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Sample records for newly developing field

  1. Newly velocity field of Sulawesi Island from GPS observation

    Science.gov (United States)

    Sarsito, D. A.; Susilo, Simons, W. J. F.; Abidin, H. Z.; Sapiie, B.; Triyoso, W.; Andreas, H.

    2017-07-01

    Sulawesi microplate Island is located at famous triple junction area of the Eurasian, India-Australian, and Philippine Sea plates. Under the influence of the northward moving Australian plate and the westward motion of the Philippine plate, the island at Eastern part of Indonesia is collide and with the Eurasian plate and Sunda Block. Those recent microplate tectonic motions can be quantitatively determine by GNSS-GPS measurement. We use combine GNSS-GPS observation types (campaign type and continuous type) from 1997 to 2015 to derive newly velocity field of the area. Several strategies are applied and tested to get the optimum result, and finally we choose regional strategy to reduce error propagation contribution from global multi baseline processing using GAMIT/GLOBK 10.5. Velocity field are analyzed in global reference frame ITRF 2008 and local reference frame by fixing with respect alternatively to Eurasian plate - Sunda block, India-Australian plate and Philippine Sea plates. Newly results show dense distribution of velocity field. This information is useful for tectonic deformation studying in geospatial era.

  2. A newly developed snack effective for enhancing bone volume

    Directory of Open Access Journals (Sweden)

    Hayashi Hidetaka

    2009-07-01

    Full Text Available Abstract Background The incidence of primary osteoporosis is higher in Japan than in USA and European countries. Recently, the importance of preventive medicine has been gradually recognized in the field of orthopaedic surgery with a concept that peak bone mass should be increased in childhood as much as possible for the prevention of osteoporosis. Under such background, we have developed a new bean snack with an aim to improve bone volume loss. In this study, we examined the effects of a newly developed snack on bone volume and density in osteoporosis model mice. Methods Orchiectomy (ORX and ovariectomy (OVX were performed for C57BL/6J mice of twelve-week-old (Jackson Laboratory, Bar Harbar, ME, USA were used in this experiment. We prepared and given three types of powder diet e.g.: normal calcium diet (NCD, Ca: 0.9%, Clea Japan Co., Tokyo, Japan, low calcium diet (LCD, Ca: 0.63%, Clea Japan Co., and special diet (SCD, Ca: 0.9%. Eighteen weeks after surgery, all the animals were sacrified and prepared for histomorphometric analysis to quantify bone density and bone mineral content. Results As a result of histomorphometric examination, SCD was revealed to enhance bone volume irrespective of age and sex. The bone density was increased significantly in osteoporosis model mice fed the newly developmental snack as compared with the control mice. The bone mineral content was also enhanced significantly. These phenomena were revealed in both sexes. Conclusion It is shown that the newly developed bean snack is highly effective for the improvement of bone volume loss irrespective of sex. We demonstrated that newly developmental snack supplements may be a useful preventive measure for Japanese whose bone mineral density values are less than the ideal condition.

  3. Field studies into the dynamics of product development tasks

    NARCIS (Netherlands)

    Oorschot, van K.E.; Bertrand, J.W.M.; Rutte, C.G.

    2005-01-01

    Purpose – This paper aims to describe three exploratory field studies investigating which characteristics add to later time to market and/or low product functionality of newly developed products. The studies are conducted at the level of developments tasks, or work packages. The first and second

  4. Sizing Performance of the Newly Developed Eddy Current System

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Chan Hee; Lee, Hee Jong; Yoo, Hyun Ju; Moon, Gyoon Young; Lee, Tae Hoon [Korea Hydro and Nuclear Power Co., Ltd., Daejeon (Korea, Republic of)

    2013-10-15

    This paper describes the comparison results of sizing performance for two systems. The KHNP developed a new eddy current testing system for the inspection of steam generator tubing in domestic nuclear power plants. The equivalency assessment of the newly developed system with the EPRI-qualified system was already carried out. In this paper, the comparisons of depth-sizing performance for the artificial flaws between two systems were performed. The results show that the newly developed system is in good agreement with the qualified system. Therefore, it is expected that the newly developed eddy current system can be used for the inspection of steam generator tubing in nuclear power plants. There are some non-destructive examination (NDE) methods for the inspection of components in nuclear power plants, such as ultrasonic, radiographic, eddy current testing, etc. The eddy current testing is widely used for the inspection of steam generator (SG) tubing because it offers a relatively low cost approach for high speed, large scale testing of metallic materials in high pressure and temperature engineering systems. The Korea Hydro and Nuclear Power Co., Ltd. (KHNP) developed an eddy current testing system for the inspection of steam generator tubing in nuclear power plants. This system includes not only hardware but software such as the frequency generator and data acquisition-analysis program. The foreign eddy current system developed by ZETEC is currently used for the inspection of steam generator tubing in domestic nuclear power plants. The equivalency assessment between two systems was already carried out in accordance with the EPRI steam generator examination guidelines.

  5. Design of an X-band accelerating structure using a newly developed structural optimization procedure

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Xiaoxia [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Fang, Wencheng; Gu, Qiang [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800 (China); Zhao, Zhentang, E-mail: zhaozhentang@sinap.ac.cn [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800 (China); University of Chinese Academy of Sciences, Beijing 100049 (China)

    2017-05-11

    An X-band high gradient accelerating structure is a challenging technology for implementation in advanced electron linear accelerator facilities. The present work discusses the design of an X-band accelerating structure for dedicated application to a compact hard X-ray free electron laser facility at the Shanghai Institute of Applied Physics, and numerous design optimizations are conducted with consideration for radio frequency (RF) breakdown, RF efficiency, short-range wakefields, and dipole/quadrupole field modes, to ensure good beam quality and a high accelerating gradient. The designed X-band accelerating structure is a constant gradient structure with a 4π/5 operating mode and input and output dual-feed couplers in a racetrack shape. The design process employs a newly developed effective optimization procedure for optimization of the X-band accelerating structure. In addition, the specific design of couplers providing high beam quality by eliminating dipole field components and reducing quadrupole field components is discussed in detail.

  6. Characteristics and land suitability of newly establish rice field in Lesung Batu Muda, Rawas Ulu, Musi Rawas, South Sumatera

    Directory of Open Access Journals (Sweden)

    R Sudaryanto

    2015-04-01

    Full Text Available Rice field has a strategic function because it is the main provider of food for the population of Indonesia. The data of the land use for the rice field in Indonesia showed that around 41% in Java Island. Agricultural technology at the level of industry experienced rapid progress, but the technology implementation at the level by farmer is relatively slow. Increased production of rice in Indonesia was reported of less than 1% per year. The research aimed to study the characteristics and land suitability of newly established rice field in Lesung Batu Muda, Rawas Ulu, Musi Rawas, South Sumatera. There were two soil land units that were tested included water availability, rooting medium, level of erosion, soil chemical properties and land preparation. The results of the study showed that newly established rice fields in Lesung Batu Muda, Rawas Ulu, Musi Rawas, South Sumatera could be used to open new rice fields by planting twice a year. In opening new rice fields, the application of organic matter and creation of terracing on sloping areas were needed.

  7. Mapping subsurface in proximity to newly-developed sinkhole along roadway.

    Science.gov (United States)

    2013-02-01

    MS&T acquired electrical resistivity tomography profiles in immediate proximity to a newly-developed sinkhole in Nixa Missouri : The sinkhole has closed a well-traveled municipal roadway and threatens proximal infrastructure. The intent of this inves...

