taxation period. On the one hand it limited free sale of spirits, eradicating public houses which were considered detrimental. On the other hand, the Ministry was set not to notice abuse in trade which gave the opportunity to gain greater benefits at public cost from spirits sales.

  5. A new potential secretion pathway for recombinant proteins in Bacillus subtilis.

    Science.gov (United States)

    Wang, Guangqiang; Xia, Yongjun; Gu, Zhennan; Zhang, Hao; Chen, Yong Q; Chen, Haiqin; Ai, Lianzhong; Chen, Wei

    2015-11-10

    Secretion of cytoplasmic expressed proteins into growth media has significant advantages. Due to the lack of an outer membrane, Bacillus subtilis is considered as a desirable 'cell factory' for the secretion of recombinant proteins. However, bottlenecks in the classical pathway for the secretion of recombinant proteins limit its use on a wide scale. In this study, we attempted to use four typical non-classically secreted proteins as signals to export three recombinant model proteins to the culture medium. All four non-classically secreted proteins can direct the export of the intrinsically disordered nucleoskeletal-like protein (Nsp). Two of them can guide the secretion of alkaline phosphatase (PhoA). One can lead the secretion of the thermostable β-galactosidase BgaB, which cannot be secreted with the aid of typical Sec-dependent signal peptides. Our results show that the non-classically secreted proteins lead the recombinant proteins to the culture medium, and thus non-classical protein secretion pathways can be exploited as a novel secretion pathway for recombinant proteins.

  6. 15 CFR 904.501 - Notice of seizure.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 3 2010-01-01 2010-01-01 false Notice of seizure. 904.501 Section 904... Seizure and Forfeiture Procedures § 904.501 Notice of seizure. Within 60 days from the date of the seizure, NOAA will serve the Notice of Seizure as provided in § 904.3 to the owner or consignee, if known or...

  7. The effect of historical, non-fiction, trade books on third-grade students' perceptions of scientists

    Science.gov (United States)

    Farland, Donna Lynn

    Researchers do not know what, if any, specific influence such stereotypical images have on the shaping of children's perceptions in science (Schibeci & Sorenson, 1983), but the indications are that stereotypical images translate into negative perceptions of science. Commonly held stereotypic images are in direct opposition to what students should understand about science as identified by the National Science Education Standards (1996) in which learning about 'Science as a Human Endeavor' begins as early as grades K--4. Nationally, many schools are moving toward kit-based science instruction, which generally consists of a series of guided discovery activities that lead children toward description and understanding of scientific phenomena. It is proposed that by supplementing these kits with historical, non-fiction, trade books, children will gain a broader understanding of the diversity of scientists, their work, and the variety of places science is done. No studies, to date, have been conducted to examine students' understanding of the concepts included in 'Science as a Human Endeavor' as they receive kit-based science instruction. This research has been designed to answer the following question: Does the inclusion of historical, non-fiction, trade books, presenting scientists as people working with or developing an idea, as part of kit-based science instruction influence third grade students' representations of the contemporary scientist and his/her work? It was found that students who were read historical, non-fiction, trade books in conjunction with kit-based instruction demonstrated significant differences in their drawings of scientists from those produced by students who were not exposed to the trade books with respect to two criteria; appearance of scientists, and the activity performed by scientists. This study also revealed that students were able to maintain the improvement in their representations of scientists four weeks after the intervention had ended

  8. Lower values of VEGF in endometrial secretion are a possible cause of subfertility in non-atopic asthmatic patients

    DEFF Research Database (Denmark)

    Gade, Elisabeth Juul; Thomsen, Simon Francis; Lindenberg, Svend

    2015-01-01

    Abstract Objective: Using endometrial secretion analysis, we assessed whether altered inflammatory cytokine levels can be detected in the uterine environment in asthma patients, thereby providing a possible cause of reduced fertility in asthmatics. Methods: Forty-four unexplained infertile women...... no effect on VEGF levels in uteri. Serum high sensitivity CRP was negatively correlated with VEGF in endometrial secretions. No other significant correlations were observed between peripheral blood values and markers found in utero. Conclusion: Asthma is associated with lower values of VEGF in uterine...... endometrial secretions, which might affect the receptiveness of the endometrium and thereby increase time to pregnancy. The effect appears to be associated with non-atopic asthma with general increased systemic inflammation....

  9. International trade and employment: trade partner country effects on jobs and wages

    NARCIS (Netherlands)

    Fortanier, F.N.; Jaarsma, M.; Korvorst, M.

    2011-01-01

    Recent academic research has consistently identified trading firms - both exporters and importers - to be larger, and to pay higher wages than their non-trading counterparts. However, not all trade is equal: imports from low-wage countries may destroy employment, particularly among low-skilled

  10. 17 CFR 8.11 - Notice of charges.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Notice of charges. 8.11 Section 8.11 Commodity and Securities Exchanges COMMODITY FUTURES TRADING COMMISSION EXCHANGE PROCEDURES FOR DISCIPLINARY, SUMMARY, AND MEMBERSHIP DENIAL ACTIONS Disciplinary Procedure § 8.11 Notice of...

  11. 75 FR 14159 - Notice of Agreements Filed

    Science.gov (United States)

    2010-03-24

    ... parties to exchange slots in the trade between U.S. East Coast ports and ports in Turkey. Agreement No.: 201048-005. Title: Lease and Operating Agreement between Philadelphia Regional Port Authority and... FEDERAL MARITIME COMMISSION Notice of Agreements Filed The Commission hereby gives notice of the...

  12. 27 CFR 70.82 - Payment on notice and demand.

    Science.gov (United States)

    2010-04-01

    ... demand. 70.82 Section 70.82 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE... Collection of Excise and Special (Occupational) Tax Notice and Demand § 70.82 Payment on notice and demand. Upon receipt of notice and demand from the appropriate TTB officer, there shall be paid at the place...

  13. Testing the assumptions behind emissions trading in non-market goods: the RECLAIM program in Southern California

    International Nuclear Information System (INIS)

    Lejano, Raul P.; Hirose, Rei

    2005-01-01

    Emissions trading is, essentially, a policy instrument that is designed to simulate a market for an otherwise public good. Conceptually, its justification hinges on a number of key assumptions, namely the negligibility of local impacts, the ability to separate and commodify the good in question, and characteristics of a well-functioning market. The authors examine the performance of RECLAIM, a NO x emissions trading program in Southern California, USA, and illustrate how to test these assumptions. There is some evidence that the trading of NO x generates new externalities, such as the possibility that other air pollutants, e.g. volatile organics, are essentially traded along with it. Moreover, the RECLAIM program has recently begun to experience difficulties due to the fact that the market is relatively thin. This analysis provides ways to assess more deeply and reform these trading regimes, including opening up RECLAIM to public review. The case study speaks to a wider arena, as emissions trading is presently being considered in other parts of the world to address issues ranging from acid rain to non-point source pollution to greenhouse gases. The analytic approach, illustrated herein, is a general one that has a wider applicability than the particular case of NO x trading. It is hoped that this kind of critical inquiry can lead to a more careful deliberation of the merits and challenges of emissions trading

  14. The Outlier Sectors: Areas of Non-Free Trade in the North American Free Trade Agreement

    OpenAIRE

    Eric T. Miller

    2002-01-01

    Since its entry into force, the North American Free Trade Agreement (NAFTA) has been enormously influential as a model for trade liberalization. While trade in goods among Canada, the United States and Mexico has been liberalized to a significant degree, this most famous of agreements nonetheless contains areas of recalcitrant protectionism. The first part of this paper identifies these "outlier sectors" and classifies them by primary source advocating protectionism, i.e., producer interests ...

  15. Humidification and secretion volume in mechanically ventilated patients.

    Science.gov (United States)

    Solomita, Mario; Palmer, Lucy B; Daroowalla, Feroza; Liu, Jeffrey; Miller, Dori; LeBlanc, Deniese S; Smaldone, Gerald C

    2009-10-01

    To determine potential effects of humidification on the volume of airway secretions in mechanically ventilated patients. Water vapor delivery from devices providing non-heated-wire humidification, heated-wire humidification, and heat and moisture exchanger (HME) were quantified on the bench. Then, patients requiring 24-hour mechanical ventilation were exposed sequentially to each of these humidification devices, and secretions were removed and measured by suctioning every hour during the last 4 hours of the 24-hour study period. In vitro water vapor delivery was greater using non-heated-wire humidification, compared to heated-wire humidification and HME. In vivo, a total of 9 patients were studied. Secretion volume following humidification by non-heated-wire humidification was significantly greater than for heated-wire humidification and HME (P=.004). The volume of secretions appeared to be linked to humidification, as greater water vapor delivery measured in vitro was associated with greater secretion volume in vivo.

  16. Ectosomes: a new mechanism for non-exosomal secretion of tau protein.

    Directory of Open Access Journals (Sweden)

    Simon Dujardin

    Full Text Available Tau is a microtubule-associated protein that aggregates in neurodegenerative disorders known as tauopathies. Recently, studies have suggested that Tau may be secreted and play a role in neural network signalling. However, once deregulated, secreted Tau may also participate in the spreading of Tau pathology in hierarchical pathways of neurodegeneration. The mechanisms underlying neuron-to-neuron Tau transfer are still unknown; given the known role of extra-cellular vesicles in cell-to-cell communication, we wondered whether these vesicles could carry secreted Tau. We found, among vesicles, that Tau is predominately secreted in ectosomes, which are plasma membrane-originating vesicles, and when it accumulates, the exosomal pathway is activated.

  17. 40 CFR 141.209 - Special notice for nitrate exceedances above MCL by non-community water systems (NCWS), where...

    Science.gov (United States)

    2010-07-01

    ... Water Violations § 141.209 Special notice for nitrate exceedances above MCL by non-community water... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Special notice for nitrate exceedances above MCL by non-community water systems (NCWS), where granted permission by the primacy agency under Â...

  18. 77 FR 34127 - Notice of Open Public Hearing

    Science.gov (United States)

    2012-06-08

    ... trade and economic relationship with China. The June 14 hearing is aimed at sharpening our understanding... U.S.-CHINA ECONOMIC AND SECURITY REVIEW COMMISSION Notice of Open Public Hearing AGENCY: U.S.-China Economic and Security Review Commission. ACTION: Notice of open public hearing--June 14, 2012...

  19. 75 FR 13484 - Foreign-Trade Zone 22; Temporary/Interim Manufacturing Authority; LG Electronics Mobilecomm USA...

    Science.gov (United States)

    2010-03-22

    ... DEPARTMENT OF COMMERCE [Docket T-1-2010] Foreign-Trade Zones Board Foreign-Trade Zone 22; Temporary/Interim Manufacturing Authority; LG Electronics Mobilecomm USA, Inc. (Cell Phones); Notice of.../ interim manufacturing (T/IM) authority, on behalf of LG Electronics Mobilecomm USA, Inc. (LGEMU), to...

  20. 76 FR 11424 - Notice of Petitions by Firms for Determination of Eligibility To Apply for Trade Adjustment...

    Science.gov (United States)

    2011-03-02

    ... Administration, Department of Commerce. ACTION: Notice and Opportunity for Public Comment. Pursuant to Section.... variety of custom and in-stock solutions for retail and non-retail environments. Their display, power and... for transportation, mining and industrial machinery. Supreme Manufacturing Company, 1755 Birchwood...

  1. 76 FR 67165 - Combined Notice of Filings #1

    Science.gov (United States)

    2011-10-31

    ... Thursday, November 10, 2011. Docket Numbers: ER12-141-000. Applicants: NAP Trading and Marketing, Inc. Description: NAP Trading and Marketing, Inc submits Notice of Cancellation of Market-Based Rate Tariff to be... of Affiliate Restrictions to be effective 10/20/2011. Filed Date: 10/20/2011. Accession Number...

  2. 75 FR 64248 - Approval for Manufacturing Authority Foreign-Trade Zone 196 ATC Logistics & Electronics (Cell...

    Science.gov (United States)

    2010-10-19

    ... Authority Foreign-Trade Zone 196 ATC Logistics & Electronics (Cell Phone Kitting) Fort Worth, TX Pursuant to... Foreign-Trade Zones Board (the Board) adopts the following Order: Whereas, ATC Logistics & Electronics... Logistics & Electronics, as described in the application and Federal Register notice, is approved, subject...

  3. 77 FR 34935 - Foreign-Trade Zone 161; Temporary/Interim Manufacturing Authority; Siemens Energy, Inc., (Wind...

    Science.gov (United States)

    2012-06-12

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Docket T-4-2012] Foreign-Trade Zone 161; Temporary/Interim Manufacturing Authority; Siemens Energy, Inc., (Wind Turbine Nacelles and Hubs); Notice of... temporary/interim manufacturing (T/IM) authority, on behalf of Siemens Energy, Inc., to manufacture wind...

  4. THE RECENT TREND OF ROMANIA’S INTERNATIONAL TRADE IN GOODS

    Directory of Open Access Journals (Sweden)

    Andrei – Cristian Balasan

    2014-04-01

    Full Text Available The article analyses the recent developments regarding the Romania trade in goods. We highlight how Romania’s trade in goods evolved after the EU accession. In this period Romania’s exports and imports were influenced by the economic crisis, which had a major impact especially on imports. The paper presents the primary trends that have set the volume, dynamics, structure and performance of trade in Romania in the crisis and post-crisis period. We have noticed what changes took place in the structure of exports and imports of goods and also who were the main external partners of Romania.

  5. 78 FR 76818 - U.S. Healthcare Education Trade Mission to New Delhi, Hyderabad, and Ahmedabad, India, January 27...

    Science.gov (United States)

    2013-12-19

    ... DEPARTMENT OF COMMERCE International Trade Administration U.S. Healthcare Education Trade Mission... published a document in the Federal Register of November 13, 2013 regarding the U.S. Healthcare Education..., note a top of page, correct the subject heading of the notice to read: U.S. Healthcare Education Trade...

  6. 15 CFR 19.4 - What notice will Commerce entities send to a debtor when collecting a Commerce debt?

    Science.gov (United States)

    2010-01-01

    ... the Commerce entity intends to garnish the debtor's private sector (i.e., non-Federal) wages (see § 19.... 3201(e); 31 U.S.C. 3720B, 31 CFR 285.13, and § 19.17(a) of this Part); (16) If applicable, the Commerce... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false What notice will Commerce entities...

  7. Clandestine Bushmeat Trade in Cross River State, Nigeria ...

    African Journals Online (AJOL)

    This paper surveyed the herp species traded in secret bush meat markets of Cross River State, with the view of assessing their conservation status and uses they are put to. The study mainly focused on six selected communities in Akamkpa Local Government Area (LGA) of Cross Rivers State, Nigeria – the host LGA of ...

  8. International trade agreements: hazards to health?

    Science.gov (United States)

    Shaffer, Ellen R; Brenner, Joseph E

    2004-01-01

    Since the 1980s, neoliberal policies have prescribed reducing the role of governments, relying on market forces to organize and provide health care and other vital human services. In this context, international trade agreements increasingly serve as mechanisms to enforce the privatization, deregulation, and decentralization of health care and other services, with important implications for democracy as well as for health. Critics contend that social austerity and "free" trade agreements contribute to the rise in global poverty and economic inequality and instability, and therefore to increased preventable illness and death. Under new agreements through the World Trade Organization that cover vital human services such as health care, water, education, and energy, unaccountable, secret trade tribunals could overrule decisions by democratically elected officials on public financing for national health care systems, licensing and training standards for health professionals, patient safety and quality regulations, occupational safety and health, control of hazardous substances such as tobacco and alcohol, the environment, and affordable access to safe water and sanitation. International negotiations in 2003 in Cancun and in Miami suggested that countervailing views are developing momentum. A concerned health care community has begun to call for a moratorium on trade negotiations on health care and water, and to reinvigorate an alternative vision of universal access to vital services.

  9. 75 FR 64742 - Government in the Sunshine Act Meeting Notice

    Science.gov (United States)

    2010-10-20

    ... INTERNATIONAL TRADE COMMISSION [USITC SE-10-029] Government in the Sunshine Act Meeting Notice AGENCY HOLDING THE MEETING: United States International Trade Commission. TIME AND DATE: October 22, 2010... Wireless Communications Devices Featuring Digital Cameras, and Components Thereof). In accordance with...

  10. Multiparty Quantum Secret Sharing of Quantum States Using Entanglement States

    International Nuclear Information System (INIS)

    Ying, Guo; Da-Zu, Huang; Gui-Hua, Zeng; Ho, Lee Moon

    2008-01-01

    A multi-partite-controlled quantum secret sharing scheme using several non-orthogonal entanglement states is presented with unconditional security. In this scheme, the participants share the secret quantum state by exchanging the secret polarization angles of the disordered travel particles. The security of the secret quantum state is also guaranteed by the non-orthogonal multi-partite-controlled entanglement states, the participants' secret polarizations, and the disorder of the travelling particles. Moreover, the present scheme is secure against the particle-number splitting attack and the intercept-and-resend attack. It may be still secure even if the distributed quantum state is embedded in a not-so-weak coherent-state pulse

  11. Quantification of beta-cell function during IVGTT in Type II and non-diabetic subjects: assessment of insulin secretion by mathematical methods

    DEFF Research Database (Denmark)

    Kjems, L L; Vølund, A; Madsbad, Sten

    2001-01-01

    AIMS/HYPOTHESIS: We compared four methods to assess their accuracy in measuring insulin secretion during an intravenous glucose tolerance test in patients with Type II (non-insulin-dependent) diabetes mellitus and with varying beta-cell function and matched control subjects. METHODS: Eight control...... subjects and eight Type II diabetic patients underwent an intravenous glucose tolerance test with tolbutamide and an intravenous bolus injection of C-peptide to assess C-peptide kinetics. Insulin secretion rates were determined by the Eaton deconvolution (reference method), the Insulin SECretion method...... (ISEC) based on population kinetic parameters as well as one-compartment and two-compartment versions of the combined model of insulin and C-peptide kinetics. To allow a comparison of the accuracy of the four methods, fasting rates and amounts of insulin secreted during the first phase (0-10 min...

  12. In vivo Microscopic Photoacoustic Spectroscopy for Non-Invasive Glucose Monitoring Invulnerable to Skin Secretion Products.

    Science.gov (United States)

    Sim, Joo Yong; Ahn, Chang-Geun; Jeong, Eun-Ju; Kim, Bong Kyu

    2018-01-18

    Photoacoustic spectroscopy has been shown to be a promising tool for non-invasive blood glucose monitoring. However, the repeatability of such a method is susceptible to changes in skin condition, which is dependent on hand washing and drying due to the high absorption of infrared excitation light to the skin secretion products or water. In this paper, we present a method to meet the challenges of mid-infrared photoacoustic spectroscopy for non-invasive glucose monitoring. By obtaining the microscopic spatial information of skin during the spectroscopy measurement, the skin region where the infrared spectra is insensitive to skin condition can be locally selected, which enables reliable prediction of the blood glucose level from the photoacoustic spectroscopy signals. Our raster-scan imaging showed that the skin condition for in vivo spectroscopic glucose monitoring had significant inhomogeneities and large variability in the probing area where the signal was acquired. However, the selective localization of the probing led to a reduction in the effects of variability due to the skin secretion product. Looking forward, this technology has broader applications not only in continuous glucose monitoring for diabetic patient care, but in forensic science, the diagnosis of malfunctioning sweat pores, and the discrimination of tumors extracted via biopsy.

  13. The Effects of Secret Instructions and Yes/no Questions on Maltreated and Non-maltreated Children's Reports of a Minor Transgression.

    Science.gov (United States)

    Ahern, Elizabeth C; Stolzenberg, Stacia N; McWilliams, Kelly; Lyon, Thomas D

    2016-11-01

    This study examined the effects of secret instructions (distinguishing between good/bad secrets and encouraging disclosure of bad secrets) and yes/no questions (DID: "Did the toy break?" versus DYR: "Do you remember if the toy broke?") on 262 maltreated and non-maltreated children's (age range 4-9 years) reports of a minor transgression. Over two-thirds of children failed to disclose the transgression in response to free recall (invitations and cued invitations). The secret instruction increased disclosures early in free recall, but was not superior to no instruction when combined with cued invitations. Yes/no questions specifically asking about the transgression elicited disclosures from almost half of the children who had not previously disclosed, and false alarms were rare. DYR questions led to ambiguous responding among a substantial percentage of children, particularly younger children. The findings highlight the difficulties of eliciting transgression disclosures without direct questions. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

  14. 76 FR 67530 - Generalized System of Preferences (GSP): Notice of Actions Arising Out of the 2010 Annual GSP Review

    Science.gov (United States)

    2011-11-01

    ... OFFICE OF THE UNITED STATES TRADE REPRESENTATIVE Generalized System of Preferences (GSP): Notice of Actions Arising Out of the 2010 Annual GSP Review AGENCY: Office of the United States Trade Representative. ACTION: Notice of a petition accepted for review; and request for comments. SUMMARY: In September...

  15. Pituitary-hormone secretion by thyrotropinomas

    OpenAIRE

    Roelfsema, Ferdinand; Kok, Simon; Kok, Petra; Pereira, Alberto M.; Biermasz, Nienke R.; Smit, Jan W.; Frolich, Marijke; Keenan, Daniel M.; Veldhuis, Johannes D.; Romijn, Johannes A.

    2008-01-01

    Hormone secretion by somatotropinomas, corticotropinomas and prolactinomas exhibits increased pulse frequency, basal and pulsatile secretion, accompanied by greater disorderliness. Increased concentrations of growth hormone (GH) or prolactin (PRL) are observed in about 30% of thyrotropinomas leading to acromegaly or disturbed sexual functions beyond thyrotropin (TSH)-induced hyperthyroidism. Regulation of non-TSH pituitary hormones in this context is not well understood. We there therefore ev...

  16. Proton pump inhibitors inhibit pancreatic secretion

    DEFF Research Database (Denmark)

    Wang, Jing; Barbuskaite, Dagne; Tozzi, Marco

    2015-01-01

    +/K+-ATPases are expressed and functional in human pancreatic ducts and whether proton pump inhibitors (PPIs) have effect on those. Here we show that the gastric HKα1 and HKβ subunits (ATP4A; ATP4B) and non-gastric HKα2 subunits (ATP12A) of H+/K+-ATPases are expressed in human pancreatic cells. Pumps have similar...... of major ions in secretion follow similar excretory curves in control and PPI treated animals. In addition to HCO3-, pancreas also secretes K+. In conclusion, this study calls for a revision of the basic model for HCO3- secretion. We propose that proton transport is driving secretion, and that in addition...

  17. 16 CFR 680.26 - Delivery of opt-out notices.

    Science.gov (United States)

    2010-01-01

    ... 680.26 Commercial Practices FEDERAL TRADE COMMISSION THE FAIR CREDIT REPORTING ACT AFFILIATE MARKETING... Internet Web site at which the consumer obtained a product or service electronically and requires the... disclosures by e-mail from the affiliate providing the notice; or (3) Posts the notice on an Internet Web site...

  18. Secret Key Agreement: Fundamental Limits and Practical Challenges

    KAUST Repository

    Rezki, Zouheir

    2017-02-15

    Despite the tremendous progress made toward establishing PLS as a new paradigm to guarantee security of communication systems at the physical layerthere is a common belief among researchers and industrials that there are many practical challenges that prevent PLS from flourishing at the industrial scale. Most secure message transmission constructions available to date are tied to strong assumptions on CSI, consider simple channel models and undermine eavesdropping capabilities; thus compromising their practical interest to a big extent. Perhaps arguably, the most likely reasonable way to leverage PLS potential in securing modern wireless communication systems is via secret-key agreement. In the latter setting, the legitimate parties try to agree on a key exploiting availability of a public channel with high capacity which is also accessible to the eavesdropper. Once a key is shared by the legitimate parties, they may use it in a one-time pad encryption, for instance. In this article, we investigate two performance limits of secret-key agreement communications; namely, the secret-key diversity-multiplexing trade-off and the effect of transmit correlation on the secretkey capacity. We show via examples how secretkey agreement offers more flexibility than secure message transmissions. Finally, we explore a few challenges of secret-key agreement concept and propose a few guidelines to overturn them.

  19. 17 CFR 160.5 - Annual privacy notice to customers required.

    Science.gov (United States)

    2010-04-01

    ... customers required. 160.5 Section 160.5 Commodity and Securities Exchanges COMMODITY FUTURES TRADING... notice to customers required. (a)(1) General rule. You must provide a clear and conspicuous notice to customers that accurately reflects your privacy policies and practices not less than annually during the...

  20. Technical Analysis in Forex : A Strategy for Individual Trader in Intra-Day Trading

    OpenAIRE

    Linden, Miikka

    2009-01-01

    The goal of the thesis was to create a simple and profitable strategy for Foreign Exchange Market (forex) currency trading. Forex is an interesting international market, which is becom-ing globally more and more popular. The author has a strong interest in forex and he had no-ticed how many trading strategies are very complicated and difficult to use. The meaning was to study what kind of simple trading strategy would be profitable in forex. The target of the study was intra-day traders, who ...

  1. 76 FR 61342 - Foreign-Trade Zone 72 Temporary/Interim Manufacturing Authority Brevini Wind USA, Inc., (Wind...

    Science.gov (United States)

    2011-10-04

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board [Docket T-3-2011] Foreign-Trade Zone 72 Temporary/Interim Manufacturing Authority Brevini Wind USA, Inc., (Wind Turbine Gear Boxes); Notice of Approval On... manufacturing (T/IM) authority, on behalf of Brevini Wind USA, Inc., to manufacture wind turbine gear boxes...

  2. 76 FR 28055 - Notice of Meeting

    Science.gov (United States)

    2011-05-13

    ... confidential trade secrets or commercial property such as patentable material, and personal information... below, with attendance limited to space available. Individuals who plan to attend and need special... Federal Domestic Assistance Program Nos. 93.14, Intramural Research Training Award; 93.22, Clinical...

  3. African agricultural trade

    DEFF Research Database (Denmark)

    Jensen, Hans Grinsted; Sandrey, Ron

    2015-01-01

    This article starts with a profile of African agricultural trade. Using the pre-release version 9.2 of the GTAP database, we then show that the results for tariff elimination on intra-African trade are promising, but these tariff barriers are not as significant as the various trade-related barriers...... outside of tariffs. Impressive results were forecast by simulating both a 50% reduction in what can be considered traditional non-tariff barriers and a modest 20% reduction in the costs associated with transit time delays at customs, terminals and internal land transportation. Gains from tariff...... elimination, non-tariff barrier reductions and time in transit cost reductions are likely to be cumulative and would generate very large gains to Africa. The policy implications are clear: while cooperation will enhance the gains, much of the benefits will result from unilateral actions and regional...

