WorldWideScience

Sample records for non-medical direct oop

  1. Teaching OOP with Financial Literacy

    Science.gov (United States)

    Zhu, Hongwei

    2011-01-01

    Students lose interest in learning programming when the materials are not related to their lives. A challenge facing most students is that they lack the financial literacy necessary to manage their debts. An approach is developed to integrate financial literacy into an object-oriented programming (OOP) course. The approach is effective in…

  2. OOPS, Turning MIT Opencourseware into Chinese: An analysis of a community of practice of global translators

    Directory of Open Access Journals (Sweden)

    Mimi Miyoung Lee

    2007-11-01

    Full Text Available An all-volunteer organization called the Opensource Opencourseware Prototype System (OOPS, headquartered in Taiwan, was initially designed to translate open source materials from MIT OpenCourseWare (OCW site into Chinese. Given the recent plethora of open educational resources (OER, such as the OCW, the growing use of such resources by the world community, and the emergence of online global education communities to localize resources such as the OOPS, a key goal of this research was to understand how the OOPS members negotiate meanings and form a collective identity in this cross-continent online community. To help with our explorations and analyses within the OOPS translation community, several core principles from Etienne Wenger’s concept of Communities of Practice (COP guided our analyses, including mutual engagement, joint enterprise, shared repertoire, reification, and overall identity of the community. In this paper, we detail how each of these key components was uniquely manifested within the OOPS. Three issues appeared central to the emergence, success, and challenges of the community such as OOPS: 1 strong, stable, and fairly democratic leadership; 2 participation incentives; and 3 online storytelling or opportunities to share one’s translation successes, struggles, and advice within an asynchronous discussion forum. While an extremely high level of enthusiasm among the OOPS members underpinned the success of the OOPS, discussion continues on issues related to quality control, purpose and scope, and forms of legitimate participation. This study, therefore, provides an initial window into the emergence and functioning of an online global education COP in the OER movement. Future research directions related to online global educational communities are discussed.

  3. From Procedural to Object-Oriented Programming (OOP- Performance in OOP: An empirical study

    Directory of Open Access Journals (Sweden)

    Irene Govender

    2011-02-01

    Full Text Available This exploratory study of introductory pre- and in-service teachers’ performance in object-oriented programming (OOP assessments reveals important issues with regard to learning and teaching OOP, using java. The study is set against the backdrop of the country’s transition of its national IT curriculum from a procedural to an object-oriented programming language. The effect of prior programming experience and performances in different types of questions are examined. A combination of quantitative and qualitative methods is used to analyse the data. The effect of prior programming experience of a procedural kind and the type of assessments given is shown to have a marked influence on the performance in programming assessments and teaching of OOP. Many introductory OOP courses are in effect taught procedurally as courses in the small. Therefore educating teachers how to teach programming is a significant educational challenge. Some implications for teaching are therefore suggested

  4. Inheritance and Synchronization in Concurrent OOP

    Science.gov (United States)

    Briot, Jean-Pierre; Yonezawa, Akinori

    This paper discusses knowledge sharing (inheritance) mechanisms for Object-Oriented Programming (OOP) in the context of concurrent (distributed) languages. We review three different schemes: inheritance, delegation and copy. A fourth model, called recipe-query, is presented and all are compared and criticized. Techniques relying on the shared memory assumption are rejected. We point out the conflict between distributing knowledge among objects and the synchronization of concurrent objects.

  5. State of art and key problems of OOP for FE programming in engineering analysis

    Science.gov (United States)

    Li, Heng; Zhou, Yunyun

    2013-03-01

    Object-oriented programming (OOP) has been the most important development method, especially for huge and complicated program systems, since OOP can overcome structural complexity of code, strong coupling among modules and poor maintenance shortcomings in traditional structural programming. Since B.W.R.Forde applied OOP to Finite Element (FE) firstly in 1990, the research in this field has not been stopped. Scholars have taken many positive and useful attempts on study of OOP in FE programming from different aspects. The state of the art of OOP in FE and current development has been reviewed, and the key problems in the OOP FEM fields thus are pointed out, thus prospects of OOP in FE code design are put forward.

  6. An OOP Approach to Simplify MDI Application Development An OOP Approach to Simplify MDI Application Development

    Directory of Open Access Journals (Sweden)

    Donato Hernández Fusilier

    2012-02-01

    Full Text Available The Multiple Document Interface (MDI is a Microsoft Windows specification that allows managing multiple documents using a single graphic interface application. An MDI application allows opening several documents simultaneously. Only one document is active at a particular time. MDI applications can be deployed using Win32 or Microsoft Foundation Classes (MFC. Programs developed using Win32 are faster than those using MFC. However, Win32applications are difficult to implement and prone to errors. It should be mentioned that, learning how to properly use MFC to deploy MDI applications is not simple, and performance is typically worse than that of Win32 applications. A method to simplify the development of MDI applications using Object-Oriented Programming (OOP is proposed. Subsequently, it is shown that this method generates compact code that is easier to read and maintain than other methods (i.e., MFC. Finally, it is demonstrated that the proposed method allowsthe rapid development of MDI applications without sacrificing application performance.La Interfase para Múltiples Documentos (MDI es una especificación del sistema operativo Microsoft Windows que permite manipular varios documentos usando un sólo programa. Un programa del tipo MDI permite abrir varios documentos simultáneamente. En un instante dado, sólo un documento es activo. Los programas del tipo MDI pueden desarrollarseu sando Win32 o las clases fundamentales de Microsoft (MFC. Los programas desarrollados usando Win32 son más rápidos que los programas que usan MFC. Sin embargo, éstos son difíciles de implementar promoviendo la existencia de errores. Cabe mencionar que el desarrollo de programas del tipo MDI usando MFC no es sencillo, y que su desempeño estípicamente peor que el de un programa del tipo Win32. Se propone un método que drásticamente simplifica el desarrollo de programas del tipo MDI por medio de la Programación Orientada a Objetos (POO. Se demuestra que el m

  7. A Long-Term Investigation of the Comprehension of OOP Concepts by Novices

    Science.gov (United States)

    Ragonis, Noa; Ben-Ari, Mordechai

    2005-01-01

    This article describes research on the learning of object-oriented programming (OOP) by novices. During two academic years, we taught OOP to high school students, using Java and BlueJ. Our approach to teaching featured: objects-first, teaching composed classes relatively early, deferring the teaching of main methods, and focusing on class…

  8. Virtual testing of driver OOP scenarios: effect of modeling detail on injury response

    NARCIS (Netherlands)

    Bosch-Rekveldt, M.G.C.; Hoof, J.F.A.M. van

    2004-01-01

    This study investigates the relevance of certain parameters for virtual testing of the driver's side OOP problem and attempts to answer the following questions: Which level of detail is needed in the airbag models to assess occupants' injury values for OOP scenarios? What is the influence of the air

  9. A long-term investigation of the comprehension of OOP concepts by novices

    Science.gov (United States)

    Ragonis, Noa; Ben-Ari, Mordechai

    2005-09-01

    This article describes research on the learning of object-oriented programming (OOP) by novices. During two academic years, we taught OOP to high school students, using Java and BlueJ. Our approach to teaching featured: objects-first, teaching composed classes relatively early, deferring the teaching of main methods, and focusing on class structure before algorithms. The research used a constructivist qualitative research methodology using observations and field notes, audio and video recordings, and an analysis of artifacts such as homework assignments. The findings were divided into four primary categories: class vs. object, instantiation and constructors, simple vs. composed classes, and program flow. In total, 58 conceptions and difficulties were identified. Nevertheless, at the end of the courses, the students understood the basic principles of OOP. The two main contributions of this research are: (i) the breadth and depth of its investigation into the concepts held by novices studying OOP, and (ii) the nature of the constructivist qualitative research methodology.

  10. Object Oriented Programming Systems (OOPS) and frame representations: An investigation of programming paradigms

    Science.gov (United States)

    Auty, David

    1988-01-01

    The project was initiated to research Object Oriented Programming Systems (OOPS) and frame representation systems, their significance and applicability, and their implementation in or relationship to Ada. Object orientated is currently a very popular conceptual adjective. Object oriented programming, in particular, is promoted as a particularly productive approach to programming; an approach which maximizes opportunities for code reuse and lends itself to the definition of convenient and well-developed units. Such units are thus expected to be usable in a variety of situations, beyond the typical highly specific unit development of other approaches. Frame represenation systems share a common heritage and similar conceptual foundations. Together they represent a quickly emerging alternative approach to programming. The approach is to first define the terms, starting with relevant concepts and using these to put bounds on what is meant by OOPS and Frames. From this the possibilities were pursued to merge OOPS with Ada which will further elucidate the significant characteristics which make up this programming approach. Finally, some of the merits and demerits of OOPS were briefly considered as a way of addressing the applicability of OOPS to various programming tasks.

  11. Non-medical use of methylphenidate: a review

    OpenAIRE

    Freese, Luana; Signor,Luciana; Machado,Cassio; Ferigolo, Maristela; Barros,Helena Maria Tannhauser

    2012-01-01

    INTRODUCTION: Methylphenidate is a psychostimulant medication used for the treatment of attention deficit hyperactivity disorder and narcolepsy. However, it has also been used for non-medical purposes, e.g. to produce euphoria, to increase self-esteem, and to achieve the so-called neurocognitive enhancement, decreasing the feeling of tiredness and increasing focus and attention. OBJECTIVE: To describe, from theoretical and contextual points of view, the potential for abuse and non-medical use...

  12. Conceptual OOP design of Pilot Code for Two-Fluid, Three-field Model with C++ 6.0

    Energy Technology Data Exchange (ETDEWEB)

    Chung, B. D.; Lee, Y. J

    2006-09-15

    To establish the concept of the objective oriented program (OOP) design for reactor safety analysis code, the preliminary OOP design for PILOT code, which based on one dimensional two fluid three filed model, has been attempted with C++ language feature. Microsoft C++ language has been used since it is available as groupware utilization in KAERI. The language has can be merged with Compac Visual Fortran 6.6 in Visual Studio platform. In the development platform, C++ has been used as main language and Fortran has been used as mixed language in connection with C++ main drive program. The mixed language environment is a specific feature provided in visual studio. Existing Fortran source was utilized for input routine of reading steam table from generated file and routine of steam property calculation. The calling convention and passing argument from C++ driver was corrected. The mathematical routine, such as inverse matrix conversion and tridiagonal matrix solver, has been used as PILOT Fortran routines. Simple volume and junction utilized in PILOT code can be treated as objects, since they are the basic construction elements of code system. Other routines for overall solution scheme have been realized as procedure C functions. The conceptual design which consists of hydraulic loop, component, volume, and junction class has been described in the appendix in order to give the essential OOP structure of system safety analysis code. The attempt shows that many part of system analysis code can be expressed as objects, although the overall structure should be maintained as procedure functions. The encapsulation of data and functions within an object can provide many beneficial aspects in programming of system code.

  13. Non-Medical Management of Raynaud’s Disease,

    Science.gov (United States)

    1981-06-29

    I AD-AIll 032 ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MA F/B &/ S I NON-MEDICAL MANAGEMENT OF RAYNAUD’S OISEASE,(U) I JUN 81 J B JOBE. J B...collagen disease, they are referred to as Rana d’s phenomenon or syndrome . Minimal criteria for diagnosis of Raynaud’s disease have long been established...JAMA. l945; 129:1-- s . 2. blain, A 1l1, Coiler, FA, Carver, 6i. Raynaud’s disease: A study ot criteria for prognosis. Surgery. 19)1; 2V:387-31)7. 3

  14. [Non-medical applications for brain MRI: Ethical considerations].

    Science.gov (United States)

    Sarrazin, S; Fagot-Largeault, A; Leboyer, M; Houenou, J

    2015-04-01

    The recent neuroimaging techniques offer the possibility to better understand complex cognitive processes that are involved in mental disorders and thus have become cornerstone tools for research in psychiatry. The performances of functional magnetic resonance imaging are not limited to medical research and are used in non-medical fields. These recent applications represent new challenges for bioethics. In this article we aim at discussing the new ethical issues raised by the applications of the latest neuroimaging technologies to non-medical fields. We included a selection of peer-reviewed English medical articles after a search on NCBI Pubmed database and Google scholar from 2000 to 2013. We screened bibliographical tables for supplementary references. Websites of governmental French institutions implicated in ethical questions were also screened for governmental reports. Findings of brain areas supporting emotional responses and regulation have been used for marketing research, also called neuromarketing. The discovery of different brain activation patterns in antisocial disorder has led to changes in forensic psychiatry with the use of imaging techniques with unproven validity. Automated classification algorithms and multivariate statistical analyses of brain images have been applied to brain-reading techniques, aiming at predicting unconscious neural processes in humans. We finally report the current position of the French legislation recently revised and discuss the technical limits of such techniques. In the near future, brain imaging could find clinical applications in psychiatry as diagnostic or predictive tools. However, the latest advances in brain imaging are also used in non-scientific fields raising key ethical questions. Involvement of neuroscientists, psychiatrists, physicians but also of citizens in neuroethics discussions is crucial to challenge the risk of unregulated uses of brain imaging. Copyright © 2014 L’Encéphale, Paris. Published by

  15. Longitudinal trajectories of non-medical use of prescription medication among middle and high school students

    Science.gov (United States)

    Boyd, Carol J.; Cranford, James A.; McCabe, Sean Esteban

    2016-01-01

    The non-medical use of prescription medications has been identified as a major public health problem among youth, although few longitudinal studies have examined non-medical use of prescription medications in the context of other drug use. Previous cross-sectional studies have shown gender and race differences in non-medical use of prescription medications. It was hypothesized that (1) non-medical use of prescription medications increases with age, and (2) these increases will be stronger in magnitude among female and Caucasian adolescents. Changes in non-medical use of prescription medications across 4 years were examined and compared with changes in other drug use (e.g., alcohol and marijuana). Middle and high school students enrolled in 5 schools in southeastern Michigan completed web-based surveys at 4 annual time points. The cumulative sample size was 5,217. The sample ranged from 12 to 18 years, 61% were Caucasian, 34% were African American, and 50% were female. Using a series of repeated measures latent class analyses, the trajectories of non-medical use of prescription medications were examined, demonstrating a 2-class solution: (1) the no/low non-medical use of prescription medications group had low probabilities of any non-medical use of prescription medications across all grades, and (2) the any non-medical use of prescription medications group showed a roughly linear increase in the probability of non-medical use of prescription medications over time. The probability of any non-medical use of prescription medications increased during the transition from middle school to high school. Results from this longitudinal study yielded several noteworthy findings: Participants who were classified in the any/high non-medical use of prescription medications group showed a discontinuous pattern of non-medical use of prescription medications over time, indicating that non-medical use of prescription medications is a relatively sporadic behavior that does not persist

  16. DevOops Redux

    CERN Document Server

    CERN. Geneva; Johnson, Ken

    2017-01-01

    DevOps toolchains are transforming Modern IT, but hackers can undermine their benefits through poorly implemented or vulnerable DevOps tools. Chris Gates and Ken Johnson will share their collaborative attack research into the technology driving DevOps. They will share an attacker?s perspective on exploiting DevOps organizations and the countermeasures these organizations should employ. About the speakers Ken Johnson, CTO of nVisium, has been hacking web applications professionally for 8 years. Ken is both a breaker and builder and currently leads the nVisium product team. Previously, Ken has spoken at DerbyCon, AppSec USA, AppSec DC, AppSec California, DevOpsDays DC, LASCON, RubyNation, and numerous Ruby, OWASP, and AWS events. Ken is currently investing his time between OWASP’s Railsgoat, Elxir and Go, as well as all aspects of AWS offerings. Chris Gates has extensive experience in network and web application penetration testing, Red Teaming and Purple Teaming. Chris is currently learning to be ...

  17. Causes of non-medication-induced nasogastric tube occlusion.

    Science.gov (United States)

    Hofstetter, J; Allen, L V

    1992-03-01

    In vitro simulation of nasogastric tube delivery of enteral formulas was used to study the mechanism and prevention of non-medication-induced nasogastric tube occlusion. Enteral nutrition products--Osmolite, Ensure, Vital High Nitrogen, and Vivonex T.E.N.--were placed in glass beakers and titrated with hydrochloric acid to determine the pH at which clotting would occur. Factors such as pH, protein content, viscosity, electrolyte composition, flow rate, and tube design were evaluated to determine their effects on coagulation of formula. Addition of simethicone emulsion and docusate sodium to the formulas and siliconization of the nasogastric tubes were studies for their effect on prevention of clog formation. Clumping began to occur at pH 4.6 (the isoelectric point for casein) for Ensure and Osmolite; addition of protein supplement did not change the pH at which coagulation occurred. Vital High Nitrogen and Vivonex T.E.N. formulations did not clump in the beakers. Ensure and Osmolite coagulated within 35 seconds at pH 4.6 or less and remained unchanged at pH greater than 6.0. Addition of sodium or calcium caseinate greatly increased the tendency of the formulas to coagulate. Viscosity of the formula increased markedly as pH decreased. Addition of electrolytes had no effect on precipitation or clumping. Slow or no flow rates within nasogastric tubes placed in simulated gastric juice decreased the pH and caused clumping of formulas within the tubes in a retrograde manner. Flow time or clog formation was not affected by the addition of simethicone or docusate sodium or siliconization of the nasogastric tube.(ABSTRACT TRUNCATED AT 250 WORDS)

  18. Caesarean section for non-medical reasons at term.

    Science.gov (United States)

    Lavender, Tina; Hofmeyr, G Justus; Neilson, James P; Kingdon, Carol; Gyte, Gillian M L

    2012-03-14

    controlled trials, upon which to base any practice recommendations regarding planned caesarean section for non-medical reasons at term. In the absence of trial data, there is an urgent need for a systematic review of observational studies and a synthesis of qualitative data to better assess the short- and long-term effects of caesarean section and vaginal birth.

  19. Non-medical triggers of patients' contacts to general practitioners

    DEFF Research Database (Denmark)

    Eriksson, Tina

    family practice, general practice, primary health care, health care services, health behaviour, mass media, reasons for encounter, case-crossover, time-selection bias, recall bias, bi-directional study......family practice, general practice, primary health care, health care services, health behaviour, mass media, reasons for encounter, case-crossover, time-selection bias, recall bias, bi-directional study...

  20. How medical services mask provision of non-medical supportive care in palliative oncology ?

    OpenAIRE

    Buthion, Valérie; Moumjid, Nora; Margier, Jennifer

    2015-01-01

    OBJECTIVES In the context of cancer, non-medical supportive care improves quality of life. While policymakers expect it to be cheaper than high-tech medical care, we hypothesized that it is in fact embedded in and camouflaged by hospital medical services. METHODS In a cross-sectional descriptive study, we conducted qualitative interviews with healthcare providers, patients and family caregivers in France. We first performed a functional analysis to identify non-medical supportive care functio...

  1. Conceptual Design of Object Oriented Program (OOP) for Pilot Code of Two-Fluid, Three-field Model with C++ 6.0

    Energy Technology Data Exchange (ETDEWEB)

    Chung, Bub Dong; Lee, Young Jin [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    2006-07-01

    Engineering software for design purpose in nuclear industries have been developed since early 1970s, and well established in 1980s. The most popular and common language for the software development has been FORTRAN series, until the more sophisticated GUI and software coupling is needed. The advanced computer language, such as C++, C has been developed to help the programming for the easy GUI need and reuse of well developed routines, with adopting the objective oriented program. A recent trend of programming becomes objective-oriented since the results are often more intuitive and easier to maintain than procedure program. The main motivation of this work is to capture objective oriented concepts for conventional safety analysis programs which consist of many functions and procedure oriented structures. In this work, the new objective programming with C++ 6.0 language has been tried for the PILOT code written in FORTRAN language, and conceptual OOP design of the system safety analysis code has been done.

  2. [Delegation of medical responsibilities to non-medical personnel. Options and limits from a legal viewpoint].

    Science.gov (United States)

    Ulsenheimer, K

    2009-11-01

    Increasing specialization and growing mechanization in medicine have strongly supported the transfer of originally medical responsibilities to non-medical personnel. The enormous pressure of costs as a result of limited financial resources in the health system make the delegation of previously medical functions to cheaper non-medical ancillary staff expedient and the sometimes obvious lack of physicians also gains importance by the delegation of many activities away from medical staff. In the German health system there is no legal norm which clearly and definitively describes the field of activity of a medical doctor. Fundamental for a reform of the areas of responsibility between physicians and non-medical personnel is a terminological differentiation between instruction-dependent, subordinate, non-independent assistance and the delegation of medical responsibilities which are transferred to non-medical personnel for independent and self-determined completion under the supervision and control of a physician. The inclination towards risk of medical activities, the need of protection of the patient and the intellectual prerequisites required for carrying out the necessary measures define the limitations for the delegation of medical responsibilities to non-medical ancillary staff. These criteria demarcate by expert assessment the exclusively medical field of activity in a sufficiently exact and convincing manner.

  3. Legalization of marijuana for non-medical use: health, policy, socioeconomic, and nursing implications.

    Science.gov (United States)

    Durkin, Anne

    2014-09-01

    The legalization of marijuana is a controversial issue with implications for health care providers, policy makers, and society at large. The use of marijuana for medical reasons is accepted in many states. However, legal sale of the drug for non-medical use began for the first time on January 1, 2014, in Colorado, following a relaxation of marijuana restrictions that is unprecedented worldwide. News reports have indicated that sales of the drug have been brisk. Marijuana-infused food products have been unexpectedly popular, exceeding sales projections. Marijuana use is associated with numerous physical and mental disorders and could result in addiction. Evidence suggests its potency has increased since the 1980s. Colorado has established regulations regarding the sale of marijuana for non-medical use, but concerns still exist. The current article offers a discussion of the health, public policy, socioeconomic, and nursing implications of the legalization of marijuana for non-medical use.

  4. Usage of emergency contraception between medical related and non-medical related students.

    LENUS (Irish Health Repository)

    Khalid, A K

    2009-04-01

    Teenagers and young adultshave the most risk of unplanned pregnancy, due to lack of awareness to see a family planning provider after unprotected sexual intercourse. In addition, nearly one in five physicians is reluctant to provide information regarding Emergency Contraception (EC) to women and this may contribute to their lack of awareness. This study was conducted to assess the knowledge, attitudes and practices regarding the use of EC between medical related students compared to non-medical related students. Data collection was done using questionnaires distributed among students in University College Cork (UCC). 93% of medically related students were aware of EC compared to only 73.5% of non-medically related students. Medical related students also were more aware about the mechanism of action and detailed knowledge of EC compared to the non-medical students. This study has proven that medically related students have more detailed knowledge regarding EC compared to non-medical related students. However, there was no significant difference noted regarding the attitude and practice between the two groups.

  5. An instrument for broadened risk assessment in antenatal health care including non-medical issues.

    NARCIS (Netherlands)

    A.A. Vos (Amber); M.J. van Veen (Mieke); E. Birnie (Erwin); S. Denktaş (Semiha); E.A.P. Steegers (Eric); G.J. Bonsel (Gouke)

    2015-01-01

    markdownabstractGrowing evidence on the risk contributing role of non-medical factors on pregnancy outcomes urged for a new approach in early antenatal risk selection. The evidence invites to more integration, in particular between the clinical working area and the public health domain. We developed

  6. Assessment and care for non-medical risk factors in current antenatal health care

    NARCIS (Netherlands)

    A.A. Vos (Amber); Leeman, A. (Annemiek); W. Waelput (Wim); G.J. Bonsel (Gouke); E.A.P. Steegers (Eric); S. Denktaş (Semiha)

    2015-01-01

    textabstractObjective: this study aims to identify current practice in risk assessment, current antenatal policy and referral possibilities for non-medical risk factors (lifestyle and social risk factors), and to explore the satisfaction among obstetric caregivers in their collaboration with

  7. An overiew of non medical prescribing across one strategic health authority: a questionnaire survey

    Directory of Open Access Journals (Sweden)

    Courtenay Molly

    2012-06-01

    Full Text Available Abstract Background Over 50,000 non-medical healthcare professionals across the United Kingdom now have prescribing capabilities. However, there is no evidence available with regards to the extent to which non-medical prescribing (NMP has been implemented within organisations across a strategic health authority (SHA. The aim of the study was to provide an overview of NMP across one SHA. Methods NMP leads across one SHA were asked to supply the email addresses of NMPs within their organisation. One thousand five hundred and eighty five NMPs were contacted and invited to complete an on-line descriptive questionnaire survey, 883 (55.7% participants responded. Data was collected between November 2010 and February 2011. Results The majority of NMPs were based in primary care and worked in a team of 2 or more. Nurse independent supplementary prescribers were the largest group (590 or 68.6% compared to community practitioner prescribers (198 or 22.4%, pharmacist independent supplementary prescribers (35 or 4%, and allied health professionals and optometrist independent and/or supplementary prescribers (8 or 0.9%. Nearly all (over 90% of nurse independent supplementary prescribers prescribed medicines. Approximately a third of pharmacist independent supplementary prescribers, allied health professionals, and community practitioner prescribers did not prescribe. Clinical governance procedures were largely in place, although fewer procedures were reported by community practitioner prescribers. General practice nurses prescribed the most items. Factors affecting prescribing practice were: employer, the level of experience prior to becoming a non-medical prescriber, existence of governance procedures and support for the prescribing role (p  Conclusion NMP in this strategic health authority reflects national development of this relatively new role in that the majority of non-medical prescribers were nurses based in primary care, with fewer pharmacist and

  8. Development of a Modified Korean East Asian Student Stress Inventory by Comparing Stress Levels in Medical Students with Those in Non-Medical Students.

    Science.gov (United States)

    Shin, Hee Kon; Kang, Seok Hoon; Lim, Sun-Hye; Yang, Jeong Hee; Chae, Sunguk

    2016-01-01

    Medical students are usually under more stress than that experienced by non-medical students. Stress testing tools for Korean medical students have not been sufficiently studied. Thus, we adapted and modified the East Asian Student Stress Inventory (EASSI), a stress testing tool for Korean students studying abroad, and verified its usefulness as a stress test in Korean university students. We also compared and analyzed stress levels between medical and non-medical students. A questionnaire survey was conducted on medical and non-medical students of a national university, and the responses of 224 students were analyzed for this study. Factor analysis and reliability testing were performed based on data collected for 25 adapted EASSI questions and those on the Korean version of the Global Assessment of Recent Stress Scale (GARSS). A correlation analysis was performed between the 13 modified EASSI questions and the GARSS, and validity of the modified EASSI was verified by directly comparing stress levels between the two student groups. The 13 questions adapted for the EASSI were called the modified EASSI and classified into four factors through a factor analysis and reliability testing. The Pearson's correlation analysis revealed a significant correlation between the modified EASSI and the Korean version of the GARSS, suggesting a complementary strategy of using both tests. The validity and reliability of the EASSI were verified. The modified Korean EASSI could be a useful stress test for Korean medical students. Our results show that medical students were under more stress than that of non-medical students. Thus, these results could be helpful for managing stress in medical students.

  9. The Berlin Brain–Computer Interface: Non-Medical Uses of BCI Technology

    Science.gov (United States)

    Blankertz, Benjamin; Tangermann, Michael; Vidaurre, Carmen; Fazli, Siamac; Sannelli, Claudia; Haufe, Stefan; Maeder, Cecilia; Ramsey, Lenny; Sturm, Irene; Curio, Gabriel; Müller, Klaus-Robert

    2010-01-01

    Brain–computer interfacing (BCI) is a steadily growing area of research. While initially BCI research was focused on applications for paralyzed patients, increasingly more alternative applications in healthy human subjects are proposed and investigated. In particular, monitoring of mental states and decoding of covert user states have seen a strong rise of interest. Here, we present some examples of such novel applications which provide evidence for the promising potential of BCI technology for non-medical uses. Furthermore, we discuss distinct methodological improvements required to bring non-medical applications of BCI technology to a diversity of layperson target groups, e.g., ease of use, minimal training, general usability, short control latencies. PMID:21165175

  10. The Association between Non-Medical Prescription Drug Use and Suicidal Behavior among United States Adolescents

    Directory of Open Access Journals (Sweden)

    Amanda L. Divin

    2014-11-01

    Full Text Available Adolescence represents a vulnerable time for the development of both drug use/abuse and mental illness. Although previous research has substantiated a relationship between drug use and suicidal behavior, little research has examined this relationship with non-medical prescription drug use. Given the growing prevalence of non-medical prescription drug use (NMPDU among adolescents, this study explored the association between NMPDU and suicidal behavior. Nationally representative data were derived from 16, 410 adolescents who completed the 2009 National Youth Risk Behavior Survey. Approximately 19.8% of participants reported lifetime NMPDU. NMPDU was associated with significantly increased odds of suicidal behavior (P < 0.01, with seriously considering attempting suicide and making a plan about attempting suicide representing the strongest correlates for males and females. Results suggest the importance of 1 continued reinforcement of drug education programs in high school begun at earlier ages and 2 mental health care and screenings among adolescents.

  11. Role of Religiosity in Psychological Well-Being Among Medical and Non-medical Students.

    Science.gov (United States)

    Saleem, Shemaila; Saleem, Tamkeen

    2016-12-27

    Religion has been generally considered as a protective factor for the psychological health of the people. As many studies have publicized a high prevalence of psychological morbidities among the medical students during their academic stages of medical schools, it is significant to investigate whether religiosity functions as a protective factor, to explore religiosity as a predictor of psychological well-being in a sample of medical students, and to compare the results of medical students as well as non-medical students with respect to religiosity and psychological well-being. The study is carried out in Federal Medical and Dental College and International Islamic University, Islamabad. The present study examined a sample of 120 medical students from Federal Medical and Dental College and 120 non-medical students from International Islamic University, Islamabad. Purposive sampling was used. The respondents completed religious orientation scale and scale of psychological well-being scale along with a demographic data sheet. In order to measure the study variables, linear regression and t test were used. The findings revealed that religiosity is a strong predictor of psychological well-being. Extrinsic and intrinsic religiosity predicts psychological well-being among the students. The results indicated a significant difference in psychological well-being between medical and non-medical students. No significant difference was found in religiosity of medical and non-medical students. The gender differences in religiosity and psychological well-being were found to be insignificant. The results emphasize that psychological well-being is prophesied by religiosity. The present research suggests further investigations and also endows with trends for psychological evaluation, development of religious beliefs, and interventions for augmenting psychological well-being among the medical students.

  12. An instrument for broadened risk assessment in antenatal health care including non-medical issues

    OpenAIRE

    Amber Amanda Vos; Mieke J van Veen; Erwin Birnie; Semiha Denktas; Eric AP Steegers; Bonsel, Gouke J

    2015-01-01

    Introduction: Growing evidence on the risk contributing role of non-medical factors on pregnancy outcomes urged for a new approach in early antenatal risk selection. The evidence invites to more integration, in particular between the clinical working area and the public health domain. We developed a non-invasive, standardized instrument for comprehensive antenatal risk assessment. The current study presents the application-oriented development of a risk screening instrument for early antenata...

  13. Non-medical aspects of civilian-military collaboration in management of major incidents.

    Science.gov (United States)

    Khorram-Manesh, A; Lönroth, H; Rotter, P; Wilhelmsson, M; Aremyr, J; Berner, A; Andersson, A Nero; Carlström, E

    2017-03-02

    Disasters and major incidents demand a multidisciplinary management. Recent experiences from terrorist attacks worldwide have resulted in a search for better assessment of the needs, resources, and knowledge in the medical and non-medical management of these incidents and also actualized the need for collaboration between civilian and military healthcare. The aim of this study was to evaluate the impact of the civilian-military collaboration in a Swedish context with the main focus on its non-medical management. An exercise, simulating a foreign military attack centrally on Swedish soil, was designed, initiated, and conducted by a team consisting of civilian and military staff. Data were collected prospectively and evaluated by an expert team. Specific practical and technical issues were presented in collaboration between civilian and military staffs. In addition, shortcomings in decision-making, follow-up, communication, and collaboration due to prominent lack of training and exercising the tasks and positions in all managerial levels of the hospital were identified. Current social and political unrests and terror attacks worldwide necessitate civilian-military collaboration. Such collaboration, however, needs to be synchronized and adjusted to avoid preventable medical and non-medical consequences. Simulation exercises might be one important source to improve such collaboration.

  14. From PCP to MXE: a comprehensive review of the non-medical use of dissociative drugs.

    Science.gov (United States)

    Morris, Hamilton; Wallach, Jason

    2014-01-01

    PCP or phencyclidine was discovered in 1956 and soon became a popular street drug. Dissociatives including PCP, ketamine, and dextromethorphan have been used non-medically for their mind-altering effects for over 60 years. Many of these compounds have also been used clinically and in legitimate research. At least 14 derivatives of PCP were sold for non-medical and illict use from the late 1960s until the 1990s. With the advent of the Internet, the drug market underwent a dramatic evolution. While initially gray-market chemical vendors offering dextromethorphan and ketamine thrived, most recently the market has shifted to legal high and online-based research chemical vendors. Starting with the first dissociative research chemical, 4-MeO-PCP in 2008, the dissociative research chemical market has rapidly evolved and currently comprises at least 12 dissociatives, almost half of which were unknown in the scientific literature prior to their introduction. Several of these, including methoxetamine, have reached widespread use internationally. A historical account of non-medical use of over 30 dissociative compounds was compiled from a diverse collection of sources. The first complete portrait of this underground market is presented along with the relevant legal, technological, and scientific developments which have driven its evolution. Copyright © 2014 John Wiley & Sons, Ltd.

  15. Reproduction opportunists in the new global sex trade: PGD and non-medical sex selection.

    Science.gov (United States)

    Whittaker, Andrea M

    2011-11-01

    Regulatory differences between countries are an important driver of the cross-border trade in assisted reproduction as people move to seek services unavailable in their home countries. The development of a lucrative global trade in non-medical sex selection needs to be considered in ethical debates over its availability. I suggest that depictions of non-medical sex selection as a means of 'family balancing' or supportive of reproductive autonomy serve to distance the technologies rhetorically from the gender stereotyping inherent in their use and the commodification upon which they depend. They construct new social categories such as the 'unbalanced' family, the pathologization of 'gender disappointment' and a limited and highly individualized definition of reproductive freedom that permits medical interventions on healthy bodies. Orientalism pervades ethical debate depicting non-medical sex selection in the West as more acceptable to practices in 'Asia'. A case study of the interconnections between Australia and Thailand highlights the global economy sustaining the practice. Copyright © 2011 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

  16. Non-medical use of prescription stimulants for academic purposes among college students: a test of social learning theory.

    Science.gov (United States)

    Ford, Jason A; Ong, Julianne

    2014-11-01

    The current research examines whether measures associated with Akers' social learning theory are related to non-medical use of prescription stimulants for academic reasons among college students. We examine data from a sample of 549 undergraduate students at one public university in the Southeastern United States. We estimate several logistic regression models to test our hypotheses. The findings indicated that roughly 17% of students reported non-medical use of prescription stimulants for academic reasons during the past year. In separate models, all four of the social learning measures were significantly correlated to non-medical use. In the complete model, the risk of non-medical prescription stimulant use for academic reasons was increased for respondents who reported more of their friends used and also for respondents who believed that prescription stimulants were an effective study aid. The current research fills an important gap in the literature regarding theoretical explanations for non-medical prescription stimulant use. Given the high prevalence of non-medical prescription stimulant use and the known risks associated with non-medical use this research can help inform intervention strategies for college populations. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  17. Oops Helping children learn accidentally

    CERN Document Server

    Hywel, Robert

    2012-01-01

    This book is about engaging learners in great learning. It's about the dance that happens behind positive engagement - the cool moves and steps a teacher needs to choreograph in order to create a context where great learning can happen - and about the importance of relationships in engagement and how rapport can be learned. The book also shines a spotlight on the role of the teacher and how he or she can do the right things to get the absolute best from students.Some of the best learning takes place when, rather than imposing on young people a pre-determined curriculum, you find the stimulus t

  18. KNOWLEDGE AWARENESS AND BEHAVIOUR OF NON-MEDICAL STUDENTS ABOUT CARDIOVASCULAR DISEASES.

    Science.gov (United States)

    Mustaqeem, Marium; Sadullah, Samiyah; Farooq, Muhammad Zain; Waqar, Wajiha; Fraz, Tayyab Raza

    2015-01-01

    Cardiovascular diseases is the leading cause of death worldwide, yet very little data is available assessing the awareness of the younger population of Pakistan. The purpose of this study was to evaluate the awareness, knowledge and the preventive measures taken to avoid the health issues related to cardiovascular diseases. It was a community based cross sectional descriptive study to assess the awareness and behavior in young non medical students. A questionnaire was developed and survey was conducted on 300 non medical students enrolled in different universities of Pakistan. Data analysis was performed using SPSS-16. The sample consisted of 300 students aged between 16 and 32 years. 6.7% of the participants had history of blood pressure, 0.7% had diabetes, and 68.3% had a family history of cardiovascular diseases. 17.4% students were smokers. In the knowledge section, only 22% respondent scored above 20 out of 28 showing lack of knowledge. 42.7% participants were concerned about developing coronary artery diseases. 43.3% and 6.7% knew their blood pressure and cholesterol level respectively.33.3% and 41.7% regulate their dietary fat and salt intake respectively. Our study elucidates that cardiovascular diseases are not perceived as major risk by Non Medical Students. Lack of knowledge, physical inactivity, and high positive family history render the target population prone to cardiovascular diseases. The findings of study indicates the need for heart disease awareness campaigns for young population, to escalate the preventive actions and adoption of healthy lifestyles so as to lower the incidence of cardiovascular diseases in Pakistan.

  19. An instrument for broadened risk assessment in antenatal health care including non-medical issues

    Directory of Open Access Journals (Sweden)

    Amber Amanda Vos

    2015-03-01

    Full Text Available Introduction: Growing evidence on the risk contributing role of non-medical factors on pregnancy outcomes urged for a new approach in early antenatal risk selection. The evidence invites to more integration, in particular between the clinical working area and the public health domain. We developed a non-invasive, standardized instrument for comprehensive antenatal risk assessment. The current study presents the application-oriented development of a risk screening instrument for early antenatal detection of risk factors and tailored prevention in an integrated care setting.Methods: A review of published instruments complemented with evidence from cohort studies. Selection and standardization of risk factors associated with small for gestational age, preterm birth, congenital anomalies and perinatal mortality. Risk factors were weighted to obtain a cumulative risk score. Responses were then connected to corresponding care pathways. A cumulative risk threshold was defined, which can be adapted to the population and the availability of preventive facilities. A score above the threshold implies multidisciplinary consultation between caregivers.Results: The resulting digital score card consisted of 70 items, subdivided into four non-medical and two medical domains. Weighing of risk factors was based on existing evidence. Pilot-evidence from a cohort of 218 pregnancies in a multi-practice urban setting showed a cut-off of 16 points would imply 20% of all pregnant women to be assessed in a multidisciplinary setting. A total of 28 care pathways were defined.Conclusion: The resulting score card is a universal risk screening instrument which incorporates recent evidence on non-medical risk factors for adverse pregnancy outcomes and enables systematic risk management in an integrated antenatal health care setting.

  20. An instrument for broadened risk assessment in antenatal health care including non-medical issues

    Directory of Open Access Journals (Sweden)

    Amber Amanda Vos

    2015-03-01

    Full Text Available Introduction: Growing evidence on the risk contributing role of non-medical factors on pregnancy outcomes urged for a new approach in early antenatal risk selection. The evidence invites to more integration, in particular between the clinical working area and the public health domain. We developed a non-invasive, standardized instrument for comprehensive antenatal risk assessment. The current study presents the application-oriented development of a risk screening instrument for early antenatal detection of risk factors and tailored prevention in an integrated care setting. Methods: A review of published instruments complemented with evidence from cohort studies. Selection and standardization of risk factors associated with small for gestational age, preterm birth, congenital anomalies and perinatal mortality. Risk factors were weighted to obtain a cumulative risk score. Responses were then connected to corresponding care pathways. A cumulative risk threshold was defined, which can be adapted to the population and the availability of preventive facilities. A score above the threshold implies multidisciplinary consultation between caregivers. Results: The resulting digital score card consisted of 70 items, subdivided into four non-medical and two medical domains. Weighing of risk factors was based on existing evidence. Pilot-evidence from a cohort of 218 pregnancies in a multi-practice urban setting showed a cut-off of 16 points would imply 20% of all pregnant women to be assessed in a multidisciplinary setting. A total of 28 care pathways were defined. Conclusion: The resulting score card is a universal risk screening instrument which incorporates recent evidence on non-medical risk factors for adverse pregnancy outcomes and enables systematic risk management in an integrated antenatal health care setting.

  1. NON-MEDICAL DRUG USE AMONG INTERNS AND HOUSE-OFFICERS

    Science.gov (United States)

    Choudhary, R. K.; Singh, Rajpal; Avasthi, Ajit; Gupta, Rajeev

    1980-01-01

    SUMMARY Self-administered questionnaire was given to a sample of 105 interns and house officers working in Govt. Medical College, Jammu. Questionnaire was designed to obtain information about socio-demographic characteristics, the frequency of non-medical drug use during the last one year and to enquire about “reasons” for drug intake. It was found that drugs commonly used were alcohol, tobacco, tranquillizers, amphetamines, cannabis. Most of the subjects used the same for ‘company’, festivity or curiosity. PMID:22058486

  2. The Berlin Brain-Computer Interface: Non-Medical Uses of BCI Technology

    Directory of Open Access Journals (Sweden)

    Benjamin Blankertz

    2010-12-01

    Full Text Available Brain-Computer Interfacing (BCI is a steadily growing area ofresearch. While initially BCI research was focused on applicationsfor paralyzed patients, increasingly more alternative applications inhealthy human subjects are proposed and investigated. In particular,monitoring of mental states and decoding of covert user states haveseen a strong rise of interest. Here, we present some examples ofsuch novel applications which provide evidence for the promisingpotential of BCI technology for non-medical uses. Furthermore, wediscuss distinct methodological improvements required to bringnon-medical applications of BCI technology to a diversity of laypersontarget groups, e.g., ease of use, minimal training, general usability,short control latencies.

  3. [Recognition of flavor in non-medical literatures of pre-Qin dynasty].

    Science.gov (United States)

    Zhang, Ruixian; Zhang, Wei

    2010-02-01

    By systemically sorting of non-medical literatures of pre-Qin dynasty such as the Thirteen Confucian Classics, etc, this article made an analysis on the meaning and content of flavor in that period with the Genesis and Epistemology, and pointed out that there were two meanings of the flavor: the first is the flavor or taste obtained by tasting, and the other is the five-elements flavor, a abstract flavor. The former flavor should be originated early than the later one. Besides, the article made a brief view on the functions of flavors in the health keeping and medicine.

  4. Pharmacology podcasts: a qualitative study of non-medical prescribing students' use, perceptions and impact on learning

    National Research Council Canada - National Science Library

    Meade, Oonagh; Bowskill, Dianne; Lymn, Joanne S

    2011-01-01

    ... of the usefulness of podcasts as learning tools. This study aimed to explore the experiences of non-medical prescribing students who had access to podcasts of key pharmacology lectures as supplementary learning tools to their existing course materials...

  5. The non-medical workforce and its role in surgical training: Consensus recommendations by the Association of Surgeons in Training.

    Science.gov (United States)

    Gokani, Vimal J; Peckham-Cooper, Adam; Bunting, David; Beamish, Andrew J; Williams, Adam; Harries, Rhiannon L

    2016-11-01

    Changes in the delivery of the healthcare structure have led to the expansion of the non-medical workforce (NMW). The non-medical practitioner in surgery (a healthcare professional without a medical degree who undertakes specialist training) is a valuable addition to a surgical firm. However, there are a number of challenges regarding the successful widespread implementation of this role. This paper outlines a number of these concerns, and makes recommendations to aid the realisation of the non-medical practitioner as a normal part of the surgical team. In summary, the Association of Surgeons in Training welcomes the development of the non-medical workforce as part of the surgical team in order to promote enhanced patient care and improved surgical training opportunities. However, establishing a workforce of independent/semi-independent practitioners who compete for the same training opportunities as surgeons in training may threaten the UK surgical training system, and therefore the care of our future patients.

  6. OOPS : une approche orientée objet pour l’interrogation et l’analyse linguistique de l’interface prosodie/syntaxe/discours

    Directory of Open Access Journals (Sweden)

    Beliao Julie

    2014-07-01

    Full Text Available Dans cet article, nous nous intéressons à la problématique de l'étude de la langue parlée multi-annotée. Dans de tels corpus, un même échantillon de parole est associé à des informations inhérentes à différents niveaux linguistiques. Cela soulève des problématiques liées à la difficulté d’organisation, de stockage et d’accès à ces informations pour l'analyse conjointe de niveaux linguistiques : intonosyntaxe, discours-prosodie et syntaxe-pragmatique par exemple. La principale difficulté qui sous-tend l'exploitation d'un tel corpus multi-annoté de langue parlée est la mise en relation d’unités qui appartiennent à des niveaux linguistiques différents. Pour tous les niveaux linguistiques représentés, chaque annotation conduit en effet à une hiérarchie particulière. L’agrégation de toutes ces hiérarchies ou arborescences linguistiques est l’enjeu du formalisme proposé. Pour étudier l'interface entre différents niveaux linguistiques, nous proposons une approche orientée objet OOPS (Object-Oriented Processing of Speech permettant de représenter une large variété d’annotations au sein d’une architecture globale. Une telle structure ne peut en effet pas être réalisée entièrement à partir de la seule transcription annotée, qui est au mieux exploitable par un humain. Elle nécessite au contraire une mise en relation du signal et des autres support d’annotation avec cette transcription pour l'étude conjointe d’unités linguistiques appartenant à des niveaux différents. La particularité de l’aproche que nous proposons est qu'elle repose entièrement sur un formalisme modulaire, ou objet. Une unité linguistique sera vue comme un objet (au sens informatique du terme de la hiérarchie dépendant du niveau linguistique auquel elle appartient. Ces différentes hiérarchies sont reliées par les mots de la transcription, qui leurs sont communs. Ainsi, il devient possible de faire des requ

  7. Disagreements with implications: diverging discourses on the ethics of non-medical use of methylphenidate for performance enhancement

    Directory of Open Access Journals (Sweden)

    Racine Eric

    2009-07-01

    Full Text Available Abstract Background There is substantial evidence that methylphenidate (MPH; Ritalin, is being used by healthy university students for non-medical motives such as the improvement of concentration, alertness, and academic performance. The scope and potential consequences of the non-medical use of MPH upon healthcare and society bring about many points of view. Methods To gain insight into key ethical and social issues on the non-medical use of MPH, we examined discourses in the print media, bioethics literature, and public health literature. Results Our study identified three diverging paradigms with varying perspectives on the nature of performance enhancement. The beneficial effects of MPH on normal cognition were generally portrayed enthusiastically in the print media and bioethics discourses but supported by scant information on associated risks. Overall, we found a variety of perspectives regarding ethical, legal and social issues related to the non-medical use of MPH for performance enhancement and its impact upon social practices and institutions. The exception to this was public health discourse which took a strong stance against the non-medical use of MPH typically viewed as a form of prescription abuse or misuse. Wide-ranging recommendations for prevention of further non-medical use of MPH included legislation and increased public education. Conclusion Some positive portrayals of the non-medical use of MPH for performance enhancement in the print media and bioethics discourses could entice further uses. Medicine and society need to prepare for more prevalent non-medical uses of neuropharmaceuticals by fostering better informed public debates.

  8. [Quality analysis by external users of the non-medical health transport unit of Alicante].

    Science.gov (United States)

    Soriano Clemor, C; Cano, F Soriano; Gimeno, F Morant

    2011-01-01

    Non-medical health transport has great health, media and social repercussions and requires a very considerable amount of human and economic resources. To describe the quality, evaluated by external users of our Health Department, in order to know what are the most important elements for external users. Cross-sectional, descriptive observational study. Population to study: patients with a social security health card who come to the Hospital of Alicante and are non-medical health transport unit users. Waiting time to be delivered to hospital in 92.7% of the cases was less than an hour, and was between one and two hours for 7.2%. The most frequent destinations were rehabilitation service and outpatient clinics. When users were asked if the would recommend this service, 60.9% said "for sure" and 39.1% said "probably yes". This study allows us to know patient needs and expectations, as well as the factors they value the most and which of our work areas to improve. Copyright © 2009 SECA. Published by Elsevier Espana. All rights reserved.

  9. Non-Medical Prescription Stimulant Use in Graduate Students: Relationship With Academic Self-Efficacy and Psychological Variables.

    Science.gov (United States)

    Verdi, Genevieve; Weyandt, Lisa L; Zavras, Brynheld Martinez

    2016-09-01

    The objective of this study was to examine graduate students' non-medical use of prescription stimulant medication, and the relationship between non-medical use of prescription stimulants with academic self-efficacy, psychological factors (i.e., anxiety, depression, and stress), and internal restlessness. The sample consisted of 807 graduate students from universities located in five geographic regions of the United States. Past-year rates of self-reported non-medical use were determined to be 5.9%, with overall lifetime prevalence of 17.5%. Observed self-reported non-medical use of prescription stimulant medications was significantly correlated with self-reported levels of anxiety and stress, various aspects of internal restlessness, and perceived safety of the medications. Findings support graduate students' motivations of non-medical prescription stimulant use to be both academic and social in nature. Effective prevention and education efforts are needed to help address the non-medical use of prescription stimulants by graduate students on university campuses. © The Author(s) 2014.

  10. Non medical prescribing leads views on their role and the implementation of non medical prescribing from a multi-organisational perspective

    Directory of Open Access Journals (Sweden)

    Carey Nicola

    2011-06-01

    Full Text Available Abstract Background In the United Kingdom, non-medical prescribing (NMP has been identified as one way to improve healthcare quality and efficiency. Healthcare organisations are charged with overseeing the clinical governance of NMP and guidance recommends the identification of a lead director to be responsible for its implementation. While over twelve million items are prescribed each year by the 50,000 qualified NMPs its uptake is inconsistent. Several studies have explored the barriers to NMP at a practice level, however little is known about the role the NMP lead and the implementation of NMP from an organisational perspective. The aim of this research was to explore the role of the organisational NMP lead across a range of practice settings within one Strategic Health Authority (SHA and consider the development of NMP from a multi-organisational perspective. Methods Semi-structured telephone interviews with 28 NMP leads across one SHA were undertaken by a trained qualitative researcher. Interviews addressed the purpose of the role and difficulties encountered; audiotapes were transcribed, coded and themes were identified. Results The NMP lead role comprised of four main functions; communication, coordinating, clinical governance and support. Factors hampering progress in overseeing the safe development of NMP included lack of clarity about the NMP lead role and responsibilities, strategic support and a lack of protected time. The extent to which clinical governance systems were in place across organisations was inconsistent. Where a strategic approach to its development was adopted, fewer barriers were encountered and NMP was more likely to become embedded within organisations. Conclusions The significant contribution that NMP leads play in embedding NMP within organisations should be acknowledged by clearer national guidance for this role and its responsibilities. Greater standardisation and consistency is required of clinical governance

  11. Medical and non-medical complications among children and adolescents with excessive body weight.

    Science.gov (United States)

    Maggio, Albane B R; Martin, Xavier E; Saunders Gasser, Catherine; Gal-Duding, Claudine; Beghetti, Maurice; Farpour-Lambert, Nathalie J; Chamay-Weber, Catherine

    2014-09-14

    The burden of disease from childhood obesity is considerable worldwide, as it is associated with several co-morbidities, such as dyslipidemia, hypertension, type 2 diabetes (T2DM), orthopedic and psychosocial problems. We aimed at determining the prevalence of these complications in a population of children and adolescents with body weight excess. This is a cohort study including 774 new patients (1.7 - 17.9 yrs, mean 11.1 ± 3.0) attending a pediatric obesity care center. We assessed personal and family medical histories, physical examination, systemic blood pressure, biochemical screening tests. We found that the great majority of the children suffered from at least one medical complication. Orthopedic pathologies were the most frequent (54%), followed by metabolic (42%) and cardiovascular disturbances (31%). However, non-medical conditions related to well-being, such as bullying, psychological complaints, shortness of breath or abnormal sleeping patterns, were present in the vast majority of the children (79.4%). Family history of dyslipidemia tends to correlate with the child's lipids disturbance (p = .053), and ischemic events or T2DM were correlated with cardiovascular risk factors present in the child (p = .046; p = .038, respectively). The vast majority of obese children suffer from medical and non-medical co-morbidities which must be actively screened. A positive family history for cardiovascular diseases or T2DM should be warning signs to perform further complementary tests. Furthermore, well-being related-complaints should not be underestimated as they were extremely frequent.

  12. Non-medical opioid use in youth: Gender differences in risk factors and prevalence.

    Science.gov (United States)

    Osborne, Vicki; Serdarevic, Mirsada; Crooke, Hannah; Striley, Catherine; Cottler, Linda B

    2017-09-01

    Non-medical use (NMU) of prescription opioids in youth is of concern since they may continue this pattern into adulthood and become addicted or divert medications to others. Research into risk factors for NMU can help target interventions to prevent non-medical use of opioids in youth. The National Monitoring of Adolescent Prescription Stimulants Study (N-MAPSS) was conducted from 2008 to 2011. Participants 10-18years of age were recruited from entertainment venues in urban, rural and suburban areas of 10 US cities. Participants completed a survey including questions on their use of prescription opioids. NMU was defined as a non-labeled route of administration or using someone else's prescription. Information on age, gender, alcohol, marijuana and tobacco use was also collected. Summary descriptive, chi-square statistics and logistic regression were conducted using SAS 9.4. Of the 10,965 youth who provided information about past 30day prescription opioid use, prevalence of reported opioid use was 4.8% with 3.2% reported as NMU (n=345) and 1.6% as medical use (MU) only (n=180). More males than females (55.7% vs. 44.4%) reported opioid NMU (p<0.0001). Logistic regression revealed that among males (comparing NMU to MU only), current smokers were 4.4 times more likely to report opioid NMU than non-smokers (95% CI: 1.8, 10.7). Among females (comparing NMU to MU only), current smokers and alcohol users were more likely to report opioid NMU than those who had never smoked or used alcohol (OR=3.2, 95% CI: 1.4, 7.0 and OR=4.1, 95% CI: 1.7, 10.4, respectively). These results suggest that further research on gender differences in opioid NMU is needed; interventions for opioid NMU may need to be gender specific to obtain the best results. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Knowledge and risk perception of oral cavity and oropharyngeal cancer among non-medical university students.

    Science.gov (United States)

    Osazuwa-Peters, Nosayaba; Tutlam, Nhial T

    2016-01-28

    To assess non-medical university students' knowledge and perceived risk of developing oral cavity and oropharyngeal cancer. A cross-sectional survey was conducted among non-medical students of a private Midwestern university in the United States in May 2012. Questionnaire assessed demographic information and contained 21 previously validated questions regarding knowledge and perceived risk of developing oral cavity and oropharyngeal cancer. Knowledge scale was categorized into low and high. Risk level was estimated based on smoking, drinking, and sexual habits. Bivariate associations between continuous and categorical variables were assessed using Pearson correlation and Chi-square tests, respectively. The response rate was 87% (100 out of 115 students approached). Eighty-one percent (81%) had low oral cavity and oropharyngeal cancer knowledge; and only 2% perceived that their oral cavity and oropharyngeal cancer risk was high. Risk perception was negatively correlated with age at sexual debut, r (64) = -0.26, p = 0.037; one-way ANOVA showed a marginally significant association between risk perception and number of sexual partners, F(4, 60) = 2.48, p = 0.05. There was no significant association between knowledge and perception of risk; however, oral cavity and oropharyngeal cancer knowledge was significantly associated with frequency of prevention of STDs (p perception is low among this student population. Since oral cavity and oropharyngeal cancer incidence is increasingly shifting towards younger adults, interventions must be tailored to this group in order to improve prevention and control.

  14. Non-medical prescribing versus medical prescribing for acute and chronic disease management in primary and secondary care.

    Science.gov (United States)

    Weeks, Greg; George, Johnson; Maclure, Katie; Stewart, Derek

    2016-11-22

    A range of health workforce strategies are needed to address health service demands in low-, middle- and high-income countries. Non-medical prescribing involves nurses, pharmacists, allied health professionals, and physician assistants substituting for doctors in a prescribing role, and this is one approach to improve access to medicines. To assess clinical, patient-reported, and resource use outcomes of non-medical prescribing for managing acute and chronic health conditions in primary and secondary care settings compared with medical prescribing (usual care). We searched databases including CENTRAL, MEDLINE, Embase, and five other databases on 19 July 2016. We also searched the grey literature and handsearched bibliographies of relevant papers and publications. Randomised controlled trials (RCTs), cluster-RCTs, controlled before-and-after (CBA) studies (with at least two intervention and two control sites) and interrupted time series analysis (with at least three observations before and after the intervention) comparing: 1. non-medical prescribing versus medical prescribing in acute care; 2. non-medical prescribing versus medical prescribing in chronic care; 3. non-medical prescribing versus medical prescribing in secondary care; 4 non-medical prescribing versus medical prescribing in primary care; 5. comparisons between different non-medical prescriber groups; and 6. non-medical healthcare providers with formal prescribing training versus those without formal prescribing training. We used standard methodological procedures expected by Cochrane. Two review authors independently reviewed studies for inclusion, extracted data, and assessed study quality with discrepancies resolved by discussion. Two review authors independently assessed risk of bias for the included studies according to EPOC criteria. We undertook meta-analyses using the fixed-effect model where studies were examining the same treatment effect and to account for small sample sizes. We compared

  15. Self-citation of Medical and Non-medical Universities in Northern Iran

    Science.gov (United States)

    Jahani, Mohammad Ali; Yaminfirooz, Mousa

    2016-01-01

    Background: Self-citation is one of the main challenges in the evaluation of researchers’ scientific output. This study aimed at comparing the institutional self-citation among the universities located in Northern Iran. Methods: This study was conducted as a scientometric study. Research population included all scientific productions of 16 Northern Iran Universities with at least 100 indexed documents indexed in the Web of Science (WoS) by 2 June 2015. The citation analysis section of WoS was used for data collection. SPSS was applied for data analysis. Study hypotheses were tested with two independent sample t-test and paired sample t-test. Results: Producing 16,399 papers, northern Iran universities had 5.33% of contribution in Iran’s scientific production. They received 84,058 citations with 17% and 12% of self-citations belonged to the non-medical and medical universities, respectively. Testing hypotheses revealed that increase in received citations significantly increases the rate of self-citation and increase in scientific production does not necessarily increase the rate of self-citation. Conclusion: The rate of self-citation in the studied universities was not relatively high. However, investigating into the factors affecting the rate of and motives for self-citation needs further research. PMID:28077903

  16. Religiosity in the non-medical use of prescription medication in college students.

    Science.gov (United States)

    Snipes, Daniel J; Jeffers, Amy J; Benotsch, Eric G; McCauley, Jessica; Bannerman, Dana; Granger, Catherine; Martin, Aaron M

    2015-01-01

    The non-medical use of prescription drugs (NMUPD) is a hazardous health behavior popular among young adults and college students. Past research has documented prevalence rates and risk factors associated with NMUPD, while little research has addressed protective factors. The present study examined the associations of religiosity and NMUPD in a sample of college students. Young adult (ages 18-25) college students (n = 767) completed an anonymous online survey assessing demographic variables, NMUPD, personality factors, perceptions of risk, mental health, and religiosity. Results showed that greater religiosity scores were consistently associated with lower odds of engaging in NMUPD in the past 3 months. These associations were partially mediated by the personality characteristics of conscientiousness and openness to experience as well as perceived risk of NMUPD. The effect of religiosity on NMUPD was moderated by Greek (i.e., fraternity or sorority) membership, such that those in a Greek organization showed no relation between religiosity and NMUPD, while religiosity served as a protective factor for NMUPD among those who did not have Greek membership. These results extend past research demonstrating that religiosity is protective against substance abuse/misuse. Greek status appears to negate the protective influence of religiosity on NMUPD.

