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Sample records for non-proliferation regime inmac

  1. Strengthening the nuclear non-proliferation regime

    International Nuclear Information System (INIS)

    Carlson, J.

    2003-01-01

    Although the nuclear non-proliferation regime has enjoyed considerable success, today the regime has never been under greater threat. Three states have challenged the objectives of the NPT, and there is a technology challenge - the spread of centrifuge enrichment technology and know-how. A major issue confronting the international community is, how to deal with a determined proliferator? Despite this gloomy scenario, however, the non-proliferation regime has considerable strengths - many of which can be developed further. The regime comprises complex interacting and mutually reinforcing elements. At its centre is the NPT - with IAEA safeguards as the Treaty's verification mechanism. Important complementary elements include: restraint in the supply and the acquisition of sensitive technologies; multilateral regimes such as the CTBT and proposed FMCT; various regional and bilateral regimes; the range of security and arms control arrangements outside the nuclear area (including other WMD regimes); and the development of proliferation-resistant technologies. Especially important are political incentives and sanctions in support of non-proliferation objectives. This paper outlines some of the key issues facing the non-proliferation regime

  2. Strengthening the non proliferation regime: French views

    International Nuclear Information System (INIS)

    Delaune, P.

    2013-01-01

    3 main issues can be identified in the French policy concerning the backing of non proliferation: 1) responding resolutely to proliferation crises, 2) reinforcing substantive efforts to prevent and impede proliferation, and 3) strengthening the non-proliferation regime. The first issue is very important because combating proliferation is vital to the security of all. Concerning the second issue, France attaches particular importance to strengthening specific measures to prevent and check proliferation. Let me mention a few proposals that we put forward: exports need to be controlled more effectively, proliferation activities have to be criminalized, or the development of proliferation-resistant technologies should be supported. Concerning the third issue it means the strengthening of the non-proliferation regime, France proposes several means: -) aiming at the universalization of the additional protocol; -) ensuring that the Agency continues to have sufficient human, financial and technical resources to fulfill its verification mission effectively; -) encouraging the IAEA to make full use of the authority available to it; -) enhancing the use of information relevant to the delivery of the IAEA mandate; and -) sharing more accurate information concerning the breaches of commitments that happen. The paper is followed by the slides of the presentation. (A.C.)

  3. Perspectives of the nuclear non-proliferation regime

    International Nuclear Information System (INIS)

    Koungou, Leon

    2004-01-01

    To join traditional methods and new approaches of 'non-proliferation'. This is a technical method and the best way to fight against 'non-proliferation' which is facing few preoccupations: knowledge's disseminations; technologies; equipments and weapons that should be stopped. As it's important to note the return of nuclear danger as the end of confrontation between west-east which should be reduce. As the adaptation of mechanisms is necessary today, as it is important to react about states' incitations to violate international engagement of non-proliferation. Areas control allows finding out change and evolution, but more insufficient. Functional difficulties show that the IAEA (International Agency of Atomic Energy) does not work good. Safeguard system does not allow to respect 'non-proliferation' engagements; for instance 'junkies states' that they cannot dissuade traditional methods. The fight of 'non-proliferation' shows new progresses with fearing methods of prevention actions and heaviest international controls of exportation. The target of this is very ambitious. This new method is self-successful because it contributes to re-enforce international security when defeating acquisition of nuclear and mass destruction weapons by non-states factors. Therefore non-proliferation regime and especially 'non-proliferation treaty' remains delicate as long as some militaries state such USA will reject their 'non-proliferation' engagement. (author) [fr

  4. The nuclear non-proliferation regime: What it is and how it has evolved

    International Nuclear Information System (INIS)

    Priest, J.

    1999-01-01

    The nuclear non-proliferation regime commonly denotes the legal norms, voluntary undertakings and policies which the international community has developed to deal with the threat of nuclear weapons proliferation. The word 'regime' suggests a legally binding order. Some components of the non-proliferation regime are indeed legally binding. Others represent essentially political rather than legal commitments. This lecture describes the various independent but mutually reinforcing components of the non-proliferation regime. It thus touches on and highlights the particular importance of political incentives - or disincentives - to the acquisition of nuclear weapons; legal undertakings in which non-proliferation commitments are anchored; verification (specifically the IAEA Safeguards System); compliance and enforcement; export controls; physical protection measures; regional nuclear non-proliferation initiatives; and measures taken to curb proliferation in general and to strive for arms control and nuclear disarmament. The purpose of the lecture is to provide an over-arching, tour d'horizon for the more specific and detailed lectures which follow. (author)

  5. INMACS: Operating experience of a mature, computer-assisted control system for nuclear material inventory and criticality safety

    International Nuclear Information System (INIS)

    Ross, A.M.

    1983-01-01

    This paper describes the operating experience of INMACS, the Integrated Nuclear Material Accounting and Control System used in the Recycle Fuel Fabrication Laboratories at Chalk River. Since commissioning was completed in 1977, INMACS has checked and recorded approximately 3000 inventory-related transactions involved in fabricating thermal-recycle fuels of (U,Pu)0 2 and (Th,Pu)0 2 . No changes have been necessary to INMACS programs that are used by laboratory staff when moving or processing nuclear material. The various utility programs have allowed efficient management and surveillance of the INMACS data base. Hardware failures and the nuisance of system unavailability at the laboratory terminals have been minimized by regular preventative maintenance. The original efforts in the design and rigorous testing of programs have helped INMACS to be accepted enthusiastically by old and new staff of the laboratories. The work required for nuclear material inventory control is done efficiently and in an atmosphere of safety

  6. New trends of activity on supporting of non-proliferation regime

    International Nuclear Information System (INIS)

    Issaeva, G.M.; Tyupkina, O.G.

    2002-01-01

    Taking into account the necessity of all possible strengthening of non-proliferation regimes Kazakhstan participates in a number of agreements and associations: Nuclear Non-proliferation Treaty, Comprehensive Test-Ban-Treaty, International Atomic Energy Agency, Nuclear Supplier Group, Missile Technology Control Regime, Conference on Disarmament, etc. The Cooperative Threat Reduction Program (CTR) greatly influenced on the development on non-proliferation regime in Kazakhstan. During initial stage of CTR activity (1993-1995) military projects prevailed. Later (1995-1997) the projects on liquidation of infrastructure for nuclear and bio- weapons were successfully realized. Last years, since 1999, the attention was shifted towards proliferation prevention of hazardous nuclear and biological materials. Recent terrorist acts and world community activity on global safety strengthening underline an urgency of quite new problems that entirely applied to Kazakhstan: monitoring of hazardous materials; enhancement of safety systems of 'risky' facilities and technologies; creation and/or upgrading of safety systems for industry infrastructure. The proposals of these new trends of non-proliferation have been developed. Development of physical protection system for oil and gas industry infrastructure of Kazakhstan based on safety concepts of nuclear facilities; Evaluation of radionuclide contamination and safety of oil and gas facilities of the Caspian region; Counteraction to nuclear materials proliferation; Cooperative approaches in preventing/reducing of illicit trafficking and use of WMD-related explosive materials. Implementation of the project would make of substantial contribution to successful solution of either regional or global safety problem

  7. Argentina’s nuclear development and the non-proliferation regime

    OpenAIRE

    Sandra Colombo; Cristian Guglielminotti; María Nevia Vera

    2017-01-01

    The development and transfer of nuclear technology have been put under strict control due to its possible military use, leading to the creation of international non-proliferation regimes. One of the latest proposals was the creation of multilateral banks of low enriched uranium (leu). The article states that, under the goal of non-proliferation, this initiative can contribute to accentuate the asymmetry in the distribution of world economic and political power, damaging the endogenous develop...

  8. Consideration on non-proliferation regime meeting in a changing world

    International Nuclear Information System (INIS)

    Kurihara, Hiroyoshi; Kikuchi, Masahiro

    1995-01-01

    This paper presents some proposals for improvement of non-proliferation regime including safeguards structures with historical changes of international regime. Current non-proliferation regime was established under the circumstances of Cold War, and it's structure and measures were influenced by the situation of these time. Although, a couple of years have passed from end of Cold War, new world order has not established yet. Therefore, it is expected that the current regime could be improved in accordance with new world order. Generally speaking, it could be welcomed that the current regime has got some successes from two points of views, namely no new nuclear weapon states have emerged and after the establishment of NPT and all nuclear weapon state is joined NPT finally. However, it is the authors' concern that some gray countries, such as India, Pakistan and Israel, have not joined the NPT yet and cases of Iraqi and DPRK have occurred. After reviewing of such new situation, some proposals will be presented in order to strengthen the nonproliferation regime to meet current world conditions

  9. IAEA Director General calls for rededication to nuclear non-proliferation regime

    International Nuclear Information System (INIS)

    2000-01-01

    Speaking at the opening session of the Review Conference of the Treaty on the Non-Proliferation of Nuclear Weapons (NPT) in New York on April 24, 2000, the Director General of the IAEA urged all nations to commit themselves unequivocally to the basic tenets of the non-proliferation regime

  10. Use of open source information and commercial satellite imagery for nuclear nonproliferation regime compliance verification by a community of academics

    Science.gov (United States)

    Solodov, Alexander

    non-nuclear weapon states (NNWS). This community analyzes all types of unclassified publicly and commercially available information to aid in detection of violations of the non-proliferation regime. INMAC shares all of this information with the IAEA and the public. Since INMAC is composed solely by members of the academic community, this organization would not demonstrate any biases in its investigations or reporting.

  11. The year 2000 examination conference of the non-proliferation treaty and the future of the nuclear non-proliferation regime

    International Nuclear Information System (INIS)

    Grand, C.

    2001-01-01

    The nuclear weapons non-proliferation treaty (NPT), signed on July 1, 1968 and enforced on March 5, 1970, has been progressively considered as the headstone of the international non-proliferation and disarmament regime. The sixth NPT examination conference took place at New York (USA) in the year 2000, 5 years after the previous conference but also after the first nuclear weapon tests of India and Pakistan. This article recalls up the main non-proliferation events that took place between the 1995 and 2000 conferences and presents the progresses and results of the New York conference. Finally, it wonders about the ambiguities in the conclusions of this last conference. (J.S.)

  12. The world's non-proliferation regime in time

    International Nuclear Information System (INIS)

    Bunn, George

    2005-01-01

    The idea for a treaty to prevent the spread of nuclear weapons to more countries was supported unanimously by the UN General Assembly in 1961. The NPT permits the P-5 to have nuclear weapons. All other NPT signatories are 'non-nuclear-weapon States' who are prohibited from acquiring nuclear weapons. To gain their signatures, the NPT promises assistance to them in the peaceful uses of nuclear energy and negotiations toward nuclear disarmament. Besides the P-5, the treaty now has 184 countries that have promised not to have nuclear weapons and that have agreed to accept inspections by the IAEA to verify that they are carrying out their promises. However, India, Pakistan, and Israel refused to join the treaty, and the Democratic People's Republic of Korea (North Korea) withdrew from it. Of these four countries, only India and Pakistan have tested nuclear weapons. Israel and North Korea are assumed to have them. The non-proliferation regime today includes much more than the NPT. The IAEA standards for inspection were the next most important element. The IAEA inspection requirements negotiated in the early 1970s were shown to be inadequate by Iraq's success in hiding its nuclear-weapon efforts before and during the Gulf War of 1991. The Additional Protocol of 1997 is slowly replacing these requirements, but, as of December 2004, was in effect in only 62 NPT member countries. The regime includes the agreements creating nuclear-weapon free zones in Africa, Latin America, Southeast Asia, the South Pacific, and Mongolia. The countries that formed these zones are also members of the NPT. The regime includes suggestions for standards and financial assistance plus requirements for physical protection of nuclear material from theft by terrorists or others. These efforts range from the Convention on Physical Protection of Nuclear Material, to the technical assistance provided by the IAEA and some countries, to the financial assistance offered by the G-8 and some other IAEA

  13. Nuclear disarmament and evolution of the nuclear non-proliferation regime

    International Nuclear Information System (INIS)

    Bragin, V.; Carlson, J.; Bardsley, J.; Hill, J.

    1999-01-01

    The 1995 NPT Review and Extension Conference reaffirmed 'the ultimate goals of the complete elimination of nuclear weapons and a treaty on general and complete disarmament under strict and effective international control' and endorsed 'universal application of safeguards once the complete elimination of nuclear weapons has been achieved'. Hence strengthening the international non-proliferation regime and incremental broadening of its coverage towards the universal application of international safeguards in all States is a high priority albeit for the medium to long term. A tentative attempt is made in this paper to anticipate how the elements of verification under the NPT, FMCT and other conventions and arrangements related to nuclear non-proliferation will evolve against the background of the disarmament process, with the goal of achieving at some future stage an ultimate convergence of verification regimes under a complete nuclear disarmament. We think, however, that most of the new initiatives in the area of disarmament/non-proliferation should be realised during the current disarmament phase. We do not wish our model to be perceived as a rigid time-bound scheme. New initiatives should be implemented in parallel and as soon as practicable. This paper reflects the personal views of the authors and should not be taken to represent Australian Government policy. (author)

  14. The year 2000 examination conference of the non-proliferation treaty and the future of the nuclear non-proliferation regime; La conference d'examen 2000 du TNP et l'avenir du regime de non-proliferation nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Grand, C. [Institut d' Etudes Politiques de Paris, 75 (France); Ecole Speciale Militaire de Saint-Cyr-Coetquidan (France)

    2001-07-01

    The nuclear weapons non-proliferation treaty (NPT), signed on July 1, 1968 and enforced on March 5, 1970, has been progressively considered as the headstone of the international non-proliferation and disarmament regime. The sixth NPT examination conference took place at New York (USA) in the year 2000, 5 years after the previous conference but also after the first nuclear weapon tests of India and Pakistan. This article recalls up the main non-proliferation events that took place between the 1995 and 2000 conferences and presents the progresses and results of the New York conference. Finally, it wonders about the ambiguities in the conclusions of this last conference. (J.S.)

  15. Argentina’s nuclear development and the non-proliferation regime

    Directory of Open Access Journals (Sweden)

    Sandra Colombo

    2017-01-01

    Full Text Available The development and transfer of nuclear technology have been put under strict control due to its possible military use, leading to the creation of international non-proliferation regimes. One of the latest proposals was the creation of multilateral banks of low enriched uranium (leu. The article states that, under the goal of non-proliferation, this initiative can contribute to accentuate the asymmetry in the distribution of world economic and political power, damaging the endogenous development of this technology in emerging countries. Against this, the article investigates the existence of margins to maneuver in the international system from the case of study of Argentina, one of the few developing countries that have managed to export nuclear technology, and has declared the development of independent nuclear activity as a State policy

  16. Handbook for nuclear non-proliferation

    International Nuclear Information System (INIS)

    Lee, Byung Wook; Oh, Keun Bae; Lee, Kwang Seok; Lee, Dong Jin; Ko, Han Seok.

    1997-05-01

    This book analyzed international non-proliferation regime preventing from spread of nuclear weapon. This book took review from the historical background of non-proliferation regime to the recent changes and status. The regime, here, is divided into multilateral and bilateral regime. First of all, this book reports four multilateral treaties concluded for non-proliferation such as NPT, NWFZ, CTBT and others. Secondly, international organization and regimes concerned with non-proliferation are analyzed with emphasis of UN, IAEA, ZC and NSG, Regional Safeguards System and international conference. Finally, this book report the current circumstances of nuclear cooperation agreement related with Korea which is an important means for bilateral regime. (author). 13 tabs., 2 figs

  17. Handbook for nuclear non-proliferation

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Byung Wook; Oh, Keun Bae; Lee, Kwang Seok; Lee, Dong Jin; Ko, Han Seok

    1997-05-01

    This book analyzed international non-proliferation regime preventing from spread of nuclear weapon. This book took review from the historical background of non-proliferation regime to the recent changes and status. The regime, here, is divided into multilateral and bilateral regime. First of all, this book reports four multilateral treaties concluded for non-proliferation such as NPT, NWFZ, CTBT and others. Secondly, international organization and regimes concerned with non-proliferation are analyzed with emphasis of UN, IAEA, ZC and NSG, Regional Safeguards System and international conference. Finally, this book report the current circumstances of nuclear cooperation agreement related with Korea which is an important means for bilateral regime. (author). 13 tabs., 2 figs.

  18. The handbook of nuclear non-proliferation

    International Nuclear Information System (INIS)

    Yang, M. H.; Lee, B. W.; Oh, K. B.; Lee, H. M.; Ko, H. S.; Ryu, J. S.; Lee, K. S.

    2003-07-01

    This report analyzed international non-proliferation regime preventing from spread of nuclear weapon. This report took review from the historical background of non-proliferation regime to the recent changes and current status. It is here divided into multilateral and bilateral regime. First of all, this report dealt four multilateral treaties concluded for international non-proliferation such as NPT, NWFZ, CTBT and others. And international organization and regimes concerned with non-proliferation are also analyzed focused on UN, IAEA, ZC and NSG, regional safeguards system and international conferences. In addition, this report reviewed the nuclear cooperation agreement related with Korea which is a important tool for bilateral regime

  19. Crisis as opportunity. Implications of the nuclear conflict with Iran for the nuclear non-proliferation regime

    International Nuclear Information System (INIS)

    Meier, Oliver

    2014-01-01

    The conflict over the Iranian nuclear programme represents the greatest challenge for international efforts to prevent nuclear proliferation. For decades Iran has been violating obligations contained in its safeguards agreement with the International Atomic Energy Agency (IAEA) in order to become nuclear weapons capable. But what impact does the conflict over Tehran's nuclear programme have on the nuclear non-proliferation regime? In three areas there is significant overlap between efforts to find a solution with Iran and broader discussions about strengthening non-proliferation norms, rules and procedures: verification of civilian nuclear programmes, limiting the ability to produce weapons-grade fissile materials, and nuclear fuel supply guarantees. The nuclear dispute with Tehran is likely to have specific effects in each of these fields on the non-proliferation regime's norms, rules and procedures. The ninth NPT review conference, which will take place from 27 April to 22 May 2015, offers an opportunity to draw lessons from the nuclear conflict and discuss ideas for further strengthening the regime. Germany is the only non-nuclear-weapon state within the E3+3 group and the strongest proponent of nuclear disarmament. As a supporter of effective multilateralism, Berlin also bears a special responsibility for ensuring that steps to strengthen nuclear verification and control efforts in the talks with Iran also reflect the non-nuclear-weapon states' interest in disarmament and transparency on the part of the nuclear-weapons states.

  20. Crisis as opportunity. Implications of the nuclear conflict with Iran for the nuclear non-proliferation regime

    Energy Technology Data Exchange (ETDEWEB)

    Meier, Oliver

    2014-11-15

    The conflict over the Iranian nuclear programme represents the greatest challenge for international efforts to prevent nuclear proliferation. For decades Iran has been violating obligations contained in its safeguards agreement with the International Atomic Energy Agency (IAEA) in order to become nuclear weapons capable. But what impact does the conflict over Tehran's nuclear programme have on the nuclear non-proliferation regime? In three areas there is significant overlap between efforts to find a solution with Iran and broader discussions about strengthening non-proliferation norms, rules and procedures: verification of civilian nuclear programmes, limiting the ability to produce weapons-grade fissile materials, and nuclear fuel supply guarantees. The nuclear dispute with Tehran is likely to have specific effects in each of these fields on the non-proliferation regime's norms, rules and procedures. The ninth NPT review conference, which will take place from 27 April to 22 May 2015, offers an opportunity to draw lessons from the nuclear conflict and discuss ideas for further strengthening the regime. Germany is the only non-nuclear-weapon state within the E3+3 group and the strongest proponent of nuclear disarmament. As a supporter of effective multilateralism, Berlin also bears a special responsibility for ensuring that steps to strengthen nuclear verification and control efforts in the talks with Iran also reflect the non-nuclear-weapon states' interest in disarmament and transparency on the part of the nuclear-weapons states.

  1. INMACS - An approach to on-line nuclear materials accounting and control in a fuel fabrication environment

    International Nuclear Information System (INIS)

    Yan, G.; L'Archeveque, J.V.R.; Paul, R.N.

    1977-08-01

    Taking advantage of modern system technologies, the concept of an Integrated Nuclear Materials Accounting and Control System (INMACS) was formulated as an alternative solution to manual inventory procedures. The selected approach offers prospects for tackling the more general fissile materials inventory problem while satisfying the immediate requirements of the Fuel Fabrication Pilot Line at CRNL. A PDP-11/40 minicomputer system was purchased, and a Data Base Management System (DBMS) was designed and implemented to provide a uniform file handling capability. The specific requirements of the Pilot Line were met by a package of application programs. About 16 man-years have been spent on the project. INMACS has been installed in the field and its usefulness as an on-line inventory system will be demonstrated in the Pilot Line. (author)

  2. Institutional effectiveness in international regimes. An analysis of the effectiveness of the nuclear non-proliferation regime coping with the political malignity in the case of Iran

    Energy Technology Data Exchange (ETDEWEB)

    Oezden, Tugba

    2015-07-01

    Among the international security regimes, the Nuclear Non-Proliferation Regime has a prominent ranking due to the destructive power of the nuclear weapons over regional and global peace and stability. The NPT Regime has come across with two major challenges in the recent decade: North Korea and Iran. Contrary to North Korea, Iran is determined to stay as a state party to the Nuclear Non-Proliferation Treaty. The Regime still did not confirm the character and extent of Iranian nuclear program. The question of this study is ''why the processes of the NPT Regime cannot specify the nature and scope of Irans nuclear program?'' The three main the processes of the regime, which are the International Atomic Energy Agency (IAEA), the UN Security Council (UNSC) and the multilateral negotiations, are examined to determine the weaknesses of the regime. This study argues that the regime is modulated to cope with operational challenges and it remains relatively incompetent when a political challenge arises.

  3. The Non-Proliferation Treaty of Nuclear Weapons (NPT) and the insertion of the Brazilian State in its regime

    International Nuclear Information System (INIS)

    Silva, Marcos Valle Machado da

    2010-01-01

    The issue of nuclear weapons continues to appear as a focal point of International Relations. The efforts and concrete actions on disarmament, non-proliferation, and nuclear arms control are still issues that generate recurring tensions between States. However, in Brazil, there is little analysis of an academic nature about these issues and, with respect to current and prospective position of the Brazilian State in the Nuclear Weapons Non- Proliferation Regime, studies and analysis are even more scarce, or incipient. The present dissertation has as its object of study to the Treaty on the Non-Proliferation of Nuclear Weapons (NPT), the Regime arisen from NPT, and the Brazilian State insertion process in this Regime. Therefore our research work is structured in three areas: the first one is about the role of nuclear weapons in States security perception, the second is about NPT and its Regime, the third runs over the insertion of the Brazilian state in this regime. So, in summary, the research performed included the reasons that make a State to develop nuclear weapons, the NPT genesis and evolution of the perception of the meaning of that Treaty by the States, and the process and the degree of insertion of Brazil in the Nuclear Weapons Non- Proliferation Regime. The inquiry sought to place this object of study in the broader debate on Foreign Relations, based on the approaches of the discipline devoted to the question of managing the security of States, id est, the two approaches that constitute the mainstream of the discipline: the perspective theoretical liberal (and neoliberal variants) and realistic thinking (and neo-realist). Thus, we have used different theoretical lenses, which we think necessary for understanding the specific parts and causal connections between these parts of a complex issue. (author)

  4. Canada's nuclear non-proliferation policy

    International Nuclear Information System (INIS)

    1982-05-01

    Canada's non-proliferation safeguards policy has two objectives: 1) to promote a more effective and comprehensive international non-proliferation regime; and 2) to ensure that Canadian nuclear exports will not be used for any nuclear explosive purpose. By emphasizing the key role of the Non-Proliferation Treaty, promoting reliance upon and improvements in the IAEA safeguards system, treating nuclear weapon and non-weapon states alike, and working for new approaches covering reprocessing, Canada promotes attainment of the first objective. The second is served through the network of bilateral nuclear agreements that Canada has put into place with its partners. The Canadian objective in post-INFCE forums is to persuade the international community to devise a more effective and comprehensive non-proliferation regime into which Canada and other suppliers may subsume their national requirements

  5. Sustaining non-proliferation in the 1980s

    International Nuclear Information System (INIS)

    Nye, J.S.

    1984-01-01

    The subject is discussed as follows: introduction; the non-proliferation regime - 1950s to 1970s (IAEA safeguards; Non-proliferation Treaty; oil crisis; proposed sale of facilities for producing weapons-usable materials; USA position); the Carter Administration approach; INFCE (International Nuclear Fuel Cycle Evaluation); incentives (USA); export legislation (USA); domestic breeder policy (USA); maintaining the regime in the 1980s (safeguards; Pu and highly enriched uranium management; international spent fuel storage; fuel assurances); the problem of priority; rate vs. degree of proliferation; relations among regimes (international regimes); conclusion. (U.K.)

  6. Nuclear non-proliferation

    International Nuclear Information System (INIS)

    Anon.

    1990-01-01

    This patent describes the treaty on the non-proliferation of nuclear weapons which is the corner-stone of an international non-proliferation regime which has grown to embrace the overwhelming majority of countries in the world in the period since the Treaty. The other elements of the regime include, first of all, the safeguards system of IAEA-which operates to prevent the diversion of nuclear materials to military or other prohibited activities and must be accepted by all non-nuclear-weapon parties to the Treaty and, secondly, the Antarctic Treaty, the Treaty for the Prohibition of Nuclear Weapons in Latin America (Treaty of Tlatelolco) and the south Pacific Nuclear Free zone Treaty (Treaty of Rarotonga)-which serve to extend the regime geographically. The last two Treaties require safeguards agreements with IAEA. In addition, the Treaty of Tlatelolco contains provisions establishing the agency for the Prohibition of Nuclear Weapons in Latin America and the Caribbean to ensure compliance

  7. Accountability and non-proliferation nuclear regime: a review of the mutual surveillance Brazilian-Argentine model for nuclear safeguards

    International Nuclear Information System (INIS)

    Xavier, Roberto Salles

    2014-01-01

    The regimes of accountability, the organizations of global governance and institutional arrangements of global governance of nuclear non-proliferation and of Mutual Vigilance Brazilian-Argentine of Nuclear Safeguards are the subject of research. The starting point is the importance of the institutional model of global governance for the effective control of non-proliferation of nuclear weapons. In this context, the research investigates how to structure the current arrangements of the international nuclear non-proliferation and what is the performance of model Mutual Vigilance Brazilian-Argentine of Nuclear Safeguards in relation to accountability regimes of global governance. For that, was searched the current literature of three theoretical dimensions: accountability, global governance and global governance organizations. In relation to the research method was used the case study and the treatment technique of data the analysis of content. The results allowed: to establish an evaluation model based on accountability mechanisms; to assess how behaves the model Mutual Vigilance Brazilian-Argentine Nuclear Safeguards front of the proposed accountability regime; and to measure the degree to which regional arrangements that work with systems of global governance can strengthen these international systems. (author)

  8. Safeguards and non-proliferation: current challenges and the implications for Australia

    International Nuclear Information System (INIS)

    Leask, A.; Carlson, J.

    2006-01-01

    Full text: The expansion of nuclear programs raises the issue of how to ensure this does not increase the risk of nuclear weapons proliferation. The non-proliferation regime - based on the NPT and its verification mechanism, the IAEA safeguards system - has been developed to provide assurance that nuclear programs are exclusively peaceful. Although to date the non-proliferation regime has been remarkably successful, in recent years it has come under serious challenge. Nuclear proliferation is emerging as one of the major issues facing the international community. Addressing technical and institutional aspects of the non-proliferation regime - especially safeguards, but also complementary measures such as export controls, proliferation-resistant technology, and an international framework on sensitive technology - is important. But proliferation is a political problem, and ultimately the success of the non-proliferation regime depends on political resolve to uphold compliance, using incentives and if necessary sanctions. These issues are vitally important to Australia's future. Being a major uranium supplier has strengthened Australia's influence in non-proliferation and safeguards developments

  9. Future non-proliferation challenges

    International Nuclear Information System (INIS)

    Yelchenko, Volodymyr

    2008-01-01

    Having chaired the Second Session of the Preparatory Committee Mr. Volodymyr Yelchenko noted that the NPT States parties reaffirmed the important role of the Treaty as the cornerstone of the global non-proliferation regime. They stressed that non-compliance with the Treaty provisions by States parties undermined non-proliferation and placed emphasis on the mutually reinforcing nature of disarmament and non-proliferation, and due respect for the right of States parties to the peaceful use of nuclear energy in conformity with the treaty. They reaffirmed the importance of promoting the peaceful uses of nuclear energy and international nuclear cooperation for peaceful purposes in ways consistent with the non-proliferation goal of the Treaty. The universality aspect was brought to the front with the lack of progress in this area. States parties called upon India, Israel and Pakistan to accede to the Treaty as non-nuclear-weapons states, promptly and without conditions and to bring into force comprehensive safeguards agreements, together with Additional Protocols, for ensuring non-proliferation. There is concern that non-States actors could gain access to weapons of mass destruction. One of the underlying themes at the Second Prepcom was the total elimination of nuclear weapons as the only absolute guarantee against their proliferation. Negative consequences to nuclear non-proliferation were also mentioned in the context of the abrogation of the Anti-Ballistic Missile Treaty and the development of missile defense systems, with the risk of a new arms race on Earth and in outer space. The importance of the immediate commencement of negotiations in the Conference of Disarmament on a treaty concerning fissile material for nuclear weapons or other nuclear explosive devices and the urgent conclusion of such a treaty as a beneficial step towards non-proliferation was stressed. The NPT states parties reaffirmed the role of the IAEA as the sole competent authority responsible for

  10. Strengthening the nuclear non-proliferation regime: An international priority. Tokyo, 10 December 2002

    International Nuclear Information System (INIS)

    ElBaradei, M.

    2002-01-01

    The efforts to curb the spread of nuclear weapons has witnessed steady progress and a number of important milestones. Progress, however, is still required on this and many other fronts, including: the need to work energetically to ensure the universal adherence to safeguards agreements and additional protocols by all the non-nuclear-weapon States party to the NPT and other non-proliferation agreements; the need for reducing existing nuclear weapon arsenals and adopting concrete steps that move us further towards nuclear disarmament; the need to draw in those States that remain outside the NPT regime; and the need to develop alternative approaches to regional and international security that are functional and inclusive, and that do not incorporate nuclear deterrence as a feature

  11. The Nuclear Non-Proliferation Policy of the Obama Administration

    International Nuclear Information System (INIS)

    Baek, Jin Hyun; Hwang, Ji Hwan

    2009-12-01

    The objective of this study is to analyze and foresee trends of international nuclear non-proliferation regimes focused on the nuclear non-proliferation policy of the Obama administration, and suggest national policy directions which promote utilization and development of nuclear energy in Korea. For the effective and efficient implementation of the national nuclear use and development program in current international nuclear environment, many efforts should be made: to actively and positively participate in the international nuclear non-proliferation regime; to strengthen nuclear diplomacy in a more systematic manner; and to strengthen the international nuclear cooperation

  12. Twenty years of the Non-proliferation Treaty

    International Nuclear Information System (INIS)

    Goldblat, Jozef.

    1990-01-01

    The report assesses the achievements of the Non-proliferation Treaty (NPT) and discusses ways in which the non-proliferation regime could be strenghtened. It recommends a series of measures to be taken by the parties of the Treaty, both nuclear and non-nuclear weapons states, with a view to reinforcing the Treaty and achieving its universality. 198 refs

  13. Canada's nuclear non-proliferation policy

    International Nuclear Information System (INIS)

    1985-01-01

    Canada's non-proliferation and safeguards policy has two objectives: 1) to promote the emergence of a more effective and comprehensive international non-proliferation regime; and 2) to assure the Canadian people and the international community that Canadian nuclear exports will not be used for any nuclear explosive purpose. By emphasizing the key role of the NPT, by promoting reliance upon and improvements in the IAEA safeguards system, by treating nuclear weapon and non-nuclear weapon states alike regarding Canadian nuclear exports, by working for new approaches covering the sensitive phases (e.g. reprocessing) of the nuclear fuel cycle, Canada's policy promotes attainment of the first objective. The latter objective is served through the network of bilateral nuclear agreements that Canada has put into place with its nuclear partners. Those agreements provide assurance that Canada's nuclear exports are used solely for legitimate, peaceful, nuclear energy production purposes. At the same time, Canada, having formulated its non-proliferation and safeguards policy during the period 1945 to 1980, has recognized that it has gone as far as it can on its own in this field and that from this point on any further changes should be made on the basis of international agreement. The Canadian objective in post-INFCE forums such as the Committee on Assurances of Supply is to exert Canada's best efforts to persuade the international community to devise a more effective and comprehensive international non-proliferation regime into which Canada and other suppliers might subsume their national requirements

  14. The crisis bears the chance. The nuclear conflict with Iran and the impact on the nuclear non-proliferation regime; In der Krise liegt die Chance. Der Atomkonflikt mit Iran und seine Auswirkungen auf das nukleare Nichtverbreitungsregime

    Energy Technology Data Exchange (ETDEWEB)

    Meier, Oliver

    2014-10-15

    The contribution on the nuclear conflict with Iran and the impact on the nuclear non-proliferation regime covers the following topics: Iran and the verification of non-nuclear -weapon states, the system of nuclear safeguards, the application of new verification instruments, verification of possible military research and development activities, the limitation of proliferation relevant activities, delivery guarantees as mean for non-proliferation, Iran and the handling of contract violations, graded reactions, political issues, problems of harmonization, capacity and process deficiencies, before the ninth non-proliferation verification conference, approaches for strengthening the non-proliferation regime, recommendation to the German politics.

  15. From nuclear non-proliferation to nuclear disarmament: a need to refocus NPT priorities

    International Nuclear Information System (INIS)

    Sethi, Manpreet

    1998-01-01

    This paper seeks to suggest that attempts at general and complete nuclear disarmament have largely failed because of an over emphasis on nuclear non-proliferation, particularly horizontal, while disarmament has attracted only lip service from the perpetrators of nuclear weapons. In this regard, the treaty of the Non-Proliferation of Nuclear Weapons (NPT) that is deemed to be the core of the global non-proliferation regime is no less to blame for having indulged in a skewed pursuit of its twin objectives - nuclear non-proliferation and nuclear disarmament. The paper argues that nuclear non-proliferation can be sustainable only if complemented by nuclear disarmament. In the absence of the latter, proliferation of nuclear weapons, irrespective of the NPT and its safeguards regime, would always pose a potential risk

  16. The non-proliferation regime, vertical proliferation and the interests of the Federal Republic of Germany

    International Nuclear Information System (INIS)

    Fischer, W.

    1988-12-01

    The disarmament orientation of the NPT, which stands beside the central aim of avoiding horizontal proliferation, raises a question: Does a compatibility exist between the non-proliferation policy of the Federal Republic and its security policy, which has its basic pillar in the nuclear deterrence strategy? Critics of this deterrence policy therefore, hinting to the disarmament determination of the NPT, demand that the Federal Republic should exercise its influence for the conclusion of a 'Comprehensive Test Ban Treaty' (CTBT), the establishment of a 'Nuclear-Weapons-Free-Zones' (NWFZ) in Europe, a 'No First Use'-Treaty (NFU) and finally the abolishment of all atomic weapons ('Zero Solution'). According to them such disarmament 'remedies' can reestablish or assure the waning or damaged international consensus for horizontal non-proliferation. This is a contribution for the establishment of a stable world order and will smooth the way for a prolongation of the NPT in the year 1995. An analysis of the history and the structure of interests shows that the policy of the Federal Republic of Germany is deeply rooted in the NPT and that a prolongation of the treaty and its own membership is a substantial object of the foreign and security policy. Consequently the Federal Republic has to face the demands for an intensification of 'anti-nuclear measures' and has to examine their acceptability and their usefulness with respect to non-proliferation. The structure of the problem encloses the following aspects: The security conception of the Federal Republic with its military-strategic essence; the provisions in article VI NPT for negotiations with the object of a world free of atomic weapons; the derived disarmament 'remedies' for strengthening the consensus for horizontal non-proliferation and, finally, the real interface between horizontal and vertical proliferation. (orig./DG) [de

  17. Non-proliferation through effective international control. Report of working group I

    International Nuclear Information System (INIS)

    Miller, S.E.

    1993-01-01

    Working Group I focused on two issues: the nuclear non-proliferation regime and the Missile Technology Regime (MTCR). There was wide agreement within the Group on a number of factors that will strongly influence the prospects for the Non-proliferation Treaty (NPT) extension Conference. Two points stood out as particularly important: first, emphasis on the obligations for nuclear Powers to move in good faith in direction of nuclear disarmament; and second, inadequacy of security guarantees to non-nuclear States associated with the NPT

  18. Nuclear arbitration: Interpreting non-proliferation agreements

    International Nuclear Information System (INIS)

    Tzeng, Peter

    2015-01-01

    At the core of the nuclear non-proliferation regime lie international agreements. These agreements include, inter alia, the Nuclear Non-proliferation Treaty, nuclear co-operation agreements and nuclear export control agreements.1 States, however, do not always comply with their obligations under these agreements. In response, commentators have proposed various enforcement mechanisms to promote compliance. The inconvenient truth, however, is that states are generally unwilling to consent to enforcement mechanisms concerning issues as critical to national security as nuclear non-proliferation.3 This article suggests an alternative solution to the non-compliance problem: interpretation mechanisms. Although an interpretation mechanism does not have the teeth of an enforcement mechanism, it can induce compliance by providing an authoritative interpretation of a legal obligation. Interpretation mechanisms would help solve the non-compliance problem because, as this article shows, in many cases of alleged non-compliance with a non-proliferation agreement, the fundamental problem has been the lack of an authoritative interpretation of the agreement, not the lack of an enforcement mechanism. Specifically, this article proposes arbitration as the proper interpretation mechanism for non-proliferation agreements. It advocates the establishment of a 'Nuclear Arbitration Centre' as an independent branch of the International Atomic Energy Agency (IAEA), and recommends the gradual introduction of arbitration clauses into the texts of non-proliferation agreements. Section I begins with a discussion of international agreements in general and the importance of interpretation and enforcement mechanisms. Section II then discusses nuclear non-proliferation agreements and their lack of interpretation and enforcement mechanisms. Section III examines seven case studies of alleged non-compliance with non-proliferation agreements in order to show that the main problem in many cases

  19. British nuclear non-proliferation policy and the trident purchase

    International Nuclear Information System (INIS)

    Keohane, D.

    1984-01-01

    Since the mid-1950s, the UK has had a policy of making significant and sustained efforts to minimise the spread of nuclear arms. Unlike the global focus of its non-proliferation policy, the decision on Trident in centred upon national and perhaps regional requirements. At a time when non-nuclear countries are charging nuclear-weapon states with a grave failure to meet their obligations under Article VI of the NPT, Britain is making plans that would further increase the gap between the nuclear 'haves' and have-nots' and that indicate it expects to require nuclear arms in the next century. It would of course be unrealistic to expect a government to fully harmonise its manifold policies and unreasonable to suggest it should give absolute priority to one of its policy concerns, such as non-proliferation. But Britain is emphasising the high value it places upon the independent possession of strategic nuclear arms through its decision to purchase Trident, thus implicitly contradicting the logic underlying its non-proliferation policy. Compared to other factors, the influence of the Trident decision upon the non-proliferation regime appears very marginal, yet it is unlikely to strengthen that regime

  20. Accountability and non-proliferation nuclear regime: a review of the mutual surveillance Brazilian-Argentine model for nuclear safeguards; Accountability e regime de nao proliferacao nuclear: uma avaliacao do modelo de vigilancia mutua brasileiro-argentina de salvaguardas nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Xavier, Roberto Salles

    2014-08-01

    The regimes of accountability, the organizations of global governance and institutional arrangements of global governance of nuclear non-proliferation and of Mutual Vigilance Brazilian-Argentine of Nuclear Safeguards are the subject of research. The starting point is the importance of the institutional model of global governance for the effective control of non-proliferation of nuclear weapons. In this context, the research investigates how to structure the current arrangements of the international nuclear non-proliferation and what is the performance of model Mutual Vigilance Brazilian-Argentine of Nuclear Safeguards in relation to accountability regimes of global governance. For that, was searched the current literature of three theoretical dimensions: accountability, global governance and global governance organizations. In relation to the research method was used the case study and the treatment technique of data the analysis of content. The results allowed: to establish an evaluation model based on accountability mechanisms; to assess how behaves the model Mutual Vigilance Brazilian-Argentine Nuclear Safeguards front of the proposed accountability regime; and to measure the degree to which regional arrangements that work with systems of global governance can strengthen these international systems. (author)

  1. Sovereignty and non-proliferation policy

    International Nuclear Information System (INIS)

    Kimminich, O.

    1990-01-01

    The Non-Proliferation Treaty seems to violate the fundamental principle of the quality of the states. However, if interpreted in the light of the latest developments of the international law, it is possible to justify the discriminations which it imposes on the non-nuclear states. A crucial point is the implementation of article VI by the nuclear states. If the latter procrastinate in nuclear disarmament the whole NPT-regime will collapse. (orig.) [de

  2. Missile non-proliferation: an alternative approach

    International Nuclear Information System (INIS)

    Delory, Stephane

    2011-01-01

    In this report, the author first proposes an overview of the notion of missile prohibition. He notices that the association between weapons of mass destruction and missiles is a prelude to the legitimacy of missile control, notably within the framework of the Missile Technology Control Regime or MTCR. He also comments the notion of total ban. In a second part, the author analyses and discusses the limitations of the control of technology diffusion. He discusses the role of the MTCR, comments the evolution of this regime with the taking of China and Russia into consideration, the impacts of national implementations of export regimes on the MTCR, and economic aspects of control implementation. In the next part, the author addresses other kinds of limitations, i.e. those related with capacity evolutions of proliferating States. The last part addresses the evolution towards a new definition of approach to missile non-proliferation, notably in terms of perception of missile roles and of technology transfer controls

  3. The Iranian Atomic program - Energy- versus Safety policy? On the problem of international non-proliferation regime

    International Nuclear Information System (INIS)

    Klimas, Mirko

    2007-01-01

    The Iranian atomic program: An important part of national energy policy or military way out of the international safety dilemma? In detail the author investigates - against background of Neorealism Theory - the coherences between international non-proliferation regimes - from Atoms for Peace program of the 1950 years up to actual measures of the IAEA - and the development of the Iranian atomic program. Off from superficial discussions on intentions of the Iranian government the book lightens the background of an international policy, which not only favours Iran during production of nuclear weapons as also invites the country to a military utilization of its atomic program. (orig./GL)

  4. The role of strategic missile defence in the global architecture de ballistic non proliferation

    International Nuclear Information System (INIS)

    Hautecouverture, Benjamin

    2007-01-01

    Whereas some think that missile defence is a proliferation agent by nature and therefore undermines the already fragile regime of ballistic non proliferation, some others think that missile defence could underpin the non proliferation regime. The author thus discusses these issues and both points of view by commenting the ambiguous discursive relationships between missile defence and arms control, and by highlighting the various roles and missions given to missile defence, notably in treaties (like the ABM treaty) and postures adopted by concerned countries

  5. 2. International conference on non-proliferation problems. Abstracts of reports

    Energy Technology Data Exchange (ETDEWEB)

    Koltysheva, G I; Perepelkin, I G [eds.

    1999-12-31

    On 14-17 September 1998, in Kurchatov (Kazakstan), II. International Conference on Non-proliferation Problems was held. Representatives from different international organizations (IAEA, UNO, CTBT Organization Preparatory Committee, Austria), from organizations of Kazakstan, Russia, USA, Japan took part in the Conference. At the conference there were 220 participants. Different issues relating to non-proliferation were discussed at the conference sections. The Conference included Plenary Session `History and Current State of Non-proliferation Problem` and three sections: (1) Practical measures to support non-proliferation regime and Control for Nuclear Tests`; (2) Problems on Eliminating Nuclear tests Consequences and Conversion of Nuclear and Industrial Complex`; (3) Medical and ecological problems of Nuclear Tests Consequences`

  6. 2. International conference on non-proliferation problems. Abstracts of reports

    International Nuclear Information System (INIS)

    Koltysheva, G.I.; Perepelkin, I.G.

    1998-01-01

    On 14-17 September 1998, in Kurchatov (Kazakstan), II. International Conference on Non-proliferation Problems was held. Representatives from different international organizations (IAEA, UNO, CTBT Organization Preparatory Committee, Austria), from organizations of Kazakstan, Russia, USA, Japan took part in the Conference. At the conference there were 220 participants. Different issues relating to non-proliferation were discussed at the conference sections. The Conference included Plenary Session 'History and Current State of Non-proliferation Problem' and three sections: 1) Practical measures to support non-proliferation regime and Control for Nuclear Tests'; 2) Problems on Eliminating Nuclear tests Consequences and Conversion of Nuclear and Industrial Complex'; 3) Medical and ecological problems of Nuclear Tests Consequences'

  7. A Study on Introduction of Nuclear Power Plants in India and the Nuclear Non- Proliferation Conditions

    International Nuclear Information System (INIS)

    Yang, Seung Hyo; Lim, Dong Hyuk

    2011-01-01

    Nuclear Suppliers Group (NSG) which was formed to build nuclear export control has been accepting the nuclear cooperation for the member nation of the international nuclear non-proliferation regime. Korea exported nuclear power plants to United Arab Emirates in 2009 and research and training reactor to Jordan in 2010 based on the forcible non-proliferation regime as a member nation of NSG, so it is strengthening its position in the atomic energy industry. In addition, Korea concluded an agreement with India which is planning the construction of 25.based or more nuclear power plants for the next 20 years in last July, 25, so it will enter the atomic energy market in India. But India has been accepted the exceptionally civilian nuclear cooperation as a de facto Nuclear Weapon State (NWS) and non-member state of NPT, so concerns about nuclear proliferation has been raised. This study aims to introduce the allowance of exceptions background in India, to analyze its effect on the non-proliferation regime and to find nuclear non-proliferation conditions

  8. Non proliferation regimes undertakings: Benefits and limits of synergies in verification technologies and procedures

    International Nuclear Information System (INIS)

    Richard, M.

    2001-01-01

    Full text: Thirty years ago the NPT was entering into force. Therewith, when a State became party to the NPT, it had, in accordance with article III.1 of the Treaty, an undertaking to conclude a Comprehensive Safeguards agreement with the IAEA and accept safeguards verification on source or special fissionable material in all peaceful nuclear activities within its territories in order to verify that such material is not diverted. This multilateral instrument was the foundation stone of the non-proliferation regime and marked the actual birth of internationally accepted measures to verily compliance with politically stringent agreements. Since that time several important multilateral or bilateral instruments on non-proliferation and disarmament have been negotiated and adopted to curb the development and the acquisition of Weapons of Mass Destruction (WMD) most of them since the middle of the eighties and the collapse of the Soviet Union. Amongst the multilateral instruments are the Convention on the Prohibition of Bacteriological Weapon and Toxin Weapons (1972), the Convention on the Prohibition of Chemical Weapons (1993), the Comprehensive Test Ban Treaty (1996), the Strengthening of the IAEA Safeguards and the Additional Protocol (1997), with some still in negotiation like the Protocol of the Convention on the Prohibition of Bacteriological and Toxin Weapons, and some on which negotiation is still a wish like the Fissile Material Cut-off Treaty. Bilateral disarmament agreements between the United States of America and the Russian Federation such as the INF Treaty, START I and II, the agreements on the elimination of excess defence nuclear material as well as the Trilateral Initiative with the IAEA pave the way to nuclear disarmament with the reduction of both the number of nuclear weapons arsenal and the fissile material inventories. The politically stringent undertakings of States that have become parties to those agreements would not be possible without the

  9. Australian Safeguards and Non-Proliferation Office, Annual Report 2001-2002

    International Nuclear Information System (INIS)

    2002-01-01

    During the year Australian Safeguards and Non-Proliferation Office (ASNO) continued our substantial contribution to the development and strengthening of international verification regimes concerned with weapons of mass destruction (WMD). Domestically, ASNO conducted, or contributed to, review of WMD- related legislation and administration, amending permits to enhance security arrangements, and beginning development of supporting legislative changes. Another major area of work is the replacement research reactor project, where ASNO has been closely involved through safeguards and security aspects. This year has been dominated by the terrorist attacks of 11 September 2001 on the United States, and ongoing consequences. These events, and the concern that terrorists would use WMD if they were able to acquire them, have served to emphasise the importance of effective counter-proliferation and counter-terrorism measures to complement the non-proliferation regimes. They have also focused attention on the need to deal with non- compliance with WMD treaty commitments. The key achivements reported for the year under review include: 1. All treaty and statutory requirements met in respect of: nuclear material and nuclear items in Australia, Australian uranium exports (Australian Obligated Nuclear Material), chemicals covered by the CWC (Chemical Weapons Convention) and establishment of CTBT(Comprehensive Nuclear-Test-Ban Treaty) monitoring stations; 2. Effective contribution to strengthening non-proliferation verification regimes and counter terrorism initiatives: ongoing support for IAEA safeguards development, regional outreach on IAEA safeguards, CWC implementation and encouraging CTBT ratification, ANSTO security upgraded; security plan approved for construction of replacement research reactor, review, with other responsible authorities, of security of CWC related chemicals, and radiation sources

  10. A study on strengthening measures of non-proliferation regime through the export control system of sensitive materials, equipment and technology related to nuclear activities

    International Nuclear Information System (INIS)

    Kikuchi, Masahiro; Kurosawa, Mitsuru; Komizo, Yasuyoshi

    2004-01-01

    The strengthened safeguards caused from safeguards experiences to Iraq and DPRK leads to the expansion of the IAEA's activities for verification of all nuclear activities as well as verification of nuclear material in the States. The purpose of the activities, of course, includes detection of undeclared exports and imports of specified equipment and non-nuclear material. The Additional Protocol to the agreements between States and the IAEA for the application of safeguards requires to the States to declare the exports and imports information regarding specified equipment and non-nuclear material corresponding to the export control list that is established by the nuclear suppliers group. The Additional Protocol also insists the IAEA's right to access to the location identified by the State to resolve a question related to the declarations. Recently, the IAEA detected the black market group of the sensitive materials, equipment and technologies relevant to the nuclear proliferation through the safeguards activities to Iran and Libya. International community stated deeply concerns to the indecent facts. This paper would discuss and propose the supplemental strengthening measures of non-proliferation regime by effective combination of the safeguards activities under additional protocol and the export control regime. (author)

  11. Activities of the study group of peaceful uses of nuclear energy and non-proliferation policy. FY Heisei 11

    International Nuclear Information System (INIS)

    Kurosawa, Mitsuru; Oi, Noboru

    2000-01-01

    The Study Group on the Peaceful Uses of Nuclear Energy and Non-Proliferation Policy (Chairman: Prof. Kurosawa) was established in FY1999 with the funding from the Science and Technology Agency. The aim of the Study Group is to clearly understand nuclear proliferation issues and to lead international opinion. Nuclear non-proliferation is a matter of rather scanty interest compared to nuclear safety while both of them are important in promoting peaceful uses of nuclear energy in Japan. In FY2000, the Study Group held International Symposium 'Peaceful Uses of Nuclear Energy and Non-Proliferation: A Challenge of 21st Century' and in conjunction with this Symposium, dispatched 'The Statement on the Peaceful Uses of Nuclear Energy and Non-Proliferation, Action Plan towards 21st Century'. The Statement consists of five propositions: 1) Strengthening the global nuclear non-proliferation regime and making it universally applicable, 2) Negative legacy of cold war: rapid solution of problems, 3) Civil (non-military) plutonium, 4) Development of technology to strengthen the nuclear non-proliferation regime internationally, and 5) Strengthening Japanese initiative on nuclear non-proliferation policy. In this report, these activities will be explained in detail. (author)

  12. Non-proliferation and safeguards aspects. Key issue paper no. 5

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-06-01

    This paper examines the current nuclear non-proliferation regime (Section 2) and the issues most likely to arise as the civil nuclear fuel cycle develops over the next 50 years (Section 3). Section 4 deals with fuel cycles and nuclear material inventories. 14 refs.

  13. Nuclear fuel cycle industry. A responsible approach supporting non proliferation efforts in global perspective

    International Nuclear Information System (INIS)

    Jorant, Caroline

    2005-01-01

    This paper presents the reasons why and the manner in which nuclear industry is a stakeholder in non proliferation efforts. It then presents some recent proposals on multinational approaches to the fuel cycle industry and offers some comments and an industry view on these issues. A parallel is established with fundamental concepts in the field of radiation protection. Our industry, involved in 'nuclear technology development' (activities) qualified of 'sensitive' from a non proliferation standpoint, has major interests at stake in the evolution of the international non proliferation regime and is genuinely committed to the spreading of a non proliferation culture. The international community and in particular the nuclear community have been recently reflecting on ways to strengthen the non-proliferation regime in reaction to new threats or the perception thereof. Multilateral approaches regarding the nuclear fuel cycle are being discussed or proposed in this regard. Our approach as an industrial may be illustrated using the three basic principles developed in the field of radiation protection, namely limitation, justification and optimization. a) an overall limitation of sensitive facilities worldwide may be judicious, b) however no prohibition should be imposed if justified needs can be demonstrated on objective criteria, c) optimized used for existing facilities should be promoted through strengthened guarantees of supply where it may be necessary. (author)

  14. Positive steps toward non-proliferation

    Energy Technology Data Exchange (ETDEWEB)

    Greenhalgh, G.

    1979-08-30

    Russel W. Fox and Mason Willrich in their paper, International Custody of Plutonium Stocks: A First Step Toward an International Regime for Sensitive Nuclear Energy Activities, advocate placing excess plutonium in an international custodial facility; critical criteria governing releases are outlined so that, on one hand the owners can have high confidence that their plutonium will be returned promptly, under appropriate circumstances, and on the other hand, all the other participating and concerned countries can have confidence in the assurance that plutonium will be released only for immediate use in a defined and approved civil purpose. The Stockholm International Peace Research Institute in the 1978 issue of its Year Book, recognizes a move towards a more positive approach to the problem of nuclear proliferation. It is noted that the non-proliferation strategies of the main supply countries have largely concentrated on a two-pronged approach of technology denials with tightening of safeguards. But already, enrichment, reprocessing, and breeder reactor programs extend far beyond the five nuclear weapon states. History testifies to the limitations of a policy of technical denials. SIPRI recognizes that another way to dissuade non-nuclear weapon states from creating their own enrichment or reprocessing plants would be to establish an open market for these services, a market characterized by diversity and competition. So far, there has been no case where a country has developed nuclear explosives by diverting material from a civil power station. Development of nuclear weapons by various countries is briefly noted and areas where strengthening of the Non-Proliferation Treaty is needed are noted. (MCW)

  15. Non-proliferation and safeguards in South Africa

    International Nuclear Information System (INIS)

    Broodryk, Alta

    2001-01-01

    South Africa occupies a unique position in the history of the Non-Proliferation Treaty in being the only country with a nuclear weapons capability that was voluntary terminated before acceding to the Treaty. The first nuclear device built was completed in December 1982, five more devices followed at an orderly pace of less than one per year and on 26 February 1990 cabinet officially implemented the termination of its nuclear deterrent capability. The events that flowed from the termination was that South Africa: Acceded to the Non-Proliferation Treaty (10 July 1991); Signed Comprehensive Safeguards Agreement, INFCIRC/394, (16 September 1991); Submitted its initial inventory of nuclear material (30 September 1991); and Received first verification team from the Agency (November 1991). South Africa, being dedicated to the prevention of the proliferation of Nuclear Weapons became a party to various non-proliferation treaties, regimes and groups. The National Non- Proliferation Policy, as published in a Cabinet memorandum, also clearly states this commitment. To comply with the requirements of the Treaty and Agreement the following two acts were published: The Nuclear Energy Act; The Non-Proliferation of Weapons of Mass Destruction Act. The Minister of Minerals and Energy is the State Authority for the implementation of the Safeguards Agreement in South Africa, however, the Minister delegated this Authority to NECSA's Safeguards Division. To implement the requirements of the various acts, control regimes and treaties a State System for Accounting and Control of Nuclear Material, based on the ISO 9001:2000 standard, was designed. This standard focuses on customer satisfaction, continuous improvement, the demonstration of commitment and the prevention of non-conformity. To comply with the requirements of the standard the following procedures were established and maintained: A Quality Manual; Customer focus; Control of documents; Control of quality records; Internal Audits

  16. Nuclear non proliferation and disarmament; Non-proliferation nucleaire et desarmement

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    In the framework of the publication of a document on the ''weapons mastership, disarmament and non proliferation: the french action'', by the ministry of Foreign Affairs and the ministry of Defense, the French Documentation organization presents a whole document. This document describes and details the following topics: the conference on the treaty of non proliferation of nuclear weapons, the France, Usa and Non Governmental Organizations position, the threats of the proliferation, the french actions towards the disarmament, the disarmament in the world, a chronology and some bibliographic resources. (A.L.B.)

  17. Nuclear non-proliferation and disarmament: A long-term perspective

    International Nuclear Information System (INIS)

    Haeckel, E.

    1990-01-01

    International nuclear policy has been determined for a long time by the exigencies of the status quo. The non-proliferation regime draws its legitimacy from the continuation of extant patterns of power in world politics. Such a static policy cannot succeed forever. Overcoming the threat of nuclear proliferation will require innovative strategy that reaches beyond the status quo. It calls for structural change in the international system to be accomodated instead of resisted. If the Non-Proliferation Treaty is to hold, nuclear weapon states will finally have to forgo their privileged status. This cannot, however, be accomplished simply through the abolition or renunciation of nuclear weapons since nuclear weapons themselves continue to be instrumental for war prevention and international stability. Rather, what is needed is a new approach to the management of the nuclear world system under international responsibility. Nonproliferation and disarmament objectives together call for a concept of global security in which multilateral institutions assume an increasingly important role of nuclear diplomacy. (orig.) [de

  18. Issues of weapons of mass destruction non-proliferation in Tajikistan

    International Nuclear Information System (INIS)

    Mirsaidov, U.M.

    2010-01-01

    This article is devoted to issues of weapons of mass destruction non-proliferation in Tajikistan. Over a period of 20 century, starting from First World War, the weapons of mass destruction arouse serious concern of world community. Geneva protocol of 1925 prohibits the use of chemical and biological weapons. Once nuclear weapon was created, the weapons of mass destruction distributions become the subject of high concern. Besides, during the end of 'cold war', regional conflicts, collapse of Soviet Union, as well as access to sensitive technologies considerably increase the danger of weapons of mass destruction distribution. More than 10 countries have active programs, relating to weapons of mass destruction and, possibly, more than ten countries have potential to start implementing such kinds of programs. Nowadays, trans national organized criminal groups and international terrorist networks are appeared in the world scene, which show interest in obtaining an access to sensitive materials, technologies, weapons and their distribution. After 11 September events, the risk of such weapons of mass destruction components use by such forces for Governments blackmail become real scene, which, despite of low possibility of this threat implementation, could have very serious and disastrous consequences. International community responded to these problems and challenges, basically through the following actions, which is detailed regime development of multilateral international treaties, directed to weapons of mass destruction distribution prevention. Non-proliferation treaty of nuclear weapons, Convention on prohibition of chemical weapons and Convention on prohibition of biological and toxin weapons are some of them. As it is known, Tajikistan signed all these treaties. For different reasons these treaties were subject of serious tests. Nuclear weapons tests in India and Pakistan in 1998 year, actual Israel status as state having nuclear weapon and North Korean program on

  19. An Introduction to Nuclear Non-Proliferation and Safeguards

    International Nuclear Information System (INIS)

    Haakansson, Ane; Jonter, Thomas

    2007-06-01

    The purpose of this project was to compile a course material that covers how the nuclear safeguards system has emerged and how it works today. The produced compendium is directed to both university students and people concerned by safeguards from the industry. The primary aim of the first part of this paper is to describe the historical development of this global non-proliferation system and its central tasks. A second purpose is to discuss the advantages and disadvantages of its current design in order to answer the following question: Can we today say that we have a functioning global non-proliferation system? Does it require further strengthening, and, if so, how can this be achieved? In the second section we review the verification regime within nuclear safeguards, i. e. describe the methods and techniques that are available to reassure the world community that concluded treaties are adhered to

  20. An Introduction to Nuclear Non-Proliferation and Safeguards

    Energy Technology Data Exchange (ETDEWEB)

    Haakansson, Ane; Jonter, Thomas

    2007-06-15

    The purpose of this project was to compile a course material that covers how the nuclear safeguards system has emerged and how it works today. The produced compendium is directed to both university students and people concerned by safeguards from the industry. The primary aim of the first part of this paper is to describe the historical development of this global non-proliferation system and its central tasks. A second purpose is to discuss the advantages and disadvantages of its current design in order to answer the following question: Can we today say that we have a functioning global non-proliferation system? Does it require further strengthening, and, if so, how can this be achieved? In the second section we review the verification regime within nuclear safeguards, i. e. describe the methods and techniques that are available to reassure the world community that concluded treaties are adhered to

  1. Nuclear non-proliferation: Revisiting the basics. Carnegie international non-proliferation conference 2002. Washington, D.C., 14 November 2002

    International Nuclear Information System (INIS)

    ElBaradei, M.

    2002-01-01

    The 1970 Treaty on the Non-Proliferation of Nuclear Weapons (NPT), with 188 States party, represents the cornerstone of the global nuclear non-proliferation and disarmament effort - and despite recent challenges, it has never been more relevant than it is today. But the international community has to move forward, it is essential that a number of the basic assumptions should be revisited, and a number of new approaches reconsidered. A key assumption at the core of the NPT was that the asymmetry between nuclear-weapon States and non-nuclear-weapon States would gradually disappear. The nuclear non-proliferation regime has overall been successful - but with some shortcomings. Efforts to end nuclear weapons development achieved an important milestone with the conclusion of the Comprehensive Nuclear-Test-Ban Treaty (CTBT) in September 1996, but the pace of progress has been sluggish among the 44 countries whose ratification is required for the treaty to enter into force - and the rejection of the CTBT by the US Senate in 1999 was a distinct setback. Negotiation of a Fissile Material Cut-Off Treaty (FMCT) continues to languish in Geneva, more than seven years after agreement was reached on a mandate. The 2000 NPT Review Conference, building on the package of decisions and resolutions that led to the indefinite extension of the NPT in 1995, resulted in a number of encouraging commitments, not least the 'unequivocal undertaking' by the nuclear-weapon States to accomplish the total elimination of their nuclear arsenals. But a scant two years later, we have moved sharply away from those commitments, with a number of the '13 steps' toward nuclear disarmament - such as 'irreversibility,' 'START II, START III and the ABM Treaty,' further 'unilateral' reductions in nuclear arsenals, 'increased transparency,' 'further reduction of non-strategic nuclear weapons,' and 'regular reports' on the implementation of Article VI of the NPT - left without concrete follow-up actions and in

  2. New evolution of safeguards and non-proliferation

    International Nuclear Information System (INIS)

    Seyama, K.; Kurihara, H.

    1999-01-01

    Since the end of the Cold War, circumstances concerning international safeguards and nuclear non-proliferation have changed drastically. At this stage, early introduction of a strengthened and streamlined new safeguards system and broad implementation of the verification activities regarding nuclear material from dismantled nuclear weapons are expected, and in the near future, the international community is expected to establish a verification regime under the Cut Off Treaty. From now on, the roles of the IAEA will become more important in these new areas. At the same time the efficiency of the activities is essential from a financial and human resources aspect in order to introduce those measures smoothly. On the other hand, the Member States should cooperate with the IAEA to improve the transparency of its nuclear policy and activities. Taking account of such circumstances, first, the authors will explain the non-proliferation policy of Japan. Second, the authors will introduce the present status of Japan's safeguards system and activities. Finally, the authors will present several tasks which are important for the IAEA and Japanese safeguards for coming several years. (author)

  3. Non-proliferation

    International Nuclear Information System (INIS)

    Manley, I.T.

    1981-01-01

    Proliferation is a problem that can only be solved when the political problems which lead countries to contemplate, the possession of nuclear weapons are solved; in the meantime it can only be managed. Non-proliferation policy has to deal both with the political and the technical aspects of proliferation. It must seek to buy time by addressing the reasons why nations feel the political need to construct nuclear weapons, as well as delaying the moment when such nations feel capable of doing so. The subject is examined and proposals made. (author)

  4. Carter faces new dilemmas over non-proliferation

    International Nuclear Information System (INIS)

    Dickson, D.

    1979-01-01

    Questions underlying the current domestic debate as to whether the US should revise its attitude towards the relationship between the spread of nuclear energy and the proliferation of nuclear weapons are considered. Problems arising from the provisional conclusions of the International Nuclear Fuel Cycle Evaluation, set up at President Carter's suggestion in 1977, are evaluated. The thorny question of how to deal with the Non-Proliferation Treaty when it comes up for review in 1980 is discussed. Finally there is the issue, for which it is concluded nobody pretends to have all the answers, of whether a sufficient consensus - involving both developed and developing countries as partners in decision-making - can be forged to develop and apply an effective control regime, or whether increasing competition between both producers and consumers of nuclear power will be such as to limit the possibilities for multilateral action, shifting the focus back to bilateral actions. (UK)

  5. Nuclear energy and non proliferation. The role of the International Atomic Energy Agency

    International Nuclear Information System (INIS)

    Cooley, J.; Rauf, T.

