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Sample records for nick reese jennifer

  1. Síndrome iridocorneoendotelial: síndrome de Cogan Reese

    Directory of Open Access Journals (Sweden)

    Ana María Méndez Duque de Estrada

    Full Text Available El síndrome iridocorneoendotelial comprende entidades que presentan afectación del endotelio corneal, el iris y el ángulo de la cámara anterior, razón por la que se desarrolla el glaucoma. Es generalmente unilateral, progresivo y afecta con mayor frecuencia a los adultos del sexo femenino. Se describen tres variantes con sus características peculiares: atrofia esencial del iris, síndrome de Chandler y el síndrome de Cogan Reese, que es una entidad rara. Se presenta una mujer de 53 años con diagnóstico de síndrome de Cogan Reese de 6 años de evolución y glaucoma de difícil control, por lo que recibió tratamiento quirúrgico.

  2. Studying repair of a single protein-bound nick in vivo using the Flp-nick system

    DEFF Research Database (Denmark)

    Nielsen, Ida; Andersen, Anni Hangaard; Bjergbæk, Lotte

    2012-01-01

    The Flp-nick system is a simple in vivo system developed for studying the cellular responses to a protein-bound nick at a single genomic site in the budding yeast Saccharomyces cerevisiae. The Flp-nick system takes advantage of a mutant Flp recombinase that can introduce a nick at a specific Flp ...

  3. Nick Laws | NREL

    Science.gov (United States)

    -3238 Nick's primary work at NREL revolves around REopt - a techno-economic optimization model for , Nick is continuously adapting the REopt model to accommodate the latest technologies, market factors spiral and the impact of utility rate structures on the adoption of residential solar photovoltaics and

  4. Jennifer N. Markham | NREL

    Science.gov (United States)

    Jennifer.Markham@nrel.gov | 303-275-4154 Orcid ID http://orcid.org/0000-0003-0086-1559 Research Interests Techno Affiliated Research Programs Process Design, Modeling, and Economics Areas of Expertise Aspen Plus Process Biomass Fractionation to Lipid-and Carbohydrate-Derived Fuel Products, NREL Technical Report (2014) "

  5. Jennifer Salahub Presentation.pdf

    International Development Research Centre (IDRC) Digital Library (Canada)

    Karina Pena

    2015-05-13

    May 13, 2015 ... Urban Violence, Poverty, and Inequalities. Jennifer Salahub. Senior Program Officer, Governance and Justice ... function as a group. 3. Unpack how challenges can be efficiently addressed by the state working at multiple levels and in different configurations. 4. Engage with complexity and dynamism: five ...

  6. Phase 2 Reese River Geothermal Project Slim Well 56-4 Drilling and Testing

    Energy Technology Data Exchange (ETDEWEB)

    Henkle, William R.; Ronne, Joel

    2008-06-15

    This report covers the drilling and testing of the slim well 56-4 at the Reese River Geothermal Project in Lander County, Nevada. This well was partially funded through a GRED III Cooperative Funding Agreement # DE-FC36-04GO14344, from USDOE.

  7. Distinct genetic control of homologous recombination repair of Cas9-induced double-strand breaks, nicks and paired nicks

    NARCIS (Netherlands)

    Vriend, Lianne E. M.; Prakash, Rohit; Chen, Chun-Chin; Vanoli, Fabio; Cavallo, Francesca; Zhang, Yu; Jasin, Maria; Krawczyk, Przemek M.

    2016-01-01

    DNA double-strand breaks (DSBs) are known to be powerful inducers of homologous recombination (HR), but single-strand breaks (nicks) have also been shown to trigger HR. Both DSB- and nick-induced HR ((nick)HR) are exploited in advanced genome-engineering approaches based on the bacterial RNA-guided

  8. Uncovering Heroes: A Conversation with Jennifer Armstrong.

    Science.gov (United States)

    Kerper, Richard M.

    2000-01-01

    Offers an interview with Jennifer Armstrong, writer of historical novels and nonfiction for children. Discusses her beginnings as a reader and a writer, her creative process, her purposes in writing nonfiction, her concerns about accuracy, and the origins of her second nonfiction book, "Shipwreck at the Bottom of the World: The Extraordinary…

  9. Bypass of a nick by the replisome of bacteriophage T7.

    Science.gov (United States)

    Zhu, Bin; Lee, Seung-Joo; Richardson, Charles C

    2011-08-12

    DNA polymerase and DNA helicase are essential components of DNA replication. The helicase unwinds duplex DNA to provide single-stranded templates for DNA synthesis by the DNA polymerase. In bacteriophage T7, movement of either the DNA helicase or the DNA polymerase alone terminates upon encountering a nick in duplex DNA. Using a minicircular DNA, we show that the helicase · polymerase complex can bypass a nick, albeit at reduced efficiency of 7%, on the non-template strand to continue rolling circle DNA synthesis. A gap in the non-template strand cannot be bypassed. The efficiency of bypass synthesis depends on the DNA sequence downstream of the nick. A nick on the template strand cannot be bypassed. Addition of T7 single-stranded DNA-binding protein to the complex stimulates nick bypass 2-fold. We propose that the association of helicase with the polymerase prevents dissociation of the helicase upon encountering a nick, allowing the helicase to continue unwinding of the duplex downstream of the nick.

  10. Bypass of a Nick by the Replisome of Bacteriophage T7*

    Science.gov (United States)

    Zhu, Bin; Lee, Seung-Joo; Richardson, Charles C.

    2011-01-01

    DNA polymerase and DNA helicase are essential components of DNA replication. The helicase unwinds duplex DNA to provide single-stranded templates for DNA synthesis by the DNA polymerase. In bacteriophage T7, movement of either the DNA helicase or the DNA polymerase alone terminates upon encountering a nick in duplex DNA. Using a minicircular DNA, we show that the helicase·polymerase complex can bypass a nick, albeit at reduced efficiency of 7%, on the non-template strand to continue rolling circle DNA synthesis. A gap in the non-template strand cannot be bypassed. The efficiency of bypass synthesis depends on the DNA sequence downstream of the nick. A nick on the template strand cannot be bypassed. Addition of T7 single-stranded DNA-binding protein to the complex stimulates nick bypass 2-fold. We propose that the association of helicase with the polymerase prevents dissociation of the helicase upon encountering a nick, allowing the helicase to continue unwinding of the duplex downstream of the nick. PMID:21701044

  11. Roman for unge - og deres voksne - fra Nick Hornby

    DEFF Research Database (Denmark)

    Haarder, Jon Helt

    2007-01-01

    Nick Hornby: SLAM. Oversat fra engelsk. af Jan Hansen. 280 sider, 249 kr. Lindhardt og Ringhof. Fire stjerner Udgivelsesdato: 071207......Nick Hornby: SLAM. Oversat fra engelsk. af Jan Hansen. 280 sider, 249 kr. Lindhardt og Ringhof. Fire stjerner Udgivelsesdato: 071207...

  12. NCYM promotes calpain-mediated Myc-nick production in human MYCN-amplified neuroblastoma cells

    Energy Technology Data Exchange (ETDEWEB)

    Shoji, Wataru [Division of Biochemistry and Innovative Cancer Therapeutics and Children' s Cancer Research Center, Chiba Cancer Center Research Institute, 666-2 Nitona, Chuo-ku, Chiba 260-8717 (Japan); Department of Pediatric Surgery, Graduate School of Medicine, Tohoku University, Sendai 980-8574 (Japan); Suenaga, Yusuke, E-mail: ysuenaga@chiba-cc.jp [Division of Biochemistry and Innovative Cancer Therapeutics and Children' s Cancer Research Center, Chiba Cancer Center Research Institute, 666-2 Nitona, Chuo-ku, Chiba 260-8717 (Japan); Cancer Genome Center, Chiba Cancer Center Research Institute, 666-2 Nitona, Chuo-ku, Chiba 260-8717 (Japan); Kaneko, Yoshiki; Islam, S.M. Rafiqul; Alagu, Jennifer [Division of Biochemistry and Innovative Cancer Therapeutics and Children' s Cancer Research Center, Chiba Cancer Center Research Institute, 666-2 Nitona, Chuo-ku, Chiba 260-8717 (Japan); Yokoi, Sana [Cancer Genome Center, Chiba Cancer Center Research Institute, 666-2 Nitona, Chuo-ku, Chiba 260-8717 (Japan); Nio, Masaki [Department of Pediatric Surgery, Graduate School of Medicine, Tohoku University, Sendai 980-8574 (Japan); Nakagawara, Akira, E-mail: nakagawara-a@koseikan.jp [Division of Biochemistry and Innovative Cancer Therapeutics and Children' s Cancer Research Center, Chiba Cancer Center Research Institute, 666-2 Nitona, Chuo-ku, Chiba 260-8717 (Japan)

    2015-06-05

    NCYM is a cis-antisense gene of MYCN and is amplified in human neuroblastomas. High NCYM expression is associated with poor prognoses, and the NCYM protein stabilizes MYCN to promote proliferation of neuroblastoma cells. However, the molecular mechanisms of NCYM in the regulation of cell survival have remained poorly characterized. Here we show that NCYM promotes cleavage of MYCN to produce the anti-apoptotic protein, Myc-nick, both in vitro and in vivo. NCYM and Myc-nick were induced at G2/M phase, and NCYM knockdown induced apoptotic cell death accompanied by Myc-nick downregulation. These results reveal a novel function of NCYM as a regulator of Myc-nick production in human neuroblastomas. - Highlights: • NCYM promotes cleavages of MYC and MYCN to produce Myc-nick in vitro. • NCYM increases Myc-nick production in MYCN-amplified neuroblastoma cells. • NCYM knockdown decreases Myc-nick production and induces apoptosis at G2/M phase.

  13. NCYM promotes calpain-mediated Myc-nick production in human MYCN-amplified neuroblastoma cells

    International Nuclear Information System (INIS)

    Shoji, Wataru; Suenaga, Yusuke; Kaneko, Yoshiki; Islam, S.M. Rafiqul; Alagu, Jennifer; Yokoi, Sana; Nio, Masaki; Nakagawara, Akira

    2015-01-01

    NCYM is a cis-antisense gene of MYCN and is amplified in human neuroblastomas. High NCYM expression is associated with poor prognoses, and the NCYM protein stabilizes MYCN to promote proliferation of neuroblastoma cells. However, the molecular mechanisms of NCYM in the regulation of cell survival have remained poorly characterized. Here we show that NCYM promotes cleavage of MYCN to produce the anti-apoptotic protein, Myc-nick, both in vitro and in vivo. NCYM and Myc-nick were induced at G2/M phase, and NCYM knockdown induced apoptotic cell death accompanied by Myc-nick downregulation. These results reveal a novel function of NCYM as a regulator of Myc-nick production in human neuroblastomas. - Highlights: • NCYM promotes cleavages of MYC and MYCN to produce Myc-nick in vitro. • NCYM increases Myc-nick production in MYCN-amplified neuroblastoma cells. • NCYM knockdown decreases Myc-nick production and induces apoptosis at G2/M phase

  14. Footprinting of Chlorella virus DNA ligase bound at a nick in duplex DNA.

    Science.gov (United States)

    Odell, M; Shuman, S

    1999-05-14

    The 298-amino acid ATP-dependent DNA ligase of Chlorella virus PBCV-1 is the smallest eukaryotic DNA ligase known. The enzyme has intrinsic specificity for binding to nicked duplex DNA. To delineate the ligase-DNA interface, we have footprinted the enzyme binding site on DNA and the DNA binding site on ligase. The size of the exonuclease III footprint of ligase bound a single nick in duplex DNA is 19-21 nucleotides. The footprint is asymmetric, extending 8-9 nucleotides on the 3'-OH side of the nick and 11-12 nucleotides on the 5'-phosphate side. The 5'-phosphate moiety is essential for the binding of Chlorella virus ligase to nicked DNA. Here we show that the 3'-OH moiety is not required for nick recognition. The Chlorella virus ligase binds to a nicked ligand containing 2',3'-dideoxy and 5'-phosphate termini, but cannot catalyze adenylation of the 5'-end. Hence, the 3'-OH is important for step 2 chemistry even though it is not itself chemically transformed during DNA-adenylate formation. A 2'-OH cannot substitute for the essential 3'-OH in adenylation at a nick or even in strand closure at a preadenylated nick. The protein side of the ligase-DNA interface was probed by limited proteolysis of ligase with trypsin and chymotrypsin in the presence and absence of nicked DNA. Protease accessible sites are clustered within a short segment from amino acids 210-225 located distal to conserved motif V. The ligase is protected from proteolysis by nicked DNA. Protease cleavage of the native enzyme prior to DNA addition results in loss of DNA binding. These results suggest a bipartite domain structure in which the interdomain segment either comprises part of the DNA binding site or undergoes a conformational change upon DNA binding. The domain structure of Chlorella virus ligase inferred from the solution experiments is consistent with the structure of T7 DNA ligase determined by x-ray crystallography.

  15. A Conversation with Jennifer Buffett: The Power of Philanthropy to Transform Cultures

    Directory of Open Access Journals (Sweden)

    Riane Eisler

    2015-12-01

    Full Text Available IJPS Editor-in-Chief Riane Eisler talks with Jennifer Buffett, co-president of the NoVo Foundation, about her ideas, her life, and the role of philanthropy in the cultural transformation toward partnership.

  16. Nick Park pani Wallace'ile ja Gromitile libaküüliku needuse / Mart Rummo

    Index Scriptorium Estoniae

    Rummo, Mart

    2005-01-01

    Uus animafilm "Wallace ja Gromit : Libaküüliku needus" ("Wallace & Gromit : The Curse of the Were-Rabbit") : režissöör Nick Park : Suurbritannia 2005. Selle loojast ja tema loometeest. Lisatud : Nick Park (filmograafia, auhindu), "Teised Nick Parkist" (Lauri Kaare, Mait Laas, Riho Unt)

  17. Essays on the future in honor of Nick Metropolis

    CERN Document Server

    Rota, Gian-Carlo

    2000-01-01

    This collection represents a unique undertaking in scientific publishing to honor Nick Metropolis. Nick was the last survivor of the World War II Manhattan Project in Los Alamos, and was an important member of the Los Alamos national Laboratory until his death in October, 1999. In this volume, some of the leading scientists and humanists of our time have contributed essays related to their respective disciplines, exploring various aspects of future developments in science and society, philosophy, national security, nuclear power, pure and applied mathematics, physics and biology, particle physics, computing, and information science.

  18. Myc-nick: a cytoplasmic cleavage product of Myc that promotes alpha-tubulin acetylation and cell differentiation.

    Science.gov (United States)

    Conacci-Sorrell, Maralice; Ngouenet, Celine; Eisenman, Robert N

    2010-08-06

    The Myc oncoprotein family comprises transcription factors that control multiple cellular functions and are widely involved in oncogenesis. Here we report the identification of Myc-nick, a cytoplasmic form of Myc generated by calpain-dependent proteolysis at lysine 298 of full-length Myc. Myc-nick retains conserved Myc box regions but lacks nuclear localization signals and the bHLHZ domain essential for heterodimerization with Max and DNA binding. Myc-nick induces alpha-tubulin acetylation and altered cell morphology by recruiting histone acetyltransferase GCN5 to microtubules. During muscle differentiation, while the levels of full-length Myc diminish, Myc-nick and acetylated alpha-tubulin levels are increased. Ectopic expression of Myc-nick accelerates myoblast fusion, triggers the expression of myogenic markers, and permits Myc-deficient fibroblasts to transdifferentiate in response to MyoD. We propose that the cleavage of Myc by calpain abrogates the transcriptional inhibition of differentiation by full-length Myc and generates Myc-nick, a driver of cytoplasmic reorganization and differentiation. Copyright 2010 Elsevier Inc. All rights reserved.

  19. Review: Jennifer Browdy de Hernandez, Pauline Dongala, Omotayo Jolaosho and Anne Serafin (eds., African Women Writing Resistance: An Anthology of Contemporary Voices (2010 Buchbesprechung: Jennifer Browdy de Hernandez, Pauline Dongala, Omotayo Jolaosho und Anne Serafin (Hrsg., African Women Writing Resistance: An Anthology of Contemporary Voices (2010

    Directory of Open Access Journals (Sweden)

    Anja Oed

    2011-01-01

    Full Text Available Review of the edited volume: Jennifer Browdy de Hernandez, Pauline Dongala, Omotayo Jolaosho and Anne Serafin (eds., African Women Writing Resistance: An Anthology of Contemporary Voices, Oxford: Pambazuka Press, 2010, ISBN 978-0-299-23664-9, 376 pp.Besprechung des Sammelbandes: Jennifer Browdy de Hernandez, Pauline Dongala, Omotayo Jolaosho und Anne Serafin (Hrsg., African Women Writing Resistance: An Anthology of Contemporary Voices, Oxford: Pambazuka Press, 2010, ISBN 978-0-299-23664-9, 376 Seiten

  20. Making space: Jennifer Camper, LGBTQ anthologies, and queer comics communities.

    Science.gov (United States)

    Galvan, Margaret

    2018-05-04

    This article examines the career of lesbian cartoonist Jennifer Camper and how she has fostered queer community both in her comics and in real life. Archival research in LGBTQ archives and in Camper's own personal papers evidences how Camper begins developing her comics in the 1980s by participating in various grassroots LGBTQ publication spaces. From this foundation of support, she engages in comics activism with her representations of these communities during the midst of the AIDS crisis. Through these analyses, this article theorizes how Camper foregrounds intersectionality and counterpublics in her work on and off the page.

  1. An Appreciation and Analysis of "Edward Burtynsky--Manufactured Landscapes": A Film by Jennifer Baichwal

    Science.gov (United States)

    Donar, Ann

    2010-01-01

    This article begins with a synopsis of the film "Edward Burtynsky: Manufactured Landscapes", directed by Jennifer Baichwal. While the author can relate to the statements made in this synopsis, her experience and understanding of this 90-minute journey is much more intense and complex. In this essay, she attempts to dissect and examine…

  2. Divalent metal ion differentially regulates the sequential nicking reactions of the GIY-YIG homing endonuclease I-BmoI.

    Directory of Open Access Journals (Sweden)

    Benjamin P Kleinstiver

    Full Text Available Homing endonucleases are site-specific DNA endonucleases that function as mobile genetic elements by introducing double-strand breaks or nicks at defined locations. Of the major families of homing endonucleases, the modular GIY-YIG endonucleases are least understood in terms of mechanism. The GIY-YIG homing endonuclease I-BmoI generates a double-strand break by sequential nicking reactions during which the single active site of the GIY-YIG nuclease domain must undergo a substantial reorganization. Here, we show that divalent metal ion plays a significant role in regulating the two independent nicking reactions by I-BmoI. Rate constant determination for each nicking reaction revealed that limiting divalent metal ion has a greater impact on the second strand than the first strand nicking reaction. We also show that substrate mutations within the I-BmoI cleavage site can modulate the first strand nicking reaction over a 314-fold range. Additionally, in-gel DNA footprinting with mutant substrates and modeling of an I-BmoI-substrate complex suggest that amino acid contacts to a critical GC-2 base pair are required to induce a bottom-strand distortion that likely directs conformational changes for reaction progress. Collectively, our data implies mechanistic roles for divalent metal ion and substrate bases, suggesting that divalent metal ion facilitates the re-positioning of the GIY-YIG nuclease domain between sequential nicking reactions.

  3. La personalità della marca: validazione italiana della Brand Personality Scale di Jennifer Aaker

    OpenAIRE

    Fida Roberta; Sapere Domenico R.; Barbaranelli Claudio; Natali Elena

    2010-01-01

    This study focuses on the validation in the Italian context of the Brand Personality Scale developed by Jennifer Aaker. Five hundred and three Italians participated to this study. Bulgari's personality was assessed by means a questionnaire containing the Italian translation of the 42 traits of Aaker's Brand Personality Scale. Respondents rated how much each trait described Bulgari's personality. Results from exploratory and confirmatory factor analyses did not supported Aaker's Brand Personal...

  4. Pangahävitaja Leeson : "Ma kahetsen" / Nick Leeson ; interv. Argo Ideon

    Index Scriptorium Estoniae

    Leeson, Nick

    2007-01-01

    Briti börsimaakler Nick Leeson, kes pankrotistas Baringsi panga ning hävitas 17 miljardit krooni, selgitab, miks ta ei suutnud oma tegevust lõpetada ka siis kui kahjud olid kasvanud juba hiigelsuureks

  5. Trapping and breaking of in vivo nicked DNA during pulsed-field gel electrophoresis

    Science.gov (United States)

    Khan, Sharik R.; Kuzminov, Andrei

    2013-01-01

    Pulsed field gel electrophoresis (PFGE) offers a high-resolution approach to quantify chromosomal fragmentation in bacteria, measured as percent of chromosomal DNA entering the gel. The degree of separation in PFG depends upon the size of DNA, as well as various conditions of electrophoresis, such as electric field strength (FS), time of electrophoresis, switch time and buffer composition. Here we describe a new parameter, the structural integrity of the sample DNA itself, that influences its migration through PFGs. We show that sub-chromosomal fragments containing both spontaneous and DNA damage-induced nicks are prone to breakage during PFGE. Such breakage at single strand interruptions results in artefactual decrease in molecular weight of linear DNA making accurate determination of the number of double strand breaks difficult. While breakage of nicked sub-chromosomal fragments is FS-independent, some high molecular weight sub-chromosomal fragments are also trapped within wells under the standard PFGE conditions. This trapping can be minimized by lowering the field strength and increasing the time of electrophoresis. We discuss how breakage of nicked DNA may be mechanistically linked to trapping. Our results suggest how to optimize conditions for PFGE when quantifying chromosomal fragmentation induced by DNA damage. PMID:23770235

  6. Max Barry’s Jennifer Government and NationStates: neo-liberalism and the cultural public sphere = Jennifer Government, de Max Barry, e Estados-Nações: Neoliberalismo e a esfera pública da cultural

    Directory of Open Access Journals (Sweden)

    Purnima Bose

    2008-01-01

    Full Text Available In the United States, many people point to the corporatization of the media and the impoverishment of the public sphere as symptomatic of a crisis in democracy. While the mainstream media has not given much attention to popular anger against corporate globalization,literary works have started to explore this terrain, suggesting that the cultural public sphere is a parapolitical site for debates about economic neo-liberalism and its effects on people. This essayanalyzes the representation of neo-liberalism, corporate power, and resistance in Max Barry’s novel Jennifer Government and computer simulation game NationStates in the context of debates over globalization and the cultural public sphere.Muitas pessoas nos Estados Unidos alegam que a corporativismo dos meios de comunicação e o empobrecimento da esfera pública sãosintomas da crise na democracia. Enquanto os meios de comunicação principais não deram tanta importância à ira popular contra a globalização corporativa, muitos autores de obras literárias já começaram de analisar esse assunto. Sugerem que a esfera publica cultural é um lugar para-político para debates sobre o neoliberalismo econômico e suas conseqüências na população. Esse ensaio analisa a representação do neoliberalismo, poder corporativista e resistência no romance Jennifer Government, de Max Barry, e o jogo de computadorNationStates no contexto de debates sobre a globalização e a esfera pública cultural.

  7. Nick Ransford: 'There is a job to do so let's get on with it'.

    Science.gov (United States)

    Ransford, Nick; Doherty, Ruth

    2014-03-01

    Nick Ransford is a consultant in special care dentistry at Birmingham Community Healthcare NHS Trust. He has over 25 years' experience working with adults with disabilities and medical conditions across the spectrum.

  8. Nick translation detection in situ of cellular DNA strand break induced by radiation

    International Nuclear Information System (INIS)

    Maehara, Y.; Anai, H.; Kusumoto, T.; Sakaguchi, Y.; Sugimachi, K.

    1989-01-01

    DNA strand break in HeLa cells induced by radiation was detected using the in situ nick translation method. The cells were exposed to radiation of 3, 6, 12, 18, and 24 Gy in Lab-Tek tissue culture chamber/slides and were fixed with ethanol/acetic acid on the slide glass. The break sites in DNA were translated artificially in the presence of Escherichia coli DNA polymerase I and [ 3 H]-labeled dTTP. Autoradiographic observation was made of the level of break sites in the DNA. The DNA strand break appeared even with a 3 Gy exposure, increased 8.6 times at 24 Gy compared with the control cells, and this level correlated reciprocally to change in cell viability. This nick translation method provides a rapid in situ assay for determining radiation-induced DNA damage of cultured cells, in a semi-quantitative manner

  9. Nick Hornby’s A Long Way Down (2005 in the Transition from Book to Movie

    Directory of Open Access Journals (Sweden)

    Ömercan Tüm

    2015-12-01

    Full Text Available Nick Hornby’s A Long Way Down (2005 in the Transition from Book to movie Abstract Challenging and profound, Nick Hornby’s novel A Long Way Down (2005 is the story of four people failing to commit suicide. The protagonists are caught in an intricate web of relationships, disappointments and missed chances on their one-way journey to understand that “The cure for unhappiness is happiness” (Elizabeth McCracken. This paper aims at demonstrating that 2014 movie version directed by Pascal Chaumeil fails to capture the essence of the book and resorts to a number of radical changes which are only supposed to attract a larger audience, but do not necessarily send the same message as the novel.

  10. Metaphor or Method. Jennifer Mensch’s Organicist Kant Interpretation in Context

    Directory of Open Access Journals (Sweden)

    Günter Zöller

    2015-06-01

    Full Text Available In her recent study, Kant's Organicism.Epigenesis and the Development of Critical Philosophy (Chicago: Chicago University Press, 2013, Jennifer Mensch employs the technical term "organicism" to designate both Kant’s thinking about organisms and his thinking about other matters–chiefly among those transcendental cognition –in terms of his thinking about organisms. The article places Mensch's organicist reading of Kant into the wider context of recent and current work on Kant as a natural historian (Naturforscher and its repercussion for understanding the critical core of Kant’s philosophy. To that end, the article addresses the methodological function of conceptual metaphors in general and of biological metaphors in particular in Kant. The article proceeds in three steps, first focusing on an alleged anthropological turn in recent work on Kant, then addressing the distinction between schematism and symbolism in Kant’s critical epistemology and concluding with a consideration of the possibilities and limitations inherent in an organicist reading of Kant.

  11. Perspectives on the ‘lens of risk’ interview series: interview with Nick Pidgeon

    NARCIS (Netherlands)

    Heyman, B.; Brown, P.

    2012-01-01

    This article is the first in a series which will appear in 2012 in the special issue series Health Care Through the `Lens of Risk'. It provides a quasi-verbatim transcript of an interview with Nick Pidgeon, one of the main contributors to the social science component of The Royal Society Risk Report

  12. Nicked apomyoglobin: a noncovalent complex of two polypeptide fragments comprising the entire protein chain.

    Science.gov (United States)

    Musi, Valeria; Spolaore, Barbara; Picotti, Paola; Zambonin, Marcello; De Filippis, Vincenzo; Fontana, Angelo

    2004-05-25

    Limited proteolysis of the 153-residue chain of horse apomyoglobin (apoMb) by thermolysin results in the selective cleavage of the peptide bond Pro88-Leu89. The N-terminal (residues 1-88) and C-terminal (residues 89-153) fragments of apoMb were isolated to homogeneity and their conformational and association properties investigated in detail. Far-UV circular dichroism (CD) measurements revealed that both fragments in isolation acquire a high content of helical secondary structure, while near-UV CD indicated the absence of tertiary structure. A 1:1 mixture of the fragments leads to a tight noncovalent protein complex (1-88/89-153, nicked apoMb), characterized by secondary and tertiary structures similar to those of intact apoMb. The apoMb complex binds heme in a nativelike manner, as given by CD measurements in the Soret region. Second-derivative absorption spectra in the 250-300 nm region provided evidence that the degree of exposure of Tyr residues in the nicked species is similar to that of the intact protein at neutral pH. Also, the microenvironment of Trp residues, located in positions 7 and 14 of the 153-residue chain of the protein, is similar in both protein species, as given by fluorescence emission data. Moreover, in analogy to intact apoMb, the nicked protein binds the hydrophobic dye 1-anilinonaphthalene-8-sulfonate (ANS). Taken together, our results indicate that the two proteolytic fragments 1-88 and 89-153 of apoMb adopt partly folded states characterized by sufficiently nativelike conformational features that promote their specific association and mutual stabilization into a nicked protein species much resembling in its structural features intact apoMb. It is suggested that the formation of a noncovalent complex upon fragment complementation can mimic the protein folding process of the entire protein chain, with the difference that the folding of the complementary fragments is an intermolecular process. In particular, this study emphasizes the

  13. Securing wilderness landscapes in South Africa : Nick Steele, private wildlife conservancies and saving rhinos

    NARCIS (Netherlands)

    Wels,; H.,

    2015-01-01

    Private wildlife conservation is booming business in South Africa! Nick Steele stood at the cradle of this development in the politically turbulent 1970s and 1980s, by stimulating farmers in Natal (now KwaZulu-Natal) to pool resources in order to restore wilderness landscapes, but at the same time

  14. Dehalogenation of chloroalkanes by nickel(i) porphyrin derivatives, a computational study.

    Science.gov (United States)

    Szatkowski, L; Hall, M B

    2016-11-14

    The nickel(i) octaethylisobacteriochlorin anion ([OEiBCh-Ni (I) ] - ) is commonly used as a synthetic model of cofactor F 430 from Methyl-Coenzyme M Reductase. In this regard, experimental studies show that [OEiBCh-Ni (I) ] - can catalyze dehalogenation of aliphatic halides in DMF solution by a highly efficient S N 2 reaction. To better understand this process, we constructed theoretical models of the dehalogenation of chloromethane by a simple nickel(i) isobacteriochlorin anion and compared its reactivity with that of similar Ni (I) complexes with other porphyrin-derived ligands: porphyrin, chlorin, bactreriochlorin, hexahydroporphyrin and octahydroporphyrin. Our calculations predict that all of the porphyrin derivative's model reactions proceed through low-spin complexes. Relative to the energy of the separate reactants the theoretical activation energies (free-energy barriers with solvation corrections) for the dehalogenation of chloromethane are similar for all of the porphyrin derivatives and range for the different functionals from 10-15 kcal mol -1 for B3LYP to 5-10 kcal mol -1 for M06-L and to 13-18 kcal mol -1 for ωB97X-D. The relative free energies of the products of the dehalogenation step, L-Ni-Me adducts, have a range from -5 to -40 kcal mol -1 for all functionals; generally becoming more negative with increasing saturation of the porphyrin ligand. Moreover, no significant differences in the theoretical chlorine kinetic isotope effect were discernable with change of porphyrin ligand.

  15. Last stop on the road to repair: structure of E. coli DNA ligase bound to nicked DNA-adenylate.

    Science.gov (United States)

    Nandakumar, Jayakrishnan; Nair, Pravin A; Shuman, Stewart

    2007-04-27

    NAD(+)-dependent DNA ligases (LigA) are ubiquitous in bacteria and essential for growth. Their distinctive substrate specificity and domain organization vis-a-vis human ATP-dependent ligases make them outstanding targets for anti-infective drug discovery. We report here the 2.3 A crystal structure of Escherichia coli LigA bound to an adenylylated nick, which captures LigA in a state poised for strand closure and reveals the basis for nick recognition. LigA envelopes the DNA within a protein clamp. Large protein domain movements and remodeling of the active site orchestrate progression through the three chemical steps of the ligation reaction. The structure inspires a strategy for inhibitor design.

  16. Rhombic-Shaped Nanostructures and Mechanical Properties of 2D DNA Origami Constructed with Different Crossover/Nick Designs.

    Science.gov (United States)

    Ma, Zhipeng; Huang, Yunfei; Park, Seongsu; Kawai, Kentaro; Kim, Do-Nyun; Hirai, Yoshikazu; Tsuchiya, Toshiyuki; Yamada, Hirofumi; Tabata, Osamu

    2018-01-01

    DNA origami methods enable the fabrication of various nanostructures and nanodevices, but their effective use depends on an understanding of their structural and mechanical properties and the effects of basic structural features. Frequency-modulation atomic force microscopy is introduced to directly characterize, in aqueous solution, the crossover regions of sets of 2D DNA origami based on different crossover/nick designs. Rhombic-shaped nanostructures formed under the influence of flexible crossovers placed between DNA helices are observed in DNA origami incorporating crossovers every 3, 4, or 6 DNA turns. The bending rigidity of crossovers is determined to be only one-third of that of the DNA helix, based on interhelical electrostatic forces reported elsewhere, and the measured pitches of the 3-turn crossover design rhombic-shaped nanostructures undergoing negligible bending. To evaluate the robustness of their structural integrity, they are intentionally and simultaneously stressed using force-controlled atomic force microscopy. DNA crossovers are verified to have a stabilizing effect on the structural robustness, while the nicks have an opposite effect. The structural and mechanical properties of DNA origami and the effects of crossovers and nicks revealed in this paper can provide information essential for the design of versatile DNA origami structures that exhibit specified and desirable properties. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. Siim Nestor soovitab : Jus Fine ja DJ Hype. Mutant ja Nick Luscombe. Kuurorti kogumik / Siim Nestor

    Index Scriptorium Estoniae

    Nestor, Siim, 1974-

    2005-01-01

    Inglise drum'n'bass-staar DJ Hype 17. märtsil klubis Privé üritusel "Jus' Fine". Inglise diskor Nick Luscombe üritusel "Mutant" 18. märtsil klubis Privé. Plaadifirma Kuurortrecords esitleb 18. märtsil oma uut kogumikplaati Pirita jõe suudmes asuval laeval Monica

  18. An ultrasensitive colorimeter assay strategy for p53 mutation assisted by nicking endonuclease signal amplification.

    Science.gov (United States)

    Lin, Zhenyu; Yang, Weiqiang; Zhang, Guiyun; Liu, Qida; Qiu, Bin; Cai, Zongwei; Chen, Guonan

    2011-08-28

    A novel catalytic colorimetric assay assisted by nicking endonuclease signal amplification (NESA) was developed. With the signal amplification, the detection limit of the p53 target gene can be as low as 1 pM, which is nearly 5 orders of magnitude lower than that of other previously reported colorimetric DNA detection strategies based on catalytic DNAzyme.

  19. Review of James L. Baughman, Jennifer Ratner-Rosenhagen, and James P. Danky, eds, Protest on the Page: Essays on Print and the Culture of Dissent since 1865 (2015

    Directory of Open Access Journals (Sweden)

    Maria Zirra

    2017-12-01

    Full Text Available James L. Baughman, Jennifer Ratner-Rosenhagen, and James P. Danky, eds, Protest on the Page: Essays on Print and the Culture of Dissent since 1865 (Madison: University of Wisconsin Press, 2015. xv + 259 pp. ISBN 978-0-299-30284-9.

  20. DNA fragments assembly based on nicking enzyme system.

    Directory of Open Access Journals (Sweden)

    Rui-Yan Wang

    Full Text Available A couple of DNA ligation-independent cloning (LIC methods have been reported to meet various requirements in metabolic engineering and synthetic biology. The principle of LIC is the assembly of multiple overlapping DNA fragments by single-stranded (ss DNA overlaps annealing. Here we present a method to generate single-stranded DNA overlaps based on Nicking Endonucleases (NEases for LIC, the method was termed NE-LIC. Factors related to cloning efficiency were optimized in this study. This NE-LIC allows generating 3'-end or 5'-end ss DNA overlaps of various lengths for fragments assembly. We demonstrated that the 10 bp/15 bp overlaps had the highest DNA fragments assembling efficiency, while 5 bp/10 bp overlaps showed the highest efficiency when T4 DNA ligase was added. Its advantage over Sequence and Ligation Independent Cloning (SLIC and Uracil-Specific Excision Reagent (USER was obvious. The mechanism can be applied to many other LIC strategies. Finally, the NEases based LIC (NE-LIC was successfully applied to assemble a pathway of six gene fragments responsible for synthesizing microbial poly-3-hydroxybutyrate (PHB.

  1. The DNA Repair Repertoire of Mycobacterium smegmatis FenA Includes the Incision of DNA 5' Flaps and the Removal of 5' Adenylylated Products of Aborted Nick Ligation.

    Science.gov (United States)

    Uson, Maria Loressa; Ghosh, Shreya; Shuman, Stewart

    2017-09-01

    We characterize Mycobacterium smegmatis FenA as a manganese-dependent 5'-flap endonuclease homologous to the 5'-exonuclease of DNA polymerase I. FenA incises a nicked 5' flap between the first and second nucleotides of the duplex segment to yield a 1-nucleotide gapped DNA, which is then further resected in dinucleotide steps. Initial FenA cleavage at a Y-flap or nick occurs between the first and second nucleotides of the duplex. However, when the template 3' single strand is eliminated to create a 5'-tailed duplex, FenA incision shifts to between the second and third nucleotides. A double-flap substrate with a mobile junction (mimicking limited strand displacement synthesis during gap repair) is preferentially incised as the 1-nucleotide 3'-flap isomer, with the scissile phosphodiester shifted by one nucleotide versus a static double flap. FenA efficiently removes the 5' App(dN) terminus of an aborted nick ligation reaction intermediate, thereby highlighting FenA as an agent of repair of such lesions, which are formed under a variety of circumstances by bacterial NAD + -dependent DNA ligases and especially by mycobacterial DNA ligases D and C. IMPORTANCE Structure-specific DNA endonucleases are implicated in bacterial DNA replication, repair, and recombination, yet there is scant knowledge of the roster and catalytic repertoire of such nucleases in Mycobacteria This study identifies M. smegmatis FenA as a stand-alone endonuclease homologous to the 5'-exonuclease domain of mycobacterial DNA polymerase 1. FenA incises 5' flaps, 5' nicks, and 5' App(dN) intermediates of aborted nick ligation. The isolated N-terminal domain of M. smegmatis Pol1 is also shown to be a flap endonuclease. Copyright © 2017 American Society for Microbiology.

