WorldWideScience

Sample records for nicole passonno stott

  1. La ciencia-filosofía en Eduardo Nicol

    Directory of Open Access Journals (Sweden)

    González Valenzuela, Juliana

    2008-12-01

    Full Text Available In 2007 is commemorated the centenary of Eduardo Nicol, one of the philosophers of Spanish language more outstanding of last decades. With his renoved and reformer vision of the sciencephilosophy, as this one was originally expressed by the Greeks, Nicol confronted the radical crisis that beat to the thought, understood as a free vocation, under the pressure of the modern utilitarism and his current culmination in the imperalism of the technocracy.En 2007 se conmemora el centenario de Eduardo Nicol, uno de los filósofos de lengua española más sobresalientes de las últimas décadas. Con su renovada y reformadora visión de la ciencia-filosofía, tal y como ésta fue originariamente expresada por los griegos, Nicol afrontó la crisis radical por la que atraviesa el pensar, entendido como una vocación libre, bajo la presión del utilitarismo moderno y su culminación actual en el imperalismo de la tecnocracia.

  2. Le « commerce d’amour-propre » selon Pierre Nicole

    Directory of Open Access Journals (Sweden)

    Dominique Weber

    2007-04-01

    Full Text Available La notion de « commerce d’amour-propre » telle qu’elle a été élaborée par Pierre Nicole constitue-t-elle une sorte de préfiguration de l’utilitarisme moderne ? Il est commun de le penser. Mais c’est peut-être là faire trop peu de cas du soubassement théologique augustinien de la doctrine de Nicole. Pour analyser le problème, il convient de confronter la pensée de Nicole à celles de Pascal, de Hobbes et de saint Augustin lui-même.

  3. Hopf solitons in the Nicole model

    International Nuclear Information System (INIS)

    Gillard, Mike; Sutcliffe, Paul

    2010-01-01

    The Nicole model is a conformal field theory in a three-dimensional space. It has topological soliton solutions classified by the integer-valued Hopf charge, and all currently known solitons are axially symmetric. A volume-preserving flow is used to construct soliton solutions numerically for all Hopf charges from 1 to 8. It is found that the known axially symmetric solutions are unstable for Hopf charges greater than 2 and new lower energy solutions are obtained that include knots and links. A comparison with the Skyrme-Faddeev model suggests many universal features, though there are some differences in the link types obtained in the two theories.

  4. Influencia del Pseudo Dionisio en Nicolás de Cusa

    Directory of Open Access Journals (Sweden)

    Andrés Hubert R

    2007-01-01

    Full Text Available Nicolás de Cusa (1401-1464 reconoce la influencia del Pseudo Dionisio en su propio pensamiento, especialmente en su teología negativa. Este trabajo busca mostrar esta influencia en el libro referencia del Cusano: el De Docta Ignorantia (la Docta Ignorancia. Esta obra consta de 3 partes. Solo en la primera parte, Nicolás sigue de cerca las ideas del Pseudo Dionisio y solo en ella lo cita. En las demás, aunque se nota la influencia, nuestro autor se siente más libre: las fundaciones están firmes, el constructor puede construir libremente. Para probar esta tesis, se toman dos ejemplos: el tema de las tinieblas y la coincidencia de los opuestos. Este ejercicio permite conocer cómo y por qué se recibió al Pseudo Dionisio en la historia de la teología. Permite también profundizar el sentido de la teología de Nicolás de CusaThe reflections of Nicolas of Cusa (1401-1464 recognise the influence of Pseudo Dyonisius, particularly in his negative theology. The present study shows this influence on Nicolas' most important book: the De Docta Ignorantia (the Learned Ignorance. The book is divided into three parts and it is in the first part that Nicolas directly pursues the ideas of Pseudo Dyonisius and it is only here that he quotes them. In the other parts of the book although the influence is noted, the foundations have been set and are solid and the author or builder can construct with freedom. To prove this thesis, 2 examples are presented: the theme of darkness and the coincidence of opposites. This exercise shows how and why Pseudo Dyonisius has been accepted into the history of the theology. It also deepens the meaning of the Nicolas of Cusa's theology

  5. ESA Press Event: See Mars Express before its departure to the Red Planet

    Science.gov (United States)

    2002-08-01

    There will be ten participants: four ESA astronauts (Pedro Duque, Leopold Eyharts, Paolo Nespoli and Thomas Reiter), four Japanese astronauts from NASDA (Takao Doi, Koichi Wakata, Satoshi Furukawa and Aikihido Hoshide) and two NASA astronauts (Nicole Passonno Stott and Stephanie D. Wilson). The main objective of this training session is to prepare the astronauts for the tasks they will have to perform when the Japanese experiment module (JEM) and ESA's Columbus laboratory are docked with the core of the International Space Station over the years ahead. After completing their training and certification, the astronauts will be assigned to long-duration missions to the ISS. The advanced training at the EAC will focus on the Columbus systems and the Automated Transfer Vehicle (ATV). It will consist of 24 classroom lectures on the Columbus and ATV systems and 4 on payloads, and 2 sessions in the Columbus Trainer. Instructors are being provided by Astrium for the Columbus systems and Alenia Spazio for the ATV, with ESA/EAC staff as mentors for the Columbus payloads. The astronauts are scheduled to visit Astrium in Bremen on 30 August to get acquainted with the flight unit of the Columbus laboratory module currently undergoing integration. This group of astronauts started their advanced training in April 2001 at NASA's Johnson Space Center (JSC), Houston, where they attended a first course on the US segment of the International Space Station. This was followed by training on the JEM system at NASDA's Tsukuba Space Center, Japan, in December 2001 - January 2002 and additional training at the JSC in May 2002. At the beginning of next year the group will be returning to Tsukuba for training on Japanese payloads. Hands-on sessions on Columbus Payload Training Models are scheduled for the second half of 2003, again at ESA's European Astronaut Centre. On Thursday 5 September, between 16:30 and 18:30 hrs, the astronauts and other ESA specialists will be available for interviews

  6. José Nicolás de Azara : un icono del Grand Tour

    Directory of Open Access Journals (Sweden)

    Jorge García Sánchez

    2008-01-01

    Full Text Available José Nicolás de Azara, bien conocido como Agente de Preces y ministro plenipotenciario ante la Santa Sede, fue tal vez la personalidad española de mayor influencia en los círculos intelectuales y artísticos de la Roma del siglo XVIII. Su asumida función de guía ilustrado y su vocación pedagógica para con los jóvenes viajeros lo convirtieron en un auténtico icono del Grand Tour.José Nicolás de Azara, well known as Agente de Preces (Agent of Supplications and ministro plenipotenciario (Plenipotentiary Minister in the Holy See, was perhaps the most influential Spanish personality in the intellectual and artistic circles of Eighteenth-Century Rome. His wilful function of enlightened guide and his pedagogic attitude towards the young travellers made of him an authentic icon of the Grand Tour.

  7. Siim Nestor soovitab : Goldie. Kevin Saunderson. Nicole Willis. King Britt / Siim Nestor

    Index Scriptorium Estoniae

    Nestor, Siim, 1974-

    2005-01-01

    Popmuusikaüritustest: briti muusik Goldie esineb jungle-muusikaga Tallinnas 21. apr. klubis Privé, DJ Kevin Saunderson 22. apr. klubis Privé, laulja Nicole Willis 27. apr. BonBon Jazz Lounge'il klubis BonBon, Philadelphia muusik King Britt ja Eesti ansambel Broken Time Orchestra esitlevad oma heliplaate

  8. Calidad del servicio en el centro de servicio al contribuyente Nicolás de Piérola Sunat – Lima 2016

    OpenAIRE

    Vizcardo Fernández, Sara Ana de los Angeles

    2017-01-01

    La presente tesis titulada “Calidad del servicio en el centro de servicio al contribuyente Nicolás de Piérola - Sunat, Lima 2016” tiene por objetivo determinar la calidad del servicio que brinda el Centro de Servicio al Contribuyente de Nicolás de Piérola, centro perteneciente a la entidad pública Superintendencia Nacional de Aduanas y Administración Tributaria – SUNAT. El presente trabajo es de investigación descriptiva, corte transversal, no experimental y enfoque cuantita...

  9. Mathematical Concepts and Proofs from Nicole Oresme: Using the History of Calculus to Teach Mathematics

    Science.gov (United States)

    Babb, Jeff

    2005-01-01

    This paper examines the mathematical work of the French bishop, Nicole Oresme (c. 1323-1382), and his contributions towards the development of the concept of graphing functions and approaches to investigating infinite series. The historical importance and pedagogical value of his work will be considered in the context of an undergraduate course on…

  10. Visio intellectualis: Nicolás de Cusa y Schelling

    Directory of Open Access Journals (Sweden)

    Harald Schwaetzer

    2006-11-01

    Full Text Available Este trabajo pretende descubrir una proximidad sistemática entre el pensamiento de Nicolás de Cusa y el idealismo alemán, en particular, en torno a la noción de "visio intellectualis" entendida en el plano teórico del conocimiento. Pretende demostrar que lo que el Cusano piensa como "visión intelectual" acaba por no ser otra cosa que el "Yo que se contempla a sí mismo" ["selbst anschauende Ich"] en el que piensa Schelling y, así, que aquello que está en la base del pensamiento cusano y que se ha sido pensado a su manera en su tiempo, es lo mismo que fue mostrado en el tiempo de Schelling y a la manera de Schelling.

  11. Los avatares de la biblioteca privada de Nicolás Antonio (1687-1690

    Directory of Open Access Journals (Sweden)

    Luis ARIAS GONZÁLEZ

    2009-12-01

    Full Text Available Cuando fallece en Madrid Nicolás Antonio, el año de 1684, toda la fortuna que deja a sus herederos, son deudas; deudas a las que fundamentalmente le había llevado el afán investigador y publicista al que dedicó su vida entera. El único bien que le queda a sus deudos, será su colección particular de libros. Precisamente, lo que le sucede a la misma es el tema central de un documento manuscrito, inédito hasta ahora y que se encuentra depositado en la Biblioteca Universitaria Salmantina.

  12. Flora medicinal en San Nicolás, municipio de Malinalco, Estado de México

    OpenAIRE

    White-Olascoaga, Laura; Juan-Pérez, José Isabel; Chávez-Mejía, Cristina; Gutiérrez-Cedillo, Jesús Gastón

    2013-01-01

    Se determinaron aspectos sobre el hábitat, uso y función de los recursos vegetales utilizados en la medicina tradicional, en la comunidad de San Nicolás, municipio de Malinalco, ubicada al sur del Estado de México. De enero de 2010 a enero de 2011 se aplicaron entrevistas a 30 hombres y mujeres, de entre 20 y 60 años de edad. La observación directa y participativa permitió verificar la función y manejo de las plantas. Se registraron 165 especies correspondientes a 147 géneros y 70 familias de...

  13. Reflexiones sobre la actualidad del relativismo cultural: respuesta a Nicolás Sánchez Durá

    OpenAIRE

    Jacorzynski, Witold

    2013-01-01

    Este ensayo propone entablar una discusión con las tesis contenidas en el artículo de Nicolás Sánchez Durá, "Actualidad del relativismo cultural". En primer lugar, se analizan el etnocentrismo y el relativismo como dos respuestas éticas distintas al fenómeno de la diversidad cultural. En segundo lugar, se desarrollan la formulación del relativismo y el concepto de cultura propuestos por Sánchez Durá para analizarlos a la luz de la epistemología elaborada por el Wittgenstein tardío. En tercer ...

  14. The on-line low temperature nuclear orientation facility NICOLE

    International Nuclear Information System (INIS)

    Ohtsubo, T; Roccia, S; Gaulard, C; Stone, N J; Stone, J R; Köster, U; Nikolov, J; Veskovic, M; Simpson, G S

    2017-01-01

    We review major experiments and results obtained by the on-line low temperature nuclear orientation method at the NICOLE facility at ISOLDE, CERN since the year 2000 and highlight their general physical impact. This versatile facility, providing a large degree of controlled nuclear polarization, was used for a long-standing study of magnetic moments at shell closures in the region Z  = 28, N  = 28–50 but also for dedicated studies in the deformed region around A  ∼ 180. Another physics program was conducted to test symmetry in the weak sector and constrain weak coupling beyond V–A . Those two programs were supported by careful measurements of the involved solid state physics parameters to attain the full sensitivity of the technique and provide interesting interdisciplinary results. Future plans for this facility include the challenging idea of measuring the beta–gamma–neutron angular distributions from polarized beta delayed neutron emitters, further test of fundamental symmetries and obtaining nuclear structure data used in medical applications. The facility will also continue to contribute to both the nuclear structure and fundamental symmetry test programs. (paper)

  15. History and the "imagination of men's hearts" in Mike Nicol's Horseman

    Directory of Open Access Journals (Sweden)

    Ian-Malcolm Rijsdijk

    2011-10-01

    Full Text Available http://dx.doi.org/10.5007/2175-8026.2011n61p109 In light of the scattered nature of criticism regarding the work of South African author, Mike Nicol, this article surveys the transformation of Nicol’s novelistic style so as to better lluminate the representation and deployment of history in his third novel, Horseman (1994. South Africa’s political transformation not only offers a context for understanding the novel, but also provokes questions for the South African writer: how does the writer respond to the oppression of apartheid and the possibility of a new dispensation given the memory of such oppression? What forms best articulate that response? In the case of Horseman, how does one read the book’s pessimism against the backdrop of the first democratic elections? A consideration of Nicol’s greater body of work–his realist and more allegorical modes–points to a complicated relationship between the South African writer and the period of transition leading up to the 1994 elections.

  16. Nicolás Ruiz: la lucha contra el Estado y la restricción interna de derechos

    Directory of Open Access Journals (Sweden)

    Inés Castro Apreza

    2007-05-01

    Full Text Available Desde una perspectiva histórica, en este artículo se analiza el desarrollo político-electoral de Nicolás Ruiz, un municipio de los Valles Centrales de Chiapas; se pone el énfasis en el período que comienza en 1994, cuando sus habitantes cambian de opción política. Se muestra que es un caso paradigmático de una población mayoritaria con reivindicaciones frente al gobierno local y el Estado nacional, al tiempo que la asamblea de comuneros impone restricciones internas que limitan o anulan los derechos comunales y los derechos políticos de sus habitantes.

  17. Comunicado especial de la Alianza Bolivariana de los Pueblos de Nuestra América respaldando el triunfo de Nicolás Maduro en las elecciones presidenciales en Venezuela

    OpenAIRE

    Alianza Bolivariana para los Pueblos de Nuestra América - Tratado de Comercio de los Pueblos (ALBA-TCP)

    2013-01-01

    En el presente documento, los representantes de los países miembros del ALBA-TCP, expresan sus felicitaciones al candidato ganador de las elecciones en Venezuela, Nicolás Maduro y repudia los hechos de violencia ocurridos durante las elecciones en el país.

  18. Nicole Krauss’un Aşkın Tarihi Adlı Romanında Tarihi İzlekler

    OpenAIRE

    KALAY, Faruk

    2014-01-01

    Modern edebiyatta önemli Yahudi Amerikan yazarlarından olan Nicole Krauss Yahuditoplumundaki yabancılaşma, yalnızlık ve göç konularına değinir. Başarılı romanı olanAşkın Tarihi II. Dünya Savaşı süresince Holokost’a maruz kalan ve etkilerini hissedenYahudi karakterle ilgilidir. Tarihle bütünleşen bu karakterler gerçek hayattakiinsanlardan ve olaylardan esinlenmiştir. Krauss romanında postmodern teknikleri dekullanır. Örneğin iç içe anlatım tekniği okuyucuya romanın kurgusal mı yoksa gerçek mio...

  19. Rezension zu: Nicole C. Karafyllis, Gotling Ulshöfer: Sexualized Brains. Cambridge u.a.: MIT Press 2008

    Directory of Open Access Journals (Sweden)

    Sigrid Schmitz

    2009-07-01

    Full Text Available In der Auseinandersetzung um geschlechtliche Normierungen spielt die moderne Hirnforschung eine wirkmächtige und inzwischen disziplinenübergreifende Rolle. Nicole Karafyllis und Gotlind Ulshöfer stellen in diesem Sammelband mit Beiträgen aus Neurowissenschaft, Psychologie, Soziologie, Kulturwissenschaft und Philosophie ein multiperspektivisches Diskursfeld zu der Frage vor, ob die Emotionale Intelligenz (EI als erstrebenswerte Fähigkeit die klassische Kodierung in männliche Rationalität bzw. weibliche Emotionalität dekonstruieren und ein emanzipatorisches Potential entgegen gesellschaftlichen Hierarchisierungen entfalten kann. Viele Aspekte, Verbindungen zwischen den Diskurssträngen und wechselseitige Beeinflussungen, aber auch disziplinäre Eingrenzungen werden sichtbar, die eine kritische Fortführung des hier angestoßenen Dialogs notwendig machen.

  20. El converso sevillano Nicolás Martínez de Medina (o de Sevilla, contador mayor de Castilla. Apuntes para una biografía = Nicolás Martínez Medina (or de Sevilla, Sevilian Converso and Chief Accountant of Castile. Notes for a Biography

    Directory of Open Access Journals (Sweden)

    Isabel Montes Romero-Camacho

    2014-06-01

    Full Text Available A partir de la conquista de Sevilla, en 1248, fueron muchos los judíos, primero, y los conversos, después, que llegaron a ocupar una posición preeminente, tanto en la ciudad, como en la corte, desempeñando, casi siempre, importantes oficios, al servicio de la hacienda real castellana, en una secuencia prácticamente ininterrumpida que va desde Alfonso X (1252-1284 hasta la nueva dinastía Trastámara. Uno de estos importantes conversos fue Nicolás Martínez de Medina (o de Sevilla, cuya actuación pública se desarrolló durante los reinados y a la sombra de los primeros Trastámara, desde Enrique II (1369-1379 hasta Juan II (1406-1454 y que, tras una brillante carrera en Sevilla y en la corte, llegaría a ser contador mayor de Castilla y, por tanto, uno de los personajes más influyentes de su época.After the conquest of Seville in 1248, many Jews and later «Conversos» played a prominent role both in the city and in the Court. They occupied significant positions at the service of the Spanish royal treasury almost uninterruptedly from the reign of Alfonso X (1252-1284 to that of the new Trastámara dynasty. One of these important «Conversos» was Nicolás Martínez de Medina (or de Sevilla, who held public positions under the reigns of the first Trastámara kings, from Enrique II (1369-1379 to Juan II (1406-1454. After a brilliant career in Seville and in the Court, he would become chief accountant of Castile and, consequently, one of the most influential individuals of his time.

  1. El patrimonio rupestre de Gran Canaria. Los grabados de la Montaña de Las Vacas (Aldea de San Nicolás

    Directory of Open Access Journals (Sweden)

    Ernesto Martín Rodríguez

    2013-11-01

    Full Text Available Se presentan varias estaciones rupestres inéditas para la investigación, localizadas en el curso de los trabajos arqueológicos llevados a cabo en la Montaña de Hogarzales (Aldea de San Nicolás, Gran Canaria en torno a la explotación de la obsidiana por las comunidades prehistóricas de la isla.One presents rock art unpublished stations for the investigation, located in the course of the archaeological works led to end in Hogarzales's mountain (Village of San Nicolas, Great Canary concerning the exploitation of the obsidian for the prehistoric communities of the island.

  2. La musa que tose. Nicolás Olivari y una poética de vanguardia en la literatura rioplatense de la década de 1920

    Directory of Open Access Journals (Sweden)

    Sara Amalia Bosoer

    2014-03-01

    This article analyses in La musa de la mala pata (1926, the second book of poetry of Nicolás Olivari (1900-1966, the formulation of a poetics of vanguard in the Río de la Plata literary context. From what we call a poetic of cough, in his poems we follow the formulation of a poetic language that seeks to secede from the modernist notions of poetic musicality, proposes a demystification of poetic language and move towards a conception of language that interrogates the referentiality.

  3. El sistema westfaliano: un análisis desde la teología política de Nicolás Gómez Dávila

    OpenAIRE

    Molina, Tomás Felipe

    2016-01-01

    Resumen En este artículo, se quieren analizar las características principales del sistema westfaliano a partir de la teología política que Nicolás Gómez Dávila desarrolla en Textos I. Principalmente, se intentará mostrar que los Estados westfa- lianos toman los atributos de Dios y sustituyen a la divinidad en el papel que tenía en la Edad Media: reclaman para sí mismos la soberanía y la fundamentación axiológica y ontológica de los elementos del sistema. A partir de lo anterior, el artículo p...

  4. A Kantian argument for a duty to donate one's own organs. A reply to Nicole Gerrand.

    Science.gov (United States)

    Merle, J C

    2000-01-01

    Nicole Gerrand is right to criticize Munzer for not connecting a person's dignity to the "capacity to exhibit humanity by acting rationally." However, connecting these does not mean that they are one and the same concept. Gerrand fails to make two distinctions that are decisive in the context of Kant's ethics. First, she does not distinguish between vital organs, integral organs and mere "accumulations", each of which requires a specific moral argument. Second, she does not distinguish between human rational nature in itself, or the capacity to have free will, and the possibility of action rationally, or freedom of choice. Having drawn these distinctions, I argue that Kant's own principles fully allow certain kinds of organ transplants such as blood, skin and marrow transplants from living bodies as well as the transplantation of both vital organs and essential organs from fresh corpses. In fact, Kant's own moral principles should make of these an enforceable duty of right. Unlike Gerrand, then, I think that the question of whether or not donors should be paid--and the patient should pay--is a key issue even in a Kantian context.

  5. Un escritor ante las instituciones: el caso de Nicolás Fernández de Moratín (1737-1780

    Directory of Open Access Journals (Sweden)

    Philip DEACON

    2009-11-01

    Full Text Available RESUMEN: En la España dieciochesca, cuando el mercado editorial no se había desarrollado lo suficiente para que un hombre de letras viviera sólo de su pluma, el escritor tenía que aprender a navegar por el complejo mundo institucional. El peso de entidades como la monarquía, la nobleza y la Iglesia seguía siendo grande, pero el espíritu renovador de la época dio lugar a nuevos organismos como las academias, sociedades económicas, e incluso instituciones menos definidas como la prensa y la tertulia cultural. Este artículo traza la carrera de Nicolás Fernández de Moratín, describiendo cómo se enfrentó con esas entidades y precisando cómo influyeron en sus escritos. Algunas instituciones como las educativas, profesionales o eclesiásticas conformaron las actividades del escritor tanto en el terreno ideológico como en el estilístico; otras, como en el caso de Moratín la Sociedad Económica Matritense, abren nuevas perspectivas para dar resultados literarios singulares al producirse una confluencia entre formas tradicionales y temas nuevos.ABSTRACT: In eighteenth-century Spain, where the literary world was insufficiently developed to allow authors to live by the pen, writers had to learn to negotiate the complex ways of established institutions. The prevailing influence of the monarchy, nobility and Church was great, but the spirit of renewal evident during the period gave rise to new organizations such as the royal academies, economic societies and less clearly identifiable institutions such as the press or the cultural club. The present article outlines the career of Nicolás Fernández de Moratín, demonstrating how the author negotiated these organizations and how they influenced his writings. Some institutions, like those belonging to the educational, professional and ecclesiastical worlds, influenced the writer both in an ideological and stylistic sense; others, as in Moratín’s case the Madrid Economic Society, provided an

  6. La reforma militar y el gobierno de Nicolás de Piérola. El Ejército moderno y la construcción del Estado peruano

    OpenAIRE

    Velásquez Silva, David Víctor

    2013-01-01

    La presente investigación busca dar cuenta de la reforma del Ejército peruano iniciada en el segundo gobierno de Nicolás de Piérola (1895-1899), vinculando su ejecución con los procesos de construcción del Estado peruano. Esta reforma acabó con los ejércitos caudillistas decimonónicos, transformando a la institución castrense en un ejército nacional, profesional y burocrático. A través de la concentración de una serie de competencias y recursos militares distribuidos en los diferentes actores...

  7. Antero-posterior patterning of the vertebrate digestive tract: 40 years after Nicole Le Douarin's PhD thesis.

    Science.gov (United States)

    Grapin-Botton, Anne

    2005-01-01

    This review is dedicated to the work on chick digestive tract organogenesis that Nicole Le Douarin performed as a PhD student under the direction of Etienne Wolf. I discuss how she laid the grounds for future work by establishing fate maps at somitic stages, by describing morphogenetic movements between germ layers and by pointing to signaling events between endoderm and mesoderm. Her inspiring work was extended by others, in particular at the molecular level, leading to a better understanding of antero-posterior patterning in the digestive tract. Antero-posterior patterning of endoderm is initiated at gastrulation when future anterior and posterior endoderm ingress at different times and accordingly express different genes. Plasticity is however maintained at somite stages and even later, when organ primordia can be delineated. There is a cross-talk between endoderm and mesoderm and the two layers exchange instructive signals that induce specific antero-posterior identities as well as permissive signals required for organogenesis from previously patterned fields. Recent experiments suggest that several signaling molecules involved in neural tube antero-posterior patterning are also instrumental in the digestive tract including retinoic acid and FGF4.

  8. Las tics y la calidad de servicios en la biblioteca Camilo Arévalo Govea de la Unidad Educativa Nicolás Infante Díaz del cantón Quevedo

    OpenAIRE

    Contreras Narváez, Mónica María

    2016-01-01

    Con la existencia de aproximadamente 5000 libros y después de 48 años de funcionamiento la Biblioteca “Camilo Arévalo Govea” de la Unidad Educativa Nicolás Infante Díaz con tres administradores desde su origen presenta una serie de dificultades para la atención de los estudiantes de las tres jornadas: matutina, vespertina y nocturna del plantel. Sus textos se encuentran organizados con un proceso de catalogación universal basado en un sistema clasificación decimal DEWEY y además a pesar de te...

  9. Valuación de la calidad urbano-ambiental. Una modelación hedónica: San Nicolás de los Garza, México

    Directory of Open Access Journals (Sweden)

    Jesús Manuel Fitch Osuna

    2013-01-01

    Full Text Available En esta investigación se aborda la teoría de la formación espacial de valores inmobilia - rios (vivienda en el municipio de San Nicolás de los Garza, México. Ese ámbito se en - cuentra inmerso en una dinámica metropolitana, de ahí que se evalúe el proceso inmo - biliario frente a las fuerzas centrales y periféricas que generan el crecimiento y el ciclo de vida urbano e inmobiliario, así como la calidad urbana ambiental. El resultado es un modelo de precios hedónicos que definen los atributos que explican con mayor grado de significancia el cambio en el valor del suelo. Todo ello coadyuva a la implementación de una política de suelo.

  10. Nicole Matthews & Nickianne Moody, eds., Judging a Book by Its Cover: Fans, Publishers, Designers, and the Marketing of Fiction.

    Directory of Open Access Journals (Sweden)

    Thomas Van Parys

    2010-01-01

    Full Text Available

     

    Judging a Book by Its Cover: Fans, Publishers, Designers, and the Marketing of Fiction

    Nicole Matthews & Nickianne Moody, eds.,

     

    Judging a Book by Its Cover: Fans, Publishers, Designers, and the Marketing of Fiction. Aldershot/Burlington: Ashgate, 2007.

    ISBN: 978-0-7546-5731-6

  11. Maíz, potencial productivo y seguridad alimentaria: el caso de San Nicolás de Los Ranchos, Puebla-México

    Directory of Open Access Journals (Sweden)

    Miguel A. Damián Huato

    2016-01-01

    Full Text Available Se expone un modelo tecnológico para aumentar el potencial productivo de maíz de secano, validado con productores de San Nicolás de los Ranchos Puebla-México. Se calculó el Índice de Apropiación de Tecnologías Radicales (IATR y el Grado de Empleo de Tecnologías Progresivas (GETP; se agruparon a los productores según su rendimiento para diseñar el modelo tecnológico y se estimó la seguridad alimentaria real y potencial. Se encontró que: en el manejo de maíz interaccionan innovaciones radicales y progresivas imperando las segundas; no hay relación directa entre el IATR y rendimientos, pero sí con el GETP; que 29% de los productores son eficientes; el 29% de los productores no poseen seguridad alimentaria y que si los productores de bajo y medio potencial productivo, aplicaran el patrón tecnológico de los productores eficientes, los rendimientos aumentarían, en promedio un 157% y 38%, respectivamente.

  12. Liber Nycholay. La leyenda de Mahoma y el cardenal Nicolás

    Directory of Open Access Journals (Sweden)

    González Muñoz, Fernando

    2004-06-01

    Full Text Available The aim of this paper is to offer a critical edition, with translation and commentary, of Liber Nycholay, an anonymously authored Latin text of Italian origin, probably Roman, which could be dated back to the second half of the thirteenth century. Liber Nycholay presents a curious version of the legend of Mahoma, according to which he would have originally been a Roman cardinal called Nicholaus, whose frustrated ambitions to papacy led him to found a new religion in revenge. The text combines data on the Islamic doctrines and practices with anachronisms and legendary details further verified in other mediaeval texts. This edition has been drawn from the two existing manuscripts of the work, the Parisinus BN lat. 14503 and the Vaticanus Reginensis Latinus 627.

    El presente trabajo ofrece una edición crítica, con traducción y estudio, del Liber Nycholay, un texto latino anónimo de procedencia italiana, probablemente romana, que puede datarse en la segunda mitad del siglo XlIl. El Liber Nycholay presenta una curiosa versión de la leyenda de Mahoma, según la cual éste habría sido en origen un cardenal romano llamado Nicolás que, frustrado en sus ambiciones por acceder al papado, fundó una nueva religión a modo de venganza. El texto combina datos exactos sobre las doctrinas y prácticas islámicas con anacronismos y detalles legendarios atestiguados también en otros textos medievales. La edición se ha confeccionado a partir de los dos manuscritos que transmiten la obra, el Parisinus BN lat. 14503 y el Vaticanus Reginensis Latinus 627.

  13. Conceptos básicos sobre terremotos y las causas que lo originan, proyecto de prevención y mitigación del riesgo en el colegio Nicolás Gómez Dávila I.E.D

    OpenAIRE

    Hernández Ortiz, Gerardo

    2012-01-01

    El presente trabajo, es un estudio del conocimiento que tienen los estudiantes de ciclo III en el Colegio Nicolás Gómez Dávila, sobre el concepto de terremoto y las causas que lo producen, lo que permitió fortalecer el Plan Escolar de Gestión del Riesgo institucional. El proceso se desarrolló en tres fases: En la primera se realizó la fundamentación teórica partiendo desde los componentes legales, los cuales establecen la importancia de los planes de gestión de riesgo en Colombia, seguido...

  14. Flora medicinal en San Nicolás, municipio de Malinalco, Estado de México

    Directory of Open Access Journals (Sweden)

    Laura White-Olascoaga

    2015-08-01

    Full Text Available Se determinaron aspectos sobre el hábitat, uso y función de los recursos vegetales utilizados en la medicina tradicional, en la comunidad de San Nicolás, municipio de Malinalco, ubicada al sur del Estado de México. De enero de 2010 a enero de 2011 se aplicaron entrevistas a 30 hombres y mujeres, de entre 20 y 60 años de edad. La observación directa y participativa permitió verifi car la función y manejo de las plantas. Se registraron 165 especies correspondientes a 147 géneros y 70 familias de plantas vasculares. Las especies utilizadas en la medicina tradicional se agruparon en 13 clases o categorías de acuerdo con el tipo de enfermedad en que se utilizan. Las categorías de plantas medicinales que mostraron las mayores frecuencias de utilización se relacionan con el tratamiento de enfermedades del aparato digestivo, aparato respiratorio, enfermedades asociadas con la nutrición y sistema endócrino, además de las referidas como síndromes de filiación cultural.Las plantas medicinales se presentaron en dos diferentes hábitat; 45.4% son especies pertenecientes a la flora viaria y el 54.5% prosperan en agroecosistemas familiares, llamados localmente huertos o solares. Aproximadamente un tercio de las especies eran cultivadas y el resto silvestres. Tres cuartos de las especies presentan una distribución natural en América, y las demás han sido introducidas de ultramar. Los datos muestran que el mayor número de especies utilizadas para fines medicinales se encuentran en los huertos. Esto implica nuevos retos debido a que los huertos familiares tradicionales están siendo utilizados para fines diversos, como la construcción de viviendas o establecimientos comerciales, ocasionando pérdida de germoplasma in situ y en consecuencia pérdida de la biodiversidad en este territorio del subtrópico mexicano.

  15. Diversificación productiva en el suelo de conservación de la ciudad de México. Caso San Nicolás Totolapan

    Directory of Open Access Journals (Sweden)

    V. Sophie Ávila-Foucat

    2012-01-01

    Full Text Available El objetivo es describir la diversificación de ingresos no agropecuarios en el Suelo de Conservación de la ciudad de México y en particular mostrar los impactos en el capital natural, social y económico de la diversificación productiva sustentable en San Nicolás Totolapan, enfatizando el papel de la Unidad de Manejo para Conservación de la Vida Silvestre ((para cuyo uso abreviado se emplea UMA, que significa Unidad de Manejo Ambiental. Se efectuaron entrevistas a profundidad a miembros del parque y a funcionarios de gobierno. Los resultados muestran que la UMA ha generado impactos positivos en la especie manejada, pero la conservación del hábitat corresponde a la reserva comunitaria. El impacto económico es positivo, pero insuficiente y el social es positivo porque ha incentivado la organización de la comunidad y una participación cada vez mayor de los miembros del ejido. La diversificación productiva sustentable en la zona rural del suelo de conservación tiene un impacto positivo que puede contribuir a retener la mancha urbana.

  16. SWASV speciation of Cd, Pb and Cu for the determination of seawater contamination in the area of the Nicole shipwreck (Ancona coast, Central Adriatic Sea).

    Science.gov (United States)

    Annibaldi, Anna; Illuminati, Silvia; Truzzi, Cristina; Scarponi, Giuseppe

    2011-12-01

    The study reports for the first time on the heavy metal contamination of the waters surrounding a shipwreck lying on the sea floor. Square wave anodic stripping voltammetry has been used for a survey of the total and dissolved Cd, Pb and Cu contents of the seawater at the site of the sinking of the Nicole M/V (Coastal Adriatic Sea, Italy). Results show that the hulk has a considerable impact as regards all three metals in the bottom water, especially for the particulate fraction concentrations, which increased by factors of ≈ 9 (Cd), ≈ 3 (Pb) and ≈ 5 (Cu). The contaminated plume extended downstream for about 2 miles. Much lower contamination was observed for dissolved bottom concentrations; nevertheless Pb (0.56 ± 0.03 nmol/L) is higher than the Italian legal limits established for 2015 and Cd (0.23 ± 0.03 nmol/L) is very close the limit of Cd will be exceeded if the hulk is not removed. Copyright © 2011. Published by Elsevier Ltd.

  17. Un pensador Aristocrático en los Andes: Una mirada al pensamiento de Nicolás Gómez Dávila.

    Directory of Open Access Journals (Sweden)

    Mauricio Galindo Hurtado.

    2000-06-01

    Full Text Available Sobresaliente en el panorama intelectual colombiano es la figura de Nicolás Gómez Dávila. Este escritor sabanero es tal vez la única voz que, en forma explicita y magistral, se propuso desmenuzar el pensamiento occidental asumiendo la postura del reaccionario. Gómez Dávila deja, al morir, un libro en cinco etapas, colección de aforismos qúe insiste en llamar escolios, en los cuales discurre sobre la filosofía, la moral, la estética, la historia y la literatura de más de dos mil años de civilización grecolatina. La obra de Gómez Dávila posee la convicción dogmática del reaccionario que condena con juicios enfáticos las glorias del hombre "moderno". Hay allí ecos de una visión hispánica de Contra Reforma que influyó no poco en buena parte de las elites colombianas. Mas es también un llamado a la sensibilidad y a la belleza, un recordatorio que más allá de un conocimiento racional y científico, está la dimensión de la persona humana que ningún sistema puede abarcar. Férreo defensor de un libre albedrío enmarcado en un exigente universo moral, su voz incita al despliegue máximo de la inteligencia, inigualable herramienta para alzar vuelo sobre realidades pedestres.

  18. Activities of the senspol and NICOLE network concerning field investigation at contaminated sites

    Energy Technology Data Exchange (ETDEWEB)

    Ree, C.C.D.F. von [GeoDelft, AB Delft (Netherlands); Alcock, S. [Cranfield Univ. of Silsoe, Bedfordshire (United Kingdom)

    2003-07-01

    At a European level several networks can be identified aimed at developments and exchange of knowledge relevant to sustainable management of the subsurface. Based on the common interests in the field of site characterisation and monitoring the SENSPOL and NICOLE networks have established links resulting in cooperation in several project-activities. In this presentation two projects will be addressed: - Seville technicalmeeting (Aznacollar mining site). - Bridging gaps between sensor developers and (end) users in a pragmatic approach (GAPS-project). The goal of the Seville technical meeting was to apply the latest sensing technologies at a site contaminated by metal mining activities, to properly evaluate the advances and limitations in the monitoring of contaminated sites for sustainable land management and to determine further steps to commercial exploitation. Some 17 different instruments have been brought including: - Electrochemical sensors using different forms of anodic stripping voltammetry and constant current chronopotentiometry combined with several types of screen printed electrodes. - An amperometric biosensor using screen printed electrodes, which measures toxicity by inhibition effects on urease and its sensitive to Hg(II), Ag(I), Cu(I) and to a lesser extent to Pb(II), Zn(II) and Cd(II) and a selectrochemical DNA biosensor measuring overall toxicity. - A luminescent bacterial sensors for measuring the bioavailable fraction of Cd, Pb, Zn, Cu, As, and Hg, and a bioluminescent fiber optic sensor for Hg and As. - Toxicity testing instruments (Checklight 'ToxScreen Multi-Shot Test, ToxAlert {sup registered} 100 and ToxAlert {sup registered} 10) - A fieldprobe for pH, EC, TDS measurement - A lead automatic analyser AQUAMET using a ion-selective electrode. - Pulse-neutron borehole device in which interaction of neutrons with the surrounding medium can be used to monitor changes. In a two-day field session on the mining site participants were provided

  19. Kas keegi vajab neid raamatuid? / Jaanika Palm

    Index Scriptorium Estoniae

    Palm, Jaanika, 1973-

    2001-01-01

    Rets. rmt. : Müürsepp, Mare. Kolm põrsakest. Punamütsike : muinasjutu-kirjavihik 5-aastastele lastele. 1 vihik / jutustanud, luuletanud ja ülesanded välja mõelnud Mare Müürsepp. Tallinn : Ilo, 2000. Sari "Muinasjutt õpetab" : Hans ja Grete / [idee: Nicole Lenaerts-Viroux. Tallinn] : Egmont Estonia, 2001; Hunt ja seitse kitsetalle / [idee: Nicole Lenaerts-Viroux. Tallinn] : Egmont Estonia, 2000; Lumivalgeke ja seitse pöialpoissi / [idee: Nicole Lenaerts-Viroux. Tallinn] : Egmont Estonia, 2001; Pöial-Liisi / [idee: Nicole Lenaerts-Viroux. Tallinn] : Egmont Estonia, 2000

  20. Uso medicinal de las plantas por los otomíes del municipio de Nicolás Flores, Hidalgo, México

    Directory of Open Access Journals (Sweden)

    A. Sánchez-González

    2008-01-01

    Full Text Available El conocimiento de las plantas medicinales por los otomíes (hñähñü de Nicolás Flores, Hidalgo se ha mantenido a través de las generaciones. La influencia de la medicina alópata está restringida principalmente a la prevención de enfermedades como poliomielitis, sarampión, viruela y paludismo. La medicina tradicional es más viable ante las condiciones socioeconómicas, fisiográficas y culturales en esta región. El objetivo de este estudio fue identificar las especies de plantas que utilizan los hñähñü con fines medicinales, el tipo de enfermedades que se tratan y la afinidad geográfica de las mismas. El trabajo de campo consistió en la realización de entrevistas abiertas a los pobladores del municipio y en la colecta de ejemplares en diferentes unidades "etnoecológicas". Se reporta el uso medicinal de 112 especies en el tratamiento de afecciones como susto, dolor de estómago, dolor del riñón, diarrea, fiebre, mal de ojo, entre otras. Aunque la mayoría de los habitantes conoce el uso medicinal de algunas plantas, los ancianos son más cultos, en la sabiduría hñähñü, como la de otras etnias de México, el pensamiento mágico-religioso forma parte de su cosmovisión y consideran la dualidad frío-caliente para el tratamiento. La gama de enfermedades que se presume curan las plantas registradas es muy amplio, desde la gripe hasta el cáncer. El 75 % de las especies utilizadas por esta etnia son nativas del Continente Americano, principalmente de México y Centroamérica (39 %, lo que sugiere que el acervo botánico básico tradicional hñähñü aún es vigente.

  1. Mylonites: Lessons from Eriboll

    OpenAIRE

    White, S.H.

    2010-01-01

    Eriboll has been an important area in understanding the geology and structure of the NW Highlands of Scotland. It came to prominence during the Highland Controversy between Nicol and Murchison in the 1850s. Nicol recognized a major regional, or grand, dislocation (the Moine Thrust Zone) at Eriboll whereas Murchison denied its existence. An important element in the resolution of the controversy was the repeated observation of a distinctive schistose rock that often marked Nicol's dislocation. ...

  2. Identification and Validation of Established and Novel Biomarkers for Infections in Burns

    Science.gov (United States)

    2016-10-01

    Dr. Nicole Enman, Science Officer, CDMRP, Phone : (301) 619-7040, Email: nicole.m.enman.ctr@mail.mil Overlap: None 1 KL2 TR001441-01 (Ameredes...Science Officer, CDMRP, Phone : (301) 619-7040, Email:nicole.m.enman.ctr@mail.mil Overlap: None ***New Award*** UL1TR001439 (Tyler) 04/01/16-03/31...Cunningham) 09/01/13-04/30/18 5% NIH/NIDA $136,017 Translational Addiction Sciences Center, Core A Goals: The Translational Addiction

  3. Sobre os céus e as marés do Pacífico: as observações astronômicas do jesuíta Nicolás Mascardi (Chile, século XVII

    Directory of Open Access Journals (Sweden)

    Eliane Cristina Deckmann Fleck

    2014-12-01

    Full Text Available A atuação da Companhia de Jesus na América espanhola e portuguesa constitui-se em tema de várias investigações e obras, nas quais merece destaque a dedicação de seus religiosos ao ensino e à catequese. Alguns membros da Ordem, no entanto, se dedicaram, também, a observações de fenômenos naturais, da fauna e da flora nativas e, ainda, a aspectos da geografia dos territórios em que atuaram, legando-nos uma série de estudos informados através de cartas, relatórios ou obras. Nosso propósito neste artigo é o de apresentar e analisar os registros que o padre jesuíta italiano Nicolás Mascardi fez de suas observações astronômicas e, em especial, do estudo que realizou sobre as marés do arquipélago de Chiloé durante os anos em que atuou na então Vice-Província Jesuítica do Chile, no século XVII.

  4. Images in medicine

    African Journals Online (AJOL)

    ebutamanya

    2015-10-12

    Oct 12, 2015 ... 1Department of Neonatology, Charles Nicole Hospital, Tunis El Manar University, Tunis, Tunisia. &Corresponding author: Emira Ben Hamida, Department of Neonatology, Charles Nicole Hospital, Tunis El Manar University, Tunis, Tunisia. Key words: Harlequin color change, dermatology, neonate, preterm.

  5. Mylonites: Lessons from Eriboll

    NARCIS (Netherlands)

    White, S.H.

    2010-01-01

    Eriboll has been an important area in understanding the geology and structure of the NW Highlands of Scotland. It came to prominence during the Highland Controversy between Nicol and Murchison in the 1850s. Nicol recognized a major regional, or grand, dislocation (the Moine Thrust Zone) at Eriboll

  6. Recreating Rocks

    DEFF Research Database (Denmark)

    Posth, Nicole R

    2008-01-01

    Nicole Posth and colleagues spent a month touring South African rock formations in their quest to understand the origin of ancient iron and silicate layers.......Nicole Posth and colleagues spent a month touring South African rock formations in their quest to understand the origin of ancient iron and silicate layers....

  7. Using Formative Assessment to Facilitate Learner Self-Regulation: A Case Study of Assessment Practices and Student Perceptions in Hong Kong

    Science.gov (United States)

    Jing Jing, Ma

    2017-01-01

    One of the key aims of formative assessment in higher education is to enable students to become self-regulated learners (Nicol & Macfarlane-Dick, 2006). Based on Nicol and Macfarlane-Dick's (2006) framework, this exploratory study investigates which formative assessment practices proposed by them were used by one college EFL writing teacher to…

  8. La expedición del padre Nicolás Mascardi a la Patagonia: una experiencia sobre las posibilidades y los límites del conocimiento en el siglo XVII

    Directory of Open Access Journals (Sweden)

    Constanza Acuña Fariña

    2015-03-01

    Full Text Available En 1670 el jesuita Nicolás Mascardi (Sarzana 1624, Río Deseado 1674 dirigió la refundación de la misión de Nahuel Huapi. Siguiendo los pasos de su antecesor Diego de Rosales quiso establecer una reducción indígena para puelches, poyas y tehuelches, punto de partida de misiones “volantes” hasta el estrecho de Magallanes. A partir del estudio de las cartas que Mascardi envió a su maestro Athanasius Kircher desde el sur de Chile, el presente trabajo pretende analizar cómo confluyen en el proyecto del jesuita italiano la imaginación barroca, la mentalidad y las prácticas del siglo XVII, para tratar de entender por qué su plan se precipitó bajo los acontecimientos históricos que marcaron la deriva de su proyecto misionero y su temprana muerte a manos de los tehuelches. El encuentro de concepciones culturales, las estrategias de dominio geográfico y la defensa de mundos simbólicos, son los hilos conductores que guían las principales preguntas y supuestos de este trabajo. La misión de Mascardi constituiría un ejemplo para comprender bajo qué principios y contradicciones se impuso el concepto de civilización en el proceso de colonización americana.

  9. Mobilising Spaces of Agency through Genealogies of Race and Gender: Issues of Indigeneity, Marginality and Schooling

    Science.gov (United States)

    Keddie, Amanda; Williams, Nicole

    2012-01-01

    This article presents data from a case study of a non-traditional secondary school for Indigenous girls located in a suburban area of Queensland (Australia). The focus is predominantly on the identity and practices of Nicole who is one of the school's teachers. Nicole's identity as an Indigenous woman and teacher and the school's approach to…

  10. Ideas Previas Acerca de “Evolución y Su Relación con la Genética” en Estudiantes de Grado Noveno del Colegio Nicolás Esquerra

    Directory of Open Access Journals (Sweden)

    Sergio Alejandro Peláez Plazas

    2015-12-01

    Full Text Available Como primera experiencia didáctica, en este trabajo se muestran las ideas previas que construyen 10  estudiantes de noveno grado del colegio Nacional Nicolás Esguerra acerca del proceso de evolución, las cuales se encuentran relacionadas con algunos conceptos que aborda la genética. Los datos fueron recogidos por medio de una encuesta de pregunta abierta y un dibujo en base al método cualitativo, con el fin de conocer la comprensión que los estudiantes tienen acerca de la evolución y  los conceptos mencionados en sus explicaciones, entre los cuales se encontraron: adaptación, ADN y código genético,  relacionando en estos el tiempo como factor de cambio. Estas ideas se organizaron en tres categorías  (Comprensión de Procesos evolutivos basados en variabilidad y selección natural e Ideas relacionadas al catastrofismo como factor promotor de especiación. Entre estas, la mayoría de los alumnos hace alusión a cambios en el ciclo de vida y desarrollo, y no como un proceso a nivel histórico y constante en las poblaciones. En cuanto a la comprensión del ADN, el gen y su relación con las especies, no hay claridad con respecto a la expresión de caracteres desde  la información que se expresa en las proteínas. Por consiguiente, se infiere que las ideas encontradas están poco articuladas  ya que ellos no las logran conectar de forma apropiada en sus respuestas.

  11. Los cambios en la representación de la estructura capitalista y su incidencia en la cotidianeidad de la masa marginal entre mediados del siglo XX y la actualidad. El caso de los habitantes de una villa de emergencia de la ciudad de San Nicolás

    Directory of Open Access Journals (Sweden)

    Cánepa Moretti, Elizabeth

    2013-09-01

    Full Text Available El presente trabajo se propone analizar los cambios operados en la forma de representación de la estructura capitalista y de su incidencia en la cotidianeidad de los habitantes de Villa Tranquila, de la ciudad de San Nicolás, a partir de los años de reconversión neoliberal del Estado argentino, sobre todo en la década del ’90.El asentamiento en el que se desarrolla este estudio tiene una historia muy particular, puesto que hace décadas formaba parte de un barrio mucho más grande, llamado Villa Pulmón, nacido a partir del asentamiento de personas provenientes del norte del país, que encontraron empleo en la construcción de la empresa siderúrgica SOMISA. A finales de la última dictadura militar, Villa Pulmón es desalojada, resistiendo sólo el pequeño barrio donde centraremos nuestro estudio, ocupado por aproximadamente 40 familias. En el gran terreno que antes ocupaba la Villa Pulmón se instaló el santuario de la Virgen María, ya en los primeros años de la democracia. Durante el gobierno de Carlos Menem, SOMISA fue privatizada y San Nicolás perdió en parte su perfil industrial para convertirse en una ciudad orientada a los servicios, con gran influencia del turismo religioso al santuario.Este trabajo, además, recoge la memoria construida en Villa Pulmón, referenciada en un Estado nacional con un proyecto industrialista y una presencia fuerte en la gestión de sectores estratégicos de la economía, para contraponerlo con la realidad de los habitantes actuales de Villa Tranquila, entre quienes encontramos las características propias de los sectores urbano-marginales de la actualidad, relacionadas con la desafiliación del mundo del trabajo formal y de otras instituciones que antes marcaban el pulso de la clase trabajadora, como la escuela pública, los sindicatos, etc. Las fuentes utilizadas son, entrevistas a habitantes de Villa Tranquila de distintas edades: mujeres adultas, generalmente madres, y adolescentes varones de

  12. On the Treatment of Authors, Outliers, and Purchasing Power Parity Exchange Rates.

    Science.gov (United States)

    Jaeger, Richard M.

    1993-01-01

    Ruth Stott violates canons of scholarly debate by attacking author's October 1992 "Kappan" article on world-class academic standards. Average class size predicted only 10% of variation in 13 year-olds' mean mathematics scores in 14 nations supplying reasonable comprehensive sampling frames for International Assessment of Academic…

  13. Engineering from the Sea: Establishing How Australian Army Engineers Fit into Australia’s Amphibious Concept

    Science.gov (United States)

    2011-03-16

    STUDIES MAJOR M.D. SCOTT AUSTRALIAN ARMY AY 10-11 Oral Defense Committee Member: Dr. John W. Gordon , Ph.D., Professor ofNational Security App...equivalent to a Private. 9 Ronald Ramsay McNicoll, The Royal Australian Engineers 1902 to 1919: The Second Volume of the History of the Royal...Special Collections Branch, Library of the Marine Corps, WWII Marianas Islands Collection, Box 4, Folder 2; and Ronald Ramsay McNicoll, The Royal

  14. Evaluación de daños y actuaciones de rehabilitación en la iglesia de San Nicolás de Eduardo Torroja (Gandía, 1962

    Directory of Open Access Journals (Sweden)

    Serrano-Lanzarote, B.

    2016-03-01

    Full Text Available The church of San Nicolas in Gandia (1962, is the posthumous work of Eduardo Torroja Miret, engineer, in collaboration with Gonzalo Echegaray Comba, architect. The temple is characterized by its unique structure: two folded sheets of post-tensioned concrete, supported on the side walls, with 29 meters span. In 1996, the detection of cracks in the concrete and spalling, made it advisable an inspection and evaluation of the damages detected in the building, mostly caused by the corrosion of reinforcement concrete, and concluded by recommending repair them. This paper explains the structural system of the temple, describes the identified damages in the structure, exposes the refurbishment project and displays the works executed during the intervention. The work was completed just in time for the 50th anniversary of its construction in 2012.La iglesia de San Nicolás de Gandía (1962, es la obra póstuma del ingeniero Eduardo Torroja Miret, en colaboración con el arquitecto Gonzalo Echegaray Comba. El templo se caracteriza por su singular estructura: dos láminas plegadas de hormigón armado postesado, apoyadas en los testeros, salvando una luz de 29 m. En el año 1996, la detección de fisuras en el hormigón y desprendimientos de recubrimientos de las armaduras, hicieron aconsejable una inspección y evaluación exhaustiva de las lesiones que presentaba el edificio, mayormente producidas por la corrosión de las armaduras del hormigón, y que concluyó recomendando la reparación de las mismas. El presente trabajo explica el sistema estructural del templo, describe los daños detectados en la estructura, expone el proyecto de rehabilitación que se elaboró y muestra las obras que se ejecutaron durante la intervención. Las obras finalizaron justo para la celebración del 50 aniversario de su construcción en 2012.

  15. Proteste in Venezuela und die Krise des Chavismus

    OpenAIRE

    Mijares, Víctor M.

    2014-01-01

    Seit Wochen demonstrieren in Venezuela Gegner der Regierung von Nicolás Maduro gegen Gewaltkriminalität, Inflation und die Einschränkung bürgerlicher Grundrechte. Die Regierung antwortet mit Repression und lässt einen führenden Oppositionspolitiker verhaften. Venezuela steht vor einem neuen Zyklus der Instabilität. Das während der Präsidentschaft von Hugo Chávez (1999-2013) etablierte sozioökonomische Modell stößt schon im ersten Amtsjahr seines Nachfolgers Nicolás Maduro an seine Grenzen: Ve...

  16. Design, Development and Preliminary Student Evaluation of Virtual Field Guides as aids to teaching and learning in the Earth sciences

    Science.gov (United States)

    Stott, Tim

    2010-05-01

    In Universities the benefits of teaching and learning through fieldwork has been brought under closer examination in recent years (e.g. Andrews et al., 2003) and the notion of supporting fieldwork in the Geography, Earth and Environmental Science (GEES) disciplines has been gathering momentum over the past decade as evidenced by conferences on ‘Supporting fieldwork using information technology' (Maskall et al., 2007) and a Higher Education Academy GEES Virtual Fieldwork Conference at University of Worcester (May 2007). Virtual environments and e-learning resources have been shown to help students become active rather than passive learners by appealing to their multi-sensory learning ability with interactive media (Fletcher et al., 2002; 2007). Research on glacial and fluvial processes has been conducted since 2003 by Liverpool John Moores University (LJMU) staff, sometimes in collaboration with other Universities, at field sites in the French Alps, Swiss Alps and Cariboo Mountains in British Columbia. A virtual field guide (VFG) (www.virtualalps.co.uk) has been developed which uses maps, site photos, panorama movies, video clips, a google earth tour, student exercises using hydrological and glacial datasets collected in the field and revision exercises. A preliminary evaluation of this learning resource has been carried out with two groups of LJMU students and an article written (Stott et al. 2009a). The Ingleton Waterfalls VFG (http://www.ljmu.ac.uk/BIE/ingleton/) was developed by LJMU staff to meet the needs of Foundation degree and undergraduate students. A workshop was presented at the Earth Science Teachers Association 2008 Annual Conference at LJMU, and a subsequent article written (Stott et al. 2009b). The final section of this presentation will summarise some staff perspectives and raises some questions and issues concerned with development and accessibility of VFGs in the light of new developments of a ‘semantic web' at LJMU (Carmichael, 2009). Andrews

  17. A mind of her own

    Science.gov (United States)

    Crease, Robert P.

    2008-03-01

    She is unlikely to be someone that many physicists will have heard of. But Alicia Boole Stott (1860-1940) was one of the first people to explore 4D geometrical figures and had a remarkable ability to conceive how such figures are put together, despite being essentially self-educated. Her path to a mathematics career, however, was full of sorrow, indirection and drama.

  18. Closed-form irreducible differential formulations of the Wilson renormalization group

    International Nuclear Information System (INIS)

    Vvedensky, D.D.; Chang, T.S.; Nicoll, J.F.

    1983-01-01

    We present a detailed derivation of the one-particle--irreducible (1PI) differential renormalization-group generators originally developed by Nicoll and Chang and by Chang, Nicoll, and Young. We illustrate the machinery of the irreducible formulation by calculating to order epsilon 2 the characteristic time exponent z for the time-dependent Ginsburg-Landau model in the cases of conserved and nonconserved order parameter. We then calculate both z and eta to order epsilon 2 by applying to the 1PI generator an extension of the operator expansion technique developed by Wegner for the Wilson smooth-cutoff renormalization-group generator

  19. Fungos micorrízicos vesículo-arbusculares em rizosferas de plantas em dunas do Parque Estadual da Ilha do Cardoso, São Paulo, Brasil: (1 Taxonomia Vesicular-arbuscular mycorrhizal fungi from rhizospheres of dunes plants of Parque Estadual da Ilha do Cardoso, São Paulo State, Brazil (1: taxonomy

    Directory of Open Access Journals (Sweden)

    S. F. B Trufem

    1989-01-01

    Full Text Available De março/1988 a março/1989, mensalmente, foram coletadas o total de 450 amostras de solo de rizosferas de plantas de dunas do Parque Estadual da Ilha do Cardoso, Estado de Sáo Paulo, com a finalidade de se verificar a ocorrência de fungos micorrízicos vesículo-arbusculares (MVA. As plantas mais constantemente investigadas foram: Baccharis trimera DC. (Compositae, Blutaparon portulacoides (St. Hü. Mears (Amaranthaceae, Dalbergia hecastaphylla (L. Taub. (Legurninosae, Hydrocotyle bonariensis Lam. (Umbelliferae,Ipomoeapes-caprae (L.Sweet(Convolvulaceae, Polygaid cyparisseas St. Hül & Moq. (Polygalaceae, além de gramíneas, ciperáceas e outras, que foram coletadas mais esporadicamente. O solo foi tratado pela técnica de decantação e peneiramento em via úmida. Foram verificados 14 taxons de fungos MVA: Acaulospora scrobiculata Trappe, Acaulospora tuberculata Janos & Trappe, Cigaspora gigantea (Nicol. & Gerd. Gerd. & Trappe, Glomus fasciculatum (Thaxter Gerd. & Trappe emend. Walker & Koske, Glomus globiferum Koske & Walker, Glomus monosporum Gerd. & Trappe, Sclerocystis sinuosa Gerd. & Bakshi, Scutellospora calospora (Nicol & Gerd Walker & Sanders, Scutellospora coralloidea (Trappe, Gerd. & Ho (Walker & Sanders, Scutellospora gilmorei (Trappe & Gerd. Walker & Sanders, Scutellospora gregaria (Schenck & Nicol. Walker & Sanders, Scutellospora pérsica (Koske & Walker Walker & Sanders, Scutellospora verrucosa Koske & Walker Walker & Sanders e Scutellospora sp. São apresentadas descrições taxonómicas, comentarios e murônimos dos taxons verificados.Monthly, from March/1988 to March/1989 were collected the total of 450 soil samples from rhizospheres of plants from dunes of Parque Estadual da Ilha do Cardoso, São Paulo State, Brazil, to report the occurrence of VANÍ fungus. The investigated plants were: Baccharis trímera DC. (Compositae, Blutaparon portulacoides (St. Hil. Mears (Amaranthaceae, Dalbergia hecastaphylla (L. Taub

  20. Organizing for a Peaceful Crowd: An Example of a Football Match

    Directory of Open Access Journals (Sweden)

    Ingrid Hylander

    2010-03-01

    Full Text Available Crowd violence has interested researchers in social psychology for many years and is an important issue for sports psychology (STOTT, ADANG, LIVINGSTONE & SCHREIBER, 2007; STOTT, HUTCHINSON & DRURY, 2001; RUSSELL, 2004; MUSTONEN, ARMS & RUSSELL, 1996. Riots in crowds have been explained from different theoretical perspectives (HYLANDER, 2008, such as individual differences, de-individuation (PRENTICE-DUNN & ROGERS, 1989, group interaction (DRURY & REICHER, 2000, history (GUTTMAN, 1986, 1998 and cultural perspectives (CRABBE, 2003. In this study, a social psychology model focusing on group interaction, the Aggravation and Mitigation (AM model (GUVÅ & HYLANDER, 2008; GRANSTRÖM, 2008; GRANSTRÖM & ROSANDER, 2008, is used as a means of analysis. This article applies the AM model to a sporting event to identify if and how peacemaking processes can be detected. Furthermore, the intention is to discern and illuminate organizational strategies that maybe linked to peacemaking processes. The main results indicate that when arrangements are based on (a "festival-making," (b arrangements for basic needs and recognizable order and (c the creation of a superordinate identity, then the outcome of mass events may turn out peaceful, which is also in line with the AM model. URN: urn:nbn:de:0114-fqs100283

  1. Initiating a New Research Phase in the Field of International Entrepreneurship

    DEFF Research Database (Denmark)

    Coviello, Nicole; Tanev, Stoyan

    2017-01-01

    In a recent publication, Nicole Coviello (2015) emphasized the need to re-think existing research on international entrepreneurship and, more specifically, research on born-global firms. She pointed out that the main value of a critical review lies in initiating a new research phase focusing on t...... be of relevance for new technology firms aiming at an international or global engagement from their very inception.......In a recent publication, Nicole Coviello (2015) emphasized the need to re-think existing research on international entrepreneurship and, more specifically, research on born-global firms. She pointed out that the main value of a critical review lies in initiating a new research phase focusing...

  2. Power plants at the bottom of the sea; Kraftwerke auf dem Meeresgrund

    Energy Technology Data Exchange (ETDEWEB)

    Wilhelm, Klaus

    2011-07-01

    The depths of the ocean are a hostile environment. In a bid to defy these adverse conditions, many organisms have teamed up to form close relationships called symbioses. Nicole Dubilier and her colleagues at the Max Planck Institute for Marine Microbiology in Bremen keep discovering new symbioses that provide these deep-sea inhabitants with a guaranteed energy supply. (orig.) [German] Die Tiefen der Ozeane sind ein lebensfeindlicher Ort. Um den widrigen Bedingungen zu trotzen, haben sich viele Organismen zu Lebensgemeinschaften zusammengeschlossen. Nicole Dubilier und ihre Mitarbeiter am Max-Planck-Institut fuer marine Mikrobiologie in Bremen entdecken immer wieder neue Symbiosen, mit denen die Tiefseebewohner ihre Energieversorgung sicherstellen.

  3. Marketing Strategy for Merchant Shipbuilders

    Science.gov (United States)

    1995-01-01

    1995 Ship Production Symposium Paper No. 26: Marketing Strategy for Merchant Shipbuilders U.S. DEPARTMENT OF THE NAVY CARDEROCK DIVISION, NAVAL...Production Symposium Paper No. 26: Marketing Strategy for Merchant Shipbuilders 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6... Marketing Strategy for Merchant Shipbuilders Paul W. Stott (V), A&P Appledore international, U.K. ABSTRACT Much has been published over the years about

  4. Nicolás Macario Alonso, Monte adentro

    OpenAIRE

    Castro Roldán, Andrés

    2014-01-01

    Pantalla negra. Se oye el ruido de la noche campesina y la voz de Blanca, acelerada y fuerte, con las eses sibilantes del acento antioqueño : « Mi abuelo Felipe fue arriero me contaba mi mamá. Andaba todas estas montañas y acampaba en la mitad de los caminos, los hijos de él fueron arrieros y los nietos también heredaron. Heriber, mi marido fue arriero también. El le enseñó el oficio a mis hijos : a Alonso y a Nuvier. Pero la arriería se ha ido muriendo y con ella murió mi esposo. Con la fal...

  5. 723-IJBCS-Article-Marie Nicole Chaungneu G.

    African Journals Online (AJOL)

    DR GATSING

    1 déc. 2005 ... 2 Musée Ecologique du Millénaire (Muséum d'histoire naturelle). ... Une telle approche de gestion pourrait être mise en application dans le cadre des concessions forestières, .... des ressources dans les espaces agroforestiers ..... autres PFNL à l'exemple de trois principaux ...... DUNOD: Paris, France.

  6. Clinical and subclinical deficits at 8 years in a geographically defined cohort of low birthweight infants.

    OpenAIRE

    Pharoah, P O; Stevenson, C J; Cooke, R W; Stevenson, R C

    1994-01-01

    OBJECTIVE--To determine the prevalence of subclinical deficits in cognitive and motor function in low birthweight infants. DESIGN--Children of birth weight < or = 2000 g born to mothers resident in Merseyside in 1980-1 assessed using the Wechsler Intelligence Scale for Children (WISC), the Neale analysis of reading ability, and the Stott-Moyes-Henderson test of motor impairment (TOMI). Children attending normal schools assessed with controls matched for age, sex, and class in school. Children...

  7. Population structure, biomass and distribution of Nyctiphanes ...

    African Journals Online (AJOL)

    1991-06-16

    % full (Nicol, James & Pitcher. 1987). Of these stomachs, 50 were examined under a com- pound microscope to determine food composition. Results. Oceanographic features. A representative temperature/depth section taken ...

  8. 76 FR 59416 - Senior Executive Service Performance Review Board

    Science.gov (United States)

    2011-09-26

    ..., William Danelo, Daniel J. Davis, Delia Davis, Robert de Vallance, Brian Dean, Nicole DeVita, Charles Di..., Roberta Stern, Warren Stewart, Sharon Stinnett, Melanie S. Strack, Barbara L. Stroud, Dennie Michael...

  9. Danish Ultras

    DEFF Research Database (Denmark)

    Havelund, Jonas; Joern, Lise; Rasmussen, Kristian

    2012-01-01

    It is well documented that knowledge of supporter culture is crucial when assessing the risk of disorder at football matches and thereby ensuring a balanced approach by police and stewards (Stott & Pearson 2007). Both within Denmark and internationally, there is a weak understanding of risk suppo....... The article aims to create knowledge concerning ultra supporter culture with the purpose of gaining the information necessary for building differentiated and balanced action on the part of the police and security services....

  10. Probing Androgen Receptor Signaling in Circulating Tumor Cells in Prostate Cancer

    Science.gov (United States)

    2017-10-01

    Writing , review, and/or revision of the manuscript: D.T. Miyamoto, R.J. Lee, S.L. Stott, N.H. Bander, C.-L. Wu, L.V. Sequist, M.R. Smith, M. Toner, S...Maheswaran, D.A. Haber Administrative, technical , or material support (i.e., reporting or organizing data, constructing databases): D.T. Miyamoto...The authors thank J. Walsh, F. Floyd, G. Korir, C. Koris, and L. Libby for technical support. In memory of Charles Evans and in recognition of

  11. Comparison of Three Infrared Thermal Detection Systems and Self Report for Mass Fever Screening

    Centers for Disease Control (CDC) Podcasts

    In this podcast, CDC's Dr. Nicole Cohen describes research that examined the usefulness of thermal scanners for detecting fever in large groups of people in public settings, such as hospitals and airports.

  12. 2009 Joint CBRN Conference

    Science.gov (United States)

    2009-06-25

    Inc. 912 CRISTANINI S.p.A 1015 CUBIC Applications, Inc 1201 CUBRC 427 Decon...Surety Laboratories David Mangino, CUBRC Professional Services Nicole Funk, Booz Allen Hamilton Co-Chairman Vince Nardy, Hunter Defense

  13. Vastukarva pai / Mari Laaniste

    Index Scriptorium Estoniae

    Laaniste, Mari, 1977-

    2007-01-01

    Mängufilm "Karusnahk: Diane Arbuse kujutletav portree" ("Fur: An Imaginary Portrait of Diane Arbuse") : stsenarist Erin Cressida Wilson : režissöör Steven Shainberg : nimiosas Nicole Kidman : Ameerika Ühendriigid 2006

  14. Conocimiento, uso y valor cultural de seis presas del jaguar (Panthera onca y su relación con éste, en San Nicolás de los Montes, San Luis Potosí, Mexico Knowledge, use and cultural value of six prey of jaguar (Panthera onca and their relationship with this species in San Nicolás de los Montes, San Luis Potosí, Mexico

    Directory of Open Access Journals (Sweden)

    Dulce M. Ávila-Nájera

    2011-09-01

    . According to villager´s perception, the more abundant species were pecari, coati and armadillo. Wildlife use for food was the most important since 82% of the interviewed people have consumed some species. The highest value of Cultural Importance was for white tailed deer (27.17. Jaguars in the ejido are considered harmful animals since they prey on livestock. Rural people and jaguars benefit from same wildlife species. The present study is the framework to develop future projects focused on managing and conserving natural resources that exist in the ejido San Nicolás de los Montes, San Luis Potosí.

  15. Nonlinear electron-density distribution around point defects in simple metals. I. Formulation

    International Nuclear Information System (INIS)

    Gupta, A.K.; Jena, P.; Singwi, K.S.

    1978-01-01

    Modification, which is exact in the limit of long wavelength, of the nonlinear theory of Sjoelander and Stott of electron distribution around point defects is given. This modification consists in writing a nonlinear integral equations for the Fourier transform γ 12 (q) of the induced charge density surrounding the point defect, which includes a term involving the density derivative of γ 12 (q). A generalization of the Pauli-Feynman coupling-constant-integration method, together with the Kohn-Sham formalism, is used to exactly determine the coefficient of this derivative term in the long-wavelength limit. The theory is then used to calculate electron-density profiles around a vacancy, an eight-atom void, and a point ion. The results are compared with those of (i) a linear theory, (ii) Sjoelander-Stott theory, and (iii) a fully self-consistent calculation based on the density-functional formalism of Kohn and Sham. It is found that in the case of a vacancy, the results of the present theory are in very good agreement with those based on Kohn-Sham formalism, whereas in the case of a singular attractive potential of a proton, the results are quite poor in the vicinity of the proton, but much better for larger distances. A critical discussion of the theory vis a vis the Kohn-Sham formalism is also given. Some applications of the theory are pointed out

  16. Products Claiming to "Cure" Cancer Are a Cruel Deception

    Science.gov (United States)

    ... products claiming to cure cancer on websites or social media platforms, such as Facebook and Instagram. According to Nicole Kornspan, M.P.H., a consumer safety officer at the U.S. Food and Drug ...

  17. Book Review: Greenwood, M. et al. (Eds.. (2015. Determinants of Indigenous Peoples' Health in Canada: Beyond the Social

    Directory of Open Access Journals (Sweden)

    Javier Mignone

    2017-03-01

    Full Text Available This article provides a review of the book Determinants of Indigenous Peoples’ Health in Canada: Beyond the Social edited by Margo Greenwood, Sarah de Leeuw, Nicole Marie Lindsay, and Charlotte Reading.

  18. Genetics Home Reference: spondyloepimetaphyseal dysplasia, Strudwick type

    Science.gov (United States)

    ... White L, Hills N, Nicol M, Evans G, Cole T, Chapman S, Pope FM. A glycine to aspartic ... medicine? What is newborn screening? New Pages Lyme disease Fibromyalgia White-Sutton syndrome All New & Updated Pages ...

  19. Paremad filmid 3 : Moulin Rouge! / Jaanus Noormets

    Index Scriptorium Estoniae

    Noormets, Jaanus

    2006-01-01

    Muusikafilm "Moulin Rouge" : režissöör Baz Luhrmann : peaosades Nicole Kidman, Ewan McGregor : Ameerika Ühendriigid - Austraalia 2001. Lisatud nimekiri "25 paremat muusikali", mille koostas inglise telekanal Channel 4 2003.a.

  20. Genetics Home Reference: hypokalemic periodic paralysis

    Science.gov (United States)

    ... M, Franques J, Bendahhou S, Lory P, Hainque B, Fournier E, Nicole S, Fontaine B. Hypokalemic Periodic Paralysis. 2002 ... related congenital muscular dystrophy Melorheostosis Rhabdoid tumor predisposition syndrome All New & Updated Pages Reviewed : October 2017 Published : ...

  1. Multiple Sclerosis, Personal Stories | NIH MedlinePlus the Magazine

    Science.gov (United States)

    ... of this page please turn Javascript on. Feature: Multiple Sclerosis Personal Stories: Nicole Lemelle, Iris Young, Michael Anthony, ... something quite different for a person living with multiple sclerosis, such as his girlfriend's brother, Chuy. The more ...