  4. The Algerian Foreign Trade between the Multilateral Trading System and the Regionalism

    Directory of Open Access Journals (Sweden)

    Khayreddine Belaaze

    2014-04-01

    Full Text Available This contribution aims at highlighting a major challenge facing global trade and trade in developing countries. Indeed, regional and preferential trade agreements are now more than ever inconsistent and incoherent and one of the principles of the World Trade Organization, the clause of the most favored nation requiring eliminated all forms of discrimination between trading parties, but what we see in regional trade agreements that the preferential tariffs based on a principle of discrimination. All regional trade agreements granting preferential tariffs between member countries, these preferences do not include the remains of non-member countries (rest of world. On the other hand, preferential tariffs are lower than MFN rates. Meanwhile, the number of regional agreements has doubled since 1995 date creation of the WTO, and Algeria like other developing countries considered one of countries which have not benefit a lot from this situation.

  5. Challenges to the Multilateral Trading System

    OpenAIRE

    Peter Sutherland

    2007-01-01

    Ever since the GATT was established in 1948, the growth in international trade and economic growth has been remarkable. The traditional mercantilism of trade relations is less and less appropriate for the global economy. Bilateral trade deals make the business environment more complex and unpredictable. Preferential trading agreements erode the principle of non-discrimination. They distort trade away from the underlying comparative advantage; create rents which are appropriated by special pro...

  6. 40 CFR 350.5 - Assertion of claims of trade secrecy.

    Science.gov (United States)

    2010-07-01

    ... deleted, and the generic class or category of the chemical identity or identities inserted in its place... place of the specific chemical identity claimed as trade secret, the generic class or category of the... the specific chemical identity of an extremely hazardous substance under sections 303 (d)(2) and (d)(3...

  7. THE PLACE OF SWITZERLAND IN ROMANIA'S FOREIGN TRADE WITH EFTA DURING 2007-2016

    Directory of Open Access Journals (Sweden)

    ZAMFIR PAUL BOGDAN

    2017-06-01

    Full Text Available In this paper it is presented in a synthetic manner the overall evolution of bilateral trade between Romania and Switzerland in the current period of post-accession of our country to EU. Therefore, in order to be successed on this market - to achieve and maintain stable and long-term commercial relations partners, romanian exporters should pay very attention strict implementation of contractual terms, equality rules, conditions and delivery terms and possibly to inform previously on local prices of competing firms. Also it is important to emphasize that the current EU's legal framework regarding trade relations influenced positively the entire climate of bilateral trade between Romanian and Swiss economic agents. At the same time, the bilateral agreements are also applied by Romania in virtue of its quality as member state of EU that automatically adopted and implemented EU legislation, the international treaties and agreements with third countries. Thus, it is noticeable that in post-accession period to the EU, our country in the field of foreign trade with Switzerland applies the legal framework of EU that has as main effect the development of trade conducted between Romanian and Swiss companies. Also, regarding Romania's foreign trade with EFTA states in the current period of post accession to EU it can be noticed a major improvement, due to the three countries of The European Free Trade Association (EFTA except Switzerland is subject to the European Economic Area (EEA Agreement. In this context the elimination of customs duties in trade between our country and EFTA states leads undoubtedly to entry on Romanian market of products with high quality designed to meet the requirements of domestic demand.

  8. Immunomodulatory factors in cervicovaginal secretions from pregnant and non-pregnant women: A cross-sectional study

    Directory of Open Access Journals (Sweden)

    Stek Alice

    2011-09-01

    Full Text Available Abstract Background Pregnant women are at an increased risk for HIV infection due to unknown biological causes. Given the strong effect of sex-hormones on the expression of immunomuodulatory factors, the central role of mucosal immunity in HIV pathogenesis and the lack of previous studies, we here tested for differences in immunomuodulatory factors in cervico-vaginal secretions between pregnant and non-pregnant women. Methods We compared concentrations of 39 immunomodulatory factors in cervicovaginal lavages (CVL from 21 pregnant women to those of 24 non-pregnant healthy women from the US. We used Bonferroni correction to correct for multiple testing and linear regression modeling to adjust for possible confounding by plasma cytokine concentration, cervical ectopy, total protein concentration, and other possible confounders. Cervical ectopy was determined by planimetry. Concentration of immunomodulatory factors were measured by a multiplex assay, protein concentration by the Bradford Method. Results Twenty six (66% of the 39 measured immunomodulatory factors were detectable in at least half of the CVL samples included in the study. Pregnant women had threefold lower CVL concentration of CCL22 (geometric mean: 29.6 pg/ml versus 89.7 pg/ml, p = 0.0011 than non-pregnant women. CVL CCL22 concentration additionally correlated negatively with gestational age (Spearman correlation coefficient [RS]: -0.49, p = 0.0006. These associations remained significant when corrected for multiple testing. CCL22 concentration in CVL was positively correlated with age and negatively correlated with time since last coitus and the size of cervical ectopy. However, none of these associations could explain the difference of CCL22 concentration between pregnant and non-pregnant women in this study, which remained significant in adjusted analysis. Conclusions In this study population, pregnancy is associated with reduced concentrations of CCL22 in cervicovaginal secretions

  9. 75 FR 39971 - In the Matter of Certain Electronic Imaging Devices; Notice of Investigation

    Science.gov (United States)

    2010-07-13

    ... INTERNATIONAL TRADE COMMISSION [Inv. No. 337-TA-726] In the Matter of Certain Electronic Imaging Devices; Notice of Investigation AGENCY: U.S. International Trade Commission. ACTION: Institution of....S. International Trade Commission on May 13, 2010, under section 337 of the Tariff Act of 1930, as...

  10. 78 FR 49789 - Request for Comments and Notice of Public Hearing Concerning Russia's Implementation of Its WTO...

    Science.gov (United States)

    2013-08-15

    ... its obligations as a Member of the World Trade Organization (WTO). SUMMARY: The interagency Trade... the WTO are contained in the Marrakesh Agreement Establishing the World Trade Organization (WTO... OFFICE OF THE UNITED STATES TRADE REPRESENTATIVE Request for Comments and Notice of Public Hearing...

  11. Rotavirus NSP4 is secreted from infected cells as an oligomeric lipoprotein and binds to glycosaminoglycans on the surface of non-infected cells

    Directory of Open Access Journals (Sweden)

    Didsbury Alicia

    2011-12-01

    Full Text Available Abstract Background Nonstructural glycoprotein 4 (NSP4 encoded by rotavirus is the only viral protein currently believed to function as an enterotoxin. NSP4 is synthesized as an intracellular transmembrane glycoprotein and as such is essential for virus assembly. Infection of polarized Caco-2 cells with rotavirus also results in the secretion of glycosylated NSP4 apparently in a soluble form despite retention of its transmembrane domain. We have examined the structure, solubility and cell-binding properties of this secreted form of NSP4 to further understand the biochemical basis for its enterotoxic function. We show here that NSP4 is secreted as discrete detergent-sensitive oligomers in a complex with phospholipids and demonstrate that this secreted form of NSP4 can bind to glycosaminoglycans present on the surface of a range of different cell types. Methods NSP4 was purified from the medium of infected cells after ultracentrifugation and ultrafiltration by successive lectin-affinity and ion exchange chromatography. Oligomerisation of NSP4 was examined by density gradient centrifugation and chemical crosslinking and the lipid content was assessed by analytical thin layer chromatography and flame ionization detection. Binding of NSP4 to various cell lines was measured using a flow cytometric-based assay. Results Secreted NSP4 formed oligomers that contained phospholipid but dissociated to a dimeric species in the presence of non-ionic detergent. The purified glycoprotein binds to the surface of various non-infected cells of distinct lineage. Binding of NSP4 to HT-29, a cell line of intestinal origin, is saturable and independent of divalent cations. Complementary biochemical approaches reveal that NSP4 binds to sulfated glycosaminoglycans on the plasma membrane. Conclusion Our study is the first to analyze an authentic (i.e. non-recombinant form of NSP4 that is secreted from virus-infected cells. Despite retention of the transmembrane domain

  12. 19 CFR 210.78 - Notice of enforcement action to Government agencies.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Notice of enforcement action to Government agencies. 210.78 Section 210.78 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE ADJUDICATION AND ENFORCEMENT Enforcement Procedures and Advisory...

  13. Colonic mucin secretion related to non-contractile motility in the dog

    International Nuclear Information System (INIS)

    Skioedebrand, C.G.; Margulis, A.R.; Hattner, R.S.; Hartmeyer, J.; Stoughton, J.A.

    1981-01-01

    In 8 dogs a colonic pouch with fistula was surgically created. Mucin secretion was measured by washing mucus out of the pouch and then, after a number of chemical steps, by determining the turbidity with spectrophotometry. The movement of tantalum particles insufflated into the canine rectum during periods of absence of contractions was correlated with mucus secretion in the pouch. Correlations were made after parenteral injection of secretin which increased movement of tantalum particles and production of mucin, and after injection of glucagon, which stopped movement of the particles and decreased mucin secretion in the pouch. Movement of tantalum was also observed when the particles were insufflated into the canine rectum on top of an applied layer of water-soluble jelly. (Auth.)

  14. Gamma-knife surgery for secreting pituitary adenomas

    International Nuclear Information System (INIS)

    Morange-Ramos, I.; Andrieu, J.M.; Jaquet, P.; Regis, J.; Dufour, H.; Grisoli, F.; Peragut, J.C.

    1998-01-01

    We report our preliminary results concerning 25 patients with secreting pituitary adenomas treated with stereotactic radiosurgery after partial transsphenoidal surgery and followed over a 6-36 month-period. Among the 15 acromegalic patients, a decrease of 65% in mean GH levels was achieved after 6 months and of 77% at 12 months after radiosurgery. Presently, only 3 patients (20%) are considered as in remission (mean GH and IGF1 level into the normal range). A decrease of 46% and 64% was observed at 6 and 12 months after radiosurgery in 4 patients with prolactinomas although no normalization of PRL levels occurred. Presently, 3/4 patients have individual PRL levels slightly above the normal range. A normalization of Urinary Free Cortisol (UFC) was noticed in 4/6 (66%) patients with Cushing's disease within 6-12 months. No pituitary deficiency was noticed in this series with the exception of 4/25 patients (16%) who received subtotal or total pituitary irradiation for post-operative remnants of secreting adenomas poorly defined on MRI. One woman, who had undergone previously a conventional irradiation and presenting with a cavernous sinus adenoma reaching the optic nerve, developed an optic neuropathy. A second woman, with a cavernous sinus remnant, presented a cranial nerve palsy (VI) after the irradiation. We can conclude that radiosurgery using the Cobalt-60 Gamma-unit is, at least, as effective as conventional radiotherapy in the control of pituitary hormone hypersecretion from postoperative adenomas remnants with less adverse effects. (author)

  15. Studies on insulin secretion and insulin resistance in non-insulin-dependent diabetes in young Indians

    International Nuclear Information System (INIS)

    Naidoo, C.

    1986-01-01

    Patients with Non-insulin-dependent diabetes mellitus (NIDDM) have defects in insulin secretion and insulin action. In the discrete genetic syndrome of NIDDY (non-insulin-dependent diabetes in the young), the situation is less clear and these aspects is the subject of this thesis. This study included Indian pasients with three generation transmission of NIDDM via one parent. The insulin and C-peptide responses to oral and intravenous glucose in patients with NIDDY were studied. The insulin and glucose responses to non-glucose secretogogues glucagon, tolbutamide and arginine, in NIDDY were also investigated. The following aspects with regard to insulin resistance in NIDDY were examined: glucose and free fatty acid response to intravenous insulin administration, insulin binding to circulating erythrocytes and monocytes, 125 I-insulin binding to the solubilized erythrocyte membrane receptor and 125 I-insulin binding to fibroblasts in culture

  16. Studies on insulin secretion and insulin resistance in non-insulin-dependent diabetes in young Indians

    Energy Technology Data Exchange (ETDEWEB)

    Naidoo, C

    1986-01-01

    Patients with Non-insulin-dependent diabetes mellitus (NIDDM) have defects in insulin secretion and insulin action. In the discrete genetic syndrome of NIDDY (non-insulin-dependent diabetes in the young), the situation is less clear and these aspects is the subject of this thesis. This study included Indian pasients with three generation transmission of NIDDM via one parent. The insulin and C-peptide responses to oral and intravenous glucose in patients with NIDDY were studied. The insulin and glucose responses to non-glucose secretogogues glucagon, tolbutamide and arginine, in NIDDY were also investigated. The following aspects with regard to insulin resistance in NIDDY were examined: glucose and free fatty acid response to intravenous insulin administration, insulin binding to circulating erythrocytes and monocytes, /sup 125/I-insulin binding to the solubilized erythrocyte membrane receptor and /sup 125/I-insulin binding to fibroblasts in culture.

  17. International greenhouse gas emissions trading. Who should be held liable for the non-compliance by sellers?

    International Nuclear Information System (INIS)

    Zhang, Zhong Xiang

    1999-01-01

    Article 17 of the Kyoto Protocol authorizes emissions trading, but the rules governing emissions trading have been deferred to subsequent conferences. In designing and implementing an international greenhouse gas (GHG) emissions trading scheme, assigning liability has been considered to be one of the most challenging issues. This article discusses a variety of the rules for accountability under international GHG emissions trading. It indicates that a 'buyer beware' liability is effective only to the extent that it puts additional pressure on sellers to comply with their commitments because after all sellers exercise great, if not complete, control over whether or not they comply with their commitments. Because putting such a pressure on sellers to develop effective compliance systems is not without costs to buyers, a 'buyer beware' liability should thus be imposed only in the case where non-compliance of sellers is virtually certain to occur. Moreover, in determining the optimal combination of these not-mutually-exclusive rules for accountability that are discussed in the article, the marginal benefits of adding one rule needs to be weighted against the increased costs of doing so. 12 refs

  18. 76 FR 81984 - Bureau of International Labor Affairs; Office of Trade and Labor Affairs; Bahrain-United States...

    Science.gov (United States)

    2011-12-29

    ... and Labor Affairs; Bahrain--United States Free Trade Agreement; Notice of Extension of the Period of...) of the Bahrain--United States Free Trade Agreement (FTA). The submission was received on April 21... of Inquiry and the proposal of the Government of Bahrain to the Governing Body of the International...

  19. Pituitary-hormone secretion by thyrotropinomas.

    Science.gov (United States)

    Roelfsema, Ferdinand; Kok, Simon; Kok, Petra; Pereira, Alberto M; Biermasz, Nienke R; Smit, Jan W; Frolich, Marijke; Keenan, Daniel M; Veldhuis, Johannes D; Romijn, Johannes A

    2009-01-01

    Hormone secretion by somatotropinomas, corticotropinomas and prolactinomas exhibits increased pulse frequency, basal and pulsatile secretion, accompanied by greater disorderliness. Increased concentrations of growth hormone (GH) or prolactin (PRL) are observed in about 30% of thyrotropinomas leading to acromegaly or disturbed sexual functions beyond thyrotropin (TSH)-induced hyperthyroidism. Regulation of non-TSH pituitary hormones in this context is not well understood. We there therefore evaluated TSH, GH and PRL secretion in 6 patients with up-to-date analytical and mathematical tools by 24-h blood sampling at 10-min intervals in a clinical research laboratory. The profiles were analyzed with a new deconvolution method, approximate entropy, cross-approximate entropy, cross-correlation and cosinor regression. TSH burst frequency and basal and pulsatile secretion were increased in patients compared with controls. TSH secretion patterns in patients were more irregular, but the diurnal rhythm was preserved at a higher mean with a 2.5 h phase delay. Although only one patient had clinical acromegaly, GH secretion and IGF-I levels were increased in two other patients and all three had a significant cross-correlation between the GH and TSH. PRL secretion was increased in one patient, but all patients had a significant cross-correlation with TSH and showed decreased PRL regularity. Cross-ApEn synchrony between TSH and GH did not differ between patients and controls, but TSH and PRL synchrony was reduced in patients. We conclude that TSH secretion by thyrotropinomas shares many characteristics of other pituitary hormone-secreting adenomas. In addition, abnormalities in GH and PRL secretion exist ranging from decreased (joint) regularity to overt hypersecretion, although not always clinically obvious, suggesting tumoral transformation of thyrotrope lineage cells.

  20. 75 FR 4449 - Requested Administrative Waiver of the Coastwise Trade Laws; Correction

    Science.gov (United States)

    2010-01-27

    ... DEPARTMENT OF TRANSPORTATION Maritime Administration [Docket No. MARAD-2010-0001] Requested Administrative Waiver of the Coastwise Trade Laws; Correction AGENCY: Maritime Administration, Department of Transportation. ACTION: Notice; correction. SUMMARY: On January 15, 2010, the Maritime Administration published...

  1. Relative intensity of bilateral trade flows, regional integration, and trade performance: the case of Brazil, 1984-1998

    Directory of Open Access Journals (Sweden)

    Silva Valquiria da

    2003-01-01

    Full Text Available The objective of this research is to identify the component of trade that results specifically from bilateral relations and evaluate how the creation of trading blocs affects trade relations between countries. The trirapport coefficient of the relative intensity of bilateral agricultural sector trade flows between Brazil and other countries from 1984 and 1998 is used in the evaluation. In general, the results show that relative trade intensity between Brazil and its non-MERCOSUL trade partners fell after their entry into regional trade agreements (extra-bloc effect. The intra-bloc effect (trade expansion is reflected by changes in trade intensity between Brazil and the other MERCOSUL members and changes in trade intensity between NAFTA members Mexico, Canada, and the United States.

  2. 15 CFR 325.6 - Publishing notices in the Federal Register.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Publishing notices in the Federal... CERTIFICATES OF REVIEW § 325.6 Publishing notices in the Federal Register. (a) Within ten days after an... conduct for which certification is sought. If the Secretary does not intend to publish the summary...

  3. Is the Classification of International Trade in Horizontal and Vertical Intra-Industry Trade Usable?

    DEFF Research Database (Denmark)

    Nielsen, Jørgen Ulff-Møller; Lüthje, Teit

    2001-01-01

    with vertical intra-industry trade (between Germany and France) making up 50-60%. The high level of vertical intra-industry trade probably covers up many products shifting between e.g. vertical and horizontal intra-industry. The statement from the literature that the European integration process involves heavy......Abstract On the basis of OECD trade statistics at SITC 5 digit level for the period 1961-1999 we show the classification of international trade in (a) inter-industry trade and (b) horizontal intra-industry and (c) vertical intra-industry trade used in the empirical trade literature to be non stable...... at the individual product level. This indicates that this type of statistical classification based on unit-values is probably not very useful. On the other hand, we also show in accordance with the literature that the aggregate distribution of trade into the three categories apparently is rather stable...

  4. Calculation of frequency of optimal inspection in non-notice inspection game

    International Nuclear Information System (INIS)

    Kumakura, Shinichi; Gotoh, Yoshiki; Kikuchi, Masahiro

    2011-01-01

    We consider a non-notice inspection game between an inspection party, who verifies absence of diversion of nuclear materials and misuse of nuclear facility, and a facility operator, who tries them in a nuclear facility. In the game, the payoff for each player, inspection party and facility operator, is composed of various elements (parameters) such as facility type, a type of nuclear material, number of inspection and others. Their payoffs consist of profits and costs (minus profit). Because of random nature by non-notice inspection, its deterrence effect and inspection number could have the potential to affect their payoffs. In this paper, their payoffs taking into consideration of the inspection environment above are represented as a function of inspection number. Then, the optimal number is calculated from a condition on their payoffs for number of inspection. Comparable statics analysis is performed in order to observe the change of inspection number which is equilibrium point by changing these parameters including deterrence effect, because the number derived depends on each parameter within the inspection environment. Based on the analysis results, necessary conditions to reduce the inspection number keeping inspection effect are pointed out. (author)

  5. Effect of non-tariff barriers on secondary processed wood product trade: New Zealand exports to the United States, China and Japan

    Science.gov (United States)

    James A. Turner; Joseph Buongiorno; Shushuai Zhu; Frances Maplesden

    2008-01-01

    Secondary processed wood products - builder's carpentry and joinery, moldings and millwork, wooden furniture, and prefabricated buildings - have grown significantly in importance in the global trade of wood products. At the same time there has been increased use of non-tariff barriers to restrict their trade.  These barriers could have an important impact on the...

  6. 78 FR 66894 - Notice of Extension of the Deadline for Determining the Adequacy of the Antidumping Duty and...

    Science.gov (United States)

    2013-11-07

    ... DEPARTMENT OF COMMERCE International Trade Administration [A-570-998, C-570-999] Notice of..., formerly Import Administration, International Trade Administration, Department of Commerce DATES: Effective... Operations, Office V, Enforcement and Compliance, International Trade Administration, Department of Commerce...

  7. 78 FR 54664 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-09-05

    ...., as amended. The grant applications and the discussions could disclose confidential trade secrets or..., Functional and Cognitive Neuroscience Integrated Review Group; Sensorimotor Integration Study Section. Date...

  8. Pancreatic bicarbonate secretion involves two proton pumps.

    Science.gov (United States)

    Novak, Ivana; Wang, Jing; Henriksen, Katrine L; Haanes, Kristian A; Krabbe, Simon; Nitschke, Roland; Hede, Susanne E

    2011-01-07

    Pancreas secretes fluid rich in digestive enzymes and bicarbonate. The alkaline secretion is important in buffering of acid chyme entering duodenum and for activation of enzymes. This secretion is formed in pancreatic ducts, and studies to date show that plasma membranes of duct epithelium express H(+)/HCO(3)(-) transporters, which depend on gradients created by the Na(+)/K(+)-ATPase. However, the model cannot fully account for high-bicarbonate concentrations, and other active transporters, i.e. pumps, have not been explored. Here we show that pancreatic ducts express functional gastric and non-gastric H(+)-K(+)-ATPases. We measured intracellular pH and secretion in small ducts isolated from rat pancreas and showed their sensitivity to H(+)-K(+) pump inhibitors and ion substitutions. Gastric and non-gastric H(+)-K(+) pumps were demonstrated on RNA and protein levels, and pumps were localized to the plasma membranes of pancreatic ducts. Quantitative analysis of H(+)/HCO(3)(-) and fluid transport shows that the H(+)-K(+) pumps can contribute to pancreatic secretion in several species. Our results call for revision of the bicarbonate transport physiology in pancreas, and most likely other epithelia. Furthermore, because pancreatic ducts play a central role in several pancreatic diseases, it is of high relevance to understand the role of H(+)-K(+) pumps in pathophysiology.

  9. Cardiovascular events and mortality in patients with adrenal incidentalomas that are either non-secreting or associated with intermediate phenotype or subclinical Cushing's syndrome: a 15-year retrospective study.

    Science.gov (United States)

    Di Dalmazi, Guido; Vicennati, Valentina; Garelli, Silvia; Casadio, Elena; Rinaldi, Eleonora; Giampalma, Emanuela; Mosconi, Cristina; Golfieri, Rita; Paccapelo, Alexandro; Pagotto, Uberto; Pasquali, Renato

    2014-05-01

    Incidental discovery of adrenal masses has increased over the past few years. Mild alterations in cortisol secretion without clinical signs of overt hypercortisolism (subclinical Cushing's syndrome) are a common finding in patients with these tumours. Although metabolic alterations and increased cardiovascular risk have been noted in patients with subclinical Cushing's syndrome, incidence of cardiovascular events and mortality in the long term have not been assessed. We aimed to ascertain the frequency of new cardiovascular events and mortality in patients with non-secreting adrenal incidentalomas, tumours of intermediate phenotype, or those causing subclinical Cushing's syndrome. From January, 1995, to September, 2010, consecutive outpatients with adrenal incidentalomas who were referred to the endocrinology unit of S Orsola-Malpighi Hospital, Bologna, Italy, were enrolled into our study. Individuals were assessed every 18-30 months for the first 5 years (mean follow-up 7·5 [SD 3·2] years, range 26 months to 15 years). Cortisol concentrations after the 1 mg dexamethasone suppression test (DST) were used to define non-secreting (+50 nmol/L) and intermediate phenotype (50-138 nmol/L) adrenal incidentalomas and subclinical Cushing's syndrome (+138 nmol/L). At the end of follow-up, patients were reclassified as having either unchanged or worsened secreting patterns from baseline. 198 outpatients were assessed; at the end of follow-up, 114 patients had stable non-secreting adrenal incidentalomas, 61 had either a stable intermediate phenotype or subclinical Cushing's syndrome, and 23 had a pattern of secretion that had worsened. By comparison with patients with stable non-secreting adrenal incidentalomas, the incidence of cardiovascular events was higher in individuals with a stable intermediate phenotype or subclinical Cushing's syndrome (6·7% vs 16·7%; p=0·04) and in those with worsened secreting patterns (6·7% vs 28·4%; p=0·02). Cardiovascular events were

  10. A catalogue of human secreted proteins and its implications

    Directory of Open Access Journals (Sweden)

    Shivakumar Keerthikumar

    2016-11-01

    Full Text Available Under both normal and pathological conditions, cells secrete variety of proteins through classical and non-classical secretory pathways into the extracellular space. Majority of these proteins represent pathophysiology of the cell from which it is secreted. Recently, though more than 92% of the protein coding genes has been mapped by human proteome map project, but number of those proteins that constitutes secretome of the cell still remains elusive. Secreted proteins or the secretome can be accessible in bodily fluids and hence are considered as potential biomarkers to discriminate between healthy and diseased individuals. In order to facilitate the biomarker discovery and to further aid clinicians and scientists working in these arenas, we have compiled and catalogued secreted proteins from the human proteome using integrated bioinformatics approach. In this study, nearly 14% of the human proteome is likely to be secreted through classical and non-classical secretory pathways. Out of which, ~38% of these secreted proteins were found in extracellular vesicles including exosomes and shedding microvesicles. Among these secreted proteins, 94% were detected in human bodily fluids including blood, plasma, serum, saliva, semen, tear and urine. We anticipate that this high confidence list of secreted proteins could serve as a compendium of candidate biomarkers. In addition, the catalogue may provide functional insights in understanding the molecular mechanisms involved in various physiological and pathophysiological conditions of the cell.

  11. Gravity Models of Trade-Based Money Laundering

    OpenAIRE

    Ferwerda, Joras; Kattenberg, Marc; Chang, Han-Hsin; Unger, Brigitte; Groot, Loek; Bikker, Jaap

    2011-01-01

    Several attempts have been made in the economics literature to measure money laundering. However, the adequacy of these models is difficult to assess, as money laundering takes place secretly and, hence, goes unobserved. An exception is tradebased money laundering (TBML), a special form of trade abuse that has been discovered only recently. TBML refers to criminal proceeds that are transferred around the world using fake invoices that under- or overvalue imports and exports. This article is a...

  12. 19 CFR 210.14 - Amendments to pleadings and notice; supplemental submissions; counterclaims.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Amendments to pleadings and notice; supplemental submissions; counterclaims. 210.14 Section 210.14 Customs Duties UNITED STATES INTERNATIONAL TRADE COMMISSION INVESTIGATIONS OF UNFAIR PRACTICES IN IMPORT TRADE ADJUDICATION AND ENFORCEMENT Pleadings § 210.14 Amendments to...

  13. 76 FR 60082 - In the Matter of Certain Light-Emitting Diodes and Products Containing Same; Notice of Commission...