  8. A newly developed maneuver, field change conversion (FCC), improved evaluation of the left ventricular volume more accurately on quantitative gated SPECT (QGS) analysis

    International Nuclear Information System (INIS)

    Tajima, Osamu; Shibasaki, Masaki; Hoshi, Toshiko; Imai, Kamon

    2002-01-01

    The purpose of this study was to investigate whether a newly developed maneuver that reduces the reconstruction area by a half more accurately evaluates left ventricular (LV) volume on quantitative gated SPECT (QGS) analysis. The subjects were 38 patients who underwent left ventricular angiography (LVG) followed by G-SPECT within 2 weeks. Acquisition was performed with a general purpose collimator and a 64 x 64 matrix. On QGS analysis, the field magnification was 34 cm in original image (Original: ORI), and furthermore it was changed from 34 cm to 17 cm to enlarge the re-constructed image (Field Change Conversion: FCC). End-diastolic volume (EDV) and end-systolic volume (ESV) of the left ventricle were also obtained using LVG. EDV was 71±19 ml, 83±20 ml and 98±23 ml for ORI, FCC and LVG, respectively (p<0.001: ORI versus LVG, p<0.001: ORI versus FCC, p<0.001: FCC versus LVG). ESV was 28±12 ml, 34±13 ml and 41±14 ml for ORI, FCC and LVG, respectively (p<0.001: ORI versus LVG, p<0.001: ORI versus FCC, p<0.001: FCC versus LVG). FCC was better than ORI for calculating LV volume in clinical cases. Furthermore, FCC is a useful method for accurately measuring the LV volume on QGS analysis. (author)

  9. The risk of newly developed visual impairment in treated normal-tension glaucoma: 10-year follow-up.

    Science.gov (United States)

    Choi, Yun Jeong; Kim, Martha; Park, Ki Ho; Kim, Dong Myung; Kim, Seok Hwan

    2014-12-01

    To investigate the risk and risk factors for newly developed visual impairment in treated patients with normal-tension glaucoma (NTG) followed up on for 10 years. Patients with NTG, who did not have visual impairment at the initial diagnosis and had undergone intraocular pressure (IOP)-lowering treatment for more than 7 years, were included on the basis of a retrospective chart review. Visual impairment was defined as either low vision (0.05 [20/400] ≤ visual acuity (VA) visual field (VF) visual impairment, Kaplan-Meier survival analysis and generalized linear mixed effects models were utilized. During the 10.8 years mean follow-up period, 20 eyes of 16 patients were diagnosed as visual impairment (12 eyes as low vision, 8 as blindness) among 623 eyes of 411 patients. The cumulative risk of visual impairment in at least one eye was 2.8% at 10 years and 8.7% at 15 years. The risk factors for visual impairment from treated NTG were worse VF mean deviation (MD) at diagnosis and longer follow-up period. The risk of newly developed visual impairment in the treated patients with NTG was relatively low. Worse VF MD at diagnosis and longer follow-up period were associated with development of visual impairment. © 2014 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  10. High acceptability of a newly developed urological practical skills training program.

    NARCIS (Netherlands)

    Vries, A.H. de; Luijk, S.J. van; Scherpbier, A.J.J.A.; Hendrikx, A.J.M.; Koldewijn, E.L.; Wagner, C.; Schout, B.M.A.

    2015-01-01

    Background: Benefits of simulation training are widely recognized, but its structural implementation into urological curricula remains challenging. This study aims to gain insight into current and ideal urological practical skills training and presents the outline of a newly developed skills

  11. High acceptability of a newly developed urological practical skills training program

    NARCIS (Netherlands)

    de Vries, A.H.; van Luijk, S.J.; Scherpbier, A.J.J.A.; Hendrikx, A.J.M.; Koldewijn, E.L.; Wagner, C.; Schout, B.M.A.

    2015-01-01

    Background: Benefits of simulation training are widely recognized, but its structural implementation into urological curricula remains challenging. This study aims to gain insight into current and ideal urological practical skills training and presents the outline of a newly developed skills

  12. Development of an adjoint sensitivity field-based treatment-planning technique for the use of newly designed directional LDR sources in brachytherapy.

    Science.gov (United States)

    Chaswal, V; Thomadsen, B R; Henderson, D L

    2012-02-21

    The development and application of an automated 3D greedy heuristic (GH) optimization algorithm utilizing the adjoint sensitivity fields for treatment planning to assess the advantage of directional interstitial prostate brachytherapy is presented. Directional and isotropic dose kernels generated using Monte Carlo simulations based on Best Industries model 2301 I-125 source are utilized for treatment planning. The newly developed GH algorithm is employed for optimization of the treatment plans for seven interstitial prostate brachytherapy cases using mixed sources (directional brachytherapy) and using only isotropic sources (conventional brachytherapy). All treatment plans resulted in V100 > 98% and D90 > 45 Gy for the target prostate region. For the urethra region, the D10(Ur), D90(Ur) and V150(Ur) and for the rectum region the V100cc, D2cc, D90(Re) and V90(Re) all are reduced significantly when mixed sources brachytherapy is used employing directional sources. The simulations demonstrated that the use of directional sources in the low dose-rate (LDR) brachytherapy of the prostate clearly benefits in sparing the urethra and the rectum sensitive structures from overdose. The time taken for a conventional treatment plan is less than three seconds, while the time taken for a mixed source treatment plan is less than nine seconds, as tested on an Intel Core2 Duo 2.2 GHz processor with 1GB RAM. The new 3D GH algorithm is successful in generating a feasible LDR brachytherapy treatment planning solution with an extra degree of freedom, i.e. directionality in very little time.

  13. Development of an adjoint sensitivity field-based treatment-planning technique for the use of newly designed directional LDR sources in brachytherapy

    Science.gov (United States)

    Chaswal, V.; Thomadsen, B. R.; Henderson, D. L.

    2012-02-01

    The development and application of an automated 3D greedy heuristic (GH) optimization algorithm utilizing the adjoint sensitivity fields for treatment planning to assess the advantage of directional interstitial prostate brachytherapy is presented. Directional and isotropic dose kernels generated using Monte Carlo simulations based on Best Industries model 2301 I-125 source are utilized for treatment planning. The newly developed GH algorithm is employed for optimization of the treatment plans for seven interstitial prostate brachytherapy cases using mixed sources (directional brachytherapy) and using only isotropic sources (conventional brachytherapy). All treatment plans resulted in V100 > 98% and D90 > 45 Gy for the target prostate region. For the urethra region, the D10Ur, D90Ur and V150Ur and for the rectum region the V100cc, D2cc, D90Re and V90Re all are reduced significantly when mixed sources brachytherapy is used employing directional sources. The simulations demonstrated that the use of directional sources in the low dose-rate (LDR) brachytherapy of the prostate clearly benefits in sparing the urethra and the rectum sensitive structures from overdose. The time taken for a conventional treatment plan is less than three seconds, while the time taken for a mixed source treatment plan is less than nine seconds, as tested on an Intel Core2 Duo 2.2 GHz processor with 1GB RAM. The new 3D GH algorithm is successful in generating a feasible LDR brachytherapy treatment planning solution with an extra degree of freedom, i.e. directionality in very little time.

  14. Interocular asymmetry of the visual field defects in newly diagnosed normal-tension glaucoma, primary open-angle glaucoma, and chronic angle-closure glaucoma.

    Science.gov (United States)

    Huang, Ping; Shi, Yan; Wang, Xin; Liu, Mugen; Zhang, Chun

    2014-09-01

    To compare the interocular asymmetry of visual field loss in newly diagnosed normal-tension glaucoma (NTG), primary open-angle glaucoma (POAG), and chronic angle-closure glaucoma (CACG) patients. Visual field results of 117 newly diagnosed, treatment-naive glaucoma patients (42 NTG, 38 POAG, and 37 CACG) were studied retrospectively. The following 3 visual field defect parameters were used to evaluate the interocular asymmetry: (1) global indices; (2) local mean deviations (MDs) of 6 predefined visual field areas; and (3) stage designated by glaucoma staging system 2. The differences of the above parameters between the trial eye (the eye with greater MDs) and the fellow eye in each subject were defined as interocular asymmetry scores. Interocular asymmetry of visual field loss was presented in all the 3 groups (all P0.05). Interocular asymmetry scores of glaucoma staging system 2 had no significant difference among the 3 groups (P=0.068). All CACG, POAG, and NTG groups presented with interocular asymmetric visual field loss at the time of diagnosis. CACG had greater interocular asymmetry compared with NTG and POAG. No significant interocular asymmetry difference was observed between NTG and POAG.