  2. Sügav kummardus Virginia Woolfile / Raili Põldsaar

    Index Scriptorium Estoniae

    Põldsaar, Raili, 1973-

    2003-01-01

    Virginia Woolfi teosest "Mrs. Dalloway" ajendatud Michael Cunninghami romaanil "Tunnid" põhinev mängufilm "Tunnid" ("The Hours") : režissöör Stephen Daldry : kesksetes rollides Meryl Streep, Nicole Kidman, Julianne Moore : Suurbritannia 2002

  3. Kogo dostala Virdzhinija Vulf? / Boris Tuch

    Index Scriptorium Estoniae

    Tuch, Boris, 1946-

    2003-01-01

    Virginia Woolfi teosest "Mrs. Dalloway" ajendatud Michael Cunninghami romaanil "Tunnid" põhinev mängufilm "Tunnid" ("The Hours") : režissöör Stephen Daldry : kesksetes rollides Meryl Streep, Nicole Kidman, Julianne Moore : Suurbritannia 2002

  4. Virginia Woolfi tunnid kummitavad edasi / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2003-01-01

    Virginia Woolfi teosest "Mrs. Dalloway" ajendatud Michael Cunninghami romaanil "Tunnid" põhinev mängufilm "Tunnid" ("The Hours") : režissöör Stephen Daldry : kesksetes rollides Meryl Streep, Nicole Kidman, Julianne Moore : Suurbritannia 2002

  5. Clean Hands Count

    Medline Plus

    Full Text Available ... CDC) 97,825 views 5:12 CDC Flu Education Video - Duration: 10:26. Nicole Shelton 213 views ... Infection Control Video - Duration: 20:55. Paramedical Services Education Page 4,735 views 20:55 Hand Washing ...

  6. 75 FR 66116 - Agency Information Collection Activities: Proposed Collection; Comment Request, OMB No. 1660-NEW...

    Science.gov (United States)

    2010-10-27

    ...; Logistics Capability Assessment Tool (LCAT) AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice... FURTHER INFORMATION CONTACT: Nicole Kelsey, Program Analyst, Logistics Management Directorate, Logistics... DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency [Docket ID: FEMA-2010-0061...

  7. 77 FR 25779 - SBA Council on Underserved Communities

    Science.gov (United States)

    2012-05-01

    ... CONTACT: The meeting is open to the public however advance notice of attendance is requested. Anyone... contact Nicole Nelson by May 3rd 2010, by fax or email in order to be placed on the agenda. [[Page 25780

  8. Social and cultural activities

    CERN Multimedia

    GAC, Jardin d'enfants, Clubs, Association du personnel, Interfon

    2006-01-01

    Groupement des anciens du CERN Nursery School : Enrolment 2006-2007. Exhibition The Club of the week : Yachting Club Yoga. Ski. Solar. Artemusa. Rugby. Record. MicroClub. CineClub. Evening Conference : Nicole and Serge Roetheli. Tour du monde. Interfon

  9. Application of foraminifers in ecotoxicology: Retrospect, perspect and prospect

    Digital Repository Service at National Institute of Oceanography (India)

    Nigam, R.; Saraswat, R.; Panchang, R.

    :112-123; 1964a. Bandy, O.; Ingle Jr., J.C.; Resig, J.M. Foraminifera, Los Angeles County outfall area, California. Limnol. Oceanogra. 9:124-137; 1964b. Bandy, O.; Ingle Jr., J.C.; Resig, J.M. Modification of foraminiferal trends, Hyperion Outfall, California.... Micropal. 10:109-113; 1991. Stott, L.D.; Hayden, T.P.; Griffith, J. Benthic foraminifera at the Los Angeles county Whites Point outfall revisited. J. Foram. Res. 26:357-368; 1996. Stouff, V.; Geslin, E.; Debenay, J.-P.; Lesourd, M. Origin...

  10. Estotilandi taassünd / Mart Kuldkepp

    Index Scriptorium Estoniae

    Kuldkepp, Mart

    2008-01-01

    Alternatiivgeograafiast Vladimir Nabokovi romaani "Ada, ehk, Arm" (1969) näitel. 1558. a. Veneetsias ilmunud anonüümsest reisikirjast "Frislanda, Eslanda, Engrouelanda, Estotilanda ja Icaria saarte avastamine kahe Zeno perekonna venna, Messire Nicoló ja Messire Antonio poolt"

  11. Browse Title Index

    African Journals Online (AJOL)

    Items 51 - 100 of 420 ... By Andrew Nicol and Elmin (2010), Abstract PDF ... Vol 55, No 1 (2017), Breast Cancer and HIV: a South African perspective and a .... Vol 52, No 2 (2014), Comparison between preoperative biopsy and post-excision ...

  12. Genetics Home Reference: Schwartz-Jampel syndrome

    Science.gov (United States)

    ... Fontaine B, Koenig J, Hantaï D, Gueguen A, Fournier E, Eymard B, Nicole S. Peripheral nerve hyperexcitability with preterminal nerve and neuromuscular junction remodeling is a hallmark of Schwartz-Jampel syndrome. Neuromuscul Disord. 2013 Dec;23(12):998-1009. ...

  13. African Journal of Reproductive Health - Vol 17, No 4 (2013)

    African Journals Online (AJOL)

    Risk Factors for Premature Births: A Cross-Sectional Analysis of Hospital Records in a Cameroonian Health Facility. Andreas Chiabi, Evelyn M Mah, Nicole Mvondo, Seraphin Nguefack, Lawrence Mbuagbaw, Karen K Kamga, Shiyuan Zhang, Emile Mboudou, Pierre F Tchokoteu, Elie Mbonda ...

  14. Weight Loss & Acute Porphyria

    Science.gov (United States)

    ... Nicole Castelano Gregary Edwards Megan Parrish ~ How the dog I didn't want became the dog I'd always dreamed of Darnisha Davenport Liz ... or through the site for commercial or public purposes. The American Porphyria Foundation (APF) Tax Forms 990 ...

  15. American Porphyria Foundation

    Science.gov (United States)

    ... Nicole Castelano Gregary Edwards Megan Parrish ~ How the dog I didn't want became the dog I'd always dreamed of Darnisha Davenport Liz ... or through the site for commercial or public purposes. The American Porphyria Foundation (APF) Tax Forms 990 ...

  16. Porphyria Treatment Options

    Science.gov (United States)

    ... Nicole Castelano Gregary Edwards Megan Parrish ~ How the dog I didn't want became the dog I'd always dreamed of Darnisha Davenport Liz ... or through the site for commercial or public purposes. The American Porphyria Foundation (APF) Tax Forms 990 ...

  17. African Journal of AIDS Research - Vol 15, No 4 (2016)

    African Journals Online (AJOL)

    The intersection of antiretroviral therapy, peer support programmes, and economic empowerment with HIV stigma among HIV-positive women in West Nile Uganda · EMAIL FULL TEXT EMAIL FULL TEXT DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Nicole Coffey Kellett, Katherine Gnauck.

  18. Commission of the Economic Affairs, the Environment and the Territory. Report no. 12

    International Nuclear Information System (INIS)

    Ollier, P.; Gonnot, F.M.

    2002-11-01

    This report presents the decisions adjudged by the commission concerning the law project no. 306 relative to the energy markets and to the energy public utilities. The opinion of Nicole Fontaine, delegated Minister of the Industry, is revealed. (A.L.B.)

  19. Risk Factors for Premature Births: A Cross-Sectional Analysis of ...

    African Journals Online (AJOL)

    Risk Factors for Premature Births: A Cross-Sectional Analysis of Hospital Records in a Cameroonian Health Facility. Andreas Chiabi, Evelyn M Mah, Nicole Mvondo, Seraphin Nguefack, Lawrence Mbuagbaw, Karen K Kamga, Shiyuan Zhang, Emile Mboudou, Pierre F Tchokoteu, Elie Mbonda ...

  20. African Journal of AIDS Research - Vol 8, No 4 (2009)

    African Journals Online (AJOL)

    Mobilising indigenous resources for anthropologically designed HIV-prevention and behaviour-change interventions in southern Africa · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Edward C Green, Cedza Dlamini, Nicole C D'Errico, Allison Ruark, Zoe Duby.

  1. Les dimensions d’une ombre: résonances intermédiales et collaborations artistiques entre femmes

    Directory of Open Access Journals (Sweden)

    Maryse Larivière

    2014-04-01

    Full Text Available Au sujet de l’ouvrage d’Andrea Oberhuber, Corps de papier : résonances[avec des accompagnements de Catherine Mavrikakis, Nicole Brossard et Verena Stefan] (Québec, QC, Nota Bene, 2012, 237 p. ISBN: 978-2-89518-442-3.

  2. Effects of Chronic Alcohol Exposure on Kainate Receptor-Mediated Neurotransmission in the Hippocampus

    Science.gov (United States)

    2004-09-01

    12917-12922, 1999. Frerking M, and Nicoll RA. Synaptic kainate receptors. Cur Opin Neurobio 10:342-351, 2000. Harvey J and Lacey MG. A postsynaptic...electrophysiological research. Ironically, this preparation was originally developed for use in biochemical studies characterizing energy metabolism in neuronal

  3. Raha varjatud hind / Peter Singer

    Index Scriptorium Estoniae

    Singer, Peter

    2008-01-01

    Kathleen Vohs, Nicole Mead ja Miranda Goode leidsid eksperimentide kaudu viisi, kuidas panna inimesed mõtlema rahast, ilma et neil seda otseselt teha kästaks. Rahast mõtlema suunatud katsealuste grupi käitumine erines suuresti teise grupi käitumisest

  4. A new species of Cinnamomum (Lauraceae) from the Bladen Nature Reserve, southern Belize.

    Science.gov (United States)

    Brewer, Steven W; Stott, Gail L

    2017-01-01

    A new species in the Lauraceae, Cinnamomum bladenense S.W. Brewer & G.L. Stott, is described from the Bladen Nature Reserve in southern Belize. The new species is similar to Cinnamomum brenesii (Standl.) Kosterm., from which it differs by its much smaller, narrowly-campanulate flowers, its inner tepals glabrous abaxially, its shorter petioles, its minutely sericeous younger twigs, and its abaxial leaf surfaces not glaucous and with prominent secondary venation. A description, preliminary conservation assessment, and photographs of the species as well as a key to and notes on the Cinnamomum of Belize are provided.

  5. 77 FR 30310 - Information Collection Activities: Relief or Reduction in Royalty Rates; Proposed Collection...

    Science.gov (United States)

    2012-05-22

    ... independent certified public accountants. Under Sec. 203.81, a report prepared by an independent certified public accountant must accompany the application and post- production report (expansion project, short... instructions to submit public comments and view all related materials. We will post all comments. Email nicole...

  6. Olhando além do campo: o desenvolvimento da agenda de pesquisa da midiatização

    DEFF Research Database (Denmark)

    Hjarvard, Stig; Linares, Nicolás Llano

    2016-01-01

    Interview with Professor Stig Hjarvard, University of Copenhagen, by Nicolás Llano Linares, University of Sao Paulo. For the last decade Stig Hjarvard has been one of the leading proponents of the institutional perspective on mediatization theory. His work regarding both the theoretical framework...

  7. Targeting Androgen Receptor in Breast Cancer: Enzalutamide as a Novel Breast Cancer Therapeutic

    Science.gov (United States)

    2016-09-01

    Publications, Abstracts, and Presentations: Papers: Dawn R. Cochrane, Sebastian Bernales, Britta M. Jacobsen, Diana M. Cittelly, Erin N. Howe, Nicholas C...Dawn R. Cochrane, Sebastian Bernales, Britta M. Jacobsen, Diana M. Cittelly, Erin N. Howe, Nicholas C. D’Amato, Nicole S. Spoelstra, Annie Jean

  8. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. J R Morones-Ibarra1 Ayax Santos-Guevara1. Facultad de Ciencias Físico-Matemáticas, Universidad Autónoma, de Nuevo León, Ciudad Universitaria, San Nicolás de los Garza, Nuevo León, 66450, México ...

  9. African Journal of AIDS Research - Vol 13, No 1 (2014)

    African Journals Online (AJOL)

    Youth mortality due to HIV/AIDS in South Africa, 2001–2009: An analysis of the levels of mortality using life table techniques · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Nicole De Wet, Somefun Oluwaseyi, Clifford Odimegwu ...

  10. (Siegfried), Helena Gunter

    African Journals Online (AJOL)

    Siegfried),. Helena Gunter (Op 'n plaas in Afrika) en verder terug in die tyd: Spoor (Sonja Loots), Kom slag. 'n bees (Izak de Vries) asook werke van Jaco. Botha, Tom Dreyer en andere. In die onlangse verlede was daar ook Maal van Nicole Jaekel ...

  11. 75 FR 22121 - Request for Public Comment on the Scope of Viewpoints Represented on the Industry Trade Advisory...

    Science.gov (United States)

    2010-04-27

    ... Presidential delegation of this authority, USTR and Commerce have established and co-chair sixteen ITACs, plus an ITAC Committee of Chairs. The ITACs provide information and advice addressing the concerns of....commerce.gov ). Dated: April 20, 2010. Nicole Y. Lamb-Hale, Assistant Secretary for Manufacturing and...

  12. From Calculus to Number Theory

    Indian Academy of Sciences (India)

    A. Raghuram

    2016-11-04

    Nov 4, 2016 ... diverges to infinity. This means given any number M, however large, we can add sufficiently many terms in the above series to make the sum larger than M. This was first proved by Nicole Oresme (1323-1382), a brilliant. French philosopher of his times.

  13. Eesti rahvusvärvid homokunsti näitusel

    Index Scriptorium Estoniae

    1998-01-01

    Amsterdami moodsa ja kaasaegse kunsti muuseum Stedelijk näitab 23. augustini homokunsti analüüsivat teemanäitust "From the Corner of the Eye". New Yorgi kunstnik Nicole Eisenman on oma töös kasutanud väikseid Eesti jt. väikeriikide lippe

  14. 1761-IJBCS-Article-Cathérine Nicole Doume Doume

    African Journals Online (AJOL)

    hp

    11-76. Oyekanmi, Funmilayo B. 2011. Bio-ecology of freshwater prawns Macrobrachium vollenhovenii (Herklots, 1857) and. Caridina africana (Kingsley, 1882) at. Asejire Lake and Erin-ijesa waterfalls,. Nigeria. M.Tech. Fisheries Management. Sipauba -Tavares LH. 1998. Limnologia dos Sistemas de Cultivo. Carcinicultura.

  15. International Journal of Health Research

    African Journals Online (AJOL)

    Erah

    2008-06-07

    Jun 7, 2008 ... Press, Boca Raton, USA, 1983; 125-148. 10. Atwood JL, Davis JED, MacNicol DD. Inclusion. Compounds, Vol III. Academic Press, London,. 1984; 333-375. 11. Linares MS, de Bertorello MM, Longhi MR. Effect of hydroxypropyl-β-cyclodextrin on the solubility of an antibacterial Isoxazolyl-naphthoquinone.

  16. Plaadid / Priit Juurmann

    Index Scriptorium Estoniae

    Juurmann, Priit

    2005-01-01

    Uutest heliplaatidest Nicole Willis and The Soul Investigators "Keep Reachin' Up", Pricess Superstar "My Machine", The Darkness "One Way Ticket To Hell...And Back", System Of A Down "Hypnotize", Röövel Ööbik "Supersymmetry", Fort Minor "The Rising Tied", Korn "See You On The Other Side"

  17. Mass shift of σ-meson in nuclear matter

    Indian Academy of Sciences (India)

    Guevara2 Felipe Robledo Padilla1. Facultad de Ciencias Físico-Matemáticas, Universidad Autónoma de Nuevo León, UANL, Av. Universidad S/N Ciudad Universitaria, San Nicolás de los Garza, Nuevo León, C.P. 66451, México; Facultad de ...

  18. 77 FR 63416 - Senior Executive Service; Departmental Offices Performance Review Board Members

    Science.gov (United States)

    2012-10-16

    ... Secretary for Human Resources and Chief Human Capital Officer Bynum, Nicole, Chief of Management Operations... CONTACT: Mario R. Minor, Senior Human Resources Specialist, 1500 Pennsylvania Avenue NW., ATTN: Room 6W529... career appointee, more than half the members shall consist of career appointees. The names and titles of...

  19. Hyphal Growth from Spores of the Mycorrhizal Fungus Glomus Caledonius: Effect of Amino Acids

    DEFF Research Database (Denmark)

    Hepper, C.M.; Jakobsen, Iver

    1983-01-01

    Hyphal growth from spores of Glomus caledonius (Nicol. and Gerd.) Trappe and Gerdemann was stimulated by cystine, glycine and lysine at optimum concentrations of 4.6, 556 and 825 mg l−1 respectively. When all three amino acids were supplied together in water agar, five times more growth...

  20. Indian summer monsoon and winter hydrographic variations over past millennia resolved by clay sedimentation

    Digital Repository Service at National Institute of Oceanography (India)

    Chauhan, O.S.; Dayal, A.M.; Basavaiah, N.; Kader, U.S.A.

    the eastern Arabian Sea, Earth planet. Sci. Lett., 177, 209-218, doi:10.1016/S0012-821X(00)00053-4. Sinha, A., K. G. Cannariato, L. D. Stott, H. Cheng, R. L. Edwards, M. G. Yadava, R. Ramesh, and I. B. Singh (2007), A 900-year (600 to 1500 A.D.) record.../1 (# 3904; latitude 08 o 07.9’ N; Longitude 76 o 01.8’ E; water depth 1400 m; Figure 1) has been chosen for the present study, because: (i) it lies in an area receiving orographically enhanced SWM precipitation, (ii) located in advection path of BBW...

  1. Building Curriculum during Block Play

    Science.gov (United States)

    Andrews, Nicole

    2015-01-01

    Blocks are not just for play! In this article, Nicole Andrews describes observing the interactions of three young boys enthusiastically engaged in the kindergarten block center of their classroom, using blocks in a building project that displayed their ability to use critical thinking skills, physics exploration, and the development of language…

  2. Valores poblacionales de hemoglobina y hematocrito en el área rural del municipio de Manizales Caldas 1999

    OpenAIRE

    Giraldo Arias, Clara; Córdoba Quintero, Matha Lucía

    2011-01-01

    Se trata de un estudio descriptivo exploratorio para determinar valores poblacionales de hemoglobina y hematocrito del área rural de Manizales, de acuerdo al sexo, edad, condición de salud y clasificación nutricional. Nicolás Pérez Almanza, José Arnoby Chacón, Fabio Antonio Galeano

  3. Acetylcholine, Histamine, and Cognition: Two Sides of the Same Coin

    Science.gov (United States)

    Blandina, Patrizio; Efoudebe, Marcel; Cenni, Gabriele; Mannaioni, Pierfrancesco; Passani, Maria Beatrice

    2004-01-01

    The forebrain cholinergic neurons are localized in the nucleus basalis magnocellularis (NBM), the major source of cholinergic innervation to the neocortex and to the amygdala, and in the medium septum-banda diagonalis complex, which provides cholinergic inputs to the hippocampus (Mesulam et al. 1983; Woolf et al. 1984; Nicoll 1985). Basic and…

  4. Adolescent Literacy and Textbooks: An Annotated Bibliography. Final Report from Carnegie Corporation of New York's Council on Advancing Adolescent Literacy

    Science.gov (United States)

    Kamil, Michael

    2010-01-01

    Textbooks are the primary mediator of learning in academic settings. As students progress from elementary school to middle and high school, the need to read textbooks becomes ever more critical. Reading instruction has not, until recently, even begun to take this reality into account (Kamil, Lane, & Nicolls, 2004). Rather, reading instruction has…

  5. Loan Market Competition and Bank Risk-Taking

    NARCIS (Netherlands)

    Wagner, W.B.

    2007-01-01

    Recent literature (Boyd and De Nicoló, 2005) has argued that competition in the loan market lowers bank risk by reducing the risk-taking incentives of borrowers. We show that the impact of loan market competition on banks is reversed if banks can adjust their loan portfolios. The reason is that when

  6. Guest-responsive structural adaptation of a rationally-designed ...

    Indian Academy of Sciences (India)

    From molecules and crystals to materials NATO ASI. Series (The Netherlands: Kluwer). 3. Desiraju G R 2007 Angew. Chem. Int. Ed. 46 8342. 4. MacNicol D D 1994 In Inclusion compounds (London: Academic Press). 5. Weber E 1996 In Shape and symmetry in the design of new hosts, in Comprehensive Supramolecular ...

  7. Activités culturelles

    CERN Multimedia

    Clubs, AP, Interfon

    2005-01-01

    The Club of the week: The CERN Photo Club Cycling Club Golf Club Ciné-Club : La prophétie des grenouilles Concerts du soir MicroClub Ciné-Club : Together Ciné-Club : Vertigo Evening Conference : Nicole and Serge Roetheli Café des sciences : Les Tribulations d'un jardin en ville Interfon

  8. Design and fabrication of an automated temperature programmed ...

    Indian Academy of Sciences (India)

    Unknown

    Testing of 3-way catalysis with CO, NO and C2H2 to convert to CO2, N2 and H2O is done with this catalyst which .... proper settings on the emission control, mass range, scan rate etc. to ..... Robertson S D, McNicol B D, De Bass J H, Kloet S.

  9. Just like My Nanny: Troubling Teacher's Social Identities in the Classroom

    Science.gov (United States)

    Tan, Edna

    2013-01-01

    Teacher-researcher narrative accounts are essential and insightful for the science education field, yet they are few and far-between. In this forum, I engage in dialogue with Nicole Grimes's auto-ethnographic narrative on the affordances her femme-Caribbean identity allowed for some students to engage more deeply in science. While I agree with and…

  10. My Entirely Plausible Fantasy: Early Mathematics Education in the Age of the Touchscreen Computer

    Science.gov (United States)

    Ginsburg, Herbert P.

    2014-01-01

    This paper offers an account of what early mathematics education could look like in an age of young digital natives. Each "Tubby," as the tablets are called, presents Nicole (our generic little child) with stimulating mathematics microworlds, from which, beginning at age 3, she can learn basic math concepts, as well as methods of…

  11. Learning about the Game: Designing Science Games for a Generation of Gamers

    Science.gov (United States)

    Chmiel, Marjee

    2012-01-01

    This paper is a response to "Challenges and Opportunities: Using a science-based video game in secondary school settings" by Rachel Muehrer, Jennifer Jenson, Jeremy Friedberg, and Nicole Husain. The article highlights two critical areas that I argue require more research in the studies of video games in education. The first area focuses on the…

  12. "Sin azúcar no hay país"

    DEFF Research Database (Denmark)

    Simonsen, Karen-Margrethe

    2014-01-01

    This article investigates the ambiguous image of sugar in the poetry of Nicolás Guillén. It claims that the ambiguity of the sugar-images reflects an ambiguous relation to the past of Cuba and its long history of slavery. Based on the idea of transculturation, as it is conceptualized by Fernando...

  13. Comparison of Three Infrared Thermal Detection Systems and Self Report for Mass Fever Screening

    Centers for Disease Control (CDC) Podcasts

    2010-10-20

    In this podcast, CDC's Dr. Nicole Cohen describes research that examined the usefulness of thermal scanners for detecting fever in large groups of people in public settings, such as hospitals and airports.  Created: 10/20/2010 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 10/20/2010.

  14. Letters tot he Editor: Authors' response | Chowdhury | South African ...

    African Journals Online (AJOL)

    S. Chowdhury, P. Navsaria, S. Edu, A.J Nicol. Abstract. No Abstract. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's ...

  15. Uue jazzi tärkavad tähed. Tulevased jazz-ööd / Siim Nestor

    Index Scriptorium Estoniae

    Nestor, Siim, 1974-

    2005-01-01

    Tänapäeva moodsast jazzist, üritustesarjadest, artistidest ja nende tegevusest. Tänavuse Jazzkaare kontsertidest: Nicole Willis 27. apr. klubis BonBon, Briti soul-funk-ansambel Reel People ja ansambel Hinkus 28. apr. klubis Rock Café, ansambel Cosmoskva 28. apr. Vanalinnastuudio Jazziklubis, norra ansambel Xploding Plastix ja ansambel Kismabande 29. apr. Sakala keskuse suures saalis

  16. Determining Permissible Oxygen and Water Vapor Transmission Rate for Non-Retort Military Ration Packaging

    Science.gov (United States)

    2011-11-01

    OXYGEN AND WATER VAPOR TRANSMISSION RATE FOR NON- RETORT MILITARY RATION PACKAGING by Danielle Froio Alan Wright Nicole Favreau and Sarah...ANSI Std. Z39.18 RETORT STORAGE SHELF LIFE RETORT POUCHES SENSORY ANALYSIS OXYGEN CRACKERS PACKAGING SENSORY... Packaging for MRE. (a) MRE Retort Pouch Quad-Laminate Structure; (b) MRE Non- retort Pouch Tri-Laminate Structure

  17. La costruzione e la decorazione della Sala Maria Luigia nella Biblioteca Palatina di Parma

    Directory of Open Access Journals (Sweden)

    Maria Carla Ramazzini Calciolari

    2011-01-01

    Full Text Available Si ripercorre la storia di una commissione pubblica, la nuova sala della Biblioteca Palatina di Parma, cercando di ricostruire i rapporti intercorsi tra il Bibliotecario Pezzana, l'architetto di Corte Nicolò Bettoli e il Direttore dell'Accademia di Belle Arti Paolo Toschi, e di individuare i modelli culturali, architettonici ed artistici di riferimento.

  18. 2583-IJBCS-Article-Dibi Balé F Gogbe

    African Journals Online (AJOL)

    hp

    aux agents pathogènes, Acta Botanica. Gallica: Botany Letters, 143 (6) 531-. 538. DOI : 10.1080/12538078.1996. 10515350. Clérivet A, Hadrami IE, Bélanger R, Nicole. M. 2003. Résistance du platane. (Platanus spp-ceratocystis fimbriata f. sp platani) au chancre coloré : réactions de défense de la plante et perspectives.

  19. Mission Engineering Competencies Technical Report

    Science.gov (United States)

    2018-04-30

    technology has changed history , Apollo lunar program made a staggering contribution to high tech development. Report No. SERC-2018-TR-106...Gregg Vesonder, Stevens Institute of Technology Co-Principal Investigator: Dr. Dinesh Verma, Stevens Institute of Technology Research Team...Stevens Institute of Technology : Dr. Nicole Hutchison, Mr. Sergio Luna, Mr. William Miller, Dr. Hoong Yan See Tao, Dr. Jon

  20. Army Corps of Engineers: Water Resource Authorizations, Appropriations, and Activities

    Science.gov (United States)

    2017-02-27

    eight divisions that are further divided into 38 districts.2 This report provides an overview of the Corps water resource activities , including...rules associated with authorization and appropriation earmarks, individual Members often brought attention to similar activities for congressional...Army Corps of Engineers: Water Resource Authorizations, Appropriations, and Activities Nicole T. Carter Specialist in Natural Resources Policy

  1. "Learning to Dance"

    Science.gov (United States)

    Keller, Nicole

    2013-01-01

    This article describes how the author, Nicole Keller, found that her writing grew richer and more honest as her understanding of movement and her own body evolved through an Introduction to Modern Dance course. For the first time in her life as an aspiring writer, she felt connected to art, literature, and her personal history in ways that…

  2. Indefinite toxic circles: an art series curated by Nicole Shea

    OpenAIRE

    Sabraw, John; Scott, Conohar; Barker, Mandy

    2017-01-01

    Art is at the forefront when it comes to amplifying the discussions surrounding environmental issues. This series by artists John Sabraw, Conohar Scott, and Mandy Barker illuminates the dangers confronting our waters, from leaking pipes to discarded plastics, to the long-term impact of these toxic products on our most delicate and vulnerable ecosystems and sites. Given the recent declarations of climate change and environmental issues to be “fake news,” projects such as these are crucial in r...

  3. Effect of Au/SiO 2 substrate on the structural and optical properties of ...

    Indian Academy of Sciences (India)

    ... Departamento de Investigación en Física de la Universidad de Sonora, Hermosillo, Sonora, C.P. 83000, México; Facultad de Ingeniería Química, Universidad Michoacana de San Nicolás de Hidalgo, Morelia, Michoacán, C.P. 58030, México; Centro de Nanociencias y Nanotecnología, Universidad Nacional Autónoma de ...

  4. Mass shift of σ-meson in nuclear matter

    Indian Academy of Sciences (India)

    Mass shift of σ-meson in nuclear matter. J R MORONES-IBARRA1, MÓNICA MENCHACA MACIEL1,∗. ,. AYAX SANTOS-GUEVARA2 and FELIPE ROBLEDO PADILLA1. 1Facultad de Ciencias Físico-Matemáticas, Universidad Autónoma de Nuevo León, UANL,. Av. Universidad S/N Ciudad Universitaria, San Nicolás de los ...

  5. A Model of Emotion Management for U.S. Army Leaders

    Science.gov (United States)

    2010-12-01

    55-75). Mahwah, NJ: Lawrence Erlbaum Associates. Charbonneau, D., & Nicol, A. (2002). Emotional intelligence and prosocial behaviors in...York: Guilford. Gross, J. J., & John, O. P. (1997) Revealing feelings : Facets of emotional expressivity in self- reports, peer ratings, and behavior ... feelings – meditation may result in people automatically regulating emotions and thus they are not as sensitive to changes in affective situations

  6. Mass shift of σ-meson in nuclear matter

    Indian Academy of Sciences (India)

    Facultad de Ciencias Físico-Matemáticas, Universidad Autónoma de Nuevo León, UANL, Av. Universidad S/N Ciudad Universitaria, San Nicolás de los Garza, Nuevo León, C.P. 66451, México; Facultad de Ingeniería y Arquitectura, Universidad Regiomontana, 15 de Mayo 567, Monterrey, N.L., 64000, México ...

  7. The Third Data Release of the Sloan Digital Sky Survey

    Science.gov (United States)

    2005-03-01

    11,12 Michael R. Blanton,10 John J. Bochanski, Jr.,3 William N. Boroski,2 Howard J. Brewington,4 John W. Briggs ,13 J. Brinkmann,4 Robert J. Brunner,14...Maki Sekiguchi,54 Erin Sheldon,8,9 Kazu Shimasaku,47 Nicole M. Silvestri,3 J. Allyn Smith,34,55 Vernesa Smolčić,56 Stephanie A. Snedden,4 Albert

  8. The Second Data Release of the Sloan Digital Sky Survey

    Science.gov (United States)

    2004-07-01

    Bernardi,11 Michael R. Blanton,10 John J. Bochanski, Jr.,3 William N. Boroski,2 John W. Briggs ,8 J. Brinkmann,5 Robert J. Brunner,12 Tamás Budavári,7...Walter A. Siegmund,49 Nicole M. Silvestri,3 J. Allyn Smith,29, 50 Vernesa Smolčić,48 Stephanie A. Snedden,5 Albert Stebbins,2 Chris Stoughton,2

  9. Spectropolarimetric Inversions of the Ca II 8542 Å Line in an M-class Solar Flare

    Science.gov (United States)

    Kuridze, D.; Henriques, V. M. J.; Mathioudakis, M.; Rouppe van der Voort, L.; de la Cruz Rodríguez, J.; Carlsson, M.

    2018-06-01

    We study the M1.9-class solar flare SOL2015-09-27T10:40 UT using high-resolution full Stokes imaging spectropolarimetry of the Ca II 8542 Å line obtained with the CRISP imaging spectropolarimeter at the Swedish 1-m Solar Telescope. Spectropolarimetric inversions using the non-LTE code NICOLE are used to construct semiempirical models of the flaring atmosphere to investigate the structure and evolution of the flare temperature and magnetic field. A comparison of the temperature stratification in flaring and nonflaring areas reveals strong heating of the flare ribbon during the flare peak. The polarization signals of the ribbon in the chromosphere during the flare maximum become stronger when compared to its surroundings and to pre- and post-flare profiles. Furthermore, a comparison of the response functions to perturbations in the line-of-sight magnetic field and temperature in flaring and nonflaring atmospheres shows that during the flare, the Ca II 8542 Å line is more sensitive to the lower atmosphere where the magnetic field is expected to be stronger. The chromospheric magnetic field was also determined with the weak-field approximation, which led to results similar to those obtained with the NICOLE inversions.

  10. Venezuela: Background and U.S. Relations

    Science.gov (United States)

    2016-08-22

    to enhance access to objective information and peaceful debate on key issues, and to promote citizen participation and democratic leadership . 113 At...April 2013 in which acting President Nicolás Maduro narrowly defeated Henrique Capriles of the opposition Democratic Unity Roundtable (MUD), with the...Maduro’s term, through 2018. Organization of American States (OAS) Secretary General Luis Almagro invoked the Inter-American Democratic Charter on the

  11. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    ... A Sauceda-Carvajal1 P J García-Ramírez1 N Flores-Ramírez2. Centro de Investigación en Micr¸o y Nanotecnología, Universidad Veracruzana, 94292, Boca del Río, Veracruz, México; Faculty of Wood Engineering and Technology, University Michoacana of San Nicolás de Hidalgo, Morelia, Michoacán 58060, México ...

  12. Baudelaire y Rimbaud en colombiano

    Directory of Open Access Journals (Sweden)

    Jorge H. Cadavid

    1995-05-01

    Full Text Available Iluminaciones. (traducción y prólogo de Nicolás Suescún. Arthur Rimbaud. El Áncora Editores, Santafé de Bogotá, 1995, 93 págs. Poesía escogida (traducción y prólogo de Andrés Holguín. Charles Baudelaire. El Áncora Editores, Santafé de Bogotá, 1995, 99 págs.

  13. Using Technology, Clinical Workflow Redesign, and Team Solutions to Achieve the Patient Centered Medical Home

    Science.gov (United States)

    2011-01-01

    Redesign, and Team Solutions to Achieve the Patient Centered Medical Home LTC Nicole Kerkenbush, MHA, MN Army Medical Department, Office of the...TITLE AND SUBTITLE Using Technology, Clinical Workflow Redesign, and Team Solutions to Achieve the Patient Centered Medical Home 5a. CONTRACT...Describe how these tools are being used to implement the Patient Centered Medical Home care model 2 2011 MHS Conference MEDCOM AHLTA Provider Satisfaction

  14. Dominguez-Vigil et al., Afr J Tradit Complement Altern Med. (2015 ...

    African Journals Online (AJOL)

    cadewumi

    1Universidad Autónoma de Nuevo León, Facultad de Ciencias Químicas, Av. Universidad S/N Ciudad Universitaria, San. Nicolás de los Garza, Nuevo León, ..... Subsecretaría de Educación Superior for their financial support through the project: Redes Temáticas de Colaboración Académica. PROMEP/103.5/13/6922.

  15. Editorial team for the CERN Computer News Letter

    CERN Multimedia

    Maximilien Brice

    2004-01-01

    The CERN Computer News Letter (CNL) informs the users of CERN computing facilities about changes and trends in this area. The CNL can also include some conference or meeting reports and technical briefs which can --as they are not necessarily CERN specific-- be helpful to non-CERN users. From left to right: W. von Rueden, Nicole Crémel and François Grey

  16. Eficiência de fungos micorrízicos arbusculares sobre o crescimento do porta-enxerto de pessegueiro 'aldrighi Efficiency of arbuscular mycorrhizal fungi on growth of 'aldrighi' peach tree rootstock

    Directory of Open Access Journals (Sweden)

    José Luis da Silva Nunes

    2009-01-01

    Full Text Available Este trabalho visou avaliar a eficiência de diferentes espécies de fungos micorrízicos arbusculares (FMAs sobre o crescimento vegetativo e o conteúdo de nutrientes de plantas do porta-enxerto de pessegueiro (Prunus persica cv. Aldrighi. O experimento foi realizado no município de Eldorado do Sul (RS, entre 2004 e 2005. Foram utilizados quatro tratamentos de inoculação de estirpes de FMAs (Acaulospora sp. Trappe, Glomus clarum Nicol. & Schenck, Glomus etunicatum Becker & Gerd e Scutellospora heterogama Nicol. & Gerd. e um tratamento testemunha, sem inoculação. O delineamento experimental utilizado foi o de blocos casualizados, com 20 plantas por parcela e quatro repetições. A altura das plantas, o diâmetro do colo, a área foliar, as biomassas fresca e seca, o conteúdo em nutrientes e em substâncias da parte aérea e das raízes e a colonização das raízes foram avaliados aos 180 dias após a semeadura. O uso das espécies de FMAs beneficia o desenvolvimento de plantas do porta-enxerto cv. Aldrighi, e a eficiência da simbiose planta-FMAs é variável com a espécie de FMAs inoculada. As plantas submetidas à inoculação com S. heterogama e G. etunicatum destacaram-se das demais, com maior crescimento vegetativo e maiores teores de nitrogênio, fósforo e potássio nos tecidos.This work aimed to evaluate the eficiency of four species of arbuscular mycorrhizal fungi (AMF on the vegetative growth and the nutrient contents of peach tree rootstocks (Prunus persica cv. Aldrighi. The experiment was conducted at the Estação Experimental Agronômica (EEA of the Universidade Federal do Rio Grande do Sul (UFRGS, Eldorado do Sul, RS, during 2004 and 2005. Four treatments of AMF inoculation strains (Acaulospora sp. Trappe, Glomus clarum Nicol. & Schenck, Glomus etunicatum Becker & Gerd e Scutellospora heterogama Nicol. & Gerd. and one with non-inoculated plants were used. A randomized block design was used, with 20 plants per plot and four

  17. 16 moeõppetundi itaalia stiilis / Nicole Picart, Richard Gianorio, Marie Varvoux

    Index Scriptorium Estoniae

    Picart, Nicole

    2007-01-01

    Itaalia moekunstnikud Gianfranco Ferre, Frida Giannini (Gucci), Graeme Black (Ferragamo), Angela Missioni (Missioni), Laura Lusuardi (Max Mara), Roberto Cavalli, Donatella Versace, Silvia Venturini (Fendi), Gaia Trussardi, Tomas Maier (Bottega Veneta), Dolce & Gabbana, Cristina Ortiz (Brioni), Rossella Jardini (Moschino), Alberta Ferretti, Giorgio Armani, Dean ja Dan Caten (Dsquared 2) iseloomustavad ideaalset naist, itaalia stiili, ajatut moodi ja kommenteerivad oma moekunstnikuks saamist. Lisatud fotod moekunstnikest

  18. Bioeffects on an In Vitro Model by Small-Scale Explosives and Shock Wave Overpressure Impacts

    Science.gov (United States)

    2017-11-01

    Many TBIs are associated with blast from improvised explosive devices.2–4 Explosions are physical, chemical , or nuclear reactions involving a rapid...ARL-TR-8210 ● NOV 2017 US Army Research Laboratory Bioeffects on an In Vitro Model by Small-Scale Explosives and Shock Wave...Research Laboratory Bioeffects on an In Vitro Model by Small-Scale Explosives and Shock Wave Overpressure Impacts by Nicole E Zander, Thuvan

  19. Magnetic dipole moment of the doubly closed-shell plus one proton nucleus $^{49}$Sc

    CERN Multimedia

    Gaulard, C V; Walters, W; Nishimura, K; Muto, S; Bingham, C R

    It is proposed to measure the magnetic moment of $^{49}$Sc by the Nuclear Magnetic Resonance on Oriented Nuclei (NMR-ON) method using the NICOLE on-line nuclear orientation facility. $^{49}$Sc is the neutron rich, doubly closed-shell, nucleus $^{48}$Ca plus one proton. Results will be used to deduce the effective g-factors in the $^{48}$Ca region with reference to nuclear structure and meson exchange current effects.

  20. Multi-species Management Using Modeling and Decision Theory Applications to Integrated Natural Resources Management Planning

    Science.gov (United States)

    2008-06-01

    Engelmann oak and fire (D.M. Lawson); 2) Orcutt’s spineflower (D.M. Lawson); 3) Dead wart -stemmed ceanothus (D.M. Lawson); 4) San Clemente Island sage...sparrow (Nicole Munkwitz) 5) Live wart - stemmed ceanothus (D.M. Lawson) 6) California Least Tern (Steven Eric Smith...41  Figure A1. Generic woody plant model structure. Ovals signify significant life stages and S are survival within and between stages and F

  1. The Roman Empire - The Third Century Crisis and Crisis Management

    Science.gov (United States)

    2012-04-04

    December 2010. Hekster, Olivier, Gerda De Kleijn, and Danielle Slootjes. "Introduction." Impact of Empire. 7, (2006, June 1): 3-10. Koselleck...Crisis of the Third Century. Edited by Olivier Hekster, Gerda De Kleijn, and Danielle Slootjes. Vol. 7, Impact of EMpire. Boston: Brill Academic, 2012...1. Protagoras and John Nicols, Mapping the Crisis of the Third Century, ed. Olivier Hekster, Gerda De Kleijn, and Danielle Slootjes

  2. Nanopharmaceuticals (part 1): products on the market

    OpenAIRE

    Weissig, Volkmar; Pettinger,Tracy; Murdock,Nicole

    2014-01-01

    Volkmar Weissig,1 Tracy K Pettinger,2 Nicole Murdock3 1Department of Pharmaceutical Sciences, Midwestern University College of Pharmacy Glendale, Glendale, AZ, USA; 2Department of Pharmacy Practice and Administrative Sciences, College of Pharmacy, Idaho State University, Pocatello, ID, USA; 3Department of Pharmacy Practice, Midwestern University College of Pharmacy Glendale, Glendale, AZ, USA Abstract: In 2000, the National Institute of Health launched the National Nanotec...

  3. The CI-Flow Project: A System for Total Water Level Prediction from the Summit to the Sea

    Science.gov (United States)

    2011-11-01

    round and may be applied to all types of coastal storms , including intense cool- season extratropical cyclones (i.e., nor’easters). In addition...associated with waves, tides, storm surge, rivers, and rainfall, including interactions at the tidal/surge interface Within this project, Cl-FLOW addresses...presented for Hurricane Isabel (2003), Hurricane Earl (20I0), and Tropical Storm Nicole (2010) for the Tar -Pamlico and Neuse River basins of North

  4. America's black intellectuals: the cultural perspective as the basis of construction of a subjectivity of a liberating's character (1920-1940

    Directory of Open Access Journals (Sweden)

    Pedro Alexander Cubas-Hernández

    2012-12-01

    Full Text Available In this essay, four intellectual experiences based on culture, which had the objective of generating self-esteem in the black population of America, will be analyzed. Marcus Garvey's pan-African ideal, the poetry of the Black movement Harlem Renaissance, the renovating verses of Nicolás Guillén and the incisive journalism of Gustavo Urrutia helped to construct a black subjectivity of liberating nature.---Original in Spanish.

  5. Mindset Matters: Supporting Student Persistence Through The Developmental Mathematics Pipeline

    OpenAIRE

    Kiser, Tracey Nicole

    2016-01-01

    Abstract of the DissertationMindset Matters: Supporting Student Persistence Through The Developmental Mathematics PipelinebyTracey Nicole KiserDoctor of Education in Teaching and LearningUniversity of California, San Diego, 2016Christopher P. Halter, ChairDevelopmental mathematics is one of the most challenging leaks in the mathematics K-20 pipeline. Few students enter two-year colleges prepared to successfully engage in college-level mathematics classes. Many of students who place into devel...

  6. Formation of the U.S. Air Force Aviator Post Traumatic Stress Disorder Study Group

    Science.gov (United States)

    2016-11-15

    Wood, III, John Heaton, Mark Hubner, Nicole Rhodes 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION... Questionnaire -9 PIQ performance intelligence quotient PTSD post-traumatic stress disorder RPA remotely piloted aircraft USAF U.S. Air Force VIQ verbal intelligence quotient ...Human Performance Wing U.S. Air Force School of Aerospace Medicine Aerospace Medicine Department 2510 Fifth St., Bldg. 840 Wright-Patterson AFB, OH

  7. From the Island of the Blue Dolphins: A unique 19th century cache feature from San Nicolas Island, California

    Science.gov (United States)

    Erlandson, Jon M.; Thomas-Barnett, Lisa; Vellanoweth, René L.; Schwartz, Steven J.; Muhs, Daniel R.

    2013-01-01

    A cache feature salvaged from an eroding sea cliff on San Nicolas Island produced two redwood boxes containing more than 200 artifacts of Nicoleño, Native Alaskan, and Euro-American origin. Outside the boxes were four asphaltum-coated baskets, abalone shells, a sandstone dish, and a hafted stone knife. The boxes, made from split redwood planks, contained a variety of artifacts and numerous unmodified bones and teeth from marine mammals, fish, birds, and large land mammals. Nicoleño-style artifacts include 11 knives with redwood handles and stone blades, stone projectile points, steatite ornaments and effigies, a carved stone pipe, abraders and burnishing stones, bird bone whistles, bone and shell pendants, abalone shell dishes, and two unusual barbed shell fishhooks. Artifacts of Native Alaskan style include four bone toggling harpoons, two unilaterally barbed bone harpoon heads, bone harpoon fore-shafts, a ground slate blade, and an adze blade. Objects of Euro-American origin or materials include a brass button, metal harpoon blades, and ten flaked glass bifaces. The contents of the cache feature, dating to the early-to-mid nineteenth century, provide an extraordinary window on a time of European expansion and global economic development that created unique cultural interactions and social transformations.

  8. Crescimento de mudas de maracujazeiro-doce (Passiflora alata Curtis) associadas a fungos micorrízicos arbusculares (Glomeromycota)

    OpenAIRE

    Silva,Maryluce Albuquerque da; Cavalcante,Uided Maaze Tibúrcio; Silva,Fábio Sérgio Barbosa da; Soares,Sueli Aparecida Gomes; Maia,Leonor Costa

    2004-01-01

    Para determinar o efeito de fungos micorrízicos arbusculares sobre o crescimento de mudas de maracujazeiro-doce foi conduzido, em casa de vegetação, experimento com delineamento inteiramente casualizado usando cinco tratamentos de inoculação (200 esporos/planta de Acaulospora longula Spain & Schenck, Gigaspora albida Schenck & Smith, Glomus etunicatum Becker & Gerd., Scutellospora heterogama (Nicol. & Gerd.) Walker & Sanders e controle não inoculado), com sete repetições. ...

  9. Growth and properties of lead iodide thin films by spin coating

    Indian Academy of Sciences (India)

    Facultad de Ingeniería Mecánica y Eléctrica, Universidad Autónoma de Nuevo León, San Nicolás de los Garza, Nuevo León 66455, México; Universidad Autónoma de Nuevo León, Centro de Innovación, Investigación y Desarrollo de Ingeniería y Tecnología, Apodaca, Nuevo León 66600, México; Facultad de Ciencias ...

  10. EL CLIMA ORGANIZACIONAL EN UNA EMPRESA DE CLASE MUNDIAL (CFE ZONA CENTRO OCCIDENTE DE MEXICO)

    OpenAIRE

    Valenzo Jimenez, Marco Alberto; Martinez Arroyo, Jaime Apolinar; Pedraza Rendonrroyo, Oscar Hugo

    2010-01-01

    This present study is a field investigation conducted by the Department of Economic and Administrative Research Technological of Instituto Tecnolуgico de Morelia (ITM) and the Institute of Economic and Business Research (ININNE) belonging to the Universidad Michoacana de San Nicolбs de Hidalgo, designed to determine the organizational environment of the parastatal responsible for the generation, transmission, distribution and marketing of electricity in Mexico, called Comisiуn Federal d...

  11. Implementing first-year assessment principles: An analysis of selected scholarly literature

    OpenAIRE

    Theda Thomas

    2018-01-01

    Assessment plays an important role in students’ learning as students often frame their learning around their assessment tasks. Well-designed assessment can be used to facilitate first-year students making their social and academic transition to university. In 2009, Professor David Nicol prepared a framework for first-year assessment practices that included 12 principles. In this study, these principles were revisited and used to analyse papers from 2013 to 2016 in the journals: ‘Assessment & ...

  12. Update on ranolazine in the management of angina

    OpenAIRE

    Figueredo, Vincent; Codolosa,Jose; Acharjee,Subroto

    2014-01-01

    J Nicolás Codolosa,1 Subroto Acharjee,1 Vincent M Figueredo1,2 1Einstein Center for Heart and Vascular Health, Einstein Medical Center, 2Jefferson Medical College, Philadelphia, PA, USA Abstract: Mortality rates attributable to coronary heart disease have declined in recent years, possibly related to changes in clinical presentation patterns and use of proven secondary prevention strategies. Chronic stable angina (CSA) remains prevalent, and the goal of treatment is control of sym...

  13. Correlation between MRI results and intraoperative findings in patients with silicone breast implants

    OpenAIRE

    Lindenblatt, Nicole; El-Rabadi, Karem; Helbich, Thomas H; Czembirek, Heinrich; Deutinger, Maria; Benditte-Klepetko, Heike

    2014-01-01

    Nicole Lindenblatt,1 Karem El-Rabadi,2 Thomas H Helbich,2 Heinrich Czembirek,3 Maria Deutinger,4 Heike Benditte-Klepetko5 1Division of Plastic and Hand Surgery, Department of Surgery, University Hospital Zurich, Zurich, Switzerland; 2Department of Biomedical Imaging and Image-guided Therapy, Division of Molecular and Gender Imaging, Medical University of Vienna - General Hospital Vienna, 3Department of Radiology, Hospital Wiener Privatklinik, 4Department of Plastic and Reconstructive Surgery,...

  14. Magnetic dipole moments of High-K isomeric states in Hf isotopes

    CERN Multimedia

    Walters, W; Nishimura, K; Bingham, C R

    2007-01-01

    It is proposed to make precision measurements of the magnetic moments of 5 multi-quasi-particle K-isomers in Hf nuclei by the Nuclear Magnetic Resonance of Oriented Nuclei (NMR/ON) technique using the NICOLE on-line nuclear orientation facility and exploiting the unique HfF$_{3}$ beams recently available at ISOLDE. Results will be used to extract single-particle and collective g-factors of the isomeric states and their excitations and to shed new light on their structure.

  15. Interaction of Jet Fuel Hydrocarbon Components with Red Blood Cells and Hemoglobin

    Science.gov (United States)

    2014-06-24

    Directorate (RHDJ), Wright-Patterson AFB, OH. The authors would like to thank Maj. Paul Eden, Nicole Schaeublin, Christin Grabinski, Dr. Jeff Gearhart...We would also like to thank LtCol. Norman Fox (Laboratory Flight Commander), Mrs. Nersa Loh (Supervisor, Transfusion Services), and Mr. Dan Fischer ...Approximately 7.8 mg of hemoglobin sample was concentrated into a total volume of 5 mL of Fischer PBS pH 7.5 buffer using an Amicon Centrifugal Filter Unit

  16. Iberia : capital federal de la IIª República Española (Un proyecto de Rubio i Tuduri

    Directory of Open Access Journals (Sweden)

    Carlos Sambricio

    1996-01-01

    Full Text Available A los pocos meses de proclamarse, en 1931, la II República Española, Nicolás Rubio i Tuduri presentaba —en el marco de la Exposición organizada por la Asociación de Arquitectos de Cataluña, celebrada en la barcelonesa Galería Maragall— una propuesta un tanto sorprendente: el proyecto de una nueva Capital Federal de la República Española que él denominaba Iberia.

  17. Metabolic profiling of plasma amino acids shows that histidine increases following the consumption of pork

    OpenAIRE

    Samman S; Crossett B; Somers M; Bell KJ; Lai NT; Sullivan DR; Petocz P

    2014-01-01

    Samir Samman,1 Ben Crossett,2 Miles Somers,1 Kirstine J Bell,1 Nicole T Lai,1,3 David R Sullivan,3 Peter Petocz4 1Discipline of Nutrition and Metabolism, 2Discipline of Proteomics and Biotechnology, School of Molecular Bioscience, University of Sydney, Sydney, NSW, Australia; 3Department of Clinical Biochemistry, Royal Prince Alfred Hospital, Sydney, NSW, Australia; 4Department of Statistics, Macquarie University, Sydney, NSW, Australia Abstract: Amino acid (AA) status is determined by facto...

  18. Growth of seedlings of sweet-passion fruit (Passiflora alata Curtis) associated to arbuscular mycorrhizal fungi (Glomeromycota)

    OpenAIRE

    Silva, Maryluce Albuquerque da; Cavalcante, Uided Maaze Tibúrcio; Silva, Fábio Sérgio Barbosa da; Soares, Sueli Aparecida Gomes; Maia, Leonor Costa

    2004-01-01

    Para determinar o efeito de fungos micorrízicos arbusculares sobre o crescimento de mudas de maracujazeiro-doce foi conduzido, em casa de vegetação, experimento com delineamento inteiramente casualizado usando cinco tratamentos de inoculação (200 esporos/planta de Acaulospora longula Spain & Schenck, Gigaspora albida Schenck & Smith, Glomus etunicatum Becker & Gerd., Scutellospora heterogama (Nicol. & Gerd.) Walker & Sanders e controle não inoculado), com sete repetições. A cada 20 dias foram...

  19. A systematic review and meta-analysis of Harmonic technology compared with conventional techniques in mastectomy and breast-conserving surgery with lymphadenectomy for breast cancer

    OpenAIRE

    Clymer, Jeffrey; Cheng,Hang; Ferko,Nicole; Patel,Leena; Soleas,Ireena M; Cameron,Chris G; Hinoul,Piet

    2016-01-01

    Hang Cheng,1 Jeffrey W Clymer,1 Nicole C Ferko,2 Leena Patel,2 Ireena M Soleas,2 Chris G Cameron,2 Piet Hinoul1 1Ethicon Inc., Cincinnati, OH, USA; 2Cornerstone Research Group, Burlington, ON, Canada Background: Mastectomy and breast-conserving surgery (BCS) are important treatment options for breast cancer patients. A previous meta-analysis demonstrated that the risk of certain complications can be reduced with the Harmonic technology compared with conventional methods in mastectomy. However...

  20. Proceedings of the Frontiers of Retrovirology Conference 2016

    OpenAIRE

    Zurnic, Irena; H?tter, Sylvia; Lehmann, Ute; Stanke, Nicole; Reh, Juliane; Kern, Tobias; Lindel, Fabian; Gerresheim, Gesche; Hamann, Martin; M?llers, Erik; Lesbats, Paul; Cherepanov, Peter; Serrao, Erik; Engelman, Alan; Lindemann, Dirk

    2016-01-01

    Table of contents Oral presentations Session 1: Entry & uncoating O1 Host cell polo-like kinases (PLKs) promote early prototype foamy virus (PFV) replication Irena Zurnic, Sylvia H?tter, Ute Lehmann, Nicole Stanke, Juliane Reh, Tobias Kern, Fabian Lindel, Gesche Gerresheim, Martin Hamann, Erik M?llers, Paul Lesbats, Peter Cherepanov, Erik Serrao, Alan Engelman, Dirk Lindemann O2 A novel entry/uncoating assay reveals the presence of at least two species of viral capsids during synchronized HIV...

  1. Proceedings of the Frontiers of Retrovirology Conference 2016

    OpenAIRE

    Zurnic, Irena; Hütter, Sylvia; Lehmann, Ute; Stanke, Nicole; Reh, Juliane; Kern, Tobias; Lindel, Fabian; Gerresheim, Gesche; Hamann, Martin; Müllers, Erik; Lesbats, Paul; Cherepanov, Peter; Serrao, Erik; Engelman, Alan; Lindemann, Dirk

    2016-01-01

    Table of contents Oral presentations Session 1: Entry & uncoating O1 Host cell polo-like kinases (PLKs) promote early prototype foamy virus (PFV) replication Irena Zurnic, Sylvia Hütter, Ute Lehmann, Nicole Stanke, Juliane Reh, Tobias Kern, Fabian Lindel, Gesche Gerresheim, Martin Hamann, Erik Müllers, Paul Lesbats, Peter Cherepanov, Erik Serrao, Alan Engelman, Dirk Lindemann O2 A novel entry/uncoating assay reveals the presence of at least two species of viral capsids during synchronized HIV...

  2. Analýza komunikace v procesu změny korporátní identity organizace

    OpenAIRE

    Blanková, Barbora

    2013-01-01

    The topic of the thesis is a change of corporate identity of the company and role of communication during this process. There are components of corporate identity and relationship between corporate identity, image and reputation described in the thesis. Furthermore it is dedicated to integrated marketing communication, internal communication and role of communication in change management. The theoretical knowledge is applied on company Nicoll Česká republika, s.r.o. which have been coming thr...

  3. Nutrition support and dietary interventions for patients with lung cancer: current insights

    OpenAIRE

    Kiss, Nicole

    2016-01-01

    Nicole Kiss1,2 1Nutrition and Speech Pathology Department, Peter MacCallum Cancer Centre, East Melbourne, VIC, Australia; 2Department of Cancer Experiences Research, Peter MacCallum Cancer Centre, East Melbourne, VIC, Australia Abstract: Malnutrition and weight loss are prevalent in patients with lung cancer. The impact of malnutrition on patients with cancer, and specifically in patients with lung cancer, has been demonstrated in a large number of studies. Malnutrition has been shown to neg...

  4. Registration and analysis for images couple : application to mammograms

    OpenAIRE

    Boucher, Arnaud

    2014-01-01

    Advisor: Nicole Vincent. Date and location of PhD thesis defense: 10 January 2013, University of Paris Descartes In this thesis, the problem addressed is the development of a computer-aided diagnosis system (CAD) based on conjoint analysis of several images, and therefore on the comparison of these medical images. The particularity of our approach is to look for evolutions or aberrant new tissues in a given set, rather than attempting to characterize, with a strong a priori, the type of ti...

  5. Spatiotemporal variability in archaeal communities of tropical coastal waters

    Digital Repository Service at National Institute of Oceanography (India)

    Singh, S.K.

    properties on SST biases and the South Asian summer monsoon in a coupled GCM. Clim Dyn 39:811–826 Urakawa H, Martens-Habbena W, Stahl DA (2010) High abundance of ammonia-oxidizing archaea in coastal waters, determined using a modified DNA extraction method...- ments suggests that archaea play a major role in the global nitrification process (Francis et al. 2005; Prosser and Nicol 2008; Wuchter et al. 2006). Denaturing gradient gel electrophoresis (DGGE) is among the reliable techniques for microbial...

  6. The rules of the game

    Science.gov (United States)

    Tay, Lee Yong; Lim, Cher Ping

    2012-12-01

    This response to Rachel Muehrer, Jennifer Jenson, Jeremy Friedberg and Nicole Husain's paper, Challenges and opportunities: Using a science- based video game in secondary school settings, explores the issues encountered while a science-based video game is introduced in secondary school settings. It highlights the importance of the context, the availability of technologies, the skilfulness of the teachers and readiness of the students for a more successful use of games in schools. In addition, the definition of student engagement is also further discussed.

  7. Diffusion Maps and Geometric Harmonics for Automatic Target Recognition (ATR). Volume 2. Appendices

    Science.gov (United States)

    2007-11-01

    research sponsored by AFRL/SNAT under agreement number FA8650-05-1-1800 ( BAA 04-03-SNK Amendment 3). The U.S. Government is authorized to reproduce...Kralik JD, Beck PD, Laubach M, Chapin JK, Kim J, Biggs SJ, Srinivasan MA, Nicolelis MA: Real-time prediction of hand trajectory by ensembles of...now AFRL/RYAT) or the U.S. Government." "This material is based on research sponsored by AFRL/SNAT under agreement number FA8650-05-1-1800 ( BAA 04-03

  8. Targeting Tryptophan Catabolism: A Novel Method to Block Triple-Negative Breast Cancer Metastasis

    Science.gov (United States)

    2017-04-01

    Negative Breast Cancer Nicholas C. D’Amato1, Thomas J. Rogers1, Michael A. Gordon1, Lisa I. Greene1, Dawn R. Cochrane1, Nicole S. Spoelstra1, Travis G...cancer progression. Biochim Biophys Acta 2013;1833:3481–98. 10. Kamarajugadda S, Stemboroski L, Cai Q, Simpson NE, Nayak S, Tan M, et al. Glucose...4664. Published OnlineFirst September 11, 2015.Cancer Res Nicholas C. D’Amato, Thomas J. Rogers, Michael A. Gordon, et al. Metastasis in Triple

  9. Fungos micorrízicos arbusculares (Glomales, Zygomycota na Ilha dos Eucaliptos, Represa do Guarapiranga, São Paulo, SP Arbuscular mycorrhizal fungi (Glomales, Zygomycota from "Ilha dos Eucaliptos", Guarapiranga Reservoir, São Paulo, SP, Brazil

    Directory of Open Access Journals (Sweden)

    Simone de Paula Gomes

    1998-01-01

    Full Text Available Com o objetivo de se conhecer a micota de fungos micorrízicos arbusculares (FMA, Glomales, Zygomycota, coletou-se amostras de solo rizosférico de plantas instaladas em três áreas (plantio de eucaliptos, mata e transição entre ambas em três épocas (março/1996, época chuvosa e final de verão; junho/1996, época de inverno; janeiro/1997, início das chuvas e do verão na Ilha dos Eucaliptos (cerca de 323.500m², na Represa do Guarapiranga, São Paulo, SP. O solo foi processado para a separação dos esporos de FMA segundo a técnica do peneiramento e decantação em via úmida, seguindo-se centrifugação em solução de sacarose 50% (V:V. Os esporos isolados foram preparados em lâminas permanentes com resina PVL. Foram constatados 21 táxons de FMA: Acaulospora excávala Ingleby, Walker & Mason, Acaulospora foveata Trappe & Janos, Acaulospora longula Spain & Schenck, Acaulospora mellea Spain & Schenck, Acaulospora morrowiae Spain & Schenck, Acaulospora spinosa Walker & Trappe, Acaulospora sp. 1, Acaulospora sp. 2, Acaulospora sp. 3, Acaulospora sp. 4, Entrophospora colombiana Spain & Schenck, Gigaspora gigantea Nicol. & Gerd., Gigaspora ramisporopfwra Spain, Sieverding & Schenck, Glomus aggregatum (Schenck & Smith Koske, Glomus etunicatum Becker & Gerd., Glomus geosporum (Nicol. & Gerd. Walker, Glomus invennayum Hall, Glomus macrocarpum Tul. & Tui., Glomus multisubstensum Mukerjii, Bhattacharjee & Tewari, Scutellospora aff. biornata Spain, Sieverding & Toro e Scutellospora erythropa Koske & Walker. A aplicação do índice de similaridade de Sõrensen entre populações de FMA nas diferentes áreas e as épocas de coletas mostrou valores de 64 a 90%, sugerindo não haver seleção dos FMA mediada por esses fatores.With the aim of verifying the occurence of arbuscular mycorrhizal fungi AMF, Glomales, Zygomycota, rhizosphere soil samples were collected in three areas (eucaliptus reforestation, forest and intersection and on three

  10. Making sense of the Sense Model: translation priming with Japanese-English bilinguals

    OpenAIRE

    Allen, David; Conklin, Kathy; Van Heuven, Walter J.B.

    2015-01-01

    Many studies have reported that first language (L1) translation primes speed responses to second language (L2) targets, whereas L2 translation primes generally do not speed up responses to L1 targets in lexical decision. According to the Sense Model (Finkbeiner, Forster, Nicol & Nakamura, 2004) this asymmetry is due to the proportion of senses activated by the prime. Because L2 primes activate only a subset of the L1 translations senses, priming is not observed. In this study we test the pred...

  11. Two dimensional gel electrophoresis using narrow pH 3-5.6 immobilised pH gradient strips identifies potential novel disease biomarkers in plasma or serum

    OpenAIRE

    sprotocols

    2015-01-01

    Authors: Bevin Gangadharan & Nicole Zitzmann ### Abstract Two-dimensional gel electrophoresis (2-DE) is a protein separation technique often used to separate plasma or serum proteins in an attempt to identify novel biomarkers. This protocol describes how to run 2-DE gels using narrow pH 3-5.6 immobilised pH gradient strips to separate 2 mg of serum proteins. pH 3-6 ampholytes are used to enhance the solubility of proteins in this pH range before the serum proteins are separated in the...

  12. Antibacterial Activity of Oenothera rosea (L 'Her) Leaf Extracts

    OpenAIRE

    Gomez-Flores, Ricardo; Reyna-Martínez, Raúl; Tamez-Guerra, Patricia; Quintanilla-Licea, Ramiro

    2012-01-01

    Aims: To determine the antibacterial effect of Oenothera rosea against Escherichia coli, Salmonella enteritidis and Vibrio cholerae. Study Design: In vitro antibacterial study. Place and Duration of Study: Universidad Autónoma de Nuevo León, Facultad de Ciencias Biológicas, Departamento de Microbiología e Inmunología and Departamento de Química, San Nicolás de los Garza, NL. México, from June 2010 to June 2011. Methodology: The antibacterial in vitro effect of methanol and aqueous extracts of...

  13. Proposed strategy for improving capulín cultivation in the municipalities of Domingo Arenas, Calpan and San Nicolas de los Ranchos

    OpenAIRE

    Luz María Páez Reyes; Josset Sánchez Olarte; Mariano Velasco Torres; Adrián Argumedo Macías; Jesús Felipe Álvarez Gaxiola

    2013-01-01

    Currently the municipalities of Domingo Arenas, Calpan and San Nicolás de los Ranchos Puebla State, conditions and have a favorable climate for growing capulín, however, not being given adequate management value the crop, This causes the yields are low and its economic importance is unnoticed. The aim of the investigation was "explore how to improve the economic and productive use capulín through the revaluation of the same by the producers, because of the advantages offered by the cultivati...

  14. New Service Status Board

    CERN Multimedia

    2013-01-01

    On Monday 14 October, the Service Status Board for GS and IT will change. The new Status Board will be integrated with the CERN Service Portal and with the CERN Service Catalogue.   As of today, the SSB will display “Service Incidents”, “Planned Interventions” and “Service Changes”. References valid from 14 October: CERN SSB at https://cern.ch/ssb Computing SSB (previously IT SSB) at https://cern.ch/itssb   Nicole Cremel, IT and GS Service Management Support

  15. The SWEET SPOTS study: a real-world interpretation of the 2012 American Diabetes Association Position Statement regarding individualized A1C targets

    OpenAIRE

    Bieszk, Nella; Grabner, Michael; Wei, Wenhui; Bonine, Nicole G; Stephenson, Judith J

    2016-01-01

    Nella Bieszk,1 Michael Grabner,2 Wenhui Wei,1 Nicole G Bonine,2 Judith J Stephenson,2 1Sanofi US, Inc., Bridgewater, NJ, 2HealthCore, Inc., Wilmington, DE, USA Objective: To evaluate awareness of the 2012 American Diabetes Association (ADA) Position Statement among physicians and assess its effects on patient-centered glycated hemoglobin (A1C) goals in the management of type 2 diabetes (T2D). Research design and methods: The Summarizing Real-World Individualized TrEatmEnT GoalS and Potential ...

  16. El ensayo lírico como experiencia estética-hermenéutica (The Lyric Essay as an Aesthetic-Hermeneutical Experience

    Directory of Open Access Journals (Sweden)

    Luis Javier Hernández Carmona

    2017-11-01

    Full Text Available Se plantea la teorización sobre el ensayo lírico y la generación de la experiencia estética-hermenéutica, a partir de la aplicación de la ontosemiótica como perspectiva metodológica. Con ello, se analizan las prácticas discursivo-literarias que contienen la metarreflexión que desde la extratextualidad da respuesta a los planteos metaforizados, dado que la autonomía del texto y los desdoblamientos del sujeto enunciador implican estrategias de análisis centradas en el cuadrante referencial autor-texto-lector-contexto. Se analizan teorías sobre el ensayo según Montaigne, Lukács, Adorno y Nicol, hasta proponer el ensayo como balance entre lo objetivo y lo subjetivo trascendente.  Abstract A theorization is proposed for the lyric essay and the generation of the aesthetic-hermeneutic experience from the application of ontosemiotics as a methodological perspective. A discussion is presented of discursive-literary practices containing meta-reflection which, from extratextuality, responds to metaphorized approaches that for the autonomy of the text and the splits of the enunciating subject require analytical strategies focusing on the referential quadrant author-text-reader-context. Theories on the essay are reviewed, including those of Montaigne, Lukács, Adorno and Nicol, to propose the essay as a balance between the objective and transcendental subjectivity.

  17. Francisco Giralte y el sepulcro del obispo Gutierre de Carvajal

    Directory of Open Access Journals (Sweden)

    Vasallo Toranzo, Luis

    2013-12-01

    Full Text Available The high valuation placed on the tomb of Bishop Gutierre de Carvajal, sculpted by Francisco de Giralte, resulted in a lawsuit for which the most important artists from Toledo, Alcalá and Madrid were called to testify. Their testimonies, made during the crucial moment when Berruguete died and the court arrived at Madrid are very useful for understanding the artistic appreciation of a work. Thus, relevant artists of the period –Pompeyo Leoni, Nicolás Vergara el Viejo, Jácome Trezo or Juan Bautista de Toledo– attested to the perfect technique, the beauty of the carving, the multiplicity of personages represented next to the dead Bishop, and the wish to achieve their portrait likenesses.La alta tasación alcanzada por el sepulcro del obispo Gutierre de Carvajal, obra de Francisco Giralte, motivó un pleito al que fueron llamados los principales artistas de Toledo, Alcalá y Madrid. Sus testimonios, realizados en el crucial momento en que se produjo la muerte de Berruguete y llegó la corte a Madrid, son muy útiles para conocer la estimación artística de una obra, de la que personajes como Pompeyo Leoni, Nicolás de Vergara el Viejo, Jácome Trezo o Juan Bautista de Toledo ponderaron la perfección técnica, la belleza de su talla, la multiplicación de personajes representados junto al finado y la voluntad retratística presente en todos ellos.

  18. Analysis of the indices of thermal comfort for the conditions of the Mexican Republic; Analisis de los indices de confort termico para las condiciones de la republica mexicana

    Energy Technology Data Exchange (ETDEWEB)

    Fuentes Freixanet, Victor; Rodriguez Viqueira, Manuel [Universidad Autonoma Metropolitana - Unidad Azcapotzalco (Mexico)

    2009-07-15

    The objective of this article is to analyze different indices of thermal comfort for the Mexican Republic. Among them the Fanger (PMV and PPD) physiological methods of comfort and the new effective temperature index are included. The standard effective temperature (SET), as well as the adaptive methods of Humphreys and Nicol, Auliciems, De Dear and Brager. A comparative analysis is done of the different indices through thematic maps determined by interpolation, using a climatic data base of 700 cities obtained from the observatories and stations of the National Meteorological Service. This article pretends to establish general criteria of the thermal comfort to later define design strategies for each one of the climatic regions of the Mexican Republic. [Spanish] El objetivo de este articulo es analizar distintos indices de confort termico para la Republica Mexicana. Entre ellos se incluyen los metodos fisiologicos de confort de Fanger (PMV y PPD), el indice de nueva temperatura efectiva. La temperatura efectiva estandar (SET), asi como los metodos adaptativos de Humphreys y Nicol, Auliciems, De Dear y Brager. Se hace un analisis comparativo de los distintos indices a traves de mapas tematicos determinados por interpolacion, usando una base de datos climaticos de 700 ciudades obtenidos de los observatorios y estaciones del Servicio Meteorologico Nacional. Este articulo presenta establecer criterios generales del confort termico para posteriormente definir estrategias de diseno para cada una de las regiones climaticas de la Republica Mexicana.

  19. Pascal e o amor-próprio

    Directory of Open Access Journals (Sweden)

    Jean-Robert Armogathe

    2006-12-01

    Full Text Available Uma abordagem lexográfica do amor próprio nos escritos de Pascal: carta (1651 sobre a morte de seu pai, frag. La 978 e nove ocorrências nos Pensamentos. A partir dos diferentes "amores-próprios" enumerados pela tradição, o amor-próprio natural de Adão, anterior à Queda, que para Tomás de Aquino é indiferente, é identificado por Jansenius como pervertido em concupiscência. Em sua Apologia, Pascal segue a linha jansenista de um modo tão radical que os teólogos de Port-Royal julgaram preciso mitigar seus sentimentos a ponto de contradizê-lo, como fez Nicole, que descreveu o amor-próprio como um substituto hipocrítico do comportamento virtuoso.A lexicological approach of self-love in Pascal’s writings: letter (1651 about his father’s death, frag. La 978 and nine occurrences in the Pensées. From the different "self-loves" enumerated by the tradition, Adam’s natural self-love, before the Fall, which is indifferent for Thomas Aquinas, is identified by Jansenius as perverted into concupiscentia. In his Apology, Pascal follows the Jansenist line, in such a radical way that the Port-Royal theologians found necessary to mitigate his feelings, up to contradict him, like Nicole did, who described self-love as a hypocritical substitute to virtuous behaviour.

