Feasibility and effectiveness of unintended pregnancy prevention with low-dose mifepristone combined with misoprostol before expected menstruation.

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Li, Cui-Lan; Chen, Dun-Jin; Deng, Yi-Fan; Song, Li-Ping; Mo, Xue-Tang; Liu, Kai-Jie

2015-12-01

What is the efficacy of maintaining or restoring non-pregnant status with low-dose mifepristone combined with misoprostol administered before expected menstruation? Low-dose mifepristone and misoprostol administered at the time of expected menstruation was effective and safe in maintaining or restoring non-pregnant status, with no obvious menstrual disturbance. Menstrual regulation involves the medical or mechanical stimulation of uterine sloughing in women with up to 2-3 weeks of menstrual delay. Low-dose mifepristone plus misoprostol is efficacious for termination of ultra-early pregnancy (≤ 35 days of amenorrhoea) with no obvious menstrual disturbance. A total of 678 women fulfilled all criteria and were recruited. Seventeen women dropped out after deciding to remain pregnant and 11 others were lost to follow-up. Thus, data from 650 women who completed the procedure were included in analyses. Participants were enrolled at any time during their menstrual cycle and administered medication 1 day before expected menstruation. The end of the study was defined on a per-patient basis as the date of completion of the post-treatment menstrual cycle. The primary outcome was the efficacy of abortion induction (for pregnant women) or menstrual regulation (for non-pregnant women). Women with regular menstrual cycles (25-35 days) were voluntarily recruited for this study between February 2012 and December 2014. Serum β-hCG was measured before mifepristone intake. Mifepristone (50 mg) was administered orally 1 day before expected menstruation and 200 µg misoprostol was administered orally on the day of expected menstruation. Efficacy, disturbance in bleeding patterns in the treatment and post-treatment cycles, satisfaction with the treatment, and subsequent contraception preference were analysed. Retrospective analysis of serum β-hCG levels at admission indicated that 23.3% (158/678) of the women were pregnant. The success rate for pregnancy termination was 98.6% (136

Perceptions and practices on menstruation amongst Nigerian secondary school girls.

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Adinma, Echendu Dolly; Adinma, J I B

2008-04-01

This cross-sectional descriptive study was conducted amongst 550 secondary school girls in southeastern Nigeria to determine their perceptions, problems, and practices on menstruation. Majority of the students, (75.6%), were aged 15-17 years. Only 39.3% perceived menstruation to be physiological. Abdominal pain/discomfort, (66.2%), was the commonest medical problem encountered by the respondents, although 45.8% had multiple problems. Medical problems were most commonly discussed with the mother, (47.1%), and least commonly discussed with the teachers, 0.4%. Analgesics, (75.6%), were most commonly used to relieve menstrual pain. Only 10% of respondents used non-pharmacologic remedies. Unsanitary menstrual absorbents were used by 55.7% of the respondents. Menstruation perceptions are poor, and practices often incorrect. A multi-dimensional approach focusing on capacity building of mothers, and teachers on sexuality education skills; using religious organizations as avenues for sexuality education; and effectively using the Mass Media as reproductive health education channels are recommended towards improving adolescents' perceptions and practices on menstruation.

Menstruation and control of diabetes.

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Walsh, C H; Malins, J M

1977-01-01

Seventy per cent of the patients aged 45 years or under and suffering from diabetic ketoacidosis who were seen in one diabetic clinic over five years were women. The association of menstruation with ketoacidosis was assessed over two and a half years, and it was found that menstruation was associated with ketoacidosis more often than would be expected by chance (P less than 0-01). Two hundred women were interviewed and 76 observed that menstruation changed their diabetic control. Fifty-three found that control deteriorated and hyperglycaemia occurred, while 23 found that control improved and hypoglycaemia was a common problem. Menstruation appears to be an important factor in influencing control of diabetes. The mechanism of the changes observed has not yet been determined, but it seems to be a subject worthy of further investigation. PMID:406008

Body appreciation and attitudes toward menstruation.

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Chrisler, Joan C; Marván, Maria Luisa; Gorman, Jennifer A; Rossini, Meghan

2015-01-01

Menstruation is an important function of the female body, yet it has rarely been included in research on body image. As women's attitudes toward menstruation are so often negative, this study was designed to examine whether women with positive body image would have more positive attitudes toward menstruation. Seventy-two American women, ages 18-45 years, were recruited online to complete the Body Appreciation Scale (Avalos et al., 2005) and the Beliefs about and Attitudes toward Menstruation Scale (Marván et al., 2006) and to answer some questions about their interest in menstrual suppression. Linear regressions showed that higher scores on body appreciation predicted more positive attitudes toward and beliefs about menstruation, but were not related to interest in menstrual suppression. Our findings may be useful in designing interventions to increase women's comfort with their bodies and bodily functions. Copyright © 2014 Elsevier Ltd. All rights reserved.

Managing Menstruation: Moderating Role of Symptom Severity on Active Coping and Acceptance.

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Kennett, Deborah J; O'Hagan, Fergal T; Meyerhoff, Tanya J

2016-05-01

Although research has examined women's thoughts toward menstruation, the role passive and active coping strategies play in the acceptance of menses and getting-on with daily activities remains relatively unexplored. In total, 217 undergraduate females having normal regular monthly menstrual periods completed inventories assessing severity of menstrual symptoms, cognitive and emotional representation of health state, general and specific coping strategies, and acceptance. It was found that women having a more emotionally focused representation of menstruation (passive coping style) had a heightened belief that menstruation is debilitating and bothersome and, regardless of symptom severity, scored lower in acceptance of menstruation. Conversely, women using more active strategies to cope with menstrual symptoms were observed to be more generally resourceful and to conjunctively use more palliative coping strategies. More importantly, for women experiencing high levels of menstrual discomfort, use of active coping was associated with better acceptance and getting-on with everyday activities. © The Author(s) 2015.

Menstruation and suicide: a histopathological study.

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Leenaars, Antoon A; Dogra, T D; Girdhar, Shalini; Dattagupta, S; Leenaars, Lindsey

2009-01-01

Previous research, albeit limited, has reported mixed findings on the impact of menstruation cycle on suicidal behavior. The contribution of menstruation to completed suicide is also controversial; the studies are, in fact, very limited and are not carefully designed. To examine whether the menstruation cycle impacts on suicide. In order to explore this relationship, 56 autopsies on completed suicides in females were performed and matched to a control group of 44 females who had died from other causes, at the All India Institute of Medical Sciences in New Delhi. Histopathological examination, a method of collecting tissue from the uterus through biopsy, was used to determine the stage of the menstrual cycle. The results show that 25% of women who had died by suicide were menstruating at the time, compared to 4.5% of the control group; this is statistically (chi2) significant at the p Menstruation in the women who completed suicide, compared to a control group, appeared to have an association, though more research is warranted. Not only there are serious methodological problems in the study of menstruation and suicide (largely because of problematic tissue storage and examination), but also because of the need to understand the impact within a larger psychological, social, and cultural frame.

Influence of age, reproductive cycling status, and menstruation on the vaginal microbiome in baboons (Papio anubis).

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Uchihashi, M; Bergin, I L; Bassis, C M; Hashway, S A; Chai, D; Bell, J D

2015-05-01

The vaginal microbiome is believed to influence host health by providing protection from pathogens and influencing reproductive outcomes such as fertility and gestational length. In humans, age-associated declines in diversity of the vaginal microbiome occur in puberty and persist into adulthood. Additionally, menstruation has been associated with decreased microbial community stability. Adult female baboons, like other non-human primates (NHPs), have a different and highly diverse vaginal microbiome compared to that of humans, which is most commonly dominated by Lactobacillus spp. We evaluated the influence of age, reproductive cycling status (cycling vs. non-cycling) and menstruation on the vaginal microbiome of 38 wild-caught, captive female olive baboons (Papio anubis) by culture-independent sequencing of the V3-V5 region of the bacterial 16S rRNA gene. All baboons had highly diverse vaginal microbial communities. Adult baboons had significantly lower microbial diversity in comparison to subadult baboons, which was attributable to decreased relative abundance of minor taxa. No significant differences were detected based on cycling state or menstruation. Predictive metagenomic analysis showed uniformity in relative abundance of metabolic pathways regardless of age, cycle stage, or menstruation, indicating conservation of microbial community functions. This study suggests that selection of an optimal vaginal microbial community occurs at puberty. Since decreased diversity occurs in both baboons and humans at puberty, this may reflect a general strategy for selection of adult vaginal microbial communities. Comparative evaluation of vaginal microbial community development and composition may elucidate mechanisms of community formation and function that are conserved across host species or across microbial community types. These findings have implications for host health, evolutionary biology, and microbe-host ecosystems. © 2015 Wiley Periodicals, Inc.

Sweet Secrets: Stories of Menstruation.

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O'Grady, Kathleen; Wansbrough, Paula

This book combines short stories with clear, factual health information for adolescent females about menstruation and their bodily changes they are experiencing. It focuses on young girls' concerns and questions about menstruation and educates through a combination of the front matter and the stories themselves. Coming from different generations…

'We do not know': a qualitative study exploring boys perceptions of menstruation in India.

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Mason, Linda; Sivakami, Muthusamy; Thakur, Harshad; Kakade, Narendra; Beauman, Ashley; Alexander, Kelly T; van Eijke, Anna Maria; Laserson, Kayla F; Thakkar, Mamita B; Phillips-Howard, Penelope A

2017-12-08

In low-middle income countries and other areas of poverty, menstrual hygiene management (MHM) can be problematic for women and girls. Issues include lack of knowledge about menstruation and MHM, and stigma around menstruation, also access to affordable and absorbent materials; privacy to change; adequate washing, cleaning and drying facilities; as well as appropriate and accessible disposal facilities. In order to effect change and tackle these issues, particularly in patriarchal societies, males may need to become advocates for MHM alongside women. However, little is known about their knowledge and attitudes towards menstruation, which may need addressing before they can assist in acting as advocates for change. The present study was undertaken to explore knowledge and attitudes about menstruation among adolescent boys across India, in order to gauge their potential to support their 'sisters'. The study was undertaken across three states in India, chosen a priori to represent the cultural and socio-economic diversity. Qualitative data using focus group discussions with 85 boys aged 13-17 years, from 8 schools, was gathered. Data were analysed using thematic analysis. The results were organised into three main themes, reflecting the key research questions: boys' knowledge of menstruation, source of knowledge, and attitudes towards menstruation and menstruating girls. Knowledge comprised three aspects; biological function which were generally poorly understood; cultural rites which were recognized by all; and girls' behaviour and demeanour, which were noted to be withdrawn. Some boys learnt about puberty and menstruation as part of the curriculum but had concerns this was not in-depth, or was missed out altogether. Most gathered knowledge from informal sources, from overhearing conversations or observing cultural rituals. Few boys openly displayed a negative attitude, although a minority voiced the idea that menstruation is a 'disease'. Boys were mostly sympathetic

How Menstruation Is Shaping Girls' Education in Rural Nepal

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Basyal, Samrat

2016-01-01

With voices for women's education coming from around the globe, it is a real setback when girls are unable to attend schools during their menstruation or periods, a process they encounter every month. The absence of Nepalese rural female students from schools during their periods does not only have the biological aspect to it but incorporates a…

Inflammation, leukocytes and menstruation.

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Evans, Jemma; Salamonsen, Lois A

2012-12-01

Menstruation has many of the features of an inflammatory process. The complexity and sequence of inflammatory-type events leading to the final tissue breakdown and bleeding are slowly being unravelled. Progesterone has anti-inflammatory properties, and its rapidly declining levels (along with those of estrogen) in the late secretory phase of each non-conception cycle, initiates a sequence of interdependent events of an inflammatory nature involving local inter-cellular interactions within the endometrium. Intracellular responses to loss of progesterone (in decidualized stromal, vascular and epithelial cells) lead to decreased prostaglandin metabolism and loss of protection from reactive oxygen species (ROS). Increased ROS results in release of NFκB from suppression with activation of target gene transcription and increased synthesis of pro-inflammatory prostaglandins, cytokines, chemokines and matrix metalloproteinases (MMP). The resultant leukocyte recruitment, with changing phenotypes and activation, provide further degradative enzymes and MMP activators, which together with a hypoxic environment induced by prostaglandin actions, lead to the tissue breakdown and bleeding characteristic of menstruation. In parallel, at sites where shedding is complete, microenvironmentally-induced changes in phenotypes of neutrophils and macrophages from pro- to anti-inflammatory, in addition to induction of growth factors, contribute to the very rapid re-epithelialization and restoration of tissue integrity.

The effect of menstruation on psychiatric hospitalization.

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Weston, Jaclyn; Speroni, Karen Gabel; Ellis, Terri; Daniel, Marlon G

2012-07-01

This study evaluated the effect of menstruation on psychiatric hospitalization. We conducted a retrospective chart review of the medical records of 177 women who met the eligibility criteria. Data collected included demographic details, primary and secondary diagnoses, date of last menstrual period (LMP), medication adherence, psychiatric hospitalization length of stay, previous psychiatric admissions (including those related to menstruation), discharge referrals, and readmissions. The majority of women were admitted for major depression, were single, Caucasian, and had a mean age of 34. A disproportionate percentage (37%) of women had their LMP within 5 days of psychiatric hospitalization (p = 0.0006). The overall average length of stay was 4.37 days, and 48.3% had a previous psychiatric admission. Medication adherence was routinely not documented (77.4%). Psychiatric hospitalizations for women are significantly greater within 5 days of their LMP. Nursing education and improved documentation are warranted to decrease the potential for readmission. Copyright 2012, SLACK Incorporated.

Structural changes in endometrial basal glands during menstruation.

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Garry, R; Hart, R; Karthigasu, K A; Burke, C

2010-09-01

To prospectively observe the changes occurring in endometrial glandular morphology during menstrual shedding and regeneration. Prospective observational study. The academic gynaecological endoscopy unit of a university teaching hospital. Population Thirteen patients investigated for a variety of benign, non-infective gynaecological disorders during the active bleeding phase of the menstrual cycle. The morphological appearances of concurrent histological and scanning electron microscopic images of endometrium taken at different stages of the active bleeding phase of menstruation were studied and correlated with the simultaneous immunohistochemical expression of the Ki-67 proliferation marker and the CD68 marker of macrophage activity. Change in morphology of endometrial glands at various stages of menstruation. Endometrial glands within the basalis show evidence of apoptosis and associated macrophage activity immediately before and during menstruation. There is subsequent destruction and removal of old secretory glandular epithelial elements, and rapid replacement with new narrow glands lined with small epithelial cells. There is no evidence of mitotic cell division or expression of Ki-67 in the glandular cells during this replacement process, but there is evidence of marked macrophage activity prior to glandular cell loss. Early endometrial epithelial repair after menstruation is not a consequence of mitotic cell division. It occurs without evidence of Ki-67 expression. There is structural evidence of programmed cell death and intense macrophage activity associated with glandular remodelling. Dead epithelial cells are shed from the glands and accumulate within the endometrial cavity to be replaced by new small epithelial cells that appear to arise by differentiation of the surrounding stromal cells. We propose that these stromal cells are endometrial progenitor/stem cells.

Exacerbation of Behçet's syndrome and familial Mediterranean fever with menstruation.

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Guzelant, Gul; Ozguler, Yesim; Esatoglu, Sinem Nihal; Karatemiz, Guzin; Ozdogan, Huri; Yurdakul, Sebahattin; Yazici, Hasan; Seyahi, Emire

2017-01-01

Menstruation triggers several conditions such as migraine, recurrent aphthous stomatitis and acne vulgaris in healthy individuals. There is evidence that Behçet's syndrome (BS) and familial Mediterranean fever (FMF) may exacerbate during menstruation. The aim is to assess whether BS and FMF patients experience menstrual flares. Females of reproductive age with BS and FMF seen consecutively at the outpatient clinic of Cerrahpasa Medical Faculty at Istanbul, as well as apparently healthy hospital workers were studied using a standardised questionnaire. BS patients were asked whether they experienced increased skin-mucosa lesions during the menstrual period. A similar questionnaire assessing this time the frequency of abdominal pain, chest pain and fever attacks was given to the patients with FMF. The healthy controls received both questionnaires. A total of 200 BS patients, 240 FMF patients and 250 healthy controls were studied. The most commonly reported symptom among both BS patients (51%) and healthy controls (62%) was the acneiform lesion. At least 79% patients with FMF reported attacks with menstruation, notably abdominal pain which, majority thought, could be differentiated from dysmenorrhea. Additionally, 76% of healthy controls reported having abdominal pain consistent most probably with dysmenorrhea. This survey showed that, in 68% of the patients with BS at least one skin mucosa lesion was exacerbated with menstruation, this was most commonly acneiform lesion. Menstruation had a slightly stronger effect on FMF, triggering at least one symptom in 79%. The main limitation of the study was the self-reported assessment methodology.

The endocrine and paracrine control of menstruation.

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Henriet, Patrick; Gaide Chevronnay, Héloïse P; Marbaix, Etienne

2012-07-25

During the reproductive life, the human endometrium undergoes cycles of substantial remodeling including, at menstruation, a massive but delimited tissue breakdown immediately followed by scarless repair. The present review aims at summarizing the current knowledge on the endocrine and paracrine control of menstruation in the light of recent observations that undermine obsolete dogmas. Menstruation can be globally considered as a response to falling progesterone concentration. However, tissue breakdown is heterogeneous and tightly controlled in space and time by a complex network of regulators and effectors, including cytokines, chemokines, proteases and various components of an inflammatory response. Moreover, menstruation must be regarded as part of a complex and integrated mechanism of tissue remodeling including features that precede and follow tissue lysis, i.e. decidualization and immediate post-menstrual regeneration. The understanding of the regulation of menstruation is of major basic and clinical interest. Indeed, these mechanisms largely overlap with those controlling other histopathological occurrences of tissue remodeling, such as development and cancer, and inappropriate control of menstrual features is a major potential cause of two frequent endometrial pathologies (i.e. abnormal uterine bleeding and endometriosis). Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

Menstrual-Cycle and Menstruation Disorders in Episodic vs Chronic Migraine: An Exploratory Study.

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Spierings, Egilius L H; Padamsee, Aliya

2015-07-01

Migraine is a chronic condition of recurring moderate-to-severe headaches that affects an estimated 6% of men and 18% of women. The highest prevalence is in those 18-49 years of age, generally when women menstruate. It is divided into episodic and chronic migraine depending on the total number of headache days per month being 14 or less or 15 or more, respectively. Migraine has been associated with menorrhagia, dysmenorrhea, and endometriosis, the latter particularly in chronic migraine. We conducted a questionnaire survey of 96 women with migraine, 18-45 years old, to determine the occurrence of the menstrual-cycle disorders, oligomenorrhea, polymenorrhea, and irregular cycle, and the menstruation disorders, dysmenorrhea and menorrhagia, in episodic vs chronic migraine. The prevalence of menstrual-cycle disorders in general (41.2 vs 22.2%) and dysmenorrhea (51.0 vs 28.9%) was statistically significantly higher in the women with chronic migraine than in those with episodic migraine (P ≤ 0.05) (not corrected for multiple comparisons). Whether the migraine was menstruation sensitive, that is, the headaches consistently occurred or worsened with menstruation, did not impact the prevalence of menstrual disorders. We conclude that chronic migraine is possibly more often than episodic migraine associated with menstrual-cycle disorders in general and dysmenorrhea, without impact on menstruation sensitivity of the headaches. Wiley Periodicals, Inc.

Recovery of menstruation after long-term chemotherapy and endocrine therapy in pre-menopausal patients with breast cancer.

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Sakurai, Kenichi; Enomoto, Katsuhisa; Amano, Sadao

2011-04-01

A luteinizing hormone-releasing hormone (LH-RH) agonist and tamoxifen (TAM) are used in hormonal therapy following pre- and post-operative chemotherapy in pre-menopausal advanced breast cancer patients who are positive for hormone receptors. However, it remains to be clarified how often patients recover menstruation after long-term LH-RH agonist plus TAM therapy. In this study, the incidence of menstruation recovery after therapy was examined. The subjects included 125 pre-menopausal patients with breast cancer who were positive for hormone receptors and had undergone surgery at our institution. They were treated with four cycles of the CEF regimen and four cycles of docetaxel (Doc) before surgery as adjuvant chemotherapy. Thereafter, they were treated with an LH-RH agonist plus TAM for 24 months and followed to determine menstruation recovery. Menstruation resumed in 24 cases (19.2%) after the last LH-RH agonist treatment session. It took 7.3 ± 2.8 months for the patients to recover menstruation. The rate of menstruation recovery was 42.1% in patients aged 40 or younger and 9.2% in those aged 41 or older; the difference was significant. The period until menstruation recovery tended to be longer in older patients at the end of treatment. The menstruation recovery rate after therapy was higher in younger women. However, since ovarian function may be lost even in younger patients, the potential consequences of this therapy should be fully explained beforehand to patients who may wish to become pregnant.

Menstruation during a lifespan: A qualitative study of women's experiences.

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Brantelid, Ida Emilie; Nilvér, Helena; Alehagen, Siw

2014-01-01

Menstruation is a natural phenomenon for women during their reproductive years. Our aim was to describe women's experiences of menstruation across the lifespan. Qualitative interviews with a narrative approach were conducted with 12 women between 18 and 48 years of age in Sweden. Using thematic analysis, we found menstruation to be a complex phenomenon that binds women together. It is perceived as an intimate and private matter, which makes women want to conceal the occurrence of menstrual bleeding. Over time, menstruation becomes a natural part of women's lives and gender identity. Health professionals play a central role supporting women to deal with menstruation.

Lower lung function associates with cessation of menstruation: UK Biobank data.

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Amaral, André F S; Strachan, David P; Gómez Real, Francisco; Burney, Peter G J; Jarvis, Deborah L

2016-11-01

Little is known about the effect of cessation of menstruation on lung function. The aims of the study were to examine the association of lung function with natural and surgical cessation of menstruation, and assess whether lower lung function is associated with earlier age at cessation of menstruation.The study was performed in 141 076 women from the UK Biobank, who had provided acceptable and reproducible spirometry measurements and information on menstrual status. The associations of lung function (forced vital capacity (FVC), forced expiratory volume in 1 s (FEV 1 ), spirometric restriction (FVC menstruation and age at cessation of menstruation were assessed using regression analysis.Women who had natural cessation of menstruation showed a lower FVC (-42 mL; 95% CI -53- -30) and FEV 1 (-34 mL; 95% CI -43- -24) and higher risk of spirometric restriction (adjusted odds ratio 1.27; 95% CI 1.18-1.37) than women still menstruating. These associations were stronger in women who had had a hysterectomy and/or oophorectomy. The earlier the natural cessation of menstruation, the lower the lung function. There was no clear association of lung function with age at hysterectomy and/or oophorectomy. Airflow obstruction was not associated with cessation of menstruation.Lower lung function associates with cessation of menstruation, especially if it occurs early in life. Copyright ©ERS 2016.

Young women's attitudes toward continuous use of oral contraceptives: the effect of priming positive attitudes toward menstruation on women's willingness to suppress menstruation.

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Rose, Jennifer Gorman; Chrisler, Joan C; Couture, Samantha

2008-08-01

The present study investigated American women's attitudes toward menstrual suppression and the effect of priming attitudes toward menstruation on women's willingness to suppress menstruation. One hundred college women randomly were assigned to either a positive priming group or a negative priming group. The positive priming group first completed the menstrual joy questionnaire (MJQ) followed by a willingness to suppress menstruation (WSM) questionnaire, the beliefs and attitudes toward menstruation (BATM) questionnaire, the menstrual distress questionnaire (MDQ), and a demographic questionnaire. The negative priming group completed, in the following order: the MDQ, WSM, BATM, MJQ, and demographics. Priming affected women's reports of positive cycle-related changes on the MDQ, but not women's willingness to suppress menstruation. Higher scores on the MJQ, positive attitudes toward menstrual suppression, and previous oral contraceptive (OC) use were predictors of women's willingness to suppress menstruation. Women's primary source of information about menstrual suppression was "media," and their primary concern was "safety." Thus, researchers should continue to investigate the long-term effects of continuous OC use and to analyze information about menstrual suppression in the popular press.

Knowledge and awareness regarding menstruation and HIV/AIDS among schoolgoing adolescent girls.

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Jain, Rakhi; Anand, Puneet; Dhyani, Anuj; Bansal, Deshant

2017-01-01

Menstruation in our country is associated with various myths and restrictions leading to lack of awareness among adolescent girls. Insufficient menstrual hygiene practices are the cause of stress associated with menstruation and reproductive tract infections. Sexually transmitted infections and HIV/AIDS are not openly discussed in our society making adolescents vulnerable to them. To assess the knowledge of school going adolescent girls regarding menstrual hygiene and HIV/AIDS. Girls studying in class 8 th -12 th standard and who have attained menarche were included in the study. A predesigned questionnaire, which consisted of questions related to menstrual awareness and knowledge about HIV/AIDS was used for data collection. Data was analysed using SPSS software and results were interpreted into percentages. 282 girls took part in the study. Mean age of girls was 14.70 ± 1.5 years. Median age of girls was 15 years. Knowledge regarding menstrual hygiene and HIV/AIDS was found to be only satisfactory leaving a scope of improvement. Mother was the main source of information regarding both menstruation and HIV/AIDS. A comprehensive health education programme involving mothers is required to remove various misconceptions and taboos associated with menstruation and make it a pleasant experience for adolescent girls. Information, education and awareness programmes need to be strengthened to spread awareness regarding HIV/AIDS.

Knowledge and awareness regarding menstruation and HIV/AIDS among schoolgoing adolescent girls

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Rakhi Jain

2017-01-01

Full Text Available Introduction: Menstruation in our country is associated with various myths and restrictions leading to lack of awareness among adolescent girls. Insufficient menstrual hygiene practices are the cause of stress associated with menstruation and reproductive tract infections. Sexually transmitted infections and HIV/AIDS are not openly discussed in our society making adolescents vulnerable to them. Aim: To assess the knowledge of school going adolescent girls regarding menstrual hygiene and HIV/AIDS. Materials and Methods: Girls studying in class 8th-12th standard and who have attained menarche were included in the study. A predesigned questionnaire, which consisted of questions related to menstrual awareness and knowledge about HIV/AIDS was used for data collection. Data was analysed using SPSS software and results were interpreted into percentages. Results: 282 girls took part in the study. Mean age of girls was 14.70 ± 1.5 years. Median age of girls was 15 years. Knowledge regarding menstrual hygiene and HIV/AIDS was found to be only satisfactory leaving a scope of improvement. Mother was the main source of information regarding both menstruation and HIV/AIDS. Conclusion: A comprehensive health education programme involving mothers is required to remove various misconceptions and taboos associated with menstruation and make it a pleasant experience for adolescent girls. Information, education and awareness programmes need to be strengthened to spread awareness regarding HIV/AIDS.

Ambivalent sexism, attitudes towards menstruation and menstrual cycle-related symptoms.

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Marván, Ma Luisa; Vázquez-Toboada, Rocío; Chrisler, Joan C

2014-08-01

The objective of the present study was to investigate the relationship between ambivalent sexism and beliefs and attitudes towards menstruation, and, in turn, to study the influence of these variables on menstrual cycle-related symptoms. One hundred and six Mexican women completed the Ambivalent Sexism Inventory, the Beliefs about and Attitudes toward Menstruation Questionnaire and the Menstrual Distress Questionnaire. The higher scores on benevolent sexism were associated with the most positive attitudes towards menstruation and also with the belief that a menstruating woman should or should not do some activities and that menstruation keeps women from their daily activities. The higher scores on hostile sexism were associated with rejection of menstruation as well as with feelings of embarrassment about it. Beliefs about and attitudes towards menstruation predicted menstrual cycle-related symptoms related to negative affect, impaired concentration and behavioural changes, but did not predict somatic symptoms. These results will be useful to health professionals and advocates who want to change the negative expectations and stereotypes of premenstrual and menstrual women and reduce the sexism and negative attitudes towards women that are evident in Mexican culture. © 2013 International Union of Psychological Science.

Mexican adolescents' experience of menarche and attitudes toward menstruation: role of communication between mothers and daughters.

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Marván, M L; Molina-Abolnik, M

2012-12-01

First, to explore the kind of information that Mexican mothers give their daughters about menstruation before their menarche, and to study the impact of this communication on how prepared the daughters felt when they experienced their menarche. Second, to investigate the influence of the menarcheal experience on attitudes toward menstruation. Cross-sectional survey. Sample of adolescents attending 3 different public schools. 405 Mexican postmenarcheal adolescents, aged 12-15 years. Participants answered a questionnaire that had 3 parts: (a) General data, (b) topics related to menses that participants had discussed with their mothers prior to menarche, and (c) menarcheal experience. They also answered a questionnaire about menstrual attitudes. Although most of the participants knew what they should do when they experienced their menarche, only 39% stated they had felt prepared to start menstruating. Regarding menstrual attitudes, adolescents scored highest on Negative Feelings and Secrecy rather than on Positive Feelings. Participants who had previously discussed the emotional aspects of menses with their mothers were more likely to claim they had felt prepared to start menstruating when they got their first period (OR = 3.45). The fact that adolescents felt prepared to start menstruating predicted positive attitudes toward menstruation (β = .19) Discussing the emotional aspects of menses prior to menarche is crucial to being prepared for menarche, and to holding positive attitudes toward menstruation. Information on biological knowledge and practical aspects of menses needs to be supplemented with emotional issues. Copyright © 2012 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

Cultural and social practices regarding menstruation among adolescent girls.

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Kumar, Anant; Srivastava, Kamiya

2011-01-01

The study attempts to find out the existing social and cultural practices regarding menstruation, awareness levels, and the behavioral changes that come about in adolescent girls during menstruation, their perception about menarche, how do they treat it, and the various taboos, norms, and cultural practices associated with menarche. The study was conducted on 117 adolescent girls (age 11-20 years) and 41 mothers from various communities and classes in Ranchi comprising residential colonies and urban slums. The findings unfolds many practices: cultural and social restrictions associated with menstruation, myth, and misconception; the adaptability of the adolescent girls toward it; their reaction, reaction of the family; realization of the importance of menstruation; and the changes that have come in their life after menarche and their resistance to such changes. The article also suggests the strategies to improve menstrual health and hygiene among adolescent girls. The study concludes that cultural and social practices regarding menstruation depend on girls' education, attitude, family environment, culture, and belief.

SOCIAL ASPECTS OF MENSTRUATION RELATED PRACTICES IN ADOLESCENT GIRLS OF DISTRICT DEHRADUN

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Ruchi Juyal

2013-09-01

Full Text Available Context: Menstrual hygiene is an issue that every girl and woman has to deal with in her life, but there is lack of awareness on the process of menstruation. The taboos surrounding this issue in the society prevent girls and women from articulating their menstrual needs. It is now becoming increasingly recognized that the social and cultural significance of menstruation interacts with the physiological process to produce culturally determined norms and practices. Settings and Design: Cross-Sectional conducted in two randomly selected Inter colleges (one rural and one urban of district Dehradun of Uttarakhand state.Methods and Material: 453 girls studying in 9th to 12th grades were interviewed by using a prestructured and pretested questionnaire regarding various aspects of menstruation process.Statistical analysis used: percentages and Chi-square testResults: Most of the girls faced one or the other kind of social and / or religious restriction during their menstrual periods. Maximum restriction was observed in going to the temple (87.4 % followed by prohibition in touching pickles (48.6 %. These restrictions were equally reported by the urban and rural girls.Conclusions: Girls should be made aware regarding physiological basis of menstruation and a change in beliefs and attitudes need to be attained to ensure optimal behaviour and thereby prompting of a healthy menstrual life styles and practices.

Abnormal structure and functional connectivity of the anterior insula at pain-free periovulation is associated with perceived pain during menstruation.

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Dun, Wang-Huan; Yang, Jing; Yang, Ling; Ding, Dun; Ma, Xue-Ying; Liang, Feng-Li; von Deneen, Karen M; Ma, Shao-Hui; Xu, Xiao-Ling; Liu, Jixin; Zhang, Ming

2017-12-01

Neuroimaging studies have demonstrated the critical role of the insula in pain pathways and its close relation with the perceived intensity of nociceptive stimuli. We aimed to identify the structural and functional characteristics of the insula during periovulatory phase in women with primary dysmenorrhea (PDM), and further investigate its association with the intensity of perceived pain during menstruation. Optimized voxel-based morphometry and functional connectivity (FC) analyses were applied by using 3-dimensional T1-weighted and resting functional magnetic resonance imaging (fMRI) in 36 patients at the peri-ovulation phase and 29 age-, education-, and gender-matched healthy controls (HC). A visual analogue scale (VAS) was used to examine the intensity of the abdominal pain at periovulation and menstruation. In our results, PDM patients had significant higher VAS-rating during menstruaion than periovulation. Compared with the HC, PDM patients had lower gray matter density in the left anterior insula (aINS). Taken the left aINS as a seed region, we further found hypoconnectivity between aINS and medial prefrontal cortex (mPFC), which showed negative relation with the VAS during menstruation. As the aINS is a key site of the salience network (SN) and the mPFC is a critical region in the default mode network (DMN), it's implicated a trait-related central-alteration that communications between pain attention and perception networks were disrupted without the ongoing menstrual pain. Moreover, result of correlation analysis, at least in part, suggested a possible role of altered FC (pain-free period) in predicting pain perception (menstruation).

A missing piece: the spiny mouse and the puzzle of menstruating species.

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Bellofiore, Nadia; Cousins, Fiona; Temple-Smith, Peter; Dickinson, Hayley; Evans, Jemma

2018-07-01

We recently discovered the first known menstruating rodent. With the exception of four bats and the elephant shrew, the common spiny mouse ( Acomys cahirinus ) is the only species outside the primate order to exhibit menses. There are few widely accepted theories on why menstruation developed as the preferred reproductive strategy of these select mammals, all of which reference the evolution of spontaneous decidualisation prior to menstrual shedding. Though menstruating species share several reproductive traits, there has been no identifiable feature unique to menstruating species. Such a feature might suggest why spontaneous decidualisation, and thus menstruation, evolved in these species. We propose that a ≥3-fold increase in progesterone during the luteal phase of the reproductive cycle is a unique characteristic linking menstruating species. We discuss spontaneous decidualisation as a consequence of high progesterone, and the potential role of prolactin in screening for defective embryos in these species to aid in minimising implantation of abnormal embryos. We further explore the possible impact of nutrition in selecting species to undergo spontaneous decidualisation and subsequent menstruation. We summarise the current knowledge of menstruation, discuss current pre-clinical models of menstruation and how the spiny mouse may benefit advancing our understanding of this rare biological phenomenon. © 2018 Society for Endocrinology.

A Content Analysis of Educational Media about Menstruation.

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Havens, Beverly; Swenson, Ingrid

1989-01-01

Reviewed 31 audiovisual media for content related to physical and psychological aspects of menstruation; portrayal of adolescent girls, parents, and peers; and relationship of menstruation to developmental process. In general, variations in physical and emotional responses were described as normal. In all cases, fear and embarrassment were…

A cross-sectional study of the beliefs and attitudes towards menstruation of Chinese undergraduate males and females in Hong Kong.

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Wong, Wing Chi; Li, Mei Kuen; Chan, Wai Ying Veronica; Choi, Yuen Yu; Fong, Chi Hung Sandra; Lam, Ka Wah Kara; Sham, Wun Chi; So, Ping Ping; Wong, Kit; Yeung, Kuen Ha; Yeung, Tsz Yan

2013-12-01

To explore the beliefs and attitudes towards menstruation of Chinese undergraduates in Hong Kong and to compare those of (1) male and female undergraduates with those of (2) undergraduates studying health-related vs. nonhealth-related programmes. Menstruation is typically viewed as a forbidden topic or a troublesome experience. These negative beliefs and attitudes result from existing myths and taboos associated with cultural factors and health education levels. A cross-sectional survey was conducted in all universities in Hong Kong. Undergraduates were invited through convenience sampling to complete a questionnaire assessing their attitudes and beliefs towards menstruation. A questionnaire on 'beliefs about and attitudes towards menstruation' was adopted. Questionnaires were self-administered by the respondents. A total of 450 questionnaires were distributed, and a response rate of 96.6% was obtained; 416 completed questionnaires were collected and analysed. Many Chinese undergraduates agreed that menstruation is annoying, causes disability, involves prescription and proscription and is not pleasant. When comparing the beliefs and attitudes towards menstruation of Chinese male undergraduates with those of female undergraduates, females tended to disagree that menstruation should be maintained secret, but tended to agree that it was annoying. When comparing the beliefs and attitudes towards menstruation of Chinese undergraduates studying health-related programmes with those under nonhealth-related programmes, the latter group exhibited a higher level of belief in prescription and proscription for menstruation than the former group. Chinese undergraduates in Hong Kong were influenced by the traditional Chinese culture and social environment, resulting in negative attitudes towards menstruation. This study recommends that sex education, especially reproductive health education, be extended to tertiary education. This study provides relevant information on planning

Relationship between menstruation status and work conditions in Japan.

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Nishikitani, Mariko; Nakao, Mutsuhiro; Tsurugano, Shinobu; Inoure, Mariko; Yano, Eiji

2017-01-01

Menstrual problems can significantly impact daily and work life. In reaction to a shrinking population, the Japanese government is encouraging more women to participate in the labor force. Actual success in achieving this aim, however, is limited. Specifically, participation in the workforce by women during their reproductive years is impacted by their health, which involves not only work conditions, but also traditional family circumstances. Therefore, it is important to further assess and gather more information about the health status of women who work during their reproductive years in Japan. Specifically, women's health can be represented by menstruation status, which is a pivotal indicator. In this study, we assessed the association between short rest periods in work intervals and menstruation and other health status indicators among female workers in Japan. Study participants were recruited from the alumnae of a university, which provided a uniform educational level. All 9864 female alumnae were asked to join the survey and 1630 (17%) accepted. The final sample of study participants ( n  = 505) were aged 23-43 years, had maintained the same job status for at least 1 year, and were not shift workers, had no maternal status, and did not lack any related information. The participants were divided into two groups according to interval time, with 11 h between end of work and resumption of daily work as a benchmark. This interval time was based on EU regulations and the goal set by the government of Japan. Health outcomes included: menstrual cycle, dysmenorrhoea symptoms, anxiety regarding health, and satisfaction in terms of health. Multiple logistic regression analyses were conducted to estimate the odds ratios (ORs) and 95% confidence intervals (CIs) for health indexes in association with interval time by adjusting for confounding variables that included both psychosocial and biological factors. We compared the health status of women in the workforce with

Taiwanese adolescents' gender differences in knowledge and attitudes towards menstruation.

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Cheng, Ching-Yu; Yang, Kyeongra; Liou, Shwu-Ru

2007-06-01

The purpose of the study was to explore gender differences in knowledge and attitudes towards menstruation among Taiwanese adolescents. This study was a secondary data analysis of a cross-sectional comparison study conducted in Taiwan. A total of 287 female and 269 male students at a junior high school participated in the study. The results showed that almost all the students had heard about menstruation and most of them had received menstrual information at school. However, their knowledge about menstruation was not accurate. Moreover, the male students expressed more negative attitudes towards menstruation than the female students. Taboos were heard by most students and, although many female students doubted the reality of the taboos they had heard, they observed them anyway. The study calls for an evaluation of sex education and suggests more open discussions about menstruation among young people in those education sessions. In addition, school nurses and obstetrical/gynecological nurses should be involved more in adolescents' sexual education.

[Comparative study of reflectance spectroscopy of women's acupoints around menstruation].

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Jiang, Xing-Hui; Liu, Han-Ping; Guo, Zhou-Yi; Meng, Yao-Yong; Zeng, Chang-Chun; Liu, Song-Hao

2010-12-01

Acupoint was reaction of viscera and its optical parameter was an important characteristic of tissue. In the present work, in order to discuss specificity of acupuncture on the response of qi and blood in human body, we compared the diffuse reflectance of Taichong (LV3), Taibai (SP3), and Chongyang (ST42) before, during and after menstruation. All the acupoints had the same shape of the spectrum and troughs were all at 423.16, 544.06 and 577.47 nm. The values of reflectance during menstruation were greater than before and after menstruation, especially for SP3 and ST42 (P menstruation. Diffuse reflectance may be possibly used in the quantitative analysis of qi and blood.

Attitudes Towards Menstruation.

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Stevens, Gwendolyn; Gardner, Sheldon

To explore current conceptions about menstruation, 50 male and female undergraduate students were asked to Q sort symptoms from the Moos Menstrual Distress Questionnaire (MDQ). The MDQ is a scale which contains 47 symptoms which have been associated with the menstrual cycle. The Q sort is a statistical technique in which data are analyzed as…

Attitudes toward menstruation in females with schizophrenia or schizoaffective disorders in Taiwan.

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Liang, H-Y; Lee, L-W; Kelsen, B A; Hsu, S-C; Liu, C-Y; Chen, C-Y

2013-12-01

The aims of this cross-sectional, case-controlled, observational study were to examine attitudes toward menstruation in female patients with schizophrenia or schizoaffective disorder and in a control group, and to explore the associations between attitudes toward menstruation and psychopathology, menstrual regularity during antipsychotic treatment, and menstrual distress symptoms. Fifty-eight patients treated with anti-psychotic medications for at least the previous 6 months were placed in irregular (irregular menstrual cycle) (n = 31) and regular (regular menstrual cycle) (n = 27) groups. Sixty-two, age-matched, healthy female participants with regular menstrual cycles were enrolled as a control group. Psychopathology was assessed by psychiatrists using the Positive and Negative Syndrome Scale (PANSS). The Menstrual Attitude Questionnaire (MAQ) was used to assess attitudes toward menstruation, and symptom checklists based on the Moos Menstruation Distress Questionnaire (MMDQ) were used to assess menstrual distress symptoms. Patients with psychotic disorders (both irregular and regular groups) had more negative attitudes toward menstruation than the control group. In the Schizophrenia group, there was no association between the severity of psychotic symptoms and their influence on attitudes toward menstruation. Moreover, regular menstrual cycles during antipsychotic treatment and fewer menstrual distress symptoms were the two main predictors for more positive attitudes toward menstruation in the patient group. This is one of the first studies to explore the relationship between psychotic symptoms and attitudes toward menstruation. The findings provide more support for the assumption that attitudes toward menstruation are derived from a woman's perception of her bodily experience rather than a psychiatric disorder.

Cultural aspects and mythologies surrounding menstruation and abnormal uterine bleeding.

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Tan, Delfin A; Haththotuwa, Rohana; Fraser, Ian S

2017-04-01

The objective of this chapter is to present an overview of how menstruation, a normal bodily function, was and is perceived in various ethnic groups and cultures in the world, from ancient mythology, historical, or traditional practices to contemporary belief systems. Mythical tales about menstruation abound in the legends and prehistory of ancient cultures. These tales characterize menstrual blood variously as sacred, a gift from the gods, or a punishment for sin, but it is almost always magical and powerful. In contrast, most world religions view menstruation, with varying degrees of severity, as a major problem, a sign of impurity and uncleanliness, and therefore, menstruating women are isolated, prohibited from polluting the holy places, and shunned. Many of these myths and cultural misperceptions persist to the present day, reflected in a wide range of negative attitudes toward menstruation, which can have serious and direct implications for reproductive health. In view of the increasingly globalized nature of current clinical practice, it is crucial that health care providers are familiar with existing cultural and social views and attitudes toward the menstrual function. The ultimate goal is to be able to provide women culturally sensitive and medically appropriate therapies for their menstrual disorders. This biocultural approach to menstruation management is desirable in contemporary medical practice. Copyright © 2016. Published by Elsevier Ltd.

Attitudes and practices of school-aged girls towards menstruation.

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Jarrah, Samiha Suhail; Kamel, Andaleeb Abu

2012-06-01

The purpose of this study was to (i) investigate attitude and menstruation-related practices in Jordanian school-aged girls; (ii) identify the influence of premenstrual preparation on girls' attitude and menstruation-related practices. A descriptive cross-sectional design was used. Data was collected from a convenience sample of 490 school-age girls (12-18 years) from different districts in Jordan. Self-report instruments [Menstrual Attitude Questionnaire (MAQ), and Menstrual Practices Questionnaires (MPQ)] were used to assess the study variables. Descriptive statistics, correlation and chi-square tests were used to analyze the data. It was found that menstrual attitude and practices were positively correlated. Poor attitude toward menstruation and low menstrual practices were significantly associated with inadequate premenstrual preparation. There is a need to prepare girls for menstruation before menarche. The role of the schools and teachers should be reinforced through formal and well planned reproductive health educators for girls and their mothers. © 2012 Blackwell Publishing Asia Pty Ltd.

Menstruation, perimenopause, and chaos theory.

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Derry, Paula S; Derry, Gregory N

2012-01-01

This article argues that menstruation, including the transition to menopause, results from a specific kind of complex system, namely, one that is nonlinear, dynamical, and chaotic. A complexity-based perspective changes how we think about and research menstruation-related health problems and positive health. Chaotic systems are deterministic but not predictable, characterized by sensitivity to initial conditions and strange attractors. Chaos theory provides a coherent framework that qualitatively accounts for puzzling results from perimenopause research. It directs attention to variability within and between women, adaptation, lifespan development, and the need for complex explanations of disease. Whether the menstrual cycle is chaotic can be empirically tested, and a summary of our research on 20- to 40-year-old women is provided.

Menstrual socialization, beliefs, and attitudes concerning menstruation in rural and urban Mexican women.

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Marvan, Maria Luisa; Trujillo, Paulina

2010-01-01

Women living in rural and urban areas of Mexico answered a questionnaire about what they were told at home about menstruation before their menarche (first menstruation), and answered the Beliefs About and Attitudes Toward Menstruation Questionnaire. Around half of both urban and rural women were told that they were going to experience negative perimenstrual changes. There were fewer urban than rural women who were advised to do or not to do certain activities while menstruating. Menstrual socialization affected the beliefs and attitudes concerning menstruation held by women as adults. These findings are discussed in light of the sociocultural background of the participants.

Statistical testing of association between menstruation and migraine.

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Barra, Mathias; Dahl, Fredrik A; Vetvik, Kjersti G

2015-02-01

To repair and refine a previously proposed method for statistical analysis of association between migraine and menstruation. Menstrually related migraine (MRM) affects about 20% of female migraineurs in the general population. The exact pathophysiological link from menstruation to migraine is hypothesized to be through fluctuations in female reproductive hormones, but the exact mechanisms remain unknown. Therefore, the main diagnostic criterion today is concurrency of migraine attacks with menstruation. Methods aiming to exclude spurious associations are wanted, so that further research into these mechanisms can be performed on a population with a true association. The statistical method is based on a simple two-parameter null model of MRM (which allows for simulation modeling), and Fisher's exact test (with mid-p correction) applied to standard 2 × 2 contingency tables derived from the patients' headache diaries. Our method is a corrected version of a previously published flawed framework. To our best knowledge, no other published methods for establishing a menstruation-migraine association by statistical means exist today. The probabilistic methodology shows good performance when subjected to receiver operator characteristic curve analysis. Quick reference cutoff values for the clinical setting were tabulated for assessing association given a patient's headache history. In this paper, we correct a proposed method for establishing association between menstruation and migraine by statistical methods. We conclude that the proposed standard of 3-cycle observations prior to setting an MRM diagnosis should be extended with at least one perimenstrual window to obtain sufficient information for statistical processing. © 2014 American Headache Society.

Transient trimethylaminuria related to menstruation

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Shimizu, Makiko; Cashman, John R; Yamazaki, Hiroshi

2007-01-01

Background Trimethylaminuria, or fish odor syndrome, includes a transient or mild malodor caused by an excessive amount of malodorous trimethylamine as a result of body secretions. Herein, we describe data to support the proposal that menses can be an additional factor causing transient trimethylaminuria in self-reported subjects suffering from malodor and even in healthy women harboring functionally active flavin-containing monooxygenase 3 (FMO3). Methods FMO3 metabolic capacity (conversion of trimethylamine to trimethylamine N-oxide) was defined as the urinary ratio of trimethylamine N-oxide to total trimethylamine. Results Self-reported Case (A) that was homozygous for inactive Arg500stop FMO3, showed decreased metabolic capacity of FMO3 (i.e., ~10% the unaffected metabolic capacity) during 120 days of observation. For Case (B) that was homozygous for common [Glu158Lys; Glu308Gly] FMO3 polymorphisms, metabolic capacity of FMO3 was almost ~90%, except for a few days surrounding menstruation showing 90%) metabolic capacity, however, on days around menstruation the FMO3 metabolic capacity was decreased to ~60–70%. Conclusion Together, these results indicate that abnormal FMO3 capacity is caused by menstruation particularly in the presence, in homozygous form, of mild genetic variants such as [Glu158Lys; Glu308Gly] that cause a reduced FMO3 function. PMID:17257434

Women's attitudes about menstruation and associated health and behavioral characteristics.

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Morrison, Lynn A; Larkspur, Louona; Calibuso, Marites J; Brown, Susan

2010-01-01

To examine the relationships between attitudes towards menstruation, health, and behavioral characteristics. The 136 women who completed questionnaires varied in their sexual activity, sexual orientation, and use of hormonal contraception. Women's estimated cycle length was accurate when compared to observed cycle length (F (3,156) = .05; P = .98). Smokers had decreased durations of flow (P menstruation as natural compared to abstinent, sexually active heterosexuals or those using traditional oral contraception (F (5,141) = 2.43; P = .04). Hormonal contraception use, but not sexual orientation, was associated with attitudes about menstruation.

Endometrial haemostasis and menstruation.

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Davies, Joanna; Kadir, Rezan A

2012-12-01

Under normal physiological circumstances menstruation is a highly regulated, complex process that is under strict hormonal control. During normal menstruation, progesterone withdrawal initiates menstruation. The cessation of menstrual bleeding is achieved by endometrial haemostasis via platelet aggregation, fibrin deposition and thrombus formation. Local endocrine, immunological and haemostatic factors interact at a molecular level to control endometrial haemostasis. Tissue factor and thrombin play a key role locally in the cessation of menstrual bleeding through instigation of the coagulation factors. On the other hand, fibrinolysis prevents clot organisation within the uterine cavity while plasminogen activator inhibitors (PAI) and thrombin-activatable fibrinolysis inhibitors control plasminogen activators and plasmin activity. Abnormalities of uterine bleeding can result from imbalance of the haemostatic factors. The most common abnormality of uterine bleeding is heavy menstrual bleeding (HMB). Modern research has shown that an undiagnosed bleeding disorder, in particular von Willebrand disease (VWD) and platelet function disorders, can be an underlying cause of HMB. This has led to a change in the approach to the management of HMB. While full haemostatic assessment is not required for all women presenting with HMB, menstrual score and bleeding score can help to discriminate women who are more likely to have a bleeding disorder and benefit from laboratory haemostatic evaluation. Haemostatic agents (tranexamic acid and DDAVP) enhance systemic and endometrial haemostasis and are effective in reducing menstrual blood loss in women with or without bleeding disorders. Further research is required to enhance our understanding of the complex interactions of haemostatic factors in general, and specifically within the endometrium. This will lead to the development of more targeted interventions for the management of abnormal uterine bleeding in the future.

Place of menstruation in the reproductive lives of women of rural North India

Directory of Open Access Journals (Sweden)

Singh A

2006-01-01

Full Text Available Objective : To ascertain the perceptions and experiences of women regarding menstruation. Methods : An integrated qualitative and quantitative study on reproductive health of Indian women was conducted in two primary health centre areas of rural north India. Present article reports on the perceptions of 1205 women regarding various aspects of menstruation. Results : Major source of information about menarche/menstruation was friends/relatives (72%. Mean age at menarche was ~ 15 years. Very few women (0.4% used sanitary napkins. Majority of women had strong beliefs about effect of diet on menstruation. Most of them considered menstruation a dirty act and indulged in various taboo behaviours. Initial reaction was of fear/apprehension at menarche in majority of girls. Conclusion: Women in rural north India still hold tranditional beliefs regarding menstruation. Provision of a balanced and healthy family health education package to all girls is recommended.

[Survey on menopausal age and menstruation span in women in Pudong district of Shanghai].

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Chen, Hua; Feng, You-ji; Shu, Hui-min; Lu, Tian-mei; Zhu, Hong-mei; Yang, Bin-lie; Xiong, Miao

2010-06-01

To investigate natural spontaneous menopausal age, menstruation span and their relationship with menarche age and parity in Pudong district of Shanghai. From Jan 2007 to Jul 2008, 15 083 spontaneous menopause women undergoing cervical cancer screening were enrolled in this study. The questionnaire included menarche age, parity, spontaneous menopausal age and menstruation span. Those women were divided into four groups based on age, which were group of 56 - 60, 61 - 65, 66 - 70 and more than 70.Analysis of variance (ANOVA) was used for comparing difference between menopausal age and menstruation span. Multiple factor regressions was used to analyze the relationship between menarche age, parity and menopausal age and menstruation span. (1) Spontaneous menopausal age: the minimum was 29 years old, the maximum was 61 years old, and the mean age was (50.6 ± 3.7) years old. The mean spontaneous menopause age were (50.9 ± 3.4), (50.7 ± 3.7), (50.0 ± 4.1), (49.6 ± 4.0) years in groups of 56 - 60, 61 - 65, 66 - 70 and more than 70 years. With the increasing age range in four groups, the increasing trends of menopausal age were observed, which the difference of 1.36 year was shown between groups of 56 - 60 and more than 70 years. (2) Menstruation span: the mean of menstruation span was (34.3 ± 4.1) years, which the minimal age of 12 years and maximal age of 48 years were recorded. (34.6 ± 3.8), (34.3 ± 4.1), (33.9 ± 4.6), (33.2 ± 4.5) were observed in groups of 56 - 60, 61 - 65, 66 - 70 and more than 70 years. With the increasing age range in four groups, the increasing trends of menstruation span were observed, which the difference of 1.41 year was shown between groups of 56 - 60 and more than 70 years. (3) The impact of menarche age on menopausal age and menstruation span: there was no correlation between menarche age and menopausal age (r = 0.02); however, menstruation span was found to be negatively correlated with the menarche age (r = -0.43). (4) The impact

Painful menstrual periods

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Menstruation - painful; Dysmenorrhea; Periods - painful; Cramps - menstrual; Menstrual cramps ... into two groups, depending on the cause: Primary dysmenorrhea Secondary dysmenorrhea Primary dysmenorrhea is menstrual pain that ...

Young Adolescents' Beliefs Concerning Menstruation

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Clarke, Anne E.; Ruble, Diane N.

1978-01-01

A sample of 54 young adolescent girls (both pre- and postmenarcheal) and boys responded to a questionnaire assessing evaluative attitudes toward menstruation, expected symptomatology, perceived effects on moods and activities, and sources of information for these beliefs. (Author/JMB)

Molecular and functional aspects of menstruation in the macaque.

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Brenner, Robert M; Slayden, Ov D

2012-12-01

Much of our understanding of the molecular control of menstruation arises from laboratory models that experimentally recapitulate some, but not all, aspects of uterine bleeding observed in women. These models include: in vitro culture of endometrial explants or isolated endometrial cells, transplantation of human endometrial tissue into immunodeficient mice and the induction of endometrial breakdown in appropriately pretreated mice. Each of these models has contributed to our understanding of molecular and cellular mechanisms of menstruation, but nonhuman primates, especially macaques, are the animal model of choice for evaluating therapies for menstrual disorders. In this chapter we review some basic aspects of menstruation, with special emphasis on the macaque model and its relevance to the clinical issues of irregular and heavy menstrual bleeding (HMB).

The role of menstruation in women's objectification: a questionnaire study.

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Sveinsdóttir, Herdís

2017-06-01

The aim of this study was to investigate the concepts of objectification and self-objectification among young women in the context of attitudes towards menstruation, menstrual suppression, menstrual and menarche experiences, disorder eating and exercise habits and to detect predictors of objectification and self-objectification. The negative effects of objectification are well founded. Considering the central role menstruation plays in female biology, it comes as quite a surprise that so little attention is given to the subject in the research on objectification. Cross-sectional explorative survey design. A questionnaire that included the Self-Objectification Questionnaire, the Objectified Body Consciousness Scale, the Belief and Attitudes Towards Menstruation Questionnaire and the Suppress Menstruation subscale of the Attitudes Towards Menstrual Suppression Questionnaire was administered at the end of 2013 to 319 Icelandic women who represented the population by age. A stepwise multiple linear regression model was employed to calculate significant predictors of objectification and self-objectification. Four models of objectification are presented: the self-objectification model, the body surveillance model, the body shame model and the control belief model. Taken together, the strongest predictors of these models were related to eating habits. However, the findings also support the proposition that menstrual-related experiences influence women's objectification, particularly in terms of age at menarche, of belief in the prescriptive role of menstruation and of use of pain medication for menstrual pain. Healthcare providers in general and nurses in particular could and should assist girls and women in developing a positive view of their body and its reproductive functions by discussing the body and menstruation based on women's concerns. © 2016 John Wiley & Sons Ltd.

Associations of Age, BMI, and Years of Menstruation with Proximal Femur Strength in Chinese Postmenopausal Women: A Cross-Sectional Study

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Huili Kang

2016-01-01

Full Text Available This study aimed to elucidate the associations of age, BMI, and years of menstruation with proximal femur strength in Chinese postmenopausal women, which may improve the prediction of hip fracture risk. A cross-sectional study was conducted in 1322 Chinese postmenopausal women recruited from communities. DXA images were used to generate bone mineral density (BMD and geometric parameters, including cross-sectional area (CSA, outer diameter (OD, cortical thickness (CT, section modulus (SM, buckling ratio (BR at the narrow neck (NN, intertrochanter (IT, and femoral shaft (FS. Relationships of age, BMI, and years of menstruation with bone phenotypes were analyzed with the adjustment of height, age at menarche, total daily physical activity, education, smoking status, calcium tablet intake, etc. Age was associated with lower BMD, CSA, CT, SM, and higher BR (p < 0.05, which indicated a weaker bone strength at the proximal femur. BMI and years of menstruation had the positive relationships with proximal femur strength (p < 0.05. Further analyses showed that the ranges of absolute value of change slope per year, per BMI or per year of menstruation were 0.14%–1.34%, 0.20%–2.70%, and 0.16%–0.98%, respectively. These results supported that bone strength deteriorated with aging and enhanced with higher BMI and longer time of years of menstruation in Chinese postmenopausal women.

Reversible Suppression of Menstruation with Antiprogestins

National Research Council Canada - National Science Library

Brenner, Robert

2000-01-01

...) are compounds that bind to the P receptor and block P action. Continuous blockade of P action during the menstrual cycle by PAs would prevent progestational priming of the endometrium and thus inhibit menstruation...

Menstruation in Ulysses.

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Mullin, Katherine

2008-01-01

This article investigates James Joyce's fascination with a wide variety of medical texts, sexual folklores, religious beliefs, and persistent superstitions about menstruation. That fascination finds its way into Ulysses, which draws upon a number of intertexts to inform a curiosity about the female body most strikingly articulated by Bloom, Molly, and Gerty MacDowell. These intertexts are not simply imported into the novel but are dismantled and interrogated, as Joyce exposes, rather than endorses, clichés of essential femininity.

[Menstruation disorders more frequent in women with a history of sexual abuse

NARCIS (Netherlands)

Vink, C.W.; Labots-Vogelesang, S.M.; Lagro-Janssen, A.L.M.

2006-01-01

OBJECTIVE: To determine the relationship between menstruation disorders and prior sexual abuse. DESIGN: Questionnaire investigation. METHOD: A questionnaire was developed consisting of 50 questions about menstruation disorders, premenstrual syndrome and sexual abuse. The questionnaire was mailed to

Recurrent episcleritis in relation to menstruation: a case report.

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Rajoo, Sangeetha Govinda; Gandhewar, Jaishree

2011-09-01

To describe a case of recurrent episcleritis associated with a patient's menstrual cycle. A retrospective case review of a 39-year-old woman who presented with a 12-year history of recurrent episcleritis in relation to her menstruation. She was seen during an acute attack and started on a reducing regime of topical steroids for 5 weeks. She was then advised to use it a week before and after menstruation. Examination and investigations revealed episcleritis with a negative systems review. After starting the treatment, she was symptom free when reviewed at 4, 8, 14, and 33 weeks. Now, the patient uses topical steroids only 1 week before menstruation. Literature review revealed no recent case reports and provided insufficient evidence to understand this relationship. We recommend increased awareness and reporting because there is a need for more studies to understand this relationship and to provide evidence for management.

The forecasting of menstruation based on a state-space modeling of basal body temperature time series.

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Fukaya, Keiichi; Kawamori, Ai; Osada, Yutaka; Kitazawa, Masumi; Ishiguro, Makio

2017-09-20

Women's basal body temperature (BBT) shows a periodic pattern that associates with menstrual cycle. Although this fact suggests a possibility that daily BBT time series can be useful for estimating the underlying phase state as well as for predicting the length of current menstrual cycle, little attention has been paid to model BBT time series. In this study, we propose a state-space model that involves the menstrual phase as a latent state variable to explain the daily fluctuation of BBT and the menstruation cycle length. Conditional distributions of the phase are obtained by using sequential Bayesian filtering techniques. A predictive distribution of the next menstruation day can be derived based on this conditional distribution and the model, leading to a novel statistical framework that provides a sequentially updated prediction for upcoming menstruation day. We applied this framework to a real data set of women's BBT and menstruation days and compared prediction accuracy of the proposed method with that of previous methods, showing that the proposed method generally provides a better prediction. Because BBT can be obtained with relatively small cost and effort, the proposed method can be useful for women's health management. Potential extensions of this framework as the basis of modeling and predicting events that are associated with the menstrual cycles are discussed. © 2017 The Authors. Statistics in Medicine Published by John Wiley & Sons Ltd. © 2017 The Authors. Statistics in Medicine Published by John Wiley & Sons Ltd.

Adolescent girls define menstruation: a multiethnic exploratory study.

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Orringer, Kelly; Gahagan, Sheila

2010-09-01

Incomplete understanding of menstruation may place girls at risk for sexually transmitted diseases (STDs) and unintended pregnancy. Prior research suggests that European American and African American girls incompletely understand menstruation, yet little is known about menstrual knowledge in other ethnic groups. Using audiotaped focus group and individual interviews with 73 African American, Mexican American, Arab American, and European American girls, we assessed girls' menstrual understanding. Responses included reproduction, growing up, cleansing, messages about femininity, and not knowing. We found ethnic differences in the prominence of these themes. We learned that social and cultural factors play an important role in transmission of menstrual knowledge.

Menstruation, objectification and health-related quality of life: A questionnaire study.

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Sveinsdóttir, Herdís

2018-02-01

To explore young women's health-related quality of life (HRQOL) and investigate whether menstrual and menarche experiences and objectification predict mental and physical health components of HRQOL. Menstruation plays a fundamental role in female biology, in women's relationship to their bodies and consequently in women's health and their HRQOL. Cross-sectional explorative survey design. A questionnaire that included the SF-36v2, the Self-objectification Questionnaire (SOQ), the Body Surveillance and Body Shame subscales of the Objectified Body Consciousness Scale, the Belief and Attitudes Towards Menstruation Questionnaire (four subscales), and questions on menarche and menstruation was administered at the end of 2013 to 319 Icelandic women who represented the population by age. The SF-36v2 includes eight dimensions addressing the mental and physical components of HRQOL. Scores are presented as raw data scores and scores based on standardised score of American women and range from 0 to 100 with higher scores indicating better HRQL. A hierarchical multiple linear regression model was employed to calculate significant predictors of mental and physical health components of HRQOL. Mean raw data scores on SF36-v2 dimensions ranged from 54.7 to 91.5. The participants scored below the standardised, mean norm-based score for all dimensions. Secrecy of menstruation, experience of body shame and pain during menstruation predicted worse mental HRQOL. To believe in the proscriptive role and the unpleasantness of menstruation, experience of body shame, medication for menstrual pain and not holding a university education predicted worse physical HRQOL. These two models explained 30% and 22% of the variance of the mental and physical components of SF36-v2, respectively. Young women's mental and physical HRQOL is influenced by the specific context of their lives. Women's health education should take into account the various relationships women may have with their bodies. © 2017

Experiences and Constructions of Menarche and Menstruation Among Migrant and Refugee Women.

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Hawkey, Alexandra J; Ussher, Jane M; Perz, Janette; Metusela, Christine

2017-08-01

Experiences and constructions of menarche and menstruation are shaped by the sociocultural environment in which women are embedded. We explored experiences and constructions of menarche and menstruation among migrant and refugee women resettled in Sydney, Australia, and Vancouver, Canada. Seventy-eight semistructured individual interviews and 15 focus groups comprised of 82 participants were undertaken with women from Afghanistan, Iraq, Somalia, South Sudan, Sudan, Sri Lanka, and varying South American countries. We analyzed the data using thematic decomposition, identifying the overall theme "cycles of shame" and two core themes. In "becoming a woman," participants constructed menarche as a marker of womanhood, closely linked to marriage and childbearing. In "the unspeakable," women conveyed negative constructions of menstruation, positioning it as shameful, something to be concealed, and polluting. Identifying migrant and refugee women's experiences and constructions of menarche and menstruation is essential for culturally safe medical practice, health promotion, and health education.