    Science.gov (United States)

    2011-09-28

    ... Corporate Name Change AGENCY: U.S. International Trade Commission. ACTION: Notice. SUMMARY: Notice is hereby... motion to amend the complaint and notice of investigation to reflect a corporate name change in the above... moved to amend the complaint and notice of investigation to reflect a recent change of its corporate...

  14. The Regulation of Nuclear Trade: Non-Proliferation-Supply-safety

    International Nuclear Information System (INIS)

    1988-01-01

    Volume II of the study on the regulation of nuclear trade deals with the national legislation of OECD countries with significant nuclear programmes and regulations in that field and, in essence, covers two aspects. The first concerns political and administrative controls over imports and exports of sensitive products, namely fissile materials and large nuclear equipment as well as technology transfers. In most cases, this description of the provisions applicable is completed with the list of nuclear items whose export is restricted. The second aspect concerns the licensing system governing trade in as well as the import and export of nuclear material to protect users and the public against the hazards created by its radioactive properties. This volume also contains information on regulations concerning physical protection, industrial property and transport, as well as on multilateral and bilateral agreements involving nuclear trade. (NEA) [fr

  15. Energy use, emissions, economic growth and trade: A Granger non-causality evidence for Malaysia

    OpenAIRE

    Ismail, Mohd Adib; Mawar, Murni Yunus

    2012-01-01

    This paper investigates the relationship among energy, emissions and economic growth in Malaysia with the presence of trade activities. We employ Johansen’s (1995) approach to investigate the relationship. Using annual data from 1971 to 2007, the empirical results shows that there are long-run causalities among energy, emission and economic growth, and among energy, emissions, export and capital, while the short-run Granger non-causality test shows that there are unidirectional causalities ru...

  16. Unilateral Measures addressing Non-Trade Concerns. A Study on WTO Consistency, Relevance of other International Agreements, Economic Effectiveness and Impact on Developing Countries of Measures concerning Non-Product-Related Processes and Production Methods

    International Nuclear Information System (INIS)

    Van den Bossche, P.; Schrijver, N.; Faber, G.

    2007-01-01

    Over the last two years, the debate in the Netherlands on trade measures addressing non-trade concerns has focused on two important and politically sensitive issues, namely: (1) the sustainability of the large-scale production of biomass as an alternative source of energy; and (2) the production of livestock products in a manner that is consistent with animal welfare requirements. In February 2007 a report was issued on the 'Toetsingskader voor Duurzame Biomassa', the so-called Cramer Report. This report discusses the risks associated with large-scale biomass production and establishes a list of criteria for the sustainable production of biomass. These criteria reflect a broad range of non-trade concerns, including environmental protection, global warming, food security, biodiversity, economic prosperity and social welfare. The report recognizes that the implementation of the criteria (including the establishment of a certification system) will require careful consideration of the obligations of the Netherlands under EU and WTO law. Governments called upon to address non-trade concerns may do so by using different types of measures. Prominent among these are measures concerning processes and production methods of products. In the present study, these issues are examined primarily with regard to existing, proposed or still purely hypothetical measures for implementing the Cramer criteria for the sustainable production of biomass. Several other, non-energy-related issues are discussed in this report

  17. The signaling cascades of Ganoderma lucidum extracts in stimulating non-amyloidogenic protein secretion in human neuroblastoma SH-SY5Y cell lines.

    Science.gov (United States)

    Pinweha, Sirinthorn; Wanikiat, Payong; Sanvarinda, Yupin; Supavilai, Porntip

    2008-12-19

    Ganoderma lucidum (GL) is a medicinal mushroom that possesses various pharmacological properties which are also documented in the ancient reports where GL is praised for its effects on the promotion of health and longevity. In this study, we have investigated the effect of GL mycelia extracts on the non-amyloidogenic protein secretion (sAPPalpha) and the amyloid precursor protein (APP) expression in SH-SY5Y neuroblastoma cells. In order to characterize the signaling pathway which mediates GL-enhanced sAPPalpha secretion, we used inhibitors of nerve growth factor (NGF) signaling pathways, phosphatidylinositol 3 kinase (PI3K), phospholipase Cgamma1 (PLCgamma1), protein kinase C (PKC) and extracellular signal-regulated kinase (ERK1/2), to block GL-mediated sAPPalpha secretion as well as ERK1/2 and PKC activation by using Western blot analysis. Our results provided for the first time evidence that GL mycelia extracts increased APP expression and promoted sAPPalpha secretion. In addition, GL extracts activated ERK1/2 and PKC phosphorylation. The complex signaling cascades of PI3K and ERK may be responsible for GL-mediated sAPPalpha secretion.

  18. 75 FR 28651 - In the Matter of Certain Electronic Paper Towel Dispensing Devices and Components Thereof; Notice...

    Science.gov (United States)

    2010-05-21

    ... INTERNATIONAL TRADE COMMISSION [Inv. No. 337-TA-718] In the Matter of Certain Electronic Paper Towel Dispensing Devices and Components Thereof; Notice of Investigation AGENCY: International Trade... that a complaint was filed with the U.S. International Trade Commission on April 19, 2010, under...

  19. Herbivore Oral Secreted Bacteria Trigger Distinct Defense Responses in Preferred and Non-Preferred Host Plants.

    Science.gov (United States)

    Wang, Jie; Chung, Seung Ho; Peiffer, Michelle; Rosa, Cristina; Hoover, Kelli; Zeng, Rensen; Felton, Gary W

    2016-06-01

    Insect symbiotic bacteria affect host physiology and mediate plant-insect interactions, yet there are few clear examples of symbiotic bacteria regulating defense responses in different host plants. We hypothesized that plants would induce distinct defense responses to herbivore- associated bacteria. We evaluated whether preferred hosts (horsenettle) or non-preferred hosts (tomato) respond similarly to oral secretions (OS) from the false potato beetle (FPB, Leptinotarsa juncta), and whether the induced defense triggered by OS was due to the presence of symbiotic bacteria in OS. Both horsenettle and tomato damaged by antibiotic (AB) treated larvae showed higher polyphenol oxidase (PPO) activity than those damaged by non-AB treated larvae. In addition, application of OS from AB treated larvae induced higher PPO activity compared with OS from non-AB treated larvae or water treatment. False potato beetles harbor bacteria that may provide abundant cues that can be recognized by plants and thus mediate corresponding defense responses. Among all tested bacterial isolates, the genera Pantoea, Acinetobacter, Enterobacter, and Serratia were found to suppress PPO activity in tomato, while only Pantoea sp. among these four isolates was observed to suppress PPO activity in horsenettle. The distinct PPO suppression caused by symbiotic bacteria in different plants was similar to the pattern of induced defense-related gene expression. Pantoea inoculated FPB suppressed JA-responsive genes and triggered a SA-responsive gene in both tomato and horsenettle. However, Enterobacter inoculated FPB eliminated JA-regulated gene expression and elevated SA-regulated gene expression in tomato, but did not show evident effects on the expression levels of horsenettle defense-related genes. These results indicate that suppression of plant defenses by the bacteria found in the oral secretions of herbivores may be a more widespread phenomenon than previously indicated.

  20. How to Recover From the Great Recession: The Case of a Two-Sector Small Open Economy with Traded and Non-Traded Capital

    Directory of Open Access Journals (Sweden)

    Jong-Kyou Jeon

    2013-06-01

    Full Text Available Since the global financial crisis in 2008, the world economy has been suffering from the Great Recession characterized by high and persistent unemployment as well as drastic fall in asset prices. Real business cycle theory or new-Keynesian economics which has been the dominant paradigm in macroeconomics for the last four decades is unable to explain the high and persistent unemployment during the Great Recession. This implies that the economics of Keynes should be taken seriously again as a tool to explain the Great Recession. Farmer (2012 proposes a new way of interpreting the economics of Keynes by providing it with a solid micro-foundation based on labor markets with search. According to Farmer (2012, aggregate economic activity independently depends on the long-term self-fulfilling expectations about the stock prices. As a consequence, the government or the central bank should implement a policy that influences the public's confidence about the stock market. For an open economy like the Korean economy, it is not only stock price but also the price of asset such as house that matters more for the aggregate economic activity. Households in the Korean economy hold more than 70 percent of their wealth in the form of real estate asset, especially housing asset. This makes the public's confidence about the future prices of houses even more important in explaining the business cycles of the Korean economy. Policymakers should implement policies to improve the confidence of households about the housing market to recover from the recession caused by a fall in house prices. Little theoretical work has been done in explaining fluctuations in the aggregate economic activity from the point of house prices. This paper develops a small open economy model with traded and non-traded capital based on Farmer (2012 and shows that the aggregate economic activity also independently depends on the households’ self-fulfilling expectations about the future prices

  1. Minimum quality standards and international trade

    DEFF Research Database (Denmark)

    Baltzer, Kenneth Thomas

    2011-01-01

    This paper investigates the impact of a non-discriminating minimum quality standard (MQS) on trade and welfare when the market is characterized by imperfect competition and asymmetric information. A simple partial equilibrium model of an international Cournot duopoly is presented in which a domes...... prefer different levels of regulation. As a result, international trade disputes are likely to arise even when regulation is non-discriminating....

  2. 77 FR 30584 - Notice of Termination of United States-Bolivia Bilateral Investment Treaty

    Science.gov (United States)

    2012-05-23

    ... of Termination of United States--Bolivia Bilateral Investment Treaty AGENCY: Department of State and Office of the United States Trade Representative. ACTION: Notice. SUMMARY: The Government of Bolivia has...-9580. SUPPLEMENTARY INFORMATION: Bolivia delivered notice on June 10, 2011, that it was terminating the...

  3. International trade. Multinational aspects.

    Science.gov (United States)

    Ozawa, Y

    2000-01-01

    Of numerous regional economic agreements, the European Union (EU), the North American Free Trade Agreement (NAFTA), South American Common Market (MERCOSUR), the Association of Southeast Asian Nations (ASEAN), the South Asian Association for Regional Cooperation (SAARC) and the Australia-New Zealand Closer Economic Relations Agreement are examples that are actively pursuing regional integration for freer trade of animals and animal products. The World Trade Organization (WTO) believes that regional and multinational integration initiatives are complements rather than alternatives in the pursuit of more open trade. In the efforts to harmonize SPS standards among multilateral trading nations, it is recommended that national requirements meet the standards developed by the OIE and the FAO/WHO Codex Alimentarius Commission as the minimum requirements rather than adopting the standards of the lowest common denominator. Regional grouping may hinder multilateral or bilateral trade between the countries of a group and those of the other groups. How to eliminate such non-tariff barriers as traditional trade custom remains to be examined. Ongoing activities of VICH (Harmonisation of Technical Requirements for Registration of Veterinary Medical Products) may pave the way for more open trade in pharmaceutical products between multilateral regional groups.

  4. 77 FR 52753 - U.S. Customs and Border Protection 2012 East Coast Trade Symposium: “Expanding 21st Century...

    Science.gov (United States)

    2012-08-30

    ... DEPARTMENT OF HOMELAND SECURITY U.S. Customs and Border Protection U.S. Customs and Border.... Customs and Border Protection, Department of Homeland Security (DHS). ACTION: Notice of trade symposium... Coast Trade Symposium will be held at the Renaissance DC Hotel, at 999 9th Street, NW., Washington, DC...

  5. 76 FR 73587 - Foreign-Trade Zone 183-Austin, Tx; Site Renumbering Notice

    Science.gov (United States)

    2011-11-29

    ... DEPARTMENT OF COMMERCE Foreign-Trade Zones Board Foreign-Trade Zone 183--Austin, Tx; Site... (Board Order 1366). FTZ 183 currently consists of 8 ``sites'' totaling some 2,818 acres in the Austin... Austin Enterprise Zone, located at Bolm Road and Gardner Road, Austin; Site 2 (50 acres)--Balcones...

  6. Medicinal use of secretions (“the frog vaccine” from the kambô frog (Phyllomedusa bicolor by non-indigenous peoples in Rondônia, Brazil

    Directory of Open Access Journals (Sweden)

    Paulo Sérgio Bernarde

    2009-09-01

    Full Text Available Amphibians have pharmaceutically active skin secretions that protect against infections and predation. Some indigenous people in southwestern Amazonia use these secretions from P. bicolor for medicinal purposes. While the use of these secretions by indigenous people is relatively well-known, the use by non-indigenous peoples is very poorly studied. Here we describe the use of the “frog vaccine” by non-indigenous populations in the Brazilian state of Rondônia. Thirty-one people who had received this “vaccine” were interviewed. The use of this vaccine is not typical or habitual in this region, and the person who administers the vaccine must travel from another part of Amazonia. Users of the vaccine come from middle and upper social classes with reasonable levels of education (primary, secondary and university. Approximately half the people vaccinated felt that their health had improved after vaccination and if need be, they would take the vaccination again. Most of the people do not know the frog species from which the secretions are taken. While the people who use this treatment believe that it is good for any infirmity, the medicinal properties, if any, of the “frog vaccine” are under study and are still unknown.

  7. 美國聯邦經濟間諜法之回顧與展望──兼論我國營業秘密法之刑罰化 Reviewing the U.S. Economic Espionage Act—With the Extending Comments on the 2013 Amendment of Taiwan’s Trade Secret Act

    Directory of Open Access Journals (Sweden)

    林志潔 Carol Chih-Chieh Lin

    2016-06-01

    Full Text Available 科技、經濟、國家安全,看似不相關的三個名詞,因營業秘密的存在而牢牢相扣。美國自1996 年起以聯邦層級的經濟間諜法來保護營業秘密,對於侵害營業秘密者課予刑事責任,並明確區分竊取營業秘密行為及經濟間諜行為,以嚇阻企業競爭對手竊取營業秘密,防止國家經濟、安全受到危害。然而,美國聯邦經濟間諜法施行至今已十九年,關於經濟間諜罪的案件,經法院判決確定有罪者卻為數不多,本文擬分析經濟間諜法實務上施行之困境,並提出改革建議。又,我國營業秘密法於2013 年增訂刑事規範第13 條之1至第13 條之4,主要參考自經濟間諜法,為分析比較,本文亦將一併檢討我國營業秘密法刑罰化後之問題。 “Technology, economic and national security,” these three words seem to be irrelevant on the surface; however, they are tightly bounded by the existence of the word—trade secret. The federal government of the U.S. passed the Economic Espionage Act in 1996 in an attempt to create a “comprehensive and systematic” approach to address trade secrecy misappropriation, drawing a clear line between economic espionage and theft of trade secrets through federal criminal justice system. It is established to prevent trade rivals from stealing other business’s most precious property—trade secret, and to protect the national economy, security from any harm. While the Economic Espionage Act has been implemented for 19 years, there are only few cases brought in a verdict of guilty, which seemingly contradicts to the legislative purposes. Therefore, this article aims to analyze the predicamentof the Act, and to give constructive propositions. Furthermore, the Trade Secret Act in Taiwan was revised in 2013. It mainly referred to the Economic Espionage, adding article 13-1 to 13-4. In order to compare and assay, this article will also probe into

  8. 76 FR 64417 - Self-Regulatory Organizations; International Securities Exchange, LLC; Notice of Filing and...

    Science.gov (United States)

    2011-10-18

    ... Organizations; International Securities Exchange, LLC; Notice of Filing and Immediate Effectiveness of Proposed Rule Change Relating to Competitive Market Maker Trading Rights October 12, 2011. Pursuant to Section...\\ notice is hereby given that on October 3, 2011, the International Securities Exchange, LLC (the...

  9. Pancreatic exocrine secretion in atomic bomb survivors

    International Nuclear Information System (INIS)

    Hiraoka, Masataka; Kawanishi, Masahiro; Ohtaki, Megu

    1989-01-01

    This study was designed to examine the effect of A-bombing on pancreatic exocrine secretion in 6 A-bomb survivors (an average age of 57 years) and the age- and sex-matched non-exposed 6 persons (an average age of 58 years). Six A-bomb survivors consisted of: three who had been directly exposed to A-bombing, one who had entered the city within 3 days after bombing, one who had worked in caring for A-bomb survivors, and one who had later entered the city. Caerulein-Secretin test revealed no significant difference in the total secretion of lipase, maximum bicarbonate, amylase output, or lipase output between the exposed and non-exposed groups. The concentration of lipase ten min after stimulation was significantly decreased in the exposed group than the control group. This suggests that radiation may be responsible for abnormality in the ability of pancreatic exocrine secretion. (N.K.)

  10. 78 FR 61424 - Self-Regulatory Organizations; National Securities Clearing Corporation; Notice of Filing of...

    Science.gov (United States)

    2013-10-03

    ... decommission the DTCC Trade Risk Pro service as more fully described below. II. Self-Regulatory Organization's... no Members that currently use Trade Risk Pro. (C) Self-Regulatory Organization's Statement on...-Regulatory Organizations; National Securities Clearing Corporation; Notice of Filing of Proposed Rule Change...

  11. Understanding the conventional arms trade

    Science.gov (United States)

    Stohl, Rachel

    2017-11-01

    The global conventional arms trade is worth tens of billions of dollars every year and is engaged in by every country in the world. Yet, it is often difficult to control the legal trade in conventional arms and there is a thriving illicit market, willing to arm unscrupulous regimes and nefarious non-state actors. This chapter examines the international conventional arms trade, the range of tools that have been used to control it, and challenges to these international regimes.

  12. Protection of Non-Trade Values in WTO Appellate Body Jurisprudence

    DEFF Research Database (Denmark)

    Andersen, Henrik

    2015-01-01

    of economic externality assessments in subsidy determinations. It is, however, still unsettled how other vital values, like those which can fall under peremptory norms, can be protected by the Appellate Body and whether its current approach provides the necessary tools for their protection.......The article suggests that the constitutional scope of the WTO leaves a wide space for the Appellate Body to protect non-trade values. That has, to some extent, materialized in Appellate Body practice; human health and environment are attaining general protection across the WTO treaties....... They are recognized as vital and important values and protected through the exceptions in the WTO treaties. However, the Appellate Body has also found ways to protect those values without resorting to the exceptions. Instead, they are part of an economic argument in national treatment analyses and they are part...

  13. 75 FR 34484 - In the Matter of: Certain Portable Electronic Devices and Related Software; Notice of Investigation

    Science.gov (United States)

    2010-06-17

    ... INTERNATIONAL TRADE COMMISSION [Inv. No. 337-TA-721] In the Matter of: Certain Portable Electronic Devices and Related Software; Notice of Investigation AGENCY: U.S. International Trade Commission. ACTION... filed with the U.S. International Trade Commission on May 12, 2010, under section 337 of the Tariff Act...

  14. 78 FR 22516 - Notice of Request for Stakeholder Comments on Doing Business in Africa Campaign

    Science.gov (United States)

    2013-04-16

    ... DEPARTMENT OF COMMERCE International Trade Administration Notice of Request for Stakeholder Comments on Doing Business in Africa Campaign AGENCY: International Trade Administration, Department of... comments on key stakeholder priorities to be considered in the development and implementation of an...

  15. Trade agreements with side-effects? : European Union and United States to negotiate Transatlantic Trade and Investment Partnership

    OpenAIRE

    Mildner, Stormy-Annika; Schmucker, Claudia

    2013-01-01

    "At the G8 summit in Northern Ireland on June 17, the European Union and the United States kicked off the negotiations for a comprehensive Transatlantic Trade and Investment Partnership (TTIP) to reduce tariffs and non-tariff trade barriers. While the expected economic benefits for both sides would be more than welcome in an era of gloomy growth forecasts, a TTIP is not entirely without risks for global trade and the multilateral trading system. The talks could tie up a considerable portion o...

  16. 77 FR 50716 - Certain Food Waste Disposers and Components and Packaging Thereof; Notice of Commission...

    Science.gov (United States)

    2012-08-22

    ... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-838] Certain Food Waste Disposers and Components and Packaging Thereof; Notice of Commission Determination Not to Review an Initial Determination Granting Complainant's Motions To Amend the Notice of Investigation and Complaint AGENCY: U.S...

  17. Relationships of the Trade Unions with the Media: The Lithuanian Case

    Directory of Open Access Journals (Sweden)

    Asta Krašenkienė

    2014-01-01

    Full Text Available The various practices of different countries show that, in order to achieve trade unions’ goals, working relationships with the media are very important, especially in terms of influencing public (stakeholder opinion, as well as instilling confidence in trade unions. This paper presents some examples and empirical research results that prove the significance of such relationships. The situation in Lithuania is analyzed based on qualitative research results. The results reveal that Lithuanian trade unions do not have effective tools at their disposal for the promotion of their activity. Moreover, their notion of their relationships with the media is limited to a narrow understanding such as “the article or broadcast in media”. Due to this and other reasons, the promotion of employers’ concessions is weak. Different situations can be noticed by analyzing the independent trade unions which use other practices and systems.

  18. 77 FR 67833 - Certain Radio Frequency Integrated Circuits and Devices Containing Same; Notice of Commission...

    Science.gov (United States)

    2012-11-14

    ... INTERNATIONAL TRADE COMMISSION [Investigation No. 337-TA-848] Certain Radio Frequency Integrated Circuits and Devices Containing Same; Notice of Commission Determination Not To Review an Initial Determination Terminating the Investigation in its Entirety AGENCY: U.S. International Trade Commission. ACTION...

  19. Analysis of NOx Budget Trading Program Units Brought into the CAIR NOx Ozone Season Trading Program

    Science.gov (United States)

    EPA analyzed the effect of having the large non-EGU units in the NBP and the CAIR NOX ozone season trading program and evaluated whether or not emissions from this group of units were reduced as a result of their inclusion in those trading programs.

  20. 32 CFR 9.9 - Protection of State secrets.

    Science.gov (United States)

    2010-07-01

    ... FOR TRIALS BY MILITARY COMMISSIONS OF CERTAIN NON-UNITED STATES CITIZENS IN THE WAR AGAINST TERRORISM § 9.9 Protection of State secrets. Nothing in this part shall be construed to authorize disclosure of... 32 National Defense 1 2010-07-01 2010-07-01 false Protection of State secrets. 9.9 Section 9.9...

  1. Autophagy Mediates Interleukin-1β Secretion in Human Neutrophils

    Directory of Open Access Journals (Sweden)

    Leonardo Iula

    2018-02-01

    Full Text Available Interleukin-1β (IL-1β, a major pro-inflammatory cytokine, is a leaderless cytosolic protein whose secretion does not follow the classical endoplasmic reticulum-to-Golgi pathway, and for which a canonical mechanism of secretion remains to be established. Neutrophils are essential players against bacterial and fungi infections. These cells are rapidly and massively recruited from the circulation into infected tissues and, beyond of displaying an impressive arsenal of toxic weapons effective to kill pathogens, are also an important source of IL-1β in infectious conditions. Here, we analyzed if an unconventional secretory autophagy mechanism is involved in the exportation of IL-1β by these cells. Our findings indicated that inhibition of autophagy with 3-methyladenine and Wortmannin markedly reduced IL-1β secretion induced by LPS + ATP, as did the disruption of the autophagic flux with Bafilomycin A1 and E64d. These compounds did not noticeable affect neutrophil viability ruling out that the effects on IL-1β secretion were due to cell death. Furthermore, VPS34IN-1, a specific autophagy inhibitor, was still able to reduce IL-1β secretion when added after it was synthesized. Moreover, siRNA-mediated knockdown of ATG5 markedly reduced IL-1β secretion in neutrophil-differentiated PLB985 cells. Upon LPS + ATP stimulation, IL-1β was incorporated to an autophagic compartment, as was revealed by its colocalization with LC3B by confocal microscopy. Overlapping of IL-1β-LC3B in a vesicular compartment peaked before IL-1β increased in culture supernatants. On the other hand, stimulation of autophagy by cell starvation augmented the colocalization of IL-1β and LC3B and then promoted neutrophil IL-1β secretion. In addition, specific ELISAs indicated that although both IL-1β and pro-IL-1β are released to culture supernatants upon neutrophil stimulation, autophagy only promotes IL-1β secretion. Furthermore, the serine proteases inhibitor

  2. Noticing cigarette health warnings and support for new health warnings among non-smokers in China: findings from the International Tobacco Control project (ITC China survey

    Directory of Open Access Journals (Sweden)

    Zejun Li

    2017-05-01

    Full Text Available Abstract Background Health warnings labels (HWLs have the potential to effectively communicate the health risks of smoking to smokers and non-smokers, and encourage smokers to quit. This study sought to examine whether non-smokers in China notice the current text-only HWLs and whether they support adding more health information and including pictures on HWLs. Methods Adult non-smokers (n = 1324 were drawn from Wave 4 (September 2011–November 2012 of the International Tobacco Control (ITC China Survey. The proportion of non-smokers who noticed the HWLs, and supported adding more health information and pictures to the HWLs was examined. Additionally, the relation between non-smokers’ demographic characteristics, including whether they had a smoking partner, their number of smoking friends, and noticing the HWLs and support for adding health information and pictures was examined. Because the HWLs changed during the survey period (April 2012, differences between non-smokers who completed the survey before and after the change were examined. Results 12.2% reported they noticed the HWLs often in the last month. The multivariate model, adjusting for demographics showed that respondents with a smoking partner (OR = 2.41, 95% CI 1.42–4.13, p = 0.001 noticed the HWLs more often. 64.8% of respondents agreed that the HWLs should have more information, and 80.2% supported including pictures. The multivariate model showed that non-smokers who completed the survey after the HWLs were implemented (OR = 0.63, 95% CI 0.40–0.99, p = 0.04 were less likely to support adding more health information. The multivariate model showed a significant relation between having a smoking partner and supporting pictorial HWLs (OR = 2.03, 95% CI 1.24–3.33, p = 0.005. Conclusions The findings indicate that the Chinese HWLs are noticed by a minority of non-smokers and that non-smokers strongly support strengthening the Chinese warning labels with more health

  3. Binomial model for measuring expected credit losses from trade receivables in non-financial sector entities

    Directory of Open Access Journals (Sweden)

    Branka Remenarić

    2018-01-01

    Full Text Available In July 2014, the International Accounting Standards Board (IASB published International Financial Reporting Standard 9 Financial Instruments (IFRS 9. This standard introduces an expected credit loss (ECL impairment model that applies to financial instruments, including trade and lease receivables. IFRS 9 applies to annual periods beginning on or after 1 January 2018 in the European Union member states. While the main reason for amending the current model was to require major banks to recognize losses in advance of a credit event occurring, this new model also applies to all receivables, including trade receivables, lease receivables, related party loan receivables in non-financial sector entities. The new impairment model is intended to result in earlier recognition of credit losses. The previous model described in International Accounting Standard 39 Financial instruments (IAS 39 was based on incurred losses. One of the major questions now is what models to use to predict expected credit losses in non-financial sector entities. The purpose of this paper is to research the application of the current impairment model, the extent to which the current impairment model can be modified to satisfy new impairment model requirements and the applicability of the binomial model for measuring expected credit losses from accounts receivable.

  4. Trade Mechanism Selection in Markets with Frictions

    OpenAIRE

    Gabriele Camera; Alain Delacroix

    2004-01-01

    We endogenize the trade mechanism in a search economy with many homogenous sellers and many heterogeneous buyers of unobservable type. We study how heterogeneity and the traders' continuation values -- which are endogenous -- influence the sellers' choice of trade mechanism. Sellers trade off the probability of an immediate sale against the surplus expected from it, choosing whether to trade with everyone and how quickly. In equilibrium sellers may simply target one buyer type via non-negotia...