    2008-01-01

    This article discusses the role of the International Atomic Energy Agency (IAEA) in the prevention of the spread of nuclear weapons. The IAEA verifies States compliance with their non-proliferation commitments through the application of safeguards on their civilian nuclear programmes to ensure that they are being used solely for peaceful purposes. The IAEA safeguards have evolved in the course of five decades and have become an integral part of the international non-proliferation regime and the global security system. To continue to serve the international community, they need to continue to move with the times, especially in light of the renewed interest in nuclear energy. (Author)

  6. IHEDN-FRS round table - Nuclear non proliferation in front of today's challenges, 10 November 2009 - Vallieres amphitheatre

    International Nuclear Information System (INIS)

    Laborde, Richard; Grand, Camille; Tertrais, Bruno; Champchesnel, Tiphaine de; Hautecouverture, Benjamin; Briens, Martin

    2009-01-01

    This document first proposes a synthetic overview of contributions and then the texts of these contributions. After some introducing speeches, a first set of contributions addressed the present limitations of international instruments of struggle against proliferation (challenges of the 2010 NPT Review Conference, the resolution 1540 of the UN Security Council and the new instruments of struggle against proliferation). The second set of contributions discussed the Iranian and Pakistani cases as examples of proliferation outside of and within the non proliferation regime

  7. The international nuclear non-proliferation system

    International Nuclear Information System (INIS)

    Simpson, J.; McGrew, T.

    1985-01-01

    This volume focuses upon the issues raised at this Conference, and attempts to address the international diplomatic, political and trading, rather than technical, questions which surround nuclear non-proliferation policies. It does so by bringing together chapters contributed by participants in non-proliferation diplomacy, those with experience in shaping International Atomic Energy Agency and national policies and academic observers of non-proliferation activities and the international nuclear industry. An analysis is provided of past non-proliferation policies and activities and current issues, and an attempt is made to offer ideas for new initiatives which may sustain the non-proliferation system in the future

  8. Non-proliferation of nuclear weapons

    International Nuclear Information System (INIS)

    Fischer, D.; Haeckel, E.; Haefele, W.; Lauppe, W.D.; Mueller, H.; Ungerer, W.

    1991-01-01

    During the turbulant transitional events in world politics in the nineties, the control of nuclear weapons plays a major role. While the superpowers are reducing their nuclear arsenal, the danger of nuclear anarchy in the world remains virulent. The NPT of 1968 is up for review soon. The falling apart of the former communist sphere of power, and the regions of conflict in the Third World present new risks for the proliferation of nuclear arms. For unified Germany, which explicitly renounced nuclear weapons, this situation presents difficult questions concerning national safety policies and international responsibility. This volume presents contributions which take a new look at topical and long-term problems of nuclear NP politics. The authors evaluate the conditions under which the NP regime came into being, and assess short- and long-term possibilities and risks. The following papers are included: 1.) Basic controversies during the negotiations concerning the Treaty on non-proliferation of nuclear weapons (Ungerer); 2.) Prologation of the NPT 1995 and appropriate problems concerning safety and control (Haefele/Lauppe); 3.) Consequences of the Iraq case for NP policy (Ficher); 4.) Problems of nuclear technology control (Mueller); 5.) Framework conditions of a nuclear world system (Haeckel). (orig./HP) [de

  9. The NPT regime, present and future global security: an American view

    International Nuclear Information System (INIS)

    Thompson, Sam.

    1987-01-01

    Although not perfect, an international non-proliferation regime as set out by the IAEA and Non-Proliferation Treaty is in existence. The history of the involvement of the United States in the development of this regime is mentioned as a background to explaining the current approach of the Reagan Administration to non-proliferation. Trends and challenges which may affect future global security are then identified and discussed. The author is optimistic about the future. (U.K.)

  10. The EU and non proliferation: need for a quantum leap?

    International Nuclear Information System (INIS)

    Kobia, R.

    2008-01-01

    This paper analyses the possibilities of a strategy and all-encompassing European policy that could constitute an efficient and structured system against proliferation. This paper concentrate on actions and developments at the level of the E.U. sensu stricto, i.e. where common actions under the E.U. umbrella are set up and contribute to the efforts in non-proliferation. It does not cover all measures and mechanisms under the 'non-proliferation regime', the integrated and evolving network of unilateral, bilateral, regional, multilateral treaties and other standing-setting arrangements, which collectively provide a framework guiding the behaviour of states, international organisations, enterprises, associations and all non state actors generally active in the nuclear sector. For the purposes of this paper, the 'utilitarian and teleological' prisms are used. The 'utilitarian perspective aims to maximizing the net expectable utility for all parties affected by a decision or action knowing the that traditional utilitarianism favours the options that bring about the best consequences and aims at the 'good'. The teleological approach lies in an interpretation that favours the ultimate goals of any provision and action as well as their spirit, rather than accepting to remain in a more narrow exegetic interpretation that favours the strict letter thereof. (N.C.)

  11. Nuclear non-proliferation

    International Nuclear Information System (INIS)

    Anon.

    1984-01-01

    DOE's nuclear non-proliferation responsibilities are defined by the provisions of the Atomic Energy Act of 1954, as amended, and of the Nuclear Non-Proliferation Act of 1978 (NNPA). The Department's major responsibilities in this area are to: (1) provide technical assistance to the Department of State in negotiating agreements for civil cooperation in the peaceful uses of nuclear energy with other countries and international organizations; (2) join with other agencies to reach executive branch judgments with respect to the issuance of export licenses by the Nuclear Regulatory Commission; (3) be responsible for processing subsequent arrangements with other agencies as required by the Nuclear Non-Proliferation Act; (4) control the distribution of special nuclear materials, components, equipment, and nuclear technology exports; (5) participate in bilateral and multilateral cooperation with foreign governments and organizations to promote the peaceful uses of nuclear energy; and (6) act as a primary technical resource with respect to US participation in the International Atomic Energy Agency

  12. IAEA Director General welcomes Cuba's intention to join the nuclear Non-Proliferation Treaty

    International Nuclear Information System (INIS)

    2002-01-01

    Full text: IAEA Director General Mohamed ElBaradei welcomed Cuba's announcement to accede to the Treaty on the Non-Proliferation of Nuclear Weapons (NPT) and to ratify the Treaty of Tlatelolco establishing a nuclear-weapon-free zone in Latin America and the Caribbean. He expressed the hope that Cuba will conclude soon a comprehensive safeguards agreement with the Agency, as required under Article III of the NPT. 'With Cuba's intention to become party to the NPT, we have come a step closer to a universal nuclear non-proliferation regime,' Mr. ElBaradei said. Only three countries worldwide with significant nuclear activities now remain outside the NPT. With 188 countries party to the Treaty, the NPT is the most adhered to international agreement after the United Nations Charter and the most widely adhered to multilateral arms control treaty. The NPT makes it mandatory that all non-nuclear-weapon States conclude comprehensive safeguards agreements with the IAEA, and thus put all of their nuclear material under IAEA safeguards. The Director General also welcomed Cuba's ratification of the Tlatelolco Treaty, which completes the process of having all countries in the region of Latin America and the Caribbean as members of the nuclear-weapon-free zone in that region. Mr. ElBaradei said that, 'the Tlatelolco Treaty provides a good model for other regional nuclear-weapon-free zones to follow'. He added that 'universal adherence of all countries in regions having nuclear-weapon-free zone arrangements is important to further strengthen the non-proliferation regime'. (IAEA)

  13. The Puzzle of Non-proliferation and Disarmament (Part II)

    International Nuclear Information System (INIS)

    Ponga, J. de

    2011-01-01

    Since, in 1945, the World was aware of the devastating power of nuclear weapons there have been many initiatives at international level to avoid nuclear weapon proliferation: the foundation of the IAEA, the NPT, the Safeguards Agreements, the Nuclear Weapon Free Zones, the treaties banning nuclear tests or the export control regime of the NSG, among others. This article aims to offer a general picture of all of them as pieces of a puzzle the purpose of which is not to allow gaps to non pacific uses of nuclear energy. (Author)

  14. Non-proliferation and multinational enterprises

    International Nuclear Information System (INIS)

    1979-04-01

    The paper supplements CC/WG.2/9 in presenting the Japanese delegation's contribution in the areas of non-proliferation and multi-national enterprises. The paper questions whether multinational enrichment enterprises would constitute a significant non-proliferation factor, noting that the nature of the venture might create a potential for the dissemination of sensitive information. The paper also argues that a multi-national venture which was not economically competitive (with national facilities) would have questionable viability. The conclusion is that non-proliferation advantages, if any, would be a result, not an objective of such a venture

  15. Nuclear non proliferation and disarmament

    International Nuclear Information System (INIS)

    2000-01-01

    In the framework of the publication of a document on the ''weapons mastership, disarmament and non proliferation: the french action'', by the ministry of Foreign Affairs and the ministry of Defense, the French Documentation organization presents a whole document. This document describes and details the following topics: the conference on the treaty of non proliferation of nuclear weapons, the France, Usa and Non Governmental Organizations position, the threats of the proliferation, the french actions towards the disarmament, the disarmament in the world, a chronology and some bibliographic resources. (A.L.B.)

  16. Preparation for the Nuclear Non-Proliferation Treaty Extension Conference in 1995

    International Nuclear Information System (INIS)

    Chrzanowski, P.L.

    1993-01-01

    About 30 specialists in non-proliferation participated in a workshop to explore ideas for US Government preparatory steps leading to the 1995 Nuclear Non-Proliferation Treaty (NPT) Extension Conference. To that end, workshop sessions were devoted to reviewing the lessons learned from previous Review Conferences, discussing the threats to the non-proliferation regime together with ways of preserving and strengthening it, and examining the management of international nuclear commerce. A fundamental premise shared by workshop participants was that extension of the NPT is immensely important to international security. The importance of stemming proliferation and, more specifically, extending the Treaty, is growing as a result of the significant changes in the world. If the conferees of the Extension Conference decide on no extension or extension for a short limited duration, some technically advanced states that have foregone development of nuclear weapons may begin to rethink their options. Also, other arms control measures, such as the Chemical Weapons Convention, could start to unravel. The US must provide strong international leadership to ensure that the Extension Conference is a success, resulting in Treaty extension, perhaps through successive terms, into the indefinite future. Workshop participants were struck by the urgent need for the US to take organizational steps so that it is highly effective in its advance preparations for the Extension Conference. Moreover, the Extension Conference provides both a challenge and an opportunity to mold a cohesive set of US policy actions to define the future role of nuclear weapons and combat their proliferation

  17. US policies on combating proliferation of nuclear weapons after the cold war

    International Nuclear Information System (INIS)

    Tosaki, Hirofumi

    2005-01-01

    Combating nuclear proliferation has been one of the top priorities for the international community in the post post-Cold War era, and the United States has been taking initiative for tackling the problems. The current Bush administration has placed value high on the effective and concrete actions - including the use of military forces - for such efforts. It is imperative that such actions should be taken in resolving the nuclear proliferation. However, the United States has been criticized that it has disregarded the existing nuclear non-proliferation regime, and that its non-proliferation policy has given negative implications to the regime. Combating nuclear proliferation should be pursued in balanced approach with legitimacy, in consideration of the discriminately nature of the regime as well as of its three pillars - nuclear non-proliferation, nuclear disarmament and peaceful use of nuclear energy. (author)

  18. The European dimension in non-proliferation

    International Nuclear Information System (INIS)

    Krause, J.

    1996-01-01

    Europe was for decades the focal point of efforts to prevent or constrain nuclear proliferation and the first region in which non-proliferation efforts failed. Paper deals with current proliferation problems in Europe, namely, diversion of weapons, diversion from dismantling, production over-capacity, security concerns. Legal instruments against proliferation in Europe described here include development of international norms; instruments of security assurance and cooperation; disarmament assistance; fissile material management; assistance in creating export control systems; improving and harmonizing export controls for dual-purpose items. Problems in implementing non-proliferation instruments are described separately

  19. Romania non-proliferation policy

    International Nuclear Information System (INIS)

    Biro, Lucian; Grama, Viviana

    2001-01-01

    is a component of the National Development Strategy for Romania, presented to the European Union, as a main step in the accession process. Cernavoda NPP Unit 1 is in commercial operation from 1996 and assures 10% of the overall national electricity production. Cernavoda Unit 2 is now about 40% complete, and the Government of Romania has declared its completion as a national priority. The national participation in this project planned to be completed by the year 2005 comprises important contribution of the nuclear infrastructure developed in Romania for the CANDU power plants. Physical Protection of Nuclear Material is also regarded as a fundamental element of the non-proliferation regime. Physical Protection comprises those measures that Romania apply to prevent or deter illegal actions taken against nuclear facilities and nuclear materials, particularly when such materials, are transported across the country. Romania received IAEA assistance to enhance its efforts to prevent unclear material and other radioactive sources from being use illegally and to detect and respond to trafficking cases, should they occur. This assistance included an IPASS Mission and training for staff involved in physical protection for nuclear material and nuclear installations. In 1993 Romania ratified the Convention on Physical Protection of Nuclear Material and has following requirements for nuclear material transport: the material must be classified according to its characteristics, the material may be transported only in approved containers, containers must be marked with safety labels or placards to indicate their contents, for certain radioactive material the shipper must have in place an emergency response assistance plan. CNCAN coordinates at national level the activities regarding preventing and combating illicit trafficking with nuclear materials. From 1993 when the IAEA database was installed, Romania reported 22 incidents involving nuclear material and radioactive sources. In

  20. Israel's position on non-proliferation

    International Nuclear Information System (INIS)

    Marom, R.

    1986-01-01

    Israel maintained that the complex international system and worldwide political tension created a situation in which comprehensive plans of disarmament could not produce any positive result. The deadlock in the field of general and complete disarmament has brought Israel to the realization that one possible way to alleviate the stalemate could be progress by stages through partial measures of disarmament. Israel's position on non-proliferation indicates that the establishment of a nuclear-weapon-free-zone (NWFZ), as it relates to the Middle-East, could serve as a credible alternative to the unilateral adherence to the Non-Proliferation of Nuclear Weapon (NPT) and an effective measure of non-proliferation in the region. (Author)

  1. Non-proliferation and advances in nuclear science

    International Nuclear Information System (INIS)

    Iyengar, P.K.

    1995-01-01

    So far, the non-proliferation treaty (NPT) has concentrated on safeguard regimes based on technologies relating to the production of uranium and plutonium in nuclear reactors, and on their potential diversion for use in nuclear weapons. As nuclear science advances, however, nuclear technology both peaceful and for weapons will change, and for the NPT to remain relevant, it must reflect these changes. At this juncture, when the NPT is coming up for review in a year's time, it is important for physicists to take a fresh look at recent advances in nuclear science, and inform the policy-makers and the public at large about their potential for impacting nuclear technology in the future. In this article a few such advances are highlighted and their implications for the NPT are considered. (author). 4 refs

  2. Proliferation studies for different radiotherapy fractionation regimes

    International Nuclear Information System (INIS)

    Jones, L.

    1996-01-01

    Full text: This study was undertaken to investigate extended treatment schedules and compare the differences between schedules for highly proliferative tumours. Treatment schedules can be extended for various reasons e.g. public holidays, early side effects. For highly proliferative tumours this can dramatically reduce the effective dose delivered to the tumour. To deduce the most effective schedule fractionation regimes are compared to a common schedule so that the effects can be understood. Thus an equation to allow this to be done for the proliferative case has been derived. (i) The linear quadratic model with proliferation has been used to investigate the effect on biological effective dose (BED) when treatment schedules are extended. (ii) An equation was derived for comparison with a standard effective dose (SED) of 2Gy/fraction given daily 5 days per week, this is a common schedule in most radiotherapy centres. The SED equation derived for the proliferative case is where n 1 and n 2 are the number of fractions for the initial and equivalent schedules respectively, d 1 is the dose delivered per fraction for the initial schedules. T 1 is the time taken for the initial schedule (in days) and T p is the proliferation half life for the tumour involved. SEDs were calculated for the CHART regime of 36 fractions at 1.5 Gy in 12 days (Saunders et al. 1988, cited in Fowler J F, Brit. J. Radiol. 62: 679-694, 1989) and various other schedules. Late effects of these schedules and their standard equivalents were compared. The dose required to achieve the same BED when a treatment schedule is extended has been found to be quite large in some circumstances. For breast tumours a loss of 2Gy 10 BED to tumour occurs after ten days extension of treatment time (T p =12 days,T k =12 days). For head and neck tumours a loss of 2Gy 10 BED occurs after only three and a half days (T p =3 days). From these results it seems that an accelerated fractionation schedule would be advantageous

  3. Non-proliferation of nuclear weapons: The road ahead. London, 15 January 2001

    International Nuclear Information System (INIS)

    ElBaradei, M.

    2001-01-01

    The document reproduces the text of the conference given by the Director General of the IAEA at the Royal Institute of International Affairs in London, 15 January 2001. The Director General points out that for over five decades since the summer of 1945, strategies of national and international security have been intertwined with the concept of nuclear weapons as a strategic deterrent. In his view, the achievement of a nuclear weapon free world will crucially depend on a fundamental change in that concept of 'security'. Besides the historical perspectives the paper focuses on the non-proliferation and nuclear disarmament strategies. The Director General also states that to achieve the main goal of universal non-proliferation and disarmament it is indispensable to re-evaluate nuclear weapon states status; challenge the doctrine of nuclear deterrence; develop alternatives to nuclear deterrence; and engage in constructive dialogue. In conclusion it is re-emphasized that there remain both the difficulties and the opportunities of the road towards nuclear disarmament. It is pointed out that construction of a non-proliferation regime with near-universal participation has been successful and some progress towards nuclear disarmament has been achieved, but several goals must be pursued to maintain and build upon achievements

  4. Physical protection and its role in nuclear non-proliferation

    International Nuclear Information System (INIS)

    Nilsson, A.

    1999-01-01

    Non-proliferation of nuclear weapons has been one of the main concerns of the international community since the first nuclear weapons were developed. To prevent the proliferation of nuclear weapons has been on the agenda for individual States, groups of States and the international organizations. A number of treaties, conventions and agreements, the most important being the Non-Proliferation Treaty, have been negotiated to prevent the horizontal proliferation of nuclear weapons. States have concluded safeguards agreements with the IAEA to fulfill their obligations according to Article III.1 of the NPT. Other agreements relate to the prevention of vertical proliferation and also to the disarmament of nuclear weapons. It has also been recognized that sub-national, terrorist, or criminal activities may pose a proliferation risk. Illicit trafficking of nuclear material, particularly highly enriched uranium or plutonium, is a non-proliferation concern. States have recognized the need to prevent, as far as possible, the use of nuclear material in unlawful activities. The Convention of Physical Protection of Nuclear Materials, obligates the State Parties to protect nuclear material from theft during international transport, and to make unlawful possession, use, etc., of nuclear material a criminal offense, subject to punishment under national law. Although the physical protection convention recognizes the importance of the physical protection of nuclear material in domestic use, storage and transport, it does not obligate the State party to establish the necessary systems for this purpose. It is this limitation which led many States to believe that the international physical protection regime needs to be strengthened. Although not legally binding per se, the recommendations documented in INFCIRC/225/Rev. 4, The Physical Protection of Nuclear Material and Nuclear Facilities, has obtained wide recognition. There is recognition among States that protecting nuclear material

  5. China's position on nuclear non-proliferation

    International Nuclear Information System (INIS)

    Qian Jiadong.

    1986-01-01

    The paper discusses China's position on nuclear non-proliferation, in view of the fact that China does not subscribe to the Non-Proliferation Treaty (NPT). China refuses to accede to the NPT because it considers the treaty to be discriminatory, and reasons are given for this point of view. However its stand for nuclear disarmament and disapproval of nuclear proliferation are declared. Nuclear arms race, prevention of nuclear war, and nuclear disarmament are also considered. (UK)

  6. Abstracts of 3. International scientific-practical conference 'Semipalatinsk Test Site. Radiation Legacy and Non-proliferation Issues'

    International Nuclear Information System (INIS)

    2008-01-01

    The Conference gathered representatives of more than 25 countries and international organizations. In the Conference among with actual problems of current environment conditions in Kazakhstan, perspective trends in the field of radiation protection, radio-ecological and radiobiological research and issues of international co-operation in support of non-proliferation regime, other advanced scientific projects were considered [ru

  7. Nuclear non proliferation. Challenges after the NPT extension - CERI Studies Nr 11

    International Nuclear Information System (INIS)

    Delpech, Therese

    1996-01-01

    After the decision of extension of the Non Proliferation Treaty (NPT) in May 1995, the author first discusses strengths and weaknesses of the non proliferation regime. On the one side, the five nuclear powers are tight by international commitments, the number of proliferating countries has not increased, some countries have willingly decided to give up their military nuclear programme, ex-USSR republics have joined the NPT, the Israel-PLO agreement of 1993 initiated a new era, potentially proliferating countries do not have very significant nuclear programmes, shortcomings of international controls have been identified, international cooperation has improved, and control techniques are available. On the other hand, some matters of concern remain: lessons from the Gulf War, an apparently easier access to nuclear weapons, new opportunities of regional domination, a weaker American guarantee, the North-Korean problem, new exporters of nuclear and ballistic goods and technologies. In the next part, the author discusses the conditions of the agreement for an undefined extension of the NPT, and notably outlines what made this success possible. Then, she addresses political issues related to the universal character of the NPT and to nuclear disarmament. She also discusses the responsibility of the Five nuclear powers, the role of nuclear weapons, and the implication of the extension of the Treaty for the European Union

  8. Nuclear exports and non-proliferation

    International Nuclear Information System (INIS)

    Courteix, Simone.

    1978-01-01

    Increased preoccupation in present times with the risk of proliferation of nuclear weapons is reflected in the multiplication of international agreements such as the Non-proliferation Treaty and in the strengthening of consultations between industrialised countries (London Club). After analysing the IAEA safeguards system under the Non-proliferation Treaty and its shortcomings both technically and otherwise, the author considers how this situation can be remedied in the light of the London Agreements and in view of the position of the main countries concerned. The annex to the book contains the texts of many international agreements and relevant national regulations as well as nuclear policy statements. It also includes a detailed bibliograaphy. (NEA) [fr

  9. Non-proliferation

    International Nuclear Information System (INIS)

    Deiseroth, D.; Gustafsson, S.

    1993-01-01

    The issue of Nuclear Non Proliferation has been moved to a leading place on the contemporary international security agenda. What about the situation of nuclear weapons and nuclear technology in Russia, Kazakhstan, Ukraine and Belorussia? Why did the IAEA-inspectors totally failed to discover any sign of Iraq's clandestine nuclear-weapon programme before the Gulf War? Do the NATO and their nuclear power states violate Art. VI of the Non-Proliferation-Treaty (NPT), because they are - despite the end of the cold war - not willing to renounce of the ''option of the first use of nuclear weapons''? Does the NPT establish a form of nuclear apartheid? What will be the situation if the NPT-Extension-Conference in 1995 will be unable to obtain a majority of the parties for any one extension proposal? Do we need a new international nuclear control agency with severe powers, a sort of nuclear Interpol? The Colloquium ''Saving NPT and abolishing Nuclear Weapons'', held in Stockholm in September 1992, organized by the Swedish and the German Sections of IALANA, tried to analyse some of the raised issues. (orig.) [de

  10. The future of non-proliferation

    International Nuclear Information System (INIS)

    Gere, F.

    2000-01-01

    This paper comprises two parts. The first part makes a status of the non-proliferation policy: problems of ratification of Start 2 and CTBT treaties, nuclear tests in India and Pakistan in May 1998 etc. The second part makes a prospective reflexion on the evolution of the position of nuclearized countries at the 2015-2030 vista: role of Asia, nuclear perception, evolution of the US perception of non-proliferation, military strategy and European unification. (J.S.)

  11. Post-Cold War Effects on the Non-proliferation Regime

    Energy Technology Data Exchange (ETDEWEB)

    Kessler, Carol E.

    2006-03-31

    This journal article analyzes nuclear and security related events of the past 15 years to illustrate the changes in geopolitics and the shifting balance of power following the collapse of the Soviet Union. Reflection upon these events establishes the context for strengthening the nonproliferation regime. The author concludes that post Soviet communism hastened the movement towards a unipolar system with hegemonic power vested in the United States, and this geopolitical imbalance fostered insecurities and greater threats. Multilateral cooperation and commitment from the US would help this leader achieve its goal of security through increased global confidence in the international system.

  12. Putting teeth in the nuclear non-proliferation and disarmament regime. 25 March 2006, Karlsruhe, Germany

    International Nuclear Information System (INIS)

    ElBaradei, M.

    2006-01-01

    The factors, contributing to the world's changes in respect to peace, security and non-proliferation of nuclear weapons are presented in the document. Five necessary and urgent measures are proposed in order to meet the current challenges: 1)tighten control for assess to nuclear fuel cycle technology; 2)accelerate global efforts tp protect nuclear material; 3)support effective nuclear verification; 4) reinvigorate disarmament efforts; 5) increase the effectiveness of the UN Security Council. The importance and necessity to place nuclear operations under multinational control is outlined

  13. The Asian countries and the non-proliferation treaty prorogation

    International Nuclear Information System (INIS)

    Hoffmann, N.

    1995-01-01

    This work deals with the non-proliferation treaty prorogation of Asia. The position of the asian countries under the old non-proliferation treaty is given. It includes the 1968 non-proliferation treaty signatories, the calling in question again and the criticisms revealed by the asian countries. The positions and the open forecasts expressed on the non-proliferation treaty prorogation and the article on the elimination of the nuclear weapons are also given. (O.L.)

  14. Lessons from post-war Iraq for the international full-scope safeguards regime

    International Nuclear Information System (INIS)

    Scheinman, L.

    1993-01-01

    The discovery after the Gulf War of the extensive Iraqi nuclear weapon program severely shook public confidence in the nuclear non-proliferation regime in general, and the safeguards program of the IAEA under the nuclear Non-Proliferation Treaty, in particular. Iraq provided the justification for evaluating the safeguards regime under new political circumstances, so that appropriate corrective measures could be taken when necessary. It is now up to the individual states within the international system to take advantage of this opportunity

  15. Non proliferation 1980 - INFCE and TnP

    International Nuclear Information System (INIS)

    Rainer, R.

    1981-01-01

    The TNP (non-proliferation agreement of nuclear weapons), its non proliferation policy and the peaceful use of fuel cycle are described, as well as the safeguards of IAEA. It is also mentioned the functions of INFCE (International Nuclear Fuel Cycle Evaluation). (A.B.T.) [pt

  16. Germany and the nuclear non-proliferation; Current situation and prospects; Deutschland und die nukleare Nichtverbreitung; Zwischenbilanz und Ausblick

    Energy Technology Data Exchange (ETDEWEB)

    Preisinger, J.

    1993-07-01

    A summary is given of the consequences, both positive and negative, of international non-proliferation policy. The numerous, complex branches and connections of national measures and inter-stake agreements for the peaceful, controlled uses of nuclear technology and related military technologies are expertly described, and assessed on their effectiveness. Weak aspects of the nuclear non-proliferation regime are pointed out and past reforms are illustrated and assessed in the light of recent developments. The interests of the German Federal Republic from the centre of this analysis. The author shows that, after a certain hesitary, German diplomacy has now become active in the establishment of an international non-proliferation regime. He concludes that Germany should take a strong initiative role in maintaining a peaceful international nuclear order. (orig.) [Deutsch] Es wird ein Resuemee der bisherigen Erfolge und Misserfolge internationaler Nichtverbreitungspolitik gezogen. Die komplexen, vielfach veraestelten und verschachtelten nationalen Massnahmen und zwischenstaatlichen Vereinbarungen zur Ueberwachung und friedlichen Zweckbindung von Nukleartechnologie und militaerisch relevanten Anschlusstechnologien werden sachkundig erlaeutert und auf ihre Wirksamkeit ueberprueft. Schwachstellen des nuklearen Nichtverbreitungsregimes werden offengelegt, Reformschritte der vergangenen Jahre werden dargestellt und im Lichte der juengsten Entwicklungen bewertet. Dabei steht die Interessenlage der Bundesrepublik Deutschland im Zentrum der Analyse. Der Autor zeigt, dass die deutsche Diplomatie sich nach einer gewissen Zurueckhaltung schliesslich aktiv in die Gestaltung des internationalen Nichtverbreitungsregimes eingeschaltet hat. Er plaediert fuer eine kraftvolle Initiativrolle Deutschlands zur Erhaltung einer friedlichen internationalen Nuklearordnung. (orig.)

  17. The global non-proliferation and disarmament regime. Challenges and prospects for the future. Interview with Mr. Ambassador Jayantha Dhanapala, President of the Pugwash Conferences on Science and World Affairs, November 26, 2009

    International Nuclear Information System (INIS)

    Hautecouverture, Benjamin

    2009-01-01

    President of the Pugwash Conferences on Science and World Affairs since November 2007, Mr. Jayantha Dhanapala has had a long career as a Sri Lankan diplomat and leader in the field of international security. Among his numerous appointments, Mr. Dhanapala headed the Geneva-based UNIDIR. He chaired the widely acclaimed 1995 NPT Review and Extension Conference. He was Under-Secretary-General for Disarmament Affairs in the United Nations from 1998 to 2003. In this interview, Mr. Dhanapala gives us his thoughts about the nuclear non-proliferation regime, a few months before the 8. NPT Review Conference. (author)

  18. The 50 Years of Safeguards and Non-Proliferation in Poland

    International Nuclear Information System (INIS)

    Pawlak, A.; Jurkowski, M.; Zagrajek, M.

    2015-01-01

    Milestones of safeguards and non-proliferation activities are presented. Poland has declared its compliance with non-proliferation regime by ratification of Treaty of Nonproliferation of Nuclear Weapons in 1969. Poland concluded in 1972 Agreement with IAEA for application of safeguards — INFCIRC/153. Next steps in implementation of international safeguards were: ratification of Additional Protocol and introduction of Integrated Safeguards. After accession to European Union, Poland fulfils its safeguards obligations according to following international legal instruments: Treaty establishing Euratom, Agreement between Poland, European Commission and International Atomic Energy Agency in connection with implementation of Article III of Treaty of Non-proliferation of Nuclear Weapons — INFCIRC/193 and Additional Protocol to this Agreement — INFCIRC/193 Add.8. Detailed safeguards requirements are established by domestic Act of Parliament of 29th November 2000 — Atomic law and European Union's Regulations of Commission (Euratom) No 302/2005 on application of Euratom safeguards and the Commission Recommendation on guidelines for the application of Regulation (Euratom) No 302/2005. SSAC was established in 1972 as required by CSA. Activities related to accounting for and control of nuclear material were conducted from 1970s till 1990s by Central Laboratory for Radiological Protection and National Inspectorate for Radiation and Nuclear Safety. Currently, NAEA is responsible for collecting and maintenance of accounting data and safeguards inspections at all MBAs. Around 30 routine inspections/year are performed by the NAEA, Euratom and IAEA. In addition, usually 2 unannounced inspections/year under framework of Integrated Safeguards are conducted. In accordance with implementation of Global Threat Reduction Initiative seven shipments of high enriched nuclear fuel from research reactor to Russian Federation under supervision of safeguards inspectors from NAEA

  19. Supporting non proliferation and global security efforts

    International Nuclear Information System (INIS)

    Pochon, E.

    2013-01-01

    CEA contributes as a major actor of France's action against nuclear proliferation and to the strengthening of nuclear security at national level as European and International levels, in particular through the support of the IAEA activities in nuclear non proliferation with the French Support Programme for the IAEA safeguards system and security with the contribution to the IAEA Nuclear Security Plan and cooperation projects with the European Commission. The CEA is a French government funded technological research organization, organized around 5 branches: Nuclear Energy, Technological Researches, Defence (DAM), Material Sciences and Life Sciences. Within the scope of its activities, CEA covers most of the research areas and techniques in nuclear non-proliferation and security. The CEA is also the advisor of the French Government on nuclear policy. Treaty monitoring and the development and implementation of non proliferation and global security programs is an important mission of DAM which rely on nuclear weapons manufacture and past testing experience. The programmes on non proliferation and global security carried out to fulfil DAM's mission cover the following areas: development of monitoring and detection methods and equipments, country profiles and nuclear stockpiles assessment, arms control instruments, proliferation resistance of nuclear fuel cycle, monitoring of nuclear tests, operation and maintenance of national detection capabilities and contribution to CTBT verification systems. (A.C.)

  20. Nuclear Society and non-proliferation problems

    International Nuclear Information System (INIS)

    Gagarinskij, A.Ya.; Kushnarev, S.V.; Ponomarev-Stepnoj, N.N.; Sukhoruchkin, V.K.; Khromov, V.V.; Shmelev, V.M.

    1997-01-01

    In the USSR Nuclear Society in 1991 the special working group on the problems of nuclear weapons non-proliferation and nuclear materials control, uniting the experts of different types (nuclear physicists, lawyers, teachers), was created. This group became the mechanism of the practical Nuclear Society activity realization in this sphere. Three milestones of the innovative activity can be specified. First Milestone. In January 1992 the Central Nuclear Society Board (of the International Public Nuclear Society Association) published a special appeal to the First Leaders of all countries - former USSR republics. This address paid a special attention to the unity of the USSR power-industrial complex, and numerous problems arisen while separating this complex, including nuclear weapons non-proliferation problems, were indicated as well. Second Milestone. In 1992 and 1993 the Nuclear Society experts issued two selection 'Nuclear Non-proliferation and Control Problems' including reviewing basic papers. In addition, materials on non-proliferation and control are published regularly in the organs. Third Milestone.In 1993 - 1997 some special scientific and technical events (conferences, workshops, meetings) allowing to analyze the joint international projects and contracts outcomes, and establish new contacts between the specialists of NIS, Baltic states and others, have been hold

  1. Canada and international safeguards. Verifying nuclear non-proliferation

    International Nuclear Information System (INIS)

    1990-01-01

    The Non-Proliferation Treaty (NPT) came into force in 1970 and now has about 140 signatory nations. By creating legal barriers against proliferation and by promoting an international non-proliferation ethic, the NPT has promoted international peace and security. A key ingredient has been the confidence generated through verification by IAEA safeguards. By the end of 1988 IAEA safeguards agreements had been concluded with about 100 countries, including Canada. Over 500 nuclear facilities worldwide are under safeguards or contain safeguarded nuclear material. The existence of this credible and effective safeguards system makes international trade in nuclear equipment and materials possible, monitoring the transfer of nuclear technology to developing countries as well as between industrial countries. Canada is committed to non-proliferation and IAEA safeguards. Canadian non-proliferation policy is among the strictest in the world, even though opportunities have been lost to sell Canadian technology abroad as a result

  2. United States non-proliferation policy

    International Nuclear Information System (INIS)

    Scheinman, L.

    1978-01-01

    U.S. non-proliferation policy is aimed at slowing the spread of nuclear weapons capabilities, managing the destabilizing effects of nuclear technology for energy purposes, and fostering international standards and institutions to deal responsibly with global nuclear development. These goals assume that nuclear technology has not already precluded social control and recognize the social benefits offered by peaceful uses of atomic energy. Non-proliferation policies recognize that the motivation for possessing nuclear weapons is a more-difficult problem than technical ability and will concentrate on reducing those incentives through international agreements and safeguards and by maintaining the separation of commercial nuclear fuel cycles and military uses

  3. Non-proliferation and security: synergy and differences

    International Nuclear Information System (INIS)

    Joly, J.

    2013-01-01

    Operators of nuclear facilities put in place both physical and organisational means to meet in a comprehensive way the requirements associated with Nuclear Non-Proliferation, Safety and Security. The common aim is to protect man and the environment from ionising radiation. The approaches for meeting these requirements have real similarities, but also differences which need to be respected in order to develop an appropriate synergy for obtaining the best possible level of safety, security and non-proliferation. This article aims to show the provisions that have been taken with regard to non-proliferation, security and safety which complement and reinforce each other.The paper is followed by the slides of the presentation. (author)

  4. Nuclear proliferation: present, past and future

    International Nuclear Information System (INIS)

    Alonso, M.; Zaleski, P.

    1993-01-01

    Since the end of WW II one of the more, if not the most, serious concerns of all people in the world has been to preserve this planet avoiding a nuclear war. On the positive side, in spite of the huge arsenal of strategic and tactical nuclear weapons (NW) accumulated over the years by the US and the former SU and the innumerable military conflicts we have witnessed since WW II, no NW have been used again. But this should not be a great consolation: the fact that countries have refrained from using NW does not necessarily mean that it will always be that way. As long as countries try to solve their differences by the use of force the danger of a nuclear confrontation remains, and nuclear disarmament and proliferation should cotinue to be a serious concern. This concern has profound political, social and ethical components that have been analyzed extensively and profusely. The purpose of this paper is more limited: to provide an overview of the national and international efforts to minimize the risk of a nuclear war by regulating, restricting and containing the development and possession of NW. This is what has become know as the nuclear non-proliferation regime. Any nuclear non-proliferation regime must have two essential goals: achieving nuclear disarmament by the NWS (and thereby eliminating vertical proliferation). To make a regime effective it must rely on international agreements, a system of safeguards coupled with inspection and verification procedures, and above all on the good faith of all nations involved. It should be stated from the very beginning that nuclear non-proliferation efforts, like all disarmament efforts, are essentially of political nature, albeit having an important scientific and technological component. They are effective only to the extent that countries really renounce NW and are prepared to severely sanction those who do not. (Author) 31 refs

  5. Remote sensing and geoinformation technologies in support of nuclear non-proliferation and arms control verification regimes

    Energy Technology Data Exchange (ETDEWEB)

    Niemeyer, Irmgard [Forschungszentrum Juelich GmbH, Institut fuer Energie- und Klimaforschung, IEK-6: Nukleare Entsorgung und Reaktorsicherheit (Germany)

    2013-07-01

    A number of international agreements and export control regimes have been concluded in order to reduce the risk and proliferation of weapons of mass destruction. In order to provide confidence that Member States are complying with the agreed commitments, most of the treaties and agreements include verification provisions. Different types of verification measures exist, e.g. cooperative measures; national technical means; technical monitoring or measurement devices placed at or near sites; on-site inspections; intelligence information; open-source information, such as commercial internet data and satellite imagery. The study reviews the technical progress in the field of satellite imaging sensors and explores the recent advances in satellite imagery processing and geoinformation technologies as to the extraction of significant observables and signatures. Moreover, it discusses how satellite data and geoinformation technologies could be used complementary for confirming information gathered from other systems or sources. The study also aims at presenting the legal and political aspects and the cost benefits of using imagery from both national and commercial satellites in the verification procedure. The study concludes that satellite imagery and geoinformation technologies are expected to enhance the verification efficiency and effectiveness.

  6. Regime change?

    International Nuclear Information System (INIS)

    Pilat, Joseph F.; Budlong-Sylvester, K.W.

    2004-01-01

    Following the 1998 nuclear tests in South Asia and later reinforced by revelations about North Korean and Iraqi nuclear activities, there has been growing concern about increasing proliferation dangers. At the same time, the prospects of radiological/nuclear terrorism are seen to be rising - since 9/11, concern over a proliferation/terrorism nexus has never been higher. In the face of this growing danger, there are urgent calls for stronger measures to strengthen the current international nuclear nonproliferation regime, including recommendations to place civilian processing of weapon-useable material under multinational control. As well, there are calls for entirely new tools, including military options. As proliferation and terrorism concerns grow, the regime is under pressure and there is a temptation to consider fundamental changes to the regime. In this context, this paper will address the following: Do we need to change the regime centered on the Treaty on the Nonproliferation of Nuclear Weapons (NPT) and the International Atomic Energy Agency (IAEA)? What improvements could ensure it will be the foundation for the proliferation resistance and physical protection needed if nuclear power grows? What will make it a viable centerpiece of future nonproliferation and counterterrorism approaches?

  7. Rogue proliferator? North Korea's nuclear fuel cycle and its relationship to regime perpetuation

    International Nuclear Information System (INIS)

    Habib, Benjamin

    2010-01-01

    North Korea is unlikely to relinquish its nuclear program because of its importance to the perpetuation of the Kim regime. This conclusion arises from the observation that the nuclear program has been a long-term project spanning several decades, culminating in denuclearisation negotiations, which have followed a cyclical pattern in which the North has provoked crises to extract concessions and gain leverage vis-a-vis regional states. It is clear that the nuclear program has great intrinsic value to Pyongyang. First, this paper argues that the sunk costs of previous investment in the nuclear program, as evidenced by the infrastructure for the country's nuclear fuel cycle, create forward momentum favouring continuation of the nuclear program. Second, it argues that the nuclear program solidifies Kim regime rule as an institutional buttress, as a prop for the domestic economy, and as a vehicle for ideological legitimation. The paper is a unique contribution, which explicitly links the Kim regime's proliferation calculus to the economic and bureaucratic imperatives of regime perpetuation, as well as the sunk cost of previous investment in the nuclear program. It provides a coherent explanation for North Korea's consistent unreliability in negotiations, and offers insights into future prospects of the denuclearisation process.

  8. Elements of safety and non proliferation

    International Nuclear Information System (INIS)

    Jalouneix, Jean; Aurelle, Jacques; Funk, Pierre; Ladsous, David; Bon Nguyen, Romuald; Goue, Georges; Lefevre, Odile

    2015-01-01

    This book on nuclear safety and non proliferation is based on knowledge and expertise of the IRSN. The first chapter addresses the safety of nuclear materials, of their installations and of their transportations. It proposes some contextual elements, presents the general guidelines of the French nuclear safety arrangement, the approach to take risks into account, the involved governmental and public bodies, the legal framework, and the protection and control arrangement (in terms of planning of safety-related activities, in terms of operator obligations, in terms of exercises and management crisis). The second part addresses the safety of radioactive sources: context (peculiarity, losses and thefts), international framework (source categories, Euratom directive), and the French organisation. The third chapter addresses nuclear non proliferation: historical background (creation and role of the IAEA and of the EAEC, definitions), principle of statements, inspection process, and French organisation (legal framework, governmental bodies, the IRSN). The last chapter addresses the issue of chemical non proliferation: historical background, international context (Convention on chemical weapons, organisation for their ban), and the French organisation

  9. The treaty on the non-proliferation of nuclear weapons and the process for its enhanced review on the eve of the 2000 review conference

    International Nuclear Information System (INIS)

    Pinel, C.

    2000-01-01

    This article sets out the principle and essentials of the process for reviewing the operation of the non-proliferation treaty (NPT). The NPT was opened for signature on 1 July 1968 and came into force on 5 March 1970. In 1995 the NPT was extended. The 2000 review conference is of considerable importance for the future of the nuclear non-proliferation regime, particularly in the light of the fact that after the indefinite and unconditional extension of the treaty, the non-nuclear-weapon states urged the nuclear-weapon states to take new steps towards nuclear disarmament. This article presents a review of the 30 year period of the application of NPT

  10. The non-proliferation policies of non-nuclear-weapon states

    International Nuclear Information System (INIS)

    Marwah, Onkar

    1987-01-01

    Eight countries are considered to be capable of producing nuclear weapons and highly suspect in their intentions to actually produce them. These are Argentina, Brazil, India, Pakistan, Israel, South Africa, the Republic of Korea and Taiwan. The policies of these suspect Non-nuclear-weapon States (NNWS) are considered in this paper. The first part assesses the non-proliferation (or proliferation) policies of the eight suspect NNWS, the second part evaluates their differences in approach from the policies urged upon them by the nuclear-weapon states (NWS) and the third and final part attempts to understand the future evolution of NNWS policies in the nuclear military field. (U.K.)

  11. IAEA safeguards and non-proliferation

    International Nuclear Information System (INIS)

    Harry, R.J.S.

    1995-02-01

    An overview is given of the efforts to contain the nuclear weapons proliferation during half a century of man-controlled nuclear fission. An initial policy of denial did not work, a following period of cooperation needed a gradual strengthening of international assurances on the exclusively peaceful character of the flourishing use of nuclear techniques for power generation and of other applications. The focus of the nuclear weapon proliferation concern changed from the highly developed states to developing states. The Non-Proliferation Treaty laid the basis for a unique system of voluntarily accepted international inspections to verify the peaceful use of nuclear energy. The IAEA got the task to implement this 'Full Scope Safeguards' on all nuclear material and all nuclear activities in the non-nuclear weapon states. Thanks to the structure of the IAEA, in which both proponent and states with a critical attitude take part in the decision making process on the IAEA execution of its tasks, a balanced, and widely acceptable system emerged. International developments necessitated additional improvements of the non-proliferation system. The increase of strength of sub-national groups triggered international cooperation on physical protection, about a quarter of a century ago. More recently, it appeared that NPT states with assumed nuclear weapon ambitions operated in the margins between the interpretation of IAEA safeguards and the spirit and purpose of NPT. Improvements of the IAEA safeguards and a stronger cooperation between states, including the constraints which exporting states have imposed on nuclear supplies, strengthen the safeguards system. The important reductions in the two largest nuclear weapon arsenals lead, together with the delay in the fast breeder implementation, to large stockpiles of nuclear weapon usable materials. Also in this areas new internationally credible assurances have to be obtained, that these materials will never return to nuclear

  12. IAEA safeguards and non-proliferation

    Energy Technology Data Exchange (ETDEWEB)

    Harry, R J.S.

    1995-02-01

    An overview is given of efforts to contain the nuclear weapons proliferation during half a century of man-controlled nuclear fission. An initial policy of denial did not work, a following period of cooperation needed a gradual strengthening of international assurances on the peaceful character of the flourishing use of nuclear techniques for power generation and of other applications. The focus of the nuclear weapon proliferation concern changed from the highly developed states to developing states. The Non-Proliferation Treaty laid the basis for a unique system of voluntarily accepted international inspections to verify the peaceful use of nuclear energy. The IAEA got the task to implement this `Full Scope Safeguards` on all nuclear material and all nuclear activities in the non-nuclear weapon states. Thanks to the structure of the IAEA, in which both proponent and states with a critical attitude take part in the decision making process on the IAEA execution of its tasks, a balanced, and widely acceptable system emerged. International developments necessitated additional improvements of the non-proliferation system. The increase of strength of sub-national groups triggered international cooperation on physical protection, about a quarter of a century ago. More recently, it appeared that NPT states with assumed nuclear weapon ambitions operated in the margins between the interpretation of IAEA safeguards and the spirit and purpose of NPT. Improvements of the IAEA safeguards and a stronger cooperation between states, including the constraints which exporting states have imposed on nuclear supplies, strengthen the safeguards system. The important reductions in the two largest nuclear weapon arsenals lead, together with the delay in the fast breeder implementation, to large stockpiles of nuclear weapon usable materials. Also in this areas new internationally credible assurances have to be obtained, that these materials will never return to nuclear weapon applications.

  13. Non-proliferation and disarmament

    International Nuclear Information System (INIS)

    Ritter von Wagner, A.

    1993-01-01

    In 1995 the Conference on the prolongation of the Non-Proliferation Treaty will take place. Will it be extended for a long term, indefinitely or only for a fixed period? The Federal Government of Germany advocates an unlimited extension of the Non-Proliferation Treaty. Others have different ideas alleging that the Treaty is imperfect and discriminating. It is a thorn in the side of many States, in particular of the Third World, which no longer want to put up with being treated as second-class states. One argument which is considered especially embarrassing by developing countries as a visible expression of such discrimination, are the nuclear tests which are still carried out by nuclear weapon states. Is the political situation still such that one needs those weapons? Strategists gradually find it difficult to argument; over and over again they claim that an abandonment of nuclear weapons would make the world unsafer. But development has gradually passed over them. Nevertheless, one finds it hard to throw overboard considerations which for years have determined one's thinking. (orig./HSCH) [de

  14. Nuclear non-proliferation: failures and prospects

    International Nuclear Information System (INIS)

    Imai, R.; Press, R.

    1980-01-01

    The objective of this paper is to examine the evolution of combined political and technical attempts to achieve worldwide acceptance of a commitment to non-proliferation, to note failures to date, and to identify essential factors to be satisfied if greater and necessary success is to be achieved in the immediate future. For this it is necessary to separate the realism and unrealism so often involved in discussing the concept of non-proliferation, as defined above, particularly if treated as a moral principle rather than as part of a general security issue reflecting shifts in regional and global stability. The political nature of the non-proliferation problem is underlined by the fact that whereas five nuclear weapon states are currently accepted, any threatened increase in that number is discouraged by every possible peaceful means. This fact combines political acceptance of an existing international situation with a belief that any addition to the present number must lead to international instability. Success in preventing additions may be more readily achieved through political understanding and perhaps some compromises, in particular cases, rather than through seeking a universal solution to a generalized problem

  15. Future technology challenges in non-proliferation

    International Nuclear Information System (INIS)

    Richardson, J.H.

    2004-01-01

    Radiation detection technologies are an important tool in the prevention of proliferation. A variety of new developments have enabled enhanced performance in terms of energy resolution, spatial resolution, predictive modeling and simulation, active interrogation, and ease of operation and deployment in the field. For example, various gamma ray imaging approaches are being explored to combine spatial resolution with background suppression in order to enhance sensitivity at reasonable standoff distances and acquisition times. New materials and approaches are being developed in order to provide adequate energy resolution in field use without the necessity for liquid nitrogen. Finally, different detectors combined into distributed networks offer promise for detection and tracking of radioactive materials. As the world moves into the 21st century, the possibility of greater reliance on nuclear energy will impose additional technical requirements to prevent proliferation. In addition to proliferation resistant reactors, a careful examination of the various possible fuel cycles from cradle to grave will provide additional technical and nonproliferation challenges in the areas of conversion, enrichment, transportation, recycling and waste disposal. Radiation detection technology and information management have a prominent role in any future global regime for nonproliferation beyond the current Advanced Protocol. This work was performed under the auspices of the U.S. Department of Energy by University of California, Lawrence Livermore National Laboratory under contract No. W-7405-Eng-48. (author)

  16. Non proliferation of nuclear weapons?

    International Nuclear Information System (INIS)

    Le Guelte, Georges

    2015-10-01

    After having evoked the behaviour of nuclear countries regarding the development of nuclear weapons and uranium procurement, or nuclear programmes after the Second World War until nowadays, the author presents the non proliferation Treaty (NPT) as a construction at the service of super-powers. He comments and discusses the role of the IAEA control system and its evolutions: a control limited to declared installations, an export control with the spectre of plutonium, a control system thwarted by some technological innovations, information systems coming in, and an additional protocol related to the application of guarantees. He comments the evolution of the context from a bipolar world to a world without pole which raises the issue of how to have commitments respected: description of the role and practice of non proliferation during the Cold War, after the Cold War, and in a world without governance

  17. The fight against weapons of mass destruction at the crossroads; La lutte contre la proliferation des armes de destruction massive a la croisee des chemins

    Energy Technology Data Exchange (ETDEWEB)

    Biad, A. [Rouen Univ., Faculte de Droit, de Sciences Economiques et de Gestion, 76 - Mont-Saint-Aignan (France)

    2004-07-01

    Under the joint pressure of the US unilateralism and of some proliferating countries, the non-proliferation regimes are today at the crossroads. Despite the enormous efforts mobilized so far, the proliferation of weapons of mass destruction appears as inescapable. This article analyzes the reasons of the continuous erosion of non-proliferation regimes and the possible means to delay this phenomenon: counter-proliferation measures, control of exported nuclear technologies and equipments, use of diplomatic and politico-economical means, controlled multilateral disarmament. (J.S.)

  18. Inter-relations between regional and global approaches to nuclear non-proliferation

    International Nuclear Information System (INIS)

    Simpson, J.

    1995-01-01

    It is now becoming evident that the end of the East-West conflict has had a significant effect upon both global and regional security structures. From a situation where regional arrangements were, in the main, determined and driven by pressures arising from the bipolar division which permeated all aspects of the global political system, they increasingly have an independent existence. This has enabled such arrangements to be tailored to local circumstances in a manner which is not possible with global agreements. In particular, it has become apparent that enhanced constraints on peaceful nuclear activities and much more intrusive inspection and monitoring procedures, can more easily be negotiated on a regional basis than a global one. It also appears that nuclear weapon states are prepared to make unconditional commitments about nuclear weapon use on a regional basis, whereas they may not be prepared to do so on a global one. In short, regional approaches enable fine-tuning of the international non-proliferation regime to occur, and for measures to be taken on a regional level that would be politically unacceptable on the global level, due to their discriminatory nature. In the years ahead additional Nuclear-Weapon-Free Zone (NWFZ) agreements may be negotiated, covering more of the land area of the globe. In parallel, regional nuclear cooperation and safeguarding agreements might also be expected to develop along the lines of EURATOM and ABACC. This in turn may move the states which remain outside of the NPT to a similar position to Argentina and Brazil at the moment: to an acceptance that whatever their opposition in principle to the NPT and the system of supplier export guidelines, the commitments they have already accepted on a regional level are more intrusive and constraining than those they would incur if they were to have acceded to the Treaty. In these circumstances, accession to the NPT becomes a distinct possibility, and thus the regional approach to non-proliferation

  19. Perspectives and benefits of the non-proliferating fuel cycle

    International Nuclear Information System (INIS)

    Parker, F.

    2012-01-01

    The world community has faced the issues of nuclear non-proliferation for decades. Frank Parker, Emeritus Distinguished Professor at Vanderbilt University, has proposed a non-proliferating fuel cycle, which greatly reduces the risk of use of nuclear materials for military purpose. A simplified fuel cycle with reduced opportunities for proliferation of nuclear weapons and permanent disposal of radioactive wastes as well as a reference sub-seabed HLW disposal system are described [ru

  20. The new US nuclear non-proliferation and export policy

    International Nuclear Information System (INIS)

    Welck, S. von.

    1981-01-01

    The future American nuclear non-proliferation and export policy will be determined chiefly by three elements: (1) Adherence to the former objective of nuclear non-proliferation. (2) A large and varied assortment of old and new tools for implementing this goal. (3) Much more differentiation in applying these tools in the light of the reliability, with respect to non-proliferation policy, of the respective partner. Consequently, it would make little sense for the new Administration to force upon allied industrialized countries, whose nuclear technologies are at the same level as that of the United States, restrictive rules on reprocessing and breeder technology. The new measures designed to curb proliferation are especially meant to destroy motivations that could cause states to own nuclear explosives. This also applies to the removal of economic motivations. (orig.) [de

  1. Non-proliferation aspects of long term assurance of supply

    International Nuclear Information System (INIS)

    1978-01-01

    The meetings in this section deal with the non-proliferation aspects of long-term assurance of supply of the nuclear fuel cycle. A list of 12 fundamental questions concerning the observation and application of the non-proliferation regulations is followed by the comments made by representatives of 10 countries

  2. The Non-Proliferation Treaty increases security

    International Nuclear Information System (INIS)

    Kahiluoto, K.

    1995-01-01

    Extension of the Nuclear Non-Proliferation Treaty indefinitely was a historic decision. The Treaty is the most extensive international agreement on security policy to date; now its obligations have become a permanent part of international justice. Moreover, the NPT represents a political and moral obligation. Through the NPT, the international community has made a permanent commitment to restrict the proliferation of nuclear weapons. Increasing pressures will be applied to the few countries still outside the NPT, making it more likely that these countries will eventually change their views. The likelihood of regional bans on nuclear weapons in the Middle East and in Asia, too, will increase. The Treaty promotes the establishment of new nuclear-free zones. The nuclear-free zone in Latin America - the countries covered by the Tlatelolco Treaty - is already very close to its full implementation. Finland is firmly committed to the obligations of the Non-Proliferation Treaty. The NPT Conference of 1995 was among the first international meetings in which Finland participated, and took an active role, as a Member State of the European Union. (orig.)

  3. United Nations study on disarmament and non-proliferation education

    International Nuclear Information System (INIS)

    2003-01-01

    Science and technology transformed the world in the twentieth century. Living standards improved but warfare was rendered more deadly. Weapons of mass destruction - biological, chemical and nuclear - and their means of delivery were developed, as ever more sophisticated conventional armaments were produced and disseminated. The horrors and destruction of armed conflict persist. The need for disarmament and non-proliferation education and training has never been greater. Indeed, changing concepts and perceptions of security and threat magnify the urgency for new thinking to pursue disarmament and non-proliferation goals. More than a decade after the end of the cold war and at the start of the twenty- first century, there is a pressing need to combat ignorance, complacency and a culture of violence. These can be countered through long-term programmes of education and training, especially those related to disarmament and non- proliferation of weapons of mass destruction and their means of delivery, with a view to their reduction and complete elimination. At the same time, concern has heightened over the global threat of the excessive and destabilizing proliferation of conventional weapons, especially small arms and light weapons, rendering more acute the need to combat such proliferation in a sustained way through disarmament and non-proliferation education and training. Additionally there is a need to raise awareness of new challenges to international security and the process of disarmament. Among them, terrorism, with the possibility of the use of weapons of mass destruction, is a source of particular concern. Other challenges, such as organized crime, poverty, human rights abuses and environmental concerns must also be taken into account. Education and training remain important but under utilized tools for promoting peace, disarmament and non-proliferation. The present report addresses that issue and proposes ideas for action

  4. Experience in non-proliferation verification: The Treaty of Raratonga

    International Nuclear Information System (INIS)

    Walker, R.A.

    1998-01-01

    The verification provisions of the Treaty of Raratonga are subdivided into two categories: those performed by IAEA and those performed by other entities. A final provision of the Treaty of Raratonga is relevant to IAEA safeguards according to support of the continued effectiveness of the international non-proliferation system based on the Non-proliferation Treaty and the IAEA safeguards system. The non-IAEA verification process is described as well

  5. Non-proliferation and nuclear disarmament

    International Nuclear Information System (INIS)

    Shea, M.

    2000-01-01

    Fissionable materials are common to all nuclear weapons and controls on the production, storage, processing and use of fissionable materials provides one means to address non-proliferation and disarmament. In this article, the relevance of such controls is examined and the current situation and future prospects are assessed. (authors)

  6. On the non-proliferation framework of Japan's peaceful nuclear utilization program

    International Nuclear Information System (INIS)

    Kano, Takashi

    1996-01-01

    The Conference of the States Party to the Treaty on the Non-proliferation of Nuclear Weapons (hereinafter referred to as the NPT) convened in New York, from April 17 to May 12, 1995 and decided that the NPT shall continue in force indefinitely, after reviewing the operation and affirming some aspects of the NPT, while emphasizing the ''Decision on Strengthening the Review Process'' for the NPT and the ''Decision on Principles and Objectives for Nuclear Non-proliferation and Disarmament,'' also adopted by the Conference. In parallel, Japan made its basic non-proliferation policy clear in the ''Long-Term Program for Research, Development and Utilization of Nuclear Energy'' which was decided by the Atomic Energy Commission (chaired by Mikio Oomi, then Minister of the Science and Technology Agency of Japan) in June 1994. The Long-Term Program discusses various problems facing post-Cold-War international society and describes Japan's policy for establishing international confidence concerning non-proliferation. This paper summarizes Japan's non-proliferation policy as articulated in the Long-Term Program, and describes some results of an analysis comparing the Long-Term Program with the resolutions on the international non-proliferation frameworks adopted by the NPT conference

  7. Asia nuclear-test-ban network for nuclear non-proliferation

    International Nuclear Information System (INIS)

    Shinohara, Nobuo; Kokaji, Lisa; Ichimasa, Sukeyuki

    2010-01-01

    In Global Center of Excellence Program of The University of Tokyo, Non- Proliferation Study Committee by the members of nuclear industries, electricity utilities, nuclear energy institutes and universities has initiated on October 2008 from the viewpoints of investigating a package of measures for nuclear non-proliferation and bringing up young people who will support the near-future nuclear energy system. One of the non-proliferation issues in the Committee is the Comprehensive Nuclear-Test-Ban Treaty (CTBT). Objective of this treaty is to cease all nuclear weapon test explosions and all other nuclear explosion. This purpose should be contributed effectively to the political stability of the Asian region by continuous efforts to eliminate the nuclear weapons. In the Committee, by extracting several issues related to the CTBT, conception of 'Asia nuclear-test-ban network for nuclear non-proliferation' has been discussed with the aim of the nuclear-weapon security in Asian region, where environmental nuclear-test monitoring data is mainly treated and utilized. In this paper, the conception of the 'network' is presented in detail. (author)

  8. Information management in NACD regimes: a comparative analysis

    International Nuclear Information System (INIS)

    Unger, R.

    1998-01-01

    While all non-proliferation, arms control and disarmament (NACD) regimes must address the issue of information management, this area has remained an under-explored part of the arms control field. This paper compares information management processes across a variety of NACD regimes for the purpose of identifying potential synergies between regimes and suggesting means by which to strengthen future arms control verification efforts. The paper explores the information management systems of the International Atomic Energy Agency (IAEA), the United Nations Special Commission in Iraq (UNSCOM), the Conventional Forces in Europe Agreement (CFE), and the Comprehensive Test Ban Treaty (CTBT). (author)

  9. Nuclear disarmament. Options for the coming non-proliferation treaty surveillance cycle

    International Nuclear Information System (INIS)

    Mueller, Harald

    2011-01-01

    The report is aimed on the nuclear disarmament discussion with respect to the disagreement of nuclear weapon states and those without nuclear weapons, esp. the non-aligned movement (NAM) concerning the non-proliferation treaty. The report covers the following issues: The role of the non-proliferation treaty, nuclear disarmament in the last surveillance conference 2010, the different disarmament philosophies, the possibilities of bridging the disagreement, further disarmament options for the future non-proliferation treaty surveillance cycle, German options for the future surveillance cycle.

  10. Non-proliferation and international safeguards. [Booklet by IAEA

    Energy Technology Data Exchange (ETDEWEB)

    1978-01-01

    This booklet consists of 13 separate, brief analyses related to the subject title, namely: The International Scope of IAEA Safeguards; Application of Safeguards Procedures; Computer-Based Safeguards Information and Accounting System; IAEA Training Activities Related to State Systems of Nuclear Materials Accountancy and Control; Surveillance and Containment Measures to Support IAEA Safeguards; International Plutonium Management; Safeguards for Reprocessing and Enrichment Plants; Non-Destructive Assay: Instruments and Techniques for Agency Safeguards; The Safeguards Analytical Laboratory: Its Functions and Analytical Facilities; Resolution of the UN General Assembly on the Treaty on the Non-Proliferation of Nuclear Weapons of 12 June 1968; The Treaty on the Non-Proliferation of Nuclear Weapons; Final Declaration of the Review Conference of the Parties to the Treaty on the Non-Proliferation of Nuclear Weapons, May 1975; Resolutions on the IAEA's Work in the Field of the Peaceful Uses of Atomic Energy, adopted by the UN General Assembly on 8 and 12 December, 1977; and a Map on the NPT situation in the world (with explanations).

  11. Approaches to nuclear disarmament and non-proliferation

    International Nuclear Information System (INIS)

    Subrahmanyam, K.

    1981-01-01

    The logic behind the approach of the nuclear weapon states (NWS) to the issue of nuclear disarmament and non-proliferation is based on: (1) The assumption that the less the number of decision makers who could initiate a nuclear war less the probability of war, (2) the claim of the NWS that their nuclear weapons are under strict control, and (3) the claim of the NWS who have signed the Non-Proliferation Treaty (NPT) that the Treaty is being scrupulously observed by them. This logic is critically examined in the light of disclosures that indicate that: (1) both vertical and horizontal proliferation is going on without respite among the NWS, and (2) the fissile material is clandestinely being allowed to be diverted to the favoured clients by one or more of the NWS. These NWS are not subject to any safeguards under the NPT. They are using the NPT and the concept of nuclear free zone as a sort of tactic to divert the attention from the correct approach to the disarmament and to impose their hegemony over the Third World Countries. Moreover, the NPT has conferred a sort of legitimacy to the possession of nuclear weapons by the NWS. In these circumstances their preaching to the Third World countries about nuclear disarmament and non-proliferation sounds hypocritical. The correct approach to these issues would be to put the nuclear weapons under the category of weapons of mass destruction and to ban their use under a non-discriminatory international convention as has been done in the case of biological and chemical weapons. (M.G.B.)

  12. Non-proliferation and international safeguards

    International Nuclear Information System (INIS)

    Blix, H.

    1992-01-01

    Full text: In my view, drastic nuclear disarmament by nuclear weapon States could be coupled with universal commitment to non-proliferation by non-nuclear weapon States by 1995 when the extension of the NPT Will be discussed. The incentives and disincentives for making and stockpiling nuclear weapons are first of all in the political and security fields, (Global and regional detente reduce the incentive, With the cold war gone, the US and Russia are now agreeing on far-reaching cuts in their nuclear arsenals and at some point the other declared nuclear weapon States Will follow.In the regional fields, we have seen how Argentina and Brazil are about to commit themselves to exclusively peaceful uses of the atom through the Latin American Tlatelolco Treaty. And we have seen how South Africa has joined the NPT. A new wave of States adhering to the NPT may be expected from countries in the former Soviet Union. Some have already come, others are on the way. Detente in the Middle East and on the Indian subcontinent would improve the outlook for non-proliferation in these areas. A second barrier to nuclear proliferation lies in export restrictions on sensitive nuclear material and equipment, Following the discoveries in Iraq, these restrictions are being strengthened in a large number of States. A third barrier to nuclear proliferation lies in the economic and political consequences that would follow for a State if IAEA safeguards inspection revealed activities aimed at the production of nuclear weapons. These must have a high degree of reliability. The case of Iraq showed that it was possible for a closed, highly militarized State to hide nuclear activities from the IAEA and the world We are now drawing the lessons from this case. It is not physically possible for inspectors to look into every building and basement in vast countries, They must have information about where to look, and the IAEA is significantly strengthening its information basis. The IAEA has also re

  13. History, framework and perspectives of international policy for preventing the proliferation of nuclear weapons

    International Nuclear Information System (INIS)

    Czakainski, M.