Association between menstruation signs and anxiety, depression, and stress in school girls in Mashhad in 2011-2012

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Mohamadirizi, Soheila; Kordi, Masoumeh

2013-01-01

Background: Menstruation signs are among the most common disorders in adolescents and are influenced by various environmental and psychosocial factors. This study aimed to define the association between menstruation signs and anxiety, depression, and stress in school girls in Mashhad in 2011-2012. Materials and Methods: This was a cross-sectional study on 407 high school girls in Mashhad who were selected through two-step random sampling. The students completed a questionnaire concerning demographic characteristics, menstruation, Depression, Anxiety, and Stress Scale of 21 questions (DASS-21), and menstruation signs in three phases of their menstruation. Data were analyzed by the statistical tests of Pearson correlation coefficient, Student's t-test, one-way analysis of variance (ANOVA), and regression through SPSS version 14. Results: Based on the findings, 74% of the subjects reported pre-menstruation signs, 94% reported signs during bleeding, and 40.8% reported post-menstruation signs. About 44.3% of the subjects had anxiety, 45.5% had depression, and 47.2% had stress. In addition, Pearson correlation coefficient test showed a significant positive correlation between menstruation signs and depression, anxiety, and stress (P menstruation signs and psycho-cognitive variables, prevention and treatment of these disorders by the authorities of education and training and the Ministry of Health are essential. PMID:24403944

Association between menstruation signs and anxiety, depression, and stress in school girls in Mashhad in 2011-2012.

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Mohamadirizi, Soheila; Kordi, Masoumeh

2013-09-01

Menstruation signs are among the most common disorders in adolescents and are influenced by various environmental and psychosocial factors. This study aimed to define the association between menstruation signs and anxiety, depression, and stress in school girls in Mashhad in 2011-2012. This was a cross-sectional study on 407 high school girls in Mashhad who were selected through two-step random sampling. The students completed a questionnaire concerning demographic characteristics, menstruation, Depression, Anxiety, and Stress Scale of 21 questions (DASS-21), and menstruation signs in three phases of their menstruation. Data were analyzed by the statistical tests of Pearson correlation coefficient, Student's t-test, one-way analysis of variance (ANOVA), and regression through SPSS version 14. Based on the findings, 74% of the subjects reported pre-menstruation signs, 94% reported signs during bleeding, and 40.8% reported post-menstruation signs. About 44.3% of the subjects had anxiety, 45.5% had depression, and 47.2% had stress. In addition, Pearson correlation coefficient test showed a significant positive correlation between menstruation signs and depression, anxiety, and stress (P menstruation signs and psycho-cognitive variables, prevention and treatment of these disorders by the authorities of education and training and the Ministry of Health are essential.

Women with dysmenorrhoea are hypersensitive to experimentally induced forearm ischaemia during painful menstruation and during the pain-free follicular phase.

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Iacovides, S; Avidon, I; Baker, F C

2015-07-01

Monthly primary dysmenorrhoeic pain is associated with increased sensitivity to painful stimuli, particularly in deep tissue. We investigated whether women with dysmenorrhoea, compared with controls, have increased sensitivity to experimentally induced deep-tissue muscle ischaemia in a body area distant from that of referred menstrual pain. The sub-maximal effort tourniquet test was used to induce forearm ischaemia in 11 women with severe dysmenorrhoea and in nine control women both during menstruation and in the follicular phase of the menstrual cycle. Von Frey hair assessments confirmed the presence of experimental ischaemia. Women rated the intensity of menstrual and ischaemic pain on a 100-mm visual analogue scale. Women with dysmenorrhoea [mean (SD): 68 (20) mm] reported significantly greater menstrual pain compared with controls [mean (SD): 2 (6) mm; p = 0.0001] during the menstruation phase. They also rated their forearm ischaemic pain as significantly greater than the controls during the menstruation [dysmenorrhoeics vs. controls mean (SD): 58 (19) mm vs. 31 (21) mm, p menstruation phase and pain-free follicular phase. These findings suggest the presence of long-lasting changes in muscle pain sensitivity in women with dysmenorrhoea. Our findings that dysmenorrhoeic women are hyperalgesic to a clinically relevant, deep-muscle ischaemic pain in areas outside of referred menstrual pain confirm other studies showing long-lasting changes in pain sensitivity outside of the painful period during menstruation. © 2014 European Pain Federation - EFIC®

What They Should Know About Menstruation.

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McNab, Warren L.

1985-01-01

Lists common misconceptions about menstruation and suggests a unit on menstrual education. Activities and guidelines are presented along with unit outline. The outline consists of six major areas: definition and purpose; history; anatomy and reproduction; physiology; protection and discomfort; and related topics. (DH)

Imagery associated with menstruation in advertising targeted to adolescent women.

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Havens, B; Swenson, I

1988-01-01

Education about menstruation is not restricted to school instruction or information provided by adults and peers; exposure to advertisements in teen media provides imagery depicting menstruation and feminine role expectations. This paper analyzes the imagery in advertisements for sanitary products and products for the relief of menstrual symptoms. A 25% random sample of Seventeen magazine issues from 1976 to 1986 stratified by year were reviewed. A total of 135 ads for sanitary products and 32 ads for products for the relief of menstrual discomfort were analyzed. Each ad was examined for recurrent themes in text, context and tone. Data collected were examined for similarities in themes across both product type and time. The ads depict menstruation as a "hygienic crisis" that is best managed by an effective "security system" affording protection and "peace of mind." The failure of adequate protection places the woman at risk for soiling, staining, embarrassment and odor. Menstruating women are depicted as dynamic, energetic and always functioning at their optimal level. Such imagery may encourage guilt and diminished self-esteem in the adolescent who experiences discomfort. A lack of maternal, teacher or male figures in the ads is evident; the importance of peer support is reinforced.

Pattern of teen menstruation among secondary school girls in south east Nigeria.

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Nwokocha, Ada R C; Chinawa, Josephat M; Ubesie, Agozie C; Onukwuli, Vivian I; Manyike, Pius C

2016-03-01

Menstruation in the teenage age has assumed variable trends which is been influenced by several variables. This study is aimed at determining the pattern and trend of menstruation among teens attending secondary school in south east Nigeria and associated factors. Menstruation patterns were investigated using a stratified random sampling method of teens from junior secondary schools in Enugu, south east Nigeria. A self-administered questionnaire was developed and data analyzed using SPSS version 19. A total of 897 female teenagers aged 9-18 years completed the questionnaire with a mean age of 13.9±1.9 years. The mean age (SD) at onset of menarche was 12.5±1.2 years. Teenage girls with higher BMI achieved menarche earlier at age 8 and 9 when compared with their counterparts with lower BMI and this is statistically significant. F=7.60, df=8, p<0.001. Teens with a 14-day cycle had a higher BMI when compared with teens with longer cycle but this is not statistically significant. F=1.05, df=4, p=0.381. There is a statistical significance difference between teens duration of menstrual flow and BMI. Those with higher BMI had longer duration(4-5 days) compared with those with lower BMI. F=3.329, df=4, p=0.01 CONCLUSIONS: This study revealed that the mean age at onset of menarche was 12.5±1.2 years showing a continuing decreasing trend. Teens with higher BMI attain menarche earlier and had longer days of periods when compared with their counterpart with lower BMI.

Study on the Argument of "Menstruation" in Late Nineteenth-Century America : Focusing on M. P. Jacobi's The Question of Rest for Women during Menstruation

OpenAIRE

横山, 美和

2012-01-01

This article examines the argument concerning “menstruation” in late nineteenth-century America. With regard to an expansion of women's higher education, Sex in Education (1873) by Dr. Edward Clarke generated a controversy by stating that young women needed rest during menstruation; therefore the rigor of higher education would fail their health. Dr. Mary Putnam Jacobi refuted this argument in The Question of Rest for Women during Menstruation (1877). She attempted to combat the male research...

[Rehabilitation following interruption of pregnancy since the legalization of abortion. I. Structure of patients, duration of disability, menstruation and effects of contraceptive counseling].

Science.gov (United States)

Zwahr, C; Knorre, P; Kunz, L

1974-01-04

Rehabilitation after abortion is an important consideration for fertile women and is defined here as recovery of the physical, psychic, and social condition that had been present prior to abortion. 206 women were studied 6-12 months after induced abortion (before 12 weeks by the vacuum suction apparatus method). 9.2% of the women attributed worsening of their physical condition to recent abortion. Duration of work incapacity was 8-21 days, with an average of 19 days; younger women and women with fewer children recuperated more quickly. In most cases menstruation returned late, an average of 35 days after the last period. 33% of the menstruations were unusually heavy. Duration of menstruation decreased from an average of 6.5 days for the 1st period to an average of 5.4 days by the 6th, women over 30 became regular more quickly than younger women. The study revealed that 33% of the women did not use contraceptives even after abortion. After intensive counseling, a disappointing 22.9% still resisted using contraceptives.

Periodic safety analyses; Les essais periodiques

Energy Technology Data Exchange (ETDEWEB)

Gouffon, A; Zermizoglou, R

1990-12-01

The IAEA Safety Guide 50-SG-S8 devoted to 'Safety Aspects of Foundations of Nuclear Power Plants' indicates that operator of a NPP should establish a program for inspection of safe operation during construction, start-up and service life of the plant for obtaining data needed for estimating the life time of structures and components. At the same time the program should ensure that the safety margins are appropriate. Periodic safety analysis are an important part of the safety inspection program. Periodic safety reports is a method for testing the whole system or a part of the safety system following the precise criteria. Periodic safety analyses are not meant for qualification of the plant components. Separate analyses are devoted to: start-up, qualification of components and materials, and aging. All these analyses are described in this presentation. The last chapter describes the experience obtained for PWR-900 and PWR-1300 units from 1986-1989.

Cultural practices relating to menarche and menstruation among adolescent girls in Taiwan--qualitative investigation.

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Liu, H-L; Chen, K-H; Peng, N-H

2012-02-01

The aim of this study was to qualitatively record the cultural attitudes and practices associated with menarche and menstruation in Taiwanese girls, particularly with respect to coping mechanisms. Forty-eight adolescent girls participated. Adolescent girls were individually interviewed to investigate the effects of their cultural practices, coping mechanisms, and physiological symptoms during menarche and menstruation. The qualitative investigation revealed mixed reactions to menstruation, such as eating chocolate, using sanitary napkins, and feeling irritable or embarrassed. Cluster construction suggested that adolescents were prepared for menarche but required emotional support; in addition, the new generation employed the Internet to learn how to cope. A phenomenological approach showed that menarche and menstrual attitudes among Taiwanese adolescents were comprised in 4 dimensions: self-perception, information, and cultural practices with regard to menarche; physiological symptoms and psychological reactions during menstruation; coping mechanisms during menarche and menstruation; and methods for coping and cultural practices for menstruation. Cultural beliefs and the Internet have changed cross-cultural contacts. Educators and health professionals should seek to understand this generation of girls, who perceive the world as more flexible and available and have more creativity and new eating behaviors and hobbies. Copyright © 2012 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

Relationship between Female University Students' Knowledge on Menstruation and Their Menstrual Hygiene Practices: A Study in Tamale, Ghana

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Garti, Helene Akpene

2016-01-01

Positive perception about menstruation and good menstrual hygiene practice safeguards the health of postpubescent females by reducing their vulnerability to reproductive and urinary tract infections. Using a questionnaire, a cross-sectional study involving 293 randomly selected female undergraduate students in northern Ghana assessed the relationship between knowledge on menstruation and the practice of safe menstrual hygiene. Data collected was analyzed using GraphPad 5.01. This study found that although majority of respondents (73.4%) were aware of menstruation before menarche, most of them experienced fear and panic when it occurred. Mothers were the first to be informed when menstruation occurred, although teachers first provided them knowledge on menstruation. Respondents' knowledge on menstruation was average (57.3%) but their menstrual hygiene practice was good (80.2%). Age (p = 0.005) and course of study (p = 0.0008) significantly influenced respondents' knowledge on menstruation with older students as well as the medical and midwifery students being most knowledgeable. Muslim rather than Christian female students practiced better menstrual hygiene (p = 0.0001). Average knowledge score on menstruation indicated a deficit of knowledge on the anatomy and physiology of the female reproductive system. Increasing knowledge on menstruation had a positive and significant effect on practice of good menstrual hygiene. PMID:27525125

A Case for Critical Literacy Analysis of the Advertising Texts of Menstruation: Responding to Missed Opportunities

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Agnew, Shire; Sandretto, Susan

2016-01-01

When Agnew found the same, largely negative, dominant discourses of menstruation present in classroom lessons that researchers have been identifying for over 30 years, she sought different approaches to menstruation education. In this article the authors highlight the power of the media to (re)construct dominant discourses of menstruation and the…

Menstruation and menstrual hygiene among adolescent girls of West Bengal, India: A school based comparative study

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Adrija Datta

2012-11-01

Full Text Available Background: Adolescents are often less informed, less experienced, and less comfortable accessing reproductive health information and services than adults. In many developing countries, a culture of silence surrounds the topic of menstruation and related issues; as a result many young girls lack appropriate and sufficient information regarding menstrual hygiene. This may result in incorrect and unhealthy behaviour during their menstrual period. Objectives: To assess and compare knowledge, belief, ideas, source of knowledge and practice of menstrual hygiene between school-going adolescents in an urban and a rural school of West Bengal, India. Methods: Cross-sectional, descriptive study was conducted among adolescent female students of Howrah district of West Bengal, India in the year 2011. Data was collected by pre-designed, pre-tested semi-structured self administered questionnaire. Results: The mean age at menarche was 12.1 years among urban and 12.2 years among the rural participants. More than 80% participants had some restrictions imposed during menstruation. Significantly higher number of urban girls had pre-menarchal knowledge on menstruation and used sanitary napkins. Conclusions: Menstrual hygiene is a vital aspect of health education for adolescent girls. For improvement of menstrual hygiene, sanitary napkins should be made universally available and affordable.

Menstruation and menstrual hygiene among adolescent girls of West Bengal, India: A school based comparative study

Directory of Open Access Journals (Sweden)

Adrija Datta

2012-01-01

Full Text Available Background: Adolescents are often less informed, less experienced, and less comfortable accessing reproductive health information and services than adults. In many developing countries, a culture of silence surrounds the topic of menstruation and related issues; as a result many young girls lack appropriate and sufficient information regarding menstrual hygiene. This may result in incorrect and unhealthy behaviour during their menstrual period. Objectives: To assess and compare knowledge, belief, ideas, source of knowledge and practice of menstrual hygiene between school-going adolescents in an urban and a rural school of West Bengal, India. Methods: Cross-sectional, descriptive study was conducted among adolescent female students of Howrah district of West Bengal, India in the year 2011. Data was collected by pre-designed, pre-tested semi-structured self administered questionnaire. Results: The mean age at menarche was 12.1 years among urban and 12.2 years among the rural participants. More than 80% participants had some restrictions imposed during menstruation. Significantly higher number of urban girls had pre-menarchal knowledge on menstruation and used sanitary napkins. Conclusions: Menstrual hygiene is a vital aspect of health education for adolescent girls. For improvement of menstrual hygiene, sanitary napkins should be made universally available and affordable.

Males Perform Better in Identifying Voices During Menstruation Than Females: A Pilot Study.

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Wang, Xue; Xu, Xin; Liu, Yangyang

2016-10-01

The objective of the present study is to investigate gender differences in the ability to identify females' voice during menstruation. In Study 1, 55 male participants (M age = 19.6 years, SD = 1.0) were asked to listen to vocal samples from women during both ovulation and menstruation and to identify which recordings featured menstruating women. The results showed that the accuracy of men's responses (M = 56.73%, SD = 0.21) was significantly higher than 50%. In Study 2, 118 female students (M age = 19.4 years, SD = 1.6) completed the same task. The results indicated that the accuracy of women's performance was nearly 50%. These preliminary findings suggest that men are better able to identify women's voices during menstruation than women. Future work could consider several significant variables for the purpose of validating the results. © The Author(s) 2016.

[Changes of menstruation patterns and adverse effects during the treatment of LNG-IUS for symptomatic adenomyosis].

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Li, L; Leng, J H; Zhang, J J; Jia, S Z; Li, X Y; Shi, J H; Dai, Y; Zhang, J R; Li, T; Xu, X X; Liu, Z Z; You, S S; Chang, X Y; Lang, J H

2016-09-25

Objective: To investigate the changes of mestruation patterns and adverse effects during the treatment of levonorgestrel-releasing intrauterine system(LNG-IUS)for symptomatic adenomyosis in a prospective cohort study. Methods: From December, 2006 to December, 2014, patients of symptomatic adenomyosis diagnosed by transvaginal ultrasound in Peking Union Medical College Hospital were given LNG-IUS. Before and after placement of IUS, all patients' parameters were recorded, including carrying status of IUS, symptoms and scores of dysmenorrhea, menstruation scores, biochemical indicators, physical parameters, menstruation patterns and adverse effects. Risk factors for changes of menstruation patterns and adverse effects, and their impact on treatment effects were analyzed. Results: Totally 1 100 cases met inclusion criteria, with median age 36 years(range 20-44 years), median follow-up 35 months(range 1 -108 months). During follow-up changes of menstruation patterns increased significantly with amenorrhea and shortened-menstruation being the most common manifestations. On 3, 6, 12, 24, 36, 48 and 60 months after the placement of LNG-IUS, 0, 5.8%(43/744), 6.9%(47/682), 10.1%(60/595), 17.3%(87/502), 27.2%(104/383)and 29.6%(82/277)patients achieved amenorrhea respectively( P 12 months after placement, abdominal pain and body weight increasing ≥5 kg/year were the most common adverse effects. Changes of menstruation patterns, total and subclassifications of adverse effects were neither dependent on patient parameters, treatment modes and treatment effects, nor could predict future LNG-IUS carrying status(all P > 0.05). After taking out of LNG-IUS, most changes of menstruation and adverse effects disappeared. Conclusions: During the treatment of LNG-IUS for symptomatic adenomyosis, changes of menstruation patterns increase gradually with amenorrhea and shortened-menstruation being the most common manifestations, while adverse effects decrease significantly. Changes of

Caring for a Daughter with Intellectual Disabilities in Managing Menstruation: A Mother's Perspective

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Chou, Yueh-Ching; Lu, Zxy-Yann Jane

2012-01-01

Background: The concerns of mothers and their experiences while providing help to their daughters with intellectual disability (ID) and considerable support needs during menstruation have rarely been addressed. This qualitative study explored mothers' experiences and perceptions of managing their daughters' menstruation. Method: Twelve Taiwanese…

Redesigning Menstrual Education Programs Using Attitudes toward Menstruation.

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Kieren, Dianne K.

1992-01-01

Critiques current menstrual education efforts and reviews current data about the nature of adolescent girls' attitudes toward menstruation as the basis for redesigning comprehensive, effective menstrual education programs. (Author)

Chemotherapy-induced amenorrhea and the resumption of menstruation in premenopausal women with hormone receptor-positive early breast cancer.

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Koga, Chinami; Akiyoshi, Sayuri; Ishida, Mayumi; Nakamura, Yoshiaki; Ohno, Shinji; Tokunaga, Eriko

2017-09-01

For premenopausal women with breast cancer, information on the effects of chemotherapy and the risk of infertility is important. In this study, the effect of chemotherapy on the ovarian function in premenopausal women with hormone receptor-positive breast cancer was investigated, with an age-stratified analysis of the appearance of amenorrhea and the resumption of menstruation after the use of chemotherapy with anthracyclines or taxanes. Premenopausal women diagnosed with operable Stage I-III hormone receptor-positive breast cancer and underwent neoadjuvant or adjuvant chemotherapy with the standard regimen of anthracyclines and/or taxanes were included. The patients were classified into age groups in 5-year increments, and the rates of chemotherapy-induced amenorrhea (CIA), resumption of menstruation, and duration of CIA after chemotherapy were analyzed. The subjects consisted of 101 patients (median age 45 years). CIA occurred in 97 (96%) patients and 40 patients resumed menstruation. In all patients aged ≤39 years menstruation restarted, whereas in all patients aged ≥50 years, menstruation did not restart. For the patients who resumed menstruation, the younger the patients, the sooner menstruation tended to restart. The resumption of menstruation occurred within 1 year for younger patients aged around 30 years, but for those aged ≥35 years, 60% of cases took around 2-3 years for resumption. The incidence of CIA, the resumption of menstruation and duration of CIA after chemotherapy depend greatly on the patient's age.

Migraine Management During Menstruation and Menopause.

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MacGregor, E Anne

2015-08-01

Migraine is most prevalent in women during their reproductive years. An understanding of the effects of menstruation and menopause on migraine can enable neurologists to provide targeted and appropriate medical and hormonal strategies, enabling their patients to achieve better control of migraine and reduced disability. This article reviews the effects of hormonal events on migraine and summarizes the evidence-based options available for management. Estrogen "withdrawal" during the late luteal phase of the natural menstrual cycle and the hormone-free interval of combined hormonal contraceptives has long been implicated in the pathophysiology of menstrual migraine. However, more recent research suggests that other independent mechanisms may be relevant. Prostaglandin inhibitors used for management of dysmenorrhea are effective for associated menstrual migraine, suggesting a common pathophysiology. The interplay between serotonin and estrogen also deserves further research. Menstrual and perimenopausal migraine can be managed effectively using a variety of strategies, the choice of which depends on the efficacy of acute treatment, predictability and regularity of menstruation, use of contraception, and presence of menstrual disorders or perimenopausal vasomotor symptoms.

[Artificial cycle therapy of acupuncture and moxibustion for irregular menstruation].

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Wu, Jie; Yang, Lijie; Chen, Yajie; Li, Qing; Chen, Lin

2015-03-01

Through the discussion on TCM physiological characters of females in follicular, ovulatory, luteal and menstrual phases and treatment principles, the clinical application of artificial cycle therapy of acupuncture and moxibustion was introduced for irregular menstruation and the typical cases were attached. It is suggested that the menstrual cycle follows the growth-consumption rule of yin, yang, qi and blood. The corresponding treatment principles should be applied in accordance with the change rule of menstrual cycle. Hence, it is worth to adopt the artificial cycle therapy of acupuncture and moxibustion for irregular menstruation in clinical application.

Pubescent male students' attitudes towards menstruation in Taiwan: implications for reproductive health education and school nursing practice.

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Chang, Yu-Ting; Hayter, Mark; Lin, Mei-Ling

2012-02-01

To explore male students' attitudes towards menstruation. Menstruation is a biological event that is often surrounded by secrecy and social stigma that causes anxiety amongst many young girls. A key element of this is the attitudes of young males towards this reproductive health issue. However, the literature around what young males think and feel about menstruation is limited. Qualitative. A sample of 27 male students aged between 10-12 years participated in five focus groups. Data were then subject to a thematic analysis. Five themes emerged from the data analysis that reflected the boys' feelings, experiences and attitudes towards menstruation: 'A silent topic', 'An unimportant issue', 'Errant information about menstruation'. In addition, according to their experience, participants gradually came to see menstruation from the 'menstrual stereotype' viewpoint. In their social life, they made choices that resulted in gradually regulating their behaviour that affected their 'relationships with girls'. Young boys have misguided knowledge about menstruation and this helps to perpetuate the stigma surrounding this element of reproductive health. Boys also express a desire to learn more but are often restricted in this by home and school. School nurses are the best placed professionals to address this issue. Menstrual education with boys should take a greater prominence than it often does in sexual health education in schools. Such inclusion will provide boys with a balanced and accurate knowledge base and therefore help towards reducing the social stigma around menstruation that is often experienced by young girls. © 2011 Blackwell Publishing Ltd.

Sociocultural attitudes surrounding menstruation and alternative menstrual products: the explanatory role of self-objectification.

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Grose, Rose Grace; Grabe, Shelly

2014-01-01

We extend objectification theory research to consider the relationship between self-objectification and attitudes toward an alternative menstrual product in a diverse sample of female undergraduates from the United States (N = 151). We use a survey design to investigate attitudes toward one's menstruation as a potential mechanism that may explain this relationship. Reactions to an alternative menstrual product were predominantly negative, supporting prior research on stigma and shame surrounding menstruation. Exploratory structural equation modeling revealed attitudes toward one's menstruation mediated the relationship between self-objectification and participants' reactions to an alternative menstrual product. Implications for women's health are discussed.

Adolescence, Advertising, and the Ideology of Menstruation.

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Merskin, Debra

1999-01-01

Conducted a content analysis of 10 years of feminine hygiene advertisements in "Seventeen" and "Teen" magazines. Finds that advertising copy in these magazines works to dispel myths about menstruation but that few black models are shown. Discusses advertising as an element of socialization for adolescent girls. (SLD)

Menstruation, menstrual protection and menstrual cycle problems. The knowledge, attitudes and practices of young Australian women.

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Abraham, S; Fraser, I; Gebski, V; Knight, C; Llewellyn-Jones, D; Mira, M; McNeil, D

1985-02-18

The results of a survey of 1377 young Australian women aged 14 to 19 years, conducted to determine their attitudes, state of knowledge and practices with regard to menstruation, are presented. The young women, as a group, lacked sufficient information about menstruation, about the time of ovulation, about menstrual discharge, and about the use of tampons. A high proportion (80%) considered menstruation to be inconvenient or embarrassing. Certain measures aimed at remedial action are suggested.

The Level of Testosterone, Vitamin D, and Irregular Menstruation More Important than Omega-3 in Non-Symptomatic Women Will Define the Fate of Multiple Scleroses in Future.

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Tavakol, Shima; Shakibapour, Sahar; Bidgoli, Sepideh Arbabi

2018-01-01

Multiple sclerosis is one of the most salient degenerative disorders of CNS with dysregulated immune process that resulted in axonal damage and demyelination. In the present investigation, the serum level of testosterone was assessed in women who were struggling with multiple sclerosis (MS). Also, the level of omega-3, vitamin D, and the irregular menstruation in women 5 years before the onset MS symptoms were surveyed. Although the levels of omega-3 and vitamin D in women MS patients were non-significant and significantly less than the healthy ones, they were significantly less in the whole population of MS patients. However, the MS patients more experienced more irregular menstruation some years before the onset of MS with the low level of testosterone. Based on the presented findings, it might be said that the vitamin D intake has significant protective role in women and men MS patients unlike the omega-3 that had significant protective role just in men. However, vitamin D metabolism encoding genes of CYP27B1 and CYP24A1 and predicting MS risk gene of HLA-DRB1*15:01 define its fate as well. Besides, vitamin D intake, through the proliferation decrement of pro-inflammatory cells, decreases of pro-inflammatory markers (IL-6, TNF-α, INF-γ) and auto-immune pathways have potential role in recovery of irregular menstruation in women with the low level of testosterone as a red warning factor of MS development. The low level of testosterone and vitamin D consumption increase the neural damage and pro-inflammatory pathways in MS patients, and the difference among the investigations is related to the long-standing history of MS that influences severity of damage to the neural cells and biomolecules and complicate its recovery.

Doing Harm in the Name of Protection: Menstruation as a Topic for Sex Education.

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Diorio, Joseph A.; Munro, Jennifer A.

2000-01-01

Pubertal changes in girls and boys are treated differently in New Zealand schools. Girls learn about menstruation in a scientific, bleak manner, getting an unrealistic picture of growing up. Boys receive positive information about exciting, powerful bodily changes. By protecting girls from problems associated with menstruation, schools risk…

Relation of supplementary feeding to resumptions of menstruation and ovulation in lactating postpartum women.

Science.gov (United States)

Li, Wei; Qiu, Yi

2007-05-20

Resumption of menstrual cycles is one of the indicators for restoration of reproductive capability in postpartum women. However, menstruation does not necessarily mean that ovulation has taken place. The aim of this study was to investigate the relation of supplementary feeding to return of menstruation and ovulation after delivery. A questionnaire was used to obtain data from 101 breastfeeding mothers. The following elements were analyzed: age, education level, breastfeeding practice, time of return of menstruation, contraceptive practice, and starting time of supplementary feeding during the lactation at intervals of 6 weeks to 18 months after delivery. The ovulation was continuously monitored by ultrasonography and basal body temperature (BBT) measurement. By ultrasonography, 53 of the 101 women (52.5%) had the first ovulation (follicle > 1.8 cm in diameter) within 154 days after delivery on average, among whom 11 (10.9%, 11/101) had restoration of ovulation within 4 months and 42 (41.6%, 42/101) had it after 4 months. In women with follicles > 1.8 cm in diameter (n = 53), the menstruation resumed (138 +/- 84) days after delivery, and the supplementary feeding was started at (4.0 +/- 1.1) months, which were significantly earlier than those in the women with follicular diameter menstruation before the end of ultrasonographic monitoring, while only 8 in the women with follicular diameter menstruation (n = 100, r = 0.4764, P < 0.01) and first ovulation after delivery (n = 53, r = 0.5554, P < 0.01). In this series, no woman had pregnancy within 18 months postpartum. Supplementary feeding can affect the restoration of menstrual cycles and ovulation in lactating postpartum women.

More than Just a Punctuation Mark: How Boys and Young Men Learn about Menstruation

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Allen, Katherine R.; Kaestle, Christine E.; Goldberg, Abbie E.

2011-01-01

Parents, peers, schools, and the media are the primary contexts for educating young people about sexuality. Yet girls receive more sex education than boys, particularly in terms of menstruation. Lack of attention to how and what boys learn about menstruation has consequences for their private understanding about the biology of reproduction and…

Use of Oral Contraceptives to Manipulate Menstruation in Young, Physically Active Women.

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Schaumberg, Mia A; Emmerton, Lynne M; Jenkins, David G; Burton, Nicola W; Janse de Jonge, Xanne A K; Skinner, Tina L

2018-01-01

Menstruation and menstrual symptoms are commonly cited barriers to physical activity in women. The delay or avoidance of menstruation through extended oral-contraceptive (OC) regimens may mitigate these barriers, yet information on menstrual-manipulation practices in young physically active women is sparse. The objective of this study was to investigate prevalence of, and reasons for, menstrual manipulation with OCs in recreationally and competitively active women. One hundred ninety-one recreationally active (self-reported moderate to vigorous physical activity 150-300 min/wk) women (age 23 ± 5 y), 160 subelite recreationally active (self-reported moderate to vigorous physical activity >300 min/wk) women (age 23 ± 5 y), and 108 competitive (state-, national- or international-level) female athletes (age 23 ± 4 y) completed a self-administered questionnaire assessing OC-regimen habits and reasons for manipulation of menstruation. The majority (74%) of OC users reported having deliberately manipulated menstruation at least once during the previous year, with 29% reporting having done so at least 4 times. Prevalence of menstrual manipulation (at least once in the previous year) was not different between competitive athletes, subelite recreationally active women, and recreationally active women (77% vs 74% vs 72%; P > .05). The most cited reasons for manipulating menstruation were special events or holidays (rated by 75% as important/very important), convenience (54%), and sport competition (54%). Menstrual manipulation through extended OC regimens is common practice in recreationally and competitively active young women, for a range of reasons relating to convenience that are not limited to physical activity. This strategy may help reduce hormone-related barriers to exercise participation, thereby positively affecting participation and performance.

An Exploration of Issues around Menstruation for Women with Down Syndrome and Their Carers

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Mason, Linda; Cunningham, Cliff

2008-01-01

Background: There is little research on issues related to menstruation for women with Down syndrome, yet they may experience menstruation in a qualitatively different way from normal women, which impacts on their quality of life and that of their families and carers. The aim of this qualitative study was to explore issues with the women and/or…

Young Japanese college students with dysmenorrhea have high frequency of irregular menstruation and premenstrual symptoms.

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Fujiwara, Tomoko; Nakata, Rieko

2007-01-01

In this study, to estimate the current status of young women with menstrual disorders, the relation among dysmenorrhea, irregular menstruation and premenstrual symptoms was investigated by a questionnaire. Subjects ranging from 18 to 20 years old were recruited from 522 female students at Ashiya College in Japan. The intensity of dysmenorrhea was classified into 3 grades (score 1, not requiring analgesic; score 2, painful, requiring analgesic; score 3, painful, not relieved by analgesic). All participants were further divided into subsequent groups as having premenstrual symptoms or not and those having regular or irregular menstruation. Dysmenorrhea scores in the students with premenstrual symptoms or irregular menstruation were significantly higher than those without these symptoms (1.66+/-0.66 vs 1.41+/-0.59; 1.62+/-0.68 vs 1.49+/-0.61, respectively). There was no significant relation in the incidence between premenstrual symptoms and irregular menstruation. These findings suggest that considerable numbers of young women with dysmenorrhea are associated with premenstrual symptoms.

Water, Sanitation and Hygiene Conditions in Kenyan Rural Schools: Are Schools Meeting the Needs of Menstruating Girls?

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Kelly T. Alexander

2014-05-01

Full Text Available Water, sanitation and hygiene (WASH programs in African schools have received increased attention, particularly around the potential impact of poor menstrual hygiene management (MHM on equity for girls’ education. This study was conducted prior to a menstrual feasibility study in rural Kenya, to examine current WASH in primary schools and the resources available for menstruating schoolgirls. Cross-sectional surveys were performed in 62 primary schools during unannounced visits. Of these, 60% had handwashing water, 13% had washing water in latrines for menstruating girls, and 2% had soap. Latrines were structurally sound and 16% were clean. Most schools (84% had separate latrines for girls, but the majority (77% had no lock. Non-governmental organizations (NGOs supported WASH in 76% of schools. Schools receiving WASH interventions were more likely to have: cleaner latrines (Risk Ratio (RR 1.5; 95% Confidence Intervals [CI] 1.0, 2.1, handwashing facilities (RR 1.6, CI 1.1, 2.5, handwashing water (RR 2.7; CI 1.4, 5.2, and water in girls’ latrines (RR 4.0; CI 1.4, 11.6. Schools continue to lack essential WASH facilities for menstruating girls. While external support for school WASH interventions improved MHM quality, the impact of these contributions remains insufficient. Further support is required to meet international recommendations for healthy, gender-equitable schools.

Becoming a Woman: Considerations in Educating Adolescents about Menstruation. Revised 1988. Working Paper No. 169.

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Stubbs, Margaret L.; And Others

This paper reports findings that have emerged from several studies conducted concerning young girls' and boys' attitudes toward menstruation. The research work discussed included: (1) cross-sectional data about menarcheal experience and about attitudes toward menstruation from early adolescent girls in grades six through nine; (2) cross-sectional…

[Successful surgical treatment for catamenial pneumothorax at the time of menstruation].

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Kita, Hidefumi; Shiraishi, Yuji; Katsuragi, Naoya; Shimoda, Kiyomi; Saitou, Miyako

2013-11-01

A 39-year-old female was referred to our hospital due to repeated right pneumothorax. Each episode was related to the onset of menstruation, suggesting catamenial pneumothorax. Thoracoscopy showed multiple blue berry spots on the diaphragm. Partial resection of the diaphragm including these lesions were performed. But she had a recurrent right pneumothorax. Treatment with a gonadotropin-releasing hormone analogue was started, resulting in failure to introduce menopose and the pneumothorax repeatedly appeared again. Reoperation was intentionally done at the time of menstruation enable to find the lesion. Patient is free from pneumothorax more than 6 years after surgery.

Improving pre- and postmenarcheal 12-year-old girls' attitudes toward menstruation.

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Rembeck, Gun I; Gunnarsson, Ronny K

2004-08-01

Adolescence is a time of rapid changes, including risk for unwanted pregnancies and sexually transmitted infections. Education may improve understanding and attitudes toward menstruation among adolescents thus increasing their awareness of risks and enabling them to protect themselves accordingly. To investigate effects of education on attitudes, two interventions were compared in 345 12-year-old girls. The new, active intervention given to premenarcheal girls just before menarche resulted in improvements in attitudes toward menstruation compared with standard intervention. Thus, just before menarche girls should be offered education modeled after the active intervention. The education must be concrete and based on multisensory learning.

Teaching More than the Facts of Menstruation: Exercises to Stimulate Dialogue about a Taboo Subject.

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Taylor, Christina J.

1981-01-01

Presents nine exercises designed to help students and teachers become more aware of their attitudes about menstruation and to move beyond the realms of mystery, ignorance, and taboos. Participants list and analyze expressions used to refer to menstruation, discuss pleasant and unpleasant experiences, and recall feelings on first learning of…

Endometrial adenocarcinoma arising in a Turner's syndrome patient with spontaneous menstruation: a case report.

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Sasamoto, Naoko; Ueda, Yutaka; Amemiya, Kyoka; Enomoto, Takayuki; Morii, Eiichi; Adachi, Kazushige

2014-01-01

Women with Turner's syndrome exhibit anovulation, and the majority do not spontaneously menstruate. We present an unusual case of endometrial adenocarcinoma developing in a Turner's syndrome patient who was exhibiting spontaneous menstruation while not receiving regular hormone therapy. The patient's karyotype from blood lymphocytes was a mosaic of 45,XO/ 46,XX. Menarche and sexual development were normal. Her menstrual cycle had been regular for one year, but then became noticeably irregular. At age 26 she was referred to our hospital after bleeding for almost 1 year. An endometrial adenocarcinoma was detected during performance of diagnostic endometrial curettage. A total abdominal hysterectomy with bilateral salpingo-oophorectomy and pelvic lymphadenectomy was conducted. The final histological diagnosis was endometrial adenocarcinoma, Grade 1, pT1a N0 M0. Fluorescence in situ hybridization analysis of the right and left ovaries revealed a mosaic karyotype of 45,XO/ CONCLUSION: Previous reports regarding Turner's syndrome detected spontaneous menstruation in only 16% of patients; however, spontaneous menstruation was observed in 8 of 10 (80%) Turner's syndrome cases that developed endometrial carcinoma without receiving regular hormone therapy (p < 0.0001). Hormone therapy may be indicated for an irregular menstrual cycle in Turner's syndrome patients.

Role of menstruation in contraceptive choice among HIV-infected women in Soweto, South Africa.

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Laher, Fatima; Todd, Catherine S; Stibich, Mark A; Phofa, Rebecca; Behane, Xoliswa; Mohapi, Lerato; Martinson, Neil; Gray, Glenda

2010-06-01

Contraceptive preferences of HIV-infected women must be considered in efforts to integrate HIV and reproductive health services. In South Africa, contraception is often discontinued due to bleeding pattern changes. It is unknown whether HIV-infected women are more sensitive to menstrual changes and how this affects contraceptive choice. This study describes perceptions toward menses and contraceptive-induced amenorrhea among HIV-infected women. A convenience sample of 42 HIV-infected women aged 15 to 45 years was purposively recruited for three focus groups and 15 in-depth qualitative interviews which were conducted at the Perinatal HIV Research Unit, South Africa. Transcripts were coded and emergent themes grouped. One third of women reported HIV-related menstrual changes, unchanged by antiretroviral use. Menstruation was believed to purge the body of "dirty blood." Women perceived that menstruation had a negative effect on male partner sexual desire, with concern about higher HIV transmission during menstruation. Ninety-six percent of injectable contraceptive users experienced amenorrhea, regarded as troublesome and a reason for discontinuation. In Soweto, HIV diagnosis may accentuate linking menstruation with health, leading to avoidance or discontinuation of methods causing amenorrhea. Providers should intensify education on the safety of contraceptive-induced oligo/amenorrhea.

Premenstrual syndrome and attitudes toward menstruation in a sample of nursing students.

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Guvenc, Gulten; Kilic, Ayse; Akyuz, Aygul; Ustunsoz, Ayfer

2012-09-01

The aim of this study was to evaluate baccalaureate nursing students' attitudes toward menstruation, and to analyze the frequency of premenstrual syndrome (PMS) symptoms, as well as the relationship between attitudes toward menstruation and PMS symptoms. This cross-sectional study was carried out between February 15 and March 10, 2009, in Ankara Turkey. The study participants were 250 undergraduate nursing student volunteers. Data were collected using a demographic questionnaire, the validated Turkish version of the Menstrual Attitude Questionnaire (MAQ), and the validated Turkish Premenstrual Syndrome (PMS) Scale. Obtained data were analyzed using SPSS version 15.0. The average age of participants was 19.89 ± 1.43. The MAQ's five subscales' mean scores ranged from 2.67 ± 0.58 to 3.37 ± 0.52, indicating natural to moderate attitudes toward menstruation. The mean PMS score was 114.86 ± 35.15, indicating moderate PMS symptoms. PMS symptoms were detected in 36.4% of the nursing students. Thirty one percent of the students reported having dysmenorrhoea during every menstrual cycle. Students who had PMS symptoms scored significantly higher on the debilitation subscale and scored significantly lower on the denial subscale of the MAQ (p menstruation was considered to be a natural event by most of the nursing students. In addition, dysmenorrhea was found to be the most common menstrual problem and the rate of PMS was found lower than that found in previous researches conducted in Turkey.

Clinical significance of neonatal menstruation.

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Brosens, Ivo; Benagiano, Giuseppe

2016-01-01

Past studies have clearly shown the existence of a spectrum of endometrial progesterone responses in neonatal endometrium, varying from proliferation to full decidualization with menstrual-like shedding. The bleedings represent, similar to what occurs in adult menstruation, a progesterone withdrawal bleeding. Today, the bleeding is completely neglected and considered an uneventful episode of no clinical significance. Yet clinical studies have linked the risk of bleeding to a series of events indicating fetal distress. The potential link between the progesterone response and major adolescent disorders requires to be investigated by prospective studies. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Cultural perceptions and practices around menarche and adolescent menstruation in the United States.

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Stubbs, Margaret L

2008-01-01

This overview details the persistence of negative characterizations of the menstrual cycle as a feature of the current cultural context in which girls begin menstrual life in the United States. In addition, research on girls' current menstrual attitudes and experiences within this context are reviewed. Current research suggests that girls are not very knowledgeable about menstruation, and that menstrual education continues to provide girls with mixed messages, such as: menstruation is a normal, natural event, but it should be hidden. Girls' attitudes and expectations about menstruation are negatively biased and have been found to contribute to self-objectification, body shame, and lack of agency in sexual decision-making. Although preparation has been found to be associated with more positive menarcheal and menstrual experiences, specificity about what constitutes "good" preparation has not been well articulated. Implications for promoting the menstrual cycle among young girls as a vital sign in service of monitoring their health are discussed.

Menstruation in Rural Igbo Women of South East Nigeria: Attitudes ...

African Journals Online (AJOL)

Menstruation in Rural Igbo Women of South East Nigeria: Attitudes, Beliefs and Practices. ... African Journal of Reproductive Health ... Some respondents observed self-imposed restrictions on exercises, food items, visits and sex in order to ...

Does Menstruation Explain Gender Gaps in Work Absenteeism?

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Herrmann, Mariesa A.; Rockoff, Jonah E.

2012-01-01

Ichino and Moretti (2009) find that menstruation may contribute to gender gaps in absenteeism and earnings, based on evidence that absences of young female Italian bank employees follow a 28-day cycle. We find this evidence is not robust to the correction of coding errors or small changes in specification, and we find no evidence of increased…

Determinants of pre-menarcheal knowledge of menstruation and sociocultural implications in college going girls: A community-based cross-sectional study from Latur, Maharashtra

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Namrata Arvind Thakur

2016-01-01

Full Text Available Introduction: Adolescence marks the onset of female puberty. The first menstruation is often horrifying and traumatic to an adolescent girl because it usually occurs without her knowing about it. Implications of a girl′s response to menarche have a socio-cultural and religious significance. Aim and Objective: To study the sociocultural and physiological implications of menstruation in college going girls. Materials and Methods: This was a community-based cross-sectional observational study undertaken among college girls. All the girls (n = 252 of the college were enrolled in the study. A structured questionnaire was used as the study tool. The questionnaire included topics related to sociodemographic information, sociocultural implications and first informant about the physiological process of menstruation along with its timing. Results: Majority of the study subjects (77.40% observed restrictions for religious/holy things. Sleep disturbances were the most common (59% disturbance faced by the study subjects. Of a total of 252 respondents, majority [104 (41.30%] had leg cramps. The first informant of menstruation was the mother in 196 (77.78% girls. Of 252 girls, 86 (34.12% had pre-menarcheal knowledge of menstruation. Mothers from the urban area and with better education tend to give knowledge of menstruation prior to menarche of her daughter. An increasing trend was observed with increasing educational status of the mother and proportion of them giving pre-menarcheal knowledge of menstruation to their daughter. Conclusions: Menstruation is associated with a high burden of sociocultural implications. Pre-menarcheal knowledge of menstruation is poor. Mothers from the urban area and with better educational level tend to give knowledge of menstruation prior to menarche of their daughter.

Cultural interpretation of menstruation in relation to adolescent girls ...

African Journals Online (AJOL)

Information derived from researching cultural information on menstruation and other forms of blood flow in adolescent girls in Nigeria can contribute extensively to existing knowledge about the female world in general and on adolescent girls in particular. This will further encourage ongoing advocacy programmes in ...

Primary spontaneous pneumothorax in menstruating females has high recurrence

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Mehta, Christopher K.; Stanifer, Bryan P.; Fore-Kosterski, Susan; Gillespie, Colin; Yeldandi, Anjana; Meyerson, Shari; Odell, David D.; DeCamp, Malcolm M.; Bharat, Ankit

2016-01-01

Background Primary spontaneous pneumothorax (PSP) is treated based on studies that have predominantly consisted of tall male subjects. Here we determined recurrence of PSP in average-statured menstruating women and studied prevalence of catamenial pneumothorax (CP) in this population. Methods Males and menstruating females, aged 18-55 years, without underlying lung disease or substance abuse were retrospectively studied between 2009-2015. A chest pathologist reviewed all specimens for thoracic endometriosis. Kaplan-Meier curves were constructed to determine recurrence. Results The median age of females (n=33) and males (n=183) was 33.4 and 31.6 years, respectively. In females, nine (27%) had left-sided and 24 (73%) had right-sided PSP, treated with tube thoracostomy. Recurrence occurred in 21 (64%) females with median follow up of 14 months and was treated with thoracoscopic pleurodesis. Right PSP had higher recurrence (70%) compared to left (56%, p=0.02). Four females (12%) presented with recurrent tension pneumothorax within six months. Eight (24%) patients had PSP within 72 hours of menses, meeting clinical criteria of CP. All these were placed on hormonal suppression after initial episode but went on to develop recurrence that was treated with pleurodesis. However, classic endometrial glands were not found in any biopsy specimens obtained during the thoracoscopy. In contrast to female subjects, only 8 (4.4%) average-statured males had recurrence (p<0.001) with a median follow up of 16 months. Conclusions PSP in healthy average-statured menstruating women has high recurrence compared to male counterparts. CP is a clinical diagnosis and often recurs despite hormonal suppression therapy. PMID:27345097

Leukocyte changes across menstruation, ovulation, and mid-luteal phase and association with sex hormone variation.

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Nowak, Judyta; Borkowska, Barbara; Pawlowski, Boguslaw

2016-09-10

Total leukocyte count (white blood cells-WBC) and the count of each subpopulation vary across the menstrual cycle, but results of studies examining the time and direction of these changes are inconsistent and methodologically flawed. Besides, no previous study focused on leukocyte count on the day of ovulation. Blood samples were obtained from 37 healthy and regularly cycling women aged 19.8-36.1 years. Samples were taken three times: during menstruation (M), ovulation (O), and in the mid-luteal phase (ML). WBC, neutrophils, lymphocytes, mixed cells, progesterone (P,) and estradiol (E) were measured in each of the three target phases of the cycle. Compared to menstruation, WBC (P = 0.002) and neutrophils (P < 0.001) increased around ovulation and remained stable in the mid-luteal phase, whereas lymphocyte and mixed cell counts did not change throughout the menstrual cycle. There were some correlations of sex hormone variation with leukocyte changes between M and O (positive for E and WBC, negative for P and WBC and for P and neutrophil count; P < 0.05), but not between O and ML. Peripheral leukocyte changes taking place in the second half of the cycle are already observable on the day of ovulation and they are associated with sex hormone variation. We speculate that these changes may lead to increased immune protection against pathogens at a time when fertilization and implantation typically occur. Am. J. Hum. Biol. 28:721-728, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Four variants in transferrin and HFE genes as potential markers of iron deficiency anaemia risk: an association study in menstruating women

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Arroyo-Pardo Eduardo

2011-10-01

Full Text Available Abstract Background Iron deficiency anaemia is a worldwide health problem in which environmental, physiologic and genetic factors play important roles. The associations between iron status biomarkers and single nucleotide polymorphisms (SNPs known to be related to iron metabolism were studied in menstruating women. Methods A group of 270 Caucasian menstruating women, a population group at risk of iron deficiency anaemia, participated in the study. Haematological and biochemical parameters were analysed and 10 selected SNPs were genotyped by minisequencing assay. The associations between genetic and biochemical data were analysed by Bayesian Model Averaging (BMA test and decision trees. Dietary intake of a representative subgroup of these volunteers (n = 141 was assessed, and the relationship between nutrients and iron biomarkers was also determined by linear regression. Results Four variants, two in the transferrin gene (rs3811647, rs1799852 and two in the HFE gene (C282Y, H63D, explain 35% of the genetic variation or heritability of serum transferrin in menstruating women. The minor allele of rs3811647 was associated with higher serum transferrin levels and lower transferrin saturation, while the minor alleles of rs1799852 and the C282Y and H63D mutations of HFE were associated with lower serum transferrin levels. No association between nutrient intake and iron biomarkers was found. Conclusions In contrast to dietary intake, these four SNPs are strongly associated with serum transferrin. Carriers of the minor allele of rs3811647 present a reduction in iron transport to tissues, which might indicate higher iron deficiency anaemia risk, although the simultaneous presence of the minor allele of rs1799852 and HFE mutations appear to have compensatory effects. Therefore, it is suggested that these genetic variants might potentially be used as markers of iron deficiency anaemia risk.

Associations of Age, BMI, and Years of Menstruation with Proximal Femur Strength in Chinese Postmenopausal Women: A Cross-Sectional Study.

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Kang, Huili; Chen, Yu-Ming; Han, Guiyuan; Huang, Hua; Chen, Wei-Qing; Wang, Xidan; Zhu, Ying-Ying; Xiao, Su-Mei

2016-01-23

This study aimed to elucidate the associations of age, BMI, and years of menstruation with proximal femur strength in Chinese postmenopausal women, which may improve the prediction of hip fracture risk. A cross-sectional study was conducted in 1322 Chinese postmenopausal women recruited from communities. DXA images were used to generate bone mineral density (BMD) and geometric parameters, including cross-sectional area (CSA), outer diameter (OD), cortical thickness (CT), section modulus (SM), buckling ratio (BR) at the narrow neck (NN), intertrochanter (IT), and femoral shaft (FS). Relationships of age, BMI, and years of menstruation with bone phenotypes were analyzed with the adjustment of height, age at menarche, total daily physical activity, education, smoking status, calcium tablet intake, etc. Age was associated with lower BMD, CSA, CT, SM, and higher BR (p menstruation had the positive relationships with proximal femur strength (p menstruation were 0.14%-1.34%, 0.20%-2.70%, and 0.16%-0.98%, respectively. These results supported that bone strength deteriorated with aging and enhanced with higher BMI and longer time of years of menstruation in Chinese postmenopausal women.

Primary Spontaneous Pneumothorax in Menstruating Women Has High Recurrence.

Science.gov (United States)

Mehta, Christopher K; Stanifer, Bryan P; Fore-Kosterski, Susan; Gillespie, Colin; Yeldandi, Anjana; Meyerson, Shari; Odell, David D; DeCamp, Malcolm M; Bharat, Ankit

2016-10-01

Primary spontaneous pneumothorax (PSP) is treated on the basis of studies that have predominantly consisted of tall male subjects. Here, we determined recurrence of PSP in average-statured menstruating women and studied prevalence of catamenial pneumothorax (CP) in this population. Men and menstruating women, aged 18 to 55 years, without underlying lung disease or substance abuse were retrospectively studied between 2009 and 2015. A chest pathologist reviewed all specimens for thoracic endometriosis. Kaplan-Meier curves were constructed to determine recurrence. The median age of women (n = 33) and men (n = 183) was 33.4 and 31.6 years, respectively. In women, 9 (27%) had left-sided and 24 (73%) had right-sided PSP, treated with tube thoracostomy. Recurrence occurred in 21 women (64%) with median follow-up of 14 months, and they were treated with thoracoscopic pleurodesis. Right PSP had higher recurrence (70%) than left PSP (56%, p = 0.02). Four women (12%) presented with recurrent tension pneumothorax within 6 months. Eight patients (24%) had PSP within 72 hours of menses, meeting clinical criteria of CP. All these were placed on hormonal suppression after initial episode but went on to experience recurrence that was treated with pleurodesis. Classical endometrial glands were not found in any biopsy specimens obtained during the thoracoscopy. In contrast to female subjects, only 8 average-statured men (4.4%) had recurrence (p < 0.001) with a median follow-up of 16 months. PSP in healthy average-statured menstruating women has high recurrence compared with male counterparts. CP is a clinical diagnosis and often recurs despite hormonal suppression therapy. Copyright © 2016 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

Imagery Associated with Menstruation in Advertising Targeted to Adolescent Women.

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Havens, Beverly; Swenson, Ingrid

1988-01-01

Analyzed imagery in advertisements in "Seventeen" magazine for sanitary products and products for relief of menstrual symptoms, looking for recurrent themes in text, context, and tone. Found menstruation depicted as a "hygienic crisis" best managed by an effective "security system" affording protection and "peace…

Evaluation of periodic safety status analyses

International Nuclear Information System (INIS)

Faber, C.; Staub, G.

1997-01-01

In order to carry out the evaluation of safety status analyses by the safety assessor within the periodical safety reviews of nuclear power plants safety goal oriented requirements have been formulated together with complementary evaluation criteria. Their application in an inter-disciplinary coopertion covering the subject areas involved facilitates a complete safety goal oriented assessment of the plant status. The procedure is outlined briefly by an example for the safety goal 'reactivity control' for BWRs. (orig.) [de

Students' perceptions and doubts about menstruation in developing countries: a case study from India.

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Chothe, Vikas; Khubchandani, Jagdish; Seabert, Denise; Asalkar, Mahesh; Rakshe, Sarika; Firke, Arti; Midha, Inuka; Simmons, Robert

2014-05-01

Menstrual education is a vital aspect of adolescent health education. Culture, awareness, and socioeconomic status often exert profound influence on menstrual practices. However, health education programs for young women in developing countries do not often address menstrual hygiene, practices, and disorders. Developing culturally sensitive menstrual health education and hygiene programs for adolescent females has been recommended by professional health organizations like the World Health Organization and UNICEF. These programs cannot be developed without understanding existing myths and perceptions about menstruation in adolescent females of developing countries. Thus, the purpose of this qualitative study from India was to document existing misconceptions regarding menstruation and perceptions about menarche and various menstrual restrictions that have been understudied. Out of the 612 students invited to participate by asking questions, 381 girls participated by asking specific questions about menstruation (response rate = 62%). The respondents consisted of 84 girls from sixth grade, 117 from seventh grade, and 180 from eighth grade. The questions asked were arranged into the following subthemes: anatomy and physiology, menstrual symptoms, menstrual myths and taboos, health and beauty, menstrual abnormalities, seeking medical advice and home remedies; sanitary pads usage and disposal; diet and lifestyle; and sex education. Results of our study indicate that students had substantial doubts about menstruation and were influenced by societal myths and taboos in relation to menstrual practices. Parents, adolescent care providers, and policy makers in developing countries should advocate for comprehensive sexuality education and resources (e.g., low-cost sanitary pads and school facilities) to promote menstrual health and hygiene promotion.

Menstruation and School Absenteeism: Evidence from Rural Malawi

OpenAIRE

Grant, Monica J.; Lloyd, Cynthia B.; Mensch, Barbara S.

2013-01-01

The provision of toilets and menstrual supplies has emerged as a promising programmatic strategy to support adolescent girls’ school attendance and performance in less developed countries. We use the first round of the Malawi Schooling and Adolescent Survey (MSAS) to examine the individual- and school-level factors associated with menstruation-related school absenteeism. The MSAS is a school-based longitudinal survey of adolescent students enrolled in coed public primary schools in the southe...

Spanish women's attitudes towards menstruation and use of a continuous, daily use hormonal combined contraceptive regimen.

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Sánchez-Borrego, Rafael; García-Calvo, Carmen

2008-02-01

The main objective of this survey was to explore the attitude of Spanish women towards menstruation, as well as their acceptability of a daily, continuous, combination oral contraceptive regimen. National survey carried out in Spain in 2006. A total of 588 women aged between 18 and 45 years old answered an anonymous questionnaire that included questions regarding menstruation and acceptability of new contraceptive regimens. Overall, 24.5% of women expressed interest in using the continuous oral contraceptive regimen. This percentage increased up to nearly 50% in women younger than 25 years old and those not using any contraceptive method but willing to use them in the future. The attitude of Spanish women towards menstruation observed in this survey seems to be more conservative than that obtained in other recent international surveys. An improvement in the education provided by practitioners would help women to make informed decisions.

Menstruation across time: menarche, menstrual attitudes, experiences, and behaviors.

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McPherson, Marianne E; Korfine, Lauren

2004-01-01

This study explored the relationship between early and current menstrual experiences. The primary hypothesis was that women who reported positive menarcheal experiences (including menstrual education and menarche) would tend to report positive current menstrual attitudes, experiences, and/or behaviors, and vice versa for women who reported negative menarcheal experiences. In this survey-based study, college-aged women (n = 327) were screened by completing a questionnaire concerning their menarcheal experiences. Women who had extremely negative ("negative group," n = 46) or extremely positive ("positive group," n = 38) early menstrual experiences returned to complete questionnaires concerning current menstrual attitudes, experiences, and behaviors. Early and current menstrual experiences were most strongly associated in the domain of menstrual attitudes. Women in the negative group reported more negative menstrual attitudes than did women in the positive group. There were additional associations between early menstrual experiences and measures of body image and health behaviors. Positive group participants reported more positive body image and better general health behaviors. Results suggest that early menstrual experiences may be related to menstrual experiences later in life. This study invites further investigation of the psychology of menstruation and suggests connecting menstruation with other women's health issues.

Teaching Taboo Topics: Menstruation, Menopause, and the Psychology of Women

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Chrisler, Joan C.

2013-01-01

The purpose of this article is (a) to consider reasons why women's reproductive processes receive so little attention in psychology courses and (b) to make an argument for why more attention is needed. Menstruation, menopause, and other reproductive events are important to the psychology of women. Reproductive processes make possible a social role…

Association between menstruation signs and anxiety, depression, and stress in school girls in Mashhad in 2011-2012

OpenAIRE

Mohamadirizi, Soheila; Kordi, Masoumeh

2013-01-01

Background: Menstruation signs are among the most common disorders in adolescents and are influenced by various environmental and psychosocial factors. This study aimed to define the association between menstruation signs and anxiety, depression, and stress in school girls in Mashhad in 2011-2012. Materials and Methods: This was a cross-sectional study on 407 high school girls in Mashhad who were selected through two-step random sampling. The students completed a questionnaire concerning demo...

Menstruation in an unusual place: A case of thoracic endometriosis ...

African Journals Online (AJOL)

While pelvic endometriosis is relatively common, thoracic menstruation is rare. A report of what is believed to be the first case of thoracic endometriosis in Uganda is given. A 34 year old female was complaining of on and off chest pain mainly on the right side. Clinically she had signs of pleural effusion and 500 mls of altered ...

Do lunar phases influence menstruation? A year-long retrospective study.

Science.gov (United States)

Ilias, I; Spanoudi, F; Koukkou, E; Adamopoulos, D A; Nikopoulou, S C

2013-07-01

We assessed with cross-approximate entropy menstruation onset versus moon phases in 74 women with 980 menstrual cycles over a calendar year. In defiance of traditional beliefs and contrary to what some researchers have argued with short-term research work, in this long-term study we did not find any synchrony of lunar phases with the menstrual cycle.

A non-equilibrium neutral model for analysing cultural change.

Science.gov (United States)

Kandler, Anne; Shennan, Stephen

2013-08-07

Neutral evolution is a frequently used model to analyse changes in frequencies of cultural variants over time. Variants are chosen to be copied according to their relative frequency and new variants are introduced by a process of random mutation. Here we present a non-equilibrium neutral model which accounts for temporally varying population sizes and mutation rates and makes it possible to analyse the cultural system under consideration at any point in time. This framework gives an indication whether observed changes in the frequency distributions of a set of cultural variants between two time points are consistent with the random copying hypothesis. We find that the likelihood of the existence of the observed assemblage at the end of the considered time period (expressed by the probability of the observed number of cultural variants present in the population during the whole period under neutral evolution) is a powerful indicator of departures from neutrality. Further, we study the effects of frequency-dependent selection on the evolutionary trajectories and present a case study of change in the decoration of pottery in early Neolithic Central Europe. Based on the framework developed we show that neutral evolution is not an adequate description of the observed changes in frequency. Copyright © 2013 Elsevier Ltd. All rights reserved.

Menstruation and menstrual hygiene amongst adolescent school girls in Kano, Northwestern Nigeria.

Science.gov (United States)

Lawan, U M; Yusuf, Nafisa Wali; Musa, Aisha Bala

2010-09-01

This study examined the knowledge and practices of adolescent school girls in Kano, Nigeria around menstruation and menstrual hygiene. Data was collected quantitatively and analyzed using Epi info version 3.2.05. The mean age of the students was 14.4 +/- 1.2 years; majority was in their mid adolescence. The students attained menarche at 12.9 +/- 0.8 years. Majority had fair knowledge of menstruation, although deficient in specific knowledge areas. Most of them used sanitary pads as absorbent during their last menses; changed menstrual dressings about 1-5 times per day; and three-quarter increased the frequency of bathing. Institutionalizing sexuality education in Nigerian schools; developing and disseminating sensitive adolescent reproductive health massages targeted at both parents and their adolescent children; and improving access of the adolescents to youth friendly services are veritable means of meeting the adolescent reproductive health needs in Nigeria.

A cross-sectional study to assess awareness about menstruation in adolescent girls of an urban slum in western Maharashtra.

Science.gov (United States)

Dudeja, Puja; Sindhu, Apoorva; Shankar, Pooja; Gadekar, Tukaram

2016-10-14

Reproductive health of adolescent girls is crucial as it determines the health of future generations. School girls when experiencing menarche find themselves in a setting without water, toilets or a supportive female teacher to explain the changes happening in their body. An important concern for adolescent girls is to have adequate, correct knowledge along with facilities and the cultural environment to manage menstruation hygienically and with dignity. Hence, the present study was done to assess knowledge and practices about menstruation in adolescent school girls of an urban slum. This was a descriptive cross-sectional study conducted among girls of a Government School located in an urban slum of western Maharashtra. A total of 250 girls participated. Data collection was through a pilot-tested questionnaire. The data thus collected were entered into Microsoft Excel and analyzed using the SPSS 20 software. All girls were educated about menstrual hygiene after the study. The mean age of the students was 14.9±1.75 years. The mean age at menarche was 11.97 (95% CI: 11.94-11.99). It was observed that only half (56.4%) had acquired prior knowledge about attaining menarche. Out of these in a large proportion, the knowledge was imparted to them by their mothers (60.7%), followed by friends (31.8%). There was no significant association between educational status of mother and awareness in respondent about menstruation. Regarding the organ of menstrual blood flow, half (50.7%) knew the correct answer (i.e. uterus); whereas the rest believed that it was stomach/kidney, etc. Most of the school girls (90.5%) used sanitary pads. Almost 90% of the young women faced physical complaints or health problems during menstruation. Most of the participants had some kind of restrictions on them during the menstruation and most of these were religious restrictions (69.7%) followed by physical (41.2%) and social restrictions (22.3%). All of them were unsatisfied with the toilets and

Menarche and menstruation through the eyes of pubescent students in eastern Taiwan: implications in sociocultural influence and gender differences issues.

Science.gov (United States)

Chang, Yu-Ting; Lin, Mei-Ling

2013-03-01

Menstruation is a significant part of women's lives. It has been studied from many perspectives to draw various conclusions about biological and physiological development, gender differences, and sociocultural environments. The purpose of this study was to explore how male and female pubescent students perceive and interpret menarche and menstruation and how their perceptions reflect gender differences and the sociocultural environment in eastern Taiwan. This was an exploratory qualitative study that employed focus group interviews. Data were collected from 20 girls and 27 boys, aged 10-12 years, who were recruited from two elementary schools. Participants engaged in 19 focus group discussions, which lasted 45-60 minutes each. Discussion transcripts were collected, encoded, categorized, and analyzed using the Atlas V 5.0 software. The central theme in menarche and menstruation experiences among pubescent students in eastern Taiwan can be summarized as, "Struggling to grow up amidst contradictions," an attitude that reflects gender divisions and sociocultural representations and practices. Generally, participants' views on menstruation fell within five subthemes: "Ambiguous," "Disregarded," "Dirty," "Personal," and "Transitional." These themes were analyzed within the contexts of society, school, and family. In line with previous research, this study shows the need for more individual reproductive health consultations, reliable sex education, and well-planned health policies to assist pubescent students manage menstruation. In addition, this study suggests that the subjugation of girls and women remains a critical issue that must be addressed and challenged.

