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Sample records for non-participants eleven studies

  1. Deep Energy Retrofits - Eleven California Case Studies

    Energy Technology Data Exchange (ETDEWEB)

    Less, Brennan [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Fisher, Jeremy [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Walker, Iain [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2012-10-01

    This research documents and demonstrates viable approaches using existing materials, tools and technologies in owner-conducted deep energy retrofits (DERs). These retrofits are meant to reduce energy use by 70% or more, and include extensive upgrades to the building enclosure, heating, cooling and hot water equipment, and often incorporate appliance and lighting upgrades as well as the addition of renewable energy. In this report, 11 Northern California (IECC climate zone 3) DER case studies are described and analyzed in detail, including building diagnostic tests and end-use energy monitoring results. All projects recognized the need to improve the home and its systems approximately to current building code-levels, and then pursued deeper energy reductions through either enhanced technology/ building enclosure measures, or through occupant conservation efforts, both of which achieved impressive energy performance and reductions. The beyond-code incremental DER costs averaged $25,910 for the six homes where cost data were available. DERs were affordable when these incremental costs were financed as part of a remodel, averaging a $30 per month increase in the net-cost of home ownership.

  2. Self-assessed health, perceived stress and non-participation in breast cancer screening: A Danish cohort study

    DEFF Research Database (Denmark)

    Jensen, Line Flytkjær; Pedersen, Anette Fischer; Andersen, Berit

    2015-01-01

    Objective Population-based cancer screening is offered in many countries to detect early stages of cancer and reduce mortality. Screening efficiency and equality is susceptible due to a group of non-participants. We investigated associations between self-assessed health, perceived stress...... and subsequent non-participation in breast cancer screening. Methods This population-based cohort study included 4512 women who had participated in a Health Survey in 2006 and who were also the target group (aged 50–69 years) for the first organised breast cancer screening programme -3 years later in the Central...

  3. Reasons for non-participation in a parental program concerning underage drinking: a mixed-method study

    Directory of Open Access Journals (Sweden)

    Eriksson Charli

    2009-12-01

    Full Text Available Abstract Background Alcohol consumption among adolescents is a serious public health concern. Research has shown that prevention programs targeting parents can help prevent underage drinking. The problem is that parental participation in these kinds of interventions is generally low. Therefore, the aim of the present study is to examine non-participation in a parental support program aiming to prevent underage alcohol drinking. The Health Belief Model has been used as a tool for the analysis. Methods To understand non-participation in a parental program a quasi-experimental mixed-method design was used. The participants in the study were invited to participate in a parental program targeting parents with children in school years 7-9. A questionnaire was sent home to the parents before the program started. Two follow-up surveys were also carried out. The inclusion criteria for the study were that the parents had answered the questionnaire in school year 7 and either of the questionnaires in the two subsequent school years (n = 455. Multinomial logistic regression analysis was used to examine reasons for non-participation. The final follow-up questionnaire included an opened-ended question about reasons for non-participation. A qualitative content analysis was carried out and the two largest categories were included in the third model of the multinomial logistic regression analysis. Results Educational level was the most important socio-demographic factor for predicting non-participation. Parents with a lower level of education were less likely to participate than those who were more educated. Factors associated with adolescents and alcohol did not seem to be of significant importance. Instead, program-related factors predicted non-participation, e.g. parents who did not perceive any need for the intervention and who did not attend the information meeting were more likely to be non-participants. Practical issues, like time demands, also seemed to

  4. A study of weeding policies in eleven TALON resource libraries.

    Science.gov (United States)

    Goldstein, C H

    1981-01-01

    A study was made of the weeding policies and practices of eleven TALON resource libraries. The results indicated that although weeding, or collection evaluation as it is also known, was performed by most of the libraries, few had a written policy. The reasons for weeding and the types of weeding done by the libraries are described. A discussion of the prevalent means of disposition of withdrawn materials and of the obstacles to cooperative weeding is included. PMID:7248594

  5. A study of weeding policies in eleven TALON resource libraries.

    Science.gov (United States)

    Goldstein, C H

    1981-07-01

    A study was made of the weeding policies and practices of eleven TALON resource libraries. The results indicated that although weeding, or collection evaluation as it is also known, was performed by most of the libraries, few had a written policy. The reasons for weeding and the types of weeding done by the libraries are described. A discussion of the prevalent means of disposition of withdrawn materials and of the obstacles to cooperative weeding is included.

  6. A study of weeding policies in eleven TALON resource libraries.

    OpenAIRE

    Goldstein, C H

    1981-01-01

    A study was made of the weeding policies and practices of eleven TALON resource libraries. The results indicated that although weeding, or collection evaluation as it is also known, was performed by most of the libraries, few had a written policy. The reasons for weeding and the types of weeding done by the libraries are described. A discussion of the prevalent means of disposition of withdrawn materials and of the obstacles to cooperative weeding is included.

  7. Allergy in bakers' apprentices and factors associated to non-participation in a cohort study of allergic sensitization

    DEFF Research Database (Denmark)

    Skjold, Tina; Nielsen, Sven C; Adolf, Katja;

    2006-01-01

    Objective  To describe the prevalence of atopy and respiratory symptoms among baker apprentices at the start of the education and factors associated with non-participation in the study. Methods  A total of 346 students, 22.1(0.6) years of age, mean (SD), from the food production programme...... of technical colleges in Denmark were invited to participate in a 3 year study. Of the students, 187 agreed to participate and filled in a physician-administered questionnaire. The presence of atopy was determined by skin prick test (SPT) and serum allergen specific IgE (SpIgE). Bronchial hyper responsiveness...

  8. Controversies about cervical cancer screening: A qualitative study of Roma women's (non)participation in cervical cancer screening in Romania.

    Science.gov (United States)

    Andreassen, Trude; Weiderpass, Elisabete; Nicula, Florian; Suteu, Ofelia; Itu, Andreea; Bumbu, Minodora; Tincu, Aida; Ursin, Giske; Moen, Kåre

    2017-06-01

    Romania has Europe's highest incidence and mortality of cervical cancer. While a free national cervical cancer-screening programme has been in operation since 2012, participation in the programme is low, particularly in minority populations. The aim of this study was to explore Roma women's (non)participation in the programme from women's own perspectives and those of healthcare providers and policy makers. We carried out fieldwork for a period of 125 days in 2015/16 involving 144 study participants in Cluj and Bucharest counties. Fieldwork entailed participant observation, qualitative interviewing and focus group discussions. A striking finding was that screening providers and Roma women had highly different takes on the national screening programme. We identified four fundamental questions about which there was considerable disagreement between them: whether a free national screening programme existed in the first place, whether Roma women were meant to be included in the programme if it did, whether Roma women wanted to take part in screening, and to what degree screening participation would really benefit women's health. On the background of insights from actor-network theory, the article discusses to what degree the programme could be said to speak to the interest of its intended Roma public, and considers the controversies in light of the literature on patient centred care and user involvement in health care. The paper contributes to the understanding of the health and health-related circumstances of the largest minority in Europe. It also problematizes the use of the concept of "barriers" in research into participation in cancer screening, and exemplifies how user involvement can potentially help transform and improve screening programmes. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  9. Non-participation in breast cancer screening for persons with chronic diseases and multimorbidity: a population-based cohort study

    DEFF Research Database (Denmark)

    Andersen, Berit

    2015-01-01

    –96 %). Higher non-participation was also observed for women with severe multimorbidity (PR = 1.53, 95 % CI: 1.23–1.90) and mental-physical multimorbidity (PR = 1.54, 95 % CI: 1.36–1.75). Conclusion In conclusion, we found a strong association between non-participation in breast cancer screening for some chronic......-participation was found for women with cancer (PR = 1.50, 95 % CI: 1.40–1.60), mental illness (PR = 1.51, 95 % CI: 1.42–1.60), chronic obstructive pulmonary disease (PR = 1.51, 95 % CI: 1.42–1.62), neurological disorders (PR = 1.24, 95 % CI: 1.12–1.37) and kidney disease (PR = 1.70, 95 % CI 1.49–1.94), whereas women...

  10. Representativeness of Participants in a Lifestyle Intervention Study in Obese Pregnant Women - the Difference between Study Participants and Non-Participants

    Directory of Open Access Journals (Sweden)

    Joanna Gesche

    2014-11-01

    Full Text Available Objective: To examine the representativeness of participants attending a lifestyle intervention study addressing obese pregnant women. Methods: Retrospective comparison of baseline data, attendance to oral glucose tolerance test (OGTT during pregnancy, and pregnancy outcome in eligible women stratified according to study participation. Of 750 eligible women with a self-reported BMI > 30 kg/m2, and a live singleton pregnancy, 510 were eligible for inclusion and 425 were randomized to either active intervention (n= 284 or to standard obstetric care (n= 141 including two standard OGTT. The 85 women who declined participation or were excluded due to competing diseases and 240 women who did not respond to the initial invitation received the same standard care. Results: The randomized women had similar BMI but a lower parity and age, and were more frequently non-smokers, born in Denmark and married or cohabitating with their partner than the non-participants. Women participating in the trial had a higher compliance to the second OGTT compared to non-participants, also after correcting for age and nationality. There was no difference in pregnancy outcome, i.e., fetal weight and length, gestational age as well as mode of delivery. Conclusion: Women declining participation in a randomized lifestyle intervention study in pregnancy have characteristics indicating they are those who might benefit the most from lifestyle intervention.

  11. Comparison of participants and non-participants in a randomized study of prevention of depression in patients with acute coronary syndrome

    DEFF Research Database (Denmark)

    Hansen, Baiba; Hanash, Jamal A.; Rasmussen, Alice;

    2011-01-01

    Background: The prevalence of depression and anxiety in patients after acute coronary syndrome (ACS) is higher than in the general population. In a study on prevention of post-ACS depression, more than half of eligible patients declined participation. Aims: The aim of this study was to evaluate...... but did not predict participation in the study of prevention of depression....... whether symptoms of depression and anxiety in participants and non-participants predicted participation in the study. Methods: This substudy was conducted between May 2005 and April 2007. Patients with ACS, eligible for the study (n=302) were asked four questions on depression and anxiety from the Primary...

  12. Non-participation in population-based disease prevention programs in general practice

    Directory of Open Access Journals (Sweden)

    Koopmans Berber

    2012-10-01

    Full Text Available Abstract Background The number of people with a chronic disease will strongly increase in the next decades. Therefore, prevention of disease becomes increasingly important. The aim of this systematic review was to identify factors that negatively influence participation in population-based disease prevention programs in General Practice and to establish whether the program type is related to non-participation levels. Methods We conducted a systematic review in Pubmed, EMBASE, CINAHL and PsycINFO, covering 2000 through July 6th 2012, to identify publications including information about characteristics of non-participants or reasons for non-participation in population-based disease prevention programs in General Practice. Results A total of 24 original studies met our criteria, seven of which focused on vaccination, eleven on screening aimed at early detection of disease, and six on screening aimed at identifying high risk of a disease, targeting a variety of diseases and conditions. Lack of personal relevance of the program, younger age, higher social deprivation and former non-participation were related to actual non-participation. No differences were found in non-participation levels or factors related to non-participation between the three program types. The large variation in non-participation levels within the program types may be partly due to differences in recruitment strategies, with more active, personalized strategies resulting in higher participation levels compared to an invitation letter. Conclusions There is still much to be gained by tailoring strategies to improve participation in those who are less likely to do so, namely younger individuals, those living in a deprived area and former non-participants. Participation may increase by applying more active recruitment strategies.

  13. The population-based oncological health care study OVIS – recruitment of the patients and analysis of the non-participants

    Directory of Open Access Journals (Sweden)

    Raspe Heiner

    2008-10-01

    Full Text Available Abstract Background The ageing of the population is expected to bring an enormous growth in demand for oncological health care. In order to anticipate and respond to future trends, cancer care needs to be critically evaluated. The present study explores the possibility of conducting representative and population-based research on cancer care on the basis of data drawn from the Cancer Registry. Methods A population-based state-wide cohort study (OVIS has been carried out in Schleswig-Holstein, Germany. All patients with malignant melanoma, breast, or prostate cancer were identified in the Cancer Registry. Epidemiological data were obtained for all the patients and screened for study eligibility. A postal questionnaire requesting information on diagnosis, therapy, QoL and aftercare was sent to eligible patients. Results A total of 11,489 persons diagnosed with the cancer types of interest in the period from January 2002 to July 2004 were registered in the Cancer Registry. Of the 5,354 (47% patients who gave consent for research, 4,285 (80% of consenters completed the questionnaire. In terms of relevant epidemiological variables, participants with melanoma were not found to be different from non-participants with the same diagnosis. However, participants with breast or prostate cancer were slightly younger and had smaller tumours than patients who did not participate in our study. Conclusion Population-based cancer registry data proved to be an invaluable resource for both patient recruitment and non-participant analysis. It can help improve our understanding of the strength and nature of differences between participants and non-respondents. Despite minor differences observed in breast and prostate cancer, the OVIS-sample seems to represent the source population adequately.

  14. Comparison of participants and non-participants in a randomized study of prevention of depression in patients with acute coronary syndrome

    DEFF Research Database (Denmark)

    Hansen, Baiba; Hanash, Jamal A.; Rasmussen, Alice;

    2011-01-01

    Care Evaluation of Mental Disorders (PRIME-MD) screening questionnaire. Results: The PRIME-MD screening data were available on 232 patients (76.8% of eligible patients). Thirty-eight (35.5%) of 107 participants and 30 (24.0%) of 125 non-participants had a positive screening for depression (NS), and 47...... (43.9%) participants and 55 (44%) non-participants were screened positive for anxiety (NS). Non-participants were older (P=0.002), while no significant differences in gender or cardiac diagnosis were found. Conclusions: Symptoms of depression and anxiety were highly prevalent in patients after ACS...

  15. [Leaf anatomy study in Solanaceae of Venezuela. V. leaf anatomy of eleven species of Cestrum L] .

    Science.gov (United States)

    Jáuregul, D; Rodriguez, N; Benítez, C E

    2000-01-01

    Leaf anatomy of the following eleven species: C. buxifolium Kunth, C. humboldtii Francey, C. lindenii Dunal, C. mariquitense Kunth, C. megalophyllum Dunal, C. olivaceum Francey, C. pariense Steyerm., C petiolare Kunth, C. scandans Vahl, C. strigilatum Ruiz et Pavón and C. tomentosum L.f. is described. Transverse sectioning, bruise and clearing according to the classical methods for optical microscopy were made. The species studied show dissimilitude in relation to a) fohar blade: thickness and sinuosity of epidermal cell walls; type, density and presence of trichornes, leaf type according the position of the stomata, thickness of both palisade and spongy parenchy-ma, number of spongy parenchyma layers, occurrence or not of paranchymatous sheath and sclerifled cells in mesophyll, tmbeculae or projection walls b) Midvein: degree of development and arrangement of the parenchyma and collenchyma, c) Petiole: size and form in transverse section, presence of ornamented cuticle, peridermis and degree of development of the sclerenctiyma next to vascular bundles.

  16. Coffee consumption and risk of hepatocellular carcinoma: a meta-analysis of eleven epidemiological studies

    Directory of Open Access Journals (Sweden)

    Bai K

    2016-07-01

    Full Text Available Kai Bai,* Qiucheng Cai,* Yi Jiang, Lizhi Lv Department of Hepatobiliary Surgery, Fuzong Clinical College, Fujian Medical University, Fuzhou, People’s Republic of China *These authors contributed equally to this work Abstract: Growing evidence has shown that coffee consumption is inversely related with the risk of hepatocellular carcinoma. It is suggested that caffeine maintains strong antioxidative activity. With this property, coffee intake may lead to the inhibition of cell proliferation of liver cancer cells; also, some compounds contained in coffee can reduce the genotoxicity of aflatoxin B1 in vitro and lower the damage caused by some carcinogens. A computerized search was performed in PubMed to identify relevant articles published before August 2015. Eleven relevant studies were included with a total of 2,795 cases and 340,749 control subjects. According to the meta-analysis we performed, the pooled odds ratio (OR from all included studies was 0.49 (95% confidence interval [CI] =0.46–0.52. The subgroup analysis indicated that the pooled ORs for Asian studies and other populations were 0.27 (95% CI =0.23–0.31 and 0.82 (95% CI =0.77–0.87, respectively. The overall pooled OR for high consumption was decreased to 0.21 (95% CI =0.18–0.25 and significance was observed. Among other populations, the pooled OR of subjects with high coffee consumption was 0.65 (95% CI =0.56–0.73 compared to the nondrinker. The corresponding OR of five Asian studies was 0.13 (95% CI =0.09–0.17. The findings from this meta-analysis further confirmed the inverse association between the coffee consumption and hepatocellular carcinoma risk with quantitative evidence. The protective effect can be detected among healthy population and patients with chronic liver diseases, and the consumption can also prevent the development of liver cirrhosis. Keywords: hepatocarcinogenesis, meta-analysis, coffee, antioxidant

  17. Representativeness of participants in a lifestyle intervention study in obese pregnant women - the difference between study participants and non-participants

    DEFF Research Database (Denmark)

    Gesche, Joanna; Renault, Kristina; Nørgaard, Kirsten

    2014-01-01

    OBJECTIVE: To examine the representativeness of participants attending a lifestyle intervention study addressing obese pregnant women. METHODS: Retrospective comparison of baseline data, attendance to oral glucose tolerance test (OGTT) during pregnancy, and pregnancy outcome in eligible women......, gestational age as well as mode of delivery. CONCLUSION: Women declining participation in a randomized lifestyle intervention study in pregnancy have characteristics indicating they are those who might benefit the most from lifestyle intervention....... stratified according to study participation. Of 750 eligible women with a self-reported BMI > 30 kg/m(2), and a live singleton pregnancy, 510 were eligible for inclusion and 425 were randomized to either active intervention (n= 284) or to standard obstetric care (n= 141) including two standard OGTT. The 85...

  18. Predictors of non-participation in cervical screening in Denmark

    DEFF Research Database (Denmark)

    Kristensson, Jenny Hansen; Sander, Bente Braad; von Euler-Chelpin, My

    2014-01-01

    PURPOSE: The aims of this study were to identify demographic and socio-economic predictors of non-participation in cervical screening in Denmark, and to evaluate the influence of health care use on screening participation. METHODS: A population based register study was undertaken using data from ...

  19. Mortality of non-participants in cervical screening

    DEFF Research Database (Denmark)

    Dugué, Pierre-Antoine; Lynge, Elsebeth; Rebolj, Matejka

    2014-01-01

    a HR of 2.09 (95% CI: 2.05-2.14) compared to regular participants. The HR for human papillomavirus (HPV)-related cancers other than cervical cancer was 3.80 (95% CI: 2.67-5.41). Younger women, whose coverage rates were higher, had higher all-cause mortality HRs. Women screened more frequently than......The selective uptake of screening by healthy participants and its impact on the evaluation of screening effectiveness in non-randomized studies have been discussed, but hardly studied. We quantified excess mortality among cervical screening non-participants compared to participants. Based on Danish...... healthcare registers, we determined women's participation in cervical screening in 1990-1993 (one screening round) and 1990-1997 (two screening rounds). Women were followed until end of 2010. We computed hazard ratios (HR) comparing non-participants' and participants' risk of death, and analyzed the impact...

  20. [Follow-up study of eleven autistic children originally reported in 1943. 1971].

    Science.gov (United States)

    Kanner, L

    1995-01-01

    The destinies of the 11 children first reported in 1943 as suffering from autistic disturbances of affective contact are brought up to date. Their life histories are summarized succinctly in terms of developmental data, family constellations, clinical observations in the course of the years, the varieties of professional planning, and present status. Attention is called to the subsequent scientific studies of early infantile autism with ever-increasing facilities for research in nosology, biochemical and general systemic implication, and therapeutic amelioration. The need for continued follow-up studies of autistic children is emphasized.

  1. The impact of extremely low frequency electromagnetic fields on stream periphyton: An eleven-year study

    Science.gov (United States)

    Burton, T.M.; Uzarski, D.G.; Stelzer, R.S.; Eggert, S.L.; Sobczak, W.V.; Mullen, D.M.

    2000-01-01

    Potential effects of extremely low frequency (ELF) electromagnetic fields on periphyton were studied from 1983 to 1993 using a Before, After, Control and Impact design. The study was conducted at two sites on the Ford River, a fourth-order brown water trout stream in Dickinson County, Michigan. The Reference site received 4.9-6.5 times less exposure to ground electric fields and from 300 to 334 times less exposure to magnetic flux from 1989 to 1993 when the antenna was operational at 76 Hz than did the Antenna site. The objective of the study was to determine if ELF electromagnetic fields had caused changes in structure and/or function of algal communities in the Ford River. Significant differences in chlorophyll a standing crop and daily accumulation rate (a surrogate for primary productivity), and organic matter standing crop and daily accumulation rate were observed between the Reference and Antenna site after the antenna became operational. These four related community function variables all increased at the Antenna site with largest and most consistent increases occurring for chlorophyll measures. Compared to pre-operational data, the increase in chlorophyll at the Antenna site also occurred during a period of low amperage testing in 1986-1988, and did not increase further when the antenna became fully operational in 1989, indicating a low threshold for response. There was no significant differences between the Antenna and Reference sites in community structure variables such as diversity, evenness and the relative abundance of dominant diatoms. Thus, 76 Hz ELF electromagnetic radiation apparently did not change the basic makeup of the diatom community but did increase accumulation rates and standing crops of chlorophyll a and organic matter.

  2. Eleven-Year Retrospective Survival Study of 275 Veneered Lithium Disilicate Single Crowns.

    Science.gov (United States)

    Simeone, Piero; Gracis, Stefano

    2015-01-01

    The aim of the present clinical retrospective study was to evaluate the long-term survival and clinical performance of veneered lithium disilicate single restorations in anterior and posterior areas after up to 11 years. Following a rigid protocol, 275 lithium disilicate single crowns (35 IPS Empress II and 240 e.max Press) were cemented over 11 years, in 106 patients, using an adhesive technique; of these 106 were anterior (38.5%) and 169 posterior (61.5%) teeth. Teeth receiving endodontic therapy and composite reconstruction (50%) and teeth with preexisting metalceramic crowns, called prosthetic retreatments (PR; 65%), were included as well. Of the 106 patients enrolled in the study, 25 (23.5%) were diagnosed with bruxism habits, and 7 of these patients (6.6% of all patients) received full-mouth single lithium disilicate restorations (FMR). The exclusion criteria for this retrospective clinical study were: monolithic lithium disilicate crowns, teeth with cast post and cores, implant-supported all-ceramic crowns, active periodontitis, and/or poor oral hygiene. Clinical reevaluation was performed by the clinicians who prepared and luted them during maintenance appointments between January 2012 and October 2013. Number of restoration failures and characteristics of failures were recorded. Marginal adaptation and marginal discoloration were evaluated based on the Cvar-Ryge criteria. The overall cumulative survival rate was 98.2%. The failures recorded were the result of either mechanical failure or debonding. Five crowns failed mechanically-three because of chipping and two because of core fracture-and were replaced. None of the failed crowns was associated with the bruxers with FMR. A total of 15 crowns debonded (5.5% of all crowns); however, 11 belonged to the same patient who had endodontically treated and reconstructed abutments. In this retrospective clinical evaluation of up to 132 months, veneered lithium disilicate single crowns had a low failure rate.

  3. A Retrospective Study of the Epidemiology of Leprosy in Cebu: An Eleven-Year Profile

    Science.gov (United States)

    Scheelbeek, Pauline F. D.; Balagon, Marivic V. F.; Orcullo, Florenda M.; Maghanoy, Armi A.; Abellana, Junie; Saunderson, Paul R.

    2013-01-01

    Background Cebu has been one of the most leprosy endemic areas in the Philippines. Despite the high coverage rates of multiple drug therapy (MDT) and high BCG-vaccine coverage in children, leprosy control authorities believe that leprosy transmission and incidence (as evidence by continuing new case detection in both adults and children) have not declined as expected, once leprosy had been eliminated. In response to the concerns communicated by the authorities regarding ongoing leprosy transmission in Cebu, this study aims to examine the evidence for the hypothesized ongoing transmission, both in children and adults. Furthermore, it will be assessed which groups and areas are experiencing a continuing risk of leprosy infection; this can form a starting point for more targeted approaches to leprosy control. Methodology & Principal Findings Case records from 2000–2010 were retrospectively collected from the Leonard Wood Memorial Clinic archives, and all other clinics on the island where leprosy was treated. Between 2000 and 2010, 3288 leprosy cases were detected. The overall five year case notification rate (CNR) dropped significantly from 47.35 (2001–2005) to 29.21 cases (2006–2010) per 100.000 population. Smaller CNRs were reported for children; however the decline in child-CNR over the same period was minimal. Furthermore, no increase in median age of notification in children or adults was found between 2000 and 2010. Population-adjusted clustering of leprosy cases was mainly detected in urban and peri-urban areas. Conclusions & Significance Although the overall CNR declined significantly, CNR seems to be rather static in lower risk populations and areas. Cases are mainly found in urban areas, however CNRs in these areas decline at a much faster rate than in the lower endemic rural areas. A similar situation was found when comparing adults and children: CNRs observed in children were lower than in adults, but further decline (and elimination) of these

  4. Non-participants and reasons for non-participation in a pragmatic trial of energy healing as cancer rehabilitation

    DEFF Research Database (Denmark)

    Techau, Marzcia Elisa Camille; Lunde, Anita; Pedersen, Christina Gundgaard;

    2014-01-01

    -participation in a pragmatic trial of energy healing for rehabilitation for colorectal cancer. Methods: Three to seven days after postal recruitment, all eligible participants (n=783) were contacted by telephone. Reasons given for non-participation were recorded in 5 categories. Data were analyzed using Chi2. Results: More...

  5. 7-Eleven Melejit Lewat Lifestyle

    Directory of Open Access Journals (Sweden)

    Freddy Pandapotan Simbolon

    2012-04-01

    uncautioned wholly by the customers when doing shopping. Since officially opened, the 7-Eleven had offered unique facilities. Instead of providing instant foods and beverages for 24 hours, the 7-Eleven also provides convenient corners and tables to eat and drink and provides chatting facilities for customers who need it. These make other modern retailers following the concept: opened for 24 hours and providing chatting facilities for young people.

  6. Teacher's Supplement to Unit on U.S.S.R. Grade Eleven. [Unit II.] Project Social Studies.

    Science.gov (United States)

    Minnesota Univ., Minneapolis. Project Social Studies Curriculum Center.

    This is a subunit to one of four resource units for an eleventh grade course on area studies. This subunit is a teacher's supplement to the unit on the U.S.S.R. A pretest on the Soviet Union, supplementary readings on the Soviet economy, foreign policy, constitution, government, Soviet attitudes toward the United States, and comparative statistics…

  7. The Prevalence of Idiopathic Scoliosis in Eleven Year-Old Korean Adolescents: A 3 Year Epidemiological Study

    OpenAIRE

    Lee, Jin-Young; Moon, Seong-Hwan; Kim, Han Jo; Park, Moon Soo; Suh, Bo-Kyung; Nam, Ji Hoon; Jung, Jae Kyun; Lee, Hwan-Mo

    2014-01-01

    Purpose School screening allows for early detection and early treatment of scoliosis, with the purpose of reducing the number of patients requiring surgical treatment. Children between 10 and 14 years old are considered as good candidates for school screening tests of scoliosis. The purpose of the present study was to assess the epidemiological findings of idiopathic scoliosis in 11-year-old Korean adolescents. Materials and Methods A total of 37856 11-year-old adolescents were screened for s...

  8. Summary of an eleven-country study of socio-legal measures to combat drug abuse and related crime.

    Science.gov (United States)

    Asuni, T; Bruno, F

    1984-01-01

    In a comparative study of a group of experimental and control subjects in Argentina, Brazil, Costa Rica, Japan, Jordan, Italy, Malaysia, Singapore and the United States of America (State of New York), and of the results of independent studies conducted in Sweden and the United Kingdom of Great Britain and Northern Ireland, a rather close association was found to exist between drug abuse, criminal behaviour and social attitudes to such problems. Both drug abuse and the socio-legal systems varied greatly in the countries involved. No correlation was found between the level of foreseen or actual harshness of the socio-legal system and the level of seriousness of drug abuse and its associated criminality, but there was a significant correlation between knowledge of the law and the efficacy of the socio-legal system. In each country informal control systems, such as the family, church, school, neighbourhood and work environment, were active. Approximately one half of the subjects that were interviewed from countries with the most punitive socio-legal systems perceived informal controls as harsh and punitive while in the other countries such controls were generally perceived as positive. The study encouraged the review, testing and implementation of alternative measures to penal sanctions, particularly with a view to creating a genuine therapeutic approach to correcting the deviant behaviour of drug abusers.

  9. Quantitation of eleven active compounds of Aidi injection in rat plasma and its application to comparative pharmacokinetic study.

    Science.gov (United States)

    Liu, Ran; Ma, Ran; Yu, Chunyu; Bi, Cathy Wenchuan; Yin, Yidi; Xu, Huarong; Shang, Hongwei; Bi, Kaishun; Li, Qing

    2016-07-15

    Aidi injection has been widely used for the treatment of colorectal cancer. The purpose of this study was to develop a sensitive and reliable method for simultaneous quantitation of 11 main active ingredients in Aidi injection and to compare the pharmacokinetics of these ingredients in normal and colorectal model cancer rats after tail vein injection. After being extracted by isopropanol-ethyl acetate (1:1, v/v), the plasma samples were analyzed with domperidone as internal standard. Then the analytes were separated on a Venusil MP C18 column with 0.15% formic acid and methanol. The detection was performed on HPLC-MS/MS system with turbo ion spray source in the positive ion and multiple reaction-monitoring mode. The assay was shown to be linear over the range of 0.004-4.0μgmL(-1) of syringin B, astragaloside II and isofraxidin; 0.01-10.0μgmL(-1) of calycosin-7-O-β-d-glucoside and astragaloside IV; 0.02-20.0μgmL(-1) of ginsenoside Rg1, Rb1, Rc and Rd; 0.04-40.0μgmL(-1) of syringin E; 0.06-60.0μgmL(-1) of ginsenoside Re. And the validated method has been successfully applied to compare pharmacokinetic profiles of the 11 ingredients in plasma. The pharmacokinetic results showed here were significant differences in pharmacokinetic parameters for eight analytes between two groups after injection, while no significant differences for astragaloside II, astragaloside IV and ginsenoside Rc. The present study has the advantages of short analysis time and easy sample preparation, which could more comprehensively reflect the quality of Aidi injection in single run. The method proposed could be of great use for pharmacokinetics, bioavailability or bioequivalence studies of Aidi injection in biological samples.

  10. Factors Influencing Usage of an Electronic Journal Collection at a Medium-Size University: An Eleven-Year Study.

    Directory of Open Access Journals (Sweden)

    Alain R. Lamothe

    2012-05-01

    Full Text Available This paper reports the results of a quantitative analysis examining factors affecting electronic journal usage at the J.N. Desmarais Library of Laurentian University. This study covered an 11-year period, from 2000 to 2010. The number of full-text articles downloaded was compared to the size of the e-journal collection, the number of students, and the number of faculty members at the university, all of which exerted varying degrees of influence on the rate of use of e-journals. Pearson’s Product-Moment Correlation Coefficients were calculated to determine the strength of any existing linear relationship. Although the size of the e-journal collection did impact its level of use, there seems to be a “critical mass” which once reached will slow or stop any further increase in usage. Among the student population, the number of doctoral students demonstrated the strongest linear relationship to the use of the e-journal collection while the undergraduate population showed the least strong linear relationship. Faculty members were important users of the library’s e-journal collection but the linear relationship was not as strong as that observed for graduate students. In fact, faculty members demonstrated the least strong linear relationship of all segments of the Laurentian University community. It may be wise for the library to consult not only its faculty members but also its graduate students when seeking advice on collection building and management.

  11. The Prevalence of Idiopathic Scoliosis in Eleven Year-Old Korean Adolescents: A 3 Year Epidemiological Study

    Science.gov (United States)

    Lee, Jin-Young; Moon, Seong-Hwan; Kim, Han Jo; Suh, Bo-Kyung; Nam, Ji Hoon; Jung, Jae Kyun; Lee, Hwan-Mo

    2014-01-01

    Purpose School screening allows for early detection and early treatment of scoliosis, with the purpose of reducing the number of patients requiring surgical treatment. Children between 10 and 14 years old are considered as good candidates for school screening tests of scoliosis. The purpose of the present study was to assess the epidemiological findings of idiopathic scoliosis in 11-year-old Korean adolescents. Materials and Methods A total of 37856 11-year-old adolescents were screened for scoliosis. There were 17110 girls and 20746 boys. Adolescents who were abnormal by Moiré topography were subsequently assessed by standardized clinical and radiological examinations. A scoliotic curve was defined as 10° or more. Results The prevalence of scoliosis was 0.19% and most of the curves were small (10° to 19°). The ratio of boys to girls was 1:5.5 overall. Sixty adolescents (84.5%) exhibited single curvature. Thoracolumbar curves were the most common type of curve identified, followed by thoracic and lumbar curves. Conclusion The prevalence of idiopathic scoliosis among 11-year-old Korean adolescents was 0.19%. PMID:24719147

  12. Using participant or non-participant observation to explain information behaviour. Participant observation, Non-participant observation, Information behaviour, Hospital pharmacists, Older people

    Directory of Open Access Journals (Sweden)

    Janet Cooper

    2004-01-01

    Full Text Available The aim of the paper is to provide guidance on conducting participant and non-participant observation studies of information behaviour. Examines lessons learned during non-participant observation of hospital pharmacists, and participant observation with dependent older people living in their own homes. Describes the methods used in both studies, and discusses the ethical issues involved in gaining access to the subjects. In the hospital setting, professional affiliation between the researcher and the subjects (six pharmacists made access easier to obtain. In the home care setting, access to subjects (seven clients for participant observation (as a care worker was more difficult, as was withdrawal from the field study. In both studies, the observation element was triangulated with survey data. Both studies indicated the fundamental need for trust between the observer and the research subjects. In some situations, professional relations offer instant access and trust, whereas in closed and sensitive situations such as social care, time is required to build up trust. With participant observation, that trust should not be damaged by withdrawal of the researcher from the research setting.

  13. Non-participation in preventive child health examinations at the general practitioner in Denmark

    DEFF Research Database (Denmark)

    Søndergaard, Grethe; Biering-Sørensen, Sofie; Michelsen, Susan Ishøy

    2008-01-01

    , and older siblings) and parental characteristics (age, educational level, attachment to labour market, ethnicity, household income, and number of adults in the household). Results. Children of young and single parents were less likely to receive a preventive child health examination. Increased odds ratios......Objective. To examine demographic and socioeconomic characteristics of parents and children in families not participating in preventive child health examinations at the general practitioner in a society with free and easy access to healthcare. Design. Population-covering register linkage study...... for non-participation were found for children of parents outside the labour market, with low educational level, and especially for the combination of these. Non-participation increased with decreasing household income and with the number of older siblings. Conclusion. Despite the fact that Denmark has...

  14. 7-Eleven Melejit Lewat Lifestyle

    Directory of Open Access Journals (Sweden)

    Freddy P. Simbolon

    2012-05-01

    Full Text Available The landscape of convenient store businesses or minimarkets now have changed. Location base strategy has not been sufficient any longer now. Psychographic and Demographic approaches tend to share a newly built power. Two main variables that have been managed concern at retail level are the store image and the store atmosphere. While the store image dimensions that can be put into considerations are the items offered, services committed, who and the amount of customers, physical facilities, promotion and convenience, store atmosphere, especially the involvement of affections through built emotions status in store which possibly uncautioned wholly by the customers when doing shopping. Since officially opened, the 7-Eleven had offered unique facilities. Instead of providing instant foods and beverages for 24 hours, the 7-Eleven also provides convenient corners and tables to eat and drink and provides chatting facilities for customers who need it. These make other modern retailers following the concept: opened for 24 hours and providing chatting facilities for young people.

  15. Neurocisticercosis en un hospital de la ciudad de Buenos Aires: estudio de once casos Neurocysticercosis in Buenos Aires: a study of eleven patients in a metropolitan hospital

    Directory of Open Access Journals (Sweden)

    A. M. Villa

    1993-09-01

    Full Text Available Fueron examinados 11 pacientes adultos con el diagnostico presuntivo de neuro-cisticercosis, 8 de ellos provenientes de Bolivia y los restantes del interior de la Argentina. Como manifestacion clinica inicial el 82% de ellos mostro convulsiones y el 73% cefaleas. Ambas alteraciones podían estar combinadas en el mismo paciente o presentarse en forma independiente. La tomografia computada de cerebro evidencio calcificaciones y quistes en 5 enfermos, solo calcificaciones en 3, hidrocefalia en 2 y un unico quiste en 1. En 7 casos se efectuo ELISA en el LCR, de ellos 6 resultaron positivos. El tratamiento medico se hizo en base a la administración de praziquantel o albendazol con buena evolución de los pacientes en todos los casos. El tratamiento quirúrgico fue indicado solo en el caso en que una lesion actuase como masa ocupante con aumento de la presión endocraneana (1 caso o produjera obstruccion de la circulacon del LCR llevando a una hidrocefalia (2 casos. El estudio presente pretende alertar sobre la posibilidad que nuevas regiones, como la Ciudad de Buenos Aires, puedan ingresar dentro del area endemica latinoamericana a consecuencia de los movimientos migratorios internos y externos y el asentamiento de portadores de la parasitosis en el perimetro urbano.Eleven patients with diagnosis of possible neurocistycercosis were studied in our Department since 1986. All of them were adults. Eight were Bolivian citizens. The commonest neurological clinical manifestation were seizures and/or headache. Brain CT scans showed cystic lesions and calcifications in 5 patients, only calcifications in 3, enlarged ventricles in 2 and an isolated frontal cystic lesion in 1. Six out of 7 patients who were submitted to spinal fluid ELISA test showed positive response for cysticercosis. Patients were put on praziquantel (50mg/Kg/d or albendazol (15mg/Kg/d with good outcome for all them. Surgery was carried on for treatment of enlarged ventricles (2 patients and

  16. Differences between participants and non-participants in an RCT on physical activity and psychological interventions for older persons

    NARCIS (Netherlands)

    van Heuvelen, MJG; Hochstenbach, JBM; Brouwer, WH; de Greef, MHG; Zijlstra, GAR; van Jaarsveld, E; Kempen, GIJM; van Sonderen, E; Ormel, J; Mulder, T

    2005-01-01

    Background and aims: Volunteer bias in intervention studies on successful aging has been poorly explored. This paper investigated differences between participants and non-participants of the Groningen Intervention Study on Successful Aging (GISSA) over a wide range of demographic, physical, psycholo

  17. 5. Factors Associated with non-participation in a Research

    African Journals Online (AJOL)

    Esem

    the home based RCT VCT study in rural communities in .... and research scientists was reported over and over again as a barrier .... of intimate partner violence and divorce are important .... enrol their children in malaria clinical studies and the.

  18. No interest in landscape? The art of non-participation in Danish landscape planning

    DEFF Research Database (Denmark)

    Clausen, Laura Tolnov

    2017-01-01

    landscape planning, two key categories are identified as the deeper causes of people’s non-participation: the fear of the intimate, and the fear of the strange. A general conclusion is that non-participation can be explained in terms of ambivalence. The desire for landscape development does exist...

  19. Factors associated with non-participation and drop-out in a lifestyle intervention for workers with an elevated risk of cardiovascular disease.

    Science.gov (United States)

    Groeneveld, Iris F; Proper, Karin I; van der Beek, Allard J; Hildebrandt, Vincent H; van Mechelen, Willem

    2009-12-01

    Non-response and drop-out are problems that are commonly encountered in health promotion trials. Understanding the health-related characteristics of non-participants and drop-outs and the reasons for non-participation and drop-out may be beneficial for future intervention trials. Male construction workers with an elevated risk of cardiovascular disease (CVD) were invited to participate in a lifestyle intervention study. In order to investigate the associations between participation and CVD risk factors, and drop-out and CVD risk factors, crude and multiple logistic regression analyses were performed. The reasons for non-participation and drop-out were assessed qualitatively. 20% of the workers who were invited decided to participate; 8.6% of the participants dropped out before the first follow-up measurement. The main reasons for non-participation were 'no interest', 'current (para-)medical treatment', and 'feeling healthy', and for drop-out they were 'lack of motivation', 'current (para-)medical treatment', and 'disappointment'. Participants were 4.2 years older, had a higher blood pressure, higher total cholesterol, and lower HDL cholesterol than non-participants, and were more likely to report 'tiredness and/or stress' and 'chest pain and/or shortness of breath'. After adjusting for age, most risk factors were not significantly associated with participation. Drop-outs were 4.6 years younger than those who completed the study. The prevalence of smoking was higher among non-participants and drop-outs. Participants had a worse CVD risk profile than non-participants, mainly because of the difference in age. Non-participants and drop-outs were younger and more likely to be smokers. The main reasons for non-participation and drop-out were health-related. Investigators in the field of health promotion should be encouraged to share comparable information. Current Controlled Trials ISRCTN60545588.

  20. Social support and non-participation in breast cancer screening

    DEFF Research Database (Denmark)

    Jensen, Line Flytkjær; Pedersen, Anette Fischer; Andersen, Berit

    2015-01-01

    Social støtte har en positiv indflydelse på sundhedsadfærd, viser tidligere studier. Det er dog endnu ikke tilstrækkeligt belyst, om social støtte påvirker deltagelse i screening. I dette studie ses der nærmere på, om der er en sammenhæng mellem graden af social støtte (defineret som hyppigheden af...

  1. Non-participation during azithromycin mass treatment for trachoma in The Gambia: heterogeneity and risk factors.

    Directory of Open Access Journals (Sweden)

    Tansy Edwards

    2014-08-01

    Full Text Available There is concern that untreated individuals in mass drug administration (MDA programs for neglected tropical diseases can reduce the impact of elimination efforts by maintaining a source of transmission and re-infection.Treatment receipt was recorded against the community census during three MDAs with azithromycin for trachoma in The Gambia, a hypo-endemic setting. Predictors of non-participation were investigated in 1-9 year olds using random effects logistic regression of cross-sectional data for each MDA. Two types of non-participators were identified: present during MDA but not treated (PNT and eligible for treatment but absent during MDA (EBA. PNT and EBA children were compared to treated children separately. Multivariable models were developed using baseline data and validated using year one and two data, with a priori adjustment for previous treatment status. Analyses included approximately 10000 children at baseline and 5000 children subsequently. There was strong evidence of spatial heterogeneity, and persistent non-participation within households and individuals. By year two, non-participation increased significantly to 10.4% overall from 6.2% at baseline, with more, smaller geographical clusters of non-participating households. Multivariable models suggested household level predictors of non-participation (increased time to water and household head non-participation for both PNT and EBA; increased household size for PNT status only; non-inclusion in a previous trachoma examination survey and younger age for EBA only. Enhanced coverage efforts did not decrease non-participation. Few infected children were detected at year three and only one infected child was EBA previously. Infected children were in communities close to untreated endemic areas with higher rates of EBA non-participation during MDA.In hypo-endemic settings, with good coverage and no association between non-participation and infection, efforts to improve participation

  2. Fear of falling and self-perception of health in older participants and non-participants of physical activity programs

    Directory of Open Access Journals (Sweden)

    Carolina Kruleske da Silva

    2013-12-01

    Full Text Available Fear of falling, self-perception of health, and participation in physical activity programs have been associated with several variables related to health and performance in older adults. The purpose of this study was to evaluate self-perception of health and fear of falling in older adult participants and non-participants of physical activity programs, and to verify the relationship between these variables. A total of 40 healthy but sedentary older adults, and 45 physically active older adults were assessed through the Falls Efficacy Scale International-Brazil (FES-I and a questionnaire that measured their self-perception of health. The older adults that did not participate in regular physical activity programs presented higher scores of fear of falling, which, in turn, is associated with an increase of risk for falls. Moreover, older adults, participants in regular physical activity programs exhibited a more positive health perception than did the non-participants. Also, non-participants of physical activity programs perceived their health status as being poor or very poor as well as expressing great concern about falling compared to those who considered their health as excellent, good or regular. The results of this study have important implications for making clinical decisions in prevention or rehabilitation of older people, and they justify recommendations to the public health system.

  3. Cytotoxicity Potentials of Eleven Bangladeshi Medicinal Plants

    Directory of Open Access Journals (Sweden)

    Amina Khatun

    2014-01-01

    Full Text Available Various forms of cancer are rising all over the world, requiring newer therapy. The quest of anticancer drugs both from natural and synthetic sources is the demand of time. In this study, fourteen extracts of different parts of eleven Bangladeshi medicinal plants which have been traditionally used for the treatment of different types of carcinoma, tumor, leprosy, and diseases associated with cancer were evaluated for their cytotoxicity for the first time. Extraction was conceded using methanol. Phytochemical groups like reducing sugars, tannins, saponins, steroids, gums, flavonoids, and alkaloids were tested using standard chromogenic reagents. Plants were evaluated for cytotoxicity by brine shrimp lethality bioassay using Artemia salina comparing with standard anticancer drug vincristine sulphate. All the extracts showed potent to moderate cytotoxicity ranging from LC50 2 to 115 µg/mL. The highest toxicity was shown by Hygrophila spinosa seeds (LC50=2.93 µg/mL and the lowest by Litsea glutinosa leaves (LC50=114.71 µg/mL in comparison with standard vincristine sulphate (LC50=2.04 µg/mL. Among the plants, the plants traditionally used in different cancer and microbial treatments showed highest cytotoxicity. The results support their ethnomedicinal uses and require advanced investigation to elucidate responsible compounds as well as their mode of action.

  4. Cytotoxicity Potentials of Eleven Bangladeshi Medicinal Plants

    Science.gov (United States)

    Haque, Tania; Akter, Mahfuja; Akter, Subarna; Jhumur, Afrin

    2014-01-01

    Various forms of cancer are rising all over the world, requiring newer therapy. The quest of anticancer drugs both from natural and synthetic sources is the demand of time. In this study, fourteen extracts of different parts of eleven Bangladeshi medicinal plants which have been traditionally used for the treatment of different types of carcinoma, tumor, leprosy, and diseases associated with cancer were evaluated for their cytotoxicity for the first time. Extraction was conceded using methanol. Phytochemical groups like reducing sugars, tannins, saponins, steroids, gums, flavonoids, and alkaloids were tested using standard chromogenic reagents. Plants were evaluated for cytotoxicity by brine shrimp lethality bioassay using Artemia salina comparing with standard anticancer drug vincristine sulphate. All the extracts showed potent to moderate cytotoxicity ranging from LC50 2 to 115 µg/mL. The highest toxicity was shown by Hygrophila spinosa seeds (LC50 = 2.93 µg/mL) and the lowest by Litsea glutinosa leaves (LC50 = 114.71 µg/mL) in comparison with standard vincristine sulphate (LC50 = 2.04 µg/mL). Among the plants, the plants traditionally used in different cancer and microbial treatments showed highest cytotoxicity. The results support their ethnomedicinal uses and require advanced investigation to elucidate responsible compounds as well as their mode of action. PMID:25431796

  5. Initial non-participation and loss to follow-up in a Danish youth cohort

    DEFF Research Database (Denmark)

    Winding, Trine Nøhr; Andersen, Johan H; Labriola, Merete;

    2014-01-01

    BACKGROUND: Initial non-participation and loss to follow-up in the Danish youth cohort Vestliv could introduce selection bias of the measured risk estimates. OBJECTIVE: To investigate the impact of initial non-participation and loss to follow-up on the validity of descriptive measures and selected...... better school abilities and came more often from homes with two adults, higher income or higher educational level. These differences increased at subsequent follow-ups. The effect of initial non-participation on the ORs was modest with most RORs being close to one. Loss to follow-up led to larger...... variations in the RORs ranging from 0.77 to 1.62 although for most estimates, the bias was minor. None of the measured RORs were statistically different from one indicating no significant bias. CONCLUSIONS: Although certain characteristics were related to those who initially chose to participate...

  6. Compactifications of the eleven-dimensional supermembrane

    NARCIS (Netherlands)

    Bergshoeff, E.; Duff, M.J.; Pope, C.N.; Sezgin, E.

    1989-01-01

    We construct new vacua for the eleven-dimensional supermembrane in which spacetime is the product of four-dimensional anti-de Sitter space and a compact seven-dimensional Einstein space, and the membrane is a sphere of non-zero radius in the anti-de Sitter space. In one class of solution the radius

  7. Observed and forecast flood-inundation mapping application-A pilot study of an eleven-mile reach of the White River, Indianapolis, Indiana

    Science.gov (United States)

    Kim, Moon H.; Morlock, Scott E.; Arihood, Leslie D.; Kiesler, James L.

    2011-01-01

    Near-real-time and forecast flood-inundation mapping products resulted from a pilot study for an 11-mile reach of the White River in Indianapolis. The study was done by the U.S. Geological Survey (USGS), Indiana Silver Jackets hazard mitigation taskforce members, the National Weather Service (NWS), the Polis Center, and Indiana University, in cooperation with the City of Indianapolis, the Indianapolis Museum of Art, the Indiana Department of Homeland Security, and the Indiana Department of Natural Resources, Division of Water. The pilot project showed that it is technically feasible to create a flood-inundation map library by means of a two-dimensional hydraulic model, use a map from the library to quickly complete a moderately detailed local flood-loss estimate, and automatically run the hydraulic model during a flood event to provide the maps and flood-damage information through a Web graphical user interface. A library of static digital flood-inundation maps was created by means of a calibrated two-dimensional hydraulic model. Estimated water-surface elevations were developed for a range of river stages referenced to a USGS streamgage and NWS flood forecast point colocated within the study reach. These maps were made available through the Internet in several formats, including geographic information system, Keyhole Markup Language, and Portable Document Format. A flood-loss estimate was completed for part of the study reach by using one of the flood-inundation maps from the static library. The Federal Emergency Management Agency natural disaster-loss estimation program HAZUS-MH, in conjunction with local building information, was used to complete a level 2 analysis of flood-loss estimation. A Service-Oriented Architecture-based dynamic flood-inundation application was developed and was designed to start automatically during a flood, obtain near real-time and forecast data (from the colocated USGS streamgage and NWS flood forecast point within the study reach

  8. Estudio de la no participación en el programa de prevención de cáncer de mama en la ciudad de Valencia Study of non-participation in the breast cancer screening program in the city of Valencia [Spain

    Directory of Open Access Journals (Sweden)

    M. Alcaraz

    2002-06-01

    alta, que llevan THS y de nivel cultural medio o alto tienen mayor probabilidad de estar estudiadas. Conclusiones: El perfil de las mujeres que no participan, pertenece, por un lado, a la clase social media o alta, que toman THS y que están siendo revisadas por otros servicios sanitarios, y por otro, a un grupo de mujeres con nivel socioeconómico bajo y cuyo motivo de no participación es por temor o dificultades de horario.Aim: To determine the reasons for non-participation of women in a breast cancer screening program. Methods: We performed an observational, cross-sectional study in women who were invited to participate in the breast cancer screening program in the city of Valencia and who failed to attend. The women were interviewed in their homes through a questionnaire consisting of 25 questions grouped as follows: knowledge of the program, reasons for nonparcitipation, attitudes or beliefs and characteristics of the interviewees (socioeconomic and educational variables and age. A descriptive analysis was performed. Differences in the characteristics of women were evaluated thorugh bivariate analysis. Multivariate analysis was performed through logistic regression. Results: A total of 783 addreses were used, 411 questionnaires were completed and 361 were analyzed. The 50 questionnaires used in the pilot study were excluded because, as a consequence of this study, the questionnaire had been modified. Most of the women (93,4% (CI: 90.3-95.7 remembered having an appointment. The main reason for not attending was being screened in another health service in 48.8% (CI: 43.6-53.9, followed by various personal reasons in 16.1% (CI: 12.3-19.9 and inability to keep the appointment at the specified time in 15.5% (CI: 11.8-19.2. Comparison of women in the middle and upper social classes with those in the lower classes revealed important differences. Middle and upper class women had a higher probability of knowing about the program and of being on hormone replacement therapy

  9. Genetic diversity of eleven European pig breeds

    Directory of Open Access Journals (Sweden)

    Foulley Jean-Louis

    2000-03-01

    Full Text Available Abstract A set of eleven pig breeds originating from six European countries, and including a small sample of wild pigs, was chosen for this study of genetic diversity. Diversity was evaluated on the basis of 18 microsatellite markers typed over a total of 483 DNA samples collected. Average breed heterozygosity varied from 0.35 to 0.60. Genotypic frequencies generally agreed with Hardy-Weinberg expectations, apart from the German Landrace and Schwäbisch-Hällisches breeds, which showed significantly reduced heterozygosity. Breed differentiation was significant as shown by the high among-breed fixation index (overall FST = 0.27, and confirmed by the clustering based on the genetic distances between individuals, which grouped essentially all individuals in 11 clusters corresponding to the 11 breeds. The genetic distances between breeds were first used to construct phylogenetic trees. The trees indicated that a genetic drift model might explain the divergence of the two German breeds, but no reliable phylogeny could be inferred among the remaining breeds. The same distances were also used to measure the global diversity of the set of breeds considered, and to evaluate the marginal loss of diversity attached to each breed. In that respect, the French Basque breed appeared to be the most "unique" in the set considered. This study, which remains to be extended to a larger set of European breeds, indicates that using genetic distances between breeds of farm animals in a classical taxonomic approach may not give clear resolution, but points to their usefulness in a prospective evaluation of diversity.

  10. Age, sex, and socio-economic status affect the incidence of pediatric spinal cord injury: an eleven-year national cohort study.

    Directory of Open Access Journals (Sweden)

    Li-Chien Chien

    Full Text Available BACKGROUND: Few studies focus on pediatric spinal cord injury (SCI and there is little information regarding the cause, anatomic level, and high risk population of SCI in children. This study aims to investigate the incidence and risk factors of pediatric SCI. METHODS: A nationwide cohort of 8.7 million children aged<18 years in an 11-year period was analyzed for causes, age at injury, anatomic sites, disability, and familial socio-economic factors. Incidence rates and Cox regression analysis were conducted. RESULTS: A total of 4949 SCI patients were analyzed. The incidence rates of cervical, thoracic, lumbar, and other SCI were 4.06, 0.34, 0.75, and 0.85 per 100,000 person-years, respectively. The proportional composition of gender, age, and socio-economic status of SCI patients were significantly different than those of non-SCI patients (all p<0.001. Male children were significantly more likely to have SCI than females in both the cervical and the other SCI groups [Incidence rate ratio (IRR = 2.03 and 1.52; both p<0.001]. Young adults and teenagers were also significantly more likely to have SCI than pre-school age children in the cervical SCI (IRR = 28.55 and 10.50, both p<0.001 and other SCI groups (IRR = 18.8 and 7.47, both p<0.001. Children in families of lower socio-economic status were also significantly more likely to have SCI (p<0.05. CONCLUSIONS: In the pediatric population, the overall SCI incidence rate is 5.99 per 100,000 person-years, with traumatic cervical SCI accounting for the majority. The incidence rate increases abruptly in male teenagers. Gender, age, and socio-economic status are independent risk factors that should be considered.

  11. Ten years after acquiring an HIV-1 infection: a study in a cohort of eleven neonates infected by aliquots from a single plasma donation.

    Science.gov (United States)

    van den Berg, H; Gerritsen, E J; van Tol, M J; Dooren, L J; Vossen, J M

    1994-02-01

    We present data from a 10-year follow-up study of 11 children who had been infected in the neonatal period by small aliquots of plasma from a single donation. Three of the children died within the first 2.5 years of life, 5 other children died between 6.2 and 11 years after infection and 3 are alive at present. The latter children are classified as P1B (asymptomatic), P2A (non-specific findings) and P2B (neurological changes). All infected children showed progressive decline of cellular immunity. Immunoglobulin levels in serum were increased in the majority of children for prolonged periods and homogeneous immunoglobulin components were present. The severity of the disease was related neither to the clinical condition of the infants in the neonatal period nor to the volume of transfused plasma, the interval between freezing and thawing of the plasma, gestational age at birth and age at transfusion. Coinciding infections with other viruses had no impact on disease progression during the follow-up period of 10 years.

  12. The Non-Participation Survey: Understanding Why High School Students Choose Not to Eat School Lunch

    Science.gov (United States)

    Asperin, Amelia Estepa; Nettles, Mary Frances; Carr, Deborah H.

    2010-01-01

    Purpose/Objectives: The purpose of this project was to develop and validate a survey that will enable school nutrition (SN) directors and managers to identify and address issues affecting the non-participation of high school students in the National School Lunch Program (NSLP). Methods: The research was conducted in two phases. Qualitative data…

  13. Null structure groups in eleven dimensions

    CERN Document Server

    Cariglia, M; Conamhna, Oisin A. P. Mac

    2004-01-01

    We classify all the structure groups which arise as subgroups of the isotropy group, $(Spin(7)\\ltimes\\mathbb{R}^8)\\times\\mathbb{R}$, of a single null Killing spinor in eleven dimensions. We construct the spaces of spinors fixed by these groups. We determine the conditions under which structure subgroups of the maximal null strucuture group $(Spin(7)\\ltimes\\mathbb{R}^8)\\times\\mathbb{R}$ may also be embedded in SU(5), and hence the conditions under which supersymmetric spacetime admits only null, or both timelike and null, Killing spinors. This concludes, for spacetimes admitting at least one null Killing spinor, the first, purely algebraic, phase of the refined G-structure classification of supersymmetric spacetimes in eleven dimensions, the objective of which is the derivation of the general local bosonic solution of the Killing spinor equation of eleven dimensional supergravity. Finally, we discuss how the second phase of the classification, involving the direct analysis of the Killing spinor equation, may b...

  14. Comparison of Characteristics and Outcomes of Trial Participants and Non-participants: Example of Blood and Marrow Transplant Clinical Trials Network (BMT-CTN) 0201 Trial

    Science.gov (United States)

    Khera, Nandita; Majhail, Navneet S.; Brazauskas, Ruta; Wang, Zhiwei; He, Naya; Aljurf, Mahmoud D.; Akpek, Görgün; Atsuta, Yoshiko; Beattie, Sara; Bredeson, Christopher N.; Burns, Linda J.; Dalal, Jignesh D.; Freytes, César O.; Gupta, Vikas; Inamoto, Yoshihiro; Lazarus, Hillard M.; LeMaistre, Charles F.; Steinberg, Amir; Szwajcer, David; Wingard, John R.; Wirk, Baldeep; Wood, William A.; Joffe, Steven; Hahn, Theresa E.; Loberiza, Fausto R.; Anasetti, Claudio; Horowitz, Mary M.; Lee, Stephanie J.

    2015-01-01

    BACKGROUND Controversy surrounds the question of whether clinical trial participants have better outcomes than comparable patients who are not treated on a trial. We explored this question using a recent large, randomized, multi-center study comparing peripheral blood (PB) with bone marrow (BM) transplantation from unrelated donors (URD), conducted by the Blood and Marrow Transplant Clinical Trials Network (BMT CTN). METHODS AND FINDINGS We compared characteristics and outcomes of study participants (n=494) and non-participants (n=1384) who appeared eligible and received similar treatment without enrolling on the BMT CTN trial at participating centers during the study time-period. Data were obtained from the Center for International Blood and Marrow Transplant Research. Outcomes were compared between the two groups using Cox proportional hazards regression models. No significant differences in age, sex and disease distribution, race/ ethnicity, HLA matching, comorbidities and interval from diagnosis to HCT were seen between the participants and non-participants. Non-participants were more likely to have lower performance status, lower-risk disease, and older donors, and to receive myeloablative conditioning and anti-thymocyte globulin. Non-participants were also more likely to receive PB grafts, the intervention tested in the trial (66% vs. 50% ptransplant-related mortality, and incidences of acute or chronic GVHD were comparable between the two groups though relapse was higher (HR 1.22, 95% CI 1.02–1.46, p=0.028) in non-participants. CONCLUSION Despite differences in certain baseline characteristics, survival was comparable between study participants and non-participants. The results of the BMT CTN trial appear generalizable to the population of trial-eligible patients. PMID:26071866

  15. Non-participation in systematic screening for osteoporosis-the ROSE trial

    DEFF Research Database (Denmark)

    Rothmann, M J; Möller, S; Holmberg, T

    2017-01-01

    education, lower income, and higher comorbidity. In the intervention group, ticking "not interested in DXA" in the questionnaire was associated with older age, living alone, and low self-perceived fracture risk. Women with previous fracture or history of parental hip fracture were more likely to accept......Population-based screening for osteoporosis is still controversial and has not been implemented. Non-participation in systematic screening was evaluated in 34,229 women age 65-81 years. Although participation rate was high, non-participation was associated with comorbidity, aging other risk factors...... for fractures, and markers of low social status, e.g., low income, pension, and living alone. A range of strategies is needed to increase participation, including development of targeted information and further research to better understand the barriers and enablers in screening for osteoporosis. INTRODUCTION...

  16. Rotational Spectroscopy Unveils Eleven Conformers of Adrenaline

    Science.gov (United States)

    Cabezas, C.; Cortijo, V.; Mata, S.; Lopez, J. C.; Alonso, J. L.

    2013-06-01

    Recent improvements in our LA-MB-FTMW instrumentation have allowed the characterization of eleven and eight conformers for the neurotransmitters adrenaline and noradrenaline respectively. The observation of this rich conformational behavior is in accordance with the recent observation of seven conformers for dopamine and in sharp contrast with the conformational reduction proposed for catecholamines. C. Cabezas, I. Peña, J. C. López, J. L. Alonso J. Phys. Chem. Lett. 2013, 4, 486. H. Mitsuda, M. Miyazaki, I. B. Nielsen, P. Carcabal,C. Dedonder, C. Jouvet, S. Ishiuchi, M. Fujii J. Phys. Chem. Lett. 2010, 1, 1130.

  17. Eleven theses of general systems theory (GST)

    Energy Technology Data Exchange (ETDEWEB)

    Waelchli, F. [Defense Systems Management College, Fort Belvoir, VA (United States)

    1992-12-31

    This paper chronicles an effort to distill and order (for purposes of discussion and elaboration) frequently mentioned and significant ideas encountered in the literature of General Systems theory (GST). The product is a set of eleven theses, representing the author`s selection and collation of seminal and recurrent GST themes. The author argues that attention to theory could aid the effort to develop practical applications of systems thinking. (Remember that a thesis is a statement or assertion, offered originally without proof, as the basis for an argument, discussion, or empirical test). 10 refs.

  18. Spin(7) structures in eleven dimensions

    CERN Document Server

    Cariglia, M; Cariglia, Marco; Conamhna, Oisin A. P. Mac

    2004-01-01

    We derive, for spacetimes admitting a Spin(7) structure, the general local bosonic solution of the Killing spinor equation of eleven dimensional supergravity. The metric, four form and Killing spinors are determined explicitly, up to an arbitrary eight-manifold of Spin(7) holonomy. It is sufficient to impose the Bianchi identity and one particular component of the four form field equation to ensure that the solution of the Killing spinor equation also satisfies all the field equations, and we give these conditions explicitly.

  19. Randomized intervention trial on preventive home visits to older people: baseline and follow-up characteristics of participants and non-participants

    DEFF Research Database (Denmark)

    Vass, Mikkel; Avlund, Kirsten; Hendriksen, Carsten

    2007-01-01

    of municipality employees) was done at municipality level. In total 5,788 home-dwelling 75- and 80-year-olds living in these municipalities were invited to participate in the study. Written consent was obtained from 4,060 persons (participation rate 71%). RESULTS: During five-year follow-up non-participants had...

  20. Spencer cohomology and eleven-dimensional supergravity

    CERN Document Server

    Figueroa-O'Farrill, José

    2015-01-01

    We recover the classification of the maximally supersymmetric bosonic backgrounds of eleven-dimensional supergravity by Lie algebraic means. We classify all filtered deformations of the $\\mathbb Z$-graded subalgebras $\\mathfrak{h}=\\mathfrak{h}_{-2}\\oplus\\mathfrak{h}_{-1}\\oplus\\mathfrak{h}_{0}$ of the Poincar\\'e superalgebra $\\mathfrak{g}=\\mathfrak{g}_{-2}\\oplus\\mathfrak{g}_{-1}\\oplus\\mathfrak{g}_{0}=V\\oplus S\\oplus \\mathfrak{so}(V)$ which differ only in zero degree, that is $\\mathfrak{h}_0\\subset\\mathfrak{g}_0$ and $\\mathfrak{h}_j=\\mathfrak{g}_j$ for $j<0$. Aside from the Poincar\\'e superalgebra itself and its $\\mathbb Z$-graded subalgebras, there are only three other Lie superalgebras, which are the symmetry superalgebras of the non-flat maximally supersymmetric backgrounds. In passing we identify the gravitino variation with (a component of) a Spencer cocycle.

  1. Socioeconomic differences in smoking in an urban Swedish population. The bias introduced by non-participation in a mailed questionnaire

    DEFF Research Database (Denmark)

    Boström, G; Hallqvist, J; Haglund, B J

    1993-01-01

    a higher prevalence of daily smoking in all sub-groups. This effect of the efforts to reduce non-participation differed socially. The prevalence of smoking for men, 40-64 years of age, who were reached by telephone was 60.3%. Male professionals and intermediate non-manual workers, 40-64 years of age...... reached by telephone had a prevalence of smoking, which was twice as high as for the responders of the questionnaire (62.5 and 26.8%, respectively). In the younger age-group, non-responders had the same socioeconomic pattern in smoking as the responders. Independent of socioeconomic group......Stockholm Health of the Population Study is a cross-sectional study carried out from 1984-85. Postal questionnaires, telephone interviews and health interviews were used to get information from a sample of 5,199 persons, 18-64 years of age, on health status, risk exposures, healthcare consumption...

  2. Knowledge Creation Systems in Seven-Eleven Japan

    Institute of Scientific and Technical Information of China (English)

    SENOO Dai

    2004-01-01

    Japanese convenience store chain Seven-Eleven Japan (hereinafter "SEJ") has been profitable for 30 years by constantly anticipating changing trends regardless of the severe business environment. In this paper, the knowledge creation process and its supportive systems in SEJ to examine how information system can support knowledge creation are described. Using case study method, the knowledge creation theory is applied to SE J, and the results show that facilitating "dialogue" and reinforcing "creative routine" might be the most important functions of information system to support knowledge creation.

  3. Interstitial pregnancies' diagnosis and management: an eleven cases series.

    Science.gov (United States)

    Surbone, Anna; Cottier, Olivier; Vial, Yvan; Francini, Katyuska; Hohlfeld, Patrick; Achtari, Chahin

    2013-02-27

    Interstitial pregnancy represents 2% of ectopic pregnancies, but it is a highly morbid condition with a 2.5% of maternal mortality. Its diagnostic and therapeutic management remains controversial. The aim of this review is to describe the management of interstitial pregnancy in our institution between 2001 and 2011 and to define some general rules for the clinical practice. Single institution retrospective study. Eleven women were treated for interstitial pregnancy. The median age was 33 years and the median gestity was 4. Seven patients had a history of gynaecological surgery and four interstitial pregnancies followed in vitro fertilisation. The diagnosis was made at a median gestational age of seven weeks with a median beta-HCG level of 5,838 U/l. Six of the eleven patients received an initial treatment with intracornual methotrexate, three with intramuscular methotrexate and two with surgery. The median time to beta-HCG resolution was 58 days. Three of the eleven patients needed a second line treatment: two after intramuscular methotrexate and one after intracornual methotrexate. Six patients had further pregnancies and delivered by caesarean section. A high prevalence of previous ectopic pregnancies, gynaecological surgery and of pregnancies resulting from in vitro fertilisation was observed. The earliness of the diagnosis was the factor that allowed a conservative treatment in most cases. Beta-HCG level follow up was fundamental in allowing a second line therapy but beta-HCG can persist over a long period of time and this must be taken into account due to its possible psychological impact. Intracornual methotrexate seems to be more efficacious than intramuscular methotrexate in our series.

  4. National South African HIV prevalence estimates robust despite substantial test non-participation

    Directory of Open Access Journals (Sweden)

    Guy Harling

    2017-07-01

    Full Text Available Background. South African (SA national HIV seroprevalence estimates are of crucial policy relevance in the country, and for the worldwide HIV response. However, the most recent nationally representative HIV test survey in 2012 had 22% test non-participation, leaving the potential for substantial bias in current seroprevalence estimates, even after controlling for selection on observed factors. Objective. To re-estimate national HIV prevalence in SA, controlling for bias due to selection on both observed and unobserved factors in the 2012 SA National HIV Prevalence, Incidence and Behaviour Survey. Methods. We jointly estimated regression models for consent to test and HIV status in a Heckman-type bivariate probit framework. As selection variable, we used assigned interviewer identity, a variable known to predict consent but highly unlikely to be associated with interviewees’ HIV status. From these models, we estimated the HIV status of interviewed participants who did not test. Results. Of 26 710 interviewed participants who were invited to test for HIV, 21.3% of females and 24.3% of males declined. Interviewer identity was strongly correlated with consent to test for HIV; declining a test was weakly associated with HIV serostatus. Our HIV prevalence estimates were not significantly different from those using standard methods to control for bias due to selection on observed factors: 15.1% (95% confidence interval (CI 12.1 - 18.6 v. 14.5% (95% CI 12.8 - 16.3 for 15 - 49-year-old males; 23.3% (95% CI 21.7 - 25.8 v. 23.2% (95% CI 21.3 - 25.1 for 15 - 49-year-old females. Conclusion. The most recent SA HIV prevalence estimates are robust under the strongest available test for selection bias due to missing data. Our findings support the reliability of inferences drawn from such data.

  5. Adjusting HIV prevalence estimates for non-participation: an application to demographic surveillance

    Directory of Open Access Journals (Sweden)

    Mark E. McGovern

    2015-11-01

    % among those who participated in testing, and 18% estimated with imputation. We provide new confidence intervals that correct for the fact that the relationship between testing and HIV status is unknown and requires estimation. Conclusions: We confirm the feasibility and value of adopting selection models to account for missing data in population-based HIV surveys and surveillance systems. Elements of survey design, such as interviewer identity, present the opportunity to adopt this approach in routine applications. Where non-participation is high, true confidence intervals are much wider than those generated by standard approaches to dealing with missing data suggest.

  6. The influence of eleven Ps: An internal marketing and brand ...

    African Journals Online (AJOL)

    The influence of eleven Ps: An internal marketing and brand awareness perspective ... their loyalty and commitment to deliver service excellence to customers. ... the 11 internal marketing mix elements (product, price, place, promotion, people, ...

  7. Nyttige og mindre nyttige lærerkommentarer – slik elevene ser det

    Directory of Open Access Journals (Sweden)

    Agnete Andersen Bueie

    2016-06-01

    Full Text Available Til tross for en etablert oppfatning av tilbakemeldingers betydning for læring, er elevenes oppfatning og vurdering av tilbakemelding et lite utforsket område. Hvilke tilbakemeldinger synes elevene er nyttige? Denne artikkelen presenterer en studie som undersøker hvilke lærerkommentarer elever på ungdomstrinnet finner nyttige og mindre nyttige. Det empiriske materialet består av en spørreundersøkelse besvart av 159 elever fra 10. trinn i norsk ungdomsskole på grunnlag av en spesielt tilrettelagt tilbakemeldingssituasjon. Resultatene av spørreundersøkelsen viser at elevene foretrekker lærerkommentarer på globale tekstnivå (som innhold, ideer og sjanger og kommentarer som spesifikt forklarer hva eleven bør gjøre og hvorfor. Elevene setter pris på ros, men også kritiske kommentarer vurderes som nyttige. Resultatene drøftes med bakgrunn i tidligere forskning på området.

  8. Recruitment and Reasons for Non-Participation in a Family-Coping-Orientated Palliative Home Care Trial (FamCope)

    DEFF Research Database (Denmark)

    Ammari, Anne Birgitte Hjuler; Hendriksen, Carsten; Rydahl-Hansen, Susan

    2015-01-01

    professionals. However, an unexpectedly high number of families declined participation in the trial. We describe and discuss the recruitment strategy and patient reported reasons for non-participation to add to the knowledge about what impedes recruitment and to identify the factors that influence willingness...... to participate in research aimed at family coping early in the palliative care trajectory. Patients with advanced cancer and their closest relative were recruited from medical, surgical, and oncological departments. Reasons for non-participation were registered and characteristics of participants and non...... to affect willingness to receive a family-coping-orientated care approach and impeded recruitment to this trial. Our findings can be used in further research and in clinical practice in order to construct interventions and target relevant populations for early family-coping-orientated palliative care....