  2. Isothermal amplification detection of nucleic acids by a double-nicked beacon.

    Science.gov (United States)

    Shi, Chao; Zhou, Meiling; Pan, Mei; Zhong, Guilin; Ma, Cuiping

    2016-03-01

    Isothermal and rapid amplification detection of nucleic acids is an important technology in environmental monitoring, foodborne pathogen detection, and point-of-care clinical diagnostics. Here we have developed a novel method of isothermal signal amplification for single-stranded DNA (ssDNA) detection. The ssDNA target could be used as an initiator, coupled with a double-nicked molecular beacon, to originate amplification cycles, achieving cascade signal amplification. In addition, the method showed good specificity and strong anti-jamming capability. Overall, it is a one-pot and isothermal strand displacement amplification method without the requirement of a stepwise procedure, which greatly simplifies the experimental procedure and decreases the probability of contamination of samples. With its advantages, the method would be very useful to detect nucleic acids in point-of-care or field use. Copyright © 2015 Elsevier Inc. All rights reserved.

  3. Talking about Life

    Science.gov (United States)

    Impey, Chris

    2010-08-01

    Preface; Part I. Introduction Timothy Ferris, Iris Fry, Steven Dick, Ann Druyan, Pinky Nelson, Neil Tyson, Steve Benner and William Bains; Part II. Earth Roger Buick, Lynn Rothschild, John Baross, Joe Kirschvink, Andrew Knoll, Simon Conway Morris, Roger Hanlon and Lori Marino; Part III. Solar System Chris McKay, David Grinspoon, Jonathan Lunine, Carolyn Porco, Laurie Leshin, Guy Consolmagno and Peter Smith; Part IV. Exoplanets Alan Boss, Geoff Marcy, Debra Fischer, Sara Seager, David Charbonneau and Vikki Meadows; Part V. Frontiers Jill Tarter, Seth Shostak, Ray Kurzweil, Nick Bostrom, Paul Davies, Martin Rees, Ben Bova and Jennifer Michael Hecht; Reading list; Glossary; Index.

  4. Preparation and Characterization of Nicke-iron Alloy Film as Freestanding Electrode for Oxygen Evolution Reaction

    Directory of Open Access Journals (Sweden)

    Yao Mengqi

    2018-01-01

    Full Text Available This work reports the porous nicke-iron alloy film supported on stainless steel mesh as freestanding electrode for enhanced oxygen evolution reaction (OER catalyst prepared from an one step electrodeposition method. Results indicated that the porous nickle-iron alloy film exhibits a low overpotential of 270 mV at 10 mA cm-2 and excellent electroconductibility. The superior OER properties can be attributed to its novel synthetic process, conductive substrate and porous structure. This work will provide a new strategy to fabricate alloy film for OER electrocatalyst.

  5. The singer and the song: Nick Cave and the archetypal function of the cover version

    OpenAIRE

    Wiseman-Trowse, Nathan J B

    2013-01-01

    Throughout his career, from The Boys Next Door, through The Birthday Party, and with The Bad Seeds, Australian singer / songwriter Nick Cave has balanced his own set of creative voices alongside those of others through his choice of cover versions. Cave’s 1986 album with The Bad Seeds, ‘Kicking Against the Pricks’, is a collection of cover versions that spans American folk idioms (‘Black Betty’, ‘Hey Joe’, ‘The Singer’), Tin-Pan-Alley balladeering (‘Something’s Gotten Hold of my Heart’, ‘By t...

  6. W. Horsley Gantt, Nick, and the Pavlovian Science at Phipps Clinic.

    Science.gov (United States)

    Ruiz, Gabriel; Sánchez, Natividad

    2016-10-24

    William Horsley Gantt is well known as one to the principal proponents of Pavlovian methodology in the U.S. After a long stay at Ivan Petrovich Pavlov's laboratory in Leningrad from 1925 to 1929, Gantt was invited by Adolf Meyer to join the Henry Phipps Psychiatric Clinic, where he founded and directed the Pavlovian Laboratory from 1930 to 1964. Soon after his arrival at Phipps Clinic in 1931, Gantt began a Pavlovian research program that included the investigation of nervous disturbances in dogs and clinical researches with psychiatric patients. In these studies, Gantt combined a physiological method (the conditional reflexes approach), with a psychiatric problem (nervous disorders) in the context of Meyer's psychobiology that established the person or individual as unit of analysis. This fact, concentrating upon a single individual, made Gantt studies with dogs recognizable and interesting to physicians, psychologists, and psychiatrists who also worked on individuals. In this paper, we use archival materials -including correspondence, notebooks, and unpublished autobiographical material- to present a case study, that of William Horsley Gantt and his dog Nick. We will explore the reasons why Gantt' studies on nervous disturbances with this dog captured the interest of psychiatrists and clinical psychologists.

  7. On the use of an appropriate TdT-mediated dUTP-biotin nick end labeling assay to identify apoptotic cells.

    OpenAIRE

    Lebon, C.; Rodriguez, G.V.; Zaoui, I.E.; Jaadane, I.; Behar-Cohen, F.; Torriglia, A.

    2015-01-01

    Apoptosis is an essential cellular mechanism involved in many processes such as embryogenesis, metamorphosis, and tissue homeostasis. DNA fragmentation is one of the key markers of this form of cell death. DNA fragmentation is executed by endogenous endonucleases such as caspase-activated DNase (CAD) in caspase-dependent apoptosis. The TUNEL (TdT-mediated dUTP-biotin nick end labeling) technique is the most widely used method to identify apoptotic cells in a tissue or culture and to assess dr...

  8. Site- and strand-specific nicking of DNA by fusion proteins derived from MutH and I-SceI or TALE repeats.

    Science.gov (United States)

    Gabsalilow, Lilia; Schierling, Benno; Friedhoff, Peter; Pingoud, Alfred; Wende, Wolfgang

    2013-04-01

    Targeted genome engineering requires nucleases that introduce a highly specific double-strand break in the genome that is either processed by homology-directed repair in the presence of a homologous repair template or by non-homologous end-joining (NHEJ) that usually results in insertions or deletions. The error-prone NHEJ can be efficiently suppressed by 'nickases' that produce a single-strand break rather than a double-strand break. Highly specific nickases have been produced by engineering of homing endonucleases and more recently by modifying zinc finger nucleases (ZFNs) composed of a zinc finger array and the catalytic domain of the restriction endonuclease FokI. These ZF-nickases work as heterodimers in which one subunit has a catalytically inactive FokI domain. We present two different approaches to engineer highly specific nickases; both rely on the sequence-specific nicking activity of the DNA mismatch repair endonuclease MutH which we fused to a DNA-binding module, either a catalytically inactive variant of the homing endonuclease I-SceI or the DNA-binding domain of the TALE protein AvrBs4. The fusion proteins nick strand specifically a bipartite recognition sequence consisting of the MutH and the I-SceI or TALE recognition sequences, respectively, with a more than 1000-fold preference over a stand-alone MutH site. TALE-MutH is a programmable nickase.

  9. Repair of pyrimidine dimers in radiation-sensitive mutants rad3, rad4, rad6, and rad9 of Saccharomyces cerevisiae. [nicking

    Energy Technology Data Exchange (ETDEWEB)

    Prakash, L [Rochester Univ., N.Y. (USA). Dept. of Radiation Biology and Biophysics; Rochester Univ., N.Y. (USA). School of Medicine and Dentistry)

    1977-10-01

    The ability to remove ultraviolet-induced pyrimidine dimers was examined in four radiation-sensitive mutants of Saccharomyces cerevisiae. The susceptibility of DNA from irradiated cells to nicking by either the T4 uv-endonuclease or an endonuclease activity found in crude extracts of Micrococcus luteus was used to measure the presence of dimers in DNA. The rad3 and rad4 mutants are shown to be defective in dimer excision whereas the rad6 and rad9 mutants are proficient in dimer excision.

  10. Genome Editing in Mouse Spermatogonial Stem Cell Lines Using TALEN and Double-Nicking CRISPR/Cas9

    Directory of Open Access Journals (Sweden)

    Takuya Sato

    2015-07-01

    Full Text Available Mouse spermatogonial stem cells (SSCs can be cultured for multiplication and maintained for long periods while preserving their spermatogenic ability. Although the cultured SSCs, named germline stem (GS cells, are targets of genome modification, this process remains technically difficult. In the present study, we tested TALEN and double-nicking CRISPR/Cas9 on GS cells, targeting Rosa26 and Stra8 loci as representative genes dispensable and indispensable in spermatogenesis, respectively. Harvested GS cell colonies showed a high targeting efficiency with both TALEN and CRISPR/Cas9. The Rosa26-targeted GS cells differentiated into fertility-competent sperm following transplantation. On the other hand, Stra8-targeted GS cells showed defective spermatogenesis following transplantation, confirming its prime role in the initiation of meiosis. TALEN and CRISPR/Cas9, when applied in GS cells, will be valuable tools in the study of spermatogenesis and for revealing the genetic mechanism of spermatogenic failure.

  11. Processive nicking activity of T4 endonuclease V on UV-irradiated chromatin

    International Nuclear Information System (INIS)

    Gruskin, E.A.; Lloyd, R.S.

    1986-01-01

    T4 endonuclease V initiates the excision repair of pyrimidine dimers in UV-irradiated T4 infected E. coli cells. The pyrimidine dimer specific nicking activity of T4 endonuclease V functions by a processive scanning on UV-irradiated DNA. Previously it has been demonstrated that introduction of endonuclease V into repair-deficient human cells causes a restoration of UV survival in these cells. This demonstrates that endonuclease V is competent to incise mammalian DNA at the site of pyrimidine dimers. In order to assess the ability of endonuclease V to act processively on DNA associated as chromatin, minichromosomes were prepared for use as a substrate. Form I DNA was reconstituted with H3, H4 +/- H1 histones by sequential dialysis steps from 2.0 M NaCl to 50 mM NaCl. Time course reactions were performed with minichromosomes containing 10 and 25 dimers per molecule. In each case the rate of disappearance of form I DNA which was associated as chromatin was decreased relative to that of naked form I DNA. Concurrent with that observation, the rate and extent of appearance of form III DNA was increased with the DNA in minichromosomes relative to naked DNA. This is diagnostic of an enhancement of processivity. The inclusion of H1 in the minichromosomes resulted in a slight additional increase in processivity relative to minichromosomes consisting only of H3 and H4

  12. DNA gyrase with a single catalytic tyrosine can catalyze DNA supercoiling by a nicking-closing mechanism

    Science.gov (United States)

    Gubaev, Airat; Weidlich, Daniela; Klostermeier, Dagmar

    2016-01-01

    The topological state of DNA is important for replication, recombination and transcription, and is regulated in vivo by DNA topoisomerases. Gyrase introduces negative supercoils into DNA at the expense of ATP hydrolysis. It is the accepted view that gyrase achieves supercoiling by a strand passage mechanism, in which double-stranded DNA is cleaved, and a second double-stranded segment is passed through the gap, converting a positive DNA node into a negative node. We show here that gyrase with only one catalytic tyrosine that cleaves a single strand of its DNA substrate can catalyze DNA supercoiling without strand passage. We propose an alternative mechanism for DNA supercoiling via nicking and closing of DNA that involves trapping, segregation and relaxation of two positive supercoils. In contrast to DNA supercoiling, ATP-dependent relaxation and decatenation of DNA by gyrase lacking the C-terminal domains require both tyrosines and strand passage. Our results point towards mechanistic plasticity of gyrase and might pave the way for finding novel and specific mechanism-based gyrase inhibitors. PMID:27557712

  13. ISOLDE PH team, from left to right: Jennifer Weterings (user support), Susanne Kreim (research fellow), Marek Pfützner (scientific associate), Maria Garcia Borge (team leader), Elisa Rapisarda (research fellow) , Magdalena Kowalska (physics coordinator), Jan Kurcewicz (applied fellow), Monika Stachura (applied fellow). Not in the photo: Kara Lynch (PhD student).

    CERN Multimedia

    Visual Media Office

    2013-01-01

    ISOLDE PH team, from left to right: Jennifer Weterings (user support), Susanne Kreim (research fellow), Marek Pfützner (scientific associate), Maria Garcia Borge (team leader), Elisa Rapisarda (research fellow) , Magdalena Kowalska (physics coordinator), Jan Kurcewicz (applied fellow), Monika Stachura (applied fellow). Not in the photo: Kara Lynch (PhD student).

  14. Konstrukce vřeten vícevřetenového soustružnického automatu

    OpenAIRE

    Kráčmar, Tomáš

    2016-01-01

    Obsahem diplomové práce je konstrukce vřeten vícevřetenového soustružnického automatu pro práci z tyče maximálního průměru 7 mm. Práce se zabývá novou koncepcí pohonu vřeten, kde jsou vřetena poháněna externími asynchronními motory přes ozubená kola s vnitřním ozubením uložená vně vřetenového bubnu namísto současného způsobu pohonu centrálními koaxiálními hřídeli. Součástí práce je rešerše vícevřetenových automatů včetně popisu hlavních uzlů, konstrukční návrh, pevnostní výpočty, výpočty trva...

  15. FULL LENGTH RESEARCH ARTICLE Onuh & Ohazurike (2008 ...

    African Journals Online (AJOL)

    Dr. Ahmed

    flasks containing 50 ml of Reese and Levinson's solution, consisting of Sodium Polypectate (NaPP) as carbon source, and incubated for 7 days at 38oC. ... containing 50ml of Reese and Levinson's medium with Carboxylmethyl. Cellulose (CMC) as the .... from the brown rot fungus Postia placenta. Applied Microbiology and.

  16. 78 FR 22425 - Designation of Areas for Air Quality Planning Purposes; State of Nevada; Total Suspended Particulate

    Science.gov (United States)

    2013-04-16

    ... Valley, Fernley Area, Mason Valley, and Clovers Area. EPA is taking this action under the Clean Air Act... Reese Valley, Fernley Area, Mason Valley, and Clovers Area III. Final Action and Request for Comment IV... Reese Valley (HA 59), Gabbs Valley (HA 122), Fernley Area (HA 76), Truckee Meadows (HA 87), Mason Valley...

  17. An aptasensor for staphylococcus aureus based on nicking enzyme amplification reaction and rolling circle amplification.

    Science.gov (United States)

    Xu, Jingguo; Guo, Jia; Maina, Sarah Wanjiku; Yang, Yumeng; Hu, Yimin; Li, Xuanxuan; Qiu, Jiarong; Xin, Zhihong

    2018-05-15

    An ultra-sensitive aptamer-based biosensor for the detection of staphylococcus aureus was established by adopting the nicking enzyme amplification reaction (NEAR) and the rolling circle amplification (RCA) technologies. Aptamer-probe (AP), containing an aptamer and a probe sequence, was developed to act as the recognition unit of the biosensor, which was specifically bound to S. aureus. The probe was released from AP and initiated into the subsequent DNA amplification reactions where S. aureus was present, converting the detection of S. aureus to the investigation of probe oligonucleotide. The RCA amplification products contained a G-quadruplex motif and formed a three dimensional structure in presence of hemin. The G4/hemin complex showed horseradish peroxidase (HRP)-mimic activity and catalyzed the chemiluminescence reaction of luminol mediated by H 2 O 2 . The results showed that the established biosensor could detect S. aureus specifically with a good linear correlation at 5-10 4  CFU/mL. The signal values based on NEAR-RCA two-step cycle were boosted acutely, much higher than that relied on one-cycle magnification. The limit of detection (LoD) was determined to be as low as 5 CFU/mL. The established aptasensor exhibited a good discrimination of living against dead S. aureus, and can be applied to detect S. aureus in the food industry. Copyright © 2018 Elsevier Inc. All rights reserved.

  18. Optimization of a DNA Nicking Assay to Evaluate Oenocarpus bataua and Camellia sinensis Antioxidant Capacity

    Directory of Open Access Journals (Sweden)

    Louis-Jérôme Leba

    2014-10-01

    Full Text Available This study was aimed at assessing the DNA damage protective activity of different types of extracts (aqueous, methanolic and acetonic using an in vitro DNA nicking assay. Several parameters were optimized using the pUC18 plasmid, especially FeSO4, EDTA, solvent concentrations and incubation time. Special attention has been paid to removing the protective and damaging effect of the solvent and FeSO4 respectively, as well as to identifying the relevant positive and negative controls. For each solvent, the optimal conditions were determined: (i for aqueous extracts, 0.33 mM of FeSO4 and 0.62 mM of EDTA were incubated for 20 min at 37 °C; (ii for acetone extracts, 1.16% solvent were incubated for 15 min at 37 °C with 1.3 mM of FeSO4 and 2.5 mM of EDTA and (iii for methanol extracts, 0.16% solvent, were incubated for 1.5 h at 37 °C with 0.33 mM of FeSO4 and 0.62 mM of EDTA. Using the optimized conditions, the DNA damage protective activity of aqueous, methanolic and acetonic extracts of an Amazonian palm berry (Oenocarpus bataua and green tea (Camellia sinensis was assessed. Aqueous and acetonic Oenocarpus bataua extracts were protective against DNA damage, whereas aqueous, methanolic and acetonic extracts of Camellia sinensis extracts induced DNA damage.

  19. Remote Collaborative 3D Printing - Process Investigation

    Science.gov (United States)

    2016-04-01

    COLLABORATIVE 3D PRINTING - PROCESS INVESTIGATION Cody M. Reese, PE CAD MODEL PRINT MODEL PRINT PREVIEW PRINTED PART AERIAL VIRTUAL This...REMOTE COLLABORATIVE 3D PRINTING - PROCESS INVESTIGATION 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER Cody M. Reese...release; distribution is unlimited. 13. SUPPLEMENTARY NOTES 14. ABSTRACT The Remote Collaborative 3D Printing project is a collaboration between

  20. Ultrasensitive electrochemical biosensor for detection of DNA from Bacillus subtilis by coupling target-induced strand displacement and nicking endonuclease signal amplification.

    Science.gov (United States)

    Hu, Yuhua; Xu, Xueqin; Liu, Qionghua; Wang, Ling; Lin, Zhenyu; Chen, Guonan

    2014-09-02

    A simple, ultrasensitive, and specific electrochemical biosensor was designed to determine the given DNA sequence of Bacillus subtilis by coupling target-induced strand displacement and nicking endonuclease signal amplification. The target DNA (TD, the DNA sequence from the hypervarient region of 16S rDNA of Bacillus subtilis) could be detected by the differential pulse voltammetry (DPV) in a range from 0.1 fM to 20 fM with the detection limit down to 0.08 fM at the 3s(blank) level. This electrochemical biosensor exhibits high distinction ability to single-base mismatch, double-bases mismatch, and noncomplementary DNA sequence, which may be expected to detect single-base mismatch and single nucleotide polymorphisms (SNPs). Moreover, the applicability of the designed biosensor for detecting the given DNA sequence from Bacillus subtilis was investigated. The result obtained by electrochemical method is approximately consistent with that by a real-time quantitative polymerase chain reaction detecting system (QPCR) with SYBR Green.

  1. Nicking endonuclease-assisted signal amplification of a split molecular aptamer beacon for biomolecule detection using graphene oxide as a sensing platform.

    Science.gov (United States)

    Li, Xiang; Ding, Xuelian; Fan, Jing

    2015-12-07

    Sensitive and selective detection of ultralow concentrations of specific biomolecules is important in early clinical diagnoses and biomedical applications. Many types of aptasensors have been developed for the detection of various biomolecules, but usually suffer from false positive signals and high background signals. In this work, we have developed an amplified fluorescence aptasensor platform for ultrasensitive biomolecule detection based on enzyme-assisted target-recycling signal amplification and graphene oxide. By using a split molecular aptamer beacon and a nicking enzyme, the typical problem of false positive signals can be effectively resolved. Only in the presence of a target biomolecule, the sensor system is able to generate a positive signal, which significantly improves the selectivity of the aptasensor. Moreover, using graphene oxide as a super-quencher can effectively reduce the high background signal of a sensing platform. We select vascular endothelial growth factor (VEGF) and adenosine triphosphate (ATP) as model analytes in the current proof-of-concept experiments. It is shown that under optimized conditions, our strategy exhibits high sensitivity and selectivity for the quantification of VEGF and ATP with a low detection limit (1 pM and 4 nM, respectively). In addition, this biosensor has been successfully utilized in the analysis of real biological samples.

  2. 78 FR 48900 - Notice of Inventory Completion: State Historical Society of Wisconsin, Madison, WI

    Science.gov (United States)

    2013-08-12

    .... ADDRESSES: Jennifer Kolb, Wisconsin Historical Museum, 30 North Carroll Street, Madison, WI 53703, telephone (608) 261-2461, email Jennifer.Kolb@wisconsinhistory.org . SUPPLEMENTARY INFORMATION: Notice is here... request to Jennifer Kolb, Wisconsin Historical Museum, 30 North Carroll Street, Madison, WI 53703...

  3. 78 FR 44596 - Notice of Inventory Completion: State Historical Society of Wisconsin, Madison, WI

    Science.gov (United States)

    2013-07-24

    ... address in this notice by August 23, 2013. ADDRESSES: Jennifer Kolb, Wisconsin Historical Museum, 30 North Carroll Street, Madison, WI 53703, telephone (608) 261-2461, email Jennifer.Kolb@wisconsinhistory.org... request to Jennifer Kolb, Wisconsin Historical Museum, 30 North Carroll Street, Madison, WI 53703...

  4. DNA scanning mechanism of T4 endonuclease V. Effect of NaCl concentration on processive nicking activity

    International Nuclear Information System (INIS)

    Gruskin, E.A.; Lloyd, R.S.

    1986-01-01

    T4 endonuclease V is a pyrimidine dimer-specific endonuclease which generates incisions in DNA at the sites of pyrimidine dimers by a processive reaction mechanism. A model is presented in which the degree of processivity is directly related to the efficacy of the one-dimensional diffusion of endonuclease V on DNA by which the enzyme locates pyrimidine dimers. The modulation of the processive nicking activity of T4 endonuclease V on superhelical covalently closed circular DNA (form I) which contains pyrimidine dimers has been investigated as a function of the ionic strength of the reaction. Agarose gel electrophoresis was used to separate the three topological forms of the DNA which were generated in time course reactions of endonuclease V with dimer-containing form I DNA in the absence of NaCl, and in 25, 50, and 100 mM NaCl. The degree of processivity was evaluated in terms of the mass fraction of form III (linear) DNA which was produced as a function of the fraction of form I DNA remaining. Processivity is maximal in the absence of NaCl and decreases as the NaCl concentration is increased. At 100 mM NaCl, processivity is abolished and endonuclease V generates incisions in DNA at the site of dimers by a distributive reaction mechanism. The change from the distributive to a processive reaction mechanism occurs at NaCl concentrations slightly below 50 mM. The high degree of processivity which is observed in the absence of NaCl is reversible to the distributive mechanism, as demonstrated by experiments in which the NaCl concentration was increased during the time course reaction. In addition, unirradiated DNA inhibited the incision of irradiated DNA only at NaCl concentrations at which processivity was observed

  5. Jennifer Leavy and Colin Poulton

    African Journals Online (AJOL)

    commercialization means more than the marketing of agricultural output, it means the product choice ... is still live). However ... Livestock, aquaculture and other forms of agriculture are not within the scope of this paper, although the arguments ...

  6. Analysis of Apoptosis in Ultraviolet-Induced Sea Cucumber (Stichopus japonicus) Melting Using Terminal Deoxynucleotidyl-Transferase-Mediated dUTP Nick End-Labeling Assay and Cleaved Caspase-3 Immunohistochemistry.

    Science.gov (United States)

    Yang, Jing-Feng; Gao, Rong-Chun; Wu, Hai-Tao; Li, Peng-Fei; Hu, Xian-Shu; Zhou, Da-Yong; Zhu, Bei-Wei; Su, Yi-Cheng

    2015-11-04

    The sea cucumber body wall melting phenomenon occurs under certain circumstances, and the mechanism of this phenomenon remains unclear. This study investigated the apoptosis in the ultraviolet (UV)-induced sea cucumber melting phenomenon. Fresh sea cucumbers (Stichopus japonicus) were exposed to UV radiation for half an hour at an intensity of 0.056 mW/cm(2) and then held at room temperature for melting development. The samples were histologically processed into formalin-fixed paraffin-embedded tissues. The apoptosis of samples was analyzed with the terminal deoxynucleotidyl-transferase-mediated dUTP nick end-labeling (TUNEL) assay and cleaved caspase-3 immunohistochemistry. The emergence of TUNEL-positive cells speeds up between 0.5 and 2 h after UV irradiation. Cleaved caspase-3 positive cells were obviously detected in sample tissues immediately after the UV irradiation. These results demonstrated that sea cucumber melting induced by UV irradiation was triggered by the activation of caspase-3 followed by DNA fragmentation in sea cucumber tissue, which was attributed to apoptosis but was not a consequence of autolysis activity.

  7. Disability and deviance: Dario Argento's Phenomena and the maintenance of abledness as a critical framework.

    Science.gov (United States)

    McDaniel, Jamie L

    2013-12-01

    This exploration of disability directly applies Campbell's understanding of "abledness" to the film Phenomena by Italian director Dario Argento. Phenomena (1985) explores, through the diegetic response to protagonist Jennifer Corvino's ability to communicate with insects, the shifting cultural association between disability and deviance. The film begins with the traditional response to disability, what education psychologist Kaoru Yamamoto considers the cultural importance of classifying and interpreting disabled bodies by fitting them into a narrative of deviance for surveillance and control. Throughout Argento's film, characters attempt to classify Jennifer; scientists seek to diagnose her "affliction" through the medical model of disability, while Jennifer's schoolmistresses interpret Jennifer's behavior as a disciplinary problem based in environmental factors. This represents the structural model of disability, but in each instance, the attempt to classify Jennifer fails to diagnose or discipline the supposed "deviant, disabled body." Through this failure, the film dramatizes contemporary critiques of traditional models that examine disability, moving beyond to explore what Fiona Kumari Campbell has called "the maintenance of abledness" in sexed, raced, and modified bodies. By normalizing Jennifer's ability, then, Phenomena offers a framework for examining the process through which elements of "abledness" become normalized, a concept which many theorists now argue should maintain the focus of disability studies.

  8. 77 FR 39899 - Technical Corrections

    Science.gov (United States)

    2012-07-06

    ..., 2012. FOR FURTHER INFORMATION CONTACT: Jennifer Borges, Rules, Announcements, and Directives Branch..., Washington, DC 20555-0001, telephone: 301-492-3675, email: Jennifer.Borges@nrc.gov . ADDRESSES: Please refer...

  9. Freuds kvindelige bipersoner

    DEFF Research Database (Denmark)

    Lund, Jacob

    2014-01-01

    Anm. af Groce Smilevski: "Freuds søster" og Karen Mack og Jennifer Kaufman: "Freuds elskerinde"......Anm. af Groce Smilevski: "Freuds søster" og Karen Mack og Jennifer Kaufman: "Freuds elskerinde"...

  10. 77 FR 48538 - Notice of Inventory Completion: State Historical Society of Wisconsin, Madison, WI

    Science.gov (United States)

    2012-08-14

    ... Historical Society of Wisconsin at the address below by September 13, 2012. ADDRESSES: Jennifer Kolb... Indian tribe that believes it satisfies the criteria in 43 CFR 10.11(c)(1) should contact Jennifer Kolb...

  11. American Pain Society

    Science.gov (United States)

    ... Christopher King Jennifer Lee Kimberly Sibille Shivani Ruparel Steve Davidson Claudia Campbell Jennifer DeBerry Tim Doyle Adam ... Resources Early Career Advisory Group Members Early Career Job Board ECAG Application About Us Who's Who in ...

  12. Ljubov vtoroi svezhesti / Katja Tarhanova

    Index Scriptorium Estoniae

    Tarhanova, Katja

    2005-01-01

    Kaks uut ameerika melodraamat - "Oleks see ometi nii" ("Just Like Heaven") : režissöör Mike Waters : peaosas Reese Witherspoon ja "Prime" : stsenarist ja režissöör Ben Younger : peaosas Uma Thurman

  13. Joint research report for 1974--1975

    International Nuclear Information System (INIS)

    1976-01-01

    A general progress report is given on the research being carried out in the Biophysics Laboratory of the IIT Department of Physics and the Department of Medical Physics at Michael Reese Medical Center on pulse radiolysis experiments

  14. Functional Dissection of the DNA Interface of the Nucleotidyltransferase Domain of Chlorella Virus DNA Ligase*

    Science.gov (United States)

    Samai, Poulami; Shuman, Stewart

    2011-01-01

    Chlorella virus DNA ligase (ChVLig) has pluripotent biological activity and an intrinsic nick-sensing function. ChVLig consists of three structural modules that envelop nicked DNA as a C-shaped protein clamp: a nucleotidyltransferase (NTase) domain and an OB domain (these two are common to all DNA ligases) as well as a distinctive β-hairpin latch module. The NTase domain, which performs the chemical steps of ligation, binds the major groove flanking the nick and the minor groove on the 3′-OH side of the nick. Here we performed a structure-guided mutational analysis of the NTase domain, surveying the effects of 35 mutations in 19 residues on ChVLig activity in vivo and in vitro, including biochemical tests of the composite nick sealing reaction and of the three component steps of the ligation pathway (ligase adenylylation, DNA adenylylation, and phosphodiester synthesis). The results highlight (i) key contacts by Thr-84 and Lys-173 to the template DNA strand phosphates at the outer margins of the DNA ligase footprint; (ii) essential contacts of Ser-41, Arg-42, Met-83, and Phe-75 with the 3′-OH strand at the nick; (iii) Arg-176 phosphate contacts at the nick and with ATP during ligase adenylylation; (iv) the role of Phe-44 in forming the protein clamp around the nicked DNA substrate; and (v) the importance of adenine-binding residue Phe-98 in all three steps of ligation. Kinetic analysis of single-turnover nick sealing by ChVLig-AMP underscored the importance of Phe-75-mediated distortion of the nick 3′-OH nucleoside in the catalysis of DNA 5′-adenylylation (step 2) and phosphodiester synthesis (step 3). Induced fit of the nicked DNA into a distorted conformation when bound within the ligase clamp may account for the nick-sensing capacity of ChVLig. PMID:21335605

  15. Functional dissection of the DNA interface of the nucleotidyltransferase domain of chlorella virus DNA ligase.

    Science.gov (United States)

    Samai, Poulami; Shuman, Stewart

    2011-04-15

    Chlorella virus DNA ligase (ChVLig) has pluripotent biological activity and an intrinsic nick-sensing function. ChVLig consists of three structural modules that envelop nicked DNA as a C-shaped protein clamp: a nucleotidyltransferase (NTase) domain and an OB domain (these two are common to all DNA ligases) as well as a distinctive β-hairpin latch module. The NTase domain, which performs the chemical steps of ligation, binds the major groove flanking the nick and the minor groove on the 3'-OH side of the nick. Here we performed a structure-guided mutational analysis of the NTase domain, surveying the effects of 35 mutations in 19 residues on ChVLig activity in vivo and in vitro, including biochemical tests of the composite nick sealing reaction and of the three component steps of the ligation pathway (ligase adenylylation, DNA adenylylation, and phosphodiester synthesis). The results highlight (i) key contacts by Thr-84 and Lys-173 to the template DNA strand phosphates at the outer margins of the DNA ligase footprint; (ii) essential contacts of Ser-41, Arg-42, Met-83, and Phe-75 with the 3'-OH strand at the nick; (iii) Arg-176 phosphate contacts at the nick and with ATP during ligase adenylylation; (iv) the role of Phe-44 in forming the protein clamp around the nicked DNA substrate; and (v) the importance of adenine-binding residue Phe-98 in all three steps of ligation. Kinetic analysis of single-turnover nick sealing by ChVLig-AMP underscored the importance of Phe-75-mediated distortion of the nick 3'-OH nucleoside in the catalysis of DNA 5'-adenylylation (step 2) and phosphodiester synthesis (step 3). Induced fit of the nicked DNA into a distorted conformation when bound within the ligase clamp may account for the nick-sensing capacity of ChVLig.

  16. Pyrantel

    Science.gov (United States)

    Reese's® Pinworm Medicine ... antiworm medication, is used to treat roundworm, hookworm, pinworm, and other worm infections.This medication is sometimes ... usually is taken as a single dose for pinworm and roundworm infections. The dose usually is repeated ...

  17. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. JENNIFER DAVEY. Articles written in Journal of Genetics. Volume 96 Issue 4 September 2017 pp 681-685 RESEARCH NOTE. Clinical utility of a 377 gene custom next-generation sequencing epilepsy panel · JEN BEVILACQUA ANDREW HESSE BRIAN CORMIER JENNIFER DAVEY ...

  18. Calibration of resistance factors for drilled shafts for the new FHWA design method.

    Science.gov (United States)

    2013-01-01

    The Load and Resistance Factor Design (LRFD) calibration of deep foundation in Louisiana was first completed for driven piles (LTRC Final Report 449) in May 2009 and then for drilled shafts using 1999 FHWA design method (ONeill and Reese method) (...

  19. Military Interventions in Sierra Leone: Lessons from a Failed State

    National Research Council Canada - National Science Library

    Woods, Larry J; Reese, Timothy R

    2008-01-01

    This study by Larry J. Woods and Colonel Timothy R. Reese analyzes the massive turmoil afflicting the nation of Sierra Leone, 1993-2002, and the efforts by a variety of outside forces to bring lasting stability to that small country...

  20. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (80th, Chicago, Illinois, July 30-August 2, 1997): Communication Theory and Methodology.

    Science.gov (United States)

    Association for Education in Journalism and Mass Communication.

    The Communication Theory and Methodology section of the Proceedings contains the following 17 papers: "Extra! Extra! Read All About It: Attention and Memory for Deviant and Imagistic Headlines" (Jennifer Borse and others); "Refining a Uses and Gratification Scale for Television Viewing" (Jennifer Greer, Cyndi Frisby, and David…

  1. Book Reviews / Nick Ellison

    Index Scriptorium Estoniae

    Ellison, Nick

    2008-01-01

    J. Aidukaite doktoridissertatsiooni, The Emergence of the Post-Socialist Welfare State - The Case of the Baltic States: Estonia, Latvia and Lithuania, milles võrreldakse nende riikide sotsiaalpoliitikat ja sotsiaalabi süsteeme, refereering

  2. 78 FR 25422 - Antidumping or Countervailing Duty Order, Finding, or Suspended Investigation; Advance...

    Science.gov (United States)

    2013-05-01

    ... China (A-570-910) (1st 482-5047. Review). Carbon and Certain Alloy Steel Wire Rod from Jennifer Moats... Jennifer Moats (202) Mexico (A-201-830) (2nd Review). 482-5047. Carbon and Certain Alloy Steel Wire Rod... of China (C-570-911) (1st 482-4136. Review). [[Page 25423

  3. Scale-Independent Relational Query Processing

    Science.gov (United States)

    2013-10-04

    source options are also available, including Postgresql, MySQL , and SQLite. These mod- ern relational databases are generally very complex software systems...and Their Application to Data Stream Management. IGI Global, 2010. [68] George Reese. Database Programming with JDBC and Java , Second Edition. Ed. by

  4. TV Crime Reporter Missed Clues | NIH MedlinePlus the Magazine

    Science.gov (United States)

    ... my last." Jennifer now takes time to manage stress and nourish herself with healthy food. Jennifer urges all women to know their risk for heart disease and take action to lower it. "Women need to wake up," ... index). They need to watch their stress. "If the story of what I've been ...

  5. 76 FR 37291 - Food Labeling; Calorie Labeling of Articles of Food in Vending Machines; Correction

    Science.gov (United States)

    2011-06-27

    .... FDA-2011-F-0171] Food Labeling; Calorie Labeling of Articles of Food in Vending Machines; Correction... certain articles of food sold from vending machines. The document published with several errors including... FURTHER INFORMATION CONTACT: Daniel Y. Reese, Center for Food Safety and Applied Nutrition (HFS-820), Food...

  6. Relationship between Admission Selection Criteria and Academic Progression for Student Nurse Anesthetists

    Science.gov (United States)

    Burns, Sharon M.

    2009-01-01

    Today's admission selection criteria require refinement with the intention of fostering academic progression for students entering nurse anesthesia programs (Reese, 2002).With the escalating cost of graduate education coupled with the current economic crisis, efforts by educational leaders to minimize attrition remains pivotal (Andrews, Johansson,…

  7. US Military Nurses: Experience of Coming Home after Iraq and Afghanistan

    Science.gov (United States)

    2013-11-25

    1) Command Support, 2) reintegration briefings as Check the Blocks, 3) Stress of Being Home, 4) They Dont Understand if they havent deployed and 5...Investigator: Rivers, Felecia USU Project Number: N10-C05 19 Poster Presentations Authors: Rivers, F., Gordon, S., Speraw, S., Reese, S., Wilson

  8. Applying Modern Stage Theory to Mauritania: A Prescription to Encourage Entrepreneurship

    Science.gov (United States)

    2014-12-01

    STAGE THEORY TO MAURITANIA: A PRESCRIPTION TO ENCOURAGE ENTREPRENEURSHIP by Jennifer M. Warren December 2014 Thesis Advisor: Robert E...PRESCRIPTION TO ENCOURAGE ENTREPRENEURSHIP 5. FUNDING NUMBERS 6. AUTHOR(S) Jennifer M. Warren 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Naval...a chapter in which Dr. Looney relates modern stage theory to emerging economies. With an understanding that entrepreneurship is key for sustained

  9. Characterizing Musculoskeletal Injury among Aeromedical Evacuation Personnel: An Observational Study

    Science.gov (United States)

    2016-09-28

    Jennifer Serres, PhD; Col Susan Dukes, PhD; Molly Wade, MS; Brittany Fouts, MS; Mandy Cowgill, MS; Daniel Pohlman, BS September 2016...CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Jennifer Serres, Susan Dukes, Molly Wade, Brittany Fouts, Mandy... environment . 2.0 INTRODUCTION Musculoskeletal injuries (MSIs) result from the cumulative trauma associated with repetitive and physically

  10. Once a physicist: Nick Horvath

    Science.gov (United States)

    Horvath, Nick

    2009-05-01

    How did you get into basketball? That's an easy one: I was tall. I had zero interest in sport at a young age and was pushed into basketball against my will when I was about eight. I hated it. The next year, however, I was so much taller than everyone else that in my first game, even though I had no idea what I was doing, I could simply hold the ball above my head and shoot over everyone. I fell in love with basketball after that first game. If I had played badly that day, it is likely that I would not have played again in my entire life.