  17. Potential applications of medical and non-medical robots for neurosurgical applications.

    Science.gov (United States)

    Alric, Matthieu; Chapelle, Frédéric; Lemaire, Jean-Jacques; Gogu, Grigore

    2009-01-01

    The objective of the paper is to review the state-of-the-art in medical robotic systems used for different surgical applications, and to position and evaluate their concepts according to the design requirements of an innovative, robotized neurosurgical system, capable of performing tumor ablation or electrode positioning. A few other non-medical systems, which have interesting concepts, will also be discussed. The overall aim is to determine the robotic concept (structure, actuation, etc.) most applicable to specific tasks in neurosurgery. The first section of the article describes the requirements of the task and each important aspect is expressed by an evaluation criterion. Then, 59 systems are described, according to the fields of medical applications and the robotic concepts. An evaluation of the different systems is conducted, based on the five most significant criteria. However, the main characteristic assessed is the deployment capability of the system i.e. extension and retraction. The final section presents an overview of concepts transferable to neurosurgical applications. Continuum concepts, such as "elephant trunks", seem to be the most adapted solutions, utilizing pneumatic and/or spring and/or cable actuations. Pneumatics offer deployment forces and cables can control and guide the deployment. The design of a new neurosurgical device should take into account these observations as a base.

  18. Determinants of non-medically indicated cesarean deliveries in Burkina Faso.

    Science.gov (United States)

    Kaboré, Charles; Ridde, Valéry; Kouanda, Seni; Agier, Isabelle; Queuille, Ludovic; Dumont, Alexandre

    2016-11-01

    To identify the factors associated with non-medically indicated cesarean deliveries (NMIC) in Burkina Faso in centers where user fees for cesarean delivery were partially removed. We carried out a criteria-based audit in 22 referral hospitals, using data from a 6-month prospective observational study, to assess the proportion of NMIC. Multivariate logistic regression analyses were used to identify factors associated with NMIC. The decision of cesarean delivery was not medically indicated in 24% of cases. The factors independently associated with NMIC were urban residence (adjusted OR 1.55; 95% CI, 1.12-2.12; P=0.006), spouse's occupation other than breeder or farmer (aOR varying from 1.77 [95% CI, 1.19-2.62] to 2.15 [95% CI, 1.38-3.32] according to the profession), and cesarean decided by a general practitioner (aOR 1.61; 95% CI, 1.13-2.30; P=0.009). The high percentage of unnecessary cesarean deliveries is in contrast to the unmet needs of women who still deliver outside health facilities. NMIC is associated with both socioeconomic determinants and medical factors. Hence, interventions are needed to improve the skills of healthcare professionals and awareness of women concerning the risks associated with unnecessary cesarean delivery. Copyright © 2016 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

  19. Meta-analysis of non-medical treatments for chronic pain.

    Science.gov (United States)

    Malone, M D; Strube, M J; Scogin, F R

    1988-09-01

    A meta-analysis was conducted on 109 published studies which assessed the outcome of various non-medical treatments for chronic pain. Of these studies, 48 provided sufficient information to calculate effect sizes. The remainder were examined according to proportion of patients rated as improved. Studies were compared as a function of type of treatment, type of pain, and type of outcome variable. In general, effect sizes were positive and of modest magnitude indicating the short-term efficacy of most treatments for most types of pain. This finding suggests that the effectiveness of treatments may be attributable not to the differences between treatments, but to the features they have in common. Mood and number of subjective symptoms consistently showed greater responses to treatment than did pain intensity, pain duration, or frequency of pain, indicating the importance of using a multidimensional framework for pain assessment. This finding also suggests that the benefit of psychological approaches to pain management may lie in reducing the fear and depression associated with pain, rather than relieving the pain itself. The present study also highlights the advantages of meta-analytic reviews.

  20. The use of non-medical/alternative treatment in multiple sclerosis. A 5 year follow-up study

    DEFF Research Database (Denmark)

    Stenager, Egon; Stenager, E N; Knudsen, Lone;

    1995-01-01

    Forty-nine patients (22 males, 27 females) were examined and interviewed with 5 years interval in order to determine the extent of the use of non-medical (alternative) treatment and whether the use influenced the natural course of multiple sclerosis (MS). Using clinical course, Kurtzke Disability...

  1. Perceptions of personal health risks by medical and non-medical workers in a university medical center : a survey study

    NARCIS (Netherlands)

    Listyowardojo, Tita Alissa; Nap, Raoul E.; Johnson, Addie

    2010-01-01

    Background: Health care workers (HCWs) are faced with many work-related choices which may depend on how they perceive risk, such as whether or not to comply with safety regulations. Little research has investigated risk perception in medical workers in comparison with non-medical workers and the ext

  2. Perceptions of personal health risks by medical and non-medical workers in a university medical center : a survey study

    NARCIS (Netherlands)

    Listyowardojo, Tita Alissa; Nap, Raoul E.; Johnson, Addie

    2010-01-01

    Background: Health care workers (HCWs) are faced with many work-related choices which may depend on how they perceive risk, such as whether or not to comply with safety regulations. Little research has investigated risk perception in medical workers in comparison with non-medical workers and the ext

  3. Medical and non-medical expenditure for breast cancer diagnosis and treatment in China: a multicenter cross-sectional study.

    Science.gov (United States)

    Liao, Xian-Zhen; Shi, Ju-Fang; Liu, Jing-Shi; Huang, Hui-Yao; Guo, Lan-Wei; Zhu, Xin-Yu; Xiao, Hai-Fan; Wang, Le; Bai, Ya-Na; Liu, Guo-Xiang; Mao, A-Yan; Ren, Jian-Song; Sun, Xiao-Jie; Mai, Ling; Liu, Yu-Qin; Song, Bing-Bing; Gong, Ji-Yong; Zhou, Jin-Yi; Du, Ling-Bing; Zhou, Qi; Cao, Rong; Zhu, Lin; Ren, Ying; Lou, Pei-An; Lan, Li; Sun, Xiao-Hua; Qi, Xiao; Wang, Yuan-Zheng; Zhang, Kai; He, Jie; Dai, Min

    2017-07-03

    We aimed to assess economic burden of breast cancer (BC) diagnosis and treatment in China through a multicenter cross-sectional study, and to obtain theoretical evidence for policy-making. This survey was conducted in 37 hospital centers across 13 provinces in China from September 2012 to December 2014. We collected information on the subject characteristics. We then assessed the medical and non-medical expenditure for BC diagnosis and treatment, factors influencing the average case expense, variations between medical and non-medical expenditure at different clinical stages, economic impact of overall expenditure in newly diagnosed course after reimbursement to the patient's family, composition of non-medical expenditure and time loss for the patient and family. Among 2746 women with BC (72.6% were admitted to specialized hospitals), the overall average expenditure was US $8450 (medical expenditure: $7527; non-medical expenditure: $922). Significant differences were found among the overall expenditure in the four clinical stages (P < 0.0001); the expenditure was higher in stages III and IV than that in stages I and II, whereas the stage IV was the highest (P < 0.0001). Moreover, a higher self-reported predicted reimbursement ratio was associated with a less economic impact on the patient's family, and the average time lost was estimated as $1529. Early detection and treatment of breast cancer might be effective for decreasing the economic burden, because costs escalate as the degree of malignancy increases. © 2017 John Wiley & Sons Australia, Ltd.

  4. Non-medical prescribing by physiotherapists: issues reported in the current evidence.

    Science.gov (United States)

    Morris, Joanne H; Grimmer, Karen

    2014-02-01

    Physiotherapists should be proactive in preparing themselves to participate in innovative models of health care, which are emerging from the healthcare workforce reforms in Australia. One challenging outcome of workforce change is physiotherapy (non-medical) prescribing (NMP), which is part of the extension of scope of physiotherapy practice. This paper summarises the current evidence base for Australian physiotherapists seeking to obtain prescribing rights. A targeted literature review was undertaken through EBSCO Host, Cochrane, Medline, SportsDiscus, Cinahl, Healthsource and Google.com using broad search terms to identify peer-reviewed and grey literature pertaining to NMP by physiotherapists, nationally and internationally. No critical appraisal was undertaken however literature was structured into the NHMRC hierarchy of evidence. Themes raised in the included literature were reported descriptively. There were six relevant peer-reviewed articles, of hierarchy levels III_3 and IV. There was however, comprehensive and recent grey literature to inform Australian physiotherapy NMP initiatives. Themes included the need for standard National action in relation to legislative and regulatory/registration issues, appropriate education, credentialing and supervisory requirements for physiotherapy prescribing. Many lessons can be learnt from the literature, including the importance of planned, uniform National action (rather than piecemeal state-by-state initiatives). Essential elements include appropriate training and skills-based recognition within the discipline and the broader health team, and the need to overtly demonstrate effectiveness and safety. Regularly-evaluated service-delivery models which support NMP by physiotherapists are further required, to demonstrate efficiency, timeliness, patient centredness and equity. Crown Copyright © 2013. Published by Elsevier Ltd. All rights reserved.

  5. [Turnover of Non-medical Staff in Outpatient Oncology Practices: Is Building Social Capital a Solution?].

    Science.gov (United States)

    Gloede, T D; Ernstmann, N; Baumann, W; Groß, S E; Ansmann, L; Nitzsche, A; Neumann, M; Wirtz, M; Schmitz, S; Schulz-Nieswandt, F; Pfaff, H

    2015-11-01

    While a lot is known about potential and actual turnover of non-medical hospital staff, only few data exist for the outpatient setting. In addition, little is known about actual instruments which leaders can use to influence staff turnover in physician practices. In the literature, the social capital of an organisation, which means the amount of trust, common values and reciprocal behaviour in the organisation, has been discussed as a possible field of action. In the present study, staff turnover as perceived by outpatient haematologists and oncologists is presented and analysed as to whether social capital is associated with that staff turnover. In conclusion, measures to increase the social capital of a practice are presented. The present study is based on data gathered in a questionnaire-based survey with members of the Professional Organisation of -Office-Based Haematologists and Oncologists (N=551). The social capital of the practice was captured from the haematologists and oncologists using an existing and validated scale. To analyse the impact of the practice's social capital on staff turnover, as perceived by the physicians, bivariate correlations and linear regression analyses were calculated. In total, 152 haematologists and oncologists participated in the study which represents a response rate of 28%. In the regression analyses, social capital appears as a significant and strong predictor of staff turnover (beta=-0.34; pstaff turnover although the underlying study design does not allow for drawing causal conclusions regarding this relationship. To create social capital in their practice, outpatient physicians may apply measures that facilitate social interaction among staff, foster trust and facilitate cooperation. Such measures may already be applied when hiring and training new staff, but also continuously when leading employees and when organising work tasks, e.g., by establishing regular team meetings. © Georg Thieme Verlag KG Stuttgart · New York.

  6. The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain.

    Science.gov (United States)

    Nagai, Fumiko; Nonaka, Ryouichi; Satoh Hisashi Kamimura, Kanako

    2007-03-22

    We developed a reproducible, simple, and small-scale method for determining the re-uptake and release of monoamines (dopamine, serotonin (5-HT) and norepinephrine) using rat brain synaptosomes. These assays were then applied to study the effects of different kinds of non-medically used psychoactive drugs on monoamine re-uptake and release. The phenethylamine derivatives, 4-fluoroamphetamine, 2-methylamino-3,4-methylene-dioxy-propiophenone (methylone), 1-(1,3-benzodioxol-5-yl)-2-butanamine (BDB), and N-methyl-1-(1,3-benzodioxol-5-yl)-2-butanamine (MBDB), had strong inhibitory effects on the re-uptake of dopamine, 5-HT and norepinephrine. 4-Fluoroamphetamine, methylone and BDB also strongly increased the release of the three monoamines, but MBDB increased 5-HT and norepinephrine release, but had little effect on dopamine release. However, 2,5-dimethoxy-4-iodophenethylamine (2C-I), 2,5-dimethoxy-4-ethylphenethylamine (2C-E), 2,5-dimethoxy-4-chlorophenethylamine (2C-C), 2,4,5-trimethoxyamphetamine (TMA-2) and 2,4,6-trimethoxyamphetamine (TMA-6), which are methoxylated phenethylamine derivatives, slightly influenced the re-uptake and release of monoamines. Alpha-metyltryptamine (AMT), a tryptamine derivative, was one of the strongest re-uptake inhibitors and releasers of the three monoamines. The tryptamine derivative, 5-methoxy-alpha-methyltryptamine (5-MeO-AMT), also strongly inhibited re-uptake and increased the release of the three monoamines. N,N-dipropyltryptamine (DPT), 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT), 5-methoxy-N,N-methylisopropyltryptamine (5-MeO-MIPT), and 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) inhibited monoamine re-uptake, but had a few effects on monoamine release. 1-(3-Chlorophenyl)piperazine (3CPP) and 1-(methoxyphenyl)piperazine (4MPP), which are piperazine derivatives, inhibited monoamine re-uptake and accelerated their release. The results suggest that some designer drugs strongly act on the central nerve system to the same

  7. Quantitative assessment of the nociceptive withdrawal reflex in healthy, non-medicated experimental sheep.

    Science.gov (United States)

    Rohrbach, Helene; Zeiter, Stephan; Andersen, Ole K; Wieling, Ronald; Spadavecchia, Claudia

    2014-04-22

    This study aimed to characterize the nociceptive withdrawal reflex (NWR) and to define the nociceptive threshold in 25 healthy, non-medicated experimental sheep in standing posture. Electrical stimulation of the dorsal lateral digital nerves of the right thoracic and the pelvic limb was performed and surface-electromyography (EMG) from the deltoid (all animals) and the femoral biceps (18 animals) or the peroneus tertius muscles (7 animals) was recorded. The behavioural reaction following each stimulation was scored on a scale from 0 (no reaction) to 5 (strong whole body reaction). A train-of-five 1ms constant-current pulse was used and current intensity was stepwise increased until NWR threshold intensity was reached. The NWR threshold intensity (It) was defined as the minimal stimulus intensity able to evoke a reflex with a minimal Root-Mean-Square amplitude (RMSA) of 20μV, a minimal duration of 10ms and a minimal reaction score of 1 (slight muscle contraction of the stimulated limb) within the time window of 20 to 130ms post-stimulation. Based on this value, further stimulations were performed below (0.9It) and above threshold (1.5It and 2It). The stimulus-response curve was described. Data are reported as medians and interquartile ranges. At the deltoid muscle It was 4.4mA (2.9-5.7) with an RMSA of 62μV (30-102). At the biceps femoris muscle It was 7.0mA (4.0-10.0) with an RMSA of 43μV (34-50) and at the peroneus tertius muscle It was 3.4mA (3.1-4.4) with an RMSA of 38μV (32-46). Above threshold, RMSA was significantly increased at all muscles. Below threshold, RMSA was only significantly smaller than at It for the peroneus tertius muscle but not for the other muscles. Data achieved in this study serve as reference for experimental or clinical applications of the conscious sheep model. Copyright © 2014 Elsevier Inc. All rights reserved.

  8. Non- medical prescribing in Australasia and the UK: the case of podiatry

    Directory of Open Access Journals (Sweden)

    Nancarrow Susan A

    2010-01-01

    Full Text Available Abstract Background The last decade has witnessed a rapid transformation in the role boundaries of the allied health professions, enabled through the creation of new roles and the expansion of existing, traditional roles. A strategy of health care 'modernisation' has encompassed calls for the redrawing of professional boundaries and identities, linked with demands for greater workforce flexibility. Several tasks and roles previously within the exclusive domain of medicine have been delegated to, or assumed by, allied health professionals, as the workforce is reshaped to meet the challenges posed by changing demographic, social and political contexts. The prescribing of medicines by non-medically qualified healthcare professionals, and in particular the podiatry profession, reflects these changes. Methods Using a range of key primary documentary sources derived from published material in the public domain and unpublished material in private possession, this paper traces the development of contemporary UK and Australasian podiatric prescribing, access, supply and administration of medicines. Documentary sources include material from legislative, health policy, regulatory and professional bodies (including both State and Federal sources in Australia. Results Tracing a chronological, comparative, socio-historical account of the emergence and development of 'prescribing' in podiatry in both Australasia and the UK enables an analysis of the impact of health policy reforms on the use of, and access to, medicines by podiatrists. The advent of neo-liberal healthcare policies, coupled with demands for workforce flexibility and role transfer within a climate of demographic, economic and social change has enabled allied health professionals to undertake an expanding number of tasks involving the sale, supply, administration and prescription of medicines. Conclusion As a challenge to medical dominance, these changes, although driven by wider healthcare

  9. Sinus node dysfunction in non-medicational treatment of atrial fibrillation

    Directory of Open Access Journals (Sweden)

    Bockeria L. А.

    2012-12-01

    Full Text Available Sinus node dysfunction or sick sinus syndrome (SSS includes clinical conditions such as symptomatic sinus bradycardia, sinus pauses or arrest, sinus node exit block, atrial tachycardias and chronotropic incompetence. Even though SSS incidence increases in an exponential-like manner with age, it can occur at all ages, including in the newborn. The mean age of patients with the syndrome is 68 years, with both genders being affected in approximately equal proportion. This condition occurs in 1 of every 600 cardiac patients over 65. Degenerative fibrosis of the tissues of the node has been suggested to be a common cause of SSS. Although it is still disputed. SSS is frequently associated with atrial fibrillation and flutter, tachy-bradycardia syndrome. Tachy-bradycardia syndrome is defined as sinus bradycardia coupled with atrial flutter/fibrillation or reciprocal atrial tachycardia. This syndrome is common in young patients following a surgical treatment of a congenital heart disease. Patients with chronic or persistent atrial flutter/fibrillation show high rates of cardiovascular disorders and mortality while sinus bradycardia is thought as an independent risk factor of atrial flutter/fibrillation. There are certain restrictions to medical treatment: long-term administration of the same medication (sotalol, amiodarone for atrial flutter/fibrillation can cause symptomatic bradycardia while administration of other medication (a class 1 drug increases the likelihood of ventricular arrythmias or evident bradycardia that enhances the risk of sudden cardiac death. Following atrial fibrillation ablation patients saw a significant improvement in the sinus node function, or saw a better sinus node function disrupted due to remodelling that takes place during atrial fibrillation. The surgical methods applications proved most efficient in non-medicational treatment of atrial fibrillation. In the late 1980s American surgeon J. L. Cox developed a so-called Maze

  10. Other-regarding behavior and motivation in health care provision: an experiment with medical and non-medical students.

    Science.gov (United States)

    Hennig-Schmidt, Heike; Wiesen, Daniel

    2014-05-01

    Other-regarding motivation is a fundamental determinant of public service provision. In health care, one example is physicians who act benevolently towards their patients when providing medical services. Such patient-regarding motivation seems closely associated with a personal sacrifice that health service providers are willing to make. Surprisingly, evidence on physicians' motivation is rare. This paper contributes to the literature by investigating prospective physicians', in particular, medical students', motivations and behavior. We measure the willingness to sacrifice own profit in order to increase the patients' health benefit. We conduct the same analysis for non-medical students. In a controlled incentivized laboratory experiment, participants decide, in the role of physicians, on the provision of medical services under fee-for-service or capitation schemes. Overall, 42 medical students and 44 non-medical students participated in five experimental sessions conducted between 2006 and 2008. We find substantial differences under both payment systems: compared to medical students, students of non-medical majors are less patient-regarding, less willing to sacrifice their own profit, and they state less motivation to improve patients' health. This results in significantly lower patient health benefits. Some implications for health care policies in light of physician shortage and for physician payment systems are discussed.

  11. Physical activity students of the medical and non-medical degree courses

    Directory of Open Access Journals (Sweden)

    Lucyna Sochocka

    2013-06-01

    Full Text Available Introduction: Recognition of the multiple positive effects of the physical activity confirms its influence on human’s health. Undertaking of the health oriented conducts plays an important role in the promotion of the health and in the creating of the healthier future. Academic youth should be aware of the influence of certain activities on health. The aim of the research was to analyse the physical activity performed by the full-time students of the medical and nonmedical degree courses. Material and methods: The research was conducted at the turn of 2012 and 2013. The research group, containing 553 person (n4553, consisted of the students from six Polish, both medical and non-medical, university colleges. The research utilizes the method of the diagnostic survey. Technique of the research based on the poll whose questionnaire had been created by the authors for the purpose of the research. Accuracy of the research tool was established within the method of objective judges, splithalf method was used to determine reliability (according to Spearman-Brown result 0.86. In order to define the existence of the differences or correlations between analysed immeasurable parameters chi-squared and Fisher’s exact tests were used. Results: The substantial majority of the respondents – 79,5% (n4439 described themselves as physically active. The forms of activity that are performed most often among the students are: cycling – 40,5% (n4220, team sport – 27,1% (n4147, dog walking – 27,1% (n4147, group activities (aerobics, zumba, salsa – 21,2% (n4115 and swimming – 20,8% (n4113. The sex and the faculty of the studies are both important variables that have got statistically significant impact on the choice of the form of activity. Majority of the respondents – 78,3% (n4432 chooses the type of the physical activity basing on their likings and the amount of the spare time – 42,9% (n4237. Exercising of the physical activity is regarded as a

  12. Determinants of intention to leave among non-medical employees after a nuclear disaster: a cross-sectional study

    Science.gov (United States)

    Takeda, Saeka; Orita, Makiko; Fukushima, Yoshiko; Kudo, Takashi; Takamura, Noboru

    2016-01-01

    Objective To conduct a survey among non-medical employees working at the time of the Fukushima Daiichi Nuclear Power Station accident, in order to determine the factors associated with their intentions to leave their jobs during the nuclear disaster. Participants We asked 287 employees (166 men and 121 women) in the study. Methods We asked about their intentions to leave their jobs after the nuclear disaster. We also asked about relevant factors, including the participants’ demographic factors, living situations and working environments. Results We found that in employees younger than 40 (OR=4.73, 95% CI 1.74 to 12.85, p=0.002), being married (OR=3.18, 95% CI 1.03 to 9.79, p=0.044), measurements of the ambient dose rates in their homes after the accident (OR=5.32, 95% CI 1.65 to 17.14, p=0.005), anxiety about their relationships with their colleagues after the accident (OR=3.91, 95% CI 1.51 to 10.16, p=0.005) and the influence of radiation on the workplace (OR=0.33, 95% CI 0.14 to 0.80, p=0.014) were independently associated with the non-medical employees’ intentions to leave their jobs after the nuclear disaster. Conclusions Our results suggest the need for continuous risk communication regarding such factors and the provision of information about the health effects of radiation exposure to non-medical employees after nuclear disasters. PMID:27436669

  13. Non-medical use of prescription drugs among illicit drug users: A case study on an online drug forum.

    Science.gov (United States)

    Rönkä, Sanna; Katainen, Anu

    2017-01-01

    The non-medical use of prescription drugs is a growing phenomenon associated with increasing health-related harms. However, little is known about the drivers of this process among illicit drug users. Our aim is to show how the qualities of pharmaceutical drugs, pharmaceutical related knowledge, online communities sharing this knowledge and medical professionals mediate and transform the consumption behaviour related to pharmaceutical drugs. The data consist of discussion threads from an online drug use forum. Using actor network theory (ANT), we analysed translations that mediate the online user community's relationship with pharmaceutical drugs. Differences in experienced drug effects are explained both as a process of 'learning' and as differences in brain chemistry at the receptor level. Both science- and experience-based information are shared on best practices to optimise use, avoid adverse health effects and maximise the experience of intoxication. The expanded context of doctors' practices places stress on the medical framework for drug use. Our analysis shows how the non-medical use of psychoactive pharmaceuticals relates to joint, medicalised ideas of bodies as sites of medical experimentation, as well as to the collective process of constructing 'pharmaceutical competences' in user networks. Understandings of intoxication have increasingly been permeated with the pharmacological and scientific logic of knowledge. The forum works as a platform for harm reduction inspired exchange of knowledge. However, the user community's knowledge sharing practices can generate a shared perception of a sufficient or even superior drug use experience and knowledge. This may lead to overdoses and other risky behaviour, and thereby contribute to increased harms related to non-medical use of prescription drugs. Copyright © 2016 Elsevier B.V. All rights reserved.

  14. Enforcement actions: Significant actions resolved material licensees (non-medical). Quarterly progress report, October 1994--December 1994

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-02-01

    This compilation summarizes significant enforcement actions that have been resolved during one quarterly period (October - December 1994) and includes copies of letters, Notices, and Orders sent by the Nuclear Regulatory Commission to material licensees (non-medical) with respect to these enforcement actions. It is anticipated that the information in this publication will be widely disseminated to managers and employees engaged in activities licensed by the NRC, so that actions can be taken to improve safety by avoiding future violations similar to those described in this publication.

  15. Children's anxious reactions to an invasive medical procedure: The role of medical and non-medical fears.

    Science.gov (United States)

    Fox, Jeremy K; Halpern, Leslie F; Dangman, Barbara C; Giramonti, Karla M; Kogan, Barry A

    2016-08-01

    This study investigated the relationship of medical and non-medical fears to children's anxiety, pain, and distress during an invasive medical procedure, the voiding cystourethrogram. Parents of 34 children completed the Fear Survey Schedule-II prior to their child's procedure. Child distress behaviors during the procedure were audiotaped and coded using the Child-Adult Medical Procedure Interaction Scale-Revised. Ratings of child procedural anxiety and pain were obtained from children, parents, and examining technologists within minutes following the procedure. Associations were observed between medical fears, procedural anxiety (parent and staff reports), and coded distress behaviors. Findings may inform preparation efforts to reduce anxiety around invasive medical procedures.

  16. Disparities in HIV knowledge and attitudes toward biomedical interventions among the non-medical HIV workforce in the United States.

    Science.gov (United States)

    Copeland, Raniyah M; Wilson, Phill; Betancourt, Gabriela; Garcia, David; Penner, Murray; Abravanel, Rebecca; Wong, Eric Y; Parisi, Lori D

    2017-04-27

    Non-medical, community-based workers play a critical role in supporting people living with (or at risk of acquiring) HIV along the care continuum. The biomedical nature of promising advances in HIV prevention, such as pre-exposure prophylaxis and treatment-as-prevention, requires frontline workers to be knowledgeable about HIV science and treatment. This study was developed to: measure knowledge of HIV science and treatment within the HIV non-medical workforce, evaluate workers' familiarity with and attitudes toward recent biomedical interventions, and identify factors that may affect HIV knowledge and attitudes. A 62-question, web-based survey was completed in English or Spanish between 2012 and 2014 by 3663 US-based employees, contractors, and volunteers working in AIDS service organizations, state/local health departments, and other community-based organizations in a non-medical capacity. Survey items captured the following: respondent demographics, HIV science and treatment knowledge, and familiarity with and attitudes toward biomedical interventions. An average of 61% of HIV knowledge questions were answered correctly. Higher knowledge scores were associated with higher education levels, work at organizations that serve people living with HIV/AIDS or who are at a high risk of acquiring HIV, and longer tenure in the field. Lower knowledge scores were associated with non-Hispanic Black or Black race/ethnicity and taking the survey in Spanish. Similarly, subgroup analyses showed that respondents who were non-Hispanic Black or Hispanic (versus non-Hispanic white), as well as those located in the South (versus other regions) scored significantly lower. These subpopulations were also less familiar with and had less positive attitudes toward newer biomedical prevention interventions. Respondents who took the survey in Spanish (versus English) had lower knowledge scores and higher familiarity with, but generally less positive attitudes toward, biomedical interventions

  17. Development of a Modified Korean East Asian Student Stress Inventory by Comparing Stress Levels in Medical Students with Those in Non-Medical Students

    OpenAIRE

    Shin, Hee Kon; Kang, Seok Hoon; Lim, Sun-Hye; Yang, Jeong Hee; Chae, Sunguk

    2016-01-01

    Background Medical students are usually under more stress than that experienced by non-medical students. Stress testing tools for Korean medical students have not been sufficiently studied. Thus, we adapted and modified the East Asian Student Stress Inventory (EASSI), a stress testing tool for Korean students studying abroad, and verified its usefulness as a stress test in Korean university students. We also compared and analyzed stress levels between medical and non-medical students. Methods...

  18. Evaluation of Female Youth Educational Needs about Reproductive Health in Non-Medical Students in the City of Qom.

    Directory of Open Access Journals (Sweden)

    Fatemeh Bazarganipour

    2013-06-01

    Full Text Available To evaluate reproductive health education which is essential to the prevention of sexual risk behavior and its associated adverse outcomes of unwanted pregnancy, AIDS and other sexually transmitted disease in adolescents. Little is known about youth educational needs about reproductive health in Iran. The aim of this study is evaluation of female youth educational needs about reproductive health in non-medical universities in the city of Qom, north central of Iran.The study was descriptive-analytical type conducted in nine non-medical universities (400 students. A questionnaire was constructed to meet the purpose of the study based on similar studies of knowledge and attitude in different countries, yet it was modified according to Iranian culture and social norms.The findings showed that a majority of participants have moderate knowledge about all components of reproductive health. Approximately, one - third of the participants reported difficulties to discuss about sexual health with mothers. The most of the participants believed insufficient female youth reproductive health services and low knowledge about reproductive health were the main barriers for female youth reproductive health aims.The participants in this study are representatives of an important subgroup in Iran in order to evaluate female youth reproductive health educational needs. The study identified many misconception and negative attitude that need to be addressed. A health education program through parents, peers, mass media campaign and more comprehensive family planning curriculum in universities are recommended to overcome misconception and spread awareness.

  19. Evaluation of Female Youth Educational Needs about Reproductive Health in Non-Medical Students in the City of Qom

    Science.gov (United States)

    Bazarganipour, Fatemeh; Foroozanfard, Fatemeh; Taghavi, Seyed Abdolvahab; Hekmatzadeh, Fatemeh; Sarviye, Malihe

    2013-01-01

    Objective To evaluate reproductive health education which is essential to the prevention of sexual risk behavior and its associated adverse outcomes of unwanted pregnancy, AIDS and other sexually transmitted disease in adolescents. Little is known about youth educational needs about reproductive health in Iran. The aim of this study is evaluation of female youth educational needs about reproductive health in non-medical universities in the city of Qom, north central of Iran. Materials and methods The study was descriptive-analytical type conducted in nine non-medical universities (400 students). A questionnaire was constructed to meet the purpose of the study based on similar studies of knowledge and attitude in different countries, yet it was modified according to Iranian culture and social norms. Results The findings showed that a majority of participants have moderate knowledge about all components of reproductive health. Approximately, one - third of the participants reported difficulties to discuss about sexual health with mothers. The most of the participants believed insufficient female youth reproductive health services and low knowledge about reproductive health were the main barriers for female youth reproductive health aims. Conclusion The participants in this study are representatives of an important subgroup in Iran in order to evaluate female youth reproductive health educational needs. The study identified many misconception and negative attitude that need to be addressed. A health education program through parents, peers, mass media campaign and more comprehensive family planning curriculum in universities are recommended to overcome misconception and spread awareness. PMID:24971106

  20. Performing 'pragmatic holism': Professionalisation and the holistic discourse of non-medically qualified acupuncturists and homeopaths in the United Kingdom.

    Science.gov (United States)

    Givati, Assaf

    2015-01-01

    Complementary and alternative medicine practitioners have often utilised 'holism' as a key identification mark of their practice, distancing themselves from 'the reductionist biomedicine'. However, the past couple of decades have witnessed increased engagement of several complementary and alternative medicines in professionalisation, which includes a degree of biomedical alignment while 'reducing' holistic claims in order to provide practice with a 'credible outlook' and move closer to the mainstream, a development which challenges the role of holism in complementary and alternative medicine practices. This article explores the strategies by which two groups of complementary and alternative medicine practitioners, namely, non-medically qualified acupuncturists and homeopaths in the United Kingdom, pragmatically accommodate holistic notions as a professional resource, a process of negotiation between maintaining their holistic premise, on the one hand, and the drive to professionalise and enhance their societal status, on the other. Based on in-depth interviews with non-medically qualified acupuncture and homeopathy practitioners and school principals, textual analysis of practitioners' web sites and observation of practice, the findings demonstrate the dynamic approach to 'holism' in complementary and alternative medicine practice. This discourse, through which practitioners use a range of strategies in order to 'narrow' or 'expand' their holistic expression, can be described as 'pragmatic holism', by which they try to make gains from the formalisation/standardisation processes, without losing the therapies' holistic outlook and appeal.

  1. Impact of alcohol and alcohol mixed with energy drinks on non-medical prescription stimulant use in a nationally representative sample of 12th-grade students.

    Science.gov (United States)

    Housman, Jeff M; Williams, Ronald D; Woolsey, Conrad L

    2016-08-01

    Approximately 30% of high school students use energy drinks. Alcohol use and alcohol mixed with energy drink use (AmED) is associated with risky behavior, including non-medical prescription stimulant use. We assessed alcohol-only, AmED and non-medical prescription stimulant use among 12th grade students in the U.S. using a nationally representative secondary data from the 2012 Monitoring the Future Study. Wilcoxon-Mann-Whitney tests and logistic regression analyses were used to determine differences in non-medical prescription stimulant use by students who used alcohol-only versus AmED and to identify covariates of non-medical prescription stimulant use. Pearson-product moment coefficients were used to determine strength of variable relationships. Significant differences were found in frequency of Ritalin (p energy drink and AmED use, as the combined effects of stimulants contained in energy drinks and the depressant effects of alcohol appear to be associated with increased non-medical prescription stimulant use. Research on the influential factors related to energy drinks, alcohol, and non-medical prescription stimulants will help practitioners to more appropriately design prevention and intervention strategies addressing these high-risk behaviors. (Am J Addict 2016;25:378-384). © 2016 American Academy of Addiction Psychiatry.

  2. Non-medical use of prescription drugs and HIV risk behaviour in transgender women in the Mid-Atlantic region of the United States.

    Science.gov (United States)

    Benotsch, Eric G; Zimmerman, Rick S; Cathers, Laurie; Pierce, Juan; McNulty, Shawn; Heck, Ted; Perrin, Paul B; Snipes, Daniel J

    2016-08-01

    Male-to-female transgender women (TGW) experience high rates of substance use and HIV. A recent substance use trend is the use of prescription medication without a doctor's consent. No research to date has examined the associations between this non-medical use of prescription drugs and HIV risk behaviour in TGW. In the present study, TGW recruited from community venues (N = 104) in the Mid-Atlantic region of the United States completed surveys assessing demographic information, non-medical use of prescription drugs, other substance use, injection practices and sexual risk behaviour. Twenty-four per cent of the sample reported lifetime non-medical use of prescription drugs across the following categories: analgesics (21.2%), anxiolytics (14.4%), stimulants (12.5%) and sedatives (8.7%). Participants reporting non-medical use of prescription drugs were more likely to report other substance use, needle use to inject drugs, injecting silicone and sharing needles. In multivariable analyses, non-medical use of prescription drugs was associated with unprotected sex, sex after engaging in substance use, and commercial sex work, after controlling for demographic factors. Self-esteem and social support from family served as protective factors for non-medical use of prescription drugs. HIV-prevention programmes focused on TGW in the United States may wish to expand their assessment of substance use to include the use of prescription medications without a physician's consent.

  3. Awareness and knowledge of common eye diseases among the academic staff (non-medical faculties) of University of Malaya.

    Science.gov (United States)

    Chew, Y K; Reddy, S C; Karina, R

    2004-08-01

    A cross sectional study was conducted to assess the level of awareness and knowledge of common eye diseases (cataract, glaucoma, diabetic retinopathy and refractive errors) among 473 academic staff (non-medical faculties) of University Malaya. The awareness of cataract was in 88.2%, diabetic retinopathy in 83.5%, refractive errors in 75.3% and glaucoma in 71.5% of the study population. The knowledge about all the above common eye diseases was moderate, except presbyopia which was poor. Multivariate analysis revealed that females, older people, and those having family history of eye diseases were significantly more aware and more knowledgeable about the eye diseases. Health education about eye diseases would be beneficial to seek early treatment and prevent visual impairment in the society.

  4. Antibiotics for acute respiratory tract infections: a mixed-methods study of patient experiences of non-medical prescriber management

    Science.gov (United States)

    Courtenay, Molly; Rowbotham, Samantha; Lim, Rosemary; Deslandes, Rhian; Hodson, Karen; MacLure, Katie; Peters, Sarah; Stewart, Derek

    2017-01-01

    Objective To (1) explore patients' expectations and experiences of nurse and pharmacist non-medical prescriber-led management of respiratory tract infections (RTIs), (2) examine whether patient expectations for antibiotics affect the likelihood of receiving them and (3) understand factors influencing patient satisfaction with RTI consultations. Design Mixed methods. Setting Primary care. Participants Questionnaires from 120 patients and follow-up interviews with 22 patients and 16 nurse and pharmacist non-medical prescribers (NMPs). Results Patients had multiple expectations of their consultation with 43% expecting to be prescribed an antibiotic. There was alignment between self-reported patient expectations and those perceived by NMPs. Patient expectations for non-antibiotic strategies, such as education to promote self-management, were associated with receipt of those strategies, whereas patient expectations for an antibiotic were not associated with receipt of these medications. ‘Patient-centred’ management strategies (including reassurance and providing information) were received by 86.7% of patients. Regardless of patients' expectations or the management strategy employed, high levels of satisfaction were reported for all aspects of the consultation. Taking concerns seriously, conducting a physical examination, communicating the treatment plan, explaining treatment decisions and lack of time restrictions were each reported to contribute to patient satisfaction. Conclusions NMPs demonstrate an understanding of patient expectations of RTI consultations and use a range of non-antibiotic management strategies, particularly those resembling a patient-centred approach. Overall, patients' expectations were met and prescribers were not unduly influenced by patient expectations for an antibiotic. Patients were satisfied with the consultation, indicating that strategies used by NMPs were acceptable. However, the lower levels of satisfaction among patients who

  5. Self-worth and coping styles of non-medical majors in medical colleges%医学院校非医学专业大学生自我价值与应对方式相关研究

    Institute of Scientific and Technical Information of China (English)

    焦桂花; 谢博; 禹玉兰; 曾家勇

    2013-01-01

    shape a healthier personality, medical colleges should try to design better courses, training goals and directions of running the optimal based on the different personality traits of medical and non-medical students.

  6. Non-medical use of opioids among HIV-infected opioid dependent individuals on opioid maintenance treatment: the need for a more comprehensive approach

    Directory of Open Access Journals (Sweden)

    Roux Perrine

    2011-11-01

    Full Text Available Abstract Background Opioid maintenance treatment (OMT has a positive impact on substance use and health outcomes among HIV-infected opioid dependent patients. The present study investigates non-medical use of opioids by HIV-infected opioid-dependent individuals treated with buprenorphine or methadone. Methods The MANIF 2000 study is a longitudinal study that enrolled a cohort of 476 HIV-infected opioid-dependent individuals. Data were collected in outpatient hospital services delivering HIV care in France. The sample comprised all patients receiving OMT (either methadone or buprenorphine who attended at least one follow-up visit with data on adherence to OMT (N = 235 patients, 1056 visits. Non-medical use of opioids during OMT was defined as having reported use of opioids in a non-medical context, and/or the misuse of the prescribed oral OMT by an inappropriate route of administration (injection or sniffing. After adjusting for the non-random assignment of OMT type, a model based on GEE was then used to identify predictors of non-medical use of opioids. Results Among the 235 patients, 144 (61.3% and 91 (38.9% patients were receiving buprenorphine and methadone, respectively, at baseline. Non-medical use of opioids was found in 41.6% of visits for 83% of individual patients. In the multivariate analysis, predictors of non-medical use of opioids were: cocaine, daily cannabis, and benzodiazepine use, experience of opioid withdrawal symptoms, and less time since OMT initiation. Conclusions Non-medical use of opioids was found to be comparable in OMT patients receiving methadone or buprenorphine. The presence of opioid withdrawal symptoms was a determinant of non-medical use of opioids and may serve as a clinical indicator of inadequate dosage, medication, or type of follow-up. Sustainability and continuity of care with adequate monitoring of withdrawal symptoms and polydrug use may contribute to reduced harms from ongoing non-medical use of opioids.

  7. Non-Medical Use of Prescription Stimulants: A Comparison of College Students and their Same-Age Peers Who Do Not Attend College.

    Science.gov (United States)

    Ford, Jason A; Pomykacz, Corey

    2016-01-01

    Data show that the prevalence of non-medical use of prescription stimulants is higher among college students than their same-age peers who do not attend college. Because of this, most of the research in this area focuses on data from samples of college students and on use motivated by academic demands. There is little research that examines whether attending college increases the odds of non-medical use of prescription stimulants while including important covariates in the analytical models. The current research addresses this gap in the literature using data from the 2013 National Survey on Drug Use and Health for respondents aged 18 to 25 years old. We estimate a multivariate logistic regression model to determine whether college attendance increased the odds of non-medical use of prescription stimulants. The analysis showed that young adults who enrolled in college full-time were more likely to report non-medical use of prescription stimulants than their same-age peers who did not attend college. There was no significant difference between part-time college students and non-college students. Future research should focus on how specific aspects of the college environment, other than academic stress, may increase the risk of non-medical use of prescription stimulants.

  8. Computer Security: oops, there it goes...

    CERN Multimedia

    Stefan Lueders, Computer Security Team

    2015-01-01

    Do you love riddles, hide and seek or picture puzzles a la “Where’s Wally”? Then take a look at the photo below, and try to spot the error.   It is hard to spot: the yellow sticker on the computer screen shows a password providing access to the web application running on the screen. Surprising! Fortunately, this sticker was quickly removed by the corresponding system owners and the password changed. However, we can all make improvements: passwords must never be written down and definitely not on stickers attached to screens, keyboards, or desks. Remember: your password is your “toothbrush” - a toothbrush you do not share and you change regularly. Neither your colleagues, your supervisor, the Service Desk or the Computer Security Team have any valid reason to ask for it. They should not and will never do so. The same is valid for any external company: UBS, Paypal, Amazon, Facebook or Google will never ask you for your pass...

  9. Pharmacology podcasts: a qualitative study of non-medical prescribing students' use, perceptions and impact on learning.

    Science.gov (United States)

    Meade, Oonagh; Bowskill, Dianne; Lymn, Joanne S

    2011-01-11

    There is growing research on student use of podcasts in academic settings. However, there is little in-depth research focusing on student experience of podcasts, in particular in terms of barriers to, and facilitators of, podcast use and students' perceptions of the usefulness of podcasts as learning tools. This study aimed to explore the experiences of non-medical prescribing students who had access to podcasts of key pharmacology lectures as supplementary learning tools to their existing course materials. Semi-structured interviews were carried out with seven non-medical prescribing students (average age = 43 years), all of whom were nurses, who had access to seven podcasts of key pharmacology lectures. These podcasts took the form of downloadable audio lecture recordings available through the virtual learning environment WebCT. Low, medium and high users of the podcasts took part in the interviews in order to access a variety of student experiences. Interview data was analysed using thematic template analysis to identify key themes surrounding student experience of podcast availability, particularly in relation to barriers to and facilitators of podcast use, and students' experiences of podcasts as a learning tool. Students used podcasts for a variety of reasons such as revisiting lectures, preparing for exams, to clarify or revise specific topics and, to a lesser extent, to catch up on a missed lecture. Barriers to podcast use centred mainly around technological issues. Lack of experience of the technology required to access podcasts proved a barrier for some students. A lack of access to suitable technology was also a reported barrier. Family assistance and I.T. assistance from the university helped facilitate students' use of the podcasts. Students found that using podcasts allowed them to have greater control over their learning and to gauge their learning needs, as well as helping them build their understanding of a complex topic. Students used podcasts for

  10. Pharmacology podcasts: a qualitative study of non-medical prescribing students' use, perceptions and impact on learning

    Directory of Open Access Journals (Sweden)

    Lymn Joanne S

    2011-01-01

    Full Text Available Abstract Background There is growing research on student use of podcasts in academic settings. However, there is little in-depth research focusing on student experience of podcasts, in particular in terms of barriers to, and facilitators of, podcast use and students' perceptions of the usefulness of podcasts as learning tools. This study aimed to explore the experiences of non-medical prescribing students who had access to podcasts of key pharmacology lectures as supplementary learning tools to their existing course materials. Methods Semi-structured interviews were carried out with seven non-medical prescribing students (average age = 43 years, all of whom were nurses, who had access to seven podcasts of key pharmacology lectures. These podcasts took the form of downloadable audio lecture recordings available through the virtual learning environment WebCT. Low, medium and high users of the podcasts took part in the interviews in order to access a variety of student experiences. Interview data was analysed using thematic template analysis to identify key themes surrounding student experience of podcast availability, particularly in relation to barriers to and facilitators of podcast use, and students' experiences of podcasts as a learning tool. Results Students used podcasts for a variety of reasons such as revisiting lectures, preparing for exams, to clarify or revise specific topics and, to a lesser extent, to catch up on a missed lecture. Barriers to podcast use centred mainly around technological issues. Lack of experience of the technology required to access podcasts proved a barrier for some students. A lack of access to suitable technology was also a reported barrier. Family assistance and I.T. assistance from the university helped facilitate students' use of the podcasts. Students found that using podcasts allowed them to have greater control over their learning and to gauge their learning needs, as well as helping them build their

  11. Pharmacology podcasts: a qualitative study of non-medical prescribing students' use, perceptions and impact on learning

    Science.gov (United States)

    2011-01-01

    Background There is growing research on student use of podcasts in academic settings. However, there is little in-depth research focusing on student experience of podcasts, in particular in terms of barriers to, and facilitators of, podcast use and students' perceptions of the usefulness of podcasts as learning tools. This study aimed to explore the experiences of non-medical prescribing students who had access to podcasts of key pharmacology lectures as supplementary learning tools to their existing course materials. Methods Semi-structured interviews were carried out with seven non-medical prescribing students (average age = 43 years), all of whom were nurses, who had access to seven podcasts of key pharmacology lectures. These podcasts took the form of downloadable audio lecture recordings available through the virtual learning environment WebCT. Low, medium and high users of the podcasts took part in the interviews in order to access a variety of student experiences. Interview data was analysed using thematic template analysis to identify key themes surrounding student experience of podcast availability, particularly in relation to barriers to and facilitators of podcast use, and students' experiences of podcasts as a learning tool. Results Students used podcasts for a variety of reasons such as revisiting lectures, preparing for exams, to clarify or revise specific topics and, to a lesser extent, to catch up on a missed lecture. Barriers to podcast use centred mainly around technological issues. Lack of experience of the technology required to access podcasts proved a barrier for some students. A lack of access to suitable technology was also a reported barrier. Family assistance and I.T. assistance from the university helped facilitate students' use of the podcasts. Students found that using podcasts allowed them to have greater control over their learning and to gauge their learning needs, as well as helping them build their understanding of a complex topic

  12. a Laboratory-Based X-Ray Phase Contrast Imaging Scanner with Applications in Biomedical and Non-Medical Disciplines

    Science.gov (United States)

    Hagen, C. K.; Diemoz, P. C.; Endrizzi, M.; Munro, P. R. T.; Szafraniec, M. B.; Millard, T. P.; Speller, R.; Olivo, D. A.

    2014-02-01

    X-ray phase contrast imaging (XPCi) provides a much higher visibility of low-absorbing details than conventional, attenuation-based radiography. This is due to the fact that image contrast is determined by the unit decrement of the real part of the complex refractive index of an object rather than by its imaginary part (the absorption coefficient), which can be up to 1000 times larger for energies in the X-ray regime. This finds applications in many areas, including medicine, biology, material testing, and homeland security. Until lately, XPCi has been restricted to synchrotron facilities due to its demanding coherence requirements on the radiation source. However, edge illumination XPCi, first developed by one of the authors at the ELETTRA Synchrotron in Italy, substantially relaxes these requirements and therefore provides options to overcome this problem. Our group has built a prototype scanner that adapts the edge-illumination concept to standard laboratory conditions and extends it to large fields of view. This is based on X-ray sources and detectors available off the shelf, and its use has led to impressive results in mammography, cartilage imaging, testing of composite materials and security inspection. This article presents the method and the scanner prototype, and reviews its applications in selected biomedical and non-medical disciplines.

  13. Image-producing procedures for non-medical applications. Benefits, risks, radiation protection; Bildgebende Verfahren im nicht medizinischen Bereich. Nutzen, Risiken, Strahlenschutz

    Energy Technology Data Exchange (ETDEWEB)

    Czarwinski, Renate [Bundesamt fuer Strahlenschutz, Berlin (Germany); Estier, Sybille [Bundesamt fuer Gesundheit (BAG), Liebefeld (Switzerland). Direktionsbereich Verbraucherschutz; Huhn, Walter [Ministerium fuer Arbeit, Integration und Soziales NRW, Duesseldorf (Germany); Lorenz, Bernd [Lorenz Consulting, Essen (Germany); Vahlbruch, Jan [Hannover Univ. (Germany). Inst. fuer Radiooekologie und Strahlenschutz (IRS); Henning, Ulrich; Michel, Rolf

    2016-05-01

    A survey is given of image-producing procedures for non-medical applications, and this under technical, juridical and radiation protection aspects. The historical development of these procedures is also described. An example is given for today's practical application.

  14. Non-medical application of radioactive materials or ionizing radiation. German legal regulations; Die Anwendung radioaktiver Stoffe oder ionisierender Strahlung ausserhalb der Medizin. Deutsche Rechtsvorschriften

    Energy Technology Data Exchange (ETDEWEB)

    Huhn, Walter [Ministerium fuer Arbeit, Integration und Soziales NRW, Duesseldorf (Germany); Lorenz, Bernd [Lorenz Consulting, Essen (Germany)

    2016-05-01

    Non-medical imaging is regulated in Germany since the 2011 radiation protection law amendment and the simultaneous X-ray regulation amendment based on the Euratom guideline 96/29. The regulations contain lists with justified and non-justified activities.

  15. WHAT ROLE SHOULD PUBLIC OPINION PLAY IN ETHICO-LEGAL DECISION MAKING? THE EXAMPLE OF SELECTING SEX FOR NON-MEDICAL REASONS USING PREIMPLANTATION GENETIC DIAGNOSIS.

    Science.gov (United States)

    Fovargue, Sara; Bennett, Rebecca

    2016-01-01

    In this article, we consider the prohibition on the use of preimplantation genetic diagnosis to select an embryo on the basis of its sex for non -: medical reasons. We use this as a case study to explore the role that public consultations have and should play in ethico-legal decision-making. Until the Human Fertilisation and Embryology Act 1990 was amended by the Human Fertilisation and Embryology Act 2008, non-medical sex selection of an embryo was not statutorily regulated, but it was the policy of the Human Fertilisation and Embryology Authority that such selection should not occur. However, since 2009, it has been a criminal offence to select an embryo on the basis of its sex for non-medical reasons. We consider the reasons given for this change and explore the role that 'public opinion' had in the decision-making process. On the face of it, asking the public what they think seems reasonable, fair and democratic, and those who are not in favour of public consultations being accorded great weight in matters of policy may appear out of touch and as wanting to impose their moral views on the public at large. But there are problems with doing so, especially when seeking to regulate ethically controversial issues. We discuss whether regulation should be influenced by public opinion obtained via 'public consultations', and utilise sex selection for non-medical reasons as an example of how (apparently) public opinion was used to support the criminalisation of this practice.

  16. The Role of Traumatic Event History in Non-Medical Use of Prescription Drugs among a Nationally Representative Sample of US Adolescents

    Science.gov (United States)

    McCauley, Jenna L.; Danielson, Carla Kmett; Amstadter, Ananda B.; Ruggiero, Kenneth J.; Resnick, Heidi S.; Hanson, Rochelle F.; Smith, Daniel W.; Saunders, Benjamin E.; Kilpatrick, Dean G.

    2010-01-01

    Background: Building on previous research with adolescents that examined demographic variables and other forms of substance abuse in relation to non-medical use of prescription drugs (NMUPD), the current study examined potentially traumatic events, depression, posttraumatic stress disorder (PTSD), other substance use, and delinquent behavior as…

  17. Associations Between the Big Five Personality Traits and the Non-Medical Use of Prescription Drugs for Cognitive Enhancement.

    Science.gov (United States)

    Sattler, Sebastian; Schunck, Reinhard

    2015-01-01

    While the number of studies of the non-medical use of prescription drugs to augment cognitive functions is growing steadily, psychological factors that can potentially help explain variance in such pharmaceutical cognitive enhancement (CE) behavior are often neglected in research. This study investigates the association between the Big Five personality traits and a retrospective (prior CE-drug use) as well as a prospective (willingness to use CE drugs) measure of taking prescription drugs with the purpose of augmenting one's cognitive functions (e.g., concentration, memory, or vigilance) without medical necessity. We use data from a large representative survey of German employees (N = 6454, response rate = 29.8%). The Five Factor Model (FFM) of Personality was measured with a short version of the Big Five Personality Traits Inventory (BFI-S), which includes: openness to experience, conscientiousness, extraversion, agreeableness, and neuroticism. Together with this, demographic variables such as gender, age, education, and income were used as potential confounders in multiple logistic regression models. Our results show a 2.96% lifetime prevalence of CE-drug use and a 10.45% willingness to (re)use such drugs in the future. We found that less conscientious and more neurotic respondents have a higher probability of prior CE-drug use and a greater willingness to use CE drugs in the future. No significant effects were found for openness, extraversion, or agreeableness. Prior CE-drug use was strongly associated with a greater willingness to take such drugs in the future. This study shows that specific personality traits are not only associated with prior enhancement behavior, but also affect the willingness to (re)use such drugs. It helps increase understanding of the risk factors of CE-drug use, which is a health-related behavior that can entail severe side-effects for consumers. The knowledge gathered can thus help improve interventions aimed at minimizing health

  18. Temporal trends in marijuana attitudes, availability and use in Colorado compared to non-medical marijuana states: 2003-11.

    Science.gov (United States)

    Schuermeyer, Joseph; Salomonsen-Sautel, Stacy; Price, Rumi Kato; Balan, Sundari; Thurstone, Christian; Min, Sung-Joon; Sakai, Joseph T

    2014-07-01

    In 2009, policy changes were accompanied by a rapid increase in the number of medical marijuana cardholders in Colorado. Little published epidemiological work has tracked changes in the state around this time. Using the National Survey on Drug Use and Health, we tested for temporal changes in marijuana attitudes and marijuana-use-related outcomes in Colorado (2003-11) and differences within-year between Colorado and thirty-four non-medical-marijuana states (NMMS). Using regression analyses, we further tested whether patterns seen in Colorado prior to (2006-8) and during (2009-11) marijuana commercialization differed from patterns in NMMS while controlling for demographics. Within Colorado those reporting "great-risk" to using marijuana 1-2 times/week dropped significantly in all age groups studied between 2007-8 and 2010-11 (e.g. from 45% to 31% among those 26 years and older; p=0.0006). By 2010-11 past-year marijuana abuse/dependence had become more prevalent in Colorado for 12-17 year olds (5% in Colorado, 3% in NMMS; p=0.03) and 18-25 year olds (9% vs. 5%; p=0.02). Regressions demonstrated significantly greater reductions in perceived risk (12-17 year olds, p=0.005; those 26 years and older, p=0.01), and trend for difference in changes in availability among those 26 years and older and marijuana abuse/dependence among 12-17 year olds in Colorado compared to NMMS in more recent years (2009-11 vs. 2006-8). Our results show that commercialization of marijuana in Colorado has been associated with lower risk perception. Evidence is suggestive for marijuana abuse/dependence. Analyses including subsequent years 2012+ once available, will help determine whether such changes represent momentary vs. sustained effects. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  19. Temporal trends in marijuana attitudes, availability and use in Colorado compared to non-medical marijuana states: 2003-2011*

    Science.gov (United States)

    Schuermeyer, Joseph; Salomonsen-Sautel, Stacy; Price, Rumi Kato; Balan, Sundari; Thurstone, Christian; Min, Sung-Joon; Sakai, Joseph T.

    2014-01-01

    Background In 2009, policy changes were accompanied by a rapid increase in the number of medical marijuana cardholders in Colorado. Little published epidemiological work has tracked changes in the state around this time. Methods Using the National Survey on Drug Use and Health, we tested for temporal changes in marijuana attitudes and marijuana-use-related outcomes in Colorado (2003-2011) and differences within-year between Colorado and thirty-four non-medical-marijuana states (NMMS). Using regression analyses, we further tested whether patterns seen in Colorado prior to (2006-8) and during (2009-11) marijuana commercialization differed from patterns in NMMS while controlling for demographics. Results Within Colorado those reporting “great-risk” to using marijuana 1-2 times/week dropped significantly in all age groups studied between 2007-8 and 2010-11 (e.g. from 45% to 31% among those 26 years and older; p=0.0006). By 2010-11 past-year marijuana abuse/dependence had become more prevalent in Colorado for 12-17 year olds (5% in Colorado, 3% in NMMS; p=0.03) and 18-25 year olds (9% vs. 5%; p=0.02). Regressions demonstrated significantly greater reductions in perceived risk (12-17 year olds, p=0.005; those 26 years and older, p=0.01), and trend for difference in changes in availability among those 26 years and older and marijuana abuse/dependence among 12-17 year olds in Colorado compared to NMMS in more recent years (2009-11 vs. 2006-8). Conclusions Our results show that commercialization of marijuana in Colorado has been associated with lower risk perception. Evidence is suggestive for marijuana abuse/dependence. Analyses including subsequent years 2012+ once available, will help determine whether such changes represent momentary vs. sustained effects. PMID:24837585

  20. The attitude of the female students of medical and non-medical fields of studies towards the cervical cancer prophylaxis

    Directory of Open Access Journals (Sweden)

    Dominik Olejniczak

    2014-09-01

    Full Text Available Introduction: The mortality of women with cervical cancer is one of the main problems of oncology. Poland is a country with high morbidity and mortality for this type of malignancy. In 2007, the incidence was 11.8 and the mortality was 5.0 per 100.000. Despite the availability of free Pap tests and many prevention campaigns, the incidence in Poland has remained at a constantly high level for several years. This prompted us to examine the degree of knowledge of different groups of the population about prophylaxis Aim of the research: To determine the knowledge and attitudes of students towards the prevention of cervical cancer. Material and methods: The study group are students of medical and non-medical faculties, who in total accounted for a panel of 112 people. The study was conducted at two universities: the Medical University of Warsaw and Kielce University of Technology. The diagnostic survey method: the study took the form of an anonymous questionnaire consisting of 25 closed questions on cervical cancer and its prevention. To determine whether there is a relationship between the subsidiaries, we used statistical methods such as test compliance χ 2 for a confidence level of p = 0.05, and r-Pearson’s correlation coefficient. Results: Training in the medical school is associated with having more knowledge in the field of medicine. Conclusions: Although the respondents most frequently declared that the main reason for them reporting to a gynaecologist was for regular check-ups, the percentage of the response was insufficient to conclude that students appreciate the role of secondary prevention of cervical cancer.

  1. Impact of Non-medical Out-of-pocket Expenses on Families of Children With Cerebral Palsy Following Orthopaedic Surgery.

    Science.gov (United States)

    Vessey, Judith A; DiFazio, Rachel L; Strout, Tania D; Snyder, Brian D

    2017-07-24

    Limited research has been conducted on the non-medical out-of-pocket expenses (NOOPEs) incurred by families of children with chronic health conditions. The study objectives were to: 1) calculate the estimated NOOPEs incurred by families during hospitalization of their child, 2) identify predictors of high NOOPEs, and 3) assess the impact of the child's chronic health condition on the family's finances. Prospective observational study. Parents were included if their child was 3-20years old, had severe, non-ambulatory cerebral palsy (CP), and scheduled for hip or spine surgery. Parents reported all NOOPEs incurred during their child's hospitalization using the Family Expense Diary. Families completed the subscales of the Impact on Family Scale and the Assessment of Caregivers Experience with Neuromuscular Disease. Descriptive and univariate and multiple hierarchical regression models were used in the analysis. Fifty two parents participated. The total NOOPEs ranged from $193.00 to $7192.71 (M=$2001.92) per hospitalization representing an average of 4% of the family's annual earned income. Caregiver age (F=8.393, phospital (F=4.497, p=0.039) were significant predictors of high NOOPEs. The subscale scores indicated that a child's chronic health condition had a significant impact on family finances. Hospitalization is associated with numerous NOOPEs that create additional financial demands for families caring for a child with severe CP. NOOPEs should be addressed when preparing families for their children's planned hospital admissions, especially those families of CSHCN who experience significant financial impacts secondary to their children's care. Copyright © 2017 Elsevier Inc. All rights reserved.