  9. Black-hole binaries go to eleven orbits

    CERN Document Server

    Sperhake, Ulrich; Mueller, Doreen; Sopuerta, Carlos F

    2010-01-01

    We analyse an eleven-orbit inspiral of a non-spinning black-hole binary with mass ratio q=M1/M2=4. The numerically obtained gravitational waveforms are compared with post-Newtonian (PN) predictions including several sub-dominant multipoles up to multipolar indices (l=5,m=5). We find that (i) numerical and post-Newtonian predictions of the phase of the (2,2) mode accumulate a phase difference of about 0.35 rad at the PN cut off frequency 0.1 for the Taylor T1 approximant; (ii) in contrast to previous studies of equal-mass and specific spinning binaries, we find the Taylor T4 approximant to agree less well with numerical results, provided the latter are extrapolated to infinite extraction radius; (iii) extrapolation of gravitational waveforms to infinite extraction radius is particularly important for subdominant multipoles with l unequal m; (iv) 3PN terms in post-Newtonian multipole expansions significantly improve the agreement with numerical predictions for sub-dominant multipoles.

  10. Paracoccidioidomycosis of the male genital tract. Report of eleven cases and a review of Brazilian literature

    Directory of Open Access Journals (Sweden)

    SEVERO Luiz Carlos

    2000-01-01

    Full Text Available Eleven cases of involvement of the genital tract in paracoccidioidomycosis were collected in a retrospective study of the clinical records of 683 patients seen in Porto Alegre, Rio Grande do Sul, Brazil. These cases are herein summarily reported. Eighteen similar cases were gathered in review of the Brazilian literature. Obtained data are discussed.

  11. Analisis Industri pada Ritel Convenience Store: Kasus 7-Eleven (Sevel

    Directory of Open Access Journals (Sweden)

    Son Wandrial

    2013-05-01

    Full Text Available 7-Eleven, a Japanese retailer is very popular and loved in Jakarta. 7-Eleven or commonly abbreviated to Sevel is now reaping a lot of fans because of the concept of 7-Eleven Indonesia, found only in Indonesia. With the rising middle classes in Indonesia, 7-Eleven becomes a luxurious place for hanging-out but affordable. Consequently, it is attracting the interest of investors to make such a kind of convenience store like Sevel, and it is likely the competition in this sector will be increasingly fierce. PT. Modern’s initial plans are to focus onopening stores in Jakarta, targeting densely-populated commercial and office areas, to offer Indonesian workersa convenient place to shop for lunch, snacks, and emergency items. The company’s goal is to focus on opening stores in Jakarta in its first years of operation. Other major cities, such as Bandung, Semarang, and Surabaya offer for future expansion opportunities. The objective of this article is to describe the competitive condition in convenience store industries using Porter’s Five Forces model. Although the competition is fierce andunfavorable industry condition, Sevel is still leading and dominating the convenience store market in Indonesia.

  12. Factors associated with non-participation and drop-out in a lifestyle intervention for workers with an elevated risk of cardiovascular disease

    NARCIS (Netherlands)

    Groeneveld, I.F.; Proper, K.I.; Beek, A.J. van der; Hildebrandt, V.H.; Mechelen, W. van

    2009-01-01

    Background: Non-response and drop-out are problems that are commonly encountered in health promotion trials. Understanding the health-related characteristics of non-participants and drop-outs and the reasons for non-participation and drop-out may be beneficial for future intervention trials.

  13. Using SNA to map participation and non-participation in vulnerable populations

    DEFF Research Database (Denmark)

    Hindhede, Anette Lykke

    investigation of social networks in a deprived area, the study aimed at identifying social networks of residents who participated in various community-based activities as well as informal groups. Fisher’s (1982) theoretical definition of relation was used and a scheme for coding respondents on the adequacy...... of their social support was constructed. Data showed that the area was characterised by a variety of cultural backgrounds, and ways of living everyday life. Participation in the activities driven at the municipal level was among the relatively resourceful ethnic Danes. The paper discusses the difficulties...

  14. Comparison of Eleven Heavy Metals in Moringa Oleifera Lam. Products.

    Science.gov (United States)

    Limmatvapirat, C; Limmatvapirat, S; Charoenteeraboon, J; Wessapan, C; Kumsum, A; Jenwithayaamornwech, S; Luangthuwapranit, P

    2015-01-01

    Eleven heavy metals in various products of Moringa oleifera were analyzed to determine eleven heavy metals (Al, As, Cd, Cr, Cu, Fe, Pb, Mn, Hg, Ni, and Zn) using Inductively Coupled Plasma-Mass Spectrometry. The products of M. oleifera were purchased in Nakhon Pathom, Thailand. All products were digested with nitric acid solution before determining the concentrations of heavy metals. The recoveries of all heavy metals were found to be in the range of 99.89-103.05%. Several criteria such as linearity, limits of detection, limits of quantification, specificity, precision under repeatability conditions and intermediate precision reproducibility were evaluated. Results indicate that this method could be used in the laboratory for determination of eleven heavy metals in M. oleifera products with acceptable analytical performance. The results of analysis showed that the highest concentrations of As, Cr, Hg, and Mn were found in tea leaves while the highest concentrations of Al, Cd, Cu, Fe, Ni, Pb, and Zn were found in leaf capsules. Continuous monitoring of heavy metals in M. oleifera products is crucial for consumer health.

  15. Comparison of eleven heavy metals in moringa oleifera lam. products

    Directory of Open Access Journals (Sweden)

    C Limmatvapirat

    2015-01-01

    Full Text Available Eleven heavy metals in various products of Moringa oleifera were analyzed to determine eleven heavy metals (Al, As, Cd, Cr, Cu, Fe, Pb, Mn, Hg, Ni, and Zn using Inductively Coupled Plasma-Mass Spectrometry. The products of M. oleifera were purchased in Nakhon Pathom, Thailand. All products were digested with nitric acid solution before determining the concentrations of heavy metals. The recoveries of all heavy metals were found to be in the range of 99.89-103.05%. Several criteria such as linearity, limits of detection, limits of quantification, specificity, precision under repeatability conditions and intermediate precision reproducibility were evaluated. Results indicate that this method could be used in the laboratory for determination of eleven heavy metals in M. oleifera products with acceptable analytical performance. The results of analysis showed that the highest concentrations of As, Cr, Hg, and Mn were found in tea leaves while the highest concentrations of Al, Cd, Cu, Fe, Ni, Pb, and Zn were found in leaf capsules. Continuous monitoring of heavy metals in M. oleifera products is crucial for consumer health.

  16. Reasons for women’s non-participation in follow-up screening after gestational diabetes

    DEFF Research Database (Denmark)

    Hyldgaard Nielsen, Jane; Olesen, Christinna Rebecca; Kristiansen, Tine Mechlenborg

    2016-01-01

    BACKGROUND: Women whose pregnancy was complicated by gestational diabetes have a 7-fold higher risk of developing diabetes, primarily type 2. Early detection can prevent or delay the onset of late complications, for which follow-up screening is important. This study investigated the extent...... of participation in follow-up screening and the possible consequences of nonattendance in the Region of North Jutland, Denmark. METHOD: In Danish national registers covering the years 1994-2011 we identified 2171 birthing women whose pregnancy was complicated by first-time gestational diabetes. Control visits...... to general practitioners and biochemical departments after giving birth were charted. Following national guidelines we defined four intervals for assessment of participation in follow-up screening. Diagnosis of diabetes or treatment with glucose-lowering agents after giving birth were also identified...

  17. Eat Smart! Ontario's Healthy Restaurant Program: focus groups with non-participating restaurant operators.

    Science.gov (United States)

    Dwyer, John J M; Macaskill, Lesley A; Uetrecht, Connie L; Dombrow, Carol

    2004-01-01

    Eat Smart! Ontario's Healthy Restaurant Program is a standard provincial health promotion program. Public health units give an award of excellence to restaurants that meet nutrition, food safety, and non-smoking seating standards. The purpose of this study was to determine why some restaurant operators have not applied to participate in the program, and how to get them to apply. Four focus group interviews were conducted with 35 operators who didn't apply to participate. The analysis of responses yielded various themes. The participants' perceived barriers to participation were misunderstandings about how to qualify for the program, lack of time, concern about different non-smoking bylaw requirements, and potential loss of revenue. Their perceived facilitators to participation were convenience of applying to participate, franchise executives' approval to participate, a 100% non-smoking bylaw, flexibility in the assessment of restaurants, the opportunity for positive advertising, alternative payment for food handler training, and customer demand. Program staff can use the findings to develop and use strategies to encourage participation.

  18. Factors Associated with Non-Participation and Non-Adherence in Directly Observed Mass Drug Administration for Malaria in The Gambia.

    Directory of Open Access Journals (Sweden)

    Susan Dierickx

    Full Text Available The potential benefits of Mass Drug Administration (MDA for malaria elimination are being considered in several malaria endemic countries where a decline in malaria transmission has been reported. For this strategy to work, it is important that a large proportion of the target population participates, requiring an in-depth understanding of factors that may affect participation and adherence to MDA programs.This social science study was ancillary to a one-round directly observed MDA campaign with dihydroartemisinin-piperaquine, carried out in 12 villages in rural Gambia between June and August 2014. The social science study employed a mixed-methods approach combining qualitative methods (participant observation and in-depth interviewing and quantitative methods (structured follow-up interviews among non-participating and non-adhering community members.Of 3942 people registered in the study villages, 67.9% adhered to the three consecutive daily doses. For the remaining villagers, 12.6% did not attend the screening, 3.5% was not eligible and 16% did not adhere to the treatment schedule. The main barriers for non-participation and adherence were long and short-term mobility of individuals and specific subgroups, perceived adverse drug reactions and rumors, inconveniences related to the logistics of MDA (e.g. waiting times and the perceived lack of information about MDA.While, there was no fundamental resistance from the target communities, adherence was 67.9%. This shows the necessity of understanding local perceptions and barriers to increase its effectiveness. Moreover, certain of the constraining factors were socio-spatially clustered which might prove problematic since focal areas of residual malaria transmission may remain allowing malaria to spread to adjacent areas where transmission had been temporarily interrupted.

  19. Using Social Network Analysis To Map Participation And Non-participation In Health Promotion and Community-building Among Vulnerable Populations

    DEFF Research Database (Denmark)

    Hindhede, Anette Lykke

    In empowerment and asset-based approaches to community development, the ability to change local residents’ perception of themselves and their neighbours from that of persons with needs that can only be met with the help of professionals to that of a more self-reliant group with assets...... and capacities for collective and collaborative problemsolving is seen as key to successful community building (Kretzmann and McKnight, 1993). By using social network analysis and Bourdieu’s definition of capital, this study aimed to identify patterns of participation and non-participation in a community......-building project aiming at increasing upward mobility and social capital within the area and increase equity in health. This presentation will outline the tensions and contradictions which accompany policies and interventions that seek to strengthen local communities as a means of promoting health. Emerging...

  20. Determination of the food consumption in eleven regions of the european community with a view to studying the radioactive contamination level: Methods used. Results of family enquiries; Determination des regimes alimentaires des populations de onze regions de la communaute europeenne en vue de l'etude des niveaux de contamination radioactive: Methodologie. Resultats des enquetes familiales

    Energy Technology Data Exchange (ETDEWEB)

    Cresta, M.; Lacourly, G. [Commissariat a l' Energie Atomique, Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1966-07-01

    In the present report are given the results obtained from food surveys carried out during the period 1963-1965 and involving 9000 families living in eleven regions spread out over the six European Community countries. A partial analysis of the results obtained covers a reduced sample of 3725 families; it makes it possible to fix the composition of the mean individual, monthly and annual food consumptions for each of the eleven regions. Details of the organisation of the survey, of the data processing methods and of the method of presenting the results are given in the first part of the report. the second part presents, in numerical table form, the consumption of various foodstuffs and the feeding principles for each region covered by the survey. Tables summarizing the data make it possible to compare the mean individual consumptions in the various regions studied. (author) [French] Dans le present rapport sont rassembles les premiers resultats des enquetes alimentaires effectuees pendant la periode 1963-1965, aupres de 9000 familles, dans onze regions reparties dans les six pays de la Communaute Europeenne. L'exploitation partielle des donnees obtenues porte sur un echantillon reduit a 3725 familles et permet d'etablir la composition du regime alimentaire moyen individuel, mensuel et annuel de chacune des onze regions. L'organisation des enquetes, la methode de traitement des donnees et l'expression des resultats sont exposees dans la premiere partie du rapport. La seconde reunit, sous forme de tableaux numeriques, les consommations des differents aliments et principes alimentaires par region d'enquetes. Des tableaux recapitulatifs permettent, en outre, une comparaison des consommations moyennes, individuelles des differentes regions etudiees. (auteur)

  1. Evolution of analogical reasoning in children: follow-up from six to eleven years old

    Directory of Open Access Journals (Sweden)

    Luis Fidel Abregú Tueros

    2009-10-01

    Full Text Available The aim of this study is to establish the time and period of development of Analogical Reasoning (AR and evaluate its independence and performance with respect to the age. We performed a longitudinal cohort study of two age groups and six annual follow-up phases from each one (2000-2005, 2001-2006 in six to eleven years-old children in the city of Huanuco (Peru with a sample of 167 children (first stage, and N=121 (sixth stage. The Raven’s progressive matrices test, coloured version, was applied individually without time limits. Results indicate that AR development occurs in a constant and late way from seven to eleven years-old children, and also that there is independence between the ability of AR and the children age. We discuss the importance of knowledge in the relationships between analogies topics, adjusted to the age, as a mediating factor in the development of AR.

  2. Optimizing Federal Fleet Vehicle Acquisitions: An Eleven-Agency FY 2012 Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Singer, M. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Daley, R. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2015-02-01

    This report focuses on the National Renewable Energy Laboratory's (NREL) fiscal year (FY) 2012 effort that used the NREL Optimal Vehicle Acquisition (NOVA) analysis to identify optimal vehicle acquisition recommendations for eleven diverse federal agencies. Results of the study show that by following a vehicle acquisition plan that maximizes the reduction in greenhouse gas (GHG) emissions, significant progress is also made toward the mandated complementary goals of acquiring alternative fuel vehicles, petroleum use reduction, and alternative fuel use increase.

  3. An Eleven-Year Retrospective Study of Endogenous Bacterial Endophthalmitis

    Directory of Open Access Journals (Sweden)

    Takashi Nishida

    2015-01-01

    Full Text Available Purpose. To determine the clinical features, microbial profiles, treatment outcomes, and prognostic factors for endogenous bacterial endophthalmitis (EBE. Methods. The medical records of 27 eyes of 21 patients diagnosed with EBE for 11 years were reviewed. Collected data included age, site of infection, visual acuities (VAs, microbial profiles, and treatment regimen. Results. The mean age was 68.5 years. Gram-positive organisms accounted for 76.2%, while gram-negative ones accounted for 19.0%. Staphylococcus aureus was the most common causative organism (52.3% of which 72.7% was methicillin-resistant S. aureus. A final VA of ≥20/40 was achieved in 44% and 20/200 or better was in 64%. Eyes with initial VA of ≥20/200 (P = 0.003 and focal involvements (P = 0.011 had significantly better final VA. Initial VA (P = 0.001 and the interval between onset of ocular symptoms and intravitreal antibiotic injection (P = 0.097 were associated with final VA in eyes receiving intravitreal antibiotics. Conclusions. EBE is generally associated with poor visual outcome; however the prognosis may depend on initial VA, extent of ocular involvement, and an interval between onset of ocular symptoms and intravitreal antibiotic injection. Early diagnosis and early intravitreal injection supplement to systemic antibiotics might lead to a relatively good visual outcome.

  4. An Eleven-Year Retrospective Study of Endogenous Bacterial Endophthalmitis

    Science.gov (United States)

    Nishida, Takashi; Ishida, Kyoko; Niwa, Yoshiaki; Kawakami, Hideaki; Mochizuki, Kiyofumi; Ohkusu, Kiyofumi

    2015-01-01

    Purpose. To determine the clinical features, microbial profiles, treatment outcomes, and prognostic factors for endogenous bacterial endophthalmitis (EBE). Methods. The medical records of 27 eyes of 21 patients diagnosed with EBE for 11 years were reviewed. Collected data included age, site of infection, visual acuities (VAs), microbial profiles, and treatment regimen. Results. The mean age was 68.5 years. Gram-positive organisms accounted for 76.2%, while gram-negative ones accounted for 19.0%. Staphylococcus aureus was the most common causative organism (52.3%) of which 72.7% was methicillin-resistant S. aureus. A final VA of ≥20/40 was achieved in 44% and 20/200 or better was in 64%. Eyes with initial VA of ≥20/200 (P = 0.003) and focal involvements (P = 0.011) had significantly better final VA. Initial VA (P = 0.001) and the interval between onset of ocular symptoms and intravitreal antibiotic injection (P = 0.097) were associated with final VA in eyes receiving intravitreal antibiotics. Conclusions. EBE is generally associated with poor visual outcome; however the prognosis may depend on initial VA, extent of ocular involvement, and an interval between onset of ocular symptoms and intravitreal antibiotic injection. Early diagnosis and early intravitreal injection supplement to systemic antibiotics might lead to a relatively good visual outcome. PMID:25802752

  5. Adolescent multiple personality disorder: a preliminary study of eleven cases.

    Science.gov (United States)

    Dell, P F; Eisenhower, J W

    1990-05-01

    The diagnostic features and treatment histories of 11 adolescents with multiple personality disorder (MPD) are presented. Clinical evaluation revealed that the majority of these adolescents manifested extremely variable school performance, disruptive behavior, trances, amnesias, mood swings, sharp changes in personality, apparent lying, voices heard in the head, and depression. All had a history of childhood trauma: Sexual abuse (73%), physical abuse (73%), and emotional abuse (82%). Seventy-three percent had a parent with a diagnosable dissociative disorder; 36% of the mothers had MPD. These adolescents had a mean number of 24.1 alter personalities and appear to have become multiple at a mean age of 3 years, 1 month. All patients had angry protector alters, depressed alters, scared alters, and child alters. Fifty-four percent of these cases have integrated during treatment or are progressing toward integration. The remaining cases dropped out of therapy.

  6. Pengaruh Komunikasi Pelayanan dan Kepuasan terhadap Loyalitas Pelanggan di 7-Eleven Buaran

    Directory of Open Access Journals (Sweden)

    Jerry Marcellinus Logahan

    2013-11-01

    Full Text Available This research was motivated by low communication in the business retail in terms of service from employees to customers. It influences the decline in customer satisfaction and leads to customer loyalty at a very low level. This study aims to identify and analyze the significance of the influence of customer service (X1 and customer satisfaction (X2 on customer loyalty (Y. Research was conducted in February - May 2013 held at 7-Eleven Buaran Jakarta. Research used quantitative method by using questionnaires filled directly by the visitors of 7-Eleven Buaran with a population of 19.920 people and a sample of 100 people, calculated using the Slovin formula. Validity test, reliability, normality, correlation, regression, hypothesis, and the determination carried out in this study using the data processed using SPSS (Statistical Product and Service Solutions version 16.0. Results indicated that customer service has significant influence by 14.6% on customer loyalty, customer satisfaction has a significant effect of 8.5% on customer loyalty, and customer service and customer satisfaction have significant influence amounted to 15,2%. Thus, this study showed that customer service and customer satisfaction have a significant effect on customer loyalty in 7-eleven Buaran Jakarta.

  7. Eleven rules for a more successful clinical psychology.

    Science.gov (United States)

    Hayes, Steven C

    2005-09-01

    The recommendations put forth in the target article, "Twenty-First Century Graduate Education in Clinical Psychology: A Four Level Matrix Model" (C.R. Snyder & T.R. Elliott, this issue, pp. 1033-1054), should be regarded in the context of the large need to develop a more progressive and effective discipline. No amount of "brute force" education and empiricism is certain to solve the problems of the scope of our field identified by the authors. Eleven rules are offered and defended that may lead to a more practically and empirically successful field.

  8. The world in eleven dimensions a tribute to Oskar Klein

    CERN Document Server

    Duff, Michael J

    2001-01-01

    Current attempts to find a unified theory that would reconcile Einstein's General Relativity and Quantum Mechanics, and explain all known physical phenomena, invoke the Kaluza-Klein idea of extra spacetime dimensions. The best candidate is M-theory, which lives in eleven dimensions, the maximum allowed by supersymmetry of the elementary particles. We give a non-technical account. An Appendix provides an updated version of Edwin A. Abbott's 1884 satire {\\it Flatland: A Romance of Many Dimensions}. Entitled {\\it Flatland, Modulo 8}, it describes the adventures of a superstring theorist, A. Square, who inhabits a ten-dimensional world and is initially reluctant to accept the existence of an eleventh dimension.

  9. Frontal fibrosing alopecia: a review of eleven patients.

    Science.gov (United States)

    Conde Fernandes, Iolanda; Selores, Manuela; Machado, Susana

    2011-01-01

    Frontal fibrosing alopecia (FFA) is a primary lymphocytic cicatricial alopecia with a distinctive clinical pattern of progressive frontotemporal hairline recession. Our purpose was to describe the clinical and histopathological features as well as the response to treatment of eleven cases of FFA diagnosed at the Trichology Consultation, over three years. A retrospective case note review was performed of eleven adult patients with FFA. The clinical data as well the histopathologic findings and laboratory tests were accessed. The patients were treated with different drugs, depending on the stage of the disease. The age of onset of the alopecia ranged from 45 to 80 years. Ten patients (90.9%) were postmenopausal women. All patients had progressive and symmetrical alopecia localized to the frontal and temporal hairline. Seven patients (63.6%) had marked decreased to complete loss of eyebrows and in four patients axillar alopecia was also evident. Laboratory investigations were normal. Scalp biopsy specimens from the anterior hairline showed similar findings. No significant improvement was observed in the majority of cases. Differential diagnosis should take into account several other conditions. It seems there is no effective treatment proven with an appropriate level of evidence in the management of FFA.

  10. Referrals to a regional allergy clinic - an eleven year audit

    Directory of Open Access Journals (Sweden)

    Hewson Paul

    2010-12-01

    Full Text Available Abstract Background Allergy is a serious and apparently increasing public health problem yet relatively little is known about the types of allergy seen in routine tertiary practice, including their spatial distribution, co-occurrence or referral patterns. This study reviewed referrals over an eleven year period to a regional allergy clinic that had a well defined geographical boundary. For those patients confirmed as having an allergy we explored: (i differences over time and by demographics, (ii types of allergy, (iii co-occurrence, and (iv spatial distributions. Methods Data were extracted from consultant letters to GPs, from September 1998 to September 2009, for patients confirmed as having an allergy. Other data included referral statistics and population data by postcode. Simple descriptive analysis was used to describe types of allergy. We calculated 11 year standardised morbidity ratios for postcode districts and checked for spatial clustering. We present maps showing 11 year rates by postcode, and 'difference' maps which try to separate referral effect from possible environmental effect. Results Of 5778 referrals, 961 patients were diagnosed with an allergy. These were referred by a total of 672 different GPs. There were marked differences in referral patterns between GP practices and also individual GPs. The mean age of patients was 35 and there were considerably more females (65% than males. Airborne allergies were the most frequent (623, and there were very high rates of co-occurrence of pollen, house dust mite, and animal hair allergies. Less than half (410 patients had a food allergy, with nuts, fruit, and seafood being the most common allergens. Fifteen percent (142 had both a food and a non-food allergy. Certain food allergies were more likely to co-occur, for example, patients allergic to dairy products were more likely to be allergic to egg. There were age differences by types of allergy; people referred with food allergies were

  11. On eleven-dimensional supergravity and Chern-Simons theory

    Energy Technology Data Exchange (ETDEWEB)

    Izaurieta, Fernando, E-mail: fizaurie@ucsc.cl [Departamento de Matematica y Fisica Aplicadas, Universidad Catolica de la Santisima Concepcion, Alonso de Ribera 2850, 4090541 Concepcion (Chile); Instituto de Matematicas, Universidad Nacional Autonoma de Mexico, Av. Insurgentes Sur s/n, D.F. (Mexico); Departament de Fisica Teorica, Universitat de Valencia, C/ Dr. Moliner 50, 46100 Burjassot, Valencia (Spain); Rodriguez, Eduardo, E-mail: edurodriguez@ucsc.cl [Departamento de Matematica y Fisica Aplicadas, Universidad Catolica de la Santisima Concepcion, Alonso de Ribera 2850, 4090541 Concepcion (Chile)

    2012-02-11

    We probe in some depth into the structure of eleven-dimensional, osp(32|1)-based Chern-Simons supergravity, as put forward by Troncoso and Zanelli (TZ) in 1997. We find that the TZ Lagrangian may be cast as a polynomial in 1/l, where l is a length, and compute explicitly the first three dominant terms. The term proportional to 1/l{sup 9} turns out to be essentially the Lagrangian of the standard 1978 supergravity theory of Cremmer, Julia and Scherk, thus establishing a previously unknown relation between the two theories. The computation is nontrivial because, when written in a sufficiently explicit way, the TZ Lagrangian has roughly one thousand non-explicitly Lorentz-covariant terms. Specially designed algebraic techniques are used to accomplish the results.

  12. Eleven years that changed the face of particle physics

    CERN Multimedia

    2000-01-01

    Director General Luciano Maiani opens the proceedings at the LEP Celebration. Members of government from around the world gathered at CERN on Monday 9 October to celebrate the achievements of the Large Electron Positron collider (LEP), the Laboratory’s flagship particle accelerator. Over the eleven years of its operational lifetime, LEP has not only added greatly to mankind’s pool of knowledge about the Universe, but has also changed the way that particle physics research is done, and proved to be a valuable training ground for young professionals in many walks of life. The celebration took place in building 180 and the audience of politicians and scientists listened to speeches from:   Prof. Luciano Maiani CERN’s Director-General Prof. Martinus Veltman Nobel Prize Laureat 1999 M. Adolf Ogi President of the Swiss Confederation Switzerland M. Roger-Gérard Schwartzenberg Minister of Research  France Mme Edelgard Bulmahn Minister of Education and R...

  13. Preliminary evaluation of alternative forms for immobilization of Savannah River Plant high-level waste. [Eleven alternative solid forms

    Energy Technology Data Exchange (ETDEWEB)

    Stone, J.A.; Goforth, S.T. Jr.; Smith, P.K.

    1979-12-01

    An evaluation of available information on eleven alternative solid forms for immobilization of SRP high-level waste has been completed. Based on the assessment of both product and process characteristics, four forms were selected for more detailed evaluation: (1) borosilicate glass made in the reference process, (2) a high-silica glass made from a porous glass matrix, (3) crystalline ceramics such as supercalcine or SYNROC, and (4) ceramics coated with an impervious barrier. The assessment includes a discussion of product and process characteristics for each of the eleven forms, a cross comparison of these characteristics for the forms, and the bases for selecting the most promising forms for further study.

  14. Renewable energy clusters recurring barriers to cluster development in eleven countries

    CERN Document Server

    Jaegersberg, Gudrun

    2017-01-01

    Taking eleven countries in Europe, Canada, South Africa, America, Latin America and Australia, this book discusses recurring barriers to cluster development in the renewable energy sector. The authors look at the real-world dynamics and tensions between stakeholders on the ground, with a particular focus on the relationships between SMEs and other actors. This trans-regional study is unique in its scale and scope, drawing on a decade of field research to show how by learning from the successes and failures of other clusters, costs and risk can be reduced. The book fills a significant gap in the literature for policymakers, managers and economic developers in a key market.

  15. Emerging and Disruptive Technologies for Education: An Analysis of Planning, Implementation, and Diffusion in Florida's Eleven State University System Institutions

    Science.gov (United States)

    Bradford, Deborah J.

    2010-01-01

    The purpose of the study was to understand and appreciate the methodologies and procedures used in determining the extent to which an information technology (IT) organization within the eleven member State University Systems (SUS) of Florida planned, implemented, and diffused emerging educational technologies. Key findings found how critical it…

  16. A Hidden Twelve-Dimensional SuperPoincare Symmetry In Eleven Dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Bars, Itzhak; Deliduman, Cemsinan; Pasqua, Andrea; Zumino, Bruno

    2003-12-13

    First, we review a result in our previous paper, of how a ten-dimensional superparticle, taken off-shell, has a hidden eleven-dimensional superPoincare symmetry. Then, we show that the physical sector is defined by three first-class constraints which preserve the full eleven-dimensional symmetry. Applying the same concepts to the eleven dimensional superparticle, taken off-shell, we discover a hidden twelve dimensional superPoincare symmetry that governs the theory.

  17. Hidden twelve-dimensional super Poincaré symmetry in eleven dimensions

    CERN Document Server

    Bars, Itzhak; Pasqua, A; Zumino, B; Bars, Itzhak; Deliduman, Cemsinan; Pasqua, Andrea; Zumino, Bruno

    2004-01-01

    First, we review a result in our previous paper, of how a ten-dimensional superparticle, taken off-shell, has a hidden eleven-dimensional superPoincare symmetry. Then, we show that the physical sector is defined by three first-class constraints which preserve the full eleven-dimensional symmetry. Applying the same concepts to the eleven dimensional superparticle, taken off-shell, we discover a hidden twelve dimensional superPoincare symmetry that governs the theory.

  18. The Knights’ Eleven Oars: In Praise of Phormio? (Ar. Eq. 546-7)

    DEFF Research Database (Denmark)

    Lech, Marcel Lysgaard

    2009-01-01

    The curious “eleven oars” of the chorus of Knights in Aristophanes’ eponymous play recall the victory of Phormio and his eleven triremes in the gulf of Naupactus in 429 B.C., and echo a lost victory ode performed at the celebration of this victory....

  19. Comparison of early-, late-, and non-participants in a school-based asthma management program for urban high school students

    Directory of Open Access Journals (Sweden)

    Alexander Gwen

    2011-06-01

    Full Text Available Abstract Background To assess bias and generalizability of results in randomized controlled trials (RCT, investigators compare participants to non-participants or early- to late-participants. Comparisons can also inform the recruitment approach, especially when working with challenging populations, such as urban adolescents. In this paper, we describe characteristics by participant status of urban teens eligible to participate in a RCT of a school-based, web-based asthma management program. Methods The denominator for this analysis was all students found to be eligible to participate in the RCT. Data were analyzed for participants and non-participants of the RCT, as well as for students that enrolled during the initially scheduled recruitment period (early-participants and persons that delayed enrollment until the following fall when recruitment was re-opened to increase sample size (late-participants. Full Time Equivalents (FTEs of staff associated with recruitment were estimated. Results Of 1668 teens eligible for the RCT, 386 enrolled early, and 36 enrolled late, leaving 1246 non-participants. Participants were younger (p Conclusions Recruitment messages attracted youth with moderate-to-severe asthma, but extending enrollment was costly, resulting in potentially less motivated, and certainly less compliant, participants. Investigators must balance internal versus external validity in the decision to extend recruitment. Gains in sample size and external validity may be offset by the cost of additional staff time and the threat to internal validity caused by lower participant follow-up. Trial Registration ClinicalTrials.gov: NCT00201058

  20. 中国股票市场非参与之谜分析%Analysis of the Non-Participation Puzzle of China's Stock Market

    Institute of Scientific and Technical Information of China (English)

    黄毓慧

    2014-01-01

    用微观调研数据分析中国股票市场非参与之谜,验证国外文献对该问题的解释:资金参与成本、认知水平,并进一步探索受教育程度、信息对认知水平的影响。实证分析从参与决策、参与深度两个层次递进展开,首先采用2SPLS克服认知水平和股市参与之间的内生性,证实了股市参与和认知之间存在双向因果关系,其次采用Tobit模型研究股票市场的参与深度。研究表明:中国股票市场参与受财富、教育、认知、信息等因素的影响,现阶段认知和信息的影响程度大于财富的影响程度,是影响中国股票市场参与的主要因素。结论凸显了投资者教育的重要性和紧迫性。%The paper analyzes the non-participation puzzle of China's stock market with mi-croscopic investigation data to prove the explanation in foreign literatures about the problem,such as capital participation cost and cognition level. Further studies are made on the education back-ground,and the influence of information on cognition level. Empirical study is made from two lev-els. Firstly,2SPLS is used to overcome the endogenous relationship between cognition level and stock market participation,which proves that there is a mutual cause-effect relationship between the two factors. Secondly,Tobit model is used to study the participation width of the stock market. Research shows that China's stock market is influenced by factors such as wealth,education,cog-nition and information. At present,the impacts of cognition and information are larger than that of the wealth,which are the main factors influencing China's stock market participation. Therefore, the education of investors becomes more important and urgent.

  1. ANALYSIS OF GENETIC PARAMETERS FOR BEAN PHYSICAL QUALITY CHARACTERS AND CLUSTERIZATIONS OF ELEVEN GENOTYPES OF ROBUSTA COFFEE (Coffea canephora

    Directory of Open Access Journals (Sweden)

    Rubiyo Rubiyo

    2013-10-01

    Full Text Available The genetic parameters of coffee related to their bean physical quality characters are important for breeder to improve the  bean quality. Eleven genotypes of robusta coffee were identified and their genetic relationship to the bean physical quality were characterized. The research was conducted at coffee plantation of the Association of Indonesian Coffee Exporters in West Lampung, altitude of 800 m above sea level, Latosol type of soil, and A type of climate, starting from 2010 to 2012. The objectives of this study were to estimate the genotypic coefficient of variation, heritability and genetic advance of the bean physical quality characters, and clusterization analysis of eleven genotypes of robusta coffee. A randomized complete block design with eleven treatments of coffee genotypes and three replications was used in this study. The results showed that the estimated values of genotypic coefficient of variation, heritability and genetic advance for small-size normal bean characters of robusta coffee were very high, so the genetic improvement for these characters has a high probability of success by direct selection. Clusterization of the genotypes resulted three clusters with their respective characteristics. The study implies that future breeding program especially for hybridization should be conducted between genotypes arising from different clusters to obtain the possible high heterosis effects.

  2. Length-weight relationship of eleven species of marine catfishes from the northern Arabian Sea coast of Pakistan

    Science.gov (United States)

    Farooq, Noureen; Qamar, Nazia; Rashid, Shahnaz; Panhwar, Sher Khan

    2016-10-01

    This study records length-weight relationships (LWRs) for eleven commercially important marine catfish species of the family Ariidae (sea catfishes) and Plotosidae (eel catfishes) from the northern Arabian Sea coast of Pakistan. The specimens were sampled from December 2014 to November 2015, using bottom trawls with various mesh sizes by commercial vessels. The species were Nemapteryx caelatus, Sciades sona, Arius gagora, Batrachocephalus mino, Netuma thalassina, N. bilineata, Osteogeneiosus militaris, Plicofollis dussumieri, P. tenuispinis, Plotosus limbatus, and P. lineatus. Of the eleven species, two species A. gagora and N. bilineata were recorded for the first time and LWRs for four species A. gagora, N. bilineata, S. sona, and B. mino still have no data in the FishBase database. In addition, new maximum length for each of the three species N. bilineata, O. militaris and B. mino was also found.

  3. A Multimodal Discourse Analysis of Tmall's Double Eleven Advertisement

    Science.gov (United States)

    Hu, Chunyu; Luo, Mengxi

    2016-01-01

    From the 1990s, the multimodal turn in discourse studies makes multimodal discourse analysis a popular topic in linguistics and communication studies. An important approach to applying Systemic Functional Linguistics to non-verbal modes is Visual Grammar initially proposed by Kress and van Leeuwen (1996). Considering that commercial advertisement…

  4. Planned, Motivated and Habitual Hygiene Behaviour: An Eleven Country Review

    Science.gov (United States)

    Curtis, Valerie A.; Danquah, Lisa O.; Aunger, Robert V.

    2009-01-01

    Handwashing with soap (HWWS) may be one of the most cost-effective means of preventing infection in developing countries. However, HWWS is rare in these settings. We reviewed the results of formative research studies from 11 countries so as to understand the planned, motivated and habitual factors involved in HWWS. On average, only 17% of child…

  5. Comparative drought response in eleven diverse alfalfa accessions

    Science.gov (United States)

    Alfalfa (Medicago sativa L.) production is often negatively affected by drought stress. This is particularly true for alfalfa that is cultivated on rangeland. Thus, the development of drought-tolerant alfalfa cultivars is of great significance. A greenhouse study was conducted to evaluate 11 alfa...

  6. Serum levels of eleven steroid hormones following motion sickness.

    Science.gov (United States)

    Stalla, G K; Doerr, H G; Bidlingmaier, F; Sippel, W G; von Restorff, W

    1985-10-01

    In order to grade motion sickness objectively, the following 11 adrenal hormones were investigated in subjects with different motion sickness susceptibility: Aldosterone, corticosterone, 11-deoxycorticosterone, progesterone, 17-OH-progesterone, 11-deoxycortisol, cortisol, cortisone, testosterone, androstendione, dehydroepiandrosterone sulfate. Motion sickness was induced by the coriolis effect on a rotary chair. Both severe kinetosis after short rotation time and mild motion sickness after 30 min of rotation occurred together with small hormonal changes. Androstendione and 11-deoxycortisol appear to be sensitive indicators of motion sickness if the rotation time is taken into consideration. A significant increase of all hormones except progesterone, cortisone, testosterone, and dehydroepiandrosterone sulfate was observed when pronounced malaise had come after a long rotation stress (24.6 min). The changes in plasma aldosterone concentration appeared to correlate with time only. The present study demonstrates that hormonal analysis can be helpful in estimating the degree of motion sickness.

  7. Heritability of eleven metabolic phenotypes in Danish and Chinese twins

    DEFF Research Database (Denmark)

    Li, Shuxia; Duan, Hongmei; Pang, Zengchang

    2013-01-01

    A twin-based comparative study on the genetic influences in metabolic endophenotypes in two populations of substantial ethnic, environmental, and cultural differences was performed. Design and Methods: Data on 11 metabolic phenotypes including anthropometric measures, blood glucose, and lipids...... levels as well as blood pressure were available from 756 pairs of Danish twins (309 monozygotic and 447 dizygotic twin pairs) with a mean age of 38 years (range: 18-67) and from 325 pairs of Chinese twins (183 monozygotic and 142 dizygotic twin pairs) with a mean age of 40.5 years (range: 18-69). Twin...... similar heritability patterns in the two samples with body weight showing only a slight difference. Higher genetic influences were estimated for fasting blood glucose level in Chinese twins, whereas the Danish twins showed more genetic regulation over most lipids phenotypes. Systolic blood pressure...

  8. Dynamic changes in an estuary over the past eleven years

    Science.gov (United States)

    Khanna, S.; Bellvert, J.; Shapiro, K.; Ustin, S.

    2015-12-01

    Extreme climatic events such as drought, 100-year floods, etc. can change the state of an ecosystem that is already in flux. The Sacramento-San Joaquin Delta in California is one of the most modified estuaries in the world. The hydrology of the Sacramento-San Joaquin Delta has been extensively altered by a network of levees, dams, and canals implemented through federal and state reclamation projects. These changes have made its ecosystem vulnerable to invasion by eliminating the competitive advantage of low-nutrient brackish-adapted native species via nutrient loading and reduced salinity which favor opportunistic species. The extreme drought in California since 2010 has likely increased shallow habitat with slow moving water, and the mild winters and lack of large storms have also favored the spread of non-native species.Six years of hyperspectral data of the Delta spread over a period of 11 years (HyMap data from 2004 to 2008, and AVIRIS-NG data in 2014) offer a unique opportunity to study the invasive species distribution in the Delta. In 2004, two aggressive freshwater invasive species were flourishing in the Delta: the floating species, Eichhornia crassipes (water hyacinth) and the submerged species, Egeria densa (Brazilian waterweed). A third invasive floating genus Ludwigia spp. (water primrose) was just beginning to establish itself in the northwest portion of the Delta. We classified these invasive species for all six years of data. Our results show that from 2004 to 2008, floating and submerged vegetation decreased overall. Among floating species, Eichhornia crassipes was co-dominant with Hydrocotyle spp., a native floating macrophyte. From 2008 to 2014 however, the total area covered by floating macrophytes in the Delta increased many-fold from 320 to 2610 hectares. The composition of this functional group also changed. Native Hydrocotyle cover reduced drastically and Ludwigia replaced it as the co-dominant comprising a third of all floating macrophyte

  9. Last generation triazoles for imported eumycetoma in eleven consecutive adults.

    Science.gov (United States)

    Crabol, Yoann; Poiree, Sylvain; Bougnoux, Marie-Elisabeth; Maunoury, Christophe; Barete, Stéphane; Zeller, Valérie; Arvieux, Cédric; Pineau, Samuel; Amazzough, Karima; Lecuit, Marc; Lanternier, Fanny; Lortholary, Olivier

    2014-10-01

    Optimal management of eumycetoma, a severely debilitating chronic progressive fungal infection of skin, disseminating to bone and viscera, remains challenging. Especially, optimal antifungal treatment and duration are ill defined. We conducted a monocentric retrospective study of 11 imported cases of eumycetoma treated by voriconazole or posaconazole for at least 6 months. Response to treatment was assessed through evolution of clinical and magnetic resonance imaging (MRI). (1→3) ß-D-glucan (BG) and positron emission tomography using [18F] fluorodeoxyglucose (PET/CT) results were also assessed. Identified species were Fusarium solani complex (n = 3); Madurella mycetomatis, (n = 3), and Exophiala jeanselmei, (n = 1). Moreover, two coelomycetes and one phaeohyphomycetes strains without species identification were retrieved. Serum BG and PET/CT were abnormal in 7/8 and 6/6 patients tested, respectively. Patients received last generation azoles for a mean duration of 25.9±18 months. Complete response (major clinical and MRI improvement) was observed in 5/11 patients, partial response (minor MRI improvement or stable MRI findings) in 5 and failure (MRI evidence of disease progression) in one, with a 73±39 [6-132] months mean follow-up. Relapse occurred in 2 patients after treatment discontinuation. Optimal outcome was associated with fungal species, initiation of last generation triazole therapy (eumycetoma.

  10. In vitro susceptibilities of Brucella melitensis isolates to eleven antibiotics

    Directory of Open Access Journals (Sweden)

    Loukaides Feidias

    2006-10-01

    Full Text Available Abstract Background Brucellosis is an endemic disease present in many countries worldwide, but it is rare in Europe and North America. Nevertheless brucella is included in the bacteria potentially used for bioterrorism. The aim of this study was the investigation of the antibiotic susceptibility profile of brucella isolates from areas of the eastern Mediterranean where it has been endemic. Methods The susceptibilities of 74 Brucella melitensis isolates derived from clinical samples (57 and animal products (17 were tested in vitro. The strains originate from Crete (59, Cyprus (10, and Syria (5. MICs of tetracycline, rifampicin, streptomycin, gentamicin, norfloxacin, ciprofloxacin, levofloxacin, trimethoprim/sulfamethoxazole, ampicillin, amoxicillin/clavulanic acid, and erythromycin were detected by E-test method. The NCCLS criteria for slow growing bacteria were considered to interpret the results. Results All the isolates were susceptible to tetracycline, streptomycin, gentamicin, ciprofloxacin, norfloxacin, and levofloxacin. Two isolates presented reduced susceptibility to rifampicin (MIC value: 1.5 mg/l and eight to SXT (MIC values: 0.75–1.5 mg/l. Erythromycin had the highest (4 mg/l MIC90value and both norfloxacin and erythromycin the highest (1.5 mg/l MIC50 value. Conclusion Brucella isolates remain susceptible in vitro to most antibiotics used for treatment of brucellosis. The establishment of a standardized antibiotic susceptibility method for Brucella spp would be useful for resistance determination in these bacteria and possible evaluation of bioterorism risks.

  11. Last generation triazoles for imported eumycetoma in eleven consecutive adults.

    Directory of Open Access Journals (Sweden)

    Yoann Crabol

    2014-10-01

    Full Text Available Optimal management of eumycetoma, a severely debilitating chronic progressive fungal infection of skin, disseminating to bone and viscera, remains challenging. Especially, optimal antifungal treatment and duration are ill defined.We conducted a monocentric retrospective study of 11 imported cases of eumycetoma treated by voriconazole or posaconazole for at least 6 months. Response to treatment was assessed through evolution of clinical and magnetic resonance imaging (MRI. (1→3 ß-D-glucan (BG and positron emission tomography using [18F] fluorodeoxyglucose (PET/CT results were also assessed. Identified species were Fusarium solani complex (n = 3; Madurella mycetomatis, (n = 3, and Exophiala jeanselmei, (n = 1. Moreover, two coelomycetes and one phaeohyphomycetes strains without species identification were retrieved. Serum BG and PET/CT were abnormal in 7/8 and 6/6 patients tested, respectively. Patients received last generation azoles for a mean duration of 25.9±18 months. Complete response (major clinical and MRI improvement was observed in 5/11 patients, partial response (minor MRI improvement or stable MRI findings in 5 and failure (MRI evidence of disease progression in one, with a 73±39 [6-132] months mean follow-up. Relapse occurred in 2 patients after treatment discontinuation. Optimal outcome was associated with fungal species, initiation of last generation triazole therapy (<65 months since first symptoms, negative serum BG and PET/CT normalization.MRI, PET/CT and serum BG appear as promising tools to assess optimal time of antifungal treatment for eumycetoma.

  12. Esquizencafalia: relato de onze casos Schizencephaly: report of eleven cases

    Directory of Open Access Journals (Sweden)

    João Guilherme Pires do Amaral

    2001-06-01

    Full Text Available O presente estudo comparou achados de tomografia computadorizada (TC com aspectos clínicos de pacientes com esquizencefalia. Sete crianças eram meninas e quatro meninos. Seis apresentavam tetraparesia, três hemiparesia e um não tinha déficit motor. Seis eram epilépticos. Dez apresentavam atraso do desenvolvimento neuropsicomotor. De acordo com os achados encontrados na TC, sete pacientes apresentaram fendas bilaterais e quatro defeito unilateral. Oito tinham fendas de lábios abertos e quatro de lábios fechados. A anomalia associada mais comum foi a ausência de septo pelúcido (n=9, seguida por nódulos subependimários (n=4, hidrocefalia (n=2 e microcefalia (n=1. Embora a ressonância magnética seja o exame padrão-ouro para diagnosticar anomalias de migração neuronal, a TC é mais disponível e pode ser útil no diagnóstico das esquizencefalias, se os aspectos típicos forem reconhecidos.A retrospective study comparing clinical and computerized tomography (CT in 11 patients diagnosed as having schizencephaly was conducted. Seven of these patients were girls and four boys. Six of them had tetraparesis, three hemiparesis and one no motor deficits. Six had epilepsy and ten developmental delay. On CT examinations, 7 patients were found as having bilateral clefts and four unilateral defect. Eight had opened lip clefts and four had a closed lip defect. The commonest associated anomaly was an absent septum pellucidum (n=9, followed by subependymal nodules (n=4, hydrocephalus (n=2 and microcephaly (n=1. Despite magnetic resonance image is the gold-standard to diagnose neuronal migration anomalies, CT can be useful in showing typical aspects of schizencephaly.

  13. Viable Compositional Analysis of an Eleven Species Oral Polymicrobial Biofilm

    Science.gov (United States)

    Sherry, Leighann; Lappin, Gillian; O'Donnell, Lindsay E.; Millhouse, Emma; Millington, Owain R.; Bradshaw, David J.; Axe, Alyson S.; Williams, Craig; Nile, Christopher J.; Ramage, Gordon

    2016-01-01

    Purpose: Polymicrobial biofilms are abundant in clinical disease, particularly within the oral cavity. Creating complex biofilm models that recapitulate the polymicrobiality of oral disease are important in the development of new chemotherapeutic agents. In order to do this accurately we require the ability to undertake compositional analysis, in addition to determine individual cell viability, which is difficult using conventional microbiology. The aim of this study was to develop a defined multispecies denture biofilm model in vitro, and to assess viable compositional analysis following defined oral hygiene regimens. Methods: An in vitro multispecies denture biofilm containing various oral commensal and pathogenic bacteria and yeast was created on poly (methyl methacrylate) (PMMA). Denture hygiene regimens tested against the biofilm model included brushing only, denture cleansing only and combinational brushing and denture cleansing. Biofilm composition and viability were assessed by culture (CFU) and molecular (qPCR) methodologies. Scanning electron microscopy and confocal laser scanning microscopy were also employed to visualize changes in denture biofilms following treatment. Results: Combinational treatment of brushing and denture cleansing had the greatest impact on multispecies denture biofilms, reducing the number of live cells by more than 2 logs, and altering the overall composition in favor of streptococci. This was even more evident during the sequential testing, whereby daily sequential treatment reduced the total and live number of bacteria and yeast more than those treated intermittently. Bacteria and yeast remaining following treatment tended to aggregate in the pores of the PMMA, proving more difficult to fully eradicate the biofilm. Conclusions: Overall, we are the first to develop a method to enable viable compositional analysis of an 11 species denture biofilm following chemotherapeutic challenge. We were able to demonstrate viable cell

  14. Tibial plateau levelling osteotomy in eleven cats with cranial cruciate ligament rupture.

    Science.gov (United States)

    Mindner, Julia K; Bielecki, Malgorzata J; Scharvogel, Stefan; Meiler, Diane

    2016-11-23

    To report the surgical procedure, intra- and postoperative complications, and short-term follow-up of tibial plateau levelling osteotomy (TPLO) in feline patients with cranial cruciate ligament (CrCL) rupture using a 2.0 or 2.4 mm Synthes(®) TPLO plate. Prospective study. Eleven cats with a CrCL rupture were included in the study. Inspection of intra-articular structures was carried out via arthroscopy or arthrotomy. Each patient was re-examined one and 10 days after surgery. Orthopaedic examination and follow-up radiographs were obtained four to 12 weeks postoperatively. Two meniscopathies and one partial CrCL rupture were detected. Minor intra-operative complications occurred in five cats (suboptimal positioning of the plate [n = 3], proximal fibular fracture [n = 1], a visible osteotomy gap [n = 1]). Postoperatively, minor complications were detected in three cats (mild patellar desmitis [n = 2], superficial wound infection [n = 1]). No additional surgical reintervention, graded as major complication, was necessary. Four to eight weeks postoperatively, all cats showed no to mild intermittent lameness. Complete bone union was apparent within four to 12 weeks. Owners reported a high level of comfort and mobility during the last follow-up. The preliminary results of this study support the use of TPLO in cats, but larger case numbers are needed to evaluate its practicability, as well as long-term outcome (>1 year), especially evaluating the development and the clinical relevance of osteoarthritis.

  15. Non-participation in screening

    DEFF Research Database (Denmark)

    Dugué, Pierre-Antoine; Lynge, Elsebeth; Bjerregaard, Beth;

    2012-01-01

    To determine the impact of comprehensiveness of cytology registration on the proportion of cervical cancer patients without a recent screening history.......To determine the impact of comprehensiveness of cytology registration on the proportion of cervical cancer patients without a recent screening history....

  16. Simulation of Few Bifurcation Phase Diagrams of Belousov-Zhabotinsky Reaction with Eleven Variable Chaotic Model in CSTR

    Directory of Open Access Journals (Sweden)

    B. Swathi

    2009-01-01

    Full Text Available Simulation of the Gyorgyi, Rempe and Field eleven variable chaotic model in CSTR [Continuously Stirred Tank Reactor] is performed with respect to the concentrations of malonic acid and [Ce(III]. These simulation studies show steady state, periodic and non-periodic regions. These studies have been presented as two variable bifurcation phase diagrams. We also have observed the bursting phenomenon under different set of constraints. We have given much importance on computer simulation work but not included the experimental methods in this paper.

  17. Analysis on Scientific Research Strength of Academic Libraries in Jiangsu Province:Based on the Study of Eleven "211 Project" Universities' Libraries in Jiangsu%江苏省高校图书馆科研实力分析——以江苏省11所"211高校"图书馆为例

    Institute of Scientific and Technical Information of China (English)

    傅余洋子; 邓三鸿; 陆宇飞

    2015-01-01

    Taking the academic libraries of eleven "211 project" universities in Jiangsu Province as statistical source in "China Academic Journal Network Publishing Database" of CNKI, this paper carries on a statistics to the total number of research articles published in recent twenty years, and analyzes them with the method of bibliometrics from several aspects such as publishing date, journal distribution, fund, citation frequency, h-index, highly quoted literature and highly cited author, in order to reflect the developmental status and scientific research strength of academic libraries in Jiangsu Province.%论文以CNKI下的《中国学术期刊网络出版总库》为数据源,从文献计量的角度统计了江苏省11所"211高校"的图书馆在近20年的发文情况,并从年份分布、期刊、基金、被引频次、h指数、高频被引论文、高被引作者等多个角度进行了分析,揭示了以此为代表的江苏省高校图书馆的学术研究现状与科研实力.

  18. Six sigma: program characteristics in eleven companies located in the metropolitan region of Porto Alegre

    Directory of Open Access Journals (Sweden)

    Jaqueline Terezinha Martins Correa Rodrigues

    2012-01-01

    Full Text Available Six Sigma combines managerial factors with statistical tools and is deployed in many enterprises today. Rio Grande do Sul is a Brazilian state that has a great industrialization, especially in the metropolitan area of Porto Alegre. Some of these industries have deployed the Six Sigma program. The aim of this paper is to present characteristics of the Six Sigma program in companies located in this region, through an exploratory study. A literature review subsidized the development of the questionnaire. Eleven companies participated of research in July and August 2008. It used statistical tools and qualitative analysis to analyze the results. Most of the companies that participated is classified as large and uses the DMAIC method to implement Six Sigma. The principal cause of program implementation was process improvement. In only one company the Six Sigma is implemented in all sectors, including administrative areas. Another result is the lack of clearly criteria for defining the career of Belts and the discrepancy of academic formation of these specialists.

  19. Selective harmonic elimination strategy in eleven level inverter for PV system with unbalanced DC sources

    Science.gov (United States)

    Ghoudelbourk, Sihem.; Dib, D.; Meghni, B.; Zouli, M.

    2017-02-01

    The paper deals with the multilevel converters control strategy for photovoltaic system integrated in distribution grids. The objective of the proposed work is to design multilevel inverters for solar energy applications so as to reduce the Total Harmonic Distortion (THD) and to improve the power quality. The multilevel inverter power structure plays a vital role in every aspect of the power system. It is easier to produce a high-power, high-voltage inverter with the multilevel structure. The topologies of multilevel inverter have several advantages such as high output voltage, lower total harmonic distortion (THD) and reduction of voltage ratings of the power semiconductor switching devices. The proposed control strategy ensures an implementation of selective harmonic elimination (SHE) modulation for eleven levels. SHE is a very important and efficient strategy of eliminating selected harmonics by judicious selection of the firing angles of the inverter. Harmonics elimination technique eliminates the need of the expensive low pass filters in the system. Previous research considered that constant and equal DC sources with invariant behavior; however, this research extends earlier work to include variant DC sources, which are typical of lead-acid batteries when used in system PV. This Study also investigates methods to minimize the total harmonic distortion of the synthesized multilevel waveform and to help balance the battery voltage. The harmonic elimination method was used to eliminate selected lower dominant harmonics resulting from the inverter switching action.

  20. Complete mitochondrial genomes of eleven extinct or possibly extinct bird species.

    Science.gov (United States)

    Anmarkrud, Jarl A; Lifjeld, Jan T

    2017-03-01

    Natural history museum collections represent a vast source of ancient and historical DNA samples from extinct taxa that can be utilized by high-throughput sequencing tools to reveal novel genetic and phylogenetic information about them. Here, we report on the successful sequencing of complete mitochondrial genome sequences (mitogenomes) from eleven extinct bird species, using de novo assembly of short sequences derived from toepad samples of degraded DNA from museum specimens. For two species (the Passenger Pigeon Ectopistes migratorius and the South Island Piopio Turnagra capensis), whole mitogenomes were already available from recent studies, whereas for five others (the Great Auk Pinguinis impennis, the Imperial Woodpecker Campehilus imperialis, the Huia Heteralocha acutirostris, the Kauai Oo Moho braccathus and the South Island Kokako Callaeas cinereus), there were partial mitochondrial sequences available for comparison. For all seven species, we found sequence similarities of >98%. For the remaining four species (the Kamao Myadestes myadestinus, the Paradise Parrot Psephotellus pulcherrimus, the Ou Psittirostra psittacea and the Lesser Akialoa Akialoa obscura), there was no sequence information available for comparison, so we conducted blast searches and phylogenetic analyses to determine their phylogenetic positions and identify their closest extant relatives. These mitogenomes will be valuable for future analyses of avian phylogenetics and illustrate the importance of museum collections as repositories for genomics resources. © 2016 John Wiley & Sons Ltd.

  1. Cellular and molecular portrait of eleven human glioblastoma cell lines under photon and carbon ion irradiation.

    Science.gov (United States)

    Ferrandon, S; Magné, N; Battiston-Montagne, P; Hau-Desbat, N-H; Diaz, O; Beuve, M; Constanzo, J; Chargari, C; Poncet, D; Chautard, E; Ardail, D; Alphonse, G; Rodriguez-Lafrasse, C

    2015-04-28

    This study aimed to examine the cellular and molecular long-term responses of glioblastomas to radiotherapy and hadrontherapy in order to better understand the biological effects of carbon beams in cancer treatment. Eleven human glioblastoma cell lines, displaying gradual radiosensitivity, were irradiated with photons or carbon ions. Independently of p53 or O(6)-methylguanine-DNA methyltransferase(1) status, all cell lines responded to irradiation by a G2/M phase arrest followed by the appearance of mitotic catastrophe, which was concluded by a ceramide-dependent-apoptotic cell death. Statistical analysis demonstrated that: (i) the SF2(2) and the D10(3) values for photon are correlated with that obtained in response to carbon ions; (ii) regardless of the p53, MGMT status, and radiosensitivity, the release of ceramide is associated with the induction of late apoptosis; and (iii) the appearance of polyploid cells after photon irradiation could predict the Relative Biological Efficiency(4) to carbon ions. This large collection of data should increase our knowledge in glioblastoma radiobiology in order to better understand, and to later individualize, appropriate radiotherapy treatment for patients who are good candidates.

  2. Cervical neuroblastoma in eleven infants--a tumor with favorable prognosis. Clinical and radiologic (US, CT, MRI) findings.

    Science.gov (United States)

    Abramson, S J; Berdon, W E; Ruzal-Shapiro, C; Stolar, C; Garvin, J

    1993-01-01

    Cervical neuroblastoma, a disease primarily of infants, has a favorable prognosis. Eleven patients are reported. Clinical presentations (other than mass) included stridor and swallowing problems. Masses when felt were commonly mistaken for infectious adenitis. Imaging studies (US, CT, MRI) showed solid masses with vascular displacement and narrowing; intraspinal extension was absent though extension into the adjacent sites of mediastinum and skull occurred. Horner syndrome was seen in five patients with accompanying heterochromia iridis in one. Five tumors had calcification. A high index of suspicion will lead to biopsy and less delay in diagnosis once a mass is felt or imaged.

  3. Consumption of fruits and vegetables among adolescents: a multi-national comparison of eleven countries in the Eastern Mediterranean Region.

    Science.gov (United States)

    Al Ani, M F; Al Subhi, L K; Bose, S

    2016-03-28

    Regional cross-country profile of fruit and vegetable (F&V) consumption is lacking in the Eastern Mediterranean Region (EMR). This study examines the prevalence and differences of consuming F&V ≥5 times/d among adolescents in eleven EMR countries, and also describes differences in the proportions of taking F&V ≥5 times/d by sex, age and BMI. The study included 26 328 school adolescents (13-15 years) with complete data on consumption of F&V, age, sex, weight and height taken from the Global School-based Student Health Survey conducted in the EMR between 2005 and 2009. Overall, only 19·4 % of adolescents reported consuming F&V ≥5 times/d. The highest prevalence was reported in Djibouti (40·4 %) and the lowest was reported in Pakistan (10·0 %). Statistically significant differences in prevalence were observed across countries (P<0·05). With the exception of Oman, Libya and Djibouti, significantly more males than females ate F&V ≥5 times/d. Proportion of students consuming F&V ≥5 times/d also varied significantly in all counties based on BMI (P<0·0001), with students within normal BMI having the highest frequency. A negative trend was observed between age and the prevalence of taking F&V ≥5 times/d in most of the eleven EMR countries but Jordan, Djibouti and Morocco. The prevalence of adequate intake of F&V was low in the eleven EMR countries. There is a need for interventions to increase the prevalence of adolescents consuming F&V ≥5 times/d. Interventions should take into consideration psychosocial, environmental and socio-environmental factors influencing F&V intake within countries.

  4. Predictive performance of eleven pharmacokinetic models for propofol infusion in children for long-duration anaesthesia

    NARCIS (Netherlands)

    Hara, M.; Masui, K.; Eleveld, D. J.; Struys, M. M. R. F.; Uchida, O.

    Background. Predictive performance of eleven published propofol pharmacokinetic models was evaluated for long-duration propofol infusion in children. Methods. Twenty-one aged three-11 yr ASA I-II patients were included. Anaesthesia was induced with propofol or sevoflurane, and maintained with

  5. Natural occurrence, biological activities and synthesis of eight-, nine-, and eleven-membered ring lactones

    Directory of Open Access Journals (Sweden)

    Helena M. C. Ferraz

    2008-01-01

    Full Text Available The natural occurrence, biological activities and synthetic approaches to natural eight-, nine-, and eleven-membered lactones is reviewed. These medium ring lactones are grouped according to ring size, and their syntheses are discussed. The structures of some natural products early identified as medium-ring lactones were revised after total synthesis.

  6. Deformations of gauged SO(8) supergravity and supergravity in eleven dimensions

    NARCIS (Netherlands)

    Wit, B. de; Nicolai, H.

    2013-01-01

    Motivated by the fact that there exists a continuous one-parameter family of gauged SO(8) supergravities, possible eleven-dimensional origins of this phenomenon are explored. Taking the original proof of the consistency of the truncation of 11D supergravity to SO(8) gauged supergravity as a starting

  7. Brodie's abscess in the first decade of life. Report of eleven cases.

    Science.gov (United States)

    Kozlowski, K

    1980-09-01

    Eleven cases of Brodie's abscess in the first decade of life are presented. Brodie's abscess in the first decade of life usually shows the "Variant type" of X-ray appearances. The X-ray diagnosis is easy if the clinical data is known to the radiologist. The preponderance of Brodie's abscesses in the lower extremities is probably due to trauma.

  8. Comparative meta-analysis of tuberculosis contact investigation interventions in eleven high burden countries.

    Science.gov (United States)

    Blok, Lucie; Sahu, Suvanand; Creswell, Jacob; Alba, Sandra; Stevens, Robert; Bakker, Mirjam I

    2015-01-01

    Screening of household contacts of tuberculosis (TB) patients is a recommended strategy to improve early case detection. While it has been widely implemented in low prevalence countries, the most optimal protocols for contact investigation in high prevalence, low resource settings is yet to be determined. This study evaluated contact investigation interventions in eleven lower and middle income countries and reviewed the association between context or program-related factors and the yield of cases among contacts. We reviewed data from nineteen first wave TB REACH funded projects piloting innovations to improve case detection. These nineteen had fulfilled the eligibility criteria: contact investigation implementation and complete data reporting. We performed a cross-sectional analysis of the percentage yield and case notifications for each project. Implementation strategies were delineated and the association between independent variables and yield was analyzed by fitting a random effects logistic regression. Overall, the nineteen interventions screened 139,052 household contacts, showing great heterogeneity in the percentage yield of microscopy confirmed cases (SS+), ranging from 0.1% to 6.2%). Compared to the most restrictive testing criteria (at least two weeks of cough) the aOR's for lesser (any TB related symptom) and least (all contacts) restrictive testing criteria were 1.71 (95%CI 0.94-3.13) and 6.90 (95% CI 3.42-13.93) respectively. The aOR for inclusion of SS- and extra-pulmonary TB was 0.31 (95% CI 0.15-0.62) compared to restricting index cases to SS+ TB. Contact investigation contributed between <1% and 14% to all SS+ cases diagnosed in the intervention areas. This study confirms that high numbers of active TB cases can be identified through contact investigation in a variety of contexts. However, design and program implementation factors appear to influence the yield of contact investigation and its concomitant contribution to TB case detection.

  9. Worldwide food recall patterns over an eleven month period: A country perspective

    Directory of Open Access Journals (Sweden)

    Petróczi Andrea

    2008-09-01

    Full Text Available Abstract Background Following the World Health Organization Forum in November 2007, the Beijing Declaration recognized the importance of food safety along with the rights of all individuals to a safe and adequate diet. The aim of this study is to retrospectively analyze the patterns in food alert and recall by countries to identify the principal hazard generators and gatekeepers of food safety in the eleven months leading up to the Declaration. Methods The food recall data set was collected by the Laboratory of the Government Chemist (LGC, UK over the period from January to November 2007. Statistics were computed with the focus reporting patterns by the 117 countries. The complexity of the recorded interrelations was depicted as a network constructed from structural properties contained in the data. The analysed network properties included degrees, weighted degrees, modularity and k-core decomposition. Network analyses of the reports, based on 'country making report' (detector and 'country reported on' (transgressor, revealed that the network is organized around a dominant core. Results Ten countries were reported for sixty per cent of all faulty products marketed, with the top 5 countries having received between 100 to 281 reports. Further analysis of the dominant core revealed that out of the top five transgressors three made no reports (in the order China > Turkey > Iran. The top ten detectors account for three quarters of reports with three > 300 (Italy: 406, Germany: 340, United Kingdom: 322. Conclusion Of the 117 countries studied, the vast majority of food reports are made by 10 countries, with EU countries predominating. The majority of the faulty foodstuffs originate in ten countries with four major producers making no reports. This pattern is very distant from that proposed by the Beijing Declaration which urges all countries to take responsibility for the provision of safe and adequate diets for their nationals.

  10. Comparative meta-analysis of tuberculosis contact investigation interventions in eleven high burden countries.

    Directory of Open Access Journals (Sweden)

    Lucie Blok

    Full Text Available Screening of household contacts of tuberculosis (TB patients is a recommended strategy to improve early case detection. While it has been widely implemented in low prevalence countries, the most optimal protocols for contact investigation in high prevalence, low resource settings is yet to be determined. This study evaluated contact investigation interventions in eleven lower and middle income countries and reviewed the association between context or program-related factors and the yield of cases among contacts.We reviewed data from nineteen first wave TB REACH funded projects piloting innovations to improve case detection. These nineteen had fulfilled the eligibility criteria: contact investigation implementation and complete data reporting. We performed a cross-sectional analysis of the percentage yield and case notifications for each project. Implementation strategies were delineated and the association between independent variables and yield was analyzed by fitting a random effects logistic regression.Overall, the nineteen interventions screened 139,052 household contacts, showing great heterogeneity in the percentage yield of microscopy confirmed cases (SS+, ranging from 0.1% to 6.2%. Compared to the most restrictive testing criteria (at least two weeks of cough the aOR's for lesser (any TB related symptom and least (all contacts restrictive testing criteria were 1.71 (95%CI 0.94-3.13 and 6.90 (95% CI 3.42-13.93 respectively. The aOR for inclusion of SS- and extra-pulmonary TB was 0.31 (95% CI 0.15-0.62 compared to restricting index cases to SS+ TB. Contact investigation contributed between <1% and 14% to all SS+ cases diagnosed in the intervention areas.This study confirms that high numbers of active TB cases can be identified through contact investigation in a variety of contexts. However, design and program implementation factors appear to influence the yield of contact investigation and its concomitant contribution to TB case detection.

  11. Formation of N-nitrosamines from eleven disinfection treatments of seven different surface waters.

    Science.gov (United States)

    Zhao, Yuan-Yuan; Boyd, Jessica M; Woodbeck, Matthew; Andrews, Robert C; Qin, Feng; Hrudey, Steve E; Li, Xing-Fang

    2008-07-01

    Formation of nine N-nitrosamines has been investigated when seven different source waters representing various qualities were each treated with eleven bench-scale disinfection processes, without addition of nitrosamine precursors. These disinfection treatments included chlorine (OCl-), chloramine (NH2Cl), chlorine dioxide (ClO2), ozone (O3), ultraviolet (UV), advanced oxidation processes (AOP), and combinations. The total organic carbon (TOC) of the seven source waters ranged from 2 to 24 mg x L(-1). The disinfected water samples and the untreated source waters were analyzed for nine nitrosamines using a solid phase extraction and liquid chromatography-tandem mass spectrometry method. Prior to any treatment, N-nitrosodimethylamine (NDMA) was detected ranging from 0 to 53 ng x L(-1) in six of the seven source waters, and its concentrations increased in the disinfected water samples (0-118 ng x L(-1)). N-nitrosodiethylamine (NDEA), N-nitrosomorpholine (NMor), and N-nitrosodiphenylamine (NDPhA) were also identified in some of the disinfected water samples. NDPhA (0.2-0.6 ng x L(-1)) was formed after disinfection with OCl-, NH2Cl, O3, and MPUV/OCl-. NMEA was produced with OCl- and MPUV/OCl-, and NMor formation was associated with O3. In addition, UVtreatment alone degraded NDMA; however, UV/ OCl- and AOP/OCl- treatments produced higher amounts of NDMA compared to UV and AOP alone, respectively. These results suggest that UV degradation or AOP oxidation treatment may provide a source of NDMA precursors. This study demonstrates that environmental concentrations and mixtures of unknown nitrosamine precursors in source waters can form NDMA and other nitrosamines.

  12. [Eleven thesis on the archive of scientific research, for a new patrimonial and scientific policy].

    Science.gov (United States)

    Müller, Bertrand

    2015-12-01

    Abstracting the main content of a recent report on the bad state of the archives of scientific research, this paper puts forward eleven thesis likely to feed, in this time of numeric transition to a new documentary regime and to a new patrimonial policy. The recent numeric conditions impose to set new archival pratices, more proactive, anticipative and prospective. Archives of scientific research must be thought in a double memorial and scientific dimension, and not only as a patrimonial or historical one.

  13. Potential of eleven Eucalyptus species for the production of essential oils

    OpenAIRE

    2006-01-01

    Most Eucalyptus plantations in Brazil aim the production of paper and charcoal, but the use of the species for lumbering, construction and extraction of essential oil has increased. Eleven species of Eucalyptus were assessed in regard to their essential oil production potential, nine never used before for commercial, essential oil extraction. Assessements were compared with Eucalyptus citriodora and Eucalyptus globulus, already explored in oil production for perfume and medical purposes, aimi...

  14. DFT Predictions on Structures and Stabilities of Eleven-vertex nido-and cioso-Heteroboranes

    Institute of Scientific and Technical Information of China (English)

    LI Ping

    2009-01-01

    Based on the octadecahedron of eleven-vertex closo-borane,the eleven-vertex closo-heteroborane was suggested with nonmetallic atoms instead of the different nonequivalent boron,and the stabilities were predicted at G96PW91/6-31+G(3d,2p) level.The small heteroatoms,C,N,O,preferentially occupy vertex 2 with the absolutely lowest relative energy to form the high stabilization closo-heteroboranes.They cap four-membered rings to satisfy the geometrical demand of short B-Z bonds.The electron attractions from the vicinal boron atoms make the frameworks shrink.Differently,Si and Ge preferentially substitute for boron at vertex 1 with six tight B-Z bonds and form stabilized molecules.P,As,S,and Se tend to occupy vertex 4 and the optimized structures belong to the nido configurations,in contrast to high electronegative heteroatoms,S and Se transfer less negative charges to framework and the electropositive heteroatoms,Si and Ge transfer more negative charges to framework to form the delocalization structures.The HOMO-LUMO gaps show that most of predicted clusters possess chemical stabilities.The substitutions of heteroatoms for boron atoms in eleven-vertex closo-hcteroboranes are consistent with the topological charge stabilization rule proposed by Gimarc.

  15. Three-dimensional knee kinematics by conventional gait analysis for eleven motor tasks of daily living: typical patterns and repeatability.

    Science.gov (United States)

    Scheys, Lennart; Leardini, Alberto; Wong, Pius D; Van Camp, Laurent; Callewaert, Barbara; Bellemans, Johan; Desloovere, Kaat

    2013-04-01

    The availability of detailed knee kinematic data during various activities can facilitate clinical studies of this joint. To describe in detail normal knee joint rotations in all three anatomical planes, 25 healthy subjects (aged 22-49 years) performed eleven motor tasks, including walking, step ascent and descent, each with and without sidestep or crossover turns, chair rise, mild and deep squats, and forward lunge. Kinematic data were obtained with a conventional lower-body gait analysis protocol over three trials per task. To assess the repeatability with standard indices, a representative subset of 10 subjects underwent three repetitions of the entire motion capture session. Extracted parameters with good repeatability included maximum and minimum axial rotation during turning, local extremes of the flexion curves during gait tasks, and stride times. These specific repeatable parameters can be used for task selection or power analysis when planning future clinical studies.