Non-linear second-order periodic systems with non-smooth potential

Indian Academy of Sciences (India)

In this paper we study second order non-linear periodic systems driven by the ordinary vector -Laplacian with a non-smooth, locally Lipschitz potential function. Our approach is variational and it is based on the non-smooth critical point theory. We prove existence and multiplicity results under general growth conditions on ...

Non-linear second-order periodic systems with non-smooth potential

Indian Academy of Sciences (India)

R. Narasimhan (Krishtel eMaging) 1461 1996 Oct 15 13:05:22

Abstract. In this paper we study second order non-linear periodic systems driven by the ordinary vector p-Laplacian with a non-smooth, locally Lipschitz potential function. Our approach is variational and it is based on the non-smooth critical point theory. We prove existence and multiplicity results under general growth ...

Influence of menstruation on the microbiota of healthy women's labia minora as analyzed using a 16S rRNA gene-based clone library method.

Science.gov (United States)

Shiraishi, Tsukasa; Fukuda, Kazumasa; Morotomi, Nobuo; Imamura, Yuri; Mishima, Junko; Imai, Shigeo; Miyazawa, Kiyoshi; Taniguchi, Hatsumi

2011-01-01

The aim of this study was to determine the influence of menstruation on the bacterial population of healthy Japanese women's vulvas, especially the labia minora. Labia minora swabs were obtained from 10 premenopausal, nonpregnant Japanese women at premenstruation and on day 2 of menstruation. Vaginal swabs were also obtained from 3 out of the 10 women. No significant difference was found in the average bacterial cell count between the menstruation and premenstruation samples. Molecular analysis using a 16S rRNA gene-based clone library method detected 22 genera from the labia minora swabs (total 20), with the genus Lactobacillus being predominant at both premenstruation and during menstruation in 7 out of the 10 women. Of the other 3 women, 2 showed various kinds of bacterial species, including oral and fecal bacteria, with Atopobium vaginae and Gardnerella vaginalis predominating in the remaining woman's vulva in both conditions. In total, 6 out of 10 cases (60%) showed significantly different microbiota of the labia minora between the two conditions. These results imply that menstruation may promote a distortion of the bacterial flora around the vulva, although it causes no significant increase of the bacterial count.

Comparison of Periodized and Non-Periodized Resistance Training on Maximal Strength: A Meta-Analysis.

Science.gov (United States)

Williams, Tyler D; Tolusso, Danilo V; Fedewa, Michael V; Esco, Michael R

2017-10-01

Periodization is a logical method of organizing training into sequential phases and cyclical time periods in order to increase the potential for achieving specific performance goals while minimizing the potential for overtraining. Periodized resistance training plans are proposed to be superior to non-periodized training plans for enhancing maximal strength. The primary aim of this study was to examine the previous literature comparing periodized resistance training plans to non-periodized resistance training plans and determine a quantitative estimate of effect on maximal strength. All studies included in the meta-analysis met the following inclusion criteria: (1) peer-reviewed publication; (2) published in English; (3) comparison of a periodized resistance training group to a non-periodized resistance training group; (4) maximal strength measured by 1-repetition maximum (1RM) squat, bench press, or leg press. Data were extracted and independently coded by two authors. Random-effects models were used to aggregate a mean effect size (ES), 95% confidence intervals (CIs) and potential moderators. The cumulative results of 81 effects gathered from 18 studies published between 1988 and 2015 indicated that the magnitude of improvement in 1RM following periodized resistance training was greater than non-periodized resistance training (ES = 0.43, 95% CI 0.27-0.58; P training status (β = -0.59; P = 0.0305), study length (β = 0.03; P = 0.0067), and training frequency (β = 0.46; P = 0.0123) were associated with a change in 1RM. These results indicate that undulating programs were more favorable for strength gains. Improvements in 1RM were greater among untrained participants. Additionally, higher training frequency and longer study length were associated with larger improvements in 1RM. These results suggest that periodized resistance training plans have a moderate effect on 1RM compared to non-periodized training plans. Variation in training stimuli

[Menstruation, inflammation and comorbidities: implications for woman health].

Science.gov (United States)

Graziottin, A; Zanello, P P

2015-02-01

Menstruation is the genital sign of systemic endocrine events. Heterogeneity of perimenstrual symptoms is associated with levels of inflammation, triggered by the fall of estrogens at genital and systemic level. Aim of the review is to concisely analyze the evidence on: 1) genital and systemic endocrine and inflammatory events associated with periods and perimenstrual symptoms; 2) rationale of intervention to reduce their intensity and impact on women's lives. This review of the literature, selected with a clinical perspective, supports the inflammatory basis of the menstrual event, triggered by the estrogens' and progesterone' fall. Moreover, the review analyzes the endocrine and inflammatory basis of perimenstrual pelvic and extrapelvic symptoms such as: menstrual pain, menstrual irregularities, premenstrual syndrome, gastrointestinal symptoms, catamenial headache, depression, perimenstrual myalgia, joint pain, allergies and asthma, heavy menstrual bleeding, associated ironless anemia, brain and behavioral consequences. Inflammation, with increase of cytokines and other markers, is modulated by the degranulation of mast cells at the basal level of the endometrium, in the blood, in all the organs where mast-cell are already activated from local pathologies and within the brain. The shift of inflammation from physiological to a pathologic intensity increases the severity of perimenstrual symptoms. Symptoms persist, moderately attenuated, also during the hormone free interval (HFI) in contraception. The HFI reduction from seven to two days significantly reduces menstrual inflammation and associated symptoms.

Granulocytes and vascularization regulate uterine bleeding and tissue remodeling in a mouse menstruation model.

Directory of Open Access Journals (Sweden)

Astrid Menning

Full Text Available Menstruation-associated disorders negatively interfere with the quality of life of many women. However, mechanisms underlying pathogenesis of menstrual disorders remain poorly investigated up to date. Among others, this is based on a lack of appropriate pre-clinical animal models. We here employ a mouse menstruation model induced by priming mice with gonadal hormones and application of a physical stimulus into the uterus followed by progesterone removal. As in women, these events are accompanied by menstrual-like bleeding and tissue remodeling processes, i.e. disintegration of decidualized endometrium, as well as subsequent repair. We demonstrate that the onset of bleeding coincides with strong upregulation of inflammatory mediators and massive granulocyte influx into the uterus. Uterine granulocytes play a central role in regulating local tissue remodeling since depletion of these cells results in dysregulated expression of matrix modifying enzymes. As described here for the first time, uterine blood loss can be quantified by help of tampon-like cotton pads. Using this novel technique, we reveal that blood loss is strongly reduced upon inhibition of endometrial vascularization and thus, is a key regulator of menstrual bleeding. Taken together, we here identify angiogenesis and infiltrating granulocytes as critical determinants of uterine bleeding and tissue remodeling in a mouse menstruation model. Importantly, our study provides a technical and scientific basis allowing quantification of uterine blood loss in mice and thus, assessment of therapeutic intervention, proving great potential for future use in basic research and drug discovery.

Meanings and Experiences of Menstruation: Perceptions of Institutionalized Women with an Intellectual Disability

Science.gov (United States)

Chou, Yueh-Ching; Lu, Zxy-Yann Jane; Wang, Frank T. Y.; Lan, Chang-Fu; Lin, Li-Chan

2008-01-01

Background: No studies have ever been conducted concerning menstrual experiences among women with an intellectual disability in Taiwan. Materials and Methods: An in-depth interview was conducted at three public institutions and perceptions and experiences regarding menstruation were elicited from 55 women aged 21-65 years. Results: The…

Menstruation during and after caloric restriction: the 1944-1945 Dutch famine.

Science.gov (United States)

Elias, Sjoerd G; van Noord, Paulus A H; Peeters, Petra H M; den Tonkelaar, Isolde; Kaaks, Rudolf; Grobbee, Diederick E

2007-10-01

To investigate the relation between exposure to the 1944-45 Dutch famine and concurrent and subsequent menstrual disturbances. Cohort study. Doorlopend Onderzoek Mammacarcinoom breast cancer screening project, Utrecht, the Netherlands. Between 1983 and 1986, approximately 12,500 women (born 1911-41) reported their individual famine experiences. Irregular menstruation during the famine; time to regular menses after menarche, and menstrual patterns in adulthood after childhood famine. The famine had a direct impact on menstruation. The odds ratio (OR) of concurrent irregular menses in severely versus unexposed women was 8.85 (95% confidence interval [CI], 7.31-10.70). Women exposed to severe famine before menarche were 1.51 (95% CI, 1.15-1.98) times more likely to experience irregular menses for a prolonged time after menarche compared with the unexposed. This association was stronger in women with an early menarche. When the menstrual pattern was assessed in adulthood by menstrual diaries, a nonsignificant tendency of increased irregularity (OR, 1.13; 95% CI, 0.82-1.54) and regular but long menstrual cycles (OR, 1.41; 95% CI, 0.89-2.23) was observed in women exposed to severe famine. Famine relates to concurrent menstrual irregularity, and exposure in childhood seems to affect the subsequent menstrual pattern.

Treatment of menorrhagia during menstruation: randomised controlled trial of ethamsylate, mefenamic acid, and tranexamic acid.

Science.gov (United States)

Bonnar, J; Sheppard, B L

1996-09-07

To compare the efficacy and acceptability of ethamsylate, mefenamic acid, and tranexamic acid for treating menorrhagia. Randomised controlled trial. A university department of obstetrics and gynaecology. 76 women with dysfunctional uterine bleeding. Treatment for five days from day 1 of menses during three consecutive menstrual periods. 27 patients were randomised to take ethamsylate 500 mg six hourly, 23 patients to take mefenamic acid 500 mg eight hourly, and 26 patients to take tranexamic acid 1 g six hourly. Menstrual loss measured by the alkaline haematin method in three control menstrual periods and three menstrual periods during treatment; duration of bleeding; patient's estimation of blood loss; sanitary towel usage; the occurrence of dysmenorrhoea; and unwanted events. Ethamsylate did not reduce mean menstrual blood loss whereas mefenamic acid reduced blood loss by 20% (mean blood loss 186 ml before treatment, 148 ml during treatment) and tranexamic acid reduced blood loss by 54% (mean blood loss 164 ml before treatment, 75 ml during treatment). Sanitary towel usage was significantly reduced in patients treated with mefenamic acid and tranexamic acid. Tranexamic acid given during menstruation is a safe and highly effective treatment for excessive bleeding. Patients with dysfunctional uterine bleeding should be offered medical treatment with tranexamic acid before a decision is made about surgery.

Efficacy of peeling during different periods of the menstrual cycle on acne.

Science.gov (United States)

Bulbul Baskan, Emel; Tilki Günay, Işıl; Saricaoglu, Hayriye

2017-10-01

The aim of this study was to investigate the efficacy of 50% glycolic acid peeling performed at different phases of menstruation on acne. This study included 30 patients with mild-to-moderate acne. Those with regular menstrual cycles and no history or laboratory evidence of hormonal pathology, hirsutism were selected. Thirty patients were divided in three groups. The first group received peeling applications in the first 7 days of menstruation; the second group received the peel between 10 and 14 days; and the third group received the peel during the last 10 days of menstruation. The 30 female patients included in study. All patients' menstrual cycles were regular. All groups were homogenous in terms of initial acne severity scores. Acne severity scores decreased in all groups after 3 months of therapy; statistically significant differences were achieved only in the second group. The results of our study suggest that chemical peeling administered during ovulation provides the most significant benefit for acne lesions. Ovulation is the period when estrogen reaches its highest level. Estrogen decreases sebum production through different mechanisms. The beneficial effects of estrogen on acne and healing in combination with those of chemical peeling may cause synergistic therapeutic effects with pronounced results.

Impact of health education on knowledge and practices about menstruation among adolescent school girls of rural part of district Ambala, Haryana

Directory of Open Access Journals (Sweden)

A Arora

2013-12-01

Full Text Available Background: This study was undertaken to assess the impact of health education on knowledge regarding menstruation, misconceptions related to it as the prevalence of RTI is still very high in India.  Aims: To study the existing level of status of hygiene, knowledge and practices regarding menstruation among adolescent school girls and to assess the change in their knowledge level and practices after health education. Materials A community-based pre and post interventional study was conducted among 200 adolescents’ girls of class IX and X of rural part of district Ambala. Multistage random sampling technique was used to draw the representative sample. A pre-tested questionnaire was administered and later health education regarding menstruation and healthy menstrual practices was imparted to the girls. Post-test was done after 3 months to assess the impact of health education. Pre- and post-intervention, data were compared using the paired t test, z test for proportions, chi-squared test for paired proportions. Difference between Proportions of the pre-post data and its 95% confidence interval has been calculated of the findings. SPSS for Windows software version 20 (IBM, Chicago, USA have been used for data analysis. The level of significance has been considered at p value 0.05 while in the post-test preceding health education, significant improvements were observed in their practices. Conclusion: Overall significant improvement was found in knowledge and practices regarding menstruation among adolescent school girls.

'We keep it secret so no one should know'--a qualitative study to explore young schoolgirls attitudes and experiences with menstruation in rural western Kenya.

Science.gov (United States)

Mason, Linda; Nyothach, Elizabeth; Alexander, Kelly; Odhiambo, Frank O; Eleveld, Alie; Vulule, John; Rheingans, Richard; Laserson, Kayla F; Mohammed, Aisha; Phillips-Howard, Penelope A

2013-01-01

Keeping girls in school offers them protection against early marriage, teen pregnancy, and sexual harms, and enhances social and economic equity. Studies report menstruation exacerbates school-drop out and poor attendance, although evidence is sparse. This study qualitatively examines the menstrual experiences of young adolescent schoolgirls. The study was conducted in Siaya County in rural western Kenya. A sample of 120 girls aged 14-16 years took part in 11 focus group discussions, which were analysed thematically. The data gathered were supplemented by information from six FGDs with parents and community members. Emergent themes were: lack of preparation for menarche; maturation and sexual vulnerability; menstruation as an illness; secrecy, fear and shame of leaking; coping with inadequate alternatives; paying for pads with sex; and problems with menstrual hygiene. Girls were unprepared and demonstrated poor reproductive knowledge, but devised practical methods to cope with menstrual difficulties, often alone. Parental and school support of menstrual needs is limited, and information sparse or inaccurate. Girls' physical changes prompt boys and adults to target and brand girls as ripe for sexual activity including coercion and marriage. Girls admitted 'others' rather than themselves were absent from school during menstruation, due to physical symptoms or inadequate sanitary protection. They described difficulties engaging in class, due to fear of smelling and leakage, and subsequent teasing. Sanitary pads were valued but resource and time constraints result in prolonged use causing chafing. Improvised alternatives, including rags and grass, were prone to leak, caused soreness, and were perceived as harmful. Girls reported 'other girls' but not themselves participated in transactional sex to buy pads, and received pads from boyfriends. In the absence of parental and school support, girls cope, sometimes alone, with menarche in practical and sometimes hazardous

'The girl with her period is the one to hang her head' Reflections on menstrual management among schoolgirls in rural Kenya

Directory of Open Access Journals (Sweden)

Obure Alfredo F

2011-06-01

Full Text Available Abstract Background The onset of menstruation is a landmark event in the life of a young woman. Yet the complications and challenges that can accompany such an event have been understudied, specifically in resource-poor settings. As interventions aim to improve female attendance in schools, it is important to explore how menstruation is perceived and navigated by girls in the school setting. This research conveys rural Kenyan schoolgirls' perceptions and practices related to menstruation Methods Data were collected at six rural schools in the Nyanza Province of Western Kenya. Using focus group discussions, in-depth interviews, and field notes from observations, researchers collected information from 48 primary schoolgirls and nine teachers. Systematic analysis began with a reading of transcripts and debriefing notes, followed by manual coding of the narratives. Results Focus group discussions became opportunities for girls to share thoughts on menstruation, instruct one another on management practices and advise one another on coping mechanisms. Girls expressed fear, shame, distraction and confusion as feelings associated with menstruation. These feelings are largely linked to a sense of embarrassment, concerns about being stigmatized by fellow students and, as teachers explained, a perception that the onset of menstruation signals the advent of a girl's sexual status. Among the many methods for managing their periods, girls most frequently said they folded, bunched up or sewed cloth, including cloth from shirts or dresses, scraps of old cloth, or strips of an old blanket. Cloth was reported to frequently leak and cause chafing, which made school attendance difficult particularly as the day progressed. Attitudes and practices of girls toward menstruation have been arranged into personal, environmental and behavioural factors. Conclusion Further research on menstrual management options that are practical, sustainable and culturally acceptable

Prognostic Effects of Adjuvant Chemotherapy-Induced Amenorrhea and Subsequent Resumption of Menstruation for Premenopausal Breast Cancer Patients

Science.gov (United States)

Jeon, Se Jeong; Lee, Jae Il; Jeon, Myung Jae; Lee, Maria

2016-01-01

Abstract Chemotherapy-induced amenorrhea (CIA) is a side effect that occurs in patients with breast cancer (BC) as a result of chemotherapy. These patients require special treatments to avoid infertility and menopause. However, the factors controlling CIA, resumption of menstruation (RM), and persistence of menstruation after chemotherapy are unknown. The long-term prognosis for premenopausal patients with BC and the prognostic factors associated with CIA and RM are subject to debate. We performed a retrospective study by reviewing the medical records of 249 patients with BC (stage I to stage III) who were treated with cytotoxic chemotherapy. The median patient age was 43 (range, 26–55 years) and the median duration of follow-up was 64 months (range, 28–100 months). The medical records indicated that 219 patients (88.0%) scored as positive for the hormone receptor (HR); the majority of these patients completed chemotherapy and then received additional therapy of tamoxifen. Our analyses revealed that 88.0% (n = 219) of patients experienced CIA, and the percentage of RM during follow-up was 48.6% (n = 121). A total of 30 patients (12.0%) did not experience CIA. Disease-free survival (DFS) was affected by several factors, including tumour size ≥2 cm, node positivity, HR negative status, and body mass index ≥23 kg/m2. Multivariate analysis indicated that tumour size ≥2 cm remained as a significant factor for DFS (hazard ratio = 3.3, P = 0.034). In summary, this study finds that the majority of premenopausal patients with BC (stage I to stage III) who receive chemotherapy experience CIA and subsequent RM. Although tumour size ≥2 cm is negatively associated with DFS, RM after CIA is not associated with poor prognosis. PMID:27057900

Prognostic Effects of Adjuvant Chemotherapy-Induced Amenorrhea and Subsequent Resumption of Menstruation for Premenopausal Breast Cancer Patients.

Science.gov (United States)

Jeon, Se Jeong; Lee, Jae Il; Jeon, Myung Jae; Lee, Maria

2016-04-01

Chemotherapy-induced amenorrhea (CIA) is a side effect that occurs in patients with breast cancer (BC) as a result of chemotherapy. These patients require special treatments to avoid infertility and menopause. However, the factors controlling CIA, resumption of menstruation (RM), and persistence of menstruation after chemotherapy are unknown. The long-term prognosis for premenopausal patients with BC and the prognostic factors associated with CIA and RM are subject to debate. We performed a retrospective study by reviewing the medical records of 249 patients with BC (stage I to stage III) who were treated with cytotoxic chemotherapy. The median patient age was 43 (range, 26-55 years) and the median duration of follow-up was 64 months (range, 28-100 months). The medical records indicated that 219 patients (88.0%) scored as positive for the hormone receptor (HR); the majority of these patients completed chemotherapy and then received additional therapy of tamoxifen. Our analyses revealed that 88.0% (n = 219) of patients experienced CIA, and the percentage of RM during follow-up was 48.6% (n = 121). A total of 30 patients (12.0%) did not experience CIA. Disease-free survival (DFS) was affected by several factors, including tumour size ≥2 cm, node positivity, HR negative status, and body mass index ≥23 kg/m. Multivariate analysis indicated that tumour size ≥2 cm remained as a significant factor for DFS (hazard ratio = 3.3, P = 0.034). In summary, this study finds that the majority of premenopausal patients with BC (stage I to stage III) who receive chemotherapy experience CIA and subsequent RM. Although tumour size ≥2 cm is negatively associated with DFS, RM after CIA is not associated with poor prognosis.

The Nature and Extent of Help Given to Women with Intellectual Disabilities to Manage Menstruation

Science.gov (United States)

Rodgers, Jackie; Lipscombe, Jo

2005-01-01

Menstruation has been shown to be problematic for many women with intellectual disabilities. There has been a greater focus on menstrual suppression or elimination than on help and training to manage menstrual care successfully. A cross-sectional questionnaire survey was conducted in England to investigate the help and training currently given to…

Premenarcheal Mexican Girls' and Their Teachers' Perceptions of Preparation Students Receive about Menstruation at School.

Science.gov (United States)

Marvan, Luisa; Bejarano, Janett

2005-01-01

This survey explored how fifth-grade Mexican premenarcheal girls (N = 80) and their teachers (N = 16) view the preparation students receive about menstruation at school. The most discussed topics in class included hygiene and body functions. The main discrepancies between girls and teachers were as follows: (a) more teachers than girls reported…

Hypoxia and hypoxia inducible factor-1α are required for normal endometrial repair during menstruation.

Science.gov (United States)

Maybin, Jacqueline A; Murray, Alison A; Saunders, Philippa T K; Hirani, Nikhil; Carmeliet, Peter; Critchley, Hilary O D

2018-01-23

Heavy menstrual bleeding (HMB) is common and debilitating, and often requires surgery due to hormonal side effects from medical therapies. Here we show that transient, physiological hypoxia occurs in the menstrual endometrium to stabilise hypoxia inducible factor 1 (HIF-1) and drive repair of the denuded surface. We report that women with HMB have decreased endometrial HIF-1α during menstruation and prolonged menstrual bleeding. In a mouse model of simulated menses, physiological endometrial hypoxia occurs during bleeding. Maintenance of mice under hyperoxia during menses decreases HIF-1α induction and delays endometrial repair. The same effects are observed upon genetic or pharmacological reduction of endometrial HIF-1α. Conversely, artificial induction of hypoxia by pharmacological stabilisation of HIF-1α rescues the delayed endometrial repair in hypoxia-deficient mice. These data reveal a role for HIF-1 in the endometrium and suggest its pharmacological stabilisation during menses offers an effective, non-hormonal treatment for women with HMB.

Basal concentrations of oestradiol may predict the outcome of in-vitro maturation in regularly menstruating women

DEFF Research Database (Denmark)

Mikkelsen, A L; Andersson, A M; Skakkebaek, N E

2001-01-01

Retrospectively it was examined whether the number of retrieved oocytes, the maturation rate and cleavage rate can be predicted in regularly menstruating women by the use of the following predictive variables on cycle day 3-4: the concentration of FSH, oestradiol, inhibin B and inhibin A in serum...

On natural frequencies of non-uniform beams modulated by finite periodic cells

International Nuclear Information System (INIS)

Xu, Yanlong; Zhou, Xiaoling; Wang, Wei; Wang, Longqi; Peng, Fujun; Li, Bin

2016-01-01

It is well known that an infinite periodic beam can support flexural wave band gaps. However, in real applications, the number of the periodic cells is always limited. If a uniform beam is replaced by a non-uniform beam with finite periodicity, the vibration changes are vital by mysterious. This paper employs the transfer matrix method (TMM) to study the natural frequencies of the non-uniform beams with modulation by finite periodic cells. The effects of the amounts, cross section ratios, and arrangement forms of the periodic cells on the natural frequencies are explored. The relationship between the natural frequencies of the non-uniform beams with finite periodicity and the band gap boundaries of the corresponding infinite periodic beam is also investigated. Numerical results and conclusions obtained here are favorable for designing beams with good vibration control ability. - Highlights: • The transfer matrix method to study the natural frequencies of the finite periodic non-uniform beams is derived. • The transfer matrix method to study the band gaps of the infinite periodic non-uniform beams is derived. • The effects of the periodic cells on the natural frequencies are explored. • The relationships of the natural frequencies and band gap boundaries are investigated.

On natural frequencies of non-uniform beams modulated by finite periodic cells

Energy Technology Data Exchange (ETDEWEB)

Xu, Yanlong, E-mail: xuyanlong@nwpu.edu.cn [School of Aeronautics, Northwestern Polytechnical University, Xi' an 710072, Shaanxi (China); Zhou, Xiaoling [Shanghai Institute of Aerospace System Engineering, Shanghai 201109 (China); Wang, Wei [School of Aeronautics, Northwestern Polytechnical University, Xi' an 710072, Shaanxi (China); Wang, Longqi [School of Civil & Environmental Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798 (Singapore); Peng, Fujun [Shanghai Institute of Aerospace System Engineering, Shanghai 201109 (China); Li, Bin [School of Aeronautics, Northwestern Polytechnical University, Xi' an 710072, Shaanxi (China)

2016-09-23

It is well known that an infinite periodic beam can support flexural wave band gaps. However, in real applications, the number of the periodic cells is always limited. If a uniform beam is replaced by a non-uniform beam with finite periodicity, the vibration changes are vital by mysterious. This paper employs the transfer matrix method (TMM) to study the natural frequencies of the non-uniform beams with modulation by finite periodic cells. The effects of the amounts, cross section ratios, and arrangement forms of the periodic cells on the natural frequencies are explored. The relationship between the natural frequencies of the non-uniform beams with finite periodicity and the band gap boundaries of the corresponding infinite periodic beam is also investigated. Numerical results and conclusions obtained here are favorable for designing beams with good vibration control ability. - Highlights: • The transfer matrix method to study the natural frequencies of the finite periodic non-uniform beams is derived. • The transfer matrix method to study the band gaps of the infinite periodic non-uniform beams is derived. • The effects of the periodic cells on the natural frequencies are explored. • The relationships of the natural frequencies and band gap boundaries are investigated.

A technique to detect periodic and non-periodic ultra-rapid flux time variations with standard radio-astronomical data

Science.gov (United States)

Borra, Ermanno F.; Romney, Jonathan D.; Trottier, Eric

2018-06-01

We demonstrate that extremely rapid and weak periodic and non-periodic signals can easily be detected by using the autocorrelation of intensity as a function of time. We use standard radio-astronomical observations that have artificial periodic and non-periodic signals generated by the electronics of terrestrial origin. The autocorrelation detects weak signals that have small amplitudes because it averages over long integration times. Another advantage is that it allows a direct visualization of the shape of the signals, while it is difficult to see the shape with a Fourier transform. Although Fourier transforms can also detect periodic signals, a novelty of this work is that we demonstrate another major advantage of the autocorrelation, that it can detect non-periodic signals while the Fourier transform cannot. Another major novelty of our work is that we use electric fields taken in a standard format with standard instrumentation at a radio observatory and therefore no specialized instrumentation is needed. Because the electric fields are sampled every 15.625 ns, they therefore allow detection of very rapid time variations. Notwithstanding the long integration times, the autocorrelation detects very rapid intensity variations as a function of time. The autocorrelation could also detect messages from Extraterrestrial Intelligence as non-periodic signals.

A study on the menstruation of Korean adolescent girls in Seoul

Directory of Open Access Journals (Sweden)

Jin Chul Lee

2011-05-01

Full Text Available Purpose : Westernized eating habits have been associated with earlyage menstruation, which increases the incidence of dysmenorrhea and premenstrual syndrome among adolescent girls. We therefore surveyed changes in menarche timing and the general menstrual characteristics of adolescent girls in Seoul, Korea. Methods : We surveyed 538 teenage girls who visited our hospital between July and November 2007. Items explored included age at menarche, general menstrual characteristics, occurrence of premenstrual syndrome and treatment thereof, and an association between present dysmenorrhea and a family history of the condition. Results : Average age at menarche was 12.6 years, with 29% (n=156 subjects beginning menstruation at age 12 years. The prevalence of dysmenorrhea was 82% (n=435. The main symptoms were abdominal (53.2% and lower back pain (34.2%, and 15.2% of girls who experienced such symptoms required medication. Present dysmenorrhea, and a family history thereof, were statistically correlated (P&lt;0.05. In addition, 58.8% (n=316 of teenage girls had symptoms of premenstrual syndrome. The most frequent psychological symptoms were fatigue (36.4% and nervousness (38.7%, whereas the most common physical symptom was menstrual cramps (46.5%. Most subjects (87.6% tolerated the symptoms of premenstrual syndrome without medication; 11.4% took medicines including painkillers; but only 0.1% of subjects visited a doctor. Conclusion : The average age at menarche in Korean girls was 12.6 years, thus younger than in the past. Most teenage girls experienced dysmenorrhea and premenstrual syndrome, but few consulted a doctor. Organized treatment plans are required to manage menstrual problems in teenage girls.

Menarche, menopause, years of menstruation, and the incidence of osteoporosis: the influence of prenatal exposure to diethylstilbestrol.

Science.gov (United States)

Parker, Samantha E; Troisi, Rebecca; Wise, Lauren A; Palmer, Julie R; Titus-Ernstoff, Linda; Strohsnitter, William C; Hatch, Elizabeth E

2014-02-01

Estrogen is critical for bone formation and growth in women. Estrogen exposures occur throughout life, including prenatally, and change with reproductive events, such as menarche and menopause. The objective of this study was to investigate the association between age at menarche, age at menopause, and years of menstruation with incidence of osteoporosis and assess the impact of prenatal exposure to diethylstilbestrol (DES), a synthetic estrogen, on such associations. Participants were 5573 women in the National Cancer Institute Combined Cohort Study of DES (1994-2006). Data on reproductive history and medical conditions were collected through questionnaires at baseline in 1994 and subsequently in 1997, 2001, and 2006. Age-stratified Cox regression models were used to calculate multivariable incidence rate ratios (IRRs) and 95% confidence intervals (CIs). Effect measure modification by prenatal DES exposure was assessed using cubic restricted spline regression models. Osteoporosis was the main outcome measure. The IRRs for osteoporosis incidence with age at menarche less than 11 years and age at menopause of 50 years or younger were 0.82 (CI 0.59, 1.14) and 0.61 (CI 0.40, 0.92), respectively. Fewer than 25 years of menstruation was associated with an increased incidence of osteoporosis (IRR 1.80; CI 1.14, 2.86) compared with 35 years or more of menstruation. Associations were stronger among women who had not been prenatally exposed to DES. Our data support the hypothesis that lifetime cumulative exposure to estrogens is protective against osteoporosis. Furthermore, prenatal exposure to estrogen appears to modify these associations, although the mechanism by which this occurs is unknown.

Vaginal Repair of Cesarean Section Scar Diverticula that Resulted in Improved Postoperative Menstruation.

Science.gov (United States)

Zhou, Jieru; Yao, Min; Wang, Husheng; Tan, Weilin; Chen, Pin; Wang, Xipeng

2016-01-01

Owing to the increase in cesarean sections (C-sections) worldwide, long-term complications such as postmenstrual spotting, chronic pelvic pain, and C-section scar ectopic pregnancies have created a new medical era of gynecologic disease. A new type of vaginal repair is evaluated to repair C-section diverticulum (CSD) and rebuild the muscular layer to improve symptoms of abnormal uterine bleeding and decrease the risk of uterine rupture. Retrospective cohort study (Canadian Task Force classification II-2). University hospital. A total of 121 patients with CSD diagnoses by transvaginal ultrasound (TVU) presented with postmenstrual spotting between June 2012 and March 2015. All patients had undergone at least 1 C-section delivery and had no history of postmenstrual spotting before undergoing C-section. Vaginal excision and suture of CSD. The mean duration of menstruation was 14.87 ± 3.46 days preoperatively and decreased to 8.22 ± 2.73 days at 1 month after surgery, 8.89 ± 2.67 days at 3 months after surgery, and 9.02 ± 2.47 days at 6 months after surgery (p menstruation and imaging data did not differ markedly between 3 months and 6 months, suggesting that follow-up at 3 months represents an adequate endpoint for evaluating the effectiveness of surgery. At 6 months, 80.3% of patients (94 of 117) reached ≤10 days of menstruation. Further study revealed that a TRM at 6 months of ≥8.5 mm measured by TVU (relative risk [RR], 6.418; 95% confidence interval [CI], 1.478-28.443) and an interval between CS and vaginal repair of ≤2.5 years (RR, 12.0; 95% CI, 1.541- 93.454) were good prognostic factors associated with surgery. Vaginal repair of CSD improved the symptoms of postmenstrual spotting and anatomically corrected the scars. An interval between C-section and a surgery of ≤2.5 years was optimal for vaginal repair, and a TRM at 6 months of ≥8.5 mm represented the standard healing of CSD. Copyright © 2016 AAGL. Published by

Periodic orbits and non-integrability of Henon-Heiles systems

International Nuclear Information System (INIS)

Llibre, Jaume; Jimenez-Lara, Lidia

2011-01-01

We apply the averaging theory of second order to study the periodic orbits for a generalized Henon-Heiles system with two parameters, which contains the classical Henon-Heiles system. Two main results are shown. The first result provides sufficient conditions on the two parameters of these generalized systems, which guarantee that at any positive energy level, the Hamiltonian system has periodic orbits. These periodic orbits form in the whole phase space a continuous family of periodic orbits parameterized by the energy. The second result shows that for the non-integrable Henon-Heiles systems in the sense of Liouville-Arnol'd, which have the periodic orbits analytically found with averaging theory, cannot exist any second first integral of class C 1 . In particular, for any second first integral of class C 1 , we prove that the classical Henon-Heiles system and many generalizations of it are not integrable in the sense of Liouville-Arnol'd. Moreover, the tools we use for studying the periodic orbits and the non-Liouville-Arnol'd integrability can be applied to Hamiltonian systems with an arbitrary number of degrees of freedom.

'We keep it secret so no one should know'--a qualitative study to explore young schoolgirls attitudes and experiences with menstruation in rural western Kenya.

Directory of Open Access Journals (Sweden)

Linda Mason

Full Text Available BACKGROUND: Keeping girls in school offers them protection against early marriage, teen pregnancy, and sexual harms, and enhances social and economic equity. Studies report menstruation exacerbates school-drop out and poor attendance, although evidence is sparse. This study qualitatively examines the menstrual experiences of young adolescent schoolgirls. METHODS AND FINDINGS: The study was conducted in Siaya County in rural western Kenya. A sample of 120 girls aged 14-16 years took part in 11 focus group discussions, which were analysed thematically. The data gathered were supplemented by information from six FGDs with parents and community members. Emergent themes were: lack of preparation for menarche; maturation and sexual vulnerability; menstruation as an illness; secrecy, fear and shame of leaking; coping with inadequate alternatives; paying for pads with sex; and problems with menstrual hygiene. Girls were unprepared and demonstrated poor reproductive knowledge, but devised practical methods to cope with menstrual difficulties, often alone. Parental and school support of menstrual needs is limited, and information sparse or inaccurate. Girls' physical changes prompt boys and adults to target and brand girls as ripe for sexual activity including coercion and marriage. Girls admitted 'others' rather than themselves were absent from school during menstruation, due to physical symptoms or inadequate sanitary protection. They described difficulties engaging in class, due to fear of smelling and leakage, and subsequent teasing. Sanitary pads were valued but resource and time constraints result in prolonged use causing chafing. Improvised alternatives, including rags and grass, were prone to leak, caused soreness, and were perceived as harmful. Girls reported 'other girls' but not themselves participated in transactional sex to buy pads, and received pads from boyfriends. CONCLUSIONS: In the absence of parental and school support, girls cope

Global asymptotical ω-periodicity of a fractional-order non-autonomous neural networks.

Science.gov (United States)

Chen, Boshan; Chen, Jiejie

2015-08-01

We study the global asymptotic ω-periodicity for a fractional-order non-autonomous neural networks. Firstly, based on the Caputo fractional-order derivative it is shown that ω-periodic or autonomous fractional-order neural networks cannot generate exactly ω-periodic signals. Next, by using the contraction mapping principle we discuss the existence and uniqueness of S-asymptotically ω-periodic solution for a class of fractional-order non-autonomous neural networks. Then by using a fractional-order differential and integral inequality technique, we study global Mittag-Leffler stability and global asymptotical periodicity of the fractional-order non-autonomous neural networks, which shows that all paths of the networks, starting from arbitrary points and responding to persistent, nonconstant ω-periodic external inputs, asymptotically converge to the same nonconstant ω-periodic function that may be not a solution. Copyright © 2015 Elsevier Ltd. All rights reserved.

Managing menstruation in the workplace: an overlooked issue in low- and middle-income countries.

OpenAIRE

Sommer, Marni; Chandraratna, Sahani; Cavill, Sue; Mahon, Therese; Phillips-Howard, Penelope

2016-01-01

The potential menstrual hygiene management barriers faced by adolescent girls and women in workplace environments in low- and middle-income countries has been under addressed in research, programming and policy. Despite global efforts to reduce poverty among women in such contexts, there has been insufficient attention to the water and sanitation related barriers, specifically in relation to managing monthly menstruation, that may hinder girls? and women?s contributions to the workplace, and ...

The effect of menstruation on chosen physiological and biochemical reactions caused by the physical effort with the submaximal intensity

Directory of Open Access Journals (Sweden)

P Zieliński

2003-03-01

Full Text Available The aim of this work was to determine the influence of the menstruation phase on changes of respective indicators of the gas exchange and on biochemical parameters of blood during physical efforts with the sub-maximal intensity. Fifteen female students of the Academy of Physical Education took part in the study. Girls were aged from 19 to 22 years old and did not practice sports. The effort tests were conducted in the follicular and luteal phase of two succeeding menstrual cycles. As far the aerobic capacity determination is concerned, one cyclo-ergometric test with graded effort was conducted and it was performed till the “refusal”. It allowed to mark a threshold (TDMA and a maximal level of physiological and biochemical indicators. Basing on the results of the graded test individual loads were determined for every next effort trial (repeated 4 times in every phase of the two succeeding menstrual cycles. The aim of this trial was to evaluate the reaction of women’s constitution on work with the sub-maximal intensity. The above trial consisted on two 10 min efforts divided with the 2 min pause (the first effort with the intensity of 80% of the TDMA threshold, second with the intensity bigger about 30-40% of difference between TDMA and a maximal load established by the graded test. The research did not reveal statistically significant differentiation as considering effort changes of basic physiological and biochemical indicators, determining reaction of women’s organisms on work with the sub- and over- threshold intensity (TDMA. It showed that menstruation has not significant effect on the level of changes of analysed parameters caused by the physical effort with the sub-maximal intensity.

The impact of menstruation in adolescents with disabilities related to cerebral palsy.

Science.gov (United States)

Zacharin, Margaret; Savasi, Ingrid; Grover, Sonia

2010-07-01

Information regarding menstrual difficulties for adolescents with developmental disabilities and their families is limited. To assess the impact of menstruation on adolescents with developmental disabilities and their families, and to compare this to previously reported experiences of age-matched normal girls. Families of girls aged 12-18 years with known disabilities, attending the Royal Children's Hospital, Melbourne, were recruited into a questionnaire based study evaluating issues of menstruation and associated problems, together with the consequent psychological, social and emotional impact on their families and carers. Information was sought regarding menstrual management strategies, outcome satisfaction and specific areas of family concern. 103 questionnaires were completed. The average age of participating girls was 15.11 years, mean menarchal age 12.3 years. 79 girls were postmenarchal. The severity of menstrual problems was similar to a normal population. 59 (76%) were happy with the impact of menses on their social activities. More than 50% sought menstrual advice before menarche. Advice seeking strongly correlated with disability severity (p=0.01) and impact of menses on social activities (p=0.01), which in turn were highly predictive of seeking assistance (p=0.005). Carer satisfaction with current management inversely correlated with treatment seeking behaviour (p=0.034). Menstrual characteristics in this population are similar to those without disabilities. There is a high level of parental anxiety regarding the impact of menses, particularly when disability is severe. Medical therapies may be required but information for families is lacking. Clinicians should play a proactive and educational role with families and adolescents with disabilities.

Knowledge, Practices, and Restrictions Related to Menstruation among Young Women from Low Socioeconomic Community in Mumbai, India

Science.gov (United States)

Thakur, Harshad; Aronsson, Annette; Bansode, Seema; Stalsby Lundborg, Cecilia; Dalvie, Suchitra; Faxelid, Elisabeth

2014-01-01

The main objective was to assess knowledge, practices, and restrictions faced by young women regarding their menstrual hygiene. The views of adult women having young daughters were also included and both views were compared. In addition, the factors influencing the menstrual hygiene practices were also studied. The study was carried out during 2008 in Mumbai, India. The mixed methods approach was followed for the data collection. Both qualitative and quantitative methods were used to collect the data. For quantitative survey, totally 192 respondents (96 adult and 96 younger women) were selected. While young women were asked about questions related to their menstruation, adult women were asked questions to find out how much they know about menstrual history of their daughters. The qualitative data helped to supplement the findings from the quantitative survey and to study the factors affecting menstrual practices in young women. The mean age at menarche reported was 13.4 years and 30–40% of young girls did not receive any information about menstruation before menarche. It is thus seen that very few young girls between the age group 15 and 24 years did receive any information before the onset of menstruation. Among those who received some information, it was not adequate enough. The source of information was also not authentic. Both young and adult women agreed on this. Due to the inadequate knowledge, there were certain unhygienic practices followed by the young girls resulting in poor menstrual hygiene. It also leads to many unnecessary restrictions on young girls and they faced many health problems and complaints, which were either ignored or managed inappropriately. The role of health sector was almost negligible from giving information to the management of health problems of these young girls. This paper reemphasizes the important, urgent, and neglected need of providing correct knowledge to the community including adolescent girls. PMID:25072044

Knowledge, Practices, and Restrictions Related to Menstruation among Young Women from Low Socioeconomic Community in Mumbai, India.

Science.gov (United States)

Thakur, Harshad; Aronsson, Annette; Bansode, Seema; Stalsby Lundborg, Cecilia; Dalvie, Suchitra; Faxelid, Elisabeth

2014-01-01

The main objective was to assess knowledge, practices, and restrictions faced by young women regarding their menstrual hygiene. The views of adult women having young daughters were also included and both views were compared. In addition, the factors influencing the menstrual hygiene practices were also studied. The study was carried out during 2008 in Mumbai, India. The mixed methods approach was followed for the data collection. Both qualitative and quantitative methods were used to collect the data. For quantitative survey, totally 192 respondents (96 adult and 96 younger women) were selected. While young women were asked about questions related to their menstruation, adult women were asked questions to find out how much they know about menstrual history of their daughters. The qualitative data helped to supplement the findings from the quantitative survey and to study the factors affecting menstrual practices in young women. The mean age at menarche reported was 13.4 years and 30-40% of young girls did not receive any information about menstruation before menarche. It is thus seen that very few young girls between the age group 15 and 24 years did receive any information before the onset of menstruation. Among those who received some information, it was not adequate enough. The source of information was also not authentic. Both young and adult women agreed on this. Due to the inadequate knowledge, there were certain unhygienic practices followed by the young girls resulting in poor menstrual hygiene. It also leads to many unnecessary restrictions on young girls and they faced many health problems and complaints, which were either ignored or managed inappropriately. The role of health sector was almost negligible from giving information to the management of health problems of these young girls. This paper reemphasizes the important, urgent, and neglected need of providing correct knowledge to the community including adolescent girls.

Calculational framework for safety analyses of non-reactor nuclear facilities

International Nuclear Information System (INIS)

Coleman, J.R.

1994-01-01

A calculational framework for the consequences analysis of non-reactor nuclear facilities is presented. The analysis framework starts with accident scenarios which are developed through a traditional hazard analysis and continues with a probabilistic framework for the consequences analysis. The framework encourages the use of response continua derived from engineering judgment and traditional deterministic engineering analyses. The general approach consists of dividing the overall problem into a series of interrelated analysis cells and then devising Markov chain like probability transition matrices for each of the cells. An advantage of this division of the problem is that intermediate output (as probability state vectors) are generated at each calculational interface. The series of analyses when combined yield risk analysis output. The analysis approach is illustrated through application to two non-reactor nuclear analyses: the Ulysses Space Mission, and a hydrogen burn in the Hanford waste storage tanks

The Association between Endometriomas and Ovarian Cancer: Preventive Effect of Inhibiting Ovulation and Menstruation during Reproductive Life.

Science.gov (United States)

Grandi, Giovanni; Toss, Angela; Cortesi, Laura; Botticelli, Laura; Volpe, Annibale; Cagnacci, Angelo

2015-01-01

Although endometriosis frequently involves multiple sites in the pelvis, malignancies associated with this disease are mostly confined to the ovaries, evolving from an endometrioma. Endometriomas present a 2-3-fold increased risk of transformation in clear-cell, endometrioid, and possibly low-grade serous ovarian cancers, but not in mucinous ovarian cancers. These last cancers are, in some aspects, different from the other epithelial ovarian cancers, as they do not appear to be decreased by the inhibition of ovulation and menstruation. The step by step process of transformation from typical endometrioma, through atypical endometrioma, finally to ovarian cancer seems mainly related to oxidative stress, inflammation, hyperestrogenism, and specific molecular alterations. Particularly, activation of oncogenic KRAS and PI3K pathways and inactivation of tumor suppressor genes PTEN and ARID1A are suggested as major pathogenic mechanisms for endometriosis associated clear-cell and endometrioid ovarian cancer. Both the risk for endometriomas and their associated ovarian cancers seems to be highly and similarly decreased by the inhibition of ovulation and retrograde menstruation, suggesting a common pathogenetic mechanism and common possible preventive strategies during reproductive life.

High exposure to progesterone between the end of menstruation and the day of triggering final oocyte maturation is associated with a decreased probability of pregnancy in patients treated by in vitro fertilization and intracytoplasmic sperm injection.

Science.gov (United States)

Kyrou, Dimitra; Kolibianakis, Efstratios M; Fatemi, Human M; Camus, Michel; Tournaye, Herman; Tarlatzis, Basil C; Devroey, Paul

2011-10-01

To investigate the association between the probability of pregnancy and hormone exposure between the end of menstruation and the day of triggering final oocyte maturation (menstruation-free interval). Prospective study. University. One hundred women (aged ≤ 39 years) stimulated with a fixed dose of recombinant follicle-stimulating hormone (200 IU). Daily gonadotropin-releasing hormone antagonist (GnRH, 0.25 mg) used from day 6 of stimulation onward, final oocyte maturation triggered by administration of 10,000 IU of human chorionic gonadotropin (hCG) as soon as ≥ 3 follicles ≥ 17 mm were present, and hormone assessment performed at initiation of stimulation, on the first day after menstruation had stopped, on the day of antagonist initiation, and on the day of hCG administration. The association between hormone exposure during the menstruation-free interval and the probability of ongoing pregnancy. The exposure to progesterone during the menstruation-free interval was statistically significantly higher in patients who did not become pregnant compared with those who did (4.20 ± 2.54 vs. 3.13 ± 1.14, respectively). Binary logistic regression confirmed the adverse effect of the increased exposure to progesterone for the achievement of pregnancy. In recombinant follicle-stimulating hormone/gonadotropin-releasing hormone antagonist in vitro fertilization/intracytoplasmic sperm injection cycles, a lower probability of pregnancy is associated with a higher exposure to progesterone during the menstruation-free interval. Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

Real space method of powder diffraction for non-periodic and nearly periodic materials

International Nuclear Information System (INIS)

Egami, T.; Toby, B.H.; Dmowski, W.; Janot, C.; Jorgensen, J.D.

1990-01-01

The use of high-energy neutrons from pulsed or hot sources allows the method of atomic pair distribution analysis to be applied to the structural determination of crystalline as well as amorphous solids. This method complements the standard crystallographic methods in studying non-periodic aspects of solids with or without long range order

‘We Keep It Secret So No One Should Know’ – A Qualitative Study to Explore Young Schoolgirls Attitudes and Experiences with Menstruation in Rural Western Kenya

Science.gov (United States)

Mason, Linda; Nyothach, Elizabeth; Alexander, Kelly; Odhiambo, Frank O.; Eleveld, Alie; Vulule, John; Rheingans, Richard; Laserson, Kayla F.; Mohammed, Aisha; Phillips-Howard, Penelope A.

2013-01-01

Background Keeping girls in school offers them protection against early marriage, teen pregnancy, and sexual harms, and enhances social and economic equity. Studies report menstruation exacerbates school-drop out and poor attendance, although evidence is sparse. This study qualitatively examines the menstrual experiences of young adolescent schoolgirls. Methods and Findings The study was conducted in Siaya County in rural western Kenya. A sample of 120 girls aged 14–16 years took part in 11 focus group discussions, which were analysed thematically. The data gathered were supplemented by information from six FGDs with parents and community members. Emergent themes were: lack of preparation for menarche; maturation and sexual vulnerability; menstruation as an illness; secrecy, fear and shame of leaking; coping with inadequate alternatives; paying for pads with sex; and problems with menstrual hygiene. Girls were unprepared and demonstrated poor reproductive knowledge, but devised practical methods to cope with menstrual difficulties, often alone. Parental and school support of menstrual needs is limited, and information sparse or inaccurate. Girls’ physical changes prompt boys and adults to target and brand girls as ripe for sexual activity including coercion and marriage. Girls admitted ‘others’ rather than themselves were absent from school during menstruation, due to physical symptoms or inadequate sanitary protection. They described difficulties engaging in class, due to fear of smelling and leakage, and subsequent teasing. Sanitary pads were valued but resource and time constraints result in prolonged use causing chafing. Improvised alternatives, including rags and grass, were prone to leak, caused soreness, and were perceived as harmful. Girls reported ‘other girls’ but not themselves participated in transactional sex to buy pads, and received pads from boyfriends. Conclusions In the absence of parental and school support, girls cope, sometimes

Reframing menstruation in India: metamorphosis of the menstrual taboo with the changing media coverage.

Science.gov (United States)

Yagnik, Arpan Shailesh

2014-01-01

In this study I hypothesize metamorphosis of the menstrual taboo by examining the image and perception shifts of two social taboos-HIV/AIDS and homosexuality-from estranged taboos to embraced social issues. Trends identified in their media framing and respective image shifts were applied to menstruation in India. Based on my understanding of theory, topic, and geographical location, I construct a metamorphosis. I contribute the hypothesized final stage of metamorphosis, and explain how framing is likely instrumental in bringing about these changes.

Non-reciprocal wave propagation in one-dimensional nonlinear periodic structures

Directory of Open Access Journals (Sweden)

Benbiao Luo

2018-01-01

Full Text Available We study a one-dimensional nonlinear periodic structure which contains two different spring stiffness and an identical mass in each period. The linear dispersion relationship we obtain indicates that our periodic structure has obvious advantages compared to other kinds of periodic structures (i.e. those with the same spring stiffness but two different mass, including its increased flexibility for manipulating the band gap. Theoretically, the optical cutoff frequency remains unchanged while the acoustic cutoff frequency shifts to a lower or higher frequency. A numerical simulation verifies the dispersion relationship and the effect of the amplitude-dependent signal filter. Based upon this, we design a device which contains both a linear periodic structure and a nonlinear periodic structure. When incident waves with the same, large amplitude pass through it from opposite directions, the output amplitude of the forward input is one order magnitude larger than that of the reverse input. Our devised, non-reciprocal device can potentially act as an acoustic diode (AD without an electrical circuit and frequency shifting. Our result represents a significant step forwards in the research of non-reciprocal wave manipulation.

Estimating the period of a cyclic non-homogeneous Poisson process

NARCIS (Netherlands)

Belitser, E.; Andrade Serra, De P.J.; Zanten, van J.H.

2013-01-01

Motivated by applications of Poisson processes for modelling periodic time-varying phenomena, we study a semi-parametric estimator of the period of cyclic intensity function of a non-homogeneous Poisson process. There are no parametric assumptions on the intensity function which is treated as an

Real-time method of powder diffraction for non-periodic and nearly periodic materials

International Nuclear Information System (INIS)

Egami, T.; Toby, B.H.; Dmowski, T.W.; Jorgensen, J.D.

1989-12-01

The use of high-energy neutrons from pulsed or hot sources allows the method of atomic pair distribution analysis to be applied to the structural determination of crystalline as well as amorphous solids. This method complements the standard crystallographic methods in studying non-periodic aspects of solids with or without long range order. 14 refs., 3 figs

Non-thyroid cancer in Northern Ukraine in the post-Chernobyl period: Short report.

Science.gov (United States)

Hatch, M; Ostroumova, E; Brenner, A; Federenko, Z; Gorokh, Y; Zvinchuk, O; Shpak, V; Tereschenko, V; Tronko, M; Mabuchi, K

2015-06-01

The Chernobyl nuclear power plant accident in Ukraine in 1986 led to widespread radioactive releases into the environment - primarily of radioiodines and cesium - heavily affecting the northern portions of the country, with settlement-averaged thyroid doses estimated to range from 10 mGy to more than 10 Gy. The increased risk of thyroid cancer among exposed children and adolescents is well established but the impact of radioactive contamination on the risk of other types of cancer is much less certain. To provide data on a public health issue of major importance, we have analyzed the incidence of non-thyroid cancers during the post-Chernobyl period in a well-defined cohort of 13,203 individuals who were <18 years of age at the time of the accident. The report is based on standardized incidence ratio (SIR) analysis of 43 non-thyroid cancers identified through linkage with the National Cancer Registry of Ukraine for the period 1998 through 2009. We compared the observed and expected number of cases in three cancer groupings: all solid cancers excluding thyroid, leukemia, and lymphoma. Our analyses found no evidence of a statistically significant elevation in cancer risks in this cohort exposed at radiosensitive ages, although the cancer trends, particularly for leukemia (SIR=1.92, 95% confidence interval: 0.69; 4.13), should continue to be monitored. Copyright © 2015 Elsevier Ltd. All rights reserved.

Military women's attitudes toward menstruation and menstrual suppression in relation to the deployed environment: development and testing of the MWATMS-9 (short form).

Science.gov (United States)

Trego, Lori L; Jordan, Patricia J

2010-01-01

To determine military women's attitudes toward menstruation and menstrual suppression with oral contraceptives in the deployed environment. A cross-sectional descriptive design with the administration of the Menstrual Attitude Questionnaire (MAQ) and the 55-item Military Women's Attitudes Towards Menstrual Suppression Scale (MWATMS) to a convenience sample (n = 278) of women in the U.S. Army with deployment experience. The MAQ's five subscales' mean scores ranged from 3.4 (+/-1.11) to 5.1 (+/-1.06), indicating neutral to moderate attitudes toward menstruation. Measurement development on the MWATMS produced a nine-item scale with three components: stress effects, benefits to self, and environmental barriers. Menstrual attitudes were generally neutral in this sample; however, military women favor menstrual suppression during deployment owing to the effects of stress during deployment, benefits that suppression would provide, and the barriers to menstrual hygiene in the deployed environment. Women who perceived menstruation as bothersome and debilitating had positive attitudes toward menstrual suppression. These findings can contribute to appropriate predeployment women's health care and improve the readiness for deployment in female soldiers. Providers should educate women on the risks and benefits of menstrual suppression methods and provide guidance on impact that the deployed environment can have on their menstrual experiences.

Predictors of female worker attitudes towards menstruation and the provision of help to institutionalized women with intellectual disabilities in Taiwan.

Science.gov (United States)

Chou, Yueh-Ching; Lu, Zxy-yann J; Pu, Cheng-yun; Lan, Chung-Fu

2008-08-01

No previous research has examined the importance of both individual and environmental factors for predicting caregivers' menstrual attitudes. To explore the predictors of female caregivers' attitudes towards menstruation and the help they give to women with intellectual disabilities, we conducted a cross-sectional questionnaire survey which was completed by 725 female workers from 12 institutions in Taiwan. The Menstrual Attitudes Questionnaire (MAQ) and a structured questionnaire were used. Logistic regression analysis revealed that individual characteristics such as age and education were significantly associated with menstrual attitudes of female caregivers working with institutionalized women with intellectual disabilities. Furthermore, the environmental context, such as the frequency of discussions with colleagues, training in menstrual management care and the level of difficulty when giving help in menstruation management, was important for improving caregivers' menstrual attitudes. This study contributes to the existing literature by determining both individual and environmental predictors of caregivers' menstrual attitudes.

Understanding and defining sanitation insecurity: women’s gendered experiences of urination, defecation and menstruation in rural Odisha, India

Science.gov (United States)

Clasen, Thomas F; Hadley, Craig; Yount, Kathryn M; Haardörfer, Regine; Rout, Manaswini; Dasmohapatra, Munmun; Cooper, Hannah LF

2017-01-01

Background Research suggests that the lived experience of inadequate sanitation may contribute to poor health outcomes above and beyond pathogen exposure, particularly among women. The goal of this research was to understand women’s lived experiences of sanitation by documenting their urination-related, defecation-related and menstruation-related concerns, to use findings to develop a definition of sanitation insecurity among women in low-income settings and to develop a conceptual model to explain the factors that contribute to their experiences, including potential behavioural and health consequences. Methods We conducted 69 Free-List Interviews and eight focus group discussions in a rural population in Odisha, India to identify women’s sanitation concerns and to build an understanding of sanitation insecurity. Findings We found that women at different life stages in rural Odisha, India have a multitude of unaddressed urination, defecation and menstruation concerns. Concerns fell into four domains: the sociocultural context, the physical environment, the social environment and personal constraints. These varied by season, time of day, life stage and toilet ownership, and were linked with an array of adaptations (ie, suppression, withholding food and water) and consequences (ie, scolding, shame, fear). Our derived definition and conceptual model of sanitation insecurity reflect these four domains. Discussion To sincerely address women’s sanitation needs, our findings indicate that more is needed than facilities that change the physical environment alone. Efforts to enable urinating, defecating and managing menstruation independently, comfortably, safely, hygienically, privately, healthily, with dignity and as needed require transformative approaches that also address the gendered, sociocultural and social environments that impact women despite facility access. This research lays the groundwork for future sanitation studies to validate or refine the proposed

'Gushing Out Blood': Defloration and Menstruation in Memoirs of a Woman of Pleasure.

Science.gov (United States)

Read, Sara

2018-06-01

John Cleland's 1740s pornographic novel, Memoirs of a Woman of Pleasure repeatedly depicts and eroticises the act of defloration. As such it is a revealing illustration of what Ivan Bloch termed the 'defloration mania' of the eighteenth century. This article maps narrative events on to contemporary medical depictions of first intercourse to show the ways that the theories and ideas presented in medical and pseudo-medical texts transferred into erotic fiction and demonstrates how in some instances the bloody defloration scenes can be read as being sex during menstruation, an act which was culturally forbidden at this time.

Comment: Distinguishing Cohort Effects from Age*Period Effects on Non-Marital Fertility

Science.gov (United States)

Martin, Steve

2009-01-01

In the article "Cohort Effects on Non-marital Fertility," in this issue of "Social Forces," Jean Stockard employs a novel strategy for disentangling cohort, period, and age effects on the non-marital fertility ratio. In a model with fixed-effect controls for age and for time period, the author documents evidence for three cohort-specific factors…

Non-resonant terahertz field enhancement in periodically arranged nanoslits

DEFF Research Database (Denmark)

Novitsky, Andrey; Ivinskaya, Aliaksandra; Zalkovskij, Maksim

2012-01-01

We analyze ultra strong non-resonant field enhancement of THz field in periodic arrays of nanoslits cut in ultrathin metal films. The main feature of our approach is that the slit size and metal film thickness are several orders of magnitude smaller than the wavelength λ of the impinging radiatio...... by the microscopic Drude-Lorentz model taking into account retardation processes in the metal film and validated by the finite difference frequency domain method. We expect sensor and modulation applications of the predicted giant broadband field enhancement.......We analyze ultra strong non-resonant field enhancement of THz field in periodic arrays of nanoslits cut in ultrathin metal films. The main feature of our approach is that the slit size and metal film thickness are several orders of magnitude smaller than the wavelength λ of the impinging radiation...... approaches the THz wavelength but before entering the Raleigh-Wood anomaly, the field enhancement in nanoslit stays close to that in a single isolated slit, i.e., the well-known inversefrequency dependence. Both regimes are non-resonant and thus extremely broadband for P

Non-periodic molecular dynamics simulations of coarse grained lipid bilayer in water

DEFF Research Database (Denmark)

Kotsalis, E. M.; Hanasaki, I.; Walther, Jens Honore

2010-01-01

We present a multiscale algorithm that couples coarse grained molecular dynamics (CGMD) with continuum solver. The coupling requires the imposition of non-periodic boundary conditions on the coarse grained Molecular Dynamics which, when not properly enforced, may result in spurious fluctuations o...... in simulating more complex systems by performing a non-periodic Molecular Dynamics simulation of a DPPC lipid in liquid coarse grained water.......We present a multiscale algorithm that couples coarse grained molecular dynamics (CGMD) with continuum solver. The coupling requires the imposition of non-periodic boundary conditions on the coarse grained Molecular Dynamics which, when not properly enforced, may result in spurious fluctuations...... of the material properties of the system represented by CGMD. In this paper we extend a control algorithm originally developed for atomistic simulations [3], to conduct simulations involving coarse grained water molecules without periodic boundary conditions. We demonstrate the applicability of our method...

The Ratio Evolution Analysis of the Non-Performing Loans Obtained by the Credit Institutions in Romania during the Period 2007-2015

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Mirela Catalina Turkes

2015-06-01

Full Text Available This article analyses the ratio evolution of the non-performing loans obtained by the privately, Romanian and foreign-owned credit institutions, in Romania, during the period December 2007 - June 2015, depending on the change of the legislation regarding the reporting methodology for the purpose of the institutions surveillance according to the prudential regulations of BNR (National Bank of Romania and EU Regulation. The results of this analysis highlighted the fact that the non-performing loans ratio went through a spectacular increase during the period 2007-2013, reaching 21.87% following the promotion of a strategic plan based on the recovery of the debts by restructuring actions, rescheduling or enforcement. In 2014, the non-performing loans ratio decreases to 15.33% following the modification of the debt recovery strategic plan by taking them out from the balance sheet and by their integral provisioning.

Impact of menstruation on select hematology and clinical chemistry variables in cynomolgus macaques.

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Perigard, Christopher J; Parrula, M Cecilia M; Larkin, Matthew H; Gleason, Carol R

2016-06-01

In preclinical studies with cynomolgus macaques, it is common to have one or more females presenting with menses. Published literature indicates that the blood lost during menses causes decreases in red blood cell mass variables (RBC, HGB, and HCT), which would be a confounding factor in the interpretation of drug-related effects on clinical pathology data, but no scientific data have been published to support this claim. This investigation was conducted to determine if the amount of blood lost during menses in cynomolgus macaques has an effect on routine hematology and serum chemistry variables. Ten female cynomolgus macaques (Macaca fascicularis), 5 to 6.5 years old, were observed daily during approximately 3 months (97 days) for the presence of menses. Hematology and serum chemistry variables were evaluated twice weekly. The results indicated that menstruation affects the erythrogram including RBC, HGB, HCT, MCHC, MCV, reticulocyte count, RDW, the leukogram including neutrophil, lymphocyte, and monocyte counts, and chemistry variables, including GGT activity, and the concentrations of total proteins, albumin, globulins, and calcium. The magnitude of the effect of menstruation on susceptible variables is dependent on the duration of the menstrual phase. Macaques with menstrual phases lasting ≥ 7 days are more likely to develop changes in variables related to chronic blood loss. In preclinical toxicology studies with cynomolgus macaques, interpretation of changes in several commonly evaluated hematology and serum chemistry variables requires adequate clinical observation and documentation concerning presence and duration of menses. There is a concern that macaques with long menstrual cycles can develop iron deficiency anemia due to chronic menstrual blood loss. © 2016 American Society for Veterinary Clinical Pathology.

Non-periodic one-dimensional ideal conductors and integrable turbulence

Energy Technology Data Exchange (ETDEWEB)

Zakharov, Dmitry V. [Courant Institute of Mathematical Sciences, New York University, 251 Mercer Street, New York, NY, 10012 (United States); Zakharov, Vladimir E. [Department of Mathematics, University of Arizona, Tucson, AZ, 85791 (United States); Dyachenko, Sergey A., E-mail: sdyachen@math.uiuc.edu [Department of Mathematics, University of Illinois, Urbana-Champaign, IL, 61801 (United States)

2016-12-01

Highlights: • An efficient procedure for construction of non-periodic, non-vanishing reflectionless potentials is presented. • The analytical procedure is reinforced by numerical simulation that presents some of these potentials. • The present work is a key ingredient for the study of integrable turbulence and statistical description of “solitonic gas”. - Abstract: To relate the motion of a quantum particle to the properties of the potential is a fundamental problem of physics, which is far from being solved. Can a medium with a potential which is neither periodic nor quasi-periodic be a conductor? That question seems to have been never addressed, despite being both interesting and having practical importance. Here we propose a new approach to the spectral problem of the one-dimensional Schrödinger operator with a bounded potential. We construct a wide class of potentials having a spectrum consisting of the positive semiaxis and finitely many bands on the negative semiaxis. These potentials, which we call primitive, are reflectionless for positive energy and in general are neither periodic nor quasi-periodic. Moreover, they can be stochastic, and yet allow ballistic transport, and thus describe one-dimensional ideal conductors. Primitive potentials also generate a new class of solutions of the KdV hierarchy. Stochastic primitive potentials describe integrable turbulence, which is important for hydrodynamics and nonlinear optics. We construct the potentials by numerically solving a system of singular integral equations. We hypothesize that finite-gap potentials are a subclass of primitive potentials, and prove this in the case of one-gap potentials.

ACOG Committee Opinion No. 651: Menstruation in Girls and Adolescents: Using the Menstrual Cycle as a Vital Sign.