  2. [A case management programme for women with breast cancer: results of a written survey of participating medical and non-medical networking-partners].

    Science.gov (United States)

    Büscher, C; Thorenz, A; Grochocka, A; Koch, U; Watzke, B

    2011-12-01

    Breast cancer patients are as a rule in need of a multiple sequential in-patient, day-patient and out-patient permanent treatment. The required care demands a trans-sectoral networking of all multi-professional persons involved in diagnostics, therapies, rehabilitation and aftercare. A method to develop the integration of treatment processes, as well as thereby resulting in increased effectiveness and efficiency, can constitute the concept of case management. A prerequisite for an effective implementation of case management and thus the starting point of the present survey is a well-functioning network encompassing optimal cooperation. Within the framework of the evaluation of the case management-based integrated care model "mammaNetz" for women with mamma carcinoma as a whole and against the background of the potential for innovation and improvement of case management on the one hand as well as the existence of only few empirical data otherwise, the present survey of members of a trans-sectoral network of the service centre was accomplished. Medical and non-medical networking partners of the service centre (N=168) were questioned by regular mail about different aspects of the cooperation. Identical items in both surveys were compared. The return rate for the medical networking partners is about 59% (n=35), whereby only medical network partners in private practice participated in the survey. For the non-medical networking partners about 60% (n=66) participated. Medical networking partners assess the cooperation with the service centre in reference to the exchange of information slightly more positively (66%) than the non-medical networking partners (59%). Medical networking partners are in significantly more frequent contact with the service centre and see in the cooperation significantly more advantages for their own office/facility (each with p=0.001) than non-medical networking partners. Overall the results suggest that medical as well as non-medical networking

  3. Non-medical factors affecting antenatal preferences for delivery route and actual delivery mode of women in southwestern Iran.

    Science.gov (United States)

    Rajabi, Abdolhalim; Maharlouei, Najmeh; Rezaianzadeh, Abbas; Rajaeefard, Abdolreza; Keshavarzi, Sareh; Lankarani, Kamran B; Gholami, Ali

    2016-11-01

    Assessment of the contribution of non-medical factors to mode of delivery and birth preference in Iranian pregnant women in southwestern Iran. This cohort study used data from a structured questionnaire completed in early pregnancy and information about the subsequent delivery obtained through personal contact. Women were recruited by random sampling from antenatal clinics when scheduling visits over the course of 5 weeks from December 2012 to February 2013 and were followed-up 1 month after birth. Of the 2199 women recruited, 99.63% were eligible for the study. Of the 748 women who expressed a desire to deliver their babies by cesarean section (CS) in early pregnancy, 87% had an elective cesarean section. The logistic regression analyses showed that normative beliefs (odds ratio [OR] 1.792, 95% confidence interval (1) 1.073-2.993), control beliefs (OR: 0.272, 95% CI: 0.162-0.459), and evaluation of outcomes (OR: 0.431, 95% CI: 0.268-0.692) favored the preference for cesarean section. The desire for delivery by elective cesarean section was associated with normative beliefs (OR: 1.138; 95% CI: 1.001-1.294), control beliefs (OR: 0.804; 95% CI: 0.698-0.927), and expectations about maternity care (OR: 0.772; 95% CI: 0.683-0.873), medical influences (OR: 1.150; 95% CI: 1.023-1.291), evaluation of outcome (OR: 0.789; 95% CI: 0.696-0.894), age, preference for cesarean section (OR: 5.445; 95% CI: 3.928-7.546), spouse educational level, and number of live births. A woman's preference for delivery by cesarean section influenced their subsequent mode of delivery. Asking women in early pregnancy about their preferred mode of delivery provides the opportunity to extend their supports which might reduce the rate of elective cesarean section. This decision is affected by age, spouse educational level, number of live births, and preconceived maternal attitudes about delivery.

  4. Aging related changes in mixed basal saliva concentration of sodium, potassium and chloride in healthy non medicated humans.

    Science.gov (United States)

    De Oliveira, Rui; Navas, Eunice; Duran, Carolina; Pinto, Maria; Gutierrez, Jose; Eblen-Zajjur, Antonio

    2014-01-01

    It is well known that the salivary flow is reduced by aging but ionic composition changes associated to aging have been less evaluated. To measure salivary and plasmatic [Na(+)], [K(+)] and [Cl(-)] and to correlate with age in healthy, non-medicated subjects of any gender, 165 healthy participating subjects (over 15 years old) were asked to give sample of 5 mL mix basal saliva in a plastic vial without any stimulation technique, additionally, 5 mL of venous blood was collected. Samples [Na(+)] and [K(+)] were measured by flame photometry (Corning™ M-405) and [Cl(-)] by voltametric chlorometry (Corning™ M-920). Ionic concentrations were expressed as (X±DE; meq.L⁻¹). All three ionic concentrations progressively increased with age, with the lineal regression equation being: [Na(+)] mEq=17.76 + 0.26(Age); r=+0.42; F=31.5; P=0.00001; [K(+)] mEq=13.2+0.15(Age); r=+0.32; F=16.5; P=0.00001; [Cl(-)] mEq=9.05+0.18(Age); r=+0.35; F=7.8; P=0.0071. Age induced changes in salivary ionic concentrations were not associated to blood ionic changes. However, saliva and blood [Na(+)] and [K(+)] were correlated (r=+0.25; F=4.49; P=0.04 and r=+0.30; F=6.98; P=0.01, respectively). Significant association was found among salivary ions: [Na(+)] mEq=9.14+0.99[K(+)] (r=+0.79; F=95.2; P=0.000001); [Cl(-)] mEq=0.95+0.56[Na(+)] (r=0.79; F=106.6; P=0.000001) and [Cl(-)] mEq=3.45+0.69[K(+)] (r=0.73; F=72.5; P=0.000001). These results confirm and measure the impact of aging over the mixed and resting salivary secretion process and suggest that local changes are not related to blood ionic composition.

  5. Extending the boundaries of the Declaration of Helsinki: a case study of an unethical experiment in a non-medical setting.

    Science.gov (United States)

    Richter, E D; Barach, P; Berman, T; Ben-David, G; Weinberger, Z

    2001-04-01

    To examine the ethical issues involved in governmental decisions with potential health risks, we review the history of the decision to raise the interurban speed limit in Israel in light of its impact on road death and injury. In 1993, the Israeli Ministry of Transportation initiated an "experiment" to raise the interurban speed limit from 90 to 100 kph. The "experiment" did not include a protocol and did not specify cut-off points for early termination in the case of adverse results. After the raise in the speed limit, the death toll on interurban roads rose as a result of a sudden increase in speeds and case fatality rates. The committee's decision is a case study in unfettered human experimentation and public health risks when the setting is non-medical and lacks a defined ethical framework. The case study states the case for extending Helsinki type safeguards to experimentation in non-medical settings.

  6. The global diversion of pharmaceutical drugs
non-medical use and diversion of psychotropic prescription drugs in North America: a review of sourcing routes and control measures.

    Science.gov (United States)

    Fischer, Benedikt; Bibby, Meagan; Bouchard, Martin

    2010-12-01

    North America features some of the world's highest consumption levels for controlled psychoactive prescription drugs (PPDs; e.g. prescription opioids, benzodiazepines, stimulants), with non-medical use and related harms (e.g. morbidity, mortality) rising in key populations in recent years. While the determinants, characteristics and impacts of these 'use' problems are increasingly well documented, little is known about the 'supply' side of non-medical PPD use, much of which is facilitated by 'diversion' as a key sourcing route. This paper provides a select review of the phenomenon of PPD diversion in North America, also considering interventions and policy implications. A conceptual and empirical review of select-peer- and non-peer-reviewed research literature from 1991 to 2010 focusing upon PPD diversion in North America was conducted. The phenomenon of PPD diversion is heterogeneous. Especially among general populations, a large proportion of PPDs for non-medical use are obtained from friends or family members. Other PPD diversion routes involve 'double doctoring' or 'prescription shopping'; street drug markets; drug thefts, prescription forgeries or fraud; as well as PPD purchases from the internet. The distinct nature and heterogeneity make PPD diversion a complex and difficult target for interventions. Prescription monitoring programs (PMPs) appear to reduce overall PPD use, yet their impact on reducing diversion or non-medical use is not clear. Law enforcement is unlikely to reach PPD diversion effectively. Effective reduction will probably require reductions in overall PPD consumption volumes, although such will need to be accomplished without compromising standards of good medical (e.g. pain) care. © 2010 The Authors, Addiction © 2010 Society for the Study of Addiction.

  7. Knowledge and awareness about breast cancer and its early symptoms among medical and non-medical students of Southern Punjab, Pakistan.

    Science.gov (United States)

    Noreen, Mamoona; Murad, Sheeba; Furqan, Muhammad; Sultan, Aneesa; Bloodsworth, Peter

    2015-01-01

    Breast cancer is the leading cause of morbidity and mortality globally but has an even more significant impact in developing countries. Pakistan has the highest prevalence among Asian countries. A general lack of public awareness regarding the disease often results in late diagnosis and poor treatment outcomes. The literacy rate of the Southern Punjab (Pakistan) is low compared to its Northern part. It is therefore vital that university students and especially medical students develop a sound knowledge about the disease so that they can spread awareness to others who may be less educated. This study therefore considers current knowledge and understanding about the early signs of breast cancer amongst a study group of medical and non-medical university students of the Southern Punjab, Pakistan. A cross-sectional descriptive analysis of the university students was carried out using a self-administered questionnaire to assess their awareness of breast cancer from March to May 2014. A total of 566 students participated in this study, out of which 326 were non-medical and 240 were from a medical discipline. Statistical analysis was carried out using Graph Pad Prism Version 5 with a significance level set at pstudents were aware of the early warning signs of the breast cancer development. Knowledge of medical students about risk factors was significantly better than the non medical ones, but on the whole was insufficient. Our study indicated that knowledge regarding breast cancer was generally insufficient amongst the majority of the university students (75% non-medical and 55% medical) of Southern Punjab, Pakistan. This study highlights the need to formulate an awareness campaign and to organize conferences to promote breast cancer awareness among students in this region.

  8. Roles of the non-medical prescribing leads within organisations across a Strategic Health Authority: perceived functions and factors supporting the role.

    Science.gov (United States)

    Lim, Rosemary Hwee Mei; Courtenay, Molly; Fleming, Gail

    2013-04-01

    Extending the roles of nurses, pharmacists and allied health professionals to include prescribing has been identified as one way of improving service provision. In the UK, over 50 000 non-medical healthcare professionals are now qualified to prescribe. Implementation of non-medical prescribing ( NMP) is crucial to realise the potential return on investment. The UK Department of Health recommends a NMP lead to be responsible for the implementation of NMP within organisations. The aim of this study was to explore the role of NMP leads in organisations across one Strategic Health Authority (SHA) and to inform future planning with regards to the criteria for those adopting this role, the scope of the role and factors enabling the successful execution of the role. Thirty-nine NMP leads across one SHA were approached. Semi-structured telephone interviews were conducted. Issues explored included the perceived role of the NMP lead, safety and clinical governance procedures and facilitators to the role. Transcribed audiotapes were coded and analysed using thematic analytical techniques. In total, 27/39 (69.2%) NMP leads were interviewed. The findings highlight the key role that the NMP lead plays with regards to the support and development of NMP within National Health Service trusts. Processes used to appoint NMP leads lacked clarity and varied between trusts. Only two NMP leads had designated or protected time for their role. Strategic influence, operational management and clinical governance were identified as key functions. Factors that supported the role included organisational support, level of influence and dedicated time. The NMP lead plays a significant role in the development and implementation of NMP. Clear national guidance is needed with regards to the functions of this role, the necessary attributes for individuals recruited into this post and the time that should be designated to it. This is important as prescribing is extended to include other groups of

  9. Enforcement actions: Significant actions resolved material licensees (non-medical). Volume 14, No. 1, Part 3, Quarterly progress report, January--March 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-05-01

    This compilation summarizes significant enforcement actions that have been resolved during one quarterly period (January--March 1995) and includes copies of letters, Notices, and Orders sent by the Nuclear Regulatory Commission to Material Licensees (non-Medical) with respect to these enforcement actions. It is anticipated that the information in this publication will be widely disseminated to managers and employees engaged in activities licensed by the NRC, so that actions can be taken to improve safety by avoiding future violations similar to those described in this publication.

  10. [Artificial illness as a result of non-medical use of anabolic androgenic steroids: A case report and a review of literature].

    Science.gov (United States)

    Povzun, S A

    2016-01-01

    A 42-year-old female body builder who had used anabolic androgenic steroids (AASs) for 18 years to build up muscle mass died from liver rupture. The cause of the latter was multiple abscesses caused by Actinomyces, which developed in the presence of immunodeficiency. The postmortem changes in different organs were due to hormonal imbalance. The paper gives the data available in the literature pertaining to the analysis of the effects of AASs taken in supraphysiological doses on the body and their non-medical application.

  11. Pharmacology as a foreign language: a preliminary evaluation of podcasting as a supplementary learning tool for non-medical prescribing students.

    Science.gov (United States)

    Meade, Oonagh; Bowskill, Dianne; Lymn, Joanne S

    2009-12-18

    Nurses and other health professionals in the U.K. can gain similar prescribing rights to doctors by undertaking a non-medical prescribing course. Non-medical prescribing students must have a thorough understanding of the pharmacology of prescribing to ensure safe practice. Pharmacology education at this level is complicated by the variation in students' prior subject knowledge of, and anxiety about, the subject. The recent advances in technology, particularly the potential for mobile learning, provide increased opportunities for students to familiarise themselves with lecture materials and hence promote understanding. The objective of this study was therefore to evaluate both the subjective (student perception) and objective (student use and exam results) usefulness of podcasts of pharmacology lectures which were provided as an extra learning tool to two cohorts (n = 69) of non-medical prescribing students. The podcasts were made available to students through the virtual learning environment WebCT. Use of podcasts by two successive cohorts of nurse prescribing students (n = 69) was tracked through WebCT. Survey data, which was collected from 44 of these students, investigated patterns of/reasons for podcast use and perceived usefulness of podcasts as a learning tool. Of these 69 students, 64 completed the pharmacology exam. In order to examine any impact of podcasts on student knowledge, their exam results were compared with those of two historical cohorts who did not have access to podcasts (n = 70). WebCT tracking showed that 91% of students accessed at least one podcast. 93% of students used the podcasts to revisit a lecture, 85% used podcasts for revision, and 61% used the podcasts when they had a specific question. Only 22% used the podcasts because they had missed a pharmacology session. Most students (81%) generally listened to the entire podcast rather than specific sections and most (73%) used them while referring to their lecture handouts. The majority of

  12. Pharmacology as a foreign language: A preliminary evaluation of podcasting as a supplementary learning tool for non-medical prescribing students

    Directory of Open Access Journals (Sweden)

    Lymn Joanne S

    2009-12-01

    Full Text Available Abstract Background Nurses and other health professionals in the U.K. can gain similar prescribing rights to doctors by undertaking a non-medical prescribing course. Non-medical prescribing students must have a thorough understanding of the pharmacology of prescribing to ensure safe practice. Pharmacology education at this level is complicated by the variation in students' prior subject knowledge of, and anxiety about, the subject. The recent advances in technology, particularly the potential for mobile learning, provide increased opportunities for students to familiarise themselves with lecture materials and hence promote understanding. The objective of this study was therefore to evaluate both the subjective (student perception and objective (student use and exam results usefulness of podcasts of pharmacology lectures which were provided as an extra learning tool to two cohorts (n = 69 of non-medical prescribing students. Methods The podcasts were made available to students through the virtual learning environment WebCT. Use of podcasts by two successive cohorts of nurse prescribing students (n = 69 was tracked through WebCT. Survey data, which was collected from 44 of these students, investigated patterns of/reasons for podcast use and perceived usefulness of podcasts as a learning tool. Of these 69 students, 64 completed the pharmacology exam. In order to examine any impact of podcasts on student knowledge, their exam results were compared with those of two historical cohorts who did not have access to podcasts (n = 70. Results WebCT tracking showed that 91% of students accessed at least one podcast. 93% of students used the podcasts to revisit a lecture, 85% used podcasts for revision, and 61% used the podcasts when they had a specific question. Only 22% used the podcasts because they had missed a pharmacology session. Most students (81% generally listened to the entire podcast rather than specific sections and most (73% used them while

  13. Extending the boundaries of the Declaration of Helsinki: a case study of an unethical experiment in a non-medical setting

    Science.gov (United States)

    Richter, E.; Barach, P.; Berman, T.; Ben-David, G; Weinberger, Z.

    2001-01-01

    To examine the ethical issues involved in governmental decisions with potential health risks, we review the history of the decision to raise the interurban speed limit in Israel in light of its impact on road death and injury. In 1993, the Israeli Ministry of Transportation initiated an "experiment" to raise the interurban speed limit from 90 to 100 kph. The "experiment" did not include a protocol and did not specify cut-off points for early termination in the case of adverse results. After the raise in the speed limit, the death toll on interurban roads rose as a result of a sudden increase in speeds and case fatality rates. The committee's decision is a case study in unfettered human experimentation and public health risks when the setting is non-medical and lacks a defined ethical framework. The case study states the case for extending Helsinki type safeguards to experimentation in non-medical settings. Key Words: Declaration of Helsinki • human experimentation • speed limit PMID:11314157

  14. Non-medical use of methylphenidate: a review Uso não terapêutico do metilfenidato: uma revisão

    Directory of Open Access Journals (Sweden)

    Luana Freese

    2012-01-01

    Full Text Available INTRODUCTION: Methylphenidate is a psychostimulant medication used for the treatment of attention deficit hyperactivity disorder and narcolepsy. However, it has also been used for non-medical purposes, e.g. to produce euphoria, to increase self-esteem, and to achieve the so-called neurocognitive enhancement, decreasing the feeling of tiredness and increasing focus and attention. OBJECTIVE: To describe, from theoretical and contextual points of view, the potential for abuse and non-medical use of methylphenidate. METHOD: The PubMed, SciELO and Cochrane databases were searched using the following keywords in Portuguese: metilfenidato, transtorno do déficit de atenção com hiperatividade, facilitadores dos processos cognitivos or agentes nootrópicos, and abuso de substâncias; and in English: methylphenidate, attention deficit disorder with hyperactivity, cognitive enhancement or nootropic agents, and substance abuse. Studies published between 1990 and 2010 were selected for review. RESULTS: Non-medical use of methylphenidate is a relevant topic that raises important ethical and scientific questions in several areas, e.g. pharmacological and neurobiological characteristics, evidence of methylphenidate use, forms of non-medical use of methylphenidate, mechanisms of action, and therapeutic application of methylphenidate. According to the review, methylphenidate can generally influence performance as a result of its stimulatory effect. Notwithstanding, evidence does not support the conclusion that it can enhance cognitive performance. CONCLUSION: Health professionals need to acquire expert knowledge and inform patients and their families on the methylphenidate potential for abuse when used with non-medical purposes.INTRODUÇÃO: O metilfenidato é um medicamento psicoestimulante usado no tratamento do transtorno de déficit de atenção e hiperatividade e da narcolepsia. No entanto, a droga também vem sendo utilizada com fins não terap

  15. Concurrent versus simultaneous use of alcohol and non-medical use of prescription drugs: is simultaneous use worse for mental, social, and health issues?

    Science.gov (United States)

    Baggio, Stéphanie; Deline, Stéphane; Studer, Joseph; N'Goran, Alexandra; Mohler-Kuo, Meichun; Daeppen, Jean-Bernard; Gmel, Gerhard

    2014-01-01

    Abstract This study investigated the difference between concurrent and simultaneous use of alcohol and non-medical use of prescription drugs (NMUPD) in relation to mental, social, and health issues. The 544 study participants of the Swiss ongoing Cohort Study on Substance Use Risk Factors (C-SURF) had a combined use of alcohol with NMUPD during the previous 12 months. Alcohol-related problems (i.e., dependence and consequences), as well as mental, social, and health concerns (i.e., depression, general mental/physical health, and social/health consequences), were assessed. The simultaneous use of alcohol and NMUPD proved to be a greater risk factor for mental, social, and health issues than concurrent use. This study adds information regarding simultaneous polydrug use, which results in distinct effects compared to concurrent use, including important social, psychosocial, and health-related consequences.

  16. Egg freezing for non-medical uses: the lack of a relational approach to autonomy in the new Israeli policy and in academic discussion.

    Science.gov (United States)

    Shkedi-Rafid, Shiri; Hashiloni-Dolev, Yael

    2012-03-01

    Recently, the Israel National Bioethics Council (INBC) issued recommendations permitting egg freezing to prevent both disease- and age-related fertility decline. The INBC report forms the basis of Israel's new policy, being one of the first countries to regulate and authorise egg freezing for what it considers to be non-medical (ie, social) uses. The ethical discussion in the INBC report is reviewed and compared with the scant ethical discourse in the academic literature on egg freezing as a means of preventing age-related loss of fertility. We argue that both the INBC recommendations and the bioethical academic discourse on egg freezing are grounded in liberal ideology, which views technology as primarily enabling. Accordingly, they promote 'individual autonomy' as exercised through informed consent. Our study suggests that a relational approach to autonomy may be a more suitable model for considering women's choices about egg freezing.

  17. Sequential pattern of non-medical drug use in the drug career of opiate dependents in Nagpur, India.

    Science.gov (United States)

    Wairagkar, N S; Wahab, S N; Kulkarni, H R

    1996-12-01

    A study was carried out in a group of opiate addicts who reported to various centers in Nagpur city, India, to know the sequential pattern of nonmedical drug use in the drug career of opiate dependents in Nagpur. The mean age of the study group was 28.2 years, the majority were males, educated up to 10th standard, employed in various occupations like petty business, vehicle driving, etc, with an average monthly income of Rs. 316. The average number of drugs ever used per person was 3.7 +/- 1.2, those recently used was 2.6 +/- 0.9 and currently used was 2.2 +/- 0.6. The study group experienced 13 drug types in their addict careers. Beedi¿cigarette was the first drug abused by the majority. Drug careers starting with beedi¿cigarette, progressing to alcohol and then to canabis and finally to heroin were observed in a majority of subjects. There appeared to be a shift from multidrug use to the singular combination of heroin and beedi¿cigarette currently. Use of all other drugs declined in favor of heroin as the career progressed. The study indicates that preventive programs should be directed at reducing the use of initial drugs like beedi¿cigarette and alcohol and also reducing the social acceptability of these drugs as measure for preventing progression to hard drugs like heroin.

  18. Analysis of the Cochrane Review: Non-medical Prescribing versus Medical Prescribing for Acute and Chronic Disease Management in Primary and Secondary Care. Cochrane Database Syst Ver. 2016;11:CD011227.

    Directory of Open Access Journals (Sweden)

    Gonçalo Silva Duarte

    2017-01-01

    of evidence, among others. Prescription by pharmacists and nurses with different levels of undergraduate, specific and postgraduate education could provide comparable outcomes to medical prescription, specifically with regards to adherence to therapy, adverse events, overall satisfaction, quality of life, and resource utilisation (hospitalisations, visits to the emergency department, and consultations. Non-medical prescribers frequently had medical support available to facilitate a collaborative practice. With appropriate training and support, non-medical prescription by nurses and pharmacists can be as effective as when carried out by doctors.

  19. Inter-Rater Reliability of Historical Data Collected by Non-Medical Research Assistants and Physicians in Patients with Acute Abdominal Pain

    Directory of Open Access Journals (Sweden)

    Mills, Angela M

    2009-02-01

    Full Text Available OBJECTIVES: In many academic emergency departments (ED, physicians are asked to record clinical data for research that may be time consuming and distracting from patient care. We hypothesized that non-medical research assistants (RAs could obtain historical information from patients with acute abdominal pain as accurately as physicians.METHODS: Prospective comparative study conducted in an academic ED of 29 RAs to 32 resident physicians (RPs to assess inter-rater reliability in obtaining historical information in abdominal pain patients. Historical features were independently recorded on standardized data forms by a RA and RP blinded to each others' answers. Discrepancies were resolved by a third person (RA who asked the patient to state the correct answer on a third questionnaire, constituting the "criterion standard." Inter-rater reliability was assessed using kappa statistics (kappa and percent crude agreement (CrA.RESULTS: Sixty-five patients were enrolled (mean age 43. Of 43 historical variables assessed, the median agreement was moderate (kappa 0.59 [Interquartile range 0.37-0.69]; CrA 85.9% and varied across data categories: initial pain location (kappa 0.61 [0.59-0.73]; CrA 87.7%, current pain location (kappa 0.60 [0.47-0.67]; CrA 82.8%, past medical history (kappa 0.60 [0.48-0.74]; CrA 93.8%, associated symptoms (kappa 0.38 [0.37-0.74]; CrA 87.7%, and aggravating/alleviating factors (kappa 0.09 [-0.01-0.21]; CrA 61.5%. When there was disagreement between the RP and the RA, the RA more often agreed with the criterion standard (64% [55-71%] than the RP (36% [29-45%].CONCLUSION: Non-medical research assistants who focus on clinical research are often more accurate than physicians, who may be distracted by patient care responsibilities, at obtaining historical information from ED patients with abdominal pain.

  20. Economic burden to primary informal caregivers of hospitalized older adults in Mexico: a cohort study

    Science.gov (United States)

    2013-01-01

    Background The burden of out of pocket spending for the Mexican population is high compared to other countries. Even patients insured by social security institutions have to face the cost of health goods, services or nonmedical expenses related to their illness. Primary caregivers, in addition, experience losses in productivity by taking up responsibilities in care giving activities. This situation represents a mayor economic burden in an acute care setting for elderly population. There is evidence that specialized geriatric services could represent lower overall costs in these circumstances and could help reduce these burdens. The aim of this study was to investigate economic burden differences in caregivers of elderly patients comparing two acute care services (Geriatric and Internal Medicine). Specifically, economic costs associated with hospitalization of older adults in these two settings by evaluating health care related out of pocket expenditures (OOPE), non-medical OOPE and indirect costs. Methods A comparative analysis of direct and indirect costs in hospitalised elderly patients (60-year or older) and their primary informal caregivers in two health care settings, using a prospective cohort was performed. Economic burden was measured by out of pocket expenses and indirect costs (productivity lost) due to care giving activities. The analysis included a two-part model, the first one allowing the estimation of the probability of observing any health care related and non-medical OOPE; and the second one, the positive observations or expenditures. Results A total of 210 subjects were followed during their hospital stay. Of the total number of subjects 95% reported at least one non-medical OOPE, being daily transportation the most common expense. Regarding medical OOPE, medicines were the most common expense, and the mean numbers of days without income were 4.12 days. Both OOPE and indirect costs were significantly different between type of services, with less

  1. Economic burden to primary informal caregivers of hospitalized older adults in Mexico: a cohort study.

    Science.gov (United States)

    López-Ortega, Mariana; García-Peña, Carmen; Granados-García, Víctor; García-González, José Juan; Pérez-Zepeda, Mario Ulises

    2013-02-08

    The burden of out of pocket spending for the Mexican population is high compared to other countries. Even patients insured by social security institutions have to face the cost of health goods, services or nonmedical expenses related to their illness. Primary caregivers, in addition, experience losses in productivity by taking up responsibilities in care giving activities. This situation represents a mayor economic burden in an acute care setting for elderly population. There is evidence that specialized geriatric services could represent lower overall costs in these circumstances and could help reduce these burdens.The aim of this study was to investigate economic burden differences in caregivers of elderly patients comparing two acute care services (Geriatric and Internal Medicine). Specifically, economic costs associated with hospitalization of older adults in these two settings by evaluating health care related out of pocket expenditures (OOPE), non-medical OOPE and indirect costs. A comparative analysis of direct and indirect costs in hospitalised elderly patients (60-year or older) and their primary informal caregivers in two health care settings, using a prospective cohort was performed. Economic burden was measured by out of pocket expenses and indirect costs (productivity lost) due to care giving activities. The analysis included a two-part model, the first one allowing the estimation of the probability of observing any health care related and non-medical OOPE; and the second one, the positive observations or expenditures. A total of 210 subjects were followed during their hospital stay. Of the total number of subjects 95% reported at least one non-medical OOPE, being daily transportation the most common expense. Regarding medical OOPE, medicines were the most common expense, and the mean numbers of days without income were 4.12 days. Both OOPE and indirect costs were significantly different between type of services, with less overall economic burden to

  2. The mediating effects of depressive symptoms and sleep quality on the relationship between the non-medical use of prescription drugs and suicidal behaviors among Chinese adolescents.

    Science.gov (United States)

    Wang, Juan; Xu, Yan; Guo, Lan; Deng, Jian-Xiong; Huang, Jing-Hui; Huang, Guo-Liang; Gao, Xue; Wu, Hong; Pan, Si-Yuan; Lu, Ci-Yong

    2017-09-01

    The nature of the relationship between the non-medical use of prescription drugs (NMUPD) and suicide has not been clearly elucidated. Some studies have suggested that the relationship between substance use and suicidal ideation may be spurious and could be explained by other variables. A school-based cross-sectional study was performed in Guangzhou. A total of 5853 students completed questionnaires and were included in the study. NMUPD, alcohol use, illicit drug use, depressive symptoms, sleep quality, and suicidal behaviors were assessed. The mediating effects of depressive symptoms and sleep quality on the relationship between NMUPD and suicidal behaviors were examined using a structural equation model. In the simple model without mediation, a positive relationship between NMUPD and suicidal behaviors in adolescents was found, which was independent of effects from the use of other substances. Both depressive symptoms and sleep quality were significant mediators of this relationship. Public health and educational professionals should survey depressive symptoms and sleep quality and provide interventions when managing suicidal behaviors among adolescents engaging in NMUPD. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Association of knowledge of HIV and other factors with individuals' attitudes toward HIV infection: a national cross-sectional survey among the Japanese non-medical working population.

    Directory of Open Access Journals (Sweden)

    Guoqin Wang

    Full Text Available BACKGROUND: The stigma of and discrimination because of HIV has been described as the most important obstacle to prevention and treatment efforts. The purpose of this study was to investigate negative attitudes and prejudice toward HIV among the Japanese non-medical working population and to explore contributing factors. METHODS: An online anonymous nationwide survey involving approximately 3,000 individuals was conducted in Japan. Questions ranged from background information and HIV knowledge to individuals' attitudes towards HIV infection in the workplace. Descriptive statistics and logistic regression were applied for analysis. RESULTS: Thirty-three percent of participants feared transmission of HIV from infected colleagues, 34% tended to avoid contact with them and 40% had prejudiced opinions about HIV infection. Despite a relatively high level of knowledge of HIV/AIDS overall (11.9 ± 3.3 from 15 points, only 50% of individuals were aware of some issues. Greater knowledge was associated with less negative attitudes towards HIV infection (OR 0.39, 95% CI 0.31-0.48 for prejudiced opinion, high compared with low level of knowledge, whereas greater health consciousness was inversely related to attitude (OR 1.97, 95% CI 1.50-2.58 for prejudiced opinion, high compared with low health consciousness. CONCLUSION: Knowledge neutralizes peoples' negative attitudes towards HIV infection, whereas greater health consciousness may worsen them. Educational programs should balance knowledge with health consciousness to improve the efficacy of HIV interventions.

  4. THE INFLUENCE OF COMBINATION NON-MEDICAL TREATMENT INCLUDING FUNCTIONAL PROGRAMMED ELECTRICAL STIMULATION ON THE CLINICAL AND INSTRUMENTAL PARAMETERS IN PATIENTS WITH CEREBRAL PALSY WITH SPASTIC DIPLEGIA

    Directory of Open Access Journals (Sweden)

    V. V. Eliseev

    2015-01-01

    Full Text Available Background: Cerebral palsy is the leading cause of physical disability in pediatric  age. The search for new methods and improvement of old rehabil- itation techniques is ongoing, due to low efficacy of the latter. Aim: To assess the efficacy of a func- tional programmed electrical muscle stimulation as a part  of combination treatment of patients with cerebral palsy in the form of spastic diplegia. Materials and methods: We analyzed the results of treatment of 71 children with cerebral palsy and spastic diplegia, who had  been  randomized  into two groups  depending on the type of treatment. In  the  first group,  the  patients  (n = 38 received a course of functional programmed electric stim- ulation  in combination with  other  non-medical treatment  methods.  The  second   group   (n = 33 underwent a usual  course  of electrical  stimula- tion in combination with non-medical  treatment, similar to that  in the first group. The third group (control   included   41   children   without    cere- bral palsy. Clinical and  instrumental parameters were  assessed  in all study  participants. Results: After the course of combination treatment in the group  1, the  tonus  of m. gastrocnemius was de- creased significantly by 41%, that of the posterior group  of femur muscles by 43%, adductor group of femur muscles by 36%. In the group  2, the re- spective parameters decreased by 24, 21 and 21%. Muscle power  endurance was  increased  signifi- cantly in patients of both groups: that of long back extensors by 12.5 and 6.2 sec, of m. rectus abdomi- nis by 10.6 sec and 5.2 sec, of gluteal muscles by 9.3 and 4.6 sec, of m. quadriceps  by 19.8 and 7.2 sec, of m. anterior  tibialis by 12.1 and 4.6 sec, respec- tively. After the  treatment, the  active movement volume in the large joints of lower extremities  in the group 1 patients  improved as follows: by 15.6° in hip joints, by 11.1° in knee joints and by

  5. A league of their own: demographics, motivations and patterns of use of 1,955 male adult non-medical anabolic steroid users in the United States

    Directory of Open Access Journals (Sweden)

    Darkes Jack

    2007-10-01

    Full Text Available Abstract Background Rule violations among elite-level sports competitors and tragedies among adolescents have largely defined the issue of non-medical anabolic-androgenic steroid (NMAAS use for the public and policy makers. However, the predominant and oft-ignored segment of the NMAAS community exists in the general population that is neither participating in competitive sports nor adolescent. A clearer profile of NMAAS users within the general population is an initial step in developing a full understanding of NMAAS use and devising appropriate policy and interventions. This survey sought to provide a more comprehensive profile of NMAAS users by accessing a large sample of user respondents from around the United States. Methods U.S.-based male NMAAS users (n = 1955 were recruited from various Internet websites dedicated to resistance training activities and use of ergogenic substances, mass emails, and print media to participate in a 291-item web-based survey. The Internet was utilized to provide a large and geographically diverse sample with the greatest degree of anonymity to facilitate participation. Results The majority of respondents did not initiate AAS use during adolescence and their NMAAS use was not motivated by athletics. The typical user was a Caucasian, highly-educated, gainfully employed professional approximately 30 years of age, who was earning an above-average income, was not active in organized sports, and whose use was motivated by increases in skeletal muscle mass, strength, and physical attractiveness. These findings question commonly held views of the typical NMAAS user and the associated underlying motivations. Conclusion The focus on "cheating" athletes and at risk youth has led to ineffective policy as it relates to the predominant group of NMAAS users. Effective policy, prevention or intervention should address the target population(s and their reasons for use while utilizing their desire for responsible use and

  6. Gene expression profiling within the spleen of Clostridium perfringens-challenged Broilers fed antibiotic-medicated and non-medicated diets

    Directory of Open Access Journals (Sweden)

    Yu Hai

    2009-06-01

    Full Text Available Abstract Background Clostridium perfringens (Cp is a Gram-positive anaerobic bacterium that causes necrotic enteritis (NE in poultry when it overgrows in the small intestine. NE disease has previously been controlled through the use of growth-promoting antibiotics. This practice was recently banned in European countries, leading to significantly increased incidence of NE threatening the poultry industry. Control strategies and technology as substitutes to dietary antibiotics are therefore urgently required. To develop the substitutes, it is important to understand host immune responses to Cp infection. However, the knowledge is still lacking. We therefore investigated gene expression profiles within immunologically-relevant tissue, the spleen, in order to identify factors that are involved in immunity to NE and have potential as therapeutic targets. Results Use of a 44 K Agilent chicken genome microarray revealed significant up-regulation of many immune-associated genes in Cp-challenged chickens, including galectin 3, IFNAR1, IgY-receptor, TCRγ, granzyme A, and mannose-6-P-R, which were subsequently validated by quantitative PCR assays. Functional annotation of differentially expressed genes was conducted using the High Throughput Gene Ontology Functional Annotation database. Medicated and Non-medicated chickens had similar annotation profiles with cell activities and regulation being the most dominant biological processes following Cp infection. Conclusion Broiler chickens demonstrated an intricate and holistic magnitude of host response to Cp challenge and the development of NE. Although the influence of dietary antibiotics appeared to be less significant than the disease process, both had a considerable impact on the host response. Markers previously identified in intestinal inflammatory diseases of other species, including humans, and indicators of enhanced antibody responses, appeared to be involved in the chicken response to Cp challenge

  7. Topical, Non-Medicated LOYON(®) in Facilitating the Removal of Scaling in Infants and Children with Cradle Cap: a Proof-of-Concept Pilot Study.

    Science.gov (United States)

    Hengge, Ulrich R

    2014-12-01

    Cradle cap is a very common condition in infants that presents as greasy, scaly patches on the scalp within the first weeks of life. Although usually disappearing by itself, the condition worries parents because of its appearance. When removing the scales, it is crucial to prevent spot bleedings to avoid infections. The investigational medical device LOYON(®) (Cetiol(®) CC, dimethicone) solution (G. Pohl-Boskamp GmbH & Co. KG, Hohenlockstedt, Germany) has the potential to meet these needs since it removes scales gently. It was, therefore, the aim of this proof-of-concept study to assess the efficacy and safety of topically applied, non-medicated LOYON(®) in facilitating the removal of scaling in infants and children with cradle cap without inducing spot bleedings. This single-center, open, proof-of-concept, pilot study was conducted in 20 male or female infants/children aged 3-36 months with clinically diagnosed cradle cap. The 8-day study period included one to three applications of LOYON(®). Clinical assessment of scaling and secondary parameters was performed at baseline and after treatment. Adverse events were recorded. A questionnaire on subjective efficacy and usability was handed out to the parents. With a maximum of three applications of LOYON(®) applied to 20 subjects, a reduction in scaling intensity from moderate or severe to very mild or mild was achieved in 80% of the subjects. Treatment success, defined as the reduction of the scaling baseline score by at least two points, was achieved in 50% of subjects. Results of this study do not indicate any safety concern. No spot bleedings were observed. LOYON(®) was generally well tolerated and overall treatment was rated as "good" by the parents/legal guardians. This study suggests that LOYON(®) is well tolerated, safe and effective in facilitating the removal of scaling in infants and children with cradle cap. With its gentle approach and rapid effect, LOYON(®) thus represents a good alternative to

  8. 非医学专业女大学生乳房自我检查现状调查及对策%Status investigation on breast self -examination of non -medical female university students and the countermeasure

    Institute of Scientific and Technical Information of China (English)

    周翠云; 邓燕萍; 林佳; 黄燕青; 刘晓莺

    2016-01-01

    Objective To understand the cognition situation of breast self-examination ( BSE) among non-medical specialty female college students and to provide the basis information for non-medical colleges to develop health care curriculum.Methods Self -designed questionnaires were conducted among randomly selected female college students from a college in Fuzhou City.Results 27.4%of non-medical specialty female college students have heard of BSE, 35.1% of them know the purpose of BSE, 29.5% of them know the necessity of BSE, 11.2%of them know the method of BSE, 32.3%of them know the best age of BSE,16.8%of them know the frequency of BSE.Conclusions The current situation of non -medical college students about breast self-examination ( BSE) is not optimistic, Health education should be carried out among non-medical colleges to improve their breast health knowledge and consciousness.%目的 了解非医学专业女大学生乳房自我检查( breastself-examination,BSE)现状,为非医学类高等院校开展相应的卫生保健课程提供一定的参考依据. 方法 抽取福州市某所高等院校非医学专业女大学生,采用自行设计的问卷进行调查. 结果 了解BSE的占27.4%,明确BSE的目的占35.1%,明确BSE的必要性占29.5%,知晓BSE的方法占11.2%,知晓BSE的最佳年龄占32.3%,知晓BSE的频率占16 .8%. 结论 非医学专业女大学生对乳房自我检查的现状不容乐观;非医学类高等院校应积极开展卫生保健教育,提高女大学生对乳房的保健意识.

  9. Investigation and analysis of the demodex infection between medical students and non-medical students%医学专业和非医学专业学生蠕形螨感染情况调查与分析

    Institute of Scientific and Technical Information of China (English)

    孙淼; 朱文; 刘宝; 刘静秋; 吴恩昊; 张文霞

    2016-01-01

    目的::掌握滁州地区学生蠕形螨感染状况并分析感染原因,为蠕形螨感染的预防和治疗提供实验依据。方法:采用自制问卷调查并运用透明胶带粘贴过夜法抽查医学专业学生162人和非医学专业学生186人,利用光学显微镜观察结果。结果:医学专业学生蠕形螨感染率明显低于非医学专业学生(P<0.01),而医学专业学生对蠕形螨知晓率显著高于非医学专业学生(P<0.01)。结论:普及蠕形螨知识、提高蠕形螨知晓率对预防蠕形螨感染和蠕形螨病有重要意义。%Objective:To investigate the situation of demodex infection in students in Chuzhou,and analyze its reasons for providing the experimental evidence in preventing and treating the demodex infection. Methods:One hundred and sixty-two medical students and 186 non-medical students were investigated using the transparent adhesive tape overnight method and self-made questionnaire. The demodex was observed using optical microscopy. Results:The infection rate of demodex in medical students was significantly lower than that in non-medical students(P<0. 01),and the awareness rate of demodex in medical students was significantly higher than that in non-medical students (P<0. 01). Conclusions:Popularizing the demodex knowledge and improving the demodex awareness have great significance in preventing the demodex infection and demodicidosis.

  10. A survey of the non-medical college students' sexual knowledge and attitude%非医学专业大学生性知识、性观念现状调查

    Institute of Scientific and Technical Information of China (English)

    谢锦伟; 高昕; 范婧慧; 高喜璨; 朱俊勇

    2013-01-01

    Objectives:To explore non-medical undergraduates' knowledge and awareness of sex and their demand for sex education,and to provide theoretical reference for implementation of sex education among college students.Methods:Anonymous questionnaires titled "Sex and Health" were given to non-medical undergraduates.Results:Validated questionnaire rate is 99.2% (129/130).40.3% of them know how to project safe period,with a highly significant difference between male students and female ones (P < 0.001).The main accesses to sex knowledge are from domestic and foreign videos and the Internet.There are significant differences (P < 0.05) between male and female students,between urban and rural students in terms of reading medical books and pornography.72.87% think premarital sex depends on individuals.68.99% believe that,for college students,to love is to enrich spiritual life.Conclusion:Non-medical students lack knowledge about sex.Their access to sex knowledge is limited.Their attitude towards sex is too open.It is necessary to conduct sex education among non-medical students.%目的:了解非医学专业大学生性知识来源与知晓度、性观念现状及非医学专业大学生对性教育的需求情况,为有针对性的开展大学生性教育提供理论参考.方法:匿名问卷调查《性与健康》课程的非医学专业大学生.结果:回收有效问卷99.2% (129/130),对性知识的知晓度参差不齐,对如何推算女性安全期的知晓率仅为40.31%,男女生之间有高度显著性差异(P<0.001).获得性知识的途径主要是国内外影视与上网,在医药卫生书籍、色情读物方面,男女生之间、来自城市与农村的学生之间有显著性差异(P<0.05).72.87%的学生认为婚前性行为取决于个人自由,68.99%的学生认为大学生谈恋爱是为了丰富精神生活.结论:非医学专业大学生的性知识相对缺乏,获取性知识的途径相对单一,性观念过于开放,在非医学

  11. Improving the Army Hospital Satisfaction and Reducing the Defects of Non-medical Factors%减少非医疗因素缺陷,提高部队医院满意度

    Institute of Scientific and Technical Information of China (English)

    王国芳

    2013-01-01

    本文从医患沟通、医疗费用、医德医风、医院的安全保障、医院形象、医护人员素质等六方面论述了非医疗因素缺陷其对医院整体满意度的影响,并提出具体整改措施。%This article discuss the factors of affecting the overall hospital satisfaction from some aspect of non-medical reasons,such as the communication between doctors and patients,medical expenses,medical ethics,the hospital security,the image of the hospital,the medical care personnel quality,and puts forward some concrete measures of increasing overall hospital satisfaction.

  12. 非医学需要剖宫产的危险因素研究%The study on risk factors for cesarean section for non-medical needs

    Institute of Scientific and Technical Information of China (English)

    徐桂莲

    2015-01-01

    Objective To understand the risk factors for non-medical needs of cesarean section,and to provide evidence for controling non-medical needs of cesarean section. Methods 1070 cases expectant mothers who were gestational age ≥ 24 weeks were collected as the study.They were divided into the vaginal delivery group (control group) and non-medical needs of cesarean group (experimental group) according to the final delivery metheod.Then case-control study was done to them. Results The Proportion of residents in the town,mental and high-income families of the experimental group ware higher than the control group. The pregnant women of the experimental group were more concerned about the safety, body, smart kid, et al. and they worried about the pain and sexual life after childbirth. The pregnant women of the control were more concerned about the cost, the natural physiological processes and the post-natal recovery. Multivariate analysis showed that:a more perfect ending cesarean section,vaginal birth would affect the sex life, the doctor recommended mode of delivery, vaginal birth were natural child birth and quick recovery, pregnancy intention of cesarean section had a significant impact for pregnant women to choose caesarean. Conclusion The cognitive behavioral deviations can lead to non-medical needs of prignant women select cesarean section. Therefore, we shoule strengthen the mission mode of delivery to the pregnant women, Cognitiving advantages and disadvantages of cesarean is the key of reducing the rate of cesarean and improving the quality of obstetric.%目的:了解非医学需要剖宫产的危险因素,为非医学需要剖宫产的控制提供依据。方法收集1070例孕周≥24周的待产产妇为研究对象,根据最终分娩方式分为阴道分娩组(对照组)与非医学需要剖宫产组(试验组),然后进行病例对照研究等统计学分析。结果试验组中镇居民、脑力劳动者、高收入家庭的比例高于对

  13. Direct Democracy

    DEFF Research Database (Denmark)

    Doerr, Nicole

    2013-01-01

    Direct democracy describes a theory of democracy and a form of collective decision-making in which sovereignty is directly exercised by the people. Democracy is direct if it is characterized by citizens making all decisions together with a maximum of equal participation. Direct democracy can...

  14. Investigation of Non-Medical Students of Food Borne Parasitic Cognition Degree of Yunnan Certain Universities%云南某高校非医药学生食源性寄生虫认知程度调查

    Institute of Scientific and Technical Information of China (English)

    李普娟; 张莉; 陈旭; 刘灿; 杨小娟; 孙济泽

    2015-01-01

    Objective To understand the situation of a university non-medical student about the knowledge of the food-borne parasites and its prevention,control.Methods 2000 non-medical students were selected from three dif erent grand batch by stratified random sampling in May 2013,were asked to complete questionnaires about the knowledge of the food-borne parasites.Results The percentage of cognition about the food-borne parasites was 56.7%,the students had some knowledge of the relationship betweenparasiticdiseaseand life style,behavior,had some knowledge about parasites disease prevention and control.Conclusion We should strengthen the students awareness of the food-borne parasite.%目的了解某高校非医药学专业学生对食源性寄生虫和防治知识相关态度的知晓情况。方法通过分层随机抽样于2013年5月对某高校非医药学专业三个不同年级共2000名学生进行食源性寄生虫知识的问卷调查。结果某高校非医药类专业学生对食源性寄生虫总知晓率为56.74%,对寄生虫与生活方式、行为卫生关系、相关寄生虫预防知识有一定的了解。结论加强对学生的食源性寄生虫相关知识宣传力度。

  15. 医学目的与非医学目的基因增强产生的伦理问题辨析∗%Ethical Analysis of Medical Purpose and Non-medical Purpose Gene Enhancement

    Institute of Scientific and Technical Information of China (English)

    徐莎; 苏振兴

    2016-01-01

    作为一种新兴技术,无论医学目的基因增强还是非医学目的基因增强应用中所产生的诸多伦理问题都是不可避免的,片面的赞同或反对医学目的基因增强或非医学目的基因增强的研究和应用都是不切实际的。应该在规范基因增强技术伦理原则的基础上,构建以伦理、社会、法律相适应的基因增强技术的研究、发展及应用的管理措施,进而达到趋利避害的目的,使基因增强技术合理地利用并使之真正造福于人类社会。%As a kind of new technology, ethical issues are inevitable in medical and non-medical gene en-hancement application. It is unrealistic to unilaterally support or object to the research and application of medical and non -medical gene enhancement. Based on standardizing the ethical principle of gene enhancement tech-niques, we should build management measures of the research, development and application that adapted to ethi-cal, social and legal standards, so that we can draw on the advantages and avoid the disadvantages, and use gene enhancement reasonably and bring benefits to mankind and society.

  16. Directed homology

    DEFF Research Database (Denmark)

    Fahrenberg, Uli

    2004-01-01

    We introduce a new notion of directed homology for semicubical sets. We show that it respects directed homotopy and is functorial, and that it appears to enjoy some good algebraic properties. Our work has applications to higher-dimensional automata.......We introduce a new notion of directed homology for semicubical sets. We show that it respects directed homotopy and is functorial, and that it appears to enjoy some good algebraic properties. Our work has applications to higher-dimensional automata....

  17. 医学专业和非医学专业大学生艾滋病知信行比较研究%Comparative Study of AIDS KAP between Medical Students and Non-medical Students

    Institute of Scientific and Technical Information of China (English)

    连肖; 肖模银

    2012-01-01

    Objective:To Learn the acknowledgement,highly-risky behaviors and attitudes towards AIDS among medical students and non-rnedical students in the comprehensive university, in order to find out the defects in health-care education of AIDS and to provide scientific suggestions for drawing up all-sides and systemic measures for health education.Methods: A total of 299 medical students and 1412 non-medical students were selected by using the stratified cluster sampling method in a comprehensive university and surveyed by self-designed questionnaire.Results: The difference of AIDS awareness and attitude between medical students and non-medical students was significant-There are some students who used to have dangerous behaviors of AIDS in both medical students and non-medical students^ and the difference of behaviors between two groups is not significant. The students mainly get information of AIDS from media, like telecast and internet. Conclusion: Medical students' score is better than that of non-medical students in AIDS-related knowledge and attitudes toward AIDS, both of the two majors have a high awareness of the three major routes of AIDS transmission and basic knowledge of AIDS. Based on different characteristics and demands of different departments in universities, university authorities should draw up a systematic and particular health education measures on AIDS, meanwhile, universities should make full use of the professional status of medical students, and let them play a role of YPE to other non-medical students. Arouse the whole society to give health education of AIDS to students.%目的:了解综合性大学医学专业和非医学专业学生艾滋病相关的知识、行为以及态度,为制定全面系统的大学生艾滋病健康教育提供科学建议.方法:自行设计调查问卷,采用多级分层整群抽样方法选取医学生229名、非医学生1412名进-问卷调查.结果:医学生与非医学生对艾滋病基本知识和传播途径

  18. 哮喘患者非药物治疗依从性与生存质量的相关性研究%Correlation of Compliance to Non-medical Therapy with Quality of Life in Asthmatic Patients

    Institute of Scientific and Technical Information of China (English)

    陆悦; 崔磊; 张静

    2012-01-01

    Objective To investigate the correlation between compliance to non - medical therapy and quality of life in adult patients with asthma. Methods A self - designed questionnaire of compliance to non - medical therapy ( compliance questionnaire ) and Asthma Quality of Life Questionnaire ( AQLQ ) were used here to investigate 129 asthmatic outpatients from 2 third - graded hospitals in Beijing. Results The total score of compliance questionnaire in the adult patients with asthma was ( 3. 7 ± 0. 6 ), and the total score of AQLQ was ( 4. 1 ± 0. 4 ). The average scores of inducement avoidance and self - monitoring domain of compliance questionnaire were positively correlated with the average scores of the total and each domain of AQLQ ( except the e-motional function domain ) ( r =0. 175 ~0. 429, P < 0. 05 ). The average score of physical activity domain in compliance questionnaire was positively related with that of symptoms domain in AQLQ ( r = 0. 255 , P < 0. 01 ). The score of health responsibility domain in compliance questionnaire was positively correlated with that of environmental stimuli domain in AQLQ ( r = 0. 234 , P < 0. 01 ) . Conclusion The patients should be encouraged to avoid inducing factors and keep self - monitoring, do physical exercise purposely, and increase health responsibility. It is helpful for improving the quality of life to pay more attention to the compliance to non - medical therapy for asthmatic patients.%目的 探讨成人哮喘患者非药物治疗依从性与其生存质量间的相互关系.方法 采用自行设计的哮喘非药物治疗依从性问卷(依从性问卷)和成人哮喘生存质量量表(AQLQ)对北京市某两家三甲医院门诊就诊的129例哮喘患者进行调查.结果 成人哮喘患者依从性问卷总均分为(3.7±0.6)分,AQLQ总均分为(4.1±0.4)分,依从性问卷的避免诱因和自我监测维度均分与AQLQ的总均分和各维度均分(除心理情绪维度)呈正相关(r值为0.175~0.429,P

  19. Direct Democracy

    DEFF Research Database (Denmark)

    Beramendi, Virginia; Ellis, Andrew; Kaufman, Bruno

    While many books on direct democracy have a regional or national approach, or simply focus on one of the many mechanisms associated with direct democracy, this Handbook delves into a global comparison of direct democracy mechanisms, including referendums, citizens' initiatives, agenda initiatives...... included as a chapter in the Handbook are possible measures for best practices of implementation, designed for those who wish to tailor direct democracy instruments to their specific needs. In order to further complement the best practices, a variety of global case studies detail the practical uses...... of direct democracy mechanisms in specific contexts. These country case studies allow for in depth discussion of particular issues, including signature collection and voter participation, campaign financing, media coverage, national variations in the usage of direct democracy procedures and national lessons...

  20. Direct Democracy

    DEFF Research Database (Denmark)

    Beramendi, Virginia; Ellis, Andrew; Kaufman, Bruno

    While many books on direct democracy have a regional or national approach, or simply focus on one of the many mechanisms associated with direct democracy, this Handbook delves into a global comparison of direct democracy mechanisms, including referendums, citizens' initiatives, agenda initiatives...... valuable information regarding the binding or non-binding nature of referendums, as well as issues that can be brought forth to a referendum....

  1. 非医学信息学专业医学信息学教育课程的设置%Construction of medical informatics curriculum based on IMIA recommendations for non-medical informatics students

    Institute of Scientific and Technical Information of China (English)

    曹洪欣; 汤琳; 单甜甜

    2012-01-01

    According to the recommendations of the International Medical lnformatics Association(IMIA)on education in biomedical and health informatics(first revision)published by IMIA in 2010 and combining the actuality of the basic clinical information skills and medical informatics education of Chinese medical students,the related contents of medical informatics have been integrated into the teaching course based on current medical information retrieval curriculum and medical informatics curriculum for non-medical informatics students of medical colleges and universities was constructed,so that they can meet the requirements of the basic information skills under information-based medical and healthy practice.%以国际医学信息学会(International Medical Informatics Association,IMIA)2010年修订的《关于开展生物医学与健康信息学教育的建议》为依据,结合我国目前医学生基本临床信息技能及医学信息学教育现状,以医学文献检索为课程基础,构建适合高等医学院校非医学信息学专业教育的医学信息学课程,使医学生毕业后能够适应信息化条件下医疗卫生实践对基本信息技能的要求.

  2. Gamma hydroxybutyrate (GHB), gamma butyrolactone (GBL) and 1,4-butanediol (1,4-BD; BDO): A literature review with a focus on UK fatalities related to non-medical use.

    Science.gov (United States)

    Corkery, John M; Loi, Barbara; Claridge, Hugh; Goodair, Christine; Corazza, Ornella; Elliott, Simon; Schifano, Fabrizio

    2015-06-01

    Misuse of gamma hydroxybutrate (GHB) and gamma butyrolactone (GBL) has increased greatly since the early 1990s, being implicated in a rising number of deaths. This paper reviews knowledge on GHB and derivatives, and explores the largest series of deaths associated with their non-medical use. Descriptive analyses of cases associated with GHB/GBL and 1,4-butanediol (1,4-BD) use extracted from the UK's National Programme on Substance Abuse Deaths database. From 1995 to September 2013, 159 GHB/GBL-associated fatalities were reported. Typical victims: White (92%); young (mean age 32 years); male (82%); with a drug misuse history (70%). Most deaths (79%) were accidental or related to drug use, the remainder (potential) suicides. GHB/GBL alone was implicated in 37%; alcohol 14%; other drugs 28%; other drugs and alcohol 15%. Its endogenous nature and rapid elimination limit toxicological detection. Post-mortem blood levels: mean 482 (range 0-6500; SD 758)mg/L. Results suggest significant caution is needed when ingesting GHB/GBL, particularly with alcohol, benzodiazepines, opiates, stimulants, and ketamine. More awareness is needed about risks associated with consumption.

  3. Directing Creativity

    DEFF Research Database (Denmark)

    Darsø, Lotte; Ibbotson, Piers

    2008-01-01

    In this article we argue that leaders facing complex challenges can learn from the arts, specifically that leaders can learn by examining how theatre directors direct creativity through creative constraints. We suggest that perceiving creativity as a boundary phenomenon is helpful for directing it....... Like leaders, who are caught in paradoxical situations where they have to manage production and logistics simultaneously with making space for creativity and innovation, theatre directors need to find the delicate balance between on one hand renewal of perceptions, acting and interaction...... and on the other hand getting ready for the opening night. We conclude that the art of directing creativity is linked to developing competencies of conscious presence, attention and vigilance, whereas the craft of directing creativity concerns communication, framing and choice....

  4. Future directions.

    Science.gov (United States)

    Raffa, Robert B; Tallarida, Ronald J

    2010-01-01

    The chapters of this book summarize much of what has been done and reported regarding cancer chemotherapy-related cognitive impairment. In this chapter, we point out some future directions for investigation.

  5. 关于开展急救技术普及教育的方法研究与探讨%First aid skills education among non-medical students: experience from practice in Jiangsu University

    Institute of Scientific and Technical Information of China (English)

    邹圣强; 眭建; 李萍萍; 陈文娟; 潘鑫; 吴敏

    2011-01-01

    Since 2004 an optional basic first aid course has been held among non-medical students in Jiangsu University in corporation with Zhenjiang Medical Emergency Center. The 24-hour curriculum includesmanual cardiopulmonary resuscitation (CPR), Heimlich maneuver, 5 basic techniques of elementary first aid (ventilation, hemostasia, wound dressing, fixation, and transportation of the wounded), on-the-spot emergency treatment of falling, traffic accidents, drowning, electric shock, suicide, etc, escape techniques and self-help and mutual aid during disasters, such as fire, toxicant gas poisoning, explosion, epidemic of infectious diseases,etc. Different forms of education, such as lecture with modernized acousto-optic technique, practical operation,academic forum, competition of theory and practice, and field exercise were integrated. In 2007 the First Aid Association of Jiangsu University was established. After 7-years' education the knowledge rate of first aid among the non-medical students was raised from 8.29% to 100%, and the qualification rate of CPR was 84.45%. The practice showed that first aid education is necessary and the current forms of education are effective.%从2004年开始江苏大学与镇江市急救医疗中心合作,在非医学生中举办讲授初级急救基础知识和基本急救技能的24学时的选修课.课程包括徒手心肺复苏(CPR),Heimlich氏手法,初级急救五项基本技术(通气、止血、包扎、固定和搬运急救技术),摔伤、交通事故伤、溺水、电击伤、自杀等常见意外伤害和常见急症的现场急救方法,以及火灾、有毒气体中毒、爆炸和常见传染病等突发事件的现场避险逃生技能和自救互救知识.教学形式多样,结合了现代化的声像技术,实际操作,学术论坛,理论和实践竞赛,野外演练等.7年后的调查表明,非医学生中急救知识合格率从8.29%升到100%,CPR合格率84.45%.实践证明急救教育非常必要,目前的教学形式是有效的.