  16. Lumbar total disc replacement. Seven to eleven-year follow-up.

    Science.gov (United States)

    Tropiano, Patrick; Huang, Russel C; Girardi, Federico P; Cammisa, Frank P; Marnay, Thierry

    2005-03-01

    Symptomatic lumbar degenerative disc disease is a challenging entity to treat. The results of arthrodesis may be compromised in the short term by pseudarthrosis and in the long term by pain at the iliac-crest donor site and by junctional degeneration. Total disc replacement has the potential to provide long-lasting relief to these patients. The purpose of this study was to present the clinical and radiographic results assessed seven to eleven years following a Prodisc total lumbar disc replacement. Sixty-four patients had single or multiple-level implantation of a total lumbar disc replacement between 1990 and 1993. The mean duration of follow-up was 8.7 years. Clinical results were evaluated by assessing preoperative and postoperative lumbar pain, radiculopathy, disability, and modified Stauffer-Coventry scores. Preoperative and postoperative radiographs were evaluated as well. Subgroup analysis was performed to determine if gender, an age of less than forty-five years, previous surgery, or multilevel surgery had an effect on outcome. At an average of 8.7 years postoperatively, there were significant improvements in the back-pain, radiculopathy, disability, and modified Stauffer-Coventry scores. Thirty-three of the fifty-five patients with sufficient follow-up had an excellent result, eight had a good result, and fourteen had a poor result. Neither gender nor multilevel surgery affected outcome. An age of less than forty-five years and prior lumbar surgery had small but significant negative effects on outcome. Radiographs did not demonstrate loosening, migration, or mechanical failure in any patient. Five patients had approach-related complications. The Prodisc lumbar total disc replacement appears to be effective and safe for the treatment of symptomatic degenerative disc disease. Gender and multilevel surgery did not affect the outcomes, whereas prior lumbar surgery or an age of less than forty-five years was associated with slightly worse outcomes. Longer

  17. Antioxidant-enriched leaf water extracts of Cinnamomum osmophloeum from eleven provenances and their bioactive flavonoid glycosides

    Directory of Open Access Journals (Sweden)

    Chi-Lin Wu

    2013-02-01

    Full Text Available The study was designed to investigate the antioxidant activities of water extracts of C. osmophloeum leaves from eleven provenances (CO1-CO11 and their bioactive phytochemicals. Results revealed that leaf water extracts contained antioxidant phytochemicals and showed efficacy as antioxidants. Among varied leaf water extracts, water extract of CO4 showed the highest total phenolic content (160.9 mg/g and superior free radical scavenging ability with the IC50 values of 10.3 and 16.9 μg/mL for DPPH and superoxide radical scavenging assays, respectively. It was also found to exhibit the best metal chelating ability and reducing power. According to the multiple spectral analyses, bioactive phytochemicals of leaf water extracts were flavonoid glycosides, including kaempferol-7-O-rhamnoside and kaempferol-3,7-O-dirhamnoside. Leaf water extracts of C. osmophloeum with high performance of antioxidant efficacy have great potential as a natural daily supplement.

  18. Measurement equivalence of the CES-D 8 depression-scale among the ageing population in eleven European countries.

    Science.gov (United States)

    Missinne, Sarah; Vandeviver, Christophe; Van de Velde, Sarah; Bracke, Piet

    2014-07-01

    Depression is one of the most prevalent mental disorders in later life. However, despite considerable research attention, great confusion remains regarding the association between ageing and depression. There is doubt as to whether a depression scale performs identically for different age groups and countries. Although measurement equivalence is a crucial prerequisite for valid comparisons across age groups and countries, it has not been established for the eight-item version of the Centre for Epidemiological Studies Depression Scale (CES-D8). Using multi-group confirmatory factor analysis, we assess configural, metric, and scalar measurement equivalence across two age groups (50-64 years of age and 65 or older) in eleven European countries, employing data from the Survey of Health, Ageing, and Retirement (SHARE). Results indicate that the construct of depression is comparable across age and country groups, allowing the substantive interpretation of correlates and mean levels of depressive symptoms.

  19. Are participants in markets for water rights more efficient in the use of water than non-participants? A case study for Limarí Valley (Chile).

    Science.gov (United States)

    Molinos-Senante, María; Donoso, Guillermo; Sala-Garrido, Ramon

    2016-06-01

    The need to increase water productivity in agriculture has been stressed as one of the most important factors to achieve greater agricultural productivity and sustainability. The main aim of this paper is to investigate whether there are differences in water use efficiency (WUE) between farmers who participate in water markets and farmers who do not participate in them. Moreover, the use of a non-radial data envelopment analysis model allows to compute global efficiency (GE), WUE as well the efficiency in the use of other inputs such as fertilizers, pesticides, energy, and labor. In a second stage, external factors that may affect GE and WUE are explored. The empirical application focuses on a sample of farmers located in Limarí Valley (Chile) where regulated permanent water rights (WR) markets for surface water have a long tradition. Results illustrate that WR sellers are the most efficient in the use of water while non-traders are the farmers that present the lowest WUE. From a policy perspective, significant conclusions are drawn from the assessment of agricultural water productivity in the framework of water markets.

  20. Towards a universal product ion mass spectral library - reproducibility of product ion spectra across eleven different mass spectrometers.

    Science.gov (United States)

    Hopley, Chris; Bristow, Tony; Lubben, Anneke; Simpson, Alec; Bull, Elaine; Klagkou, Katerina; Herniman, Julie; Langley, John

    2008-06-01

    Product ion spectra produced by collision-induced dissociation (CID) in tandem mass spectrometry experiments can differ markedly between instruments. There have been a number of attempts to standardise the production of product ion spectra; however, a consensus on the most appropriate approach to the reproducible production of spectra has yet to be reached. We have previously reported the comparison of product ion spectra on a number of different types of instruments - a triple quadrupole, two ion traps and a Fourier transform ion cyclotron resonance mass spectrometer (Bristow AWT, Webb KS, Lubben AT, Halket JM. Rapid Commun. Mass Spectrom. 2004; 18: 1). The study showed that a high degree of reproducibility was achievable. The goal of this study was to improve the comparability and reproducibility of CID product ion mass spectra produced in different laboratories and using different instruments. This was carried out experimentally by defining a spectral calibration point on each mass spectrometer for product ion formation. The long-term goal is the development of a universal (instrument independent) product ion mass spectral library for the identification of unknowns. The spectra of 48 compounds have been recorded on eleven mass spectrometers: six ion traps, two triple quadrupoles, a hybrid triple quadrupole, and two quadrupole time-of-flight instruments. Initially, 4371 spectral comparisons were carried out using the data from eleven instruments and the degree of reproducibility was evaluated. A blind trial has also been carried out to assess the reproducibility of spectra obtained during LC/MS/MS. The results suggest a degree of reproducibility across all instrument types using the tuning point technique. The reproducibility of the product ion spectra is increased when comparing the tandem in time type instruments and the tandem in space instruments as two separate groups. This may allow the production of a more limited, yet useful, screening library for LC

  1. Comparison of eleven methods for genomic DNA extraction suitable for large-scale whole-genome genotyping and long-term DNA banking using blood samples

    OpenAIRE

    Androniki Psifidi; Dovas, Chrysostomos I.; Georgios Bramis; Thomai Lazou; Russel, Claire L; Georgios Arsenos; Georgios Banos

    2015-01-01

    Over the recent years, next generation sequencing and microarray technologies have revolutionized scientific research with their applications to high-throughput analysis of biological systems. Isolation of high quantities of pure, intact, double stranded, highly concentrated, not contaminated genomic DNA is prerequisite for successful and reliable large scale genotyping analysis. High quantities of pure DNA are also required for the creation of DNA-banks. In the present study, eleven differen...

  2. Photogrammetry research for FAST eleven-meter reflector panel surface shape measurement

    Science.gov (United States)

    Zhou, Rongwei; Zhu, Lichun; Li, Weimin; Hu, Jingwen; Zhai, Xuebing

    2010-10-01

    In order to design and manufacture the Five-hundred-meter Aperture Spherical Radio Telescope (FAST) active reflector measuring equipment, measurement on each reflector panel surface shape was presented, static measurement of the whole neutral spherical network of nodes was performed, real-time dynamic measurement at the cable network dynamic deformation was undertaken. In the implementation process of the FAST, reflector panel surface shape detection was completed before eleven-meter reflector panel installation. Binocular vision system was constructed based on the method of binocular stereo vision in machine vision, eleven-meter reflector panel surface shape was measured with photogrammetry method. Cameras were calibrated with the feature points. Under the linearity camera model, the lighting spot array was used as calibration standard pattern, and the intrinsic and extrinsic parameters were acquired. The images were collected for digital image processing and analyzing with two cameras, feature points were extracted with the detection algorithm of characteristic points, and those characteristic points were matched based on epipolar constraint method. Three-dimensional reconstruction coordinates of feature points were analyzed and reflective panel surface shape structure was established by curve and surface fitting method. The error of reflector panel surface shape was calculated to realize automatic measurement on reflector panel surface shape. The results show that unit reflector panel surface inspection accuracy was 2.30mm, within the standard deviation error of 5.00mm. Compared with the requirement of reflector panel machining precision, photogrammetry has fine precision and operation feasibility on eleven-meter reflector panel surface shape measurement for FAST.

  3. "Vi har musikk i skolen for å bli bedre til å synge!" Elevens egen stemme om sangaktiviteten i skolens musikkopplæring

    Directory of Open Access Journals (Sweden)

    Odd Magne Bøe

    2010-12-01

    Full Text Available Artikkelen fokuserer på elevenes egne opplevelser omkring sangaktiviteter i skolens musikkopplæring. Sang i skolen drøftes i lys av de rammene vi finner i ”Læreplanverket for Kunnskapsløftet” (LK06. Et sentralt spørsmål vil være om elever i ulike aldre forteller om endring av musikkaktiviteter i takt med et utvidet register i faget. Jeg vil i tillegg diskutere i hvilken grad elevens stemme vil kunne bringe fram ny viten om musikkfaget. Artikkelen er tredelt. Først beskrives målet med studien og begrunnelser for valg av metode. Deretter presenteres resultater fra empirien basert på kvalitative data fra elevintervjuer. I den tredje delen tar drøftingen utgangspunkt i de funn jeg gjorde i min studie.

  4. Simultaneous determination of eleven characteristic lignans in Schisandra chinensis by high-performance liquid chromatography

    Directory of Open Access Journals (Sweden)

    Junyang Hu

    2013-01-01

    Full Text Available Background: Schisandra chinensis, one of the well-known traditional Chinese herbal medicines, is derived from the dry ripe fruits of Schisandra chinensis (Turcz. Baill. according to the 9th China Pharmacopeia. Lignans are the main components isolated from extracts of S. chinensis and their content varies depending on where S. chinensis was collected. We have established a qualitative and quantitative method based on the bioactive lignans for control of the quality of S. chinensis from different sources. Materials and Methods: To develop a high-performance liquid chromatography method, an Elite ODS C18 column (250 mm Χ 4.6 mm, 5μm at a column temperature of 30°C and flow rate of 1.0ml/min using acetonitrile (A and water (B as the mobile phase with a linear gradient and the peaks were monitored at 217 nm. Results: All calibration curves showed good linearity (r ≥ 0.9995 within test ranges. This method showed good repeatability for the quantification of these eleven components in S. chinensis with intra- and inter-day relative standard deviations less than 0.43% and 1.21%, respectively. In the recovery test, results of accuracy ranged from 99.51% to 101.31% with RSD values less than 2.68%, Conclusion: The validated method can be successfully applied to quantify the eleven investigated components in 22 samples of S. chinensis from different sources.

  5. Variation in volatile leaf oils of eleven eucalyptus species harvested from korbous arboreta (Tunisia).

    Science.gov (United States)

    Elaissi, Ameur; Medini, Hanène; Larbi Khouja, Mohamed; Simmonds, Monique; Lynene, Fréderic; Farhat, Farhat; Chemli, Rachid; Harzallah-Skhiri, Fethia

    2010-07-01

    Hydrodistillation of the dried leaves of eleven species of the genus Eucalyptus L'Hér., i.e., E. astringens Maiden, E. camaldulensis Dehnh., E. diversifolia Bonpl., E. falcata Turcz., E. ficifolia F. Muell., E. gomphocephala DC., E. lehmannii (Schauer) Benth., E. maculata Hook., E. platypus Hook., E. polyanthemos Schauer, and E. rudis Endl., harvested from Korbous arboreta (region of Nabeul, northeast of Tunisia) in April 2006, afforded essential oils in yields varying from 0.1+/-0.1 to 3.8+/-0.1%, dependent on the species. E. astringens and E. ficifolia showed the highest and the lowest mean percentage of essential oil amongst all the species examined, respectively. Analysis by GC (RI) and GC/MS allowed the identification of 138 components, representing 74.0 to 99.1% of the total oil. The contents of the different samples varied according to the species. The main components were 1,8-cineole, followed by trans-pinocarveol (1), spathulenol (2), alpha-pinene, p-cymene, (E,E)-farnesol, cryptone, globulol (3), beta-phellandrene, alpha-terpineol, viridiflorol, and alpha-eudesmol. The principal-component and the hierarchical-cluster analyses separated the eleven Eucalyptus leaf essential oils into seven groups, each constituting a chemotype.

  6. Deformations of gauged SO(8) supergravity and supergravity in eleven dimensions

    Science.gov (United States)

    de Wit, Bernard; Nicolai, Hermann

    2013-05-01

    Motivated by the fact that there exists a continuous one-parameter family of gauged SO(8) supergravities, possible eleven-dimensional origins of this phenomenon are explored. Taking the original proof of the consistency of the truncation of 11 D supergravity to SO(8) gauged supergravity as a starting point, a number of critical issues is discussed, such as the preferred electric-magnetic duality frame in four dimensions and the existence of dual magnetic gauge fields and related quantities in eleven dimensions. Some of those issues are resolved but others seem to point to obstructions in embedding the continuous degeneracy in 11 D supergravity. While the final outcome of these efforts remains as yet inconclusive, several new results are obtained. Among those is the full non-linear ansatz for the seven-dimensional flux expressed in terms of the scalars and pseudoscalars of 4 D supergravity, valid for both the S 7 and the T 7 truncations without resorting to tensor-scalar duality.

  7. Factores relacionados con la no participación en el programa de detección precoz de cáncer de mama Factors related to non-participation in a breast cancer early detection program

    Directory of Open Access Journals (Sweden)

    Pilar Barroso García

    2009-02-01

    Full Text Available Objetivo: Conocer las causas de no participación en el Programa de Detección Precoz de Cáncer de Mama (PDPCM en mujeres del Área de Gestión Sanitaria Norte de Almería. Métodos: Estudio de casos y controles. Se eligió una muestra de mujeres invitadas a participar en el PDPCM, entre octubre de 2002 y febrero de 2004. Se recogieron las variables sociodemográficas y las cargas familiares, las variables relacionadas con el programa (conocimiento, accesibilidad, actitudes, los antecedentes familiares y personales, y el estado de salud. Se analizó si había diferencias entre las mujeres que acudieron al programa y las que no, mediante análisis bivariado, y multivariado mediante regresión logística. Se calculó la odds ratio (OR y su intervalo de confianza del 95% (IC95%. Resultados: Se realizaron 720 encuestas 350 casos y 370 controles. Se sustituyó a 291 mujeres (un 40,4% de la muestra. Las variables que de forma independiente se encontraron asociadas a no acudir al programa fueron no recibir carta (OR=11,2; IC95%: 4,6-26,9, haberse realizado mamografía fuera del programa (OR=4,4; IC95%: 2,8-6,9, no tener enfermedades que requieren revisiones médicas (OR=2; IC95%: 1,3-3 y manifestar miedo al resultado de la mamografía (OR=1,8; IC95%: 1,2-2,6. Conclusiones: Se ha encontrado un mayor riesgo de no acudir al programa en las mujeres que no han recibido carta o que tienen una mamografía realizada fuera del programa, y de ahí la necesidad de mejorar la depuración de la base de datos. Hay que seguir divulgando el programa y realizando educación sanitaria en las mujeres con miedo al resultado.Objective: To determine the causes of non-participation in a breast cancer early detection program for women in the northern area of Almería (Spain. Methods: We performed a case-control study. A sample of women included in a breast cancer early detection program between October 2002 and February 2004 was chosen. Participants were interviewed about

  8. The repellent efficacy of eleven essential oils against adult Dermacentor reticulatus ticks.

    Science.gov (United States)

    Štefanidesová, Katarína; Škultéty, Ľudovít; Sparagano, Olivier A E; Špitalská, Eva

    2017-08-01

    Dermacentor reticulatus ticks are among the most important arthropod vectors of zoonotic disease agents in Europe. Eleven essential oils, namely basil (Ocimum basilicum), bergamot (Citrus bergamia), clove bud (Syzygium aromaticum), citronella (Cymbopogon winterianus), creeping thyme (Thymus serpyllum), lavender (Lavandula angustifolia), lemon-scented gum (Corymbia citriodora), marjoram (Origanum majorana), peppermint (Mentha piperita), spearmint (M. spicata), and red thyme (Thymus vulgaris) were tested for repellency against adult D. reticulatus ticks at concentrations of 1 and 3%. Clove bud, creeping thyme and red thyme essential oils were the most efficient - repelling 83, 82 and 68% of ticks when diluted to 3%, respectively. The mixture of creeping thyme and citronella containing 1.5% of each showed higher repellency (91%) than individual essential oils at the concentration of 3%. Copyright © 2017 Elsevier GmbH. All rights reserved.

  9. Ectodermal Dysplasia: Report and Analysis of Eleven South Indian Patients with Review of Literature

    Directory of Open Access Journals (Sweden)

    Renuka Ammanagi

    2010-01-01

    Full Text Available Ectodermal dysplasia represents a rare syndrome affecting two or more ectodermally derived structures. The condition is thought to occur in approximately 1 in every 100,000 live births. It affects men more frequently and severely, while women being the carriers and heterozygote usually show minor defects. There are more than 150 different variants of ectodermal dysplasia (ED reported in the literature. Most commonly encountered among them is hypohidrotic ED which frequently exhibits the most severe dental anomalies like hypodontia or anodontia along with hypohidrosis and hypotrichosis. Here we make an attempt to collectively report and discuss eleven South Indian patients who reported to our department during the year 1998 to 2004. An added emphasis is laid on family history of consanguineous marriage among the parents of these patients.

  10. Eleven Novel Polymorphic Microsatellite Loci for Oval Squid Sepioteuthis Lessoniana (Shiro-Ika Type)

    Science.gov (United States)

    Tomano, Satoshi; Ahmad-Syazni, Kamarudin; Ueta, Yukio; Ohara, Kenichi; Umino, Tetsuya

    2013-01-01

    The oval squid Sepioteuthis lessoniana is one of the most economically important squid species in Japan; however, its population structure is poorly understood due to the lack of hypervariable markers. Such information is critical for managing sustainable fisheries, as well as for ensuring the existence of wild S. lessoniana stocks. Eleven candidate microsatellite loci were isolated from a small insert genomic DNA library. Polymorphisms in these 11 loci were screened in 24 wild individuals. The number of alleles per locus was found to range from 5 to 19 alleles, and the observed heterozygosity ranged from 0.292 to 0.958. No evidence for linkage disequilibrium was detected among all the loci. The genotypic proportions conformed to Hardy-Weinberg equilibrium, except at one locus. In conclusion, these polymorphic microsatellite loci may be used to develop a genetic framework to manage S. lessoniana in the future. PMID:24108369

  11. Teaching Process Simulation in Eleven Easy Lessons Using Excel and Its Tools

    Science.gov (United States)

    Morris, Arthur E.

    The primary market driver for improving process technology is innovation, which requires a skilled and educated workforce. However, many Materials Science and Engineering departments have eliminated extractive metallurgy and chemical thermodynamics from their curricula, yet these topics contain the necessary fundamentals for process innovation. As a result, most MS&E students are ill-prepared for careers in processing. The dearth of process-oriented MS&E curricula has prompted some Universities to develop a "shared" effort to offer distance education between multiple institutions [1]. A target audience for a shared process simulation course would not only benefit students, but also be a basis for an on-line course for practicing engineers faced with new or changing career choices. To fill the gap, the basics of a process simulation course was developed in an abbreviated form as series of eleven articles and Excel workbooks published in Industrial Heating magazine between July 2012 and July 2013.

  12. Global patterns of domestic cannabis cultivation: sample characteristics and patterns of growing across eleven countries.

    Science.gov (United States)

    Potter, Gary R; Barratt, Monica J; Malm, Aili; Bouchard, Martin; Blok, Thomas; Christensen, Anne-Sofie; Decorte, Tom; Frank, Vibeke Asmussen; Hakkarainen, Pekka; Klein, Axel; Lenton, Simon; Perälä, Jussi; Werse, Bernd; Wouters, Marije

    2015-03-01

    This article aims to provide an overview of: demographic characteristics; experiences with growing cannabis; methods and scale of growing operations; reasons for growing; personal use of cannabis and other drugs; participation in cannabis and other drug markets; contacts with the criminal justice system for respondents to an online survey about cannabis cultivation drawn from eleven countries (N=6530). Important similarities and differences between the national samples recruited will be discussed. This paper utilizes data from the online web survey of predominantly 'small-scale' cannabis cultivators in eleven countries conducted by the Global Cannabis Cultivation Research Consortium (GCCRC). Here we focus primarily on descriptive statistics to highlight key similarities and differences across the different national samples. Overall there was a great deal of similarity across countries in terms of: demographic characteristics; experiences with growing cannabis; methods and scale of growing operations; reasons for growing; use of cannabis and other drugs; participation in cannabis and other drug markets, and; contacts with the criminal justice system. In particular, we can recognise that a clear majority of those small-scale cannabis cultivators who responded to our survey are primarily motivated for reasons other than making money from cannabis supply and have minimal involvement in drug dealing or other criminal activities. These growers generally come from 'normal' rather than 'deviant' backgrounds. Some differences do exist between the samples drawn from different countries suggesting that local factors (political, geographical, cultural, etc.) may have some influence on how small-scale cultivators operate, although differences in recruitment strategies in different countries may also account for some differences observed. Copyright © 2014 Elsevier B.V. All rights reserved.

  13. Best Practices in Student Recruitment: A Case Study of Eleven Practitioners at Seven Alternative Graduate Schools

    Science.gov (United States)

    Chow, Sheri S. L.

    2012-01-01

    This research addresses best practices for recruiting students at small graduate schools. Best practice is a management term defined as the most efficient and effective way of accomplishing a task. While popular techniques can promote student enrollment, the actual practices and how they are carried out can be varied and unique at each school. For…

  14. Atypical Teratoid/ Rhabdoid Tumor of Brain: a Clinicopathologic Study of Eleven Patients and Review of Literature

    Science.gov (United States)

    Ud Din, Nasir; Barakzai, Abrar; Memon, Aisha; Hasan, Sheema; Ahmad, Zubair

    2017-04-01

    Background: Atypical teratoid/ rhabdoid tumor (AT/RT) is a rare aggressive embryonal central nervous system (CNS) tumor of infancy and early childhood. Majority of the cases arise in the posterior fossa, and remaining in the cerebrum. Aims: To analyze the clinicopathologic features of AT/RT on a cohort of cases. Materials and methods: All reported cases of AT/RT at the Department of Pathology and Laboratory Medicine, Aga Khan University Hospital (AKUH) from 2007 to 2016 were reviewed for clinical and pathological features. Immunohistochemical stain for INI-1 was performed in all 11 cases. Follow up was obtained. Results: A total of 11 cases were identified. Seven patients were males and 4 were females. The ages ranged from 1 month to 48 months (mean 26.6 months). Six tumors were located in the cerebrum and 3 in the posterior fossa. Exact Location was not known in 2 cases. Histologically, rhabdoid cells were present in sheets in variable proportions in five cases, Medulloblastoma and PNET like areas were seen in 2 cases each. Immunohistochemical stains EMA (10/10), vimentin (7/7), CKAE1/AE3 (8/9), and CD99 (3/4), GFAP (6/10), ASMA (3/4) and synaptophysin (3/4) were positive in varying proportions while desmin was negative in all 6 cases in which it was performed. All 11 tumors lacked immunoreactivity for INI-1 protein. Four patients died of disease with a follow up ranging from 5 to 24 months. Conclusions: AT/RT is a rare highly aggressive embryonal tumor of CNS. A male predominance was noted in our series. We report the first and largest series from Pakistan. Creative Commons Attribution License

  15. Behcet's syndrome and renal involvement: a histological and immunofluorescent study of eleven renal biopsies.

    Science.gov (United States)

    Herreman, G; Beaufils, H; Godeau, P; Cassou, B; Wechsler, B; Boujeau, J; Chomette, G

    1982-01-01

    The finding of focal glomerulonephritis in a patient with Behcet's syndrome led us to perform systematic renal biopsies in ten other patients with the disease. None of the patients had symptoms of renal disease. Proteinuria was found in five, two of whom had associated leukocyturia. By light microscopy mesangial and extramembranous glomerular deposits were observed in eight patients. Arterioles in ten patients showed subendothelial and medial hyaline deposits. A granular pattern of fluorescent staining identified the presence of the third component of complement in these deposits. Circulating immune deposits were sought and found in six out of seven patients. The finding of circulating immune complexes and deposition of complement in glomerular and arteriolar tissues supports an immune complex mediated nephropathy and is consistent with the hypothesis of an immunological pathogenesis in Behcet's syndrome.

  16. Bedrock geologic map of the Spring Valley, West Plains, and parts of the Piedmont and Poplar Bluff 30'x60' quadrangles, Missouri, including the upper Current River and Eleven Point River drainage basins

    Science.gov (United States)

    Weary, David J.; Harrison, Richard W.; Orndorff, Randall C.; Weems, Robert E.; Schindler, J. Stephen; Repetski, John E.; Pierce, Herbert A.

    2015-01-01

    This map covers the drainage basins of the upper Current River and the Eleven Point River in the Ozark Plateaus physiographic province of southeastern Missouri. The two surface drainage basins are contiguous in their headwaters regions, but are separated in their lower reaches by the lower Black River basin in the southeast corner of the map area. Numerous dye-trace studies demonstrate that in the contiguous headwaters areas, groundwater flows from the Eleven Point River basin into the Current River basin. Much of the groundwater discharge of the Eleven Point River basin emanates from Big Spring, located on the Current River. This geologic map and cross sections were produced to help fulfill a need to understand the geologic framework of the region in which this subsurface flow occurs.

  17. Predicting the variability of water resources in eleven global river basins using multivariate and decision tree analysis with satellite data

    Science.gov (United States)

    Fayne, J.; Lakshmi, V.

    2016-12-01

    The increasing trend of floods and droughts over the past decade has made the study of hydrologic processes and water availability vital to our understanding of extreme hydrologic events. As extreme events result in thousands of lives lost in addition to billions in property damage, many of these extreme events occur in developing countries where in-situ observing networks are sparse making forecasting and estimation of impacts near impossible. Eleven river basins around the globe are analyzed using satellite and modeled data from NASA to compute these patterns globally and begin to understand and predict extreme events based on fluctuations in ground water modeled by the GRACE tandem satellite. This study assesses how the water cycle variables such as precipitation, soil moisture, runoff, evapotranspiration and vegetation have changed over the past 15 years, focusing on climate systems represented by the 2007 Koppen Climate Classification. Monthly trends using GRACE Water Equivalent Thickness Anomaly, TRMM and GPM Precipitation, MODIS NDVI and ET, and GLDAS Runoff and Root Zone Soil moisture are analyzed using a combination of multivariate regression and decision tree classification at sub-basin climate level. The result of these analyses yields predicted Water Equivalent Thickness Anomaly maps that are climate specific with a higher resolution, up to 250 meters, compared to the GRACE 100 km product.

  18. Nosocomial infection characteristics in a burn intensive care unit: analysis of an eleven-year active surveillance.

    Science.gov (United States)

    Öncül, Oral; Öksüz, Sinan; Acar, Ali; Ülkür, Ersin; Turhan, Vedat; Uygur, Fatih; Ulçay, Asım; Erdem, Hakan; Özyurt, Mustafa; Görenek, Levent

    2014-08-01

    The objective of this study was to describe nosocomial infection (NI) rates, risk factors, etiologic agents, antibiotic susceptibility, invasive device utilization and invasive device associated infection rates in a burn intensive care unit (ICU) in Turkey. Prospective surveillance of nosocomial infections was performed according to Centers for Disease Control and Prevention (CDC) and National Healthcare Safety Network (NHSN) criteria between 2001 and 2012. The data was analyzed retrospectively. During the study period 658 burn patients were admitted to our burn ICU. 469 cases acquired 602 NI for an overall NI rate of 23.1 per 1000 patient days. 109 of all the cases (16.5%) died. Pseudomonas aeruginosa (241), Acinetobacter baumannii (186) and Staphylococcus aureus (69) were the most common identified bacteria in 547 strains. Total burn surface area, full thickness burn, older age, presence of inhalation injury were determined to be the significant risk factors for acquisition of NI. Determining the NI profile at a certain burn ICU can lead the medical staff apply the appropriate treatment regimen and limit the drug resistance. Eleven years surveillance report presented here provides a recent data about the risk factors of NI in a Turkish burn ICU. Copyright © 2013 Elsevier Ltd and ISBI. All rights reserved.

  19. Matematisk forståing: Kva legg eleven i omgrepet matematisk forståing, og korleis jobbar eleven for å tileigna seg forståing i matematikk?

    OpenAIRE

    2015-01-01

    Formålet bak forskings og utviklingsarbeidet mitt var å danna eit bilete av kva faktorar som bidreg til læring i matematikkfaget hos elevane. Eg valde dette fokusområdet for undersøkinga slik at eg som framtidig matematikklærar kan vera rusta til å rettleia elevane mot å utvikle forståing i matematikk. Difor lydar problemstillinga som følgjar: «Kva legg eleven i omgrepet matematisk forståing, og korleis jobbar eleven for å tileigna seg forståing i matematikk?» I teorikapittelet presenterer eg...

  20. Isolation and Characterization of Eleven Polymorphic Microsatellite Loci for the Valuable Medicinal Plant Dendrobium huoshanense and Cross-Species Amplification

    Directory of Open Access Journals (Sweden)

    Hui Wang

    2012-12-01

    Full Text Available Dendrobium huoshanense (Orchidaceae is a perennial herb and a widely used medicinal plant in Traditional Chinese medicine (TCM endemic to Huoshan County town in Anhui province in Southeast China. A microsatellite-enriched genomic DNA library of D. huoshanense was developed and screened to identify marker loci. Eleven polymorphic loci were isolated and analyzed by screening 25 individuals collected from a natural population. The number of alleles per locus ranged from 2 to 5. The observed and expected heterozygosities ranged from 0.227 to 0.818 and from 0.317 to 0.757, respectively. Two loci showed significant deviations from Hardy-Weinberg equilibrium and four of the pairwise comparisons of loci revealed linkage disequilibrium (p < 0.05. These microsatellite loci were cross-amplified for five congeneric species and seven loci can be amplified in all species. These simple sequence repeats (SSR markers are useful in genetic studies of D. huoshanense and other related species and in conservation decision-making.

  1. Three-layered osteodural plasty for severe anterior skull base and facial injuries. Report of eleven cases.

    Science.gov (United States)

    Wanyura, Hubert; Kamiński, Artur; Stopa, Zygmunt

    2014-01-01

    The upper cranial trauma of high force and wide area of application leads to fractures of calvaria, the skull base, and the viscerocranium. The aim of the study was to present eleven patients treated for severe anterior skull base and facial defects by means of three-layered osteodural plasty. The operative tactics consisted of bicoronal incision, bifrontal craniotomy, closure of the dura mater damage with a pericranium, reconstruction of bone defects with autologous bone grafts and plasty with anteriorly pedicled pericranial flap on the supratrochlear and supraorbital vessels. During follow-up, which lasted 2-7 years, none of the patients developed any early or late postoperative complications. The three-layer osteodural plasty of severe anterior skull base injuries with the use of autologous bone grafts for the reconstruction of craniofacial skeleton resulted in a good final functional, morphological and aesthetic outcome in all patients. Copyright © 2014 Polish Neurological Society. Published by Elsevier Urban & Partner Sp. z o.o. All rights reserved.

  2. Evaluation of Eleven Macro and Micro Elements Present in Various Hybrids of Millet (Pennisetum glaucum, or P. Americanum

    Directory of Open Access Journals (Sweden)

    Ghulam Qadir Shar

    2012-06-01

    Full Text Available Maize and Millet Research Institute (MMRI situated in Yousuf wala, District Sahiwal, Punjab, Pakistan was selected to grow nine different hybrids/cultivars of millet for study to comprehend the variable concentration of macro, micro and trace and toxic elements in their grains. Wet digestion method was used for the preparation of samples and flame atomic absorption spectrophotometer for analysis of eleven major and minor elements. High values of macro-elements i.e. sodium and potassium was found in ICMP-451 and magnesium in ICMP-53506. The high value of essential micro-elements i.e.zinc (50mg/kg, manganese (8mg/kg, and copper (8mg/kg was calculated in ICMP-53506, Bullo-94-1, and ICMP-83720 respectively. In case of trace and toxic micro-elements, high concentration of nickel, cobalt, chromium and cadmium was found in O.B.V, Bullo-7704, ICMP-83401, and ICMP-83720 in the edible part of millet plants (grains cultivars respectively.

  3. The Academic Reward System is the Primary Influence Toward Faculty Non-Participation in Institutional Repositories. A review of: Davis, Phillip M., and Matthew J.L. Connolly. “Institutional Repositories: Evaluating the Reasons for Non‐Use of Cornell University’s Installation of DSpace.” D‐Lib Magazine 13.3/4 (2007. 16 Oct. 2007 .

    Directory of Open Access Journals (Sweden)

    Kurt Blythe

    2007-12-01

    Full Text Available Objective – To better understand the lack of faculty participation in Cornell University’s DSpace institutional repository (IR, and to learn if this lack of participation is peculiar to Cornell or reflective of a larger trend in faculty non-participation in IRs.Design – Comparative analysis and interviews.Setting – Cornell University’s DSpace IR and sciences, social sciences, and humanities faculties; and DSpace installations at 7 other universities.Subjects – The DSpace IR at Cornell University and at 7 other locations. Eleven sciences, social sciences, and humanities faculty members at Cornell University.Methods – The authors analyzed data over a fifteen‐month period from Cornell’s DSpace IR to determine the total deposits, the types of objects deposited, the communities and collections that received deposits, the frequency of deposits, the IP addresses which made deposits, and how often objects in the IR were viewed. These data were compared to equivalent data taken from seven other IRs on all aspects except deposits from IP addresses and how oftenobjects were viewed. Finally, 11 Cornell faculty members from various departments in the sciences, social sciences, and humanities were interviewed over a two month period to provide context to the comparative analysis.Main results – At the time of the study, the IR at Cornell was organized into 193 communities of collections. These collections numbered 196, with 139 of them holding a combined total of 2646 objects: The other 57 collections were empty. While the IR as a whole showed steady growth, 77% of Cornell’s collections reflected a plateau growth pattern of primarily “one time deposits,” approximately 18% exhibited a stair‐step growth pattern of“periodic batch additions of material,” approximately 3% showed steady growth, and 1.4% were “uncatagorizable.” Five hundred nineteen unique IP addresses made deposits to Cornell’s IR over the course of the fifteen

  4. Photocatalytic degradation of eleven microcystin variants and nodularin by TiO2 coated glass microspheres.

    Science.gov (United States)

    Pestana, Carlos J; Edwards, Christine; Prabhu, Radhakrishna; Robertson, Peter K J; Lawton, Linda A

    2015-12-30

    Microcystins and nodularin are toxic cyanobacterial secondary metabolites produced by cyanobacteria that pose a threat to human health in drinking water. Conventional water treatment methods often fail to remove these toxins. Advanced oxidation processes such as TiO2 photocatalysis have been shown to effectively degrade these compounds. A particular issue that has limited the widespread application of TiO2 photocatalysis for water treatment has been the separation of the nanoparticulate powder from the treated water. A novel catalyst format, TiO2 coated hollow glass spheres (Photospheres™), is far more easily separated from treated water due to its buoyancy. This paper reports the photocatalytic degradation of eleven microcystin variants and nodularin in water using Photospheres™. It was found that the Photospheres™ successfully decomposed all compounds in 5 min or less. This was found to be comparable to the rate of degradation observed using a Degussa P25 material, which has been previously reported to be the most efficient TiO2 for photocatalytic degradation of microcystins in water. Furthermore, it was observed that the degree of initial catalyst adsorption of the cyanotoxins depended on the amino acid in the variable positions of the microcystin molecule. The fastest degradation (2 min) was observed for the hydrophobic variants (microcystin-LY, -LW, -LF). Suitability of UV-LEDs as an alternative low energy light source was also evaluated.

  5. Anthocyanins and other flavonoids as flower pigments from eleven Centaurea species.

    Science.gov (United States)

    Mishio, Tamaki; Takeda, Kosaku; Iwashina, Tsukasa

    2015-03-01

    Anthocyanins and other flavonoids were isolated from the flowers of eleven Centaurea species, C. macrocephala, C. rupestotilis and C. suaveolens, which produce yellow flowers, and C. achtarovii, C. dealbata, C. montana, C. nigra, C. scabiosa, C. simplicicaulis, C. hypoleuca and C. triumfetti, which have cyanic flowers. Four anthocyanins, cyanidin 3,5-di-O-glucoside, cyanidin 3-O-(6"-malonylglucoside)-5-O-glucoside, cyanidin 3-O-(6"-succinylglucoside)-5- O-glucoside and cyanidin glycoside, were detected in the cyanic flowers of seven Centaurea species. Of these anthocyanins, the first two were found as major anthocyanins. In the cyanic species, four other flavonoids, apigenin 7-O-glucuronide-4'-O-glucoside, malonylated apigenin 7,4'-di-O-glucoside, apigenin 7-0- glucuronide and kaempferol glycoside, were also isolated. On the other hand, nine flavonols and four flavones were isolated from the three yellow-flowered species, and identified as quercetagetin, quercetagetin 7-O-glucoside, quercetagetin 3'-methyl ether 7-O-glucoside, patuletin, patuletin 7-O-glucoside, quercetin 7-O-glucoside, kaempferol 3-methyl ether, kaempferol 3-methyl ether 4'-O-glucuronide and isorhamnetin 3-O-galactoside, and apigenin, apigenin 7- O-glucuronide, luteolin 7-O-glucoside and apigenin 6,8-di-C-glucoside (vicenin-2). Of these flavonoids, the former five flavonols are "yellow flavonols", and it was shown that their flower colors are due to these compounds.

  6. A mouse chromosome 4 balancer ENU-mutagenesis screen isolates eleven lethal lines

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    Moskowitz Ivan

    2009-03-01

    Full Text Available Abstract Background ENU-mutagenesis is a powerful technique to identify genes regulating mammalian development. To functionally annotate the distal region of mouse chromosome 4, we performed an ENU-mutagenesis screen using a balancer chromosome targeted to this region of the genome. Results We isolated 11 lethal lines that map to the region of chromosome 4 between D4Mit117 and D4Mit281. These lines form 10 complementation groups. The majority of lines die during embryonic development between E5.5 and E12.5 and display defects in gastrulation, cardiac development, and craniofacial development. One line displayed postnatal lethality and neurological defects, including ataxia and seizures. Conclusion These eleven mutants allow us to query gene function within the distal region of mouse chromosome 4 and demonstrate that new mouse models of mammalian developmental defects can easily and quickly be generated and mapped with the use of ENU-mutagenesis in combination with balancer chromosomes. The low number of mutations isolated in this screen compared with other balancer chromosome screens indicates that the functions of genes in different regions of the genome vary widely.

  7. Osteogenesis imperfecta type V: Genetic and clinical findings in eleven Chinese patients.

    Science.gov (United States)

    Liu, Yi; Wang, Jiawei; Ma, Doudou; Lv, Fang; Xu, Xiaojie; Xia, Weibo; Jiang, Yan; Wang, Ou; Xing, Xiaoping; Zhou, Peiran; Wang, Jianyi; Yu, Wei; Li, Mei

    2016-11-01

    Osteogenesis imperfecta (OI) type V is a rare inherited disease characterized by multiple fractures, intraosseous membrane calcification, and hypercallus formation. We investigate the causative gene, phenotype and also observe the effects of zoledronic acid in Chinese OI type V patients. The clinical phenotype and causative gene mutation was investigated in eleven patients with type V OI. Patients were given a dose of zoledronic acid 5mg intravenously. Fracture incidence and Z-score of bone mineral density (BMD) were evaluated. Serum levels of biomarkers such as cross linked C-telopeptide of type I collagen (β-CTX) and safety parameters were assessed. The c.-14C>T mutation in the 5' untranslated region of IFITM5 was detected in all patients. The phenotype was largely variable, and no significant correlation of genotype and phenotype was found. After one dose of zoledronic acid infusion, fracture incidence significantly dropped from 2fractures/year before treatment to 0fracture/year after treatment (P=0.01). Z score of lumbar spine BMD elevated from -2.6 to -1.3 (P<0.001). Serum β-CTX level decreased by 50% (P<0.05). No serious adverse event was found. No obvious correlation was found between the genotype and phenotype. Zoledronic acid had significantly skeletal protective effects in OI of type V. Copyright © 2016 Elsevier B.V. All rights reserved.

  8. Comparative transcriptome resources of eleven Primulina species, a group of 'stone plants' from a biodiversity hot spot.

    Science.gov (United States)

    Ai, Bin; Gao, Yong; Zhang, Xiaolong; Tao, Junjie; Kang, Ming; Huang, Hongwen

    2015-05-01

    The genus Primulina is an emerging model system in studying the drivers and mechanisms of species diversification, for its high species richness and endemism, together with high degree of habitat specialization. In this study, we sequenced transcriptomes for eleven Primulina species across the phylogeny of the genus using the Illumina HiSeq 2000 platform. A total of 336 million clean reads were processed into 355 573 unigenes with a mean length of 1336 bp and an N50 value of 2191 bp after pooling and reassembling twelve individual pre-assembled unigene sets. Of these unigenes, 249 973 (70%) were successfully annotated and 256 601 (72%) were identified as coding sequences (CDSs). We identified a total of 38 279 simple sequence repeats (SSRs) and 367 123 single nucleotide polymorphisms (SNPs). Marker validation assay revealed that 354 (27.3%) of the 1296 SSR and 795 (39.6%) of the 2008 SNP loci showed successful genotyping performance and exhibited expected polymorphism profiles. We screened 834 putative single-copy nuclear genes and proved their high effectiveness in phylogeny construction and estimation of ancestral population parameters. We identified a total of 85 candidate orthologs under positive selection for 46 of the 66 species pairs. This study provided an efficient application of RNA-seq in development of genomic resources for a group of 'stone plants' from south China Karst regions, a biodiversity hot spot of the World. The assembled unigenes with annotations and the massive gene-associated molecular markers would help guide further molecular systematic, population genetic and ecological genomics studies in Primulina and its relatives. © 2014 John Wiley & Sons Ltd.

  9. The distribution of fruit and seed toxicity during development for eleven neotropical trees and vines in Central Panama.

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    Noelle G Beckman

    Full Text Available Secondary compounds in fruit mediate interactions with natural enemies and seed dispersers, influencing plant survival and species distributions. The functions of secondary metabolites in plant defenses have been well-studied in green tissues, but not in reproductive structures of plants. In this study, the distribution of toxicity within plants was quantified and its influence on seed survival was determined in Central Panama. To investigate patterns of allocation to chemical defenses and shifts in allocation with fruit development, I quantified variation in toxicity between immature and mature fruit and between the seed and pericarp for eleven species. Toxicity of seed and pericarp was compared to leaf toxicity for five species. Toxicity was measured as reduced hyphal growth of two fungal pathogens, Phoma sp. and Fusarium sp., and reduced survivorship of brine shrimp, Artemia franciscana, across a range of concentrations of crude extract. I used these measures of potential toxicity against generalist natural enemies to examine the effect of fruit toxicity on reductions of fruit development and seed survival by vertebrates, invertebrates, and pathogens measured for seven species in a natural enemy removal experiment. The seed or pericarp of all vertebrate- and wind-dispersed species reduced Artemia survivorship and hyphal growth of Fusarium during the immature and mature stages. Only mature fruit of two vertebrate-dispersed species reduced hyphal growth of Phoma. Predispersal seed survival increased with toxicity of immature fruit to Artemia during germination and decreased with toxicity to fungi during fruit development. This study suggests that fruit toxicity against generalist natural enemies may be common in Central Panama. These results support the hypothesis that secondary metabolites in fruit have adaptive value and are important in the evolution of fruit-frugivore interactions.

  10. The distribution of fruit and seed toxicity during development for eleven neotropical trees and vines in Central Panama.

    Science.gov (United States)

    Beckman, Noelle G

    2013-01-01

    Secondary compounds in fruit mediate interactions with natural enemies and seed dispersers, influencing plant survival and species distributions. The functions of secondary metabolites in plant defenses have been well-studied in green tissues, but not in reproductive structures of plants. In this study, the distribution of toxicity within plants was quantified and its influence on seed survival was determined in Central Panama. To investigate patterns of allocation to chemical defenses and shifts in allocation with fruit development, I quantified variation in toxicity between immature and mature fruit and between the seed and pericarp for eleven species. Toxicity of seed and pericarp was compared to leaf toxicity for five species. Toxicity was measured as reduced hyphal growth of two fungal pathogens, Phoma sp. and Fusarium sp., and reduced survivorship of brine shrimp, Artemia franciscana, across a range of concentrations of crude extract. I used these measures of potential toxicity against generalist natural enemies to examine the effect of fruit toxicity on reductions of fruit development and seed survival by vertebrates, invertebrates, and pathogens measured for seven species in a natural enemy removal experiment. The seed or pericarp of all vertebrate- and wind-dispersed species reduced Artemia survivorship and hyphal growth of Fusarium during the immature and mature stages. Only mature fruit of two vertebrate-dispersed species reduced hyphal growth of Phoma. Predispersal seed survival increased with toxicity of immature fruit to Artemia during germination and decreased with toxicity to fungi during fruit development. This study suggests that fruit toxicity against generalist natural enemies may be common in Central Panama. These results support the hypothesis that secondary metabolites in fruit have adaptive value and are important in the evolution of fruit-frugivore interactions.

  11. The NANOGrav Eleven-Year Data Set: High-precision timing of 48 Millisecond Pulsars

    Science.gov (United States)

    Nice, David J.; NANOGrav

    2017-01-01

    Gravitational waves from sources such as supermassive black hole binary systems perturb times-of-flight of signals traveling from pulsars to the Earth. The NANOGrav collaboration aims to measure these perturbations in high precision millisecond pulsar timing data and thus to directly detect gravitational waves and characterize the gravitational wave sources. By observing pulsars over time spans of many years, we are most sensitive to gravitational waves at nanohertz frequencies. This work is complimentary to ground based detectors such as LIGO, which are sensitive to gravitational waves with frequencies 10 orders of magnitude higher.In this presentation we describe the NANOGrav eleven-year data set. This includes pulsar time-of-arrival measurements from 48 millisecond pulsars made with the Arecibo Observatory (for pulsars with declinations between -1 and 39 degrees) and the Green Bank Telescope (for other pulsars, with two pulsars overlapping with Arecibo). The data set consists of more than 300,000 pulse time-of-arrival measurements made in nearly 7000 unique observations (a given pulsar observed with a given telescope receiver on a given day). In the best cases, measurement precision is better than 100 nanoseconds, and in nearly all cases it is better than 1 microsecond.All pulsars in our program are observed at intervals of 3 to 4 weeks. Observations use wideband data acquisition systems and are made at two receivers at widely separated frequencies at each epoch, allowing for characterization and mitigation of the effects of interstellar medium on the signal propagation. Observation of a large number of pulsars allows for searches for correlated perturbations among the pulsar signals, which is crucial for achieving high-significance detection of gravitational waves in the face of uncorrelated noise (from gravitational waves and rotation noise) in the individual pulsars. In addition, seven pulsars are observed at weekly intervals. This increases our sensitivity

  12. Acute Disseminated Encephalomyelitis: A Review of Eleven Cases in Childhood in North of Iran

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    Ali Nikkhah

    2016-01-01

    Full Text Available Background: Acute disseminated encephalomyelitis (ADEM is an inflammatory demyelinating disorder. The pathogenesis is unclear, but it is thought to be immune-mediated. The prognosis is favorable, with most children making a full recovery. Objectives: The present report analyzed different clinical presentations, response to treatment and outcome in a series of 11 patients with ADEM who referred to our tertiary center in north of Iran from 2010 to 2014. Materials and Methods: In this retrospective simple descriptive review, eleven cases with ADEM admitted in the neurology ward from 2010 to 2014 were enrolled. The clinical findings and laboratory and imaging results of patients were reviewed. All of these cases were evaluated with neurological examination, serologic tests for bacterial meningitis and viral encephalitis (especially, herpes simplex virus and brain MRI without contrast. After discharge, patients were followed for at least six months (6 to 12 months clinically and radiologically. Results: Of 11 children, 8 were male and 3 female. Their ages ranged between 4 and 10 years. The mean interval between the preceding infection and symptoms of encephalomyelitis was nine days. The most common presenting symptoms were ataxia in 45.4%, fever and headache in 36.4% and altered consciousness in 18.2% of patients. Neurological examination revealed pyramidal motor signs such as brisk deep tendon reflexes (hyperreflexia (81.8%, cranial nerve involvement (18.2%, dysarthria (9.1% and abnormal movements (9.1%. We followed up these patients in long-term for 6 to 12 months. Only in 1 child who received IVIG, mild ataxia had reminded. Conclusions: The prognosis of acute disseminated encephalomyelitis (ADEM is favorable. Early diagnosis and prompt treatment of ADEM would probably reduce morbidity.

  13. Total midgut volvulus in adults with intestinal malrotation. Report of eleven patients.

    Science.gov (United States)

    Kotobi, H; Tan, V; Lefèvre, J; Duramé, F; Audry, G; Parc, Y

    2017-06-01

    Total small-intestinal volvulus with malrotation (TSIVM) classically presents in the neonatal period; it occurs much less frequently in the adult and is often misdiagnosed. Prognosis is directly related to the degree and duration of intestinal ischemia. Our goal is to describe our experience with TSIVM in the adult, to identify any specific findings and to discuss its management. Eleven patients who had undergone surgery for TSIVM at three centers between 1992 and 2012 were included. Surgery was performed as an emergency for five patients and surgery was elective for six. Mean follow-up was 63 months (range: 12-270). Six patients had had previous abdominal surgery. In nine cases, the diagnosis of TSIVM was made preoperatively, mainly by CT scan in eight cases. Seven patients had associated congenital failure of retroperitoneal fixation of the right colon and all of these underwent a Ladd procedure. The mortality rate was zero. Of the five patients who underwent emergency surgery, three required intestinal resections, one of whom developed a short bowel syndrome. The six patients who underwent surgery electively had no surgical complications. TSIVM is a very unusual finding in adult patients. The diagnosis can be made by CT scan with IV and oral contrast, but it often comes to light only at the time of surgery, even though the patients have often had recurrent episodes of abdominal symptomatology that dated back to childhood. The Ladd procedure, consisting of division of Ladd's bands, widening of the mesentery, and incidental appendectomy, remains the standard surgical repair. Digestive surgeons who care for adults should be familiar with this procedure, and it should be performed, as often as possible, with the assistance of a pediatric surgeon. Copyright © 2016. Published by Elsevier Masson SAS.

  14. Analysis of aliphatic waxes associated with root periderm or exodermis from eleven plant species.

    Science.gov (United States)

    Kosma, Dylan K; Rice, Adam; Pollard, Mike

    2015-09-01

    Aliphatic waxes can be found in association with suberized tissues, including roots. Non-polar lipids were isolated by rapid solvent extraction of mature regions of intact roots from eleven angiosperms, including both monocots and dicots. The majority of roots analyzed were taproots or tuberous taproots that had undergone secondary growth and thus were covered by a suberized periderm. The exceptions therein were maize (Zea mays L.) and rice (Oryza sativa L.), which present a suberized exodermis. The analysis herein focused on aliphatic waxes, with particular emphasis on alkyl hydroxycinnamates (AHCs). AHCs were widely distributed, absent from only one species, were found in both aerial and subterranean portions of tuberous taproots, and were associated with the fibrous roots of both maize and rice. Most species also contained monoacylglycerols, fatty alcohols and/or free fatty acids. Carrot (Daucus carrota L.) was the outlier, containing only free fatty acids, sterols, and polyacetylenes as identified components. Sterols were the only ubiquitous component across all roots analyzed. Monoacylglycerols of ω-hydroxy fatty acids were present in maize and rice root waxes. For species within the Brassiceae, wax compositions varied between subspecies or varieties and between aerial and subterranean portions of taproots. In addition, reduced forms of photo-oxidation products of ω-hydroxy oleate and its corresponding dicarboxylic acid (10,18-dihydroxy-octadec-8-enoate, 9,18-dihydroxy-octadec-10-enoate and 9-hydroxyoctadec-10-ene-1,18-dioate) were identified as naturally occurring suberin monomers in rutabaga (Brassica napus subsp. rapifera Metzg.) periderm tissues.

  15. 5-HTTLPR polymorphism of serotonin transporter and effects of sertraline in terminally ill cancer patients: report of eleven cases.

    Science.gov (United States)

    Schillani, Giulia; Capozzo, Maria Anna; Aguglia, Eugenio; De Vanna, Maurizio; Grassi, Luigi; Conte, Maria Anna; Giraldi, Tullio

    2008-01-01

    Depression is difficult to detect in cancer patients, though its determination offers an opportunity to relieve patients' suffering in palliative care. Selective serotonin reuptake inhibitors (SSRIs) are the treatment of choice for mood disorders, but they show a highly variable response. The short allelic variants "s/s" and "s/l" of the 5-HTTLPR polymorphism in the promoter region of the serotonin transporter gene has been consistently associated with a poorer response to SSRIs. The aim of this study has therefore been to examine depression, anxiety and mental adaptation to cancer in terminally ill and depressed cancer patients, in relation to treatment with sertraline and to the 5-HTTLPR genetic polymorphism. Eleven consecutive depressed patients with different forms of advanced cancer who were admitted to the Hospice of the Casa di Cura "Pineta del Carso" (Trieste, Italy) were treated with sertraline for two weeks and their response was determined and related to 5-HTTLPR. Sertraline significantly reduced the average depression and anxiety subscale scores of HADS, as well as the scores of the subscales of Mini-MAC. When the effects of sertraline were analyzed in relation to the 5-HTTLPR polymorphism, only patients with the "l/l" allelic variant had significantly lower scores of HADS anxiety, Mini-MAC hopelessness-helplessness and anxious preoccupation, and a higher score for the fighting spirit of Mini-MAC; the depression score was significantly reduced in patients with both allelic variants. These data indicate that sertraline is effective after two weeks of treatment in terminally ill cancer patients, acting not only on depression but also on anxiety and mental adaptation to cancer. Moreover, the effect of sertraline significantly depended on the genetic polymorphism of the serotonin transporter, being more pronounced in patients carrying the "l/l" genetic variant; these findings seem to encourage the examination of a larger sample of patients.

  16. Post mortem computed tomography and core needle biopsy in comparison to autopsy in eleven Bernese mountain dogs with histiocytic sarcoma.

    Science.gov (United States)

    Hostettler, Franziska C; Wiener, Dominique J; Welle, Monika M; Posthaus, Horst; Geissbühler, Urs

    2015-09-02

    Bernese mountain dogs are reported to have a shorter life expectancy than other breeds. A major reason for this has been assigned to a high tumour prevalence, especially of histiocytic sarcoma. The efforts made by the breeding clubs to improve the longevity with the help of genetic tests and breeding value estimations are impeded by insufficiently reliable diagnoses regarding the cause of death. The current standard for post mortem examination in animals is performance of an autopsy. In human forensic medicine, imaging modalities, such as computed tomography and magnetic resonance imaging, are used with increasing frequency as a complement to autopsy. The present study investigates, whether post mortem computed tomography in combination with core needle biopsy is able to provide a definitive diagnosis of histiocytic sarcoma. For this purpose we have analysed the results of post mortem computed tomography and core needle biopsy in eleven Bernese mountain dogs. In the subsequent autopsy, every dog had a definitive diagnosis of histiocytic sarcoma, based on immunohistochemistry. Computed tomography revealed space-occupying lesions in all dogs. Lesion detection by post mortem computed tomography was similar to lesion detection in autopsy for lung tissue (9 cases in computed tomography / 8 cases in autopsy), thoracic lymph nodes (9/8), spleen (6/7), kidney (2/2) and bone (3/3). Hepatic nodules, however, were difficult to detect with our scanning protocol (2/7). Histology of the core needle biopsies provided definitive diagnoses of histiocytic sarcoma in ten dogs, including confirmation by immunohistochemistry in six dogs. The biopsy samples of the remaining dog did not contain any identifiable neoplastic cells. Autolysis was the main reason for uncertain histological diagnoses. Post mortem computed tomography is a fast and effective method for the detection of lesions suspicious for histiocytic sarcoma in pulmonary, thoracic lymphatic, splenic, osseous and renal tissue

  17. Turbulent natural convection in a differentially heated cavity of aspect ratio 5 filled with non-participating and participating grey media

    Energy Technology Data Exchange (ETDEWEB)

    Capdevila, R; Trias, F X; Perez-Segarra, C D [Centre Tecnologic de Transferencia de Calor (CTTC), Lab.Termotecnia i Energetica, Universitat Politecnica de Catalunya (UPC), C/Colom, 11, E08222 Terrassa, Barcelona (Spain); Lehmkuhl, O; Colomer, G, E-mail: cttc@cttc.upc.edu, E-mail: termofluids@termofluids.com [Termofluids, S. L., Magi Colet 8, E08204 Sabadell, Barcelona (Spain)

    2011-12-22

    In the present work, turbulent natural convection in a tall differentially heated cavity of aspect ratio 5:1, filled with air (Pr = 0.7) under a Rayleigh number based on the height of 4.5 {center_dot} 10{sup 10}, is studied numerically. Two different situations have been analysed. In the first one, the cavity is filled with a transparent medium. In the second one, the cavity contains a grey participating gas. The turbulent flow is described by means of Large Eddy Simulation (LES) using symmetry-preserving discretizations. Simulations are compared with experimental data available in the literature and with Direct Numerical Simulations (DNS). Surface and gas radiation have been simulated using the Discrete Ordinates Method (DOM). The influence of radiation on fluid flow behaviour has also been analysed.

  18. Fast and simultaneous determination of eleven synthetic color additives in flour and meat products by liquid chromatography coupled with diode-array detector and tandem mass spectrometry.

    Science.gov (United States)

    Qi, Ping; Lin, Zi-hao; Chen, Gui-yun; Xiao, Jian; Liang, Zhi-an; Luo, Li-ni; Zhou, Jun; Zhang, Xue-wu

    2015-08-15

    In this study, an efficient, fast and sensitive method for the simultaneous determination of eleven synthetic color additives (Allura red, Amaranth, Azo rubine, Brilliant blue, Erythrosine, Indigotine, Ponceau 4R, New red, Sunset yellow, Quinoline yellow and Tartrazine) in flour and meat foodstuffs is developed and validated using HPLC coupled with DAD and MS/MS. The color additives were extracted with ammonia-methanol and was further purified with SPE procedure using Strata-AW column in order to reduce matrix interference. This HPLC-DAD method is intended for a comprehensive survey of color additives in foods. HPLC-MS/MS method was used as the further confirmation and identification. Validation data showed the good recoveries in the range of 75.2-113.8%, with relative standard deviations less than 15%. These methods are suitable for the routine monitoring analysis of eleven synthetic color additives due to its sensitivity, reasonable time and cost. Copyright © 2015 Elsevier Ltd. All rights reserved.

  19. Comparison of Eleven Methods for Genomic DNA Extraction Suitable for Large-Scale Whole-Genome Genotyping and Long-Term DNA Banking Using Blood Samples

    Science.gov (United States)

    Psifidi, Androniki; Dovas, Chrysostomos I.; Bramis, Georgios; Lazou, Thomai; Russel, Claire L.; Arsenos, Georgios; Banos, Georgios

    2015-01-01

    Over the recent years, next generation sequencing and microarray technologies have revolutionized scientific research with their applications to high-throughput analysis of biological systems. Isolation of high quantities of pure, intact, double stranded, highly concentrated, not contaminated genomic DNA is prerequisite for successful and reliable large scale genotyping analysis. High quantities of pure DNA are also required for the creation of DNA-banks. In the present study, eleven different DNA extraction procedures, including phenol-chloroform, silica and magnetic beads based extractions, were examined to ascertain their relative effectiveness for extracting DNA from ovine blood samples. The quality and quantity of the differentially extracted DNA was subsequently assessed by spectrophotometric measurements, Qubit measurements, real-time PCR amplifications and gel electrophoresis. Processing time, intensity of labor and cost for each method were also evaluated. Results revealed significant differences among the eleven procedures and only four of the methods yielded satisfactory outputs. These four methods, comprising three modified silica based commercial kits (Modified Blood, Modified Tissue, Modified Dx kits) and an in-house developed magnetic beads based protocol, were most appropriate for extracting high quality and quantity DNA suitable for large-scale microarray genotyping and also for long-term DNA storage as demonstrated by their successful application to 600 individuals. PMID:25635817

  20. Comparison of eleven methods for genomic DNA extraction suitable for large-scale whole-genome genotyping and long-term DNA banking using blood samples.

    Science.gov (United States)

    Psifidi, Androniki; Dovas, Chrysostomos I; Bramis, Georgios; Lazou, Thomai; Russel, Claire L; Arsenos, Georgios; Banos, Georgios

    2015-01-01

    Over the recent years, next generation sequencing and microarray technologies have revolutionized scientific research with their applications to high-throughput analysis of biological systems. Isolation of high quantities of pure, intact, double stranded, highly concentrated, not contaminated genomic DNA is prerequisite for successful and reliable large scale genotyping analysis. High quantities of pure DNA are also required for the creation of DNA-banks. In the present study, eleven different DNA extraction procedures, including phenol-chloroform, silica and magnetic beads based extractions, were examined to ascertain their relative effectiveness for extracting DNA from ovine blood samples. The quality and quantity of the differentially extracted DNA was subsequently assessed by spectrophotometric measurements, Qubit measurements, real-time PCR amplifications and gel electrophoresis. Processing time, intensity of labor and cost for each method were also evaluated. Results revealed significant differences among the eleven procedures and only four of the methods yielded satisfactory outputs. These four methods, comprising three modified silica based commercial kits (Modified Blood, Modified Tissue, Modified Dx kits) and an in-house developed magnetic beads based protocol, were most appropriate for extracting high quality and quantity DNA suitable for large-scale microarray genotyping and also for long-term DNA storage as demonstrated by their successful application to 600 individuals.

  1. Comparison of eleven methods for genomic DNA extraction suitable for large-scale whole-genome genotyping and long-term DNA banking using blood samples.

    Directory of Open Access Journals (Sweden)

    Androniki Psifidi

    Full Text Available Over the recent years, next generation sequencing and microarray technologies have revolutionized scientific research with their applications to high-throughput analysis of biological systems. Isolation of high quantities of pure, intact, double stranded, highly concentrated, not contaminated genomic DNA is prerequisite for successful and reliable large scale genotyping analysis. High quantities of pure DNA are also required for the creation of DNA-banks. In the present study, eleven different DNA extraction procedures, including phenol-chloroform, silica and magnetic beads based extractions, were examined to ascertain their relative effectiveness for extracting DNA from ovine blood samples. The quality and quantity of the differentially extracted DNA was subsequently assessed by spectrophotometric measurements, Qubit measurements, real-time PCR amplifications and gel electrophoresis. Processing time, intensity of labor and cost for each method were also evaluated. Results revealed significant differences among the eleven procedures and only four of the methods yielded satisfactory outputs. These four methods, comprising three modified silica based commercial kits (Modified Blood, Modified Tissue, Modified Dx kits and an in-house developed magnetic beads based protocol, were most appropriate for extracting high quality and quantity DNA suitable for large-scale microarray genotyping and also for long-term DNA storage as demonstrated by their successful application to 600 individuals.

  2. Korpusbasert undervisning i fremmedspråkene: La elevens nysgjerrighet sette dagsorden

    Directory of Open Access Journals (Sweden)

    Margrete Dyvik Cardona

    2014-09-01

    Full Text Available Korpus er en type digitale språkressurser (maskinlesbare tekstsamlinger som er mye brukt i moderne lingvistikk som empirisk støtte for studiet av ulike språklige fenomener. Korpus kan med hell brukes i fremmedspråkundervisningen, men er frem til nå ikke i tilstrekkelig grad blitt tatt i bruk i norsk skole og høyere utdanning. I denne artikkelen gir vi en gjennomgang av eksisterende forskningslitteratur på feltet, med hovedvekt på bidrag fra det angloamerikanske språkområdet. Deretter går vi gjennom to korpus som er tilgjengelige for norske brukere, Norwegian-Spanish Parallel Corpus og Oslo Multilingual Corpus. Vi viser hvordan disse korpusene kan brukes i undervisningen av ulike språklige fenomener, fra vokabular til sosiolingvistiske fenomener. På grunnlag av eksisterende forskning på pedagogiske applikasjoner av korpus samt våre egne forslag til undervisningsopplegg er det grunn til å tro at bruk av korpus vil kunne være et verdifullt bidrag til fremmedspråkundervisningen i norske klasserom. Likevel finnes visse utfordringer som hindrer at korpus tas i bruk. Både mangel på tid, gruppestørrelser og teknologiske hindre kan stå i veien. Bruk av korpus i fremtidens klasserom er også nært knyttet til ulike trender, både innenfor teknologi og forskning. For det først blir datateknologi stadig mer tilgjengelig, parallelt med at elevenes og studentenes digitale kompetanse øker. Dette er fenomener som begge skulle tilsi økt bruk av korpus. Videre er det en sterk bevegelse for å åpne opp tilgang til forskningsdata og –ressurser (Open Access og denne bølgen kan også brukes til å åpne opp forskningsressurser, herunder korpus, for læringsformål. Til syvende og sist er spørsmålet om bruk av korpus i klasserommet imidlertid avhengig av en tettere dialog mellom lærere og korpuslingvister, både i lærerutdanningen så vel som gjennom faglig oppdatering underveis i yrkeslivet.

  3. Still not adult-like: lexical stress contrastivity in word productions of eight- to eleven-year-olds.

    Science.gov (United States)

    Arciuli, Joanne; Ballard, Kirrie J

    2017-09-01

    Lexical stress is the contrast between strong and weak syllables within words. Ballard et al. (2012) examined the amount of stress contrastivity across adjacent syllables in word productions of typically developing three- to seven-year-olds and adults. Here, eight- to eleven-year-olds are compared with the adults from Ballard et al. using acoustic measurements of relative contrast in duration, peak intensity, and peak fundamental frequency of the vowels within the initial two syllables of each word. While eight- to eleven-year-olds are closer to adult-like stress contrastivity than three- to seven-year-olds, they are not yet adult-like in terms of the intensity contrast for words beginning with a weak syllable.

  4. The amino acid sequences of eleven tryptic peptides of papaya mosaic virus protein by electron ionization mass spectrometry.

    Science.gov (United States)

    Parente, A; Short, M N; Self, R; Parsley, K R

    1982-04-01

    Eleven of the fourteen tryptic peptides of papaya mosaic virus protein have been sequenced by electron ionization mass spectrometry using chemical and enzymic hydrolyses and mixture analysis as required. Mid-chain cleavages of N-C bonds produced secondary ion series which allowed up to 16 residues to be sequenced without further hydrolysis. Mixture analysis on hydrolysis products enabled a 24 residue tryptic peptide to be sequenced from the data recorded in a single mass spectrum.

  5. Association between Maternal Depression Symptoms across the First Eleven Years of Their Child's Life and Subsequent Offspring Suicidal Ideation.

    Directory of Open Access Journals (Sweden)

    Gemma Hammerton

    Full Text Available Depression is common, especially in women of child-bearing age; prevalence estimates for this group range from 8% to 12%, and there is robust evidence that maternal depression is associated with mental health problems in offspring. Suicidal behaviour is a growing concern amongst young people and those exposed to maternal depression are likely to be especially at high risk. The aim of this study was to utilise a large, prospective population cohort to examine the relationship between depression symptom trajectories in mothers over the first eleven years of their child's life and subsequent adolescent suicidal ideation. An additional aim was to test if associations were explained by maternal suicide attempt and offspring depressive disorder. Data were utilised from a population-based birth cohort: the Avon Longitudinal Study of Parents and Children. Maternal depression symptoms were assessed repeatedly from pregnancy to child age 11 years. Offspring suicidal ideation was assessed at age 16 years. Using multiple imputation, data for 10,559 families were analysed. Using latent class growth analysis, five distinct classes of maternal depression symptoms were identified (minimal, mild, increasing, sub-threshold, chronic-severe. The prevalence of past-year suicidal ideation at age 16 years was 15% (95% CI: 14-17%. Compared to offspring of mothers with minimal symptoms, the greatest risk of suicidal ideation was found for offspring of mothers with chronic-severe symptoms [OR 3.04 (95% CI 2.19, 4.21], with evidence for smaller increases in risk of suicidal ideation in offspring of mothers with sub-threshold, increasing and mild symptoms. These associations were not fully accounted for by maternal suicide attempt or offspring depression diagnosis. Twenty-six percent of non-depressed offspring of mothers with chronic-severe depression symptoms reported suicidal ideation. Risk for suicidal ideation should be considered in young people whose mothers have a

  6. Association between Maternal Depression Symptoms across the First Eleven Years of Their Child's Life and Subsequent Offspring Suicidal Ideation.

    Science.gov (United States)

    Hammerton, Gemma; Mahedy, Liam; Mars, Becky; Harold, Gordon T; Thapar, Anita; Zammit, Stanley; Collishaw, Stephan

    2015-01-01

    Depression is common, especially in women of child-bearing age; prevalence estimates for this group range from 8% to 12%, and there is robust evidence that maternal depression is associated with mental health problems in offspring. Suicidal behaviour is a growing concern amongst young people and those exposed to maternal depression are likely to be especially at high risk. The aim of this study was to utilise a large, prospective population cohort to examine the relationship between depression symptom trajectories in mothers over the first eleven years of their child's life and subsequent adolescent suicidal ideation. An additional aim was to test if associations were explained by maternal suicide attempt and offspring depressive disorder. Data were utilised from a population-based birth cohort: the Avon Longitudinal Study of Parents and Children. Maternal depression symptoms were assessed repeatedly from pregnancy to child age 11 years. Offspring suicidal ideation was assessed at age 16 years. Using multiple imputation, data for 10,559 families were analysed. Using latent class growth analysis, five distinct classes of maternal depression symptoms were identified (minimal, mild, increasing, sub-threshold, chronic-severe). The prevalence of past-year suicidal ideation at age 16 years was 15% (95% CI: 14-17%). Compared to offspring of mothers with minimal symptoms, the greatest risk of suicidal ideation was found for offspring of mothers with chronic-severe symptoms [OR 3.04 (95% CI 2.19, 4.21)], with evidence for smaller increases in risk of suicidal ideation in offspring of mothers with sub-threshold, increasing and mild symptoms. These associations were not fully accounted for by maternal suicide attempt or offspring depression diagnosis. Twenty-six percent of non-depressed offspring of mothers with chronic-severe depression symptoms reported suicidal ideation. Risk for suicidal ideation should be considered in young people whose mothers have a history of

  7. Increased 5-hydroxymethylcytosine and Ten-eleven Translocation Protein Expression in Ultraviolet B-irradiated HaCaT Cells

    Science.gov (United States)

    Wang, Dan; Huang, Jin-Hua; Zeng, Qing-Hai; Gu, Can; Ding, Shu; Lu, Jian-Yun; Chen, Jing; Yang, Sheng-Bo

    2017-01-01

    Background: DNA hydroxymethylation refers to a chemical modification process in which 5-methylcytosine (5mC) is catalyzed to 5- hydroxymethylcytosine (5hmC) by ten-eleven translocation (TET) family proteins. Recent studies have revealed that aberrant TETs expression or 5hmC level may play important roles in the occurrence and development of various pathological and physiological processes including cancer and aging. This study aimed to explore the relation between aberrant DNA hydroxymethylation with skin photoaging and to investigate the levels of TETs, 5mC, and 5hmC expression 24 h after 40 mJ/cm2 and 80 mJ/cm2 doses of ultraviolet B (UVB) irradiation to HaCaT cells. Methods: To explore whether aberrant DNA hydroxymethylation is also related to skin photoaging, 40 mJ/cm2 and 80 mJ/cm2 doses of UVB were chosen to treat keratinocytes (HaCaT cells). After 24 h of UVB irradiation, 5mC and 5hmC levels were determined by immunohistochemistry (IHC) and immunofluorescence (IF), and at the same time, the expression levels of matrix metalloproteinase 1 (MMP-1) and TETs were assessed by reverse transcription-polymerase chain reaction or Western blot analysis. Results: After 40 mJ/cm2 and 80 mJ/cm2 doses of UVB exposure, both IHC and IF results showed that 5hmC levels increased significantly, while the 5mC levels did not exhibit significant changes in HaCaT cells, compared with HaCat cells without UVB exposure. Moreover, compared with HaCat cells without UVB exposure, the levels of TET1, TET2, and TET3 mRNA and protein expression were significantly upregulated (mRNA: P = 0.0022 and 0.0043 for TET1; all P expression increased dose dependently in 40 mJ/cm2 and 80 mJ/cm2 UVB-irradiated groups. Conclusion: UVB radiation could cause increased 5hmC and TET expression, which might become a novel biomarker in UVB-related skin aging. PMID:28229992

  8. Symptoms and health complaints and their association with perceived stress at university: survey of students at eleven faculties in Egypt.