  20. Informe científico de investigador: Rendtorff Birrer, Nicolás Maximiliano (2012)

    OpenAIRE

    Rendtorff Birrer, Nicolás Maximiliano

    2012-01-01

    Desarrollo mi trabajo en el Centro de tecnología de recursos Minerales y cerámica (CETMIC) perteneciente a la CIC y al CONICET, en el grupo de materiales cerámicos liderado por el Dr. E Aglietti. Al mismo tiempo coordino las actividades del sub-grupo de materiales cerámicos tradicionales y participo de diversas colaboraciones científicas nacionales e internacionales. En particular con el Advance ceramic processing group, NIMS, Tsukuba Japón, con el grupo de materiales cerámicos del IFLP (CONI...

  1. 76 FR 33643 - Safety Zone; Nicole Cerrito Birthday Fireworks, Detroit River, Detroit, MI

    Science.gov (United States)

    2011-06-09

    ... Environmental Health Risks and Safety Risks. This rule is not an economically significant rule and does not create an environmental risk to health or risk to safety that may disproportionately affect children... the Port or his designated representative. DATES: This rule is effective from 10 p.m. through 11:15 p...

  2. Emotions and Positional Identity in Becoming a Social Justice Science Teacher: Nicole's Story

    Science.gov (United States)

    Rivera Maulucci, Maria S.

    2013-01-01

    Becoming a social justice teacher, for high-poverty urban settings, is fraught with emotional ambivalence related to personal, professional, relational, political, and cultural social justice issues. Prospective teachers must navigate their sense of justice, grapple with issues of educational disparity, engage with theories of critical,…

  3. “ESTUDIO DE CORROSIÓN DE LOS ACEROS DÚPLEX 2205, AISI 1018 Y LA UNIÓN SOLDADA, EN UN DIGESTOR PARA LA FABRICACIÓN DE PAPEL”

    OpenAIRE

    Vázquez Navarro, Brenda Alondra

    2012-01-01

    El presente trabajo, se realizó en el laboratorio del departamento de corrosión, del Instituto de Investigaciones Metalúrgicas, de la Universidad Michoacana de San Nicolás de Hidalgo. Se estudió la corrosión en el digestor de cocción continua modificada, que se ubica en la planta de papel de la Corporación Scribe en la Ciudad de Morelia, Michoacán. El digestor en estudio, está fabricado principalmente de acero al carbono AISI 1018. En la zona media inferior de este equipo, p...

  4. El papel de actores transnacionales a propósito de la situación derechos humanos en Venezuela

    OpenAIRE

    Falah, Natalia

    2015-01-01

    A partir de febrero de 2014, la historia de la República Bolivariana se fracturó. El descontento popular, la protesta social y las marchas pacíficas son reprimidas como consecuencia de un abuso de poder por parte del gobierno del presidente Nicolás Maduro. Las redes de información y comunicación, en los términos de Margaret Keck y Kathryn Sikkink, han jugado un papel fundamental para poner en evidencia las violaciones sistemáticas a los DD.HH., siendo estos el factor principal que vulnera la ...

  5. Liquid Crystals for Nondestructive Evaluation

    Science.gov (United States)

    1978-09-01

    polarizers (e.g., where p is the distance of alignment or pitch, X is the Nicol, Rochon, and Wollaston prisms ) are based upon peak wavelength of scattered...RANGE OF so 45" 45 - EVENT SEVENT T(°C) TEMPERATUJRE TC)4"TEMPERATURE 40RANGE OF T(°) 0-RANGE OF 40LIQUID ’ ൫" CRYSTAL S 36 3S. 30 0 IS 90 180 - I...Temperatures TI > T2 > - > TS defects was possible using the liquid crystal. are the Average TemperatursI Thes Resptivegi. Kapfer , Burns, Salvo, and Doyle

  6. Developing a Mouse Model of Sensory and Cognitive Deficits for Multiple Sclerosis

    Science.gov (United States)

    2013-07-01

    Ozdamar O, Kraus N. Auditory middle latency responses in the guinea pig . Am J Otolaryngol 1983;4(2):116–22. Nicol T, Vernon-Roberts B, Quantock DC... guinea pigs . Hear Res 2010;260(1–2):20–9. van Looij MA, Liem SS, van der Burg H, van der Wees J, De Zeeuw CI, van Zanten BG. Impact of conventional...generate females 5a) Set up 10 breeding pairs of CNP-Cre:FLPeR mice (C57Bl/6J) from our existing colonies Completed. 5b) Mice are born and females

  7. Reaparición

    Directory of Open Access Journals (Sweden)

    Boletín Cultural y Bibliográfico Banco de la República

    1987-04-01

    Full Text Available Con un nuevo formato aparece la publicación universitaria y cultural más antigua de Colombia, la "Revista del Colegio Mayor de Nuestra Señora del Rosario". Con un blanco y negro muy bien usado en 200 páginas, la revista entrega al lector escolios inéditos de Nicolás Gómez Dávila, una cercamiento a la obra de César Vallejo, escrito por Fernando Charry Lara y un ensayo de Víctor Guedez, sobre los fundamentos de la crítica de arte.

  8. Mathematics and God’s Point of View1

    Directory of Open Access Journals (Sweden)

    Król Zbigniew

    2016-03-01

    Full Text Available In this paper the final stages of the historical process of the emergence of actual infinity in mathematics are considered. The application of God’s point of view – i.e. the possibility to create mathematics from a divine perspective, i.e. from the point of view of an eternal, timeless, omniscience and unlimited subject of cognition – is one of the main factors in this process. Nicole Oresme is the first man who systematically used actual infinity in mathematical reasoning, constructions and proofs in geometry.

  9. 1998. Primarias en España. Se inicia la era posfelipista. Almunia versus Borrell. 24 de abril de 1998

    OpenAIRE

    Sanz Díaz, Benito

    2015-01-01

    Primarias en España. Se inicia la era posfelipista. Almunia versus borrell. 24 de abril de 1998. Felipe González: “…no seré candidato a la Secretaría General”. Las elecciones primarias socialistas en el País Vasco. Nicolás Redondo Terreros/Rosa Díez. 14 de marzo de 1998. Almunia opta por las primarias. Almunia versus Borrell. 24 de abril 1998. Borrell se lanza a la piscina. El proceso. Cómo se organizaron las primeras elecciones primarias. La campaña electoral Almunia/Borrell. Sondeos sobre i...

  10. Errores botánicos de Plinio señalados por Leoniceno

    Directory of Open Access Journals (Sweden)

    Valderas, José María

    1990-05-01

    Full Text Available Nicoló Leonicenus, humanist and physician, became the center of a polemic on the errors of Plinius that, at the end, eroded the confidence that still was posed on Plinius until the late XV century. Though Leonicenus claimed that he was guided only by the desire of helping the young physicians in those aspects related lo health and life that were menaced by the historical inertia of the errors, his antagonists tried to bound him to terminological or textual aspects. What those errors are? Which are the methods employed by Leonicenus in revealing them, and on which botanical foundations? Those are the questions that we pretend to solve.

    Nicoló Leoniceno, médico humanista, se convirtió en el centro de una famosa polémica sobre los errores de Plinio, que, a la postre, terminaría por minar la confianza que en el seguíase manteniendo hasta finales del siglo XV. Aunque Leoniceno profesaba que sólo le guiaba ayudar a los médicos jóvenes en aquellas cuestiones pertenecientes a la salud y la vida que se veían amenazadas por la inercia histórica de los errores, sus antagonistas Quisieron confinarle en el terreno terminológico o de traducción textual. Pero, ¿cuáles eran esos errores? ¿Qué métodos emplea en desvelarlos? ¿Cuál es el fundamento botánico? A estas preguntas pretendemos dar respuesta.

  11. La peregrinación autobiográfica de Anastasio-Jerónimo (Gracián de la Madre de Dios

    Directory of Open Access Journals (Sweden)

    Manero Sorolla, M. Pilar

    2001-06-01

    Full Text Available The expulsion in 1592 of the First Provincial of the Discalced Carmelite Order, Jerónimo Gracián de la Madre de Dios (1545-1614, induced him to undertake a pilgrinage to Rome determined to seek the justicie that the new Provincial, Nicolás de Jesús María (Doria and King Philip II had denied him in Spain. The article, beginning with this specific and important event in the course of the Carmelite life and of the Order itself, gives a detailed account of their circumstances and explains Gracian's previous and future peregrination based mainly on his dialogistic autobiography and capital work. La peregrinación de Anastasio: an apology of his innocence and example of his literary value.La expulsión en 1592 del primer provincial del Carmen descalzo, Jerónimo Gracián de la Madre de Dios (1545-1614, condujo a éste a peregrinar a Roma en busca de la justicia que le negaban en España el nuevo provincial, Nicolás de Jesús María (Doria y el rey Felipe II. El artículo, partiendo de este acontecimiento determinante en el rumbo de la existencia del carmelita y de la orden, puntualiza las circunstancias del mismo y selecciona anteriores y sobre todo posteriores peregrinaciones de su existencia, basándose especialmente en su autobiografía dialogada y escrito más importante: La peregrinación de Anastasio, verdadera apología de su inocencia y ejemplo de su valía literaria.

  12. ESTRÉS COMO FACTOR ETIOLÓGICO O PERPETUANTE DE DISFUNCION DE ARTICULACION TEMPORO MANDIBULAR

    OpenAIRE

    López Aguilar, Abigail

    2012-01-01

    El propósito del presente trabajo fué valorar la prevalencia de pacientes con síntomas o signos de disfunción de la articulación Temporo mandibular y si existe relación entre esos síntomas o signos de DTM con el estrés. La muestra seleccionada estuvo integrada por pacientes que reunieron los criterios de selección. Se realizó la Historia clínica de Articulación Temporo Mandibular del Diplomado en prótesis fija, removible y oclusión de la Universidad Michoacana de San Nicolás...

  13. Libertarianism and Positive Rights: Comments on Katz's Reply

    Directory of Open Access Journals (Sweden)

    Nicolás Maloberti

    2009-01-01

    Full Text Available In “Why Libertarians Should Reject Positive Rights,” Joshua Katz offers a critical response to the argument developed by Nicolás Maloberti in “Libertarianism and the Possibility of the Legitimate State.” In this rejoinder, Maloberti argues that Katz’s response fails on two accounts. First, it fails to grasp the nature of the problem his article was ultimately concerned with. Second, it fails to present a solid case for the rejection of the type of positive right that it was argued libertarians should endorse as a solution to that problem.

  14. Apuntes sobre la fotografía en el cine de los HIJOS : Un estudio sobre los films Los Rubios, M y Papá Iván

    OpenAIRE

    Larralde Armas, Florencia

    2012-01-01

    El siguiente artículo propone analizar los diversos usos de imágenes fotográficas en tres films realizados por hijos de desaparecidos por la última dictadura militar argentina; se trata de Los Rubios de Albertina Carri, M de Nicolás Prividera y Papá Iván de María Inés Roqué. Los tres directores trabajan el tema desde su memoria personal, y desde allí tratan de reconstruir el recuerdo de sus padres. Las preguntas por la memoria y qué hacer con su imposibilidad se hacen centrales, y cada uno de...

  15. Composition of the Joint Advisory Appeals Board (JAAB) - 2016 Exercise

    CERN Multimedia

    2016-01-01

                                                Appointed by the Director-General                        Member                                    Nicole POLIVKA / HSE   1st deputy                                 Raymond VENESS / BE   2nd deputy                          ...

  16. Composition of the Joint Advisory Appeals Board (JAAB) - 2015 Exercise

    CERN Multimedia

    HR Department

    2015-01-01

                                                Appointed by the Director-General                        Member                                    Nicole POLIVKA / GS   1st deputy                                 Mats MØLLER / IT   2nd deputy                           ...

  17. Questioni di lessico politico tra traduzioni di testi latini e trasmissione della Politica di Aristotele: libertas e liberté nelle traduzioni di Oresme, Foulechat e del Songe du Vergier

    Directory of Open Access Journals (Sweden)

    Claudio Fiocchi

    2011-10-01

    Full Text Available In order to show the complexity of translating from Latin to French in Middle-Ages, this article focuses on the term libertas. The pivotal question for medieval translators is how to render the different meanings (theological, ethical, political of libertas. Three medieval authors as Denis Foulechat, Evrart de Tremaugon and Nicole Oresme find personal solutions, handling the French of their own age. But are their personal choices consistent with the meaning of the word that they are translating? A creative translator can help his readers and enrich the language they speak, but he can also alter what he is translating.

  18. Crítica de Libros.

    OpenAIRE

    Consuelo Escudero Álvaro; José María Álvarez Martínez; Fernando Colina Pérez; Rafael Serrano García; Mauricio Jalón; G Rubio Valladolid; - Consejo de Redacción

    1994-01-01

    Nicolás CAPARRÓS, Tiempo, temporalidad y Psicoanálisis, Madrid, Quipú, 1994. Consuelo Escudero. lean GARRABÉ, Diccionario taxonómico de psiquiatría, México, Fondo de Cultura Económica, 1993. José María Álvarez Jean GARRABÉ, Histoire de la schizophrénie, París, Seghers, 1992. Fernando Colina Emilio LLEDÓ, Días y libros. Pequeños artículos y otras notas, Valladolid, Junta de Castilla y León, Consejería de Cultura y Turismo, 1994. Rafael Serrano García Jacques LACAN, Le séminaire IV. La relation...

  19. Proverbi italiani nell'Europa del nord

    DEFF Research Database (Denmark)

    Toftgaard, Anders

    2014-01-01

    Castelvetro (1546-1616). Nella Biblioteca Reale di Copenaghen è conservata autografa una raccolta di proverbi da lui composta che costituisce una testimonianza preziosa per indagare come la cultura italiana fu introdotta in Danimarca in questa epoca. Il manoscritto che qui ci interessa specialmente è il GKS...... 2052 4°. Il frontespizio porta il testo seguente: Il Significato | D'Alquanti belli & vari | proverbi dell'Italica Favella, gia fatto | da G. C. M. & hoggi riscritto, & donato,in | segno di perpetua amicitia, all ecc.te | D. di legge, Il S.r Nicolò Crachio | Ambas.re del Ser.mo Re di Dania | a questa...

  20. Desequilibrios demográficos y conflictos internacionales

    OpenAIRE

    Díez Nicolás, Juan

    2014-01-01

    Este texto presenta la conferencia inaugural del Catedrático de Sociología Juand Díez Nicolás en el VII Congreso Andaluz de Sociología.La población ha tenido siempre una gran importancia en la historia de la Humanidad porque, en general, más población ha significado más poder. Esto fue así durante muchos siglos, cuando las sociedades en todo el mundo tenían una tecnología relativamente similar (poco desarrollada).Pero a medida que se produjeron diferencias en el grado de desarrollo t...

  1. Electron-positron correlations in an electron liquid

    International Nuclear Information System (INIS)

    Stachowiak, H.

    1980-01-01

    The importance of studying electron-positron interaction for the interpretation of angular correlation data obtained for metallic systems is emphasized. The most successful approaches to electron-positron correlations in jellium are presented. Those include the Bethe-Goldstone two-body equation proposed by Kahana, the charge-density-dielectric function approach connected with the names of Singwi, Sjolander, Stott and Bhattacharyya and the Sawada boson-generalized Tamm-Dancoff approach elaborated recently by Arponen and Pajanne. In conclusion, it is reported that one can consider that the behaviour of a positron at rest in jellium is relatively well understood, though the problem of the optimal choice of a two-body electron-positron phenomenological equation is still open. Also, the behaviour of a positron in a real metal is not well understood and so far, serious calculations in this field have been performed only on very simple models while realistic calculations of the ACPAQ curves tend to minimize the importance of the problems which remain to be solved. (K.B.)

  2. Francisco de Goya en San Nicolás de los Loreneses de Roma 1770

    Directory of Open Access Journals (Sweden)

    Navarrete Prieto, Benito

    2002-09-01

    Full Text Available La aparición del Cuaderno Italiano de Goya y su posterior estudio por parte de Jesús Urrea, Manuela Mena, Juliet Wilson, Paolo Mangiante, Rogelio Buendía y Arturo Ansón ha venido a desvelar un periodo fascinante en la formación del joven Goya, pudiendo rastrear, no solo los elementos que constituyeron sus fuentes en el periodo de aprendizaje, sino los propios orígenes de su arte y sobre todo constituirse en instrumento para fechar y autentificar obras del artista de su época juvenil entre las que destaca el Aníbal vencedor, felizmente hallado por Urrea y con el que Goya concurrió al premio de la Academia de Parma en 1771....

  3. EL ENSAYO ARGENTINO COMO POLÍTICA CULTURAL Y REMEMORACIÓN CRÍTICA DE LA MODERNIDAD / THE ARGENTINE ESSAY AS CULTURAL POLICY AND CRITICAL REMINISCENCE OF MODERNITY

    Directory of Open Access Journals (Sweden)

    Mariano Yedro

    2016-06-01

    Full Text Available Este texto busca dar cuenta de algunas ideas en torno al ensayo el caso particular de Nicolás Casullo, figura intelectual relevante del ensayismo del medio cultural argentino en las últimas décadas. Particularmente en su método de rememoración, esto es la crítica esbozada contra lógicas neoliberales apelando a saberes de la historia moderna. El texto tiene tres partes: la primera aborda, sucintamente, algunas ideas sobre el ensayo que aparecen en el medio intelectual argentino en el siglo XX. La segunda atiende al género del ensayo en la perspectiva de Casullo. Finalmente, tomando la figura del autor nos centraremos en su crítica al neoliberalismo desde la rememoración de la historia moderna. / This paper explores some ideas about the essay seen as cultural policy of resistance and transformation that in the Argentine intellectual scene operated in the form of criticism towards certain logics unfolded during the years of neoliberalism. We focus on the particular case of Nicolás Casullo, a relevant intellectual figure of essayism in the Argentine cultural scenario in the last decades. Particularly, in his method of reminiscence there is a criticism against neoliberal logics referring to instances of knowledge from modern history. The article is organized into three parts: the first one examines some ideas on the essay in the Argentine intellectual scene in the Twentieth Century. The second one deals with the genre of the essay from the perspective of Casullo. Finally, taking the figure of the author into account we concentrate on his critique towards neoliberalism from the reminiscence of modern history.

  4. DESVÍOS CULTURALES

    Directory of Open Access Journals (Sweden)

    Nicolas Consuegra

    2011-04-01

    Full Text Available En este artículo, Nicolás Consuegra hace un análisis de su proyecto de tesis de maestría en el Pratt Institute de Nueva York. El autor hace referencia a las diversas fuentes que lo llevaron a trabajar con la leyenda de El Dorado, y explora su relación con un contexto foráneo como el norteamericano, que desconoce la complejidad de este tipo de narrativas en el momento de apropiarlas. Posteriormente, Consuegra hace referencia al rechazo manifestado por una institución como el Museo del Oro en Colombia en el momento de pedir asistencia en su proyecto.

  5. Bulletin du CERCOR n° 32

    Directory of Open Access Journals (Sweden)

    CERCOR

    2008-07-01

    Full Text Available In memoriamHélène Morin-Sauvade s’est donné la mort le mercredi 4 juin 2008, et il semblait impossible de publier ce court texte de présentation des travaux du CERCOR sans évoquer brièvement cette personnalité attachante et compétente sur les épaules de laquelle reposaient tant de projets. Elle était arrivée au CERCOR en janvier 2006, pour remplacer Nicole Bouter qui avait veillé pendant vingt-cinq ans au bon fonctionnement du laboratoire. Ses grandes compétences aussi bien en histoire médiév...

  6. El Ejército Republicano del Centro en la Guerra de la Intervención Francesa, 1862-1867

    OpenAIRE

    Calvillo López, Edgardo Guadalupe

    2012-01-01

    Mi curiosidad por el tema de la Guerra de la Intervención Francesa empezó desde mi niñez. Cada 5 de diciembre me llevaron al centro de Acuitzio para escuchar en los actos cívicos los discursos de los oradores que conmemoraban el canje de prisioneros. Los nombres de Benito Juárez, Maximiliano de Habsburgo, Vicente Riva Palacio, Aquiles Bazaine, Nicolás de Régules, Van der Smissen y José María Arteaga los escuché año tras año, lo que provocó el aumento de mi interés por este tema...

  7. Arvustused / Priit Kenkmann

    Index Scriptorium Estoniae

    Kenkmann, Priit

    2007-01-01

    Heliplaatidest: Mayhem "Ordo Ad Chao", Minotauri "II", Loits "Must album", Mithras "Behind The Shadows Lie Madness", Poison The Well "Versions", Conspiracy "Reincarnated", April "Tidelines", Devin Townsend "Ziltoid The Omniscient", Beggars Ball "Fight This Town", Breed "Breed", Black Witchery "Desecration of the Holy Kingdom", Blood Tsunami "Trash Metal", Vintersorg "Solens Rötter", HND "PatuRaamaT", W.A.S.P. "Dominator", Megadeth "United Abominations", Manowar "Gods of War", Dimmu Borgir "In Sorte Diaboli", Despised Icon "The Ills of Modern Man", Trouble "Simple Mind Condition", The Esoteric "Subverter", Orange Goblin "Healing Through Fire", Marduk "Rom 5:12", Nicole "Sivu syyttömistä", Korpiklaani "Tervaskanto", Gaia Epicus "Victory", Lumsk "Det Vilde Kor"

  8. Estructura familiar del niño con síndrome de down

    OpenAIRE

    Parra Méndez, Magdalena de Jesús

    2016-01-01

    El objetivo de esta investigación fue describir la estructura familiar del niño Down antes y después del nacimiento y los cambios en familias que tienen un hijo/a con Síndrome de Down, el estudio tiene un enfoque cualitativo. El estudio se realizó en la Unidad de Educación Especial “Nicolás Vásquez” de Paute, participaron padres, madres y representantes de los estudiantes con Síndrome de Down, de 5 a 11 años de edad, para la recolección de la información se aplicó “La Guía de Entr...

  9. Eduardo L. Holmberg, Dos partidos en lucha. Fantasía científica : Buenos Aires, Corregidor, 2006, introducción y selección de apéndices: Sandra Gasparini, colección Voces y Letras del Plata, 269 páginas

    OpenAIRE

    Fontana, Patricio

    2006-01-01

    Es posible que, guiado por el título y por la fecha de la primera edición de Dos partidos en lucha (1875), un eventual lector sospeche que en esta novela breve se alude a las disputas que un año antes habían enfrentado a mitristas y alsinistas a propósito de la elección del candidato que debía suceder a Sarmiento en la presidencia; un conflicto que derivó en la elección de Nicolás Avellaneda y, a continuación, en el alzamiento de Mitre, reprimido finalmente por tropas leales al gobierno en la...

  10. A revision of the haploporinae nicoll, 1914 (digenea: haploporidae) from mullets (mugilidae): Saccocoelium Looss, 1902.

    Science.gov (United States)

    Blasco-Costa, Isabel; Montero, Francisco E; Gibson, David I; Balbuena, Juan Antonio; Raga, Juan Antonio; Kostadinova, Aneta

    2009-03-01

    Saccocoelium Looss, 1902 is revised and a key to its recognised species is presented. S. obesum Looss, 1902 (type-species) and S. tensum Looss, 1902 are redescribed based on material from Liza spp. (Pisces: Mugilidae) in Spanish Mediterranean and, in the case of the former, Bulgarian Black Sea waters. Two new species, S. cephali n. sp. and S. currani n. sp., are described from Mugil cephalus L. in Spanish Mediterranean waters. S. gohari Ramadan, Saoud, Ashour & Mansour, 1989b is recognised and commented upon. Lecithobotrys helmymohamedi Ramadan, Saoud, Ashour & Mansour, 1989a, S. portsaidensis El-Shahawi, El-Gindy, Imam & Al-Bassel, 1992, S. saoudi El-Shahawi, El-Gindy, Imam & Al-Bassel, 1992, Neosaccocoelium aegyptiacus El-Shahawi, El-Gindy, Imam & Al-Bassel, 1992 are considered to be synonyms of S. tensum and Neosaccocoelium El-Shahawi, El-Gindy, Imam & Al-Bassel, 1992 a synonym of Saccocoelium. S. obesum, S. tensum and the two new species are compared morphometrically and distinguished by univariate and multivariate analyses. Lecithobotrys mugilis Rekharani & Madhavi, 1985 is transferred to Unisaccus Martin, 1973 as U. mugilis (Rekharani & Madhavi, 1985) n. comb., and Lecithobotrys sprenti Martin, 1973 [= Saccocoelium sprenti (Martin, 1973) Overstreet & Curran, 2005] is transferred to Unisaccus as U. sprenti (Martin, 1973) n. comb. S. megasacculum Liu, Wang, Peng, Yu & Yang, 2004 is transferred to Elliptobursa Wu, Lu & Zhu, 1996 as E. megasacculum (Liu, Wang, Peng, Yu & Yang, 2004) n. comb. S. tripathi Dutta, 1995 (syn. Saccocoelium tripathi Datta & Manna, 1998) is considered to be a species inquirenda.

  11. Entre el diálogo y el belicismo: dos actitudes ante el turco desde el Occidente a fines del Medievo

    Directory of Open Access Journals (Sweden)

    Mitre Fernández, Emilio

    2010-12-01

    Full Text Available Four authors of XV central century (Nicholas of Cusa, Juan de Segovia, the humanist Eneas Silvio Piccolomini –pope Pio II– and the Bohemian King George Podiebrad and another of the beginning of Modern Age (Erasmus of Rotterdam show correctly the occidental reaction face to the Ottoman pressure, from the fall of Constantinople (1453 to the Hungarian defeat in Mohacs (1526. They consider two ways to solve the problem: the religious dialogue that leads Turkeys to convert to Christianism and then make legitimate their conquest, for example, the short work of Nicholas of Cusa De pace fidei, and partially the Epistula ad Mahumetem of Pius II, and the foundation of a great alliance of Christian princes: vg. the paneuropean project of George Podiebrad, inspired by the old idea of crusade.

    Cuatro autores del siglo XV central, Nicolás de Cusa, Juan de Segovia, el humanista Eneas Silvio Piccolomini –Papa Pío II– y el rey bohemio Jorge Podiebrad, y otro de principios de la Edad Moderna –Erasmo de Rótterdam– muestran correctamente la reacción occidental frente a la presión del Imperio Otomano, desde la caída de Constantinopla en 1453 a la derrota de Hungría en Mohacs en 1526. Examinan dos formas de resolver el problema: el diálogo interreligioso que busca convertir a los turcos al cristianismo y luego legitimar la conquista, por ejemplo el pequeño libro de Nicolás de Cusa De pace fidei y, en parte, la Epistula ad Mahumetem de Pío II; y la creación de una gran alianza de los príncipes cristianos: vg. el proyecto paneuropeo de Jorge Podiebrad, inspirado en la vieja idea de cruzada.

  12. Citología vaginal no útil, causas y riesgos No-useful vaginal cytology causes and risks

    Directory of Open Access Journals (Sweden)

    Yusimí García Trujillo

    2009-09-01

    Full Text Available Se realizó un estudio observacional descriptivo transversal en una muestra de 79 mujeres seleccionadas por muestreo sistemático en el área de salud del policlínico docente "Emilia de Córdoba", de San Nicolás, durante el año 2007, con el objetivo de analizar el comportamiento de la citología vaginal no útil y los factores que propiciaron su incidencia. Se apreció un elevado número de citologías no útiles, lo que constituyó el 23,1 %, y sus principales motivos están relacionados fundamentalmente con dificultades en la técnica y requisitos necesarios para la toma de la muestra. Predominó el grupo de edad de 40 a 44 años; las relaciones sexuales precoces, con 56 casos de 15 a 19 años, para un 70,9 %; y la edad al primer parto por debajo de los 20 años, así como las infecciones de transmisión sexual (la moniliasis y la trichomoniasis. Estuvieron presentes el hábito de fumar y el uso de anticonceptivos hormonales como cofactores.An observational, descriptive and cross-sectional study was carried out in a cohort of 79 women chosen by systemic sampling in health area of "Emilia de Córdoba" Teaching polyclinic, from San Nicolás de Bari municipality during 2007, to analyze behavior of no-useful vaginal cytology and factors causing its incidence. We noted a high figure of non-useful cytologies accounting for 23,1 % and its main causes are fundamentally related to early sexual intercourses in 56 cases aged from 15 to 19, to 70,9 % and age of first delivery was under 20 years, as well as the sexually transmitted infections (moniliasis and trichomoniasis. Smoking and excessive use of hormonal contraceptives were present as cofactors.

  13. National Amnesia of Victims of Torture

    Directory of Open Access Journals (Sweden)

    Julia Estela Monárrez Fragoso

    2017-05-01

    Full Text Available To release from government’s amnesia the torture suffered by a significant proportion of women and men in Mexico, specifically, one segment of Ciudad Juarez’s population, requires an academic commitment. The time frame I analyzed are the years 2006-2015. I make a nexus between two Chicana/ Latina/Feminist theoreticians Nicole Guidotti- Hernández’s narratives of national amnesia; Lisa Marie Cacho’s people ineligible for personhood, and Achille Mbembes’s necropolitics; and Tzvetan Todorov’s governments’ four techniques to control memory. With this theoretical framework I try to comprehend why some women and men are converted into torturable subjects and their torturers remain unknown to the State.

  14. Acoustics Characterization of the Open Chapel´s St. Nicholas of Tolentino Ancient Monastery at Actopan [Hidalgo], Mexico. An example of regional heritage resignification

    Directory of Open Access Journals (Sweden)

    Eduardo Javier García Alonso

    2014-04-01

    Full Text Available This paper summarizes the study of the acoustic behavior of the opened chapel from the “ex convento de San Nicolás de Tolentino”, located in the municipality of Actopan, state of Hidalgo, in Mexico. Such behavior is explained through the acoustic modeling; how at the time, a higher sound pressure level could be attained to cover a longer distance enabling to transmit the religious message to a multitude of parishioners. A collateral and brief historiographic analysis is made about the main function of the opened chapel, and has been complemented with this acustic analysis allowing us to pose new research horizons for this type of heritage buildings at the region.

  15. Louise Michel, de la déportation à l'aventure

    Directory of Open Access Journals (Sweden)

    Danielle Donet-Vincent

    2011-12-01

    Full Text Available Arsène Houssaye vouait au « néant » les femmes de la Commune, réclamant pour elles, qui n'étaient plus tout à fait des femmes, « le silence et l'oubli ».Les recherches de Nicole Priollaud parmi les publications du temps montrent qu'il n'était pas le seul de cette opinion. Émile Zola, en particulier, ne brille pas par son regard novateur sur le comportement des femmes de Paris, ces « disciples plus ou moins folles des religions sociales ». Il  hausse les épaules à leur évocation, ne voyant en ...

  16. Dos momentos de la medicina colombiana

    Directory of Open Access Journals (Sweden)

    Andrés Soriano Lleras

    1963-06-01

    Full Text Available El doctor Nicolás Osorio publicó en el número 37, serie IV, correspondiente al 15 de mayo de 1876, de la "Revista Médica", una nota titulada "Enfermedad del cabello llamada en el Cauca Piedra", en el cual después de hacer una somera descripción de los caracteres del cabello afectado y de hacer constar que no encontró en los tubérculos de los cabellos afectados ninguno de los géneros puccina, mucor, aspergillio, oidium, acho- rion, microsporo y trichophyton, concluye que la causa de la dolencia es desconocida; que no es enfermedad contagiosa y que hasta ese momento no había sido descrita.

  17. As várias faces de Simone: um encontro com os anseios humanos

    Directory of Open Access Journals (Sweden)

    Bernardes, Saimon

    2006-01-01

    Full Text Available Em 2002, o filme S1m0ne, de Andrew Nicoll, trouxe à tona uma nova discussão. No filme, um diretor de cinema passa a utilizar uma atriz criada pelo computador chamada Simone e que, em pouco tempo, torna- se um mito para as pessoas do mundo inteiro. Na era em que digital, virtual, clonagem e fama tornaram- se assuntos comumente falados, o filme levanta diversas possibilidades para essa discussão. Diante disso, o objetivo deste artigo é realizar uma análise do filme S1m0ne focalizando, principalmente, os aspectos: representação, digital, simulacro, mito e imaginário

  18. Análisis de la sostenibilidad del modelo económico venezolano: chavismo, petróleo y distribución de la renta

    Directory of Open Access Journals (Sweden)

    Hernández-Martínez, D.

    2017-11-01

    Full Text Available This paper analyzes the Venezuelan economic model during the governments of Hugo Chávez and Nicolás Maduro (1999-2016, in order to find out if it is in a circumstantial crisis or in a bankruptcy of unsustainability. To do this, the fundamentals of the Chavista economic model are examined, analyzing the policies and reforms that have tried to reverse the structural problems of the Venezuelan economy. The emphasis on redistribution and social spending measures is the key in the popular legitimacy of successive governments. Then, it is described the importance of oil for the development of such policies, crucial element for the country’s growth and survival of the implanted model.

  19. Territoire et exclusion : des mots de l´Etat-providence et des maux de la société civile

    Directory of Open Access Journals (Sweden)

    Catherine Rhein

    1997-10-01

    Full Text Available Dans ce texte qui répond aux réflexions de Nicole Mathieu publiées dans ce même numéro, sont développés trois points. En premier lieu, il est proposé un bref retour aux origines et au sens ŕ donner ŕ la question de l´exclusion. Puis sont abordés les rapports entre territoire et exclusion en milieu urbain, notamment dans les travaux de l´école de sociologie de Chicago. Enfin plusieurs pistes de recherches sont proposées sur les processus et les facteurs d´intégration/exclusion sociales dans les grandes métropoles.

  20. Contenido

    Directory of Open Access Journals (Sweden)

    Facultad de Medicina Revista

    1942-08-01

    Full Text Available I Impotencia coeundi. Prof. Francisco Gnecco  Mozo II pH, y algunos datos de excreción urinaria azoada en los niños. Dr. Jorge Camacho Gamba. III Accidentes de la arsenoterapia. Dr. Nicolás Restrepo Escobar IV Últimos avances médicos presentados ante la 93ª sesión anual de la Asociación Médica Americana en Atlantic city, Estados Unidos, junio 8 a junio 12 de 1942. Contribuciones latino-americanas. Benjamín Mera V Aislamiento de tres cepas de leishmania. Florentino Rey. Alumno de 5° año VI Editorial VII Noticias médicas VIII Revista de revistas

  1. Repertorio Americano 1974-1982. Edición de OCTUBRE-NOVIEMBRE-DICIEMBRE-1981

    OpenAIRE

    Instituto de Estudios Latinoamericanos, UNA

    1981-01-01

    Manuel Arce, El libro de la patria. Un hito en la evolución poética de Alfonso Chase, 1* Sin autor, Fotografía, 1* Sin autor, La Habana, Cuba, con los poetas Adolfo Martí Fuentes, Luis Suardíaz, Angel Augier y Nicolás Guillén, 3* Sin autor, Repertorio Americano, 4* J. G., Semblanza del maestro Joaquín García Monge, 4* Carlos Enrique Aguirre Gómez, Ars poética y poesía en “la piel de los signos” de Mario Picado, 5* Sin autor, El poeta Mario Picado con el también poeta para Julián Marchena, 5* ...

  2. More library mashups exploring new ways to deliver library data

    CERN Document Server

    2015-01-01

    Nicole Engard follows up her ground-breaking 2009 book Library Mashups with a fresh collection of mashup projects that virtually any library can emulate, customize, and build upon. In More Library Mashups, Engard and 24 creative library professionals describe how they are mashing up free and inexpensive digital tools and techniques to improve library services and meet everyday (and unexpected) challenges. Examples from libraries of all types are designed to help even non-programmers share and add value to digital content, update and enhance library websites and collections, mashup catalog data, connect to the library's automation system, and use emerging tools like Serendip-o-matic, Umlaut, and Libki to engage users, staff, and the community.

  3. Two new species of Maritrema Nicoll, 1907 (Digenea: Microphallidae) from New Zealand: morphological and molecular characterisation

    Czech Academy of Sciences Publication Activity Database

    Presswell, B.; Blasco-Costa, I.; Kostadinova, Aneta

    2014-01-01

    Roč. 133, č. 5 (2014), s. 1641-1656 ISSN 0932-0113 Institutional support: RVO:60077344 Keywords : Maritrema * Microphallidae * taxonomy * phylogeny * New Zealand Subject RIV: EA - Cell Biology Impact factor: 2.098, year: 2014

  4. La comedia de la premodernidad a la posmodernidad: de Nicolás Granada a Javier Daulte

    OpenAIRE

    Sikora, Marina

    2013-01-01

    Desde sus orígenes, la comedia en nuestro país estuvo ligada al acontecer histórico y se manifestó como un género teñido de un fuerte didactismo que ya puede observarse en El hipócrita político (anónimo 1820), la primera comedia de costumbres del Río de la Plata. A partir de entonces, fue frecuente la utilización del género para debatir el contexto histórico imperante. A lo largo del tiempo, el género evolucionó sin perder su carácter didáctico, pasando por las renovaciones impuestas por Greg...

  5. [Illness and death of the violin virtuoso Nicolò Paganini--interpretation based on new hair investigations].

    Science.gov (United States)

    Kijewski, Harald; Beck, Jens; Reus, Ulrich

    2012-01-01

    The violin virtuoso Paganini died at Nice in 1840 after a long, severe illness. It is undisputed that Paganini was treated with mercury for suspected syphilis and lost all his teeth in 1828 because of that treatment. In the comprehensive literature published on this topic, most authors assume that the terminal complaints and his death were caused by tuberculosis. On the other hand, the hypothesis that he may have died from mercury poisoning was rejected, because there was no information available supporting this assumption. The authors performed morphological investigations using light microscopy and raster electron microscopy (REM). The examined hairs corresponded to a growth phase of > 1 year and < 3 years before death. Structural damage to the hairs indicate heavy metal intoxication in that phase of life; compatible results were supplied by the complex investigations using ICP mass spectrometry and TXRF, which revealed high concentrations of mercury. Using ICP-MS, the mean value for mercury found in the hair sample was 15.4 microg/g with a standard deviation of 0.7 microg/g. The values obtained when investigating segments of single hairs showed high dispersion, but overlapped with the values from the area investigated using ICP-MS. Information not yet considered in the literature support the diagnosis of syphilis and provide a complete and unambiguous explanation for Paganini's death on the basis of the mercury concentrations found.

  6. Problemi di traduzione della Politica di AristoteleIl caso della traduzione in francese di Nicole Oresme

    Directory of Open Access Journals (Sweden)

    Claudio Fiocchi

    2008-07-01

    Full Text Available Necessità pratiche e riflessioni teoriche accompagnano il lavoro di Oresme, nella consapevolezza che la traduzione delle grandi opere è uno strumento fondamentale per la grandezza di un popolo.

  7. Crocodilian Nest in a Late Cretaceous Sauropod Hatchery from the Type Lameta Ghat Locality, Jabalpur, India.

    Directory of Open Access Journals (Sweden)

    Rahul Srivastava

    Full Text Available The well-known Late Cretaceous Lameta Ghat locality (Jabalpur, India provides a window of opportunity to study a large stable, near shore sandy beach, which was widely used by sauropod dinosaurs as a hatchery. In this paper, we revisit the eggs and eggshell fragments previously assigned to lizards from this locality and reassign them to crocodylomorphs. Several features point to a crocodilian affinity, including a subspherical to ellipsoidal shape, smooth, uneven external surface, discrete trapezoid shaped shell units with wide top and narrow base, basal knobs and wedge shaped crystallites showing typical inverted triangular extinction under crossed nicols. The crocodylomorph eggshell material presented in this paper adds to the skeletal data of these most probably Cretaceous-Eocene dryosaurid crocodiles.

  8. Research ethics and private harms.

    Science.gov (United States)

    Koocher, Gerald P

    2014-12-01

    This commentary addresses the emotionally powerful account of Nicole Taus Kluemper from the perspective of a psychologist familiar with the administrative operation of the American Psychological Association (APA) and the ethics of the profession. The application of the APA's Ethical Principles of Psychologists and Code of Conduct to the case is discussed, and alternative methods of response that researchers who have concerns about case studies might use are offered. The author concludes that existing ethical principles-the aspirational standards in particular-do bear upon the matter in question. However, the enforceable code of conduct is not sufficiently clear about obligations to those whom psychologists publicly discuss when the psychologist does not have a specific duty of care to an individual. © The Author(s) 2014.

  9. Pompas de jabón

    Directory of Open Access Journals (Sweden)

    Jean Michel Vappereau

    2010-12-01

    Full Text Available El presente artículo corresponde al capítulo V del libro: Lu. Le pliage du schéma de Freud, M Bertheux, G-R Saint-Arnaud, N Sottiaux, J-M Vappereau. Topologie En Extension, 1998, Paris. En él se compilan varias conferencias, tanto del Dr. Jean Michel Vappereau como de Michel Bertheux, Guy-Robert Saint-Arnaud y Nicole Sottiaux. La presente traducción fue realizada, bajo la autorización del Dr. Vappereau, por el psicólogo y analista en formación Carlos Andrés Hurtado, y revisada por la psicoanalista argentina María Inés Kaplán. La conferencia fue dictada por el autor en octubre de 1990.

  10. The CERN branch of the UBS has a new manager

    CERN Multimedia

    2005-01-01

    The staff of the UBS CERN branch (apart from Nicole Savoini, not in the picture). The new branch manager Mr Denis Mellet (fourth from the right) is standing just in front of his predecessor Mr Pierre Guyenon. Mr Pierre Guyenon, who has managed the CERN branch of the UBS for the last seven years, retired on 31 May. Pierre Guyenon was always committed to establishing a harmonious and trusting relationship between CERN, its employees and the bank. He also maintained an excellent atmosphere within his team. We would like to thank him for his work and wish him a happy retirement. Mr Denis Mellet, who has worked for the bank for many years in various capacities, has taken over from Mr Guyenon.

  11. Encephalitozoon cuniculi in pet rabbits: diagnosis and optimal management

    Directory of Open Access Journals (Sweden)

    Latney LV

    2014-11-01

    Full Text Available La'Toya V Latney,1 Charles W Bradley,2 Nicole R Wyre1 1Departments of Clinical Studies, 2Departments of Pathobiology, Matthew J Ryan Veterinary Hospital of the University of Pennsylvania, Philadelphia, PA, USA Abstract: Encephalitozoonosis is a significant microsporidial disease of captive pet rabbits (Oryctolagus cuniculus. This article overviews the life cycle, pathogenesis, and host immune response to the parasite. Clinical presentation, differential diagnoses, antemortem diagnostics, and postmortem diagnosis will be discussed. International seroprevalence data and histologic prevalence estimates in the US are presented. A review of current treatment and control recommendations are discussed based on extensive review of controlled studies, which have found fenbendazole to be effective for limiting spread of the disease. Keywords: Encephalitozoon cuniculi, Oryctolagus cuniculi, microsporidia, encephalitozoonosis

  12. The disabling of the EC Disability Regulation: Stott c. Thomas Cook Tour operators Ltd. in the light of the exclusivity Doctrine

    NARCIS (Netherlands)

    Koning, Ingrid

    2014-01-01

    The (contractual) relationship between passengers and airlines is regulated on an international as well as a European level. However, problems arise in the demarcation between these levels. The cause of these demarcation problems lies, on the one hand, in the strict 'exclusivity doctrine' under

  13. Transitioning from military medics to registered nurses

    Directory of Open Access Journals (Sweden)

    Keita MD

    2015-11-01

    Full Text Available Mohamed D Keita,1 Valerie J Diaz,1,2 Audrey P Miller,1 Maria Olenick,1 Sharon R Simon1 1Department of Undergraduate Nursing, Nicole Wertheim College of Nursing and Health Sciences, Florida International University, Miami, 2Operational Health Support Unit Jacksonville, United States Navy Nurse Corps, Jacksonville, FL, USA Abstract: The nursing shortage in the USA is expected to reach 260,000 registered nurses (RNs by 2025. The most profound shortages are expected in California and Florida, translating into 109,779 and 128,364 RN jobs, respectively. Despite a foreseen growth in nursing career opportunities nationwide, the supply of nurses will be insufficient to meet the corresponding demand. Capitalizing on prior education, experience, and skills of military clinical personnel to fill these jobs could significantly reduce the projected nursing shortage. Florida International University's Nicole Wertheim College of Nursing and Health Sciences is circumventing barriers to recruit, retain, and graduate transitioning veteran medics and corpsmen as Bachelor of Science in Nursing prepared RNs who reintegrate into the civilian workforce. The Veteran Bachelor of Science in Nursing (VBSN program is in the form of a cooperative agreement between Florida International University and the US Health Resources and Services Administration. The VBSN program's main objective is to build upon the unique leadership skills, clinical education, and training of military medics and corpsmen to ensure successful completion of the Bachelor of Science in Nursing curriculum. VBSN students, as veterans themselves, have unique knowledge and exposure to the specific health issues and needs of the veteran population overall. They are poised and best prepared to effectively care for the US population, particularly the current 22 million US veterans and 1.6 million Florida veterans. Additionally, the VBSN program will alleviate the challenges, such as the lack of recognition of

  14. An open-label pilot study of pulsed electromagnetic field therapy in the treatment of failed back surgery syndrome pain

    Directory of Open Access Journals (Sweden)

    Harper WL

    2014-12-01

    Full Text Available Wayne L Harper,1 William K Schmidt,2 Nicole J Kubat,3 Richard A Isenberg41Tarheel Clinical Research, LLC, Raleigh, NC, USA; 2NorthStar Consulting, LLC, Davis, CA, USA; 3Nicole Kubat Consulting, Pasadena, CA, USA; 4Regenesis Biomedical, Inc., Scottsdale, AZ, USAAbstract: Persistent pain following back surgery remains a major treatment challenge. The primary objective of this open-label exploratory study was to investigate the analgesic effectiveness of pulsed electromagnetic field therapy administered twice daily over a 45-day period in 34 subjects (68% female with persistent or recurrent pain following back surgery. A secondary goal was to guide the design of future randomized controlled trials that could target responsive subpopulations. All predefined primary and secondary outcomes, including change in pain intensity (PI, physical function (Oswestry Disability Index, analgesic consumption, and overall well-being (Patient Global Impression of Change, are reported. A responder analysis (≥30% reduction in PI versus baseline was added as a post hoc evaluation. Safety outcomes, as well as results of a cost-avoidance survey, are also summarized. Of the 30 per-protocol subjects who completed the study, 33% reported a clinically meaningful (≥30% reduction in PI. A higher response rate (60% was reported for subjects who had undergone discectomy prior to the trial compared to subjects who had undergone other types of surgical interventions (decompression or fusion without discectomy. Improvements in PI were paralleled by improvements in secondary outcomes. Relative to baseline, responders reported an average 44% and 55% reduction in back PI and leg PI (respectively, and an average 13% improvement in Oswestry Disability Index scores. In the per-protocol population, 50% of responders and 12% of nonresponders reported less analgesia consumption at the end of treatment versus baseline. Sixty-seven percent of per-protocol responders and 0% of

  15. Fungos micorrízicos arbusculares em bananeiras cultivadas no Vale do Submédio São Francisco Arbuscular mycorrhizal fungi associated with roots of banana cultivated in the Submédio São Francisco Valley

    Directory of Open Access Journals (Sweden)

    Adriana Mayumi Yano de Melo

    1997-12-01

    Full Text Available Na região do Vale do São Francisco, onde a exploração da agricultura irrigada é a principal responsável pela alta produção de frutas para exportação, a banana é uma das culturas que mais tem se expandido em área cultivada. Com o objetivo de registrar os fungos micorrízicos arbusculares associados a essa cultura, foram coletadas, sob a parte aérea da bananeira, amostras de solo da rizosfera, em quatro áreas com diferentes características de solo, sendo identificadas as espécies: Acaulospora longula Spain & Schenck, A. morrowiae Spain & Schenck, A. rehmii Sieverding & Toro, A. scrobiculata Trappe, A. spinosa Walker & Trappe, A. tuberculata Janos & Trappe, Entrophospora infrequens (Hall Ames & Schneider, Gigaspora ramisporophora Spain, Sieverding & Schenck, Glomus diaphanum Morton & Walker, G. etunicatum Becker & Gerd., G. intraradices Schenck & Smith, G. macrocarpum Tui. & Tui., G. mosseae (Nicol. & Gerd. Gerd. & Trappe, G. occultum Walker e Scutellospora sp. A percentagem de colonização das raízes de bananeiras nas diferentes áreas foi em média 55%.In the region of the São Francisco Valley, where irrigated agriculture is responsable for high production of fruits for exportation, banana is one of the most expanded crops in cultivated areas. In order to know the arbuscular mycorrhizal fungi associated with this crop, samples from the rhizosphere of banana plants were collected in four areas with different soil characteristics, being identified the species: Acaulospora longula Spain & Schenck, A. morrowiae Spain & Schenck, A. rehmii Sieverding & Toro, A. scrobiculata Trappe, A. spinosa Walker & Trappe, A. tuberculata Janos & Trappe, Entrophospora infrequens (Hall Ames & Schneider, Gigaspora ramisporophora Spain, Sieverding & Schenck, Glomus diaphanum Morton & Walker, G. etunicatum Becker & Gerd., G. intraradices Schenck & Smith, G. macrocarpum Tui. & Tui., G. mosseae (Nicol. & Gerd. Gerd. & Trappe, G. occultum Walker and

  16. Suggested guidelines for the management of high-profile fatality cases.

    Science.gov (United States)

    Perper, Joshua A; Juste, Gertrude M; Schueler, Harold E; Motte, Reinhard W; Cina, Stephen J

    2008-10-01

    The investigation of high-profile fatalities poses special challenges to medical examiners and coroners. Most high-profile cases can be readily recognized early in the course of the investigation. Commonly encountered examples include police-related fatalities or deaths in custody, deaths of celebrities, and mass fatalities or clustered deaths (eg, serial killers). Medical examiner and coroner offices should have policies and procedures in place for adequately handling such cases. A rational approach to these high-profile cases includes activating medical examiner or coroner investigative teams, preplanning before the autopsy, using special autopsy techniques and toxicology procedures, skillful questioning of key witnesses, preparing detailed and comprehensive reports, and planning effective communication with the media. The investigation of the sudden and unexpected death of Anna Nicole Smith, an entertainment personality, is presented as an example of how to address the challenging issues inherent in high-profile fatalities and how to adequately prepare for the forensic investigation of high-profile cases. This article presents a methodical approach to the investigation of high-profile deaths. A comprehensive, preplanned forensic investigation and autopsy (including use of adjunctive studies) following the death of Anna Nicole Smith resulted in the accurate determination of the cause and manner of her death while adequately convincing the public of the objectivity and reliability of the Medical Examiners Office with respect to its conclusions. The forensic investigation of death in high-profile cases can be much more tedious and demanding than the investigation of routine cases. It requires more stringent safekeeping of the body and its evidence, more extensive and sophisticated dissection techniques on occasion, and exhaustive toxicologic analysis to exclude low-probability allegations. Procedures for honest, unbiased, and judicious communication with outside

  17. Pharmacological management of binge eating disorder: current and emerging treatment options

    Directory of Open Access Journals (Sweden)

    McElroy SL

    2012-05-01

    Full Text Available Susan L McElroy, Anna I Guerdjikova, Nicole Mori, Anne M O'MeliaLindner Center of HOPE, Mason, and Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH, USAAbstract: Growing evidence suggests that pharmacotherapy may be beneficial for some patients with binge eating disorder (BED, an eating disorder characterized by repetitive episodes of uncontrollable consumption of abnormally large amounts of food without inappropriate weight loss behaviors. In this paper, we provide a brief overview of BED and review the rationales and data supporting the effectiveness of specific medications or medication classes in treating patients with BED. We conclude by summarizing these data, discussing the role of pharmacotherapy in the BED treatment armamentarium, and suggesting future areas for research.Keywords: binge eating disorder, pharmacotherapy, medication management

  18. El aborto en los países de la Subregión Andina: discursos, políticas y resistencias

    Directory of Open Access Journals (Sweden)

    Cristian A. Venegas Ahumada

    2013-01-01

    Full Text Available El objetivo de la investigación es interpretar el discurso hegemónico (icónicolingüístico de los Fundamentalismos Religiosos de Iglesia Católica y grupos ligados a ella, respecto al aborto, junto a las protestas realizadas por movimientos de ciudadanas y ciudadanos por la defensa de los Derechos Sexuales y Reproductivos de las mujeres en países de la Subregión Andina. La metodología utiliza un análisis de discurso. En conclusión: El discurso y penalización del aborto es ideológico, dominación patriarcal que hace adoptar a las mujeres el aborto inseguro como resistencia paralegal, pudiendo enfermar o morir para obtener la libertad sobre su cuerpo, un derecho reproductivo.

  19. Breast manifestations of systemic diseases

    Directory of Open Access Journals (Sweden)

    Dilaveri CA

    2012-02-01

    Full Text Available Christina A Dilaveri, Maire Brid Mac Bride, Nicole P Sandhu, Lonzetta Neal, Karthik Ghosh, Dietlind L Wahner-RoedlerDivision of General Internal Medicine, Mayo Clinic, Rochester, MN, USAAbstract: Although much emphasis has been placed on the primary presentations of breast cancer, little focus has been placed on how systemic illnesses may affect the breast. In this article, we discuss systemic illnesses that can manifest in the breast. We summarize the clinical features, imaging, histopathology, and treatment recommendations for endocrine, vascular, systemic inflammatory, infectious, and hematologic diseases, as well as for the extramammary malignancies that can present in the breast. Despite the rarity of these manifestations of systemic disease, knowledge of these conditions is critical to the appropriate evaluation and treatment of patients presenting with breast symptoms.Keywords: breast, endocrine, hematologic, infectious, vascular

  20. Libertad de expresión, redes sociales y derecho penal. Estudio del caso Nicolás Castro

    Directory of Open Access Journals (Sweden)

    Juan Carlos Upegui Mejía

    2010-12-01

    Full Text Available El autor propone una lectura de la libertad de expresión en la internet a partir del análisis de un caso: la persecución penal de un usuario de Facebook que participa en un grupo que busca asesinar al hijo del presidente de la República. La tesis, al amparo de la Convención americana de derechos humanos, es que ese tipo de discursos esta prohibido, empero, el régimen de responsabilidad aplicable no puede ser de tipo penal. En busca de los límites al ejercicio de dicha libertad el autor intenta perfilar un marco conceptual desde las prácticas, el tipo de discurso, las subjetividades y los valores de la internet. En la autorregulación o en la composición de tipo civil deben fundarse los límites a la libertad de expresión que la resguarden de la autocensura o de la aplicación de un derecho penal del enemigo.

  1. The processing of Brazilian Portuguese anaphora and the influence of dialectal variation

    Directory of Open Access Journals (Sweden)

    Maria Cláudia Mesquita Lacerda

    2014-09-01

    Full Text Available The objective of this research was to investigate whether different types of recovery [se, Ø, ele(a] may influence the coreferential processing of reflective structures, relating to these, the semantics of the verbal predicate. To verify whether the dialectal variation of the use of anaphora “se” (use, removal, and replacement could influence the processing of these structures, we performed a self-paced reading experiment in Minas Gerais and Paraíba. The results showed a significant effect on the type of retrieval, indicating the possibility of the influence of verb type. It is believed that syntactic constraints of the Binding theory (Chomsky, 1981 were activated in early stages of processing (NICOL; SWINNEY, 1989, however, the interpretability from the verbal semantics and the discursive question related to usage factors (range meant that there was a re-examination by the parser.

  2. La transición demográfica en España

    Directory of Open Access Journals (Sweden)

    ESTRELLA REVENGA ARRANZ

    1980-01-01

    Full Text Available Se someten a discusión la producción de tres teóricos de la transición demográfica: Juan Díez Nicolás (ver SA 26:4/78J5488, Salustiano del Campo (Análisis de la población en España, Barcelona: Ariel, 1972 y Amando de Miguel (Manual de estructura social de España, Madrid: Ariel, 1977. Se describen las fases demográficas fundamentales que cabe trazar en la historia de España, comenzando en 1885, desde la perspectiva de los tres autores. Se resumen los argumentos contradictorios, evidenciando así la "guerra de números" en que los autores aludidos se hallan inmersos. Cada uno de ellos propone una periodización diferente, la cual depende de la especificad de su razonamiento causal.

  3. Deep inelastic phenomena

    International Nuclear Information System (INIS)

    Aubert, J.J.

    1982-01-01

    The experimental situation of the deep inelastic scattering for electrons (muons) is reviewed. A brief history of experimentation highlights Mohr and Nicoll's 1932 experiment on electron-atom scattering and Hofstadter's 1950 experiment on electron-nucleus scattering. The phenomenology of electron-nucleon scattering carried out between 1960 and 1970 is described, with emphasis on the parton model, and scaling. Experiments at SLAC and FNAL since 1974 exhibit scaling violations. Three muon-nucleon scattering experiments at BFP, BCDMA, and EMA, currently producing new results in the high Q 2 domain suggest a rather flat behaviour of the structure function at fixed x as a function of Q 2 . It is seen that the structure measured in DIS can then be projected into a pure hadronic process to predict a cross section. Protonneutron difference, moment analysis, and Drell-Yan pairs are also considered

  4. Competencias docentes en los profesores de medicina de la Universidad Michoacana de San Nicolás de Hidalgo

    OpenAIRE

    Manzo Rodríguez, Lidia; Rivera Michelena, Natacha; Rodríguez Orozco, Alain R

    2006-01-01

    Para la identificación de un grupo de competencias docentes básicas en los profesores que se desempeñan en la licenciatura en medicina en la Facultad de Medicina “Dr. Ignacio Chávez”, objetivo fundamental del presente trabajo, se utilizaron métodos teóricos y empíricos. Se aplicó una encuesta a una muestra seleccionada de docentes y alumnos. Se emplearon procedimientos estadísticos para el análisis de los resultados y se elaboraron tablas. A partir de la identificación de las necesidades de a...

  5. Tear osmolarity and dry eye symptoms in diabetics

    Directory of Open Access Journals (Sweden)

    Fuerst N

    2014-03-01

    Full Text Available Nicole Fuerst,1 Nicole Langelier,1 Mina Massaro-Giordano,1 Maxwell Pistilli,1 Kalliopi Stasi,1 Carrie Burns,2 Serena Cardillo,2 Vatinee Y Bunya1 1Department of Ophthalmology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; 2Division of Endocrinology, Diabetes, and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA Purpose: To assess the relationship between tear osmolarity and dry eye symptoms in patients with diabetes. Patients and methods: Fifty patients with diabetes were enrolled. Demographic information and past medical history were recorded. Symptoms were assessed using the ocular surface disease index (OSDI. Tear osmolarity of each eye was measured with the TearLab® Osmolarity System. Results: The majority of the subjects were female (76%, African American (56%, and/or had a diagnosis of type 2 diabetes (82%. The mean ± standard deviation (SD for age was 54.6±13.4, and maximum tear osmolarity was 304.6±12.7 mOsm/L. Men had higher osmolarity than women (mean ± standard error (SE 311.8±4.0 mOsm/L versus 302.3±1.9 mOsm/L, P=0.02. Age, race, use of artificial tears, years of diabetes, and hemoglobin A1c did not have a statistically significant association with tear osmolarity. Longer duration of diabetes was associated with lower (less severe OSDI scores (r=-0.35, P=0.01. Higher tear osmolarity was associated with lower (less severe OSDI scores (r=-0.29, P=0.04. Conclusion: Approximately half of the diabetic subjects in our study had elevated tear osmolarity, and half of our population also reported symptoms consistent with dry eye disease. However, the two were slightly inversely related in that those with higher osmolarity reported fewer symptoms. Subjects with a longer duration of diabetes also reported fewer dry eye symptoms. Therefore, health care providers should be aware that patients who are most likely to have ocular surface disease, including those with

  6. Insights into particle cycling in the Sargasso Sea from lipid biomarkers in suspended particles: Seasonality and physical forcing

    Science.gov (United States)

    Pedrosa Pàmies, R.; Conte, M. H.; Weber, J.

    2017-12-01

    Lipid biomarkers elucidate organic material (OM) sources and cycling within the water column. Biomarker composition and bulk properties (organic carbon (OC), nitrogen (N), OC/N ratio, CaCO3 and stable isotopes) were determined in suspended particles (30-4400 m, 100 mab) collected at Oceanic Flux Program site offshore Bermuda in April/November 2015 and October 2016, three periods of contrasting oceanographic conditions. Key lipid biomarkers were used to evaluate the relative importance of phytoplankton-, bacterial- and zooplankton-OM sources, diagenetic reprocessing, and the impact of upper ocean environmental forcing on the carbon pump. Additionally, we assessed benthic remineralization by comparing particles above and within the nepheloid layer (4400 m). N-fatty acids, n-alcohols and sterols comprise up to 85%, 12% and 7%, respectively, of total extractable lipids. Higher lipid concentrations in April vs November 2015 mirror seasonality in primary production, while change in sterol composition reflect shifts in phytoplankton community structure. In the mesopelagic zone, increased cholesterol/phytosterol ratios and percentages of C16 and C18 n-alcohols, odd-chain and branched n-fatty acids document a transition from algal to animal OM sources as well as bacterial reprocessing of labile OM. The impact of Hurricane Nicole (October 2016) on the mixed layer and subsequent increases in production/flux was evident in higher concentrations as well as greater depth penetration of particulate N and fresh/labile algal biomarkers (e.g. 18:5 ω3 and 22:6 ω3 polyunsaturated fatty acids) in the upper 1000 m. Suspended particles in the nepheloid layer had higher concentrations of OC and N and were more depleted in d13C than particles at 4200 m for all dates. While nepheloid lipid composition was similar for all dates, lipid concentrations in April 2015 (seasonal production peak) and October 2016 (hurricane physical forcing) were higher than in November 2015, consistent with the

  7. Metodología para la localización de un parque de tratamiento y disposición final de residuos sólidos de tipo regional desde una perspectiva multidimensional Methodology for the location of a treatment and solid waste disposal regional park, from a multidimensional perspective

    Directory of Open Access Journals (Sweden)

    Diana Elizabeth Valencia Londoño

    2010-07-01

    Full Text Available El manejo y disposición final de los residuos sólidos en el oriente antioqueño siempre ha sido una preocupación desde CORNARE y los entes territoriales.El artículo presenta los hallazgos de una investigación realizado por el grupo proyecto Ciudad de la facultad de Artes Integradas de la Universidad de San Buenaventura, cofinanciado por CORNARE, cuyo objetivo es presentar la metodología elaborada para la determinación de las áreas potenciales para el asentamiento de un parque de tratamiento y disposición final de residuos sólidos de tipo regional, teniendo como soporte la descripción, caracterización y análisis del ambiente (abiótico, biótico y socioeconómico en la subregión Valles de San Nicolás. Dicha propuesta se basa en un análisis matricial combinado con una herramienta SIG, que permitió evaluar diferentes sitios desde su viabilidad, ambiental, social, económica y física y entregar tanto a las Administraciones municipales como a la Corporación una estrategia metodológica que, incorporando lo planteado en el decreto 838, permita una toma de decisiones territoriales acertadas.The issue of handling and disposal of solid waste in eastern Antioquia has always been a topic of special concern and attention from CORNARE and local authorities. This article presents the findings of a project conducted by Universidad de San Buenaventura, School of Arts, City Project Group, founded by CORNARE, which aims to present the methodology developed for the identification of potential areas for the settlement of a park of Treatment and Disposal of Solid Waste Regional Type, having as support the description, characterization and analysis of (abiotic, biotic, and socio-economic environment in Valles de San Nicolás region. This proposal is based on a matrix analysis tool combined with GIS, which allowed us to evaluate different sites from its environmental, social, economic, and physical feasibility, and deliver to both local governments

  8. El legado filosófico-político del exilio español del 39

    Directory of Open Access Journals (Sweden)

    Sánchez Cuervo, Antolín

    2009-12-01

    Full Text Available The political thought of the Spanish exile of 1939 offers, seventy years later, fruitful and current perspectives. Besides a systematic and well-known work, linked to critical Marxism, such as the one of Adolfo Sánchez Vázquez, include other expressions, fragmented and meandering character, which focuses this paper. These were, namely, the early genealogy of fascism pointed out by Eugenio Ímaz and María Zambrano using different hermeneutical keys, but overlapping in linking it to the secularizing progression of modern reason. Second, the memory of own exile to both appealed against a complacent present about the victims of his more recent past, thereby leading to a debate between history and memory impregnated of political meaning. And third, the critique of contractarian logic pointed out by Eduardo Nicol on the horizon of a global techno-scientific rationality whose political implications affected the Spanish democracy instituted after the dictatorship.

    El pensamiento político del exilio español de 1939 ofrece, setenta años después, perspectivas fecundas y actuales. Junto a una obra sistemática y bien conocida, ligada al marxismo crítico, como la de Adolfo Sánchez Vázquez, cabe destacar otras expresiones, de carácter fragmentado y sinuoso, en las que se centra este trabajo. Tales fueron, concretamente, la temprana genealogía del fascismo que apuntaron Eugenio Ímaz y María Zambrano valiéndose de claves hermenéuticas diferentes aunque coincidentes en ligar dicho fenómeno a la progresión secularizadora de la razón moderna. En segundo lugar, la memoria del propio exilio a la que tanto uno como otro apelaron a contrapelo de un presente autocomplaciente respecto a las victimas de su pasado mas reciente, suscitando así un debate entre la historia y la memoria impregnado de significación política. Y, en tercer lugar, la crítica de la lógica contractualista apuntada por Eduardo Nicol en el horizonte de un racionalismo

  9. Distribución del ocelote (Leopardus pardalis en San Luis Potosí, México Distribution of the ocelot (Leopardus pardalis in San Luis Potosí, Mexico

    Directory of Open Access Journals (Sweden)

    Jesús Manuel Martínez-Calderas

    2011-09-01

    Full Text Available Para definir la distribución geográfica del ocelote en el estado de San Luis Potosí, México, se obtuvieron nuevos registros de la especie. El estudio se realizó de enero de 2007 a abril de 2009. Se obtuvieron 41 registros de ocelotes por medio de entrevistas y trampeo-fotográfico. Los registros se localizaron en comunidades vegetales de selva baja caducifolia (37%, matorral submontano (22%, bosque de encino (15%, selva mediana (10%, selva alta perennifolia, bosque mesófilo de montaña, bosque de pino-encino y matorral desértico micrófilo (10%. La presencia de ocelotes se ubicó en los municipios de Ciudad del Maíz, El Naranjo, Cerritos, Guadalcázar, San Nicolás Tolentino y Ciudad Valles en de elevaciones de 38 a 2 400 m snm. Los resultados de esta investigación sugieren una distribución del ocelote más hacia el oeste del estado respecto a su distribución original. El presente estudio definió nuevas regiones con presencia de ocelotes que pueden ser consideradas en el desarrollo de estrategias de conservación de la especie en el estado de San Luis Potosí.To determine the geographic distribution of ocelot in the state of San Luis Potosí, Mexico, we obtained new records. The study was conducted from January 2007 to April 2009. We recorded 41 ocelot records by interviews and camera-trapping. Ocelots records were located in tropical deciduous forest (37%, semitropical thornscrub (22%, oak forest (15%, tropical forest (10%, tall tropical deciduous forest, desert scrub, pine-oak forest and clouded forest (10%. Ocelot records were located in the municipalities of Ciudad del Maíz, El Naranjo, Cerritos, Guadalcazar, San Nicolás Tolentino and Ciudad Valles where the elevation ranged from 38 to 2 400 m. The evidence of this research suggests that ocelot range is more extended to the west than its original geographical range. This study defined new regions with presence of ocelots that may be considered to develop conservation strategies

  10. Book Reviews

    Directory of Open Access Journals (Sweden)

    William R. Roff

    1970-07-01

    Full Text Available - Jane Bunnag, Hans-Dieter Evers, Loosely structured social systems: Thailand in comparative perspective. Cultural Report Series no. 17, Yale University Southeast Asia Studies. New Haven 1969. 148 pp. - L. Sluimers, Milton E. Osborne, The French presence in Cochin-China and Cambodia: Rule and response (1859-1905. Cornell University Press, Ithaca and London 1970. XVIII + 379 pp. - H.J. Duller, G.L. Hicks, The Indonesian economy, 1950-1965; met een supplement tot 1967. Bibliographical Series No. 9, South-East Asia Studies, Yale University 1967. 248 p., n.p., G. McNicoll (eds. - J.W. de Vries, A. Mörzer Bruyns, Kamus singkatan dan akronim yang dipergunakan di Indonesia/Glossary of abbreviations and acronyms used in Indonesia, Ichtiar, Djakarta 1970. - William R. Roff, Abdul Majid Mohamed Mackeen, Contemporary Islamic legal organization in Malaya. Monograph Series No. 13. Yale University Southeast Asia Studies, New Haven, 1969. vii + 79 + 55 pp.

  11. REACHING THE COMPUTING HELP DESK

    CERN Multimedia

    Miguel MARQUINA; Roger WOOLNOUGH; IT/User Support

    1999-01-01

    The way to contact the Computing Help Desk (also known as 'UCO' and hosted by IT Division as an entry point for general computing issues) has been streamlined in order to facilitate access to it. A new telephone line and email address have been set: Phone number: 78888Email: Helpdesk@cern.chhopefully easier to remember. Both entries are operational since last December. The previous number and email address remain valid and have been turned into aliases of the above. However we encourage using the latter at your convenience from now on. For additional information please see the article published at the CERN Computing Newsletter 233:http://consult.cern.ch/cnl/233/art_uco.htmlDo not hesitate to contact us (by email to User.Relations@cern.ch) for additional information or feedback regarding this matter.Nicole Cremel, Miguel Marquina, Roger WoolnoughIT/UserSupport

  12. Hopf solitons in the AFZ model

    International Nuclear Information System (INIS)

    Gillard, Mike

    2011-01-01

    The Aratyn–Ferreira–Zimerman (AFZ) model is a conformal field theory in three-dimensional space. It has solutions that are topological solitons classified by an integer-valued Hopf index. There exist infinitely many axial solutions which have been found analytically. Static axial, knot and linked solitons are found numerically using a modified volume preserving flow for Hopf index one to eight, allowing for comparison with other Hopf soliton models. Solutions include a static trefoil knot at Hopf index five. A one-parameter family of conformal Skyrme–Faddeev models, consisting of linear combinations of the Nicole and AFZ models, are also investigated numerically. The transition of solutions for Hopf index four is mapped across these models. A topological change between linked and axial solutions occurs, with fewer models (or a limited range of parameter values) permitting axial solitons than linked solitons at Hopf index four

  13. Peer feedback: Using diciplinary-specific teaching formats as "bridges" to enable student engagement

    DEFF Research Database (Denmark)

    Jensen, Tine Wirenfeldt; Dankl, Kathrina

    2017-01-01

    Introduction Peer feedback has been proven to significantly strengthen students’ academic writing skills as well as foster meta-cognitive awareness on learning processes (Gibbs et al. 2004, Nicol et. al 2006). In order to unleash this potential, a collaborative and trusting ethos is required...... disciplinary-specific teaching formats and using these as “bridges” to enable students’ active engagement and unlock student’s co-creation skills. Method The proposed method has been applied at the Design School in Kolding at a course initiated as a part of the Master’s thesis supervision. As a method...... for a synopsis, and peer feedback was introduced for ‘shaping and co-creating’ first drafts of a synopsis. Both peer feedback and the concept of creative constraints (see freewriting format), are commonly used in design as methods to spur creativity. Results According to students own written evaluations (fifteen...