  11. Ice Storms in a Changing Climate

    Science.gov (United States)

    2016-06-01

    CHANGING CLIMATE by Jennifer M. McNitt June 2016 Thesis Advisor: Wendell Nuss Co-Advisor: David W. Titley THIS PAGE INTENTIONALLY LEFT...SUBTITLE ICE STORMS IN A CHANGING CLIMATE 5. FUNDING NUMBERS 6. AUTHOR(S) Jennifer M. McNitt 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS...increase in global temperatures, due to climate change, could affect the frequency, intensity, and geographic location of ice storms. Three known ice

  12. The Role of IDO in Muc1 Targeted Immunotherapy

    Science.gov (United States)

    2013-01-01

    Besmer*, Teresa L. Tinder , Lopamudra Das Roy, Joseph Lustgarten, Sandra J. Gendler, Pinku Mukherjee Intratumoral Delivery of CpG-Conjugated Anti...3073-87. Epub 2012 Jan 11. PMID: 22238308 3. Mahnaz Sahraei , Lopamudra Das Roy , Jennifer Curry , Teresa Tinder , Sritama Nath , Dahlia M...10.1038/onc.2011.651 4. Dahlia M. Besmer , Dr. Jennifer M. Curry , Dr. Lopamudra D. Roy , Ms. Teresa L. Tinder , Ms. Mahnaz M. Sahraei , Dr

  13. Report on a Boston University Conference December 7-8, 2012 on "How Can the History and Philosophy of Science Contribute to Contemporary US Science Teaching?"

    Science.gov (United States)

    Garik, Peter; Benétreau-Dupin, Yann

    2014-01-01

    This is an editorial report on the outcomes of an international conference sponsored by a grant from the National Science Foundation (NSF) (REESE-1205273) to the School of Education at Boston University and the Center for Philosophy and History of Science at Boston University for a conference titled: "How Can the History and Philosophy of…

  14. 2020 Vision: Envisioning a New Generation of STEM Learning Research

    Science.gov (United States)

    Dierking, Lynn D.; Falk, John H.

    2016-01-01

    In this issue, we have compiled six original papers, outcomes from the U.S. National Science Foundation (US-NSF)-funded REESE (Research and Evaluation on Education in Science and Engineering) 2020 Vision: The Next Generation of STEM Learning Research project. The purpose of 2020 Vision was to re-envision the questions and frameworks guiding STEM…

  15. Structure-function analysis of the OB and latch domains of chlorella virus DNA ligase.

    Science.gov (United States)

    Samai, Poulami; Shuman, Stewart

    2011-06-24

    Chlorella virus DNA ligase (ChVLig) is a minimized eukaryal ATP-dependent DNA sealing enzyme with an intrinsic nick-sensing function. ChVLig consists of three structural domains, nucleotidyltransferase (NTase), OB-fold, and latch, that envelop the nicked DNA as a C-shaped protein clamp. The OB domain engages the DNA minor groove on the face of the duplex behind the nick, and it makes contacts to amino acids in the NTase domain surrounding the ligase active site. The latch module occupies the DNA major groove flanking the nick. Residues at the tip of the latch contact the NTase domain to close the ligase clamp. Here we performed a structure-guided mutational analysis of the OB and latch domains. Alanine scanning defined seven individual amino acids as essential in vivo (Lys-274, Arg-285, Phe-286, and Val-288 in the OB domain; Asn-214, Phe-215, and Tyr-217 in the latch), after which structure-activity relations were clarified by conservative substitutions. Biochemical tests of the composite nick sealing reaction and of each of the three chemical steps of the ligation pathway highlighted the importance of Arg-285 and Phe-286 in the catalysis of the DNA adenylylation and phosphodiester synthesis reactions. Phe-286 interacts with the nick 5'-phosphate nucleotide and the 3'-OH base pair and distorts the DNA helical conformation at the nick. Arg-285 is a key component of the OB-NTase interface, where it forms a salt bridge to the essential Asp-29 side chain, which is imputed to coordinate divalent metal catalysts during the nick sealing steps.

  16. Structure-Function Analysis of the OB and Latch Domains of Chlorella Virus DNA Ligase*

    Science.gov (United States)

    Samai, Poulami; Shuman, Stewart

    2011-01-01

    Chlorella virus DNA ligase (ChVLig) is a minimized eukaryal ATP-dependent DNA sealing enzyme with an intrinsic nick-sensing function. ChVLig consists of three structural domains, nucleotidyltransferase (NTase), OB-fold, and latch, that envelop the nicked DNA as a C-shaped protein clamp. The OB domain engages the DNA minor groove on the face of the duplex behind the nick, and it makes contacts to amino acids in the NTase domain surrounding the ligase active site. The latch module occupies the DNA major groove flanking the nick. Residues at the tip of the latch contact the NTase domain to close the ligase clamp. Here we performed a structure-guided mutational analysis of the OB and latch domains. Alanine scanning defined seven individual amino acids as essential in vivo (Lys-274, Arg-285, Phe-286, and Val-288 in the OB domain; Asn-214, Phe-215, and Tyr-217 in the latch), after which structure-activity relations were clarified by conservative substitutions. Biochemical tests of the composite nick sealing reaction and of each of the three chemical steps of the ligation pathway highlighted the importance of Arg-285 and Phe-286 in the catalysis of the DNA adenylylation and phosphodiester synthesis reactions. Phe-286 interacts with the nick 5′-phosphate nucleotide and the 3′-OH base pair and distorts the DNA helical conformation at the nick. Arg-285 is a key component of the OB-NTase interface, where it forms a salt bridge to the essential Asp-29 side chain, which is imputed to coordinate divalent metal catalysts during the nick sealing steps. PMID:21527793

  17. C-terminal phenylalanine of bacteriophage T7 single-stranded DNA-binding protein is essential for strand displacement synthesis by T7 DNA polymerase at a nick in DNA.

    Science.gov (United States)

    Ghosh, Sharmistha; Marintcheva, Boriana; Takahashi, Masateru; Richardson, Charles C

    2009-10-30

    Single-stranded DNA-binding protein (gp2.5), encoded by gene 2.5 of bacteriophage T7, plays an essential role in DNA replication. Not only does it remove impediments of secondary structure in the DNA, it also modulates the activities of the other replication proteins. The acidic C-terminal tail of gp2.5, bearing a C-terminal phenylalanine, physically and functionally interacts with the helicase and DNA polymerase. Deletion of the phenylalanine or substitution with a nonaromatic amino acid gives rise to a dominant lethal phenotype, and the altered gp2.5 has reduced affinity for T7 DNA polymerase. Suppressors of the dominant lethal phenotype have led to the identification of mutations in gene 5 that encodes the T7 DNA polymerase. The altered residues in the polymerase are solvent-exposed and lie in regions that are adjacent to the bound DNA. gp2.5 lacking the C-terminal phenylalanine has a lower affinity for gp5-thioredoxin relative to the wild-type gp2.5, and this affinity is partially restored by the suppressor mutations in DNA polymerase. gp2.5 enables T7 DNA polymerase to catalyze strand displacement DNA synthesis at a nick in DNA. The resulting 5'-single-stranded DNA tail provides a loading site for T7 DNA helicase. gp2.5 lacking the C-terminal phenylalanine does not support this event with wild-type DNA polymerase but does to a limited extent with T7 DNA polymerase harboring the suppressor mutations.

  18. C-terminal Phenylalanine of Bacteriophage T7 Single-stranded DNA-binding Protein Is Essential for Strand Displacement Synthesis by T7 DNA Polymerase at a Nick in DNA*

    Science.gov (United States)

    Ghosh, Sharmistha; Marintcheva, Boriana; Takahashi, Masateru; Richardson, Charles C.

    2009-01-01

    Single-stranded DNA-binding protein (gp2.5), encoded by gene 2.5 of bacteriophage T7, plays an essential role in DNA replication. Not only does it remove impediments of secondary structure in the DNA, it also modulates the activities of the other replication proteins. The acidic C-terminal tail of gp2.5, bearing a C-terminal phenylalanine, physically and functionally interacts with the helicase and DNA polymerase. Deletion of the phenylalanine or substitution with a nonaromatic amino acid gives rise to a dominant lethal phenotype, and the altered gp2.5 has reduced affinity for T7 DNA polymerase. Suppressors of the dominant lethal phenotype have led to the identification of mutations in gene 5 that encodes the T7 DNA polymerase. The altered residues in the polymerase are solvent-exposed and lie in regions that are adjacent to the bound DNA. gp2.5 lacking the C-terminal phenylalanine has a lower affinity for gp5-thioredoxin relative to the wild-type gp2.5, and this affinity is partially restored by the suppressor mutations in DNA polymerase. gp2.5 enables T7 DNA polymerase to catalyze strand displacement DNA synthesis at a nick in DNA. The resulting 5′-single-stranded DNA tail provides a loading site for T7 DNA helicase. gp2.5 lacking the C-terminal phenylalanine does not support this event with wild-type DNA polymerase but does to a limited extent with T7 DNA polymerase harboring the suppressor mutations. PMID:19726688

  19. Choosing a Global Positioning System Device for Use in U.S. Army Corps of Engineers Regulatory Districts

    Science.gov (United States)

    2017-12-01

    ERDC) solves the nation’s toughest engineering and environmental challenges. ERDC develops innovative solutions in civil and military engineering ...communication with Jennifer Goulet via email. 5 September. Washington, DC: U.S. Army Corps of Engineers Civil Works, Geospatial Community of Practice...of Engineers Regulatory Districts Co ld R eg io ns R es ea rc h an d En gi ne er in g La bo ra to ry Jennifer J. Goulet, Lindsey E. Lefebvre

  20. The Next Supreme Leader: Succession in the Islamic Republic Of Iran

    Science.gov (United States)

    2011-01-01

    E. Thaler, Nora Bensahel, Kim Cragin, Jerrold D. Green, Dalia Dassa Kaye, Nadia Oweidat, and Jennifer Li , Dangerous But Not Omnipotent: Exploring...Janeshin Namayand e Vali e Faghih dar Sepah, ya Sokhanguy e Hezb e Siyasi Neza- mian ? [The Deputy Representative of the Supreme Leader in the Guards...Dassa Kaye, Nadia Oweidat, and Jennifer Li , Dangerous But Not Omnipotent: Exploring the Reach and Limitations of Iranian Power in the Middle East, Santa

  1. Модели, объясняющие здоровье и болезни: неожиданности при взгляде изнутри бывшего Советского Союза

    OpenAIRE

    Tatiana, I.

    2013-01-01

    The review of anthropological theories as applied to public health by Jennifer J. Carroll (Carroll, 2013) published in this issue of TCPHEE made me recollect my first and most surprising discoveries of how differently same things can be understood in different parts of the world. Probably less unexpectedly, these impressions concern substance abuse and addiction behaviors, similarly to many examples deployed by Jennifer J. Carroll. The first of these events happened soon after the break-up of...

  2. A Novel Approach to Adaptive Flow Separation Control

    Science.gov (United States)

    2016-09-03

    Artificial Intelligence ( ) TOTAL: 1 Books Number of Manuscripts: Patents Submitted Patents Awarded Awards Graduate Students Names of Post Doctorates...Education, February 2015. ASME Fellow, April 2013. Received Book TOTAL: Received Book Chapter TOTAL: PERCENT_SUPPORTEDNAME FTE Equivalent: Total Number...and other fields such as power system control and automotive engine tuning. References 1. B. Reese, F. Alvi, and E. G. Collins, “A

  3. Process and representation in multiple-cue judgment

    OpenAIRE

    Olsson, Anna-Carin

    2002-01-01

    This thesis investigates the cognitive processes and representations underlying human judgment in a multiple-cue judgment task. Several recent models assume that people have several qualitatively distinct and competing levels of knowledge representations (Ashby, Alfonso-Reese, Turken, & Waldron, 1998; Erickson & Kruschke, 1998; Nosofsky, Palmeri, & McKinley, 1994; Sloman, 1996). The most successful cognitive models in categorization and multiple-cue judgment are, respectively, exe...

  4. Internet-Based Cognitive Behavioral Therapy Effects on Depressive Cognitive and Brain Function

    Science.gov (United States)

    2013-03-01

    disorder. Biological Psychiatry, 50, 659-67. REESE, T. G., HEID, O., WEISSKOFF, R. M. & WEDEEN, V. J. 2003. Reduction of eddy-current- induced distortion...No ___ Yes Hirsuitism (excessive hair growth, especially on face) ___ No ___ Yes Amenorrhea ...PHYSICAL INFORMATION Do you engage in regular exercise : YES NO If ‘YES’: How many days per week do you exercise (circle one)? 1 2

  5. Internet-Based Cognitive Behavioral Therapy Effects on Depressive Cognitions and Brain Function

    Science.gov (United States)

    2014-03-01

    67. REESE, T. G., HEID, O., WEISSKOFF, R. M. & WEDEEN, V. J. 2003. Reduction of eddy-current- induced distortion in diffusion MRI using a twice...No ___ Yes Amenorrhea (> 3 months without a period when not pregnant) ___ No ___ Yes Galactorrhea (Breast milk...How often? _____________ PHYSICAL INFORMATION Do you engage in regular exercise : YES NO If ‘YES’: How many days per week do

  6. Army Strategic Leader Competency Development: Small Changes for a Large Impact

    Science.gov (United States)

    2013-03-01

    an Infantry Officer is similar to other Maneuver, Fire, and Effects ( MFE ) Officers, and the majority of General Officers come for the MFE ranks.24...Army, CASAL 2010, 12. 65 Discussion with COL Reese Turner, Former MFE Branch Chief, 13 Nov 12, on how branches assign officers to OES assignments. 66 U.S. Department of the Army, CASAL 2010, 18.

  7. Seamless Integration of Detection and Therapy for Breast Cancer using Targeted Engineered Nanoparticles

    Science.gov (United States)

    2008-06-01

    SERS Signal Reporters," Anal. Chem. (2006). 19. Choi, M.-R.; Stanton-Maxey, K. J.; Stanley, J. K.; Levin, C. S.; Bardhan , R.; Akin, D.; Badve, S... Bardhan , R.; Akin, D.; Badve, S.; Sturgis, J.; Robinson, J. P.; Bashir, R.; Halas, N. J.; Clare, S. E. A Cellular Trojan Horse for Delivery of...Stanton-Maxey,† Jennifer K. Stanley,† Carly S. Levin,‡,§ Rizia Bardhan ,‡,§ Demir Akin,| Sunil Badve,⊥ Jennifer Sturgis,# J. Paul Robinson,# Rashid

  8. Disposal and Reuse of Wurtsmith Air Force Base, Michigan. Environmental Impact Statement

    Science.gov (United States)

    1989-09-01

    can enter a building through small spaces and openings, accumulating in enclosed areas, such as basements. The cancer risk caused by exposure, through...onviramentai concerns with the Proposed alternative, and the *26 mama 4addtiesal informationes Laecessary to rolly Reese. all is~actM. OWr COMes...exposure that have been studied include birth defects, low birth weight, psychological illness, cancer , stroke, hypertension, sudden cardiac death

  9. Bibliography of Technical Publications and Papers, October 1979 - September 1980

    Science.gov (United States)

    1980-11-01

    technological procedures affecting quality of radappertized chicken rolls. Institute of Food Technolo- gists, New Orleans, LA, 9-11 June 1980. 93...temperature survey of ginger beef pot roast production at a Central Food Preparation Facility. J. Food Prot., 43(4): 292-294 (1980). 180. REESE, E. T...low-dose irradiated chicken skins. Interagency Botulism Research Coordinating Coummittee, Milford, CT, 8-9 October 1980. 207. CALLO, B. Protoplast

  10. Wrox SharePoint 2010 SharePoint911 three-pack

    CERN Document Server

    Klindt, Todd; Mason, Jennifer; Rogers, Laura; Drisgill, Randy; Ross, John; Riemann, Larry; Perran, Amanda; Perran, Shane; Sanford, Jacob J; Stubbs, Paul; Caravajal, Steve

    2012-01-01

    The Wrox SharePoint 2010 SharePoint911 Three-Pack combines the contents of three full e-books written by the experts from SharePoint911.  That's over 1800 pages of hands-on advice from Todd Klindt, Shane Young, Laura Rogers, Randy Drisgill, Jennifer Mason, John Ross, and Larry Riemann, among others. In Beginning SharePoint 2010: Building Business Solutions with SharePoint (ISBN 978-0-470-61789-2) by Amanda Perran, Shane Perran, Jennifer Mason, and Laura Rogers, readers learn the core concepts, terminology, and features of SharePoint 2010. In Professiona

  11. Site-specifically modified oligodeoxyribonucleotides as templates for Escherichia coli DNA polymerase I

    International Nuclear Information System (INIS)

    O'Connor, D.; Stoehrer, G.

    1985-01-01

    Oligodeoxyribonucleotides with site-specific modifications have been used as substrates for Escherichia coli DNA polymerase I holoenzyme and Klenow fragment. Modifications included the bulky guanine-8-aminofluorene adduct and a guanine oxidation product resembling the product of photosensitized DNA oxidation. By a combination of primers and nick-mers, conditions of single-strand-directed DNA synthesis and nick-translation could be created. The results show that the polymerase can bypass both types of lesions. Bypass occurs on a single-stranded template but is facilitated on a nicked, double-stranded template. Only purines, with guanine more favored than adenine, are incorporated across both lesions. The results indicate that site-specifically modified oligonucleotides can be sensitive probes for the action of polymerases on damaged templates. They also suggest a function for polymerase I, in its nick-translation capacity, during DNA repair and mutagenesis

  12. Alteration of Sequence Specificity of the Type IIS Restriction Endonuclease BtsI

    OpenAIRE

    Guan, Shengxi; Blanchard, Aine; Zhang, Penghua; Zhu, Zhenyu

    2010-01-01

    The Type IIS restriction endonuclease BtsI recognizes and digests at GCAGTG(2/0). It comprises two subunits: BtsIA and BtsIB. The BtsIB subunit contains the recognition domain, one catalytic domain for bottom strand nicking and part of the catalytic domain for the top strand nicking. BtsIA has the rest of the catalytic domain that is responsible for the DNA top strand nicking. BtsIA alone has no activity unless it mixes with BtsIB to reconstitute the BtsI activity. During characterization of ...

  13. A conserved helicase processivity factor is needed for conjugation and replication of an integrative and conjugative element.

    Directory of Open Access Journals (Sweden)

    Jacob Thomas

    Full Text Available Integrative and conjugative elements (ICEs are agents of horizontal gene transfer and have major roles in evolution and acquisition of new traits, including antibiotic resistances. ICEs are found integrated in a host chromosome and can excise and transfer to recipient bacteria via conjugation. Conjugation involves nicking of the ICE origin of transfer (oriT by the ICE-encoded relaxase and transfer of the nicked single strand of ICE DNA. For ICEBs1 of Bacillus subtilis, nicking of oriT by the ICEBs1 relaxase NicK also initiates rolling circle replication. This autonomous replication of ICEBs1 is critical for stability of the excised element in growing cells. We found a conserved and previously uncharacterized ICE gene that is required for conjugation and replication of ICEBs1. Our results indicate that this gene, helP (formerly ydcP, encodes a helicase processivity factor that enables the host-encoded helicase PcrA to unwind the double-stranded ICEBs1 DNA. HelP was required for both conjugation and replication of ICEBs1, and HelP and NicK were the only ICEBs1 proteins needed for replication from ICEBs1 oriT. Using chromatin immunoprecipitation, we measured association of HelP, NicK, PcrA, and the host-encoded single-strand DNA binding protein Ssb with ICEBs1. We found that NicK was required for association of HelP and PcrA with ICEBs1 DNA. HelP was required for association of PcrA and Ssb with ICEBs1 regions distal, but not proximal, to oriT, indicating that PcrA needs HelP to progress beyond nicked oriT and unwind ICEBs1. In vitro, HelP directly stimulated the helicase activity of the PcrA homologue UvrD. Our findings demonstrate that HelP is a helicase processivity factor needed for efficient unwinding of ICEBs1 for conjugation and replication. Homologues of HelP and PcrA-type helicases are encoded on many known and putative ICEs. We propose that these factors are essential for ICE conjugation, replication, and genetic stability.

  14. Adenosine triphosphate stimulates Aquifex aeolicus MutL endonuclease activity.

    Directory of Open Access Journals (Sweden)

    Jerome Mauris

    2009-09-01

    Full Text Available Human PMS2 (hPMS2 homologues act to nick 5' and 3' to misincorporated nucleotides during mismatch repair in organisms that lack MutH. Mn(++ was previously found to stimulate the endonuclease activity of these homologues. ATP was required for the nicking activity of hPMS2 and yPMS1, but was reported to inhibit bacterial MutL proteins from Thermus thermophilus and Aquifex aeolicus that displayed homology to hPMS2. Mutational analysis has identified the DQHA(X(2E(X(4E motif present in the C-terminus of PMS2 homologues as important for endonuclease activity.We examined the effect ATP had on the Mn(++ induced nicking of supercoiled pBR322 by full-length and mutant A. aeolicus MutL (Aae MutL proteins. Assays were single time point, enzyme titration experiments or reaction time courses. The maximum velocity for MutL nicking was determined to be 1.6+/-0.08x10(-5 s(-1 and 4.2+/-0.3x10(-5 s(-1 in the absence and presence of ATP, respectively. AMPPNP stimulated the nicking activity to a similar extent as ATP. A truncated Aae MutL protein composed of only the C-terminal 123 amino acid residues was found to nick supercoiled DNA. Furthermore, mutations in the conserved C-terminal DQHA(X(2E(X(4E and CPHGRP motifs were shown to abolish Aae MutL endonuclease activity.ATP stimulated the Mn(++ induced endonuclease activity of Aae MutL. Experiments utilizing AMPPNP implied that the stimulation did not require ATP hydrolysis. A mutation in the DQHA(X(2E(X(4E motif of Aae MutL further supported the role of this region in endonclease activity. For the first time, to our knowledge, we demonstrate that changing the histidine residue in the conserved CPHGRP motif abolishes endonucleolytic activity of a hPMS2 homologue. Finally, the C-terminal 123 amino acid residues of Aae MutL were sufficient to display Mn(++ induced nicking activity.

  15. Characterization of linear forms of the circular enterocin AS-48 obtained by limited proteolysis

    NARCIS (Netherlands)

    Montalbán-López, Manuel; Spolaore, Barbara; Pinato, Odra; Martínez-Bueno, Manuel; Valdivia, Eva; Maqueda, Mercedes; Fontana, Angelo

    2008-01-01

    AS-48 is a 70-residue circular peptide from Enterococcus faecalis with a broad antibacterial activity. Here, we produced by limited proteolysis a protein species carrying a single nicking and fragments of 55 and 38 residues. Nicked AS-48 showed a lower helicity by far-ultraviolet circular dichroism

  16. Sudha Bhattacharya Jawaharlal Nehru University New Delhi

    Indian Academy of Sciences (India)

    TSC

    Bottom strand. 1. 2. 3. G A T C. 5. 1. 3. 4. 2. *. Nicking profile of EN on the 174 bp substrate. Insertion point. Bottom strand labelled 174bp substrate. Transposon insertion point. Endonuclease nicks at three hot spots. The transposon inserts at hot spot # 3 ...

  17. Inpatient Obstetric Care at Irwin Army Community Hospital: A Study to Determine the Most Efficient Organization

    Science.gov (United States)

    2001-03-01

    Reese’s new birthing suites may curb maternity malpractice suits. Modern Healthcare, 16 (11), 48. Clark, L., & Stewart, R. (1982). Nurse-midwifery...Davis Highway, Suite 1204, Arlington VA 22202-4302. Respondents should be aware that notwithstanding any other provision of law , no person shall be...US Army Medical Department Center and School Bldg 2841 MCCS-HRA (US Army-Baylor Program in HCA) 3151 Scott Road, Suite 1412 Fort Sam Houston, TX 78234

  18. Preparing General Purpose Forces in the United States and British Armies for Counterinsurgent Operations

    Science.gov (United States)

    2010-12-10

    Operations In Iraq: Planning, Combat, And Occupation,” Thomas Ricks’ Fiasco, and reports by Army historian Major Isaiah Wilson, and former CENCTOM J-4...established Multi-National Forces-Iraq, and Lieutenant General Thomas Metz, commander of the Army’s III Corps, assumed the mantle of Multi-National Corps...Donald P. Wright and Colonel Timothy R. Reese or Thomas Ricks’ Fiasco among other books. 18Dr. Carter Malkasian, “Counterinsurgency in Iraq: May 2003

  19. Tension Tests On Bored Piles In Sand

    DEFF Research Database (Denmark)

    Krabbenhøft, Sven; Clausen, Johan; Damkilde, Lars

    2006-01-01

    The lengths of the bored piles varied from 2 m to 6 m and all were of a diameter of 140 mm. The piles were tested to failure in tension and the load-displacement relations were recorded. The investigation has shown pronounced differences between the load bearing capacities obtained by different...... design methods. The methods proposed by Fleming et al. and Reese & O’Neill seem to produce the best match with the test results....

  20. Structure-guided mutational analysis of the OB, HhH, and BRCT domains of Escherichia coli DNA ligase.

    Science.gov (United States)

    Wang, Li Kai; Nair, Pravin A; Shuman, Stewart

    2008-08-22

    NAD(+)-dependent DNA ligases (LigAs) are ubiquitous in bacteria and essential for growth. LigA enzymes have a modular structure in which a central catalytic core composed of nucleotidyltransferase and oligonucleotide-binding (OB) domains is linked via a tetracysteine zinc finger to distal helix-hairpin-helix (HhH) and BRCT (BRCA1-like C-terminal) domains. The OB and HhH domains contribute prominently to the protein clamp formed by LigA around nicked duplex DNA. Here we conducted a structure-function analysis of the OB and HhH domains of Escherichia coli LigA by alanine scanning and conservative substitutions, entailing 43 mutations at 22 amino acids. We thereby identified essential functional groups in the OB domain that engage the DNA phosphodiester backbone flanking the nick (Arg(333)); penetrate the minor grove and distort the nick (Val(383) and Ile(384)); or stabilize the OB fold (Arg(379)). The essential constituents of the HhH domain include: four glycines (Gly(455), Gly(489), Gly(521), Gly(553)), which bind the phosphate backbone across the minor groove at the outer margins of the LigA-DNA interface; Arg(487), which penetrates the minor groove at the outer margin on the 3 (R)-OH side of the nick; and Arg(446), which promotes protein clamp formation via contacts to the nucleotidyltransferase domain. We find that the BRCT domain is required in its entirety for effective nick sealing and AMP-dependent supercoil relaxation.

  1. 78 FR 12294 - Proposed Information Collection; Comment Request; Defense Priorities and Allocations System

    Science.gov (United States)

    2013-02-22

    ...: Direct all written comments to Jennifer Jessup, Departmental Paperwork Clearance Officer, Department of...) 482-4895, Lawrence[email protected] . SUPPLEMENTARY INFORMATION: I. Abstract This recordkeeping...

  2. 78 FR 22512 - Proposed Information Collection; Comment Request; Special Priorities Assistance

    Science.gov (United States)

    2013-04-16

    ... written comments to Jennifer Jessup, Departmental Paperwork Clearance Officer, Department of Commerce...) 482-4895, Lawrence[email protected] . SUPPLEMENTARY INFORMATION: I. Abstract The information collected...

  3. Palju alusetuid lubadusi / Erik Morna

    Index Scriptorium Estoniae

    Morna, Erik, 1969-

    1999-01-01

    Heliplaatidest : Stina Nordenstam : People are strange ; Mariah Carey : 1'S ; Muusika filmist ja filmist inspireeritud muusika : Psycho ; Erinevad gershwinistid : Red Hot + Rhapsody ; Jennifer Rush : Classics

  4. 77 FR 1915 - Proposed Information Collection; Comment Request; Licensing Responsibilities and Enforcement

    Science.gov (United States)

    2012-01-12

    ...: Direct all written comments to Jennifer Jessup, Departmental Paperwork Clearance Officer, Department of...) 482-4895, Lawrence[email protected] . SUPPLEMENTARY INFORMATION: I. Abstract This collection of...

  5. 78 FR 48138 - Proposed Information Collection; Comment Request; Report of Requests for Restrictive Trade...

    Science.gov (United States)

    2013-08-07

    ..., 2013. ADDRESSES: Direct all written comments to Jennifer Jessup, Departmental Paperwork Clearance... Hall, BIS ICB Liaison, (202) 482-4895, Lawrence[email protected] . SUPPLEMENTARY INFORMATION: I...

  6. 77 FR 54559 - Proposed Information Collection; Comment Request; Offsets in Military Exports

    Science.gov (United States)

    2012-09-05

    ...: Direct all written comments to Jennifer Jessup, Departmental Paperwork Clearance Officer, Department of...) 482-4895, Lawrence[email protected] . SUPPLEMENTARY INFORMATION: I. Abstract This collection of...

  7. Pop / Mart Niineste

    Index Scriptorium Estoniae

    Niineste, Mart, 1983-

    2005-01-01

    Heliplaatidest: Slide Fifty "The Way Ahead", Idlewild "Warnings/Promises", Electric Six "Senor Smoke", Erinevad esitajad "Playboy: The Mansion Soundtrack Mixed by Felix da Housecat", Jennifer Lopez "Rebirth"

  8. 78 FR 32245 - Notice of Receipt of Pesticide Products; Registration Applications To Register New Uses

    Science.gov (United States)

    2013-05-29

    ... Road, Pasadena, TX 77507-1041. Active ingredient: Novaluron. Product Type: Insecticide; Insect Growth... furniture, animal quarters, carpets, kennels, and poultry houses. Contact: Jennifer Gaines, (703) 305-5967...

  9. 76 FR 78672 - National Institute on Drug Abuse; Notice of Closed Meeting

    Science.gov (United States)

    2011-12-19

    ..., Neuroscience Center, 6001 Executive Boulevard, Rockville, MD 20852 (Telephone Conference Call). Contact Person... Addiction Research Programs, National Institutes of Health, HHS) Dated: December 13, 2011. Jennifer S...

  10. 77 FR 36479 - Proposed Information Collection; Comment Request; License Transfer and Duplicate License Services

    Science.gov (United States)

    2012-06-19

    ...: Direct all written comments to Jennifer Jessup, Departmental Paperwork Clearance Officer, Department of...) 482-4895, Lawrence[email protected] . SUPPLEMENTARY INFORMATION: I. Abstract This collection is needed...

  11. 78 FR 56859 - Proposed Information Collection; Comment Request; Triangular Transactions Covered by a U.S...

    Science.gov (United States)

    2013-09-16

    ... 15, 2013. ADDRESSES: Direct all written comments to Jennifer Jessup, Departmental Paperwork Clearance... Hall, BIS ICB Liaison, (202) 482-4895, Lawrence[email protected] . SUPPLEMENTARY INFORMATION: I...

  12. Enzyme-linked electrochemical DNA ligation assay using magnetic beads.

    Science.gov (United States)

    Stejskalová, Eva; Horáková, Petra; Vacek, Jan; Bowater, Richard P; Fojta, Miroslav

    2014-07-01

    DNA ligases are essential enzymes in all cells and have been proposed as targets for novel antibiotics. Efficient DNA ligase activity assays are thus required for applications in biomedical research. Here we present an enzyme-linked electrochemical assay based on two terminally tagged probes forming a nicked junction upon hybridization with a template DNA. Nicked DNA bearing a 5' biotin tag is immobilized on the surface of streptavidin-coated magnetic beads, and ligated product is detected via a 3' digoxigenin tag recognized by monoclonal antibody-alkaline phosphatase conjugate. Enzymatic conversion of napht-1-yl phosphate to napht-1-ol enables sensitive detection of the voltammetric signal on a pyrolytic graphite electrode. The technique was tested under optimal conditions and various situations limiting or precluding the ligation reaction (such as DNA substrates lacking 5'-phosphate or containing a base mismatch at the nick junction, or application of incompatible cofactor), and utilized for the analysis of the nick-joining activity of a range of recombinant Escherichia coli DNA ligase constructs. The novel technique provides a fast, versatile, specific, and sensitive electrochemical assay of DNA ligase activity.

  13. Staarid, kellel on oma parfüüm

    Index Scriptorium Estoniae

    2006-01-01

    Parfüümidest: Britney Spearsi "Fantasy, Paris Hiltoni "Just Me", Maria Sharapova "Maria Sharapova", Sarah Jessica Parkeri "Lovely", Jennifer Lopezi "Still", David ja Viktoria Beckhami "Intimately Beckham"

  14. 75 FR 3912 - Center for Scientific Review; Notice of Closed Meeting

    Science.gov (United States)

    2010-01-25

    ... (Telephone Conference Call). Contact Person: Lawrence Baizer, PhD, Scientific Review Officer, Center for... Health, HHS) Dated: January 15, 2010. Jennifer Spaeth, Director, Office of Federal Advisory Committee...

  15. Sõbrad - kõmuliselt edukad ja edukalt kõmulised / Elo Mõttus

    Index Scriptorium Estoniae

    Mõttus, Elo

    2001-01-01

    Ameerika Ühendriikide edukast komöödiasarjast "Sõbrad" ("Friends") ja selle peategelaste kehastajatest (Matthew Perry, Jennifer Aniston, David Schwimmer,Courtney Cox). Ka : Teleleht nr. 18, lk. 42

  16. Modeli i pevitsõ v vashem shkafu / Alina Zelimhanova

    Index Scriptorium Estoniae

    Zelimhanova, Alina

    2003-01-01

    Tuntud modellide ja lauljate tegevusest moedisineritena. Modell Anouck Lepere disainib kõrvarõngaid, Stella Tennant lasterõivaid, lauljad Jennifer Lopez, Britney Spears ja Kylie Minogue on moekollektsioonide autorid

  17. "Who's There?": Shakespeare and the Dragon of Autism

    Science.gov (United States)

    Renino, Christopher

    2009-01-01

    Dan recently turned 13; Nick will soon be 12. Both boys are smart and fun; both are loving, write like angels, like to learn, and want friends; both are autistic and hope to learn to speak. They find it challenging to relate to and function in this world, and they work hard to improve their abilities to do so. Last fall, Nick and Dan became…

  18. 75 FR 54159 - National Institute on Aging; Notice of Closed Meetings

    Science.gov (United States)

    2010-09-03

    ...: National Institute on Aging Special Emphasis Panel, Stem Cells and Genomic Integrity Through Senescense.... 93.866, Aging Research, National Institutes of Health, HHS) Dated: August 26, 2010. Jennifer S...

  19. INTEGRATIVE APPROACH ON FRAMING THEORY FROM ITS MULTIPARADIGMATIC CONDITION

    OpenAIRE

    Marín Albaladejo, Juan Antonio; Zamora Medina, Rocío

    2014-01-01

    La Teoría del framing ha alcanzado un creciente protagonismo en la investigación en Comunicación que incluye postulados comunes entre diferentes perspectivas de investigación. A la multiplicidad de formas de entender el concepto de frame, se une la controversia sobre los tipos de encuadres que existen. A pesar de los numerosos esfuerzos integradores (D’Angelo, 2002; De Vreese, 2005; Entman, 1993, 2004; López-Rabadán, 2010; Matthes, 2012; Reese, 2007; Scheufele, 1999), no se ha alcanzado todav...

  20. The structuring considerations of a Ricoeurian hermeneutic employed in a reading of Proverbs 14:2

    Directory of Open Access Journals (Sweden)

    Anneke Viljoen

    2015-06-01

    Full Text Available A Ricoeurian hermeneutic affords readers of the Old Testament an opportunity to access the biblical text anew as a source and norm for faith. Reese gave a convenient summarising description of Ricoeur’s hermeneutical approach. Ricoeur organised his considerations around four poles, namely distanciation, objectification, projecting of a world, and appropriation. These operate as the structuring considerations of a Ricoeurian hermeneutic and were illustrated with a sample proverb (i.e. Pr 14:2 from the collection Proverbs 10:1–15:33.

  1. Plaadid / Mirjam Tally

    Index Scriptorium Estoniae

    Tally, Mirjam, 1976-

    2003-01-01

    Uutest plaatidest "Mirjam Tally", Jennifer Love Hewitt "Barenaked", Sam "Being Under The Influence", Slade "Cum On Let's Party", The Dandy Warhols "Welcome To The Monkey House", Audio Bullys "Ego War"

  2. 78 FR 41032 - Proposed Information Collection; Comment Request; Foreign Availability Procedures

    Science.gov (United States)

    2013-07-09

    ... comments to Jennifer Jessup, Departmental Paperwork Clearance Officer, Department of Commerce, Room 6616... instrument and instructions should be directed to Larry Hall, BIS ICB Liaison, (202) 482-4895, Lawrence.Hall...

  3. 76 FR 7225 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-02-09

    ... Mark Hopkins Hotel, 999 California Street, San Francisco, CA 94108. Contact Person: Lawrence E Boerboom..., National Institutes of Health, HHS) Dated: February 3, 2011. Jennifer S. Spaeth, Director, Office of...

  4. Plaadid / Andri Maimets

    Index Scriptorium Estoniae

    Maimets, Andri, 1979-

    2005-01-01

    Uutest heliplaatidest Jennifer Lopez "Rebirth", Crosby Stills & Nash "Greatest Hits", "Verve/Remixe", Thirteen Senses "The Invitation", "Amos Lee", Mari Boine "Gula Gula", dZihan & Kamien "Fakes", Hot Hot Heat "Elevator"

  5. The preparation of radioactivity labelled DNA

    International Nuclear Information System (INIS)

    Ballance, P.; Morgan, J.; McGregor, G.; Durkacz, B.