    Science.gov (United States)

    El Ansari, Walid; Oskrochi, Reza; Labeeb, Shokria; Stock, Christiane

    2014-06-01

    This study examined the relationships between perceived stress and a range of self reported symptoms and health complaints in a representative sample of students at one university in Egypt. The data (3,271 students) was collected during the academic year 2009-2010 at eleven faculties at the university of Assiut city, Egypt. A self-administered questionnaire measured health complaints (22 symptoms) and Cohen's Perceived Stress Scale. Socio-demographic and lifestyle data were also collected. Factor analysis generated four groups of health complaints: psychological, circulatory/breathing, gastrointestinal, and pains/aches, and the internal consistency of each group of symptoms was computed using reliability analyses (Cronbach's alpha). Perceived stress was categorized into four levels based on quartiles. Multiple binomial or multinomial logistic regression analyses analysed the relationship between each of the four groups of symptoms and other students' general characteristics adjusted for the effect of all other groups of symptoms. The symptoms most often reported as having occurred sometimes/very often in the last 12 months were fatigue (85.3%), difficulties to concentrate (78.1%), headache (77.9%), and mood swings (74.5%), while nervousness/anxiety (63.2%) and sleep disorder (63.7%) affected many students. Multinominal logistic regression revealed a clear association and a linear trend between increasing level of stress and a higher frequency of psychological symptoms that remained significant after adjustment for other groups of symptoms. There were no associations between perceived stress and circulatory/breathing symptoms, gastrointestinal symptoms, or for pains/aches. Poor health was consistently associated with higher frequency of symptoms across all symptom groups except for gastrointestinal symptoms. Higher health awareness was associated with lower frequency of psychological and circulatory/breathing symptoms but not for the other two symptom groups. Better

  9. Vertical distribution and composition of weed seeds within the plough layer after eleven years of contrasting crop rotation and tillage schemes

    DEFF Research Database (Denmark)

    Scherner, Ananda; Melander, Bo; Kudsk, Per

    2016-01-01

    Tillage methods and crop rotation are probably the two most important cropping factors affecting weed communities, particularly when herbicide use is restricted. This study examined weed dynamics following eleven years of different tillage and crop rotation treatments. The aboveground grass weed...... in a more even distribution between the three layers. It is suggested that in cases where severe grass weed problems have built up in a non-inversion tillage system and where changes in crop rotation are ineffective or undesirable, inversion of the upper soil layer with the lower one could be considered...... by frequent cropping of winter cereals. The two non-inversion tillage treatments caused a strong stratification of weed seeds within the plough layer, with the majority of the seeds being accumulated in the upper soil layers, at 0–5 and 5–10 cm, and markedly less so in the 10–20 cm layer. Ploughing resulted...

  10. The E-pistolary Novel: Print Screens of Media-driven Thoughts in David Llewellyn’s Eleven

    Directory of Open Access Journals (Sweden)

    Oana Celia GHEORGHIU

    2014-12-01

    Full Text Available Contemporary literature seems to have reconciled the idea that everything valuable has already been said and done and, as such, has wilfully inscribed itself in a never-ending cycle of narratives about narratives, in a process of recycling and updating the past, which some love to name postmodernist. What is left at stake is simply the consumerist need to produce an oxymoronic ‘original copy’: to launch that piece of literature unseen and unheard of before on a crowded book market. A recipe for success seems to be the ability to combine the novelty of the architectural design – the formal innovation – with the thematisation of the present. It is precisely what the young Welsh novelist and scriptwriter, David Llewellyn, achieves with his debut novel, Eleven. In an attempt to translate the old into the new, Eleven is constructed following the design of the early modern epistolary novels, yet making use of a contemporary mode of writing: the email. Thematically, it is an exploration of patterns of individual thinking shaped by the media, against the background of an event with global consequences, which is, nevertheless, viewed from afar, without the inherent trauma so visible in American post-9/11 fiction. The present paper aims at analysing the construction of the novel, including the linguistic transformations it employs, and at accounting for the identitaryrevolt that transpires from the e mails exchanged between various character-narrators on an apparently ordinary day: September 11, 2001.

  11. Acquisition of a novel eleven amino acid insertion directly N-terminal to a tetrabasic cleavage site confers intracellular cleavage of an H7N7 influenza virus hemagglutinin

    Energy Technology Data Exchange (ETDEWEB)

    Hamilton, Brian S.; Sun, Xiangjie; Chung, Changik [Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca NY 14853 (United States); New York Center of Excellence for Influenza Research and Surveillance, University of Rochester Medical Center, Rochester NY 14627 (United States); Whittaker, Gary R., E-mail: grw7@cornell.edu [Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca NY 14853 (United States); New York Center of Excellence for Influenza Research and Surveillance, University of Rochester Medical Center, Rochester NY 14627 (United States)

    2012-12-05

    A critical feature of highly pathogenic avian influenza viruses (H5N1 and H7N7) is the efficient intracellular cleavage of the hemagglutinin (HA) protein. H7N7 viruses also exist in equine species, and a unique feature of the equine H7N7 HA is the presence of an eleven amino acid insertion directly N-terminal to a tetrabasic cleavage site. Here, we show that three histidine residues within the unique insertion of the equine H7N7 HA are essential for intracellular cleavage. An asparagine residue within the insertion-derived glycosylation site was also found to be essential for intracellular cleavage. The presence of the histidine residues also appear to be involved in triggering fusion, since mutation of the histidine residues resulted in a destabilizing effect. Importantly, the addition of a tetrabasic site and the eleven amino acid insertion conferred efficient intracellular cleavage to the HA of an H7N3 low pathogenicity avian influenza virus. Our studies show that acquisition of the eleven amino acid insertion offers an alternative mechanism for intracellular cleavage of influenza HA.

  12. Road and Street Centerlines, Separate street centerline files for eleven counties. Data is obtained from the counties., Published in 2007, NC Dept of Commerce - DCA.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — , was produced all or in part from Other information as of 2007. It is described as 'Separate street centerline files for eleven counties. Data is obtained from the...

  13. Benthic sediment data from eleven stations in the Mobile-Tensaw River Delta, Alabama on 17 June 1981 (NODC Accession 0118497)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Benthic sediment samples were collected from eleven stations in the Mobile-Tensaw River Delta on 17 June 1981. Samples were analyzed for particle size distribution...

  14. Constructing Practical Knowledge of Teaching: Eleven Newly Qualified Language Teachers' Discursive Agency

    Science.gov (United States)

    Ruohotie-Lyhty, Maria

    2011-01-01

    This paper explores the professional development of 11 newly qualified foreign language teachers. It draws on a qualitative longitudinal study conducted at the University of Jyvaskyla, Finland between 2002 and 2009. The paper concentrates on the personal side of teacher development by analysing participants' discourses concerning language…

  15. Eleven years' effect of conservation practices for temperate sandy loams: II. Soil pore characteristics

    DEFF Research Database (Denmark)

    Abdollahi, Lotfallah; Munkholm, Lars Juhl

    2017-01-01

    Conservation agriculture (CA) is regarded by many as a sustainable intensification strategy. Minimal soil disturbance in combination with residue retention are important CA components. This study examined the long-term effects of crop rotation, residue retention, and tillage on soil pore characte......Conservation agriculture (CA) is regarded by many as a sustainable intensification strategy. Minimal soil disturbance in combination with residue retention are important CA components. This study examined the long-term effects of crop rotation, residue retention, and tillage on soil pore......, the volume of pores > 30 μm was more than 0.03 m3 m-3 larger for MP than for D in spring 2014 at the 4- to 8-cm depth. At the 18- to 27-cm depth, direct drilling resulted in a better air permeability and pore continuity index (e.g., air permeability of 18.2 and 11.2 mm2 for D and MP, respectively at −10 k...

  16. Stimulation of flower nectar replenishment by removal: A survey of eleven animal-pollinated plant species

    Directory of Open Access Journals (Sweden)

    Elaine Y Luo

    2014-02-01

    Full Text Available Understanding the interaction between reward-seeking flower feeding animals and plants requires consideration of the dynamic nature of nectar secretion. Studies on several plants suggest that nectar secretion may increase in response to its removal, but it is not clear whether the phenomenon is widespread. We determined whether 11 species of Colorado mountain wildflowers showed removal-enhanced nectar replenishment (RENR. We measured floral phenology, nectar volumes, rate of replenishment, and compared the cumulative nectar produced following five hourly removals with that accumulated after five hours. Nectar replenishment occurred rapidly, within minutes; statistically significant RENR was observed in 9 of our 11 study species, with the strongest effects in bee-pollinated species. We discuss the implications of RENR in plant species on the measurement of nectar, the adaptive advantage of RENR, and the energetic costs of RENR.

  17. Hvordan kan valgfaget friluftsliv påvirke elevenes motivasjon og læring?

    OpenAIRE

    Slyngstad, Petter

    2013-01-01

    The main purpose of this reseach was to identify optional subject outdoors as a learning arena. My main issue has been: How can the optional subject outdoors affect students' motivation and learning? This has been an empirical, qualitative study where different methods have been used. The empirical material presented through student reports, field observations and interviews of a student group and teacher. Electives signaling the freedom for students to choose a subject based on their own ...

  18. Prevalence of self-reported allergic rhinitis in eleven major cities in china.

    Science.gov (United States)

    Zhang, Luo; Han, Demin; Huang, Dan; Wu, Yangfeng; Dong, Zhen; Xu, Geng; Kong, Weijia; Bachert, Claus

    2009-01-01

    Allergic rhinitis (AR) is a common disease and its prevalence is increasing worldwide. Data on the current prevalence of AR in China, one of the biggest countries in the world, with a population of around 1.3 billion citizens, are scarce. The aim of this study was to investigate the prevalence of self-reported AR in Chinese citizens. In a cross-sectional, population-based study, telephone interviews were conducted in 11 major cities in China after sampling target telephone numbers through the approach of random digital dialing. The questions for the telephone interviews were based on validated questionnaires. A total of 38,203 telephone interviews were conducted from September 2004 to May 2005. The response rate was 63.7%. After adjustment for age and gender, the self-reported prevalence of AR was lowest in Beijing (8.7%) and highest in Urumqi (24.1%). Among the subjects with self-reported AR, 25.6% were diagnosed with persistent AR and 74.4% suffered from intermittent AR. Less than half of the subjects with self-reported AR had presented at a health clinic. In 37.3% AR had previously been diagnosed by physicians, and 33.1% of subjects with self-reported AR had been treated. Comorbidities reported were asthma (9.2%), rhinosinusitis (13.3%) and atopic dermatitis (16.4%). This study demonstrates that the self-reported prevalence of AR in 11 cities across Mainland China has wide variations, ranging from 20%; 26% of the self-reported AR subjects were classified as suffering from persistent AR. 2008 S. Karger AG, Basel.

  19. A comparison of two antismoking interventions among pregnant women in eleven private primary care practices.

    Science.gov (United States)

    Messimer, S R; Hickner, J M; Henry, R C

    1989-03-01

    Despite the dangers of smoking during pregnancy having been widely publicized, few studies have actually examined the effectiveness of antismoking interventions among pregnant women in the private primary care obstetric setting. A randomized experimental study involving 24 private physicians and 109 pregnant smokers was conducted comparing the American Lung Association's Because You Love Your Baby smoking intervention (ALA) to a standard-of-care protocol (non-ALA). The non-ALA protocol was based upon the smoking interventions that study physicians said they commonly used among pregnant women. Self-reported smoking rates were obtained by questionnaire at the first prenatal visit, at 32 to 36 weeks' gestation, and at the six-week postpartum visit. By the time of the first prenatal visit, both groups reduced by half the number of cigarettes smoked. By 32 to 36 weeks, the groups decreased the daily average by an additional 2.3 (ALA) and 1.8 (non-ALA) cigarettes, a nonsignificant difference between the groups. Fifteen (28 percent) of the ALA group compared with 9 (16 percent) of the non-ALA group reported quitting at the 32- to 36-week visit (P = .10). Only 9 percent of the ALA group and 10 percent of the non-ALA were nonsmokers at the postpartum visit. Pregnancy alone is a powerful motivator for women to decrease their smoking. Although the difference between the ALA and non-ALA protocols did not attain statistical significance, the percentage of those who quit was comparable to the results obtained in other controlled trials. The ALA Because You Love Your Baby protocol should be used until more effective methods are available.

  20. Eleven X chromosome breakpoints associated with premature ovarian failure (POF) map to a 15-Mb YAC contig spanning Xq21.

    Science.gov (United States)

    Sala, C; Arrigo, G; Torri, G; Martinazzi, F; Riva, P; Larizza, L; Philippe, C; Jonveaux, P; Sloan, F; Labella, T; Toniolo, D

    1997-02-15

    Eleven balanced X-autosome translocations associated with premature ovarian failure (POF) were mapped to a YAC contig spanning most of Xq21 and constructed between the DXS223 and DXS1171 loci. The contig corresponds to a genomic region of about 15 Mb and contains the whole X-Y homologous region. The most proximal and most distal breakpoints associated with POF were mapped 15 Mb apart. The remaining breakpoints were localized along this large region, in the X-specific and in the X-Y homologous region. Four of the YACs contained two breakpoints in the same or in flanking STS intervals. Our results confirm the cytological findings and suggest that a minimum number of eight different genes in Xq21 may be involved with ovary development. Interruption of such loci could be the cause of POF.

  1. In vivo allergenic activities of eleven purified members of a major allergen family from wheat and barley flour.

    Science.gov (United States)

    Armentia, A; Sanchez-Monge, R; Gomez, L; Barber, D; Salcedo, G

    1993-05-01

    Eleven purified members of the alpha-amylase/trypsin inhibitor family from wheat and barley that showed very different IgE-binding capacities when previously assayed in vitro, were used in double blind in vivo diagnostic tests to further evaluate their allergenic activity. These tests were carried out in 31 patients who showed allergic sensitization to wheat flour as verified by skin test, RAST and challenge test. The three members of the protein family with highest IgE binding in vitro (the glycosylated subunits of tetrameric alpha-amylase inhibitors CM16* from wheat and CMb* from barley, and the barley monomeric inhibitor BMAI-1) were found to be the strongest allergens as indicated by skin sensitivity in prick tests.

  2. Anisotropic seismic-waveform inversion: Application to a seismic velocity model from Eleven-Mile Canyon in Nevada

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Yu [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Gao, Kai [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Huang, Lianjie [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Sabin, Andrew [Geothermal Program Office, China Lake, CA (United States)

    2016-03-31

    Accurate imaging and characterization of fracture zones is crucial for geothermal energy exploration. Aligned fractures within fracture zones behave as anisotropic media for seismic-wave propagation. The anisotropic properties in fracture zones introduce extra difficulties for seismic imaging and waveform inversion. We have recently developed a new anisotropic elastic-waveform inversion method using a modified total-variation regularization scheme and a wave-energy-base preconditioning technique. Our new inversion method uses the parameterization of elasticity constants to describe anisotropic media, and hence it can properly handle arbitrary anisotropy. We apply our new inversion method to a seismic velocity model along a 2D-line seismic data acquired at Eleven-Mile Canyon located at the Southern Dixie Valley in Nevada for geothermal energy exploration. Our inversion results show that anisotropic elastic-waveform inversion has potential to reconstruct subsurface anisotropic elastic parameters for imaging and characterization of fracture zones.

  3. [Food quality and nutritional status in university students of eleven Chilean regions].

    Science.gov (United States)

    Ratner, Rinat G; Hernández, Paulina J; Martel, Jorge A; Atalah, Eduardo S

    2012-12-01

    The Chilean population has inadequate lifestyles and high prevalence of chronic diseases. To analyze eating behaviors, nutritional status and history of previous diseases, in students of higher education. Cross-sectional study in students of 54 higher education centers across the country. They answered a survey about dietary habits, physical activity, smoking, previous diseases and opinion of their nutritional condition. Weight and height were measured under standardized conditions and nutritional status classified according to body mass index. We studied 6,823 students aged 17 to 29 years. Forty seven percent did not have breakfast and 35% did not have lunch every day. A low proportion had a daily consumption of vegetables (51.2%), fruits (39.4%) and dairy products (57.5%). There was a high frequency of soft drinks, chips, cakes and sweets consumption. Seventy six percent were sedentary, 40.3% smokers and 27.4% overweight or obese. The latter had a significantly higher frequency of diabetes, hypertension and hypercholesterolemia. There was a poor agreement between actual nutritional status and self-perception, especially in males (Kappa index 0.38). Recipients of a food scholarship provided by the Ministry of Education ate lunch usually with a higher frequency (p < 0.05). A high prevalence of inadequate eating and physical activity patterns in these young subjects with good educational level was observed. The food scholarship has some positive effects, although differences in socioeconomic levels limited comparisons.

  4. Inequalities in mortality in small areas of eleven Spanish cities (the multicenter MEDEA project).

    Science.gov (United States)

    Borrell, Carme; Marí-Dell'olmo, Marc; Serral, Gemma; Martínez-Beneito, Miguel; Gotsens, Mercè

    2010-07-01

    The objectives of this study are to identify inequalities in mortality among census tracts of 11 Spanish cities in the period 1996-2003 and to analyse the relationship between these geographical inequalities and socioeconomic deprivation. It is a cross-sectional ecological study where the units of analysis are census tracts. We obtained an index of socioeconomic deprivation and estimated SMR by each census tract using hierarchical Bayesian models which take into account the spatial structure. In the majority of the cities geographical patterns in total mortality were found in both sexes, which were similar to those for the index of socioeconomic deprivation. Among men, four specific causes of death (lung cancer, ischemic heart diseases, respiratory diseases and cirrhosis) were positively associated with deprivation in the majority of cities. Among women the specific causes diabetes and cirrhosis were positively associated, while lung cancer was negatively associated with deprivation. The excess of mortality related with deprivation was 59,445 deaths among men and 23,292 among women. These results highlight the importance of intra-urban inequalities in health. 2010 Elsevier Ltd. All rights reserved.

  5. Mid-term behaviour of cemented titanium stems: A seven to eleven year clinical.

    Science.gov (United States)

    Vlatis, G; Georgiades, G; Magnissalis, E A; Hartofilakidis, G

    A controversy exists regarding the results of cemented Ti-alloy femoral stems. Although most authors reported unfavourable results, there is no clear evidence of the exact reason for the increased failure rate. We studied 35 arthroplasties in 30 patients with a mean age at the time of surgery of 49.7 years (range 27 to 67 years). In most of them (23 hips) the pre-operative diagnosis was hip dysplasia or dislocation. The femoral component used in this study was the Optifix stem. Survival analysis showed a cumulative rate of success at nine years of 90.4% (15.3) with 25.5 femoral components remaining at risk. Three femoral components were retrieved during revision surgery: due to fatigue fracture, fracture of the femur and aseptic loosening respectively. Given that most publications refer to different designs of stems we presume that the problem could be focused on the design rather than the material or the method of fixation. Further information is necessary before Ti-alloy stems fixed with cement are withdrawn from use. (Hip International 2005; 15: 12-20).

  6. Task IV: Development of Circumferential Inlet Distortion through a Representative Eleven Stage High-speed Axial Compressor

    Science.gov (United States)

    Tan, Choon-Sooi; Suder, Kenneth (Technical Monitor)

    2003-01-01

    The concepts and the procedure developed in Task I and Task III were used to determine the response of an eleven-stage high-speed compressor to an inlet distortion of 180 deg. circumferential extent for contrasting against its performance under uniform inlet flow. Using the computed results at the inlet to and outlet of the compressor, the computed total pressure ratio and efficiency for the clean condition are determined to be 14.22 and 76.9 percent respectively. As for the distorted case, these are determined to be 10.35 and 71.8 percent respectively, showing deterioration 76.9 percent vs 71.8 percent). The physical consistency of the computed flow field was assessed as a means of demonstrating the applicability and utility of the body force representation for inlet distortion computations. Specifically the computed evolution of the distorted pattern in static pressure and total pressure from compressor inlet to exit is examined. For the eleven-stage compressor examined here, the deterioration in performance has been found to be particularly severe in the last 2 stages. This suggests that the last two stages could be redesigned to alleviate the observed deterioration thus making the compressor performance insensitive to circumferential inlet distortion. This can potentially be accomplished by first determining what should the body force distribution of the last two stages should be to achieve minimal or no deterioration in performance in the last two stages. One can then in principle proceed to determine the blade design to yield such a body force distribution.

  7. Computer Vision Syndrome in Eleven to Eighteen-Year-Old Students in Qazvin

    Directory of Open Access Journals (Sweden)

    Khalaj

    2015-08-01

    Full Text Available Background Prolonged use of computers can lead to complications such as eye strain, eye and head aches, double and blurred vision, tired eyes, irritation, burning and itching eyes, eye redness, light sensitivity, dry eyes, muscle strains, and other problems. Objectives The aim of the present study was to evaluate visual problems and major symptoms, and their associations among computer users, aged between 11 and 18 years old, residing in the Qazvin city of Iran, during year 2010. Patients and Methods This cross-sectional study was done on 642 secondary to pre university students who had referred to the eye clinic of Buali hospital of Qazvin during year 2013. A questionnaire consisting of demographic information and 26 questions on visual effects of the computer was used to gather information. Participants answered all questions and then underwent complete eye examinations and in some cases cycloplegic refraction. Visual acuity (VA was measured with a logMAR in six meters. Refraction errors were determined using an auto refractometer (Potece and Heine retinoscope. The collected data was then analyzed using the SPSS statistical software. Results The results of this study indicated that 63.86% of the subjects had refractive errors. Refractive errors were significantly different in children of different genders (P < 0.05. The most common complaints associated with the continuous use of computers were eyestrain, eye pain, eye redness, headache, and blurred vision. The most prevalent (81.8% eye-related problem in computer users was eyestrain and the least prevalent was dry eyes (7.84%. In order to reduce computer related problems 54.2% of the participants suggested taking enough rest, 37.9% recommended use of computers only for necessary tasks, while 24.4% and 19.1% suggested the use of monitor shields and proper working distance, respectively. Conclusions Our findings revealed that using computers for prolonged periods of time can lead to eye

  8. Comparative chloroplast genomes of eleven Schima (Theaceae) species: Insights into DNA barcoding and phylogeny.

    Science.gov (United States)

    Yu, Xiang-Qin; Drew, Bryan T; Yang, Jun-Bo; Gao, Lian-Ming; Li, De-Zhu

    2017-01-01

    Schima is an ecologically and economically important woody genus in tea family (Theaceae). Unresolved species delimitations and phylogenetic relationships within Schima limit our understanding of the genus and hinder utilization of the genus for economic purposes. In the present study, we conducted comparative analysis among the complete chloroplast (cp) genomes of 11 Schima species. Our results indicate that Schima cp genomes possess a typical quadripartite structure, with conserved genomic structure and gene order. The size of the Schima cp genome is about 157 kilo base pairs (kb). They consistently encode 114 unique genes, including 80 protein-coding genes, 30 tRNAs, and 4 rRNAs, with 17 duplicated in the inverted repeat (IR). These cp genomes are highly conserved and do not show obvious expansion or contraction of the IR region. The percent variability of the 68 coding and 93 noncoding (>150 bp) fragments is consistently less than 3%. The seven most widely touted DNA barcode regions as well as one promising barcode candidate showed low sequence divergence. Eight mutational hotspots were identified from the 11 cp genomes. These hotspots may potentially be useful as specific DNA barcodes for species identification of Schima. The 58 cpSSR loci reported here are complementary to the microsatellite markers identified from the nuclear genome, and will be leveraged for further population-level studies. Phylogenetic relationships among the 11 Schima species were resolved with strong support based on the cp genome data set, which corresponds well with the species distribution pattern. The data presented here will serve as a foundation to facilitate species identification, DNA barcoding and phylogenetic reconstructions for future exploration of Schima.

  9. Childhood chronic inflammatory demyelinating polyradiculoneuropathy: combined analysis of a large cohort and eleven published series.

    Science.gov (United States)

    McMillan, Hugh J; Kang, Peter B; Jones, H Royden; Darras, Basil T

    2013-02-01

    The clinical presentation, disease course, response to treatment, and long-term outcome of thirty childhood chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) patients are presented representing the largest cohort reported to date. Most children (60%) presented with chronic (>8-weeks) symptom-onset while a smaller proportion showed sub-acute (4-8 weeks) or acute (''GBS-like''; CIDP series providing a comprehensive review of 143 childhood CIDP cases. The combined initial or first-line treatment response across all studies was favourable for IVIG (79% patients) and corticosteroids (84% patients). Response to first-line plasma exchange was poor (only 14% patients improved) although it may offer some transient or partial benefit as an adjuvant or temporary therapy for selected patients. The combined long-term outcome of our cohort and the literature reveals a favourable prognosis for most patients. The combined modified Rankin scale decreased from 3.7 (at presentation) to 0.7 (at last follow-up). This review provides important data pertaining to clinical course, treatment response and long-term outcome of this relatively uncommon paediatric autoimmune disease.

  10. Classical integrable systems and soliton equations related to eleven-vertex R-matrix

    Directory of Open Access Journals (Sweden)

    A. Levin

    2014-10-01

    Full Text Available In our recent paper we suggested a natural construction of the classical relativistic integrable tops in terms of the quantum R-matrices. Here we study the simplest case – the 11-vertex R-matrix and related gl2 rational models. The corresponding top is equivalent to the 2-body Ruijsenaars–Schneider (RS or the 2-body Calogero–Moser (CM model depending on its description. We give different descriptions of the integrable tops and use them as building blocks for construction of more complicated integrable systems such as Gaudin models and classical spin chains (periodic and with boundaries. The known relation between the top and CM (or RS models allows to rewrite the Gaudin models (or the spin chains in the canonical variables. Then they assume the form of n-particle integrable systems with 2n constants. We also describe the generalization of the top to 1+1 field theories. It allows us to get the Landau–Lifshitz type equation. The latter can be treated as non-trivial deformation of the classical continuous Heisenberg model. In a similar way the deformation of the principal chiral model is described.

  11. Classical integrable systems and soliton equations related to eleven-vertex R-matrix

    Energy Technology Data Exchange (ETDEWEB)

    Levin, A., E-mail: alevin@hse.ru [NRU HSE, Department of Mathematics, Myasnitskaya str. 20, Moscow, 101000 (Russian Federation); ITEP, B. Cheremushkinskaya str. 25, Moscow, 117218 (Russian Federation); Olshanetsky, M., E-mail: olshanet@itep.ru [ITEP, B. Cheremushkinskaya str. 25, Moscow, 117218 (Russian Federation); MIPT, Institutskii per. 9, Dolgoprudny, Moscow Region, 141700 (Russian Federation); Zotov, A., E-mail: zotov@mi.ras.ru [Steklov Mathematical Institute RAS, Gubkina str. 8, Moscow, 119991 (Russian Federation); ITEP, B. Cheremushkinskaya str. 25, Moscow, 117218 (Russian Federation); MIPT, Institutskii per. 9, Dolgoprudny, Moscow Region, 141700 (Russian Federation)

    2014-10-15

    In our recent paper we suggested a natural construction of the classical relativistic integrable tops in terms of the quantum R-matrices. Here we study the simplest case – the 11-vertex R-matrix and related gl{sub 2} rational models. The corresponding top is equivalent to the 2-body Ruijsenaars–Schneider (RS) or the 2-body Calogero–Moser (CM) model depending on its description. We give different descriptions of the integrable tops and use them as building blocks for construction of more complicated integrable systems such as Gaudin models and classical spin chains (periodic and with boundaries). The known relation between the top and CM (or RS) models allows to rewrite the Gaudin models (or the spin chains) in the canonical variables. Then they assume the form of n-particle integrable systems with 2n constants. We also describe the generalization of the top to 1+1 field theories. It allows us to get the Landau–Lifshitz type equation. The latter can be treated as non-trivial deformation of the classical continuous Heisenberg model. In a similar way the deformation of the principal chiral model is described.

  12. Classical integrable systems and soliton equations related to eleven-vertex R-matrix

    Science.gov (United States)

    Levin, A.; Olshanetsky, M.; Zotov, A.

    2014-10-01

    In our recent paper we suggested a natural construction of the classical relativistic integrable tops in terms of the quantum R-matrices. Here we study the simplest case - the 11-vertex R-matrix and related gl2 rational models. The corresponding top is equivalent to the 2-body Ruijsenaars-Schneider (RS) or the 2-body Calogero-Moser (CM) model depending on its description. We give different descriptions of the integrable tops and use them as building blocks for construction of more complicated integrable systems such as Gaudin models and classical spin chains (periodic and with boundaries). The known relation between the top and CM (or RS) models allows to rewrite the Gaudin models (or the spin chains) in the canonical variables. Then they assume the form of n-particle integrable systems with 2n constants. We also describe the generalization of the top to 1+1 field theories. It allows us to get the Landau-Lifshitz type equation. The latter can be treated as non-trivial deformation of the classical continuous Heisenberg model. In a similar way the deformation of the principal chiral model is described.

  13. Classical integrable systems and soliton equations related to eleven-vertex R-matrix

    CERN Document Server

    Levin, A; Zotov, A

    2014-01-01

    In our recent paper we suggested a natural construction of the classical relativistic integrable tops in terms of the quantum $R$-matrices. Here we study the simplest case -- the 11-vertex $R$-matrix and related ${\\rm gl}_2$ rational models. The corresponding top is equivalent to the 2-body Ruijsenaars-Schneider (RS) or the 2-body Calogero-Moser (CM) model depending on its description. We give different descriptions of the integrable tops and use them as building blocks for construction of more complicated integrable systems such as Gaudin models and classical spin chains (periodic and with boundaries). The known relation between the top and CM (or RS) models allows to re-write the Gaudin models (or the spin chains) in the canonical variables. Then they assume the form of $n$-particle integrable systems with $2n$ constants. We also describe the generalization of the top to 1+1 field theories. It allows us to get the Landau-Lifshitz type equation. The latter can be treated as non-trivial deformation of the cla...

  14. Eleven years of recovery dynamic after experimental burning and cutting in two Cistus communities

    Science.gov (United States)

    Tárrega, Reyes; Luis-Calabuig, Estanislao; Valbuena, Luz

    2001-12-01

    Recovery after cutting and burning in two series of experimental shrubland plots dominated by Cistus laurifolius and Cistus ladanifer, respectively, was studied over 11 years. The two communities tend to recover by an autosuccession process after disturbances, with Cistus species being dominant from the first or second year. The greatest diversity is recorded in the first few years after the disturbances, with higher species richness, basically herbaceous ones, and lower dominance effect. Cover by woody species tends to increase but from the fourth year the differences are not significant. The highest herbaceous cover is after one year and the peak is more marked in the cut plots. Herbaceous species cover decreases afterwards and there are small changes in the different years but without clear trends. When all the samplings are compared by a TWINSPAN, the first division separates both communities and the second division the initial and the final phases from each community. The separation between cut and burnt plots is only observed in the final phases.

  15. Anticipatory reaching of seven- to eleven-month-old infants in occlusion situations.

    Science.gov (United States)

    van Wermeskerken, Margot; van der Kamp, John; Te Velde, Arenda F; Valero-Garcia, Ana V; Hoozemans, Marco J M; Savelsbergh, Geert J P

    2011-02-01

    The present study examined 7- to 11-month-old infants' anticipatory and reactive reaching for temporarily occluded objects. Infants were presented with laterally approaching objects that moved at different velocities (10, 20, and 40 cm/s) in different occlusion situations (no-, 20 cm-, and 40 cm-occlusion), resulting in occlusion durations ranging between 0 and 4s. Results show that except for object velocity and occlusion distance, occlusion duration was a critical constraint for infants' reaching behaviors. We found that the older infants reached more often, but that an increase in occlusion duration resulted in a decline in reaching frequency that was similar across age groups. Anticipatory reaching declined with increasing occlusion duration, but the adverse effects for longer occlusion durations diminished with age. It is concluded that with increasing age infants are able to retain and use information to guide reaching movements over longer periods of non-visibility, providing support for the graded representation hypothesis (Jonsson & von Hofsten, 2003) and the two-visual systems model (Milner & Goodale, 1995). Copyright © 2010 Elsevier Inc. All rights reserved.

  16. Anti-inflammatory activities of eleven Centaurea species occurring in the Carpathian Basin.

    Science.gov (United States)

    Csupor, Dezső; Widowitz, Ute; Blazsó, Gábor; Laczkó-Zöld, Eszter; Tatsimo, Joel S N; Balogh, Agnes; Boros, Klára; Dankó, Balázs; Bauer, Rudolf; Hohmann, Judit

    2013-04-01

    Our study aimed at the identification of anti-inflammatory activities of different fractions of C. sadleriana extract after per os administration in rats, the identification of the active compounds of the plant and the investigation of the in vitro anti-inflammatory activities of Centaurea species native to or cultivated in the Carpathian Basin. The aerial parts of Centaurea sadleriana Janka have been used in Hungarian folk medicine to treat the wounds of sheep. Methanol extract of C. sadleriana was fractioned by solvent-solvent partitioning. The n-hexane fraction was further fractionated and the anti-inflammatory activities of certain subfractions were confirmed in vivo in rats. The n-hexane and chloroform fraction of the methanol extract of C. sadleriana exhibited remarkable COX-1 and COX-2 inhibiting effects in vitro. Chromatographic separation of the fractions led to the identification of the active subfractions and 11 compounds (α-linolenic acid, γ-linolenic acid, stigmasterol, β-sitosterol, campesterol, vanillin, pectolinarigenin, salvigenin, hispidulin, chrysoeriol and apigenin). The in vitro screening for anti-inflammatory activities of further Centaurea species occurring in the Carpathian Basin (C. adjarica, C. bracteata, C. cataonica, C. cynaroides, C. dealbata, C. indurata, C. macrocephala, C. melitensis, C. nigrescens, C. ruthenica) revealed considerable COX-1 and COX-2 inhibitory activities. Because C. sadleriana is an endangered species native only to the Carpathian Basin, the investigation of more prevalent species is reasonable. Copyright © 2012 John Wiley & Sons, Ltd.

  17. Eleven years of management of children with intestinal failure and not candidates for intestinal transplantation

    Directory of Open Access Journals (Sweden)

    MI Spagnuolo

    2010-09-01

    Full Text Available MI Spagnuolo, MP Cicalese, E Bruzzese, MA Caiazzo, S Di Caro, V Squeglia, A GuarinoDepartment of Paediatrics, University Federico II, Naples, ItalyBackground: Children with intestinal failure need parenteral nutrition to survive, and the only alternative is intestinal transplantation which still entails high mortality. The aim of this study was to compare the outcomes in candidates and noncandidates for intestinal transplantation, and to compare the outcomes with and without transplant surgery.Patients and methods: The clinical records of children admitted to hospital from 1997 to 2008 because of intestinal failure were reviewed for etiology of intestinal failure, age at start of parenteral nutrition, duration of parenteral nutrition, indications for intestinal transplantation, and outcome.Results: Thirty-four children were enrolled. Median age at start of parenteral nutrition was 13.1 (median 20.7 months. There was no difference in survival rate between candidates and noncandidates for intestinal transplantation. Survival was significantly higher in candidates who did not undergo intestinal transplantation than in children who underwent intestinal transplantation (P < 0.001.Conclusion: Candidates for intestinal transplantation who did not undergo transplant surgery had a better outcome than children who underwent transplant surgery.Keywords: intestinal transplantation, intestinal failure, parenteral nutrition, children

  18. Simultaneous determination of eleven preservatives in cosmetics by micellar electrokinetic chromatography.

    Science.gov (United States)

    Wang, Ping; Ding, Xiaojing; Li, Yun; Yang, Yuanyuan

    2012-01-01

    A new method for the simultaneous quantitation of 11 preservatives-imidazolidinyl urea, benzyl alcohol, dehydroacetic acid, sorbic acid, phenoxyethanol, benzoic acid, salicylic acid, and four parabens (methyl, ethyl, propyl, and butyl)-in cosmetics by micellar electrokinetic capillary chromatography was established and validated. The separation was performed using an uncoated fused-silica capillary (50 pm id x 60.2 cm, effective length 50 cm) with a running buffer consisting of 15 mmol/L sodium tetraborate, 60 mmol/L boric acid, and 100 mmol/L sodium dodecyl sulfate. A 1:10 dilution of the running buffer was used as the sample buffer to extract the cosmetic samples. The key factors, such as the concentration and pH of the running and sample buffers, which influence quantitative analysis of the above 11 preservatives in cosmetic samples, were investigated in detail. The linear ranges of the calibration curves for imidazolidinyl urea and the other 10 preservatives were 50-1000 and 10-200 mg/L, respectively. The correlation coefficients of the standard curves were all higher than 0.999. The recoveries at the concentrations studied ranged from 93.0 to 102.7%. RSDs were all less than 5%. The new method with simple sample pretreatment met the needs for routine analysis of the 11 preservatives in cosmetics.

  19. Variation in palatability and biochemical traits within and among eleven beef muscles.

    Science.gov (United States)

    Rhee, M S; Wheeler, T L; Shackelford, S D; Koohmaraie, M

    2004-02-01

    The objective of this study was to determine the extent of variation in, and relationships among, biochemical and palatability traits within and among 11 major beef muscles. Longissimus thoracis et lumborum (LD), psoas major (PM), gluteus medius (GM), semimembranosus (SM), adductor (AD), biceps femoris (BF), semitendinosus (ST), rectus femoris (RF), triceps brachii (TB), infraspinatus (IS), and supraspinatus (SS) from one side of 31 Charolais x MARC III steer carcasses were vacuum-packaged, stored at 2 degrees C until 14 d postmortem, and then frozen at -30 degrees C. The 2.54-cm-thick steaks were obtained from two or three locations within muscles in order to assess biochemical traits and Warner-Bratzler shear force, and from near the center for sensory trait evaluation. The PM was most tender and was followed by IS in both shear force and tenderness rating (P muscles were not ranked the same by shear force and tenderness rating. The BF had the lowest (P muscle) than muscles from the chuck and round (5.9 to 9.0 mg/g), except for the AD (4.9 mg/g). Desmin proteolysis was highest (P 2.1 microm), whereas the GM had the shortest (P muscles, tenderness rating was highly correlated (r > 0.60) with shear force, connective tissue rating, sarcomere length, and collagen content. Within a muscle, correlations among all traits were generally highest in LD and lowest in AD. Within muscle, location effects were detected (P muscles except SS and AD). There is a large amount of variation within and among muscles for tenderness traits and tenderness-related biochemical traits. These results increase our understanding of the sources of variation in tenderness in different muscles and provide a basis for the development of muscle-specific strategies for improving the quality and value of muscles.

  20. Lysosomal lipase deficiency: molecular characterization of eleven patients with Wolman or cholesteryl ester storage disease.

    Science.gov (United States)

    Fasano, Tommaso; Pisciotta, Livia; Bocchi, Letizia; Guardamagna, Ornella; Assandro, Paola; Rabacchi, Claudio; Zanoni, Paolo; Filocamo, Mirella; Bertolini, Stefano; Calandra, Sebastiano

    2012-03-01

    Wolman Disease (WD) and cholesteryl ester storage disease (CESD) represent two distinct phenotypes of the same recessive disorder caused by the complete or partial deficiency of lysosomal acidic lipase (LAL), respectively. LAL, encoded by the LIPA gene, hydrolyzes cholesteryl esters derived from cell internalization of plasma lipoproteins. WD is a rapidly progressive and lethal disease characterized by intestinal malabsorption, hepatic and adrenal failure. CESD is characterized by hepatic fibrosis, hyperlipidemia and accelerated atherosclerosis. Aim of the study was the identification of LIPA mutations in three WD and eight CESD patients. The WD patients, all deceased before the first year of age, were homozygous for two novel mutations (c.299+1G>A and c.419G>A) or a mutation (c.796G>T) previously reported as compound heterozygosity in a CESD patient. The two mutations (c.419G>A and c.796G>T) resulting in truncated proteins (p.W140* and p.G266*) and the splicing mutation (c.229+1G>A) were associated with undetectable levels of LIPA mRNA in fibroblasts. All eight CESD patients carried the common mutation c.894G>A known to result not only in a major non-functional transcript with the skipping of exon 8 (p.S275_Q298del), but also in a minor normally spliced transcript producing 5-10% residual LAL activity. The c.894G>A mutation was found in homozygosity in four patients and, as compound heterozygosity, in association with a known (p.H295Y and p.G342R) or a novel (p.W140*) mutation in four other CESD patients. Segregation analysis performed in all patients harboring c.895G>A showed its occurrence on the same haplotype suggesting a common founder ancestor. The other WD and CESD mutations were associated with different haplotypes.

  1. Respirable crystalline silica exposures during asphalt pavement milling at eleven highway construction sites.

    Science.gov (United States)

    Hammond, Duane R; Shulman, Stanley A; Echt, Alan S

    2016-07-01

    Asphalt pavement milling machines use a rotating cutter drum to remove the deteriorated road surface for recycling. The removal of the road surface has the potential to release respirable crystalline silica, to which workers can be exposed. This article describes an evaluation of respirable crystalline silica exposures to the operator and ground worker from two different half-lane and larger asphalt pavement milling machines that had ventilation dust controls and water-sprays designed and installed by the manufacturers. Manufacturer A completed milling for 11 days at 4 highway construction sites in Wisconsin, and Manufacturer B completed milling for 10 days at 7 highway construction sites in Indiana. To evaluate the dust controls, full-shift personal breathing zone air samples were collected from an operator and ground worker during the course of normal employee work activities of asphalt pavement milling at 11 different sites. Forty-two personal breathing zone air samples were collected over 21 days (sampling on an operator and ground worker each day). All samples were below 50 µg/m(3) for respirable crystalline silica, the National Institute for Occupational Safety and Health recommended exposure limit. The geometric mean personal breathing zone air sample was 6.2 µg/m(3) for the operator and 6.1 µg/m(3) for the ground worker for the Manufacturer A milling machine. The geometric mean personal breathing zone air sample was 4.2 µg/m(3) for the operator and 9.0 µg/m(3) for the ground worker for the Manufacturer B milling machine. In addition, upper 95% confidence limits for the mean exposure for each occupation were well below 50 µg/m(3) for both studies. The silica content in the bulk asphalt material being milled ranged from 7-23% silica for roads milled by Manufacturer A and from 5-12% silica for roads milled by Manufacturer B. The results indicate that engineering controls consisting of ventilation controls in combination with water-sprays are

  2. Eleven influential factors for quality of life in adults with epilepsy

    Institute of Scientific and Technical Information of China (English)

    Tongge Wang; Hao Wang; Jianhua Cheng

    2008-01-01

    BACKGROUND: Research focused on the quality of life of epileptic patients began only very recently in China; in particular, most research has focused on children, but less on epileptic adults.OBJECTIVE: To survey and analyze 11 influential factors for quality of life in adults with epilepsy by using quality of life epilepsy-31 scale.DESIGN: Cross-sectional study.SETTING: Department of Neurology, First Hospital Affiliated to Jinan University; Department of Neurology, First Affiliated Hospital of Wenzhou Medical College.PARTICIPANTS: A total of 107 adults with epilepsy for longer than one year were selected from Department of Neurology, First Hospital Affiliated to Jinan University between March 2004 and December 2006. The included patients met the Classification and Diagnostic Criteria of Epileptic Attack published by International Anti-Epilepsy League in 1981, and they provided informed consent. METHODS: General states, including course, attack frequency, marriage status, educational level, occupational types, economic status, attack types, drug types, and drug amount, were recorded. There were seven aspects in the Quality of Life Epilepsy-31 scale, including attack worry, life satisfaction, emotion, vigor/tiredness, drug influence, cognitive function, and social function. The scores positively correlated with the quality of life. Possible influential factors for quality of life were analyzed by one-way ANOVA and multivariate regression analysis.MAIN OUTCOME MEASURES: Course, attack frequency, marriage status, educational level, occupational types, economic status, attack types, drug types, drug amount, age, and sex.RESULTS: A total of 107 epileptic patients were included in the final analysis. Influential factors for quality of life in epileptic adults included attack frequency, educational level, economic status, attack types, drug amount, age, and course of disease (P < 0.05). Among them, attack frequency negatively correlated with attack worry, life

  3. Factors determining the outcome of management of patients with Burkitt's lymphoma at the University College Hospital Ibadan, Nigeria--an eleven year review.

    Science.gov (United States)

    Fasola, F A; Shokunbi, W A; Falade, A G

    2002-09-01

    In recent times, our experience in the chemotherapy of Burkitt's lymphoma patients in Ibadan, Nigeria has been that of poor outcome, hence this study was undertaken to determine the factors leading to the poor results of chemotherapy of Burkitt s lymphoma in Ibadan. A retrospective analysis of Burkitt s Lymphoma patients seen over eleven year period, between January 1987 to December 1997 at the Paediatrics and Haematology Departments of the University College Hospital, Ibadan was carried out. There were 67 patients, mean age 11+5 years (range 4 to 30 years), 42 males, 25 female giving M:F ratio of 1.7:1. Majority of the patients (76.2%) were stage D, only 4.5% were stages A and of the 67 patients, only 57 (83.6%) had chemotherapy, 40 of whom had COAP, 8 had COMP and 9 patients had either cyclophosphamide or cytosar as monotherapy. Only 22.8% of patients that received chemotherapy went into complete remission. In this study, we observed a declining overall complete remission rate of 22.8% (compared to 47% in 1979) in Burkitt s Lymphoma patients. The presence of large amount of fake drugs in the Nigerian market may imply that some of the cytotoxic drugs used in these patients could have been fake drugs. We suggest that the government should subsidize the therapy of these patients as well as eradicate the presence of fake drugs in the market, thereby increasing the chances of a cure.

  4. Nine-Elevenism

    Directory of Open Access Journals (Sweden)

    Juanjo Bermúdez de Castro

    2011-09-01

    Full Text Available The literary text is a time-and-place-bound verbal construction that is always in one way or another political. Because it is inevitably involved with one or more discourses or an ideology it cannot help being a vehicle for power. As a consequence, and just like any other text, literature does not simply reflect relations of power, but actively participates in the consolidation and/or construction of discourses and ideologies, just as functions as an instrument in the construction of identiti...

  5. Reading: Seven to Eleven.

    Science.gov (United States)

    Merritt, John E.

    This paper focuses on ways of improving reading by developing the intermediate skills and the higher order comprehension skills in reading. The paper consists of four sections: "Intermediate Skills and Context Cues" discusses the use of the cloze procedure for improving comprehension skills and for analyzing words in terms of class membership,…

  6. Study on Tautology in Eleven Ancient Medical Books%十一部古医籍重言之研究

    Institute of Scientific and Technical Information of China (English)

    崔锡章

    2001-01-01

    运用穷尽性研究方法,对《黄帝内经素问》等11部中医经典古籍中的重言现象进行分析.结果显示,重言用词具有重要的特点和作用,研究其释义和发展规律,对准确理解医理颇有意义.

  7. A Comparison Study of Eleven Static Heuristics for Mapping a Class of Independent Tasks onto Ileterogeneous Distributed Computing Systems

    OpenAIRE

    Braunt, Tracy D.; Siegel, Howard Jay; Beck, Noah; Boloni, Ladislau L.; Maheswarans, Muthucumaru; Reuthert, Albert I.; Robertson, James P.; Theys, Mitchell D.; Yao, Bin; Hensgeno, Debra; Freund, Richard F.

    2000-01-01

    ABSTRACT Il'lixed-machine heterogeneous computing (HC) environments utilize a distributed suite of different high-performance machines, interconnected with high-speed links to perform different computationally intensive applications that have diverse comput ational requirements. HC environments are well suited to meet thl: computational dell-tands of large, diverse groups of tasks. The problem of mapping (defined as matching and scheduling) these tasks onto the machines of a distributed HC en...

  8. CODEX-compliant eleven organophosphorus pesticides screening in multiple commodities using headspace-solid phase microextraction-gas chromatography-mass spectrometry.

    Science.gov (United States)

    Sang, Zi-Ye; Wang, Yu-Ting; Tsoi, Yeuk-Ki; Leung, Kelvin Sze-Yin

    2013-01-15

    A headspace-solid phase microextraction-gas chromatography-mass spectrometric (HS-SPME-GC-MS, hereafter abbreviated as "SPME") method was developed for dedicated organophosphorus (OP) pesticides assessment in multiple vegetable and fruit commodities. Specific extraction variables were optimised to achieve harmonised extraction performance of eleven OPs in a great span of seven characteristic commodities cataloged in Codex Alimentarius Commission. Comprehensive validation study confirmed analytical robustness of the SPME treatment in turnip, green cabbage, French beans, eggplant, apple, nectarine and grapes. Based on range-specific evaluation, extraction of individual OPs was characterised by sub-ppb level sensitivity and a wide 0.01-2.5 mg L(-1) dynamic range. Effective sample clean-up afforded precise quantification (0.5-10.9% R.S.D.) within a 70-120% recovery range at the MRL levels specified for individual commodities. Compared to conventional methods currently used, the SPME treatment developed here is quick, accurate, and relatively environmental friendly; it represents an attractive, practical way to deliver international standards in OP screening routines.

  9. The Scandinavian total ankle replacement: long-term, eleven to fifteen-year, survivorship analysis of the prosthesis in seventy-two consecutive patients.

    Science.gov (United States)

    Brunner, Samuel; Barg, Alexej; Knupp, Markus; Zwicky, Lukas; Kapron, Ashley L; Valderrabano, Victor; Hintermann, Beat

    2013-04-17

    The objective of this study was to determine the long-term survivorship and clinical and radiographic results of the Scandinavian Total Ankle Replacement (STAR). From February 1996 to March 2000, seventy-seven ankles in seventy-two patients (thirty-seven female and thirty-five male patients, with an average age of fifty-six years) underwent total ankle replacement using the STAR prosthesis with a single coating of hydroxyapatite. Two patients were lost to follow-up, and twelve patients with thirteen ankle replacements died. The average duration of follow-up for the patients without revision was 12.4 years (range, 10.8 to 14.9 years). Sixty-two of the seventy-seven ankles were available for final follow-up. Twenty-nine (38%) of the seventy-seven ankles had a revision of at least one of the metallic components. The probability of implant survival was 70.7% at ten years and 45.6% at fourteen years. The main reasons for revision were aseptic loosening, subsidence of the talar component, and progressive cyst formation. Polyethylene insert fractures were observed in eleven ankles. While the midterm to short-term results for patients managed with the STAR prosthesis have been encouraging at 3.7 years, the long-term survivorship of the same cohort was considerably inferior. The subjective and clinical results of the patients with retained prostheses are generally good and comparable with results reported in the current literature.

  10. Ionic liquid as a mobile phase additive in high-performance liquid chromatography for the simultaneous determination of eleven fluorescent whitening agents in paper materials.

    Science.gov (United States)

    Wang, Qing; Chen, Xianbo; Qiu, Bin; Zhou, Liang; Zhang, Hui; Xie, Juan; Luo, Yan; Wang, Bin

    2016-04-01

    In the present study, 11 4,4'-diaminostilbene-2,2'-disulfonic acid based fluorescent whitening agents with different numbers of sulfonic acid groups were separated by using an ionic liquid as a mobile phase additive in high-performance liquid chromatography with fluorescence detection. The effects of ionic liquid concentration, pH of mobile phase B, and composition of mobile phase A on the separation of fluorescent whitening agents were systematically investigated. The ionic liquid tetrabutylammonium tetrafluoroborate is superior to tetrabutylammomnium bromide for the separation of the fluorescent whitening agents. The optimal separation conditions were an ionic liquid concentration at 8 mM and the pH of mobile phase B at 8.5 with methanol as mobile phase A. The established method exhibited low limits of detection (0.04-0.07 ng/mL) and wide linearity ranges (0.30-20 ng/mL) with high linear correlation coefficients from 0.9994 to 0.9998. The optimized procedure was applied to analyze target analytes in paper samples with satisfactory results. Eleven target analytes were quantified, and the recoveries of spiked paper samples were in the range of 85-105% with the relative standard deviations from 2.1 to 5.1%. The obtained results indicated that the method was efficient for detection of 11 fluorescent whitening agents.

  11. Bamboo charcoal as a novel solid-phase microextraction coating material for enrichment and determination of eleven phthalate esters in environmental water samples.

    Science.gov (United States)

    Zhao, Ru-Song; Liu, Yan-Long; Zhou, Jia-Bin; Chen, Xiang-Feng; Wang, Xia

    2013-05-01

    This study demonstrates the potential of bamboo charcoal as a novel and inexpensive solid-phase microextraction (SPME) coating material for enrichment and determination of organic pollutants in water samples. Bamboo charcoal was prepared and used as a SPME coating material. Eleven phthalate esters (PAEs) were used as model analytes, and gas chromatography-mass spectrometry was used for separation and detection. Important extraction conditions (ionic strength, stirring rate, and extraction time) and desorption conditions (desorption temperature and time) were systematically investigated and optimized. Linearity of 0.1-100 μg L(-1) and correlation coefficients of 0.9992-0.9998 were obtained under optimum conditions. Inter-day and intra-day repeatability were 2.15-9.93 % and 1.89-9.85 %, respectively, and fiber-to-fiber reproducibility was 5.42-9.66 %. On the basis of a chromatographic signal-to-baseline noise ratio of three, the limits of detection reached 0.004-0.023 μg L(-1). Satisfactory results were achieved when the bamboo coating was used for determination of 11 PAEs in real water samples. The experimental results indicate that bamboo charcoal has significant potential as a SPME coating material for rapid enrichment and sensitive determination of organic pollutants in environmental samples.

  12. Age group athletes in inline skating: decrease in overall and increase in master athlete participation in the longest inline skating race in Europe – the Inline One-Eleven

    Directory of Open Access Journals (Sweden)

    Teutsch U

    2013-05-01

    Full Text Available Uwe Teutsch,1 Beat Knechtle,1,2 Christoph Alexander Rüst,1 Thomas Rosemann,1 Romuald Lepers31Institute of General Practice and Health Services Research, University of Zurich, Zurich, Switzerland; 2Gesundheitszentrum St Gallen, St Gallen, Switzerland; 3INSERM U1093, Faculty of Sport Sciences, University of Burgundy, Dijon, FranceBackground: Participation and performance trends in age group athletes have been investigated in endurance and ultraendurance races in swimming, cycling, running, and triathlon, but not in long-distance inline skating. The aim of this study was to investigate trends in participation, age, and performance in the longest inline race in Europe, the Inline One-Eleven over 111 km, held between 1998 and 2009.Methods: The total number, age distribution, age at the time of the competition, and race times of male and female finishers at the Inline One-Eleven were analyzed.Results: Overall participation increased until 2003 but decreased thereafter. During the 12-year period, the relative participation in skaters younger than 40 years old decreased while relative participation increased for skaters older than 40 years. The mean top ten skating time was 199 ± 9 minutes (range: 189–220 minutes for men and 234 ± 17 minutes (range: 211–271 minutes for women, respectively. The gender difference in performance remained stable at 17% ± 5% across years.Conclusion: To summarize, although the participation of master long-distance inline skaters increased, the overall participation decreased across years in the Inline One-Eleven. The race times of the best female and male skaters stabilized across years with a gender difference in performance of 17% ± 5%. Further studies should focus on the participation in the international World Inline Cup races.Keywords: endurance, men, women, gender

  13. The feature of papers and citation analysis of eleven journals in tropical medicine indexed by Science Citation Index Expanded.

    Science.gov (United States)

    Hua, Yang

    2005-11-01

    To determine the features of papers, authors, and citation of eleven journals in tropical medicine indexed by Science Citation Index Expanded, the database of the Institute for Scientific Information, we analyzed original articles, editorials, reviews, corrections, letters, biographies, and news published in these journals. The results show that these journals covered 107 countries or regions on six continents. The average number of reference was 23.05, with 87.89% of the references from periodicals. The Price Index was 31.43% and the self-citing rate was 7.02%. The references in the first 20 journals ranked by the amount of citation accounted for 36.71% of the total citations. Brazil, United States, India, and England are more advanced in tropical medicine research. The conclusion is that these journals covered most research done in these countries or regions. Most researches were done by cooperation of the researchers, but many of the publications used outdated articles and should include newer information.

  14. Analysis of self-fertilization and meiotic behavior of eleven Brazilian triticale cultivars at two sowing dates

    Directory of Open Access Journals (Sweden)

    Divanilde Guerra

    2011-01-01

    Full Text Available Eleven Brazilian hexaploid triticale cultivars (2n = 6x = 42, from three breeding programs, were evaluated for theirability of self-fertilization in 2006 and for meiotic behavior, meiotic index and pollen viability at two sowing dates in 2007. Highpotential of self-fertilization was observed, with values up to 89.52 %. Many irregularities were found in the meiotic analysis, suchas the presence of univalents, laggard chromosomes and micronuclei in tetrads, which compromised both meiotic behavior andmeiotic index. At the first sowing date, more suitable for normal plant development, overall mean values of 52.68 % for normal cellsand 64.95 % for meiotic index were observed. At the second sowing date, less appropriate for the crop, overall means of 52.23 %for normal cells and 58.24 % for meiotic index were obtained. Despite all the irregularities, considerable pollen viability wasobserved, reaching overall means of 92.08 % and 91.07 % for the first and second sowing dates, respectively.

  15. Prognostic performance of lymphocyte-to-monocyte ratio in diffuse large B-cell lymphoma: an updated meta-analysis of eleven reports

    Directory of Open Access Journals (Sweden)

    Sun HL

    2016-05-01

    Full Text Available Hui-Ling Sun,1,* Yu-Qin Pan,1,* Bang-Shun He,1 Zhen-Lin Nie,2 Kang Lin,1 Hong-Xin Peng,1,3 William C Cho,4 Shu-Kui Wang1 1Central Laboratory, 2Laboratory Medicine, Nanjing First Hospital, Nanjing Medical University, 3Medical College, Southeast University, Nanjing, 4Department of Clinical Oncology, Queen Elizabeth Hospital, Hong Kong, People’s Republic of China *These authors contributed equally to this work Purpose: The findings on the prognostic value of lymphocyte-to-monocyte ratio (LMR in diffuse large B-cell lymphoma (DLBCL are inconsistent. This meta-analysis was conducted to more precisely evaluate the prognostic significance of LMR in DLBCL. Methods: This analysis combined eleven studies with 4,578 patients aiming to assess the association of LMR with overall survival (OS and progression-free survival (PFS in DLBCL. Data from studies directly reporting a hazard ratio (HR with 95% corresponding confidence interval (CI in multivariate analysis were pooled to estimate the effect. Results: Our results suggested that patients with decreased LMR had shorter OS (HR =1.79, 95% CI =1.54–2.08, P<0.001 and PFS (HR =2.21, 95% CI =1.80–2.72, P<0.001 in DLBCL. Stratified analyses indicated that each confounder showed consistent prognostic value in DLBCL. There was no significant heterogeneity for PFS (PH=0.192 and OS (PH=0.212 among the enrolled studies. Conclusion: This meta-analysis indicated that decreased LMR might be a marker in the prediction of poor prognosis for patients with DLBCL. Keywords: diffuse large B-cell lymphoma, lymphocyte-to-monocyte ratio, meta-analysis, prognosis

  16. Condições de saúde e nível de atividade física em idosos participantes e não participantes de grupos de convivência de Florianópolis Health status and physical activity levels among the elderly who are participants and non-participants in social welfare groups in Florianópolis

    Directory of Open Access Journals (Sweden)

    Tânia Rosane Bertoldo Benedetti

    2012-08-01

    Full Text Available Objetivou-se verificar a associação entre condições de saúde e nível de atividade física em idosos participantes e não participantes de grupos de convivência de Florianópolis, Santa Catarina. A amostra foi constituída de 1.062 idosos (625 mulheres, com média de idade de 71,9 anos (±7,6. Foram analisadas as variáveis sociodemográficas (sexo, idade, escolaridade e estado civil, nível de atividade física (International Physical Activity Questionaire e saúde física (Questionário Brazil Older Aging Schedule. Os dados foram analisados por meio da estatística descritiva e teste Qui-quadrado. Os resultados demonstraram que 60,6% dos idosos foram classificados como ativos fisicamente. A presença de doenças foi relatada por 74% dos idosos, sendo que os participantes de grupos de convivência (GP apresentaram maior prevalência que o grupo não participante (GNP. Porém, mesmo com maior prevalência de doença, os idosos do GP apresentaram percepção positiva do estado de saúde. Para as mulheres, a participação em grupos de convivência associou-se positivamente com percepção do estado de saúde (p This study sought to verify the association between health status and physical activity levels among the elderly who are participants and non-participants in social welfare groups in Florianópolis in the State of Santa Catarina, Brazil. The sample included 1,062 elderly people (625 women, mean age 71.9 (±7.6. The variables analyzed were gender, age, schooling, marital status, physical activity levels (International Physical Activity Questionnaire and physical health status information (Brazil Elderly Schedule Questionnaire. Data were analyzed by Chi-square test. The results revealed that 60.6% were classified as physically active (total physical activity level and 74% of the elderly reported illness. Illness status was more prevalent among social welfare group participants than non-participants. However, a better positive

  17. Comparative evaluation of eleven commercial DNA extraction kits for real-time PCR detection of Bacillus anthracis spores in spiked dairy samples.

    Science.gov (United States)

    Mertens, Katja; Freund, Lisa; Schmoock, Gernot; Hänsel, Christoph; Melzer, Falk; Elschner, Mandy C

    2014-01-17

    Spores of Bacillus anthracis are highly resistant and can survive conditions used for food preservation. Sample size and complexity represent the major hurdles for pathogen detection in food-related settings. Eleven commercial DNA extraction kits were evaluated for detection of B. anthracis spores by quantitative real-time PCR (qPCR) in dairy products. DNA was extracted from serial dilutions of B. anthracis spores in milk powder, cream cheese, whole milk and buttermilk. Three kits (QIAamp DNA mini kit, Invisorb Food kit I and II) were determined to produce the lowest limit of detections (LODs) with equally good performance. These kits employed lysozyme and proteinase K treatments or proteinase K in combination with cethyltrimethylamonium bromide-mediated (CTAB) precipitation of cell debris for cell disruption and DNA release. The LODs for these three kits were determined as 10(2) spores/ml of distilled water, 10(3)s pores/20 mg of powdered milk and 10(4) spores/100 mg of cream cheese, respectively. Performance testing of the QIAamp DNA mini kit demonstrated a good reproducibility and appropriate detection limits from 10(3)/ml for butter milk, 10(4)/ml for whole milk and 10(4)/100 mg for low fat cream cheese. However, DNA extraction efficiency was strongly inhibited by cream cheese with higher fat contents with an increased LOD of 10(6)/100 mg spores. This study demonstrated that qPCR detection depends directly on the appropriate DNA extraction method for an individual food matrix and bacterial agent.

  18. Spondilodiscitis due to Mycobacterium tuberculosis in HIV and non-HIV-infected patients: Eleven years experience in a referent Hospital of infectious diseases in Argentina

    Directory of Open Access Journals (Sweden)

    Marcelo Corti

    2012-01-01

    Full Text Available Background: Tuberculosis (TB is an emerging health problem despite the advances in the methods of diagnosis and treatment. The resurgence of tuberculous spondilodiscitis (TBSD or Pott′s disease can be expected to be associated with a concomitant increase in the incidence of extra-pulmonary TB. Aim: To describe the clinical features, imaging findings, and laboratory diagnosis in a group of patients with TBSD. Materials and Methods: From January 1 st 2000 to December 31 st 2010, we retrospectively reviewed 22 cases of spinal TB. Only those with positive culture results and/or characteristic clinical and pathological findings were enrolled. Demographic data, comorbilities, clinical manifestations, time up to the definitive diagnosis, outcome and sequelae were considered. Results : During the study period, 22 patients were diagnosed with TBSD; 14 were men and 8 women with a median of age of 34 years at the time of diagnosis. The median duration of symptoms before the TBSD diagnosis was 120 days (range 30 to 360 days. At the time of diagnosis, fever and back pain were the most common clinical symptoms; 7 patients (32% had fever and 21 (95% had spinal pain; eleven patients (50% had constitutional symptoms; 6 (27% had respiratory symptoms and 3 (13.6% had neurological manifestations. Magnetic resonance imaging (MRI was performed in 9 (40% cases, computed tomography (CT in 7 patients (32%, and abdominal ultrasound in 6 cases (27%. The lumbar spine was the most commonly involved site (14 patients, 64%; thoracic spine was involved in 2 patients (9%; dorsolumbar spine was compromised in 4 cases (18%. Cervical spine was only involved in one patient (4.5% and the last patient (4.5% presents a global spinal involvement (cervical-thoracic and lumbar spine. Conclusion: Insidious clinical course and ambiguous manifestations of TBSD often delay the accuracy of diagnosis. Spinal TB should be included in the differential diagnosis of patients with prolonged back

  19. Genetic analysis of the response to eleven Colletotrichum lindemuthianum races in a RIL population of common bean (Phaseolus vulgaris L.).

    Science.gov (United States)

    Campa, Ana; Rodríguez-Suárez, Cristina; Giraldez, Ramón; Ferreira, Juan José

    2014-04-30

    Bean anthracnose is caused by the fungus Colletotrichum lindemuthianum (Sacc. & Magnus) Lams.- Scrib. Resistance to C. lindemuthianum in common bean (Phaseolus vulgaris L.) generally follows a qualitative mode of inheritance. The pathogen shows extensive pathogenic variation and up to 20 anthracnose resistance loci (named Co-), conferring resistance to specific races, have been described. Anthracnose resistance has generally been investigated by analyzing a limited number of isolates or races in segregating populations. In this work, we analyzed the response against eleven C. lindemuthianum races in a recombinant inbred line (RIL) common bean population derived from the cross Xana × Cornell 49242 in which a saturated linkage map was previously developed. A systematic genetic analysis was carried out to dissect the complex resistance segregations observed, which included contingency analyses, subpopulations and genetic mapping. Twenty two resistance genes were identified, some with a complementary mode of action. The Cornell 49242 genotype carries a complex cluster of resistance genes at the end of linkage group (LG) Pv11 corresponding to the previously described anthracnose resistance cluster Co-2. In this position, specific resistance genes to races 3, 6, 7, 19, 38, 39, 65, 357, 449 and 453 were identified, with one of them showing a complementary mode of action. In addition, Cornell 49242 had an independent gene on LG Pv09 showing a complementary mode of action for resistance to race 453. Resistance genes in genotype Xana were located on three regions involving LGs Pv01, Pv02 and Pv04. All resistance genes identified in Xana showed a complementary mode of action, except for two controlling resistance to races 65 and 73 located on LG Pv01, in the position of the previously described anthracnose resistance cluster Co-1. Results shown herein reveal a complex and specific interaction between bean and fungus genotypes leading to anthracnose resistance. Organization

  20. Representativeness in population-based studies

    DEFF Research Database (Denmark)

    Drivsholm, Thomas Bo; Eplov, Lene Falgaard; Davidsen, Michael;

    2006-01-01

    Decreasing rates of participation in population-based studies increasingly challenge the interpretation of study results, in both analytic and descriptive epidemiology. Consequently, estimates of possible differences between participants and non-participants are increasingly important for the int...

  1. Prevalência do exame preventivo de câncer do colo do útero em Rio Branco, Acre, Brasil, e fatores associados à não-realização do exame Prevalence of uterine cervical cancer testing in Rio Branco, Acre State, Brazil, and factors associated with non-participation in screening

    Directory of Open Access Journals (Sweden)

    Maria Fernanda de Sousa Oliveira Borges

    2012-06-01

    Full Text Available O objetivo do estudo foi determinar a prevalência autorreferida do exame preventivo de câncer do colo uterino em Rio Branco, Acre, Brasil, e avaliar fatores associados com a não realização do exame. Trata-se de estudo transversal de base populacional, composto por 772 mulheres de 18 a 69 anos residentes em Rio Branco, no período 2007 a 2008. Os dados foram analisados no programa Stata 10.0 e estimadas razões de prevalências a partir da regressão multivariada de Poisson. O percentual de mulheres na população alvo que relatou pelo menos um exame nos últimos três anos foi de 85,3%, com acentuada utilização do Sistema Único de Saúde (72,8%. Foram encontradas razões de prevalência estatisticamente significativas quanto à ausência do exame em mulheres de 18 a 24 anos, de 60 a 69 anos, solteiras, com menor renda e baixa escolaridade. As magnitudes encontradas nas razões de prevalência foram consistentes com achados de outros estudos, apontando maior necessidade de intervenção no grupo de mulheres mais vulneráveis à incidência e mortalidade por câncer do colo do útero.The objective of the study was to determine the self-reported prevalence of uterine cervical cancer testing in Rio Branco, Acre State, Brazil, and to analyze factors associated with non-participation in screening. A population-based cross-sectional study with a sample of 772 women 18 to 69 years of age and living in Rio Branco was conducted in 2007 and 2008. Data were analyzed with Stata 10.0, and prevalence rates were estimated with Poisson multivariate regression (95%CI. 85.3% of women reported at least one cervical cancer screening test in the previous three years. The majority of women (72.8% were screened in the Brazilian Unified National Health System. After adjusting for selected variables, statistically significant prevalence rates for absence of screening were found in women 18-24 and 60-69 years of age, single, and with low income and low schooling

  2. Participación y no participación en educación de personas adultas en España. Un enfoque comunicativo y crítico en investigación Participation and non-participation in adult education in Spain. A communicative and critical approach

    Directory of Open Access Journals (Sweden)

    1998-08-01

    Full Text Available A atual sociedade de informação vem produzindo um incremento das necessidades e demandas por formação. Na maioria dos casos, a oferta existente favorece as pessoas com maiores níveis de escolarização, excluindo os setores sociais com menores níveis de instrução escolar. Caso se baseasse em métodos estritamente quantitativos, a pesquisa sobre participação e não participação de pessoas adultas em cursos de formação poderia legitimar políticas culturais seletivas e contribuir para tal exclusão. A combinação de metodologias quantitativas e qualitativas permite caracterizar a relevância social do objeto de estudo e, simultaneamente, captar as reflexões, as motivações e as interpretações dos próprios atores, sejam eles participantes ou não participantes. Este estudo apresenta uma descrição da realidade na Catalunha e tem por objetivo proporcionar pautas para uma transformação que favoreça a participação de todos os grupos sociais.In the current information society there was a strong increase of the needs and training demands. The offer favours, in most cases, the persons with higher studies level and excludes social sectors with low levels of schooling. The research on participation and non participation would contribute to this exclusion and to legitimate cultural policies if its analysis were based exclusively in quantitative studies. The combination of quantitative and qualitative methodologies allows us to, besides characterising the social importance of the object of study, obtain reflection, motivations and interpretations from the actors. This research presents a description of the reality and his end is to provide standards for a transformation that favours the participation of all the social groups

  3. Cinco pacientes, once colgajos libres: resultados a largo plazo Five patients, eleven free flaps: long-term results

    Directory of Open Access Journals (Sweden)

    C. Olvera Caballero

    2006-09-01

    Full Text Available Los colgajos libres resuelven problemas complejos. En situaciones en donde existe gran pérdida de tejidos u otros métodos reconstructivos han fracasado se puede lograr restablecer la forma y la función utilizándolos. En este trabajo se presentan cinco pacientes en los que se usaron once colgajos libres (2 por paciente en cuatro casos, tres en otro y sus resultados a largo plazo con un mínimo de seguimiento de 7 años y un máximo de 17 años. Las indicaciones para utilizar más de un colgajo libre en un paciente son: reponer un primer colgajo perdido, por complejidad del problema, por experiencia del cirujano o por deseo expreso del paciente para una reconstrucción similar. En nuestra serie, la complejidad del problema fue la principal indicación de usar este método doble y triple. Cuatro pacientes recibieron los colgajos en los miembros inferiores y uno en la cara. Las etiologías encontradas fueron: secuelas de quemaduras en dos casos, secuelas posttraumáticas en otros dos y secuelas postquirúrgicas y de mielomeningocele en uno. Se utilizaron cuatro colgajos de dorsal ancho, cinco escapulares, uno de peroné y uno de gracilis. El seguimiento a largo plazo nos permite mostrar la gran adaptabilidad de los colgajos libres, su resistencia y su valor como procedimiento reconstructivo de primera opciónFree flaps are useful to solve complex problems. Whenever there is an extensive loss of tissues or when other reconstructive methods have failed, they may provide the means to restore shape and function. This paper deals with five patients in whom eleven free flaps were used (two in four patients and three in one more case to solve complex problems. Furthermore, long-term results are reported, with follow-up ranging from 7 to 17 years Indications to use more than one free flap in a patient are: replacing a first flap that was lost, a highly complex problem, the surgeon’s expertise, or when the patient wish for a similar reconstruction. In

  4. Polyhedral metallaheteroborane chemistry. Synthesis, spectroscopy, structure and dynamics of eleven-vertex {RhNB(9)} and {PtCB(9)} metallaheteroboranes.