    1985-12-01

    The study analyses the framework conditions, such as the Non-Proliferation Treaty and the international non-proliferation regime and their interlacement with international nuclear energy policies, and evaluates the results achieved so far on an international level by the efforts directed towards preventing the proliferation of nuclear weapons. The conclusion to be drawn as stated by the author is that the classical tool of non-proliferation policy - denial of technology transfer - will lose in importance and give way to enhanced, controlled cooperation between countries of the Third World and the industrialised countries. Another instrument that will maintain its value for non-proliferation policy is cooperation for political stabilisation in those parts of the world where regional conflicts might aggravate. (orig./HP) [de

  14. Report of 'the 2014 international forum on peaceful use of nuclear energy, nuclear non-proliferation and nuclear security. Future direction toward promoting non-proliferation and the ideal method of developing human resources using Centers of Excellence (COEs) following the new strategic energy plan'

    International Nuclear Information System (INIS)

    Yamaga, Chikanobu; Tomikawa, Hirofumi; Kobayashi, Naoki; Naoi, Yosuke; Oda, Tetsuzo; Mochiji, Toshiro

    2015-10-01

    The Japan Atomic Energy Agency (JAEA) held 'International Forum on Peaceful Use of Nuclear Energy, Nuclear Non-proliferation and Nuclear Security – Future direction toward promoting non-proliferation and the ideal method of developing human resources using Centers of Excellence (COEs) following the New Strategic Energy Plan -' on 3 December 2014, with the Japan Institute of International Affairs (JIIA) and School of Engineering, The University of Tokyo, and International Nuclear Research Center, Tokyo Institute of Technology as co-hosts. In the Forum, officials and experts from Japan, the United States explained their efforts regarding peaceful use of nuclear energy, nuclear non-proliferation and nuclear security. Discussion was made in two panels, entitled 'Effective and efficient measures to ensure nuclear non-proliferation based on domestic and foreign issues and the direction and role of technology development' and 'Roles of nuclear security COEs and future expectations'. In Panel Discussion 1, as the nuclear non-proliferation regime is facing various problems and challenges under current international circumstances, how to implement effective and efficient safeguards was discussed. In Panel Discussion 2, panelists discussed the following three points: 1. Current status of Nuclear Security Training and Support Centers and COEs, and Good Practice; 2. What these centers can do to enhance nuclear security (New role for COEs); 3. Regional cooperation in the Nuclear Security Training and Support Center (NSSC) and COEs in states, which the IAEA recommends establishing, and international cooperation and partnerships with international initiatives (New Role). Officials and experts from Japan, IAEA, the United States, France, Republic of Korea, and Indonesia participated in the panel and made contributions to active discussion. This report includes abstracts of keynote speeches, summaries of two panel discussions and materials of the

  15. The future of nuclear non-proliferation in South Asia

    International Nuclear Information System (INIS)

    Siddiqa, A.

    1997-01-01

    Nuclear proliferation in South Asia is currently one of the hot topics in world politics. The concern of the international community, and especially the USA, over this issue is coupled with the fear of nuclear conflict between India and Pakistan. As a result, Washington has been using its 'stick and carrot' policy to persuade the two countries involved not to develop their nuclear programs for military purposes. However both countries have not only continued to develop their nuclear ambitions, but seem to have achieved vertical nuclear proliferation. This paper examines the future non-proliferation in the South Asian region in the 1990s. This will be achieved by looking at the following: the development of the nuclear capabilities of both India and Pakistan; how these programs have been developed; the reasons for acquiring the capability for non-conventional defence; the real fear in terms of nuclear proliferation in the region; the possible options for dealing with nuclear proliferation in South Asia

  16. International Cooperation for Enhancing Nuclear Safety, Security, Safeguards and Non-proliferation : 60 Years of IAEA and EURATOM

    CERN Document Server

    Abousahl, Said; Plastino, Wolfango

    2018-01-01

    This open access book examines key aspects of international cooperation to enhance nuclear safety, security, safeguards, and non-proliferation, thereby assisting in development and maintenance of the verification regime and fostering progress toward a nuclear weapon-free world. The book opens by addressing important political, institutional, and legal dimensions. Current challenges are discussed and attempts made to identify possible solutions and future improvements. Subsequent sections consider scientific developments that have the potential to increase the effectiveness of implementation of international regimes, particularly in critical areas, technology foresight, and the ongoing evaluation of current capabilities. The closing sections examine scientific and technical challenges and discuss the role of international cooperation and actions of the scientific community in leading the world toward peace and security. The book – which celebrates 60 years of IAEA Atoms for Peace and Development and the EURA...

  17. URENCO: A Multinational Contribution to Non-Proliferation

    International Nuclear Information System (INIS)

    Korbmacher, T.

    2015-01-01

    URENCO was founded in 1970 following the signing of the Treaty of Almelo by the governments of Germany, the Netherlands and the UK. The fundamental principles for effective supervision of URENCO's technology and enrichment operations with respect to non-proliferation issues have been laid down in this treaty. In order to enable the construction of a URENCO enrichment facility in the USA and to permit the transfer of classified information into the USA, another treaty has been concluded in 1992. The US government entered into the Treaty of Washington together with the governments of Germany, the Netherlands and the UK to ensure that the same conditions that had been agreed in the Treaty of Almelo would also apply to the US. To allow for the completion of the joint venture with Areva regarding the URENCO Group's technology business ETC, the Treaty of Cardiff has been signed on 12 July 2005 by the governments of Germany, the Netherlands, the UK and France. Through this treaty, France is obliged to adhere to the principles of the Treaty of Almelo. For each treaty, control bodies have been formed with representatives of the governments of the signatory countries. These committees exercise the role of effective supervision of the technology and operations with respect to non-proliferation issues. They also consider all questions concerning the safeguards system (as established by IAEA/Euratom), classification arrangements and security procedures, exports of the technology and enriched uranium, as well as other non-proliferation issues. The presentation describes how the multinational structure of URENCO contributes to Non-Proliferation on the basis of the above mentioned treaties. Beyond that, the international cross linking of operational working groups and committees within the URENCO Group structure is explained. This structure implies an additional assurance to achieve the safeguards goals set. (author)

  18. The IAEA and non-proliferation: is quiescence progress

    International Nuclear Information System (INIS)

    Herron, L.W.

    1983-01-01

    The purpose of this paper is to evaluate the current status of more important non-proliferation aspects affecting or involving the IAEA. The questions dealt with cover in particular the Non-Proliferation Treaty, the Tlatelolco Treaty, the Committee on Assurances of Supply established by the IAEA in 1980 and the International Plutonium Storage Study prepared by an IAEA expert group. The author concludes that in a number of areas involving this Agency, recent considerable activity at both political and technical levels has produced few tangible results althrough the situation is not static. (NEA) [fr

  19. Swedish support programme on nuclear non-proliferation in Central and Eastern Europe and Central Asia

    Energy Technology Data Exchange (ETDEWEB)

    Ek, P.; Andersson, Sarmite [Swedish Nuclear Power Inspectorate, Stockholm (Sweden); Wredberg, L. [ILG Consultant Ltd., Vienna (Austria)

    2000-06-15

    convinced understanding and opinion of the Swedish Support Programme Management that the States in question are seriously motivated and are carrying out an ambitious work to develop and improve their national non-proliferation regimes, in spite of their shortcomings concerning financial and human resources. For those States, with which Sweden has established support and co-operation programmes with 'full-scope' non-proliferation objectives, it is judged that the goals reached, up till now, are very satisfactory, and that the States in question have come a long way towards the fulfilment of international requirements. The Programme is now entering a third phase and the future Programme plans are currently under consideration. A broad outlook of the future activities is made in chapter D of this report.

  20. Swedish support programme on nuclear non-proliferation in Central and Eastern Europe and Central Asia

    International Nuclear Information System (INIS)

    Ek, P.; Andersson, Sarmite; Wredberg, L.

    2000-06-01

    convinced understanding and opinion of the Swedish Support Programme Management that the States in question are seriously motivated and are carrying out an ambitious work to develop and improve their national non-proliferation regimes, in spite of their shortcomings concerning financial and human resources. For those States, with which Sweden has established support and co-operation programmes with 'full-scope' non-proliferation objectives, it is judged that the goals reached, up till now, are very satisfactory, and that the States in question have come a long way towards the fulfilment of international requirements. The Programme is now entering a third phase and the future Programme plans are currently under consideration. A broad outlook of the future activities is made in chapter D of this report

  1. Does interdependence alleviate proliferation risks in Asia?

    International Nuclear Information System (INIS)

    Yoshida, Osamu

    1997-01-01

    As the extension Conference of the Non-Proliferation Treaty ended with its unlimited extension without any modification of the treaty obligation of the nuclear-weapon states to nuclear disarmament, the prospect of the regime to incorporate those suspected nuclear powers in Asia, namely India, Pakistan and Israel, has become dark. In this paper the problem of proliferation risk centred in India is analysed. It is well known that India was the first to criticize the Non-Proliferation Treaty regime as highly discriminating between the five nuclear haves and the rest. As was always the case, India's point is logically persuasive and consistent. However, it is also true that the logical or legal point of view does not always solve the problem. Therefore, we look at the regional and international political constellation in which any assertion has to be constructed. At present there is very little possibility that this region will become nuclear-free. This is because the horizontal proliferation, that has seemingly taken place here, is the result of a 'nuclear chain reaction', starting with a minor nuclear-weapon state, China. However, the economic upsurge in the region now throws the nuclear chain-reactions into the background. It has come to a standstill and the future of nuclear proliferation here will have to be decided by global nuclear disarmament, as there is no motivation on the side of the two Asian giants to agree on the reduction in their nuclear arsenals, though under American pressure, another suspected nuclear power, Pakistan, may have to give up its nuclear development plan

  2. Role of non-governmental organizations in formation of non-proliferation culture in new independent countries (NIC)

    International Nuclear Information System (INIS)

    Sevchik, M.

    2000-01-01

    Purpose of the report is demonstrate the non-governmental organizations (NGO) role in formation of non-proliferation culture in former Soviet Union. Activity of Center of Non-proliferation Problems Investigation (CNPI) of Monterey Institute of International Investigations and its collaboration with existing in Commonwealth of Independent States (CIS) non-governmental organizations is considered as example. Brief information about CNPI and reasons for it representatives opening of in Kazakhstan and in other CIS-countries, as well as cooperation of NGO in Belarus, Kazakhstan, Russia and Ukraine for creation on Central Asia zone free from nuclear weapon ia given. Some measures which could promote to formation of non-proliferation culture in region are suggested

  3. Staying ahead of the game [The world's nuclear regime is being tested like never before

    International Nuclear Information System (INIS)

    Heinonen, O.J.

    2007-01-01

    The nuclear non-proliferation regime today faces a number of challenges. Not all would agree that the system is 'in crisis', but we can confidently say that the regime is certainly being tested. It goes without saying that the reported nuclear test by DPRK in October 2006 has not made the situation easier. So we should begin to find innovative solutions to overcome vulnerabilities or the international nuclear safeguards regime will become obsolete. The Treaty on the Non-Proliferation of Nuclear Weapons (NPT) was ratified more than 30 years ago. Since then the world has undergone rapid social, political and economic changes, which have resulted in a changed non-proliferation landscape. Developments in the three pillars of the NPT -disarmament, technology transfer and verification- have not necessarily been even. The IAEA has a role to play, in particular, in the latter two pillars. Although one might argue that there has been slow progress with regards to disarmament, it is my belief that we should continue to improve nuclear verification methods and techniques to keep up with the changing non-proliferation landscape. If we fail to do so, we might not only impact international safeguards, but also the future prospects of peaceful nuclear applications. During the last two decades we have seen three major developments related to nuclear non-proliferation: the increased dissemination of nuclear technology and nuclear know-how, particularly in light of renewed interest in nuclear power; a renewed drive on the part of a few States to acquire technology suitable for nuclear weapons purpose; the emergence of clandestine procurement networks. Under the NPT regime, there is nothing illegal about any State having enrichment or reprocessing technology. However, we ought to ensure that nuclear material and infrastructure is not used for illicit and non-peaceful purposes. Better control of access to nuclear fuel cycle technology is being explored through initiatives such as

  4. Proliferation Control Regimes: Background and Status

    National Research Council Canada - National Science Library

    Nikitin, Mary B; Kerr, Paul; Bowman, Steve; Hildreth, Steven A

    2008-01-01

    .... national security interests. Multilateral regimes were established to restrict trade in nuclear, chemical, and biological weapons and missile technologies, and to monitor their civil applications...

  5. Proliferation Control Regimes: Background and Status

    National Research Council Canada - National Science Library

    Squassoni, Sharon; Bowman, Steve; Hildreth, Steven A

    2006-01-01

    .... national security interests. Multilateral regimes were established to restrict trade in nuclear, chemical, and biological weapons and missile technologies, and to monitor their civil applications...

  6. Canada and international safeguards. Verifying nuclear non-proliferation. Verification brochure no. 5

    Energy Technology Data Exchange (ETDEWEB)

    1990-01-01

    The Non-Proliferation Treaty (NPT) came into force in 1970 and now has about 140 signatory nations. By creating legal barriers against proliferation and by promoting an international non-proliferation ethic, the NPT has promoted international peace and security. A key ingredient has been the confidence generated through verification by IAEA safeguards. By the end of 1988 IAEA safeguards agreements had been concluded with about 100 countries, including Canada. Over 500 nuclear facilities worldwide are under safeguards or contain safeguarded nuclear material. The existence of this credible and effective safeguards system makes international trade in nuclear equipment and materials possible, monitoring the transfer of nuclear technology to developing countries as well as between industrial countries. Canada is committed to non-proliferation and IAEA safeguards. Canadian non-proliferation policy is among the strictest in the world, even though opportunities have been lost to sell Canadian technology abroad as a result.

  7. The international nuclear non-proliferation system: Challenges and choices

    International Nuclear Information System (INIS)

    Simpson, J.; McGrew, A.G.

    1984-01-01

    When a topic has been under discussion for almost 40 years there is a danger that the literature will become excessively esoteric and that, as Philip Grummett suggests, '...a new scholasticism will arise' (p.79). Originating in a November l982 seminar co-sponsored by the British International Studies Association and the Foreign and Commonwealth Office, this volume is a refreshing, well conceived, and well written antidote to that trend. It is also well timed for the 1985 NPT Review Conference. The eight chapters of the volume are divided into three sections. Following an introduction by Anthony McGrew that touches on all the major themes of the volume, the first section deals with the existing non-proliferation system. In three chapters the historical, institutional and policy-making elements of the present system are outlined. There is a vignette on the Nuclear Suppliers Group in Wilmshurst's chapter one (pp. 28-33). Fischer's informative chapter on the IAEA is followed by Gummett's examination of policy options, including, for example, the linking of conventional weapons transfer to non-proliferation policies. The second section, also of three chapters, examines current issues: the state of the international nuclear industry, and the non-proliferation policies of the United States and Britain. Walker's chapter focuses chiefly on change in the industry-from monopoly to pluralism in suppliers, the effect of the economic recession, and the combined effect of these two factors on international politics. Devine's American non-proliferation chapter is a statement of the State Department view, whilst Keohane's chapter on Britain attempts to put the Trident procurement into a proliferation context. The British chapter is present because of ethnocentric considerations

  8. Between Shadow and Light: The Treaty on the Non-Proliferation of Nuclear Weapons Forty Years On

    International Nuclear Information System (INIS)

    Abdelwahab, Biad

    2010-01-01

    context marked by conflicting signs in terms of non-proliferation and disarmament, e.g. a new American administration more open to multilateralism and proliferation crises (A). The nuclear non-proliferation regime of which the NPT is the touchstone is based on a complex balance between the right to use nuclear energy for peaceful purposes, non-proliferation control requirements and commitment to disarmament. However, major challenges are weakening that balance underpinning the 'global nuclear order'

  9. TOWARDS FULFILLMENT OF FUNDAMENTAL RULES OF HUMANITARIAN LAW IN THE CONTEXT OF THE NUCLEAR NON-PROLIFERATION TREATY

    Directory of Open Access Journals (Sweden)

    s. Bagheri

    2016-01-01

    Full Text Available The Non-Proliferation Treaty (NPT is an international treaty that should be implemented during both peace and wartime. However, the obligations included in the treaty are dependent upon states' attitudes regarding other issues. Non-use of nuclear weapons is directly related to negotiations done for the purpose of non-proliferation of nuclear weapons, non-production or accumulation by other means and disarmament. In our day, prevention of the proliferation of nuclear weapons has been one of the issues of international law.The present study is of crucial significance due to its endeavor to clarify the general principles of Humanitarian Law in a relationship to the threat of nuclear weapons' up to now, a special norm; significantly limiting or completely prohibiting the use of nuclear weapons, has not been accepted in international law. However, customary international humanitarian law regarding the use of nuclear weapons holds great value because of its purpose in eliminating nuclear weapons as a means of war through ascertaining their non-use and also appeasing the importance of nuclear ascendancy. In this respect, the NPT regime and its relationship with international humanitarian law will be discussed. Firstly, the NPT background, formation, main objectives and principles will be analyzed. In order to evaluate the relationship between the NPT and humanitarian law, the humanitarian obligations in general, humanitarian obligations in the context of the NPT and fulfillmen t of these obligations under the NPT should be studied. One of the main parts of the study is nuclear disarmament obligation included in the NPT. In this section, nuclear disarmament obligation in the context of the NPT and the legal framework of possible, general and comprehensive disarmament will be examined.

  10. Promotion of Nuclear Non-proliferation in East Asia

    International Nuclear Information System (INIS)

    Hwang, Yong Soo

    2009-07-01

    KAERI has jointly worked with Sandia National Laboratories for Nuclear Energy Non-proliferation in East Asia for the last five years. This project aims at support activities in this joint project between two states. The annual meetings were held during the project period, the 4th one in 2008 and the 5th one in 2009. In addition code comparison between KAERI and SNL's codes for assessing the back-end fuel cycle options was carried out. This project strongly enhances the close tie for the non-proliferation, transparency and safeguards among Korea Japan China Taiwan the United States Russia Malaysia Singapore Indonesia Thailand Vietnam and others for the project period

  11. Previewing the 2010 Nuclear Non-Proliferation Treaty Review Conference

    International Nuclear Information System (INIS)

    Pomper, Miles A.

    2010-01-01

    Despite groundbreaking disarmament pledges and substantial effort, the Obama administration's hopes for a successful Nuclear Non-Proliferation Treaty (NPT) Review Conference may not be fully realised. Many developing countries are in no mood to grant new non-proliferation concessions, such as tightened rules on access to sensitive nuclear technologies, tougher inspection rules, or limits on withdrawing from the treaty. The non-nuclear weapon states (NNWS) remain angered by the failure to move forward on many disarmament commitments pledged at the 1995 and 2000 Conferences. Moreover, progress on disarmament measures under Obama has been slower than hoped, as he faces considerable scepticism in Washington about his strategy. (author)

  12. The international nuclear non-proliferation system: Challenges and choices

    Energy Technology Data Exchange (ETDEWEB)

    Simpson, J.; McGrew, A.G.

    1984-01-01

    When a topic has been under discussion for almost 40 years there is a danger that the literature will become excessively esoteric and that, as Philip Grummett suggests, '...a new scholasticism will arise' (p.79). Originating in a November l982 seminar co-sponsored by the British International Studies Association and the Foreign and Commonwealth Office, this volume is a refreshing, well conceived, and well written antidote to that trend. It is also well timed for the 1985 NPT Review Conference. The eight chapters of the volume are divided into three sections. Following an introduction by Anthony McGrew that touches on all the major themes of the volume, the first section deals with the existing non-proliferation system. In three chapters the historical, institutional and policy-making elements of the present system are outlined. There is a vignette on the Nuclear Suppliers Group in Wilmshurst's chapter one (pp. 28-33). Fischer's informative chapter on the IAEA is followed by Gummett's examination of policy options, including, for example, the linking of conventional weapons transfer to non-proliferation policies. The second section, also of three chapters, examines current issues: the state of the international nuclear industry, and the non-proliferation policies of the United States and Britain. Walker's chapter focuses chiefly on change in the industry-from monopoly to pluralism in suppliers, the effect of the economic recession, and the combined effect of these two factors on international politics. Devine's American non-proliferation chapter is a statement of the State Department view, whilst Keohane's chapter on Britain attempts to put the Trident procurement into a proliferation context. The British chapter is present because of ethnocentric considerations.

  13. The Nuclear Non-Proliferation Treaty: Regulating Nuclear Weapons around the World

    Science.gov (United States)

    Middleton, Tiffany Willey

    2010-01-01

    In May 2010, scientists, national security experts, and state delegates from nations around the world will convene in New York for the 2010 Nuclear Non-Proliferation Treaty Review Conference. They will review current guidelines for nuclear testing and possession of nuclear weapons in accordance with the Nuclear Non-Proliferation Treaty of 1968,…

  14. Non Proliferation of Nuclear

    International Nuclear Information System (INIS)

    Bambang S Irawan

    2004-01-01

    Non-Proliferation Treaty of Nuclear Weapons is the international community's efforts to maintain the security of the world, in order to prevent the spread of nuclear technology and the use of nuclear weapons, promoting cooperation for the use of nuclear peaceful purposes, build mutual trust (Confidence Building Measures) as well as to achieve the ultimate goal of disarmament overall (General and Complete Disarmament). Addressing the post-WTC tragedy, 11 September 2001, the Indonesian government should set up a National Measures (National Action Plan), among others formed the National Security Council and NBC Counter Proliferation Unit, or the National Authority for Nuclear Treaty, preparing national legislation, to prevent the abuse nuclear materials for terrorist acts, prevent Illicit Trafficking of Nuclear materials, developed a National Preparedness and Emergency Response Management in the event of a nuclear accident or attack by the use of nuclear terrorism. Importance of a National Action Plan meant the existence of a national commitment in the context of compliance with treaties and conventions which have been ratified relating to safety, security, safeguards towards a general and complete disarmament, to safeguard national security and maintain peace (safeguards) international

  15. EMP at the Non-Proliferation Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Bell, J. [AWE, Aldermaston (United Kingdom)

    1994-12-31

    This experiment presented an opportunity to field customized equipment designed to detect and record electromagnetic pulse (EMP) emanations from an explosion over a wide frequency range. Any data recorded could be used in conjunction with the seismic methods to further non-proliferation studies. No EMP emanations were detectable from the four sensors deployed outside the tunnel confines.

  16. First annual report on nuclear non-proliferation: supplement to annual report to Congress

    International Nuclear Information System (INIS)

    1979-01-01

    Section 602 of the Nuclear Non-Proliferation Act of 1978 (NNPA) requires that DOE's Annual Report include views and recommendations regarding non-proliferation policies and actions for which the Department is responsible. The Act also requires a detailed analysis of the proliferation implications of advanced enrichment and reprocessing techniques, advanced reactors, and alternative fuel cycles, including an unclassified summary and a comprehensive version containing relevant classified information. The goals of United States non-proliferation policy are to minimize the spread of nuclear weapons and to create a stable international environment for the peaceful use of nuclear energy

  17. Infrasonic measurements of the Non-Proliferation Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Whitaker, R.W.; Noel, S.; Meadows, W. [Los Alamos National Laboratory, NM (United States)

    1994-12-31

    Two infrasonic arrays were operated for the Non-Proliferation Experiment (NPE). The arrays were located at the Nevada Test Site and at St. George, UT. The results were consistent with experience on underground tests, and therefore close to underground nuclear tests of similar size.

  18. Which future for nuclear counter-proliferation?; Quel avenir pour la contre-proliferation nucleaire?

    Energy Technology Data Exchange (ETDEWEB)

    Duval, M.

    2010-07-15

    Dealing with the case of nuclear weapons possessed by nuclear states (but not eventually by terrorists), the author first identifies the constants of counter-proliferation: it is linked to interest conflicts between those who try to preserve their monopoly and those who try to acquire a new weapon either because of a threat or for reasons of regional prestige, the evolution from use to deterrence, the appearance of new actors after the USA and Russia, the role of nuclear tactical weapons, and the future of Russian weapons and know-how. He presents the international counter-proliferation context: the Non Proliferation Treaty (NPT), the IAEA and its controls, the Nuclear Supplier Group (NSG), the nuclear-free zones, the Comprehensive Test Ban Treaty (CTBT), the Missile Technology Control Regime (MTCR). He describes how and why proliferation occurs: uranium enrichment and plutonium technology, political reasons in different parts of the world. Then, he gives an overview of the proliferation status by commenting the cases of Israel, Iraq, India, Pakistan, North Korea, and Iran. He discusses the future of proliferation (involved countries, existence of a nuclear black market) and of counter-proliferation as far as Middle-East and North Korea are concerned. He tries finally to anticipate the consequences for nuclear deterrence strategy, and more particularly for Europe and France

  19. An approach to the successful design of a minicomputer system for nuclear materials management

    International Nuclear Information System (INIS)

    Paul, R.N.; Anderson, L.L.

    1978-08-01

    A development laboratory to study nuclear fuel fabrication techniques is in operation at the Chalk River Nuclear Laboratories (CRNL). To assist operators in the management of nuclear materials in this laboratory, a minicomputer system (INMACS) has been designed and installed. INMACS is implemented on a PDP-11 with a RSTS/E operating system. A data base management package with on-line backup capability has been developed for this application. Fifteen man-years of effort have been spent on designing and building the system. This paper will discuss the philosophy and the design approach followed for the implementation of INMACS. Clear problem definition and careful system design, effective liaison with the users, detailed program specifications, proper co-ordination of the software development effort, and thorough testing of the integrated system, have all contributed to the achievement of the design goals. INMACS has been readily accepted by the users who were previously not conversant with computers. After eight months of operation, no program changes have been necessary and the system has been performing successfully as specified. (author)

  20. Spray characteristics and spray cooling heat transfer in the non-boiling regime

    International Nuclear Information System (INIS)

    Cheng, Wen-Long; Han, Feng-Yun; Liu, Qi-Nie; Fan, Han-Lin

    2011-01-01

    Spray cooling is an effective method for dissipating high heat fluxes in the field of electronics thermal control. In this study, experiments were performed with distilled water as a test liquid to study the spray cooling heat transfer in non-boiling regime. A Phase Doppler Anemometry (PDA) was used to study the spray characteristics. The effects of spray flow rate, spray height, and inlet temperature on spray cooling heat transfer were investigated. It was found that the parameters affect heat transfer of spray cooling in non-boiling regime by the spray characteristics and working fluid thermophysical properties. Then the corresponding droplet axial velocity and Sauter mean diameter (SMD) were successfully correlated with mean absolute error of 15%, which were based upon the orifice diameter, the Weber and Reynolds numbers of the orifice flow prior to liquid breakup, dimensionless spray height and spray cross-section radius. The heat transfer in non-boiling regime was correlated with a mean absolute error of 7%, which was mainly associated with the working fluid thermophysical properties, the Weber and Reynolds numbers hitting the heating surface, dimensionless heating surface temperature and diameter. -- Highlights: → The spray flow rate, spray height, and inlet temperature affect heat transfer of spray cooling in non-boiling regime by the spray characteristics and the working fluid thermophysical properties. → Then the corresponding droplet axial velocity and Sauer mean diameter (SMD) were successfully correlated with mean absolute error of 15%. → The heat transfer in non-boiling regime was correlated with a mean absolute error of 7%.

  1. Reforming the non-proliferation system in the 1980s

    International Nuclear Information System (INIS)

    Wilmshurst, M.J.

    1984-01-01

    The non-proliferation policies of the 1970s were based largely on the misconception that the main danger lay in the possible misuse of civil nuclear-power plants for the production of weapon materials. In consequence their aim, whether by means of denial or control, was to ensure that such misuse was made more difficult in all countries with nuclear-power industries. Less attention was paid to the potential for misuse of the nuclear-research plants in the handful of countries outside the non-proliferation system. The resulting difficulties placed in the way of countries developing their nuclear-power industries damaged relations between the supplier and the consumer states, and discredited any new efforts aimed at strengthening the non-proliferation system. By contrast, the 1980s began, first in INFCE and then in the Committee on Assurances of Supply, with a concerted attempt to re-establish a dialogue based on a relationship of trust between the supplier and the customer states. But a restored consensus will not, on its own, deal with the problem of those states that are outside the non-proliferation system and that have the capability to produce nuclear weapons. The outcome of the work of the Committee on Assurances of Supply may help to attract some of those states into the system, but more needs to be done either by adapting the NPT, making adherence to it appear more attractive, or by devising some alternative code of behaviour for states not party to the Treaty and by seeking to remove the political obstacles that lie in the way of at least some of the potential weapon states adhering to the Treaty

  2. Non-proliferation efforts in South Asia

    International Nuclear Information System (INIS)

    Chellaney, B.

    1994-01-01

    Southern Asia is one of the most volatile regions in the world because of inter-State and intra-State conflicts. Security in the region highly depends on the rival capabilities of the involved states, Pakistan, India, China. Increased Confidence building and nuclear transparency are becoming more significant issues in attaining stability in the region, although non-proliferation efforts in this region have attained little headway

  3. The Rarotonga treaty: regional approach to non-proliferation in the South Pacific

    International Nuclear Information System (INIS)

    Papadimitropulos, P.

    1988-01-01

    The regional approach to the problem of non-proliferation in the South-Pacific-the Rarotonga treaty - is discussed. The regional approach to the problem of non-proliferation is aimed in a wide sense at the assistance to detante in a certain region and the propagation of measures strengthening confidence there. On December 11, 1975 at the initiative of New Zealand and Fiji the UN General Assembly adopted a resolution on the nuclear-free zone in the South-Pacific. In compliance with the Rarotonga treaty a large nuclear-free zone is created. The participants of the Rarotonga Treaty assess the values of the Non-Proliferation Treaty

  4. Long-term proliferation and safeguards issues in future technologies

    International Nuclear Information System (INIS)

    Keisch, B.; Auerbach, C.; Fainberg, A.; Fiarman, S.; Fishbone, L.G.; Higinbotham, W.A.; Lemley, J.R.; O'Brien, J.

    1986-02-01

    The purpose of the task was to assess the effect of potential new technologies, nuclear and non-nuclear, on safeguards needs and non-proliferation policies, and to explore possible solutions to some of the problems envisaged. Eight subdivisions were considered: New Enrichment Technologies; Non-Aqueous Reprocessing Technologies; Fusion; Accelerator-Driven Reactor Systems; New Reactor Types; Heavy Water and Deuterium; Long-Term Storage of Spent Fuel; and Other Future Technologies (Non-Nuclear). For each of these subdivisions, a careful review of the current world-wide effort in the field provided a means of subjectively estimating the viability and qualitative probability of fruition of promising technologies. Technologies for which safeguards and non-proliferation requirements have been thoroughly considered by others were not restudied here (e.g., the Fast Breeder Reactor). The time scale considered was 5 to 40 years for possible initial demonstration although, in some cases, a somewhat optimistic viewpoint was embraced. Conventional nuclear-material safeguards are only part of the overall non-proliferation regime. Other aspects are international agreements, export controls on sensitive technologies, classification of information, intelligence gathering, and diplomatic initiatives. The focus here is on safeguards, export controls, and classification

  5. Long-term proliferation and safeguards issues in future technologies

    Energy Technology Data Exchange (ETDEWEB)

    Keisch, B.; Auerbach, C.; Fainberg, A.; Fiarman, S.; Fishbone, L.G.; Higinbotham, W.A.; Lemley, J.R.; O' Brien, J.

    1986-02-01

    The purpose of the task was to assess the effect of potential new technologies, nuclear and non-nuclear, on safeguards needs and non-proliferation policies, and to explore possible solutions to some of the problems envisaged. Eight subdivisions were considered: New Enrichment Technologies; Non-Aqueous Reprocessing Technologies; Fusion; Accelerator-Driven Reactor Systems; New Reactor Types; Heavy Water and Deuterium; Long-Term Storage of Spent Fuel; and Other Future Technologies (Non-Nuclear). For each of these subdivisions, a careful review of the current world-wide effort in the field provided a means of subjectively estimating the viability and qualitative probability of fruition of promising technologies. Technologies for which safeguards and non-proliferation requirements have been thoroughly considered by others were not restudied here (e.g., the Fast Breeder Reactor). The time scale considered was 5 to 40 years for possible initial demonstration although, in some cases, a somewhat optimistic viewpoint was embraced. Conventional nuclear-material safeguards are only part of the overall non-proliferation regime. Other aspects are international agreements, export controls on sensitive technologies, classification of information, intelligence gathering, and diplomatic initiatives. The focus here is on safeguards, export controls, and classification.

  6. Remarks on nuclear non-proliferation and nuclear disarmament, United Nations Security Council, 24 September 2009, New York, USA

    International Nuclear Information System (INIS)

    ElBaradei, M.

    2009-01-01

    IAEA Director General Dr. Mohamed ElBaradei, Director General of the International Atomic Energy Agency (IAEA) limited his speech to a few key issues. First he stated that the global nuclear non-proliferation regime is fragile and has many shortcomings because the IAEA's legal authority is severely limited in some countries and the IAEA verification mandate is centred on nuclear material and not on weaponization activities. Secondly there is a growing number of states that have mastered uranium enrichment or plutonium reprocessing. Any one of these states could develop nuclear weapons in a short span of time, if, for example, it decided to withdraw from the NPT. There is a need to move from national to multinational control of the nuclear fuel cycle. Thirdly the highest level of protection for nuclear and radioactive material has to be provided. A fourth issue is the need to strengthen the IAEA. A fifth issue is that the IAEA cannot do its work in isolation but depends on a supportive political process, with the Security Council at its core. A sixth issue is that the Security Council must put more emphasis on addressing the insecurities that lie behind many cases of proliferation, such as endemic conflicts, security imbalances and lack of trust. Finally, Dr. Mohamed ElBaradei is gratified to see nuclear disarmament back at the top of the international agenda, as well as recognition of the intrinsic link between nuclear disarmament and non-proliferation

  7. Emerging Trends in Development of International Information Security Regime

    Directory of Open Access Journals (Sweden)

    Elena S. Zinovieva

    2016-01-01

    Full Text Available The article discusses the key trends shaping the international regime on information security. International cooperation in this area at the global level encounters contradictions of state interest. The main actors of the information security are the United States, Russia, China and the EU countries (Britain, France and Germany. The main contradiction is developing between the US on one side and Russia and China on the other. EU countries occupy the middle position, gravitating to that of US. The article proves that international cooperation on information security will reflect the overall logic of the development of international cooperation, which is characterized by a new model of cooperation, with the participation of state and non-state actors, known as multi-stakeholder partnerships and multi-level cooperation. The logic of the formation of an international regime on information security is closest to the logic of the formation of the international non-proliferation regime. It is in the interest of Russia to support the trend towards regionalization of information security regime. Russia can form a regional information security regime in the former Soviet Union on the basis of the CSTO and SCO and potentially on a wider Eurasian space. Such regional regime would give Russia an opportunity to shape the international regime and closely monitor emerging information security issues in the former Soviet Union, and remove the potential threat of "color revolutions".

  8. The nuclear non-proliferation international system before the TNP revision conference (1995)

    International Nuclear Information System (INIS)

    Biad, A.

    1996-01-01

    This document described the international cooperation on nuclear non-proliferation. It consists of different agreements which aim at a pacific use of nuclear energy. However it is shown that many difficulties occurred during the non-proliferation treaty. Questions on equilibrium between control and cooperation, on the link between nuclear weapons reduction and countries equipped with the weapon, on the security for non-equipped countries are separately discussed. (TEC)

  9. Treaty on the non-proliferation of nuclear weapons. 2005 review conference of the Treaty on the Non-Proliferation of Nuclear Weapons, 2 May 2005, United Nations, New York, USA

    International Nuclear Information System (INIS)

    ElBaradei, M.

    2005-01-01

    The core of the Treaty on the Non-Proliferation of Nuclear Weapons can be summed up in two words: 'Security' and 'Development'. While the States Party to this Treaty hold differing priorities and views, I trust that all share these two goals: development for all through advanced technology; and security for all by reducing - and ultimately eliminating - the nuclear threat. These shared goals were the foundation on which the international community, in 1970, built this landmark Treaty. They agreed to work towards a world free of nuclear weapons. They agreed, while working towards this goal, to prevent the acquisition of nuclear weapons by additional States. And they agreed to make the peaceful applications of nuclear energy available to all. Folded together, these agreements, these commitments, are mutually reinforcing. They are as valid today as when they were first made - and even more urgent. What should be all too evident is that, if we cannot work together, each acknowledging the development priorities and security concerns of the other, then the result of this Conference will be inaction. In five years, since the 2000 NPT Review Conference the world has changed. Our fears of a deadly nuclear detonation, whatever the cause, have been reawakened. These realities have heightened the awareness of vulnerabilities in the NPT regime. The Treaty has served us well for 35 years. But unless we regard it as part of a living, dynamic regime - capable of evolving to match changing realities, it will fade into irrelevance and leave us vulnerable and unprotected. The expectations from this Conference are to: re-affirm the goals established in 1970; strengthen the IAEA's verification authority; control over proliferation sensitive parts of the nuclear fuel cycle (activities that involve uranium enrichment and plutonium separation); secure and control nuclear material; show the world that our commitment to nuclear disarmament is firm; back the verification efforts by an

  10. Non-proliferation and nuclear cooperation - accomplishments and challenges

    International Nuclear Information System (INIS)

    Marshall, H.R. Jr.

    1983-01-01

    The purpose of this paper is to assess the accomplishments in non-proliferation and nuclear co-operation since the beginning of President Reagan's administration, and the challenges remaining to be met in those fields. (NEA) [fr

  11. The Non-Proliferation Treaty: Fifteen years after entry into force

    International Nuclear Information System (INIS)

    1985-01-01

    The need to halt a wider spread of nuclear weapons grew out of the realization that the increase in the number of countries possessing such weapons would increase the threat to world security. As the Treaty on the Non-Proliferation of Nuclear Weapons clearly states in its preamble, the proliferation of nuclear weapons would seriously enhance the danger of nuclear war. The Treaty - also known as the non-proliferation Treaty - was concluded in 1968, at a time when there were already five nuclear-weapon Powers: the United States, the Soviet Union, the United Kingdom, France and China. This fact sheet is intended to provide background material on the Treaty, including the events that led to its conclusion, an overview of its provisions and the developments at the two previously held Review Conferences

  12. INFCE and US non-proliferation policy

    Energy Technology Data Exchange (ETDEWEB)

    Donnelly, W H [Library of Congress, Washington, DC (USA)

    1980-12-01

    The International Fuel Cycle Evaluation (INFCE), which published its final reports in February 1980 produced a massive international effort of a kind never before seen. Over a period of two years its eight working groups held 61 meetings involving 519 experts from 46 countries and five international organizations. This article outlines the background and structure of INFCE and discusses how its recommendations diverge from US non-proliferation policy.

  13. Nuclear power and the non-proliferation issue

    International Nuclear Information System (INIS)

    1978-12-01

    This leaflet, issued by the British Nuclear Forum on behalf of the industry, seeks first to place the problem of reconciling the need for nuclear power with its possible weapon uses in a historical perspective. Secondly, it describes the technical and political measures which are now taken, and others which could be introduced in order to ensure that nuclear power, which offers the cheapest and safest large-scale energy source for the future, can be made available without contributing to the proliferation of nuclear weapons. Headings are: introduction; the early years; the IAEA; uranium enrichment; plutonium; secrecy has failed; the Non-Proliferation Treaty; the London Suppliers Group; the situation today; the British position; conclusions. (U.K.)

  14. Nuclear non-proliferation: a guide to the debate

    International Nuclear Information System (INIS)

    Goldblat, Jozef.

    1985-01-01

    The non-proliferation policies of 15 countries have been studied and summarized for use by participants of the third Review Conference of the Parties to the Treaty on the Non-Proliferation (NPT) of Nuclear weapons held in September 1985. The main purpose of the guide is to examine what action must be taken to ensure the Treaty's survival. There are four chapters following an introduction, covering the implementation of the essential provisions of the NPT, the motivations of the countries which have not joined the NPT, together with the motivations of those which have formally renounced the possession of nuclear weapons, even though they possess the technical and economic potential necessary to manufacture them. The last chapter summarises measures which might be taken to strengthen the NPT including ideas put forward at a workshop held in 1984. (author)

  15. Cell kinetics of irradiated experimental tumors: cell transition from the non-proliferating to the proliferating pool

    International Nuclear Information System (INIS)

    Potmesil, M.; Goldfeder, A.

    1980-01-01

    In murine mammary carcinomas, parenchymal tumor cells with dense nucleoli traverse the cell cycle and divide, thus constituting the proliferating pool. Cells with trabeculate or ring-shaped nucleoli either proceed slowly through G 1 phase or are arrested in it. The role of these non-proliferating, G 1 phase-confined cells in tumor regeneration was studied in vivo after a subcurative dose of X-irradiation in two transplantable tumor lines. Tumor-bearing mice were continuously injected with methyl[ 3 H]thymidine before and after irradiation. Finally, the labeling was discontinued, mice injected with vincristine sulfate and cells arrested in metaphase were accumulated over 10-hrs. Two clearly delineated groups of vincristine-arrested mitoses emerged in autoradiograms prepared from tumor tissue at the time of starting tumor regrowth: one group with the silver-grain counts corresponding to the background level, the other with heavily labeled mitoses. As the only source of unlabeled mitoses was unlabeled G 1 phase-confined cells persisting in the tumor, this indicated cell transition from the non-proliferating to the proliferating pool, which took place in the initial phase of the tumor regrowth. Unlabeled progenitors have apparently remained in G 1 phase for at least 5-12 days after irradiation. (author)

  16. Brazil and Mexico in the Nonproliferation Regime, Common Structures and Divergent Trajectories in Latin America

    OpenAIRE

    Sotomayor, Arturo C.

    2014-01-01

    Chapter 8 There are multiple options Latin American countries to support and comply with the nuclear nonproliferation regime. At the global level, states can decide to ratify the core treaties and join their supporting institutions such as the Treaty on the Non-Proliferation of Nuclear Weapons (NPT), the International Atomic Energy Agency (IAEA), the Comprehensive Nuclear-Test-Ban Treaty (CTBT), the Nuclear Suppliers Group (NSG), the Missile Technology Control Regime, the...

  17. Back-end of the fuel cycle and non-proliferation strategies

    Energy Technology Data Exchange (ETDEWEB)

    Chebeskov, A.N.; Oussanov, V.I.; Iougai, S.V.; Pshakin, G.M. [Institute of Physics and Power Engineering, State Scientific Center of Russian Federation, Obninsk (Russian Federation)

    2001-07-01

    The paper focuses on the problem of fissile materials proliferation risk estimation. Some methodological approaches to the solution of this task and results of their application for comparison of different nuclear fuel cycle strategies are discussed. The results of comparative assessment of non-proliferation aspects of plutonium utilization alternatives in Russia using system analysis approach are presented. (author)

  18. Back-end of the fuel cycle and non-proliferation strategies

    International Nuclear Information System (INIS)

    Chebeskov, A.N.; Oussanov, V.I.; Iougai, S.V.; Pshakin, G.M.

    2001-01-01

    The paper focuses on the problem of fissile materials proliferation risk estimation. Some methodological approaches to the solution of this task and results of their application for comparison of different nuclear fuel cycle strategies are discussed. The results of comparative assessment of non-proliferation aspects of plutonium utilization alternatives in Russia using system analysis approach are presented. (author)

  19. The Non-Proliferation Treaty and the peaceful use of nuclear energy

    International Nuclear Information System (INIS)

    Wilmshurst, M.J.

    1983-01-01

    The author discusses the reasons of criticism and even rejection of the Non-Proliferation Treaty of 1968, dealing in particular with the alledged discriminating nature of the Treaty and with the statement that the Treaty is not apt to prevent proliferation on a vertical plane. He further discusses the motives behind the efforts of potential nuclear weapons states to get nuclear weapons. The system of worldwide and bilateral safeguards and controls covering the transfer of nuclear technologies is explained. In conclusion the author suggests to pay more attention to article IV, sub-section (2) of the Non-Proliferation Treaty as this might offer a suitable approach to restricting the dissemination of nuclear explosives. (HP) [de

  20. 'For good and for bad': the relations between universal obligations and particular efforts in the field of nuclear non-proliferation

    International Nuclear Information System (INIS)

    Dassen Van, L.

    2005-01-01

    Full text: The world has 'nuclear non-proliferation' on its lips. Presidents, politicians, journalists and others refer to it as the number one peril in our times. This may be right or wrong but irrespective of the real salience of 'nuclear dangers' it has a grip on our minds and wallets. A long range of states now make active investments in the improvement of nuclear security; not only at home as they used to do, but even abroad in other places and countries where there is concern with regard to how safe nuclear and materials are kept and stored. This development is surely an expression of a shared broadening of our sense of responsibility beyond the narrow confines of statehood and borders, and therefore this development should please us. On the other hand, the truly universal measures and instruments of the NPT and the regime round it are in trouble. It is being stated in some quarters that the NPT is inadequate in a new era with new threats from sub-state actors. Nevertheless, the NPT is the only legal instrument that is a framework that either by itself or as a starting-point can serve as a tool box for long-term storage of the proliferation risks. The reason for this is that the NPT is an expression of fairness in terms of rights and balances for all states committed to non-proliferation. And its foundations are those of international law. To the extent the NPT is being questioned will there also be a risk that non-proliferation efforts in the framework of cooperative threat reduction and for instance global partnership will lose legitimacy; simply for the reason that only a small number of the non-proliferation concerns are given attention. This relationship between cooperative threat reduction efforts on the one hand and universal legal instruments for non-proliferation on the other is a double-edged sword. While the two can reinvigorate and strengthen each other, there is also a risk that the one - cooperative threat reduction - when given preference over

  1. Nuclear proliferation: Some context and consequences

    International Nuclear Information System (INIS)

    Ford, C. A.

    2007-01-01

    The article addressed the importance of nonproliferation and supporting and reinforcing nonproliferation commitments. The most important benefit of the NPT has been in its contribution to the security of individual states party, as well as to regional and international security, through the obligations which help to prevent any further proliferation of nuclear weapons. The NPT therefore powerfully augments the national security of every state party, and not merely just the NPT nuclear weapons states. Indeed, it is the countries of the developing world, as well as many other non-nuclear weapon states, that could suffer the most in security terms if a non-nuclear weapons state in the developing world suddenly acquired T he Bomb a nd became emboldened to engage in threats and adventurism against its neighbors. The nonproliferation regime hinges upon the steps that all countries take on their own and with like-minded allies to further nonproliferation goals - and whether the international community can successfully shape the calculations of present-day and future would-be proliferation in useful ways. The nonproliferation regime, therefore, includes not just the NPT and other legally-binding obligations but complex dynamics of persuasion and deterrence that employ many different tools. The NPT helps establish the core nonproliferation obligations toward which many of the tools in the international community's tool kit are directed.

  2. Proliferation Control Regimes: Background and Status

    Science.gov (United States)

    2012-10-25

    States has signed such agreements with Antigua and Barbuda, the Bahamas, Belize, Croatia, Cyprus, Liberia, Malta, the Marshall Islands , Mongolia...Chemical Weapons Convention (CWC), the Biological and Toxin Weapons Convention (BWC), and the Australia Group. The informal Australia Group...biological agents or toxins “of types and in quantities that have no justification for peaceful purposes.” The missile nonproliferation regime is founded not

  3. Regime shifts under forcing of non-stationary attractors: Conceptual model and case studies in hydrologic systems.

    Science.gov (United States)

    Park, Jeryang; Rao, P Suresh C

    2014-11-15

    We present here a conceptual model and analysis of complex systems using hypothetical cases of regime shifts resulting from temporal non-stationarity in attractor strengths, and then present selected published cases to illustrate such regime shifts in hydrologic systems (shallow aquatic ecosystems; water table shifts; soil salinization). Complex systems are dynamic and can exist in two or more stable states (or regimes). Temporal variations in state variables occur in response to fluctuations in external forcing, which are modulated by interactions among internal processes. Combined effects of external forcing and non-stationary strengths of alternative attractors can lead to shifts from original to alternate regimes. In systems with bi-stable states, when the strengths of two competing attractors are constant in time, or are non-stationary but change in a linear fashion, regime shifts are found to be temporally stationary and only controlled by the characteristics of the external forcing. However, when attractor strengths change in time non-linearly or vary stochastically, regime shifts in complex systems are characterized by non-stationary probability density functions (pdfs). We briefly discuss implications and challenges to prediction and management of hydrologic complex systems. Copyright © 2014 Elsevier B.V. All rights reserved.

  4. South America and the proliferation of biological weapons

    OpenAIRE

    Tatiana Coutto

    2013-01-01

    This article focuses on the role of regional institutions and political practices in strengthening multilateral disarmament and non-proliferation regimes. Particular attention is devoted to coordination between Brazil and Argentina with a view to forging a "South American position" vis-à-vis the Biological and Toxins Weapons Convention (BTWC). Empirical evidence suggests that informal arrangements between the two countries were capable of involving other South American leaders and promoting t...

  5. Non-proliferation and nuclear data

    International Nuclear Information System (INIS)

    Sowerby, M.G.

    1978-01-01

    A review is made of the problem of the proliferation of nuclear weapons with particular emphasis on proliferation and nuclear power. Some indications of the nuclear data requirements associated with methods of reducing proliferation risks are presented

  6. Current nuclear non-proliferation policies in the world

    International Nuclear Information System (INIS)

    Kurosawa, Mitsuru

    1997-01-01

    Although a global nuclear confrontation between the U.S. and the Soviet Union has disappeared, many challenges to nuclear non-proliferation have emerged. Sources of concern, like a nuclear weapon program by Iraq and suspicions of North Korea have caused the adoption of a variety of political and technical measures in order to meet these challenges in the post-Cold War era. This paper describes the following ten policies for non-proliferation: 1) Strengthening the NPT; 2) Nuclear reduction; 3) CTBT and cut-off treaty; 4) Establishment of NWFZs; 5) Counterproliferation; 6) Strengthening the IAEA Safeguards; 7) Control and disposal of nuclear material from dismantled nuclear weapons; 8) Export control; 9) Registration of plutonium; and 10) Actions against nuclear smuggling. The first four measures can be said to be mainly political policies, the fifth measure (counterproliferation), can be categorized as basically a military policy, and the last five measures can be said to be technical. (J.P.N.)

  7. Nuclear Non-Proliferation and Export Control in the Republic of Croatia

    International Nuclear Information System (INIS)

    Valcic, I.; Prah, M.; Mikec, N.

    2006-01-01

    In accordance with its internationally accepted obligations, the Republic of Croatia is actively implementing principles of non-proliferation and export control of nuclear materials and/or equipment. The article deals with treaties, conventions, agreements and other international arrangements that are creating certain obligation for Republic of Croatia related to nuclear non-proliferation. The most important are the Treaty on the Non-proliferation of Nuclear Weapons, the Convention on the Physical Protection of Nuclear Material, the Agreement between the Republic of Croatia and the International Atomic Energy Agency for the Application of Safeguards with Protocol, the Protocol Additional to the Agreement Between the Republic of Croatia and the International Atomic Energy Agency for the Application of Safeguards, the Comprehensive Nuclear Test-Ban Treaty, the NSG Guidelines for the Export of Nuclear Material, Equipment and Technology and NSG Guidelines for Transfers of Nuclear-Related Dual-Use Equipment, Materials, Software and Related Technology. In addition the article describes a national regulative framework, the basis for conducting activities in nuclear material control, export control of dual-use items as well as non-proliferation of the weapons of mass destruction. Details are given about the Nuclear Safety Act, the Act on Liability for Nuclear Damage, the Act on Export of Dual-Use Items, the Decree on the List of Dual-Use Items, the Law on Production, Repair and Trade in Arms and Military Equipment and the Decree specifying goods subject to export and import licenses. (author)

  8. Experience of Republic of Macedonia in Providing WMD Non-Proliferation Policy

    International Nuclear Information System (INIS)

    Mecinovic, S.

    2007-01-01

    The Republic of Macedonia as a country in transition and as a country which does not posses WMD, has accepted to developed and implemented non-proliferation policy of WMD. First of all, we accepted the definition of WMD as used in international agreements, conventions and protocol and WMD includes nuclear, biological and toxin weapons, agent and precursors. WMD in wide sense includes all toxic chemical substances if they are used as means of attack or if they are the target of attack, all microorganisms and their product, all industrial facilities that use toxic chemicals in their process of production, transport and stockpile if they are a target of military or terrorist attack. For WMD non-proliferation projects to be valid, they must be on the level and carry the weight of international policy and doctrine and involve a most comprehensive sphere of the scientific and professional communities. This is only way to implement the projects in country such is Republic of Macedonia where the public opinion is that WMD are not real security problem because we neither possess nor seek to posses these kinds of weapons. Our WMD non-proliferation policy is tied to control of weapons, agents, precursors, technology and their transfer, market and possibility of use. Because of that we try to control know terrorist organization, groups and individuals. Terrorism caused special concern and attention, particularly when we talk about terrorism with NBC weapons and radiological, chemical and biological warfare agents. Scientific and technological progress led to fact that the instruments for performing terrorism (including WMD) can be produced or procured much easier than before. Rising industry which uses toxic chemicals and microorganisms in the production process created a lot of potential targets for terrorism actions in which they can use be as a target and an executive instrument. The new goal of contemporary treats is safety of life environment, which today includes

  9. Testing QCD in the non-perturbative regime

    Energy Technology Data Exchange (ETDEWEB)

    A.W. Thomas

    2007-01-01

    This is an exciting time for strong interaction physics. We have a candidate for a fundamental theory, namely QCD, which has passed all the tests thrown at it in the perturbative regime. In the non-perturbative regime it has also produced some promising results and recently a few triumphs but the next decade will see enormous progress in our ability to unambiguously calculate the consequences of non-perturbative QCD and to test those predictions experimentally. Amongst the new experimental facilities being constructed, the hadronic machines at JPARC and GSI-FAIR and the 12 GeV Upgrade at Jefferson Lab, the major new electromagnetic facility worldwide, present a beautifully complementary network aimed at producing precise new measurements which will advance our knowledge of nuclear systems and push our ability to calculate the consequences of QCD to the limit. We will first outline the plans at Jefferson Lab for doubling the energy of CEBAF. The new facility presents some wonderful opportunities for discovery in strong interaction physics, as well as beyond the standard model. Then we turn to the theoretical developments aimed at extracting precise results for physical hadron properties from lattice QCD simulations. This discussion will begin with classical examples, such as the mass of the nucleon and ?, before dealing with a very recent and spectacular success involving information extracted from modern parity violating electron scattering.

  10. Non-proliferation policies and demand for uranium

    International Nuclear Information System (INIS)

    Warnecke, S.J.

    1978-01-01

    The non-proliferation policies of USA, Canada and Australia are outlined, and the effects on nuclear policy in the consumer countries, particularly the member states of the European Community and Japan are considered. Supply and demand in relation to uranium, security and economic aspects are covered. Reprocessing, the use of plutonium in breeder reactors, and the wider issues of international confidence and trade are discussed. (U.K.)

  11. U.S. Proliferation Policy and the Campaign Against Transnational Terror: Linking the U.S. Non-Proliferation Regime to Homeland Security Efforts

    Science.gov (United States)

    2013-12-01

    virulent strains escaping from laboratories with inadequate biosecurity and biosafety regimes into a world with insufficient public health surveillance...Unclassified 19. SECURITY CLASSIFICATION OF ABSTRACT Unclassified 20. LIMITATION OF ABSTRACT UU NSN 7540–01–280–5500 Standard Form 298 (Rev. 2–89...of codification and legal measures to stop terrorist use and to a lesser degree to the international double standard on beliefs regarding the

  12. Which future for nuclear counter-proliferation?

    International Nuclear Information System (INIS)

    Duval, M.

    2010-01-01

    Dealing with the case of nuclear weapons possessed by nuclear states (but not eventually by terrorists), the author first identifies the constants of counter-proliferation: it is linked to interest conflicts between those who try to preserve their monopoly and those who try to acquire a new weapon either because of a threat or for reasons of regional prestige, the evolution from use to deterrence, the appearance of new actors after the USA and Russia, the role of nuclear tactical weapons, and the future of Russian weapons and know-how. He presents the international counter-proliferation context: the Non Proliferation Treaty (NPT), the IAEA and its controls, the Nuclear Supplier Group (NSG), the nuclear-free zones, the Comprehensive Test Ban Treaty (CTBT), the Missile Technology Control Regime (MTCR). He describes how and why proliferation occurs: uranium enrichment and plutonium technology, political reasons in different parts of the world. Then, he gives an overview of the proliferation status by commenting the cases of Israel, Iraq, India, Pakistan, North Korea, and Iran. He discusses the future of proliferation (involved countries, existence of a nuclear black market) and of counter-proliferation as far as Middle-East and North Korea are concerned. He tries finally to anticipate the consequences for nuclear deterrence strategy, and more particularly for Europe and France

  13. Optimization of the THz radiation from superconductor at non-laminar regime

    Energy Technology Data Exchange (ETDEWEB)

    Hosseini, Mehdi, E-mail: hosseini@sutech.ac.ir

    2016-10-15

    Highlights: • The terahertz radiation of a mesa structure at non laminar regime is considered here. • The non-laminarity of this media is modeled. • The equation of vortex motion and electromagnetic field is solved. • The radiated power is obtained and the parameter optimization for maximize the radiated power is done. - Abstract: The THz radiation due to the flux flow in a superconductor slab at non-laminar regime has been investigated and the radiated power spectrum has been calculated. The parameter (τ) is defined to show amount of non-laminarity. The results reveal that for small values of τ, the system radiated at the harmonics of famous washboard frequency. However, for large values of τ, the radiation spectrum will be changed and for extreme values of τ, the peaks will be flat. Therefore the washboard picture is not valid anymore. The results show that the radiation power is optimum for the special value of τ. Also, the results compared with other theoretical and experimental data.

  14. The safety regime concerning transboundary movement of radioactive waste and its compatibility with the trade regime of the WTO

    International Nuclear Information System (INIS)

    Strack, L.

    2004-01-01

    There is now extensive international law which regulates or prohibits the transboundary movement of radioactive waste. It seems likely that the trade restrictive provisions of the safety regime could be justified under the scope of Article X XI or X X GATT(general agreement on tariffs and trade). If a legitimate non proliferation issue were involved it is likely that any WTO (world trade organization) dispute settlement organ would allow governments the use of exceptions. Thus, the emerging international radioactive waste regime seems reconcilable under the WTO system. However, further clarification by the political, not the dispute settlement, institutions of the WTO would remove any remaining uncertainty by reaffirming the requirements of current law. Achieving sustainable development requires a coherent framework of global environment and economic governance. (N.C.)

  15. Non-proliferation and the control of atomic energy

    International Nuclear Information System (INIS)

    Goldschmidt, B.

    1977-01-01

    The non-proliferation problem has never ceased to haunt and to influence those responsible for the development of atomic energy. During and after the Second World War, Anglo-American co-operation was reflected in restrictions on the exchange of enrichment and reprocessing know-how. Between 1945 and 1955, the Anglo-Saxon powers continued with the policy of secrecy and uranium monopoly decided on in 1943 at the Quebec summit conference. Starting in 1955, the failure of this policy led - at the suggestion of the United States of America - to a freer flow of information and to the creation of the International Atomic Energy Agency with its safeguards, which permitted widespread application of the policy of technical assistance subject to controls and widespread commerce in research and power reactors - mainly fuelled with enriched uranium and manufactured in the USA. There followed periods characterized by general legal blocks, with two unilateral renunciation treaties - the Partial Test Ban Treaty of 1963, covering non-underground tests, and the Treaty on the Non-Proliferation of Nuclear Weapons, of 1968, covering nuclear explosive devices and the entire fuel cycle. The Indian atomic explosion and the acceleration of nuclear programmes owing to the oil crisis prompted - in 1974 - efforts by supplier countries to limit the transfer of sensitive technology and the possession of plants capable of producing substances which could be used in the production of nuclear weapons; the USA has even proposed the curtailment of plutonium extraction and of breeder construction, although these are considered by many countries to be essential to the independence of their energy development programmes. This policy of reserving the sensitive stages of the fuel cycles to a few advanced countries and the questioning of existing nuclear agreements have created, in the relations between supplier and recipient countries, a regrettable intensification of the distrust which must be dispelled

  16. International aspects of non-proliferation policy

    International Nuclear Information System (INIS)

    Aucoin, P.A.

    1978-01-01

    There are currently two areas on the national scene and one on the international scene that require immediate attention. The first is relief under contracts for enrichment services, an area in which the US can still demonstrate its desire to become a stable and continuous source of supply. The second national area is the Nuclear Non-Proliferation Act of 1977. The United States must proceed very cautiously, however, for if discretion and very careful judgment are not used, the Act will immediately be branded as a blatant effort on the part of the US to control the energy options of other sovereign states. The international area is that of the International Nuclear Fuel Cycle Evaluation program. This medium exists for wise and deliberate growth of a commercial nuclear power program which can serve the global community. The next three years probably allow one remaining chance for successful containment of weapons proliferation. If we do not recognize the rights of every sovereign state to voluntarily participate and agree, we, as members of the global community, will have failed

  17. Position paper on nuclear proliferation issues preventing nuclear proliferation. A duty for the nuclear community

    Energy Technology Data Exchange (ETDEWEB)

    Goldschmidt, Pierre; Bonin, Bernard [ENS High Scientific Council, Brussels (Belgium)

    2010-06-15

    The production of electricity from nuclear power plants is widely seen today as having an increasing role to play in meeting global energy requirements in a sustainable manner. Conscious of the inherently sensitive nature of nuclear technology and materials the ENS-HSC (European Nuclear Society - High Scientific Council) is well aware that a severe safety, security, environmental or proliferation mishap stemming from nuclear energy anywhere in the world would undermine the potential for nuclear energy to contribute to the global energy supply and the minimization of harmful carbon emissions. While the safety of nuclear power plants has continuously improved over the last three decades, the same degree of success cannot be claimed when it comes to the achievements of the international community in stemming the risk of nuclear weapons proliferation. This unfortunate situation is due to both technical and political reasons. The European nuclear industry is committed to the exclusively peaceful use of nuclear energy and to export nuclear facilities and related materials, equipment and technology solely in accordance with relevant national export laws and regulations, Nuclear Suppliers Group guidelines and pertinent United Nations Security Council Resolutions. The ENS-HSC considers that, as a manifestation of their strong commitment to nonproliferation, it is important for the nuclear industry to pay special attention to and promote proliferation-resistant designs and to take IAEA safeguards requirements into account at the design stage. Preventing nuclear proliferation is primarily the responsibility of states but, as major stakeholders, the nuclear industry and scientific community should actively support nuclear disarmament as foreseen in the Non-Proliferation Treaty and measures necessary to strengthen the non-proliferation regime, particularly the international control of the flux of nuclear material and technology. (orig.)

  18. Position paper on nuclear proliferation issues preventing nuclear proliferation. A duty for the nuclear community

    International Nuclear Information System (INIS)

    Goldschmidt, Pierre; Bonin, Bernard

    2010-01-01

    The production of electricity from nuclear power plants is widely seen today as having an increasing role to play in meeting global energy requirements in a sustainable manner. Conscious of the inherently sensitive nature of nuclear technology and materials the ENS-HSC (European Nuclear Society - High Scientific Council) is well aware that a severe safety, security, environmental or proliferation mishap stemming from nuclear energy anywhere in the world would undermine the potential for nuclear energy to contribute to the global energy supply and the minimization of harmful carbon emissions. While the safety of nuclear power plants has continuously improved over the last three decades, the same degree of success cannot be claimed when it comes to the achievements of the international community in stemming the risk of nuclear weapons proliferation. This unfortunate situation is due to both technical and political reasons. The European nuclear industry is committed to the exclusively peaceful use of nuclear energy and to export nuclear facilities and related materials, equipment and technology solely in accordance with relevant national export laws and regulations, Nuclear Suppliers Group guidelines and pertinent United Nations Security Council Resolutions. The ENS-HSC considers that, as a manifestation of their strong commitment to nonproliferation, it is important for the nuclear industry to pay special attention to and promote proliferation-resistant designs and to take IAEA safeguards requirements into account at the design stage. Preventing nuclear proliferation is primarily the responsibility of states but, as major stakeholders, the nuclear industry and scientific community should actively support nuclear disarmament as foreseen in the Non-Proliferation Treaty and measures necessary to strengthen the non-proliferation regime, particularly the international control of the flux of nuclear material and technology. (orig.)