Science.gov (United States)

2015-12-01

Despite variations worldwide and within the U.S. population, median age at menarche has remained relatively stable-between 12 years and 13 years-across well-nourished populations in developed countries. Environmental factors, including socioeconomic conditions, nutrition, and access to preventive health care, may influence the timing and progression of puberty. A number of medical conditions can cause abnormal uterine bleeding, characterized by unpredictable timing and variable amount of flow. Clinicians should educate girls and their caretakers (eg, parents or guardians) about what to expect of a first menstrual period and the range for normal cycle length of subsequent menses. Identification of abnormal menstrual patterns in adolescence may improve early identification of potential health concerns for adulthood. It is important for clinicians to have an understanding of the menstrual patterns of adolescent girls, the ability to differentiate between normal and abnormal menstruation, and the skill to know how to evaluate the adolescent girl patient. By including an evaluation of the menstrual cycle as an additional vital sign, clinicians reinforce its importance in assessing overall health status for patients and caretakers.

Therapeutic and Ethical Dilemma of Puberty and Menstruation Problems in an Intellectually Disabled (Autistic) Female: a Case Report.

Science.gov (United States)

Memarian, Azadeh; Mehrpisheh, Shahrokh

2015-10-01

Intellectual disability is a term used when a person has certain limitations in mental functioning and skills. Autism is a group of developmental brain disorders, collectively called autism spectrum disorder (ASD). Teenagers with learning and physical disabilities are more likely to have menstrual problems compared to the general populations. The parents of a 12-year-old girl with autism spectrum disorder and intellectual disability referred to the coroner due to her numerous problems of puberty (menstruation) including: poor hygiene and polluting herself and the environment, not allowing to put or change the pads and changes in mood and physical health prior period, requested for the surgery (hysterectomy). In legal medicine organization after reviewing the medical records, physical exams and medical consultations with a gynecologist and psychiatric, surgery was not accepted. Hysterectomy (surgery) due to the age of the child, either physically or morally is not recommended. The use of hormone replacement therapy has side effects such as osteoporosis. In these cases, it seems noninvasive methods (behavioral therapy and learning care skills) under the welfare experts is also more effective and morally.

Special Features In Turbulent Mixing. Comparison between Periodic and Non Periodic Case

Directory of Open Access Journals (Sweden)

Mihai Costescu

2006-12-01

Full Text Available After hundreds of years of stability study, the problems of flow kinematics are far from complete solving. A modern theory appears in this field: the mixing theory. Its mathematical methods and techniques developed the significant relation between turbulence and chaos. The turbulence is an important feature of dynamic systems with few freedom degrees, the so-called far from equilibrium systems. These are widespread between the models of excitable media.Studying a mixing for a flow implies the analysis of successive stretching and folding phenomena for its particles, the influence of parameters and initial conditions. In the previous works, the study of the 3D non-periodic models exhibited a quite complicated behavior, involving some significant events - the so-called rare events. The variation of parameters had a great influence on the length and surface deformations. The 2D (periodic case is simpler, but significant events can also issue for irrational values of the length and surface versors, as was the situation in 3D case.The comparison between 2D and 3D case revealed interesting properties; therefore a modified 2D (periodic model is tested. The numerical simulations were realized in MapleVI, for searching special mathematical events. Continuing this work both from analytical and numeric standpoint would relieve useful properties for the turbulent mixing. A proximal target is to test some special functions for the periodic model, and to study the behavior of the structures realized by the model.

Subclinical impairment of ovarian reserve in systemic lupus erythematosus patients with normal menstruation not using alkylating therapy.

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Ma, Wenhong; Zhan, Zhongping; Liang, Xiaoyan; Chen, Jianhui; Huang, Xingfang; Liao, Caiyun

2013-12-01

Disease activity is a major factor in menstrual disorders in systemic lupus erythematosus (SLE) patients not receiving alkylating therapy. However, the ovarian reserve of SLE women with normal menstruation is still unclear. Twenty-three SLE patients naïve to cytotoxic agents (SLE group) and nineteen SLE patients receiving current or previous cyclophosphamide (CTX) therapy (without other cytotoxic agents; SLE-CTX group) were enrolled. Twenty-one age-matched healthy women served as controls. All patients and controls had a regular menstrual cycle. Basal hormone levels, including follicle-stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), and anti-Müllerian hormone (AMH), and antral follicle count (AFC) were analyzed in the two study groups and compared with the control group. No significant differences were found between the SLE, SLE-CTX, and control groups in age, body mass index (BMI), and basal FSH and LH levels. The E2 (P=0.023) levels were high and the AMH (P=0.000) values and AFC (P=0.001) were significantly lower in the SLE and SLE-CTX groups compared to control. However, these values were similar between the SLE and SLE-CTX groups. SLE patients not receiving alkylating therapy who had normal menstruation and short illness duration still had an impaired ovarian reserve.

Suppressing non-periodically repeating disturbances in mechanical servo systems

NARCIS (Netherlands)

Tousain, R.L.; Boissy, J.C.; Norg, M.L.; Steinbuch, M.; Bosgra, O.H.

1998-01-01

Non-periodically repeating (NPR) disturbances are fixed-shape disturbances that occur randomly in time. We can provide a control system with the capability to suppress this type of disturbance by adding in parallel to the input of the nominal feedback controller a learning look-up-table based

Temporal and Periodic Variations of Sunspot Counts in Flaring and Non-Flaring Active Regions

Science.gov (United States)

Kilcik, A.; Yurchyshyn, V.; Donmez, B.; Obridko, V. N.; Ozguc, A.; Rozelot, J. P.

2018-04-01

We analyzed temporal and periodic variations of sunspot counts (SSCs) in flaring (C-, M-, or X-class flares), and non-flaring active regions (ARs) for nearly three solar cycles (1986 through 2016). Our main findings are as follows: i) temporal variations of monthly means of the daily total SSCs in flaring and non-flaring ARs behave differently during a solar cycle and the behavior varies from one cycle to another; during Solar Cycle 23 temporal SSC profiles of non-flaring ARs are wider than those of flaring ARs, while they are almost the same during Solar Cycle 22 and the current Cycle 24. The SSC profiles show a multi-peak structure and the second peak of flaring ARs dominates the current Cycle 24, while the difference between peaks is less pronounced during Solar Cycles 22 and 23. The first and second SSC peaks of non-flaring ARs have comparable magnitude in the current solar cycle, while the first peak is nearly absent in the case of the flaring ARs of the same cycle. ii) Periodic variations observed in the SSCs profiles of flaring and non-flaring ARs derived from the multi-taper method (MTM) spectrum and wavelet scalograms are quite different as well, and they vary from one solar cycle to another. The largest detected period in flaring ARs is 113± 1.6 days while we detected much longer periodicities (327± 13, 312 ± 11, and 256± 8 days) in the non-flaring AR profiles. No meaningful periodicities were detected in the MTM spectrum of flaring ARs exceeding 55± 0.7 days during Solar Cycles 22 and 24, while a 113± 1.3 days period was detected in flaring ARs of Solar Cycle 23. For the non-flaring ARs the largest detected period was only 31± 0.2 days for Cycle 22 and 72± 1.3 days for the current Cycle 24, while the largest measured period was 327± 13 days during Solar Cycle 23.

Menstrual characteristics and night work among nurses.

Science.gov (United States)

Moen, Bente E; Baste, Valborg; Morken, Tone; Alsaker, Kjersti; Pallesen, Ståle; Bjorvatn, Bjørn

2015-01-01

Night work has been associated with adverse effects in terms of reproductive health. Specifically, menstruation has been suggested to be negatively impacted by night work, which again may influence fertility. This study investigated whether working nights is related to menstrual characteristics and if there is a relationship between shift work disorder (SWD) and menstruation. The study was cross-sectional, response rate 38%. The sample comprised female nurses who were members of the Norwegian Nurses Association; below 50 yr of age, who were not pregnant, did not use hormonal pills or intrauterine devices and who had not reached menopause (n=766). The nurses answered a postal survey including questions about night work and menstrual characteristics. Fifteen per cent reported to have irregular menstruations. Thirty-nine per cent of the nurses were classified as having SWD. Logistic regression analyses concerning the relationship between irregular menstruations and night work did not show any associations. Furthermore, no associations were found between cycle length or bleeding period and night work parameters. No associations were found between menstrual characteristics and SWD.

Cluster headache in women: relation with menstruation, use of oral contraceptives, pregnancy, and menopause

Science.gov (United States)

van Vliet, J A; Favier, I; Helmerhorst, F M; Haan, J; Ferrari, M D

2006-01-01

In contrast with migraine, little is known about the relation between cluster headache and menstrual cycle, oral contraceptives, pregnancy, and menopause. A population based questionnaire study was performed among 224 female cluster headache patients, and the possible effect of hormonal influences on cluster headache attacks studied. For control data, a similar but adjusted questionnaire was sent to healthy volunteers and migraine patients. It was found that menstruation, use of oral contraceptives, pregnancy, and menopause had a much smaller influence on cluster headache attacks than in migraine. Cluster headache can, however, have a large impact on individual women, for example to refrain from having children. PMID:16407458

ECG-gated interventional cardiac reconstruction for non-periodic motion.

Science.gov (United States)

Rohkohl, Christopher; Lauritsch, Günter; Biller, Lisa; Hornegger, Joachim

2010-01-01

The 3-D reconstruction of cardiac vasculature using C-arm CT is an active and challenging field of research. In interventional environments patients often do have arrhythmic heart signals or cannot hold breath during the complete data acquisition. This important group of patients cannot be reconstructed with current approaches that do strongly depend on a high degree of cardiac motion periodicity for working properly. In a last year's MICCAI contribution a first algorithm was presented that is able to estimate non-periodic 4-D motion patterns. However, to some degree that algorithm still depends on periodicity, as it requires a prior image which is obtained using a simple ECG-gated reconstruction. In this work we aim to provide a solution to this problem by developing a motion compensated ECG-gating algorithm. It is built upon a 4-D time-continuous affine motion model which is capable of compactly describing highly non-periodic motion patterns. A stochastic optimization scheme is derived which minimizes the error between the measured projection data and the forward projection of the motion compensated reconstruction. For evaluation, the algorithm is applied to 5 datasets of the left coronary arteries of patients that have ignored the breath hold command and/or had arrhythmic heart signals during the data acquisition. By applying the developed algorithm the average visibility of the vessel segments could be increased by 27%. The results show that the proposed algorithm provides excellent reconstruction quality in cases where classical approaches fail. The algorithm is highly parallelizable and a clinically feasible runtime of under 4 minutes is achieved using modern graphics card hardware.

Relationship of Level of Functioning of Institutionalized Women on a Task Analysis of Personal Care for Menstruation and the Adaptive Behavior Scale.

Science.gov (United States)

Brekke, Beverly W.; And Others

A 40-item behavior analysis task, the Menstrual Care Scale, was developed and tested with 75 randomly selected institutionalized severely retarded women (13-59 years old). The need for developing personal care skills in menstruation habits had been identified as a priority area for sexuality instruction by staff and confirmed by analysis of…

A HISTOPATHOLOGICAL STUDY OF NON-NEOPLASTIC AND NEOPLASTIC LESIONS OF KIDNEY FOR A PERIOD OF TWO YEARS

Directory of Open Access Journals (Sweden)

Jagadeeswari Suvvari

2018-01-01

Full Text Available BACKGROUND Nephrectomy is a common procedure in surgical practice. There are many indications for nephrectomy, non-neoplastic and neoplastic conditions. The common conditions being chronic pyelonephritis and renal tumours. A detailed and meticulous histopathological examination is essential to establish the diagnosis of lesions of kidney. MATERIALS AND METHODS It is a retrospective study for a period of two years from January 2015 to December 2016 at a tertiary care centre. 34 cases of nephrectomy specimens were analysed and data recorded. RESULTS Non-neoplastic lesions were constituting 47.05% (16 of cases and 52.94% (18 cases were neoplastic lesions. Lesions were more common in females with male:female ratio of 1:1.4. Both the lesions were common in age group of 41-50 years. CONCLUSION The prevalence of neoplastic lesions was more common than non-neoplastic lesions. The commonest indication for nephrectomy was chronic pyelonephritis followed by renal tumours. Histopathological examination in correlation with clinical and radiological features plays a great role in subcategorisation of lesions accurately to ensure better therapy.

Goserelin with chemotherapy to preserve ovarian function in pre-menopausal women with early breast cancer: menstruation and pregnancy outcomes.

Science.gov (United States)

Wong, M; O'Neill, S; Walsh, G; Smith, I E

2013-01-01

Premature ovarian failure and infertility following chemotherapy in early breast cancer (EBC) are major concerns for young women. The role of gonadotrophin-releasing hormone (GnRH) agonists with chemotherapy in EBC in reducing the incidence of chemotherapy-induced early menopause remains uncertain, and long-term data on the recovery of fertility are sparse. We report an audit of our experience with the GnRH agonist, goserelin (Zoladex®), used with chemotherapy to preserve ovarian function and maintain fertility. Pre-menopausal women were given goserelin subcutaneously every 28 days during chemotherapy, starting 0-14 days before treatment. The main clinical end point was recovery of menstruation after chemotherapy. The other end points were rate of successful conception and median time to recovery of menses. About 84% of 125 women recovered menstruation with the median time to recovery of 6 months (1-43 months), including 76% of 71 patients aged over 35. Of the 42 patients who attempted pregnancy, 71% (n=30) managed to achieve pregnancies. At the time of analysis, there were 42 pregnancies and 30 healthy deliveries. The GnRH agonist, goserelin, given with chemotherapy for EBC is associated with a low risk of long-term chemotherapy-induced amenorrhoea and a high chance of pregnancy. Further randomised trials are needed.

Stability of periodic steady-state solutions to a non-isentropic Euler-Poisson system

Science.gov (United States)

Liu, Cunming; Peng, Yue-Jun

2017-06-01

We study the stability of periodic smooth solutions near non-constant steady-states for a non-isentropic Euler-Poisson system without temperature damping term. The system arises in the theory of semiconductors for which the doping profile is a given smooth function. In this stability problem, there are no special restrictions on the size of the doping profile, but only on the size of the perturbation. We prove that small perturbations of periodic steady-states are exponentially stable for large time. For this purpose, we introduce new variables and choose a non-diagonal symmetrizer of the full Euler equations to recover dissipation estimates. This also allows to make the proof of the stability result very simple and concise.

Menstrual Characteristics and Related Problems in 9-18 Year- Old Turkish School Girls.

Science.gov (United States)

Yücel, Gül; Kendirci, Mustafa; Gül, Ülkü

2018-03-14

To determine the cross-sectional characteristics of menstruating girls, dysmenorrhea and the frequencies of related problems. Descripitive, cross-sectional study. Randomly selected primary, junior and high schools in the city center of Kayseri. 2000 female adolescents of ages between 9 and 18 years. We used a questionnaire addressing the epidemiological characteristics of menstruation, such as age at menarche, duration of menstrual intervals, average days of bleeding, and any menstrual problems and their frequencies. This study consists of a sufficient number of participants from all age groups. Of the participant (n= 2000) girls, 63.7% (n: 1274) had started menstruating. The mean age at menarche was 12.74 ± 1.03 years. With a prevalence of 84.8% (n: 1080), dysmenorrhea was the most prevalent menstrual problem and the average pain score was 5.87 ± 2.45. Of the menstruating girls, 34% (n: 439) used painkillers, the most commonly used was acetaminophen; during their period the prevalence of non-medical methods to relieve pain was % 35.2; the rate of seeking medical help for dysmenorrhea was 9.3 % (n: 119). In menstruating participants, 90.8 % was discussed their menstrual problems with their mothers. The rate of school absenteeism in menstruating girls was 15.9 % in general and 18 % in those with dysmenorrhea. Problems related to menstruation are common in adolescents and these problems affect their social life. In adolescent girls, the most common menstrual problem is dysmenorrhea and it affects school performance and attendance. Girls with menstrual problems showed a low rate of seeking medical help. Copyright © 2018. Published by Elsevier Inc.

Steroids Regulate CXCL4 in the Human Endometrium During Menstruation to Enable Efficient Endometrial Repair.

Science.gov (United States)

Maybin, Jacqueline A; Thiruchelvam, Uma; Madhra, Mayank; Saunders, Philippa T K; Critchley, Hilary O D

2017-06-01

Repair of the endometrial surface at menstruation must be efficient to minimize blood loss and optimize reproductive function. The mechanism and regulation of endometrial repair remain undefined. To determine the presence/regulation of CXCL4 in the human endometrium as a putative repair factor at menses. Endometrial tissue was collected throughout the menstrual cycle from healthy women attending the gynecology department. Menstrual blood loss was objectively measured in a subset, and heavy menstrual bleeding (HMB) was defined as >80 mL per cycle. Monocytes were isolated from peripheral blood. CXCL4 messenger RNA (mRNA) and protein were identified by quantitative reverse transcription polymerase chain reaction and immunohistochemistry. The function/regulation of endometrial CXCL4 was explored by in vitro cell culture. CXCL4 mRNA concentrations were significantly increased during menstruation. Intense staining for CXCL4 was detected in late secretory and menstrual tissue, localized to stromal, epithelial and endothelial cells. Colocalization identified positive staining in CD68+ macrophages. Treatment of human endometrial stromal and endothelial cells (hESCs and HEECs, respectively) with steroids revealed differential regulation of CXCL4. Progesterone withdrawal resulted in significant increases in CXCL4 mRNA and protein in hESCs, whereas cortisol significantly increased CXCL4 in HEECs. In women with HMB, CXCL4 was reduced in endothelial cells during the menstrual phase compared with women with normal menstrual bleeding. Cortisol-exposed macrophages displayed increased chemotaxis toward CXCL4 compared with macrophages incubated with estrogen or progesterone. These data implicate CXCL4 in endometrial repair after menses. Reduced cortisol at the time of menses may contribute to delayed endometrial repair and HMB, in part by mechanisms involving aberrant expression of CXCL4. Copyright © 2017 by the Endocrine Society

Denjoy minimal sets and Birkhoff periodic orbits for non-exact monotone twist maps

Science.gov (United States)

Qin, Wen-Xin; Wang, Ya-Nan

2018-06-01

A non-exact monotone twist map φbarF is a composition of an exact monotone twist map φ bar with a generating function H and a vertical translation VF with VF ((x , y)) = (x , y - F). We show in this paper that for each ω ∈ R, there exists a critical value Fd (ω) ≥ 0 depending on H and ω such that for 0 ≤ F ≤Fd (ω), the non-exact twist map φbarF has an invariant Denjoy minimal set with irrational rotation number ω lying on a Lipschitz graph, or Birkhoff (p , q)-periodic orbits for rational ω = p / q. Like the Aubry-Mather theory, we also construct heteroclinic orbits connecting Birkhoff periodic orbits, and show that quasi-periodic orbits in these Denjoy minimal sets can be approximated by periodic orbits. In particular, we demonstrate that at the critical value F =Fd (ω), the Denjoy minimal set is not uniformly hyperbolic and can be approximated by smooth curves.

Post-Irradiation Non-Destructive Analyses of the AFIP-7 Experiment

Science.gov (United States)

Williams, W. J.; Robinson, A. B.; Rabin, B. H.

2017-12-01

This article reports the results and interpretation of post-irradiation non-destructive examinations performed on four curved full-size fuel plates that comprise the AFIP-7 experiment. These fuel plates, having a U-10 wt.%Mo monolithic design, were irradiated under moderate operating conditions in the Advanced Test Reactor to assess fuel performance for geometries that are prototypic of research reactor fuel assemblies. Non-destructive examinations include visual examination, neutron radiography, profilometry, and precision gamma scanning. This article evaluates the qualitative and quantitative data taken for each plate, compares corresponding data sets, and presents the results of swelling analyses. These characterization results demonstrate that the fuel meets established irradiation performance requirements for mechanical integrity, geometric stability, and stable and predictable behavior.

Periodic travelling and non-travelling wave solutions of the nonlinear Klein-Gordon equation with imaginary mass

International Nuclear Information System (INIS)

Tang Xiaoyan; Shukla, Padma Kant

2008-01-01

Exact solutions, including the periodic travelling and non-travelling wave solutions, are presented for the nonlinear Klein-Gordon equation with imaginary mass. Some arbitrary functions are permitted in the periodic non-travelling wave solutions, which contribute to various high dimensional nonlinear structures

Stochastic sensitivity analysis of periodic attractors in non-autonomous nonlinear dynamical systems based on stroboscopic map

Energy Technology Data Exchange (ETDEWEB)

Guo, Kong-Ming, E-mail: kmguo@xidian.edu.cn [School of Electromechanical Engineering, Xidian University, P.O. Box 187, Xi' an 710071 (China); Jiang, Jun, E-mail: jun.jiang@mail.xjtu.edu.cn [State Key Laboratory for Strength and Vibration, Xi' an Jiaotong University, Xi' an 710049 (China)

2014-07-04

To apply stochastic sensitivity function method, which can estimate the probabilistic distribution of stochastic attractors, to non-autonomous dynamical systems, a 1/N-period stroboscopic map for a periodic motion is constructed in order to discretize the continuous cycle into a discrete one. In this way, the sensitivity analysis of a cycle for discrete map can be utilized and a numerical algorithm for the stochastic sensitivity analysis of periodic solutions of non-autonomous nonlinear dynamical systems under stochastic disturbances is devised. An external excited Duffing oscillator and a parametric excited laser system are studied as examples to show the validity of the proposed method. - Highlights: • A method to analyze sensitivity of stochastic periodic attractors in non-autonomous dynamical systems is proposed. • Probabilistic distribution around periodic attractors in an external excited Φ{sup 6} Duffing system is obtained. • Probabilistic distribution around a periodic attractor in a parametric excited laser system is determined.

The role of decidual cells in uterine hemostasis, menstruation, inflammation, adverse pregnancy outcomes and abnormal uterine bleeding.

Science.gov (United States)

Schatz, Frederick; Guzeloglu-Kayisli, Ozlem; Arlier, Sefa; Kayisli, Umit A; Lockwood, Charles J

2016-06-01

Human pregnancy requires robust hemostasis to prevent hemorrhage during extravillous trophoblast (EVT) invasion of the decidualized endometrium, modification of spiral arteries and post-partum processes. However, decidual hemorrhage (abruption) can occur throughout pregnancy from poorly transformed spiral arteries, causing fetal death or spontaneous preterm birth (PTB), or it can promote the aberrant placentation observed in intrauterine growth restriction (IUGR) and pre-eclampsia; all leading causes of perinatal or maternal morbidity and mortality. In non-fertile cycles, the decidua undergoes controlled menstrual bleeding. Abnormal uterine bleeding (AUB) accompanying progestin-only, long-acting, reversible contraception (pLARC) accounts for most discontinuations of these safe and highly effective agents, thereby contributing to unwanted pregnancies and abortion. The aim of this study was to investigate the role of decidual cells in uterine hemostasis, menstruation, inflammation, adverse pregnancy outcomes and abnormal uterine bleeding. We conducted a critical review of the literature arising from PubMed searches up to December 2015, regarding in situ and in vitro expression and regulation of several specific proteins involved in uterine hemostasis in decidua and cycling endometrium. In addition, we discussed clinical and molecular mechanisms associated with pLARC-induced AUB and pregnancy complications with abruptions, chorioamnionitis or pre-eclampsia. Progestin-induced decidualization of estradiol-primed human endometrial stromal cells (HESCs) increases in vivo and in vitro expression of tissue factor (TF) and type-1 plasminogen activator inhibitor (PAI-1) while inhibiting plasminogen activators (PAs), matrix metalloproteinases (MMPs), and the vasoconstrictor, endothelin-1 (ET-1). These changes in decidual cell-derived regulators of hemostasis, fibrinolysis, extracellular matrix (ECM) turnover, and vascular tone prevent hemorrhage during EVT invasion and

Material model for non-linear finite element analyses of large concrete structures

NARCIS (Netherlands)

Engen, Morten; Hendriks, M.A.N.; Øverli, Jan Arve; Åldstedt, Erik; Beushausen, H.

2016-01-01

A fully triaxial material model for concrete was implemented in a commercial finite element code. The only required input parameter was the cylinder compressive strength. The material model was suitable for non-linear finite element analyses of large concrete structures. The importance of including

Non-periodic pseudo-random numbers used in Monte Carlo calculations

Science.gov (United States)

Barberis, Gaston E.

2007-09-01

The generation of pseudo-random numbers is one of the interesting problems in Monte Carlo simulations, mostly because the common computer generators produce periodic numbers. We used simple pseudo-random numbers generated with the simplest chaotic system, the logistic map, with excellent results. The numbers generated in this way are non-periodic, which we demonstrated for 1013 numbers, and they are obtained in a deterministic way, which allows to repeat systematically any calculation. The Monte Carlo calculations are the ideal field to apply these numbers, and we did it for simple and more elaborated cases. Chemistry and Information Technology use this kind of simulations, and the application of this numbers to quantum Monte Carlo and cryptography is immediate. I present here the techniques to calculate, analyze and use these pseudo-random numbers, show that they lack periodicity up to 1013 numbers and that they are not correlated.

Non-periodic pseudo-random numbers used in Monte Carlo calculations

International Nuclear Information System (INIS)

Barberis, Gaston E.

2007-01-01

The generation of pseudo-random numbers is one of the interesting problems in Monte Carlo simulations, mostly because the common computer generators produce periodic numbers. We used simple pseudo-random numbers generated with the simplest chaotic system, the logistic map, with excellent results. The numbers generated in this way are non-periodic, which we demonstrated for 10 13 numbers, and they are obtained in a deterministic way, which allows to repeat systematically any calculation. The Monte Carlo calculations are the ideal field to apply these numbers, and we did it for simple and more elaborated cases. Chemistry and Information Technology use this kind of simulations, and the application of this numbers to quantum Monte Carlo and cryptography is immediate. I present here the techniques to calculate, analyze and use these pseudo-random numbers, show that they lack periodicity up to 10 13 numbers and that they are not correlated

Non-periodic inspection optimization of multi-component and k-out-of-m systems

International Nuclear Information System (INIS)

Hajipour, Yassin; Taghipour, Sharareh

2016-01-01

This paper proposes a model to find the optimal non-periodic inspection interval over a finite planning horizon for two types of multi-component repairable systems. The first system contains hard-type and soft-type components, and the second system is a k-out-of-m system with m identical components. The failures of components in both systems follow a non-homogeneous Poisson process. A component can be a single part such as battery or line cord, or a subsystem, such as circuit breaker or charger in an infusion pump, which depending on their failures could be either replaced or minimally repaired according to their ages at failure. The systems are inspected at scheduled inspections or when an event of opportunistic inspection or a system failure occur. We develop a model to find the optimal inspection scheme for each system, which results in the minimum total expected cost over the system's lifecycle. We first develop a simulation model to obtain the total expected cost for a given non-periodic inspection scheme, and then integrate the simulation model with a genetic algorithm to obtain the optimal scheme more efficiently. - Highlights: • Non-periodic inspection optimization of two complex systems. • One system consists of soft-type and hard-type components. • The second system is a k-out-of-m system. • Integration of a simulation model and the genetic algorithm. • The model can be used when inspection is challenging or costly.

Detailed clinical and molecular study of 20 females with Xq deletions with special reference to menstruation and fertility.

Science.gov (United States)

Mercer, Catherine L; Lachlan, Katherine; Karcanias, Alexandra; Affara, Nabeel; Huang, Shuwen; Jacobs, Patricia A; Thomas, N Simon

2013-01-01

Integrity of the long arm of the X chromosome is important for maintaining female fertility and several critical regions for normal ovarian function have been proposed. In order to understand further the importance of specific areas of the X chromosome, we describe a series of 20 previously unreported patients missing part of Xq in whom detailed phenotypic information has been gathered as well as precise chromosome mapping using array Comparative Genomic Hybridization. Features often associated with Turner syndrome were not common in our study and excluding puberty, menarche and menstruation, the phenotypes observed were present in only a minority of women and were not specific to the X chromosome. The most frequently occurring phenotypic features in our patients were abnormalities of menstruation and fertility. Larger terminal deletions were associated with a higher incidence of primary ovarian failure, occurring at a younger age; however patients with similar or even identical deletions had discordant menstrual phenotypes, making accurate genetic counselling difficult. Nevertheless, large deletions are likely to be associated with complete skewing of X inactivation so that the resulting phenotypes are relatively benign given the amount of genetic material missing, even in cases with unbalanced X;autosome translocations. Some degree of ovarian dysfunction is highly likely, especially for terminal deletions extending proximal to Xq27. In conjunction with patient data from the literature, our study suggests that loss of Xq26-Xq28 has the most significant effect on ovarian function. Copyright © 2012 Elsevier Masson SAS. All rights reserved.

Structural Dynamic Analyses And Test Predictions For Spacecraft Structures With Non-Linearities

Science.gov (United States)

Vergniaud, Jean-Baptiste; Soula, Laurent; Newerla, Alfred

2012-07-01

The overall objective of the mechanical development and verification process is to ensure that the spacecraft structure is able to sustain the mechanical environments encountered during launch. In general the spacecraft structures are a-priori assumed to behave linear, i.e. the responses to a static load or dynamic excitation, respectively, will increase or decrease proportionally to the amplitude of the load or excitation induced. However, past experiences have shown that various non-linearities might exist in spacecraft structures and the consequences of their dynamic effects can significantly affect the development and verification process. Current processes are mainly adapted to linear spacecraft structure behaviour. No clear rules exist for dealing with major structure non-linearities. They are handled outside the process by individual analysis and margin policy, and analyses after tests to justify the CLA coverage. Non-linearities can primarily affect the current spacecraft development and verification process on two aspects. Prediction of flights loads by launcher/satellite coupled loads analyses (CLA): only linear satellite models are delivered for performing CLA and no well-established rules exist how to properly linearize a model when non- linearities are present. The potential impact of the linearization on the results of the CLA has not yet been properly analyzed. There are thus difficulties to assess that CLA results will cover actual flight levels. Management of satellite verification tests: the CLA results generated with a linear satellite FEM are assumed flight representative. If the internal non- linearities are present in the tested satellite then there might be difficulties to determine which input level must be passed to cover satellite internal loads. The non-linear behaviour can also disturb the shaker control, putting the satellite at risk by potentially imposing too high levels. This paper presents the results of a test campaign performed in

On Rigorous Drought Assessment Using Daily Time Scale: Non-Stationary Frequency Analyses, Revisited Concepts, and a New Method to Yield Non-Parametric Indices

Directory of Open Access Journals (Sweden)

Charles Onyutha

2017-10-01

Full Text Available Some of the problems in drought assessments are that: analyses tend to focus on coarse temporal scales, many of the methods yield skewed indices, a few terminologies are ambiguously used, and analyses comprise an implicit assumption that the observations come from a stationary process. To solve these problems, this paper introduces non-stationary frequency analyses of quantiles. How to use non-parametric rescaling to obtain robust indices that are not (or minimally skewed is also introduced. To avoid ambiguity, some concepts on, e.g., incidence, extremity, etc., were revisited through shift from monthly to daily time scale. Demonstrations on the introduced methods were made using daily flow and precipitation insufficiency (precipitation minus potential evapotranspiration from the Blue Nile basin in Africa. Results show that, when a significant trend exists in extreme events, stationarity-based quantiles can be far different from those when non-stationarity is considered. The introduced non-parametric indices were found to closely agree with the well-known standardized precipitation evapotranspiration indices in many aspects but skewness. Apart from revisiting some concepts, the advantages of the use of fine instead of coarse time scales in drought assessment were given. The links for obtaining freely downloadable tools on how to implement the introduced methods were provided.

Influence of Diet, Menstruation and Genetic Factors on Iron Status: A Cross-Sectional Study in Spanish Women of Childbearing Age

Directory of Open Access Journals (Sweden)

Ruth Blanco-Rojo

2014-03-01

Full Text Available The aim of this study was to investigate the combined influence of diet, menstruation and genetic factors on iron status in Spanish menstruating women (n = 142. Dietary intake was assessed by a 72-h detailed dietary report and menstrual blood loss by a questionnaire, to determine a Menstrual Blood Loss Coefficient (MBLC. Five selected SNPs were genotyped: rs3811647, rs1799852 (Tf gene; rs1375515 (CACNA2D3 gene; and rs1800562 and rs1799945 (HFE gene, mutations C282Y and H63D, respectively. Iron biomarkers were determined and cluster analysis was performed. Differences among clusters in dietary intake, menstrual blood loss parameters and genotype frequencies distribution were studied. A categorical regression was performed to identify factors associated with cluster belonging. Three clusters were identified: women with poor iron status close to developing iron deficiency anemia (Cluster 1, n = 26; women with mild iron deficiency (Cluster 2, n = 59 and women with normal iron status (Cluster 3, n = 57. Three independent factors, red meat consumption, MBLC and mutation C282Y, were included in the model that better explained cluster belonging (R2 = 0.142, p < 0.001. In conclusion, the combination of high red meat consumption, low menstrual blood loss and the HFE C282Y mutation may protect from iron deficiency in women of childbearing age. These findings could be useful to implement adequate strategies to prevent iron deficiency anemia.

Influence of diet, menstruation and genetic factors on iron status: a cross-sectional study in Spanish women of childbearing age.

Science.gov (United States)

Blanco-Rojo, Ruth; Toxqui, Laura; López-Parra, Ana M; Baeza-Richer, Carlos; Pérez-Granados, Ana M; Arroyo-Pardo, Eduardo; Vaquero, M Pilar

2014-03-06

The aim of this study was to investigate the combined influence of diet, menstruation and genetic factors on iron status in Spanish menstruating women (n = 142). Dietary intake was assessed by a 72-h detailed dietary report and menstrual blood loss by a questionnaire, to determine a Menstrual Blood Loss Coefficient (MBLC). Five selected SNPs were genotyped: rs3811647, rs1799852 (Tf gene); rs1375515 (CACNA2D3 gene); and rs1800562 and rs1799945 (HFE gene, mutations C282Y and H63D, respectively). Iron biomarkers were determined and cluster analysis was performed. Differences among clusters in dietary intake, menstrual blood loss parameters and genotype frequencies distribution were studied. A categorical regression was performed to identify factors associated with cluster belonging. Three clusters were identified: women with poor iron status close to developing iron deficiency anemia (Cluster 1, n = 26); women with mild iron deficiency (Cluster 2, n = 59) and women with normal iron status (Cluster 3, n = 57). Three independent factors, red meat consumption, MBLC and mutation C282Y, were included in the model that better explained cluster belonging (R2 = 0.142, p < 0.001). In conclusion, the combination of high red meat consumption, low menstrual blood loss and the HFE C282Y mutation may protect from iron deficiency in women of childbearing age. These findings could be useful to implement adequate strategies to prevent iron deficiency anemia.

Prevalence and severity of dysmenorrhea: a problem related to menstruation, among first and second year female medical students.

Science.gov (United States)

Singh, Amita; Kiran, Dukhu; Singh, Harminder; Nel, Bithika; Singh, Prabhakar; Tiwari, Pavan

2008-01-01

Dysmenorrhea is the most common of gynecologic complaints. It affects half of all female adolescents today and represents the leading cause of periodic college/school absenteeism among that population. To evaluate the menstrual problem specially dysmenorrhea and its severity in female medical students and its effect on their regular activities. This is a cross-sectional descriptive study; conducted on 107 female medical students, all participants were given a questionnaire to complete; questions were related to menstruation elucidating variations in menstrual patterns, history of dysmenorrhea and its severity, pre-menstrual symptom and absenteeism from college and/or class; to detect the severity of dysmenorrhea we used the verbal multi-dimensional scoring system, participants were given 20 minutes to complete the questionnaire. The mean age of subjects at menarche was 12.5 (+/-1.52) years, with a range of 10-15 years. The prevalence of dysmenorrhea was 73.83%; approximately 4.67% of dysmenorrhic subjects had severe dysmenorrhea. The average duration between two periods and the duration of menstrual flow were 28.34 (+/-7.54) days and 4.5 (+/-2.45) days respectively. Prevalence of other menstrual disorders like irregularity, prolonged menstrual bleeding, heavy menstrual bleeding and PCOD were 7.47%, 10.28%, 23.36% and 3.73% respectively. Among female medical students who reported dysmenorrhea; 31.67% and 8.68% were frequently missing college & classes respectively. Premenstrual symptom was the second most (60.50%) prevalent disorder and 67.08% reported social withdrawal. Dysmenorrhea and PMS is highly prevalent among female medical students, it is related to college/class absenteeism, limitations on social, academic, sports and daily activities. Maximum participants do not seek medical advice and self treat themselves with prostaglandin inhibitors; like Ibuprofen.

Comparative Evaluation of the Effect of Menstruation, Pregnancy and Menopause on Salivary Flow Rate, pH and Gustatory Function.

Science.gov (United States)

Saluja, Pulin; Shetty, Vishwaprakash; Dave, Aparna; Arora, Manpreet; Hans, Vibha; Madan, Ajay

2014-10-01

There are five situations in a women's life during which hormone fluctuations make them more susceptible to oral health problems - during puberty, at certain points in the monthly menstrual cycle, when using birth control pills, during pregnancy, and at menopause. The present study aimed at evaluating the effect of menstruation, pregnancy and menopause on salivary flow rate, pH and gustatory function. The study was carried out on 120 patients including 30 controls (with normal menstrual cycle of 28 to 30 d) and 90 cases (30 patients within three days of menstruation, 30 pregnant and 30 postmenopausal). Paraffin-stimulated saliva samples were obtained by expectoration to calculate salivary flow rate, pH was measured electrometically and patients were prospectively evaluated for gustatory function. Then, whole mouth taste test was performed in which the quality identification and intensity ratings of taste solutions were measured. No statistically significant difference was found between the groups with respect to salivary flow rate but pH values were significantly lower in post menopausal women (pwomen than intensity of taste perception for other tastes (pwomen reported change in their dietary habits as all of them expressed liking for sweeter food. Reduced salivary flow rate and pH in postmen-opausal women may make them more prone to the occurrence of oral health problems. Also, pregnant and postmenopausal women appeared to have a reduced perception of sucrose, which can alter eating habits, such as intake of more sweet foods whereas no significant difference is observed in taste perception of NaCl, citric acid and quinine hydrochloride between the subjects.

Managing menstruation in the workplace: an overlooked issue in low- and middle-income countries.

Science.gov (United States)

Sommer, Marni; Chandraratna, Sahani; Cavill, Sue; Mahon, Therese; Phillips-Howard, Penelope

2016-06-06

The potential menstrual hygiene management barriers faced by adolescent girls and women in workplace environments in low- and middle-income countries has been under addressed in research, programming and policy. Despite global efforts to reduce poverty among women in such contexts, there has been insufficient attention to the water and sanitation related barriers, specifically in relation to managing monthly menstruation, that may hinder girls' and women's contributions to the workplace, and their health and wellbeing. There is an urgent need to document the specific social and environmental barriers they may be facing in relation to menstrual management, to conduct a costing of the implications of inadequate supportive workplace environments for menstrual hygiene management, and to understand the implications for girls' and women's health and wellbeing. This will provide essential evidence for guiding national policy makers, the private sector, donors and activists focused on advancing girls' and women's rights.

Levee reliability analyses for various flood return periods - a case study in southern Taiwan

Science.gov (United States)

Huang, W.-C.; Yu, H.-W.; Weng, M.-C.

2015-04-01

In recent years, heavy rainfall conditions have caused disasters around the world. To prevent losses by floods, levees have often been constructed in inundation-prone areas. This study performed reliability analyses for the Chiuliao First Levee in southern Taiwan. The failure-related parameters were the water level, the scouring depth, and the in situ friction angle. Three major failure mechanisms were considered: the slope sliding failure of the levee and the sliding and overturning failures of the retaining wall. When the variability of the in situ friction angle and the scouring depth are considered for various flood return periods, the variations of the factor of safety for the different failure mechanisms show that the retaining wall sliding and overturning failures are more sensitive to the change of the friction angle. When the flood return period is greater than 2 years, the levee could fail with slope sliding for all values of the water level difference. The results of levee stability analysis considering the variability of different parameters could aid engineers in designing the levee cross sections, especially with potential failure mechanisms in mind.

Fourier analysis in dynamic non periodic phenomena in nuclear medicine

International Nuclear Information System (INIS)

Constantinesco, A.; Lallot, C.

1984-01-01

The success of Fourier analysis in assessing cardiac function has led us to investigate other possible uses of this technique. We show that phase analysis applied to dynamic non periodic activity changes gives useful parametric functional images. The phase image is comparable to a transit time image, the amplitude image is comparable to the maximum variations of activity and the mean image corresponds to a normalized sum of images. Exemples of this powerful application of Fourier analysis are discussed [fr

Faktor-Faktor yang Mempengaruhi Financial Sustainability Ratio pada Bank Umum Swast Nasional Non Devisa Periode 1995-2005

Directory of Open Access Journals (Sweden)

Luciana Spica Almilia

2009-01-01

Full Text Available This study is aimed to test the consistency of time period model, whether the information that previously affects today’s performance can be used to predict the performance in the future, and how the consistency of Indonesia banking financial prediction model formulation equation in order to detect bank condition and performance in the period of pre-economic crisis (1995-1996, during economic crisis (1997-1999 or post-economic crisis (2000-2005 is since bank condition and health is the interest of all relevant parties namely bank owner and manager, customers, Bank Indonesia in its capacity as the supervisor and builder, and the government. The samples are Non Foreign Exchange National Private Banks listed in Indonesian Banking Directory during the period after economic crisis in 1995 – 2005 and Indonesian Financial Economic Statistics Monthly Statement for economic macro indicator. The sampling is performed by means of purposive method (purposive sampling. Dependent Variable in this study is Financial Sustainability Ratio and independent variable in this study is Capital Adequacy Ratio, Non Performing Loan, Return On Assets, Operational Cost Ratio to Operational Income, Loan to Deposit Ratio, Money Supply Sensitivity, General Customer Price Index Sensitivity and SBI Interest Rate Sensitivity. The result of this study shows that model financial sustainability ratio did not have structural stabilization in 1999 – 2005. Abstract in Bahasa Indonesia: Penelitian ini betujuan untuk menguji konsistensi model prediksi kinerja keuangan pada Bank Umum Swasta Nasional Non Devisa periode 1995-2005. Variabel-variabel yang digunakan dalam penelitian ini adalah kinerja keuangan Bank Umum Swasta Nasional Non Devisa yang diproksikan melalui Financial Sustainability Ratio (FSR. Sampel yang terpilih dalam penelitian ini dengan metode purposive sampling berjumlah 28 bank umum swasta nasional non devisa yang terdaftar di direktori Bank Indonesia selama tahun

Evolution of periodicity in periodical cicadas.

Science.gov (United States)

Ito, Hiromu; Kakishima, Satoshi; Uehara, Takashi; Morita, Satoru; Koyama, Takuya; Sota, Teiji; Cooley, John R; Yoshimura, Jin

2015-09-14

Periodical cicadas (Magicicada spp.) in the USA are famous for their unique prime-numbered life cycles of 13 and 17 years and their nearly perfectly synchronized mass emergences. Because almost all known species of cicada are non-periodical, periodicity is assumed to be a derived state. A leading hypothesis for the evolution of periodicity in Magicicada implicates the decline in average temperature during glacial periods. During the evolution of periodicity, the determinant of maturation in ancestral cicadas is hypothesized to have switched from size dependence to time (period) dependence. The selection for the prime-numbered cycles should have taken place only after the fixation of periodicity. Here, we build an individual-based model of cicadas under conditions of climatic cooling to explore the fixation of periodicity. In our model, under cold environments, extremely long juvenile stages lead to extremely low adult densities, limiting mating opportunities and favouring the evolution of synchronized emergence. Our results indicate that these changes, which were triggered by glacial cooling, could have led to the fixation of periodicity in the non-periodical ancestors.

Non-linear vibrational modes in biomolecules: A periodic orbits description

International Nuclear Information System (INIS)

Kampanarakis, Alexandros; Farantos, Stavros C.; Daskalakis, Vangelis; Varotsis, Constantinos

2012-01-01

Graphical abstract: Vibrational frequency shifts in Fe IV = O species of the active site of cytochrome c oxidase are attributed to changes in the surrounding Coulomb field. Periodic orbits analysis assists to find the most anharmonic modes in model biomolecules. Highlights: ► Periodic orbits are extended to multidimensional potentials of biomolecules. ► Highly anharmonic vibrational modes and center-saddle bifurcations are detected. ► Vibrational frequencies shifts in Oxoferryl species of CcO are observed. - Abstract: The vibrational harmonic normal modes of a molecule, which are valid at energies close to an equilibrium point (a minimum, maximum or saddle of the potential energy surface), are extended by periodic orbits to high energies where anharmonicity and coupling of the degrees of freedom are significant. In this way the assignment of the spectra, and thus the extraction of dynamics in highly excited molecules, can be obtained. New vibrational modes emanating from bifurcations of periodic orbits and long living localized trajectories signal the birth and localization of new quantum states. In this article we review and further study non-linear vibrational modes for model biomolecules such as alanine dipeptide and the active site in the oxoferryl oxidation state of the enzyme cytochrome c oxidase. We locate periodic orbits which exhibit high anhamonicity and lead to center-saddle bifurcations. These modes are associated to an isomerization process in alanine dipeptide and to frequency shifts in the oxoferryl observed by modifying the Coulomb field around the Imidazole–Fe IV = O species.

Period doubling on a non-neutral magnetized electron beam

International Nuclear Information System (INIS)

Boswell, R.W.

1984-01-01

Low frequency oscillations on a non-neutral magnetized electron beam of very low density are investigated. A perturbation analysis of the slow mode of the rigid rotator equilibrium is developed to illustrate the nature of large amplitude fundamental mode oscillations. The results of this theoretical analysis show two important characteristics: firstly, as the perturbation amplitude is increasedthe waveform ceases to be purely sinusoidal and shows period doubling. Secondly, above a certain threshold, all harmonics of the wave grow and the wave breaks. The results of the former are compared with a simple electron beam experiment and are found to be in good qualitative agreement

Non-Almost Periodicity of Parallel Transports for Homogeneous Connections

International Nuclear Information System (INIS)

Brunnemann, Johannes; Fleischhack, Christian

2012-01-01

Let A be the affine space of all connections in an SU(2) principal fibre bundle over ℝ 3 . The set of homogeneous isotropic connections forms a line l in A. We prove that the parallel transports for general, non-straight paths in the base manifold do not depend almost periodically on l. Consequently, the embedding l ↪ A does not continuously extend to an embedding l-bar ↪ A-bar of the respective compactifications. Here, the Bohr compactification l-bar corresponds to the configuration space of homogeneous isotropic loop quantum cosmology and A-bar to that of loop quantum gravity. Analogous results are given for the anisotropic case.

Ideologies of sexuality, menstruation and risk: girls' experiences of puberty and schooling in northern Tanzania.

Science.gov (United States)

Sommer, Marni

2009-05-01

This paper examines girls' voiced experiences of menstruation, puberty and schooling in northern Tanzania. The study was conducted in Moshi and Rombo Districts of Kilimanjaro, a predominantly Chagga region with historically strong support for girls' education. The major question explored was how the onset of menses and puberty may be impacting on girls' school participation, given societal implications of pubertal onset and potentially gender discriminatory school environments. The methodology included a comparative case study using in-depth interviews and participatory research with young women living in urban and rural Kilimanjaro. Along with important findings about how menstrual onset creates challenges for girls attending school emerged findings about the significant gaps in girls' knowledge about body changes, sexual health and HIV/AIDS. These findings underline the importance of identifying new girl-centred approaches to guidance on bodily development and HIV prevention.

Therapeutic and Ethical Dilemma of Puberty and Menstruation Problems in an Intellectually Disabled (Autistic Female: a Case Report and Review of the Literature

Directory of Open Access Journals (Sweden)

Azadeh Memarian

2015-10-01

Full Text Available Intellectual disability is a term used when a person has certain limitations in mental functioning and skills. Autism is a group of developmental brain disorders, collectively called autism spectrum disorder (ASD. Teenagers with learning and physical disabilities are more likely to have menstrual problems compared to the general populations. The parents of a 12-year-old girl with autism spectrum disorder and intellectual disability referred to the coroner due to her numerous problems of puberty (menstruation including: poor hygiene and polluting herself and the environment, not allowing to put or change the pads and changes in mood and physical health prior period, requested for the surgery (hysterectomy. In legal medicine organization after reviewing the medical records, physical exams and medical consultations with a gynecologist and psychiatric, surgery was not accepted. Hysterectomy (surgery due to the age of the child, either physically or morally is not recommended. The use of hormone replacement therapy has side effects such as osteoporosis. In these cases, it seems noninvasive methods (behavioral therapy and learning care skills under the welfare experts is also more effective and morally.

Development of linear projecting in studies of non-linear flow. Acoustic heating induced by non-periodic sound

Energy Technology Data Exchange (ETDEWEB)

Perelomova, Anna [Gdansk University of Technology, Faculty of Applied Physics and Mathematics, ul. Narutowicza 11/12, 80-952 Gdansk (Poland)]. E-mail: anpe@mif.pg.gda.pl

2006-08-28

The equation of energy balance is subdivided into two dynamics equations, one describing evolution of the dominative sound, and the second one responsible for acoustic heating. The first one is the famous KZK equation, and the second one is a novel equation governing acoustic heating. The novel dynamic equation considers both periodic and non-periodic sound. Quasi-plane geometry of flow is supposed. Subdividing is provided on the base of specific links of every mode. Media with arbitrary thermic T(p,{rho}) and caloric e(p,{rho}) equations of state are considered. Individual roles of thermal conductivity and viscosity in the heating induced by aperiodic sound in the ideal gases and media different from ideal gases are discussed.

Development of linear projecting in studies of non-linear flow. Acoustic heating induced by non-periodic sound

Science.gov (United States)

Perelomova, Anna

2006-08-01

The equation of energy balance is subdivided into two dynamics equations, one describing evolution of the dominative sound, and the second one responsible for acoustic heating. The first one is the famous KZK equation, and the second one is a novel equation governing acoustic heating. The novel dynamic equation considers both periodic and non-periodic sound. Quasi-plane geometry of flow is supposed. Subdividing is provided on the base of specific links of every mode. Media with arbitrary thermic T(p,ρ) and caloric e(p,ρ) equations of state are considered. Individual roles of thermal conductivity and viscosity in the heating induced by aperiodic sound in the ideal gases and media different from ideal gases are discussed.

Development of linear projecting in studies of non-linear flow. Acoustic heating induced by non-periodic sound

International Nuclear Information System (INIS)

Perelomova, Anna

2006-01-01

The equation of energy balance is subdivided into two dynamics equations, one describing evolution of the dominative sound, and the second one responsible for acoustic heating. The first one is the famous KZK equation, and the second one is a novel equation governing acoustic heating. The novel dynamic equation considers both periodic and non-periodic sound. Quasi-plane geometry of flow is supposed. Subdividing is provided on the base of specific links of every mode. Media with arbitrary thermic T(p,ρ) and caloric e(p,ρ) equations of state are considered. Individual roles of thermal conductivity and viscosity in the heating induced by aperiodic sound in the ideal gases and media different from ideal gases are discussed

Instabilities in fluid layers and in reaction-diffusion systems: Steady states, time-periodic solutions, non-periodic attractors, and related convective and otherwise non-linear phenomena

Energy Technology Data Exchange (ETDEWEB)

Garcia Velarde, M

1977-07-01

Thermo convective instabilities in horizontal fluid layers are discussed with emphasis on the Rayleigh-Bernard model problem. Steady solutions and time-dependent phenomena (relaxation oscillations and transition to turbulence) are studied within the nonlinear Boussinesq-Oberbeck approximation. Homogeneous steady solutions, limit cycles, and inhomogeneous (ordered) spatial structures are also studied in simple reaction-diffusion systems. Lastly, the non-periodic attractor that appears at large Rayleigh numbers in the truncated Boussinesq-Oberbeck model of Lorenz, is constructed, and a discussion of turbulent behavior is given. (Author) 105 refs.

Instabilities in fluid layers and in reaction-diffusion systems: Steady states, time-periodic solutions, non-periodic attractors, and related convective and otherwise non-linear phenomena

International Nuclear Information System (INIS)

Garcia Velarde, M.

1977-01-01

Thermoconvective instabilities in horizontal fluid layers are discussed with emphasis on the Rayleigh-Benard model problem. Steady solutions and time-dependent phenomena (relaxation oscillations and transition to turbulence) are studied within the nonlinear Boussinesq-Oberbeck approximation. Homogeneous steady solutions, limit cycles, and inhomogeneous (ordered) spatial structures are also studied in simple reaction-diffusion systems. Lastly, the non-periodic attractor that appears at large Rayleigh numbers in the truncated Boussinesq-Oberbeck model of Lorenz, is constructed, and a discussion of turbulent behavior is given. (author) [es

Instabilities in fluid layers and in reaction-diffusion systems: Steady states, time-periodic solutions, non-periodic attractors, and related convective and otherwise non-linear phenomena

International Nuclear Information System (INIS)

Garcia Velarde, M.

1977-01-01

Thermo convective instabilities in horizontal fluid layers are discussed with emphasis on the Rayleigh-Bernard model problem. Steady solutions and time-dependent phenomena (relaxation oscillations and transition to turbulence) are studied within the nonlinear Boussinesq-Oberbeck approximation. Homogeneous steady solutions, limit cycles, and inhomogeneous (ordered) spatial structures are also studied in simple reaction-diffusion systems. Lastly, the non-periodic attractor that appears at large Rayleigh numbers in the truncated Boussinesq-Oberbeck model of Lorenz, is constructed, and a discussion of turbulent behavior is given. (Author) 105 refs

Non-linear finite element analyses applicable for the design of large reinforced concrete structures

NARCIS (Netherlands)

Engen, M; Hendriks, M.A.N.; Øverli, Jan Arve; Åldstedt, Erik

2017-01-01

In order to make non-linear finite element analyses applicable during assessments of the ultimate load capacity or the structural reliability of large reinforced concrete structures, there is need for an efficient solution strategy with a low modelling uncertainty. A solution strategy comprises

A non-dispersive infrared analyser for analysis of HF in the PPM range

International Nuclear Information System (INIS)

Kartha, V.B.; Patel, N.D.; Venkateswaran, S.

1985-01-01

The determination of trace amounts of HF is of importance in many industrial processes, and in nuclear industry in the production of UF 6 . Mass spectrometric and gas chromatographic methods are difficult to use for this purpose, because of the highly corrosive nature of the samples. Infrared Spectroscopy can be conveniently used with the required sensitivity and it has the added advantage that continuous non-destructive on-line monitoring can be conveniently done. A non-dispersive infrared analyser for determination of HF in UF 6 in the concentration range of 50-2000 ppm has been fabricated and tested. The instrument has been shown to possess high sensitivity and good long term stability, so that it can be used as on-line monitor for non-destructive, continuous analysis. (author)

Comparative Evaluation of the Effect of Menstruation, Pregnancy and Menopause on Salivary Flow Rate, pH and Gustatory Function

Science.gov (United States)

Shetty, Vishwaprakash; Dave, Aparna; Arora, Manpreet; Hans, Vibha; Madan, Ajay

2014-01-01

Objective: There are five situations in a women’s life during which hormone fluctuations make them more susceptible to oral health problems – during puberty, at certain points in the monthly menstrual cycle, when using birth control pills, during pregnancy, and at menopause. The present study aimed at evaluating the effect of menstruation, pregnancy and menopause on salivary flow rate, pH and gustatory function. Materials and Methods: The study was carried out on 120 patients including 30 controls (with normal menstrual cycle of 28 to 30 d) and 90 cases (30 patients within three days of menstruation, 30 pregnant and 30 postmenopausal). Paraffin-stimulated saliva samples were obtained by expectoration to calculate salivary flow rate, pH was measured electrometically and patients were prospectively evaluated for gustatory function. Then, whole mouth taste test was performed in which the quality identification and intensity ratings of taste solutions were measured. Results: No statistically significant difference was found between the groups with respect to salivary flow rate but pH values were significantly lower in post menopausal women (pwomen than intensity of taste perception for other tastes (pwomen reported change in their dietary habits as all of them expressed liking for sweeter food. Conclusion: Reduced salivary flow rate and pH in postmen­opausal women may make them more prone to the occurrence of oral health problems. Also, pregnant and postmenopausal women appeared to have a reduced perception of sucrose, which can alter eating habits, such as intake of more sweet foods whereas no significant difference is observed in taste perception of NaCl, citric acid and quinine hydrochloride between the subjects. PMID:25478455

Acute Kidney Injury due to Menstruation-related Disseminated Intravascular Coagulation in an Adenomyosis Patient: A Case Report

Science.gov (United States)

Son, Jungmin; Seong, Eun Young; Song, Sang Heon; Lee, Soo Bong; Kang, Jin; Yang, Byeong Yun; Lee, Su Jin; Choi, Jong-Ryeol; Lee, Kyu-Sup; Kwak, Ihm Soo

2010-01-01

The authors report a case of acute kidney injury (AKI) resulting from menstruation-related disseminated intravascular coagulation (DIC) in an adenomyosis patient. A 40-yr-old woman who had received gonadotropin for ovulation induction therapy presented with anuria and an elevated serum creatinine level. Her medical history showed primary infertility with diffuse adenomyosis. On admission, her pregnancy test was negative and her menstrual cycle had started 1 day previously. Laboratory data were consistent with DIC, and it was believed to be related to myometrial injury resulting from heavy intramyometrial menstrual flow. Gonadotropin is considered to play an important role in the development of fulminant DIC. This rare case suggests that physicians should be aware that gonadotropin may provoke fulminant DIC in women with adenomyosis. PMID:20808684

I've Never Had My Period, So What Is This Discharge?

Science.gov (United States)

... gray, or green), it's a sign of a vaginal infection. If that happens, see a doctor. Sometimes a ... Vaginal Discharge: What's Normal, What's Not Gyn Checkups Vaginal Yeast Infections All About Menstruation Everything You Wanted to Know ...

Perbedaan Kadar Prostaglandin F2α Cairan Darah Haid (Menstrual Fluid) Pada Dismenore Primer, Sekunder Dan Non Dismenore

OpenAIRE

Prahatama, Apriza

2016-01-01

Introduction: Prevalence of dysmenorrhea, pain at lower abdomen during menstruation, is increasing in reproductive women. Prostaglandin plays an important role in pain stimuli, but no its level is unknown each classification dysmenorrhea. Objective: To determine differences of prostaglandin F2α levels between primary, secondary and non dysmenorrhea. Methods: This study is a comparative analytical study with cross sectional design conducted in H. Adam Malik Hospital from November 2015 to...

Higher pressure periodic CO/sub 2/ laser with non-self-sustaining discharge and UV ionization

Energy Technology Data Exchange (ETDEWEB)

Muratov, E A; Pismennyi, V D; Rakhimov, A T

1979-02-01

Stimulated emission was achieved in a CO/sub 2/ laser operating at 250 torr excited by a periodic non-self-sustaining discharge controlled by a spark source of UV radiation. Use of a UV source operating in periodic pulse regime is shown to permit quasicontinuous operation of the laser with characteristic radiating times up to several hundred microseconds.

Non-Statistical Methods of Analysing of Bankruptcy Risk

Directory of Open Access Journals (Sweden)

Pisula Tomasz

2015-06-01

Full Text Available The article focuses on assessing the effectiveness of a non-statistical approach to bankruptcy modelling in enterprises operating in the logistics sector. In order to describe the issue more comprehensively, the aforementioned prediction of the possible negative results of business operations was carried out for companies functioning in the Polish region of Podkarpacie, and in Slovakia. The bankruptcy predictors selected for the assessment of companies operating in the logistics sector included 28 financial indicators characterizing these enterprises in terms of their financial standing and management effectiveness. The purpose of the study was to identify factors (models describing the bankruptcy risk in enterprises in the context of their forecasting effectiveness in a one-year and two-year time horizon. In order to assess their practical applicability the models were carefully analysed and validated. The usefulness of the models was assessed in terms of their classification properties, and the capacity to accurately identify enterprises at risk of bankruptcy and healthy companies as well as proper calibration of the models to the data from training sample sets.

On the stability, the periodic solutions and the resolution of certain types of non linear equations, and of non linearly coupled systems of these equations, appearing in betatronic oscillations

International Nuclear Information System (INIS)

Valat, J.

1960-12-01

Universal stability diagrams have been calculated and experimentally checked for Hill-Meissner type equations with square-wave coefficients. The study of these equations in the phase-plane has then made it possible to extend the periodic solution calculations to the case of non-linear differential equations with periodic square-wave coefficients. This theory has been checked experimentally. For non-linear coupled systems with constant coefficients, a search was first made for solutions giving an algebraic motion. The elliptical and Fuchs's functions solve such motions. The study of non-algebraic motions is more delicate, apart from the study of nonlinear Lissajous's motions. A functional analysis shows that it is possible however in certain cases to decouple the system and to find general solutions. For non-linear coupled systems with periodic square-wave coefficients it is then possible to calculate the conditions leading to periodic solutions, if the two non-linear associated systems with constant coefficients fall into one of the categories of the above paragraph. (author) [fr

Non-invasive PGAA, PIXE and ToF-ND analyses on Hungarian Bronze Age defensive armour

International Nuclear Information System (INIS)

Marianne Moedlinger; Imre Kovacs; Zoltan Szoekefalvi-Nagy; Ziad El Morr

2014-01-01

Non-invasive, archaeometric analyses on selected Hungarian Bronze Age defensive armour is presented here: three greaves, three helmets two shields as well as one vessel fragment were analysed with PIXE, PGAA and TOF-ND. The detected alloy elemental and phase composition as well as its intergranular or spatial concentration distribution reveals important insights into the alloys used and the manufacturing techniques applied c. 1200-950 BC, and allows to reconstruct the production techniques used during the Late Bronze Age. (author)

Impact of quadratic non-linearity on the dynamics of periodic solutions of a wave equation

International Nuclear Information System (INIS)

Kolesov, Andrei Yu; Rozov, Nikolai Kh

2002-01-01

For the non-linear telegraph equation with homogeneous Dirichlet or Neumann conditions at the end-points of a finite interval the question of the existence and the stability of time-periodic solutions bifurcating from the zero equilibrium state is considered. The dynamics of these solutions under a change of the diffusion coefficient (that is, the coefficient of the second derivative with respect to the space variable) is investigated. For the Dirichlet boundary conditions it is shown that this dynamics substantially depends on the presence - or the absence - of quadratic terms in the non-linearity. More precisely, it is shown that a quadratic non-linearity results in the occurrence, under an unbounded decrease of diffusion, of an infinite sequence of bifurcations of each periodic solution. En route, the related issue of the limits of applicability of Yu.S. Kolesov's method of quasinormal forms to the construction of self-oscillations in singularly perturbed hyperbolic boundary value problems is studied

Menstrual cycle disorders in female volleyball players.

Science.gov (United States)

Wodarska, M; Witkoś, J; Drosdzol-Cop, A; Dąbrowska, J; Dąbrowska-Galas, M; Hartman, M; Plinta, R; Skrzypulec-Plinta, V

2013-07-01

The aim of this study was to examine the relation between increased physical activity and menstrual disorders in adolescent female volleyball players. The study was conducted on 210 Polish female volleyball players, aged 13-17 years, the authorship questionnaire was used. The results of the study showed that irregular menstruation occurred in 19% of girls, spotting between menstrual periods in 27% and heavy menstruation was reported in 33% of girls. Out of all volleyball female players participating in the study, 94 girls (45%) declared absence of menstrual periods after regular cycles. Statistical analysis showed that the more training hours per week, the bigger probability of the occurrence of irregular menstruation. It was concluded that the number of hours of volleyball training per week affects regularity of menstrual cycles in female volleyball players. The absence of menstruation might be caused by the duration of training per week or years of training.

[Experimental testing of Pflüger's reflex hypothesis of menstruation in late 19th century].

Science.gov (United States)

Simmer, H H

1980-07-01

Pflüger's hypothesis of a nerve reflex as the cause of menstruation published in 1865 and accepted by many, nonetheless did not lead to experimental investigations for 25 years. According to this hypothesis the nerve reflex starts in the ovary by an increase of the intraovarian pressure by the growing follicles. In 1884 Adolph Kehrer proposed a program to test the nerve reflex, but only in 1890, Cohnstein artificially increased the intraovarian pressure in women by bimanual compression from the outside and the vagina. His results were not convincing. Six years later, Strassmann injected fluids into ovaries of animals and obtained changes in the uterus resembling those of oestrus. His results seemed to verify a prognosis derived from Pflüger's hypothesis. Thus, after a long interval, that hypothesis had become a paradigma. Though reasons can be given for the delay, it is little understood, why experimental testing started so late.

Analyses of non-fatal accidents in an opencast mine by logistic regression model - a case study.