  6. 大学生急救能力相关调查及比较研究%First aid ability related investigation and comparative study of medical students and non medical students

    Institute of Scientific and Technical Information of China (English)

    王超; 黄丹; 武继文

    2016-01-01

    ①目的全面了解大学生基础急救技能的掌握情况与培训需求。②方法采取方便抽样的调查方式,对南京城区医学与非医学专业大学生急救相关情况进行初步调研。③结果889.%的大学生知道急救电话是120,自评“会操作”各单项基础急救技能的概率在10%左右;947.%以上的大学生认为有必要掌握基础急救技能;网络电视和学校培训是目前大学生获得急救知识的主要途径;认为培训最佳场所是学校的大学生相对较多,培训最佳方式选择利用专门的人体模型模拟练习的占大多数;医学生急救技能明显高于非医学生。④结论大学生对急救技能需求较强,对大学生的急救技能培训工作十分迫切;培训地点可选择在校园内,讲座结合模拟练习应是最佳培训方式。医学院校可以在大学城急救培训中发挥积极作用。%[ABBSTRACT] Objective To fully understand the students'basic first aid skills and training needs . Methods Taking the convenience sample survey method ,the relevant circumstances of the first aid a‐bility of the medical and non medical college students in Nanjing city were investigated preliminarily . Results Only 88 9.% of the students know the emergency telephone number is 120 .The ratio of self -assessment "mastering the operation"of each individual basic first aid skill is around 10% .More than 94 7.% college students think it is necessary to grasp the basic first aid skills .Network and television to‐gether with school training are the main ways to obtain first aid knowledge for college students .More college students believe that the best place for training is campus and the best way is the simulative ex‐ercising on specialized human model .Medical students'first aid skills were significantly higher than those of non medical students .Conclusion Students have strong demand for first aid skills ,and first aid Publicity and training

  7. Directed Replacement

    CERN Document Server

    Karttunen, L

    1996-01-01

    This paper introduces to the finite-state calculus a family of directed replace operators. In contrast to the simple replace expression, UPPER -> LOWER, defined in Karttunen (ACL-95), the new directed version, UPPER @-> LOWER, yields an unambiguous transducer if the lower language consists of a single string. It transduces the input string from left to right, making only the longest possible replacement at each point. A new type of replacement expression, UPPER @-> PREFIX ... SUFFIX, yields a transducer that inserts text around strings that are instances of UPPER. The symbol ... denotes the matching part of the input which itself remains unchanged. PREFIX and SUFFIX are regular expressions describing the insertions. Expressions of the type UPPER @-> PREFIX ... SUFFIX may be used to compose a deterministic parser for a ``local grammar'' in the sense of Gross (1989). Other useful applications of directed replacement include tokenization and filtering of text streams.

  8. Directing Creativity

    DEFF Research Database (Denmark)

    Darsø, Lotte; Ibbotson, Piers

    2008-01-01

    In this article we argue that leaders facing complex challenges can learn from the arts, specifically that leaders can learn by examining how theatre directors direct creativity through creative constraints. We suggest that perceiving creativity as a boundary phenomenon is helpful for directing it....... Like leaders, who are caught in paradoxical situations where they have to manage production and logistics simultaneously with making space for creativity and innovation, theatre directors need to find the delicate balance between on one hand renewal of perceptions, acting and interaction...

  9. Direct marketing

    Directory of Open Access Journals (Sweden)

    Čičić Muris

    2002-01-01

    Full Text Available Direct Marketing (DM is usually treated as unworthy activity, with actions at the edge of legality and activities minded cheating. Despite obvious problems regarding ethics and privacy threat, DM with its size, importance and role in a concept of integrated marketing communication deserves respect and sufficient analysis and review

  10. Direct ELISA.

    Science.gov (United States)

    Lin, Alice V

    2015-01-01

    First described by Engvall and Perlmann, the enzyme-linked immunosorbent assay (ELISA) is a rapid and sensitive method for detection and quantitation of an antigen using an enzyme-labeled antibody. Besides routine laboratory usage, ELISA has been utilized in medical field and food industry as diagnostic and quality control tools. Traditionally performed in 96-well or 384-well polystyrene plates, the technology has expanded to other platforms with increase in automation. Depending on the antigen epitope and availability of specific antibody, there are variations in ELISA setup. The four basic formats are direct, indirect, sandwich, and competitive ELISAs. Direct ELISA is the simplest format requiring an antigen and an enzyme-conjugated antibody specific to the antigen. This chapter describes the individual steps for detection of a plate-bound antigen using a horseradish peroxidase (HRP)-conjugated antibody and luminol-based enhanced chemiluminescence (ECL) substrate. The methodological approach to optimize the assay by chessboard titration is also provided.

  11. Directing Lives

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    YANG Yang is he director of China Television PlayCenter.Before the arrival of the series Holding Hands,she filmed television plays reflecting women and marriage.Examples of her work include Niu Yuqin and Her Trees and theMidnight Trolley.The artistry and sympathy towards women inthese programmes make it obvious that they were directed by awoman.Holding Hands especially cements this connection.

  12. 未服药的强迫障碍患者脑灰质体积异常的MRI研究%Abnormal brain gray matter volume in non-medicated patients with obsessive-compulsive disorder: A MRI study

    Institute of Scientific and Technical Information of China (English)

    李平; 李占江; 罗佳; 郭志华; 韩海英; 熊红芳; 姚淑敏

    2012-01-01

    目的:应用脑磁共振成像(MRI)基于体素的形态测量学(VBM)比较未服药的强迫障碍患者脑灰质体积与正常人群间的差异,并探讨强迫障碍患者脑灰质体积的改变与临床现象之间的相关性.方法:纳入符合美国精神障碍诊断与统计手册第4版(DSM-Ⅳ)诊断标准的20例未服药的强迫障碍门诊患者,以及20名性别、年龄和受教育程度相匹配的健康对照.所有被试均接受头部磁共振扫描.采用VBM的分析方法,比较强迫障碍患者与健康对照之间脑灰质体积的差异.采用耶鲁-布郎强迫量表(Y-BOCS)、汉密顿抑郁量表(HAMD)、汉密顿焦虑量表(HAMA)评估临床症状.在控制焦虑、抑郁症状的前提下,分析强迫障碍患者异常的脑灰质体积与临床现象之间的关系.结果:与对照组相比,强迫障碍组的眶额回、颞上回、颞下回、小脑、楔前叶、辅助运动区及中央后回的灰质体积减少(P<0.05,AlphaSim校正);眶额回灰质体积的减少与Y-BOCS量表总分呈负相关(r=-0.49,P<0.05).结论:本研究结果提示眶额-纹状体-丘脑环路中的眶额回在强迫障碍的发生中起重要的作用,其他脑区如颞叶和小脑灰质体积减少,可能也参与了强迫障碍的发生.%Objective: To explore the gray matter volume in non-medicated patients with obsessive-compulsive disorder (OCD), and to investigate the correlations between abnormal gray matter volume and clinical symptoms. Methods: Twenty non-medicated patients with OCD and twenty gender-, age-, education-matched healthy subjects participated in the magnetic resonance imaging (MRI) scan. Voxel-based morphometry (VBM) was used to analyze the MRI data. The Yale-Brown Obsessive-Compulsive Scale (YBOCS), Hamilton Depression Rating Scale (HAMD) and Hamilton Anxiety Rating Scale (HAMA) were used to assess clinical symptoms. Total HAMA and HAMD score were taken as covariates to control for comorbid symptoms, and then the partial

  13. 非医疗因素对长期腹膜透析患者生存质量的影响%The effect of non-medical factors on the quality of life in maintenance peritoneal dialysis patients

    Institute of Scientific and Technical Information of China (English)

    田娜; 陈孟华

    2009-01-01

    Objective To evaluate the quality of life (QOL) in continuous ambulatory peritoneal dialysis (CAPD) patients and analyze the non-medical factors influencing QOL in order to explore the possible way to improve QOL in peritoneal dialysis (PD) patients.Methods Seventy-nine chronic renal failure patients treated with PD included in the present study.Investigated their age,sex,working status,education,medical burden and family support.Patients' QOL was evaluated by international questionnaire-KDQOL/SF-36.Patients' anxiety/depmssion status was evaluated by Hamilton depression questionnaire.Results (1)The SF-36 with its eight scales of CAPD patients were markedly lower than ordinary people (P<0.05 or<0.01).(2) Comparing with those on work,the patients without work got lower SF-36 scores[(45.78±16.93) seores vs (32.65±12.26) scores,P<0.05].Comparing with those who had medical care,the patients without medical care got much lower SF-36 scores [(49.62±13.20) scores vs (33.85±6.24) scores,P<0.05].Patients with higher income had better QOL.(3) Patients cared by their children and companion had the higheat SF-36 [(68.33±14.73) scores],while those cared by nursemaid or themselves had the lowest [(27.98±15.77) scores].(4) Among the 79 patients,43 patients (54.4%) were anxiety and 12 patients (15.2%) were depression.QOL was negatively correlated with anxiety index and depression index.Conclusion The QOL of CAPD patients are remarkably low,which is deeply influenced by many non-medical factors such as working status,medical burden,family support and emotional status.%目的 研究可能影响长期腹膜透析患者生存质量的非医疗因素,旨在为临床工作中如何提高患者的生存质量提供依据.方法 采用横断面研究方法调查79例慢性肾衰竭进行持续非卧床腹膜透析(CAPD)患者.记录患者的年龄、性别、工作状况、文化程度、医疗负担及家庭支持等情况.采用国际通用的KDQOL-SFTM1.2中的短表SF-36

  14. Future direction of direct writing

    Science.gov (United States)

    Kim, Nam-Soo; Han, Kenneth N.

    2010-11-01

    Direct write technology using special inks consisting of finely dispersed metal nanoparticles in liquid is receiving an undivided attention in recent years for its wide range of applicability in modern electronic industry. The application of this technology covers radio frequency identification-tag (RFID-tag), flexible-electronics, organic light emitting diodes (OLED) display, e-paper, antenna, bumpers used in flip-chip, underfilling, frit, miniresistance applications and biological uses, artificial dental applications and many more. In this paper, the authors have reviewed various direct write technologies on the market and discussed their advantages and shortfalls. Emphasis has given on microdispensing deposition write (MDDW), maskless mesoscale materials deposition (M3D), and ink-jet technologies. All of these technologies allow printing various patterns without employing a mask or a resist with an enhanced speed with the aid of computer. MDDW and M3D are capable of drawing patterns in three-dimension and MDDW, in particular, is capable of writing nanoinks with high viscosity. However, it is still far away for direct write to be fully implemented in the commercial arena. One of the hurdles to overcome is in manufacturing conductive inks which are chemically and physically stable, capable of drawing patterns with acceptable conductivity, and also capable of drawing patterns with acceptable adhesiveness with the substrates. The authors have briefly discussed problems involved in manufacturing nanometal inks to be used in various writing devices. There are numerous factors to be considered in manufacturing such inks. They are reducing agents, concentrations, oxidation, compact ability allowing good conductivity, and stability in suspension.

  15. Advance care directives

    Science.gov (United States)

    ... advance directive; Do-not-resuscitate - advance directive; Durable power of attorney - advance care directive; POA - advance care directive; Health care agent - advance care directive; Health care proxy - ...

  16. Numerical simulations of blast-impact problems using the direct simulation Monte Carlo method

    Science.gov (United States)

    Sharma, Anupam

    There is an increasing need to design protective structures that can withstand or mitigate the impulsive loading due to the impact of a blast or a shock wave. A preliminary step in designing such structures is the prediction of the pressure loading on the structure. This is called the "load definition." This thesis is focused on a numerical approach to predict the load definition on arbitrary geometries for a given strength of the incident blast/shock wave. A particle approach, namely the Direct Simulation Monte Carlo (DSMC) method, is used as the numerical model. A three-dimensional, time-accurate DSMC flow solver is developed as a part of this study. Embedded surfaces, modeled as triangulations, are used to represent arbitrary-shaped structures. Several techniques to improve the computational efficiency of the algorithm of particle-structure interaction are presented. The code is designed using the Object Oriented Programming (OOP) paradigm. Domain decomposition with message passing is used to solve large problems in parallel. The solver is extensively validated against analytical results and against experiments. Two kinds of geometries, a box and an I-shaped beam are investigated for blast impact. These simulations are performed in both two- and three-dimensions. A major portion of the thesis is dedicated to studying the uncoupled fluid dynamics problem where the structure is assumed to remain stationary and intact during the simulation. A coupled, fluid-structure dynamics problem is solved in one spatial dimension using a simple, spring-mass-damper system to model the dynamics of the structure. A parametric study, by varying the mass, spring constant, and the damping coefficient, to study their effect on the loading and the displacement of the structure is also performed. Finally, the parallel performance of the solver is reported for three sample-size problems on two Beowulf clusters.

  17. 非药物治疗缓解新生儿疼痛效果比较%Comparing the effects in non-medical intervention to alleviate the pain of the neonatal infants

    Institute of Scientific and Technical Information of China (English)

    陈建芳; 徐亮

    2011-01-01

    Objective To investigate different methods in alleviation of pain in neonatal infants. Methods One hundred and sixty neonatal infants were randomly divided into four groups, 40 infants for each group, including control group, transmitting tactile sensation group ( TTS) , glucose group ( GS) and non-nutritive sucking group ( NNS) . Heart rate, respiratory rate, oxygen saturation and crying duration among the four groups at 20 s, 1 min, 2 min, 3 min before and after heel stick were compared. Results Heart rate and respiratory rate of neonatal infants at 20 seconds after heel stick were significantly higher in all groups (P 0. 05 ) . The crying durations in intervention groups was significantly shorter than that of control group (P < 0.01 ) . Crying duration in TTS group was significantly shorter than in all the other intervention groups ( P < 0. 05 ) . Conclusions Neonatal infants have sensitive response to acute pain stimulation. Transmitting tactile sensation, glucose and non-nutritive sucking have significant analgesic effects on neonatal infants. The non-medical intervention methods, should be used in the clinical nursing care to alleviate the pain of the neonatal infants.%目的 探讨不同干预方法缓解新生儿疼痛的效果.方法 将160例住院新生儿随机分为对照组(未干预组)、拥抱抚触(TTS)组、吸吮8%葡萄糖水(GS)组和非营养性吸吮(NNS)组各40例,在采足跟血疼痛刺激前、刺激后20 s、1min、2 min、3 min分别记录心率、呼吸频率、经皮氧饱和度和哭声持续时间.结果 穿刺后20 s各组心率、穿刺后1 min各组呼吸均较穿刺前增快,差异有统计学意义(P<0.01);1 min时TTS组心率恢复至穿刺前水平;2 min时TTS组呼吸频率,GS组和NNS组心率和呼吸频率恢复至穿刺前水平;3 min时对照组恢复至穿刺前水平.各组经皮血氧饱和度穿刺前后差异无统计学意义(P>0.05).穿刺后哭声持续时间TTS组、GS组和NNS组均短于对照

  18. 医学与非医学专业在校大学生对保健品认知及态度的比较%Comparison of cognition and attitude to health care products between medical and non-medical college students

    Institute of Scientific and Technical Information of China (English)

    李茜; 顾燕华; 朱静芬; 孙桂香

    2012-01-01

    目的 了解医学与非医学专业在校大学生对保健品的认知及态度.方法 对3所大学的在校大学生随机抽样进行自填问卷调查.结果 有56%的医学生和63%的非医学生自认为了解保健品的相关知识,但保健品认证标识的知晓率很低(医学生17.7%,非医学生30.2%,P<0.01);对保健品功效的认同率方面,除减肥功效外,医学生均高于非医学生(P<0.05).对保健品的态度:医学生不想尝试新的保健产品的比例(60.1%)高于非医学生(43.9%,P<0.05);医学生认为保健品宣传可信的比例(6.6%)低于非医学生(26.1%,P<0.05);在选择保健品时,医学生看重安全性(28.1%),而非医学生更看重保健功能(24.6%,P<0.05).结论 大学生对于保健品认证标识的知晓率低.医学生对保健品功效的认可率高于非医学生,对保健品的态度也比非医学生更谨慎,不愿贸然尝试新保健品,尤其注重保健品的安全性.%0 b jective To investigate cognition and attitude to health care products amongmedical and non- med-I-cal college students M ethods The students were sanpled with randan samp ling method from three colleges The sup vey was conducted with a self- adm inistered questionnaire R esults 56% ofmedical students and63% of non- med-o cal students thought they had knowledge on health care products But there was low awareness of certification bgo on health care products( 17.7% ofmedical students, non- medical students30. 2% , P <0. 01). The effectiveness rates of health care products of the medical students, except obesity, were higher than those of non- medical students Attitude to health care product, medical students (60. 1% ) who did not try new health products were more than non- medical students(43. 9% , P <0.05). Themedical studentswere less than non- medical students in credibility ofhealth care advocacy (6. 6% vs 26.1% , P <0.05). Themedical students were different from the non- medical students on the choice of health products

  19. Discussion on Non-Medical Bottleneck Factors Affecting City Grade Hospital to Carry Out Peritoneal Dialysis%市级医院开展腹膜透析的“非医疗瓶颈因素”探讨

    Institute of Scientific and Technical Information of China (English)

    万启军; 何永成; 许慧丽; 董旭; 宋海英

    2013-01-01

    Objective To discuss the non-medical bottleneck factors that affect the city grade hospitals to carry out the peritoneal dialysis(PD). Methods Retrospective analyze the clinical data of 160 cases of end-stage renal disease(ESRD) patients on continuous ambulatory peritoneal dialysis(CAPD) treatment from July, 1996 to December,2011 in our hospital,explore the influence of peritoneal dialysis center' s scale size,cost of dialysate,understanding of medical personnel and ESRD patients about peritoneal dialysis on the peritoneal dialysis in our hospital. Compare the difference of the main complications of CAPD between cumulative numbers of patients less than and more than 50; drop-out rate, time on treatment (TOT) ,1 year catheter intact rate and so on. Results The peritoneal dialysis was suggested only by 45. 6% of medical personnel in terms of cost-effect ratio,and by 51. 8% in terms of quality of life. Before the dialysate is charged as a drug,66. 8% of renal physicians suggested patients to choose hemodialysis,but it changed to 43.3% after dialysate is charged as a supply,there is a significant difference(P <0.05). When the cumulative numbers of patients was less than 50, the rates of drop-out rate,death rate, vessel drifting rate, rate of dialysate leaks,tunnel infection rate and PD associated peritonitis were all higher,but the TOT,1 year survival rate and 1 year vessel intact rate were lower,as compare with those when the cumulative numbers of patients was more than 50,and the difference was significance(P <0.05). Conclusion The misunderstanding of renal medicals and the ESRD patients, the way of medical payment and the size of the PD center together limited the speed of the development of PD center.%目的 探讨在市级医院开展腹透的“非医疗瓶颈因素”.方法 分析1996年7月-2011年12月间肾内科160例持续非卧床腹膜透析(CAPD)患者的临床资料,探讨腹透中心规模、腹透液计费方式、医患对腹透的认识等因

  20. 医学院校非医学专业本科生专业承诺及其对自尊水平的影响%Professional commitment and its effect on self-esteem of non-medical professional undergradu-ates in medical colleges

    Institute of Scientific and Technical Information of China (English)

    张东军; 王丽娜; 王玉锋; 杨世昌

    2014-01-01

    Objective To study the status of professional commitment and its effect on self-esteem of non-medical undergraduates in medical colleges. Methods Totally 410 non-medical under-graduates and 403 medical undergraduate were investigated by professional commitment of undergrad-uate scales and self-esteem questionnaire of undergraduates. T test,chi-square test,ANOVA,corre-lation analysis and multiple regression analysis were employed to do statical analysis,with P<0.05 be-ing statistical differences. Results Non-medical undergraduates’scores of professional commitment (85.11 ±11.60)and self-esteem (2.57 ±0.37)were lower than those (93.82 ±11.43)and (2.62 ± 0.35) of medical undergraduates. There were statistical differences in non-medical undergraduates’ professional commitment concerning the variables of professional consistency (t=5.657,P=0.000)and grades (F=8.528,P=0.000). Professional commitment of non-medical undergraduates was positively correlated with self-esteem. There was linear regression relationship between the variables of emotion-al commitment (P=0.005),normative commitment (P=0.006)and self-esteem. Conclusions Non-medical undergraduates' professional commitment and self-esteem levels are lower than those of medical undergraduates. The professional commitment could produce obvious effects on self-esteem.%目的:探讨医学院校非医学专业本科生的专业承诺现状及其对自尊水平的影响。方法采用大学生专业承诺量表、大学生自尊评定问卷对分层随机整群抽取的410名非医学专业及403名医学专业本科生进行问卷调查。对统计数据进行t检验、χ2检验、方差分析、相关分析与多元回归分析。结果非医学专业本科生专业承诺、自尊水平得分均低于医学专业[(85.11±11.60)分vs.(93.82±11.43)分,(2.57±0.37)分vs.(2.62±0.35)分];非医学专业本科生的专业承诺水平在所学专业与报考专业是否一致(t=5.657,P=0.000

  1. OP09O-OP404-9 Wide Field Camera 3 CCD Quantum Efficiency Hysteresis

    Science.gov (United States)

    Collins, Nick

    2009-01-01

    The HST/Wide Field Camera (WFC) 3 UV/visible channel CCD detectors have exhibited an unanticipated quantum efficiency hysteresis (QEH) behavior. At the nominal operating temperature of -83C, the QEH feature contrast was typically 0.1-0.2% or less. The behavior was replicated using flight spare detectors. A visible light flat-field (540nm) with a several times full-well signal level can pin the detectors at both optical (600nm) and near-UV (230nm) wavelengths, suppressing the QEH behavior. We are characterizing the timescale for the detectors to become unpinned and developing a protocol for flashing the WFC3 CCDs with the instrument's internal calibration system in flight. The HST/Wide Field Camera 3 UV/visible channel CCD detectors have exhibited an unanticipated quantum efficiency hysteresis (QEH) behavior. The first observed manifestation of QEH was the presence in a small percentage of flat-field images of a bowtie-shaped contrast that spanned the width of each chip. At the nominal operating temperature of -83C, the contrast observed for this feature was typically 0.1-0.2% or less, though at warmer temperatures contrasts up to 5% (at -50C) have been observed. The bowtie morphology was replicated using flight spare detectors in tests at the GSFC Detector Characterization Laboratory by power cycling the detector while cold. Continued investigation revealed that a clearly-related global QE suppression at the approximately 5% level can be produced by cooling the detector in the dark; subsequent flat-field exposures at a constant illumination show asymptotically increasing response. This QE "pinning" can be achieved with a single high signal flat-field or a series of lower signal flats; a visible light (500-580nm) flat-field with a signal level of several hundred thousand electrons per pixel is sufficient for QE pinning at both optical (600nm) and near-UV (230nm) wavelengths. We are characterizing the timescale for the detectors to become unpinned and developing a protocol for flashing the WFC3 CCDs with the instrument's internal calibration system in flight. A preliminary estimate of the decay timescale for one detector is that a drop of 0.1-0.2% occurs over a ten day period, indicating that relatively infrequent cal lamp exposures can mitigate the behavior to extremely low levels.

  2. 浅谈R语言中OOP编程方法%OOP Programming in the R Language

    Institute of Scientific and Technical Information of China (English)

    白阳椿; 胡荣兴; 邓永超

    2011-01-01

    R is a kind of statistical software widely used as a statistical areas,it has many advantages,such as open source,free,flexible,the programming language is power, but it rarely use object-oriented programming.The paper is a research on R about object-oriented programming in order to let the reader have a better understanding of R software.%R作为统计领域广泛使用的一种统计软件,具有开源、免费、灵活的诸多优点,编程语言强大,但用到面向对象的缔程方法却不多。本文通过对R中面向对象编程的研究,使读者进一步的了解R软件。

  3. The abstracted and integrated Green functions and OOP of BEM in soil dynamics

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    It has been generally recognized that Green function integrated with Boundary Element Method (BEM) has advantages in dimensional reduction, high accuracy and satisfaction of the radiation condition at infinity, etc. Recently, the computational technique has rapidly developed and the orient-object programming has been widely applied, whereas the attribute ofion and the integration of Green function employed in BEM have not been discovered yet. In this work the abstrac- tion and integration of Green function are carried out for soil dynamics problems, and the procedure of the object-oriented calculation method is presented. Based on the Green function developed for the two-phase saturated medium, the re- sponse of the wave field to tunnel subjected to dynamic loading is calculated, and the transient solution as well as the time history of response is obtained.

  4. Opioid overuse pain syndrome (OOPS): the story of opioids, prometheus unbound.

    Science.gov (United States)

    Mehendale, Anand W; Goldman, Mark P; Mehendale, Rachel P

    2013-01-01

    Throughout history, opioids have effectively alleviated pain but not without the risk of addiction and death. Seductive and dangerous, full of promise and destruction, opioids are both revered and feared by Western culture. Their exponential use in "developed countries" is now an enormous public health problem and requires us to harness their properties with scientific rigor and adequate safeguards. The use of opioids for the treatment of chronic nonterminal pain (CNTP) has been a relatively new phenomenon which has coincided with the proclamation by the Joint Commission on Accreditation of Health Care Organization in 2000 that pain assessment be the "fifth vital sign," notwithstanding the fact that pain is a symptom and not a sign.(1) Nonetheless, this resulted in a culture of a marked increase in use of opioids for acute and chronic pain management. Consequently, there are many unintended outcomes which include opioid-induced hyperalgesia increased diversion, addiction, and death. Understandably, this has resulted in many regulatory responses from such agencies such as the Drug Enforcement Administration (DEA) and state medical boards. This article proposes a clinically relevant paradigm of opioid overuse pain syndrome. The goal of this article is to inform the clinicians of the complicated neurobiology of opioids. It is our hope that scientists rather than government regulators dictate the appropriate response to the epidemic of over prescription of opioids. A similar designation of "medication overuse headache" has resulted in near extinction of excessive use of opioids in the field of headache medicine.

  5. A comparative study on sub-health status and relative factors in medical and non-medical students%医学生与非医学生的亚健康状况及其相关因素的对比研究

    Institute of Scientific and Technical Information of China (English)

    邱倩仪; 马金香; 邝燕兰; 陈微微; 张怡; 赖秀娟; 罗洁玲

    2011-01-01

    目的:比较医学生与非医学生的亚健康状况及其影响因素.方法:分层随机整群抽取广州9所大学在校部分班级学生(包括医学和非医学生)并对其亚健康状况及相关因素进行问卷调查.结果:大学生的亚健康发生率为67.54%(其中医学生为67.38%,非医学生为67.68%(P>O.05)).良好的睡眠质量、重视早餐、无吸烟和无喝酒医学生优于非医学生(Pnon-medical majors) and 1420 students. By using' Sub-health Scale of Nonphysical Worker in Guangzhou' and self-designed questionnaire the data was acquired. Multivariate logistic regression was used to analyze the risk factors of sub-health status in medical and nonmedical students.Results 67. 54% of college students were sub-health status, and the sub-health rate was 67.38% in medical students and 67. 68% in non-medical students separately (x2 = 0. 015, P = 0 . 903). In good quality of sleep (x2 =5.048, P=0. 025), attaching importance to having breakfast (x2 =42. 366, P=0. 000), non-smoking ( x2 = 13. 659, P = 0.000 ) and non-alcoholic drinking ( x2 = 41. 814, P = 0.000)medical students did better than non-medical students. In having no

  6. Expansion of health insurance in Moldova and associated improvements in access and reductions in direct payments.

    Science.gov (United States)

    Hone, Thomas; Habicht, Jarno; Domente, Silviu; Atun, Rifat

    2016-12-01

    Moldova is the poorest country in Europe. Economic constraints mean that Moldova faces challenges in protecting individuals from excessive costs, improving population health and securing health system sustainability. The Moldovan government has introduced a state benefit package and expanded health insurance coverage to reduce the burden of health care costs for citizens. This study examines the effects of expanded health insurance by examining factors associated with health insurance coverage, likelihood of incurring out-of-pocket (OOP) payments for medicines or services, and the likelihood of forgoing health care when unwell. Using publically available databases and the annual Moldova Household Budgetary Survey, we examine trends in health system financing, health care utilization, health insurance coverage, and costs incurred by individuals for the years 2006-2012. We perform logistic regression to assess the likelihood of having health insurance, incurring a cost for health care, and forgoing health care when ill, controlling for socio-economic and demographic covariates. Private expenditure accounted for 55.5% of total health expenditures in 2012. 83.2% of private health expenditures is OOP payments-especially for medicines. Healthcare utilization is in line with EU averages of 6.93 outpatient visits per person. Being uninsured is associated with groups of those aged 25-49 years, the self-employed, unpaid family workers, and the unemployed, although we find lower likelihood of being uninsured for some of these groups over time. Over time, the likelihood of OOP for medicines increased (odds ratio OR = 1.422 in 2012 compared to 2006), but fell for health care services (OR = 0.873 in 2012 compared to 2006). No insurance and being older and male, was associated with increased likelihood of forgoing health care when sick, but we found the likelihood of forgoing health care to be increasing over time (OR = 1.295 in 2012 compared to 2009). Moldova has

  7. Acupuntura no Sistema Único de Saúde e a inserção de profissionais não-médicos Acupuncture in the Brazilian National Health System (SUS and the inclusion of non-medical professionals

    Directory of Open Access Journals (Sweden)

    FAS Santos

    2009-08-01

    Full Text Available CONTEXTUALIZAÇÃO: Desde o relatório final da VIII Conferência Nacional de Saúde em 1986, busca-se a introdução de práticas alternativas de assistência à saúde no âmbito dos serviços públicos de saúde. Porém, apenas em 2006, por meio da Política Nacional de Práticas Integrativas e Complementares, os profissionais não-médicos puderam atuar como acupunturistas no Sistema Único de Saúde (SUS. OBJETIVOS: Descrever a evolução da acupuntura no SUS bem como a inclusão de novos acupunturistas não-médicos. MÉTODOS: Efetuou-se um estudo exploratório e descritivo cuja fonte de dados foi o Sistema de Informações Ambulatoriais (SIA do SUS, disponibilizado pelo banco de dados do Ministério da Saúde, relativo às consultas em acupuntura realizadas por médicos e não-médicos entre 1999 e 2007, distribuindo-se os atendimentos segundo cidades e ano do atendimento. Para a análise da tendência temporal do número de atendimentos de acupuntura, foi utilizado o modelo de regressão linear simples, utilizando-se nível de significância de 5%. RESULTADOS: A análise da tendência temporal revelou um aumento significativo (p>0,001 de 1,1 consultas em acupuntura por 100 mil atendimentos ambulatoriais anualmente registrados entre os anos de 1999 e 2007. Foi observado um expressivo incremento no último ano do período estudado. Em 2007, 28% das consultas de acupuntura foram registradas por profissionais não-médicos em 41 cidades. CONCLUSÕES: Há expansão das consultas e do número de cidades que registram acupuntura no SUS no período do estudo.BACKGROUND: Since the final report of the 8th National Health Conference in 1986, the introduction of alternative healthcare practices within the scope of public health services has been sought. However, it was only in 2006, through the National Policy for Complementary and Integrative Practices, that non-medical professionals were allowed to act as acupuncturists within the Brazilian

  8. RECONCEPTUALIZING CONSENT FOR DIRECT-TO-CONSUMER HEALTH SERVICES.

    Science.gov (United States)

    Spector-Bagdady, Kayte

    2015-01-01

    The market for direct-to-consumer (DTC) health services continues to grow rapidly with former patients converting to customers for the opportunity to purchase varied diagnostic tests without the involvement of their clinician. For the first time a DTC genetic testing company is advertising health-related reports "that meet [Food and Drug Administration] standards for being clinically and scientifically valid." Ethicists and regulatory agencies alike have recognized the need for a more informed transaction in the DTC context, but how should we classify a commercial transaction for something normally protected by a duty of care? How can we assure informed agreements in an industry with terms and conditions as varied as the services performed? The doctrine of "informed consent" began as an ethical construct building on the promise of beneficence in the clinical relationship and elevating the principle of autonomy--but in the DTC context should we hold providers to legal standards of informed consent and associated medical malpractice liability, or contractual obligations where consumers would seek remedy for breach? This Article analyzes the fine balance that must be struck in an industry where companies are selling services for entertainment or non-medical purposes that possess the capacity to produce serious and disquieting medical information. It begins by reviewing current standards of consent in the clinical setting from both a legal and ethical perspective and then lays forth current standards for DTC consent using two currently controversial case studies: that of keepsake fetal ultrasound and genetic testing. DTC keepsake ultrasound and genetic testing providers attempt to de-medicalize the devices used for these procedures from their intended medical uses to non-medical uses. But while keepsake ultrasound is marketed as "intended for entertainment purposes only," it can provide medical information as an incidental finding. 23andMe currently purports to be the

  9. From Non Medical Treatment to Remove Ill Fortune to Outside Generosity and Inside Frugality:Code of Folk Beliefs in Gansu Corridor and Meaning of Legal Anthropology%从“撩病消灾”到“外慷内俭”--河西走廊的民间信仰规范及其法人类学意涵

    Institute of Scientific and Technical Information of China (English)

    王勇; 张宏

    2015-01-01

    Non medical treatment to remove ill fortune is a plain religion w hich is popular in civil society of Gansu Corridor .There is an inseparable inner link between this belief and the folk ways of outside generosity and inside frugality w hich is advocated by the farmers and herders in Gansu Corridor .What non medical treatment to remove ill fortune and outside generosity and inside frugality are ,in common ,is to disperse by dispersing ,which is a kind of survival wisdom evolved by all the generations of farmers and herders who always live in Gansu Corridor ,surrounded by the Rongdi in Mongolia ,the Western and Qinghai‐Tibet Regions .The practical effect of this kind of survival wisdom is expressed as cultivating virtue through practicing thrift , being generous to create neighborhood harmony ,agriculture and animal husbandry dependence on each other and harmonious coexistence . Systematic combing ,excavating and utilizing the local beliefs and resources in Gansu Corridor have a theoretical and practical significance for the ethnic solidarity and national construction in the northwestern region of China .%“撩病消灾”是流行于河西走廊民间社会的一种朴素的宗教信仰,这种信仰与河西走廊农牧民崇尚的“外慷内俭”的民风民俗有不可分割的内在关联。“撩病消灾”与“外慷内俭”的共通之处在于:“以散制散”,是长期居住于蒙古、西域和青藏地区之“戎狄”包围圈中的河西走廊世代农牧民历史地演化出来的一种生存智慧。这种生存智慧的实践效果集中表现为:俭以养德、慷以睦邻、农牧相依、和谐共存。系统梳理、发掘并合理利用河西走廊民间的本土信仰规范资源,对于西北地区的族群团结和国族建构具有重大的理论和现实意义。

  10. Uso não-médico de medicamentos psicoativos entre escolares do ensino fundamental e médio no Sul do Brasil Non-medical use of psychoactive medicines among elementary and high school students in Southern Brazil

    Directory of Open Access Journals (Sweden)

    Tatiane da Silva Dal Pizzol

    2006-01-01

    Full Text Available O objetivo do presente estudo é investigar a prevalência de uso não-médico de medicamentos entre escolares da rede de ensino público e privado de Passo Fundo, Rio Grande do Sul, Brasil, e sua distribuição em relação a fatores sócio-demográficos. Por meio de um delineamento transversal, foi aplicado um questionário de autopreenchimento a 5.057 estudantes a partir da quinta série do ensino fundamental até o terceiro ano do ensino médio. O questionário continha perguntas sobre o uso, sem receita médica, de anfetamínicos, ansiolíticos, barbitúricos, anticolinérgicos, opiáceos, orexígenos e anabolizantes. Da amostra, 7,7% consumiram ansiolíticos alguma vez na vida, 6,4% consumiram anfetamínicos, 2,2%, anabolizantes, e 1,1%, barbitúricos. Estudantes do sexo feminino apresentaram maior consumo de ansiolíticos e anfetamínicos, enquanto que o consumo de anabolizantes foi maior no sexo masculino. O padrão de consumo de medicamentos psicoativos é semelhante ao observado em adultos, sugerindo a necessidade de inclusão de crianças e adolescentes nas campanhas educativas para prevenção do uso indevido de medicamentos.The objective of this study is to assess the prevalence of and risk factors for the non-medical use of psychoactive medicines among students at public and private schools of Passo Fundo, Southern Brazil. A cross-sectional study was carried out using a questionnaire administered to 5,057 students from the 5th grade of elementary school to the 3rd year of high school. The questionnaire contained questions about the use of amphetamines, tranquilizers, barbiturates, anticholinergics, opioids, appetite stimulants, and anabolic steroids. Of the sample total, 7.7% had consumed tranquilizers sometime during their lives, 6.4% had used amphetamines, 2.2% had used anabolic steroids, and 1.1% had used barbiturates. Female students reported significantly greater consumption of tranquilizers and amphetamines, while anabolic

  11. Invariants of directed spaces

    DEFF Research Database (Denmark)

    Raussen, Martin

    2007-01-01

    Directed spaces are the objects of study within directed algebraic topology. They are characterised by spaces of directed paths associated to a source and a target, both elements of an underlying topological space. The algebraic topology of these path spaces and their connections are studied from...

  12. Dietary quality as a non-medical health input

    DEFF Research Database (Denmark)

    Burggraf, Christine; Teuber, Ramona; Glauben, Thomas

    2016-01-01

    The aim of this inquiry is to provide a comprehensive theoretical framework, which describes the demand for dietary quality. In our dietary health investment model, we consider the health investment character of dietary choices as well as the intertemporal health-taste trade-off. Additionally...

  13. 28 CFR 570.42 - Non-medical escorted trips.

    Science.gov (United States)

    2010-07-01

    ..., father, brother, sister, spouse, children, step-parents, and foster parents. (2) Non-emergency, non...-related functions, such an educational or religious activities, or in work-related functions. (b)...

  14. Communicating Medical Needs to Non-Medical Managers

    Science.gov (United States)

    Bacal, Kira; Miller, Robert; Doerr, Harold

    2004-01-01

    Differences in communication styles and languages between groups often lead to miscommunication, confusion, and/or frustration. Engineers, computer specialists, clinicians, and managers often utilize the English language in very different ways, with different groups using the same words to represent different concepts ("complaint" is a typical example). In addition, medical issues are often perceived as "off-nominal" and not "primary mission tasks" by managers, which can cause them to assign lower priorities to medical training time and resources. Knowledge bases differ due to variations in training and skill sets, and the goals (both immediate and long-term) of the communicators may also vary, with managers being primarily concerned with overall mission objectives, while clinicians focus on individual or group health issues. Furthermore, true communication is only possible when clinicians possess a deep understanding of mission requirements as well as the ability to communicate medical requirements on a priority basis using risk assessment, added value, and cost benefit analysis. These understandable differences may contribute to difficulties in expressing concerns and ideas in an efficient manner, particularly in projects, such as the space program or many military operations, where these varied groups must collaborate, and where the final decisions must be made by fully informed mission commanders. Methods: Three scenario-based approaches were developed utilizing decision trees and problem based learning, to help define and integrate these concepts. Results: Use of these techniques by NASA and military personnel will be presented. Discussion: To enhance communication, particularly of medical needs, one must identify the concerns and motivating factors for the other groups; for example, members of management may focus on financial concerns, a desire for risk mitigation, public perceptions, mission objectives, etc. Training clinicians to frame issues in these terms may lead to better understanding of the medical concerns by other groups.

  15. [Legal position of non-medical personnel in hospitals].

    Science.gov (United States)

    Kirschner, M H; Nebendahl, M; Russo, S G; Tecklenburg, A; Bauer, M

    2013-05-01

    There are currently many assistant professions in the German healthcare system which have either a more nursing or a more medical character. All these assistant professions have in common that as yet they do not require uniform training criteria but members of these professions undertake some aspects of medical activities. At the center lies the difficulty of more political than legal discussion on whether members of these assistant professions and also nursing personnel are allowed to or should undertake medical activities. This article illuminates the legal status quo.

  16. Non-Medical Uses of X–Rays

    Directory of Open Access Journals (Sweden)

    J. Jalal Shokouhi

    2005-08-01

    Full Text Available Introduction & Background: Deep and eminent pene-trance of x–ray, makes it useful and applicable in ra-diography and CT scanning of paintings, art pieces, ceramics, automummies, and even metal and glass objects especially in the field of archeology. In the world, 2 types of automummies have been described: ice-man and soap-man, whereas in Iran in addition to these, another rare kind of mummy namely salt-man, has also been discovered. Four salt-men have been identified till now. Patients & Methods: In winter of 1993, the first salt man was discovered. The first salt man's age was measured by carbon 14 to be 1700–1800 years which dates back to the powerful Sasanian emperor era ap-proximately 200 to 300 years before Islam. Radiogra-phy, 2D- and 3D-CT, high energy weighted spectros-copy, genetic analysis, microbiology and histology evaluations, carbon 14 studies, and DNA finger print-ing were done for him. Thin layer chromatography of his cloths colors, rare element assessment, archeol-ogy, metallurgy, and sociology investigations where also employed. Whereas the 2nd, 3rd, and 4th salt-men are under investigation by means of x-ray and CT scan the polymer specimen is under study to be syn-thesized by the S.L.A machine. Results: This investigation proposes the precious role of x-ray in radiology of artifacts, handicrafts and ar-cheology. Conclusion: In this way valuable museums are en-riched by cultural and historical remnants of previous powers and authority and this inspires the tourism industry with magnificent and splendid masterpieces of ancient civilizations. Preserving and recognizing them also helps to promote anthropological knowl-edge.

  17. Intuitive Direction Concepts

    Directory of Open Access Journals (Sweden)

    Alexander Klippel

    2015-12-01

    Full Text Available Experiments in this article test the hypothesis that formal direction models used in artificial intelligence correspond to intuitive direction concepts of humans. Cognitively adequate formal models of spatial relations are important for information retrieval tasks, cognitive robotics, and multiple spatial reasoning applications. We detail two experiments using two objects (airplanes systematically located in relation to each other. Participants performed a grouping task to make their intuitive direction concepts explicit. The results reveal an important, so far insufficiently discussed aspect of cognitive direction concepts: Intuitive (natural direction concepts do not follow a one-size-fits-all strategy. The behavioral data only forms a clear picture after participants' competing strategies are identified and separated into categories (groups themselves. The results are important for researchers and designers of spatial formalisms as they demonstrate that modeling cognitive direction concepts formally requires a flexible approach to capture group differences.

  18. Directed Energy Anechoic Chamber

    Data.gov (United States)

    Federal Laboratory Consortium — The Directed Energy Anechoic Chamber comprises a power anechoic chamber and one transverse electromagnetic cell for characterizing radiofrequency (RF) responses of...

  19. Directional radiation detectors

    Energy Technology Data Exchange (ETDEWEB)

    Dowell, Jonathan L.

    2017-09-12

    Directional radiation detectors and systems, methods, and computer-readable media for using directional radiation detectors to locate a radiation source are provided herein. A directional radiation detector includes a radiation sensor. A radiation attenuator partially surrounds the radiation sensor and defines an aperture through which incident radiation is received by the radiation sensor. The aperture is positioned such that when incident radiation is received directly through the aperture and by the radiation sensor, a source of the incident radiation is located within a solid angle defined by the aperture. The radiation sensor senses at least one of alpha particles, beta particles, gamma particles, or neutrons.

  20. Decisions Concerning Directional Dependence

    Science.gov (United States)

    von Eye, Alexander; DeShon, Richard P.

    2012-01-01

    In this rejoinder, von Eye and DeShon discuss the decision strategies proposed in their original article ("Directional Dependence in Developmental Research," this issue), as well as the ones proposed by the authors of the commentary (Pornprasertmanit and Little, "Determining Directional Dependency in Causal Associations," this issue). In addition,…

  1. Direct current transformer

    Science.gov (United States)

    Khanna, S. M.; Urban, E. W. (Inventor)

    1979-01-01

    A direct current transformer in which the primary consists of an elongated strip of superconductive material, across the ends of which is direct current potential is described. Parallel and closely spaced to the primary is positioned a transformer secondary consisting of a thin strip of magnetoresistive material.

  2. Directed Energy Weapons

    Science.gov (United States)

    2007-12-01

    the USD (I) staff to be afocalpointfor advocating improvement in all dimensions of directed energy intelligence. - The Director, Defense Inteligence ...staff to be afocalpoint for advocating iprovement in all dimensions of directed energy intelligence. The Director, Defense Inteligence Ageng7 should

  3. Direction and Description

    Science.gov (United States)

    Ben-Menahem, Yemima

    This paper deals with the dependence of directionality in the course of events-or our claims concerning such directionality-on the modes of description we use in speaking of the events in question. I argue that criteria of similarity and individuation play a crucial role in assessments of directionality. This is an extension of Davidson's claim regarding the difference between causal and explanatory contexts. The argument is based on a characterisation of notions of necessity and contingency that differ from their modal logic counterparts on the one hand, and from causality and chance on the other. I show that some types of directionality are perfectly compatible with both determinism and indeterminism at the microscopic level, and that there is no likelihood of, or advantage to, reducing such directionality to other laws or causal processes.

  4. Direct peroral cholangioscopy

    Science.gov (United States)

    Parsi, Mansour A

    2014-01-01

    Peroral cholangioscopy is an important tool for diagnosis and treatment of various biliary disorders. Peroral cholangioscopy can be performed by using a dedicated cholangioscope that is advanced through the accessory channel of a duodenoscope, or by direct insertion of a small-diameter endoscope into the bile duct. Direct peroral cholangioscopy refers to insertion of an ultraslim endoscope directly into the bile duct for visualization of the biliary mucosa and lumen. This approach provides a valuable and economic solution for diagnostic and therapeutic applications in the biliary tree. Compared to ductoscopy using a dedicated cholangioscope, the direct approach has several advantages and disadvantages. In this editorial, I discuss the advantages, disadvantages, and possible future developments pertaining to direct peroral cholangioscopy. PMID:24527174

  5. Out-of-pocket expenditure on chronic non-communicable diseases in sub-Saharan Africa: the case of rural Malawi.

    Directory of Open Access Journals (Sweden)

    Qun Wang

    Full Text Available In Sub-Saharan Africa (SSA the disease burden of chronic non-communicable diseases (CNCDs is rising considerably. Given weaknesses in existing financial arrangements across SSA, expenditure on CNCDs is often borne directly by patients through out-of-pocket (OOP payments. This study explored patterns and determinants of OOP expenditure on CNCDs in Malawi. We used data from the first round of a longitudinal household health survey conducted in 2012 on a sample of 1199 households in three rural districts in Malawi. We used a two-part model to analyze determinants of OOP expenditure on CNCDs. 475 respondents reported at least one CNCD. More than 60% of the 298 individuals who reported seeking care incurred OOP expenditure. The amount of OOP expenditure on CNCDs comprised 22% of their monthly per capita household expenditure. The poorer the household, the higher proportion of their monthly per capita household expenditure was spent on CNCDs. Higher severity of disease was significantly associated with an increased likelihood of incurring OOP expenditure. Use of formal care was negatively associated with the possibility of incurring OOP expenditure. The following factors were positively associated with the amount of OOP expenditure: being female, Alomwe and household head, longer duration of disease, CNCDs targeted through active screening programs, higher socio-economic status, household head being literate, using formal care, and fewer household members living with a CNCD within a household. Our study showed that, in spite of a context where care for CNCDs should in principle be available free of charge at point of use, OOP payments impose a considerable financial burden on rural households, especially among the poorest. This suggests the existence of important gaps in financial protection in the current coverage policy.

  6. Direct Conversion of Energy

    Energy Technology Data Exchange (ETDEWEB)

    Corliss, William R

    1964-01-01

    Topics include: direct versus dynamic energy conversion; laws governing energy conversion; thermoelectricity; thermionic conversion; magnetohydrodynamic conversion; chemical batteries; the fuel cell; solar cells; nuclear batteries; and advanced concepts including ferroelectric conversion and thermomagnetic conversion.

  7. Direct sale in USA

    OpenAIRE

    Koula, Alexandr

    2014-01-01

    This thesis deals with direct sales. The thesis discuss the connection between theoretical part of my personal experience as a door to door sales person in the US, describing a sales process, using a techniques of direct sales and communication skills in practice. It stresses the importance of understanding the basic concepts of personality and communication. The main objective of this work is a suggestion to improve the sales manual for increasing sales success of door to door sales persons ...

  8. Directed GF-spaces

    Directory of Open Access Journals (Sweden)

    F.G. Arenas

    2001-10-01

    Full Text Available In this paper we introduce the concept of directed fractal structure, which is a generalization of the concept of fractal structure (introduced by the authors. We study the relation with transitive quasiuniformities and inverse limits of posets. We define the concept of GF-compactification and apply it to prove that the Stone-Cech compactification can be obtained as the GF-compactification of the directed fractal structure associated to the Pervin quasi-uniformity.

  9. Electrohydrodynamic direct-writing

    Science.gov (United States)

    Huang, Yongan; Bu, Ningbin; Duan, Yongqing; Pan, Yanqiao; Liu, Huimin; Yin, Zhouping; Xiong, Youlun

    2013-11-01

    The electrohydrodynamic (EHD) direct-writing technique can be used to print solid/liquid straight/serpentine nanofibers onto a large-area substrate, in a direct, continuous, and controllable manner. It is a high-efficiency and cost-effective solution-processable technique to satisfy increasing demands of large-area micro/nano-manufacturing. It is ground-breaking to direct-write sub-100 nm fibers on a rigid/flexible substrate using organic materials. A comprehensive review is presented on the research and developments related to the EHD direct-writing technique and print heads. Many developments have been presented to improve the controllability of the electrospun fibers to form high-resolution patterns and devices. EHD direct-writing is characterized by its non-contact, additive and reproducible processing, high resolution, and compatibility with organic materials. It combines dip-pen, inkjet, and electrospinning by providing the feasibility of controllable electrospinning for sub-100 nm nanofabrication, and overcomes the drawbacks of conventional electron-beam lithography, which is relatively slow, complicated and expensive.

  10. Direct conversion technology

    Energy Technology Data Exchange (ETDEWEB)

    Massier, P.F.; Back, L.H.; Ryan, M.A.; Fabris, G.

    1992-01-07

    The overall objective of the Direct Conversion Technology task is to develop an experimentally verified technology base for promising direct conversion systems that have potential application for energy conservation in the end-use sectors. This report contains progress of research on the Alkali Metal Thermal-to-Electric Converter (AMTEC) and on the Two-Phase Liquid-Metal MHD Electrical Generator (LMMHD) for the period January 1, 1991 through December 31, 1991. Research on AMTEC and on LMMHD was initiated during October 1987. Reports prepared on previous occasions (Refs. 1--5) contain descriptive and performance discussions of the following direct conversion concepts: thermoelectric, pyroelectric, thermionic, thermophotovoltaic, thermoacoustic, thermomagnetic, thermoelastic (Nitionol heat engine); and also, more complete descriptive discussions of AMTEC and LMMHD systems.

  11. Directional loudness perception

    DEFF Research Database (Denmark)

    Sivonen, Ville Pekka

    reaches the listener affect its perceived loudness. The results obtained in a series of listening experiments show that loudness depends considerably on direction for a variety of sound stimuli. Furthermore, these directional dependencies could be largely accounted for by determining binaural at......Loudness, the perceived intensity of sound, is a fundamental attribute in psychoacoustics. An immense body of literature on loudness has been accumulated, and based on the reported findings, models for predicting loudness from monophonic, acoustical measurements of sound pressure have been...... developed. The research and modeling of loudness have mainly been concerned with the temporal and spectral aspects of sounds, while the spatial aspects have mostly been overlooked. This PhD thesis investigates the spatial aspects of loudness perception, namely, how does the direction from which a sound...

  12. Socio-economic determinants of household out-of-pocket payments on healthcare in Pakistan

    Directory of Open Access Journals (Sweden)

    Muhammad Malik Ashar

    2012-09-01

    Full Text Available Abstract Background Out-of-pocket (OOP payment on healthcare is dominant mode of financing in developing countries. In Pakistan it is 67% of total expenditure on healthcare. Analysis of determinants of OOP health expenditure is a key aspect of equity in healthcare financing. It helps to formulate an effective health policy. Evidence on OOP in Pakistan is sparse. This paper attempts to fill this research gap. Methods We estimated determinants of OOP payments on healthcare in Pakistan. We used data sets of Pakistan Household Integrated Economic Survey (HIES and Pakistan Standard of Living Measurement (PSLM Survey for the year 2004-05. We developed a multiple regression model for the determinants of OOP payments using methods of Ordinary Least Square (OLS. We mainly used social, economic, demographic and health variables in our analysis. Results Median household OOP healthcare in the year 2004-05 was Pakistani Rupees (PKR 2500 (US$ 41.99 in 2004-05. Household non-food expenditure was the single highest significant predictor of household OOP health expenditure. Household features like literate head and spouse, at least one obstetric delivery in last three years, unsafe water, unhygienic toilet and household belonging to Khyber Pukhtonkhwa (KPK province were significant positive predictors of OOP payments. Households with male head, bricks used in housing construction, household with at least one child and no elderly, and head of household in a white collar profession were negative predictors of OOP payments. Conclusion Our analysis confirms earlier findings that economic status and number of old aged members are significant positive predictors of OOP payments. This association can direct government to enhance allocations to healthcare and to include program focusing on non-communicable diseases. Our findings suggest further research to explore beneficiaries of government healthcare programs and determinants of high OOP payments by household residing

  13. Modelling directional solidification

    Science.gov (United States)

    Wilcox, William R.; Regel, Liya L.

    1994-01-01

    This grant, NAG8-831, was a continuation of a previous grant, NAG8-541. The long range goal of this program has been to develop an improved understanding of phenomena of importance to directional solidification, in order to enable explanation and prediction of differences in behavior between solidification on Earth and in space. Emphasis in the recently completed grant was on determining the influence of perturbations on directional solidification of InSb and InSb-GaSb alloys. In particular, the objective was to determine the influence of spin-up/spin-down (ACRT), electric current pulses and vibrations on compositional homogeneity and grain size.

  14. The direction of time

    CERN Document Server

    Reichenbach, Hans

    1999-01-01

    Ever a source of philosophical conjecture and debate, the concept of time represents the beating heart of physics. This final work by the distinguished physicist Hans Reichenbach represents the culmination and integration of a lifetime's philosophical contributions and inquiries into the analysis of time. The result is an outstanding overview of such qualitative, or topological, attributes of time as order and direction.Beginning with a discussion of the emotive significance of time, Reichenbach turns to an examination of the time order of mechanics, the time direction of thermodynamics and m

  15. Incretin secretion: direct mechanisms

    DEFF Research Database (Denmark)

    Balk-Møller, Emilie; Holst, Jens Juul; Kuhre, Rune Ehrenreich

    2014-01-01

    The incretin hormones glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) are secreted from gastro-intestinal K- and L-cells, respectively, and play an important role in post-prandial blood glucose regulation. They do this by direct stimulation of the pancreatic β...... enzyme responsible for incretin degradation (dipeptidyl peptidase-4) is inhibited (drugs are already on the market) while the secretion of endogenous GLP-1 secretion is stimulated at the same time may prove particularly rewarding. In this section we review current knowledge on the mechanisms for direct...

  16. Direct policy search

    DEFF Research Database (Denmark)

    Heidrich-Meisner, V.; Igel, Christian

    2010-01-01

    process. Exploration is realized by stochastic perturbations, which can be applied at different levels. When considering direct policy search in the space of neural network policies, exploration can be applied on the synaptic level or on the level of neuronal activity. We propose neuroevolution strategies...... (NeuroESs) for direct policy search in RL. Learning using NeuroESs can be interpreted as modelling of extrinsic perturbations on the level of synaptic weights. In contrast, policy gradient methods (PGMs) can be regarded as intrinsic perturbation of neuronal activity. We compare these two approaches...

  17. [New direct restorative materials].

    Science.gov (United States)

    Hickel, R; Dasch, W; Janda, R; Tyas, M; Anusavice, K

    1999-04-01

    People worldwide have become increasingly aware of the potential adverse effects on the environment, of pollution control and of toxic effects of food, drugs and biomaterials. Amalgam and its potential toxic side effects (still scientifically unproven) continue to be discussed with increasing controversy by the media in some countries. Consequently, new direct restorative materials are now being explored by dentists, materials scientists and patients who are searching for the so-called 'amalgam substitute' or 'amalgam alternative'. From a critical point of view some of the new direct restorative materials are good with respect in aesthetics, but all material characteristics must be considered, such as mechanical properties, biological effects, and longterm clinical behaviour.

  18. A Novel Coupling Metrics Measure difference between Inheritance and Interface to find better OOP Paradigm using C#

    Directory of Open Access Journals (Sweden)

    Mr. Narendra Pal Singh Rathore Prof. Ravindra Gupta

    2011-10-01

    Full Text Available A large numbers of metrics have been proposed for measuring properties of object-oriented software such as size, inheritance, cohesion and coupling. The coupling metrics presented in this paper exploring the difference between inheritance and interface programming. This paper presents a measurement to measure coupling between object (CBO, number of associations between classes (NASSocC, number of dependencies in metric (NDepIN , number of dependencies out metric (NDepOut and Number of children (NOC in object oriented programming. A measurement is done for C# inheritance and interface programs. The metric values of class inheritance and interface prove which program is good to use and beneficial for C# developers.

  19. Directions for further research

    DEFF Research Database (Denmark)

    Minsaas, Atle; Psaraftis, Harilaos N.

    2015-01-01

    chapter of this book we discuss directions for further research in this area. We do so by taking stock of (1) related recommendations of project SuperGreen, and (2) related activities mainly in European research. Links between research and policy-making as two activities that should go hand in hand...

  20. Advanced directives: open issues

    Directory of Open Access Journals (Sweden)

    Gabriella Negrini

    2013-05-01

    Full Text Available BACKGROUND In Italy Advanced directives have not been regulated by law yet. Moreover, there is a confusion of concepts: advanced directives, refusal of treatment, medical futility and euthanasia are not synonymous.DISCUSSION The following aspects are then discussed: object of directives; elapse of time between their expression and their application; knowledge of the directives and their obligatory nature. The refusal of a treatment that can save a person’s life is a critical subject. There are different ethical points of view: according to lay ethics, the patient’s self-determination prevails; the religious viewpoint, instead, says that life is a gift which we cannot dispose of. In any case, the patient will be confronted with the professional autonomy of the doctor. Should the doctor save a patient’s life in any case or should he achieve best clinical practice, in respect of his will? The doctor should interpret the patient’s will but with caution and judgment. An exemption from responsibility should be provided by law for doctors who respect patient’s living will.

  1. Direct Sulfation of Limestone

    DEFF Research Database (Denmark)

    Hu, Guilin; Dam-Johansen, Kim; Wedel, Stig

    2007-01-01

    The direct sulfation of limestone was studied in a laboratory fixed-bed reactor. It is found that the direct sulfation of limestone involves nucleation and crystal grain growth of the solid product (anhydrite). At 823 K and at low-conversions (less than about 0.5 %), the influences of SO2, O-2...... and CO2 on the direct sulfation of limestone corresponds to apparent reaction orders of about 0.2, 0.2 and -0.5, respectively. Water is observed to promote the sulfation reaction and increase the apparent reaction orders of SO2 and O-2. The influence of O-2 at high O-2 concentrations (> about 15...... %) becomes negligible. In the temperature interval from 723 K to 973 K, an apparent activation energy of about 104 kJ/mol is observed for the direct sulfation of limestone. At low temperatures and low conversions, the sulfation process is most likely under mixed control by chemical reaction and solid...

  2. Direct vision internal urethrotomy

    DEFF Research Database (Denmark)

    Jakobsen, H; Willumsen, H; Søndergaard Jensen, L

    1984-01-01

    During a five-year period, direct vision internal urethrotomy was used for the treatment of urethral strictures in 34 men. After the primary operation the patients were followed for an average period of 29 months (range 3-73 months). During this period 53% of the patients were found to have one...

  3. Directed and diode percolation

    Science.gov (United States)

    Redner, S.