  19. U.S. - India nuclear cooperation and non-proliferation

    International Nuclear Information System (INIS)

    Yash Thomas, Mannully

    2008-01-01

    The agreement for cooperation between the Government of the United States of America and the government of India concerning peaceful uses of nuclear energy (referred as 123 agreement) acknowledges a shift in international strategies and relations in both countries. As to India, it marks the end of nuclear isolation resulting from constraint, embargoes and controls and instead opens the path for nuclear commerce. With respect to the United States it entails a major geo strategic ally in the evolving South Asia region and promises large commercial benefits to the US nuclear sector. This is called 'nuclear deal' and constitutes one of the major political, economic and strategic relationship developing between the two countries since 2001. It will lead to the separation of military and civilian nuclear installations in India, the latter to be placed under the safeguards system of the International Atomic Energy Agency (IAEA). It thus, de facto accepts India in the club of nuclear weapon states within the meaning of the Treaty on the non-proliferation of nuclear weapons (NPT) although it is not party to this treaty, refuses adhering to it, officially possesses nuclear weapons and is not subject to a comprehensive system of safeguards. This article will examine the developments which led to the 123 agreement and its subsequent implementation in a wider context of international relations and non proliferation. First, the articles gives a brief introduction into the Indian nuclear programme, the legislative framework and the factors which necessitated nuclear cooperation between India and the United States. Secondly, it will address the implementation of the nuclear deal and subsequent developments. Finally, it will analyse the non proliferation issues related to the implementation of the agreement. (N.C.)

  20. Nuclear non-proliferation: Global security in a rapidly changing world. Carnegie International Non-Proliferation Conference, 21 June 2004, Washington, DC, USA

    International Nuclear Information System (INIS)

    ElBaradei, M.

    2004-01-01

    This statement outlines what the IAEA and the international community has learned, what are the problems faced and the nature of the required reforms in the field of non-proliferation, security, safeguards inspection. The proposals are mostly fucued on international/collective cooperation in arms control, improvements of security and effectiveness of safeguards

  1. Nuclear non-proliferation: Global security in a rapidly changing world. Carnegie International Non-Proliferation Conference, 21 June 2004, Washington, DC, USA

    Energy Technology Data Exchange (ETDEWEB)

    ElBaradei, M

    2004-06-21

    This statement outlines what the IAEA and the international community has learned, what are the problems faced and the nature of the required reforms in the field of non-proliferation, security, safeguards inspection. The proposals are mostly fucued on international/collective cooperation in arms control, improvements of security and effectiveness of safeguards.

  2. A Study on the cooperation policy in multilateral nuclear control regimes and the advancing of national export control system

    International Nuclear Information System (INIS)

    Lee, Byung Wook; Oh, K. B.; Yang, M. H.; Lee, H. M.; Lee, K. S.; Ko, H. S.; Ryu, J. S.; Kim, J. S.

    2004-08-01

    This study carried out the analysis of trends of the multilateral nuclear control in four aspects. First, this study analyzes the past trends of the international nuclear non-proliferation regime, which includes the NPT, the IAEA safeguards system, the international nuclear export control regime and the physical protection of nuclear materials. Second, this study establishes the multilateral cooperation strategies for the effective cooperation in the process of strengthening the nuclear control regimes. Third, this study reviews the major agenda of nuclear control regimes and establishes national positions on each agenda. Fourth, this study also analyzes outstanding issues in nuclear control regimes and derives some factors to reflect national nuclear control system

  3. 1995 - a pivotal year for nuclear nonproliferation. German nonproliferation policy in the runup to the extension of the Non-Proliferation Treaty

    International Nuclear Information System (INIS)

    Preisinger, J.

    1994-01-01

    The paper describes the non-proliferation as a task of preventive security policy, the non-proliferation instruments, the content of an extended non-proliferation system, and tasks of German non-proliferation policy. (DG)

  4. Finland and nuclear non-proliferation: The evolution and cultivation of a norm

    International Nuclear Information System (INIS)

    Dassen, L. van

    1998-03-01

    Finland''s entrance on the non-proliferation scene was in 1963 when President Kekkonen suggested a Nordic nuclear-weapons-free zone (NWFZ). This started a debate in and among the Nordic countries and it created a Finnish profile towards the Soviet Union. In most cases, the Soviets tried to bring Finland into a much closer relationship with the USSR. The mere prospect and debate on a Nordic NWFZ reduced the incentive for the Soviets to undermine Finnish neutrality or their desire to suggest consultations according to the Treaty of Friendship, Cooperation and Mutual Assistance on military assistance in the case of a threat to Soviet and/or Finnish security. During the negotiations on the Non-Proliferation Treaty, 1965-1968, Finland played a very active role as a bridge-builder, first between the superpowers and later between the developed and the developing world. This activity gave Finland a name in the UN, strengthened its neutrality and established good relations with the West as well. In 1978, Kekkonen brought up the Nordic NWFZ once more, this time under influence of certain strategic challenges to Finland and general East-West developments. In this Kekkonen had much backing by the public in Finland whereas other states reacted very reluctantly. Politics in Finland has to a large extent been marked by the relations with Russia and later the Soviet Union. However, nuclear non-proliferation was used to ease the weight of this imposing neighbour; a strategy that certainly must be regarded as successful. While achieving this, it was also possible to increase contacts with western states and remain accepted as a neutral state. For Finland, non-proliferation policy was initially a suitable issue to solve other problems than those related exclusively to proliferation. But it was also a policy with a high degree of persistence, pragmatism and willingness to work with concrete issues that maybe do not reach the international limelight in the short run but that work in

  5. Finland and nuclear non-proliferation: The evolution and cultivation of a norm

    Energy Technology Data Exchange (ETDEWEB)

    Dassen, L. van [Uppsala Univ. (Sweden). Dept. of Peace and Conflict Research

    1998-03-01

    Finland``s entrance on the non-proliferation scene was in 1963 when President Kekkonen suggested a Nordic nuclear-weapons-free zone (NWFZ). This started a debate in and among the Nordic countries and it created a Finnish profile towards the Soviet Union. In most cases, the Soviets tried to bring Finland into a much closer relationship with the USSR. The mere prospect and debate on a Nordic NWFZ reduced the incentive for the Soviets to undermine Finnish neutrality or their desire to suggest consultations according to the Treaty of Friendship, Cooperation and Mutual Assistance on military assistance in the case of a threat to Soviet and/or Finnish security. During the negotiations on the Non-Proliferation Treaty, 1965-1968, Finland played a very active role as a bridge-builder, first between the superpowers and later between the developed and the developing world. This activity gave Finland a name in the UN, strengthened its neutrality and established good relations with the West as well. In 1978, Kekkonen brought up the Nordic NWFZ once more, this time under influence of certain strategic challenges to Finland and general East-West developments. In this Kekkonen had much backing by the public in Finland whereas other states reacted very reluctantly. Politics in Finland has to a large extent been marked by the relations with Russia and later the Soviet Union. However, nuclear non-proliferation was used to ease the weight of this imposing neighbour; a strategy that certainly must be regarded as successful. While achieving this, it was also possible to increase contacts with western states and remain accepted as a neutral state. For Finland, non-proliferation policy was initially a suitable issue to solve other problems than those related exclusively to proliferation. But it was also a policy with a high degree of persistence, pragmatism and willingness to work with concrete issues that maybe do not reach the international limelight in the short run but that work in

  6. Report of the international forum on nuclear energy, nuclear non-proliferation and nuclear security. Measures to ensure nuclear non-proliferation and nuclear security for the back end of nuclear fuel cycle and regional cooperation in Asia

    International Nuclear Information System (INIS)

    Tazaki, Makiko; Yamamura, Tsukasa; Suzuki, Mitsutoshi; Kuno, Yusuke; Mochiji, Toshiro

    2013-03-01

    The Japan Atomic Energy Agency (JAEA) held 'International Forum on Nuclear Energy, Nuclear Non-proliferation and Nuclear Security - Measures to ensure nuclear non-proliferation and nuclear security for the back end of nuclear fuel cycle and regional cooperation in Asia-' on 12 and 13 December 2012, co-hosted by the Japan Institute of International Affairs (JIIA) and School of Engineering, The University of Tokyo. In the forum, keynote speakers from Japan, International Atomic Energy Agency (IAEA), the U.S., France and Republic of Korea (ROK), respectively explained their efforts regarding peaceful use of nuclear energy and nuclear non-proliferation. In two panel discussions, entitled 'Measures to ensure nuclear non-proliferation and nuclear security of nuclear fuel cycle back end' and 'Measures to ensure nuclear non-proliferation and nuclear security for nuclear energy use in the Asian region and a multilateral cooperative framework', active discussions were made among panelists from Japan, IAEA, the U.S., France, ROK, Russia and Kazakhstan. This report includes abstracts of keynote speeches, summaries of two panel discussions and materials of the presentations in the forum. The editors take full responsibility for the wording and content of this report except presentation materials. (author)

  7. Preventing the spread of nuclear weapons : The law of arms control and the international non-proliferation regime

    NARCIS (Netherlands)

    Coppen, T.

    2016-01-01

    The proliferation of nuclear weapons remains a severe threat to international peace, security and stability. In order to counter this threat, the international community has taken numerous measures, legal and otherwise, resulting in a global framework of treaties and political agreements known as

  8. South America and the proliferation of biological weapons

    Directory of Open Access Journals (Sweden)

    Tatiana Coutto

    2013-04-01

    Full Text Available This article focuses on the role of regional institutions and political practices in strengthening multilateral disarmament and non-proliferation regimes. Particular attention is devoted to coordination between Brazil and Argentina with a view to forging a "South American position" vis-à-vis the Biological and Toxins Weapons Convention (BTWC. Empirical evidence suggests that informal arrangements between the two countries were capable of involving other South American leaders and promoting the exchange of information among different groups of states, most notably during the 2006 BTWC review conference. This paper also sheds light on the identification of specific features that allow for increasing visibility and actorness of regional powers in promoting universality of multilateral security regimes (MSR, as well as the limitations faced by these players.

  9. Primordial black holes in linear and non-linear regimes

    Energy Technology Data Exchange (ETDEWEB)

    Allahyari, Alireza; Abolhasani, Ali Akbar [Department of Physics, Sharif University of Technology, Tehran (Iran, Islamic Republic of); Firouzjaee, Javad T., E-mail: allahyari@physics.sharif.edu, E-mail: j.taghizadeh.f@ipm.ir [School of Astronomy, Institute for Research in Fundamental Sciences (IPM), P.O. Box 19395-5531, Tehran (Iran, Islamic Republic of)

    2017-06-01

    We revisit the formation of primordial black holes (PBHs) in the radiation-dominated era for both linear and non-linear regimes, elaborating on the concept of an apparent horizon. Contrary to the expectation from vacuum models, we argue that in a cosmological setting a density fluctuation with a high density does not always collapse to a black hole. To this end, we first elaborate on the perturbation theory for spherically symmetric space times in the linear regime. Thereby, we introduce two gauges. This allows to introduce a well defined gauge-invariant quantity for the expansion of null geodesics. Using this quantity, we argue that PBHs do not form in the linear regime irrespective of the density of the background. Finally, we consider the formation of PBHs in non-linear regimes, adopting the spherical collapse picture. In this picture, over-densities are modeled by closed FRW models in the radiation-dominated era. The difference of our approach is that we start by finding an exact solution for a closed radiation-dominated universe. This yields exact results for turn-around time and radius. It is important that we take the initial conditions from the linear perturbation theory. Additionally, instead of using uniform Hubble gauge condition, both density and velocity perturbations are admitted in this approach. Thereby, the matching condition will impose an important constraint on the initial velocity perturbations δ {sup h} {sub 0} = −δ{sub 0}/2. This can be extended to higher orders. Using this constraint, we find that the apparent horizon of a PBH forms when δ > 3 at turn-around time. The corrections also appear from the third order. Moreover, a PBH forms when its apparent horizon is outside the sound horizon at the re-entry time. Applying this condition, we infer that the threshold value of the density perturbations at horizon re-entry should be larger than δ {sub th} > 0.7.

  10. Course modules on nuclear safeguards and non-proliferation

    International Nuclear Information System (INIS)

    Bril, L.-V.; Janssens-Maenhout, G.

    2004-01-01

    Full text: One of major current concern in the nuclear field is the conservation of developed knowledge and expertise. The relevance of this subject is steadily increasing for several reasons: retirement of the generation of first industrial development of nuclear energy, only one new reactor under construction in Europe while several in Eastern and Asian countries, the public's concern on safety, radioactive waste and safeguards aspects, and some lack of interest common to many activities in engineering and physics. Moreover nuclear safeguards is nowadays characterised with an enlarged scope and no longer strictly limited to the accountancy of nuclear material; today it encompasses non proliferation of nuclear material, and deals with the control of dual use equipment and technologies, illicit trafficking and External Security. Some higher education networks, such as the European Nuclear Engineering Network (ENEN), have been established to make better use of dwindling teaching capacity, scientific equipment and research infrastructure, through co-operation amongst universities and research centres. The European Safeguards Research and Development Association (ESARDA) initiated the set-up of course modules under an e-learning medium, to preserve knowledge in nuclear safeguards. These course modules should be considered as basic pedagogical documentation, which will be accessible via the Internet. Monitoring or controlling of the accesses will be ensured. The modules are structured with an increasing level of detail, in function of the audience. On one hand the course modules should be attractive to University students in nuclear, chemical or mechanical engineering, in radiochemistry, statistics, law, political science etc. at universities or specialised institutes. On the other hand the course modules aim to give professionals, working on specific safeguards or non-proliferation issues an overview and detailed technical information on the wide variety of nuclear

  11. Non-alcoholic beverages, unknown influence on cell proliferation - an in vitro study.

    Science.gov (United States)

    Nowacki, Maciej; Adamowicz, Jan; Olkowska, Joanna; Pietkun, Katarzyna; Kloskowski, Tomasz; Bajek, Anna; Drewa, Tomasz

    2014-01-01

    The aim of the presented study was to check differences between 'Diet' and 'non-Diet' soft drinks on cell proliferation. Coca Cola and Pepsi Cola of different origin and their dietetic versions were examined at concentrations of 2% and 4%. Fructose and glucose as well as medium alone (control) were examined. Cell number was higher in media supplemented with soft drinks, compared to control. Proliferation depended on the soft drink concentration and its origin, but not on sugar and calorific content. An unknown factor is responsible for the increase in proliferation.

  12. Environmental effects of additional uranium development required by a non-proliferation policy

    International Nuclear Information System (INIS)

    Baca, T.E.; Scudella, G.

    1978-01-01

    New Mexico can expect to see an accelerated development of its uranium resources. The President's policy on non-proliferation will impact the degree and quantity of uranium ore mined. Environmental impacts are significant and are affected by the mining and milling phase more than any other aspect of the uranium fuel cycle. The state has begun evaluating the resource-associated impacts of uranium mining and milling, although very little reliable data are available. The information gathered, however, shows a need for state and Federal evaluation of both the impacts and the non-proliferation policy. 4 references

  13. On the Dynamic Robustness of a Non-Endoreversible Engine Working in Different Operation Regimes

    Directory of Open Access Journals (Sweden)

    Florencio Guzman-Aguilar

    2011-02-01

    Full Text Available In this work, we focused mainly in the analysis of stability of a non-endoreversible Curzon-Ahlborn engine working in an ecological regime. For comparison purposes we also include the Maximum Efficient Power (MEP regime taking into account the engine time delays. When the system’s dynamic stability is compared with its thermodynamics properties (efficiency and power output, we find that the temperature ratio τ = T1/T2 represents a trade-off between stability and energetic properties. When we take the non-endoreversible case, τ can increases to values greater than R (where R is the non-endoreversible parameter but not greater than one. We reformulate an important difference between this case and the other two, Maximum Power (MP and MEP regime, in which τ = R. Finally, we demonstrated that the total time delay does not destabilize the steady state of system. It does not seem to play a role in the dynamic thermodynamic property trade-off.

  14. Inhibition of proliferation, migration and invasion of human non ...

    African Journals Online (AJOL)

    Purpose: To determine the effect of phlomisoside F (PMF) on the proliferation, migration and invasion of human non-small cell lung cancer cell line A549 and explore the possible mechanisms. Methods: The anti-proliferative effect of PMF on A549 cells was determined by CCK-8. Subsequently, migration and invasion were ...

  15. Evaluation of the Administration's proposed nuclear non-proliferation strategy. Report to the Congress

    International Nuclear Information System (INIS)

    1977-01-01

    Dwindling supplies of fossil fuels are causing countries to turn increasingly to nuclear power as a major source of energy. Although nuclear power holds out the promise of energy independence, it has a formidable drawback--it can also lead to the proliferation of nuclear weapons. In April, the President announced a new policy designed to curb nuclear proliferation and the executive branch proposed legislation entitled 'The Nuclear Non-Proliferation Policy Act of 1977.' The strategy outlined in these documents calls for stricter export controls and safeguards as well as actions affecting uranium enrichment services, reprocessing, storing of spent fuel, and disposing of radioactive nuclear wastes. GAO analyzed this non-proliferation strategy as it relates to: Improving nuclear export controls; Strengthening international nuclear safeguards; Maintaining U.S. reliability as a supplier of uranium enrichment services; Deferring U.S. reprocessing of spent fuel as an example for others; Reducing risk of proliferation by controlling spent reactor fuel. In general, GAO concluded that the administration's strategy is constructive but noted some weaknesses which should be addressed. Some of the problems noted in this report may already have been addressed by congressional committees in their markup of the legislation

  16. Multidimensional Plasma Wake Excitation in the Non-linear Blowout Regime

    CERN Document Server

    Vieira, J.; Silva, L.O.

    2016-01-01

    Plasma accelerators can sustain very high acceleration gradients. They are promising candidates for future generations of particle accelerators for sev- eral scientific, medical and technological applications. Current plasma based acceleration experiments operate in the relativistic regime, where the plasma response is strongly non-linear. We outline some of the key properties of wake- field excitation in these regimes. We outline a multidimensional theory for the excitation of plasma wakefields in connection with current experiments. We then use these results and provide design guidelines for the choice of laser and plasma parameters ensuring a stable laser wakefield accelerator that maximizes the quality of the accelerated electrons. We also mention some of the future challenges associated with this technology.

  17. Treaty on the non-proliferation of nuclear weapons

    International Nuclear Information System (INIS)

    ElBaradei, M.

    2000-01-01

    The document reproduces the statement of the Director General of the IAEA to the Review Conference of the Treaty on the Non-Proliferation of Nuclear Weapons, New York, 24 April 2000. The speech focus on the IAEA activities relevant to the implementation of the Treaty, namely: verification through the IAEA safeguards, peaceful nuclear co-operation in the field of human health, food and agriculture, water resources management, environmental pollution monitoring, training

  18. THE ROLE AND RATIONALE OF THE NUCLEAR NON-PROLIFERATION TREATY IN THE TWENTY-FIRST CENTURY

    Directory of Open Access Journals (Sweden)

    Tom COPPEN

    2012-12-01

    Full Text Available Much has been written about perceived weaknesses of the NPT and the challenges it has been facing over the last decades. Analysing the most important provisions of the NPT, this article demonstrates how the treaty has managed to maintain its central role in the non-proliferation regime since its conclusion, and how it retains enough flexibility within its review mechanism and its managerial approach to supervision to keep this position for the decades to come. The theoretical framework of the article is formed by theory of arms control law, relevant features of which are: a large influence of politics and national interests of states on the rule of law; its flexible yet treaty-based nature; and the distinctive role of supervision in order to ensure compliance with primary rules. The article analyses key NPT provisions. Based on Article VIII, the NPT Review Conferences have both an important political and legal function. They are the NPT’s mechanism for review, implementation and supervision; in legal terms, they enable the evolution of the NPT based on subsequent agreement and practice. The NPT articles on non-proliferation and disarmament illustrate how the NPT has evolved to close off loopholes (Articles I and II and retains its flexibility whilst providing a global platform for negotiations on nuclear disarmament (Article VI. Article III evolved and must be understood to oblige NPT states to sign an Additional Protocol (AP with the IAEA. Article IV sets the parameters for the peaceful uses of nuclear energy, but leaves room for negotiation and conflict. The supervision of the NPT, illustrated by the case of Iran, is a complicated process involving international organisations such as the IAEA and the UNSC; while these may play important roles, however, the enforcement of the NPT is ultimately left to the NPT states themselves.

  19. JAEA's actions and contributions to the strengthening of nuclear non-proliferation

    Science.gov (United States)

    Suda, Kazunori; Suzuki, Mitsutoshi; Michiji, Toshiro

    2012-06-01

    Japan, a non-nuclear weapons state, has established a commercial nuclear fuel cycle including LWRs, and now is developing a fast neutron reactor fuel cycle as part of the next generation nuclear energy system, with commercial operation targeted for 2050. Japan Atomic Energy Agency (JAEA) is the independent administrative agency for conducting comprehensive nuclear R&D in Japan after the merger of Japan Atomic Energy Research Institute (JAERI) and Japan Nuclear Cycle Development Institute (JNC). JAEA and its predecessors have extensive experience in R&D, facility operations, and safeguards development and implementation for new types of nuclear facilities for the peaceful use of nuclear energy. As the operator of various nuclear fuel cycle facilities and numerous nuclear materials, JAEA makes international contributions to strengthen nuclear non-proliferation. This paper provides an overview of JAEA's development of nuclear non-proliferation and safeguards technologies, including remote monitoring of nuclear facilities, environmental sample analysis methods and new efforts since the 2010 Nuclear Security Summit in Washington D.C.

  20. Non-proliferation issues for the disposition of fissile materials using reactor alternatives

    International Nuclear Information System (INIS)

    Jaeger, C.D.; Duggan, R.A.; Tolk, K.M.

    1996-01-01

    The Department of Energy (DOE) is analyzing long-term storage imposition options for excess weapons-usable fissile materials. A number of the disposition alternatives are being considered which involve the use of reactors. The various reactor alternatives are all very similar and include front-end processes that could convert plutonium to a usable form for fuel fabrication, a MOX fuel fab facility, reactors to burn the MOX fuel and ultimate disposal of spent fuel in some geologic repository. They include existing, partially completed, advanced or evolutionary light water reactors and Canadian deuterium uranium (CANDU) reactors. In addition to the differences in the type of reactors, other variants on these alternatives are being evaluated to include the location and number of the reactors, the location of the mixed oxide (MOX) fabrication facility, the ownership of the facilities (private or government) and the colocation and/or separation of these facilities. All of these alternatives and their variants must be evaluated with respect to non-proliferation resistance. Both domestic and international safeguards support are being provided to DOE's Fissile Materials Disposition Program (FMDP) and includes such areas as physical protection, nuclear materials accountability and material containment and surveillance. This paper will focus on how the non-proliferation objective of reducing security risks and strengthening arms reduction will be accomplished and what some of the non-proliferation issues are for the reactor alternatives. Proliferation risk has been defined in terms of material form, physical environment, and the level of security and safeguards that is applied to the material. Metrics have been developed for each of these factors. The reactor alternatives will be evaluated with respect to these proliferation risk factors at each of the unit process locations in the alternative

  1. Plutonium: key issue in nuclear disarmament and non-proliferation of nuclear weapons

    International Nuclear Information System (INIS)

    Yoshisaki, M.B.

    1993-01-01

    The technical report is a 1993 update on weapons-grade plutonium, a key issue in nuclear disarmament. Its vital significance would again be discussed during the fifth and the last Review Conference on the Non-Proliferation Treaty (NPT) for Nuclear Weapons which would end in 1995. Member States shall decide whether an indefinite or conditional extension of NPT is necessary for world peace and international security. Two Non-NPT States, Russia and U.S.A. are in the forefront working for the reduction of nuclear weapons through nuclear disarmament. Their major effort is focused on the implementation of the Strategic Arms Reduction Treaty I and II or START I and II for world peace. The eventual implementation of START I and II would lead to the dismantling of plutonium from nuclear warheads proposed to be eliminated by both countries. This report gives three technical options to be derived from nuclear disarmament issues for the non-proliferation of nuclear weapons: (a) indefinite storage - there is no guarantee that these will not be used in the future (b) disposal as wastes - possible only in principle, because of lack of experience in mixing plutonium with high level wastes, and (c) source of energy - best option in managing stored weapons materials, because it satisfies non-proliferation objectives. It means fuel for energy in Light Water Reactors (LWR) or Fast Breeder Reactors (FBR). (author). 8 refs

  2. International Commission on Nuclear Non-Proliferation and Disarmament - A possible international regime to cover radiological materials

    International Nuclear Information System (INIS)

    Hautecouverture, Benjamin

    2009-10-01

    as radioactivity cannot be eliminated but only transferred from one place to another. Although it is difficult to give any precise figure, costs could in this case soar to trillions of dollars. The international community has begun concerning itself with nuclear and radiological terrorism officially since 9/11. In a rather unusual way in the field of international security, implementation of instruments to combat radiological terrorism anticipated the materialization of the risk. It is legitimate to ask oneself today if we have at our disposal an in-depth defence strategy, in which the many existing layers of action are integrated effectively. In the negative, it could be that a sense of false security proves more worrying and damageable than the threat itself. It is important to keep in mind that the international struggle against radiological terrorism necessitates long term efforts. IAEA, as an institution, appears to be, at least officially, the cornerstone of radiological safety and security. Although the initiatives of the Agency are based on the good will of Member States (action plans, code of conduct, recommendations, guides, partnerships, etc.), the inklings of an international regime on the issue have emerged, through iterated cooperation within the Agency. In this context, the risk of the emergence of a two-tier system, in which the bottom tier would be composed of comprehensive but ineffective mechanisms (multilateral awareness and non-binding or unverifiable tools), and the upper tier of fragmented and unbalanced ones ('coalition of like-minded' approach), is real. The project to move towards a more integrated regime to cover radiological materials thus seems a timely one. On a political level, five main issues at least must be addressed in order to establish a more comprehensive and effective international architecture for radiological and nuclear security: - integration and increased coherence necessitates financing and institutional authority (who

  3. Ultracentrifuge and non-proliferation

    International Nuclear Information System (INIS)

    Voortman, A.J.

    1977-01-01

    The author states that there is no meaningful difference, from the point of view of proliferation between peaceful, civil, scientific application of nuclear fission, and the use of it in nuclear weapons. The proliferation of the nuclear technology for weapons appeared and appears to be closely connected with the spread of peaceful applications of nuclear technology. In connection with this, he discusses the Ultracentrifuge plant at Almelo (Netherlands) and the supply of nuclear technology by West-Germany especially to Brazil. Further the changed American policy and the possibility of an American/Russian deal to prevent the spread of the nuclear enrichment technology is discussed

  4. Central fuel banking to reduce the number of proliferation sensitive enrichment activities

    International Nuclear Information System (INIS)

    Cserhati, A.

    2008-01-01

    Central fuel banking is a complex international political, economic and technical concept that aims to reduce uncontrolled spreading of uranium enrichment technology in the world in order to prevent proliferation of nuclear weapons. This paper first gives an outline of the notions: 'non-proliferation', the 'front-end' of the fuel cycle, the scope of fuel baking, nuclear fuel and the 60 years of enrichment technology. Enrichment technology is highly concentrated in the nuclear weapon states and other developed countries, but this is not exclusive any more. The technology is spreading. The global demand for enrichment services - parallel to massive nuclear investments in the civil sector and the ageing of older facilities - is constantly growing. Proliferation sensitivity calls for an effective and comprehensive non-proliferation regime. The solution may be multilateralizing the nuclear fuel cycle. After a historical overview, the proposals on multilateral nuclear approaches are presented. The assessment of the proposals is complex in the dimensions of: the non-proliferation aim, the assurance of supply aspect and other variables such as legal issues and non-nuclear inducements. A general evaluation and the recommendations of the Expert Panel of the IAEA are introduced outlining a plan on a middle- and long-term basis. The conclusion of the paper stresses the importance and challenge in finding the 'new balance' between obligations and interests of the members of the global community stating that the answers will have a significant impact on the nuclear indus- try, world wide economics and security policy. (orig.)

  5. Academic perspectives on the non-proliferation problem

    International Nuclear Information System (INIS)

    Gummett, P.

    1984-01-01

    The USA has demonstrated a greater penchant for a technical focus aimed at denial than any other state, despite a brief interlude under President Nixon and Dr. Kissinger when it displayed a total lack of concern about proliferation. This terminated with the sudden reawakening of interest following the Indian explosion and the announcement that the USA was not prepared to accept additional requests for uranium-enrichment services. According to Brenner, this enrichment crisis was engineered as a deliberate act of policy: yet this act of policy was unrelated to non-proliferation objectives. Rather, the Nixon administration's interest in privatisation in general, and commercialisation of enriched-uranium supply in particular, had led to a bureaucratic battle between the domestic side of the White House, the Atomic Energy Commission (AEC) and the Joint Committee on Atomic Energy (JCAE). This battle was totally unrelated to foreign policy: a situation not without precedent in this area. Nixon's Republican administration deliberately provoked a supply bottleneck by changing the terms of AEC supply contracts, with the intention of forcing the Democrat-dominated JCAE to agree to the entry of private industry into the uranium-enrichment business. The outcome was more dramatic than had been intended

  6. Nuclear weapons proliferation and the new world order

    International Nuclear Information System (INIS)

    Krause, J.

    1994-01-01

    The proliferation of nuclear weapons has become the priority safety problem since the end of the cold war. The danger that new nuclear states may arise from the former Soviet Union, the limited effectiveness of existing control systems, the increased attractiveness of nuclear weapons for countries in which a 'safety vacuum' has developed since the withdrawal of American and Russian forces, as well as the danger that additional nuclear states (China, India, Pakistan) may become unstable or disintegrate, make it necessary to explore and show the ensuing risks. The study contains analyses from well-respected experts from Germany, Russia, Japan and the USA. They show how the changes in regional security situations could lead to nuclear risks under certain circumstances, and the likely international consequences. A second point of emphasis consens the feasibility of new approaches or instruments in international non-proliferatic policy. New possibilities for the improvement of excisting control systems and the extension of international consensus on an intensification of the non-proliferation regime are offered by the changes in world politics. (orig.) [de

  7. The legal points at issue concerning the Non-proliferation Treaty and the verification agreement of EURATOM with the IAEA

    International Nuclear Information System (INIS)

    Zieger, G.

    1975-01-01

    An excellent and comprehensive but very juridicial contribution on: Development and content of the Non-proliferation Treaty, the problems which this Treaty poses for EURATOM (a common market, common supply, joint enterprises, Non-proliferation Treaty and France), the compatibility of the Non-proliferation Treaty with the EURATOM Treaty, verification agreement EURATOM - IAEA (the IAEA as the supervisory authority, the control system of the IAEA, guidelines elaborated by the IAEA to be used as the basis for negotiating safeguard agreements, national systems of accounting for and control of nuclear material IAEA supervision as a secondary control, principles of IAEA supervision, secrecy, conflict management), conclusion of the verification agreement, deviations from the guidelines elaborated by the IAEA to be used as the basis for negotiating safeguard agreements legal reflexions (verification agreement and Non-proliferation Treaty, reservations concerning the Non-proliferation Treaty, questions of competence between EURATOM and member states without nuclear weapons, problems of equal treatment). (HP/LN) [de

  8. Nuclear Non-Proliferation and Disarmament: Where Next?

    International Nuclear Information System (INIS)

    Evans, G.

    2013-01-01

    Let me come straight to the point: We are still at a real watershed with respect to the whole nuclear non-proliferation and disarmament project, about which hopes have been so high for most of the last two years, especially following the political breakthrough of the election of a US president totally committed to the ultimate achievement of a nuclear weapon-free world. Unless the key players in the international community, and there are many that matter in this context, not just the United States of America and the Russian Federation, get really serious about moving forward on the multiple critical agenda issues that face us - not just safeguards, the subject of this symposium, but right across the whole spectrum of non-proliferation, disarmament and peaceful-uses challenges - there is a very real danger that such remaining momentum for change as there is will stall, that the whole project will fall apart, and that we will be condemned to live for the indefinitely foreseeable future in a nuclear world that is very dangerous indeed. The prevailing sentiment after the May Nuclear Non-Proliferation Treaty (NPT) Review Conference was one of relief - that the conference had not broken down as it did in 2005 and that catastrophe had been avoided; in effect, that this particular watershed point had been passed. But the positive gains from that conference, when objectively assessed, were negligible on crucial NPT regime strengthening issues, and, with the possible exception of the agreement to hold a Middle East conference in 2012, very slight indeed elsewhere. And, weighing in the negative balance, there have been some serious disappointments on other key benchmark issues spelled out in US President Obama's April 2009 Prague Speech and on which real movement had been hoped for this year. Nothing has moved on Comprehensive Test Ban Treaty (CTBT) ratification by the USA or any other major nuclear power; negotiations on a fissile material cut-off treaty (FMCT) remain

  9. Report of “the 2013 international forum on peaceful use of nuclear energy, nuclear non-proliferation and nuclear security. Ensuring nuclear non-proliferation and nuclear security of nuclear fuel cycle options in consideration of the accident at TEPCO's Fukushima Daiichi Nuclear Power Station”

    International Nuclear Information System (INIS)

    Yamamura, Tsukasa; Suda, Kazunori; Tomikawa, Hirofumi; Suzuki, Mitsutoshi; Kuno, Yusuke; Mochiji, Toshiro

    2014-03-01

    The Japan Atomic Energy Agency (JAEA) held “International Forum on Peaceful Use of Nuclear Energy, Nuclear Non-proliferation and Nuclear Security – Ensuring Nuclear Non-Proliferation and Nuclear Security of Nuclear Fuel Cycle Options in consideration of the Accident at TEPCO's Fukushima Daiichi Nuclear Power Station –” on 3 and 4 December 2013, with the Japan Institute of International Affairs (JIIA) and School of Engineering, The University of Tokyo, as co-hosts. In the Forum, officials from Japan, the United States, France and International Atomic Energy Agency (IAEA) explained their efforts regarding peaceful use of nuclear energy and nuclear non-proliferation. Discussion was made in two panels, entitled “Nuclear non-proliferation and nuclear security measures of nuclear fuel cycle options in consideration of the Accident at TEPCO's Fukushima Daiichi Nuclear Power Station” and “Roles of safeguards and technical measures for ensuring nuclear non-proliferation for nuclear fuel cycle options”. In the first panel based on the implications of the Accident at TEPCO's Fukushima Daiichi Nuclear Power Station on the domestic and global nuclear energy use and increased interest in the back end of nuclear fuel cycle, discussion was made on nuclear non-proliferation and nuclear security challenges on both fuel cycle options from the policy and institutional viewpoints whereas in the second panel the roles of safeguards and proliferation resistant nuclear technology including plutonium burning technology in ensuring nuclear non-proliferation and nuclear security in the back end of nuclear fuel cycle were discussed. Officials and experts from Japan, IAEA, the United States, France and Republic of Korea participated in the panel and made contributions to active discussion. This report includes abstracts of keynote speeches, summaries of two panel discussions and materials of the presentations in the forum. The editors take full responsibility for the wording

  10. How we think about peace and security. The ABCs of initiatives for disarmament and non-proliferation education

    International Nuclear Information System (INIS)

    Toki, Masako; Potter, William C.

    2005-01-01

    Education and training are among the most important but underutilized tools for promoting disarmament and non-proliferation. Although few national governments or international organizations have invested significantly in such training programs, there is a growing recognition among States of the need to rectify this situation. This positive development is reflected in the broad support for recommendations of a UN study on Disarmament and Non-Proliferation Education and in related initiatives within the review process of the Nuclear Non-Proliferation Treaty (NPT). In view of the forthcoming 2005 NPT Review Conference, it is useful to take stock of the implementation of the UN study's recommendations. In particular, it is important to observe the progress that has been made within the context of the NPT review process, as well as the obstacles that must be overcome if the full potential for disarmament and non-proliferation education is to be realized. Resources on disarmament and non-proliferation education are increasingly available on the Internet. The UN Department for Disarmament Affairs has launched new features on its web site that include links to academic institutes, governmental centers, NGOs and other bodies engaged in educational efforts. As part of its mission to combat the spread of weapons of mass destruction (WMD) by training the next generation of nonproliferation specialists and raising global public awareness on WMD issues, the Center for Nonproliferation Studies (CNS) has developed a series of tutorials for non-proliferation and disarmament education. Among these tutorials, the NPT Tutorial has been designed to educate and provide useful material about the treaty through interactive text and enriched multimedia segments, including timelines, maps, and numerous links to relevant resources. Among other resources are teaching guides developed by the Monterey Institute's Center for Nonproliferation Studies through its Critical Issues Forum (CIF). More

  11. SIGMA: the novel approach of a new non-proliferating uranium enrichment technology

    International Nuclear Information System (INIS)

    Rivarola, M.; Florido, P.; Brasnarof, D.; Bergallo, E.

    2000-01-01

    The SIGMA concept, under development by Argentina, represents the evolution of the Uranium Enrichment Gaseous Diffusion technology, updated to face the challenge of the new economic-based and competitive world frame. The Enrichment technology has been historically considered as a highly proliferating activity in the nuclear field, and central countries limited the access of the developing countries to this technology. The SIGMA concept incorporates innovative proliferation resistant criteria at the beginning of the design process, and inherits all the non-proliferation features of the gaseous diffusion plants (GDPs). The radical new proliferation resistance approach of the SIGMA technology suggests a new kind of global control of the uranium enrichment market, where some developing countries might access an Enrichment plant without access to the technology itself. In this paper, we investigate the economy of the SIGMA plants, and the implications of this technology on the Uranium Global Market. (authors)

  12. SIGMA, the novel approach of a new non-proliferating uranium enrichment technology

    International Nuclear Information System (INIS)

    Rivarola, M.; Florido, P.; Brasnarof, D.; Bergallo, J.

    2001-01-01

    The SIGMA concept, under development by Argentina, represents the evolution of the Uranium Enrichment Gaseous Diffusion technology, updated to face the challenge of the new economic-based and competitive world frame. The Enrichment technology has been historically considered as a highly proliferating activity in the nuclear field, and central countries have limited the access of the developing countries to this technology. The SIGMA concept incorporates innovative proliferation resistant criteria at the beginning of the design process, and inherits all the non-proliferation features of the Gaseous Diffusion Plants (GDPs). The radical new proliferation resistant approach of the SIGMA technology, suggest a new kind of global control of the Uranium Enrichment Market, were some developing countries might access to an Enrichment plant without accessing to the technology itself. In this paper, we analyse the economy of the SIGMA plants, and the implications of this technology on the Uranium Global Market. (authors)

  13. Cavity pressure/residual stress measurements from the Non-Proliferation Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Heinle, R.A.; Hudson, B.C. [Lawrence Livermore National Lab., CA (United States); Hatch, M.A. Jr.

    1994-12-31

    The Lawrence Livermore National Laboratory planned and conducted experiments on the Non-Proliferation Experiment to determine post-detonation gas pressure inside the explosive cavity and the residual rock stress in the region immediately outside the cavity. Before detonation there was significant concern that steam and detonation products would create very high temperatures and pressure in the blast cavity that would exist for weeks and months after firing. This could constitute a safety hazard to personnel re-entering the tunnel. Consequently the Lawrence Livermore National Laboratory was asked to field its Cavity Pressure/Residual stress monitor system on the Non-Proliferation Experiment. We obtained experimental data for the first 600 ms after the explosion and again several weeks after detonation upon tunnel re-entry. We recorded early-time cavity pressure of about 8.3 MPa. In addition we believe that the ends of our sensor hoses were subjected to an ambient driving pressure of about 0.5 MPa (absolute) that persisted until at least three weeks after zero time.

  14. Statement at Inauguration Ceremony for Vienna Center for Disarmament and Non-Proliferation, 25 February 2011, Vienna, Austria

    International Nuclear Information System (INIS)

    Amano, Y.

    2011-01-01

    I was a member of the Group of Governmental Experts which drafted the United Nations Study on Disarmament and Non proliferation Education in 2002. In my new role at the IAEA, I continue to attach great importance to education. I believe it is vital that we educate the people of the world about how devastating nuclear weapons are and build awareness of the importance of nuclear disarmament and non-proliferation. I have no doubt that the new Vienna Center for Disarmament and Non-Proliferation will make an important contribution in this area. The recent conclusion of the new START Treaty between the Russian Federation and the United States was a welcome development in the nuclear disarmament field. Reducing the role and numbers of nuclear weapons is a positive step towards a safe and peaceful world free of nuclear weapons which can impact positively on nuclear non-proliferation efforts. But, of course, further steps are needed. Disarmament and non-proliferation education have an essential role to play in maintaining and strengthening the momentum towards achieving a world free of nuclear weapons. The IAEA has for decades been actively involved in promoting nuclear non-proliferation education. My colleagues and I speak about nuclear non-proliferation throughout the world. We organize briefings here in Vienna for members of parliament, government officials, think tanks, academics and other groups. We host educational seminars for NGOs, diplomats and journalists on the Agency's non-proliferation activities - the latest one was held this week. The IAEA also provides opportunities for on-the-job training and work experience to students and young professionals. Indeed, several Monterey Institute graduates are currently working with us. This is an excellent example of how disarmament and non-proliferation education can contribute to promoting international peace and security. The 9/11 terrorist attacks in the United States took place during my time with Monterey in

  15. Da hiperglobalização à proliferação de regimes normativos From globalization to the proliferation of normative regimes

    Directory of Open Access Journals (Sweden)

    Roberto Chacon de Albuquerque

    2009-12-01

    Full Text Available Este artigo analisa o conflito entre duas propostas para a solução da crise financeira internacional que representam tradições econômicas e políticas distintas, a anglo-americana e a franco-alemã. Washington e Londres propõem sanar os efeitos da crise internacional, enquanto berlim e paris sugerem uma nova arquitetura para o mercado financeiro, com uma autoridade internacional centralizada para regulá-lo e controlá-lo, com cessão de soberania. estas duas propostas contrapuseram-se na última reunião do g-20 ocorrida em Londres. Mais de setenta anos atrás, a conferência econômica de londres, iniciada em 12 de junho de 1933, teve como objetivo adotar medidas contra a grande depressão, estimulando o comércio internacional e estabilizando o mercado de câmbio. a recusa a uma autoridade central para regular e controlar o mercado financeiro favorece a proliferação de regimes normativos.This article analyzes the conflict between two proposals aiming at solving the international financial crisis that represent different economic and political traditions, the anglo-american and the franco-german ones. Washington and London propose to repair the effects of the international crisis, while berlin and paris suggest a new architecture for the financial market, with a central authority in charge of regulating and controlling it, with cession of sovereignty. These two proposals have been confronted at the last g-20 meeting that took place in London. More than seventy years ago, the London economic conference, which began on 12 june 1933, had as goal the adoption of measures against the great depression, by stimulating the international trade and stabilizing the foreign exchange market. The refusal to a central authority in charge of regulating and controlling the financial market favors the proliferation of normative regimes.

  16. Sweden and the making of nuclear non-proliferation: from indecision to assertiveness

    International Nuclear Information System (INIS)

    Dassen, L. van

    1998-03-01

    Swedish research on nuclear weapons started at a modest scale in 1945 but was soon expanded. By the early 1950s the research programme started to face some of the problems that were going to accompany it for the rest of its life: different priorities and cost-estimates were made by the sectors that wanted to develop nuclear energy and those working on the bomb. Moreover, an introduction of nuclear weapons would lead to a major redistribution of resources to the disadvantage of the navy and army. The public and political debates intensified during the 1950s and culminated in 1960. At first, pro-nuclear voices had been strongest but were soon challenged by interest groups, unions and peace movements. 1960, a committee within the government had established a compromise: Nuclear weapons research for production of weapons would be terminated, while research on the consequences of nuclear weapons would continue. It was a cosmetic decision that could cover for a continued research on weapons design. Nevertheless, there are some general qualities from the debates that indicate why the outcome was that Sweden signed the NPT in 1968. First, the number of interested persons, groups movements and party politicians engaged in the issue increased every time the issue came up. Secondly, the segments of society that supported the nuclear option remained roughly the same. No strong movements rallied to the defence of this position. On the other hand, the anti-nuclear wing received more and more followers. Third, there was a marked tendency by virtually all actors (except the military) to include every sign of progress in international disarmament and non-proliferation efforts as arguments against Swedish proliferation. Since 1968, the non-proliferation choice has ben manifested through Sweden''s adherence to the NPT and this has been accompanied by a strong commitment to other non-proliferation initiatives

  17. Sweden and the making of nuclear non-proliferation: from indecision to assertiveness

    Energy Technology Data Exchange (ETDEWEB)

    Dassen, L. van [Uppsala Univ. (Sweden). Dept. of Peace and Conflict Research

    1998-03-01

    Swedish research on nuclear weapons started at a modest scale in 1945 but was soon expanded. By the early 1950s the research programme started to face some of the problems that were going to accompany it for the rest of its life: different priorities and cost-estimates were made by the sectors that wanted to develop nuclear energy and those working on the bomb. Moreover, an introduction of nuclear weapons would lead to a major redistribution of resources to the disadvantage of the navy and army. The public and political debates intensified during the 1950s and culminated in 1960. At first, pro-nuclear voices had been strongest but were soon challenged by interest groups, unions and peace movements. 1960, a committee within the government had established a compromise: Nuclear weapons research for production of weapons would be terminated, while research on the consequences of nuclear weapons would continue. It was a cosmetic decision that could cover for a continued research on weapons design. Nevertheless, there are some general qualities from the debates that indicate why the outcome was that Sweden signed the NPT in 1968. First, the number of interested persons, groups movements and party politicians engaged in the issue increased every time the issue came up. Secondly, the segments of society that supported the nuclear option remained roughly the same. No strong movements rallied to the defence of this position. On the other hand, the anti-nuclear wing received more and more followers. Third, there was a marked tendency by virtually all actors (except the military) to include every sign of progress in international disarmament and non-proliferation efforts as arguments against Swedish proliferation. Since 1968, the non-proliferation choice has ben manifested through Sweden``s adherence to the NPT and this has been accompanied by a strong commitment to other non-proliferation initiatives. Refs.

  18. Nuclear disarmament and non-proliferation in Northeast Asia

    International Nuclear Information System (INIS)

    Han Yong-Sup

    1995-01-01

    This paper attempted to find out ways to facilitate bilateral and regional arms control regarding nuclear issues in Northeast Asia. This is done in order to reduce uncertainties regarding nuclear policy and capabilities of those countries, and thus to enhance transparency and confidence in the region. In order to bring them into the nuclear disarmament and non-proliferation process in an effective way, we revisited the issues that contributed to the acceleration of the arms race. The review provided insights into the future course of China, the two Koreas and Japan regarding their nuclear policy and capabilities. The findings of this study indicate a general likelihood of resistance to outside request for arms control and disarmament in the countries in Northeast Asia. Besides their continuation with the conventional arms race, countries in Northeast Asia are reluctant to go ahead with the programmes to enhance transparency, build confidence in the region, and to forgo intentions to go nuclear. China is slowly but steadily increasing its nuclear arsenals. Its nuclear arms control policy is not well integrated with nuclear policy and strategy, and it is subject to the overarching goal of nuclear policy and strategy to advance China's status and national security interests in the international community. Thus, it will be very difficult for other countries to bring China to the arms control process for the time being. North Korea has intended to develop nuclear weapons in order to hedge against uncertainties. This poses a threat to the NPT regime and the peace and security of Northeast Asia. Clearly, North Korea has shown its reluctance to disclose the entirety of its nuclear programme under the IAEA inspections. Although South Korea has taken a bold initiative to forgo uranium enrichment and reprocessing capabilities, it has still not fully paid off. Japan adds the problem of plutonium surplus to the uncertain security environments surrounding Northeast Asia

  19. Nuclear disarmament. Options for the coming non-proliferation treaty surveillance cycle; Nukleare Abruestung. Optionen fuer den kommenden Ueberpruefungszyklus des NVV

    Energy Technology Data Exchange (ETDEWEB)

    Mueller, Harald

    2011-07-01

    The report is aimed on the nuclear disarmament discussion with respect to the disagreement of nuclear weapon states and those without nuclear weapons, esp. the non-aligned movement (NAM) concerning the non-proliferation treaty. The report covers the following issues: The role of the non-proliferation treaty, nuclear disarmament in the last surveillance conference 2010, the different disarmament philosophies, the possibilities of bridging the disagreement, further disarmament options for the future non-proliferation treaty surveillance cycle, German options for the future surveillance cycle.

  20. The impact of non-proliferation policies on the uranium market - an industry view

    International Nuclear Information System (INIS)

    Stephany, M.

    1977-01-01

    It is concluded that from an economic point of view, the impact of the present political discussions on non-proliferation (referring particularly to U.S. and Canadian initiatives) on the uranium market (through the choice of reactor programmes in different countries, and other parts of the fuel cycle, such an enrichment, reprocessing, the use of plutonium and the disposal of radioactive waste) cannot be assessed quantitatively. It is believed, however, that in general terms the non-proliferation issue will lead to an increase in the cost of nuclear energy and of all energy. It is also considered that it will tend to strengthen nationalism and thereby to restrict international trade. (U.K.)

  1. Considerations on nonproliferation regime meeting in a changing world

    International Nuclear Information System (INIS)

    Kurihara, Hiroyoshi; Kikuchi, Masahiro

    1994-01-01

    This paper summarizes the past history of worldwide nonproliferation regime, then proposes the future improvements on the regime. Present worldwide nonproliferation regime have been formulated during the cold war era. Therefore, the structure and measures of the regime were heavily influenced by the features of cold war era. Though the cold war was over, still new international order does not seem to be on the horizon, we need to review the present regime and to improve the regime compatible to new world situation. Generally speaking, the nonproliferation regime have gained moderate success so far. We could point out the following features as a kind of success: 1) No increase of overt Nuclear Weapon State (NWS), 2) All five NWSs have finally participated to the NPT, 3) South Africa has destroyed its nuclear weapons and became Non-Nuclear Weapon State (NNWS), 4) Successful conclusions of some regional arrangements, such as Tlatelolco, Ralotonga, and 5) Strengthening of export control on sensitive items. On the other hand, we recognize the following points as the failures of the regime. 6) India, Pakistan and Israel reject to join the NPT, 7) Existence of some violation against NPT regime, i.e. Iraqi case and DPRK case, 8) Insufficient effective measures against brain drain problem, 9) Risk exists for the long term extension of NPT, and 10) Insufficient flexibility to meet changing boundary conditions. We would propose the various measures for strengthening to meet changing boundary conditions, as follows: 11) Measures to be taken along with future civil use of Plutonium, 12) Strengthening and rationalizing international safeguards, 13) Countermeasures for emerging new types of nuclear proliferation, 14) Strengthening nuclear material control in NWS, 15) Measures to be taken for nuclear material from dismantled nuclear weapons, and 16) Nuclear disarmament. (author)

  2. Need for Strengthening Nuclear Non-Proliferation and Safeguards Education to Prepare the Next Generation of Experts

    International Nuclear Information System (INIS)

    Janssens, W.A.M.; Peerani, P.; ); Gariazzo, C.; Ward, S.; Crete, J.-M.; Braunegger-Guelich, A.

    2015-01-01

    Although nuclear non-proliferation and safeguards are a continuous concern of the international community and discussed frequently at international fora and conferences, the academic world is not really on board with these topics. What we mean by this is that nuclear non-proliferation and safeguards is only very seldom part of a university curriculum. In the few cases where it does appear in the curriculum, whether in a nuclear engineering course or a political sciences master programme, it is typically covered only partially. Nuclear non-proliferation and safeguards are multidisciplinary and embrace, inter alia, historical, legal, technical, and political aspects. This is perhaps the reason why it is challenging for a single professor or university to develop and implement a comprehensive academic course or programme in this area. Professional organizations in this field, like the European Safeguards Research and Development Association (ESARDA) and the Institute for Nuclear Materials Management (INMM), have made first steps to address this issue by implementing specific educational activities. However, much more needs to be done. Therefore, ESARDA, INMM and the International Atomic Energy Agency (IAEA) are in the process of joining efforts to identify key elements and priorities to support universities in establishing appropriate and effective academic programmes in this area. This paper will share best practices, achievements and lessons learned by ESARDA, INMM and the IAEA in providing education and training to develop and maintain the expertise of nuclear non-proliferation and safeguards professionals. In addition, it will suggest potential ways on how to assist universities to get prepared for building-up the next generation of experts able to meet any future challenges in the area of non-proliferation and safeguards. (author)

  3. Impasses and mistakes of the nuclear non-proliferation policy

    International Nuclear Information System (INIS)

    Hirst, M.

    1980-01-01

    It is analyzed the limitations for implementing the American Nuclear non-proliferation policy. It is shown the crisis of the North American international relations, with the economic and scientific development of the advanced capitalist nations and some countries of the third world, the penetration of these countries in the world trade commerce of the nuclear industry as sellers and cunsumers, and the Latin American's and Brazil's position in the international panorama of nuclear power. (M.C.K.) [pt

  4. Assembling an experimentalist regime: transnational governance interactions in the forest sector

    NARCIS (Netherlands)

    Overdevest, C.; Zeitlin, J.

    2014-01-01

    Transnational governance initiatives increasingly face the problem of regime complexity in which a proliferation of regulatory schemes operate in the same policy domain, supported by varying combinations of public and private actors. The literature suggests that such regime complexity can lead to

  5. The Asia-Pacific region: non-proliferation and other disarmament issues

    International Nuclear Information System (INIS)

    1992-01-01

    In the past few years, the United States and the former Soviet Union began to adjust their force structures in Asia-Pacific region. In this respect, a large range of issues have been raised in discussions on the non-proliferation of nuclear and other weapons of mass destruction. Apart from the issues and trends related to proliferation, military expenditure, arms transfer and other disarmament matters, the specific situations in the respective subregions of South-East Asia, South Asia and North-East Asia were discussed. Comprehensive and verified commitments not to possess any such weapons is stressed as the main goal of the meeting. It is vitally important that opportunities that were opened should be seized to prevent the spread of nuclear, chemical, biological as well as highly destabilizing conventional weapons

  6. Unified flow regime predictions at earth gravity and microgravity

    International Nuclear Information System (INIS)

    Crowley, C.J.

    1990-01-01

    This paper illustrates the mechanistic models developed to predict flow regime transitions at earth gravity for various pipe inclinations can be successfully applied to existing microgravity flow regime data from several experiments. There is a tendency in the literature for flow regime comparisons in several inclination ranges and at various gravity (acceleration) levels to be treated by separate models, resulting in a proliferation of models for the prediction of flow regimes. One set of mechanistic models can be used to model the transitions between stratified, slug, bubbly, and annular flow regimes in pipes for all acceleration vectors and magnitudes from earth gravity to microgravity

  7. Non-Proliferation, the IAEA Safeguards System, and the importance of nuclear material measurements

    Energy Technology Data Exchange (ETDEWEB)

    Stevens, Rebecca S. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-09-18

    The objective of this project is to explain the contribution of nuclear material measurements to the system of international verification of State declarations and the non-proliferation of nuclear weapons.

  8. The Nuclear Progress And The Non-Proliferation Policies

    Energy Technology Data Exchange (ETDEWEB)

    Popa-Simil, Liviu [Los Alamos, NM 87544 (United States)

    2009-06-15

    The 2008 fall crisis showed the limits of globalization under the actual rules and de-regulations promoted by few developed countries. It also showed the weakness of the planetary economy induced by strong economic connections that makes the propagation of crises faster than the spread of welfare. The increase in severe weather and natural disasters showed how fast the civilization can be spoiled while the competition for oil resources made the interstate tensions grow. For almost all states, the development of the nuclear power becomes a prime option, even oil producers started to show interest in nuclear technology and also, policies that in particular are clearly oriented towards national development policies. The fact that anybody mastering nuclear technologies and uses for power production is capable in a reasonable time to produce weapons is a well-known fact. Therefore, in order to reduce the proliferation risk it is necessary to contain the nuclear science development. An alternative is to shift the weight in promoting renewable energies, as potential future energy alternative. Considering rigorously the future climate change effects, it becomes obvious that any delay in nuclear development will turn very costly for any nation ignoring all these facts and, the complexity of the real nonproliferation is growing. This new trend raises serious challenges in front of all states regarding the non-proliferation and, in order to keep control and stimulate a sound nuclear development, some of the actual non-proliferation concepts and policies have to be reformulated and enhanced. This has to be done in parallel with a more intensive implication of the international organisms in the real development of the nuclear power at national level. The large diversity of nuclear applications with huge collateral implication in every national economy makes the role of the international organisms orders of magnitude more important. The new challenges posed in front of the

  9. The Non-Proliferation Treaty on the threshold to the 21st century

    International Nuclear Information System (INIS)

    Fischer, W.

    1991-06-01

    The basic outlines of non-proliferation policy, its instruments, the position of the protagonists' interests and the fundamental fields of conflict are to the fore. The history and structure of international non-poliferation policy and, in particular, of the NPT, are described, the instruments for verifying the purely peaceful use of nuclear power (safeguards) are analysed, and important future technological and political challenges of the Treaty are listed. (orig./HP) [de

  10. [Effects of non-saccharomyces albicans metabolic products on the proliferation of human umbilical vein endothelial cell ECV304].

    Science.gov (United States)

    Chen, Bin; Che, Tuanjie; Bai, Decheng; He, Xiangyi

    2013-04-01

    To evaluate the effects of non-Saccharomyces albicans metabolic products on the cell cycle distribution and proliferation of human umbilical vein endothelial cell ECV304 cells in vitro. The parallel dilution supernatant of Saccharomyces tropicalis, Saccharomyces krusei and Saccharomyces glabrata were prepared, and 1, 4, 16-fold(s) diluted concentration and control group were set up. The line of human umbilical vein endothelial cell ECV304 was cultured in vitro and treated by non-Saccharomyces albicans supernatant. The proliferous effect of ECV304 induced by non-Saccharomyces albicans supernatant after 24, 48, 72 h was detected by the methods of MTT, and the changes of cell density and cycle after 48 h were investigated by inverted microscope and flow cytometry. At the 24th hour, all of the higher concentration (1-fold) of non-Saccharomyces albicans supernatant and the 4-folds diluted Saccharomyces krusei could promote ECV304 proliferation(P Saccharomyces albicans supernatant at 48h and 72th hour, Saccharomyces krusei supernatant and Saccharomyces glabrata supernatant significantly increased proliferation rate of ECV304, while Saccharomyces tropicalis supernatant group showed no significant change no matter which concentration was tested. At 48th hour after adding the non-Saccharomyces albicans supernatant, the ECV304 cells density treated by Saccharomyces krusei supernatant and Saccharomyces glabrata supernatant were significantly higher under the inverted microscope. The G0/G1 population of ECV304 cells decreased while cell proliferation index (PI) increased after incubated with Saccharomyces krusei supernatant and Saccharomyces glabrata supernatant for 48 hours (P Saccharomyces tropicalis group showed no significant change (P > 0.05). The metabolic products of Sacharoymces krusei and Saccharomyces glabrata could induce proliferation of ECV304 cell, which suggests non-Saccharomyces albicans should be undergone more attention clinically in detection and treatment.

  11. Economic and Non-proliferation Policy Considerations of Uranium Enrichment in Brazil and Argentina

    International Nuclear Information System (INIS)

    Short, Steven M.; Phillips, Jon R.; Weimar, Mark R.; Mahy, Heidi A.

    2008-01-01

    The nuclear development programs of both Argentina and Brazil have, since the 1970s, been premised on the desire for self-sufficiency and assurance of nuclear fuel supply. While military rivalry and mutual distrust led to nuclear weapons related development programs in the 1970s and 1980s, both countries have since terminated these programs. Furthermore, the governments of both countries have pledged their commitment to exclusively non-explosive use of nuclear energy and have signed the Non Proliferation Treaty (NPT). Utilizing rights provided for under the NPT, both Argentina and Brazil have nuclear fuel production facilities, with the notable exception of enrichment plants, that provide much of the current indigenous fuel requirements for their nuclear power plants. However, both countries are actively developing enrichment capability to fill this gap. The purpose of this report is to assess the economic basis and non-proliferation policy considerations for indigenous enrichment capability within the context of their desired self-sufficiency and to evaluate possible United States Government policy options.

  12. Economic and Non-proliferation Policy Considerations of Uranium Enrichment in Brazil and Argentina

    Energy Technology Data Exchange (ETDEWEB)

    Short, Steven M.; Phillips, Jon R.; Weimar, Mark R.; Mahy, Heidi A.

    2008-09-01

    The nuclear development programs of both Argentina and Brazil have, since the 1970s, been premised on the desire for self-sufficiency and assurance of nuclear fuel supply. While military rivalry and mutual distrust led to nuclear weapons related development programs in the 1970s and 1980s, both countries have since terminated these programs. Furthermore, the governments of both countries have pledged their commitment to exclusively non-explosive use of nuclear energy and have signed the Non Proliferation Treaty (NPT). Utilizing rights provided for under the NPT, both Argentina and Brazil have nuclear fuel production facilities, with the notable exception of enrichment plants, that provide much of the current indigenous fuel requirements for their nuclear power plants. However, both countries are actively developing enrichment capability to fill this gap. The purpose of this report is to assess the economic basis and non-proliferation policy considerations for indigenous enrichment capability within the context of their desired self-sufficiency and to evaluate possible United States Government policy options.

  13. Nuclear Safeguards and Non-Proliferation Education at Texas A&M University

    International Nuclear Information System (INIS)

    Gariazzo, C.; Charlton, W.

    2015-01-01

    The MS degree in Nuclear Engineering - Non-proliferation at Texas A&M University is administered by the Nuclear Security Science and Policy Institute (NSSPI). The oldest and largest of its kind in the US, 45 M.S. and 15 Ph.D. students conducted technical research in relevant areas: safeguards, nuclear security, non-proliferation, and arms control. In addition to focusing on graduate education with a wide combination of internationally-recognized talent, NSSPI faculty lead research and service activities in safeguarding of nuclear materials and reducing nuclear threats. Texas A&M Nuclear Engineering students take relevant nonproliferation and safeguards courses (within the College of Engineering and the Texas A&M Bush School of Government) as well as conduct their research under competent experts. The complete educational experience here is unique because of the strong research and educational support NSSPI provides. This paper will detail these endeavors and convey contributions from NSSPI for developing next-generation safeguards experts via practical experiences and strong affiliations with real-world practitioners. The safeguards and non-proliferation education programme blends historical, legal, technical and policy aspects that is unique for a technical university such as Texas A&M. Beyond classroom lectures, NSSPI provides opportunities for students ranging from asynchronous learning modules to practical experiences. Publicly-available self-paced, online course modules in basic and advanced safeguards education have been developed by NSSPI as supplemental nuclear education for students and professionals. By leveraging NSSPI's contacts, students participate in exchange programmes with international institutions as well as partake in experiences like engaging safeguards practitioners at nuclear fuel cycle facilities around the world, conducting experiments at internationally-renowned laboratories, and representing their communities at workshops worldwide

  14. Open Source and Trade Data for Non-Proliferation: Challenges and Opportunities

    International Nuclear Information System (INIS)

    Stewart, I.; Gillard, N.

    2015-01-01

    This paper explores what more systematic exploitation of trade data can contribute to the state evaluation process. The paper begins by setting out a typology of trade data, which groups the data into five categories: · Government Declared Data, which is prepared and submitted by States to an international authority for non-proliferation purposes. · Government Recorded Data, which includes information collected by the state for its own purposes, and which is not routinely submitted to international authorities for non-proliferation purposes. It includes (some) export licencing data, customs data, and business registration information. · Business-held data, which includes information on a company's own products and customers, but also ''market intelligence''. · Intelligence and Enforcement Derived Information, which can include information on specific procurement attempts, networks, or procurement requirements. · Procurement Requirements Information, which can include information released by a programme for the purpose of seeking goods or services. Challenges and opportunities related to further exploitation of trade data sources in each category are then explored, as are factors related to accessibility (both in terms of mandates and more practical considerations), reliability (including presentation of a typology), completeness, and duplication in data. Next, the paper explores how the IAEA can systematically collect, integrate and analyze the various sources of trade data given the considerations outlined above. In particular, this section focuses on how data in variable structures can be integrated into the state evaluation process. In concluding, the paper will describe how the newly formed ''Collaboration on Open Source and Trade Analysis for Non-proliferation'' (COSTA-NP) is seeking to develop each of the categories of trade data. The paper links to research objectives 1.3, 1.4, 2.1, 2.3, and 2.4 of the IAEA

  15. The role of nuclear suppliers group in preventing the proliferation of nuclear weapons

    International Nuclear Information System (INIS)

    Medakovic, S.; Cizmek, A.; Horvatic, M.; Ilijas, B.

    2009-01-01

    The non-proliferation regime today is a pretty heterogeneous system of measures and different ways of control of nuclear material production, transport and use, as well as nuclear activities and technology in general. In its basis are the Statute of International Atomic Energy Agency (IAEA) and Non-proliferation Treaty. However, the development of a nuclear technology and technological progress in the world in general, poses the need for more efficient and much more concrete systems of control of nuclear material and activities. One of organizations which cover these issues is Nuclear Suppliers Group (NSG), founded in 1991 with goal to assemble all states suppliers, regardless are they signatories of Non-proliferation Treaty or not. The important thing is that NSG do not rely only to the list of limitations for traffic of the equipment which is directly related to nuclear activities, but also to so call dual use equipment, i.e. equipment which could be, besides its primary purpose, converted to some nuclear activities. Concerning continuous technological development, and also the actual political situation in the world, these lists are continuously amended. In this presentation the principles and methods of work of NSG are analyzed, together with the role of the Republic of Croatia as its member.(author)

  16. The Role of Nuclear Suppliers Group in Preventing the Proliferation of Nuclear Weapons

    International Nuclear Information System (INIS)

    Ilijas, B.; Cizmek, A.; Prah, M.; Medakovic, S.