  5. Yet Another Trading Simulation: The nonimmediacy Model

    OpenAIRE

    Jeyasreedharan, Nagaratnam

    2007-01-01

    Market participants who want to trade “quickly” demand transactional liquidity. Market participants who demand to trade “immediately” demand transactional immediacy. Traders supply immediacy when the trading returns are high and demand immediacy when the trading returns are low. Traders supply immediacy by being non-immediate and traders demand immediacy by being immediate. As these time-based expectations are functions of the underlying distributions of the clearing prices, one is able to de...

  6. Electricity as a traded good

    International Nuclear Information System (INIS)

    Srinivasan, Sunderasan

    2013-01-01

    Electric power has traditionally been classified as a non-traded good, produced and consumed within the country of origin. More recently, electricity has been traded across national borders and in certain cases, viz., Bhutan, has been the dominant export; in other situations, it is used to repay debts owed to neighboring countries. This paper investigates the role of electricity as the primary export, analyzes its valuation, and then goes on to evaluate the impact on the terms of trade. We conclude that in the medium-term, the electric power exporting economy would be better off developing its manufacturing sector to diversify its exposure and to protect its trade interests. The case of Bhutanese hydro-electricity exports to India is studied and the change in trade advantage with every increase in power tariff is ascertained. It is found that a 1.26% annual increase in (non-food) consumer prices is correlated with a 1% increase in electricity export tariff. While the causality from electric power tariff to Indian manufactures prices is not established statistically, a change in manufactures prices feeding back into consumer prices in Bhutan is statistically significant. Suggestions are offered for Bhutan to reduce dependence on Indian imports and to diversify its export market exposure. - Highlights: • Electricity as principal export of small economy. • Bilateral trade with large economy. • Tourism as major income generator for small economy. • Partial equilibrium model involving key variables. • Small economy would need to diversify. • Important subject for inter-temporal and inter-regional trade of power

  7. 75 FR 45623 - Morris Energy Group, LLC v.PSEG Energy Resources & Trade LLC; PSEG Fossil LLC; and PSEG Power LLC...

    Science.gov (United States)

    2010-08-03

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. EL10-79-000] Morris Energy Group, LLC v.PSEG Energy Resources & Trade LLC; PSEG Fossil LLC; and PSEG Power LLC; Notice of Complaint...) filed a complaint against PSEG Energy Resources & Trade, LLC, PSEG Fossil LLC and PSEG Power LLC (PSEG...

  8. 78 FR 20931 - National Institute of Environmental Health Sciences; Notice of Meeting

    Science.gov (United States)

    2013-04-08

    ... attendance limited to space available. Individuals who plan to attend and need special assistance, such as... applications and the discussions could disclose confidential trade secrets or commercial property such as...

  9. Cultural Effects of Trade Liberalization

    OpenAIRE

    Steven M. Suranovic; Robert Winthrop

    2005-01-01

    We incorporate culture into a standard trade model in two distinct ways. In the ¡°cultural affinity from work¡± model, workers receive a non- pecuniary cultural benefit from work in a particular industry. In the ¡°cultural externality¡± model, consumers of a product receive utility from other consumer¡¯s consumption of a domestic good. We show that resistance to change due to cultural concerns can reduce the national benefits from trade liberalization. Complete movements to free trade will ha...

  10. 75 FR 54642 - National Eye Institute; Notice of Meeting

    Science.gov (United States)

    2010-09-08

    ... public as indicated below, with attendance limited to space available. Individuals who plan to attend and... disclose confidential trade secrets or commercial property such as patentable material, and personal... concerning Institute programs. Place: Melrose Hotel, 2430 Pennsylvania Ave., NW., Washington, DC 20037...

  11. 78 FR 7795 - Fogarty International Center; Notice of Meeting

    Science.gov (United States)

    2013-02-04

    ... meeting will be open to the public as indicated below, with attendance limited to space available... discussions could disclose confidential trade secrets or commercial property such as patentable materials, and... posted when available. (Catalogue of Federal Domestic Assistance Program Nos. 93.106, Minority...

  12. 76 FR 18567 - Fogarty International Center; Notice of Meeting

    Science.gov (United States)

    2011-04-04

    ... meeting will be open to the public as indicated below, with attendance limited to space available... confidential trade secrets or commercial property such as patentable materials, and personal information... be posted when available. (Catalogue of Federal Domestic Assistance Program Nos. 93.14, Intramural...

  13. 78 FR 26642 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-05-07

    ...., as amended. The grant applications and the discussions could disclose confidential trade secrets or... Review Group; Sensorimotor Integration Study Section. Date: June 4, 2013. Time: 8:00 a.m. to 6:00 p.m...

  14. 78 FR 45181 - North American Free Trade Agreement (NAFTA), Article 1904 Binational Panel Reviews: Notice of...

    Science.gov (United States)

    2013-07-26

    ... DEPARTMENT OF COMMERCE International Trade Administration North American Free Trade Agreement..., (202) 482-5438. SUPPLEMENTARY INFORMATION: Chapter 19 of the North American Free Trade Agreement... Secretariat, United States Section, International Trade Administration, Department of Commerce. ACTION: On...

  15. Permit trading and credit trading

    DEFF Research Database (Denmark)

    Boom, Jan-Tjeerd; R. Dijstra, Bouwe

    This paper compares emissions trading based on a cap on total emissions (permit trading) and on relative standards per unit of output (credit trading). Two types of market structure are considered: perfect competition and Cournot oligopoly. We find that output, abatement costs and the number...... of firms are higher under credit trading. Allowing trade between permit-trading and credit-trading sectors may increase in welfare. With perfect competition, permit trading always leads to higher welfare than credit trading. With imperfect competition, credit trading may outperform permit trading....... Environmental policy can lead to exit, but also to entry of firms. Entry and exit have a profound impact on the performance of the schemes, especially under imperfect competition. We find that it may be impossible to implement certain levels of total industry emissions. Under credit trading several levels...

  16. Nutrition labelling is a trade policy issue: lessons from an analysis of specific trade concerns at the World Trade Organization.

    Science.gov (United States)

    Thow, Anne Marie; Jones, Alexandra; Hawkes, Corinna; Ali, Iqra; Labonté, Ronald

    2017-01-12

    Interpretive nutrition labels provide simplified nutrient-specific text and/or symbols on the front of pre-packaged foods, to encourage and enable consumers to make healthier choices. This type of labelling has been proposed as part of a comprehensive policy response to the global epidemic of non-communicable diseases. However, regulation of nutrition labelling falls under the remit of not just the health sector but also trade. Specific Trade Concerns have been raised at the World Trade Organization's Technical Barriers to Trade Committee regarding interpretive nutrition labelling initiatives in Thailand, Chile, Indonesia, Peru and Ecuador. This paper presents an analysis of the discussions of these concerns. Although nutrition labelling was identified as a legitimate policy objective, queries were raised regarding the justification of the specific labelling measures proposed, and the scientific evidence for effectiveness of such measures. Concerns were also raised regarding the consistency of the measures with international standards. Drawing on policy learning theory, we identified four lessons for public health policy makers, including: strategic framing of nutrition labelling policy objectives; pro-active policy engagement between trade and health to identify potential trade issues; identifying ways to minimize potential 'practical' trade concerns; and engagement with the Codex Alimentarius Commission to develop international guidance on interpretative labelling. This analysis indicates that while there is potential for trade sector concerns to stifle innovation in nutrition labelling policy, care in how interpretive nutrition labelling measures are crafted in light of trade commitments can minimize such a risk and help ensure that trade policy is coherent with nutrition action. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  17. 77 FR 6169 - Defense Trade Advisory Group; Notice of Membership

    Science.gov (United States)

    2012-02-07

    ...-Military Affairs with a formal channel for regular consultation and coordination with U.S. private sector... defense trade and industrial competitiveness, and all members must be able to advise the Bureau on these...

  18. 78 FR 73867 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2013-12-09

    ...., as amended. The grant applications and the discussions could disclose confidential trade secrets or...: Integration and Analysis of Diverse HIV- Associated Data (R03). Date: December 16, 2013. Time: 8:00 a.m. to 5...

  19. 75 FR 65546 - Self-Regulatory Organizations; National Securities Clearing Corporation; Notice of Filing of...

    Science.gov (United States)

    2010-10-25

    ....\\3\\ The Commission is publishing this notice to solicit comments on the proposed rule change from...., ``don't know'' or ``DK'' obligations) in an efficient and timely manner. As proposed, OW will... trade-for-trade. \\8\\ FINRA Rule 11190(a). RECAPS provides reject and DK capabilities for advisories...

  20. Strategic partitioning of emission allowances under the EU Emission Trading Scheme

    Energy Technology Data Exchange (ETDEWEB)

    Boehringer, Christoph [Univ. of Oldenburg, Department of Economics, and Centre for European Economic Research (ZEW) (Germany); Rosendahl, Knut Einar [Statistics Norway, Research Department, Pob. 8131 Dep., N-0033 Oslo (Norway)

    2009-08-15

    The EU Emission Trading Scheme (ETS) is breaking new ground in the experience with emission trading regimes across multiple jurisdictions. Since the EU ETS covers only some industries, it implies a hybrid emission control scheme where EU member states must apply complementary domestic emissions regulation for the non-trading sectors of their economies in order to comply with their national emission reduction targets. The EU ETS thus opens up for strategic partitioning of national emissions budgets by the member states between trading and non-trading sectors. In this paper we examine the potential effects of such strategic behavior on compliance cost and emissions prices. We show that concerns on efficiency losses from strategic partitioning are misplaced. In turn, our analysis implicitly indicates significant political economy forces behind EU climate policy, as both cost-effective and strategically motivated partitioning of national emission budgets are far off from the actual break-down between trading and non-trading sectors. (author)

  1. 77 FR 50516 - Fogarty International Center; Notice of Meetings

    Science.gov (United States)

    2012-08-21

    ... Board. The meeting will be open to the public as indicated below, with attendance limited to space... and the discussions could disclose confidential trade secrets or commercial property such as... Federal Domestic Assistance Program Nos. 93.106, Minority International Research Training Grant in the...

  2. 78 FR 50426 - Fogarty International Center; Notice of Meeting

    Science.gov (United States)

    2013-08-19

    ... meeting will be open to the public as indicated below, with attendance limited to space available... discussions could disclose confidential trade secrets or commercial property such as patentable materials, and... Assistance Program Nos. 93.106, Minority International Research Training Grant in the Biomedical and...

  3. 77 FR 1705 - Fogarty International Center; Notice of Meetings

    Science.gov (United States)

    2012-01-11

    ... meeting will be open to the public as indicated below, with attendance limited to space available... discussions could disclose confidential trade secrets or commercial property such as patentable materials, and... of Federal Domestic Assistance Program Nos. 93.106, Minority International Research Training Grant in...

  4. 78 FR 73867 - National Eye Institute; Notice of Meeting

    Science.gov (United States)

    2013-12-09

    ... open to the public as indicated below, with attendance limited to space available. Individuals who plan... discussions could disclose confidential trade secrets or commercial property such as patentable material, and... concerning Institute programs. Place: National Institutes of Health, Rockledge II Building, Room 9100/9104...

  5. Degree-strength correlation reveals anomalous trading behavior.

    Science.gov (United States)

    Sun, Xiao-Qian; Shen, Hua-Wei; Cheng, Xue-Qi; Wang, Zhao-Yang

    2012-01-01

    Manipulation is an important issue for both developed and emerging stock markets. Many efforts have been made to detect manipulation in stock markets. However, it is still an open problem to identify the fraudulent traders, especially when they collude with each other. In this paper, we focus on the problem of identifying the anomalous traders using the transaction data of eight manipulated stocks and forty-four non-manipulated stocks during a one-year period. By analyzing the trading networks of stocks, we find that the trading networks of manipulated stocks exhibit significantly higher degree-strength correlation than the trading networks of non-manipulated stocks and the randomized trading networks. We further propose a method to detect anomalous traders of manipulated stocks based on statistical significance analysis of degree-strength correlation. Experimental results demonstrate that our method is effective at distinguishing the manipulated stocks from non-manipulated ones. Our method outperforms the traditional weight-threshold method at identifying the anomalous traders in manipulated stocks. More importantly, our method is difficult to be fooled by colluded traders.

  6. Degree-strength correlation reveals anomalous trading behavior.

    Directory of Open Access Journals (Sweden)

    Xiao-Qian Sun

    Full Text Available Manipulation is an important issue for both developed and emerging stock markets. Many efforts have been made to detect manipulation in stock markets. However, it is still an open problem to identify the fraudulent traders, especially when they collude with each other. In this paper, we focus on the problem of identifying the anomalous traders using the transaction data of eight manipulated stocks and forty-four non-manipulated stocks during a one-year period. By analyzing the trading networks of stocks, we find that the trading networks of manipulated stocks exhibit significantly higher degree-strength correlation than the trading networks of non-manipulated stocks and the randomized trading networks. We further propose a method to detect anomalous traders of manipulated stocks based on statistical significance analysis of degree-strength correlation. Experimental results demonstrate that our method is effective at distinguishing the manipulated stocks from non-manipulated ones. Our method outperforms the traditional weight-threshold method at identifying the anomalous traders in manipulated stocks. More importantly, our method is difficult to be fooled by colluded traders.

  7. 78 FR 64260 - Overseas Security Advisory Council (OSAC) Meeting Notice

    Science.gov (United States)

    2013-10-28

    ... corporate security policies and procedures and will involve extensive discussion of trade secrets and proprietary commercial information that is privileged and confidential, and will discuss law enforcement... protection of U.S. business information overseas. For more information, contact Marsha Thurman, Overseas...

  8. 76 FR 24499 - National Eye Institute; Notice of Closed Meeting

    Science.gov (United States)

    2011-05-02

    ... the public as indicated below, with attendance limited to space available. Individuals who plan to... disclose confidential trade secrets or commercial property such as patentable material, and personal... discussions concerning Institute programs. Place: National Institutes of Health, 5635 Fishers Lane, Terrace...

  9. 77 FR 31032 - National Eye Institute; Notice of Closed Meeting

    Science.gov (United States)

    2012-05-24

    ... the public as indicated below, with attendance limited to space available. Individuals who plan to... disclose confidential trade secrets or commercial property such as patentable material, and personal... concerning Institute programs. Place: National Institutes of Health, 5635 Fishers Lane, Terrace Level...

  10. 77 FR 73037 - National Eye Institute; Notice of Closed Meeting

    Science.gov (United States)

    2012-12-07

    ... the public as indicated below, with attendance limited to space available. Individuals who plan to... disclose confidential trade secrets or commercial property such as patentable material, and personal... discussions concerning Institute programs. Place: National Institutes of Health, 5635 Fishers Lane, Terrace...

  11. 77 FR 55852 - National Eye Institute; Notice of Closed Meeting

    Science.gov (United States)

    2012-09-11

    ... the public as indicated below, with attendance limited to space available. Individuals who plan to... disclose confidential trade secrets or commercial property such as patentable material, and personal... concerning Institute programs. Place: National Institutes of Health, 5635 Fishers Lane, Terrace Level...

  12. 75 FR 76474 - National Eye Institute; Notice of Closed Meeting

    Science.gov (United States)

    2010-12-08

    ... the public as indicated below, with attendance limited to space available. Individuals who plan to... disclose confidential trade secrets or commercial property such as patentable material, and personal... concerning Institute programs. Place: National Institutes of Health, 5635 Fishers Lane, Terrace Level...

  13. 76 FR 53687 - National Eye Institute Notice of Closed Meeting

    Science.gov (United States)

    2011-08-29

    ... the public as indicated below, with attendance limited to space available. Individuals who plan to... disclose confidential trade secrets or commercial property such as patentable material, and personal... concerning Institute programs. Place: National Institutes of Health, 5635 Fishers Lane, Terrace Level...

  14. 77 FR 2076 - National Eye Institute; Notice of Closed Meeting

    Science.gov (United States)

    2012-01-13

    ... the public as indicated below, with attendance limited to space available. Individuals who plan to... disclose confidential trade secrets or commercial property such as patentable material, and personal... concerning Institute programs. Place: National Institutes of Health, 5635 Fishers Lane, Terrace Level...

  15. A simple test for PPP among traded goods

    NARCIS (Netherlands)

    Ph.H.B.F. Franses (Philip Hans); D.J.C. van Dijk (Dick)

    2002-01-01

    textabstractThe so-called Balassa-Samuelson model implies that relative prices of non-traded goods may be nonstationary and, hence, that PPP should preferably be tested on real exchange rates based on prices of traded goods only. We propose a simple test for PPP among traded goods which can be

  16. 77 FR 31683 - Notice of Effective Date of Modifications to a Rule of Origin of the United States-Australia Free...

    Science.gov (United States)

    2012-05-29

    ... Rule of Origin of the United States-Australia Free Trade Agreement AGENCY: Office of the United States Trade Representative. ACTION: Notice of effective date for goods of Australia of certain modifications to a product-specific rule of origin under the United States-Australia Free Trade Agreement (USAFTA...

  17. Informing decision makers and identifying niche opportunities for windpower: use of multiattribute trade off analysis to evaluate non-dispatchable resources

    International Nuclear Information System (INIS)

    Connors, S.R.

    1996-01-01

    The operational and flexibility characteristics of renewable energy technologies are often overlooked in traditional head to head technology comparisons. This impedes their adoption since identification of environmental and risk mitigation advantages requires evaluation of such non-dispatchable technologies in a systemwide context. Use of multiattribute resource planning tools in a trade off analysis framework identifies the complementary emissions reduction and fuel diversification characteristics of renewables. Data visualization using trade off analysis communicates electric resource interactions and the risks of following various strategies to diverse stakeholder audiences, promoting acceptance. This paper provides an overview of the multiattribute trade off approach and applies it to resource strategies incorporating windpower in the New England regional power system. Examples focus on the interaction of wind resources with demand-side management and supply-side options under fuel cost uncertainty. (Author)

  18. International Emission Trading Systems: Trade Level and Political Acceptability

    DEFF Research Database (Denmark)

    Boom, J-T.; Svendsen, Gert Tinggaard

    1999-01-01

    , at the international level, industrial lobbyism was non-significant. Only the 'fossil fuel lobby' played a role. Third, at the national level, one could expect strong political opposition from industry lobbies in case quotas are actually to be distributed at firm level. But trade among countries may benefit industry...

  19. 75 FR 23223 - Meetings of the Agricultural Policy Advisory Committee for Trade and the Agricultural Technical...

    Science.gov (United States)

    2010-05-03

    ...Notice is hereby given that the Agricultural Policy Advisory Committee for Trade (APAC) and the Agricultural Technical Advisory Committees for Trade (ATACs) will hold closed meetings on May 6, 2010. The advisory committees are administered by the U.S. Department of Agriculture and the Office of the United States Trade Representative (USTR). The meetings are closed to the public in accordance with the Trade Act of 1974, 19 U.S.C. 2155(f)(2), and the Government in the Sunshine Act, 5 U.S.C. 552b(c)(4)(6). USTR has determined that public access to the meetings would seriously compromise the development by the U.S. government of trade policy priorities, negotiating objectives, or bargaining positions with respect to the operation of trade agreements and other matters arising in connection with the development, implementation, and administration of the trade policy of the United States. Topics will include Doha Round negotiations in the World Trade Organization (WTO), WTO accession negotiations, and negotiations in bilateral and regional free trade agreements.

  20. 75 FR 16075 - Certain Preserved Mushrooms From the People's Republic of China: Notice of Initiation of...

    Science.gov (United States)

    2010-03-31

    ... DEPARTMENT OF COMMERCE International Trade Administration [A-570-851] Certain Preserved Mushrooms... order on certain preserved mushrooms from the People's Republic of China (PRC). See Notice of Amendment... antidumping duty order on certain preserved mushrooms from the PRC. See Notice of Amendment of Final...

  1. Liability rules for international trading of greenhouse gas emissions quotas

    DEFF Research Database (Denmark)

    Haites, E.; Missfeldt, F.

    2001-01-01

    To reduce the costs of mitigating greenhouse gas emissions in accordance with the Kyoto protocol, international trades of emissions quotas are allowed. The revenue from the sale of quotas may exceed the sanctions for non-compliance if these penalties are weak or poorly enforced. Under...... these circumstances emissions trading enables a country to benefit financially through non-compliance. To counter non-compliance due to trading a range of liability proposals have been suggested. Using a simple global model, we analyze the economic and environmental performance of these proposals for the first...

  2. Impaired insulin secretion in the spontaneous diabetes rats.

    Science.gov (United States)

    Kimura, K; Toyota, T; Kakizaki, M; Kudo, M; Takebe, K; Goto, Y

    1982-08-01

    Dynamics of insulin and glucagon secretion were investigated by using a new model of spontaneous diabetes rats produced by the repetition of selective breeding in our laboratories. The perfusion experiments of the pancreas showed that the early phase of insulin secretion to continuous stimulation with glucose was specifically impaired, although the response of the early phase to arginine was preserved. The glucose-induced insulin secretion in the nineth generation (F8) which had a more remarkably impaired glucose tolerance was more reduced than in the sixth generation (F5). No significant difference of glucagon secretion in response to arginine or norepinephrine was noted between the diabetes rats and control ones. The present data indicate that the defective insulin secretion is a primary derangement in a diabetic state of the spontaneous diabetes rat. This defect in the early phase of glucose-induced insulin secretion suggests the specific impairment of the recognition of glucose by the pancreatic beta-cells. The spontaneous diabetes rats are very useful as a model of disease for investigating pathophysiology of non-insulin dependent diabetes mellitus.

  3. E-commerce trade in invasive plants.

    Science.gov (United States)

    Humair, Franziska; Humair, Luc; Kuhn, Fabian; Kueffer, Christoph

    2015-12-01

    Biological invasions are a major concern in conservation, especially because global transport of species is still increasing rapidly. Conservationists hope to anticipate and thus prevent future invasions by identifying and regulating potentially invasive species through species risk assessments and international trade regulations. Among many introduction pathways of non-native species, horticulture is a particularly important driver of plant invasions. In recent decades, the horticultural industry expanded globally and changed structurally through the emergence of new distribution channels, including internet trade (e-commerce). Using an automated search algorithm, we surveyed, on a daily basis, e-commerce trade on 10 major online auction sites (including eBay) of approximately three-fifths of the world's spermatophyte flora. Many recognized invasive plant species (>500 species) (i.e., species associated with ecological or socio-economic problems) were traded daily worldwide on the internet. A markedly higher proportion of invasive than non-invasive species were available online. Typically, for a particular plant family, 30-80% of recognized invasive species were detected on an auction site, but only a few percentages of all species in the plant family were detected on a site. Families that were more traded had a higher proportion of invasive species than families that were less traded. For woody species, there was a significant positive relationship between the number of regions where a species was sold and the number of regions where it was invasive. Our results indicate that biosecurity is not effectively regulating online plant trade. In the future, automated monitoring of e-commerce may help prevent the spread of invasive species, provide information on emerging trade connectivity across national borders, and be used in horizon scanning exercises for early detection of new species and their geographic source areas in international trade. © 2015 Society for

  4. 78 FR 33456 - Self-Regulatory Organizations; Fixed Income Clearing Corporation; Notice of Filing Proposed Rule...

    Science.gov (United States)

    2013-06-04

    ... certain locked- in trade sources in the future based on volumes and processing costs. \\9\\ Designated...-Regulatory Organizations; Fixed Income Clearing Corporation; Notice of Filing Proposed Rule Change to Include trueEX LLC as a Designated Locked-In Trade Source Pursuant to the Rulebook of the Government Securities...

  5. 78 FR 56657 - Notice of Solicitation of Applications for Allocation of Tariff Rate Quotas on the Import of...

    Science.gov (United States)

    2013-09-13

    ... DEPARTMENT OF COMMERCE International Trade Administration Notice of Solicitation of Applications...: International Trade Administration, Department of Commerce. ACTION: The Department of Commerce (``Department... 30003, U.S. Department of Commerce, 1401 Constitution Ave. NW., Washington, DC 20230 (telephone: (202...

  6. 78 FR 56658 - Notice of Solicitation of Applications for Allocation of Tariff Rate Quotas on the Import of...

    Science.gov (United States)

    2013-09-13

    ... DEPARTMENT OF COMMERCE International Trade Administration Notice of Solicitation of Applications... Weave Such Fabrics in the United States AGENCY: Department of Commerce, International Trade Administration. ACTION: The Department of Commerce (Department) is soliciting applications for an allocation of...

  7. 78 FR 27408 - National Cancer Institute; Notice of Closed Meetings

    Science.gov (United States)

    2013-05-10

    ...., as amended. The contract proposals and the discussions could disclose confidential trade secrets or... with the contract proposals, the disclosure of which would constitute a clearly unwarranted invasion of personal privacy. Name of Committee: National Cancer Institute Special Emphasis Panel; SBIR Topic 304...

  8. 76 FR 78285 - National Institute on Aging; Notice of Meeting

    Science.gov (United States)

    2011-12-16

    ... be open to the public as indicated below, with attendance limited to space available. Individuals who... disclose confidential trade secrets or commercial property such as patentable material, and personal... Working Group on Program; council speaker; and Program Highlights. Place: National Institutes of Health...

  9. Trade in non-native, CITES-listed, wildlife in Asia, as exemplified by the trade in freshwater turtles and tortoises (Chelonidae) in Thailand

    NARCIS (Netherlands)

    Nijman, V.; Shepherd, C.R.

    2007-01-01

    In 1973 the Convention in International Trade in Endangered Species of Wild Fauna and Flora (CITES) was called to life as to regulate the international wildlife trade, and to prevent species becoming (economically and biologically) extinct. The trade in freshwater turtles and tortoises in Asia is so

  10. 76 FR 52862 - Courtesy Notice of Liquidation; Correction

    Science.gov (United States)

    2011-08-24

    ... discontinuation of electronic courtesy notices of liquidation to importers of record whose entry summaries are... a misstatement in a comment response regarding the availability to an importer of an Importer Trade... implementation through electronic notification (see CBP.gov ). FOR FURTHER INFORMATION CONTACT: Laurie Dempsey...

  11. THE BUFFER CAPACITY OF AIRWAY EPITHELIAL SECRETIONS

    Directory of Open Access Journals (Sweden)

    Dusik eKim

    2014-06-01

    Full Text Available The pH of airway epithelial secretions influences bacterial killing and mucus properties and is reduced by acidic pollutants, gastric reflux, and respiratory diseases such as cystic fibrosis (CF. The effect of acute acid loads depends on buffer capacity, however the buffering of airway secretions has not been well characterized. In this work we develop a method for titrating micro-scale (30 µl volumes and use it to study fluid secreted by the human airway epithelial cell line Calu-3, a widely used model for submucosal gland serous cells. Microtitration curves revealed that HCO3- is the major buffer. Peak buffer capacity (β increased from 17 to 28 mM/pH during forskolin stimulation, and was reduced by >50% in fluid secreted by cystic fibrosis transmembrane conductance regulator (CFTR-deficient Calu-3 monolayers, confirming an important role of CFTR in HCO3- secretion. Back-titration with NaOH revealed non-volatile buffer capacity due to proteins synthesized and released by the epithelial cells. Lysozyme and mucin concentrations were too low to buffer Calu-3 fluid significantly, however model titrations of porcine gastric mucins at concentrations near the sol-gel transition suggest that mucins may contribute to the buffer capacity of ASL in vivo. We conclude that CFTR-dependent HCO3- secretion and epithelially-derived proteins are the predominant buffers in Calu-3 secretions.