    1984-01-01

    The nick translation reaction, which uses the endonuclease enzyme to incorporate pieces of DNA into the genetic material of other organisms, is being used more and more in Molecular Biology research for the preparation of pure DNA labelled with 32 P. However results are presented which show that high radiation doses are received by the hands of nick translation workers. A Scheme of Work to reduce these doses is described. (author)

  6. Use of Performance Measures to Evaluate, Document Competence and Deterioration of ASSET Surgical Skills

    Science.gov (United States)

    2016-05-01

    meeting with Advisory Board Member, Prof Nick Sevdalis (London UK) in Seattle at the ASE meeting (April 21-25 2015) to address how to validate our...cognitive task analysis and human factors, and Prof. Nick Sevdalis , an experimental psychologist and expert in patient safety in hospital...Individual Procedure Score (IPS) performance metric and to update Prof Sevdalis on project progress.  Presented a poster and 2 podium presentation at

  7. African Journal of Reproductive Health - Vol 20, No 2 (2016)

    African Journals Online (AJOL)

    John K. Ganle, Bernard Obeng, Joseph Y. Yeboah, Eva Tagoe-Darko, ... Christine Chingondole, Virginia Chipangula, Mina C. Hosseinipour, Jennifer H. ... Esperanza Mariano, Francisco Mbofana, Terence Hull, Adriane Martin Hilber, 111-121.

  8. 75 FR 42449 - National Cancer Institute; Notice of Meeting

    Science.gov (United States)

    2010-07-21

    ... Translational Research Advisory Committee. The meeting will be open to the public, with attendance limited to... Health, HHS) Dated: July 15, 2010. Jennifer Spaeth, Director, Office of Federal Advisory Committee Policy...

  9. Cross-genus amplification and characterisation of microsatellite loci ...

    African Journals Online (AJOL)

    Cross-genus amplification and characterisation of microsatellite loci in the little free tailed bat, Chaerephon pumilus s. l. (Molossidae) from South Eastern Africa. Theshnie Naidoo, Angus Macdonald, Jennifer M Lamb ...

  10. 76 FR 22111 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-04-20

    ..., MD 20892. (Telephone Conference Call.) Contact Person: Lawrence Ka-Yun Ng, PhD, Scientific Review... Institutes of Health, HHS) Dated: April 12, 2011. Jennifer S. Spaeth, Director, Office of Federal Advisory...

  11. 78 FR 41032 - Proposed Information Collection; Comment Request; Special Comprehensive License

    Science.gov (United States)

    2013-07-09

    ... to Jennifer Jessup, Departmental Paperwork Clearance Officer, Department of Commerce, Room 6616, 14th... instrument and instructions should be directed to Larry Hall, BIS ICB Liaison, (202) 482-4895, Lawrence.Hall...

  12. 76 FR 10912 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-02-28

    ... 22202. Contact Person: Lawrence E Boerboom, PhD, Scientific Review Officer, Center for Scientific Review... Institutes of Health, HHS) Dated: February 18, 2011. Jennifer S. Spaeth, Director, Office of Federal Advisory...

  13. 76 FR 47218 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-08-04

    ..., Bethesda, MD 20892, (Telephone Conference Call). Contact Person: Lawrence Ka-Yun Ng, PhD, Scientific Review..., HHS) Dated: July 28, 2011. Jennifer S. Spaeth, Director, Office of Federal Advisory Committee Policy...

  14. San Francisco Littoral Cell CRSMP Coastal Armoring Lines 2011

    Data.gov (United States)

    California Natural Resource Agency — This dataset is an updated version of the shapefile created by Jennifer Dare at the California Coastal Commission in 2005. The version created by Elena Vandebroek...

  15. San Francisco Littoral Cell CRSMP Coastal Armoring Areas 2011

    Data.gov (United States)

    California Natural Resource Agency — This dataset is an updated version of the shapefile created by Jennifer Dare at the California Coastal Commission in 2005. The version created by Elena Vandebroek...

  16. San Francisco Littoral Cell CRSMP Coastal Armoring Areas 2011

    Data.gov (United States)

    California Department of Resources — This dataset is an updated version of the shapefile created by Jennifer Dare at the California Coastal Commission in 2005. The version created by Elena Vandebroek...

  17. San Francisco Littoral Cell CRSMP Coastal Armoring Lines 2011

    Data.gov (United States)

    California Department of Resources — This dataset is an updated version of the shapefile created by Jennifer Dare at the California Coastal Commission in 2005. The version created by Elena Vandebroek...

  18. Why is John More Likely to Become Department Chair Than Jennifer?

    Science.gov (United States)

    Carnes, Molly; Bartels, Christie M.; Kaatz, Anna; Kolehmainen, Christine

    2015-01-01

    This article reviews some of our research on how gender stereotypes and their accompanying assumptions and expectations can influence the careers of male and female physicians and scientists in a myriad of subtle ways. Although stereotype-based cognitive biases may be invisible and unintentional, they nevertheless shape the experiences of women in academic medicine in ways that frequently constrain their opportunities. We present research on the following: 1) subtle differences in the evaluation of male and female medical students as revealed through text analysis of written evaluations at a critical career juncture, 2) how cultural assumptions about the way men and women should and should not behave influence medical residents' experiences as leaders, and 3) how approaching gender bias among faculty in academic medicine, science, and engineering as a remedial habit can be successful in changing individual behaviors and in improving department climate. PMID:26330674

  19. Profiling and understanding student information behaviour: methodologies and meaning Jennifer Rowley

    Directory of Open Access Journals (Sweden)

    Jennifer Rowley

    2003-12-01

    Full Text Available This paper draws on work conducted under the Joint Information Systems Committee (JISC User Behaviour Monitoring and Evaluation Framework to identify a range of issues associated with research design that can form a platform for enquiry about knowledge creation in the arena of user behaviour. The Framework has developed a multidimensional set of tools for profiling, monitoring and evaluating user behaviour. The Framework has two main approaches: one, a broad-based survey which generates both a qualitative and a quantitative profile of user behaviour, and the other a longitudinal qualitative study of user behaviour that (in addition to providing in-depth insights is the basis for the development of the EIS (Electronic Information Services Diagnostic Toolkit. The strengths and weaknesses of the Framework approach are evaluated. In the context of profiling user behaviour, key methodological concerns relate to: representativeness, sampling and access, the selection of appropriate measures and the interpretation of those measures. Qualitative approaches are used to generate detailed insights. These include detailed narratives, case study analysis and gap analysis. The messages from this qualitative analysis do not lend themselves to simple summarization. One approach that has been employed to capture and interpret these messages is the development of the EIS Diagnostic Toolkit. This toolkit can be used to assess and monitor an institution's progress with embedding EIS into learning processes. Finally, consideration must be given to integration of insights generated through different strands within the Framework.

  20. Why is John More Likely to Become Department Chair Than Jennifer?

    Science.gov (United States)

    Carnes, Molly; Bartels, Christie M; Kaatz, Anna; Kolehmainen, Christine

    2015-01-01

    This article reviews some of our research on how gender stereotypes and their accompanying assumptions and expectations can influence the careers of male and female physicians and scientists in a myriad of subtle ways. Although stereotype-based cognitive biases may be invisible and unintentional, they nevertheless shape the experiences of women in academic medicine in ways that frequently constrain their opportunities. We present research on the following: 1) subtle differences in the evaluation of male and female medical students as revealed through text analysis of written evaluations at a critical career juncture, 2) how cultural assumptions about the way men and women should and should not behave influence medical residents' experiences as leaders, and 3) how approaching gender bias among faculty in academic medicine, science, and engineering as a remedial habit can be successful in changing individual behaviors and in improving department climate.

  1. CrossTalk: The Journal of Defense Software Engineering. Volume 20, Number 11, November 2007

    National Research Council Canada - National Science Library

    2007-01-01

    ...: Partnership for Project Success." Jennifer Tucker and Hile Rutledge describe the necessity of maximizing team performance in "Shaping Motivation and Emotion in Technology Teams," and Kasey Thompson and Tim Border teach managers...

  2. 76 FR 20359 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-04-12

    ..., Bethesda, MD 20892 (Telephone Conference Call). Contact Person: Lawrence E Boerboom, PhD, Chief, CVRS IRG...: April 4, 2011. Jennifer S. Spaeth, Director, Office of Federal Advisory Committee Policy. [FR Doc. 2011...

  3. 77 FR 2270 - Proposed Information Collection; Comment Request; Firearms Convention

    Science.gov (United States)

    2012-01-17

    ... Jennifer Jessup, Departmental Paperwork Clearance Officer, Department of Commerce, Room 6616, 14th and... and instructions should be directed to Larry Hall, BIS ICB Liaison, (202) 482-4895, Lawrence[email protected

  4. 75 FR 28853 - Quarterly Publication of Individuals, Who Have Chosen To Expatriate, as Required by Section 6039G

    Science.gov (United States)

    2010-05-24

    ... CURLEY RENATE H DARD GILLES DE TREY LORRAINE ANNE DECKER MARGARET DEUCHER FIONA CLARINA DEUCHER ANNINA... JENNIFER LADANYI HANS GEORG LAMPE ARNO LAUREYNS VEERLE A LEBECH LISA MARGARET LEE YOONBOK STEPHEN LEHMANN...

  5. Landscapes of The Mind: The Setting as Psyche in Nathaniel Hawthorne's The Scarlet Letter And F. Scott Fitzgerald's The Great Gatsby Landscapes of The Mind: The Setting as Psyche in Nathaniel Hawthorne's The Scarlet Letter And F. Scott Fitzgerald's The Great Gatsby

    Directory of Open Access Journals (Sweden)

    Cruce Stark

    2009-09-01

    Full Text Available In the closing moment of F. Scott Fitzgerald's The Great Gateby, Nick returns for one last look at what once was Gateby's house. But instead of physical buildings, he has a vision of an earlier time, a vision of the "old island" that "flowered once for Dutch sailor's eyes -- a fresh green breast of the new world." "For a transitory enchanted moment," Nick thinks, "man must have held his breath in the presence of this continent, compelled into an aesthetic contemplation he neither understood nor desired, face to face for the last time in history with something commensurate to his capacity for wonder (182." In the closing moment of F. Scott Fitzgerald's The Great Gateby, Nick returns for one last look at what once was Gateby's house. But instead of physical buildings, he has a vision of an earlier time, a vision of the "old island" that "flowered once for Dutch sailor's eyes -- a fresh green breast of the new world." "For a transitory enchanted moment," Nick thinks, "man must have held his breath in the presence of this continent, compelled into an aesthetic contemplation he neither understood nor desired, face to face for the last time in history with something commensurate to his capacity for wonder (182."

  6. A view from the top: US enrichment Corp.'s William H. Timbers, Jr

    International Nuclear Information System (INIS)

    Giltenan, E.

    1993-01-01

    Nick Timbers took over as the first Transition Manager of the US Enrichment Corporation upon its founding last July 1st. Although USEC is not involved in negotiating the HEU deal, the fledgling company will be in charge of actually buying and selling the resulting LEU. Whenever the deal is finally signed. After the politics and haggling are over, it will be up to Nick Timbers to make the deal work on the global uranium market. The view from USEC is resolute. No matter what shape the final HEU deal takes, Nick Timbers promises that USEC will remain a competitive supplier of enrichment services. Timbers pledges that any extra costs associated with the HEU deal will not be passed on to customers. He took time out from his recent busy schedule to share his thoughts on HEU and its aftermath

  7. Crossing the street

    DEFF Research Database (Denmark)

    Shepherd, Nick

    2001-01-01

    Nick Shepherd teaches a class on 'race and racism' at the University of Cape Town. Here he shares the journey he undertakes with his students to find a "civil space'' to discuss sensitive and complex issues.......Nick Shepherd teaches a class on 'race and racism' at the University of Cape Town. Here he shares the journey he undertakes with his students to find a "civil space'' to discuss sensitive and complex issues....

  8. YIP Expansion: Ocean Basin Impact of Ambient Noise on Marine Mammal Detectability, Distribution, and Acoustic Communication

    Science.gov (United States)

    2015-09-30

    Marine Mammal Detectability, Distribution, and Acoustic Communication Jennifer L. Miksis-Olds Applied Research Laboratory The Pennsylvania State...relatively stereotyped calls, commonly considered types of automatic detection include spectrogram correlation and matched filtering. Spectrogram

  9. 77 FR 12561 - Antidumping or Countervailing Duty Order, Finding, or Suspended Investigation; Advance...

    Science.gov (United States)

    2012-03-01

    ... Department contact Folding Gift Boxes From the People's Republic Jennifer Moats (202) 482-5047. of China (A... analytical issues relevant to the Department's conduct of Sunset Reviews is set forth in the Department's...

  10. Preventing Pneumonia (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    Pneumonia is a lung infection that can result in severe illness and even death. Common symptoms include cough, fever, and difficulty breathing. In this podcast, Dr. Jennifer Farrar discusses ways to prevent pneumonia.

  11. 77 FR 9675 - Center for Scientific Review: Notice of Closed Meetings

    Science.gov (United States)

    2012-02-17

    ... Wisconsin Avenue, Bethesda, MD 20814. Contact Person: Lawrence E Boerboom, Ph.D., Chief, CVRS IRG, Center...-93.878, 93.892, 93.893, National Institutes of Health, HHS) Dated: February 10, 2012. Jennifer S...

  12. 76 FR 63312 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-10-12

    ...: Lawrence E Boerboom, PhD, Chief, CVRS IRG, Center for Scientific Review, National Institutes of Health.... Jennifer S. Spaeth, Director, Office of Federal Advisory Committee Policy. [FR Doc. 2011-26355 Filed 10-11...

  13. Letter re: Bio - Lab, Plants 2 and 4, Conyers, Rockdale County

    Science.gov (United States)

    September 24, 1999 letter to Jeffrey T. Pallas from Jennifer R. Kaduck enclosing information about conditionally exempt small quantity generator requirements for Bio - Lab Plants 2 and 4 in Conyers, Rockdale County, Georgia.

  14. South African Medical Journal - Vol 96, No 6 (2006)

    African Journals Online (AJOL)

    Tuberculosis control in South Africa – will HAART help? ... Jennifer A Thomson, 509-510 ... Masking through averages - intraprovincial heterogeneity in HIV prevalence within the Western Cape · EMAIL FREE FULL TEXT EMAIL FREE FULL ...

  15. Physiological and molecular insights into drought tolerance ...

    African Journals Online (AJOL)

    Physiological and molecular insights into drought tolerance. Sagadevan G Mundree, Bienyameen Baker, Shaheen Mowla, Shaun Peters, Saberi Marais, Clare Vander Willigen, Kershini Govender, Alice Maredza, Samson Muyanga, Jill M Farrant, Jennifer A Thomson ...

  16. Naise võim Bermudas : kubjas kukutati / Allan Espenberg

    Index Scriptorium Estoniae

    Espenberg, Allan

    2003-01-01

    Suurbritanniale kuuluva Bermuda saare parlamendivalimised vallandasid sündmuste ahela, mis võivad muuta asumaa poliitikat. Ametist tagandati peaminister Jennifer Meredith Smith ja uueks peaministriks sai senine tööminister William Alexander Scott

  17. Prevalence and Severity of Dental Fluorosis in the United States, 1999-2004

    Science.gov (United States)

    ... Surveys. References Aoba T, Fejerskov O. Dental fluorosis: Chemistry and biology. Crit Rev Oral Biol Med 13( ... National Center for Health Statistics Edward J. Sondik, Ph.D., Director Jennifer H. Madans, Ph.D., Associate ...

  18. Greens protest at U. S. Embassy / Nick Coleman

    Index Scriptorium Estoniae

    Coleman, Nick

    2000-01-01

    Protestijad kogunesid USA Riia saatkonna hoone ette. Väljendati oma rahulolematust USA tahtmatuse suhtes vähendada süsinikdioksüüdi paiskamist õhkkonda, mis ilmnes eelmisel kuul peetud kliimamuutuse konverentsil Haagis

  19. Oscarite gala pole enam miljoni valge mehe marss / Triin Tael

    Index Scriptorium Estoniae

    Tael, Triin

    2007-01-01

    79. Oscarite gala oli Martin Scorsese maffiadraama "Kahe tule vahel" ja mustanahaliste näitlejate triumf. Parimaks meesnäitlejaks kuulutati Forest Whitaker ja parimaks naiskõrvalosatäitjaks Jennifer Hudson. Ka varasematest võitjatest

  20. 77 FR 19623 - Antidumping or Countervailing Duty Order, Finding, or Suspended Investigation; Advance...

    Science.gov (United States)

    2012-04-02

    ... contact Polyester Staple Fiber from the Jennifer Moats, (202) 482-5047. People's Republic of China (A-570... Reviews are set forth in 19 CFR 351.218. Guidance on methodological or analytical issues relevant to the...

  1. 76 FR 39245 - Energy Conservation Program: Energy Conservation Standards for Residential Furnaces and...

    Science.gov (United States)

    2011-07-06

    ... Wes.Anderson@ee.doe.gov . Mr. Eric Stas or Ms. Jennifer Tiedeman, U.S. Department of Energy, Office of.... Wesley Anderson (central air conditioners and heat pumps), U.S. Department of Energy, Office of Energy...

  2. Book Review of 'The Metropolitan Revolution, How Cities and Metros are fixing our Broken Policies and Fragile Economy'

    OpenAIRE

    Fitzpatrick, Miriam

    2014-01-01

    Book Reviews for Architecture Ireland of 'The Metropolitan Revolution, How Cities and Metros are fixing our Broken Policies and Fragile Economy', by Bruce Katz and Jennifer Bradley, Published by Brookings Institution Press, 288 pages.

  3. Review Article: The Vanished Ghosts in Two Hungarian Family Memoirs. Farkas, Charles. 2013. Vanished by the Danube: Peace, War, Revolution, and Flight to the West (Introduction by Margaret McMullan. Albany: Excelsior Editions, State University of New York Press. 472 pp. Illus; and Barlay, Nick. 2013. Scattered Ghosts: One Family's Survival through War, Holocaust and Revolution. London and New York: I. B. Tauris. 240 pp. Illus.

    Directory of Open Access Journals (Sweden)

    Ruth G. Biro

    2015-01-01

    Full Text Available Recent personal documentary works about major historical events of the twentieth century, e.g., World War II, the Holocaust and the 1956 Hungarian Revolution, offer their readers a rich and multifaceted narrative, or a history that is also "his story," "her story" and that of entire families, cohorts and communities. Often, these works are accompanied by visual artifacts such as photographs, family tress, maps etc., or supported by concise historical surveys. Thus these memoirs complete the work of historians with the lived experiences of the few that represent many. Such is the case with two 2013 books by Charles Farkas and Nick Barlay depicting their mid-twentieth century Hungarian families, one Christian and one Jewish, through two World Wars and the anti-communist uprising, culminating in their escape to the West and in the two authors looking back upon the Hungarian past of their families.

  4. Pain Management (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    Arthritis is one of the most common chronic conditions in the United States. Unfortunately, as the population ages, it's only expected to increase. In this podcast, Dr. Jennifer Hootman discusses ways to manage the pain of arthritis.

  5. Browse Title Index

    African Journals Online (AJOL)

    Items 51 - 100 of 163 ... H Rüther, C Held, R Bhurtha, R Schroeder, S Wessels ... Richard Fiifi Annan, Yao Yevenyo Ziggah, John Ayer, Christian Amans Odutola ... Simon Hull, Tshepiso Sehume, Sibonakaliso Sibiya, Lusanda Sothafile, Jennifer ...

  6. What Is Dry Eye?

    Medline Plus

    Full Text Available ... removed or pushed down the tear duct to insert a permanent punctal plug? Sep 12, 2017 Why ... Eye from Jennifer Aniston Sep 02, 2016 The link between seasonal allergens and dry eye Apr 27, ...

  7. 78 FR 46575 - Antidumping or Countervailing Duty Order, Finding, or Suspended Investigation; Advance...

    Science.gov (United States)

    2013-08-01

    ... from China (A-570- 919) (1st Review). Steel Wire Garment Hangers Jennifer Moats (202) 482-5047. from... receives a Notice of Intent to Participate from a member of the domestic industry within 15 days of the...

  8. Lack of evidence that the XqYq pairing tips at meiosis in the mouse show hypersensitivity to DNAse I.

    Science.gov (United States)

    Separovic, E R; Chandley, A C

    1987-01-01

    In situ nick translation procedures have been applied to meiotic metaphase I divisions of the normal and XY, Sxr mouse. Unlike in man, where the pairing tips of the XY bivalent show a special sensitivity to DNAse I nicking, no such sensitivity can be detected for either of these types of mouse. Hypersensitivity in the D-band equivalent region of the X chromosome does, however, exist, this site being early replicating in somatic cells and housing the X inactivation centre (Xce).

  9. Substrate specificity of Micrococcus luteus uv endonuclease and its overlap with DNA photolyase activity

    International Nuclear Information System (INIS)

    Patrick, M.H.

    1975-01-01

    The action of an endonuclease from Micrococcus luteus that operates on uv damage in DNA overlaps with that of DNA photolyase from yeast: homo- and heterocyclobutane dipyrimidines in DNA are substrates for both enzymes, but pyrimidine adducts or the spore photoproduct in DNA are not. As expected from this overlap, the action of the two enzymes is mutually interfering: single-strand nicks introduced by the endonuclease effectively preclude photoreactivation; conversely, formation of a photolyase-cyclobutane dipyrimidine complex can prevent nicking by the endonuclease

  10. Hatten af for Cohens skønheder og skyggesider

    DEFF Research Database (Denmark)

    Mortensen, Lise Majgaard

    2011-01-01

    Der er højt til loftet i Aarhus Teaters nye teaterkoncert, som behandler selveste Leonard Cohens lyriske univers. Det er svært at lade være med at sammenligne forestillingen her med Nick Cave Teaterkoncerten, der gik sin sejrsgang i 2007 og 2008. Men det skal man ikke. Instruktøren er den samme....... Men hvor ’Nick Cave’ var rå, grim, provokerende og uanstændig, er ’Leonard Cohen’ en skrøbelig gentleman med en skyggeside....

  11. Spinal Cord Injury 101

    Medline Plus

    Full Text Available ... Counseling Blog About Media Donate Spinal Cord Injury Medical Expert Videos Topics menu Topics Spinal Cord Injury ... Jennifer Piatt, PhD David Chen, MD Read Bio Medical Director, Spinal Cord Injury Rehabilitation Program, Rehabilitation Institute ...

  12. text22.html | chandajog | 73am talks | annmeet | meetings | Indian ...

    Indian Academy of Sciences (India)

    ACADEMY PUBLIC LECTURE: Animal Sex Determination by Genes, Chromosomes and Environment. Posted on 12th March 2018. SPEAKER: Prof. Jennifer A Marshal Graves. VENUE: Faculty Hall, Indian Institute of Science. 13 March 2018 ǀ 1600. Event poster ...

  13. Basics of SCI Rehabilitation

    Medline Plus

    Full Text Available ... RN Pediatric Injuries Pediatric Spinal Cord Injury 101 Lawrence Vogel, MD The Basics of Pediatric SCI Rehabilitation ... Rogers, PT Recreational Therapy after Spinal Cord Injury Jennifer Piatt, PhD Kristine Cichowski, MS Read Bio Founding ...

  14. Sex and Fertility After SCI

    Medline Plus

    Full Text Available ... RN Pediatric Injuries Pediatric Spinal Cord Injury 101 Lawrence Vogel, MD The Basics of Pediatric SCI Rehabilitation ... Rogers, PT Recreational Therapy after Spinal Cord Injury Jennifer Piatt, PhD Diane M. Rowles, MS, NP Read ...

  15. Spinal Cord Injury 101

    Medline Plus

    Full Text Available ... RN Pediatric Injuries Pediatric Spinal Cord Injury 101 Lawrence Vogel, MD The Basics of Pediatric SCI Rehabilitation ... Rogers, PT Recreational Therapy after Spinal Cord Injury Jennifer Piatt, PhD David Chen, MD Read Bio Medical ...

  16. 76 FR 25308 - Marine Mammals

    Science.gov (United States)

    2011-05-04

    ...-XA165 Marine Mammals AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric... Jennifer Burns, Ph.D., University of Alaska Anchorage, Biology Department, 3101 Science Circle, Anchorage, AK, has been issued a permit to conduct [[Page 25309

  17. Preliminary study of the favorability for uranium in selected areas in the Basin and Range Province, Nevada

    International Nuclear Information System (INIS)

    Cupp, G.M.; Leedom, S.H.; Mitchell, T.P.; Kiloh, K.D.; Horton, R.C.

    1977-10-01

    Six uranium areas in Nevada were examined in a reconnaissance fashion to determine their favorability for uranium deposits. The favorable areas are: Virgin Valley, Humboldt County; northern Reese River Valley, Lander County; East Walker River, Lyon County; and Coaldale, Esmeralda County. Areas judged to be unfavorable are: Carol ''R'' prospect, Garfield Hills, Mineral County; and Meadow Valley (Panaca), Lincoln County. In the Virgin Valley area, the Canyon Rhyolite Formation contains as much as 27 ppM U 3 O 8 and is an excellent source rock. Uranium deposits in the underlying Virgin Valley Formation are small, but larger deposits may exist. The northern portion of the Reese River Valley contains several small uranium deposits but none of mineable grade or size. Rhyolitic volcanic rocks in the area contain above-average amounts of uranium, and larger deposits may lie beneath these potential source rocks. The East Walker River area may be part of a larger uranium province. Intrusive and extrusive rocks in the area contain above-average amounts of uranium, and low-grade supergene deposits were found. Large areas of potential source rocks and host rocks, and two small uranium deposits, were found in the Coaldale area. Many rhyolite plugs were also found. The Carol ''R'' prospect is an isolated uranium occurrence in Tertiary lacustrine rocks. Uranium deposits in Meadow Valley are in the Panaca Formation, a Pliocene lacustrine formation of varied lithology. The uranium deposits are small and low grade. It is unlikely that large-grade deposits will be found in this area

  18. James Blunt matuselaulude edetabeli tipus

    Index Scriptorium Estoniae

    2006-01-01

    Bereavement Registeri andmetel Suurbritannias matustel tellitavate laulude edetabelis: James Blunt "Goodbye My Lover", Robbie Williams "Angels", Jennifer Warnes ja Bill Medley "I've Had the Time Of My Life", Elton John "Candle in the Wind", Righteous Brothers "Unchained Melody"

  19. 78 FR 42757 - Marine Mammals; File No. 17411

    Science.gov (United States)

    2013-07-17

    ... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration RIN 0648-XC541 Marine Mammals; File No. 17411 AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric... permit has been issued to Dr. Jennifer Burns, University of Alaska Anchorage, Biology Department...

  20. 76 FR 57712 - Performance Review Board Membership

    Science.gov (United States)

    2011-09-16

    ... DEPARTMENT OF COMMERCE Performance Review Board Membership AGENCY: Economics and Statistics... the Performance Review Board (PRB) in accordance with the Economics and Statistics Administration's.... Bostic, Jr., Arnold A. Jackson, Theodore A. Johnson, Steven J. Jost, J. Steven Landefeld, Jennifer Madans...

  1. Managing Arthritis (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    Arthritis is a common chronic condition among Americans. As the population ages, the number of people with this condition is expected to increase dramatically. In this podcast, Dr. Jennifer Hootman discusses the importance of early diagnosis and management of arthritis.

  2. Western Indian Ocean Journal of Marine Science - Vol 10, No 2 (2011)

    African Journals Online (AJOL)

    Ophiocoma (Ophiurida: Ophiocomidae) species of the east coast of South Africa, including observations of parental care · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Jennifer Margaret Olbers, Yves Samyn, 137-154 ...

  3. Alternative Fuels Data Center: Federal Laws and Incentives for Hydrogen

    Science.gov (United States)

    agricultural equipment projects. For more information, see the Clean Agriculture website. Point of Contact include transit improvements, travel demand management strategies, congestion relief efforts (such as high and strategies. For more information, see the Ports Initiative website. Point of Contact Jennifer

  4. 1er février 2011-Première Présidente de la Confédération Suisse (1999)-Mme Ruth Dreifuss-Visite de la caverne expérimentale d’ATLAS avec F. Pauss, Chef des Relations internationales

    CERN Multimedia

    Maximilien Brice

    2011-01-01

    Photo 1-24:Collaboration ATLAS, Ancien Porte-parole P. Jenni+F. Pauss+Experte en pédagogie S. Forster+R. Dreifuss+C. Bossy+JP Bossy, visite de la caverne ATLAS Photo 25-40:Visite du Tunnel LHC au Point 1

  5. Assistant director of intramural sports and technology recognized for innovative contributions

    OpenAIRE

    Kropff, Catherine L.

    2009-01-01

    Jennifer Rezac, assistant director of intramural sports and technology at Virginia Tech, was recognized at the National Intramural-Recreational Sports Association (NIRSA) Annual Conference in Charlotte, N.C., in April for her contributions to the Virginia Tech Recreational Sports department.

  6. 77 FR 73009 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2012-12-07

    ... DEPARTMENT OF COMMERCE Submission for OMB Review; Comment Request The Department of Commerce will.... Frequency: Annually. Respondent's Obligation: Required to obtain benefits. OMB Desk Officer: Jasmeet Seehra... writing Jennifer Jessup, Departmental Paperwork Clearance Officer, (202) 482-0336, Department of Commerce...

  7. 78 FR 76811 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2013-12-19

    ... DEPARTMENT OF COMMERCE Submission for OMB Review; Comment Request The Department of Commerce will... occasion. Respondent's Obligation: Required to obtain or maintain benefits. OMB Desk Officer: OIRA... writing Jennifer Jessup, Departmental Paperwork Clearance Officer, (202) 482-0336, Department of Commerce...

  8. Less Weight, Less Pain (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    Being overweight contributes to many health problems. Over 50 million people in the U.S. have arthritis, a painful inflammation of the joints. In this podcast, Dr. Jennifer Hootman discusses the importance of maintaining a healthy weight to help manage arthritis.

  9. Staff Development: Cafe Style

    Science.gov (United States)

    Arns, Jennifer

    2008-01-01

    In most cases, memorable learning opportunities are fun, collaborative, and influential. Jennifer Arns, instructional programs director for the Organization for Education Technology and Curriculum, outlines the EdTech Professional Development Cadre, a refreshing and engaging PD approach. (Contains 3 resources.)

  10. Enzymatic activity of the cellulolytic complex produced by trichoderma reesei. Enzymatic hydrolysis of cellulose

    International Nuclear Information System (INIS)

    Alfonsel Jaen, M.; Negro, M.J.; Saez, R.; Martin Moreno, C.

    1986-01-01

    The enzymatic activity characterization of the cellulolytic complex obtained from Trichoderma reese QM 9414 and the influence of the enzymatic hydrolysis conditions on the hydrolysis yield are studied. Pure cellulose and native or alkali pretreated biomass from Onopordum nervosum have been used as substrates. The values of pH, temperature, substrate concentration and enzyme-substrate ratio for the optimum activity of that complex, evaluated as glucose and reducing sugars productions, have been selected. Previous studies on enzymatic hydrolysis of O. nervosum have shown a remarkable effect of the alkaline pretreatments on the final hydrolysis yield. (author). 10 figs.; 10 refs

  11. Radiotherapy for retinoblastoma

    International Nuclear Information System (INIS)

    Murayama, Shigeyuki; Kagami, Yoshikazu; Tokuue, Koichi; Sumi, Minako; Ikeda, Hiroshi; Kaneko; Akihiro

    1999-01-01

    A retrospective chart review was made of the patients with retinoblastoma received eye conservative therapy between 1980 and 1992. Of 112, 77 had bilateral disease and 35 had unilateral disease. A definitive external radiation therapy (ERT) was used in 106 eyes and ERT combined with concurrent or adjuvant therapy in 29 eyes. Five-year cumulative eye-ball conservation rate for Reese-Ellsworth classification group I to V were 95%, 95.5%, 93.3%, 100% and 58.5%, respectively. Useful vision (>0.01) was maintained in 90.2% of 61 eyes which were treated by definitive ERT initially and experienced no local recurrence. (author)

  12. 78 FR 14984 - Marine Mammals; File No. 17411

    Science.gov (United States)

    2013-03-08

    ... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration RIN 0648-XC541 Marine Mammals; File No. 17411 AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric.... Jennifer Burns, University of Alaska Anchorage, Biology Department, Anchorage, AK, has applied in due form...

  13. Contact Lens Safety (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    Contact lenses are a convenient and effective alternative to traditional eye glasses, but improper care and use can result in severe damage to the eyes. In this podcast, Dr. Jennifer Cope discusses the importance of proper care and use of contact lenses.

  14. In Memoriam: James Harlan Steele (1913—2013)

    Centers for Disease Control (CDC) Podcasts

    2014-05-19

    Drs. Jennifer McQuiston and Casey Barton Behravesh talk with Dr. Myron Schultz about the legendary Dr. James Harlan Steele.  Created: 5/19/2014 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 5/20/2014.

  15. Browse Title Index

    African Journals Online (AJOL)

    Items 451 - 500 of 644 ... C Chimphambano, I O Komolafe, A S Muula .... Desirée Witte, Mari Kirsten, Cheryl Louw, Bagrey Ngwira, John C. Victor, Paul H. Gillard, ... Jennifer J. Hull, Nigel Cunliffe, Khuzwayo C. Jere, Sung-Sil Moon, Yuhuan Wang, ...

  16. 77 FR 8216 - Request for Stakeholder Comments on “National Travel and Tourism Strategy”

    Science.gov (United States)

    2012-02-14

    ... ``National Travel and Tourism Strategy'' AGENCY: International Trade Administration, Department of Commerce... ``National Travel and Tourism Strategy'' (``Strategy''), to be produced by the Task Force on Travel and... sent to: Tourism[email protected] . Written comments may be sent to: Jennifer Pilat, 1401...

  17. Pop / Tõnis Kahu

    Index Scriptorium Estoniae

    Kahu, Tõnis, 1962-

    2002-01-01

    Heliplaatidest Darren Hayes "Spin". John Paul Jones "The Thunderthief". Chessie "Overnight". Jennifer Lopez "J To Tha L-O! The Remixes". Destiny's Child "This Is The Remix". Prince "The Rainbow Children. Celine Dion "A New Day Has Come". Cray "Undo". Wilco "Yankee Hotel Foxtrot"

  18. African Journal of Reproductive Health - Vol 6, No 2 (2002)

    African Journals Online (AJOL)

    Jennifer Smit, Lynn McFadyen, Abigail Harrison, Khangelani Zuma. Indigenous Healing Practices and Self-Medication amongst Pregnant Women in Cape Town, South Africa. Naeemah Abrahams, Rachel Jewkes, Zodumo Mvo. Tetanus Immunity among Pregnant Women Attending Antenatal Care in Dar es Salaam, ...

  19. 77 FR 18787 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2012-03-28

    ... DEPARTMENT OF COMMERCE Submission for OMB Review; Comment Request The Department of Commerce will...'s Obligation: Required to obtain benefits. OMB Desk Officer: Jasmeet Seehra, Fax number (202) 395... Jennifer Jessup, Departmental Paperwork Clearance Officer, (202) 482-0336, Department of Commerce, Room...

  20. 78 FR 77098 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2013-12-20

    ... DEPARTMENT OF COMMERCE Submission for OMB Review; Comment Request The Department of Commerce will... retain benefits. Copies of the above information collection proposal can be obtained by calling or writing Jennifer Jessup, Departmental Paperwork Clearance Officer, (202) 482-0336, Department of Commerce...

  1. 78 FR 47275 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2013-08-05

    ... DEPARTMENT OF COMMERCE Submission for OMB Review; Comment Request The Department of Commerce will... obtain benefits. Copies of the above information collection proposal can be obtained by calling or writing Jennifer Jessup, Departmental Paperwork Clearance Officer, (202) 482-0336, Department of Commerce...

  2. 75 FR 36062 - Availability of Conservation Seat and Diving Operations Seat for the Flower Garden Banks National...

    Science.gov (United States)

    2010-06-24

    ... Conservation Seat and Diving Operations Seat for the Flower Garden Banks National Marine Sanctuary Advisory... Flower Garden Banks National Marine Sanctuary Advisory Council: Conservation and Diving Operations... Jennifer Morgan, NOAA--Flower Garden Banks National Marine Sanctuary, 4700 Avenue U, Bldg. 216, Galveston...

  3. Beyond Barbie and Mortal Kombat: New perspectives on gender and gaming, edited by Yasmin B. Kafai et al. [book review

    Directory of Open Access Journals (Sweden)

    Gina Serafin-Persson

    2009-03-01

    Full Text Available Review of Yasmin B. Kafai, Carrie Heeter, Jill Denner, and Jennifer Y. Sun, eds. Beyond Barbie and Mortal Kombat: New perspectives on gender and gaming. Cambridge, MA: MIT Press, 2008. $29.95 (371p ISBN 978-0-262-11319-9.

  4. Reforming Social Policy: Changing Perspectives on Sustainable ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Reforming Social Policy: Changing Perspectives on Sustainable Human Development. Book cover Reforming Social Policy: Changing Perspectives on Sustainable Human Development. Directeur(s):. Daniel Morales-Gómez, Necla Tschirgi, and Jennifer L. Moher. Maison(s) d'édition: IDRC. 1 janvier 1999. ISBN :.

  5. 77 FR 31863 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2012-05-30

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... unwarranted invasion of personal privacy. Name of Committee: National Human Genome Research Institute Special..., Human Genome Research, National Institutes of Health, HHS) Dated: May 22, 2012. Jennifer S. Spaeth...

  6. 76 FR 10909 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2011-02-28

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome..., National Human Genome Research Institute, National Institutes of Health, 5635 Fishers Lane, Suite 4076, MSC..., Human Genome Research, National Institutes of Health, HHS). Dated: February 18, 2011. Jennifer S. Spaeth...

  7. 76 FR 36930 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2011-06-23

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... unwarranted invasion of personal privacy. Name of Committee: National Human Genome Research Institute Special..., Human Genome Research, National Institutes of Health, HHS) Dated: June 17, 2011. Jennifer S. Spaeth...

  8. 77 FR 35991 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2012-06-15

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome... Human Genome Research Institute, National Institutes of Health, 5635 Fishers Lane, Suite 4075, Bethesda.... 93.172, Human Genome Research, National Institutes of Health, HHS) Dated: June 8, 2012. Jennifer S...