    2008-01-01

    The non-proliferation regime today is a pretty heterogeneous system of measures and different ways of control of nuclear material production, transport and use, as well as nuclear activities and technology in general. In its basis are the Statute of International Atomic Energy Agency (IAEA) and Non-proliferation Treaty. However, the development of a nuclear technology and technological progress in the world in general, poses the need for more efficient and much more concrete systems of control of nuclear material and activities. One of organizations which covers these issues is Nuclear Suppliers Group (NSG), founded in 1991 with goal to assemble all states suppliers, regardless are they signatories of Non-proliferation Treaty or not. The important thing is that NSG do not rely only to the list of limitations for traffic of the equipment which is directly related to nuclear activities, but also to so call dual use equipment, i.e. equipment which could be, besides its primary purpose, converted to some nuclear activities. Concerning continuous technological development, and also the actual political situation in the world, these lists are continuously amended. In this presentation the principles and methods of work of NSG are analyzed, together with the role of the Republic of Croatia as its member as from 2005.(author)

  17. Security environment and nuclear proliferation problems in East Asia

    International Nuclear Information System (INIS)

    Suh, Mark Byung-Moon

    1997-01-01

    East Asia was and still is divided into two conflicting ideological blocs. Because of the Cold War between these two blocs, two international wars were fought and tensions limited interactions among these countries. Despite these political constraints, in recent years East Asia has become economically one of the most dynamic regions in the world. Now that the Cold War between the USA and the Soviet Union is over, the danger of global nuclear war involving the nuclear powers in the region has been practically eliminated. Nonetheless, security has become more complex and demands a whole new set of arrangements. Yet the region lacks a cohesive multilateral framework for conflict resolution, and only recently have various attempts been made to create a political forum for the countries in the region. The problem and the danger of nuclear proliferation was vividly shown by the North Korean nuclear crisis in the last years. This issue not only halted the fragile process of normalization between the two Koreas, which started in 1988, but almost led to a new military conflict on the peninsula involving the two Koreas and the USA. It was defused only after the USA proved willing to offer security guarantees to North Korea. This problem still needs to be resolved, and it demands radical changes in the overall political environment in the region. Needless to say, proliferation in North Korea would have entailed grave consequences for the security of the region as well as for the international non-proliferation regime. This paper reviews the issue of nuclear proliferation of the three non-nuclear states in the region and deals with the non-introduction of nuclear weapons in the region by the nuclear powers. It discusses the prospects for a nuclear-weapon-free zone on the Korean peninsula. Perspectives of a sustainable security environment in East Asia will be briefly discussed

  18. Review of international forum on peaceful use of nuclear energy and nuclear non-proliferation

    International Nuclear Information System (INIS)

    Shimizu, Ryo; Suzuki, Mitsutoshi; Sakurai, Satoshi; Tamai, Hiroshi; Yamamura, Tsukasa; Kuno, Yusuke

    2012-02-01

    International forum on peaceful use of nuclear energy and nuclear non-proliferation was held at Gakushi-kaikan, Tokyo on February 2-3, 2011 in cooperation with The Japan Institute of International Affairs (JIIA) and The University of Tokyo Global COE. In our International Forum, we would like to encourage active discussion of international challenges to and solutions for compatibility between peaceful use of nuclear energy and nuclear non-proliferation, and international cooperation for emerging nuclear energy states. It was successfully carried out with as many as 310 participants and a lot of discussions. This report includes abstracts of keynote speeches, summary of panel discussions and materials of the presentations in the forum. (author)

  19. Assembling an experimentalist regime: transnational governance interactions in the forest sector revisited

    NARCIS (Netherlands)

    Overdevest, C.; Zeitlin, J.; Bruszt, L.; McDermott, G.A.

    2014-01-01

    Transnational governance initiatives increasingly face the problem of regime complexity in which a proliferation of regulatory schemes operate in the same policy domain, supported by varying combinations of public and private actors. The literature suggests that such regime complexity can lead to

  20. Cell Adhesion and Proliferation on Sulfonated and Non-Modified Chitosan Films.

    Science.gov (United States)

    Martínez-Campos, Enrique; Civantos, Ana; Redondo, Juan Alfonso; Guzmán, Rodrigo; Pérez-Perrino, Mónica; Gallardo, Alberto; Ramos, Viviana; Aranaz, Inmaculada

    2017-05-01

    Three types of chitosan-based films have been prepared and evaluated: a non-modified chitosan film bearing cationizable aliphatic amines and two films made of N-sulfopropyl chitosan derivatives bearing both aliphatic amines and negative sulfonate groups at different ratios. Cell adhesion and proliferation on chitosan films of C2C12 pre-myoblastic cells and B16 cells as tumoral model have been tested. A differential cell behavior has been observed on chitosan films due to their different surface modification. B16 cells have shown lower vinculin expression when cultured on sulfonated chitosan films. This study shows how the interaction among cells and material surface can be modulated by physicochemical characteristics of the biomaterial surface, altering tumoral cell adhesion and proliferation processes.

  1. INFCE and US non-proliferation policy

    Energy Technology Data Exchange (ETDEWEB)

    Donnelly, W H

    1980-12-01

    The International Fuel Cycle Evaluation (INFCE), which published its final reports in February 1980 produced a massive international effort of a kind never before seen. Over a period of two years its eight working groups held 61 meetings involving 519 experts from 46 countries and five international organizations. Here the author outlines the background and structure of INFCE and discusses how its recommendations diverge from US nonproliferation policy. If the future of nuclear power is to include more sensitive facilities in which plutonium and highly enriched uranium are present, it must be determined whether the risks seen in proliferation are great enough to cause the USA and other governments to place such facilities under some form of international ownership or control in addition to international safeguards. A final crucial problem is deciding what can and should be done to dissuade non-nuclear-weapons states from the direct manufacture of nuclear weapons. 6 references.

  2. The SSAC in international safeguards and non-proliferation aspects

    International Nuclear Information System (INIS)

    Bett, F.L.; Humphreys, J.J.

    1989-01-01

    The history of international efforts against horizontal proliferation, including the Baruch Plan, bilateral safeguards agreement, IAEA safeguards, the Nuclear Non-Proliferation Treaty, the Zangger Committee, the Nuclear Supplier Group guidelines and the Physical Protection Convention, is reviewed. The role of IAEA NPT safeguards in verifying nondiversion and ensuring no misuse of supplied nuclear items is discussed. The vital importance of successful performance of this role to peaceful nuclear commerce is stressed. The application of NPT safeguards by the IAEA is described, particularly the IAEA's requirement that a State System of Accounting for and Control of Nuclear Material be established. Such a State System has two different but complementary areas of responsibility - ensuring that the use of nuclear material is controlled effectively and can be readily accounted for (this includes the area of physical protection), and providing accounts of nuclear material to responsible bodies such as the State's government and equally importantly to the IAEA for safeguards purpose, as the IAEA bases its conclusions about diversion on its verification of the data provided by the State System

  3. Quantum fields in the non-perturbative regime. Yang-Mills theory and gravity

    International Nuclear Information System (INIS)

    Eichhorn, Astrid

    2011-01-01

    In this thesis we study candidates for fundamental quantum field theories, namely non-Abelian gauge theories and asymptotically safe quantum gravity. Whereas the first ones have a stronglyinteracting low-energy limit, the second one enters a non-perturbative regime at high energies. Thus, we apply a tool suited to the study of quantum field theories beyond the perturbative regime, namely the Functional Renormalisation Group. In a first part, we concentrate on the physical properties of non-Abelian gauge theories at low energies. Focussing on the vacuum properties of the theory, we present an evaluation of the full effective potential for the field strength invariant F μν F μν from non-perturbative gauge correlation functions and find a non-trivial minimum corresponding to the existence of a dimension four gluon condensate in the vacuum. We also relate the infrared asymptotic form of the β function of the running background-gauge coupling to the asymptotic behavior of Landau-gauge gluon and ghost propagators and derive an upper bound on their scaling exponents. We then consider the theory at finite temperature and study the nature of the confinement phase transition in d = 3+1 dimensions in various non-Abelian gauge theories. For SU(N) with N= 3,..,12 and Sp(2) we find a first-order phase transition in agreement with general expectations. Moreover our study suggests that the phase transition in E(7) Yang-Mills theory also is of first order. Our studies shed light on the question which property of a gauge group determines the order of the phase transition. In a second part we consider asymptotically safe quantum gravity. Here, we focus on the Faddeev-Popov ghost sector of the theory, to study its properties in the context of an interacting UV regime. We investigate several truncations, which all lend support to the conjecture that gravity may be asymptotically safe. In a first truncation, we study the ghost anomalous dimension which we find to be negative at the

  4. Non-Proliferation Community, Do We Really Speak the Same Language?

    International Nuclear Information System (INIS)

    Chatelus, R.; Janssens, W.A.M.; Michel, Q.; Viski, A.; Sevini, F.; Charatsis, C.; )

    2015-01-01

    The non-proliferation community, with its many different stakeholders, has issues with a number of terms and concepts which have different meanings, not only in different national languages but also for scientists, diplomats, engineers, law enforcement people, IAEA safeguards staff, and many others. The consequences are not only relevant for translators and seminar participants. This confusion of terms may create misunderstandings with legal, diplomatic and operational consequences. A number of terms, used because of their meaning in English are ''false friends'' in other languages, i.e., they are used because they sound close, but their meaning may be different. The nuances may be about the fact that they cover a narrower, broader, or slightly different concept in another national or professional language. The emblematic example is the English word control, written the same way in many languages but with different connotations. Other examples include terms which have a precise legal definition for some communities whereas other stakeholder see it as generic terms (e.g., technology, transit); terms that are not explicit but have different implicit contents related to the context like outreach or declaration; terms which are distinct in one language but translated into one word in others like specially and especially designed; terms which cover different realities for different work communities like counter-proliferation, analysis; terms which are widely used and hardly defined anywhere like dual-use; or terms which refer to a specific legal or moral reference framework which is not always explicated like illegal, legitimate. This paper will explore issues related to some of these terms used in Western languages, and argue the necessity to take into account these sometimes subtle language differences, realizing the difficulties they may create for practitioners of non-proliferation. Improvements might include revising official reference documents

  5. Explosive performance on the non-proliferation experiment

    Energy Technology Data Exchange (ETDEWEB)

    McKown, T.O.

    1994-03-01

    The non-proliferation experiment, originally called the chemical kiloton experiment, was planned and executed by Lawrence Livermore National Laboratory to investigate the seismic yield relationship and distinguishing seismic signals between a nuclear event and a large mass conventional explosion. The Los Alamos National Laboratory planned and conducted experiments to further their studies of the source function for signals observed seismically. Since all investigations were contingent on the performance of the emplaced chemical explosive, an array of diagnostic measurements was fielded in the emplaced explosive. The CORRTEX system was used to investigate the explosive initiation and to determine the detonation velocities in multiple levels and in numerous directions. A description of the CORRTEX experiments fielded, a review of the data obtained and some interpretations of the data are reported.

  6. Non-linear regime shifts in Holocene Asian monsoon variability: potential impacts on cultural change and migratory patterns

    Science.gov (United States)

    Donges, J. F.; Donner, R. V.; Marwan, N.; Breitenbach, S. F. M.; Rehfeld, K.; Kurths, J.

    2015-05-01

    The Asian monsoon system is an important tipping element in Earth's climate with a large impact on human societies in the past and present. In light of the potentially severe impacts of present and future anthropogenic climate change on Asian hydrology, it is vital to understand the forcing mechanisms of past climatic regime shifts in the Asian monsoon domain. Here we use novel recurrence network analysis techniques for detecting episodes with pronounced non-linear changes in Holocene Asian monsoon dynamics recorded in speleothems from caves distributed throughout the major branches of the Asian monsoon system. A newly developed multi-proxy methodology explicitly considers dating uncertainties with the COPRA (COnstructing Proxy Records from Age models) approach and allows for detection of continental-scale regime shifts in the complexity of monsoon dynamics. Several epochs are characterised by non-linear regime shifts in Asian monsoon variability, including the periods around 8.5-7.9, 5.7-5.0, 4.1-3.7, and 3.0-2.4 ka BP. The timing of these regime shifts is consistent with known episodes of Holocene rapid climate change (RCC) and high-latitude Bond events. Additionally, we observe a previously rarely reported non-linear regime shift around 7.3 ka BP, a timing that matches the typical 1.0-1.5 ky return intervals of Bond events. A detailed review of previously suggested links between Holocene climatic changes in the Asian monsoon domain and the archaeological record indicates that, in addition to previously considered longer-term changes in mean monsoon intensity and other climatic parameters, regime shifts in monsoon complexity might have played an important role as drivers of migration, pronounced cultural changes, and the collapse of ancient human societies.

  7. Hysteresis, regime shifts, and non-stationarity in aquifer recharge-storage-discharge systems

    Science.gov (United States)

    Klammler, Harald; Jawitz, James; Annable, Michael; Hatfield, Kirk; Rao, Suresh

    2016-04-01

    Based on physical principles and geological information we develop a parsimonious aquifer model for Silver Springs, one of the largest karst springs in Florida. The model structure is linear and time-invariant with recharge, aquifer head (storage) and spring discharge as dynamic variables at the springshed (landscape) scale. Aquifer recharge is the hydrological driver with trends over a range of time scales from seasonal to multi-decadal. The freshwater-saltwater interaction is considered as a dynamic storage mechanism. Model results and observed time series show that aquifer storage causes significant rate-dependent hysteretic behavior between aquifer recharge and discharge. This leads to variable discharge per unit recharge over time scales up to decades, which may be interpreted as a gradual and cyclic regime shift in the aquifer drainage behavior. Based on field observations, we further amend the aquifer model by assuming vegetation growth in the spring run to be inversely proportional to stream velocity and to hinder stream flow. This simple modification introduces non-linearity into the dynamic system, for which we investigate the occurrence of rate-independent hysteresis and of different possible steady states with respective regime shifts between them. Results may contribute towards explaining observed non-stationary behavior potentially due to hydrological regime shifts (e.g., triggered by gradual, long-term changes in recharge or single extreme events) or long-term hysteresis (e.g., caused by aquifer storage). This improved understanding of the springshed hydrologic response dynamics is fundamental for managing the ecological, economic and social aspects at the landscape scale.

  8. Non-proliferation and nuclear disarmament: speech of the president Obama at Prague

    International Nuclear Information System (INIS)

    Hautecouverture, B.

    2009-01-01

    Introduced by the Prague speech of april 7 2009, the Obama President program towards the non proliferation and the nuclear disarmament was pointed out by its optimism ambition and determination. But a more detailed lecture shows concurrent positions. The author analyzes the political aspects of the President speech. (A.L.B.)

  9. Non-proliferation issues for the disposition of fissile materials using reactor alternatives

    International Nuclear Information System (INIS)

    Jaeger, C.D.; Duggan, R.A.; Tolk, K.M.

    1996-01-01

    The Department of Energy (DOE) is analyzing long-term storage on options for excess weapons-usable fissile materials. A number of the disposition alternatives are being considered which involve the use of reactors. The various reactor alternatives are all very similar and include front-end processes that could convert plutonium to a usable form for fuel fabrication, a MOX fuel fab facility, reactors to bum the MOX fuel and ultimate disposal of spent fuel in some geologic repository. They include existing, partially completed, advanced or evolutionary light water reactors and Canadian deuterium uranium (CANDU) reactors. In addition to the differences in the type of reactors, other variants on these alternatives are being evaluated to include the location and number of the reactors, the location of the mixed oxide (MOX) fabrication facility, the ownership of the facilities (private or government) and the colocation and/or separation of these facilities. All of these alternatives and their variants must be evaluated with respect to non-proliferation resistance. Both domestic and international safeguards support are being provided to DOE's Fissile Materials Disposition Program (FMDP) and includes such areas as physical protection, nuclear materials accountability and material containment and surveillance. This paper will focus on how the non-proliferation objective of reducing security risks and strengthening arms reduction will be accomplished and what some of the nonproliferation issues are for the reactor alternatives. Proliferation risk has been defined in terms of material form, physical environment, and the level of security and safeguards that is applied to the material. Metrics have been developed for each of these factors. The reactor alternatives will be evaluated with respect to these proliferation risk factors at each of the unit process locations in the alternative

  10. Future of US utilities under non-proliferation policy

    International Nuclear Information System (INIS)

    Ladesich, J.N.

    1978-01-01

    The non-proliferation policy, a negative policy that closes the back end of the nuclear fuel cycle, is only a small part of a chaotic energy environment characterized by inaction. The impact of this environment on California utilities has resulted in a virtual moratorium on new facilities at a time when the nuclear option can be shown to be vital. Utilities are experiencing uncertainties in future power generation because alternatives to nuclear energy may not be the best choices. Utilities feel frustrated by the inaction; not by the objectives of the accountability and security proposals. The utilities will continue to support nuclear power and the completion of the fuel cycle in spite of these uncertainties

  11. Stabilization and immobilization of military plutonium: A non-proliferation perspective

    Energy Technology Data Exchange (ETDEWEB)

    Leventhal, P. [Nuclear Control Institute, Washington, DC (United States)

    1996-05-01

    The Nuclear Control Institute welcomes this DOE-sponsored technical workshop on stabilization and immobilization of weapons plutonium (W Pu) because of the significant contribution it can make toward the ultimate non-proliferation objective of eliminating weapons-usable nuclear material, plutonium and highly enriched uranium (HEU), from world commerce. The risk of theft or diversion of these materials warrants concern, as only a few kilograms in the hands of terrorists or threshold states would give them the capability to build nuclear weapons. Military plutonium disposition questions cannot be addressed in isolation from civilian plutonium issues. The National Academy of Sciences has urged that {open_quotes}further steps should be taken to reduce the proliferation risks posed by all of the world`s plutonium stocks, military and civilian, separated and unseparated...{close_quotes}. This report discusses vitrification and a mixed oxide fuels option, and the effects of disposition choices on civilian plutonium fuel cycles.

  12. Comparison of the effect of activated or non-activated PRP in various concentrations on osteoblast and fibroblast cell line proliferation.

    Science.gov (United States)

    Vahabi, Surena; Yadegari, Zahra; Mohammad-Rahimi, Hossein

    2017-09-01

    Platelet-rich plasma (PRP) contains growth factors which positively affect cell proliferation, cell differentiation, chemotaxis and intracellular matrix synthesis. All these processes are involved in wound healing and tissue regeneration; thus, PRP as a source of growth factors can be used in periodontal regenerative therapies. The purpose of the present study was to assess the effect of various concentrations of activated and non-activated PRP on proliferation of osteoblasts and fibroblasts in vitro. PRP was obtained from three healthy volunteers. 75, 50, 25, and 10% concentrations of f PRP were prepared by dilution in Dulbecco's modified Eagle's medium. In activated PRP groups, PRP concentrations were activated by adding calcium gluconate. Human gingival fibroblast (HGF) cell line and MG-63 (osteosarcoma) human osteoblast-like cell line were used in the study. The MTT proliferation assay was used to assess the effect of different types of PRP concentrates on proliferation of HGF and MG-63 cells, in 24, 48 and 72 h. After 24, 48, and 72 h, the proliferation rate of both cell lines was higher in the positive control group, except in 72 h in HGF cell lines, that 10% non-activated PRP group and 10 and 25% activated PRP groups has higher proliferation rate than the positive control group, which it was not significant. Proliferation rate in cells with 10% activated PRP was highest among samples containing PRP. The current study failed to show the significant effect of activated or non-activated PRP on proliferation of HGFs or MG-63 osteoblast-like cells. However, our results showed that activated PRP had a greater effect than non-activated PRP.

  13. Expression of a novel non-coding mitochondrial RNA in human proliferating cells.

    Science.gov (United States)

    Villegas, Jaime; Burzio, Veronica; Villota, Claudio; Landerer, Eduardo; Martinez, Ronny; Santander, Marcela; Martinez, Rodrigo; Pinto, Rodrigo; Vera, María I; Boccardo, Enrique; Villa, Luisa L; Burzio, Luis O

    2007-01-01

    Previously, we reported the presence in mouse cells of a mitochondrial RNA which contains an inverted repeat (IR) of 121 nucleotides (nt) covalently linked to the 5' end of the mitochondrial 16S RNA (16S mtrRNA). Here, we report the structure of an equivalent transcript of 2374 nt which is over-expressed in human proliferating cells but not in resting cells. The transcript contains a hairpin structure comprising an IR of 815 nt linked to the 5' end of the 16S mtrRNA and forming a long double-stranded structure or stem and a loop of 40 nt. The stem is resistant to RNase A and can be detected and isolated after digestion with the enzyme. This novel transcript is a non-coding RNA (ncRNA) and several evidences suggest that the transcript is synthesized in mitochondria. The expression of this transcript can be induced in resting lymphocytes stimulated with phytohaemagglutinin (PHA). Moreover, aphidicolin treatment of DU145 cells reversibly blocks proliferation and expression of the transcript. If the drug is removed, the cells re-assume proliferation and over-express the ncmtRNA. These results suggest that the expression of the ncmtRNA correlates with the replicative state of the cell and it may play a role in cell proliferation.

  14. Report on the 8. ESARDA course on nuclear safeguards and non-proliferation

    International Nuclear Information System (INIS)

    Grape, S.; Jonter, T.

    2013-01-01

    The 8. ESARDA course on nuclear safeguards and non-proliferation took place in Uppsala, Sweden, on September 12-16, 2011. 44 participants from 15 countries followed the one week long course, comprising four days of lectures, one group exercise and one full day visit to the Swedish final repository (SFR) for short-lived radioactive waste. The lectures covered political and technical aspects related to the general background of safeguards legislation and treaties, the nuclear fuel cycle, destructive and non-destructive safeguards techniques, physical protection, verification technologies such as nuclear material accountancy and control, safeguards inspections, remote monitoring, containment and surveillance, export control, illicit trafficking and nuclear forensics. The course also contained a group exercise, whereby the participants learnt about different nonproliferation treaties on/or related to Weapons of Mass Destruction (WMD): the Chemical Weapons Convention (CWC), the Biological and Toxin Weapons Convention (BWC), the nuclear Non-Proliferation Treaty (NPT) as well as the Comprehensive Nuclear Test Ban Treaty (CTBT) and the Fissile Material Cut-off Treaty (FMCT). The task of the group exercise was to discuss and compare the treaties with respect to obligations and rights of state parties, verification of compliance, membership, terrorism, similarities/differences, successes and failures. The paper is followed by the slides of the presentation

  15. Non-alcoholic beverages, unknown influence on cell proliferation – an [i]in vitro[/i] study

    Directory of Open Access Journals (Sweden)

    Maciej Nowacki

    2014-03-01

    Full Text Available Introduction and objective. The aim of the presented study was to check differences between ‘Diet’ and ‘non-Diet’ soft drinks on cell proliferation. Materials and methods. Coca Cola and Pepsi Cola of different origin and their dietetic versions were examined at concentrations of 2% and 4%. Fructose and glucose as well as medium alone (control were examined. Results. Cell number was higher in media supplemented with soft drinks, compared to control. Proliferation depended on the soft drink concentration and its origin, but not on sugar and calorific content. Conclusions. An unknown factor is responsible for the increase in proliferation.

  16. Implementing the strengthened non-proliferation regime in Georgia

    International Nuclear Information System (INIS)

    Chelidze, L.

    2009-01-01

    A few years ago Georgia faced complicated problems in nuclear and radiation safety field, namely: weakness of infrastructure for state management, incomplete inventory of radiation sources, orphan sources all over the post soviet military bases and as a result several radiological emergencies, overexposed victims and high risk of attracting international terrorists to use the country as a rout for illegal movement of radiation sources or nuclear materials. IAEA policy and strategy for nonproliferation showed that it is not the one country problem. The coalition of democratic countries immediately responded to aroused problems. Step by step Georgia established a regulatory body, worked out national legislation, developed licensing and inspection activities, nearly finished installation of radiation portals at the whole perimeter of the country. Several successful cases of prevention of the illicit trafficking of nuclear materials through borders of Georgia identified country's ability to contribute its shear to the Global Nuclear security.(author)

  17. Flaws in the Non-Proliferation Treaty

    International Nuclear Information System (INIS)

    Leventhal, P.

    1986-01-01

    The Treaty on the Non-Proliferation of Nucler Weapons has the twin objectives of stopping the further spread of nuclear weapons and ending the nuclear arms race on the one hand, and promoting peaceful uses of atomic energy on the other. In quantitative and symbolic terms the NPT is a huge success. More than two-thirds of the world's nations have signed on, making this the most popular arms control agreement on earth. Not a single nation has declared itself to be a nuclear-weapons state beyond the original five members of the ''nuclear club'' who qualified for weapons status under the terms of the Treaty itself: the United States, the Soviet Union, the United Kingdom, France, and China. No party to the Treaty has exercised the permitted option to drop out, and none has been found by the International Atomic Energy Agency (IAEA) to have diverted nuclear material from civil to weapons purposes. Nor has any party been known to have violated NPT prohibitions on developing or assisting other nations to develop nuclear weapons

  18. Statement to 2010 Review Conference of Parties to the Treaty on the Non-Proliferation of Nuclear Weapons (NPT), 3 May 2010, New York, USA

    International Nuclear Information System (INIS)

    Amano, Y.

    2010-01-01

    The IAEA works to prevent the proliferation of nuclear weapons and to promote the use of nuclear energy for peaceful purposes and technical cooperation. The IAEA also has a role to play in verifying nuclear disarmament. As all of these activities are relevant to the work of the NPT Review Conference, I would like to provide you with a brief overview of recent developments. As you know, reliable supplies of energy are vital to ensure continued prosperity and sustained development. Nuclear power is enjoying growing acceptance as a stable and clean source of energy that can help to mitigate the impact of climate change. More than 60 countries are considering introducing nuclear power to generate electricity. It is expected that between 10 and 25 new countries will bring their first nuclear power plants online by 2030. Certainly, it is for each sovereign State to decide whether or not to use nuclear power, but the IAEA assists interested countries in establishing a reliable nuclear infrastructure. Nuclear power must be accessible not only for developed countries but also for developing countries. Nuclear power needs to be efficient, sustainable and profitable. Any expansion in its use must be done safely and securely, and without increasing the proliferation risk.A successful NPT Review Conference is indispensable because it will enhance confidence in the non-proliferation regime, which in turn will provide the Agency with a stronger basis for our work in all areas

  19. The control of non-proliferation of nuclear weapons and nuclear development - present uncertainties

    International Nuclear Information System (INIS)

    Machado de Faria, N.G.; Amaral Barros, E.

    1983-01-01

    This report gives the views of Brazilian lawyers on the non-proliferation of nuclear weapons. It deals with the present situation and future prospects concerning the uses of nuclear energy. In particular, it proposes the preparation of a protocol prohibiting the use of nuclear weapons. (NEA) [fr

  20. Nuclear energy and non-proliferation in Latin America: the constitution of Tlatelolco system

    International Nuclear Information System (INIS)

    Armanet, P.

    1982-01-01

    The nuclear energy as alternative energy resource and its military use are analysed. Then the main characteristics of the Tratelolco treaty and non-proliferation in Latin America are discussed. Finally the importance of the nuclear-weapons-free zone in Latin America is shown. (A.B.T.) [pt

  1. Proliferation: myth or reality?; La proliferation: mythe ou realite?

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    This article analyzes the proliferation approach, its technical condition and political motivation, and the share between the myth (political deception, assumptions and extrapolations) and the reality of proliferation. Its appreciation is complicated by the irrational behaviour of some political actors and by the significant loss of the non-use taboo. The control of technologies is an important element for proliferation slowing down but an efficient and autonomous intelligence system remains indispensable. (J.S.)

  2. Nuclear Non-proliferation (Safeguards) Act 1987 - No 8 of 1987

    International Nuclear Information System (INIS)

    1987-01-01

    This Act aims at giving domestic legislative effect to Australia's international non-proliferation obligations and establishes controls over the possession and transport of nuclear materials and equipment by a system of permits. These obligations arise inter alia under the NPT Convention on the Physical Protection of Nuclear Material. The Act provides that its provisions shall apply to nuclear material (as defined in Article XX of the IAEA Statute) and associated items which include associated material, equipment or technology. These are clearly defined in the Act. (NEA) [fr

  3. Quantum fields in the non-perturbative regime. Yang-Mills theory and gravity

    Energy Technology Data Exchange (ETDEWEB)

    Eichhorn, Astrid

    2011-09-06

    In this thesis we study candidates for fundamental quantum field theories, namely non-Abelian gauge theories and asymptotically safe quantum gravity. Whereas the first ones have a stronglyinteracting low-energy limit, the second one enters a non-perturbative regime at high energies. Thus, we apply a tool suited to the study of quantum field theories beyond the perturbative regime, namely the Functional Renormalisation Group. In a first part, we concentrate on the physical properties of non-Abelian gauge theories at low energies. Focussing on the vacuum properties of the theory, we present an evaluation of the full effective potential for the field strength invariant F{sub {mu}}{sub {nu}}F{sup {mu}}{sup {nu}} from non-perturbative gauge correlation functions and find a non-trivial minimum corresponding to the existence of a dimension four gluon condensate in the vacuum. We also relate the infrared asymptotic form of the {beta} function of the running background-gauge coupling to the asymptotic behavior of Landau-gauge gluon and ghost propagators and derive an upper bound on their scaling exponents. We then consider the theory at finite temperature and study the nature of the confinement phase transition in d = 3+1 dimensions in various non-Abelian gauge theories. For SU(N) with N= 3,..,12 and Sp(2) we find a first-order phase transition in agreement with general expectations. Moreover our study suggests that the phase transition in E(7) Yang-Mills theory also is of first order. Our studies shed light on the question which property of a gauge group determines the order of the phase transition. In a second part we consider asymptotically safe quantum gravity. Here, we focus on the Faddeev-Popov ghost sector of the theory, to study its properties in the context of an interacting UV regime. We investigate several truncations, which all lend support to the conjecture that gravity may be asymptotically safe. In a first truncation, we study the ghost anomalous dimension

  4. Nuclear power generation and nuclear non-proliferation

    International Nuclear Information System (INIS)

    Rathjens, G.

    1979-01-01

    The main points existing between nuclear energy development and nuclear non-proliferation policy are reviewed. The solar energy and other energy will replace for nuclear fission energy in the twenty first century, but it may not occur in the first half, and the structure has to be established to continue the development of nuclear fission technology, including breeder reactor technology. In the near future, it should be encouraged to use advanced thermal reactors if they are economic and operated with safety. Miserable results may be created in the worldwide scale, if a serious accident occurs anywhere or nuclear power reactors are utilized for military object. It is estimated to be possible to develop the ability of manufacturing nuclear weapons within two or three years in the countries where the industry is highly developed so as to generate nuclear power. It is also difficult to take measures so that nuclear power generation does not increase nuclear proliferation problems, and it is necessary to mitigate the motive and to establish the international organization. Concensus exists that as the minimum security action, the storage and transportation of materials, which can be directly utilized for nuclear weapons, should be decided by the international system. The most portions of sensitive nuclear fuel cycle should be put under the international management, as far as possible. This problem is discussed in INFCE. Related to the nuclear nonproliferation, the difference of policy in fuel cycle problems between USA and the other countries, the enrichment of nuclear fuel material, especially the reasons to inhibit the construction of additional enrichment facilities, nuclear fuel reprocessing problems, radioactive waste disposal, plutonium stock and plutonium recycle problems are reviewed. (Nakai, Y.)

  5. Treaty on the non-proliferation of nuclear weapons: Review conference of the States Parties Geneva 1985

    International Nuclear Information System (INIS)

    1984-01-01

    The Third Review Conference of the Parties to the Treaty on the Non-Proliferation of Nuclear Weapons will be held in Geneva, Switzerland, in 1985 with a view to assuring that the purposes and provisions of the Treaty are being realized. The Treaty, commonly referred to as the non-proliferation Treaty, is the fundamental instrument to avert the danger of proliferation of nuclear weapons and is, perhaps, the most important multilateral arms regulation agreement of our time. It was negotiated in the 1960s in the Eighteen-Nation Committee on Disarmament in Geneva and in the United Nations General Assembly. The Treaty was opened for signature in London, Moscow and Washington on July 1, 1968. On that date, it was signed by the three Depositary Governments - the Soviet Union, the United Kingdom and the United States - and by 58 other States. As of December 31, 1983 the number of States parties to the Treaty had risen to 119

  6. Getting serious about proliferation

    International Nuclear Information System (INIS)

    Leventhal, P.

    1984-01-01

    The US needs to give a higher priority to nuclear non-proliferation, but Reagan's policies assume that proliferation is inevitable and that it is more important to be a reliable supplier than to cause trade frictions by trading only with those nations which sign the non-proliferation treaty (NPT). This undercuts US leadership and the intent of the agreement. Several bills now before Congress could help to restore US leadership by tightening export restrictions and the use of plutonium from the US

  7. Non-proliferation, safeguards, and security for the fissile materials disposition program immobilization alternatives

    Energy Technology Data Exchange (ETDEWEB)

    Duggan, R.A.; Jaeger, C.D.; Tolk, K.M. [Sandia National Labs., Albuquerque, NM (United States); Moore, L.R. [Lawrence Livermore National Lab., CA (United States)

    1996-05-01

    The Department of Energy is analyzing long-term storage and disposition alternatives for surplus weapons-usable fissile materials. A number of different disposition alternatives are being considered. These include facilities for storage, conversion and stabilization of fissile materials, immobilization in glass or ceramic material, fabrication of fissile material into mixed oxide (MOX) fuel for reactors, use of reactor based technologies to convert material into spent fuel, and disposal of fissile material using geologic alternatives. This paper will focus on how the objectives of reducing security and proliferation risks are being considered, and the possible facility impacts. Some of the areas discussed in this paper include: (1) domestic and international safeguards requirements, (2) non-proliferation criteria and measures, (3) the threats, and (4) potential proliferation, safeguards, and security issues and impacts on the facilities. Issues applicable to all of the possible disposition alternatives will be discussed in this paper. However, particular attention is given to the plutonium immobilization alternatives.

  8. Controlling nuclear proliferation

    International Nuclear Information System (INIS)

    Sweet, W.

    1981-01-01

    Nuclear non-proliferation policy depends on the 1968 Non-Proliferation Treaty, in which countries promise not to acquire nuclear weapons in exchange for open access to peaceful nuclear technology, and a system of international safeguards that are imposed on exported nuclear equipment and facilities operated by parties to the treaty. Critics have feared all along that non-nuclear countries might circumvent or exploit the system to obtain nuclear weapons and that the Atoms for Peace plan would spread the very technology it sought to control. The nuclear weapons states would like everyone else to believe that atomic bombs are undesirable, but they continue to rely on the bombs for their own defense. Israel's raid on Iraq's nuclear reactor focused world attention on the proliferation problem and helped to broaden and sterengthen its prospects. It also highlighted the weakness that there are no effective sanctions against violators. Until the international community can ageee on enforcement measures powerful enough to prevent nuclear proliferation, individual countries may be tempted to follow Israel's example, 19 references

  9. Problems of the nuclear non-proliferation policy. Contributions to the international discussion

    International Nuclear Information System (INIS)

    Blix, H.; Butler, P. von; Fischer, W.; Caccia Dominioni, F.; Frick, H.; Gmelin, W.; Haeckel, E.; Lauppe, W.D.; Mueller, H.; Richter, B.; Stein, G.

    1994-01-01

    The volume assembles a number of essays wherein basic problems of nonproliferation are identified and discussed in view of recent developments and future policy requirements. What is the role of multilateral institutions in the containment of nuclear proliferation? How are Western Europe's security needs to be reconciled with the tenets of the global nonproliferation regime? How can international safeguards be upgraded so as to increase confidence among states? What kinds of disciplinary instruments are needed for the international community to prevent an unco-operative state from gaining access to nuclear weapons? What kinds of obstacles stand in the way of smooth co-operation between the European Union and the United States in the nuclear field? How does the demise of global bipolarity impinge on the need to pursue an international nuclear order? The essays in this volume seek to combine structural analysis of conceptual issues with substantive policy recommendations. (orig./HP) [de

  10. Indonesia ratifies the treaty on non proliferation of nuclear weapons

    International Nuclear Information System (INIS)

    Moendi Poernomo

    1979-01-01

    By Act no. 8 of 1978 Indonesia ratified the treaty on the non proliferation of nuclear weapons. This means that Indonesia became a party to the treaty. Ratification does not guarantee that Indonesia will automatically obtain assistance in developing its nuclear technology capability, but in this way at least Indonesia demonstrates its intention to promote world peace as clearly stated in the Main Guide Lines of State Policy. Development of nuclear technology can be achieved through international cooperation with advanced countries without being suspected of having intention other than peace. (author)

  11. Between power and justice: current problems and perspectives of the NPT regime

    International Nuclear Information System (INIS)

    Mueller, Harald

    2010-01-01

    The nuclear non-proliferation regime, despite being frequently criticised for an alleged lack of effectiveness, is in fact an amazing success story. The number of states which had conducted nuclear weapons activities in various stages but which have terminated them at one point surpasses the number of Nuclear-Weapon States (NWSs) by far. At the apex of its success, however, the regime is threatened by erosion from three different directions. A small number of rule-breakers and outsiders under-mine its central objective: to stop the spread of nuclear weapons. The refusal of the official NWSs to fulfil their undertaking of nuclear disarmament violates the principle of justice enshrined in the treaty and thereby destroys its legitimacy, as does the perceived readiness by nuclear suppliers to impede the development of nuclear technology in developing countries. The Gordian Knot can presumably only be cut by a u-turn towards a world without nuclear weapons. This insight has meanwhile reached the mainstream security establishment of the United States, the president included. Whether this road will really be taken will determine the future of the regime-with far-reaching consequences for global security. (author)

  12. Lessons learned from the non-proliferation experiment

    Energy Technology Data Exchange (ETDEWEB)

    McWilliam, C.; Curtis, S. [DOE, Las Vegas, NV (United States)

    1994-12-31

    The Department of Energy sponsored Non-Proliferation Experiment (formerly known as the Chemical Kiloton) involved the detonation of blasting agent approximately equivalent to one kiloton of energy release on the Nevada Test Site in an effort to determine if (and if so, which) discriminators exist between conventional and nuclear detonations of similar yield. Coordination among hundreds of scientists from at least fifteen different organizations were required to design the experiments necessary to collect and interpret data from this unique and complex event. Stakeholders and members of the Group of Scientific Experts of the Conference on Disarmament observed the progress of the experiment first hand. The experiment was a success in that a vast majority of the expected data was collected and shared quickly and efficiently throughout the international scientific community. The management of the project was discussed among the major co-sponsoring organizations and the significant {open_quotes}lessons learned{close_quotes} are presented.

  13. Explosive performance on the non-proliferation experiment

    Energy Technology Data Exchange (ETDEWEB)

    McKown, T.O. [Los Alamos National Lab., NM (United States)

    1994-12-31

    The Explosive Effects Physics Project at the Los Alamos National Laboratory planned and conducted experiments on the Non-Proliferation Experiment (NPE) as part of its effort to define source functions for seismic waves. Since all investigations were contingent on the performance of the emplaced chemical explosive, an array of diagnostic measurements was fielded in the emplaced explosive. The CORRTEX (COntinuous Reflectometry for Radius vs Time EXperiment) system was used to investigate the explosive initiation and to determine the detonation velocities on three levels and in a number of radial directions. The CORRTEX experiments fielded in the explosive chamber will be described, including a description of the explosive emplacement from the perspective of its impact on the CORRTEX results. The data obtained are reviewed and the resulting detonation velocities are reported. A variation of detonation velocity with depth in the explosive and the apparent underdetonation and overdetonation of the explosive in different radial directions is reported.

  14. Non-genotoxic carcinogens: early effects on gap junctions, cell proliferation and apoptosis in the rat

    International Nuclear Information System (INIS)

    Mally, Angela; Chipman, James Kevin

    2002-01-01

    Non-genotoxic carcinogens are thought to induce tumour formation by disturbing the balance between cell growth and cell death. Gap junctions (GJ) contribute to the maintenance of tissue homeostasis by allowing the intercellular exchange of growth regulatory signals and potential inhibition of GJ intercellular communication through loss of connexin (Cx) plaques has been shown to be involved in the cancer process. We have investigated the time- and dose-dependent effects of the non-genotoxic hepatocarcinogens Wy-14,643, 2,3,7,8-tetrachlorodibenzo-p-dioxin, methapyrilene and hexachlorobenzene and the male rat kidney carcinogens chloroform, p-dichlorobenzene and d-limonene on gap junction plaque expression in relation to proliferation and apoptosis. With the exception of limonene, all non-genotoxic carcinogens significantly reduced the expression of GJ plaques containing Cx32 in their respective target tissue. No dose-dependent, significant effects were seen in non-target organs. Although alteration of Cx32 expression did not appear to correlate with induction of cell proliferation, out data suggest that the interaction of both processes--interference of GJ coupled with a proliferative stimulus (at the carcinogenic dose)--may be important in non-genotoxic carcinogenesis and provide a potential alert for non-genotoxic carcinogens in short-term toxicity tests

  15. The threat of proliferation

    International Nuclear Information System (INIS)

    Palme, Olof.

    1986-01-01

    The paper on the threat of proliferation, is a keynote speech delivered to the Colloquium on Nuclear War, Nuclear Proliferation and their Consequences, Geneva, 1985. Topics discussed in the address include: nuclear weapons, nuclear war, terrorists, Non-Proliferation Treaty, nuclear disarmament, and leadership in world affairs. (UK)

  16. Down-regulation of long non-coding RNA TUG1 inhibits osteosarcoma cell proliferation and promotes apoptosis.

    Science.gov (United States)

    Zhang, Qiang; Geng, Pei-Liang; Yin, Pei; Wang, Xiao-Lin; Jia, Jin-Peng; Yao, Jie

    2013-01-01

    To investigate the expression level of TUG1 and one of its transcript variants (n377360) in osteosarcoma cells and assess the role of TUG1 in proliferation and apoptosis in the U2OS cell line. TUG1 and n377360 expression levels in patients with osteosarcomas and the U2OS human osteosarcoma cell line were evaluated using real-time quantitative PCR. U2OS cells were transected with TUG1 and n377360 siRNA or non-targeting siRNA. MTS was performed to assess the cell proliferation and flow cytometry was applied to analyze apoptosis. We found significantly higher TUG1 and n377360 expression levels in osteosarcoma tissues compared with matched non-tumorous tissues. In line with this, suppression of TUG1 and n377360 expression by siRNA significantly impaired the cell proliferation potential of osteosarcoma cells. Furthermore, inhibition of TUG1 expression significantly promoted osteosarcoma cell apoptosis. The overexpression of TUG1 and n377360 in osteosarcoma specimens and the functional role of TUG1 and n377360 regarding cell proliferation and apoptosis in an osteosarcoma cell line provided evidence that the use of TUG1 or n377360 may be a viable but an as yet unexplored therapeutic strategy in tumors that over express these factors.

  17. The third review conference of the parties of the Treaty on Non-Proliferation of Nuclear Weapons, and recent developments concerning international safeguards

    International Nuclear Information System (INIS)

    Canty, M.J.; Richter, B.; Schlupp, C.; Stein, G.

    1986-11-01

    The non-proliferation activities and instruments are listed in a table. The two main instruments are the Non-Proliferation Treaty and the IAEA Safeguards, which are supplemented by treaties of regional restricted effects, such as the Treaty of Tlatelolco and the EURATOM treaty. The two-tier structure of the treaties, i.e. to provide for non-proliferation of nuclear weapons and at the same time foster the peaceful uses of nuclear energy, has proven to have a particularly stabilizing effect, which was confirmed by the last Review Conference of the Parties to the Treaty on Non-Proliferation. The conference members were particularly satisfied with the results of the IAEA Safeguards. Future developments towards improving international safeguards will concentrate on operator-friendly and financially reasonable safeguards measures, such as safeguards effectiveness evaluations and near-real-time accountancy. The results of the CAS discussions on the definition of principles and goals of co-operation for the peaceful uses of nuclear energy are of importance also to the PUNE conference. The PUNE conference will be held in 1987 and is expected to yield points of orientation for further embedding the non-proliferation principle in the international co-operative activities and the nuclear business in the 1980s. (orig./HP) [de

  18. Non-multipotent stroma inhibit the proliferation and differentiation of mesenchymal stromal cells in vitro.

    Science.gov (United States)

    Rosu-Myles, Michael; Fair, Joel; Pearce, Nelson; Mehic, Jelica

    2010-10-01

    The ability to expand and maintain bone marrow (BM)-derived mesenchymal stem cells (MSC) in vitro is an important aspect of their therapeutic potential. Despite this, the exact composition of stromal cell types within these cultures and the potential effects of non-stem cells on the maintenance of MSC are poorly understood. C57BL/6J BM stroma was investigated as a model to determine the relationship between MSC and non-multipotent cells in vitro. Whole BM and single-cell derived cultures were characterized using flow cytometry and cell sorting combined with multipotent differentiation. Proliferation of individual stromal populations was evaluated using BrdU. At a single-cell level, MSC were distinguished from committed progenitors, and cells lacking differentiation ability, by the expression of CD105 (CD105+). A 3-fold reduction in the percentage of CD105+ cells was detected after prolonged culture and correlated with loss of MSC. Depletion of CD105+ cells coincided with a 10-20% increase in the frequency of proliferating CD105(-) cells. Removal of CD105(-) stroma caused increased proliferation in CD105+ cells, which could be diminished by conditioned media from parent cultures. Comparison of the multipotent differentiation potential in purified and non-purified CD105+ cells determined that MSC were detectable for at least 3 weeks longer when cultured in the absence of CD105(-) cells. This work identifies a simple model for characterizing the different cellular components present in BM stromal cultures and demonstrates that stromal cells lacking multipotent differentiating capacity greatly reduce the longevity of MSC.

  19. Intelligence and Nuclear Proliferation: Lessons Learned

    International Nuclear Information System (INIS)

    Hansen, Keith A.

    2011-09-01

    Intelligence agencies play a fundamental role in the prevention of nuclear proliferation, as they help to understand other countries' intentions and assess their technical capabilities and the nature of their nuclear activities. The challenges in this area remain, however, formidable. Past experiences and the discoveries of Iraq's WMD programs, of North Korean nuclear weapon program, and of Iranian activities, have put into question the ability of intelligence to monitor small, clandestine proliferation activities from either states or non-state entities. This Proliferation Paper analyzes the complex challenges intelligence faces and the various roles it plays in supporting national and international nuclear non-proliferation efforts, and reviews its track record. In an effort to shed light on the role and contribution of intelligence in national and international efforts to halt, if not prevent, further nuclear weapon proliferation, this paper first analyzes the challenges intelligence faces in monitoring small, clandestine proliferation activities and the role it plays in supporting non-proliferation efforts. It then reviews the intelligence track record in monitoring proliferation including the lessons learned from Iraq. Finally, it addresses whether it is possible for intelligence to accurately monitor future clandestine proliferation efforts. (author)

  20. The non-proliferation experiment

    Energy Technology Data Exchange (ETDEWEB)

    Hannon, W.J. [Lawrence Livermore National Lab., CA (United States)

    1994-12-31

    On September 22, 1993, the Department of Energy detonated more than 1.2 million kg of blasting agent in a tunnel in Rainier Mesa at the Nevada Test Site. The resulting explosion generated seismic, electromagnetic, and air pressure signals that were recorded on instruments deployed at distances ranging from a few meters to hundreds and, in some cases, thousands of kilometers. More than 12 organizations made measurements before, during, and after the explosions. The explosion and its associated experiments are known as the Non-Proliferation Experiment (NPE). Analyses of the measurements made during the NPE and comparisons with similar measurements made on previous nearly nuclear explosions and on a co-located smaller explosion detonated at the same site are providing basic phenomenological insights into what is potentially one of the comprehensive Test Ban Treaty (CTBT)-distinguishing between nuclear explosions and some of the many conventional explosions that occur each year. The NPE is also providing information on the use of chemical explosions to develop empirical discriminants in regions where no nuclear explosions have been recorded. In another verification application, several NPE projects are examining the utility of on-site, pre-shot, shot-time, and post-shot measurements of gas seepage, seismic activity, and other observables as a means of identifying the source of signals that appear like nuclear explosions at regional distances. Two related activities are being considered. First, challenge on-site inspections, conducted after an event has occurred, may be able to use the characteristics of phenomena that persist after the explosion to detect and identify the source of the signals that appeared ambiguous or explosion-like to remote sensors. Second, cooperative, on-site measurements made at the time of a pre-nounced conventional explosion may provide assurance that a nuclear explosion did not occur as part of or in place of the pre-announced explosion.

  1. Scientists for non-proliferation of nuclear weapons. Transactions of international seminar

    International Nuclear Information System (INIS)

    1994-01-01

    This publication presents the results of the Second International Seminar 'Scientists for Non-Proliferation of Nuclear Weapons'. The Seminar took place from 11 to 14 October 1994 in Nakhabino Country Club near Moscow. More than 60 specialists from Russia, USA, France, Belgium as well as IAEA and CEU took part in the seminar. Problems of cooperation in the field of nuclear materials accounting, control and safeguards, physical protection of nuclear materials, nuclear export regulations and disarmament control are discussed at the seminar

  2. Nuclear weapon-free zone, non-proliferation treaty and South Asia

    International Nuclear Information System (INIS)

    Jayaramu, P.S.

    1980-01-01

    Emergence of and the motivations behind the concept of nuclear weapon free zone, the conceptual linkage between the nuclear weapon free zone and the Non-Proliferation Treaty and the problems involved in the implementation of nuclear weapon free zone proposals put forward from time to time are discussed. Pakistan's proposal for a nuclear weapon free zone in South Asia, motivations behind the proposal, and India's response to it are examined. It is pointed out that both the NPT and nuclear weapon free zone indirectly grant a certain amount of legitimacy to the use of nuclear weapons. (M.G.B.)

  3. The effects of radiofrequency fields on cell proliferation are non-thermal.

    Science.gov (United States)

    Velizarov, S; Raskmark, P; Kwee, S

    1999-02-01

    The number of reports on the effects induced by radiofrequency (RF) electromagnetic fields and microwave (MW) radiation in various cellular systems is still increasing. Until now no satisfactory mechanism has been proposed to explain the biological effects of these fields. One of the current theories is that heat generation by RF/MW is the cause, in spite of the fact that a great number of studies under isothermal conditions have reported significant cellular changes after exposure to RF/MW. Therefore, this study was undertaken to investigate which effect MW radiation from these fields in combination with a significant change of temperature could have on cell proliferation. The experiments were performed on the same cell line, and with the same exposure system as in a previous work [S. Kwee, P. Raskmark, Changes in cell proliferation due to environmental non-ionizing radiation: 2. Microwave radiation, Bioelectrochem. Bioenerg., 44 (1998), pp. 251-255]. The field was generated by signal simulation of the Global System for Mobile communications (GSM) of 960 MHz. Cell cultures, growing in microtiter plates, were exposed in a specially constructed chamber, a Transverse Electromagnetic (TEM) cell. The Specific Absorption Rate (SAR) value for each cell well was calculated for this exposure system. However, in this study the cells were exposed to the field at a higher or lower temperature than the temperature in the field-free incubator i.e., the temperature in the TEM cell was either 39 or 35 +/- 0.1 degrees C. The corresponding sham experiments were performed under exactly the same experimental conditions. The results showed that there was a significant change in cell proliferation in the exposed cells in comparison to the non-exposed (control) cells at both temperatures. On the other hand, no significant change in proliferation rate was found in the sham-exposed cells at both temperatures. This shows that biological effects due to RF/MW cannot be attributed only to a

  4. Linear and non-linear calculations of the hose instability in the ion-focused regime

    International Nuclear Information System (INIS)

    Buchanan, H.L.

    1982-01-01

    A simple model is adopted to study the hose instability of an intense relativistic electron beam in a partially neutralized, low density ion channel (ion focused regime). Equations of motion for the beam and the channel are derived and linearized to obtain an approximate dispersion relation. The non-linear equations of motion are then solved numerically and the results compared to linearized data

  5. Surface modification of biphasic calcium phosphate scaffolds by non-thermal atmospheric pressure nitrogen and air plasma treatment for improving osteoblast attachment and proliferation

    International Nuclear Information System (INIS)

    Choi, Yu-Ri; Kwon, Jae-Sung; Song, Doo-Hoon; Choi, Eun Ha; Lee, Yong-Keun; Kim, Kyoung-Nam; Kim, Kwang-Mahn

    2013-01-01

    Surface modifications induced by non-thermal plasma have been used extensively in biomedical applications. The attachment and proliferation of osteoblast cells are important in bone tissue engineering using scaffolds. Hence the effect of non-thermal plasma on hydroxyapatite/β-tri-calcium phosphate (HA/β-TCP) scaffolds in terms of improving osteoblast attachment and proliferation was investigated. Experimental groups were treated with non-thermal plasma for 10 min and 20 min and a control group was not treated with non-thermal plasma. For surface chemistry analysis, X-ray photoelectron spectroscopy (XPS) analysis was carried out. The hydrophilicity was determined from contact angle measurement on the surface. Atomic force microscopy analysis (AFM) was used to test the change in surface roughness and cell attachment and proliferation were evaluated using MC3T3-E1 osteoblast cells. XPS spectra revealed a decreased amount of carbon on the surface of the plasma-treated sample. The contact angle was also decreased following plasma treatment, indicating improved hydrophilicity of plasma-treated surfaces compared to the untreated disc. A significant increase in MC3T3E-1 cell attachment and proliferation was noted on plasma-treated samples as compared to untreated specimens. The results suggest that non-thermal atmospheric pressure nitrogen and air plasma treatments provide beneficial surface characteristics on HA/β-TCP scaffolds. - Highlights: ► Non-thermal plasma increased OH- and decreased C on biphasic scaffold. ► Non-thermal plasma had no effect on surface roughness. ► Non-thermal plasma resulted in hydrophilic surface. ► Non-thermal plasma resulted in better cell attachment and proliferation. ► Non-thermal plasma treatment on biphasic scaffold is useful for tissue engineering

  6. Nuclear proliferation and civilian nuclear power: report of the Nonproliferation Alternative Systems Assessment Program. Volume VII. International perspectives

    International Nuclear Information System (INIS)

    1979-12-01

    The purpose of this volume is to assess the proliferation vulnerabilities of the present deployment of civilian nuclear-power systems within the current nonproliferation regime and, in light of their prospective deployment, to consider technical and institutional measures and alternatives which may contribute to an improved regime in which nuclear power could play a significant part. An assessment of these measures must include consideration of their nonproliferation effectiveness as well as their bearing upon energy security, and their operational, economic, and political implications. The nature of these considerations can provide some measure of their likely acceptability to various nations. While any final assessment of such measures and alternatives would have to examine the circumstances particular to each nation, it is hoped that the more generic assessments conducted here will be useful in suggesting guidelines for developing an improved nonproliferation regime which also helps to meet nuclear-energy needs. One chapter outlines the existing nonproliferation regime, including the Treaty for the Non-Proliferation of Nuclear Weapons (NPT), International Atomic Energy Agency (IAEA) safeguards, bilateral and multilateral requirements for agreements of cooperation and transfers of technology, and existing provisons for sanctions for violation of nonproliferation commitments. The chapter then proceeds to an assessment of various alternatives for providing assurance of fuel supply in light of this current regime. Another chapter examines a set of technical and institutional measures and alternatives for various components of once-through and closed fuel cycles. The components of the once-through fuel cycle assessed are enrichment services and spent-fuel management; the components of closed fuel cycles assessed are reprocessing and plutonium management and fast-breeder reactor (FBR) deployment

  7. Effects of non-steroidal anti-inflammatory drugs on cell proliferation and death in cultured epiphyseal-articular chondrocytes of fetal rats

    International Nuclear Information System (INIS)

    Chang, J.-K.; Wu, S.-C.; Wang, G.-J.

    2006-01-01

    Previous reports indicated that non-steroidal anti-inflammatory drugs (NSAIDs) suppress bone repair. Our previous study further found that ketorolac delayed the endochondral bone formation, and the critical effective timing was at the early stage of repair. Furthermore, we found that NSAIDs suppressed proliferation and induced cell death of cultured osteoblasts. In this study, we hypothesized that chondrocytic proliferation and death, which plays an important role at the early stage of endochondral bone formation, might be affected by NSAIDs. Non-selective NSAIDs, indomethacin, ketorolac, diclofenac and piroxicam; cyclooxygenase-2 (COX-2) selective NSAIDs, celecoxib and DFU (an analog of rofecoxib); prostaglandins (PGs), PGE1, PGE2 and PGF2α; and each NSAID plus each PG were tested. The effects of NSAIDs on proliferation, cell cycle kinetics, cytotoxicity and cell death of epiphyseal-articular chondrocytes of fetal rats were examined. The results showed that all the tested NSAIDs, except DFU, inhibited thymidine incorporation of chondrocytes at a concentration range (10 -8 to 10 -4 M) covering the theoretic therapeutic concentrations. Cell cycle was arrested by NSAIDs at the G /G 1 phase. Upon a 24 h treatment, LDH leakage and cell death (both apoptosis and necrosis) were significantly induced by the four non-selective NSAIDs in chondrocyte cultures. However, COX-2 inhibitors revealed non-significant effects on cytotoxicity of chondrocytes except higher concentration of celecoxib (10 -4 M). Replenishments of PGE1, PGE2 or PGF2α could not reverse the effects of NSAIDs on chondrocytic proliferation and cytotoxicity. In this study, we found that therapeutic concentrations of non-selective NSAIDs caused proliferation suppression and cell death of chondrocytes, suggesting these adverse effects may be one of the reasons that NSAIDs delay the endochondral ossification during bone repair found in previous studies. Furthermore, these effects of NSAIDs may act via PG

  8. Defining the new initiatives of struggle against the proliferation of arms of massive destruction

    International Nuclear Information System (INIS)

    Hautecouverture, Benjamin

    2007-01-01

    The author discusses the various terms of the concept of 'new initiatives of struggle against arms of massive destruction' by discussing how these initiatives are new, how they address new threats (State-based proliferation of AMD, terrorism of massive destruction). He comments the background of these initiatives which may be launched to respond to a specific threat or to implement specific means of struggle. He identifies the main characteristics of these political or institutional initiatives: they are pragmatic, functional, instrumental, have different scopes, are based on an institutional flexibility, and on cooperation and partnership. For different of these initiatives (Proliferation Security Initiative, Container Security Initiative, Global Initiative to Combat Nuclear Terrorism, and so on), the author indicates whether they are unilateral, bilateral, supported by regional organisations, by the UN, by operational international organisations, or inter-governmental groups. He finally outlines questions raised by these initiatives: how to assess their impact? Must they be more integrated? Can they or must they have a better defined role in the global regime of non proliferation and disarmament?

  9. Quantum resource theory of non-stabilizer states in the one-shot regime

    Science.gov (United States)

    Ahmadi, Mehdi; Dang, Hoan; Gour, Gilad; Sanders, Barry

    Universal quantum computing is known to be impossible using only stabilizer states and stabilizer operations. However, addition of non-stabilizer states (also known as magic states) to quantum circuits enables us to achieve universality. The resource theory of non-stablizer states aims at quantifying the usefulness of non-stabilizer states. Here, we focus on a fundamental question in this resource theory in the so called single-shot regime: Given two resource states, is there a free quantum channel that will (approximately or exactly) convert one to the other?. To provide an answer, we phrase the question as a semidefinite program with constraints on the Choi matrix of the corresponding channel. Then, we use the semidefinite version of the Farkas lemma to derive the necessary and sufficient conditions for the conversion between two arbitrary resource states via a free quantum channel. BCS appreciates financial support from Alberta Innovates, NSERC, China's 1000 Talent Plan and the Institute for Quantum Information and Matter.

  10. Defining an Effective Approach to Non-Proliferation in Northeast Asia

    Institute of Scientific and Technical Information of China (English)

    Pan; Zhenqiang

    2014-01-01

    <正>As in Europe,the nuclear issues have been a central element in the security in Northeast Asia.The region assembles a group of non-nuclear weapon states that may potentially go nuclear.Today,despite the increasing fading away of the danger of a major nuclear exchange among major powers,nuclear proliferation is emerging as a new major source of insecurity in the region,and how to tackle this risk has become a daunting challenge for all the countries concerned.Since the end of the Cold War,in the Korean Peninsula nuclear issue,the DPRK so far has ignited three nuclear weapon tests,been

  11. Non-canonical microRNAs miR-320 and miR-702 promote proliferation in Dgcr8-deficient embryonic stem cells

    International Nuclear Information System (INIS)

    Kim, Byeong-Moo; Choi, Michael Y.

    2012-01-01

    Highlights: ► Embryonic stem cells (ESCs) lacking non-canonical miRNAs proliferate slower. ► miR-320 and miR-702 are two non-canonical miRNAs expressed in ESCs. ► miR-320 and miR-702 promote proliferation of Dgcr8-deficient ESCs. ► miR-320 targets p57 and helps to release Dgcr8-deficient ESCs from G1 arrest. ► miR-702 targets p21 and helps to release Dgcr8-deficient ESCs from G1 arrest. -- Abstract: MicroRNAs are known to contribute significantly to stem cell phenotype by post-transcriptionally regulating gene expression. Most of our knowledge of microRNAs comes from the study of canonical microRNAs that require two sequential cleavages by the Drosha/Dgcr8 heterodimer and Dicer to generate mature products. In contrast, non-canonical microRNAs bypass the cleavage by the Drosha/Dgcr8 heterodimer within the nucleus but still require cytoplasmic cleavage by Dicer. The function of non-canonical microRNAs in embryonic stem cells (ESCs) remains obscure. It has been hypothesized that non-canonical microRNAs have important roles in ESCs based upon the phenotypes of ESC lines that lack these specific classes of microRNAs; Dicer-deficient ESCs lacking both canonical and non-canonical microRNAs have much more severe proliferation defect than Dgcr8-deficient ESCs lacking only canonical microRNAs. Using these cell lines, we identified two non-canonical microRNAs, miR-320 and miR-702, that promote proliferation of Dgcr8-deficient ESCs by releasing them from G1 arrest. This is accomplished by targeting the 3′-untranslated regions of the cell cycle inhibitors p57 and p21 and thereby inhibiting their expression. This is the first report of the crucial role of non-canonical microRNAs in ESCs.

  12. Proliferation after the Iraq war; La proliferation apres la guerre d'Irak

    Energy Technology Data Exchange (ETDEWEB)

    Daguzan, J.F

    2004-09-15

    This article uses the Iraq war major event to analyze the approach used by the US to fight against proliferation. It questions the decision and analysis process which has led to the US-British intervention and analyzes the consequences of the war on the proliferation of other countries and on the expected perspectives. Finally, the future of proliferation itself is questioned: do we have to fear more threat or is the virtuous circle of non-proliferation well started? (J.S.)

  13. Internationalization: an alternative to nuclear proliferation

    International Nuclear Information System (INIS)

    Meller, E.

    1980-01-01

    Leading personalities in the field of nuclear energy worldwide assess possible improvements to the present nonproliferation regime and explore the possibilities for the internationalization of sensitive parts of the nuclear fuel cycle. Their studies address past and current nonproliferation policies, the current controversy between the United States and its European allies on the development of fast breeder reactors and plutonium recycling, implications of the recent US Non-Proliferation Act of 1978 upon US/Euratom relations, industrial government relationships, safety concerns, and the special needs of developing countries. Their conclusions stress the recognition of complex factors such as military security, technical competition, the spread of nuclear technology, and politics that will limit any mechanism to govern nonproliferation. They urge greater effort in educating the public to the political and economic complexities of nuclear power and recommend strengthening international agreements and other arrangements, including controls and safeguards, and the general rules for the international trade of nuclear fuel. 11 figures, 7 tables

  14. Suggested non-proliferation criteria for commercial nuclear fuel cycles

    International Nuclear Information System (INIS)

    Laney, R.V.; Heubotter, P.R.

    1978-01-01

    Based on the Administration's policy to prevent nuclear weapons proliferation through diversion of fuel from commercial reactor fuel cycles, a ''benchmark'' set of nonproliferation criteria was prepared for the commercial nuclear fuel cycle. These criteria should eliminate incremental risks of proliferation beyond those inherent in the present generation of low-enriched-uranium-fueled reactors operating in a once-through mode, with internationally safeguarded storage of spent fuel. They focus on the balanced application of technical constraints consistent with the state of the technology, with minimal requirements for institutional constraints, to provide a basis for assessing the proliferation resistance of proposed fission power systems. The paper contains: (1) our perception of the nuclear energy policy and of the baseline proliferation risk accepted under this policy; (2) objectives for a reactor and fuel cycle strategy which address the technical, political, and institutional aspects of diversion and proliferation and, at the same time, satisfy the Nation's needs for efficient, timely, and economical utilization of nuclear fuel resources; (3) criteria which are responsive to these objectives and can therefore be used to screen proposed reactor and fuel cycle strategies; and (4) a rationale for these criteria

  15. AN ANALYTICAL FRAMEWORK FOR ASSESSING RELIABLE NUCLEAR FUEL SERVICE APPROACHES: ECONOMIC AND NON-PROLIFERATION MERITS OF NUCLEAR FUEL LEASING

    International Nuclear Information System (INIS)

    Kreyling, Sean J.; Brothers, Alan J.; Short, Steven M.; Phillips, Jon R.; Weimar, Mark R.