Science.gov (United States)

Onder, Seyhan; Mutlu, Mert

2017-09-01

Accidents cause major damage for both workers and enterprises in the mining industry. To reduce the number of occupational accidents, these incidents should be properly registered and carefully analysed. This study efficiently examines the Aegean Lignite Enterprise (ELI) of Turkish Coal Enterprises (TKI) in Soma between 2006 and 2011, and opencast coal mine occupational accident records were used for statistical analyses. A total of 231 occupational accidents were analysed for this study. The accident records were categorized into seven groups: area, reason, occupation, part of body, age, shift hour and lost days. The SPSS package program was used in this study for logistic regression analyses, which predicted the probability of accidents resulting in greater or less than 3 lost workdays for non-fatal injuries. Social facilities-area of surface installations, workshops and opencast mining areas are the areas with the highest probability for accidents with greater than 3 lost workdays for non-fatal injuries, while the reasons with the highest probability for these types of accidents are transporting and manual handling. Additionally, the model was tested for such reported accidents that occurred in 2012 for the ELI in Soma and estimated the probability of exposure to accidents with lost workdays correctly by 70%.

On the stability, the periodic solutions and the resolution of certain types of non linear equations, and of non linearly coupled systems of these equations, appearing in betatronic oscillations; Sur la stabilite, les solutions periodiques et la resolution de certaines categories d'equations et systemes d'equations differentielles couplees non lineaires apparaissant dans les oscillations betatroniques

Energy Technology Data Exchange (ETDEWEB)

Valat, J [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

1960-12-15

Universal stability diagrams have been calculated and experimentally checked for Hill-Meissner type equations with square-wave coefficients. The study of these equations in the phase-plane has then made it possible to extend the periodic solution calculations to the case of non-linear differential equations with periodic square-wave coefficients. This theory has been checked experimentally. For non-linear coupled systems with constant coefficients, a search was first made for solutions giving an algebraic motion. The elliptical and Fuchs's functions solve such motions. The study of non-algebraic motions is more delicate, apart from the study of nonlinear Lissajous's motions. A functional analysis shows that it is possible however in certain cases to decouple the system and to find general solutions. For non-linear coupled systems with periodic square-wave coefficients it is then possible to calculate the conditions leading to periodic solutions, if the two non-linear associated systems with constant coefficients fall into one of the categories of the above paragraph. (author) [French] Pour les equations du genre de Hill-Meissner a coefficients creneles, on a calcule des diagrammes universels de stabilite et ceux-ci ont ete verifies experimentalement. L'etude de ces equations dans le plan de phase a permis ensuite d'etendre le calcul des solutions periodiques au cas des equations differentielles non lineaires a coefficients periodiques creneles. Cette theorie a ete verifiee experimentalement. Pour Jes systemes couples non lineaires a coefficients constants, on a d'abord cherche les solutions menant a des mouvements algebriques. Les fonctions elliptiques et fuchsiennes uniformisent de tels mouvements. L'etude de mouvements non algebriques est plus delicate, a part l'etude des mouvements de Lissajous non lineaires. Une analyse fonctionnelle montre qu'il est toutefois possible dans certains cas de decoupler le systeme et de trouver des solutions generales. Pour les

Instrumentation to Monitor Transient Periodic Developing Flow in Non-Newtonian Slurries

Energy Technology Data Exchange (ETDEWEB)

Bamberger, Judith A.; Enderlin, Carl W.

2013-11-15

Staff at Pacific Northwest National Laboratory have conducted mixing and mobilization experiments with non-Newtonian slurries that exhibit Bingham plastic and shear thinning behavior and shear strength. This paper describes measurement techniques applied to identify the interface between flowing and stationary regions of non-Newtonian slurries that are subjected to transient, periodic, developing flows. Techniques were developed to identify the boundary between the flowing and stationary regions, time to mix, characteristic velocities of the flow field produced by the symmetrically spaced nozzles, and the velocity of the upwell formed in the center of the tank by the intersection of flow from four symmetrically spaced nozzles that impinge upon the tank floor. Descriptions of the instruments and instrument performance are presented. These techniques were an effective approach to characterize mixing phenomena, determine mixing energy required to fully mobilize vessel contents and to determine mixing times for process evaluation.

Non-LTE spectral analyses of the lately discovered DB-gap white dwarfs from the SDSS

International Nuclear Information System (INIS)

Huegelmeyer, S D; Dreizler, S

2009-01-01

For a long time, no hydrogen-deficient white dwarfs have been known that have effective temperature between 30 kK and eff < 45 kK (Eisenstein et al. 2006). It has been shown for DO white dwarfs that the relaxation of LTE is necessary to account for non local effects in the atmosphere caused by the intense radiation field. Therefore, we calculated a non-LTE model grid and re-analysed the aforementioned set of SDSS spectra. Our results confirm the existence of DB-gap white dwarfs.

Usefulness of non-linear input-output models for economic impact analyses in tourism and recreation

NARCIS (Netherlands)

Klijs, J.; Peerlings, J.H.M.; Heijman, W.J.M.

2015-01-01

In tourism and recreation management it is still common practice to apply traditional input–output (IO) economic impact models, despite their well-known limitations. In this study the authors analyse the usefulness of applying a non-linear input–output (NLIO) model, in which price-induced input

Measuring modulated luminescence using non-modulated stimulation: Ramping the sample period

DEFF Research Database (Denmark)

Poolton, N.R.J.; Bøtter-Jensen, L.; Andersen, C.E.

2003-01-01

. Directly analogous results to LM-OSL can, however, be achieved with non-modulated excitation sources, by ramping the sample period (RSP) of luminescence detection. RSP-OSL has the distinct advantage over LM-OSL in that, since the excitation remains at full power, data accumulation times (that can...... be considerable) can be reduced by typically 50%. RSP methods are universally applicable and can be employed, for example, where the excitation source is constant heat, rather than light: here, iso-thermal decay of phosphorescence becomes recorded as a sequence of peaks, corresponding to de-trapping of charge...

LINEAR AND NON-LINEAR ANALYSES OF CABLE-STAYED STEEL FRAME SUBJECTED TO SEISMIC ACTIONS

Directory of Open Access Journals (Sweden)

Marko Đuran

2017-01-01

Full Text Available In this study, linear and non-linear dynamic analyses of a cable-stayed steel frame subjected to seismic actions are performed. The analyzed cable-stayed frame is the main supporting structure of a wide-span sports hall. Since the complex dynamic behavior of cable-stayed structures results in significant geometric nonlinearity, a nonlinear time history analysis is conducted. As a reference, an analysis using the European standard approach, the so-called linear modal response spectrum method, is also performed. The analyses are conducted for different seismic actions considering dependence on the response spectrums for various ground types and the corresponding artificially generated accelerograms. Despite fundamental differences between the two analyses, results indicate that the modal response spectrum analysis is surprisingly consistent with the internal forces and bending moment distributions of the nonlinear time history analysis. However, significantly smaller values of bending moments, internal forces, and displacements are obtained with the response spectrum analysis.

[Meta-analyses on measurement precision of non-invasive hemodynamic monitoring technologies in adults].

Science.gov (United States)

Pestel, G; Fukui, K; Higashi, M; Schmidtmann, I; Werner, C

2018-06-01

An ideal non-invasive monitoring system should provide accurate and reproducible measurements of clinically relevant variables that enables clinicians to guide therapy accordingly. The monitor should be rapid, easy to use, readily available at the bedside, operator-independent, cost-effective and should have a minimal risk and side effect profile for patients. An example is the introduction of pulse oximetry, which has become established for non-invasive monitoring of oxygenation worldwide. A corresponding non-invasive monitoring of hemodynamics and perfusion could optimize the anesthesiological treatment to the needs in individual cases. In recent years several non-invasive technologies to monitor hemodynamics in the perioperative setting have been introduced: suprasternal Doppler ultrasound, modified windkessel function, pulse wave transit time, radial artery tonometry, thoracic bioimpedance, endotracheal bioimpedance, bioreactance, and partial CO 2 rebreathing have been tested for monitoring cardiac output or stroke volume. The photoelectric finger blood volume clamp technique and respiratory variation of the plethysmography curve have been assessed for monitoring fluid responsiveness. In this manuscript meta-analyses of non-invasive monitoring technologies were performed when non-invasive monitoring technology and reference technology were comparable. The primary evaluation criterion for all studies screened was a Bland-Altman analysis. Experimental and pediatric studies were excluded, as were all studies without a non-invasive monitoring technique or studies without evaluation of cardiac output/stroke volume or fluid responsiveness. Most studies found an acceptable bias with wide limits of agreement. Thus, most non-invasive hemodynamic monitoring technologies cannot be considered to be equivalent to the respective reference method. Studies testing the impact of non-invasive hemodynamic monitoring technologies as a trend evaluation on outcome, as well as

Characteristics of non-response in the Danish Health Interview Surveys, 1987-1994

DEFF Research Database (Denmark)

Kjøller, Mette; Thoning, Henrik

2005-01-01

BACKGROUND: The types and quantity of non-response in surveys influence the extent to which the results may be generalized. This study analysed trends in non-response in the Danish Health Interview Surveys from 1987 to 1994 and used the National Patient Registry to assess whether non-response bia......BACKGROUND: The types and quantity of non-response in surveys influence the extent to which the results may be generalized. This study analysed trends in non-response in the Danish Health Interview Surveys from 1987 to 1994 and used the National Patient Registry to assess whether non...... respondents before data collection but similar during and after data collection. The rate was higher during the whole period among ill or disabled non-respondents. Among people who could not be contacted during the data collection period a higher admission rate was only found immediately before and during...

Pubertal status, interaction with significant others, and self-esteem of adolescent girls.

Science.gov (United States)

Lacković-Grgin, K; Dekovíc, M; Opacić, G

1994-01-01

The aim of this study was to examine the relationship between pubertal status, the quality of interactions with significant others, and the self-esteem of adolescent girls. The model which was tested, hypothesized that pubertal status affects self-esteem through girls' interactions with their parents and friends. Pubertal status was operationalized as the number of months between occurrence of the first menstrual periods and time of the investigation. The measure of self-esteem was the shortened form of the Coopersmith Self-Esteem Inventory. Analyses revealed that girls who begun menstruating six months before the investigation obtained higher scores on the measure of self-esteem than did girls who had been menstruating 13 months or more. The best predictor of self-esteem, however, was the quality of interaction with their mothers. The results support the theoretical view that stresses the importance of interaction with significant others for the development of self-esteem.

An Early Window of Opportunity for Promoting Girls' Health: Policy Implications of the Girl's Puberty Book Project in Tanzania

Science.gov (United States)

Sommer, Marni

2011-01-01

The onset of puberty, and specifically menstruation, is an opportune moment for reaching girls as they transition into adolescence and young womanhood. Despite the importance of this transitional period, the reproductive health community has tended to overlook the onset of menstruation and early puberty in global, national and local policy and…

Growth Modeling with Non-Ignorable Dropout: Alternative Analyses of the STAR*D Antidepressant Trial

Science.gov (United States)

Muthén, Bengt; Asparouhov, Tihomir; Hunter, Aimee; Leuchter, Andrew

2011-01-01

This paper uses a general latent variable framework to study a series of models for non-ignorable missingness due to dropout. Non-ignorable missing data modeling acknowledges that missingness may depend on not only covariates and observed outcomes at previous time points as with the standard missing at random (MAR) assumption, but also on latent variables such as values that would have been observed (missing outcomes), developmental trends (growth factors), and qualitatively different types of development (latent trajectory classes). These alternative predictors of missing data can be explored in a general latent variable framework using the Mplus program. A flexible new model uses an extended pattern-mixture approach where missingness is a function of latent dropout classes in combination with growth mixture modeling using latent trajectory classes. A new selection model allows not only an influence of the outcomes on missingness, but allows this influence to vary across latent trajectory classes. Recommendations are given for choosing models. The missing data models are applied to longitudinal data from STAR*D, the largest antidepressant clinical trial in the U.S. to date. Despite the importance of this trial, STAR*D growth model analyses using non-ignorable missing data techniques have not been explored until now. The STAR*D data are shown to feature distinct trajectory classes, including a low class corresponding to substantial improvement in depression, a minority class with a U-shaped curve corresponding to transient improvement, and a high class corresponding to no improvement. The analyses provide a new way to assess drug efficiency in the presence of dropout. PMID:21381817

Improved harmonic balance approach to periodic solutions of non-linear jerk equations

International Nuclear Information System (INIS)

Wu, B.S.; Lim, C.W.; Sun, W.P.

2006-01-01

An analytical approximate approach for determining periodic solutions of non-linear jerk equations involving third-order time-derivative is presented. This approach incorporates salient features of both Newton's method and the method of harmonic balance. By appropriately imposing the method of harmonic balance to the linearized equation, the approach requires only one or two iterations to predict very accurate analytical approximate solutions for a large range of initial velocity amplitude. One typical example is used to verify and illustrate the usefulness and effectiveness of the proposed approach

Interpretation of Actinide-Distribution Data Obtained from Non-Destructive and Destructive Post-Test Analyses of an Intact-Core Column of Culebra Dolomite

International Nuclear Information System (INIS)

LUCERO, DANIEL A.; PERKINS, W. GEORGE

1999-01-01

The US DOE, with technical assistance from Sandia National Laboratories, has successfully received EPA certification and opened the Waste Isolation Pilot Plant (WIPP), a nuclear waste disposal facility located approximately 42 km east of Carlsbad, New Mexico. Performance assessment analyses indicate that human intrusions by inadvertent, intermittent drilling for resources provide the only credible mechanisms for releases of radionuclides from the disposal system. In modeling long-term brine releases, subsequent to a drilling event, potential migration pathways through the permeable layers of rock above the Salado formation were analyzed. Major emphasis is placed on the Culebra Member of the Rustler Formation because this is the most transmissive geologic layer overlying the WIPP site. In order to help quantify parameters for the calculated releases, radionuclide transport experiments have been earned out using intact-core columns obtained from the Culebra dolomite member of the Rustler Formation within the WIPP site. This paper deals primarily with results of analyses for 241 Pu and 241 Am distributions developed during transport experiments in one of these cores. Transport experiments were done using a synthetic brine that simulates Culebra brine at the core recovery location (the WIPP air-intake shaft--AIS). Hydraulic characteristics (i.e., apparent porosity and apparent dispersion coefficient) for intact-core columns were obtained via experiments using the conservative tracer 22 Na. Elution experiments carried out over periods of a few days with tracers 232 U and 239 Np indicated that these tracers were weakly retarded as indicated by delayed elution of the species. Elution experiments with tracers 241 Pu and 241 Am were attempted, but no elution of either species has been observed to date, including experiments of many months' duration. In order to quantify retardation of the non-eluted species 241 Pu and 241 Am after a period of brine flow, non-destructive and

Testing periodically integrated autoregressive models

NARCIS (Netherlands)

Ph.H.B.F. Franses (Philip Hans); M.J. McAleer (Michael)

1997-01-01

textabstractPeriodically integrated time series require a periodic differencing filter to remove the stochastic trend. A non-periodic integrated time series needs the first-difference filter for similar reasons. When the changing seasonal fluctuations for the non-periodic integrated series can be

The Simulation and Experiment of a Non-Cross-Feeding Printed Log-Periodic Antenna

Directory of Open Access Journals (Sweden)

Chun-Ying Kang

2015-01-01

Full Text Available A non-cross-fed printed log-periodic antenna is simulated and studied experimentally. To avoid complex feeding with long coaxial line, the non-cross-feeding structure is applied in this antenna. The software CST Microwave Studio is employed to simulate the proposed antenna, and the optimized antenna model is obtained. According to the simulation results, the antenna prototype is produced and measured. Simulation and measured results show that the antenna is with S11<-10 dB in band of 4.2–9.2 GHz. And the radiation pattern and gain vary steadily in this band, which achieves requirements for wideband antenna. This antenna design can be extended to the design of the antenna integrated in communication circuit.

Periodic feedback stabilization for linear periodic evolution equations

CERN Document Server

Wang, Gengsheng

2016-01-01

This book introduces a number of recent advances regarding periodic feedback stabilization for linear and time periodic evolution equations. First, it presents selected connections between linear quadratic optimal control theory and feedback stabilization theory for linear periodic evolution equations. Secondly, it identifies several criteria for the periodic feedback stabilization from the perspective of geometry, algebra and analyses respectively. Next, it describes several ways to design periodic feedback laws. Lastly, the book introduces readers to key methods for designing the control machines. Given its coverage and scope, it offers a helpful guide for graduate students and researchers in the areas of control theory and applied mathematics.

A CROSS - SECTIONAL STUDY OF KNOWLEDGE, ATTITUDE AND PRACTICES REGARDING MENSTRUAL PATTERN IN ADOLESCENT GIRL

Directory of Open Access Journals (Sweden)

Preeti

2015-06-01

Full Text Available Adolescence is a transitional period during which a child matures into an adult. Menstrual related problem contribute to school absenteeism. beliefs, concepts, hygiene , and knowledge attitude about menstruation is objectively analysed and found that menarche was attained by 70% girls at 12 - 13 years and the mother helped the girls with information , 76% used the old clothes and reused them . 10% of the girls had school absenteeism. There is a need for imparting knowledge by including in the school curriculum.

Modal Analysis in Periodic, Time-Varying Systems with emphasis to the Coupling between Flexible Rotating Beams and Non-Rotating Flexible Structures

DEFF Research Database (Denmark)

Saracho, C. M.; Santos, Ilmar

2003-01-01

The analysis of dynamical response of a system built by a non-rotating structure coupled to flexible rotating beams is the purpose of this work. The effect of rotational speed upon the beam natural frequencies is well-known, so that an increase in the angular speeds leads to an increase in beam...... natural frequencies, the so-called centrifugal stiffening. The equations of motion of such a global system present matrices with time-depending coefficients, which vary periodically with the angular rotor speed, and introduce parametric vibrations into the system response. The principles of modal analysis...... for time-invariant linear systems are expanded to investigate time-varying systems. Concepts as eigenvalues and eigenvectors, which in this special case are also time-varying, are used to analyse the dynamical response of global system. The time-varying frequencies and modes are also illustrated....

Non Linear Analyses for the Evaluation of Seismic Behavior of Mixed R.C.-Masonry Structures

International Nuclear Information System (INIS)

Liberatore, Laura; Tocci, Cesare; Masiani, Renato

2008-01-01

In this work the seismic behavior of masonry buildings with mixed structural system, consisting of perimeter masonry walls and internal r.c. frames, is studied by means of non linear static (pushover) analyses. Several aspects, like the distribution of seismic action between masonry and r.c. elements, the local and global behavior of the structure, the crisis of the connections and the attainment of the ultimate strength of the whole structure are examined. The influence of some parameters, such as the masonry compressive and tensile strength, on the structural behavior is investigated. The numerical analyses are also repeated on a building in which the r.c. internal frames are replaced with masonry walls

Galectin-7 is important for normal uterine repair following menstruation.

Science.gov (United States)

Evans, Jemma; Yap, Joanne; Gamage, Thillini; Salamonsen, Lois; Dimitriadis, Evdokia; Menkhorst, Ellen

2014-08-01

Menstruation involves the shedding of the functional layer of the endometrium in the absence of pregnancy. At sites where tissue shedding is complete, re-epithelialization of the tissue is essential for repair and termination of bleeding. The complement of growth factors that mediate post-menstrual endometrial repair are yet to be completely elucidated. Galectins regulate many cell functions important for post-menstrual repair, such as cell adhesion and migration. Galectin-7 has a well characterized role in re-epithelialization and wound healing. We hypothesized that galectin-7 would be important in re-epithelialization during post-menstrual repair. We aimed to identify endometrial expression of galectin-7 in women undergoing normal endometrial repair and in women with amenorrhoea who do not experience endometrial breakdown and repair, and to determine whether galectin-7 enhances endometrial re-epithelialization in vitro. Galectin-7 immunolocalized to the endometrial luminal and glandular epithelium during the late secretory and menstrual phases, and to decidualized stroma in regions exhibiting tissue breakdown. Immunostaining intensity was significantly reduced in the endometrium of women with amenorrhoea compared with normally cycling woman. ELISA identified galectin-7 in menstrual fluid at significantly elevated levels compared with matched peripheral plasma. Exogenous galectin-7 (2.5 µg/ml) significantly enhanced endometrial epithelial wound repair in vitro; this was abrogated by inhibition of integrin binding. Galectin-7 elevated epithelial expression of extracellular matrix-related molecules likely involved in repair including β-catenin, contactin and TGF-β1. In conclusion, galectin-7 is produced by the premenstrual and menstrual endometrium, where it accumulates in menstrual fluid and likely acts as a paracrine factor to facilitate post-menstrual endometrial re-epithelialization. © The Author 2014. Published by Oxford University Press on behalf of the

A Three-period Samuelson-Diamond Growth Model

DEFF Research Database (Denmark)

Blomgren-Hansen, Niels

2005-01-01

Samuelson (1958) analyses a three-period model, whereas Diamod (1965) considers a two-period model. This difference poses the question whether the insights derived by analysing the simple two-period model carry over in the more complicated three-period case. They do. The Samuelson model (no produ...

Drought periods in non-mountainous part of South Bulgaria on the background of climate change

Directory of Open Access Journals (Sweden)

Nikolova Nina

2012-01-01

Full Text Available The scientific investigations and various analyses show a trend towards a significant extension of water scarcity across Europe. Decreasing of precipitation totals and increasing of drought periods are characteristic for many regions of Bulgaria. Often high temperatures, strong winds and low relative humidity occur in conjunction with the drought. This makes the drought very strong expressed. The present work aims to analyze drought periods in South Bulgaria in terms of its temporal variability, intensity, seasonal and territorial differences. The study areas are one of the main agricultural areas in Bulgaria and because of this investigation of drought in this region is very important. Drought periods are investigated on the base of seasonal precipitation totals and precipitation indices. The data for monthly precipitation from nine meteorological stations situated at the regions with different geographical conditions are used. The deviations of the seasonal and annual precipitation from normal (precipitation for the period 1961-1990 are used to determine drought periods in investigated stations. The duration of drought event is determined by Cumulative Precipitation Anomalies (CA. The Standardized Precipitation Indices (SPI are calculated in order to determine moisture conditions and occurrence of drought periods in the investigated stations. The results from the research show that drought was widespread in 1945 and 1949. The years with dry seasons are more often during 80’s and 90’s but drought during these periods was observed in a few of the investigated stations.

Numerical insight into the seismic behavior of eight masonry towers in Northern Italy: FE pushover vs non-linear dynamic analyses

International Nuclear Information System (INIS)

Milani, Gabriele; Valente, Marco

2015-01-01

This study presents some FE results regarding the behavior under horizontal loads of eight existing masonry towers located in the North-East of Italy. The towers, albeit unique for geometric and architectural features, show some affinities which justify a comparative analysis, as for instance the location and the similar masonry material. Their structural behavior under horizontal loads is therefore influenced by geometrical issues, such as slenderness, walls thickness, perforations, irregularities, presence of internal vaults, etc., all features which may be responsible for a peculiar output. The geometry of the towers is deduced from both existing available documentation and in-situ surveys. On the basis of such geometrical data, a detailed 3D realistic mesh is conceived, with a point by point characterization of each single geometric element. The FE models are analysed under seismic loads acting along geometric axes of the plan section, both under non-linear static (pushover) and non-linear dynamic excitation assumptions. A damage-plasticity material model exhibiting softening in both tension and compression, already available in the commercial code Abaqus, is used for masonry. Pushover analyses are performed with both G1 and G2 horizontal loads distribution, according to Italian code requirements, along X+/− and Y+/− directions. Non-linear dynamic analyses are performed along both X and Y directions with a real accelerogram scaled to different peak ground accelerations. Some few results are presented in this paper. It is found that the results obtained with pushover analyses reasonably well fit expensive non-linear dynamic simulations, with a slightly less conservative trend

Numerical insight into the seismic behavior of eight masonry towers in Northern Italy: FE pushover vs non-linear dynamic analyses

Energy Technology Data Exchange (ETDEWEB)

Milani, Gabriele, E-mail: milani@stru.polimi.it, E-mail: gabriele.milani@polimi.it; Valente, Marco [Department of Architecture, Built Environment and Construction Engineering (ABC), Politecnico di Milano, Piazza Leonardo da Vinci 32, 20133 Milan (Italy)

2015-12-31

This study presents some FE results regarding the behavior under horizontal loads of eight existing masonry towers located in the North-East of Italy. The towers, albeit unique for geometric and architectural features, show some affinities which justify a comparative analysis, as for instance the location and the similar masonry material. Their structural behavior under horizontal loads is therefore influenced by geometrical issues, such as slenderness, walls thickness, perforations, irregularities, presence of internal vaults, etc., all features which may be responsible for a peculiar output. The geometry of the towers is deduced from both existing available documentation and in-situ surveys. On the basis of such geometrical data, a detailed 3D realistic mesh is conceived, with a point by point characterization of each single geometric element. The FE models are analysed under seismic loads acting along geometric axes of the plan section, both under non-linear static (pushover) and non-linear dynamic excitation assumptions. A damage-plasticity material model exhibiting softening in both tension and compression, already available in the commercial code Abaqus, is used for masonry. Pushover analyses are performed with both G1 and G2 horizontal loads distribution, according to Italian code requirements, along X+/− and Y+/− directions. Non-linear dynamic analyses are performed along both X and Y directions with a real accelerogram scaled to different peak ground accelerations. Some few results are presented in this paper. It is found that the results obtained with pushover analyses reasonably well fit expensive non-linear dynamic simulations, with a slightly less conservative trend.

Analyses of Environmental Impacts of Non Hazardous Regional Landfills in Macedonia

Directory of Open Access Journals (Sweden)

Katerina Donevska

2013-12-01

Full Text Available This paper presents an assessment of potential environmental impacts for eight planned non-hazardous regional landfills in Macedonia. Waste quantities for each waste management region and landfill capacities are estimated. Expected leachate quantities are calculated using Water Balance Method. Analyses and comparison of the likely landfill leachate per capita are presented, demonstrating that higher rates of leachate are generated per capita in waste management regions with higher annual sums of rainfall. An assessment of the potential landfill impacts on the water environment taking into consideration local geology and hydrogeology conditions is presented. Some general measures for leachate treatment that are in compliance with the modern EU standards are indicated. The goal of the study is to facilitate a better understanding about the sustainable waste management practices in cases of landfilling of municipal solid waste.

Comparative analysis between endometrial proteomes of pregnant and non-pregnant ewes during the peri-implantation period.

Science.gov (United States)

Zhao, Haichao; Sui, Linlin; Miao, Kai; An, Lei; Wang, Dong; Hou, Zhuocheng; Wang, Rui; Guo, Min; Wang, Zhilong; Xu, Jiqiang; Wu, Zhonghong; Tian, Jianhui

2015-01-01

Early pregnancy failure has a profound impact on both human reproductive health and animal production. 2/3 pregnancy failures occur during the peri-implantation period; however, the underlying mechanism(s) remains unclear. Well-organized modification of the endometrium to a receptive state is critical to establish pregnancy. Aberrant endometrial modification during implantation is thought to be largely responsible for early pregnancy loss. In this study, using well-managed recipient ewes that received embryo transfer as model, we compared the endometrial proteome between pregnant and non-pregnant ewes during implantation period. After embryo transfer, recipients were assigned as pregnant or non-pregnant ewes according to the presence or absence of an elongated conceptus at Day 17 of pregnancy. By comparing the endometrial proteomic profiles between pregnant and non-pregnant ewes, we identified 94 and 257 differentially expressed proteins (DEPs) in the endometrial caruncular and intercaruncular areas, respectively. Functional analysis showed that the DEPs were mainly associated with immune response, nutrient transport and utilization, as well as proteasome-mediated proteolysis. These analysis imply that dysfunction of these biological processes or pathways of DEP in the endometrium is highly associated with early pregnancy loss. In addition, many proteins that are essential for the establishment of pregnancy showed dysregulation in the endometrium of non-pregnant ewes. These proteins, as potential candidates, may contribute to early pregnancy loss.

Three-Dimensional Design of a Non-Axisymmetric Periodic Permanent Magnet Focusing System

CERN Document Server

Chen Chi Ping; Radovinsky, Alexey; Zhou, Jing

2005-01-01

A three-dimensional (3D) design is presented of a non-axisymmetric periodic permanent magnet focusing system which will be used to focus a large-aspect-ratio, ellipse-shaped, space-charge-dominated electron beam. In this design, an analytic theory is used to specify the magnetic profile for beam transport. The OPERA3D code is used to compute and optimize a realizable magnet system. Results of the magnetic design are verified by two-dimensional particle-in-cell and three-dimensional trajectory simulations of beam propagation using PFB2D and OMNITRAK, respectively. Results of fabrication tolerance studies are discussed.

[Mining analysis on composition and medication of menstruation prescriptions in Fu Qingzhu's Obstetrics and Gynecology].

Science.gov (United States)

Zhu, Jia-qing; Che, Yu-xia

2015-04-01

In this paper, menstruation prescriptions were selected from "Fu Qingzhu's Obstetrics and Gynecology" and analyzed by using GRI algorithm, correlation analysis, hierarchical clustering method through SPSS, Clementine and traditional Chinese medicine (TCM) inheritance auxiliary systems, in order to screen out 15 menopathy prescriptions, which involve 45 traditional Chinese medicine herbs. In the study, blood-tonifying and qi-tonifying herbs were found to be frequent in the prescriptions. The most frequent single herb was white paeony root, accounting for 9.6% in the total number of prescriptions; The most frequent herb pairs were white paeony root-radix rehmanniae preparata and paeony root-angelica sinensis. Among Fu Shan's menopathy prescriptions, 61 herbal pairs showed a correlation coefficient exceeding 0.05, which evolved into 16 pairs of core combinations. The analysis showed that menopathy prescriptions in volume 1 of "Fu Qingzhu's Obstetrics and Gynecology" focused on tonic traditional Chinese medicines involving liver, spleen and kidney and were adjusted according to changes in qi, blood, cold, hot and wet, which could provide a specific reference for further studies on Fu Shan's academic thoughts and traditional Chinese medicine clinical treatment of menopathy.

Tsallis non-extensive statistical mechanics in the ionospheric detrended total electron content during quiet and storm periods

Science.gov (United States)

Ogunsua, B. O.; Laoye, J. A.

2018-05-01

In this paper, the Tsallis non-extensive q-statistics in ionospheric dynamics was investigated using the total electron content (TEC) obtained from two Global Positioning System (GPS) receiver stations. This investigation was carried out considering the geomagnetically quiet and storm periods. The micro density variation of the ionospheric total electron content was extracted from the TEC data by method of detrending. The detrended total electron content, which represent the variation in the internal dynamics of the system was further analyzed using for non-extensive statistical mechanics using the q-Gaussian methods. Our results reveals that for all the analyzed data sets the Tsallis Gaussian probability distribution (q-Gaussian) with value q > 1 were obtained. It was observed that there is no distinct difference in pattern between the values of qquiet and qstorm. However the values of q varies with geophysical conditions and possibly with local dynamics for the two stations. Also observed are the asymmetric pattern of the q-Gaussian and a highly significant level of correlation for the q-index values obtained for the storm periods compared to the quiet periods between the two GPS receiver stations where the TEC was measured. The factors responsible for this variation can be mostly attributed to the varying mechanisms resulting in the self-reorganization of the system dynamics during the storm periods. The result shows the existence of long range correlation for both quiet and storm periods for the two stations.

Tailoring of the electrical and thermal properties using ultra-short period non-symmetric superlattices

Directory of Open Access Journals (Sweden)

Paulina Komar

2016-10-01

Full Text Available Thermoelectric modules based on half-Heusler compounds offer a cheap and clean way to create eco-friendly electrical energy from waste heat. Here we study the impact of the period composition on the electrical and thermal properties in non-symmetric superlattices, where the ratio of components varies according to (TiNiSnn:(HfNiSn6−n, and 0 ⩽ n ⩽ 6 unit cells. The thermal conductivity (κ showed a strong dependence on the material content achieving a minimum value for n = 3, whereas the highest value of the figure of merit ZT was achieved for n = 4. The measured κ can be well modeled using non-symmetric strain relaxation applied to the model of the series of thermal resistances.

Long-term analyses of snow dynamics within the french Alps on the 1900-2100 period. Analyses of historical snow water equivalent observations, modelisations and projections of a hundred of snow courses.

Science.gov (United States)

Mathevet, T.; Joel, G.; Gottardi, F.; Nemoz, B.

2017-12-01

The aim of this communication is to present analyses of climate variability and change on snow water equivalent (SWE) observations, reconstructions (1900-2016) and scenarii (2020-2100) of a hundred of snow courses dissiminated within the french Alps. This issue became particularly important since a decade, in regions where snow variability had a large impact on water resources availability, poor snow conditions in ski resorts and artificial snow production. As a water resources manager in french mountainuous regions, EDF (french hydropower company) has developed and managed a hydrometeorological network since 1950. A recent data rescue research allowed to digitize long term SWE manual measurments of a hundred of snow courses within the french Alps. EDF have been operating an automatic SWE sensors network, complementary to the snow course network. Based on numerous SWE observations time-series and snow accumulation and melt model (Garavaglia et al., 2017), continuous daily historical SWE time-series have been reconstructed within the 1950-2016 period. These reconstructions have been extented to 1900 using 20 CR reanalyses (ANATEM method, Kuentz et al., 2015) and up to 2100 using GIEC Climate Change scenarii. Considering various mountainous areas within the french Alps, this communication focuses on : (1) long term (1900-2016) analyses of variability and trend of total precipitation, air temperature, snow water equivalent, snow line altitude, snow season length , (2) long term variability of hydrological regime of snow dominated watersheds and (3) future trends (2020 -2100) using GIEC Climate Change scenarii. Comparing historical period (1950-1984) to recent period (1984-2016), quantitative results within a region in the north Alps (Maurienne) shows an increase of air temperature by 1.2 °C, an increase of snow line height by 200m, a reduction of SWE by 200 mm/year and a reduction of snow season length by 15 days. These analyses will be extended from north to south

Period doubling of azimuthal oscillations on a non-neutral magnetized electron column

International Nuclear Information System (INIS)

Boswell, R.W.

1985-01-01

The low-frequency azimuthal oscillations on a non-neutral magnetized electron column of very low density are investigated. A perturbation analysis of the slow mode of the rigid rotator equilibrium is developed to illustrate the nature of large-amplitude fundamental-mode oscillations. The results of this theoretical analysis show two important characteristics: firstly, as the perturbation amplitude is increased the wave form ceases to be purely sinusoidal and shows period doubling. Secondly, above a certain threshold, all harmonics of the wave grow and the wave breaks. The results of the former are compared with a simple electron beam experiment and are found to be in good qualitative agreement. (author)

Authorship characteristics of orthodontic randomized controlled trials, systematic reviews, and meta-analyses in non-orthodontic journals with impact factor.

Science.gov (United States)

Alqaydi, Ahlam R; Kanavakis, Georgios; Naser-Ud-Din, Shazia; Athanasiou, Athanasios E

2017-12-08

This study was conducted to explore authorship characteristics and publication trends of all orthodontic randomized controlled trials (RCTs), systematic reviews (SRs), and meta-analyses (MAs) published in non-orthodontic journals with impact factor (IF). Appropriate research strategies were developed to search for all articles published until December 2015, without restrictions regarding language or publication status. The initial search generated 4524 results, but after application of the inclusion criteria, the final number of articles was reduced to 274 (SRs: 152; MAs: 36; and RCTs: 86). Various authorship characteristics were recorded for each article. Frequency distributions for all parameters were explored with Pearson chi-square for independence at the 0.05 level of significance. More than half of the included publications were SRs (55.5 per cent), followed by RCTs (31.4 per cent) and MAs (13.1 per cent); one hundred seventy-eight (65 per cent) appeared in dental journals and 96 (35 per cent) were published in non-dental journals. The last decade was significantly more productive than the period before 2006, with 236 (86.1 per cent) articles published between 2006 and 2015. European countries produced 51.5 per cent of the total number of publications, followed by Asia (18.6 per cent) and North America (USA and Canada; 16.8 per cent). Studies published in journals without IF were not included. Level-1 evidence orthodontic literature published in non-orthodontic journals has significantly increased during 2006-15. This indicates a larger interest of other specialty journals in orthodontic related studies and a trend for orthodontic authors to publish their work in journals with impact in broader fields of dentistry and medicine. © The Author(s) 2017. Published by Oxford University Press on behalf of the European Orthodontic Society. All rights reserved. For permissions, please email: journals.permissions@oup.com

In-season training periodization of professional soccer players

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A Los Arcos

2017-04-01

Full Text Available The aim of this study was to quantify the seasonal perceived respiratory and muscular training loads (i.e., sRPEres-TL and sRPEmus-TL completed by elite-oriented young professional soccer players. Twentyfour players (20.3 ± 2.0 years belonging to the same reserve team of a Spanish La Liga club participated in this study. Only the players that were available to train for a whole week with the team and also to play the weekly game were considered: Starters, players that participated in the match for at least 45 min and Non- Starters, players that did not participate or played less than 45 minutes in the match. The competitive period was analysed after the division into 5x6-8 week blocks and 35x1 week microcycles. Data were also analysed with respect to number of days before the immediate match. Weekly TL variation across the in-season blocks was trivial-small for both groups except between Block 2 and Block 3 (ES= moderate. Substantial TL differences (ES= small–very likely were found between training days, the TL pattern being a progressive increase up to MD-3 followed by a decrease until MD-1. Except for the match, sRPEres-/sRPEmus-TL was very similar between Starters and Non-Starters. In summary, perceived TL across the season displayed limited variation. Coaches periodized training contents to attain the highest weekly TL 72 hours before the match to progressively unload the players between MD-3 and the match day. The data revealed that the TL arising from the weekly game was solely responsible for the observed higher weekly TL of Starters in comparison with Non-Starters.

Nonparametric Analyses of Log-Periodic Precursors to Financial Crashes

Science.gov (United States)

Zhou, Wei-Xing; Sornette, Didier

We apply two nonparametric methods to further test the hypothesis that log-periodicity characterizes the detrended price trajectory of large financial indices prior to financial crashes or strong corrections. The term "parametric" refers here to the use of the log-periodic power law formula to fit the data; in contrast, "nonparametric" refers to the use of general tools such as Fourier transform, and in the present case the Hilbert transform and the so-called (H, q)-analysis. The analysis using the (H, q)-derivative is applied to seven time series ending with the October 1987 crash, the October 1997 correction and the April 2000 crash of the Dow Jones Industrial Average (DJIA), the Standard & Poor 500 and Nasdaq indices. The Hilbert transform is applied to two detrended price time series in terms of the ln(tc-t) variable, where tc is the time of the crash. Taking all results together, we find strong evidence for a universal fundamental log-frequency f=1.02±0.05 corresponding to the scaling ratio λ=2.67±0.12. These values are in very good agreement with those obtained in earlier works with different parametric techniques. This note is extracted from a long unpublished report with 58 figures available at , which extensively describes the evidence we have accumulated on these seven time series, in particular by presenting all relevant details so that the reader can judge for himself or herself the validity and robustness of the results.

Non-destructive XRF analyses of fine-grained basalts from Eiao, Marquesas Islands

International Nuclear Information System (INIS)

Charleux, M.; McAlister, A.; Mills, P.R.; Lundblad, S.P.

2014-01-01

The Marquesan island of Eiao was an important source of fine-grained basalt in Central East Polynesia, with examples being identified in archaeological assemblages throughout the region. However, compared to many other large-scale Polynesian basalt sources, little has been published about the physical extent and geochemical variability of tool-quality basalt on Eiao; prior to our study, only a single site with evidence of stone extraction had been identified and geochemical information was limited to less than two dozen samples. In this paper we report geochemical data for 225 additional basalt specimens collected on Eiao. Our analyses were conducted non-destructively using three EDXRF instruments: one lab-based unit and two portable analysers. The majority of our sample, identified here as Group 1, possesses geochemical and physical characteristics similar to those reported in previous studies. Group 1 samples were collected from various locations on Eiao suggesting that, rather than being limited to a single quarry site, fine-grained basalt was extracted from multiple sources throughout the island. In addition, we identified a second group (Group 2), which possesses a distinct geochemistry, a coarser grain and often an unusual reddish colour. Evidence from Eiao indicates that Group 2 stone was regularly utilised and our analysis of an adze collected on Hiva Oa Island suggests that this material was distributed at least as far as the southern Marquesas. (author)

Non-periodic preventive maintenance with reliability thresholds for complex repairable systems

International Nuclear Information System (INIS)

Lin, Zu-Liang; Huang, Yeu-Shiang; Fang, Chih-Chiang

2015-01-01

In general, a non-periodic condition-based PM policy with different condition variables is often more effective than a periodic age-based policy for deteriorating complex repairable systems. In this study, system reliability is estimated and used as the condition variable, and three reliability-based PM models are then developed with consideration of different scenarios which can assist in evaluating the maintenance cost for each scenario. The proposed approach provides the optimal reliability thresholds and PM schedules in advance by which the system availability and quality can be ensured and the organizational resources can be well prepared and managed. The results of the sensitivity anlysis indicate that PM activities performed at a high reliability threshold can not only significantly improve the system availability but also efficiently extend the system lifetime, although such a PM strategy is more costly than that for a low reliabiltiy threshold. The optimal reliability threshold increases along with the number of PM activities to prevent future breakdowns caused by severe deterioration, and thus substantially reduces repair costs. - Highlights: • The PM problems for repairable deteriorating systems are formulated. • The structural properties of the proposed PM models are investigated. • The corresponding algorithms to find the optimal PM strategies are provided. • Imperfect PM activities are allowed to reduce the occurences of breakdowns. • Provide managers with insights about the critical factors in the planning stage

An Unusual Presentation of 46,XY Pure Gonadal Dysgenesis: Spontaneous Breast Development and Menstruation.

Science.gov (United States)

Çatlı, Gönül; Alparslan, Caner; Can, P Şule; Akbay, Sinem; Kelekçi, Sefa; Atik, Tahir; Özyılmaz, Berk; Dündar, Bumin N

2015-06-01

46,XY pure gonadal dysgenesis (Swyer syndrome) is characterized by normal female genitalia at birth. It usually first becomes apparent in adolescence with delayed puberty and amenorrhea. Rarely, patients can present with spontaneous breast development and/or menstruation. A fifteen-year-old girl presented to our clinic with the complaint of primary amenorrhea. On physical examination, her external genitals were completely female. Breast development and pubic hair were compatible with Tanner stage V. Hormonal evaluation revealed a hypergonadotropic state despite a normal estrogen level. Chromosome analysis revealed a 46,XY karyotype. Pelvic ultrasonography showed small gonads and a normal sized uterus for age. SRY gene expression was confirmed by multiplex polymerase chain reaction. Direct sequencing on genomic DNA did not reveal a mutation in the SRY, SF1 and WT1 genes. After the diagnosis of Swyer syndrome was made, the patient started to have spontaneous menstrual cycles and therefore failed to attend her follow-up visits. After nine months, the patient underwent diagnostic laparoscopy. Frozen examination of multiple biopsies from gonad tissues revealed gonadoblastoma. With this report, we emphasize the importance of performing karyotype analysis, which is diagnostic for Swyer syndrome, in all cases with primary or secondary amenorrhea even in the presence of normal breast development. We also suggest that normal pubertal development in patients with Swyer syndrome may be associated with the presence of a hormonally active tumor.

Positron lifetime calculation for the elements of the periodic table.

Science.gov (United States)

Campillo Robles, J M; Ogando, E; Plazaola, F

2007-04-30

Theoretical positron lifetime values have been calculated systematically for most of the elements of the periodic table. Self-consistent and non-self-consistent schemes have been used for the calculation of the electronic structure in the solid, as well as different parametrizations for the positron enhancement factor and correlation energy. The results obtained have been studied and compared with experimental data, confirming the theoretical trends. As is known, positron lifetimes in bulk show a periodic behaviour with atomic number. These calculations also confirm that monovacancy lifetimes follow the same behaviour. The effects of enhancement factors used in calculations have been commented upon. Finally, we have analysed the effects that f and d electrons have on positron lifetimes.

Positron lifetime calculation for the elements of the periodic table

International Nuclear Information System (INIS)

Robles, J M Campillo; Ogando, E; Plazaola, F

2007-01-01

Theoretical positron lifetime values have been calculated systematically for most of the elements of the periodic table. Self-consistent and non-self-consistent schemes have been used for the calculation of the electronic structure in the solid, as well as different parametrizations for the positron enhancement factor and correlation energy. The results obtained have been studied and compared with experimental data, confirming the theoretical trends. As is known, positron lifetimes in bulk show a periodic behaviour with atomic number. These calculations also confirm that monovacancy lifetimes follow the same behaviour. The effects of enhancement factors used in calculations have been commented upon. Finally, we have analysed the effects that f and d electrons have on positron lifetimes

Short-Period Binary Stars: Observations, Analyses, and Results

CERN Document Server

Milone, Eugene F; Hobill, David W

2008-01-01

Short-period binaries run the gamut from widely separated stars to black-hole pairs; in between are systems that include neutron stars and white dwarfs, and partially evolved systems such as tidally distorted and over-contact systems. These objects represent stages of evolution of binary stars, and their degrees of separation provide critical clues to how their evolutionary paths differ from that of single stars. The widest and least distorted systems provide astronomers with the essential precise data needed to study all stars: mass and radius. The interactions of binary star components, on the other hand, provide a natural laboratory to observe how the matter in these stars behaves under different and often varying physical conditions. Thus, cataclysmic variables with and without overpoweringly strong magnetic fields, and stars with densities from that found in the Sun to the degenerate matter of white dwarfs and the ultra-compact states of neutron stars and black holes are all discussed. The extensive inde...

Non-periodic homogenization of 3-D elastic media for the seismic wave equation

Science.gov (United States)

Cupillard, Paul; Capdeville, Yann

2018-05-01

Because seismic waves have a limited frequency spectrum, the velocity structure of the Earth that can be extracted from seismic records has a limited resolution. As a consequence, one obtains smooth images from waveform inversion, although the Earth holds discontinuities and small scales of various natures. Within the last decade, the non-periodic homogenization method shed light on how seismic waves interact with small geological heterogeneities and `see' upscaled properties. This theory enables us to compute long-wave equivalent density and elastic coefficients of any media, with no constraint on the size, the shape and the contrast of the heterogeneities. In particular, the homogenization leads to the apparent, structure-induced anisotropy. In this paper, we implement this method in 3-D and show 3-D tests for the very first time. The non-periodic homogenization relies on an asymptotic expansion of the displacement and the stress involved in the elastic wave equation. Limiting ourselves to the order 0, we show that the practical computation of an upscaled elastic tensor basically requires (i) to solve an elastostatic problem and (ii) to low-pass filter the strain and the stress associated with the obtained solution. The elastostatic problem consists in finding the displacements due to local unit strains acting in all directions within the medium to upscale. This is solved using a parallel, highly optimized finite-element code. As for the filtering, we rely on the finite-element quadrature to perform the convolution in the space domain. We end up with an efficient numerical tool that we apply on various 3-D models to test the accuracy and the benefit of the homogenization. In the case of a finely layered model, our method agrees with results derived from Backus. In a more challenging model composed by a million of small cubes, waveforms computed in the homogenized medium fit reference waveforms very well. Both direct phases and complex diffracted waves are

Menstrual experiences and beliefs: a multicountry study of relationships with fertility and fertility regulating methods.

Science.gov (United States)

Severy, L J; Thapa, S; Askew, I; Glor, J

1993-01-01

Knowledge is needed about what women generally experience (behavior and beliefs about sexual, personal, social, and dietary factors) during menstruation as baseline data. Data were obtained from a WHO non nationally representative sample of 5322 parous women from 14 cultural groups between 1973 to 1980 and a subsample of 500 women with detailed daily diaries from 10 countries (Egypt, India, Indonesia, jamaica, Korea, Mexico, Pakistan, Philippines, UK, and Yugoslavia). This study identified and analyzed 1) critical variables through principal component analysis and varimax rotation, 2) clusters of types of women with particular menstrual experiences and particular beliefs, and 3) the relationship between demographic variables and the 2 resultant cluster and the relationship between beliefs and experiences. Factor analysis resulted in the identification of 6 factors and 13 variables which accounted for more than 65% of the variance: amount of bleeding, activity during the last menstrual period, mood during last menstrual period, discomfort during last menstrual period, predictability, and blood characteristics (smell and color). Beliefs that explained more than 53% of the estimated variance were bathing behavior during menstruation, fertility and femininity issues, interpretations and implications of menstruation, and beliefs about not washing hair or body during menstruation. Alpha estimates of reliability for the belief ranged from .33 to .73, and for behavior the range was .40 to .59. The cluster analysis of type of persons identified 3 groups of women: type I (26.4%) who experienced low blood loss the first day and had a long duration of bleeding; type II (52.3%) who had a short duration of bleeding; and type III (21.2%) who had the heaviest bleeding and longest duration of bleeding. The cluster analysis of women's belief types indicated 9 profiles. For instance, Type 2 women tended to believe that menstruation is dirty but prefer more blood loss. Belief Profiles

Increasing Diversity in Emerging Non-religious Communities

Directory of Open Access Journals (Sweden)

Christopher Hassall

2014-12-01

Full Text Available Contemporary growth in non-religious populations has given rise to novel communities with unique perspectives on social issues. We describe a study of diversity within speakers at conferences organised by and attended by the atheist community. We analyse trends in diversity of 630 speakers, corresponding to 1223 speaking slots at 48 conferences conducted for the purpose of discussing or espousing non-religious views over the period 2003–2014. Diversity among speakers (defined using multivariate statistics in terms of the representation of women and non-white people increased significantly over time during the period studied. This broadening participation may have arisen from interventions to address issues of representation or may simply reflect a generational shift in the demographics of the community. However, on-going problems with data collection and the imbalance in the social cost of identifying as non-religious between different social groups continue to impede efforts to reduce barriers to equality within this growing movement.

Prefrontal activity during response inhibition decreases over time in the postpartum period.

Science.gov (United States)

Bannbers, Elin; Gingnell, Malin; Engman, Jonas; Morell, Arvid; Sylvén, Sara; Skalkidou, Alkistis; Kask, Kristiina; Bäckström, Torbjörn; Wikström, Johan; Poromaa, Inger Sundström

2013-03-15

The postpartum period is characterized by complex hormonal changes, but human imaging studies in the postpartum period have thus far predominantly focused on the neural correlates of maternal behavior or postpartum depression, whereas longitudinal studies on neural correlates of cognitive function across the postpartum period in healthy women are lacking. The aim of this study was to longitudinally examine response inhibition, as a measure of executive function, during the postpartum period and its neural correlates in healthy postpartum women and non-postpartum controls. Thirteen healthy postpartum women underwent event-related functional magnetic resonance imaging while performing a Go/NoGo task. The first assessment was made within 48 h of delivery, and the second at 4-7 weeks postpartum. In addition, 13 healthy women examined twice during the menstrual cycle were included as non-postpartum controls. In postpartum women region of interest analyses revealed task-related decreased activations in the right inferior frontal gyrus, right anterior cingulate, and bilateral precentral gyri at the late postpartum assessment. Generally, postpartum women displayed lower activity during response inhibition in the bilateral inferior frontal gyri and precentral gyri compared to non-postpartum controls. No differences in performance on the Go/NoGo task were found between time-points or between groups. In conclusion, this study has discovered that brain activity in prefrontal areas during a response inhibition task decreases throughout the course of the first postpartum weeks and is lower than in non-postpartum controls. Further studies on the normal adaptive brain activity changes that occur during the postpartum period are warranted. Copyright © 2012 Elsevier B.V. All rights reserved.

Exploratory use of periodic pumping tests for hydraulic characterization of faults

Science.gov (United States)

Cheng, Yan; Renner, Joerg

2018-01-01

Periodic pumping tests were conducted using a double-packer probe placed at four different depth levels in borehole GDP-1 at Grimselpass, Central Swiss Alps, penetrating a hydrothermally active fault. The tests had the general objective to explore the potential of periodic testing for hydraulic characterization of faults, representing inherently complex heterogeneous hydraulic features that pose problems for conventional approaches. Site selection reflects the specific question regarding the value of this test type for quality control of hydraulic stimulations of potential geothermal reservoirs. The performed evaluation of amplitude ratio and phase shift between pressure and flow rate in the pumping interval employed analytical solutions for various flow regimes. In addition to the previously presented 1-D and radial-flow models, we extended the one for radial flow in a system of concentric shells with varying hydraulic properties and newly developed one for bilinear flow. In addition to these injectivity analyses, we pursued a vertical-interference analysis resting on observed amplitude ratio and phase shift between the periodic pressure signals above or below packers and in the interval by numerical modeling of the non-radial-flow situation. When relying on the same model the order of magnitude of transmissivity values derived from the analyses of periodic tests agrees with that gained from conventional hydraulic tests. The field campaign confirmed several advantages of the periodic testing, for example, reduced constraints on testing time relative to conventional tests since a periodic signal can easily be separated from changing background pressure by detrending and Fourier transformation. The discrepancies between aspects of the results from the periodic tests and the predictions of the considered simplified models indicate a hydraulically complex subsurface at the drill site that exhibits also hydromechanical features in accord with structural information

Prediction of leakage current of non-ceramic insulators in early aging period

Energy Technology Data Exchange (ETDEWEB)

El-Hag, Ayman H. [Electrical Engineering Department, American University of Sharjah, Sharjah (United Arab Emirates); Jahromi, Ali Naderian [Kinectrics Inc., Transmission and Distribution Technologies, Toronto (Canada); Sanaye-Pasand, Majid [Electrical and Computer Engineering Department, University of Tehran (Iran)

2008-10-15

The paper presents a neural network based prediction technique for the leakage current (LC) of non-ceramic insulators during salt-fog test. Nearly 50 distribution class silicone rubber (SIR) insulators with three different voltage classes have been tested in a salt-fog chamber, where the LC has been continuously recorded for at least 100 h. A boundary for early aging period is defined by the rate of change of the LC instead of a fixed threshold value. Consequently, the Gaussian radial basis network has been adopted to predict the level of LC at the early stage of aging of the SIR insulators and is compared with a classical network. The initial values of LC and its rate of change at 10 min intervals for the first 5 h are selected as the input to the network, and the final value of LC of the early aging period is considered as the output of the network. It is found that Gaussian radial basis function network with a random optimizing training method is an appropriate network to predict the LC with a 3.5-5.3% accuracy, if the training data and the testing data are selected from the same type of SIR insulators. (author)

The nonlinear ambipolar drift and periodic structure of non-self-sustained discharge

International Nuclear Information System (INIS)

Dem'yanov, A.V.; Mazalov, D.A.; Napartovich, A.P.

1995-01-01

Gas discharge is well known to be strongly nonlinear self-organizing system. The diverse nonlinear structures, observed at different conditions (arc, stationary and non-stationary strata, hot spot patterns on the electrodes and so on), are usually explained by the theory taking into account the processes of diffusion and thermoconductivity. In plasma of high pressure discharge these processes become negligible within the characteristic intervals. At these conditions electron drift becomes the main process. Owing to the continuity of full current and plasma quasineutrality there appear effective flows of convective type with the rate depending on the concentration of charged particles. It is this reason that is responsible for the observed structure of the non-moving luminous layers in non-self-sustained discharge in 10%H 2 +Ar mixture under p≥l atm. The present report shows the results of detail experimental and theoretical study of this phenomenon. The experiments have been carried out on the setup with the discharge gap of about 1 cm or of much greater size. Mach-Zender interferometer and an image-converter intensifier operating as a strip or framing camera. The experiments have been carried out under the pressure 1-3 atm. They show that the stationary layers sequentially appear one after another along the direction from the cathode to the anode. Interferometry shows that there is a gas density modulation corresponding to the periodical structure of fringes. The picture of Fig.1 is a typical interferogram, and that of Fig.2 is a gas density distribution restored from it

Formation of organic layer on femtosecond laser-induced periodic surface structures

Energy Technology Data Exchange (ETDEWEB)

Yasumaru, Naoki, E-mail: yasuma@fukui-nct.ac.jp [National Institute of Technology, Fukui College, Sabae, Fukui 916-8507 (Japan); Sentoku, Eisuke [National Institute of Technology, Fukui College, Sabae, Fukui 916-8507 (Japan); Kiuchi, Junsuke [Eyetec Co., Ltd., Sabae, Fukui 916-0016 (Japan)

2017-05-31

Highlights: • Surface analyses of two types of femtosecond laser-induced periodic surface structures (LIPSS) on titanium were conducted. • The parallel-oriented ultrafine LIPSS showed the almost same roughness and chemical states as the non-irradiated Ti surface. • The well-known perpendicular-oriented LIPSS were typically covered with an organic layer similar to a cellulose derivative. - Abstract: Two types of laser-induced periodic surface structures (LIPSS) formed on titanium by femtosecond (fs) laser pulses (λ = 800 nm, τ = 180 fs, ν = 1 kHz) in air were investigated experimentally. At a laser fluence F above the ablation threshold, LIPSS with a minimum mean spacing of D < λ⁄2 were observed perpendicular to the laser polarization direction. In contrast, for F slightly below than the ablation threshold, ultrafine LIPSS with a minimum value of D < λ/10 were formed parallel to the polarization direction. The surface roughness of the parallel-oriented LIPSS was almost the same as that of the non-irradiated surface, unlike the high roughness of the perpendicular-oriented LIPSS. In addition, although the surface state of the parallel-oriented LIPSS was the same as that of the non-irradiated surface, the perpendicular-oriented LIPSS were covered with an organic thin film similar to a cellulose derivative that cannot be easily formed by conventional chemical synthesis. The results of these surface analyses indicate that these two types of LIPSS are formed through different mechanisms. This fs-laser processing technique may become a new technology for the artificial synthesis of cellulose derivatives.

Oscillations of a Beam on a Non-Linear Elastic Foundation under Periodic Loads

Directory of Open Access Journals (Sweden)

Donald Mark Santee

2006-01-01

Full Text Available The complexity of the response of a beam resting on a nonlinear elastic foundation makes the design of this structural element rather challenging. Particularly because, apparently, there is no algebraic relation for its load bearing capacity as a function of the problem parameters. Such an algebraic relation would be desirable for design purposes. Our aim is to obtain this relation explicitly. Initially, a mathematical model of a flexible beam resting on a non-linear elastic foundation is presented, and its non-linear vibrations and instabilities are investigated using several numerical methods. At a second stage, a parametric study is carried out, using analytical and semi-analytical perturbation methods. So, the influence of the various physical and geometrical parameters of the mathematical model on the non-linear response of the beam is evaluated, in particular, the relation between the natural frequency and the vibration amplitude and the first period doubling and saddle-node bifurcations. These two instability phenomena are the two basic mechanisms associated with the loss of stability of the beam. Finally Melnikov's method is used to determine an algebraic expression for the boundary that separates a safe from an unsafe region in the force parameters space. It is shown that this can be used as a basis for a reliable engineering design criterion.

Period Study and Analyses of 2017 Observations of the Totally Eclipsing, Solar Type Binary, MT Camelopardalis

Science.gov (United States)

Faulkner, Danny R.; Samec, Ronald G.; Caton, Daniel B.

2018-06-01

We report here on a period study and the analysis of BVRcIc light curves (taken in 2017) of MT Cam (GSC03737-01085), which is a solar type (T ~ 5500K) eclipsing binary. D. Caton observed MT Cam on 05, 14, 15, 16, and 17, December 2017 with the 0.81-m reflector at Dark Sky Observatory. Six times of minimum light were calculated from four primary eclipses and two secondary eclipses:HJD I = 24 58092.4937±0.0002, 2458102.74600±0.0021, 2458104.5769±0.0002, 2458104.9434±0.0029HJD II = 2458103.6610±0.0001, 2458104.7607±0.0020,Six times of minimum light were also calculated from data taken by Terrell, Gross, and Cooney, in their 2016 and 2004 observations (reported in IBVS #6166; TGC, hereafter). In addition, six more times of minimum light were taken from the literature. From all 18 times of minimum light, we determined the following light elements:JD Hel Min I=2458102.7460(4) + 0.36613937(5) EWe found the orbital period was constant over the 14 years spanning all observations. We note that TGC found a slightly increasing period. However, our results were obtained from a period study rather than comparison of observations from only two epochs by the Wilson-Devinney (W-D) Program. A BVRcIc Johnson-Cousins filtered simultaneous W-D Program solution gives a mass ratio (0.3385±0.0014) very nearly the same as TGC’s (0.347±0.003), and a component temperature difference of only ~40 K. As with TGC, no spot was needed in the modeling. Our modeling (beginning with Binary Maker 3.0 fits) was done without prior knowledge of TGC’s. This shows the agreement achieved when independent analyses are done with the W-D code. The present observations were taken 1.8 years later than the last curves by TGC, so some variation is expected.The Roche Lobe fill-out of the binary is ~13% and the inclination is ~83.5 degrees. The system is a shallow contact W-type W UMa Binary, albeit, the amplitudes of the primary and secondary eclipse are very nearly identical. An eclipse duration of ~21

Detailed semantic analyses of human error incidents occurring at nuclear power plants. Extraction of periodical transition of error occurrence patterns by applying multivariate analysis

International Nuclear Information System (INIS)

Hirotsu, Yuko; Suzuki, Kunihiko; Takano, Kenichi; Kojima, Mitsuhiro

2000-01-01

It is essential for preventing the recurrence of human error incidents to analyze and evaluate them with the emphasis on human factor. Detailed and structured analyses of all incidents at domestic nuclear power plants (NPPs) reported during last 31 years have been conducted based on J-HPES, in which total 193 human error cases are identified. Results obtained by the analyses have been stored into the J-HPES database. In the previous study, by applying multivariate analysis to above case studies, it was suggested that there were several occurrence patterns identified of how errors occur at NPPs. It was also clarified that the causes related to each human error are different depending on age of their occurrence. This paper described the obtained results in respects of periodical transition of human error occurrence patterns. By applying multivariate analysis to the above data, it was suggested there were two types of error occurrence patterns as to each human error type. First type is common occurrence patterns, not depending on the age, and second type is the one influenced by periodical characteristics. (author)

Non-iterative method to calculate the periodical distribution of temperature in reactors with thermal regeneration

International Nuclear Information System (INIS)

Sanchez de Alsina, O.L.; Scaricabarozzi, R.A.

1982-01-01

A matrix non-iterative method to calculate the periodical distribution in reactors with thermal regeneration is presented. In case of exothermic reaction, a source term will be included. A computer code was developed to calculate the final temperature distribution in solids and in the outlet temperatures of the gases. The results obtained from ethane oxidation calculation in air, using the Dietrich kinetic data are presented. This method is more advantageous than iterative methods. (E.G.) [pt

Relationships between menstrual and menopausal attitudes and associated demographic and health characteristics: the Hilo Women's Health Study.

Science.gov (United States)

Morrison, Lynn A; Sievert, Lynnette L; Brown, Daniel E; Rahberg, Nichole; Reza, Angela

2010-07-01

The objective of this study was to examine the relation of menstrual attitudes to menopausal attitudes and the demographic and health characteristics associated with each. This cross-sectional study consisted of a randomly selected sample of 1,824 respondents aged 16 to 100 years in multi-ethnic Hilo, Hawai'i. Women completed questionnaires for demographic and health information, such as age, ethnicity, education, residency in Hawai'i, menopausal status, exercise, and attitudes toward menstruation and menopause. Women more often chose positive terms, such as "natural," to describe menstruation (60.8%) and menopause (59.4%). In bivariate analyses, post-menopausal women were significantly more likely to have positive menstrual and menopausal attitudes than pre-menopausal women. Factor analyses were used to cluster attitudes followed by linear regression to identify demographic characteristics associated with factor scores. Asian-American ethnicity, higher education, reporting more exercise, and growing up outside of Hawai'i were associated with positive menstrual attitudes. Higher education, older age, post-menopausal status, growing up outside of Hawai'i and having hot flashes were associated with positive menopausal attitudes. Bivariate correlation analyses suggested significant associations between factor scores for menstrual and menopausal attitudes. Both negative and positive menstrual attitudes were positively correlated with the anticipation of menopause, although negative attitudes toward menstruation were negatively correlated with menopause as a positive, natural life event. Demographic variables, specifically education and where one grows up, influenced women's attitudes toward menstruation and menopause and should be considered for inclusion in subsequent multi-ethnic studies. Further research is also warranted in assessing the relationship between menstrual and menopausal attitudes.

Plasma lipid peroxidation, blood GSH concentration and erythrocyte antioxidant enzymes in menstruating females with ovulatory and anovulatory cycles compared with males

Directory of Open Access Journals (Sweden)

G Lutosławska

2003-12-01

Full Text Available This study was undertaken to evaluate plasma TBARS and blood GSH concentration and erythrocyte antioxidant enzymes (glutathione peroxidase, catalase and superoxide dismutase in active, regularly menstruating female physical education students with ovulatory and anovulatory menstrual cycles and in their male counterparts. A total of 27 subjects (12 males and 15 females volunteered to participate in the study. All females were regularly menstruating with cycle length between 26-31 days. Plasma progesterone and 17-β-estradiol concentrations were assayed during the 7th-9th and 22nd-25th day of the menstrual cycle. Women with plasma progesterone concentration exceeding 19 nmol•l-1 during the 22nd-25th day were referred to as ovulatory (Group OV; n=7. Women without a peak plasma progesterone concentration were referred to as anovulatory (Group AN; n=8. Blood from male subjects was withdrawn twice - two weeks apart, at their convenience. It was found that the menstrual cycle phases did not affect plasma TBARS and blood glutathione concentration and erythrocyte GPX, CAT and SOD activity. However, erythrocyte GPX activity either in ovulatory or anovulatory women was by about 30% higher than in male subjects. Erythrocyte SOD activity in ovulatory women both in follicular and luteal phase of the menstrual cycle (1557 U/g Hb and 1394.6 U/g Hb, respectively was markedly lower than in men (1951.8 and 1937.7 U/g Hb for blood sampling I and II, respectively. In contrast, erythrocyte SOD activity in anovulatory women (1855.5 U/g Hb and 1745.7 U/g Hb in the follicular and luteal phases, respectively was similar to that found in men. The above data indicated that erythrocyte GPX and SOD activities are sensitive to plasma ovarian hormone concentration. In addition, they suggested that due to higher erythrocyte GPX activity females even with anovulatory menstrual cycles are protected better than males against hydrogen peroxide action. However, lower superoxide

Influencing factors of dysmenorrhoea among hospital nurses: a questionnaire survey in Taiwan.