    1982-03-01

    We study the novel percolation phenomena that occur in random-lattice networks consisting of resistor-like and diode-like bonds. Resistor bonds connect or "transmit information" in either direction along their length, while diodes connect in one direction only. We first treat the special case of directed bond percolation, in which the diodes are aligned along a preferred axis. Mean-field theory shows that clusters become extremely anisotropic near the percolation transition and that their shapes are characterized by two correlation lengths, one parallel and one transverse to the preferred axis. These lengths diverge with exponents ν∥=1 and ν⊥=12, respectively, from which we can show that the upper critical dimension for this system must be five. We also treat a more general random network on the square lattice containing resistors and diodes of arbitrary orientation. Duality arguments are applied to obtain exact results for the location of phase transitions in this system. We then use a position-space renormalization-group approach to map out the phase diagram and calculate critical exponents. This system has an isotropic percolating phase, and phases which percolate in only one direction. Novel types of transitions occur between these phases, in which the diode orientation plays a fundamental role. These percolating phases meet with the nonpercolating phase along a line of multicritical points, where concentration and orientational fluctuations are simultaneously critical.

  4. The Directed Case Method.

    Science.gov (United States)

    Cliff, William H.; Curtin, Leslie Nesbitt

    2000-01-01

    Provides an example of a directed case on human anatomy and physiology. Uses brief real life newspaper articles and clinical descriptions of medical reference texts to describe an actual, fictitious, or composite event. Includes interrelated human anatomy and physiology topics in the scenario. (YDS)

  5. Polymer Directed Protein Assemblies

    Directory of Open Access Journals (Sweden)

    Patrick van Rijn

    2013-05-01

    Full Text Available Protein aggregation and protein self-assembly is an important occurrence in natural systems, and is in some form or other dictated by biopolymers. Very obvious influences of biopolymers on protein assemblies are, e.g., virus particles. Viruses are a multi-protein assembly of which the morphology is dictated by poly-nucleotides namely RNA or DNA. This “biopolymer” directs the proteins and imposes limitations on the structure like the length or diameter of the particle. Not only do these bionanoparticles use polymer-directed self-assembly, also processes like amyloid formation are in a way a result of directed protein assembly by partial unfolded/misfolded biopolymers namely, polypeptides. The combination of proteins and synthetic polymers, inspired by the natural processes, are therefore regarded as a highly promising area of research. Directed protein assembly is versatile with respect to the possible interactions which brings together the protein and polymer, e.g., electrostatic, v.d. Waals forces or covalent conjugation, and possible combinations are numerous due to the large amounts of different polymers and proteins available. The protein-polymer interacting behavior and overall morphology is envisioned to aid in clarifying protein-protein interactions and are thought to entail some interesting new functions and properties which will ultimately lead to novel bio-hybrid materials.

  6. Polar Direct Drive

    Science.gov (United States)

    Skupsky, S.

    2003-10-01

    Direct drive offers the potential of higher target gain on the National Ignition Facility (NIF) than x-ray drive: The initial direct-drive target design had a 1-D gain of 45 and consisted primarily of a pure cryogenic DT shell. Using the expected levels of target and laser nonuniformities for the NIF, two-dimensional (2-D) hydrodynamic simulations predicted target gains around 30.(P.W. McKenty et al.), Phys. Plasmas 8, 2315 (2001). More-recent designs have shown that higher target gains could be obtained by replacing a portion of the DT shell with ``wetted'' CH foam and by using adiabat shaping: (1) Higher-Z material (C) in the foam increases laser absorption by about 40% (from 60% absorption to 85%).(S. Skupsky et al.), in Inertial Fusion Sciences and Applications 2001, edited by K. Tanaka et al. (Elsevier, Paris, 2002), p. 240. (2) Adiabat shaping allows the main portion of the fuel to be placed on a lower adiabat without compromising target stability.(V.N. Goncharov et al.), Phys. Plasmas 10, 1906 (2003). These direct-drive concepts can be tested on the NIF, long before that facility is converted to a direct-drive (spherically symmetric) irradiation configuration. Using the NIF x-ray-drive beam configuration, some of the near-polar beams could be pointed to better illuminate the target's equator. These more-oblique, equatorial beams will have lower absorption and reduced drive efficiency than the polar beams. One strategy to compensate for the difference in polar and equatorial drive is to reduce the irradiation at the poles and employ different pulse shapes to accommodate the time-dependent variations in drive and absorption. This concept of polar direct drive (PDD) has been studied using the 2-D hydrocode DRACO to determine the requirements for achieving ignition and moderate target gain for the NIF. Experiments on the OMEGA laser will examine the effects of oblique irradiation on target drive. Results of simulations for different direct-drive target designs

  7. Direct and Indirect Costs of Asthma Management in Greece: An Expert Panel Approach.

    Science.gov (United States)

    Souliotis, Kyriakos; Kousoulakou, Hara; Hillas, Georgios; Bakakos, Petros; Toumbis, Michalis; Loukides, Stelios; Vassilakopoulos, Theodoros

    2017-01-01

    Asthma is a major cause of morbidity and mortality and is associated with significant economic burden worldwide. The objectives of this study were to map current resource use associated with the disease management and to estimate the annual direct and indirect costs per adult patient with asthma. A Delphi panel with seven leading pulmonologists was conducted. A semistructured questionnaire was developed to elicit data on resource use and treatment patterns. Unit costs from official, published sources were subsequently assigned to resource use to estimate direct medical costs. Indirect costs were estimated as number of work loss days. Cost base year was 2015, and the perspective adopted was that of the National Organization of Health Care Services Provision, as well as the societal. Patients with asthma are mainly managed by pulmonologists (71.4%) and secondarily by general practitioners and internists (28.6%). The annual cost of managing exacerbations was estimated at €273.1, while maintenance costs were estimated at €1,100.2 per year. Total costs of managing asthma per patient per year were estimated at €2,281.8, 64.4% of which represented direct medical costs. Of the direct costs, pharmaceutical treatment was the key driver, accounting for 63.9 and 41.2% of direct and total costs, respectively. Direct non-medical costs (patient travel and waiting time) were estimated at €152.3. Indirect costs accounted for 28.9% of total costs. Asthma is a chronic condition, the management of which constrains the already limited Greek health care resources. The increasing prevalence of the disease raises concerns as it could translate per patient costs into a significant burden for the Greek health care system. Thus, the prevention, self-management, and improved quality of care for asthma should find a place in the health policy agenda in Greece.

  8. Direction sensitive neutron detector

    Energy Technology Data Exchange (ETDEWEB)

    Ahlen, Steven; Fisher, Peter; Dujmic, Denis; Wellenstein, Hermann F.; Inglis, Andrew

    2017-01-31

    A neutron detector includes a pressure vessel, an electrically conductive field cage assembly within the pressure vessel and an imaging subsystem. A pressurized gas mixture of CF.sub.4, .sup.3He and .sup.4He at respective partial pressures is used. The field cage establishes a relatively large drift region of low field strength, in which ionization electrons generated by neutron-He interactions are directed toward a substantially smaller amplification region of substantially higher field strength in which the ionization electrons undergo avalanche multiplication resulting in scintillation of the CF.sub.4 along scintillation tracks. The imaging system generates two-dimensional images of the scintillation patterns and employs track-finding to identify tracks and deduce the rate and direction of incident neutrons. One or more photo-multiplier tubes record the time-profile of the scintillation tracks permitting the determination of the third coordinate.

  9. [Direct biosynthesis of ethylene].

    Science.gov (United States)

    Sun, Zhilan; Chen, Yifeng

    2013-10-01

    Ethylene is the most widely used petrochemical feedstock globally. The development of bio-ethylene is essential due to limited fossil fuels and rising oil prices. Bio-ethylene is produced primarily by the dehydration of ethanol, but can alternatively be directly produced from ethylene biosynthesis pathways in plants, algae, or microorganisms by using cheap and renewable substrates. This review addressed the biosynthesis of ethylene in plants and microorganisms, the characterization of key enzymes, genetic engineering strategies for ethylene biosynthesis in microorganisms, and evaluated its perspective and successful cases toward the industrial application. The direct production of bio-ethylene from a biological process in situ is promising to supplement and even replace the petrochemical ethylene production.

  10. Direct photons at FAIR

    Energy Technology Data Exchange (ETDEWEB)

    Baeuchle, Bjoern [Frankfurt Institute for Advanced Studies (FIAS), Ruth-Moufang-Str. 1, D-60438 Frankfurt am Main (Germany); Bleicher, Marcus; Grimm, Andreas [Frankfurt Institute for Advanced Studies (FIAS), Ruth-Moufang-Str. 1, D-60438 Frankfurt am Main (Germany); Frankfurt Univ. (Germany). Inst. fuer Theoretische Physik

    2013-07-01

    Photons, as all electromagnetic probes, can give direct access to the hot and dense phase of a heavy-ion reaction. We show calculations of direct photon emission at SiS100- and SiS-300 energies with the UrQMD-hybrid model. UrQMD is a full microscopic+macroscopic transport/fluid-dynamics hybrid model with hadron- and string-driven equilibration phase, a full (3+1)-dimensional fluiddynamic hot and dense phase and a hadronic after-burner. Unequilibrated matter at high rapidity is preserved during the fluid phase. A strong emphasis is set on the impact of viscosity and Equation of State at zero and non-zero baryon density to the spectra and flow patterns of thermal and non-thermal photons in A+A-collisions at the colliding systems relevant for FAIR.

  11. On directed coverings

    DEFF Research Database (Denmark)

    Fajstrup, Lisbeth

    In [1], we study coverings in the setting of directed topology. Unfortunately, there is a condition missing in the definition of a directed covering. Some of the results in [1] require this extra condition and in fact it was claimed to follow from the original definition. It is the purpose...... of this note to give the right definition and point out how this affects the statements in that paper. Moreover, we give an example of a dicovering in the sense of [1], which does not satisfy the extra condition. Fortunately, with the extra condition, the subsequent results are now correct. [1] L. Fajstrup......, Dicovering spaces, Homology Homotopy Appl. 5 (2003), no. 2, 1-17....

  12. Direct Olive Oil Analysis

    OpenAIRE

    2002-01-01

    The practical impact of “direct analysis” is undeniable as it strong contributes to enhance the so-called productive analytical features such as expeditiousness, reduction of costs and minimisation of risks for the analysts and environment. The main objective is to establish a reliable bypass to the conventional preliminary operations of the analytical process. This paper offers a systematic approach in this context and emphasises the great field of action of...

  13. Site-directed mutagenesis.

    Science.gov (United States)

    Bachman, Julia

    2013-01-01

    Site-directed mutagenesis is a PCR-based method to mutate specified nucleotides of a sequence within a plasmid vector. This technique allows one to study the relative importance of a particular amino acid for protein structure and function. Typical mutations are designed to disrupt or map protein-protein interactions, mimic or block posttranslational modifications, or to silence enzymatic activity. Alternatively, noncoding changes are often used to generate rescue constructs that are resistant to knockdown via RNAi.

  14. Directional Solidification of Ledeburite

    Directory of Open Access Journals (Sweden)

    M. Trepczyńska-Łent

    2013-07-01

    Full Text Available Directional solidification of ledeburite was realised out using a Bridgman’s device. The growth rate for movement sample v=83.3 μm/s was used. In one sample the solidification front was freezing. The value of temperature gradient in liquid at the solidification front was determined. Interfacial distance λ on the samples was measured with NIS-Elements application for image analysis.

  15. Direct hydrocarbon fuel cells

    Science.gov (United States)

    Barnett, Scott A.; Lai, Tammy; Liu, Jiang

    2010-05-04

    The direct electrochemical oxidation of hydrocarbons in solid oxide fuel cells, to generate greater power densities at lower temperatures without carbon deposition. The performance obtained is comparable to that of fuel cells used for hydrogen, and is achieved by using novel anode composites at low operating temperatures. Such solid oxide fuel cells, regardless of fuel source or operation, can be configured advantageously using the structural geometries of this invention.

  16. Future directions for QCD

    Energy Technology Data Exchange (ETDEWEB)

    Bjorken, J.D.

    1996-10-01

    New directions for exploring QCD at future high-energy colliders are sketched. These include jets within jets. BFKL dynamics, soft and hard diffraction, searches for disoriented chiral condensate, and doing a better job on minimum bias physics. The new experimental opportunities include electron-ion collisions at HERA, a new collider detector at the C0 region of the TeVatron, and the FELIX initiative at the LHC.

  17. Direct Olive Oil Analysis

    OpenAIRE

    Peña, F.; Cárdenas, S.; Gallego, M.; Valc?rcel, M.

    2002-01-01

    The practical impact of “direct analysis” is undeniable as it strong contributes to enhance the so-called productive analytical features such as expeditiousness, reduction of costs and minimisation of risks for the analysts and environment. The main objective is to establish a reliable bypass to the conventional preliminary operations of the analytical process. This paper offers a systematic approach in this context and emphasises the great field of action of...

  18. Direct imaging of exoplanets.

    Science.gov (United States)

    Lagrange, Anne-Marie

    2014-04-28

    Most of the exoplanets known today have been discovered by indirect techniques, based on the study of the host star radial velocity or photometric temporal variations. These detections allowed the study of the planet populations in the first 5-8 AU from the central stars and have provided precious information on the way planets form and evolve at such separations. Direct imaging on 8-10 m class telescopes allows the detection of giant planets at larger separations (currently typically more than 5-10 AU) complementing the indirect techniques. So far, only a few planets have been imaged around young stars, but each of them provides an opportunity for unique dedicated studies of their orbital, physical and atmospheric properties and sometimes also on the interaction with the 'second-generation', debris discs. These few detections already challenge formation theories. In this paper, I present the results of direct imaging surveys obtained so far, and what they already tell us about giant planet (GP) formation and evolution. Individual and emblematic cases are detailed; they illustrate what future instruments will routinely deliver for a much larger number of stars. I also point out the limitations of this approach, as well as the needs for further work in terms of planet formation modelling. I finally present the progress expected in direct imaging in the near future, thanks in particular to forthcoming planet imagers on 8-10 m class telescopes.

  19. [Advance directives. Representatives' opinions].

    Science.gov (United States)

    Busquets I Font, J M; Hernando Robles, P; Font I Canals, R; Diestre Ortin, G; Quintana, S

    The use and usefulness of Advance Directives has led to a lot of controversy about their validity and effectiveness. Those areas are unexplored in our country from the perspective of representatives. To determine the opinion of the representatives appointed in a registered Statement of Advance Directives (SAD) on the use of this document. Telephone survey of representatives of 146 already dead people and who, since February 2012, had registered a SAD document. More the two-thirds (98) of respondents recalled that the SAD was consulted, with 86 (58.9%) saying that their opinion as representative was consulted, and 120 (82.1%) believe that the patient's will was respected. Of those interviewed, 102 (69.9%) believe that patients who had previously planned their care using a SAD had a good death, with 33 (22.4%) saying it could have been better, and 10 (6.9%) believe they suffered greatly. The SAD were mostly respected and consulted, and possibly this is related to the fact that most of the representatives declare that the death of those they represented was perceived as comfortable. It would be desirable to conduct further studies addressed at health personnel in order to know their perceptions regarding the use of Advance Directives in the process of dying. Copyright © 2016 SECA. Publicado por Elsevier España, S.L.U. All rights reserved.

  20. Directional Antineutrino Detection

    Science.gov (United States)

    Safdi, B. R.; Suerfu, J.

    2014-12-01

    We propose the first truly directional antineutrino detector for antineutrinos near the threshold for the inverse beta decay (IBD) of hydrogen, with potential applications including the spatial mapping of geo-neutrinos, searches for stellar antineutrinos, and the monitoring of nuclear reactors. The detector consists of adjacent and separated target and neutron-capture layers. The IBD events, which result in a neutron and a positron, take place in the target layers. These layers are thin enough so that the neutrons escape without scattering elastically. The neutrons are detected in the thicker neutron-capture layers. The location of the IBD event is determined from the energy deposited by the positron as it slows in the medium and from the two gamma rays that come from the positron annihilation. Since the neutron recoils in the direction of the antineutrino's motion, a line may then be drawn between the IBD event location and the neutron-capture location to approximate the antineutrino's velocity. In some events, we may even measure the positron's velocity, which further increases our ability to reconstruct the antineutrino's direction of motion. Our method significantly improves upon previous methods by allowing the neutron to freely travel a long distance before diffusing and being captured. Moreover, our design is a straightforward modification of existing antineutrino detectors; a prototype could easily be built with existing technology. We verify our design through Monte Carlo simulations in Geant4, using commercially-available boron-loaded plastic scintillators for the target and neutron-capture layer materials. We are able to discriminate from background using multiple coincidence signatures within a short, ~microsecond time interval. We conclude that the detector could likely operate above ground with minimal shielding.

  1. Omni-directional railguns

    Energy Technology Data Exchange (ETDEWEB)

    Shahinpoor, M.

    1994-12-31

    This invention is comprised of a device for electromagetically accelerating projectiles. The invention features two parallel conducting circular plates, a plurality of electrode connections to both upper and lower plates, a support base, and a projectile magazine. A projectile is spring-loaded into a firing position concentrically located between the parallel plates. A voltage source is applied to the plates to cause current to flow in directions defined by selectable, discrete electrode connections on both upper and lower plates. Repulsive Lorentz forces are generated to eject the projectile in a 360 degree range of fire.

  2. AngularJS directives

    CERN Document Server

    Vanston, Alex

    2013-01-01

    This book uses a practical, step-by-step approach, starting with how to build directives from the ground up before moving on to creating web applications comprised of multiple modules all working together to provide the best user experience possible.This book is intended for intermediate JavaScript developers who are looking to enhance their understanding of single-page web application development with a focus on AngularJS and the JavaScript MVC frameworks.It is expected that readers will understand basic JavaScript patterns and idioms and can recognize JSON formatted data.

  3. Direct reading inductance meter

    Science.gov (United States)

    Kolby, R. B. (Inventor)

    1977-01-01

    A direct reading inductance meter comprised of a crystal oscillator and an LC tuned oscillator is presented. The oscillators function respectively to generate a reference frequency, f(r), and to generate an initial frequency, f(0), which when mixed produce a difference equal to zero. Upon connecting an inductor of small unknown value in the LC circuit to change its resonant frequency to f(x), a difference frequency (f(r)-f(x)) is produced that is very nearly a linear function of the inductance of the inductor. The difference frequency is measured and displayed on a linear scale in units of inductance.

  4. Omni-directional railguns

    Science.gov (United States)

    Shahinpoor, M.

    1995-07-25

    A device is disclosed for electromagnetically accelerating projectiles. The invention features two parallel conducting circular plates, a plurality of electrode connections to both upper and lower plates, a support base, and a projectile magazine. A projectile is spring-loaded into a firing position concentrically located between the parallel plates. A voltage source is applied to the plates to cause current to flow in directions defined by selectable, discrete electrode connections on both upper and lower plates. Repulsive Lorentz forces are generated to eject the projectile in a 360 degree range of fire. 4 figs.

  5. On Direct Social Perception.

    Science.gov (United States)

    Spaulding, Shannon

    2015-11-01

    Direct Social Perception (DSP) is the idea that we can non-inferentially perceive others' mental states. In this paper, I argue that the standard way of framing DSP leaves the debate at an impasse. I suggest two alternative interpretations of the idea that we see others' mental states: others' mental states are represented in the content of our perception, and we have basic perceptual beliefs about others' mental states. I argue that the latter interpretation of DSP is more promising and examine the kinds of mental states that plausibly could satisfy this version of DSP. Copyright © 2015 Elsevier Inc. All rights reserved.

  6. DISE: directed sphere exclusion.

    Science.gov (United States)

    Gobbi, Alberto; Lee, Man-Ling

    2003-01-01

    The Sphere Exclusion algorithm is a well-known algorithm used to select diverse subsets from chemical-compound libraries or collections. It can be applied with any given distance measure between two structures. It is popular because of the intuitive geometrical interpretation of the method and its good performance on large data sets. This paper describes Directed Sphere Exclusion (DISE), a modification of the Sphere Exclusion algorithm, which retains all positive properties of the Sphere Exclusion algorithm but generates a more even distribution of the selected compounds in the chemical space. In addition, the computational requirement is significantly reduced, thus it can be applied to very large data sets.

  7. Direct olive oil analysis

    Directory of Open Access Journals (Sweden)

    Peña, F.

    2002-03-01

    Full Text Available The practical impact of “direct analysis” is undeniable as it strong contributes to enhance the so-called productive analytical features such as expeditiousness, reduction of costs and minimisation of risks for the analysts and environment. The main objective is to establish a reliable bypass to the conventional preliminary operations of the analytical process. This paper offers a systematic approach in this context and emphasises the great field of action of direct methodologies in the routine analysis of olive oil. Two main types of methodologies are considered. On the one hand, the direct determination of volatile components is systematically considered. On the other hand, simple procedures to automatically implement the preliminary operations of the oil analysis using simple devices in which the sample is directly introduced with/without a simple dilution are present and discussed.El impacto práctico del análisis directo es tan innegable como que el contribuye decisivamente a mejorar las denominadas características analíticas relacionadas con la productividad como la rapidez, la reducción de costes y la minimización de riesgos para los analistas y el ambiente. El principal objetivo es establecer un adecuado "bypass" a las operaciones convencionales preliminares del proceso analítico. Este artículo ofrece una propuesta sistemática en este contexto y resalta el gran campo de acción de las metodologías directas en los análisis de rutina del aceite de oliva. Se analizan los dos tipos principales de metodologías. Por una lado, se analiza la determinación directa de los compuestos volátiles. Por el otro, se presentan y discuten los procedimientos simples para implementar automáticamente las operaciones preliminares del análisis del aceite usando sistemas simples en los que la muestra se introduce directamente con/sin un dilución simple.

  8. Psychiatric Advance Directives: Getting Started

    Science.gov (United States)

    ... More... Home Getting Started National Resource Center on Psychiatric Advance Directives - Getting Started Getting Started Psychiatric advance directives (PADs) are relatively new legal instruments ...

  9. Direct Production of Copper

    Science.gov (United States)

    Victorovich, G. S.; Bell, M. C.; Diaz, C. M.; Bell, J. A. E.

    1987-09-01

    The use of commercially pure oxygen in flash smelting a typical chalcopyrite concentrate or a low grade comminuted matte directly to copper produces a large excess of heat. The heat balance is controlled by adjusting the calorific value of the solid feed. A portion of the sulfide material is roasted to produce a calcine which is blended with unroasted material, and the blend is then autogeneously smelted with oxygen and flux directly to copper. Either iron silicate or iron calcareous slags are produced, both being subject to a slag cleaning treatment. Practically all of the sulfur is contained in a continuous stream of SO2 gas, most of which is strong enough for liquefaction. A particularly attractive feature of these technologies is that no radically new metallurgical equipment needs to be developed. The oxygen smelting can be carried out not only in the Inco type flash furnace but in other suitable smelters such as cyclone furnaces. Another major advantage stems from abolishion of the ever-troublesome converter aisle, which is replaced with continuous roasting of a fraction of the copper sulfide feed.

  10. Remote direct memory access

    Science.gov (United States)

    Archer, Charles J.; Blocksome, Michael A.

    2012-12-11

    Methods, parallel computers, and computer program products are disclosed for remote direct memory access. Embodiments include transmitting, from an origin DMA engine on an origin compute node to a plurality target DMA engines on target compute nodes, a request to send message, the request to send message specifying a data to be transferred from the origin DMA engine to data storage on each target compute node; receiving, by each target DMA engine on each target compute node, the request to send message; preparing, by each target DMA engine, to store data according to the data storage reference and the data length, including assigning a base storage address for the data storage reference; sending, by one or more of the target DMA engines, an acknowledgment message acknowledging that all the target DMA engines are prepared to receive a data transmission from the origin DMA engine; receiving, by the origin DMA engine, the acknowledgement message from the one or more of the target DMA engines; and transferring, by the origin DMA engine, data to data storage on each of the target compute nodes according to the data storage reference using a single direct put operation.

  11. Direct Dimethyl Ether Synthesis

    Institute of Scientific and Technical Information of China (English)

    Takashi Ogawa; Norio Inoue; Tutomu Shikada; Yotaro Ohno

    2003-01-01

    Dimethyl ether (DME) is a clean and economical alternative fuel which can be produced from natural gas through synthesis gas. The properties of DME are very similar to those of LP gas. DME can be used for various fields as a fuel such as power generation, transportation, home heating and cooking,etc. It contains no sulfur or nitrogen. It is not corrosive to any metal and not harmful to human body. An innovative process of direct synthesis of DME from synthesis gas has been developed. Newly developed catalyst in a slurry phase reactor gave a high conversion and high selectivity of DME production. One and half year pilot scale plant (5 tons per day) testing, which was supported by METI, had successfully finished with about 400 tons DME production.

  12. Directional Antineutrino Detection

    CERN Document Server

    Safdi, Benjamin R

    2014-01-01

    We propose the first truly directional antineutrino detector for antineutrinos above the hydrogen inverse beta decay (IBD) threshold, with potential applications including monitoring for nuclear nonproliferation, spatially mapping geo-neutrinos, characterizing the diffuse supernova neutrino background, and searching for new physics in the neutrino sector. The detector consists of adjacent and separated target and capture scintillator planes. IBD events take place in the target layers, which are thin enough to allow the neutrons to escape without scattering elastically. The neutrons are detected in the thicker, boron-loaded capture layers. The location of the IBD event and the momentum of the positron are determined by tracking the positron's trajectory through the detector. Our design is a straightforward modification of existing antineutrino detectors; a prototype could be built with existing technology.

  13. Direct diverticular inguinal hernia

    Energy Technology Data Exchange (ETDEWEB)

    Ekberg, O.; Kullenberg, K.

    Nineteen patients with direct diverticular inguinal hernia (DDIH) were examined with herniography and surgically explored. A lump medially in the groin and pain were the prominent clinical manifestations in 18 patients. Physical examination indicated the presence of a DDIH in 6 patients. In 16 patients herniography revealed hernial sacs protruding from the supravesical fossa in 5 and from the medial inguinal fossa in 11. At operation a circumscribed defect was found in the transverse fascia laterally and cranially to the pubic tubercle in all patients. In 16 patients peritoneal hernial sacs were demonstrated at surgery while in 3 only lipomas (fatty hernia) were contained within the defect. In our opinion DDIH is a specific variety of inguinal hernia with a fairly typical clinical presentation and radiographic appearance but probably often overlooked at surgery.

  14. DIRECT GEOREFERENCING OF UAVS

    Directory of Open Access Journals (Sweden)

    M. Bláha

    2012-09-01

    Full Text Available UAV systems have become an attractive data acquisition platform in emerging applications. As measuring instrument they extend the lineup of possible surveying methods in the field of geomatics. However, most of UAVs are equipped with low-cost navigation sensors such as GPS or INS, allowing a positioning accuracy of 3 to 5 m. As a result the acquired position- and orientation data fea- tures a low accuracy which implicates that it cannot be used in applications that require high precision data on cm-level (e.g. direct georeferencing. In this paper we will analyze the potential of differential post-processing of GPS data from UAV in order to im- prove the positioning accuracy for applications basing on direct georeferencing. Subsequently, the obtained results are compared and verified with a track of the octocopter carried out with a total station simultaneously to the GPS data acquisition. The results show that the differential post-processing essentially improved the accuracy of the Falcon position data. Thereby the average offset be- tween the data sets (GPS data, track and the corresponding standard deviation is 0.82 m and 0.45 m, respectively. However, under ideal conditions it is even possible to improve this positioning accuracy to the cm-range. Furthermore, there are still several sources of error such as the offset between the GPS antenna of the Falcon 8 and the prism which is used for the track. Considering this fact there is further room for improvement regarding the here discussed positioning method.

  15. Direct dark matter detection: The diurnal variation in directional experiments

    CERN Document Server

    Vergados, J D

    2011-01-01

    We present some theoretical results relevant to the direct dark matter detection experiments, paying particular attention to directional experiments, i.e. experiments in which, not only the energy but the direction of the recoiling nucleus is observed. In directional experiments the detection rate depends on the angle between the line observation and the sun's direction of motion. Since, however, the direction of observation is fixed with respect the earth, while the Earth is rotating around its axis, in a directional experiment the angle between the direction of observation and the Sun's direction of motion will change during the day. So the observed signal in such experiments will exhibit a very interesting and characteristic periodic diurnal variation.

  16. Growth directions of microstructures in directional solidification of crystalline materials.

    Science.gov (United States)

    Deschamps, J; Georgelin, M; Pocheau, A

    2008-07-01

    In directional solidification, as the solidification velocity increases, the growth direction of cells or dendrites rotates from the direction of the thermal gradient to that of a preferred cristalline orientation. Meanwhile, their morphology varies with important implications for microsegregation. Here, we experimentally document the growth directions of these microstructures in a succinonitrile alloy in the whole accessible range of directions, velocities, and spacings. For this, we use a thin sample made of a single crystal on which the direction of the thermal gradient can be changed. This allows a fine monitoring of the misorientation angle between thermal gradient and preferred crystalline orientation. Data analysis shows evidence of an internal symmetry which traces back to a scale invariance of growth directions with respect to a Péclet number. This enables the identification of the relationship between growth directions and relevant variables, in fair agreement with experiment. Noticeable variations of growth directions with misorientation angles are evidenced and linked to a single parameter.

  17. Directed animals in the gas

    OpenAIRE

    Borgne, Yvan Le; Marckert, Jean-François

    2006-01-01

    In this paper, we revisit the enumeration of directed animals using gas models. We show that there exists a natural construction of random directed animals on any directed graph together with a particle system that explains at the level of objects the formal link known between the density of the gas model and the generating function of directed animals counted according to the area. This provides some new methods to compute the generating function of directed animals counted according to area...

  18. Directed HK propagator

    Science.gov (United States)

    Kocia, Lucas; Heller, Eric J.

    2015-09-01

    We offer a more formal justification for the successes of our recently communicated "directed Heller-Herman-Kluk-Kay" (DHK) time propagator by examining its performance in one-dimensional bound systems which exhibit at least quasi-periodic motion. DHK is distinguished by its single one-dimensional integral—a vast simplification over the usual 2N-dimensional integral in full Heller-Herman-Kluk-Kay (for an N-dimensional system). We find that DHK accurately captures particular coherent state autocorrelations when its single integral is chosen to lie along these states' fastest growing manifold, as long as it is not perpendicular to their action gradient. Moreover, the larger the action gradient, the better DHK will perform. We numerically examine DHK's accuracy in a one-dimensional quartic oscillator and illustrate that these conditions are frequently satisfied such that the method performs well. This lends some explanation for why DHK frequently seems to work so well and suggests that it may be applicable to systems exhibiting quite strong anharmonicity.

  19. New Directions in Biotechnology

    Science.gov (United States)

    2003-01-01

    The macromolecule crystallization program within NASA is undergoing considerable pressure, particularly budgetary pressure. While it has shown some successes, they have not lived up to the expectations of others, and technological advances may rapidly overtake the natural advantages offered by crystallization in microgravity. Concomitant with the microgravity effort has been a research program to study the macromolecule crystallization process. It was believed that a better understanding of the process would lead to growth of improved crystals for X-ray diffraction studies. The results of the various research efforts have been impressive in improving our understanding of macromolecule crystallization, but have not led to any improved structures. Macromolecule crystallization for structure determination is "one of", the job being unique for every protein and finished once a structure is obtained. However, the knowledge gained is not lost, but instead lays the foundation for developments in new areas of biotechnology and nanotechnology. In this it is highly analogous to studies into small molecule crystallization, the results of which have led to our present day microelectronics-based society. We are conducting preliminary experiments into areas such as designed macromolecule crystals, macromolecule-inorganic hybrid structures, and macromolecule-based nanotechnology. In addition, our protein crystallization studies are now being directed more towards industrial and new approaches to membrane protein crystallization.

  20. Magnetostrictive direct drive motor

    Science.gov (United States)

    Naik, Dipak; Dehoff, P. H.

    1991-01-01

    Highly magnetostrictive materials such as Tb.3Dy.7Fe2, commercially known as TERFENOL-D, have been used to date in a variety of devices such as high power actuators and linear motors. The larger magnetostriction available in twinned single crystal TERFENOL-D, approx. 2000 ppm at moderate magnetic field strengths, makes possible a new generation of magnetomechanical devices. NASA researchers are studying the potential of this material as the basis for a direct microstepping rotary motor with torque densities on the order of industrial hydraulics and five times greater than that of the most efficient, high power electric motors. Such a motor would be a micro-radian stepper, capable of precision movements and self-braking in the power-off state. Innovative mechanical engineering techniques are juxtaposed on proper magnetic circuit design to reduce losses in structural flexures, inertias, thermal expansions, eddy currents, and magneto-mechanical coupling, thus optimizing motor performance and efficiency. Mathematical models are presented, including magnetic, structural, and both linear and nonlinear dynamic calculations and simulations. In addition, test results on prototypes are presented.

  1. Directed Incremental Symbolic Execution

    Science.gov (United States)

    Person, Suzette; Yang, Guowei; Rungta, Neha; Khurshid, Sarfraz

    2011-01-01

    The last few years have seen a resurgence of interest in the use of symbolic execution -- a program analysis technique developed more than three decades ago to analyze program execution paths. Scaling symbolic execution and other path-sensitive analysis techniques to large systems remains challenging despite recent algorithmic and technological advances. An alternative to solving the problem of scalability is to reduce the scope of the analysis. One approach that is widely studied in the context of regression analysis is to analyze the differences between two related program versions. While such an approach is intuitive in theory, finding efficient and precise ways to identify program differences, and characterize their effects on how the program executes has proved challenging in practice. In this paper, we present Directed Incremental Symbolic Execution (DiSE), a novel technique for detecting and characterizing the effects of program changes. The novelty of DiSE is to combine the efficiencies of static analysis techniques to compute program difference information with the precision of symbolic execution to explore program execution paths and generate path conditions affected by the differences. DiSE is a complementary technique to other reduction or bounding techniques developed to improve symbolic execution. Furthermore, DiSE does not require analysis results to be carried forward as the software evolves -- only the source code for two related program versions is required. A case-study of our implementation of DiSE illustrates its effectiveness at detecting and characterizing the effects of program changes.

  2. Coatings for directional eutectics

    Science.gov (United States)

    Rairden, J. R.; Jackson, M. R.

    1976-01-01

    Coatings developed to provide oxidation protection for the directionally-solidified eutectic alloy NiTaC-B (4.4 weight percent Cr) were evaluated. Of seven Co-, Fe- and Ni-base coatings that were initially investigated, best resistance to cyclic oxidation was demonstrated by duplex coatings fabricated by depositing a layer of NiCrAl(Y) by vacuum evaporation from an electron beam source followed by deposition of an Al overlayer using the pack cementation process. It was found that addition of carbon to the coating alloy substantially eliminated the problem of fiber denudation in TaC-type eutectic alloys. Burner rig cycled NiTaC-B samples coated with Ni-20Cr-5Al-0.1C-0.1Y+Al and rupture-tested at 1100 deg C performed as well as or better than uncoated, vacuum cycled and air-tested NiTaC-13; however, a slight degradation with respect to uncoated material was noted in air-stress rupture tests at 870 deg C for both cycled and uncycled samples.

  3. Directionally solidified mullite fibers

    Energy Technology Data Exchange (ETDEWEB)

    Sayir, A. [Case Western Reserve Univ., Cleveland, OH (United States); Farmer, S.C. [National Aeronautics and Space Administration, Cleveland, OH (United States). Lewis Research Center

    1995-10-01

    Directionally solidified fibers with nominal mullite compositions of 3Al{sub 2}O{sub 3} {center_dot} 2SiO{sub 2} were grown by the laser heated float zone (LHFZ) method at NASA Lewis. High resolution digital images from an optical microscope evidence the formation of a liquid-liquid miscibility gap during crystal growth. Experimental evidence shows that the formation of mullite in aluminosilicate melts is in fact preceded by liquid immiscibility. The average fiber tensile strength is 1.15 GPa at room temperature. The mullite fibers retained 80% of their room temperature tensile strength at 1,450 C. SEM analysis revealed that the fibers were strongly faceted and that the facets act as critical flaws. Examined in TEM, these mullite single crystals are free of dislocations, low angle boundaries and voids. Single crystal mullite showed a high degree of oxygen vacancy ordering. Regardless of the starting composition, the degree of order observed in polycrystalline fibers was lower than that observed in the mullite single crystals.

  4. The median recoil direction as a WIMP directional detection signal

    OpenAIRE

    Green, Anne M; MORGAN, BEN

    2010-01-01

    Direct detection experiments have reached the sensitivity required to detect dark matter WIMPs. Demonstrating that a putative signal is due to WIMPs, and not backgrounds, is a major challenge however. The direction dependence of the WIMP scattering rate provides a potential WIMP `smoking gun'. If the WIMP distribution is predominantly smooth, the Galactic recoil distribution is peaked in the direction opposite to the direction of Solar motion. Previous studies have found that, for an ideal de...

  5. Directed and Almost-Directed Flow Loops in Real Networks

    Directory of Open Access Journals (Sweden)

    M. Todinov

    2013-09-01

    Full Text Available Directed flow loops are highly undesirable because they are associated with wastage of energy for maintaining them and entail big losses to the world economy. It is shown that directed flow loops may appear in networks even if the dispatched commodity does not physically travel along a closed contour. Consequently, a theorem giving the necessary and sufficient condition of a directed flow loop on randomly oriented straight-line flow paths has been formulated and a close-form expression has been derived for the probability of a directed flow loop. The results show that even for a relatively small number of intersecting flow paths, the probability of a directed flow loop is very large, which means that the existence of directed flow loops in real networks is practically inevitable. Consequently, a theorem and an efficient algorithm have been proposed related to discovering and removing directed flow loops in a network with feasible flows. The new concept ‘almost-directed flow loop’ has also been introduced for the first time. It is shown that the removal of an almost-directed flow loop also results in a significant decrease of the losses. It is also shown that if no directed flow loops exist in the network, the removal of an almost-directed flow loop cannot create a directed flow loop.

  6. Efficient multi-site-directed mutagenesis directly from genomic template

    Indian Academy of Sciences (India)

    Fengtao Luo; Xiaolan Du; Tujun Weng; Xuan Wen; Junlan Huang; Lin Chen

    2012-12-01

    In this article, the traditional multi-site-directed mutagenesis method based on overlap extension PCR was improved specifically for complicated templates, such as genomic sequence or complementary DNA. This method was effectively applied for multi-site-directed mutagenesis directly from mouse genomic DNA, as well as for combination, deletion or insertion of DNA fragments.

  7. Future directions of MDSplus

    Energy Technology Data Exchange (ETDEWEB)

    Manduchi, G., E-mail: gabriele.manduchi@igi.cnr.it [Consorzio RFX, Corso Stati Uniti 4, 35127 Padova (Italy); Fredian, T., E-mail: twf@psfc.mit.edu [Massachusetts Institute of Technology, 175 Albany Street, Cambridge, MA 02139 (United States); Stillerman, J., E-mail: jas@psfc.mit.edu [Massachusetts Institute of Technology, 175 Albany Street, Cambridge, MA 02139 (United States)

    2014-05-15

    Highlights: • This paper describes the directions in the evolution of the MDSplus data system. • It describes three Use Cases in data streaming. • It shows the performance of MDSplus in local and remote data streaming. • It describes the main concepts in decoupling data access. • It presents the last features and tools. - Abstract: The first version of MDSplus was released in 1991 for VAX/VMS. Since then MDSplus has been progressively adopted in an increasing number of fusion experiments and its original implementation has been extended during these years to cover new requirements and toward a multi-platform implementation. Currently MDSplus is in use at more than 30 laboratories and is being used both for pulsed applications as well as for continuous data streaming for long lasting experiments. Thanks to its large user base, it has been possible to collect requirements driving the evolution of the system toward improved usability and better performance. An important recent feature of the MDSplus is its ability of handling a continuous stream of data, which is readily available as soon at it has been stored in the pulse files. Current development is oriented toward an improved modularity of MDSplus and the integration of new functionality. Improved modularity is achieved by moving away from monolithic implementation toward a plug-ins approach. This has already been achieved recently for the management of remote data access, where the original TCP/IP implementation can now be integrated with new user-provided network protocols. Following a similar approach, work is in progress to let new back-ends be integrated in the MDSplus data access layer. By decoupling the MDSplus data management from the disk data file format it is possible to integrate new solutions such as data cloud without affecting the user Application Programming Interface.

  8. Annual national direct and indirect cost estimates of the prevention and treatment of cervical cancer in Brazil

    Science.gov (United States)

    Novaes, Hillegonda Maria Dutilh; Itria, Alexander; Silva, Gulnar Azevedo e; Sartori, Ana Marli Christovam; Rama, Cristina Helena; de Soárez, Patrícia Coelho

    2015-01-01

    OBJECTIVE: To estimate the annual direct and indirect costs of the prevention and treatment of cervical cancer in Brazil. METHODS: This cost description study used a "gross-costing" methodology and adopted the health system and societal perspectives. The estimates were grouped into sets of procedures performed in phases of cervical cancer care: the screening, diagnosis and treatment of precancerous lesions and the treatment of cervical cancer. The costs were estimated for the public and private health systems, using data from national health information systems, population surveys, and literature reviews. The cost estimates are presented in 2006 USD. RESULTS: From the societal perspective, the estimated total costs of the prevention and treatment of cervical cancer amounted to USD $1,321,683,034, which was categorized as follows: procedures (USD $213,199,490), visits (USD $325,509,842), transportation (USD $106,521,537) and productivity losses (USD $676,452,166). Indirect costs represented 51% of the total costs, followed by direct medical costs (visits and procedures) at 41% and direct non-medical costs (transportation) at 8%. The public system represented 46% of the total costs, and the private system represented 54%. CONCLUSION: Our national cost estimates of cervical cancer prevention and treatment, indicating the economic importance of cervical cancer screening and care, will be useful in monitoring the effect of the HPV vaccine introduction and are of interest in research and health care management. PMID:26017797

  9. New air quality guidelines: framework directive and daughter directive

    Directory of Open Access Journals (Sweden)

    Rosalía Fernández Patier

    2002-12-01

    Full Text Available The old Directives about air quality had some problems in their application, both in the management of ambient air quality and in the lack of public information. The new Directives, based in 96/62/EC Directive about assesment and management of ambient air resolve these problems. They are more strict in permited limit values of pollutants and establish new Directives for new pollutants. The new Directives have been transposed the national legislation in RD 1073/2002 of 18 October.

  10. Directional wave measurements and modelling

    Digital Repository Service at National Institute of Oceanography (India)

    Anand, N.M.; Nayak, B.U.; Bhat, S.S.; SanilKumar, V.

    Some of the results obtained from analysis of the monsoon directional wave data measured over 4 years in shallow waters off the west coast of India are presented. The directional spectrum computed from the time series data seems to indicate...

  11. Estimation of directional wave spreading

    Digital Repository Service at National Institute of Oceanography (India)

    Mandal, S.; Bhat, S.S.; Anand, N.M.; Nayak, B.U.

    Directional properties of ocean waves are of great economic interest. The knowledge of wave directionality is important for the design of maritime structures and offshore operations. Two main aspects are considered for this study for the data...

  12. Forman curvature for directed networks

    CERN Document Server

    Sreejith, R P; Saucan, Emil; Samal, Areejit

    2016-01-01

    A goal in network science is the geometrical characterization of complex networks. In this direction, we have recently introduced the Forman's discretization of Ricci curvature to the realm of undirected networks. Investigation of Forman curvature in diverse model and real-world undirected networks revealed that this measure captures several aspects of the organization of complex undirected networks. However, many important real-world networks are inherently directed in nature, and the Forman curvature for undirected networks is unsuitable for analysis of such directed networks. Hence, we here extend the Forman curvature for undirected networks to the case of directed networks. The simple mathematical formula for the Forman curvature in directed networks elegantly incorporates node weights, edge weights and edge direction. By applying the Forman curvature for directed networks to a variety of model and real-world directed networks, we show that the measure can be used to characterize the structure of complex ...

  13. BOREL'S DIRECTIONS AND SHARED VALUES

    Institute of Scientific and Technical Information of China (English)

    Qingcai ZHANG

    2013-01-01

    In this article,we study the problems of Borel's directions of meromorphic functions concerning shared values and prove that if two meromorphic functions of infinite order share three distinct values,their Borel's directions are same.

  14. Innovative tool of direct marketing

    Directory of Open Access Journals (Sweden)

    T.S. Maksymova

    2010-06-01

    Full Text Available The aspects of direct marketing activation on the basis of interactive applications introduction are examined. Basic advantages, linked with the use of the integrated marketing communications during formation of direct marketing strategies are open up.

  15. Estimation of wave directional spreading

    Digital Repository Service at National Institute of Oceanography (India)

    Deo, M.C.; Gondane, D.S.; SanilKumar, V.

    One of the useful measures of waves directional spreading at a given location is the directional spreading parameter. This paper presents a new approach to arrive at its characteristic value using the computational technique of Artificial Neural...

  16. A Change of Direction

    Science.gov (United States)

    2004-01-01

    [figure removed for brevity, see original site] Released July 21, 2004 The atmosphere of Mars is a dynamic system. Water-ice clouds, fog, and hazes can make imaging the surface from space difficult. Dust storms can grow from local disturbances to global sizes, through which imaging is impossible. Seasonal temperature changes are the usual drivers in cloud and dust storm development and growth. Eons of atmospheric dust storm activity has left its mark on the surface of Mars. Dust carried aloft by the wind has settled out on every available surface; sand dunes have been created and moved by centuries of wind; and the effect of continual sand-blasting has modified many regions of Mars, creating yardangs and other unusual surface forms. In this image we can clearly see a major change in wind regimes. The classic yardang form occupies the top of the image. These older yardangs were formed by a NW/SE wind regime. The younger, smaller yardangs are forming in the rest of the image from a NE/SW wind. The age relationship is readily visible at the intersection area, where the large yardangs are being cut crosswise into NE/SW aligned forms. The top framelet of this image has vertical black/white lines caused by charge on the camera CCD. Image information: VIS instrument. Latitude -6.3, Longitude 183.8 East (176.2 West). 19 meter/pixel resolution. Note: this THEMIS visual image has not been radiometrically nor geometrically calibrated for this preliminary release. An empirical correction has been performed to remove instrumental effects. A linear shift has been applied in the cross-track and down-track direction to approximate spacecraft and planetary motion. Fully calibrated and geometrically projected images will be released through the Planetary Data System in accordance with Project policies at a later time. NASA's Jet Propulsion Laboratory manages the 2001 Mars Odyssey mission for NASA's Office of Space Science, Washington, D.C. The Thermal Emission Imaging System (THEMIS

  17. New directions at NSF

    Science.gov (United States)

    Harvey, Albert B.

    1995-10-01

    The mission and scope of the National Science Foundation (NSF) and lightwave technology will be very briefly discussed. The focus of the presentation will be directed toward changes in research support that are taking place and the opportunities we have for aiming our research to meet the challenges and needs that face the nation. In the USA it is very clear that defense oriented research is downsizing and is being redirected into economy driven aresas, such as manufacturing, business, and industry. For those researchers who are willing to move into these areas and find a niche, the rewards may be very great. Industrial research partners should also seize these opportunities to enhance their resources in an otherwise bleak future for industrial support of basic research in lightwave technology and many other reserach disciplines. These activities of bringing together industry and academia will have the value added benefit of providing increased job opportunities for students. An outline of some of these opportunities and incentives will be presented. On the international front, there has never been a better time for the encouragement of joint research and collaboration across borders. The economic potential for involvement in Eastern Europe and Asia are enormous. Agencies like ourselves are open to help support of visiting scientist/engineer exchange, international conferences and forums and support of innovative ideas to help further enhance economic developemnt of the world and hence the quality of life. The presence of the Russian delegation here at these SPIE meetings in in part the result of NSF support. Concomitant with these changes is a growing interest in education. Academia is gradually realizing that education includes training for students to acquire jobs and hence we complete the cycle of the importance of interacting with industry. At the NSF a major new initiative is being introduced in Optical Science and Engineering (OSE). This effort has been

  18. Edge adaptive directional total variation

    Directory of Open Access Journals (Sweden)

    Hua Zhang

    2013-11-01

    Full Text Available The directional total variation (DTV model has been proposed very recently for image denoising. However, the DTV model works well when there is just one dominant direction in the image. In this Letter, the authors propose to make the DTV model adaptive to image edge direction so that the proposed model can handle images with several dominant directions. Experiment and comparison show the effectiveness of the proposed method.

  19. Optimal selection for direct mail

    NARCIS (Netherlands)

    Bult, [No Value; Wansbeek, T

    1995-01-01

    Direct marketing (mail) is a growing area of marketing practice, yet the academic journals contain very little research on this topic. The most important issue for direct marketers is how to sample targets from a population for a direct mail campaign. Although some selection methods are described in

  20. Optimal selection for direct mail

    NARCIS (Netherlands)

    Bult, [No Value; Wansbeek, T

    1995-01-01

    Direct marketing (mail) is a growing area of marketing practice, yet the academic journals contain very little research on this topic. The most important issue for direct marketers is how to sample targets from a population for a direct mail campaign. Although some selection methods are described in

  1. Motor directional tuning across brain areas: Directional resonance and the role of inhibition for directional accuracy

    Directory of Open Access Journals (Sweden)

    Margaret Yvonne Mahan

    2013-05-01

    Full Text Available Motor directional tuning (Georgopoulos et al., 1982 has been found in every brain area in which it has been sought for during the past 30-odd years. It is typically broad, with widely distributed preferred directions and a population signal that predicts accurately the direction of an upcoming reaching movement or isometric force pulse (Georgopoulos et al., 1992. What is the basis for such ubiquitous directional tuning? How does the tuning come about? What are the implications of directional tuning for understanding the brain mechanisms of movement in space? This review addresses these questions in the light of accumulated knowledge in various sub-fields of neuroscience and motor behavior. It is argued (a that direction in space encompasses many aspects, from vision to muscles, (b that there is a directional congruence among the central representations of these distributed directions arising from rough but orderly topographic connectivities among brain areas, (c that broad directional tuning is the result of broad excitation limited by recurrent and non-recurrent (i.e. direct inhibition within the preferred direction loci in brain areas, and (d that the width of the directional tuning curve, modulated by local inhibitory mechanisms, is a parameter that determines the accuracy of the directional command.

  2. Multi-Directional Motion Adaptation

    Directory of Open Access Journals (Sweden)

    David Patrick McGovern

    2012-05-01

    Full Text Available The direction aftereffect (DAE is a phenomenon whereby prolonged exposure to a moving stimulus biases the perceived direction of subsequent stimuli. It is believed to arise through a selective suppression of directionally tuned neurons in the visual cortex, causing shifts in the population response away from the adapted direction. Whereas most studies consider only unidirectional adaptation, here we examine how concurrent adaptation to multiple directions affects the DAE. Observers were required to judge whether a random dot kinematogram (RDK moved clockwise or counter-clockwise relative to upwards. In different conditions, observers adapted to a stimulus comprised of directions drawn from a distribution or to bidirectional motion. Increasing the variance of normally distributed directions reduced the magnitude of the peak DAE and broadened its tuning profile. Asymmetric sampling of Gaussian and uniform distributions resulted in shifts of DAE tuning profiles consistent with changes in the perceived global direction of the adapting stimulus. Discrimination thresholds were elevated by an amount that related to the magnitude of the bias. For bidirectional adaptors, adding dots in directions away from the adapting motion led to a pronounced reduction in the DAE. This reduction was observed when dots were added in opposite or orthogonal directions to the adaptor suggesting that it may arise via inhibition from a broadly tuned normalisation pool. Preliminary simulations with a population coding model, where the gain of a direction-selective neuron is inversely proportional to its response to the adapting stimulus, suggest that it provides a parsimonious account of these adaptation effects.

  3. Donor Conception Disclosure: Directive or Non-Directive Counselling?

    Science.gov (United States)

    Raes, Inez; Ravelingien, An; Pennings, Guido

    2016-09-01

    It is widely agreed among health professionals that couples using donor insemination should be offered counselling on the topic of donor conception disclosure. However, it is clear from the literature that there has long been a lack of agreement about which counselling approach should be used in this case: a directive or a non-directive approach. In this paper we investigate which approach is ethically justifiable by balancing the two underlying principles of autonomy (non-directive approach) and beneficence (directive approach). To overrule one principle in favour of another, six conditions should be fulfilled. We analyse the arguments in favour of the beneficence principle, and consequently, a directive approach. This analysis shows that two conditions are not met; the principle of autonomy should not be overridden. Therefore, at this moment, a directive counselling approach on donor conception disclosure cannot be ethically justified.

  4. The median recoil direction as a WIMP directional detection signal

    CERN Document Server

    Green, Anne M

    2010-01-01

    Direct detection experiments have reached the sensitivity required to detect dark matter WIMPs. Demonstrating that a putative signal is due to WIMPs, and not backgrounds, is a major challenge however. The direction dependence of the WIMP scattering rate provides a potential WIMP `smoking gun'. If the WIMP distribution is predominantly smooth, the Galactic recoil distribution is peaked in the direction opposite to the direction of Solar motion. Previous studies have found that, for an ideal detector, of order 10 WIMP events would be sufficient to reject isotropy, and rule out an isotropic background. We examine how the median recoil direction could be used to confirm the WIMP origin of an anisotropic recoil signal. Specifically we determine the number of events required to reject the null hypothesis that the median direction is random (corresponding to an isotropic Galactic recoil distribution) at 95% confidence. We find that for zero background 31 events are required, a factor of roughly 2 more than are requi...

  5. A search for direct muon production in the forward direction

    Energy Technology Data Exchange (ETDEWEB)

    Buchholz, D.; /Caltech; Johnson, Rolland P.; /Fermilab; Sumner, R.L.; /Princeton U.; Fackler, O.; /Rockefeller U.; Frisch, Henry J.; Shochet, M.; /Chicago U.

    1974-01-01

    We propose to search for direct muon production in the forward direction from 300 GeV protons incident on a heavy nuclear target. By using the first stage of the Ml beam as a source of a diffracted proton beam and the second and third stages of Ml as a spectrometer, one can make a measurement of the direct muon to pion ratio at values of x between 0.3 and 0.75. If this ratio is on the order of 10{sup -4}, the event rates are on the order of 800 direct muons/hr. at an x of .5. The modifications to the Ml beam are minor.

  6. 78 FR 32533 - Proposed Collection of Information: Direct Deposit, Go Direct, and Direct Express Sign-Up Forms

    Science.gov (United States)

    2013-05-30

    ... Bureau of the Fiscal Service Proposed Collection of Information: Direct Deposit, Go Direct, and Direct...'', Form 1200 ``Go Direct Sign-Up Form for Direct Deposit of Federal Benefit Payments'', Form 1200VADE... below: Title: Direct Deposit Sign-Up Form, and Go Direct Sign-Up Form, and Direct Express Form for...

  7. Directionality Time - New Analytical Treatment of Directionally Biased, Crawling Motility

    Science.gov (United States)

    Tang, Jay; Loosley, Alexander

    Insights on crucial biological functions often emerge from measuring how animal cells crawl on surfaces, particularly in response to gradients of external cues that cause directionally biased motion. Most existing metrics commonly used to characterize directional migration, such as straightness index (or chemotactic index), persistence time, and turning angle distribution, tend to be sensitive to relatively large errors at short sampling times. In contrast, we recently introduced a new metric, called directionality time, to define the onset time by which a seemingly random motion becomes directionally biased (O'Brien et al., J Leukocyte Biol, 2014, 95:993-1004 Loosley et al., PLOS ONE, 2015, 10.1371). Directionality time is obtained by fitting the mean squared displacement as a function of time interval, in log-log coordinates, to a fit function based on biased and persistent random walk processes. We show that the fit function is approximately model invariant and is applicable to a variety of directionally biased motions. Simulations are performed to show the robustness of the directionality time model and its decoupling from measurement errors. Finally, we demonstrate as an example how to usefully apply the directionality time fit to trajectories of chemotactic neutrophils.

  8. Direct cooled power electronics substrate

    Science.gov (United States)

    Wiles, Randy H [Powell, TN; Wereszczak, Andrew A [Oak Ridge, TN; Ayers, Curtis W [Kingston, TN; Lowe, Kirk T [Knoxville, TN

    2010-09-14

    The disclosure describes directly cooling a three-dimensional, direct metallization (DM) layer in a power electronics device. To enable sufficient cooling, coolant flow channels are formed within the ceramic substrate. The direct metallization layer (typically copper) may be bonded to the ceramic substrate, and semiconductor chips (such as IGBT and diodes) may be soldered or sintered onto the direct metallization layer to form a power electronics module. Multiple modules may be attached to cooling headers that provide in-flow and out-flow of coolant through the channels in the ceramic substrate. The modules and cooling header assembly are preferably sized to fit inside the core of a toroidal shaped capacitor.

  9. Advance directives: prerequisites and usefulness.

    Science.gov (United States)

    van Asselt, D

    2006-10-01

    Advance directives allow competent persons to extend their right of self-determination into the future, by recording choices that are intended to influence their future care should they become unable to make choices. They are considered tools to facilitate end-of-life decision making. Advance directives are a form of anticipatory decision-making. This article will focus on instruction directives against a certain treatment, so-called advance refusals. The most important legal requirement is the acknowledgement of patient autonomy. This condition is met in all European countries. The legal uncertainties surrounding advance refusals are focused on practical modalities rather than on the validity of the general principle. According to leading ethics the underlying moral rule of advanced directives is that all truly autonomous refusals of treatment must be respected, no matter what the consequences. Physicians find it hard to adhere to the wishes and choices of patients as expressed in directives. They find the text ambiguous. Another weakness is that directives give little information about what in the patient's view constitutes a good quality of life. Some health professionals lack the willingness to step outside their own value systems and fully embrace that of the patient. Empathic skills are required. Very few persons create an advance directive. Furthermore, of the created directives only some are accessible when patients are admitted to hospital. However, when directives are available they usually influence medical treatment decisions.

  10. New directions in information organization

    CERN Document Server

    Park, Jung-ran; Spink, Amanda

    2013-01-01

    New Directions in Information Organization, co-edited by Dr. Jung-ran Park and Dr. Lynne Howarth seeks to provide an overview and understanding of the future directions, leading edge theories and models for research and practice in information organization.

  11. Strategic directions in tissue engineering.

    NARCIS (Netherlands)

    Johnson, P.C.; Mikos, A.G.; Fisher, J.P.; Jansen, J.A.

    2007-01-01

    The field of tissue engineering is developing rapidly. Given its ultimate importance to clinical care, the time is appropriate to assess the field's strategic directions to optimize research and development activities. To characterize strategic directions in tissue engineering, a distant but reachab

  12. Type-Directed Partial Evaluation

    DEFF Research Database (Denmark)

    Danvy, Olivier

    1998-01-01

    Type-directed partial evaluation uses a normalization function to achieve partial evaluation. These lecture notes review its background, foundations, practice, and applications. Of specific interest is the modular technique of offline and online type-directed partial evaluation in Standard ML...

  13. Type-Directed Partial Evaluation

    DEFF Research Database (Denmark)

    Danvy, Olivier

    1998-01-01

    Type-directed partial evaluation uses a normalization function to achieve partial evaluation. These lecture notes review its background, foundations, practice, and applications. Of specific interest is the modular technique of offline and online type-directed partial evaluation in Standard ML of ...

  14. Efficient Placement of Directional Antennas

    Energy Technology Data Exchange (ETDEWEB)

    Pan, Feng [Los Alamos National Laboratory; Kasiviswanathan, Shiva [Los Alamos National Laboratory

    2010-09-20

    Directional antenna is an technology for the proliferation of wireless networks. In centralized wireless network, wireless devices communicate through base stations. Directed antennas are placed on base stations and form a backbone of communication. The communication between base stations and wireless devices can be interfered due to a large number of wireless device. Methodically positioning and orienting directed antennas can help to reduce the interference while saving energy. An integer linear programming is developed for siting and directing antennas on multiple base stations, and this formulation can be extended to model non-overlapping channels. Through the integer programming formulation, optimal antenna positions can be used to analyze the performance of directed antennas with different parameters like the number base stations and the number of non-overlapping channels.

  15. Chapter 1: Direct Normal Radiation

    Energy Technology Data Exchange (ETDEWEB)

    Myer, Daryl R.