  14. Himno a Barranquilla

    Directory of Open Access Journals (Sweden)

    Amira de la Rosa

    2013-05-01

    Full Text Available Barranquilla, prócera e inmortal Ceñida de agua y madurada al sol Savia joven del árbol nacional.   Del jubiloso porvenir crisol Ilusión de Caribe blanco-azul De Colombia tendida en el umbral Da su voz y su músculo al progreso Barranquilla, prócera e inmortal.   Barrancas de San Nicolás con el Magdalena detrás.   Coronada de firme amanecer  te conduce en su espalda el porvenir: las sirenas de fábrica y taller son rumor arterial de tu existir.   Barranquilla sabe cantar  y sobre el yunque martillar.   Tajamares de Bocas de Ceniza Cuchillada del río sobre el mar al Caribe central colombianiza  tu robusta aptitud de navegar.   Amira de la Rosa Poetisa y dramaturga colombiana (1903-1974 (Fundadora del colegio Gabriela Mistral de Barranquilla, 1926

  15. Iglesia y evangelización en las indias durante el gobierno de Nicolás de Ovando (1502-1509

    Directory of Open Access Journals (Sweden)

    Mira Caballos, Esteban

    2001-12-01

    Full Text Available This article studies more than one hundred sermons that were preached in six towns of Mexico from 1622 to 1777. These sermons prove the importance that preachers had in the formation of a national concience joined to the veneration for the Virgin of Guadalupe.

    En el presente trabajo se estudian más de cien sermones predicados en seis ciudades de México entre los años 1622 y 1777. Su contenido demuestra la importancia que los predicadores tuvieron en la formación de una conciencia nacional mexicana ligada a la devoción de la Virgen de Guadalupe.

  16. Prácticas curativas y plantas medicinales: un acercamiento a la etnomedicina de San Nicolás, México

    Directory of Open Access Journals (Sweden)

    María Cristina Chávez Mejía

    2017-01-01

    Full Text Available Existe interés por las prácticas curativas de la medicina tradicional como forma de curación/ sanación alterna y complementaria. El objetivo del artículo es documentar las prácticas curativas y las plantas medicinales que actualmente se utilizan en una comunidad rural del Estado de México. Desde la etnomedicina, se abordan las explicaciones cognitivas de los sujetos que participan del binomio salud-enfermedad. Se utilizó el método etnográfico para obtener y sistematizar información sobre las percepciones acerca de las prácticas curativas y plantas medicinales. Las prácticas son el resultado del conocimiento acumulado sobre el ambiente y se llevan a cabo por el interés de ayudar, más que por beneficio económico. Se concluye que la herbolaria es un indicativo de: 1 la pervivencia de la cosmovisión mesoamericana para tratar enfermedades de cuerpo y espíritu; 2 se privilegia una atención integral del paciente y 3 el ambiente físico que rodea a las personas es un botiquín bio-cultural.

  17. A revision of the haploporinae nicoll, 1914 (digenea: haploporidae) from mullets (mugilidae): Dicrogaster Looss, 1902 and Forticulcita overstreet, 1982.

    Science.gov (United States)

    Blasco-Costa, Isabel; Montero, Francisco E; Balbuena, Juan Antonio; Raga, Juan Antonio; Kostadinova, Aneta

    2009-03-01

    The status of the nominal species of Dicrogaster is re-assessed by means of a comparative morphological study based on newly collected material from the western Mediterranean and a critical evaluation of the published data. D. perpusilla Looss, 1902 (type-species) and D. contracta Looss, 1902 are redescribed on the basis of new material from Liza spp. D. fragilis Fernández Bargiela, 1987 is considered a junior synonym of D. fastigata Thatcher & Sparks, 1958 and D. maryutensis Al-Bassel, 1990 is considered to be nomen nudum. A key to the recognised species of Dicrogaster is presented. A new species of Forticulcita Overstreet, 1982 is described from Mugil cephalus L. in the Spanish Mediterranean and differentiated from the type-species, F. glabra Overstreet, 1982, and the recently described F. mugilis Hassanine, 2007 by its significantly smaller body size and most of its metrical data. The new species, F. gibsoni n. sp., is characterised by a narrow 'neck' region anterior to the genital pore and a long striated 'tail' region in the hindbody which is devoid of organs, such that the bulk of the uterus is restricted to the anterior half of the hindbody and the testis is located more anteriorly. F. gibsoni differs from F. glabra in having a longer forebody, smaller sucker width ratio and larger eggs, and from F. mugilis in having a smaller sucker width ratio, a hermaphroditic sac much longer than the ventral sucker and smaller eggs. The three Mediterranean forms, D. perpusilla, D. contracta and F. gibsoni are further distinguished by multivariate analyses. Keys to the species of both genera are presented.

  18. A revision of the Haploporinae Nicoll, 1914 (Digenea: Haploporidae) from mullets (Mugilidae): Haploporus Looss, 1902 and Lecithobotrys Looss, 1902.

    Science.gov (United States)

    Blasco-Costa, Isabel; Gibson, David I; Balbuena, Juan Antonio; Raga, Juan Antonio; Kostadinova, Aneta

    2009-06-01

    The status of the nominal species of Haploporus Looss, 1902 and Lecithobotrys Looss, 1902 is re-assessed by means of a comparative morphological study based on newly collected specimens from the western Mediterranean, the re-examination of museum material and a critical evaluation of published data. H. benedeni (Stossich, 1887) (type-species) is described and H. lateralis Looss, 1902 is considered to be its junior synonym. Additional data are given for H. pseudoindicus Rekharani & Madhavi, 1985, H. spinosus Machida, 1996 and H. magnisaccus Machida, 1996. Species parasitising Valamugil spp. from the Indo-West Pacific region, H. indicus Rekharani & Madhavi, 1985, H. spinosus, H. magnisaccus, H. mugilis Liu & Yang, 2002 and H. muscolosaccus Machida, 2003, are considered incertae sedis with respect to their generic affiliation. H. pacificus (Manter, 1963) (syn. Neohaploporus pacificus Manter, 1963), H. pseudoindicus and H. musculosaccus are designated as species inquirendae and H. lossii Al-Bassel, 1990 is considered to be a nomen nudum. Lecithobotrys putrescens Looss, 1902 is described based on newly collected material from Liza spp. Pseudolecithobotrys n. g. is erected to accommodate Lecithobotrys stomachicola Machida, 1996, as P. stomachicola (Machida, 1996) n. comb., from the North Pacific. L. aegyptiacus Hassan, El-Aziz, Khidr & Abu Samak, 1990 is considered to be a synonym of Saccocoelium tensum Looss, 1902, and L. brisbanensis (Martin, 1974) (syn. Paralecithobotrys brisbanensis Martin, 1974), L. vitellosus Sharma & Gupta, 1970 and L. suezcanali Nisreen Ezz El-Dien, Abdel-Rahman, El-Gawady, Imam & Fahmy, 1990 are regarded as species inquirendae. New generic diagnoses are presented for both Haploporus and Lecithobotrys.

  19. Nicole Dufournaud, Rôles et pouvoirs des femmes au XVIe siècle dans la France de l'Ouest

    Directory of Open Access Journals (Sweden)

    Nicole Dufournaud

    2007-11-01

    Full Text Available Dans les années 1970, Joan Kelly posait la question : « Les femmes ont-elles connu une Renaissance ? ». L'historienne américaine y répondait par la négative. Revenir sur cette question, c'est chercher à comprendre l'évolution du statut des femmes. Grâce à une étude localisée sur un espace géographique relativement homogène, nous montrons en quoi les femmes ont compté dans la dynamique sociale et économique de la Renaissance et en quoi elles y ont gagné et perdu.La thèse se découpe en six chap...

  20. A revision of the Haploporinae Nicoll, 1914 (Digenea: Haploporidae) from mullets (Mugilidae): Haploporus Looss, 1902 and Lecithobotrys Looss, 1902

    Czech Academy of Sciences Publication Activity Database

    Blasco-Costa, I.; Gibson, D. I.; Balbuena, J. A.; Raga, J. A.; Kostadinova, Aneta

    2009-01-01

    Roč. 73, č. 2 (2009), s. 107-133 ISSN 0165-5752 R&D Projects: GA MŠk LC522 Institutional research plan: CEZ:AV0Z60220518 Keywords : taxonomic revision * Haploporidae * Haploporus * Lecithobothrys * Mugilidae Subject RIV: GJ - Animal Vermins ; Diseases, Veterinary Medicine Impact factor: 0.911, year: 2009

  1. Ecclesiastical Architecture and the Castilian Crisis of the Seventeenth Century: Seville Cathedral and the Church of the Sagrario.

    Directory of Open Access Journals (Sweden)

    Sing d'Arcy

    2014-12-01

    Full Text Available When it came time for the critics and historiographers of the late eighteenth and early nineteenth centuries to write the grand narrative of Spanish architecture, the decadence of Habsburg monarchy, economy and society was paralleled to the decline of the noble art itself. The completion of the Escorial in 1584 loomed more like an enormous granite epitaph for Spanish architectural production than the promise of a New Jerusalem. For seventeenth-century architects and theoreticians, like Fray Lorenzo de San Nicolás, and nineteenth-century commentators, such as Agustín Ceán Bermúdez, the intromission of painters, joiners, silversmiths and other guilds into the realm of architectural design was seen as the principal corruptive force which manifested itself in the unpardonable horrors of the Baroque. These negative topoi have, in many cases, found their way into the contemporary historiography of Spanish architecture of the period, typically depicted as all surface and no space, relegating it to a place lesser importance.

  2. La pintura mural en la Granada del XVIII.

    Directory of Open Access Journals (Sweden)

    Ana María Gómez Román

    2016-01-01

    Full Text Available El camino hacia la revalorización de la pintura mural a lo largo del siglo XVIII en la ciudad de Granada arranca con la figura del arzobispo Martín de Ascargorta (1693-1719. El gusto impuesto por este prelado supuso un cambio durante la primera mitad de este siglo en el desarrollo de los programas decorativos bajo las directrices de Acisclo Antonio Palomino y José Risueño que tendría su prolongación con la actividad de pintores como Martín de Pineda, José Hidalgo, Diego Sánchez Saravia o Tomás Ferrer. Este gusto por la pintura mural culminaría a finales de la centuria con el ciclo de las hazañas del Quijote del Palacio del Cuzco en Víznar, relacionado también con otro arzobispo, Juan Manuel Moscoso (1789-1811 y realizado por Nicolás Martín Tenllado, José de Medina y Antonio Jiménez.

  3. Sociedad, familia y género en Santafé a finales de la colonia

    Directory of Open Access Journals (Sweden)

    Guiomar Dueñas

    1993-01-01

    Full Text Available En 1770, Nicolás Burgos, natural de Santafé, hijo legítimo de Carlos Gregorio Burgos y Josefa Domínguez, hallándose enfermo pero en sano juicio, desea poner sus cosas en orden antes de morir. Declara que fue casado "como manda la Santa Iglesia" con Salvadora García, con quien tuvo 16 hijos, de los cuales murieron 11 a temprana edad. Declara que su esposa trajo al matrimonio algunos pocos bienes, entre ellos un "pedacito de tierra" en Tausa, y él aportó tres muías, un caballo y una silla de montar. Los bienes aumentaron, gracias al trabajo de los dos; a la muerte de su consorte, "según manda la justicia ordinaria" se realizó un inventario de los bienes tocándole a cada hija (fueron mujeres las sobrevivientes por parte materna 100 patacones, y por parte paterna 65 pesos y 5 reales.

  4. A propósito de unas versiones de La Sagrada Familia con los santos «Juanitos» de Juan de Juanes

    Directory of Open Access Journals (Sweden)

    Mateo Gómez, Isabel

    2002-03-01

    Full Text Available Desde el año 1961 consta en el Archivo fotográfico del Instituto Amatller de Barcelona una Sagrada Familia con los santos «Juanitos» (fig. 1, en colección privada madrileña. Un año después, José Luis Alonso Misol la publicó en un artículo sobre Pintura española en colecciones madrileñas, aportando el nombre del coleccionista, Sr. Fernández López, y destacando que se trataba de una de las mejores obras de Juan de Juanes, de la que hay otras versiones con algunas variantes, poniendo como ejemplo de ellas la de la Academia de San Fernando (fig. 3. En esta línea podría considerarse la pintada por Nicolás Borras (fig. 4, de la colección Grases de Barcelona donde se encontraba en 1916, y en la que se advierten ambas influencias.…

  5. Detection and identification of cutaneous leishmaniasis isolates by culture, Polymerase chain reaction and sequence analyses in Syrian and Central Anatolia patients.

    Science.gov (United States)

    Beyhan, Yunus E; Karakus, Mehmet; Karagoz, Alper; Mungan, Mesut; Ozkan, Aysegul T; Hokelek, Murat

    2017-09-01

    To characterize the cutaneous leishmaniasis (CL) isolates of Syrian and Central Anatolia patients at species levels. Methods: Skin scrapings of 3 patients (2 Syrian, 1 Turkish) were taken and examined by direct examination, culture in Novy-MacNeal-Nicole (NNN) medium, internal transcribed spacer polymerase chain reaction and sequence analysis (PCR). Results:According to microscopic examination, culture and PCR methods, 3 samples were detected positive. The sequencing results of all isolates in the study were identified as Leishmania tropica. The same genotypes were detected in the 3 isolates and nucleotide sequence submitted into GenBank with the accession number: KP689599. Conclusion: This finding could give information about the transmission of CL between Turkey and Syria. Because of the Syrian civil war, most of the Syrian citizens circulating in Turkey and different part of Europe, this can be increase the risk of spreading the disease. So, prevention measurements must be taken urgently.

  6. Detection and identification of cutaneous leishmaniasis isolates by culture, Polymerase chain reaction and sequence analyses in Syrian and Central Anatolia patients

    Directory of Open Access Journals (Sweden)

    Yunus E. Beyhan

    2017-09-01

    Full Text Available Objectives: To characterize the cutaneous leishmaniasis (CL isolates of Syrian and Central Anatolia patients at species levels. Methods: Skin scrapings of 3 patients (2 Syrian, 1 Turkish were taken and examined by direct examination, culture in Novy-MacNeal-Nicole (NNN medium, internal transcribed spacer polymerase chain reaction and sequence analysis (PCR. Results:According to microscopic examination, culture and PCR methods, 3 samples were detected positive. The sequencing results of all isolates in the study were identified as Leishmania tropica. The same genotypes were detected in the 3 isolates and nucleotide sequence submitted into GenBank with the accession number: KP689599. Conclusion: This finding could give information about the transmission of CL between Turkey and Syria. Because of the Syrian civil war, most of the Syrian citizens circulating in Turkey and different part of Europe, this can be increase the risk of spreading the disease. So, prevention measurements must be taken urgently.

  7. $\\beta$-delayed neutrons from oriented $^{137,139}$I and $^{87,89}$Br nuclei

    CERN Multimedia

    We propose a world-first measurement of the angular distribution of $\\beta$‐delayed n and $\\gamma$-radiation from oriented $^{137, 139}$I and $^{87,89}$Br nuclei, polarised at low temperature at the NICOLE facility. $\\beta$­-delayed neutron emission is an increasingly important decay mechanism as the drip line is approached and its detailed understanding is essential to phenomena as fundamental as the r‐process and practical as the safe operation of nuclear power reactors. The experiments offer sensitive tests of theoretical input concerning the allowed and first­‐forbidden $\\beta$‐decay strength, the spin-density of neutron emitting states and the partial wave barrier penetration as a function of nuclear deformation. In $^{137}$I and $^{87}$Br the decay feeds predominantly the ground state of the daughters $^{136}$Xe and $^{86}$Kr whereas in $^{139}$I and $^{89}$Br we will explore the use of n-$\\gamma$- coincidence to study neutron transitions to the first and second excited states in the daughters...

  8. Magnetic Moment of $^{59}$Cu

    CERN Multimedia

    2002-01-01

    Experiment IS358 uses the intense and pure beams of copper isotopes provided by the ISOLDE RILIS (resonance ionization laser ion source). The isotopes are implanted and oriented in the low temperature nuclear orientation set-up NICOLE. Magnetic moments are measured by $\\beta$-NMR. Copper (Z=29), with a single proton above the proton-magic nickel isotopes provides an ideal testground for precise shell model calculations of magnetic moments and their experimental verification. In the course of our experiments we already determined the magnetic moments of $^{67}$Ni, $^{67}$Cu, $^{68g}$Cu, $^{69}$Cu and $^{71}$Cu which provide important information on the magicity of the N=40 subshell closure. In 2001 we plan to conclude our systematic investigations by measuring the magnetic moment of the neutron-deficient isotope $^{59}$Cu. This will pave the way for a subsequent study of the magnetic moment of $^{57}$Cu with a complementary method.

  9. Search for a tensor component in the weak interaction Hamiltonian

    CERN Document Server

    Soti, Gergely

    The search for physics beyond the standard model can, besides in high-energy experiments such as the ones at the LHC accelerator, also be carried out at lower energies. Measurements of correlation coefficients in neutron and nuclear b decay constitute a reliable and model-independent method for such efforts. The topic of this thesis is the precision measurement of the beta asymmetry parameter A. It was measured in the decay of 67Cu, which proceeds via a pure Gamow-Teller b transition, thus its A parameter is sensitive to possible tensor type currents in the weak interaction. The experiment was performed at the NICOLE setup in ISOLDE (CERN), using the technique of low temperature nuclear orientation. The b particles were observed with custom made planar high purity germanium detectors operating at around 10 K. The beta asymmetry of 68Cu was measured on-line for normalization purposes. Geant4 simulations were used to gain control over systematic effects such as electron scattering on the particle detectors. As...

  10. Effect of particle-core-vibration coupling near the double closed $^{132}$Sn nucleus from precise magnetic moment measurements

    CERN Multimedia

    Postma, H; Heyde, K; Walker, P; Grant, I; Veskovic, M; Stone, N; Stone, J

    2002-01-01

    % IS301 \\\\ \\\\ Low temperature nuclear orientation of isotope-separator implanted short-lived radio-isotopes makes possible the measurements of nuclear magnetic dipole moments of oriented ground and excited states with half-lives longer than a few seconds. Coupling schemes characterizing the odd nucleons and ground-state deformations can be extracted from the nuclear moments. \\\\ We thus propose to measure the magnetic dipole moments of $^{127-133}$Sb to high precision using NMR/ON at the NICOLE facility. With (double magic +1) $^{133}$Sb as the reference, the main aim of this experiment is to examine whether the collective component in the 7/2$^+$ Sb ground state magnetic dipole moment varies as expected according to particle-core coupling calculations carried out for the Sb (Z=51) isotopes. Comparison of the 1-proton-particle excitations in Sb to 1-proton-hole states in In nuclei will shed light on differences between particle and hole excitations as understood within the present model. Comparison of ...

  11. Proposed strategy for improving capulín cultivation in the municipalities of Domingo Arenas, Calpan and San Nicolas de los Ranchos

    Directory of Open Access Journals (Sweden)

    Luz María Páez Reyes

    2013-01-01

    Full Text Available Currently the municipalities of Domingo Arenas, Calpan and San Nicolás de los Ranchos Puebla State, conditions and have a favorable climate for growing capulín, however, not being given adequate management value the crop, This causes the yields are low and its economic importance is unnoticed. The aim of the investigation was "explore how to improve the economic and productive use capulín through the revaluation of the same by the producers, because of the advantages offered by the cultivation in its management and low investment”. For data collection a semistructured interview wasapplied to 15 key informants five municipality respectively. For data analysis tool was used the problem tree and a SWOT. Among the outstanding results we found that capulín has opportunities that can be exploited as an economic alternative for low-income producers or for the unemployed, because their characteristics and management can be easily cultivated.

  12. Equidistribution for Nonuniformly Expanding Dynamical Systems, and Application to the Almost Sure Invariance Principle

    Science.gov (United States)

    Korepanov, Alexey

    2017-12-01

    Let {T : M \\to M} be a nonuniformly expanding dynamical system, such as logistic or intermittent map. Let {v : M \\to R^d} be an observable and {v_n = \\sum_{k=0}^{n-1} v circ T^k} denote the Birkhoff sums. Given a probability measure {μ} on M, we consider v n as a discrete time random process on the probability space {(M, μ)} . In smooth ergodic theory there are various natural choices of {μ} , such as the Lebesgue measure, or the absolutely continuous T-invariant measure. They give rise to different random processes. We investigate relation between such processes. We show that in a large class of measures, it is possible to couple (redefine on a new probability space) every two processes so that they are almost surely close to each other, with explicit estimates of "closeness". The purpose of this work is to close a gap in the proof of the almost sure invariance principle for nonuniformly hyperbolic transformations by Melbourne and Nicol.

  13. The Vatican museum and the organic natural products. The Raphael's frescoes and the "Last Judgment" by Nicolò and Giovanni.

    Science.gov (United States)

    Gabrielli, Nazzareno; Guiso, Marcella; Bianco, Armandodoriano

    2017-05-25

    In the second half of the 90s, alongside the restoration works of the Quattrocentisti (fifteenth century painters) in the Sistine Chapel, it also carried out the restoration of the frescoes of the Stanze di Raffaello. The results of scientific investigations conducted by the Scientific Research Laboratory of the Vatican Museums, previously presented in some assays of study, are summarised and presented in this letter to the Editor for the special issue of Natural Product Research: Natural Products in Cultural Heritage.

  14. Envejecimiento activo en personas con enfermedad de Alzheimer en la Residencia Nicolás Rodríguez de Olmedo (Valladolid)

    OpenAIRE

    Callejo Casquete, Amanda

    2014-01-01

    Debido al aumento considerable de la población anciana en la actualidad y a su vinculación con las diferentes demencias, y en especial con la enfermedad del Alzheimer, el presente trabajo de fin de grado pretende que la sociedad tome conciencia de la importancia del envejecimiento activo, proyectando una imagen positiva de las personas mayores. El presente trabajo, haciendo hincapié en la importancia que conlleva desarrollar unos hábitos de vida saludable tanto física como mentalmente, plante...

  15. Accessing and assessing young learner’s mathematical dispositions

    Directory of Open Access Journals (Sweden)

    mellony Graven

    2012-07-01

    Full Text Available It is argued in this paper that there is an absence of literature relating to research on learner mathematical dispositions, particularly with young learners. Drawing on Kilpatrick, Swafford and Findell’s (2001 five interrelated strands of mathematical proficiency, which include: conceptual understanding, procedural fluency, strategic competence, adaptive reasoning and productive disposition, it is argued that there has been little engagement with productive disposition in the field of mathematics education and how we might access and assess this strand. Despite competence in all strands being essential for mathematical proficiency, literature and assessments that seek to establish learner levels of mathematical proficiency have tended to focus on the first four and have neglected the last; productive disposition. Finding ways in which to access student mathematical learning dispositions can be challenging, especially with young learners who struggle to articulate their views. An instrument is shared that the author has designed with doctoral fellow, Debbie Stott, in order to access and assess the productive disposition of learners participating in maths clubs run within the South African Numeracy Chair. The findings that emerge in one Grade 3 club with six learners is shared. These findings are related to the data collected through instruments that assess the other four strands of mathematical proficiency. This enables a holistic picture of learner’s mathematical proficiency as intended in the conceptualisation of the interrelated five strands of proficiency.

  16. "One of the Most Uniform Races of the Entire World": Creole Eugenics and the Myth of Chilean Racial Homogeneity.

    Science.gov (United States)

    Walsh, Sarah

    2015-11-01

    This article illuminates why Nicolás Palacios's 1904 monograph, Raza chilena: Libro escrito por un Chileno i para los Chilenos [Chilean Race: A Book Written by a Chilean for Chileans], is central to the creation of a myth of Chilean racial homogeneity at the turn of the twentieth century. Placing Palacios in the context of Latin American eugenic discourse, it demonstrates how he selected a specific racial origin story in order to accommodate his belief in racial hierarchy while also depicting race mixing in a positive light. Specifically, the article highlights how the myth of Chilean racial homogeneity elided the difference between the term "mestizo," which was applied to people of mixed racial heritage, and "white." I contend that Palacios sought to differentiate Chileans from other Latin Americans by emphasizing their racial distinctiveness. The article therefore highlights that Latin American eugenics was concerned with the creation of national narratives that historicized particular racial mixtures in order to reify and affirm national differences. As such, it connects to literature regarding the history of eugenics, race, nation, and the creation of whiteness.

  17. A propósito de “El cuerpo como máquina. La medicalización de la fuerza de trabajo en Chile”. Sobre el dispositivo médico y su alcance

    Directory of Open Access Journals (Sweden)

    Hugo Nicolás Sir Retamales

    2014-04-01

    Full Text Available En la siguiente reseña, se hace referencia al libro del autor Nicolás Fuster “El cuerpo como máquina. La medicalización de la fuerza de trabajo en Chile”, publicado en Santiago de Chile el año 2013 por la editorial Ceibo. El presente trabajo constituye una modificación a la presentación del libro, y se exponen en él argumentos centrales del libro, con una lógica argumentativa que intenta mostrar la relevancia a su vez como fuente documental, y como principio de interrogación a las problemáticas actuales, respecto a las formas de gobierno contemporáneas. Una de los elementos a los que se arriba es la ambivalencia que encierra el proceso de medicalización, como bien sucede con el despliegue de otros dispositivos, entre las instancias de control heterónomo, y las posibilidades auformativas no totalmente cooptadas, que dan espacio a relaciones diversas con la institucionalidad, y por tanto, lugar para modificar los dispositivos

  18. Proyecto multidisciplinar `Marte nos visita'

    Science.gov (United States)

    Merlo, D.; Merlo, N.; Parodi, B.; Garis, A.; Peralta, G.; Rovessi, V.; Urrutia, S.; Calderón, J.; Bustos Fierro, I.; Melia, R.

    The planets Earth and Mars reached in August 2003 the most approximation in the last 58,000 years. In order to that we carried out a transversal study of red planet, joining the knowledges from several subjects of second school year of unified basic cycle (eighth basic general education) at I.P.E.M. No 249 "Nicolás Copérnico" (a public secondary institution from Córdoba, Argentine). In this study, activities in accordance with current contents has been proposed by common consents of each teacher. Besides, students visited Córdoba Astronomical Observatory in order to search informations and received a multimedia exposition about of astronomical event and a performance of the "Carl Sagan" Moveable Planetary. Finally, each student carried out practical works and wrote an integrative report, which one has been evaluated and exposed at ExpoIPEM 2003, an annual exhibition of several specialities that Institution offers in its specialization cycle (10-12 grade), where the annual students' activities are exhibited too (workshops, school projects, etc.).

  19. Spotlight on ixazomib: potential in the treatment of multiple myeloma

    Directory of Open Access Journals (Sweden)

    Muz B

    2016-01-01

    Full Text Available Barbara Muz,1 Rachel Nicole Ghazarian,1,2 Monica Ou,1,3 Micah John Luderer,1 Hubert Daniel Kusdono,1,2 Abdel Kareem Azab1 1Department of Radiation Oncology, Cancer Biology Division, Washington University in St Louis School of Medicine, 2Department of Pharmaceutical and Administrative Sciences, St Louis College of Pharmacy, 3Department of Biology, St Louis University, St Louis, MO, USA Abstract: Despite the significant therapeutic advances achieved with proteasome inhibitors (PIs such as bortezomib and carfilzomib in prolonging the survival of patients with multiple myeloma, the development of drug resistance, peripheral neuropathy, and pharmacokinetic limitations continue to pose major challenges when using these compounds. Ixazomib is a second-generation PI with improved activity over other PIs. Unlike bortezomib and carfilzomib, which are administered by injection, ixazomib is the first oral PI approved by US Food and Drug Administration. This review discusses the biochemical properties, mechanisms of action, preclinical efficacy, and clinical trial results leading to the US Food and Drug Administration approval of ixazomib. Keywords: proteasome inhibitor, oral administration, biological mechanism, clinical trials

  20. Nuclear magnetic moment of 69As from on-line β-NMR on oriented nuclei

    International Nuclear Information System (INIS)

    Golovko, V.V.; Kraev, I.S.; Phalet, T.; Severijns, N.; Delaure, B.; Beck, M.; Kozlov, V.Yu.; Lindroth, A.; Coeck, S.; Zakoucky, D.; Venos, D.; Srnka, D.; Honusek, M.; Herzog, P.; Tramm, C.; Koester, U.

    2005-01-01

    A precise value for the magnetic moment of the 69 As 5/2 - ground state has been obtained from nuclear magnetic resonance on oriented nuclei (NMR/ON) using the NICOLE 3 He- 4 He dilution refrigerator setup at ISOLDE/CERN. The NMR/ON signal was observed by monitoring the anisotropy of the 69 As β particles. The center frequency ν[B ext =0.0994(10)T]=169.98(9) MHz corresponds to μ[ 69 As]=+1.6229(16)μ N . This result differs considerably from the πf 5/2 single-particle value obtained with g factors for a free proton but is in reasonable agreement with the value obtained with effective g factors and with values from a core polarization calculation and from calculations in the framework of the interacting boson-fermion model. Assuming a single exponential spin-lattice relaxation behavior a relaxation time T 1 ' =10(25) s was observed for 69 AsFe -bar at a temperature of about 20 mK in a magnetic field B=0.1 T

  1. Some historic and current aspects of plasma diagnostics using atomic spectroscopy

    Science.gov (United States)

    Hutton, Roger; Zou, Yaming; Andersson, Martin; Brage, Tomas; Martinson, Indrek

    2010-07-01

    In this paper we give a short introduction to the use of atomic spectroscopy in plasma diagnostics. Both older works and exciting new branches of atomic physics, which have relevance to diagnostics, are discussed. In particular we focus on forbidden lines in Be-like ions, lines sensitive to magnetic fields and levels which have a lifetime dependence on the nuclear spin of the ion, i.e. f-dependent lifetimes. Finally we mention a few examples of where tokamaks, instead of needing atomic data, actually provide new data and lead to developments in atomic structure studies. This paper is dedicated to the memory of Nicol J Peacock (1931-2008), a distinguished plasma scientist who contributed much to the field of spectroscopy applied to plasma, and in particular, fusion plasma diagnostics. During the final stages of the preparation of this paper Professor Indrek Martinson passed away peacefully in his sleep on 14 November 2009. Indrek will be greatly missed by many people, both for his contributions to atomic spectroscopy and for his great kindness and friendliness, which many of us experienced.

  2. INCIDENCIA DE LA VELOCIDAD DE APLICACIÓN DE CARGA EN LA RESISTENCIA AL CORTE NO DRENADO DE SUELOS RESIDUALES DE ANFIBOLITA EN EL VALLE DE SAN NICOLÁS, ANTIOQUIA (COLOMBIA

    Directory of Open Access Journals (Sweden)

    Manuel Alonso Builes Brand

    Full Text Available Los suelos residuales por su proceso de formación tienen unas características especiales que no están caracterizados dentro de la mecánica de suelos tradicional dedicada a los suelos sedimentarios. El proceso de meteorización según los ciclos de exposición a los que sean expuestos presentan variaciones en su composición y comportamiento mecánico. Suelos residuales de anfibolita localizados en el Valle de San Nicolás, cerca de la ciudad de Medellín han sido recuperados y ensayados. La variación de la velocidad del ensayo de corte versus la resistencia al corte no drenada ha sido evaluada mediante la realización de ensayos de corte UU sobre muestras inalteradas recuperadas mediante la utilización de Tubos Shelby de pared delgada, se presentan las gráficas de variación del esfuerzo cortante, la cohesión y ángulo de fricción versus la velocidad y su incidencia en el diseño.

  3. BASE COMPOSITION OF THE DEOXYRIBONUCLEIC ACID OF SULFATE-REDUCING BACTERIA.

    Science.gov (United States)

    SIGAL, N; SENEZ, J C; LEGALL, J; SEBALD, M

    1963-06-01

    Sigal, Nicole (Laboratoire de Chimie Bactérienne du CNRS, Marseille, France), Jacques C. Senez, Jean Le Gall, and Madeleine Sebald. Base composition of the deoxyribonucleic acid of sulfate-reducing bacteria. J. Bacteriol. 85:1315-1318. 1963-The deoxyribonucleic acid constitution of several strains of sulfate-reducing bacteria has been analytically determined. The results of these studies show that this group of microorganisms includes at least four subgroups characterized by significantly different values of the adenine plus thymine to guanine plus cytosine ratio. The nonsporulated forms with polar flagellation, containing both cytochrome c(3) and desulfoviridin, are divided into two subgroups. One includes the fresh-water, nonhalophilic strains with base ratio from 0.54 to 0.59, and the other includes the halophilic or halotolerant strains with base ratio from 0.74 to 0.77. The sporulated, peritrichous strains without cytochrome and desulfoviridin ("nigrificans" and "orientis") are distinct from the above two types and differ from each other, having base ratios of 1.20 and 1.43, respectively.

  4. Bortezomib in the management of multiple myeloma

    Directory of Open Access Journals (Sweden)

    Jacob P Laubach

    2009-09-01

    Full Text Available Jacob P Laubach, Constantine S Mitsiades, Teru Hideshima, Robert Schlossman, Dharminder Chauhan, Nikhil Munshi, Irene Ghobrial, Nicole Carreau, Kenneth C Anderson, Paul G RichardsonDepartment of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts, USAAbstract: Multiple myeloma (MM is a B-cell malignancy characterized by clonal expansion of plasma cells within the bone marrow, the presence of a serum and/or urine monoclonal protein, lytic bone lesions, and anemia. On a cellular level, the disease is characterized by complex interactions between tumor cells and the surrounding bone marrow microenvironment. Understanding of the relationship between malignant plasma cells and the microenvironment has sparked ongoing efforts to develop targeted therapeutic agents for treatment of this disease. The successful development of the first-in-class small-molecule proteasome inhibitor bortezomib occurred as a result of these efforts. This review focuses on the rationale for bortezomib therapy in the treatment of patients with newly diagnosed and relapsed MM, important treatment-related side effects, and future directions for use of bortezomib and other, emerging proteasome inhibitors.Keywords: multiple myeloma, bortezomib, stem cell transplantation, peripheral neuropathy

  5. Lykkes peer-feedback altid?

    DEFF Research Database (Denmark)

    Jørgensen, Bente Mosgaard

    Agenda. International Journal of English Studies, 10(2), 171-184. doi:10.6018/ijes.10.2.119251 Lee, I. (2013). Research into Practice: Written Corrective Feedback. Language Teaching, 46(2), 108-119. doi:10.1017/S0261444812000390 Nicol, D. (2014). Guiding Principles for Peer Reveiw: Unlocking Learner...... Aarhus Universitet tilbydes derfor en række større og mindre opgaver, der skal give dem mulighed for at træne denne evne (se paper I, Jensen, in press, 2018). Nogle af de mindre opgaver inkluderer brugen af peer-feedback. Opgaverne afvikles via systemet Peergrade, hvor de studerende online bedømmer...... til at være, (3) pege på hvilke fordele og udfordringer der er med at anvende peer-feedback i det anvendte set-up på den pågældende uddannelse og (4) foreslå hvilke krav der må stilles til et system, der skal understøtte en korrektiv peer feedback proces ? Bredt teoretisk er jura-casen et eksempel på...

  6. New year, new Medical Service!

    CERN Multimedia

    2002-01-01

    The Medical Service. From left to right : Nicole De Matos, Dr Etienne Maquet, Marloeke Bol, Françoise Lebrun-Klauser, Katie Thomson, Florence Rabier, Mireille Vosdey and Dr Véronique Fassnacht. Feeling sick at CERN has never been so nice. The medical service has been completely renewed over the last few months, and its team starts 2002 with fresh installations in order to make your state of indisposition less uncomfortable. Those who last visited building 57 six months ago probably won't recognise its new structure. Apart from a creamy colour on the wall, which cheers up the atmosphere, the distribution of the service has completely changed. You may find - as usual - the infirmary downstairs but the laboratory, the secretariat and the doctors on the first floor. Another main change is the reception in both ground floor (emergencies) and first floor. While you wait to be attended to, you can sit in a comfortable waiting room. The faces you'll find won't be familiar either: the nurses Ka...

  7. Medical Service: 40 years of outpatient care

    CERN Multimedia

    2005-01-01

    On 1st June 2005 the Medical Service will be celebrating its fortieth birthday. This will mark forty years of service to the health of CERN's personnel by the Medical Service's small team of doctors, nurses, laboratory assistants and secretaries. Since 1965, 27 280 medical files have been archived and computerised. The Medical Service. From left to right, front row : Mireille Vosdey, Marloeke Bol and Nicole De Matos. From left to right, back row : Katie Warrilow-Thomson, Dr Eric Reymond, Dr Véronique Fassnacht, Isabelle Auvigne and Françoise Lebrun-Klauser. The Medical Service was founded on 1st June 1965, with a staff of four: the doctor, Jean-Paul Diss, a nurse, a laboratory assistant and a secretary. Previously, a private medical practitioner had come to CERN to perform the medical check-ups on the personnel and the Fire Brigade was responsible for first aid. However, in view of increasing staff numbers and the specific needs of a Laboratory like CERN, an on-site Medical Service had become ess...

  8. Morgenthau: ¿el Maquiavelo de la política internacional?

    Directory of Open Access Journals (Sweden)

    Leonardo Carvajal H.

    2007-11-01

    Full Text Available Maquiavelo y Morgenthau respondieron con creces a la pregunta central: ¿en qué se diferencia la política internacional de las relaciones internacionales? Este interrogante fue considerado en las obras principales de los dos autores (El príncipe y Política entre las naciones, quienes establecen que los conceptos se diferencian en que el poder es el elemento esencial tanto en la política doméstica como en la “política internacional”; mientras que por “relaciones internacionales” se entiende todo el cúmulo de asuntos que tiene lugar en el escenario mundial, varios de los cuales no presentan ningún componente de “poder político” y, además, tales acciones se adelantan no sólo por parte del Estado sino también por una multiplicidad de actores que incluye individuos, iglesias, ONG, partidos, empresas. Es, pues, una interesante comparación entre el pensamiento de Nicolás Maquiavelo y el de Hans Morgenthau.

  9. $\\beta$-delayed neutrons from oriented $^{137,139}$I and $^{87,89}$Br nuclei

    CERN Document Server

    Grzywacz, Robert; Stone, Nicholas; Köster, Ulli; Singh, Barlaj; Bingham, Carrol; Gaulard, S; Kolos, Karolina; Madurga, Miguel; Nikolov, J; Otsubo, T; Roccia, S; Veskovic, Miroslav; Walker, Phil; Walters, William

    2013-01-01

    We propose a world-­‐first measurement of the angular distribution of $\\beta$-­‐delayed n and $\\gamma$- radiation from oriented $^{137, 139}$I and $^{87,89}$Br nuclei, polarised at low temperature at the NICOLE facility. $\\beta$-­‐delayed neutron emission is an increasingly important decay mechanism as the drip line is approached and its detailed understanding is essential to phenomena as fundamental as the r‐process and practical as the safe operation of nuclear power reactors. The experiments offer sensitive tests of theoretical input concerning the allowed and first-­‐forbidden $\\beta$‐decay strength, the spin-­‐density of neutron emitting states and the partial wave barrier penetration as a function of nuclear deformation. In $^{137}$I and $^{87}$Br the decay feeds predominantly the ground state of the daughters $^{136}$Xe and $^{86}$Kr whereas in $^{139}$I and $^{89}$Br we will explore the use of n-$\\gamma$- coincidence to study neutron transitions to the first and second excited state...

  10. Application of arbuscular mycorrhizal fungi on the production of cut flower roses under commercial-like conditions

    Energy Technology Data Exchange (ETDEWEB)

    Garmendia, I.; Mangas, V. J.

    2012-11-01

    The objective of this work was to study the influence of two arbuscular mycorrhizal fungi (AMF) Glomus mosseae (Nicol. and Gerd.) Gerd. and Trappe, and G. intraradices (Schenck and Smith) on cut flower yield of rose (Rosa hybrida L. cv. Grand Gala) under commercial-like greenhouse conditions. Flower production was positively influenced by G. mosseae inoculation. Both inocula tested caused low levels of mycorrhizal root colonization, with higher percentages in Rosa associated with G. mosseae. Significant improvement of plant biomass, leaf nutritional status or flower quality was not detected in inoculated plants probably due to the low symbiosis establishment. However, G. mosseae reduced by one month the time needed for 80% of the plants to flower and slightly increased number of cut flowers relative to non-mycorrhizal controls on the fourth, sixth and eighth months after transplanting. It is suggested that an altered carbohydrate metabolism could contribute to this positive effect. Low colonization of rose roots supports the idea that more effort is required to ensure successful application of AMF in ornamental production systems. (Author) 40 refs.

  11. Subjetividades emergentes en el manual de convivencia de la IED Nicolás Buenaventura y el Colegio Liceo Homérico

    OpenAIRE

    Gaviria De Lima, Christian Alan; Rojas Cordero, William

    2017-01-01

    Si bien las instituciones educativas ya sean de carácter oficial o privado poseen la autonomía para construir sus Manuales de Convivencia, los mismos deben tener en cuenta las disposiciones que el Ministerio de Educación Nacional refiere al respecto. Se hace evidente la puesta en escena de Manuales de Convivencia que no responden al contexto que viven los establecimientos, sin embargo, si tienen un efecto sobre la configuración del individuo. Los Manuales de Convivencia transportan un saber, ...

  12. Índice de qualidade em um latossolo amarelo coeso cultivado com citros Quality index in a cohesive yellow latosol cultivated with citrus

    Directory of Open Access Journals (Sweden)

    José Fernandes de Melo Filho

    2009-12-01

    Full Text Available O Brasil é o maior produtor mundial de citros e exportador de suco concentrado de laranja. Na região Nordeste, a citricultura tem grande importância social, onde é cultivada predominantemente por produtores com áreas menores do que 10 hectares, em solos como caráter coeso. Na Bahia, a citricultura é explorada sobre diversas condições tecnológicas, e especialmente nos Tabuleiros Costeiros os pomares têm baixa longevidade e produtividade em função das limitações dos solos coesos à produção agrícola. Este trabalho tem como objetivo determinar a qualidade física e química de um Latossolo Amarelo Coeso cultivado com citros. O estudo foi realizado na região do Recôncavo Baiano, em um pomar comercial de laranja "Pera" (Citrus sinensis L. Osb. sob porta-enxerto de limão-cravo (Citrus limonia L. Osb.. Para a determinação do índice de qualidade do solo (IQS, utilizou-se o método proposto por Karlen & Stott (1994, e amostras foram coletadas em duas camadas: 0,00 - 0,20 m e 0,20 - 0,40 m. Os resultados mostraram que o Latossolo Amarelo Coeso sob manejo tradicional para a cultura de citros apresentou índice de qualidade regular, com limitações determinadas pela elevada resistência do solo à penetração, baixa permeabilidade à água e baixo teor de matéria orgânica, o que resulta em limitações para permitir o crescimento e o aprofundamento do sistema radicular e prover o fornecimento e a disponibilidade de água para as plantas cítricas.Brazil is the greatest citrus producer and exporter of concentrated orange juice in the world. In the Northeast, the citriculture has a large social importance for farming family, which is predominantly cultivated for small farmers. In Bahia state the citriculture has been exploited under several technology conditions and especially in the Costal table lands soil the orchards have low longevity and productivity based on the cohesive soil limitations for rural production. The purpose of

  13. No evidence for a deglacial intermediate water Δ14C anomaly in the SW Atlantic

    Science.gov (United States)

    Sortor, R. N.; Lund, D. C.

    2010-12-01

    Reconstructions of Δ14C from the eastern tropical Pacific show that severe depletions in 14C occurred at intermediate depths during the last deglaciation (Marchitto et al. 2007; Stott et al. 2009). Marchitto et al. (2007) suggested that old radiocarbon from an isolated abyssal reservoir was injected via the Southern Ocean, and that this anomaly was then carried by Antarctic Intermediate Water (AAIW) to the tropical Pacific. However, a core from the southeastern Pacific Ocean near Chile, which is in the direct path of modern-day AAIW, does not exhibit the excursion and therefore casts doubts upon the AAIW mechanism (De Pol-Holz et al. 2010). Here we evaluate whether or not a deglacial 14C anomaly similar to that in the eastern tropical Pacific occurred at intermediate depths in the South Atlantic. We reconstructed Δ14C using planktonic and benthic foraminifera from core KNR159-5-36GGC on the Brazil Margin (27○31’S and 46○28’W, 1268 m depth). In the modern ocean, the hydrography near this core site is heavily influenced by AAIW (Oppo & Horowitz, 2000). Benthic Δ14C values were determined using raw benthic 14C ages and calendar-calibrated planktonic ages. The deglacial benthic Δ14C trend at this site is similar to the atmospheric Δ14C trend, and is consistent with U/Th-dated corals from intermediate depths on the Brazil Margin (Mangini et al. 2010). The amplitude and timing of Δ14C changes in the foraminiferal and coral records are especially congruous during the Mystery Interval. We find no evidence in the southwestern Atlantic of a ~300‰ decrease in intermediate water Δ14C beginning at 18 kyr BP. Changes in reservoir age of ~1000 years are required to create a Baja-like Δ14C anomaly off Brazil, an implausible increase for a subtropical gyre location. Furthermore, the resulting sedimentation rates would be up to ~145 cm/kyr during the deglaciation, an order of magnitude higher than the average sedimentation rate for 36GGC. When our results are

  14. Una canción inédita de Salomón Usque

    Directory of Open Access Journals (Sweden)

    Canals Piñas, Jordi

    2004-06-01

    Full Text Available Salomón Usque was descendant of Portuguese Jews that reached Ferrara during the Diaspora. He was possibly the son of Abraham Usque typographer of the Ferrara Bible (1553 written in ladino. We have evidence of his passing through Venice between 1560 and 1567, alternating stays in Constantinople, the Ottoman capital where he probably died. We owe to Salomón Usque the translation of Petrarch's Canzoniere into Spanish, published by Nicolò Bevilacqua in Venice in 1567. Usque is the author of the tragedy titled L’Ester arranged in 1619 by Leone Modena. He also wrote poetry in Italian. Among the manuscripts of the Ferrarían codex N.A. 5 belonging to the Biblioteca Ariostea there is a laudatory canzone addressed to Guidobaldo II Montefeltro (1514-1574, the Duke of Urbino, which is edited for the first time in the present article. The distribution of encyclopedic content reminds the distant source of St. Isidore of Seville, but there are some analogies with the poem Las siete edades del mundo written by Pablo de Santa Maria (born around 1350- 1435, a Spaniard converted Jew.

    Salomón Usque era hijo de judíos portugueses que la diáspora llevó a Ferrara. Fue tal vez hijo de Abraham Usque, tipógrafo de la Biblia de Ferrara en ladino (1553. Documentamos su paso por Venecia entre 1560 y 1567, alternando con estancias en Constantinopla, la capital otomana en la que probablemente murió. En 1567, el tipógrafo Nicolò Bevilacqua publicó en Venecia su traducción al castellano de la primera parte del Canzoniere de Petrarca. Fue autor de la tragedia L’Ester, refundida por Leone Modena en 1619. Compuso asimismo poesías en lengua italiana. Entre estas últimas registramos una canción encomiástica dirigida a Guidobaldo II Montefeltro (1514-1574, duque de Urbino, incluida en el códice manuscrito N.A. 5 de la Biblioteca Ariostea de Ferrara y que se edita aquí por vez primera

  15. La identidad nacional y Calderón en la polémica teatral de 1762-1764

    Directory of Open Access Journals (Sweden)

    Bezhanova, Olga

    2004-06-01

    Full Text Available Drawing on contemporary theories about national identity, legitimacy and intellectual authority this article explores identitarian issues at stake during the 1762-1764 controversy on Spanish theater. Re-reading texts by Clavijo y Fajardo (El Pensador, Nicolás Fernández de Moratín (Desengaños al teatro español and other writings, Mariano José Nipho (Diario Estrangero and La nación española defendida and José Romea y Tapia (El escritor sin título we contend that what these authors are debating indeed is not theater but the legitimacy and authority they are claiming for, and ultimately opposing conceptions of national identity. Calderón becoming a cultural icon of such identity. Particularly significant is the role of autos sacramentales in this context. In effect, acrimony and irritation are part of this polemics because orthodox Catholicism is, from a conservative point of view, an essential component of what they consider Spanish national identity. The prohibition of the autos is just a sign of a temporary change in the relationship of forces.A partir de teorías actuales sobre la identidad nacional, la legitimidad y la autoridad intelectual, este artículo explora los puntos clave identitarios que se ponen en juego durante la polémica sobre el teatro español de los años 1762-1764. Mediante una re-lectura de los textos de Clavijo y Fajardo (El Pensador, Nicolás Fernández de Moratín (Desengaños al teatro español y otros escritos, Mariano José Nipho (Diario Estrangero y La nación española defendida y José Romea y Tapia (El escritor sin título, sostenemos que lo que estos autores discuten realmente no es sobre el teatro, sino sobre la legitimidad y autoridad que reclaman, y en último término concepciones enfrentadas sobre la identidad nacional, de la que Calderón parece convertirse en icono cultural. De particular significación es el papel de los autos sacramentales en este contexto. En efecto, la acritud y la irritaci

  16. Percepción de la función de sus familias por adolescentes de la enseñanza media superior Preuniversity adolescents' perception of the functioning of their families

    Directory of Open Access Journals (Sweden)

    Daniel León Sánchez

    2008-09-01

    Full Text Available INTRODUCCIÓN. La disfunción familiar es un factor importante que condiciona la aparición de problemas socioculturales y de salud del adolescente, como la fármaco-dependencia, el embarazo, las enfermedades de transmisión sexual, la deserción escolar, la depresión y el suicidio. Esta investigación se realizó con el objetivo de valorar la percepción que tienen los adolescentes del funcionamiento de sus familias. MÉTODOS. Se realizó un estudio descriptivo en el que se seleccionaron a todos los adolescentes de 15 a 19 años que cursaron el nivel medio superior en el ciclo escolar 2001-2002 en la escuela preuniversitaria núm. 1 del "Colegio Primitivo y Nacional de San Nicolás de Hidalgo", Michoacán (México. Se efectuó una encuesta anónima a los adolescentes que decidieron participar y estos evaluaron el funcionamiento de sus respectivas familias mediante el Apgar familiar. RESULTADOS. Se encontró disfunción familiar asociada a nivel educacional alto en los padres (p INTRODUCTION: Family dysfunction is a significant factor conditioning the appearance of sociocultural and health problems in adolescents, such as drug dependence, pregnancy, sexually transmitted diseases, school desertion, depressison, and suicide. The aim of this research was to assess how adolescents perceive the functioning of their families. METHODS: A descriptive study that included all the adolescents aged 15-19 that were studying in No. 1 preuniversitary school of " Colegio Primitivo and Nacional of San Nicolás de Hidalgo", Michoacán, Mexico, from 2001 to 2002, was conducted. An anonymous survey was done among the adolescents that decided to take part and they assessed the functioning of their respective families by means of the family Apgar. RESULTS: A family dysfunction associated with high educational level in parents (p <0.005, phi = 0.241, with the occupational status of their parents (p < 0.001, phi = 0.775, with a great frequency of addiction in

  17. Valorar la factibilidad del modelo teórico de selección de Futuros Talentos en el municipio San Nicolás

    OpenAIRE

    Irina Rodríguez Oviedo

    2009-01-01

    Perfeccionar hasta optimizar, los métodos científicos de selección y desarrollo de niños para la práctica deportiva es un problema de interés relevante en el ámbito internacional y una necesidad pedagógica, política y económica del país. Fortalecer el proceso de selección en el voleibol  es  la mayor ambición en la que se ha enmarcado esta investigación a través de     la elaboración de un modelo  de  selección  de  futuros  talentos  del  voleibol  infantil  edades  (7-  8). Históricamente e...

  18. Cinco proyectos del arquitecto Nicolás de Morales para los planes de repoblación de la provincia de Extremadura (1779

    Directory of Open Access Journals (Sweden)

    Justina Rodríguez García

    1990-01-01

    Full Text Available En la primavera de 1778, don Pedro Rodríguez Campomanes realizó un viaje por la provincia de Extremadura, cuyas impresiones y observaciones recogió en una amplia memoria que presentó al Consejo con el fin de informar a dicho organismo de la situación y estado de estas apartadas tierras.

  19. Valorar la factibilidad del modelo teórico de selección de Futuros Talentos en el municipio San Nicolás

    Directory of Open Access Journals (Sweden)

    Irina Rodríguez Oviedo

    2009-03-01

    Full Text Available Perfeccionar hasta optimizar, los métodos científicos de selección y desarrollo de niños para la práctica deportiva es un problema de interés relevante en el ámbito internacional y una necesidad pedagógica, política y económica del país. Fortalecer el proceso de selección en el voleibol  es  la mayor ambición en la que se ha enmarcado esta investigación a través de     la elaboración de un modelo  de  selección  de  futuros  talentos  del  voleibol  infantil  edades  (7-  8. Históricamente el “Proceso de Selección” en la categoría de iniciación se realiza utilizando con un único   indicador (estatura avalado por los conocimientos de los  entrenadores de la  base.  Este  modelo  constituye  el  comienzo  del  largo proceso de selección, a la vez se convierte en una herramienta para el control y evaluación  individual y colectivo del proceso de enseñanza y entrenamiento en la categoría de iniciación; instrumento para los entrenadores del eslabón base, el cual se debe  aplicar a todos los sujetos que se encuentran en este rango de edades para prevenir la perdida de niño con potencialidades para práctica del voleibol.El objetivo del modelo es lograr homogeneizar y  masificar la selección desde la categoría de iniciación, contemplando el desarrollo de las capacidades según las  fases sensibles en función de las exigencias de este deporte en este grupo etáreo. Utilizando los criterios e indicadores propuestos que actúen como un sistema.

  20. Unusual past dry and wet rainy seasons over Southern Africa and South America from a climate perspective

    Directory of Open Access Journals (Sweden)

    Omar Bellprat

    2015-09-01

    Full Text Available Southern Africa and Southern South America have experienced recent extremes in dry and wet rainy seasons which have caused severe socio-economic damages. Selected past extreme events are here studied, to estimate how human activity has changed the risk of the occurrence of such events, by applying an event attribution approach (Stott et al., 2004comprising global climate models of Coupled Model Intercomparison Project 5 (CMIP5. Our assessment shows that models' representation of mean precipitation variability over Southern South America is not adequate to make a robust attribution statement about seasonal rainfall extremes in this region. Over Southern Africa, we show that unusually dry austral summers as occurred during 2002/2003 have become more likely, whereas unusually wet austral summers like that of 1999/2000 have become less likely due to anthropogenic climate change. There is some tentative evidence that the risk of extreme high 5-day precipitation totals (as observed in 1999/2000 have increased in the region. These results are consistent with CMIP5 models projecting a general drying trend over SAF during December–January–February (DJF but also an increase in atmospheric moisture availability to feed heavy rainfall events when they do occur. Bootstrapping the confidence intervals of the fraction of attributable risk has demonstrated estimates of attributable risk are very uncertain, if the events are very rare. The study highlights some of the challenges in making an event attribution study for precipitation using seasonal precipitation and extreme 5-day precipitation totals and considering natural drivers such as ENSO in coupled ocean–atmosphere models.

  1. Temperatura y rangos de confort térmico en viviendas de bajo costo en clima árido seco

    Directory of Open Access Journals (Sweden)

    Luis Herrera Sosa

    2013-06-01

    Full Text Available Este documento presenta los resultados de un estudio de campo para determinar la temperatura de confort de habitantes de viviendas de bajo costo en dos ciudades de clima cálido-seco al norte de México: Chihuahua (28º LN, 106º LO y Ciudad Juárez (31ºLN, 106ºLO. El estudio de campo se realizó con el enfoque adaptativo de confort térmico y de acuerdo con los requerimientos de la ISO 10551. El estudio fue aplicado a 531 habitantes de viviendas construidas por el Instituto de Vivienda de Chihuahua, durante dos periodos: temporada de invierno (febrero y temporada de verano (julio. Como el clima de la región tiene características de climas "asimétricos", llamado así por Nicol (1993, los datos obtenidos en el estudio de campo se analizaron mediante el Método Intervalos de los Promedios de Sensación Térmica (IPST (Gómez-Azpeitia, et. al, 2009. La investigación tiene como objetivos evaluar este tipo de viviendas que ofrece el gobierno local y proponer recomendaciones para el diseño de nuevas viviendas.

  2. Improving clinical leadership and management in the NHS

    Directory of Open Access Journals (Sweden)

    Nicol ED

    2012-08-01

    Full Text Available Edward D Nicol1,21Department of Cardiology, Royal Brompton Hospital and Harefield NHS Trust, London, United Kingdom; 2Clinical Leadership Academy, School of Medicine, Keele University, Staffordshire, United KingdomAbstract: The National Health Service (NHS is one of the UKs most cherished but political public institutions, providing healthcare, free at the point of delivery. The English NHS must make £20bn efficiency savings in the next 3 years whilst in the midst of fundamental structural change outlined in the government's Health and Social Care Bill. This paper will explore the history of leadership and management in the NHS; the evolution of clinical leadership; national strategies to improve NHS clinical and managerial leadership and Lord Darzi's pivotal NHS review. It defines the kind of leadership and management required for today's NHS, looking to overcome some of the main challenges such as improving healthcare quality whilst making efficiency savings and engaging grass roots workers to deliver sustainable, long term improvements. Finally this manuscript makes suggestions as to where future investment is required to improve clinical leadership and management in the NHS.Keywords: clinical leadership, healthcare management, national health service

  3. MAGNETIC FLUX CANCELLATION IN ELLERMAN BOMBS

    Energy Technology Data Exchange (ETDEWEB)

    Reid, A.; Mathioudakis, M.; Nelson, C. J.; Henriques, V. [Astrophysics Research Centre, School of Mathematics and Physics, Queen’s University Belfast, BT7 1NN, Northern Ireland (United Kingdom); Doyle, J. G. [Armagh Observatory, College Hill, Armagh, BT61 9DG (United Kingdom); Scullion, E. [Trinity College Dublin, College Green, Dublin 2 (Ireland); Ray, T., E-mail: areid29@qub.ac.uk [Dublin Institute for Advanced Studies, 31 Fitzwilliam Place, Dublin 2 (Ireland)

    2016-06-01

    Ellerman Bombs (EBs) are often found to be co-spatial with bipolar photospheric magnetic fields. We use H α imaging spectroscopy along with Fe i 6302.5 Å spectropolarimetry from the Swedish 1 m Solar Telescope (SST), combined with data from the Solar Dynamic Observatory , to study EBs and the evolution of the local magnetic fields at EB locations. EBs are found via an EB detection and tracking algorithm. Using NICOLE inversions of the spectropolarimetric data, we find that, on average, (3.43 ± 0.49) × 10{sup 24} erg of stored magnetic energy disappears from the bipolar region during EB burning. The inversions also show flux cancellation rates of 10{sup 14}–10{sup 15} Mx s{sup −1} and temperature enhancements of 200 K at the detection footpoints. We investigate the near-simultaneous flaring of EBs due to co-temporal flux emergence from a sunspot, which shows a decrease in transverse velocity when interacting with an existing, stationary area of opposite polarity magnetic flux, resulting in the formation of the EBs. We also show that these EBs can be fueled further by additional, faster moving, negative magnetic flux regions.

  4. Bridging gaps in discovery and development: chemical and biological sciences for affordable health, wellness and sustainability.

    Science.gov (United States)

    Chauhan, Prem Man Singh

    2011-05-01

    To commemorate 2011 as the International Year of Chemistry, the Indian Society of Chemists and Biologists organized its 15th International Conference on 'Bridging Gaps in Discovery and Development: Chemical and Biological Sciences for Affordable Health, Wellness and Sustainability' at Hotel Grand Bhagwati, in association with Saurashtra University, Rajkot, India. Anamik Shah, President of the Indian Society of Chemists and Biologists, was organizing secretary of the conference. Nicole Moreau, President of the International Union of Pure and Applied Chemistry and Secretary General of the Comité National de la Chimie, National Centre for Scientific Research France, was chief guest of the function. The four-day scientific program included 52 plenary lectures, 24 invited lectures by eminent scientists in the field and 12 oral presentations. A total of 317 posters were presented by young scientists and PhD students in three different poster sessions. Approximately 750 delegates from India, the USA, UK, France, Switzerland, Germany, Austria, Belgium, Sweden, Japan and other countries attended the conference. The majority of the speakers gave presentations related to their current projects and areas of interest and many of the talks covered synthesis, structure-activity relationships, current trends in medicinal chemistry and drug research.

  5. Tránsito a la “modernidad”: crisis, turismo, administración, evolución e hibridez

    Directory of Open Access Journals (Sweden)

    Rita María Trujillo González

    2016-01-01

    Full Text Available En La Aldea de San Nicolás, localidad situada en el oeste de Gran Canaria, la actual crisis tomatera ha provocado la búsqueda de alternativas económicas y complementarias a la agricultura. Una posibilidad que ha cobrado relevancia en los últimos años, es el otorgamiento de un mayor protagonismo al “turismo rural”. En este artículo me propongo plantear las dificultades a las que ha de hacer frente esta opción, como es el desacuerdo existente entre los vecinos ante una mayor implantación turística, al hacer un uso diferenciado de conceptos relevantes en la temática turística, tales como “identidad”, “cultura”, “valor” o “tradición”, que pueden abarcar contenidos más “esencialistas” o más “constructivistas”. Por otra parte, planteo la posibilidad de observar el proceso administrativo como una situación de tránsito propia de las sociedades contemporáneas, con características análogas al rito de paso, que modifican la realidad a nivel macro y micro etnográfico.

  6. Novel pharmacologic treatment in acute binge eating disorder – role of lisdexamfetamine

    Directory of Open Access Journals (Sweden)

    Guerdjikova AI

    2016-04-01

    Full Text Available Anna I Guerdjikova,1,2 Nicole Mori,1,2 Leah S Casuto,1,2 Susan L McElroy1,2 1Lindner Center of HOPE, Mason, OH, USA; 2Department of Psychiatry and Behavioral Neuroscience, University of Cincinnati College of Medicine, Cincinnati, OH, USA Abstract: Binge eating disorder (BED is the most common eating disorder and an important public health problem. It is characterized by recurrent episodes of excessive food consumption accompanied by a sense of loss of control over the binge eating behavior without the inappropriate compensatory weight loss behaviors of bulimia nervosa. BED affects both sexes and all age groups and is associated with medical and psychiatric comorbidities. Until recently, self-help and psychotherapy were the primary treatment options for patients with BED. In early 2015, lisdexamfetamine dimesylate, a prodrug stimulant marketed for attention deficit hyperactive disorder, was the first pharmacologic agent to be approved by the US Food and Drug Administration for the treatment of moderate or severe BED in adults. This article summarizes BED clinical presentation, and discusses the pharmacokinetic profile, efficacy, and safety of lisdexamfetamine dimesylate in the treatment of BED in adults. Keywords: binging, overeating, Vyvanse, stimulant, approved medication

  7. Media coverage of celebrity DUIs: teachable moments or problematic social modeling?

    Science.gov (United States)

    Smith, Katherine Clegg; Twum, Denise; Gielen, Andrea Carlson

    2009-01-01

    Alcohol in the media influences norms around use, particularly for young people. A recent spate of celebrity arrests for drinking and driving (DUI) has received considerable media attention. We asked whether these newsworthy events serve as teachable moments or problematic social modeling for young women. Qualitative analysis of US media coverage of four female celebrities (Michelle Rodriguez, Paris Hilton, Nicole Richie and Lindsay Lohan) was conducted over the year following their DUI arrest (December 2005 through June 2008). The media sample included five television and three print sources and resulted in 150 print and 16 television stories. Stories were brief, episodic and focused around glamorous celebrity images. They included routine discussion of the consequences of the DUI for the individual celebrities without much evidence of a consideration of the public health dimensions of drinking and driving or possible prevention measures. Our analysis found little material in the media coverage that dealt with preventing injury or promoting individual and collective responsibility for ensuring such protection. Media attention to such newsworthy events is a missed opportunity that can and should be addressed through media advocacy efforts.

  8. The Exclusion of Liability for Emotional Harm to Passengers in the Warsaw and Montréal Convention: Moving Away from Floyd, Siddhu and Pienaar to the Stott Case?

    Directory of Open Access Journals (Sweden)

    Rafia De Gama

    2017-01-01

    Full Text Available This contribution focuses on the transport of passengers on international routes and the legal regime set down by the Warsaw Convention of 1929 and reinforced by the Montréal Convention of 1999. These Conventions regulate commercial aviation by detailing a set of minimum standardised procedures for flight safety, such as standards for air navigation systems, amongst others, to ensure safe and efficient air travel. The legal regime also regulates the possible claims that may be made against airlines for the death of or harm to passengers, as well as relating to damage to and loss of baggage. The regime not only limits claims temporally and by location, but it also excludes the application of national legal regimes. With regard to claims of harm to dignity the regime disallows such claims to be brought within the restrictions placed by the legal regimes or on any other basis. The contribution does not address the full coverage of these Conventions, only the exclusion of mental / emotional injuries. The Convention excludes emotional harm from the definition of death and physical harm. However claimants have brought claims to undermine the main exclusion of claims with regard to compensation for emotional harm. This contribution explores the exclusion of claims in the Warsaw and Montréal Conventions and thereafter analyses two court decisions in common law countries where this exclusion of claims was challenged and the challenge failed.

  9. La Familia Esguerra en la Historia de Colombia

    Directory of Open Access Journals (Sweden)

    José Francisco Socarrás

    1992-03-01

    , las fiebres del Alto Magdalena. Y continúa con el escritor y abogado Arsenio Esguerra, publicista y geógrafo, Joaquín Esguerra y Manuel Esguerra, diplomático, y para finalizar, “el tercer Domingo de la casa”.

    El doctor López se refiere en particular a don Nicolás Esguerra Ortiz, de quien hace merecido elogio. Ignoro si la Familia Esguerra posee una genealogía de apellido tan importante en la historia de Colombia. Lo dudo, porque la materia en nuestro país sólo ha sido motivo de estudios detallados en los Departamentos de Antioquia y Caldas.

    I

    Bien vale la pena detenerse así sea a grandes rasgos en la vida de don Nicolás Esguerra, quien fuera figura deslumbrante en nuestro siglo XIX, para lo cual seguiré a la letra los datos biográficos que del ilustre hombre público nos legaron don Edmundo Rodríguez Piñeres en su obra “El Olimpo Radical” y don Luis De Greiff Obregón en “Semblanzas y Comentarios”.

    El doctor Nicolás Esguerra nació el 10 de septiembre de 1838 y murió el 23 de diciembre de 1923. ¿Padres del notable patricio? El coronel Domingo Esguerra y la tolimense doña Serafina Ortiz Fernández. Sus años de infancia transcurrieron en Ibagué, por lo cual inició estudios en el Colegio de San Simón. Enviado por sus padres a Bogotá, continuó el bachillerato en el Colegio de San Bartolomé, donde permaneció hasta la expulsión de los Jesuítas en 1851. Volvió a San Simón y allí terminó la enseñanza secundaria. Regresó a Bogotá donde vivió en la casa del doctor Manuel Murillo Toro, alojamiento ofrecido por el gran colombiano a los padres del joven estudiante. Este se matriculó en el Colegio Mayor de Nuestra Señora del Rosario, donde cursó filosofía, derecho y ciencias políticas. Recibió el doctorado en 1858 cuando apenas tenía 20 años.

    Adolescente todavía fue nombrado juez en una población del Departamento del Tolima y su primer acto fue poner en libertad a numerosos presos, mantenidos

  10. Auge y declive de la reforma socialista en la Universidad Michoacana, 1926-1940

    Directory of Open Access Journals (Sweden)

    Miguel Angel Gutiérrez López

    2015-02-01

    Full Text Available Las primeras décadas del siglo XX son consideradas años de reformas universitarias en América Latina. Los universitarios tuvieron una activa participación política y una militancia ideológica que los llevó muchas veces a la radicalización. En la Universidad Michoacana de San Nicolás de Hidalgo, una de las más antiguas de México y la primera autónoma, el liderazgo y el control político lo asumieron grupos identificados con los sectores revolucionarios de izquierda. En los años veinte y treinta, un importante sector de universitarios michoacanos asumió el control de su institución con el objetivo de imprimirle una orientación socialista y apoyar el programa político que desde el poder impulsaba Lázaro Cárdenas. En el texto se aborda el proceso de creación y reacomodo de las fuerzas y organizaciones estudiantiles en la Universidad Michoacana en los años veinte y treinta. El escenario es el de la educación socialista y el de los intentos de las autoridades universitarias por controlar política e ideológicamente al estudiantado organizado. Además, el artículo hace referencia a la consolidación y vigencia del liderazgo socialista. El movimiento socialista de reforma universitaria funcionó como una escuela ideológica de la que emergieron varios líderes estudiantiles que en poco tiempo ocuparon posiciones destacadas en el ámbito político nacional.      The first decades of the twentieth century are thought of as years of university reforms in Latin America. Alumni at universities were politically active and ideologically militant, which oftentimes led to radicalization. Groups that identified with revolutionary leftist groups assumed leadership and political control of the Universidad Michoacana de San Nicolás de Hidalgo, which is one of the oldest in Mexico and the first to become autonomous. During the twenties and thirties, a significant portion of the students seized control of the institution in order to imprint

  11. Crescimento de mudas de maracujazeiro-doce (Passiflora alata Curtis associadas a fungos micorrízicos arbusculares (Glomeromycota Growth of seedlings of sweet-passion fruit (Passiflora alata Curtis associated to arbuscular mycorrhizal fungi (Glomeromycota

    Directory of Open Access Journals (Sweden)

    Maryluce Albuquerque da Silva

    2004-12-01

    Full Text Available Para determinar o efeito de fungos micorrízicos arbusculares sobre o crescimento de mudas de maracujazeiro-doce foi conduzido, em casa de vegetação, experimento com delineamento inteiramente casualizado usando cinco tratamentos de inoculação (200 esporos/planta de Acaulospora longula Spain & Schenck, Gigaspora albida Schenck & Smith, Glomus etunicatum Becker & Gerd., Scutellospora heterogama (Nicol. & Gerd. Walker & Sanders e controle não inoculado, com sete repetições. A cada 20 dias foram avaliados altura e número de folhas e ao final do experimento (90 dias: diâmetro do caule, biomassa, área foliar, colonização micorrízica e densidade de esporos de FMA na rizosfera. A partir de 70 dias foram evidenciadas diferenças no número de folhas; aos 90 dias as plantas inoculadas com G. albida apresentaram maior altura que as demais, que não diferiram significativamente entre si. Plantas associadas com esse fungo apresentaram, em relação ao controle, incrementos de 2.138% e 1.430% nas biomassas fresca e seca da parte aérea, 1.937% na biomassa fresca da raiz e 2.671% na área foliar. Apesar de não existir especificidade de hospedeiro na associação micorrízica arbuscular, apenas G. albida promoveu respostas significativas no maracujazeiro-doce, indicando a existência de maior compatibilidade funcional entre esses simbiontes.In order to determine the effect of arbuscular mycorrhizal fungi (AMF on growth of seedlings of sweet-yellow passion fruit, a greenhouse experiment was performed, using 200 AMF spores/plant in a randomized design with five treatments of inoculation (Acaulospora longula Spain & Schenck, Gigaspora albida Schenck & Smith, Glomus etunicatum Becker & Gerd., Scutellospora heterogama (Nicol. & Gerd. Walker & Sanders, and a non inoculated control with seven replicates. Every 20 days height and leaf number and after 90 days shoot diameter, biomass, leaf area, root colonization and density of AMF spores in the

  12. Aspectos ecológicos de fungos micorrízicos vesículo-arbusculares da mata tropical úmida da Ilha do Cardoso, SP, Brasil Ecological aspects of mycorrhizal vesicular-arbuscular fungi of the tropical humid forest of Cardoso Island, SP, Brazil

    Directory of Open Access Journals (Sweden)

    Sandra F. B Trufem

    1990-12-01

    Full Text Available No período de agosto/1984 a maio/1987, em nove ocasiões, foram coletadas 300 amostras de solo da rizosfera de 35 espécies de plantas nativas da mata tropical úmida do Parque Estadual da Ilha do Cardoso, SP, Brasil, para a investigação da ocorrência de fungos micorrízicos vesículo-arbusculares (MVA ea obtenção de dados sobre aspectos ecológicos desses microrganismos. Foram verificados 35 taxa de fungos MV A, sete dos quais espécies novas. Os esporos qué ocorreram em maior quantidade foram os de Acaulospora foveata Trappe & Janos, Acaulospora scrobiculata Trappe, Glomus etunicatum Becker & Gerd.. Glomus geosporum (Nicol. & Gerd. Walker, Glomus macrocarpum Tul. & Tul. e Glomus microcarpum Tul. & Tul. As plantas cujas rizosferas apresentaram maior número de esporos de fungos MV A foram as de Blechnum serrulatum L.C. Rich., Euterpe edulis Mart, Neomarica caerulia Sprague, Geonoma elegans Mart, e Piper aduncum L. A maior diversidade de espécies de fugnos MV A ocorreu nas rizosferas de Aphettandra sp., Geonoma elegans Mart e Leandra barbinervis Cogn. Verificouse que houve predominancia de espécies de fungos micorrízicos vesículo-arbusculares clamidospóricas sobre as azigospóricas, bem como que a quantidade de esporos em urna dada rizosfera está diretamente relacionada com a diversidade. Glomus monosporum Gerd. & Trappe e as espécies de Sclerocystis podem ser apontadas como características do ecossistema estudado, que apresentou a média de 50,04 esporos/ 100g de solo.From August/1984 to May/1987, 300 soil samples were collected from the rhizospheres of 35 species of native plants of Parque Estadual da Ilha do Cardoso, SP, Brazil, in a wet tropical forest, to investigate the occurrence and some ecological aspects of vesicular-arbuscular mycorrhizal (VAM fungi. Thirty five taxa of VA M fungi were reported, seven of them as new species. The most numerous VA M fungal spores belong to Acaulospora foveata Trappe & Janos, Acaulospora

  13. Una mezquita de «nueve bóvedas» en Córdoba. Estudio arquitectónico de un edificio desaparecido en 1725

    Directory of Open Access Journals (Sweden)

    García-Ortega, Antonio Jesús

    2012-06-01

    Full Text Available After the Castilian conquest of Córdoba in 1236, a small mosque next to the Guadalquivir River was converted into the parish church of San Nicolás de la Ajerquía. The building was extended until the mid-sixteenth century and repeatedly transformed over time. However, the ancient Islamic building existed until its demolition during the important reforms of the period 1725-1727. There are several documentary records of those years, and also a plan sketch preserved in the parish archive. However, this mosque has gone virtually unnoticed by the specialized historiography, perhaps because the limited and ambiguous data hinder a proper valuation of its architectural form. In this study the original drawing has been analyzed, contextualizing it with several plans and historical documents. This has produced a hypothesis about the size of the mosque’s prayer hall, its approximate orientation, as well as its interior architectural organization: an almost square plan, subdivided into nine areas covered with vaults. Therefore, it could be framed within a type of mosque detected long ago by Creswell, who called it “ninedome- mosque”. The building would be the only known example of such architectural type in Córdoba.