  9. 75 FR 8977 - National Human Genome Research Institute; Notice of Closed Meeting

    Science.gov (United States)

    2010-02-26

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Human Genome..., National Human Genome Research Institute, National Institutes of Health, 5635 Fishers Lane, Suite 4076, MSC..., Human Genome Research, National Institutes of Health, HHS) Dated: February 18, 2010. Jennifer Spaeth...

  10. 75 FR 5707 - Revising Standards Referenced in the Acetylene Standard

    Science.gov (United States)

    2010-02-04

    ...: Occupational Safety and Health Administration (OSHA), Labor. ACTION: Proposed rule; withdrawal. SUMMARY: With this document, OSHA is withdrawing the proposed rule that accompanied its direct-final rule revising... and press inquiries: Contact Jennifer Ashley, Director, OSHA Office of Communications, Room N-3647, U...

  11. A demonstration of mobile phone deployment to support the ...

    African Journals Online (AJOL)

    A demonstration of mobile phone deployment to support the treatment of acutely ill children under five in Bushenyi district, Uganda. Jerome Kabakyenga, Celestine Barigye, Jennifer Brenner, Samuel Maling, Denise Buchner, Alberto Nettle-Aquirre, Nalini Singhal, Teddy Kyomuhangi, David Tumusiime, Janet Finch, Stuart ...

  12. A DATABASE FOR TRACKING TOXICOGENOMIC SAMPLES AND PROCEDURES WITH GENOMIC, PROTEOMIC AND METABONOMIC COMPONENTS

    Science.gov (United States)

    A Database for Tracking Toxicogenomic Samples and Procedures with Genomic, Proteomic and Metabonomic Components Wenjun Bao1, Jennifer Fostel2, Michael D. Waters2, B. Alex Merrick2, Drew Ekman3, Mitchell Kostich4, Judith Schmid1, David Dix1Office of Research and Developmen...

  13. Accelerating discovery with open-source technology at eLife

    OpenAIRE

    Penfold, Naomi

    2017-01-01

    Accelerating discovery with open-source technology. Talks presented May 2017.Files can be found at https://github.com/npscience/eLife-innovation-May2017-presentation.These slides are derived from a deck shared by Jennifer McLennan. All other sources acknowledged throughout the presentation.

  14. Plaadisoovitus

    Index Scriptorium Estoniae

    2005-01-01

    Uutest helisalvestistest Chemical Brothers "Push The Button", "Hedvig Hanson, Andre Maaker", Ashanti "Concrete Rose", "Brazilian Girls", Pain "Dancing With the Dead", Moby "Hotel", Damien Rice "O-b-sides", Jennifer Lopez "Rebirth", De-Phazz "Natural Take", "Arash", "Legends Of Rock'n'Roll", "Playboy: The Mansion

  15. 77 FR 38583 - Meeting of the United States Travel and Tourism Advisory Board

    Science.gov (United States)

    2012-06-28

    ... Tourism Advisory Board AGENCY: International Trade Administration, U.S. Department of Commerce. ACTION... the United States Travel and Tourism Advisory Board (Board). The agenda may change to [email protected] trade.gov . FOR FURTHER INFORMATION CONTACT: Jennifer Pilat, the United States Travel and Tourism...

  16. 77 FR 2720 - Proposed Agreement and Covenant Not To Sue for the Colville Post & Poles Superfund Site, Stevens...

    Science.gov (United States)

    2012-01-19

    .... MacDonald, Assistant Regional Counsel, U.S. Environmental Protection Agency, Region 10, 1200 Sixth Avenue, Suite 900, Seattle, Washington 98101; fax: (206) 553-1762; email: MacDonald[email protected] . FOR FURTHER INFORMATION CONTACT: Jennifer G. MacDonald, Assistant Regional Counsel, U.S. Environmental...

  17. 77 FR 8072 - Semiannual Regulatory Flexibility Agenda

    Science.gov (United States)

    2012-02-13

    ... six months. ADDRESSES: Comments should be addressed to Jennifer J. Johnson, Secretary of the Board... Regulatory and Deregulatory Actions, which is coordinated by the Office of Management and Budget under... pledged; and certain other elements including a strategic analysis of the company's plans for maintaining...

  18. 78 FR 7442 - Federal Property Suitable as Facilities To Assist the Homeless

    Science.gov (United States)

    2013-02-01

    ... following addresses: Coast Guard: Commandant, United States Coast Guard, Attn: Jennifer Stomber, 2100 Second... Facilities To Assist the Homeless AGENCY: Office of the Assistant Secretary for Community Planning and... surplus Federal property reviewed by HUD for suitability for use to assist the homeless. FOR FURTHER...

  19. Sibling Rivalry (For Parents)

    Science.gov (United States)

    ... needs. For example, if one likes to go outdoors, take a walk or go to the park. ... can help you determine whether your family might benefit from professional help and refer you to local behavioral health resources. Reviewed by: Jennifer Shroff Pendley, PhD Date ...

  20. Temporal Analysis of Andes Virus and Sin Nombre Virus Infections of Syrian Hamsters

    Science.gov (United States)

    2007-05-01

    Microbiology . All Rights Reserved. Temporal Analysis of Andes Virus and Sin Nombre Virus Infections of Syrian Hamsters Victoria Wahl-Jensen,1 Jennifer...Ye, C., J. Prescott , R. Nofchissey, D. Goade, and B. Hjelle. 2004. Neutralizing antibodies and Sin Nombre virus RNA after recovery from hantavirus

  1. Stopping Strokes (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    Stroke is a leading cause of disability in the U.S. Recognizing the symptoms and getting immediate treatment can decrease the chance of permanent disability and even death. In this podcast, Dr. Jennifer Foltz discusses the importance of getting immediate treatment for a stroke.

  2. 75 FR 36089 - Payment System Risk Policy; Daylight Overdraft Posting Rules

    Science.gov (United States)

    2010-06-24

    ... FEDERAL RESERVE SYSTEM [OP-1385] Payment System Risk Policy; Daylight Overdraft Posting Rules... Payment System Risk Policy, the Board is announcing posting rules for a new same-day automated clearing... Kirkpatrick, Senior Financial Services Analyst, Payment System Risk (202-452-2796), or Jennifer Davidson...

  3. A NOVEL EFFECT OF DIOXIN: EXPOSURE DURING PREGNANCY SEVERELY IMPAIRS MAMMARY GLAND DIFFERENTIATION

    Science.gov (United States)

    A novel effect of dioxin: Exposure during pregnancy severely impairs mammary gland differentiation.Beth A. Vorderstrasse1, Suzanne E. Fenton2, Andrea A. Bohn3, Jennifer A. Cundiff1, and B. Paige Lawrence1,3,4 1Department of Pharmaceutical Sciences, Washington State Universi...

  4. CD review: Giving voice to hope: music of Liberian refugees | Thorn ...

    African Journals Online (AJOL)

    Title: Giving voice to hope: music of Liberian refugees (2009). One compact disk and booklet. Production supervision by Barry Tonge, Michael Frishkopf, Nancy Hanneman, Ellis Pourbaix and Jennifer Woronuk. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT.

  5. 77 FR 73089 - Cambria Investment Management, L.P. and Cambria ETF Trust; Notice of Application

    Science.gov (United States)

    2012-12-07

    ... Investment Management, L.P. and Cambria ETF Trust; Notice of Application November 30, 2012. AGENCY... (e) certain registered management investment companies and unit investment trusts outside of the same... Jennifer L. Sawin, Branch Chief, at (202) 551-6821 (Division of Investment Management, Office of Investment...

  6. 78 FR 29331 - Proposed Information Collection; Comment Request; Western Alaska Community Development Quota Program

    Science.gov (United States)

    2013-05-20

    ... before July 19, 2013. ADDRESSES: Direct all written comments to Jennifer Jessup, Departmental Paperwork... economies in western Alaska. CDQ and prohibited species quota (PSQ) allocations are made to CDQ groups.... Information is collected only through quota transfers in this collection. II. Method of Collection Respondents...

  7. 76 FR 65411 - Specialty Crops; Import Regulations; Proposed Pistachio Import Requirements

    Science.gov (United States)

    2011-10-21

    ..., or E-mail: [email protected] or [email protected] . Small businesses may request... the proposed regulations, ``pistachio'' would mean the nut of the pistachio tree, Pistachia vera.... Pages 326-359. \\5\\ Eaton, David L.; Jennifer E. Hobden; and Bruce J. Kelman. 2002. Aflatoxin in...

  8. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. BRIAN CORMIER. Articles written in Journal of Genetics. Volume 96 Issue 4 September 2017 pp 681-685 RESEARCH NOTE. Clinical utility of a 377 gene custom next-generation sequencing epilepsy panel · JEN BEVILACQUA ANDREW HESSE BRIAN CORMIER JENNIFER DAVEY ...

  9. 76 FR 14674 - National Institute on Deafness and Other Communication Disorders; Notice of Closed Meeting

    Science.gov (United States)

    2011-03-17

    ... Deafness and Other Communication Disorders; Notice of Closed Meeting Pursuant to section 10(d) of the... Deafness and Other Communication Disorders Special Emphasis Panel; Review of Research Career Enhancement... Disorders, National Institutes of Health, HHS) Dated: March 11, 2011. Jennifer S. Spaeth, Director, Office...

  10. 76 FR 30179 - National Institute on Deafness and Other Communication Disorders Notice of Closed Meeting

    Science.gov (United States)

    2011-05-24

    ... Deafness and Other Communication Disorders Notice of Closed Meeting Pursuant to section 10(d) of the... constitute a clearly unwarranted invasion of personal privacy. Name of Committee: Communication Disorders... Communicative Disorders, National Institutes of Health, HHS) Dated: May 18, 2011. Jennifer S. Spaeth, Director...

  11. Developing Army Leaders: Lessons for Teaching Critical Thinking in Distributed, Resident, and Mixed-Delivery Venues

    Science.gov (United States)

    2014-01-01

    Arulampalam, Naylor, and Smith, 2004; Cantwell, Archer, and Bourke , 2001; Hoskins, Newstead, and Dennis, 1997); race (Miller and Ewell, 2005; Talbert...1996, pp. 26–48. Cantwell, Robert, Jennifer Archer, and Sid Bourke , “A Comparison of the Academic Experiences and Achievement of University

  12. 78 FR 66899 - Proposed Information Collection; Comment Request; Commercial Fisheries Seafood Processor Survey

    Science.gov (United States)

    2013-11-07

    ... plant characteristics, plant ownership, operating costs, capital costs, labor and revenue related to the... before January 6, 2014. ADDRESSES: Direct all written comments to Jennifer Jessup, Departmental Paperwork..., analysis of cost and revenue information for the seafood processing plant and other activities of the plant...

  13. EFFECTS OF DIBUTYL PHTHALATE IN MALE RABBITS FOLLOWING IN UTERO, ADOLESCENT OR POST-PUBERTAL EXPOSURE

    Science.gov (United States)

    Effects of dibutyl phthalate in male rabbits following in utero, adolescent, or post-pubertal exposureTy T. Higuchi1, Jennifer S. Palmer1, L. Earl Gray Jr2., and D. N. Rao Veeramachaneni11Animal Reproduction and Biotechnology Laboratory, Colorado State University, Fort

  14. AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination.

    Science.gov (United States)

    Kobayashi, Maki; Aida, Masatoshi; Nagaoka, Hitoshi; Begum, Nasim A; Kitawaki, Yoko; Nakata, Mikiyo; Stanlie, Andre; Doi, Tomomitsu; Kato, Lucia; Okazaki, Il-mi; Shinkura, Reiko; Muramatsu, Masamichi; Kinoshita, Kazuo; Honjo, Tasuku

    2009-12-29

    To initiate class switch recombination (CSR) activation-induced cytidine deaminase (AID) induces staggered nick cleavage in the S region, which lies 5' to each Ig constant region gene and is rich in palindromic sequences. Topoisomerase 1 (Top1) controls the supercoiling of DNA by nicking, rotating, and religating one strand of DNA. Curiously, Top1 reduction or AID overexpression causes the genomic instability. Here, we report that the inactivation of Top1 by its specific inhibitor camptothecin drastically blocked both the S region cleavage and CSR, indicating that Top1 is responsible for the S region cleavage in CSR. Surprisingly, AID expression suppressed Top1 mRNA translation and reduced its protein level. In addition, the decrease in the Top1 protein by RNA-mediated knockdown augmented the AID-dependent S region cleavage, as well as CSR. Furthermore, Top1 reduction altered DNA structure of the Smu region. Taken together, AID-induced Top1 reduction alters S region DNA structure probably to non-B form, on which Top1 can introduce nicks but cannot religate, resulting in S region cleavage.

  15. The Portraiture of Nick: Scene Two, the Middle Years

    Science.gov (United States)

    Bicehouse, Vaughn L.

    2012-01-01

    In 2007, the Autism Society of America (ASA) estimated that 1.5 million Americans and their families were affected by autism. As the current Autistic Spectrum Disorder (ASD) prevalence rates continue to rise (10%-17% each year) so does the awareness that ASD is no respecter of persons. ASD touches children of every racial, ethnic, and…

  16. Im Wind / Mari Vallisoo ; tõlk. Gisbert Jänicke

    Index Scriptorium Estoniae

    Vallisoo, Mari, 1950-2013

    2003-01-01

    Sisu: Im Wind = Tuulega ; Zwei Frauen = Kaks naist ; In Gedanken an Aleksander Levin = aleksander Levinile mõteldes ; Jetzt im Dunkel = Nüüd pimedas ; Fragen = Küsimused ; Der Zwillingsbruder = Kaksikvend

  17. Ten years of transition and... / Rika Ishii, Nick Sten

    Index Scriptorium Estoniae

    Ishii, Rika

    1999-01-01

    Ülevaade majandusreformidest Baltimaades ja Baltimaade majandussuhetest Euroopa Liidu ning Venemaaga. Tabel: SKP, inflatsioon, väliskaubandus ja välisinvesteeringud Eestis, Lätis, Leedus ja Kesk- ja Ida-Euroopa riikides aastatel 1991-1998

  18. Functional properties and structural requirements of the plasmid pMV158-encoded MobM relaxase domain.

    Science.gov (United States)

    Fernández-López, Cris; Pluta, Radoslaw; Pérez-Luque, Rosa; Rodríguez-González, Lorena; Espinosa, Manuel; Coll, Miquel; Lorenzo-Díaz, Fabián; Boer, D Roeland

    2013-07-01

    A crucial element in the horizontal transfer of mobilizable and conjugative plasmids is the relaxase, a single-stranded endonuclease that nicks the origin of transfer (oriT) of the plasmid DNA. The relaxase of the pMV158 mobilizable plasmid is MobM (494 residues). In solution, MobM forms a dimer through its C-terminal domain, which is proposed to anchor the protein to the cell membrane and to participate in type 4 secretion system (T4SS) protein-protein interactions. In order to gain a deeper insight into the structural MobM requirements for efficient DNA catalysis, we studied two endonuclease domain variants that include the first 199 or 243 amino acid residues (MobMN199 and MobMN243, respectively). Our results confirmed that the two proteins behaved as monomers in solution. Interestingly, MobMN243 relaxed supercoiled DNA and cleaved single-stranded oligonucleotides harboring oriTpMV158, whereas MobMN199 was active only on supercoiled DNA. Protein stability studies using gel electrophoresis and mass spectrometry showed increased susceptibility to degradation at the domain boundary between the N- and C-terminal domains, suggesting that the domains change their relative orientation upon DNA binding. Overall, these results demonstrate that MobMN243 is capable of nicking the DNA substrate independently of its topology and that the amino acids 200 to 243 modulate substrate specificity but not the nicking activity per se. These findings suggest that these amino acids are involved in positioning the DNA for the nuclease reaction rather than in the nicking mechanism itself.

  19. Asthma patients prefer Respimat® Soft Mist™ Inhaler to Turbuhaler®

    Directory of Open Access Journals (Sweden)

    Rick Hodder

    2009-05-01

    Full Text Available Rick Hodder1, Pat Ray Reese2, Terra Slaton31Divisions of Pulmonary and Critical Care, University of Ottawa, Ottawa, Ontario, Canada; 2Reese Associates Consulting LLC, Cary, North Carolina, USA; 3Consultant, West Columbia, South Carolina, USAAbstract: Device satisfaction and preference are important patient-reported outcomes to consider when choosing inhaled therapy. A subset of adults (n = 153 with moderate or severe asthma participating in a randomized parallel-group, double-dummy trial that compared the efficacy and safety of 12 weeks’ treatment with budesonide delivered via Respimat® Soft Mist™ Inhaler (SMI (200 or 400 µg bd or Turbuhaler® dry powder inhaler (400 µg bd, completed a questionnaire on patient device preference and satisfaction (PASAPQ as part of a psychometric validation. As the study used a double-dummy design to maintain blinding, patients used and assessed both devices, rating their satisfaction with, preference for, and willingness to continue using each device. The mean age of patients was 41 years, 69% were female and the mean duration of disease was 16 years. Total PASAPQ satisfaction scores were 85.5 and 76.9 for Respimat® SMI and Turbuhaler® respectively (p < 0.0001; 112 patients (74% preferred Respimat® SMI and 26 (17% preferred Turbuhaler®. Fourteen subjects (9% indicated no preference for either inhaler. Willingness to continue using Respimat® SMI was higher than that for Turbuhaler® (mean scores: 80/100 and 62/100, respectively. Respimat® SMI was preferred to Turbuhaler® by adult asthma patients who used both devices in a clinical trial setting.Keywords: asthma, Respimat® Soft Mist™ Inhaler, Turbuhaler®

  20. Healthy Contact Lens Wear and Care

    Centers for Disease Control (CDC) Podcasts

    2014-02-04

    In this podcast, CDC’s Dr. Jennifer Cope explains some basic steps for proper wear and care of soft contact lenses.  Created: 2/4/2014 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 2/4/2014.

  1. Music Genre as Method

    OpenAIRE

    Timothy Laurie

    2014-01-01

    A review of Jennifer C. Lena, Banding Together: How Communities Create Genres in Popular Music (Princeton University Press, 2012), Michelle Phillipov, Death Metal and Music Criticism: Analysis at the Limits(Lexington Books, 2012) and Graham St John, Global Tribe: Technology, Spirituality and Psytrance (Equinox Publishing, 2012). 

  2. 75 FR 36447 - Notice of Availability of Draft Environmental Impact Statement and Public Meetings for the...

    Science.gov (United States)

    2010-06-25

    ... be brought to the attention of Ms. Jennifer Davis no later than July 8, 2010, to provide NRC staff...), located at One White Flint North, 11555 Rockville Pike (first floor), Rockville, Maryland, 20852. Members... occupational health, air quality, water resources, waste management, geology and soils, noise, ecology...

  3. Attempted - to -Phase Conversion of Croconic Acid via Ball Milling

    Science.gov (United States)

    2017-05-18

    ARL-TN-0824 MAY 2017 US Army Research Laboratory Attempted α- to β-Phase Conversion of Croconic Acid via Ball Milling by...Laboratory Attempted α- to β-Phase Conversion of Croconic Acid via Ball Milling by Steven W Dean, Rose A Pesce-Rodriguez, and Jennifer A Ciezak...

  4. 76 FR 11264 - Submission for OMB Review; Comment Request

    Science.gov (United States)

    2011-03-01

    ... from Jennifer Merrill (USITC, tel. no. 202-205-3188). Hearing-impaired persons can obtain information... well as labor unions or representative groups of workers, U.S. importers and foreign exporters, and...'s shipments and purchases from various sources; (part III) financial data, including income-and-loss...

  5. Interview with Steve Parks

    Science.gov (United States)

    Hitchcock, Jennifer

    2016-01-01

    Jennifer Hitchcock interviews community activist and director of Syracuse University's Composition and Cultural Rhetoric doctoral program, Steve Parks. They discuss Parks's working-class background, career path, influences, and activism. Parks also considers the direction of the field of composition and rhetoric and expresses optimism for the…

  6. 78 FR 20686 - Federal Property Suitable as Facilities To Assist the Homeless

    Science.gov (United States)

    2013-04-05

    ...-8145; Coast Guard: Commandant, United States Coast Guard, Attn: Jennifer Stomber, 2100 Second St. SW... Facilities To Assist the Homeless AGENCY: Office of the Assistant Secretary for Community Planning and... surplus Federal property reviewed by HUD for suitability for use to assist the homeless. FOR FURTHER...

  7. 75 FR 68374 - Federal Property Suitable as Facilities To Assist the Homeless

    Science.gov (United States)

    2010-11-05

    ...: Commandant, United States Coast Guard, Attn: Jennifer Stomber, 2100 Second St., SW., Stop 7901, Washington... Facilities To Assist the Homeless AGENCY: Office of the Assistant Secretary for Community Planning and... surplus Federal property reviewed by HUD for suitability for possible use to assist the homeless. FOR...

  8. 78 FR 79000 - Federal Property Suitable as Facilities To Assist the Homeless

    Science.gov (United States)

    2013-12-27

    ... Guard: Commandant, United States Coast Guard, Attn: Jennifer Stomber, 2100 Second St. SW., Stop 7901... Facilities To Assist the Homeless AGENCY: Office of the Assistant Secretary for Community Planning and... surplus Federal property reviewed by HUD for suitability for use to assist the homeless. FOR FURTHER...

  9. 77 FR 75642 - Federal Property Suitable as Facilities to Assist the Homeless

    Science.gov (United States)

    2012-12-21

    ...: Commandant, United States Coast Guard, Attn: Jennifer Stomber, 2100 Second St. SW., Stop 7901, Washington, DC... Facilities to Assist the Homeless AGENCY: Office of the Assistant Secretary for Community Planning and... surplus Federal property reviewed by HUD for suitability for use to assist the homeless. FOR FURTHER...

  10. 78 FR 31572 - Federal Property Suitable as Facilities to Assist the Homeless

    Science.gov (United States)

    2013-05-24

    ...: Commandant, United States Coast Guard, Attn: Jennifer Stomber, 2100 Second St. SW., Stop 7901, Washington, DC... Facilities to Assist the Homeless AGENCY: Office of the Assistant Secretary for Community Planning and... surplus Federal property reviewed by HUD for suitability for use to assist the homeless. FOR FURTHER...

  11. 76 FR 2702 - Federal Property Suitable as Facilities To Assist the Homeless

    Science.gov (United States)

    2011-01-14

    ..., Arlington, VA 22202; (703) 601-2545; COAST GUARD: Commandant, United States Coast Guard, Attn: Jennifer... Facilities To Assist the Homeless AGENCY: Office of the Assistant Secretary for Community Planning and... surplus Federal property reviewed by HUD for suitability for possible use to assist the homeless. FOR...

  12. 77 FR 9681 - Federal Property Suitable as Facilities To Assist the Homeless

    Science.gov (United States)

    2012-02-17

    ...: Commandant, United States Coast Guard, Attn: Jennifer Stomber, 2100 Second St. SW., Stop 7901, Washington, DC... Facilities To Assist the Homeless AGENCY: Office of the Assistant Secretary for Community Planning and... surplus Federal property reviewed by HUD for suitability for use to assist the homeless. FOR FURTHER...

  13. 75 FR 60777 - Federal Property Suitable as Facilities To Assist the Homeless

    Science.gov (United States)

    2010-10-01

    ...: Commandant, United States Coast Guard, Attn: Jennifer Stomber, 2100 Second St., SW., Stop 7901, Washington... Facilities To Assist the Homeless AGENCY: Office of the Assistant Secretary for Community Planning and... surplus Federal property reviewed by HUD for suitability for possible use to assist the homeless. FOR...

  14. 78 FR 27417 - Federal Property Suitable as Facilities To Assist the Homeless

    Science.gov (United States)

    2013-05-10

    ... Guard: Commandant, United States Coast Guard, Attn: Jennifer Stomber, 2100 Second St. SW., Stop 7901... Facilities To Assist the Homeless AGENCY: Office of the Assistant Secretary for Community Planning and..., excess, and surplus Federal property reviewed by HUD for suitability for use to assist the homeless. FOR...

  15. 76 FR 76984 - Federal Property Suitable as Facilities To Assist the Homeless

    Science.gov (United States)

    2011-12-09

    ..., Arlington, VA 22202: (571) 256-8145; COAST GUARD: Commandant, United States Coast Guard, Attn: Jennifer... Facilities To Assist the Homeless AGENCY: Office of the Assistant Secretary for Community Planning and... surplus Federal property reviewed by HUD for suitability for use to assist the homeless. FOR FURTHER...

  16. 78 FR 13883 - Federal Property Suitable as Facilities To Assist the Homeless

    Science.gov (United States)

    2013-03-01

    ..., Washington, DC 20024, (202) 401-0787; Coast Guard: Commandant, United States Coast Guard, Attn: Jennifer... Facilities To Assist the Homeless AGENCY: Office of the Assistant Secretary for Community Planning and... surplus Federal property reviewed by HUD for suitability for use to assist the homeless. FOR FURTHER...

  17. 77 FR 41441 - Federal Property Suitable as Facilities To Assist the Homeless

    Science.gov (United States)

    2012-07-13

    ... Guard: Commandant, United States Coast Guard, Attn: Jennifer Stomber, 2100 Second St. SW., Stop 7901... Facilities To Assist the Homeless AGENCY: Office of the Assistant Secretary for Community Planning and... surplus Federal property reviewed by HUD for suitability for use to assist the homeless. FOR FURTHER...

  18. Preparing Minority Populations for Emergencies: Connecting to Build a More Resilient Community

    Science.gov (United States)

    2012-12-01

    downtown regional financial institutions. To avert the threat, and in part to stabilize the financial markets , it was decided to perform a controlled...Takeuchi, and Jennifer Kotler . Always Connected: The New Digital Media Habits of Young Children. New York: The Joan Ganz Cooney Center at Sesame

  19. 77 FR 52694 - Marine Mammals; File No. 17324

    Science.gov (United States)

    2012-08-30

    ... permitting process and solicit comments on the application and accompanying draft environmental assessment... or other auxiliary aids should be directed to Jennifer Skidmore, (301)427-8401 (voice) or (301)713... proposed activity is humane and does not represent any unnecessary risks to the health and welfare of...

  20. "Teaching Case": ComprehensiveCare and the Failed Implementation of an Electronic Health Records System

    Science.gov (United States)

    Gomillion, David L.

    2017-01-01

    Administrator Jennifer Stanton attempts to adopt an Electronic Health Records system at ComprehensiveCare, a multispecialty healthcare practice. Consultants from the vendor provide guidance to the organization, but do not provide that guidance in a way that the non-technical administrator understands. The project experiences escalation of…

  1. 76 FR 69730 - Pesticide Products; Receipt of Applications to Register New Uses

    Science.gov (United States)

    2011-11-09

    ... Protection Agency, 1200 Pennsylvania Ave. NW., Washington, DC 20460-0001 or Biopesticides and Pollution... greens subgroup 5B, turnip greens, sweet corn, fruiting vegetable group 8-10, citrus fruit group 10-10, pome fruit group 11-10. Contact: Jennifer Urbanski, Registration Division, (703) 347-0156, urbanski...

  2. Proper Lens Care (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    Wearing contact lenses is a convenient way to improve vision without having to wear glasses. But unlike glasses, improper care and maintenance of lenses can result in severe eye problems, including blindness. In this podcast, Dr. Jennifer Cope discusses the importance of proper lens hygiene and maintenance.

  3. Popnädal. Billboard 200 Albumid Top 20 / Jaan Tamm

    Index Scriptorium Estoniae

    Tamm, Jaan

    2002-01-01

    Ansambli The Smiths 20. sünnipäeva puhul ilmunud joonisfilmist. Jennifer Lopezist filmis "Enough". Peter Gabrieli albumist "Up". Duo Elton John ja Bernie autasustamisest Music Industry Trust galal. Duubelplaadist Yann Tiersen "C'Etait ICI". Filmist muusiku Gram Parsoni elust. Iiri poistebändist Westlife

  4. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Clinical utility of a 377 gene custom next-generation sequencing epilepsy panel · JEN BEVILACQUA ANDREW HESSE BRIAN CORMIER JENNIFER DAVEY DEVANSHI PATEL KRITIKA SHANKAR HONEY V. REDDI · More Details Abstract Fulltext PDF. Epilepsy is one of the most common neurological disorders with about ...

  5. 75 FR 66099 - Ocean Transportation Intermediary License Applicants

    Science.gov (United States)

    2010-10-27

    ... Logistics, Inc. (NVO), 17890 Castleton Street, Suite 398, City of Industry, CA 91748, Officers: Jennifer X... (Qualifying Individual), Application Type: QI Change. Concert Group Logistics, Inc. (NVO & OFF), 1430 Branding... Individual), Daniel Para, CEO, Application Type: QI Change. De Well Logistics LLC dba De Well Logistics, dba...

  6. 77 FR 51824 - Environmental and Related Services

    Science.gov (United States)

    2012-08-27

    ... . FOR FURTHER INFORMATION CONTACT: Project Leader Jennifer Powell (202- 205-3450 or [email protected] ) or Deputy Project Leader Joann Peterson (202-205-3032 or [email protected] ) for... related services, that, to the extent practicable: Estimates the size of the U.S. and global markets for...

  7. Perceptions of School Principals on Participation in Professional Learning Communities as Job-Embedded Learning

    Science.gov (United States)

    Gaudioso, Jennifer A.

    2017-01-01

    Perceptions of School Principals on Participation in Professional Learning Communities as Job-Embedded Learning Jennifer Gaudioso Principal Professional Learning Communities (PPLCs) have emerged as a vehicle for professional development of principals, but there is little research on how principals experience PPLCs or how districts can support…

  8. Dipeptidyl peptidase-4 inhibitors in the management of type 2 diabetes: safety, tolerability, and efficacy

    Directory of Open Access Journals (Sweden)

    Mary Elizabeth Cox

    2010-01-01

    Full Text Available Mary Elizabeth Cox1, Jennifer Rowell1, Leonor Corsino1, Jennifer B Green1,21Department of Medicine, Division of Endocrinology, Metabolism, and Nutrition. Duke University Medical Center, Durham, NC, USA; 2Department of Medicine, Division of Endocrinology, Durham Veterans Affairs Medical Center, Durham, NC, USAAbstract: Although glycemic control is an important and effective way to prevent and minimize the worsening of diabetes-related complications, type 2 diabetes is a progressive disease which often proves difficult to manage. Most affected patients will eventually require therapy with multiple medications in order to reach appropriate glycemic targets. The dipeptidyl peptidase-4 (DPP-4 inhibitors constitute a relatively new class of oral medications for the treatment of type 2 diabetes, which has become widely incorporated into clinical practice. This review summarizes the available data on the efficacy, safety, and tolerability of these medications.Keywords: type 2 diabetes, pharmacotherapy, DPP-4 inhibitor, sitagliptin, vildagliptin, saxagliptin, alogliptin, linagliptin

  9. Field Tests with Drilled Shafts in Tension in Frictional Soil

    DEFF Research Database (Denmark)

    Krabbenhøft, Sven; Damkilde, Lars; Andersen, Allan

    2009-01-01

    Three series of ten piles each have been installed. The lengths of the piles varied from 2 m to 6 m and the diameters were 14 cm, 25 cm and 60 cm. The piles were constructed above the ground water table using continuous flight augers and the concrete was placed by gravity free fall. All piles were...... tested to failure in axial uplift and the load-displacement relations were recorded and the results from the tests have been compared with theoretical values based on current design practice and the methods proposed by Fleming et al. and Reese & O'Neill seem to produce the best match with the test...

  10. Geologic map of the Bateman Spring Quadrangle, Lander County, Nevada

    Science.gov (United States)

    Ramelli, Alan R.; Wrucke, Chester T.; House, P. Kyle

    2017-01-01

    This 1:24,000-scale geologic map of the Bateman Spring 7.5-minute quadrangle in Lander County, Nevada contains descriptions of 24 geologic units and one cross section. Accompanying text includes full unit descriptions and references. This quadrangle includes lower Paleozoic siliciclastic sedimentary rocks of the Roberts Mountain allochthon, Miocene intrusive dikes, alluvial deposits of the northern Shoshone Range piedmont, and riverine deposits of the Reese and Humboldt rivers.Significant findings include: refined age estimates for the Ordovician-Cambrian Valmy Formation and Devonian Slaven Chert, based on new fossil information; and detailed mapping of late Quaternary fault traces along the Shoshone Range fault system.

  11. Preventing Pneumonia (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    2017-11-09

    Pneumonia is a lung infection that can result in severe illness and even death. Common symptoms include cough, fever, and difficulty breathing. In this podcast, Dr. Jennifer Farrar discusses ways to prevent pneumonia.  Created: 11/9/2017 by MMWR.   Date Released: 11/9/2017.

  12. Defining the Role of Public Health in Disaster Recovery: An Evaluation of State Public Health Planning Efforts

    Science.gov (United States)

    2013-03-01

    Brahmbhatt , Jennifer L. Chan, Edbert B. Hsu,Hani Mowafi, Thomas D. Kirsch, Asma Quereshi P. Gregg Greenough, “Public Health Preparedness of Post-Katrina...L. Chan, Edbert B. Hsu,Hani Mowafi, Thomas D. Kirsch, Asma Quereshi P. Gregg Greenough. “Public Health Preparedness of Post- Katrina and Rita

  13. Comparing rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on systemic dose and developmental effects

    NARCIS (Netherlands)

    Peter T. Theunissen; Bruce Beyer; Sonia Beken

    2016-01-01

    And co-authors William J. Breslin, Gregg D. Cappon, Connie L. Chen, Gary Chmielewski, Luc de Schaepdrijver, Brian Enright, Jennifer E. Foreman, Wafa Harrouk, Kok-Wah Hew, Alan M. Hoberman, Julia Y. Hui, Thomas B. Knudsen, Susan B. Laffan, Susan L. Makris, Matthew Martin, Mary Ellen McNerney,

  14. 75 FR 54161 - National Center for Complementary and Alternative Medicine; Notice of Closed Meeting

    Science.gov (United States)

    2010-09-03

    ... Complementary and Alternative Medicine; Notice of Closed Meeting Pursuant to section 10(d) of the Federal... Alternative Medicine Special Emphasis Panel; NCCAM Education Panel. Date: October 25-26, 2010. Time: 2 p.m. to... Alternative Medicine, National Institutes of Health, HHS) Dated: August 30, 2010. Jennifer S. Spaeth, Director...

  15. 76 FR 12744 - National Center for Complementary & Alternative Medicine; Notice of Closed Meeting

    Science.gov (United States)

    2011-03-08

    ... Complementary & Alternative Medicine; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory... Alternative Medicine Special Emphasis Panel, NCCAM Education Panel. Date: March 24-25, 2011. Time: 12 p.m. to... Alternative Medicine, National Institutes of Health, HHS) Dated: March 2, 2011. Jennifer S. Spaeth, Director...

  16. N/NC team claims three-peat softball championship title > U.S. Northern

    Science.gov (United States)

    ) 2007 (114) 2006 (88) 2005 (65) 2004 (51) 2003 (33) 2002 (12) N/NC team claims three-peat softball championship title By By SMSgt. Jennifer Thibault The NORAD-USNORTHCOM silver softball team presented their DOWNLOAD HI-RES / PHOTO DETAILS The NORAD-USNORTHCOM silver softball team presented their base championship

  17. 78 FR 30865 - Proposed Information Collection; Comment Request; Tilefish Individual Fishing Quota Program

    Science.gov (United States)

    2013-05-23

    ... Northeastern U.S. EEZ. II. Method of Collection The IFQ Allocation permit application, IFQ holder cap form, and... before July 22, 2013. ADDRESSES: Direct all written comments to Jennifer Jessup, Departmental Paperwork... applications to ensure that IFQ allocation holders are provided a statement of their annual catch quota, and...

  18. 77 FR 16209 - Proposed Information Collection; Comment Request; Tilefish Individual Fishing Quota Program

    Science.gov (United States)

    2012-03-20

    ... Northeastern U.S. EEZ. II. Method of Collection The IFQ Allocation permit application, IFQ ownership cap form... before May 21, 2012. ADDRESSES: Direct all written comments to Jennifer Jessup, Departmental Paperwork... applications to ensure that IFQ allocation owners are provided a statement of their annual catch quota, and for...

  19. 77 FR 16210 - Proposed Information Collection; Comment Request; Tilefish Individual Fishing Quota Program

    Science.gov (United States)

    2012-03-20

    ... Northeastern U.S. EEZ. II. Method of Collection The IFQ Allocation permit application, IFQ ownership cap form... before May 21, 2012. ADDRESSES: Direct all written comments to Jennifer Jessup, Departmental Paperwork... applications to ensure that IFQ allocation owners are provided a statement of their annual catch quota, and for...

  20. 76 FR 39152 - Agency Information Collection; Activity Under OMB Review; Report of Financial and Operating...

    Science.gov (United States)

    2011-07-05

    ... (RITA), Bureau of Transportation Statistics (BTS), DOT. ACTION: Notice. SUMMARY: In compliance with the... CONTACT: Jennifer Fabrizi, Office of Airline Information, RTS-42, Room E34-420, RITA, BTS, 1200 New Jersey... Affairs, Office of Management and Budget, 725-17th Street, NW., Washington, DC 20503, Attention: RITA/BTS...

  1. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (82nd, New Orleans, Louisiana, August 3-8, 1999). Magazine and Visual Communication Divisions.

    Science.gov (United States)

    Association for Education in Journalism and Mass Communication.

    The Magazine and Visual Communication Divisions section of the Proceedings contains the following 8 papers: "Beefcake, Breadwinner, or Babysitter: A Content Analysis of Male Images in Female-Targeted Magazine Advertising, 1978-1998" (Mikalee Dahle and Jennifer Greer); "The Impact of Larry Flynt: An Overview of One Publisher's Legal…

  2. Fiscal Policy in Urban Education. A Volume in Research in Education Fiscal Policy and Practice.

    Science.gov (United States)

    Roellke, Christopher, Ed.; Rice, Jennifer King, Ed.