    Science.gov (United States)

    Macías, Ramón; Bould, Jonathan; Holub, Josef; Kennedy, John D; Stíbr, Bohumil; Thornton-Pett, Mark

    2007-07-21

    Reaction between [RhCl(PPh(3))(3)] and the [nido-6-NB(9)H(11)](-) anion in CH(2)Cl(2) yields orange eleven-vertex [8,8-(PPh(3))(2)-nido-8,7-RhNB(9)H(11)]. Reaction of the [nido-6-CB(9)H(12)](-) anion with [cis-PtCl(2)(PMe(2)Ph)(2)] in methanol affords yellow eleven-vertex [9-(OMe)-8,8-(PMe(2)Ph)(2)-nido-8,7-PtCB(9)H(10)], which is also formed from the reaction of MeOH with [8,8-(PPh(3))(2)-nido-8,7-PtCB(9)H(10)]. Both compounds have been characterised by single-crystal X-ray diffraction analysis and examined by NMR spectroscopy and have structures based on eleven-vertex nido-type geometries, with the metal centre and the heteroatoms in the adjacent (8)- and (7)-positions on the pentagonal open face. The metal-to-heteroborane bonding sphere of is fluxional, with a DeltaG(double dagger) value of 48.4 kJ mol(-1). DFT calculations on the model compounds [8,8-(PH(3))(2)-nido-8,7-RhNB(9)H(11)] and [8,8-(PH(3))(2)-nido-8,7-RhSB(9)H(10)] have been carried out to define the fluxional process and the intermediates involved.

  5. Sr fluxes and isotopic compositions of the eleven rivers originating from the Qinghai-Tibet Plateau and their contributions to 87Sr/86Sr evolution of seawater

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    To evaluate influence of chemical weathering of the Qinghai-Tibet Plateau (QTP) on seawater 87Sr/86Sr variation, river water and sediment samples were collected, and their Sr concentrations and isotopic compositions analyzed, from the seven large rivers that originated from the QTP. By combining these with the data of the Ganges, Brahmaputra, Indus and Irrawaddy originated in the southern QTP, the total Sr flux of the eleven rivers reaches 3.47×109 mol·a-1, which accounts for 10.2% of the total Sr flux transported by the global rivers. The weighted mean 87Sr/86Sr is 0.71694, higher than the average value of the global rivers. The 87Srex (87Sr flux in excess of the seawater 87Sr/86Sr ratio) of the Chinese seven rivers is 1.55×106 mol·a-1, only accounting for about 6% of the value of the eleven rivers originated from QTP, and the Ganges-Brahmaputra system accounts for 86%. We assume that the QTP rivers have no strontium contributions to the oceans before ~40 Ma and the Sr fluxes of the global rivers, except the QTP eleven rivers, are constant, then a maximum linear increase in Sr fluxes of the QTP rivers from zero to the modern value in response to tectonic uplift can explain ~69% increase of seawater 87Sr/86Sr over the past ~40 Ma and the remainder of 31% is perhaps provided from other factors.

  6. Buccal mucosal graft urethroplasty for proximal bulbar urethral stricture: A revisit of the surgical technique and analysis of eleven consecutive cases

    Directory of Open Access Journals (Sweden)

    Irekpita Eshiobo

    2016-01-01

    Full Text Available Background: Urethral stricture disease is prevalent, and many surgical techniques have been developed to treat it. Currently, urethroplasty for bulbar strictures implies ventral or dorsal stricturotomy and a buccal mucosa graft (BMG patch. Objective: To describe the surgical approach of the ventral patch BMG urethroplasty for proximal bulbar urethral stricture and to analyze 11 consecutive cases for whom the technique was used. Patients and Methods: The diagnosis of urethral stricture was confirmed with a combined retrograde urethrography and micturating cystourethrography. A single team exposed the urethra, harvested, and planted the BMG in the lithotomy position under general anesthesia. The oral preoperative preparation was done with oraldene (hexetidine mouth wash three times daily beginning from the 2nd preoperative day. The buccal mucosa was harvested from the left inner cheek in all the patients. The donor site was left unclosed but packed with wet gauze. Data related to age, preoperative adverse conditions, stricture length, urine culture result, perineal/oral wound complications, postoperative residual urine volume, and duration of hospital stay were recorded. Results: Eleven patients with proximal bulbar urethral stricture had BMG urethroplasty from August 2013 to October 2015. Stricture length ranged from 2 to 5 cm. In six (54% of the men, the stricture resulted from urethritis thereby constituting the most common etiology of urethral stricture in this study. The preoperative adverse conditions were age above 70 in three, diabetes mellitus in two, severe dental caries in one, and recurrent stricture in two. All of them were able to resume reasonable oral intake 72 h postoperatively. One (9.2% had perineal wound infection, while two (18.2% still had mild pain at donor site 4 weeks postoperatively. Ten (90.9% of the 11 patients had <30 ml residual urine volume at 2 months of follow-up. Conclusion: Urethritis is still a common cause of

  7. MiR-520b suppresses proliferation of hepatoma cells through targeting ten-eleven translocation 1 (TET1) mRNA

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Weiying; Lu, Zhanping; Gao, Yuen [State Key Laboratory of Medicinal Chemical Biology, Department of Cancer Research, College of Life Sciences, Nankai University, Tianjin (China); Ye, Lihong [State Key Laboratory of Medicinal Chemical Biology, Department of Biochemistry, College of Life Sciences, Nankai University, Tianjin (China); Song, Tianqiang, E-mail: tjchi@hotmai.com [Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin (China); Zhang, Xiaodong, E-mail: zhangxd@nankai.edu.cn [State Key Laboratory of Medicinal Chemical Biology, Department of Cancer Research, College of Life Sciences, Nankai University, Tianjin (China)

    2015-05-08

    Accumulating evidence indicates that microRNAs are able to act as oncogenes or tumor suppressor genes in human cancer. We previously reported that miR-520b was down-regulated in hepatocellular carcinoma (HCC) and its deregulation was involved in hepatocarcinogenesis. In the present study, we report that miR-520b suppresses cell proliferation in HCC through targeting the ten-eleven translocation 1 (TET1) mRNA. Notably, we identified that miR-520b was able to target 3′-untranslated region (3′UTR) of TET1 mRNA by luciferase reporter gene assays. Then, we revealed that miR-520b was able to reduce the expression of TET1 at the levels of mRNA and protein using reverse transcription-polymerase chain reaction and Western blotting analysis. In terms of function, 5-ethynyl-2-deoxyuridine (EdU) incorporation and colony formation assays demonstrated that the forced miR-520b expression remarkably inhibited proliferation of hepatoma cells, but TET1 overexpression could rescue the inhibition of cell proliferation mediated by miR-520b. Furthermore, anti-miR-520b enhanced proliferation of hepatoma cells, whereas silencing of TET1 abolished anti-miR-520b-induced acceleration of cell proliferation. Then, we validated that the expression levels of miR-520b were negatively related to those of TET1 mRNA in clinical HCC tissues. Thus, we conclude that miR-520b depresses proliferation of liver cancer cells through targeting 3′UTR of TET1 mRNA. Our finding provides new insights into the mechanism of hepatocarcinogenesis. - Highlights: • TET1 is a novel target gene of miR-520b. • TET1 is upregulated in clinical HCC tissues. • MiR-520b is negatively correlated with TET1 in clinical HCC tissues. • MiR-520b depresses the proliferation of HCC cells through targeting TET1 mRNA.

  8. Eleven-dimensional gauge theory for the M-algebra as an Abelian semigroup expansion of osp (32 vertical stroke 1)

    Energy Technology Data Exchange (ETDEWEB)

    Izaurieta, F.; Rodriguez, E. [Universidad Catolica de la Santisima Concepcion, Departamento de Matematicas y Fisica Aplicadas, Concepcion (Chile); Universidad de Concepcion, Departamento de Fisica, Concepcion (Chile); Salgado, P. [Universidad de Concepcion, Departamento de Fisica, Concepcion (Chile)

    2008-04-15

    A new Lagrangian realizing the symmetry of the M-algebra in eleven-dimensional space-time is presented. By means of the novel technique of Abelian semigroup expansion, a link between the M-algebra and the orthosymplectic algebra osp(32 vertical stroke 1) is established, and an M-algebra-invariant symmetric tensor of rank six is computed. This symmetric invariant tensor is a key ingredient in the construction of the new Lagrangian. The gauge-invariant Lagrangian is displayed in an explicitly Lorentz-invariant way by means of a subspace separation method based on the extended Cartan homotopy formula. (orig.)

  9. Identification and Characterization of Eleven Novel Human Gamma-Papillomavirus Isolates from Healthy Skin, Found at Low Frequency in a Normal Population

    OpenAIRE

    Li, Jingjing; Pan, Yaqi; Deng, QiuJu; Cai, Hong; Ke, Yang

    2013-01-01

    Eleven novel human papillomavirus (HPV) types were isolated and characterized from healthy individuals in China. HPV163 belongs to the γ-1 species, HPV 164 and HPV 168 fit in the γ-8 species, HPV 165 and KC5 belongs to the γ-12 species, HPV 168 is closely allied with the γ-4 species, HPV 169 is closely related to the γ-11 species, and HPV 170 is related to the γ-12 species. In addition, HPV 161, HPV 162, and HPV 166 may form a new HPV species of the γ-PV genus. The prevalence of these HPV typ...

  10. IDENTIFYING ELEVEN FACTORS OF SERVICE MARKETING MIX (4PS) EFFECTIVE ON TENDENCY OF PATIENTS TOWARD PRIVATE HOSPITAL

    OpenAIRE

    Hosseini, Seyed Mojtaba; Etesaminia, Samira; Jafari, Mehrnoosh

    2016-01-01

    Introduction: One of the important factors of correct management is to identify the reasons for patient tendency toward private hospitals. This study measures these factors based on service marketing mixes. Patients and methods: This study used a cross sectional descriptive methodology. The study was conducted during 6 months in 2015. The studied population included patients of private hospitals in Tehran. Random sampling was used (n = 200). Data was collected by an author-made questionnaire ...

  11. Parcels and Land Ownership, Separate county layers for an eleven county region. Each layer uses a common field structure. The same information is not available for all counties., Published in 2007, NC Dept of Commerce - DCA.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Parcels and Land Ownership dataset, was produced all or in part from Other information as of 2007. It is described as 'Separate county layers for an eleven...

  12. IDENTIFYING ELEVEN FACTORS OF SERVICE MARKETING MIX (4PS) EFFECTIVE ON TENDENCY OF PATIENTS TOWARD PRIVATE HOSPITAL.

    Science.gov (United States)

    Hosseini, Seyed Mojtaba; Etesaminia, Samira; Jafari, Mehrnoosh

    2016-10-01

    One of the important factors of correct management is to identify the reasons for patient tendency toward private hospitals. This study measures these factors based on service marketing mixes. This study used a cross sectional descriptive methodology. The study was conducted during 6 months in 2015. The studied population included patients of private hospitals in Tehran. Random sampling was used (n = 200). Data was collected by an author-made questionnaire for service marketing factors. Reliability and validity of the questionnaire were confirmed. Data analysis was done using factor analysis test in SPSS 20. The results showed that constant attendance of physicians and nurses has the highest effect (0.707%) on patient tendency toward private hospitals.

  13. IDENTIFYING ELEVEN FACTORS OF SERVICE MARKETING MIX (4PS) EFFECTIVE ON TENDENCY OF PATIENTS TOWARD PRIVATE HOSPITAL

    Science.gov (United States)

    Hosseini, Seyed Mojtaba; Etesaminia, Samira; Jafari, Mehrnoosh

    2016-01-01

    Introduction: One of the important factors of correct management is to identify the reasons for patient tendency toward private hospitals. This study measures these factors based on service marketing mixes. Patients and methods: This study used a cross sectional descriptive methodology. The study was conducted during 6 months in 2015. The studied population included patients of private hospitals in Tehran. Random sampling was used (n = 200). Data was collected by an author-made questionnaire for service marketing factors. Reliability and validity of the questionnaire were confirmed. Data analysis was done using factor analysis test in SPSS 20. Results: The results showed that constant attendance of physicians and nurses has the highest effect (0.707%) on patient tendency toward private hospitals. PMID:27999486

  14. Management of fourth degree obstetric perineal tear without colostomy using non - stimulated gracilis - our experience over eleven years

    OpenAIRE

    Jiten Kulkarni; Patil, Anuradha J.; Bhaskar Musande; Abhishek B Bhamare

    2016-01-01

    Background: Although gracilis muscle transposition for faecal incontinence has been well-described method, its literature for use in obstetric perineal tear without colostomy is sparse. In this study, we have tried to analyse its use in fourth-degree obstetric perineal tears. Patients and Methods: A total of 30 patients with recto-vaginal fistula with faecal incontinence secondary to obstetric perineal tear were retrospectively studied between February 2003 and May 2014. The recto-vaginal fis...

  15. Organic acids, sugars, vitamin C content and some pomological characteristics of eleven hawthorn species (Crataegus spp.) from Turkey.

    Science.gov (United States)

    Gundogdu, Muttalip; Ozrenk, Koray; Ercisli, Sezai; Kan, Tuncay; Kodad, Ossama; Hegedus, Attila

    2014-05-30

    The Hawthorn (Crateagus sp.) mostly occurs around the temperate region of the world with a high number of species, producing a fruit with numerous beneficial effects for human health. The aim of the study was to determine organic acid and sugar contents in the fruit of a number of hawthorn species grown in Erzincan province of Turkey. Citric acid was the predominant organic acid in all hawthorn species and C. pseudoheterophylla had the highest citric acid content (23.688 g/100 g). There were not statistically significant differences among hawthorn species (except C. atrosanguinea Pojark) in terms of fumaric acid content. C.pontica C.Koch had a higher content of vitamin C (9.418 mg/100 g) compared to other species. Fructose was the predominant sugar component in all species and C. monogyna subsp. monogyna Joiq had the highest fructose content (18.378 g/100 g). The high fruit quality of the studied species indicates the importance of this fruit in human nutrition as a natural source. The study revealed that there were differences in terms of fruit characteristics among hawthorn species and thus better quality hawthorn genotypes can be selected within the species. Hence, this study is considered to be a valuable reference for forthcoming studies. The high fruit quality of the studied species indicates the importance of this fruit in human nutrition as a natural source.

  16. Electronic health record usability: analysis of the user-centered design processes of eleven electronic health record vendors.

    Science.gov (United States)

    Ratwani, Raj M; Fairbanks, Rollin J; Hettinger, A Zachary; Benda, Natalie C

    2015-11-01

    The usability of electronic health records (EHRs) continues to be a point of dissatisfaction for providers, despite certification requirements from the Office of the National Coordinator that require EHR vendors to employ a user-centered design (UCD) process. To better understand factors that contribute to poor usability, a research team visited 11 different EHR vendors in order to analyze their UCD processes and discover the specific challenges that vendors faced as they sought to integrate UCD with their EHR development. Our analysis demonstrates a diverse range of vendors' UCD practices that fall into 3 categories: well-developed UCD, basic UCD, and misconceptions of UCD. Specific challenges to practicing UCD include conducting contextually rich studies of clinical workflow, recruiting participants for usability studies, and having support from leadership within the vendor organization. The results of the study provide novel insights for how to improve usability practices of EHR vendors.

  17. Eleven years' effect of conservation practices for temperate sandy loams: I. Soil physical properties and topsoil carbon content

    DEFF Research Database (Denmark)

    Abdollahi, Lotfallah; Getahun, Gizachew Tarekegn; Munkholm, Lars Juhl

    2017-01-01

    experiments were conducted in 11- to 12-yr-old experiments on two Danish sandy loams at Foulum and Flakkebjerg. Three crop rotations/residue management treatments were compared and tillage was included as a splitplot factor. The tillage systems were moldboard plowing to a depth of 20 cm (MP), direct drilling...... their important role in soil structure formation and stabilization. Our study showed benefits of combining key CA elements, although longer-term studies are most likely needed to reveal the full potential....

  18. Patterns of non-participation in breast cancer screening

    DEFF Research Database (Denmark)

    Jensen, Line Flytkjær

    2015-01-01

    Screening for brystkræft blev introduceret i Region Midtjylland i 2008-2009 for kvinder i alderen 50-69 år for at øge overlevelsen ved at fange sygdommen tidligt. En høj deltagelse i screeningen er afgørende, hvis dødeligheden for brystkræft fremover skal reduceres. I første screeningsrunde delto...

  19. Psychiatric morbidity and non-participation in breast cancer screening

    DEFF Research Database (Denmark)

    Jensen, Line Flytkjær; Pedersen, Anette Fischer; Bech, Bodil Hammer

    2015-01-01

    Dette registerstudie undersøger sammenhængen mellem psykiatrisk morbiditet og ikke-deltagelse i brystkræftscreening. Kvinder med en indikation på psykisk morbiditet havde en 21 % øget sandsynlighed for ikke-deltagelse sammenliget med kvinder uden indikation på psykiatrisk morbiditet (95 % CI: 18-...

  20. Patterns of non-participation in breast cancer screening

    DEFF Research Database (Denmark)

    Jensen, Line Flytkjær

    2015-01-01

    Screening for brystkræft blev introduceret i Region Midtjylland i 2008-2009 for kvinder i alderen 50-69 år for at øge overlevelsen ved at fange sygdommen tidligt. En høj deltagelse i screeningen er afgørende, hvis dødeligheden for brystkræft fremover skal reduceres. I første screeningsrunde deltog...... screeningsenheden har af betydning. Resultaterne viser, at de kvinder, der ikke kom til screening, hyppigst var at finde blandt kvinder med lav social position, kvinder med flere kroniske sygdomme og kvinder med bopæl langt væk fra screeningsenheden. Resultaterne viser dog også, at kvinder med høj uddannelse deltog...... drage fordel af ekstra støtte eller særlige interventioner, når de skal beslutte, om de vil deltage i screening. Derfor bør fremtidige tiltag, som har til formål at øge deltagelsen, tage højde for individuelle, sociale og organisatoriske barrierer....

  1. Non-Participation in Guidance: An Opportunity for Development?

    Science.gov (United States)

    Thomsen, Rie

    2014-01-01

    This article discusses how new opportunities for guidance can emerge from an analysis of the interplay between the participation (or lack of participation) of the individuals in career guidance, and the career guidance practitioner's response. The article suggests critical psychology as a framework for career guidance research and presents…

  2. Eleven-month-old infants infer differences in the hardness of object surfaces from observation of penetration events.

    Directory of Open Access Journals (Sweden)

    Tomoko eImura

    2015-08-01

    Full Text Available Previous studies have shown different developmental trajectories for object recognition of solid and non-solid objects. However, there is no evidence as to whether infants have expectations regarding certain attributes of objects, such as surface hardness, in the absence of tactile information. In the present study, we examined infants’ perception of the hardness of object surfaces from visually presented penetration events using the familiarization–novelty preference procedure. Experiment 1 showed that by 11 months old infants distinguished a relatively soft surface from a crusty surface based on changes in the velocity of a moving object as the moving object penetrated the surface of the target object. Experiment 2 ruled out the possibility that infants were merely sensitive to differences in the velocity changes in the stimuli.

  3. Eleven-year response of foliar chemistry to chronic nitrogen and sulfur additions at the Bear Brook watershed in Maine

    Energy Technology Data Exchange (ETDEWEB)

    Elvir, J.A. [National School of Forest Science, Comayagua (Honduras); Rustad, L. [United States Dept. of Agriculture, Durham, NH (United States). Forest Service Northeastern Research Station; Wiersma, G.B.; White, A.S. [Maine Univ., Orono, ME (United States). Dept. of Forest Ecosystem Science; Fernandez, I. [Maine Univ., Orono, ME (United States). Dept. of Plant, Soil and Environmental Studies; White, G.J. [Idaho National Engineering and Environmental Laboratory, Idaho Falls, ID (United States)

    2005-06-01

    Foliar nutrient imbalances have been noted in trees growing in controlled nitrogen-fertilization experiments over areas of different nitrogen deposition rates and along N deposition gradients. Long-term foliar nutrient concentration data is not generally available because of a lack of long-term nitrogen studies and systematic measurements. This study at the Bear Brook Watershed in Maine (BBWM) focused on temporal changes in the foliar nutrient concentrations in sugar maple, American beech, and red spruce. The foliar chemistry was studied from 1993 to 2003 at the paired-watershed forest ecosystem of the BBWM study in which 1 watershed was treated bimonthly since 1989 with ammonium sulfate at a rate of about 25 kg of nitrogen per hectare per year. Foliar nitrogen concentrations were higher in all tree species within the treated watershed compared with trees within the reference watershed. Calcium and magnesium concentrations in the foliage were found to be lower in the American beech and red spruce within the treated watershed. Potassium concentrations did not vary between the 2 watersheds and the differences in phosphorous and manganese concentrations were inconsistent from one year to another. The differences in nitrogen concentrations in the foliage of sugar maple declined over time between the 2 watersheds. Differences in foliar calcium and magnesium concentrations between the treated and reference watersheds increased over time for American beech and red spruce, mostly due to the steady decline in concentrations of these nutrients in trees within the treated watershed. There was no noted temporal trend in sugar maple foliar calcium and magnesium concentrations between the watersheds. It was concluded that the watersheds of the BBWM may be in the later stages of nitrogen saturation, where the supply of nitrogen exceeds the nitrogen demand of plants and microorganisms in the ecosystem. 48 refs., 2 tabs., 6 figs.

  4. Management of fourth degree obstetric perineal tear without colostomy using non - stimulated gracilis - our experience over eleven years

    Directory of Open Access Journals (Sweden)

    Jiten Kulkarni

    2016-01-01

    Full Text Available Background: Although gracilis muscle transposition for faecal incontinence has been well-described method, its literature for use in obstetric perineal tear without colostomy is sparse. In this study, we have tried to analyse its use in fourth-degree obstetric perineal tears. Patients and Methods: A total of 30 patients with recto-vaginal fistula with faecal incontinence secondary to obstetric perineal tear were retrospectively studied between February 2003 and May 2014. The recto-vaginal fistula was explored, dissected and identification of sphincters was done using muscle stimulator. Fistula closure was done followed by sphincter repair, vaginal tightening procedure and single gracilis transposition. None of the patients had covering colostomy. Faecal incontinence was assessed pre- and post-operatively by digital rectal examination (single examiner, Park's score and Corman's score in all cases and using barium hold and transperineal ultrasonography, manometric studies in a few cases. The outcome was measured at an average follow-up of 8.8 months (7–24 months. Results: As per Park's score 26 patients had Grade I continence, two had Grade II and two patients had Grade III continence. Corman's score improved from fair to excellent in 26 patients. The patients in whom manometry was performed showed a remarkable rise in both resting and squeeze pressures. Two patients developed post-operative infections in upper 1/3 thigh incision site and three patients at gluteal region scar site. Conclusion: Satisfactory continence following gracilis muscle could be achieved.

  5. The spatial-temporal clustering of Plasmodium falciparum infection over eleven years in Gezira State, The Sudan

    Directory of Open Access Journals (Sweden)

    Snow Robert W

    2010-06-01

    Full Text Available Abstract Background Malaria infection and disease exhibit microgeographic heterogeneity which if predictable could have implications for designing small-area intervention. Here, the space-time clustering of Plasmodium falciparum infections using data from repeat cross-sectional surveys in Gezira State, a low transmission area in northern Sudan, is investigated. Methods Data from cross-sectional surveys undertaken in January each year from 1999-2009 in 88 villages in the Gezira state were assembled. During each survey, about a 100 children between the ages two to ten years were sampled to examine the presence of P. falciparum parasites. In 2009, all the villages were mapped using global positioning systems. Cluster level data were analysed for spatial-only and space-time clustering using the Bernoulli model and the significance of clusters were tested using the Kulldorff scan statistic. Results Over the study period, 96,022 malaria slide examinations were undertaken and the P. falciparum prevalence was 8.6% in 1999 and by 2009 this had reduced to 1.6%. The cluster analysis showed the presence of one significant spatial-only cluster in each survey year and one significant space-time cluster over the whole study period. The primary spatial-only clusters in 10/11 years were either contained within or overlapped with the primary space-time cluster. Conclusion The results of the study confirm the generally low malaria transmission in the state of Gezira and the presence of spatial and space-time clusters concentrated around a specific area in the south of the state. Improved surveillance data that allows for the analysis of seasonality, age and other risk factors need to be collected to design effective small area interventions as Gezira state targets malaria elimination.

  6. A mega-ethnography of eleven qualitative evidence syntheses exploring the experience of living with chronic non-malignant pain.

    Science.gov (United States)

    Toye, Fran; Seers, Kate; Hannink, Erin; Barker, Karen

    2017-08-01

    Each year over five million people develop chronic non-malignant pain and can experience healthcare as an adversarial struggle. The aims of this study were: (1) to bring together qualitative evidence syntheses that explore patients' experience of living with chronic non-malignant pain and develop conceptual understanding of what it is like to live with chronic non-malignant pain for improved healthcare; (2) to undertake the first mega-ethnography of qualitative evidence syntheses using the methods of meta-ethnography. We used the seven stages of meta-ethnography refined for large studies. The innovation of mega-ethnography is to use conceptual findings from qualitative evidence syntheses as primary data. We searched 7 bibliographic databases from inception until February 2016 to identify qualitative evidence syntheses that explored patients' experience of living with chronic non-malignant pain. We identified 82 potential studies from 556 titles, screened 34 full text articles and included 11 qualitative evidence syntheses synthesising a total of 187 qualitative studies reporting more than 5000 international participants living with chronic pain. We abstracted concepts into 7 conceptual categories: (1) my life is impoverished and confined; (2) struggling against my body to be me; (3) the quest for the diagnostic 'holy grail'; (4) lost personal credibility; (5) trying to keep up appearances; (6) need to be treated with dignity; and (7) deciding to end the quest for the grail is not easy. Each conceptual category was supported by at least 7 of the 11 qualitative evidence syntheses. This is the first mega-ethnography, or synthesis of qualitative evidence syntheses using the methods of meta-ethnography. Findings help us to understand that the decision to end the quest for a diagnosis can leave patients feeling vulnerable and this may contribute to the adversarial nature of the clinical encounter. This knowledge demonstrates that treating a patient with a sense that they

  7. Optimal installation locations for automated external defibrillators in Taipei 7-Eleven stores: using GIS and a genetic algorithm with a new stirring operator.

    Science.gov (United States)

    Huang, Chung-Yuan; Wen, Tzai-Hung

    2014-01-01

    Immediate treatment with an automated external defibrillator (AED) increases out-of-hospital cardiac arrest (OHCA) patient survival potential. While considerable attention has been given to determining optimal public AED locations, spatial and temporal factors such as time of day and distance from emergency medical services (EMSs) are understudied. Here we describe a geocomputational genetic algorithm with a new stirring operator (GANSO) that considers spatial and temporal cardiac arrest occurrence factors when assessing the feasibility of using Taipei 7-Eleven stores as installation locations for AEDs. Our model is based on two AED conveyance modes, walking/running and driving, involving service distances of 100 and 300 meters, respectively. Our results suggest different AED allocation strategies involving convenience stores in urban settings. In commercial areas, such installations can compensate for temporal gaps in EMS locations when responding to nighttime OHCA incidents. In residential areas, store installations can compensate for long distances from fire stations, where AEDs are currently held in Taipei.

  8. Taxonomic review on the subgenus Tripodura Townes (Diptera: Chironomidae: Polypedilum) from China with eleven new species and a supplementary world checklist.

    Science.gov (United States)

    Zhang, Ruilei; Song, Chao; Qi, Xin; Wang, Xinhua

    2016-07-05

    The subgenus Tripodura Townes of Polypedilum Kieffer from China including 26 species is reviewed. Eleven new species, named P. (T.) absensilobum Zhang & Wang sp. n., P. (T.) apiculusetosum Zhang & Wang sp. n., P. (T.) arcuatum Zhang & Wang sp. n., P. (T.) bilamella Zhang & Wang sp. n., P. (T.) conghuaense Zhang & Wang sp. n., P. (T.) dengae Zhang & Wang sp. n., P. (T.) mengmanense Zhang & Wang sp. n., P. (T.) napahaiense Zhang & Wang sp. n., P. (T.) parallelum Zhang & Wang sp. n., P. (T.) pollicium Zhang & Wang sp. n. and P. (T.) trapezium Zhang & Wang sp. n. are described and illustrated based on male imagines. Three species, P. (T.) quadriguttatum Kieffer, P. (T.) unifascia (Tokunaga) and P. (T.) udominutum Niitsuma are firstly recorded in China. A key to known male imagines of Chinese species and an updated world checklist of subgenus Tripodura are presented.

  9. Implementation of a non-lethal biopsy punch monitoring program for mercury in smallmouth bass, Micropterus dolomieu Lacepède, from the Eleven Point River, Missouri

    Science.gov (United States)

    Ackerson, J.R.; Schmitt, C. J.; McKee, M.J.; Brumbaugh, W.G.

    2013-01-01

    A non-lethal biopsy method for monitoring mercury (Hg) concentrations in smallmouth bass (Micropterus dolomieu; smallmouth) from the Eleven Point River in southern Missouri USA was evaluated. A biopsy punch was used to remove a muscle tissue plug from the area immediately below the anterior dorsal fin of 31 smallmouth. An additional 35 smallmouth (controls) were held identically except that no tissue plug was removed. After sampling, all fish were held in a concrete hatchery raceway for 6 weeks. Mean survival at the end of the holding period was 97 % for both groups. Smallmouth length, weight and Fulton’s condition factor at the end of the holding period were also similar between plugged and non-plugged controls, indicating that the biopsy procedure had minimal impact on growth under these conditions. Tissue plug Hg concentrations were similar to smallmouth Hg data obtained in previous years by removing the entire fillet for analysis.

  10. Implementation of a non-lethal biopsy punch monitoring program for mercury in smallmouth bass, Micropterus dolomieu Lacepede, from the Eleven Point River, Missouri

    Science.gov (United States)

    Ackerson, R.J.; McKee, J.M.; Schmitt, C.J.; Brumbaugh, William G.

    2014-01-01

    A non-lethal biopsy method for monitoring mercury (Hg) concentrations in smallmouth bass (Micropterus dolomieu; smallmouth) from the Eleven Point River in southern Missouri USA was evaluated. A biopsy punch was used to remove a muscle tissue plug from the area immediately below the anterior dorsal fin of 31 smallmouth. An additional 35 smallmouth (controls) were held identically except that no tissue plug was removed. After sampling, all fish were held in a concrete hatchery raceway for 6 weeks. Mean survival at the end of the holding period was 97 % for both groups. Smallmouth length, weight and Fulton’s condition factor at the end of the holding period were also similar between plugged and non-plugged controls, indicating that the biopsy procedure had minimal impact on growth under these conditions. Tissue plug Hg concentrations were similar to smallmouth Hg data obtained in previous years by removing the entire fillet for analysis.

  11. Revision of Thisiomorphus Pic (Coleoptera: Mycteridae: Eurypinae) with descriptions of eleven new species from Central and South America and a key to genera of Neotropical Eurypinae.

    Science.gov (United States)

    Pollock, Darren A

    2016-03-22

    The Neotropical eurypine genus Thisiomorphus is revised, based on external structural features of adults. Twelve species are recognized, including the following eleven new species (type areas in parentheses): T. festivus (Panama, Colón Prov.), T. osaensis (Costa Rica, Puntarenas Prov.), T. davidsoni (Brazil, Chapada), T. inaequalis (Ecuador, Napo Prov.), T. caeruleus (Panama, Panamá Prov.), T. brasiliensis (Brazil, Amazonas), T. solisi (Costa Rica, Guanacaste Prov.), T. andrewsi (Panama, Chiriquí Prov.), T. bolivianus (Bolivia, Santa Cruz Dept.), T. curticornis (Ecuador, Sucumbíos Prov.), and T. convergens (Brazil, Pará). A key to the 13 described eurypine genera of Central and South American is provided, along with a key to species of Thisiomorphus. The keys are supplemented with images of habitus and selected structural features, and maps of known distributions are provided.

  12. Comparison between the mainstream smoke of eleven RYO tobacco brands and the reference tobacco 3R4F

    Directory of Open Access Journals (Sweden)

    A. Marcilla

    2014-01-01

    Full Text Available In this study 11 commercial roll-your-own (RYO tobacco brands sold in Spain and the reference tobacco 3R4F have been smoked and several components of the mainstream tobacco smoke have been analyzed. Cigarettes were prepared using commercial tubes, and were smoked under smoking conditions based on the ISO 3308. The gaseous and condensed fractions of the smoke from RYO brands and 3R4F have been analyzed and compared. RYO tobaccos, as opposed to 3R4F, present lower amounts of condensed products in the traps than in the filters. In general, RYO tobaccos also provide lower yields of most of the compounds detected in the gas fraction. The yield of CO is between 15.4 and 20.4 mg/cigarette. In most of the cases studied, RYO tobaccos deliver higher amounts of nicotine than the 3R4F tobacco. On average, the yield of the different chemical families of compounds appearing in the particulate matter retained in the cigarette filters tends to be around three times higher than those obtained from 3R4F, whereas similar values have been obtained in the particulate matter retained in the traps located after the filters. It can be concluded that RYO tobaccos are not less hazardous than the reference tobacco, which may be contrary to popular belief.

  13. Chromosome Mapping of 18S Ribosomal RNA Genes in Eleven Hypostomus Species (Siluriformes, Loricariidae): Diversity Analysis of the Sites.

    Science.gov (United States)

    Rubert, Marceléia; da Rosa, Renata; Zawadzki, Claudio H; Mariotto, Sandra; Moreira-Filho, Orlando; Giuliano-Caetano, Lucia

    2016-08-01

    We investigated the chromosomal distribution of 18S ribosomal DNA (rDNA) in different populations of 11 species of Hypostomus collected in important Brazilian basins, namely South Atlantic, Upper Paraná, and Paraguay applying the fluorescence in situ hybridization (FISH). Hypostomus cochliodon, Hypostomus commersoni, Hypostomus hermanni, Hypostomus regani, Hypostomus albopunctatus, Hypostomus paulinus, Hypostomus aff. paulinus, Hypostomus iheringii, and Hypostomus mutucae presented multiple 18S rDNA sites while Hypostomus strigaticeps and Hypostomus nigromaculatus exhibited a single pair of chromosomes with 18S rDNA sites. The studied species presented variations in the number and position of these sites. The results accomplished were similar to those obtained by the analysis of AgNORs, revealing the same interspecific variability. Each species exhibited distinctive patterns of AgNOR and 18S rDNA distribution, which can be considered cytogenetic markers in each species of the genus and help improve the discussions on the phylogeny of the group.

  14. Methodology for the development of normative data for ten Spanish-language neuropsychological tests in eleven Latin American countries.

    Science.gov (United States)

    Guàrdia-Olmos, Joan; Peró-Cebollero, Maribel; Rivera, Diego; Arango-Lasprilla, Juan Carlos

    2015-01-01

    Within the field of neuropsychology, there is a significant lack of normative data for individuals in Latin America. To describe the methodology utilized to obtain the data and create norms for 10 Spanish-language neuropsychological tests administered in 11 Latin-American countries in a sample of 3,977 healthy individuals between the ages 18 and 90. The same data manipulation process was applied to the data collected (regardless of the scale or country) using a regression-based procedure that takes into account sex, age, and educational influences on neuropsychological test scores. Following this procedure, we were able to generate age, education, and sex (if relevant) based norms for each test in each of the 11 countries studied. These norms are presented in the 10 articles that comprise this special issue.

  15. Eleven years of malaria surveillance in a Sudanese village highlights unexpected variation in individual disease susceptibility and outbreak severity

    DEFF Research Database (Denmark)

    Creasey, A; Giha, H; Hamad, A A;

    2004-01-01

    An analysis is presented of continuous data collected over 11 years based on 1,902,600 person/days of observation on the malaria experience of the people of Daraweesh, a village in eastern Sudan. Malaria transmission is hypo-endemic: the acquisition of clinical immunity with age is not as obvious...... as in more holo-endemic areas and malaria remained a problem in all age groups throughout the study. However, this population, who are of Fulani origin, showed a distinctly variable level of disease susceptibility. Thirty-two percent of the village never reported malaria symptoms or required malaria...... an interesting question for malaria modelling in this, and in other low transmission zones, such as the burgeoning urban areas of modern Africa....

  16. Eleven-Week Preparation Involving Polarized Intensity Distribution Is Not Superior to Pyramidal Distribution in National Elite Rowers

    Science.gov (United States)

    Treff, Gunnar; Winkert, Kay; Sareban, Mahdi; Steinacker, Jürgen M.; Becker, Martin; Sperlich, Billy

    2017-01-01

    Polarized (POL) training intensity distribution (TID) emphasizes high-volume low-intensity exercise in zone (Z)1 (second lactate threshold) compared to Z2 (between first and second lactate threshold). In highly trained rowers there is a lack of prospective controlled evidence whether POL is superior to pyramidal (PYR; i.e., greater volume in Z1 vs. Z2 vs. Z3) TID. The aim of the study was to compare the effect of POL vs. PYR TID in rowers during an 11-wk preparation period. Fourteen national elite male rowers participated (age: 20 ± 2 years, maximal oxygen uptake (V˙O2max): 66 ± 5 mL/min/kg). The sample was split into PYR and POL by varying the percentage spent in Z2 and Z3 while Z1 was clamped to ~93% and matched for total and rowing volume. Actual TIDs were based on time within heart rate zones (Z1 and Z2) and duration of Z3-intervals. The main outcome variables were average power in 2,000 m ergometer-test (P2,000 m), power associated with 4 mmol/L [blood lactate] (P4[BLa]), and V˙O2max. To quantify the level of polarization, we calculated a Polarization-Index as log (%Z1 × %Z3 / %Z2). PYR and POL did not significantly differ regarding rowing or total volume, but POL had a higher percentage of Z3 intensities (6 ± 3 vs. 2 ± 1%; p superior to PYR, possibly due to the high and very similar percentage of Z1 in this study. PMID:28824440

  17. Rediscovering medicinal plants' potential with OMICS: microsatellite survey in expressed sequence tags of eleven traditional plants with potent antidiabetic properties.

    Science.gov (United States)

    Sahu, Jagajjit; Sen, Priyabrata; Choudhury, Manabendra Dutta; Dehury, Budheswar; Barooah, Madhumita; Modi, Mahendra Kumar; Talukdar, Anupam Das

    2014-05-01

    Herbal medicines and traditionally used medicinal plants present an untapped potential for novel molecular target discovery using systems science and OMICS biotechnology driven strategies. Since up to 40% of the world's poor people have no access to government health services, traditional and folk medicines are often the only therapeutics available to them. In this vein, North East (NE) India is recognized for its rich bioresources. As part of the Indo-Burma hotspot, it is regarded as an epicenter of biodiversity for several plants having myriad traditional uses, including medicinal use. However, the improvement of these valuable bioresources through molecular breeding strategies, for example, using genic microsatellites or Simple Sequence Repeats (SSRs) or Expressed Sequence Tags (ESTs)-derived SSRs has not been fully utilized in large scale to date. In this study, we identified a total of 47,700 microsatellites from 109,609 ESTs of 11 medicinal plants (pineapple, papaya, noyontara, bitter orange, bermuda brass, ratalu, barbados nut, mango, mulberry, lotus, and guduchi) having proven antidiabetic properties. A total of 58,159 primer pairs were designed for the non-redundant 8060 SSR-positive ESTs and putative functions were assigned to 4483 unique contigs. Among the identified microsatellites, excluding mononucleotide repeats, di-/trinucleotides are predominant, among which repeat motifs of AG/CT and AAG/CTT were most abundant. Similarity search of SSR containing ESTs and antidiabetic gene sequences revealed 11 microsatellites linked to antidiabetic genes in five plants. GO term enrichment analysis revealed a total of 80 enriched GO terms widely distributed in 53 biological processes, 17 molecular functions, and 10 cellular components associated with the 11 markers. The present study therefore provides concrete insights into the frequency and distribution of SSRs in important medicinal resources. The microsatellite markers reported here markedly add to the genetic

  18. Force-time curve characteristics and hormonal alterations during an eleven-week training period in elite women weightlifters.

    Science.gov (United States)

    Haff, G Gregory; Jackson, Janna R; Kawamori, Naoki; Carlock, Jon M; Hartman, Michael J; Kilgore, J Lon; Morris, Robert T; Ramsey, Michael W; Sands, William A; Stone, Michael H

    2008-03-01

    The purpose of this investigation was to study the effects of an 11-week training period performed by female weightlifters. Two weeks before this investigation, baseline measures for total testosterone, cortisol, and testosterone:cortisol ratio were collected. The 11-week training program consisted of the core exercises (i.e., clean, clean and jerk, and snatch) and other supplemental exercises (i.e., clean pull, snatch pull, squat, and front squat). Hormonal, isometric, and dynamic middle thigh pull force-time curve characteristics were assessed biweekly throughout the duration of the investigation, whereas volume load and training intensity were assessed weekly throughout the investigation. The testosterone:cortisol ratio of the baseline (1.19 +/- 0.64) was significantly different from the ratio of weeks 1 (0.67 +/- 0.36) and 9 (0.94 +/- 0.66). When the week-to-week values were compared, week 1 (0.67 +/- 0.36) was significantly different (P < 0.05; eta = 0.84) from week 3 (1.06 +/- 0.54). A very strong correlation (r = -0.83; r = 0.69) was found between the percentage change of the testosterone:cortisol ratio and volume load from weeks 1 to 11. Moderate to very strong correlations were noted between the percentage change in volume load and isometric peak force, peak force during the 30% isometric peak force trial, and peak force during the 100-kg trial during the 11 weeks of training. The primary finding of this study was that alterations in training volume load can result in concomitant changes in the anabolic-to-catabolic balance, as indicated by the testosterone:cortisol ratio, and the ability to generate maximal forces.

  19. Association of eleven common, low-penetrance colorectal cancer susceptibility genetic variants at six risk loci with clinical outcome.

    Directory of Open Access Journals (Sweden)

    Janelle M Hoskins

    Full Text Available BACKGROUND: Low-penetrance genetic variants have been increasingly recognized to influence the risk of tumor development. Risk variants for colorectal cancer (CRC have been mapped to chromosome positions 8q23.3, 8q24, 9p24.1, 10p14, 11q23, 14q22.2, 15q13, 16q22.1, 18q21, 19q13.1 and 20p12.3. In particular, the 8q24 single nucleotide polymorphism (SNP, rs6983267, has reproducibly been associated with the risk of developing CRC. As the CRC risk SNPs may also influence disease outcome, thus in this study, we evaluated whether they influence patient survival. METHODOLOGY/PRINCIPAL FINDINGS: DNA samples from 583 CRC patients enrolled in the prospective, North Carolina Cancer Care Outcomes Research and Surveillance Consortium Study (NC CanCORS were genotyped for 11 CRC susceptibility SNPs at 6 CRC risk loci. Relationships between genotypes and patient survival were examined using Cox regression analysis. In multivariate analysis, patients homozygous for the CRC risk allele of rs7013278 or rs7014346 (both at 8 q24 were only nominally significant for poorer overall survival compared to patients homozygous for the protective allele (hazard ratio = 2.20 and 1.96, respectively; P<0.05. None of these associations, however, remained statistically significant after correction for multiple testing. The other nine susceptibility SNPs tested were not significantly associated with survival. CONCLUSIONS/SIGNIFICANCE: We did not find evidence of association of CRC risk variants with patient survival.

  20. Harmonization of the Volume of Interest Delineation among All Eleven Radiotherapy Centers in the North of France.

    Directory of Open Access Journals (Sweden)

    David Pasquier

    Full Text Available Inter-observer delineation variation has been detailed for many years in almost every tumor location. Inadequate delineation can impair the chance of cure and/or increase toxicity. The aim of our original work was to prospectively improve the homogeneity of delineation among all of the senior radiation oncologists in the Nord-Pas de Calais region, irrespective of the conditions of practice.All 11 centers were involved. The first studied cancer was prostate cancer. Three clinical cases were studied: a low-risk prostate cancer case (case 1, a high-risk prostate cancer case (pelvic nodes, case 2 and a case of post-operative biochemical elevated PSA (case 3. All of the involved physicians delineated characteristically the clinical target volume (CTV and organs at risk. The volumes were compared using validated indexes: the volume ratio (VR, common and additional volumes (CV and AV, volume overlap (VO and Dice similarity coefficient (DSC. A second delineation of the same three cases was performed after discussion of the slice results and the choice of shared guidelines to evaluate homogenization. A comparative analysis of the indexes before and after discussion was conducted using the Wilcoxon test for paired samples. A p-value less than 0.05 was considered to indicate statistical significance.The indexes were not improved in case 1, for which the inter-observer agreement was considered good after the first comparison (DSC = 0.83 ± 0.06. In case 2, the second comparison showed homogenization of the CTV delineation with a significant improvement in CV (81.4 ± 11.7 vs. 88.6 ± 10.26, respectively, p = 0.048, VO (0.41 ± 0.09 vs. 0.47 ± 0.07, respectively; p = 0.009 and DSC (0.58 ± 0.09 vs. 0.63 ± 0.07, respectively; p = 0.0098. In case 3, VR and AV were significantly improved: VR: 1.71(± 0.6 vs. 1.34(± 0.46, respectively, p = 0.0034; AV: 46.58(± 14.50 vs. 38.08(± 15.10, respectively, p = 0.0024. DSC was not improved, but it was already

  1. Clinical, immunological and genetic features in eleven Algerian patients with major histocompatibility complex class II expression deficiency

    Directory of Open Access Journals (Sweden)

    Djidjik Réda

    2012-08-01

    Full Text Available Abstract Presenting processed antigens to CD4+ lymphocytes during the immune response involves major histocompatibility complex class II molecules. MHC class II genes transcription is regulated by four transcription factors: CIITA, RFXANK, RFX5 and RFXAP. Defects in these factors result in major histocompatibility complex class II expression deficiency, a primary combined immunodeficiency frequent in North Africa. Autosomal recessive mutations in the RFXANK gene have been reported as being the principal defect found in North African patients with this disorder. In this paper, we describe clinical, immunological and genetic features of 11 unrelated Algerian patients whose monocytes display a total absence of MHC class II molecules. They shared mainly the same clinical picture which included protracted diarrhoea and respiratory tract recurrent infections. Genetic analysis revealed that 9 of the 11 patients had the same RFXANK founder mutation, a 26 bp deletion (named I5E6-25_I5E6+1, also known as 752delG26. Immunological and genetic findings in our series may facilitate genetic counselling implementation for Algerian consanguineous families. Further studies need to be conducted to determine 752delG26 heterozygous mutation frequency in Algerian population.

  2. Clinical, immunological and genetic features in eleven Algerian patients with major histocompatibility complex class II expression deficiency.

    Science.gov (United States)

    Djidjik, Réda; Messaoudani, Nesrine; Tahiat, Azzedine; Meddour, Yanis; Chaib, Samia; Atek, Aziz; Khiari, Mohammed Elmokhtar; Benhalla, Nafissa Keltoum; Smati, Leila; Bensenouci, Abdelatif; Baghriche, Mourad; Ghaffor, Mohammed

    2012-08-03

    Presenting processed antigens to CD4+ lymphocytes during the immune response involves major histocompatibility complex class II molecules. MHC class II genes transcription is regulated by four transcription factors: CIITA, RFXANK, RFX5 and RFXAP. Defects in these factors result in major histocompatibility complex class II expression deficiency, a primary combined immunodeficiency frequent in North Africa. Autosomal recessive mutations in the RFXANK gene have been reported as being the principal defect found in North African patients with this disorder. In this paper, we describe clinical, immunological and genetic features of 11 unrelated Algerian patients whose monocytes display a total absence of MHC class II molecules. They shared mainly the same clinical picture which included protracted diarrhoea and respiratory tract recurrent infections. Genetic analysis revealed that 9 of the 11 patients had the same RFXANK founder mutation, a 26 bp deletion (named I5E6-25_I5E6+1, also known as 752delG26). Immunological and genetic findings in our series may facilitate genetic counselling implementation for Algerian consanguineous families. Further studies need to be conducted to determine 752delG26 heterozygous mutation frequency in Algerian population.

  3. Cross-scale intercomparison of climate change impacts simulated by regional and global hydrological models in eleven large river basins

    Energy Technology Data Exchange (ETDEWEB)

    Hattermann, F. F.; Krysanova, V.; Gosling, S. N.; Dankers, R.; Daggupati, P.; Donnelly, C.; Flörke, M.; Huang, S.; Motovilov, Y.; Buda, S.; Yang, T.; Müller, C.; Leng, G.; Tang, Q.; Portmann, F. T.; Hagemann, S.; Gerten, D.; Wada, Y.; Masaki, Y.; Alemayehu, T.; Satoh, Y.; Samaniego, L.

    2017-01-04

    Ideally, the results from models operating at different scales should agree in trend direction and magnitude of impacts under climate change. However, this implies that the sensitivity of impact models designed for either scale to climate variability and change is comparable. In this study, we compare hydrological changes simulated by 9 global and 9 regional hydrological models (HM) for 11 large river basins in all continents under reference and scenario conditions. The foci are on model validation runs, sensitivity of annual discharge to climate variability in the reference period, and sensitivity of the long-term average monthly seasonal dynamics to climate change. One major result is that the global models, mostly not calibrated against observations, often show a considerable bias in mean monthly discharge, whereas regional models show a much better reproduction of reference conditions. However, the sensitivity of two HM ensembles to climate variability is in general similar. The simulated climate change impacts in terms of long-term average monthly dynamics evaluated for HM ensemble medians and spreads show that the medians are to a certain extent comparable in some cases with distinct differences in others, and the spreads related to global models are mostly notably larger. Summarizing, this implies that global HMs are useful tools when looking at large-scale impacts of climate change and variability, but whenever impacts for a specific river basin or region are of interest, e.g. for complex water management applications, the regional-scale models validated against observed discharge should be used.

  4. Interactive effects of elevated C02 and temperature on the anatomical characteristics of leaves in eleven species

    Institute of Scientific and Technical Information of China (English)

    HAN Mei; JI Chengjun; ZUO Wenyun; HE Jinsheng

    2007-01-01

    The anatomical features of leaves in 11 species of plants grown in a temperature gradient and a temperature + CO2 gradient were studied.The palisade parenchyma thickness,the spongy parenchyma thickness and the total leaf thickness were measured and analyzed to investigate the effects of elevated temperature and CO2 on the anatomical characteristics of the leaves.Our results show that with the increase of temperature,the leaf thickness of C4 species increased while the leaf thickness of C3 species showed no constant changes.With increased CO2,seven out of nine C3 species exhibited increased total leaf thickness.In C4 species,leaf thickness decreased.As for the trend on the multi-grades,the plants exhibited linear or non-linear changes.With the increase of temperature or both temperature and CO2 for the 11 species investigated,leaf thickness varied greatly in different plants (species) and even in different branches on the same plant.These results demonstrated that the effect of increasing CO2 and temperature on the anatomical features of the leaves were species-specific.Since plant structures are correlated with plant functions,the changes in leaf anatomical characteristics in elevated temperature and CO2 may lead to functional differences.

  5. Eleven-Week Preparation Involving Polarized Intensity Distribution Is Not Superior to Pyramidal Distribution in National Elite Rowers

    Directory of Open Access Journals (Sweden)

    Gunnar Treff

    2017-08-01

    Full Text Available Polarized (POL training intensity distribution (TID emphasizes high-volume low-intensity exercise in zone (Z1 (< first lactate threshold with a greater proportion of high-intensity Z3 (>second lactate threshold compared to Z2 (between first and second lactate threshold. In highly trained rowers there is a lack of prospective controlled evidence whether POL is superior to pyramidal (PYR; i.e., greater volume in Z1 vs. Z2 vs. Z3 TID. The aim of the study was to compare the effect of POL vs. PYR TID in rowers during an 11-wk preparation period. Fourteen national elite male rowers participated (age: 20 ± 2 years, maximal oxygen uptake (V˙O2max: 66 ± 5 mL/min/kg. The sample was split into PYR and POL by varying the percentage spent in Z2 and Z3 while Z1 was clamped to ~93% and matched for total and rowing volume. Actual TIDs were based on time within heart rate zones (Z1 and Z2 and duration of Z3-intervals. The main outcome variables were average power in 2,000 m ergometer-test (P2,000 m, power associated with 4 mmol/L [blood lactate] (P4[BLa], and V˙O2max. To quantify the level of polarization, we calculated a Polarization-Index as log (%Z1 × %Z3 / %Z2. PYR and POL did not significantly differ regarding rowing or total volume, but POL had a higher percentage of Z3 intensities (6 ± 3 vs. 2 ± 1%; p < 0.005 while Z2 was lower (1 ± 1 vs. 3 ± 2%; p < 0.05 and Z1 was similar (94 ± 3 vs. 93 ± 2%, p = 0.37. Consequently, Polarization-Index was significantly higher in POL (3.0 ± 0.7 vs. 1.9 ± 0.4 a.u.; p < 0.01. P2,000 m did not significantly change with PYR (1.5 ± 1.7%, p = 0.06 nor POL (1.5 ± 2.6%, p = 0.26. V˙O2max did not change (1.7 ± 5.6%, p = 0.52 or 0.6 ± 2.6, p = 0.67 and a small increase in P4[BLa] was observed in PYR only (1.9 ± 4.8%, p = 0.37 or −0.5 ± 4.1%, p = 0.77. Changes from pre to post were not significantly different between groups in any performance measure. POL did not prove to be superior to PYR, possibly due to

  6. Metastasectomía pulmonar: experiencia de once años Lung metastasectomy: experience of eleven years

    Directory of Open Access Journals (Sweden)

    Bárbaro Agustín Armas Pérez

    2009-03-01

    Full Text Available INTRODUCCIÓN. Las metástasis pulmonares son frecuentes tanto en tumores primarios epiteliales como en los mesenquimatosos, y se explican por el hecho de que todo el gasto cardíaco transita por la circulación menor. La indicación quirúrgica es un problema de relación costo-beneficio y está condicionada entre otros aspectos por el intervalo libre de enfermedad, el estado general del paciente, el número de metástasis y el tipo de resección. El objetivo del presente estudio fue presentar nuestra experiencia y resultados con dicho tratamiento. MÉTODOS. Se realizó un estudio descriptivo transversal retrospectivo con 6 pacientes con metástasis en pulmón, tratados en el Hospital «Amalia Simoni», de Camagüey, entre 1997 y 2007. Las variables analizadas fueron sexo, edad, histopatología y localización del tumor primario, operación inicial, tiempo transcurrido entre la operación inicial y la metastasectomía, número de metástasis pre y transoperatorias, vía de abordaje, localización de los nódulos, tipo de resección quirúrgica y supervivencia. RESULTADOS. La media de edad fue de 56 años y no hubo diferencias en cuanto al sexo. En tres pacientes las tumoraciones primarias dependían del sistema digestivo, la mayoría fueron nódulos únicos y la lobectomía pulmonar fue el procedimiento más utilizado. La supervivencia promedio fue de 13 meses. No hubo morbilidad importante, ni fallecidos en la serie.INTRODUCTION. Lung metastases are frequent both in primary epithelial tumors and mesenchymatous tumors due to the fact that the whole cardiac output passes through the minor circulation. The surgical indication is a problem of cost-benefit relationship, and it is conditioned among other aspects by the disease free interval, the general state of the patient, the number of metastases and the type of resection. The objective of this study was to present our experience and results with this treatment. METHODS. A descriptive cross

  7. Seroprevalence of Trypanosoma cruzi among eleven potential reservoir species from six states across the southern United States.

    Science.gov (United States)

    Brown, Emily L; Roellig, Dawn M; Gompper, Matthew E; Monello, Ryan J; Wenning, Krista M; Gabriel, Mourad W; Yabsley, Michael J

    2010-10-01

    Trypanosoma cruzi, the causative agent of Chagas' disease, is a substantial public health concern in Latin America. Although rare in humans and domestic animals in the United States, T. cruzi is commonly detected in some wildlife species, most commonly raccoons (Procyon lotor) and Virginia opossums (Didelphis virginiana). To increase our understanding of the reservoir host species range and geographic distribution, 11 species of mammals from six states spanning the known range of T. cruzi (Arizona, California, Florida, Georgia, Missouri, and Virginia) were tested for antibodies to T. cruzi using indirect immunofluorescent antibody testing. In addition, culture isolation attempts were conducted on a limited number of animals from Georgia and Florida. Evidence of T. cruzi was found in every state except California; however, low numbers of known reservoirs were tested in California. In general, the highest seroprevalence rates were found in raccoons (0-68%) and opossums (17-52%), but antibodies to T. cruzi were also detected in small numbers of striped skunks (Mephitis mephitis) from Arizona and Georgia, bobcats (Lynx rufus) from Georgia, two coyotes (Canis latrans) from Georgia and Virginia, and a ringtail (Bassariscus astutus) from Arizona. Culture-based prevalence rates for raccoons were significantly greater than those for opossums; however, seroprevalences of raccoons and opossums from several geographic locations in Georgia and Florida were not different, indicating that exposure rates of these two species are similar within these areas. For both raccoons and opossums, seroprevalence was significantly higher in females than in males. No difference was detected in seroprevalence between adults and juveniles and between animals caught in urban and rural locations. Our results indicate that T. cruzi prevalence varies by host species, host characteristics, and geographic region and provides data to guide future studies on the natural history of T. cruzi in the

  8. Cross - Scale Intercomparison of Climate Change Impacts Simulated by Regional and Global Hydrological Models in Eleven Large River Basins

    Science.gov (United States)

    Hattermann, F. F.; Krysanova, V.; Gosling, S. N.; Dankers, R.; Daggupati, P.; Donnelly, C.; Florke, M.; Huang, S.; Motovilov, Y.; Buda, S.; Wada, Y.

    2017-01-01

    Ideally, the results from models operating at different scales should agree in trend direction and magnitude of impacts under climate change. However, this implies that the sensitivity to climate variability and climate change is comparable for impact models designed for either scale. In this study, we compare hydrological changes simulated by 9 global and 9 regional hydrological models (HM) for 11 large river basins in all continents under reference and scenario conditions. The foci are on model validation runs, sensitivity of annual discharge to climate variability in the reference period, and sensitivity of the long-term average monthly seasonal dynamics to climate change. One major result is that the global models, mostly not calibrated against observations, often show a considerable bias in mean monthly discharge, whereas regional models show a better reproduction of reference conditions. However, the sensitivity of the two HM ensembles to climate variability is in general similar. The simulated climate change impacts in terms of long-term average monthly dynamics evaluated for HM ensemble medians and spreads show that the medians are to a certain extent comparable in some cases, but have distinct differences in other cases, and the spreads related to global models are mostly notably larger. Summarizing, this implies that global HMs are useful tools when looking at large-scale impacts of climate change and variability. Whenever impacts for a specific river basin or region are of interest, e.g. for complex water management applications, the regional-scale models calibrated and validated against observed discharge should be used.

  9. Eleven cities Solar boat challenge

    NARCIS (Netherlands)

    Verdult, E.

    2012-01-01

    TU Delft students are participating for the fourth time in the world championship solar boat race in Friesland, which begins on 8 July. Expectations are high because the TU Delft students were world champions in 2006 and 2008. In 2010, the solar boat was equipped with hydrofoils for the first time.

  10. Eleven Ways To Make Money.

    Science.gov (United States)

    Vail, Kathleen

    1998-01-01

    Many school districts are becoming aggressively entrepreneurial in their efforts to raise money. One district serves as the Internet service provider for their area, another rents buses and drivers to community groups. A sidebar describes a controversial deal between Coca-Cola and the Colorado Springs School District. (MLF)

  11. Eleven papers on differential equations

    CERN Document Server

    Akhmedov, S A; Berezanskii, Yu M; Bazalii, B V; Berezanskii, Yu M

    1985-01-01

    The papers in this volume, like those in the previous one, have been selected, translated, and edited from publications not otherwise translated into English under the auspices of the AMS-ASL-IMS Committee on Translations from Russian and Other Foreign Languages.

  12. Report on the Medicinal Use of Eleven Lamiaceae Species in Lebanon and Rationalization of Their Antimicrobial Potential by Examination of the Chemical Composition and Antimicrobial Activity of Their Essential Oils

    Science.gov (United States)

    Khoury, Madona; Eparvier, Véronique; Ouaini, Naïm

    2016-01-01

    Many Lamiaceae species are consumed in the Lebanese cuisine as food or condiment and are largely used in the traditional medicine of Lebanon to treat various diseases, including microbial infections. In this article we report the traditional medicinal uses of eleven Lamiaceae species: Coridothymus capitatus L., Lavandula stoechas L., Lavandula angustifolia Mill., Mentha spicata L. subsp. condensata, Origanum syriacum L., Rosmarinus officinalis, Salvia fruticosa Miller., Satureja cuneifolia Ten., Satureja thymbra L., Thymbra spicata L., and Vitex agnus-castus L. and study the chemical composition and antimicrobial activity of their essential oils (EOs). Our survey showed that Lamiaceae species are mainly used against gastrointestinal disorders and microbial infections. Chemical analysis of the EOs obtained from these plants allowed us to identify seventy-five compounds describing more than 90% of the relative composition of each EO. Essential oils with high amounts of thymol and carvacrol possessed the strongest antimicrobial activity. As expected, these two compounds demonstrated an interesting antifungal efficacy against the filamentous fungus T. rubrum. Our results confirmed that some of the Lamiaceae species used in Lebanon ethnopharmacological practices as antimicrobial agents do possess antibacterial and antifungal potential consistent with their use in alternative or complementary medicine. PMID:28053641

  13. Report on the Medicinal Use of Eleven Lamiaceae Species in Lebanon and Rationalization of Their Antimicrobial Potential by Examination of the Chemical Composition and Antimicrobial Activity of Their Essential Oils

    Directory of Open Access Journals (Sweden)

    Madona Khoury

    2016-01-01

    Full Text Available Many Lamiaceae species are consumed in the Lebanese cuisine as food or condiment and are largely used in the traditional medicine of Lebanon to treat various diseases, including microbial infections. In this article we report the traditional medicinal uses of eleven Lamiaceae species: Coridothymus capitatus L., Lavandula stoechas L., Lavandula angustifolia Mill., Mentha spicata L. subsp. condensata, Origanum syriacum L., Rosmarinus officinalis, Salvia fruticosa Miller., Satureja cuneifolia Ten., Satureja thymbra L., Thymbra spicata L., and Vitex agnus-castus L. and study the chemical composition and antimicrobial activity of their essential oils (EOs. Our survey showed that Lamiaceae species are mainly used against gastrointestinal disorders and microbial infections. Chemical analysis of the EOs obtained from these plants allowed us to identify seventy-five compounds describing more than 90% of the relative composition of each EO. Essential oils with high amounts of thymol and carvacrol possessed the strongest antimicrobial activity. As expected, these two compounds demonstrated an interesting antifungal efficacy against the filamentous fungus T. rubrum. Our results confirmed that some of the Lamiaceae species used in Lebanon ethnopharmacological practices as antimicrobial agents do possess antibacterial and antifungal potential consistent with their use in alternative or complementary medicine.

  14. Taxonomic review of the genera Micridium Motschulsky, 1869 and Micridina Johnson, 1969 (Coleoptera: Ptiliidae) with eleven new species including the first records from South America and Madagascar.

    Science.gov (United States)

    Darby, Michael

    2017-03-10

    The six recognised species of the genus Micridium Motschulsky, 1869: M. vittatum (Motschulsky, 1845) M. halidaii (Matthews, 1868), M. angulicolle (Fairmaire, 1858), M. lineatum (Le Conte, 1863). M. rhodeanum (Casey, 1924) and M. groehni Polilov & Perkovsky, 2004 are reviewed and eleven new species: M. attenboroughi sp.n., M. boliviense sp.n., M. elegans sp. n., M. foveatum sp.n., M. inornatum sp.n., M. johnsoni sp.n., M. newtoni sp.n., M. oweni sp.n., M. proprium sp.n., M. quadridens sp.n. and M. thayerae sp.n. are added. The new species are the first records of the genus from South America and Madagascar. The morphological characteristics separating Micridium from other genera in the tribe Ptiliini are discussed and the genus synonymised with the closely related monotypic genus Micridina Johnson, 1969 with its single species M. hilli Johnson, 1969. The synonymy of Dilinium Casey, 1924 with Micridium is confirmed and the type species D. rhodeanum Casey, 1924 re-described. Micridium groehni, described from a single specimen in Baltic amber, does not appear to belong to Micridium as defined here. A key to the new species is provided.

  15. Optimal Installation Locations for Automated External Defibrillators in Taipei 7-Eleven Stores: Using GIS and a Genetic Algorithm with a New Stirring Operator

    Directory of Open Access Journals (Sweden)

    Chung-Yuan Huang

    2014-01-01

    Full Text Available Immediate treatment with an automated external defibrillator (AED increases out-of-hospital cardiac arrest (OHCA patient survival potential. While considerable attention has been given to determining optimal public AED locations, spatial and temporal factors such as time of day and distance from emergency medical services (EMSs are understudied. Here we describe a geocomputational genetic algorithm with a new stirring operator (GANSO that considers spatial and temporal cardiac arrest occurrence factors when assessing the feasibility of using Taipei 7-Eleven stores as installation locations for AEDs. Our model is based on two AED conveyance modes, walking/running and driving, involving service distances of 100 and 300 meters, respectively. Our results suggest different AED allocation strategies involving convenience stores in urban settings. In commercial areas, such installations can compensate for temporal gaps in EMS locations when responding to nighttime OHCA incidents. In residential areas, store installations can compensate for long distances from fire stations, where AEDs are currently held in Taipei.

  16. Sr fluxes and isotopic compositions of the eleven rivers originating from the Qinghai-Tibet Plateau and their contributions to 87Sr/86Sr evolution of seawater

    Institute of Scientific and Technical Information of China (English)

    WU WeiHua; YANG JieDong; XU ShiJin; LI GaoJun; YIN HongWei; TAO XianCong

    2009-01-01

    To evaluate influence of chemical weathering of the Qinghai-Tibet Plateau (QTP) on seawater 87Sr/66Srvariation, river water and sediment samples were collected, and their Sr concentrations and isotopic compositions analyzed, from the seven large rivers that originated from the QTP. By combining these with the data of the Ganges, Brahmaputra, Indus and Irrawaddy originated in the southern QTP, the total transported by the global rivers. The weighted mean 87Sr/86Sr is 0.71694, higher than the average value of the global rivers. The 87Srex (87Sr flux in excess of the seawater 87Sr/66Sr ratio) of the Chinese seven QTP, and the Ganges-Brahmaputra system accounts for 86%. We assume that the QTP rivers have no strontium contributions to the oceans before -40 Ma and the Sr fluxes of the global rivers, except the QTP eleven rivers, are constant, then a maximum linear increase in Sr fluxes of the QTP rivers from zero to the modern value in response to tectonic uplift can explain -69% increase of seawater 87Sr/86Sr over the past -40 Ma and the remainder of 31% is perhaps provided from other factors.

  17. New Constraints on $\\Omega_M$, $\\Omega_\\Lambda$, and w from an Independent Set of Eleven High-Redshift Supernovae Observed with HST

    CERN Document Server

    Knop, R A; Amanullah, R; Astier, Pierre; Blanc, G; Burns, M S; Conley, A; Deustua, S E; Doi, M; Ellis, R; Fabbro, S; Folatelli, G; Fruchter, A S; Garavini, G; Garmond, S; Garton, K; Gibbons, R; Goldhaber, G; Goobar, A; Groom, D E; Hardin, D; Hook, I; Howell, D A; Kim, A G; Lee Byung Cheol; Lidman, C E; Méndez, J; Nobili, S; Nugent, P; Pain, R; Panagia, N; Pennypacker, C R; Perlmutter, S; Quimby, R; Raux, J; Regnault, N; Ruiz-Lapuente, P; Sainton, G; Schaefer, B; Schahmaneche, K; Smith, E; Spadafora, A L; Stanishev, V; Sullivan, M; Walton, N A; Wang, L; Wood-Vasey, W M; Yasuda, N

    2003-01-01

    We report measurements of $\\Omega_M$, $\\Omega_\\Lambda$, and w from eleven supernovae at z=0.36-0.86 with high-quality lightcurves measured using WFPC-2 on the HST. This is an independent set of high-redshift supernovae that confirms previous supernova evidence for an accelerating Universe. Combined with earlier Supernova Cosmology Project data, the new supernovae yield a flat-universe measurement of the mass density $\\Omega_M=0.25^{+0.07}_{-0.06}$ (statistical) $\\pm0.04$ (identified systematics), or equivalently, a cosmological constant of $\\Omega_\\Lambda=0.75^{+0.06}_{-0.07}$ (statistical) $\\pm0.04$ (identified systematics). When the supernova results are combined with independent flat-universe measurements of $\\Omega_M$ from CMB and galaxy redshift distortion data, they provide a measurement of $w=-1.05^{+0.15}_{-0.20}$ (statistical) $\\pm0.09$ (identified systematic), if w is assumed to be constant in time. The new data offer greatly improved color measurements of the high-redshift supernovae, and hence imp...

  18. Analysis of female characters in Krleža's novel "Na rubu pameti" by example of eleven stereotypes of Mary Ellmann

    Directory of Open Access Journals (Sweden)

    Marina Tkalčić

    2015-06-01

    Full Text Available In this paper the aim is to detect the places which refute allegations of some theorists (like Biljana Oklopčić, Dubravka Oraić Tolić about Miroslav Krleža as a misogynistic author, based on his forming of female characters, in this case, through the example of the novel »Na rubu pameti«. Considering (often neglected antithesis, multidimensionality, and complexity of Krleža's procedures at refining of his characters, this paper makes a conclusion regarding Krleža's exposure of the stereotypical and sexist understanding of womanhood through the usage of ironic acts. Based on this, the paper tries to establish a connection between the formation of female characters in the novel »Na rubu pameti« and the book Thinking About Women by Mary Ellmann. In this book the author suggests usage of the political stereotypes as a strategy for their unmasking. Ellmann, in her book, talks about thinking by using sexual analogies in the western world. The product of such thinking are eleven stereotypes about women processed in the book: formlessness, passivity, instability, confinment, piety, materiality, spirituality, irrationality, complaisance, and »two irreparable figures« – the Shrew and the Witch. Aforementioned stereotypes, in this paper, are used in the forming of feminine psychic cards in the novel »Na rubu pameti«.

  19. Study on Tautology in Eleven Ancient Medical Books%十一部古医籍重言之研究(续)

    Institute of Scientific and Technical Information of China (English)

    崔锡章

    2001-01-01

    @@ 四、在注释中探求重言释义的规律与方法 对十一部古医籍的重言进行准确的释义,是十分困难的事情.因为有的词未被现有的工具书收入;有的词虽然收入字辞典中,但与医籍中所用之义相去甚远;有的词被历代注释者遇难而默,搁置在一边;有的词虽从医理方面可以讲通,但从训诂的角度分析释义不准.要把每一个重言词解释得既符合文理又符合医理,进行精审的诂释是一项浩繁而艰巨的工作.