  12. To trade or not to trade: Link prediction in the virtual water network

    Science.gov (United States)

    Tuninetti, Marta; Tamea, Stefania; Laio, Francesco; Ridolfi, Luca

    2017-12-01

    In the international trade network, links express the (temporary) presence of a commercial exchange of goods between any two countries. Given the dynamical behaviour of the trade network, where links are created and dismissed every year, predicting the link activation/deactivation is an open research question. Through the international trade network of agricultural goods, water resources are 'virtually' transferred from the country of production to the country of consumption. We propose a novel methodology for link prediction applied to the network of virtual water trade. Starting from the assumption of having links between any two countries, we estimate the associated virtual water flows by means of a gravity-law model using country and link characteristics as drivers. We consider the links with estimated flows higher than 1000 m3/year as active links, while the others as non-active links. Flows traded along estimated active links are then re-estimated using a similar but differently-calibrated gravity-law model. We were able to correctly model 84% of the existing links and 93% of the non-existing links in year 2011. It is worth to note that the predicted active links carry 99% of the global virtual water flow; hence, missed links are mainly those where a minimum volume of virtual water is exchanged. Results indicate that, over the period from 1986 to 2011, population, geographical distances between countries, and agricultural efficiency (through fertilizers use) are the major factors driving the link activation and deactivation. As opposed to other (network-based) models for link prediction, the proposed method is able to reconstruct the network architecture without any prior knowledge of the network topology, using only the nodes and links attributes; it thus represents a general method that can be applied to other networks such as food or value trade networks.

  13. Biological trade and markets.

    Science.gov (United States)

    Hammerstein, Peter; Noë, Ronald

    2016-02-05

    Cooperation between organisms can often be understood, like trade between merchants, as a mutually beneficial exchange of services, resources or other 'commodities'. Mutual benefits alone, however, are not sufficient to explain the evolution of trade-based cooperation. First, organisms may reject a particular trade if another partner offers a better deal. Second, while human trade often entails binding contracts, non-human trade requires unwritten 'terms of contract' that 'self-stabilize' trade and prevent cheating even if all traders strive to maximize fitness. Whenever trading partners can be chosen, market-like situations arise in nature that biologists studying cooperation need to account for. The mere possibility of exerting partner choice stabilizes many forms of otherwise cheatable trade, induces competition, facilitates the evolution of specialization and often leads to intricate forms of cooperation. We discuss selected examples to illustrate these general points and review basic conceptual approaches that are important in the theory of biological trade and markets. Comparing these approaches with theory in economics, it turns out that conventional models-often called 'Walrasian' markets-are of limited relevance to biology. In contrast, early approaches to trade and markets, as found in the works of Ricardo and Cournot, contain elements of thought that have inspired useful models in biology. For example, the concept of comparative advantage has biological applications in trade, signalling and ecological competition. We also see convergence between post-Walrasian economics and biological markets. For example, both economists and biologists are studying 'principal-agent' problems with principals offering jobs to agents without being sure that the agents will do a proper job. Finally, we show that mating markets have many peculiarities not shared with conventional economic markets. Ideas from economics are useful for biologists studying cooperation but need

  14. 75 FR 45693 - Request for Comments and Notice of Public Hearing Concerning China's Compliance With WTO Commitments

    Science.gov (United States)

    2010-08-03

    ..., government procurement, trade-related investment measures, taxes and charges levied on imports and exports... Concerning China's Compliance With WTO Commitments AGENCY: Office of the United States Trade Representative. ACTION: Request for comments and notice of public hearing concerning China's compliance with its WTO...

  15. 77 FR 50206 - Request for Comments and Notice of Public Hearing Concerning China's Compliance With WTO Commitments

    Science.gov (United States)

    2012-08-20

    ..., government procurement, trade-related investment measures, taxes and charges levied on imports and exports... Concerning China's Compliance With WTO Commitments AGENCY: Office of the United States Trade Representative. ACTION: Request for comments and notice of public hearing concerning China's compliance with its WTO...

  16. INSTITUTIONS, GOVERNANCE AND INTERNATIONAL TRADE

    Directory of Open Access Journals (Sweden)

    Henri L.F. de GROOT

    2005-01-01

    Full Text Available Ineffective institutions and bad governance increase transaction costs and reduce international transport flows. In this paper, we empirically investigate this basic notion, and we show that it can account for several, so far, somewhat puzzling results in the empirical literature estimating gravity equations of bilateral trade. More specifically, we show that differences in the quality and effectiveness of institutions offer an explanation for the tendency of OECD countries to trade disproportionately with each other, and with non-OECD countries, as well as for the positive effect of GDP per capita on bilateral trade.

  17. Transboundary Pollution, Trade Liberalization and Environmental Taxes

    NARCIS (Netherlands)

    Baksi, S.; Ray Chaudhuri, A.

    2008-01-01

    In a bilateral trade framework, we examine the impact of tariff reduction on the optimal pollution tax and social welfare when pollution is transboundary. Strategic considerations lead countries to distort their pollution tax in the non-cooperative equilibrium. Trade liberalization changes the

  18. International trade in nuclear fuel cycle services

    International Nuclear Information System (INIS)

    May, D.

    1989-01-01

    This paper analyses and discusses general trends in international trade in nuclear fuel cycle services with particular emphasis on the development of trading patterns between Europe, North America and the Far East. The paper also examines the role of collaborative ventures in the development of the nuclear industry. Barriers to international trade, the effect of government regulations and restrictions and the impact of non-proliferation issues are discussed. (author)

  19. 78 FR 2682 - National Cancer Institute; Notice of Meeting

    Science.gov (United States)

    2013-01-14

    ... be open to the public as indicated below, with attendance limited to space available. Individuals who... confidential trade secrets or commercial property such as patentable material, and personal information... Advisory Board. Open: February 8, 2013, 9:00 a.m. to 3:30 p.m. Agenda: Program reports and presentations...

  20. 77 FR 1549 - Generalized System of Preferences (GSP): Notice of the Results of the 2010 GSP Annual Review

    Science.gov (United States)

    2012-01-10

    ... OFFICE OF THE UNITED STATES TRADE REPRESENTATIVE Generalized System of Preferences (GSP): Notice...-free importation of eligible articles when imported from designated beneficiary developing countries... review and the recommendation of the U.S. Trade Representative, President Obama removed one product...

  1. [Primary study on characteristics of insulin secretion rate, metabolic clearance rate and sensitivity in non-insulin-dependent diabetic subjects from multiplex diabetic pedigrees].

    Science.gov (United States)

    Ran, J; Cheng, H; Li, F

    2000-01-01

    To investigate the characteristics of insulin secretion rate (ISR), metabolic clearance rate (MCR-I) and sensitivity and to explore their relationship with obesity in non-insulin-dependent diabetic subjects from multiplex diabetic pedigrees (MDP). Fifteen subjects with normal glucose tolerance and 11 non-insulin-dependent diabetic patients from MDP were included in the study. Frequently sampled intravenous glucose tolerance test (FSIVGTT) was performed. Glucose, insulin (INS) and connecting-peptide (C-P) concentrations were measured. A computer procedure devised by our laboratory was used to calculate the value of ISR at each time point, then MCR-I was acquired. Insulin sensitivity index (SI) was calculated according to minimal model technique about glucose in FSIVGTT. The ISR curve in control group was biphasic, while in non-insulin. In non-insulin-dependent diabetic group, areas under the curves of C-P (AUCC) and ISR level (AUCS) measured during 0 approximately 16 min were 7.9 nmol.min(-1).L(-1) +/- 2.8 nmol.min(-1).L(-1), and 6.1 nmol +/- 2.2 nmol, respectively, which were significantly lower than those in control group 17.7 nmol.min(-1).L(-1) +/- 4.92 nmol.min(-1).L(-1) and 12.3 nmol +/- 3.9 nmol (P < 0.01). The two parameters were slightly higher than those in control group 155 nmol.min(-1).L(-1) +/- 44 nmol.min(-1).L(-1) vs 101 nmol.min(-1).L(-1) +/- 30 nmol.min(-1).L(-1) and 76 nmol +/- 26 nmol vs 54 nmol +/- 20.0 nmol (P < 0.05)measured during 16 approximately 180 min. There was no significant difference, between the two groups about the amount of insulin secretion during 3 hours (82 nmol +/- 28nmol vs 68 nmol +/- 21 nmol, P = 0.2). In control group, there were significant positive correlation, between AUCS, waist-hip ratio (WHR), and body surface area, (BSA) and significant negative correlation between MCR-I, SI and WHR, BSA (P < 0.01), and also between MCR-I and SI. In non-insulin-dependent diabetic group, AUCS were significantly correlated with body mass

  2. Biotrade1: international trade in renewable energy from biomass

    NARCIS (Netherlands)

    Agterberg, A.E.; Faaij, A.P.C.

    1998-01-01

    This paper discusses international trade in renewable energy from biomass. Main objective is to compare options for international trade in energy from biomass and to compare these options with non-trade options like domestic use of biomass and afforestation. Aspects that are taken into account are

  3. Effect of the non-tariff barriers in the trade of Colombian mining goods

    International Nuclear Information System (INIS)

    Gamba Saavedra, Gloria Patricia

    2007-01-01

    The objective of this study is to identify and to provide information on the non tariff barriers NTB to a group of mining products on the excellent international markets for the Colombian case, and to analyze its magnitude and incidence on the external sales of this products, to advance toward this objective is defined which measures they can be considered as non tariff restrictions, its different mensuration methodologies are analyzed and finally a qualitative and quantitative approach of the NTB is made that face the exports of Colombian mining products in their main markets, by means of a survey carried out the managers of the sector in the country. Among the main discoveries, they were evidences of the application of NTB, although they turned out to be not very significant for the sector exporter of mining products; the most frequent are the technical obstacles to the trade, but of relatively moderate incidence

  4. 27 CFR 41.72 - Notice for smokeless tobacco.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Notice for smokeless tobacco. 41.72 Section 41.72 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY (CONTINUED) TOBACCO IMPORTATION OF TOBACCO PRODUCTS, CIGARETTE PAPERS...

  5. 27 CFR 40.216 - Notice for smokeless tobacco.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Notice for smokeless tobacco. 40.216 Section 40.216 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY (CONTINUED) TOBACCO MANUFACTURE OF TOBACCO PRODUCTS, CIGARETTE PAPERS...

  6. 76 FR 46791 - Combined Notice of Filings #1

    Science.gov (United States)

    2011-08-03

    ... Trading and Marketing, LLC, Duke Energy Vermillion II, LLC, Duke Energy Washington II, LLC, Happy Jack...] listed above, do not institute a proceeding regarding qualifying facility status. A notice of self... the FERC Online links at http://www.ferc.gov . To facilitate electronic service, persons with Internet...

  7. Transboundary Pollution, Trade Liberalization, and Environmental Taxes

    NARCIS (Netherlands)

    Baksi, S.; Ray Chaudhuri, A.

    2008-01-01

    In a bilateral trade framework, we examine the impact of tari¤ reduction on the op- timal pollution tax and social welfare when pollution is transboundary. Strategic considerations lead countries to distort their pollution tax in the non-cooperative equilibrium. Trade liberalization changes the

  8. 76 FR 30100 - Certain Frozen Warmwater Shrimp From the People's Republic of China: Notice of Amended Final...

    Science.gov (United States)

    2011-05-24

    ... Fair Value Pursuant to Court Decision AGENCY: Import Administration, International Trade Administration... (``Department'') Notice of Final Determination of Sales at Less Than Fair Value: Certain Frozen and Canned...'') and Notice of Amended Final Determination of Sales at Less Than Fair Value and Antidumping Duty Order...

  9. Clinical hyperthyroidism due to non-neoplastic inappropriate thyrotrophin secretion.

    OpenAIRE

    Chan, A. W.; MacFarlane, I. A.; van Heyningen, C.; Foy, P. M.

    1990-01-01

    We report a case of hyperthyroidism due to inappropriate thyrotrophin (TSH) secretion in a patient with selective pituitary resistance to thyroid hormone action. Symptoms of hyperthyroidism in patients with this disorder are usually mild, implying some peripheral tissue resistance to the metabolic effects of thyroid hormone. Our patient had unusually severe symptoms, including marked weight loss and cardiac arrythmias which required carbimazole and beta-blocker therapy for control. Somatostat...

  10. Government influence on international trade in uranium

    International Nuclear Information System (INIS)

    1978-01-01

    The subject is dealt with in sections, entitled; introduction (history of uncertainty in the uranium market, opposition to nuclear power); unsatisfactory features of today's trade conditions (including discussion of restrictions in production, exports and imports); desirable principles governing international trade in uranium, apart from the non-proliferation issue (limitation on governmental intervention for economic purposes, reservation of adequate uranium resources in exporting countries, government export price control); desirable principles for achieving balance between security of supply and non-proliferation (need for consensus, reprocessing and fast breeder reactors, principles guiding government controls established for non-proliferation purposes). (U.K.)

  11. 78 FR 78451 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Notice of Filing of...

    Science.gov (United States)

    2013-12-26

    ..., written notice to FINRA Market Operations of its intention to withdraw as a Registered Reporting ADF ECN... rejection by the ADF Trading Center. As such, an incoming order that fully posts to the book of that ADF... book of that ADF Trading Center, and is subsequently cancelled, corrected, etc., the order reporting...

  12. The political economy of services trade agreements

    OpenAIRE

    FIORINI, Matteo; LEBRAND, Mathilde

    2016-01-01

    Why do governments sign services trade agreements? This paper focuses on the role of international agreements in the context of trade in services when services are used as intermediate inputs in downstream industries. Compared to goods, services inputs are mostly non-tradable and complementary to other factors of production. We build a theoretical trade policy framework in which firms use foreign investment to contest foreign markets in services sectors and governments can restrict the entry ...

  13. 76 FR 30197 - Orange Juice From Brazil; Notice of Commission Determination To Conduct a Full Five-Year Review...

    Science.gov (United States)

    2011-05-24

    ... INTERNATIONAL TRADE COMMISSION [Investigation No. 731-TA-1089 (Review)] Orange Juice From Brazil... Orderon Orange Juice From Brazil AGENCY: United States International Trade Commission. ACTION: Notice... antidumping duty orderon orange juice from Brazil would be likely to lead to continuation or recurrence of...

  14. FINANCIAL PERFORMANCE VERSUS NON FINANCIAL PERFORMANCE. CASE STUDY AT ANTIBIOTICE TRADING COMPANY IASI

    Directory of Open Access Journals (Sweden)

    Beleneºi Mãrioara

    2012-07-01

    Full Text Available The actual economical conditions, the effect of global crisis and the efforts to pass this turning point, does force trading companies toward an extremely balanced management of performance. Now, when financial indicators are neither so spectacular nor so relevant, and when the principles of a durable development are mentioned over and over, the exigencies of companies’ external environment are higher and higher. This reality does force the companies to pay more attention to social responsibilities’ assuming and investment into green innovation, as well as to the field of information’s communication in a relevant way, which should gather financial, social and environment information. The absence of a normalized balance of financial and non-financial indicators used in measuring companies’ global performance, does allow them selecting of “agreed” indicators which should reflect the company under the light of high performance. But, the same reason urges the searcher for some research studies of the most adequate diagnostic model of global performance, which should faithfully reflect company’s current status. The purpose of this study is to measure the global performance of ANTIBIOTICE Trading Company, taking into account, both financial and non-financial indicators for a period of 5 years. For the financial years 2006 and 2008 company’s global performance is an acceptable one, while for the financial years 2007, 2009 and 2010 the global performance is a medium one. It should be highlighted the lack of involvement or transparency regarding social and environment responsibility in 2006 and weak financial performance in 2008, indicators which positioned the company to an acceptable level.

  15. 77 FR 28888 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed...

    Science.gov (United States)

    2012-05-16

    ... could disclose confidential trade secrets or commercial property such as patentable material, and... Institute of Child Health and Human Development Initial Review Group; Function, Integration, and...

  16. 75 FR 10293 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed...

    Science.gov (United States)

    2010-03-05

    ... could disclose confidential trade secrets or commercial property such as patentable material, and... Institute of Child Health and Human Development, Initial Review Group, Function, Integration, and...

  17. 76 FR 30732 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed...

    Science.gov (United States)

    2011-05-26

    ... could disclose confidential trade secrets or commercial property such as patentable material, and... Institute of Child Health and Human Development Initial Review Group; Function, Integration, and...

  18. 76 FR 9586 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed...

    Science.gov (United States)

    2011-02-18

    ... could disclose confidential trade secrets or commercial property such as patentable material, and... Institute of Child Health and Human Development Initial Review Group; Function, Integration, and...

  19. 77 FR 61418 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed...

    Science.gov (United States)

    2012-10-09

    ... could disclose confidential trade secrets or commercial property such as patentable material, and... Institute of Child Health and Human Development Initial Review Group Function, Integration, and...

  20. 76 FR 64092 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed...

    Science.gov (United States)

    2011-10-17

    ... could disclose confidential trade secrets or commercial property such as patentable material, and... Institute of Child Health and Human Development Initial Review Group, Function, Integration, and...

  1. 77 FR 12599 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed...

    Science.gov (United States)

    2012-03-01

    ... could disclose confidential trade secrets or commercial property such as patentable material, and... Institute of Child Health and Human Development Initial Review Group; Function, Integration, and...

  2. 75 FR 56118 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed...

    Science.gov (United States)

    2010-09-15

    ... could disclose confidential trade secrets or commercial property such as patentable material, and... Institute of Child Health and Human Development Initial Review Group; Function, Integration and...

  3. Transboundary Pollution, Trade Liberalization, and Environmental Taxes

    International Nuclear Information System (INIS)

    Baksi, S.; Ray Chaudhuri, A.

    2008-01-01

    In a bilateral trade framework, we examine the impact of tariff reduction on the optimal pollution tax and social welfare when pollution is transboundary. Strategic considerations lead countries to distort their pollution tax in the non-cooperative equilibrium. Trade liberalization changes the distortion, and consequently the pollution tax and welfare, in ways that depend on the extent to which pollution is transboundary. We find that when the pollution damage parameter is sufficiently small (large), bilateral tariff reduction always decreases (increases) the pollution tax, irrespective of the value of the transboundary pollution parameter. However, when the pollution damage parameter takes intermediate values, bilateral tariff reduction decreases the pollution tax if and only if the transboundary pollution parameter is sufficiently large (or even sufficiently small, in certain cases). Moreover, with pollution being transboundary, the impact of trade liberalization on welfare is non-monotonic and concave. The greater the extent to which pollution crosses borders, the more likely is trade liberalization to reduce welfare

  4. Transboundary Pollution, Trade Liberalization, and Environmental Taxes

    Energy Technology Data Exchange (ETDEWEB)

    Baksi, S. [Department of Economics, University of Winnipeg, Winnipeg (Canada); Ray Chaudhuri, A. [Department of Economics, CentER, TILEC, Tilburg University, Tilburg (Netherlands)

    2008-08-15

    In a bilateral trade framework, we examine the impact of tariff reduction on the optimal pollution tax and social welfare when pollution is transboundary. Strategic considerations lead countries to distort their pollution tax in the non-cooperative equilibrium. Trade liberalization changes the distortion, and consequently the pollution tax and welfare, in ways that depend on the extent to which pollution is transboundary. We find that when the pollution damage parameter is sufficiently small (large), bilateral tariff reduction always decreases (increases) the pollution tax, irrespective of the value of the transboundary pollution parameter. However, when the pollution damage parameter takes intermediate values, bilateral tariff reduction decreases the pollution tax if and only if the transboundary pollution parameter is sufficiently large (or even sufficiently small, in certain cases). Moreover, with pollution being transboundary, the impact of trade liberalization on welfare is non-monotonic and concave. The greater the extent to which pollution crosses borders, the more likely is trade liberalization to reduce welfare.

  5. 76 FR 42674 - Notice of Request for Approval of an Information Collection; Smuggling, Interdiction, and Trade...

    Science.gov (United States)

    2011-07-19

    ...; Smuggling, Interdiction, and Trade Compliance Program; Smuggling Form AGENCY: Animal and Plant Health... intention to initiate an information collection to support our smuggling, interdiction, and trade compliance... coming. FOR FURTHER INFORMATION CONTACT: For information on the smuggling, interdiction, and trade...

  6. 27 CFR 45.43 - Notice for smokeless tobacco.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Notice for smokeless tobacco. 45.43 Section 45.43 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY (CONTINUED) TOBACCO REMOVAL OF TOBACCO PRODUCTS AND CIGARETTE PAPERS...

  7. 78 FR 77692 - National Institute of Mental Health Notice of Meeting

    Science.gov (United States)

    2013-12-24

    ... meeting will be open to the public as indicated below, with attendance limited to space available... confidential trade secrets or commercial property such as patentable material, and personal information... Division of Intramural Research Programs. Place: National Institutes of Health (NIH), Neuroscience Center...

  8. The Transatlantic Trade and Investment Partnership (TTIP)

    OpenAIRE

    Arnim, Rudi von; Beck, Stefan; Compa, Lance; Eberhardt, Pia; Grumiller, Jan; Raza, Werner; Taylor, Lance; Tröster, Bernhard; Scherrer, Christoph

    2014-01-01

    The United States of America and the European Union are currently negotiating a Transatlantic Trade and Investment Partnership (TTIP). It is one of the most ambitious free trade and investment initiatives, going much further than eliminating tariffs. TTIP mainly aims at reducing “non-tariff barriers”. While tariffs on goods have been imposed with an eye to foreign competition, most of the non-tariff barriers are the laws and regulations that are the result of social struggles for the protecti...

  9. The Environmental Kuznets Curve: The Role of Renewable and Non-Renewable Energy Consumption and Trade Openness

    OpenAIRE

    Ben Jebli, Mehdi; Ben Youssef, Slim; Ozturk, Ilhan

    2013-01-01

    We use panel cointegration techniques to investigate the causal relationship between CO2 emissions, renewable and non-renewable energy consumption, and trade openness in three different models for a panel of twenty five OECD countries over the period 1980-2009. Also the validity of the Environmental Kuznets Curve (EKC) hypothesis has been tested for these countries. Short-run Granger causality tests show the existence of a unidirectional causality running from the square of per capita output ...

  10. Carbon trading thickness and market efficiency

    International Nuclear Information System (INIS)

    Montagnoli, Alberto; De Vries, Frans P.

    2010-01-01

    This note tests for the efficient market hypothesis (EMH) in the market for CO 2 emission allowances in Phase I and Phase II of the European Union Emissions Trading Scheme (EU ETS). As usually is the case in emerging and non-competitive markets such as the EU ETS, trading often not occurs on a frequent basis. This has adverse implications for both the gains from permit trade as well as biases the EMH tests. Variance ratio tests are employed to adjust for the thin trading effect. The results indicate that Phase I - the trial and learning period - was inefficient, whereas the first period under Phase II shows signs of restoring market efficiency. (author)

  11. TNF-α decreases VEGF secretion in highly polarized RPE cells but increases it in non-polarized RPE cells related to crosstalk between JNK and NF-κB pathways.

    Directory of Open Access Journals (Sweden)

    Hiroto Terasaki

    Full Text Available Asymmetrical secretion of vascular endothelial growth factor (VEGF by retinal pigment epithelial (RPE cells in situ is critical for maintaining the homeostasis of the retina and choroid. VEGF is also involved in the development and progression of age-related macular degeneration (AMD. We studied the effect of tumor necrosis factor-α (TNF-α on the secretion of VEGF in polarized and non-polarized RPE cells (P-RPE cells and N-RPE cells, respectively in culture and in situ in rats. A subretinal injection of TNF-α caused a decrease in VEGF expression and choroidal atrophy. Porcine RPE cells were seeded on Transwell™ filters, and their maturation and polarization were confirmed by the asymmetrical VEGF secretion and trans electrical resistance. Exposure to TNF-α decreased the VEGF secretion in P-RPE cells but increased it in N-RPE cells in culture. TNF-α inactivated JNK in P-RPE cells but activated it in N-RPE cells, and TNF-α activated NF-κB in P-RPE cells but not in N-RPE cells. Inhibition of NF-κB activated JNK in both types of RPE cells indicating crosstalk between JNK and NF-κB. TNF-α induced the inhibitory effects of NF-κB on JNK in P-RPE cells because NF-κB is continuously inactivated. In N-RPE cells, however, it was not evident because NF-κB was already activated. The basic activation pattern of JNK and NF-κB and their crosstalk led to opposing responses of RPE cells to TNF-α. These results suggest that VEGF secretion under inflammatory conditions depends on cellular polarization, and the TNF-α-induced VEGF down-regulation may result in choroidal atrophy in polarized physiological RPE cells. TNF-α-induced VEGF up-regulation may cause neovascularization by non-polarized or non-physiological RPE cells.

  12. 76 FR 48193 - Self-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing and Immediate...

    Science.gov (United States)

    2011-08-08

    ...-Regulatory Organizations; The NASDAQ Stock Market LLC; Notice of Filing and Immediate Effectiveness of Proposed Rule To Amend Fees Assessed for Use of NASDAQ Pre-Trade Risk Management August 3, 2011. Pursuant...\\ notice is hereby given that, on July 25, 2011, The NASDAQ Stock Market LLC (the ``Exchange'' or ``NASDAQ...

  13. 75 FR 32834 - U.S. Department of State Advisory Committee on Private International Law Study Group Notice of...

    Science.gov (United States)

    2010-06-09

    ... DEPARTMENT OF STATE [Public Notice 7041] U.S. Department of State Advisory Committee on Private International Law Study Group Notice of Meeting on the United Nations Commission on International Trade Law (UNCITRAL) Draft Legislative Guide on Secured Transactions and Its Treatment of Security Rights in...

  14. Optimal Time-Space Trade-Offs for Non-Comparison-Based Sorting

    DEFF Research Database (Denmark)

    Pagh, Rasmus; Pagter, Jacob Illeborg

    2002-01-01

    We study the problem of sorting n integers of w bits on a unit-cost RAM with word size w, and in particular consider the time-space trade-off (product of time and space in bits) for this problem. For comparison-based algorithms, the time-space complexity is known to be Θ(n2). A result of Beame...... shows that the lower bound also holds for non-comparison-based algorithms, but no algorithm has met this for time below the comparison-based Ω(nlgn) lower bound.We show that if sorting within some time bound &Ttilde; is possible, then time T = O(&Ttilde; + nlg* n) can be achieved with high probability...... using space S = O(n2/T + w), which is optimal. Given a deterministic priority queue using amortized time t(n) per operation and space nO(1), we provide a deterministic algorithm sorting in time T = O(n(t(n) + lg* n)) with S = O(n2/T + w). Both results require that w ≤ n1-Ω(1). Using existing priority...