    Tras la conquista castellana de Córdoba, en 1236, la nueva parroquia de San Nicolás de la Ajerquía aprovechó como iglesia una pequeña mezquita junto al río Guadalquivir. El edificio, ampliado a mitad del siglo XVI y reiteradamente transformado a lo largo del tiempo, mantuvo la preexistencia islámica hasta las importantes reformas del período 1725-27, que supusieron su total demolición. Pese a que existen varias alusiones documentales de aquellos años y un dibujo a mano alzada de la planta conservado en el archivo parroquial, esta mezquita ha pasado prácticamente inadvertida en la historiografía especializada, quizás porque los escasos y ambiguos datos conocidos no permiten estimar su arquitectura. En este trabajo se

  14. Ocorrência de Fungos Micorrízicos Arbusculares em resíduo da mineração de bauxita revegetado com espécies arbóreas Arbuscular mycorrhizal fungi occurrence in bauxite mining residue planted to tree species

    Directory of Open Access Journals (Sweden)

    Ana Lucy Caproni

    2007-03-01

    Full Text Available Avaliou-se a ocorrência de fungos micorrízicos arbusculares (FMAs em tanques contendo resíduo da mineração de bauxita cultivados com espécies arbóreas inoculadas com Glomus clarum Nicol. & Schenck e Gigaspora margarita Becker & Hall na fase de viveiro. Acacia holosericea A. Cunn. ex G. Don juntamente com Sesbania virgata (Cav. Pers. ou uma mistura de várias espécies foram transplantadas em tanques contendo resíduo de bauxita. Coletaram-se amostras de resíduos em agosto/1998 (estação seca e abril/1999 (estação chuvosa, extraíram e identificaram-se os esporos de FMAs. Determinaram-se a densidade dos esporos de FMAs, a densidade relativa, a freqüência de ocorrência de cada espécie por período de amostragem e o índice de abundância e freqüência (IAF. A densidade dos esporos e a diversidade das espécies de FMAs foram baixas sob ambas as coberturas. Um maior número de esporos de Glomus clarum, e alto IAF, foram detectados no substrato cultivado com Acacia holosericea e Sesbania virgata na época seca. Isto também ocorreu em ambas as áreas na época chuvosa. Não foram encontrados esporos de Gigaspora margarita em ambas as áreas, nas duas épocas. Independentemente da inoculação, verificaram-se esporos de Archeospora leptoticha (Schenck & Smith Morton & Redecker, Entrophospora colombiana Spain & Schenck, Acaulospora mellea Spain & Schenck e Glomus macrocarpum Tulasne & Tulasne em abundância.The establishment of arbuscular mycorrhizal fungi (AMF was evaluated in two areas of bauxite mining residue planted to tree species inoculated with Glomus clarum Nicol. & Schenck and Gigaspora margarita Becker & Hall in the nursery phase. Acacia holosericea A. Cunn. ex G. Don and Sesbania virgata (Cav. Pers. and a mixture of several tree species were transplanted to deposits of containing bauxite mining residue. In August, 1998 (dry season and April, 1999 (rainy season residue samples were collected and AMF spores extracted and

  15. Nutrition support and dietary interventions for patients with lung cancer: current insights

    Directory of Open Access Journals (Sweden)

    Kiss N

    2016-01-01

    Full Text Available Nicole Kiss1,2 1Nutrition and Speech Pathology Department, Peter MacCallum Cancer Centre, East Melbourne, VIC, Australia; 2Department of Cancer Experiences Research, Peter MacCallum Cancer Centre, East Melbourne, VIC, Australia Abstract: Malnutrition and weight loss are prevalent in patients with lung cancer. The impact of malnutrition on patients with cancer, and specifically in patients with lung cancer, has been demonstrated in a large number of studies. Malnutrition has been shown to negatively affect treatment completion, survival, quality of life, physical function, and health care costs. Emerging evidence is providing some insight into which lung cancer patients are at higher nutritional risk. In lung cancer patients treated with radiotherapy, stage III or more disease, treatment with concurrent chemotherapy and the extent of radiotherapy delivered to the esophagus appear to confer a higher risk of weight loss during and post-treatment. Studies investigating nutrition interventions for lung cancer patients have examined intensive dietary counseling, supplementation with fish oils, and interdisciplinary models of nutrition and exercise interventions and show promise for improved outcomes from these interventions. However, further research utilizing these interventions in large clinical trials is required to definitively establish effective interventions in this patient group. Keywords: lung cancer, nutrition, malnutrition

  16. La hora de la decisión. ¿Cómo logró “Merkozy” establecer las bases para una nueva Europa?

    Directory of Open Access Journals (Sweden)

    Andreas Rinke

    2011-11-01

    Full Text Available Los países de la zona euro vivieron durante 2011 algunos de los meses más dramáticos desde la creación del euro llegando transitoriamente a su fin con la política del eje franco-alemán que produjo un cambio en la arquitectura de la Unión Europea. El viejo debate sobre la “Europa de los círculos concéntricos” o de un “núcleo Europa” dejó de ser una teoría y se convirtió en realidad: el grupo de los 17 países de la eurozona se dio a partir de ese momento un nuevo marco. El presente texto señala, desde la óptica alemana, qué sucedió durante todos estos meses, reconstruye cómo cambió la posición de la canciller Angela Merkel ante la crisis económica, pasando de una actitud defensiva a una actitud ofensiva de respuesta, y muestra cómo finalmente esto llevó, con el apoyo decisivo del entonces mandatario francés Nicolás Sarkozy, a una transformación institucional importante al interior de la Unión Europea.

  17. VolcLab: A balloon-borne instrument package to measure ash, gas, electrical, and turbulence properties of volcanic plumes

    Science.gov (United States)

    Airey, Martin; Harrison, Giles; Nicoll, Keri; Williams, Paul; Marlton, Graeme

    2017-04-01

    user; it is essentially plug-and-play with commercial radiosondes enabling seamless integration with standard technology. It is cheap and disposable, having been designed with software at the heart of device operation, which controls basic electronic components. The single package allows several plume properties to be measured and transmitted simultaneously in real time. These systems can be deployed rapidly as part of a wider network of launches allowing spatially referenced datasets to be integrated with remotely sensed data. These measurements provide in situ plume characteristics for airspace risk management planning as well as providing valuable scientific information on plume dynamics. References [1] Safety and Airspace Reguation Group, Guidance regarding flight operations in the vicinity of volcanic ash, CAP 1236 (Third edition), 2014, Civil Aviation Authority. [2] Harrison, R.G. and Nicoll, K.A. (2014) Rev. Sci. Instrum., 85, 6, 3 [3] Nicoll, K.A. (2013) Rev. Sci. Instrum., 84, 9, 3 [4] Marlton, G.J., et al. (2015) Rev. Sci. Instrum., 86, 1 [5] Harrison, R.G., et al. (2012) Rev. Sci. Instrum., 83, 3

  18. Evolutionary thinking

    Science.gov (United States)

    Hunt, Tam

    2014-01-01

    Evolution as an idea has a lengthy history, even though the idea of evolution is generally associated with Darwin today. Rebecca Stott provides an engaging and thoughtful overview of this history of evolutionary thinking in her 2013 book, Darwin's Ghosts: The Secret History of Evolution. Since Darwin, the debate over evolution—both how it takes place and, in a long war of words with religiously-oriented thinkers, whether it takes place—has been sustained and heated. A growing share of this debate is now devoted to examining how evolutionary thinking affects areas outside of biology. How do our lives change when we recognize that all is in flux? What can we learn about life more generally if we study change instead of stasis? Carter Phipps’ book, Evolutionaries: Unlocking the Spiritual and Cultural Potential of Science's Greatest Idea, delves deep into this relatively new development. Phipps generally takes as a given the validity of the Modern Synthesis of evolutionary biology. His story takes us into, as the subtitle suggests, the spiritual and cultural implications of evolutionary thinking. Can religion and evolution be reconciled? Can evolutionary thinking lead to a new type of spirituality? Is our culture already being changed in ways that we don't realize by evolutionary thinking? These are all important questions and Phipps book is a great introduction to this discussion. Phipps is an author, journalist, and contributor to the emerging “integral” or “evolutionary” cultural movement that combines the insights of Integral Philosophy, evolutionary science, developmental psychology, and the social sciences. He has served as the Executive Editor of EnlightenNext magazine (no longer published) and more recently is the co-founder of the Institute for Cultural Evolution, a public policy think tank addressing the cultural roots of America's political challenges. What follows is an email interview with Phipps. PMID:26478766

  19. Impact of Drought on Groundwater and Soil Moisture - A Geospatial Tool for Water Resource Management

    Science.gov (United States)

    Ziolkowska, J. R.; Reyes, R.

    2016-12-01

    For many decades, recurring droughts in different regions in the US have been negatively impacting ecosystems and economic sectors. Oklahoma and Texas have been suffering from exceptional and extreme droughts in 2011-2014, with almost 95% of the state areas being affected (Drought Monitor, 2015). Accordingly, in 2011 alone, around 1.6 billion were lost in the agricultural sector alone as a result of drought in Oklahoma (Stotts 2011), and 7.6 billion in Texas agriculture (Fannin 2012). While surface water is among the instant indicators of drought conditions, it does not translate directly to groundwater resources that are the main source of irrigation water. Both surface water and groundwater are susceptible to drought, while groundwater depletion is a long-term process and might not show immediately. However, understanding groundwater availability is crucial for designing water management strategies and sustainable water use in the agricultural sector and other economic sectors. This paper presents an interactive geospatially weighted evaluation model and a tool at the same time to analyze groundwater resources that can be used for decision support in water management. The tool combines both groundwater and soil moisture changes in Oklahoma and Texas in 2003-2014, thus representing the most important indicators of agricultural and hydrological drought. The model allows for analyzing temporal and geospatial long-term drought at the county level. It can be expanded to other regions in the US and the world. The model has been validated with the Palmer Drought Index Severity Index to account for other indicators of meteorological drought. It can serve as a basis for an upcoming socio-economic and environmental analysis of drought events in the short and long-term in different geographic regions.

  20. Evolutionary thinking: "A conversation with Carter Phipps about the role of evolutionary thinking in modern culture".

    Science.gov (United States)

    Hunt, Tam

    2014-12-01

    Evolution as an idea has a lengthy history, even though the idea of evolution is generally associated with Darwin today. Rebecca Stott provides an engaging and thoughtful overview of this history of evolutionary thinking in her 2013 book, Darwin's Ghosts: The Secret History of Evolution. Since Darwin, the debate over evolution-both how it takes place and, in a long war of words with religiously-oriented thinkers, whether it takes place-has been sustained and heated. A growing share of this debate is now devoted to examining how evolutionary thinking affects areas outside of biology. How do our lives change when we recognize that all is in flux? What can we learn about life more generally if we study change instead of stasis? Carter Phipps' book, Evolutionaries: Unlocking the Spiritual and Cultural Potential of Science's Greatest Idea, delves deep into this relatively new development. Phipps generally takes as a given the validity of the Modern Synthesis of evolutionary biology. His story takes us into, as the subtitle suggests, the spiritual and cultural implications of evolutionary thinking. Can religion and evolution be reconciled? Can evolutionary thinking lead to a new type of spirituality? Is our culture already being changed in ways that we don't realize by evolutionary thinking? These are all important questions and Phipps book is a great introduction to this discussion. Phipps is an author, journalist, and contributor to the emerging "integral" or "evolutionary" cultural movement that combines the insights of Integral Philosophy, evolutionary science, developmental psychology, and the social sciences. He has served as the Executive Editor of EnlightenNext magazine (no longer published) and more recently is the co-founder of the Institute for Cultural Evolution, a public policy think tank addressing the cultural roots of America's political challenges. What follows is an email interview with Phipps.

  1. A revision of the haploporinae nicoll, 1914 (digenea: haploporidae) from mullets (mugilidae): two new haploporine genera and a key to the genera of the subfamily.

    Science.gov (United States)

    Blasco-Costa, Isabel; Montero, Francisco E; Gibson, David I; Balbuena, Juan Antonio; Kostadinova, Aneta

    2009-03-01

    Two new haploporine genera are established for parasites of mullets. Ragaia n. g. is erected for R. lizae n. sp. from Liza ramado in the Ebro Delta on the Mediterranean Coast of Spain. This new genus is distinguished by the unique combination of the following characters: a strongly muscular ventral sucker which is twice as large as the oral sucker; a large, muscular hermaphroditic sac similar in length to the ventral sucker; a saccular, thick-walled internal seminal vesicle which is larger than the external seminal vesicle; and the ovary and vitellarium located rather close to the posterior extremity. Pseudodicrogaster n. g. is erected to accommodate Dicrogaster japonica Machida, 1996, as P. japonica (Machida, 1996) n. comb., a parasite of Mugil cephalus L. off Fukaura, Japan. This genus is recognised on the basis of: the tubular condition of both the internal and external seminal vesicles, the latter being much shorter than the former; the sucker ratio; the massive pyriform hermaphroditic sac; the location of the testis; and the presence of two eye-spots in developed miracidia. A key to the nine recognised genera of the Haploporinae is presented.

  2. The Orchestras of the Príncipe and Cruz Coliseums in Madrid during the Second Half of the 18th Century

    Directory of Open Access Journals (Sweden)

    Marina BARBA

    2016-06-01

    Full Text Available There were no stable orchestras in Madrid’s public theatres during the first half of the Eighteenth Century, and a variable number of instrumentalists were used on each occasion. This paper discusses the development of the two town-owned theatres in the second half of the century, when the orchestra was considered an important element and a new way of hiring musicians developed, based on sources kept at the Archivo de Villa de Madrid, Sección de Secretaría.René Andioc and Mireille Coulon in their Cartelera teatral madrileña del siglo XVIII: (1708-1808 refer to the companies that worked in both theatres in the second half of the 18th Century, those of de Josef de Parra, María Hidalgo, José Martínez Gálvez, Juan Ángel, Águeda de la Calle, María Ladvenant, Nicolás de la Calle, Juan Ponce, Manuel Martínez, Eusebio Ribera, Joaquín Palomino, Luis Navarro and Francisco Ramo, although they do not study the orchestral musicians. The first study on this issue is that by José Máximo Leza «Las orquestas de ópera en Madrid entre los siglos XVIII-XIX», although it does not discuss the theatres of La Cruz and El Príncipe in the second half of the century. 

  3. Corn stover harvest strategy effects on grain yield and soil quality indicators

    International Nuclear Information System (INIS)

    Douglas, K.; Stuart, B.; Adam, W.

    2013-01-01

    Developing strategies to collect and use cellulo sic biomass for bio energy production is important because those materials are not used as human food sources. This study compared corn (Zea mays L.) stover harvest strategies on a 50 ha Clarion- Nicol let-Webster soil Association site near Emmetsburg, Iowa, USA. Surface soil samples (0 to 15 cm) were analyzed after each harvest to monitor soil organic carbon (Soc), ph, phosphorus (P) and potassium (K) changes. Grain yields in 2008, before the stover harvest treatments were imposed, averaged 11.4 Mg ha-1. In 2009, 2010, and 2011 grain yields averaged 10.1, 9.7, and 9.5 Mg ha-1, respectively. Although grain yields after stover harvest strategies imposed were lower than in 2008, there were no significant differences among the treatments. Four-year average stover collection rates ranged 1.0 to 5.2 Mg ha-1 which was 12 to 60% of the above-ground biomass. Soc showed a slight decrease during the study, but the change was not related to any specific stover harvest treatment. Instead, we attribute the Soc decline to the tillage intensity and lower than expected crop yields. Overall, these results are consistent with other Midwestern USA studies that indicate corn stover should not be harvested if average grain yields are less than 11 Mg ha-1

  4. Nanopharmaceuticals (part 1: products on the market

    Directory of Open Access Journals (Sweden)

    Weissig V

    2014-09-01

    Full Text Available Volkmar Weissig,1 Tracy K Pettinger,2 Nicole Murdock3 1Department of Pharmaceutical Sciences, Midwestern University College of Pharmacy Glendale, Glendale, AZ, USA; 2Department of Pharmacy Practice and Administrative Sciences, College of Pharmacy, Idaho State University, Pocatello, ID, USA; 3Department of Pharmacy Practice, Midwestern University College of Pharmacy Glendale, Glendale, AZ, USA Abstract: In 2000, the National Institute of Health launched the National Nanotechnology Initiative to support, coordinate, and advance research and development of nanoscale projects. The impact of this new program on health-science related research and development became quickly visible. Broad governmental financial support advanced the start of new, and the deepening of already existing, interdisciplinary research. The anticipated merger of nanoscience with medicine quickly instigated the conceptualization of nanomedicine. The adoption of nanoscience terminology by pharmaceutical scientists resulted in the advent of nanopharmaceuticals. The term “nano” became tantamount to “cutting-edge” and was quickly embraced by the pharmaceutical science community. Colloidal drug delivery systems reemerged as nanodrug delivery systems; colloidal gold became a suspension of nano gold particles. In this review, we first review nanoscience related definitions applied to pharmaceuticals, we then discuss all 43 currently approved drug formulations which are publicized as nanopharmaceuticals, and finally we analyze clinical aspects of selected drug formulations. Keywords: amphotericin-B, fenofibrate, nanodrugs, nanomedicine, nanoparticle, drug delivery

  5. Are women the next driving force in mining?

    Energy Technology Data Exchange (ETDEWEB)

    Perry, J.

    2007-07-15

    A symposium entitled 'Women in mining' was held as part of Australia's Minerals Week 2007, on 29 May in Canberra, ACT. In July 2007, Engineers Australia together with Association of Professional Engineers Scientists and Managers, Australia held a women's conference in Melbourne. A survey carried out identified the two main obstacles to women's career advancement: balancing work and life, followed by workplace culture. The majority of female respondents of a recent survey by the Australian Institute of Mining and Metallurgy were concentrated around the early to intermediate stages of their career whereas male respondents were clustered around senior positions. These findings are in line with a report commissioned by the mineral industry and the federal government 'Unearthing new resources: attracting and retaining women in the Australian mineral industry', released in May. This found that the age profile of women in the industry is concentrated towards those aged 34 and under. Lack of child care was cited as the major reason for leaving the industry. A lack of mentor relationships and support networks for women was identified. The article reports comments by Nicole Hollows, Macarthur Coal's CEO and recently appointed managing director, and others who attended the 'Women in mining symposium'. 1 ref., 6 photos.

  6. Early-life chemical exposures and risk of metabolic syndrome

    Directory of Open Access Journals (Sweden)

    De Long NE

    2017-03-01

    Full Text Available Nicole E De Long, Alison C Holloway Department of Obstetrics and Gynecology, McMaster University, Hamilton, ON, Canada Abstract: The global prevalence of obesity has been increasing at a staggering pace, with few indications of any decline, and is now one of the major public health challenges worldwide. While obesity and metabolic syndrome (MetS have historically thought to be largely driven by increased caloric intake and lack of exercise, this is insufficient to account for the observed changes in disease trends. There is now increasing evidence to suggest that exposure to synthetic chemicals in our environment may also play a key role in the etiology and pathophysiology of metabolic diseases. Importantly, exposures occurring in early life (in utero and early childhood may have a more profound effect on life-long risk of obesity and MetS. This narrative review explores the evidence linking early-life exposure to a suite of chemicals that are common contaminants associated with food production (pesticides; imidacloprid, chlorpyrifos, and glyphosate and processing (acrylamide, in addition to chemicals ubiquitously found in our household goods (brominated flame retardants and drinking water (heavy metals and changes in key pathways important for the development of MetS and obesity. Keywords: obesity, pesticides, polybrominated diphenyl ethers, heavy metals, acrylamide, endocrine-disrupting chemicals

  7. The Madrid School of Neurology (1885-1939).

    Science.gov (United States)

    Giménez-Roldán, S

    2015-01-01

    The emergence of neurology in Madrid between 1885 and 1939 had well-defined characteristics. On foundations laid by Cajal and Río-Hortega, pioneers combined clinical practice with cutting-edge neurohistology and neuropathology research. Luis Simarro, trained in Paris, taught many talented students including Gayarre, Achúcarro and Lafora. The untimely death of Nicolás Achúcarro curtailed his promising career, but he still completed the clinicopathological study of the first American case of Alzheimer's disease. On returning to Spain, he studied glial cells, including rod cells. Rodríguez Lafora described progressive myoclonus epilepsy and completed experimental studies of corpus callosum lesions and clinical and neuropathology studies of senile dementia. He fled to Mexico at the end of the Spanish Civil War (1936-1939). Sanchís Banús, a sterling clinical neurologist, described the first cluster of Huntington's disease in Spain, and he and Río-Hortega joined efforts to determine that pallidal degeneration underlies rigidity in advanced stages of the disease. Just after the war, Alberca Llorente eruditely described inflammatory diseases of the neuraxis. Manuel Peraita studied "the neurology of hunger" with data collected during the siege of Madrid. Dionisio Nieto, like many exiled intellectuals, settled in Mexico DF, where he taught neurohistological methods and neuropsychiatry in the tradition of the Madrid School of Neurology. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  8. A brief information–motivation–behavioral skills intervention to promote human papillomavirus vaccination among college-aged women

    Directory of Open Access Journals (Sweden)

    Perez GK

    2016-10-01

    Full Text Available Giselle K Perez,1 Dean G Cruess,2 Nicole M Strauss,3 1Department of Psychiatry, Massachusetts General Hospital, Boston, MA, 2Department of Psychology, University of Connecticut, Storrs, CT, 3Mongan Institute for Health Policy, Massachusetts General Hospital, Boston, MA, USA Background: Human papillomavirus (HPV is prevalent among college-aged women. Although HPV vaccines decrease women’s risk for cervical cancer, the vaccination rates remain inadequate.  Objective: This study explored the utility of an information–motivation–behavioral skills (IMB intervention in promoting HPV vaccination knowledge, motivation, and intentions among college-aged women. Methods: In Spring/Fall 2012, 62 participants were randomly assigned to a single-session intervention or attention control and were assessed baseline, post-intervention, and at 1 month. Results: The participants demonstrated adequate baseline vaccine knowledge, low HPV/cancer knowledge, and ambivalence about the vaccination. Post-intervention, the IMB arm demonstrated increased HPV/cancer and vaccination knowledge, motivation, and intentions. There were no group differences in vaccination at 1 month; however, the odds of wanting to get vaccinated increased sevenfold in the IMB arm. Conclusion: These results provide preliminary support for an IMB-based intervention in increasing vaccination knowledge, motivation, and intentions among at-risk women. Future research examining the efficacy of longer trials with larger, diverse populations is warranted. Keywords: human papillomavirus, HPV, vaccination, cervical cancer, Gardasil, IMB

  9. Ethical Issues for Direct-to-Consumer Digital Psychotherapy Apps: Addressing Accountability, Data Protection, and Consent.

    Science.gov (United States)

    Martinez-Martin, Nicole; Kreitmair, Karola

    2018-04-23

    This paper focuses on the ethical challenges presented by direct-to-consumer (DTC) digital psychotherapy services that do not involve oversight by a professional mental health provider. DTC digital psychotherapy services can potentially assist in improving access to mental health care for the many people who would otherwise not have the resources or ability to connect with a therapist. However, the lack of adequate regulation in this area exacerbates concerns over how safety, privacy, accountability, and other ethical obligations to protect an individual in therapy are addressed within these services. In the traditional therapeutic relationship, there are ethical obligations that serve to protect the interests of the client and provide warnings. In contrast, in a DTC therapy app, there are no clear lines of accountability or associated ethical obligations to protect the user seeking mental health services. The types of DTC services that present ethical challenges include apps that use a digital platform to connect users to minimally trained nonprofessional counselors, as well as services that provide counseling steered by artificial intelligence and conversational agents. There is a need for adequate oversight of DTC nonprofessional psychotherapy services and additional empirical research to inform policy that will provide protection to the consumer. ©Nicole Martinez-Martin, Karola Kreitmair. Originally published in JMIR Mental Health (http://mental.jmir.org), 23.04.2018.

  10. [Localized scleroderma: a retrospective study about 92 cases].

    Science.gov (United States)

    El Fékih, Nadia; Réjaibi, Iménc; Kamoun, Hajer; Zéglaoui, Faten; Fazaa, Bécima; Kharfi, Monia; Kamoun, Mohamed Ridha

    2009-09-01

    Sclerodermas are rare affections which can be located or generalized. Localized form is the most frequent. The purpose of this study was to describe epidemiologic, clinics, biological, immunological, therapeutic, evolutionary characteristics of the localized scleroderma through a personal series and the data of the literature. We have performed a retrospective study on all patients followed in the department of dermatology of the Hospital Charles Nicole during 14 years period. Our study was about 92 cases of localized scleroderma (73 were females and 19 males). The mean age was 35 years (between 2 and 72 years). The majority of localised sclerodermas (66.2% of the cases) appeared before 40 years with a maximum of frequency between 10 and 30 years (41.6%). Only 11.9% of the cases were observed before 10 years. They were 51 cases (55%) of morphea, 35 cases (38%) of scleroderma in bands including 32 linear scleroderma and 3 scleroderma en coup de sabre, 5 cases (5.5%) of generalized morphea and 1 case (0.15%) of deep morphea. Average therapeutic was specified among 63 patients (87%), and the evolution could be appreciated among 45 patients. The epidemiologic data observed in our series are comparable with those reported in the literature. Therapeutic difficulties and risks of functional after-effects, particular in scleroderma in bands, remain the principal concern for all the authors.

  11. THE PRODUCTION OF MEZCAL IN THE MUNICIPALITY OF DURANGO, MEXICO

    Directory of Open Access Journals (Sweden)

    Sixto Barraza-Soto

    2014-07-01

    Full Text Available In Durango Municipality there are six enterprises which elaborate mezcal, four of them are certified. Row matter is extracted from wild plantations, 72% comes from the fields of the Ejido Nicolás Romero. The possible production of mezcal is 528,092 liters per year; this quantity exceeds 5 times the maximum production projected, according to the installed infrastructure capacity. Certified enterprises have higher production costs but also have better benefits than “vinatas”. The price of a 750 ml mezcal bottle is $138.00 pesos plus tax, while the price of a bottle of the same capacity produced in rustic enterprises fluctuates between $30.00 y $70.00 pesos. Certified enterprises produce the mezcal following the production and packaging criteria of the NOM-070-SCFI-1994. Rustic enterprises do not follow this Rule, storing and selling the product in any kind of bottle either of glass or plastic. The conclusion is that mezcal production is profitable if the producers are associated and certify the product, especially in the production of maguey and in the packaging process. This on one hand would help preserve biodiversity in the sites where the plant is extracted now, and, on the other hand, it would decrease the intervention of intermediaries contributing to obtaining higher incomes for mezcal producers.

  12. Recruitment and Participation of Recreational Runners in a Large Epidemiological and Genetic Research Study: Retrospective Data Analysis.

    Science.gov (United States)

    Manzanero, Silvia; Kozlovskaia, Maria; Vlahovich, Nicole; Hughes, David C

    2018-05-23

    With the increasing capacity for remote collection of both data and samples for medical research, a thorough assessment is needed to determine the association of population characteristics and recruitment methodologies with response rates. The aim of this research was to assess population representativeness in a two-stage study of health and injury in recreational runners, which consisted of an epidemiological arm and genetic analysis. The cost and success of various classical and internet-based methods were analyzed, and demographic representativeness was assessed for recruitment to the epidemiological survey, reported willingness to participate in the genetic arm of the study, actual participation, sample return, and approval for biobank storage. A total of 4965 valid responses were received, of which 1664 were deemed eligible for genetic analysis. Younger age showed a negative association with initial recruitment rate, expressed willingness to participate in genetic analysis, and actual participation. Additionally, female sex was associated with higher initial recruitment rates, and ethnic origin impacted willingness to participate in the genetic analysis (all P<.001). The sharp decline in retention through the different stages of the study in young respondents suggests the necessity to develop specific recruitment and retention strategies when investigating a young, physically active population. ©Silvia Manzanero, Maria Kozlovskaia, Nicole Vlahovich, David C Hughes. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 23.05.2018.

  13. The Romanesque Bronze Doors at Gniezno Cathedral Church: Some New Remarks

    Directory of Open Access Journals (Sweden)

    Tomasz Węcławowicz

    2017-06-01

    Full Text Available Among many Romanesque bronze doors in Europe the old entrance doors of the metropolitan cathedral in Gniezno, in the North Poland, are exceptional. For over a century many historians and historians of art have been trying to understand and explain its iconographic phenomenon. The Polish, Czech and German scholars have so far been unable to identify with any conviction, either the iconographic models or artistic provenance of the workshop. There were suggested some connections of the alleged bishop patrons to France and there were emphasizes technological possibilities of foundry workshops at the Meuse Valley. This “Meuse hypothesis” based mainly on historical suggestions became established as a certainty. However, it is important to emphasize the significant difference between the creator of the composition and of the craftsman who cast the bronze door. Years ago only Lech Kalinowski pointed out some general formal similarities to the North Italian sculpture. The purpose of this paper is to develop Kalinowski’s suggestions and to emphasise the puzzling similarities between details of Gniezno doors and some Emilian works executed by Master Wiligelmo da Modena and Master Nicolò. The concept of Italian relationship from Emilia province seems to be better for the comparative analysis than relationship with Meuse Valley based mostly on historical context. Crucial here is the additional, parallel analysis of the portal decoration in Czerwinsk Abbey.

  14. Reforestation of bauxite mine spoils with Eucalyptus tereticornis Sm. seedlings inoculated with arbuscular mycorrhizal fungi

    Directory of Open Access Journals (Sweden)

    N. Krishnakumar

    2012-11-01

    Full Text Available Open cast mining for bauxite at Yercaud hills (India resulted indegradation of forest ecosystem and production of large quantities of waste rocks (called mine spoils. To ameliorate mine spoils, topsoil is used to spread over before the planting of tree species, conventional method as the topsoil has a good structure, water holding capacity and beneficial microbes like Arbuscular Mycorrhizal (AM fungi essential for plant growth.However, the use of top soil is expensive and in this study bauxite mine spoils were reforestated with AM fungi instead of it. The beneficial microbes AM fungi (Glomus aggregatum Schenck & Smith, G. fasciculatum(Thatcher Gerd. & Trappe emend. Walker & Koske, G. geosporum(Nicol. & Gerd. Walker were isolated, cultured and inoculated into the seedlings of Eucalyptus tereticornis Sm. and grown in bauxite mine spoils as potting medium under nursery conditions. Then, the biomass improved seedlings of E. tereticornis with inoculation of AM fungi were directly transplanted at bauxite mine spoils. After transplantation of the seedlings at bauxite mine spoils, the growth and survival rate were monitored for two years. The AM fungi inoculated seedlings of E. tereticornis showed 95% survival over the control seedlings and their growth was also significantlyhigher. Tissue nutrients (N, P, K were also found higher inAM fungi inoculated E. tereticornis than un inoculated control seedlings.

  15. Reforestation of Bauxite mine spoils with Eucalyptus tereticornis Sm. seedlings inoculated with Arbuscular mycorrhizal fungi

    Directory of Open Access Journals (Sweden)

    A. Karthikeyan

    2012-12-01

    Full Text Available Open cast mining for bauxite at Yercaud hills (India resulted in degradation of forest ecosystem and production of large quantities of waste rocks (called mine spoils. To ameliorate mine spoils, topsoil is used to spread over before the planting of tree species, conventional method as the topsoil has a good structure, water holding capacity and beneficial microbes like Arbuscular Mycorrhizal (AM fungi essential for plant growth. However, the use of top soil is expensive and in this study bauxite mine spoils were reforestated with AM fungi instead of it. The beneficial microbes AM fungi (Glomus aggregatum Schenck & Smith, G. fasciculatum (Thatcher Gerd. & Trappe emend. Walker & Koske, G. geosporum (Nicol. & Gerd. Walker were isolated, cultured and inoculated into the seedlings ofEucalyptus tereticornis Sm. and grown in bauxite mine spoils as potting medium under nursery conditions. Then, the biomass improved seedlings of E. tereticornis with inoculation of AM fungi were directly transplanted at bauxite mine spoils. After transplantation of the seedlings at bauxite mine spoils, the growth and survival rate were monitored for two years. The AM fungi inoculated seedlings ofE. tereticornis showed 95% survival over the control seedlings and their growth was also significantly higher. Tissue nutrients (N, P, K were also found higher in AM fungi inoculated E. tereticornis than un inoculated control seedlings. 

  16. Evaluation of some fungicides on mycorrhizal symbiosis between two Glomus species from commercial inocula and Allium porrum L. seedlings

    Energy Technology Data Exchange (ETDEWEB)

    Hernandez-Dorrego, A.; Mestre Pares, J.

    2010-07-01

    This paper reports the effect of twenty-five commonly used fungicides in agriculture on two arbuscular mycorrhizal fungi (AMF) present in commercial products of ATENS, S.L.: Glomus intra radices (Schenck and Smith) and Glomus mosseae [(Nicol. and Gerd.) Gerdemann and Trappe], forming the symbiosis with leek plants. Systemic fungicides (Aliette, Beltanol, Caddy 10, Forum, Moncut, Ortiva, Previcur, Ridomil Gold MZ, Ridomil Gold SL, Rubigan, Sinthane, Stroby, Swich, Tachigarem, Teldor, Topas 10 EC, Frupica) and non systemic fungicides (Daconil 75%, Ditiver, Euparem, INACOP, Octagon, Parmex, Terrazole and Metaram), started to be applied to soil and leaves at recommended concentrations and frequencies 4 weeks after transplant and AMF inoculation. The effect of the fungicides was assessed by comparing treated and untreated plants that were inoculated with the AMF through quantification of root mycorrhizal colonization. Among the fungicides applied to the soil, Octagon, Ditiver, Parmex and Metaram virtually eliminated the mycorrhizal symbiosis in treated plants, while the mycorrhizal colonization was not affected by the soil treatment with Beltanol, INACOP and Previcur. Three fungicides of foliar recommended application: Rubigan, Frupica, and Sinthane, strongly inhibited mycorrhizal colonization, but Aliette, Forum, Teldor, Swich and Ortiva, did not seem to reduce it substantially. In addition, the work describes the individual effect of each fungicide applied on both, foliage and soil. (Author) 29 refs.

  17. La metáfrasis de la Ilíada al griego vulgar. A propósito de la Ilíada de Nicolás Lucanis

    Directory of Open Access Journals (Sweden)

    Pedro Bádenas de la Peña

    1995-06-01

    Full Text Available The illustrated Iliad printed in Venice in 1526 is a rare book which is interesting in several ways: a It is the first Iliad in a modern European language, it is not a translation of the Homeric text but an adaptation or, much better, a «metaphrasis» in trochaicus octosyllabic verses from a byzantine version. b Until the Apócopos by Bergadis in Cretan dialect appeared (Venice 1509, this Iliad was the first book printed in modern Greek. c The metaphrasis by Lukanis shows an important publishing activity dedicated to the emigrant Greek people, to the readers of the Greek lands depending on Venice yet, as well as to the Greek speakers of the Ottoman Empire. d Culturally speaking. Lukanis’ Iliad demonstrates that in the 16th century a byzantine pattern of rhetorical vulgarization of the classical works was valid, that was the Hermoniakos’ Iliad.

  18. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2008-12-01

    Guerra, Armin Schwegler; Lengua y ritos del Palo Monte Mayombe: Dioses cubanos y sus fuentes africanas (W. van Wetering Mary Ann Clark; Where Men Are Wives and Mothers Rule: Santería Ritual Practices and Their Gender Implications (Elizabeth Ann Pérez Ignacio López-Calvo; “God and Trujillo”: Literary and Cultural Representations of the Dominican Dictator (Lauren Derby Kirwin R. Shaffer; Anarchism and Countercultural Politics in Early Twentieth-Century Cuba (Jorge L. Giovannetti Lillian Guerra; The Myth of José Martí: Conflicting Nationalisms in Early Twentieth-Century Cuba (Jorge L. Giovannetti Israel Reyes; Humor and the Eccentric Text in Puerto Rican Literature (Nicole Roberts Rodrigo Lazo; Writing to Cuba: Filibustering and Cuban Exiles in the United States (Nicole Roberts Lowell Fiet; El teatro puertorriqueño reimaginado: Notas críticas sobre la creación dramática y el performance (Ramón H. Rivera-Servera Curdella Forbes; From Nation to Diaspora: Samuel Selvon, George Lamming and the Cultural Performance of Gender (Sue Thomas Marie-Agnès Sourieau, Kathleen M. Balutansky (eds.; Ecrire en pays assiégé: Haiti: Writing Under Siege (Marie-Hélène Laforest In: New West Indian Guide / Nieuwe West-Indische Gids (NWIG, 80 (2006, no. 3 & 4

  19. Bupivacaína racêmica, levobupivacaína e ropivacaína em anestesia loco-regional para oftalmologia: um estudo comparativo Racemic bupivacaine, levobupi vacaine and ropivacaine in regional anesthesia for ophtalmology: a comparative study

    Directory of Open Access Journals (Sweden)

    Edno Magalhães

    2004-04-01

    Full Text Available OBJETIVO: A bupivacaína racêmica, utilizada largamente em anestesia peribulbar devido à boa qualidade de bloqueio motor, apresenta menor margem de segurança para cardiotoxicidade em relação a ropivacaína e bupivacaína levógira. O objetivo deste estudo foi comparar o grau de bloqueio motor e alteração da pressão intra-ocular (PIO em anestesia peribulbar produzida pela bupivacaína racêmica, levobupivacaína e ropivacaína. MÉTODOS: Noventa e sete pacientes, estado físico I e II da classificação da Sociedade Americana de Anestesiologistas, submetidos a anestesia peribulbar, foram divididos em três grupos: grupo A-(n=16 bupivacaína racêmica 0,75% com adrenalina 1:200.000; grupo B -(n=16 bupivacaína levógira 0,75% com adrenalina 1:200.000; grupo C -(n=15 ropivacaína 0,75%. Utilizou-se 7ml da solução anestésica com 280 UI de hialuronidase, em punção única no rebordo orbital inferior. Foram registrados a PIO e grau de bloqueio motor 5 minutos antes da punção e 1, 2, 3, 4, 5 e 10 minutos após a punção. O bloqueio motor foi avaliado pela escala de Nicoll. Para a análise estatística, foram utilizados os testes de Wilcoxon, análise de freqüência simples e t de Student. Foi considerado significativo pBACKGROUND AND OBJECTIVE: Racemic bupivacaine, used in peribulbar anesthesia owing to its high potential to promote motor blockade, presents a smaller safety margin for cardiotoxicity in relation to ropivacaine and levobupivacaine. The objective of this study was to compare the degree of motor blockade and alteration of intraocular pressure (IOP produced by racemic bupivacaine, levobupivacaine and ropivacaine in peribulbar block. METHOD: Ninety seven patients, ASA physical status I and II, submitted to peribulbar anesthesia, were randomly allocated into three groups: group A-(n=16 receiving racemic bupivacaine 0.75% with epinephrine 1:200.000; group B -(n=16 levobupivacaine 0.75% with epinephrine 1:200.000; group C -(n=15

  20. STEeM- STEM&eTwinning in my school

    Science.gov (United States)

    Nicolaita, Cristina

    2017-04-01

    My name is Cristina Nicolăiță, I am a teacher of Physics and Computer Science in Gheorghe Magheru School, Caracal, Romania, and a Romanian Scientix&eTwinning ambassador. My poster presents the two eTwinning projects my students are actively involved in, "STEM Club" and "What's the weather like #eTwCitizen2016", with partners mostly from the Mediterranean area. STEM CLUB project focuses on the introductory level STEM activities, as well as awareness of the STEM fields and occupations. This initial step provides standards-based structured inquiry-based and real world problem-based learning, connecting all four of the STEM subjects. Project's basic aims are: 1. increasing student STEM ability, engagement, participation and aspiration 2. increasing teacher capacity and STEM teaching quality 3. supporting STEM education opportunities 4. facilitating effective school partnerships 5. building a strong evidence base 6. improving ICT skills During the second eTwinning project, What's the weather like #eTwCitizen2016", students will investigate weather in our lives, culture and science, in literature (including popular sayings and informative digital literacy), languages, science and Maths( including astronomy, physics, environmental studies) social sciences, religion, art, music, history, psychology (ways of thinking at different weather conditions, feelings related with the weather forecast, careers related to weather, climate change and sustainability).They will use the different intelligences they possess, bringing their contribution to the team work and developing the ability to identify, find, evaluate, and use information effectively.

  1. A Hot Downflowing Model Atmosphere for Umbral Flashes and the Physical Properties of Their Dark Fibrils

    Energy Technology Data Exchange (ETDEWEB)

    Henriques, V. M. J.; Mathioudakis, M. [Astrophysics Research Centre, School of Mathematics and Physics, Queen’s University Belfast, BT7 1NN, Northern Ireland (United Kingdom); Socas-Navarro, H. [Instituto de Astrofísica de Canarias, Avda vía Láctea S/N, E-38205 La Laguna, Tenerife (Spain); Rodríguez, J. de la Cruz, E-mail: v.henriques@qub.ac.uk [Institute for Solar Physics, Department of Astronomy, Stockholm University, AlbaNova University Centre, SE-106 91 Stockholm (Sweden)

    2017-08-20

    We perform non-LTE inversions in a large set of umbral flashes, including the dark fibrils visible within them, and in the quiescent umbra by using the inversion code NICOLE on a set of full Stokes high-resolution Ca ii λ 8542 observations of a sunspot at disk center. We find that the dark structures have Stokes profiles that are distinct from those of the quiescent and flashed regions. They are best reproduced by atmospheres that are more similar to the flashed atmosphere in terms of velocities, even if with reduced amplitudes. We also find two sets of solutions that finely fit the flashed profiles: a set that is upflowing, featuring a transition region that is deeper than in the quiescent case and preceded by a slight dip in temperature, and a second solution with a hotter atmosphere in the chromosphere but featuring downflows close to the speed of sound at such heights. Such downflows may be related, or even dependent, on the presence of coronal loops, rooted in the umbra of sunspots, as is the case in the region analyzed. Similar loops have been recently observed to have supersonic downflows in the transition region and are consistent with the earlier “sunspot plumes,” which were invariably found to display strong downflows in sunspots. Finally, we find, on average, a magnetic field reduction in the flashed areas, suggesting that the shock pressure is moving field lines in the upper layers.

  2. ‘You think your writing belongs to you?’: Intertextuality in Contemporary Jewish Post-Holocaust Literature

    Directory of Open Access Journals (Sweden)

    Kirstin Gwyer

    2018-03-01

    Full Text Available This article examines a sub-category of recent Jewish post-Holocaust fiction that engages with the absent memory of the persecution its authors did not personally witness through the medium of intertextuality, but with intertextual recourse not to testimonial writing but to literature only unwittingly or retrospectively shadowed by the Holocaust. It will be proposed that this practice of intertextuality constitutes a response to the post-Holocaust Jewish author’s ‘anxiety of influence’ that, in the wake of the first generation’s experience of atrocity, their own life story and literature will always appear derivative. With reference to works by four such post-Holocaust authors, Jonathan Safran Foer’s Tree of Codes (2010, Maxim Biller’s Im Kopf von Bruno Schulz (2013, Helen Maryles Shankman’s In the Land of Armadillos (2016, and Nicole Krauss’s The History of Love (2005 and Forest Dark (2017, all of which engage intertextually with Franz Kafka and Bruno Schulz, it will be suggested that these authors are looking to return to a Kristevan practice of intertextuality after the predominantly citational recourse to antecedent material that has often characterized post-Holocaust literature. In the process, they also succeed in troubling recently popular conceptualizations of ‘postmemory’ literature as the ‘belated’ and ‘evacuated’ recipient of encrypted traumatic content inherited from the first generation that it must now seek either to preserve or to work through vicariously.

  3. El viaje a Portugal de los embajadores de Federico III en el relato de Lanckmann y de otros cronistas

    Directory of Open Access Journals (Sweden)

    Herbers, Klaus

    2002-06-01

    Full Text Available The article analyses the report by Nicolas Lanckmann and Jacob Motz of the trip they undertook in 1451 to Lisbon in order to accompany Eleonore of Portugal, future wife to Frederic III, to Rome. Special importance is given to the role safe-conducts and Jacobean traditions play in the text, and the motives for taking the Northern route through the Iberian Peninsula and for diverting to Santiago de Compostela during the time of the "Año Santo" are examined. The report's wide circulation during the XVth and XVIth centuries underlines the ways one formed an image of the Iberian Peninsula in the countries of German tongue.

    El artículo analiza el relato de Nicolás Lanckmann y Jacobo Motz sobre el viaje que éstos emprendieron hacia Lisboa en 1451 para llevar a la futura esposa de Federico III, Leonor de Portugal, a Roma. Se destaca el papel de los salvoconductos y de las tradiciones jacobeas, y se estudian asimismo los motivos para elegir la ruta por el norte de España y el desvío hacia Santiago de Compostela durante el Año Santo compostelano. La difusión del relato en los siglos XV y XVI subraya como se formó también en los países de lengua alemana una idea de la Península Ibérica.

  4. The Governor of Michoacán and the University Conflict of 1949. The Vision of Nemesio García Naranjo

    Directory of Open Access Journals (Sweden)

    Francisco Alejandro García naranjo

    2017-07-01

    Full Text Available This article analyzes texts written by the journalist Nemesio García Naranjo, which discussed the events unleashed between the 28 of July and the 26 of August of 1949 in Morelia, Michoacán (Mexico, in a confrontation between the students and authorities of Universidad Michoacana de San Nicolás de Hidalgo, and the State Governor, Jose María Mendoza Pardo, a member of the governing party. The conflict was detonated by the death of two university students in the hands of the army. This event triggered marches and university strikes in the whole country, putting the governability of the state of Michoacán into crisis. The journalistic corpus written by García Naranjo is analyzed in two directions. On the one hand, it emphasizes the liberal position with which this author examined the events and their social and political repercussions for the regime. This ideological positioning contravenes the wrong place in which historiography has put this character: as part of the reactionary and antirevolutionary right. On the other hand, in demostrating that this journalist exhibited a way of thinking proper to the ´liberal right´, we also establish that he judged the events of Morelia and the role of Universidad Michoacana from this perspective, demostrating a dissonant voice in a scenario dominated by ideological biases and political interests, which unanimously accused “the communist conspiracy” as responsable agent.

  5. Chavism and Criminal Policy in Venezuela, 1999-2014

    Directory of Open Access Journals (Sweden)

    Martha Lia Grajales

    2017-03-01

    Full Text Available For a long time, the Venezuelan democracy was an exception in South America due to a party system that was based on what was known as the ‘Punto Fijo Pact’. At the start of the 1980s a series of economic, social and political events began to occur, which caused this ‘exceptionalism’ to stagger and disrupt the institutionality of the traditional Venezuelan democratic State. The events led to a deep national crisis and the birth of a new political era. By the end of the 1990s, there had been a significant shift towards left-wing governance. Hugo Chávez Frías subsequently won the presidential elections in 1998. This paper analyzes some aspects of the criminal policies that were implemented during the reign of left-wing leader Chávez till his death in 2013 and thereafter by Chavist party president elect, Nicolás Maduro during 2013-2014. Four stages can be identified in the behavior of incarceration rates. The first stage, from 1999 to 2000, was characterized by the lowest recordings of incarceration rates and the lowest measured percentage of preventive detention in Venezuela in thirty years. The second stage, from 2001 to 2005, saw a slight increase in the incarceration rate which then remained stable. The third stage, from 2006 to 2012, and the fourth stage, from 2013 to 2014, are characterized by sustained increases in preventive detention, incarceration and murder rates.

  6. Molecular Identification of Leishmania spp. in Sand Flies (Diptera: Psychodidae: Phlebotominae) in the Lençóis Maranhenses National Park, Brazil.

    Science.gov (United States)

    Pereira-Filho, Adalberto Alves; Fonteles, Raquel Silva; Bandeira, Maria da Conceição Abreu; Moraes, Jorge Luiz Pinto; Rebêlo, José Manuel Macário; Melo, Maria Norma

    2018-02-20

    Sand flies are very common in the region of Lençóis Maranhenses National Park, an important tourist attraction in Brazil. However, the role of some species and their relative importance locally in Leishmania Ross 1903 transmission is unclear. The objective of this study was to identify Leishmania infection in phlebotomine sand flies collected around the Lençóis Maranhenses National Park, an important conservation area and popular international/national tourist destination with a high incidence of leishmaniasis. Sand flies were collected in peridomiciliary areas on the tourist route from September 2012 to August 2013. The captured females were subjected to molecular analyses for the detection of Leishmania DNA. Sand flies were infected with four Leishmania species: Leishmania (Viannia) braziliensis (Vianna, 1911) was found in Lutzomyia whitmani (Antunes and Coutinho, 1939) (2.1%) and Lutzomyia longipalpis (Lutz and Neiva, 1912) (1.7%); Leishmania (Leishmania) infantum (Nicole, 1908) infected Lutzomyia wellcomei (Fraiha, Shaw, and Lainson, 1971) (20%), Lutzomyia sordellii (Shannon and Del Ponte, 1927) (4.3%), Lu. longipalpis (3.7%), and Lu. whitmani (0.8%); Leishmania (Leishmania) amazonensis (Lainson & Shaw, 1972) was found in Lu. whitmani (0.58%), while Leishmania (Viannia) lainsoni infected Lutzomyia evandroi (Costa Lima and Antunes, 1936) (3.4%), Lu. longipalpis (1.06%), and Lu. whitmani (0.29%). The occurrence of these parasites requires control measures to reduce the incidence of cutaneous leishmaniasis and to contain a possible epidemic of visceral leishmaniasis, the most severe form of the disease.

  7. On closure strategy for 1-D thermohydraulics models and closure relationships of two-phase flows in simple and subchannel geometry for NPP accident conditions

    International Nuclear Information System (INIS)

    Kornienko, Y.; Kornienko, E.; Ninokata, H.

    2001-01-01

    One-dimensional mathematical models are extensively used in thermohydraulics assessment of Nuclear Power Plant (NPP) transients and accidents, because specifically 1-D system of the conservation laws allows to reduce computing time and required memory, especially in ''best estimate'' code calculations. This work is generalization of the well-known Zuber-Findley and Hancox-Nicoll methods for two-phase flow distribution parameters Cs taking into account the non-monotonous void fraction distribution in the transverse direction in terms of two superimposed monotonous profiles. The method is very useful in evaluating the saddle-shape void fraction profile effects. In this work two-phase flow distribution parameters Cs were developed for simple circular and rectangular pipes, and subchannel geometry in a rod bundle. Basic assumptions were power-mode approximations for describing the profiles of local volume flux density, phase velocity and temperature. The general analytical (quadrature) relationships for Cs were obtained and their 3-D illustrations are proposed. Also, we propose generalized formulation and simple approach to construct friction factor, heat and mass transfer coefficients within the gradient hypothesis and boundary layer assumptions. The contribution of momentum, heat and mass transfer as well as their sources and sinks in the channel cross-section are taken into account. In the same way, the friction factor, heat and mass transfer coefficients with the transversal and azimuthal variations being taken into account are proposed for subchannel geometry as well. (author)

  8. CT Coronary Angiography vs. Coronary Artery Calcium Scoring for the Occupational Assessment of Military Aircrew.

    Science.gov (United States)

    Parsons, Iain; Pavitt, Chris; Chamley, Rebecca; d'Arcy, Jo; Nicol, Ed

    2017-02-01

    To ensure flight safety military aircrew undergo regular clinical and occupational assessment. Coronary artery calcium scoring (CACS) has been established as an imaging modality to noninvasively assess coronary artery disease (CAD). CT coronary angiography (CTCA) potentially offers a more accurate assessment of CAD, but has not been formally assessed in military aircrew. This retrospective cohort study is designed to compare the theoretical differences in downstream investigations and occupational outcomes in aircrew with suspected CAD comparing CTCA with existing CACS pathways. A 2-yr retrospective cohort study of consecutive UK military patients who underwent a CTCA and CACS was undertaken. Patient demographics, CTCA and CACS results, and initial and final occupational restrictions were analyzed comparing current UK, Canadian, and U.S. pathways. There were 44 patients who underwent CACS and CTCA. The commonest indication for a CTCA was a positive exercise ECG. Increasing CACS, stenosis severity, and stenosis burden were associated with significantly greater likelihood of occupational restriction (P = occupational restrictions. Two patients with a calcium score ≤10 had at least 1 single vessel stenosis ≥50%. A CTCA pathway is potentially a better discriminator of CAD burden in aircrew when compared with CACS and may reduce downstream testing, allowing a more efficacious approach to CAD assessment in military aircrew.Parsons I, Pavitt C, Chamley R, d'Arcy J, Nicol E. CT coronary angiography vs. coronary artery calcium scoring for the occupational assessment of military aircrew. Aerosp Med Hum Perform. 2017; 88(2):76-81.

  9. Cartografía y cartografía simbólica Las "Theses de Mathematicas, de Cosmographia e Hidrographia" de Vicente De Memije

    Directory of Open Access Journals (Sweden)

    Alfredo J. Morales Martinez

    Full Text Available Resumen Frente a la ruta que desde el siglo XVI enlazaba la Península Ibérica con las islas Filipinas, Vicente de Memije propuso en la Tesis presentada en Manila en 1761, una nueva ruta directa que bordeaba el Cabo de Hornos. Su texto se dedica al rey Carlos III a quien anima a continuar la tarea de evangelización de Asia de sus antecesores, partiendo para ello del archipiélago filipino, que ya desde el siglo XVI había servido de plataforma a las órdenes religiosas para llevar a cabo la conquista espiritual de las tierras asiáticas. También trata de demostrar la necesidad de establecer una cartografía hispánica basada en la medición de los grados de longitud hacia poniente, rechazando las medidas que distintos cosmógrafos habían otorgado a los dominios españoles y al Pacífico. La Tesis presenta como aparato gráfico dos estampas de gran valor científico y artístico. Para confeccionar la primera, firmada por Nicolás de la Cruz Bagay, acudió a diversas fuentes gráficas francesas, inglesas y holandesas, siendo limitadas las informaciones obtenidas en obras españolas. La segunda estampa aparece firmada por Laureano de Atlas y constituye una de las mejores creaciones de la cartografía simbólica.

  10. SR proteins are NXF1 adaptors that link alternative RNA processing to mRNA export.

    Science.gov (United States)

    Müller-McNicoll, Michaela; Botti, Valentina; de Jesus Domingues, Antonio M; Brandl, Holger; Schwich, Oliver D; Steiner, Michaela C; Curk, Tomaz; Poser, Ina; Zarnack, Kathi; Neugebauer, Karla M

    2016-03-01

    Nuclear export factor 1 (NXF1) exports mRNA to the cytoplasm after recruitment to mRNA by specific adaptor proteins. How and why cells use numerous different export adaptors is poorly understood. Here we critically evaluate members of the SR protein family (SRSF1-7) for their potential to act as NXF1 adaptors that couple pre-mRNA processing to mRNA export. Consistent with this proposal, >1000 endogenous mRNAs required individual SR proteins for nuclear export in vivo. To address the mechanism, transcriptome-wide RNA-binding profiles of NXF1 and SRSF1-7 were determined in parallel by individual-nucleotide-resolution UV cross-linking and immunoprecipitation (iCLIP). Quantitative comparisons of RNA-binding sites showed that NXF1 and SR proteins bind mRNA targets at adjacent sites, indicative of cobinding. SRSF3 emerged as the most potent NXF1 adaptor, conferring sequence specificity to RNA binding by NXF1 in last exons. Interestingly, SRSF3 and SRSF7 were shown to bind different sites in last exons and regulate 3' untranslated region length in an opposing manner. Both SRSF3 and SRSF7 promoted NXF1 recruitment to mRNA. Thus, SRSF3 and SRSF7 couple alternative splicing and polyadenylation to NXF1-mediated mRNA export, thereby controlling the cytoplasmic abundance of transcripts with alternative 3' ends. © 2016 Müller-McNicoll et al.; Published by Cold Spring Harbor Laboratory Press.

  11. Effectiveness of weekly cognitive stimulation therapy for people with dementia and the additional impact of enhancing cognitive stimulation therapy with a carer training program

    Directory of Open Access Journals (Sweden)

    Cove J

    2014-12-01

    Full Text Available Jennifer Cove,1 Nicola Jacobi,2 Helen Donovan,3 Martin Orrell,4 Josh Stott,5 Aimee Spector5 1Department of Clinical, Educational and Health Psychology, University College London, London, 2Department of Psychology, City University, London, 3Clinical Psychology Service, South Essex Partnership NHS Foundation Trust, Bedford, 4Department of Psychiatry, 5Department of Clinical, Educational and Health Psychology, University College London, London, UKPurpose of the study: Cognitive stimulation therapy (CST is a widely used, evidence-based intervention for people with dementia (PwD. Although designed as a 14 session, twice weekly intervention, many services in the UK deliver CST once a week for 14 weeks. However, this method of delivery has yet to be evaluated. In addition, CST does not include any formal carer training. This study aimed to evaluate the effectiveness of once weekly CST and determine any additional impact when enhanced with a carer training program.Design and methods: A single blind, randomized controlled trial was conducted. Sixty eight PwD and their carers were recruited through three community Memory Assessment Services. PwD and their carers were randomized to one of three conditions: CST plus carer training, CST only, or a wait list control. PwD were administered standardized measures of cognition, quality of life, and quality of relationship with carer at baseline and the 15 week follow-up.Results: There were no baseline differences across the three groups. At follow-up, there were no significant differences between PwD in the three groups on any outcomes. Implications: Weekly CST with or without carer training may not be an effective form of delivery. Several possible explanations for the outcomes are proposed. Weekly CST may not offer the necessary “dose” required to combat decline, and equally the carer training may have been too brief to have made a difference. Services currently offering weekly CST should collect routine

  12. Influência da adubação com esterco bovino e inoculação de fungos micorrízicos arbusculares no crescimento de mudas de Carica papaya L. (var. Formosa Influence of fertilization with bovine manure and inoculation of arbuscular mycorrhizal fungi in the growth of Carica papaya L. 'Formosa' seedlings

    Directory of Open Access Journals (Sweden)

    Cláudia Elizabete de Lima Lins

    1999-12-01

    Full Text Available Devido ao rápido crescimento do mamoeiro, poucos são os solos que, em condições naturais, podem satisfazer a sua demanda por nutrientes, sendo necessária a aplicação de fertilizantes minerais que favoreçam as plantas no período do transplantio para o campo. Os fungos micorrízicos arbusculares (FMA são conhecidos por tornarem os seus hospedeiros mais resistentes aos estresses bióticos e abióticos, sendo por isso empregados na produção de mudas de diversas árvores frutíferas. Nesse trabalho objetivou-se avaliar a influência da inoculação de FMA e da aplicação de matéria orgânica no crescimento de mudas de mamoeiro (Carica papaya L. var. Formosa, em casa-de-vegetação. Mudas foram cultivadas em solo arenoso (caracterizado pelo baixo teor de P: 4 ppm, inoculado com FMA e adubado ou não com 50g de esterco bovino. O delineamento experimental foi inteiramente casualizado com seis tratamentos e três repetições: - inoculação com FMA nativos, com Gigaspora albida Schenck & Smith, ou com Scutellospora hetervgama (Nicol. & Gerd. Walker & Sanders, com ou sem matéria orgânica O experimento foi avaliado a cada 10 dias, sendo aferidos os parâmetros: altura, diâmetro do caule e número de folhas. Diferenças significativas entre os tratamentos adubados e não adubados foram observados a partir do 30º dia Após 40 dias, as plantas inoculadas com os FMA nativos apresentaram melhor desenvolvimento do que as inoculadas isoladamente com G. albida ou S. hetervgama, em todos os parâmetros avaliados, tanto em solo adubado como em solo não adubado.Due to the fast growth of papaya few are the soils that can satisfy its demand for nutrients under natural conditions, the application of mineral fertilizers that favor the plants in the period of the transplant to the field being necessary. The arbuscular mycorrhizal fungi (AMF are known for making their hosts more resistant to biotic and abiotic stress, this being the reason why they have

  13. Evaluación de la gestión de la ASADA COOPEROSALES, San Nicolás, Cartago, desde una perspectiva del uso sostenible del recurso hídrico.

    OpenAIRE

    Pino-Gómez, Macario; Soto-Córdoba, Silvia; Gaviria-Montoya, Lilliana

    2016-01-01

    Proyecto de Investigación La sostenibilidad de la distribución del agua potable en las diferentes ASADAs del país es un tema complejo, multifactorial y dependiente de muchos actores y condiciones ambientales. A la fecha los principales esfuerzos y enfoques se han orientado en los procesos de conducción del agua, tratamiento y distribución, asumiendo, que el recurso es inagotable e inalterable. Con gran preocupación ya estamos detectando como este recurso cada día es más escaso ...

  14. Is Sustainable Remediation Now a Self-Sustaining Process? an International Progress Report

    Science.gov (United States)

    Smith, J. W. N.

    2014-12-01

    Sustainable remediation - the consideration of environmental, social and economic factors associated with soil and groundwater risk-management options, to help select the best overall solution - has been a rapidly evolving topic in recent years. The first published reference[1] to 'sustainable remediation' was in the title of a 1999 conference paper by Kearney et al., (1999), but activity really accelerated in the middle-late 2000's, with establishment of a number of collaborative sustainable remediation groups and fora, and increased publication rates in the peer reviewed literature (Fig 1). Figure 1. Journal paper publications with search term 'sustainable remediation' (SCOPUS survey, 17 July 2014) This presentation will review the international progress of sustainable remediation concept development and application in regulatory and corporate decision-making processes. It will look back at what has already been achieved, provide an update on the latest initiatives and developments, and look forward to what the future of sustainable remediation might look like. Specifically it will describe: Sustainable remediation frameworks: synergies and international collaboration; Latest guidance and tools developed by the various sustainable remediation organisations (SuRFs), including the SuRF-UK Best Management Practices and Tier 1 Briefcase; Best practice standard development by ASTM and ISO; Regulatory acceptance of sustainable remediation, including incorporation into legislation, and the NICOLE - Common Forum Joint statement on 'risk-informed and sustainable remediation' in Europe; Examples of corporate adoption of sustainable remediation principles. The presentation will conclude with a look forward to a vision of sustainable remediation in 2020.

  15. Transitioning from military medics to registered nurses.

    Science.gov (United States)

    Keita, Mohamed D; Diaz, Valerie J; Miller, Audrey P; Olenick, Maria; Simon, Sharon R

    2015-01-01

    The nursing shortage in the USA is expected to reach 260,000 registered nurses (RNs) by 2025. The most profound shortages are expected in California and Florida, translating into 109,779 and 128,364 RN jobs, respectively. Despite a foreseen growth in nursing career opportunities nationwide, the supply of nurses will be insufficient to meet the corresponding demand. Capitalizing on prior education, experience, and skills of military clinical personnel to fill these jobs could significantly reduce the projected nursing shortage. Florida International University's Nicole Wertheim College of Nursing and Health Sciences is circumventing barriers to recruit, retain, and graduate transitioning veteran medics and corpsmen as Bachelor of Science in Nursing prepared RNs who reintegrate into the civilian workforce. The Veteran Bachelor of Science in Nursing (VBSN) program is in the form of a cooperative agreement between Florida International University and the US Health Resources and Services Administration. The VBSN program's main objective is to build upon the unique leadership skills, clinical education, and training of military medics and corpsmen to ensure successful completion of the Bachelor of Science in Nursing curriculum. VBSN students, as veterans themselves, have unique knowledge and exposure to the specific health issues and needs of the veteran population overall. They are poised and best prepared to effectively care for the US population, particularly the current 22 million US veterans and 1.6 million Florida veterans. Additionally, the VBSN program will alleviate the challenges, such as the lack of recognition of military skills, unemployment, the substandard income, and homelessness that many former service members face after separation from the military.

  16. Arbuscular mycorrhizal strategy for zinc mycoremediation and diminished translocation to shoots and grains in wheat

    Science.gov (United States)

    2017-01-01

    Mycoremediation is an on-site remediation strategy, which employs fungi to degrade or sequester contaminants from the environment. The present work focused on the bioremediation of soils contaminated with zinc by the use of a native mycorrhizal fungi (AM) called Funneliformis geosporum (Nicol. & Gerd.) Walker & Schüßler. Experiments were performed using Triticum aestivum L. cv. Gemmeza-10 at different concentrations of Zn (50, 100, 200 mg kg-1) and inoculated with or without F. geosporum. The results showed that the dry weight of mycorrhizal wheat increased at Zn stressed plants as compared to the non-Zn-stressed control plants. The concentrations of Zn also had an inhibitory effect on the yield of dry root and shoot of non-mycorrhizal wheat. The photosynthetic pigment fractions were significantly affected by Zn treatments and mycorrhizal inoculation, where in all treatments, the content of the photosynthetic pigment fractions decreased as the Zn concentration increased in the soil. However, the level of minerals of shoots, roots, and grains was greatly influenced by Zn-treatment and by inoculation with F. geosporum. Treatment with Zn in the soil increased Cu and Zn concentrations in the root, shoot and grains, however, other minerals (P, S, K, Ca and Fe) concentration was decreased. Inoculation of wheat with AM fungi significantly reduced the accumulation of Zn and depressed its translocation in shoots and grains of wheat. In conclusion, inoculation with a native F. geosporum-improves yields of wheat under higher levels of Zn and is possible to be applied for the improvement of zinc contaminated soil. PMID:29145471

  17. The role of G-protein receptor 84 in experimental neuropathic pain.

    Science.gov (United States)

    Nicol, Louise S C; Dawes, John M; La Russa, Federica; Didangelos, Athanasios; Clark, Anna K; Gentry, Clive; Grist, John; Davies, John B; Malcangio, Marzia; McMahon, Stephen B

    2015-06-10

    G-protein receptor 84 (GPR84) is an orphan receptor that is induced markedly in monocytes/macrophages and microglia during inflammation, but its pathophysiological function is unknown. Here, we investigate the role of GPR84 in a murine model of traumatic nerve injury. Naive GPR84 knock-out (KO) mice exhibited normal behavioral responses to acute noxious stimuli, but subsequent to partial sciatic nerve ligation (PNL), KOs did not develop mechanical or thermal hypersensitivity, in contrast to wild-type (WT) littermates. Nerve injury increased ionized calcium binding adapter molecule 1 (Iba1) and phosphorylated p38 MAPK immunoreactivity in the dorsal horn and Iba1 and cluster of differentiation 45 expression in the sciatic nerve, with no difference between genotypes. PCR array analysis revealed that Gpr84 expression was upregulated in the spinal cord and sciatic nerve of WT mice. In addition, the expression of arginase-1, a marker for anti-inflammatory macrophages, was upregulated in KO sciatic nerve. Based on this evidence, we investigated whether peripheral macrophages behave differently in the absence of GPR84. We found that lipopolysaccharide-stimulated KO macrophages exhibited attenuated expression of several proinflammatory mediators, including IL-1β, IL-6, and TNF-α. Forskolin-stimulated KO macrophages also showed greater cAMP induction, a second messenger associated with immunosuppression. In summary, our results demonstrate that GPR84 is a proinflammatory receptor that contributes to nociceptive signaling via the modulation of macrophages, whereas in its absence the response of these cells to an inflammatory insult is impaired. Copyright © 2015 Nicol et al.

  18. Wolf-Rayet Stars

    Science.gov (United States)

    Hamann, Wolf-Rainer; Sander, Andreas; Todt, Helge

    Nearly 150 years ago, the French astronomers Charles Wolf and Georges Rayet described stars with very conspicuous spectra that are dominated by bright and broad emission lines. Meanwhile termed Wolf-Rayet Stars after their discoverers, those objects turned out to represent important stages in the life of massive stars. As the first conference in a long time that was specifically dedicated to Wolf-Rayet stars, an international workshop was held in Potsdam, Germany, from 1.-5. June 2015. About 100 participants, comprising most of the leading experts in the field as well as as many young scientists, gathered for one week of extensive scientific exchange and discussions. Considerable progress has been reported throughout, e.g. on finding such stars, modeling and analyzing their spectra, understanding their evolutionary context, and studying their circumstellar nebulae. While some major questions regarding Wolf-Rayet stars still remain open 150 years after their discovery, it is clear today that these objects are not just interesting stars as such, but also keystones in the evolution of galaxies. These proceedings summarize the talks and posters presented at the Potsdam Wolf-Rayet workshop. Moreover, they also include the questions, comments, and discussions emerging after each talk, thereby giving a rare overview not only about the research, but also about the current debates and unknowns in the field. The Scientific Organizing Committee (SOC) included Alceste Bonanos (Athens), Paul Crowther (Sheffield), John Eldridge (Auckland), Wolf-Rainer Hamann (Potsdam, Chair), John Hillier (Pittsburgh), Claus Leitherer (Baltimore), Philip Massey (Flagstaff), George Meynet (Geneva), Tony Moffat (Montreal), Nicole St-Louis (Montreal), and Dany Vanbeveren (Brussels).