  15. Establishment probability in newly founded populations

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    Gusset Markus

    2012-06-01

    Full Text Available Abstract Background Establishment success in newly founded populations relies on reaching the established phase, which is defined by characteristic fluctuations of the population’s state variables. Stochastic population models can be used to quantify the establishment probability of newly founded populations; however, so far no simple but robust method for doing so existed. To determine a critical initial number of individuals that need to be released to reach the established phase, we used a novel application of the “Wissel plot”, where –ln(1 – P0(t is plotted against time t. This plot is based on the equation P0t=1–c1e–ω1t, which relates the probability of extinction by time t, P0(t, to two constants: c1 describes the probability of a newly founded population to reach the established phase, whereas ω1 describes the population’s probability of extinction per short time interval once established. Results For illustration, we applied the method to a previously developed stochastic population model of the endangered African wild dog (Lycaon pictus. A newly founded population reaches the established phase if the intercept of the (extrapolated linear parts of the “Wissel plot” with the y-axis, which is –ln(c1, is negative. For wild dogs in our model, this is the case if a critical initial number of four packs, consisting of eight individuals each, are released. Conclusions The method we present to quantify the establishment probability of newly founded populations is generic and inferences thus are transferable to other systems across the field of conservation biology. In contrast to other methods, our approach disaggregates the components of a population’s viability by distinguishing establishment from persistence.

  16. Physicochemical properties of newly developed bioactive glass cement and its effects on various cells.

    Science.gov (United States)

    Washio, Ayako; Nakagawa, Aika; Nishihara, Tatsuji; Maeda, Hidefumi; Kitamura, Chiaki

    2015-02-01

    Biomaterials used in dental treatments are expected to have favorable properties such as biocompatibility and an ability to induce tissue formation in dental pulp and periapical tissue, as well as sealing to block external stimuli. Bioactive glasses have been applied in bone engineering, but rarely applied in the field of dentistry. In the present study, bioactive glass cement for dental treatment was developed, and then its physicochemical properties and effects on cell responses were analyzed. To clarify the physicochemical attributes of the cement, field emission scanning electron microscopy, X-ray diffraction, and pH measurement were carried out. Cell attachment, morphology, and viability to the cement were also examined to clarify the effects of the cement on odontoblast-like cells (KN-3 cells), osteoblastic cells (MC3T3-E1 cells), human periodontal ligament stem/progenitor cells and neuro-differentiative cells (PC-12 cells). Hydroxyapatite-like precipitation was formed on the surface of the hardened cement and the pH level changed from pH10 to pH9, then stabilized in simulate body fluid. The cement had no cytotxic effects on these cells, and particulary induced process elongation of PC-12 cells. Our results suggest that the newly developed bioactive glass cement have capability of the application in dental procedures as bioactive cement. © 2014 Wiley Periodicals, Inc.

  17. Study of surface energy budget and test of a newly developed fast photoacoustic spectroscopy based hygrometer in field campaign Szeged (Hungary)

    Science.gov (United States)

    Tatrai, David; Nikov, Daniella; Zsolt Jász, Ervin; Bozóki, Zoltán; Szabó, Gábor; Weidinger, Tamás; András Gyöngyösi, Zénó; Kiss, Melinda; Józsa, János; Simó Diego, Gemma; Cuxart Rodamilans, Joan; Wrenger, Burkhart; Bottyán, Zsolt

    2014-05-01

    A micrometeorological field measurement campaign dedicated to study the surface energy budget and the structure of the boundary layer focusing on the transient layer forming periods during night-time was organized in the period of 10th of November to 3rd of December 2013 in the nearby of Szeged, Hungary. A temporary micrometeorological measurement station was set up at the coordinates N:46.239943; E:20.089758, approximately 1700 m far from a national meteorology station (N:46.255711; E:20.09052). In the experimental micrometeorological site different types of instruments were installed to measure numerous parameters: standard meteorological measurements (p, T, wet, wind speed and direction at three different levels, relative humidity at two levels and absolute humidity at one level) radiation budget components surface temperature and leaf wetness soil temperature, moisture and heat flux into the deeper soil layer eddy-covariance measurements (t, H, LE CO2) at 3 m level using Campbell open-path IRGA (EC150) system. At the national meteorology station (http://adatok.geo.u-szeged.hu/?lang=eng) besides their standard measurement equipment and measurement routine a SODAR was installed and continuously operated. These ground based measurements were combined with and supported by UAV, quadcopter and tethered balloon based vertical profile measurements of p, T, rh. For this measurement campaign as a modification of a previously developed airborne ready dual channel hygrometer, a fast photoacoustic spectroscopy based hygrometer was developed for absolute humidity measurements. The estimated response time of the system is faster than 15 Hz, which was achieved by the replacement of the data acquisition system and by recording the raw photoacoustic signal sampled at rate of 48 kHz for post-processing. During the campaign this new system was compared to a TDL system commercially available at Li-COR Inc. Besides the testing of the newly developed fast photoacoustic hygrometer

  18. Development of a measuring system for poloidal field profile in JIPP T-IIU plasmas

    International Nuclear Information System (INIS)

    Kuramoto, Hideharu; Hiraki, Naoji; Moriyama, Shin-ichi; Toi, Kazuo; Sato, Kuninori.

    1995-01-01

    A Zeeman polarimeter has been developed to measure the poloidal magnetic field profile in the plasma edge of the JIPP T-IIU tokamak. The poloidal field strength is determined from the analysis of circular polarization of a HeII 4686A spectral lines emitted from a plasma. The polarization modulation rate, which is proportional to the magnetic field strength along a line of sight, is estimated as a ratio of the difference between the left-hand circular polarized line intensity and right-hand one to the sum of them. A newly developed fast scanning Fabry-Perot interferometer allows us to improve a time resolution up to 1.5 ms. The poloidal magnetic field profile in He-doped deuterium plasmas of JIPP T-IIU has been successfully obtained with this polarimeter system. (author)

  19. Improving a newly developed patient-reported outcome for thyroid patients, using cognitive interviewing

    DEFF Research Database (Denmark)

    Watt, Torquil; Rasmussen, Ase Krogh; Groenvold, Mogens

    2008-01-01

    Objective To improve a newly developed patient-reported outcome measure for thyroid patients using cognitive interviewing. Methods Thirty-one interviews using immediate retrospective and expansive probing were conducted among patients with non-toxic goiter (n = 4), nodular toxic goiter (n = 5) Gr...

  20. Newly Developed Ceramic Membranes for Dehydration and Separation of Organic Mixtures by Pervaporation

    NARCIS (Netherlands)

    Gemert, van R.W.; Cuperus, F.P.

    1995-01-01

    Polymeric pervaporation membranes sometimes show great variety in performance when they are alternately used for different solvent mixtures. In addition, membrane stability in time is a problem in case of some solvents. Therefore, newly developed ceramic silica membranes with a 'dense' top layer

  1. The Development Needs of Newly Appointed Senior School Leaders in the Western Cape South Africa: A Case Study

    Directory of Open Access Journals (Sweden)

    Nelius Jansen van Vuuren

    2017-12-01

    Full Text Available The essential role that senior school leaders play in school leadership teams to ensure effective strategic leadership in schools has been the subject of intense discussion for many years. Crucial to this debate is the establishment of professional learning and leadership approaches for newly appointed senior school leaders. Recommendations for policy and practice highlight the importance of appropriate, multifaceted, developmental support initiatives for newly appointed school leaders. In many countries, including South Africa, a teaching qualification and, in most cases, extensive teaching experience is the only requirement for being appointed as a senior school leader in a school. This tends to suggest that no further professional development is required for newly appointed school leaders, the problem addressed in this paper. This paper reports on the main findings of the perceived development needs of newly appointed senior school leaders in the Western Cape, South Africa, and suggests that school leaders occupy a unique and specialist role in education, which requires relevant and specific preparation to support effective leadership. The respondents of this study report a lack of contextualised training and support before and after their appointment in their new roles creating unique development needs. This paper, therefore, employs a mixed-method approach to gather data to understand the perceived needs of twenty newly appointed senior school leaders in the Western Cape, South Africa.

  2. Use of a newly developed active thermal neutron detector for in-phantom measurements in a medical LINAC

    Energy Technology Data Exchange (ETDEWEB)

    Bodogni, R.; Sanchez-Doblado, F.; Pola, A.; Gentile, A.; Esposito, A.; Gomez-ros, J. M.; Pressello, M. C.; Lagares, J. I.; Terron, J. A.; Gomez, F.