  15. Assessment of Trade Policy in Terms of Export Diversification in Azerbaijan

    Directory of Open Access Journals (Sweden)

    Sevda Shakir Imamverdiyeva

    2015-09-01

    Full Text Available We analyze current status of of Azerbaijan export diversification and foreign trade policy in independent years (up from1991. The main focuse is on the tariffs and non-tariff measures of the Republic of Azerbaijan. We analyze foreign trade policy instruments of Azerbaijan one by one and compeare them with similar mechanisms of other countries. Our results show that that the foreign trade policy is very favorable for increasing foreign trade volume, and diversification of non-oil export in Azerbaijan. We find that Azerbaijan’s the maximum import tariffs level is 15%, and simple average is 9.4%. At the same time, until now Azerbaijani Government does not use most non-tariff barriers, including import quantity quotas, export subsidy, damping, anti-dumping etc.

  16. Neurotrophin Signaling Is Required for Glucose-Induced Insulin Secretion.

    Science.gov (United States)

    Houtz, Jessica; Borden, Philip; Ceasrine, Alexis; Minichiello, Liliana; Kuruvilla, Rejji

    2016-11-07

    Insulin secretion by pancreatic islet β cells is critical for glucose homeostasis, and a blunted β cell secretory response is an early deficit in type 2 diabetes. Here, we uncover a regulatory mechanism by which glucose recruits vascular-derived neurotrophins to control insulin secretion. Nerve growth factor (NGF), a classical trophic factor for nerve cells, is expressed in pancreatic vasculature while its TrkA receptor is localized to islet β cells. High glucose rapidly enhances NGF secretion and increases TrkA phosphorylation in mouse and human islets. Tissue-specific deletion of NGF or TrkA, or acute disruption of TrkA signaling, impairs glucose tolerance and insulin secretion in mice. We show that internalized TrkA receptors promote insulin granule exocytosis via F-actin reorganization. Furthermore, NGF treatment augments glucose-induced insulin secretion in human islets. These findings reveal a non-neuronal role for neurotrophins and identify a new regulatory pathway in insulin secretion that can be targeted to ameliorate β cell dysfunction. Copyright © 2016 Elsevier Inc. All rights reserved.

  17. 76 FR 20835 - Order of the Commodity Futures Trading Commission Relating to the Continuation, Shutdown, and...

    Science.gov (United States)

    2011-04-14

    ... such as system malfunctions, cyber security incidents or financial emergencies throughout a lapse in...)), part 41 (filing of notice-designated contract markets trading security futures products), regulations... (``RFA'') requires the Commission to consider whether a rule it proposes will have a significant economic...

  18. 76 FR 40733 - National Institute for Occupational Safety and Health, (NIOSH), World Trade Center Health Program...

    Science.gov (United States)

    2011-07-11

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention National Institute for Occupational Safety and Health, (NIOSH), World Trade Center Health Program Science/Technical Advisory Committee (WTCHP-STAC) Correction: This notice was published in the Federal Register on June 23...

  19. 76 FR 2941 - Bureau of Political-Military Affairs: Directorate of Defense Trade Controls; Notifications to the...

    Science.gov (United States)

    2011-01-18

    ... DEPARTMENT OF STATE [Public Notice: 7301] Bureau of Political-Military Affairs: Directorate of..., Managing Director, Directorate of Defense Trade Controls, Bureau of Political- Military Affairs, Department... services to support the design, manufacture and delivery of the Anik G1 Commercial Communication Satellite...

  20. 75 FR 49459 - Certain New Pneumatic Off-The-Road Tires from the People's Republic of China: Notice of Amended...

    Science.gov (United States)

    2010-08-13

    ... DEPARTMENT OF COMMERCE International Trade Administration A-570-912 Certain New Pneumatic Off-The-Road Tires from the People's Republic of China: Notice of Amended Final Determination of Sales at Less...: Import Administration, International Trade Administration, Department of Commerce. EFFECTIVE DATE: August...

  1. 78 FR 29375 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed...

    Science.gov (United States)

    2013-05-20

    ... could disclose confidential trade secrets or commercial property such as patentable material, and... Group; Function, Integration, and Rehabilitation Sciences Subcommittee. Date: June 3, 2013. Time: 8:30 a...

  2. 78 FR 26645 - National Institute of Mental Health; Notice of Meeting

    Science.gov (United States)

    2013-05-07

    .... The meeting will be open to the public as indicated below, with attendance limited to space available... confidential trade secrets or commercial property such as patentable material, and personal information... and discussion of NIMH program and policy issues. Place: National Institutes of Health, Neuroscience...

  3. 78 FR 22892 - National Institute of Nursing Research; Notice of Meeting

    Science.gov (United States)

    2013-04-17

    ... Research. The meeting will be open to the public as indicated below, with attendance limited to space... disclose confidential trade secrets or commercial property such as patentable material, and personal...: Discussion of Program Policies and Issues. Place: National Institutes of Health, Building 31, Conference Room...

  4. 78 FR 19724 - National Institute on Drug Abuse: Notice of Meeting

    Science.gov (United States)

    2013-04-02

    .... The meeting will be open to the public as indicated below, with attendance limited to space available... confidential trade secrets or commercial property such as patentable material, and personal information..., legislative and program developments in the drug abuse field. Place: National Institutes of Health...

  5. 78 FR 13363 - Eunice Kennedy Shriver National Institute of Child Health and Human Development; Notice of Closed...

    Science.gov (United States)

    2013-02-27

    ... could disclose confidential trade secrets or commercial property such as patentable material, and... Institute of Child Health and Human Development Initial Review Group; Function, Integration, and...

  6. Ly108 expression distinguishes subsets of invariant NKT cells that help autoantibody production and secrete IL-21 from those that secrete IL-17 in lupus prone NZB/W mice.

    Science.gov (United States)

    Tang, Xiaobin; Zhang, Bo; Jarrell, Justin A; Price, Jordan V; Dai, Hongjie; Utz, Paul J; Strober, Samuel

    2014-05-01

    Lupus is a systemic autoimmune disease characterized by anti-nuclear antibodies in humans and genetically susceptible NZB/W mice that can cause immune complex glomerulonephritis. T cells contribute to lupus pathogenesis by secreting pro-inflammatory cytokines such as IL-17, and by interacting with B cells and secreting helper factors such as IL-21 that promote production of IgG autoantibodies. In the current study, we determined whether purified NKT cells or far more numerous conventional non-NKT cells in the spleen of NZB/W female mice secrete IL-17 and/or IL-21 after TCR activation in vitro, and provide help for spontaneous IgG autoantibody production by purified splenic CD19(+) B cells. Whereas invariant NKT cells secreted large amounts of IL-17 and IL-21, and helped B cells, non-NKT cells did not. The subset of IL-17 secreting NZB/W NKT cells expressed the Ly108(lo)CD4(-)NK1.1(-) phenotype, whereas the IL-21 secreting subset expressed the Ly108(hi)CD4(+)NK1.1(-) phenotype and helped B cells secrete a variety of IgG anti-nuclear antibodies. α-galactocylceramide enhanced the helper activity of NZB/W and B6.Sle1b NKT cells for IgG autoantibody secretion by syngeneic B cells. In conclusion, different subsets of iNKT cells from mice with genetic susceptibility to lupus can contribute to pathogenesis by secreting pro-inflammatory cytokines and helping autoantibody production. Copyright © 2014 Elsevier Ltd. All rights reserved.

  7. Adrenergic influence on pentagastrin and bethanechol stimulated gastric acid secretion in dogs with gastric fistula

    DEFF Research Database (Denmark)

    Hovendal, C; Bech, K; Gottrup, F

    1984-01-01

    . The inhibitory effect of isoprenaline on pentagastrin stimulated acid secretion showed the characteristics of competitive type and on bethanechol stimulated acid secretion of non competitive type. An increasing and dose-dependent stimulation of bethanechol stimulated gastric acid secretion was found for dopamine...

  8. Search, Dealers, and the Terms of Trade

    OpenAIRE

    Gabriele Camera

    2001-01-01

    I study a search theoretic model with pairwise meetings where dealers arise endogenously. The extent of intermediation depends on its cost, trade frictions, and the dealers' ability to negociate favorable terms of trade. Under Nash bargaining, there is a unique equilibrium where dealers buy and hold the low-storage-cost good and, depending on their relative bargaining power, resell it at a premium or a discount. The distribution of the terms of trade is non-degenerate unless storage cost and ...

  9. Regulation of atrial natriuretic peptide (ANP) secretion

    International Nuclear Information System (INIS)

    Ruskoaho, H.; Toth, M.; Lang, R.E.; Unger, Th.; Garten, D.

    1986-01-01

    To investigate the role of calcium, protein kinase C and adenylate cyclase in the ANP secretion, the secretory responses from isolated perfused rat hearts to a calcium channel activator, Bay k8644 (methyl-1,4-dihydro-2,6-dimethyl-3-nitro-4-(2-trifluomethylphenyl)-2-pyridine-5-carboxylate), the calcium ionophore (A23187), the phorbol ester (12-0-tetradecanoylphorbol-13-acetate, TPA), and to forskolin were studied. ANP in perfusate was measured by radioimmunoassay 10 min before and during the infusion (30 min) of various agents at 2 min intervals. A23187 (5.7 x 10 -7 ) induced a sharp increase, whereas TPA (0.15 - 1.6 x 10 -7 ) caused a slowly progressive increase in ANP secretion. 4a-phorbol-12,13-didecanoate, a non-active phorbol ester, had no effect on ANP secretion. Bay k8644 (4 x 10 -7 ) and forskolin (1 x 10 -6 ) alone caused small but sustained increase in ANP secretion. The combination of TPA with Bay k8644, forskolin or A23187 stimulated ANP secretion higher than the calculated additive value for each agent. Dibuturyl-cAMP (1.6 x 10 -4 ) pretreatment also enhanced TPA-induced ANP release. 8-Bromo-cGMP (1.3 x 10 -4 ) and sodium nitroprusside (9 x 10 -5 ) alone had no effect, but both attenuated the TPA-induced ANP secretion. The results suggest that atrial cardiocytes possess at least two different secretory pathways for ANP secretion, which are probably dependent on protein kinase C and cyclic AMP

  10. 77 FR 26021 - National Institute of Allergy and Infectious Diseases; Notice of Closed Meeting

    Science.gov (United States)

    2012-05-02

    ... confidential trade secrets or commercial property such as patentable material, and personal information... Integration Support Contract (BISC).'' Date: May 25, 2012. Time: 8:00 a.m. to 5:00 p.m. Agenda: To review and...

  11. Streamlining digital signal processing a tricks of the trade guidebook

    CERN Document Server

    2012-01-01

    Streamlining Digital Signal Processing, Second Edition, presents recent advances in DSP that simplify or increase the computational speed of common signal processing operations and provides practical, real-world tips and tricks not covered in conventional DSP textbooks. It offers new implementations of digital filter design, spectrum analysis, signal generation, high-speed function approximation, and various other DSP functions. It provides:Great tips, tricks of the trade, secrets, practical shortcuts, and clever engineering solutions from seasoned signal processing professionalsAn assortment.

  12. On Converting Secret Sharing Scheme to Visual Secret Sharing Scheme

    Directory of Open Access Journals (Sweden)

    Wang Daoshun

    2010-01-01

    Full Text Available Abstract Traditional Secret Sharing (SS schemes reconstruct secret exactly the same as the original one but involve complex computation. Visual Secret Sharing (VSS schemes decode the secret without computation, but each share is m times as big as the original and the quality of the reconstructed secret image is reduced. Probabilistic visual secret sharing (Prob.VSS schemes for a binary image use only one subpixel to share the secret image; however the probability of white pixels in a white area is higher than that in a black area in the reconstructed secret image. SS schemes, VSS schemes, and Prob. VSS schemes have various construction methods and advantages. This paper first presents an approach to convert (transform a -SS scheme to a -VSS scheme for greyscale images. The generation of the shadow images (shares is based on Boolean XOR operation. The secret image can be reconstructed directly by performing Boolean OR operation, as in most conventional VSS schemes. Its pixel expansion is significantly smaller than that of VSS schemes. The quality of the reconstructed images, measured by average contrast, is the same as VSS schemes. Then a novel matrix-concatenation approach is used to extend the greyscale -SS scheme to a more general case of greyscale -VSS scheme.

  13. Authentication Without Secrets

    Energy Technology Data Exchange (ETDEWEB)

    Pierson, Lyndon G. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Robertson, Perry J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-11-01

    This work examines a new approach to authentication, which is the most fundamental security primitive that underpins all cyber security protections. Current Internet authentication techniques require the protection of one or more secret keys along with the integrity protection of the algorithms/computations designed to prove possession of the secret without actually revealing it. Protecting a secret requires physical barriers or encryption with yet another secret key. The reason to strive for "Authentication without Secret Keys" is that protecting secrets (even small ones only kept in a small corner of a component or device) is much harder than protecting the integrity of information that is not secret. Promising methods are examined for authentication of components, data, programs, network transactions, and/or individuals. The successful development of authentication without secret keys will enable far more tractable system security engineering for high exposure, high consequence systems by eliminating the need for brittle protection mechanisms to protect secret keys (such as are now protected in smart cards, etc.). This paper is a re-release of SAND2009-7032 with new figures numerous edits.

  14. 77 FR 59200 - National Heart, Lung, and Blood Institute; Notice of Meeting

    Science.gov (United States)

    2012-09-26

    ... space available. Individuals who plan to attend and need special assistance, such as sign language... could disclose confidential trade secrets or commercial property such as patentable material, and... program policies and issues. Place: National Institutes of Health, Building 31, 31 Center Drive...

  15. 78 FR 24761 - National Institute of Dental & Craniofacial Research; Notice of Meeting

    Science.gov (United States)

    2013-04-26

    ... limited to space available. Individuals who plan to attend and need special assistance, such as sign... and the discussions could disclose confidential trade secrets or commercial property such as... available. (Catalogue of Federal Domestic Assistance Program Nos. 93.121, Oral Diseases and Disorders...

  16. 77 FR 74674 - National Institute of Dental & Craniofacial Research; Notice of Meeting

    Science.gov (United States)

    2012-12-17

    ... limited to space available. Individuals who plan to attend and need special assistance, such as sign... and the discussions could disclose confidential trade secrets or commercial property such as... professional affiliation of the interested person. (Catalogue of Federal Domestic Assistance Program Nos. 93...

  17. 77 FR 74198 - National Institute Environmental Health Sciences Notice of Meeting

    Science.gov (United States)

    2012-12-13

    ... attendance limited to space available. Individuals who plan to attend and need special assistance, such as... applications and the discussions could disclose confidential trade secrets or commercial property such as.... to 4:35 p.m. Agenda: Discussion of program policies and issues. Place: Nat. Inst. of Environmental...

  18. 76 FR 571 - National Institute of Nursing Research; Notice of Meeting

    Science.gov (United States)

    2011-01-05

    ... Research. The meeting will be open to the public as indicated below, with attendance limited to space... disclose confidential trade secrets or commercial property such as patentable material, and personal...: Discussion of Program Policies and Issues. Place: National Institutes of Health, Building 31, 31 Center Drive...

  19. Understanding Canada's International Trade Policy. "Understanding Economics" Series No. 4.

    Science.gov (United States)

    Cornell, Peter M.

    Written for secondary school Canadian students, the document examines Canada's international trade policy. It is arranged in three sections. Part I discusses the affect of Canada's trade policy on the individual citizen. Tariffs and non-tariff barriers to trade such as import licenses, preferential purchasing agreements, health and safety…

  20. Cultural distance and international trade: a non-linear relationship

    NARCIS (Netherlands)

    Lankhuizen, M.B.M.; de Groot, H.L.F.

    2016-01-01

    This paper investigates the effect of culture on trade using measures of cultural distance based on various dimensions of national culture from Hofstede (Culture’s Consequences: International Differences in Work-Related Values, 1980; Culture’s Consequences: Comparing Values, Behaviors, Institutions

  1. Penerapan Prinsip Non Discrimination Dalam World Trade Organization Terhadap Kebijakan Tenaga Kerja Asing Di Indonesia (Studi Kasus : Tenaga Kerja Asing Tiongkok Di Indonesia)

    OpenAIRE

    -, VERA NURUL HAYATI

    2016-01-01

    2016 Vera Nurul Hayati (B 111 12 117),The Application of Non Discrimination Principle of World Trade Organization Against Foreign Workers in Indonesia (Case Study : China Foreign Workers in Indonesia), led by Muhammad Ashri dan Laode Abdul Gani. Writing aims to determine 1) Implementation of Non Discrimination principle on policy regulation against Foreign labor in Indonesia. 2) Enforcement of non discrimination principle against Tiongkok foreign labor in Indonesia. ...

  2. Emission Trading under the Kyoto Protocol

    Energy Technology Data Exchange (ETDEWEB)

    Holtsmark, Bjart; Hagem, Cathrine

    1998-12-01

    This report discusses the potential gains from emission trading and raises some crucial questions. It shows that the total costs of the Kyoto Protocol could be reduced by about 95% through emission trading. Emission trading is an option also in the domestic arenas. The governments of the Annex B countries may allocate emission quotas to local enterprises as emission permits. Thus new markets for greenhouse gas emission quotas may emerge, domestically and internationally. It is emphasized that emission trading at the national and international levels must be discussed separately. The Nordic governments, for example, will find several good reasons for supporting emission trading at the international level if not necessarily domestically. The Nordic countries have already implemented domestic taxes on CO{sub 2} emissions and this tax policy could be sustained while these governments support and take part in emission trading at the international level.The report also considers a possible side effect of emission trading: free emission trading among Annex B countries could reduce the total abatement compared to a non-tradable policy as a consequence of the fact that some of the countries that are in transition to a market economy may be given emission limitations above their business-as-usual emissions. 40 refs., 7 figs., 4 tabs.

  3. 75 FR 13614 - Self-Regulatory Organizations; NASDAQ OMX PHLX, Inc.; Notice of Filing of Proposed Rule Change To...

    Science.gov (United States)

    2010-03-22

    ... to handle the additional traffic associated with the listing and trading of $1 strikes where the...-Regulatory Organizations; NASDAQ OMX PHLX, Inc.; Notice of Filing of Proposed Rule Change To Establish Strike... 1012 (Series of Options Open for Trading) to establish strike-price intervals for options on Index...

  4. 27 CFR 40.216a - Notice for pipe tobacco.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Notice for pipe tobacco. 40.216a Section 40.216a Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY (CONTINUED) TOBACCO MANUFACTURE OF TOBACCO PRODUCTS, CIGARETTE PAPERS...

  5. 75 FR 16211 - MCG Capital Corporation; Notice of Application

    Science.gov (United States)

    2010-03-31

    ... SECURITIES AND EXCHANGE COMMISSION [Investment Company Act Release No. 29191; File No. 812-13694] MCG Capital Corporation; Notice of Application March 25, 2010. AGENCY: Securities and Exchange... exchange on which its shares of common stock may be traded in the future) as of the date of the transaction...

  6. Insulin secretion and insulin action in non-insulin-dependent diabetes mellitus: which defect is primary?

    Science.gov (United States)

    Reaven, G M

    1984-01-01

    Defects in both insulin secretion and insulin action exist in patients with non-insulin-dependent diabetes mellitus (NIDDM). The loss of the acute plasma insulin response to intravenous glucose is seen in patients with relatively mild degrees of fasting hyperglycemia, but patients with severe fasting hyperglycemia also demonstrate absolute hypoinsulinemia in response to an oral glucose challenge. In contrast, day-long circulating insulin levels are within normal limits even in severely hyperglycemic patients with NIDDM. The relationship between NIDDM and insulin action in NIDDM is less complex, and is a characteristic feature of the syndrome. This metabolic defect is independent of obesity, and the severity of the resistance to insulin-stimulated glucose uptake increases with magnitude of hyperglycemia. Control of hyperglycemia with exogenous insulin ameliorates the degree of insulin resistance, and reduction of insulin resistance with weight loss in obese patients with NIDDM leads to an enhanced insulin response. Since neither therapeutic intervention is capable of restoring all metabolic abnormalities to normal, these observations do not tell us which of these two defects is primarily responsible for the development of NIDDM. Similarly, the observation that most patients with impaired glucose tolerance are hyperinsulinemic and insulin resistant does not prove that insulin resistance is the primary defect in NIDDM. In conclusion, reduction in both insulin secretion and action is seen in patients with NIDDM, and the relationship between these two metabolic abnormalities is very complex.(ABSTRACT TRUNCATED AT 250 WORDS)

  7. 75 FR 28845 - Self-Regulatory Organizations; National Stock Exchange, Inc.; Notice of Filing of a Proposed Rule...

    Science.gov (United States)

    2010-05-24

    ... the Exchange is the primary listing market if the price of such security moves 10% or more from a sale... the last consolidated sale price of a Listed Circuit Breaker Security (``Trigger Trade'') to a... Organizations; National Stock Exchange, Inc.; Notice of Filing of a Proposed Rule Change To Establish a Trading...

  8. Combined contributions of over-secreted glucagon-like peptide 1 and suppressed insulin secretion to hyperglycemia induced by gatifloxacin in rats

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Yunli, E-mail: chrisyu1255@yahoo.com.cn [Department of Pharmaceutics, The Second Affiliated Hospital of Soochow University, Suzhou 215004 (China); Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009 (China); Wang, Xinting, E-mail: wxinting1986@yahoo.com.cn [Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009 (China); Liu, Can, E-mail: ltsan@163.com [Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009 (China); Yao, Dan, E-mail: erinyao@126.com [Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009 (China); Shanghai Institute of Materia Medica, Shanghai 201203 (China); Hu, Mengyue, E-mail: juliahmy@126.com [Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009 (China); Li, Jia, E-mail: ljbzd@163.com [Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009 (China); Hu, Nan, E-mail: hn_324@163.com [Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009 (China); Liu, Li, E-mail: liulee@cpu.edu.cn [Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009 (China); Liu, Xiaodong, E-mail: xdliu@cpu.edu.cn [Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing 210009 (China)

    2013-02-01

    Accumulating evidences have showed that gatifloxacin causes dysglycemia in both diabetic and non-diabetic patients. Our preliminary study demonstrated that gatifloxacin stimulated glucagon-like peptide 1 (GLP-1) secretion from intestinal cells. The aim of the study was to investigate the association between gatifloxacin-stimulated GLP-1 release and dysglycemia in both normal and streptozotocin-induced diabetic rats and explore the possible mechanisms. Oral administration of gatifloxacin (100 mg/kg/day and 200 mg/kg/day) for 3 and 12 days led to marked elevation of GLP-1 levels, accompanied by significant decrease in insulin levels and increase in plasma glucose. Similar results were found in normal rats treated with 3-day gatifloxacin. Gatifloxacin-stimulated GLP-1 release was further confirmed in NCI-H716 cells, which was abolished by diazoxide, a K{sub ATP} channel opener. QT-PCR analysis showed that gatifloxacin also upregulated expression of proglucagon and prohormone convertase 3 mRNA. To clarify the contradiction on elevated GLP-1 without insulinotropic effect, effects of GLP-1 and gatifloxacin on insulin release were investigated using INS-1 cells. We found that short exposure (2 h) to GLP-1 stimulated insulin secretion and biosynthesis, whereas long exposure (24 h and 48 h) to high level of GLP-1 inhibited insulin secretion and biosynthesis. Moreover, we also confirmed gatifloxacin acutely stimulated insulin secretion while chronically inhibited insulin biosynthesis. All the results gave an inference that gatifloxacin stimulated over-secretion of GLP-1, in turn, high levels of GLP-1 and gatifloxacin synergistically impaired insulin release, worsening hyperglycemia. -- Highlights: ► Gatifloxacin induced hyperglycemia both in diabetic rats and normal rats. ► Gatifloxacin enhanced GLP-1 secretion but inhibited insulin secretion in rats. ► Long-term exposure to high GLP-1 inhibited insulin secretion and biosynthesis. ► GLP-1 over-secretion may be

  9. Combined contributions of over-secreted glucagon-like peptide 1 and suppressed insulin secretion to hyperglycemia induced by gatifloxacin in rats

    International Nuclear Information System (INIS)

    Yu, Yunli; Wang, Xinting; Liu, Can; Yao, Dan; Hu, Mengyue; Li, Jia; Hu, Nan; Liu, Li; Liu, Xiaodong

    2013-01-01

    Accumulating evidences have showed that gatifloxacin causes dysglycemia in both diabetic and non-diabetic patients. Our preliminary study demonstrated that gatifloxacin stimulated glucagon-like peptide 1 (GLP-1) secretion from intestinal cells. The aim of the study was to investigate the association between gatifloxacin-stimulated GLP-1 release and dysglycemia in both normal and streptozotocin-induced diabetic rats and explore the possible mechanisms. Oral administration of gatifloxacin (100 mg/kg/day and 200 mg/kg/day) for 3 and 12 days led to marked elevation of GLP-1 levels, accompanied by significant decrease in insulin levels and increase in plasma glucose. Similar results were found in normal rats treated with 3-day gatifloxacin. Gatifloxacin-stimulated GLP-1 release was further confirmed in NCI-H716 cells, which was abolished by diazoxide, a K ATP channel opener. QT-PCR analysis showed that gatifloxacin also upregulated expression of proglucagon and prohormone convertase 3 mRNA. To clarify the contradiction on elevated GLP-1 without insulinotropic effect, effects of GLP-1 and gatifloxacin on insulin release were investigated using INS-1 cells. We found that short exposure (2 h) to GLP-1 stimulated insulin secretion and biosynthesis, whereas long exposure (24 h and 48 h) to high level of GLP-1 inhibited insulin secretion and biosynthesis. Moreover, we also confirmed gatifloxacin acutely stimulated insulin secretion while chronically inhibited insulin biosynthesis. All the results gave an inference that gatifloxacin stimulated over-secretion of GLP-1, in turn, high levels of GLP-1 and gatifloxacin synergistically impaired insulin release, worsening hyperglycemia. -- Highlights: ► Gatifloxacin induced hyperglycemia both in diabetic rats and normal rats. ► Gatifloxacin enhanced GLP-1 secretion but inhibited insulin secretion in rats. ► Long-term exposure to high GLP-1 inhibited insulin secretion and biosynthesis. ► GLP-1 over-secretion may be involved in

  10. A FRAMEWORK FOR TRANSPARENCY IN INTERNATIONAL TRADE

    Directory of Open Access Journals (Sweden)

    Bernal Turnes, Paloma

    2015-01-01

    Full Text Available The aim of this paper is to cover the gap in literature about transparency in the context of international trade facilitation. It focuses on the importance of transparency in achieving growth in international trade and the differences between non-transparent practices and corruption in global trade. Managing the disclosure of information about rules, regulations and laws is not the only trade policy instrument where transparency becomes important. To build a framework on levels of transparency we developed a matrix classifying the transparency of each country based on ease of doing business and levels of bribery. Four different strategies are explained based on the different scenarios of transparency in international trade. The main conclusions reflect that disclosure of information is not enough to guarantee transparency and monitoring of transparency must be improved.