    This volume focuses on school finance challenges in large urban school districts, fiscal accountability in these schools, and the fiscal dimensions of urban school reform. The 12 papers are (1) "School Finance and Urban Education Reform" (Christopher Roellke and Jennifer King Rice); (2) "Can Whole-School Reform Improve the…

  3. Proceedings of the Annual Meeting of the Association for Education in Journalism and Mass Communication (81st, Baltimore, Maryland, August 5-8, 1998). Advertising.

    Science.gov (United States)

    Association for Education in Journalism and Mass Communication.

    The Advertising section of the Proceedings contains the following 18 papers: "The Birth of Adwatches: Political Advertising Becomes Front-Page News" (Jennifer Greer); "A Cross-Cultural Comparison of the Effects of Source Credibility on Attitudes and Behavioral Intentions" (Kak Yoon, Choong Hyun Kim, and Min-Sun Kim);…

  4. Can this merger be saved?

    Science.gov (United States)

    Cliffe, S

    1999-01-01

    In this fictional case study, a merger that looked like a marriage made in heaven to those at corporate headquarters is feeling like an infernal union to those on the ground. The merger is between Synergon Capital, a U.S. financial-services behemoth, and Beauchamp, Becker & Company, a venerable British financial-services company with strong profits and an extraordinarily loyal client base of wealthy individuals. Beauchamp also boasts a strong group of senior managers led by Julian Mansfield, a highly cultured and beloved patriarch who personifies all that's good about the company. Synergon isn't accustomed to acquiring such companies. It usually encircles a poorly managed turnaround candidate and then, once the deal is done, drops a neutron bomb on it, leaving file cabinets and contracts but no people. Before acquiring Beauchamp, Synergon's macho men offered loud assurances that they would leave the tradition-bound company alone-provided, of course, that Beauchamp met the ambitious target numbers and showed sufficient enthusiasm for cross-selling Synergon's products to its wealthy clients. In charge of making the acquisition work is Nick Cunningham, one of Synergon's more thoughtful executives. Nick, who was against the deal from the start, is the face and voice of Synergon for Julian Mansfield. And Mansfield, in his restrained way, is angry at the constant flow of bureaucratic forms, at the rude demands for instant information, at the peremptory changes. He's even dropping broad hints at retirement. Nick has already been warned: if Mansfield goes, you go. Six commentators advise Nick on how to save his job by bringing peace and prosperity to the feuding couple.

  5. Facilitating University Education: A View From the North

    DEFF Research Database (Denmark)

    Wiewiura, Joachim Schmidt

    2016-01-01

    In this small essay, I will reflect on Michael Bérubé and Jennifer Ruth's arguments on the decline of educational professionalism in the United States. The purpose is to consider this loss of professionalism, and I will consider it in light of the arts and humanities in the Danish educational...

  6. Keep Contacts Clean (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    For millions of Americans, contact lenses are an effective form of vision correction and a popular alternative to glasses. However, if not properly worn and cared for, they can put wearers at risk for eye infections. In this podcast, Dr. Jennifer Cope discusses the importance of proper contact lens care.

  7. 77 FR 32530 - Antidumping or Countervailing Duty Order, Finding, or Suspended Investigation; Advance...

    Science.gov (United States)

    2012-06-01

    ... dumping or a countervailable subsidy (as the case may be) and of material injury. Upcoming Sunset Reviews... Proceedings Honey from Argentina (A-357-812) (2nd Review)......... Jennifer Moats, (202) 482-5047. Steel Concrete Reinforcing Bars from Belarus (A-822- David Goldberger, (202) 482-4136. 804) (2nd Review). Honey...

  8. PATTERNS OF SEVEN AND COMPLICATED MALARIA IN CHILDREN

    African Journals Online (AJOL)

    GB

    2017-09-01

    Sep 1, 2017 ... 2015 to March 2015 were included. Two control groups were included from the health facility and community. Simple random sampling technique ..... Tropical Medicine and International Health. 2006; 11:1136–1144. 30. Yordanos M, Jennifer B, Nicola W, Peter B,. Peter A, Melanie N, Gail D. Individual.

  9. 75 FR 47596 - Change in Bank Control Notices; Acquisition of Shares of Bank or Bank Holding Companies

    Science.gov (United States)

    2010-08-06

    ...: 1. Cecil R. Simmons, individually; and as a member of a group including Leonard P. Simmons, all of..., Raymondville, Texas (the ``Director Group''); Cecil R. Simmons and Juana Simmons, San Benito, Texas; Anita...; and Jennifer Stone and Tyler Stone, both of Dallas, Texas, together as a group acting in concert, to...

  10. Economics | Page 7 | IDRC - International Development Research ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Job seekers are converging on cities to find work, and in many countries urban ... IDRC's Jennifer Salahub shares her expertise on building safe and inclusive cities ... actively seek to attract and retain highly skilled foreign and domestic workers. ... An IDRC-funded project has enhanced the research capacity of 15 emerging ...

  11. 76 FR 29773 - National Center for Complementary & Alternative Medicine; Notice of Closed Meeting

    Science.gov (United States)

    2011-05-23

    ... Complementary & Alternative Medicine; Notice of Closed Meeting Pursuant to section 10(d) of the Federal Advisory... Complementary and Alternative Medicine, National Institutes of Health, HHS) Dated: May 17, 2011. Jennifer S... Alternative Medicine Special Emphasis Panel; NCCAM Education Panel. Date: June 23-24, 2011. Time: 8 a.m. to 12...

  12. 76 FR 11699 - Notice of Retrospective Review of DOT Existing Regulations

    Science.gov (United States)

    2011-03-03

    ... any digital presentation materials--March 10, 2011. Public Meeting--March 14, 2011--9:30 a.m.-4:30 p.m... should notify Jennifer Abdul-Wali at the address above by March 7, 2011; any digital presentation... name, title, country of citizenship, date of birth, passport number, and passport expiration date when...

  13. Practical Assessment, Research and Evaluation, 2001.

    Science.gov (United States)

    Rudner, Lawrence M., Ed.; Schafer, William D., Ed.

    2001-01-01

    This document consists of articles 23 through 26 published in the electronic journal "Practical Assessment, Research & Evaluation" in 2001: (23) "Effects of Removing the Time Limit on First and Second Language Intelligence Test Performance" (Jennifer Mullane and Stuart J. McKelvie); (24) "Consequences of (Mis)use of the Texas Assessment of…

  14. 75 FR 44271 - Office of the Director; Notice of Closed Meeting

    Science.gov (United States)

    2010-07-28

    ... 20892. Contact Person: Lawrence A. Tabak, PhD, DDS, Acting Director, Division of Program Coordination..., Building 31, Room 2C39, Bethesda, MD 20892, 301- 496-3571, lawrence[email protected] . This notice is being.... Dated: July 22, 2010. Jennifer Spaeth, Director, Office of Federal Advisory Committee Policy. [FR Doc...

  15. The Time Has Come to Create Meaning-Making Centers on College Campuses

    Science.gov (United States)

    Nash, Robert J.; Jang, Jennifer J. J.

    2013-01-01

    Robert J. Nash and Jennifer J. J. Jang argue that students have a great need to find a "meaning to live for," à la Victor Frankl, and make a case for creating a space for students and educators to contextualize learning experiences dealing with the universal, existential questions of life.

  16. Should Cost: A Strategy for Managing Military Systems Money

    Science.gov (United States)

    2016-03-01

    Defense AT&L: March-April 2016 38 Should Cost A Strategy for Managing Military Systems’ Money Jennifer A. Miller Miller is a Cost Analyst of the...and analysis O&S: operation and support or operation and sustainment, dependent on the context of phase of acquisition life cycle or money used

  17. 76 FR 39358 - Receipt of Several Pesticide Petitions Filed for Residues of Pesticide Chemicals in or on Various...

    Science.gov (United States)

    2011-07-06

    ... comment and with any disk or CD-ROM you submit. If EPA cannot read your comment due to technical... your requested changes. iv. Describe any assumptions and provide any technical information and/or data... decantation and filtration and finally, analysis by a LC/MS/MS method. Contact: Jennifer Urbanski, (703) 347...

  18. The 1958 Harlem School Boycott: Parental Activism and the Struggle for Educational Equity in New York City

    Science.gov (United States)

    de Forest, Jennifer

    2008-01-01

    In this article Jennifer de Forest details the 1958 Harlem school boycott and the resulting court case, "In the Matter of Charlene Skipwith." de Forest demonstrates how the Harlem Parents' Committee mobilized dissent in Harlem and led a boycott that effectively used the Supreme Court's 1954 decision in "Brown II," which…

  19. The transatlantic security rift and its implications for Baltic security / Jennifer Ann Moll

    Index Scriptorium Estoniae

    Moll, Jennifer Ann

    2004-01-01

    Autor vaatleb Euroopa riikide ja Ameerika Ühendriikide seisukohti julgeoleku, ohu hindamise ja sõjaliste jõudude kasutamise küsimustes ning erinevatest vaadetest tingitud julgeolekulõhe tekkimise ja süvenemise põhjuseid. Autor võrdleb Eesti, Läti, Leedu julgeoleku- ja välispoliitilisi eesmärke

  20. Permeabilization of ultraviolet-irradiated chinese hamster cells with polyethylene glycol and introduction of ultraviolet endonuclease from Micrococcus luteus

    International Nuclear Information System (INIS)

    Yarosh, D.B.; Setlow, R.B.

    1981-01-01

    Chinese hamster V-79 cells were made permeable by treatment with polyethylene glycol and then incubated with a Micrococcus luteus extract containing ultraviolet-specific endonuclease activity. This treatment introduced nicks in irradiated, but not in unirradiated, deoxyribonucleic acid. The nicks remained open for at least 3 h; there was no loss of endonuclease-sensitive sites, and no excision of dimers as measured by chromatography was detected. In addition, there was no increase in ultraviolet resistance in treated cells. This suggests that the absence of a significant amount of excision repair in rodent cells is due to the lack of both incision and excision capacity

  1. Harvard Education Letter. Volume 24, Number 1, January-February 2008

    Science.gov (United States)

    Chauncey, Caroline, Ed.

    2008-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Leadership Lessons From Schools Becoming "Data Wise" (Jennifer L. Steele and Kathryn Parker Boudett); (2) A Guide on the Side: Mentors Help New Leaders Prepare for Life in the…

  2. 77 FR 4560 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

    Science.gov (United States)

    2012-01-30

    ... Holding Company The notificants listed below have applied under the Change in Bank Control Act (12 U.S.C... bank holding company. The factors that are considered in acting on the notices are set forth in... Shattuck, Oklahoma. Board of Governors of the Federal Reserve System, January 24, 2012. Jennifer J. Johnson...

  3. 76 FR 67454 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

    Science.gov (United States)

    2011-11-01

    ... Holding Company The notificants listed below have applied under the Change in Bank Control Act (12 U.S.C... bank holding company. The factors that are considered in acting on the notices are set forth in... Reserve System, October 27, 2011. Jennifer J. Johnson, Secretary of the Board. [FR Doc. 2011-28269 Filed...

  4. 77 FR 8258 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

    Science.gov (United States)

    2012-02-14

    ... Holding Company The notificants listed below have applied under the Change in Bank Control Act (12 U.S.C... bank holding company. The factors that are considered in acting on the notices are set forth in... Governors of the Federal Reserve System, February 9, 2012. Jennifer J. Johnson, Secretary of the Board. [FR...

  5. 77 FR 26280 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

    Science.gov (United States)

    2012-05-03

    ... Holding Company The notificants listed below have applied under the Change in Bank Control Act (12 U.S.C... bank holding company. The factors that are considered in acting on the notices are set forth in... Governors of the Federal Reserve System, April 30, 2012. Jennifer J. Johnson, Secretary of the Board. [FR...

  6. 77 FR 42312 - Change in Bank Control Notices; Acquisitions of Shares of a Bank or Bank Holding Company

    Science.gov (United States)

    2012-07-18

    ... Holding Company The notificants listed below have applied under the Change in Bank Control Act (12 U.S.C... bank holding company. The factors that are considered in acting on the notices are set forth in... Lynnwood, Washington. Board of Governors of the Federal Reserve System, July 13, 2012. Jennifer J. Johnson...

  7. Where Is the Love? An Interrogation of Love in VH1's "Love and Hip Hop New York" and a Call to Educators to Respond to Anti-Love Messages

    Science.gov (United States)

    Edwards, Erica; Esposito, Jennifer

    2016-01-01

    In this article, Erica Edwards and Jennifer Esposito review the fourth season of "Love and Hip Hop New York," which is just a small part of the larger "Love and Hip Hop" reality TV series, which characterizes love through narrow representations of race, gender, and sexuality. Their analysis reports that this television program…

  8. 77 FR 38051 - Jones Canyon Hydro, LLC; Notice of Application for Amendment of Preliminary Permit Accepted for...

    Science.gov (United States)

    2012-06-26

    ... proposed reservoirs from 6,225 feet to 7,330 feet; and (7) change the name of the project from ``Jones Canyon Pumped Storage Project'' to ``Oregon Winds Pumped Storage''. FERC Contact: Jennifer Harper, 202..., using the eComment system at http://www.ferc.gov/docs-filing/ecomment.asp . You must include your name...

  9. Prospective Evaluation of Mental Health and Deployment Experience Among Women in the US Military

    Science.gov (United States)

    2012-07-06

    Beverly Sheppard, Katherine Snell, Steven Speigle, Kari Sausedo, Jennifer Walstrom, Martin White, James Whitmer, and Char- lene Wong; Madigan Army Medical...what physicians should know. J Gen Intern Med. 2006; 21(suppl 3):S5–S10. 13. Lindstrom KE, Smith TC, Wells TS, et al. The mental health of U.S

  10. 75 FR 60720 - Antidumping or Countervailing Duty Order, Finding, or Suspended Investigation; Advance...

    Science.gov (United States)

    2010-10-01

    ...-1391. Cased Pencils from the People's Republic of China (A- David Goldberger (202) 482-4136. 570-827) (3rd Review). Sparklers from the People's Republic of China (A-570- Jennifer Moats (202) 482-5047. 804... methodological or analytical issues relevant to the Department's conduct of Sunset Reviews is set forth in the...

  11. Native American Languages Act. Hearing before the Committee on Indian Affairs, United States Senate. One Hundred Eighth Congress, First Session on S. 575 To Amend the Native American Languages Act To Provide for the Support of Native American Language Survival Schools (May 15, 2003).

    Science.gov (United States)

    Congress of the U.S., Washington, DC. Senate Committee on Indian Affairs.

    This document includes statements given at this hearing by the following: William Y. Brown; John Cheek, Jennifer Chock; Rita Coosewon; David Dinwoodie; William Demmert, Jr.; Joycelyn DesRosier; Mary Hermes; Carla Herrera; Leanne Hinton; Holo Ho'opai; Hon. Daniel K. Inouye; Lawrence D. Kaplan; Keiki Kawaiaea; Rosalyn, LaPier; Lisa LaRonge; Vina…

  12. Where Professional Writing Meets Social Change: The Grant Proposal as a Site of Hospitality

    Science.gov (United States)

    Barrett, Kenna

    2013-01-01

    This essay builds upon prior attempts to foster linkages between the disciplines of Composition Studies and professional writing. I take up Jennifer Bay's suggestion that service learning is a site for connection and "hospitality" (in a Derridean sense) between these disciplines, advocating for and at the same time complicating Bay's proposal.…

  13. Computer/Information Science

    Science.gov (United States)

    Birman, Ken; Roughgarden, Tim; Seltzer, Margo; Spohrer, Jim; Stolterman, Erik; Kearsley, Greg; Koszalka, Tiffany; de Jong, Ton

    2013-01-01

    Scholars representing the field of computer/information science were asked to identify what they considered to be the most exciting and imaginative work currently being done in their field, as well as how that work might change our understanding. The scholars included Ken Birman, Jennifer Rexford, Tim Roughgarden, Margo Seltzer, Jim Spohrer, and…

  14. Disruptive Technology for Vector Control: the Innovative Vector Control Consortium and the US Military Join Forces to Explore Transformative Insecticide Application Technology for Mosquito Control Programmes

    Science.gov (United States)

    2015-09-26

    Jennifer Knapp1, Michael Macdonald2, David Malone3, Nicholas Hamon3 and Jason H. Richardson4* Abstract Malaria vector control technology has remained...control of Aedes albopictus in residential neighborhoods: from optimiza- tion to operation. PLoS One. 2014;9:e110035. 22. Lee VJ, Ow S, Heah H, Tan MY

  15. 77 FR 51686 - Specialty Crops; Import Regulations; New Pistachio Import Requirements

    Science.gov (United States)

    2012-08-27

    ... the new regulation, ``pistachio'' means the nut of the pistachio tree, Pistachia vera, whether inshell... Order No. 983. 2002. Pages 326-359. \\5\\ Eaton, David L.; Jennifer E. Hobden; and Bruce J. Kelman. 2002..., and New Mexico. AMS is committed to complying with the E-Government Act, to promote the use of the...

  16. 76 FR 63286 - Marine Mammals; File No. 15537

    Science.gov (United States)

    2011-10-12

    ..., Silver Spring, MD 20910; phone (301) 427-8401; fax (301) 713-0376; and Southeast Region, NMFS, 263 13th... INFORMATION CONTACT: Jennifer Skidmore or Amy Sloan, (301) 427-8401. SUPPLEMENTARY INFORMATION: On May 20... activities on the human environment in compliance with the National Environmental Policy Act of 1969 (42 U.S...

  17. 77 FR 45592 - Marine Mammals; File No. 17157

    Science.gov (United States)

    2012-08-01

    ..., Silver Spring, MD 20910; phone (301) 427-8401; fax (301) 713-0376; and Southeast Region, NMFS, 263 13th... INFORMATION CONTACT: Laura Morse or Jennifer Skidmore, (301) 427-8401. SUPPLEMENTARY INFORMATION: On May 21... 1969 (42 U.S.C. 4321 et seq.), a final determination has been made that the activity proposed is...

  18. Kunst rahvani ehk Kwangju biennaal / Siram

    Index Scriptorium Estoniae

    Siram, pseud., 1968-

    2004-01-01

    Biennaal "Tolmutera, veetilk" Lõuna-Koreas, avatud kuni 13. XI 2004. Kuraatorid Yongwoo Lee (New York, Soul), Kerry Brougher (Washington-distrikt), Suk-won Chang (Kwangju). City Light Award - Watercio Caldas (Brasiilia), Korea fondi preemia - Jennifer Allora ja Guillermo Calzadilla (Kuuba) jt. Johann Köleri nim. Positivistlik Kunsttööstuskool osales biennaali performance'iprogrammis

  19. Fulltext PDF

    Indian Academy of Sciences (India)

    ment of radioimmunoassays of peptide hormones' (7, 5). 8. Rosalind who helped discover the structure of DNA, or Ben- jamin who invented lighting conductor (8). 9. Emmanuelle, co-winner with Jennifer Doudna of Breakthrough. Prize for discovery of using CRISPR-Cas9 for genome editing. (11). 10. (3D, 23A) discovered ...

  20. Grand Theories of Personality Cannot Be Integrated

    Science.gov (United States)

    Wood, Alex; Joseph, Stephen

    2007-01-01

    Comments on the original article "A New Big Five: Fundamental Principles for an Integrative Science of Personality," by Dan P. McAdams and Jennifer L. Pals (see record 2006-03947-002). McAdams and Pals (April 2006) presented a new model to integrate the field of personality psychology. Cultural and evolutionary factors interact with an…

  1. Managing Arthritis (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    2017-10-19

    Arthritis is a common chronic condition among Americans. As the population ages, the number of people with this condition is expected to increase dramatically. In this podcast, Dr. Jennifer Hootman discusses the importance of early diagnosis and management of arthritis.  Created: 10/19/2017 by MMWR.   Date Released: 10/19/2017.

  2. Strategic Reading Groups: Guiding Readers in the Middle Grades

    Science.gov (United States)

    Berne, Jennifer; Degener, Sophie C.

    2012-01-01

    Strategic grouping can transform reading instruction in the middle grades from a hit-or-miss learning experience to a targeted, responsive one. This book features a practical and field-tested model for small-group differentiated reading instruction in Grades 4-8. Jennifer Berne and Sophie C. Degener offer a clear, detailed discussion of how to…

  3. Using iPads to Your Advantage

    Science.gov (United States)

    Zakrzewski, Jennifer L.

    2016-01-01

    In this article, middle school mathematics teacher Jennifer Zakrzewski describes how she successfully incorporated iPads and Apple TV (for projection of iPad screens) into her classroom while having her students solve a problem about mangoes. As Zakrzewski began a unit on multiplying and dividing fractions, she chose to start with the Mangoes…

  4. Learning about the Game: Designing Science Games for a Generation of Gamers

    Science.gov (United States)

    Chmiel, Marjee

    2012-01-01

    This paper is a response to "Challenges and Opportunities: Using a science-based video game in secondary school settings" by Rachel Muehrer, Jennifer Jenson, Jeremy Friedberg, and Nicole Husain. The article highlights two critical areas that I argue require more research in the studies of video games in education. The first area focuses on the…

  5. What I Wish My Professors Had Told Me

    Science.gov (United States)

    Collins, Jennifer

    2016-01-01

    What do you wish your undergraduate professors told you before you ever set foot in a classroom? Jennifer Collins, one such professor who prepares pre-service teachers, has a list of six "truths" she shares with her students. In this article, Collins outlines those pieces of advice, which include understanding your larger purpose,…

  6. Do Schools Owe a Special Duty of Care to "Special-Needs" Students?

    Science.gov (United States)

    Fossey, Richard; Russo, Charles J.

    2009-01-01

    Schools officials owe a duty of care to all the students in their custody. An emerging, but not unanimous, judicial consensus seems to agree that school board officials have a greater legal duty when supervising students with disabilities. A case on this important issue arose in "Jennifer C. v. Los Angeles Unified School District"…

  7. Briti asepeaminister arvustas Brüsselis võetud positsiooni / Evelyn Kaldoja

    Index Scriptorium Estoniae

    Kaldoja, Evelyn, 1980-

    2011-01-01

    Suurbritannia asepeaminister Nick Clegg kritiseeris peaminister David Cameroni seisukohti Euroopa Ülemkogul. Suurbritannia otsusest välja jääda Euroopa Liidu uuest valitsustevahelisest rahanduskokkuleppest

  8. Zehn Oden / Kristjan Jaak Peterson ; [Deutsch von Gisbert Jänicke

    Index Scriptorium Estoniae

    Peterson, Kristian Jaak, 1801-1822

    2001-01-01

    On ilmunud ka kogumikus "Iaak. Kristian Jaak Peterson 200" (Tln. : Eesti Keele Sihtasutus, 2001, lk. 105-122). Sisu: Der Mond = Kuu ; Freundschaft = Sõprus ; Der Sänger = Laulja ; An Gott = Jumalale ; Hoffnung = Lootus ; Ich muss Trinken. Liedchen = Ma pean jooma. Lauluke ; Ich bin wieder glücklich = Olen jälle õnnis ; Der Mensch = Inimene ; Sonnenuntergang = Päeva loojaminemine ; Herbst = Sügise.

  9. In the Nick of Time: Proactive Prevention of Obligation Violations

    DEFF Research Database (Denmark)

    Basin, David; Debois, Søren; Hildebrandt, Thomas

    2016-01-01

    We present a system model, an enforcement mechanism, and a policy language for the proactive enforcement of timed provisions and obligations. Our approach improves upon existing formalisms in two ways: (1) we exploit the target system's existing functionality to avert policy violations proactively...... declaratively express timed provisions and obligations as causal relationships between events, and DCR states explicitly represent pending obligations. As key technical results, we show that enforceability of DCR policies is decidable, we give a sufficient polynomial time verifiable condition for a policy...... to be enforceable, and we give an algorithm for determining from a DCR state a sequence of actions that discharge impending obligations....

  10. Ernst Enno etluskonkursil kõlas saja aasta tagune luule / Krista Kumberg

    Index Scriptorium Estoniae

    Kumberg, Krista, 1959-

    2007-01-01

    Läänemaal toimus maakondlik Ernst Ennole pühendatud etluskonkurss. E. Enno nimelise etluskonkursi 2007 "Saja aasta tagused luuletused" parimad etlejad olid Mike Richard Koch, Janno Allika, Hanna Ring, Karl Poll, Britta Sool, Antero Rea, Jennifer Cohen, Brita Kaljuvee, Eva-Maria Brock, Kaupo Engel, Liisi Räli, Laivi Kovalenko, Merje Viigand, Carmen Freimann, Rauno Punk, Maarja Palmiste

  11. Contact Lens Safety (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    2016-08-18

    Contact lenses are a convenient and effective alternative to traditional eye glasses, but improper care and use can result in severe damage to the eyes. In this podcast, Dr. Jennifer Cope discusses the importance of proper care and use of contact lenses.  Created: 8/18/2016 by MMWR.   Date Released: 8/18/2016.

  12. Stopping Strokes (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    2016-10-27

    Stroke is a leading cause of disability in the U.S. Recognizing the symptoms and getting immediate treatment can decrease the chance of permanent disability and even death. In this podcast, Dr. Jennifer Foltz discusses the importance of getting immediate treatment for a stroke.  Created: 10/27/2016 by MMWR.   Date Released: 10/27/2016.

  13. Pain Management (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    2017-06-08

    Arthritis is one of the most common chronic conditions in the United States. Unfortunately, as the population ages, it’s only expected to increase. In this podcast, Dr. Jennifer Hootman discusses ways to manage the pain of arthritis.  Created: 6/8/2017 by MMWR.   Date Released: 6/8/2017.

  14. Bagatellid : maailm / Nele-Eva Steinfeld, Harry Liivrand, Ivo Heinloo

    Index Scriptorium Estoniae

    Steinfeld, Nele-Eva

    2010-01-01

    Uudiseid maailmast: Helilooja Jennifer Higdon pälvis Pulitzeri preemia. Fabio Luisist sai Metropolitan Opera esimene külalisdirigent. "Operalia" võitjad Sonya Yoncheva ja Stefan Pop. Lahkus metsosopran Giulietta Simionato. Kaija Saariaho uus ooper "Emilie" Amsterdamis. Hollandi maineka jazziauhinna noppis Anton Goudsmit. Herbie Hancock tähisats juubelit. Jagati reggae- ja maailmamuusika auhindu. Ilmus Stevie Wonderi biograafia

  15. Armed Forces 1996 Equal Opportunity Survey: Administration, Datasets, and Codebook

    Science.gov (United States)

    1997-12-01

    Distribution Unlimited 19990712 025 Defense Manpower Data Center Survey & Program Evaluation Division 1600 Wilson Boulevard, Suite 400, Arlington, VA 22209...Texas at Austin), John Dovidio ( Colgate University), Joe Feagin (University of Florida), Jennifer Hochschild (Princeton University), James Jones... consumer -credit-information databases. Social security numbers of sample members with incomplete or out-of-date address information were forwarded to

  16. Al-Qaeda and Islamist Militant Influences on Tribal Dynamics: The Northern Mali and Northeastern Nigeria Regions

    Science.gov (United States)

    2016-01-05

    now  also  Mexico,  Central   America,  and  the  Caribbean.   Please  cite  data  as:  Salehyan,  Idean,   Cullen  S...Hendrix,  Jesse  Hamner,  Christina  Case,   Christopher  Linebarger,  Emily  Stull,  and  Jennifer   Williams .  "Social

  17. KEBIJAKAN POLITIK LUAR NEGERI FILIPINA PADA MASA PEMERINTAHAN RODRIGO DUTERTE TENTANG LAUT CINA SELATAN

    OpenAIRE

    BEATRICE G. P., JENNIFER

    2017-01-01

    2017 Jennifer Beatrice Glorianna Putri, E131 13 308. ???Kebijakan Politik Luar Negeri Filipina Pada Masa Pemerintahan Rodrigo Duterte tentang Laut Cina Selatan???, dibawah bimbingan Patrice Lumumba, selaku Pembimbing I, dan Aswin Baharuddin, selaku Pembimbing II, pada Jurusan Ilmu Hubungan Internasional, Fakultas Ilmu Sosial dan Ilmu Politik, Universitas Hasanuddin. Penelitian ini bertujuan untuk mendeskripsikan kebijakan politik luar negeri Filipi...

  18. Corporate Social Responsibility: A Cross Sectional Examination of Incentivization.

    Science.gov (United States)

    1995-09-01

    which address organizational behavior: Corporate Social Responsibility ( CSR ), Expense Preference Approach (EPA), Resource Dependency Theory (RDT...i V *>V CORPORATE SOCIAL RESPONSIBILITY : A CROSS SECTIONAL EXAMINATION OF INCENTIVIZATION THESIS Jennifer A. Block, B.S. First Lieutenant, USAF...Distribution/ Availability Codes Dist m Avail and/or Special \\&\\W 0\\1 CORPORATE SOCIAL RESPONSIBILITY : A CROSS SECTIONAL EXAMINATION OF

  19. Browse Title Index

    African Journals Online (AJOL)

    Items 51 - 71 of 71 ... Vol 3, No 1 (1999), What Women do in Wartime: gender and conflict in Africa, Details. Jennifer Chiriga. Vol 3, No 1 (1999), Whose Honour, Whose Humiliation: Women, Men and the Economic Crisis in South Korea, Details. Soung-ai Choi. Vol 4, No 2 (2000), Women in Politics and Decision Making in ...

  20. Stumbling Through: How Joel Klein Reinvented the New York City Schools

    Science.gov (United States)

    Viteritti, Joseph P.

    2012-01-01

    In this essay, the author reviews "Education Reform in New York City: Ambitious Change in the Nation's Most Complex School System," by Jennifer A. O'Day, Catherine S. Bitter, and Louis Gomez. The book under review explores a larger set of issues, and some time has passed. But many of the issues studied remain relevant and the consistent…

  1. Jails and Local Justice System Reform: Overview and Recommendations

    Science.gov (United States)

    Copp, Jennifer E.; Bales, William D.

    2018-01-01

    Over the past three decades, the number of people housed in local jails has more than tripled. Yet when it comes to reforming the nation's incarceration policies, write Jennifer Copp and William Bales, researchers, policymakers, and the public alike have focused almost exclusively on state and federal prisons. If you took a snapshot on a single…

  2. What Is the Problem? The Challenge of Providing Effective Teachers for All Children

    Science.gov (United States)

    Murnane, Richard J.; Steele, Jennifer L.

    2007-01-01

    Richard Murnane and Jennifer Steele argue that if the United States is to equip its young people with the skills essential in the new economy, high-quality teachers are more important than ever. In recent years, the demand for effective teachers has increased as enrollments have risen, class sizes have fallen, and a large share of the teacher…

  3. United States Army Special Operations Forces and Building Enduring Partner Enabler Capacity in Operation Enduring Freedom-Philippines

    Science.gov (United States)

    2014-05-22

    Monograph Director Christopher Marsh, Ph.D. , Seminar Leader Christopher T. Drew, COL, EN , Director, School of Advanced Military...56Robert Nolan , “Terror in the Philippines,” Foreign Policy Association Newsletter, 6 March 2003; Charles H. Briscoe...2007. Moroney, Jennifer, Beth Grill, Joe Hogler, Lianne Kennedy-Boudali, and Christopher Paul. How Successful Are US Efforts to Build Capacity in

  4. Facilitating University Education: A View from the North

    Science.gov (United States)

    Wiewiura, Joachim S.

    2016-01-01

    In this small essay, I will reflect on Michael Bérubé and Jennifer Ruth's arguments on the decline of educational professionalism in the United States. The purpose is to consider this loss of professionalism, and I will consider it in light of the arts and humanities in the Danish educational debate. Two reflections are presented: first, the…

  5. Sequence Classification: 390305 [

    Lifescience Database Archive (English)

    Full Text Available SOMERASE I TOPA (OMEGA-PROTEIN) (RELAXING ENZYME) (UNTWISTING ENZYME) (SWIVELASE) (TYPE I DNA TOPOISOMERASE) (NICKING-CLOSING ENZYME) || http://www.ncbi.nlm.nih.gov/protein/31794816 ...

  6. Nicholas J. Nagle | NREL

    Science.gov (United States)

    @nrel.gov | 303-384-6184 Research Interests Nick is interested in understanding how advanced feedstocks Technology (2015) "Acid-catalyzed algal biomass pretreatment for integrated lipid and carbohydrate-based

  7. The effect of irradiation on the DNA of cauliflower

    International Nuclear Information System (INIS)

    Harmey, M.A.

    1991-01-01

    The cellular DNA is one of the components most affected by ionizing radiation. Lesions caused range from single and double stranded breaks to chemical modification of bases depending on the radiation dosage and the metabolic status of the tissue. In attempting to assess the DNA damage induced by irradiation of vegetables in a speedy and convenient manner, we examined the effect on the DNA by subjecting cauliflower to a dose of 1 kGy. If DNA is nicked by irradiation, the extent of the damage can be assessed by using DNA polymerase to repair the nicks. Comparisons were made between irradiated and non irradiated cauliflower and incorporation of 32 p deoxy GTP in the presence of the Klenow fragment of DNA polymerase measured

  8. Proper Lens Care (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    2017-08-17

    Wearing contact lenses is a convenient way to improve vision without having to wear glasses. But unlike glasses, improper care and maintenance of lenses can result in severe eye problems, including blindness. In this podcast, Dr. Jennifer Cope discusses the importance of proper lens hygiene and maintenance.  Created: 8/17/2017 by MMWR.   Date Released: 8/17/2017.

  9. Proper Lens Care (A Minute of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    2017-08-17

    Wearing contact lenses is a convenient way to improve vision without having to wear glasses. But unlike glasses, improper care and maintenance of lenses can result in severe eye problems, including blindness. In this podcast, Dr. Jennifer Cope discusses the importance of proper lens hygiene and maintenance.  Created: 8/17/2017 by MMWR.   Date Released: 8/17/2017.

  10. Information Sharing from 9-1-1 Centers

    Science.gov (United States)

    2014-09-01

    Police Chief, 2014, http://www.policechiefmagazine.org/ magazine /index.cfm?fuseaction=display_arch&article_id=1199&issue _id=62007. 2 “9-1-1 History...Homeland Security Magazine ,51 discusses the pros and cons of using social media to 49 Jennifer E...Information Dilemmas in Biotechnology : Organizational Boundaries As Trust Production, NBER WorkingPaper No. 5199, National Bureau of Economic

  11. Soosaar Lucie-Smithi taktikepi all / Reet Varblane

    Index Scriptorium Estoniae

    Varblane, Reet, 1952-

    2004-01-01

    "Jumal saab inimeseks": Edward Lucie-Smithi kuraatoriprojekt Ateena Frissirase muuseumis 14. VII-12. IX ja Mark Soosaare kuraatoriprojekt Pärnu Uue Kunsti Muuseumis 5. VI-29. VIII. Sui Jianguo, Tim Maseini ja Jennifer Mehra, Olga Tobrelutsu, Genja Sheffi, Nikos Navridise, Jaan Toomiku, Michalis Manoussakise, Lembit Sarapuu, Kaljo Põllu ja tšehhi rühmituse Kamera Skura töödest

  12. Browse Author Index

    African Journals Online (AJOL)

    Skinner, Donald · Skinner, Donald · Skovdal, Morten · Sliep, Yvonne · Smillie, Kirsten · Smit, Jennifer A. Smith, Dawn K · Smith, Helen · Smith, Julia · Smith, Sarah · Snipstad, Mai Bente · Sodemann, Morten · Soko, Mavis · Sone, Albert Mouelle · Souza, Emmanuel · Spark-du Preez1, N · Spiegel, Paul B · Sprague, Courtenay

  13. Topology Control in Aerial Multi-Beam Directional Networks

    Science.gov (United States)

    2017-04-24

    Topology Control in Aerial Multi-Beam Directional Networks Brian Proulx, Nathaniel M. Jones, Jennifer Madiedo, Greg Kuperman {brian.proulx, njones...significant interference. Topology control (i.e., selecting a subset of neighbors to communicate with) is vital to reduce the interference. Good topology ...underlying challenges to topology control in multi-beam direction networks. Two topology control algorithms are developed: a centralized algorithm

  14. College Graduate with NCI Internship Gains Experience, Carries Chemistry into Medicine | Poster

    Science.gov (United States)

    For Jennifer Marshall, the skills learned through an internship at the National Cancer Institute (NCI) at Frederick have prepared her for the next step of her life—medical school. Marshall, who will be attending the West Virginia University School of Medicine in the fall, spent three summers in NCI at Frederick’s Summer Internship Program expanding her love and passion for

  15. Role of Mesenchymal-Derived Stem Cells in Stimulating Dormant Tumor Cells to Proliferate and Form Clinical Metastases

    Science.gov (United States)

    2017-07-01

    Clinical Metastases PRINCIPAL INVESTIGATOR: Rosandra Kaplan CONTRACTING ORGANIZATION: The Geneva Foundation Tacoma, WA 98402 REPORT DATE: July 2017...2017 4. TITLE AND SUBTITLE Role of Mesenchymal-Derived Stem Cells in Stimulating Dormant Tumor Cells to Proliferate and Form Clinical Metastases 5a...PRODUCTS:  publications, conference papers, and presentations ; Jennifer Zhu submitted an abstract and will present this work at the Annual

  16. Beware: It’s Mosquito Season (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    West Nile virus and other arboviruses are transmitted primarily through the bite of an infected mosquito or tick. These viruses cause thousands of people to get sick each summer. In 2012, there was a substantial increase in the number of West Nile virus cases reported in the U.S. In this podcast, Jennifer Lehman discusses ways to avoid being infected with an arbovirus.