    2013-07-01

    In this work a newly developed active thermal neutron detector, based on a solid state analog device, was used to determine the thermal neutron fluence in selected positions of a simplified human phantom undergoing radiotherapy with a 15 MV LINAC. The results are compared with TLD, the predictions from a Monte Carlo simulation and with measurements indirectly performed with a digital device, located far from the phantom, inside the treatment room. In this work only TLD comparison is presented. Since active neutron instruments are usually affected by systematic deviations when used in a pulsed field with large photon background, the new detector offered in this work may represent an innovative and useful tool for neutron evaluations in accelerator-based radiotherapy. (Author)

  3. Validating self-reported mobile phone use in adults using a newly developed smartphone application

    NARCIS (Netherlands)

    Goedhart, Geertje; Kromhout, Hans; Wiart, Joe; Vermeulen, Roel

    2015-01-01

    OBJECTIVE: Interpretation of epidemiological studies on health effects from mobile phone use is hindered by uncertainties in the exposure assessment. We used a newly developed smartphone application (app) to validate self-reported mobile phone use and behaviour among adults. METHODS: 107

  4. Micro-computed tomography newly developed for in vivo small animal imaging

    International Nuclear Information System (INIS)

    Arai, Yoshinori; Ninomiya, Tadashi; Kato, Takafumi; Masuda, Yuji

    2005-01-01

    The aim of this paper is to report a newly developed micro-computed tomography system for in vivo use. The system was composed of a micro-focus X-ray tube and an image intensifier (I.I.), both of which rotated around the object stage. A guinea pig and a rat were examined. The anesthetized animal was set on the secure object stage. Images of the head of the guinea pig and the tibia knee joint of the rat were taken. In addition, an image of the rat's tail was taken. The reconstruction and the image viewing were carried out using I-View software. The voxel matrix was 512 x 512 x 384. The voxel sizes ranged from 10 x 10 x 10 μm to 100 x 100 x 100 μm. The exposure time was 17 s, and the reconstruction time was 150 s. The head of the guinea pig and the tibia/knee joint of the rat were observed clearly under 100-μm and 30μm voxels, respectively. The trabecular bone of the tail was also observed clearly under a 10 μm voxel. The newly developed micro-computed tomography system makes it possible to obtain images of anesthetized animals set on a secure object stage. Clear bone images of the small animals could be obtained within a short time. (author)

  5. Assessing College Students' Perceptions of a Case Teacher's Pedagogical Content Knowledge Using a Newly Developed Instrument

    Science.gov (United States)

    Jang, Syh-Jong

    2011-01-01

    Ongoing professional development for college teachers has been much emphasized. However, previous research on learning environments has seldom addressed college students' perceptions of teachers' PCK. This study aimed to evaluate college students' perceptions of a physics teacher's PCK development using a newly developed instrument and workshop…

  6. Applicability of newly developed 610MPa class heavy thickness high strength steel to boiler pressure vessel

    Energy Technology Data Exchange (ETDEWEB)

    Katayama, Norihiko; Kaihara, Shoichiro; Ishii, Jun [Ishikawajima-Harima Heavy Industries Corp., Yokohama (Japan); Kajigaya, Ichiro [Ishikawajima-Harima Heavy Industries Corp., Tokyo (Japan); Totsuka, Takehiro; Miyazaki, Takashi [Ishikawajima-Harima Heavy Industries Corp., Aioi (Japan)

    1995-11-01

    Construction of a 350 MW Class PFBC (Pressurized Fluidized Bed Combustion) boiler plant is under planning in Japan. Design temperature and pressure of the vessel are maximum 350 C and 1.69 MPa, respectively. As the plate thickness of the vessel exceeds over 100 mm, high strength steel plate of good weldability and less susceptible to reheat cracking was required and developed. The steel was aimed to satisfy the tensile strength over 610 MPa at 350 C after postweld heat treatment (PWHT), with good notch toughness. The authors investigated the welding performances of the newly developed steel by using 150 mm-thick plate welded by pulsed-MAG and SAW methods. It was confirmed that the newly developed steel and its welds possess sufficient strength and toughness after PWHT, and applicable to the actual pressure vessel.

  7. Fundamental Characteristics of the Newly Developed ATA™ Membrane Dialyzer.

    Science.gov (United States)

    Sunohara, Takashi; Masuda, Toshiaki

    2017-01-01

    Dialysis membranes are often made from synthetic polymers, such as polysulfone. However, membranes made from cellulose triacetate have superior biocompatibility and have been used since the 1980s. On-line hemodiafiltration treatment accompanied by massive fluid replacement is increasingly being used in Europe and Japan, but cellulose triacetate is not suitable for this treatment. Our newly developed asymmetric triacetate membrane, the ATA™ membrane, substantially improved the filtration properties and blood compatibility because of the asymmetric structure and smooth surface of this cellulose acetate membrane. Key Message: The ATA membrane maintains its high permeability even after massive filtration and shows less temporal variation in its permeation performance, lower protein adsorption, and superior biocompatibility compared with conventional membranes. © 2017 S. Karger AG, Basel.

  8. Speciation analysis of I-127,129 in the crop field soil contaminated by the Fukushima Dai-ichi nuclear power plant accident with newly developed chemical separation techniques

    Science.gov (United States)

    Honda, Maki; Matsuzaki, Hiroyuki; Saito, Takumi; Nagai, Hisao

    2014-05-01

    In previous study, we investigated the depth profile of the accident derived I-129 and downward migration speed in soils of near-field of Fukushima Dai-ichi Nuclear Power Plant, including crop fields and man-made fields. I-129 in soil was measured by AMS and stable iodine (I-127) was measured by ICP-MS at MALT (Micro Analysis Laboratory, Tandem accelerator), The University of Tokyo. It was found that I-129 was concentrated near surface but distributed deeper compared with Cs-137. It was also found that I-129 seems to move downward more quickly than Cs-137. To investigate the adsorption mechanism and the elemental process of migration of the accident derived I-129 in soil, it is important to know what kind of component the I-129 combines with. Recent studies on the X-ray absorption fine structure (XAFS), especially near edge structure (XANES), reported that the stable iodine (I-127) in soil existed as an organic component. However, it had not yet been proved that it was also the case with the accident derived I-129 because it had been incorporated in the soil system only recently and the abundance of I-129 in soil was more than 8 orders of magnitude smaller than sub-ppm level stable iodine (I-127). In this study a progressive sequential extraction method including the dialysis and the dynamic headspace method was newly developed to obtain only the iodine sticking to the soil organic component. The stable iodine can be quantified by direct analysis of the fraction and I-129 can be quantified by AMS method of the fraction added with carrier. The fraction of the organic component for I-127 and I-129 can be evaluated respectively by comparing with the other fraction and/or with the total concentration obtained by the bulk analysis (e.g. by the pyrohydrolysis).

  9. PHL10/460: Cancerfacts.com - Vertical Portal with Newly Developed Health Profiler

    OpenAIRE

    Lenz, C; Brucksch, M

    1999-01-01

    Introduction Unlike general health portals such as WebMD and Drkoop.com that cover everything from the flu to heart disease, Silicon Valley-based cancerfacts.com is a so-called vertical portal. It covers only one small vertical niche of health care: cancer, and in particular, prostate cancer. As a value-added proprietary technology, the company offers its newly developed profile engine to health information retrievers. Methods Users are enabled to insert their specific medical information - r...

  10. Research in the field of development of a new generation of metal-processing machines

    Directory of Open Access Journals (Sweden)

    L.Tanovič

    2017-12-01

    Full Text Available The paper presents a review of research in the field of development of a new generation of metal-working machines for manufacturing high-precision products with dimensions of several micrometers from various materials. Presented are several new, newly created micro-machines that have the ability to manufacture products of a wide range. Studies in the field of metalworking machines and robots of a new generation with parallel kinematics, creation of machining systems for multi-axis machining, improvement and application of controllable systems, testing of processing systems in production conditions, which are conducted at the Machine-Building Faculty of the Belgrade University (Serbia are considered.

  11. Newly developed semi-empirical formulas for (p, α) at 17.9 MeV and ...

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics; Volume 74; Issue 6. Newly developed semi-empirical formulas for (, ) at 17.9 MeV and (, ) at 22.3 MeV reaction cross-sections. Eyyup Tel Abdullah Aydin E Gamze Aydin Abdullah Kaplan Ömer Yavaş İskender A Reyhancan. Research Articles Volume 74 Issue 6 June ...