  20. Patterns of Somatic Diagnoses in Older People with Intellectual Disability: A Swedish Eleven Year Case-Control Study of Inpatient Data

    Science.gov (United States)

    Sandberg, Magnus; Ahlström, Gerd; Kristensson, Jimmie

    2017-01-01

    Background: Knowledge about diagnoses patterns in older people with intellectual disabilities is limited. Methods: The case group (n = 7936) comprised people with intellectual disabilities aged 55 years and older. The control group (n = 7936) was age matched and sex matched. Somatic inpatient diagnoses (2002-2012) were collected retrospectively.…

  1. Eleven-year results on soft and durum wheat crops grown in an organic and in a conventional low input cropping system

    Directory of Open Access Journals (Sweden)

    Paolo Benincasa

    2016-05-01

    Full Text Available Eleven-year results on yields and apparent balances of organic matter and nitrogen (N are reported for soft and durum wheat crops grown in the BIOSYST long-term experiment for the comparison between an organic and a conventional low-input system in Central Italy. The N supply to organic wheat consisted of 40 kg N ha–1 as poultry manure plus the supposed residual N left by green manures carried out before the preceding summer vegetable, while the N supply to conventional wheat consisted of 80 kg N ha–1 as mineral fertilisers, split in two applications of 40 kg ha–1 each, at tillering and pre-shooting. In every year, above ground biomass and N accumulation of each wheat species, including weeds, and the partitioning between grain yield and crop residues were determined. Apparent dry matter and N balances were calculated at the end of each crop cycle by taking into account the amounts of dry matter and N supplied to the system as fertilisers, and those removed with grain yield. Soft wheat yielded more than durum wheat. For both species, grain yield and protein content were more variable across years and generally lower in the organic than in the conventional system. In both systems, grain yield of both species resulted negatively correlated with fall-winter rainfall, likely for its effect on soil N availability. Both species caused a lower return of biomass and a higher soil N depletion in the organic than in the conventional system. Our experiment confirmed that winter wheat can help exploit the soil N availability and reduce N leaching in fall winter, especially after summer vegetables, but in stockless or stock-limited organic systems it needs to be included in rotations where soil fertility is restored by fall winter green manures to be carried out before summer crops.

  2. Simultaneous Determination of Eleven Organic acids in Wines by SPE-HPLC-PAD%高效液相色谱法测定葡萄酒中11种有机酸含量

    Institute of Scientific and Technical Information of China (English)

    杨东伟; 李晓静; 王芬; 李永库

    2013-01-01

    A rapid, sensitive and accurate solid phase extraction reverse phase high performance liquid chromatography-photodiode array detector( SPE-HPLC-PAD) method for simultaneous determination of eleven kinds of organic acids(oxalic acid, acetic acid, crylic acid, succinic acid, malonic acid, tartaric acid, fumaric acid, citric acid, propionic acid, malic acid and lactic acid) in four wines was studied. The analytes were separated by using a Hypersil C18 column(5 μm, 250 mm × 4.6 mm i. d. ) and methanol -0.5% Na2HPO4 as mobile phase with linear gradient elution. The eleven compounds were identified by retention time data and spectral characteristics and quantified by peak area. There were good linear correlations between the concentrations and peak areas of the eight components with the correlation coefficients of 0.996 2~0.999 5. The average recoveries were 85.5% -99.5% with relative standard deviations of 1.2% -4.3% (n = 5). The detection limits were 0.4-2.5 mg/L. The results also showed that it is a convenient, rapid, sensitive and accurate method. It can be used to analyze these organic acids in other complex matrices.%建立了固相萃取-高效液相色谱光电二极管阵列检测法测定葡萄酒中草酸、乙酸、丙烯酸、琥珀酸、丙二酸、酒石酸、富马酸、柠檬酸、丙酸、苹果酸和乳酸11种有机酸的方法,并用此方法测定了市售的4种葡萄酒中11种有机酸的含量.试验采用HypersilC18柱(5μm,250 mm×4.6 mmi.d.)分离,以甲醇-0.5%磷酸为流动相,线性梯度洗脱,以保留时间和特征光谱对分离出的组分予以定性确证,用峰面积进行定量.结果表明,11种有机酸组分的质量浓度与其峰面积在一定的范围内有良好的线性关系,相关系数为0.996 2 ~0.9995,11种组分的平均回收率为85.5% ~99.5%(相对标准偏差为1.2% ~4.3%),检测限为0.4~2.5 mg/L.该方法简便、快速、灵敏,也适用于其他复杂体系中草酸等11种有机酸的成分分析.

  3. Development and validation of a novel stability-indicating HPLC method for the quantitative determination of eleven related substances in ezetimibe drug substance and drug product.

    Science.gov (United States)

    Luo, Zhiqiang; Deng, Zhongqing; Liu, Yang; Wang, Guopeng; Yang, Wenning; Hou, Chengbo; Tang, Minming; Yang, Ruirui; Zhou, Huaming

    2015-07-01

    Ezetimibe is a novel lipid-lowering agent that inhibits intestinal absorption of dietary and biliary cholesterol. In the present work, a simple, sensitive and reproducible gradient reverse phase high performance liquid chromatographic (RP-HPLC) method for separation and determination of the related substances of ezetimibe was developed and validated. Eleven potential process-related impurities (starting materials, (3S,4S,3'S)-isomer, degradants and byproducts) were identified in the crude samples. Tentative structures for all the impurities were assigned primarily based on comparison of their retention time and mass spectrometric data with that of available standards and references. This method can be applied to routine analysis in quality control of both bulk drugs and commercial tablets. Separation of all these compounds was performed on a Phenomenex Luna Phenyl-Hexyl (100mm×4.6mm, 5μm) analytical column. The mobile phase-A consists of acetonitrile-water (pH adjusted to 4.0 with phosphoric acid)-methanol at 15:75:10 (v/v/v), and mobile phase-B contains acetonitrile. The eluted compounds were monitored at 210nm. Ezetimibe was subjected to hydrolytic, acid, base, oxidative, photolytic and thermal stress conditions as per ICH serves to generate degradation products that can be used as a worst case to assess the analytical method performance. The drug showed extensive degradation in thermal, acid, oxidative, base and hydrolytic stress conditions, while it was stable to photolytic degradation conditions. The main degradation product formed under thermal, acid, oxidative, base and hydrolytic stress conditions corresponding to (2R,3R,6S)-N, 6-bis(4-fluorophenyl)-2-(4-hydroxyphenyl)-oxane-3-carboxamide (Ezetimibe tetrahydropyran impurity) was characterized by LC-MS/MS analysis. The degradation products were well resolved from the main peak and its impurities, thus proved the stability-indicating power of the method. The developed method was validated as per

  4. A new multi-gas constrained model of trace gas non-homogeneous transport in firn: evaluation and behavior at eleven polar sites

    Directory of Open Access Journals (Sweden)

    E. Witrant

    2011-08-01

    Full Text Available Insoluble trace gases are trapped in polar ice at the firn-ice transition, at approximately 50 to 100 m below the surface, depending primarily on the site temperature and snow accumulation. Due to the different time scales for snow accumulation versus diffusion of gases through the snowpack, age differences between gases and the ice in which they are "trapped" can be large; e.g. several thousand years in central Antarctica (a low snow accumulation area. Models of trace gas diffusion in polar firn are used to relate firn air and ice core records of trace gases to their atmospheric history. We propose a new diffusion model based on the following contributions. First, the airflow transport model is revised in a poromechanics framework with specific emphasis on the non-homogeneous properties (convective layer, depth-dependent diffusivity and lock-in zone and an almost-stagnant behavior described by Darcy's law (gravity effect. We then derive a non-linear least square multi-gas optimization scheme to calculate the effective firn diffusivity (automatic diffusivity tuning. The improvements associated with the additional constraints gained by the multi-gas approach are investigated (up to eleven gases for a single site are included in the optimization process. The model is applied to measured data from four Arctic (Devon Island, NEEM, North GRIP, Summit and seven Antarctic (DE08, Berkner Island, Siple Dome, Dronning Maud Land, South Pole, Dome C, Vostok sites and the depth-dependent diffusivity profiles are calculated. Among these different sites, a relationship between an increasing thickness of the lock-in zone defined from the isotopic composition of molecular nitrogen in firn air (denoted δ15N and the snow accumulation rate is obtained, in accordance with observations. It is associated with reduced diffusivity depth-gradients in deep firn, which decreases gas density depth-gradients, at high accumulation rate sites. This has implications

  5. 'Check it out!' Decision-making of vulnerable groups about participation in a two-stage cardiometabolic health check: a qualitative study

    NARCIS (Netherlands)

    Groenenberg, I.; Crone, M.R.; Dijk, S. van; Gebhardt, W.A.; Meftah, J. Ben; Middelkoop, B.J.C.; Stiggelbout, A.M.; Assendelft, W.J.

    2015-01-01

    OBJECTIVE: Exploring determinants influencing vulnerable groups regarding (non-) participation in the Dutch two-stage cardiometabolic health check, comprising a health risk assessment (HRA) and prevention consultations (PCs) for high-risk individuals. METHODS: Qualitative study comprising 21 focus

  6. 'Check it out!' Decision-making of vulnerable groups about participation in a two-stage cardiometabolic health check: a qualitative study

    NARCIS (Netherlands)

    Groenenberg, I.; Crone, M.R.; Dijk, S. van; Gebhardt, W.A.; Meftah, J. Ben; Middelkoop, B.J.C.; Stiggelbout, A.M.; Assendelft, W.J.

    2015-01-01

    OBJECTIVE: Exploring determinants influencing vulnerable groups regarding (non-) participation in the Dutch two-stage cardiometabolic health check, comprising a health risk assessment (HRA) and prevention consultations (PCs) for high-risk individuals. METHODS: Qualitative study comprising 21 focus g

  7. Statistic analysis of mossflora between the Mt.Huangshan and other eleven mountains%黄山与11个代表性山区的藓类植物区系统计分析

    Institute of Scientific and Technical Information of China (English)

    吴明开; 张小平; 曹同

    2011-01-01

    The mossfiora was studied by utilizing statistic analysis of two dimensional arrangement of the similarity of the moss flora between the Mt. Huangshan and other eleven mountains in China. The results were agreed with Professor P C Wu's view that original 7 bryological regions of China should be divided into 10 ones according to the distribution of the bryophytes of China,and the authors holded the Mt. Huangshan belonged to the distribution of the bryophytes of the East China region. Depending on the quantitative and qualitative analysis,the authors con sidered that the mossflora of Mt. Huangshan represented the transitional from subtropical region to temperate region in East China.%对黄山与其它11个山区藓类植物区系进行了统计分析比较.从12个山区藓类植物共有属的分析结果来看,黄山是一些典型具有热带性质的属分布北界,同时又是一些典型温带属的分布南界,显示了黄山是热带亚热带向温带、寒温带过渡的典型区域.从极点排序的二维图形分析结果看,黄山与江西的马头山,广西的九万山,浙江的金华山、西天目山关系更为密切;而与湖北的神农架,山东的沂山,河南的云台山关系都比较疏远,反映了黄山的藓类植物具有热带亚热带倾向,支持了吴鹏程等对中国苔藓植物的地理分区的划分,黄山属于华东区,且处于华东区与岭南区的交错地带.

  8. NON-PARTICIPATION BIAS IN HEALTH SERVICES RESEARCH USING DATA FROM AN INTEGRATED ELECTRONIC PRESCRIBING PROJECT: THE ROLE OF INFORMED CONSENT SESGO POR FALTA DE PARTICIPACIÓN EN LA INVESTIGACIÓN DE LOS SERVICIOS DE SALUD AL USAR DATOS DE UN PROYECTO INTEGRADO DE RESCRIPCIÓN ELECTRÓNICA: EL PAPEL DEL CONSENTIMIENTO INFORMADO SESGO PELA FALTA DE PARTICIPAÇÃO NA PESQUISA DOS SERVIÇOS DE SAÚDE AO USAR DADOS DE UM PROJETO INTEGRADO DE PRESCRIÇÃO ELETRÔNICA: O PAPEL DO CONSENTIMENTO INFORMADO

    Directory of Open Access Journals (Sweden)

    Gillian Bartlett

    2005-01-01

    Full Text Available Electronic prescribing potentially reduces adverse outcomes and provides critical information for drug safety research but studies may be distorted by non-participation bias. 52,507 patients and 28 physicians were evaluated to determine characteristics associated with consent status in an electronic prescribing project. Physicians with less technology proficiency, seeing more patients, and having patients with higher fragmentation of care were less likely to obtain consent. Older patients with complex health status, higher income, and more visits to the study physician were more likely to consent. These systematic differences could result in significant non-participation bias for research conducted only with consenting patientsLa prescripción electrónica reduce, potencialmente, los resultados adversos. y proporciona información crítica para una investigación segura en drogas, pero los estudios pueden ser distorsionados por un sesgo por falta de participación. Se evaluó a 52.505 pacientes y a 28 médicos para determinar características asociadas con el estatus del consentimiento en un proyecto de prescripción electrónica. Los médicos con menor eficiencia tecnológica, con más cantidad de pacientes que, además, mostraban mayor fragmentación en su atención, presentaban menor opción de obtener consentimiento. Los pacientes de más edad, con estatus de salud complejo, mayor ingreso y con más visitas al médico a cargo, manifestaban mayor disposición a consentir. Estas diferencias sistemáticas podrían desembocar en un sesgo significativo por falta de participación en la investigación llevada a cabo sólo con pacientes con consentimientoA prescrição eletrônica reduz potencialmente os resultados adversos e proporciona informação crítica para uma pesquisa segura em drogas, porém os estudos podem ser destorcidos por um sesgo por falta de participação. Avaliou-se 52.505 pacientes e a 28 médicos para determinar caracter

  9. Cities, Towns and Villages, Municipal boundaries for an eleven county region (Cumberland, Hoke, Scotland, Richmond, Montgomery, Moore, Lee, Harnett, Sampson, Bladen, Robeson). Data from county or directly from a town/city. Data combined into a single layer., Published in 2007, NC Dept of Commerce - DCA.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Cities, Towns and Villages dataset, was produced all or in part from Other information as of 2007. It is described as 'Municipal boundaries for an eleven county...

  10. Validation of the Benefit Forecasting Method: Organization Development Program to Increase Health Organization Membership. Training and Development Research Center, Project Number Eleven.

    Science.gov (United States)

    Sleezer, Catherine M.; And Others

    This project is the sixth in a series of studies designed to validate the Training and Development Benefit Forecasting Method (BFM) sponsored by the Training and Development Research Center (TDRC) at the University of Minnesota. The purpose of this study was to validate the BFM's ability to forecast the benefits of an organization development…

  11. 大兴沙地中11个树种基于根系形态的适应性%Adaptability of Eleven Tree Species Based on Root Characteristics in Daxing Sandy Land, Beijing

    Institute of Scientific and Technical Information of China (English)

    柴源; 徐程扬; 袁士保; 陈华; 段树生

    2012-01-01

    An experiment was conducted to study the adaptability of 11 tree species in Daxing sandy land in Beijing according to aboveground growth, root vertical distribution, and root morphological variation by means of systematic clustering. Results showed that tree height, diameter at breast height, shoot length, shoot relative growth, root length, root surface area, root volume and specific root length were obviously different among the eleven tree species (p<0.001). Strong differentiation of fine roots was observed in Ailanthus altissima, Catalpa bungei, and relative strong differentiation of fine roots in Gleditsia sinensis, Sabina chinensis and Koelreuteria paniculate, indicating that these tree species were drought resistant by using more soil resources. The drought avoidance of Ziziphus jujuba, Elaeagnus angustifolia and Hippophae rhamnoides was observed by decreasing fine roots less than 2 mm in diameter, increasing medium roots 2? mm or more than 5 mm in diameter, and deepening root distribution. Pinus sylvestris var. mongolica was drought tolerant by decreasing the growth of aboveground parts and root system; while Moms alba trees exhibited poor adaptability to sandy land.%通过地上生长量、根系垂直分布和形态特征分析以及系统聚类分析,对11个树种在北京大兴沙地生长的适宜性进行了研究.结果表明:各树种的树高、直径、新梢生长量和相对生长以及根系长度、根系表面积、根系体积和比根长等指标均有极显著的差异(p<0.001).其中,臭椿(Ailanthus altissima)、楸树(Catalpa bungei)细根分化极强,皂角(Gleditsia sinensis)、圆柏(Sabina chinensis和栾树(Koelreuteria paniculata)根系分化能力较强,通过较高的土壤资源消耗体现抗旱能力;酸枣(Ziziphus jujuba)、沙枣(Elaeagnus angustifolia)和沙棘(Hippophae rhamnoides)通过降低直径小于2 mm根系分化、提高直径2~5mm和大于5 mm根系生长和分布深度体现

  12. Prevalence of behavioral and emotional problems among seven to eleven year old children in selected schools in Kandy District, Sri Lanka.

    Science.gov (United States)

    Ginige, P; Tennakoon, S U B; Wijesinghe, W H M K J; Liyanage, L; Herath, P S D; Bandara, K

    2014-01-01

    Behavioral and emotional problems comprising internalizing, externalizing and mixed disorders consist of psychiatric disorders in childhood and adolescents. Prevalence rates of 8.3% for preschoolers, 12.2% for preadolescents and 15.0% for adolescents have been reported from around the world. This study aimed to measure the prevalence of emotional and behavioral disorders in 7-11 year-old school children studying in Kandy District Sri Lanka which was a first for the geographic area. This was a community based study at the primary section of the selected schools. The questionnaire, Child behavior Checklist-Sinhala (CBCL-S) was administered in a group setting to the main caregiver of 562 subjects selected randomly. The questionnaire identified problems in 8 subscales under three main sub categories : internalizing, externalizing and other. Data were analyzed using The Syndrome Scales for Boys and Girls developed for analyzing the questionnaire CBCL. Indicated a prevalence of 13.8% of emotional and behavioral problems in the study population. 8.8% of children showed internalizing problems and 8.8% externalizing problems. These findings are in line with the prevailing rates from previous studies of the world. Children in school types 1AB and 1C had less emotional and behavioral problems compared to type 2 and 3 schools. Only 20 schools in KEZ and Sinhala speaking population of the Kandy were studied. This study showed the extent of childhood emotional and behavioral problems and also confirms that the schools with advanced level classes have lesser problems amongst primary children. Copyright © 2014 Elsevier B.V. All rights reserved.

  13. The Dose of Exposure and Prevalence Rates of Post Traumatic Stress Disorder in a Sample of Turkish Children Eleven Months After the 1999 Marmara Earthquakes

    Science.gov (United States)

    Bulut, Sefa; Bulut, Solmaz; Tayli, Asli

    2005-01-01

    Since Turkey is a centrally prime earthquake zone, Turkey's children are at risk for developing Post Traumatic Stress Disorder (PTSD) caused by earthquake exposures and threats of anticipated earthquakes. Given the gaps in the literature and the risk to children living in Turkey, the present study was undertaken to investigate the severity and…

  14. A survey of sesamin and composition of tocopherol variability from seeds of eleven diverse sesame (Sesamum indicum L.) genotypes using HPLC-PAD-ECD.

    Science.gov (United States)

    Williamson, Kelly S; Morris, J Brad; Pye, Quentin N; Kamat, Chandrashekhar D; Hensley, Kenneth

    2008-01-01

    The objective of this study was to determine the composition and content of sesamin and desmethyl tocopherols such as alpha-tocopherol (alphaT), delta-tocopherol (deltaT) and gamma-tocopherol (gammaT) in seeds of sesame (Sesamum indicum L.) for 11 genotypes conserved in the United States Department of Agriculture (USDA), Agricultural Research Service (ARS) and Plant Genetic Resources Conservation Unit (PGRCU) in Griffin, Georgia, USA. Seed accessions studied were collections from eight countries worldwide, including one landrace from Thailand and two cultivars from Texas, USA. Novel methodologies and analytical techniques described herein consisted of reverse-phase high-performance liquid chromatography (HPLC) connected in series with two detection systems specific for each analyte class. Photodiode array detection was employed for sesamin analysis and electrochemical array detection was used in the determination of tocopherols. A preliminary study was conducted to assess sesamin levels in 2003 and tocopherol levels in 2004 from sesame seed samples conserved at the USDA, ARS and PGRCU. In 2005, sesame seed samples were grown, harvested and evaluated for sesamin as well as tocopherol levels. The overall results (n = 3) showed that sesamin, alphaT, deltaT and gammaT levels were 0.67-6.35 mg/g, 0.034-0.175 microg/g, 0.44-3.05 microg/g and 56.9-99.3 microg/g respectively, indicating that the sesame seed accessions contained higher levels of sesamin and gammaT compared with alphaT and deltaT. Statistical analysis was conducted and significant differences were observed among the 11 different sesame genotypes. This suggests that genetic, environmental and geographical factors influence sesamin and desmethyl tocopherol content.

  15. The standardized ileal digestible isoleucine-to-lysine requirement ratio may be less than fifty percent in eleven- to twenty-three-kilogram piglets.

    Science.gov (United States)

    Barea, R; Brossard, L; Le Floc'h, N; Primot, Y; van Milgen, J

    2009-12-01

    Most studies concerning the Ile requirement in pigs have been carried out using blood products as a protein source, and these have a relatively low Ile content relative to the other branched-chain AA (BCAA). There are indications that an excess supply of one BCAA can affect the utilization of the other BCAA. Little information is available concerning the Ile requirement in pigs when the supply of the other BCAA is moderate (e.g., in cereal- and soybean meal-based diets). The objective of the present study was to evaluate the response of piglets to Ile supplementation under different nutritional conditions. In all experiments, piglets were housed individually and had ad libitum access to feed during a 3-wk period. The first experiment was carried out to study the response of piglets to an increasing Ile supply by using 2 sources of l-Ile differing in degree of purity. Piglets received either a control diet with 48% standardized ileal digestible (SID) Ile:Lys or 1 of 4 other diets containing graded levels of either source of l-Ile to provide 52 or 56% SID Ile:Lys. All diets were formulated to provide 1.00% SID Lys in the diet. Feed intake and growth were not affected by Ile level or Ile source. Experiment 2 was performed to exclude a possible interaction between Ile and Lys supply. In a 2 x 2 factorial arrangement, 2 levels of Lys (1.00 and 1.15% SID Lys) and 2 levels of Ile (48 and 60% SID Ile:Lys) were used. Growth and G:F were 8 and 7% greater in piglets receiving the diet with the greater Lys content, but the Ile:Lys did not affect performance. No interactions were observed between the Lys and Ile supplies. In Exp. 3, a 2 x 2 factorial arrangement was used to test the effect of protein source (spray-dried blood cells or corn gluten meal) and Ile supply (50 or 65% SID Ile:Lys) on performance in piglets. Both protein sources had an elevated BCAA content but differed in Leu and Val contents. Protein source or Ile supply did not affect feed intake, growth, or G:F in

  16. Chromatographic background drift correction coupled with parallel factor analysis to resolve coelution problems in three-dimensional chromatographic data: quantification of eleven antibiotics in tap water samples by high-performance liquid chromatography coupled with a diode array detector.

    Science.gov (United States)

    Yu, Yong-Jie; Wu, Hai-Long; Fu, Hai-Yan; Zhao, Juan; Li, Yuan-Na; Li, Shu-Fang; Kang, Chao; Yu, Ru-Qin

    2013-08-01

    Chromatographic background drift correction has been an important field of research in chromatographic analysis. In the present work, orthogonal spectral space projection for background drift correction of three-dimensional chromatographic data was described in detail and combined with parallel factor analysis (PARAFAC) to resolve overlapped chromatographic peaks and obtain the second-order advantage. This strategy was verified by simulated chromatographic data and afforded significant improvement in quantitative results. Finally, this strategy was successfully utilized to quantify eleven antibiotics in tap water samples. Compared with the traditional methodology of introducing excessive factors for the PARAFAC model to eliminate the effect of background drift, clear improvement in the quantitative performance of PARAFAC was observed after background drift correction by orthogonal spectral space projection.

  17. Organizing energy conservation with energy service companies (ESCo's). White paper 2. The vision of experts and eleven examples; Energiebesparing organiseren met ESCo's. White paper 2. De visie van experts en elf praktijkvoorbeelden

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-06-15

    In the first five articles experts describe the position and opportunities of Energy Service Companies (ESCO's) in the Netherlands. Their insights can help to shape an own vision and discover practical opportunities. In the second part eleven examples are given which offer a wide variety of building types and diverse variants of ESCo's [Dutch] In de eerste vijf artikelen beschrijven deskundigen de positionering en kansen van Energy Service Companies (ESCo's) in Nederland. Hun inzichten kunnen helpen om een eigen visie en praktische mogelijkheden vorm te geven. In het tweede deel worden elf praktijkvoorbeelden gegeven die een breed overicht bieden met verschillende gebouwsoorten en uiteenlopende ESCo-varianten.

  18. An Introduction to the E-ELT Instrumentation and Post-focal Adaptive Optics Module Studies

    Science.gov (United States)

    D'Odorico, S.; Ramsay, S.; Hubin, N.; Gonzalez, J. C.; Zerbi, F. M.

    2010-06-01

    The following eleven articles provide short summaries of the conceptual design studies for the European Extremely Large Telescope instruments and post-focal adaptive optics modules. The background and scope of these studies is outlined in this introduction.

  19. Essential Oils Extracted Using Microwave-Assisted Hydrodistillation from Aerial Parts of Eleven Artemisia Species: Chemical Compositions and Diversities in Different Geographical Regions of Iran

    Directory of Open Access Journals (Sweden)

    Majid Mohammadhosseini

    2017-03-01

    Full Text Available This study aimed to assess the chemical compositions of essential oils (EOs extracted through microwave-assisted hydrodistillation from aerial parts of 11 Artemisia species growing wild in different regions in Northern, Eastern, Western, and Central parts of Iran. The EOs were subsequently analyzed via GC and GC-MS. The percentage yields of the EOs varied over the range of 0.21-0.50 (w/w%. On the basis of these characterizations and spectral assignments, natural compounds including camphor, 1,8-cineole, camphene, α-pinene, β-pinene, β-thujone, and sabinene were the most abundant and frequent constituents among all studied chemical profiles. Accordingly, oxygenated monoterpenes, monoterpene hydrocarbons, and non-terpene hydrocarbons were the dominant groups of natural compounds in the chemical profiles of 13, 4, and 2 samples, respectively. Moreover, five chemotypes were identified using statistical analyses: camphene, α-pinene and β-pinene; 1,8-cineole; camphore and 1,8-cineole; camphore and camphore and β-thujone.

  20. Chest trauma experience over eleven-year period at al-mouassat university teaching hospital-Damascus: a retrospective review of 888 cases.

    Science.gov (United States)

    Al-Koudmani, Ibrahim; Darwish, Bassam; Al-Kateb, Kamal; Taifour, Yahia

    2012-04-19

    Thoracic trauma is one of the leading causes of morbidity and mortality in developing countries. In this study, we present our 11-year experience in the management and clinical outcome of 888 chest trauma cases as a result of blunt and penetrating injuries in our university hospital in Damascus, Syria. We reviewed files of 888 consequent cases of chest trauma between January 2000 and January 2011. The mean age of our patients was 31 ± 17 years mostly males with blunt injuries. Patients were evaluated and compared according to age, gender, etiology of trauma, thoracic and extra-thoracic injuries, complications, and mortality. The leading cause of the trauma was violence (41%) followed by traffic accidents (33%). Pneumothorax (51%), Hemothorax (38%), rib fractures (34%), and lung contusion (15%) were the most common types of injury. Associated injuries were documented in 36% of patients (extremities 19%, abdomen 13%, head 8%). A minority of the patients required thoracotomy (5.7%), and tube thoracostomy (56%) was sufficient to manage the majority of cases. Mean hospital LOS was 4.5 ± 4.6 days. The overall mortoality rate was 1.8%, and morbidity (n = 78, 8.7%). New traffic laws (including seat belt enforcement) reduced incidence and severity of chest trauma in Syria. Violence was the most common cause of chest trauma rather than road traffic accidents in this series, this necessitates epidemiologic or multi-institutional studies to know to which degree violence contributes to chest trauma in Syria. The number of fractured ribs can be used as simple indicator of the severity of trauma. And we believe that significant neurotrauma, traffic accidents, hemodynamic status and GCS upon arrival, ICU admission, ventilator use, and complication of therapy are predictors of dismal prognosis.

  1. Chest trauma experience over eleven-year period at al-mouassat university teaching hospital-Damascus: a retrospective review of 888 cases

    Directory of Open Access Journals (Sweden)

    Al-Koudmani Ibrahim

    2012-04-01

    Full Text Available Abstract Background Thoracic trauma is one of the leading causes of morbidity and mortality in developing countries. In this study, we present our 11-year experience in the management and clinical outcome of 888 chest trauma cases as a result of blunt and penetrating injuries in our university hospital in Damascus, Syria. Methods We reviewed files of 888 consequent cases of chest trauma between January 2000 and January 2011. The mean age of our patients was 31 ± 17 years mostly males with blunt injuries. Patients were evaluated and compared according to age, gender, etiology of trauma, thoracic and extra-thoracic injuries, complications, and mortality. Results The leading cause of the trauma was violence (41% followed by traffic accidents (33%. Pneumothorax (51%, Hemothorax (38%, rib fractures (34%, and lung contusion (15% were the most common types of injury. Associated injuries were documented in 36% of patients (extremities 19%, abdomen 13%, head 8%. A minority of the patients required thoracotomy (5.7%, and tube thoracostomy (56% was sufficient to manage the majority of cases. Mean hospital LOS was 4.5 ± 4.6 days. The overall mortoality rate was 1.8%, and morbidity (n = 78, 8.7%. Conclusions New traffic laws (including seat belt enforcement reduced incidence and severity of chest trauma in Syria. Violence was the most common cause of chest trauma rather than road traffic accidents in this series, this necessitates epidemiologic or multi-institutional studies to know to which degree violence contributes to chest trauma in Syria. The number of fractured ribs can be used as simple indicator of the severity of trauma. And we believe that significant neurotrauma, traffic accidents, hemodynamic status and GCS upon arrival, ICU admission, ventilator use, and complication of therapy are predictors of dismal prognosis.

  2. The effects of twelve weeks of bed rest on bone histology, biochemical markers of bone turnover, and calcium homeostasis in eleven normal subjects

    Science.gov (United States)

    Zerwekh, J. E.; Ruml, L. A.; Gottschalk, F.; Pak, C. Y.; Blomqvist, C. G. (Principal Investigator)

    1998-01-01

    This study was undertaken to examine the effects of 12 weeks of skeletal unloading on parameters of calcium homeostasis, calcitropic hormones, bone histology, and biochemical markers of bone turnover in 11 normal subjects (9 men, 2 women; 34 +/- 11 years of age). Following an ambulatory control evaluation, all subjects underwent 12 weeks of bed rest. An additional metabolic evaluation was performed after 12 days of reambulation. Bone mineral density declined at the spine (-2.9%, p = 0.092) and at the hip (-3.8%, p = 0.002 for the trochanter). Bed rest prompted a rapid, sustained, significant increase in urinary calcium and phosphorus as well as a significant increase in serum calcium. Urinary calcium increased from a pre-bed rest value of 5.3 mmol/day to values as high as 73 mmol/day during bed rest. Immunoreactive parathyroid hormone and serum 1,25-dihydroxyvitamin D declined significantly during bed rest, although the mean values remained within normal limits. Significant changes in bone histology included a suppression of osteoblastic surface for cancellous bone (3.1 +/- 1.3% to 1.9 +/- 1.5%, p = 0.0142) and increased bone resorption for both cancellous and cortical bone. Cortical eroded surface increased from 3.5 +/- 1.1% to 7.3 +/- 4.0% (p = 0.018) as did active osteoclastic surface (0.2 +/- 0.3% to 0.7 +/- 0.7%, p = 0.021). Cancellous eroded surface increased from 2.1 +/- 1.1% to 4.7 +/- 2.2% (p = 0.002), while mean active osteoclastic surface doubled (0.2 +/- 0.2% to 0.4 +/- 0.3%, p = 0.020). Serum biochemical markers of bone formation (osteocalcin, bone-specific alkaline phosphatase, and type I procollagen extension peptide) did not change significantly during bed rest. Urinary biochemical markers of bone resorption (hydroxyproline, deoxypyridinoline, and N-telopeptide of type I collagen) as well as a serum marker of bone resorption (type I collagen carboxytelopeptide) all demonstrated significant increases during bed rest which declined toward normal

  3. The Association between Parent Diet Quality and Child Dietary Patterns in Nine- to Eleven-Year-Old Children from Dunedin, New Zealand

    Directory of Open Access Journals (Sweden)

    Brittany Davison

    2017-05-01

    Full Text Available Previous research investigating the relationship between parents’ and children’s diets has focused on single foods or nutrients, and not on global diet, which may be more important for good health. The aim of the study was to investigate the relationship between parental diet quality and child dietary patterns. A cross-sectional survey was conducted in 17 primary schools in Dunedin, New Zealand. Information on food consumption and related factors in children and their primary caregiver/parent were collected. Principal component analysis (PCA was used to investigate dietary patterns in children and diet quality index (DQI scores were calculated in parents. Relationships between parental DQI and child dietary patterns were examined in 401 child-parent pairs using mixed regression models. PCA generated two patterns; ‘Fruit and Vegetables’ and ‘Snacks’. A one unit higher parental DQI score was associated with a 0.03SD (CI: 0.02, 0.04 lower child ‘Snacks’ score. There was no significant relationship between ‘Fruit and Vegetables’ score and parental diet quality. Higher parental diet quality was associated with a lower dietary pattern score in children that was characterised by a lower consumption frequency of confectionery, chocolate, cakes, biscuits and savoury snacks. These results highlight the importance of parental modelling, in terms of their dietary choices, on the diet of children.

  4. Polymorphisms in twelve candidate genes are associated with growth, muscle lipid profile and meat quality traits in eleven European cattle breeds.

    Science.gov (United States)

    Sevane, N; Armstrong, E; Wiener, P; Pong Wong, R; Dunner, S

    2014-07-01

    Current customers' demands focus on the nutritional and sensory quality of cattle meat. Candidate gene approach allows identification of genetic polymorphisms that have a measurable effect on traits of interest. The aim of this work is to identify new molecular markers for beef production through an association study using 27 candidate genes and 314 purebred bulls from 11 European cattle breeds. Twelve genes were found associated with different lipid and meat quality traits, and among these stand out the considerable effect of CAST on fatness score, CGGBP1 on growth traits, HSPB1 on the percentage of lauric acid (12:0) and phospholipid docosahexaenoic acid (DHA 22:6 n - 3), RORA on the ratio of light absorption (K) to light scattering (S) (K/S), and TNFA on lightness (L*). Most of these traits are related to post-mortem muscle biochemical changes, which are key factors controlling meat quality and consumers' acceptance. Also, the variations produced on muscle fatty acid profiles, such as those of AANAT, CRH, CSN3, HSPB1, and TNFA, give insights into the genetic networks controlling these complex traits and the possibility of future improvement of meat nutritional quality.

  5. Eleven Years of Data on the Jefferson Scale of Empathy-Medical Student Version (JSE-S): Proxy Norm Data and Tentative Cutoff Scores.

    Science.gov (United States)

    Hojat, Mohammadreza; Gonnella, Joseph S

    2015-01-01

    This study was designed to provide typical descriptive statistics, score distributions and percentile ranks of the Jefferson Scale of Empathy-Medical Student version (JSE-S) of male and female medical school matriculants to serve as proxy norm data and tentative cutoff scores. The participants were 2,637 students (1,336 women and 1,301 men) who matriculated at Sidney Kimmel (formerly Jefferson) Medical College between 2002 and 2012, and completed the JSE at the beginning of medical school. Information extracted from descriptive statistics, score distributions and percentile ranks for male and female matriculants were used to develop proxy norm data and tentative cutoff scores. The score distributions of the JSE tended to be moderately skewed and platykurtic. Women obtained a significantly higher mean score (116.2 ± 9.7) than men (112.3 ± 10.8) on the JSE-S (t2,635 = 9.9, p < 0.01). It was suggested that percentile ranks can be used as proxy norm data. The tentative cutoff score to identify low scorers was ≤ 95 for men and ≤ 100 for women. Our findings provide norm data and cutoff scores for admission decisions under certain conditions and for identifying students in need of enhancing their empathy. © 2015 S. Karger AG, Basel.

  6. MRI-imaging and clinical findings of eleven children with tick-borne encephalitis and review of the literature.

    Science.gov (United States)

    von Stülpnagel, C; Winkler, P; Koch, J; Zeches-Kansy, C; Schöttler-Glas, A; Wolf, G; Niller, H H; Staudt, M; Kluger, G; Rostasy, K

    2016-01-01

    The incidence of tick-borne encephalitis (TBE) is increasing in many countries. Magnetic resonance imaging (MRI) in the course of TBE is not regularly performed in children. The aim of our study was evaluating MRI-findings of children and adolescents with TBE. Retrospective evaluation of the charts and MRIs of patients who had been treated for TBE in the four participating hospitals in the last twenty years. 11 patients (5 male; age at TBE 3 weeks-15 9/12 years; mean 104.9 months) were included. MRI (within the first week after admission) revealed symmetric or asymmetric T2-hyperintensities in both thalami in 7/11 patients with additional bilateral lesions in putamen and/or caudate nucleus in 3 patients, and additional cortical lesions in 2 patients. Our youngest patient presented with T2-hyperintensities affecting the whole left cerebral hemisphere including white and grey matter and both cerebellar hemispheres. One patient had a minimal reversible T2-hyperintensity in the splenium of the corpus callosum (RHSCC). 3/11 patients had a normal MRI. 4/11 patients showed complete neurological recovery (2/4 with a normal MRI, RHSCC patient). 6/11 children survived with significant sequelae: hemiparesis (n = 4); cognitive deficits (n = 4); pharmacoresistant epilepsy (n = 2). One patient died of a malignant brain edema. A spectrum of MRI findings can be found in children with TBE, often showing involvement of the subcortical deep grey matter structures. In children presenting with a meningoencephalitis and bilateral thalamic involvement TBE should be included in the differential diagnosis. Copyright © 2015 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.

  7. Safety and immunogenicity of three doses of an eleven-valent diphtheria toxoid and tetanus protein – conjugated pneumococcal vaccine in Filipino infants

    Directory of Open Access Journals (Sweden)

    Käyhty Helena

    2003-08-01

    Full Text Available Abstract Background An 11-valent pneumococcal conjugate vaccine could provide significantly larger reduction in pneumococcal disease burden than the currently available 7-valent vaccine formulation in many countries. Methods In total, 50 infants were enrolled to this open, uncontrolled study, which evaluated the safety and immunogenicity of an aluminium adjuvanted 11-valent mixed-carrier diphtheria toxoid or tetanus protein-conjugated vaccine (11-PncTD when administered in three doses at 6, 10 and 14 weeks of age simultaneously with DTwP//PRP-T and OPV vaccines in Filipino infants. Results The rates of local reactions between the two injection sites, those associated with the 11-PncTD vaccine and those with the DTwP//PRP-T were almost of equal frequency for all three vaccine doses except for induration, which was significantly more common in the DTP//PRP-T injection site. Fever was present in 39%, 22% and 21% of infants following each of the three doses. Antibody responses were determined by an enzyme immunoassay method before the first vaccination and after the three doses. The vaccine elicited a significant anti-pneumococcal polysaccharide antibody response against all serotypes included in the vaccine, except for type 14, for which the pre-vaccination geometric mean antibody concentration (GMC was high (1.61 μg/ml. The GMCs one month after the vaccination series ranged from 1.1 micrograms/ml for type 6B to 23.4 μg/ml for type 4. Conclusion The 11-PncTD vaccine is safe, well-tolerated and immunogenic. The effectiveness of the non-adjuvanted formulation of the vaccine in preventing pneumonia is currently being evaluated in the Philippines.

  8. Lateral shelf acetabuloplasty for severe Legg-Calvé-Perthes disease in patients older than 8 years: A mean eleven-year follow-up.

    Science.gov (United States)

    Li, Wen-Chao; Xu, Rui-Jiang

    2016-11-01

    The natural history of Legg-Calvé-Perthes disease (LCPD) in children older than 8 years is usually poor without treatment. The treatment goal is to prevent deformity and incongruity of the hip by achieving a stable spherical femoral head in a deep, congruent, sharp-edged acetabulum, with a good range of hip movement at skeletal maturity. Lateral shelf acetabuloplasty in LCPD can increase the coverage of the femoral head, benefiting the remodeling of the femoral head and acetabulum. The aim of this study was to evaluate the efficacy of lateral shelf acetabuloplasty for severe LCPD in patients older than 8 years.We evaluated 51 patients with severe LCPD who underwent shelf acetabuloplasty between 1994 and 2005. Clinical and radiological examinations were evaluated preoperatively and over a mean follow-up of 132.35 months (range 102-183 months). According to the Catterall classification, the LCPD was classified as grade II in 11 (21.6%) patients, grade III in 15 (29.4%), and grade IV in 25 (49.0%). According to the Herring classification, there were 12 (23.5%) patients in grade B, 24 (47.1%) in grade B/C, and 15 (29.4%) in grade C. The mean ages at the onset of signs and at surgery were 103.39 months and 110.78 months, respectively.By the end of follow-up, all patients had a normal passive range of hip movement without pain. The mean Iowa hip score was improved from 69.5 ± 7.28 to 91.6 ± 5.14 (P shelf acetabuloplasty (P shelf acetabuloplasty for severe LCPD in patients older than 8 years. The procedure yields a favorable clinical outcome and Stulberg outcome for the hip. Shelf acetabuloplasty can improve femoral head coverage and reduce subluxation of the hip, with a benefit to the biological remodeling of the femoral head within the acetabulum.

  9. A multi-centre evaluation of eleven clinically feasible brain PET/MRI attenuation correction techniques using a large cohort of patients.

    Science.gov (United States)

    Ladefoged, Claes N; Law, Ian; Anazodo, Udunna; St Lawrence, Keith; Izquierdo-Garcia, David; Catana, Ciprian; Burgos, Ninon; Cardoso, M Jorge; Ourselin, Sebastien; Hutton, Brian; Mérida, Inés; Costes, Nicolas; Hammers, Alexander; Benoit, Didier; Holm, Søren; Juttukonda, Meher; An, Hongyu; Cabello, Jorge; Lukas, Mathias; Nekolla, Stephan; Ziegler, Sibylle; Fenchel, Matthias; Jakoby, Bjoern; Casey, Michael E; Benzinger, Tammie; Højgaard, Liselotte; Hansen, Adam E; Andersen, Flemming L

    2017-02-15

    To accurately quantify the radioactivity concentration measured by PET, emission data need to be corrected for photon attenuation; however, the MRI signal cannot easily be converted into attenuation values, making attenuation correction (AC) in PET/MRI challenging. In order to further improve the current vendor-implemented MR-AC methods for absolute quantification, a number of prototype methods have been proposed in the literature. These can be categorized into three types: template/atlas-based, segmentation-based, and reconstruction-based. These proposed methods in general demonstrated improvements compared to vendor-implemented AC, and many studies report deviations in PET uptake after AC of only a few percent from a gold standard CT-AC. Using a unified quantitative evaluation with identical metrics, subject cohort, and common CT-based reference, the aims of this study were to evaluate a selection of novel methods proposed in the literature, and identify the ones suitable for clinical use. In total, 11 AC methods were evaluated: two vendor-implemented (MR-ACDIXON and MR-ACUTE), five based on template/atlas information (MR-ACSEGBONE (Koesters et al., 2016), MR-ACONTARIO (Anazodo et al., 2014), MR-ACBOSTON (Izquierdo-Garcia et al., 2014), MR-ACUCL (Burgos et al., 2014), and MR-ACMAXPROB (Merida et al., 2015)), one based on simultaneous reconstruction of attenuation and emission (MR-ACMLAA (Benoit et al., 2015)), and three based on image-segmentation (MR-ACMUNICH (Cabello et al., 2015), MR-ACCAR-RiDR (Juttukonda et al., 2015), and MR-ACRESOLUTE (Ladefoged et al., 2015)). We selected 359 subjects who were scanned using one of the following radiotracers: [(18)F]FDG (210), [(11)C]PiB (51), and [(18)F]florbetapir (98). The comparison to AC with a gold standard CT was performed both globally and regionally, with a special focus on robustness and outlier analysis. The average performance in PET tracer uptake was within ±5% of CT for all of the proposed methods, with the

  10. GABLS3-LES Intercomparison Study

    NARCIS (Netherlands)

    Basu, S.; Holtslag, A.A.M.; Bosveld, F.C.

    2012-01-01

    Recently, a large-eddy simulation (LES) intercomparison study was organized under the auspices of the GEWEX Atmospheric Boundary Layer Study (GABLS). Eleven LES modelling groups around the world participated in this study to model a baroclinic, mid-latitude nighttime stable boundary layer utilizing

  11. Eleven-year Experience with Radial Keratotomy

    Institute of Scientific and Technical Information of China (English)

    Akira; Momose

    1994-01-01

    1 900 consecutive eyes that underwent radial keratotomy by the senior author were evaluated retrospectively. 3 months after surgery, minimum reduction in mean spherical equivalent of 0. 67D was achieved with 1 incision and maximum 7. 250 with 24 incisions. Unconnected visual acuity of 20/40 or better was obtained in 99. 4% of eyes with low myopia, 64. 2% with moderate myopia and 32. 4% with high myopia. For anisometropia, bilateral RK reduced refractive error from -12. 12D to -5. 22D in more myopic eyes...

  12. Radial Keratotomy:Eleven-year Experiences

    Institute of Scientific and Technical Information of China (English)

    1992-01-01

    During the period from 1980 to 1991,Radial Keratotomy(RK)hadbeen done by the author under topical anesthesia in more than 10000 cases,mostly on both eyes at the same time.Those patients had myopia with apreoperative refractive error between 1.5 and 20.0 diopters(D).The surgicaltechnique consisted of 4,8,16 incisions using a diamond knife with micrometerand the diameter of the central clear zone was mostly 3.0mm and determinedby preoperative refractive error.Many different procedures were tried to im-pro...

  13. 2010 ARRA Lidar: Eleven County Virginia

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Terrapoint and LMSI collected LiDAR for over 2,572 square miles in Northumberland, Lancaster, Middlesex, King and Queen, Matthews, Gloucester, James City,...

  14. EPEC-O Self-Study - Module 11 - Withdrawing Nutrition, Hydration

    Science.gov (United States)

    Module eleven of the EPEC-O Self-Study Original Version discusses the general aspects of withholding or withdrawing of life-sustaining therapies, and presents a specific application to artificial nutrition and hydration.

  15. 催化裂化回炼油加氢精制反应十一集总宏观动力学模型%The Eleven Lumped Macrokinetics Model for Hydrotreating Reactions of FCC Recycle Oil

    Institute of Scientific and Technical Information of China (English)

    张奎; 戴立顺; 刘涛; 聂红

    2012-01-01

    针对催化裂化回炼油加氢精制反应特点,运用集总方法对催化裂化回炼油及其加氢精制油中烃类组成进行十一集总划分,并通过MatLab软件对各集总加氢精制反应动力学方程进行模拟计算,建立了催化裂化回炼油加氢精制反应十一集总宏观动力学模型.所建模型可体现不同烃类间加氢反应性能的差异;加氢反应网络可反映催化裂化回炼油的加氢精制反应过程;在计算过程中设定各集总质量分数反应级数为一级,求出其他动力学参数数值.验证实验表明,该模型可较好地预测催化裂化回炼油在一定加氢条件下的烃类组成分布.%Eleven lumps for the hydrocarbons of FCC recycle oil and hydrotreated FCC recycle oil were divided through the lumped method to investigate the hydrotreating reaction feature, then the eleven lumped macrokinetics model for the hydrotreating reactions of FCC recycle oil was established through the analog computation of the kinetic equations of hydrotreating reactions with the MatLab software. This model could display the difference in performance of hydrogenation reactions among hydrocarbons. Meanwhile the hydrogenation reaction network could reflect the hydrotreating reaction process of FCC recycle oil. The reaction order for lumps was set as one in the process of computation, and other kinetic parameters were obtained. It was found through verification test that this model could predict the hydrocarbon component distribution of FCC recycle oil under certain hydrotreating conditions.

  16. The Effects of the Federal Work-Study Program on Student Persistence and Accrued Loan Debt

    Science.gov (United States)

    Carter, Ronatta Daphne

    2012-01-01

    This study examined the impact of participation and non-participation in a federal work-study (FWS) program on student persistence and accrued student debt for undergraduate students enrolled in a small, public, four-year, liberal arts college in the South. Sanford's (1967) theory of Challenge and Support and Tinto's (1986) Integration Model were…

  17. 气相色谱内标法测定食品中多种常见防腐剂的含量%Determination of eleven preservatives in food by gas chromatography

    Institute of Scientific and Technical Information of China (English)

    顾秀英; 欧菊芳; 王东铭; 鲍忠定; 许荣年

    2012-01-01

    采用乙醚提取,进%GC—FID,采用内标(十一烷酸)法对食品中11种防腐剂进行定量测定,该方法线性良好,检出限为0.84~5.01mg/kg,精密度为2.0%~3.6%,回收率在90.6%-98.8%,此方法操作简便,抗基质干扰、结果可靠,适合食品中多种防腐剂含量的准确测定。%A method was developed for determination of eleven preservatives in food sample by GC-FID, and preservatives were extracted by diethyl ether and were quantified by internal standard (undecanoic acid) method, the regression coefficient for the determination of the method is good, the detection limit and the accuracy for the determination of the method were 0.84-5.01 mg/kg and 2.0%-3.6%. The recoveris were 90.6%-98.8%. It showed that the method was simple and easy to handle, obstruction of bases decreased obviously, It's suit for the determination of preservatives in food.

  18. MicroRNA-494 is a master epigenetic regulator of multiple invasion-suppressor microRNAs by targeting ten eleven translocation 1 in invasive human hepatocellular carcinoma tumors

    Science.gov (United States)

    Chuang, Kuang-Hsiang; Whitney-Miller, Christa L; Chu, Chin-Yi; Zhou, Zhongren; Dokus, M Katherine; Schmit, Shannon; Barry, Christopher T

    2015-01-01

    Vascular invasion provides a direct route for tumor metastasis. The degree to which microRNA (miRNA) expression plays a role in tumor vascular invasion is unclear. Here, we report that miR-494 is up-regulated in human hepatocellular carcinoma (HCC) tumors with vascular invasion and can promote HCC cell invasiveness by gene inactivation of multiple invasion-suppressor miRNAs. Our results show that ten eleven translocation (TET) methylcytosine dioxygenase, predominantly TET1 in HCC cells, is a direct target of miR-494. The reduced 5′-hydroxymethylcytosine levels observed in the proximal cytosine-phosphate-guanine (CpG) regions of multiple invasion-suppressor miRNA genes are strongly associated with their transcriptional repression upon miR-494 overexpression, whereas enforced DNA demethylation can abolish the repression. Furthermore, TET1 knockdown shows a similar effect as miR-494 overexpression. Conversely, miR-494 inhibition or enforced TET1 expression is able to restore invasion-suppressor miRNAs and inhibit miR-494-mediated HCC cell invasion. Conclusions: miR-494 can trigger gene silencing of multiple invasion-suppressor miRNAs by inhibiting genomic DNA demethylation by direct targeting of TET1, thereby leading to tumor vascular invasion. (Hepatology 2015;62:466–480 PMID:25820676

  19. An Analysis of Asynchronous Discussions: A Case Study of Graduate Student Participation in Online Debates

    Science.gov (United States)

    Davidson-Shivers, Gayle V.; Luyegu, Eunice; Kimble, Barbara E.

    2012-01-01

    Non-participation and poor quality participation in online environments is often discussed in the literature. Interaction and engagement in online discussions are critical for understanding and constructing new knowledge. In this case study, we examined messages posted by graduate students in four online debates for quantity and quality. The…

  20. A Study of the Effectiveness of Learning Communities at a Small Liberal Arts College

    Science.gov (United States)

    Watkins, Paul David

    2013-01-01

    The purpose of this study is to determine the effectiveness of the learning community program at a small liberal arts college on educational outcomes as measured by differences in semester GPA between learning community participants and non-participants, as well as differences between types of learning communities, time of participation in…

  1. Mindfulness training for medical students in their clinical clerkships: two cross-sectional studies exploring interest and participation

    NARCIS (Netherlands)

    Dijk, I. van; Lucassen, P.L.B.J.; Speckens, A.E.M.

    2015-01-01

    BACKGROUND: So far, studies investigating Mindfulness Based Stress Reduction (MBSR) training in medical students are conducted in self-selected, pre-clinical samples, with modest response rates without collecting data on non-participants. This study first examines interest and participation rates of

  2. Improved results in paediatric diabetes care using a quality registry in an improvement collaborative: a case study in Sweden.

    Directory of Open Access Journals (Sweden)

    Anette Peterson

    Full Text Available Several studies show that good metabolic control is important for children and adolescents with type 1 diabetes. In Sweden, there are large differences in mean haemoglobin A1c (HbA1c in different hospitals and difficulties implementing national guidelines in everyday practice. This study shows how the participation in an improvement collaborative could facilitate improvements in the quality of care by paediatric diabetes teams. The Swedish paediatric diabetes quality registry, SWEDIABKIDS was used as a tool and resource for feedback and outcome measures.Twelve teams at paediatric diabetes centres, caring for 30% (2302/7660 of patients in Sweden, participated in an 18-month quality improvement program. Each team defined treatment targets, areas needing improvement, and action plans. The main outcome was the centre patients' mean HbA1c levels, but other clinical variables and change concepts were also studied. Data from the previous six months were compared with the first six months after starting the program, and the long-term follow up after another eleven months.All centres reduced mean HbA1c during the second and third periods compared with the first. The mean reduction for all was 3·7 mmol/mol (p<0.001, compared with non-participating centres who improved their mean HbA1c with 1·7 mmol/mol during the same period. Many of the participating centres reduced the frequency of severe hypoglycaemia and/or ketoacidosis, and five centres reached their goal of ensuring that all patients had some sort of physical activity at least once weekly. Change concepts were, for example, improved guidelines, appointment planning, informing the patients, improving teamwork and active use of the registry, and health promotion activities.By involving paediatric diabetes teams in a quality improvement collaborative together with access to a quality register, the quality of paediatric diabetes care can improve, thereby contributing to a reduced risk of late

  3. Reasons for women's non-participation in follow-up screening after gestational diabetes

    DEFF Research Database (Denmark)

    Nielsen, Jane Hyldgaard; Olesen, Christinna Rebecca; Kristiansen, Tine Mechlenborg;

    2015-01-01

    Background: Due to the increased risk of type 2 diabetes, follow-up screening after birth is recommended to women with previous gestational diabetes. Low participation in such screening has been shown to delay detection of diabetes with potentially serious consequences for the women's future health...

  4. Why concern regarding privacy differs : The influence of age and (non-)participation on Facebook

    NARCIS (Netherlands)

    Steijn, Wouter; Schouten, Alexander Peter; Vedder, Anton

    2016-01-01

    Young people have obtained a reputation for caring less about their privacy due to their self-revealing presence on social media. Although one might easily be inclined to think that young people do not care about their privacy, an explanation for this could be that young people simply have a

  5. Why concern regarding privacy differs : The influence of age and (non-)participation on Facebook

    NARCIS (Netherlands)

    Steijn, Wouter; Schouten, Alexander Peter; Vedder, Anton

    2016-01-01

    Young people have obtained a reputation for caring less about their privacy due to their self-revealing presence on social media. Although one might easily be inclined to think that young people do not care about their privacy, an explanation for this could be that young people simply have a differe

  6. Histopathological and ultrastructural study on face lesions of eleven cases with melasma%11例黄褐斑面部皮损组织病理及超微病理

    Institute of Scientific and Technical Information of China (English)

    乔丽; 赵广; 马慧军

    2007-01-01

    目的:比较黄褐斑患者面部皮损及临近非皮损的组织病理及超微病理学特点.方法:选择11例门诊确诊的黄褐斑患者,对皮损和临近非皮损取活检,分别进行苏木素-伊红、Fontana-Masson染色、HMB45、NKI/beteb免疫组化染色和电镜观察.计算机图像分析技术量化分析.结果:同邻近正常皮损相比,黄褐斑皮损表皮全层色素明显增加,基底层黑素细胞数量无改变.真皮载色素细胞增加.超微结构显示黄褐斑皮损黑素细胞内线粒体、高尔基体、粗质内质网、核糖体及成熟黑素小体数量增加,角质形成细胞内有大量吞噬的Ⅲ期、Ⅳ期黑素小体.结论:黄褐斑皮损的色素增加,可能与多种因素引起的黑素细胞功能活跃和黑素颗粒在表皮内转运增加有关.

  7. The Mechnism Discussion of the Theory of the Eleven Organs Depended by Gallbladder in Huangdi's Canon of Medicine%《内经》“凡十一脏取决于胆”机制探析

    Institute of Scientific and Technical Information of China (English)

    潘毅

    2011-01-01

    The passage thought there were two explanations to the theory of the eleven organs depended by gallbladder in Huangdis Canon of Medicine on the basis of the other views of specialist.Firstly, it agreed with the view of the gallbladder corresponds to the spring and processes the rising and growing QI which put emphasis on the depending Qi based on the theory of the unity of organs and timing in Su Wen six - six system and Visceral manifestation. Secondly, it agreed with the view of the gallbladder, it can be used to judge organ to make decision which put emphasis on the depending of spirit. The speech focused on the relationship of judging and decision - making and depending and made mechanism discussion for the reason of the unclear of explanation of the second view. The spirit and Qi can promote each other, so the two views can supplement to each other too.%在归纳《黄帝内经》颇具争议的“凡十一脏取决于胆”一语的诸家之见基础上,认为有两解可互参互补.其一,基于《素问·六节藏象论》以时节论脏腑的天人背景,同意以胆气应春,具生、升之气为解,此偏“气”之“取决”;其二,胆为中正之官取决论亦具意义,此偏“神”之“取决”.鉴于历来持后见者之释常语焉不详,笔者着重就中正与决断、决断与取决关系作了机制探析,或存启示.“神”与“气”,本就气能生神,神能驭气关系,两种见解,自可并行不悖,互为补充.

  8. Potential health gains and health losses in eleven EU countries attainable through feasible prevalences of the life-style related risk factors alcohol, BMI, and smoking: a quantitative health impact assessment.

    Science.gov (United States)

    Lhachimi, Stefan K; Nusselder, Wilma J; Smit, Henriette A; Baili, Paolo; Bennett, Kathleen; Fernández, Esteve; Kulik, Margarete C; Lobstein, Tim; Pomerleau, Joceline; Boshuizen, Hendriek C; Mackenbach, Johan P

    2016-08-05

    Influencing the life-style risk-factors alcohol, body mass index (BMI), and smoking is an European Union (EU) wide objective of public health policy. The population-level health effects of these risk-factors depend on population specific characteristics and are difficult to quantify without dynamic population health models. For eleven countries-approx. 80 % of the EU-27 population-we used evidence from the publicly available DYNAMO-HIA data-set. For each country the age- and sex-specific risk-factor prevalence and the incidence, prevalence, and excess mortality of nine chronic diseases are utilized; including the corresponding relative risks linking risk-factor exposure causally to disease incidence and all-cause mortality. Applying the DYNAMO-HIA tool, we dynamically project the country-wise potential health gains and losses using feasible, i.e. observed elsewhere, risk-factor prevalence rates as benchmarks. The effects of the "worst practice", "best practice", and the currently observed risk-factor prevalence on population health are quantified and expected changes in life expectancy, morbidity-free life years, disease cases, and cumulative mortality are reported. Applying the best practice smoking prevalence yields the largest gains in life expectancy with 0.4 years for males and 0.3 year for females (approx. 332,950 and 274,200 deaths postponed, respectively) while the worst practice smoking prevalence also leads to the largest losses with 0.7 years for males and 0.9 year for females (approx. 609,400 and 710,550 lives lost, respectively). Comparing morbidity-free life years, the best practice smoking prevalence shows the highest gains for males with 0.4 years (342,800 less disease cases), whereas for females the best practice BMI prevalence yields the largest gains with 0.7 years (1,075,200 less disease cases). Smoking is still the risk-factor with the largest potential health gains. BMI, however, has comparatively large effects on morbidity. Future

  9. Chromosome number and satellited chromosome morphology of eleven species of Arachis (Leguminosae Número cromosómico y morfología del cromosoma satelitado en once espécies de Arachis (Leguminosae

    Directory of Open Access Journals (Sweden)

    Andréa del Pilar De Souza Penaloza

    2010-08-01

    Full Text Available The chromosome number was determined in eleven recently-described species of Arachis belonging to five different taxonomic sections. Two new species of section Arachis, A. Gregor/i and A. Krapovickasii, present 2n=20 chromosomes and lack the small 'A' pair, while A. linearifolia and A. Schininii have 2n=20, including the small 'A' pair of chromosomes, typical of the A genome of A. hypogaea. Arachis Schininii, previously listed under A. Hoehnei, a species lacking this pair of chromosomes, has many morphological differences, and is therefore considered to be a new species. Arachis submarginata (sect. Extranervosae, A. Pflugeae and A. Hassleri (sect. Procumbentes, and A. serdoensis and A. interrupta (sect. Heteranthae also have 2n=20. One species of section Rhizomatosae, A. nitida, is tetraploid (2n=40, but is morphologically distinct from the other tetraploids in this section. The new species of section Erectoides, A. porphyrocalyx, shows 2n=18. This is the first count of 2n=18 chromosomes for an Arachis species outside section Arachis and its origin is probably not associated with the origin of the 18 chromosomes occurring in three species of section Arachis Se determinó el número cromosómico de once especies recientemente descriptas del género Arachis, pertenecientes a cinco secciones taxonómicas. En la sección Arachis, A. Gregoryi y A. Krapovickasii presentan 2n=20 cromosomas sin el par "A", mientras A. linearifolia y A. Schininii presentan 2n=20, incluyendo el par "A", típico del genomio A de A. hypogaea. Arachis Schininii presenta características citológicas (presencia del par "A" y morfológicas distintas de A. Hoehnei, bajo la cual estuvo incluida. Arachis submarginata (sección Extranervosaé, A. Pflugeae y A. Hassleri (sección Procumbentes, y A. seridoensis y A. interrupta (sección Heteranthae también presentan 2n=20. Una especie de la sección Rhizomatosae, A. nitida, es tetraploide, con 2n=40, pero morfológicamente distinta

  10. Detection of Eleven Pathogenic Bacterium Using DNA Microarray Combined With Multiplex PCR%多重PCR结合基因芯片技术检测11种致病菌方法的建立

    Institute of Scientific and Technical Information of China (English)

    贺晨; 孙鸿燕; 邵丽筠; 刘金华; 张春秀; 刘娅

    2011-01-01

    Objective To establish a rapid ,accurate detection method for 11 kinds of pathogenic bacteria using DNA microarray combined with multiplex PCR .Methods The special genes of these Bacterium including Shigella, Listeria monocytogenes ,Escherichi-a coli O157, Staphylococcus aureus , Bacillus cereus , Campylobacter jejuni, Proteusbacillus vulgaris , C . perfringens , Vibiro para-haemolyticus ,Salmonella typhi ,Salmonella enteritidis were as target genes for multiplex PCR respectively ,then primers and captured oligonucleotide probes were designed and synthesized .After multiplex PCR system and hybridization reaction were optimized ,the multr-plex PCR products were hybridizes with DNA microarray ,which contained specific probes of eleven pathogenic bacterium .Scanner was used to determinant the types of bacterium .Results The DNA microarray assay can detect 11 kinds of pathogenic bacterium specially .The sensitivity of the DNA may reach 2?0-3 ng .Conclusion To detect 11 kinds of pathogenic bacteria using DNA microarray combined with multiplex PCR is specific ,sensiu've ,practical.%目的 建立一种运用多重PCR方法结合基因芯片技术快速、准确检测11种常见致病菌的方法.方法 筛选志贺氏菌、肠炎沙门氏菌、伤寒沙门氏菌、大肠杆菌O157、副溶血性弧菌、普通变形杆菌、蜡样芽孢杆菌、金黄色葡萄球菌、单核细胞增生李斯特菌、产气荚膜梭菌、空肠弯曲菌的特异基因作为目的 基因.设计相应的引物及探针,进行多重PCR扩增,制备寡核苷酸芯片.将多重PCR扩增产物与带有11种特异探针的基因芯片杂交.用扫描仪扫描,判定细菌种类.结果 该基因芯片可特异性地检测11种致病菌,具有良好的特异性,基因组DNA检测灵敏度可达2×10-3ng.结论 多重PCR结合基因芯片技术检测11种不同致病菌的方法特异性好,灵敏度高,具有较好的实用性.

  11. Smoking, alcohol, diabetes, obesity, socioeconomic status, and the risk of colorectal cancer in a population-based case-control study.

    Science.gov (United States)

    Boyle, Terry; Fritschi, Lin; Tabatabaei, Seyed Mehdi; Ringwald, Kathrin; Heyworth, Jane S

    2014-12-01

    Although previous research has identified factors that may determine willingness to participate in research, relatively few studies have attempted to quantify the impact non-participation may have on exposure-disease associations. The aims of this study were to (a) investigate the associations between smoking, alcohol, diabetes, obesity, and socioeconomic status and the risk of colorectal cancer in a case-control study (59.7 and 47.2 % response fractions among cases and controls, respectively); and (b) perform sensitivity analyses to examine the possible influence of non-participation. Logistic regression was used to estimate the exposure-disease associations. We then investigated the associations between various demographic and health factors and the likelihood that an individual would participate in the case-control study and then performed two sensitivity analyses (sampling weights and multiple imputation) to examine whether non-participation bias may have influenced the exposure-disease associations. The exposures alcohol, smoking, and diabetes were associated with an increased risk of colorectal cancer. We found some differences between cases and controls when examining the factors associated with the participation in the study, and in the sensitivity analyses, the exposure-disease associations were slightly attenuated when compared with those from the original analysis. Non-participation may have biased the risk estimates away from the null, but generally not enough to change the conclusions of the study.