    2016-04-15

    This chapter addresses the quantitative and qualitative aspects of the solar resource, the direct solar radiation. It discusses the total or integrated broadband direct beam extraterrestrial radiation (ETR). This total integrated irradiance is comprised of photons of electromagnetic radiation. The chapter also discusses the impact of the atmosphere and its effect upon the direct normal irradiance (DNI) beam radiation. The gases and particulates present in the atmosphere traversed by the direct beam reflect, absorb, and scatter differing spectral regions and proportions of the direct beam, and act as a variable filter. Knowledge of the available broadband DNI beam radiation resource data is essential in designing a concentrating photovoltaic (CPV) system. Spectral variations in the DNI beam radiation affect the performance of a CPV system depending on the solar cell technology used. The chapter describes propagation and scattering processes of circumsolar radiation (CSR), which includes the Mie scattering from large particles.

  16. Single Image Superresolution via Directional Group Sparsity and Directional Features.

    Science.gov (United States)

    Li, Xiaoyan; He, Hongjie; Wang, Ruxin; Tao, Dacheng

    2015-09-01

    Single image superresolution (SR) aims to construct a high-resolution version from a single low-resolution (LR) image. The SR reconstruction is challenging because of the missing details in the given LR image. Thus, it is critical to explore and exploit effective prior knowledge for boosting the reconstruction performance. In this paper, we propose a novel SR method by exploiting both the directional group sparsity of the image gradients and the directional features in similarity weight estimation. The proposed SR approach is based on two observations: 1) most of the sharp edges are oriented in a limited number of directions and 2) an image pixel can be estimated by the weighted averaging of its neighbors. In consideration of these observations, we apply the curvelet transform to extract directional features which are then used for region selection and weight estimation. A combined total variation regularizer is presented which assumes that the gradients in natural images have a straightforward group sparsity structure. In addition, a directional nonlocal means regularization term takes pixel values and directional information into account to suppress unwanted artifacts. By assembling the designed regularization terms, we solve the SR problem of an energy function with minimal reconstruction error by applying a framework of templates for first-order conic solvers. The thorough quantitative and qualitative results in terms of peak signal-to-noise ratio, structural similarity, information fidelity criterion, and preference matrix demonstrate that the proposed approach achieves higher quality SR reconstruction than the state-of-the-art algorithms.

  17. Potential Theory for Directed Networks

    Science.gov (United States)

    Zhang, Qian-Ming; Lü, Linyuan; Wang, Wen-Qiang; Zhou, Tao

    2013-01-01

    Uncovering factors underlying the network formation is a long-standing challenge for data mining and network analysis. In particular, the microscopic organizing principles of directed networks are less understood than those of undirected networks. This article proposes a hypothesis named potential theory, which assumes that every directed link corresponds to a decrease of a unit potential and subgraphs with definable potential values for all nodes are preferred. Combining the potential theory with the clustering and homophily mechanisms, it is deduced that the Bi-fan structure consisting of 4 nodes and 4 directed links is the most favored local structure in directed networks. Our hypothesis receives strongly positive supports from extensive experiments on 15 directed networks drawn from disparate fields, as indicated by the most accurate and robust performance of Bi-fan predictor within the link prediction framework. In summary, our main contribution is twofold: (i) We propose a new mechanism for the local organization of directed networks; (ii) We design the corresponding link prediction algorithm, which can not only testify our hypothesis, but also find out direct applications in missing link prediction and friendship recommendation. PMID:23408979

  18. Direct optical to microwave conversion

    Science.gov (United States)

    Taylor, Henry F.

    1990-09-01

    Support of high frequency fiber optic links through development of innovative higher efficiency techniques to convert optical energy directly to RF Energy. Control of Phases Arrays by optical means in an area of expanding technology development. Fiber optics and other forms of optical waveguide can provide greater accuracy and true time delay in a phase delay network. Methods of improvement in transfer of optical energy to RF Energy are determined. Development of Direct Optical-to-RF-Direct Amplifiers will result in higher efficiency, low noise, optical receivers for fiber optic links with improved performance. This results in longer fiber optic links without repeaters and improved BER or shorter links.

  19. Module bay with directed flow

    Science.gov (United States)

    Torczynski, John R.

    2001-02-27

    A module bay requires less cleanroom airflow. A shaped gas inlet passage can allow cleanroom air into the module bay with flow velocity preferentially directed toward contaminant rich portions of a processing module in the module bay. Preferential gas flow direction can more efficiently purge contaminants from appropriate portions of the module bay, allowing a reduced cleanroom air flow rate for contaminant removal. A shelf extending from an air inlet slit in one wall of a module bay can direct air flowing therethrough toward contaminant-rich portions of the module bay, such as a junction between a lid and base of a processing module.

  20. Prisoner's dilemma on directed networks

    CERN Document Server

    Ferreira, A L; Pedro, T B; Santos, M; Figueiredo, W

    2016-01-01

    We study the prisoner's dilemma model with a noisy imitation evolutionary dynamics on directed out-homogeneous and uncorrelated directed random networks. An heterogeneous pair mean-field approximation is presented showing good agreement with Monte Carlo simulations in the limit of weak selection (high noise) where we obtain analytical predictions for the critical temptations. We discuss the phase diagram as a function of temptation, intensity of noise and coordination number of the networks and we consider both the model with and without self-interaction. We compare our results with available results for non-directed lattices and networks.

  1. Directional spectrum of ocean waves

    Digital Repository Service at National Institute of Oceanography (India)

    Fernandes, A.A.; Gouveia, A.D.; Nagarajan, R.

    fields are described. For these sinusoidal wave fields, analysis of both linear and polygonal arrays consistently yielded accurate directions, in contrast with the limited success of Pawka (1974) in case of linear arrays and Esteva (1976, 1977) in case...

  2. EOP Current Magnitude and Direction

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data contain shipboard current magnitudes and directions collected in the Pacific, both pelagic and near shore environments. Data is collected using an RD...

  3. Directional irradiances and fractional clouds

    Science.gov (United States)

    Pagh Nielsen, Kristian; Andersen, Elsa; Dragsted, Janne; Furbo, Simon

    2017-04-01

    For large scale implementation of solar energy, better understanding of the directional and temporal variations in the solar resource is needed. This includes understanding the shading within a multiple row field of solar panels and how this affects the electricity or heat production. We have studied directional irradiances measured simultaneously from 16 downward directions at 1 minute temporal resolution. Also, we have performed measurements of the variations in the field of view across individual solar heating panels in the operational solar district heating plant in Hedehusene in Denmark. By combining a model of directional diffuse irradiances with the field of view variation across a solar panel in a solar panel field we can quantify the effect of shading of diffuse irradiances on the heat flow from the panel.

  4. Multi-Directional Experimental Facility

    Data.gov (United States)

    Federal Laboratory Consortium — The ATLSS Multi-directional Experimental Laboratory was constructed in 1987 under funding from the National Science Foundation to be a major facility for large-scale...

  5. Directed Innovation of Business Models

    Directory of Open Access Journals (Sweden)

    Stelian Brad

    2016-06-01

    Full Text Available Business model innovation is an important issue to keep business competitive and increase company’s profits. Due to many market attractors, identification of appropriate paths of business model evolution is a painful and risky process. To improve decision’s effectiveness in this process, an architectural construct of analysis and conceptualization for business model innovation that combines directed evolution and blue ocean concepts is proposed in this paper under the name of directed innovation. It displays the key points where innovations would happen to direct adaptation of the business model towards sustainable competitiveness. Formulation of mature solutions is supported by inventive problem solving tools. The significance of the directed innovation approach is demonstrated in a case study dealing with business model innovation of a software company.

  6. Direct Broadcast Satellite: Radio Program

    Science.gov (United States)

    Hollansworth, James E.

    1992-01-01

    NASA is committed to providing technology development that leads to the introduction of new commercial applications for communications satellites. The Direct Broadcast Satellite-Radio (DBS-R) Program is a joint effort between The National Aeronautics and Space Administration (NASA) and The United States Information Agency/Voice of America (USIA/VOA) directed at this objective. The purpose of this program is to define the service and develop the technology for a direct-to-listener satellite sound broadcasting system. The DBS-R Program, as structured by NASA and VOA, is now a three-phase program designed to help the U.S. commercial communications satellite and receiver industry bring about this new communications service. Major efforts are being directed towards frequency planning hardware and service development, service demonstration, and experimentation with new satellite and receiver technology.

  7. Major Directions in Creativity Research.

    Science.gov (United States)

    Khatena, Joe

    Reviewed are major directions in creativity research in the following areas: theories of creativity; definitions; instruments to measure creativity; nurturing creativity; the disabled, disturbed, and disadvantaged; cross cultural patterns; creative imagination imagery; and measuring creative imagination imagery. (LS)

  8. Photon upconversion with directed emission

    Science.gov (United States)

    Börjesson, K.; Rudquist, P.; Gray, V.; Moth-Poulsen, K.

    2016-08-01

    Photon upconversion has the potential to increase the efficiency of single bandgap solar cells beyond the Shockley Queisser limit. Efficient light management is an important point in this context. Here we demonstrate that the direction of upconverted emission can be controlled in a reversible way, by embedding anthracene derivatives together with palladium porphyrin in a liquid crystalline matrix. The system is employed in a triplet-triplet annihilation photon upconversion scheme demonstrating controlled switching of directional anti Stokes emission. Using this approach an emission ratio of 0.37 between the axial and longitudinal emission directions and a directivity of 1.52 is achieved, reasonably close to the theoretical maximal value of 2 obtained from a perfectly oriented sample. The system can be switched for multiple cycles without any visible degradation and the speed of switching is only limited by the intrinsic rate of alignment of the liquid crystalline matrix.

  9. Cyber Enabled Direct Digital Manufacturing

    Science.gov (United States)

    2015-05-15

    3 - A survey of sensing and control systems for machine and process monitoring of directed energy, metal-based additive manufacturing A3-1 Appendix...Street Journal, p. B2, 7 February 2013. [4] National Center for Defense Manufacturing and Machining , "National Additive Manufacturing Innovation...and control systems for machine and process monitoring of directed energy, metal-based additive manufacturing Reutzel, E.W., Nassar, A.R., 2015. A

  10. Spillovers from Foreign Direct Investment

    DEFF Research Database (Denmark)

    Meyer, Klaus E.; Sinani, Evis

    2005-01-01

    The extensive empirical literature analyzing productivity spillovers from foreign direct investment to local firms provides inconclusive results. Some studies find that foreign presence has a positive impact on the productivity of domestic firms, while others find no evidence or a negative effect...... for industrialized countries in the 1990s. Transition economies may experience spillovers, but these have been declining in recent years. Keywords: developing countries, transition economies, spillovers, foreign direct investment, technology transfer, meta-analysis...

  11. Urologic robots and future directions

    OpenAIRE

    Mozer, Pierre; Troccaz, Jocelyne; Stoianovici, Dan

    2008-01-01

    International audience; PURPOSE OF REVIEW: Robot-assisted laparoscopic surgery in urology has gained immense popularity with the daVinci system, but a lot of research teams are working on new robots. The purpose of this study is to review current urologic robots and present future development directions. RECENT FINDINGS: Future systems are expected to advance in two directions: improvements of remote manipulation robots and developments of image-guided robots. SUMMARY: The final goal of robot...

  12. Direction of escape in reindeer

    OpenAIRE

    Baskin, Leonid M.; Terje Skogland

    1997-01-01

    We tested the hypothesis that reindeer prefer to run uphill and upwind when escaping from man. Groups of wild and feral reindeer in Norway, Svalbard and on Wrangel Island were approached and their behaviour and direction of escape were recorded. Two stages of interaction with man were studied: first flight and final withdrawal. First flights proved to be away from man, upwind and uphill. Most final withdrawals were in the direction reindeer were moving when first observed.

  13. Direction of escape in reindeer

    Directory of Open Access Journals (Sweden)

    Leonid M. Baskin

    1997-04-01

    Full Text Available We tested the hypothesis that reindeer prefer to run uphill and upwind when escaping from man. Groups of wild and feral reindeer in Norway, Svalbard and on Wrangel Island were approached and their behaviour and direction of escape were recorded. Two stages of interaction with man were studied: first flight and final withdrawal. First flights proved to be away from man, upwind and uphill. Most final withdrawals were in the direction reindeer were moving when first observed.

  14. Improved directional-distance filter

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    This paper proposes a new spatial-distance weighting function.By combining the weighting function and the traditional directional-distance filter (DDF) in a novel way,a new vector filter-the adaptive distance-weighted directional-distance filter (ADWDDF)-is presented.The experimental results show that the proposed solution provides better filtering performance and preserves better image chromaticity and edge or detail information compared with the traditional DDF and some other typical vector filters.

  15. Economic impact of chikungunya epidemic: out-of-pocket health expenditures during the 2007 outbreak in Kerala, India.

    Science.gov (United States)

    Vijayakumar, K; George, B; Anish, T S; Rajasi, R S; Teena, M J; Sujina, C M

    2013-01-01

    The southern state of Kerala, India was seriously affected by a chikungunya epidemic in 2007. As this outbreak was the first of its kind, the morbidity incurred by the epidemic was a challenge to the state's public health system. A cross sectional survey was conducted in five districts of Kerala that were seriously affected by the epidemic, using a two-stage cluster sampling technique to select households, and the patients were identified using a syndromic case definition. We calculated the direct health expenditure of families and checked whether it exceed the margins of catastrophic health expenditure (CHE). The median (IQR) total out-of-pocket (OOP) health expenditure in the study population was USD7.4 (16.7). The OOP health expenditure did not show any significant association with increasing per-capita monthly income.The major share (47.4%) of the costs was utilized for buying medicines, but costs for transportation (17.2%), consultations (16.6%), and diagnoses (9.9%) also contributed significantly to the total OOP health expenditure. The OOP health expenditure was high in private sector facilities, especially in tertiary care hospitals. For more than 15% of the respondents, the OOP was more than double their average monthly family income. The chikungunya outbreak of 2007 had significantly contributed to the OOP expenditure of the affected community in Kerala.The OOP health expenditure incurred was high, irrespective of the level of income. Governments should attempt to ensure comprehensive financial protection by covering the costs of care, along with loss of productivity.

  16. CYBER HOSTILITIES: CIVILIAN DIRECT PARTICIPATION

    Directory of Open Access Journals (Sweden)

    Dan-Iulian VOITAȘEC

    2016-06-01

    Full Text Available The manner in which hostilities are being conducted has changed in recent years. The battle field has transpired beyond the physical realm and now has a virtual component. Because of this, it is now easier than ever for civilians to get involved in hostilities. International Humanitarian Law applies to all situations of armed conflict and according to the principle of distinction, the parties to the conflict must, at all times, distinguish between civilians and combatants. The problem arises when the line between combatants and civilians starts to get blurry. Direct civilian participation in hostilities has been addressed in both Additional Protocols to the Geneva Conventions of 1949 and in 2009 the International Committee of the Red Cross published the Interpretive guidance on the notion of Direct Participation in Hostilities under international humanitarian law. Another document that addresses the problem of civilian direct participation is the Tallinn Manual on the International Law Applicable to Cyber Warfare prepared by an international group of experts at the invitation of the NATO Cooperative Cyber Defence Centre of Excellence in 2013. The guide prepared by the ICRC addresses the problem of civilian direct participation during conventional situations of armed conflict, while the Tallinn Manual addresses direct participation in situations of cyber warfare. The purpose of this paper is to study the application of civilian direct participation to situations of cyber warfare.

  17. Direct conversion of fusion energy

    Energy Technology Data Exchange (ETDEWEB)

    Johansson, Markus

    2003-03-01

    Deuterium and tritium are expected to be used as fuel in the first fusion reactors. Energy is released as kinetic energy of ions and neutrons, when deuterium reacts with tritium. One way to convert the kinetic energy to electrical energy, is to let the ions and neutrons hit the reactor wall and convert the heat that is caused by the particle bombardment to electrical energy with ordinary thermal conversion. If the kinetic energy of the ions instead is converted directly to electrical energy, a higher efficiency of the energy conversion is possible. The majority of the fusion energy is released as kinetic energy of neutrons, when deuterium reacts with tritium. Fusion reactions such as the D-D reactions, the D-{sup 3}He reaction and the p-{sup 11}B reaction, where a larger part of the fusion energy becomes kinetic energy of charged particles, appears therefore more suitable for direct conversion. Since they have lower reactivity than the D-T reaction, they need a larger {beta}B{sup 2}{sub 0} to give sufficiently high fusion power density. Because of this, the fusion configurations spherical torus (ST) and field-reversed configuration (FRC), where high {beta} values are possible, appear interesting. Rosenbluth and Hinton come to the conclusion that efficient direct conversion isn't possible in closed field line systems and that open geometries, which facilitate direct conversion, provide inadequate confinement for D-{sup 3}He. It is confirmed in this study that it doesn't seem possible to achieve as high direct conversion efficiency in closed systems as in open systems. ST and FRC fusion power plants that utilize direct conversion seem however interesting. Calculations with the help of Maple indicate that the reactor parameters needed for a D-D ST and a D{sub 3} He ST hopefully are possible to achieve. The best energy conversion option for a D-D or D{sub 3} He ST appears to be direct electrodynamic conversion (DEC) together with ordinary thermal conversion

  18. Directive and Non-Directive Movement in Child Therapy.

    Science.gov (United States)

    Krason, Katarzyna; Szafraniec, Grazyna

    1999-01-01

    Presents a new authorship method of child therapy based on visualization through motion. Maintains that this method stimulates motor development and musical receptiveness, and promotes personality development. Suggests that improvised movement to music facilitates the projection mechanism and that directed movement starts the channeling phase.…

  19. Photoelectrochemical based direct conversion systems

    Energy Technology Data Exchange (ETDEWEB)

    Kocha, S.; Arent, D.; Peterson, M. [National Renewable Energy Lab., Golden, CO (United States)] [and others

    1995-09-01

    The goal of this research is to develop a stable, cost effective, photoelectrochemical based system that will split water upon illumination, producing hydrogen and oxygen directly, using sunlight as the only energy input. This type of direct conversion system combines a photovoltaic material and an electrolyzer into a single monolithic device. We report on our studies of two multifunction multiphoton photoelectrochemical devices, one based on the ternary semiconductor gallium indium phosphide, (GaInP{sub 2}), and the other one based on amorphous silicon carbide. We also report on our studies of the solid state surface treatment of GaInP{sub 2} as well as our continuing effort to develop synthetic techniques for the attachment of transition metal complexes to the surface of semiconductor electrodes. All our surface studies are directed at controlling the interface energetics and forming stable catalytic surfaces.

  20. Direct vs. Indirect Moral Enhancement.

    Science.gov (United States)

    Schaefer, G Owen

    2015-09-01

    Moral enhancement is an ostensibly laudable project. Who wouldn't want people to become more moral? Still, the project's approach is crucial. We can distinguish between two approaches for moral enhancement: direct and indirect. Direct moral enhancements aim at bringing about particular ideas, motives or behaviors. Indirect moral enhancements, by contrast, aim at making people more reliably produce the morally correct ideas, motives or behaviors without committing to the content of those ideas, motives and/or actions. I will argue, on Millian grounds, that the value of disagreement puts serious pressure on proposals for relatively widespread direct moral enhancement. A more acceptable path would be to focus instead on indirect moral enhancements while staying neutral, for the most part, on a wide range of substantive moral claims. I will outline what such indirect moral enhancement might look like, and why we should expect it to lead to general moral improvement.

  1. Direct-fuelled fuel cells

    Science.gov (United States)

    Waidhas, M.; Drenckhahn, W.; Preidel, W.; Landes, H.

    Fuel supply is one important problem to be solved for commercial application of fuel cell technology. Conventional fuel-cell types require hydrogen as the fuel, which has to be free from impurities when operated at temperatures below 100 °C. The storage and distribution of this explosive and extremely fugitive gas is one of the open questions in the context of a customer-oriented broad commercial market. The direct-fuelled fuel cells (DMFCs) overcome the hydrogen specific restrictions. They are capable of directly using natural gas or fuels which are liquid under ambient conditions. In this paper the different options from direct-fuelled systems are described and their general aspects discussed. The state-of-the-art at Siemens in this field, and also the remaining technical questions are outlined as a basis for assessing future applications.

  2. Sensing roughness and polish direction

    DEFF Research Database (Denmark)

    Jakobsen, Michael Linde; Olesen, Anders Sig; Larsen, Henning Engelbrecht;

    2016-01-01

    needs information about the RMS-value of the surface roughness and the current direction of the scratches introduced by the polishing process. The RMS-value indicates to the operator how far he is from the final finish, and the scratch orientation is often specified by the customer in order to avoid...... complications during the casting process. In this work we present a method for measuring the RMS-values of the surface roughness while simultaneously determining the polishing direction. We are mainly interested in the RMS-values in the range from 0 – 100 nm, which corresponds to the finish categories of A1, A2...... and A3 (Finishing guide, Bales). Based on simple intensity measurements, we estimate the RMS-value of the surface roughness, and by using a sectioned annually shaped photo-detector to collect the scattered light, we can determine the direction of polishing and distinguish light scattered from random...

  3. Direct Methanol Fuel Cell, DMFC

    Directory of Open Access Journals (Sweden)

    Amornpitoksuk, P.

    2003-09-01

    Full Text Available Direct Methanol Fuel Cell, DMFC is a kind of fuel cell using methanol as a fuel for electric producing. Methanol is low cost chemical substance and it is less harmful than that of hydrogen fuel. From these reasons it can be commercial product. The electrocatalytic reaction of methanol fuel uses Pt-Ru metals as the most efficient catalyst. In addition, the property of membrane and system designation are also effect to the fuel cell efficient. Because of low power of methanol fuel cell therefore, direct methanol fuel cell is proper to use for the energy source of small electrical devices and vehicles etc.

  4. On Directed Information and Gambling

    CERN Document Server

    Permuter, Haim H; Weissman, Tsachy

    2008-01-01

    We study the problem of gambling in horse races with causal side information and show that Massey's directed information characterizes the increment in the maximum achievable capital growth rate due to the availability of side information. This result gives a natural interpretation of directed information $I(Y^n \\to X^n)$ as the amount of information that $Y^n$ \\emph{causally} provides about $X^n$. Extensions to stock market portfolio strategies and data compression with causal side information are also discussed.

  5. PROTOTIPE VIDEO EDITOR DENGAN MENGGUNAKAN DIRECT X DAN DIRECT SHOW

    Directory of Open Access Journals (Sweden)

    Djoni Haryadi Setiabudi

    2004-01-01

    Full Text Available Technology development had given people the chance to capture their memorable moments in video format. A high quality digital video is a result of a good editing process. Which in turn, arise the new need of an editor application. In accordance to the problem, here the process of making a simple application for video editing needs. The application development use the programming techniques often applied in multimedia applications, especially video. First part of the application will begin with the video file compression and decompression, then we'll step into the editing part of the digital video file. Furthermore, the application also equipped with the facilities needed for the editing processes. The application made with Microsoft Visual C++ with DirectX technology, particularly DirectShow. The application provides basic facilities that will help the editing process of a digital video file. The application will produce an AVI format file after the editing process is finished. Through the testing process of this application shows the ability of this application to do the 'cut' and 'insert' of video files in AVI, MPEG, MPG and DAT formats. The 'cut' and 'insert' process only can be done in static order. Further, the aplication also provide the effects facility for transition process in each clip. Lastly, the process of saving the new edited video file in AVI format from the application. Abstract in Bahasa Indonesia : Perkembangan teknologi memberi kesempatan masyarakat untuk mengabadikan saat - saat yang penting menggunakan video. Pembentukan video digital yang baik membutuhkan proses editing yang baik pula. Untuk melakukan proses editing video digital dibutuhkan program editor. Berdasarkan permasalahan diatas maka pada penelitian ini dibuat prototipe editor sederhana untuk video digital. Pembuatan aplikasi memakai teknik pemrograman di bidang multimedia, khususnya video. Perencanaan dalam pembuatan aplikasi tersebut dimulai dengan pembentukan

  6. Direct reciprocity in structured populations

    NARCIS (Netherlands)

    C.M. van Veelen; J. García; D.G. Rand; M.A. Nowak

    2012-01-01

    Reciprocity and repeated games have been at the center of attention when studying the evolution of human cooperation. Direct reciprocity is considered to be a powerful mechanism for the evolution of cooperation, and it is generally assumed that it can lead to high levels of cooperation. Here we expl

  7. Direct Energy Conversion Literature Abstracts

    Science.gov (United States)

    1962-12-01

    here-between in contact with Tecnica Ital.26:65-71, Jan/Feb.1961. said second electrode. (U.S. Patent Off. Off. Gaz. 773:260, Dec.5,1961). In Italian...DETERMINATION OF MOLECULAR WEIGHT. Mikrochim. Acta p.457-466, 3168 S 1951. Huber, H. and Bensimon, J. SUR LA CONVERSION DIRECTE DE CHALEUR EN (In English

  8. Broadband terahertz fiber directional coupler

    DEFF Research Database (Denmark)

    Nielsen, Kristian; Rasmussen, Henrik K.; Jepsen, Peter Uhd

    2010-01-01

    We present the design of a short broadband fiber directional coupler for terahertz (THz) radiation and demonstrate a 3 dB coupler with a bandwidth of 0:6 THz centered at 1:4 THz. The broadband coupling is achieved by mechanically downdoping the cores of a dual-core photonic crystal fiber...

  9. Directional Dependence in Developmental Research

    Science.gov (United States)

    von Eye, Alexander; DeShon, Richard P.

    2012-01-01

    In this article, we discuss and propose methods that may be of use to determine direction of dependence in non-normally distributed variables. First, it is shown that standard regression analysis is unable to distinguish between explanatory and response variables. Then, skewness and kurtosis are discussed as tools to assess deviation from…

  10. Sensing roughness and polish direction

    Science.gov (United States)

    Jakobsen, M. L.; Olesen, A. S.; Larsen, H. E.; Stubager, J.; Hanson, S. G.; Pedersen, T. F.; Pedersen, H. C.

    2016-04-01

    As a part of the work carried out on a project supported by the Danish council for technology and innovation, we have investigated the option of smoothing standard CNC machined surfaces. In the process of constructing optical prototypes, involving custom-designed optics, the development cost and time consumption can become relatively large numbers in a research budget. Machining the optical surfaces directly is expensive and time consuming. Alternatively, a more standardized and cheaper machining method can be used, but then the object needs to be manually polished. During the polishing process the operator needs information about the RMS-value of the surface roughness and the current direction of the scratches introduces by the polishing process. The RMS-value indicates to the operator how far he is from the final finish, and the scratch orientation is often specified by the customer in order to avoid complications during the casting process. In this work we present a method for measuring the RMS-values of the surface roughness while simultaneously determining the polishing direction. We are mainly interested in the RMS-values in the range from 0 - 100 nm, which corresponds to the finish categories of A1, A2 and A3. Based on simple intensity measurements we estimates the RMS-value of the surface roughness, and by using a sectioned annual photo-detector to collect the scattered light we can determine the direction of polishing and distinguish light scattered from random structures and light scattered from scratches.

  11. Teaching Ethics: A Direct Approach.

    Science.gov (United States)

    Penn, William Y., Jr.

    1990-01-01

    Compares five designs of an undergraduate ethics course at Saint Edward's University (Texas) in a 5-year study involving 318 students. Reveals the effectiveness of directly targeting and teaching in tandem the elements of moral reasoning. Bases study on Lawrence Kohlberg's moral development theory. Argues that this approach best develops moral…

  12. Popular support for direct democracy

    NARCIS (Netherlands)

    Donovan, Todd; Karp, J.A.

    2006-01-01

    The expanding use of direct democracy in many established democracies reflects a desire to provide citizens with more opportunities to be involved in the political process. These changes are assumed to be embraced by those who demand greater citizen involvement, though the underlining motivation

  13. Evolutionary trends in directional hearing

    DEFF Research Database (Denmark)

    Carr, Catherine E; Christensen-Dalsgaard, Jakob

    2016-01-01

    Tympanic hearing is a true evolutionary novelty that arose in parallel within early tetrapods. We propose that in these tetrapods, selection for sound localization in air acted upon pre-existing directionally sensitive brainstem circuits, similar to those in fishes. Auditory circuits in birds...... interactions between coding strategies and evolutionary history....

  14. Directivity of basic linear arrays

    DEFF Research Database (Denmark)

    Bach, Henning

    1970-01-01

    For a linear uniform array ofnelements, an expression is derived for the directivity as a function of the spacing and the phase constants. The cases of isotropic elements, collinear short dipoles, and parallel short dipoles are included. The formula obtained is discussed in some detail and contour...

  15. Direct spinning of fiber supercapacitor.

    Science.gov (United States)

    Xu, Tong; Ding, Xiaoteng; Liang, Yuan; Zhao, Yang; Chen, Nan; Qu, Liangti

    2016-06-16

    A direct wet spinning approach is demonstrated for facile and continuous fabrication of a whole fiber supercapacitor using a microfluidic spinneret. The resulting fiber supercapacitor shows good electrochemical properties and possesses high flexibility and mechanical stability. This strategy paves the way for large-scale continuous production of fiber supercapacitors for weavable electronics.

  16. Neurolaw and Direct Brain Interventions

    NARCIS (Netherlands)

    Vincent, N.A.

    2012-01-01

    This issue of Criminal Law and Philosophy contains three papers on a topic of increasing importance within the field of ‘‘neurolaw’’—namely, the implications for criminal law of direct brain intervention based mind altering techniques (DBI’s). To locate these papers’ topic within a broader context,

  17. The 1990 direct support infrastructure

    Science.gov (United States)

    1978-01-01

    The airport and cargo terminal were individually analyzed in depth as the principal direct infrastructure components having cross impacts with aircraft carrying cargo. Containerization was also addressed in depth as an infrastructure component since it categorically is linked with and cross impacted by the aircraft, the cargo terminal, the surface transport system, the shipper and consignee, and the actual cargo being moved.

  18. Direct Employee Involvement Quality (DEIQ)

    NARCIS (Netherlands)

    Torka, Nicole; Woerkom, van Marianne; Looise, Jan-Kees

    2008-01-01

    This paper focuses on one aspect of human resource management (HRM) that is important for innovative employee behaviour: direct employee involvement quality (DEIQ). However, research has also shown that employee involvement is often in serious need of improvement. This paper presents evidence from t

  19. Self directed and lifelong learning.

    Science.gov (United States)

    Alexander, Sylvia; Kernohan, George; McCullagh, Paul

    2004-01-01

    Given the many changes that occur in medicine, health care and information technologies we need to prepare all our students to engage in self directed and life long learning. There is considerable opportunity for self-directed and lifelong learning in health informatics bringing together students in exciting global learning environments, where they have much greater freedom and flexibility in their studies and potentially a wider variety of resources available to them. Self-directed learning focuses on the process by which adults take control of their own learning, in particular how they set their own learning goals, locate appropriate resources, decide on which learning methods to use and evaluate their progress. Lifelong learning happens in a variety of formal and informal settings building on both intentional and incidental learning experiences. In a lifelong learning situation the tutor must relinquish the role of expert and assume the role of facilitator, guiding learners to uncover their own knowledge. Against a back drop of rapid advances in technology which can be used to both deliver course materials and provide enhanced learning opportunities, this chapter outlines the pedagogic principles and practices which underpin self-directed and lifelong learning.

  20. Soliton switching in directional couplers

    NARCIS (Netherlands)

    Valkering, T.P.; Hoekstra, Hugo; de Boer, Pieter-Tjerk

    1999-01-01

    The mechanism of pulse switching is investigated analytically and numerically for a family of initial conditions with a solitonlike pulse in one channel and no signal on the other channel of the coupler. This investigation is performed directly in the coupled nonlinear Schroedinger equations that

  1. Sampling properties of directed networks

    CERN Document Server

    Son, Seung-Woo; Bizhani, Golnoosh; Foster, David V; Grassberger, Peter; Paczuski, Maya

    2012-01-01

    For many real-world networks only a small "sampled" version of the original network may be investigated; those results are then used to draw conclusions about the actual system. Variants of breadth-first search (BFS) sampling, which are based on epidemic processes, are widely used. Although it is well established that BFS sampling fails, in most cases, to capture the IN-component(s) of directed networks, a description of the effects of BFS sampling on other topological properties are all but absent from the literature. To systematically study the effects of sampling biases on directed networks, we compare BFS sampling to random sampling on complete large-scale directed networks. We present new results and a thorough analysis of the topological properties of seven different complete directed networks (prior to sampling), including three versions of Wikipedia, three different sources of sampled World Wide Web data, and an Internet-based social network. We detail the differences that sampling method and coverage...

  2. Direct detection of dark matter axions with directional sensitivity

    CERN Document Server

    Irastorza, Igor G

    2012-01-01

    We study the directional effect of the expected axion dark matter signal in a resonant cavity of an axion haloscope detector, for cavity geometries not satisfying the condition that the axion de Broglie wavelength is much larger than the cavity dimensions. We focus on long thin cavities immersed in dipole magnets and find, for appropriately chosen cavity lengths, an O(1) modulation of the signal with the cavity orientation with respect the momentum distribution of the relic axion background predicted by the isothermal sphere model for the galactic dark matter halo. This effect can be exploited to design directional axion dark matter detectors, providing an unmistakable signature of the extraterrestrial origin of a possible positive detection. Moreover, the precise shape of the modulation may give information of the galactic halo distribution and, for specific halo models, give extra sensitivity for higher axion masses.

  3. Breakdown of interdependent directed networks.

    Science.gov (United States)

    Liu, Xueming; Stanley, H Eugene; Gao, Jianxi

    2016-02-02

    Increasing evidence shows that real-world systems interact with one another via dependency connectivities. Failing connectivities are the mechanism behind the breakdown of interacting complex systems, e.g., blackouts caused by the interdependence of power grids and communication networks. Previous research analyzing the robustness of interdependent networks has been limited to undirected networks. However, most real-world networks are directed, their in-degrees and out-degrees may be correlated, and they are often coupled to one another as interdependent directed networks. To understand the breakdown and robustness of interdependent directed networks, we develop a theoretical framework based on generating functions and percolation theory. We find that for interdependent Erdős-Rényi networks the directionality within each network increases their vulnerability and exhibits hybrid phase transitions. We also find that the percolation behavior of interdependent directed scale-free networks with and without degree correlations is so complex that two criteria are needed to quantify and compare their robustness: the percolation threshold and the integrated size of the giant component during an entire attack process. Interestingly, we find that the in-degree and out-degree correlations in each network layer increase the robustness of interdependent degree heterogeneous networks that most real networks are, but decrease the robustness of interdependent networks with homogeneous degree distribution and with strong coupling strengths. Moreover, by applying our theoretical analysis to real interdependent international trade networks, we find that the robustness of these real-world systems increases with the in-degree and out-degree correlations, confirming our theoretical analysis.

  4. Object-oriented philosophy in designing adaptive finite-element package for 3D elliptic deferential equations

    Science.gov (United States)

    Zhengyong, R.; Jingtian, T.; Changsheng, L.; Xiao, X.

    2007-12-01

    Although adaptive finite-element (AFE) analysis is becoming more and more focused in scientific and engineering fields, its efficient implementations are remain to be a discussed problem as its more complex procedures. In this paper, we propose a clear C++ framework implementation to show the powerful properties of Object-oriented philosophy (OOP) in designing such complex adaptive procedure. In terms of the modal functions of OOP language, the whole adaptive system is divided into several separate parts such as the mesh generation or refinement, a-posterior error estimator, adaptive strategy and the final post processing. After proper designs are locally performed on these separate modals, a connected framework of adaptive procedure is formed finally. Based on the general elliptic deferential equation, little efforts should be added in the adaptive framework to do practical simulations. To show the preferable properties of OOP adaptive designing, two numerical examples are tested. The first one is the 3D direct current resistivity problem in which the powerful framework is efficiently shown as only little divisions are added. And then, in the second induced polarization£¨IP£©exploration case, new adaptive procedure is easily added which adequately shows the strong extendibility and re-usage of OOP language. Finally we believe based on the modal framework adaptive implementation by OOP methodology, more advanced adaptive analysis system will be available in future.

  5. Setting a personal career direction.

    Science.gov (United States)

    McCurdy, Fredrick A; Marcdante, Karen

    2003-01-01

    In summary, we believe that both you and your organization should have a set of core values, a well-defined mission (core purpose), and a vision of the future. Ideally, your projects and activities should be congruent with your mission and values, you should be pursuing your vision, and all of this should be congruent with the organization mission and values. Practically speaking, most individuals we have worked with over the years find themselves in two different groups at this point in the exercise. The minority find that their personal mission is not at all similar to the mission of their current organization and they find it necessary to seriously reevaluate their personal career direction. Sometimes, this results in them finding some other place to work. On the other hand, the majority discover their personal mission is in reasonable agreement with that of their organization. For both, this exercise has helped them clarify and better manage their personal career direction.

  6. Plasma dark matter direct detection

    CERN Document Server

    Clarke, Jackson D

    2015-01-01

    Dark matter in spiral galaxies like the Milky Way may take the form of a dark plasma. Hidden sector dark matter charged under an unbroken $U(1)'$ gauge interaction provides a simple and well defined particle physics model realising this possibility. The assumed $U(1)'$ neutrality of the Universe then implies (at least) two oppositely charged dark matter components with self-interactions mediated via a massless "dark photon" (the $U(1)'$ gauge boson). In addition to nuclear recoils such dark matter can give rise to keV electron recoils in direct detection experiments. In this context, the detailed physical properties of the dark matter plasma interacting with the Earth is required. This is a complex system, which is here modelled as a fluid governed by the magnetohydrodynamic equations. These equations are numerically solved for some illustrative examples, and implications for direct detection experiments discussed. In particular, the analysis presented here leaves open the intriguing possibility that the DAMA...

  7. Multimode waveguide based directional coupler

    Science.gov (United States)

    Ahmed, Rajib; Rifat, Ahmmed A.; Sabouri, Aydin; Al-Qattan, Bader; Essa, Khamis; Butt, Haider

    2016-07-01

    The Silicon-on-Insulator (SOI) based platform overcomes limitations of the previous copper and fiber based technologies. Due to its high index difference, SOI waveguide (WG) and directional couplers (DC) are widely used for high speed optical networks and hybrid Electro-Optical inter-connections; TE00-TE01, TE00-TE00 and TM00-TM00 SOI direction couplers are designed with symmetrical and asymmetrical configurations to couple with TE00, TE01 and TM00 in a multi-mode semi-triangular ring-resonator configuration which will be applicable for multi-analyte sensing. Couplers are designed with effective index method and their structural parameters are optimized with consideration to coupler length, wavelength and polarization dependence. Lastly, performance of the couplers are analyzed in terms of cross-talk, mode overlap factor, coupling length and coupling efficiency.

  8. Directed information measures in neuroscience

    CERN Document Server

    Vicente, Raul; Lizier, Joseph

    2014-01-01

    Analysis of information transfer has found rapid adoption in neuroscience, where a highly dynamic transfer of information continuously runs on top of the brain's slowly-changing anatomical connectivity. Measuring such transfer is crucial to understanding how flexible information routing and processing give rise to higher cognitive function. Directed Information Measures in Neuroscience reviews recent developments of concepts and tools for measuring information transfer, their application to neurophysiological recordings and analysis of interactions. Written by the most active researchers in the field the book discusses the state of the art, future prospects and challenges on the way to an efficient assessment of neuronal information transfer. Highlights include the theoretical quantification and practical estimation of information transfer, description of transfer locally in space and time, multivariate directed measures, information decomposition among a set of stimulus/responses variables, and the relation ...

  9. Model Independent Direct Detection Analyses

    CERN Document Server

    Fitzpatrick, A Liam; Katz, Emanuel; Lubbers, Nicholas; Xu, Yiming

    2012-01-01

    Following the construction of the general effective theory for dark matter direct detection in 1203.3542, we perform an analysis of the experimental constraints on the full parameter space of elastically scattering dark matter. We review the prescription for calculating event rates in the general effective theory and discuss the sensitivity of various experiments to additional nuclear responses beyond the spin-independent (SI) and spin-dependent (SD) couplings: an angular-momentum-dependent (LD) and spin-and-angular-momentum-dependent (LSD) response, as well as a distinction between transverse and longitudinal spin-dependent responses. We consider the effect of interference between different operators and in particular look at directions in parameter space where such cancellations lead to holes in the sensitivity of individual experiments. We explore the complementarity of different experiments by looking at the improvement of bounds when experiments are combined. Finally, our scan through parameter space sho...

  10. Theology Today - Currents and Directions

    OpenAIRE

    Fergusson, David

    2011-01-01

    While more fragmented than in mid-20th century, recent trends and directions reveal some dominant approaches and particular sub-areas that have become the focus of significant attention. Although overlapping and intersecting, these are discernible both methodologically and thematically. Approaches include a commitment to cross-disciplinarity, contextuality, strategies of retrieval, articulation of confessional identity, and the re-appropriation of liberalism. Important sub-areas include the r...

  11. Direct Fuel Injector Temporal Measurements

    Science.gov (United States)

    2014-10-01

    optimize engine performance and emissions. Fuel injectors contain an actuator, pintle (or needle), and nozzle. The most common actuator is a solenoid ...Introduction Fuel injectors have a long history in metering fuel in modern engines by either port fuel injection (PFI) or direct fuel injection (DFI...Compared with a carburetor, fuel injectors have more accurate fuel delivering capability, thus giving engineers and technicians more flexibility to

  12. Directivity of a simplified aeroengine

    OpenAIRE

    Mattei, Pierre-Olivier

    2006-01-01

    International audience; This paper presents theoretical and numerical results on the high frequency directivity of an aeroengine under flight conditions. In this paper, two different theories, based on a Kirchhoff approximation for semi-infinite cylinders, are combined to obtain the far field sound pressure radiated into the whole surrounding space. Although the geometric description of the engine is simplified - in particular, the annular exhaust is not taken into account - it includes some ...

  13. Relativistic propulsion using directed energy

    Science.gov (United States)

    Bible, Johanna; Johansson, Isabella; Hughes, Gary B.; Lubin, Philip M.

    2013-09-01

    We propose a directed energy orbital planetary defense system capable of heating the surface of potentially hazardous objects to the evaporation point as a futuristic but feasible approach to impact risk mitigation. The system is based on recent advances in high efficiency photonic systems. The system could also be used for propulsion of kinetic or nuclear tipped asteroid interceptors or other interplanetary spacecraft. A photon drive is possible using direct photon pressure on a spacecraft similar to a solar sail. Given a laser power of 70GW, a 100 kg craft can be propelled to 1AU in approximately 3 days achieving a speed of 0.4% the speed of light, and a 10,000 kg craft in approximately 30 days. We call the system DE-STAR for Directed Energy System for Targeting of Asteroids and exploRation. DE-STAR is a modular phased array of solid-state lasers, powered by photovoltaic conversion of sunlight. The system is scalable and completely modular so that sub elements can be built and tested as the technology matures. The sub elements can be immediately utilized for testing as well as other applications including space debris mitigation. The ultimate objective of DE-STAR would be to begin direct asteroid vaporization and orbital modification starting at distances beyond 1 AU. Using phased array technology to focus the beam, the surface spot temperature on the asteroid can be raised to more than 3000K, allowing evaporation of all known substances. Additional scientific uses of DE-STAR are also possible.

  14. Direct reciprocity in structured populations.

    Science.gov (United States)

    van Veelen, Matthijs; García, Julián; Rand, David G; Nowak, Martin A

    2012-06-19

    Reciprocity and repeated games have been at the center of attention when studying the evolution of human cooperation. Direct reciprocity is considered to be a powerful mechanism for the evolution of cooperation, and it is generally assumed that it can lead to high levels of cooperation. Here we explore an open-ended, infinite strategy space, where every strategy that can be encoded by a finite state automaton is a possible mutant. Surprisingly, we find that direct reciprocity alone does not lead to high levels of cooperation. Instead we observe perpetual oscillations between cooperation and defection, with defection being substantially more frequent than cooperation. The reason for this is that "indirect invasions" remove equilibrium strategies: every strategy has neutral mutants, which in turn can be invaded by other strategies. However, reciprocity is not the only way to promote cooperation. Another mechanism for the evolution of cooperation, which has received as much attention, is assortment because of population structure. Here we develop a theory that allows us to study the synergistic interaction between direct reciprocity and assortment. This framework is particularly well suited for understanding human interactions, which are typically repeated and occur in relatively fluid but not unstructured populations. We show that if repeated games are combined with only a small amount of assortment, then natural selection favors the behavior typically observed among humans: high levels of cooperation implemented using conditional strategies.

  15. Direct Utilization of Geothermal Energy

    Directory of Open Access Journals (Sweden)

    John W. Lund

    2010-08-01

    Full Text Available The worldwide application of geothermal energy for direct utilization is reviewed. This paper is based on the world update for direct-use presented at the World Geothermal Congress 2010 in Bali, Indonesia (WGC2010 [1] which also includes material presented at three world geothermal congresses in Italy, Japan and Turkey (WGC95, WGC2000 and WGC2005. This report is based on country update papers prepared for WGC2010 and data from other sources. Final update papers were received from 70 countries of which 66 reported some direct utilization of geothermal energy for WGC2010. Twelve additional countries were added to the list based on other sources of information. The 78 countries having direct utilization of geothermal energy, is a significant increase from the 72 reported in 2005, the 58 reported in 2000, and the 28 reported in 1995. An estimate of the installed thermal power for direct utilization at the end of 2009, reported from WGC2010 is 48,493 MWt, almost a 72 % increased over the 2005 data, growing at a compound rate of 11.4% annually with a capacity factor of 0.28. The thermal energy used is 423,830 TJ/year (117,740 GWh/yr, about a 55% increase over 2005, growing at a compound rate of 9.2% annually. The distribution of thermal energy used by category is approximately 47.2% for ground-source heat pumps, 25.8% for bathing and swimming (including balneology, 14.9% for space heating (of which 85% is for district heating, 5.5% for greenhouses and open ground heating, 2.8% for industrial process heating, 2.7% for aquaculture pond and raceway heating, 0.4% for agricultural drying, 0.5% for snow melting and cooling, and 0.2% for other uses. Energy savings amounted to 250 million barrels (38 million tonnes of equivalent oil annually, preventing 33 million tonnes of carbon and 107 million tonnes of CO2 being release to the atmosphere which includes savings in geothermal heat pump cooling (compared to using fuel oil to generate electricity.

  16. Understanding the direct and indirect costs of patients with schizophrenia [v2; ref status: indexed, http://f1000r.es/5ow

    Directory of Open Access Journals (Sweden)

    Kazuhiro Tajima-Pozo

    2015-08-01

    Full Text Available Background: Schizophrenia is a disabling mental disorder with high prevalence and that usually  requires long-term follow-up and expensive lifelong treatment. The cost of schizophrenia treatment consumes a significant amount of the health services' budget in western countries. Objective: The aim of the study was to find out about the costs related to schizophrenia across different european countries and compare them. Results: Schizophrenia treatment costs an estimated 18 billion euros annually worldwide. The direct costs associated with medical help are only part of the total expenditure. The indirect costs are an equally (or even moreimportant part of the total cost. These expenses are related to the lack of productivity of schizophrenic patients and the cost that relatives have to bear as a result of taking care of their affected relatives. Conclusions: Although data on the cost of schizophrenia may vary slightly between different european countries, the general conclusion that can be drawn is that schizophrenia is a very costly disorder. Not only because of direct costs related to medical procedures, but also due to the non-medical (indirect costs. Together this suggests the need to investigate cost-efficient strategies that could provide a better outcome for schizophrenic patients, as well as the people who care for them.

  17. A convenient category for directed homotopy

    DEFF Research Database (Denmark)

    Fajstrup, Lisbeth; Rosický, J.

    2008-01-01

    We propose a convenient category for directed homotopy consisting of "directed" topological spaces generated by "directed" cubes. Its main advantage is that, like the category of topological spaces generated by simplices suggested by J. H. Smith, it is locally presentable.......We propose a convenient category for directed homotopy consisting of "directed" topological spaces generated by "directed" cubes. Its main advantage is that, like the category of topological spaces generated by simplices suggested by J. H. Smith, it is locally presentable....

  18. Directed energy deflection laboratory measurements

    Science.gov (United States)

    Brashears, Travis; Lubin, Phillip; Hughes, Gary B.; Meinhold, Peter; Suen, Jonathan; Batliner, Payton; Motta, Caio; Griswold, Janelle; Kangas, Miikka; Johansson, Isbella; Alnawakhtha, Yusuf; Prater, Kenyon; Lang, Alex; Madajian, Jonathan

    2015-09-01

    We report on laboratory studies of the effectiveness of directed energy planetary defense as a part of the DESTAR (Directed Energy System for Targeting of Asteroids and exploRation) program. DE-STAR [1][5][6] and DE-STARLITE [2][5][6] are directed energy "stand-off" and "stand-on" programs, respectively. These systems consist of a modular array of kilowatt-class lasers powered by photovoltaics, and are capable of heating a spot on the surface of an asteroid to the point of vaporization. Mass ejection, as a plume of evaporated material, creates a reactionary thrust capable of diverting the asteroid's orbit. In a series of papers, we have developed a theoretical basis and described numerical simulations for determining the thrust produced by material evaporating from the surface of an asteroid [1][2][3][4][5][6]. In the DE-STAR concept, the asteroid itself is used as the deflection "propellant". This study presents results of experiments designed to measure the thrust created by evaporation from a laser directed energy spot. We constructed a vacuum chamber to simulate space conditions, and installed a torsion balance that holds an "asteroid" sample. The sample is illuminated with a fiber array laser with flux levels up to 60 MW/m2 which allows us to simulate a mission level flux but on a small scale. We use a separate laser as well as a position sensitive centroid detector to readout the angular motion of the torsion balance and can thus determine the thrust. We compare the measured thrust to the models. Our theoretical models indicate a coupling coefficient well in excess of 100 μN/Woptical, though we assume a more conservative value of 80 μN/Woptical and then degrade this with an optical "encircled energy" efficiency of 0.75 to 60 μN/Woptical in our deflection modeling. Our measurements discussed here yield about 45 μN/Wabsorbed as a reasonable lower limit to the thrust per optical watt absorbed.

  19. Vitreous substitutes: challenges and directions

    Institute of Scientific and Technical Information of China (English)

    Qian-Ying; Gao; Yue; Fu; Yan-Nian; Hui

    2015-01-01

    The natural vitreous body has a fine structure and complex functions. The imitation of the natural vitreous body by vitreous substitutes is a challenging work for both researchers and ophthalmologists. Gases, silicone oil, heavy silicone oil and hydrogels, particularly the former two vitreous substitutes are clinically widely used with certain complications. Those, however, are not real artificial vitreous due to lack of structure and function like the natural vitreous body. This article reviews the situations, challenges, and future directions in the development of vitreous substitutes, particularly the experimental and clinical use of a new artificial foldable capsular vitreous body.

  20. Multi-directional productivity change

    DEFF Research Database (Denmark)

    Asmild, Mette; Balezentis, Tomas; Hougaard, Jens Leth

    2016-01-01

    In this paper we introduce an extension of the Malmquist total factor productivity index, which utilizes the Multi-directional Efficiency Analysis approach. This enables variable-specific analysis of productivity change as well as its components (efficiency change and technical change). The new...... approach is illustrated and compared to the conventional Data Envelopment Analysis Malmquist approach by considering a empirical data set on Lithuanian family farms. The results highlight that important differences in variable-specific performance of the farms can be hidden when using the conventional...

  1. Objects capture perceived gaze direction.

    Science.gov (United States)

    Lobmaier, Janek S; Fischer, Martin H; Schwaninger, Adrian

    2006-01-01

    The interpretation of another person's eye gaze is a key element of social cognition. Previous research has established that this ability develops early in life and is influenced by the person's head orientation, as well as local features of the person's eyes. Here we show that the presence of objects in the attended space also has an impact on gaze interpretation. Eleven normal adults identified the fixation points of photographed faces with a mouse cursor. Their responses were systematically biased toward the locations of nearby objects. This capture of perceived gaze direction probably reflects the attribution of intentionality and has methodological implications for research on gaze perception.

  2. Direct measurement of light waves.

    Science.gov (United States)

    Goulielmakis, E; Uiberacker, M; Kienberger, R; Baltuska, A; Yakovlev, V; Scrinzi, A; Westerwalbesloh, Th; Kleineberg, U; Heinzmann, U; Drescher, M; Krausz, F

    2004-08-27

    The electromagnetic field of visible light performs approximately 10(15) oscillations per second. Although many instruments are sensitive to the amplitude and frequency (or wavelength) of these oscillations, they cannot access the light field itself. We directly observed how the field built up and disappeared in a short, few-cycle pulse of visible laser light by probing the variation of the field strength with a 250-attosecond electron burst. Our apparatus allows complete characterization of few-cycle waves of visible, ultraviolet, and/or infrared light, thereby providing the possibility for controlled and reproducible synthesis of ultrabroadband light waveforms.

  3. Boltzmann, Darwin and Directionality theory

    Energy Technology Data Exchange (ETDEWEB)

    Demetrius, Lloyd A., E-mail: ldemetr@oeb.harvard.edu

    2013-09-01

    Boltzmann’s statistical thermodynamics is a mathematical theory which relates the macroscopic properties of aggregates of interacting molecules with the laws of their interaction. The theory is based on the concept thermodynamic entropy, a statistical measure of the extent to which energy is spread throughout macroscopic matter. Macroscopic evolution of material aggregates is quantitatively explained in terms of the principle: Thermodynamic entropy increases as the composition of the aggregate changes under molecular collision. Darwin’s theory of evolution is a qualitative theory of the origin of species and the adaptation of populations to their environment. A central concept in the theory is fitness, a qualitative measure of the capacity of an organism to contribute to the ancestry of future generations. Macroscopic evolution of populations of living organisms can be qualitatively explained in terms of a neo-Darwinian principle: Fitness increases as the composition of the population changes under variation and natural selection. Directionality theory is a quantitative model of the Darwinian argument of evolution by variation and selection. This mathematical theory is based on the concept evolutionary entropy, a statistical measure which describes the rate at which an organism appropriates energy from the environment and reinvests this energy into survivorship and reproduction. According to directionality theory, microevolutionary dynamics, that is evolution by mutation and natural selection, can be quantitatively explained in terms of a directionality principle: Evolutionary entropy increases when the resources are diverse and of constant abundance; but decreases when the resource is singular and of variable abundance. This report reviews the analytical and empirical support for directionality theory, and invokes the microevolutionary dynamics of variation and selection to delineate the principles which govern macroevolutionary dynamics of speciation and

  4. Directional Growth of Polymeric Nanowires

    Science.gov (United States)

    Thapa, Prem; Flanders, Bret

    2009-03-01

    This work establishes an innovative electrochemical approach to the template free growth of conducting polypyrrole and polythiophene wires. These polymeric wires exhibit a knobby structure, but persistent growth in a given direction up to 30 μm in length. A long-range component of the applied voltage signal defines the growth-path. Moreover, the presence of this component enables the growth of amorphous nanowires with wire-like geometries. Such wires are employed in a non-invasive methodology for attaining strong mechanical attachments to live cells. This capability is of potential use in the electro-mechanical probing of cell physiological processes.

  5. Direct application of geothermal energy

    Energy Technology Data Exchange (ETDEWEB)

    Reistad, G.M.

    1980-01-01

    An overall treatment of direct geothermal applications is presented with an emphasis on the above-ground engineering. The types of geothermal resources and their general extent in the US are described. The potential market that may be served with geothermal energy is considered briefly. The evaluation considerations, special design aspects, and application approaches for geothermal energy use in each of the applications are considered. The present applications in the US are summarized and a bibliography of recent studies and applications is provided. (MHR)

  6. Constant training in direct ophthalmoscopy

    Directory of Open Access Journals (Sweden)

    Younan HC

    2017-08-01

    Full Text Available Helen-Cara Younan, Rishi Iyer, Janaki Natasha DesaiFaculty of Medicine, Imperial College London, London, UKWe read with great interest the review by Ricci and Ferraz on the advances in training and practice in ophthalmoscopy simulation.1As final year medical students, we have recently experienced direct ophthalmoscopy teaching and agree with the authors that “simulation is a helpful tool in ophthalmoscopy training”.1 Indeed, in our experience, simulation is useful in teaching a wide variety of clinical skills including venepuncture, intravenous cannulation, and catheterization. We were taught all of these clinical skills in our first clinical year of study through use of simulation models. With regards to our direct ophthalmoscopy teaching, we were first taught to recognize the normal retina and different retinal pathologies using images, before practicing our technique and recognition of those images in a model similar to the THELMA (The Human Eye Learning Model Assistant described by the authors.1However, we feel that the use of simulation models alone is not enough to provide confidence and competency in direct ophthalmoscopy among medical students. The authors conclude that “constant training is a well-known strategy for skill enhancement”,1 and we have found that a lack of constant training in direct ophthalmoscopy is evident. After learning venepuncture, cannulation, and catheterization on the simulation models, we were able to observe doctors performing these skills before performing them on patients either in the wards or in theatre. These are skills that we are constantly trained in across a wide variety of medical and surgical attachments. However, opportunities to observe and practice ophthalmoscopy during our attachments are more limited, and thus we are not continuing to use the skills we learn.Authors' replyLucas Holderegger Ricci,1 Caroline Amaral Ferraz21Department of Ophthalmology, School of Medicine, Laureate

  7. Directed Assembly of Gold Nanoparticles

    DEFF Research Database (Denmark)

    Westerlund, Axel Rune Fredrik; Bjørnholm, Thomas

    2009-01-01

    As a complement to common "top-down" lithography techniques, "bottom-up" assembly techniques are emerging as promising tools to build nanoscale structures in a predictable way. Gold nanoparticles that are stable and relatively easy to synthesize are important building blocks in many such structures...... due to their useful optical and electronic properties. Programmed assembly of gold nanoparticles in one, two, and three dimensions is therefore of large interest. This review focuses on the progress from the last three years in the field of directed gold nanoparticle and nanorod assembly using...

  8. Analysis of Nonlinear Directional Couplers

    Institute of Scientific and Technical Information of China (English)

    M. Liu P. Shum; N. Q. Ngo

    2003-01-01

    @@ 1 Introduction Since the coupled-mode theory in cylindrical optical-fiber systems was proposed in 1972, the optical coupling between parallel optical waveguides has been a matter of scientific concern. Two-core fiber couplers, especially, have been studied extensively since the success of producing a two-core fiber functioning as a directional coupler in 1980. The wavelength and polarization selectivity of two-core fibers can find many applications. The nonlinear properties of the two-core fiber coupler were also inspected with the realization of an ultrafast all-optical switch.

  9. Direct Bonded Pontic (Laporan Kasus

    Directory of Open Access Journals (Sweden)

    Suhandi Sidjaja

    2015-10-01

    Full Text Available Advanced science and technology in dentistry enable dental practitioners to modified she bonding techniques in tooth replacement. A pontic made of composite resin bonded to etched enamel of the adjacent teeth can be used in the replacement of one missing anterior tooth with a virgin or sowed adpicent tooth. The advantages of this technique include a one visit treatment, cow cost, good esthetics, less side effects and easy repair or rebounding. Clinical evaluation showed a high success rate therefore with a proper diagnosis and a perfect skill of the direct bonded technique this treatment can be used as an alternative restoration.

  10. Directional Solidification of Eutectic Ceramics

    Science.gov (United States)

    Sayir, Ali

    2001-01-01

    Two major problems associated with structural ceramics are lack of damage tolerance and insufficient strength and creep resistance at very high temperatures of interest for aerospace application. This work demonstrated that the directionally solidified eutectics can have unique poly-phase microstructures and mechanical properties superior to either constituent alone. The constraining effect of unique eutectic microstructures result in higher resistance to slow crack growth and creep. Prospect of achieving superior properties through controlled solidification are presented and this technology can also be beneficial to produce new class of materials.

  11. Multi-directional local search.

    Science.gov (United States)

    Tricoire, Fabien

    2012-12-01

    This paper introduces multi-directional local search, a metaheuristic for multi-objective optimization. We first motivate the method and present an algorithmic framework for it. We then apply it to several known multi-objective problems such as the multi-objective multi-dimensional knapsack problem, the bi-objective set packing problem and the bi-objective orienteering problem. Experimental results show that our method systematically provides solution sets of comparable quality with state-of-the-art methods applied to benchmark instances of these problems, within reasonable CPU effort. We conclude that the proposed algorithmic framework is a viable option when solving multi-objective optimization problems.