Science.gov (United States)

Chiu, Min-Hui; Hsieh, Hsiu-Fen; Yang, Yi-Hsin; Chen, Huei-Mein; Hsu, Su-Chen; Wang, Hsiu-Hung

2017-12-19

Nurses are at high risk of dysmenorrhoea while working with patients. The study objectives were to: (1) describe the demographic and menstruation characteristics of dysmenorrhoea, knowledge about dysmenorrhoea and menstrual attitudes towards menstruation among dysmenorrhoeal and non-dysmenorrhoeal hospital nurses; (2) identify significant differences between the groups; and (3) examine factors influencing dysmenorrhoea. This cross-sectional survey used a structured questionnaire, administered at two hospitals in southern Taiwan. Participants included hospital nurses at least 18 years of age who agreed to participate. All participants were recruited through random sampling. The questionnaire included demographic data, the Dysmenorrhoea Knowledge Scale and Menstrual Attitude Scale (MAS). A total of 420 nurses completed the questionnaire. Among them, 297 (70.7%) had experienced dysmenorrhoea in the past 6 months and 123 (29.3%) had not. Significant differences in age (P<0.001), marital status (P<0.001), childbearing status (P<0.001), age at menarche (P<0.05) and rotating three shift ratio (P<0.05) were identified between the dysmenorrhoea and non-dysmenorrhoea groups. Analysis of the MAS results revealed significant differences between the groups regarding consideration of menstruation as a debilitating (P<0.001) or bothersome event (P<0.05), anticipation and prediction of menstruation onset (P<0.01) and denial of any effects from menstruation (P<0.001). Results of the multiple logistic regression showed that predictive factors included age <40 years (4.46 vs 1.00), working three shift rotations (2.07 vs 1.00), marital status (2.59 vs 1.00), acknowledging menstruation as a debilitating event (2.72 vs 1.00) and denial of effects from menstruation (2.59 vs 1.00). These findings could help nursing managers to create a caring and friendly work environment for hospital nurses at risk of dysmenorrhoea. © Article author(s) (or their employer(s) unless otherwise stated in

Ecological stages of the Venice Lagoon analysed using landing time series data

Science.gov (United States)

Libralato, Simone; Pranovi, Fabio; Raicevich, Saša; Da Ponte, Filippo; Giovanardi, Otello; Pastres, Roberto; Torricelli, Patrizia; Mainardi, Danilo

2004-11-01

The time series of landings in the Venice Lagoon from 1945 to 2001 were analysed with the aim of explaining the ecosystem changes occurred. The comparative analysis of the total landings and mean Trophic Level (mTL) time series allowed to identify four different stages in the lagoon ecosystem. The first period, from 1945 to 1973, was characterised by increasing trends in the landings and their mTL. The second one, from 1974 to 1989, showed a decrease in the landings but still an increase in the mTL. The third period, from 1990 to 1998, had again a positive trend in the landings, but the mTL showed a sharp decline. After 1998, a slight decreasing trend in both mTL and landings was observed: the analyses of the artisanal fishery landings only date back to 1995 this effect. The presence of four distinct periods was also confirmed by the analysis of the trends of other indices estimated using landings data: the Fishing in Balance index (FiB), the Trophic Efficiency (TE) and the Pelagic on Demersal landings ratio (P/D). In the first period, the increasing fishing pressure, along with no evidence of ecosystem crisis, suggested that an increased nutrient discharge was supporting it; analogously, the bottom-up effects had driven the dynamics of the ecosystem also in the second period, when the decrease in nutrient loads caused a shift of the primary producers from planktonic to macrobenthic. The spreading of the Manila clam, a non-native species, and the development of its massive mechanical exploitation have been the main forces driving the ecosystem during the third period, for which, however, no signs of crises were detected. The fourth period showed evidence of the "fishing down the food web" effect. Possible causes of such an effect were investigated and allowed us to conclude that not overfishing, but the effects of mechanical harvesting of the Manila clam had caused relevant impacts on habitat and benthic communities, concluding that the present level of

Periodic Hamiltonian hierarchies and non-uniqueness of ...

Indian Academy of Sciences (India)

2016-12-02

Dec 2, 2016 ... Ca. 1. Introduction. Through the past few decades, research in supersym- ... The subject of periodic Hamiltonians has been exam- ined for a long time ... The plan of this paper is as follows: In §2, a brief resume of SUSYQM is ...

[Effect of antecedent dry period on water quality of urban storm runoff pollution].

Science.gov (United States)

Bian, Bo

2009-12-01

Identified the main factor influencing urban rainfall-runoff pollution provides a scientific basis for urban rainfall-runoff pollution control and management. Therefore, starting in May 2006, a study was conducted to characterize water quality from representative land uses types in Zhenjiang to analyse the effect of antecedent dry period on stormwater runoff quality. The results show that the beginning of rainfall, with the increase of antecedent dry periods, the percentages of less than 40 microm is increased, the correlation of the water quality parameters (TN, TP, Zn, Pb, Cu, TSS and COD) and antecedent dry period shows a significant positive correlation, dissolved pollutants in the initial period surface runoff is increased. These findings show that facilitating the recognition of antecedent dry periods is the main factor influencing the change in concentration and partitioning of pollutants to provide the scientific basis for non-point source pollution control and management.

Comparison of Reflexology and Connective Tissue Manipulation in Participants with Primary Dysmenorrhea.

Science.gov (United States)

Demirtürk, Funda; Erkek, Zümrüt Yilar; Alparslan, Özgür; Demirtürk, Fazlı; Demir, Osman; Inanir, Ahmet

2016-01-01

The aim of this interventional correlational study is to compare the effects of foot reflexology (FR) and connective tissue manipulation (CTM) in subjects with primary dysmenorrhea. A total of 30 participants having primary dysmenorrhea completed the study. Data, including demographics (age, body-mass index), menstrual cycle (age at menarche, menstrual cycle duration, time since menarche, bleeding duration), and menstrual pain characteristics (intensity and duration of pain, type and amount of analgesics), were recorded. Effect of dysmenorrhea on participants' concentration in lessons and in sports and social activities was assessed by using the visual analog scale. Participants rated their menstruation-related symptom intensity through the Likert-type scale. FR was applied to 15 participants for 3 days a week and CTM was performed on 15 participants for 5 days a week. Treatments were performed during one cycle, which started at the third or fourth day of menstruation and continued till the onset of next menstruation. Assessments were performed before treatment (first menstruation), then after termination of the treatment because of the next menstruation's onset (second menstruation), and ∼1 month after at the consecutive menstrual period (third menstrual cycle). Time-dependent changes in duration and intensity of pain along with analgesic amount show that both treatments provided significant improvements (p  0.05). A similar result was obtained in terms of time-dependent changes in concentration in lessons and difficulty in sports and social activities due to dysmenorrhea. Menstruation-related symptoms were found to be decreased after treatment and in the following cycle with both treatments (p  0.05). Both FR and CTM can be used in the treatment of primary dysmenorrhea and menstruation-related symptoms as these methods are free from the potentially adverse effects of analgesics, noninvasive, and easy to perform.

Analyse de l'emballement thermique d'un système chimique hybride non tempéré

OpenAIRE

Véchot , Luc; Bigot , Jean-Pierre; Minko , Wilfried ,; Kazmierczak , Marc; Vicot , Patricia

2009-01-01

National audience; Ce travail s'intéresse au “blow-down” (emballement thermique en présence d'un évent de sécurité) d'un système chimique non tempéré (30% CHP) soumis à un incendie. Il utilise une maquette à l'échelle 0,1 l. L'analyse des données post décomposition a montré que la vapeur présente est principalement un produit de la réaction. Toutes les expériences de blow-down ont présenté deux pics de pression, quel que soit le rapport A/V, ce qui est typique des systèmes non tempérés. Nous ...

Introduction and application of non-stationary standardized precipitation index considering probability distribution function and return period

Science.gov (United States)

Park, Junehyeong; Sung, Jang Hyun; Lim, Yoon-Jin; Kang, Hyun-Suk

2018-05-01

The widely used meteorological drought index, the Standardized Precipitation Index (SPI), basically assumes stationarity, but recent changes in the climate have led to a need to review this hypothesis. In this study, a new non-stationary SPI that considers not only the modified probability distribution parameter but also the return period under the non-stationary process was proposed. The results were evaluated for two severe drought cases during the last 10 years in South Korea. As a result, SPIs considered that the non-stationary hypothesis underestimated the drought severity than the stationary SPI despite that these past two droughts were recognized as significantly severe droughts. It may be caused by that the variances of summer and autumn precipitation become larger over time then it can make the probability distribution wider than before. This implies that drought expressions by statistical index such as SPI can be distorted by stationary assumption and cautious approach is needed when deciding drought level considering climate changes.

Cold-Fluid Equilibrium of a Large-Aspect-Ratio Ellipse-Shaped Charged-Particle Beam in a Non-Axisymmetric Periodic Permanent Magnet Focusing Field

CERN Document Server

Zhou, Jing; Chen Chi Ping

2005-01-01

A new class of equilibrium is discovered for a large-aspect-ratio ellipse-shaped charged-particle beam in a non-axisymmetric periodic permanent magnet focusing field. A paraxial cold-fluid model is employed to derive the equilibrium flow properties and generalized envelope equations with negligibly small emittance. A periodic beam equilibrium solution is obtained numerically from the generalized envelope equations. It is shown that the beam edges are well confined in both transverse directions, and that the equilibrium beam exhibits a small-angle periodic wobble as it propagates. A two-dimensional particle-in-cell (PIC) code, PFB2D, is used to verify the theoretical predictions in the paraxial limit, and to establish validity under non-paraxial situations and the influence of the conductor walls of the beam tunnel.

Determinants of appetite ratings: the role of age, gender, BMI, physical activity, smoking habits, and diet/weight concern1 At the time of the study, Anne Flint was employed at the Department of Human Nutrition, The Royal Veterinary and Agricultural University, Copenhagen.

Directory of Open Access Journals (Sweden)

Anne Flint

2011-08-01

Full Text Available Appetite measures are often recorded by visual analogue scales (VAS, and are assumed to reflect central nervous system (CNS perceptions and sensations. However, little is known about how physiological, psychological, social, and cultural factors influence VAS.To investigate whether age, gender, body mass index (BMI, smoking habits, physical activity, diet behaviour, and menstruation cycle are determinants of appetite ratings.We investigated appetite ratings in different groups of a population during a single meal test, including 178 healthy women (98 and men (80, aged 20–60 years with a BMI of 18.5–35.0 kg/m2. Subjects consumed an evening meal composed to meet individual requirements of energy content and recommendations regarding macronutrient composition. Before and every half hour until 3 hours after the meal, subjects filled out VAS for satiety, fullness, hunger, and prospective food intake. They also filled in a questionnaire on eating/slimming behaviour.Multiple linear regression analyses showed that gender and age were the most powerful predictors of postprandial satiety (p<0.001, adj. R 2=0.19 and hunger (p<0.001, adj. R 2=0.15. Repeated measures general linear model (GLM analyses revealed that women felt more satisfied than men (p<0.001 and older subjects felt more satisfied than younger (p<0.01. Furthermore, light/no exercisers felt more satisfied and less hungry than hard/moderate exercisers (p<0.05, but these differences disappeared after adjusting for age and gender. Smokers rated their prospective consumption lower than non-smokers (p < 005 and women in the ovulation phase felt less hungry than women in the menstruation phase (p<005. Neither BMI nor diet/weight concern were significantly associated with appetite ratings.Appetite ratings differed according to age, gender, and physical activity and to a lesser degree for smoking habits and menstruation cycle. Appetite ratings were not influenced by BMI and diet/weight concern

Spatial coherence of flood-rich and flood-poor periods across Germany

Science.gov (United States)

Merz, Bruno; Dung, Nguyen Viet; Apel, Heiko; Gerlitz, Lars; Schröter, Kai; Steirou, Eva; Vorogushyn, Sergiy

2018-04-01

Despite its societal relevance, the question whether fluctuations in flood occurrence or magnitude are coherent in space has hardly been addressed in quantitative terms. We investigate this question for Germany by analysing fluctuations in annual maximum series (AMS) values at 68 discharge gauges for the common time period 1932-2005. We find remarkable spatial coherence across Germany given its different flood regimes. For example, there is a tendency that flood-rich/-poor years in sub-catchments of the Rhine basin, which are dominated by winter floods, coincide with flood-rich/-poor years in the southern sub-catchments of the Danube basin, which have their dominant flood season in summer. Our findings indicate that coherence is caused rather by persistence in catchment wetness than by persistent periods of higher/lower event precipitation. Further, we propose to differentiate between event-type and non-event-type coherence. There are quite a number of hydrological years with considerable non-event-type coherence, i.e. AMS values of the 68 gauges are spread out through the year but in the same magnitude range. Years with extreme flooding tend to be of event-type and non-coherent, i.e. there is at least one precipitation event that affects many catchments to various degree. Although spatial coherence is a remarkable phenomenon, and large-scale flooding across Germany can lead to severe situations, extreme magnitudes across the whole country within one event or within one year were not observed in the investigated period.

NUMERICAL MODELLING AS NON-DESTRUCTIVE METHOD FOR THE ANALYSES AND DIAGNOSIS OF STONE STRUCTURES: MODELS AND POSSIBILITIES

Directory of Open Access Journals (Sweden)

Nataša Štambuk-Cvitanović

1999-12-01

Full Text Available Assuming the necessity of analysis, diagnosis and preservation of existing valuable stone masonry structures and ancient monuments in today European urban cores, numerical modelling become an efficient tool for the structural behaviour investigation. It should be supported by experimentally found input data and taken as a part of general combined approach, particularly non-destructive techniques on the structure/model within it. For the structures or their detail which may require more complex analyses three numerical models based upon finite elements technique are suggested: (1 standard linear model; (2 linear model with contact (interface elements; and (3 non-linear elasto-plastic and orthotropic model. The applicability of these models depend upon the accuracy of the approach or type of the problem, and will be presented on some characteristic samples.

Relationships between menstrual and menopausal attitudes and associated demographic and health characteristics: The Hilo Women’s Health Study

Science.gov (United States)

Sievert, Lynnette L.; Brown, Daniel E.; Rahberg, Nichole; Reza, Angela

2010-01-01

The objective of this study was to examine the relation of menstrual attitudes to menopausal attitudes and the demographic and health characteristics associated with each. This cross-sectional study consisted of a randomly selected sample of 1824 respondents aged 16 to 100 years in multi-ethnic Hilo, Hawai`i. Women completed questionnaires for demographic and health information, such as age, ethnicity, education, residency in Hawai`i, menopausal status, exercise, and attitudes toward menstruation and menopause. Women more often chose positive terms, such as “natural,” to describe menstruation (60.8%) and menopause (59.4%). In bivariate analyses, post-menopausal women were significantly more likely to have positive menstrual and menopausal attitudes than pre-menopausal women. Factor analyses were used to cluster attitudes followed by linear regression to identify demographic characteristics associated with factor scores. Asian-American ethnicity, higher education, reporting more exercise, and growing up outside of Hawai`i were associated with positive menstrual attitudes. Higher education, older age, post-menopausal status, growing up outside of Hawai`i and having hot flashes were associated with positive menopausal attitudes. Bivariate correlation analyses suggested significant associations between factor scores for menstrual and menopausal attitudes. Both negative and positive menstrual attitudes were positively correlated with the anticipation of menopause, although negative attitudes toward menstruation were negatively correlated with menopause as a positive, natural life event. Demographic variables, specifically education and where one grows up, influenced women’s attitudes toward menstruation and menopause and should be considered for inclusion in subsequent multi-ethnic studies. Further research is also warranted in assessing the relationship between menstrual and menopausal attitudes. PMID:20853216

Plasma chemistry of the chinstrap penguin Pygoscelis antarctica during fasting periods: A case of poor adaptation to food deprivation?

OpenAIRE

Alonso-Álvarez, Carlos; Ferrer, Miguel; Viñuela, Javier; Amat, Juan A.

2003-01-01

The chinstrap penguin (Pygoscelis antarctica) is the smallest penguin species to be used to study the physiology of fasting. We analysed body-mass change and plasma chemistry of five non-breeding chinstraps during an experimental fasting period in the breeding season. We also analysed the same parameters in six fasting birds under natural conditions (during an incubation shift, which lasts about 10 days). Both groups presented similar patterns of change, showing a rapid increase in urea and u...

Trio of terror (pregnancy, menstruation, and breastfeeding): an existential function of literal self-objectification among women.

Science.gov (United States)

Morris, Kasey Lynn; Goldenberg, Jamie L; Heflick, Nathan A

2014-07-01

Research and theorizing suggest that objectification entails perceiving a person not as a human being but, quite literally, as an object. However, the motive to regard the self as an object is not well understood. The current research tested the hypothesis that literal self-objectification can serve a terror management function. From this perspective, the female body poses a unique existential threat on account of its role in reproduction, and regarding the self as an object is posited to shield women from this threat because objects, in contrast to humans, are not mortal. Across 5 studies, 3 operationalizations of literal self-objectification were employed (a denial of essentially human traits to the self, overlap in the explicit assignment of traits to the self and objects, and implicit associations between self and objects using an implicit association test) in response to 3 aspects of women's bodies involved in reproduction (pregnancy, menstruation, and breastfeeding). In each study, priming mortality led women (but not men, included in Studies 1, 3, 4, and 5) to literally self-objectify in conditions where women's reproductive features were salient. In addition, literal self-objectification was found to mediate subsequent responsiveness to death-related stimuli (Study 4). Together, these findings are the first to demonstrate a direct link between mortality salience, women's role in reproduction, and their self-objectification, supporting an existential function of self-objectification in women.

Long-period Intensity Pulsations in Coronal Loops Explained by Thermal Non-equilibrium Cycles

Energy Technology Data Exchange (ETDEWEB)

Froment, C.; Auchère, F.; Bocchialini, K.; Buchlin, E.; Solomon, J. [Institut d’Astrophysique Spatiale, CNRS, Univ. Paris-Sud, Université Paris-Saclay, Bât. 121, F-91405 Orsay cedex (France); Aulanier, G. [LESIA, Observatoire de Paris, PSL Research University, CNRS, Sorbonne Universités, UPMC Univ. Paris 06, Univ. Paris Diderot, Sorbonne Paris Cité, 5 place Jules Janssen, F-92195 Meudon (France); Mikić, Z., E-mail: clara.froment@astro.uio.no [Predictive Science, Inc., San Diego, CA 92121 (United States)

2017-02-01

In solar coronal loops, thermal non-equilibrium (TNE) is a phenomenon that can occur when the heating is both highly stratified and quasi-constant. Unambiguous observational identification of TNE would thus permit us to strongly constrain heating scenarios. While TNE is currently the standard interpretation of coronal rain, the long-term periodic evolution predicted by simulations has never been observed. However, the detection of long-period intensity pulsations (periods of several hours) has been recently reported with the Solar and Heliospheric Observatory /EIT, and this phenomenon appears to be very common in loops. Moreover, the three intensity-pulsation events that we recently studied with the Solar Dynamics Observatory /Atmospheric Imaging Assembly (AIA) show strong evidence for TNE in warm loops. In this paper, a realistic loop geometry from linear force-free field (LFFF) extrapolations is used as input to 1D hydrodynamic simulations. Our simulations show that, for the present loop geometry, the heating has to be asymmetrical to produce TNE. We analyze in detail one particular simulation that reproduces the average thermal behavior of one of the pulsating loop bundle observed with AIA. We compare the properties of this simulation with those deduced from the observations. The magnetic topology of the LFFF extrapolations points to the presence of sites of preferred reconnection at one footpoint, supporting the presence of asymmetric heating. In addition, we can reproduce the temporal large-scale intensity properties of the pulsating loops. This simulation further strengthens the interpretation of the observed pulsations as signatures of TNE. This consequently provides important information on the heating localization and timescale for these loops.

Analysis of a commitment period reserve at national and global levels

DEFF Research Database (Denmark)

Missfeldt, F.; Haites, E.

2002-01-01

of (a) X% of five times the Party's most recently reviewed emissions inventory; and (b) Y% of the Party's initial assigned amount. The agreement reached at the resumed sixth session of the Conference of the Parties (COP) sets X = 100% and Y = 90%. This paper analyses different specifications (values...... of X and Y) of the commitment period reserve in terms of potential non-compliance due to overselling and restricted sales of quota surplus to compliance needs of the seller. To eliminate potential non-compliance due to overselling, Y must be equal to 100% and X must be greater than 105%. Specifications...... that limit potential non-compliance due to overselling, may temporarily restrict sales of quota surplus to the compliance of some countries. The Annex II Parties are less likely to face restrictions on sales of surplus quota than other Annex B countries. The risk of temporarily restricted sales is reduced...

Non-radial oscillations of rotating stars and their relevance to the short-period oscillations of cataclysmic variables

International Nuclear Information System (INIS)

Papaloizou, J.; Pringle, J.E.

1978-01-01

The usual hypothesis, that the short-period coherent oscillations seen in cataclysmic variables are attributable to g modes in a slowly rotating white dwarf, is considered. It is shown that this hypothesis is untenable for three main reasons: (i) the observed periods are too short for reasonable white dwarf models, (ii) the observed variability of the oscillations is too rapid and (iii) the expected rotation of the white dwarf, due to accretion, invalidates the slow rotation assumption on which standard g-mode theory is based. The low-frequency spectrum of a rotating pulsating star is investigated taking the effects of rotation fully into account. In this case there are two sets of low-frequency modes, the g modes, and modes similar to Rossby waves in the Earth's atmosphere and oceans, which are designated r modes. Typical periods for such modes are 1/m times the rotation period of the white dwarfs outer layers (m is the aximuthal wavenumber). It is concluded that non-radial oscillations of rotating white dwarfs can account for the properties of the oscillations seen in dwarf novae. Application of these results to other systems is also discussed. (author)

Sensitivity analyses of biodiesel thermo-physical properties under diesel engine conditions

DEFF Research Database (Denmark)

Cheng, Xinwei; Ng, Hoon Kiat; Gan, Suyin

2016-01-01

This reported work investigates the sensitivities of spray and soot developments to the change of thermo-physical properties for coconut and soybean methyl esters, using two-dimensional computational fluid dynamics fuel spray modelling. The choice of test fuels made was due to their contrasting...... saturation-unsaturation compositions. The sensitivity analyses for non-reacting and reacting sprays were carried out against a total of 12 thermo-physical properties, at an ambient temperature of 900 K and density of 22.8 kg/m3. For the sensitivity analyses, all the thermo-physical properties were set...... as the baseline case and each property was individually replaced by that of diesel. The significance of individual thermo-physical property was determined based on the deviations found in predictions such as liquid penetration, ignition delay period and peak soot concentration when compared to those of baseline...

Weaning from non-invasive positive pressure ventilation: Experience with progressive periods of withdraw

Directory of Open Access Journals (Sweden)

C. Damas

2008-01-01

Full Text Available Background: In recent years non-invasive ventilation (NIV as become a valuable therapeutic option in exacerbations of patients with chronic pulmonary obstructive disease. Although widely used there is a paucity of information on weaning from NIV. Objectives: We aimed to describe the performance of a weaning protocol based on progressive periods of NIV withdraw. Methods: During a one year period we performed NIV in 78 patients with acute exacerbation of chronic respiratory failure. Weaning was considered in patients with 24 hours without acidosis and respiratory rate less than 25 cycles per minute. Weaning was performed as following: during the first 24 hours in each 3 hours, one hour without NIV (except during night period, in the second day in each 3 hours, two hours without NIV (except during night period and in the third day NIV was used during the night period. Results: Sixty five patients began the weaning protocol. Mean NIV time was 120,9 hours (17 to 192 hours. No adverse effects were recorded in patients who began the weaning protocol. All patients completed the weaning protocol with no re-institution of NIV or invasive ventilation during hospitalization. Conclusions: We report an excellent weaning success rate of NIV in patients with acute severe exacerbation of CRF. Although our weaning protocol required 72 hours, our results suggest that strategies based on periods with and with-out NIV are effective. Weather similar less time consuming weaning strategies are effective, merits investigation. Resumo: Introdução: Nos últimos anos, a ventilação não invasiva (VNI tornou-se numa opção terapêutica válida nas exacerbações agudas de doentes com doença pulmonar crónica obstrutiva. No entanto, apesar de muito utilizada, existe muito pouca informação sobre o desmame deste modo ventilatório. Objectivos: Descrever um protocolo de desmame baseado em períodos progressivos de descontinuação de VNI. Métodos: Durante um ano foram

Non-destructive NIR-FT-Raman analyses in practice. Part I. Analyses of plants and historic textiles.

Science.gov (United States)

Andreev, G N; Schrader, B; Schulz, H; Fuchs, R; Popov, S; Handjieva, N

2001-12-01

Non-destructive analysis of natural substances in plants as well as of old dyed textiles by Raman spectroscopy has not been possible using conventional techniques. Exciting lines from the visible part of the spectrum produced photochemical and thermal decomposition of the objects as well as strong fluorescence. Using Nd:YAG laser excitation at 1,064 nm together with a special sample arrangement and interferometric recording, various polyacetylenes in Aethusa cynapium and in chamomile (Chamomilla recutita) and the main valuable substances in gentian species (Gentiana lutea and G. punctata), curcuma roots (Curcuma longa), cinnamon (Cinnamomum zeylanicum), fennel (Foeniculum vulgare), clove (Caryophyllus aromaticus), and ginger (Zingiber officinale) were analyzed non-destructively and discussed in comparison with the corresponding pure standard compounds. We further analyzed non-destructively the FT Raman spectra of collections of historical textiles and lakes used for dyeing. It is possible to distinguish the main dye component non-destructively by using Raman bands.

Determinants of appetite ratings: the role of age, gender, BMI, physical activity, smoking habits, and diet/weight concern.

Science.gov (United States)

Gregersen, Nikolaj T; Møller, Bente K; Raben, Anne; Kristensen, Søren T; Holm, Lotte; Flint, Anne; Astrup, Arne

2011-01-01

Appetite measures are often recorded by visual analogue scales (VAS), and are assumed to reflect central nervous system (CNS) perceptions and sensations. However, little is known about how physiological, psychological, social, and cultural factors influence VAS. To investigate whether age, gender, body mass index (BMI), smoking habits, physical activity, diet behaviour, and menstruation cycle are determinants of appetite ratings. We investigated appetite ratings in different groups of a population during a single meal test, including 178 healthy women (98) and men (80), aged 20-60 years with a BMI of 18.5-35.0 kg/m(2). Subjects consumed an evening meal composed to meet individual requirements of energy content and recommendations regarding macronutrient composition. Before and every half hour until 3 hours after the meal, subjects filled out VAS for satiety, fullness, hunger, and prospective food intake. They also filled in a questionnaire on eating/slimming behaviour. Multiple linear regression analyses showed that gender and age were the most powerful predictors of postprandial satiety (pdifferences disappeared after adjusting for age and gender. Smokers rated their prospective consumption lower than non-smokers (pdiffered according to age, gender, and physical activity and to a lesser degree for smoking habits and menstruation cycle. Appetite ratings were not influenced by BMI and diet/weight concern. These factors should be considered when planning studies and analysing data concerning appetite sensations.

Non-equilibrium ionization by a periodic electron beam. II. Synthetic Si IV and O IV transition region spectra

Science.gov (United States)

Dzifčáková, Elena; Dudík, Jaroslav

2018-03-01

Context. Transition region (TR) spectra typically show the Si IV 1402.8 Å line to be enhanced by a factor of 5 or more compared to the neighboring O IV 1401.2 Å, contrary to predictions of ionization equilibrium models and the Maxwellian distribution of particle energies. Non-equilibrium effects in TR spectra are therefore expected. Aims: To investigate the combination of non-equilibrium ionization and high-energy particles, we apply the model of the periodic electron beam, represented by a κ-distribution that recurs at periods of several seconds, to plasma at chromospheric temperatures of 104 K. This simple model can approximate a burst of energy release involving accelerated particles. Methods: Instantaneous time-dependent charge states of silicon and oxygen were calculated and used to synthesize the instantaneous and period-averaged spectra of Si IV and O IV. Results: The electron beam drives the plasma out of equilibrium. At electron densities of Ne = 1010 cm-3, the plasma is out of ionization equilibrium at all times in all cases we considered, while for a higher density of Ne = 1011 cm-3, ionization equilibrium can be reached toward the end of each period, depending on the conditions. In turn, the character of the period-averaged synthetic spectra also depends on the properties of the beam. While the case of κ = 2 results in spectra with strong or even dominant O IV, higher values of κ can approximate a range of observed TR spectra. Spectra similar to typically observed spectra, with the Si IV 1402.8 Å line about a factor 5 higher than O IV 1401.2 Å, are obtained for κ = 3. An even higher value of κ = 5 results in spectra that are exclusively dominated by Si IV, with negligible O IV emission. This is a possible interpretation of the TR spectra of UV (Ellerman) bursts, although an interpretation that requires a density that is 1-3 orders of magnitude lower than for equilibrium estimates. Movies associated to Fig. A.1 are available at http://https://www.aanda.org

Commuting periodic operators and the periodic Wigner function

International Nuclear Information System (INIS)

Zak, J

2004-01-01

Commuting periodic operators (CPO) depending on the coordinate x-hat and the momentum p-hat operators are defined. The CPO are functions of the two basic commuting operators exp(i x-hat 2π/a) and exp(i/h p-hat a), with a being an arbitrary constant. A periodic Wigner function (PWF) w(x, p) is defined and it is shown that it is applicable in a normal expectation value calculation to the CPO, as done in the original Wigner paper. Moreover, this PWF is non-negative everywhere, and it can therefore be interpreted as an actual probability distribution. The PWF w(x, p) is shown to be given as an expectation value of the periodic Dirac delta function in the phase plane. (letter to the editor)

Amenorrhea - primary

Science.gov (United States)

... of periods - primary Images Primary amenorrhea Normal uterine anatomy (cut section) Absence of menstruation (amenorrhea) References Bulun SE. The physiology and pathology of the female reproductive axis. In: ...

Evaluation of the Usefulness of Restricted Respiratory Period at the Time of Radiotherapy for Non-Small Cell Lung Cancer Patient

Energy Technology Data Exchange (ETDEWEB)

Park, So Yeon; Ahn, Jong Ho; Kim, Yung Il; Kim, Jin Man; Choi, Byung Ki; Pyo, Hong Ryul; Song, Ki Won [Dept. of Radiation Oncology, Samsung Medical Center, Seoul (Korea, Republic of); Suh, Jung Min [Dept. of Radiological Science, Daewon University Colloge, Jecheon (Korea, Republic of)

2012-09-15

It is essential to minimize the movement of tumor due to respiratory movement at the time of respiration controlled radiotherapy of non-small cell lung cancer patient. Accordingly, this Study aims to evaluate the usefulness of restricted respiratory period by comparing and analyzing the treatment plans that apply free and restricted respiration period respectively. After having conducted training on 9 non-small cell lung cancer patients (tumor n=10) from April to December 2011 by using 'signal monitored-breathing (guided- breathing)' method for the 'free respiratory period' measured on the basis of the regular respiratory period of the patents and 'restricted respiratory period' that was intentionally reduced, total of 10 CT images for each of the respiration phases were acquired by carrying out 4D CT for treatment planning purpose by using RPM and 4-dimensional computed tomography simulator. Visual gross tumor volume (GTV) and internal target volume (ITV) that each of the observer 1 and observer 2 has set were measured and compared on the CT image of each respiratory interval. Moreover, the amplitude of movement of tumor was measured by measuring the center of mass (COM) at the phase of 0% which is the end-inspiration (EI) and at the phase of 50% which is the end-exhalation (EE). In addition, both observers established treatment plan that applied the 2 respiratory periods, and mean dose to normal lung (MDTNL) was compared and analyzed through dose-volume histogram (DVH). Moreover, normal tissue complication probability (NTCP) of the normal lung volume was compared by using dose-volume histogram analysis program (DVH analyzer v.1) and statistical analysis was performed in order to carry out quantitative evaluation of the measured data. As the result of the analysis of the treatment plan that applied the 'restricted respiratory period' of the observer 1 and observer 2, there was reduction rate of 38.75% in the 3-dimensional

Evaluation of the Usefulness of Restricted Respiratory Period at the Time of Radiotherapy for Non-Small Cell Lung Cancer Patient

International Nuclear Information System (INIS)

Park, So Yeon; Ahn, Jong Ho; Kim, Yung Il; Kim, Jin Man; Choi, Byung Ki; Pyo, Hong Ryul; Song, Ki Won; Suh, Jung Min

2012-01-01

It is essential to minimize the movement of tumor due to respiratory movement at the time of respiration controlled radiotherapy of non-small cell lung cancer patient. Accordingly, this Study aims to evaluate the usefulness of restricted respiratory period by comparing and analyzing the treatment plans that apply free and restricted respiration period respectively. After having conducted training on 9 non-small cell lung cancer patients (tumor n=10) from April to December 2011 by using 'signal monitored-breathing (guided- breathing)' method for the 'free respiratory period' measured on the basis of the regular respiratory period of the patents and 'restricted respiratory period' that was intentionally reduced, total of 10 CT images for each of the respiration phases were acquired by carrying out 4D CT for treatment planning purpose by using RPM and 4-dimensional computed tomography simulator. Visual gross tumor volume (GTV) and internal target volume (ITV) that each of the observer 1 and observer 2 has set were measured and compared on the CT image of each respiratory interval. Moreover, the amplitude of movement of tumor was measured by measuring the center of mass (COM) at the phase of 0% which is the end-inspiration (EI) and at the phase of 50% which is the end-exhalation (EE). In addition, both observers established treatment plan that applied the 2 respiratory periods, and mean dose to normal lung (MDTNL) was compared and analyzed through dose-volume histogram (DVH). Moreover, normal tissue complication probability (NTCP) of the normal lung volume was compared by using dose-volume histogram analysis program (DVH analyzer v.1) and statistical analysis was performed in order to carry out quantitative evaluation of the measured data. As the result of the analysis of the treatment plan that applied the 'restricted respiratory period' of the observer 1 and observer 2, there was reduction rate of 38.75% in the 3-dimensional direction movement of the tumor in

Menstruation and the Cycle of Poverty: A Cluster Quasi-Randomised Control Trial of Sanitary Pad and Puberty Education Provision in Uganda.

Science.gov (United States)

Montgomery, Paul; Hennegan, Julie; Dolan, Catherine; Wu, Maryalice; Steinfield, Laurel; Scott, Linda

2016-01-01

Poor menstrual knowledge and access to sanitary products have been proposed as barriers to menstrual health and school attendance. In response, interventions targeting these needs have seen increasing implementation in public and private sectors. However, there has been limited assessment of their effectiveness. Assess the impact of providing reusable sanitary pads and puberty education on girls' school attendance and psychosocial wellbeing outcomes. A cluster quasi-randomised controlled trial was conducted across 8 schools, including 1124 girls, in rural Uganda. Schools were allocated to one of four conditions: the provision of puberty education alone; reusable sanitary pads alone; puberty education and reusable sanitary pads; and a control (no intervention). The primary outcome was school attendance. Secondary outcomes reflected psychosocial wellbeing. At follow-up, school attendance had worsened for girls across all conditions. Per-protocol analysis revealed that this decline was significantly greater for those in the control condition d = 0.52 (95%CI 0.26-0.77), with those in control schools having a 17.1% (95%CI: 8.7-25.5) greater drop in attendance than those in any intervention school. There were no differences between the intervention conditions. High rates of school drop-out and transfer meant the trial suffered from substantial participant drop-out. Intention-to-treat analyses using two different imputation strategies were consistent with the main results, with mean differences of 5.2% attendance in best-case and 24.5% in worst-case imputations. Results were robust to adjustments for clustering. There was no impact of the interventions on girls' self-reported shame or insecurity during menstruation. Results of the trial support the hypothesised positive impact of providing sanitary pads or puberty education for girls' school attendance in a developing country context. Findings must be interpreted with caution in light of poor participant retention

Menstruation and the Cycle of Poverty: A Cluster Quasi-Randomised Control Trial of Sanitary Pad and Puberty Education Provision in Uganda.

Directory of Open Access Journals (Sweden)

Paul Montgomery

Full Text Available Poor menstrual knowledge and access to sanitary products have been proposed as barriers to menstrual health and school attendance. In response, interventions targeting these needs have seen increasing implementation in public and private sectors. However, there has been limited assessment of their effectiveness.Assess the impact of providing reusable sanitary pads and puberty education on girls' school attendance and psychosocial wellbeing outcomes.A cluster quasi-randomised controlled trial was conducted across 8 schools, including 1124 girls, in rural Uganda. Schools were allocated to one of four conditions: the provision of puberty education alone; reusable sanitary pads alone; puberty education and reusable sanitary pads; and a control (no intervention. The primary outcome was school attendance. Secondary outcomes reflected psychosocial wellbeing.At follow-up, school attendance had worsened for girls across all conditions. Per-protocol analysis revealed that this decline was significantly greater for those in the control condition d = 0.52 (95%CI 0.26-0.77, with those in control schools having a 17.1% (95%CI: 8.7-25.5 greater drop in attendance than those in any intervention school. There were no differences between the intervention conditions. High rates of school drop-out and transfer meant the trial suffered from substantial participant drop-out. Intention-to-treat analyses using two different imputation strategies were consistent with the main results, with mean differences of 5.2% attendance in best-case and 24.5% in worst-case imputations. Results were robust to adjustments for clustering. There was no impact of the interventions on girls' self-reported shame or insecurity during menstruation.Results of the trial support the hypothesised positive impact of providing sanitary pads or puberty education for girls' school attendance in a developing country context. Findings must be interpreted with caution in light of poor participant

Menstruation and the Cycle of Poverty: A Cluster Quasi-Randomised Control Trial of Sanitary Pad and Puberty Education Provision in Uganda

Science.gov (United States)

Montgomery, Paul; Hennegan, Julie; Dolan, Catherine; Wu, Maryalice; Steinfield, Laurel; Scott, Linda

2016-01-01

Background Poor menstrual knowledge and access to sanitary products have been proposed as barriers to menstrual health and school attendance. In response, interventions targeting these needs have seen increasing implementation in public and private sectors. However, there has been limited assessment of their effectiveness. Objectives Assess the impact of providing reusable sanitary pads and puberty education on girls’ school attendance and psychosocial wellbeing outcomes. Methods A cluster quasi-randomised controlled trial was conducted across 8 schools, including 1124 girls, in rural Uganda. Schools were allocated to one of four conditions: the provision of puberty education alone; reusable sanitary pads alone; puberty education and reusable sanitary pads; and a control (no intervention). The primary outcome was school attendance. Secondary outcomes reflected psychosocial wellbeing. Results At follow-up, school attendance had worsened for girls across all conditions. Per-protocol analysis revealed that this decline was significantly greater for those in the control condition d = 0.52 (95%CI 0.26–0.77), with those in control schools having a 17.1% (95%CI: 8.7–25.5) greater drop in attendance than those in any intervention school. There were no differences between the intervention conditions. High rates of school drop-out and transfer meant the trial suffered from substantial participant drop-out. Intention-to-treat analyses using two different imputation strategies were consistent with the main results, with mean differences of 5.2% attendance in best-case and 24.5% in worst-case imputations. Results were robust to adjustments for clustering. There was no impact of the interventions on girls’ self-reported shame or insecurity during menstruation. Conclusion Results of the trial support the hypothesised positive impact of providing sanitary pads or puberty education for girls’ school attendance in a developing country context. Findings must be interpreted

Quality assurance in road traffic analyses in Switzerland.

Science.gov (United States)

Briellmann, Thomas A; Sigrist, Thomas; Augsburger, Marc; Favrat, Bernard; Oestreich, Andrea; Deom, André

2010-05-20

Swiss laboratories performing toxicological road traffic analyses have been authorized for many years by the Swiss Federal Roads Office (FEDRO). In 2003 FEDRO signed a contract with the Swiss Society of Legal Medicine (SSLM) to organize the complete quality management concerning road traffic analyses. For this purpose a multidisciplinary working group was established under the name of "road traffic commission (RTC)". RTC has to organize external quality control, to interpret the results of these controls, to perform audits in the laboratories and to report all results to FEDRO. Furthermore the working group can be mandated for special tasks by FEDRO. As an independent organization the Swiss Center for Quality Control (CSCQ) in Geneva manages the external quality controls in the laboratory over the past years. All tested drugs and psychoactive substances are listed in a federal instruction. The so-called 'zero tolerance substances' (THC, morphine, cocaine, amphetamine, methamphetamine, MDMA and MDEA) and their metabolites have to be tested once a year, all other substances (benzodiazepines, zolpidem, phenobarbital, etc.) periodically. Results over the last years show that all laboratories are generally within the confidence interval of +/-30% of the mean value. In cases of non-conformities measures have to be taken immediately and reported to the working group. External audits are performed triennially but accredited laboratories can combine this audit with the approval of the Swiss Accreditation Service (SAS). During the audits a special checklist filled in by the laboratory director is assessed. Non-conformities have to be corrected. During the process of establishing a new legislation, RTC had an opportunity of advising FEDRO. In collaboration with FEDRO, RTC and hence SSLM can work actively on improving of quality assurance in road traffic toxicological analyses, and has an opportunity to bring its professional requests to the federal authorities.

Influence of blood glucose level, age and fasting period on non-pathological FDG uptake in heart and gut

International Nuclear Information System (INIS)

Groot, Michel de; Meeuwis, Antoi P.W.; Kok, Peter J.M.; Corstens, Frans H.M.; Oyen, Wim J.G.

2005-01-01

Increased, non-pathological FDG uptake in myocardium, stomach and bowel is frequently observed while performing clinical positron emission tomography (PET) studies. This ''physiological'' increased FDG uptake is not related to (oncological) disease and is unwanted since it may interfere with correct image reading. We evaluated the role of several patient-related factors that may have an influence on this phenomenon. One hundred and seventy-five non-diabetic patients with malignant diseases, referred to our department for routine whole-body FDG-PET, were retrospectively evaluated. Age, blood glucose levels and duration of the fasting period were recorded. FDG uptake in myocardium, bowel and stomach was visually graded. Statistical analysis showed that increased FDG uptake in myocardium, bowel and stomach was not significantly correlated to blood glucose level, age or duration of fasting. Most patients who underwent repeated PET scans (92 scans in 25 patients), showed no or minor changes in uptake in bowel and stomach on the consecutive scans, while myocardial uptake was more variable. Age, fasting period and blood glucose levels did not influence physiological uptake. However, there seemed to be a patient-specific pattern for stomach and bowel uptake. (orig.)

Stability of personality traits over a five-year period in Swedish patients with schizophrenia spectrum disorder and non-psychotic individuals: a study using the Swedish universities scales of personality.

Science.gov (United States)

Fagerberg, Tomas; Söderman, Erik; Petter Gustavsson, J; Agartz, Ingrid; Jönsson, Erik G

2018-02-27

Personality is considered as an important aspect in persons with psychotic disorders. Several studies have investigated personality in schizophrenia. However, no study has investigated stability of personality traits exceeding three years in patients with schizophrenia. This study aims to investigate the stability of personality traits over a five-year period among patients with schizophrenia and non-psychotic individuals and to evaluate case-control differences. Patients with psychotic disorders (n = 36) and non-psychotic individuals (n = 76) completed Swedish universities Scales of Personality (SSP) at two occasions five years apart. SSP scores were analysed for effect of time and case-control differences by multiple analysis of covariance (MANCOVA) and within-subjects correlation. MANCOVA within-subjects analysis did not show any effect of time. Thus, SSP mean scale scores did not significantly vary during the five-year interval. Within subject correlations (Spearman) ranged 0.30-0.68 and 0.54-0.75 for the different SSP scales in patients and controls, respectively. Patients scored higher than controls in SSP scales Somatic Trait Anxiety, Psychic Trait Anxiety, Stress Susceptibility, Lack of Assertiveness, Detachment, Embitterment, and Mistrust. The stability of the SSP personality trait was reasonably high among patients with psychotic disorder, although lower than among non-psychotic individuals, which is in accordance with previous research.

Magnetic resonance imaging of morphological and functional changes of the uterus induced by sacral surface electrical stimulation

International Nuclear Information System (INIS)

Ogura, Takahide; Murakami, Takashi; Ozawa, Yuka; Seki, Kazunori; Handa, Yasunobu

2006-01-01

The purpose of this study is to examine the morphological and kinematical changes of the uterus induced by electrical stimulation applied to the skin just above the second and fourth posterior sacral foramens (sacral surface electrical stimulation [ssES]) in 26 healthy subjects. Out of them, eight subjects who had severe pain subjectively during every menstruation received ssES just in menstruation. Morphological and functional changes of the uterus were examined by using T2-weighted magnetic resonance (MR) imaging and T1-weighted MR cinematography, respectively. Cyclic electrical stimulation for 15 min with 5 sec ON and 5 sec OFF was applied just before MR scanning. A decrease in thickness of the muscular layer of the uterus was observed in every subject after ssES for 15 min and was significant as compared with the thickness before ssES. Periodic uterine movement during menstruation was observed in the subjects with severe menstrual pain in MR cine and the power spectrum analysis of the movement showed a marked decrease in peak power and frequency after ssES treatment. We conclude that ssES causes a reduction of static muscle tension of the uterus in all menstrual cycle periods and suppression of uterine peristalsis during menstruation in the subjects with severe menstrual pain. Possible neural mechanisms for these static and dynamic effects of ssES on the uterus at spinal level are discussed. (author)

The Non-Fiction Reading Habits of Young Successful Boy Readers: Forming Connections between Masculinity and Reading

Science.gov (United States)

Smith, Susannah

2004-01-01

The reading experiences of six young successful boy readers were studied over a two-year period. In this article, their non-fiction reading is analysed and ways in which the boys make positive connections between masculinity and reading are identified. The boys' non-fiction reading centres on typical boy interest areas and hobbies (for example,…

Attitudes toward menstruation, menstrual-related symptoms, and premenstrual syndrome among adolescent girls: a rural school-based survey.

Science.gov (United States)

Wong, Li Ping

2011-06-21

Folk culture surrounding menstrual-related matters has considerable implications for symptom expression and treatment-seeking behavior. A cross-sectional survey of 1,295 rural adolescent girls aged 13 to 19 years was conducted between February 4 and April 16, 2009 to examine these associations. With a higher score indicating a more positive attitude toward menstruation, the mean attitude score was 3.84 (SD ± 1.62) out of a maximum of six. No significant association was observed between the severity of menstrual symptoms and attitudes. Most (63.1%) of the participants identified themselves as having premenstrual symptoms, and 61.1% viewed premenstrual symptoms as a normal part of menstrual cycle. Participants with a higher severity of symptoms in the premenstrual (OR 1.05, 95% CI 1.01-1.10) and menstrual phase (OR 1.04, 95% CI 1.01-1.07), were more likely to consult a physician for premenstrual symptoms, and having a divorced/separated parents was associated with a reduced odds of consulting a physician compared to those having parents that were married (OR 0.19, 95% CI 0.05-0.83). The findings imply the need for education to help adolescent girls manage menstrual symptoms and increase awareness of the benefit of treating them. Given that menstrual-related information was widely available from mothers, family, and social culture are potentially important in shaping good menstrual attitudes.

Emergency Diesel Generation System Surveillance Test Policy Optimization Through Genetic Algorithms Using Non-Periodic Intervention Frequencies and Seasonal Constraints

International Nuclear Information System (INIS)

Lapa, Celso M.F.; Pereira, Claudio M.N.A.; Frutuoso e Melo, P.F.

2002-01-01

Nuclear standby safety systems must frequently, be submitted to periodic surveillance tests. The main reason is to detect, as soon as possible, the occurrence of unrevealed failure states. Such interventions may, however, affect the overall system availability due to component outages. Besides, as the components are demanded, deterioration by aging may occur, penalizing again the system performance. By these reasons, planning a good surveillance test policy implies in a trade-off between gains and overheads due to the surveillance test interventions. In order maximize the systems average availability during a given period of time, it has recently been developed a non-periodic surveillance test optimization methodology based on genetic algorithms (GA). The fact of allowing non-periodic tests turns the solution space much more flexible and schedules can be better adjusted, providing gains in the overall system average availability, when compared to those obtained by an optimized periodic tests scheme. The optimization problem becomes, however, more complex. Hence, the use of a powerful optimization technique, such as GAs, is required. Some particular features of certain systems can turn it advisable to introduce other specific constraints in the optimization problem. The Emergency Diesel Generation System (EDGS) of a Nuclear Power Plant (N-PP) is a good example for demonstrating the introduction of seasonal constraints in the optimization problem. This system is responsible for power supply during an external blackout. Therefore, it is desirable during periods of high blackout probability to maintain the system availability as high as possible. Previous applications have demonstrated the robustness and effectiveness of the methodology. However, no seasonal constraints have ever been imposed. This work aims at investigating the application of such methodology in the Angra-II Brazilian NPP EDGS surveillance test policy optimization, considering the blackout probability

Association between menarche and iron deficiency in non-anemic young women.

Directory of Open Access Journals (Sweden)

Deepa L Sekhar

Full Text Available The prevalence of iron deficiency (ID among non-pregnant, reproductive-age US women significantly exceeds rates among males. In clinical practice ID screening relies on hemoglobin, a late-stage indicator of ID. As a single, low-cost laboratory test to diagnose ID before anemia develops is lacking, the study objective was to improve ID screening by identifying risk factors among non-anemic, iron-deficient reproductive age women.Cross-sectional data were from the National Health and Nutrition Examination Survey (NHANES 2003-2010. Hemoglobin identified non-anemic women. ID was defined using the body iron formula, requiring ferritin and transferrin receptor values. Logistic regression assessed the association of sociodemographic, behavioral, and reproductive risk factors in an anemia-based conceptual framework with non-anemic reproductive age women (12-49 years with ID, as well as subsets of younger (12-21 years and older (22-49 years women, recognizing that risks may differ by age.Among 6216 women, 494 had ID (prevalence was 8.0%, 95% CI 7.3%, 8.6%. Among non-anemic younger women, 250 (8.7%, 95% CI 7.7%, 9.8% had ID, compared to 244 (7.3%, 95% CI 6.4%, 8.2% older women. Among younger women, menstruation for over 3 years was the only variable significantly associated with non-anemic ID (risk ratio 3.18, 95% CI 2.03, 4.96. No other significant risk factors were identified.Menstrual years was the only risk factor significantly associated with ID among non-anemic younger women. The negative results suggest ID risk factors among non-anemic women may need to be considered separately from those associated with ID anemia.

Non-equilibrium ionization by a periodic electron beam. I. Synthetic coronal spectra and implications for interpretation of observations

Science.gov (United States)

Dzifčáková, E.; Dudík, J.; Mackovjak, Š.

2016-05-01

Context. Coronal heating is currently thought to proceed via the mechanism of nanoflares, small-scale and possibly recurring heating events that release magnetic energy. Aims: We investigate the effects of a periodic high-energy electron beam on the synthetic spectra of coronal Fe ions. Methods: Initially, the coronal plasma is assumed to be Maxwellian with a temperature of 1 MK. The high-energy beam, described by a κ-distribution, is then switched on every period P for the duration of P/ 2. The periods are on the order of several tens of seconds, similar to exposure times or cadences of space-borne spectrometers. Ionization, recombination, and excitation rates for the respective distributions are used to calculate the resulting non-equilibrium ionization state of Fe and the instantaneous and period-averaged synthetic spectra. Results: Under the presence of the periodic electron beam, the plasma is out of ionization equilibrium at all times. The resulting spectra averaged over one period are almost always multithermal if interpreted in terms of ionization equilibrium for either a Maxwellian or a κ-distribution. Exceptions occur, however; the EM-loci curves appear to have a nearly isothermal crossing-point for some values of κs. The instantaneous spectra show fast changes in intensities of some lines, especially those formed outside of the peak of the respective EM(T) distributions if the ionization equilibrium is assumed. Movies 1-5 are available in electronic form at http://www.aanda.org

[Natural progression of premature pubarche and underlying diseases].

Science.gov (United States)

Sancho Rodríguez, María Luisa; Bueno Lozano, Gloria; Labarta Aizpún, José Ignacio; de Arriba Muñoz, Antonio

2018-04-25

Premature pubarche (PP) is generally thought to be a benign condition, but it can also be the first sign of underlying disease. To analyse the aetiology and the evolution of the anthropometric, analytical and metabolic risk parameters of a group of patients with PP. A descriptive and analytical retrospective study of 92 patients affected by PP. Anthropometry, analyses, bone age and indicators of lipid metabolism were all evaluated. The sample included 92 patients with PP (67 female and 25 male), with a mean age of 7.1±0.6 for girls and 8.3±0.7 for boys. Small for gestational age was recorded in 7.7%. There was an accelerated bone age (1.20±0.1 years). A total of 21 patients were classified as idiopathic (23%), 60 as idiopathic premature adrenarche (65%), and 11 with non-classic congenital adrenal hyperplasia (12%). Puberty was reached early (11+0.9 years old in boys and 9.9±0.8 in girls), as was menstruation age (11.8+1.1 years old), P<.001. The stature finally reached was close to their genetic stature. There is a positive correlation between body mass index, blood glucose and LDL cholesterol, as well as a tendency towards hyperinsulinaemia. The present study shows that PP is a benign condition in the majority of cases, but non-classic congenital adrenal hyperplasia (12%) is not uncommon. Menstruation and puberty started early and bone age was accelerated. Growth was normal, and more or less in line with genetic size. PP associated with obesity is linked with analytical variations of metabolic risks. Copyright © 2017. Publicado por Elsevier España, S.L.U.

Uncertainty and sensitivity analyses of ballast life-cycle cost and payback period

OpenAIRE

Mcmahon, James E.

2000-01-01

The paper introduces an innovative methology for evaluating the relative significance of energy-efficient technologies applied to fluorescent lamp ballasts. The method involves replacing the point estimates of life cycle cost of the ballasts with uncertainty distributions reflecting the whole spectrum of possible costs, and the assessed probability associated with each value. The results of uncertainty and sensitivity analyses will help analysts reduce effort in data collection and carry on a...

Interpretations of Frequency Domain Analyses of Neural Entrainment: Periodicity, Fundamental Frequency, and Harmonics.

Science.gov (United States)

Zhou, Hong; Melloni, Lucia; Poeppel, David; Ding, Nai

2016-01-01

Brain activity can follow the rhythms of dynamic sensory stimuli, such as speech and music, a phenomenon called neural entrainment. It has been hypothesized that low-frequency neural entrainment in the neural delta and theta bands provides a potential mechanism to represent and integrate temporal information. Low-frequency neural entrainment is often studied using periodically changing stimuli and is analyzed in the frequency domain using the Fourier analysis. The Fourier analysis decomposes a periodic signal into harmonically related sinusoids. However, it is not intuitive how these harmonically related components are related to the response waveform. Here, we explain the interpretation of response harmonics, with a special focus on very low-frequency neural entrainment near 1 Hz. It is illustrated why neural responses repeating at f Hz do not necessarily generate any neural response at f Hz in the Fourier spectrum. A strong neural response at f Hz indicates that the time scales of the neural response waveform within each cycle match the time scales of the stimulus rhythm. Therefore, neural entrainment at very low frequency implies not only that the neural response repeats at f Hz but also that each period of the neural response is a slow wave matching the time scale of a f Hz sinusoid.

Statistical Survey of Non-Formal Education

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Ondřej Nývlt

2012-12-01

Full Text Available focused on a programme within a regular education system. Labour market flexibility and new requirements on employees create a new domain of education called non-formal education. Is there a reliable statistical source with a good methodological definition for the Czech Republic? Labour Force Survey (LFS has been the basic statistical source for time comparison of non-formal education for the last ten years. Furthermore, a special Adult Education Survey (AES in 2011 was focused on individual components of non-formal education in a detailed way. In general, the goal of the EU is to use data from both internationally comparable surveys for analyses of the particular fields of lifelong learning in the way, that annual LFS data could be enlarged by detailed information from AES in five years periods. This article describes reliability of statistical data aboutnon-formal education. This analysis is usually connected with sampling and non-sampling errors.

NPP Krsko periodic safety review. Safety assessment and analyses

International Nuclear Information System (INIS)

Basic, I.; Spiler, J.; Thaulez, F.

2002-01-01

Definition of a PSR (Periodic Safety Review) project is a comprehensive safety review of a plant after ten years of operation. The objective is a verification by means of a comprehensive review using current methods that the plant remains safe when judged against current safety objectives and practices and that adequate arrangements are in place to maintain plant safety. The overall goals of the NEK PSR Program are defined in compliance with the basic role of a PSR and the current practice typical for most of the countries in EU. This practice is described in the related guides and good practice documents issued by international organizations. The overall goals of the NEK PSR are formulated as follows: to demonstrate that the plant is as safe as originally intended; to evaluate the actual plant status with respect to aging and wear-out identifying any structures, systems or components that could limit the life of the plant in the foreseeable future, and to identify appropriate corrective actions, where needed; to compare current level of safety in the light of modern standards and knowledge, and to identify where improvements would be beneficial for minimizing deviations at justifiable costs. The Krsko PSR will address the following safety factors: Operational Experience, Safety Assessment, EQ and Aging Management, Safety Culture, Emergency Planning, Environmental Impact and Radioactive Waste.(author)

Menstrual knowledge and practices of female adolescents in Vhembe district, Limpopo Province, South Africa.

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Ramathuba, Dorah U

2015-11-26

Although sexual issues are openly discussed in the media, sexuality and reproductive functions are treated as taboo. Menstruation is a normal physiologic process, but carries various meanings within cultures and is rarely discussed amongst families and communities. This study sought to assess the knowledge and practices of secondary school girls towards menstruation in the Thulamela municipality of Limpopo Province, South Africa. A quantitative descriptive study design was used and respondents were selected by means of convenience sampling from a population of secondary school girls. The sample consisted of 273 secondary school girls doing Grades 10-12. A self-administered questionnaire was used to collect data, which was analysed by computing frequencies and percentages using the Statistical Package for Social Sciences (SPSS version 12). The findings revealed that respondents experienced menarche at 13 years and that menstruation is a monthly bleeding (80%) that happens to every female; it is a sign of adulthood (91%). 15% reported that it is the removal of dirt from the stomach and abdomen, 67% indicated the source of menstruation being the uterus, 65% the vagina and 13% from the abdomen. 73% reported having fear and anxiety at the first experience of bleeding and that they could not maintain adequate hygienic practices due to a lack of privacy and sanitary towels. Interventions are needed to increase girls' opportunities to discuss menstruation and access information from adults including mothers, parents and guardians. School-based sexuality education should be comprehensive, begin early and be regularly repeated.

Comparative biochemical analyses of venous blood and peritoneal fluid from horses with colic using a portable analyser and an in-house analyser.

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Saulez, M N; Cebra, C K; Dailey, M

2005-08-20

Fifty-six horses with colic were examined over a period of three months. The concentrations of glucose, lactate, sodium, potassium and chloride, and the pH of samples of blood and peritoneal fluid, were determined with a portable clinical analyser and with an in-house analyser and the results were compared. Compared with the in-house analyser, the portable analyser gave higher pH values for blood and peritoneal fluid with greater variability in the alkaline range, and lower pH values in the acidic range, lower concentrations of glucose in the range below 8.3 mmol/l, and lower concentrations of lactate in venous blood in the range below 5 mmol/l and in peritoneal fluid in the range below 2 mmol/l, with less variability. On average, the portable analyser underestimated the concentrations of lactate and glucose in peritoneal fluid in comparison with the in-house analyser. Its measurements of the concentrations of sodium and chloride in peritoneal fluid had a higher bias and were more variable than the measurements in venous blood, and its measurements of potassium in venous blood and peritoneal fluid had a smaller bias and less variability than the measurements made with the in-house analyser.

Menstrual hygiene management and school absenteeism among female adolescent students in Northeast Ethiopia.

Science.gov (United States)

Tegegne, Teketo Kassaw; Sisay, Mitike Molla

2014-10-29

Adolescence in girls has been recognized as a special period marked with the onset of menarche. Even though menstruation is a natural process, it is associated with misconceptions, malpractices and challenges among girls in developing countries. However, much is not documented; school-absenteeism and dropout are a common problem among girls in rural Ethiopia. Focusing among school girls, this study has examined knowledge about menstruation, determinants of menstrual management and its influence on school-attendance in Northeast Ethiopia. We conducted a mixed-method research combining quantitative and qualitative methods in Northeast Ethiopia. The quantitative study was conducted among 595 randomly selected adolescent school girls. Nine in-depth interviews; five school-dropout girls and four female teachers, and four focus group discussions among school girls were conducted in 2013. The mean age at menarche was 13.98 (±1.17) years. About 51% of girls had knowledge about menstruation and its management. Only a third of the girls used sanitary napkins as menstrual absorbent during their last menstruation. Girls from urban areas, had mothers of secondary and above education and, families of higher monthly expenditure had more chance of using sanitary napkins than their counterparts. More than half of the girls reported to have been absent from school during their menstruation period. Those who did not use sanitary napkins were more likely to be absent from school [AOR-95% C.I: 5.37 (3.02 - 9.55)]. Fifty eight percent of girls reported that their school-performance had declined after they had menarche. In addition, the qualitative study indicated that school-dropout was common among girls who experienced teasing and humiliation by classmates when their clothes were stained with blood as they do not use sanitary napkins. Though there is an effort to increase girls' school enrollment, lack of basic needs, like sanitary napkins that facilitate routine activates of girls

SLAVIC LITERATURES IN DALMATIAN PERIODICALS IN THE PERIOD OF CROATIAN MODERNISM

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Robert Bacalja

2010-01-01

Full Text Available The paper analyzes translations and mediatorial articles from the Slavic literature published in Dalmatian newspapers and periodicals which contribute most to mediation during the period of Croatian Modernism. While periodicals in Dalmatia traditionally mediates from the Roman literature, especially from the Italian, in the examined corpus can be seen the remarkable reception of Slavic literature, particularly Russian.. The paradigm of the most recognized culture and literature in non Slavic world is desirable identity basis of the Croatian literature as a part of a large Slavic stem from romanticism to modernism. Mediation of Slavic literatures is examined on the corpus of newspapers and periodicals published in Dubrovnik, Split and Zadar (Crvena Hrvatska, Srđ, Sloboda, Jedinstvo/Novo jedinstvo, Novi vijek, Narodni list, Smotra dalmatinska, Iskra, Glasnik Matice dalmatinske, Lovor, etc..

Source mechanisms of persistent shallow earthquakes during eruptive and non-eruptive periods between 1981 and 2011 at Mount St. Helens, Washington

Science.gov (United States)

Lehto, Heather L.; Roman, Diana C.; Moran, Seth C.

2013-01-01

Shallow seismicity between 0 and 3-km depth has persisted at Mount St. Helens, Washington (MSH) during both eruptive and non-eruptive periods for at least the past thirty years. In this study we investigate the source mechanisms of shallow volcano-tectonic (VT) earthquakes at MSH by calculating high-quality hypocenter locations and fault plane solutions (FPS) for all VT events recorded during two eruptive periods (1981–1986 and 2004–2008) and two non-eruptive periods (1987–2004 and 2008–2011). FPS show a mixture of normal, reverse, and strike-slip faulting during all periods, with a sharp increase in strike-slip faulting observed in 1987–1997 and an increase in normal faulting in 1998–2004. FPS P-axis orientations show a ~ 90° rotation with respect to regional σ1 (N23°E) during 1981–1986 and 2004–2008, bimodal orientations (~ N-S and ~ E-W) during 1987–2004, and bimodal orientations at ~ N-E and ~ S-W from 2008–2011. We interpret these orientations to likely be due to pressurization accompanying the shallow intrusion and subsequent eruption of magma as domes during 1981–1986 and 2004–2008 and the buildup of pore pressure beneath a seismogenic volume (located at 0–1 km) with a smaller component due to the buildup of tectonic forces during 1987–2004 and 2008–2011.

IUE observations of long period eclipsing binaries: a study of accretion onto non-degenerate stars

International Nuclear Information System (INIS)

Plavec, M.J.