  12. The newly developed Toyota plug-in hybrid system

    Energy Technology Data Exchange (ETDEWEB)

    Takaoka, Toshifumi; Ichinose, Hiroki [Toyota Motor Corporation (Japan)

    2010-07-01

    Toyota has been introducing several hybrid vehicles (HV) as a countermeasure to the automobile's concerns, like CO2 reduction, energy security, and emission reduction in urban areas. A next step towards an even more effective solution for these concerns is a plug-in hybrid vehicle (PHV). This vehicle combines the advantages of electric vehicles (EV), which use clean electric energy, and HV, with it's high environmental potential and user- friendliness comparable to conventional vehicles, such as a long cruising range. This paper describes a newly developed plug-in hybrid system and its vehicle performance. This system uses a Li-ion battery with high energy density and has an affordable EV range without sacrificing cabin space. The vehicle achieves a CO2 emission of 59g/km and meets the most stringent emission regulations in the world. The new PHV is a forerunner of the large-scale mass production PHV two years later. PHVs have the potential to become popular as a realistic solution towards sustainable mobility by renewable electricity usage in the future. (orig.)

  13. Verification of gamma knife based fractionated radiosurgery with newly developed head-thorax phantom

    International Nuclear Information System (INIS)

    Bisht, Raj Kishor; Kale, Shashank Sharad; Natanasabapathi, Gopishankar; Singh, Manmohan Jit; Agarwal, Deepak; Garg, Ajay; Rath, Goura Kishore; Julka, Pramod Kumar; Kumar, Pratik; Thulkar, Sanjay; Sharma, Bhawani Shankar

    2016-01-01

    Objective: Purpose of the study is to verify the Gamma Knife Extend™ system (ES) based fractionated stereotactic radiosurgery with newly developed head-thorax phantom. Methods: Phantoms are extensively used to measure radiation dose and verify treatment plan in radiotherapy. A human upper body shaped phantom with thorax was designed to simulate fractionated stereotactic radiosurgery using Extend™ system of Gamma Knife. The central component of the phantom aids in performing radiological precision test, dosimetric evaluation and treatment verification. A hollow right circular cylindrical space of diameter 7.0 cm was created at the centre of this component to place various dosimetric devices using suitable adaptors. The phantom is made of poly methyl methacrylate (PMMA), a transparent thermoplastic material. Two sets of disk assemblies were designed to place dosimetric films in (1) horizontal (xy) and (2) vertical (xz) planes. Specific cylindrical adaptors were designed to place thimble ionization chamber inside phantom for point dose recording along xz axis. EBT3 Gafchromic films were used to analyze and map radiation field. The focal precision test was performed using 4 mm collimator shot in phantom to check radiological accuracy of treatment. The phantom head position within the Extend™ frame was estimated using encoded aperture measurement of repositioning check tool (RCT). For treatment verification, the phantom with inserts for film and ion chamber was scanned in reference treatment position using X-ray computed tomography (CT) machine and acquired stereotactic images were transferred into Leksell Gammaplan (LGP). A patient treatment plan with hypo-fractionated regimen was delivered and identical fractions were compared using EBT3 films and in-house MATLAB codes. Results: RCT measurement showed an overall positional accuracy of 0.265 mm (range 0.223 mm–0.343 mm). Gamma index analysis across fractions exhibited close agreement between LGP and film

  14. How Schools Can Promote Healthy Development for Newly Arrived Immigrant and Refugee Adolescents: Research Priorities

    Science.gov (United States)

    McNeely, Clea A.; Morland, Lyn; Doty, S. Benjamin; Meschke, Laurie L.; Awad, Summer; Husain, Altaf; Nashwan, Ayat

    2017-01-01

    Background: The US education system must find creative and effective ways to foster the healthy development of the approximately 2 million newly arrived immigrant and refugee adolescents, many of whom contend with language barriers, limited prior education, trauma, and discrimination. We identify research priorities for promoting the school…

  15. A computer literacy scale for newly enrolled nursing college students: development and validation.

    Science.gov (United States)

    Lin, Tung-Cheng

    2011-12-01

    Increasing application and use of information systems and mobile technologies in the healthcare industry require increasing nurse competency in computer use. Computer literacy is defined as basic computer skills, whereas computer competency is defined as the computer skills necessary to accomplish job tasks. Inadequate attention has been paid to computer literacy and computer competency scale validity. This study developed a computer literacy scale with good reliability and validity and investigated the current computer literacy of newly enrolled students to develop computer courses appropriate to students' skill levels and needs. This study referenced Hinkin's process to develop a computer literacy scale. Participants were newly enrolled first-year undergraduate students, with nursing or nursing-related backgrounds, currently attending a course entitled Information Literacy and Internet Applications. Researchers examined reliability and validity using confirmatory factor analysis. The final version of the developed computer literacy scale included six constructs (software, hardware, multimedia, networks, information ethics, and information security) and 22 measurement items. Confirmatory factor analysis showed that the scale possessed good content validity, reliability, convergent validity, and discriminant validity. This study also found that participants earned the highest scores for the network domain and the lowest score for the hardware domain. With increasing use of information technology applications, courses related to hardware topic should be increased to improve nurse problem-solving abilities. This study recommends that emphases on word processing and network-related topics may be reduced in favor of an increased emphasis on database, statistical software, hospital information systems, and information ethics.

  16. Newly developed chitosan-silver hybrid nanoparticles: biosafety and apoptosis induction in HepG2 cells

    International Nuclear Information System (INIS)

    El-Sherbiny, Ibrahim M.; Salih, Ehab; Yassin, Abdelrahman M.; Hafez, Elsayed E.

    2016-01-01

    The present study reports the biosafety assessment, the exact molecular effects, and apoptosis induction of newly developed chitosan-silver hybrid nanoparticles (Cs–Ag NPs) in HepG2 cells. The investigated hybrid NPs were green synthesized using Cs/grape leaves aqueous extract (Cs/GLE) or Cs/GLE NPs as reducing and stabilizing agents. The successful formation of Cs/GLE NPs and Cs–Ag hybrid NPs has been confirmed by UV–Vis spectrophotometry, FTIR spectroscopy, XRD, and HRTEM. From the TEM analysis, the prepared Cs/GLE NPs are uniform and spherical with an average size of 150 nm, and the AgNPs (5–10 nm) were formed mainly on their surface. The UV–Vis spectra of Cs–Ag NPs showed a surface plasmon resonance (SPR) peak at about 450 nm confirming their formation. The synthesized Cs–Ag NPs were found to be crystalline as shown by XRD patterns with fcc phase oriented along the (111), (200), (220), and (311) planes. The cytotoxicity patterns, the antiproliferative activities, and the possible mechanisms of anticancer activity at molecular level of the newly developed Cs–Ag hybrid NPs were investigated. Cytotoxicity patterns of all the preparations demonstrated that the nontoxic treatment concentrations are ranged from 0.39 to 50 %, and many of the newly prepared Cs–Ag hybrid NPs showed high anticancer activities against HpG2 cells, and induced cellular apoptosis by downregulating BCL2 gene and upregulating P53.Graphical Abstract

  17. Newly developed chitosan-silver hybrid nanoparticles: biosafety and apoptosis induction in HepG2 cells

    Energy Technology Data Exchange (ETDEWEB)

    El-Sherbiny, Ibrahim M., E-mail: ielsherbiny@Zewailcity.edu.eg; Salih, Ehab [Zewail City of Science and Technology, Center for Materials Science (Egypt); Yassin, Abdelrahman M. [Genetic Engineering and Biotechnology Research Institute, City of Scientific Research and Technology Applications, Biopharmaceutical Product Research Department (Egypt); Hafez, Elsayed E. [City of Scientific Research and Technology Applications, Plant Protection and Biomolecular Diagnosis Department (Egypt)

    2016-07-15

    The present study reports the biosafety assessment, the exact molecular effects, and apoptosis induction of newly developed chitosan-silver hybrid nanoparticles (Cs–Ag NPs) in HepG2 cells. The investigated hybrid NPs were green synthesized using Cs/grape leaves aqueous extract (Cs/GLE) or Cs/GLE NPs as reducing and stabilizing agents. The successful formation of Cs/GLE NPs and Cs–Ag hybrid NPs has been confirmed by UV–Vis spectrophotometry, FTIR spectroscopy, XRD, and HRTEM. From the TEM analysis, the prepared Cs/GLE NPs are uniform and spherical with an average size of 150 nm, and the AgNPs (5–10 nm) were formed mainly on their surface. The UV–Vis spectra of Cs–Ag NPs showed a surface plasmon resonance (SPR) peak at about 450 nm confirming their formation. The synthesized Cs–Ag NPs were found to be crystalline as shown by XRD patterns with fcc phase oriented along the (111), (200), (220), and (311) planes. The cytotoxicity patterns, the antiproliferative activities, and the possible mechanisms of anticancer activity at molecular level of the newly developed Cs–Ag hybrid NPs were investigated. Cytotoxicity patterns of all the preparations demonstrated that the nontoxic treatment concentrations are ranged from 0.39 to 50 %, and many of the newly prepared Cs–Ag hybrid NPs showed high anticancer activities against HpG2 cells, and induced cellular apoptosis by downregulating BCL2 gene and upregulating P53.Graphical Abstract.