  11. Insulin and C-peptide secretion in non-obese patients with polycystic ovarian disease.

    Science.gov (United States)

    Mahabeer, S; Jialal, I; Norman, R J; Naidoo, C; Reddi, K; Joubert, S M

    1989-09-01

    Plasma glucose, immunoreactive insulin (IRI) and C-peptide responses during an oral glucose tolerance test (oGTT) were assessed in 11 non-obese patients with polycystic ovarian disease (PCOD) and 11 reference subjects matched for age, height and weight. Also, 6 patients with PCOD and 6 normal women were subjected to intravenous glucose tolerance testing (ivGTT) On oGTT, all subjects exhibited normal glucose tolerance; however, PCOD patients had significantly higher mean plasma glucose levels at 30, 60, 90 and 120 min and higher mean incremental glucose areas. In addition the patients with polycystic ovaries showed higher mean basal IRI and C-peptide levels, higher mean glucose stimulated IRI and C-peptide levels and higher mean incremental IRI and C-peptide values. The molar ratios of C-peptide/IRI were significantly lower in the PCOD group at all time intervals after glucose stimulation when compared to the normal women. During ivGTT, there were significantly higher mean glucose levels at 5, 40, 50 and 60 min in the PCOD group when compared to the reference group. The IRI response to intravenous glucose in the PCOD women was similar to the reference group. The findings on oGTT suggest that non-obese patients with PCOD have increased pancreatic IRI secretion as well as impaired hepatic extraction of the hormone.

  12. 77 FR 72872 - National Institute of Neurological Disorders and Stroke; Notice of Meeting

    Science.gov (United States)

    2012-12-06

    ... limited to space available. Individuals who plan to attend and need special assistance, such as sign... and the discussions could disclose confidential trade secrets or commercial property such as... Associate Director for Extramural Research; and Administrative and Program Developments. Place: National...

  13. 78 FR 76633 - National Institute of Neurological Disorders and Stroke; Notice of Meeting

    Science.gov (United States)

    2013-12-18

    ... limited to space available. Individuals who plan to attend and need special assistance, such as sign... and the discussions could disclose confidential trade secrets or commercial property such as... Director for Extramural Research; and Administrative and Program Developments. Place: National Institutes...

  14. Proteomic analysis of rutin-induced secreted proteins from Aspergillus flavus.

    Science.gov (United States)

    Medina, Martha L; Kiernan, Urban A; Francisco, Wilson A

    2004-03-01

    Few studies have been conducted to identify the extracellular proteins and enzymes secreted by filamentous fungi, particularly with respect to dispensable metabolic pathways. Proteomic analysis has proven to be the most powerful method for identification of proteins in complex mixtures and is suitable for the study of the alteration of protein expression under different environmental conditions. The filamentous fungus Aspergillus flavus can degrade the flavonoid rutin as the only source of carbon via an extracellular enzyme system. In this study, a proteomic analysis was used to differentiate and identify the extracellular rutin-induced and non-induced proteins secreted by A. flavus. The secreted proteins were analyzed by two-dimensional electrophoresis and MALDI-TOF mass spectrometry. While 15 rutin-induced proteins and 7 non-induced proteins were identified, more than 90 protein spots remain unidentified, indicating that these proteins are either novel proteins or proteins that have not yet been sequenced.

  15. 78 FR 77472 - National Institute of General Medical Sciences; Notice of Meeting

    Science.gov (United States)

    2013-12-23

    ... comment period at the end. Attendance is limited by the space available. Individuals who plan to attend... disclose confidential trade secrets or commercial property, such as patentable material, and personal... Adjournment. Agenda: For the discussion of program policies and issues, opening remarks, report of the...

  16. 78 FR 50069 - National Center for Advancing Translational Sciences; Notice of Meetings

    Science.gov (United States)

    2013-08-16

    ... attendance limited to space available. Individuals who plan to attend and need special assistance, such as... applications and the discussions could disclose confidential trade secrets or commercial property such as...-8064, [email protected] . Dated: August 8, 2013. Michelle Trout, Program Analyst, Office of Federal...

  17. 76 FR 23612 - National Institute of Dental & Craniofacial Research; Notice of Meeting

    Science.gov (United States)

    2011-04-27

    ... limited to space available. Individuals who plan to attend and need special assistance, such as sign... and the discussions could disclose confidential trade secrets or commercial property such as... posted when available. (Catalogue of Federal Domestic Assistance Program Nos. 93.121, Oral Diseases and...

  18. 77 FR 75180 - National Center for Advancing Translational Sciences; Notice of Meeting

    Science.gov (United States)

    2012-12-19

    ..., with attendance limited to space available. Individuals who plan to attend and need special assistance... applications and the discussions could disclose confidential trade secrets or commercial property such as...: December 12, 2012. David Clary, Program Analyst, Office of Federal Advisory Committee Policy. [FR Doc. 2012...

  19. 77 FR 23488 - National Institute of Dental & Craniofacial Research; Notice of Meeting

    Science.gov (United States)

    2012-04-19

    ... limited to space available. Individuals who plan to attend and need special assistance, such as sign... and/or contract proposals and the discussions could disclose confidential trade secrets or commercial... Federal Domestic Assistance Program Nos. 93.121, Oral Diseases and Disorders Research, National Institutes...

  20. 76 FR 80953 - National Institute of Dental & Craniofacial Research; Notice of Meeting

    Science.gov (United States)

    2011-12-27

    ... limited to space available. Individuals who plan to attend and need special assistance, such as sign... and/or contract proposals and the discussions could disclose confidential trade secrets or commercial... Federal Domestic Assistance Program Nos. 93.121, Oral Diseases and Disorders Research, National Institutes...

  1. 78 FR 76634 - National Center for Advancing Translational Sciences; Notice of Meetings

    Science.gov (United States)

    2013-12-18

    ... attendance limited to space available. Individuals who plan to attend and need special assistance, such as... applications and the discussions could disclose confidential trade secrets or commercial property such as... 20892, 301-594-8064, [email protected] . Dated: December 12, 2013. David Clary, Program Analyst...

  2. 78 FR 47715 - National Human Genome Research Institute; Notice of Meeting

    Science.gov (United States)

    2013-08-06

    ... space available. Individuals who plan to attend and need special assistance, such as sign language... could disclose confidential trade secrets or commercial property such as patentable material, and...: September 09, 2013, 10:00 a.m. to 4:00 p.m. Agenda: To discuss matters of program relevance. Place: National...

  3. 75 FR 28831 - Self-Regulatory Organizations; New York Stock Exchange LLC; Notice of Filing of a Proposed Rule...

    Science.gov (United States)

    2010-05-24

    ... second by comparing each last consolidated sale price of a security (``Trigger Trade'') during the...-Regulatory Organizations; New York Stock Exchange LLC; Notice of Filing of a Proposed Rule Change Adding Rule 80C To Provide for a Trading Pause for Individual Securities When the Price Moves 10 Percent or More...

  4. Trade-Off Analysis between Concerns Based on Aspect-Oriented Requirements Engineering

    Science.gov (United States)

    Laurito, Abelyn Methanie R.; Takada, Shingo

    The identification of functional and non-functional concerns is an important activity during requirements analysis. However, there may be conflicts between the identified concerns, and they must be discovered and resolved through trade-off analysis. Aspect-Oriented Requirements Engineering (AORE) has trade-off analysis as one of its goals, but most AORE approaches do not actually offer support for trade-off analysis; they focus on describing concerns and generating their composition. This paper proposes an approach for trade-off analysis based on AORE using use cases and the Requirements Conflict Matrix (RCM) to represent compositions. RCM shows the positive or negative effect of non-functional concerns over use cases and other non-functional concerns. Our approach is implemented within a tool called E-UCEd (Extended Use Case Editor). We also show the results of evaluating our tool.

  5. 27 CFR 41.72a - Notice for pipe tobacco.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Notice for pipe tobacco. 41.72a Section 41.72a Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY (CONTINUED) TOBACCO IMPORTATION OF TOBACCO PRODUCTS, CIGARETTE PAPERS AND TUBES...

  6. 75 FR 44761 - Export Trade Certificate of Review

    Science.gov (United States)

    2010-07-29

    ... sales prices and/or minimum target sales prices, and other terms of sales in the Export Markets... canned salmon in the Export Markets, selling strategies for the Export Markets, sales for the Export... described below for the following Export Trade and Export Markets: Export Trade Products Shelf stable non...

  7. 26 CFR 1.923-1T - Temporary regulations; exempt foreign trade income.

    Science.gov (United States)

    2010-04-01

    ... be exempt foreign trade income. If a FSC has a non-corporate shareholder (shareholders), 16/23 of its foreign trade income attributable to the noncorporate shareholder's (shareholders') proportionate interest... attributable to the non-corporate shareholder's (shareholders') proportionate interest in the FSC will be...

  8. 78 FR 22274 - National Institute of Neurological Disorders and Stroke; Notice of Meeting

    Science.gov (United States)

    2013-04-15

    ... limited to space available. Individuals who plan to attend and need special assistance, such as sign... and the discussions could disclose confidential trade secrets or commercial property such as... for Extramural Research; Administrative and Program Developments; and an Overview of the NINDS...

  9. 78 FR 51734 - National Center for Complementary and Alternative Medicine Notice of Meeting

    Science.gov (United States)

    2013-08-21

    ... below, with attendance limited to space available. Individuals who plan to attend and need special.... The grant applications and the discussions could disclose confidential trade secrets or commercial... for the meeting will be posted when available. (Catalogue of Federal Domestic Assistance Program Nos...

  10. 78 FR 53004 - Requested Administrative Waiver of the Coastwise Trade Laws: Vessel SECOND WIND; Invitation for...

    Science.gov (United States)

    2013-08-27

    ... Administrative Waiver of the Coastwise Trade Laws: Vessel SECOND WIND; Invitation for Public Comments AGENCY... SECOND WIND is: Intended Commercial Use of Vessel: ``Breakfast, lunch, and dinner cruises featuring... to the docket number of this notice and the vessel name in order for MARAD to properly consider the...

  11. Anonymous electronic trading versus floor trading

    OpenAIRE

    Franke, Günter; Hess, Dieter

    1995-01-01

    This paper compares the attractiveness of floor trading and anonymous electronic trading systems. It is argued that in times of low information intensity the insight into the order book of the electronic trading system provides more valuable information than floor trading, but in times of high information intensity the reverse is true. Thus, the electronic system's market share in trading activity should decline in times of high information intensity. This hypothesis is tested by data on BUND...

  12. 77 FR 76059 - National Institute of General Medical Sciences; Notice of Meeting

    Science.gov (United States)

    2012-12-26

    ... limited to space available. Individuals who plan to attend and need special assistance, such as sign... and the discussions could disclose confidential trade secrets or commercial property such as...: January 25, 2013, 8:30 a.m. to Adjournment. Agenda: For the discussion of program policies and issues...

  13. 78 FR 25281 - National Institute of General Medical Sciences; Notice of Meeting

    Science.gov (United States)

    2013-04-30

    ... limited to space available. Individuals who plan to attend and need special assistance, such as sign... and the discussions could disclose confidential trade secrets or commercial property, such as... 17, 2013, 8:30 a.m. to ADJOURNMENT. Agenda: For the discussion of program policies and issues...

  14. 78 FR 48695 - National Institute of Environmental Health Sciences; Notice of Meeting

    Science.gov (United States)

    2013-08-09

    ... attendance limited to space available. Individuals who plan to attend and need special assistance, such as... applications and the discussions could disclose confidential trade secrets or commercial property such as.... to 3:15 p.m. Agenda: Discussion of program policies and issues. Place: Nat. Inst. of Environmental...

  15. New Commitment Options: Compatibility with Emissions Trading

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    This paper considers different options for quantitative greenhouse gas emission commitments from the standpoint of their technical compatibility with emissions trading. These are dynamic targets, binding targets with price caps, non-binding targets, sector-wide targets/mechanisms, action targets, allowances and endowments, and long-term permits. This paper considers these options from the standpoint of their compatibility with emissions trading.

  16. 78 FR 50067 - National Institute of Nursing Research; Notice of Meeting

    Science.gov (United States)

    2013-08-16

    ... Research. The meeting will be open to the public as indicated below, with attendance limited to space... and the discussions could disclose confidential trade secrets or commercial property such as..., 2013. Open: September 17, 2013, 1:00 p.m. to 5:15 p.m. Agenda: Discussion of Program Policies and...

  17. 75 FR 46951 - National Human Genome Research Institute; Notice of Meeting

    Science.gov (United States)

    2010-08-04

    ... space available. Individuals who plan to attend and need special assistance, such as sign language... proposals and the discussions could disclose confidential trade secrets or commercial property such as... 13-14, 2010. Open: September 13, 2010, 8:30 a.m. to 3 p.m. Agenda: To discuss matters of program...

  18. 78 FR 75358 - National Institute of Nursing Research; Notice of Meeting

    Science.gov (United States)

    2013-12-11

    ... Research. The meeting will be open to the public as indicated below, with attendance limited to space... and the discussions could disclose confidential trade secrets or commercial property such as..., 2014. Open: January 13, 2014, 1:00 p.m. to 5:00 p.m. Agenda: Discussion of Program Policies and Issues...

  19. Fundamental rate-loss trade-off for the quantum internet.

    Science.gov (United States)

    Azuma, Koji; Mizutani, Akihiro; Lo, Hoi-Kwong

    2016-11-25

    The quantum internet holds promise for achieving quantum communication-such as quantum teleportation and quantum key distribution (QKD)-freely between any clients all over the globe, as well as for the simulation of the evolution of quantum many-body systems. The most primitive function of the quantum internet is to provide quantum entanglement or a secret key to two points efficiently, by using intermediate nodes connected by optical channels with each other. Here we derive a fundamental rate-loss trade-off for a quantum internet protocol, by generalizing the Takeoka-Guha-Wilde bound to be applicable to any network topology. This trade-off has essentially no scaling gap with the quantum communication efficiencies of protocols known to be indispensable to long-distance quantum communication, such as intercity QKD and quantum repeaters. Our result-putting a practical but general limitation on the quantum internet-enables us to grasp the potential of the future quantum internet.

  20. 27 CFR 45.45a - Notice for pipe tobacco.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Notice for pipe tobacco. 45.45a Section 45.45a Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY (CONTINUED) TOBACCO REMOVAL OF TOBACCO PRODUCTS AND CIGARETTE PAPERS AND TUBES...

  1. 78 FR 5467 - National Institute of Allergy and Infectious Diseases; Notice of Closed Meeting

    Science.gov (United States)

    2013-01-25

    ... confidential trade secrets or commercial property such as patentable material, and personal information... Infectious Diseases Special Emphasis Panel; ``OMICS'' Technologies for Predictive Modeling of Infectious... applications. Place: Sheraton Silver Spring Hotel, 8777 Georgia Avenue, Silver Spring, MD 20910. Contact Person...

  2. 77 FR 31034 - Notice of Realty Action: Non-Competitive Direct Sale of Reversionary Interest Recreation and...

    Science.gov (United States)

    2012-05-24

    ...-08807; MO 4500030924; TAS: 14X5232] Notice of Realty Action: Non-Competitive Direct Sale of Reversionary... check, U.S. postal money order, or bank draft, and made payable in U.S. dollars to the ``Department of... percent deposit. Payment must be submitted in the form of a certified check, U.S. postal money order, bank...

  3. 27 CFR 19.824 - Notice of permanent discontinuance of business.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Notice of permanent discontinuance of business. 19.824 Section 19.824 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS DISTILLED SPIRITS PLANTS Production of Vinegar by...

  4. trade on non-timber forest products (ntfps) between south west ...

    African Journals Online (AJOL)

    DJFLEX

    KEY WORDS: NTFPs, Trade, Trans-boundary, Ejagham, Forest Reserve. INTRODUCTION .... Table 1: Identified NTFPs, sources and relative abundance in the Study Area. Common Names ..... The role of research for a balance between.

  5. FORMAL TRADE BETWEEN INDIA AND BANGLADESH: AN EMPIRICAL ANALYSIS

    Directory of Open Access Journals (Sweden)

    S. K.S. YADAV

    2016-08-01

    Full Text Available The importance of improving trade flows between India and Bangladesh is not only beneficial to them, but for the whole SAARC region, given that Bhutan and Nepal utilise Bangladesh ports as gateways to trade outside the region. Bangladesh’s overall exports are dominated by labour-intensive manufacturing and its imports to India by primary commodities. The shares of manufactured goods in country’s overall export were about 92 and 91 percent in 2001 and 2011 respectively. However, the composition of bilateral trade between these two countries has been changing over time. Addition and removal in the list of products of trade basket is a usual process. Consistent products in the trade basket of Bangladesh are ready made garments and sea food, whereas those of India are raw cotton, cereals and products and machinery of iron and steel. Expansion of trade of these countries with outside world, but not with each other confirms the prevalence of certain barriers, physical or non-physical in nature, rendering many potential products remain untraded. India and Bangladesh being geographically proximate to each other possess huge scope to trade. Specifically as both the countries are rich in natural resources and are competent in the production of small-scale manufacturing and agrarian supplies, mostly from the eastern parts of India and Bangladesh, both possess huge potential for bilateral trade. Many items having high trade potential are still not able to get market exposure in the neighbouring country because of various non-tariff barriers prevailing in current trade scenario, which have hiked up the cost of doing business to unacceptable proportions and as most of the highly tradable products are still kept under the sensitive lists of Bangladesh. There are numerous bottlenecks in the current trade infrastructure which turns out to be physical barrier to trade. The present paper highlights the import export and Exchange Rate change and prospects of

  6. Reassessing the Evolution of World Trade, 1870-1949

    OpenAIRE

    Milionis, Petros; Klasing, Mariko J.

    2012-01-01

    The typical narrative regarding the evolution of world trade prior to World War II refers to a secular rise that started around 1870 and a subsequent collapse that began in 1914. This narrative, though, is based on measures of trade openness that do not fully take into account purchasing power differences across countries, as in the literature non-PPP-adjusted trade data are typically denominated by PPP-adjusted GDP data. The present paper seeks to resolve this inconsistency by constructing n...

  7. 17 CFR 160.6 - Information to be included in privacy notices.

    Science.gov (United States)

    2010-04-01

    ... future to disclose, but to whom you do not currently disclose, nonpublic personal information. (f) Model... privacy notices. 160.6 Section 160.6 Commodity and Securities Exchanges COMMODITY FUTURES TRADING... that you make disclosures to other nonaffiliated companies: (1) For your everyday business purposes...

  8. 78 FR 13897 - Bureau of International Labor Affairs; Office of Trade and Labor Affairs; Labor Affairs Council...

    Science.gov (United States)

    2013-03-01

    ... Public Session Meeting AGENCY: International Labor Affairs Bureau (ILAB), U.S. Department of Labor.... Department of Labor gives notice of the public session of the meeting of the Labor Affairs Council (``Council... DEPARTMENT OF LABOR Office of the Secretary Bureau of International Labor Affairs; Office of Trade...

  9. Exchange Rate Volatility and Trade among the Asia Pacific Countries

    Directory of Open Access Journals (Sweden)

    Saang Joon Baak

    2004-06-01

    Full Text Available The purpose of this paper is to investigate the impact of exchange rate volatility on exports among 14 Asia Pacific countries, where various measures to raise the intra-region trade are being implemented. Specifically, this paper estimates a gravity model, in which the dependent variable is the product of the exports of two trading countries. In addition, it also estimates a unilateral exports model, in which the dependent variable is not the product of the exports of two trading countries but the exports from one country to another. By doing this, the depreciation rate of the exporting country's currency value can be included as one of the explanatory variables affecting the volume of exports. As the explanatory variables of the export volume, the gravity model adopts the product of the GDPs of two trading counties, their bilateral exchange rate volatility, their distance, a time trend and dummies for the share of the border line, the use of the same language, and the APEC membership. In the case of the unilateral exports model, the product of the GDPs is replaced by the GDP of the importing country, and the depreciation rate of the exporting country's currency value is dded. In addition, considering that the export volume will also depend on various onditions of the exporting country, dummies for exporting countries are also included as an explanatory variable. The empirical tests, using annual data for the period from 1980 to 2002, detect a significant negative impact of exchange rate volatility on the volume of exports. In addition, various tests using the data for sub-sample periods indicate that the negative impact had been weakened since 1989, when APEC had launched, and surged again from 1997, when the Asian financial crisis broke out. This finding implies that the impact of exchange rate volatility is time-dependent and that it is significantlynegative at least in the present time. This phenomenon is noticed regardless which estimation

  10. 77 FR 38351 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change To List...

    Science.gov (United States)

    2012-06-27

    ... copper market is the third largest metals market in terms of physical volume. Much of the copper traded...-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change To List and Trade Shares of iShares Copper Trust Pursuant to NYSE Arca Equities Rule 8.201 June 22, 2012. Pursuant to Section...

  11. 76 FR 78015 - National Institute on Alcohol Abuse and Alcoholism; Notice of Meeting

    Science.gov (United States)

    2011-12-15

    ... attendance limited to space available. Individuals who plan to attend and need special assistance, such as... applications and the discussions could disclose confidential trade secrets or commercial property such as... . (Catalogue of Federal Domestic Assistance Program Nos. 93.271, Alcohol Research Career Development Awards for...

  12. 75 FR 2149 - National Institute of Neurological Disorders and Stroke; Notice of Meeting

    Science.gov (United States)

    2010-01-14

    ... attendance limited to space available. Individuals who plan to attend and need special assistance, such as... applications and/or contract proposals and the discussions could disclose confidential trade secrets or... for the meeting will be posted when available. (Catalogue of Federal Domestic Assistance Program Nos...

  13. 76 FR 39406 - National Institute on Alcohol Abuse and Alcoholism; Notice of Meeting

    Science.gov (United States)

    2011-07-06

    ... attendance limited to space available. Individuals who plan to attend and need special assistance, such as... applications and the discussions could disclose confidential trade secrets or commercial property such as.... (Catalogue of Federal Domestic Assistance Program Nos. 93.271, Alcohol Research Career Development Awards for...

  14. 77 FR 24726 - National Institute on Alcohol Abuse and Alcoholism; Notice of Meeting

    Science.gov (United States)

    2012-04-25

    ... attendance limited to space available. Individuals who plan to attend and need special assistance, such as... applications and the discussions could disclose confidential trade secrets or commercial property such as... Assistance Program Nos. 93.273, Alcohol Research Programs; 93.701, ARRA Related Biomedical Research and...

  15. 75 FR 52010 - National Institute of Neurological Disorders and Stroke; Notice of Meetings

    Science.gov (United States)

    2010-08-24

    ... attendance limited to space available. Individuals who plan to attend and need special assistance, such as... applications and the discussions could disclose confidential trade secrets or commercial property such as... Domestic Assistance Program Nos. 93.853, Clinical Research Related to Neurological Disorders; 93.854...

  16. 77 FR 43604 - National Institute on Alcohol Abuse and Alcoholism; Notice of Meeting

    Science.gov (United States)

    2012-07-25

    ... attendance limited to space available. Individuals who plan to attend and need special assistance, such as... and the discussions could disclose confidential trade secrets or commercial property such as.... (Catalogue of Federal Domestic Assistance Program Nos. 93.273, Alcohol Research Programs; 93.701, ARRA...

  17. 78 FR 45541 - National Institute on Alcohol Abuse and Alcoholism; Notice of Meeting

    Science.gov (United States)

    2013-07-29

    ... attendance limited to space available. Individuals who plan to attend and need special assistance, such as... applications and the discussions could disclose confidential trade secrets or commercial property such as.... (Catalogue of Federal Domestic Assistance Program Nos. 93.273, Alcohol Research Programs, National Institutes...

  18. 76 FR 2129 - National Institute of Neurological Disorders And Stroke; Notice of Meeting

    Science.gov (United States)

    2011-01-12

    ... attendance limited to space available. Individuals who plan to attend and need special assistance, such as... applications and the discussions could disclose confidential trade secrets or commercial property such as... available. (Catalogue of Federal Domestic Assistance Program Nos. 93.853, Clinical Research Related to...

  19. 75 FR 20852 - National Institute on Alcohol Abuse and Alcoholism; Notice of Meeting

    Science.gov (United States)

    2010-04-21

    ... attendance limited to space available. Individuals who plan to attend and need special assistance, such as... applications and the discussions could disclose confidential trade secrets or commercial property such as... information for the meeting will be posted when available. (Catalogue of Federal Domestic Assistance Program...

  20. 75 FR 51275 - National Institute of Dental and Craniofacial Research; Notice of Meeting

    Science.gov (United States)

    2010-08-19

    ... attendance limited to space available. Individuals who plan to attend and need special assistance, such as... applications and the discussions could disclose confidential trade secrets or commercial property such as... posted when available. (Catalogue of Federal Domestic Assistance Program Nos. 93.121, Oral Diseases and...

  1. 76 FR 26308 - National Institute on Alcohol Abuse And Alcoholism; Notice of Meeting.

    Science.gov (United States)

    2011-05-06

    ... attendance limited to space available. Individuals who plan to attend and need special assistance, such as... applications and the discussions could disclose confidential trade secrets or commercial property such as... the meeting will be posted when available. (Catalogue of Federal Domestic Assistance Program Nos. 93...

  2. 78 FR 50066 - National Institute of Dental and Craniofacial Research; Notice of Meeting

    Science.gov (United States)

    2013-08-16

    ... indicated below, with attendance limited to space available. Individuals who plan to attend and need special.... The grant applications and the discussions could disclose confidential trade secrets or commercial... information for the meeting will be posted when available. (Catalogue of Federal Domestic Assistance Program...

  3. 77 FR 67438 - Defense Trade Advisory Group; Notice of Open Meeting

    Science.gov (United States)

    2012-11-09

    ... Control System (VACS-D) database. Please see the Security Records System of Records Notice (State-36) at... Security may not be able to complete the necessary processing required to attend the plenary session. A... list will be provided to Diplomatic Security. One of the following forms of valid photo identification...

  4. 76 FR 24464 - Federal Register Notice Requesting Nominations for the Subcommittee on Data Standardization Under...

    Science.gov (United States)

    2011-05-02

    ... notice. ADDRESSES: Nominations should be sent to Andrei Kirilenko, Chief Economist, Office of the Chief Economist, U.S. Commodity Futures Trading Commission, 1155 21st Street, NW., Washington, DC 20581. FOR...

  5. Odorous and non-fatal skin secretion of adult wrinkled frog (Rana rugosa is effective in avoiding predation by snakes.