1980-01-01

It has long been thought that β Lyrae is a unique system, by virtue of its UV spectrum and its nature. The author argues that a whole class of interacting long-period binaries exists, similar to β Lyrae. According to IUE observations made in 1978-79 this group comprises: RX Cas, SX Cas, V 367 Cyg, W Cru, β Lyr, and W Ser. AR Pav is a transition case linking them with the symbiotics. The author also suggests that HD 218393 (KX And), HD 72754, and HD 51480 are their non-eclipsing counterparts. The whole group is called the W Serpentis stars. These systems are mass-transfering binaries (case B) in which the mass transfer rate is relatively high, probably on the order 10 -6 to 10 -4 solar masses/year. They display an ultraviolet continuum with a color temperature definitely higher than the one observed in the optical region. Even more characteristical is the presence of strong emission lines of N V, C IV, Si IV, Fe III, Al III, and lower ions of C and Si. The author discusses these phenomena on the assumption that they are due to accretion onto non-degenerate stars. (Auth.)

Cross-sectional associations between daily rest periods during weekdays and psychological distress, non-restorative sleep, fatigue, and work performance among information technology workers.

Science.gov (United States)

Tsuchiya, Masao; Takahashi, Masaya; Miki, Keiichi; Kubo, Tomohide; Izawa, Shuhei

2017-04-07

A daily rest period (DRP; rest taken from daily work during a 24 h period), is essential to work recovery. This study examined DRPs' distribution and association with health outcomes among information technology workers recruited from an internet panel (N=1,811). Participants completed a web questionnaire examining psychological distress as a primary outcome, along with non-restorative sleep, fatigue (stress reaction), and work performance. Logistic regression analysis showed elevated psychological distress when DRP was working and commuting hours. After the above adjustment, similar associations were found with non-restorative sleep and fatigue, but not work performance, when DRP was <12 h. These findings constitute the first analysis of a dose-response relationship between DRP and subjective health outcomes among white-collar workers.

Houdbaarheid en conservering van grondwatermonsters voor anorganische analyses

NARCIS (Netherlands)

Cleven RFMJ; Gast LFL; Boshuis-Hilverdink ME; LAC

1995-01-01

The storage life and the possibilities for preservation of inorganic analyses of groundwater samples have been investigated. Groundwater samples, with and without preservation with acid, from four locations in the Netherlands have been analysed ten times over a period of three months on six

Relationship between motion sickness, migraine and menstruation in crew members of a "round the world" yacht race.

Science.gov (United States)

Grunfeld, E; Gresty, M A

1998-11-15

The similarities between the symptoms reported by patients with migraine and those experienced by severely motion sick individuals raises the question of whether the two conditions involve common mechanisms. In women, attacks of migraine may follow the menstrual cycle, and anecdote suggests this may also be true of motion sickness. The aim of this study was to determine whether there was a cyclical pattern in the occurrence of migraine/headache and motion sickness among crew members of a "round the world" yacht race. The participants were asked to complete pre- and postrace questionnaires that related to their susceptibility to motion sickness and headache/migraine; additionally, the female subjects were asked for details about their menstrual cycle. During the race the subjects completed a logbook to record the occurrence of motion sickness (using a four-point scale), migraine/headache (including the type of headache), menstruation, medication consumption and duties aboard the yacht. Female sailors were found to be more prone to motion sickness than the males. Motion sickness was also found to be linked to time at sea, and subjects who suffered migraine during the race were also more susceptible to motion sickness. A distinct pattern was found in the occurrence of motion sickness and headache that related to the menstrual cycle, although motion sickness and headache did not generally occur together in most of the subjects. A cyclical pattern was not obvious for the male subjects.

A data mining approach: Analyzing wind speed and insolation period data in Turkey for installations of wind and solar power plants

International Nuclear Information System (INIS)

Colak, Ilhami; Sagiroglu, Seref; Demirtas, Mehmet; Yesilbudak, Mehmet

2013-01-01

Highlights: ► Wind speed and insolation period data were analyzed using a data mining approach. ► Most of the studies in the literature were based on Weibull and Rayleigh models. ► Nearest and farest neighbor algorithms were used with different distance metrics. ► Many inferences were achieved in efficient limits for wind and solar farm analyses. - Abstract: Wind and solar power plant installations have been recently increased rapidly with respect to the depletion of fossil-based fuels all over the world. Due to stochastic nature of meteorological conditions, wind and solar energies have a non-schedulable nature and they require several installation analyses to determine the location and the capacities of wind and solar power to be produced. This paper focuses on the similarity, feasibility and numerical analyses of 75 cities in Turkey based on the monthly average wind speed and insolation period data. The nearest and the farest neighbor algorithms are used as agglomerative hierarchical clustering methods with Euclidean, Manhattan and Minkowski distance metrics in the stage of making the similarity and feasibility analyses. The maximum cophenetic correlation coefficient is achieved by the nearest neighbor algorithm with the Minkowski distance metric in the similarity and feasibility analyses. On the other hand, graphical representations of the monthly average wind speed and insolation period data are utilized for making the numerical analysis. The highest annual average wind speed and insolation period are obtained as 3.88 m/s and 8.45 h/day, respectively. Overall, many inferences were achieved in acceptable and efficient limits for wind and solar energy.

Genetics Home Reference: Perrault syndrome

Science.gov (United States)

... Severely affected girls do not begin menstruation by age 16 (primary amenorrhea), and most never have a menstrual period. Less severely affected women have an early loss of ovarian function (primary ovarian insufficiency); their ...

Genetics Home Reference: Gilbert syndrome

Science.gov (United States)

... instance because of dehydration, prolonged periods without food (fasting), illness, vigorous exercise, or menstruation. Some people with ... to conjugated bilirubin. Glucuronidation makes bilirubin dissolvable in water so that it can be removed from the ...

Atomic adsorption on pristine graphene along the Periodic Table of Elements - From PBE to non-local functionals

Science.gov (United States)

Pašti, Igor A.; Jovanović, Aleksandar; Dobrota, Ana S.; Mentus, Slavko V.; Johansson, Börje; Skorodumova, Natalia V.

2018-04-01

The understanding of atomic adsorption on graphene is of high importance for many advanced technologies. Here we present a complete database of the atomic adsorption energies for the elements of the Periodic Table up to the atomic number 86 (excluding lanthanides) on pristine graphene. The energies have been calculated using the projector augmented wave (PAW) method with PBE, long-range dispersion interaction corrected PBE (PBE+D2, PBE+D3) as well as non-local vdW-DF2 approach. The inclusion of dispersion interactions leads to an exothermic adsorption for all the investigated elements. Dispersion interactions are found to be of particular importance for the adsorption of low atomic weight earth alkaline metals, coinage and s-metals (11th and 12th groups), high atomic weight p-elements and noble gases. We discuss the observed adsorption trends along the groups and rows of the Periodic Table as well some computational aspects of modelling atomic adsorption on graphene.

Effects of Environment in the Microstructure and Properties of Sustainable Mortars with Fly Ash and Slag after a 5-Year Exposure Period

Directory of Open Access Journals (Sweden)

José Marcos Ortega

2018-03-01

Full Text Available Nowadays, getting a more environmentally sustainable cement production is one of the main goals of the cement industry. In this regard, the use of active additions, like fly ash and ground granulated blast-furnace slag, has become very popular. The behaviour, in the short-term, of cement-based materials with those additions is well-known when their hardening is produced under optimum conditions. However, real structures are exposed to different environments during long periods, which could affect the development of microstructures and the service properties of cementitious materials. The objective of this work is to analyse the effects in the long-term (up to 5 years approximately produced by the exposure to different non-optimum laboratory conditions in the microstructure, mechanical and durability properties of mortars made with slag and fly ash commercial cements. Their performance was compared to that observed for ordinary Portland cement (OPC mortars. The microstructure has been analysed using mercury intrusion porosimetry. The effective porosity, the capillary suction coefficient, the chloride migration coefficient and mechanical strengths were analysed too. According to the results, mortars prepared using slag and fly ash sustainable commercial cements, exposed to non-optimum conditions, show a good performance after 5-years hardening period, similar or even better than OPC mortars.

The 'nonmenstrual woman' in the new millennium? Discourses on menstrual suppression in the first decade of extended cycle oral contraception use in Canada.

Science.gov (United States)

Granzow, Kara

2014-06-01

In the early-twenty-first century, extended cycle oral contraception (ECOC) became available by physician prescription in North America. Researchers speculate that this drug, with its capacity to reduce or eliminate menstrual bleeding, may shift not only women's biological processes but also their experiences of menstruation. In this paper, I discuss women's experiences of menstrual suppression drawing on findings from a qualitative study conducted before ECOC was available, and examine these findings against recently published research on menstrual suppression in an ECOC era. Findings suggest that the body as a natural entity figures strongly in women's discourses on suppression. They further suggest that suppression is a contingent, paradoxical and practical achievement, not a securely or fully realised embodied state. This paper reads women's accounts of menstrual suppression prior to ECOC as a challenge to the modern artifice of a mind/body split, and questions whether this challenge is perhaps made less discernible in an ECOC era, where attention may no longer be paid to the daily practices of menstrual suppression. Hence, a case is made for the varied political effects of ongoing non-menstruation versus event-specific practices of non-menstruation.

Assessing non-linear variation of temperature and precipitation for different growth periods of maize and their impacts on phenology in the Midwest of Jilin Province, China

Science.gov (United States)

Guo, Enliang; Zhang, Jiquan; Wang, Yongfang; Alu, Si; Wang, Rui; Li, Danjun; Ha, Si

2018-05-01

In the past two decades, the regional climate in China has undergone significant change, resulting in crop yield reduction and complete failure. The goal of this study is to detect the variation of temperature and precipitation for different growth periods of maize and assess their impact on phenology. The daily meteorological data in the Midwest of Jilin Province during 1960-2014 were used in the study. The ensemble empirical mode decomposition method was adopted to analyze the non-linear trend and fluctuation in temperature and precipitation, and the sensitivity of the length of the maize growth period to temperature and precipitation was analyzed by the wavelet cross-transformation method. The results show that the trends of temperature and precipitation change are non-linear for different growth periods of maize, and the average temperature in the sowing-jointing stage was different from that in the other growth stages, showing a slight decrease trend, while the variation amplitude of maximum temperature is smaller than that of the minimum temperature. This indicates that the temperature difference between day and night shows a gradually decreasing trend. Precipitation in the growth period also showed a decreasing non-linear trend, while the inter-annual variability with period of quasi-3-year and quasi-6-year dominated the variation of temperature and precipitation. The whole growth period was shortened by 10.7 days, and the sowing date was advanced by approximately 11 days. We also found that there was a significant resonance period among temperature, precipitation, and phenology. Overall, a negative correlation between phenology and temperature is evident, while a positive correlation with precipitation is exhibited. The results illustrate that the climate suitability for maize has reduced over the past decades.

Dual-component model of respiratory motion based on the periodic autoregressive moving average (periodic ARMA) method

International Nuclear Information System (INIS)

McCall, K C; Jeraj, R

2007-01-01

A new approach to the problem of modelling and predicting respiration motion has been implemented. This is a dual-component model, which describes the respiration motion as a non-periodic time series superimposed onto a periodic waveform. A periodic autoregressive moving average algorithm has been used to define a mathematical model of the periodic and non-periodic components of the respiration motion. The periodic components of the motion were found by projecting multiple inhale-exhale cycles onto a common subspace. The component of the respiration signal that is left after removing this periodicity is a partially autocorrelated time series and was modelled as an autoregressive moving average (ARMA) process. The accuracy of the periodic ARMA model with respect to fluctuation in amplitude and variation in length of cycles has been assessed. A respiration phantom was developed to simulate the inter-cycle variations seen in free-breathing and coached respiration patterns. At ±14% variability in cycle length and maximum amplitude of motion, the prediction errors were 4.8% of the total motion extent for a 0.5 s ahead prediction, and 9.4% at 1.0 s lag. The prediction errors increased to 11.6% at 0.5 s and 21.6% at 1.0 s when the respiration pattern had ±34% variations in both these parameters. Our results have shown that the accuracy of the periodic ARMA model is more strongly dependent on the variations in cycle length than the amplitude of the respiration cycles

Improving a Complement-fixation Test for Equine Herpesvirus Type-1 by Pretreating Sera with Potassium Periodate to Reduce Non-specific Hemolysis

Science.gov (United States)

BANNAI, Hiroshi; NEMOTO, Manabu; TSUJIMURA, Koji; YAMANAKA, Takashi; KONDO, Takashi; MATSUMURA, Tomio

2013-01-01

Non-specific hemolysis has often been observed during complement-fixation (CF) tests for equine herpesvirus type-1 (EHV-1), even when the sera have virus-specific CF antibodies. This phenomenon has also been reported in CF tests for various infectious diseases of swine. We found that the sera from 22 of 85 field horses (25.9%) showed non-specific hemolysis during conventional CF testing for EHV-1. Because pretreatment of swine sera with potassium periodate (KIO4) improves the CF test for swine influenza, we applied this method to horse sera. As we expected, horse sera treated with KIO4 did not show non-specific hemolysis in the EHV-1 CF test, and precise determination of titers was achieved. PMID:24834005

Genetics Home Reference: Müllerian aplasia and hyperandrogenism

Science.gov (United States)

... do not begin menstruation by age 16 (primary amenorrhea) and will likely never have a menstrual period. ... Encyclopedia: Ovarian Overproduction of Androgens MedlinePlus Encyclopedia: Primary Amenorrhea General Information from MedlinePlus (5 links) Diagnostic Tests ...

Lithuanian on-line periodicals on the World Wide Web

Directory of Open Access Journals (Sweden)

Lina Sarlauskiene

2001-01-01

Full Text Available Deals with Lithuanian full-text electronic periodicals distributed through the World Wide Web. An electronic periodical is usually defined as a regular publication on some particular topic distributed in digital form, chiefly through the Web, but also by electronic mail or digital disk. The author has surveyed 106 publications. Thirty-four are distributed only on the Web, and 72 have printed versions. The number of analysed publications is not very big, but four years of electronic publishing and the variety of periodicals enables us to establish the causes of this phenomenon, the main features of development, and some perspectives. Electronic periodicals were analysed according to their type, purpose, contents, publisher, regularity, language, starting date and place of publication, and other features.

Radiologist involvement is associated with reduced use of MRI in the acute period of low back pain in a non-elderly population

International Nuclear Information System (INIS)

Kumamaru, Kanako K.; Sano, Yukiko; Hori, Masaaki; Takamura, Tomohiro; Irie, Ryusuke; Suzuki, Michimasa; Hagiwara, Akifumi; Kamagata, Koji; Nakanishi, Atsushi; Aoki, Shigeki; Kumamaru, Hiraku

2018-01-01

To test the hypothesis that ''acute-period'' lumbar MRI in non-elderly patients with low back pain is less frequently performed at clinics/hospitals with greater involvement of full-time radiologists in the imaging workflow. In a national-level claims database, we identified 14,819 non-elderly patients (mean age: 38.7±8.0 years) who visited clinics/hospitals for low back pain in 2013-2015. We classified the clinics/hospitals into four groups based on the level of full-time radiologist involvement and MRI ownership, and compared the frequency of acute-period lumbar MRI using hierarchical logistic regression analysis. Patients visiting facilities without a full-time radiologist (n=2105) were significantly (p<0.001) more likely to undergo acute-period MRI than those visiting facilities with ≥1 radiologist partially managing imaging workflow (level-1, n=491) or ≥1 radiologist intensively involved in imaging workflow (level-2, n=1190) (15.7% vs. 6.9% and 7.3%; adjusted odds ratio of no-radiologist versus level-2: 2.93, p=0.018). No difference was observed between level-1 and level-2 involvement. Facilities with no full-time radiologist were more likely to perform acute-period MRI to assess for low back pain, while no difference was seen between facilities with varying levels of radiologist involvement in the imaging workflow. Radiologist involvement may contribute to optimal utilisation of medical imaging. (orig.)

Uncertainty and sensitivity analyses of ballast life-cycle cost and payback period

Energy Technology Data Exchange (ETDEWEB)

McMahon, James E.; Liu, Xiaomin; Turiel, Ike; Hakim, Sajid; Fisher, Diane

2000-06-01

The paper introduces an innovative methodology for evaluating the relative significance of energy-efficient technologies applied to fluorescent lamp ballasts. The method involves replacing the point estimates of life cycle cost of the ballasts with uncertainty distributions reflecting the whole spectrum of possible costs, and the assessed probability associated with each value. The results of uncertainty and sensitivity analyses will help analysts reduce effort in data collection and carry on analysis more efficiently. These methods also enable policy makers to gain an insightful understanding of which efficient technology alternatives benefit or cost what fraction of consumers, given the explicit assumptions of the analysis.

Menstrual knowledge and practices of female adolescents in Vhembe district, Limpopo Province, South Africa

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Dorah U. Ramathuba

2015-11-01

Full Text Available Background: Although sexual issues are openly discussed in the media, sexuality and reproductive functions are treated as taboo. Menstruation is a normal physiologic process, but carries various meanings within cultures and is rarely discussed amongst families and communities.Purpose: This study sought to assess the knowledge and practices of secondary school girls towards menstruation in the Thulamela municipality of Limpopo Province, South Africa. Methods: A quantitative descriptive study design was used and respondents were selected by means of convenience sampling from a population of secondary school girls. The sample consisted of 273 secondary school girls doing Grades 10–12. A self-administered questionnaire was used to collect data, which was analysed by computing frequencies and percentages using the Statistical Package for Social Sciences (SPSS version 12. Findings: The findings revealed that respondents experienced menarche at 13 years and that menstruation is a monthly bleeding (80% that happens to every female; it is a sign of adulthood (91%. 15% reported that it is the removal of dirt from the stomach and abdomen, 67% indicated the source of menstruation being the uterus, 65% the vagina and 13% from the abdomen. 73% reported having fear and anxiety at the first experience of bleeding and that they could not maintain adequate hygienic practices due to a lack of privacy and sanitarytowels. Conclusion: Interventions are needed to increase girls’ opportunities to discuss menstruation and access information from adults including mothers, parents and guardians. School-based sexuality education should be comprehensive, begin early and be regularly repeated.

Chemical and mineralogical analyses of Roman amphorae from Augustan period recovered at the production center of Sant Antoni de Calonge (Gerona, Spain)

International Nuclear Information System (INIS)

Vila Socias, L.; Prats Pico, N.; Buxeda Garrigos, J.

2016-01-01

Amphorae were the most popular transport vessels used to ship wine and other commodities in Antiquity. This paper reports the results of the analyses of 38 samples of several Roman amphorae types recovered at Calonge (Gerona, Spain). Chemical composition of individuals have been obtained by means of XRF. Equivalent firing temperatures have been estimated by XRD and further refiring experiments have been performed. The results suggest the existence of two different clay pastes among individuals analyzed, most of which were fired at the range 900-1000 degree centigrade. Moreover, it is argued that craftsmen did not follow highly standardized paste preparation process during the first activity period of the workshop. The results are discussed in terms of production technology and standardization. (Author)

Drift Compression and Final Focus for Intense Heavy Ion Beams with Non-periodic, Time-dependent Lattice

International Nuclear Information System (INIS)

Hong Qin; Davidson, Ronald C.; Barnard, John J.; Lee, Edward P.

2005-01-01

In the currently envisioned configurations for heavy ion fusion, it is necessary to longitudinally compress the beam bunches by a large factor after the acceleration phase. Because the space-charge force increases as the beam is compressed, the beam size in the transverse direction will increase in a periodic quadrupole lattice. If an active control of the beam size is desired, a larger focusing force is needed to confine the beam in the transverse direction, and a non-periodic quadrupole lattice along the beam path is necessary. In this paper, we describe the design of such a focusing lattice using the transverse envelope equations. A drift compression and final focus lattice should focus the entire beam pulse onto the same focal spot on the target. This is difficult with a fixed lattice, because different slices of the beam may have different perveance and emittance. Four time-dependent magnets are introduced in the upstream of drift compression to focus the entire pulse onto the sam e focal spot. Drift compression and final focusing schemes are developed for a typical heavy ion fusion driver and for the Integrated Beam Experiment (IBX) being designed by the Heavy Ion Fusion Virtual National Laboratory

Precocious Puberty (For Parents)

Science.gov (United States)

... spurt" start of menstruation (her period) acne "mature" body odor In boys, the signs of precocious puberty before ... growth — a growth "spurt" voice deepening acne "mature" body odor Many kids who show some of the early ...

Iron-Deficiency Anemia

Medline Plus

Full Text Available ... stores are developed during the third trimester of pregnancy. Children between ages 1 and 2, especially if ... menstruation, especially if you experience heavy periods. During pregnancy, after delivery, or when breastfeeding you may be ...

Iron-Deficiency Anemia

Medline Plus

Full Text Available ... NHLBI About NHLBI Home Mission and Strategic Vision Leadership Scientific Divisions Operations and Administration Advisory Committees Budget ... some circumstances, including: During menstruation, especially if you experience heavy periods. During pregnancy, after delivery, or when ...

Teaching menstrual care skills to intellectually disabled female students.

Science.gov (United States)

Altundağ, Sebahat; Çalbayram, Nazan Çakırer

2016-07-01

The aim of this study was to teach pad replacement skills to intellectually disabled adolescent female students during their menstruation periods by demonstrating on a dummy. It may be difficult to make intellectually disabled adolescents achieve self-care during menstruation. In addition, there are difficulties experienced in explaining menstruation, such as physical changes and the practice of cleaning during this period. The study used a 'One group pretest and post-test model'. The study was performed in a special educational institution. The population consisted of 77 female students in the high school section. Calculation of a sample size was not attempted, and 54 students with no attendance issues agreed to take part in the study and were included. In this work, we found that pad replacement training significantly changed the scores of mentally disabled adolescents before and after training. Our training yielded positive results, and the population improved their skills at all stages of skill building. Training adolescents with mental disabilities helped them gain hygiene habits. Performance of these trainings occurs at the beginning of menstrual hygiene education. To achieve improved success in life, it is important that adolescents assume the responsibility of self-care and manage sustained care activity on their own. © 2016 John Wiley & Sons Ltd.

Effects of Education Based on Focus Group Discussions on Menstrual Health Behaviors of Female Adolescents in Boarding Centers of the Welfare Organization, Tehran, Iran

Directory of Open Access Journals (Sweden)

Shayesteh Shirzadi

2015-03-01

Full Text Available Background and Objectives: Problems caused by menstruation are common among women. Focus group discussions are a method of data collection in which a small group of participants discuss a specified topic or issue. This study mainly aimed to determine the effects of health education based on focus group discussions on the promotion of health behaviors of female adolescents residing boarding centers of the Welfare Organization (Tehran, Iran during their menstruation periods. Materials and Methods: This quasi-experimental interventional study recruited all eligible 12-19-year-old female residents (n=61 of the boarding centers affiliated to the Welfare Organization, Tehran, Iran. The data collection tool was a questionnaire including demographic information and puberty health behaviors (health behaviors during the menstruation period. The questionnaires were completed through interviews before and one month after training. The educational intervention lasted for three months. Data were analyzed using paired t and Kolmogorov-Smirnov tests in SPSS16. Results: The mean scores of performance increased from 12.11±4.43 before the intervention to 16.50±2.79 after the intervention (P<0.001. Conclusion: Since the educational intervention based on focus group discussions had positive effects on the participants’ puberty health, such discussions are recommended to educate adolescent girls about puberty issues.

Bian Zheng Lun Zhi as a Complementary and Alternative Treatment for Menstrual Cramps in Women with Dysmenorrhea: A Prospective Clinical Observation

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Pin-Yi Lin

2014-01-01

Full Text Available Background. Limited scientific evidence supports the positive effects of traditional Chinese medicine (TCM for treating dysmenorrhea. Thus, an observation period of 3 months could verify the ancient indication that TCM treatments effectively alleviate menstrual cramps in women with primary dysmenorrhea or endometriosis. Methods. A prospective, nonrandomized study (primary dysmenorrhea and endometriosis groups was conducted in women with dysmenorrhea for more than three consecutive menstrual cycles. All patients received TCM prescriptions based on bian zheng lun zhi theory 14 days before menstruation for a period of 12 weeks. Pain intensity was evaluated using a 10-cm visual analogue scale and two validated questionnaires (the Menstrual Distress Questionnaire and the World Health Organization Quality of Life questionnaire. Results. Of the initial 70 intent-to-treat participants, the women with dysmenorrhea reported significant alleviation of cramps during menstruation after the 12-week TCM treatment. Mixed model analysis revealed that TCM prescriptions were more effective in alleviating fatigue, hot flashes, dizziness, painful breasts, excitement, and irritability in the primary dysmenorrhea group (N=36 than in the endometriosis group (N=34. Conclusion. TCM prescriptions based on syndrome differentiation theory might be a potentially viable choice for treating painful menstruation and premenstrual symptoms after ruling out endometriosis.

An empirical evaluation of landscape energetic models: Mallard and American black duck space use during the non-breeding period

Science.gov (United States)

Beatty, William S.; Webb, Elisabeth B.; Kesler, Dylan C.; Naylor, Luke W.; Raedeke, Andrew H.; Humburg, Dale D.; Coluccy, John M.; Soulliere, G.

2015-01-01

Bird conservation Joint Ventures are collaborative partnerships between public agencies and private organizations that facilitate habitat management to support waterfowl and other bird populations. A subset of Joint Ventures has developed energetic carrying capacity models (ECCs) to translate regional waterfowl population goals into habitat objectives during the non-breeding period. Energetic carrying capacity models consider food biomass, metabolism, and available habitat to estimate waterfowl carrying capacity within an area. To evaluate Joint Venture ECCs in the context of waterfowl space use, we monitored 33 female mallards (Anas platyrhynchos) and 55 female American black ducks (A. rubripes) using global positioning system satellite telemetry in the central and eastern United States. To quantify space use, we measured first-passage time (FPT: time required for an individual to transit across a circle of a given radius) at biologically relevant spatial scales for mallards (3.46 km) and American black ducks (2.30 km) during the non-breeding period, which included autumn migration, winter, and spring migration. We developed a series of models to predict FPT using Joint Venture ECCs and compared them to a biological null model that quantified habitat composition and a statistical null model, which included intercept and random terms. Energetic carrying capacity models predicted mallard space use more efficiently during autumn and spring migrations, but the statistical null was the top model for winter. For American black ducks, ECCs did not improve predictions of space use; the biological null was top ranked for winter and the statistical null was top ranked for spring migration. Thus, ECCs provided limited insight into predicting waterfowl space use during the non-breeding season. Refined estimates of spatial and temporal variation in food abundance, habitat conditions, and anthropogenic disturbance will likely improve ECCs and benefit conservation planners

Detecting unstable periodic orbits of nonlinear mappings by a novel quantum-behaved particle swarm optimization non-Lyapunov way

International Nuclear Information System (INIS)

Gao Fei; Gao Hongrui; Li Zhuoqiu; Tong Hengqing; Lee, Ju-Jang

2009-01-01

It is well known that set of unstable periodic orbits (UPOs) can be thought of as the skeleton for the dynamics. However, detecting UPOs of nonlinear map is one of the most challenging problems of nonlinear science in both numerical computations and experimental measures. In this paper, a new method is proposed to detect the UPOs in a non-Lyapunov way. Firstly three special techniques are added to quantum-behaved particle swarm optimization (QPSO), a novel mbest particle, contracting the searching space self-adaptively and boundaries restriction (NCB), then the new method NCB-QPSO is proposed. It can maintain an effective search mechanism with fine equilibrium between exploitation and exploration. Secondly, the problems of detecting the UPOs are converted into a non-negative functions' minimization through a proper translation in a non-Lyapunov way. Thirdly the simulations to 6 benchmark optimization problems and different high order UPOs of 5 classic nonlinear maps are done by the proposed method. And the results show that NCB-QPSO is a successful method in detecting the UPOs, and it has the advantages of fast convergence, high precision and robustness.

Adjustment of interbank lending in pre- and post-regulation periods: Empirical analysis of Vietnamese commercial banks

Directory of Open Access Journals (Sweden)

Ho Thanh Tung

2017-10-01

Full Text Available This article aims to analyze the interbank lending adjustment during the period when Vietnamese commercial banks are compliant with some parts of the Basel regulation framework. A pilot regulation period has started in 2011 and full application will be effective by the end of 2018. Partial adjustment models and variance decomposition are used for the analyses. In the analysis of the quarterly released financial statements of Vietnamese commercial banks in the period from 2008/Q1 to 2015/Q4, the empirical evidence showed that throughout the period, lending to non-bank and high liquidity assets contributed to the adjustment in both long run and short run with a negative association. In addition, the loan loss allowance contributed to the adjustment in the post-regulation period only with a positive association. These highly contributing factors also show a potential shock after the adjustment of the interbank lending. The results imply there is a need for interbank lending portfolio report and an efficient control over the IRB of Vietnamese commercial banks.

Carbon tape microsampling for non-destructive analyses of artefacts

Czech Academy of Sciences Publication Activity Database

Bartůněk, V.; Varadzin, Ladislav; Zavřel, Jan

-, - (2017) ISSN 1866-9557 R&D Projects: GA ČR(CZ) GAP405/10/2334 Institutional support: RVO:67985912 Keywords : microsampling * SEM-EDS * conducting SEM carbon tape * non-ferrous metallurgy * moulds * Early Middle Ages Subject RIV: AC - Archeology, Anthropology, Ethnology OBOR OECD: Archaeology Impact factor: 1.844, year: 2016

Psychosocial and Cultural Factors Influencing Expectations of Menarche: A Study on Chinese Premenarcheal Teenage Girls

Science.gov (United States)

Yeung, Dannii Y. L.; Tang, Catherine So-kum; Lee, Antoinette

2005-01-01

This study explored how psychosocial and cultural factors influenced expectations of menarche among 476 Chinese premenarcheal teenage girls. Results showed that participants' expectations of menarche were largely negative and heavily influenced by cultural beliefs about menstruation. Findings of hierarchical regression analyses revealed that…

20 CFR 655.205 - Recruitment period.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Recruitment period. 655.205 Section 655.205... FOREIGN WORKERS IN THE UNITED STATES Labor Certification Process for Logging Employment and Non-H-2A Agricultural Employment § 655.205 Recruitment period. (a) If the OFLC Administrator determines that the...

Sensitivity analysis of periodic errors in heterodyne interferometry

International Nuclear Information System (INIS)

Ganguly, Vasishta; Kim, Nam Ho; Kim, Hyo Soo; Schmitz, Tony

2011-01-01

Periodic errors in heterodyne displacement measuring interferometry occur due to frequency mixing in the interferometer. These nonlinearities are typically characterized as first- and second-order periodic errors which cause a cyclical (non-cumulative) variation in the reported displacement about the true value. This study implements an existing analytical periodic error model in order to identify sensitivities of the first- and second-order periodic errors to the input parameters, including rotational misalignments of the polarizing beam splitter and mixing polarizer, non-orthogonality of the two laser frequencies, ellipticity in the polarizations of the two laser beams, and different transmission coefficients in the polarizing beam splitter. A local sensitivity analysis is first conducted to examine the sensitivities of the periodic errors with respect to each input parameter about the nominal input values. Next, a variance-based approach is used to study the global sensitivities of the periodic errors by calculating the Sobol' sensitivity indices using Monte Carlo simulation. The effect of variation in the input uncertainty on the computed sensitivity indices is examined. It is seen that the first-order periodic error is highly sensitive to non-orthogonality of the two linearly polarized laser frequencies, while the second-order error is most sensitive to the rotational misalignment between the laser beams and the polarizing beam splitter. A particle swarm optimization technique is finally used to predict the possible setup imperfections based on experimentally generated values for periodic errors

Sensitivity analysis of periodic errors in heterodyne interferometry

Science.gov (United States)

Ganguly, Vasishta; Kim, Nam Ho; Kim, Hyo Soo; Schmitz, Tony

2011-03-01

Periodic errors in heterodyne displacement measuring interferometry occur due to frequency mixing in the interferometer. These nonlinearities are typically characterized as first- and second-order periodic errors which cause a cyclical (non-cumulative) variation in the reported displacement about the true value. This study implements an existing analytical periodic error model in order to identify sensitivities of the first- and second-order periodic errors to the input parameters, including rotational misalignments of the polarizing beam splitter and mixing polarizer, non-orthogonality of the two laser frequencies, ellipticity in the polarizations of the two laser beams, and different transmission coefficients in the polarizing beam splitter. A local sensitivity analysis is first conducted to examine the sensitivities of the periodic errors with respect to each input parameter about the nominal input values. Next, a variance-based approach is used to study the global sensitivities of the periodic errors by calculating the Sobol' sensitivity indices using Monte Carlo simulation. The effect of variation in the input uncertainty on the computed sensitivity indices is examined. It is seen that the first-order periodic error is highly sensitive to non-orthogonality of the two linearly polarized laser frequencies, while the second-order error is most sensitive to the rotational misalignment between the laser beams and the polarizing beam splitter. A particle swarm optimization technique is finally used to predict the possible setup imperfections based on experimentally generated values for periodic errors.

Primary gastrointestinal non-Hodgkin's lymphoma in adults

DEFF Research Database (Denmark)

Hansen, P B; Vogt, K C; Skov, Robert L

1998-01-01

OBJECTIVES: To analyse the clinical course and the histopathology of primary gastrointestinal non-Hodgkin's lymphoma (GI-NHL) in adult patients and to investigate a possible impact of Helicobacter pylori. DESIGN/SETTING: Retrospective study of all adult patients in Copenhagen county diagnosed...... during a 6-year period with NHL. SUBJECTS: A total of 55 patients with GI-NHL diagnosed during the period from 1985 to the end of 1990. RESULTS: Twenty-eight patients had primary lymphoma in the stomach, 14 in the small intestine, 11 in the large intestine and two patients had multifocal involvement....... The dominant presenting symptoms were abdominal pain, weight loss, diarrhoea, constipation and fatigue. Acute emergency problems such as severe haemorrhage or perforation at initial presentation were unusual. According to the revised European-American lymphoma (REAL) classification, diffuse large B...

Detecting periodicities with Gaussian processes

Directory of Open Access Journals (Sweden)

Nicolas Durrande

2016-04-01

Full Text Available We consider the problem of detecting and quantifying the periodic component of a function given noise-corrupted observations of a limited number of input/output tuples. Our approach is based on Gaussian process regression, which provides a flexible non-parametric framework for modelling periodic data. We introduce a novel decomposition of the covariance function as the sum of periodic and aperiodic kernels. This decomposition allows for the creation of sub-models which capture the periodic nature of the signal and its complement. To quantify the periodicity of the signal, we derive a periodicity ratio which reflects the uncertainty in the fitted sub-models. Although the method can be applied to many kernels, we give a special emphasis to the Matérn family, from the expression of the reproducing kernel Hilbert space inner product to the implementation of the associated periodic kernels in a Gaussian process toolkit. The proposed method is illustrated by considering the detection of periodically expressed genes in the arabidopsis genome.

Frequency shift of the Bragg and Non-Bragg backscattering from periodic water wave

Science.gov (United States)

Wen, Biyang; Li, Ke

2016-08-01

Doppler effect is used to measure the relative speed of a moving target with respect to the radar, and is also used to interpret the frequency shift of the backscattering from the ocean wave according to the water-wave phase velocity. The widely known relationship between the Doppler shift and the water-wave phase velocity was deduced from the scattering measurements data collected from actual sea surface, and has not been verified under man-made conditions. Here we show that this ob- served frequency shift of the scattering data from the Bragg and Non-Bragg water wave is not the Doppler shift corresponding to the water-wave phase velocity as commonly believed, but is the water-wave frequency and its integral multiple frequency. The power spectrum of the backscatter from the periodic water wave consists of serials discrete peaks, which is equally spaced by water wave frequency. Only when the water-wave length is the integer multiples of the Bragg wave, and the radar range resolution is infinite, does the frequency shift of the backscattering mathematically equal the Doppler shift according to the water-wave phase velocity.

Proximate Composition, Mineral Content and Fatty Acids Analyses of Aromatic and Non-Aromatic Indian Rice

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Deepak Kumar Verma

2017-01-01

Full Text Available Awareness on nutritive value and health benefits of rice is of vital importance in order to increase the consumption of rice in daily diet of the human beings. In this study, a total of six aromatic and two non-aromatic rice accessions grown in India were analysed for their nutritional quality attributes including proximate composition, mineral contents and fatty acids. Data with three replications were used to measure Pearson's simple correlation co-efficient in order to establish the relationship among various nutritional quality attributes. The result on proximate composition showed that Govind Bhog had the highest moisture (13.57% and fat (0.92% content, which signifies its tasty attribute. Badshah Bhog exhibited the highest fibre content (0.85%, carbohydrate content (82.70% and food energy (365.23 kCal per 100 g. Among the minerals, the higher Ca (98.75 mg/kg, Zn (17.00 mg/kg and Fe (31.50 mg/kg were in Gopal Bhog, whereas the highest Na (68.85 mg/kg was in Badshah Bhog, the highest K (500.00 mg/kg was in Swetganga, Khushboo and Sarbati. The highest contents of unsaturated fatty acids viz. oleic acid (49.14%, linoleic acid (46.99% and linolenic acid (1.27% were found in Sarbati, whereas the highest content of saturated fatty acids viz. myristic acid (4.60% and palmitic acid (31.91% were found in Govind Bhog and stearic acid (6.47% in Todal. The identified aromatic rice accessions Gopal Bhog, Govind Bhog and Badshah Bhog and non-aromatic rice accession Sarbati were found nutritionally superior among all eight tested accessions. The nutritional quality oriented attributes in this study were competent with recognized prominent aromatic and non-aromatic rice accessions as an index of their nutritional worth and recommend to farmers and consumers which may be graded as export quality rice with good unique nutritional values in international market.

Economic Crises in the Results of the Non-Financial Corporations Sector in the Czech Republic

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Stanislava Hronová

2012-09-01

Full Text Available In connection with the fi nancial and subsequent economic crisis, the role of non-fi nancial corporations is often discussed and the causes and eff ects of the crisis are analysed. Viewing two critical periods of economic development in the Czech Republic – the first in 1997–1998, and the second in 2009–2010 – we can see that non-financial corporations generated a high level of net borrowing in the fi rst instance and, on the contrary, a high level of net lending in the second instance. Regardless of the diff erent causes of the crises in the abovementioned periods, a natural question arises: what kind of transformation took place in the economic behaviourof non-fi nancial corporations between 1998 and 2008? Consequently, what was the source of their overall (and in a time of crisis, surprising profi t in the crisis years of 2009 and 2010. When analysing the economic behaviour of the non-fi nancial corporations sector in the Czech Republic we will, naturally, base our considerations on the data from national accounts of the Czech Republic as published by the Czech Statistical Office and will also utilise the usual relative indices immediately implied by the national account ones, as well as indices whose construction is closer to the evaluation usual in corporate practice.

Removal of gas phase low-concentration toluene over Mn, Ag and Ce modified HZSM-5 catalysts by periodical operation of adsorption and non-thermal plasma regeneration.

Science.gov (United States)

Wang, Wenzheng; Wang, Honglei; Zhu, Tianle; Fan, Xing

2015-07-15

Ag/HZSM-5, Mn/HZSM-5, Ce/HZSM-5, Ag-Mn/HZSM-5 and Ce-Mn/HZSM-5 were prepared by impregnation method. Both their adsorption capacity and catalytic activity were investigated for the removal of gas phase low-concentration toluene by periodical operation of adsorption and non-thermal plasma regeneration. Results show that catalysts loaded with Ag (Ag/HZSM-5 and Ag-Mn/HZSM-5) had larger adsorption capacity for toluene than the other catalysts. And Ag-Mn/HZSM-5 displayed the best catalytic performance for both toluene oxidation by non-thermal plasma and byproducts suppression. On the other hand, the deactivated catalyst can be fully regenerated by calcining in air stream when its adsorption capacity and catalytic activity of the Ag-Mn/HZSM-5 catalyst was found to be decreased after 10 cycles of periodical adsorption and non-thermal regeneration. Copyright © 2015. Published by Elsevier B.V.

Migraine Headaches

Science.gov (United States)

... migraine triggers include: stress menstruation (periods) skipping meals dehydration too much caffeine (more than 200 mg a day, such as the amount of caffeine in energy drinks) some foods (alcohol, cheese, citrus fruits, pizza, chocolate, ice cream, lunch meats and hot ...

Direct comparison of risk-adjusted and non-risk-adjusted CUSUM analyses of coronary artery bypass surgery outcomes.

Science.gov (United States)

Novick, Richard J; Fox, Stephanie A; Stitt, Larry W; Forbes, Thomas L; Steiner, Stefan

2006-08-01

We previously applied non-risk-adjusted cumulative sum methods to analyze coronary bypass outcomes. The objective of this study was to assess the incremental advantage of risk-adjusted cumulative sum methods in this setting. Prospective data were collected in 793 consecutive patients who underwent coronary bypass grafting performed by a single surgeon during a period of 5 years. The composite occurrence of an "adverse outcome" included mortality or any of 10 major complications. An institutional logistic regression model for adverse outcome was developed by using 2608 contemporaneous patients undergoing coronary bypass. The predicted risk of adverse outcome in each of the surgeon's 793 patients was then calculated. A risk-adjusted cumulative sum curve was then generated after specifying control limits and odds ratio. This risk-adjusted curve was compared with the non-risk-adjusted cumulative sum curve, and the clinical significance of this difference was assessed. The surgeon's adverse outcome rate was 96 of 793 (12.1%) versus 270 of 1815 (14.9%) for all the other institution's surgeons combined (P = .06). The non-risk-adjusted curve reached below the lower control limit, signifying excellent outcomes between cases 164 and 313, 323 and 407, and 667 and 793, but transgressed the upper limit between cases 461 and 478. The risk-adjusted cumulative sum curve never transgressed the upper control limit, signifying that cases preceding and including 461 to 478 were at an increased predicted risk. Furthermore, if the risk-adjusted cumulative sum curve was reset to zero whenever a control limit was reached, it still signaled a decrease in adverse outcome at 166, 653, and 782 cases. Risk-adjusted cumulative sum techniques provide incremental advantages over non-risk-adjusted methods by not signaling a decrement in performance when preoperative patient risk is high.

How periodic are terahertz quantum cascade lasers?

International Nuclear Information System (INIS)

Kubis, T; Vogl, P

2009-01-01

We apply a novel non-equilibrium Green's function method for open quantum devices to analyze quantum cascade lasers. We find the carrier distribution in typical resonant phonon THz-QCLs to develop a periodicity that differs from the geometric periodicity of the QCL. We propose a design improvement that thermalizes electrons at threshold bias and thereby pins the electron density to the QCL periodicity.

Bone tuberculosis in Roman Period Pannonia (western Hungary

Directory of Open Access Journals (Sweden)

Tamás Hajdu

2012-12-01

Full Text Available The purpose of this study was to analyse a skeleton (adult female, 25-30 years that presented evidence of tuberculous spondylitis. The skeleton, dated from the Roman Period (III-VI centuries, was excavated near the town of Győr, in western Hungary. The skeleton was examined by gross observation supplemented with mycolic acid and proteomic analyses using MALDI-TOF/TOF tandem mass spectrometry. The biomolecular analyses supported the morphological diagnosis.

Allowable warm ischemic time and morphological and biochemical changes in uterine ischemia/reperfusion injury in cynomolgus macaque: a basic study for uterus transplantation.

Science.gov (United States)

Kisu, Iori; Umene, Kiyoko; Adachi, Masataka; Emoto, Katsura; Nogami, Yuya; Banno, Kouji; Itagaki, Iori; Kawamoto, Ikuo; Nakagawa, Takahiro; Narita, Hayato; Yoshida, Atsushi; Tsuchiya, Hideaki; Ogasawara, Kazumasa; Aoki, Daisuke

2017-10-01

How long is the allowable warm ischemic time of the uterus and what morphological and biochemical changes are caused by uterine ischemia/reperfusion injury in cynomolgus macaques? Warm ischemia in the uterus of cynomolgus macaques is tolerated for up to 4 h and reperfusion after uterine ischemia caused no further morphological and biochemical changes. Uterus transplantation is a potential option for women with uterine factor infertility. The allowable warm ischemic time and ischemia/reperfusion injury of the uterus in humans and non-human primates is unknown. This experimental study included 18 female cynomolgus macaques with periodic menstruation. Animals were divided into six groups of three monkeys each: a control group and groups with uterine ischemia for 0.5, 1, 2, 4 and 8 h. Biopsies of uterine tissues were performed before blood flow blockage, after each blockage time, and after reperfusion for 3 h. Blood sampling was performed after each blockage time, and after reperfusion for 5, 15 and 30 min for measurement of biochemical data. Resumption of menstruation was monitored after the surgical procedure. Morphological, physiological and biochemical changes after ischemia and reperfusion were evaluated. Mild muscle degeneration and zonal degeneration were observed in all animals subjected to warm ischemia for 4 or 8 h, but there were no marked differences in the appearance of specimens immediately after ischemia and after reperfusion for 3 h in animals subjected to 4 or 8 h of warm ischemia. There were no significant changes in any biochemical parameters at any time point in each group. Periodical menstruation resumed in all animals with warm ischemia up to 4 h, but did not recover in animals with warm ischemia for 8 h with atrophic uteri. Warm ischemia in actual transplantation was not exactly mimicked in this study because uteri were not perfused, cooled, transplanted or reanastomosed with vessels. Results in non-human primates cannot always be extrapolated to

A condition-based maintenance policy with non-periodic inspections for a two-unit series system

International Nuclear Information System (INIS)

Castanier, B.; Grall, A.; Berenguer, C.

2005-01-01

This paper considers a condition-based maintenance policy for a two-unit deteriorating system. Each unit is subject to gradual deterioration and is monitored by sequential non-periodic inspections. It can be maintained by good as new preventive or corrective replacements. Every inspection or replacement entails a set-up cost and a component-specific unit cost but if actions on the two components are combined, the set-up cost is charged only once. A parametric maintenance decision framework is proposed to coordinate inspection/replacement of the two components and minimize the long-run maintenance cost of the system. A stochastic model is developed on the basis of the semi-regenerative properties of the maintained system state and the associated cost model is used to assess and optimize the performance of the maintenance model. Numerical experiments emphasize the interest of a control of the operation groupings

Periodicity in Age-Resolved Populations

Science.gov (United States)

Esipov, Sergei

We discuss the interplay between the non-linear diffusion and age-resolved population dynamics. Depending on the age properties of collective migration the system may exhibit continuous joint expansion of all ages or continuous expansion with age segregation. Between these two obvious limiting regimes there is an interesting window of periodic expansion, which has been previously used by us in modeling bacterial colonies of Proteus mirabilis. In order to test whether the age-dependent collective migration leads to periodicity in other systems we performed a Fourier analysis of historical data on ethnic expansions and found multiple co-existing periods of activity.

Changes in respiratory and non-respiratory symptoms in occupants of a large office building over a period of moisture damage remediation attempts

Science.gov (United States)

Cho, Sook Ja; White, Sandra K.; Cox-Ganser, Jean M.

2018-01-01

There is limited information on the natural history of building occupants’ health in relation to attempts to remediate moisture damage. We examined changes in respiratory and non-respiratory symptoms in 1,175 office building occupants over seven years with multiple remediation attempts. During each of four surveys, we categorized participants using a severity score: 0 = asymptomatic; 1 = mild, symptomatic in the last 12 months, but not frequently in the last 4 weeks; 2 = severe, symptomatic at least once weekly in the last 4 weeks. Building-related symptoms were defined as improving away from the building. We used random intercept models adjusted for demographics, smoking, building tenure, and microbial exposures to estimate temporal changes in the odds of building-related symptoms or severity scores independent of the effect of microbial exposures. Trend analyses of combined mild/severe symptoms showed no changes in the odds of respiratory symptoms but significant improvement in non-respiratory symptoms over time. Separate analyses showed increases in the odds of severe respiratory symptoms (odds ratio/year = 1.15‒1.16, p-valuesremediation efforts might not be effective in improving occupants’ health. PMID:29324816

Energy and exergy analyses of energy consumptions in the industrial sector in South Africa

International Nuclear Information System (INIS)

Oladiran, M.T.; Meyer, J.P.

2007-01-01

The energy-utilization over a 10-year period (1994-2003) has been analysed for the South African industrial sector, which consumes more primary energy than any other sector of the economy. Four principal sub-sectors, namely iron and steel, chemical and petrochemical, mining and quarrying, and non-ferrous metals/non-metallic minerals were considered in this study. Primary-energy utilization data were used to calculate the weighted mean energy and exergy efficiencies for the sub-sectors and then overall values for the industrial sector were obtained. The results indicate that exergy efficiency is considerably lower than energy efficiency in all the sub-sectors, particularly in mining and quarrying processes, for which the values were approximately 83% and 16%, respectively. The performance of exergy utilization in the industrial sector can be improved by introducing various conservation strategies. Results from this study were compared with those for other countries

Complexity analyses show two distinct types of nonlinear dynamics in short heart period variability recordings

Science.gov (United States)

Porta, Alberto; Bari, Vlasta; Marchi, Andrea; De Maria, Beatrice; Cysarz, Dirk; Van Leeuwen, Peter; Takahashi, Anielle C. M.; Catai, Aparecida M.; Gnecchi-Ruscone, Tomaso

2015-01-01

Two diverse complexity metrics quantifying time irreversibility and local prediction, in connection with a surrogate data approach, were utilized to detect nonlinear dynamics in short heart period (HP) variability series recorded in fetuses, as a function of the gestational period, and in healthy humans, as a function of the magnitude of the orthostatic challenge. The metrics indicated the presence of two distinct types of nonlinear HP dynamics characterized by diverse ranges of time scales. These findings stress the need to render more specific the analysis of nonlinear components of HP dynamics by accounting for different temporal scales. PMID:25806002

Ultrastructural analyses of blood capillaries of ovary of 20-days albino rats foetus under their irradiation in different periods of embryogenesis

International Nuclear Information System (INIS)

Ablekovskaya, O.N.; Amvros'ev, A.P.

1999-01-01

The character and direction of structural transformations of blood capillaries of micro circulatory channel of 20-days white rat foetus in normal conditions and after single external 0,5 Gy dose irradiation by 10 and 14 days of embryogenesis were examined. Electron-microscopical, stereo logical and statistical analyses were used. The peculiarities of reactions of hemo capillaries and their cell structure to gamma-rays action in embryogenesis were revealed. It was shown the increase of diameters of capillaries, extension of section area of cytoplasm of endotheliocytes, diminution the size of nuclei of these cells. Polyploid endotheliocytes were found in the experimental conditions. Prenatal acute irradiation in low doses leaded to reduction of the number of microvessels and mitochondria in cytoplasm of cells of blood capillaries in ovary of rat foetus. These results revealed that low dose ionizing radiation changed the morphological expression of important synthetic, transport and energy processes in capillary cells of ovary in fetal period of ontogenesis

How periodic are terahertz quantum cascade lasers?

Energy Technology Data Exchange (ETDEWEB)

Kubis, T; Vogl, P, E-mail: tillmann.kubis@wsi.tum.d [Walter Schottky Institute, Technische Universitaet Muenchen, Am Coulombwall 3, 85748 Garching (Germany)

2009-11-15

We apply a novel non-equilibrium Green's function method for open quantum devices to analyze quantum cascade lasers. We find the carrier distribution in typical resonant phonon THz-QCLs to develop a periodicity that differs from the geometric periodicity of the QCL. We propose a design improvement that thermalizes electrons at threshold bias and thereby pins the electron density to the QCL periodicity.

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African Journals Online (AJOL)

unprotected coitus. Prior to presentation, she developed irregular menstruation with occasional periods of amenorrhea and oligomenorrhea of six months duration. On account of these worrisome symptoms she had presented at several hospitals within and outside. Rivers State where several investigations were conducted.

Changes in respiratory and non-respiratory symptoms in occupants of a large office building over a period of moisture damage remediation attempts.

Science.gov (United States)

Park, Ju-Hyeong; Cho, Sook Ja; White, Sandra K; Cox-Ganser, Jean M

2018-01-01

There is limited information on the natural history of building occupants' health in relation to attempts to remediate moisture damage. We examined changes in respiratory and non-respiratory symptoms in 1,175 office building occupants over seven years with multiple remediation attempts. During each of four surveys, we categorized participants using a severity score: 0 = asymptomatic; 1 = mild, symptomatic in the last 12 months, but not frequently in the last 4 weeks; 2 = severe, symptomatic at least once weekly in the last 4 weeks. Building-related symptoms were defined as improving away from the building. We used random intercept models adjusted for demographics, smoking, building tenure, and microbial exposures to estimate temporal changes in the odds of building-related symptoms or severity scores independent of the effect of microbial exposures. Trend analyses of combined mild/severe symptoms showed no changes in the odds of respiratory symptoms but significant improvement in non-respiratory symptoms over time. Separate analyses showed increases in the odds of severe respiratory symptoms (odds ratio/year = 1.15‒1.16, p-values<0.05) and severity scores (0.02/year, p-values<0.05) for wheezing and shortness of breath on exertion, due to worsening of participants in the mild symptom group. For non-respiratory symptoms, we found no changes in the odds of severe symptoms but improvement in severity scores (-0.04‒-0.01/year, p-values<0.05) and the odds for mild fever and chills, excessive fatigue, headache, and throat symptoms (0.65-0.79/year, p-values<0.05). Our study suggests that after the onset of respiratory and severe non-respiratory symptoms associated with dampness/mold, remediation efforts might not be effective in improving occupants' health.

Environmentally Driven Increases in Type 2 Diabetes and Obesity in Pima Indians and Non-Pimas in Mexico Over a 15-Year Period: The Maycoba Project.

Science.gov (United States)

Esparza-Romero, Julian; Valencia, Mauro E; Urquidez-Romero, Rene; Chaudhari, Lisa S; Hanson, Robert L; Knowler, William C; Ravussin, Eric; Bennett, Peter H; Schulz, Leslie O

2015-11-01

The global epidemics of type 2 diabetes and obesity have been attributed to the interaction between lifestyle changes and genetic predisposition to these diseases. We compared the prevalences of type 2 diabetes and obesity in Mexican Pima Indians, presumed to have a high genetic predisposition to these diseases, to those in their non-Pima neighbors, both of whom over a 15-year period experienced a transition from a traditional to a more modern lifestyle. Prevalence of diabetes, impaired fasting glucose, impaired glucose tolerance, and obesity in Mexican Pimas (n = 359) and non-Pima Mexicans (n = 251) were determined in 2010 using methods identical to those used in 1995. During this 15-year period, age-adjusted diabetes prevalence was unchanged in Pima men (5.8% in 1995 vs. 6.1% in 2010) yet increased in non-Pima men from 0.0 to 8.6% (P obesity increased significantly in all groups (6.6 vs. 15.7% in Pima men; 8.5 vs. 20.5% in non-Pima men; 18.9. vs 36.3% in Pima women; 29.5 vs. 42.9% in non-Pima women). Type 2 diabetes prevalence increased between 1995 and 2010 in non-Pima men, and to a lesser degree in women of both groups, but it did not increase in Pima men. Prevalence of obesity increased among Pimas and non-Pimas of both sexes. These changes occurred concomitantly with an environmental transition from a traditional to a more modernized lifestyle. © 2015 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.

Numerical Analyses of the Non-Newtonian Flow Performance and Thermal Effect on a Bearing Coated with a High Tin Content

Directory of Open Access Journals (Sweden)

K. Mehala

2016-12-01

Full Text Available The hydrodynamic bearings are stressed by severe workings conditions, such as speed, load, and the oil will be increasingly solicit by pressure and shear. The Newtonian behavior is far from being awarded in this case, the most loaded bearings operating at very high speeds; the shear rate of the oil is of higher order. A numerical analysis of the behavior of non-Newtonian fluid for plain cylindrical journal bearing finite dimension coated with antifriction material with a high tin content, for to facilitate the accommodation of the surfaces and save the silk of the shaft in the case of a contact. this analyses is implemented using the code-ANSYS CFX, by solving the energy equation with the finite difference method, considering that laminar regime and the fluid is non Newtonian by using the power law Ostwald model, the coefficient n is equal to 1.25 and for different model such as Bingham, cross and Hereshek-Bulkley model. This study aims to better predict the non-Newtonian behavior of the oil film in bearings operating under more severe conditions. The purpose conducted during this study is to predict the effect of non-Newtonian behavior of the film; the journal bearing operating under severe conditions, the speed of rotation varies from 1000 to 9000 rpm and the bearing working under radial load 2 to 10 kN. Temperature and the pressure within the fluid film assumed non-Newtonian are high, with a coefficient n greater than 1 that is to say for viscoelastic fluids.

Decomposing the gap in missed opportunities for vaccination between poor and non-poor in sub-Saharan Africa: A multicountry analyses.

Science.gov (United States)

Ndwandwe, Duduzile; Uthman, Olalekan A; Adamu, Abdu; Sambala, Evanson Z; Wiyeh, Alison B; Olukade, Tawa; Bishwajit, Ghose; Yaya, Sanni; Okwo-Bele, Jean-Marie; Wiysonge, Charles S

2018-04-24

Understanding the gaps in missed opportunities for vaccination (MOV) between poor and non-poor in sub-Saharan Africa (SSA) would enable an understanding of factors associated with interventions for improving immunisation coverage to achieving universal childhood immunisation. We aimed to conduct a multicountry analyses to decompose the gap in MOV between poor and non-poor in SSA. We used cross-sectional data from 35 Demographic and Health Surveys in SSA conducted between 2007 and 2016. Descriptive statistics used to understand the gap in MOV between the urban poor and non-poor, and across the selected covariates. Out of the 35 countries included in this analysis, 19 countries showed pro-poor inequality, 5 showed pro-non-poor inequality and remaining 11 countries showed no statistically significant inequality. Among the countries with statistically significant pro-illiterate inequality, the risk difference ranged from 4.2% in DR Congo to 20.1% in Kenya. Important factors responsible for the inequality varied across countries. In Madagascar, the largest contributors to inequality in MOV were media access, number of under-five children, and maternal education. However, in Liberia media access narrowed inequality in MOV between poor and non-poor households. The findings indicate that in most SSA countries, children belonging to poor households are most likely to have MOV and that socio-economic inequality in is determined not only by health system functions, but also by factors beyond the scope of health authorities and care delivery system. The findings suggest the need for addressing social determinants of health.

Menstruation.

Science.gov (United States)

Henderson, Paula

This autoinstructional program deals with the study of human develpment with emphasis on the female reproductive system. It is considered as part of a secondary school human anatomy and physiology course. Students should have a previous knowledge of the parts of the female reproductive organs or system. Behavioral objectives are suggested. The…

Non-local Thermodynamic Equilibrium Abundance Analyses of the Extreme Helium Stars V652 Her and HD 144941

International Nuclear Information System (INIS)

Pandey, Gajendra; Lambert, David L.

2017-01-01

Optical high-resolution spectra of V652 Her and HD 144941, the two extreme helium stars with exceptionally low C/He ratios, have been subjected to a non-LTE abundance analysis using the tools TLUSTY and SYNSPEC. Defining atmospheric parameters were obtained from a grid of non-LTE atmospheres and a variety of spectroscopic indicators including He i and He ii line profiles, and the ionization equilibrium of ion pairs such as C ii/C iii and N ii/N iii. The various indicators provide a consistent set of atmospheric parameters: T eff = 25,000 ± 300 K, log g = 3.10 ± 0.12(cgs), and ξ = 13 ± 2 km s −1 are provided for V652 Her, and T eff = 22,000 ± 600 K, log g = 3.45 ± 0.15 (cgs), and ξ = 10 km s −1 are provided for HD 144941. In contrast to the non-LTE analyses, the LTE analyses—LTE atmospheres and an LTE line analysis—with the available indicators do not provide a consistent set of atmospheric parameters. The principal non-LTE effect on the elemental abundances is on the neon abundance. It is generally considered that these extreme helium stars with their very low C/He ratio result from the merger of two helium white dwarfs. Indeed, the derived composition of V652 Her is in excellent agreement with predictions by Zhang and Jeffery, who model the slow merger of helium white dwarfs; a slow merger results in the merged star having the composition of the accreted white dwarf. In the case of HD 144941, which appears to have evolved from metal-poor stars, a slow merger is incompatible with the observed composition but variations of the merger rate may account for the observed composition. More detailed theoretical studies of the merger of a pair of helium white dwarfs are to be encouraged.

Non-local Thermodynamic Equilibrium Abundance Analyses of the Extreme Helium Stars V652 Her and HD 144941

Energy Technology Data Exchange (ETDEWEB)

Pandey, Gajendra [Indian Institute of Astrophysics, Bangalore, 560034 (India); Lambert, David L., E-mail: pandey@iiap.res.in, E-mail: dll@astro.as.utexas.edu [The W.J. McDonald Observatory and Department of Astronomy, University of Texas at Austin, Austin, TX 78712-1083 (United States)

2017-10-01

Optical high-resolution spectra of V652 Her and HD 144941, the two extreme helium stars with exceptionally low C/He ratios, have been subjected to a non-LTE abundance analysis using the tools TLUSTY and SYNSPEC. Defining atmospheric parameters were obtained from a grid of non-LTE atmospheres and a variety of spectroscopic indicators including He i and He ii line profiles, and the ionization equilibrium of ion pairs such as C ii/C iii and N ii/N iii. The various indicators provide a consistent set of atmospheric parameters: T {sub eff} = 25,000 ± 300 K, log g = 3.10 ± 0.12(cgs), and ξ = 13 ± 2 km s{sup −1} are provided for V652 Her, and T {sub eff} = 22,000 ± 600 K, log g = 3.45 ± 0.15 (cgs), and ξ = 10 km s{sup −1} are provided for HD 144941. In contrast to the non-LTE analyses, the LTE analyses—LTE atmospheres and an LTE line analysis—with the available indicators do not provide a consistent set of atmospheric parameters. The principal non-LTE effect on the elemental abundances is on the neon abundance. It is generally considered that these extreme helium stars with their very low C/He ratio result from the merger of two helium white dwarfs. Indeed, the derived composition of V652 Her is in excellent agreement with predictions by Zhang and Jeffery, who model the slow merger of helium white dwarfs; a slow merger results in the merged star having the composition of the accreted white dwarf. In the case of HD 144941, which appears to have evolved from metal-poor stars, a slow merger is incompatible with the observed composition but variations of the merger rate may account for the observed composition. More detailed theoretical studies of the merger of a pair of helium white dwarfs are to be encouraged.

“A magical little pill that will relieve you of your womanly issues”: What young women say about menstrual suppression

Science.gov (United States)

McMillan, Colleen; Jenkins, Amanda

2016-01-01

Perceptions of menstruation by media discourses portray this bodily function to be messy, inconvenient, and as an unnecessary phenomenon to be controlled or possibly eliminated. Commercials shown on YouTube targeted toward young women suggest that having a monthly period is not healthy and a lifestyle that is menses free is both pharmacologically available and recommended in order to live a fuller life. We explored the meanings attached to online menstrual suppression commercials with 10 women aged between 18 and 25. In-depth open-ended interviews were conducted over a 10-month period in 2014 after each participant viewed three menstrual suppression online advertisements. Feminist critical discourse was used for analysis with both authors coding for inter-rater reliability recognizing how our age difference and relationship as mother and daughter informed our interpretation. An overarching theme of tension emerged from the interviews with participants feeling detached due to the gendered stereotypes the commercials used to frame menstruation as compared to their own lived experience. Meanings associated with the menstrual suppression commercials were contrary to the participants’ lived experience of menstruation as a healthy process not a detrimental one to their well-being as suggested by the commercials. Subliminal messages within the advertisements were identified as reinforcing gender bias and prejudices, including those associated with femininity. Despite attempting to emulate popular culture, the menstrual suppression advertisements were largely dismissed by this group of participants as undermining their intelligence and of intentionally creating divisive binaries between groups of women. This study suggests that historical bias and stereotypical prejudices were identified by this group of young women within the marketing of menstrual suppression products and, as such, were dismissed as inauthentic to the menstruation experience reflecting a form of

"A magical little pill that will relieve you of your womanly issues": What young women say about menstrual suppression.