    2010-01-01

    The goal of international nuclear policy since the dawn of nuclear power has been the peaceful expansion of nuclear energy while controlling the spread of enrichment and reprocessing technology. Numerous initiatives undertaken in the intervening decades to develop international agreements on providing nuclear fuel supply assurances, or reliable nuclear fuel services (RNFS) attempted to control the spread of sensitive nuclear materials and technology. In order to inform the international debate and the development of government policy, PNNL has been developing an analytical framework to holistically evaluate the economics and non-proliferation merits of alternative approaches to managing the nuclear fuel cycle (i.e., cradle-to-grave). This paper provides an overview of the analytical framework and discusses preliminary results of an economic assessment of one RNFS approach: full-service nuclear fuel leasing. The specific focus of this paper is the metrics under development to systematically evaluate the non-proliferation merits of fuel-cycle management alternatives. Also discussed is the utility of an integrated assessment of the economics and non-proliferation merits of nuclear fuel leasing.

  16. Non-proliferation of nuclear weapons - crisis of a concept

    International Nuclear Information System (INIS)

    Eisenbart, C.; Ehrenstein, D. von

    1990-01-01

    The Working Group of FEST (Protestant Study Community) and VDW (Association of German Scientists) presents twelve theses on the policy of non-proliferation of nuclear weapons and deduces recommendations, in particular for the Federal Government. The WG thinks that scope and significance of international nuclear policy has not been sufficiently perceived neither by the German public nor by politicians. The theses are supplemented and explained in more detail by special contributions of the WG's members. The contributions deal with the historical background, with the instruments of NP policy, with international law, with risks and limiting these risks, with economic aspects, with nuclear policy in the Third World, with the chances of nuclear disarmament, and with Federal NP policy. The 'twelve theses' as well as the 22 contributions are individual records. (HSCH) [de

  17. Differential expression of peroxisome proliferator activated receptor gamma and cyclin D1 does not affect proliferation of asthma- and non-asthma-derived airway smooth muscle cells

    NARCIS (Netherlands)

    Lau, Justine Y; Oliver, Brian G; Moir, Lyn M; Black, Judith L; Burgess, Janette K

    UNLABELLED: PPARgamma levels in asthma- and non-asthma-derived airway smooth muscle cells and PPARgamma activation-induced cell proliferation were investigated. In the presence of FBS, PPARgamma levels were higher in subconfluent asthma-derived cells but lower in confluent cells compared with

  18. A dynamic model for firm-response to non-credible incentive regulation regimes

    International Nuclear Information System (INIS)

    Agrell, Per J.; Grifell-Tatjé, Emili

    2016-01-01

    Economic network regulation increasingly use quantitative performance models (from econometrics and engineering) to set revenues. In theory, high-powered incentive regulation, such as revenue-caps, induces firms to cost-efficient behavior independent of underlying model. However, anecdotal evidence shows regulated firms occasionally maintaining cost-inefficiency under incentive regulation even under slumping profitability. We present a model for firm-level efficiency under a regime with a probability of failure explaining this phenomenon. The model is based on the hypothesis that the regulatory choice of method can be associated with intrinsic flaws leading to judicial repeal and replacement of it by a low-powered regime. The results show that the cost efficiency policy is proportional to the type of firm (cost of effort), value of time (discount factor) and the credibility of the method (risk of failure). A panel data set for 2000–2006 for 128 electricity distributors in Sweden is used to validate the model predictions (radical productivity slowdown, failing profitability and efficiency) at the launch and demise of a non-credible regulation method. The work highlights the fallacy of viewing incentive regulation as a method-independent instrument, a result applicable in any infrastructure regulation. - Highlights: • Incentive regulation relies on fixed revenue for operators. • In existing theory the efficiency-inducing effect is model-independent. • A dynamic game exposes the firm to a regulation that may fail. • One optimal policy is to pad cost and wait for the failure. • The Swedish DSOs show this policy 2003–2006, when the regime failed.

  19. Non-proliferation and nuclear disarmament: A status report. Vienna, 14 March 2001

    International Nuclear Information System (INIS)

    ElBaradei, M.

    2001-01-01

    For more than half a century, strategies of national and international security have been intertwined with the concept of nuclear weapons as a strategic deterrent. Further meaningful progress towards a nuclear weapon free world will demand that we re-examine our fundamental concept of what security means and how it can best be achieved. The following specific areas where our attention should be focused are discussed briefly: the historical perspective, current strategies for non-proliferation and disarmament, and the future prospects

  20. Nuclear export policy and regulation for non-proliferation: Federal Republic of Germany

    International Nuclear Information System (INIS)

    Boulanger, Werner.

    1978-01-01

    The nuclear export policy of the Federal Republic of Germany complies with the principle of non-proliferation of nuclear weapons. Already in 1967 the Federal Government stated in a Peace Note that no export was authorised to countries (outside Euratom) which did not comply with the IAEA Safeguards. In the bilateral agreement the Federal Republic signed with Brasil in 1975, emphasis was put on international safeguards and the control exercised on exported materials to avoid any diversion for military purposes. (NEA) [fr

  1. The Non-Proliferation Experiment recorded at the Pinedale Seismic Research Facility

    Energy Technology Data Exchange (ETDEWEB)

    Carr, D.B. [Sandia National Laboratories, Albuquerque, NM (United States)

    1994-12-31

    The Non-Proliferation Experiment was recorded by five different seismic stations operated by Sandia National Laboratories at the Pinedale Seismic Research Facility, approximately 7.6{degrees} from the Nevada Test Site. Two stations are different versions of the Deployable Seismic Verification System developed by the Department of Energy to provide seismic data to verify compliance with a Comprehensive Test Ban Treaty. Vault and borehole versions of the Designated Seismic Stations also recorded the event. The final station is test instrumentation located at depths of 10, 40 and 1200 feet. Although the event is seen clearly at all the stations, there are variations in the raw data due to the different bandwidths and depths of deployment. One Deployable Seismic Verification System has been operating at Pinedale for over three years and in that time recorded 14 nuclear explosions and 4 earthquakes from the Nevada Test Site, along with numerous other western U.S. earthquakes. Several discriminants based on the work by Taylor et al. (1989) have been applied to this data. First the discriminants were tested by comparing the explosions only to the 4 earthquakes located on the Test Site. Only one discriminant, log(L{sub g}/P{sub g}), did not show clear separation between the earthquakes and nuclear explosions. When other western U.S. events are included, only the M{sub b} vs. M{sub s} discriminant separated the event. In all cases where discrimination was possible, the Non-Proliferation Experiment was indistinguishable from a nuclear explosion.

  2. Casein kinase II is elevated in solid human tumours and rapidly proliferating non-neoplastic tissue

    DEFF Research Database (Denmark)

    Münstermann, U; Fritz, G; Seitz, G

    1990-01-01

    Protein kinase CKII (i.e. casein kinase II, CKII, NII) is expressed at a higher level in rapidly proliferating tissues and in solid human tumours (e.g. colorectal carcinomas) when compared to the corresponding non-neoplastic colorectal mucosa. This could be shown by (a) Western blotting of cellular...

  3. Transition from weak wave turbulence regime to solitonic regime

    Science.gov (United States)

    Hassani, Roumaissa; Mordant, Nicolas

    2017-11-01

    The Weak Turbulence Theory (WTT) is a statistical theory describing the interaction of a large ensemble of random waves characterized by very different length scales. For both weak non-linearity and weak dispersion a different regime is predicted where solitons propagate while keeping their shape unchanged. The question under investigation here is which regime between weak turbulence or soliton gas does the system choose ? We report an experimental investigation of wave turbulence at the surface of finite depth water in the gravity-capillary range. We tune the wave dispersion and the level of nonlinearity by modifying the depth of water and the forcing respectively. We use space-time resolved profilometry to reconstruct the deformed surface of water. When decreasing the water depth, we observe a drastic transition between weak turbulence at the weakest forcing and a solitonic regime at stronger forcing. We characterize the transition between both states by studying their Fourier Spectra. We also study the efficiency of energy transfer in the weak turbulence regime. We report a loss of efficiency of angular transfer as the dispersion of the wave is reduced until the system bifurcates into the solitonic regime. This project has recieved funding from the European Research Council (ERC, Grant Agreement No. 647018-WATU).

  4. Nuclear non proliferation. To declare, to support, and to analyse

    International Nuclear Information System (INIS)

    Anon.

    2016-01-01

    While proposing a brief presentation of the three main stages of an inspection (from the notification and preparation to the implementation of corrective actions), and a brief interview of a member of the French Euratom technical Committee (CTE) who presents this body and its role, this article proposes an overview of the commitment and practices of the IRSN regarding nuclear non-proliferation. It recalls that the control of nuclear materials is required by the Euratom Treaty, describes how the IRSN supports industrials to facilitate inspections made by the European Commission, and helps them in answering the post-inspection letter and in implementing corrective actions. It also evokes the role of the IRSN in nuclear material accounting

  5. The USA and proliferation in Northeast Asia

    International Nuclear Information System (INIS)

    Weeks, S.B.

    1995-01-01

    United States policy on proliferation in Northeast Asia poses a test of balance between general US global non-proliferation goals and specific US regional security goals for Northeast Asia. US policy on proliferation in Northeast Asia further poses a test of priorities for US bilateral relations with the key Northeast Asian states, as non-proliferation and regional security goals must be weighed against other (e.g., economic, human rights) declared US policy goals. The result is a US policy equation for Northeast Asia proliferation that is considerably more complex in execution than might be expected from the simple statement of the US goal to avoid nuclear proliferation in Northeast Asia. The question of security assurances - both negative and positive - may be closely related to US policies to avoid proliferation in Northeast Asia

  6. Non-proliferation and confidence-building measures in Asia and the Pacific

    International Nuclear Information System (INIS)

    1992-01-01

    In the face of improved international relations, regional and subregional issues have acquired additional urgency and importance in the field of disarmament and international security. The pursuit of regional solutions to regional problems is thus being actively encouraged by the international community. Towards this end, the United Nations Office for Disarmament Affairs is seeking to promote regional approaches to disarmament either through the united nations regional centres for peace and Disarmament or cooperation with individual Governments. Within this framework this conference was dealing with non-proliferation and confidence-building measures in Asia and the Pacific region

  7. Can Old Regimes Handle New Wars?

    DEFF Research Database (Denmark)

    Henningsen, Troels

    Research on New Wars argues that since the 1980s states and regimes have become more vulnerable to violence from non-state actors. Two developments in the Sahel region support the New Wars thesis: an increase in Islamist radicalization and new access to the global black market, both of which......, the paper finds that regimes in the Sahel region are still able to cope with the rise in non-state threats. The paper first shortly compares the longevity of the present regimes in the Sahel region to all previous ones, second examines in-depth how Chad and Mali fight the insurgents. Findings are that since...

  8. Proliferation: myth or reality?

    International Nuclear Information System (INIS)

    2005-01-01

    This article analyzes the proliferation approach, its technical condition and political motivation, and the share between the myth (political deception, assumptions and extrapolations) and the reality of proliferation. Its appreciation is complicated by the irrational behaviour of some political actors and by the significant loss of the non-use taboo. The control of technologies is an important element for proliferation slowing down but an efficient and autonomous intelligence system remains indispensable. (J.S.)

  9. Evaluation of toroidal torque by non-resonant magnetic perturbations in tokamaks for resonant transport regimes using a Hamiltonian approach

    Energy Technology Data Exchange (ETDEWEB)

    Albert, Christopher G.; Heyn, Martin F.; Kapper, Gernot; Kernbichler, Winfried; Martitsch, Andreas F. [Fusion@ÖAW, Institut für Theoretische Physik - Computational Physics, Technische Universität Graz, Petersgasse 16, 8010 Graz (Austria); Kasilov, Sergei V. [Fusion@ÖAW, Institut für Theoretische Physik - Computational Physics, Technische Universität Graz, Petersgasse 16, 8010 Graz (Austria); Institute of Plasma Physics, National Science Center “Kharkov Institute of Physics and Technology,” ul. Akademicheskaya 1, 61108 Kharkov (Ukraine)

    2016-08-15

    Toroidal torque generated by neoclassical viscosity caused by external non-resonant, non-axisymmetric perturbations has a significant influence on toroidal plasma rotation in tokamaks. In this article, a derivation for the expressions of toroidal torque and radial transport in resonant regimes is provided within quasilinear theory in canonical action-angle variables. The proposed approach treats all low-collisional quasilinear resonant neoclassical toroidal viscosity regimes including superbanana-plateau and drift-orbit resonances in a unified way and allows for magnetic drift in all regimes. It is valid for perturbations on toroidally symmetric flux surfaces of the unperturbed equilibrium without specific assumptions on geometry or aspect ratio. The resulting expressions are shown to match the existing analytical results in the large aspect ratio limit. Numerical results from the newly developed code NEO-RT are compared to calculations by the quasilinear version of the code NEO-2 at low collisionalities. The importance of the magnetic shear term in the magnetic drift frequency and a significant effect of the magnetic drift on drift-orbit resonances are demonstrated.

  10. Non-canonical microRNAs miR-320 and miR-702 promote proliferation in Dgcr8-deficient embryonic stem cells

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Byeong-Moo [Department of Medicine/GI Unit, Massachusetts General Hospital, Boston, MA 02114 (United States); Department of Medicine, Harvard Medical School, Boston, MA 02115 (United States); Choi, Michael Y., E-mail: mchoi@partners.org [Department of Medicine/GI Unit, Massachusetts General Hospital, Boston, MA 02114 (United States); Department of Medicine, Harvard Medical School, Boston, MA 02115 (United States); Harvard Stem Cell Institute, Boston, MA 02114 (United States)

    2012-09-21

    Highlights: Black-Right-Pointing-Pointer Embryonic stem cells (ESCs) lacking non-canonical miRNAs proliferate slower. Black-Right-Pointing-Pointer miR-320 and miR-702 are two non-canonical miRNAs expressed in ESCs. Black-Right-Pointing-Pointer miR-320 and miR-702 promote proliferation of Dgcr8-deficient ESCs. Black-Right-Pointing-Pointer miR-320 targets p57 and helps to release Dgcr8-deficient ESCs from G1 arrest. Black-Right-Pointing-Pointer miR-702 targets p21 and helps to release Dgcr8-deficient ESCs from G1 arrest. -- Abstract: MicroRNAs are known to contribute significantly to stem cell phenotype by post-transcriptionally regulating gene expression. Most of our knowledge of microRNAs comes from the study of canonical microRNAs that require two sequential cleavages by the Drosha/Dgcr8 heterodimer and Dicer to generate mature products. In contrast, non-canonical microRNAs bypass the cleavage by the Drosha/Dgcr8 heterodimer within the nucleus but still require cytoplasmic cleavage by Dicer. The function of non-canonical microRNAs in embryonic stem cells (ESCs) remains obscure. It has been hypothesized that non-canonical microRNAs have important roles in ESCs based upon the phenotypes of ESC lines that lack these specific classes of microRNAs; Dicer-deficient ESCs lacking both canonical and non-canonical microRNAs have much more severe proliferation defect than Dgcr8-deficient ESCs lacking only canonical microRNAs. Using these cell lines, we identified two non-canonical microRNAs, miR-320 and miR-702, that promote proliferation of Dgcr8-deficient ESCs by releasing them from G1 arrest. This is accomplished by targeting the 3 Prime -untranslated regions of the cell cycle inhibitors p57 and p21 and thereby inhibiting their expression. This is the first report of the crucial role of non-canonical microRNAs in ESCs.

  11. Formation and release of non-extractable 14C-Dicamba residues in soil under sterile and non-sterile regimes

    International Nuclear Information System (INIS)

    Gevao, Bondi; Jones, Kevin C.; Semple, Kirk T.

    2005-01-01

    The role of native soil microorganisms in the formation and release of non-extractable 14 C-residues, previously treated with 14 C-Dicamba, was investigated to examine their significance to the longer-term environmental effects on non-extractable pesticide residues. A 90 d study compared the fate of Dicamba under sterile and non-sterile regimes. In addition, soils were aged for 30 d and repeatedly extracted with a 0.01 M CaCl 2 solution, to an extraction end point, to produce non-extractable residues. The extracted soil containing non-extractable residues was mixed with clean soil that had been freshly spiked with non-labeled Dicamba at 0.2 mg kg -1 to increase the bulk volume of the soil and stimulate microbial activity. Sub-samples were then introduced into microcosms to compare the extent of microbially facilitated release and mineralisation with release rates in sterile microcosms. The results show that microorganisms play a significant role in the formation and release of non-extractable Dicamba residues. The release of 14 C-activity in sterile microcosms was linked to physical mixing of the extracted soil with field soil prior to the beginning of the incubations. The released 14 C-activity may be further mineralized, reincorporated into humus, or taken up by plants or other soil inhabiting biota

  12. European community energy policy and non-proliferation

    International Nuclear Information System (INIS)

    Jacchia, E.

    1982-01-01

    The author discusses the lack of get-tough attitudes in political solutions of the proliferation threat but sees the recent scientific breakthrough in nuclear fusion as hope for a new political direction

  13. A Non-Proliferating Fuel Cycle: No Enrichment, Reprocessing or Accessible Spent Fuel - 12375

    Energy Technology Data Exchange (ETDEWEB)

    Parker, Frank L. [Vanderbilt University (United States)

    2012-07-01

    Current fuel cycles offer a number of opportunities for access to plutonium, opportunities to create highly enriched uranium and access highly radioactive wastes to create nuclear weapons and 'dirty' bombs. The non-proliferating fuel cycle however eliminates or reduces such opportunities and access by eliminating the mining, milling and enrichment of uranium. The non-proliferating fuel cycle also reduces the production of plutonium per unit of energy created, eliminates reprocessing and the separation of plutonium from the spent fuel and the creation of a stream of high-level waste. It further simplifies the search for land based deep geologic repositories and interim storage sites for spent fuel in the USA by disposing of the spent fuel in deep sub-seabed sediments after storing the spent fuel at U.S. Navy Nuclear Shipyards that have the space and all of the necessary equipment and security already in place. The non-proliferating fuel cycle also reduces transportation risks by utilizing barges for the collection of spent fuel and transport to the Navy shipyards and specially designed ships to take the spent fuel to designated disposal sites at sea and to dispose of them there in deep sub-seabed sediments. Disposal in the sub-seabed sediments practically eliminates human intrusion. Potential disposal sites include Great Meteor East and Southern Nares Abyssal Plain. Such sites then could easily become international disposal sites since they occur in the open ocean. It also reduces the level of human exposure in case of failure because of the large physical and chemical dilution and the elimination of a major pathway to man-seawater is not potable. Of course, the recovery of uranium from sea water and the disposal of spent fuel in sub-seabed sediments must be proven on an industrial scale. All other technologies are already operating on an industrial scale. If externalities, such as reduced terrorist threats, environmental damage (including embedded

  14. Proliferation after the Iraq war

    International Nuclear Information System (INIS)

    Daguzan, J.F.

    2004-09-01

    This article uses the Iraq war major event to analyze the approach used by the US to fight against proliferation. It questions the decision and analysis process which has led to the US-British intervention and analyzes the consequences of the war on the proliferation of other countries and on the expected perspectives. Finally, the future of proliferation itself is questioned: do we have to fear more threat or is the virtuous circle of non-proliferation well started? (J.S.)

  15. Export of nuclear equipment and materials and the non-proliferation of nuclear weapons

    International Nuclear Information System (INIS)

    Courteix, Simone.

    1977-01-01

    The problem of the non-proliferation of nuclear weapons is one of great concern today despite the entry into force in the early '70s of the NPT. To master civilian nuclear technology implies the ability to develop nuclear explosive devices; therefore in recent years contacts have strengthened between countries exporting nuclear equipment, specially in the frame of the 'London Club' so as to ensure that their exports will not result in disseminating nuclear weapons. (NEA) [fr

  16. Proliferation risks

    International Nuclear Information System (INIS)

    Carchon, R.

    1998-09-01

    The report gives an overview of different aspects related to safeguards of fissile materials. Existing treaties including the Non-Proliferation Treaty, and the Tlatelolco and the Rarotonga Treaties are discussed. An overview of safeguards systems for the control of fissile materials as well as the role of various authorities is given. An overall overview of proliferation risks, the physical protection of fissile materials and the trade in fissile materials is given. Finally, the status in problem countries and de facto nuclear weapon states is discussed

  17. Model-Based Calculations of the Probability of a Country's Nuclear Proliferation Decisions

    International Nuclear Information System (INIS)

    Li, Jun; Yim, Man-Sung; McNelis, David N.

    2007-01-01

    The first nuclear weapon was detonated in August 1945 over Japan to end World War II. During the past six decades, the majority of the world's countries have abstained from acquiring nuclear weapons. However, a number of countries have explored the nuclear weapons option, 23 in all. Among them, 14 countries have dropped their interest in nuclear weapons after initiating some efforts. And nine of them today possess nuclear weapons. These countries include the five nuclear weapons states - U.S., Russia, U.K., France, and China - and the four non- NPT member states - Israel, India, Pakistan, and North Korea. Many of these countries initially used civilian nuclear power technology development as a basis or cover for their military program. Recent proliferation incidents in Iraq, Iran, and North Korea brought the world together to pay much attention to nuclear nonproliferation. With the expected surge in the use of nuclear energy for power generation by developing countries, the world's nuclear nonproliferation regime needs to be better prepared for potential future challenges. For the world's nuclear nonproliferation regime to effectively cope with any future proliferation attempts, early detection of potentially proliferation-related activities is highly desirable. Early detection allows the international community to respond and take necessary actions - ideally using political and diplomatic influences without resorting to harsh measures such as sanctions or military actions. In this regard, a capability to quantitatively predict the chance of a country's nuclear proliferation intent or activities is of significant interest. There have been various efforts in the research community to understand the determinants of nuclear proliferation and develop quantitative tools to predict nuclear proliferation events. These efforts have shown that information about the political issues surrounding a country's security along with economic development data can be useful to

  18. Editorial: disarmament, non proliferation, confidence-building measures, armament control

    International Nuclear Information System (INIS)

    Soutou, Georges-Henri

    2015-01-01

    After having described the vicious circle existing between disarmament and security as it appeared before and during the first World War, the author deals with the specific case of nuclear disarmament as it was first addressed just after the Second World War, and was then not accepted by the Russians. He comments the political and strategical approach adopted by the Kennedy administration, notably within the context of severe crises (Berlin and Cuba). This resulted in the re-establishment of a relationship between war and policy as defined by Clausewitz, but based on a trilogy of three inseparable pairs: deterrence and armament control, armament control and non proliferation, armament control and confidence-building measures. The author shows that this trilogy has been somehow operating until the end of Cold War, and that nothing works anymore since the end of Cold War and of the bipolar world

  19. Fitting and forecasting coupled dark energy in the non-linear regime

    Energy Technology Data Exchange (ETDEWEB)

    Casas, Santiago; Amendola, Luca; Pettorino, Valeria; Vollmer, Adrian [Institut für Theoretische Physik, Ruprecht-Karls-Universität Heidelberg, Philosophenweg 16, Heidelberg, 69120 Germany (Germany); Baldi, Marco, E-mail: casas@thphys.uni-heidelberg.de, E-mail: l.amendola@thphys.uni-heidelberg.de, E-mail: mail@marcobaldi.it, E-mail: v.pettorino@thphys.uni-heidelberg.de, E-mail: vollmer@thphys.uni-heidelberg.de [Dipartimento di Fisica e Astronomia, Alma Mater Studiorum Università di Bologna, viale Berti Pichat, 6/2, Bologna, I-40127 Italy (Italy)

    2016-01-01

    We consider cosmological models in which dark matter feels a fifth force mediated by the dark energy scalar field, also known as coupled dark energy. Our interest resides in estimating forecasts for future surveys like Euclid when we take into account non-linear effects, relying on new fitting functions that reproduce the non-linear matter power spectrum obtained from N-body simulations. We obtain fitting functions for models in which the dark matter-dark energy coupling is constant. Their validity is demonstrated for all available simulations in the redshift range 0z=–1.6 and wave modes below 0k=1 h/Mpc. These fitting formulas can be used to test the predictions of the model in the non-linear regime without the need for additional computing-intensive N-body simulations. We then use these fitting functions to perform forecasts on the constraining power that future galaxy-redshift surveys like Euclid will have on the coupling parameter, using the Fisher matrix method for galaxy clustering (GC) and weak lensing (WL). We find that by using information in the non-linear power spectrum, and combining the GC and WL probes, we can constrain the dark matter-dark energy coupling constant squared, β{sup 2}, with precision smaller than 4% and all other cosmological parameters better than 1%, which is a considerable improvement of more than an order of magnitude compared to corresponding linear power spectrum forecasts with the same survey specifications.

  20. Fitting and forecasting coupled dark energy in the non-linear regime

    International Nuclear Information System (INIS)

    Casas, Santiago; Amendola, Luca; Pettorino, Valeria; Vollmer, Adrian; Baldi, Marco

    2016-01-01

    We consider cosmological models in which dark matter feels a fifth force mediated by the dark energy scalar field, also known as coupled dark energy. Our interest resides in estimating forecasts for future surveys like Euclid when we take into account non-linear effects, relying on new fitting functions that reproduce the non-linear matter power spectrum obtained from N-body simulations. We obtain fitting functions for models in which the dark matter-dark energy coupling is constant. Their validity is demonstrated for all available simulations in the redshift range 0z=–1.6 and wave modes below 0k=1 h/Mpc. These fitting formulas can be used to test the predictions of the model in the non-linear regime without the need for additional computing-intensive N-body simulations. We then use these fitting functions to perform forecasts on the constraining power that future galaxy-redshift surveys like Euclid will have on the coupling parameter, using the Fisher matrix method for galaxy clustering (GC) and weak lensing (WL). We find that by using information in the non-linear power spectrum, and combining the GC and WL probes, we can constrain the dark matter-dark energy coupling constant squared, β 2 , with precision smaller than 4% and all other cosmological parameters better than 1%, which is a considerable improvement of more than an order of magnitude compared to corresponding linear power spectrum forecasts with the same survey specifications

  1. Morphology of silver deposits produced by non-stationary steady regimes

    International Nuclear Information System (INIS)

    Popovski, Orce

    2002-01-01

    Morphology of silver electro deposits produced by periodical reversing of d.c. pulses was studied. Employing usual electrorefining conditions it is not possible to deposit compact silver layers from Ag non-complexing salts. This is due, mainly, to the high value of silver exchange current density and to the silver crystallographic peculiarity. In order to counteract this phenomenon, instead of usual, (stationer) potential-current regimes, non-stationary one was applied in this study. The effect of phosphate ions in the electrolyte was further clarified. A set of experimental conditions was applied so that silver was electrodeposited under mixed electrochemical and diffusion control. The primar cathodic pulse causes silver to nucleate with high density and nuclei to start to grow. The subsequent anodic pulse (current reversal) lowers the gradient of silver ion concentration and dissolves the most active growth centers as well. The combination of cathodic and anodic pulses diminishes the dendritic growth and helps smoothing of deposit surface to occur. Fine-grained and more compact deposits are produced, as compared to the ones grown in purely potentiostatic conditions. It was found that the addition of phosphate ions as well as the application of intensive electrolyte stirring change the Ag- grain morphology in favor of poli crystal whisker structure. (Author)

  2. Verifying compliance with nuclear non-proliferation undertakings: IAEA safeguards agreements and additional protocols

    International Nuclear Information System (INIS)

    2008-06-01

    This report provides background information on safeguards and explains procedures for States to conclude Additional Protocols to comprehensive Safeguards Agreements with the IAEA. Since the IAEA was founded in 1957, its safeguards system has been an indispensable component of the nuclear non-proliferation regime and has facilitated peaceful nuclear cooperation. In recognition of this, the Treaty on the Non-Proliferation of Nuclear Weapons (NPT) makes it mandatory for all non-nuclear-weapon States (NNWS) party to the Treaty to conclude comprehensive safeguards agreements with the IAEA, and thus allow for the application of safeguards to all their nuclear material. Under Article III of the NPT, all NNWS undertake to accept safeguards, as set forth in agreements to be negotiated and concluded with the IAEA, for the exclusive purpose of verification of the fulfilment of the States' obligations under the NPT. In May 1997, the IAEA Board of Governors approved the Model Additional Protocol to Safeguards Agreements (reproduced in INFCIRC/540(Corr.)) which provided for an additional legal authority. In States that have both a comprehensive safeguards agreement and an additional protocol in force, the IAEA is able to optimize the implementation of all safeguards measures available. In order to simplify certain procedures under comprehensive safeguards agreements for States with little or no nuclear material and no nuclear material in a facility, the IAEA began making available, in 1971, a 'small quantities protocol' (SQP), which held in abeyance the implementation of most of the detailed provisions of comprehensive safeguards agreements for so long as the State concerned satisfied these criteria. The safeguards system aims at detecting and deterring the diversion of nuclear material. Such material includes enriched uranium, plutonium and uranium-233, which could be used directly in nuclear weapons. It also includes natural uranium and depleted uranium, the latter of which is

  3. Verifying compliance with nuclear non-proliferation undertakings: IAEA safeguards agreements and additional protocols

    International Nuclear Information System (INIS)

    2008-04-01

    This report provides background information on safeguards and explains procedures for States to conclude Additional Protocols to comprehensive Safeguards Agreements with the IAEA. Since the IAEA was founded in 1957, its safeguards system has been an indispensable component of the nuclear non-proliferation regime and has facilitated peaceful nuclear cooperation. In recognition of this, the Treaty on the Non-Proliferation of Nuclear Weapons (NPT) makes it mandatory for all non-nuclear-weapon States (NNWS) party to the Treaty to conclude comprehensive safeguards agreements with the IAEA, and thus allow for the application of safeguards to all their nuclear material. Under Article III of the NPT, all NNWS undertake to accept safeguards, as set forth in agreements to be negotiated and concluded with the IAEA, for the exclusive purpose of verification of the fulfilment of the States' obligations under the NPT. In May 1997, the IAEA Board of Governors approved the Model Additional Protocol to Safeguards Agreements (reproduced in INFCIRC/540(Corr.)) which provided for an additional legal authority. In States that have both a comprehensive safeguards agreement and an additional protocol in force, the IAEA is able to optimize the implementation of all safeguards measures available. In order to simplify certain procedures under comprehensive safeguards agreements for States with little or no nuclear material and no nuclear material in a facility, the IAEA began making available, in 1971, a 'small quantities protocol' (SQP), which held in abeyance the implementation of most of the detailed provisions of comprehensive safeguards agreements for so long as the State concerned satisfied these criteria. The safeguards system aims at detecting and deterring the diversion of nuclear material. Such material includes enriched uranium, plutonium and uranium-233, which could be used directly in nuclear weapons. It also includes natural uranium and depleted uranium, the latter of which is

  4. Dynamics of proliferating powers. For a new interdisciplinary approach

    International Nuclear Information System (INIS)

    Archambault, Jean-Claude; GRAND, Camille; Pasco, Xavier; SITT, Bernard

    2002-01-01

    The authors highlight that conventional approaches to the proliferation of arms of massive destruction are not sufficient to provide a generic evaluation grid whereas such a grid is clearly needed. In a first part, they discuss the contribution of various theories of proliferation of arms of massive destruction which generally address this phenomenon through three main points of view: legal and political means of struggle against proliferation, analysis of technical capacities, and motivations of proliferating States. The authors indicate and briefly present the various associated models. Then, they develop the basis of an analytical method aimed at a better understanding of the 'proliferating power', and at using various approaches, and notably that related to leader's psychology. They comment the content of studies already published on these issues, more precisely address the psycho-sociological dimension, outline the interest of diplomacy in this psychological approach, evoke the different typologies of personality, and propose elements of a new matrix of analysis of the proliferation phenomenon which takes national resources, history and strategic context, type of political regime, history and personality typology of the leader, and international dependencies, alliances, elites and mediators of the inner power, and public opinions into account

  5. Recommendations for strengthening the national systems and the international regime for combating of illicit trafficking. Keynote address/session 10

    International Nuclear Information System (INIS)

    Ek, P.; Wredberg, L.

    2001-01-01

    internal control, quality assurance, security culture and individual responsibilities; Shortage of suitable and modern equipment for monitoring and detection of radioactive material; Shortage of staff and training capabilities and insufficient financial resources concerning supervision and law enforcement authorities; Insufficient access to relevant information and data bases. A first step to improve national systems would be to assist states, by educating key-persons and authority staff, how to establish good, state-of-the-art national systems for combating of illicit trafficking, which would meet the requirements of international legal instruments, recommendations and guidelines. State Governments need to be made more aware of the seriousness of the proliferation threat and be convinced that supervision and law enforcement resources must be reinforced for bringing their national systems up to international standard. On the international level, combating of illicit trafficking would be ameliorated by improving the communication links between national authorities bi-laterally and with the international organisations. Also increased information exchange between national and international databases would improve prevention and detection capabilities. For the effective and consequent combating of illicit trafficking of nuclear material and equipment, it is, however, necessary that the international non-proliferation regime be strengthened through new initiatives and approaches. These should focus on, inter alia, a set of minimum requirements to be implemented, and to pursue, impose, follow-up and audit the implementation of those requirements into the national systems for combating of illicit trafficking. The IAEA is the recognised international organisation, both for nuclear energy promoting activities, and for the implementation of the international non-proliferation regime. The IAEA has, within its area of competence, relevant know-how and capability, including qualified

  6. Implementing nuclear non-proliferation in Finland. Regulatory control, international cooperation and the Comprehensive Nuclear-Test-Ban Treaty. Annual report 2011

    Energy Technology Data Exchange (ETDEWEB)

    Okko, O [ed.

    2012-07-01

    The regulatory control of nuclear materials (i.e. nuclear safeguards) is a prerequisite for the peaceful use of nuclear energy in Finland. Safeguards are required for Finland to comply with international agreements on nuclear non-proliferation - mainly the Non-Proliferation Treaty (NPT). This regulatory control is exercised by the Nuclear Materials Section of the Finnish Radiation and Nuclear Safety Authority (STUK). The results of STUK's nuclear safeguards inspection activities in 2011 continued to demonstrate that the Finnish licence holders take good care of their nuclear materials. There were no indications of undeclared nuclear materials or activities and the inspected materials and activities were in accordance with the licence holders' declarations.

  7. Measuring the effectiveness of international environmental regimes

    Energy Technology Data Exchange (ETDEWEB)

    Helm, C.; Sprinz, D.F.

    1999-05-01

    While past research has emphasized the importance of international regimes for international governance, systematic assessments of regime effects are missing. This article derives a standardized measurement concept for the effectiveness of international environmental regimes by developing an operational rational choice calculus to evaluate actual policy simultaneously against a non-regime counterfactual and a collective optimum. Subsequently, the empirical feasibility of the measurement instrument is demonstrated by way of two international treaties regulating transboundary air pollution in Europe. The results demonstrate that the regimes indeed show positive effects - but fall substantially short of the collective optima. (orig.)

  8. Security Guarantees and Nuclear Non-Proliferation

    International Nuclear Information System (INIS)

    Bruno Tertrais

    2011-01-01

    The purpose of this paper is to discuss the value of 'security guarantees', that is, positive security assurances that include a formal or informal defense commitment, in preventing nuclear proliferation. It demonstrates that such guarantees have proven to be a very effective instrument in preventing States from going nuclear. It would thus seem logical to reinforce or extend them. However, this path is fraught with obstacles and dilemmas

  9. Security Guarantees and Nuclear Non-Proliferation

    Energy Technology Data Exchange (ETDEWEB)

    Bruno Tertrais

    2011-07-01

    The purpose of this paper is to discuss the value of 'security guarantees', that is, positive security assurances that include a formal or informal defense commitment, in preventing nuclear proliferation. It demonstrates that such guarantees have proven to be a very effective instrument in preventing States from going nuclear. It would thus seem logical to reinforce or extend them. However, this path is fraught with obstacles and dilemmas

  10. TC-1 Overexpression Promotes Cell Proliferation in Human Non-Small Cell Lung Cancer that Can Be Inhibited by PD173074

    Science.gov (United States)

    Zhang, Na; Bai, Guangzhen; Zhong, Daixing; Su, Kai; Liu, Boya; Li, Xiaofei; Wang, Yunjie; Wang, Xiaoping

    2014-01-01

    Thyroid cancer-1 (TC-1), a natively disordered protein, is widely expressed in vertebrates and overexpressed in many kinds of tumors. However, its exact role and regulation mechanism in human non-small cell lung cancer (NSCLC) are still unclear. In the present study, we found that TC-1 is highly expressed in NSCLC and that its aberrant expression is strongly associated with NSCLC cell proliferation. Exogenous TC-1 overexpression promotes cell proliferation, accelerates the cell G1-to-S-phase transition, and reduces apoptosis in NSCLC. The knockdown of TC-1, however, inhibits NSCLC cell proliferation, cycle transition, and apoptosis resistance. Furthermore, we also demonstrated that PD173074, which functions as an inhibitor of the TC-1 in NSCLC, decreases the expression of TC-1 and inhibits TC-1 overexpression mediated cell proliferation in vitro and in vivo. Nevertheless, the inhibition function of PD173074 on NSCLC cell proliferation was eliminated in cells with TC-1 knockdown. These results suggest that PD173074 plays a significant role in TC-1 overexpression mediated NSCLC cell proliferation and may be a potential intervention target for the prevention of cell proliferation in NSCLC. PMID:24941347

  11. Russia and proliferation in Northeast Asia

    International Nuclear Information System (INIS)

    Ignatov, A.I.

    1995-01-01

    For Russia, security, including non-proliferation, in Northeast Asia means in particular the maintenance of stability. Progress in arms control and non-proliferation may enhance regional stability. A common regional approach is proposed. Russia recognizes the US alliances with Japan and republic of Korea and is searching for a new cooperation framework in the region, namely further development of relations with China and reasonable rapprochement with Japan

  12. The nuclear non-proliferation: The validity of the rule in Latin America

    International Nuclear Information System (INIS)

    Cubillos Meza, Adela

    2005-01-01

    The position of Latin American countries within the framework of the Non Nuclear Proliferation Treaty NPT is analyzed in this article. This treaty which entered into force in 1968, has been ratified by a significant number of countries. The nuclear- weapon states, the United States and the former USSR gave origin to the NPT in order to control nuclear proliferation. This treaty has been subject to criticism since it discriminates between the countries which have nuclear weapons and the ones that do not. Thus, the former are allowed to manufacture atomic devices, but it has been forbidden for the latter. Even nuclear- weapon states such as France and China did not support the treaty immediately because they consider it as highly discriminatory. Countries that do not have nuclear weapons have criticized the NPT and did not joined immediately. Among these parties, we can mention three Latin American countries, Argentina, Brazil and Chile. The first two only signed the NPT when they were fully capable and autonomous in nuclear power. The Chilean position of not joining immediately depended upon the Argentinian and Brazilian decision [es

  13. Treaty on the Non-Proliferation of Nuclear Weapons. Notification of the Entry into Force

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1970-04-22

    By letters addressed to the Director General on 5, 6 and 20 March 1970 respectively, the Governments of the United Kingdom of Great Britain and Northern Ireland, the United States of America and the Union of Soviet Socialist Republics, which are designated as the Depository Governments in Article IX. 2 of the Treaty on the Non-Proliferation of Nuclear Weapons, informed the Agency that the Treaty had entered into force on 5 March 1970.

  14. Treaty on the Non-Proliferation of Nuclear Weapons. Notification of the Entry into Force

    International Nuclear Information System (INIS)

    1970-01-01

    By letters addressed to the Director General on 5, 6 and 20 March 1970 respectively, the Governments of the United Kingdom of Great Britain and Northern Ireland, the United States of America and the Union of Soviet Socialist Republics, which are designated as the Depository Governments in Article IX. 2 of the Treaty on the Non-Proliferation of Nuclear Weapons, informed the Agency that the Treaty had entered into force on 5 March 1970

  15. Treaty on the Non-Proliferation of Nuclear Weapons. Notification of the Entry into Force

    International Nuclear Information System (INIS)

    1970-01-01

    By letters addressed to the Director General on 5, 6 and 20 March 1970 respectively, the Governments of the United Kingdom of Great Britain and Northern Ireland, the United States of America and the Union of Soviet Socialist Republics, which are designated as the Depository Governments in Article IX. 2 of the Treaty on the Non-Proliferation of Nuclear Weapons, informed the Agency that the Treaty had entered into force on 5 March 1970 [fr

  16. Treaty on the Non-Proliferation of Nuclear Weapons. Notification of the Entry into Force

    International Nuclear Information System (INIS)

    1986-10-01

    By letters addressed to the Director General on 5, 6 and 20 March 1970 respectively, the Governments of the United Kingdom of Great Britain and Northern Ireland, the United States of America and the Union of Soviet Socialist Republics, which are designated as the Depository Governments in Article IX. 2 of the Treaty on the Non-Proliferation of Nuclear Weapons, informed the Agency that the Treaty had entered into force on 5 March 1970

  17. Treaty on the Non-Proliferation of Nuclear Weapons. Notification of the Entry into Force

    International Nuclear Information System (INIS)

    1970-01-01

    By letters addressed to the Director General on 5, 6 and 20 March 1970 respectively, the Governments of the United Kingdom of Great Britain and Northern Ireland, the United States of America and the Union of Soviet Socialist Republics, which are designated as the Depositary Governments in Article IX. 2 of the Treaty on the Non-Proliferation of Nuclear Weapons, informed the Agency that the Treaty had entered into force on 5 March 1970 [ru

  18. Treaty on the Non-Proliferation of Nuclear Weapons. Notification of the Entry into Force

    International Nuclear Information System (INIS)

    1970-01-01

    By letters addressed to the Director General on 5, 6 and 20 March 1970 respectively, the Governments of the United Kingdom of Great Britain and Northern Ireland, the United States of America and the Union of Soviet Socialist Republics, which are designated as the Depository Governments in Article IX. 2 of the Treaty on the Non-Proliferation of Nuclear Weapons, informed the Agency that the Treaty had entered into force on 5 March 1970 [es

  19. Treaty on the Non-Proliferation of Nuclear Weapons. Notification of the Entry into Force

    International Nuclear Information System (INIS)

    1970-04-01

    By letters addressed to the Director General on 5, 6 and 20 March 1970 respectively, the Governments of the United Kingdom of Great Britain and Northern Ireland, the United States of America and the Union of Soviet Socialist Republics, which are designated as the Depository Governments in Article IX. 2 of the Treaty on the Non-Proliferation of Nuclear Weapons, informed the Agency that the Treaty had entered into force on 5 March 1970

  20. The fight against weapons of mass destruction at the crossroads

    International Nuclear Information System (INIS)

    Biad, A.

    2004-01-01

    Under the joint pressure of the US unilateralism and of some proliferating countries, the non-proliferation regimes are today at the crossroads. Despite the enormous efforts mobilized so far, the proliferation of weapons of mass destruction appears as inescapable. This article analyzes the reasons of the continuous erosion of non-proliferation regimes and the possible means to delay this phenomenon: counter-proliferation measures, control of exported nuclear technologies and equipments, use of diplomatic and politico-economical means, controlled multilateral disarmament. (J.S.)

  1. In vitro proliferation of adult human beta-cells.

    Directory of Open Access Journals (Sweden)

    Sabine Rutti

    Full Text Available A decrease in functional beta-cell mass is a key feature of type 2 diabetes. Glucagon-like peptide 1 (GLP-1 analogues induce proliferation of rodent beta-cells. However, the proliferative capacity of human beta-cells and its modulation by GLP-1 analogues remain to be fully investigated. We therefore sought to quantify adult human beta-cell proliferation in vitro and whether this is affected by the GLP-1 analogue liraglutide.Human islets from 7 adult cadaveric organ donors were dispersed into single cells. Beta-cells were purified by FACS. Non-sorted cells and the beta-cell enriched ("beta-cells" population were plated on extracellular matrix from rat (804G and human bladder carcinoma cells (HTB9 or bovine corneal endothelial ECM (BCEC. Cells were maintained in culture+/-liraglutide for 4 days in the presence of BrdU.Rare human beta-cell proliferation could be observed either in the purified beta-cell population (0.051±0.020%; 22 beta-cells proliferating out of 84'283 beta-cells counted or in the non-sorted cell population (0.055±0.011%; 104 proliferating beta-cells out of 232'826 beta-cells counted, independently of the matrix or the culture conditions. Liraglutide increased human beta-cell proliferation on BCEC in the non-sorted cell population (0.082±0.034% proliferating beta-cells vs. 0.017±0.008% in control, p<0.05.These results indicate that adult human beta-cell proliferation can occur in vitro but remains an extremely rare event with these donors and particular culture conditions. Liraglutide increases beta-cell proliferation only in the non-sorted cell population and only on BCEC. However, it cannot be excluded that human beta-cells may proliferate to a greater extent in situ in response to natural stimuli.

  2. Ionospheric measurements for the Non-Proliferation Experiment

    International Nuclear Information System (INIS)

    Fitzgerald, T.J.

    1994-01-01

    The detection of explosions using ionospheric techniques relies on measuring perturbations induced in radio propagation by acoustics waves which disturb the electron density of the ionosphere. Such techniques have been applied to the detection of atmospheric explosions, underground nuclear tests, earthquakes, and surface mining explosions. The nighttime ionosphere presents a difficulty for the detection of explosions because in the absence of solar ionization radiation the electron density in the altitude range of 90 to 200 km decays after sunset and perturbation effects are correspondingly reduced. On the other hand, acoustic waves produced by weak sources reach a maximum amplitude in the altitude range of 100 to 150 km and are highly attenuated at altitudes above 200 km. For safety reasons, most planned explosions are conducted during daylight which has limited the experimental measurements during nighttime. However a recent opportunity for a nighttime measurement occurred in connection with the Non-Proliferation Experiment which consisted of the detonation of a large chemical charge underground at the Nevada Test Site near midnight local time. the results, based on a new technique of using medium frequency radio transmissions provided by commercial broadcasts to detect explosion effects, were negative. The most likely explanation for the negative result is that the radio transmissions did not reflect at a low enough altitude to sense the perturbations produced by the acoustic waves

  3. Loschmidt echo for local perturbations: non-monotonic cross-over from the Fermi-golden-rule to the escape-rate regime

    International Nuclear Information System (INIS)

    Goussev, Arseni; Waltner, Daniel; Richter, Klaus; Jalabert, Rodolfo A

    2008-01-01

    We address the sensitivity of quantum mechanical time evolution by considering the time decay of the Loschmidt echo (LE) (or fidelity) for local perturbations of the Hamiltonian. Within a semiclassical approach, we derive analytical expressions for the LE decay for chaotic systems for the whole range from weak to strong local perturbations and identify different decay regimes which complement those known for the case of global perturbations. For weak perturbations, a Fermi-golden-rule (FGR)-type behavior is recovered. For strong perturbations, the escape-rate regime is reached, where the LE decays exponentially with a rate independent of the perturbation strength. The transition between the FGR regime and the escape-rate regime is non-monotonic, i.e. the rate of the exponential time-decay of the LE oscillates as a function of the perturbation strength. We further perform extensive quantum mechanical calculations of the LE based on numerical wave packet evolution, which strongly support our semiclassical theory. Finally, we discuss in some detail possible experimental realizations for observing the predicted behavior of the LE

  4. Serratia marcescens Is Able to Survive and Proliferate in Autophagic-Like Vacuoles inside Non-Phagocytic Cells

    Science.gov (United States)

    Colombo, María Isabel; García Véscovi, Eleonora

    2011-01-01

    Serratia marcescens is an opportunistic human pathogen that represents a growing problem for public health, particularly in hospitalized or immunocompromised patients. However, little is known about factors and mechanisms that contribute to S. marcescens pathogenesis within its host. In this work, we explore the invasion process of this opportunistic pathogen to epithelial cells. We demonstrate that once internalized, Serratia is able not only to persist but also to multiply inside a large membrane-bound compartment. This structure displays autophagic-like features, acquiring LC3 and Rab7, markers described to be recruited throughout the progression of antibacterial autophagy. The majority of the autophagic-like vacuoles in which Serratia resides and proliferates are non-acidic and have no degradative properties, indicating that the bacteria are capable to either delay or prevent fusion with lysosomal compartments, altering the expected progression of autophagosome maturation. In addition, our results demonstrate that Serratia triggers a non-canonical autophagic process before internalization. These findings reveal that S. marcescens is able to manipulate the autophagic traffic, generating a suitable niche for survival and proliferation inside the host cell. PMID:21901159

  5. Assuring the success of the non-proliferation treaty extension conference. Excerpts from the panel discussions

    International Nuclear Information System (INIS)

    1994-01-01

    This publication presents excerpts from a conference organized by the NGO Committee on Disarmament Inc., in cooperation with the United Nations Centre for Disarmament Affairs, and covers the following issues: status of the comprehensive test ban treaty negotiations, fissile cut-off and ending production of nuclear weapons, how should nuclear weapons states pursue disarmament under Non-Proliferation Treaty (NPT), NPT extension: problems and prospects

  6. Review and comment on the advanced spent fuel management process (1): Technical aspects and non-proliferation concerns

    International Nuclear Information System (INIS)

    Song, Yo Taik

    2001-01-01

    Efforts are made to analyze the project, the Advanced Spent Fuel Management Technology (ASFMT), which is currently carried out at Korea Atomic Energy Research Institute, on the technical feasibility and validity as well as on the nuclear non-proliferation concerns. The project is a part of a program under the 'Long and Midterm Nuclear Development Program'. On the technical analysis, reviewed the papers presented at the national and international meetings on the subject by KAERI staffs, and also participated to various technical discussions on the 'Mock-up Test', currently in progress. On the non-proliferation concerns, the ASFMT project was reviewed and analyzed in reference to various programs currently in progress or in a formulation stages in US, such as the DOE TOPS and ATW. Further reviewed the past JASNEC process and programs for possible application of the ASFMT project for JASNEC project. Provided a few thoughts for effectively carrying out the ASFMT project, and a plan for the next phase is presented

  7. Review and comment on the advanced spent fuel management process (1): Technical aspects and non-proliferation concerns

    Energy Technology Data Exchange (ETDEWEB)

    Song, Yo Taik

    2001-01-01

    Efforts are made to analyze the project, the Advanced Spent Fuel Management Technology (ASFMT), which is currently carried out at Korea Atomic Energy Research Institute, on the technical feasibility and validity as well as on the nuclear non-proliferation concerns. The project is a part of a program under the 'Long and Midterm Nuclear Development Program'. On the technical analysis, reviewed the papers presented at the national and international meetings on the subject by KAERI staffs, and also participated to various technical discussions on the 'Mock-up Test', currently in progress. On the non-proliferation concerns, the ASFMT project was reviewed and analyzed in reference to various programs currently in progress or in a formulation stages in US, such as the DOE TOPS and ATW. Further reviewed the past JASNEC process and programs for possible application of the ASFMT project for JASNEC project. Provided a few thoughts for effectively carrying out the ASFMT project, and a plan for the next phase is presented.

  8. Implementing nuclear non-proliferation in Finland. Regulatory control, international cooperation and the Comprehensive Nuclear-Test-Ban Treaty. Annual report 2011

    Energy Technology Data Exchange (ETDEWEB)

    Okko, O. (ed.)

    2012-07-01

    The regulatory control of nuclear materials (i.e. nuclear safeguards) is a prerequisite for the peaceful use of nuclear energy in Finland. Safeguards are required for Finland to comply with international agreements on nuclear non-proliferation - mainly the Non-Proliferation Treaty (NPT). This regulatory control is exercised by the Nuclear Materials Section of the Finnish Radiation and Nuclear Safety Authority (STUK). The results of STUK's nuclear safeguards inspection activities in 2011 continued to demonstrate that the Finnish licence holders take good care of their nuclear materials. There were no indications of undeclared nuclear materials or activities and the inspected materials and activities were in accordance with the licence holders' declarations.

  9. Anti-neutrino flux in a research reactor for non-proliferation application

    Energy Technology Data Exchange (ETDEWEB)

    Khakshournia, Samad; Foroughi, Shokoufeh [Nuclear Science and Technology Research Institute (NSTRI), Tehran (Iran, Islamic Republic of). Atomic Energy Organization of Iran (AEOI)

    2017-11-15

    Owing to growing interest in the study of emitted antineutrinos from nuclear reactors to test the Atomic Energy Agency safeguards, antineutrino flux was studied in the Tehran Research Reactor (TRR) using ORIGEN code. According to our prediction, antineutrino rate was obtained 2.6 x 10{sup 17} (v{sub e}/sec) in the core No. 57F of the TRR. Calculations indicated that evolution of antineutrino flux was very slow with time and the performed refueling had not an observable effect on antineutrino flux curve for a 5 MW reactor with the conventional refueling program. It is seen that for non-proliferation applications the measurement of the contribution of {sup 239}Pu to the fission using an antineutrino detector is not viable in the TRR.

  10. Nuclear power the challenges of non-proliferation

    International Nuclear Information System (INIS)

    Anon.

    2010-01-01

    The revival of the civil nuclear power industry rekindles the debate on proliferation, in other words, on the increase in the number of States likely to achieve nuclear weapon capability. The history of the past thirty years shows that none of the known attempts at proliferation has occurred within the scope of civil nuclear program development. No country that has decided to 'proliferate' has done so by diverting materials or installations governed by the commitment to peaceful utilization and under IAEA control. The only borderline case is India, which did not sign the NPT, and which in 1974 cleverly played on the clauses imposed on it by Canada without violating them in the strictest sense of the word. The exporters of civil nuclear technologies subsequently got organized to control the export of sensitive materials by creating the Club of London, since renamed the Nuclear Suppliers Group. Another crisis occurred in 1991 following the first Gulf war, with the discovery of an extensive covert nuclear program in Iraq (an NPT signatory country); this caused a shock similar to that of 1974 and resulted in the strengthening of the IAEA's powers and inspection resources. India subsequently carried out several nuclear tests in 1998, at least one of which was a thermonuclear device. Pakistan, India's rival since the 1948 partition, crossed the 'nuclear threshold' in 1999. Proliferation also made headlines in 2003. First of all with Libya which, having decided to sign the NPT, revealed the existence of what is called the 'Nuke AQ Khan Bazaar'. In the presumed ignorance of his government, Dr. Abdul Qadeer Khan had stolen an uranium enrichment technology, becoming the 'father' of the Pakistani bomb, and had organized the traffic of military nuclear technologies, namely with Libya, North Korea and Iran. Again in 2003, North Korea announced its withdrawal from the NPT. This retreat raises the question of what will become of the possible transfers of nuclear technologies that

  11. Wnt3a regulates proliferation and migration of HUVEC via canonical and non-canonical Wnt signaling pathways

    International Nuclear Information System (INIS)

    Samarzija, Ivana; Sini, Patrizia; Schlange, Thomas; MacDonald, Gwen; Hynes, Nancy E.

    2009-01-01

    Untangling the signaling pathways involved in endothelial cell biology is of central interest for the development of antiangiogenesis based therapies. Here we report that Wnt3a induces the proliferation and migration of HUVECs, but does not affect their survival. Wnt3a-induced proliferation was VEGFR signaling independent, but reduced upon CamKII inhibition. In a search for the downstream mediators of Wnt3a's effects on HUVEC biology, we found that Wnt3a treatment leads to phosphorylation of DVL3 and stabilization of β-catenin. Moreover, under the same conditions we observed an upregulation in c-MYC, TIE-2 and GJA1 mRNA transcripts. Although treatment of HUVECs with Wnt5a induced DVL3 phosphorylation, we did not observe any of the other effects seen upon Wnt3a stimulation. Taken together, our data indicate that Wnt3a induces canonical and non-canonical Wnt signaling in HUVECs, and stimulates their proliferation and migration.

  12. Nuclear non-proliferation: The security context, 5 October 2007, University of Florence, Florence, Italy

    International Nuclear Information System (INIS)

    ElBaradei, M.

    2007-01-01

    Dr. Mohamed ElBaradei, Director General of the International Atomic Energy Agency, stated that nuclear threats have become more dangerous and more complex. We have witnessed the emergence of illicit trade in nuclear technology. Countries have managed to develop clandestine nuclear programmes. Sophisticated extremist groups have shown keen interest in acquiring nuclear weapons. n parallel, nuclear material and nuclear material production have become more difficult to control. Energy security concerns and fears of climate change are prompting many countries to revisit the nuclear power option. And to ensure a supply of reactor fuel, more countries have shown interest in mastering the nuclear fuel cycle - a step that brings them quite close to nuclear weapons capability. Add to this the 27 000 nuclear warheads that already exist in the arsenals of nine countries, and the hair trigger alert deployment level of some of these weapons. And as if these stockpiles and their deployment were not threat enough, most of these countries continue to repeat two inherently contradictory mantras: first, that it is important for them to continue to rely on nuclear weapons for their security; and second, that no one else should have them. 'Do as I say, not as I do'. Against this backdrop, there are four critical aspects of the nuclear non-proliferation regime that we must strengthen - addressing both symptoms and root causes - if we are to avoid a cascade of nuclear proliferation, and our ultimate self-destruction. First, we must develop a more effective approach for dealing with proliferation threats. Second, we must secure existing nuclear material stockpiles and tighten controls over the transfer and production of nuclear material. Third, we must strengthen the verification authority and capability of the IAEA. Fourth, we urgently need to find a way for disarmament to be given the prominence and priority it deserves. In conclusion, it is clear that a security strategy rooted in 'Us

  13. The G1/S Specific Cyclin D2 Is a Regulator of HIV-1 Restriction in Non-proliferating Cells

    Science.gov (United States)

    Badia, Roger; Pujantell, Maria; Riveira-Muñoz, Eva; Puig, Teresa; Torres-Torronteras, Javier; Martí, Ramón; Clotet, Bonaventura; Ampudia, Rosa M.; Ballana, Ester

    2016-01-01

    Macrophages are a heterogeneous cell population strongly influenced by differentiation stimuli that become susceptible to HIV-1 infection after inactivation of the restriction factor SAMHD1 by cyclin-dependent kinases (CDK). Here, we have used primary human monocyte-derived macrophages differentiated through different stimuli to evaluate macrophage heterogeneity on cell activation and proliferation and susceptibility to HIV-1 infection. Stimulation of monocytes with GM-CSF induces a non-proliferating macrophage population highly restrictive to HIV-1 infection, characterized by the upregulation of the G1/S-specific cyclin D2, known to control early steps of cell cycle progression. Knockdown of cyclin D2, enhances HIV-1 replication in GM-CSF macrophages through inactivation of SAMHD1 restriction factor by phosphorylation. Co-immunoprecipitation experiments show that cyclin D2 forms a complex with CDK4 and p21, a factor known to restrict HIV-1 replication by affecting the function of the downstream cascade that leads to SAMHD1 deactivation. Thus, we demonstrate that cyclin D2 acts as regulator of cell cycle proteins affecting SAMHD1-mediated HIV-1 restriction in non-proliferating macrophages. PMID:27541004

  14. Safety, Security, and Stability: The Role of Nuclear Control Regimes in a Proliferated World

    National Research Council Canada - National Science Library

    Collins, James

    1995-01-01

    ... with developing and deploying nuclear weapons. The US, in the past, has refused to provide technical assistance to enhance the safety, security, and stability of proliferating countries' nuclear arsenals-we believe this policy...

  15. Trends in the proliferation of weapons of mass destruction

    International Nuclear Information System (INIS)

    Karp, A.

    1995-01-01

    Nuclear and missile proliferation are neither unique nor necessarily the most imposing proliferation challenges, but they are probably the most visible and mature aspects of the proliferation problem. In nuclear proliferation there the news are very ambivalent. Today we face somewhat between 7 and 9 counties with nuclear weapons: 5 acknowledged nuclear powers, Israel and Ukraine as well as the uncertain status of Pakistan and North Korea. The growing number of countries that have given up their nuclear programs is impressive, most spectacularly Argentina, Brazil and South Africa. Recently Kazakhstan has signed the Non-proliferation Treaty, and Belarus seems certain to follow. Thus the problem list is a short one now. The remaining issues are to be treated at the 1995 Non-proliferation Treaty Extension Conference

  16. The challenge of nuclear proliferation control in South Asia

    International Nuclear Information System (INIS)

    Mian, J.A.

    1996-01-01

    Prevention of nuclear weapon proliferation in South Asia is considered a a difficult challenge. The paper discusses the difficulties met in implementing the nuclear non-proliferation policy due to numerous disputes concerning China, North and South Korea, India and Pakistan, and the countries of former Soviet Union. Matters preventing proliferation are mentioned as well as obstacles to non-proliferation proposing that decisions whether voluntary or, eventually, compulsory would have to be consistently enforced by the Security Council, if states are to rely upon those methods for their security

  17. Geology, geophysics, and physical properties of the U12n.25 non-proliferation experiment site

    Energy Technology Data Exchange (ETDEWEB)

    Baldwin, M.J.; Bradford, R.P.; Hopkins, S.P. [Raytheon Services Nevada, Mercury, NV (United States)] [and others

    1994-12-31

    The Nuclear Non-Proliferation Experiment was conducted in the U12n.25 drift in N-Tunnel at the Nevada Test Site. The geologic characterization of the site was performed by Raytheon Services Nevada geologists in the standard manner used for all underground nuclear weapons-effects tests executed by the Defense Nuclear Agency. The U12n.25 test bed was constructed in zeolitized ash-fall tuff of the Tunnel Beds Tuff, Subunit 4K, 389.0 m below the surface of Rainier Mesa. The structural geology of the site was simple, with the nearest fault plane projected to be 12 m below the mined cavity at closest approach, and an average bedding dip of seven degrees to the northwest. The cavity excavation revealed several small fractures, including one which produced minor amounts of free water during construction. The physical properties of the site were well within the range of experience for the zeolitized tuff of N-Tunnel and no geology-related problems were encountered during construction. The zeolitized tuff of N-Tunnel has been the site of twenty nuclear tests conducted by the Defense Nuclear Agency. The similarities of geologic setting, site geometry, and physical properties allow many comparisons of Non-Proliferation Experiment results with the large nuclear-test data base.

  18. 1995 review and extension conference of the parties to the treaty on the non-proliferation of nuclear weapons

    International Nuclear Information System (INIS)

    1995-01-01

    On 19 July 1995, the Director General received a letter, addressed to him by the Alternate Resident Representative of Canada to the International Atomic Energy Agency, concerning 1995 review and extension conference of the parties to the treaty on the non-proliferation of nuclear weapons

  19. CISH has no non-redundant functions in glucose homeostasis or beta cell proliferation during pregnancy in mice.

    Science.gov (United States)

    Jiao, Yang; Rieck, Sebastian; Le Lay, John; Kaestner, Klaus H

    2013-11-01

    Increased beta cell proliferation during pregnancy is mediated by the Janus kinase 2/signal transducer and activator of transcription 5 (JAK2/STAT5) signalling pathway in response to increased lactogen levels. Activation of the pathway leads to transcriptional upregulation of Cish (encoding cytokine-inducible SH2 domain-containing protein), a member of the suppressor of cytokine signalling (SOCS) family of genes, forming a negative-feedback loop. Here, we examined whether conditional gene ablation of Cish in the pancreas improves beta cell proliferation and beta cell function during pregnancy in mice. We derived mice with a novel, conditional loxP allele for Cish. Pancreas-specific ablation of Cish was achieved by crossing Cish (loxP/loxP) mice with Pdx1-Cre (Early) mice. Beta cell proliferation was quantified by BrdU labelling. Glucose homeostasis was examined with glucose tolerance tests and determination of plasma insulin levels. The expression of other Socs genes and target genes of p-STAT5 related to beta cell function and beta cell proliferation was determined by quantitative PCR. There was no difference in beta cell proliferation or glucose homeostasis between the Cish mutant group and the control group. The p-STAT5 protein level was the same in Cish mutant and control mice. Socs2 gene expression was higher in Cish mutant than control mice at pregnancy day 9.5. The expression of other Socs genes was the same between control and mutant mice. Our results show that CISH has no non-redundant functions in beta cell proliferation or glucose homeostasis during pregnancy in mice. Socs2 might compensate for the loss of Cish during pregnancy.