  19. The chromosphere above a δ-sunspot in the presence of fan-shaped jets

    Science.gov (United States)

    Robustini, Carolina; Leenaarts, Jorrit; de la Cruz Rodríguez, Jaime

    2018-01-01

    Context. Delta-sunspots are known to be favourable locations for fast and energetic events like flares and coronal mass ejections. The photosphere of this sunspot type has been thoroughly investigated in the past three decades. The atmospheric conditions in the chromosphere are not as well known, however. Aims: This study is focused on the chromosphere of a δ-sunspot that harbours a series of fan-shaped jets in its penumbra. The aim of this study is to establish the magnetic field topology and the temperature distribution in the presence of jets in the photosphere and the chromosphere. Methods: We use data from the Swedish 1m Solar Telescope (SST) and the Solar Dynamics Observatory. We invert the spectropolarimetric Fe I 6302 Å and Ca II 8542 Å data from the SST using the non-LTE inversion code NICOLE to estimate the magnetic field configuration, temperature, and velocity structure in the chromosphere. Results: A loop-like magnetic structure is observed to emerge in the penumbra of the sunspot. The jets are launched from this structure. Magnetic reconnection between this emerging field and the pre-existing vertical field is suggested by hot plasma patches on the interface between the two fields. The height at which the reconnection takes place is located between log τ500 = -2 and log τ500 = -3. The magnetic field vector and the atmospheric temperature maps show a stationary configuration during the whole observation. Movies associated to Figs. 3-5 are available at http://www.aanda.org

  20. Living with the label "disability": personal narrative as a resource for responsive and informed practice in biomedicine and bioethics.

    Science.gov (United States)

    Bishop, Jeffery; Sunderland, Naomi

    2013-01-01

    What is it like to live with the label "Disability?" NIB editorial staff and narrative symposium editors, Jeffery Bishop and Naomi Sunderland developed a call for stories, which was sent to several list serves, shared with the 1000 Voices Project community and posted on Narrative Inquiry in Bioethics' website. The request for personal stories from people who identify with the label "disabled" asked them to: consider how the label "disability" interacts with other aspects of their life in health care settings; does the term "disability" reflect their actual embodied experiences of impairment or does it fail to do justice to their particular experience of impairment; describe the kind of experiences that are possible because of the impairment(s); discuss how the label has affected their "authentic voice"; and many other concepts about what effects the label has on their lives. These authors share deeply personal experiences that will help readers understand their world, challenges, and joys. Thirteen stories are found in the print version of the journal and an additional five supplemental stories are published online only through Project MUSE. The stories are complemented by four commentary articles by Elizabeth R. Schiltz; Lorna Hallahan; Nicole Matthews, Kathleen Ellem, and Lesley Chenoweth; and Jeffery Bishop, Rachelle Barina, and Devan Stahl. These scholars come from the disciplines of law, social work, media studies, medicine, and bioethics from Australia and the United States. Together, the symposium's storytellers and commentators offer striking and informative insights into the everydayness of living with disabilities.

  1. Patterns in Patient Access and Utilization of Online Medical Records: Analysis of MyChart.

    Science.gov (United States)

    Redelmeier, Donald A; Kraus, Nicole C

    2018-02-06

    Electronic patient portals provide a new method for sharing personal medical information with individual patients. Our aim was to review utilization patterns of the largest online patient portal in Canada's largest city. We conducted a 4-year time-trend analysis of aggregated anonymous utilization data of the MyChart patient portal at Sunnybrook Health Sciences Centre in Ontario, Canada, from January 1, 2012, through December 31, 2015. Prespecified analyses examined trends related to day (weekend vs weekday), season (July vs January), year (2012 vs 2015), and an extreme adverse weather event (ice storm of December 20-26, 2013). Primary endpoints included three measures of patient portal activity: registrations, logins, and pageviews. We identified 32,325 patients who registered for a MyChart account during the study interval. Time-trend analysis showed no sign of attenuating registrations over time. Logins were frequent, averaged 734 total per day, and showed an increasing trend over time. Pageviews mirrored logins, averaged about 3029 total per day, and equated to about 5 pageviews during the average login. The most popular pageviews were clinical notes, followed by laboratory results and medical imaging reports. All measures of patient activity were lower on weekends compared to weekdays (Psecurity breach, malware attack, or software failure occurred during the study. Online patient portals can provide a popular and reliable system for distributing personal medical information to active patients and may merit consideration for hospitals. ©Donald A Redelmeier, Nicole C Kraus. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 06.02.2018.

  2. Adenopatía leishmaniásica

    Directory of Open Access Journals (Sweden)

    Gerzaín Rodríguez Toro

    1986-06-01

    Full Text Available Presentamos un paciente de 12 años de edad de la Vereda de San Nicolás en Quipile (Cundinamarca, que consultó por presentar una masa inguinal izquierda de 8 x 5 cm. En el examen físico se descubrió una úlcera de aspecto leishmaniásico en el tercio inferior de la misma pierna. La biopsia cutánea se extravió y la resección de la masa inguinal mostró ganglios linfáticos con granulomas sugestivos de sarcoidosis. La correlación clínico-patológica y epidemiológica permitió diagnosticar y tratar el paciente como leishmaniasis cutánea con curación rápida de su úlcera y de la masa inguinal remanente. Retrospectivamente se demostraron amastigotes en la revisión de los cortes del ganglio y en el tejido ganlionar incluído para microscopía electrónica. Con anticuerpos monoclonales anti-amastigotes de leishmania se demostraron escasos parásitos fagocitados en los macrófagos de los granulomas del ganglio. La adenopatía leishmaniásica puede ser el motivo inicial de consulta del paciente y debe tenerse en cuenta entre las inflamaciones granulomatosas del ganglio linfático. Mediante criterios clínicos, epidemiológicos, parasitológicos, histopatológicos e inmunológicos se debe determinar si la adenopatía corresponde a leishmaniasis visceral o a otra forma de leishmaniasis.

  3. Activation of endogenous opioid gene expression in human keratinocytes and fibroblasts by pulsed radiofrequency energy fields

    Directory of Open Access Journals (Sweden)

    Moffett J

    2012-09-01

    Full Text Available John Moffett,1 Linley M Fray,1 Nicole J Kubat21Life Science Department, 2Independent Consultant, Regenesis Biomedical Inc, Scottsdale, AZ, USABackground: Pulsed radiofrequency energy (PRFE fields are being used increasingly for the treatment of pain arising from dermal trauma. However, despite their increased use, little is known about the biological and molecular mechanism(s responsible for PRFE-mediated analgesia. In general, current therapeutics used for analgesia target either endogenous factors involved in inflammation, or act on endogenous opioid pathways.Methods and Results: Using cultured human dermal fibroblasts (HDF and human epidermal keratinocytes (HEK, we investigated the effect of PRFE treatment on factors, which are involved in modulating peripheral analgesia in vivo. We found that PRFE treatment did not inhibit cyclooxygenase enzyme activity, but instead had a positive effect on levels of endogenous opioid precursor mRNA (proenkephalin, pro-opiomelanocortin, prodynorphin and corresponding opioid peptide. In HEK cells, increases in opioid mRNA were dependent, at least in part, on endothelin-1. In HDF cells, additional pathways also appear to be involved. PRFE treatment was also followed by changes in endogenous expression of several cytokines, including increased levels of interleukin-10 mRNA and decreased levels of interleukin-1β mRNA in both cell types.Conclusion: These findings provide a new insight into the molecular mechanism underlying PRFE-mediated analgesia reported in the clinical setting.Keywords: peripheral analgesia, endogenous opioids, endothelin-1, endothelin receptor A, endothelin receptor B, pulsed radiofrequency energy field, cyclooxygenase

  4. Update on ranolazine in the management of angina

    Directory of Open Access Journals (Sweden)

    Codolosa JN

    2014-06-01

    Full Text Available J Nicolás Codolosa,1 Subroto Acharjee,1 Vincent M Figueredo1,2 1Einstein Center for Heart and Vascular Health, Einstein Medical Center, 2Jefferson Medical College, Philadelphia, PA, USA Abstract: Mortality rates attributable to coronary heart disease have declined in recent years, possibly related to changes in clinical presentation patterns and use of proven secondary prevention strategies. Chronic stable angina (CSA remains prevalent, and the goal of treatment is control of symptoms and reduction in cardiovascular events. Ranolazine is a selective inhibitor of the late sodium current in myocytes with anti-ischemic and metabolic properties. It was approved by the US Food and Drug Administration in 2006 for use in patients with CSA. Multiple, randomized, placebo-controlled trials have shown that ranolazine improves functional capacity and decreases anginal episodes in CSA patients, despite a lack of a significant hemodynamic effect. Ranolazine did not improve cardiovascular mortality or affect incidence of myocardial infarction in the MERLIN (Metabolic Efficiency with Ranolazine for Less Ischemia in Non-ST-Elevation Acute Coronary Syndrome-TIMI (Thrombolysis In Myocardial Infarction 36 trial, but significantly decreased the incidence of recurrent angina. More recently, ranolazine has been shown to have beneficial and potent antiarrhythmic effects, both on supraventricular and ventricular tachyarrhythmias, largely due to its inhibition of the late sodium current. Randomized controlled trials testing these effects are underway. Lastly, ranolazine appears to be cost-effective due to its ability to decrease angina-related hospitalizations and improve quality of life. Keywords: ranolazine, chronic stable angina, coronary artery disease

  5. Learning about the game: designing science games for a generation of gamers

    Science.gov (United States)

    Chmiel, Marjee

    2012-12-01

    This paper is a response to "Challenges and Opportunities: Using a science-based video game in secondary school settings" by Rachel Muehrer, Jennifer Jenson, Jeremy Friedberg, and Nicole Husain. The article highlights two critical areas that I argue require more research in the studies of video games in education. The first area focuses on the need to better understand how children interact with non-educational games, outside of the school setting. This includes issues such as "gamer culture" and game play styles. The better we understand these issues, the better educational game designers and implementers can imagine the kinds of behaviors that might be elicited from students when we bring educational games into their classroom. In this focus, the student is the unit of analysis, but it is the student in and out of the classroom: the way the student understands video games when she is at home, playing with friends, and at school. The second area focuses on the study of the classroom as a unit of analysis. As the authors of this study reveal, classroom cultures affect the reception and success of an educational game. This is to ask, how does a game play when students have to play it in pairs or groups for a lack of resources? What is the role of the teacher in the success of video game implementation? How does a game react to multiple server requests in a short period of time? These are issues that are still largely unexplored in the educational game design literature.

  6. The Historical Foundations. Historical Architectural Treaty How Information Source of the Architectonic Heritage

    Directory of Open Access Journals (Sweden)

    Fernando Da Casa

    2011-12-01

    Full Text Available In order to address architectural heritage conservation, we must be familiar with the medium with which we will be working, its function and response to incidents or external actions (natural or anthropogenic and how the buildings were conceived and constructed in order to understand how they will be affected by the intervention process to which they will be subjected and adopt the adequate measures so these processes will not harm the buildings. An important element is the foundation. This is a fundamental, yet often forgotten, element. It is important to know the history of the foundations, how and why they were constructed and for this, it is essential to study architectural treatises as the origin of their design. It is surprising to read classical architecture treatises and observe that they do not refer to calculations of dimensions, but to constructive solutions that today may seem clever because they are obvious, but in reality, they do not address the thoughts of the designer or builder. The historic architectural treatises on construction that significantly influenced Spanish construction, which we studied and will present in this article, include Vitruvius and Palladio as well as the developments in the eighteenth and nineteenth centuries, and even into the first half of the twentieth century: (Vitruvius (1st century BC, Palladio (1524, Alberti (1582, Cristóbal de Rojas (1598, Fray Laurencio San Nicolás (1639, Brizguz y Bru (1738, Rieger (1763, Fornes y Gurrea (1841, Espinosa (1859, Marcos y Bausá (1879, Ger y Lobez (1898 and Barberot (1927.

  7. Evaluación de la incidencia del Virus de la marchitez moteada del tomate (TSWV en arvenses asociadas al cultivo de crisantemo en el Valle de San Nicolás

    Directory of Open Access Journals (Sweden)

    Elizabeth Castro

    2017-08-01

    Full Text Available Para la región del Oriente antioqueño el cultivo de crisantemo es una importante fuente de empleo y motor de desarrollo, una limitante de la producción de este cultivo es la enfermedad causada por TSWV. En un programa de manejo integrado de enfermedades se busca identificar y detener la entrada y dispersión del patógeno dentro del cultivo; en el caso del patosistema TSWV-Crisantemo, una puerta de entrada importante pueden ser las arvenses aledañas a los bloques de producción, ya que permiten la propagación del vector (trips y sirven de reservorio para la enfermedad. Es por esto que este trabajo tuvo como objetivos: identificar las especies de arvenses adyacentes a los cultivos de crisantemo del Oriente antioqueño, evaluar la incidencia de TSWV en ellas y determinar las especies de trips presentes en las arvenses más frecuentemente encontradas. Se colectaron 360 plantas en 6 fincas productoras de Crisantemo de la región, se clasificaron taxonómicamente y se encontraron 34 especies dentro de 19 familias botánicas de las cuales las especies encontradas con mayor frecuencia fueron: Galinsoga quadriradiata, Cardamine hirsuta, Oxalis latifolia, Amaranthus viridis, Senecio vulgaris y Polygonum nepalense. Se realizó prueba DAS-ELISA para la detección de TSWV a las 34 especies y se encontró que solo una arvense fue positiva, Portulaca oleracea; en un muestreo posterior se evaluaron otras 20 plantas por RT-PCR de las más frecuentes que se encontraron y en este segundo grupo no fue detectada ninguna planta infectada por TSWV. Los trips encontrados en las especies de arvenses evaluadas pertenecen al género Frankliniella sp., especies: F. occidentallis y F. panamensis. En este trabajo se observó una mayor captura de insectos en crisantemo que en las arvenses acompañantes, lo que sugiere su mayor preferencia por el cultivo y explicaría la baja transmisión de TSWV observada en las plantas arvenses.

  8. Imagining Geographies, Mapping Identities

    Directory of Open Access Journals (Sweden)

    Matthew Graves

    2015-03-01

    University, “The Perils of Proximity: The Geopolitical Underpinnings of Australian views of New Caledonia in the 19th Century." - Annie Ousset-Krief (Paris III, "Le Yiddishland newyorkais." - Carolyn Stott (Sydney University, "Belleville: Space, Place and Identity." - Esme Cleall (University of Sheffield, "Silencing Deafness: Marginalising Disability in the 19th century."

  9. Oltar Sv. Jeronima u crkvi Sv. Šime u Zadru i radionica Bettamelli

    Directory of Open Access Journals (Sweden)

    Bojan Goja

    2012-12-01

    Full Text Available U radu se na temelju arhivskih podataka govori o oltaru Sv. Jeronima u crkvi Sv. Šime u Zadru. Od ranije se zna da je oltar dala podići i o njegovu se uređenju brinula bratovština hrvatskih i albanskih vojnika (Croatti a cavallo i Soldati Albanesi u službi Mletačke Republike, osnovana 1675. godine u Zadru. Novim je arhivskim istraživanjima utvrđeno da je dana 26. rujna 1694. godine bratovština odobrila izdatak u iznosu od 200 srebrnih dukata, namijenjenih venecijanskim klesarima braći Bettamelli kao predujam za izradu oltara te da su radovi na njegovu podizanju započeti u travnju 1696. godine. Na temelju zapisa o gradnji oltara iznijeta je pretpostavka da se grb na istočnom pilastru stipesa oltara, ranije povezivan s predstavnicima obitelji Civran, odnosi na zadarskog plemića i istaknutog zapovjednika u mletačkoj vojsci, Šimuna Fanfognu (Zadar, 7. travnja 1663. - Lendinara, 6. ožujka 1707. koji je obavljao i dužnost prokuratora oltara. Brojni radovi na uređenju oltara i kapele Sv. Jeronima obavljani su i tijekom čitavog 18. stoljeća, a na njima su bili uposleni brojni mjesni majstori različitih struka: graditelji Antonio Piovesana (1742. i Antonio Bernardini (1789., oltarist Girolamo Picco (1756., marangon Domenico Tomaselli (1743., kovač Antonelli (1744. te zlatari Zorzi Cullisich (1738., Nicolò Giurovich (1752. i Giuseppe Rado (1755.. Donose se još neke zanimljivosti vezane uz uređenje oltara i djelovanje bratovštine Sv. Jeronima.

  10. Types and delivery of emotional support to promote linkage and engagement in HIV care

    Directory of Open Access Journals (Sweden)

    Cook CL

    2017-12-01

    Full Text Available Christa L Cook,1 Shantrel Canidate,2 Nicole Ennis,3 Robert L Cook4 1Department of Family, Community, and Health System Science, College of Nursing, 2Social and Behavioral Science, College of Public Health and Health Profession, 3Department of Clinical and Health Psychology, College of Public Health and Health Professions, 4Department of Epidemiology, College of Public Health and Health Professions and College of Medicine, University of Florida, Gainesville, FL, USA Purpose: Despite recommendations for early entry into human immunodeficiency virus (HIV care, many people diagnosed with HIV delay seeking care. Multiple types of social support (ie, cognitive, emotional, and tangible are often needed for someone to transition into HIV care, but a lack of emotional support at diagnosis may be the reason why some people fail to stay engaged in care. Thus, the purpose of this study was to identify how people living with HIV conceptualized emotional support needs and delivery at diagnosis. Method: We conducted a secondary analysis of qualitative data from 27 people living with HIV, many of whom delayed entry into HIV care. Results: Participants described their experiences seeking care after an HIV diagnosis and identified components of emotional support that aided entry into care – identification, connection, and navigational presence. Many participants stated that these types of support were ideally delivered by peers with HIV. Conclusion: In clinical practice, providers often use an HIV diagnosis as an opportunity to educate patients about HIV prevention and access to services. However, this type of social support may not facilitate engagement in care if emotional support needs are not met. Keywords: linkage to care, engagement in care, social support, qualitative

  11. Female sexual dysfunction: a focus on flibanserin

    Directory of Open Access Journals (Sweden)

    Lodise NM

    2017-10-01

    Full Text Available Nicole M Lodise Department of Pharmacy Practice, Albany College of Pharmacy and Health Sciences, Albany, NY, USA Abstract: Flibanserin is the first US Food and Drug Administration (FDA-approved option for sexual dysfunction, specifically low sexual desire. Until recently, there were no FDA-approved medication options to assist the ~40% of women affected by female sexual dysfunction (FSD. Often, patients report feeling uncomfortable discussing sexual health, identifying a strong need for health care professionals (HCPs to proactively reach out to patients to identify concerns and initiate a discussion about sexual health and the available treatment options. Within the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DMS-5, the criteria of female sexual interest/arousal disorder (FSIAD are outlined, encompassing one of the most common sexual concerns, formerly in its own category defined as hypoactive sexual desire disorder (HSDD or low sexual desire. HSDD is the absence or deficiency of sexual interest and/or desire leading to significant distress and interpersonal difficulties. HCPs offer an important service in assessing their patients and providing information about treatment considerations while ensuring patient comfort with this topic. This article provides an overview of the types and potential causes associated with FSD and the role of flibanserin in practice as a treatment option. Despite a need for additional study in diverse populations, flibanserin has demonstrated efficacy with increased female sexual function index (FSFI total and desire domain scores in clinical studies indicating benefit in sexual desire. Common patient or provider-administered assessment tools to assist in identifying affected patients and patient counseling strategies are reviewed. Keywords: female sexual dysfunction, low sexual desire, hypoactive sexual desire disorder, pharmacotherapy, flibanserin

  12. Discurso de Posesión del Académico José Félix Patiño Restrepo.

    Directory of Open Access Journals (Sweden)

    Victoria Rodriguez

    1998-08-01

    fervor, a su dedicación y a su lealtad con los mejores intereses de la profesión.

    Significativo es que la Academia se reúna hoy en esta sede de sobria elegancia. Representa el esfuerzo y la mística, principalmente de los anteriores presidentes, muy especialmente de Jorge Cavelier Gaviria y de Efraím Otero Ruiz, Juan Jacobo Muñoz y Gilberto Rueda, con el apoyo de todos los académicos y en especial de nuestro admirado Secretario Perpetuo, el profesor César Augusto Pantoja, cuya figura tutelar preside este salón.

    En este severo recinto de la Academia Nacional de Medicina se mantiene además viva la memoria de las figuras que hicieron historia en la medicina colombiana.

    Esta noche deseo evocar dos de ellas: la de Nicolás Osorio Ricaurte, hijo del prócer Alejandro Osorio Uribe. Nicolás Osorio fue uno de los seis fundadores, en 1873, de la Sociedad de Medicina y Ciencias Naturales, hoy Academia Nacional de Medicina, y quien trajo al país en el siglo pasado un enorme bagaje de conocimientos adquiridos en la Universidad de París (La Sorbona, donde obtuvo su grado de médico con su amigo y condiscípulo Georges Clemenceau...


  13. EXPOSICIÓN TEMPORAL. ALGUNOS DE LOS PRIMEROS LIBROS MÉDICOS ESCRITOS POR COLOMBIANOS ENTRE 1820-1920.

    Directory of Open Access Journals (Sweden)

    Hugo Armando Sotomayor Tribin

    2015-12-01

    Full Text Available

    Sexta muestra de la serie “Objetos del trimestre”, que busca mostrar diferentes objetos, fotografías, libros, y documentos del Museo de Historia de la Medicina de la Academia.

    INTRODUCCIÓN

    En la Nueva Granada de principios del siglo XIX solo existía una facultad o escuela de medicina, la del Colegio Mayor de Nuestra Señora del Rosario, en Bogotá. A partir de 1828 ya existían, en lo que hoy es Colombia, la Escuela de Medicina de la Universidad Central, la escuela de Medicina del Magdalena y el Istmo asentada en Cartagena, y sobrevivían las cátedras de medicina del Rosario y San Bartolomé, con sede en Bogotá; en 1864 se abrió en Bogotá la primera Escuela de Medicina, privada; en esa década de los sesenta del siglo XIX el Estado Soberano del Cauca reanudó y cerró los estudios de medicina en el Colegio del Estado, el Estado Soberano de Boyacá activó en 1869 en el Colegio de Boyacá la cátedra de medicina, de vida breve. A finales del siglo XIX solo existían las facultades de medicina de las universidades Nacional, de Antioquia y de Cartagena, y en 1920 el país seguía teniendo esas tres facultades de medicina en funcionamiento.

    Aunque se logró tener conocimiento de catorce libros, solo se exhiben 10 (uno por autor, a excepción de Nicolás Osorio y Ricaurte con dos, ambos exhibidos, y Luis Cuervo Márquez con dos, solo uno exhibido, con la ausencia de las obras de los autores Ricardo de La Parra, Juan de Dios Tavera Barriga y Gabriel D. Ujueta y el libro de Luis Cuervo Márquez titulado: La fiebre amarilla en el interior de Colombia.

    Sobre el total de los 14 libros, diez están exhibidos y de ellos, tres fueron publicados en lo que iba hasta ese momento del siglo XX: Manual de Higiene y Medicina Infantil, de Barberi; Contribución al estudio de la lepra en Colombia, de Montoya y Flórez, y Geografía Médica y patológica de Colom- bia: contribución al

  14. Presión e intereses en torno al cargo de protector general de indios del Nuevo Reino de León: el caso de Nicolás de Villalobos, 1714-1734

    Directory of Open Access Journals (Sweden)

    Baeza Martín, Ascensión

    2010-06-01

    Full Text Available The pernicious transformation undergone by the system of use of the indigenous workpeople in the Nuevo Reino de Leon, characterized by the ravages and slavery to the Indians in the encomiendas or congregas, provoked their rebelliousness. The frequent assaults to the Spanish colonists and their properties, as well as the expeditions and punishments of these against the natives reflected the hard conditions of life in that province of the northeast of the Viceroyalty of Nueva España and the constant been military of the same one. With the substantial changes implanted from the viceregal government by means of the shipment in 1714 of the commissioner Francisco de Barbadillo Victoria and the creation by this one of the employment of General Indians Protector in that earth, one was to restrain this uncontrollable situation. The difficulty of which the figure of the protector, so necessary in the first times of the reforms, held fast, would let see the partisanship, passions and interests of the authorities and the diverse social sectors of that border region.

    La perniciosa transformación sufrida por el sistema de utilización de la mano de obra indígena en el Nuevo Reino de León, caracterizado por los estragos y esclavitud a los indios en las encomiendas o congregas, provocaban su rebeldía. Los frecuentes asaltos a los colonos españoles y sus propiedades, así como las expediciones y castigos de estos contra los aborígenes reflejaban las duras condiciones de vida en esa provincia del nordeste del Virreinato de Nueva España y el constante estado de guerra de la misma. Con los substanciales cambios implantados desde el gobierno virreinal mediante el envío en 1714 del comisionado Francisco de Barbadillo Victoria y la creación por éste del cargo de protector general de indios en esa tierra, se trató de frenar esta incontrolable situación. La dificultad de que se afianzara la figura del protector, tan necesaria en los primeros tiempos de las reformas, dejaría ver los partidismos, pasiones e intereses de las autoridades y de los diversos sectores sociales de esa región fronteriza.

  15. The application of isotopic (32P and 15N) dilution techniques to evaluate the interactive effect of phosphate-solubilizing rhizobacteria, mycorrhizal fungi and Rhizobium to improve the agronomic efficiency of rock phosphate for legume crops

    International Nuclear Information System (INIS)

    Barea, J.M.; Toro, M.; Azcon, R.; Orozco, M.O.; Campos, E.; Azcon, R.

    2002-01-01

    A pot experiment was designed to evaluate the interactive effects of multifunctional microbial inoculation treatments and rock phosphate (RP) application on N and P uptake by alfalfa through the use of 15 N and 32 P isotopic dilution approaches. The microbial inocula consisted of a wild type (WT) Rhizobium meliloti strain, the arbuscular mycorrhizal (AM) fungus Glomus mosseae (Nicol. and Gerd.) Gerd. and Trappe, and a phosphate solubilizing rhizobacterium (Enterobacter sp.). Inoculated microorganisms were established in the root tissues and/or in the rhizosphere soil of alfalfa plants (Medicago sativa L.). Improvements in N and P accumulation in alfalfa corroborate beneficial effects of Rhizobium and AM interactions. Inoculation with selected rhizobacteria improved the AM effect on N or P accumulation in both the RP-added soil and in the non RP-amended controls. Measurements of the 15 N/ 14 N ratio in plant shoots indicate an enhancement of the N 2 fixation rates in Rhizobium-inoculated AM-plants, over that achieved by Rhizobium in non-mycorrhizal plants. Whether or not RP was added, AM-inoculated plants showed a lower specific activity ( 32 P/ 31 P) than did their comparable non-mycorrhizal controls, suggesting that the plant was using otherwise unavailable P sources. The phosphate-solubilizing, AM-associated, microbiota could in fact release phosphate ions, either from the added RP or from the indigenous 'less-available' soil phosphate. A low Ca concentrations in the test soil may have benefited P solubilization. Under field conditions, the inoculation with AM fungi significantly increased plant biomass and N and P accumulation in plant tissues. Phosphate-solubilizing rhizobacteria improved mycorrhizal responses in soil dually receiving RP and organic matter amendments. Organic matter addition favoured RP solubilization. This, together with a tailored microbial inoculation, increased the agronomic efficiency of RP in the test soil that was Ca deficient at neutral

  16. Recent legalization of cannabis use: effects on sleep, health, and workplace safety

    Directory of Open Access Journals (Sweden)

    Bowles NP

    2017-10-01

    Full Text Available Nicole P Bowles, Maya X Herzig, Steven A Shea Oregon Institute of Occupational Health Sciences, Oregon Health & Science University, Portland, OR, USAThe recent legalization of cannabis for medical and recreational use in many states in the United States and internationally4,5 has resulted in a decrease in stigma and of perceived risk of cannabis use, more frequent use of cannabis, use of higher potency cannabis products, and increased dependence on cannabis use.6–8 Cannabis sativa and its derivatives are often used for improved sleep and relaxation; characteristics originally attributed to Indian hemp in the nineteenth century.1–3 Cannabis alters the sleep–wake cycle, increases the production of melatonin, and can inhibit the arousal system by activating cannabinoid type 1 (CB1 receptors in the basal forebrain and other wakepromoting centers.9–12 Investigations have shown that the major psychoactive compound in cannabis, Δ9-tetrahydrocannabinol (THC, can decrease sleep onset latency in naïve users or at low doses in experienced users (eg, 70 mg/day; however, higher doses in experienced users increased sleep latency and wake after sleep onset.9,13,14 Indeed, frequent cannabis users (≥5 uses/week for 3 months and lifetime use ≥2 years are reported to have shorter total sleep duration, less slow wave sleep, worse sleep efficiency, and longer sleep onset compared to controls.15 The contrasting benefits of THC exposure may represent the biphasic influence of THC on CB1 receptors whereby acute use causes more activation of CB1 receptors and tendency toward sleep, but long-term use results in desensitization of the CB1 receptor and decreased downstream signaling.

  17. Sordera, tragedia y muerte de Ludwig van Beethoven

    Directory of Open Access Journals (Sweden)

    Darío Morón Díaz

    2008-07-01

    Full Text Available

    La sordera de Ludwig van Beethoven fue atribuida a distintas enfermedades: a una neuritis
    acústica debido a la fiebre tifoidea, a la sífilis, a la hepatitis, a una colitis, al reumatismo, a abscesos,
    a una criopatia debida al frío y a la osificación del tejido cartilaginoso que conduce al oído ínterno,
    también mencionaron la sarcoidosis.
    Dos hechos fueron fundamentales para desechar tales especulaciones: el primero, la decisión del
    joven Ferdinand Hiller, que el 27 de marzo de 1827 cortó un mechón de cabello del cadáver de Ludwig
    van Beethoven. El segundo, el avance científico de la medicina moderna. Ambos acontecimientos han
    permitido profundizar con certeza en la etiología u origen de la sordera de Beethoven y la variada síntomatología que sufrió el genio musical.

    Esbozo biográfico
    EL 16 de diciembre de 1770, en Bonn, nació Ludwig van Beethoven, hijo de Johann Beethoven y
    Maria Magdalena Keverich; el matrimonio tuvo siete hijos, cuatro fallecieron siendo niños y tres sobrevivieron: Ludwig, Kaspar Antón Karl y Nicolás Johann.
    El padre de Beethoven fue dipsómano, debido a los excesos alcohólicos y en medio de los escándalos el
    padre agredía al niño. Deambulaba entre la Iglesia y la taberna. María Magdalena por el contrario era tierna y afectuosa con su hijo, situación que por contraste servía de refugio a Ludwig.

  18. Il Sapore della storia. Maquiavelo y los clásicos en “El príncipe” y en los “Discursos sobre la década de Tito Livio”

    Directory of Open Access Journals (Sweden)

    Jorge del PALACIO

    2012-12-01

    Full Text Available El presente trabajo analiza el papel de los clásicos en las dos principales obrasde pensamiento político de Nicolás Maquiavelo: El Príncipe y los Discursossobre la primera década de Tito Livio. En este artículo se va a sostener que elvalor que Maquiavelo otorga a los clásicos en su obra está vinculado a la ideade experiencia como fuente principal del conocimiento político. Para ello elartículo se dividirá en tres partes. En primer lugar se presentará la importanciade los clásicos en la composición de El Príncipe y los Discursos. En segundolugar se analizará la idea de la política sobre la que descansa la importanciaque Maquiavelo concede a los clásicos. En tercer y último lugar se analizará larelevancia del estudio de los clásicos en la formación humanística deMaquiavelo.The present work analyzes the role played by classical thinkers in the two chiefpolitical works of Nicholas Machiavelli: The Prince and the Discourses on Livy. Ishall maintain that the value which Machiavelli awards classical thinkers in hiswork is related to the idea that experience is the most important source ofpolitical knowledge. To this end, the essay shall be divided into three parts. Tobegin with, I shall explain the importance of classical thought in the compositionof the Prince and the Discourses. Secondly, I shall elucidate the idea of politicson the basis of which rests the importance of the classics for Machiavelli. Andfinally, I shall explain the way in which the study of the classics was essential toMachiavelli's humanistic education.

  19. Efficacy of two-month treatment with Xiloial® eyedrops for discomfort from disposable soft contact lenses

    Directory of Open Access Journals (Sweden)

    Piera Versura

    2010-09-01

    Full Text Available Piera Versura, Vincenzo Profazio, Nicole Balducci, Emilio C CamposOphthalmology Unit, Alma Mater Studiorum University of Bologna, Bologna, ItalyPurpose: To evaluate the efficacy and tolerability of Xiloial® monodose eyedrops in the treatment of patients suffering from subjective symptoms of discomfort related to disposable soft contact lens (dSCL wear.Methods: Fifteen (12 female, three male, medium age 39 ± 9 years dSCL wearers were enrolled. Inclusion criteria were Ocular Surface Disease Index (ODSI symptom questionnaire score >12, tear film break-up time (TFBUT <10 sec, Schirmer test I >10 mm over five minutes, mild punctuate keratopathy, and conjunctival staining (Oxford grading ≤4. Monodose Xiloial eyedrops were administered three times daily for a two-month period. Patients were evaluated at enrollment, after three days of washout (baseline, and after one and two months of treatment, by OSDI score, Schirmer test I, TFBUT, ferning test, ocular surface damage (Oxford grade, and serum albumin in tears (index of passive exudation related to serum leakage.Results: At endpoint versus baseline, respectively, the mean ± standard deviation of all variables improved as follows: OSDI (8.5 ± 3 versus 20.2 ± 1.6; TFBUT (9.6 ± 1.1 versus 7.1 ± 1.0; Oxford grading (0.5 ± 0.1 versus 3.6 ± 0.8; ferning test (2 ± 1 versus 2.4 ± 0.5; and Schirmer test I (14.6 ± 1.1 versus 12 ± 2.1, with P < 0.05 for all variables (Friedman and Wilcoxon tests. Tolerability was high, with no adverse events noted.Conclusions: A two-month treatment with Xiloial showed good tolerance and appeared to reduce ocular surface damage and symptoms of discomfort.Keywords: discomfort, dry eye, disposable contact lens, biopolymer tamarind seed polysaccharide–hyaluronic acid

  20. The eXtraordinarY Kids Clinic: an interdisciplinary model of care for children and adolescents with sex chromosome aneuploidy

    Directory of Open Access Journals (Sweden)

    Tartaglia N

    2015-07-01

    Full Text Available Nicole Tartaglia,1,2 Susan Howell,1,2 Rebecca Wilson,2 Jennifer Janusz,1,2 Richard Boada,1,2 Sydney Martin,2 Jacqueline B Frazier,2 Michelle Pfeiffer,2 Karen Regan,2 Sarah McSwegin,2 Philip Zeitler1,2 1Department of Pediatrics, University of Colorado School of Medicine, 2Child Development Unit, Children's Hospital Colorado, Aurora, CO, USA Purpose: Individuals with sex chromosome aneuploidies (SCAs are born with an atypical number of X and/or Y chromosomes, and present with a range of medical, developmental, educational, behavioral, and psychological concerns. Rates of SCA diagnoses in infants and children are increasing, and there is a need for specialized interdisciplinary care to address associated risks. The eXtraordinarY Kids Clinic was established to provide comprehensive and experienced care for children and adolescents with SCA, with an interdisciplinary team composed of developmental–behavioral pediatrics, endocrinology, genetic counseling, child psychology, pediatric neuropsychology, speech–language pathology, occupational therapy, nursing, and social work. The clinic model includes an interdisciplinary approach to care, where assessment results by each discipline are integrated to develop unified diagnostic impressions and treatment plans individualized for each patient. Additional objectives of the eXtraordinarY Kids Clinic program include prenatal genetic counseling, research, education, family support, and advocacy. Methods: Satisfaction surveys were distributed to 496 patients, and responses were received from 168 unique patients. Results: Satisfaction with the overall clinic visit was ranked as “very satisfied” in 85%, and as “satisfied” in another 9.8%. Results further demonstrate specific benefits from the clinic experience, the importance of a knowledgeable clinic coordinator, and support the need for similar clinics across the country. Three case examples of the interdisciplinary approach to assessment and

  1. Pío del Río Hortega and the discovery of the oligodendrocytes

    Directory of Open Access Journals (Sweden)

    Fernando ePérez-Cerdá

    2015-07-01

    Full Text Available Pío del Río Hortega (1882-1945 discovered microglia and oligodendrocytes and was after Ramón y Cajal, the most prominent figure of the Spanish school of neurology. He began his scientific career with Nicolás Achúcarro with whom he learned the use of metallic impregnation techniques suitable to study non neuronal cells. Later on, he joined Cajal´s laboratory, and afterwards he created his own group where he continued developing other innovative modifications of the silver staining methods that revolutionised the study of glial cells a century ago. He was at that time also interested in neuropathology and became a leading authority in Central Nervous System (CNS tumours. In parallel to this clinical activity, del Río Hortega rendered the first systematic description of the great polymorphism present in a subtype of macroglial cells that he named himself as oligodendroglia and later oligodendrocytes. He established their ectodermic origin and suggested that they build the myelin sheath of CNS axons, just as Schwann cells do in the periphery. Notably, he also suggested the trophic role of oligodendrocytes for neuronal functionality, an idea that it has been substantiated in the last few years. Del Río Hortega became internationally recognized and established an important neurohistological school with outstanding pupils from Spain and abroad, which nearly disappeared after his exile due to the Spanish civil war. Yet, the difficulty of metal impregnation methods and their variability in results, delayed for some decades the confirmation of his great insights into oligodendrocyte biology until the development of electron microscopy and immunohistochemistry. This review aims at summarizing the pioneer and essential contributions of del Río Hortega to the current knowledge of oligodendrocyte structure and function, and to provide a hint of the scientific personality of this extraordinary and insufficiently recognized man.

  2. Building shared situational awareness in surgery through distributed dialog

    Directory of Open Access Journals (Sweden)

    Gillespie BM

    2013-03-01

    Full Text Available Brigid M Gillespie,1 Karleen Gwinner,2 Nicole Fairweather,3 Wendy Chaboyer41NHMRC Research Centre for Clinical Excellence in Nursing Interventions for Hospitalised Patients (NCREN and Research Centre for Clinical and Community Practice Innovation (RCCCPI, Griffith Health Institute, Griffith University, Queensland, 2Griffith Centre for Cultural Research, Griffith University, Queensland, 3Department of Anaesthesiology, Princess Alexandra Hospital, Queensland, Australia, 4Excellence in Nursing Interventions for Hospitalized Patients (NCREN Research Centre for Clinical and Community Practice INHMRC Centre of Research Innovation (RCCCPI, Griffith Health Institute, Griffith University Queensland, AustraliaBackground: Failure to convey time-critical information to team members during surgery diminishes members' perception of the dynamic information relevant to their task, and compromises shared situational awareness. This research reports the dialog around clinical decisions made by team members in the time-pressured and high-risk context of surgery, and the impact of these communications on shared situational awareness.Methods: Fieldwork methods were used to capture the dynamic integration of individual and situational elements in surgery that provided the backdrop for clinical decisions. Nineteen semistructured interviews were performed with 24 participants from anesthesia, surgery, and nursing in the operating rooms of a large metropolitan hospital in Queensland, Australia. Thematic analysis was used.Results: The domain "coordinating decisions in surgery" was generated from textual data. Within this domain, three themes illustrated the dialog of clinical decisions, ie, synchronizing and strategizing actions, sharing local knowledge, and planning contingency decisions based on priority.Conclusion: Strategies used to convey decisions that enhanced shared situational awareness included the use of "self-talk", closed-loop communications, and

  3. Corneal ectasia after myopic laser in situ keratomileusis: a long-term study

    Directory of Open Access Journals (Sweden)

    Spadea L

    2012-11-01

    Full Text Available Leopoldo Spadea,1 Emilia Cantera,2 Magdalena Cortes,2 Nicole Evangelista Conocchia,1 Charles WM Stewart11University of L’Aquila, Department of Biotechnological and Applied Clinical Sciences, Eye Clinic, L’Aquila, 2Villa Stuart Clinic, Department of Ophthalmic Sciences, Rome, ItalyBackground: The purpose of this study was to evaluate the long-term postoperative incidence of and key factors in the genesis of corneal ectasia after myopic laser-assisted in situ keratomileusis (LASIK in a large number of cases.Methods: A retrospective review of one surgeon's myopic LASIK database was performed. Patients were stratified into two groups based on date of surgery, ie, group 1 (1313 eyes from 1999 to 2001 and group 2 (2714 eyes from 2001 to 2003. Visual acuity, refraction, pachymetry, and corneal topography data were available for each patient from examinations performed both before and after the refractive procedures.Results: Of the 4027 surgically treated eyes, 23 (0.57% developed keratectasia during the follow-up period, which was a minimum seven years; nine eyes (0.69% were from group 1 and 14 eyes (0.51% were from group 2. The onset of corneal ectasia was at 2.57 ± 1.04 (range 1–4 years and 2.64 ± 1.29 (range 0.5–5 years, respectively, for groups 1 and 2. The most important preoperative risk factors using the Randleman Ectasia Risk Score System were manifest refractive spherical error in group 1 and a thin residual stromal bed in group 2. Each of the cases that developed corneal ectasia had risk factors that were identified.Conclusion: Ectasia was an uncommon outcome after an otherwise uncomplicated laser in situ keratomileusis procedure. The variables present in eyes developing postoperative LASIK ectasia can be better understood using the Randleman Ectasia Risk Score System.Keywords: corneal topography, Ectasia Risk Score System, keratectasia, myopia, LASIK

  4. Effect of the multifunctional cosmetic ingredient sphinganine on hair loss in men and women with diffuse hair reduction

    Directory of Open Access Journals (Sweden)

    Gerlach N

    2016-09-01

    Full Text Available Nicole Gerlach,1,* Matthias Mentel,2,* Tim Köhler,2 Benjamin Tuchscherer,2 Birgit Garbe,1 Jasmina Ülker,1 Hagen Tronnier,1 Ulrike Heinrich,1 Mike Farwick2 1DermaTronnier GmbH & Co. KG, Institute for Experimental Dermatology, Witten/Herdecke University, Witten, 2Evonik Nutrition & Care GmbH, Essen, Germany *These authors contributed equally to this work Abstract: Sphingolipids are well known to promote keratinocyte differentiation and to induce ceramide production. In addition, they show anti-inflammatory and antimicrobial activities. Thus, the aim of this study is to investigate the potential effect of sphinganine on prolonging the hair anagen rate and improving the overall hair quality and scalp health. The inhibitory potential of sphinganine toward 5-α-reductase was studied using an in vitro assay. The stimulation of the antimicrobial peptide HBD2 by sphinganine was measured by real-time polymerase chain reaction and immunostaining. Sphinganine bioavailability was studied ex vivo using a pig skin model. A placebo-controlled, double-blind study was designed to evaluate the efficacy of sphinganine on hair loss and hair/scalp quality in vivo. In vitro results showed that sphinganine is a potent inhibitor of 5-α-reductase type I that prevents the conversion of testosterone to dihydrotestosterone, a key factor of androgenetic male baldness. In vivo results demonstrated efficacy in reducing non-illness-related hair loss among males. In terms of expert rating, all hair quality and scalp parameters improved after application of sphinganine. Improved scalp health might be linked to the observed increase of the antimicrobial peptide HBD2. Thus, sphinganine is well suited as a topical alternative for the improvement of scalp health and hair quality and anti-hair loss application. Keywords: sphinganine, 5-α-reductase inhibition, HBD2, hair loss, anagen rate, TrichoScan®

  5. Salustiano de Dios y Eugenia Torijano (coords., Cultura, política y práctica del Derecho. Juristas de Salamanca, Siglos XV-XX, Ediciones Universidad de Salamanca, Salamanca, 2012, 567 págs.

    Directory of Open Access Journals (Sweden)

    Guillermo Hierrezuelo Conde

    2013-03-01

    Full Text Available En esta obra se recogen hasta siete estudios relativos a juristas de Salamanca en el período que comprende desde el s. XV hasta el pasado siglo XX. El primero de ellos está dedicado a distintos juristas salmantinos que vivieron durante el s. XV, destacando la figura de Pedro de Luna, conocido como papa Benedicto XIII; el segundo de los artículos pone de relieve la importancia de los colegios mayores salmantinos, institución en la que se tramitaron numerosos expedientes a los colegiales para la averiguación de la limpieza de sangre, así como otros aspectos, como la honorabilidad de la línea familiar; la tercera de las colaboraciones gira en torno a la figura del oficial de la administración española en el s. XVIII, y a las referencias que sobre ella se recogen en la obra de Jean Pierre Dedieu titulada La muerte del letrado; el cuarto estudia la personalidad del catedrático Vicente Fernández de Ocampo, que vivió entre 1743 y 1815; el quinto al informe realizado al proyecto de Código Civil de 1851 por la Facultad de jurisprudencia de la Universidad de Salamanca, que aunque no llegó a entrar en vigor adquirió gran trascendencia en el ámbito civil; el sexto, a la importancia de las audiencias de lo criminal de Salamanca y Ciudad Rodrigo, hasta la supresión de esta última; y el último de ellos, a aquellos profesores de la Universidad de Salamanca que vivieron los primeros años de la Dictadura franquista, entre los que podemos citar a Teodoro Andrés Marcos y Nicolás Rodríguez Aniceto, entre otros.

  6. Networks of trainees: examining the effects of attending an interdisciplinary research training camp on the careers of new obesity scholars

    Directory of Open Access Journals (Sweden)

    Godley J

    2014-10-01

    Full Text Available Jenny Godley,1 Nicole M Glenn,2 Arya M Sharma,3 John C Spence4 1Department of Sociology, University of Calgary, Calgary, AB, Canada; 2School of Public Health, Université de Montréal, Montreal, QC, Canada; 3Department of Medicine, 4Sedentary Living Laboratory, Faculty of Physical Education and Recreation, University of Alberta, Edmonton, AB, Canada Abstract: Students training in obesity research, prevention, and management face the challenge of developing expertise in their chosen academic field while at the same time recognizing that obesity is a complex issue that requires a multidisciplinary and multisectoral approach. In appreciation of this challenge, the Canadian Obesity Network (CON has run an interdisciplinary summer training camp for graduate students, new career researchers, and clinicians for the past 8 years. This paper evaluates the effects of attending this training camp on trainees' early careers. We use social network analysis to examine the professional connections developed among trainee Canadian obesity researchers who attended this camp over its first 5 years of operation (2006–2010. We examine four relationships (knowing, contacting, and meeting each other, and working together among previous trainees. We assess the presence and diversity of these relationships among trainees across different years and disciplines and find that interdisciplinary contact and working relationships established at the training camp have been maintained over time. In addition, we evaluate the qualitative data on trainees' career trajectories and their assessments of the impact that the camp had on their careers. Many trainees report that camp attendance had a positive impact on their career development, particularly in terms of establishing contacts and professional relationships. Both the quantitative and the qualitative results demonstrate the importance of interdisciplinary training and relationships for career development in the health

  7. Attraction Effects in Honorific Agreement in Korean.

    Science.gov (United States)

    Kwon, Nayoung; Sturt, Patrick

    2016-01-01

    Previous studies have suggested that sentence processing is mediated by content-addressable direct retrieval processes (McElree, 2000; McElree et al., 2003). However, the memory retrieval processes may differ as a function of the type of dependency. For example, while many studies have reported facilitatory intrusion effects associated with a structurally illicit antecedent during the processing of subject-verb number or person agreement and negative polarity items (Pearlmutter et al., 1999; Xiang et al., 2009; Dillon et al., 2013), studies investigating reflexives have not found consistent evidence of intrusion effects (Parker et al., 2015; Sturt and Kwon, 2015; cf. Nicol and Swinney, 1989; Sturt, 2003). Similarly, the memory retrieval processes could be also sensitive to cross-linguistic differences (cf. Lago et al., 2015). We report one self-paced reading experiment and one eye-tracking experiment that examine the processing of subject-verb honorific agreement, a dependency that is different from those that have been studied to date, in Korean, a typologically different language from those previously studied. The overall results suggest that the retrieval processes underlying the processing of subject-verb honorific agreement in Korean are susceptible to facilitatory intrusion effects from a structurally illicit but feature-matching subject, with a pattern that is similar to subject-verb agreement in English. In addition, the attraction effect was not limited to the ungrammatical sentences but was also found in grammatical sentences. The clear attraction effect in the grammatical sentences suggest that the attraction effect does not solely arise as the result of an error-driven process (cf. Wagers et al., 2009), but is likely also to result from general mechanisms of retrieval processes of activating of potential items in memory (Vasishth et al., 2008).

  8. Occurrence and succession of mycorrhizas in Alnus incana

    Energy Technology Data Exchange (ETDEWEB)

    Arveby, A.S. [Swedish Univ. of Agricultural Sciences, Uppsala (Sweden). Section of Forest Ecophysiology; Granhall, U. [Swedish Univ. of Agricultural Sciences, Uppsala (Sweden). Dept. of Microbiology

    1998-12-31

    The occurrence of different mycorrhizas of the grey alder, Alnus incana (L.) Moench., in Sweden was investigated. Root sampling was carried out in planted and natural grey alder stands, representing different soil types, geographical sites, and plant ages. Mycorrhizal infection of roots was found to be frequent at all investigated sites, except for some planted peat bogs, where alders do not occur naturally. At the latter sites, mycorrhizal infection was less frequent and consisted only of ectomycorrhizas. Young trees here were non-mycorrhizal. At all other sites vesicular-arbuscular mycorrhiza (VAM) was found to be the almost exclusive type of mycorrhiza in first-year seedlings. In trees older than one year ectomycorrhiza was the dominating type. In the planted stands up to five years of age no fruitbodies of ectomycorrhizal fungi were found. In such stands the ectomycorrhizas generally had thin, translucent mantles and could be observed only by microscopic examination. In one old plantation (27 years) and in the natural stands sporocarps of several specific `alder fungi` were found. Here, the mycorrhizal root tips had thick, mostly whitish mantles. The Hartig net was in all cases confined to penetration between epidermal cells. Soil collected from one alder site and two non-alder biotopes readily infected grey alder seedlings with Frankia and VAM fungi whereas a peat soil failed to infect seedlings with any symbiont. In vitro inoculation of nodulated seedlings with Glomus mossae (Nicol. and Gerd.) Gerdemann and Trappe resulted in VAM-infection. Simultaneous syntheses with isolates of alder-specific, and other, ectomycorrhizal fungi, using three different methods, failed. On the basis of these results an endomycorrhizal-ectomycorrhizal succession after the first growth season in Alnus incana is concluded. A subsequent succession of ectomycorrhizal species from early-stage to late-stage ones is discussed 58 refs, 3 figs, 2 tabs

  9. Inoculum density of Glomus mosseae and growth of onion plants in unsterilized bituminous coal spoil

    Energy Technology Data Exchange (ETDEWEB)

    Khan, A.G.

    1988-01-01

    The effect of inoculum, density (number of vesicular-arbuscular mycorrhizal (VAM) propagules g/sup -1/ of inoculum) on the growth of onions (Allium cepa L.) infected by Glomus mosseae (Nicol and Gerd). Gerdemann and Trappe, Comb nov in unsterilized coal spoil containing indigenous VAM fungi, including G. mosseae, was investigated. The amount of onion roots converted to mycorrhizas by inoculant fungus, estimated by a gridline intersect method, increased with inoculum density (..gamma..0.62, P0.05) until a plateau was reached. Onion growth responses also increased significantly (P<0.05) with the amount of VAM inoculum present in the coal spoil. The initial linear relationship between inoculum propagules (MPN estimates), percent colonization of onion roots and onion shoot dry weight became quadratic as the number of infection propagules increased. VAM infection had no significant effect on root:shoot ratios. Similarly there was no significant interaction (P>0.05) between the inoculum density, VAM-colonized root mass and the onion root:shoot fresh weight ratios. The amount of the windswept bituminous coal spoil bound to VAM (presumably because of VAM external hyphae) also increased as inoculum density increased (..gamma..0.63, P<0.05). There was a stronger correlation (ga0.85, P<0.05) between the amount of spoil adhered per plant and the root fresh wt plant/sup -1/ indicating that root effects were primarily responsible for increasing spoil adherence. There were negative correlations (P<0.05) between root fresh wt plant/sup -1/ (..gamma..-0.68), inoculum density (..gamma..-0.589), percent root elngth infected (..gamma..-0.73) and the amount of spoil adhered g/sup -1/ root fresh wt. The possible exploitation of VAM in revegetation of bituminous coal spoil is discussed. 25 refs., 2 tabs.

  10. Is envy harmful to a society's psychological health and wellbeing? A longitudinal study of 18,000 adults.

    Science.gov (United States)

    Mujcic, Redzo; Oswald, Andrew J

    2018-02-01

    Nearly 100 years ago, the philosopher and mathematician Bertrand Russell warned of the social dangers of widespread envy. One view of modern society is that it is systematically developing a set of institutions -- such as social media and new forms of advertising -- that make people feel inadequate and envious of others. If so, how might that be influencing the psychological health of our citizens? This paper reports the first large-scale longitudinal research into envy and its possible repercussions. The paper studies 18,000 randomly selected individuals over the years 2005, 2009, and 2013. Using measures of SF-36 mental health and psychological well-being, four main conclusions emerge. First, the young are especially susceptible. Levels of envy fall as people grow older. This longitudinal finding is consistent with a cross-sectional pattern noted recently by Nicole E. Henniger and Christine R. Harris, and with the theory of socioemotional regulation suggested by scholars such as Laura L. Carstensen. Second, using fixed-effects equations and prospective analysis, the analysis reveals that envy today is a powerful predictor of worse SF-36 mental health and well-being in the future. A change from the lowest to the highest level of envy, for example, is associated with a worsening of SF-36 mental health by approximately half a standard deviation (p < .001). Third, no evidence is found for the idea that envy acts as a useful motivator. Greater envy is associated with slower -- not higher -- growth of psychological well-being in the future. Nor is envy a predictor of later economic success. Fourth, the longitudinal decline of envy leaves unaltered a U-shaped age pattern of well-being from age 20 to age 70. These results are consistent with the idea that society should be concerned about institutions that stimulate large-scale envy. Copyright © 2018 Elsevier Ltd. All rights reserved.

  11. US veterans and their unique issues: enhancing health care professional awareness

    Directory of Open Access Journals (Sweden)

    Olenick M

    2015-12-01

    Full Text Available Maria Olenick,1 Monica Flowers,1 Valerie J Diaz1,21Nicole Wertheim College of Nursing and Health Science, Florida International University, Miami, FL, USA; 2Operational Health Support Unit Jacksonville, United States Navy Nurse Corps, Jacksonville, FL, USAAbstract: United States veterans are a multifaceted population with a distinct culture that includes, but is not limited to, values, customs, ethos, selfless duty, codes of conduct, implicit patterns of communication, and obedience to command. Veterans experience mental health disorders, substance use disorders, post-traumatic stress, and traumatic brain injury at disproportionate rates compared to their civilian counterparts. Eighteen to 22 American veterans commit suicide daily and young veterans aged 18–44 are most at risk. Health care professionals must be aware of patients' military history and be able to recognize suicide-risk factors, regardless of age. Advancement in medical technology has allowed servicemen to survive their injuries but, for many, at the cost of a traumatic limb amputation and associated mental scarring. Health care professionals must be able to address physical safety concerns, as well as, emotional health of veterans. Approximately 49,933 American veterans are homeless and face the same difficulties as non-veterans in addition to service-related matters. Separation from military service and issues related to complex multiple deployments are among specifically identified veteran issues. Successful veteran reintegration into civilian life rests upon providing veterans with training that builds on their military knowledge and skill, employment post-separation from service, homelessness prevention, and mental health programs that promote civilian transition. Preparing health care providers to meet the complex needs of a vast veteran population can be facilitated by implementing veteran content into curricula that includes veteran patient simulations and case studies

  12. Histological features of layers and sublayers in cortical visual areas V1 and V2 of chimpanzees, macaque monkeys, and humans

    Directory of Open Access Journals (Sweden)

    Balaram P

    2014-09-01

    Full Text Available Pooja Balaram, Nicole A Young, Jon H Kaas Department of Psychology, Vanderbilt University, Nashville, TN, USA Abstract: The layers and sublayers of primary visual cortex, or V1, in primates are easily distinguishable compared to those in other cortical areas, and are especially distinct in anthropoid primates – monkeys, apes, and humans – where they also vary in histological appearance. This variation in primate-specific specialization has led to a longstanding confusion over the identity of layer 4 and its proposed sublayers in V1. As the application of different histological markers relate to the issue of defining and identifying layers and sublayers, we applied four traditional and four more recent histological markers to brain sections of V1 and adjoining secondary visual cortex (V2 in macaque monkeys, chimpanzees, and humans in order to compare identifiable layers and sublayers in both cortical areas across these species. The use of Nissl, neuronal nuclear antigen (NeuN, Gallyas myelin, cytochrome oxidase (CO, acetylcholinesterase (AChE, nonphosphorylated neurofilament H (SMI-32, parvalbumin (PV, and vesicular glutamate transporter 2 (VGLUT2 preparations support the conclusion that the most popular scheme of V1 lamination, that of Brodmann, misidentifies sublayers of layer 3 (3Bβ and 3C as sublayers of layer 4 (4A and 4B, and that the specialized sublayer of layer 3 in monkeys, 3Bβ, is not present in humans. These differences in interpretation are important as they relate to the proposed functions of layer 4 in primate species, where layer 4 of V1 is a layer that receives and processes information from the visual thalamus, and layer 3 is a layer that transforms and distributes information to other cortical areas. Keywords: area 17, area 18, cortical layers, histology, immunohistochemistry

  13. The effects of hydroxy fatty acids on the hyphal branching of germinated spores of AM fungi.

    Science.gov (United States)

    Nagahashi, Gerald; Douds, David D

    2011-01-01

    Two hydroxy fatty acids, tentatively identified previously in carrot root exudates, were tested for their effects on hyphal growth of the arbuscular mycorrhizal (AM) fungus, Gigaspora gigantea (Nicol. and Gerd.) Gerdemann and Trappe. Best results were achieved with a long-term bioassay (7-8d) with nanomolar concentrations throughout the Petri dish in contrast to the rapid microinjection bioassay (16-24h) in which nanogram quantities were injected near growing hyphal tips. When 5nM 2-hydroxy fatty acids of various chain length were tested, the length of the hydroxyl fatty acid was significant since only 2-hydroxytetradecanoic acid (2OH-TDA) and to a slightly lesser degree, 2-hydroxydodecanoic acid (2OH-DDA) induced a hyphal growth response while 2-hydroxydecanoic acid (2OH-DA) and 2-hydroxyhexadecanoic (2OH-HDA) acid did not. The position of the hydroxyl group was critical since 5nM 3-hydroxytetradecanoic acid (3OH-TDA) had no effect on hyphal growth. The length of the non-hydroxy containing straight chain fatty acid, per se, did not appear significant since none of these fatty acids had an effect on hyphal growth. The morphological growth response promoted by 2OH-TDA consisted of multiple lateral branches, spaced fairly regularly apart, along the primary germ tubes as well as some lateral branch formation off the major secondary hyphae. This growth response was identical to that observed when germinated spores were allowed to grow towards cultured carrot roots in vitro. This response to 2OH-TDA also was observed with an unidentified Gigaspora species but no morphological response was observed with Glomus intraradices Schenck and Smith. The results indicate that 2-hydroxy fatty acids are another putative category of root exudate signals perceived by Gigaspora species, stimulating an increase in elongated lateral branches. Published by Elsevier Ltd.

  14. Topical retapamulin in the management of infected traumatic skin lesions

    Directory of Open Access Journals (Sweden)

    Ribhi Shawar

    2008-12-01

    Full Text Available Ribhi Shawar1, Nicole Scangarella-Oman1, MaryBeth Dalessandro2, John Breton2, Monique Twynholm3, Gang Li4, Harmony Garges51Infectious Disease Center for Excellence in Drug Discovery, GlaxoSmithKline, Collegeville, PA, USA; 2Anti-infectives Medicine Development Center, GlaxoSmithKline, Collegeville, PA, USA; 3Infectious Diseases Medicine Development Centre Europe, GlaxoSmithKline, Greenford, Middlesex, UK; 4MDC BDS – Infectious Disease, GlaxoSmithKline, Collegeville, PA, USA; 5Anti-infectives Medicine Development Center, GlaxoSmithKline, Research Triangle Park, NC, USAAbstract: Retapamulin is a novel semisynthetic pleuromutilin antibiotic specifically designed for use as a topical agent. The unique mode of action by which retapamulin selectively inhibits bacterial protein synthesis differentiates it from other nonpleuromutilin antibacterial agents that target the ribosome or ribosomal factors, minimizing the potential for target-specific cross-resistance with other antibacterial classes in current use. In vitro studies show that retapamulin has high potency against the Gram-positive bacteria (Staphylococcus aureus, Streptococcus pyogenes, and coagulase-negative staphylococci commonly found in skin and skin-structure infections (SSSIs, including S. aureus strains with resistance to agents such as macrolides, fusidic acid, or mupirocin, and other less common organisms associated with SSSIs, anaerobes, and common respiratory tract pathogens. Clinical studies have shown that twice-daily topical retapamulin for 5 days is comparable to 10 days of oral cephalexin in the treatment of secondarily infected traumatic lesions. A 1% concentration of retapamulin ointment has been approved for clinical use as an easily applied treatment with a short, convenient dosing regimen for impetigo. Given the novel mode of action, low potential for cross-resistance with established antibacterial agents, and high in vitro potency against many bacterial pathogens

  15. Champagne Pool (New Zealand) Thermophiles Yield Insights into the Evolution of Microbial Arsenic Resistance

    Science.gov (United States)

    Hug, K.; Krikowa, F.; Morgan, X.; Maher, W. A.; Stott, M. B.; Moreau, J. W.

    2011-12-01

    detoxification mechanism. These results yield insights into potential arsenic detoxification strategies that may have fostered the evolution of thermophiles in ancient geothermal systems. Ref. : Childs A.M., Mountain B.W., O'Toole R., Stott M.B. (2008). "Relating Microbial Community and Physiochemical parameters of a Hot Spring: Champagne Pool, Wai-o-tapu, New Zealand." Geomicrobiology Journal 25 (7-8):441-453.

  16. Uncommon disorders and decay in near-isogenic lines of melon and reference cultivars Acidentes fisiológicos e podridões atípicas em linhas quase-isogénicas de melão e em cultivares de referência

    Directory of Open Access Journals (Sweden)

    Juan Antonio Martínez

    2009-12-01

    Full Text Available Postharvest disorders and rots can produce important economic losses in fruits stored for long time for exportation. The genetic and physiological basis of some disorders in melon (Cucumis melo L. are unknown and particularly the possible relation with climacteric behavior. A collection of melon near-isogenic lines (NILs (SC3-5 and seven more showing climacteric and two non-climacteric ripening pattern were analyzed to study genetic and physiological aspects of fruit disorders and rots. Two non-climacteric (Nicolás; Inodorus Group; and Shongwan Charmi PI161375, Conomon Group and two climacteric cultivars (Fado, Reticulatus Group; Védrantais, Cantaloupensis Group were used as reference. The field was divided in eight blocks containing one three-plant replication for each NIL, two for the parental cultivar Piel de Sapo and one or two for the reference cultivars. Replications evaluated were more than six in the cultivars studied. Plant problems included aphids, powdery mildew, and leaf wind injury. Preharvest fruit disorders included whole fruit cracking in cultivar Védrantais and NIL 5M2, and stylar-end cracking in cultivar Fado. Climacteric NILs with yellow skin were particularly affected by over-ripening, stylar-end cracking, and sunburn during cultivation. At harvest, two NILs showed slight placental tissue necrosis which was inherited from SC and were also detected after storage. Other uncommon disorders seen at harvest or 30 days after storage at 8ºC included warted skin (scarring, flesh discoloration (light brown or translucent areas, hollow flesh disorder, and deep furrow netting inherited from SC. Less common rots included grey mould, bacterial soft rot, Penicillium rot, cottony leak and internal Cladosporium rot. Stylar-end hardness below 20 N·mm-1 was associated with cracking and softening. The incidence of the disorders and rots was too low to confirm that the genetic component played a role in their development

  17. Parole et identité humaine à l’âge classique

    Directory of Open Access Journals (Sweden)

    Pascale Gillot

    2010-03-01

    Full Text Available En prenant appui sur des textes de Descartes et de philosophes post-cartésiens comme Géraud de Cordemoy, ou encore des théoriciens de Port-Royal, tels Lancelot, Arnauld et Nicole, nous nous intéressons au statut double et paradoxal que revêt la parole dans la philosophie classique, au moment où se construit la question de l’union psychophysique et où sont proposées diverses « réponses » à cette question, dans la perspective d’une conceptualisation nouvelle d’une identité humaine rendue problématique. Le paradoxe tient au fait que l’activité de langage est d’abord manifestation de la pensée, indice publiquement observable ou témoignage extérieur de l’existence d’un esprit à l’origine des actes linguistiques, conformément à la théorie cartésienne à ce sujet ; mais la parole dénote aussi, dans la philosophie même de Descartes, une faculté spécifiquement humaine, propre au « vrai homme », en tant qu’il est indissolublement esprit et corps. Nous tentons de montrer que ce qui est en jeu dans les études brèves et éparses que Descartes consacre au langage, puis dans les développements ultérieurs de la Grammaire générale et raisonnée et de la Logique de Port-Royal, à travers la théorie du signe linguistique et de la signification, c’est la compréhension de la relation, nécessairement postulée et pourtant constamment renvoyée à l’ordre d’un lien contre-nature, et par là arbitraire, fruit d’une institution, entre la parole comme phénomène physique et la parole comme activité symbolique par excellence ; si bien que le prodige du phénomène humain du langage, comme expression publique des pensées, donne la mesure de l’énigme que constitue l’unité en l’homme du corps et de l’esprit.The aim of this paper is to lay emphasis on the connection between the mind-body problem and the theory of language which is developed in early-modern philosophy by Descartes and post

  18. Derecho y Literatura: Anatoliĭ Fedorovich Koni (1844-1927 (Sobre Cultura jurídica de la literatura y Cultura literaria del Derecho en la Rusia imperial de Alejandro II a Nicolás II

    Directory of Open Access Journals (Sweden)

    José Calvo González

    2011-01-01

    Full Text Available El trabajo aborda la figura del eminente jurista ruso Anatoliĭ Fedorovich Koni, representativa de la corriente jurídica liberal-moderada en la etapa prerevolucionaria de Rusia. Recupera en su obra su interés por el gran mentor de la literatura rusa moderna, Pushkin, que vincula al programa de modernización inaugurado con las reformas judiciales de 1864. Detalla igualmente las relaciones personales con escritores contemporáneos, entre los que aparecen Chéjov, Dostoiesvki y Tolstói. Sobre esta base proyecta las imbricaciones Derecho y Literatura en una doble dirección, incluyendo las reflexiones jurídicas a partir de textos literarios así como las potencialidades de las categorías jurídicas en la creación literaria. Finalmente, inserta ambas construcciones en el ambiente de una cultura literaria y jurídica que estaba prefigurando el modernismo literario y (efímero y fallido modernismo jurídico.

  19. Cost of tumor necrosis factor blockers per patient with rheumatoid arthritis in a multistate Medicaid population

    Directory of Open Access Journals (Sweden)

    Bonafede M

    2014-09-01

    Full Text Available Machaon Bonafede,1 George J Joseph,2 Neel Shah,2 Nicole Princic,1 David J Harrison2 1Truven Health Analytics, Cambridge, MA, 2Amgen Inc., Thousand Oaks, CA, USA Background: The purpose of this study was to estimate the annual cost per treated patient for the tumor necrosis factor (TNF blockers, etanercept, adalimumab, and infliximab in rheumatoid arthritis (RA patients covered by Medicaid. Methods: The MarketScan Medicaid Multistate Database was used to identify adult RA patients who used etanercept, adalimumab, or infliximab (index agents from 2007 to 2011. The index date was the first claim preceded by 180 days and followed by 360 days of continuous enrollment. Patients with other conditions for which these agents are approved by the US Food and Drug Administration were excluded. “Continuing” patients had one or more pre-index claim for their index biologic, and "new" patients did not. Cost per treated patient was calculated in the 360 day post-index period for each index agent as the total index drug and administration cost to the payer and the costs of switched-to agents divided by the number of patients who received the index agent. Results: A total of 1,085 patients met the study criteria. Forty-eight percent received etanercept (n=521; 37% received adalimumab (n=405; and 15% received infliximab (n=159. Patient characteristics were similar across groups (mean age 47.4 years, 83% female. The annual cost per treated patient was lowest for etanercept ($18,466, followed by adalimumab ($20,983 and infliximab ($26,516. For all agents, annual costs were lower for new patients ($17,996 for etanercept, $18,992 for adalimumab, and $24,756 for infliximab than for continuing patients ($19,004 for etanercept, $24,438 for adalimumab, and $28,127 for infliximab. Conclusion: Etanercept had lower costs per treated patient than adalimumab or infliximab in both new and continuing Medicaid enrollees with RA. Keywords: cost, tumor necrosis factor

  20. Identifying and assessing the risk of opioid abuse in patients with cancer: an integrative review

    Directory of Open Access Journals (Sweden)

    Carmichael AN

    2016-06-01

    Full Text Available Ashley-Nicole Carmichael,1 Laura Morgan,1 Egidio Del Fabbro2 1School of Pharmacy, 2Division of Hematology, Oncology, and Palliative Care, Virginia Commonwealth University, Richmond, VA, USA Background: The misuse and abuse of opioid medications in many developed nations is a health crisis, leading to increased health-system utilization, emergency department visits, and overdose deaths. There are also increasing concerns about opioid abuse and diversion in patients with cancer, even at the end of life. Aims: To evaluate the current literature on opioid misuse and abuse, and more specifically the identification and assessment of opioid-abuse risk in patients with cancer. Our secondary aim is to offer the most current evidence of best clinical practice and suggest future directions for research. Materials and methods: Our integrative review included a literature search using the key terms “identification and assessment of opioid abuse in cancer”, “advanced cancer and opioid abuse”, “hospice and opioid abuse”, and “palliative care and opioid abuse”. PubMed, PsycInfo, and Embase were supplemented by a manual search. Results: We found 691 articles and eliminated 657, because they were predominantly noncancer populations or specifically excluded cancer patients. A total of 34 articles met our criteria, including case studies, case series, retrospective observational studies, and narrative reviews. The studies were categorized into screening questionnaires for opioid abuse or alcohol, urine drug screens to identify opioid misuse or abuse, prescription drug-monitoring programs, and the use of universal precautions. Conclusion: Screening questionnaires and urine drug screens indicated at least one in five patients with cancer may be at risk of opioid-use disorder. Several studies demonstrated associations between high-risk patients and clinical outcomes, such as aberrant behavior, prolonged opioid use, higher morphine-equivalent daily dose

  1. Sociólogos o “sociólogos”: la polémica de 1959.

    Directory of Open Access Journals (Sweden)

    ORLANDO FALS BORDA, ÓSCAR DELGADO, RODR Varón

    2009-07-01

    Full Text Available Cuando el 10 de Diciembre de 1982, Salvador Camacho Roldán, al pronunciar el discurso de clausura de las actividades académicas de la Universidad Nacional, tomó como asunto la propuesta de una nueva cátedra, una sobre una novísima disciplina (tal como se le veía en ese momento: la Sociología, a la vez, inauguró un debate de largo alcance que llega a nuestros días. En aquel momento, dos de los participantes, Nicolás Tanco Armero y Rafael Núñez, presidente de la República, sustentaron con minuciosidad sus argumentos y, al hacerlo, ofrecieron sendas muestras del nivel cultural del momento, de la sintonía en la que se hallaban, en contraste con lo que en otras latitudes se discutía, así como con corrientes percibidas como universales. El valor documental de las piezas de ese debate inaugural ha hecho que se las reedite de cuando en cuando; incluso, el propio Departamento de Sociología lo ha realizado en dos ocasiones. Menos conocido es el debate que se produjera en un suplemento literario de circulación nacional, con motivo de la inauguración de la enseñanza de la sociología en 1959, que, visto de manera retrospectiva, guarda más de una analogía con el debate inicial. En respuesta al discurso inaugural de Orlando Fals Borda, un articulista (Óscar Delgado discute la naturaleza de la disciplina, y la tradición de pensamiento en la que se ubica; y, a su vez, replican y controvierten, algunos de quienes se hallaban entonces como sociólogos en formación y hoy son ya figuras de trayectoria (como son Guillermo Varela, Rodrigo Parra y Francisco A. Correa. Como una contribución a que la conmemoración no sea un rito vano, creemos conveniente reeditar tales documentos.