Science.gov (United States)

McMillan, Colleen; Jenkins, Amanda

2016-01-01

Perceptions of menstruation by media discourses portray this bodily function to be messy, inconvenient, and as an unnecessary phenomenon to be controlled or possibly eliminated. Commercials shown on YouTube targeted toward young women suggest that having a monthly period is not healthy and a lifestyle that is menses free is both pharmacologically available and recommended in order to live a fuller life. We explored the meanings attached to online menstrual suppression commercials with 10 women aged between 18 and 25. In-depth open-ended interviews were conducted over a 10-month period in 2014 after each participant viewed three menstrual suppression online advertisements. Feminist critical discourse was used for analysis with both authors coding for inter-rater reliability recognizing how our age difference and relationship as mother and daughter informed our interpretation. An overarching theme of tension emerged from the interviews with participants feeling detached due to the gendered stereotypes the commercials used to frame menstruation as compared to their own lived experience. Meanings associated with the menstrual suppression commercials were contrary to the participants' lived experience of menstruation as a healthy process not a detrimental one to their well-being as suggested by the commercials. Subliminal messages within the advertisements were identified as reinforcing gender bias and prejudices, including those associated with femininity. Despite attempting to emulate popular culture, the menstrual suppression advertisements were largely dismissed by this group of participants as undermining their intelligence and of intentionally creating divisive binaries between groups of women. This study suggests that historical bias and stereotypical prejudices were identified by this group of young women within the marketing of menstrual suppression products and, as such, were dismissed as inauthentic to the menstruation experience reflecting a form of

“A magical little pill that will relieve you of your womanly issues”: What young women say about menstrual suppression

Directory of Open Access Journals (Sweden)

Colleen McMillan

2016-11-01

Full Text Available Perceptions of menstruation by media discourses portray this bodily function to be messy, inconvenient, and as an unnecessary phenomenon to be controlled or possibly eliminated. Commercials shown on YouTube targeted toward young women suggest that having a monthly period is not healthy and a lifestyle that is menses free is both pharmacologically available and recommended in order to live a fuller life. We explored the meanings attached to online menstrual suppression commercials with 10 women aged between 18 and 25. In-depth open-ended interviews were conducted over a 10-month period in 2014 after each participant viewed three menstrual suppression online advertisements. Feminist critical discourse was used for analysis with both authors coding for inter-rater reliability recognizing how our age difference and relationship as mother and daughter informed our interpretation. An overarching theme of tension emerged from the interviews with participants feeling detached due to the gendered stereotypes the commercials used to frame menstruation as compared to their own lived experience. Meanings associated with the menstrual suppression commercials were contrary to the participants’ lived experience of menstruation as a healthy process not a detrimental one to their well-being as suggested by the commercials. Subliminal messages within the advertisements were identified as reinforcing gender bias and prejudices, including those associated with femininity. Despite attempting to emulate popular culture, the menstrual suppression advertisements were largely dismissed by this group of participants as undermining their intelligence and of intentionally creating divisive binaries between groups of women. This study suggests that historical bias and stereotypical prejudices were identified by this group of young women within the marketing of menstrual suppression products and, as such, were dismissed as inauthentic to the menstruation experience

Consumption of key food groups during the postpartum period in low-income, non-Hispanic black mothers.

Science.gov (United States)

Kay, Melissa C; Wasser, Heather; Adair, Linda S; Thompson, Amanda L; Siega-Riz, Anna Maria; Suchindran, Chirayath M; Bentley, Margaret E

2017-10-01

The postpartum period can impact diet quality and subsequently place women at greater risk for overweight or obesity. This study examined consumption of key food groups during the first 2 years postpartum among low income, non-Hispanic black, first-time mothers. Data were from the Infant Care, Feeding and Risk of Obesity Study, a cohort of 217 mother-infant dyads, followed from 3 to 18 months postpartum, collected from 2003 to 2007. At each study visit (3, 6, 9, 12, and 18 months) 24-h dietary recalls were collected. Consumption levels were compared to those recommended from the 2010 Dietary Guidelines for Americans (DGAs) for each of the following food groups: fruits, vegetables, grains, whole grains, protein foods and dairy, as well as an estimated upper limit for sugar-sweetened beverage (SSB) consumption. At each time point, mothers met recommended intake levels for grains and protein foods only. In random-intercept logistic regression models, no demographic or household characteristics were associated with a likelihood of consuming recommended levels for any of the food groups according to the DGAs. Given the low intake of fruits, vegetables, whole grains and lean protein foods and high intake of SSBs and refined grains, interventions targeting women's diet during the postpartum period are warranted. Copyright © 2017 Elsevier Ltd. All rights reserved.

Changing BMI scores among Canadian Indigenous and non-Indigenous children, youth, and young adults: Untangling age, period, and cohort effects

Directory of Open Access Journals (Sweden)

Piotr Wilk

2017-04-01

Full Text Available The objective of this study was to examine age, period and cohort effects on BMI among Indigenous and non-Indigenous populations, using repeated cross-sectional survey data from the CCHS (2001 to 2014. Cross-classified random-effect two-level models were used to estimate fixed effects for age and its quadratic term (Level 1, and also to estimate random effects for time periods and birth cohorts (Level 2, while controlling for the effects of Level 1 control variables: sex, model of interview and response by proxy. Overall, the results support the hypothesis that age and period effects are primarily responsible for the current obesity epidemic. L’objectif de cette étude était d’examiner les effets de l’âge, de la période et de la cohorte sur l’IMC chez les populations autochtones et non autochtones, en utilisant des données d’enquêtes transversales répétées de l’ESCC (2001 à 2014. On a utilisé des modèles à deux niveaux à effets aléatoires croisés pour estimer les effets fixes pour l’âge et son terme quadratique (niveau 1, et également estimer les effets aléatoires pour les périodes et les cohortes de naissance (niveau 2, tout en contrôlant les effets du niveau 1 Variables de contrôle: sexe, modèle d’interview et réponse par procuration. Dans l’ensemble, les résultats confirment l’hypothèse selon laquelle les effets de l’âge et de la période sont les principaux responsables de l’épidémie actuelle d’obésité.

Numerical Analyses of Subsoil-structure Interaction in Original Non-commercial Software based on FEM

Science.gov (United States)

Cajka, R.; Vaskova, J.; Vasek, J.

2018-04-01

For decades attention has been paid to interaction of foundation structures and subsoil and development of interaction models. Given that analytical solutions of subsoil-structure interaction could be deduced only for some simple shapes of load, analytical solutions are increasingly being replaced by numerical solutions (eg. FEM – Finite element method). Numerical analyses provides greater possibilities for taking into account the real factors involved in the subsoil-structure interaction and was also used in this article. This makes it possible to design the foundation structures more efficiently and still reliably and securely. Currently there are several software that, can deal with the interaction of foundations and subsoil. It has been demonstrated that non-commercial software called MKPINTER (created by Cajka) provides appropriately results close to actual measured values. In MKPINTER software stress-strain analysis of elastic half-space by means of Gauss numerical integration and Jacobean of transformation is done. Input data for numerical analysis were observed by experimental loading test of concrete slab. The loading was performed using unique experimental equipment which was constructed in the area Faculty of Civil Engineering, VŠB-TU Ostrava. The purpose of this paper is to compare resulting deformation of the slab with values observed during experimental loading test.

月経の心的影響に関する一考察 -青年期女性の語りから-

OpenAIRE

千葉, 理未

2014-01-01

This paper discusses the psychic influences of menstruation through narratives of adolescent women. Every woman has to relate well to her own menstruation for about forty years, and menstruation often disturbs women's daily life. There are many studies on images of menstruation. Many of these studies use questionnaires, and they are thus very important. But in these studies, only conscious images are revealed. There may also be unconscious images about menstruation, for example, kegare and fe...

Non-localization and localization ROC analyses using clinically based scoring

Science.gov (United States)

Paquerault, Sophie; Samuelson, Frank W.; Myers, Kyle J.; Smith, Robert C.

2009-02-01

We are investigating the potential for differences in study conclusions when assessing the estimated impact of a computer-aided detection (CAD) system on readers' performance. The data utilized in this investigation were derived from a multi-reader multi-case observer study involving one hundred mammographic background images to which fixed-size and fixed-intensity Gaussian signals were added, generating a low- and high-intensity signal sets. The study setting allowed CAD assessment in two situations: when CAD sensitivity was 1) superior or 2) lower than the average reader. Seven readers were asked to review each set in the unaided and CAD-aided reading modes, mark and rate their findings. Using this data, we studied the effect on study conclusion of three clinically-based receiver operating characteristic (ROC) scoring definitions. These scoring definitions included both location-specific and non-location-specific rules. The results showed agreement in the estimated impact of CAD on the overall reader performance. In the study setting where CAD sensitivity is superior to the average reader, the mean difference in AUC between the CAD-aided read and unaided read was 0.049 (95%CIs: -0.027; 0.130) for the image scoring definition that is based on non-location-specific rules, and 0.104 (95%CIs: 0.036; 0.174) and 0.090 (95%CIs: 0.031; 0.155) for image scoring definitions that are based on location-specific rules. The increases in AUC were statistically significant for the location-specific scoring definitions. It was further observed that the variance on these estimates was reduced when using the location-specific scoring definitions compared to that using a non-location-specific scoring definition. In the study setting where CAD sensitivity is equivalent or lower than the average reader, the mean differences in AUC are slightly above 0.01 for all image scoring definitions. These increases in AUC were not statistical significant for any of the image scoring definitions

Especially for Women: Could Gluten be Causing Your Symptoms?

Science.gov (United States)

... loss during menstruation. Anemia is often an early symptom of celiac disease, resulting from the intestine’s inability to absorb iron ... Anxiety More common among women than men. Possible symptoms of celiac disease and non-celiac gluten sensitivity. Other Autoimmune Diseases ...

34 CFR 74.28 - Period of availability of funds.

Science.gov (United States)

2010-07-01

... INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Post-Award Requirements Financial and Program Management § 74.28 Period of availability of funds. Where a funding period is...

Expression and phylogenetic analyses reveal paralogous lineages of putatively classical and non-classical MHC-I genes in three sparrow species (Passer).

Science.gov (United States)

Drews, Anna; Strandh, Maria; Råberg, Lars; Westerdahl, Helena

2017-06-26

The Major Histocompatibility Complex (MHC) plays a central role in immunity and has been given considerable attention by evolutionary ecologists due to its associations with fitness-related traits. Songbirds have unusually high numbers of MHC class I (MHC-I) genes, but it is not known whether all are expressed and equally important for immune function. Classical MHC-I genes are highly expressed, polymorphic and present peptides to T-cells whereas non-classical MHC-I genes have lower expression, are more monomorphic and do not present peptides to T-cells. To get a better understanding of the highly duplicated MHC genes in songbirds, we studied gene expression in a phylogenetic framework in three species of sparrows (house sparrow, tree sparrow and Spanish sparrow), using high-throughput sequencing. We hypothesize that sparrows could have classical and non-classical genes, as previously indicated though never tested using gene expression. The phylogenetic analyses reveal two distinct types of MHC-I alleles among the three sparrow species, one with high and one with low level of polymorphism, thus resembling classical and non-classical genes, respectively. All individuals had both types of alleles, but there was copy number variation both within and among the sparrow species. However, the number of highly polymorphic alleles that were expressed did not vary between species, suggesting that the structural genomic variation is counterbalanced by conserved gene expression. Overall, 50% of the MHC-I alleles were expressed in sparrows. Expression of the highly polymorphic alleles was very variable, whereas the alleles with low polymorphism had uniformly low expression. Interestingly, within an individual only one or two alleles from the polymorphic genes were highly expressed, indicating that only a single copy of these is highly expressed. Taken together, the phylogenetic reconstruction and the analyses of expression suggest that sparrows have both classical and non

Non-invasive genetic censusing and monitoring of primate populations.

Science.gov (United States)

Arandjelovic, Mimi; Vigilant, Linda

2018-03-01

Knowing the density or abundance of primate populations is essential for their conservation management and contextualizing socio-demographic and behavioral observations. When direct counts of animals are not possible, genetic analysis of non-invasive samples collected from wildlife populations allows estimates of population size with higher accuracy and precision than is possible using indirect signs. Furthermore, in contrast to traditional indirect survey methods, prolonged or periodic genetic sampling across months or years enables inference of group membership, movement, dynamics, and some kin relationships. Data may also be used to estimate sex ratios, sex differences in dispersal distances, and detect gene flow among locations. Recent advances in capture-recapture models have further improved the precision of population estimates derived from non-invasive samples. Simulations using these methods have shown that the confidence interval of point estimates includes the true population size when assumptions of the models are met, and therefore this range of population size minima and maxima should be emphasized in population monitoring studies. Innovations such as the use of sniffer dogs or anti-poaching patrols for sample collection are important to ensure adequate sampling, and the expected development of efficient and cost-effective genotyping by sequencing methods for DNAs derived from non-invasive samples will automate and speed analyses. © 2018 Wiley Periodicals, Inc.

Peculiar Emission Line Generation from Ultra-Rapid Quasi-Periodic ...

Indian Academy of Sciences (India)

E. F. Borra

2017-06-19

Jun 19, 2017 ... Fourier transform analyses of spectra converted to fre- quency units. Following the theoretical work in Borra. (2010), a Fourier transform analysis of 2.5 million spec- tra from the Sloan Digital Sky Survey database was carried out to detect periodic modulations (Borra 2013). Periodic modulations were found ...

Cointegration Approach to Analysing Inflation in Croatia

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Lena Malešević-Perović

2009-06-01

Full Text Available The aim of this paper is to analyse the determinants of inflation in Croatia in the period 1994:6-2006:6. We use a cointegration approach and find that increases in wages positively influence inflation in the long-run. Furthermore, in the period from June 1994 onward, the depreciation of the currency also contributed to inflation. Money does not explain Croatian inflation. This irrelevance of the money supply is consistent with its endogeneity to exchange rate targeting, whereby the money supply is determined by developments in the foreign exchange market. The value of inflation in the previous period is also found to be significant, thus indicating some inflation inertia.

Steric sea level variability (1993-2010) in an ensemble of ocean reanalyses and objective analyses

Science.gov (United States)

Storto, Andrea; Masina, Simona; Balmaseda, Magdalena; Guinehut, Stéphanie; Xue, Yan; Szekely, Tanguy; Fukumori, Ichiro; Forget, Gael; Chang, You-Soon; Good, Simon A.; Köhl, Armin; Vernieres, Guillaume; Ferry, Nicolas; Peterson, K. Andrew; Behringer, David; Ishii, Masayoshi; Masuda, Shuhei; Fujii, Yosuke; Toyoda, Takahiro; Yin, Yonghong; Valdivieso, Maria; Barnier, Bernard; Boyer, Tim; Lee, Tony; Gourrion, Jérome; Wang, Ou; Heimback, Patrick; Rosati, Anthony; Kovach, Robin; Hernandez, Fabrice; Martin, Matthew J.; Kamachi, Masafumi; Kuragano, Tsurane; Mogensen, Kristian; Alves, Oscar; Haines, Keith; Wang, Xiaochun

2017-08-01

Quantifying the effect of the seawater density changes on sea level variability is of crucial importance for climate change studies, as the sea level cumulative rise can be regarded as both an important climate change indicator and a possible danger for human activities in coastal areas. In this work, as part of the Ocean Reanalysis Intercomparison Project, the global and regional steric sea level changes are estimated and compared from an ensemble of 16 ocean reanalyses and 4 objective analyses. These estimates are initially compared with a satellite-derived (altimetry minus gravimetry) dataset for a short period (2003-2010). The ensemble mean exhibits a significant high correlation at both global and regional scale, and the ensemble of ocean reanalyses outperforms that of objective analyses, in particular in the Southern Ocean. The reanalysis ensemble mean thus represents a valuable tool for further analyses, although large uncertainties remain for the inter-annual trends. Within the extended intercomparison period that spans the altimetry era (1993-2010), we find that the ensemble of reanalyses and objective analyses are in good agreement, and both detect a trend of the global steric sea level of 1.0 and 1.1 ± 0.05 mm/year, respectively. However, the spread among the products of the halosteric component trend exceeds the mean trend itself, questioning the reliability of its estimate. This is related to the scarcity of salinity observations before the Argo era. Furthermore, the impact of deep ocean layers is non-negligible on the steric sea level variability (22 and 12 % for the layers below 700 and 1500 m of depth, respectively), although the small deep ocean trends are not significant with respect to the products spread.

Effects of Head-Supported Devices on Female Aviators during Simulated Helicopter Missions

Science.gov (United States)

1998-05-01

Hence, the window between day 10-20 post menstruation is chosen to avoid the discomfort associated with the menses period. The effect of hormone levels...system at the slightest irregularity , a multiple shutdown switches located around the MARS facility and two close-to-activate safety shutdown switches

A non-asymptotic homogenization theory for periodic electromagnetic structures.

Science.gov (United States)

Tsukerman, Igor; Markel, Vadim A

2014-08-08

Homogenization of electromagnetic periodic composites is treated as a two-scale problem and solved by approximating the fields on both scales with eigenmodes that satisfy Maxwell's equations and boundary conditions as accurately as possible. Built into this homogenization methodology is an error indicator whose value characterizes the accuracy of homogenization. The proposed theory allows one to define not only bulk, but also position-dependent material parameters (e.g. in proximity to a physical boundary) and to quantify the trade-off between the accuracy of homogenization and its range of applicability to various illumination conditions.

Liquidity implications of a commitment period reserve at national and global levels

International Nuclear Information System (INIS)

Haites, Erik; Missfeldt, Fanny

2004-01-01

The Kyoto Protocol, if it enters into force, will establish international emissions trading for quota that can be used for compliance with Protocol commitments. Concern that the non-compliance regime might not be sufficient to deter overselling led to adoption of the commitment period reserve requirement. This paper analyses the commitment period reserve in terms of (a) the liquidity of the international emissions trading market, and (b) international liquidity for domestic emissions trading programs in Annex B countries. The liquidity of the international greenhouse gas emissions trading market is measured as the sum of the quota surplus to the reserve requirement of net seller countries divided by the average annual assigned amount of all Annex B Parties and by the BAU emissions of Annex B Parties. Both measures are calculated using both the average values across 500 projections of future emissions and the values that yield the lowest liquidity (lowest reserves, highest emissions). Even the lowest estimates indicate liquidity comparable to that of the existing emissions trading programs. In addition, the international liquidity for domestic emissions trading programs with the commitment period reserve is likely to be comparable to or better than that of existing emissions trading markets, even under conservative assumptions

Geochemical evidence on the source regions of Tibetan Plateau dusts during non-monsoon period in 2008/09

Science.gov (United States)

Li, C.; Kang, S.; Zhang, Q.; Gao, S.

2012-12-01

Geochemical characteristics, source regions and related transport patterns of dust over the Tibetan Plateau (TP) are still unclear. To address these issues, major (Na, Mg, Al, K and Ca), trace (e.g. Li, Cr, Ni, As, Cd, Cs, Pb and U) and rare earth elements of dust samples from five snow-pits over the TP and its fringe areas during the non-monsoon period in 2008/2009 were analyzed. The results indicate that rare earth element compositions of snow-pit dust are similar to those of the upper continental crust. Enrichment factors of all the elements of snow-pit dust are identical to those of the pollution elements (e.g. Cu and Ni) and elements like Li, As and Cs that are concentrated in surface soils. In contrast, concentrations of some typical pollution elements (e.g. Cr and Cd) of snow pit dust are lower than those of dusts derived from the Sahara Desert and the Thar Desert surrounding the TP. Additionally, the compositions of rare earth elements and high field strength elements (Hf, Zr and Nb) of snow-pit dust are also similar to those of surface soils and different from dusts of these two deserts. The combined evidence, including dust transport patterns around the TP, supports the conclusion that the TP itself is the main source region of snow-pit dusts of the inner TP. It is unlikely that those particle-bound pollutants are transported into the TP from outside sources during the non-monsoon period. Ratios of Ce/Sm against Eu/Sm for the snow-pit dust, fine dust from the Sahara desert (A), and ratios of Ce/Er against Eu/Er for the snow-pit dust, fine dust from the Thar Desert (B). Dust from Sahasa cannot penetrate into the TP and transport only along the Himalayas at south and the Tianshan at north due to their high elevation

Effects of training and detraining on the static and dynamic balance in elderly fallers and non-fallers: a pilot study.

Science.gov (United States)

Toulotte, Claire; Thevenon, Andre; Fabre, Claudine

2006-01-30

The aim of this study was to evaluate the effects of training based on static and dynamic balance in single and dual task conditions in order to analyse the effects of detraining on static and dynamic balance in healthy elderly fallers and non-fallers. A group of 16 subjects were trained: eight fallers aged 71.1 +/- 5.0 years and eight non-fallers aged 68.4 +/- 4.5 years. The subjects were evaluated 3 months before the training period, 2 days before the training period, 2 days after the end of the training period and 3 months after the training period. All subjects performed a unipedal test with eyes open and eyes closed. Gait parameters were analysed under single-task and dual motor-task conditions. This study demonstrated a loss of physical capacities over 3 months for stride time, single support time for fallers in both conditions. Physical training significantly improves static and dynamic balance under single and dual task conditions. Lastly, after 3 months of detraining, a loss of the physical training effects were measured for fallers and non-fallers on the different walking parameters in the two conditions and on the unipedal tests. The absence of stimulation before the trained period shows a negative effect of ageing on walking and falls whereas training permits an improvement in static balance and the pattern of walking under single and dual task conditions, which could be due to an increase in muscular strength and a better division of attention. On the other hand, 3 months of detraining inhibited the effects of training, which showed the speed of the decline caused by 'natural' ageing.

A numerical model for the determination of periodic solutions of pipes subjected to non-conservative loads

International Nuclear Information System (INIS)

Velloso, P.A.; Galeao, A.C.

1989-05-01

This paper deals with nonlinear vibrations of pipes subjected to non-conservative loads. Periodic solutions of these problems are determined using a variational approach based on Hamilton's Principle combined with a Fourier series expansion to describe the displacement field time dependence. A finite element model which utilizes Hemite's cubic interpolation for both axial and transversal displacement amplitudes is used. This model is applied to the problem of a pipe subjected to a tangential and a normal follower force. The numerical results obtained with this model are compared with the corespondent solutions determined using a total lagrangian description for the Principle of Virtual Work, coupled with Newmark's step-by-step integration procedure. It is shown that for small to moderate displacement amplitudes the one-term Fourier series approximation compares fairly well with the predicted solution. For large displacements as least a two-term approximation should be utilized [pt

Al-Qurû’ fi Al-Qur’an ‘Inda Al-Anbary fi Al-Adhdâd

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Raushani Azza

2018-03-01

Full Text Available This study examines about the term al-Qurû in the Qur’an. Al-Qurû is one of the most popular discussions among muslim scholars and mufasir, both in terms of language and fiqh. However, there is a bate among muslim scholar and mufasir about the meaning of al-Qurû. It’s because al-Qurû is one of the sentence of al-Adhdâd wich has two meaning, especially in the Qur’an, namely haid (menstruation and thahr. One of the most popular muslim scholar who concern in Qur’an and Arabic is al-Anbari with his book al-Adhdâd. Al-Anbari explains that Qurû has two meanings, First, al-Qurû in etymology is the form of Jama’ from aqra and qurû. Second, al-Qurû has a meaning of menstruation, thahr, or the period of iddah as a sign of being allowed to remarry after certain period of time.

Non-destructive and non-invasive analyses shed light on the realization technique of ancient polychrome prints

Science.gov (United States)

Striová, Jana; Coccolini, Gabriele; Micheli, Sara; Lofrumento, Cristiana; Galeotti, Monica; Cagnini, Andrea; Castellucci, Emilio Mario

2009-08-01

Five polychrome prints representing famous painters, such as Albrecht Dürer, were analyzed using a non-destructive and non-invasive methodology as required by the artwork typology. The diagnostic strategy includes X-ray fluorescence (XRF), reflectance micro-infrared (μFTIR) and micro-Raman (μRaman) spectroscopy. These prints were realized with a la poupée method that involves application of the polychrome inks on a single copper plate, before the printing process. A broad range of compounds (i.e., cinnabar, red lead, white lead, umber earth, hydrated calcium sulfate, calcium carbonate, amorphous carbon, and Prussian blue) was employed as chalcographic inks, using linseed oil as a binding medium. Gamboge was identified in the delicate finishing brush touches realized in watercolor.

Acute Phase Proteins and their Relation to Energy Metabolites in Dairy Cows during the Pre- and Postpartal Period

Directory of Open Access Journals (Sweden)

Gabriel Kováč

2009-01-01

Full Text Available The objective of this study was to evaluate the concentrations of selected acute phase proteins – haptoglobin (Hp and serum amyloid A (SAA, and selected variables of energy metabolism in blood serum of dairy cows during different stages of the pre- and postpartal period. The analyses were performed in dairy cows of the Slovak spotted breed and its crossbreeds (n = 57. The cows were divided into 9 groups according to the evaluated part of reproduction cycle – from 4 weeks before parturition to 10 weeks after parturition. Significant differences were found in mean Hp and SAA concentrations during the monitored period (P P P P P P P < 0.001. Moreover, significant correlations were found between Hp and non-esterified fatty acids, Hp and β-hydroxybutyrate, as well as between SAA and non-esterified fatty acids. Our results indicate that the acute phase response occurs in cows around parturition, and suggest that there are relationships between mediators of immune response and several indices of energy metabolism. Our results also suggest that in cows with higher concentrations of non-esterified fatty acids, indicating a certain degree of lipid mobilisation, higher values of acute phase proteins may be found.

Quantum periods of Calabi–Yau fourfolds

Energy Technology Data Exchange (ETDEWEB)

Gerhardus, Andreas, E-mail: gerhardus@th.physik.uni-bonn.de; Jockers, Hans, E-mail: jockers@uni-bonn.de

2016-12-15

In this work we study the quantum periods together with their Picard–Fuchs differential equations of Calabi–Yau fourfolds. In contrast to Calabi–Yau threefolds, we argue that the large volume points of Calabi–Yau fourfolds generically are regular singular points of the Picard–Fuchs operators of non-maximally unipotent monodromy. We demonstrate this property in explicit examples of Calabi–Yau fourfolds with a single Kähler modulus. For these examples we construct integral quantum periods and study their global properties in the quantum Kähler moduli space with the help of numerical analytic continuation techniques. Furthermore, we determine their genus zero Gromov–Witten invariants, their Klemm–Pandharipande meeting invariants, and their genus one BPS invariants. In our computations we emphasize the features attributed to the non-maximally unipotent monodromy property. For instance, it implies the existence of integral quantum periods that at large volume are purely worldsheet instanton generated. To verify our results, we also present intersection theory techniques to enumerate lines with a marked point on complete intersection Calabi–Yau fourfolds in Grassmannian varieties.

Demographic histories of adaptively diverged riparian and non-riparian species of Ainsliaea (Asteraceae) inferred from coalescent analyses using multiple nuclear loci.

Science.gov (United States)

Mitsui, Yuki; Setoguchi, Hiroaki

2012-12-28

Understanding demographic histories, such as divergence time, patterns of gene flow, and population size changes, in ecologically diverging lineages provide implications for the process and maintenance of population differentiation by ecological adaptation. This study addressed the demographic histories in two independently derived lineages of flood-resistant riparian plants and their non-riparian relatives [Ainsliaea linearis (riparian) and A. apiculata (non-riparian); A. oblonga (riparian) and A. macroclinidioides (non-riparian); Asteraceae] using an isolation-with-migration (IM) model based on variation at 10 nuclear DNA loci. The highest posterior probabilities of the divergence time parameters were estimated to be ca. 25,000 years ago for A. linearis and A. apiculata and ca. 9000 years ago for A. oblonga and A. macroclinidioides, although the confidence intervals of the parameters had broad ranges. The likelihood ratio tests detected evidence of historical gene flow between both riparian/non-riparian species pairs. The riparian populations showed lower levels of genetic diversity and a significant reduction in effective population sizes compared to the non-riparian populations and their ancestral populations. This study showed the recent origins of flood-resistant riparian plants, which are remarkable examples of plant ecological adaptation. The recent divergence and genetic signatures of historical gene flow among riparian/non-riparian species implied that they underwent morphological and ecological differentiation within short evolutionary timescales and have maintained their species boundaries in the face of gene flow. Comparative analyses of adaptive divergence in two sets of riparian/non-riparian lineages suggested that strong natural selection by flooding had frequently reduced the genetic diversity and size of riparian populations through genetic drift, possibly leading to fixation of adaptive traits in riparian populations. The two sets of riparian/non

Do Menstrual Hygiene Management Interventions Improve Education and Psychosocial Outcomes for Women and Girls in Low and Middle Income Countries? A Systematic Review.

Directory of Open Access Journals (Sweden)

Julie Hennegan

Full Text Available Unhygienic and ineffective menstrual hygiene management has been documented across low resource contexts and linked to negative consequences for women and girls.To summarise and critically appraise evidence for the effectiveness of menstruation management interventions in improving women and girls' education, work and psychosocial wellbeing in low and middle income countries.Structured systematic searches were conducted in peer-reviewed and grey literature to identify studies evaluating education and resource provision interventions for menstruation management. Individual and cluster randomised controlled trials were eligible for inclusion, as were non-randomised controlled trials. Study characteristics, outcomes and risk of bias were extracted using a piloted form. Risk of bias was independently assessed by two researchers.Eight studies described in ten citations were eligible for inclusion. Studies were highly heterogeneous in design and context. Six included assessment of education-only interventions, and three provided assessment of the provision of different types of sanitary products (menstrual cups, disposable sanitary pads, and reusable sanitary pads. A moderate but non-significant standardised mean difference was found for the two studies assessing the impact of sanitary pad provision on school attendance: 0.49 (95%CI -0.13, 1.11. Included studies were heterogeneous with considerable risk of bias. Trials of education interventions reported positive impacts on menstrual knowledge and practices, however, many studies failed to assess other relevant outcomes. No trials assessed or reported harms.There is insufficient evidence to establish the effectiveness of menstruation management interventions, although current results are promising. Eight trials have been conducted, but a high risk of bias was found and clinical heterogeneity precluded synthesis of most results. Whilst trials provided some indication of positive results, further

Do Menstrual Hygiene Management Interventions Improve Education and Psychosocial Outcomes for Women and Girls in Low and Middle Income Countries? A Systematic Review.

Science.gov (United States)

Hennegan, Julie; Montgomery, Paul

2016-01-01

Unhygienic and ineffective menstrual hygiene management has been documented across low resource contexts and linked to negative consequences for women and girls. To summarise and critically appraise evidence for the effectiveness of menstruation management interventions in improving women and girls' education, work and psychosocial wellbeing in low and middle income countries. Structured systematic searches were conducted in peer-reviewed and grey literature to identify studies evaluating education and resource provision interventions for menstruation management. Individual and cluster randomised controlled trials were eligible for inclusion, as were non-randomised controlled trials. Study characteristics, outcomes and risk of bias were extracted using a piloted form. Risk of bias was independently assessed by two researchers. Eight studies described in ten citations were eligible for inclusion. Studies were highly heterogeneous in design and context. Six included assessment of education-only interventions, and three provided assessment of the provision of different types of sanitary products (menstrual cups, disposable sanitary pads, and reusable sanitary pads). A moderate but non-significant standardised mean difference was found for the two studies assessing the impact of sanitary pad provision on school attendance: 0.49 (95%CI -0.13, 1.11). Included studies were heterogeneous with considerable risk of bias. Trials of education interventions reported positive impacts on menstrual knowledge and practices, however, many studies failed to assess other relevant outcomes. No trials assessed or reported harms. There is insufficient evidence to establish the effectiveness of menstruation management interventions, although current results are promising. Eight trials have been conducted, but a high risk of bias was found and clinical heterogeneity precluded synthesis of most results. Whilst trials provided some indication of positive results, further research is needed

Time-periodic solutions of the Benjamin-Ono equation

Energy Technology Data Exchange (ETDEWEB)

Ambrose , D.M.; Wilkening, Jon

2008-04-01

We present a spectrally accurate numerical method for finding non-trivial time-periodic solutions of non-linear partial differential equations. The method is based on minimizing a functional (of the initial condition and the period) that is positive unless the solution is periodic, in which case it is zero. We solve an adjoint PDE to compute the gradient of this functional with respect to the initial condition. We include additional terms in the functional to specify the free parameters, which, in the case of the Benjamin-Ono equation, are the mean, a spatial phase, a temporal phase and the real part of one of the Fourier modes at t = 0. We use our method to study global paths of non-trivial time-periodic solutions connecting stationary and traveling waves of the Benjamin-Ono equation. As a starting guess for each path, we compute periodic solutions of the linearized problem by solving an infinite dimensional eigenvalue problem in closed form. We then use our numerical method to continue these solutions beyond the realm of linear theory until another traveling wave is reached (or until the solution blows up). By experimentation with data fitting, we identify the analytical form of the solutions on the path connecting the one-hump stationary solution to the two-hump traveling wave. We then derive exact formulas for these solutions by explicitly solving the system of ODE's governing the evolution of solitons using the ansatz suggested by the numerical simulations.

Time-periodic solutions of the Benjamin-Ono equation

International Nuclear Information System (INIS)

Ambrose, D.M.; Wilkening, Jon

2008-01-01

We present a spectrally accurate numerical method for finding non-trivial time-periodic solutions of non-linear partial differential equations. The method is based on minimizing a functional (of the initial condition and the period) that is positive unless the solution is periodic, in which case it is zero. We solve an adjoint PDE to compute the gradient of this functional with respect to the initial condition. We include additional terms in the functional to specify the free parameters, which, in the case of the Benjamin-Ono equation, are the mean, a spatial phase, a temporal phase and the real part of one of the Fourier modes at t = 0. We use our method to study global paths of non-trivial time-periodic solutions connecting stationary and traveling waves of the Benjamin-Ono equation. As a starting guess for each path, we compute periodic solutions of the linearized problem by solving an infinite dimensional eigenvalue problem in closed form. We then use our numerical method to continue these solutions beyond the realm of linear theory until another traveling wave is reached (or until the solution blows up). By experimentation with data fitting, we identify the analytical form of the solutions on the path connecting the one-hump stationary solution to the two-hump traveling wave. We then derive exact formulas for these solutions by explicitly solving the system of ODE's governing the evolution of solitons using the ansatz suggested by the numerical simulations

Human event-related brain potentials to auditory periodic noise stimuli.

Science.gov (United States)

Kaernbach, C; Schröger, E; Gunter, T C

1998-02-06

Periodic noise is perceived as different from ordinary non-repeating noise due to the involvement of echoic memory. Since this stimulus does not contain simple physical cues (such as onsets or spectral shape) that might obscure sensory memory interpretations, it is a valuable tool to study sensory memory functions. We demonstrated for the first time that the processing of periodic noise can be tapped by event-related brain potentials (ERPs). Human subjects received repeating segments of noise embedded in non-repeating noise. They were instructed to detect the periodicity inherent to the stimulation. We observed a central negativity time-locked on the periodic segment that correlated to the subjects behavioral performance in periodicity detection. It is argued that the ERP result indicates an enhancement of sensory-specific processing.

Impacts of Return-to-Work Type and Period on Job Retention in Workers with Occupational Injuries and Diseases.

Science.gov (United States)

Jeong, Inchul; Park, Jae Bum; Kim, Hyoung Ryoul; Yoon, Jin Ha; Won, Jong Uk; Roh, Jaehoon

2018-01-01

Despite the necessity of job retention in achieving return-to-work (RTW) goals, many workers leave their jobs after returning to work. The objective of this study was to examine the impacts of RTW type and period on job retention in Korean workers with occupational injuries and diseases. Data were derived from the Panel Study of Worker's Compensation Insurance, including data from 2,000 systemically sampled workers who had finished recuperation in 2012; three waves of survey data were included in the analyses. Workers who returned to work (n = 1,610) were included in the analysis of the relationship between RTW type and job retention, and 664 workers who returned to their original workplaces were included in the analysis of the relationship between RTW period and job retention. The participants completed a questionnaire, and administrative data were provided by workers' compensation insurance. A Cox proportional-hazards regression analysis showed an increased hazard ratio (HR) for non-retention of 2.66 (95% confidence interval, 2.11-3.35) in reemployed workers compared to that in workers returning to their original workplaces. Among workers returning to their original workplaces, HRs for non-retention were increased in workers with a RTW period of 13-24 months (3.03 [1.52-6.04]) and > 24 months (5.33 [2.14-13.25]) compared to workers with a RTW period of ≤ 3 months. RTW type and period were significantly related to job retention, suggesting that policies for promoting job retention rate should be implemented. © 2018 The Korean Academy of Medical Sciences.

Predictors of success of external cephalic version and cephalic presentation at birth among 1253 women with non-cephalic presentation using logistic regression and classification tree analyses.

Science.gov (United States)

Hutton, Eileen K; Simioni, Julia C; Thabane, Lehana

2017-08-01

Among women with a fetus with a non-cephalic presentation, external cephalic version (ECV) has been shown to reduce the rate of breech presentation at birth and cesarean birth. Compared with ECV at term, beginning ECV prior to 37 weeks' gestation decreases the number of infants in a non-cephalic presentation at birth. The purpose of this secondary analysis was to investigate factors associated with a successful ECV procedure and to present this in a clinically useful format. Data were collected as part of the Early ECV Pilot and Early ECV2 Trials, which randomized 1776 women with a fetus in breech presentation to either early ECV (34-36 weeks' gestation) or delayed ECV (at or after 37 weeks). The outcome of interest was successful ECV, defined as the fetus being in a cephalic presentation immediately following the procedure, as well as at the time of birth. The importance of several factors in predicting successful ECV was investigated using two statistical methods: logistic regression and classification and regression tree (CART) analyses. Among nulliparas, non-engagement of the presenting part and an easily palpable fetal head were independently associated with success. Among multiparas, non-engagement of the presenting part, gestation less than 37 weeks and an easily palpable fetal head were found to be independent predictors of success. These findings were consistent with results of the CART analyses. Regardless of parity, descent of the presenting part was the most discriminating factor in predicting successful ECV and cephalic presentation at birth. © 2017 Nordic Federation of Societies of Obstetrics and Gynecology.

Random-effects linear modeling and sample size tables for two special crossover designs of average bioequivalence studies: the four-period, two-sequence, two-formulation and six-period, three-sequence, three-formulation designs.

Science.gov (United States)

Diaz, Francisco J; Berg, Michel J; Krebill, Ron; Welty, Timothy; Gidal, Barry E; Alloway, Rita; Privitera, Michael

2013-12-01

Due to concern and debate in the epilepsy medical community and to the current interest of the US Food and Drug Administration (FDA) in revising approaches to the approval of generic drugs, the FDA is currently supporting ongoing bioequivalence studies of antiepileptic drugs, the EQUIGEN studies. During the design of these crossover studies, the researchers could not find commercial or non-commercial statistical software that quickly allowed computation of sample sizes for their designs, particularly software implementing the FDA requirement of using random-effects linear models for the analyses of bioequivalence studies. This article presents tables for sample-size evaluations of average bioequivalence studies based on the two crossover designs used in the EQUIGEN studies: the four-period, two-sequence, two-formulation design, and the six-period, three-sequence, three-formulation design. Sample-size computations assume that random-effects linear models are used in bioequivalence analyses with crossover designs. Random-effects linear models have been traditionally viewed by many pharmacologists and clinical researchers as just mathematical devices to analyze repeated-measures data. In contrast, a modern view of these models attributes an important mathematical role in theoretical formulations in personalized medicine to them, because these models not only have parameters that represent average patients, but also have parameters that represent individual patients. Moreover, the notation and language of random-effects linear models have evolved over the years. Thus, another goal of this article is to provide a presentation of the statistical modeling of data from bioequivalence studies that highlights the modern view of these models, with special emphasis on power analyses and sample-size computations.

An overview of industrial radiography accidents in India during the period 1987-1997

International Nuclear Information System (INIS)

Kumar, A.; Subramanya, M.J.; Raghavendran, C.P.; Murthy, B.K.S.; Vishwakarma, R.R.; Kannan, R.; Sharma, A.; Bhatt, B.C.

1998-01-01

Use of gamma radiation sources for non-destructive testing of welds, castings and vital components in several industries in India has recorded a steep rise in the last three decades. There are over 1000 industrial gamma radiography exposure devices (IGRED) in over 400 institutions in the country. Most of these employ Co-60 and Ir-192 gamma sources. In spite of regulatory control and procedures there have been accidents with the IGREDs resulting in significant radiation exposures and in some cases, injuries to members of public and radiography personnel. This paper analyses the accidents which occurred in India during the ten year period of 1987-1997, management of such accidents, steps taken to avoid recurrence of these accidents based on the lessons learnt. (author)

Simulating suppressed and active convection periods during TOGA COARE

CSIR Research Space (South Africa)

Bopape, Mary-Jane M

2013-09-01

Full Text Available The two-dimensional Non-hydrostatic s-coordinate Model (NSM) is used to simulate two twelve day periods and an eight day period observed during the Tropical Oceans Global Atmosphere Coupled Ocean-Atmosphere Response Experiment (TOGA COARE...

Cost Benefit Analyses of Developing a Legislation to Attract Non-Resident High Net Worth Individuals to Use Estonian Private Foundation Platform

Directory of Open Access Journals (Sweden)

Urmas Kaarlep

2017-05-01

Full Text Available On a global level, the high net worth population is expanding, and the wealth of high net worth individuals (HNWI is increasing rapidly. For various reasons, high net worth families and individuals are searching for vehicles to assist them in safeguarding and conveniently managing their wealth. Private foundations represent one useful avenue for achieving this end, and the use of private foundations has become increasingly popular in recent years, particularly in European countries. Many countries have laws which regulate private foundations and several are looking for adjusting or introducing legislation. In this article, authors analysing benefits for a country like Estonia in case the country increases the attractiveness of its jurisdiction for non-residents who are looking for establishment of a private foundation. The article comes to the conclusion that to be competitive, a country cannot collect tax revenues from private foundations established by non-residents except from income originated in the very same country. However, the country can earn benefits from revenues received by companies rendering services to non-residents and their private foundations. The article demonstrates that service fees a country earns and taxes collected from these fees would be substantial enough to make necessary changes to legislation beneficial for a country.

Analysis of the width-w non-adjacent form in conjunction with hyperelliptic curve cryptography and with lattices☆

Science.gov (United States)

Krenn, Daniel

2013-01-01

In this work the number of occurrences of a fixed non-zero digit in the width-w non-adjacent forms of all elements of a lattice in some region (e.g. a ball) is analysed. As bases, expanding endomorphisms with eigenvalues of the same absolute value are allowed. Applications of the main result are on numeral systems with an algebraic integer as base. Those come from efficient scalar multiplication methods (Frobenius-and-add methods) in hyperelliptic curves cryptography, and the result is needed for analysing the running time of such algorithms. The counting result itself is an asymptotic formula, where its main term coincides with the full block length analysis. In its second order term a periodic fluctuation is exhibited. The proof follows Delange’s method. PMID:23805020

The pharmacological and non-pharmacological treatment of attention deficit hyperactivity disorder in children and adolescents: A systematic review with network meta-analyses of randomised trials.

Directory of Open Access Journals (Sweden)

Ferrán Catalá-López

Full Text Available Attention deficit hyperactivity disorder (ADHD is one of the most commonly diagnosed psychiatric disorders in childhood. A wide variety of treatments have been used for the management of ADHD. We aimed to compare the efficacy and safety of pharmacological, psychological and complementary and alternative medicine interventions for the treatment of ADHD in children and adolescents.We performed a systematic review with network meta-analyses. Randomised controlled trials (≥ 3 weeks follow-up were identified from published and unpublished sources through searches in PubMed and the Cochrane Library (up to April 7, 2016. Interventions of interest were pharmacological (stimulants, non-stimulants, antidepressants, antipsychotics, and other unlicensed drugs, psychological (behavioural, cognitive training and neurofeedback and complementary and alternative medicine (dietary therapy, fatty acids, amino acids, minerals, herbal therapy, homeopathy, and physical activity. The primary outcomes were efficacy (treatment response and acceptability (all-cause discontinuation. Secondary outcomes included discontinuation due to adverse events (tolerability, as well as serious adverse events and specific adverse events. Random-effects Bayesian network meta-analyses were conducted to obtain estimates as odds ratios (ORs with 95% credibility intervals. We analysed interventions by class and individually. 190 randomised trials (52 different interventions grouped in 32 therapeutic classes that enrolled 26114 participants with ADHD were included in complex networks. At the class level, behavioural therapy (alone or in combination with stimulants, stimulants, and non-stimulant seemed significantly more efficacious than placebo. Behavioural therapy in combination with stimulants seemed superior to stimulants or non-stimulants. Stimulants seemed superior to behavioural therapy, cognitive training and non-stimulants. Behavioural therapy, stimulants and their combination

Comparison of fundamental natural period of masonry and reinforced concrete buildings retrieved from experimental campaigns performed in Italy, Greece and Spain

Science.gov (United States)

Nigro, Antonella; Ponzo, Felice C.; Ditommaso, Rocco; Auletta, Gianluca; Iacovino, Chiara; Nigro, Domenico S.; Soupios, Pantelis; García-Fernández, Mariano; Jimenez, Maria-Jose

2017-04-01

Aim of this study is the experimental estimation of the dynamic characteristics of existing buildings and the comparison of the related fundamental natural period of the buildings (masonry and reinforced concrete) located in Basilicata (Italy), in Madrid (Spain) and in Crete (Greece). Several experimental campaigns, on different kind of structures all over the world, have been performed in the last years with the aim of proposing simplified relationships to evaluate the fundamental period of buildings. Most of formulas retrieved from experimental analyses provide vibration periods smaller than those suggested by the Italian Seismic Code (NTC2008) and the European Seismic Code (EC8). It is known that the fundamental period of a structure play a key role in the correct estimation of the spectral acceleration for seismic static analyses and to detect possible resonance phenomena with the foundation soil. Usually, simplified approaches dictate the use of safety factors greater than those related to in depth dynamic linear and nonlinear analyses with the aim to cover any unexpected uncertainties. The fundamental period calculated with the simplified formula given by both NTC 2008 and EC8 is higher than the fundamental period measured on the investigated structures in Italy, Spain and Greece. The consequence is that the spectral acceleration adopted in the seismic static analysis may be significantly different than real spectral acceleration. This approach could produces a decreasing in safety factors obtained using linear seismic static analyses. Based on numerical and experimental results, in order to confirm the results proposed in this work, authors suggest to increase the number of numerical and experimental tests considering also the effects of non-structural components and soil during small, medium and strong motion earthquakes. Acknowledgements This study was partially funded by the Italian Department of Civil Protection within the project DPC-RELUIS 2016 - RS4

An interview study analysing patients' experiences and perceptions of non-laxative or full-laxative preparation with faecal tagging prior to CT colonography

International Nuclear Information System (INIS)

Ghanouni, A.; Smith, S.G.; Halligan, S.; Taylor, S.A.; Plumb, A.; Boone, D.; Wagner, C. von

2013-01-01

Aim: To compare patients' experiences of either non- or full-laxative bowel preparation with additional faecal tagging and subsequent computed tomographic (CT) colonography using in-depth interviews to elicit detailed responses. Materials and methods: Patients who received CT colonography after non- (n = 9) or full-laxative (n = 9) preparation participated in a semi-structured telephone interview at least 2 days after the investigation. Full-laxative preparation consisted of magnesium citrate and sodium picosulphate administered at home (or polyethylene glycol, if contraindicated), followed by hospital-based faecal tagging with iohexol. Non-laxative preparation was home-based barium sulphate for faecal tagging. Interviews were transcribed and thematically analysed to identify recurrent themes on patients' perceptions and experiences. Results: Experiences of full-laxative preparation were usually negative and characterized by pre-test diarrhoea that caused significant interference with daily routine. Post-test flatus was common. Non-laxative preparation was well-tolerated; patients reported no or minimal changes to bowel habit and rapid return to daily routine. Patients reported worry and uncertainty about the purpose of faecal tagging. For iohexol, this also added burden from waiting before testing. Conclusion: Patients' responses supported previous findings that non-laxative preparation is more acceptable than full-laxative preparation but both can be improved. Faecal tagging used in combination with laxative preparation is poorly understood, adding burden and worry. Home-based non-laxative preparation is also poorly understood and patients require better information on the purpose and mechanism in order to give fully informed consent. This may also optimize adherence to instructions. Allowing home-based self-administration of all types of preparation would prevent waiting before testing

Trends in mouth cancer incidence in Mumbai, India (1995-2009): An age-period-cohort analysis.

Science.gov (United States)

Shridhar, Krithiga; Rajaraman, Preetha; Koyande, Shravani; Parikh, Purvish M; Chaturvedi, Pankaj; Dhillon, Preet K; Dikshit, Rajesh P

2016-06-01

Despite tobacco control and health promotion efforts, the incidence rates of mouth cancer are increasing across most regions in India. Analysing the influence of age, time period and birth cohort on these secular trends can point towards underlying factors and help identify high-risk populations for improved cancer control programmes. We evaluated secular changes in mouth cancer incidence among men and women aged 25-74 years in Mumbai between 1995 and 2009 by calculating age-specific and age-standardized incidence rates (ASR). We estimated the age-adjusted linear trend for annual percent change (EAPC) using the drift parameter, and conducted an age-period-cohort (APC) analysis to quantify recent time trends and to evaluate the significance of birth cohort and calendar period effects. Over the 15-year period, age-standardized incidence rates of mouth cancer in men in Mumbai increased by 2.7% annually (95% CI:1.9 to 3.4), pMumbai cancer registry indicate a significant linear increase of mouth cancer incidence from 1995 to 2009 in men, which was driven by younger men aged 25-49 years, and a non-significant upward trend in similarly aged younger women. Health promotion efforts should more effectively target younger cohorts. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

Pesticide Residues, Results from the period 2004-2011

DEFF Research Database (Denmark)

Petersen, Annette; Jensen, Bodil Hamborg; Andersen, Jens Hinge

The present report presents the results from the 2004-2011 period of the monitoring programmes conducted by The Danish Veterinary and Food Administration. The programmes included commodities of fruit, vegetable, cereals and animal origin using random sampling from food on the Danish market. Since...... the beginning of the 1960, Denmark has monitored fruit and vegetables for pesticides residues. For the periods 1993-1997 and 1998-2003, results were collated and the dietary exposure was calculated. In this report data for the analyses carried out in the period 2004-2011 are reported as well as the exposure...

An Exploration of Mothers' Attitudes towards Their Daughters' Menarche

Science.gov (United States)

Bennett, Clare; Harden, Jane

2014-01-01

Menarche is a significant milestone for young women, representing an important juncture between girlhood and maturation. The limited literature that exists suggests that a mother's reaction to her daughter's first periods can shape her experiences and perceptions of menstruation which, in turn, may impact on her self-image and, consequently,…

Vitamin C, Vitamin E, L-Arginine, Low dose, HbSS, Free radicals ...

African Journals Online (AJOL)

Backgroumd: Sexual disorders have been extensively studied in diabetic men while possible changes in the sexual function of diabetic women have only recently received attention. Mammals other than primates do not menstruate, thus their sexual cycle is termed “Estrous cycle”. The period of 'heat' (estrus), is the time of ...

Gingival recession in smokers and non-smokers with minimal periodontal disease.

Science.gov (United States)

Müller, Hans-Peter; Stadermann, Sabine; Heinecke, Achim

2002-02-01

Smoking is a major risk factor for destructive periodontal disease. There is limited information with regard to effects of smoking in subjects with minimal periodontal destruction. The aim of the present investigation was to assess the development of gingival recession in young adult smokers and non-smokers. 61 systemically healthy young adults, 19 to 30 years of age completed the final examination. 30 volunteers smoked at least 20 cigarettes per day, whereas 31 subjects were non-smokers. Clinical periodontal conditions were assessed 4x within a time period of 6 months. Site-specific analyses considering the correlated structure of data were performed. At the outset, 50% of subjects presented with gingival recession at 1 or more sites. There was no significant difference in the prevalence of gingival recession between non-smokers and smokers. Severe recession in excess of 2 mm affected about 23% non-smokers but only 7% smokers. Some further gingival recession developed during the 6-month observation period. In a multivariate logistic regression analysis, the risk for recession development appeared not to be influenced by smoking status after adjusting for periodontal probing depth, recession at baseline, tooth brushing frequency, gender, jaw, tooth type and site. Present data did not support the hypothesis that smokers are at an increased risk for the development of gingival recession.

[Characteristics and sources of particulate polycyclic aromatic hydrocarbons (PAHs) during haze period in Guangzhou].

Science.gov (United States)

Duan, Jing-Chun; Tan, Ji-Hua; Sheng, Guo-Ying; Fu, Jia-Mo

2009-06-15

PM10 (particulates matter with aerodynamic diameter Guangzhou city between March 2002 and June 2003. Polycyclic aromatic hydrocarbons (PAHs) were studied during haze and non-haze periods in both summer and winter. PAHs pollution was serious in haze period compared with that in non-haze period, especially in winter. Compared with non-haze period, Phe, Ant, Flu, Pyr, BaA, Chr, IcdP, DahA and BghiP were more abundant in haze period in summer, and BaF, BeP, BaP, Pery, IcdP, DahA and BghiP were more abundant in haze period in winter. The BEQ values were 3.5 ng x m(-3), 3.35 ng x m(-3), 1.43 ng x m(-3) and 13.0 ng x m(-3) in non-haze in summer, in haze in summer, in non-haze in winter and in haze in winter, respectively. The BEQ values in non-haze in summer, in haze in summer and in non-haze in winter in Guangzhou (average: 2.76 ng x m(-3)) were relatively low in Chinese cities, and comparable with oversea cities. However, the BEQ value in haze in winter was relatively high in Chinese cities. It indicated that haze in winter would impair human health seriously. The diagnostic ratios suggested gasoline and diesel vehicle emission were main sources of PAHs in summer, and diesel vehicle and coal combustion emission were main sources of PAHs in winter; PAHs may come from both local sources and long-range transportation in non-haze in winter.

38 CFR 49.28 - Period of availability of funds.

Science.gov (United States)

2010-07-01

... (CONTINUED) UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Post-Award Requirements Financial and Program Management § 49.28 Period of availability of funds. Where a funding period is specified, a recipient may...

40 CFR 30.28 - Period of availability of funds.

Science.gov (United States)

2010-07-01

... ASSISTANCE UNIFORM ADMINISTRATIVE REQUIREMENTS FOR GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Post-Award Requirements Financial and Program Management § 30.28 Period of availability of funds. Where a funding period is specified, a recipient may...

Monostable traveling waves for a time-periodic and delayed nonlocal reaction-diffusion equation

Science.gov (United States)

Li, Panxiao; Wu, Shi-Liang

2018-04-01

This paper is concerned with a time-periodic and delayed nonlocal reaction-diffusion population model with monostable nonlinearity. Under quasi-monotone or non-quasi-monotone assumptions, it is known that there exists a critical wave speed c_*>0 such that a periodic traveling wave exists if and only if the wave speed is above c_*. In this paper, we first prove the uniqueness of non-critical periodic traveling waves regardless of whether the model is quasi-monotone or not. Further, in the quasi-monotone case, we establish the exponential stability of non-critical periodic traveling fronts. Finally, we illustrate the main results by discussing two types of death and birth functions arising from population biology.

Increases in soil water content after the mortality of non-native trees in oceanic island forest ecosystems are due to reduced water loss during dry periods.

Science.gov (United States)

Hata, Kenji; Kawakami, Kazuto; Kachi, Naoki

2016-03-01

The control of dominant, non-native trees can alter the water balance of soils in forest ecosystems via hydrological processes, which results in changes in soil water environments. To test this idea, we evaluated the effects of the mortality of an invasive tree, Casuarina equisetifolia Forst., on the water content of surface soils on the Ogasawara Islands, subtropical islands in the northwestern Pacific Ocean, using a manipulative herbicide experiment. Temporal changes in volumetric water content of surface soils at 6 cm depth at sites where all trees of C. equisetifolia were killed by herbicide were compared with those of adjacent control sites before and after their mortality with consideration of the amount of precipitation. In addition, the rate of decrease in the soil water content during dry periods and the rate of increase in the soil water content during rainfall periods were compared between herbicide and control sites. Soil water content at sites treated with herbicide was significantly higher after treatment than soil water content at control sites during the same period. Differences between initial and minimum values of soil water content at the herbicide sites during the drying events were significantly lower than the corresponding differences in the control quadrats. During rainfall periods, both initial and maximum values of soil water contents in the herbicided quadrats were higher, and differences between the maximum and initial values did not differ between the herbicided and control quadrats. Our results indicated that the mortality of non-native trees from forest ecosystems increased water content of surface soils, due primarily to a slower rate of decrease in soil water content during dry periods. Copyright © 2015 Elsevier B.V. All rights reserved.

Pulse electrochemical machining on Invar alloy: Optical microscopic/SEM and non-contact 3D measurement study of surface analyses

International Nuclear Information System (INIS)

Kim, S.H.; Choi, S.G.; Choi, W.K.; Yang, B.Y.; Lee, E.S.

2014-01-01

Highlights: • Invar alloy was electrochemically polished and then subjected to PECM (Pulse Electro Chemical Machining) in a mixture of NaCl, glycerin, and distilled water. • Optical microscopic/SEM and non-contact 3D measurement study of Invar surface analyses. • Analysis result shows that applied voltage and electrode shape are factors that affect the surface conditions. - Abstract: In this study, Invar alloy (Fe 63.5%, Ni 36.5%) was electrochemically polished by PECM (Pulse Electro Chemical Machining) in a mixture of NaCl, glycerin, and distilled water. A series of PECM experiments were carried out with different voltages and different electrode shapes, and then the surfaces of polished Invar alloy were investigated. The polished Invar alloy surfaces were investigated by optical microscope, scanning electron microscope (SEM), and non-contact 3D measurement (white light microscopes) and it was found that different applied voltages produced different surface characteristics on the Invar alloy surface because of the locally concentrated applied voltage on the Invar alloy surface. Moreover, we found that the shapes of electrode also have an effect on the surface characteristics on Invar alloy surface by influencing the applied voltage. These experimental findings provide fundamental knowledge for PECM of Invar alloy by surface analysis

Knowledge and attitudes of female university students on menstrual cycle and contraception.

Science.gov (United States)

Szűcs, Márta; Bitó, Tamás; Csíkos, Csaba; Párducz Szöllősi, Andrea; Furau, Cristian; Blidaru, Iolanda; Kapamadzija, Aleksandra; Sedlecky, Katarina; Bártfai, György

2017-02-01

Socioeconomic changes, as well as the development of new contraceptive modalities may influence women's preferences in the selection of a method of contraception. The aim of this study was to evaluate the knowledge, opinions and attitudes of female university students regarding the menstrual cycle, sexual health and contraception. A questionnaire-based survey was conducted among 2572 female university students in Hungary, Romania and Serbia, between November 2009 and January 2011. A higher proportion of students of health sciences than students of other faculties had appropriate knowledge of the fertile period within a menstrual cycle: 86.0%, 71.5% (p = .02) and 61.1% vs. 71.9% (p students believed in the need for monthly menstruation in order to be healthy; however, merely 30 to 40% of them wished to have monthly bleeding. In general, the respondents were aware of the importance of menstruation in relation to sexual health; however, they wished to suppress the menstruation-related symptoms. Differences in the knowledge and attitudes of female university students of the three assessed countries may be explained in part by cultural differences, and in part by the nature of their studies.

Reliability of Serum Metabolites over a Two-Year Period: A Targeted Metabolomic Approach in Fasting and Non-Fasting Samples from EPIC

Science.gov (United States)

Achaintre, David; Sacerdote, Carlotta; Vineis, Paolo; Key, Timothy J.; Onland Moret, N. Charlotte; Scalbert, Augustin; Rinaldi, Sabina; Ferrari, Pietro

2015-01-01

Objective Although metabolic profiles have been associated with chronic disease risk, lack of temporal stability of metabolite levels could limit their use in epidemiological investigations. The present study aims to evaluate the reliability over a two-year period of 158 metabolites and compare reliability over time in fasting and non-fasting serum samples. Methods Metabolites were measured with the AbsolueIDQp180 kit (Biocrates, Innsbruck, Austria) by mass spectrometry and included acylcarnitines, amino acids, biogenic amines, hexoses, phosphatidylcholines and sphingomyelins. Measurements were performed on repeat serum samples collected two years apart in 27 fasting men from Turin, Italy, and 39 non-fasting women from Utrecht, The Netherlands, all participating in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Reproducibility was assessed by estimating intraclass correlation coefficients (ICCs) in multivariable mixed models. Results In fasting samples, a median ICC of 0.70 was observed. ICC values were fasting samples, the median ICC was 0.54. ICC values were fasting as compared to fasting samples, with a statistically significant difference for 19–36% of acylcarnitines, phosphatidylcholines and sphingomyelins. Conclusion A single measurement per individual may be sufficient for the study of 73% and 52% of the metabolites showing ICCs >0.50 in fasting and non-fasting samples, respectively. ICCs were higher in fasting samples that are preferable to non-fasting. PMID:26274920

Internal crisis in a second-order non-linear non-autonomous electronic oscillator

International Nuclear Information System (INIS)

Stavrinides, S.G.; Deliolanis, N.C.; Miliou, A.N.; Laopoulos, Th.; Anagnostopoulos, A.N.

2008-01-01

The internal crisis of a second-order non-linear non-autonomous chaotic electronic circuit is studied. The phase portraits consist of two interacting sub-attractors, a chaotic and a periodic one. Maximal Lyapunov exponents were calculated, for both the periodic and the chaotic waveforms, in order to confirm their nature. Transitions between the chaotic and the periodic sub-attractors become more frequent by increasing the circuit driving frequency. The frequency distribution of the corresponding laminar lengths and their average values indicate that an internal crisis takes place in this circuit, manifested in the intermittent behaviour of the corresponding orbits

Bone mineral density in midlife women: the Study of Women's Health in Qatar.

Science.gov (United States)

Gerber, L M; Bener, A; Al-Ali, H M; Hammoudeh, M; Liu, L Q; Verjee, M

2015-04-01

The aim of this study is to investigate bone mineral density (BMD) for a large cross-section of midlife Arab women living in Qatar and to evaluate the association of body mass index (BMI), menopause status, and nationality, on BMD of the spine and femur. A cross-sectional study was conducted among women aged 40-60 years recruited from nine primary-care health centers in Qatar. BMD (g/m(2)) was assessed at the lumbar spine and the femur. The combined prevalence of osteopenia and osteoporosis was 4% at the femur and 16.2% at the spine. BMI and menstrual status were both independently associated with BMD at the spine and at the femur (all p values < 0.001). As BMI increased, BMD increased at both the spine and femur. Women who menstruated in the past 12 months had 0.82 g/cm(2) and 0.61 g/cm(2) greater BMD at the spine and femur, respectively, compared with women who had not menstruated in 12 months. Nationality was not associated with mean BMD of the spine or the femur. No significant differences were observed between Qatari and non-Qatari women in terms of mean BMD values at the spine and the femur except for the femur in the age group 55-60, where values were lower among non-Qataris (p = 0.04). Multivariable analyses showed that BMI and menstrual status were found to be strongly associated with BMD levels at the spine and femur. The high prevalence of obesity observed in this sample may explain the low levels of osteopenia and osteoporosis observed.

Cancer incidence among Mormons and non-Mormons in Utah (United States) 1995-1999.

Science.gov (United States)

Merrill, Ray M; Lyon, Joseph L

2005-05-01

Population-based Utah Cancer Registry data were linked with Latter-day Saint (LDS or Mormon) Church membership records to obtain site-specific cancer incidence for LDS and non-LDS populations in Utah during 1995-1999. Analyses were based on 27,631 incident cases of cancer identified among whites. Restriction to whites was made because of the small number of nonwhites, approximately 5%, in the state during the study period. The direct method was used to age-adjust the rates to the 2000 U.S. standard population. Significantly lower cancer incidence rates per 100,000 were observed among LDS compared with non-LDS males (287.2 vs. 321.1) and females (247.7 vs. 341.0). The lower rates are primarily explained by smoking-related cancers and female breast cancer. If the overall cancer incidence rate in LDS had occurred in the non-LDS population, 2.9% or 421 fewer cases would have occurred among males and 7.9% or 1,025 fewer cases would have occurred among females during the study period. Given our current knowledge of risk factors for cancer, differences between LDS and non-LDS in smoking for males and smoking and sexual and reproductive behaviors in females primarily explain the lower risk of cancer in LDS populations.

22 CFR 145.28 - Period of availability of funds.

Science.gov (United States)

2010-04-01

... 145.28 Foreign Relations DEPARTMENT OF STATE CIVIL RIGHTS GRANTS AND AGREEMENTS WITH INSTITUTIONS OF HIGHER EDUCATION, HOSPITALS, AND OTHER NON-PROFIT ORGANIZATIONS Post-Award Requirements Financial and Program Management § 145.28 Period of availability of funds. Where a funding period is specified, a...

Frictional systems under periodic loads — History-dependence, non-uniqueness and energy dissipation

International Nuclear Information System (INIS)

Barber, J R

2012-01-01

Nominally static contacts such as bolted or shrink-fit joints typically experience regions of microslip when subjected to oscillatory loading. This results in energy dissipation, reflected as apparent hysteretic damping of the system, and also may cause the initiation of fretting fatigue cracks. Early theoretical studies of the Hertzian contact problem by Cattaneo and Mindlin were confirmed experimentally by Johnson, who identified signs of fretting damage in the slip annulus predicted by the theory. For many years, tribologists assumed that Melan's theorem in plasticity could be extended to frictional systems — i.e. that if there exists a state of residual stress associated with frictional slip that is sufficient to prevent periodic slip in the steady state, then the system will shake down, regardless of the initial condition. However, we now know that this is true only if there is no coupling between the normal and tangential loading problems, as will be the case notably when contact occurs on a symmetry plane. For all other cases, periodic loading scenarios can be devised such that shakedown occurs for some initial conditions and not for others. The initial condition here might be determined by the assembly protocol — e.g. the order in which a set of bolts is tightened — or by the exact loading path before the steady cycle is attained. This non-uniqueness of the steady state persists at load amplitudes above the shakedown limit, in which case there is always some dissipation, but the dissipation per cycle (and hence both the effective damping and the susceptibility to fretting damage) depends on the initial conditions. This implies that fretting fatigue experiments need to follow a well-defined assembly protocol if reproducible results are to be obtained. We shall also present results showing that when both normal and tangential forces vary in time, the energy dissipation is very sensitive to the relative phase of the oscillatory components, being greatest

Policy Uncertainty, Investment and Commitment Periods

Energy Technology Data Exchange (ETDEWEB)

NONE

2007-07-01