  18. A newly development RIA for thyroid hormone autoantibodies (THAAb)

    International Nuclear Information System (INIS)

    Li Fengying; Gu Liqiong; Chen Xiayin; Jin Yan; Chen Shuxian; Zhang Qun; Qiu Hongxia; Yang Jingren; Zhao Yongju; Chen Mingdao

    2004-01-01

    Objective: To report a newly developed RIA for THAAb from this laboratory. Methods: The tested serum samples were cultured with labelled thyroid hormone analogous ( 125 I T 3 , 125 I T 4 ) for 16 hours. Antigen-antibody complex was precipitated with anti-human IgG (immune precipitation method) and radio-activity determined. Results: The mean positive rate of THAAb in healthy euthyroid controls (n=186) was only 1.07%. The mean positive rate in patients with thyroid disorders was 14.4% (mean rate 13.5% in hyperthyroid subjects, n=118 and mean rate 15.2% in hypothyroid subjects, n=72). The serum THAAb titer could be markedly lowered after adding non-labelled thyroid hormones (P 3 and FT 4 would be significantly lowered (P 3 , FT 4 levels. In patients with positive THAAb (about 14.4% in patients with all thyroid disorders), the FT 3 , FT 4 levels were best determined after PEG precipitation. (authors)

  19. Muscle Attenuation Is Associated With Newly Developed Hypertension in Men of African Ancestry.

    Science.gov (United States)

    Zhao, Qian; Zmuda, Joseph M; Kuipers, Allison L; Bunker, Clareann H; Patrick, Alan L; Youk, Ada O; Miljkovic, Iva

    2017-05-01

    Increased ectopic adipose tissue infiltration in skeletal muscle is associated with insulin resistance and diabetes mellitus. We evaluated whether change in skeletal muscle adiposity predicts subsequent development of hypertension in men of African ancestry, a population sample understudied in previous studies. In the Tobago Health Study, a prospective longitudinal study among men of African ancestry (age range 40-91 years), calf intermuscular adipose tissue, and skeletal muscle attenuation were measured with computed tomography. Hypertension was defined as a systolic blood pressure ≥140 mm Hg, or a diastolic blood pressure ≥90 mm Hg, or receiving antihypertensive medications. Logistic regression was performed with adjustment for age, insulin resistance, baseline and 6-year change in body mass index, baseline and 6-year change in waist circumference, and other potential confounding factors. Among 746 normotensive men at baseline, 321 (43%) developed hypertension during the mean 6.2 years of follow-up. Decreased skeletal muscle attenuation was associated with newly developed hypertension after adjustment for baseline and 6-year change of body mass index (odds ratio [95% confidence interval] per SD, 1.3 [1.0-1.6]) or baseline and 6-year change of waist circumference (odds ratio [95% confidence interval] per SD, 1.3 [1.0-1.6]). No association was observed between increased intermuscular adipose tissue and hypertension. Our novel findings show that decreased muscle attenuation is associated with newly developed hypertension among men of African ancestry, independent of general and central adiposity and insulin resistance. Further studies are needed to adjust for inflammation, visceral and other ectopic adipose tissue depots, and to confirm our findings in other population samples. © 2017 American Heart Association, Inc.

  20. Can the exposure of Apis mellifera (Hymenoptera, Apiadae) larvae to a field concentration of thiamethoxam affect newly emerged bees?

    Science.gov (United States)

    Friol, Priscila Sepúlveda; Catae, Aline Fernanda; Tavares, Daiana Antonia; Malaspina, Osmar; Roat, Thaisa Cristina

    2017-10-01

    The use of insecticides on crops can affect non-target insects, such as bees. In addition to the adult bees, larvae can be exposed to the insecticide through contaminated floral resources. Therefore, this study aimed to investigate the possible effects of the exposure of A. mellifera larvae to a field concentration of thiamethoxam (0.001 ng/μL thiamethoxam) on larval and pupal survival and on the percentage of adult emergence. Additionally, its cytotoxic effects on the digestive cells of midgut, Malpighian tubules cells and Kenyon cells of the brain of newly emerged A. mellifera bees were analyzed. The results showed that larval exposure to this concentration of thiamethoxam did not influence larval and pupal survival or the percentage of adult bee emergence. However, this exposure caused ultra-structural alterations in the target and non-target organs of newly emerged bees. The digestive cell of bees that were exposed to the insecticide exhibited a basal labyrinth without long and thin channels and compromised mitochondria. In Malpighian tubules cells, disorganized basal labyrinth, dilated mitochondria with a deformed shape and a loss of cristae, and disorganized microvilli were observed. The results showed that the exposed bees presented Kenyon cells with alterations in the nucleus and mitochondria. These alterations indicate possible tissue degeneration, demonstrating the cytotoxicity of thiamethoxam in the target and non-target organs of newly emerged bees. Such results suggest cellular organelle impairment that can compromise cellular function of the midgut cells, Malpighian tubules cells and Kenyon cells, and, consequently, can compromise the longevity of the bees of the whole colony. Copyright © 2017 Elsevier Ltd. All rights reserved.

  1. New light field camera based on physical based rendering tracing

    Science.gov (United States)

    Chung, Ming-Han; Chang, Shan-Ching; Lee, Chih-Kung

    2014-03-01

    Even though light field technology was first invented more than 50 years ago, it did not gain popularity due to the limitation imposed by the computation technology. With the rapid advancement of computer technology over the last decade, the limitation has been uplifted and the light field technology quickly returns to the spotlight of the research stage. In this paper, PBRT (Physical Based Rendering Tracing) was introduced to overcome the limitation of using traditional optical simulation approach to study the light field camera technology. More specifically, traditional optical simulation approach can only present light energy distribution but typically lack the capability to present the pictures in realistic scenes. By using PBRT, which was developed to create virtual scenes, 4D light field information was obtained to conduct initial data analysis and calculation. This PBRT approach was also used to explore the light field data calculation potential in creating realistic photos. Furthermore, we integrated the optical experimental measurement results with PBRT in order to place the real measurement results into the virtually created scenes. In other words, our approach provided us with a way to establish a link of virtual scene with the real measurement results. Several images developed based on the above-mentioned approaches were analyzed and discussed to verify the pros and cons of the newly developed PBRT based light field camera technology. It will be shown that this newly developed light field camera approach can circumvent the loss of spatial resolution associated with adopting a micro-lens array in front of the image sensors. Detailed operational constraint, performance metrics, computation resources needed, etc. associated with this newly developed light field camera technique were presented in detail.

  2. Predictive score for the development or progression of Graves' orbitopathy in patients with newly diagnosed Graves' hyperthyroidism

    DEFF Research Database (Denmark)

    Wiersinga, Wilmar; Žarković, Miloš; Bartalena, Luigi

    2018-01-01

    OBJECTIVE: To construct a predictive score for the development or progression of Graves' orbitopathy (GO) in Graves' hyperthyroidism (GH). DESIGN: Prospective observational study in patients with newly diagnosed GH, treated with antithyroid drugs (ATD) for 18 months at ten participating centers f...

  3. Pressure drop performance evaluation for test assemblies with the newly developed top and bottom nozzles

    International Nuclear Information System (INIS)

    Lee, S. K.; Park, N. K.; Su, J. M.; Kim, H. K.; Lee, J. N.; Kim, K. T.