  12. Neurolaw and Direct Brain Interventions

    OpenAIRE

    Vincent, N.A.

    2012-01-01

    This issue of Criminal Law and Philosophy contains three papers on a topic of increasing importance within the field of ‘‘neurolaw’’—namely, the implications for criminal law of direct brain intervention based mind altering techniques (DBI’s). To locate these papers’ topic within a broader context, I begin with an overview of some prominent topics in the field of neurolaw, where possible providing some references to relevant literature. The specific questions asked by the three authors, as we...

  13. Direct measurements of neutrino masses

    Energy Technology Data Exchange (ETDEWEB)

    Holzschuh, E. [Zurich Univ. (Switzerland). Inst. fuer Physik

    1996-11-01

    The direct measurements have so far given no indication for a nonzero (positive) mass of any of the three known neutrinos. The experiments measuring the tau and the muon neutrino are good shape. The tritium experiments are in an unfortunate situation. It is unclear to me whether the problems are experimental or theoretical or a combination of both. The electronic final states distribution have been calculated, but the results have never been tested experimentally. The most important question to be answered is about the validity of the sudden approximation. (author) 9 figs., 2 tabs., 16 refs.

  14. Future direction in airline marketing

    Science.gov (United States)

    Colussy, D. A.

    1972-01-01

    The rapid growth and broadening of the air travel market, coupled with a more sophisticated consumer, will dramatically change airline marketing over the next decade. Discussed is the direction this change is likely to take and its implications for companies within the industry. New conceptualization approaches are required if the full potential of this expanding market is to be fully realized. Marketing strategies are developed that will enable various elements of the travel industry to compete not only against each other but also with other products that are competing for the consumer's discretionary income.

  15. Accurate determination of antenna directivity

    DEFF Research Database (Denmark)

    Dich, Mikael

    1997-01-01

    The derivation of a formula for accurate estimation of the total radiated power from a transmitting antenna for which the radiated power density is known in a finite number of points on the far-field sphere is presented. The main application of the formula is determination of directivity from power......-pattern measurements. The derivation is based on the theory of spherical wave expansion of electromagnetic fields, which also establishes a simple criterion for the required number of samples of the power density. An array antenna consisting of Hertzian dipoles is used to test the accuracy and rate of convergence...

  16. Broadband direct RF digitization receivers

    CERN Document Server

    Jamin, Olivier

    2014-01-01

    This book discusses the trade-offs involved in designing direct RF digitization receivers for the radio frequency and digital signal processing domains.  A system-level framework is developed, quantifying the relevant impairments of the signal processing chain, through a comprehensive system-level analysis.  Special focus is given to noise analysis (thermal noise, quantization noise, saturation noise, signal-dependent noise), broadband non-linear distortion analysis, including the impact of the sampling strategy (low-pass, band-pass), analysis of time-interleaved ADC channel mismatches, sampling clock purity and digital channel selection. The system-level framework described is applied to the design of a cable multi-channel RF direct digitization receiver. An optimum RF signal conditioning, and some algorithms (automatic gain control loop, RF front-end amplitude equalization control loop) are used to relax the requirements of a 2.7GHz 11-bit ADC. A two-chip implementation is presented, using BiCMOS and 65nm...

  17. Overview: developmental toxicology: new directions.

    Science.gov (United States)

    Shuey, Dana; Kim, James H

    2011-10-01

    Since regulatory agencies began implementing the use of standardized developmental toxicology protocols in the mid-1960s, our knowledge base of embryo-fetal development and technologies for experimentation has grown exponentially. These developmental toxicology protocols were a direct result of the thalidomide tragedy from earlier that decade, when large numbers of women were exposed to the drug and over 10,000 cases of phocomelia resulted. In preventing a recurrence of such tragedies, the testing protocols are immensely successful and the field of toxicology has been dedicated to using them to advance safety and risk assessment of chemicals and pharmaceuticals. Recently, our perspectives on toxicity testing have been challenged by a growing awareness that while we have excelled in hazard identification, we are in dire need of improved methodologies for human health risk assessment, particularly with respect to the large numbers of environmental chemicals for which we have little toxicology data and to the growing sentiment that better alternatives to whole animals tests are needed. To provide a forum for scientists, researchers, and regulators, the Developmental and Reproductive Toxicology Technical Committee of the Health and Environmental Sciences Institute organized a 2-day workshop titled "Developmental Toxicology-New Directions" to evaluate lessons learned over the past 30 years and discuss the future of toxicology testing. The following four articles describe different presentations and discussions that were held over the course of those 2 days.

  18. Current Direct Neutrino Mass Experiments

    Directory of Open Access Journals (Sweden)

    G. Drexlin

    2013-01-01

    Full Text Available In this contribution, we review the status and perspectives of direct neutrino mass experiments, which investigate the kinematics of β-decays of specific isotopes (3H, 187Re, 163Ho to derive model-independent information on the averaged electron (antineutrino mass. After discussing the kinematics of β-decay and the determination of the neutrino mass, we give a brief overview of past neutrino mass measurements (SN1987a-ToF studies, Mainz and Troitsk experiments for 3H, cryobolometers for 187Re. We then describe the Karlsruhe Tritium Neutrino (KATRIN experiment currently under construction at Karlsruhe Institute of Technology, which will use the MAC-E-Filter principle to push the sensitivity down to a value of 200 meV (90% C.L.. To do so, many technological challenges have to be solved related to source intensity and stability, as well as precision energy analysis and low background rate close to the kinematic endpoint of tritium β-decay at 18.6 keV. We then review new approaches such as the MARE, ECHO, and Project8 experiments, which offer the promise to perform an independent measurement of the neutrino mass in the sub-eV region. Altogether, the novel methods developed in direct neutrino mass experiments will provide vital information on the absolute mass scale of neutrinos.

  19. Direct methods in protein crystallography.

    Science.gov (United States)

    Karle, J

    1989-11-01

    It is pointed out that the 'direct methods' of phase determination for small-structure crystallography do not have immediate applicability to macromolecular structures. The term 'direct methods in macromolecular crystallography' is suggested to categorize a spectrum of approaches to macromolecular structure determination in which the analyses are characterized by the use of two-phase and higher-order-phase invariants. The evaluation of the invariants is generally obtained by the use of heavy-atom techniques. The results of a number of the more recent algebraic and probabilistic studies involving isomorphous replacement and anomalous dispersion thus become valid subjects for discussion here. These studies are described and suggestions are also presented concerning future applicability. Additional discussion concerns the special techniques of filtering, the use of non-crystallographic symmetry, some features of maximum entropy and attempts to apply phase-determining formulas to the refinement of macromolecular structure. It is noted that, in addition to the continuing remarkable progress in macromolecular crystallography based on the traditional applications of isomorphous replacement and anomalous dispersion, recent valuable advances have been made in the application of non-crystallographic symmetry, in particular, to virus structures and in applications of filtering. Good progress has also been reported in the application of exact linear algebra to multiple-wavelength anomalous-dispersion investigations of structures containing anomalous scatterers of only moderate scattering power.

  20. On Making Directed Graphs Eulerian

    CERN Document Server

    Sorge, Manuel

    2011-01-01

    A directed graph is called Eulerian, if it contains a walk that traverses every arc in the graph exactly once. We study the problem of Eulerian Extension (EE) where a directed multigraph G and a weight function is given and it is asked whether G can be made Eulerian by adding arcs whose total weight does not exceed a given threshold. This problem is motivated through applications in vehicle routing and flowshop scheduling. However, EE is NP- hard and thus we use the parameterized complexity framework to analyze it. In parameterized complexity, the running time of algorithms is considered not only with respect to input length, but also with respect to other properties of the input-called "parameters". Dorn et al. proved that EE can be solved in O(4^k n^4) time, where k denotes the parameter "number of arcs that have to be added". In this thesis, we analyze EE with respect to the (smaller) parameters "number c of connected components in the input graph" and "sum b over indeg(v) - outdeg(v) for all vertices v in...

  1. Radial lean direct injection burner

    Science.gov (United States)

    Khan, Abdul Rafey; Kraemer, Gilbert Otto; Stevenson, Christian Xavier

    2012-09-04

    A burner for use in a gas turbine engine includes a burner tube having an inlet end and an outlet end; a plurality of air passages extending axially in the burner tube configured to convey air flows from the inlet end to the outlet end; a plurality of fuel passages extending axially along the burner tube and spaced around the plurality of air passage configured to convey fuel from the inlet end to the outlet end; and a radial air swirler provided at the outlet end configured to direct the air flows radially toward the outlet end and impart swirl to the air flows. The radial air swirler includes a plurality of vanes to direct and swirl the air flows and an end plate. The end plate includes a plurality of fuel injection holes to inject the fuel radially into the swirling air flows. A method of mixing air and fuel in a burner of a gas turbine is also provided. The burner includes a burner tube including an inlet end, an outlet end, a plurality of axial air passages, and a plurality of axial fuel passages. The method includes introducing an air flow into the air passages at the inlet end; introducing a fuel into fuel passages; swirling the air flow at the outlet end; and radially injecting the fuel into the swirling air flow.

  2. [Neurons that encode sound direction].

    Science.gov (United States)

    Peña, J L

    In the auditory system, the inner ear breaks down complex signals into their spectral components, and encodes the amplitude and phase of each. In order to infer sound direction in space, a computation on each frequency component of the sound must be performed. Space specific neurons in the owl s inferior colliculus respond only to sounds coming from a particular direction and represent the results of this computation. The interaural time difference (ITD) and interaural level difference (ILD define the auditory space for the owl and are processed in separate neural pathways. The parallel pathways that process these cues merge in the external nucleus of the inferior colliculus where the space specific neurons are selective to combinations of ITD and ILD. How do inputs from the two sources interact to produce combination selectivity to ITD ILD pairs? A multiplication of postsynaptic potentials tuned to ITD and ILD can account for the subthreshold responses of these neurons to ITD ILD pairs. Examples of multiplication by neurons or neural circuits are scarce, but many computational models assume the existence of this basic operation. The owl s auditory system uses such operation to create a 2 dimensional map of auditory space. The map of space in the owl s auditory system shows important similarities with representations of space in the cerebral cortex and other sensory systems. In encoding space or other stimulus features, individual neurons appear to possess analogous functional properties related to the synthesis of high order receptive fields.

  3. UROLOGIC ROBOTS AND FUTURE DIRECTIONS

    Science.gov (United States)

    Mozer, Pierre; Troccaz, Jocelyne; Stoianovici, Dan

    2009-01-01

    Purpose of review Robot-assisted laparoscopic surgery in urology has gained immense popularity with the Da Vinci system but a lot of research teams are working on new robots. The purpose of this paper is to review current urologic robots and present future developments directions. Recent findings Future systems are expected to advance in two directions: improvements of remote manipulation robots and developments of image-guided robots. Summary The final goal of robots is to allow safer and more homogeneous outcomes with less variability of surgeon performance, as well as new tools to perform tasks based on medical transcutaneous imaging, in a less invasive way, at lower costs. It is expected that improvements for remote system could be augmented reality, haptic feed back, size reduction and development of new tools for NOTES surgery. The paradigm of image-guided robots is close to a clinical availability and the most advanced robots are presented with end-user technical assessments. It is also notable that the potential of robots lies much further ahead than the accomplishments of the daVinci system. The integration of imaging with robotics holds a substantial promise, because this can accomplish tasks otherwise impossible. Image guided robots have the potential to offer a paradigm shift. PMID:19057227

  4. Urologic robots and future directions

    CERN Document Server

    Mozer, Pierre; Stoianovici, Dan; 10.1097/MOU.0b013e32831cc1ba

    2008-01-01

    PURPOSE OF REVIEW: Robot-assisted laparoscopic surgery in urology has gained immense popularity with the daVinci system, but a lot of research teams are working on new robots. The purpose of this study is to review current urologic robots and present future development directions. RECENT FINDINGS: Future systems are expected to advance in two directions: improvements of remote manipulation robots and developments of image-guided robots. SUMMARY: The final goal of robots is to allow safer and more homogeneous outcomes with less variability of surgeon performance, as well as new tools to perform tasks on the basis of medical transcutaneous imaging, in a less invasive way, at lower costs. It is expected that improvements for a remote system could be augmented in reality, with haptic feedback, size reduction, and development of new tools for natural orifice translumenal endoscopic surgery. The paradigm of image-guided robots is close to clinical availability and the most advanced robots are presented with end-use...

  5. 75 FR 53611 - Direct Investment Surveys: BE-577, Quarterly Survey of U.S. Direct Investment Abroad-Direct...

    Science.gov (United States)

    2010-09-01

    ... 15 CFR Part 806 [Docket No. 100202061-0063-01] RIN 0691-AA75 Direct Investment Surveys: BE-577, Quarterly Survey of U.S. Direct Investment Abroad--Direct Transactions of U.S. Reporter With Foreign.... Direct Investment Abroad--Transactions of U.S. Reporter With Foreign Affiliate.'' The exemption level...

  6. 75 FR 76630 - Direct Investment Surveys: BE-577, Quarterly Survey of U.S. Direct Investment Abroad-Direct...

    Science.gov (United States)

    2010-12-09

    ... Bureau of Economic Analysis 15 CFR Part 806 RIN 0691--AA75 Direct Investment Surveys: BE-577, Quarterly Survey of U.S. Direct Investment Abroad--Direct Transactions of U.S. Reporter With Foreign Affiliate... requirements for BE-577 quarterly survey of U.S. direct investment abroad. BEA conducts the survey...

  7. Boltzmann, Darwin and Directionality theory

    Science.gov (United States)

    Demetrius, Lloyd A.

    2013-09-01

    Boltzmann’s statistical thermodynamics is a mathematical theory which relates the macroscopic properties of aggregates of interacting molecules with the laws of their interaction. The theory is based on the concept thermodynamic entropy, a statistical measure of the extent to which energy is spread throughout macroscopic matter. Macroscopic evolution of material aggregates is quantitatively explained in terms of the principle: Thermodynamic entropy increases as the composition of the aggregate changes under molecular collision. Darwin’s theory of evolution is a qualitative theory of the origin of species and the adaptation of populations to their environment. A central concept in the theory is fitness, a qualitative measure of the capacity of an organism to contribute to the ancestry of future generations. Macroscopic evolution of populations of living organisms can be qualitatively explained in terms of a neo-Darwinian principle: Fitness increases as the composition of the population changes under variation and natural selection. Directionality theory is a quantitative model of the Darwinian argument of evolution by variation and selection. This mathematical theory is based on the concept evolutionary entropy, a statistical measure which describes the rate at which an organism appropriates energy from the environment and reinvests this energy into survivorship and reproduction. According to directionality theory, microevolutionary dynamics, that is evolution by mutation and natural selection, can be quantitatively explained in terms of a directionality principle: Evolutionary entropy increases when the resources are diverse and of constant abundance; but decreases when the resource is singular and of variable abundance. This report reviews the analytical and empirical support for directionality theory, and invokes the microevolutionary dynamics of variation and selection to delineate the principles which govern macroevolutionary dynamics of speciation and

  8. Note: Direct piezoelectric effect microscopy.

    Science.gov (United States)

    Mori, T J A; Stamenov, P; Dorneles, L S

    2015-07-01

    An alternative method for investigating piezoelectric surfaces is suggested, exploiting the direct piezoeffect. The technique relies on acoustic (ultrasonic) excitation of the imaged surface and mapping of the resulting oscillatory electric potential. The main advantages arise from the spatial resolution of the conductive scanning probe microscopy in combination with the relatively large magnitude of the forward piezo signal Upf, which can be of the order of tens of mV even for non-ferroelectric piezoelectric materials. The potency of this experimental strategy is illustrated with measurements on well-crystallized quartz surfaces, where Upf ∼ 50 mV, for a piezoelectric coefficient of d33 = - 2.27  ×  10(-12) m/V, and applied stress of about T3 ∼ 5.7 kPa.

  9. Direct Approach to Quantum Tunneling

    Science.gov (United States)

    Andreassen, Anders; Farhi, David; Frost, William; Schwartz, Matthew D.

    2016-12-01

    The decay rates of quasistable states in quantum field theories are usually calculated using instanton methods. Standard derivations of these methods rely in a crucial way upon deformations and analytic continuations of the physical potential and on the saddle-point approximation. While the resulting procedure can be checked against other semiclassical approaches in some one-dimensional cases, it is challenging to trace the role of the relevant physical scales, and any intuitive handle on the precision of the approximations involved is at best obscure. In this Letter, we use a physical definition of the tunneling probability to derive a formula for the decay rate in both quantum mechanics and quantum field theory directly from the Minkowski path integral, without reference to unphysical deformations of the potential. There are numerous benefits to this approach, from nonperturbative applications to precision calculations and aesthetic simplicity.

  10. Direct search for light gluinos

    CERN Document Server

    Fanti, V; Musa, L; Marras, D; Nappi, A; Hay, B; Moore, R W; Moore, K N; Munday, D J; Needham, M D; Parker, M A; White, T O; Wotton, S A; Andersen, J; Barr, Giles David; Bocquet, G; Bremer, J; Ceccucci, Augusto; Cundy, Donald C; Doble, Niels T; Fischer, G; Funk, W; Gatignon, L; Gianoli, A; Gonidec, A; Govi, G; Grafström, P; Kubischta, Werner; Luitz, S; Kesseler, G; Matheys, J P; Norton, Alan Robert; Palestini, S; Panzer-Steindel, B; Schinzel, D; Taureg, Hans; Velasco, M; Vossnack, O; Wahl, H; Wirrer, G; Kekelidze, V D; Mestvirishvili, A; Potrebenikov, Yu K; Tatishvili, G T; Tkachev, A L; Zinchenko, A I; Boyle, O; Martin, V J; Knowles, I G; Parsons, H; Dalpiaz, Pietro; Duclos, J; Frabetti, P L; Martini, M; Petrucci, F; Porcu, M; Savrié, M; Bizzeti, A; Calvetti, M; Graziani, G; Iacopini, E; Lenti, M; Michetti, A; Becker, H G; Blümer, H; Buchholz, P; Coward, D H; Ebersberger, C; Fox, H; Kalter, A; Kleinknecht, K; Koch, U; Köpke, L; Renk, B; Scheidt, J; Schmidt, J; Schönharting, V; Schué, Yu; Wilhelm, R; Winharting, A; Wittgen, M; Chollet, J C; Crépé, S; Iconomidou-Fayard, L; Fayard, Louis; Ocariz, J; Unal, G; Vattolo, D; Wingerter-Seez, I; Anzivino, Giuseppina; Cenci, P; Lubrano, P; Pepé, M; Gorini, B; Calafiura, P; Carosi, R; Cerri, C; Cirilli, M; Costantini, F; Fantechi, R; Giudici, Sergio; Mannelli, I; Marzulli, V M; Pierazzini, G M; Sozzi, M; Chèze, J B; Cogan, J; De Beer, M; Debu, P; Formica, A; Granier de Cassagnac, R; Khristov, P Z; Mazzucato, E; Peyaud, B; Schanne, S; Turlay, René; Vallage, B; Augustin, I; Bender, M; Holder, M; Ziolkowski, M; Arcidiacono, R; Biino, C; Marchetto, F; Menichetti, E; Nassalski, J P; Rondio, Ewa; Szleper, M; Wislicki, W; Wronka, S; Dibon, Heinz; Jeitler, Manfred; Markytan, Manfred; Mikulec, I; Neuhofer, Günther; Pernicka, Manfred; Taurok, Anton

    1999-01-01

    We present the results for a direct search for light gluinos through the appearance of $\\eta\\rightarrow 3\\pin$ with high transverse momentum in the vacuum tank of the NA48 experiment at CERN. We find one event within a lifetime range of $10^{-9}-10^{-3}$\\,s and another one between $10^{-10}-10^{-9}$\\,s. Both events are consistent with the expected background from neutrons in the beam, produced by 450 GeV protons impinging on the Be targets, which interact with the residual air in the tank. From these data we give limits on the production of the hypothetical $g\\widetilde{g}$ bound state, the $R^0$ hadron, and its $R^0\\rightarrow\\eta\\photino$ decay in the $R^0$ mass range between 1 and 5~GeV.

  11. Direct Search in Conceptual Design

    Directory of Open Access Journals (Sweden)

    E. B. Skvortsov

    2000-01-01

    Full Text Available The notion Concept implies a set of rules and ideas combining in a common intention actual principles for application, structure and form of a future artificial object. A rational concept is considered as a product of "conceptual design", which is nothing more than a step-by-step research on the possibility of achieving a desired goal. It precedes a full-scale development oriented to the project implementation. The author studies conceptual design as the process of idea evolution involving several s tages (Fig. 1. One of them is considered, for which an effort is made to generate an effective methodology of direct search for a rational concept with due regard for system and other methods.

  12. Directed actin assembly and motility.

    Science.gov (United States)

    Boujemaa-Paterski, Rajaa; Galland, Rémi; Suarez, Cristian; Guérin, Christophe; Théry, Manuel; Blanchoin, Laurent

    2014-01-01

    The actin cytoskeleton is a key component of the cellular architecture. However, understanding actin organization and dynamics in vivo is a complex challenge. Reconstitution of actin structures in vitro, in simplified media, allows one to pinpoint the cellular biochemical components and their molecular interactions underlying the architecture and dynamics of the actin network. Previously, little was known about the extent to which geometrical constraints influence the dynamic ultrastructure of these networks. Therefore, in order to study the balance between biochemical and geometrical control of complex actin organization, we used the innovative methodologies of UV and laser patterning to design a wide repertoire of nucleation geometries from which we assembled branched actin networks. Using these methods, we were able to reconstitute complex actin network organizations, closely related to cellular architecture, to precisely direct and control their 3D connections. This methodology mimics the actin networks encountered in cells and can serve in the fabrication of innovative bioinspired systems.

  13. New Directions In Professional Development

    Directory of Open Access Journals (Sweden)

    Rebecca Novick

    1996-08-01

    Full Text Available There is increasing recognition that school reform and staff development are integrally related. Yet, despite a rich literature on adult learning and human development which supports teachers' need for a wide array of opportunities to construct their own understandings and theories in a collaborative setting, top down mandates have frequently left teachers out of the reform process. It is argued here that effective staff development should be tied directly to the daily life of classroom and grounded in the questions and concerns of teachers. Both a theory of pedagogy that advocates teaching for understanding and learning as understanding and a model of staff development based on practical knowledge enriched by critical reflection are discussed.

  14. Direction Cryptography in Quantum Communications

    CERN Document Server

    Simmons, W; Simmons, Walter; Pakvasa, Sandip

    2003-01-01

    We examine a situation in which an information-carrying signal is sent from two sources to a common receiver. The radiation travels through free space in the presence of noise. The information resides in a relationship between the two beams. We inquire into whether itis possible, in principle, that the locations of the transmitters can be concealed from a party who receives the radiation and decodes the information. Direction finding entails making a set of measurements on asignal and constructing an analytic continuation of the time dependent fields from the results. The fact that this process is generally different in quantum mechanics and in classical electrodynamics is the basis in this investigation. We develop a model based upon encoding information into a microscopic, transverse, non-local quantum image (whose dimensions are of the order of a few wavelengths) and using a detector of a type recently proposed by Strekalov et al. The optical system, which uses SPDC (Spontaneous Parametric Down Conversion)...

  15. GLOBALIZATION AND FOREIGN DIRECT INVESTMENTS

    Directory of Open Access Journals (Sweden)

    Elena Chirilă – Donciu

    2013-07-01

    Full Text Available Mobilizing financial resources to cover investment needs is a concern of all countries, developed or developing ones, of consolidated market economies or emerging ones. A distinctive characteristic of Global Economy over the last few decades has been the rising rate and impressive increase in Foreign Direct Investment (FDI. The purpose of this research is to analyse global FDI inflows in Europe and in Romania. The results of the research support the idea that the balance of economic power is changing in the world economy and the countries that own a stable and solid industrial base are at an advantage. The new trends determined by the economic crisis in the field of FDI refer to the growing percentage of developing and emerging countries in the global flows of FDI.

  16. Conflict-Directed Backjumping Revisited

    CERN Document Server

    Chen, X; 10.1613/jair.788

    2011-01-01

    In recent years, many improvements to backtracking algorithms for solving constraint satisfaction problems have been proposed. The techniques for improving backtracking algorithms can be conveniently classified as look-ahead schemes and look-back schemes. Unfortunately, look-ahead and look-back schemes are not entirely orthogonal as it has been observed empirically that the enhancement of look-ahead techniques is sometimes counterproductive to the effects of look-back techniques. In this paper, we focus on the relationship between the two most important look-ahead techniques---using a variable ordering heuristic and maintaining a level of local consistency during the backtracking search---and the look-back technique of conflict-directed backjumping (CBJ). We show that there exists a "perfect" dynamic variable ordering such that CBJ becomes redundant. We also show theoretically that as the level of local consistency that is maintained in the backtracking search is increased, the less that backjumping will be a...

  17. Probabilistic direct counterfactual quantum communication

    Science.gov (United States)

    Zhang, Sheng

    2017-02-01

    It is striking that the quantum Zeno effect can be used to launch a direct counterfactual communication between two spatially separated parties, Alice and Bob. So far, existing protocols of this type only provide a deterministic counterfactual communication service. However, this counterfactuality should be payed at a price. Firstly, the transmission time is much longer than a classical transmission costs. Secondly, the chained-cycle structure makes them more sensitive to channel noises. Here, we extend the idea of counterfactual communication, and present a probabilistic-counterfactual quantum communication protocol, which is proved to have advantages over the deterministic ones. Moreover, the presented protocol could evolve to a deterministic one solely by adjusting the parameters of the beam splitters. Project supported by the National Natural Science Foundation of China (Grant No. 61300203).

  18. Directional dependence of binaural loudness

    DEFF Research Database (Denmark)

    Ellermeier, Wolfgang; Sivonen, Ville Pekka

    2006-01-01

    on binaural loudness summation, on the other hand, focuses on a highly artificial paradigm according to which unnatural combinations of sound pressure levels(such as monotic-diotic comparisons) are presented to listeners via headphones. In order to reconcile these two approaches, we recently started a series...... incidence angle, in order to relate the changes in actual at-ear exposure to the observed changes in loudness as a function of sound incidence. Combining the listening-test data with the physical measurements, an attempt was made to model the binaural summation underlying the directional loudness matches.......Even though there is a vast body of literature on spatial hearing, little is known on how the location of a sound source affects its loudness. The pertinent research on head-related transfer functions(HRTFs) primarily deals with issues of localization and spatial discriminability. The literature...

  19. The SPES direct UCx target

    Science.gov (United States)

    Andrighetto, A.; Antonucci, C.; Barbui, M.; Carturan, S.; Cervellera, F.; Cevolani, S.; Cinausero, M.; Colombo, P.; Dainelli, A.; di Bernardo, P.; Gramegna, F.; Maggioni, G.; Meneghetti, G.; Petrovich, C.; Piga, L.; Prete, G.; Rizzi, V.; Tonezzer, M.; Zafiropoulos, D.; Zanonato, P.

    2007-11-01

    A possible solution for a target system aimed at the production of exotic nuclei as a result of high energy fissions in 238U compounds has been analyzed. The proposed configuration is constituted by a primary proton beam (40 MeV, 0.2 mA) directly impinging on uranium carbide disks inserted within a cylindrical carbon box. This system has been conceived to obtain both a high number of neutron rich atoms (originated from about 1013 fissions/s) and a low power deposition in the target. In order to extract the fission fragments, the box has to be hold at 2000○C. The thermal analysis shows the capability of the thermal radiation to cool the disks with a reasonable margin below the material melting point. Moreover, the analyses of the thermo-mechanical behaviour and of the effusion times confirm the promising features of this target configuration.

  20. Together in the same direction

    CERN Multimedia

    2013-01-01

    It’s sometimes difficult to explain the nature of global collaboration in particle physics: how fierce competition coexists with collaboration, and how, whatever our differences, we all pull in the same direction. But this week gave us two strong examples.   Firstly, on Wednesday, the Technical Design Report (TDR) for the International Linear Collider (ILC) was officially delivered to the International Committee for Future Accelerators, ICFA, the global body that oversees the development of major projects in particle physics. This event marks the culmination of years of effort through close global collaboration between labs around the world. It has seen tough collective decisions being taken between competing technologies, with all participating labs lining up behind the chosen option. And on Wednesday this week, it saw the linear collider community choosing CERN as one of the three venues for the official handover, despite the fact that CERN was not one of the original core labs ...

  1. The Search for Directed Intelligence

    CERN Document Server

    Lubin, Philip

    2016-01-01

    We propose a search for sources of directed energy systems such as those now becoming technologically feasible on Earth. Recent advances in our own abilities allow us to foresee our own capability that will radically change our ability to broadcast our presence. We show that systems of this type have the ability to be detected at vast distances and indeed can be detected across the entire horizon. This profoundly changes the possibilities for searches for extra-terrestrial technology advanced civilizations. We show that even modest searches can be extremely effective at detecting or limiting many civilization classes. We propose a search strategy that will observe more than 10 12 stellar and planetary systems with possible extensions to more than 10 20 systems allowing us to test the hypothesis that other similarly or more advanced civilization with this same capability, and are broadcasting, exist.

  2. New directions in hospital governance.

    Science.gov (United States)

    Shortell, S M

    1989-01-01

    This article suggests new directions for hospital governance to meet the demands of a rapidly changing health care environment. Board members must increasingly play roles as risk takers, strategic directors, experts, mentors, and evaluators. Lessons from other industries regarding risk taking, use of expertise, and streamlining decision making must be adapted to meet hospital needs. Recent data suggest that these needs may still differ by hospital ownership despite a convergence in investor-owned and not-for-profit corporate structures. The effectiveness of hospital boards in the future will depend on their ability to: (1) manage a diverse group of stakeholders; (2) involve physicians in the management and governance process; (3) meet the governance needs of multi-institutional systems and hospital restructuring; (4) meet the challenges of diversification and vertical integration; and (5) understand strategy formulation and implementation as interdependent and interrelated processes.

  3. Development direction of energy resources

    Energy Technology Data Exchange (ETDEWEB)

    Hua, A. [China University of Mining and Technology, Xuzhou (China). College of Architecture and Civil Engineering

    2002-01-01

    According to the prediction of the developmental trend of the economy and population of the world, the mineral energy resource is faced with exhaustion. Exploitation and combustion of minerals are seriously polluting the environment. In addition, the production areas of mineral resources are not the energy consumption areas. Therefore, the energy resource of the world is at the stage of structural reorganisation. The exploitation and utilisation of green energy resources such as solar energy, wind energy, oceanic energy, geothermic energy, biologic energy and hydrogen in China are introduced briefly. The green energy resources have abundant reserves. Their utilisation is propitious to environment protection, and the relevant technique has come to a generalised stage. It is believed that green energy should be the developmental direction of energy resource and that the speciality of green energy ought to be set up in energy resources colleges to train the required personnel. 10 refs., 5 tabs.

  4. Direct lateral maneuvers in hawkmoths

    Directory of Open Access Journals (Sweden)

    Jeremy S. M. Greeter

    2016-01-01

    Full Text Available We used videography to investigate direct lateral maneuvers, i.e. ‘sideslips’, of the hawkmoth Manduca sexta. M. sexta sideslip by rolling their entire body and wings to reorient their net force vector. During sideslip they increase net aerodynamic force by flapping with greater amplitude, (in both wing elevation and sweep, allowing them to continue to support body weight while rolled. To execute the roll maneuver we observed in sideslips, they use an asymmetric wing stroke; increasing the pitch of the roll-contralateral wing pair, while decreasing that of the roll-ipsilateral pair. They also increase the wing sweep amplitude of, and decrease the elevation amplitude of, the contralateral wing pair relative to the ipsilateral pair. The roll maneuver unfolds in a stairstep manner, with orientation changing more during downstroke than upstroke. This is due to smaller upstroke wing pitch angle asymmetries as well as increased upstroke flapping counter-torque from left-right differences in global reference frame wing velocity about the moth's roll axis. Rolls are also opposed by stabilizing aerodynamic moments from lateral motion, such that rightward roll velocity will be opposed by rightward motion. Computational modeling using blade-element approaches confirm the plausibility of a causal linkage between the previously mentioned wing kinematics and roll/sideslip. Model results also predict high degrees of axial and lateral damping. On the time scale of whole and half wing strokes, left-right wing pair asymmetries directly relate to the first, but not second, derivative of roll. Collectively, these results strongly support a roll-based sideslip with a high degree of roll damping in M. sexta.

  5. Direct Vasodilators and Sympatholytic Agents.

    Science.gov (United States)

    McComb, Meghan N; Chao, James Y; Ng, Tien M H

    2016-01-01

    Direct vasodilators and sympatholytic agents were some of the first antihypertensive medications discovered and utilized in the past century. However, side effect profiles and the advent of newer antihypertensive drug classes have reduced the use of these agents in recent decades. Outcome data and large randomized trials supporting the efficacy of these medications are limited; however, in general the blood pressure-lowering effect of these agents has repeatedly been shown to be comparable to other more contemporary drug classes. Nevertheless, a landmark hypertension trial found a negative outcome with a doxazosin-based regimen compared to a chlorthalidone-based regimen, leading to the removal of α-1 adrenergic receptor blockers as first-line monotherapy from the hypertension guidelines. In contemporary practice, direct vasodilators and sympatholytic agents, particularly hydralazine and clonidine, are often utilized in refractory hypertension. Hydralazine and minoxidil may also be useful alternatives for patients with renal dysfunction, and both hydralazine and methyldopa are considered first line for the treatment of hypertension in pregnancy. Hydralazine has also found widespread use for the treatment of systolic heart failure in combination with isosorbide dinitrate (ISDN). The data to support use of this combination in African Americans with heart failure are particularly robust. Hydralazine with ISDN may also serve as an alternative for patients with an intolerance to angiotensin antagonists. Given these niche indications, vasodilators and sympatholytics are still useful in clinical practice; therefore, it is prudent to understand the existing data regarding efficacy and the safe use of these medications. © The Author(s) 2015.

  6. Invariance of directed spaces and persistence

    DEFF Research Database (Denmark)

    2006-01-01

    With motivations arising from concurrency theory within Computer Science, a new field of research, directed algebraic topology, has emerged. The main characteristic is, that it involves spaces of "directed paths'' (or timed paths, executions) in a "directed space''; these directed paths can be co...

  7. 40 CFR 73.72 - Direct sales.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Direct sales. 73.72 Section 73.72... ALLOWANCE SYSTEM Auctions, Direct Sales, and Independent Power Producers Written Guarantee § 73.72 Direct sales. Allowances that were formerly part of the direct sale program, which has been terminated...

  8. 14 CFR 212.7 - Direct sales.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Direct sales. 212.7 Section 212.7... REGULATIONS CHARTER RULES FOR U.S. AND FOREIGN DIRECT AIR CARRIERS § 212.7 Direct sales. (a) Certificated and... direct sales Public Charters by a foreign air carrier upon a finding that such action is necessary in...

  9. Laterality and Directional Preferences in Preschool Children.

    Science.gov (United States)

    Tan, Lesley E.

    1982-01-01

    Directional preference for horizontal hand movements was investigated in 49 right- and 49 left-handed four-year-olds using three drawing tests. Directionality for more complex perceptual-motor tasks has a different basis than directionality for simple tasks; such directionality is established at a later age but only for the right hand. (Author/CM)

  10. Summary of European directives for explosion safety

    NARCIS (Netherlands)

    Versloot, N.H.A.; Klein, A.J.J.; Maaijer, M. de

    2008-01-01

    On July 1, 2003 a transitional period has ended and two European directives became fully active: • Directive 1999/92/EC • Directive 94/9/EC These directives have an impact on companies with an explosion hazard (gas, vapor, mist, or dust explosions) and on manufacturers of equipment intended to be

  11. Invariance of directed spaces and persistence

    DEFF Research Database (Denmark)

    2006-01-01

    With motivations arising from concurrency theory within Computer Science, a new field of research, directed algebraic topology, has emerged. The main characteristic is, that it involves spaces of "directed paths'' (or timed paths, executions) in a "directed space''; these directed paths can...

  12. Mental health literacy towards depression among non-medical students at a Malaysian university.

    Science.gov (United States)

    Khan, Tahir M; Sulaiman, Syed A; Hassali, Mohamed A

    2010-03-01

    Background The aim of the present study was to evaluate the knowledge and perception of depression among students of University Sains Malaysia (USM), in Penang, Peninsular Malaysia.Method Face-to-face interviews were conducted using a pre-validated 21-item questionnaire among students at USM.Results A total of 500 respondents participated in the survey comprising 24.6% (n=123) males and 75.4% (n=377) females. Half (50.0%, n=250) were Malays, followed by Chinese (44.0%, n=220) and Indians (6.0%, n=30). Whilst exploring the respondents' knowledge of the symptoms of depression, it was found that Chinese females had a comparatively better knowledge (P=0.058) of the symptoms of depression in comparison with Malays and Indians. Overall, social issues were attributed as the possible cause of depression. A cursory knowledge level was observed regarding medication for depression. Female students were more inclined towards the use of alternative and traditional medicines. However, with regard to seeking professional help, consultation with a psychiatrist was preferred by the majority.Conclusion Overall, a moderate level of knowledge about the symptoms of depression and a cursory knowledge of its therapy were observed. Those with personal experience of depression had better knowledge of the symptoms and therapy. Alternative treatments and traditional medicines were also favoured. There is a risk that this may affect the ability of Malaysian youths to seek evidence-based mental health care.

  13. Use of antibiotics among non-medical students in a Nigerian university

    African Journals Online (AJOL)

    EB

    long duration of treatment (70; 17.5%), side effects experienced (60;15.0%), polypharmacy (56;14.0%), tablet size (45;11.3%), ... of respondents had no significant effect on respondents' knowledge or adherence (p>0.05). .... of “bad food”. Prevention .... A household survey in a Mexican community. ... Bulletin of World Health.

  14. Knowledge, Attitude and Practice between Medical and Non-Medical Sciences Students about Food Labeling

    Directory of Open Access Journals (Sweden)

    Aida Malek Mahdavi

    2012-12-01

    Full Text Available Background: Considering the significant role of consumers’ awareness about food labels in making healthy food choices, this study was designed to assess the knowledge, attitude and prac-tice of university students about food labeling.Methods: In this cross-sectional study, 332 students aged 18-25 yr in five different academic ma-jors (including Nutrition, Public Health, Health Services Administration, Paramedical and En-gineering were asked to complete an approved questionnaire contained fifteen questions. The chi-square test was applied to examine the differences across various major groups.Results: 89.2% of the students believed that food labels had effect on nutritional awareness. 77.4% were agreed with the usefulness of the food labels and 79.2% did not feel that nutrition claims on food label were truthful. For 84% of students, the expiry date and storage conditions information were the most important informational cues to appear on the food labels. From 47.6% of students who reported the use of nutrition facts label in their often or always shopping; only 32.3% used the information on labels to fit the food into their daily diet. Surprisingly, fatty acids were the least noteworthy items (1.9% on nutrition facts labels. Regarding students’ major, there was significant difference in their knowledge, attitude and practice about truth of the nutri-tion claims, using food labels and importance of health claims (P<0.05.Conclusion: Food labels were more useful tools for students and had an effect on their nutri-tional awareness. Designing and implementation of the educational programs in order to increase the level of knowledge about food labels is suggested.

  15. Non-medical applications of non invasive prenatal testing: ethical issues and apllicabilities

    OpenAIRE

    Tasinato, Paola

    2013-01-01

    The possibility of obtaining material for foetal molecular analysis without the need of invasive procedures has been a long wished improvement of practice in prenatal diagnostics. The demonstration of the presence of foetal cells and circulating foetal free-DNA in a sample of mother-to-be’s blood promised that a non-invasive approach for prenatal diagnostics is near to becoming a reality. The presence of foetal cells (albeit in low numbers) in maternal blood has been known since 1893, when...

  16. Use of 'non-medical' ultrasound imaging before mid-pregnancy in Copenhagen

    DEFF Research Database (Denmark)

    Thorup, Tine J; Zingenberg, Helle

    2015-01-01

    We have investigated prospectively how many pregnant women purchase ultrasound imaging before week 20, why they purchase scans, and which professional skills and certifications women expect the person performing the scan to have. In addition, we wanted to investigate whether the women were aware...... the fetal health and development checked and 49% wanted to find out the gender of the fetus. In addition, 68% felt that they received an evaluation of the fetal health state and 58% believed that there was legislation demanding a professional authorization needed to perform ultrasound imaging. This study...... shows that there is a significant demand among pregnant women for commercial ultrasound imaging of their fetus for various reasons. Knowledge of certifications and requirements for legal authorization is, however, sparse....

  17. Non-medical out-of-pocket expenses incurred by families during their child's hospitalization.

    Science.gov (United States)

    DiFazio, Rachel L; Vessey, Judith A

    2013-09-01

    Little is known about the nonmedical out of pocket expenses (NOOPEs) incurred by families of hospitalized children. The purpose of this study is to help nurses, other healthcare providers, hospital administrators, and policymakers better understand the NOOPEs incurred by families during their child's hospitalization. Parents of children (n = 50) who underwent orthopedic surgery at a major tertiary-care children's hospital reported all NOOPEs incurred during their child's hospitalization. Descriptive statistics and univariate and multiple logistic regression analyses were used to analyze the data. The total NOOPEs ranged from $17.00 to $4745.00 (M = $736.21) per hospitalization, with 2096 missed hours from work. Length of stay, gross family income, distance from the hospital, and Hollingshead score are significant predictors of expenses (F-ratio = 732.88, p Hospitalization is associated with numerous NOOPEs. Future research needs to investigate the total array of expenses to families.

  18. Evaluation of the Cardiac Depression Visual Analogue Scale in a medical and non-medical sample.

    Science.gov (United States)

    Di Benedetto, Mirella; Sheehan, Matthew

    2014-01-01

    Comorbid depression and medical illness is associated with a number of adverse health outcomes such as lower medication adherence and higher rates of subsequent mortality. Reliable and valid psychological measures capable of detecting a range of depressive symptoms found in medical settings are needed. The Cardiac Depression Visual Analogue Scale (CDVAS) is a recently developed, brief six-item measure originally designed to assess the range and severity of depressive symptoms within a cardiac population. The current study aimed to further investigate the psychometric properties of the CDVAS in a general and medical sample. The sample consisted of 117 participants, whose mean age was 40.0 years (SD = 19.0, range 18-84). Participants completed the CDVAS, the Cardiac Depression Scale (CDS), the Depression Anxiety Stress Scales (DASS) and a demographic and health questionnaire. The CDVAS was found to have adequate internal reliability (α = .76), strong concurrent validity with the CDS (r = .89) and the depression sub-scale of the DASS (r = .70), strong discriminant validity and strong predictive validity. The principal components analysis revealed that the CDVAS measured only one component, providing further support for the construct validity of the scale. Results of the current study indicate that the CDVAS is a short, simple, valid and reliable measure of depressive symptoms suitable for use in a general and medical sample.

  19. [The social and medicolegal aspects of maternal request or non-medically indicated cesarean section].

    Science.gov (United States)

    Fisher, Menachem; Shrem, David; Solt, Ido

    2013-07-01

    Patient choice cesarean or cesarean by maternal request/ demand is a controversial issue. The medical literature contains evidence based data on the medical aspects of patient choice cesarean, risks and benefits to the mother and her newborn. Fewer studies focused on the social and legal aspects of patient choice cesarean. This opinion paper discusses the social and legal aspects of patient choice cesarean.

  20. [The history of antitobacco actions in the last 500 years. part. 1. Non-medical actions].

    Science.gov (United States)

    Grzybowski, Andrzej

    2006-01-01

    Tobacco was brought to Europe by Christopher Columbus, who discovered it in Cuba in October, 1492. Spread of tobacco consumption was initiated by the French diplomat Jean Nicot de Villemain, who in 1560 recommended it in the form of powdered tobacco leaves to the French Queen Catherine de Medice to combat her migraine headaches, and introduced the term Nicotiana tobaccum. Tobacco consumption greatly rose after the I World War, and after the II World War it became very common, especially among man. In the first half of the 20th century the sale of tobacco products rose by 61%, and cigarettes dominated the market of tobacco products. At the beginning of the 20th century cigarettes constituted only 2% of the total sale of tobacco products, while in the middle of the 20th century--more than 80%. Although the first epidemiological papers indicating that "smoking is connected with the shortening of life span" were published in the first half of the 20th century, not until 1950 did Hill and Doll in Great Britain, and Wynder and Graham in USA in 1951 show a statistically significant correlation between cigarettes smoking and lung cancer occurrence. Many controversies according the use of tobacco accompanied it from the beginning of its presence in Europe. The conflicting opinions according to its influence to health coexisted in the 16th to 19th centuries. In this period, especially in the 19th century dominated moral and religious arguments against tobacco. In the 20th century however, and particularly in its second part, development in medical research was enhanced by civil voluntary actions against advertisement and passive smoking. This lead to the significant limitation of tobacco expansion in Europe, USA and Canada in the end of the 20th century.

  1. Burden of out-of-pocket expenditure for road traffic injuries in urban India

    Directory of Open Access Journals (Sweden)

    Kumar G

    2012-08-01

    Full Text Available Abstract Background Road traffic injuries (RTI are an increasing public health problem in India where out-of-pocket (OOP expenditures on health are among the highest in the world. We estimated the OOP expenses for RTI in a large city in India. Methods Information on medical and non-medical expenditure was documented for RTI cases of all ages that reported alive or dead to the emergency departments of two public hospitals and a large private hospital in Hyderabad. Differential risk of catastrophic OOP total expenditure (COPE-T and medical expenditure (COPE-M, and distress financing was assessed for 723 RTI cases that arrived alive at the study hospitals with multiple logistic regression. Catastrophic expenditure was defined as expenditure > 25% of the RTI patient’s annual household income. Variation in intensity of COPE-M in RTI was assessed using multiple classification analysis (MCA. Results The median OOP medical and non-medical expenditure was USD 169 and USD 163, respectively. The prevalence of COPE-M and COPE-T was 21.9% (95% CI 18.8-24.9 and 46% (95% CI 42–49.3, respectively. Only 22% had access to medical insurance. Being admitted to a private hospital (OR 5.2, 95% CI 2.7–9.9 and not having access to insurance (OR 3.8, 95% CI 1.9–7.6 were significantly associated with risk of having COPE – M. Similar results were seen for COPE - T. MCA analysis showed that the burden of OOP medical expenditure was mainly associated with in-patient days in hospital (Eta =0.191. Prevalence of distress financing was 69% (95% CI 65.5-72.3 with it being significantly higher for those reporting to the public hospitals (OR 2.8, 95% CI 1.7-4.6, those belonging to the lowest per capita annual household income quartile (OR 7.0, 95% CI 3.7-13.3, and for those without insurance access (OR 3.4, 95% CI 2.0-5.7. Conclusions This paper has outlined the high burden of out-of-pocket medical and total expenditure associated with RTI in India. These data

  2. Why are Hydrogen Bonds Directional?

    Indian Academy of Sciences (India)

    ABHISHEK SHAHI; ELANGANNAN ARUNAN

    2016-10-01

    The recent IUPAC recommendation on the definition of hydrogen bonding points out that directionality is a defining characteristic of a hydrogen bond and the angle ∠X-H-Y is generally linear or 180◦. It also suggests that the X-H· · ·Y angle be greater than 110◦ for an interaction to be characterized as a hydrogenbond but does not provide any rationale for the same. This article reports a rationale for limiting the angle, based on the electron density topology using the quantum theory of atoms in molecules. Electron density topology for common hydrogen bond donors HF, HCl, HBr, HNC, HCN and HCCH are reported in this work. These calculations lead to an interesting observation that the atomic basins of H atom in all these donor molecules are limited justifying the restriction of hydrogen bond angle. Moreover, similar analysis on some hydrogen bonded complexes confirms that beyond this angle the acceptor atom Y starts interacting with the atomic basin on X. However, conclusions based on bond lengths and angles have to be treated with care and as the IUPAC recommendation points out that independent ‘evidence for bond formation’ in every case is important.

  3. Current Direct Neutrino Mass Experiments

    CERN Document Server

    Drexlin, G; Mertens, S; Weinheimer, C

    2013-01-01

    In this contribution we review the status and perspectives of direct neutrino mass experiments. These experiments investigate the kinematics of $\\beta$-decays of specific isotopes ($^3$H, $^{187}$Re, $^{163}$Ho) to derive model-independent information on the averaged electron (anti-) neutrino mass, which is formed by the incoherent sum of the neutrino mass eigenstates contributing to the electron neutrino. We first review the kinematics of $\\beta$-decay and the determination of the neutrino mass, before giving a brief overview of past neutrino mass measurements (SN1987a-ToF studies, Mainz and Troitsk experiments for $^3$H, cryo-bolometers for $^{187}$Re). We then describe the Karlsruhe Tritium Neutrino (KATRIN) experiment which is currently under construction at Karlsruhe Institute of Technology. The large-scale setup will use the MAC-E-Filter principle pioneered earlier to push the sensitivity down to a value of 200 meV(90% C.L.). KATRIN faces many technological challenges that have to be resolved with regar...

  4. Direct Model Checking Matrix Algorithm

    Institute of Scientific and Technical Information of China (English)

    Zhi-Hong Tao; Hans Kleine Büning; Li-Fu Wang

    2006-01-01

    During the last decade, Model Checking has proven its efficacy and power in circuit design, network protocol analysis and bug hunting. Recent research on automatic verification has shown that no single model-checking technique has the edge over all others in all application areas. So, it is very difficult to determine which technique is the most suitable for a given model. It is thus sensible to apply different techniques to the same model. However, this is a very tedious and time-consuming task, for each algorithm uses its own description language. Applying Model Checking in software design and verification has been proved very difficult. Software architectures (SA) are engineering artifacts that provide high-level and abstract descriptions of complex software systems. In this paper a Direct Model Checking (DMC) method based on Kripke Structure and Matrix Algorithm is provided. Combined and integrated with domain specific software architecture description languages (ADLs), DMC can be used for computing consistency and other critical properties.

  5. The direct aromatization of methane

    Energy Technology Data Exchange (ETDEWEB)

    Marcelin, G.; Oukaci, R.; Migone, R.A.; Kazi, A.M. [Altamira Instruments, Pittsburgh, PA (United States)

    1995-12-31

    The thermal decomposition of methane shows significant potential as a process for the production of higher unsaturated and aromatic hydrocarbons when the extent of the reaction is limited. Thermodynamic calculations have shown that when the reaction is limited to the formation of C{sub 2} to C{sub 10} products, yields of aromatics can exceed 40% at temperatures of 1200{degrees}C. Preliminary experiments have shown that when the reaction is limited to the formation of C{sub 2} to C{sub 10} products, yields of aromatics can exceed 40% at temperatures of 1200{degrees}C. Preliminary experiments have shown that cooling the product and reacting gases as the reaction proceeds can significantly reduce or eliminate the formation of solid carbon and heavier (C{sub 10+}) materials. Much work remains to be done in optimizing the quenching process and this is one of the goals of this program. Means to lower the temperature of the reaction are being studied as this result in a more feasible commercial process due to savings realized in energy and material of construction costs. The use of free-radical generators and catalysts will be investigated as a means of lowering the reaction temperature thus allowing faster quenching. It is highly likely that such studies will lead to a successful direct methane to higher hydrocarbon process.

  6. New directions for veterinary technology.

    Science.gov (United States)

    Chadderdon, Linda M; Lloyd, James W; Pazak, Helene E

    2014-01-01

    Veterinary technology has generally established itself well in companion-animal and mixed-animal veterinary medical practice, but the career's growth trajectory is uncertain. Michigan State University (MSU) convened a national conference, "Creating the Future of Veterinary Technology-A National Dialogue," in November 2011 to explore ways to elevate the veterinary technician/technologist's role in the veterinary medical profession and to identify new directions in which the career could expand. Veterinary technicians/technologists might advance their place in private practice by not only improving their clinical skills, but by also focusing on areas such as practice management, leadership training, business training, conflict resolution, information technology, and marketing/communications. Some new employment settings for veterinary technicians/technologists include more participation within laboratory animal medicine and research, the rural farm industry, regulatory medicine, and shelter medicine. Achieving these ends would call for new training options beyond the current 2-year and 4-year degree programs. Participants suggested specialty training programs, hybrid programs of various types, online programs, veterinary technician residency programs of 12-18 months, and more integration of veterinary technician/technology students and veterinary medicine students at colleges of veterinary medicine.

  7. Gravitational spectra from direct measurements

    Science.gov (United States)

    Wagner, C. A.; Colombo, O. L.

    1978-01-01

    A simple rapid method is described for determining the spectrum of a surface field from harmonic analysis of direct measurements along great circle arcs. The method is shown to give excellent overall trends to very high degree from even a few short arcs of satellite data. Three examples are taken with perfect measurements of satellite tracking over a planet made up of hundreds of point-masses using (1) altimetric heights from a low orbiting spacecraft, (2) velocity residuals between a low and a high satellite in circular orbits, and (3) range-rate data between a station at infinity and a satellite in highly eccentric orbit. In particular, the smoothed spectrum of the Earth's gravitational field is determined to about degree 400(50 km half wavelength) from 1 D x 1 D gravimetry and the equivalent of 11 revolutions of Geos 3 and Skylab altimetry. This measurement shows there is about 46 cm of geoid height remaining in the field beyond degree 180.

  8. Low backlash direct drive actuator

    Science.gov (United States)

    Kuklo, Thomas C.

    1994-01-01

    A low backlash direct drive actuator is described which comprises a motor such as a stepper motor having at least 200 steps per revolution; a two part hub assembly comprising a drive hub coaxially attached to the shaft of the motor and having a plurality of drive pins; a driven hub having a plurality of bores in one end thereof in alignment with the drive pins in the drive hub and a threaded shaft coaxially mounted in an opposite end of the driven hub; and a housing having a central bore therein into which are fitted the drive hub and driven hub, the housing having a motor mount on one end thereof to which is mounted the stepper motor, and a closed end portion with a threaded opening therein coaxial with the central bore in the housing and receiving therein the threaded shaft attached to the driven hub. Limit switches mounted to the housing cooperate with an enlarged lip on the driven hub to limit the lateral travel of the driven hub in the housing, which also acts to limit the lateral travel of the threaded shaft which functions as a lead screw.

  9. Direct anti-HCV agents

    Directory of Open Access Journals (Sweden)

    Xingquan Zhang

    2016-01-01

    Full Text Available Unlike human immunodeficiency virus (HIV and hepatitis B virus (HBV, hepatitis C virus (HCV infection is a curable disease. Current direct antiviral agent (DAA targets are focused on HCV NS3/4A protein (protease, NS5B protein (polymerase and NS5A protein. The first generation of DAAs includes boceprevir and telaprevir, which are protease inhibitors and were approved for clinical use in 2011. The cure rate for genotype 1 patients increased from 45% to 70% when boceprevir or telaprevir was added to standard PEG-IFN/ribavirin. More effective and less toxic second generation DAAs supplanted these drugs by 2013. The second generation of DAAs includes sofosbuvir (Sovaldi, simeprevir (Olysio, and fixed combination medicines Harvoni and Viekira Pak. These drugs increase cure rates to over 90% without the need for interferon and effectively treat all HCV genotypes. With these drugs the “cure HCV” goal has become a reality. Concerns remain about drug resistance mutations and the high cost of these drugs. The investigation of new HCV drugs is progressing rapidly; fixed dose combination medicines in phase III clinical trials include Viekirax, asunaprevir+daclatasvir+beclabuvir, grazoprevir+elbasvir and others.

  10. Future directions of electron crystallography.

    Science.gov (United States)

    Fujiyoshi, Yoshinori

    2013-01-01

    In biological science, there are still many interesting and fundamental yet difficult questions, such as those in neuroscience, remaining to be answered. Structural and functional studies of membrane proteins, which are key molecules of signal transduction in neural and other cells, are essential for understanding the molecular mechanisms of many fundamental biological processes. Technological and instrumental advancements of electron microscopy have facilitated comprehension of structural studies of biological components, such as membrane proteins. While X-ray crystallography has been the main method of structure analysis of proteins including membrane proteins, electron crystallography is now an established technique to analyze structures of membrane proteins in the lipid bilayer, which is close to their natural biological environment. By utilizing cryo-electron microscopes with helium-cooled specimen stages, structures of membrane proteins were analyzed at a resolution better than 3 Å. Such high-resolution structural analysis of membrane proteins by electron crystallography opens up the new research field of structural physiology. Considering the fact that the structures of integral membrane proteins in their native membrane environment without artifacts from crystal contacts are critical in understanding their physiological functions, electron crystallography will continue to be an important technology for structural analysis. In this chapter, I will present several examples to highlight important advantages and to suggest future directions of this technique.

  11. Laboratory directed research and development

    Energy Technology Data Exchange (ETDEWEB)

    1991-11-15

    The purposes of Argonne's Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel concepts, enhance the Laboratory's R D capabilities, and further the development of its strategic initiatives. Among the aims of the projects supported by the Program are establishment of engineering proof-of-principle''; development of an instrumental prototype, method, or system; or discovery in fundamental science. Several of these project are closely associated with major strategic thrusts of the Laboratory as described in Argonne's Five Year Institutional Plan, although the scientific implications of the achieved results extend well beyond Laboratory plans and objectives. The projects supported by the Program are distributed across the major programmatic areas at Argonne. Areas of emphasis are (1) advanced accelerator and detector technology, (2) x-ray techniques in biological and physical sciences, (3) advanced reactor technology, (4) materials science, computational science, biological sciences and environmental sciences. Individual reports summarizing the purpose, approach, and results of projects are presented.

  12. Cooperation for direct fitness benefits.

    Science.gov (United States)

    Leimar, Olof; Hammerstein, Peter

    2010-09-12

    Studies of the evolution of helping have traditionally used the explanatory frameworks of reciprocity and altruism towards relatives, but recently there has been an increasing interest in other kinds of explanations. We review the success or otherwise of work investigating alternative processes and mechanisms, most of which fall under the heading of cooperation for direct benefits. We evaluate to what extent concepts such as by-product benefits, pseudo-reciprocity, sanctions and partner choice, markets and the build-up of cross-species spatial trait correlations have contributed to the study of the evolution of cooperation. We conclude that these alternative ideas are successful and show potential to further increase our understanding of cooperation. We also bring up the origin and role of common interest in the evolution of cooperation, including the appearance of organisms. We note that there are still unresolved questions about the main processes contributing to the evolution of common interest. Commenting on the broader significance of the recent developments, we argue that they represent a justified balancing of the importance given to different major hypotheses for the evolution of cooperation. This balancing is beneficial because it widens considerably the range of phenomena addressed and, crucially, encourages empirical testing of important theoretical alternatives.

  13. Orthogonal two-direction multiscaling functions

    Institute of Scientific and Technical Information of China (English)

    XIE Changzhen; YANG Shouzhi

    2006-01-01

    The concept of a two-direction multiscaling functions is introduced.We investigate the existence of solutions of the two-direction matrix refinable equationΦ(x)=Σk∈ZP+kΦ(2x-k) +Σk∈ZP-kΦ&(k- 2x),where r×r matrices {P+k} and {P-k} are called the positive-direction and negative-direction masks,respectively.Necessary and sufficient conditions that the above two-direction matrix refinable equation has a compactly supported distributional solution are established.The definition of orthogonal two-direction multiscaling function is presented,and the orthogonality criteria for two-direction multiscaling function is established.An algorithm for constructing a class of two-direction multiscaling functions is obtained.In addition,the relation of both orthogonal two-direction multiscaling function and orthogonal multiscaling function is discussed.Finally,construction examples are given.

  14. Advance directives: role of nurse practitioners.

    Science.gov (United States)

    Schlenk, J S

    1997-07-01

    Advance directives are documents that guide end of life decisions. Although advance directives are a fairly recent phenomenon in health care, they are grounded in both legal and ethical principles. Studies show few people have completed advance directives. Persons do not tend to complete advance directives for various reasons. Lack of knowledge has been identified, as well as belief that physicians should initiate the discussion and that the topic is appropriate only for the elderly or those in poor health. Many nurse practitioners practice in primary care settings, which are ideal for discussions about advance directives. Nurse practitioners possess the opportunities and skills to discuss advance directives with their patients.