    Directory of Open Access Journals (Sweden)

    Yuri Yoshimura

    Full Text Available The roles played by nonfatal secretions of adult anurans in the avoidance of predation remain unknown. The adult Wrinkled frog (Rana rugosa has warty skin with the odorous mucus secretion that is not fatal to the snake Elaphe quadrivirgata. We fed R. rugosa or Fejervarya limnocharis, which resembles R. rugosa in appearance and has mucus secretion, to snakes and compared the snakes' responses to the frogs. Compared to F. limnocharis, R. rugosa was less frequently bitten or swallowed by snakes. The snakes that bit R. rugosa spat out the frogs and showed mouth opening (gaping behavior, while the snakes that bit F. limnocharis did not show gaping behavior. We also compared the responses of the snakes to R. rugosa and F. limnocharis secretions. We coated palatable R. japonica with secretions from R. rugosa or F. limnocharis. The frogs coated by R. rugosa secretion were less frequently bitten or swallowed than those coated by F. limnocharis secretion. We concluded that compared to different frog species of similar sizes, the adult R. rugosa was less frequently preyed upon by, and that its skin secretion was effective in avoiding predation by snakes.

  6. Odorous and non-fatal skin secretion of adult wrinkled frog (Rana rugosa) is effective in avoiding predation by snakes.

    Science.gov (United States)

    Yoshimura, Yuri; Kasuya, Eiiti

    2013-01-01

    The roles played by nonfatal secretions of adult anurans in the avoidance of predation remain unknown. The adult Wrinkled frog (Rana rugosa) has warty skin with the odorous mucus secretion that is not fatal to the snake Elaphe quadrivirgata. We fed R. rugosa or Fejervarya limnocharis, which resembles R. rugosa in appearance and has mucus secretion, to snakes and compared the snakes' responses to the frogs. Compared to F. limnocharis, R. rugosa was less frequently bitten or swallowed by snakes. The snakes that bit R. rugosa spat out the frogs and showed mouth opening (gaping) behavior, while the snakes that bit F. limnocharis did not show gaping behavior. We also compared the responses of the snakes to R. rugosa and F. limnocharis secretions. We coated palatable R. japonica with secretions from R. rugosa or F. limnocharis. The frogs coated by R. rugosa secretion were less frequently bitten or swallowed than those coated by F. limnocharis secretion. We concluded that compared to different frog species of similar sizes, the adult R. rugosa was less frequently preyed upon by, and that its skin secretion was effective in avoiding predation by snakes.

  7. Modelling the introduction and spread of non-native species: international trade and climate change drive ragweed invasion.

    Science.gov (United States)

    Chapman, Daniel S; Makra, László; Albertini, Roberto; Bonini, Maira; Páldy, Anna; Rodinkova, Victoria; Šikoparija, Branko; Weryszko-Chmielewska, Elżbieta; Bullock, James M

    2016-09-01

    Biological invasions are a major driver of global change, for which models can attribute causes, assess impacts and guide management. However, invasion models typically focus on spread from known introduction points or non-native distributions and ignore the transport processes by which species arrive. Here, we developed a simulation model to understand and describe plant invasion at a continental scale, integrating repeated transport through trade pathways, unintentional release events and the population dynamics and local anthropogenic dispersal that drive subsequent spread. We used the model to simulate the invasion of Europe by common ragweed (Ambrosia artemisiifolia), a globally invasive plant that causes serious harm as an aeroallergen and crop weed. Simulations starting in 1950 accurately reproduced ragweed's current distribution, including the presence of records in climatically unsuitable areas as a result of repeated introduction. Furthermore, the model outputs were strongly correlated with spatial and temporal patterns of ragweed pollen concentrations, which are fully independent of the calibration data. The model suggests that recent trends for warmer summers and increased volumes of international trade have accelerated the ragweed invasion. For the latter, long distance dispersal because of trade within the invaded continent is highlighted as a key invasion process, in addition to import from the native range. Biosecurity simulations, whereby transport through trade pathways is halted, showed that effective control is only achieved by early action targeting all relevant pathways. We conclude that invasion models would benefit from integrating introduction processes (transport and release) with spread dynamics, to better represent propagule pressure from native sources as well as mechanisms for long-distance dispersal within invaded continents. Ultimately, such integration may facilitate better prediction of spatial and temporal variation in invasion

  8. 78 FR 17993 - Defense Trade Advisory Group; Notice of Open Meeting

    Science.gov (United States)

    2013-03-25

    ... policies, regulations, and technical issues affecting defense trade. The purpose of the meeting will be to... discussed: review of the current definitions of technical data, as well as the control language applied in... statement to the committee in writing. As seating is limited to 125 persons, those wishing to attend the...

  9. Bilateral Trade Flows and Income Distribution Similarity

    Science.gov (United States)

    2016-01-01

    Current models of bilateral trade neglect the effects of income distribution. This paper addresses the issue by accounting for non-homothetic consumer preferences and hence investigating the role of income distribution in the context of the gravity model of trade. A theoretically justified gravity model is estimated for disaggregated trade data (Dollar volume is used as dependent variable) using a sample of 104 exporters and 108 importers for 1980–2003 to achieve two main goals. We define and calculate new measures of income distribution similarity and empirically confirm that greater similarity of income distribution between countries implies more trade. Using distribution-based measures as a proxy for demand similarities in gravity models, we find consistent and robust support for the hypothesis that countries with more similar income-distributions trade more with each other. The hypothesis is also confirmed at disaggregated level for differentiated product categories. PMID:27137462

  10. A new (k,n verifiable secret image sharing scheme (VSISS

    Directory of Open Access Journals (Sweden)

    Amitava Nag

    2014-11-01

    Full Text Available In this paper, a new (k,n verifiable secret image sharing scheme (VSISS is proposed in which third order LFSR (linear-feedback shift register-based public key cryptosystem is applied for the cheating prevention and preview before decryption. In the proposed scheme the secret image is first partitioned into several non-overlapping blocks of k pixels. Every k pixel is then used to form m=⌈k/4⌉+1 pixels of one encrypted share. The original secret image can be reconstructed by gathering any k or more encrypted shared images. The experimental results show that the proposed VSISS is an efficient and safe method.

  11. How did Trade Norms Evolve in Scandinavia?

    DEFF Research Database (Denmark)

    Svendsen, Gunnar Lind Haase; Svendsen, Gert Tinggaard

    2016-01-01

    in the world today, we argue that one possible historical root of social trust may be the long-distance trade practices of the Viking age. To manage the risk of being cheated, trade between strangers in an oral world required a strong informal institution of trust-based trade norms out of necessity to deal...... with the risk of being cheated. In contrast to similar cases like the famous medieval Maghribi traders, who counted on writing (Greif, 1989), the punishment of cheaters could not be supported by written documents such as legal documents and letters, as the large majority of Vikings were non...

  12. Non-opiate [beta]-endorphin fragments and dopamine--V [gamma]-type endorphins and prolactin secretion in rats

    NARCIS (Netherlands)

    Lamberts, S.W.J.; De Quijada, M.; Ree, J.M. van; Wied, D. de

    1982-01-01

    The effects on prolactin secretion of three peptide-derivatives of β-endorphin which show neuroleptic-like activities in rats were studied. Intravenous administration of γ-endorphin (β-endorphin (βE) 1–17) enhanced plasma prolactin levels. γ-Endorphin did not affect the prolactin secretion by

  13. Characterizing copper flows in international trade of China, 1975-2015.

    Science.gov (United States)

    Zhang, Ling; Chen, Tianming; Yang, Jiameng; Cai, Zhijian; Sheng, Hu; Yuan, Zengwei; Wu, Huijun

    2017-12-01

    Since the economic reform, China has actively participated in the global market with rapid industrialization and gradually dominated the utilization and consumption of some critical materials, one of which is copper. China has reigned the global anthropogenic cycle of copper since 2004. We explore copper flows along with the international trade of China during 1975-2015, through life cycle lens, from ore to final products. Our main finding is that China has become more active in the copper-related trade, indicated by its great increase in trade volume and the number of trade partners. The physical volume of copper flows through trade increased over 119 times between 1975 and 2015, mainly because of more imported raw materials of copper and exported copper products. Generally, China is a net importer of copper, with increasing import dependence through the study period, whereas the degree of dependence slightly decreased from 2010 to 2015. The indicator of Export Support Rate took a decreasing percentage, which has fallen about 35% since 2010. It suggests China's changing position in the global resource and manufacturing market. In terms of trade price of different copper products, the price of imported copper concentrate was noticeably higher than that of exported one, revealing the poor copper resource endowment of China; while the different trend of copper semis in recent years signifies that China is in urgent need to improve its capability of producing high value-added semis. From international trade perspective, the copper resource of China presented stable supply as well as demand. The One Belt One Road strategy proposed by the state will further expand both the resource and market of copper. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. 76 FR 21384 - Office of the Director, National Institutes of Health; Notice of Meeting

    Science.gov (United States)

    2011-04-15

    .... The meeting will be open to the public as indicated below, with attendance limited to space available... confidential trade secrets or commercial property such as patentable material, and personal information..., MD 20892. Contact Person: Robin Kawazoe, Executive Secretary, Division Of Program Coordination...

  15. 77 FR 1699 - Office of the Director, National Institutes of Health; Notice of Meeting

    Science.gov (United States)

    2012-01-11

    .... The meeting will be open to the public as indicated below, with attendance limited to space available... confidential trade secrets or commercial property such as patentable material, and personal information... Program (ORIP), Division of Program Coordination, Planning, and Strategic Initiatives Update, and...

  16. 78 FR 20671 - Office of the Director, National Institutes of Health; Notice of Meeting

    Science.gov (United States)

    2013-04-05

    ... Councils. The meeting will be open to the public as indicated below, with attendance limited to space... discussions could disclose confidential trade secrets or commercial property such as patentable material, and... Epigenomics Program, Scientific Presentation, NIH Update, Concept Clearance and Discussion. Place: National...

  17. Carbon trading: Current schemes and future developments

    International Nuclear Information System (INIS)

    Perdan, Slobodan; Azapagic, Adisa

    2011-01-01

    This paper looks at the greenhouse gas (GHG) emissions trading schemes and examines the prospects of carbon trading. The first part of the paper gives an overview of several mandatory GHG trading schemes around the world. The second part focuses on the future trends in carbon trading. It argues that the emergence of new schemes, a gradual enlargement of the current ones, and willingness to link existing and planned schemes seem to point towards geographical, temporal and sectoral expansion of emissions trading. However, such expansion would need to overcome some considerable technical and non-technical obstacles. Linking of the current and emerging trading schemes requires not only considerable technical fixes and harmonisation of different trading systems, but also necessitates clear regulatory and policy signals, continuing political support and a more stable economic environment. Currently, the latter factors are missing. The global economic turmoil and its repercussions for the carbon market, a lack of the international deal on climate change defining the Post-Kyoto commitments, and unfavourable policy shifts in some countries, cast serious doubts on the expansion of emissions trading and indicate that carbon trading enters an uncertain period. - Highlights: → The paper provides an extensive overview of mandatory emissions trading schemes around the world. → Geographical, temporal and sectoral expansion of emissions trading are identified as future trends. → The expansion requires considerable technical fixes and harmonisation of different trading systems. → Clear policy signals, political support and a stable economic environment are needed for the expansion. → A lack of the post-Kyoto commitments and unfavourable policy shifts indicate an uncertain future for carbon trading.

  18. Trade and health: an agenda for action

    Science.gov (United States)

    Smith, Richard D; Lee, Kelley; Drager, Nick

    2009-01-01

    The processes of contemporary globalisation are creating ever-closer ties between individuals and populations across different countries. The health of a population, and the systems in place to deliver health care, are affected increasingly by factors beyond the population and health system. The Lancet’s Series on trade and health has provided an overview of these links between international trade, trade liberalisation, and health, and raised the key issues that face the health community. In this final paper in the Series, we call for a substantial and sustained effort by those within the health profession to engage with issues of trade, to strengthen institutional capacity in this area, and to place health higher on the agenda of trade negotiations. The rapid rise of trade agreements and treaties, as well as trade that occurs beyond these institutional boundaries, means that further action is required by a range of actors, including WHO, the World Bank, the World Trade Organization (WTO), regional agencies, foundations, national governments, civil society, non-governmental organisations, and academics. The stewardship of a domestic health system in the 21st century requires a sophisticated understanding of how trade affects, and will affect, a country’s health system and policy, to optimise opportunities to benefit health and health care while minimising the risks posed though the assertion of health goals in trade policy. To acheive this will place a premium on all those engaged in health to understand the importance of trade and to engage with their counterparts involved in trade and trade policy. We hope that this Series has prompted the reader to become involved in these efforts. PMID:19167056

  19. Trade and health: an agenda for action.

    Science.gov (United States)

    Smith, Richard D; Lee, Kelley; Drager, Nick

    2009-02-28

    The processes of contemporary globalisation are creating ever-closer ties between individuals and populations across different countries. The health of a population, and the systems in place to deliver health care, are affected increasingly by factors beyond the population and health system. The Lancet's Series on trade and health has provided an overview of these links between international trade, trade liberalisation, and health, and raised the key issues that face the health community. In this final paper in the Series, we call for a substantial and sustained effort by those within the health profession to engage with issues of trade, to strengthen institutional capacity in this area, and to place health higher on the agenda of trade negotiations. The rapid rise of trade agreements and treaties, as well as trade that occurs beyond these institutional boundaries, means that further action is required by a range of actors, including WHO, the World Bank, the World Trade Organization (WTO), regional agencies, foundations, national governments, civil society, non-governmental organisations, and academics. The stewardship of a domestic health system in the 21st century requires a sophisticated understanding of how trade affects, and will affect, a country's health system and policy, to optimise opportunities to benefit health and health care while minimising the risks posed though the assertion of health goals in trade policy. To acheive this will place a premium on all those engaged in health to understand the importance of trade and to engage with their counterparts involved in trade and trade policy. We hope that this Series has prompted the reader to become involved in these efforts.

  20. LcrG secretion is not required for blocking of Yops secretion in Yersinia pestis

    Directory of Open Access Journals (Sweden)

    Matson Jyl S

    2008-02-01

    Full Text Available Abstract Background LcrG, a negative regulator of the Yersinia type III secretion apparatus has been shown to be primarily a cytoplasmic protein, but is secreted at least in Y. pestis. LcrG secretion has not been functionally analyzed and the relevance of LcrG secretion on LcrG function is unknown. Results An LcrG-GAL4AD chimera, originally constructed for two-hybrid analyses to analyze LcrG protein interactions, appeared to be not secreted but the LcrG-GAL4AD chimera retained the ability to regulate Yops secretion. This result led to further investigation to determine the significance of LcrG secretion on LcrG function. Additional analyses including deletion and substitution mutations of amino acids 2–6 in the N-terminus of LcrG were constructed to analyze LcrG secretion and LcrG's ability to control secretion. Some changes to the N-terminus of LcrG were found to not affect LcrG's secretion or LcrG's secretion-controlling activity. However, substitution of poly-isoleucine in the N-terminus of LcrG did eliminate LcrG secretion but did not affect LcrG's secretion controlling activity. Conclusion These results indicate that secretion of LcrG, while observable and T3SS mediated, is not relevant for LcrG's ability to control secretion.

  1. External Sector Rebalancing and Endogenous Trade Imbalance Models

    Directory of Open Access Journals (Sweden)

    John Whalley

    2012-12-01

    Full Text Available I discuss the need for trade models to incorporate endogenous trade imbalances both to more adequately capture the reality of a global economy with large imbalances and pressures from the financial crisis for countries to reduce imbalances. Conventional general equilibrium trade models implicitly incorporate monetary neutrality and either have zero trade balance as a property of equilibrium, or have a fixed and exogenous trade imbalance. Models which are discussed here have a variety of forms. In one, central banks fix exchange rates and operate a non accommodative monetary policy and accumulate reserves. Changes in both trade and monetary policies change reserve accumulative and with the external sector imbalances. This is a reflection of China’s current policy regime. In another intertemporal preferences allow for simultaneous inter commodity and intertemporal trade across countries, and with changed intertemporal trade changed external sector imbalances within the period. These formulations are each applied to potential tax initiatives to aid in rebalancing.

  2. Tamper-proof secret image-sharing scheme for identifying cheated secret keys and shared images

    Science.gov (United States)

    Chen, Chien-Chang; Liu, Chong-An

    2013-01-01

    A (t,n) secret image-sharing scheme shares a secret image to n participants, and the t users recover the image. During the recovery procedure of a conventional secret image-sharing scheme, cheaters may use counterfeit secret keys or modified shared images to cheat other users' secret keys and shared images. A cheated secret key or shared image leads to an incorrect secret image. Unfortunately, the cheater cannot be identified. We present an exponent and modulus-based scheme to provide a tamper-proof secret image-sharing scheme for identifying cheaters on secret keys or shared images. The proposed scheme allows users to securely select their secret key. This assignment can be performed over networks. Modulus results of each shared image is calculated to recognize cheaters of a shared image. Experimental results indicate that the proposed scheme is excellent at identifying cheated secret keys and shared images.

  3. Correlation of secretion of retinol and protein by the lacrimal gland

    International Nuclear Information System (INIS)

    Ubels, J.L.; Rismondo, V.

    1986-01-01

    Retinol, which is present in tears, is secreted by the lacrimal gland. Retinol secretion is stimulated by cholinergic drugs and vasoactive intestinal peptide with characteristics very similar to the exocytotic secretion of protein by the lacrimal gland, suggesting that retinol and protein are secreted by similar mechanisms. The authors investigated this by cannulating the lacrimal gland ducts of rabbits and collecting lacrimal gland fluid (LGF) under conditions of maximal flow stimulated by IV injection of pilocarpine (400 μg/kg) every 20 min for 4.5 hr. Over this period LGF protein concentration decreased 36.4% from 22.8 +/- 1.94 mg/ml to 8.29 1.86 mg/ml while retinol decreased 37% from 55.1 +/- 16.2 ng/ml to 20.4 +/- 6.5 ng/ml. The retinol/protein ratio remained constant at 2.88 ng/mg. This demonstrates a strong correlation between retinol and protein secretion, suggesting that retinol may be protein bound. To investigate binding of retinol to LGF protein, LGF was incubated with 3 H-retinol. The bound and unbound retinol were separated on a Lipidex 1000 column. Retinol binding was linear over a range of 1.25-200 nM 3 H-retinol. Binding was not inhibited by PCMBS or addition of a 100-fold excess of unlabeled retinol and was not increased by prior extraction of endogenous retinol from the LGF. This indicates that the binding of retinol to LGF protein is non-specific. Retinol therefore appears to be secreted by the lacrimal gland cells in non-specific association with protein

  4. 75 FR 53319 - National Institute of Neurological Disorders and Stroke; Notice of Meetings

    Science.gov (United States)

    2010-08-31

    ... below, with attendance limited to space available. Individuals who plan to attend and need special.... The grant applications and the discussions could disclose confidential trade secrets or commercial... Development, and Special Programs Subcommittee. Date: September 22, 2010. Open: 6 p.m. to 7 p.m. Agenda: To...

  5. 78 FR 20932 - National Institute on Alcohol Abuse and Alcoholism; Notice of Meeting

    Science.gov (United States)

    2013-04-08

    ... attendance limited to space available. Individuals who plan to attend and need special assistance, such as... applications and the discussions could disclose confidential trade secrets or commercial property such as... Assistance Program Nos. 93.273, Alcohol Research Programs, National Institutes of Health, HHS) Dated: April 2...

  6. Wrapped up in Covers: Preschoolers' Secrets and Secret Hiding Places

    Science.gov (United States)

    Corson, Kimberly; Colwell, Malinda J.; Bell, Nancy J.; Trejos-Castillo, Elizabeth

    2014-01-01

    In this qualitative study, interviews about children's secret hiding places were conducted with 3-5-year-olds (n?=?17) in a university sponsored preschool programme using art narratives. Since prior studies indicate that children understand the concept of a secret as early as five and that they associate secrets with hiding places, the purpose of…

  7. 76 FR 5594 - National Institute of Environmental Health Sciences; Notice of Meeting

    Science.gov (United States)

    2011-02-01

    ... attendance limited to space available. Individuals who plan to attend and need special assistance, such as... applications and the discussions could disclose confidential trade secrets or commercial property such as...: February 16, 2011, 8:30 a.m. to 2:45 p.m. Agenda: Discussion of program policies and issues. Place: Nat...

  8. 75 FR 29774 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed...

    Science.gov (United States)

    2010-05-27

    ... could disclose confidential trade secrets or commercial property such as patentable material, and... Institute of Child Health and Human Development Initial Review Group Function, Integration, and Rehabilitation Sciences Subcommittee; Function, Integration and Rehabilitation Sciences Subcommittee. Date: June...

  9. 78 FR 50394 - Advisory Committee on Supply Chain Competitiveness: Notice of Public Meeting

    Science.gov (United States)

    2013-08-19

    ... Competitiveness: Notice of Public Meeting AGENCY: International Trade Administration, U.S. Department of Commerce... discussion for a public meeting of the Advisory Committee on Supply Chain Competitiveness (Committee). DATES... growth competitiveness, foster national economic competitiveness, and improve U.S. supply chain...

  10. Salmonella-secreted Virulence Factors

    Energy Technology Data Exchange (ETDEWEB)

    Heffron, Fred; Niemann, George; Yoon, Hyunjin; Kidwai, Afshan S.; Brown, Roslyn N.; McDermott, Jason E.; Smith, Richard D.; Adkins, Joshua N.

    2011-05-01

    In this short review we discuss secreted virulence factors of Salmonella, which directly affect Salmonella interaction with its host. Salmonella secretes protein to subvert host defenses but also, as discussed, to reduce virulence thereby permitting the bacteria to persist longer and more successfully disperse. The type III secretion system (TTSS) is the best known and well studied of the mechanisms that enable secretion from the bacterial cytoplasm to the host cell cytoplasm. Other secretion systems include outer membrane vesicles, which are present in all Gram-negative bacteria examined to date, two-partner secretion, and type VI secretion will also be addressed. Excellent reviews of Salmonella secreted effectors have focused on themes such as actin rearrangements, vesicular trafficking, ubiquitination, and the activities of the virulence factors themselves. This short review is based on S. Typhimurium infection of mice because it is a model of typhoid like disease in humans. We have organized effectors in terms of events that happen during the infection cycle and how secreted effectors may be involved.

  11. 75 FR 80511 - National Institute on Alcohol Abuse And Alcoholism; Notice of Closed Meeting

    Science.gov (United States)

    2010-12-22

    ... attendance limited to space available. Individuals who plan to attend and need special assistance, such as... applications and the discussions could disclose confidential trade secrets or commercial property such as... Domestic Assistance Program Nos.: 93.271, Alcohol Research Career Development Awards for Scientists and...

  12. 75 FR 47819 - National Institute on Alcohol Abuse and Alcoholism; Notice of Closed Meeting

    Science.gov (United States)

    2010-08-09

    ... attendance limited to space available. Individuals who plan to attend and need special assistance, such as... applications and the discussions could disclose confidential trade secrets or commercial property such as... Domestic Assistance Program Nos.: 93.271, Alcohol Research Career Development Awards for Scientists and...

  13. 78 FR 55749 - Office of the Director, National Institutes of Health; Notice of Meeting

    Science.gov (United States)

    2013-09-11

    ... Councils. The meeting will be open to the public as indicated below, with attendance limited to space... discussions could disclose confidential trade secrets or commercial property such as patentable material, and... NIH Update; Overview of Shared and High-End, Instrumentation Program; Scientific Presentation. Place...

  14. 77 FR 47858 - Office of The Director, National Institutes of Health; Notice of Meeting

    Science.gov (United States)

    2012-08-10

    .... The meeting will be open to the public as indicated below, with attendance limited to space available... disclosure of trade secrets and/or commercial or confidential financial information obtained from a person... Secretary, Division of Program Coordination, Planning, and Strategic Initiatives, Office of The Director...

  15. 78 FR 78983 - Office of the Director, National Institutes of Health; Notice of Meeting

    Science.gov (United States)

    2013-12-27

    ... Councils. The meeting will be open to the public as indicated below, with attendance limited to space... discussions could disclose confidential trade secrets or commercial property such as patentable material, and... Behavior Change Program. Update on Common Fund Planning and Management Working Group. Place: National...

  16. Trading volume and the number of trades

    OpenAIRE

    Marwan Izzeldin

    2007-01-01

    Trading volume and the number of trades are both used as proxies for market activity, with disagreement as to which is the better proxy for market activity. This paper investigates this issue using high frequency data for Cisco and Intel in 1997. A number of econometric methods are used, including GARCH augmented with lagged trading volume and number of trades, tests based on moment restrictions, regression analysis of volatility on volume and trades, normality of returns when standardized by...

  17. Regional Trade Agreement and Agricultural Trade in East African ...

    African Journals Online (AJOL)

    Intra-EAC trade is very low, that is, at 9 per cent of the total regional trade, but it is on upward trend. Agricultural trade accounts for over 40 per cent of the intra-EAC trade. This study investigated the effect of EAC regional trade agreement on the regions agricultural trade by analyzing the degree of trade creation and ...

  18. 78 FR 71628 - National Institute on Alcohol Abuse and Alcoholism; Notice of Meeting

    Science.gov (United States)

    2013-11-29

    ... attendance limited to space available. Individuals who plan to attend and need special assistance, such as... applications and the discussions could disclose confidential trade secrets or commercial property such as...' evaluation of NIAAA's Intramural Programs. Open: 2:00 p.m. to 5:00 p.m. Agenda: Presentations and other...

  19. Surfactant secretion and clearance in the newborn

    International Nuclear Information System (INIS)

    Stevens, P.A.; Wright, J.R.; Clements, J.A.

    1989-01-01

    Pregnant rabbits (30 days) were injected intravenously with [3H]choline 8 h before delivery. The fetuses were delivered, and lung lavage and lamellar body phospholipids (PL) were analyzed. Some newborns also received radioactively labeled surfactant intratracheally on delivery and were permitted to breathe. With time, intratracheal label decreased in lavage and appeared in the lamellar body fraction, and intravenous label accumulated in both pools. Using a tracer analysis for non-steady state, we calculated surfactant secretion and clearance rates for the newborn period. Before birth, both rates rose slightly from 1.8 micrograms PL.g body wt-1.h-1 at 6 h before birth to 7.3 at birth. Immediately after birth, secretion rate rose to 37.7 micrograms PL.g body wt-1.h-1. Between 1.5 and 2 h after birth it fell to a minimum of 1.8 micrograms PL.g body wt-1.h-1 and then rose slowly to 6.0 at 12 h. After birth, clearance rate increased less than secretion rate (maximum 24.7 micrograms PL.g body wt-1.h-1 shortly after birth) then followed the same pattern but did not balance secretion rate in the 1st day

  20. Trade Policy

    OpenAIRE

    Murray Gibbs

    2007-01-01

    In an otherwise insightful and thoughtful article, Sebastian Pfotenhauer (Trade Policy Is Science Policy,” Issues, Fall 2013) might better have entitled his contribution “Trade Policy Needs to Be Reconciled with Science Policy.” The North American Free Trade Agreement (NAFTA) and the agreements administered by the World Trade Organization, particularly the General Agreement on Tariffs and Trade (GATT) and the Technical Barriers to Trade (TBT), were adopted to promote international trade and i...