  20. Placenta-specific protein 1 promotes cell proliferation and invasion in non-small cell lung cancer

    Science.gov (United States)

    Yang, Li; Zha, Tian-Qi; He, Xiang; Chen, Liang; Zhu, Quan; Wu, Wei-Bing; Nie, Feng-Qi; Wang, Qian; Zang, Chong-Shuang; Zhang, Mei-Ling; He, Jing; Li, Wei; Jiang, Wen; Lu, Kai-Hua

    2018-01-01

    Pulmonary carcinoma-associated proteins have emerged as crucial players in governing fundamental biological processes such as cell proliferation, apoptosis and metastasis in human cancers. Placenta-specific protein 1 (PLAC1) is a cancer-related protein, which is activated and upregulated in a variety of malignant tissues, including prostate cancer, gastric adenocarcinoma, colorectal, epithelial ovarian and breast cancer. However, its biological role and clinical significance in non-small cell lung cancer (NSCLC) development and progression are still unknown. In the present study, we found that PLAC1 was significantly upregulated in NSCLC tissues, and its expression level was associated with advanced pathological stage and it was also correlated with shorter progression-free survival of lung cancer patients. Furthermore, knockdown of PLAC1 expression by siRNA inhibited cell proliferation, induced apoptosis and impaired invasive ability in NSCLC cells partly via regulation of epithelial-mesenchymal transition (EMT)-related protein expression. Our findings present that increased PLAC1 could be identified as a negative prognostic biomarker in NSCLC and regulate cell proliferation and invasion. Thus, we conclusively demonstrated that PLAC1 plays a key role in NSCLC development and progression, which may provide novel insights on the function of tumor-related gene-driven tumorigenesis. PMID:29138842

  1. Effects of Monoclonal Antibody Cetuximab on Proliferation of Non-small Cell Lung Cancer Cell lines

    Directory of Open Access Journals (Sweden)

    Zhen CHEN

    2010-08-01

    Full Text Available Background and objective The epidermal growth factor receptor (EGFR monoclonal antibody cetuximab has been used widely in non-small cell lung cancer patients. The aim of this study is to explore the effect of lung cancer cells (A549, H460, H1299, SPC-A-1 which were treated by cetuximab in vitro. Methods We studied the effects of increasing concentrations of cetuximab (1 nmol/L-625 nmol/L in four human lung cancer cell lines (A549, SPC-A-1, H460, H1229. CCK8 measured the inhibition of cell proliferation in each group. A549, SPC-A-1 were marked by PI and the statuses of apoptosis were observed. Western blot were used to detect the proliferation-related signaling protein and apoptosis-related protein in A549. Results The treatment with cetuximab resulted in the effect on cell proliferation and apoptosis in a time- and dosedependent manner. The expression of activated key enzymes (p-AKT, p-EGFR, p-MAPK in EGFR signaling transduction pathway were down-regulated more obviously. Conclusion Cetuximab is an effective targeted drug in the treatment of lung cancer cell lines, tissues, most likely to contribute to the inhibition of key enzymes in EGFR signaling transduction pathway.

  2. Post-test geologic observations made at the non-proliferation experiment site, N-tunnel, Nevada Test Site

    Energy Technology Data Exchange (ETDEWEB)

    Townsend, D.R.; Bradford, R.P.; Hopkins, S.P. [Raytheon Services Nevada, Mercury, NV (United States)] [and others

    1994-12-31

    Qualitative evaluations of damage resulting from an underground explosion can provide valuable information concerning the size of the charge, as well as the location of a clandestine detonation. However, caution must be exercised during the appraisal because the effects of an explosion are a function of many factors in addition to yield. Construction techniques, the physical properties of the surrounding rock, and the depth of burial are all important considerations when evaluating the effects of an underground detonation. Raytheon Services Nevada geologists documented underground and surface effects of the Non-Proliferation Experiment, as they have for all recent underground weapons-effects tests conducted by the Defense Nuclear Agency. Underground, the extent of the visible damage decreased rapidly from severe at the closest inspection point 100 m from the Working Point, to insignificant 300 m from the Working Point. The severity of damage correlates in some instances with the orientation of the drift with respect to the shock-wave propagation direction. No evidence of the Non-Proliferation explosion was visible on the mesa surface 389 m above the Working Point the day after the explosion.

  3. Information report on the behalf of the foreign affairs, defence and armed forces Commission on France security, nuclear disarmament and non proliferation

    International Nuclear Information System (INIS)

    2010-01-01

    This report first gives an overview of nuclear disarmament and non proliferation twenty years after the end of Cold War: evolution and status of Russia's and United States' nuclear weapon arsenals, France's and United Kingdom's trend to reduce their nuclear armament, reinforcement of China's nuclear armament, effects and limitations of the Non Proliferation Treaty (NPT). It notices that the new international context gave birth to some expectations and may lead to a lower nuclear pressure, notably with the influence of START negotiations between Russia and the United States, provided that the Comprehensive Nuclear Test Ban Treaty is ratified by more countries, and that negotiations promote a Fissile Material Cut-off Treaty. The report also outlines the importance of the promotion of better controlled peaceful uses of nuclear energy. It discusses the relationship between maintaining the world nuclear order and the reduction of international and regional tensions, and the importance of struggle against all forms of proliferation. It analyses the French nuclear posture in terms of security requirements, and in front of the zero nuclear option, in a context of ballistic missile proliferation, and in relationship with the issue of tactical nuclear weapons in Europe

  4. Present status of the Treaty on the non-proliferation of nuclear weapons

    International Nuclear Information System (INIS)

    Netchaev, B.

    1976-01-01

    The Treaty for the Non-Proliferation of Nuclear Weapons plays an important role in enhancing the security of all States. It is essential to maintain in the implementation of the Treaty an acceptable balance of the mutual responsibilities and obligations of all the countries Party to the Treaty wether or not nuclear weapon States. These questions were discussed during the Conference on the operation of the Treaty held in Geneva in May 1975. It was emphasized at the Conference that the first five years of application of the Treaty had shown a consistent increase in the number of ratifications and in the safeguards agreements concluded on the basis of the Agreement. (N.E.A.) [fr

  5. Nuclear power and nuclear weapons proliferation

    International Nuclear Information System (INIS)

    Anon.

    1978-01-01

    An appropriate non-proliferation treaty should not discriminate among the non-weapon states, but should seek a cooperative approach with all countries seeking nuclear power and willing to accept international safeguards. Near-term proliferation problems, represented by nations already on the threshold of weapon capability, should not be confused with the long-term problem of world-wide nuclear development. The first can be handled with incentives and disincentives imposed on specific countries, while the latter involves the distribution of plutonium on the basis of alternative fuel cycles. To retain world leadership, U.S. efforts along these lines should be to encourage a dialogue between suppliers and recipients and to coordinate the economic and security issues of its own non-proliferation and foreign policies. One option is a U.S. commitment to a multinational fuel storage and reprocessing facility. Technical evaluation and demonstration of alternative fuel cycles to reach an international consensus would be a parallel activity

  6. Status and prospect of non-proliferation activities of ISTC and STCU

    International Nuclear Information System (INIS)

    Richard, M.; Daoust Maleval, D.; Louvet, P.

    2009-01-01

    This article examines the role of the International Science and Technology Centre of Moscow (ISTC) and the Science and Technology Centre of Ukraine in Kiev (STCU) in preventing proliferation of the weapons of mass destruction (WMD) expertise and know-how of scientists and engineers from the Former Soviet Union countries. The Centres were created in the first half of the nineties, in the context of the collapse of the Soviet Union. This collapse raised very serious concerns: over the risk of former WMD scientists and engineers being recruited by States of concern or terrorist groups that wished to develop their own WMD capabilities and means of delivery; and the possibility that scientists and engineers would be driven to sell their knowledge, know-how or equipment in order to survive. Since the Centres' inception, the regional and international context has changed dramatically at both economic and strategic levels, in particular regarding non-proliferation and global security. Changes of a political and strategic nature in the former Soviet Union required the European Union to review its relationship with Russia, to reassess the importance of Central Asian Countries and the future of Ukraine as it is pulled between Russia and Europe. The Centres have had to adapt to these changes. The article draws from an evaluation of the Centres' non-proliferation activities, carried out by the authors between November 2006 and September 2007 at the request of the European Commission. Moreover, since completion of the mission, many events, important for the strategic relationships between E U, Russia and other Commonwealth of Independent States (CIS) countries occurred as the affirmation of Russia's regional leadership: its rearmament along with the stiffening of its relationships with western countries and some neighbours and closure to visitors; the Georgia-Russia conflict; and the Russia-Ukraine gas crisis. As CIS countries are more affected by the current economical crisis

  7. Environmental measurements and technology for non-proliferation objectives. Final report

    International Nuclear Information System (INIS)

    Broadway, J.A.

    1998-01-01

    The purpose of this study is to identify multi-disciplinary and single focus laboratories from the environmental and public health communities that can serve as technical center of opportunity for nuclear, inorganic and organic analyses. The objectives of the Office of Research and Development effort are twofold: (1) to identify the technology shortcomings and technologies gaps (thus requirements) within these communities that could benefit from state-of-the-art infield analysis technologies currently under development and (2) to promote scientist-to-scientist dialog and technical exchange under such existing US government internship programs (eg SABIT/USDOC) to improve skills and work relationships. Although the data analysis will focus on environmentally sensitive signatures and materials, the office of Research and Development wishes to further its nuclear non-proliferation objectives by assessing the current technical skill and ingenious analytical tools in less-developed countries so as to broaden the base of capability for multi-species measurement technology development

  8. The structure of German non-proliferation policy - past and future

    International Nuclear Information System (INIS)

    Mueller, H.

    1990-01-01

    West German nonproliferation policy has evolved through four phases: First German policy strived to regain the right to nuclear research and industrial development. Then West Germany struggled for participation in NATO nuclear decision-making. Following the conclusion of the NPT, the full development of a mature nuclear industry, including activities in the full fuel cycle, and the promotion of nuclear exports were the focus of national nuclear policy. Starting in the early eighties, political aspects became more important. International security, arms control and disarmament, and foreign reputation had a more prominent role than pure economic interests. In the future, the united Germany must take care not to repeat the sad scandals of the eighties. Its renunciation of nuclear weapons remains a pillar of European stability and a prerequisite for a European peace system. Together with its European partners, Germany can be expected to take a more active, supportive and effective role in international non-proliferation policy. (orig./HSCH) [de

  9. Nuclear proliferation

    International Nuclear Information System (INIS)

    Stencel, S.

    1978-01-01

    The terms and reactions to President Carter's nuclear policy, culminating in the 1978 Nuclear Non-Proliferation Act, are reviewed and analyzed. The new law increases restrictions on nuclear exports, encourages continued use of light water reactors in preference to plutonium-fueled reactors, and emphasizes technical solutions to proliferation problems. Critics of the law point out that it will hurt U.S. trade unfairly, that other countries do not have as many fuel options as the U.S. has, and that nuclear sales have as many political and economic as technical solutions. Compromise areas include new international safety guidelines, the possibility of an international nuclear fuel bank, and a willingness to consider each case on its merits. 21 references

  10. Director`s series on proliferation

    Energy Technology Data Exchange (ETDEWEB)

    Bailey, K.C. [ed.

    1993-09-07

    Two essays are included in this booklet. Their titles are ``The Dynamics of the NPT Extension Decision`` and ``North Korea`s Nuclear Gambit.`` The first paper discusses the conference to be held in 1995 to review the Nuclear Non-Proliferation Treaty (NPT) which will decide whether the treaty shall continue in force indefinitely, or shall be extended for an additional fixed period or periods. Topics relevant to this discussion are: Arms control issues, the nuclear test ban, the limited test ban treaty, the French nuclear testing moratorium, former Soviet nuclear weapons, Iraq, North Korea, nuclear-weapon-free zones, security, controls on nuclear weapon materials, peaceful uses of nuclear energy, safeguards, politics, and organizational and procedural issues. The second paper examines short, medium, and long term issues entailed in Korea`s nuclear proliferation. Topics considered include: Korean unification, North Korean politics, the nuclear issue as leverage, and the Nuclear Non- Proliferation Treaty.

  11. Abrupt climate-independent fire regime changes

    Science.gov (United States)

    Pausas, Juli G.; Keeley, Jon E.

    2014-01-01

    Wildfires have played a determining role in distribution, composition and structure of many ecosystems worldwide and climatic changes are widely considered to be a major driver of future fire regime changes. However, forecasting future climatic change induced impacts on fire regimes will require a clearer understanding of other drivers of abrupt fire regime changes. Here, we focus on evidence from different environmental and temporal settings of fire regimes changes that are not directly attributed to climatic changes. We review key cases of these abrupt fire regime changes at different spatial and temporal scales, including those directly driven (i) by fauna, (ii) by invasive plant species, and (iii) by socio-economic and policy changes. All these drivers might generate non-linear effects of landscape changes in fuel structure; that is, they generate fuel changes that can cross thresholds of landscape continuity, and thus drastically change fire activity. Although climatic changes might contribute to some of these changes, there are also many instances that are not primarily linked to climatic shifts. Understanding the mechanism driving fire regime changes should contribute to our ability to better assess future fire regimes.

  12. The history of Finnish nuclear non-proliferation policy during the cold war. What did the Finns know about nuclear weapons

    International Nuclear Information System (INIS)

    Ahosniemi, A.

    2004-03-01

    This article is a summary of the Finnish historical survey during the Cold War. In the article, I try to show how the Finnish Nuclear Non-Proliferation Policy during the Cold War is linked to the broader context of the Finnish foreign and security policy. In the research report I have focused on several questions. One of the most important is the following: What did the Finns know about nuclear weapons during the Cold War? And in this context scientific knowledge is meant by knowing something about nuclear weapons. Basically, the Finnish national based survey of nuclear non-proliferation policy attempted to investigate issues like the kind of research concerning Nuclear Technology in general, Nuclear weapons, and Nuclear weapon policies of super powers in Finland during the Cold War era. (author)

  13. miR-32 inhibits proliferation, epithelial–mesenchymal transition, and metastasis by targeting TWIST1 in non-small-cell lung cancer cells

    Directory of Open Access Journals (Sweden)

    Li L

    2016-03-01

    Full Text Available Lei Li,1,* Dapeng Wu2,* 1Department of Pneumology, 2Department of Radiotherapy, Huaihe Hospital of Henan University, Kaifeng, Henan, People’s Republic of China *These authors contributed equally to this work Background: By analyzing published microRNA microarray studies, miR-32 was found to be markedly reduced in non-small-cell lung cancer (NSCLC tissues compared with that in nontumor tissues. However, little is known about its role and molecular mechanism involved in NSCLC development and progression. Here, we report the effect of miR-32 on NSCLC cell proliferation, epithelial–mesenchymal transition (EMT, and metastasis. Methods: Quantitative real-time PCR was performed to detect the expression level of miR-32 in primary NSCLC cases and cell lines. miR-32-overexpressing H1299 and A549 cells were constructed by lipofection transfection. MTT, transwell chamber, and Western blot assays were used to assess the effect of miR-32 on proliferation, EMT, and metastasis of NSCLC cells, respectively. Target prediction and luciferase reporter assays were performed to investigate the targets of miR-32. Tumor formation assay in vivo was performed to investigate the antitumor effect of miR-32. Results: An inverse correlation existed between miR-32 expression level and NSCLC cell proliferation, EMT, and metastasis, and upregulation of miR-32 repressed NSCLC cell proliferation, EMT, and metastasis. Moreover, we identified and validated that TWIST1 was a direct target of miR-32, and miR-32 regulated NSCLC cell proliferation, EMT, and metastasis, at least in part via modulation of TWIST1. The animal experiments showed that overexpression of miR-32 inhibited the growth of NSCLC tumors in vivo. Keywords: non-small-cell lung cancer, miR-32, TWIST1, proliferation, EMT, nude mice

  14. Non-invasive classification of gas–liquid two-phase horizontal flow regimes using an ultrasonic Doppler sensor and a neural network

    International Nuclear Information System (INIS)

    Abbagoni, Baba Musa; Yeung, Hoi

    2016-01-01

    success of a clamp-on ultrasound sensor for flow regime classification that would be possible in industry practice. It is considerably more promising than other techniques as it uses a non-invasive and non-radioactive sensor. (paper)

  15. Non-invasive classification of gas-liquid two-phase horizontal flow regimes using an ultrasonic Doppler sensor and a neural network

    Science.gov (United States)

    Musa Abbagoni, Baba; Yeung, Hoi

    2016-08-01

    success of a clamp-on ultrasound sensor for flow regime classification that would be possible in industry practice. It is considerably more promising than other techniques as it uses a non-invasive and non-radioactive sensor.

  16. Accelerator-driven subcritical systems - An analysis with a focus on non-proliferation and export control

    International Nuclear Information System (INIS)

    Andersson, Per; Nielsen, Fredrik; Sunhede, Daniel

    2013-01-01

    The Department of Nuclear Weapons Related Issues at The Swedish Defence Research Agency, FOI, as commissioned by the Swedish Radiation Safety Authority, SSM, conducted a study concerning Accelerator Driven Subcritical Systems, ADS, with emphasis on non-proliferation and export control. An ADS looks at first glance like a traditional nuclear reactor, but the nuclear core is designed to always remain subcritical, both during normal and off-normal conditions. Neutrons are instead supplied by an external source in the form of an proton accelerator and a spallation target. This report gives a short walk-through to the physical processes that governs the neutron flux and reactivity in the core and how they are affected by the design of the core including the accelerator and spallation target. Furthermore is the results from reactor core simulations presented, where the isotopic nuclear fuel inventory has been studied as a function of burn up and initial configuration. Finally the report contains an analysis of the potential risks involved from the perspective of nuclear proliferation and exports. This study shows that ADS in the future could constitute a proliferation concern. The subsystems and components in question share design and materials with the equivalent components in traditional reactors with the exception of the proton accelerator and spallation target, which is unique for accelerator driven systems

  17. Non-proliferation policy of the Republic of Kazakhstan

    International Nuclear Information System (INIS)

    Shkol'nik, V.S.; Zhantikin, T.M.

    1997-01-01

    The present abstract reveals the aspects of Kazakstan's non-proliferation policy. After acquiring independence in Kazakstan there remained a huge nuclear inheritance of the USSR. Kazakstan had to determine its policy regarding nuclear stuff. One of the most important test sites of the former USSR - Semipalatinsk test site - was closed. The Republic signed the Lisbon Protocols to the Treaty between the USSR and USA on the reduction and limitation of strategic and offensive arms. On December 13, 1993, Kazakstan and the IAEA concluded the IAEA Safeguards Agreement. All nuclear weapons were removed from Kazakstan territory, work resulting in military nuclear power use was terminated. A wide program on conversion of the former military research infrastructure is being performed with the support of some foreign countries. For instance Kazakstan / USA jointly work on withdrawing highly enriched nuclear materials from Ulba Metallurgical Plant to the USA enterprises for processing ('Sapphere'). Another conversion activity is liquidation of the former testing holes at Semipalatinsk test site. In relation to this there appeared an agreement between U.S. Department of defence and Ministry of Sciences and New Technologies of the Republic of Kazakstan (October, 3, 1995). A sensitive information is present at the area of the former test site. The traditional IAEA safeguards are used to nuclear facilities and nuclear materials

  18. Non-canonical distribution and non-equilibrium transport beyond weak system-bath coupling regime: A polaron transformation approach

    Science.gov (United States)

    Xu, Dazhi; Cao, Jianshu

    2016-08-01

    The concept of polaron, emerged from condense matter physics, describes the dynamical interaction of moving particle with its surrounding bosonic modes. This concept has been developed into a useful method to treat open quantum systems with a complete range of system-bath coupling strength. Especially, the polaron transformation approach shows its validity in the intermediate coupling regime, in which the Redfield equation or Fermi's golden rule will fail. In the polaron frame, the equilibrium distribution carried out by perturbative expansion presents a deviation from the canonical distribution, which is beyond the usual weak coupling assumption in thermodynamics. A polaron transformed Redfield equation (PTRE) not only reproduces the dissipative quantum dynamics but also provides an accurate and efficient way to calculate the non-equilibrium steady states. Applications of the PTRE approach to problems such as exciton diffusion, heat transport and light-harvesting energy transfer are presented.

  19. Does nuclear proliferation in Asia threaten the future of the NPT?

    International Nuclear Information System (INIS)

    Vandier, Pierre

    2005-01-01

    Asia is a region which presents all kinds of situation with respect to nuclear proliferation: nuclear countries, proliferating countries, countries non members of the NPT, countries violating the NPT, pacifist countries, threshold countries, and so on. Through an assessment of nuclear proliferation in Asia, the author first outlines the weaknesses of the Non Proliferation Treaty (NPT), and then discusses origins of tensions which may re-launch a nuclear arms race. In a third part, the author assesses the future of the Treaty within the arrangement for the struggle against nuclear proliferation as its has been strengthened in 2005

  20. Autonomia e relevância dos regimes The autonomy and relevance of regimes

    Directory of Open Access Journals (Sweden)

    Gustavo Seignemartin de Carvalho

    2005-12-01

    of norms and rules that create patterns of behavior and allow the convergence of the expectations of their participants in specific issue areas, in order to solve coordination problems that could lead to non-pareto-efficient outcomes. Considering that such definitions based merely on the "efficiency" of regimes do not seem to be sufficient to explain their effectiveness, the present article proposes a different definition for regimes: political arrangements that allow a redistribution of the gains of cooperation among the participants in certain issue areas, within an interdependence context. Regimes would thus be effective due to their autonomy and relevance - that is, due to their objective existence autonomously from their participants and their influence on the participants' behavior and expectations in ways that cannot be reduced to the individual action of any of them. This article begins with a brief discussion about terminological problems related to regime studies and with a definition of the concepts of autonomy and relevance. Then it classifies the authors that take part in this debate according to two distinct perspectives, one that denies (non-autonomists and the other that attributes (autonomists autonomy and relevance to regimes, briefly analyzing the authors and traditions that are more significant for this debate, focusing on autonomist authors and on arguments that back the hypothesis here presented. Finally, the article proposes an analytic decomposition of regimes into four main elements that give them autonomy and relevance: normativity, actors, specificity of the issue area and complex interdependence as context.

  1. North-East Asia: a risk of nuclear proliferation; Un risque de proliferation nucleaire en Asie du Nord-Est?

    Energy Technology Data Exchange (ETDEWEB)

    Courmont, B. [Centre d' Etudes Transatlantiques, 75 - Paris (France)

    2009-04-15

    North-East Asia is distinguished by being potentially one of the world's most nuclearised regions. It includes two nuclear powers recognised by the Non-Proliferation Treaty (Russia and China), a proliferating state (North Korea) and three countries that could very quickly complete nuclear programmes (Japan, South Korea and Taiwan). Now that the question of nuclear proliferation has again surfaced on the international strategic scene, and that North Korea's test of October 2006 has introduced a new security paradigm into the region, how real is the risk of nuclear proliferation in North-East Asia? (author)

  2. Statements commemorating the twentieth anniversary of the Treaty on the Non-Proliferation of Nuclear Weapons

    International Nuclear Information System (INIS)

    1988-08-01

    The document reproduces the following statements commemorating the twentieth anniversary of the Treaty on the Non-proliferation of Nuclear Weapons: Statement by the Secretary-General of the United Nations, statements on behalf of the depository Governments and statements on behalf of other Governments (Australia, Bangladesh, Canada, Costa Rica, Cyprus, Czechoslovakia, Egypt, Federal Republic of Germany, Greece, Hungary, Ireland, Japan, Liechtenstein, Mexico, the Netherlands, New Zealand, Solomon Islands, Spain, Sri Lanka, Switzerland, Thailand, Trinidad and Tobago, Western Samoa and Nordic Countries - Denmark, Finland, Iceland, Norway and Sweden)

  3. International proliferation on nuclear weapons

    International Nuclear Information System (INIS)

    Hill, J.

    1977-01-01

    The subject is dealt with under the following headings: introduction; routes to proliferation (preparation of U 235 , Pu 239 , U 233 ); nuclear power fuel cycles and proliferation; the fast reactor fuel cycle; security aspects of the existing fuel cycle; the IAEA and the nuclear non-proliferation treaty. It is concluded that 'the basis for sound international control exists, and taken together with the further technical steps which will be taken to make the existing fuel cycles more robust against the diversion of materials by terrorists and the abuse of civil nuclear power programmes by governments, we have good reason to proceed now with the orderly exploitation of ...nuclear energy...'. (U.K.)

  4. Implementing nuclear non-proliferation in Finland. Regulatory control, international cooperation and the comprehensive nuclear-test-ban treaty. Annual report 2007

    International Nuclear Information System (INIS)

    Haemaelaeinen, M.; Karhu, P.

    2008-04-01

    Regulatory control of nuclear materials (nuclear safeguards) is a prerequisite for the peaceful use of nuclear energy in Finland. In order to uphold our part of the international agreements on nuclear non-proliferation - mainly the Non-Proliferation Treaty (NPT). This regulatory control is exercised by the Nuclear Materials Section of the Finnish Radiation and Nuclear Safety Authority (STUK). Nuclear safeguards are applied to all materials and activities that can lead to the proliferation of nuclear weapons or sensitive nuclear technology. These safeguards include nuclear materials accountancy, control, security and reporting. The results of STUK's nuclear safeguards inspection activities in 2007 continued to demonstrate that Finnish licence holders take good care of their nuclear materials. There were no indications of undeclared nuclear materials or activities and the inspected materials and activities were in accordance with the licence holders' declarations. STUK remarked on the nuclear safeguards systems of two licence holders in 2007, setting required actions for them to correct their reporting and to update the descriptions of their procedures. Neither the IAEA nor the European Commission made any remarks nor did they present any required actions based on their inspections. By their nuclear materials accountancy and control systems, all licence holders enabled STUK to fulfil its own obligations under the international agreements relevant to nuclear safeguards

  5. Beta Risk and Regime Shift in Market Volatility

    OpenAIRE

    Don U.A. Galagedera; Roland G. Shami

    2004-01-01

    In this paper, we relate security returns in the thirty securities in the Dow Jones index to regime shifts in the market portfolio (S&P500) volatility. We model market volatility as a multiple-state Markov switching process of order one and estimate non-diversifiable security risk (beta) in the different market volatility regimes. We test the significance of the premium of the beta risk associated with the different market regimes and find evidence of a relationship between security return an...

  6. Monitoring non-proliferation of weapons of mass destruction: Can regional CBMs play a role?

    International Nuclear Information System (INIS)

    Sood, R.

    1994-01-01

    The experience of regional Confidence Building Measures (CBM), has only limited applicability for tackling proliferation of weapons of mass destruction. Where the international norm has developed as in the case of biological and chemical weapons, through international disarmament treaties, regional initiatives can strengthen this norm. Where a norm is less well-founded, regional initiatives are not likely to succeed. Specifically, with regard to nuclear weapons, consensus on negotiations for a comprehensive test ban treaty and a convention for prohibition of production of fissile materials for nuclear weapons purposes and explosive devices is a positive development. Successful conclusion of these universal and verifiable treaties will go a long way to strengthening the international norm against proliferation. Two other measures are critical - a development of a non-use assurance and commencement of multilateral nuclear disarmament negotiations among all five nuclear weapon States. If the international community witnesses improvement in these areas, regional negotiations will be stimulated. Therefore, the primary focus should be on developing an international norm to eliminate weapons of mass destruction. Regional efforts will take their cue from these international norms and would result in CBMs that are consistent with the international norm

  7. Flow regime effects on non-cavitating injection nozzles over spray behavior

    Energy Technology Data Exchange (ETDEWEB)

    Payri, R., E-mail: rpayri@mot.upv.e [CMT-Motores Termicos, Universidad Politecnica de Valencia, Camino de Vera s/n, Valencia E-46022 (Spain); Salvador, F.J.; Gimeno, J.; Novella, R. [CMT-Motores Termicos, Universidad Politecnica de Valencia, Camino de Vera s/n, Valencia E-46022 (Spain)

    2011-02-15

    This paper deals with the influence of flow regime (laminar, transition or turbulent) on the internal flow behavior, and how it affects the spray development in diesel nozzles. In particular, the research described here aims at studying and quantifying the internal flow regime effects on the spray behavior. With this purpose, internal flow results, based on mass flow rate and momentum flux measurements performed on three different tapered nozzles and which helped to determine the flow regime, has been taken into account as a point of departure for the spray behavior analysis. Thus, in this work, spray macroscopic visualization tests have been performed and analyzed which clearly revealed a change in the behavior of the angle and penetration of the spray related to the change of the flow nature. Moreover, with all the experimental data available, it has been possible to relate macroscopic parameters of the spray with those describing the internal flow (momentum and effective velocity) or the geometry of the nozzle (length or diameter) through correlations.

  8. Non-Eosinophilic Nasal Polyps Shows Increased Epithelial Proliferation and Localized Disease Pattern in the Early Stage.

    Directory of Open Access Journals (Sweden)

    Dong-Kyu Kim

    Full Text Available Non-eosinophilic nasal polyps (NPs show less inflammatory changes and are less commonly associated with lower airway inflammatory disorders such as asthma, compared with eosinophilic NPs. However, the development of non-eosinophilic NPs which is a predominant subtype in Asian population still remains unclear.A total of 81 patients (45 with non-eosinophilic NPs and 36 with eosinophilic NPs were enrolled. Clinical information and computed tomography (CT, endoscopic, and histological findings were investigated. Tissue samples were analyzed for total IgE levels and for mRNA expression levels of interleukin (IL-4, IL-5, IL-13, interferon (IFN-γ, tumor necrosis factor (TNF-α, IL-17A, IL-22, IL-23p19, transforming growth factor (TGF-β1, TGF-β2, TGF-β3, and periostin. Immunostaining assessment of Ki-67 as a proliferation marker was performed.We found that epithelial in-growing patterns such as pseudocysts were more frequently observed in histological and endoscopic evaluations of non-eosinophilic NPs, which was linked to increase epithelial staining of Ki-67, a proliferating marker. Eosinophilic NPs were characterized by high infiltration of inflammatory cells, compared with non-eosinophilic NPs. To investigate the developmental course of each subtype, CT was analyzed according to CT scores and subtypes. Non-eosinophilic NPs showed more localized pattern and maxillary sinus involvement, but lesser olfactory involvement in early stage whereas eosinophilic NPs were characterized by diffuse ethmoidal and olfactory involvement. In addition, high ethmoidal/maxillary (E/M CT scores, indicating ethmoidal dominant involvement, were one of surrogate markers for eosinophilic NP. E/M CT scores was positively correlated with levels of TH2 inflammatory markers, including IL-4, IL-5, periostin mRNA expression and total IgE levels in NPs, whereas levels of the TH1 cytokine, IFN- γ were inversely correlated. Moreover, if the combinatorial algorithm meet the three

  9. Implications of the Ukraine Crisis for Security, Non-Proliferation and Deterrence in North East Asia

    International Nuclear Information System (INIS)

    Farghen, Morgane

    2014-01-01

    The Ukraine crisis has been a 'wake up' call for Europe but its implication in Asia should be also be considered. The Russian 'coup de force' in Ukraine has created a psychological trauma in Western countries not only amongst political and military leaders but also in the general population by its reminiscence of Cold war thinking and by pointing to the risk of a military conflict in Europe. Moreover the Russian attempt to change the borders by force could create a dangerous precedent and produce an undesirable 'butterfly effects' in the rest of the world. In North East Asia, the stability in a context of rising powers and proliferation risks, relies on a status quo based upon the partition of the Korean peninsula, a de facto autonomy of Taiwan and a Japanese administration over the Senkaku-Diaoyu islands. As the status quo is increasingly challenged by revisionist powers, the question is worth to be raised: what are the implications of the Ukraine crisis for security, non-proliferation, and deterrence in North East Asia?

  10. Scalloped a member of the Hippo tumor suppressor pathway controls mushroom body size in Drosophila brain by non-canonical regulation of neuroblast proliferation.

    Science.gov (United States)

    Rohith, Basavanahalli Nanjundaiah; Shyamala, Baragur Venkatanarayanasetty

    2017-12-15

    Cell proliferation, growth and survival are three different basic processes which converge at determining a fundamental property -the size of an organism. Scalloped (Sd) is the first characterised transcriptional partner to Yorkie (Yki), the downstream effector of the Hippo pathway which is a highly potential and evolutionarily conserved regulator of organ size. Here we have studied the hypomorphic effect of sd on the development of Mushroom Bodies (MBs) in Drosophila brain. We show that, sd non-function results in an increase in the size of MBs. We demonstrate that, sd regulation on MB size operates through multiple routes. Sd expressed in the differentiated MB neurons, imposes non-cell autonomous repression on the proliferation of MB precursor cells, and Sd expression in the MB neuroblasts (NB) cell autonomously represses mushroom body neuroblast (MBNB) proliferation. Further Sd in Kenyon cells (KCs) imparts a cell autonomous restriction on their growth. Our findings are distinctive because, while the classical sd loss of function phenotypes in eye, wing and lymph gland are reported as loss of tissue or reduced organ size, the present study shows that, Sd inactivation in the developing MB, promotes precursor cell proliferation and results in an increase in the organ size. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. The proliferation of massive destruction weapons and ballistic missiles

    International Nuclear Information System (INIS)

    Schmitt, M.

    1996-01-01

    The author studies the actual situation of nuclear deterrence policies, the possibilities of use chemical weapons as massive destructions weapons for non nuclear governments. The situation of non proliferation of nuclear weapons took a new interest with the disintegration of the communism block, but it seems that only few nuclear matter disappeared towards proliferating countries. The denuclearization of Bielorussia, Ukraine and Kazakhstan makes progress with the START I treaty; China has signed the Non proliferation treaty in 1992, it conducts an export policy in matter of equipment and know-how, towards Iran, Pakistan, North Korea, Saudi Arabia and Syria. In a future of ten years, countries such, Iran, North Korea could catch up with Israel, India and Pakistan among non declared nuclear countries. For chemical weapon, Libya, Iran and Syria could catch up with Iraq. (N.C.)

  12. Nuclear proliferation in South Asia; La proliferation nucleaire en Asie du Sud

    Energy Technology Data Exchange (ETDEWEB)

    Lamballe, A

    2007-07-15

    Neither India nor Pakistan has signed the Nuclear Non-Proliferation Treaty or the Comprehensive Test Ban Treaty.By carrying out tests in 1998, they therefore violated no international agreement but dealt a severe blow to non-proliferation by inciting other countries, including Iran, to develop nuclear weapons. The purpose of India strike force is to deter China; Pakistan hopes that with a credible strike force it will be able to deter any major attack by India. The nuclear phenomenon is now firmly entrenched in the minds of all those on the subcontinent, where the arms race continues without let-up on all fronts: witness the many launches of ballistic and cruise missiles by both countries. And now that radical Islamist movements are showing an interest in nuclear weapons systems there is a risk of tipping from the rational to the irrational world, with all its attendant dangers. (author)

  13. IPSN and the mastery of proliferation risks; L'IPSN et la maitrise des risques de proliferation

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-04-14

    Since 20 years, the French Institute of Nuclear Protection and Safety (IPSN) works for the reinforcement of the efficiency of the actions against nuclear proliferation. This dossier takes stock of the means and action developed by the IPSN in this domain: nuclear and chemical proliferation: towards a reinforced mastery of risks (status of proliferation during the last 10 years, the aim of the international and national controls, the role of IPSN); nuclear proliferation: the technical control means of the IPSN (inspection, containment/surveillance of nuclear materials (PLUM and FUNE apparatuses), the cooperation between the IPSN and the Kurchatov institute (Russia)); the action of the IPSN in the application of international controls: example of chemistry (conventions, negotiations and expertise, inspections); appendixes: nuclear materials (declaration and permission thresholds), the different steps of the nuclear weapons non-proliferation policy. (J.S.)

  14. Naval nuclear propulsion and the international nonproliferation regime

    International Nuclear Information System (INIS)

    Guimaraes, Leonam dos Santos

    2005-01-01

    Nuclear powered attack submarine (SSN) acquisition by Non-Proliferation Treaty No- Nuclear Weapon State (NPT-NNWS) Navies does not imply nuclear weapon proliferation risks higher than those related to stationary research and power reactors. It must then be recognized that stringent restraints on supplies and political pressures on governments, both exercised very effectively by No-Proliferation Treaty - Nuclear Weapon State (NPT-NWS) against NPT-NNWS indigenous development of SSN and associated fuel cycle facilities, are fundamentally based on geopolitical and military strategic objectives. This practice is far from being related exclusively to the NPT spirit: in fact, it is a matter of freedom at seas and not of nuclear proliferation. (author)

  15. The Structure and Content of Agreements between the Agency and States required in connection with the Treaty on the Non-Proliferation of Nuclear Weapons

    International Nuclear Information System (INIS)

    1972-06-01

    The Board of Governors has requested the Director General to use the material reproduced in this booklet as the basis for negotiating safeguards agreements between the Agency and non-nuclear-weapon States party to the Treaty on the Non-Proliferation of Nuclear Weapons

  16. The Structure and Content of Agreements between the Agency and States required in connection with the Treaty on the Non-Proliferation of Nuclear Weapons

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1972-06-15

    The Board of Governors has requested the Director General to use the material reproduced in this booklet as the basis for negotiating safeguards agreements between the Agency and non-nuclear-weapon States party to the Treaty on the Non-Proliferation of Nuclear Weapons.

  17. The Structure and Content of Agreements between the Agency and States required in connection with the Treaty on the Non-Proliferation of Nuclear Weapons

    International Nuclear Information System (INIS)

    2007-01-01

    The Board of Governors has requested the Director General to use the material reproduced in this booklet as the basis for negotiating safeguards agreements between the Agency and non-nuclear-weapon States party to the Treaty on the Non-Proliferation of Nuclear Weapons

  18. The Long Non-Coding RNA XIST Controls Non-Small Cell Lung Cancer Proliferation and Invasion by Modulating miR-186-5p

    Directory of Open Access Journals (Sweden)

    Haoyou Wang

    2017-04-01

    Full Text Available Background/Aims: Long non-coding RNAs (lncRNAs are key players in the development and progression of human cancers. The lncRNA XIST (X-inactive specific transcript has been shown to be upregulated in human non-small cell lung cancer (NSCLC; however, its role and molecular mechanisms in NSCLC cell progression remain unclear. Methods: qRT-PCR was conducted to assess the expression of XIST and miR-186. Cell proliferation was detected using MTT assay. Cell invasion and migration were evaluated using transwell assay. Cell cycle distribution and apoptosis rates were analyzed by flow cytometry. Luciferase reporter assay was used to identify the direct regulation of XIST and miR-186. A RNA immunoprecipitation was used to analyze whether XIST was associated with the RNA-induced silencing complex (RISC. Results: We confirmed that XIST was upregulated in NSCLC cell lines and tissues. Functionally, XIST knockdown inhibited cancer cell proliferation and invasion, and induced apoptosis in vitro, and suppressed subcutaneous tumor growth in vivo. Mechanistic investigations revealed a reciprocal repressive interaction between XIST and miR-186-5p. Furthermore, we showed that miR-186-5p has a binding site for XIST. Our data also indicated that XIST and miR-186-5p are likely in the same RNA induced silencing complex. Conclusion: Together, our data revealed that XIST knockdown confers suppressive function in NSCLC and XIST may be a novel therapeutic marker in this disease.

  19. Nuclear proliferation and safeguards. Summary

    International Nuclear Information System (INIS)

    1982-03-01

    This comprehensive analysis of the technological, economic, and political factors affecting the potential spread of nuclear weapons proved useful in the congressional debate which culminated in the Nuclear Non-Proliferation Act of 1978. The report was subsequently published commercially and has been a frequently cited reference in the literature on proliferation and nuclear power. Despite developments since 1977, the information in the OTA report is still useful to those wishing to obtain an indepth understanding of the issues. Included is an analysis of why a nation might want nuclear weapons development program and the various sources of nuclear material are discussed. The control of proliferation is considered as well as its relation to the nuclear industry

  20. The international legal regime governing the peaceful uses of nuclear energy

    International Nuclear Information System (INIS)

    Talaie, F.

    2004-01-01

    This paper studies the legal regime governing the peaceful uses of nuclear energy. It addresses the issue of the prevention of the use by states of the nuclear weapons (as the most destructive weapon of mass destruction) and their elimination as the main purpose for maintaining international peace and security.Then, the paper presents examples of peaceful applications of nuclear energy. It points out that the peaceful uses of nuclear materials and technology are not hampered by obligation of States not to divert these materials into nuclear weapons. In this context, the paper analyses the provisions of the main international and regional treaties related to the nuclear energy (especially the Treaty on Non-proliferation of Nuclear Weapons and the Regional Treaty of TLATELOLCO). It also examines the international mechanism for monitoring the peaceful uses of nuclear energy and in particular studies the role of the International Atomic Energy Agency in the prevention of the proliferation of nuclear weapons through the application of safeguards agreements and the additional protocol to these agreements. One special part of the paper is dedicated to Iran and the peaceful uses of nuclear energy. The paper concludes that the existing rules of international law do not prevent any State from using and applying nuclear energy and technology for peaceful uses. These rules only make such uses subject to a comprehensive verification mechanism through the International Atomic Energy Agency safeguards agreements and the additional protocol the these agreements

  1. GM-CSF produced by non-hematopoietic cells is required for early epithelial cell proliferation and repair of injured colonic mucosa1,2

    Science.gov (United States)

    Egea, Laia; McAllister, Christopher S.; Lakhdari, Omar; Minev, Ivelina; Shenouda, Steve; Kagnoff, Martin F.

    2012-01-01

    GM-CSF is a growth factor that promotes the survival and activation of macrophages and granulocytes, and dendritic cell (DC) differentiation and survival in vitro. The mechanism by which exogenous GM-CSF ameliorates the severity of Crohn’s disease in humans and colitis in murine models has been considered mainly to reflect its activity on myeloid cells. We used GM-CSF deficient (GM-CSF−/−) mice to probe the functional role of endogenous host-produced GM-CSF in a colitis model induced after injury to the colon epithelium. Dextran sodium sulfate (DSS) at doses that resulted in little epithelial damage and mucosal ulceration in wild type (WT) mice resulted in marked colon ulceration and delayed ulcer healing in GM-CSF−/− mice. Colon crypt epithelial cell proliferation in vivo was significantly decreased in GM-CSF−/− mice at early times after DSS injury. This was paralleled by decreased expression of crypt epithelial cell genes involved in cell cycle, proliferation, and wound healing. Decreased crypt cell proliferation and delayed ulcer healing in GM-CSF−/− mice were rescued by exogenous GM-CSF, indicating the lack of a developmental abnormality in the epithelial cell proliferative response in those mice. Non-hematopoietic cells and not myeloid cells produced the GM-CSF important for colon epithelial proliferation after DSS-induced injury as revealed by bone marrow chimera and DC depletion experiments, with colon epithelial cells being the cellular source of GM-CSF. Endogenous epithelial cell produced GM-CSF has a novel non-redundant role in facilitating epithelial cell proliferation and ulcer healing in response to injury of the colon crypt epithelium. PMID:23325885

  2. The Structure and Content of Agreements between the Agency and States required in connection with the Treaty on the Non-Proliferation of Nuclear Weapons

    International Nuclear Information System (INIS)

    1971-05-01

    The Board of Governors has requested the Director General to use the material reproduced in this booklet as the basis for negotiating safeguards agreements between the Agency and non-nuclear-weapon States party to the Treaty on the Non-Proliferation of Nuclear Weapons [es

  3. The Structure and Content of Agreements between the Agency and States required in connection with the Treaty on the Non-Proliferation of Nuclear Weapons

    International Nuclear Information System (INIS)

    1975-04-01

    The Board of Governors has requested the Director General to use the material reproduced in this booklet as the basis for negotiating safeguards agreements between the Agency and non-nuclear-weapon States party to the Treaty on the Non-Proliferation of Nuclear Weapons [ru

  4. Strengthening the nuclear nonproliferation regime: focus on the civilian nuclear fuel cycle

    International Nuclear Information System (INIS)

    Saltiel, David H.; Pregenzer, Arian Leigh

    2005-01-01

    Leaders around the world and across the ideological spectrum agree that the global nonproliferation regime is facing a serious test. The emergence of sophisticated terrorist networks, black markets in nuclear technology, and technological leaps associated with globalization have conspired to threaten one of the most successful examples of international cooperation in history. The rampant proliferation of nuclear weapons that was predicted at the start of the nuclear age has been largely held in check and the use of those weapons avoided. Nonetheless, with the thirty-fifth anniversary of the Treaty on the Nonproliferation of Nuclear Weapons (NPT), the threat of nuclear proliferation seems more serious than ever. Although experts readily concede that there exist many pathways to proliferation, the threat posed by the misuse of the civilian nuclear fuel cycle has received considerable recent attention. While the connection between nuclear energy and nonproliferation has been a topic of discussion since the dawn of the nuclear age, world events have brought the issue to the forefront once again. United States President George W. Bush and International Atomic Energy Agency (IAEA) Director General Mohammad ElBaradei are among those who have highlighted proliferation risks associated with civilian nuclear power programs and called for revitalizing the nuclear nonproliferation regime to address new threats. From the possibility of diversion or theft of nuclear material or technology, to the use of national civilian programs as a cover for weapons programs - what some have called latent proliferation - the fuel cycle appears to many to represent a glaring proliferation vulnerability. Just as recognition of these risks is not new, neither is recognition of the many positive benefits of nuclear energy. In fact, a renewed interest in exploiting these benefits has increased the urgency of addressing the risks. Global energy demand is expected to at least double by the middle of

  5. High glucose contributes to the proliferation and migration of non-small cell lung cancer cells via GAS5-TRIB3 axis.

    Science.gov (United States)

    Ding, Cheng-Zhi; Guo, Xu-Feng; Wang, Guo-Lei; Wang, Hong-Tao; Xu, Guang-Hui; Liu, Yuan-Yuan; Wu, Zhen-Jiang; Chen, Yu-Hang; Wang, Jiao; Wang, Wen-Guang

    2018-01-24

    Despite the growing number of studies exhibited an association of diabetes mellitus (DM) and lung cancer progression, the concrete mechanism of DM aggravating lung cancer has not been elucidated. This study was to investigate whether and how high glucose (HG) contribute to the proliferation and migration of non-small cell lung cancer (NSCLC) cells in vitro. In the present study, we confirmed that HG promoted the proliferation and migration of NSCLC cells, and also induced an anti-apoptosis effect on NSCLC cells. Moreover, HG inhibited the expression of GAS5 in NSCLC cells but elevated the protein level of TRIB3. GAS5 overexpression promoted the degradation of TRIB3 protein by ubiquitination and inhibited the HG induced-proliferation, anti-apoptosis and migration of NSCLC cells. Importantly, TRIB3 overexpression reversed the effects of GAS5 on the HG-treated NSCLC cells. Taken together, down-regulated GAS5 by HG significantly enhanced the proliferation, anti-apoptosis and migration in NSCLC cells through TRIB3, thus promoting the carcinogenesis of NSCLC. ©2018 The Author(s).

  6. Non-intrusive long-term monitoring approaches

    International Nuclear Information System (INIS)

    Smathers, D.; Mangan, D.

    1998-01-01

    In order to promote internatinal confidence that the US and Russia are disarming per their commitments under Article 6 of the Non-Proliferation Treaty, an international verification regime may be applied to US and Russian excess fissile materials. Initially, it is envisioned that this verification regime would be applied at storage facilities; however, it should be anticipated that the verification regime would continue throughout any material disposition activities, should such activities be pursued. once the materials are accepted into the verification regime, it is assumed that long term monitoring will be used to maintain continuity of knowledge. The requirements for long term storage monitoring include unattended operation for extended periods of time, minimal intrusiveness on the host nation's safety and security activities, data collection incorporating data authentication, and monitoring redundancy to allow resolution of anomalies and to continue coverage in the event of equipment failures. Additional requirements include effective data review and analysis processes, operation during storage facility loading, procedure for removal of inventory items for safety-related surveillance, and low cost, reliable equipment. A monitoring system might include both continuous monitoring of storagecontainers and continuous area monitoring. These would be complemented with periodic on-site inspections. A fissile material storage facility is not a static operation. The initial studies have shown there are a number of valid reasons why a host nation may need them to remove material from the storage facility. A practical monitoring system must be able to accommodate necessary material movements

  7. The motivations of proliferating countries. Final report

    International Nuclear Information System (INIS)

    Archambault, Jean-Claude; Daguzan, Jean-Francois; Pasco, Xavier; Sitt, Bernard

    2006-01-01

    This report is based on previous works made by the GSPP group (GSPP stands for geographic-social-psychological-political) which defined conceptual backgrounds for a new approach to nuclear proliferation, notably by introducing an associated method, the GSPP method, which is used in this study. Thus, this report first presents the GSPP method through its application to the analysis of the decision dynamics in the case of a proliferating State, a discussion of the seven determining factors (national resources, history and strategic context, type of political regime, leader's history and personal typology, international dependencies and alliances, elites and mediators, public opinions), a discussion of the interactions between these factors, an application of the first determining factor, and an application of the GSPP method to the case of biological and chemical proliferation. In the next part, the authors propose sheets which report the application of the method to different countries (Iran, Israel, Iraq, Algeria, Libya, China, India, Pakistan, North and South Korea, Taiwan, Japan, Australia, Indonesia, South Africa). The content and the exploitation of these sheets is then discussed, and the authors address the perspective of development of a GSPP model, notably by using the Maslowe pyramid. They propose an application of this model to the case of Iran

  8. Cell cycles and proliferation patterns in Haematococcus pluvialis

    Science.gov (United States)

    Zhang, Chunhui; Liu, Jianguo; Zhang, Litao

    2017-09-01

    Most studies on Haematococcus pluvialis have been focused on cell growth and astaxanthin accumulation; far less attention has been paid to cell cycles and proliferation patterns. The purpose of this study was to clarify cell cycles and proliferation patterns in H. pluvialis microscopically using a camera and video recorder system. The complicated life history of H. pluvialis can be divided into two stages: the motile stage and the non-motile stage. All the cells can be classified into forms as follows: motile cell, nonmotile cell, zoospore and aplanospore. The main cell proliferation, both in the motile phase and non-motile phase in H. pluvialis, is by asexual reproduction. Under normal growth conditions, a motile cell usually produces two, sometimes four, and exceptionally eight zoospores. Under unfavorable conditions, the motile cell loses its flagella and transforms into a non-motile cell, and the non-motile cell usually produces 2, 4 or 8 aplanospores, and occasionally 20-32 aplanospores, which further develop into non-motile cells. Under suitable conditions, the non-motile cell is also able to release zoospores. The larger non-motile cells produce more than 16 zoospores, and the smaller ones produce 4 or 8 zoospores. Vegetative reproduction is by direct cell division in the motile phase and by occasional cell budding in the non-motile phase. There is, as yet, no convincing direct evidence for sexual reproduction.

  9. Nuclear Fuel Leasing, Recycling and proliferation: Modeling a Global View

    International Nuclear Information System (INIS)

    Crozat, M P; Choi, J; Reis, V H; Hill, R

    2004-01-01

    On February 11, 2004, U.S. President George W. Bush, in a speech to the National Defense University stated: ''The world must create a safe, orderly system to field civilian nuclear plants without adding to the danger of weapons proliferation. The world's leading nuclear exporters should ensure that states have reliable access at reasonable cost to fuel for civilian reactors, so long as those states renounce enrichment and reprocessing. Enrichment and reprocessing are not necessary for nations seeking to harness nuclear energy for peaceful purposes.'' This concept would require nations to choose one of two paths for civilian nuclear development: those that only have reactors and those that contain one or more elements of the nuclear fuel cycle, including recycling. ''Fuel cycle'' states would enrich uranium, manufacture and lease fuel to ''reactor'' states and receive the reactor states' spent fuel. All parties would accede to stringent security and safeguard standards, embedded within a newly invigorated international regime. Reactor states would be relieved of the financial, environmental (and political) burden of enriching and manufacturing fuel and dealing with spent fuel. Fuel cycle states would potentially earn money on leasing the fuel and perhaps on sales of reactors to the reactor states. Such a leasing concept is especially interesting in scenarios which envision growth in nuclear power, and an important consideration for such a nuclear growth regime is the role of recycling of civilian spent fuel. Recycling holds promise for improved management of spent fuel and efficient utilization of resources, but continues to raise the specter of a world with uncontrolled nuclear weapons proliferation. If done effectively, a fuel-leasing concept could help create a political and economic foundation for significant growth of clean, carbon-free nuclear power while providing a mechanism for significant international cooperation to reduce proliferation concern. This

  10. Proliferation resistance design of a plutonium cycle (Proliferation Resistance Engineering Program: PREP)

    Energy Technology Data Exchange (ETDEWEB)

    Sorenson, R.J.; Roberts, F.P.; Clark, R.G.

    1979-01-19

    This document describes the proliferation resistance engineering concepts developed to counter the threat of proliferation of nuclear weapons in an International Fuel Service Center (IFSC). The basic elements of an International Fuel Service Center are described. Possible methods for resisting proliferation such as processing alternatives, close-coupling of facilities, process equipment layout, maintenance philosophy, process control, and process monitoring are discussed. Political and institutional issues in providing proliferation resistance for an International Fuel Service Center are analyzed. The conclusions drawn are (1) use-denial can provide time for international response in the event of a host nation takeover. Passive use-denial is more acceptable than active use-denial, and acceptability of active-denial concepts is highly dependent on sovereignty, energy dependence and economic considerations; (2) multinational presence can enhance proliferation resistance; and (3) use-denial must be nonprejudicial with balanced interests for governments and/or private corporations being served. Comparisons between an IFSC as a national facility, an IFSC with minimum multinational effect, and an IFSC with maximum multinational effect show incremental design costs to be less than 2% of total cost of the baseline non-PRE concept facility. The total equipment acquisition cost increment is estimated to be less than 2% of total baseline facility costs. Personnel costs are estimated to increase by less than 10% due to maximum international presence. 46 figures, 9 tables.

  11. Proliferation resistance design of a plutonium cycle (Proliferation Resistance Engineering Program: PREP)

    International Nuclear Information System (INIS)

    Sorenson, R.J.; Roberts, F.P.; Clark, R.G.

    1979-01-01

    This document describes the proliferation resistance engineering concepts developed to counter the threat of proliferation of nuclear weapons in an International Fuel Service Center (IFSC). The basic elements of an International Fuel Service Center are described. Possible methods for resisting proliferation such as processing alternatives, close-coupling of facilities, process equipment layout, maintenance philosophy, process control, and process monitoring are discussed. Political and institutional issues in providing proliferation resistance for an International Fuel Service Center are analyzed. The conclusions drawn are (1) use-denial can provide time for international response in the event of a host nation takeover. Passive use-denial is more acceptable than active use-denial, and acceptability of active-denial concepts is highly dependent on sovereignty, energy dependence and economic considerations; (2) multinational presence can enhance proliferation resistance; and (3) use-denial must be nonprejudicial with balanced interests for governments and/or private corporations being served. Comparisons between an IFSC as a national facility, an IFSC with minimum multinational effect, and an IFSC with maximum multinational effect show incremental design costs to be less than 2% of total cost of the baseline non-PRE concept facility. The total equipment acquisition cost increment is estimated to be less than 2% of total baseline facility costs. Personnel costs are estimated to increase by less than 10% due to maximum international presence. 46 figures, 9 tables

  12. Aperiodic pressure pulsation under non optimal hydraulic turbine regimes at low swirl number

    Science.gov (United States)

    Skripkin, S. G.; Tsoy, M. A.; Kuibin, P. A.; Shtork, S. I.

    2017-09-01

    Off-design operating conditions of hydraulic turbines is hindered by pressure fluctuations in the draft tube of the turbine. A precessing helical vortex rope develops, which imperils the mechanical structure and limits the operation flexibility of hydropower station. Understanding of the underlying instabilities of precessing vortex rope at low swirl number is incomplete. In this paper flow regimes with different residual swirl is analysed, particular attention is paid to the regime with a small swirl parameter. Study defines upper and low boundaries of regime where aperiodic pressure surge is observed. Flow field at the runner exit is investigated by Laser Doppler Velocimetry and high-speed visualizations, which are complemented draft tube wall pressure measurements.

  13. Evidence for a role of Collapsin response mediator protein-2 in signaling pathways that regulate the proliferation of non-neuronal cells

    International Nuclear Information System (INIS)

    Tahimic, Candice Ginn T.; Tomimatsu, Nozomi; Nishigaki, Ryuichi; Fukuhara, Akiko; Toda, Tosifusa; Kaibuchi, Kozo; Shiota, Goshi; Oshimura, Mitsuo; Kurimasa, Akihiro

    2006-01-01

    Collapsin response mediator protein-2 or Crmp-2 plays a critical role in the establishment of neuronal polarity. In this study, we present evidence that apart from its functions in neurodevelopment, Crmp-2 is also involved in pathways that regulate the proliferation of non-neuronal cells through its phosphorylation by regulatory proteins. We show that Crmp-2 undergoes dynamic phosphorylation changes in response to contact inhibition-induced quiescence and that hyperphosphorylation of Crmp-2 occurs in a tumor. We further suggest that de-regulation of Crmp-2 phosphorylation levels at certain amino acid residues may lead to aberrant cell proliferation and consequently, tumorigenesis

  14. Analysis of nuclear export control system and implementing international nonproliferation regime in China

    International Nuclear Information System (INIS)

    Kim, J. S.; Lee, J. S.; Ahn, J. S.; Kim, B. G.; Min, K. S.

    2000-01-01

    China's exporting behaviour of nuclear items had been disconnected from the international non-proliferation regime such as IAEA safeguards and export control related with peaceful use of nuclear energy since 1970s. Especially, China had been one of principle suppliers of nuclear facility and technologies to Pakistan and Iran which had developed nuclear weapon programs. On the other hand, according to the rapid growth of economic scale after China began to open to the world, an active program for nuclear power plant as an electricity source had established. This means that China have surfaced as a big market to Korean nuclear industries. Regarding this, the paper dealt with the nuclear export control matters, i.e. the history of nuclear export control system and analyzed on background of enforcement of U.S.-China Nuclear Cooperation Agreement that had been apolitical issue between U.S. and China. Prospects toward conforming its nuclear export policies, laws and regulations to international standards also analyzed in results

  15. The strengthening of international regime of protection of the nuclear materials and other radioactive sources

    International Nuclear Information System (INIS)

    Shiganbayev, E.

    2001-01-01

    Full text: The widening of export streams satisfies the interest of any state, but at the same time the interests of individual countries and the whole international community requires the limitation of export of goods and technologies which are potentially dangerous. The decision of this problem, finding of the optimal balance between the devotion of the principles of free trade and the necessity of limiting the danger export is one of the main tasks of the national system of security of the Republic of Kazakhstan. Kazakhstan is a country with a policy of nonproliferation. This important element of the policy of the country, directed to maintenance and strengthening of the international security, becomes the priority trend in the foreign policy of Kazakhstan. The international community decides this problem under the Comprehensive Nuclear Test Ban Treaty (CTBT), Treaty on the Non-Proliferation of Nuclear Weapons (NPT), and the Convention on the Prohibition of the Development Production and Stockpiling of Bacteriological (Biological) and Toxin Weapons and on the Destruction, Convention on the Prohibition of the Development, Production, Stockpiling and Use of Chemical Weapons and Their Destruction. At present there are four international regimes in control with the aim of nonproliferation of the weapons of mass destruction (WMD): The group of the nuclear supplies which deals with the questions of delivery of special nuclear materials and technologies, and also nuclear materials and double function technologies; Australian group works in the sphere of control for materials and technologies of chemical and biological weapons; The regime of the control of rocket technologies functioning with the aim to prevent the proliferation of rockets as means of delivery of weapon of mass destruction; Wassenaar agreement, regime of export control for usual armament, goods and double function technologies. Kazakhstan does not have nuclear weapons and participants in the Agreement

  16. Proliferation risks; Proliferatierisico's

    Energy Technology Data Exchange (ETDEWEB)

    Carchon, R

    1998-09-01

    The report gives an overview of different aspects related to safeguards of fissile materials. Existing treaties including the Non-Proliferation Treaty, and the Tlatelolco and the Rarotonga Treaties are discussed. An overview of safeguards systems for the control of fissile materials as well as the role of various authorities is given. An overall overview of proliferation risks, the physical protection of fissile materials and the trade in fissile materials is given. Finally, the status in problem countries and de facto nuclear weapon states is discussed.

  17. Report on the behalf of the Commission for Foreign Affairs on the bill project adopted by the Senate, bearing application of the additional protocol to the agreement between France, the European Atomic Energy Community, and the International Atomic Energy Agency related to the application of guarantees in France, signed in Vienna on the 22 September 1998. Nr 3428

    International Nuclear Information System (INIS)

    Destot, Michel

    2016-01-01

    This report first discusses an international context which requires a strengthened regime of nuclear non proliferation. It outlines that the struggle against nuclear proliferation is more than ever a matter of concern (a severe threat for peace, security and stability, a contrasted situation with noticeable advances in some countries and regions on the one hand, and severe proliferation crisis on the other hand). It analyses the contribution of the additional protocol to the strengthening of the non proliferation regime: a necessary strengthening of the IAEA guarantee system, the NPT as a keystone of the non proliferation regime, and a perfectible regime on other issues. The second part outlines that the bill project consolidates the French participation to the IAEA guarantee system. The Commission works are then reported, notably the detailed examination of the different bill project articles which deal with declaration obligations, international verification, penal arrangements, and arrangements related to overseas territories and other arrangements. Appendices propose an impact study, a comparative table between the text transmitted by the Senate and the provisions of the additional protocol, a comparison between the French additional protocol and the model adopter in 1997, a comparative table of additional protocols adopted by other countries, and a list of additional protocols

  18. Institutional design and regime effectiveness in transboundary river management – the Elbe water quality regime

    Directory of Open Access Journals (Sweden)

    I. Dombrowsky

    2008-02-01

    Full Text Available The literature on transboundary river management suggests that institutions play an important role in bringing about cooperation. However, knowledge about how such institutions should be designed in order to do so remains limited. One way to learn more about adequate institutional design is to assess the effectiveness of existing regimes, and to trace the causal relationships that lead to the respective outcomes. In order to gain further insights into the relationship between institutional design and regime effectiveness, this paper presents a study on the water quality regime of the International Commission for the Protection of the Elbe (ICPE. The analysis is based on a review of pertinent documents and ten qualitative interviews with Czech and German Commission members and NGO representatives. Particular emphasis has been put on determining the ICPE's specific contribution and the no-regime counterfactual as well as on the perceived expediency of the institutional arrangements. The study shows overall that the countries were relatively successful in improving water quality in the Elbe basin. However, this outcome can only partly be attributed to the ICPE itself. Furthermore, the ICPE's contribution towards achieving the various goals varied significantly between the different areas of activity: it was relatively significant where the main responsibility for action lay with the public authorities, such as in the area of wastewater treatment and the establishment of an international alarm plan and model, but was practically non-existent in the reduction of non-point pollution from agriculture, where success depended on the behavior of individual private actors (farmers. The commission contributed towards problem solving by serving as a forum for the joint identification of priorities for action from a basin-wide perspective. The resulting international obligations increased the power of national water administrations and their access to funds

  19. Simulating Non-Fickian Transport across Péclet Regimes by doing Lévy Flights in the Rank Space of Velocity

    Science.gov (United States)

    Most, S.; Dentz, M.; Bolster, D.; Bijeljic, B.; Nowak, W.

    2017-12-01

    Transport in real porous media shows non-Fickian characteristics. In the Lagrangian perspective this leads to skewed distributions of particle arrival times. The skewness is triggered by particles' memory of velocity that persists over a characteristic length. Capturing process memory is essential to represent non-Fickianity thoroughly. Classical non-Fickian models (e.g., CTRW models) simulate the effects of memory but not the mechanisms leading to process memory. CTRWs have been applied successfully in many studies but nonetheless they have drawbacks. In classical CTRWs each particle makes a spatial transition for which each particle adapts a random transit time. Consecutive transit times are drawn independently from each other, and this is only valid for sufficiently large spatial transitions. If we want to apply a finer numerical resolution than that, we have to implement memory into the simulation. Recent CTRW methods use transitions matrices to simulate correlated transit times. However, deriving such transition matrices require transport data of a fine-scale transport simulation, and the obtained transition matrix is solely valid for this single Péclet regime. The CTRW method we propose overcomes all three drawbacks: 1) We simulate transport without restrictions in transition length. 2) We parameterize our CTRW without requiring a transport simulation. 3) Our parameterization scales across Péclet regimes. We do so by sampling the pore-scale velocity distribution to generate correlated transit times as a Lévy flight on the CDF-axis of velocities with reflection at 0 and 1. The Lévy flight is parametrized only by the correlation length. We explicitly model memory including the evolution and decay of non-Fickianity, so it extends from local via pre-asymptotic to asymptotic scales.

  20. Time-lapse nanoscopy of friction in the non-Amontons and non-Coulomb regime.

    Science.gov (United States)

    Ishida, Tadashi; Sato, Takaaki; Ishikawa, Takahiro; Oguma, Masatsugu; Itamura, Noriaki; Goda, Keisuke; Sasaki, Naruo; Fujita, Hiroyuki

    2015-03-11

    Originally discovered by Leonard da Vinci in the 15th century, the force of friction is directly proportional to the applied load (known as Amontons' first law of friction). Furthermore, kinetic friction is independent of the sliding speed (known as Coulomb's law of friction). These empirical laws break down at high normal pressure (due to plastic deformation) and low sliding speed (in the transition regime between static friction and kinetic friction). An important example of this phenomenon is friction between the asperities of tectonic plates on the Earth. Despite its significance, little is known about the detailed mechanism of friction in this regime due to the lack of experimental methods. Here we demonstrate in situ time-lapse nanoscopy of friction between asperities sliding at ultralow speed (∼0.01 nm/s) under high normal pressure (∼GPa). This is made possible by compressing and rubbing a pair of nanometer-scale crystalline silicon anvils with electrostatic microactuators and monitoring its dynamical evolution with a transmission electron microscope. Our analysis of the time-lapse movie indicates that superplastic behavior is induced by decrystallization, plastic deformation, and atomic diffusion at the asperity-asperity interface. The results hold great promise for a better understanding of quasi-static friction under high pressure for geoscience, materials science, and nanotechnology.