  12. Potential of eleven Eucalyptus species for the production of essential oils Potencial de onze espécies de eucalipto para a produção de óleos essenciais

    Directory of Open Access Journals (Sweden)

    Paulo Henrique Müller da Silva

    2006-02-01

    Full Text Available Most Eucalyptus plantations in Brazil aim the production of paper and charcoal, but the use of the species for lumbering, construction and extraction of essential oil has increased. Eleven species of Eucalyptus were assessed in regard to their essential oil production potential, nine never used before for commercial, essential oil extraction. Assessements were compared with Eucalyptus citriodora and Eucalyptus globulus, already explored in oil production for perfume and medical purposes, aiming to increase the availability of commercial species and the relationship between oil production and climatic conditions. Eucalyptus leaves were seasonally sampled (three months interval for distillation and determination of productivity and chemical composition of oil - contents of oils main components. Eucalyptus viminalis showed the highest potential for cineol, and standed out among the species not yet used commercially. Influenced by soil moisture contents and air temperature, the lowest and the highest oil production happened respectively in Spring and Summer. Water deficiency in Spring caused the lowest oil production. In the Summer, on the other hand, the highest oil production was observed when temperatures were higher and no water deficiency registered. There was no climatic influence on the main oil chemical component.A maioria das plantações de Eucalyptus brasileiras tem como objetivo a produção de papel e carvão, mas o uso das espécies para madeira, construção e extração de óleo essencial tem aumentado. Neste trabalho foram estudadas onze espécies de eucalipto quanto ao potencial para a obtenção de óleo essencial. Entre as espécies estudadas, nove não têm sido utilizadas na obtenção comercial de óleo. Para efeito comparativo, avaliou-se também duas outras espécies, o Eucalyptus citriodora e o Eucalyptus globulus, as quais são amplamente utilizadas, respectivamente, para a obtenção de óleo aromatizante e óleo para

  13. Chemical and instrumental characterization of pectin from dried pomace of eleven apple cultivars = Caracterização química e instrumental de pectinas isoladas de bagaço de 11 cultivares de maçã

    Directory of Open Access Journals (Sweden)

    Dayana Carla Rigoni

    2011-07-01

    Full Text Available Pectic substances from eleven samples of dried apple pomace were extracted using an acid procedure (100 mM HNO3, 10 min., 80ºC, dried, ground and stored in a P2O5 atmosphere. The degree of esterification was determined by the classical titrimetric method and confirmed by the instrumental FTIR method. The samples showed an average DE of 73% and the typical fingerprint in IR spectrogram. The steric exclusion chromatograms obtained with the multi-angle laser light scattering (MALLS and refraction index (RI detectors showed that all samples had a high molar fraction eluted at 36-38 min.,another large polysaccharide family had an elution time around 43 min, and some samples showed yet another low molecular oligosaccharide that appeared at 58-60 min. Gas chromatography of alditol acetate allowed estimates of the proportion of the neutral sugar in the samples. The ratio of galacturonic acid and rhamnose may give the average size of the galacturonan fraction. These results showed that yields of pectin extracted by the same acid procedure were slightly different. However, the degree of esterification of pectin was similar, with both factors pointing to the best sources in this group of varieties.Substâncias pécticas de 11 amostras de bagaço desidratado de maçã foram extraídas usando um procedimento ácido (HNO3 100 Mm, 10 min., 80oC, desidratadas, moídas e armazenadas em atmosfera de P2O5. O grau de esterificação das amostras foi determinado pelo método titulométrico, confirmado pelo instrumental FTIR. As amostras mostraram DE médio de 73% e o fingerprint característico no espectrograma em infravermelho. Os cromatogramas de exclusão estérica, obtidos com o detector para espalhamento multiangular de luz a laser (MALLS e com o índice de refração (RI, indicaram que todas as amostras apresentam fração de elevada massa molar, eluída a 36-38 min. e outra grande família de polissacarídeos com tempo de eluição de 43 min. Outros

  14. Determination of Common Metal Elements in Eleven-ingredients Shenqi Capsules by Inductively Coupled Plasma Mass Spectrometry%ICP-MS检测十一味参芪胶囊中常见金属元素

    Institute of Scientific and Technical Information of China (English)

    胡军高; 梁旭霞; 梁晓艳; 王晶; 陈光强

    2012-01-01

    common metal elements, ferrum(Fe), chromium(Cr), manganese(Mn), nickel(Ni), cuprum(Cu), zinc(Zn), arsenicum(As), argentums(Ag), chromium(Cd), stannum(Sn), stibine(Sb), barium(Ba), and plurabum(Pb), in Eleven-ingredient Shengqi Capsules, and to detect those elements in the capsules. Methods Three batches of Eleven-ingredient Shengqi Capsules were randomly sampled and weighed individually into 0.4 g. The three weighed samples were digested by wet method with concentrated nitric acid(HNO3) into colorless or yellowish solution, the metered volume being 10 mL. Based on online internal standards, the analysis method for common metal elements in the samples was set up. The accuracy and precision of the analysis method was verified with certified reference materials lyophilised beech leave powder and tea leaves. Common metal elements in the three batches of samples were analysed by inductively coupled plasma mass spectrometry(ICP-lV)S). The instrument parameters were below: radio frequency (RF) power at 1350 W, Barbinglon atomizer, carrier gas flow rate at 1.4 mL· min-1 sampling depth at 8.5 mm, Spectrum collection mode, and sample lifting speed at 0.4 L·min-1. Results The linear correlative coefficients for the common thirteen elements in the capsules were higher than 0.9990. The accuracy, precision and stability of the method were detected, and they all conformed to the analysis standard. RSD of within-day error was in the range of 0.50 %~4.56 %, and that of inter-day error was in the range of 1.17 %~5.03 %. Recoveries were 95.8 %~100.5 %(RSD being 1.82 %~2.68 %), 86.0 %~104.9 %(RSD being 1.70 %~6.33 %), 97.1 %~103.9 % (RSD being 2.51 %~5.19 %) and 92.1 %~110.0 %(RSD being 2.75 %~14.48 %) when the contents of metals were higher than 100 mg·kg-1, in the range of 1~100 mg·kg-1, 0.1~1 mg·kg-1 and lower than 0.1 mg·kg-1, respectively. Contents of Pb, Cd, Sn, Sb and Ag in the three batches of samples were lower than 1 mg·kg-1, Cr, Ni and Cu in the range of 1.3~4.6 mg·kg-1

  15. 妊娠合并慢性骨髓增殖性疾病11例临床分析%Clinical analysis of eleven patients with chronic myeloproliferative disorders complicating pregnancy

    Institute of Scientific and Technical Information of China (English)

    白月婷; 张超; 王建六; 梁梅英; 张晓红

    2010-01-01

    Objective To investigate the clinical characteristics, the antenatal management, the outcome and prognosis of chronic myeloproliferative disorders (CMPD) complicating pregnancy. Methods Retrospectively analyze the clinical data of eleven patients with CMPD complicating pregnancy hospitalized in Peking University People' s Hospital from 2000 to 2009, including five patients with essential thrombocythemia, one with primary myelofibrosis and five with chronic myeloid leukemia. Results (1)Five pregnancies had periodic antenatal care and laboratory monitorings like full blood count. Reasonable anti-coagulation therapy was given to prevent the complications. One patient with PMF diagnosed before conception had her first pregnancy ended with mild pre-eclampsia and intrauterine death at the gestational age of 32 weeks. During the first trimester of her second pregnancy two years later, the test for anti-β2 glycoprotein antibody was positive. She received low-dose aspirin and low-molecular-weight heparin as anticoagulants. An uneventful course was obtained and she delivered a healthy term infant. (2) Five pregnancies had occasional antenatal examination, including two patients with ET and three patients with CML One patient with ET developed severe pre-eclampsia at the gestational age of 25 weeks. Umbilical artery Doppler showed reversed end-diastolic velocity. The management with anti-convulsants, antihypertensives and anti-coagulants showed no effect. An emergency cesarean section had to be performed because of the aggressive hypertension and placental abruption, with still birth as a result. Two pregnancies never had an antenatal care. Both of them were admitted on labor and the diagnoses of CML were made. (3)Four pregnancies developed oligohydramnios and three developed preelampsia(two severe pre-eclampsia and one mild pre-eclampsia). There was no other hemorrhage and thrombosis event. (4) Eight pregnancies reached full-term with four cesarean sections and four vaginal

  16. "It's hard to tell": The challenges of scoring patients on standardised outcome measures by multidisciplinary teams: a case study of neurorehabilitation

    Directory of Open Access Journals (Sweden)

    Flynn R

    2008-10-01

    Full Text Available Abstract Background Interest is increasing in the application of standardised outcome measures in clinical practice. Measures designed for use in research may not be sufficiently precise to be used in monitoring individual patients. However, little is known about how clinicians and in particular, multidisciplinary teams, score patients using these measures. This paper explores the challenges faced by multidisciplinary teams in allocating scores on standardised outcome measures in clinical practice. Methods Qualitative case study of an inpatient neurorehabilitation team who routinely collected standardised outcome measures on their patients. Data were collected using non participant observation, fieldnotes and tape recordings of 16 multidisciplinary team meetings during which the measures were recited and scored. Eleven clinicians from a range of different professions were also interviewed. Data were analysed used grounded theory techniques. Results We identified a number of instances where scoring the patient was 'problematic'. In 'problematic' scoring, the scores were uncertain and subject to revision and adjustment. They sometimes required negotiation to agree on a shared understanding of concepts to be measured and the guidelines for scoring. Several factors gave rise to this problematic scoring. Team members' knowledge about patients' problems changed over time so that initial scores had to be revised or dismissed, creating an impression of deterioration when none had occurred. Patients had complex problems which could not easily be distinguished from each other and patients themselves varied in their ability to perform tasks over time and across different settings. Team members from different professions worked with patients in different ways and had different perspectives on patients' problems. This was particularly an issue in the scoring of concepts such as anxiety, depression, orientation, social integration and cognitive problems

  17. Apple pomace from eleven cultivars: an approach to identify sources of bioactive compounds = Bagaço de maçã de 11 cultivares: uma abordagem identificando fontes de compostos bioativos

    Directory of Open Access Journals (Sweden)

    Mariana Fátima Sato

    2010-01-01

    Full Text Available The dried apple pomace composition of eleven cultivars was assessed in this work. The drying process of apple pomace spread in a thin layer in the trays of an oven with circulating heated air at 60oC showed a 3rd order polynomial tendency and after 10 hours theproduct, with an equilibrium moisture of 10%, showed an homogeneous appearance according to colorimetric parameters. There are significant differences in the content of lipids, proteins,total titratable acids, total reducing sugars, dietetic fibers total phenol compounds and also in an oxidant activity. Total dietary fibers include pectin, 35%, and insoluble fibers (65%. The contentof total phenolic compound, determined with the Folin Ciocalteu reagent and expressed as catechin, goes from 2.29 to 7.15 g kg-1 of dried apple pomace and the antioxidant capacity, expressed as total equivalent (TEAC, from 17.41 to 77.48 mMol g-1. A correlation of 82%between both these quality factors was found. The principal component analysis established the efficiency of total phenol compound, antioxidative capacity, total fiber and total reducing sugarsto identify the best cultivar set as source of bioactive compound. Cv. M-2/00 shows high content of total phenol compound and antioxidant capacity, cv. Catarina, of pectin while cv. MRC 11/95,M-12/00, M-8/00, M6/00 e M-11/00, of malic acid and of total reducing sugars. The other cultivars show high content of fibers, ashes and lipids.A composição do bagaço seco de maçã de 11 novas cultivares foi determinada neste trabalho. A secagem do bagaço de maçã disposto em camada fina em estufa de secagem por convecção com ar aquecido a 60oC apresentou uma tendência polinomial cúbica e após 10 horas o produto continha uma umidade de equilíbrio de 10% com uma aparência homogêna, conforme parâmetros colorimétricos, sem evidências de superaquecimento. Houve diferenças significativas entre os teores de lipídeos, de ácido malico, de compostos fen

  18. Determination of diets for the populations of eleven regions of the European community to be used for obtaining radioactive contamination levels. First results concerning the food consumption of individuals classified in nine age-groups; Determination des regimes alimentaires des populations de onze regions de la Communaute Europenne et vue de l'etude des niveaux de contamination radioactive. Premiere serie de resultats concernant la consommation alimentaire des individus groupes en neuf classes d'ages

    Energy Technology Data Exchange (ETDEWEB)

    Ledermann, S.; Lacourly, G.; Garnier, A.; Cresta, M.; Lombardo, E. [Commissariat a l' Energie Atomique, 92 - Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1968-07-01

    The present document continues the report CEA-R--2979 - EUR--2768-f. The processing of the data given by the family food enquiry carried out in eleven regions of the European Community, has permitted to determine the food consumption of individuals classified in nine age-groups, in order to study the radioactive contamination levels in the food-chain. The used statistical method is described, and the obtained results are presented in form of double-entry tables giving for each region and for each age-group the mean weekly food-consumption and the contribution of each diet in nutrition principles, in minerals, vitamins, trace elements and calories. (authors) [French] Ce rapport fait suite au rapport CEA-R--2979 - EUR--2768-f. Le traitement de l'information apportee par les enquetes alimentaires familiales realisees dans onze regions de la Communaute Europeenne a permis de determiner les consommations alimentaires des individus groupes en neuf classes d'age, en vue de l'etude des niveaux de contamination radioactive dans les chaines alimentaires. La methode statistique employee est decrite et les resultats obtenus sont presentes sous forme de tableaux a double entree donnant pour chacune des regions etudiees et pour chacune des neuf classes d'age, les consommations moyennes hebdomadaires, ainsi que les apports en principes nutritifs, mineraux, vitamines et oligo-elements, et calories de chaque regime. (auteurs)

  19. Assessment of participation bias in cohort studies: systematic review and meta-regression analysis.

    Science.gov (United States)

    Silva Junior, Sérgio Henrique Almeida da; Santos, Simone M; Coeli, Cláudia Medina; Carvalho, Marilia Sá

    2015-11-01

    The proportion of non-participation in cohort studies, if associated with both the exposure and the probability of occurrence of the event, can introduce bias in the estimates of interest. The aim of this study is to evaluate the impact of participation and its characteristics in longitudinal studies. A systematic review (MEDLINE, Scopus and Web of Science) for articles describing the proportion of participation in the baseline of cohort studies was performed. Among the 2,964 initially identified, 50 were selected. The average proportion of participation was 64.7%. Using a meta-regression model with mixed effects, only age, year of baseline contact and study region (borderline) were associated with participation. Considering the decrease in participation in recent years, and the cost of cohort studies, it is essential to gather information to assess the potential for non-participation, before committing resources. Finally, journals should require the presentation of this information in the papers.

  20. Assessment of participation bias in cohort studies: systematic review and meta-regression analysis

    Directory of Open Access Journals (Sweden)

    Sérgio Henrique Almeida da Silva Junior

    2015-11-01

    Full Text Available Abstract The proportion of non-participation in cohort studies, if associated with both the exposure and the probability of occurrence of the event, can introduce bias in the estimates of interest. The aim of this study is to evaluate the impact of participation and its characteristics in longitudinal studies. A systematic review (MEDLINE, Scopus and Web of Science for articles describing the proportion of participation in the baseline of cohort studies was performed. Among the 2,964 initially identified, 50 were selected. The average proportion of participation was 64.7%. Using a meta-regression model with mixed effects, only age, year of baseline contact and study region (borderline were associated with participation. Considering the decrease in participation in recent years, and the cost of cohort studies, it is essential to gather information to assess the potential for non-participation, before committing resources. Finally, journals should require the presentation of this information in the papers.

  1. Overview of the Dissertation Process within the Framework of Flow Theory: A Qualitative Study

    Science.gov (United States)

    Cakmak, Esra; Oztekin, Ozge; Isci, Sabiha; Danisman, Sahin; Uslu, Fatma; Karadag, Engin

    2015-01-01

    The purpose of this study is to examine the flow of doctoral students who are also research assistants and in the dissertation process. The study was designed using the case study method. The case undertaken in the study was the dissertation process. Eleven participants were selected into the study using maximum variation sampling. Face-to-face,…

  2. The Cross-sectional Investigation on Growth and Development of Children Aged Eight to Eleven from Migrant Workers' Family in Shenyang City%沈阳市8~11岁农民工子女生长发育的横断面调查

    Institute of Scientific and Technical Information of China (English)

    李赫; 周宝森

    2011-01-01

    Objective To find out the growth and development of the children from migrant workers' family in Shenyang city,as well as providing corresponding information for health service work. Methods According to principles of stratified and cluster sampling,the paper selected five elementary schools among the schools which receive the children of migrant workers in Shenhe district,Tiexi district and Dadong district of Shenyang city as samples. This investigation selected seven hundred children aged eight to eleven from migrant workers and urban children in those five elementary schools,and taking their height,body weight,chest circumference,vital capacity,body mass index,chest circumference/height index and vital capacity/weight index as the objects of study in comparative analysis. Results The statistics showed that the mean of the growth and development parameters of most children form migrant workers were much lower than that of urban children. Conclusion It proved that the levels of the growth and development of children from migrant workers' family were lower than that of urban children. As a result,not only the promotion of healthy condition for the children from migrant workers should be enhanced,but the living condition of them as well. We should improve the level of the growth and development of children from migrant workers.%目的 了解沈阳市农民工子女生长发育状况,为卫生服务工作提供相应的依据.方法 调查按分层整群抽样原则,在沈阳市沈河区、铁西区和大东区接收农民工子女的学校中随机抽取5所小学,以8~11岁的农民工子女和城市儿童共700人作为调查对象,对身高、体质量、胸围、肺活量、体质指数、身高胸围指数和肺活量指数进行对比分析.结果 农民工子女大部分的生长发育指标、指数均值低于城市儿童.结论 农民工子女生长发育水平低于城市儿童,因此应加强农民工子女的健康促进工作,改善其生存状况,

  3. Study Guide for Fundamentals of Solar Heating: A Correspondence Course for the Airconditioning Industry.

    Science.gov (United States)

    Sheet Metal and Air Conditioning Contractors National Association, Vienna, VA.

    This study guide groups eleven lessons into four study units. The first unit discusses the development and basic concepts of solar heating. The second unit deals with the nomenclature of the solar heating system. The third study unit covers sizing of the solar heating system to meet demand and discusses the operation of the total system. The…

  4. Kommunikation kring elevens förkunskap som en del av den formativa bedömningenCommunication about pupils´ prior knowledge as a part of formative assessment

    Directory of Open Access Journals (Sweden)

    Ann-Catherine Henriksson

    2015-05-01

    Full Text Available Communicating pupils´ prior understanding and knowledge is essential when you look upon learning from a constructivist point of view. Formative assessment is an important factor influencing learningand making learning visible for the pupil and the teacher. This qualitative study focuses on how primary school teachers look upon communicating the pupils´ prior understanding and knowledge in the science subjects. The main aim of the study is to clarify class-teachers´ perceptions of communication about pupils´ prior knowledge according to the extent and the form. The semi-structured interviews were conducted in spring 2012. The teachers´ perceptions of communication about the pupils´ prior knowledge can as a result from this study be categorized into four different categories: 1. A structured control considering both the students and the teacher’s awareness. 2. A discussion about the upcoming theme. 3. The teacher feels that he or she is aware of the knowledge level without communication. 4. Avoidance of discussion and control because the teacher feels unsecure about his or her own subject knowledge. The research implies that because teaching science in very heterogeneous classes can be challenging the teachers seem to need more knowledge about how to improve the quality of formative assessment. Further, they need more knowledge about what benefits you as a teacher and the pupils get from using formative assessment.

  5. Hyperoxia increases arterial oxygen pressure during exercise in type 2 diabetes patients: A feasibility study

    NARCIS (Netherlands)

    R. Rozenberg (Robert); R.T. Mankowski (Robert T.); L.J.C. van Loon (Luc); J.G. Langendonk (Janneke); E.J.G. Sijbrands (Eric); A.H. van den Meiracker (Anton); H.J. Stam (Henk); S.F.E. Praet (Stephan)

    2016-01-01

    textabstractObjective: The study investigated the feasibility and potential outcome measures during acute hyperoxia in type 2 diabetes patients (DM2). Methods: Eleven DM2 patients (7 men and 4 women) were included in the study. The patients cycled (30 min at 20 % Wmax) whilst breathing three

  6. Research and Trends in the Studies of Homeschooling Practices: A Review on Selected Journals

    Science.gov (United States)

    Jamaludin, Khairul Azhar; Alias, Norlidah; DeWitt, Dorothy

    2015-01-01

    The practice of homeschooling still receives contrasting responses on its relevancy and effectiveness. The current study is aimed to map the trends in the selected eleven studies from various educational journals. The analysis focuses on mapping the trends on: a) research settings, b) target sample, c) method or instrument used, d) common focus or…

  7. Multi-residue determination of eleven anticoagulant rodenticides by high-performance liquid chromatography with diode array/fluorimetric detection: investigation of suspected animal poisoning in the period 2012-2013 in north-eastern Italy.

    Science.gov (United States)

    Gallocchio, Federica; Basilicata, Lara; Benetti, Cristiana; Angeletti, Roberto; Binato, Giovanni

    2014-11-01

    Misuse or deliberate abuse of anticoagulant rodenticides (AR) may often result in incidental or malicious non-target animal poisoning. This study presents preliminary results of the analysis of 561 real suspected samples, ranging from baits to livers and stomach contents, collected at the Istituto Zooprofilattico Sperimentale delle Venezie (official referral laboratory for the regions of north-eastern Italy), in the period 2012-2013. Samples were analyzed by a method based on a combination of liquid chromatography with diode array/fluorescence detection (HPLC-DAD/F) able to identify 11 different AR (brodifacoum, bromadiolone, chloropahacinone, coumachlor, coumafuryl, coumatetralyl, difenacoum, diphacinone, flocoumafen, pindone, warfarin). Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  8. Estimation of the true ileal digestible lysine and sulfur amino acid requirement and comparison of the bioefficacy of 2-hydroxy-4-(methylthio)butanoic acid and DL-methionine in eleven- to twenty-six-kilogram nursery pigs.

    Science.gov (United States)

    Yi, G F; Gaines, A M; Ratliff, B W; Srichana, P; Allee, G L; Perryman, K R; Knight, C D

    2006-07-01

    Three experiments were conducted to determine the true ileal digestible (TID) Lys and sulfur AA (SAA) requirement and to compare the bioefficacy of 2-hydroxy-4-(methylthio)butanoic acid (HMTBA) and dl-MET as Met sources in nursery pigs. Experiment 1 included 2 studies: 1 was 662 nursery pigs (Triumph 4 x PIC C22; initial BW 12.2 +/- 0.18 kg) allotted to 1 of 5 dietary treatments with TID Lys concentrations ranging from 1.10 to 1.50%; and the second study was 665 nursery pigs (Triumph 4 x PIC C22; initial BW 12.3 +/- 0.18 kg) allotted to 1 of 5 dietary treatments with TID SAA concentration ranging from 0.63 to 0.90%. In Exp. 2, 638 nursery pigs (Triumph 4 x PIC C22; initial BW 13.0 +/- 0.16 kg) were allotted to the same 5 SAA dietary treatments as in Exp. 1. In Exp. 3, 1,232 pigs (Triumph 4 x PIC C22; initial BW 11.0 +/- 0.30 kg) were allotted to 1 of 7 dietary treatments. The basal diet (diet 1) was supplemented with high concentrations of synthetic AA but no Met; this resulted in a dietary concentration of TID Lys of 1.30% and TID SAA of 0.50%. Diets 2 to 7 were the basal diet supplemented with 3 equimolar levels of HMTBA or dl-MET to provide TID SAA concentrations of 0.56, 0.62, and 0.68%, respectively. In Exp. 1, increasing TID Lys from 1.10 to 1.50% increased ADG (quadratic; P < 0.05) and improved G:F (linear; P < 0.002). The pooled data of Exp. 1 (SAA study) and Exp. 2 indicated that increasing TID SAA from 0.63 to 0.90% increased ADG (quadratic; P < 0.01) and improved G:F (quadratic; P < 0.01). Various methods of analyzing the growth response surface indicated that the optimal TID Lys concentration ranged from 1.28 to 1.32% for ADG (Exp. 1), and the optimal TID SAA concentration ranged from 0.73 to 0.77% for ADG and 0.80 to 0.83% for G:F (pooled Exp. 1 and 2), respectively. In Exp. 3, increasing TID SAA concentrations from 0.50 to 0.68% resulted in a linear improvement of ADG (P < 0.001), ADFI (P < 0.05), and G:F (P < 0.001). The best fit comparison of HMTBA

  9. Experimental Toxoplasmosis in Rats Induced Orally with Eleven Strains of Toxoplasma gondii of Seven Genotypes: Tissue Tropism, Tissue Cyst Size, Neural Lesions, Tissue Cyst Rupture without Reactivation, and Ocular Lesions.

    Science.gov (United States)

    Dubey, Jitender P; Ferreira, Leandra R; Alsaad, Mohammad; Verma, Shiv K; Alves, Derron A; Holland, Gary N; McConkey, Glenn A

    2016-01-01

    The protozoan parasite Toxoplasma gondii is one of the most widely distributed and successful parasites. Toxoplasma gondii alters rodent behavior such that infected rodents reverse their fear of cat odor, and indeed are attracted rather than repelled by feline urine. The location of the parasite encysted in the brain may influence this behavior. However, most studies are based on the highly susceptible rodent, the mouse. Latent toxoplasmosis was induced in rats (10 rats per T. gondii strains) of the same age, strain, and sex, after oral inoculation with oocysts (natural route and natural stage of infection) of 11 T. gondii strains of seven genotypes. Rats were euthanized at two months post inoculation (p.i.) to investigate whether the parasite genotype affects the distribution, location, tissue cyst size, or lesions. Tissue cysts were enumerated in different regions of the brains, both in histological sections as well in saline homogenates. Tissue cysts were found in all regions of the brain. The tissue cyst density in different brain regions varied extensively between rats with many regions highly infected in some animals. Overall, the colliculus was most highly infected although there was a large amount of variability. The cerebral cortex, thalamus, and cerebellum had higher tissue cyst densities and two strains exhibited tropism for the colliculus and olfactory bulb. Histologically, lesions were confined to the brain and eyes. Tissue cyst rupture was frequent with no clear evidence for reactivation of tachyzoites. Ocular lesions were found in 23 (25%) of 92 rat eyes at two months p.i. The predominant lesion was focal inflammation in the retina. Tissue cysts were seen in the sclera of one and in the optic nerve of two rats. The choroid was not affected. Only tissue cysts, not active tachyzoite infections, were detected. Tissue cysts were seen in histological sections of tongue of 20 rats but not in myocardium and leg muscle. This study reevaluated in depth the

  10. Cobertura do teste de Papanicolaou e fatores associados à não-realização: um olhar sobre o Programa de Prevenção do Câncer do Colo do Útero em Pernambuco, Brasil Pap smear coverage and factors associated with non-participation in cervical cancer screening: an analysis of the Cervical Cancer Prevention Program in Pernambuco State, Brazil

    Directory of Open Access Journals (Sweden)

    Kamila Matos de Albuquerque

    2009-01-01

    Full Text Available Buscou-se avaliar a cobertura do teste Papanicolaou no Estado de Pernambuco, Brasil, nos três anos anteriores à pesquisa, entre mulheres de 18-69 anos, e identificar fatores associados à sua não-realização. Trata-se de um estudo transversal, de base populacional, utilizando-se dados de inquérito realizado no período 2005-2006 com 640 indivíduos, selecionados por amostragem por conglomerados em três estágios de seleção. Foram analisadas informações sobre 258 mulheres. A cobertura do Papanicolaou entre mulheres de 18-69 anos foi de 58,7% e de 25-59 anos de 66,2%. Viver sem companheiro, não ter dado à luz e não ter realizado consulta médica no último ano mostraram associação com a não-realização do teste. Na análise multivariada, o baixo grau de escolaridade mostrou também efeito significativo. A cobertura do Papani-colaou em Pernambuco foi satisfatória, porém insuficiente para impactar no perfil epidemiológico do câncer do colo uterino. É preciso fortalecer e qualificar as ações de promoção da saúde, visando reduzir as desigualdades e estimular o protagonismo das mulheres nas ações de prevenção do câncer do colo uterino.This research aimed to assess coverage of Pap smear screening in the State of Pernambuco, Brazil, during the three years prior to the study, among women 18 to 69 years of age, and to identify factors associated with women's lack of participation in screening. This was a cross-sectional, population-based study, using data from a survey in 2005-2006 with 640 women, selected by three-stage cluster sampling. Information on 258 women was analyzed. Pap smear coverage was 58.7% for women 18 to 69 years of age and 66.2% for those 25 to 59. Single marital status, no history of childbirth, and not having consulted a physician in the previous year were associated with lack of Pap smear screening. In the multivariate analysis, low schooling also showed a significant effect. Pap smear coverage in

  11. Gas chromatography-tandem mass spectrometry assay for the quantification of four benzodiazepines and citalopram in eleven postmortem rabbit fluids and tissues, with application to animal and human samples.

    Science.gov (United States)

    Cartiser, N; Bévalot, F; Le Meur, C; Gaillard, Y; Malicier, D; Hubert, N; Guitton, J

    2011-10-01

    Pharmacokinetic studies and postmortem toxicological investigations require a validated analytical technique to quantify drugs on a large number of matrices. Three-step liquid/liquid extraction with online derivatization (silylation) ahead of analysis by gas chromatography-tandem mass spectrometry was developed and validated on rabbit specimens in order to quantify citalopram and 4 benzodiazepines (diazepam, nordazepam, oxazepam and temazepam) in 11 biological matrices (blood, urine, bile, vitreous humor, liver, kidney, skeletal muscle, brain, adipose tissue, bone marrow (BM) and lung). Since the 11 biological matrices came from the same animal species, full validation was performed on 1 matrix, bone marrow (considered the most complex), while the other 10 underwent partial validation. Due to non-negligible matrix effects, calibration curves were performed on each matrix. Within-day and between-day precision (less than 12.0% and 12.6%, respectively) and accuracy (from 88.9% to 106.4%) were acceptable on BM at both low and high concentrations. Assessment on the other matrices confirmed accuracy and within-day precision (less than 12%, and generally between 85.1% and 114.5%, respectively). The lower limit of quantification of the method was 1ng/g for nordazepam, 5ng/g for citalopram and 10ng/g for oxazepam, diazepam and temazepam. The combination of 3-step extraction and MS/MS detection provided good selectivity in all matrices, including the most lipid-rich. Application to real-case samples showed that the method was sensitive enough to describe distribution patterns in an animal experiment, and specific enough to detect molecules in highly putrefied samples from human postmortem cases.

  12. ACOSS Eleven (Active Control of Space Structures). Volume 1.

    Science.gov (United States)

    1983-07-01

    frequencies near 1/(2TNya)," and T 0.8 TNyq "if power spectra measure- ments are of prime consideration" (compare these to Sections 2.5 and 2.3... entropy method as in [2-151, are not appropriate techniques for spectral estimation of sampled data. Any failure of these methods in spectral estima... SVD ), or the QR factorization [2-22], is of secondary importance. To demonstrate the preceding discussion and to establish rules for choosing T*, we

  13. Advanced Chemical Characterization and Physical Properties of Eleven Lubricants.

    Science.gov (United States)

    1983-03-01

    Mod) Specific Heat, Differential Section Six, DSC and Pressure* Scanning DSC Cells and Accessories/ Calorimetric Method Instruction Manual 990 Thermal...Ie bellow shows tCi calculated and literature values for sapphire at the three temperatures of interest. °C Cp (calc.) Cp (lit) 82 0.225 0.219 (380K...The modification enables the extension of the upper tempera - ture limit as defined by the ASTM D 2887 procedure. This modification is presently being

  14. Galaxy Evolution Over the Past Eleven Billion Years

    DEFF Research Database (Denmark)

    Man, Wing Shan

    in the deepest Hubble Space Telescope (HST) optical surveys. Their stellar populations, characterized using deep near-infrared photometric and spectroscopic observations, reveal that they are the most massive and evolved galaxies at early epochs. This suggests that they have undergone a rapid build-up of stellar...

  15. Living with Volcanoes: Year Eleven Teaching Resource Unit.

    Science.gov (United States)

    Le Heron, Kiri; Andrews, Jill; Hooks, Stacey; Larnder, Michele; Le Heron, Richard

    2000-01-01

    Presents a unit on volcanoes and experiences with volcanoes that helps students develop geography skills. Focuses on four volcanoes: (1) Rangitoto Island; (2) Lake Pupuke; (3) Mount Smart; and (4) One Tree Hill. Includes an answer sheet and resources to use with the unit. (CMK)

  16. 76 FR 54732 - Eleven Point Resource Advisory Committee

    Science.gov (United States)

    2011-09-02

    ... inspection and copying. The public may inspect comments received at Mark Twain National Forest Supervisors... Committee Coordinator, Mark Twain National Forest, 573-341- 7404, rrhall@fs.fed.us . Individuals who...

  17. 75 FR 28234 - Eleven Point Resource Advisory Committee

    Science.gov (United States)

    2010-05-20

    ... Whittekiend, Designated Federal Official, Mark Twain National Forest, 401 Fairgrounds Road, Rolla, MO... public inspection and copying. The public may inspect comments received at Mark Twain National Forest... Advisory Committee Coordinator, Mark Twain National Forest, 573-341- 7404. Individuals who...

  18. 75 FR 38457 - Eleven Point Resource Advisory Committee

    Science.gov (United States)

    2010-07-02

    ... Federal Official, Mark Twain National Forest, 401 Fairgrounds Road, Rolla, MO. Comments may also be sent... copying. The public may inspect comments received at Mark Twain National Forest Supervisors Office, 401... Coordinator, Mark Twain National Forest, 573-341- 7404. Individuals who use telecommunication devices for...

  19. 76 FR 1402 - Eleven Point Resource Advisory Committee

    Science.gov (United States)

    2011-01-10

    ..., Designated Federal Official, Mark Twain National Forest, 401 Fairgrounds Road, Rolla, MO. Comments may also... inspection and copying. The public may inspect comments received at Mark Twain National Forest Supervisors... Advisory Committee Coordinator, Mark Twain National Forest, 573-341- 7404. Individuals who...

  20. 76 FR 16726 - Eleven Point Resource Advisory Committee

    Science.gov (United States)

    2011-03-25

    ... Federal Official, Mark Twain National Forest, 401 Fairgrounds Road, Rolla, MO. Comments may also be sent... copying. The public may inspect comments received at Mark Twain National Forest Supervisors Office, 401... Coordinator, Mark Twain National Forest, 573-341- 7404. Individuals who use telecommunication devices for...

  1. 75 FR 47535 - Eleven Point Resource Advisory Committee

    Science.gov (United States)

    2010-08-06

    ... Whittekiend, Designated Federal Official, Mark Twain National Forest, 401 Fairgrounds Road, Rolla, MO... public inspection and copying. The public may inspect comments received at Mark Twain National Forest... Advisory Committee Coordinator, Mark Twain National Forest, 573-341- 7404. Individuals who...

  2. 75 FR 59680 - Eleven Point Resource Advisory Committee

    Science.gov (United States)

    2010-09-28

    ..., Designated Federal Official, Mark Twain National Forest, 401 Fairgrounds Road, Rolla, MO. Comments may also... inspection and copying. The public may inspect comments received at Mark Twain National Forest Supervisors... Advisory Committee Coordinator, Mark Twain National Forest, 573-341- 7404. Individuals who...

  3. 77 FR 55799 - Eleven Point Resource Advisory Committee

    Science.gov (United States)

    2012-09-11

    ... inspection and copying. The public may inspect comments received at Mark Twain National Forest Supervisor's... Committee Coordinator, Mark Twain National Forest, 573-341- 7404, rrhall@fs.fed.us . Individuals who...

  4. 75 FR 71068 - Eleven Point Resource Advisory Committee

    Science.gov (United States)

    2010-11-22

    ..., Designated Federal Official, Mark Twain National Forest, 401 Fairgrounds Road, Rolla, MO. ] Comments may also... inspection and copying. The public may inspect comments received at Mark Twain National Forest Supervisors... Advisory Committee Coordinator, Mark Twain National Forest, 573-341- 7404. Individuals who...

  5. Complementation analysis of eleven tryptophanase mutations in Escherichia coli.

    Science.gov (United States)

    White, M K; Yudkin, M D

    1979-10-01

    Nine independent mutants deficient in tryptophanase activity were isolated. Each mutation was transferred to a specialized transducing phage that carries the tryptophanase region of the Escherichia coli chromosome. The nine phages thus produced, and a tenth carrying a previously characterized tryptophanase mutation, were used to lysogenize a bacterial strain harbouring a mutation in the tryptophanase structural gene and also a suppressor of polarity. In no case was complementation observed; we conclude that there is no closely linked positive regulatory gene for tryptophanase.

  6. Comparative embryology of eleven species of stony corals (Scleractinia.

    Directory of Open Access Journals (Sweden)

    Nami Okubo

    Full Text Available A comprehensive understanding of coral reproduction and development is needed because corals are threatened in many ways by human activity. Major threats include the loss of their photosynthetic symbionts (Symbiodinium caused by rising temperatures (bleaching, reduced ability to calcify caused by ocean acidification, increased storm severity associated with global climate change and an increase in predators caused by runoff from human agricultural activity. In spite of these threats, detailed descriptions of embryonic development are not available for many coral species. The current consensus is that there are two major groups of stony corals, the "complex" and the "robust". In this paper we describe the embryonic development of four "complex" species, Pseudosiderastrea tayamai, Galaxea fascicularis, Montipora hispida, and Pavona Decussata, and seven "robust" species, Oulastrea crispata, Platygyra contorta, Favites abdita, Echinophyllia aspera, Goniastrea favulus, Dipsastraea speciosa (previously Favia speciosa, and Phymastrea valenciennesi (previously Montastrea valenciennesi. Data from both histologically sectioned embryos and whole mounts are presented. One apparent difference between these two major groups is that before gastrulation the cells of the complex corals thus far described (mainly Acropora species spread and flatten to produce the so-called prawn chip, which lacks a blastocoel. Our present broad survey of robust and complex corals reveals that prawn chip formation is not a synapomorphy of complex corals, as Pavona Decussata does not form a prawn chip and has a well-developed blastocoel. Although prawn chip formation cannot be used to separate the two clades, none of the robust corals which we surveyed has such a stage. Many robust coral embryos pass through two periods of invagination, separated by a return to a spherical shape. However, only the second of these periods is associated with endoderm formation. We have therefore termed the first invagination a pseudo-blastopore.

  7. Eleven Efficiency Boosters for AutoCAD 2014

    National Research Council Canada - National Science Library

    Lynn Allen

    2014-01-01

      3. Nicely numbered layers. AutoCAD has also learned to count! You'll find that numbered layer names are now listed in their natural order, such as 1, 2, 4, 5, 10, 21, and 25, as opposed to listing them as 1, 10, 2, 21, 25, 4, and 5...

  8. Mounier-Kuhn syndrome (tracheobronchomegaly): An analysis of eleven cases.

    Science.gov (United States)

    Akgedik, Recep; Karamanli, Harun; Kizilirmak, Deniz; Kurt, Ali Bekir; Öztürk, Hasan; Yildirim, Berna Botan; Çakir, Lütfullah

    2016-12-27

    Mounier-Kuhn syndrome (MKS) is a congenital disorder characterized by tracheobronchomegaly resulting from the absence of elastic fibers in the trachea and main bronchi or atrophy and thinning of the smooth muscle layer. In this syndrome, dead space associated with tracheobronchomegaly increases and discharge of secretions decreases because of ineffective coughing. The most common complications are recurrent lower respiratory tract infections and bronchiectasis. We examined the clinical characteristics, radiological features, and related complications of patients with MKS. The cases were obtained between September 2007 and November 2015. Computed tomography scans of the chest were used to diagnose tracheobronchomegaly. All cases (a total of 11) were males with a mean age of 63 ± 13 (range, 38-80) years. The mean diameter of the trachea was 31.53 ± 2.99 mm; the mean transverse diameter was 31.69 ± 3.10 mm and the mean sagittal diameter was 31.36 ± 3.01 mm. Complaints at the time of presentation included chronic cough, purulent sputum, dyspnea, and hemoptysis. There were recurrent pulmonary infections in seven cases, bronchiectasis in six, and tracheal diverticulum in four at the time of diagnosis. In this article, 11 cases with various rarely seen complications are presented and evaluated in the light of current literature. We recommend that if chronic cough, recurrent pulmonary infections, and bronchiectasis seen in a patient, MKS should be kept in mind. © 2017 John Wiley & Sons Ltd.

  9. Lesson Eleven Transient and intermittent left bundle branch block

    Institute of Scientific and Technical Information of China (English)

    鲁端; 王劲

    2004-01-01

    @@ In transient left bundle branch block,normal intraventricular conduction subsequently returns,if only1temporarily.The condition has also been called paroxysmal,unstable,or temporary left bundle branch block. Its etiology is similar to that of the stable variety2, with the great majority of the patients having ischemic or hypertensive heart disease or both. Transient bundle branch block may complicate acute myocardial infarction or may occur during attacks of angina. It may appear during an episode of congestive heart failure and disappear with improvement of the cardiac status. Most patients eventually develop permanent block. Occasionally,however, the patient may revert to normal conduction even years after consistently demonstrating the block.

  10. LEP shuts down after eleven years of forefront research

    CERN Multimedia

    2000-01-01

    After extended consultation with the appropriate scientific committees, CERN’s Director-General Luciano Maiani announced today that the LEP accelerator had been switched off for the last time. LEP was scheduled to close at the end of September 2000 but tantalising signs of possible new physics led to LEP’s run being extended until 2 November. At the end of this extra period, the four LEP experiments had produced a number of collisions compatible with the production of Higgs particles with a mass of around 115 GeV. These events were also compatible with other known processes. The new data was not sufficiently conclusive to justify running LEP in 2001, which would have inevitable impact on LHC construction and CERN’s scientific programme. The CERN Management decided that the best policy for the Laboratory is to proceed full-speed ahead with the Large Hadron Collider (LHC) project. Steve Myers, Head of SL Division, with members of the LEP team, pulling the symbolic rope to swich off the accelerator. CERN Co...

  11. The ELM Survey. VI. Eleven New Double Degenerates

    CERN Document Server

    Gianninas, A; Brown, Warren R; Canton, Paul; Kenyon, Scott J

    2015-01-01

    We present the discovery of 11 new double degenerate systems containing extremely low-mass white dwarfs (ELM WDs). Our radial velocity observations confirm that all of the targets have orbital periods $\\leq$ 1 day. We perform spectroscopic fits and provide a complete set of physical and binary parameters. We review and compare recent evolutionary calculations and estimate that the systematic uncertainty in our mass determinations due to differences in the evolutionary models is small ($\\approx$ 0.01 M$_{\\odot}$). Five of the new systems will merge due to gravitational wave radiation within a Hubble time, bringing the total number of merger systems found in the ELM Survey to 38. We examine the ensemble properties of the current sample of ELM WD binaries, including the period distribution as a function of effective temperature, and the implications for the future evolution of these systems. We also revisit the empirical boundaries of instability strip of ELM WDs and identify new pulsating ELM WD candidates. Fin...

  12. Galaxy Evolution Over the Past Eleven Billion Years

    DEFF Research Database (Denmark)

    Man, Wing Shan

    mass followed by a short-lived, effective phase of star formation quenching. Curiously, their stellar densities are an order of magnitude higher than their local counterparts, containing 1011 solar masses within a radius of only 1.5 kpc. No similar galaxies exist in the local Universe, therefore...

  13. Eleven Tribes Jump START Clean Energy Projects, Summer 2012 (Newsletter)

    Energy Technology Data Exchange (ETDEWEB)

    2012-06-01

    This newsletter describes key activities of the DOE Office of Indian Energy Policy and Programs for Summer 2012. The U.S. Department of Energy Office of Indian Energy Policy and Programs (DOE-IE) has selected 11 Tribes - five in Alaska and six in the contiguous United States - to receive on-the-ground technical support for community-based energy efficiency and renewable energy projects as part of DOE-IE's Strategic Technical Assistance Response Team (START) Program. START finalists were selected based on the clarity of their requests for technical assistance and the ability of START to successfully work with their projects or community. Technical experts from DOE and its National Renewable Energy Laboratory (NREL) will work directly with community-based project teams to analyze local energy issues and assist the Tribes in moving their projects forward. In Alaska, the effort will be bolstered by DOE-IE's partnership with the Denali Commission, which will provide additional assistance and expertise, as well as funding to fuel the Alaska START initiative.

  14. Få blik for elevens læring og trivsel

    DEFF Research Database (Denmark)

    Nissen, Poul

    2016-01-01

    Præsentation af to digitaliserede ultra korte analoge rating skalaer til brug for Android, iphone, tablets, pc, læringsskalaen og trivselsskalaen i forbindelse med måling af læring og trivsel.......Præsentation af to digitaliserede ultra korte analoge rating skalaer til brug for Android, iphone, tablets, pc, læringsskalaen og trivselsskalaen i forbindelse med måling af læring og trivsel....

  15. Review - Critical Han Studies

    Directory of Open Access Journals (Sweden)

    Zhiguo Ye

    2013-12-01

    Full Text Available Review of: Thomas Mullaney, James Leibold, Stéphane Gros, and Eric Armand Vanden Bussche (eds. 2012. Critical Han Studies: The History, Representation, and Identity of China's Majority. Berkeley, Calif: University of California Press. This path-breaking volume is an academic collaboration that emerged out of the "Critical Han Studies Conference and Workshop" at Stanford University in April 2008. Eleven scholars contributed to the question of what it means to be 'Han' in China, both historically and at present. Constituting over ninety percent of China's population, the Han are not only the largest ethnic group in China, but are also one of the largest categories of collective identity in the world. Despite this, the dominant Han group has so far eluded careful scholarly scrutiny, with the Han often referred to as an unmarked majority category in contemporary China. This volume challenges such conventional views by conceptualizing new interdisciplinary approaches to the question of Hanness. The eleven essays of the volume are divided into three themes: 'Han and China', 'The Problem of Han Origins', and 'The Problem of Han Formations'. The first theme, comprised of four essays, analyzes the ties that bind the category of Han to those of Chinese ethnicity, race, and polity. Kevin Carrico in "Recentering China: The Cantonese in and Beyond the Han" questions a single, unitary Hanness that he believes conceals "countless other perceived and imagined lines of differentiation" (25. The study examines how multiple identities...

  16. Twenty-Two Hispanic Leaders Discuss Poverty: Results from the Hispanic Leaders Study. Final Version.

    Science.gov (United States)

    Quiroz, Julia Teresa

    This study examines the perceptions of 22 national Hispanic American leaders about poverty among Hispanics. Eleven of the leaders were Mexican American; five were Puerto Rican; four were Cuban American; one was Central American; and one was South American. Twelve of the leaders were heads of public interest organizations; six were members of…

  17. Twenty-Two Hispanic Leaders Discuss Poverty: Results from the Hispanic Leaders Study. Final Version.

    Science.gov (United States)

    Quiroz, Julia Teresa

    This study examines the perceptions of 22 national Hispanic American leaders about poverty among Hispanics. Eleven of the leaders were Mexican American; five were Puerto Rican; four were Cuban American; one was Central American; and one was South American. Twelve of the leaders were heads of public interest organizations; six were members of…

  18. Faunistic study of the aquatic beetles (Coleoptera: Polyphaga of Markazi Province (Central Iran with new records

    Directory of Open Access Journals (Sweden)

    Vafaei R.

    2007-01-01

    Full Text Available In this study, we establish the presence of 24 aquatic beetle (Coleoptera: Polyphaga species belonging to 13 genera and five families in Markazi Province of Central Iran. Specimens were collected between 2001 and 2005. Eleven species and four genera are recorded from Iran for the first time. The ecological significance of the new records is briefly discussed. .

  19. Determination of some individual chlorobiphenyls in eel-fat with capillary gaschromatography: collaborative study

    NARCIS (Netherlands)

    Tuinstra, L.G.M.T.; Roos, A.H.; Werdmuller, G.A.

    1984-01-01

    A method for the determination of six individual chlorobiphenyls in eel-fat, based on saponification of the sample and determination with capillary gas chromatography, was studied collaboratively. Eleven laboratories submitted analytical results in duplo of six individual chlorbiphenyls on two sampl

  20. Analytical and Numerical Study on the Uniformity of Temperature Difference Field in Heat Exchangers

    Institute of Scientific and Technical Information of China (English)

    Zhi-XinLi; Da-XiXiong; 等

    1995-01-01

    The relations of the uniformity factor of temperature difference field with the effctiveness of heat exchangers were studied analytically and numerically.The results for eleven kinds of heat exchangers show that the more uniform the temperature difference field,the higher the effctiveness of heat exchanger for a given Ntu and Cr.

  1. A longitudinal study of success and failure among scientist-started ventures

    NARCIS (Netherlands)

    Gurdon, M.A.; Samsom, K.J.

    2010-01-01

    We present the results from follow-up interviews in 2001 of scientists first studied in 1989 who had commercialized their inventions. Eleven of the original participating ventures had survived while six had failed outright. An effective combination of management team processes and access to capital

  2. Training Program for Emergency Medical Technician: Dispatcher. 3--Student Study Guide.

    Science.gov (United States)

    National Highway Traffic Safety Administration (DOT), Washington, DC.

    This study guide was developed to assist students enrolled in a training course for emergency medical technician (EMT) dispatchers. The guide includes unit objectives, key points, notes and questions related to the content, and review exercises for each of the eleven units included in the course. The course is divided into two parts. Part 1 covers…

  3. What Factors Affect Nursing Students' Decisions of Whether to Take Rural Jobs: An Exploratory Interview Study in China

    Science.gov (United States)

    Tao, Yuexian; Haycock-Stuart, Elaine; Rodgers, Sheila E.

    2016-01-01

    Purpose: The purpose of this study was to explore factors that effect nursing students' decisions of whether to take rural jobs in China. Methods: An exploratory interview study was conducted in China during May and June 2011. Eleven final year nursing students were purposively recruited from four nursing schools in one eastern area in China. The…

  4. Assessing E-Learning Tools in an Academic Environment: A Study of Availability and Use among Undergraduate Students in a Nigerian University

    Science.gov (United States)

    Ifijeh, Goodluck; Osinulu, Ifeakachuku; Esse, Ugwunwa; Adewole-Odeshi, Egbe; Fagbohun, Michael

    2015-01-01

    This study investigated the availability and use of e-learning tools as emerging paradigms in Covenant University, Nigeria. The study population comprise of 7000 undergraduate students, out of which 1000 was used as sample. Questionnaire was used as data collecting tool for the study. A total of five hundred and eleven questionnaires were filled…

  5. Probiotics for Antibiotic-Associated Diarrhoea (PAAD): a prospective observational study of antibiotic-associated diarrhoea (including Clostridium difficile-associated diarrhoea) in care homes.

    Science.gov (United States)

    Hood, Kerenza; Nuttall, Jacqui; Gillespie, David; Shepherd, Victoria; Wood, Fiona; Duncan, Donna; Stanton, Helen; Espinasse, Aude; Wootton, Mandy; Acharjya, Aruna; Allen, Stephen; Bayer, Antony; Carter, Ben; Cohen, David; Francis, Nick; Howe, Robin; Mantzourani, Efi; Thomas-Jones, Emma; Toghill, Alun; Butler, Christopher C

    2014-01-01

    BACKGROUND Antibiotic prescribing rates in care homes are higher than in the general population. Antibiotics disrupt the normal gut flora, sometimes causing antibiotic-associated diarrhoea (AAD). Clostridium difficile (Hall and O'Toole 1935) Prévot 1938 is the most commonly identified cause of AAD. Little is known either about the frequency or type of antibiotics prescribed in care homes or about the incidence and aetiology of AAD in this setting. OBJECTIVES The Probiotics for Antibiotic-Associated Diarrhoea (PAAD) study was designed as a two-stage study. PAAD stage 1 aimed to (1) prospectively describe antibiotic prescribing in care homes; (2) determine the incidence of C. difficile carriage and AAD (including C. difficile-associated diarrhoea); and (3) to consider implementation challenges and establish the basis for a sample size estimation for a randomised controlled trial (RCT) of probiotic administration with antibiotics to prevent AAD in care homes. If justified by PAAD stage 1, the RCT would be implemented in PAAD stage 2. However, as a result of new evidence regarding the clinical effectiveness of probiotics on the incidence of AAD, a decision was taken not to proceed with PAAD stage 2. DESIGN PAAD stage 1 was a prospective observational cohort study in care homes in South Wales with up to 12 months' follow-up for each resident. SETTING Recruited care homes had management and owner's agreement to participate and three or more staff willing to take responsibility for implementing the study. PARTICIPANTS Eleven care homes were recruited, but one withdrew before any residents were recruited. A total of 279 care home residents were recruited to the observational study and 19 withdrew, 16 (84%) because of moving to a non-participating care home. MAIN OUTCOME MEASURES The primary outcomes were the rate of antibiotic prescribing, incidence of AAD, defined as three or more loose stools (type 5-7 on the Bristol Stool Chart) in a 24-hour period, and C. difficile

  6. Sublethal effects of eleven insecticides of different categories on reproduction of Trichogrammatoidea bactrae Nagaraja (Hymenoptera:Trichogrammatidae )%11种不同类型杀虫剂对卷蛾分索赤眼蜂繁殖的亚致死效应

    Institute of Scientific and Technical Information of China (English)

    王德森; 潘飞; 何余容; 郭祥令; 陈俏

    2011-01-01

    The toxicity of eleven insecticides of different categories on adults of Trichogrammatoidea bactrae Nagaraja and the sublethal effects of insecticides on their reproduction under laboratory conditions were studied, so that the safety of insecticides to adults of T. bactrae was evaluated. The results showed that the adults of T. bactrae were the most susceptible to avermectins at 8 h after exposure to fresh, dry insecticide films in glass vials, the LC50 and sublethal concentration (LC30) values were O. 1984 mg/L and O. 1660 mg/L, respectively, and second susceptible to fipronii ( LC5o and LC3o values were O. 2027 mg/L and O. 1903 rog/L, respectively), chlorfenapyr ( LC50 and LC30 values were O. 3069 mg/L and O. 2038 rog/L,respectively), spinosad ( LC50 and LC30 values were 1. 3630 mg/L and 1. 0481 rog/L, respectively),cartap ( LC50 and LC30 values were 8. 1042 mg/L and 6. 7891 rag/L, respectively ), betacypermethrin ( LC50 and LC30 values were 10.3647 mg/L and 5. 8035 rog/L, respectively) and diafenthiuron ( LC50 and LC30 values were 11. 5318 mg/L and 9. 9212 mg/L, respectively). The LC30 values of avermectins,chlorfenapyr, cartap, diafenthiuron, spinosad and fipronil had significant effects on the longevity and fecundity of T. bactrae. After treated with these insecticides, the longevity of females ( 1.00 - 1.67 d) was shortened, and the number of eggs parasitized per female ( 0 - 21.70 ) decreased, and therefore the life table parameters (Ro, rm, λ and T) of T. bactrae were statistically lower than those in the control. The field recommended concentration of indoxacarb, chlorfluazuron, Bacillus thuringienesis and tebufenozide had no effect on the longevity and fecundity of T. bactrae, but after treated with these insecticides, the R0, rm and λ of T. bactrae were higher than those in the control. However, the longevity of females (3.77 d) was significantly extended, and the number of eggs parasitized per female (55.47) was significantly increased after the

  7. "Sharks in Your Hands"--A Case Study on Effects of Teaching Strategies to Change Knowledge and Attitudes towards Sharks

    Science.gov (United States)

    Lee, Hung-Shan; Liu, Shiang-Yao; Yeh, Ting-Kuang

    2016-01-01

    This study was designed to exemplify how hands-on based teaching strategies enhanced students' knowledge and positive attitudes towards sharks. Hands-on activities for sharks' biological and morphological features were carried out. Eleven elementary school students from a remote area in Taiwan were recruited and assigned to the hands-on condition.…

  8. The effect of moderate alcohol consumption on adiponectin oligomers and muscle oxidative capacity: A human intervention study

    NARCIS (Netherlands)

    Beulens, J.W.J.; Loon, L.J.C. van; Kok, F.J.; Pelsers, M.; Bobbert, T.; Spranger, J.; Helander, A.; Hendriks, H.F.J.

    2007-01-01

    Aims/hypothesis: The aim of this study was to investigate whether moderate alcohol consumption increases plasma high molecular weight (HMW) adiponectin and/or muscle oxidative capacity. Materials and methods: Eleven lean (BMI 18-25 kg/m2) and eight overweight (BMI ≥27 kg/m2) men consumed 100 ml

  9. The effect of moderate alcohol consumption on adiponectin oligomers and muscle oxidative capacity: a human intervention study

    NARCIS (Netherlands)

    Beulens, J.W.J.; Loon, van L.J.C.; Kok, F.J.; Pelsers, M.; Bobbert, T.; Spranger, J.; Helander, A.; Hendriks, H.F.J.

    2007-01-01

    Aims/hypothesis The aim of this study was to investigate whether moderate alcohol consumption increases plasma high molecular weight (HMW) adiponectin and/or muscle oxidative capacity. Materials and methods Eleven lean (BMI 18 - 25 kg/m(2)) and eight overweight ( BMI >= 27 kg/m(2)) men consumed

  10. The effect of moderate alcohol consumption on adiponectin oligomers and muscle oxidative capacity: A human intervention study

    NARCIS (Netherlands)

    Beulens, J.W.J.; Loon, L.J.C. van; Kok, F.J.; Pelsers, M.; Bobbert, T.; Spranger, J.; Helander, A.; Hendriks, H.F.J.

    2007-01-01

    Aims/hypothesis: The aim of this study was to investigate whether moderate alcohol consumption increases plasma high molecular weight (HMW) adiponectin and/or muscle oxidative capacity. Materials and methods: Eleven lean (BMI 18-25 kg/m2) and eight overweight (BMI ≥27 kg/m2) men consumed 100 ml whis

  11. The effect of moderate alcohol consumption on adiponectin oligomers and muscle oxidative capacity: a human intervention study

    NARCIS (Netherlands)

    Beulens, J.W.J.; Loon, van L.J.C.; Kok, F.J.; Pelsers, M.; Bobbert, T.; Spranger, J.; Helander, A.; Hendriks, H.F.J.

    2007-01-01

    Aims/hypothesis The aim of this study was to investigate whether moderate alcohol consumption increases plasma high molecular weight (HMW) adiponectin and/or muscle oxidative capacity. Materials and methods Eleven lean (BMI 18 - 25 kg/m(2)) and eight overweight ( BMI >= 27 kg/m(2)) men consumed 1

  12. Severe Traumatic Brain Injury, Frontal Lesions, and Social Aspects of Language Use: A Study of French-Speaking Adults

    Science.gov (United States)

    Dardier, Virginie; Bernicot, Josie; Delanoe, Anaig; Vanberten, Melanie; Fayada, Catherine; Chevignard, Mathilde; Delaye, Corinne; Laurent-Vannier, Anne; Dubois, Bruno

    2011-01-01

    The purpose of this study was to gain insight into the social (pragmatic) aspects of language use by French-speaking individuals with frontal lesions following a severe traumatic brain injury. Eleven participants with traumatic brain injury performed tasks in three areas of communication: production (interview situation), comprehension (direct…

  13. A Case Study of the Effects of the Gaskin Case on Seven School Districts in Southeastern Pennsylvania

    Science.gov (United States)

    Bell, Suzanne H.

    2010-01-01

    This qualitative study investigated the impact of the Gaskin v. Pennsylvania Department of Education Court Settlement Agreement on school districts in Southeast Pennsylvania. This class action suit was brought on behalf of students with physical, behavioral and developmental delays, their parents and eleven national organizations. The lawsuit…

  14. The Knee Clinical Assessment Study – CAS(K. A prospective study of knee pain and knee osteoarthritis in the general population: baseline recruitment and retention at 18 months

    Directory of Open Access Journals (Sweden)

    Duncan Rachel

    2006-03-01

    Full Text Available Abstract Background Selective non-participation at baseline (due to non-response and non-consent and loss to follow-up are important concerns for longitudinal observational research. We investigated these matters in the context of baseline recruitment and retention at 18 months of participants for a prospective observational cohort study of knee pain and knee osteoarthritis in the general population. Methods Participants were recruited to the Knee Clinical Assessment Study – CAS(K – by a multi-stage process involving response to two postal questionnaires, consent to further contact and medical record review (optional, and attendance at a research clinic. Follow-up at 18-months was by postal questionnaire. The characteristics of responders/consenters were described for each stage in the recruitment process to identify patterns of selective non-participation and loss to follow-up. The external validity of findings from the clinic attenders was tested by comparing the distribution of WOMAC scores and the association between physical function and obesity with the same parameters measured directly in the target population as whole. Results 3106 adults aged 50 years and over reporting knee pain in the previous 12 months were identified from the first baseline questionnaire. Of these, 819 consented to further contact, responded to the second questionnaire, and attended the research clinics. 776 were successfully followed up at 18 months. There was evidence of selective non-participation during recruitment (aged 80 years and over, lower socioeconomic group, currently in employment, experiencing anxiety or depression, brief episode of knee pain within the previous year. This did not cause significant bias in either the distribution of WOMAC scores or the association between physical function and obesity. Conclusion Despite recruiting a minority of the target population to the research clinics and some evidence of selective non-participation, this

  15. Determination of Eleven Components in Bushen Guchi Wan by LC-MS/MS Combined with Ion Switching Technology%补肾固齿丸中11种成分的LC-MS/MS-离子扫描切换法测定

    Institute of Scientific and Technical Information of China (English)

    张子建; 董立华; 孙冬晓; 郭盼盼; 王春英

    2013-01-01

    A LC-MS/MS method was established for the determination of eleven components in Bushen Guchi Wan. A C18 column was used with the mobile phase of methanol-water by gradient elution. Multiple reaction monitoring scanning mode was performed combined with the ion switching technology. Betaine, formononetin, schisandrin and 23-O-acetylalisol B were detected by positive ion scanning mode, while catalpol, sodium danshensu, salvianolic acid B, cinnamic acid, linarin, naringenin and paeonol were detected by negative ion scanning mode. All the compounds showed good linearity. Their recoveries were 98.5% - 107.0%, with RSDs of 0.7% -3.1%.%建立了液相色谱-串联质谱法同时测定补肾固齿丸中的11种成分.采用C18色谱柱,以甲醇-水为流动相,梯度洗脱.采用多反应离子检测,结合正负离子扫描切换,甜菜碱、芒柄花素、五味子醇甲和23-乙酰泽泻醇B采用正离子方式检测,梓醇、丹参素钠、丹酚酸B、肉桂酸、蒙花苷、柚皮素和丹皮酚采用负离子方式检测.所有被测物的线性关系良好;方法回收率为98.5%~107.0%,RSD为0.7%~3.1%.

  16. Functional, motor developmental, and long-term outcome after the component separation technique in children with giant omphalocele: A case control study

    NARCIS (Netherlands)

    Eijck, F.C. van; Vlimmeren, L.A. van; Wijnen, R.M.H.; Klein, W.; Kruijen, I.; Pillen, S.; Nijhuis-Van der Sanden, M.W.G.

    2013-01-01

    BACKGROUND/PURPOSE: The objective of this study was to evaluate the long-term functional and motor development and abdominal muscle quantity in children operated on for giant omphalocele (GOC) with the Component Separation Technique (CST). METHODS: Between 2004 and 2007, CST was applied in eleven co

  17. Branched chain enriched amino acid versus glucose treatment of hepatic encephalopathy. A double-blind study of 65 patients with cirrhosis

    DEFF Research Database (Denmark)

    Vilstrup, Hendrik; Gluud, C; Hardt, F

    1990-01-01

    ), or isocaloric glucose (33 patients) for a maximum of 16 days. The regimens further included glucose infusion to a total of 26.5 kcal/kg per day and lactulose. The patients took part in the study for 5-6 days. In each group 17 patients woke up. In the amino acid group eleven died and four developed renal failure...

  18. Effect of power-assisted hand-rim wheelchair propulsion on shoulder load in experienced wheelchair users : A pilot study with an instrumented wheelchair

    NARCIS (Netherlands)

    Kloosterman, Marieke G. M.; Buurke, Jaap H.; de Vries, Wiebe; Van der Woude, Lucas H. V.; Rietman, Johan S.

    2015-01-01

    This study aims to compare hand-rim and power-assisted hand-rim propulsion on potential risk factors for shoulder overuse injuries: intensity and repetition of shoulder loading and force generation in the extremes of shoulder motion. Eleven experienced hand-rim wheelchair users propelled an instrume

  19. Rotação de culturas: análise estatística de um experimento de longa duração em Campinas (SP Crop rotation: a statistical analysis of an eleven years experiment in Campinas, State of São Paulo, Brazil

    Directory of Open Access Journals (Sweden)

    Francisco Lombardi-Neto

    2002-08-01

    Full Text Available Com o objetivo de determinar o efeito da rotação no rendimento das culturas de algodão, amendoim, arroz, cana-de-açúcar e milho, instalou-se em Campinas, São Paulo, Brasil, um experimento avaliado durante 11 anos (1963/64 a 1974/75, seguido de análise do efeito residual dessa prática (1975/76, tomando, como indicador da fertilidade do solo, o rendimento de grãos de milho, semeado em todas as parcelas. No planejamento do experimento, em blocos casualizados com vinte tratamentos e quatro repetições, considerou-se que todos os tratamentos devem estar presentes em todos os anos, a fim de avaliar com eficiência e maior rapidez o efeito da rotação. Os resultados evidenciaram que as culturas contínuas, apenas com adubação mineral, levaram à redução significativa da produção no decorrer dos anos. Os tratamentos com calagem inicial e adubação mineral anual mantiveram a produtividade média, apesar das grandes oscilações anuais da produção. O efeito da rotação, quando praticada com calagem inicial e adubação mineral anual, levou a uma produtividade satisfatória ao longo dos anos, bem superior à do cultivo contínuo de cada uma das culturas, principalmente quando as culturas anuais não receberam a calagem inicial.With the goal of determining the crop rotation effects on cotton, peanut, rice, sugar cane and maize yields, a rotation experiment was established in Campinas, State of São Paulo, Brazil, for eleven years (1963/64 to 1974/75. The residual effect was determined by planting maize on all experimental plots in the following year (1975/76. The experimental design was randomized blocks with twenty treatments and four replications, spanning all treatments in all years in order to have an efficient and faster evaluation of the crop rotation effects. The results showed that the continuous cropping with mineral fertilizer applied annually led to a significant decrease of crop yield. However, when this continuous cropping

  20. Simultaneous determination of eleven preservatives in food by capillary column-gas chromatography after ultrasound-assisted dispersive liquid-liquid microextraction%超声分散液相微萃取-气相色谱法同时测定食品中11种防腐剂

    Institute of Scientific and Technical Information of China (English)

    杨金玲; 江阳; 薛勇; 孙成均

    2015-01-01

    目的:建立食品中11种防腐剂的超声分散液相微萃取-气相色谱法。方法样品经9∶1二氯甲烷‐乙酸乙酯超声分散液相微萃取,FFAP毛细管色谱柱分离、FID 检测器检测。结果方法线性范围为0.068~400μg/m l ,相关系数为0.9990~0.9999,回收率为84%~122%,相对标准偏差为3.11%~5.83%,方法检出限为0.026~0.23μg/m l。结论该法简便、高效、经济、环境友好,适于不同食品中11种防腐剂同时快速测定。%Objective To establish a method for simultaneous determination of eleven preservatives in foods by gas chromatography after ultrasound‐assisted dispersive liquid-liquid microextraction .Methods The target pre‐servatives in food samples were ultrasound‐assisted dispersive liquid-liquid microextracted ,and then they were separated with FFAP capillary column and detected with FID detector .Results Linear ranges of the method were between 0 .068 and 400μg/mL with correlation coefficients varying from 0 .9990 to 0 .9999 .Recoveries and rela‐tive standard deviations (RSDs)were in the range from 84% to 122% and from 3 .11% to 5 .83% ,respectively . The limitation of detection was in the range form 0 .026μg/ml to 0 .23μg/ml with enrichment factors ranging from 57 to 225 for all target compounds .Conclusion The method is simple ,efficient ,cheap ,eco‐friendly and is suitable for simultaneous determination of 11 preservatives in different foods .

  1. Less healthy, but more active: Opposing selection biases when recruiting older people to a physical activity study through primary care

    Directory of Open Access Journals (Sweden)

    Carey Iain M

    2008-05-01

    Full Text Available Abstract Background Physical activity studies in older people experience poor recruitment. We wished to assess the influence of activity levels and health status on recruitment to a physical activity study in older people. Methods Comparison of participants and non-participants to a physical activity study using accelerometers in patients aged ≥ 65 years registered with a UK primary care centre. Logistic regression was used to calculate odds ratios (OR of participants in the accelerometer study with various adjustments. Analyses were initially adjusted for age, sex and household clustering; the health variables were then adjusted for physical activity levels and vice versa to look for independent effects. Results 43%(240/560 participated in the physical activity study. Age had no effect but males were more likely to participate than females OR 1.4(1.1–1.8. 46% (76/164 of non-participants sent the questionnaire returned it. The 240 participants reported greater physical activity than the 76 non-participants on all measures, eg faster walking OR 3.2(1.4–7.7, or 10.4(3.2–33.3 after adjustment for health variables. Participants reported more health problems; this effect became statistically significant after controlling for physical activity, eg disability OR 2.4(1.1–5.1. Conclusion Physical activity studies on older primary care patients may experience both a strong bias towards participants being more active and a weaker bias towards participants having more health problems and therefore primary care contact. The latter bias could be advantageous for physical activity intervention studies, where those with health problems need targeting.

  2. MR imaging of the brain in large cohort studies: feasibility report of the population- and patient-based BiDirect study

    Energy Technology Data Exchange (ETDEWEB)

    Teuber, Anja; Berger, Klaus; Wersching, Heike [University of Muenster, Institute of Epidemiology and Social Medicine, Muenster (Germany); Sundermann, Benedikt; Kugel, Harald; Schwindt, Wolfram; Heindel, Walter [University Hospital Muenster, Department of Clinical Radiology, Muenster (Germany); Minnerup, Jens [University Hospital Muenster, Department of Neurology, Muenster (Germany); Dannlowski, Udo [University of Muenster, Department of Psychiatry, Muenster (Germany); University of Marburg, Department of Psychiatry, Marburg (Germany)

    2017-01-15

    To describe the implementation and protocol of cerebral magnetic resonance imaging (MRI) in the longitudinal BiDirect study and to report rates of study participation as well as management of incidental findings. Data came from the BiDirect study that investigates the relationship between depression and arteriosclerosis and comprises 2258 participants in three cohorts: 999 patients with depression, 347 patients with manifest cardiovascular disease (CVD) and 912 population-based controls. The study program includes MRI of the brain. Reasons for non-participation were systematically collected. Incidental findings were categorized and disclosed according to clinical relevance. At baseline 2176 participants were offered MRI, of whom 1453 (67 %) completed it. Reasons for non-participation differed according to cohort, age and gender with controls showing the highest participation rate of 79 %. Patient cohorts had higher refusal rates and CVD patients a high prevalence of contraindications. In the first follow-up examination 69 % of participating subjects completed MRI. Incidental findings were disclosed to 246 participants (17 %). The majority of incidental findings were extensive white matter hyperintensities requiring further diagnostic work-up. Knowledge about subjects and sensible definition of incidental findings are crucial for large-scale imaging projects. Our data offer practical and concrete information for the design of future studies. (orig.)

  3. [Evaluation, correction and impact of non-response in studies of childhood obesity].

    Science.gov (United States)

    Santiago-Pérez, María Isolina; Pérez-Ríos, Mónica; Malvar, Alberto; Suanzes, Jorge; Hervada, Xurxo

    2017-09-25

    To evaluate and correct the impact of non-response in the prevalence of underweight, overweight and obesity in children aged 6 to 15 years old using silhouette scales. Cross-sectional study carried out in 2013 among 8,145 Galician schoolchildren aged 6-15 years old. The students who agreed to participate were weighed and measured and, based on body mass index, the prevalence of underweight, overweight and obesity was estimated. Teachers rated all students using silhouette scales. The valuations were used to estimate the prevalence corrected by non-response. Using the Bayes theorem, participation rates were estimated according to weight status. The participation rate was 92.3% in the 6 -to 11-year-old group, and 90% in the 12- to 15-year old age group. In both groups, the prevalence of underweight and overweight were similar between participants and non-participants. However, obesity was higher among non-participants, especially at 12 to 15 years of age (6.3% vs. 12.2% ; p < 0.05). The prevalence did not change when corrected by the teacher's valuation. The participation rate of obese students was lower than the overall rate (82% vs. 90% at 12 to 15 years old; p < 0.05). The presence of participation bias, which was greater at 12-15 years old, was confirmed. However, the impact of the bias on prevalence was negligible due to the high participation rate. In obesity studies with objective measures, it is essential to quantify non-participation, as well as to assess its impact and correct it. Copyright © 2017 SESPAS. Publicado por Elsevier España, S.L.U. All rights reserved.

  4. Insensitivity to Scope in Contingent Valuation Studies

    DEFF Research Database (Denmark)

    Søgaard, Rikke; Lindholt, Jes Sanddal; Gyrd-Hansen, Dorte

    2012-01-01

    insensitivity and to assess the relevance of potential explanations that may help to shed light on how to appropriately handle this problem in contingent valuation studies. Methods: We surveyed a sample of 2004 men invited for cardiovascular disease screening. Each respondent had three contingent valuation...... tasks from which their sensitivity to larger risk reductions (test 1) and to change in travel costs associated with participation (test 2) could be assessed. Participants were surveyed while waiting for their screening session. Non-participants were surveyed by postal questionnaire. Results: The sample...... was overall found to be sensitive to scope, testing at the conventional sample-mean level. At the individual respondent level, however, more than half of the respondents failed the tests. Potential determinants for failing the tests were examined in alternative regression models but few consistent...

  5. Comparison of waist-to-hip ratio and other obesity indices as predictors of cardiovascular disease risk in people with type-2 diabetes: a prospective cohort study from ADVANCE.

    NARCIS (Netherlands)

    Czernichow, S.; Kengne, A.P.; Huxley, R.R.; Batty, G.D.; Galan, B.E. de; Grobbee, D.; Pillai, A.; Zoungas, S.; Marre, M.; Woodward, M.; Neal, B.; Chalmers, J.

    2011-01-01

    AIMS: The aim of this study was to compare the strength of associations and discrimination capability of body mass index (BMI), waist circumference (WC) and waist-to-hip ratio (WHR) with cardiovascular disease risk in individuals with type-2 diabetes. METHODS AND RESULTS: Eleven thousand, one hundre

  6. 巨型艾美耳球虫(Eimeria maxima)地理株研究Ⅰ.11株巨型艾美耳球虫的分离与基本特征%Study on Geographical Strains of Eimeria maxima Ⅰ.Isolation and biological characterization of eleven geographical strains of Eimeria maxima

    Institute of Scientific and Technical Information of China (English)

    陶建平; 辛玲; 李文超; 戴亚斌; 沈永林

    2004-01-01

    采用单卵囊分离技术,从江苏、安徽、山东、广东、福建和上海等省(市)10个地区的鸡场及美国的球虫病疫苗中获得了11株纯种球虫.根据下列特征:(1)卵囊的大小、形态和颜色;(2)孢子囊的大小和形态;(3)形状指数(卵囊长宽之比);(4)虫体肠道中的寄生区;(5)肉眼病变的性质;(6)最早孢子发育时间;(7)最短的潜在期,对这11株纯种球虫作了鉴定.结果表明,11株纯种球虫均为巨型艾关耳球虫(Eimeria maxima Tyzzer,1929)地理株.应用SPSS软件系统,对各株进行描述性统计和方差分析,结果显示,11株间存在不同程度的差异,而美国株与国内各株均有显著差异.

  7. Study

    Directory of Open Access Journals (Sweden)

    Susan Grandy

    2012-01-01

    Full Text Available Purpose. This study examined the association between self-reported weight change and quality of life, and exercise and weight management behaviors among individuals with type 2 diabetes mellitus (T2DM. Methods. In the US SHIELD study, respondents reported whether they had lost or gained weight compared with 1 year earlier and completed the SHIELD-WQ-9 quality of life questionnaire as well as provided information on their exercise and weight management behaviors in the past 12 months. Results. Sixteen percent of the respondents reported gaining weight (n=460, and 30% reported losing weight (n=895. More respondents who reported losing weight exercised regularly, limited calorie and fat intake, and increased fiber, fruit, and vegetable intake compared with respondents who reported gaining weight (P<0.01. For all nine aspects of daily life, a significantly greater proportion of respondents who reported losing weight reported improved well-being (12%–44% compared with respondents who reported gaining weight (P<0.0001. Conclusions. Self-reported weight loss was associated with improved well-being, better exercise, and weight management behaviors among individuals with T2DM.

  8. Why are poorer children at higher risk of obesity and overweight? A UK cohort study

    OpenAIRE

    Goisis, A.; Sacker, A; Kelly, Y.

    2015-01-01

    BACKGROUND: There is limited evidence on which risk factors attenuate income inequalities in child overweight and obesity; whether and why these inequalities widen as children age. METHOD: Eleven thousand nine hundred and sixty five singletons had complete data at age 5 and 9384 at age 11 from the Millennium Cohort Study (UK). Overweight (age 5 : 15%; age 11 : 20%) and obesity (age 5 : 5%; age 11 : 6%) were defined using the International Obesity Taskforce body mass index cut-points. To measu...

  9. Study

    Directory of Open Access Journals (Sweden)

    Erum Zahir

    2017-05-01

    Full Text Available Physicochemical properties like density, viscosity, boiling point, saponification value (SV, iodine value (IV,and peroxide value (PV of Corn and Mustard oils were studied to evaluate the compositional quality of oils and also to investigate the effect on the use of same oil for repeated frying as it ultimately changes the physicochemical, nutritional and sensory properties of the oil. FT-IR spectroscopy was used to evaluate the degree of oxidation after heating and frying processes. Results revealed that due to the temperature change in the oil there is a notable difference in the spectral band which showed that the proportions of the fatty acids were changed. The spectra of Corn oil at the boiling point and at multiple frying times with a piece of potato showed frequencies in range of 2852.7–2926.0 cm−1 while in Mustard oil an additional peak was observed at 3633.8 cm−1 which exhibits the secondary oxidized product formation.

  10. Relatives in older patients' fast-track treatment programme during total hip or knee replacement. A grounded theory study

    DEFF Research Database (Denmark)

    Berthelsen, Connie Bøttcher

    was collected between 2010 and 2011 in the orthopaedic wards of two Copenhagen university hospitals, and guided by theoretical sampling. Study I: Seven relatives of patients over 70 years of age participated. Data consisted of 14 non-participant observations, 14 post-observational interviews, and five formal...... interviews. Maintaining Unity emerged as the relatives’ pattern of behaviour, through which they resolved their main concern; preventing the patients from feeling alone. The relatives resolved their main concern through three interchangeable behavioural modes: Protecting mode, by providing loving...

  11. Multi-Band Feeds: A Design Study

    CERN Document Server

    Maan, Yogesh; Raja, Wasim; Mehta, Nikhil

    2012-01-01

    Broadband antenna feeds are of particular interest to existing and future radio telescopes for multi-frequency studies of astronomical sources. Although a 1:15 range in frequency is difficult to achieve, the well-known Eleven feed design offers a relatively uniform response over such a range, and reasonably well-matched responses in E & H planes. However, given the severe Radio Frequency Interference in several bands over such wide spectral range, one desires to selectively reject the corresponding bands. With this view, we have explored the possibilities of having a multi-band feed antenna spanning a wide frequency range, but which would have good response only in a number of pre-selected (relatively) RFI-free windows (for a particular telescope-site). The designs we have investigated use the basic configuration of pairs of dipoles as in the Eleven feed, but use simple wire dipoles instead of folded dipoles used in the latter. From our study of the two designs we have investigated, we find that the desig...