  2. AULUS AURELIUS CORNELIUS CELSUS. Su aporte a las Ciencias Neurológicas

    Directory of Open Access Journals (Sweden)

    Germán Peña Quiñones

    2010-06-01

    Full Text Available

    Una figura muy importante de la medicina romana fue Aulus Aurelius Cornelius Celsus (25AC-50AD (Celsus, quién probablemente fue consejero de los emperadores Tiberio y Calígula. Poco se sabe sobre su vida y origen, algunos historiadores lo catalogan como un recopilador de los conocimientos médicos de la época; otros cuestionan si fue médico o cirujano pero por sus escritos se deduce que debió practicar tanto la medicina como la cirugía. Se cree que pudo nacer en Galia o Hispania o aún en Roma. Su mérito mayor es que recopiló y consignó los conocimientos médicos de la época en su tratado “De Re Medicina” libro que duró perdido hasta el año 1443 cuando fue descubierto por Tomás Perentocelli de Sarazanne, quién posteriormente se convirtió en el Papa Nicolás V y su libro fue el primer manuscrito médico que fue impreso, lo que ocurrió en 1478.

    Según Celso y el conocimiento de su época, las lesiones que puede sufrir el cuerpo, eran de cinco clases: “las que resultan de un agente externo, como ocurre con las heridas; las que dependen de una enfermedad interna , como el cáncer; las originadas por la formación de cuerpos extraños, como los cálculos de la vejiga; las debidas a un desarrollo anómalo, como ocurre con las venas varicosas; y por último las lesiones por defecto, es decir, aquellas en que una parte es demasiado corta. De estas afecciones, unas reclaman el auxilio de los medicamentos y otras, exigen más especialmente la ayuda de la cirugía”.

  3. Metabolic profiling of plasma amino acids shows that histidine increases following the consumption of pork

    Directory of Open Access Journals (Sweden)

    Samman S

    2014-06-01

    Full Text Available Samir Samman,1 Ben Crossett,2 Miles Somers,1 Kirstine J Bell,1 Nicole T Lai,1,3 David R Sullivan,3 Peter Petocz4 1Discipline of Nutrition and Metabolism, 2Discipline of Proteomics and Biotechnology, School of Molecular Bioscience, University of Sydney, Sydney, NSW, Australia; 3Department of Clinical Biochemistry, Royal Prince Alfred Hospital, Sydney, NSW, Australia; 4Department of Statistics, Macquarie University, Sydney, NSW, Australia Abstract: Amino acid (AA status is determined by factors including nutrition, metabolic rate, and interactions between the metabolism of AA, carbohydrates, and lipids. Analysis of the plasma AA profile, together with markers of glucose and lipid metabolism, will shed light on metabolic regulation. The objectives of this study were to investigate the acute responses to the consumption of meals containing either pork (PM or chicken (CM, and to identify relationships between plasma AA and markers of glycemic and lipemic control. A secondary aim was to explore AA predictors of plasma zinc concentrations. Ten healthy adults participated in a postprandial study on two separate occasions. In a randomized cross-over design, participants consumed PM or CM. The concentrations of 21 AA, glucose, insulin, triglycerides, nonesterified fatty acids, and zinc were determined over 5 hours postprandially. The meal composition did not influence glucose, insulin, triglyceride, nonesterified fatty acid, or zinc concentrations. Plasma histidine was higher following the consumption of PM (P=0.014, with consistently higher changes observed after 60 minutes (P<0.001. Greater percentage increases were noted at limited time points for valine and leucine + isoleucine in those who consumed CM compared to PM. In linear regression, some AAs emerged as predictors of the metabolic responses, irrespective of the meal that was consumed. The present study demonstrates that a single meal of PM or CM produces a differential profile of AA in the

  4. Arbuscular mycorrhizal fungi and Zn accumulation in the metallophytic plant Viola calaminaria (Gingins. Lej.

    Directory of Open Access Journals (Sweden)

    O. Fernández-Fernández

    2008-01-01

    Full Text Available Los hongos micorrízico arbusculares (HMA incrementan la tolerancia a metales en la mayoría de sus plantas hospederas, sin embargo, se conoce poco de su efecto en plantas metalófitas. Los objetivos de esta investigación fueron: 1 determinar la respuesta a la inoculación con dos HMA de Viola calaminaria (Gingins. Lej., una planta endémica de suelos contaminados con metales pesados, y 2 investigar el efecto de la inoculación con HMA en la acumulación de zinc. Se establecieron dos experimentos: El primero duró tres meses y consistió en la inoculación de plantas de V. calaminaria con dos HMA utilizando arena de río como sustrato de crecimiento. El segundo experimento duró dos semanas y consideró el efecto de la inoculación de las plantas procedentes del primer experimento y que se transfirieron a condiciones de hidroponia con diferentes niveles de Zn+2 (50, 200, 300 y 400 mg.litro-1. Los HMA que se estudiaron fueron dos aislados de Glomus mosseae (Nicol. & Gerd. Gerd. & Trappe: BEG-132- y BEG-25, los cuales se aislaron, respectivamente, de suelos contaminados o no con metales pesados. El experimento 1 mostró que las raíces de V. calaminaria se colonizaron por ambos aislados micorrízicos; sin embargo las plantas no presentaron beneficios en relación a crecimiento, desarrollo y nutrición. El segundo experimento mostró que la inoculación incrementó el contenido total de Zn por planta y que el aislado BEG 25 fue el que mayor influencia tuvo. La colonización micorrízica en las raíces de V. calaminaria no se afectó por las concentraciones de Zn. Resulta relevante continuar experimentos de este tipo para conocer si los HMA adaptados a altos contenidos de metales pesados confieren ventajas sobre crecimiento y supervivencia en campo en estas y otras plantas metalíferas.

  5. Biomass valorisation, a new dynamics for French agriculture. Colloquium proceedings

    International Nuclear Information System (INIS)

    2006-04-01

    This document brings together the summary of the presentations given at this colloquium on French agriculture and biomass valorisation and the slides of the available presentations as well. The colloquium started with the opening talk by D. Bussereau (Ministry of agriculture and fisheries) who presented an international overview of biomass activities. The colloquium was divided in two parts with presentations and round-tables: 1 - the post-petroleum era: energy context and raw materials market (P. Chalmin, Cyclope); first round-table on biofuels today and tomorrow; back to the basics (C. Roy); 2 - Biomass and industry: second round-table on cellulose - an oldie promised to a bright future; status of biomass valorisation (M. Pappalardo, ADEME); third round-table: the boom of green chemistry; closing talk by C. Roy. Sixteen presentations (slides) are attached to the document: 1 - Opening talk (D. Bussereau, Ministry of agriculture and fisheries); 2 - Biomass, agriculture, forestry and climate, some basics (C. Roy); 3 - Role of biomass in the fight against climate change and in supplies diversification (M. Pappalardo, Ademe); 4 - The 2005/2006 shock on world markets: energy and raw materials (P. Chalmin, Cyclope); 5 - Actions in the energy domain (A. Chosson, CLCV); 6 - Ethanol production (A. Jeanroy); 7 - The 'biofuels' commitment of PSA Peugeot Citroen car maker (Beatrice Perrier-Maurer, PSA); 8 - Bio-diesel development (Bernard Nicol, Diester Industrie); 9 - First round-table on biofuels today and tomorrow: biofuels and conventional fuels - for an harmonious development of resources and outlets (J.B. Sigaud, Petroleum and Engines School); 10 - Agriculture biomass: source of cellulose (C. Burren, Ungrains, Arvalis); 11 - Electrical and thermal valorisations of biomass (C. Jurczak, MINEFI/DGEMP); 12 - Some elements of thought on new uses of biomass as 'material' (Jacques Sturm, Afocel) 13 - Presentation of Agrice (Agriculture for chemistry and energy) research

  6. Long-Term Intermittent Exposure to High Altitude Elevates Asymmetric Dimethylarginine in First Exposed Young Adults.

    Science.gov (United States)

    Lüneburg, Nicole; Siques, Patricia; Brito, Julio; De La Cruz, Juan José; León-Velarde, Fabiola; Hannemann, Juliane; Ibanez, Cristian; Böger, Rainer H

    2017-09-01

    Lüneburg, Nicole, Patricia Siques, Julio Brito, Juan José De La Cruz, Fabiola León-Velarde, Juliane Hannemann, Cristian Ibanez, and Rainer Böger. Long-term intermittent exposure to high altitude elevates asymmetric dimethylarginine in first exposed young adults. High Alt Med Biol. 18:226-233, 2017.-Hypoxia-induced dysregulation of pulmonary and cerebral circulation may be related to an impaired nitric oxide (NO) pathway. We investigated the effect of chronic intermittent hypobaric hypoxia (CIH) on metabolites of the NO pathway. We measured asymmetric and symmetric dimethylarginine (ADMA and SDMA) and monomethyl-L-arginine (L-NMMA) and assessed their associations with acclimatization in male draftees (n = 72) undergoing CIH shifts at altitude (3550 m) during 3 months. Sixteen Andean natives living at altitude (3675 m) (chronic hypobaric hypoxia [CH]) were included for comparison. In CIH, ADMA and L-NMMA plasma concentrations increased from 1.14 ± 0.04 to 1.95 ± 0.09 μmol/L (mean ± SE) and from 0.22 ± 0.07 to 0.39 ± 0.03 μmol/L, respectively, (p < 0.001 for both) after 3 months, whereas SDMA did not change. The concentrations of ADMA and L-NMMA were higher in CH (3.48 ± 0.07, 0.53 ± 0.08 μmol/L; p < 0.001) as compared with CIH. In both CIH and CH, ADMA correlated with hematocrit (r 2  = 0.07, p < 0.05; r 2  = 0.26; p < 0.01). In CIH, an association of ADMA levels with poor acclimatization status was observed. We conclude that the endogenous NO synthase inhibitors, ADMA and L-NMMA, are elevated in hypoxia. This may contribute to impaired NO production at altitude and may also be predictive of altitude-associated health impairment.

  7. The application of isotopic ({sup 32}P and {sup 15}N) dilution techniques to evaluate the interactive effect of phosphate-solubilizing rhizobacteria, mycorrhizal fungi and Rhizobium to improve the agronomic efficiency of rock phosphate for legume crops

    Energy Technology Data Exchange (ETDEWEB)

    Barea, J.M. [Departamento de Microbiologia del Suelo y Sistemas Simbioticos (Spain)]. E-mail: jmbarea@eez.csic.es; Toro, M.; Azcon, R. [Departamento de Microbiologia del Suelo y Sistemas Simbioticos (Spain); Orozco, M.O. [Instituto de Sistematica y Ecologia, Academia Cubana de Ciencias, Habana (Cuba); Campos, E. [Departamento de Ciencias de la Tierra y Quimica Ambiental Estacion Experimental del Zaidin (CSIC), Granada (Spain); Azcon, R. [Departamento de Microbiologia del Suelo y Sistemas Simbioticos (Spain)

    2002-05-15

    A pot experiment was designed to evaluate the interactive effects of multifunctional microbial inoculation treatments and rock phosphate (RP) application on N and P uptake by alfalfa through the use of {sup 15}N and {sup 32}P isotopic dilution approaches. The microbial inocula consisted of a wild type (WT) Rhizobium meliloti strain, the arbuscular mycorrhizal (AM) fungus Glomus mosseae (Nicol. and Gerd.) Gerd. and Trappe, and a phosphate solubilizing rhizobacterium (Enterobacter sp.). Inoculated microorganisms were established in the root tissues and/or in the rhizosphere soil of alfalfa plants (Medicago sativa L.). Improvements in N and P accumulation in alfalfa corroborate beneficial effects of Rhizobium and AM interactions. Inoculation with selected rhizobacteria improved the AM effect on N or P accumulation in both the RP-added soil and in the non RP-amended controls. Measurements of the {sup 15}N/{sup 14}N ratio in plant shoots indicate an enhancement of the N{sub 2} fixation rates in Rhizobium-inoculated AM-plants, over that achieved by Rhizobium in non-mycorrhizal plants. Whether or not RP was added, AM-inoculated plants showed a lower specific activity ({sup 32}P/{sup 31}P) than did their comparable non-mycorrhizal controls, suggesting that the plant was using otherwise unavailable P sources. The phosphate-solubilizing, AM-associated, microbiota could in fact release phosphate ions, either from the added RP or from the indigenous 'less-available' soil phosphate. A low Ca concentrations in the test soil may have benefited P solubilization. Under field conditions, the inoculation with AM fungi significantly increased plant biomass and N and P accumulation in plant tissues. Phosphate-solubilizing rhizobacteria improved mycorrhizal responses in soil dually receiving RP and organic matter amendments. Organic matter addition favoured RP solubilization. This, together with a tailored microbial inoculation, increased the agronomic efficiency of RP in the

  8. Gene polymorphisms in association with self-reported stroke in US adults

    Directory of Open Access Journals (Sweden)

    Amy Z Fan

    2010-03-01

    Full Text Available Amy Z Fan1, Jing Fang1, Ajay Yesupriya2, Man-huei Chang2, Greta Kilmer1, Meaghan House3, Donald Hayes1, Renée M Ned2, Nicole F Dowling2, Ali H Mokdad1 1National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA; 2Office of Public Health Genomics, Coordinating Center for Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA; 3School of Public Health, Emory University, Atlanta, GA, USAPurpose: Epidemiologic studies suggest that several gene variants increase the risk of stroke, and population-based studies help provide further evidence. We identified polymorphisms associated with the prevalence of self-reported stroke in US populations using a representative sample.Methods: Our sample comprised US adults in the Third National Health and Nutrition Examination (NHANES III DNA bank. We examined nine candidate gene variants within ACE, F2, F5, ITGA2, MTHFR, and NOS3 for associations with self-reported stroke. We used multivariate regression and Cox proportional hazards models to test the association between these variants and history of stroke.Results: In regression models, the rs4646994 variant of ACE (I/I and I/D genotypes was associated with higher prevalence adjusted prevalence odds ratio [APOR] = 2.66 [1.28, 5.55] and 2.23 [1.30, 3.85], respectively compared with the D/D genotype. The heterozygous genotype of MTHFR rs1801131 (A/C was associated with lower prevalence of stroke (APOR = 0.48 [0.25, 0.92] compared with A/A and C/C genotypes. For rs2070744 of NOS3, both the C/T genotype (APOR = 1.91 [1.12, 3.27] and C/C genotype (APOR = 3.31 [1.66, 6.60] were associated with higher prevalence of stroke compared with the T/T genotype.Conclusion: Our findings suggest an association between the prevalence of self-reported stroke and polymorphisms in ACE, MTHFR, and NOS3 in a population-based sample. Keywords: stroke, gene, polymorphisms, NHANES III, gene

  9. Augmented reality application utility for aviation maintenance work instruction

    Science.gov (United States)

    Pourcho, John Bryan

    Current aviation maintenance work instructions do not display information effectively enough to prevent costly errors and safety concerns. Aircraft are complex assemblies of highly interrelated components that confound troubleshooting and can make the maintenance procedure difficult (Drury & Gramopadhye, 2001). The sophisticated nature of aircraft maintenance necessitates a revolutionized training intervention for aviation maintenance technicians (United States General Accounting Office, 2003). Quite simply, the paper based job task cards fall short of offering rapid access to technical data and the system or component visualization necessary for working on complex integrated aircraft systems. Possible solutions to this problem include upgraded standards for paper based task cards and the use of integrated 3D product definition used on various mobile platforms (Ropp, Thomas, Lee, Broyles, Lewin, Andreychek, & Nicol, 2013). Previous studies have shown that incorporation of 3D graphics in work instructions allow the user to more efficiently and accurately interpret maintenance information (Jackson & Batstone, 2008). For aircraft maintenance workers, the use of mobile 3D model-based task cards could make current paper task card standards obsolete with their ability to deliver relevant, synchronized information to and from the hangar. Unlike previous versions of 3D model-based definition task cards and paper task cards, which are currently used in the maintenance industry, 3D model based definition task cards have the potential to be more mobile and accessible. Utilizing augmented reality applications on mobile devices to seamlessly deliver 3D product definition on mobile devices could increase the efficiency, accuracy, and reduce the mental workload for technicians when performing maintenance tasks (Macchiarella, 2004). This proposal will serve as a literary review of the aviation maintenance industry, the spatial ability of maintenance technicians, and benefits of

  10. Applied Horizontal and Vertical Geothermal Heat Exchanger with Heat Pump System to Provide Air Conditioning for an Academic Facility in Mexico

    Directory of Open Access Journals (Sweden)

    Daniel Alcantar Martínez

    2017-07-01

    Full Text Available At present in Mexico, the renewable energy has become more important due to the great dependence of the country for fossil fuels. Within the several applications of renewable energy, there are the geothermal applications for the air conditioning of spaces. This technology employs heat pumps that interexchange heat with the ground. This technology is relatively young in Mexico, leaving a large field for study and application throughout the country. In this way, to calculate the correct sizing of geothermal heat exchangers, it is necessary to calculate the thermal loads of the complex in which this technology of geothermal heat pumps using vertical heat exchangers type U will be installed, to perform the calculation of thermal loads Autodesk Revit® software was used, with which was possible to make a virtual model in detail of the botanical center that is located in Morelia, Michoacán, Mexico and belongs to the Universidad Michoacana de San Nicolás de Hidalgo (UMNSH. This study shows the results of the analysis of the installations and determination of the thermal loads of the complex due to this type of infrastructure. By obtaining the values of the thermal loads, the dimensioning of the heat exchanger was archived, which will have to be installed to cover the thermal requirement of this system and his installation, in addition to the selection of the heat pump. This complex of 2 levels, where, on the first floor there are cubicles and laboratories and on the second floor, several common areas. The design was developed in detail in Autodesk Revit 2015. After obtaining the thermal loads, the GLHEPro software was used for dimensioning the Vertical heat exchangers with the number and depth of the exchangers was obtained. the GLD 2014 software was used for dimensioning the Horizontal heat exchangers with the number and depth of the exchangers was obtained.

  11. Theoretical Investigations of Dielectric Breakdown in CO2: Implications for Atmospheric Discharges on Mars (and Venus)

    Science.gov (United States)

    Riousset, J. A.

    2017-12-01

    The detection of an atmospheric discharge in the Martian atmosphere by Ruf et al. [GRL, 36, L13202, 2009] supports the idea of a Martian atmospheric electric circuit [Farrell and Desch, JGR, 106, E4, 2001]. However, the lack of subsequent detection of similar events raises the question of the conditions of their initiation, and the existence of Martian lightning remains a controversial question. On Earth, atmospheric electricity manifests itself in the form of glow, corona, streamer, and leader discharges observed as Saint Elmo's fire, sprites, lightning and jets discharges, and other Transient Luminous Events (TLEs). All of these are dielectric breakdown governed by different physics. Their initiation is associated with the crossing of specific electric field thresholds: relativistic runaway, streamer propagation, conventional breakdown, or thermal runaway thresholds, some better understood than others. For example, the initiation of a lightning discharge is known to occur when the local electric field exceeds a value similar to relativistic runaway field, but the exact threshold, as well as the physical mechanisms at work, remain unclear to date. Scaling laws for electric fields (and other quantities) have been established by Pasko et al. [GRL, 25(12), 2123-2126, 1998] and Pasko [NATO Sci. Series, Springer, 253-311, 2006]. In this work, we develop profiles for initiation criteria in air and in other atmospheric environments. We further calculate their associated scaling laws to determine the ability to trigger lightning flashes and TLEs on Mars. This lets us predict the likelihood of electrical discharges and calculate the expected electric field conditions, under which discharges could be observed. We develop the analogy between Earth sand storm [Nicoll et al., Env. Res. Lett., 6, 014001, 2001] and Martian dust storms [Melnik and Parrot, JGR, 103(A12), 1998] to investigate the charge structure and resulting electric fields necessary to initiate dielectric

  12. Neuropsychological phenotype of a patient with a de novo 970 kb interstitial deletion in the distal 16p11.2 region

    Directory of Open Access Journals (Sweden)

    Egger JI

    2014-03-01

    Full Text Available Jos I M Egger,1–3 Willem M A Verhoeven,1,4 Wim Verbeeck,5 Nicole de Leeuw61Vincent van Gogh Institute for Psychiatry, Centre of Excellence for Neuropsychiatry, Venray, the Netherlands; 2Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, the Netherlands; 3Behavioural Science Institute, Radboud University Nijmegen, Nijmegen, the Netherlands; 4Erasmus University Medical Centre, Department of Psychiatry, Rotterdam, the Netherlands; 5Vincent van Gogh Institute for Psychiatry, Centre for Autism and ADHD, Venray, the Netherlands; 6Department of Human Genetics, Radboud University Medical Centre, Nijmegen, the NetherlandsAbstract: The 16p11.2 microdeletion syndrome is characterized by a wide range of phenotypic expressions and is frequently associated with developmental delay, symptoms from the autism spectrum, epilepsy, congenital anomalies, and obesity. These phenotypes are often related to a proximal 16p11.2 deletion of approximately 600 kb (BP4–BP5 that includes the SH2B1 gene that is reported to be causative for morbid obesity. This more centromeric deletion is most strongly related to autism spectrum susceptibility and is functionally different from the more distal 16p12.2p11.2 region, which includes the so-called atypical 16p11.2 BP2–BP3 deletion (approximately 220 kb presenting with developmental delay, behavioral problems and mild facial dysmorphisms. Here, an adult male with a long history of maladaptive behaviors is described who was referred for diagnostic assessment of his amotivational features. Extensive neuropsychological examination demonstrated rigid thinking, anxious beliefs, and ideas of reference in the presence of normal intelligence. Microarray analysis demonstrated a de novo 970 kb 16p11.2 BP1–BP4 microdeletion that can be regarded as explanatory for his behavioral profile. It is concluded that microdeletion syndromes are not exclusively related to intellectual disabilities and

  13. Synthesis, characterization, and in vitro activity against Candida spp. of fluconazole encapsulated on cationic and conventional nanoparticles of poly(lactic-co-glycolic acid

    Directory of Open Access Journals (Sweden)

    Gómez-Sequeda N

    2017-05-01

    Full Text Available Nicolás Gómez-Sequeda,1 Rodrigo Torres,2 Claudia Ortiz3 1School of Biology, 2School of Chemistry, Faculty of Sciences, 3School of Microbiology, Faculty of Health, Universidad Industrial de Santander, Bucaramanga, Santander, Colombia Abstract: In this study, nanoparticles (NPs of poly(lactic-co-glycolic acid (PLGA loaded with fluconazole (FLZ and FLZ-NPs coated with the cationic polymer polyethylenimine (PEI (FLZ-NP-PEI were synthetized in order to improve antimycotic activity against four strains of Candida spp. of clinical relevance. FLZ-NPs and FLZ-NP-PEI were synthesized by double emulsion solvent-diffusion (DES-D and characterized. Minimum inhibitory concentration (MIC50 and minimum fungicide concentration (MFC were determined in vitro by culturing Candida strains in the presence of these nanocompounds. FLZ-NPs were spherical in shape with hydrodynamic sizes of ~222 nm and surface charge of -11.6 mV. The surface charges of these NPs were successfully modified using PEI (FLZ-NP-PEI with mean hydrodynamic sizes of 281 nm and surface charge of 23.5 mV. The efficiency of encapsulation (~53% and a quick release of FLZ (≥90% after 3 h were obtained. Cytotoxicity assay showed a good cell viability for FLZ-NPs (≥86%, and PEI-modified NPs presented a decrease in cell viability (~38%. FLZ-NPs showed an increasing antifungal activity of FLZ for sensitive (Candida parapsilosis ATCC22019 and Candida albicans ATCC10231, MIC50 =0.5 and 0.1 µg/mL, respectively and resistant strains (Candida glabrata EMLM14 and Candida krusei ATCC6258, MIC50 =0.1 and 0.5 µg/mL, respectively. FLZ-NP-PEI showed fungicidal activity even against C. glabrata and C. krusei (MFC =4 and 8 µg/mL, respectively. MIC50 values showed best results for FLZ-NPs and FLZ-NP-PEI. Nevertheless, only FLZ-NP-PEI displayed fungicidal activity against the studied strains. Keywords: drug delivery systems, double emulsion diffusion, nanoparticles, minimal inhibitory concentration

  14. COMMUNICATION: On variability and use of rat primary motor cortex responses in behavioral task discrimination

    Science.gov (United States)

    Jensen, Winnie; Rousche, Patrick J.

    2006-03-01

    The success of a cortical motor neuroprosthetic system will rely on the system's ability to effectively execute complex motor tasks in a changing environment. Invasive, intra-cortical electrodes have been successfully used to predict joint movement and grip force of a robotic arm/hand with a non-human primate (Chapin J K, Moxon K A, Markowitz R S and Nicolelis M A L 1999 Real-time control of a robotic arm using simultaneously recorded neurons in the motor cortex Nat. Neurosci. 2 664-70). It is well known that cortical encoding occurs with a high degree of cortical plasticity and depends on both the functional and behavioral context. Questions on the expected robustness of future motor prosthesis systems therefore still remain. The objective of the present work was to study the effect of minor changes in functional movement strategies on the M1 encoding. We compared the M1 encoding in freely moving, non-constrained animals that performed two similar behavioral tasks with the same end-goal, and investigated if these behavioral tasks could be discriminated based on the M1 recordings. The rats depressed a response paddle either with a set of restrictive bars ('WB') or without the bars ('WOB') placed in front of the paddle. The WB task required changes in the motor strategy to complete the paddle press and resulted in highly stereotyped movements, whereas in the WOB task the movement strategy was not restricted. Neural population activity was recorded from 16-channel micro-wire arrays and data up to 200 ms before a paddle hit were analyzed off-line. The analysis showed a significant neural firing difference between the two similar WB and WOB tasks, and using principal component analysis it was possible to distinguish between the two tasks with a best classification at 76.6%. While the results are dependent upon a small, randomly sampled neural population, they indicate that information about similar behavioral tasks may be extracted from M1 based on relatively few

  15. Boys starting school disadvantaged: implications from teachers' ratings of behaviour and achievement in the first two years.

    Science.gov (United States)

    Childs, G; McKay, M

    2001-06-01

    Consistent evidence indicates that low socio-economic status (SES) acts as an important stressor and vulnerability factor for children's school learning. However, specific mechanism(s) of this process are still not well understood. This study was a follow-up of the classroom learning behaviour and perceived achievement of low and middle income children after two years at school, who had previously been rated soon after starting school. It examined whether teachers' ratings displayed predictive stability over that period, and whether significant differences evident at age 5 in SES and gender were still operative at age 7. Two samples, of low income (N = 85) and middle income (N = 63) children, were rated following school entry (mean age 5 years 3 months) and rated again after two years at school. The children were rated at both points by their regular classroom teachers using the Learning Behaviours Scale (Stott et al., 1998) with subscales of Distractible, Apprehensive and Uncooperative, together with ratings of academic achievement and their personal perception of each child. SES was found to be a very limited predictor for the learning behaviour subscale ratings and for teachers' personal perceptions at both ages 5 and 7. SES did significantly predict expected Academic Achievement at age 5, but this effect disappeared completely by age 7. Conversely, within the two defined groups, Low Income boys were found to display significantly poorer learning behaviours at age 5, especially in terms of distractible behaviour, compared with Middle Income boys and with girls generally. This pattern was maintained over the next two years of their schooling. The effect of SES was thus demonstrated more powerfully in between-group differences than by means of regression. The findings emphasised the persistence of teachers' initial negative impressions about distractible 'hard to manage' boys from low SES families. The outcomes of this study suggest that low SES boys commenced

  16. Effects of ionizing radiation over the structure, metabolism and infectivity of a pathogenic protozoan, Toxoplasma gondii; Efeitos da radiacao ionizante sobre a estrutura, metabolismo e infectividade de um protozoario patogenico, Toxoplasma gondii (Nicole and Manceau, 1908)

    Energy Technology Data Exchange (ETDEWEB)

    Hiramoto, Roberto Mitsuyoshi

    1998-07-01

    The intracellular parasite Toxoplasma gondii (Apicomplexa), has as definitive host domestic and wild felines and as intermediate hosts most species of mammals and birds, Including man. The infection in man is usually asymptomatic, but can become a severe and lethal illness in some special groups like the fetus of primoinfected pregnant woman, or in AIDS and transplanted patients. The transmission is due to ingestion of food or water contaminated with oocysts from cat feces as well as raw or rare cooked cyst containing meet. There is no available vaccine against toxoplasmosis, with some reports of the use ionizing radiation in order to attenuate or suppress the parasite. These studies are promising, but more research is needed to optimize the radiation process and to clarify those alterations caused on T gondii.Using a increasing doses of {sup 60} Co irradiation on T.gondii tachyzoites, we studied many parameters such as morphology, both at optical and electron microscopy level, detection of DNA fragmentation, metabolism alterations (cellular oxidative burst, protein, nucleic acids and DNA synthesis), determination of the parasite survival both in in vivo and in vitro models, antigenicity and immunogenicity after the process, cellular invasion and irradiated tachyzoite induced protection. After definition of 200 Gy of {sup 60} Co irradiation as the lower radiation dose that suppress parasite growth in vitro and in vivo, we found no detectable changes in parasite viability, its cell invasion capacity or in its structural proteins. DNA fragmentation like apoptosis or alterations of the parasite metabolism were similarly not affected by radiation. Mice infection with irradiated parasites induce partial protection when these animals were re-inoculated with non irradiated virulent parasites, inducing greater specific IgG levels as well as a longer survival. Irradiated T.gondii maintains its the ability of invasion, even under radiation effects. Based on our results we conclude that ionizing radiation can be considered as a possible tool in vaccine production due to similar viability, invasivity and metabolism and absence of reproductive capacity, of irradiated tachyzoites. (author)

  17. Il manoscritto miniato Collectanea del cardinale Nicolás Rossell dell´Archivio Vaticano Arm. XXXV, 70. Contributo sulla questione dell´attivita dei miniaturisti boemi alla corte degli antipapi avignonesi Clemente VII e Benedetto XIII

    Czech Academy of Sciences Publication Activity Database

    Studničková, Milada

    2008-01-01

    Roč. 6, - (2008), s. 73-90 ISSN 1214-9438 R&D Projects: GA AV ČR IAA8033202 Institutional research plan: CEZ:AV0Z80330511 Keywords : Czech book illumination * Avignon book illumination * master of the missal of Klement VII * Vatican archive * Holkham Hall Subject RIV: AL - Art, Architecture, Cultural Heritage

  18. Nicole Auferkorte-Michaelis, Ingeborg Stahr, Anette Schönborn, Ingrid Fitzek (Hg.: Gender als Indikator für gute Lehre. Erkenntnisse, Konzepte und Ideen für die Hochschule. Opladen u.a.: Budrich UniPress 2009.

    Directory of Open Access Journals (Sweden)

    Ilse Costas

    2011-03-01

    Full Text Available Der vorliegende Sammelband enthält Beiträge zu drei Schwerpunkten: Es geht erstens um hochschulweite Konzepte der Personal- und Organisationsentwicklung, gemessen an dem Prüfstein Gender Mainstreaming, zweitens um Ergebnisse der Lehr- und Lernforschung unter gendersensibler Perspektive und drittens um Genderaspekte und Genderkompetenz im Lehr- und Lernalltag. Die Einzelergebnisse bieten eine gute Orientierung; auf der theoretischen und konzeptionellen Ebene der Geschlechterforschung und der Geschlechterpolitik in der Hochschule ist jedoch kritisch anzumerken, dass unterschiedlichen Traditionen folgende Genderbegriffe und politische Strategien unvermittelt zusammengestellt werden, ohne deren Genealogien und politischen Kontexte zu reflektieren. Dies trifft besonders auf das Konzept des Gender Diversity Managements zu. Nicht einbezogen wird außerdem der internationale Forschungsstand zu den neuen Steuerungsformen in Hochschule und Wissenschaft insbesondere im Hinblick auf Prozesse des doing gender.This anthology contains articles about three main topics: first, university-wide concepts for human resource and organizational development regarding the touchstone gender mainstreaming; second, findings of teaching and learning research from a gender-sensitive perspective; and third, gender aspects and gender competence in the everyday life of teaching and learning. The individual findings offer a good orientation; however, regarding the theoretical and conceptual level of gender research and gender politics at the universities, it has to be noted critically that gender concepts and political strategies from varying traditions are put together abruptly without reflecting on their genealogies and political contexts. This is particularly true for the concept of gender diversity management. Furthermore, the international state of research regarding new forms of regulation in university and science, particularly considering processes of doing gender, is ignored.

  19. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2004-01-01

    search for home. Durham NC: Duke University Press, 2001. x + 324 pp., Georges Eugene Fouron (eds -Karen Fog Olwig, Nancy Foner, From Ellis Island to JFK: New York's two great waves of immigration. Chelsea MI: Russell Sage Foundation, 2000. xvi + 334 pp. -Aviva Chomsky, Lara Putnam, The company they kept: Migrants and the politics of gender in Caribbean Costa Rica, 1870-1960. Chapel Hill: University of North Carolina Press, 2002. xi + 303 pp. -Rebecca B. Bateman, Rosalyn Howard, Black Seminoles in the Bahamas. Gainesville: University Press of Florida, 2002. xvii + 150 pp. -Virginia Kerns, Carel Roessingh, The Belizean Garífuna: Organization of identity in an ethnic community in Central America. Amsterdam: Rozenberg. 2001. 264 pp. -Nicole Roberts, Susanna Regazzoni, Cuba: una literatura sin fronteras / Cuba: A literature beyond boundaries. Madrid: Iberoamericana/Frankfurt am Main, Germany: Vervuert, 2001. 148 pp. -Nicole Roberts, Lisa Sánchez González, Boricua literature: A literary history of the Puerto Rican Diaspora. New York: New York University Press, 2001. viii + 216 pp. -Kathleen Gyssels, Ange-Séverin Malanda, Passages II: Histoire et pouvoir dans la littérature antillo-guyanaise. Paris: Editions du Ciref, 2002. 245 pp. -Sue N. Greene, Simone A. James Alexander, Mother imagery in the novels of Afro-Caribbean women. Columbia MO: University of Missouri Press, 2001. x + 215 pp. -Gert Oostindie, Aarón Gamaliel Ramos ,Islands at the crossroads: Politics in the non-independent Caribbean., Angel Israel Rivera (eds -Katherine E. Browne, David A.B. Murray, Opacity: Gender, sexuality, race, and the 'problem' of identity in Martinique. New York: Peter Lang, 2002. xi + 188 pp. -James Houk, Kean Gibson, Comfa religion and Creole language in a Caribbean community. Albany: State University of New York Press, 2001. xvii + 243 pp. -Kelvin Singh, Frank J. Korom, Hosay Trinidad: Muharram performances in an Indo-Caribbean Diaspora.Philadelphia: University of

  20. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2001-07-01

    societies of color in the nineteenth century. Baton Rouge: Louisiana State University Press, 1998. xxii + 227 pp. -Alvin O. Thompson, Maurice St. Pierre, Anatomy of resistance: Anti-colonialism in Guyana 1823-1966. London: Macmillan, 1999. x + 214 pp. -Linda Peake, Barry Munslow, Guyana: Microcosm of sustainable development challenges. Aldershot, U.K. and Brookfield VT: Ashgate, 1998. x + 130 pp. -Stephen Stuempfle, Peter Mason, Bacchanal! The carnival culture of Trinidad. Philadelphia PA: Temple University Press, 1998. 191 pp. -Christine Chivallon, Catherine Benoît, Corps, jardins, mémoires: Anthropologie du corps et de l' espace à la Guadeloupe. Paris: CNRS Éditions, 2000. 309 pp. -Katherine E. Browne, Mary C. Waters, Black identities: Wsst Indian immigrant dreams and American realities. New York: Russell Sage Foundation; Cambridge MA: Harvard University Press, 1999. xvii + 413 pp. -Eric Paul Roorda, Bernardo Vega, Los Estados Unidos y Trujillo - Los días finales: 1960-61. Colección de documentos del Departamento de Estado, la CIA y los archivos del Palacio Nacional Dominicano. Santo Domingo: Fundación Cultural Dominicana, 1999. xx+ 783 pp. -Javier Figueroa-de Cárdenas, Charles D. Ameringer, The Cuban democratic experience: The Auténtico years, 1944-1952. Gainesville: University Press of Florida, 2000. ix + 230 pp. -Robert Lawless, Charles T. Williamson, The U.S. Naval mission to Haiti, 1959-1963. Annapolis MD: Naval Institute Press, 1999. xv + 395 pp. -Noel Leo Erskine, Arthur Charles Dayfoot, The shaping of the West Indian Church, 1492-1962. Kingston: The Press University of the West Indies; Gainesville: University Press of Florida, 1999. xvii + 360 pp. -Edward Baugh, Laurence A. Breiner, An introduction to West Indian poetry. Cambridge: Cambridge University Press, 1998. xxii + 261 pp. -Lydie Moudileno, Heather Hathaway, Caribbean waves: Relocating Claude McKay and Paule Marshall. Bloomington: Indiana University Press, 1999. xi + 201 pp. -Nicole Roberts

  1. Plant-derived pectin nanocoatings to prevent inflammatory cellular response of osteoblasts following Porphyromonas gingivalis infection

    Directory of Open Access Journals (Sweden)

    Meresta A

    2017-01-01

    Full Text Available Anna Meresta,1 Justyna Folkert,1 Timo Gaber,2 Korneliusz Miksch,1 Frank Buttgereit,2 Jacqueline Detert,2 Nicole Pischon,3,* Katarzyna Gurzawska3,4,* 1Environmental Biotechnology Department, Faculty of Power and Environmental, Silesian University of Technology, Gliwice, Poland; 2Department of Rheumatology and Clinical Immunology, 3Department of Periodontology, Charité University Medicine, Berlin, Germany; 4Oral Surgery Department, The School of Dentistry, University of Birmingham, Birmingham, UK *These authors contributed equally to this work Background: Bioengineered plant-derived Rhamnogalacturonan-Is (RG-Is from pectins are potential candidates for surface nanocoating of medical devices. It has recently been reported that RG-I nanocoatings may prevent bacterial infection and improve the biocompatibility of implants. The aim of the study was to evaluate in vitro impact of bioengineered RG-I nanocoatings on osteogenic capacity and proinflammatory cytokine response of murine osteoblasts following Porphyromonas gingivalis infection.Methods: Murine MC3T3-E1 osteoblasts and isolated primary calvarial osteoblasts from C57BL/6J (B6J osteoblasts mice were infected with P. gingivalis and incubated on tissue culture polystyrene plates with or without nanocoatings of unmodified RG-Is isolated from potato pulps (PU or dearabinanated RG-Is (PA. To investigate a behavior of infected osteoblasts cultured on RG-Is cell morphology, proliferation, metabolic activity, mineralization and osteogenic and pro-inflammatory gene expression were examined.Results: Following P. gingivalis infection, PA, but not PU, significantly promoted MC3T3-E1 and BJ6 osteoblasts proliferation, metabolic activity, and calcium deposition. Moreover, Il-1b, Il-6, TNF-α, and Rankl gene expressions were downregulated in cells cultured on PU and to a higher extent on PA as compared to the corresponding control, whereas Runx, Alpl, Col1a1, and Bglap gene expressions were upregulated vice

  2. The Darwinian revolution La revolución darwiniana

    Directory of Open Access Journals (Sweden)

    ÓSCAR M CHAVES

    2010-06-01

    Full Text Available The scientific revolution probably began at 16th century with the heliocentric theory of the eminent astronomer Nicolaus Copernicus, but it was culminated with the masterful discoveries of Galileo Galilei and Isaac Newton at 17th century who revealed that planet movements around the sun and other similar phenomena can be explained by simple mechanical laws of physics and astronomy. However, the origin, complexity and configuration of living beings remained in the mystery until 19th century, with the publication of "On the origin of species". In this essay I discuss the importance of the Darwinian scientific revolution, its beginnings, and the main objections of creationists to his evolutionary ideas. Darwin demonstrated that the origin and complexity of living beings can be explained by natural processes, without the intervention of a supernatural being. However, the beginnings of the Darwinian revolution were particularly difficult and 128 years after his death, the controversy between evolutionists and creationists still persists.Con base en la teoría heliocéntrica formulada por Nicolás Copérnico en el siglo XVI, Galileo Galilei e Isaac Newton iniciaron la revolución científica al demostrar que los movimientos de los planetas alrededor del sol podían ser explicados por las leyes de la física y la astronomía. No obstante, el origen y complejidad del mundo orgánico permaneció en el misterio hasta mediados del siglo XIX, cuando Charles Darwin publicó su célebre obra 'El origen de las especies'. Desde entonces, la selección natural se ha convertido en una de las teorías científicas más umversalmente aceptadas y Darwin en el fundador de la biología moderna. En este ensayo se discute la importancia de la revolución darwiniana, sus inicios y las principales objeciones de sus detractores. Darwin demostró que el origen y la complejidad de los seres vivos pueden ser explicados por procesos naturales sin necesidad de la intervenci

  3. Peak oxygen uptake and left ventricular ejection fraction, but not depressive symptoms, are associated with cognitive impairment in patients with chronic heart failure

    Directory of Open Access Journals (Sweden)

    Steinberg G

    2011-12-01

    Full Text Available Gerrit Steinberg1,2*, Nicole Lossnitzer2*, Dieter Schellberg2, Thomas Mueller-Tasch2, Carsten Krueger3, Markus Haass4, Karl Heinz Ladwig5, Wolfgang Herzog2, Jana Juenger21University Hospital of Psychiatry, University of Bern, Bern, Switzerland; 2Department of Psychosomatic and General Internal Medicine, Medical Hospital, University of Heidelberg, Heidelberg, 3Department of Cardiology, Josefs Hospital, Heidelberg, 4Department of Cardiology, Theresien Hospital, Mannheim, 5Institute of Epidemiology, German Research Center for Environmental Health, Munich, Germany*both authors contributed equally to this paperBackground: The aim of the present study was to assess cognitive impairment in patients with chronic heart failure (CHF and its associations with depressive symptoms and somatic indicators of illness severity, which is a matter of controversy.Methods and results: Fifty-five patients with CHF (mean age 55.3 ± 7.8 years; 80% male; New York Heart Association functional class I–III underwent assessment with an expanded neuropsychological test battery (eg, memory, complex attention, mental flexibility, psychomotor speed to evaluate objective and subjective cognitive impairment. Depressive symptoms were assessed using the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (SCID and a self-report inventory (Hospital Anxiety and Depression Scale [HADS]. A comprehensive clinical dataset, including left ventricular ejection fraction, peak oxygen uptake, and a 6-minute walk test, was obtained for all patients. Neuropsychological functioning revealed impairment in 56% of patients in at least one measure of our neuropsychological test battery. However, the Mini Mental State Examination (MMSE could only detect cognitive impairment in 1.8% of all patients, 24% had HADS scores indicating depressive symptoms, and 11.1% met SCID criteria for a depressive disorder. No significant association was found

  4. La firmeza del personal cubano de la salud en Venezuela. Nuestra opinión

    Directory of Open Access Journals (Sweden)

    José Suárez Lezcano

    2015-12-01

    Full Text Available La situación política y social en la hermana República Bolivariana de Venezuela en estos días es tensa. La oposición, encabezada por Henrique Capriles, se niega a reconocer el triunfo en las urnas del candidato socialista Nicolás Maduro. Capriles ha llamado a sus seguidores, de forma solapada, a no reconocer la victoria de Maduro, y ha estimulado actos de violencia en todo el país. Algunos centros médicos donde trabajan colaboradores cubanos no han escapado de esa violencia. Nuestros colaboradores, sin embargo, han seguido cumpliendo con su deber, por la razón que los llevó a la tierra de Bolívar: “atender a cada ciudadano venezolano que requiera de sus servicios, independientemente de la filiación política, clase social, u otras consideraciones,” como dijo al periódico Granma el viceministro cubano de Salud, Dr. Roberto González Martín. Pero nuestros hermanos cubanos no han estado solos. Se ha desarrollado un movimiento voluntario, espontáneo de protección entre los venezolanos, como muestra del cariño y respeto que se han ganado los profesionales cubanos entre los pobladores de los barrios populares. Se sabe, los venezolanos saben, que la presencia de los médicos, enfermeras y técnicos cubanos se debe únicamente  a dos nobles objetivos, el de brindar atención médica a todo el que lo necesite y el contribuir a la formación de médicos venezolanos, que ya en cifra de cerca de 15 mil se han graduado con la ayuda de los profesionales cubanos. Actualmente Cuba mantiene en Venezuela cerca de  45 mil colaboradores que brindan asistencia en las áreas de medicina, deportes, cultura, construcción, agricultura y otras, como parte de los programas de colaboración, impulsados por el fallecido Comandante presidente Hugo Chávez. Somos cubanos y conocemos bien el espíritu de nuestros compatriotas. El pueblo venezolano puede tener la certeza que nuestros profesionales de la salud estarán firmes, junto a ellos, mientras el

  5. A randomized, double-masked study to evaluate the effect of omega-3 fatty acids supplementation in meibomian gland dysfunction

    Directory of Open Access Journals (Sweden)

    Oleñik A

    2013-08-01

    Full Text Available Andrea Oleñik,1 Ignacio Jiménez-Alfaro,1 Nicolás Alejandre-Alba,1 Ignacio Mahillo-Fernández2 1Department of Ophthalmology, Jiménez Díaz Foundation, Madrid, Spain; 2Department of Statistics, Jiménez Díaz Foundation, Madrid, Spain Background: Dysfunction of the meibomian gland (MG is among the most frequent causes of ophthalmological symptoms. The inflammation seen in meibomian gland dysfunction (MGD is part of its pathogenesis, and evidence of the antioxidant-inflammatory properties of omega-3 fatty acids suggests this to be an appropriate treatment for MGD. Objective: We aimed to assess the effectiveness of omega-3 fatty acids versus placebo, in improving the symptoms and signs of MGD. Methods: We conducted a randomized and double-mask trial of 3 months duration. We enrolled 61 patients who presented with symptomatic MGD and no tear instability (defined as tear breakup time [TBUT] <10 seconds. Participants were randomly assigned to two homogeneous subgroups. For patients in group A, the study treatment included cleaning the lid margins with neutral baby shampoo and use of artificial tears without preservatives, plus a placebo oral agent. For patients in group B, the study treatment included cleaning the lid margins with neutral baby shampoo and use of artificial tears without preservatives, plus oral supplementation with omega-3 fatty acids. We performed the following tests: (1 TBUT; (2 Schirmer I test; (3 Ocular Surface Disease Index© (OSDI©; Allergan, Inc., Irvine, CA, USA; (4 MG expression; (5 evaluation of lid margin inflammation; and (6 interpalpebral and corneal dye staining. Results: After 3 months of evaluation, the mean OSDI, TBUT, lid margin inflammation, and MG expression presented improvement from the baseline values, in group B (P < 0.01, P < 0.001, P < 0.0001, P < 0.0001, respectively. The Schirmer test results were also improved and statistically significant (P < 0.01. Conclusion: Oral omega-3 fatty acids, 1.5 grams per

  6. Epidémie de choléra au Burkina Faso en 2005: aspects épidémiologiques et diagnostiques

    Directory of Open Access Journals (Sweden)

    Carole Gilberte Kyelem

    2011-01-01

    Full Text Available INTRODUCTION: L’objectif de cette étude était de décrire les aspects épidémiologiques et diagnostiques de l’épidémie de choléra au Burkina Faso en 2005. METHODES: Etude rétrospective, d’août à octobre 2005. Elle a concerné dix districts sanitaires du Burkina Faso. A été inclus dans l’étude, tout patient présentant un syndrome cholériforme, admis dans les différentes formations sanitaires dont la coproculture s’est révélée positive à Vibrio cholerae. RESULTATS: Au cours cette épidémie, 1050 cas de diarrhées cholériformes ont été notifiés par l’ensemble des structures sanitaires du pays. Vibrio cholerae a été identifié à l’examen bactériologique des selles de 121 patients (17,2%, constituant notre population d’étude. Les hommes étaient majoritaires (57%. La moyenne d’âge était de 30 ans. Les femmes au foyer (24% et les sujets non scolarisés (62,8% représentaient les couches sociales les plus touchées. Les forages ont été la source de boisson de 39,7% des patients 72 heures avant le début de la maladie. Tous les patients ont présenté une diarrhée aqueuse. Vibrio cholerae, sérotype Ogawa, responsable de cette épidémie, était résistant au chloramphénicol et au cotrimoxazole dans respectivement 71,7% et 38,3% des cas. Ni le cas index, ni la source initiale de contamination n’ont pu être identifiés. La létalité de notre échantillon était de 3,5%. CONCLUSION: Cette épidémie a relancé la question de l’hygiène et mis à nu le problème de ces villes ou la croissance démographique galopante est en inadéquation avec le degré d’urbanisation

  7. Art Públic i Memòria Ferroviària Regional (Sud-oest de Buenos Aires, República Argentina, 2003/2016

    Directory of Open Access Journals (Sweden)

    Diana I Ribas

    2017-07-01

    Full Text Available En els noranta, la degradació final del sistema ferroviari estatal impulsada pel president Carlos Menem en el marc d’una sèrie de normes neoliberals va implicar, paradoxalment, que es convertís en una atracció per a l’art públic regional. En aquest llavors, el Museu Municipal d’Art de Badia Blanca va impulsar un Simposi Nacional d’Escultura Monumental convidant a deu artistes a utilitzar la ferralla de ferro. Segons el paradigma modern d’art autònom, se’ls va trobar posteriorment un emplaçament en un parc lineal que va començar a ser anomenat Passeig de les Escultures. En aquest article s’aborda la segona etapa en tant vehicle de memòria. Al segle XXI, la utilització dels edificis abandonats amb fins culturals va ser paral·lela a un començament de reactivació ferroviària portada endavant pel kirchnerisme, no obstant els seus efectes no van ser sentits en aquesta regió. La creació del museu-taller Ferrowhite (2003, la presentació del projecte Intempèrie a la Biennal Regional d’Art el 2014 i les accions de l’Associació Amics de l’Estació Nicolás Levalle en aquest mateix any, han promogut una memòria que es debat entre la poesia de les ruïnes i la recuperació patrimonial. Aquestes propostes ubicades a llocs específics s’han recuperat els seus contextos històrics i teixit en ells entramats socials mitjançant pràctiques participatives i col·laboratives, creant les condicions de possibilitat perquè es generin picades d’ullet còmplices entre els integrants i es transformin en “llocs encantats” (de Certeau. Al seu torn, tenint en compte que es plantegen a si mateixes com a centres i les seves pràctiques emergents han estat produïdes des d’una ambigua frontera artístic-històric-polític-social, aquestes iniciatives de base comunitària poden ser caracteritzades com cartografies frontereres.

  8. Fluorescence resonance energy transfer-based real-time polymerase chain reaction method without DNA extraction for the genotyping of F5, F2, F12, MTHFR, and HFE

    Directory of Open Access Journals (Sweden)

    Martinez-Serra J

    2014-06-01

    Full Text Available Jordi Martinez-Serra,1 Juan Robles,2 Antoni Nicolàs,3 Antonio Gutierrez,1 Teresa Ros,1 Juan Carlos Amat,1 Regina Alemany,4 Oliver Vögler,4 Aina Abelló,2 Aina Noguera,2 Joan Besalduch1 1Department of Hematology, 2Department of Clinical Analysis, Hospital Universitary Son Espases, Palma de Mallorca, Spain; 3ECOGEN, Barcelona, 4Department of Cell Biology, University of the Balearic Islands, Palma de Mallorca, Spain Abstract: Blood samples are extensively used for the molecular diagnosis of many hematological diseases. The daily practice in a clinical laboratory of molecular diagnosis in hematology involves using a variety of techniques, based on the amplification of nucleic acids. Current methods for polymerase chain reaction (PCR use purified genomic DNA, mostly isolated from total peripheral blood cells or white blood cells (WBC. In this paper we describe a real-time fluorescence resonance energy transfer-based method for genotyping directly from blood cells. Our strategy is based on an initial isolation of the WBCs, allowing the removal of PCR inhibitors, such as the heme group, present in the erythrocytes. Once the erythrocytes have been lysed, in the LightCycler® 2.0 Instrument, we perform a real-time PCR followed by a melting curve analysis for different genes (Factors 2, 5, 12, MTHFR, and HFE. After testing 34 samples comparing the real-time crossing point (CP values between WBC (5×106 WBC/mL and purified DNA (20 ng/µL, the results for F5 Leiden were as follows: CP mean value for WBC was 29.26±0.566 versus purified DNA 24.79±0.56. Thus, when PCR was performed from WBC (5×106 WBC/mL instead of DNA (20 ng/µL, we observed a delay of about 4 cycles. These small differences in CP values were similar for all genes tested and did not significantly affect the subsequent analysis by melting curves. In both cases the fluorescence values were high enough, allowing a robust genotyping of all these genes without a previous DNA purification

  9. REAC regenerative treatment efficacy in experimental chondral lesions: a pilot study on ovine animal model

    Directory of Open Access Journals (Sweden)

    Sanna Passino E

    2017-09-01

    Full Text Available Eraldo Sanna Passino,1,2 Stefano Rocca,1 Sabrina Caggiu,1 Nicolò Columbano,1,2 Alessandro Castagna,3 Vania Fontani,3–5 Salvatore Rinaldi3–51Department of Veterinary Medicine, University of Sassari, Sassari, Italy; 2Comparative Surgery Research Laboratory, University of Sassari, Sassari, Italy; 3Department of Regenerative Medicine, Rinaldi Fontani Institute, Florence, Italy; 4Research Department, Rinaldi Fontani Foundation, Florence, Italy; 5Research Department, IRF Shanghai Biomedical Sciences, Shanghai, People’s Republic of China Abstract: Radioelectric asymmetric conveyor (REAC technology is a platform designed to optimize cell polarity. Cell polarity is a universal biological phenomenon that is implicated in cell differentiation, proliferation, morphogenesis, aging, and rejuvenation. In this work, we investigate a timing and administration protocol for tissue optimization regenerative treatment type C, in order to treat aging-related chondral damage or injuries and gain insights into regenerative processes of articular cartilage in humans. The chondral lesion produced in this study in an animal model (6 knee joints of 4 adult sheep was 6 mm in diameter and about 2 mm deep. These lesions, which did not involve subchondral bone, tend to increase in size and depth and are not completely repaired with normal hyaline articular cartilage since adult articular cartilage is avascular and has a very slow turnover at the cellular and molecular level. Moreover, the hydration of articular cartilage is reduced with aging and with decreased mitotic activity, synthesis, and population size of chondrocytes. Six months posttreatment, lesions appeared filled, though not completely, with newly generated tissue of the light opalescent color of healthy articular cartilage, which otherwise covered the underlying subchondral bone. The newly formed tissue surface appeared to be quite regular. Nearly complete regeneration of subchondral bone occurred, with

  10. A systematic review and meta-analysis of Harmonic technology compared with conventional techniques in mastectomy and breast-conserving surgery with lymphadenectomy for breast cancer

    Directory of Open Access Journals (Sweden)

    Cheng H

    2016-07-01

    Full Text Available Hang Cheng,1 Jeffrey W Clymer,1 Nicole C Ferko,2 Leena Patel,2 Ireena M Soleas,2 Chris G Cameron,2 Piet Hinoul1 1Ethicon Inc., Cincinnati, OH, USA; 2Cornerstone Research Group, Burlington, ON, Canada Background: Mastectomy and breast-conserving surgery (BCS are important treatment options for breast cancer patients. A previous meta-analysis demonstrated that the risk of certain complications can be reduced with the Harmonic technology compared with conventional methods in mastectomy. However, the meta-analysis did not include studies of BCS patients and focused on a subset of surgical complications. The objective of this study was to compare Harmonic technology and conventional techniques for a range of clinical outcomes and complications in both mastectomy and BCS patients, including axillary lymph node dissection.Methods: A comprehensive literature search was performed for randomized controlled trials comparing Harmonic technology and conventional methods in breast cancer surgery. Outcome measures included blood loss, drainage volume, total complications, seroma, necrosis, wound infections, ecchymosis, hematoma, hospital length of stay, and operating time. Risk of bias was analyzed for all studies. Meta-analysis was performed using random-effects models for mean differences of continuous variables and a fixed-effects model for risk ratios of dichotomous variables.Results: Twelve studies met the inclusion criteria. Across surgery types, compared to conventional techniques, Harmonic technology reduced total complications by 52% (P=0.002, seroma by 46% (P<0.0001, necrosis by 49% (P=0.04, postoperative chest wall drainage by 46% (P=0.0005, blood loss by 38% (P=0.0005, and length of stay by 22% (P=0.007. Although benefits generally appeared greatest in mastectomy patients with lymph node dissection, ­Harmonic technology showed significant reductions in complications in the BCS study subgroup.Conclusion: In this meta-analysis of both mastectomy and

  11. Self- and zinc diffusion in gallium antimonide

    International Nuclear Information System (INIS)

    Nicols, Samuel Piers

    2002-01-01

    )[Dvorak, (2001)]. Many of the findings which will be reported here were previously published in three journal articles. Hartmut Bracht was the lead author on two articles on self-diffusion studies in GaSb[Bracht, (2001), (2000)], while this report's author was the lead author on Zn diffusion results[Nicols, (2001)]. Much of the information contained herein can be found in those articles, but a more detailed treatment is presented here

  12. Influence of Species of Vesicular-Arbuscular Mycorrhizal Fungi and Phosphorus Nutrition on Growth, Development, and Mineral Nutrition of Potato (Solanum tuberosum L.).

    Science.gov (United States)

    McArthur, DAJ.; Knowles, N. R.

    1993-07-01

    Growth, development, and mineral physiology of potato (Solanum tuberosum L.) plants in response to infection by three species of vesicular-arbuscular mycorrhizal (VAM) fungi and different levels of P nutrition were characterized. P deficiency in no-P and low-P (0.5 mM) nonmycorrhizal plants developed between 28 and 84 d after planting. By 84 d after planting, P deficiency decreased plant relative growth rate such that no-P and low-P plants had, respectively, 65 and 45% less dry mass and 76 and 55% less total P than plants grown with high P (2.5 mM). A severe reduction in leaf area was also evident, because P deficiency induced a restriction of lateral bud growth and leaf expansion and, also, decreased the relative plant allocation of dry matter to leaf growth. Root growth was less influenced by P deficiency than either leaf or stem growth. Moreover, P-deficient plants accumulated a higher proportion of total available P than high-P plants, indicating that P stress had enhanced root efficiency of P acquisition. Plant P deficiency did not alter the shoot concentration of N, K, Mg, or Fe; however, the total accumulation of these mineral nutrients in shoots of P-stressed plants was substantially less than that of high-P plants. P uptake by roots was enhanced by each of the VAM symbionts by 56 d after planting and at all levels of abiotic P supply. Species differed in their ability to colonize roots and similarly to produce a plant growth response. In this regard, Glomus intraradices (Schenck and Smith) enhanced plant growth the most, whereas Glomus dimorphicum (Boyetchko and Tewari) was least effective, and Glomus mosseae ([Nicol. and Gerd.] Gerd. and Trappe) produced an intermediate growth response. The partial alleviation of P deficiency in no-P and low-P plants by VAM fungi stimulated uptake of N, K, Mg, Fe, and Zn. VAM fungi enhanced shoot concentrations of P, N, and Mg by 28 d after planting and, through a general improvement of overall plant mineral nutrition

  13. Juan of Segovia’s Translation of the Qur’ān

    Directory of Open Access Journals (Sweden)

    Roth, Ulli

    2014-12-01

    Full Text Available John of Segovia (1393-1458 is together with Nicolaus Cusanus one of the most important theologians of the 15th century. His struggle for peace and consensus during the council of Basel culminated in his engagement for interreligious communication in the last years of his life. After the fall of Constantinople in 1453, he prepared a new approach towards the Islam. Not crusade, but interreligious communication based on thorough knowledge of the religion of the other should result in peace, either through converting the other or at least convincing him to stop warfare. Therefore John of Segovia initiated a new translation of the Qur’ān into Spanish, which he himself translated into Latin. This article outlines the history of this famous project and illustrates its main characteristics with examples taken from fragments of this first polyglot translation of the Qur’ān.Junto a Nicolás de Cusa, Juan de Segovia (1393-1458 fue uno de los teólogos más importantes del siglo XV. Sus esfuerzos por llegar a una paz y a un consenso durante el concilio de Basilea culminaron con un compromiso de comunicación interreligiosa en los últimos años de su vida. Después de la caída de Constantinopla en el año 1453, preparó un nuevo acercamiento hacia el Islam. Ya no se trataba de una cruzada, sino de realizar una comunicación entre religiones basada en un conocimiento profundo de la religión del otro, lo que creía que resultaría en una paz a través de la conversión del otro o, al menos, a través del convencimiento de que dejaría la guerra. Juan de Segovia comenzó así la tarea de traducir de nuevo el Corán al castellano, que él mismo había traducido al latín. Este artículo muestra la historia de este famoso proyecto ilustrando sus características más llamativas con ejemplos tomados de esta primera traducción políglota del Corán.

  14. Correlation between MRI results and intraoperative findings in patients with silicone breast implants

    Directory of Open Access Journals (Sweden)

    Lindenblatt N

    2014-07-01

    Full Text Available Nicole Lindenblatt,1 Karem El-Rabadi,2 Thomas H Helbich,2 Heinrich Czembirek,3 Maria Deutinger,4 Heike Benditte-Klepetko5 1Division of Plastic and Hand Surgery, Department of Surgery, University Hospital Zurich, Zurich, Switzerland; 2Department of Biomedical Imaging and Image-guided Therapy, Division of Molecular and Gender Imaging, Medical University of Vienna - General Hospital Vienna, 3Department of Radiology, Hospital Wiener Privatklinik, 4Department of Plastic and Reconstructive Surgery, Hospital Rudolfstiftung, Vienna, Austria; 5Department of Plastic and Reconstructive Surgery, Erasmus Medical Center, Rotterdam, the Netherlands Background: Silicone gel breast implants may silently rupture without detection. This has been the main reason for magnetic resonance imaging (MRI of the augmented or reconstructed breast. The aim of the present study was to investigate the accuracy of MRI for implant rupture. Methods: Fifty consecutive patients with 85 silicone gel implants were included in the study. The mean age of the patients was 51 (range 21–72 years, with a mean duration of implantation of 3.8 (range 1–28 years. All patients underwent clinical examination and breast MRI. Intraoperative implant rupture was diagnosed by the operating surgeon. Results: Nineteen of the 50 patients suffered from clinical symptoms. An implant rupture was diagnosed by MRI in 22 of 85 implants (26%. In seven of 17 removed implants (41%, the intraoperative diagnosis corresponded with the positive MRI result. However, only 57% of these patients were symptomatic. Ultrasound imaging of the harvested implants showed signs of interrupted inner layers of the implant despite integrity of the outer shell. By microsurgical separation of the different layers of the implant shell, we were able to reproduce this phenomenon and to produce signs of implant rupture on MRI. Conclusion: Our results show that rupture of only the inner layers of the implant shell with integrity of

  15. Distribución de Aedes albopictus (Skuse en Nuevo León, México, 2001-2004 Distribution of Aedes albopictus (Skuse in Nuevo Leon, México, 2001-2004

    Directory of Open Access Journals (Sweden)

    Héctor Orta-Pesina

    2005-04-01

    Full Text Available OBJETIVO: Determinar la distribución de Aedes albopictus (Skuse en Nuevo León, México. MATERIAL Y MÉTODOS: Entre 2001 y 2004, utilizando métodos estandarizados de recolección de larvas de mosquitos, se analizaron 6 371 muestras, de 167 localidades. Se estimaron proporciones de muestras positivas de Ae. albopictus, por municipio, por año, utilizando Excel. RESULTADOS: Hubo 1 179 muestras positivas para larvas de Ae. albopictus distribuidas en 10 municipios: cinco localizados en la llanura costera del Golfo de México, con clima semicálido, subhúmedo y con lluvias casi todo el año (Allende, Montemorelos, Linares, General Terán y Santiago; otros, Sabinas Hidalgo y Cadereyta, se localizan en las grandes llanuras del norte de América, con clima cálido, semiseco y con lluvias poco frecuentes y, finalmente, Apodaca, San Nicolás y Escobedo en el área metropolitana de la ciudad de Monterrey. CONCLUSIONES: Hasta noviembre de 2004, el segundo vector de mayor importancia epidemiológica en el ciclo de la transmisión de Ae. albopictus a escala mundial se encontró en 10 municipios del estado de Nuevo León.OBJECTIVE: To determine the distribution of Aedes albopictus (Skuse in Nuevo Leon between 2001 and 2004. MATERIAL AND METHODS: Standardized methods were used to collect 6371 samples of mosquito's larvae from 167 sites. The proportions of samples positive for Ae. albopictus were obtained by municipality and year, using the software program Excel. RESULTS: There were 1 179 samples positive for Ae. albopictus. This species was distributed over 10 municipalities, as follows: Five on the Gulf of Mexico Coastal Plains, which predominantly have a semi-warm, sub-humid climate, and precipitations almost year round (Allende, Montemorelos, Linares, General Teran, and Santiago; two (Sabinas Hidalgo, and Cadereyta localized on the North American Great Plains, which have a warm, semiarid climate, and scarce precipitations. The final three were Apodaca

  16. Prevalence of COPD and respiratory symptoms associated with biomass smoke exposure in a suburban area

    Directory of Open Access Journals (Sweden)

    Ramírez-Venegas A

    2018-05-01

    Full Text Available Alejandra Ramírez-Venegas,1 Mónica Velázquez-Uncal,1 Rosaura Pérez-Hernández,2 Nicolás Eduardo Guzmán-Bouilloud,1 Ramcés Falfán-Valencia,3 María Eugenia Mayar-Maya,4 Adrian Aranda-Chávez,1 Raúl H Sansores5 1Tobacco Smoking and COPD Research Department, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City, Mexico; 2Research Department of Tobacco Smoking, Centro de Investigacion de Salud Poblacional, Instituto Nacional de Salud Pública, Cuernavaca, Mexico; 3HLA Laboratory, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City, Mexico; 4Medical Attention Department, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City, Mexico; 5Medica Sur Clinic & Foundation, Mexico City, Mexico Introduction: Biomass smoke exposure (BSE is a recognized cause of COPD particularly in rural areas. However, little research has been focused on BSE in suburban areas. Objective: The aim of this study was to determine the prevalence of COPD, respiratory symptoms (RS and BSE in women living in a suburban area of Mexico City exposed to BSE. Methods: A cross-sectional epidemiological survey of a female population aged >35 years was performed using a multistage cluster sampling strategy. The participants completed questionnaires on RS and COPD risk factors. The COPD prevalence was based on the postbronchodilator forced expiratory volume in the first second (FEV1/forced vital capacity (FVC ratio. Of the 1,333 women who completed the respiratory questionnaires, spirometry data were obtained from 1,190, and 969 of these were scored as A–C. Results: The prevalence of BSE was 47%, and the estimated prevalence of COPD was 2.5% for the total population (n=969 and 3.1% for those with BSE only. The spirometry and oximetry values were significantly lower in women with greater exposure levels. The prevalence of RS (cough, phlegm, wheezing and dyspnea was significantly higher in the

  17. Editorial, n. 12, 2001

    Directory of Open Access Journals (Sweden)

    Editor Encontros Bibli

    2001-01-01

    Full Text Available EDITORIAL, n. 12, 2001 Este número da Encontros Bibli apresenta diferentes abordagens de questões relativas à sociedade do conhecimento. Esta sociedade vem acompanhada de uma evolução tecnológica que afeta, em diferentes graus, todos os países do mundo, produzindo impactos de natureza econômica, política, social e cultural. Tais impactos necessitam de parâmetros para sua análise e avaliação. A medição de bens intangíveis, neste caso, provenientes do uso das tecnologias da informação e da comunicação, é uma tarefa complexa. O artigo do professor Michel Menou, da City University, de Londres, apresenta uma metodologia original para análise desses indicadores na sociedade atual. O relato de pesquisa da professora Clarice Fortkamp Caldin, do Departamento de Ciência da Informação da UFSC, aborda o processo de leitura como função terapêutica. Este trabalho é baseado na sua dissertação de mestrado e representa um foco de abordagem pouco usual na Ciência da Informação. O professor Francisco das Chagas de Souza, também do Departamento de Ciência da Informação da UFSC, apresenta uma análise de sua experiência no ensino de fundamentos teóricos da Biblioteconomia. A estudante Maria Elizabeth Horn Pepulim, do Curso de Biblioteconomia da UFSC, reflete sobre o papel do bibliotecário na sociedade da informação, ressaltando os dilemas, atribuições e responsabilidades deste profissional no mundo globalizado. Esta edição divulga ainda uma pesquisa sobre bibliotecas públicas, sociedade da informação e tecnologia, que está sendo desenvolvida pelos colegas do Instituto de Investigaciones Bibliotecológicas da Universidad de Buenos Aires: Elsa Barber, Nicolás Tripaldi, Silvia Pisano, Valeria Werner, Sofia D´Alessandro, Sandra Romagnoli, Verónica Parsiale, Carolina Gregui e Gabriela De Pedro. Miriam Vieira da Cunha, editora Disponibilizado na WWW em 28/12/2001. Enc. Bibli: R. Eletr. Bibliotecon. Ci. Inf., ISSN 1518

  18. The SWEET SPOTS study: a real-world interpretation of the 2012 American Diabetes Association Position Statement regarding individualized A1C targets

    Directory of Open Access Journals (Sweden)

    Bieszk N

    2016-11-01

    Full Text Available Nella Bieszk,1 Michael Grabner,2 Wenhui Wei,1 Nicole G Bonine,2 Judith J Stephenson,2 1Sanofi US, Inc., Bridgewater, NJ, 2HealthCore, Inc., Wilmington, DE, USA Objective: To evaluate awareness of the 2012 American Diabetes Association (ADA Position Statement among physicians and assess its effects on patient-centered glycated hemoglobin (A1C goals in the management of type 2 diabetes (T2D. Research design and methods: The Summarizing Real-World Individualized TrEatmEnT GoalS and Potential SuppOrT Systems in Type 2 Diabetes (SWEET SPOTS study used the HealthCore claims database to identify T2D patients, stratified by risk, and their treating physicians to assess primary care physician and endocrinologist awareness of the 2012 ADA Position Statement. Physicians completed online surveys on A1C targets before and after receiving an educational intervention to review the position statement. Results: Of 125 responding physicians (mean age 50.3 years, 12.8% endocrinologists who were linked to 125 patient profiles (mean age 56.9 years, 42% female, mean A1C 7.2%, 92% were at least somewhat aware of the position statement prior to the intervention and 59% believed that the statement would impact how they set A1C targets. The educational intervention resulted in mostly less stringent goal setting for both lower and higher risk patients, but changes were not significant. The proportion of physician-assigned A1C targets within ADA-recommended ranges increased from 56% to 66% post-intervention (P<0.0001. Conclusion: Physicians treating T2D are aware of the 2012 ADA Position Statement and believe that it may influence treatment goals. While patient-specific A1C targets were not significantly impacted, physicians indicated that they would make targets more or less stringent for lower and higher risk patients, respectively, across their practice. Further research into optimizing physician education regarding individualized A1C targets is warranted. Keywords

  19. In Situ Denitrification and Biological Nitrogen Fixation Under Enhanced Atmospheric Reactive Nitrogen Deposition in UK Peatlands

    Science.gov (United States)

    Ullah, Sami; Saiz Val, Ernesto; Sgouridis, Fotis; Peichl, Matthias; Nilsson, Mats

    2017-04-01

    Dinitrogen (N2) and nitrous oxide (N2O) losses due to denitrification and biological N2 fixation (BNF) are the most uncertain components of the nitrogen (N) cycle in peatlands under enhanced atmospheric reactive nitrogen (Nr) deposition. This uncertainty hampers our ability to assess the contribution of denitrification to the removal of biologically fixed and/or atmospherically deposited Nr in peatlands. This uncertainty emanates from the difficulty in measuring in situ soil N2 and N2O production and consumption in peatlands. In situ denitrification and its contribution to total N2O flux was measured monthly between April 2013 and October 2014 in peatlands in two UK catchments. An adapted 15N-Gas Flux method1 with low level addition of 15N tracer (0.03 ± 0.005 kg 15N ha-1) was used to measure denitrification and its contribution to net N2O production (DN2O/TN2O). BNF was measured in situ through incubation of selected sphagnum species under 15N2 gas tracer. Denitrification2 varied temporally and averaged 8 kg N-N2 ha-1 y-1. The contribution of denitrification was about 48% to total N2O flux3 of 0.05 kg N ha-1 y-1. Soil moisture, temperature, ecosystem respiration, pH and mineral N content mainly regulated the flux of N2 and N2O. Preliminary results showed suppression of BNF, which was 1.8 to 7 times lower in peatland mosses exposed to ˜15 to 20 kg N ha-1 y-1 Nr deposition in the UK than in peatland mosses in northern Sweden with background Nr deposition. Overall, the contribution of denitrification to Nr removal in the selected peatlands was ˜50% of the annual Nr deposition rates, making these ecosystems vulnerable to chronic N saturation. These results point to a need for a more comprehensive annual BNF measurement to more accurately account for total Nr input into peatlands and its atmospheric loss due to denitrification. References Sgouridis F, Stott A & Ullah S, 2016. Application of the 15N-Gas Flux method for measuring in situ N2 and N2O fluxes due to

  20. Using n-alkane records to constrain carbon cycle - hydrological cycle coupling: Case study from the Northern Hemisphere mid-latitudes during the PETM

    Science.gov (United States)

    Krishnan, S.; Pagani, M.; Tipple, B. J.