    2003-01-01

    To perform the hydraulic test for the newly developed top and bottom nozzles, two kinds of test assemblies were manufactured i. e. one is the test assembly which has the newly developed top and bottom nozzles and the other is Guardian test assembly which is commercially in mass production now. The test results show that the test assembly with one top nozzle and two bottom nozzles has a greater pressure loss coefficient than Guardian test assembly by 60.9% and 90.4% at the bottom nozzle location. This cause is due to the debris filtering plate for bottom nozzle to improve a filtering efficiency aginst foreign material. In the region of mid grid and top nozzle, there is no difference in pressure loss coefficient between the test assemblies since the componet features in these regions are very similar or same each other. The loss coefficients are 14.2% and 21.9% for model A and B respectively in the scale of test assembly, and the value would be within the 10% in the scale of real fuel assembly. As a result of hydraulic performance evaluation, model A is superior to model B

  4. How Schools Can Promote Healthy Development for Newly Arrived Immigrant and Refugee Adolescents: Research Priorities.

    Science.gov (United States)

    McNeely, Clea A; Morland, Lyn; Doty, S Benjamin; Meschke, Laurie L; Awad, Summer; Husain, Altaf; Nashwan, Ayat

    2017-02-01

    The US education system must find creative and effective ways to foster the healthy development of the approximately 2 million newly arrived immigrant and refugee adolescents, many of whom contend with language barriers, limited prior education, trauma, and discrimination. We identify research priorities for promoting the school success of these youth. The study used the 4-phase priority-setting method of the Child Health and Nutrition Research Initiative. In the final stage, 132 researchers, service providers, educators, and policymakers based in the United States were asked to rate the importance of 36 research options. The highest priority research options (range 1 to 5) were: evaluating newcomer programs (mean = 4.44, SD = 0.55), identifying how family and community stressors affect newly arrived immigrant and refugee adolescents' functioning in school (mean = 4.40, SD = 0.56), identifying teachers' major stressors in working with this population (mean = 4.36, SD = 0.72), and identifying how to engage immigrant and refugee families in their children's education (mean = 4.35, SD = 0.62). These research priorities emphasize the generation of practical knowledge that could translate to immediate, tangible benefits for schools. Funders, schools, and researchers can use these research priorities to guide research for the highest benefit of schools and the newly arrived immigrant and refugee adolescents they serve. © 2017, American School Health Association.

  5. A multi-method approach to curriculum development for in-service training in China's newly established health emergency response offices.

    Directory of Open Access Journals (Sweden)

    Yadong Wang

    Full Text Available To describe an innovative approach for developing and implementing an in-service curriculum in China for staff of the newly established health emergency response offices (HEROs, and that is generalisable to other settings.The multi-method training needs assessment included reviews of the competency domains needed to implement the International Health Regulations (2005 as well as China's policies and emergency regulations. The review, iterative interviews and workshops with experts in government, academia, the military, and with HERO staff were reviewed critically by an expert technical advisory panel.Over 1600 participants contributed to curriculum development. Of the 18 competency domains identified as essential for HERO staff, nine were developed into priority in-service training modules to be conducted over 2.5 weeks. Experts from academia and experienced practitioners prepared and delivered each module through lectures followed by interactive problem-solving exercises and desktop simulations to help trainees apply, experiment with, and consolidate newly acquired knowledge and skills.This study adds to the emerging literature on China's enduring efforts to strengthen its emergency response capabilities since the outbreak of SARS in 2003. The multi-method approach to curriculum development in partnership with senior policy-makers, researchers, and experienced practitioners can be applied in other settings to ensure training is responsive and customized to local needs, resources and priorities. Ongoing curriculum development should reflect international standards and be coupled with the development of appropriate performance support systems at the workplace for motivating staff to apply their newly acquired knowledge and skills effectively and creatively.

  6. A multi-method approach to curriculum development for in-service training in China's newly established health emergency response offices.

    Science.gov (United States)

    Wang, Yadong; Li, Xiangrui; Yuan, Yiwen; Patel, Mahomed S

    2014-01-01

    To describe an innovative approach for developing and implementing an in-service curriculum in China for staff of the newly established health emergency response offices (HEROs), and that is generalisable to other settings. The multi-method training needs assessment included reviews of the competency domains needed to implement the International Health Regulations (2005) as well as China's policies and emergency regulations. The review, iterative interviews and workshops with experts in government, academia, the military, and with HERO staff were reviewed critically by an expert technical advisory panel. Over 1600 participants contributed to curriculum development. Of the 18 competency domains identified as essential for HERO staff, nine were developed into priority in-service training modules to be conducted over 2.5 weeks. Experts from academia and experienced practitioners prepared and delivered each module through lectures followed by interactive problem-solving exercises and desktop simulations to help trainees apply, experiment with, and consolidate newly acquired knowledge and skills. This study adds to the emerging literature on China's enduring efforts to strengthen its emergency response capabilities since the outbreak of SARS in 2003. The multi-method approach to curriculum development in partnership with senior policy-makers, researchers, and experienced practitioners can be applied in other settings to ensure training is responsive and customized to local needs, resources and priorities. Ongoing curriculum development should reflect international standards and be coupled with the development of appropriate performance support systems at the workplace for motivating staff to apply their newly acquired knowledge and skills effectively and creatively.

  7. Association Between Manual Loading and Newly Developed Carpal Tunnel Syndrome in Subjects With Physical Disabilities: A Follow-Up Study.

    Science.gov (United States)

    Lin, Yen-Nung; Chiu, Chun-Chieh; Huang, Shih-Wei; Hsu, Wen-Yen; Liou, Tsan-Hon; Chen, Yi-Wen; Chang, Kwang-Hwa

    2017-10-01

    To identify the association between body composition and newly developed carpal tunnel syndrome (CTS) and to search for the best probabilistic cutoff value of associated factors to predict subjects with physical disabilities developing new CTS. Longitudinal. University-affiliated medical center. Subjects with physical disabilities (N=47; mean age ± SD, 42.1±7.7y). Not applicable. Median and ulnar sensory nerve conduction velocity (SNCV) were measured at the initial and follow-up tests (interval >2y). Total and regional body composition were measured with dual-energy x-ray absorptiometry at the initial test. Leg lean tissue percentage was calculated to delineate each participant's manual loading degree during locomotion. Leg lean tissue percentage is the lean tissue mass of both legs divided by body weight. Based on median SNCV changes, we divided all participants into 3 groups: subjects with bilateral CTS (median SNCV value normative ulnar SNCV value >37.8m/s) in the initial test (n=10), subjects with newly developed CTS in the follow-up test (n=8), and subjects without additional CTS in the follow-up test (n=27). Eight of 35 subjects not having bilateral CTS initially developed new CTS (8.8% per year; mean follow-up period, 2.6y). Leg lean tissue percentage was associated with the probability of newly developed CTS (adjusted odds ratio, .64; P12% were less likely to have developed new CTS at the follow-up test (sensitivity, .75; specificity, .85; area under the curve, .88; Pphysical disabilities. Therefore, a preventive program for those subjects at risk can start early. Copyright © 2017 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  8. A newly developed borehole flowmeter technology for heterogeneous aquifers

    International Nuclear Information System (INIS)

    Young, S.C.

    1990-01-01

    Extensive borehole flowmeter tests were performed at 37 fully-screened wells on a one-hectare test site to characterize the three-dimensional hydraulic conductivity field of an alluvial aquifer with a σ lnK of 4.7. During the site investigations, several major advancements with respect to borehole flowmeter technology were developed. The milestones included: (1) the development of a field-durable electromagnetic borehole flowmeter with a lower detection limit of 0.1 l/min; (2) the realization of the importance of the pumping rate with respect to the calculated value for the depth-averaged hydraulic conductivity; and (3) an evaluation of alternative methods for calculating the depth-averaged hydraulic conductivity. The predicted three-dimensional hydraulic conductivity field was compared to the results of 10 small-scale (3 to 7 m) tracer tests, information about the depositional history of the aquifer, and the results of three large-scale aquifer tests. The hydraulic conductivity data predict the major features of the tracer breakthrough curves, maps the outline of a former river meander in an aerial photograph, and leads to a geometric mean consistent with the average hydraulic conductivity of the aquifer. (Author) (14 refs., 15 figs., 2 tabs.)

  9. In vitro stent lumen visualisation of various common and newly developed femoral artery stents using MR angiography at 1.5 and 3 tesla.