  1. Laboratory Investigation of Rheology and Infiltration Process of Non-Newtonian Fluids through Porous Media in a Non-Isothermal Flow Regime for Effective Remediation of Contaminants

    Science.gov (United States)

    Naseer, F.

    2017-12-01

    Contamination of soil and groundwater by adsorbent (persistent) contaminants have been a major concern. Mine tailings, Acid mine drainage, waste disposal areas, active or abandoned surface and underground mines are some major causes of soil and water contamination. It is need of the hour to develop cost effective and efficient remediation techniques for clean-up of soil and aquifers. The objective of this research is to study a methodology of using non-Newtonian fluids for effective remediation of adsorbent contaminants in porous media under non-isothermal flow regimes. The research comprises of three components. Since, non-Newtonian fluid rheology has not been well studied in cold temperatures, the first component of the objective is to expose a non-Newtonian fluid (Guar gum solution) to different temperatures ranging from 30 °C through -5 °C to understand the change in viscosity, shear strength and contact angle of the fluid. Study of the flow characteristic of non-Newtonian fluids in complex porous media has been limited. Hence, the second component of this study will focus on a comparison of flow characteristics of a Newtonian fluid, non-Newtonian fluid and a combination of both fluids in a glass-tube-bundle setup that will act as a synthetic porous media. The study of flow characteristics will also be done for different thermal regimes ranging from -5 °C to 30 °C. The third component of the research will be to compare the effectiveness Guar gum to remediate a surrogate adsorbed contaminant at a certain temperature from the synthetic porous media. Guar gum is biodegradable and hence it is benign to the environment. Through these experiments, the mobility and behavior of Guar gum under varying temperature ranges will be characterized and its effectiveness in removing contaminants from soils will be understood. The impact of temperature change on the fluid and flow stability in the porous medium will be examined in this research. Guar gum is good suspension

  2. Experiment of ablative Rayleigh-Taylor instability in a strongly non linear regime on the National Ignition Facility

    International Nuclear Information System (INIS)

    Casner, A.; Masse, L.; Liberatore, S.; Delorme, B.; Jacquet, L.; Loiseau, P.; Smalyuk, V. A.; Martinez, D.; Remington, B. A.

    2012-01-01

    As the control of the development of Rayleigh-Taylor-type hydrodynamic instabilities is crucial to achieve efficient implosions on the Laser Megajoule, and as the complexity of these instabilities requires an experimental validation of theoretical models and of the associated numerical simulations, the authors briefly present a proposition of experiments aimed at studying the strongly non linear Rayleigh-Taylor instability on the National Ignition Facility (NIF). This should allow a regime of competition between bubbles to be achieved for the first time in direct attack. They evoke the first experiment performed in March 2013

  3. Towards the fourth review conference of the Non-Proliferation Treaty in 1990

    International Nuclear Information System (INIS)

    1989-01-01

    This publication focuses on the background of the Treaty on the Non-Proliferation of Nuclear Weapons (NPT), its main provisions and some of the major issues discussed at the three conferences that have thus far been held to review the operation of the Treaty. A fourth conference to review the operation of the Treaty will be held at Geneva from 20 August to 14 September 1990. It will be the last regular review conference before the convening, in 1995, of a conference which will ''decide whether the Treaty shall continue in force indefinitely or shall be extended for an additional fixed period or periods'' (article X, para.2). A Preparatory Committee (open to all parties) for the Fourth Review Conference has been established by the parties to the NPT, and 95 parties attended the first session, held in New York from 1 to 5 May 1989

  4. India and the NPT: separating substantive facts from normative fiction

    International Nuclear Information System (INIS)

    Srivastava, Anupam; Gahlaut, Seema

    2010-01-01

    This article examines the feasibility and advisability of India joining the Non-Proliferation Treaty (NPT). It demonstrates that (a) the non-proliferation regime, which is larger and more varied than the NPT, has received significant cooperation from India in the past; (b) that in order to effectively deal with further challenges from nuclear renaissance, nuclear deterrence, and terrorism, the regime will need to craft creative, non-NPT centric solutions like the US-India nuclear agreement, to co-opt India; and (c) that India's interest will be better served by trying to shape the regime from within rather than remaining a reasoned voice from without. (author)

  5. Proliferation resistance of small modular reactors fuels

    Energy Technology Data Exchange (ETDEWEB)

    Polidoro, F.; Parozzi, F. [RSE - Ricerca sul Sistema Energetico,Via Rubattino 54, 20134, Milano (Italy); Fassnacht, F.; Kuett, M.; Englert, M. [IANUS, Darmstadt University of Technology, Alexanderstr. 35, D-64283 Darmstadt (Germany)

    2013-07-01

    In this paper the proliferation resistance of different types of Small Modular Reactors (SMRs) has been examined and classified with criteria available in the literature. In the first part of the study, the level of proliferation attractiveness of traditional low-enriched UO{sub 2} and MOX fuels to be used in SMRs based on pressurized water technology has been analyzed. On the basis of numerical simulations both cores show significant proliferation risks. Although the MOX core is less proliferation prone in comparison to the UO{sub 2} core, it still can be highly attractive for diversion or undeclared production of nuclear material. In the second part of the paper, calculations to assess the proliferation attractiveness of fuel in typical small sodium cooled fast reactor show that proliferation risks from spent fuel cannot be neglected. The core contains a highly attractive plutonium composition during the whole life cycle. Despite some aspects of the design like the sealed core that enables easy detection of unauthorized withdrawal of fissile material and enhances proliferation resistance, in case of open Non-Proliferation Treaty break-out, weapon-grade plutonium in sufficient quantities could be extracted from the reactor core.

  6. Assessment of nuclear fuel cycles with respect to assurance of energy supply; economic aspects; environmental aspects; non-proliferation

    International Nuclear Information System (INIS)

    1979-01-01

    This paper, which was presented to all INFCE Working Groups gives a broad qualitative assessment in tabular form of the following five fuel cycles: LWR once-through, LWR with thermal recycle, HWR once-through, HTR with uranium recycle, fast breeder reactor. The assessment is given of the assurance of supply aspects, the macro- and micro-economic aspects, the environmental aspects, and the non-proliferation, including safeguards, aspects of each fuel cycle

  7. Third Non-Proliferation Treaty review conference and 29th regular session of the general conference of the International Atomic Energy Agency. Hearing before the Subcommittee on Energy, Nuclear Proliferation, and Government Processes of the Committee on Governmental Affairs, United States Senate, Ninety-Ninth Congress, First Session, November 20, 1985

    International Nuclear Information System (INIS)

    Anon.

    1985-01-01

    Ambassador Lewis A. Dunn of the US Arms Control and Disarmament Agency and Danny J. Boggs of DOE reported on two recent international conferences relating to non-proliferation of nuclear weapons and arms control. Dunn summarized the Non-Proliferation Treaty Review conference and its final declaration in which participants reaffirmed treaty principles and made recommendations for strengthening its efforts and enhancing its implementation. Boggs summarized the International Atomic Energy Agency (IAEA) conference, and noted the significance of China's recent entry into IAEA. They stressed that energy security is a key factor in the success of IAEA safeguards because it affects trade and international cooperation. US contributions to the success of non-proliferation policies depend upon our ability to share technological information with less advanced nations. Questions and responses and an appendix with the final declaration of the Review Conference follow the testimony

  8. The NPT regime: Progress and promises

    International Nuclear Information System (INIS)

    Dhanapala, Jayantha

    2001-01-01

    Full text: Thesis. The 'NPT regime' has arrived at a fateful crossroads. Though extended indefinitely in 1995, its future is my no means secure. The future 'progress' of this treaty will depend upon whether the 'promises' of its States parties are fully implemented and, eventually, upon the treaty's success in achieving fully universal membership. Challenges The treaty faces many short-term and longer-term challenges: Short term - The first Preparatory Committee meeting for the 2005 Review Conference will meet next year. NNWS will want to see some evidence of progress on nuclear disarmament (Art. VI), along the lines prescribed in the 13 'practical steps' agreed at the last Review Conference. Yet progress has been set back by: uncertainties over the future of the ABM Treaty; the failure of START II and the CTBT to enter into force; the lack of a FISMAT treaty and a treaty establishing a NWFZ in Central Asia; continued qualitative improvements in nuclear weapons; hints that nuclear testing may one day resume; the persistence of doctrines of first-use, pre-emptive use, and use against states that use CBW. Other compliance-related questions will arise over safeguards (e.g. the inability of the IAEA to conduct inspections in the DPRK; signs of a breakdown of the norm of full-scope IAEA safeguards, e.g. in South Asia). There are also concerns over the implementation of non-proliferation commitments (e.g. persisting allegations about nuclear weapon programmes in existing NNWS). The terrorist attacks in New York and Washington, D.C. on 11 September should also serve as a reminder of the new terrorist dangers relating to the possible use of weapons of mass destruction and unorthodox delivery systems. Longer term - Selectivity in the enforcement of NPT norms; unilateralism; IAEA funding uncertainties and shortfalls; difficulties in reaching universal membership (India, Pakistan, and Israel); continuing compliance problems with respect to both non-proliferation and

  9. Proliferation of massive destruction weapons: fantasy or reality?

    International Nuclear Information System (INIS)

    Duval, M.

    2001-01-01

    This article evaluates the threat of massive destruction weapons (nuclear, chemical, biological) for Europe and recalls the existing safeguards against the different forms of nuclear proliferation: legal (non-proliferation treaty (NPT), comprehensive nuclear test ban treaty (CTBT), fissile material cut off treaty (FMCT) etc..), technical (fabrication of fissile materials, delays). However, all these safeguards can be overcome as proven by the activities of some countries. The situation of proliferation for the other type of massive destruction weapons is presented too. (J.S.)

  10. An effective description of dark matter and dark energy in the mildly non-linear regime

    Energy Technology Data Exchange (ETDEWEB)

    Lewandowski, Matthew; Senatore, Leonardo [Stanford Institute for Theoretical Physics, Stanford University, Stanford, CA 94306 (United States); Maleknejad, Azadeh, E-mail: matthew.lewandowski@cea.fr, E-mail: azade@ipm.ir, E-mail: senatore@stanford.edu [School of Physics, Institute for Research in Fundamental Sciences (IPM), P. Code. 19538-33511, Tehran (Iran, Islamic Republic of)

    2017-05-01

    In the next few years, we are going to probe the low-redshift universe with unprecedented accuracy. Among the various fruits that this will bear, it will greatly improve our knowledge of the dynamics of dark energy, though for this there is a strong theoretical preference for a cosmological constant. We assume that dark energy is described by the so-called Effective Field Theory of Dark Energy, which assumes that dark energy is the Goldstone boson of time translations. Such a formalism makes it easy to ensure that our signatures are consistent with well-established principles of physics. Since most of the information resides at high wavenumbers, it is important to be able to make predictions at the highest wavenumber that is possible. The Effective Field Theory of Large-Scale Structure (EFTofLSS) is a theoretical framework that has allowed us to make accurate predictions in the mildly non-linear regime. In this paper, we derive the non-linear equations that extend the EFTofLSS to include the effect of dark energy both on the matter fields and on the biased tracers. For the specific case of clustering quintessence, we then perturbatively solve to cubic order the resulting non-linear equations and construct the one-loop power spectrum of the total density contrast.

  11. The new generation of nuclear submarines: in violation of the non proliferation treaty - Booklet No. 3, June 2000

    International Nuclear Information System (INIS)

    2000-06-01

    The Observatory of French nuclear weapons looks forwards to the elimination of nuclear weapons in conformity with the aims of the nuclear non-proliferation Treaty. The object of this booklet of the Observatory of French nuclear weapons about the program of new generation missile-launching nuclear submarines is to show the amplitude of this program that is going to mobilize considerable industrial resources and energies to the detriment of other security alternatives

  12. P44/WDR77 restricts the sensitivity of proliferating cells to TGFβ signaling

    Energy Technology Data Exchange (ETDEWEB)

    Yi, Pengfei [Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Road, Wuhan, Hubei 430022 (China); Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 (United States); Gao, Shen [Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 (United States); Gu, Zhongping [Department of Thoracic Surgery, Tangdu Hospital, Fourth Military Medical University, Xi’an 710038 (China); Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 (United States); Huang, Tao [Department of Breast and Thyroid Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefang Road, Wuhan, Hubei 430022 (China); Wang, Zhengxin, E-mail: zhenwang@mdanderson.org [Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030 (United States)

    2014-07-18

    Highlights: • P44/WDR77 causes proliferating cells to become non-responsive to TGFβ signaling. • P44/WDR77 down-regulates TβRII and TβR2 expression. • P44/WDR77 down-regulated TGFβ signaling correlates with lung tumorigenesis. - Abstract: We previously reported that a novel WD-40 domain-containing protein, p44/WDR77, drives quiescent epithelial cells to re-enter the cell cycle and plays an essential role for growth of lung and prostate cancer cells. Transforming growth factor beta (TGFβ) signaling is important in the maintenance of non-transformed cells in the quiescent or slowly cycling stage. However, both non-transformed proliferating cells and human cancer cells are non-responsive to endogenous TGFβ signaling. The mechanism by which proliferating cells become refractory to TGFβ inhibition is not well established. Here, we found that silencing p44/WDR77 increased cellular sensitivity to TGFβ signaling and that this was inversely correlated with decreased cell proliferation. Smad2 or 3 phosphorylation, TGFβ-mediated transcription, and TGFβ2 and TGFβ receptor type II (TβRII) expression were dramatically induced by silencing of p44/WDR77. These data support the hypothesis that p44/WDR77 down-regulates the expression of the TGFβ ligand and its receptor, thereby leading to a cellular non-response to TGFβ signaling. Finally, we found that p44/WDR77 expression was correlated with cell proliferation and decreased TGFβ signaling during lung tumorigenesis. Together, these results suggest that p44/WDR77 expression causes the non-sensitivity of proliferating cells to TGFβ signaling, thereby contributing to cellular proliferation during lung tumorigenesis.

  13. The international climate regime: towards consolidation collapse

    International Nuclear Information System (INIS)

    Berthaud, P.; Cavard, D.; Criqui, P.

    2003-10-01

    This article deals with the different modalities that exist to manage a problem of collective action in the field of climate negotiation. It uses two concepts of the International Political Economy (IPE): the concept of International Regime (IR) and the concept of Hegemony and / or Leadership. The course the international negotiation has taken between 1992 (Rio Convention) and march 2001 (the US rejection of the Kyoto Protocol of 1997) leads us, first, to question the conditions of existence as well as the viability of a non-hegemonic International Regime (Part One). Then, we discuss the perspectives for the 'post - Kyoto' era. After having examined the preferences of the three most active actors in the negotiation (USA, Europe, G77 + China) combined with the leadership capacities they possess, we identify three scenarios for the future: i) anarchy, ii) an international regime under the American hegemony, iii) an international regime under the European leadership (Part Two). (author)

  14. Preshot predictions for the near-source region in the non-proliferation experiment

    Energy Technology Data Exchange (ETDEWEB)

    Patch, D.F.; Welch, J.E.; Zerkle, J. [SAIC/Simulation Technology Operation, San Diego, CA (United States)

    1994-12-31

    This paper summarizes a number of one and two-dimensional, ground motion calculations made in support of the Non-Proliferation Experiment (NPE), a 1KT high explosive shot fired on 22 September 1993 at the Nevada Test Site. These calculations were sponsored by the Defense Nuclear Agency`s late-time containment program, and were completed well before the test was executed. They addressed a variety of test design, analysis and construction issues, and sought to identify any potential safety concerns. The test site model used in these calculations was based in large part on earlier work performed at SAIC and by other Defense Nuclear Agency (DNA) contractors for the nearby underground nuclear test, code named MISTY ECHO. In particular, to obtain physical property and quasi-static material response data for the site, a number of core samples recovered near the MISTY ECHO working point (WP) were tested by TerraTek. We then used these data to develop a numerical response model for the site.

  15. The metabolic regimes of flowing waters

    Science.gov (United States)

    Bernhardt, Emily S.; Heffernan, Jim B.; Grimm, Nancy B.; Stanley, Emily H.; Harvey, Judson; Arroita, M.; Appling, Alison; Cohen, M.J.; McDowell, William H.; Hall, R.O.; Read, Jordan S.; Roberts, B.J.; Stets, Edward; Yackulic, Charles B.

    2018-01-01

    The processes and biomass that characterize any ecosystem are fundamentally constrained by the total amount of energy that is either fixed within or delivered across its boundaries. Ultimately, ecosystems may be understood and classified by their rates of total and net productivity and by the seasonal patterns of photosynthesis and respiration. Such understanding is well developed for terrestrial and lentic ecosystems but our understanding of ecosystem phenology has lagged well behind for rivers. The proliferation of reliable and inexpensive sensors for monitoring dissolved oxygen and carbon dioxide is underpinning a revolution in our understanding of the ecosystem energetics of rivers. Here, we synthesize our current understanding of the drivers and constraints on river metabolism, and set out a research agenda aimed at characterizing, classifying and modeling the current and future metabolic regimes of flowing waters.

  16. Global proliferation concerns

    International Nuclear Information System (INIS)

    Simpkins, R.

    1978-01-01

    The Non-Proliferation Treaty and the IAGA Safeguards System are discussed. President Carter's program to defer commercial reprocessing and recycle, to restructure the breeder program, to develop alternative fuel cycles, to increase US uranium enrichment capability, to provide fuel assurance for consumer nations, to continue the embargo of sensitive technology and equipment and to develop the International Nuclear Fuel Cycle Evaluation Program is outlined

  17. Prospects for cooperation among the Eurasian Countries and the proliferation concerns of the West

    International Nuclear Information System (INIS)

    Kibaroglu, M.

    2001-01-01

    ) programme that was initiated by the United States as early as 1991. Beside these positive developments on the side of nuclear disarmament of two 'nuclear empires' now the threat of spread of nuclear weapons manufacturing capabilities (i.e., proliferation) to many other nations is becoming a serious concern of many governments as well as non-governmental organizations, big and small, all over the world. Dangers associated with nuclear proliferation is becoming much more frequently discussed in high level official meetings on many occasions. To cite one serious action, the so-called Programme 93+2 which was initiated in 1993 and terminated in late 1995 investigated the loopholes and shortcomings of the existing nuclear non-proliferation regime with special emphasis given to its centerpiece agreement, namely the Non-Proliferation Treaty (NPT) and its associated verification mechanism depicted in the IAEA document called INFCIRC/153. The resulting study gave way to the so-called Additional (Model) Protocol INFCIRC/540 by means of which inspections are said to become more intrusive than before. There is no wonder that with the reflex thoughts of the past, some circles in the West in general, and in the United States in particular, will try to cast doubt on the pace and the nature of relations between Turkey and the Eurasian countries. The unique characteristics of relations between Turkey and our friends in the Eurasian landscape may provoke unfounded speculations such as misusing the scientific as well as material accumulation in the nuclear field in the Eurasian countries since the Soviet times that can be made available to Turkey's alleged nuclear ambitions. However, one should not disregard the fact that responsible figures, be they in political and administrative circles, or be they in scientific circles, are in charge of, and involved in, nuclear research and development in all the parties concerned. Turkey's long standing formal membership to the NPT and the to IAEA as

  18. Information report on the behalf of the foreign affairs, defence and armed forces Commission on France security, nuclear disarmament and non proliferation; Rapport d'information fait au nom de la commission des affaires etrangeres, de la defense et des forces armees (1) sur le desarmement, la non-proliferation nucleaires et la securite de la France

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    This report first gives an overview of nuclear disarmament and non proliferation twenty years after the end of Cold War: evolution and status of Russia's and United States' nuclear weapon arsenals, France's and United Kingdom's trend to reduce their nuclear armament, reinforcement of China's nuclear armament, effects and limitations of the Non Proliferation Treaty (NPT). It notices that the new international context gave birth to some expectations and may lead to a lower nuclear pressure, notably with the influence of START negotiations between Russia and the United States, provided that the Comprehensive Nuclear Test Ban Treaty is ratified by more countries, and that negotiations promote a Fissile Material Cut-off Treaty. The report also outlines the importance of the promotion of better controlled peaceful uses of nuclear energy. It discusses the relationship between maintaining the world nuclear order and the reduction of international and regional tensions, and the importance of struggle against all forms of proliferation. It analyses the French nuclear posture in terms of security requirements, and in front of the zero nuclear option, in a context of ballistic missile proliferation, and in relationship with the issue of tactical nuclear weapons in Europe

  19. Non-disruptive regime changes-The case of competing energy efficient lighting trajectories

    DEFF Research Database (Denmark)

    Franceschini, Simone; Alkemade, Floortje

    2016-01-01

    Technologies within the same industry are expected to follow similar patterns of innovation, and when the dominant patterns change, this is often expected to have disruptive effects on the industry. However, the three most recent lighting technologies (fluorescent, compact fluorescent, and LED......) show different patterns of innovative activities despite similarities in the determinants of innovation; and we observed multiple technological regimes within the lighting industry. Furthermore, we observed changes in these innovative patterns without widespread disruptive effects. While FL and LED...... for policymakers in stimulating new technologies in industries with undesirable Mark II pattern through the influence of all the dimensions of the technological regimes....

  20. The nuclear spread: a third world view

    International Nuclear Information System (INIS)

    Kapur, A.

    1980-01-01

    The subject is discussed under the following sections: introduction to Non-Proliferation Treaty; background factors (context in which nuclear weapon states, non-nuclear weapon states and prominent hard-core potential proliferators must operate); the NPT constituency; proliferation factors for and against duality of decisions; vertical vs horizontal proliferation; implications for the NPT regime; a new approach; the 1980 agenda; regional security; the South Asian scene. (U.K.)

  1. Utility of Social Modeling for Proliferation Assessment - Preliminary Findings

    International Nuclear Information System (INIS)

    Coles, Garill A.; Gastelum, Zoe N.; Brothers, Alan J.; Thompson, Sandra E.

    2009-01-01

    Often the methodologies for assessing proliferation risk are focused around the inherent vulnerability of nuclear energy systems and associated safeguards. For example an accepted approach involves ways to measure the intrinsic and extrinsic barriers to potential proliferation. This paper describes preliminary investigation into non-traditional use of social and cultural information to improve proliferation assessment and advance the approach to assessing nuclear material diversion. Proliferation resistance assessment, safeguard assessments and related studies typically create technical information about the vulnerability of a nuclear energy system to diversion of nuclear material. The purpose of this research project is to find ways to integrate social information with technical information by explicitly considering the role of culture, groups and/or individuals to factors that impact the possibility of proliferation. When final, this work is expected to describe and demonstrate the utility of social science modeling in proliferation and proliferation risk assessments.

  2. JT-60U high performance regimes

    International Nuclear Information System (INIS)

    Ishida, S.

    1999-01-01

    High performance regimes of JT-60U plasmas are presented with an emphasis upon the results from the use of a semi-closed pumped divertor with W-shaped geometry. Plasma performance in transient and quasi steady states has been significantly improved in reversed shear and high- βp regimes. The reversed shear regime elevated an equivalent Q DT eq transiently up to 1.25 (n D (0)τ E T i (0)=8.6x10 20 m-3·s·keV) in a reactor-relevant thermonuclear dominant regime. Long sustainment of enhanced confinement with internal transport barriers (ITBs) with a fully non-inductive current drive in a reversed shear discharge was successfully demonstrated with LH wave injection. Performance sustainment has been extended in the high- bp regime with a high triangularity achieving a long sustainment of plasma conditions equivalent to Q DT eq ∼0.16 (n D (0)τ E T i (0)∼1.4x10 20 m -3 ·s·keV) for ∼4.5 s with a large non-inductive current drive fraction of 60-70% of the plasma current. Thermal and particle transport analyses show significant reduction of thermal and particle diffusivities around ITB resulting in a strong Er shear in the ITB region. The W-shaped divertor is effective for He ash exhaust demonstrating steady exhaust capability of τ He */τ E ∼3-10 in support of ITER. Suppression of neutral back flow and chemical sputtering effect have been observed while MARFE onset density is rather decreased. Negative-ion based neutral beam injection (N-NBI) experiments have created a clear H-mode transition. Enhanced ionization cross- section due to multi-step ionization processes was confirmed as theoretically predicted. A current density profile driven by N-NBI is measured in a good agreement with theoretical prediction. N-NBI induced TAE modes characterized as persistent and bursting oscillations have been observed from a low hot beta of h >∼0.1-0.2% without a significant loss of fast ions. (author)

  3. Printed Proliferation: The Implications of Additive Manufacturing and Nuclear Weapons Proliferation

    Energy Technology Data Exchange (ETDEWEB)

    Lindsey, Nicholas C. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-01-26

    The growth of additive manufacturing as a disruptive technology poses nuclear proliferation concerns worthy of serious consideration. Additive manufacturing began in the early 1980s with technological advances in polymer manipulation, computer capabilities, and computer-aided design (CAD) modeling. It was originally limited to rapid prototyping; however, it eventually developed into a complete means of production that has slowly penetrated the consumer market. Today, additive manufacturing machines can produce complex and unique items in a vast array of materials including plastics, metals, and ceramics. These capabilities have democratized the manufacturing industry, allowing almost anyone to produce items as simple as cup holders or as complex as jet fuel nozzles. Additive manufacturing, or three-dimensional (3D) printing as it is commonly called, relies on CAD files created or shared by individuals with additive manufacturing machines to produce a 3D object from a digital model. This sharing of files means that a 3D object can be scanned or rendered as a CAD model in one country, and then downloaded and printed in another country, allowing items to be shared globally without physically crossing borders. The sharing of CAD files online has been a challenging task for the export controls regime to manage over the years, and additive manufacturing could make these transfers more common. In this sense, additive manufacturing is a disruptive technology not only within the manufacturing industry but also within the nuclear nonproliferation world. This paper provides an overview of additive manufacturing concerns of proliferation.

  4. Nuclear experts and nuclear weapons proliferation

    International Nuclear Information System (INIS)

    Mueller, H.

    1979-01-01

    In Germany the issue of nuclear weapons proliferation has attracted scant attention. Most potential nuclear weapon states are important trade partners of the FRG and, since further proliferation of nuclear weapons could worsen conflicts involving these, it should be in the FRG's interest to limit proliferation. The security of the FRG is also dependent on the common interest of the great powers to avoid nuclear war. The contradictory positions of Usa and the USSR on nuclear weapons policy regarding themselves and non-nuclear weapon states encourages less developed countries to see nuclear weaponry as useful. The NPT and IAEA safeguards have only limited inhibiting effect. The nuclear export policy of the FRG has been dominated by short term economic advantage, neglecting the negative long term effects of decreased political stability. The FRG should formulate a policy based on self-restraint, positive stimuli and extension of controls, using its economic strength to deter proliferation. (JIW)

  5. Expression of TRIM28 correlates with proliferation and Bortezomib-induced apoptosis in B-cell non-Hodgkin lymphoma.

    Science.gov (United States)

    Zhang, Pei-Pei; Ding, Da-Zhi; Shi, Bing; Zhang, Shu-Qing; Gu, Ling-Li; Wang, Yu-Chan; Cheng, Chun

    2018-03-23

    Tripartite motif containing 28 (TRIM28) as a transcriptional co-repressor has been reported playing a role in regulating DNA damage response (DDR), cell differentiation, immune response, and tumorigenesis. The present study was performed to explore the biological function and clinical significance of TRIM28 in B-cell non-Hodgkin lymphoma (B-NHL). Results of the study displayed that high expression of TRIM28 was positively associated with the poorer survival of B-NHL patients as an independent prognostic factor. In addition, TRIM28 could promote the B-NHL cells proliferation through modulating cell cycle progression. The change of cyclinA, P21, and PCNA expression after TRIM28 expression modified further illustrated the mechanism in which TRIM28 participated in cell proliferation progression. Moreover, inhibition TRIM28 expression in B-NHL cells enhanced the sensibility to Bortezomib by regulating p53-mediated apoptosis pathway. Taken together, the present study showed that TRIM28 functions as a tumor promoter in B-NHL and may be a novel target for drug resistance to Bortezomib.

  6. A Study on the Nuclear Foreign Policy

    International Nuclear Information System (INIS)

    Lee, Byung Wook; Lee, H. M.; Ko, H. S.; Ryu, J. S.; Oh, K. B.; Yang, M. H.; Lee, K. S.

    2007-12-01

    This study approaches the international trends related to nuclear non-proliferation in four aspects. First, this study analyzes the trend of the international nuclear non-proliferation regime, which includes the Treaty on the Non-proliferation of Nuclear Weapons (NPT), the international nuclear export control regime and proposals for assurance of nuclear fuel supply. Second, this study analyzes the trend of international nuclear organizations, which includes the International Atomic Energy Agency (IAEA), a central body of development of nuclear technology and international nuclear diplomacy, and the Organization for Economic Co-operation and Development/Nuclear Energy Agency (OECD/NEA), a intergovernmental organization to consist of a group of nuclear advanced countries. Third, this study analyzes the trends of the U.S.'s nuclear foreign policies, particularly nuclear non-proliferation. Fourth, this study analyzes the nuclear issues of North Korea and Iran as they cause serious concerns to a international society

  7. A Study on the Nuclear Foreign Policy

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Byung Wook; Lee, H. M.; Ko, H. S.; Ryu, J. S.; Oh, K. B.; Yang, M. H.; Lee, K. S

    2007-12-15

    This study approaches the international trends related to nuclear non-proliferation in four aspects. First, this study analyzes the trend of the international nuclear non-proliferation regime, which includes the Treaty on the Non-proliferation of Nuclear Weapons (NPT), the international nuclear export control regime and proposals for assurance of nuclear fuel supply. Second, this study analyzes the trend of international nuclear organizations, which includes the International Atomic Energy Agency (IAEA), a central body of development of nuclear technology and international nuclear diplomacy, and the Organization for Economic Co-operation and Development/Nuclear Energy Agency (OECD/NEA), a intergovernmental organization to consist of a group of nuclear advanced countries. Third, this study analyzes the trends of the U.S.'s nuclear foreign policies, particularly nuclear non-proliferation. Fourth, this study analyzes the nuclear issues of North Korea and Iran as they cause serious concerns to a international society.

  8. Flow regimes

    International Nuclear Information System (INIS)

    Kh'yuitt, G.

    1980-01-01

    An introduction into the problem of two-phase flows is presented. Flow regimes arizing in two-phase flows are described, and classification of these regimes is given. Structures of vertical and horizontal two-phase flows and a method of their identification using regime maps are considered. The limits of this method application are discussed. The flooding phenomena and phenomena of direction change (flow reversal) of the flow and interrelation of these phenomena as well as transitions from slug regime to churn one and from churn one to annular one in vertical flows are described. Problems of phase transitions and equilibrium are discussed. Flow regimes in tubes where evaporating liquid is running, are described [ru

  9. Non proliferation and disarmament: nuclear disarmament and security policies in Sweden (1946-1975) - Historical note

    International Nuclear Information System (INIS)

    Hautecouverture, Benjamin

    2007-06-01

    The author first outlines that Sweden appeared during the Cold War as committed against nuclear weapons, but in fact concentrated this commitment on the objective of nuclear disarmament of nuclear countries without having a very clear position on the objective of non proliferation as it was defined at the end of the 1950's, and also maintained a (secret for while) military nuclear programme which has been progressively given up from the middle of the 1960's. Then, the author discusses why Sweden adopted this double posture, its effects on the international scene, and achievements and setbacks of the Swedish diplomacy with respect to disarmament until the first NPT review conference of 1975

  10. Molecular imaging of proliferation with [{sup 18}F]FLT-PET; Molekulare Bildgebung der Proliferation mit [{sup 18}F]FLT-PET

    Energy Technology Data Exchange (ETDEWEB)

    Buck, A.K.; Herrmann, K.; Schwaiger, M.; Wester, H.J. [Klinikum rechts der Isar, Technische Univ. Muenchen (Germany). Nuklearmedizinische Klinik und Poliklinik; Dechow, T.; Graf, N. [Klinikum rechts der Isar, Technische Univ. Muenchen (Germany). Medizinische Klinik III, Haematologi/Onkologie

    2009-06-15

    An increased proliferation fraction is a hallmark of malignant cells and a specific feature of malignant tumors which potentially allows more specific tumor imaging compared to increased glucose consumption (FDG-PET). The majority of therapeutic approaches aim at inhibition of proliferation or induction of apoptosis. Accordingly, non-invasive assessment of the proliferation fraction is also of interest for monitoring response to treatment and to early detect resistance to a specific kind of therapy. In clinical studies it has been demonstrated that the radiotracer 3'-deoxy-3'-[{sup 18}F]fluorothymidine (FLT) accumulates specifically in malignant tumors. Regression analysis of tumoral FLT-uptake and immunohistochemically detected proliferation fraction (PCNA, Ki-67) resulted in a significant correlation (e.g., in lung cancer, correlation coefficient r=0.87, p<0.0001). The possibility to non-invasively assess the proliferation fraction with FLT-PET has been shown in a variety of solid cancers. Compared to the standard radiotracer FDG, superior demonstration of the proliferative activity using FLT as the tracer has been demonstrated. On the other hand, accumulation of FLT was significantly lower compared to FDG. Malignant tumors with low proliferation rates did not present with increased FLT-uptake resulting in a reduced sensitivity. In lung cancer for example, the sensitivity was 86% of FLT-PET compared to 100% of FDG-PET. Also, regarding detection of locoregional lymph node metastases or distant metastases, FDG-PET was shown to have a higher sensitivity. Due to the reduced sensitivity, there is no advantage of specific imaging of tumor proliferation regarding tumor staging. In malignant lymphoma, FLT was similar effective for tumor staging as compared to FDG-PET. In a pilot study comprising 34 patients, both tracers showed a similar sensitivity regarding detection of lymphoma. An observed specificity of 100% indicates that FLT-PET represents a diagnostic

  11. Abstracts of reports of the International conference on non-proliferation problems

    International Nuclear Information System (INIS)

    Koltysheva, G.I.; Perepelkin, I.G.

    1997-01-01

    On August 21, 1947, the USSR Council of Ministers made a decision on creating Semipalatinsk Nuclear Test Site (STS). The first Nuclear Test on the Test Site was conducted on August 29, 1949, the last one was made on October 19, 1989. In all during 40 years on Semipalatinsk Test Site 116 ground and air and 340 underground nuclear tests were conducted. They brought much damage to health and lives of thousands of people who involuntarily participated in those events. On August 29, 1991, by Kazakstan President's decree STS was closed but the problems of people's rehabilitation, natural landscapes recovering, test-site infrastructure conversion remained. These problems are being solved under direct state programs, intergovernmental agreements of Kazakstan with Russia and the USA, cooperation with different international and foreign organizations, enterprises, scientific-research centers. Kazakstan subsequently constantly pursues the policy of nonproliferation, takes measures on ellimination of nuclear tests consequences and relative infrastructure. The Republic is not involved into military nuclear programs. From its territory all the nuclear weapon was taken away. Kazakstan joined the Agreement on Non-proliferation, signed the Agreement on Safeguards to all Nuclear activity on Kazakh territory with the IAEA

  12. Information report on the behalf of the Commission for Foreign Affairs, Defence and Armed Forces on nuclear proliferation - Nr 338

    International Nuclear Information System (INIS)

    Villepin, Xavier de

    2004-01-01

    Based on hearings of experts (notably MR El Baradei, IAEA general manager), and written at the time North Korea admitted the existence of a military nuclear programme and decided to expel IAEA inspectors, and Libya and Iran revealed nuclear activities which had been until then unsuspected, this report aims at discussing events which occurred during the two previous years in relationship with nuclear proliferation. The author first tries to draw some lessons from these recent proliferation crises. In this respect, he outlines that they reveal weaknesses of the international regime of nuclear non proliferation: lack of control means for the NPT, lack of control of the access to fuel cycle technologies, gaps in export controls exacerbated by the emergence of private actors. The author then highlights some dangerous features which threaten international safety: loss of credibility of the NPT as shown by North Korea withdrawing from the NPT without unbearable political cost, current crises with Iran and North Korea having a very strong destabilisation potential, and, with the threat of use of dirty bombs, emergence of relationships between proliferation and terrorism. In the next part, the author discusses how to make the struggle against nuclear proliferation more efficient: need of stronger mobilisation and unity within the international community, solution of the Iranian problem as a priority and a test for the international community, and ways to strengthen this struggle (implementation of additional protocols, necessity of an international framework for the control of activities related to the fuel cycle, and necessity of more visible sanctions for the sake and respect of treaties). Hearings and commission discussions are transcribed and proposed after this report

  13. ACCESSORIES OF FISCAL OBLIGATION. LEGAL REGIME

    Directory of Open Access Journals (Sweden)

    RADA POSTOLACHE

    2012-05-01

    Full Text Available The interest – which is an institution typical to private law, has been taken over by the fiscal field and adapted to the specific features of fiscal obligation – being defined by its imperative legal regime, which has at the least the following characteristic elements: unitary character, imposed legal percentage, compulsory demand of interest, automatic application. In order to render responsible fiscal debtors, the lawmaker has reintroduced, as an accessory of fiscal obligation, delayed payment penalties, which have a distinct nature and legal regime, but without the principle non bis in idem being transgressed. Our study aims to establish the legal regime ofaccessories typical to fiscal obligation, from the perspective of special normative acts, but also of the common law within the field – Civil Code and Government Ordinance No. 13/2011 – by pointing out at the same time both the particular circumstances and procedural ones regulated by the Fiscal Procedure Code, shedding light upon the controversial legal nature of accessories.

  14. Long non-coding RNA ANRIL is up-regulated in bladder cancer and regulates bladder cancer cell proliferation and apoptosis through the intrinsic pathway

    International Nuclear Information System (INIS)

    Zhu, Hongxue; Li, Xuechao; Song, Yarong; Zhang, Peng; Xiao, Yajun; Xing, Yifei

    2015-01-01

    Antisense non-coding RNA in the INK4 locus (ANRIL) is a member of long non-coding RNAs and has been reported to be dysregulated in several human cancers. However, the role of ANRIL in bladder cancer remains unclear. This present study aimed to investigate whether and how ANRIL involved in bladder cancer. Our results showed up-regulation of ANRIL in bladder cancer tissues versus the corresponding adjacent non-tumor tissues. To explore the specific mechanisms, ANRIL was silenced by small interfering RNA or short hairpin RNA transfection in human bladder cancer T24 and EJ cells. Knockdown of ANRIL repressed cell proliferation and increased cell apoptosis, along with decreased expression of Bcl-2 and increased expressions of Bax, cytoplasmic cytochrome c and Smac and cleaved caspase-9, caspase-3 and PARP. However, no change of cleaved caspase-8 level was observed. Furthermore, in vivo experiment confirmed that knockdown of ANRIL inhibited tumorigenic ability of EJ cells in nude mice. Meanwhile, in accordance with in vitro study, knockdown of ANRIL inhibited expression of Bcl-2 and up-regulated expressions of Bax and cleaved caspase-9, but did not affect cleaved caspase-8 level. In conclusion, we first report that ANRIL possibly serves as an oncogene in bladder cancer and regulates bladder cancer cell proliferation and apoptosis through the intrinsic apoptosis pathway. - Highlights: • We first report the role of ANRIL in bladder cancer. • ANRIL is obviously up-regulated in bladder cancer tissues. • ANRIL regulates bladder cancer cell proliferation and cell apoptosis through the intrinsic pathway.

  15. Functioning of spontaneous and induced Con A regulators of T-cell proliferation. Modifying factors

    International Nuclear Information System (INIS)

    Kuz'mina, E.G.

    1989-01-01

    It is shown that active spontaneous non-specific regulators of T-cell proliferation are activated in peripheral blood ''in vivo'' by endogenous metabolites; non-specific regulator action can be induced ''in vitro'' by Con A, FGA. Non-specific regulators suppress and increase lymphocyte proliferation. Cyclic character of their functioning is revealed. 4 refs.; 1 tab

  16. IAEA safeguards: Stemming the spread of nuclear weapons. As the world's nuclear inspectorate, the IAEA performs an indispensable role in furthering nuclear non-proliferation

    International Nuclear Information System (INIS)

    2002-01-01

    Following the completion of the Treaty on the Non- Proliferation of Nuclear Weapons (NPT) in 1968, the IAEA has become the instrument with which to verify that the peaceful use commitments made under the NPT or similar agreements are kept through performing what is known as its safeguards role. Under the NPT, governments around the world have committed to three common objectives: preventing the proliferation of nuclear weapons; pursuing nuclear disarmament; and promoting the peaceful uses of nuclear energy. The NPT has made it obligatory for all its non-nuclear weapon State parties to submit all nuclear material in nuclear activities to IAEA safeguards, and to conclude a comprehensive safeguards agreement with the Agency. With all but a handful of the world community as State parties, the NPT is by far the most widely adhered to legal agreement in the field of disarmament and non-proliferation. The IAEA takes account of all source and special fissionable material in countries under safeguards. Monitoring and verification activities focus on those types of nuclear material that are the most crucial and relevant to nuclear weapons manufacturing. This includes plutonium-239, uranium-233 and -235 and any material containing one or more of these. Safeguards activities are applied routinely at over 900 facilities in 71 countries. In 2001 alone, more than 21,000 calendar days in the field were devoted to verifying hundreds of tons of special fissionable material by more than IAEA 250 inspectors

  17. Emerging nuclear energy systems and nuclear weapon proliferation

    International Nuclear Information System (INIS)

    Gsponer, A.; Sahin, S.; Jasani, B.

    1983-01-01

    Generally when considering problems of proliferation of nuclear weapons, discussions are focused on horizontal proliferation. However, the emerging nuclear energy systems currently have an impact mainly on vertical proliferation. The paper indicates that technologies connected with emerging nuclear energy systems, such as fusion reactors and accelerators, enhance the knowledge of thermonuclear weapon physics and will enable production of military useful nuclear materials (including some rare elements). At present such technologies are enhancing the arsenal of the nuclear weapon states. But one should not forget the future implications for horizontal proliferation of nuclear weapons as some of the techniques will in the near future be within the technological and economic capabilities of non-nuclear weapon states. Some of these systems are not under any international control. (orig.) [de

  18. Transition to ballistic regime for heat transport in helium II

    Energy Technology Data Exchange (ETDEWEB)

    Sciacca, Michele, E-mail: michele.sciacca@unipa.it [Dipartimento Scienze Agrarie e Forestali, Università degli studi di Palermo, Viale delle Scienze, 90128 Palermo (Italy); Departament de Física, Universitat Autònoma de Barcelona, 08193 Bellaterra, Catalonia (Spain); Sellitto, Antonio, E-mail: ant.sellitto@gmail.com [Dipartimento di Matematica, Informatica ed Economia, Università della Basilicata, Campus Macchia Romana, 85100 Potenza (Italy); Jou, David, E-mail: david.jou@uab.cat [Departament de Física, Universitat Autònoma de Barcelona, 08193 Bellaterra, Catalonia (Spain); Institut d' Estudis Catalans, Carme 47, 08001 Barcelona, Catalonia (Spain)

    2014-07-04

    The size-dependent and flux-dependent effective thermal conductivity of narrow capillaries filled with superfluid helium is analyzed from a thermodynamic continuum perspective. The classical Landau evaluation of the effective thermal conductivity of quiescent superfluid, or the Gorter–Mellinck regime of turbulent superfluids, is extended to describe the transition to ballistic regime in narrow channels wherein the radius R is comparable to (or smaller than) the phonon mean-free path ℓ in superfluid helium. To do so, we start from an extended equation for the heat flux incorporating non-local terms, and take into consideration a heat slip flow along the walls of the tube. This leads from an effective thermal conductivity proportional to R{sup 2} (Landau regime) to another one proportional to Rℓ (ballistic regime). We consider two kinds of flows: along cylindrical pipes and along two infinite parallel plates. - Highlights: • Heat transport in counterflow helium in the ballistic regime. • The one-fluid model based on the Extended Thermodynamics is used. • The transition from the Landau regime to the ballistic regime. • The transition from quantum turbulence to ballistic regime.

  19. Nuclear proliferation and the near-nuclear countries

    International Nuclear Information System (INIS)

    Marwah, O.; Schulz, A.

    1975-01-01

    The process of nuclear proliferation and its consequences for the international political system is examined by focusing on the issues in the nuclear-strategic debate that divide first and second order states. Information is included on: the US-USSR arms race; SALT agreement; the Non-Proliferation Treaty; the nuclear aspirations and policies of India, Middle Eastern countries, South Africa, Japan, Brazil, and Argentina; and assessment of the risks related to the nuclear fuel cycle and nuclear weapons

  20. Peroxisome proliferator-activated receptor α (PPARα mRNA expression in human hepatocellular carcinoma tissue and non-cancerous liver tissue

    Directory of Open Access Journals (Sweden)

    Kurokawa Tsuyoshi

    2011-12-01

    Full Text Available Abstract Background Peroxisome proliferator-activated receptor α (PPARα regulates lipid metabolism in the liver. It is unclear, however, how this receptor changes in liver cancer tissue. On the other hand, mouse carcinogenicity studies showed that PPARα is necessary for the development of liver cancer induced by peroxisome proliferators, and the relationship between PPARα and the development of liver cancer have been the focus of considerable attention. There have been no reports, however, demonstrating that PPARα is involved in the development of human liver cancer. Methods The subjects were 10 patients who underwent hepatectomy for hepatocellular carcinoma. We assessed the expression of PPARα mRNA in human hepatocellular carcinoma tissue and non-cancerous tissue, as well as the expression of target genes of PPARα, carnitine palmitoyltransferase 1A and cyclin D1 mRNAs. We also evaluated glyceraldehyde 3-phosphate dehydrogenase, a key enzyme in the glycolytic system. Results The amounts of PPARα, carnitine palmitoyltransferase 1A and glyceraldehyde 3-phosphate dehydrogenase mRNA in cancerous sections were significantly increased compared to those in non-cancerous sections. The level of cyclin D1 mRNA tends to be higher in cancerous than non-cancerous sections. Although there was a significant correlation between the levels of PPARα mRNA and cyclin D1 mRNA in both sections, however the correlation was higher in cancerous sections. Conclusion The present investigation indicated increased expression of PPARα mRNA and mRNAs for PPARα target genes in human hepatocellular carcinoma. These results might be associated with its carcinogenesis and characteristic features of energy production.

  1. Modern fire regime resembles historical fire regime in a ponderosa pine forest on Native American land

    Science.gov (United States)

    Amanda B. Stan; Peter Z. Fule; Kathryn B. Ireland; Jamie S. Sanderlin

    2014-01-01

    Forests on tribal lands in the western United States have seen the return of low-intensity surface fires for several decades longer than forests on non-tribal lands. We examined the surface fire regime in a ponderosa pinedominated (Pinus ponderosa) forest on the Hualapai tribal lands in the south-western United States. Using fire-scarred trees, we inferred temporal (...

  2. Proceedings of the symposium on the Non-Proliferation Experiment (NPE): Results and implications for test ban treaties

    Energy Technology Data Exchange (ETDEWEB)

    Denny, M.D.; Stull, S.P. [eds.

    1994-12-31

    The large amounts of chemical explosives used worldwide in mining, quarrying, and civil engineering projects presents a challenge for policy makers molding a test ban, since their use could provide the necessary cover for a clandestine nuclear test. The Non-Proliferation Experiment (NPE) seeks to measure certain differences between an underground nuclear test and a chemical explosion in the same geology. Two chemical explosions were detonated at the Nevada Test Site to compare their signatures with previous nuclear tests. This conference presents results of these tests and discusses implications for test ban treaties. Conference papers are divided into the following sections: Background; Test preparations; EOS and code simulations; Rainier Mesa structure; Ground motion measurements; Non-seismic technologies; On-site inspection technologies; and a panel discussion. Selected papers are indexed separately for inclusion in the Energy Science and Technology Database.

  3. Nuclear commerce and non-proliferation in the 1980's: some thoughst

    International Nuclear Information System (INIS)

    Smith, G.

    1982-01-01

    The spread of nuclear technology and the possibility of nuclear proliferation were discussed. The United States foreign policies on these topics, and their effects on the nuclear power industry, were also included

  4. Environmental sampling: Issues for the cut-off regime

    International Nuclear Information System (INIS)

    Fearey, B.L.

    1995-01-01

    The fissile material cut-off treaty (FMCT) initiative under the Conference on Disarmament mandate is envisioned to include certain aspects of environmental sampling and monitoring. One of the intents of this treaty is to bring certain non-NPT signatories (e.g., threshold states) under this treaty agreement along with the nuclear weapon states (NWSs). This paper provides a brief overview of some of the relevant issues that may be involved in the implementation and use of environmental monitoring for (1) verification of the cut-off regime declarations, (2) the detection of undeclared activities, and, (3) application in non-routine inspections. The intent is to provide backstopping information important for treaty negotiators. Specific issues addressed within this paper include signature sampling, differences in the proposed detection regime, potential signature integrators, specific examples and spoofing concerns. Many of these issues must be carefully considered and weighed in order to create a credibly verifiable inspection regime. Importantly, the cut-off treaty must enable nondiscriminatory implementation, while carefully assuring that nonproliferation treaty requirements are maintained (i.e., preventing unintentional release of critical weapons design information--potentially through environmental sampling and analysis)

  5. Human tumor cell proliferation evaluated using manganese-enhanced MRI.

    Directory of Open Access Journals (Sweden)

    Rod D Braun

    Full Text Available Tumor cell proliferation can depend on calcium entry across the cell membrane. As a first step toward the development of a non-invasive test of the extent of tumor cell proliferation in vivo, we tested the hypothesis that tumor cell uptake of a calcium surrogate, Mn(2+ [measured with manganese-enhanced MRI (MEMRI], is linked to proliferation rate in vitro.Proliferation rates were determined in vitro in three different human tumor cell lines: C918 and OCM-1 human uveal melanomas and PC-3 prostate carcinoma. Cells growing at different average proliferation rates were exposed to 1 mM MnCl(2 for one hour and then thoroughly washed. MEMRI R(1 values (longitudinal relaxation rates, which have a positive linear relationship with Mn(2+ concentration, were then determined from cell pellets. Cell cycle distributions were determined using propidium iodide staining and flow cytometry. All three lines showed Mn(2+-induced increases in R(1 compared to cells not exposed to Mn(2+. C918 and PC-3 cells each showed a significant, positive correlation between MEMRI R(1 values and proliferation rate (p≤0.005, while OCM-1 cells showed no significant correlation. Preliminary, general modeling of these positive relationships suggested that pellet R(1 for the PC-3 cells, but not for the C918 cells, could be adequately described by simply accounting for changes in the distribution of the cell cycle-dependent subpopulations in the pellet.These data clearly demonstrate the tumor-cell dependent nature of the relationship between proliferation and calcium influx, and underscore the usefulness of MEMRI as a non-invasive method for investigating this link. MEMRI is applicable to study tumors in vivo, and the present results raise the possibility of evaluating proliferation parameters of some tumor types in vivo using MEMRI.

  6. Nuclear dilemma: power, proliferation, and development

    International Nuclear Information System (INIS)

    Miller, M.

    1979-01-01

    Debate over President Carter's nuclear energy policy centers on how to develop nuclear power for civilian use and prevent the proliferation of nuclear materials for weapons. Both supporters and opponents of nuclear energy have been critical of Carter's policies because each side fails to see the linkage between the two concerns as codified in the 1978 Non-Proliferation Act. The author uses a dialogue format to illustrate the arguments for resisting proliferation and recognizing nuclear energy as an appropriate technology. The consequences of a nuclear moratorium are explored along with implications for foreign policy. U.S. leadership in developing energy technologies that can meet a broad range of appropriate applications, combined with leadership in building appropriate political frameworks, is needed if nuclear energy is to make a positive contribution toward world peace and acceptable living standards. 8 references

  7. An improved particle population balance equation in the continuum-slip regime

    Directory of Open Access Journals (Sweden)

    Xie Mingliang

    2016-01-01

    Full Text Available An improved moment model is proposed to solve the population balance equation for Brownian coagulation in the continuum-slip regime, and it reduces to a known one in open literature when the non-linear terms in the slip correction factor are ignored. The present model shows same asymptotic behavior as that in the continuum regime.

  8. Non-linear dynamical classification of short time series of the rössler system in high noise regimes.

    Science.gov (United States)

    Lainscsek, Claudia; Weyhenmeyer, Jonathan; Hernandez, Manuel E; Poizner, Howard; Sejnowski, Terrence J

    2013-01-01

    Time series analysis with delay differential equations (DDEs) reveals non-linear properties of the underlying dynamical system and can serve as a non-linear time-domain classification tool. Here global DDE models were used to analyze short segments of simulated time series from a known dynamical system, the Rössler system, in high noise regimes. In a companion paper, we apply the DDE model developed here to classify short segments of encephalographic (EEG) data recorded from patients with Parkinson's disease and healthy subjects. Nine simulated subjects in each of two distinct classes were generated by varying the bifurcation parameter b and keeping the other two parameters (a and c) of the Rössler system fixed. All choices of b were in the chaotic parameter range. We diluted the simulated data using white noise ranging from 10 to -30 dB signal-to-noise ratios (SNR). Structure selection was supervised by selecting the number of terms, delays, and order of non-linearity of the model DDE model that best linearly separated the two classes of data. The distances d from the linear dividing hyperplane was then used to assess the classification performance by computing the area A' under the ROC curve. The selected model was tested on untrained data using repeated random sub-sampling validation. DDEs were able to accurately distinguish the two dynamical conditions, and moreover, to quantify the changes in the dynamics. There was a significant correlation between the dynamical bifurcation parameter b of the simulated data and the classification parameter d from our analysis. This correlation still held for new simulated subjects with new dynamical parameters selected from each of the two dynamical regimes. Furthermore, the correlation was robust to added noise, being significant even when the noise was greater than the signal. We conclude that DDE models may be used as a generalizable and reliable classification tool for even small segments of noisy data.

  9. Nuclear non-proliferation and security culture within EDF nuclear fleet

    International Nuclear Information System (INIS)

    Debes, M.

    2013-01-01

    This document describes the nuclear non-proliferation strategy and the safety culture of EDF. The author lists all the mandatory rules and regulations at international and national levels EDF has to comply with. All these requirements are applied in EDF nuclear facilities through adequate procedures that assure a nuclear material accountancy, a follow-up of any item containing nuclear material in the facility, and internal controls. External independent controls are also performed. The EDF security policy goal is to protect human, material and knowledge assets, and to preserve operational capacity, competitiveness and public confidence, within national regulatory framework and regulation on 'vital importance facilities'. The treatment of events or incident (detection, analysis, lessons drawn, experience feedback) is a tool to progress, along with reporting, internal control process and audits. The security requirements cover the different related domains important to EDF industrial assets: security of employees against assaults; security of data according to their sensibility level; security of the information system and telecom; awareness and training of employees; relations with external suppliers or contractors; business premises; security of staff and projects abroad. For industrial facilities and grids (facilities of 'vital importance'...), the defense in depth principles are applied against the different threat scenarios. Security measures are studied at the design stage in a consistent way with nuclear safety measures, while taking into account the protective means deployed by public authorities. These risk analysis are periodically reassessed. The paper is followed by the slides of the presentation. (A.C.)

  10. Introduction of Counter-Proliferation Capabilities in Development States

    International Nuclear Information System (INIS)

    Caulfield, P.; Edwards, T.; Witkin, A.; Elgebaly, A.

    2010-01-01

    In recent history we have seen a number of States develop their indigenous industrial skills to a point suitable for the manufacture of nuclear components. Private individuals unbeknown to the State have then utilized this capability to supply directly into proliferation networks - potentially reducing international confidence in such a State. To combat this possibility, a developing State must recognize the challenges that are raised by its emerging skills and take action to introduce measures that not only help the State identify proliferation activities but also ensure the national security of the State. One of those measures might be to develop a capability within the State to recognize and counter the activities of would-be-proliferators. In many States this capability is managed and applied through a dedicated counter-proliferation unit that has strong links with border controls and customs organizations. A counter-proliferation unit, once established could show dramatic returns for a modest investment. The activities of such a Unit could save the State political embarrassment by hindering and narrowing the chances of unintentional proliferation activities. The Unit should not be introduced as part of a Safeguards agreement or as part of a non proliferation treaty. It should rather be established as an act by the State to protect and control its emerging technologies from being involved, willingly or unwittingly, in proliferation activities. This is a sovereign act of the State - solely for its benefit and should not be imposed by any external power. Today's would-be-proliferators around the world cooperate and act together; similarly emerging counter-proliferation units should act and work together in order to be a step ahead of the proliferators. Improved world-wide cooperation should increase the detection rate of proliferation incidents which will in turn curtail the spread of nuclear weapons - for the benefit of all. (author)

  11. Legitimacy, capability, effectiveness and the future of the NPT

    International Nuclear Information System (INIS)

    Keeley, J.F.

    1987-01-01

    This chapter looks at the relationship between legitimacy and capability in conceptually and politically contestable regions. This issue was highlighted by India's nuclear test of May 1974 and the Osiraq raid of 1981. These illustrated the general problem of the threat to the coherence and legitimacy of the non-proliferation regime. This threat arose from the spread of nuclear technological capabilities. Two developments in the non-proliferation regime that have helped produce the more specific problems of that regime are discussed. These are the spread of nuclear technological capabilities and the development of complex co-operation networks. The prospects for the modification of the NPT in response to these challenges are considered finally. (U.K.)

  12. Finite Volume Method for Pricing European Call Option with Regime-switching Volatility

    Science.gov (United States)

    Lista Tauryawati, Mey; Imron, Chairul; Putri, Endah RM

    2018-03-01

    In this paper, we present a finite volume method for pricing European call option using Black-Scholes equation with regime-switching volatility. In the first step, we formulate the Black-Scholes equations with regime-switching volatility. we use a finite volume method based on fitted finite volume with spatial discretization and an implicit time stepping technique for the case. We show that the regime-switching scheme can revert to the non-switching Black Scholes equation, both in theoretical evidence and numerical simulations.

  13. China and the post-cold-war nuclear world

    International Nuclear Information System (INIS)

    Nakatsuji, Keiji

    1997-01-01

    On May 15, 1995, only a few days after the indefinite extension of the Non-Proliferation Treaty, China tested a nuclear bomb. The rapid growth in China's defence spending is also alarming. Against the spirit of international non-proliferation regimes, China has sold missile components to Pakistan, a research reactor and an electromagnetic isotope separation facility to Iran. In addition to the repression of human rights domestically, in China as well as in Tibet, no one can ignore the possibility of a serious international conflict over the Spratly Islands. This paper examines whether China will pose a grave future threat to world peace or whether, fearing international isolation, it will become a guardian of the international non-proliferation regime. In other words, the paper aims to set straight the record of China's recent nuclear policy

  14. Nuclear proliferation and civilian nuclear power. Report of the Nonproliferation Alternative Systems Assessment Program. Volume VII. International perspectives

    Energy Technology Data Exchange (ETDEWEB)

    1980-06-01

    The purpose of this volume is to assess the proliferation vulnerabilities of the present deployment of civilian nuclear-power systems within the current nonproliferation regime and, in light of their prospective deployment, to consider technical and institutional measures and alternatives which may contribute to an improved regime in which nuclear power could play a significant part. An assessment of these measures must include consideration of their nonproliferation effectiveness as well as their bearing upon energy security, and their operational, economic, and political implications. The nature of these considerations can provide some measure of their likely acceptability to various nations.

  15. Nuclear proliferation and civilian nuclear power. Report of the Nonproliferation Alternative Systems Assessment Program. Volume VII. International perspectives

    International Nuclear Information System (INIS)

    1980-06-01

    The purpose of this volume is to assess the proliferation vulnerabilities of the present deployment of civilian nuclear-power systems within the current nonproliferation regime and, in light of their prospective deployment, to consider technical and institutional measures and alternatives which may contribute to an improved regime in which nuclear power could play a significant part. An assessment of these measures must include consideration of their nonproliferation effectiveness as well as their bearing upon energy security, and their operational, economic, and political implications. The nature of these considerations can provide some measure of their likely acceptability to various nations

  16. Nuclear war nuclear proliferation and their consequences

    International Nuclear Information System (INIS)

    Aga Khan, Sadruddin

    1986-01-01

    The paper concerns the proceedings of a conference hosted by the Groupe de Bellerive to explore and discuss the implications for humanity of nuclear war, nuclear proliferation and their consequences, Geneva 1985. The conference was divided into five sessions, headed by the subject titles: the nuclear non-proliferation treaty (NPT) and its future, the spread of nuclear weapons among nations, global effects of a nuclear war, the nuclear arms race and arms control, the NPT and its future. Twenty eight papers were presented in the five sessions. (UK)

  17. Monetary Regimes and External Shocks Reaction: Empirical Investigations on Eastern European Economies

    Directory of Open Access Journals (Sweden)

    Muhammad Khan

    2017-12-01

    Full Text Available In the late 90's, after severe financial crisis, accompanied by inflation and exchange rate instability, Eastern Europe emerged into two radically contrasting monetary regimes (Currency Boards and Inflation targeting. The task of our study is to compare econometrically the performance of these two regimes in terms of their resilience to the external real and nominal shocks, coming from Euro area. In other words, we test the non-neutrality of exchange rate regimes with respect to these connections. Our PVAR model results reveal that the choice of monetary regimes indeed determines the ability of a country to absorb the external shocks.

  18. An Introduction to The Interdisciplinary Concept of Risk-Informed Proliferation Resistance

    International Nuclear Information System (INIS)

    Gouveia, Fernando

    2010-01-01

    The nonproliferation community is rich in diverse attempts aimed at predicting and preventing attempts at nuclear proliferation. Such efforts, however, are rarely incorporated into a holistic approach well-suited to solving both existing and emerging proliferation dilemmas. This division is particularly apparent with respect to the partition that separates the socio-political and technical approaches to solving such problems, approaches which are very often developed and utilized in isolation. Complicating matters further, are the diverse positions taken by various entities as they relate to the secure implementation of nuclear energy world-wide. Such positions range from the obdurate belief in the supposed inherent proliferation resistance of traditional spent fuel, to those regarding all nuclear energy systems as inherently proliferation prone, given their core reliance on the sensitive technologies of enrichment and reprocessing. Accordingly, moderates have argued for a risk-informed approach to combat nuclear proliferation, combining institutional factors, such as IAEA safeguards, with innovative reactor and fuel designs to bring about an acceptable notion of proliferation resistance. To this end, methodologies have been developed, which seek to assess and score attained proliferation resistance. Most notably, these include, the Proliferation Resistance and Physical Protection (PR and PP) methodology prepared by the GEN-IV International Forum and the IAEA's International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO). Such approaches have greatly advanced the concept of proliferation resistance; however, they remain limited by their exclusive concentration on the technological determinants of proliferation and non-consideration of other, equally important, socio-political determinants. This limitation is significant as numerous incidents have illustrated the ability of atypical states to find alternate paths to proliferation, for example

  19. The evolution, etiology and eventualities of the global health security regime.

    Science.gov (United States)

    Hoffman, Steven J

    2010-11-01

    Attention to global health security governance is more important now than ever before. Scientists predict that a possible influenza pandemic could affect 1.5 billion people, cause up to 150 million deaths and leave US$3 trillion in economic damages. A public health emergency in one country is now only hours away from affecting many others. Using regime analysis from political science, the principles, norms, rules and decision-making procedures by which states govern health security are examined in the historical context of their punctuated evolution. This methodology illuminates the catalytic agents of change, distributional consequences and possible future orders that can help to better inform progress in this area. Four periods of global health security governance are identified. The first is characterized by unilateral quarantine regulations (1377-1851), the second by multiple sanitary conferences (1851-92), the third by several international sanitary conventions and international health organizations (1892-1946) and the fourth by the hegemonic leadership of the World Health Organization (1946-????). This final regime, like others before it, is challenged by globalization (e.g. limitations of the new International Health Regulations), changing diplomacy (e.g. proliferation of global health security organizations), new tools (e.g. global health law, human rights and health diplomacy) and shock-activated vulnerabilities (e.g. bioterrorism and avian/swine influenza). This understanding, in turn, allows us to appreciate the impact of this evolving regime on class, race and gender, as well as to consider four possible future configurations of power, including greater authority for the World Health Organization, a concert of powers, developing countries and civil society organizations. This regime analysis allows us to understand the evolution, etiology and eventualities of the global health security regime, which is essential for national and international health

  20. The simulation of stationary and non-stationary regime operation of heavy water production facilities

    International Nuclear Information System (INIS)

    Peculea, M.; Beca, T.; Constantinescu, D.M.; Dumitrescu, M.; Dimulescu, A.; Isbasescu, G.; Stefanescu, I.; Mihai, M.; Dogaru, C.; Marinescu, M.; Olariu, S.; Constantin, T.; Necula, A.

    1995-01-01

    This paper refers to testing procedures of the production capacity of heavy water production pilot, industrial scale plants and of heavy water reconcentration facilities. Simulation codes taking into account the mass and heat transfers inside the exchange columns were developed. These codes provided valuable insight about the isotope build-up of the installation which allowed estimating the time of reaching the stationary regime. Also transient regimes following perturbations in the operating parameters (i.e. temperature, pressure, fluid rates) of the installation were simulated and an optimal rate of routine inspections and adjustments was thus established