  17. Schedule Analytics

    Science.gov (United States)

    2016-04-30

    Warfare, Naval Sea Systems Command Acquisition Cycle Time : Defining the Problem David Tate, Institute for Defense Analyses Schedule Analytics Jennifer...research was comprised of the following high- level steps :  Identify and review primary data sources 1...research. However, detailed reviews of the OMB IT Dashboard data revealed that schedule data is highly aggregated. Program start date and program end date

  18. BACTERICIDAL COATINGS ON TEXTILES FOR REMEDIATION OF INTERMICROBE ACTIVITY (BaCTeRIA) SUMMARY REPORT

    Science.gov (United States)

    2017-07-07

    TEXTILES FOR REMEDIATION OF INTERMICROBE ACTIVITY (BaCTeRIA) SUMMARY REPORT by Tobyn A. Branck Courtney M. Cowell Jennifer M. Rego and...October 2011 – September 2015 4. TITLE AND SUBTITLE BACTERICIDAL COATINGS ON TEXTILES FOR REMEDIATION OF INTERMICROBE ACTIVITY (BaCTeRIA) SUMMARY REPORT... REMEDIATION OF INTERMICROBE ACTIVITY (BaCTeRIA) SUMMARY REPORT Introduction The Biological Sciences and Technology Team (BSTT), Warfighter

  19. Application Development for Optimizing Patient Placement on Aeromedical Evacuation Flights: Proof-of-Concept

    Science.gov (United States)

    2018-01-12

    PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Brittany Fouts, Jennifer Serres, Ray Hill, Frank Ciarallo 5d. PROJECT NUMBER 5e. TASK NUMBER 5f...APPENDIX A – Flowchart for Graphical Prototype ...................................................................... 9 APPENDIX B – Proof-of-Concept App...would like to thank the programming team at the Department of Operational Analysis at the Air Force Institute of Technology at Wright-Patterson Air

  20. 76 FR 9071 - Advisory Committee on Historical Diplomatic Documentation; Notice of Meeting

    Science.gov (United States)

    2011-02-16

    ... notify Nick Sheldon, Office of the Historian (202-663-1123) no later than March 3, 2011 to provide date..., Advisory Committee on Historical Diplomatic Documentation, Department of State, Office of the Historian...

  1. Structure-guided Mutational Analysis of the Nucleotidyltransferase Domain of Escherichia coli DNA Ligase (LigA).

    Science.gov (United States)

    Wang, Li Kai; Zhu, Hui; Shuman, Stewart

    2009-03-27

    NAD(+)-dependent DNA ligases (LigA) are ubiquitous in bacteria, where they are essential for growth and present attractive targets for antimicrobial drug discovery. LigA has a distinctive modular structure in which a nucleotidyltransferase catalytic domain is flanked by an upstream NMN-binding module and by downstream OB-fold, zinc finger, helix-hairpin-helix, and BRCT domains. Here we conducted a structure-function analysis of the nucleotidyltransferase domain of Escherichia coli LigA, guided by the crystal structure of the LigA-DNA-adenylate intermediate. We tested the effects of 29 alanine and conservative mutations at 15 amino acids on ligase activity in vitro and in vivo. We thereby identified essential functional groups that coordinate the reactive phosphates (Arg(136)), contact the AMP adenine (Lys(290)), engage the phosphodiester backbone flanking the nick (Arg(218), Arg(308), Arg(97) plus Arg(101)), or stabilize the active domain fold (Arg(171)). Finer analysis of the mutational effects revealed step-specific functions for Arg(136), which is essential for the reaction of LigA with NAD(+) to form the covalent ligase-AMP intermediate (step 1) and for the transfer of AMP to the nick 5'-PO(4) to form the DNA-adenylate intermediate (step 2) but is dispensable for phosphodiester formation at a preadenylylated nick (step 3).

  2. Plaadid / Villu Koskaru

    Index Scriptorium Estoniae

    Koskaru, Villu, 1976-

    2003-01-01

    Uutest plaatidest Era "The Mass", Dannii Minogue "Neon Nights", Aaliyah "I Care 4 U", Linkin Park " Meteora", "Smash Hits 6", The Mighty Pop "Yellow", John Taylor "Rosslyn", Nick Cave & The Bad Seds "Nocturama"

  3. A Different Approach to Strategic Planning Using Appreciative Inquiry

    Directory of Open Access Journals (Sweden)

    Jason Openo

    2016-08-01

    Full Text Available The interview describes the integration of Appreciative Inquiry (AI into the strategic planning cycle at Medicine Hat College. Appreciative Inquiry can play a powerful role in initiating and managing change through the process of asking generative questions. AI increases the possibility of introducing successful and transformative change at all levels within an organization. The interview was conducted in December 2015 by Innovations in Practice Editor Jennifer Easter. Dans l’entretien, il s’agit de l’intégration de l’enquête appréciative (Appreciative Inquiry en cycle de planification stratégique au Medicine Hat College. L’enquête appréciative peut jouer un rôle vigoureux dans l’initiation et la gestion de changement par le processus de poser des questions génératrices. L’enquête appréciative augmente la possibilité d’introduire le changement réussi et significatif à tous les niveaux d’une organisation. L’entretien a été mené en décembre de 2015 par Jennifer Easter, la rédactrice d’Innovations in Practice.

  4. 75 FR 71787 - Advisory Committee On Historical Diplomatic Documentation; Notice of Meeting

    Science.gov (United States)

    2010-11-24

    ... session must notify Nick Sheldon, Office of the Historian (202-663-1123) no later than December 9, 2010... of State, Office of the Historian, Washington, DC 20520, telephone (202) 663-1123, (e-mail history...

  5. 76 FR 53165 - Advisory Committee on Historical Diplomatic Documentation; Notice of Meeting

    Science.gov (United States)

    2011-08-25

    ... planning to attend must notify Nick Sheldon, Office of the Historian (202-663-1123) no later than September... of State, Office of the Historian, Washington, DC 20520, telephone (202) 663-1123, (e-mail history...

  6. Pop / Tauno Maarpuu

    Index Scriptorium Estoniae

    Maarpuu, Tauno

    2006-01-01

    Heliplaatidest: Scandinavian Music Group "Hölmö rakkaus", Baron Zen "At The Mall", Cave, Nick & Warren Ellis "The Proposition. Original Soundtrack", Eläkeläiset "Humppasirkus", Warren Zevon "Reconsider Me: The Love Songs"

  7. Vene elektrivõrk : Gazprom on ebakindel gaasitarnija / Raimo Poom

    Index Scriptorium Estoniae

    Poom, Raimo

    2007-01-01

    Tallinnas toimunud rahvusvahelisel energiajulgeoleku konverentsil räägiti energia- ja keskkonnateemadel. Vene elektrivõrkude esindaja Marina Liborakina hoiatas Gazpromi vigade eest gaasi tarnimisel. Kommenteerib Briti nõustamisfirma E3G juhataja Nick Mabey

  8. Keep Contacts Clean (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    2015-09-03

    For millions of Americans, contact lenses are an effective form of vision correction and a popular alternative to glasses. However, if not properly worn and cared for, they can put wearers at risk for eye infections. In this podcast, Dr. Jennifer Cope discusses the importance of proper contact lens care.  Created: 9/3/2015 by MMWR.   Date Released: 9/3/2015.

  9. The spirituality of 'atheist' student in the secondary school of Athena royal of René Magritte of Lessines

    OpenAIRE

    Derjacques, Erica Agnes Rita

    2017-01-01

    This thesis analyses the spirituality of adolescent in two public schools in Belgium. The analysis is done using the book, Cultivating the spirit: How college can enhance students' inner lives by Jennifer Lindholm, Alexander and Helen Astin. The study focused on Five Spiritual Qualities: Spiritual Quest; Equanimity; Ethic of Caring; Charitable Involvement; and Ecumenical Worldview and Five Religious Qualities: Religious Commitment; Religious Engagement; Religious/Social Conservatism; Religiou...

  10. Learning for VMM + WTA Embedded Classifiers

    Science.gov (United States)

    2016-03-31

    Learning for VMM + WTA Embedded Classifiers Jennifer Hasler and Sahil Shah Electrical and Computer Engineering Georgia Institute of Technology...enabling correct classification of each novel acoustic signal (generator, idle car, and idle truck ). The classification structure requires, after...measured on our SoC FPAA IC. The test input is composed of signals from urban environment for 3 objects (generator, idle car, and idle truck

  11. Role of Mesenchymal Derived Stem Cells in Stimulating Dormant Tumor Cells to Proliferate and Form Clinical Metastases

    Science.gov (United States)

    2017-07-01

    Clinical Metastases PRINCIPAL INVESTIGATOR: Jeffrey Green CONTRACTING ORGANIZATION: The Geneva Foundation Tacoma, WA 98402 REPORT DATE: July 2017 TYPE...2016 - 14 June 2017 4. TITLE AND SUBTITLE Role of Mesenchymal-Derived Stem Cells in Stimulating Dormant Tumor Cells to Proliferate and Form Clinical ...and/or select agents. Nothing to report. 6. PRODUCTS: • publications, conference papers, and presentations ; Jennifer Zhu submitted an abstract and will

  12. Large-Scale Linear Optimization through Machine Learning: From Theory to Practical System Design and Implementation

    Science.gov (United States)

    2016-08-10

    IEEE, 2005. Mohsen Bayati, Christian Borgs , Jennifer Chayes, and Ric- cardo Zecchina. Belief propagation for weighted b- matchings on arbitrary...on automatic protocol behavior analysis and Resource management for hyper connected for IoT Services); the Center for Integrated Smart Sensors funded...maximum weight b-matching,” in International Conference on Artificial Intelligence and Statistics, 2007, pp. 195–202. [13] M. Bayati, C. Borgs , J

  13. Default, Cognitive, and Affective Brain Networks in Human Tinnitus

    Science.gov (United States)

    2015-10-01

    AWARD NUMBER: W81XWH-13-1-0491 TITLE: Default, Cognitive, and Affective Brain Networks in Human Tinnitus PRINCIPAL INVESTIGATOR: Jennifer R...SUBTITLE 5a. CONTRACT NUMBER Default, Cognitive and Affective Brain Networks in Human Tinnitus 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6...Release; Distribution Unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT Tinnitus is a major health problem among those currently and formerly in military

  14. Plaadid / Rein Vader, Heidi Purga, Tiiu Laks...[jt.

    Index Scriptorium Estoniae

    2008-01-01

    Uutest heliplaatidest Nick Cave & The Bad Seeds "Dig, Lazarus, Dig!", Erykah Badu "New Amerikah Part One", Leslie da Bass "Nights By Open Windows", Jack Johnson "Sleep Througth The Static", Janet Jackson "Discipline", "Rock & Roll City"

  15. Will we ever see their like again? Departing directors at the top US physics laboratories leave a discipline in search of inspired leadership

    CERN Multimedia

    1998-01-01

    Burt Richter stands down next August as director of the Stanford Linear Accelerator Centre. His departure follows that of Nick Samios from Brookhaven National Laboratory and the retirement next year of John Peoples from Fermilab.

  16. Pop / Mart Juur

    Index Scriptorium Estoniae

    Juur, Mart, 1964-

    2005-01-01

    Heliplaatidest: Nick Cave & The Bad Seeds "B-Sides & Rarities", Koneveljet "Hoax", Everything But The Girl "Adapt or Die. Ten Years of Remixes", Autechre "Untitled", Daedelus "Exquisite Corpse", Keane "Live recordings 2004", Iris Garrelfs "Specified Encounters"

  17. Electric Six : Ettevaatust! Kõrgepinge!

    Index Scriptorium Estoniae

    2007-01-01

    Ameerika rockansamblist Electric Six, albumitest "Fire", "Swizerland". Ameerika rockauljast-kitarristist Nick Oliveri'st, ansambli Mondo Generator (www.mondogenerator.com) albumist "Dead Planet: SonicSlowMotionTrails". Info festivalist: www.rabarock.delfi.ee / www.rabarock.ee

  18. Harbor porpoise - Passive acoustic monitoring of harbor porpoises in Puget Sound

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Drs. Marla Holt, Brad Hanson, and Candice Emmons of the NWFSC, along with efforts from the NWFSC dive team (coordinated by Nick Tolimieri), are currently conducting...

  19. Nick Jonas on Type 1 Diabetes | NIH MedlinePlus the Magazine

    Science.gov (United States)

    Skip to main content NIH MedlinePlus the Magazine NIH MedlinePlus Salud Download the Current Issue PDF [1.9 mb] Trusted Health Information from the National Institutes of Health Home Current Issue ...

  20. Výzkum diváka Strašnického divadla

    OpenAIRE

    Humlová, Jana

    2012-01-01

    This bachelor thesis focuses on marketing applied by theatres. Firstly there is a definition of marketing in general and then the thesis focuses on differences in marketing applied by cultural organizations, especially by theatres. Then it shows diverse types of theatres. Afterwards the thesis becomes less theoretical and gets more concrete and it explains the term marketing mix on example of Strašnice theatre. The practical part is represented by a marketing research. The purpose of the rese...

  1. Processing of Nonconjugative Resistance Plasmids by Conjugation Nicking Enzyme of Staphylococci

    Energy Technology Data Exchange (ETDEWEB)

    Pollet, Rebecca M.; Ingle, James D.; Hymes, Jeff P.; Eakes, Thomas C.; Eto, Karina Yui; Kwong, Stephen M.; Ramsay, Joshua P.; Firth, Neville; Redinbo, Matthew R. (Curtin U.); (Sydney); (UNC)

    2016-01-04

    Antimicrobial resistance inStaphylococcus aureuspresents an increasing threat to human health. This resistance is often encoded on mobile plasmids, such as pSK41; however, the mechanism of transfer of these plasmids is not well understood. In this study, we first examine key protein-DNA interactions formed by the relaxase enzyme, NES, which initiates and terminates the transfer of the multidrug resistance plasmid pSK41. Two loops on the NES protein, hairpin loops 1 and 2, form extensive contacts with the DNA hairpin formed at theoriTregion of pSK41, and here we establish that these contacts are essential for proper DNA cleavage and religation by the full 665-residue NES proteinin vitro. Second, pSK156 and pCA347 are nonconjugativeStaphylococcus aureusplasmids that contain sequences similar to theoriTregion of pSK41 but differ in the sequence predicted to form a DNA hairpin. We show that pSK41-encoded NES is able to bind, cleave, and religate theoriTsequences of these nonconjugative plasmidsin vitro. Although pSK41 could mobilize a coresident plasmid harboring its cognateoriT, it was unable to mobilize plasmids containing the pSK156 and pCA347 variantoriTmimics, suggesting that an accessory protein like that previously shown to confer specificity in the pWBG749 system may also be involved in transmission of plasmids containing a pSK41-likeoriT. These data indicate that the conjugative relaxase intransmechanism recently described for the pWBG749 family of plasmids also applies to the pSK41 family of plasmids, further heightening the potential significance of this mechanism in the horizontal transfer of staphylococcal plasmids.

    IMPORTANCEUnderstanding the mechanism of antimicrobial resistance transfer in bacteria such asStaphylococcus aureusis an important step toward potentially slowing the spread of antimicrobial-resistant infections. This work establishes protein-DNA interactions essential for the transfer of theStaphylococcus aureusmultiresistance plasmid pSK41 by its relaxase, NES. This enzyme also processed variantoriT-like sequences found on numerous plasmids previously considered nontransmissible, suggesting that in conjunction with an uncharacterized accessory protein, these plasmids may be transferred horizontally via a relaxase intransmechanism. These findings have important implications for our understanding of staphylococcal resistance plasmid evolution.

  2. Preparation of short cytosine-modified oligonucleotides by nicking enzyme amplification reaction

    Czech Academy of Sciences Publication Activity Database

    Ménová, Petra; Hocek, Michal

    2012-01-01

    Roč. 48, č. 55 (2012), s. 6921-6923 ISSN 1359-7345 R&D Projects: GA ČR GA203/09/0317 Institutional support: RVO:61388963 Keywords : cross - coupling reactions * nucleoside triphosphates * functionalized DNA * restriction endonucleases * polymerase incorporation Subject RIV: CC - Organic Chemistry Impact factor: 6.378, year: 2012

  3. RBS and SEM analysis of the nickel-fullerene hybrid systems

    Czech Academy of Sciences Publication Activity Database

    Vacík, Jiří; Naramoto, J.; Narumi, K.; Yamanoto, S.; Abe, J.

    2003-01-01

    Roč. 206, - (2003), s. 395-398 ISSN 0168-583X Institutional research plan: CEZ:AV0Z1048901 Keywords : nicke-fullerene hybrid Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 1.041, year: 2003

  4. Book Review: A Liberal Actor in a Realist World the European Union ...

    African Journals Online (AJOL)

    Abstract. Book Title: A Liberal Actor in a Realist World the European Union Regulatory State and the Global Political Economy of Energy. Book Author: Andreas Goldthau & Nick Sitter. Oxford University Press Oxford 2015. ISBN 9780198719595 ...

  5. 76 FR 28844 - Advisory Committee on Historical Diplomatic Documentation; Notice of Meeting

    Science.gov (United States)

    2011-05-18

    ... notify Nick Sheldon, Office of the Historian (202-663-1123) no later than June 2, 2011 to provide date of..., Department of State, Office of the Historian, Washington, DC 20520, telephone (202) 663-1123, (e-mail history...

  6. Folk, akustiline selline, on hambus Tristan Priimäel / Tristan Priimägi

    Index Scriptorium Estoniae

    Priimägi, Tristan, 1976-

    2004-01-01

    Heliplaatidest: Iron & Wine "Our Endless Numbered Days", Sufjan Stevens "Seven Swans", Joanna Newsom "The Milk-Eyed Mender", Nick Drake "Made to Love Magic", Kings Of Convenience "Riot On an Empty Street", White Magic "Through the Sun Door"

  7. Determination of p-y Curves using Finite Element Modelling for Bucket Foundation in Undrained Soft and Medium Clay

    DEFF Research Database (Denmark)

    Hvidberg, Mogens Bonde; Ibsen, Lars Bo

    In many years the types of foundation, such as monopiles and bucket foundation which are used in the offshore wind turbine industry, have been analysed analytically with formulations that are based on much slender piles, than are used today. Because of that, the analytical calculation...... is not describing the connection between the horizontal bearing capacity of the soil and the displacement of the foundation accurate, in particular for the bucket foundation because of the much smaller slenderness of the profile. Numerical modelling is used to examine that bearing capacity the bucket foundation has...... in soft and medium clay at different dimensions of the bucket, to a horizontal displacement. After that a mathematical formulation is determined, based on (Reese et al, 1975), so it is possible to get a more accurate result in an analytical calculation....

  8. The Activity of Cellulase from Thermophilic Fungi Isolated from CaneBagasses

    International Nuclear Information System (INIS)

    Aris-Toharisman; Akyunul-Jannah

    2000-01-01

    The activity of cellulase from thermophilic fungi isolated from canebagasses has been measured. This wild strain, named fungal strain PJ-2,secreted a large amount of cellulolytic enzyme components consisting of 0.46units of avicelase, 0.8 units of carboxymethyl cellulose hydrolizing enzyme(CMCase) and 0.5 units of β-glucosidase per ml of culture broth oncultivation in Mandels Reese medium for 7 days at 500 o C. These cellulasesproduction was lower than that of Trichoderma reesei NRRL 3653 producing 0.5units/ml avicelase, 1.6 units/ml CMCase and 0.4 units/ml ofβ-glucosidase cultivated in the same medium at 30 o C. However,thermophilic fungi may be potential to be exploited in lignocellulosedegradation at the tropical areas as the process usually needs temperature ofabove 50 o C. (author)

  9. Thermal and viscous effects on sound waves: revised classical theory.

    Science.gov (United States)

    Davis, Anthony M J; Brenner, Howard

    2012-11-01

    In this paper the recently developed, bi-velocity model of fluid mechanics based on the principles of linear irreversible thermodynamics (LIT) is applied to sound propagation in gases taking account of first-order thermal and viscous dissipation effects. The results are compared and contrasted with the classical Navier-Stokes-Fourier results of Pierce for this same situation cited in his textbook. Comparisons are also made with the recent analyses of Dadzie and Reese, whose molecularly based sound propagation calculations furnish results virtually identical with the purely macroscopic LIT-based bi-velocity results below, as well as being well-supported by experimental data. Illustrative dissipative sound propagation examples involving application of the bi-velocity model to several elementary situations are also provided, showing the disjoint entropy mode and the additional, evanescent viscous mode.

  10. Installation Restoration Program. Phase 2. Confirmation/Quantification. Stage 1. Reese Air Force Base, Lubbock, Texas. Volume 2. Appendices

    Science.gov (United States)

    1988-04-01

    12 XR7Jw - - DRILLNdL - SITE NAlE: SITE I.D: SITE LOCATION: 009 TDD #R6- DATE: ROLE DESIGNATION: .;] HOLE LOCATION: GROUND ELEV: TOP OF CASING FLEV...0 STAflDBY POWER IASB , 0 HP RP DESCRhIPTION VI~S~G ANDNELL~Rr~T~ T~V~L ~5~ .LLNGTh - IeA : - - - Flur27 AFF:m98 Well, Allt; ’PV$ - p I3 n I’I Figue...require a complete respect for safety by all team members to prevent injury or loss of life. 15.1 ORGANIZATION AND RESPONSIBILITIES There are eight roles

  11. Application of DNA Machineries for the Barcode Patterned Detection of Genes or Proteins.

    Science.gov (United States)

    Zhou, Zhixin; Luo, Guofeng; Wulf, Verena; Willner, Itamar

    2018-06-05

    The study introduces an analytical platform for the detection of genes or aptamer-ligand complexes by nucleic acid barcode patterns generated by DNA machineries. The DNA machineries consist of nucleic acid scaffolds that include specific recognition sites for the different genes or aptamer-ligand analytes. The binding of the analytes to the scaffolds initiate, in the presence of the nucleotide mixture, a cyclic polymerization/nicking machinery that yields displaced strands of variable lengths. The electrophoretic separation of the resulting strands provides barcode patterns for the specific detection of the different analytes. Mixtures of DNA machineries that yield, upon sensing of different genes (or aptamer ligands), one-, two-, or three-band barcode patterns are described. The combination of nucleic acid scaffolds acting, in the presence of polymerase/nicking enzyme and nucleotide mixture, as DNA machineries, that generate multiband barcode patterns provide an analytical platform for the detection of an individual gene out of many possible genes. The diversity of genes (or other analytes) that can be analyzed by the DNA machineries and the barcode patterned imaging is given by the Pascal's triangle. As a proof-of-concept, the detection of one of six genes, that is, TP53, Werner syndrome, Tay-Sachs normal gene, BRCA1, Tay-Sachs mutant gene, and cystic fibrosis disorder gene by six two-band barcode patterns is demonstrated. The advantages and limitations of the detection of analytes by polymerase/nicking DNA machineries that yield barcode patterns as imaging readout signals are discussed.

  12. Method for introducing unidirectional nested deletions

    Science.gov (United States)

    Dunn, J.J.; Quesada, M.A.; Randesi, M.

    1999-07-27

    Disclosed is a method for the introduction of unidirectional deletions in a cloned DNA segment. More specifically, the method comprises providing a recombinant DNA construct comprising a DNA segment of interest inserted in a cloning vector. The cloning vector has an f1 endonuclease recognition sequence adjacent to the insertion site of the DNA segment of interest. The recombinant DNA construct is then contacted with the protein pII encoded by gene II of phage f1 thereby generating a single-stranded nick. The nicked DNA is then contacted with E. coli Exonuclease III thereby expanding the single-stranded nick into a single-stranded gap. The single-stranded gapped DNA is then contacted with a single-strand-specific endonuclease thereby producing a linearized DNA molecule containing a double-stranded deletion corresponding in size to the single-stranded gap. The DNA treated in this manner is then incubated with DNA ligase under conditions appropriate for ligation. Also disclosed is a method for producing single-stranded DNA probes. In this embodiment, single-stranded gapped DNA, produced as described above, is contacted with a DNA polymerase in the presence of labeled nucleotides to fill in the gap. This DNA is then linearized by digestion with a restriction enzyme which cuts outside the DNA segment of interest. The product of this digestion is then denatured to produce a labeled single-stranded nucleic acid probe. 1 fig.

  13. Kinetic mechanism of human DNA ligase I reveals magnesium-dependent changes in the rate-limiting step that compromise ligation efficiency.

    Science.gov (United States)

    Taylor, Mark R; Conrad, John A; Wahl, Daniel; O'Brien, Patrick J

    2011-07-01

    DNA ligase I (LIG1) catalyzes the ligation of single-strand breaks to complete DNA replication and repair. The energy of ATP is used to form a new phosphodiester bond in DNA via a reaction mechanism that involves three distinct chemical steps: enzyme adenylylation, adenylyl transfer to DNA, and nick sealing. We used steady state and pre-steady state kinetics to characterize the minimal mechanism for DNA ligation catalyzed by human LIG1. The ATP dependence of the reaction indicates that LIG1 requires multiple Mg(2+) ions for catalysis and that an essential Mg(2+) ion binds more tightly to ATP than to the enzyme. Further dissection of the magnesium ion dependence of individual reaction steps revealed that the affinity for Mg(2+) changes along the reaction coordinate. At saturating concentrations of ATP and Mg(2+) ions, the three chemical steps occur at similar rates, and the efficiency of ligation is high. However, under conditions of limiting Mg(2+), the nick-sealing step becomes rate-limiting, and the adenylylated DNA intermediate is prematurely released into solution. Subsequent adenylylation of enzyme prevents rebinding to the adenylylated DNA intermediate comprising an Achilles' heel of LIG1. These ligase-generated 5'-adenylylated nicks constitute persistent breaks that are a threat to genomic stability if they are not repaired. The kinetic and thermodynamic framework that we have determined for LIG1 provides a starting point for understanding the mechanism and specificity of mammalian DNA ligases.

  14. Unique Helicase Determinants in the Essential Conjugative TraI Factor from Salmonella enterica Serovar Typhimurium Plasmid pCU1

    Energy Technology Data Exchange (ETDEWEB)

    McLaughlin, Krystle J.; Nash, Rebekah P.; Redinbo, Mathew R. (UNC)

    2014-06-16

    The widespread development of multidrug-resistant bacteria is a major health emergency. Conjugative DNA plasmids, which harbor a wide range of antibiotic resistance genes, also encode the protein factors necessary to orchestrate the propagation of plasmid DNA between bacterial cells through conjugative transfer. Successful conjugative DNA transfer depends on key catalytic components to nick one strand of the duplex DNA plasmid and separate the DNA strands while cell-to-cell transfer occurs. The TraI protein from the conjugative Salmonella plasmid pCU1 fulfills these key catalytic roles, as it contains both single-stranded DNA-nicking relaxase and ATP-dependent helicase domains within a single, 1,078-residue polypeptide. In this work, we unraveled the helicase determinants of Salmonella pCU1 TraI through DNA binding, ATPase, and DNA strand separation assays. TraI binds DNA substrates with high affinity in a manner influenced by nucleic acid length and the presence of a DNA hairpin structure adjacent to the nick site. TraI selectively hydrolyzes ATP, and mutations in conserved helicase motifs eliminate ATPase activity. Surprisingly, the absence of a relatively short (144-residue) domain at the extreme C terminus of the protein severely diminishes ATP-dependent strand separation. Collectively, these data define the helicase motifs of the conjugative factor TraI from Salmonella pCU1 and reveal a previously uncharacterized C-terminal functional domain that uncouples ATP hydrolysis from strand separation activity.

  15. Briti publik armastab King Kongi / Andris Feldmanis

    Index Scriptorium Estoniae

    Feldmanis, Andris, 1982-

    2006-01-01

    Briti filmiajakiri Empire lugejate filmiauhinnad : parim film "King Kong" (Peter Jackson), parim režii Steve Box, Nick Park "Wallace & Gromit - libaküüliku needus", parim meesnäitleja Johnny Depp, parim naisnäitleja Thandie Newton

  16. 78 FR 67927 - Foreign Trade Regulations (FTR): Mandatory Automated Export System Filing for All Shipments...

    Science.gov (United States)

    2013-11-13

    ... Internet at [email protected] ). FOR FURTHER INFORMATION CONTACT: Nick Orsini, Chief, Foreign Trade Division... 0607-AA50 Foreign Trade Regulations (FTR): Mandatory Automated Export System Filing for All Shipments... approval of new information collection requirements. [[Page 67928

  17. Wallace ja Gromit tulid Londonis linale / Andres Laasik

    Index Scriptorium Estoniae

    Laasik, Andres, 1960-2016

    2005-01-01

    Londonis esilinastus animafilm "Wallace ja Gromit : Libaküüliku needus" : režissöör Nick Park : Suurbritannia 2005. Kohal olid ka tegelastele hääle andnud Ralph Fiennes, Helena Bonham Carter ja Peter Sallis

  18. Pre-Processing Data Using Wavelet Transform and PCA Based on ...

    Indian Academy of Sciences (India)

    5

    wavelet theory in the last century, using this tool in the hydrology has been an ... These models are based on Statistical Learning Theory, which is ...... Hutcheson G and Nick S 1999 The multivariate social scientist: Introductory statistics using.

  19. "Of comics and men: A cultural history of American comic books," by Jean-Paul Gabilliet

    Directory of Open Access Journals (Sweden)

    Drew Morton

    2013-06-01

    Full Text Available Jean-Paul Gabilliet. Of comics and men: A cultural history of American comic books. Translated by Bart Beaty and Nick Nguyen. Jackson: University Press of Mississippi, 2010, hardcover, $55.00 (390p, ISBN 978-1604732672.

  20. Minority Undergraduate Research in Prostate Cancer: Bridging Opportunities for Postbaccalaureate Education

    Science.gov (United States)

    2012-03-01

    students  were  assigned  to  read  both  popular  and   scientific  literature  regarding  the   genetic ,  socio...Biochemistry, Soma Jobbagy, BS Biochemistry, and Erica Boetefuer, Biological Sciences Judging Rubrics for the ASBMB Undergraduate Poster Competition 2007...Bruce Boman, Biological Sciences Role of miRNAs in Regulating Colon Cancer Stem Cells 37) Carrie Barnum and Jennifer Sabatino, Genetics Zohra Ali-Khan

  1. Enhancing Air Interdiction of WMD

    Science.gov (United States)

    2014-04-01

    The Convention on International Civil Aviation, 9th ed., 9 and 10 and Jennifer K. Elsa , Weapons of Mass Destruction Counterproliferation: Legal...Issues for Ships and Aircraft, CRS Report RL32097, (Washington D.C: CRS, 1 October 2003), 24. 15 Elsa , Weapons of Mass Destruction Counterproliferation...Legal Issues for Ships and Aircraft, 20. 16 The Convention on International Civil Aviation, 9th ed., 4. 17 Elsa , Weapons of Mass Destruction

  2. Phase 2 Clinical Trials: D-Methionine to Reduce Noise-Induced Hearing Loss

    Science.gov (United States)

    2016-07-01

    Pharmaceuticals: Task completed. KP Pharmaceutical Technology, Indianapolis , Indiana is the drug manufacturer for this clinical trial. e. FDA/Regulatory...and Open House at Fort Jackson. j. June 8-9: Dr. Campbell interviewed with the Wall Street Journal at Fort Jackson. k. June 10-11, 2015: Dr...recommended by DoD Operational Medicine, Dr. Campbell, in conjunction with her business partner Jennifer Seibert, started a new biotech company, MetArmor

  3. Increasing Uncertainty: The Dangers of Relying on Conventional Forces for Nuclear Deterrence

    Science.gov (United States)

    2016-03-14

    72 | Air & Space Power Journal Increasing Uncertainty The Dangers of Relying on Conventional Forces for Nuclear Deterrence Jennifer Bradley To put...relationships and should serve as the cornerstone of US nuclear deterrence policy. Although Russia and China are not identified as adversaries of...exactly what has happened over the past year. The US decision to meet the needs of deterrence by relying less on nuclear weapons and instead devel- oping

  4. Ambient Noise Analysis from Selected CTBTO (Comprehensive Test Ban Treaty Organization) Sites

    Science.gov (United States)

    2015-02-11

    depending on location) up to 10+ years. The sites are under the National control of the countries Australia, Canada, Chile, France, Mexico , Portugal, UK...Canada HA03 Juan Fernandez Island Chile HA04 Crozet Islands France HA05 Guadeloupe France Co HA06 Socorro Island Mexico HA07 Flores Portugal...addition, Jennifer Miksis-Olds, an ARL colleague, has independentiy, via an ONR TYP, been working with Division 322, Marine Mammals & Biology

  5. Comparison of BG-Sentinel Trap and Oviposition Cups for Aedes aegypti and Aedes albopictus Surveillance in Jacksonville, Florida, USA

    Science.gov (United States)

    2015-03-01

    COMPARISON OF BG-SENTINELH TRAP AND OVIPOSITION CUPS FOR AEDES AEGYPTI AND AEDES ALBOPICTUS SURVEILLANCE IN JACKSONVILLE, FLORIDA, USA JENNIFER A...trap and oviposition cups (OCs) have both proven effective in the surveillance of Aedes species. This study aimed to determine which of the 2 traps could...best characterize the relative population sizes of Aedes albopictus and Aedes aegypti in an urban section of Jacksonville, FL. Until 1986, Ae

  6. Killing Barney Fife: Law Enforcements Socially Constructed Perception of Violence and its Influence on Police Militarization

    Science.gov (United States)

    2015-09-01

    Ethnic Group Membership and Community Efficacy,” Crime & Delinquency 49, no. 4 (October 1, 2003): 2, doi:10.1177/0011128703254418. 164 Randall Monger...and Community Efficacy.” Crime & Delinquency 49, no. 4 (October 1, 2003): 564–80. doi:10.1177/00111 28703254418. Doyle, Charles, and Jennifer Elsea...militarization reform without a clear understanding of the issue could negatively impact law enforcement’s ability to respond to emerging threats from

  7. Clinical features, predictive correlates, and pathophysiology of immune-related adverse events in immune checkpoint inhibitor treatments in cancer: a short review

    OpenAIRE

    Yoest, Jennifer M

    2017-01-01

    Jennifer M Yoest Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA Abstract: Identification and characterization of T-cell regulatory mechanisms, or checkpoints, have led to a wave of drug development aimed at inhibiting these targets to “remove the brakes” of the immune system. This class of anticancer therapeutics, termed immune checkpoint inhibitors (ICIs), has harnessed the potential of the body’s own immune system to reco...

  8. Instances of Use of United States Armed Forces Abroad, 1798-2014

    Science.gov (United States)

    2014-09-15

    Garcia, and Thomas J. Nicola . Instances of Use of United States Armed Forces Abroad, 1798-2014 Congressional Research Service Contents...landing zones near the U.S. Embassy in Saigon and the Tan Son Nhut Airfield. Mayaguez incident. On May 15, 1975, President Ford reported he had ordered...Report R41989, Congressional Authority to Limit Military Operations, by Jennifer K. Elsea, Michael John Garcia and Thomas J. Nicola . CRS Report R43344

  9. Dielectric Sensing of Toxic and Explosive Chemicals via Impedance Spectroscopy and Plasmonic Resonance

    Science.gov (United States)

    2017-05-07

    who thoroughly characterized the rapid decontamination of chemical warfare agents VX, soman (GD) and distilled mustard gas (HD)18. The work shows...Joshua J. Phillips, Jennifer R. Soliz, and Adam J. Hauser, “XMCD and Impedance Analysis of Fe2O3 Nanoparticles for Explosive and Chemical Warfare ...Virender K Sharma,"Treatment of chemical warfare agents by zero-valent iron nanoparticles and ferrate (VI)/(III) composite" Journal of hazardous

  10. Storytelling as an Instructional Method: Descriptions and Research Questions

    Science.gov (United States)

    2009-01-01

    computational brain . Cambridge, MA: Bradford/ MIT Press. Cianciolo, A. T., Prevou, M., Cianciolo, D., & Morris, R. (2007). Using digital storytelling to...volume 3, no. 2 (Fall 2009) 6–23 Storytelling as an Instructional Method: Descriptions and Research Questions Dee H. Andrews, Thomas D. Hull, and...Jennifer A. Donahue Abstract This paper discusses the theoretical and empirical foundations of the use of storytelling in instruction. The defi nition

  11. Reviews of recent publications

    Directory of Open Access Journals (Sweden)

    2006-06-01

    Full Text Available Julian W. Connolly, ed. The Cambridge Companion to Nabokov . Thomas Seifrid Simon Franklin and Emma Widdis, eds. National Identity in Russian Culture: An Introduction . Keith Livers Sander L. Gilman. Franz Kafka . Esther K. Bauer Jill Robbins, ed. P/herversions: Critical Studies of Ana Rossetti . Roberta Johnson Jennifer Warburton. John Fowles: A Life in Two Worlds . John Fowles. The Journals, Vol. I . Ed. Charles Drazin Gerd Bayer

  12. Returned Diaspora and Political Leadership. The Cases of Postcommunist Latvia and Lithuania / Jennifer Skulte-Ouaiss

    Index Scriptorium Estoniae

    Skulte-Ouaiss, Jennifer

    2006-01-01

    Rahvusliku identiteedi, diasporaa kogemuste ja postkommunistliku poliitika koosmõju on keeruline protsess. Artikkel analüüsib võõrsil elanud leedulaste ja lätlaste naasmist ning asumist juhtivatele poliitilistele positsioonidele kodumaal

  13. Vernuvshajasja diaspora i polititsheskoje liderstvo v slutshaje postkommunistitsheskoi Latvii i Litvõ / Jennifer Skulte-Ouaiss

    Index Scriptorium Estoniae

    Skulte-Ouaiss, Jennifer

    2006-01-01

    Rahvusliku identiteedi, diasporaa kogemuste ja postkommunistliku poliitika koosmõju on keeruline protsess. Artikkel analüüsib võõrsil elanud leedulaste ja lätlaste naasmist ning asumist juhtivatele poliitilistele positsioonidele kodumaal

  14. Pop / Siim Nestor

    Index Scriptorium Estoniae

    Nestor, Siim, 1974-

    2008-01-01

    Heliplaatidest: Janet Jackson "Discipline", Jack Johnson "Sleep Through The Static", The Mars Volta "The Bedlam in Goliath", Christopher Clark "Turning Dragon", Erykah Badu "New Amerykah Part One (4th World War)", Nick Cave & The Bad Seeds "Dig, Lazarus, Dig!!!"