  15. New directions in Quantum Chromodynamics

    Energy Technology Data Exchange (ETDEWEB)

    Brodsky, S.J.

    1999-12-13

    The authors review the light-cone Fock state representation and its associated light-cone factorization scheme as a method for encoding the flavor, momentum, and helicity properties of hadrons in the form of universal process-independent and frame-independent amplitudes. Discrete light-cone quantization (DLCQ) provides a matrix representation of the QCD Hamiltonian and a nonperturbative method for computing the quark and gluon bound state wavefunctions. A number of applications of the light-cone formalism are discussed, including an exact light-cone Fock state representation of semi-leptonic B decay amplitudes. Hard exclusive and diffractive reactions are shown to be sensitive to hadron distribution amplitudes, the valence Fock state hadronic wavefuctions at small impact separation. Semi-exclusive reactions are shown to provide new flavor-dependent probes of distribution amplitudes and new types of deep inelastic currents. ``Self-resolving'' diffractive processes and Coulomb dissociation are discussed as a direct measure of the light-cone wavefunctions of hadrons. Alternatively, one can use Coulomb dissociation to resolve nuclei in terms of their nucleonic and mesonic degrees of freedom. They also discuss several theoretical tools which eliminate theoretical ambiguities in perturbative QCD predictions. For example, commensurate scale relations are perturbative QCD predictions based on conformal symmetry which relate observable to observable at fixed relative scale; such relations have no renormalization scale or scheme ambiguity. They also discuss the utility of the {alpha}V coupling, defined from the QCD heavy quark potential, as a useful physical expansion parameter for perturbative QCD and grand unification. New results on the analytic fermion masses dependence of the {alpha}V coupling at two-loop order are presented.

  16. 38 CFR 17.259 - Direct costs.

    Science.gov (United States)

    2010-07-01

    ... personnel or for fringe benefits, rent, publications, educational programs, training, research... Exchange of Information § 17.259 Direct costs. Direct costs to which grant funds may be applied may...

  17. Wave directional spectrum from array measurements

    Digital Repository Service at National Institute of Oceanography (India)

    Fernandes, A.A; Sarma, Y.V.B.; Menon, H.B.

    Using the method of Esteva (1976, 1977), whcih assumes that at the frequency band the waves approach from just a single "mean" wave direction, wave direction has been consistently, accurately and unambiguously evaluated as a function of frequency...

  18. Implementing the European SEA Directive in planning

    DEFF Research Database (Denmark)

    Kørnøv, Lone

    The paper describes how the European SEA Directive can complement the existing planning practice in Denmark.......The paper describes how the European SEA Directive can complement the existing planning practice in Denmark....

  19. Direct Interval Forecasting of Wind Power

    DEFF Research Database (Denmark)

    Wan, Can; Xu, Zhao; Pinson, Pierre

    2013-01-01

    This letter proposes a novel approach to directly formulate the prediction intervals of wind power generation based on extreme learning machine and particle swarm optimization, where prediction intervals are generated through direct optimization of both the coverage probability and sharpness...

  20. Product directivity models for parametric loudspeakers.

    Science.gov (United States)

    Shi, Chuang; Gan, Woon-Seng

    2012-03-01

    In a recent work, the beamsteering characteristics of parametric loudspeakers were validated in an experiment. It was shown that based on the product directivity model, the locations and amplitudes of the mainlobe and grating lobes could be predicted within acceptable errors. However, the measured amplitudes of sidelobes have not been able to match the theoretical results accurately. In this paper, the original theories behind the product directivity model are revisited, and three modified product directivity models are proposed: (i) the advanced product directivity model, (ii) the exponential product directivity model, and (iii) the combined product directivity model. The proposed product directivity models take the radii of equivalent Gaussian sources into account and obtain better predictions of sidelobes for the difference frequency waves. From the comparison between measurement results and numerical solutions, all the proposed models outperform the original product directivity model in terms of selected sidelobe predictions by about 10 dB.

  1. Future directions of ecosystem science

    Science.gov (United States)

    Baron, Jill; Galvin, Kathleen A.

    1990-01-01

    , and global--have not replaced one another (Clark and Holling 1985). Instead, the effects are superimposed, creating what some perceive as impending global environmental crisis (Clark 1989, MacNeill 1989, WCED 1987). Public demands are developing for economic, political, social, and environmental efforts directed toward creating a state of global sustainability.

  2. Direct interpretation of dreams: typology.

    Science.gov (United States)

    van den Daele, L

    1992-12-01

    remarkable stasis in the psychoanalytic theory of the unconscious. The theory of the unconscious that arises from the method of direct interpretation reflects a differentiated inner world with variegated landscapes of images and frameworks. The derivatives of the unconscious are determined by complex decision rules, symbol systems, and syntax. Images and dreams possess a primary autonomy from the conscious mind and arise through the configural mind, which serves the construction and synthesis of experience and knowledge. The derivatives emerge out of common human nature conjoined with concrete human experience. For this reason, dreams and images appear universal.(ABSTRACT TRUNCATED AT 400 WORDS)

  3. MAPPING DIRECTLY IMAGED GIANT EXOPLANETS

    Energy Technology Data Exchange (ETDEWEB)

    Kostov, Veselin [Department of Physics and Astronomy, Johns Hopkins University, 366 Bloomberg Center, 3400 North Charles Street, Baltimore, MD 21218 (United States); Apai, Daniel, E-mail: vkostov@pha.jhu.edu [Department of Astronomy, The University of Arizona, 933 North Cherry Avenue, Tucson, AZ 85718 (United States)

    2013-01-01

    With the increasing number of directly imaged giant exoplanets, the current atmosphere models are often not capable of fully explaining the spectra and luminosity of the sources. A particularly challenging component of the atmosphere models is the formation and properties of condensate cloud layers, which fundamentally impact the energetics, opacity, and evolution of the planets. Here we present a suite of techniques that can be used to estimate the level of rotational modulations these planets may show. We propose that the time-resolved observations of such periodic photometric and spectroscopic variations of extrasolar planets due to their rotation can be used as a powerful tool to probe the heterogeneity of their optical surfaces. In this paper, we develop simulations to explore the capabilities of current and next-generation ground- and space-based instruments for this technique. We address and discuss the following questions: (1) what planet properties can be deduced from the light curve and/or spectra, and in particular can we determine rotation periods, spot coverage, spot colors, and spot spectra?; (2) what is the optimal configuration of instrument/wavelength/temporal sampling required for these measurements?; and (3) can principal component analysis be used to invert the light curve and deduce the surface map of the planet? Our simulations describe the expected spectral differences between homogeneous (clear or cloudy) and patchy atmospheres, outline the significance of the dominant absorption features of H{sub 2}O, CH{sub 4}, and CO, and provide a method to distinguish these two types of atmospheres. Assuming surfaces with and without clouds for most currently imaged planets the current models predict the largest variations in the J band. Simulated photometry from current and future instruments is used to estimate the level of detectable photometric variations. We conclude that future instruments will be able to recover not only the rotation periods

  4. Directional detection of galactic dark matter

    CERN Document Server

    Mayet, F; Santos, D

    2012-01-01

    Directional detection is a promising Dark Matter search strategy. Taking advantage on the rotation of the Solar system around the galactic center through the Dark Matter halo, it allows to show a direction dependence of WIMP events that may be a powerful tool to identify genuine WIMP events as such. Directional detection strategy requires the simultaneous measurement of the energy and the 3D track of low energy recoils, which is a common challenge for all current projects of directional detectors.

  5. Theoretical prospects for directional WIMP detection

    CERN Document Server

    O'Hare, Ciaran A J

    2015-01-01

    Direct detection of dark matter with directional sensitivity is a promising concept for improving the search for weakly interacting massive particles. With information on the direction of WIMP induced nuclear recoils one has access to the full 3-dimensional velocity distribution of the local dark matter halo and thus a potential avenue for studying WIMP astrophysics. Furthermore the unique angular signature of the WIMP recoil distribution provides a crucial discriminant from neutrinos which currently represent the ultimate background to direct detection experiments.

  6. Hydrothermal industrialization: direct heat development. Final report

    Energy Technology Data Exchange (ETDEWEB)

    1982-05-01

    A description of hydrothermal resources suitable for direct applications, their associated temperatures, geographic distribution and developable capacity are given. An overview of the hydrothermal direct-heat development infrastructure is presented. Development activity is highlighted by examining known and planned geothermal direct-use applications. Underlying assumptions and results for three studies conducted to determine direct-use market penetration of geothermal energy are discussed.

  7. AIRTV: Broadband Direct to Aircraft

    Science.gov (United States)

    Sorbello, R.; Stone, R.; Bennett, S. B.; Bertenyi, E.

    2002-01-01

    Airlines have been continuously upgrading their wide-body, long-haul aircraft with IFE (in-flight entertainment) systems that can support from 12 to 24 channels of video entertainment as well as provide the infrastructure to enable in-seat delivery of email and internet services. This is a direct consequence of increased passenger demands for improved in-flight services along with the expectations that broadband delivery systems capable of providing live entertainment (news, sports, financial information, etc.) and high speed data delivery will soon be available. The recent events of Sept. 11 have slowed the airline's upgrade of their IFE systems, but have also highlighted the compelling need for broadband aeronautical delivery systems to include operational and safety information. Despite the impact of these events, it is estimated that by 2005 more than 3000 long haul aircraft (servicing approximately 1 billion passengers annually) will be fully equipped with modern IFE systems. Current aircraft data delivery systems, which use either Inmarsat or NATS, are lacking in bandwidth and consequently are unsuitable to satisfy passenger demands for broadband email/internet services or the airlines' burgeoning data requirements. Present live video delivery services are limited to regional coverage and are not readily expandable to global or multiregional service. Faced with a compelling market demand for high data transport to aircraft, AirTV has been developing a broadband delivery system that will meet both passengers' and airlines' needs. AirTV is a global content delivery system designed to provide a range of video programming and data services to commercial airlines. When AirTV is operational in 2004, it will provide a broadband connection directly to the aircraft, delivering live video entertainment, internet/email service and essential operational and safety data. The system has been designed to provide seamless global service to all airline routes except for those

  8. 16 CFR 1000.13 - Directives System.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Directives System. 1000.13 Section 1000.13 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL COMMISSION ORGANIZATION AND FUNCTIONS § 1000.13 Directives System. The Commission maintains a Directives System which contains delegations...

  9. 12 CFR 619.9135 - Direct lender.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Direct lender. 619.9135 Section 619.9135 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM DEFINITIONS § 619.9135 Direct lender. The term direct lender refers to Farm Credit banks and associations (production credit...

  10. Empirical Evaluation of Directional-Dependence Tests

    Science.gov (United States)

    Thoemmes, Felix

    2015-01-01

    Testing of directional dependence is a method to infer causal direction that recently has attracted some attention. Previous examples by e.g. von Eye and DeShon (2012a) and extensive simulation studies by Pornprasertmanit and Little (2012) have demonstrated that under specific assumptions, directional-dependence tests can recover the true causal…

  11. Horizontal Directional Drilling (HDD) Technology and Applications

    Institute of Scientific and Technical Information of China (English)

    J. G. Cai; X. N. Wang

    2004-01-01

    @@ 1 What is Horizontal Directional Drilling? Horizontal Directional Drilling, accurately steered drilling, has become state -of- the -art drilling technique in the world. Specially- designed directionsteerable corebarrel and accurate direction measurement tool are available for the use together with wire line core drilling machine. That makes it feasible to extract cores and to measure the drill travel line &length while drilling in a curve.

  12. 47 CFR 101.115 - Directional antennas.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Directional antennas. 101.115 Section 101.115... SERVICES Technical Standards § 101.115 Directional antennas. (a) Unless otherwise authorized upon specific... antenna adjusted with the center of the major lobe of radiation in the horizontal plane directed...

  13. Z-direction fiber orientation in paperboard

    Science.gov (United States)

    John M. Considine; David W. Vahey; Roland Gleisner; Alan Rudie; Sabine Rolland du Roscoat; Jean-Francis Bloch

    2010-01-01

    This work evaluated the use of conventional tests to show beneficial attributes of z-direction fiber orientation (ZDFO) for structural paperboards. A survey of commercial linerboards indicated the presence of ZDFO in one material that had higher Taber stiffness, out-of-plane shear strength, directional dependence of Scott internal bond strength and directional...

  14. The ECJ and the Mutual Assistance Directive

    NARCIS (Netherlands)

    S.J.C. Hemels (Sigrid)

    2010-01-01

    textabstractIntroduction: In 1977 the European Council adopted the ‘Directive Concerning Mutual Assistance by the competent Authorities of the Member States in the Field of Direct Taxation’.3 The implementation deadline of this Directive was 1 January 1979. On 6 December 1979 the Council adopted an

  15. The ECJ and the Mutual Assistance Directive

    NARCIS (Netherlands)

    S.J.C. Hemels (Sigrid)

    2010-01-01

    textabstractIntroduction: In 1977 the European Council adopted the ‘Directive Concerning Mutual Assistance by the competent Authorities of the Member States in the Field of Direct Taxation’.3 The implementation deadline of this Directive was 1 January 1979. On 6 December 1979 the Council adopted an

  16. Direct manipulation of virtual objects

    Science.gov (United States)

    Nguyen, Long K.

    Interacting with a Virtual Environment (VE) generally requires the user to correctly perceive the relative position and orientation of virtual objects. For applications requiring interaction in personal space, the user may also need to accurately judge the position of the virtual object relative to that of a real object, for example, a virtual button and the user's real hand. This is difficult since VEs generally only provide a subset of the cues experienced in the real world. Complicating matters further, VEs presented by currently available visual displays may be inaccurate or distorted due to technological limitations. Fundamental physiological and psychological aspects of vision as they pertain to the task of object manipulation were thoroughly reviewed. Other sensory modalities -- proprioception, haptics, and audition -- and their cross-interactions with each other and with vision are briefly discussed. Visual display technologies, the primary component of any VE, were canvassed and compared. Current applications and research were gathered and categorized by different VE types and object interaction techniques. While object interaction research abounds in the literature, pockets of research gaps remain. Direct, dexterous, manual interaction with virtual objects in Mixed Reality (MR), where the real, seen hand accurately and effectively interacts with virtual objects, has not yet been fully quantified. An experimental test bed was designed to provide the highest accuracy attainable for salient visual cues in personal space. Optical alignment and user calibration were carefully performed. The test bed accommodated the full continuum of VE types and sensory modalities for comprehensive comparison studies. Experimental designs included two sets, each measuring depth perception and object interaction. The first set addressed the extreme end points of the Reality-Virtuality (R-V) continuum -- Immersive Virtual Environment (IVE) and Reality Environment (RE). This

  17. The energy efficiency directive; Die Energieeffizienzrichtlinie

    Energy Technology Data Exchange (ETDEWEB)

    Martin, Benedicte [Greifswald Univ. (Germany). Inst. fuer Klimaschutz, Energie und Mobilitaet - Recht, Oekonomie und Politik e.V. (IKEM)

    2012-12-13

    The present article gives an overview of the recently adopted European Energy Efficiency Directive. The Directive is to take effect in early December 2012 and will supersede the Energy Services Directive and the Cogeneration Directive. The Energy Efficiency Directive is dedicated to current European energy saving goals. To this end it contains regulations that are to lead to savings in primary energy as well as final energy use. One that deserves particular mention is Art. 7, which provides a framework for the introduction of energy saving engagement systems, on the strength of which transmission system operators and/or energy suppliers can be obligated to encourage final customers to implement energy saving measures.

  18. Multipolar interference for directed light emission.

    Science.gov (United States)

    Hancu, Ion M; Curto, Alberto G; Castro-López, Marta; Kuttge, Martin; van Hulst, Niek F

    2014-01-08

    By directing light, optical antennas can enhance light-matter interaction and improve the efficiency of nanophotonic devices. Here we exploit the interference among the electric dipole, quadrupole, and magnetic dipole moments of a split-ring resonator to experimentally realize a compact directional optical antenna. This single-element antenna design robustly directs emission even when covered with nanometric emitters at random positions, outperforming previously demonstrated nanoantennas with a bandwidth of 200 nm and a directivity of 10.1 dB from a subwavelength structure. The advantages of this approach bring directional optical antennas closer to practical applications.

  19. [Direct access to physical therapy services].

    Science.gov (United States)

    Parag, Ayala; Jacobson, Eyal; Afek, Arnon

    2014-07-01

    This article presents findings from professional and scientific articles written on the subject of direct access to physical therapy services. Direct access is sometimes referred to as "self-referral"--the patient does not require a physician's referral prior to receiving physiotherapy treatment. The article provides insight from the experience of countries where direct access is accepted practice, which will serve as a theoretical and scientific basis for the use of direct access in Israel. Findings include the influence of direct access on the health care system: cost-benefit analysis, advantages and challenges, as well as the perspective of main stakeholders: physicians, physical therapists and patient-clients. .

  20. Graphlet-based Characterization of Directed Networks

    Science.gov (United States)

    Sarajlić, Anida; Malod-Dognin, Noël; Yaveroğlu, Ömer Nebil; Pržulj, Nataša

    2016-10-01

    We are flooded with large-scale, dynamic, directed, networked data. Analyses requiring exact comparisons between networks are computationally intractable, so new methodologies are sought. To analyse directed networks, we extend graphlets (small induced sub-graphs) and their degrees to directed data. Using these directed graphlets, we generalise state-of-the-art network distance measures (RGF, GDDA and GCD) to directed networks and show their superiority for comparing directed networks. Also, we extend the canonical correlation analysis framework that enables uncovering the relationships between the wiring patterns around nodes in a directed network and their expert annotations. On directed World Trade Networks (WTNs), our methodology allows uncovering the core-broker-periphery structure of the WTN, predicting the economic attributes of a country, such as its gross domestic product, from its wiring patterns in the WTN for up-to ten years in the future. It does so by enabling us to track the dynamics of a country’s positioning in the WTN over years. On directed metabolic networks, our framework yields insights into preservation of enzyme function from the network wiring patterns rather than from sequence data. Overall, our methodology enables advanced analyses of directed networked data from any area of science, allowing domain-specific interpretation of a directed network’s topology.

  1. Non-Perturbative Flat Direction Decay

    CERN Document Server

    Basboll, A; Riva, F; West, S M; Basboll, Anders; Maybury, David; Riva, Francesco; West, Stephen M.

    2007-01-01

    We argue that supersymmetric flat direction vevs can decay non-perturbatively via preheating. Considering the case of a single flat direction, we explicitly calculate the scalar potential in the unitary gauge for a U(1) theory and show that the mass matrix for excitations around the flat direction has non-diagonal entries which vary with the phase of the flat direction vev. Furthermore, this mass matrix has 2 zero eigenvalues (associated with the excitations along the flat direction) whose eigenstates change with time. We show that these 2 light degrees of freedom are produced copiously in the non-perturbative decay of the flat direction vev. We also comment on the application of these results to the MSSM flat direction H_uL.

  2. A care pathway analysis of tuberculosis patients in benin: Highlights on direct costs and critical stages for an evidence-based decision-making.

    Directory of Open Access Journals (Sweden)

    Samia Laokri

    Full Text Available BACKGROUND: Free tuberculosis control fail to protect patients from substantial medical and non-medical expenditure, thus a greater degree of disaggregation of patient cost is needed to fully capture their context and inform policymaking. METHODS: A retrospective cross-sectional study was conducted on a convenience sample of six health districts of Southern Benin. From August 2008 to February 2009, we recruited all smear-positive pulmonary tuberculosis patients treated under the national strategy in the selected districts. Direct out-of-pocket costs associated with tuberculosis, time delays, and care-seeking pattern were collected from symptom onset to end of treatment. RESULTS: Population description and outcome data were reported for 245 patients of whom 153 completed their care pathway. For them, the median overall direct cost was USD 183 per patient. Payments to traditional healers, self-medication drugs, travel, and food expenditures contributed largely to this cost burden. Patient, provider, and treatment delays were also reported. Pre-diagnosis and intensive treatment stages were the most critical stages, with median expenditure of USD 43 per patient and accounting for 38% and 29% of the overall direct cost, respectively. However, financial barriers differed depending on whether the patient lived in urban or rural areas. CONCLUSIONS: This study delivers new evidence about bottlenecks encountered during the TB care pathway. Financial barriers to accessing the free-of-charge tuberculosis control strategy in Benin remain substantial for low-income households. Irregular time delays and hidden costs, often generated by multiple visits to various care providers, impair appropriate patient pathways. Particular attention should be paid to pre-diagnosis and intensive treatment. Cost assessment and combined targeted interventions embodied by a patient-centered approach on the specific critical stages would likely deliver better program outcomes.

  3. A care pathway analysis of tuberculosis patients in benin: Highlights on direct costs and critical stages for an evidence-based decision-making.

    Science.gov (United States)

    Laokri, Samia; Amoussouhui, Arnaud; Ouendo, Edgard M; Hounnankan, Athanase Cossi; Anagonou, Séverin; Gninafon, Martin; Kassa, Ferdinand; Tawo, Léon; Dujardin, Bruno

    2014-01-01

    Free tuberculosis control fail to protect patients from substantial medical and non-medical expenditure, thus a greater degree of disaggregation of patient cost is needed to fully capture their context and inform policymaking. A retrospective cross-sectional study was conducted on a convenience sample of six health districts of Southern Benin. From August 2008 to February 2009, we recruited all smear-positive pulmonary tuberculosis patients treated under the national strategy in the selected districts. Direct out-of-pocket costs associated with tuberculosis, time delays, and care-seeking pattern were collected from symptom onset to end of treatment. Population description and outcome data were reported for 245 patients of whom 153 completed their care pathway. For them, the median overall direct cost was USD 183 per patient. Payments to traditional healers, self-medication drugs, travel, and food expenditures contributed largely to this cost burden. Patient, provider, and treatment delays were also reported. Pre-diagnosis and intensive treatment stages were the most critical stages, with median expenditure of USD 43 per patient and accounting for 38% and 29% of the overall direct cost, respectively. However, financial barriers differed depending on whether the patient lived in urban or rural areas. This study delivers new evidence about bottlenecks encountered during the TB care pathway. Financial barriers to accessing the free-of-charge tuberculosis control strategy in Benin remain substantial for low-income households. Irregular time delays and hidden costs, often generated by multiple visits to various care providers, impair appropriate patient pathways. Particular attention should be paid to pre-diagnosis and intensive treatment. Cost assessment and combined targeted interventions embodied by a patient-centered approach on the specific critical stages would likely deliver better program outcomes.

  4. A wide-range direction neutron spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Luszik-Bhadra, M. E-mail: marlies.luszik-bhadra@ptb.de; D' Errico, F.; Hecker, O.; Matzke, M

    2002-01-01

    A new device is presented which has been developed for measuring the energy and direction of distribution of neutron fluence in fields of broad energy spectra (thermal to 100 MeV) and with a high background of photon, electron and muon radiation. The device was tested in reference fields with different energy and direction distributions of neutron fluence. The direction-integrated fluence spectra agree fairly well with reference spectra. In all cases, the ambient and personal dose equivalent values calculated from measured direction-differential spectra are within 35% of the reference values. Independent measurements of the directional dose equivalent were performed with a directional dose equivalent monitor based on superheated drop detectors.

  5. Evidence of High Out of Pocket Spending for HIV Care Leading to Catastrophic Expenditure for Affected Patients in Lao People's Democratic Republic.

    Directory of Open Access Journals (Sweden)

    Hubert Barennes

    Full Text Available The scaling up of antiviral treatment (ART coverage in the past decade has increased access to care for numerous people living with HIV/AIDS (PLWHA in low-resource settings. Out-of-pocket payments (OOPs represent a barrier for healthcare access, adherence and ART effectiveness, and can be economically catastrophic for PLWHA and their family. We evaluated OOPs of PLWHA attending outpatient and inpatient care units and estimated the financial burden for their households in the Lao People's Democratic Republic. We assumed that such OOPs may result in catastrophic health expenses in this context with fragile economical balance and low health insurance coverage.We conducted a cross-sectional survey of a randomized sample of routine outpatients and a prospective survey of consecutive new inpatients at two referral hospitals (Setthathirat in the capital city, Savannaket in the province. After obtaining informed consent, PLWHA were interviewed using a standardized 82-item questionnaire including information on socio-economic characteristics, disease history and coping strategies. All OOPs occurring during a routine visit or a hospital stay were recorded. Household capacity-to-pay (overall income minus essential expenses, direct and indirect OOPs, OOPs per outpatient visit and per inpatient stay as well as catastrophic spending (greater than or equal to 40% of the capacity-to-pay were calculated. A multivariate analysis of factors associated with catastrophic spending was conducted.A total of 320 PLWHA [280 inpatients and 40 outpatients; 132 (41.2% defined as poor, and 269 (84.1% on ART] were enrolled. Monthly median household income, essential expenses and capacity-to-pay were US$147.0 (IQR: 86-242, $126 (IQR: 82-192 and $14 (IQR: 19-80, respectively. At the provincial hospital OOPs were higher during routine visits, but three fold lower during hospitalization than in the central hospital ($21.0 versus $18.5 and $110.8 versus $329.8 respectively (p<0

  6. Foreign Direct Investment in Indian Economy.

    OpenAIRE

    Kapoor, Vikas

    2007-01-01

    Over the past few years, India's inward Foreign Direct investment (FDI) has attracted many scholars interest. The objective of this study is to focus on the impact that Foreign Direct investment has for Indian economic growth and development. It seeks to briefly reveal why there has been a recent surge in FDI and also the factors that prevent India from attracting foreign direct investments. Main determinants of FDI will also be revealed in this paper. In addition, this paper also compar...

  7. Evaluation and directions of the photovoltaic technologies

    Energy Technology Data Exchange (ETDEWEB)

    Kazmerski, L.L.; Emery, K.A.; DeBlasio, R. (National Renewable Energy Lab., Golden, CO (United States))

    1994-08-01

    The status of, directions and expectations for photovoltaic technologies are discussed and updated, with emphasis on the performances of cells and modules used in various research and commercial solar cell approaches. Current and projected research and development directions are indicated. Special aspects of the current evolution of photovoltaics from the research laboratory to the commercial arena are discussed, including new programs directed to make this energy resource a viable electricity choice for users worldwide. (Author)

  8. Directional and Attitude Stability Control Kit

    Science.gov (United States)

    2014-07-01

    and Attitude Stability Control Kit Final Progress Report This report outlines progress on the DARPA M3 Program, project “Directional and Attitude ...2 ABSTRACT Number of Papers published in peer-reviewed journals: Number of Papers published in non peer-reviewed journals: Directional and Attitude ...Stability Control Kit Final Progress Report Report Title This report outlines progress on the DARPA M3 Program, project “Directional and Attitude

  9. Direct conversion of algal biomass to biofuel

    Science.gov (United States)

    Deng, Shuguang; Patil, Prafulla D; Gude, Veera Gnaneswar

    2014-10-14

    A method and system for providing direct conversion of algal biomass. Optionally, the method and system can be used to directly convert dry algal biomass to biodiesels under microwave irradiation by combining the reaction and combining steps. Alternatively, wet algae can be directly processed and converted to fatty acid methyl esters, which have the major components of biodiesels, by reacting with methanol at predetermined pressure and temperature ranges.

  10. Spatial roles and verbal directionality in Dinka

    DEFF Research Database (Denmark)

    Andersen, Torben

    2012-01-01

    This article deals with the interaction between two subsystems of the grammar of Dinka, a Western Nilotic language: (i) the semantic role of a place adverbial as location, source or goal, and (ii) deictic directionality expressed in the verb. Some place adverbials do not encode the distinction be...... verb. In clauses with a single place adverbial, moreover, a source adverbial requires either a non-directional verb or a centripetal verb, and a location adverbial requires a non-directional verb....

  11. The far future of exoplanet direct characterization

    CERN Document Server

    Schneider, Jean; Fridlund, Malcolm; White, Glenn; Eiroa, Carlos; Henning, Thomas; Herbst, Tom; Lammer, Helmut; Liseau, Rene; Paresce, Francesco; Penny, Alan; Quirrenbach, Andreas; Roettgering, Huub; Selsis, Franck; Beichman, Charles; Danchi, William; Kaltenegger, Lisa; Lunine, Jonathan; Stam, Daphne; Tinetti, Giovanna

    2009-01-01

    In this outlook we describe what could be the next steps of the direct characterization of habitable exoplanets after first the medium and large mission projects and investigate the benefits of the spectroscopic and direct imaging approaches. We show that after third and fourth generation missions foreseeable for the next 100 years, we will face a very long era before being able to see directly the morphology of extrasolar organisms.

  12. The far future of exoplanet direct characterization.

    Science.gov (United States)

    Schneider, Jean; Léger, Alain; Fridlund, Malcolm; White, Glenn J; Eiroa, Carlos; Henning, Thomas; Herbst, Tom; Lammer, Helmut; Liseau, René; Paresce, Francesco; Penny, Alan; Quirrenbach, Andreas; Röttgering, Huub; Selsis, Franck; Beichman, Charles; Danchi, William; Kaltenegger, Lisa; Lunine, Jonathan; Stam, Daphne; Tinetti, Giovanna

    2010-01-01

    We describe future steps in the direct characterization of habitable exoplanets subsequent to medium and large mission projects currently underway and investigate the benefits of spectroscopic and direct imaging approaches. We show that, after third- and fourth-generation missions have been conducted over the course of the next 100 years, a significant amount of time will lapse before we will have the capability to observe directly the morphology of extrasolar organisms.

  13. China's Outward Direct and Portfolio Investments

    Institute of Scientific and Technical Information of China (English)

    Hung-Gay Fung; Qingfeng Wilson Liu; Erin H. C. Kao

    2007-01-01

    This paper analyzes developments and trends related to China's outward direct and financial investments by examining Chinese firms' overseas acquisitions, China's holdings of US Treasury securities, and the recently formally launched Qualified Domestic Institutional Investor programs. Strategies should be developed to reach optimal decisions for both direct and portfolio investments. We argue that China should have a longer-term view for both direct and portfolio investments, enabling China to become the leader in Asia while maintaining its sustainable growth objective. China should invest heavily in the development of the Asian bond market and the Asian Currency Fund when making both portfolio and direct investment decisions.

  14. Ionization based multi-directional flow sensor

    Science.gov (United States)

    Chorpening, Benjamin T.; Casleton, Kent H.

    2009-04-28

    A method, system, and apparatus for conducting real-time monitoring of flow (airflow for example) in a system (a hybrid power generation system for example) is disclosed. The method, system and apparatus measure at least flow direction and velocity with minimal pressure drop and fast response. The apparatus comprises an ion source and a multi-directional collection device proximate the ion source. The ion source is configured to generate charged species (electrons and ions for example). The multi-directional collection source is configured to determine the direction and velocity of the flow in real-time.

  15. Adaptation to direction statistics modulates perceptual discrimination.

    Science.gov (United States)

    Price, Nicholas S C; Prescott, Danielle L

    2012-06-22

    Perception depends on the relative activity of populations of sensory neurons with a range of tunings and response gains. Each neuron's tuning and gain are malleable and can be modified by sustained exposure to an adapting stimulus. Here, we used a combination of human psychophysical testing and models of neuronal population decoding to assess how rapid adaptation to moving stimuli might change neuronal tuning and thereby modulate direction perception. Using a novel motion stimulus in which the direction changed every 10 ms, we demonstrated that 1,500 ms of adaptation to a distribution of directions was capable of modifying human psychophysical direction discrimination performance. Consistent with previous reports, we found perceptual repulsion following adaptation to a single direction. Notably, compared with a uniform adaptation condition in which all motion directions were equiprobable, discrimination was impaired after adaptation to a stimulus comprising only directions ± 30-60° from the discrimination boundary and enhanced after adaptation to the complementary range of directions. Thus, stimulus distributions can be selectively chosen to either impair or improve discrimination performance through adaptation. A neuronal population decoding model incorporating adaptation-induced repulsive shifts in direction tuning curves can account for most aspects of our psychophysical data; however, changes in neuronal gain are sufficient to account for all aspects of our psychophysical data.

  16. SPECTRUM OF DIRECTED KIRKMAN PACKING DESIGNS

    Institute of Scientific and Technical Information of China (English)

    ZhangYan; DuBeiliang

    2003-01-01

    The problem studied in this article is the directed Kirkman packing, the resolvable directed packing which requires all blocks to be of size three except that ,each resolution class should contain either one block of size two(when v=2(mod 3)) or one block of size four (when v=l (mod 3)). A directed Kirkman packing design DKPD(v) is a resolvable directed packing of a v-set by the maximum possible number of resolution classes of this type. This article investigates the spectrum of DKPD(v) and it is found that it contains all positive integers v≥3 and v≠5,6.

  17. Edge detection based on directional space

    Institute of Scientific and Technical Information of China (English)

    YUAN Wei-qi; LI De-sheng

    2006-01-01

    A new method for edge detection based on directional space is proposed.The principle is that:firstly,the directional differential space is set up in which the ridge edge pixels and valley edge pixels are abstracted with the help of the method of logical judgments along the direction of differential function,forming a directional roof edge map;secondly,step edge pixels are abstracted between the neighboring directional ridge edge and directional valley edge along the direction of differential function;finally,the ridge edge map,valley edge map and step edge map gained along different directions are combined into corresponding ridge edge map,valley edge map and step edge map.This method is different from classical algorithms in which the gray differential values of the mutual vertical direction are combined into one gradient value.The experiment of edge detection is made for the images of nature scenery,human body and accumulative raw material,whose result is compared with the one of classical algorithms and showing the robustness of the proposed method.

  18. 77 FR 24344 - Airworthiness Directives; Learjet Inc.

    Science.gov (United States)

    2012-04-24

    ... airworthiness directive system would not be needed. This commenter justified its request by providing Webster's.... John Piccola, Acting Manager, Transport Airplane Directorate, Aircraft Certification Service....

  19. Gaze Direction Detection in Autism Spectrum Disorder

    Science.gov (United States)

    Forgeot d'Arc, Baudouin; Delorme, Richard; Zalla, Tiziana; Lefebvre, Aline; Amsellem, Frédérique; Moukawane, Sanaa; Letellier, Laurence; Leboyer, Marion; Mouren, Marie-Christine; Ramus, Franck

    2017-01-01

    Detecting where our partners direct their gaze is an important aspect of social interaction. An atypical gaze processing has been reported in autism. However, it remains controversial whether children and adults with autism spectrum disorder interpret indirect gaze direction with typical accuracy. This study investigated whether the detection of…

  20. 5 CFR 330.402 - Direct recruitment.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Direct recruitment. 330.402 Section 330.402 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS RECRUITMENT, SELECTION, AND PLACEMENT (GENERAL) Positions Restricted to Preference Eligibles § 330.402 Direct recruitment...

  1. On the directionality of halogen bonding.

    Science.gov (United States)

    Huber, Stefan M; Scanlon, Joseph D; Jimenez-Izal, Elisa; Ugalde, Jesus M; Infante, Ivan

    2013-07-07

    The origin of the high directionality of halogen bonding was investigated quantum chemically by a detailed comparison of typical adducts in two different orientations: linear (most stable) and perpendicular. Energy decomposition analyses revealed that the synergy between charge-transfer interactions and Pauli repulsion are the driving forces for the directionality, while electrostatic contributions are more favourable in the less-stable, perpendicular orientation.

  2. 75 FR 15387 - Veterinary Feed Directive

    Science.gov (United States)

    2010-03-29

    ... HUMAN SERVICES Food and Drug Administration 21 CFR Parts 510, 514, and 558 Veterinary Feed Directive... relating to veterinary feed directive (VFD) drugs. FDA's VFD regulation, which became effective on January... CONTACT: Neal Bataller, Center for Veterinary Medicine (HFV-230), Food and Drug Administration,...

  3. Presenting directions with a vibrotactile torso display

    NARCIS (Netherlands)

    Erp, J.B.F. van

    2005-01-01

    Vibrotactile displays covering the torso present spatial information in an intuitive way since the stimuli are directly mapped to the body coordinates; left is left, front is front, etc. The present study investigated the direction in the horizontal plane to which a specific torso location is mapped

  4. Approximation Algorithms for Directed Width Parameters

    CERN Document Server

    Kintali, Shiva; Kumar, Akash

    2011-01-01

    Treewidth of an undirected graph measures how close the graph is to being a tree. Several problems that are NP-hard on general graphs are solvable in polynomial time on graphs with bounded treewidth. Motivated by the success of treewidth, several directed analogues of treewidth have been introduced to measure the similarity of a directed graph to a directed acyclic graph (DAG). Directed treewidth, D-width, DAG-width, Kelly-width and directed pathwidth are some such parameters. In this paper, we present the first approximation algorithms for all these five directed width parameters. For directed treewidth and D-width we achieve an approximation factor of O(sqrt{logn}). For DAG-width, Kelly-width and directed pathwidth we achieve an O({\\log}^{3/2}{n}) approximation factor. Our algorithms are constructive, i.e., they construct the decompositions associated with these parameters. The width of these decompositions are within the above mentioned factor of the corresponding optimal width.

  5. Direct Reading Instruction and the NYS ELA

    Science.gov (United States)

    Jones-Carey, Margaret H.

    2013-01-01

    This study analyzed the impact of classroom based reading instruction ("direct instruction") on the standardized test scores of 6th grade students as measured by the New York State English Language Arts assessment (NYS ELA). It was hypothesized that the implementation of direct instruction in reading in grade 6 would improve NYS ELA…

  6. 30 CFR 256.71 - Directional drilling.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Directional drilling. 256.71 Section 256.71... drilling. In accordance with an approved exploration plan or development and production plan, a lease may be maintained in force by directional wells drilled under the leased area from surface locations...

  7. Directed Evolution of Enzymes : Library Screening Strategies

    NARCIS (Netherlands)

    Leemhuis, Hans; Kelly, Ronan M.; Dijkhuizen, Lubbert

    2009-01-01

    Directed evolution has become the preferred engineering approach to generate tailor-made enzymes. The method follows the design guidelines of nature: Darwinian selection of genetic variants. This review discusses the different stages of directed evolution experiments with the focus on developments i

  8. SDR (Systems Directed Reading): An Overview.

    Science.gov (United States)

    Baugo Community Schools, Elkhart, IN.

    The objective of this project for kindergarten through fifth grade is to interest public and private educational institutions in the systematization of elementary school reading programs. Facets of Systems Directed Reading (SDR) include the use of a differentiated staffing pattern; experienced language arts unit leaders guiding and directing all…

  9. Planar antenna system for direction finding

    Science.gov (United States)

    Mardale, Iulia-Cezara; Cocias, Gabriela; Dumitrascu, Ana; Tamas, Razvan; Berescu, Serban

    2015-02-01

    Applications of direction finding techniques include detection and localization of pulsed electromagnetic sources. This paper presents the design and analysis of a planar antenna system for direction finding. Our proposed system includes 4 hybrid couplers that generate 900 shifted signals, 2 crossover couplers also known as 0dB couplers, two 450 phase shifters, two 00 phase shifters and 4 patch antennas.

  10. Direct fired absorption machine flue gas recuperator

    Science.gov (United States)

    Reimann, Robert C.; Root, Richard A.

    1985-01-01

    A recuperator which recovers heat from a gas, generally the combustion gas of a direct-fired generator of an absorption machine. The recuperator includes a housing with liquid flowing therethrough, the liquid being in direct contact with the combustion gas for increasing the effectiveness of the heat transfer between the gas and the liquid.

  11. Silicon nanostructures produced by laser direct etching

    DEFF Research Database (Denmark)

    Müllenborn, Matthias; Dirac, Paul Andreas Holger; Petersen, Jon Wulff

    1995-01-01

    A laser direct-write process has been applied to structure silicon on a nanometer scale. In this process, a silicon substrate, placed in a chlorine ambience, is locally heated above its melting point by a continuous-wave laser and translated by high-resolution direct-current motor stages. Only...

  12. Communicating a direction using spin states

    CERN Document Server

    Bagán, E; Muñoz-Tàpia, R

    2001-01-01

    The communication of directions using quantum states is a useful laboratory test for some basic facts of quantum information. For a system of spin-1/2 particles there are different quantum states that can encode directions. This information can later be decoded by means of a generalized measurement. In this talk we present the optimal strategies under different assumptions.

  13. On the Strong Direct Summand Conjecture

    Science.gov (United States)

    McCullough, Jason

    2009-01-01

    In this thesis, our aim is the study the Vanishing of Maps of Tor Conjecture of Hochster and Huneke. We mainly focus on an equivalent characterization called the Strong Direct Summand Conjecture, due to N. Ranganathan. Our results are separated into three chapters. In Chapter 3, we prove special cases of the Strong Direct Summand Conjecture in…

  14. Addressing resource efficiency through the Ecodesign Directive

    DEFF Research Database (Denmark)

    Dalhammar, Carl; Machacek, Erika; Bundgaard, Anja Marie;

    The European Union has initiated a number of initiatives to improve resource efficiency in Europe. The Ecodesign Directive is one of the policy instruments that could aid the transition towards a more resource efficient economy. So far, the Directive has mainly been applied to set requirements...

  15. Efficient Quantum Secure Direct Communication with Authentication

    Institute of Scientific and Technical Information of China (English)

    LIU Wen-Jie; CHEN Han-Wu; LI Zhi-Qiang; LIU Zhi-Hao

    2008-01-01

    Two protocols of quantum direct communication with authentication [Phys. Rev. A 73 (2006) 042305] were recently indicated to be insecure against the authenticator Trent attacks [Phys. Rev. A 75 (2007) 026301]. We present two efficient protocols by using four Pauli operations, which are secure against inner Trent attacks as well as outer Eve attacks. Finally, we generalize them to multiparty quantum direction communication.

  16. Nonlinear approximation with dictionaries I. Direct estimates

    DEFF Research Database (Denmark)

    Gribonval, Rémi; Nielsen, Morten

    2004-01-01

    with algorithmic constraints: thresholding and Chebychev approximation classes are studied, respectively. We consider embeddings of the Jackson type (direct estimates) of sparsity spaces into the mentioned approximation classes. General direct estimates are based on the geometry of the Banach space, and we prove...

  17. Nonlinear approximation with dictionaries, I: Direct estimates

    DEFF Research Database (Denmark)

    Gribonval, Rémi; Nielsen, Morten

    $-term approximation with algorithmic constraints: thresholding and Chebychev approximation classes are studied respectively. We consider embeddings of the Jackson type (direct estimates) of sparsity spaces into the mentioned approximation classes. General direct estimates are based on the geometry of the Banach space...

  18. Polar-direct-drive simulations and experiments

    Energy Technology Data Exchange (ETDEWEB)

    Marozas, J.A.; Marshall, F.J.; Craxton, R.S.; Igumenshchev, I.V.; Skupsky, S.; Bonino, M.J.; Collins, T.J.B.; Epstein, R.; Glebov, V.Yu.; Jacobs-Perkins, D.; Knauer, J.P.; McCrory, R.L.; McKenty, P.W.; Meyerhofer, D.D.; Noyes, S.G.; Radha, P.B.; Sangster, T.C.; Seka, W.; Smalyuk, V.A.

    2006-05-17

    Polar direct drive (PDD) will allow direct-drive ignition experiments on the National Ignition Facility (NIF) as it is configured for x-ray drive. Optimal drive uniformity is obtained via a combination of beam repointing, pulse shapes, spot shapes, and/or target design. This article describes progress in the development of standard and "Saturn" PDD target designs.

  19. 19 CFR 18.42 - Direct exportation.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Direct exportation. 18.42 Section 18.42 Customs... TRANSPORTATION IN BOND AND MERCHANDISE IN TRANSIT Merchandise Not Otherwise Subject to Customs Control Exported Under Cover of A Tir Carnet § 18.42 Direct exportation. At the port of exportation, the container...

  20. Directional coupling for quantum computing and communication.

    Science.gov (United States)

    Nikolopoulos, Georgios M

    2008-11-14

    We introduce the concept of directional coupling, i.e., the selective transfer of a state between adjacent quantum wires, in the context of quantum computing and communication. Our analysis rests upon a mathematical analogy between a dual-channel directional coupler and a composite spin system.

  1. Verbal directionality and argument alternation in Dinka

    DEFF Research Database (Denmark)

    Andersen, Torben

    2012-01-01

    (wards) an explicit or implicit goal. The object of a directional verb may play another role in the event described by the sentence than the object of the corresponding simple (and non-directional) verb. This gives rise to so-called argument alternation, in that, for instance, an object and an instrumental adverbial...

  2. Simulation Modeling of Radio Direction Finding Results

    Directory of Open Access Journals (Sweden)

    K. Pelikan

    1994-12-01

    Full Text Available It is sometimes difficult to determine analytically error probabilities of direction finding results for evaluating algorithms of practical interest. Probalistic simulation models are described in this paper that can be to study error performance of new direction finding systems or to geographical modifications of existing configurations.

  3. Energy and Directional Distribution of Neutrons

    Energy Technology Data Exchange (ETDEWEB)

    Matzke, M.; Hecker, O.; Luszik-Bhadra, M. [Braunschweig (Germany); D' Errico, F. [New Haven (United States)

    1999-07-01

    An unfolding method is described for determining the directional spectral fluence of neutron fields from the readings of detectors mounted on a polyethylene sphere. Two detector systems are considered, both of the directly indicating type: a specially designed superheated drop (bubble) detector and a recently developed electronic dosemeter. The results obtained in two neutron reference fields are discussed. (author)

  4. Hopes and Directions for the Future

    Science.gov (United States)

    Wehlburg, Catherine M.

    2010-01-01

    Many significant changes have taken place in higher education since the first issue of "New Directions for Teaching and Learning" (NDTL) was published in 1980. The purpose of this final chapter in this issue is to consider the directions that higher education may be taking in the future. Although it is difficult to predict accurately what will…

  5. Direction coding using a tactile chair

    NARCIS (Netherlands)

    Vries, S.C. de; Erp, J.B.F. van; Kiefer, R.J.

    2009-01-01

    This laboratory study examined the possibility of using a car seat instrumented with tactile display elements (tactors) to communicate directional information to a driver. A car seat fitted with an 8 by 8 matrix of tactors embedded in the seat pan was used to code eight different directions.Localiza

  6. Direct nanofiltration of wastewater treatment plant effluent

    NARCIS (Netherlands)

    Schrader, Guillo Alexander

    2006-01-01

    Membrane technology, especially nanofiltration, is seen as a suitable technology to polish WWTP effluent to EU WFD standards and consequently produce an effluent quality suitable for agricultural or (in)direct potable usage. The objective of this study was to assess the potential of direct nanofiltr

  7. Deriving directions through procedural task analysis.

    Science.gov (United States)

    Yuen, H K; D'Amico, M

    1998-01-01

    Task analysis is one of the essential components of activity analysis. Procedural task analysis involves breaking down an activity into a sequence of steps. Directions are the sequence of steps resulting from the task analysis (i.e., the product of the task analysis). Directions become a guide for caregivers or trainers use in teaching clients a specific skill. However, occupational therapy students often have difficulty in writing directions that are clear enough for caregivers or trainers to carry out. Books on activity analysis only provide examples of directions without giving guidelines on how to perform the writing process. The purposes of this paper are to describe the process of procedural task analysis and to provide a guideline for writing steps of directions.

  8. Comparison of direct and indirect radionuclide cystography

    Energy Technology Data Exchange (ETDEWEB)

    Bower, G.; Lovegrove, F.T.; Geijsel, H.; Van der Schaff, A.; Guelfi, G.

    1985-05-01

    Thirty children were studied using both direct (catheter) and indirect techniques of radionuclide cystography. Of 54 ureters able to be compared, six showed vesicoureteric reflux (VUR) on the direct study but were read as negative on the indirect cystogram, and five showed no reflux on the direct cystogram but were read as positive for VUR on the indirect study. Regarding ureters read as true positives on indirect study, if that ureter has ever shown reflux at any time, or if it drained a scarred kidney specificity was improved to 97% without changing the sensitivity. Concerns about the validity of indirect cystogram results and the ease of assessment and low radiation dose from the direct cystogram has made direct cystography our preferred technique.

  9. Reasoning about Cardinal Directions between Extended Objects

    CERN Document Server

    Zhang, Xiaotong; Li, Sanjiang; Ying, Mingsheng

    2009-01-01

    Direction relations between extended spatial objects are important commonsense knowledge. Recently, Goyal and Egenhofer proposed a formal model, known as Cardinal Direction Calculus (CDC), for representing direction relations between connected plane regions. CDC is perhaps the most expressive qualitative calculus for directional information, and has attracted increasing interest from areas such as artificial intelligence, geographical information science, and image retrieval. Given a network of CDC constraints, the consistency problem is deciding if the network is realizable by connected regions in the real plane. This paper provides a cubic algorithm for checking consistency of basic CDC constraint networks, and proves that reasoning with CDC is in general an NP-Complete problem. For a consistent network of basic CDC constraints, our algorithm also returns a 'canonical' solution in cubic time. This cubic algorithm is also adapted to cope with cardinal directions between possibly disconnected regions, in whic...

  10. Novel Random Mutagenesis Method for Directed Evolution.

    Science.gov (United States)

    Feng, Hong; Wang, Hai-Yan; Zhao, Hong-Yan

    2017-01-01

    Directed evolution is a powerful strategy for gene mutagenesis, and has been used for protein engineering both in scientific research and in the biotechnology industry. The routine method for directed evolution was developed by Stemmer in 1994 (Stemmer, Proc Natl Acad Sci USA 91, 10747-10751, 1994; Stemmer, Nature 370, 389-391, 1994). Since then, various methods have been introduced, each of which has advantages and limitations depending upon the targeted genes and procedure. In this chapter, a novel alternative directed evolution method which combines mutagenesis PCR with dITP and fragmentation by endonuclease V is described. The kanamycin resistance gene is used as a reporter gene to verify the novel method for directed evolution. This method for directed evolution has been demonstrated to be efficient, reproducible, and easy to manipulate in practice.

  11. Boosters and barriers for direct cardiac reprogramming.

    Science.gov (United States)

    Talkhabi, Mahmood; Zonooz, Elmira Rezaei; Baharvand, Hossein

    2017-06-01

    Heart disease is currently the most significant cause of morbidity and mortality worldwide, which accounts for approximately 33% of all deaths. Recently, a promising and alchemy-like strategy has been developed called direct cardiac reprogramming, which directly converts somatic cells such as fibroblasts to cardiac lineage cells such as cardiomyocytes (CMs), termed induced CMs or iCMs. The first in vitro cardiac reprogramming study, mediated by cardiac transcription factors (TFs)-Gata4, Tbx5 and Mef2C-, was not enough efficient to produce an adequate number of fully reprogrammed, functional iCMs. As a result, numerous combinations of cardiac TFs exist for direct cardiac reprogramming of mouse and human fibroblasts. However, the efficiency of direct cardiac reprogramming remains low. Recently, a number of cellular and molecular mechanisms have been identified to increase the efficiency of direct cardiac reprogramming and the quality of iCMs. For example, microgrooved substrate, cardiogenic growth factors [VEGF, FGF, BMP4 and Activin A], and an appropriate stoichiometry of TFs boost the direct cardiac reprogramming. On the other hand, serum, TGFβ signaling, activators of epithelial to mesenchymal transition, and some epigenetic factors (Bmi1 and Ezh2) are barriers for direct cardiac reprogramming. Manipulating these mechanisms by the application of boosters and removing barriers can increase the efficiency of direct cardiac reprogramming and possibly make iCMs reliable for cell-based therapy or other potential applications. In this review, we summarize the latest trends in cardiac TF- or miRNA-based direct cardiac reprogramming and comprehensively discuses all molecular and cellular boosters and barriers affecting direct cardiac reprogramming. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. Stiff directed lines in random media.

    Science.gov (United States)

    Boltz, Horst-Holger; Kierfeld, Jan

    2013-07-01

    We investigate the localization of stiff directed lines with bending energy by a short-range random potential. We apply perturbative arguments, Flory scaling arguments, a variational replica calculation, and functional renormalization to show that a stiff directed line in 1+d dimensions undergoes a localization transition with increasing disorder for d>2/3. We demonstrate that this transition is accessible by numerical transfer matrix calculations in 1+1 dimensions and analyze the properties of the disorder-dominated phase in detail. On the basis of the two-replica problem, we propose a relation between the localization of stiff directed lines in 1+d dimensions and of directed lines under tension in 1+3d dimensions, which is strongly supported by identical free-energy distributions. This shows that pair interactions in the replicated Hamiltonian determine the nature of directed line localization transitions with consequences for the critical behavior of the Kardar-Parisi-Zhang equation. We support the proposed relation to directed lines via multifractal analysis, revealing an analogous Anderson transition-like scenario and a matching correlation length exponent. Furthermore, we quantify how the persistence length of the stiff directed line is reduced by disorder.

  13. Use of direct marketing in nonprofit organizations

    Directory of Open Access Journals (Sweden)

    Popović Ana

    2010-01-01

    Full Text Available Non profit organizations represent very heterogenus group of organizations which can be determined by the fact that they are being used as forums for creation and distribution of new ideas. Their aim is to raise public awareness on the purpose they promote and get the reply for their initiatives for gaining support in form of monetary sources for charities, vote for political candidate or achieving a communicational goal. Non governmental organizations, as the dominant form of non profit organizations, are being founded with mission to raise public awareness on some issue or provide help to certain marginalized group. The direct marketing instruments and techniques are considered to be very useful for achieving mission formulated that way. They are, by their nature, precisely targeted and objective-oriented and require direct reply. Apart from that, direct marketing activities are cost-efficient, costs that they generate can be shown in financial reports, and results of undertaken initiatives are directly measurable. All the mentioned lead to conclusion that direct marketing is, for additional reasons, even more appropriate for NPOs having in mind that they usually have limited available resources. In the relevant literature two main roles of direct marketing in non profit organizations are mentioned - managing relations with representatives of stakeholder groups and fundraising. In this paper, therefore, after the facts referring functioning of NPOs, direct marketing strategies used for mentioned purposes will be presented consequently.

  14. Personalized direct marketing using digital publishing

    Science.gov (United States)

    Kutty, Cheeniyil L.; Prabhakaran, Jayasree K.

    2006-02-01

    In today's cost-conscious business climate, marketing and customer service decision makers are increasingly concerned with how to increase customer response and retention rates. Companies spend large amounts of money on Customer Relationship Management (CRM) solutions and data acquisition but they don't know how to use the information stored in these systems to improve the effectiveness of their direct marketing campaigns. By leveraging the customer information they already have, companies can create personalized, printed direct mail programs that generate high response rates, greater returns, and stronger customer loyalty, while gaining a significant edge over their competitors. To reach the promised land of one-to-one direct marketing (personalized direct marketing - PDM), companies need an end-to-end solution for creating, managing, printing, and distributing personalized direct mail "on demand." Having access to digital printing is just one piece of the solution. A more complete approach includes leveraging personalization technology into a useful direct marketing tool that provides true one-to-one marketing, allowing variable images and text in a personalized direct mail. This paper discusses integration of CRM with a Print-on-Demand solution so as to create truly personalized printed marketing campaigns for one or many individuals based on the profile information, preferences and purchase history stored in the CRM.

  15. FOREIGN DIRECT INVESTMENTS DURING FINANCIAL CRISES

    Directory of Open Access Journals (Sweden)

    VINTILA DENISIA MARIANA

    2011-12-01

    Full Text Available The fundamental idea of International capital flows is that short-term flows can be easily reversed, while flows on a longer time horizon are more stable. Crises are associated with withdrawals of short-term capital flows and growth of the foreign direct investment flows. The current crisis has meant a major decline of international capital flows, also of the foreign direct investment. The analysis in this article tries to establish if and under which conditions foreign direct investments can bring greater stability during the crisis, comparing the evolution of foreign direct investments in the current crisis with their response in previous crises. We show that during previous crises foreign direct investments were stable, behaving differently from other types of capital. Yet, during the current crisis, foreign direct investments have proven to be not so stable and all the components declined, raising questions about the resumption of the positive trend. The stability of foreign direct investments in the past was given by the increase of mergers and acquisitions during the crisis, reflecting fire-sale FDI. This feature is not found in the current crisis as mergers and acquisitions were severe affected by the crises and recorded a major decline. The current paper is realized in the doctoral program entitled PhD in economics at the standards of European knowledge- DoEsEc, scientific coordinator Prof. PhD Rodica Zaharia, institution The Academy of Economic Studies Bucharest, Faculty of International Business, period of research 2009-2012.

  16. Directed Energy Missions for Planetary Defense

    OpenAIRE

    Lubin, P.; Hughes, GB; Eskenazi, M; Kosmo, K.; Johansson, IE; Griswold, J., Ian,;Zhou, Hongjun,;Matison, Mikenzie,;Swanson, V., Ronald,;McIntosh, P., Lawrence,;Simon, I., Melvin,;Dahlquist, W., Frederick,; Pryor, M; O'Neill, H.; Meinhold, P.; Suen, J; J; Riley; Zhang, Q.; Walsh, K.; Melis, C.; Kangas, M

    2016-01-01

    Directed energy for planetary defense is now a viable option and is superior in many ways to other proposed technologies, being able to defend the Earth against all known threats. This paper presents basic ideas behind a directed energy planetary defense system that utilizes laser ablation of an asteroid to impart a deflecting force on the target. A conceptual philosophy called DE-STAR, which stands for Directed Energy System for Targeting of Asteroids and exploRation, is an orbiting stand-of...

  17. Implementing effective staff education about advance directives.

    Science.gov (United States)

    DesRosiers, M; Navin, P

    1997-01-01

    The Patient Self-Determination Act of 1990 guarantees the right to refuse medical or surgical treatment and the right to draft advance directives. This review of the current literature provides those in nursing staff development and inservice education with an overview of advance directives and their implications for nursing education and practice. Possible core subjects for inclusion in planned, purposeful, advance directive education programs are examined, including cultural sensitivity, facilitator skills, interviewing techniques, legal information, patient autonomy, and reasoning and decision making. This review provides a platform for future research.

  18. A simple model of direct gauge mediation

    Energy Technology Data Exchange (ETDEWEB)

    Zheng Sibo, E-mail: sibozheng.zju@gmail.com [Department of Physics, Chongqing University, Chongqing 401331 (China); Yu Yao [Department of Physics, Chongqing University, Chongqing 401331 (China)

    2012-03-23

    In the context of direct gauge mediation Wess-Zumino models are very attractive in supersymmetry model building. Besides the spontaneous supersymmetry and R-symmetry breaking, the problems of small gaugino mass as well as {mu} and B{mu} terms should be solved so as to achieve a viable model. In this Letter, we propose a simple model as an existence proof, in which all these subjects are realized simultaneously, with no need of fine tuning. This completion also implies that much of parameter space for direct gauge mediation can be directly explored at LHC.

  19. Directional Transverse Oscillation Vector Flow Estimation

    DEFF Research Database (Denmark)

    Jensen, Jørgen Arendt

    2017-01-01

    A method for estimating vector velocities using transverse oscillation (TO) combined with directional beamforming is presented. In Directional Transverse Oscillation (DTO) a normal focused field is emitted and the received signals are beamformed in the lateral direction transverse to the ultrasou...... increase in SD to 15.7%, but a maintained bias of -3.5% from 126 to 156 mm. Data for a pulsating flow has also been acquired for 15 cardiac cycles using a CompuFlow 1000 pump. The relative SD was here 7.4% for a femoral artery waveform....

  20. Directed cell movement in pulsed electric fields.

    Science.gov (United States)

    Franke, K; Gruler, H

    1994-01-01

    Human granulocytes exposed to pulsed electric guiding fields were investigated. The trajectories were determined from digitized pictures (phase contrast). The basic results are: (i) No directed response was induced by pulsed electric guiding fields having a zero averaged field. (ii) A directed response was induced by pulsed electric guiding fields having a non-zero averaged field. (iii) The directed response was enhanced for pulse sequences having a repetition time of 8 s. (iv) The lag-time between signal recognition and cellular response was 8-10 s. The results are discussed in the framework of a self-ignition model.