  12. INTER-LABORATORY VALIDATION STUDY OF THE SKIN^2 DERMAL MODEL ZK1100 AND MTT CYTOTOXICITY ASSAY KITS

    OpenAIRE

    1994-01-01

    An inter-laboratory validation study was conducted to evaluate the potential of 4 chemicals to cause irritation with utilizing the Skin^2 Dermal Model ZK1100 kit developed by Advanced Tissue Sciences, Inc. (formerly Marrow-Tech, Inc., La Jolla, California, USA). The chemicals tested were sodium dodecyl sulfate (SDS), 1-n-hexadecyl-pyridinium chloride monohydrate (CC), ethanol (EtOH), and dimethyl sulfoxide (DMSO). Eleven Japanese insititutions participated in this validation research to evalu...

  13. Mental health and social participation skills of wheelchair basketball players: a controlled study.

    Science.gov (United States)

    Fiorilli, Giovanni; Iuliano, Enzo; Aquino, Giovanna; Battaglia, Claudia; Giombini, Arrigo; Calcagno, Giuseppe; di Cagno, Alessandra

    2013-11-01

    The aim of this study was to assess differences in psychological well-being, symptomatic psychological disorders and social participation, between competitive wheelchair basketball participants and those non-participants. Forty-six wheelchair participants, 24 Basketball players (aged 35.60 ± 7.56) and 22 non-players (aged 36.20 ± 6.23), completed three validated self-report questionnaires: Participation Scale (PS), Psychological Well-Being Scale [PWBS] and Symptom Checklist 90 R [SCL-90-R]. ANOVA showed significant overall differences between the two groups. The social restriction score, evaluated by PS, was significantly higher in the non-basketball participants (p=0.00001) than the basketball participants. The PWB Scale showed significant differences in all 6 dimensions: positive relations with others, environmental mastery, personal growth, purpose in life and self-acceptance (pbasketball participants. The SCL-90-R scores were significantly lower for the basketball group in the following 6 symptomatic dimensions: depression, phobic anxiety, and sleep disorder (pbasketball participants showed better psychological well-being and social skills than those non-participants.

  14. Study protocol of the CHOiCE trial

    DEFF Research Database (Denmark)

    Nielsen, Mette Tranberg; Bech, Bodil Hammer; Blaakær, Jan;

    2016-01-01

    BACKGROUND: The effectiveness of cervical cancer screening programs is challenged by suboptimal participation and coverage. Offering cervico-vaginal self-sampling for human papillomavirus testing (HPV self-sampling) to non-participants can increase screening participation. However, the effect......-up testing at 30, 60, or 90 days after mail out of the results. DISCUSSION: The CHOiCE trial will provide strong and important evidence allowing us to determine if and how HPV self-sampling can be used to increase participation in cervical cancer screening. This trial therefore has the potential to improve...... varies substantially among studies, especially depending on the approach used to offer HPV self-sampling. The present trial evaluates the effect on participation in an organized screening program of a HPV self-sampling kit mailed directly to the home of the woman or mailed to the woman's home on demand...

  15. On the Non-participation in Public Decision%试论公共决策中的公众不参与

    Institute of Scientific and Technical Information of China (English)

    彭明春

    2004-01-01

    公众参与公共决策过程有利于减少决策失误,实现决策的科学化、民主化.然而由于体制、参与渠道、参与热情和效能感以及对参与的成本、收益预期等方面的原因,往往导致公众不参与.必须采取措施,减少和避免公众的不参与.

  16. Toepasbaarheid en effectiviteit van mindfulnesstraining bij volwassenen met AD(H)D; een open pilotonderzoek [Feasibility and effectiveness of mindfulness training in adults with ADHD: A pilot study

    OpenAIRE

    Hepark, S.; Kan, C C; Speckens, A.E.M.

    2014-01-01

    BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is a developmental disorder that often continues into adulthood. Stimulant medication is the common treatment for ADHD. However, there is a need for psychosocial interventions in addition to medication. AIM: To conduct a pilot study which examines the feasibility and effectiveness of mindfulness training for adults with ADHD. METHOD: Eleven adults with ADHD participated in a mindfulness training scheme lasting 10 weeks. ADHD symptoms...

  17. Stereotypes of English in Hollywood Movies : A Case Study of the Use of Different Varieties of English in Star Wars, The Lord of the Rings and Transformers.

    OpenAIRE

    Andersson, Niklas

    2010-01-01

    This essay deals with the use of linguistic stereotypes in Hollywood movies. It investigates whether attitudes towards English dialects found in studies on perceptual dialectology are reflected in the selected movies and discusses the notion of linguistic identity and how standard and nonstandard speech, respectively, are used symbolically to emphasize features of characters in eleven movies from three different movie series, namely The Lord of the Rings, Star Wars and Transformers, with a ma...

  18. Reducing economic disparities between rural and urban areas through integrated development – Case study: analysis of the turnover of companies in the AIDA Association, Alba County, Romania

    OpenAIRE

    Ionela Gavrilă-Paven; Emil Olteanu; Iulian Bogdan Dobra

    2014-01-01

    This paper presents a local initiative in Romania, Alba County, which tries to establish general guidelines for the sustainable development of a local community that consists of three towns and eight villages. The analysis conducted in this paper is focused on economic activity. The turnover of the companies located in the eleven localities that compose the Intercommunity Development Association – Alba Iulia have been studied. The authors’ objective is to determine the influenc...

  19. Action-Oriented Study Circles Facilitate Efforts in Nursing Homes to “Go from Feeding to Serving”: Conceptual Perspectives on Knowledge Translation and Workplace Learning

    Directory of Open Access Journals (Sweden)

    Albert Westergren

    2012-01-01

    Full Text Available Background. Action-oriented study circles (AOSC have been found to improve nutrition in 24 nursing homes in Sweden. Little, however, is known about the conceptual use of knowledge (changes in staffs’ knowledge and behaviours. Methods. Qualitative and quantitative methods, structured questionnaires for evaluating participants’ (working in nursing homes experiences from study circles (n=592, 71 AOSC and for comparisons between AOSC participants (n=74 and nonparticipants (n=115. Finally, a focus group interview was conducted with AOSC participants (in total n=12. Statistical, conventional, and directed content analyses were used. Results. Participants experienced a statistically significant increase in their knowledge about eating and nutrition, when retrospectively comparing before participating and after, as well as in comparison to non-participants, and they felt that the management was engaged in and took care of ideas regarding food and mealtimes to a significantly greater extent than non-participants. The use of AOSC was successful judging from how staff members had changed their attitudes and behaviours toward feeding residents. Conclusions. AOSC facilitates professional development, better system performance, and, as shown in previous studies, better patient outcome. Based on a collaborative learning perspective, AOSC manages to integrate evidence, context, and facilitation in the efforts to achieve knowledge translation in a learning organisation. This study has implications also for other care settings implementing AOSC.

  20. Pilot study of a heptavalent vaccine-keyhole limpet hemocyanin conjugate plus QS21 in patients with epithelial ovarian, fallopian tube, or peritoneal cancer

    DEFF Research Database (Denmark)

    Sabbatini, Paul J; Ragupathi, Govind; Hood, Chandra

    2007-01-01

    PURPOSE: To characterize the safety and immunogenicity of a heptavalent antigen-keyhole limpet hemocyanin (KLH) plus QS21 vaccine construct in patients with epithelial ovarian, fallopian tube, or peritoneal cancer in second or greater complete clinical remission. EXPERIMENTAL DESIGN: Eleven......). RESULTS: Eleven patients were included in the safety analysis; 9 of 11 patients remained on study for at least 2 weeks past fourth vaccination and were included in the immunologic analysis (two withdrew, disease progression). The vaccine was well tolerated. Self-limited and mild fatigue (maximum grade 2...... in seven of nine patients, with some increase seen in all patients. CONCLUSIONS: This heptavalent-KLH conjugate plus QS21 vaccine safely induced antibody responses against five of seven antigens. Investigation in an adequately powered efficacy trial is warranted....

  1. Studying Executive Barriers on Rationalizing the Size of Iranian Government

    Directory of Open Access Journals (Sweden)

    Mohammad Hussein Rahmati

    2012-01-01

    Full Text Available To rationalize the size of government, Act on adjusting a part of government‟s financial rules is approved and the government is obliged to assign a part of its activities through (1 services by nonpublic sector, (2 partnership with nonpublic sector, and (3 assigning the management to nonpublic sector. There are many barriers in executing this law. The present study derived from a field study tries to provide a report on the performance of various organs in Qom province on executing this law and identifies the executive barriers and provides practical proposals to remove them.Overall, seventeen organs in Qom are subjected to this law of which five organs are selected as our sample. In this respect, different documents were studied, ten interviews were conducted and one hundred and four executive barriers and forty seven operational proposals including twenty three barriers and eleven proposals in organization and structure area, sixteen barriers and five proposals in administrative technology and working processes area, thirty two barriers and twelve proposals in human resources area, twenty one barriers and eight proposals in laws and regulations area and twelve barriers and eleven proposals in management area have been analyzed and summarized regarding their contents.

  2. MR imaging of the brain in large cohort studies: feasibility report of the population- and patient-based BiDirect study.

    Science.gov (United States)

    Teuber, Anja; Sundermann, Benedikt; Kugel, Harald; Schwindt, Wolfram; Heindel, Walter; Minnerup, Jens; Dannlowski, Udo; Berger, Klaus; Wersching, Heike

    2017-01-01

    To describe the implementation and protocol of cerebral magnetic resonance imaging (MRI) in the longitudinal BiDirect study and to report rates of study participation as well as management of incidental findings. Data came from the BiDirect study that investigates the relationship between depression and arteriosclerosis and comprises 2258 participants in three cohorts: 999 patients with depression, 347 patients with manifest cardiovascular disease (CVD) and 912 population-based controls. The study program includes MRI of the brain. Reasons for non-participation were systematically collected. Incidental findings were categorized and disclosed according to clinical relevance. At baseline 2176 participants were offered MRI, of whom 1453 (67 %) completed it. Reasons for non-participation differed according to cohort, age and gender with controls showing the highest participation rate of 79 %. Patient cohorts had higher refusal rates and CVD patients a high prevalence of contraindications. In the first follow-up examination 69 % of participating subjects completed MRI. Incidental findings were disclosed to 246 participants (17 %). The majority of incidental findings were extensive white matter hyperintensities requiring further diagnostic work-up. Knowledge about subjects and sensible definition of incidental findings are crucial for large-scale imaging projects. Our data offer practical and concrete information for the design of future studies. • Willingness to participate in MRI is generally high, also in follow-up examinations. • Rates of refusal and prevalence of contraindications differ according to subject characteristics. • Extensive white matter hyperintensities considerably increase the disclosure rates of incidental findings. • MRI workflow requires continuous case-by-case handling by an interdisciplinary team.

  3. [Key technologies elements of clinical study of traditional Chinese medicine new drugs on children's dermatitis and eczema].

    Science.gov (United States)

    Zhong, Cheng-Liang; Zhang, Chun; Hu, Si-Yuan

    2013-06-01

    We assessed and graded the evidence of relevant systematic reviews and randomized controlled trials, combined with our clinical study practice to identify eleven key elements as a focus for the clinical study of traditional Chinese medicine (TCM) new drugs on children's dermatitis and eczema: the primary purpose and design of the study, the inclusion and exclusion criteria of the study, the treatment, the trail procedure,the effectiveness and safety evaluation, and quality control, etc, as well. In addition, seven recommendations for the design of clinical study of TCM new drugs on children's dermatitis and eczema were provided.

  4. New insight into the molecular basis of 3beta-hydroxysteroid dehydrogenase deficiency: identification of eight mutations in the HSD3B2 gene eleven patients from seven new families and comparison of the functional properties of twenty-five mutant enzymes.

    Science.gov (United States)

    Moisan, A M; Ricketts, M L; Tardy, V; Desrochers, M; Mébarki, F; Chaussain, J L; Cabrol, S; Raux-Demay, M C; Forest, M G; Sippell, W G; Peter, M; Morel, Y; Simard, J

    1999-12-01

    Classical 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase (3betaHSD) deficiency is a form of congenital adrenal hyperplasia that impairs steroidogenesis in both the adrenals and gonads resulting from mutations in the HSD3B2 gene and causing various degrees of salt-wasting in both sexes and incomplete masculinization of the external genitalia in genetic males. To identify the molecular lesion(s) in the HSD3B2 gene in the 11 patients from the seven new families suffering from classical 3betaHSD deficiency, the complete nucleotide sequence of the whole coding region and exon-intron splicing boundaries of this gene was determined by direct sequencing. Five of these families were referred to Morel's molecular diagnostics laboratory in France, whereas the two other families were investigated by Peter's group in Germany. Functional characterization studies were performed by Simard's group in Canada. Following transient expression in 293 cells of each of the mutant recombinant proteins generated by site-directed mutagenesis, the effect of the 25 mutations on enzyme activity was assessed by incubating intact cells in culture with 10 nM [14C]-DHEA as substrate. The stability of the mutant proteins has been investigated using a combination of Northern and Western blot analyses, as well as an in vitro transcription/translation assay using rabbit reticulocyte lysates. The present report describes the identification of 8 mutations, in seven new families with individuals suffering from classical 3betaHSD deficiency, thus increasing the number of known HSD3B2 mutations involved in this autosomal recessive disorder to 31 (1 splicing, 1 in-frame deletion, 3 nonsense, 4 frameshift and 22 missense mutations). In addition to the mutations reported here in these new families, we have also investigated for the first time the functional significance of previously reported missense mutations and or sequence variants namely, A82T, A167V, L173R, L205P, S213G and K216E, P222H, T259

  5. ICPP tank farm closure study. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Spaulding, B.C.; Gavalya, R.A.; Dahlmeir, M.M. [and others

    1998-02-01

    The disposition of INEEL radioactive wastes is now under a Settlement Agreement between the DOE and the State of Idaho. The Settlement Agreement requires that existing liquid sodium bearing waste (SBW), and other liquid waste inventories be treated by December 31, 2012. This agreement also requires that all HLW, including calcined waste, be disposed or made road ready to ship from the INEEL by 2035. Sodium bearing waste (SBW) is produced from decontamination operations and HLW from reprocessing of SNF. SBW and HLW are radioactive and hazardous mixed waste; the radioactive constituents are regulated by DOE and the hazardous constituents are regulated by the Resource Conservation and Recovery Act (RCRA). Calcined waste, a dry granular material, is produced in the New Waste Calcining Facility (NWCF). Two primary waste tank storage locations exist at the ICPP: Tank Farm Facility (TFF) and the Calcined Solids Storage Facility (CSSF). The TFF has the following underground storage tanks: four 18,400-gallon tanks (WM 100-102, WL 101); four 30,000-gallon tanks (WM 103-106); and eleven 300,000+ gallon tanks. This includes nine 300,000-gallon tanks (WM 182-190) and two 318,000 gallon tanks (WM 180-181). This study analyzes the closure and subsequent use of the eleven 300,000+ gallon tanks. The 18,400 and 30,000-gallon tanks were not included in the work scope and will be closed as a separate activity. This study was conducted to support the HLW Environmental Impact Statement (EIS) waste separations options and addresses closure of the 300,000-gallon liquid waste storage tanks and subsequent tank void uses. A figure provides a diagram estimating how the TFF could be used as part of the separations options. Other possible TFF uses are also discussed in this study.

  6. Comparação do código de ética médica do Brasil e de 11 países Comparison of the code of medical ethics of Brazil with those of eleven countries

    Directory of Open Access Journals (Sweden)

    Jayme Augusto Rocha Vianna

    2006-12-01

    their objectives. METHODS: Codes from five continents and 11 countries: Argentina, Chile, Canada, United States, Portugal, United Kingdom, South Africa, Egypt, China, India, and Australia were studied. Information was obtained from the Internet, by accessing sites of regulatory agencies and medical associations. Codes were described and compared according to information about the setting-up organization, spatial scope, compulsory extent, date of enforcement, organizational rules and auxiliary documents. RESULTS: The codes of ethics studied were: 59% created by the medical regulatory agency of the country, 92% of national scope, 67% compulsive for all physicians and 73% were last updated after the year 2000. A relation between the setting-up organization and the compulsory extent and spatial scope of the codes was observed. Need for systematic updating of the codes was noted. Updating is often carried out through auxiliary documents, however, there may be difficulties in making these contents known. The possibility of organizing the guidelines by topics, each followed by a small text was considered. CONCLUSION: This study presented suggestions for the Code of Medical Ethics of Brazil: conduct a review and an update of the code, organize the guidelines, including explanations and justifications, separate the ethical resolutions and finally improve its divulgation.

  7. Genome-wide association study identifies single-nucleotide polymorphism in KCNB1 associated with left ventricular mass in humans: The HyperGEN Study

    Directory of Open Access Journals (Sweden)

    Kraemer Rachel

    2009-05-01

    Full Text Available Abstract Background We conducted a genome-wide association study (GWAS and validation study for left ventricular (LV mass in the Family Blood Pressure Program – HyperGEN population. LV mass is a sensitive predictor of cardiovascular mortality and morbidity in all genders, races, and ages. Polymorphisms of candidate genes in diverse pathways have been associated with LV mass. However, subsequent studies have often failed to replicate these associations. Genome-wide association studies have unprecedented power to identify potential genes with modest effects on left LV mass. We describe here a GWAS for LV mass in Caucasians using the Affymetrix GeneChip Human Mapping 100 k Set. Cases (N = 101 and controls (N = 101 were selected from extreme tails of the LV mass index distribution from 906 individuals in the HyperGEN study. Eleven of 12 promising (Q Results Despite the relatively small sample, we identified 12 promising SNPs in the GWAS. Eleven SNPs were successfully genotyped in the validation study of 704 Caucasians and 1467 African Americans; 5 SNPs on chromosomes 5, 12, and 20 were significantly (P ≤ 0.05 associated with LV mass after correction for multiple testing. One SNP (rs756529 is intragenic within KCNB1, which is dephosphorylated by calcineurin, a previously reported candidate gene for LV hypertrophy within this population. Conclusion These findings suggest KCNB1 may be involved in the development of LV hypertrophy in humans.

  8. 防风挥发油的气相色谱指纹图谱研究%Study on GC Fingerprint of Essential Oil from Radix Saposhnikoviae

    Institute of Scientific and Technical Information of China (English)

    戴静波; 张雅娟; 周俊慧

    2013-01-01

    目的 建立防风挥发油指纹图谱的研究方法.方法 用水蒸气蒸馏法提取,采用程序升温对11 批防风油的气相色谱进行分析,并采用气相色谱-质谱联用技术鉴定其指纹特征峰,并用聚类分析法比较.结果 11 批防风饮片的挥发油相似度较高.结论 本方法准确可靠,较为简便,所建立的指纹图谱特征明显,可作为防风药材的质量控制方法之一.%Objective To study and establish the GC fingerprint of essential oil from Radix Saposhnikoviae. Methods Eleven batches of essential oils were extracted by steam distillation, then separated by capillary gas chromatography. GC of the essential oil in eleven batches of Radix Saposhnikoviae was analyzed by adopting temperature programmer, the fingerprint peaks were identified by GC-MS method and compared by cluster analysis. Results The similarity of eleven batches of Radix Saposhnikoviae was high. Conclusion The method is simple, precise and reliable. The established fingerprints can be used as one of the quality control index for Radix Saposhnikoviae.

  9. 中国11城市医院老年科就诊良性前列腺增生患者患病情况及相关因素分析%The investigation of benign prostatic hyperplasia and its related factors in geriatrics department of eleven cities in China

    Institute of Scientific and Technical Information of China (English)

    吴楠; 于普林; 王建业; 虞龙; 张传芳; 杨静; 孙振球

    2009-01-01

    Objective To study the present situation of benign prostatic hyperplasia (BPH) of male patients in geriatrics department. Methods Two thousand one hundred and twenty-five patients aged 60 years and above with BPH in geriatrics department of Chengdu, Lanzhou, Hangzhou, Wuhan, Changsha, Guangzhou, Shenyang, Shanghai, Nanjing, Jinan and Beijing were investigated using stratified cluster random sampling method. Results The constituent ratio of patients with benign prostatic hyperplasia in geriatrics department was 47.0%, and the proportions of the elderly of 60~,70~ ,80~ years old among the patients with benign prostatic hyperplasia were 18.1%,49.4 and 32.5%, respectively (x2 = 83.68, P<0.001). There was a significant difference in the occupation distribution of BPH constituent ratio: 66.4% for staffs of state organs, 18.0% for professional technical personnel and 14.7% for works and peasants (x2=410.27,P<0.001). The international prostate symptom scores (IPSS) were different among different cities (x2=101.00, P<0. 001 ). Logistic regression analysis showed that the IPSS was correlated with age and profession (age: OR= 1.029;worker and peasant as control group, working staff of state organs OR=O.707, professional technical personnel OR=0.339 ). Conclusions The benign prostatic hyperplasia is a common disease in male elderly patients in China, but the consultation rate is low. The IPSS of benign prostatic hyperplasia is correlated with age and profession. Prevention and treatment of benign prostatic hyperplasia in the elderly should be strengthened.%目的 调查就诊于老年科的老年人中良性前列腺增生(BPH)患者的患病情况.方法 采用分层整群随机抽样的方法,对11个城市医院老年科2125例60岁及以上的就诊老年人进行横断而流行病学调查.结果 BPH占就诊疾病的构成比为47.0%,BPH患者按年龄分组60~、70~、80~岁的构成比分别为18.1%、49.4%、32.5%,BPH患者各年龄组构成

  10. Advanced Clothing Studies

    Science.gov (United States)

    Orndoff, Evelyne; Poritz, Darwin

    2014-01-01

    All human space missions require significant logistical mass and volume that add an unprecedented burden on longduration missions beyond low-Earth orbit. For these missions with limited cleaning resources, a new wardrobe must be developed to reduce this logistical burden by reducing clothing mass and extending clothing wear. The present studies have been undertaken, for the first time, to measure length of wear and to assess the acceptance of such extended wear. Garments in these studies are commercially available exercise T-shirts and shorts, routine-wear T-shirts, and longsleeved pullover shirts. Fabric composition (cotton, polyester, light-weight, superfine Merino wool, modacrylic, cotton/rayon, polyester/Cocona, modacrylic/Xstatic, modacrylic/rayon, modacrylic/lyocell/aramid), construction (open knit, tight knit, open weave, tight weave), and finishing treatment (none, quaternary ammonium salt) are the independent variables. Eleven studies are reported here: five studies of exercise T-shirts, three of exercise shorts, two of routine wear Tshirts, and one of shirts used as sleep-wear. All studies are conducted in a climate-controlled environment, similar to a space vehicle's. For exercise clothing, study participants wear the garments during aerobic exercise. For routine wear clothing, study participants wear the T-shirts daily in an office or laboratory. Daily questionnaires collected data on ordinal preferences of nine sensory elements and on reason for retiring a used garment. Study 1 compares knitted cotton, polyester, and Merino exercise T-shirts (61 participants), study 2, knitted polyester, modacrylic, and polyester/Cocona exercise T-shirts (40 participants), study 3, cotton and polyester exercise shorts, knitted and woven (70 participants), all three using factorial experimental designs with and without a finishing treatment, conducted at the Johnson Space Center, sharing study participants. Study 4 compares knitted polyester and ZQ Merino exercise T

  11. 重庆11所高校大学生性与生殖健康问题及教育现状%On Present Situation of Sex and Reproductive Health and Education among Students from Eleven Universities in Chongqing

    Institute of Scientific and Technical Information of China (English)

    张爽; 纪娟; 刘关羽; 蒋长兰; 李秋玲; 丁裕斌; 付利娟

    2014-01-01

    The study aims to finding out the problems of sex and reproductive health education in the uni-versities in Chongqing by investigating the sex and reproductive health knowledge ,attitude and behavior of university students before exploring their demands on reproductive health education .Anonymous question-naire survey has been performed among 4023 students selected from 11 universities in Chongqing by strati-fied sampling .Only a few students correctly answered four questions about sex and reproductive health , such as the methods of emergency contraception .As to sex attitude ,boys are more open than girls .There are no significant differences of sex attitude between boys in different professions .However ,girls in art and physical class are more open than those in other professions .The incidence of sexual behavior in boys is higher than that in girls .Most college students surveyed are facing reproductive health problems ,and male college students concerned about premature ejaculation and impotence (29 .15% ) most ,w hile more female college students worried about the problems of irregular menstruation and dysmenorrhea (52 .54% ) .The students facing reproductive health problems usually apply network media for help .There are not enough school education of reproductive health within universities ,for 64 .3% of all surveyed col-lege students have no or just little access to reproductive health education w hile only 1 .05% are satisfied with the status of university reproductive health education .Universities should strengthen sex and repro-ductive health education ,focusing on targeted education to university students .%目的:了解重庆不同属性高校大学生对性知识知晓情况及性态度和性行为发生情况,学校生殖健康教育的现状,探讨学校性与生殖健康教育存在的问题.方法:采用分层抽样的方法抽取重庆市11所高校的大学生4023人后进行问卷调查,问卷有效性为82.6%.结果:性

  12. Contribution to the study of characteristics of Pelargonium resistance to an atmospheric pollutant, sulfur dioxide

    Energy Technology Data Exchange (ETDEWEB)

    Bonte, J.; Bonte, C.; de Cormis, L.; Louguet, P.

    1977-01-01

    Eleven varieties of Pelargonium, subjected simultaneously to similar conditions of sulfur dioxide pollution, are arranged in ascending order of sensitivity. There is no relation between the relative susceptibility of the varieties to SO/sub 2/, the stomatal frequency and the dimensions of the stomatal apparatus. Nevertheless, a statistical comparative study of the stomatal movements of 2 Pelargonium, one resistant, the other sensitive, has shown that the closing rate of stomata and the reduction percentage of stomatal diffusive capacity are significantly different. These characteristics might be taken into consideration in the selection of varieties resistant to atmospheric pollution.

  13. The effect of reminders in a web-based intervention study

    DEFF Research Database (Denmark)

    Svensson, M.; Svensson, T.; Hansen, A. W.;

    2012-01-01

    was sent. To encourage study participation, 4-5 and 11 e-mail reminders were sent at baseline and follow-up, respectively. Additional reminders (media articles, flyers, SMS etc) were also administered. Reminders (e-mails + additional) were given in low (a parts per thousand currency sign6 reminders......). About 29 % responded before any e-mail reminder, following 26 and 45 % after 1 respective a parts per thousand yen 2 e-mail reminders. Participant characteristics were not related to when the participants responded. The 4-5 e-mail reminders increased total response rate by 15 %, the eleven by 21...

  14. New developments of the ZZ Ceti instability strip: The discovery of eleven new variables

    CERN Document Server

    Castanheira, B G; Kleinman, S J; Nitta, A; Fraga, L; 10.1111/j.1365-2966.2010.16633.x

    2010-01-01

    Using the SOAR 4.1 m telescope, we report on the discovery of low amplitude pulsations for three stars previously reported as Not-Observed-to-Vary (NOV) by Mukadam et al. (2004) and Mullally et al. (2005), which are inside the ZZ Ceti instability strip. With the two pulsators discovered by Castanheira et al. (2007), we have now found variability in a total of five stars previously reported as NOVs. We also report the variability of eight new pulsating stars, not previously observed, bringing the total number of known ZZ Ceti stars to 148. In addition, we lowered the detection limit for ten NOVs located near the edges of the ZZ Ceti instability strip. Our results are consistent with a pure mass dependent ZZ Ceti instability strip.

  15. Oropharyngeal histoplasmosis: report of eleven cases and review of the literature

    Directory of Open Access Journals (Sweden)

    Vicente Sperb Antonello

    2011-02-01

    Full Text Available INTRODUCTION: Histoplasmosis is a systemic mycosis endemic in Brazil, especially in the State of Rio Grande do Sul, where Histoplasma capsulatum was isolated from the soil. H. capsulatum may compromise unusual areas, including the oropharynx, particularly in patients presenting disseminated histoplasmosis; which is associated with a state of immunosuppression, such as AIDS. METHODS: During database analysis of a total of 265 cases of histoplasmosis, the medical records of 11 patients with histological or microbiological diagnoses of oral histoplasmosis (OH between 1987 and 2008 were retrospectively reviewed. RESULTS: This work reports 11 cases of OH, the majority presenting histopathological or microbiological evidence of disseminated histoplasmosis (DH. In the patients with DH, OH was the first manifestation of histoplasmosis. Five of the 11 patients discussed were HIV-seropositive with clinical and laboratory findings of AIDS. Four patients presented active pulmonary tuberculosis concomitant with histoplasmosis. Treatment was based on the use of itraconazole and amphotericin B deoxycholate. Eight patients responded successfully to therapy after one year, two did not come back for reevaluation and one died despite adequate therapy. CONCLUSIONS: Oral histoplasmosis is closely associated with immunosuppression status, especially in patients presenting AIDS; moreover, in many cases, OH is the first sign of disseminated histoplasmosis.

  16. A Rare Cause of Macroscopic Hematuria on Eleven-Year-Old Girl: Bladder Hemangioma

    Directory of Open Access Journals (Sweden)

    Sezgin Guvel

    2013-06-01

    Full Text Available Hemangiomas of the urinary tract can arise anywhere along the system. These rare benign lesions can cause life-threatening severe hematuria. We  present an 11-year-old girl with recurrent multiple bladder hemangioma treated with fulguration and review of the literature.  

  17. Eleven Years of Primary Health Care Delivery in an Academic Nursing Center.

    Science.gov (United States)

    Hildebrandt, Eugenie; Baisch, Mary Jo; Lundeen, Sally P.; Bell-Calvin, Jean; Kelber, Sheryl

    2003-01-01

    Client visits to an academic community nursing center (n=25,495) were coded and analyzed. Results show expansion of nursing practice and services, strong case management, and management of illness care. The usefulness of computerized clinical documentation system and of the Lundeen conceptional model of community nursing care was demonstrated.…

  18. Sustaining Eleven Years of Counter-Improvised Explosive Device Relevancy for Tomorrow’s War

    Science.gov (United States)

    2013-04-30

    and above (3 5 hours). • Metal Detector Operators Course for NCO aud below (8 hours per detector) and Metal Detector Leaders Course for NCO aud...above for Marines assigned to operate and/or le.ad/supetvi~. metal detector operation:; (8 how·s). • Operate a Robot in an IED Environment Course for

  19. Eleven generations of selection for the duration of fertility in the intergeneric crossbreeding of ducks.

    Science.gov (United States)

    Cheng, Yu-Shin; Rouvier, Roger; Liu, Hsiao-Lung; Huang, Shang-Chi; Huang, Yu-Chia; Liao, Chung-Wen; Liu Tai, Jui-Jane; Tai, Chein; Poivey, Jean-Paul

    2009-03-31

    A 12-generation selection experiment involving a selected line (S) and a control line (C) has been conducted since 1992 with the aim of increasing the number of fertile eggs laid by the Brown Tsaiya duck after a single artificial insemination (AI) with pooled Muscovy semen. On average, 28.9% of the females and 17.05% of the males were selected. The selection responses and the predicted responses showed similar trends. The average predicted genetic responses per generation in genetic standard deviation units were 0.40 for the number of fertile eggs, 0.45 for the maximum duration of fertility, and 0.32 for the number of hatched mule ducklings' traits. The fertility rates for days 2-8 after AI were 89.14% in the S line and 61.46% in the C line. Embryo viability was not impaired by this selection. The largest increase in fertility rate per day after a single AI was observed from d5 to d11. In G12, the fertility rate in the selected line was 91% at d2, 94% at d3, 92% at days 3 and 4 then decreased to 81% at d8, 75% at d9, 58% at d10 and 42% at d11. In contrast, the fertility rate in the control line showed an abrupt decrease from d4 (74%). The same tendencies were observed for the evolution of hatchability according to the egg set rates. It was concluded that selection for the number of fertile eggs after a single AI with pooled Muscovy semen could effectively increase the duration of the fertile period in ducks and that research should now be focused on ways to improve the viability of the hybrid mule duck embryo.

  20. Eleven generations of selection for the duration of fertility in the intergeneric crossbreeding of ducks

    Directory of Open Access Journals (Sweden)

    Liu Tai Jui-Jane

    2009-03-01

    Full Text Available Abstract A 12-generation selection experiment involving a selected line (S and a control line (C has been conducted since 1992 with the aim of increasing the number of fertile eggs laid by the Brown Tsaiya duck after a single artificial insemination (AI with pooled Muscovy semen. On average, 28.9% of the females and 17.05% of the males were selected. The selection responses and the predicted responses showed similar trends. The average predicted genetic responses per generation in genetic standard deviation units were 0.40 for the number of fertile eggs, 0.45 for the maximum duration of fertility, and 0.32 for the number of hatched mule ducklings' traits. The fertility rates for days 2–8 after AI were 89.14% in the S line and 61.46% in the C line. Embryo viability was not impaired by this selection. The largest increase in fertility rate per day after a single AI was observed from d5 to d11. In G12, the fertility rate in the selected line was 91% at d2, 94% at d3, 92% at days 3 and 4 then decreased to 81% at d8, 75% at d9, 58% at d10 and 42% at d11. In contrast, the fertility rate in the control line showed an abrupt decrease from d4 (74%. The same tendencies were observed for the evolution of hatchability according to the egg set rates. It was concluded that selection for the number of fertile eggs after a single AI with pooled Muscovy semen could effectively increase the duration of the fertile period in ducks and that research should now be focused on ways to improve the viability of the hybrid mule duck embryo.

  1. Measurements of diversity gain and radiation efficiency of the eleven antenna by using different measurement techniques

    DEFF Research Database (Denmark)

    Yang, Jian; Pivnenko, Sergey; Laitinen, Tommi

    2010-01-01

    This paper presents measurement results of diversity gain and radiation efficiency by using three different measurement techniques: reverberation chamber, spherical near-field anechoic chamber, and multi-probe anechoic chamber. The results are measured over a large 2–8 GHz bandwidth which...

  2. Explaining variation in perceived team effectiveness: Results from eleven quality improvement collaboratives

    NARCIS (Netherlands)

    M.M.H. Strating (Mathilde); A.P. Nieboer (Anna)

    2013-01-01

    textabstractAims and objectives. Explore effectiveness of 11 collaboratives focusing on 11 different topics, as perceived by local improvement teams and to explore associations with collaborative-, organisational- and team-level factors. Background. Evidence underlying the effectiveness of quality

  3. Focal fibrocartilaginous dysplasia ("fibrous periosteal inclusion"): an additional series of eleven cases and literature review.

    Science.gov (United States)

    Jouve, Jean-Luc; Kohler, Remi; Mubarak, Scott J; Nelson, Scott C; Dohin, Bruno; Bollini, Gerard

    2007-01-01

    Focal fibrocartilaginous dysplasia (FFCD) is a benign condition first described in 1985 as a cause of tibia vara. We are reporting on 11 cases. The lesions involved proximal tibia (9 cases), distal femur (1 case), and distal ulna (1 case). We believe that this entity represents a bony anchor preventing natural sliding of the periosteum during growth (an "epiphysiodesis-like" effect). For the tibia, we believe this is the pes anserinus. We are suggesting that this entity be called a "fibrous periostal inclusion." Treatment indications result from this concept: (1) for tibial lesions with a metaphyseal-diaphyseal angle less than 20 degrees observation for 6 to 12 months; (2) if the deformity improves, the tether likely broke spontaneously, and no treatment is required; and (3) curettage early if the deformity worsens. This will be followed by rapid correction into physiological valgus (tibia) and prevent the need for osteotomy. Early curettage for other less common locations is recommended.

  4. Interim Use Limitations for Eleven Threatened or Endangered Species in the San Francisco Bay Area

    Science.gov (United States)

    Interim use limitations may apply to pesticide products containing any of 75 active ingredients, in 8 listed counties. The limitations are in a Stipulated Injunction entered by the U.S. District Court for the Northern District of California in 2010.

  5. Diagnostic procedures and treatment of eleven dogs with peritoneal infections caused by Mesocestoides spp.

    Science.gov (United States)

    Crosbie, P R; Boyce, W M; Platzer, E G; Nadler, S A; Kerner, C

    1998-12-01

    An 8-year-old spayed Schnauzer with a distended abdomen was examined because of straining to urinate and suspected urinary tract infection. Abdominal radiography revealed a ground-glass appearance, and ultrasonography revealed numerous cystic structures in the peritoneal cavity. Examination of an aspirate of abdominal fluid revealed tissues consistent with metacestodes. Tissues were definitively identified as Mesocestoides spp on the basis of polymerase chain reaction amplification of restriction fragment length polymorphisms. The dog required several courses of treatment with fenbendazole to eliminate the infection. This was 1 of 11 dogs infected with Mesocestoides metacestodes. Treatment involving the use of praziquantel and albendazole were ineffective, but fenbendazole successfully cleared Mesocestoides infections in 5 of 6 dogs.

  6. Immunohistochemical identification and crossreactions of amyloid-A fibril protein in man and eleven other species

    NARCIS (Netherlands)

    Gruys, E.; Linke, R.P.; Hol, P.R.; Geisel, O.; Nathrath, W.B.J.; Trautwein, G.

    1984-01-01

    Antisera were prepared in rabbits, sheep or chicken against purified amyloid fibril protein AA from man, mouse, stone marten, dog, cow and hamster. These antisera were tested by immunodiffusion against all purified antigens and applied to tissue sections containing amyloid from man, mouse, hamster,

  7. Reactivity of eleven anti-human leucocyte monoclonal antibodies with lymphocytes from several domestic animals

    DEFF Research Database (Denmark)

    Aasted, Bent; Blixenkrone-Møller, Merete; Larsen, Else Bang

    1988-01-01

    Nine commercially available monoclonal antibodies and two monoclonal antibodies from The American Type Culture Collection, raised against various human leucocyte surface antigens, were tested on lymphocytes from cow, sheep, goat, swine, horse, cat, dog, mink, and rabbit as well as man. Four...... antibodies bound to lymphocytes from some of the animals. These were the antibodies against CD8 and CD4 antigen, the antibody to C3b-receptor, and the antibody to the HLA-DR antigen. The CD8 antigen-reactive antibody reacted with lymphocytes from mink, cat, dog, and sheep, while the CD4 antigen...

  8. Vektlegging av lesing i naturfaget. Del 2: Hvordan fremme elevens kompetanse i å lese naturfaglige tekster?

    Directory of Open Access Journals (Sweden)

    Stein Dankert Kolstø

    2012-06-01

    Full Text Available This article offers a tool-kit for science teachers reading instruction in science. The tool-kit is based on the importance of knowledge of text structures and skilled use of reading strategies for reading comprehension. Furthermore, the tool-kit takes into account the characteristics of the nature of science and scientific texts. By drawing upon insights from research on reading and reading instruction, the article directs attention to research which concludes that proper instruction increase students’ competency in reading expository texts with understanding. The article thus concludes that, in order to induce a change in school science towards increased focus on reading scientific texts, competencies related to reading need to be included among the learning goals in the science curriculum.

  9. Cuttlebone morphology limits habitat depth in eleven species of Sepia (Cephalopoda: Sepiidae).

    Science.gov (United States)

    Sherrard, K M

    2000-06-01

    The cuttlebone is a rigid buoyancy tank that imposes a depth limit on Sepia, the only living speciose cephalopod genus with a chambered shell. Sections of 59 cuttlebones from a geographically diverse sample of 11 species were examined using confocal microscopy. Sepia species that live at greater depths had thicker septa and less space between pillars than did shallow species. A plate theory analysis of cuttlebone strength based on these two measures predicted maximum capture depths accurately in most species. Thus cuttlebone morphology confers differing degrees of strength against implosion from hydrostatic pressure, which increases with increasing habitat depth. Greater strength may come at the cost of increased cuttlebone density, which impinges on the cuttlebone's buoyancy function.

  10. Community Energy Systems and the Law of Public Utilities. Volume Eleven. Florida

    Energy Technology Data Exchange (ETDEWEB)

    Feurer, D A; Weaver, C L

    1981-01-01

    A detailed description is given of the laws and programs of the State of Florida governing the regulation of public energy utilities, the siting of energy generating and transmission facilities, the municipal franchising of public energy utilities, and the prescription of rates to be charged by utilities including attendant problems of cost allocations, rate base and operating expense determinations, and rate of return allowances. These laws and programs are analyzed to identify impediments which they may present to the implementation of Integrated Community Energy Systems (ICES). This report is one of fifty-one separate volumes which describe such regulatory programs at the Federal level and in each state as background to the report entitled Community Energy Systems and the Law of Public Utilities - Volume One: An Overview. This report also contains a summary of a strategy described in Volume One - An Overview for overcoming these impediments by working within the existing regulatory framework and by making changes in the regulatory programs to enhance the likelihood of ICES implementation.

  11. Spinning-induced Rhabdomyolysis: Eleven Case Reports and Review of the Literature.

    Science.gov (United States)

    Kim, Daejin; Ko, Eun-Jung; Cho, HyeJeong; Park, Su Hyung; Lee, Sang Hwan; Cho, Nam-Gil; Lee, So-Young; Jeong, Hye Yun; Yang, Dong Ho

    2015-12-01

    Non-traumatic exertional rhabdomyolysis (exRML) occurs in individuals with normal muscles when the energy supplied to the muscle is insufficient. Here, we report 11 cases of spinning-induced rhabdomyolysis and review related literature. Spinning is a kind of indoor bicycle sport. The 11 patients who were diagnosed with exRML and admitted to CHA Bundang Medical Center were female and their ages ranged from 15 to 46 years. Two to three days prior to the presentation, the patients had attended a spinning class for the first time. All the patients had been otherwise healthy without any known medical illnesses. They were successfully treated without any complications, except mild non-symptomatic hypocalcemia. However, in the literature, severe complications such as compartment syndrome or acute kidney injury had been reported in relation to exRML including spinning-induced rhabdomyolysis. This spinning exercise needs prior guidelines and specific warnings to prevent exertional rhabdomyolysis.

  12. Story of a School: A Headmaster's Experiences with Children Aged Seven to Eleven.

    Science.gov (United States)

    Ministry of Education, London (England).

    The experiences of a headmaster of a primary junior school situated in the older part of a large city are described. The point is made that the children in this school, with but little conscious awareness of what was beautiful, had within them an ability to create true beauty within all the media of the arts. This booklet is divided into eight…

  13. Successes and challenges from formation to implementation of eleven broad-extent conservation programs.

    Science.gov (United States)

    Beever, Erik A; Mattsson, Brady J; Germino, Matthew J; Burg, Max Post Van Der; Bradford, John B; Brunson, Mark W

    2014-04-01

    Integration of conservation partnerships across geographic, biological, and administrative boundaries is increasingly relevant because drivers of change, such as climate shifts, transcend these boundaries. We explored successes and challenges of established conservation programs that span multiple watersheds and consider both social and ecological concerns. We asked representatives from a diverse set of 11 broad-extent conservation partnerships in 29 countries 17 questions that pertained to launching and maintaining partnerships for broad-extent conservation, specifying ultimate management objectives, and implementation and learning. Partnerships invested more funds in implementing conservation actions than any other aspect of conservation, and a program's context (geographic extent, United States vs. other countries, developed vs. developing nation) appeared to substantially affect program approach. Despite early successes of these organizations and benefits of broad-extent conservation, specific challenges related to uncertainties in scaling up information and to coordination in the face of diverse partner governance structures, conflicting objectives, and vast uncertainties regarding future system dynamics hindered long-term success, as demonstrated by the focal organizations. Engaging stakeholders, developing conservation measures, and implementing adaptive management were dominant challenges. To inform future research on broad-extent conservation, we considered several challenges when we developed detailed questions, such as what qualities of broad-extent partnerships ensure they complement, integrate, and strengthen, rather than replace, local conservation efforts and which adaptive management processes yield actionable conservation strategies that account explicitly for dynamics and uncertainties regarding multiscale governance, environmental conditions, and knowledge of the system? © 2014 Society for Conservation Biology.

  14. Eleven-year cyclicity of the sun on the 2000-year time scale

    Science.gov (United States)

    Nagovitsyn, Yu. A.; Georgieva, K.; Osipova, A. A.; Kuleshova, A. I.

    2015-12-01

    The paper describes the first reconstruction of the annual values of the total area and magnetic flux of sunspots, as well as the Wolf index, on the 2000-year time scale. The procedure was performed by combining data on solar cyclicity amplitudes obtained from a decadal reconstruction (Usoskin et al., 2014) and data on its phases acquired from the numbers of auroras, which is contained in catalogs by Křivský and Silverman.

  15. Welfare program organization and legitimacy. A comparison of eleven OECD countries

    Directory of Open Access Journals (Sweden)

    Calzada, Inés

    2012-04-01

    Full Text Available The main objective of this paper is to analyze the relationship between the institutionalisation of the Welfare State (WS and its legitimacy, that is, until what extent the way of organising welfare programs have an impact on citizen’s perceptions of these programs and, hence, on the size and composition of the legitimacy basis of the WS. In order to comply with this objective the paper is organised as follows: first we will present data showing the cross-country variation in support for three main welfare programs (health care, old-age pensions, unemployment benefits; then we will analyse until what extent high levels of legitimacy are achieved through cross-class coalitions or cross-ideology coalitions. Finally we evaluate the impact of different program characteristics on the aggregate level of popular support each program achieves.

    El objetivo principal de este artículo es analizar la relación entre la institucionalización del estado del bienestar (eb y su legitimidad, es decir, hasta qué punto la forma de organizar el eb afecta a las percepciones que los ciudadanos desarrollan sobre el mismo y, de esta manera, modifica el tamaño y composición de sus bases de apoyo. A fin de cumplir con este objetivo el artículo se estructura de la siguiente forma: en primer lugar presentamos un panorama de la variación internacional en las actitudes hacia tres programas de bienestar (sanidad, pensiones y desempleo. Seguidamente estudiaremos de dónde proviene el apoyo extra que algunos programas consiguen, centrándonos específicamente en comprobar si una alta legitimidad se logra mediante la construcción de consensos inter-clases o inter-ideologías. terminaremos evaluando qué características organizativas concretas son las que correlacionan con el nivel de apoyo popular que un programa recibe.

  16. Asbestos Air Monitoring Results at Eleven Family Housing Areas throughout the United States.

    Science.gov (United States)

    1991-05-23

    asbest laboratory blank which on subsequent 14. "Matrix"-Fiber or fibers with one which may interfere with the analys analysis has an average of less...These will be designated asbest il. Examine the grid at low It is reloaded Into the microscope and a structures and will be classified as magnification

  17. Eleven novel polymorphic microsatellite DNA markers from the green-lipped mussel Perna viridis.

    Science.gov (United States)

    Ong, C C; Teh, C H; Tan, S G; Yusoff, K; Yap, C K

    2008-04-01

    We report on the characterization of 11 polymorphic microsatellite loci in P. viridis, the first set of such markers developed and characterized for this species. The number of alleles per locus ranged from 2 to 7, whereas the observed heterozygosity ranged from 0.0447 to 0.4837. These markers should prove useful as powerful genetic markers for this species.

  18. Eleven Strategies for Reducing Negative Responses to Price Increases for Public Park and Recreation Services

    National Research Council Canada - National Science Library

    John L Crompton

    2010-01-01

      It is now widely recognized that a cognitive processing approach is likely to be more useful for guiding park and recreation pricing decisions than the traditional approach of using neoclassical economic models...

  19. Remote Sensing of Cloud Top Height from SEVIRI: Analysis of Eleven Current Retrieval Algorithms

    Science.gov (United States)

    Hamann, U.; Walther, A.; Baum, B.; Bennartz, R.; Bugliaro, L.; Derrien, M.; Francis, P. N.; Heidinger, A.; Joro, S.; Kniffka, A.; hide

    2014-01-01

    The role of clouds remains the largest uncertainty in climate projections. They influence solar and thermal radiative transfer and the earth's water cycle. Therefore, there is an urgent need for accurate cloud observations to validate climate models and to monitor climate change. Passive satellite imagers measuring radiation at visible to thermal infrared (IR) wavelengths provide a wealth of information on cloud properties. Among others, the cloud top height (CTH) - a crucial parameter to estimate the thermal cloud radiative forcing - can be retrieved. In this paper we investigate the skill of ten current retrieval algorithms to estimate the CTH using observations from the Spinning Enhanced Visible and InfraRed Imager (SEVIRI) onboard Meteosat Second Generation (MSG). In the first part we compare ten SEVIRI cloud top pressure (CTP) data sets with each other. The SEVIRI algorithms catch the latitudinal variation of the CTP in a similar way. The agreement is better in the extratropics than in the tropics. In the tropics multi-layer clouds and thin cirrus layers complicate the CTP retrieval, whereas a good agreement among the algorithms is found for trade wind cumulus, marine stratocumulus and the optically thick cores of the deep convective system. In the second part of the paper the SEVIRI retrievals are compared to CTH observations from the Cloud-Aerosol LIdar with Orthogonal Polarization (CALIOP) and Cloud Profiling Radar (CPR) instruments. It is important to note that the different measurement techniques cause differences in the retrieved CTH data. SEVIRI measures a radiatively effective CTH, while the CTH of the active instruments is derived from the return time of the emitted radar or lidar signal. Therefore, some systematic differences are expected. On average the CTHs detected by the SEVIRI algorithms are 1.0 to 2.5 kilometers lower than CALIOP observations, and the correlation coefficients between the SEVIRI and the CALIOP data sets range between 0.77 and 0.90. The average CTHs derived by the SEVIRI algorithms are closer to the CPR measurements than to CALIOP measurements. The biases between SEVIRI and CPR retrievals range from -0.8 kilometers to 0.6 kilometers. The correlation coefficients of CPR and SEVIRI observations vary between 0.82 and 0.89. To discuss the origin of the CTH deviation, we investigate three cloud categories: optically thin and thick single layer as well as multi-layer clouds. For optically thick clouds the correlation coefficients between the SEVIRI and the reference data sets are usually above 0.95. For optically thin single layer clouds the correlation coefficients are still above 0.92. For this cloud category the SEVIRI algorithms yield CTHs that are lower than CALIOP and similar to CPR observations. Most challenging are the multi-layer clouds, where the correlation coefficients are for most algorithms between 0.6 and 0.8. Finally, we evaluate the performance of the SEVIRI retrievals for boundary layer clouds. While the CTH retrieval for this cloud type is relatively accurate, there are still considerable differences between the algorithms. These are related to the uncertainties and limited vertical resolution of the assumed temperature profiles in combination with the presence of temperature inversions, which lead to ambiguities in the CTH retrieval. Alternative approaches for the CTH retrieval of low clouds are discussed.

  20. Antidiabetic screening and scoring of eleven plants traditionally used in South Africa

    CSIR Research Space (South Africa)

    Van de Venter, M

    2008-09-01

    Full Text Available C12 muscle cells measuring glucose utilisation in all three cell lines and toxicity in the hepatocytes and adipocytes only. A scoring system was devised to aid interpretation of results. Catharanthus roseus results correlated with previously reported...

  1. Paget's Disease is Associated with Eleven Cancerous Regions: a Case Report and Therapeutic Strategy

    Institute of Scientific and Technical Information of China (English)

    Yongxi SONG; Zhenning WANG; Huimian XU; Zhenyu YUE; Chengzhong XING

    2009-01-01

    Paget's disease of the breast is an uncommon disorder that accounts for 1% to 3% of all mammary tumors. The incidence of underlying carcinoma associated with Paget's disease has been re-ported in 82% to 100% of cases. The finding of underlying carcinoma reaches almost 100% when a palpable lump is also present. In this rare case, we described a patient presenting with Paget's disease but no palpable lump. However, we found 11 independent regions which were all invasive ductal carci-noma after the operation. Considering this patient, we should pay more attention to a multifocal and multicentric breast carcinoma associated with Paget's disease. Furthermore, we believe the mammog-raphy examination and a modified radical mastectomy are the most appropriate treatments for this population in clinical practice.

  2. Remote Sensing of Cloud Top Height from SEVIRI: Analysis of Eleven Current Retrieval Algorithms

    Science.gov (United States)

    Hamann, U.; Walther, A.; Baum, B.; Bennartz, R.; Bugliaro, L.; Derrien, M.; Francis, P. N.; Heidinger, A.; Joro, S.; Kniffka, A.; Le Gleau, H.; Lockhoff, M.; Lutz, H.-J.; Meirink, J. F.; Minnis, P.; Palikonda, R.; Roebeling, R.; Thoss, A.; Platnick, S.; Watts, P.; Wind, G.

    2014-01-01

    The role of clouds remains the largest uncertainty in climate projections. They influence solar and thermal radiative transfer and the earth's water cycle. Therefore, there is an urgent need for accurate cloud observations to validate climate models and to monitor climate change. Passive satellite imagers measuring radiation at visible to thermal infrared (IR) wavelengths provide a wealth of information on cloud properties. Among others, the cloud top height (CTH) - a crucial parameter to estimate the thermal cloud radiative forcing - can be retrieved. In this paper we investigate the skill of ten current retrieval algorithms to estimate the CTH using observations from the Spinning Enhanced Visible and InfraRed Imager (SEVIRI) onboard Meteosat Second Generation (MSG). In the first part we compare ten SEVIRI cloud top pressure (CTP) data sets with each other. The SEVIRI algorithms catch the latitudinal variation of the CTP in a similar way. The agreement is better in the extratropics than in the tropics. In the tropics multi-layer clouds and thin cirrus layers complicate the CTP retrieval, whereas a good agreement among the algorithms is found for trade wind cumulus, marine stratocumulus and the optically thick cores of the deep convective system. In the second part of the paper the SEVIRI retrievals are compared to CTH observations from the Cloud-Aerosol LIdar with Orthogonal Polarization (CALIOP) and Cloud Profiling Radar (CPR) instruments. It is important to note that the different measurement techniques cause differences in the retrieved CTH data. SEVIRI measures a radiatively effective CTH, while the CTH of the active instruments is derived from the return time of the emitted radar or lidar signal. Therefore, some systematic differences are expected. On average the CTHs detected by the SEVIRI algorithms are 1.0 to 2.5 kilometers lower than CALIOP observations, and the correlation coefficients between the SEVIRI and the CALIOP data sets range between 0.77 and 0.90. The average CTHs derived by the SEVIRI algorithms are closer to the CPR measurements than to CALIOP measurements. The biases between SEVIRI and CPR retrievals range from -0.8 kilometers to 0.6 kilometers. The correlation coefficients of CPR and SEVIRI observations vary between 0.82 and 0.89. To discuss the origin of the CTH deviation, we investigate three cloud categories: optically thin and thick single layer as well as multi-layer clouds. For optically thick clouds the correlation coefficients between the SEVIRI and the reference data sets are usually above 0.95. For optically thin single layer clouds the correlation coefficients are still above 0.92. For this cloud category the SEVIRI algorithms yield CTHs that are lower than CALIOP and similar to CPR observations. Most challenging are the multi-layer clouds, where the correlation coefficients are for most algorithms between 0.6 and 0.8. Finally, we evaluate the performance of the SEVIRI retrievals for boundary layer clouds. While the CTH retrieval for this cloud type is relatively accurate, there are still considerable differences between the algorithms. These are related to the uncertainties and limited vertical resolution of the assumed temperature profiles in combination with the presence of temperature inversions, which lead to ambiguities in the CTH retrieval. Alternative approaches for the CTH retrieval of low clouds are discussed.

  3. Eleven years of breeding efforts to combat cassava brown streak disease.

    Science.gov (United States)

    Kawuki, Robert Sezi; Kaweesi, Tadeo; Esuma, Williams; Pariyo, Anthony; Kayondo, Ismail Siraj; Ozimati, Alfred; Kyaligonza, Vincent; Abaca, Alex; Orone, Joseph; Tumuhimbise, Robooni; Nuwamanya, Ephraim; Abidrabo, Philip; Amuge, Teddy; Ogwok, Emmanuel; Okao, Geoffrey; Wagaba, Henry; Adiga, Gerald; Alicai, Titus; Omongo, Christopher; Bua, Anton; Ferguson, Morag; Kanju, Edward; Baguma, Yona

    2016-09-01

    Cassava (Manihot esculenta Crantz) production is currently under threat from cassava brown streak disease (CBSD), a disease that is among the seven most serious obstacles to world's food security. Three issues are of significance for CBSD. Firstly, the virus associated with CBSD, has co-evolved with cassava outside its center of origin for at least 90 years. Secondly, that for the last 74 years, CBSD was only limited to the low lands. Thirdly, that most research has largely focused on CBSD epidemiology and virus diversity. Accordingly, this paper focuses on CBSD genetics and/or breeding and hence, presents empirical data generated in the past 11 years of cassava breeding in Uganda. Specifically, this paper provides: 1) empirical data on CBSD resistance screening efforts to identify sources of resistance and/or tolerance; 2) an update on CBSD resistance population development comprising of full-sibs, half-sibs and S1 families and their respective field performances; and 3) insights into chromosomal regions and genes involved in CBSD resistance based on genome wide association analysis. It is expected that this information will provide a foundation for harmonizing on-going CBSD breeding efforts and consequently, inform the future breeding interventions aimed at combating CBSD.

  4. Successes and challenges from formation to implementation of eleven broad-extent conservation programs

    Science.gov (United States)

    Beever, Erik A.; Bradford, John B.; Germino, Matthew J.; Mattsson, Brady J.; Post van der Burg, Max; Brunson, Mark

    2014-01-01

    Integration of conservation partnerships across geographic, biological, and administrative boundaries is increasingly relevant because drivers of change, such as climate shifts, transcend these boundaries. We explored successes and challenges of established conservation programs that span multiple watersheds and consider both social and ecological concerns. We asked representatives from a diverse set of 11 broadextent conservation partnerships in 29 countries 17 questions that pertained to launching and maintaining partnerships for broad-extent conservation, specifying ultimate management objectives, and implementation and learning. Partnerships invested more funds in implementing conservation actions than any other aspect of conservation, and a program’s context (geographic extent, United States vs. other countries, developed vs. developing nation) appeared to substantially affect program approach. Despite early successes of these organizations and benefits of broad-extent conservation, specific challenges related to uncertainties in scaling up information and to coordination in the face of diverse partner governance structures, conflicting objectives, and vast uncertainties regarding future system dynamics hindered long-term success, as demonstrated by the focal organizations. Engaging stakeholders, developing conservation measures, and implementing adaptive management were dominant challenges. To inform future research on broad-extent conservation, we considered several challenges when we developed detailed questions, such as what qualities of broad-extent partnerships ensure they complement, integrate, and strengthen, rather than replace, local conservation efforts and which adaptive management processes yield actionable conservation strategies that account explicitly for dynamics and uncertainties regarding multiscale governance, environmental conditions, and knowledge of the system?

  5. Global patterns of domestic cannabis cultivation: sample characteristics and patterns of growing across eleven countries

    NARCIS (Netherlands)

    G.R. Potter; M.J. Barratt; A. Malm; M. Bouchard; T. Blok; A.S. Christensen; T. Decorte; V. Asmussen Frank; P. Hakkarainen; A. Klein; S. Lenton; J. Perälä; B. Werse; M. Wouters

    2016-01-01

    Aims: To provide an overview of: demographic characteristics; experiences with growing cannabis; methods and scale of growing operations; reasons for growing; personal use of cannabis and other drugs; participation in cannabis and other drug markets; contacts with the criminal justice system for res

  6. Haplotype analysis of seven Y-STRs (eleven loci) in two Japanese populations.

    Science.gov (United States)

    Yuasa, Isao; Irizawa, Yoshito; Nakamura, Hiroaki; Matusue, Aya; Umetsu, Kazuo

    2008-11-01

    We analyzed 11 Y-STR loci (DYS446, DYS447, DYS449, DYS450, DYS459a/b, DYS463 and DYS464a/b/c/d) in a total of 324 Japanese males from western and southern Japan. Gene diversity ranged from 0.958 at DYS464 in western Japan to 0.259 at DYS450 in southern Japan. A total of 272 different haplotypes were observed, of which 240 were found in single individuals. The overall haplotype diversity and discrimination capacity was 0.9982 and 0.8395, respectively.

  7. Teaching with Multiple Methods in Mind: Eleven Ways to Reach All Students

    Science.gov (United States)

    Vondracek, Mark

    2009-01-01

    Teachers know what a daunting job it can be to ensure that all students in a class learn effectively. In addition to the usual difficulties of gaining everyone's attention at once, instructors also run into the issue of preferred learning styles. In any classroom environment, the same topic is taught to multiple students, and each student may…

  8. Stellar Diameters and Temperatures V. Eleven Newly Characterized Exoplanet Host Stars

    CERN Document Server

    von Braun, Kaspar; van Belle, Gerard T; Kane, Stephen R; Jones, Jeremy; Farrington, Chris; Schaefer, Gail; Vargas, Norm; Scott, Nic; Brummelaar, Theo A ten; Kephart, Miranda; Gies, Douglas R; Ciardi, David R; Lopez-Morales, Mercedes; Mazingue, Cassidy; McAlister, Harold A; Ridgway, Stephen; Goldfinger, P J; Turner, Nils H; Sturmann, Laszlo

    2013-01-01

    We use near-infrared interferometric data coupled with trigonometric parallax values and spectral energy distribution fitting to directly determine stellar radii, effective temperatures, and luminosities for the exoplanet host stars 61 Vir, $\\rho$ CrB, GJ 176, GJ 614, GJ 649, GJ 876, HD 1461, HD 7924, HD 33564, HD 107383, and HD 210702. Three of these targets are M dwarfs. Statistical uncertainties in the stellar radii and effective temperatures range from 0.5% -- 5% and from 0.2% -- 2%, respectively. For eight of these targets, this work presents the first directly determined values of radius and temperature; for the other three, we provide updates to their properties. The stellar fundamental parameters are used to estimate stellar mass and calculate the location and extent of each system's circumstellar habitable zone. Two of these systems have planets that spend at least parts of their respective orbits in the system habitable zone: two of GJ 876's four planets and the planet that orbits HD 33564. We find ...

  9. Seventy-five trials and eleven systematic reviews a day: how will we ever keep up?

    Directory of Open Access Journals (Sweden)

    Hilda Bastian

    2010-09-01

    Full Text Available When Archie Cochrane reproached the medical profession for not having critical summaries of all randomised controlled trials, about 14 reports of trials were being published per day. There are now 75 trials, and 11 systematic reviews of trials, per day and a plateau in growth has not yet been reached. Although trials, reviews, and health technology assessments have undoubtedly had major impacts, the staple of medical literature synthesis remains the non-systematic narrative review. Only a small minority of trial reports are being analysed in up-to-date systematic reviews. Given the constraints, Archie Cochrane's vision will not be achieved without some serious changes in course. To meet the needs of patients, clinicians, and policymakers, unnecessary trials need to be reduced, and systematic reviews need to be prioritised. Streamlining and innovation in methods of systematic reviewing are necessary to enable valid answers to be found for most patient questions. Finally, clinicians and patients require open access to these important resources.

  10. Immunohistochemical identification and crossreactions of amyloid-A fibril protein in man and eleven other species

    OpenAIRE

    Gruys, E.; Linke, R.P.; Hol, P.R.; Geisel, O.; Nathrath, W.B.J.; Trautwein, G

    1984-01-01

    Antisera were prepared in rabbits, sheep or chicken against purified amyloid fibril protein AA from man, mouse, stone marten, dog, cow and hamster. These antisera were tested by immunodiffusion against all purified antigens and applied to tissue sections containing amyloid from man, mouse, hamster, guinea pig, rabbit, cat, dog, mink, stone marten, pine marten, cow and horse. The binding of the antibodies to amyloid in tissue sections was assessed by the indirect immunoperoxidase method. The s...

  11. Eleven medicated porridge therapies for obesity%肥胖症粥疗法11方

    Institute of Scientific and Technical Information of China (English)

    赵德贵

    2010-01-01

    @@ 肥胖可以说是一种疾病,如果发展到一定程度,就可能并发一疾病,如糖尿病、心脑血管病、动脉硬化等等,医学认为,用祛湿利水、活血行气、健脾的食药及促进新陈代谢,调理内分泌等方法,排除体内所积存的多余水分和毒素,就可达到瘦身的效果.下面介绍几则轻身减肥食粥疗法.

  12. Membrane's Eleven: heavy-atom derivatives of membrane-protein crystals

    DEFF Research Database (Denmark)

    Morth, Jens Preben; Sørensen, Thomas Lykke-Møller; Nissen, Poul

    2006-01-01

    , platinum(II) and trimethyllead compounds as being particularly useful. On the other hand, lanthanide and uranyl compounds are poorly represented, which may be a consequence of these compounds having aggressive effects in crystal-soaking procedures. Furthermore, the database highlights the variety...

  13. Australian Arrenurus (Acari, Hydrachnidia) with the description of eleven new species

    NARCIS (Netherlands)

    Smit, H.

    2010-01-01

    The following new species of the genus Arrenurus from Australia are described: Arrenurus glaucus, A. hyalinus, A. grampiansensis, A. indentatus, A. kakadu, A. neogereckei, A. niveensis, A. novaecambricus, A. pesici, A. pseudomargatellus and A. rotundicaudatus. The female of A. postmai Smit is descri

  14. Diagnosis of the Meckel-Gruber syndrome at eleven to fourteen weeks' gestation.

    Science.gov (United States)

    Sepulveda, W; Sebire, N J; Souka, A; Snijders, R J; Nicolaides, K H

    1997-02-01

    Our purpose was to examine the feasibility of diagnosing the Meckel-Gruber syndrome at 11 to 14 weeks' gestation, both in high-risk pregnancies and during routine ultrasonographic screening for fetal chromosomal abnormalities. The high-risk population consisted of 9 pregnancies in 7 women with previous pregnancies affected by the Meckel-Gruber syndrome. At 11 to 14 weeks' gestation, systematic ultrasonographic examinations of the fetal skull, brain, kidneys, bladder, hands, and feet were undertaken in each case. The low-risk population consisted of 21,477 self-referred pregnancies undergoing first-trimester ultrasonographic screening for chromosomal defects at 11 to 14 weeks' gestation. The triad of fetal occipital encephalocele, bilateral polycystic kidneys, and postaxial polydactyly was detected by transabdominal ultrasonography and confirmed by transvaginal scanning in 4 of the 9 pregnancies in the high-risk group. The parents were counseled of the likely recurrence of the Meckel-Gruber syndrome, and all elected to terminate the pregnancy by transcervical evacuation at 12 to 13 weeks. In the low-risk population the only case of Meckel-Gruber syndrome was identified at 13 weeks; in the remaining screened pregnancies there were no other cases of termination of pregnancy or neonatal death with the diagnosis of Meckel-Gruber syndrome. This report demonstrates that the Meckel-Gruber syndrome can be confidently detected at the 11- to 14-week scan in both high- and low-risk populations.

  15. Eleven new species of Athacryvac Braet & van Achterberg from the Neotropical Region (Hymenoptera, Braconidae, Rogadinae).

    Science.gov (United States)

    Shimbori, Eduardo Mitio; Shaw, Scott Richard; Almeida, Luis Felipe Ventura De

    2016-07-14

    The neotropical genus Athacryvac Braet & van Achterberg was recently described based on two species from French Guiana. Despite the resemblance of these species with the diverse and widespread genus Aleiodes, the authors opted to erect the new genus based on several synapomorphies. With the analysis of more comprehensive morphological and geographical variation we propose reclassifying Athacryvac as a subgenus within Aleiodes. In this paper we describe 11 new neotropical species of the subgenus Athacryvac: Aleiodes (Athacryvac) achterbergi Shimbori & Penteado-Dias sp. nov., Aleiodes (Athacryvac) amazoniensis Shimbori & Almeida sp. nov., Aleiodes (Athacryvac) braeti Shimbori & Shaw sp. nov., Aleiodes (Athacryvac) choco Shimbori sp. nov., Aleiodes (Athacryvac) donaldquickei Shimbori & Penteado-Dias sp. nov., Aleiodes (Athacryvac) gonzalezi Shimbori & Shaw sp. nov., Aleiodes (Athacryvac) paradoxus Shimbori & Penteado-Dias sp. nov., Aleiodes (Athacryvac) soaresi Shimbori & Penteado-Dias sp. nov., Aleiodes (Athacryvac) tico Shimbori & Shaw sp. nov., Aleiodes (Athacryvac) torresi Shimbori & Shaw sp. nov., Aleiodes (Athacryvac) zaldivari Shimbori & Almeida sp. nov. We also provide new morphological and distributional data for the previously described A. alternatus and A. fuscatus, as well as the description of the male of the later species. The 13 known species of Aleiodes (Athacryvac) stat. nov. are restricted to the Neotropical Region, ranging from southern Mexico to southern Brazil. With our current results, there are 104 described neotropical Aleiodes species.

  16. Adaptive list sequential sampling method for population-based observational studies

    Science.gov (United States)

    2014-01-01

    Background In population-based observational studies, non-participation and delayed response to the invitation to participate are complications that often arise during the recruitment of a sample. When both are not properly dealt with, the composition of the sample can be different from the desired composition. Inviting too many individuals or too few individuals from a particular subgroup could lead to unnecessary costs or decreased precision. Another problem is that there is frequently no or only partial information available about the willingness to participate. In this situation, we cannot adjust the recruitment procedure for non-participation before the recruitment period starts. Methods We have developed an adaptive list sequential sampling method that can deal with unknown participation probabilities and delayed responses to the invitation to participate in the study. In a sequential way, we evaluate whether we should invite a person from the population or not. During this evaluation, we correct for the fact that this person could decline to participate using an estimated participation probability. We use the information from all previously invited persons to estimate the participation probabilities for the non-evaluated individuals. Results The simulations showed that the adaptive list sequential sampling method can be used to estimate the participation probability during the recruitment period, and that it can successfully recruit a sample with a specific composition. Conclusions The adaptive list sequential sampling method can successfully recruit a sample with a specific desired composition when we have partial or no information about the willingness to participate before we start the recruitment period and when individuals may have a delayed response to the invitation. PMID:24965316

  17. Adaptive list sequential sampling method for population-based observational studies.

    Science.gov (United States)

    Hof, Michel H; Ravelli, Anita C J; Zwinderman, Aeilko H

    2014-06-25

    In population-based observational studies, non-participation and delayed response to the invitation to participate are complications that often arise during the recruitment of a sample. When both are not properly dealt with, the composition of the sample can be different from the desired composition. Inviting too many individuals or too few individuals from a particular subgroup could lead to unnecessary costs or decreased precision. Another problem is that there is frequently no or only partial information available about the willingness to participate. In this situation, we cannot adjust the recruitment procedure for non-participation before the recruitment period starts. We have developed an adaptive list sequential sampling method that can deal with unknown participation probabilities and delayed responses to the invitation to participate in the study. In a sequential way, we evaluate whether we should invite a person from the population or not. During this evaluation, we correct for the fact that this person could decline to participate using an estimated participation probability. We use the information from all previously invited persons to estimate the participation probabilities for the non-evaluated individuals. The simulations showed that the adaptive list sequential sampling method can be used to estimate the participation probability during the recruitment period, and that it can successfully recruit a sample with a specific composition. The adaptive list sequential sampling method can successfully recruit a sample with a specific desired composition when we have partial or no information about the willingness to participate before we start the recruitment period and when individuals may have a delayed response to the invitation.

  18. Studies in Tutoring.

    Science.gov (United States)

    Cloward, Robert D.

    This is the report of a demonstration tutorial project which was conducted in New York City as part of the Mobilization for Youth program. Eleven tutorial centers were established in neighborhood elementary schools, and 240 students from local academic and vocational high schools were hired to tutor 544 fourth- and fifth-grade pupils. Each center…

  19. Audubon Bird Study Program.

    Science.gov (United States)

    National Audubon Society, New York, NY.

    Included are a student reader, "The Story of Birds," a leaders' guide, a large colored Audubon bird chart, and a separate guide for the chart. The student reader is divided into eleven sections which relate to the various physical and behavioral features of birds such as feathers, feeding habits as related to the shape of bills and feet, nests,…

  20. Which model based on fluorescence quenching is suitable to study the interaction between trans-resveratrol and BSA?

    Science.gov (United States)

    Wei, Xin Lin; Xiao, Jian Bo; Wang, Yuanfeng; Bai, Yalong

    2010-01-01

    There are several models by means of quenching fluorescence of BSA to determine the binding parameters. The binding parameters obtained from different models are quite different from each other. Which model is suitable to study the interaction between trans-resveratrol and BSA? Herein, twelve models based fluorescence quenching of BSA were compared. The number of binding sites increasing with increased binding constant for similar compounds binding to BSA maybe one approach to resolve this question. For example, here eleven flavonoids were tested to illustrate that the double logarithm regression curve is suitable to study binding polyphenols to BSA.