  15. Uus peaminister, uudne valitsus / Kaivo Kopli

    Index Scriptorium Estoniae

    Kopli, Kaivo

    2010-01-01

    Suurbritannia sai koalitsioonivalitsuse. Nii peaminister David Cameron kui ka asepeaminister Nick Clegg on vihjanud, et eelistavad lõdvemaid suhteid USA-ga, kui need olid Gordon Brownil ja Tony Blairil. Konservatiivide partei on skeptiline EL-i koostöö suhtes

  16. Uusi plaate

    Index Scriptorium Estoniae

    2003-01-01

    Heliplaatidest: Tom Jones "Greatest hits", Pet Shop Boys "Disco 3", Epoca De Ouro Ensemble "Cafe Brasil 2", Nick Cave and The Bad Seeds "Nocturama", Pistepirkko "The Nature of 22 Pistepirkko", Jimi Tenor "Higher Planes", "Guitars, Saxes & More", "Inspired 2"

  17. Pop / Mart Kuldkepp

    Index Scriptorium Estoniae

    Kuldkepp, Mart

    2008-01-01

    Heliplaatidest: The Wombats "A Guide to Love, Loss & Desperation", Lenny Kravitz "It is Time for a Love Revolution", Nick Cave & Warren Ellis "OST: The Assassination of Jesse James by the Coward Robert Ford", Pat Metheny "Secret Story", Lupe Fiasco "The Cool"

  18. A new protocol for extraction of C0t-1 DNA from rice

    African Journals Online (AJOL)

    USER

    2010-07-12

    Jul 12, 2010 ... plant species differentiation and genome evolution. A new protocol to ... According to nick translation theory, the genomic DNA was digested by DNase I and ... according to the formula Cot-1 = 1 = mol/L × Ts. Since highly and.

  19. Fulltext PDF

    Indian Academy of Sciences (India)

    In the first group, the paper by Nick Devereux reviews Hubble Space .... here that the STARK-B database is included in the new search facility for such data namely Virtual Atomic and Molecular Data Center (VAMDC – http://vamdc.org/).

  20. Pop & rock / Valner Valme

    Index Scriptorium Estoniae

    Valme, Valner, 1970-

    2001-01-01

    Uute heliplaatide: Nick Cave And The Bad Seeds "No More Shall We Part", Andru Donalds "Let's Talk About It", No Angels "Elle'ments", The Experimental Pop Band "The Tracksuit Trilogy", Ellen ten Damme "I Am Here", Id_Rev "Sina ei" tutvustused

  1. Plaadid / Villu Päärt

    Index Scriptorium Estoniae

    Päärt, Villu, 1972-

    2002-01-01

    Uutest plaatidest Nick Carter "Now Or Never", Brian Mcknight "From There To here 1989-2002", Rod Stuart "The Grat American Songbook", New Order "International", Justin Timberlake "Justified", Manic Street Prachers "Forever Delayed - Greatest Hits", LHB "Tell 'Em Who We Are"

  2. Äraigatsuse salakajad / Aita Kivi

    Index Scriptorium Estoniae

    Kivi, Aita, 1954-

    2001-01-01

    Sisu : Rein Põder. Hula; David Shahar. Tema majesteedi agent; Stephen Kuusisto. Pimedate planeet; Joanna Trollope. Mehed ja tütarlapsed; Detlef Jena. Venemaa tsaarinnad; Helle Helle. Maja ja kodu; Nick Hornby. Ühest poisist; Deepak Chopra. Eatu keha, ajatu vaim

  3. the efficacy of xylopia aethiopica and piper guinense seeds powder

    African Journals Online (AJOL)

    Sammy

    rice grain pests, it is essential that necessary control measures are put in place to ... Similarly, Teetes and Gilstrap (1986) were of the view that the use of chemical ... were killed, as suggested by Ivbijaro (1990) and Wee and Nick (1998).

  4. A multiverse play divides opinion

    Science.gov (United States)

    Crease, Robert P.

    2015-03-01

    The stage lights rise. A man and woman meet in a cute way - "Do you know why it's impossible to lick the tips of your elbows?" she asks - they chat momentarily, and separate. The play is Constellations by Nick Payne.

  5. Defense Institution Building in Africa: An Assessment

    Science.gov (United States)

    2016-01-01

    relevant to Africa, and 14 U.S. Department of the Army, Army Security Cooperation Handbook, Washington, D.C., Pamphlet 11-31, March 5, 2013b; Jennifer... brochure , Lackland Air Force Base, Tex.: U.S. Air Force, undated. DIB Programs in Africa: Challenges and Responses 53 human rights, stability... brochure , Lackland Air Force Base, Tex.: U.S. Air Force, undated. As of September 25, 2015: http://www.37trw.af.mil/shared/media/document/AFD

  6. Psychiatric comorbidities in a young man with subacute myelopathy induced by abusive nitrous oxide consumption: a case report

    OpenAIRE

    Mancke, Falk; Kaklauskait?, Gintar?; Kollmer, Jennifer; Weiler, Markus

    2016-01-01

    Falk Mancke,1,2,* Gintare Kaklauskaite,1,* Jennifer Kollmer,3 Markus Weiler1 1Department of Neurology, 2Department of General Psychiatry, Center for Psychosocial Medicine, 3Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany *These authors contributed equally to this work Abstract: Nitrous oxide (N2O), a long-standing anesthetic, is known for its recreational use, and its consumption is on the rise. Several case studies have reported neurological and psychiatric ...

  7. What Polar Bears Can Teach Us about Mission Creep

    Science.gov (United States)

    2015-04-16

    directors in November 1917.8 Czech legionnaires, who needed to secure an evacuation route, quickly 6 Margaret McMillian, Paris 1919 – Six months...sign Treaty of Brest -Litovsk with Germans 26 March Bolsheviks agree to permit Czechs to return to Europe via Vladivostok 30 March Reports on German... Paris 1919 – Six months that changed the world. New York: Random House, 2003. Moroney, Jennifer D.P., Beth Grill, Joe Hagler, Lianne Kennedy

  8. Mathematics Teacher Identity in the Context of Mathematics Reform: Elementary Teacher Experiences

    OpenAIRE

    Sun, Jennifer

    2017-01-01

    ABSTRACT OF THE DISSERTATIONMathematics Teacher Identity in the Context of Mathematics Reform:Elementary Teacher Experiences ByJennifer SunDoctor of Philosophy in EducationUniversity of California, Irvine, 2017Associate Professor Elizabeth A. van Es, ChairReform efforts and changes in mathematics education have brought on a shift towards a new vision of mathematics teaching in the United States. In light of recent accountability standards, the focus on teacher learning within the context of m...

  9. Cooperative Search with Autonomous Vehicles in a 3D Aquatic Testbed

    Science.gov (United States)

    2012-01-01

    Cooperative Search with Autonomous Vehicles in a 3D Aquatic Testbed Matthew Keeter1, Daniel Moore2,3, Ryan Muller2,3, Eric Nieters1, Jennifer...Many applications for autonomous vehicles involve three-dimensional domains, notably aerial and aquatic environments. Such applications include mon...TYPE 3. DATES COVERED 00-00-2012 to 00-00-2012 4. TITLE AND SUBTITLE Cooperative Search With Autonomous Vehicles In A 3D Aquatic Testbed 5a

  10. Blatt v. Cabela's Retail, Inc. and a New Path for Transgender Rights

    OpenAIRE

    Levi, Jennifer; Barry, Kevin

    2018-01-01

    Published: Kevin Barry & Jennifer Levi, Blatt v. Cabela's Retail, Inc. and a New Path for Transgender Rights, 127 YALE L.J. F. 373 (2017). Since the Supreme Court recognized marriage equality in Obergefell v. Hodges, civil rights advocates have increasingly set their sights on transgender rights as the next legal frontier. Sex discrimination law, though an essential statutory tool, is not the only potential avenue for securing rights for transgender individuals. Another important federal ...

  11. Justice in the Air: Tracking Toxic Pollution from America's Industries and Companies to Our States, Cities, and Neighborhoods

    OpenAIRE

    Michael Ash; James Boyce; Grace Chang; Justin Scoggins; Manuel Pastor

    2009-01-01

    This new environmental justice study, (co-authored by PERI’s James Boyce, Michael Ash, & Grace Chang, along with Manuel Pastor, Justin Scoggins, & Jennifer Tran of the Program for Environmental and Regional Equity at the University of Southern California) examines not only who receives the disproportionate share of toxic air releases -- low-income communities and people of color -- but who is releasing them. Justice in the Air: Tracking Toxic Pollution from America's Industries and Companies ...

  12. Collaborative Research to Optimize Warfighter Nutrition II (CROWN II)

    Science.gov (United States)

    2016-09-01

    Serum 500 Cytokines X X X Serum 500 Cortisol X X X Serum 1000 C-Reactive Protein X X X Serum DHEA-S1 X X X Serum Growth hormone X...assays were completed and include the following: cortisol, DHEAs, growth hormone , glucose, hsCRP, IGF-1, IL-6, insulin, LH, prolactin, SHBG...severe energy deficit and recovery: a randomized, placebo controlled trial. PI: Jennifer Rood USARIEM led projects 3. PBRC IRB # 2016-003

  13. Book Reviews

    OpenAIRE

    Redactie KITLV

    2008-01-01

    Trevor Wilson (ed.); Myanmar’s long road to national reconciliation (Jean A. Berley) Jennifer Lindsay (ed.); Between tongues; Translation and/of/in performance in Asia (Michael Bodden) Volker Grabowsky; Bevölkerung und Staat in Lan Na; Ein Beitrag zur Bevölkerungsgeschichte Südostasiens Peter Boomgaard) Odille Gannier, Cécile Picquoin (eds); Journal de bord d’Etienne Marchand; Le voyage du Solide autour du monde (1790-1792 (H.J.M. Claessen) Arjan va...

  14. Performance of the Quidel Sofia Rapid Influenza Diagnostic Test During the 2012-2013 and 2013-2014 Influenza Seasons

    Science.gov (United States)

    2016-03-23

    Performance of the Quidel Sofia rapid influenza diagnostic test during the 2012–2013 and 2013–2014 influenza seasons Peter E. Kammerer, Jennifer M... Influenza A+B Fluorescent Immunoassay was used to test nasal swab specimens from patients with influenza -like illness at US–Mexico border-area clinics in...the 2012–2013 and 2013–2014 influenza seasons. Compared with real-time reverse transcription polymerase chain reaction, the overall sensitivities and

  15. 76 FR 73608 - Reliability Technical Conference, North American Electric Reliability Corporation, Public Service...

    Science.gov (United States)

    2011-11-29

    ... or municipal authority play in forming your bulk power system reliability plans? b. Do you support..., North American Electric Reliability Corporation (NERC) Nick Akins, CEO of American Electric Power (AEP..., EL11-62-000] Reliability Technical Conference, North American Electric Reliability Corporation, Public...

  16. Wallace ja Gromit tegid Hollywoodis puhta töö / Andris Feldmanis

    Index Scriptorium Estoniae

    Feldmanis, Andris, 1982-

    2006-01-01

    Hollywoodi animafilmide Annie-auhindade jagamisel võitis 9 auhinda täispikk animafilm "Wallace ja Gromit : Libaküüliku needus" ("Wallace & Gromit : The Curse of the Were-Rabbit") : režissöörid Nick Park ja Steve Box : Suurbritannia 2005

  17. Plasmid DNA damage caused by stibine and trimethylstibine

    International Nuclear Information System (INIS)

    Andrewes, Paul; Kitchin, Kirk T.; Wallace, Kathleen

    2004-01-01

    Antimony is classified as 'possibly carcinogenic to humans' and there is also sufficient evidence for antimony carcinogenicity in experimental animals. Stibine is a volatile inorganic antimony compound to which humans can be exposed in occupational settings (e.g., lead-acid battery charging). Because it is highly toxic, stibine is considered a significant health risk; however, its genotoxicity has received little attention. For the work reported here, stibine was generated by sodium borohydride reduction of potassium antimony tartrate. Trimethylstibine is a volatile organometallic antimony compound found commonly in landfill and sewage fermentation gases at concentrations ranging between 0.1 and 100 μg/m 3 . Trimethylstibine is generally considered to pose little environmental or health risk. In the work reported here, trimethylstibine was generated by reduction of trimethylantimony dichloride using either sodium borohydride or the thiol compounds, dithioerythritol (DTE), L-cysteine, and glutathione. Here we report the evaluation of the in vitro genotoxicities of five antimony compounds--potassium antimony tartrate, stibine, potassium hexahydroxyantimonate, trimethylantimony dichloride, and trimethylstibine--using a plasmid DNA-nicking assay. Of these five antimony compounds, only stibine and trimethylstibine were genotoxic (significant nicking to pBR 322 plasmid DNA). We found stibine and trimethylstibine to be about equipotent with trimethylarsine using this plasmid DNA-nicking assay. Reaction of trimethylantimony dichloride with either glutathione or L-cysteine to produce DNA-damaging trimethylstibine was observed with a trimethylantimony dichloride concentration as low as 50 μM and L-cysteine or glutathione concentrations as low as 500 and 200 μM, respectively, for a 24 h incubation

  18. Dynamics and Stability of Rolling Viscoelastic Tires

    Energy Technology Data Exchange (ETDEWEB)

    Potter, Trevor [Univ. of California, Berkeley, CA (United States)

    2013-04-30

    Current steady state rolling tire calculations often do not include treads because treads destroy the rotational symmetry of the tire. We describe two methodologies to compute time periodic solutions of a two-dimensional viscoelastic tire with treads: solving a minimization problem and solving a system of equations. We also expand on work by Oden and Lin on free spinning rolling elastic tires in which they disovered a hierachy of N-peak steady state standing wave solutions. In addition to discovering a two-dimensional hierarchy of standing wave solutions that includes their N-peak hiearchy, we consider the eects of viscoelasticity on the standing wave solutions. Finally, a commonplace model of viscoelasticity used in our numerical experiments led to non-physical elastic energy growth for large tire speeds. We show that a viscoelastic model of Govindjee and Reese remedies the problem.

  19. Turism rikastab : rahvusvaheline turismikonverents

    Index Scriptorium Estoniae

    2006-01-01

    28. septembril toimus Tallinnas Rahvusraamatukogus rahvusvaheline turismikonverents"Turism rikastab". Ülevaade majandus- ja kommunikatsiooniministeeriumi majandusarengu asekantsleri Maria Värtoni, Graham Mckenzie, Linnar Viigi, Nick Skelloni, Mario Ascencao (Haagi ülikool), David Carsoni (Ulsteri ülikool), Vesa Heikkineni ja Imre Sooääre ettekannetest

  20. Moskvas hoitav Adolf Hitleri kolbatükk ei kuulu füürerile / Aadu Hiietamm

    Index Scriptorium Estoniae

    Hiietamm, Aadu, 1954-

    2009-01-01

    USA arheoloogi Nick Bellantoni avastus, et Moskvas hoitav Adolf Hitleri kuuliauguga koljutükk ei kuulugi füürerile, annab tõenäoliselt uut hoogu vandenõuteoreetikutele, kes usuvad, et Hitler ei teinud 1945. aastal enesetappu, vaid põgenes välismaale

  1. DNA expressions - A formal notation for DNA

    NARCIS (Netherlands)

    Vliet, Rudy van

    2015-01-01

    We describe a formal notation for DNA molecules that may contain nicks and gaps. The resulting DNA expressions denote formal DNA molecules. Different DNA expressions may denote the same molecule. Such DNA expressions are called equivalent. We examine which DNA expressions are minimal, which

  2. Recent Naval Postgraduate School Publications

    Science.gov (United States)

    1988-09-30

    pay, performance ratings and voluntary separations 12th Annual Convention, Eastern Econ. Asso., Philadelphia, PA, Apr., 1986. Sol nick, L M...ilow above the Marine boundary layer 4th Conference Meteorol. and Oceano . Coastal Zone, Anaheim, CA., February, 3-5, 1988. Smith, R Computational

  3. Employment Relations in Denmark

    DEFF Research Database (Denmark)

    Madsen, Jørgen Steen; Due, Jesper Jørgen; Andersen, Søren Kaj

    2011-01-01

    Jørgen Steen Madsen, Jesper Due og Søren Kaj Andersen har skrevet et kapitel om udviklingen i dansk arbejdsmarkedsregulering til bogen International and Comparative Employment Relations, redigeret af Greg Bamber, Russell Lansbury og Nick Wailes. Bogen indeholder bidrag, der præsenterer og...

  4. The Guatemalan Military: Transition from War to Peace

    Science.gov (United States)

    2001-06-01

    1992. Cerdas Cruz, Rodolfo. El Precio de Una Herencia. Fuerza Armadas, Democracia y Derechos Humanos en Centroamérica. San José: Instituto...Interamericano de Derechos Humanos , 1996. Cullather, Nick. Secret History, The CIA’s Classified Account of Its Operations in Guatemala, 1952-1954. Stanford

  5. Retention, Incentives, and DoD Experience Under the 40-Year Military Pay Table

    Science.gov (United States)

    2016-01-01

    Beth J. Asch, James Hosek, Jennifer Kavanagh, Michael G. Mattock Retention, Incentives, and DoD Experience Under the 40-Year Military Pay Table C O...Authorization Act (NDAA) directed the Secretary of Defense to review the military’s pay tables, focusing on whether the 40-year pay table is still justified as...a retention tool. Congress extended the pay tables to 40 years as part of the fiscal year 2007 NDAA to pro- vide an incentive for the most

  6. Successful Separationists in a Unity Fan Society: Al-Hirak Al-Janubi Social Movement in the Republic of Yemen

    Science.gov (United States)

    2013-12-01

    Al-Janubi’s popularity and motivations. Jennifer Earl uses three key typology dimensions to categorize repression of a given movement. Those...use Earl’s typology of repression as an attempt to understand the effects on the relationship between the government and Al-Hirak Al-Janubi in Yemen...let him invest in Aden; then he would sell him the sea area to dump rocks onto it to make it suitable as a tourist site. Finally, he would sell him

  7. Alternatives to Autograft Evaluated in a Rabbit Segmental Bone Defect

    Science.gov (United States)

    2015-07-09

    mesenchymal stem cells for off-the-shelf bone tissue engineering application. Biomaterials 33(9):2656–2672. doi:10.1016/j.biomaterials.2011.12.025 14...segmental bone defects in the rabbit with vascularized tissue engineered bone . Biomaterials 31(6):1171– 1179. doi:10.1016/j.biomaterials.2009.10.043 International Orthopaedics (SICOT) ...ORIGINAL PAPER Alternatives to autograft evaluated in a rabbit segmental bone defect Jennifer S. McDaniel1 & Marcello Pilia1 & Vivek Raut2 & Jeffrey

  8. Sound / Märt Milter

    Index Scriptorium Estoniae

    Milter, Märt

    1998-01-01

    Uutest plaatidest Gary Moore "Out In The Fields", Pete Rock "Soul Survivor", Brand Nubian "Foundation", OST "Fear And Loathing In Las Vegas", "FFRR Classics 1988-1998",OST "Saving Private Ryan", John Lennon "Anthology", "Red, Hot + Rhapsody", Karl Jenkins/Adiemus III "Dances Of Time", Five Fifteen "Six Dimensions Of The Electric Camembert", Bruce Hornsby "Spirit Trail", Dune & London Session Orchestra "Forever And Ever", Redman "Docs Da Name 2000", Jennifer Rush "Classics", Ice Cube "War & Peace vol.1"

  9. Beware: It’s Mosquito Season (A Cup of Health with CDC)

    Centers for Disease Control (CDC) Podcasts

    2013-06-27

    West Nile virus and other arboviruses are transmitted primarily through the bite of an infected mosquito or tick. These viruses cause thousands of people to get sick each summer. In 2012, there was a substantial increase in the number of West Nile virus cases reported in the U.S. In this podcast, Jennifer Lehman discusses ways to avoid being infected with an arbovirus.  Created: 6/27/2013 by MMWR.   Date Released: 6/27/2013.

  10. State of Flood Related Modeling Along Middle Rio Grande: Report Documentary 2007-2008 Work

    Science.gov (United States)

    2010-07-01

    Bosque Environment (CBE) Title Prepared By Rio Grande Silvery Minnow Sanctuary Proposed Site, 1-D HEC - RAS Model of Area of Interest Jonathan Acbuchon...Erosion Jennifer G. Duan Case Study: Application of the HEC -6 Model for the Main Stem of the Kankakee River in Illinois Nani G. Bhowmik, D.WRE...1 bank-attached bar HYDRAULIC ANALYSIS One-dimensional HEC - RAS models – Fixed-bed analysis – Calibrated to gauged flow at time of survey and 2005

  11. On lying and deceiving.

    OpenAIRE

    Bakhurst, D

    1992-01-01

    This article challenges Jennifer Jackson's recent defence of doctors' rights to deceive patients. Jackson maintains there is a general moral difference between lying and intentional deception: while doctors have a prima facie duty not to lie, there is no such obligation to avoid deception. This paper argues 1) that an examination of cases shows that lying and deception are often morally equivalent, and 2) that Jackson's position is premised on a species of moral functionalism that misconstrue...

  12. Climate Change, State Stability, and Political Risk in Africa

    Science.gov (United States)

    2016-09-30

    www.acq.osd.mil/dsb/reports/ADA552760.pdf. iii P.P. Hearn Jr. et al., “Global GIS Database; Digital Atlas of Africa,” USGS Numbered Series, Data...Series, (2001), http://pubs.er.usgs.gov/publication/ds62B. iv U.S. Geological Survey World Conventional Resources Assessment Team, “USGS Digital ...Retrenchment and the Exercise of Citizenship in Africa,” Comparative Political Studies 44, 9 (2011): 1238-1266; Jennifer N. Brass, “Blurring Boundaries

  13. BOLD magnetic resonance imaging in nephrology

    OpenAIRE

    Hall ME; Jordan JH; Juncos LA; Hundley WG; Hall JE

    2018-01-01

    Michael E Hall,1,2 Jennifer H Jordan,3 Luis A Juncos,1,2 W Gregory Hundley,3 John E Hall2 1Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA; 2Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA; 3Department of Internal Medicine, Section on Cardiovascular Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA Abstract: Magnetic resonance (MR) imaging, a non-invasive modality that provides ana...

  14. Ethnoburb versus Chinatown : Two Types of Urban Ethnic Communities in Los Angeles

    Directory of Open Access Journals (Sweden)

    Li Wei

    1998-12-01

    Full Text Available I am truly grateful to Jennifer Wolch who provided substantive critiques on the paper ; organizers and participants of the "Symposium on Cultural Approaches in Geography" who provided opportunities for me to present an earlier version of this paper ; Chris Seidel who offered editorial assistance ; and all those who participated the Chinatown surveys and whom I interviewed. Ethnic settlement patterns and their relationships with ethnic identity have long been important issues for ethnic studie...

  15. Nutrition guidelines for undergraduate medical curricula: a six-country comparison

    OpenAIRE

    Crowley, Jennifer; Ball, Lauren; Laur, Celia; Wall, Clare; Arroll, Bruce; Poole, Phillippa; Ray, Sumantra

    2015-01-01

    Jennifer Crowley,1 Lauren Ball,2 Celia Laur,3 Clare Wall,1 Bruce Arroll,4 Phillippa Poole,5 Sumantra Ray3 1Discipline of Nutrition, School of Medical Sciences, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand; 2Centre for Health Practice Innovation, Griffith University, Gold Coast, QLD, Australia; 3Need for Nutrition Education/Innovation Programme, Medical Research Council Human Nutrition Research, Cambridge, UK; 4Department of General Practice and Pri...

  16. The Myth of Religious Experience Revisited

    Directory of Open Access Journals (Sweden)

    Zangwill Nick

    2017-10-01

    Full Text Available This article replies to Manuel Fasko’s “The Demystification of Nick Zangwill’s ‘Myth of Religious Experience’” (2017, showing how author’s argument against the possibility of religious experience presented in “The Myth of Religious Experience” (2004 remains in tact.

  17. Limited numbers of apoptotic cells in fresh paraffin embedded bone marrow samples of patients with myelodysplastic syndrome

    NARCIS (Netherlands)

    Brada, SJL; van de Loosdrecht, AA; Koudstaal, J; de Wolf, JTM; Vellenga, E

    In myelodysplasia (MDS) the precise mechanism of ineffective erythropoiesis is not fully elucidated, but it is suggested that apoptosis may contribute to this process. We performed TdT-mediated dUTP-nick end labelling (TUNEL) staining of paraffin embedded bone marrow specimens to assess the amount

  18. 76 FR 36903 - Privacy Act of 1974; System of Records

    Science.gov (United States)

    2011-06-23

    ... have a need-to-know. Individuals responsible for servicing the records in the performance of official... name, nick names, Social Security Number (SSN), gender, date of birth, personal cell phone number, home... address: Delete entry and replace with ``Automated Civil Engineer System/ Interim Work Management System...

  19. Berlinale terad / Kadri Kõusaar

    Index Scriptorium Estoniae

    Kõusaar, Kadri

    2006-01-01

    56. Berliini festivali filme - Jasmila Zhbanici "Grbavica", Michael Winterbottomi, Mat Whitecrossi "Teekond Guantanamosse", tailase Pen-ek Ratanaruangi "Nähtamatud lained", John Hillcoati "Ettepanek" (stsenarist ja muusika autor Nick Cave), Bennett Milleri "Capote" (nimiosas P.S. Hoffman), Yang Yong-hi dokfilm "Kallis Pyongyang", Tomer Heymanni dokfilm "Pabernukud"

  20. The good, the bad, and the voter: the impact of hate speech prosecution of a politician on the electoral support for his party

    NARCIS (Netherlands)

    van Spanje, J.; de Vreese, C.

    2015-01-01

    Hate speech prosecution of politicians is a common phenomenon in established democracies. Examples of politicians tried for hate speech include Nick Griffin in Britain and Jean-Marie Le Pen in France. Does hate speech prosecution of politicians affect the electoral support for their party? This is

  1. Zarqawi’s Sfumato: Operational Art in Irregular Warfare

    Science.gov (United States)

    2013-05-23

    in Baghdad and Karbala during the Shia festival of Ashura in March of 2004.80 These attacks were preceded by the bombing of the Jordanian embassy...American contractors Nick Berg and Eugene Armstrong. Zarqawi released edited videos with music and logos detailing multiple suicide bombings against

  2. Physical association of pyrimidine dimer DNA glycosylase and apurinic/apyrimidinic DNA endonuclease essential for repair of ultraviolet-damaged DNA

    International Nuclear Information System (INIS)

    Nakabeppu, Y.; Sekiguchi, M.

    1981-01-01

    T4 endonuclease, which is involved in repair of uv-damaged DNA, has been purified to apparent physical homogeneity. Incubation of uv-irradiated poly(dA).poly(dT) with the purified enzyme preparations resulted in production of alkali-labile apyrimidinic sites, followed by formation of nicks in the polymer. By performing a limited reaction with T4 endonuclease V at pH 8.5, irradiated polymer was converted to an intermediate form that carried a large number of alkali-labile sites but only a few nicks. The intermediate was used as substrate for the assay of apurinic/apyrimidinic DNA endonuclease activity. The two activities, a pyrimidine dimer DNA glycosylase and an apurinic/apyrimidinic DNA endonuclease, were copurified and found in enzyme preparations that contained only a 16,000-dalton polypeptide. These results strongly suggested that a DNA glycosylase specific for pyrimidine dimers and an apurinic/apyrimidinic DNA endonuclease reside in a single polypeptide chain coded by the denV gene of bacteriophage T4

  3. Children in Hot Cars Result in Fatal Consequences

    Medline Plus

    Full Text Available ... a hot vehicle. “Putting it bluntly, leaving your child in a hot car is like leaving your child in a lit oven,” said Dr. Nick Jouriles. “ ... or experience changes in your schedule or your child is in the back seat, making it more ...

  4. The Significance of Bottom in Shakespeare's A Midsummer Night's Dream

    OpenAIRE

    KREMENIK, Michael

    1999-01-01

    The importance of the character Nick Bottom in A Midsummer Night's Dream will be discussed. He is the only character able to converse with both the natural and fairy worlds in the play. This makes his character special. This article will attempt to analyze why this is so.

  5. 76 FR 56196 - Agency Information Collection Activities; Proposed Collection; Comment Request

    Science.gov (United States)

    2011-09-12

    ..., and IV); (b) the FTC's consumer complaint systems; (c) the FTC's program evaluation activities and (d... (Nick M) and Ami Dziekan (Ami D), Division of Enforcement, Bureau of Consumer Protection, Federal Trade... Commission's Rules of Practice (primarily Parts I, II, and IV); (b) the FTC's consumer complaint systems; (c...

  6. Fighting Fire with Fire

    DEFF Research Database (Denmark)

    Bossetta, Michael

    2017-01-01

    Advancing the concept of populism as a political style, this study compares the debate performances of two British party leaders, Nick Clegg and Nigel Farage, as they clashed in a pair of televised debates over Britain’s EU membership ahead of the 2014 European Parliament elections. The argument ...

  7. Uudised

    Index Scriptorium Estoniae

    2005-01-01

    Eesti artisti Pafi ehk Paavo Eensalu lugu "Daisy" ilmub septembris Nick Luscombe poolt kokkupandaval kogumikul "Flo-Motion vol 2". Popansambel Radiohead alustas oma uut LPd tehes blogi ehk internetipäeviku "Dead Air Space" pidamist, aadressilt http://www.radiohead.com/deadairspace/ võib leida bändiliikmete kirjutisi

  8. Ostrich: Journal of African Ornithology - Vol 88, No 1 (2017)

    African Journals Online (AJOL)

    DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Abdulmaula Hamza, Nicola Baccetti, Joe Sultana, Jaber Yahia, Marco Zantello, Adriano de Faveri, Nick Cutts, John Borg, Hichem Azafzaf, Pierre Defos du Rau, Esam Bourass, Khaled Etayeb, Michael Elliott, 53–58. http://dx.doi.org/10.2989/00306525.2016.1231139 ...

  9. 77 FR 8892 - Detailed Planning To Consider Additional Land Protection on the Missouri River From Fort Randall...

    Science.gov (United States)

    2012-02-15

    ... 25486, DFC, Denver, CO 80225. FOR FURTHER INFORMATION CONTACT: Nick Kaczor, Planning Team Leader... old, wider river valley contains important habitat for at least 60 native and 26 sport fish. In... historical characteristics witnessed by Lewis and Clark during their explorations in the early 1800s. The FWS...

  10. Muusika DVD-d / Priit Hõbemägi

    Index Scriptorium Estoniae

    Hõbemägi, Priit, 1957-

    2006-01-01

    Uutest DVD-dest Moody Blues "Lovely to See You - Live", Nick Cave and The Bad Seeds "Road to God Knows Wherw", Thin Lizzy "Thunder and Lightning Tour", Eels "Eels With Strings - Live at Town Hall", Moby "Live. Hotel Tour 2005", Corvus Corax "Cantus Buranus", Destiny's Child "Live in Atlanta"

  11. Characterization of the adenoassociated virus Rep protein complex formed on the viral origin of DNA replication

    International Nuclear Information System (INIS)

    Li Zengi; Brister, J. Rodney; Im, Dong-Soo; Muzyczka, Nicholas

    2003-01-01

    Interaction between the adenoassociated virus (AAV) replication proteins, Rep68 and 78, and the viral terminal repeats (TRs) is mediated by a DNA sequence termed the Rep-binding element (RBE). This element is necessary for Rep-mediated unwinding of duplex DNA substrates, directs Rep catalyzed cleavage of the AAV origin of DNA replication, and is required for viral transcription and proviral integration. Six discrete Rep complexes with the AAV TR substrates have been observed in vitro, and cross-linking studies suggest these complexes contain one to six molecules of Rep. However, the functional relationship between Rep oligomerization and biochemical activity is unclear. Here we have characterized Rep complexes that form on the AAV TR. Both Rep68 and Rep78 appear to form the same six complexes with the AAV TR, and ATP seems to stimulate formation of specific, higher order complexes. When the sizes of these Rep complexes were estimated on native polyacrylamide gels, the four slower migrating complexes were larger than predicted by an amount equivalent to one or two TRs. To resolve this discrepancy, the molar ratio of protein and DNA was calculated for the three largest complexes. Data from these experiments indicated that the larger complexes included multiple TRs in addition to multiple Rep molecules and that the Rep-to-TR ratio was approximately 2. The two largest complexes were also associated with increased Rep-mediated, origin cleavage activity. Finally, we characterized a second, Rep-mediated cleavage event that occurs adjacent to the normal nicking site, but on the opposite strand. This second site nicking event effectively results in double-stranded DNA cleavage at the normal nicking site

  12. 2009 International Year of Astronomy (IYA2009)

    Science.gov (United States)

    Wiseman, Jennifer

    2009-01-01

    400 years ago, Galileo first turned a telescope to the sky, and to honor that historic moment, 2009 has been designated the International Year of Astronomy (IYA2009). This session will feature two scientists who have used the telescope to understand our solar system and well beyond to yield fantastic new discoveries. Jennifer Wiseman will share the work she does with NASA, presenting beautiful and tantalizing images from the Hubble Space Telescope and discussing how space astronomy can inspire all ages.

  13. The Effect of Piracy on Somalia as a Failed State

    Science.gov (United States)

    2011-02-01

    the Pan -~ab task force to join the European Union (EU), NATO and CTF. On June 10, 2010, the UN Contact Group on Piracy off the Coast of Somalia...winning cooperation from local clans and business networks to provide authority and order is Mogusidshu’s best recipe for security. 103 The full U.N...21st Century Seapower. Naval War College Review 61, no. 1, (January 1): 6-19. http://www.proquest.com/ (accessed November 22, 2010). Cooke , Jennifer

  14. Border Encounters: American Cultural Politics and the U.S.-Mexico Border

    OpenAIRE

    Reimer, Jennifer Andrea

    2011-01-01

    AbstractBorder Encounters: American Cultural Politics and the U.S.-Mexico BorderbyJennifer Andrea ReimerDoctor of Philosophy in Ethnic StudiesUniversity of California, BerkeleyProfessor José David Saldívar, Co-ChairProfessor Laura E. Pérez, Co-ChairBorder Encounters: American Cultural Politics and the U.S.-Mexico Border is a transnational, interdisciplinary cultural study of the contemporary U.S.-Mexico border that argues for the critical role of the international border in the racial past, p...

  15. Effect of Prior Exposure at Elevated Temperatures on Tensile Properties and Stress-Strain Behavior of Four Non-Oxide Ceramic Matrix Composites

    Science.gov (United States)

    2015-06-18

    Ceramics, San Diego, CA, manufactured the SiC/SiNC and C/SiC composites using polymer infiltration and pyrolysis (PIP). The C/HYPR-SiC™ and SiC/HYPR- SiC...research. Thank you to Dr. Kristin Keller (AFRL/RXCCM), Ms. Jennifer Pierce (AFRL/RXCM), Mr. Randall Corns (AFRL/RXCCM), and Dr. Kathleen Shugart (AFRL...with Hi-Nicalon™ SiC fibers in a SiNC matrix derived by polymer infiltration and pyrolysis (PIP) (manufactured by COI Ceramics, San Diego, CA

  16. Parental risk factors for the development of pediatric acute and chronic postsurgical pain: a longitudinal study

    OpenAIRE

    Pagé, Gabrielle; Campbell,Fiona; Isaac,Lisa; Stinson,Jennifer; Katz,Joel

    2013-01-01

    M Gabrielle Pagé,1 Fiona Campbell,2,3 Lisa Isaac,2,3 Jennifer Stinson,2,4 Joel Katz1,3,5 1Department of Psychology, Faculty of Health, York University, Toronto, ON, Canada; 2Department of Anesthesia and Pain Medicine, Hospital for Sick Children, Toronto, ON, Canada; 3Department of Anesthesia, Faculty of Medicine, University of Toronto, Toronto, ON, Canada; 4Lawrence S Bloomberg Faculty of Nursing, University of Toronto, Toronto, ON, Canada; 5Department of Psychology, Hospital for S...

  17. Book Review of Love Story Written by Erich Segal

    OpenAIRE

    Handayani, Candra

    2015-01-01

    In this study, the writer will analyze the novel Love Story by Erich Segal by using the intrinsic theories. The purposes of this study are to analyze the main characters and toreveal the strengths and the weaknesses of Erich Segal‟s Love Story. Love Story tells aromantic story of two main characters, Oliver Barret IV and Jennifer Cavileri who arefrom different social and culture background. Although Love Story has some weaknesses,the strengths of this novel make it still be recommended to be ...

  18. Naval Station Guantanamo Bay: History and Legal Issues Regarding Its Lease Agreements

    Science.gov (United States)

    2016-11-17

    Jennifer K. Elsea. 4 Information on the Office of Military Commissions may be found online at http://www.mc.mil/ABOUTUS.aspx. Naval Station Guantanamo...abrogated and replaced with a new friendship treaty, the 1934 Treaty of Relations. 10 The Senate gave its advice and consent without condition on May 31... online at http://avalon.law.yale.edu/20th_century/dip_cuba002.asp. 8 U.S.-Cuba Treaty, 33 Stat. 2248. Ratifications were exchanged in July 1904. 9

  19. The rules of the game

    Science.gov (United States)

    Tay, Lee Yong; Lim, Cher Ping

    2012-12-01

    This response to Rachel Muehrer, Jennifer Jenson, Jeremy Friedberg and Nicole Husain's paper, Challenges and opportunities: Using a science- based video game in secondary school settings, explores the issues encountered while a science-based video game is introduced in secondary school settings. It highlights the importance of the context, the availability of technologies, the skilfulness of the teachers and readiness of the students for a more successful use of games in schools. In addition, the definition of student engagement is also further discussed.

  20. Narrative Strategien in der TV-Serie Desperate Housewives

    OpenAIRE

    Fuchs, Marion

    2005-01-01

    The TV-series Desperate Housewives is desperately loved by fans and desperately hated by critics. American columnist Jennifer L. Pozner accuses the series of portraying every female character as incompetent, in her opinion that is "just good old fashioned Hollywood crap." But why is this "Hollywood crap" so astonishingly successful (25 million viewers in the US, 3 million viewers in Germany) and who is the typical viewer? Why is the (dead) narrator so important and does the TV-Series really r...