    2010-12-01

    The early Eocene was a warmer world compared to the present and is characterized by rising temperatures interspersed with rapid hyperthermal events. During the largest of these rapid warming events; the Paleocene-Eocene Thermal Maximum (PETM), proxy records suggest that sea surface temperatures (SST) rose by 3-5 deg. C in the tropics (Zachos et al., 2003, Tripati and Elderfield, 2004), >5 deg. C in the Arctic (Sluijs et al., 2006) and perhaps has high as 9 deg. C in some sub-Antarctic regions (Kennett and Stott, 1991; Thomas et al., 1999). This warming is believed to be the result of massive input of 13C-depleted carbon into the ocean-atmosphere system, evidenced by the large negative carbon isotope excursion (CIE) and carbonate dissolution associated with the event. However, there are several questions regarding the exact mechanism of warming and feedbacks between the carbon cycle and climate. Did climate shift prior to the main event that led to the release of isotopically light carbon? Do we observe consistent leads or lags between changes in carbon isotopes and hydrological conditions during warm intervals? This study aims to reconstruct hydrological changes in the in the Northern Hemisphere mid-latitudes during the PETM using terrestrial biomarkers. Terrestrial biomarkers, such leaf-wax lipids stored in sediments, have the unique advantage of recording carbon and hydrogen isotopic compositions of atmospheric CO2 (modified by plant fractionation) and precipitation (modified by plant fractionation and evapotranspiration), allowing evaluation of the relative timing of carbon and hydrogen isotopic (i.e., climate) shifts. In this study, we compile and present three mid-latitude PETM records from the Northern Hemisphere, i.e. Alamedilla (Spain), Cicogna and Forada (Italy). The Cicogna and Forada sections are located in the Belluno basin (~12 km apart). Preliminary results do not indicate any significant pre-excursion hydrogen isotope changes at Cicogna, while at

  1. Drought impacts on vegetation dynamics in the Mediterranean based on remote sensing and multi-scale drought indices

    Science.gov (United States)

    Trigo, Ricardo; Gouveia, Celia M.; Beguería, Santiago; Vicente-Serrano, Sergio

    2015-04-01

    Sciences, 12, 3123-3137, 2012. Trigo R.M., Añel J., Barriopedro D., García-Herrera R., Gimeno L., Nieto R., Castillo R., Allen M.R., Massey N. (2013), The record Winter drought of 2011-12 in the Iberian Peninsula [in "Explaining Extreme Events of 2012 from a Climate Perspective". [Peterson, T. C., M. P. Hoerling, P.A. Stott and S. Herring, Eds.] Bulletin of the American Meteorological Society, 94 (9), S41-S45. Vicente-Serrano S.M., López-Moreno J.I., Beguería S., Lorenzo-Lacruz J., Sanchez-Lorenzo A., García-Ruiz J.M., Azorin-Molina C., Móran-Tejeda E., Revuelto J., Trigo R., Coelho F., Espejo F.: Evidence of increasing drought severity caused by temperature rise in southern Europe. Environmental Research Letters, 9, 044001, 2014. Acknowledgements: This work was partially supported by national funds through FCT (Fundação para a Ciência e a Tecnologia, Portugal) under project QSECA (PTDC/AAGGLO/4155/2012).

  2. A New Tool for Nutrition App Quality Evaluation (AQEL): Development, Validation, and Reliability Testing.

    Science.gov (United States)

    DiFilippo, Kristen Nicole; Huang, Wenhao; Chapman-Novakofski, Karen M

    2017-10-27

    significant change over time (P>.05) for all but skill development (P=.001). Construct reliability was good for items assessing age appropriateness of apps for children, teens, and a general audience. In addition, construct reliability was acceptable for assessing app appropriateness for various target audiences (Cronbach alpha >.70). For the 5 main factors, ICC (1,k) was >.80, with a P value of app, ICC (2,15) was .98, with a P value of apps' qualities for clinical interventions by nutrition clinicians, educators, and researchers. Further efforts in validating AQEL in various contexts are needed. ©Kristen Nicole DiFilippo, Wenhao Huang, Karen M. Chapman-Novakofski. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 27.10.2017.

  3. Molecular diagnosis of microbial copathogens with influenza A(H1N1pdm09 in Oaxaca, Mexico

    Directory of Open Access Journals (Sweden)

    Ramírez-Palacios LR

    2018-04-01

    Full Text Available Luis Román Ramírez-Palacios,1 Diana Reséndez-Pérez,2 Maria Cristina Rodríguez-Padilla,2 Santiago Saavedra-Alonso,2 Olga Real-Najarro,3 Nadia A Fernández-Santos,4 Mario A Rodriguez Perez4 1Laboratorio Estatal de Salud Pública de Oaxaca, Oaxaca, 2Departamento de Inmunología y Virología, Facultad de Ciencias Biológicas, Universidad Autónoma de Nuevo León, San Nicolás de los Garza, Mexico; 3Consejería de Educación, Madrid, Spain; 4Instituto Politécnico Nacional (IPN, Centro de Biotecnología Genómica, Reynosa, Mexico Background: Multiple factors have been associated with the severity of infection by influenza A(H1N1pdm09. These include H1N1 cases with proven coinfections showing clinical association with bacterial contagions. Purpose: The objective was to identify H1N1 and copathogens in the Oaxaca (Mexico population. A cross-sectional survey was conducted from 2009 to 2012. A total of 88 study patients with confirmed H1N1 by quantitative RT-PCR were recruited. Methods: Total nucleic acid from clinical samples of study patients was analyzed using a TessArray RPM-Flu microarray assay to identify other respiratory pathogens. Results: High prevalence of copathogens (77.3%; 68 patients harbored one to three pathogens, predominantly from Streptococcus, Haemophilus, Neisseria, and Pseudomonas, were detected. Three patients (3.4% had four or five respiratory copathogens, whereas others (19.3% had no copathogens. Copathogenic occurrence with Staphylococcus aureus was 5.7%, Coxsackie virus 2.3%, Moraxella catarrhalis 1.1%, Klebsiella pneumoniae 1.1%, and parainfluenza virus 3 1.1%. The number of patients with copathogens was four times higher to those with H1N1 alone (80.68% and 19.32%, respectively. Four individuals (4.5%; two males, one female, and one infant who died due to H1N1 were observed to have harbored such copathogens as Streptococcus, Staphylococcus, Haemophilus, and Neisseria. Conclusion: In summary, copathogens were found in a

  4. Assessing the Equivalence of Paper, Mobile Phone, and Tablet Survey Responses at a Community Mental Health Center Using Equivalent Halves of a 'Gold-Standard' Depression Item Bank.

    Science.gov (United States)

    Brodey, Benjamin B; Gonzalez, Nicole L; Elkin, Kathryn Ann; Sasiela, W Jordan; Brodey, Inger S

    2017-09-06

    halves, with the potential to simplify future experimental methodologies. Among community mental health care recipients, the PROMIS items function similarly whether administered via paper, tablet, or mobile phone. User satisfaction across modalities was also similar. Because paper, tablet, and mobile phone administrations yielded similar results, the choice of technology should be based on factors such as convenience and can even be changed during a study without adversely affecting the comparability of results. ©Benjamin B Brodey, Nicole L Gonzalez, Kathryn Ann Elkin, W Jordan Sasiela, Inger S Brodey. Originally published in JMIR Mental Health (http://mental.jmir.org), 06.09.2017.

  5. The emotional and physical impact of wet age-related macular degeneration: findings from the wAMD Patient and Caregiver Survey

    Directory of Open Access Journals (Sweden)

    Varano M

    2016-02-01

    Full Text Available Monica Varano,1 Nicole Eter,2 Steve Winyard,3 Kim U Wittrup-Jensen,4 Rafael Navarro,5 Julie Heraghty6 On behalf of the wAMD Patient and Caregiver Survey Committee members 1Department of Ophthalmology, Fondazione GB Bietti-IRCCS, Rome, Italy; 2Department of Ophthalmology, University of Münster, Münster, Germany; 3Department of Policy and Campaigns, Royal National Institute of Blind People, London, UK; 4Bayer Pharma AG, Berlin, Germany; 5Instituto de Microcirugia Ocular, Barcelona, Spain; 6Macular Disease Foundation Australia, Sydney, NSW, Australia Objectives: This was a cross-sectional survey to evaluate the physical and emotional impact of wet age-related macular degeneration (wAMD on a global cohort of patients who were receiving (or had previously received antivascular endothelial growth factor injections, and caregivers (paid and unpaid.Methods: The survey was performed in nine countries using an ophthalmologist-devised questionnaire.Results: A total of 910 patients and 890 caregivers completed the questionnaire. Most patients had been diagnosed and receiving antivascular endothelial growth factor injections for more than 1 year (74.7% and 63.8%, respectively, and many patients (82.1% received support from a caregiver (usually a child/grandchild [47.3%] or partner [23.3%]. wAMD had a negative impact on most patients (71.6%; many rated fear (44.9%, sadness (39.9%, frustration (37.3%, and depression (34.0% as common. It was linked to physical consequences, such as difficulty in reading (61.1%. Many effects were significantly greater in patients with a longer duration of disease or with wAMD in both eyes. Some caregivers (unpaid also reported that caregiving had a negative impact on them (31.1%; many reported emotions such as sadness (34.9% and depression (24.4%, but many also felt useful (48.4%. Overall, 27.2% of caregivers (unpaid rated caregiving as inconvenient; this was linked to days of employment/personal obligations missed

  6. Evaluation of Technology-Enhanced Learning Programs for Health Care Professionals: Systematic Review.

    Science.gov (United States)

    Nicoll, Pam; MacRury, Sandra; van Woerden, Hugo C; Smyth, Keith

    2018-04-11

    satisfaction surveys, were found to be the most common types of TEL evaluations evident in the literature. The studies reviewed had low scores across reporting on ethical matters, design, and data collection categories. There continues to be a need to develop effective and standard TEL evaluation tools, and good quality studies that describe effective evaluation of TEL education for health care professionals. Studies often fail to provide sufficient detail to support transferability or direct future TEL health care education programs. ©Pam Nicoll, Sandra MacRury, Hugo C van Woerden, Keith Smyth. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 11.04.2018.

  7. The complex of PAMAM-OH dendrimer with Angiotensin (1–7 prevented the disuse-induced skeletal muscle atrophy in mice

    Directory of Open Access Journals (Sweden)

    Márquez-Miranda V

    2017-03-01

    Full Text Available Valeria Márquez-Miranda,1,2,* Johanna Abrigo,3,4,* Juan Carlos Rivera,3,4 Ingrid Araya-Durán,1 Javier Aravena,3,4 Felipe Simon,3,4 Nicolás Pacheco,1 Fernando Danilo González-Nilo,1,2,5 Claudio Cabello-Verrugio3,4 1Center for Bioinformatics and Integrative Biology (CBIB, Facultad de Ciencias Biologicas, Universidad Andres Bello, Santiago, 2Fundación Fraunhofer Chile Research, Las Condes, 3Departamento de Ciencias Biologicas, Facultad de Ciencias Biologicas & Facultad de Medicina, Universidad Andres Bello, 4Millennium Institute on Immunology and Immunotherapy, Santiago, 5Centro Interdisciplinario de Neurociencia de Valparaíso, Facultad de Ciencias, Universidad de Valparaíso, Valparaíso, Chile *These authors contributed equally to this work Abstract: Angiotensin (1–7 (Ang-(1–7 is a bioactive heptapeptide with a short half-life and has beneficial effects in several tissues – among them, skeletal muscle – by preventing muscle atrophy. Dendrimers are promising vehicles for the protection and transport of numerous bioactive molecules. This work explored the use of a neutral, non-cytotoxic hydroxyl-terminated poly(amidoamine (PAMAM-OH dendrimer as an Ang-(1–7 carrier. Bioinformatics analysis showed that the Ang-(1–7-binding capacity of the dendrimer presented a 2:1 molar ratio. Molecular dynamics simulation analysis revealed the capacity of neutral PAMAM-OH to protect Ang-(1–7 and form stable complexes. The peptide coverage ability of the dendrimer was between ~50% and 65%. Furthermore, an electrophoretic mobility shift assay demonstrated that neutral PAMAM-OH effectively bonded peptides. Experimental results showed that the Ang-(1–7/PAMAM-OH complex, but not Ang-(1–7 alone, had an anti-atrophic effect when administered intraperitoneally, as evaluated by muscle strength, fiber diameter, myofibrillar protein levels, and atrogin-1 and MuRF-1 expressions. The results of the Ang-(1–7/PAMAM-OH complex being intraperitoneally

  8. Development of a Web-Based Intervention for Addressing Distress in Caregivers of Patients Receiving Stem Cell Transplants: Formative Evaluation With Qualitative Interviews and Focus Groups

    Science.gov (United States)

    Pensak, Nicole Amoyal; Joshi, Tanisha; Simoneau, Teresa; Kilbourn, Kristin; Carr, Alaina; Kutner, Jean; Laudenslager, Mark L

    2017-06-22

    Mind Body Connection, How Thoughts Can Lead to Stress, Coping with Stress, Strategies for Maintaining Energy and Stamina, Coping with Uncertainty, Managing Changing Relationships and Communicating Needs, Getting the Support You Need, and Improving Intimacy) delivered via video instruction through a mobilized website. Feedback from stakeholder groups, focus groups, and individual interviews provided valuable feedback in key areas that was integrated into the development of Pep-Pal with the goal of enhancing dissemination, engagement, acceptability, and usability. ©Nicole Amoyal Pensak, Tanisha Joshi, Teresa Simoneau, Kristin Kilbourn, Alaina Carr, Jean Kutner, Mark L. Laudenslager. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 22.06.2017.

  9. Engaging a Community for Rare Genetic Disease: Best Practices and Education From Individual Crowdfunding Campaigns.

    Science.gov (United States)

    Ortiz, Romina Alicia; Witte, Steven; Gouw, Arvin; Sanfilippo, Ana; Tsai, Richard; Fumagalli, Danielle; Yu, Christine; Lant, Karla; Lipitz, Nicole; Shepphird, Jennifer; Alvina, Fidelia B; Cheng-Ho Lin, Jimmy

    2018-02-05

    with a higher success rate. Amplify Hope donors were more likely to support projects that were near their fundraising goals, and they found video far more effective for learning about genomics than any other medium. ©Romina Alicia Ortiz, Steven Witte, Arvin Gouw, Ana Sanfilippo, Richard Tsai, Danielle Fumagalli, Christine Yu, Karla Lant, Nicole Lipintz, Jennifer Shepphird, Fidelia B Alvina, Jimmy Cheng-Ho Lin. Originally published in the Interactive Journal of Medical Research (http://www.i-jmr.org/), 05.02.2018.

  10. Drought impacts on cereal yields in Iberia

    Science.gov (United States)

    Gouveia, Célia; Liberato, Margarida L. R.; Russo, Ana; Montero, Irene

    2014-05-01

    Spain in both considered drought events, however slightly less severe for 2012 than for 2005. In conclusion, and from an operational point of view, our results reveal the ability of the developed methodology to monitor droughts' impacts on crops productions and yields in Iberia. Acknowledgments: This work was partially supported by national funds through FCT (Fundação para a Ciência e a Tecnologia, Portugal) under project QSECA (PTDC/AAG-GLO/4155/2012) Garcia-Herrera R., Paredes D., Trigo R. M., Trigo I. F., Hernandez E., Barriopedro D. and Mendes M. A., 2007: The Outstanding 2004/05 Drought in the Iberian Peninsula: Associated Atmospheric Circulation, J. Hydrometeorol., 8, 483-498. Vicente-Serrano, Sergio M., Santiago Beguería, Juan I. López-Moreno, 2010: A Multiscalar Drought Index Sensitive to Global Warming: The Standardized Precipitation Evapotranspiration Index. J. Climate, 23, 1696-1718. Trigo R.M., Añel J., Barriopedro D., García-Herrera R., Gimeno L., Nieto R., Castillo R., Allen M.R., Massey N. (2013), The record Winter drought of 2011-12 in the Iberian Peninsula [in "Explaining Extreme Events of 2012 from a Climate Perspective". [Peterson, T. C., M. P. Hoerling, P.A. Stott and S. Herring, Eds.] Bulletin of the American Meteorological Society, 94 (9), S41-S45.

  11. Promoting ADL independence in vulnerable, community-dwelling older adults: a pilot RCT comparing 3-Step Workout for Life versus resistance exercise

    Directory of Open Access Journals (Sweden)

    Liu C

    2017-07-01

    Full Text Available Chiung-ju Liu,1,2 Huiping Xu,3,4 NiCole R Keith,2,4,5 Daniel O Clark2,4,6 1Department of Occupational Therapy, Indiana University School of Health and Rehabilitation Sciences, 2Indiana University Center for Aging Research, 3Department of Biostatistics, Indiana University Richard M. Fairbanks School of Public Health, 4Regenstrief Institute, Inc., 5Department of Kinesiology, Indiana University School of Physical Education and Tourism Management, 6Indiana University School of Medicine, Indianapolis, IN, USA Background: Resistance exercise is effective to increase muscle strength for older adults; however, its effect on the outcome of activities of daily living is often limited. The purpose of this study was to examine whether 3-Step Workout for Life (which combines resistance exercise, functional exercise, and activities of daily living exercise would be more beneficial than resistance exercise alone. Methods: A single-blind randomized controlled trial was conducted. Fifty-two inactive, community-dwelling older adults (mean age =73 years with muscle weakness and difficulty in activities of daily living were randomized to receive 3-Step Workout for Life or resistance exercise only. Participants in the 3-Step Workout for Life Group performed functional movements and selected activities of daily living at home in addition to resistance exercise. Participants in the Resistance Exercise Only Group performed resistance exercise only. Both groups were comparable in exercise intensity (moderate, duration (50–60 minutes each time for 10 weeks, and frequency (three times a week. Assessment of Motor and Process Skills, a standard performance test on activities of daily living, was administered at baseline, postintervention, and 6 months after intervention completion.Results: At postintervention, the 3-Step Workout for Life Group showed improvement on the outcome measure (mean change from baseline =0.29, P=0.02, but the improvement was not greater than

  12. La profecía de Freud: del psicoanálisis a la biología de la mente en el estudio del origen y tratamiento de la enfermedad mental

    Directory of Open Access Journals (Sweden)

    José Luis Jiménez-López

    2016-01-01

    Full Text Available Sigmund Freud fue considerado un científico revolucionario de la talla de Nicolás Copérnico y Charles Darwin por sus teorías psicológicas sobre el funcionamiento mental en un momento en el que la biología no podía explicarlo. En sus inicios, el psicoanálisis no fue aceptado por los profesionales de la medicina debido a la falta de verificación empírica de sus conclusiones y a la imposibilidad para identificar los sustratos orgánicos que Freud suponía que participaban en la psicopatología; sin embargo, a mediados del siglo pasado se convirtió en el principal fundamento para la psiquiatría en el tratamiento de la enfermedad mental, lo que la distanció del resto de las especialidades médicas. El psicoanálisis, como herramienta terapéutica, empezó a ser sustituido por tratamientos con evidencia empírica en el ámbito psiquiátrico como consecuencia de los descubrimientos sobre el mecanismo de acción de los psicofármacos y la aparición de psicoterapias breves. En este artículo se presenta un breve recorrido sobre el estudio de la enfermedad mental desde el nacimiento de la psiquiatría hasta la época actual, y los recientes hallazgos de las neurociencias que sugieren que se han empezado a descubrir los mecanismos orgánicos que Freud suponía involucrados en la génesis y tratamiento de los trastornos mentales. Abstract Sigmund Freud was considered a revolutionary scientist, as important as Nicolaus Copernicus and Charles Darwin, due to his psychological theories on mind’s operation at a moment when biology could not explain it. At the beginning, psychoanalysis was not accepted by medical professionals, since it was impossible to identify the organic substrata alleged by Freud to take part in psychopathology. Nevertheless, by the mid-20th century, psychoanalysis had become the main foundation of psychiatry, which distanced it from the rest of medical specializations. Biology of mind started substituting psychoanalysis in

  13. Influence of environmental factors on food intake among nursing home residents: a survey combined with a video approach

    Directory of Open Access Journals (Sweden)

    Buckinx F

    2017-07-01

    Full Text Available Fanny Buckinx,1 Jean-Yves Reginster,1 Alison Morelle,2 Nicolas Paquot,3 Nicole Labeye,3 Médéa Locquet,1 Stéphane Adam,4,* Olivier Bruyère1,5,* 1Department of Public Health, Epidemiology and Health Economics, University of Liège, 2Nutrition and Dietetics, Haute Ecole de la Province de Liège, 3Diabetes, Nutrition and Metabolic Diseases, University Teaching Hospital of Liège, 4Psychology of Senescence, 5Department of Sport Sciences and Rehabilitation, University of Liège, Liège, Belgium *These authors contributed equally to this work Background: In addition to the well-known physiological factors, dietary behavior that affects health seems to be influenced by a wide variety of environmental factors. The aim of this study was to assess, by means of an original video approach, the influence of the environment on food intake in nursing homes. Methods: The perception of the environment during meals in nursing homes was evaluated by residents and by two groups of volunteers who either work in the field of geriatrics, or who do not work in the field of geriatrics. First, a random sample of residents answered a self-administered questionnaire related to different indicators (ie, noise, space, comfort, light, odors, perceived satisfaction of meals, taste of meals, presentation of meals, service and setting. Second, two separate panels, one including the people who work in the field of geriatrics (ie, experts and one including the people who have no particular interest in geriatrics (ie, nonexperts, were asked to answer a questionnaire on their perception of the environment after having watched a video of the lunch in each nursing home. Then, the food intake of the residents was measured by a precise food-weighing method. Results: A total of 88 residents from nine different nursing homes, 18 experts and 45 nonexperts answered the questionnaires. This study highlighted that, on the one hand, after adjustment on confounding variables, the perception

  14. 3. forum bioenergy. Politics, market, finances, marketing and distribution, export. Proceedings 2007; 3. Forum Bioenergie. Politik, Markt, Finanzierung, Marketing and Vertrieb, Export. Tagungsband 2007

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    The following lectures were held (selection of topics): The decision to the thermal energy law and EEG from the cabinet meeting at 5th December, 2007 (Heiko Schwarzburger); Comment of the opposition to the cabinet decisions and outline of the political activities of the European policy (Heinz-Josef Fell); The meaning of new systems for utilization of land for soil protection and climatic change (Uwe Schneider); State of the art: laws and terms of references (Lothar Breidenbach); Bioenergy the interface industry - strategic challenges (Hilmar Platz); Actual developments with the promotion of the bioenergy by EEG and thermal energy law (Nicole Pippke); National biomass strategies in the European Union - project BAP DRIVER (Alexandra Lermen); Effects of the trade from biofuels to meet the development extensions of the European Union on area requirements (Enver Doruk Oezdemir); Energy region Rhein-Sieg: Renewable energies in the association - modelling of self-sufficient regions (Rolf Beyer); Potentials of value added in regions - results from the BMU project BioRegio (Georg Wagener Lohse); Posibilities and terms of references for increasing the potentials of biomass (Cornelia Behm); What can bioenergies perform in mix of renewable energies? - Discussion contribution for the limited potential of the bio energies (Susanne Jung); Panel discussion with representatives from the policy: Surface competition - full grain instead of full power; Fermentation gas - economy and experiences from bank view (Joerg-Uwe Fischer); Financing concept of large-scale projects by the example of the biological gas facility in Penkun (Balthasar Schramm); Economy factors for the gas feed - examples from consultant practice (Markus Helm); Stabilization or endangerment agriculture? Realizations from the field study 'biological gas facilities in Bavaria' (Wilfried Zoerner); Bioenergy - chances for investors (Daniel Kellermann); Private Equity within the range of bioenergy (Andrew Murphy

  15. Applications of direct-to-consumer hearing devices for adults with hearing loss: a review

    Directory of Open Access Journals (Sweden)

    Manchaiah V

    2017-05-01

    Full Text Available Vinaya Manchaiah,1–4 Brian Taylor,5 Ashley L Dockens,1 Nicole R Tran,1 Kayla Lane,1 Mariana Castle,1 Vibhu Grover1 1Department of Speech and Hearing Sciences, Lamar University, Beaumont, TX, USA; 2The Swedish Institute for Disability Research, Department of Behavioural Sciences and Learning, Linköping University, Linköping, Sweden; 3Audiology India, Mysore, 4Department of Speech and Hearing, School of Allied Health Sciences, Manipal University, Manipal, India; 5Taylor Audio LLC, Minneapolis, MN, USA Background: This systematic literature review is aimed at investigating applications of direct-to-consumer hearing devices for adults with hearing loss. This review discusses three categories of direct-to-consumer hearing devices: 1 personal sound amplification products (PSAPs, 2 direct-mail hearing aids, and 3 over-the-counter (OTC hearing aids.Method: A literature review was conducted using EBSCOhost and included the databases CINAHL, MEDLINE, and PsycINFO. After applying prior agreed inclusion and exclusion criteria, 13 reports were included in the review.Results: Included studies fell into three domains: 1 electroacoustic characteristics, 2 consumer surveys, and 3 outcome evaluations. Electroacoustic characteristics of these devices vary significantly with some meeting the stringent acoustic criteria used for hearing aids, while others producing dangerous output levels (ie, over 120-dB sound pressure level. Low-end (or low-cost devices were typically poor in acoustic quality and did not meet gain levels necessary for most adult and elderly hearing loss patterns (eg, presbycusis, especially in high frequencies. Despite direct-mail hearing aids and PSAPs being associated with lower satisfaction when compared to hearing aids purchased through hearing health care professionals, consumer surveys suggest that 5%–19% of people with hearing loss purchase hearing aids through direct-mail or online. Studies on outcome evaluation suggest positive

  16. A review on regional convection permitting climate modeling

    Science.gov (United States)

    van Lipzig, Nicole; Prein, Andreas; Brisson, Erwan; Van Weverberg, Kwinten; Demuzere, Matthias; Saeed, Sajjad; Stengel, Martin

    2016-04-01

    are addressed in future research. Coordinated modeling programs are crucially needed to advance parameterizations of unresolved physics and to assess the full potential of CPMs. Brisson, E., K. Van Weverberg, M. Demuzere, A. Devis, S. Saeed, M. Stengel, N.P.M. van Lipzig, 2016. How well can a convection-permitting climate model reproduce 1 decadal statistics of precipitation, temperature and cloud characteristics? Clim. Dyn. (minor revisions). Prein, Andreas F., Wolfgang Langhans, Giorgia Fosser, Andrew Ferrone, Nikolina Ban, Klaus Goergen, Michael Keller, Merja Tölle, Oliver Gutjahr, Frauke Feser, Erwan Brisson, Stefan Kollet, Juerg Schmidli, Nicole P. M. van Lipzig, Ruby Leung. (2015) A review on regional convection-permitting climate modeling: Demonstrations, prospects, and challenges. Reviews of Geophysics 53:10.1002/rog.v53.2, 323-361

  17. Book Reviews

    Directory of Open Access Journals (Sweden)

    Danker H. Schaareman

    1980-01-01

    . xvi + 329 pages. Maps, tables, plates, figures, index. - A. de Ruijter, S.F. Moore, Secular Ritual. Van Gorcum, Assen, 1977. 293 pp., B.G. Myerhoff (eds. - A. Ploeg, L.M. Serpenti, Cultivators in the swamps. Social structure and horticulture in a New Guinea society, Second edition. Van Gorcum, Assen, 1977, 308 pp., maps, tables, figures, glossary. - A. de Ruijter, R. Needham, Symbolic classifications. Goodyear Publishing Company Inc. Santa Monica, California. 1979. 78 pp. - Danker H. Schaareman, Urs Ramseyer, The art and culture of Bali. Oxford 1977: Oxford University Press. 265 pp., 405 pp., ill. - Anthony Shelton, E. Schwimmer, The Yearbook of Symbolic anthropology, London: C. Hurst and Co., 1978; pp. 230. - H. Steinhauer, M.A. Chlenov, Naselenie Molukkskix Ostrovov [The population of the Moluccas], Moscow 1976, 285 pp. - P. van de Velde, M.G. Leakey, The fossil hominids and an introduction to their context, 1968-1974, Oxford: Clarendon Press, 1978. Volume 1 of R.E. Leakey & G.Ll. Isaac (general editors: Koobi Fora - researches into geology, palaeontology, and human origins. 191 pages; 28 plates and numerous figures; tables; index., R.E. Leakey (eds. - Leontine E. Visser, P.A. Stott, Nature and man in South East Asia, 1978, S.O.A.S., London, 183 pp., fig., phot., subject index. - J.J. de Wolf, F. Bovenkerk, Toen en thans: De sociale wetenschappen in de jaren dertig en nu. Onder redactie van F. Bovenkerk, H.J.M. Claessen, B. van Heerikhuizen, A.J.F. Köbben, N. Wilterdink. 1978 Ambo, Baarn., H.J.M. Claessen, B. van Heerikhuizen (eds.

  18. Factors controlling carbon isotopic composition of land snail shells estimated from lab culturing experiment

    Science.gov (United States)

    Zhang, Naizhong; Yamada, Keita; Yoshida, Naohiro

    2014-05-01

    contribution of different carbon sources for each snail individual: to cabbage (C3 plant) fed groups, the contributions of diet, atmospheric CO2 and ingested limestone vary in a range of 66~80%, 16~24% and 0~13%, respectively. And to corn (C4 plant) fed groups, because of the possible food stress (lower consumption ability of C4 plant), they vary in 56~64%, 18~20% and 16~26%, respectively. We will discuss how these results could be consistent to the observations, which suggests our calculations are suitable and believable. In addition, we will discuss the carbon isotope fractionation during egg laying and hatching of land snails, too. [1] Goodfriend, 1992, Quaternary Sciences Reviews. 11, 665-685 [2] Yanes et al. 2009. Geochimica et Cosmochimica Acta, 73, 4077-4099 [3] Yanes et al., 2013. Palaeogeography, Plaeoclimatology, Palaeoecology, 378, 91-102 [4] Goodfriend and Hood, 1983. Radiocarbon, 25, 810-830 [5] Goodfriend and Stipp, 1983. Geology, 11, 575-577 [6] Stott, 2002. Earth and Planetary Science Letters, 195, 249-259 [7] Metref et al., 2003. Earth and Planetary Science Letters, 211, 381-393 [8] Romaniello et al., 2008. Quaternary Geochronology, 3, 68-75

  19. Drought trends in the Iberian Peninsula over the last 112 years

    Science.gov (United States)

    Gouveia, Célia M.; Ramos, Patrícia; Russo, Ana; Trigo, Ricardo M.

    2015-04-01

    time between drought events, although no clear pattern has emerged. Gouveia C.M., Bastos A., Trigo R.M., DaCamara C.C. (2012) "Drought impacts on vegetation in the pre and post-fire events over Iberian Peninsula". Natural Hazards and Earth System Sciences, 12, 3123-3137, 2012. Hoerling, M., Eischeid, J., Perlwitz, J., Quan, X., Zhang, T., and Pegion, P. (2012). On the increased frequency of Mediterranean drought. J. Clim., 25, 2146-2161. Trigo R.M., Añel J., Barriopedro D., García-Herrera R., Gimeno L., Nieto R., Castillo R., Allen M.R., Massey N. (2013), The record Winter drought of 2011-12 in the Iberian Peninsula [in "Explaining Extreme Events of 2012 from a Climate Perspective". [Peterson, T. C., M. P. Hoerling, P.A. Stott and S. Herring, Eds.] Bulletin of the American Meteorological Society, 94 (9), S41-S45. Vicente-Serrano S.M., López-Moreno J.I., Beguería S., Lorenzo-Lacruz J., Sanchez-Lorenzo A., García-Ruiz J.M., Azorin-Molina C., Móran-Tejeda E., Revuelto J., Trigo R., Coelho F., Espejo F.: Evidence of increasing drought severity caused by temperature rise in southern Europe. Environmental Research Letters, 9, 044001, 2014. Acknowledgements: This work was partially supported by national funds through FCT (Fundação para a Ciência e a Tecnologia, Portugal) under project QSECA (PTDC/AAGGLO/4155/2012).

  20. Compression stockings significantly improve hemodynamic performance in post-thrombotic syndrome irrespective of class or length.

    Science.gov (United States)

    Lattimer, Christopher R; Azzam, Mustapha; Kalodiki, Evi; Makris, Gregory C; Geroulakos, George

    2013-07-01

    Graduated elastic compression (GEC) stockings have been demonstrated to reduce the morbidity associated with post-thrombotic syndrome. The ideal length or compression strength required to achieve this is speculative and related to physician preference and patient compliance. The aim of this study was to evaluate the hemodynamic performance of four different stockings and determine the patient's preference. Thirty-four consecutive patients (40 legs, 34 male) with post-thrombotic syndrome were tested with four different stockings (Mediven plus open toe, Bayreuth, Germany) of their size in random order: class 1 (18-21 mm Hg) and class II (23-32 mm Hg), below-knee (BK) and above-knee thigh-length (AK). The median age, Venous Clinical Severity Score, Venous Segmental Disease Score, and Villalta scale were 62 years (range, 31-81 years), 8 (range, 1-21), 5 (range, 2-10), and 10 (range, 2-22), respectively. The C of C0-6EsAs,d,pPr,o was C0 = 2, C2 = 1, C3 = 3, C4a = 12, C4b = 7, C5 = 12, C6 = 3. Obstruction and reflux was observed on duplex in 47.5% legs, with deep venous reflux alone in 45%. Air plethysmography was used to measure the venous filling index (VFI), venous volume, and time to fill 90% of the venous volume. Direct pressure measurements were obtained while lying and standing using the PicoPress device (Microlab Elettronica, Nicolò, Italy). The pressure sensor was placed underneath the test stocking 5 cm above and 2 cm posterior to the medial malleolus. At the end of the study session, patients stated their preferred stocking based on comfort. The VFI, venous volume, and time to fill 90% of the venous volume improved significantly with all types of stocking versus no compression. In class I, the VFI (mL/s) improved from a median of 4.9 (range, 1.7-16.3) without compression to 3.7 (range, 0-14) BK (24.5%) and 3.6 (range, 0.6-14.5) AK (26.5%). With class II, the corresponding improvement was to 4.0 (range, 0.3-16.2) BK (18.8%) and 3.7 (range, 0.5-14.2) AK (24

  1. Carboxyl-modified single-wall carbon nanotubes improve bone tissue formation in vitro and repair in an in vivo rat model

    Directory of Open Access Journals (Sweden)

    Barrientos-Durán A

    2014-09-01

    Full Text Available Antonio Barrientos-Durán,1,5,* Ellen M Carpenter,2 Nicole I zur Nieden,3 Theodore I Malinin,4 Juan Carlos Rodríguez-Manzaneque,5 Laura P Zanello1,* 1Department of Biochemistry, University of California Riverside, Riverside, CA, USA; 2Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, South Los Angeles, CA, USA; 3Department of Cell Biology and Neuroscience, Stem Cell Center, College of Natural and Agricultural Sciences, University of California Riverside, Riverside, CA, USA; 4Tissue Bank, Department of Orthopedics, University of Miami Miller School of Medicine, Miami, FL, USA; 5Pfizer-University of Granada-Junta de Andalucía Centre for Genomics and Oncological Research (GENYO, Granada, Spain *These authors contributed equally to this workAbstract: The clinical management of bone defects caused by trauma or nonunion fractures remains a challenge in orthopedic practice due to the poor integration and biocompatibility properties of the scaffold or implant material. In the current work, the osteogenic properties of carboxyl-modified single-walled carbon nanotubes (COOH–SWCNTs were investigated in vivo and in vitro. When human preosteoblasts and murine embryonic stem cells were cultured on coverslips sprayed with COOH–SWCNTs, accelerated osteogenic differentiation was manifested by increased expression of classical bone marker genes and an increase in the secretion of osteocalcin, in addition to prior mineralization of the extracellular matrix. These results predicated COOH–SWCNTs’ use to further promote osteogenic differentiation in vivo. In contrast, both cell lines had difficulties adhering to multi-walled carbon nanotube-based scaffolds, as shown by scanning electron microscopy. While a suspension of SWCNTs caused cytotoxicity in both cell lines at levels >20 µg/mL, these levels were never achieved by release from sprayed SWCNTs, warranting the approach taken. In vivo, human allografts formed by the

  2. 从查韦斯到马杜罗的委内瑞拉外交政策--兼具延续性和现实政治变化的特点%The Venezuelan foreign policy from Chávez to Maduro---Between Continuity and Change Realpolitik

    Institute of Scientific and Technical Information of China (English)

    罗伯特·曼西亚·布兰科[西](著); 蓝博(译)

    2015-01-01

    The transition between President Hugo Chávez,who deceased in March 2013,and this designated successor, President Nicolás Maduro,doesn't broadly defines the articulation of a new foreign policy strategy for the Bolivarian Re-public of Venezuela.Caracas still support the configuration of a multipolar and multilateral no hegemonic world,perspec-tive which continues to maintain a tense struggle with the US despite the timid attempts to rearrange the bilateral relation-ship.However,while priority in efforts to strengthen the Venezuelan hemispheric position through regional integration, particularly within the CELAC and MERCOSUR,some paralysis have been observed of action around ALBA,key root of Chávez's external action.In contrast,Maduro begins to design a strategic partnership with China that is sensed as a prior-ity in the short and medium term,particularly relevant to the currently existing financial and economic crisis in Venezuela.%2013年3月乌戈·查韦斯去世,政权交到了他生前指定的接班人尼古拉斯·马杜罗手中。从总体上看,委内瑞拉玻利瓦尔共和国新政府的对外政策没有重大调整,委内瑞拉政府将继续致力于建立多极化、多边主义和反对霸权主义的世界格局。委内瑞拉正尝试改善与美国的双边关系,但是未来的两国关系依然会非常紧张。同时,马杜罗政府重视通过区域一体化来提升委内瑞拉在西半球的地位,特别是在拉美和加勒比国家共同体(CELAC)及南方共同市场(MERCOSUR)中的地位。值得注意的是,马杜罗政府暂停了美洲玻利瓦尔联盟(ALBA)的援助活动,这原本是查韦斯的外交核心。另外,在应对国内严重的政治和经济危机的同时,马杜罗开始计划和中国建立战略伙伴关系,这将是未来很长一段时间马杜罗政府的外交重心。

  3. Annotation an effective device for student feedback: a critical review of the literature.

    Science.gov (United States)

    Ball, Elaine C

    2010-05-01

    of annotation influences student learning and assessment or, indeed, helps tutors to employ better annotative practices [Juwah, C., Macfarlane-Dick, D., Matthew, B., Nicol, D., Ross, D., Smith, B., 2004. Enhancing student learning through effective formative feedback. The Higher Education Academy, 1-40; Jewitt, C., Kress, G., 2005. English in classrooms: only write down what you need to know: annotation for what? English in Education, 39(1), 5-18]. There is little evidence on ways to heighten students' self-awareness when their essays are returned with annotated feedback [Storch, N., Tapper, J., 1997. Student annotations: what NNS and NS university students say about their own writing. Journal of Second Language Writing, 6(3), 245-265]. The literature review clarifies forms of annotation as feedback practice and offers a summary of the challenges and usefulness of annotation. Copyright 2009. Published by Elsevier Ltd.

  4. Intervención docente y aprendizaje en asignaturas fundamentales de la Enfermería Teaching intervention and learning in fundamental subjects of Nursing

    Directory of Open Access Journals (Sweden)

    Ma. Martha Marín Laredo

    2008-08-01

    Full Text Available El presente trabajo surge de la inquietud basada en la experiencia en el campo laboral del sector salud y, sobre todo, en la adquirida en el ámbito educativo, donde se detectaron debilidades en la relación intervención docente y aprendizaje, de docentes y alumnos, en procedimientos de enfermería -asistenciales y preventivos- en la carrera de Licenciatura en Enfermería en la Universidad Michoacana de San Nicolás de Hidalgo (UMSNH, México. Lo anterior se ha observado especialmente en el 1º y 2º nivel de atención, en las instituciones de salud, donde los estudiantes tienen que aplicar las competencias adquiridas durante su formación. Por tal motivo surgió la necesidad de evaluar el proceso de aprendizaje de los estudiantes de las asignaturas Elementos Básicos de Enfermería y Enfermería en Salud Pública, que se cursan en el 2º. Semestre de la carrera y que son fundamentales en la formación de las (o enfermeras (o. De esta manera se evaluó el carácter que adquiere la intervención docente durante el proceso de aprendizaje de los alumnos de enfermería. Los resultados cuantitativos y cualitativos se constituyen en elementos de reflexión y análisis para incidir en cambios en la intervención docente, pues es un reflejo sistematizado de lo que ocurre en el proceso de formación de la carrera de enfermería.The present work arises from the worry based on the experience in the labor field of the sector health and, mainly, in the one acquired in the educational environment, where weaknesses were detected in the educational intervention and learning relationship, of teachers and students, in Nursery procedures - assistance and preventive - in the career of Degree in Nursery in the Michoacan University of San Nicolas of Hidalgo (MUSNH, Mexico. The above-mentioned has been observed especially in the 1º and 2º level of attention, in the institutions of health, where the students have to apply the acquired skills during their formations

  5. Transcultural and Transcorporal Neighbors: Japanese Performance Utopias in Jerzy Grotowski, Eugenio Barba and Phillip B. Zarrilli

    Directory of Open Access Journals (Sweden)

    Leo Rafolt

    2015-12-01

    Full Text Available Transcultural and Transcorporal Neighbors: Japanese Performance Utopias in  Jerzy Grotowski, Eugenio Barba and Phillip B. Zarrilli This paper is mainly focused on the concept of transcultural bodily knowledge elaborated by Eugenio Barba and Nicola Savarese in their concept of theatre anthropology. Their research on pre-existent and pre-expressive values of the human movement, especially considering Asian theatre and performative practices, will be reexamined in the context of over-imposed interculturalism in Humanities and Social Studies. The focus will be thus put on the modifications of the bodily knowledge in this sense (Yuasa, as well as on the (reappropriations of the Asian philosophical/theoretical embodiment schemes in the Western thought, not only from the standpoint of performative research made by Eugenio Barba and Phillip B. Zarrilli, but also from the standpoint of Shusterman’s pragmatic reinterpretations of Merleau-Ponty’s legacy, Schechner/Turner’s anthropology of human performativity, etc. In this context, the key idea of unique transcultural background of the human kinesis, employed mainly by Barba, will be put in an overall context of contemporary (transcultural utopism. The key element for interpretation will thus be an overall context of Asian martial arts practice, especially the significance of ‘iemoto principle’ (hereditary bodily technique for the establishment of Grotowski’s, Barba’s and Zarrilli’s psychology and physiology of performance tactics.   Transkulturowi i transcieleśni sąsiedzi: japońskie utopie performatywne u Jerzego Grotowskiego, Eugenia Barby i Philipa B. Zarrilliego Artykuł skupia się głównie na pojęciu transkulturowej wiedzy cielesności, wypracowanym przez Eugenia Barbę i Nicolę Savaresego w ich ujęciu antropologii widowiska. Ich badania nad uprzednimi i przedekspresywnymi wartościami ruchu ludzkiego, zwłaszcza w kontekście teatru azjatyckiego i praktyk performatywnych

  6. Book reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2009-05-01

    Full Text Available Johnny Tjia; A grammar of Mualang: An Ibanic language of West Kalimantan, Indonesia (Alexander Adelaar Christopher Moseley (ed.; Encyclopedia of the world’s endangered languages (Peter K. Austin Ian Rae and Morgen Witzel; The Overseas Chinese of South east Asia: History, culture, business (Chin Yee Whah Ab Massier; The voice of the law in transition: Indonesian jurists and their languages, 1915-2000 (Dwi Noverini Djenar Henk Schulte Nordholt and Gerry van Klinken (eds; Renegotiating boundaries: Local politics in post-Suharto Indonesia (Maribeth Erb Nghia M. Vo; The Vietnamese boat people, 1954 and 1975-1992 (Martin Grossheim O.W. Wolters; Early Southeast Asia: Selected essays [edited by Craig J. Reynolds] (Hans Hägerdal Michael W. Scott; The severed snake: Matrilineages, making place, and a Melanesian Christianity in Southeast Solomon Islands (Menno Hekker John H. McGlynn, Oscar Motuloh, Suzanne Charlé, Jeffrey Hadler, Bambang Bujono, Margaret Glade Agusta, and Gedsiri Suhartono; Indonesia in the Soeharto years: Issues, incidents and images (David Henley Hanneke Hollander; Een man met een speurdersneus: Carel Groenevelt (1899-1973, beroepsverzamelaar voor Tropenmuseum en Wereldmuseum in Nieuw-Guinea (Anna-Karina Hermkens Balk, G.L., F. van Dijk and D.J. Kortlang (with contributions by F.S. Gaastra, Hendrik E. Niemeijer and P. Koenders; The Archives of the Dutch East India Company (VOC and the local institutions in Batavia (Jakarta (Ton Kappelhof Gusti Asnan; Memikir ulang regionalisme: Sumatera Barat tahun 1950-an (Gerry van Klinken Lise Lavelle; Amerta Movement of Java 1986-1997: An Asian movement improvisation (Dick van der Meij Nicole-Claude Mathieu (ed.; Une maison sans fille est une maison morte: La personne et le genre en sociétés matrilinéaires et/ou uxorilocales (Joke van Reenen Henk Schulte Nordholt; Indonesië na Soeharto: Reformasi en restauratie (Elske Schouten V.I. Braginsky;

  7. Silencing of Foxp3 delays the growth of murine melanomas and modifies the tumor immunosuppressive environment

    Directory of Open Access Journals (Sweden)

    Franco-Molina MA

    2016-01-01

    Full Text Available Moisés A Franco-Molina,* Diana F Miranda-Hernández,* Edgar Mendoza-Gamboa, Pablo Zapata-Benavides, Erika E Coronado-Cerda, Crystel A Sierra-Rivera, Santiago Saavedra-Alonso, Reyes S Taméz-Guerra, Cristina Rodríguez-Padilla Immunology and Virology Department, Biological Sciences Faculty, University Autonoma of Nuevo León (UANL, San Nicolás de los Garza, Nuevo León, Mexico*These authors contributed equally to this work Abstract: Forkhead box p3 (Foxp3 expression was believed to be specific for T-regulatory cells but has recently been described in non-hematopoietic cells from different tissue origins and in tumor cells from both epithelial and non-epithelial tissues. The aim of this study was to elucidate the role of Foxp3 in murine melanoma. The B16F10 cell line Foxp3 silenced with small interference Foxp3 plasmid transfection was established and named B16F10.1. These cells had lower levels of Foxp3 mRNA (quantitative real-time reverse transcription-polymerase chain reaction [0.235-fold], protein (flow cytometry [0.02%], CD25+ expression (0.06%, cellular proliferation (trypan blue staining, and interleukin (IL-2 production (enzyme-linked immunosorbent assay [72.35 pg/mL] than those in B16F10 wild-type (WT cells (P<0.05. Subcutaneous inoculation of the B16F10.1 cell line into C57BL/6 mice delayed the time of visible tumor appearance, increased the time of survival, and affected the weight of tumors, and also decreased the production of IL-10, IL-2, and transforming growth factor beta compared with mice inoculated with the B16F10 WT cell line. The B16F10.1 cells derived from tumors and free of T-cells (isolated by Dynabeads and plastic attachment expressed relatively lower levels of Foxp3 and CD25+ than B16F10 WT cells (P<0.05 in a time-dependent manner. The population of tumor-infiltrating lymphocytes of T CD4+ cells (CD4+, CD4+CD25+, and CD4+CD25+Foxp3+ increased in a time-dependent manner (P<0.05 in tumors derived from B16F10 WT cells

  8. Pour paraître à la cour : les habits de Marie-Fortunée d’Este, princesse de Conti (1731-1803 

    Directory of Open Access Journals (Sweden)

    Aurélie Chatenet-Calyste

    2012-02-01

    Full Text Available Par son mariage en 1759 avec Louis-François-Joseph de Bourbon-Conti, Marie-Fortunée d’Este (1731-1803, fille du duc italien François III d’Este de Modène, devient princesse du sang en France. L’heureuse conservation de ses comptes permet d’étudier sa garde-robe et de réfléchir aux modalités du paraître vestimentaire à la cour de la fin du XVIIIe siècle. Tenir son rang à Versailles passe pour la princesse par des dépenses élevées, le port d’étoffes luxueuses et le choix de marchands réputés. Cette étude de cas invite au-delà à envisager la spécificité de l’apparence à la cour d’une princesse devenue en 1776 une épouse séparée au budget limité. Elle interroge également les contraintes physiques de l’habit de cour à la lumière des nouvelles valeurs de confort et de liberté, tout particulièrement pour une femme d’âge mûr et maladive qui ne paraît plus guère dans le monde aulique.To be received at court: the clothes of Mary Fortunate d'Este, Princess of Conti (1731-1803 - Aurélie Chatenet-Calyste is a French researcher and also teaches at the University of Champagne-Ardenne. After passing the French high-level competitive examination for recruitment of teachers in history (In French Agrégation, she has defended her thesis “A feminine and aristocratic consumption at the end of the 18th century : Marie-Fortunée d’Este, princesse de Conti” on November the 27 th at the University of Limoges. Her researches concern gender, consumption and court history. Her recent papers are « La femme, maîtresse de maison ? », Histoire, économie et société, 2009/4, p. 21-34 ; « Une princesse et son livret de comptes : Marie-Fortunée d’Este, princesse de Conti (1731-1803 », dans Entre mémoire et histoire : écriture ordinaire et émergence de l'individu, éd. par Nicole Lemaitre et Sylvie Mouysset (édition électronique, 134e Congrès national des sociétés historiques et scientifiques

  9. Evidence Based Research Activities, Interests and Opportunities Exist for Practitioners in all Library Sectors in the British Isles. A review of: McNicol, Sarah. “Is Research an Untapped Resource in the Library and Information Profession?” Journal of Librarianship and Information Science 36.3 (September 2004:119-26.

    Directory of Open Access Journals (Sweden)

    Julie McKenna

    2006-03-01

    Full Text Available Objective – To scope the range, nature and challenges of present, planned and future research by practitioners within libraries in the British Isles. Design – A series of survey questionnaires sent by mail. Setting – Public, academic, health, special and school libraries of the British Isles. Subjects – A total of 2384 questionnaires were sent out and 334 responses were received. 62 academic libraries, 83 health libraries, 78 public libraries, 63 school libraries and 48 special libraries participated in the study. Methods – This study was undertaken in 2003 by a research team at the University of Central England. Survey questionnaires were sent by mail to library directors in all public library authorities, academic libraries, health libraries and special libraries in England, Wales, Scotland, Northern Ireland and the Republic of Ireland. In addition, questionnaires were sent to the librarians in all state and independent schools within a sample of nine local education authorities. Each participant was asked to identify past and future research issues of interest and the barriers to research practice within their library. Research was defined to include work on both externally funded and inhouse projects and examples of the types of activities that this might include were provided. Main results – Half the respondents reported that they had been involved in some form of research in the past two years, with the lowest level of involvement from school libraries and the highest in public libraries. Generally, only the library directly involved in conducting the research made use of the findings and a gap in the dissemination of results was identified across sectors. User surveys were the most common form of research undertaken across libraries and slightly fewer respondents intended to carry out research in the coming twelve months than had in the past (the area most commonly mentioned was user surveys. Information and communications technology (ICT was an area of planned future research in all libraries, as were user needs and user behaviour. The most frequently cited barriers to research activity across all sectors were lack of time and financial resources. Staff skills and the lack of focus on practical problems to solve were indicated as a barrier in health, public and academic libraries. Libraries reported a range of common uses for the research findings including: informing strategic and service planning; providing benchmarking data and measuring the effectiveness of services; identification of marketing and public relations opportunities; discovery of staff training needs; and use of the results to demonstrate the value of libraries to funding bodies. Conclusion – This study provides insight into practitioner‐focused areas of research interest and possible areas for future investigation. As the author reports in her conclusion, the survey results cannot be considered representative of the wider population. Since research interests often overlap, a sector wide or cross‐sectoral research approach should be considered to allow library staff to identify and resolve common problems. Wide dissemination of research results within the practitioner community would be of benefit to all. Greater communication between practitioner and information science communities is also encouraged, as these communities’ work is mutually beneficial.

  10. Feasibility and Preliminary Effectiveness of the Homework Intervention Strategy (eHIS) Program to Enhance Male Condom Use: Research Protocol.

    Science.gov (United States)

    Glowacka, Marta; Yardley, Lucy; Stone, Nicole; Graham, Cynthia A

    2018-01-02

    types of condoms and lubricants on their own in a no-pressure situation. Following T1, participants are asked to complete the T2 and T3 measures at 4 and 10 weeks, respectively. Data collection for the study is completed. Data analysis is in progress and is expected to be completed by February 2018. This brief, home-based, self-guided program may lead to increased consistent and correct condom use. Online delivery can make the program an easily accessible and low-cost health promotion intervention, which has the potential to reach a wide and diverse audience. If results of the current study show the program's feasibility and preliminary effectiveness in changing condom use related outcomes, a larger scale randomized controlled trial (RCT) will be conducted. Research Registry: researchregistry2325; http://www.researchregistry.com/browse-the-registry.html# home/registrationdetails/58da6cad1d7ab0314337d076/ (Archived by WebCite at http://www.webcitation.org/6vXs6S9XW). ©Marta Glowacka, Lucy Yardley, Nicole Stone, Cynthia A Graham. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 02.01.2018.

  11. Aspectos Históricos y Sociales del Transplante Hepático

    Directory of Open Access Journals (Sweden)

    Enrique Moreno González

    1999-12-01

    Full Text Available

    Resultados en la Comunidad Económica Europea (Cee. Estado del Arte

    Hoy es un día muy especial por haberme permitido acercarme a esta insigne Corporación, y a pesar de mis escasos méritos, recibirme como Miembro Honorario de la misma.

    Me doy cuenta de que entro a la Academia Nacional de Medicina que fue establecida por la Ley 71 de 1890, gracias al deseo expreso de los doctores Jorge Holguín, Adriano Tribín, Enrique de Narváez y Miguel Angel Peñarredonda de transformar la Sociedad nacida en el año de 1873 para el estudio y adelanto de las ciencias médicas y naturales, solidarizar al cuerpo médico y darle unidad al ejercicio profesional. Me parece sentir las voces gentiles de augustos caballeros como Manuel Plata Azuero, catedrático de Terapéutica y hábil parlamentario; Nicolás Osorio, eximio investigador y Decano de la Universidad; Liborio Zerda, extraordinario naturalista, apóstol de la educación; Leoncio Barreto, catedrático, farmaceuta y obstetra de gran prestigio; Evaristo García, catedrático polifacético y profundo humanista; y el joven médico bugueño Abraham Aparicio, más tarde Concejal y Alcalde de esta maravillosa ciudad de Bogotá. Reciban y acepten con benevolencia este recuerdo que me embarga al entrar en esta sede, sintiendo con fuerza el honor que ustedes me hacen al introducirme en esta Academia.

    Acercarme hoy a Colombia es volver a disfrutar del paisaje andino, del recuerdo de las vasijas y botellas quimbaya, excelsos orfebres de la orilla del río Cauca; sorprenderme de nuevo con el inolvidable trabajo del oro de los chibchas o estremecerme frente a los monumentos y cámaras funerarias megalíticas de la cultura de San Agustín con sus enormes estatuas de piedra de tipo zoomorfo que, tanta fuerza expresiva poseen.

    España se introdujo en el arte colombiano, especialmente con el mudéjar que tan importantes ejemplos tiene aquí en el presbiterio de las Iglesias de

  12. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2008-12-01

    . Translated and annotated by Felicia Brichoux (Nicole Revel Joos van Vugt, José Eijt, Marjet Derks (eds; Tempo doeloe, tempo sekarang; Het proces van Indonesianisering in Nederlandse orden en congregaties (Karel Steenbrink Nancy Eberhardt; Imagining the course of life; Self-transformation in a Shan Buddhist community (Nicholas Tapp J.C. Smelik, C.M. Hogenstijn, W.J.M. Janssen; A.J. Duymaer van Twist; Gouverneur-Generaal van Nederlands-Indi? (1851-1856 (Gerard Termorshuizen David Steinberg; Turmoil in Burma; Contested legitimacies in Myanmar (Sean Turnell Carl A. Trocki; Singapore; Wealth, power and the culture of control (Bryan S. Turner Matthew Isaac Cohen; The Komedie Stamboel; Popular theatre in colonial Indonesia, 1891-1903 (Holger Warnk Jörgen Hellman; Ritual fasting on West Java (Robert Wessing Waruno Mahdi; Malay words and Malay things; Lexical souvenirs from an exotic archipelago in German publications before 1700 (Edwin Wieringa RECENT PUBLICATIONS Russell Jones, C.D. Grijns, J.W. de Vries, M. Siegers (eds; Loan-words in Indonesian and Malay VERHANDELINGEN 249 Peter Carey: The power of prophecy. Prince Dipanagara and the end of an old order in Java, 1785-1855

  13. PREFACE: 3rd International Workshop on Materials Analysis and Processing in Magnetic Fields (MAP3)

    Science.gov (United States)

    Sakka, Yoshio; Hirota, Noriyuki; Horii, Shigeru; Ando, Tsutomu

    2009-07-01

    the journal Science and Technology of Advanced Materials. All articles have been refereed by experts in the field. Both of these journals are fully accessible electronically and can be cited and referenced in the usual way. It is our hope that the reader will enjoy and profit from the MAP3 Proceedings. Hitoshi Wada (Kashiwa, Japan) Chair Eric Beaugon (Grenoble, France) Hans J Schneider-Muntau (Tallahassee, USA) Co-chair Advisory Board Shigeo Asai (Nagoya, Japan) Koichi Kitazawa (Tokyo, Japan) Mitsuhiro Motokawa (Sendai, Japan) Shoogo Ueno (Fukuoka, Japan) Robert Tournier (Grenoble, France) Justin Schwartz (Tallahassee, USA) J C Maan (Nijmegen, Netherland) Scientific Committee Yoshifumi Tanimoto (Hiroshima, Japan) Masuhiro Yamaguchi (Yokohama, Japan) Tsunehisa Kimura (Kyoto, Japan) Yoshio Sakka (Tsukuba Japan) Ryoichi Aogaki (Tokyo, Japan) Jyunji Miyakoshi (Hirosaki, Japan) Kazuo Watanabe (Sendai, Japan) James M Valles Jr. (Providence, USA) Joon Pyo Park (Pohang, Korea) Qiang Wang (Shenyang, China) Nicole Pamme (Hull, UK) Sophie Rivoirard (Grenoble, France) P C M Christianen (Nijmegen, Netherland) Local Organizing Committee Isao Yamamoto Masafumi Yamato Shigeru Horii Norihito Sogoshi Masateru Ikehata Noriyuki Hirota Tsutomu Ando Proceedings Editorial Board Yoshio Sakka Noriyuki Hirota Shigeru Horii Tsutomu Ando Conference photograph

  14. Diagnóstico ecológico para la conservación de Jatropha spp. (Euphorbiaceae y sus hábitats, en la Reserva Tehuacán-Cuicatlán, México

    Directory of Open Access Journals (Sweden)

    Nancy Hernández-Nicolás

    2015-03-01

    Full Text Available Jatropha spp., es un importante recurso fitogenético usado como alimento, medicina y biocombustible. En este estudio verificamos la identidad taxonómica de las especies de Jatropha para la Reserva de la Biosfera Tehuacán-Cuicatlán, y las unidades ambientales (UA que ocupan. Evaluamos el estado de conservación de sus hábitats y la vulnerabilidad de las poblaciones de Jatropha. Los sitios de muestreo seleccionados en la Reserva fueron 15. El trabajo taxonómico estuvo basado en especímenes, descripciones originales y material tipo de herbarios y aquellos en línea. Las UA fueron clasificadas mediante variables biofísicas y el software gvSIG. Los atributos ecológicos fueron determinados con análisis cuantitativo por el método de cuadrado centrado en un punto; el disturbio fue estimado a través de indicadores de sitio, y el estado de conservación de las poblaciones de Jatropha con el Método para la Evaluación de Riesgo de Extinción de Plantas en México (MER. Jatropha frecuentemente dominó la fisonomía de las comunidades vegetales. La distribución actual de las especies de Jatropha en la Reserva estuvo principalmente determinada por las variables altitud, temperatura y precipitación. Las especies confirmadas fueron: Jatropha ciliata Sessé ex Cerv., Jatropha neopauciflora Pax, Jatropha oaxacana J. Jiménez Ram. & R. Torres, Jatropha rufescens Brandegee, y Jatropha rzedowskii J. Jiménez Ram., las cuales estuvieron distribuidas en cuatro de las seis UA definidas. J. neopauciflora y J. rzedowskii son las especies más ampliamente distribuidas; estas últimas especies concurrieron en cuatro, J. oaxacana en dos, mientras que J. rufescens y J. ciliata en una UA, siendo ésta la especie más restringida. La riqueza de géneros en las comunidades asociadas varió entre 16 y 42. Los máximos y mínimos Índices de Valores de Importancia fueron observados en San Nicolás Tepoxtitlan para J. neopauciflora (53.75% y J. rzedowskii (1.50%. El

  15. Conducere apothecam, in qua exercere artem nostram: Το εργαστήριο ενός βυζαντινού και ενός βενετού ζωγράφου στην Κρήτη

    Directory of Open Access Journals (Sweden)

    Μαρία ΚΩΝΣΤΑΝΤΟΥΔΑΚΗ-ΚΙΤΡΟΜΗΛΙΔΟΥ

    2008-09-01

    Full Text Available Marie Constantoudaki-KitromilidesConducere apothecam,  in  qua exercere artem nostram. L'atelier d'un peintre byzantin et d'un peintre vénitien à CandieIl y a plus de trente ans, le père Mario Cattapan publia une première série de documents, provenant des Archives d'État de Venise et concernant des peintres ayant exercé en Crète de 1300 à 1500. Ce travail constitua un tournant important pour l'étude de la peinture dans l'île sous domination vénitienne. Depuis, des témoignages nouveaux ont éclairé l'activité d'artistes connus de la même époque; d'autres ont révélé les noms et l'activité d'artistes inconnus jusqu'à maintenant.La recherche du père Cattapan, ainsi que des documents étudiés par nous-même, ont apporté de données nouvelles sur l'activité du peintre Nicolaos Philanthropenos, habitant de Candie et probablement descendant d'une famille originaire de Constantinople. De ce dossier, nous publions et commentons ici une pièce rare.Il s'agit d'un contrat, rédigé dans la ville de Candie et daté du 23 novembre 1400, qui concerne la collaboration, sous forme de coopération professionelle (societas, entre Nicolaos Philantrhopenos et le peintre vénitien Nicolaus (Nicolò Storlado. Les deux artistes décident de louer ensemble une boutique pour exercer leur métier pendant une période de trois ans.L'analyse du document et son commentaire nous permettent de mieux comprendre l'activité du peintre Nicolaos Philanthropenos dans l'île de Crète mais aussi à Constantinople et à Venise. En effet, la production artistique de Philanthropenos s'étendait depuis les icônes byzatntines aux retables (pale d'altare de type occidental et aux mosaïques de Saint Marc de Venise. D'autre part, notre document éclaire les chemins de contact entre les peintres crétois et l'art vénitien. Le fonctionnement d'un atelier commun, tenu par deux peintres de formation et expérience culturelle différentes peut être interp

  16. Trends in HIV Terminology: Text Mining and Data Visualization Assessment of International AIDS Conference Abstracts Over 25 Years.

    Science.gov (United States)

    Dancy-Scott, Nicole; Dutcher, Gale A; Keselman, Alla; Hochstein, Colette; Copty, Christina; Ben-Senia, Diane; Rajan, Sampada; Asencio, Maria Guadalupe; Choi, Jason Jongwon

    2018-05-04

    "men who have sex with men" and "MSM" were rarely used until 1994; subsequently, use of these terms increased through 2014. The term "sex worker" steadily increased in frequency throughout conference years, whereas the term "prostitute" decreased over time. The results of this study highlight changes in HIV terminology use over 25 years, including the addition, disappearance, and changing use of terms that reflect advances in HIV research and medical practice and destigmatization of the disease. Coupled with findings from related quantitative research, HIV-related terminology recommendations based on results of this study are included. Adoption of these recommendations will further efforts to use less stigmatizing language and facilitate effective communication between health professionals and people affected by HIV. ©Nicole Dancy-Scott, Gale A Dutcher, Alla Keselman, Colette Hochstein, Christina Copty, Diane Ben-Senia, Sampada Rajan, Maria Guadalupe Asencio, Jason Jongwon Choi. Originally published in JMIR Public Health and Surveillance (http://publichealth.jmir.org), 04.05.2018.

  17. Interactive Two-Way mHealth Interventions for Improving Medication Adherence: An Evaluation Using The Behaviour Change Wheel Framework.

    Science.gov (United States)

    Chiang, Nicole; Guo, Michael; Amico, K Rivet; Atkins, Lou; Lester, Richard T

    2018-04-12

    evaluation of WelTel using the Behavior Change Wheel suggests that most of its impact is delivered primarily through its personalized communication component, in which 8 different behavior change techniques were identified and linked with 5 intervention functions (environmental restructuring, enablement, education, persuasion, and training). Its mechanisms of action in promoting antiretroviral therapy adherence may involve addressing all Capability Opportunity Motivation-Behavior influences on behavior (physical and psychological capability, physical and social opportunity, reflective and automatic motivation). Systematically unpacking the potential active ingredients of effective interventions facilitates the creation and implementation of more parsimonious, tailored, and targeted approaches. Evaluating WelTel using the Behavior Change Wheel has provided valuable insights into how and why such interactive two-way mHealth interventions may produce greater impact than one-way in addressing both nonintentional and intentional forms of nonadherence. The application of the Behavior Change Wheel for evidence synthesis across mHealth interventions targeting various conditions would contribute to strengthening the knowledge base regarding how they may work to impact medication adherence behavior. ©Nicole Chiang, Michael Guo, K Rivet Amico, Lou Atkins, Richard T Lester. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 12.04.2018.

  18. Editorial

    Directory of Open Access Journals (Sweden)

    The Editors

    2014-06-01

    Full Text Available Retention and persistence are at the forefront of attention by students, parents, and state and federal lawmakers.  We continue several decades of increasing education costs and the perception of steadily decreasing returns on investment of time and money required to achieve a higher education credential. Thus, a special issue devoted to retention is timely.  Included in this special issue of the Higher Learning Research Communications journal are a number of thought pieces and literature reviews that represent diverse perspectives on retention. Dr. Watson Scott Swail provides a provocative essay, A Different Viewpoint on Retention, in which he challenges readers to reflect on the key issues regarding retention of students. While he provides compelling statistics on the growing costs of getting a college degree, he reminds us that the core issue is one of student preparation. Dr. Swail also encourages institutions to determine what success means in its own context, through statistical analysis of predictors of retention and persistence whose results can be socialized at all who support students at the institution. Dr. Gary Burkholder and Nicole Holland provide an international perspective on retention and persistence. Through introductory analysis of the state of retention and persistence research in areas outside the United States, they encourage readers to think about retention more globally.  The authors ask the readers to consider how what we have learned about higher education, as well as retention and persistence, in the United States, can help researchers and practitioners to address higher education concerns in more meaningful and helpful ways. Dr. Rebecca Jobe and Jim Lenio then provide insight on retention and persistence research across student and institutional types as well as across educational sectors.  The authors convincingly suggest that retention is a concern that should provide a common ground for all institutions

  19. La aljama judía de Jaca en la época de la Disputa de Tortosa (1410-1420

    Directory of Open Access Journals (Sweden)

    Motis Dolader, Miguel Ángel

    1996-06-01

    consolidée dans laquelle les organes judiciaires etgouvernementaux, ces derniers sous la direction de trois adelantados, prennent de plus en plus d'importance. La société est divisée en troismains (majeure, moyenne et mineure, en fonction des critères fiscaux, où l'on perçoit la présence de corporations d'assistance. Dès le début du XVème siècle, le quartier juif commence à s'endetter et rassemble des fonds par le biais de souscriptions de redevance. Le quartier juif situé à l'origine entre la Portre de San Ginés et la Rue San Nicolás, subit un incendie ravageur en 1375 après lequel il fallut reconstruirepartiellemente les habitations. En ce qui concerne l'économie, la présencejuive a fortement marqué l'exploitation et la commercialisation de la laine et surtout l'industrie artisanale du cuir et de la chaussure. Dansl'appendice de cet ouvrage vous retrouverez les responsa du Rabbin Salamon ben Adret et Isaac ben Sheshet qui ont trait à ce Kahal.

  20. HealthyDads.ca: What Do Men Want in a Website Designed to Promote Emotional Wellness and Healthy Behaviors During the Transition to Parenthood?

    Science.gov (United States)

    Da Costa, Deborah; Zelkowitz, Phyllis; Letourneau, Nicole; Howlett, Andrew; Dennis, Cindy-Lee; Russell, Brian; Grover, Steven; Lowensteyn, Ilka; Chan, Peter; Khalifé, Samir

    2017-10-11

    stress (98/174, 56.3%). Perceiving the website as personally relevant (151/174, 86.8%), credible (141/174, 81.0%), effective (140/145, 80.5%), and having an easy navigation structure (141/174, 81.0%) were identified as important factors related to a first website visit. Providing useful (134/174, 77.0%) and easy to understand (158/174, 90.8%) information, which was also free of charge (156/174, 89.7%), were considered important for deciding to prolong a website visit. Providing the possibility to post questions to a health professional (133/174, 76.4%), adding new content regularly (119/174, 68.4%), and personal motivation (111/174, 63.8%) were factors identified that would encourage a revisit. Our findings demonstrate that there is substantial interest among expectant and new fathers for using Internet-delivered strategies to prepare for the transition to parenthood and support their mental health. Specific user and website features were identified to optimize the use of father-focused websites. ©Deborah Da Costa, Phyllis Zelkowitz, Nicole Letourneau, Andrew Howlett, Cindy-Lee Dennis, Brian Russell, Steven Grover, Ilka Lowensteyn, Peter Chan, Samir Khalifé. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 11.10.2017.