    Science.gov (United States)

    Syha, R; Ketelsen, D; Kaempf, M; Mangold, S; Sixt, S; Zeller, T; Springer, F; Schick, F; Claussen, C D; Brechtel, K

    2013-02-01

    To evaluate stent lumen assessment of various commonly used and newly developed stents for the superficial femoral artery (SFA) using MR angiography (MRA) at 1.5 and 3 T. Eleven nitinol stents and one cobalt-chromium stent were compared regarding stent lumen visualisation using a common three-dimensional MRA sequence. Maximum visible stent lumen width and contrast ratio were analysed in three representative slices for each stent type. A scoring system for lumen visualisation was applied. Nitinol stents showed significantly better performance than the cobalt chromium stent (P stent lumen ranged between 43.4 and 95.5 %, contrast ratio between 7.2 and 110.6 %. Regarding both field strengths, seven of the nitinol stents were classified as "suitable". Three nitinol stents were "limited", and one nitinol stent and the cobalt chromium stent were "not suitable". Intraluminal loss of signal and artefacts of most of the SFA stents do not markedly limit assessment of stent lumen by MRA at 1.5 and 3 T. MRA can thus be considered a valid technique for detection of relevant in-stent restenosis. Applied field strength does not strongly influence stent lumen assessment in general, but proper choice of field strength might be helpful.

  10. Efficacy of Topical Therapy with Newly Developed Terbinafine and Econazole Formulations in the Treatment of Dermatophytosis in Cats.

    Science.gov (United States)

    Ivaskiene, M; Matusevicius, A P; Grigonis, A; Zamokas, G; Babickaite, L

    2016-09-01

    In the field of veterinary dermatology dermatophytosis is one of the most frequently occurring infectious diseases, therefore its treatment should be effective, convenient, safe and inexpensive. The aim of this study was to evaluate the efficacy of newly developed topical formulations in the treatment of cats with dermatophytosis. Evaluation of clinical efficacy and safety of terbinafine and econazole formulations administered topically twice a day was performed in 40 cats. Cats, suffering from the most widely spread Microsporum canis-induced dermatophytosis and treated with terbinafine hydrochloride 1% cream, recovered within 20.3±0.88 days; whereas when treated with econazole nitrate 1% cream, they recovered within 28.4±1.14 days. A positive therapeutic effect was yielded by combined treatment with local application of creams and whole coat spray with enilconazole 0.2% emulsion "Imaverol". Most cats treated with econazole cream revealed redness and irritation of the skin at the site of application. This study demonstrates that terbinafine tended to have superior clinical efficacy (p<0.001) in the treatment of dermatophytosis in cats compared to the azole tested.

  11. A newly developed Fe-doped calcium sulfide nanoparticles with magnetic property for cancer hyperthermia

    Science.gov (United States)

    Wu, Steven Yueh-Hsiu; Tseng, Ching-Li; Lin, Feng-Huei

    2010-05-01

    In this study, a magnetic iron-doped calcium sulfide (Fe-CaS) nanoparticle was newly developed and studied for the purpose of hyperthermia due to its promising magnetic property, adequate biodegradation rate, and relatively good biocompatibility. Fe-CaS nanoparticles were synthesized by a wet chemical co-precipitation process with heat treatment in a N2 atmosphere, and were subsequently cooled in N2 and exposed to air at a low temperature. The crystal structure of the Fe-CaS nanoparticles was similar to that of the CaS, which was identified by an X-ray diffractometer (XRD). The particle size was less than 40 nm based on a Debye-Scherrer equation and transmission electron microscope (TEM) examination. Magnetic properties obtained from the SQUID magnetometer demonstrated that the synthesized CaS was a diamagnetic property. Once the Fe ions were doped, the synthesized Fe-CaS converted into paramagnetism which showed no hysteresis loop. Having been heated above 600 °C in N2, the Fe-CaS showed a promising magnetic property to produce enough energy to increase the temperature for hyperthermia. 10 mg/ml of the Fe-CaS was able to generate heat to elevate the media temperature over 42.5 °C within 6 min. The area of the hysteresis loop increased with the increasing of the treated temperature, especially at 800 °C for 1 h. This is because more Fe ions replaced Ca ions in the lattice at the higher heat treatment temperature. The heat production was also increasing with the increasing of heat treatment temperature, which resulted in an adequate specific absorption ratio (SAR) value, which was found to be 45.47 W/g at 37 °C under an alternative magnetic field of f = 750 KHz , H = 10 Oe. The in vitro biocompatibility test of the synthesized Fe-CaS nanoparticles examined by the LDH assay showed no cytotoxicity to 3T3 fibroblast. The result of in vitro cell hyperthermia shows that under magnetic field the Fe-CaS nanoparticles were able to generate heat and kill the CT-26 cancer

  12. A newly developed Fe-doped calcium sulfide nanoparticles with magnetic property for cancer hyperthermia

    International Nuclear Information System (INIS)

    Wu, Steven Yueh-Hsiu; Tseng, Ching-Li; Lin, Feng-Huei

    2010-01-01

    In this study, a magnetic iron-doped calcium sulfide (Fe-CaS) nanoparticle was newly developed and studied for the purpose of hyperthermia due to its promising magnetic property, adequate biodegradation rate, and relatively good biocompatibility. Fe-CaS nanoparticles were synthesized by a wet chemical co-precipitation process with heat treatment in a N 2 atmosphere, and were subsequently cooled in N 2 and exposed to air at a low temperature. The crystal structure of the Fe-CaS nanoparticles was similar to that of the CaS, which was identified by an X-ray diffractometer (XRD). The particle size was less than 40 nm based on a Debye-Scherrer equation and transmission electron microscope (TEM) examination. Magnetic properties obtained from the SQUID magnetometer demonstrated that the synthesized CaS was a diamagnetic property. Once the Fe ions were doped, the synthesized Fe-CaS converted into paramagnetism which showed no hysteresis loop. Having been heated above 600 o C in N 2 , the Fe-CaS showed a promising magnetic property to produce enough energy to increase the temperature for hyperthermia. 10 mg/ml of the Fe-CaS was able to generate heat to elevate the media temperature over 42.5 o C within 6 min. The area of the hysteresis loop increased with the increasing of the treated temperature, especially at 800 o C for 1 h. This is because more Fe ions replaced Ca ions in the lattice at the higher heat treatment temperature. The heat production was also increasing with the increasing of heat treatment temperature, which resulted in an adequate specific absorption ratio (SAR) value, which was found to be 45.47 W/g at 37 o C under an alternative magnetic field of f = 750 KHz, H = 10 Oe. The in vitro biocompatibility test of the synthesized Fe-CaS nanoparticles examined by the LDH assay showed no cytotoxicity to 3T3 fibroblast. The result of in vitro cell hyperthermia shows that under magnetic field the Fe-CaS nanoparticles were able to generate heat and kill the CT-26

  13. Value of a newly sequenced bacterial genome

    DEFF Research Database (Denmark)

    Barbosa, Eudes; Aburjaile, Flavia F; Ramos, Rommel Tj

    2014-01-01

    and annotation will not be undertaken. It is important to know what is lost when we settle for a draft genome and to determine the "scientific value" of a newly sequenced genome. This review addresses the expected impact of newly sequenced genomes on antibacterial discovery and vaccinology. Also, it discusses...... heightened expectations that NGS would boost antibacterial discovery and vaccine development. Although many possible drug and vaccine targets have been discovered, the success rate of genome-based analysis has remained below expectations. Furthermore, NGS has had consequences for genome quality, resulting...

  14. Underground trials on a newly developed EDW 150-2 L unit

    Energy Technology Data Exchange (ETDEWEB)

    Wille, G.; Klimek, K.H.

    1982-01-01

    Coal-getting from medium thick coalbeds (> 1.7 m) requires high-performance shearer-loaders. Machine length and adjustability have to be such as to permit smooth cutting through geological faults. Furthermore they should be suitable to cut out niches for the AFC drives so that gateroads can be driven along with the face line. The newly developed EDW 150-2 L shearer-loader meets these expectations after various mechanical and electrical improvements. The unit proved its usefulness from the beginning and in the most difficult geological conditions where other shearer-loaders normally available for the range of coalbed thickness would mostly have failed. The multiple requirements and disturbances have led to a number of separate improvements and disturbances have led to a number of separate improvements which together contribute to a basic improvement of the machine concept as far as applications, operational flexibility and safety are concerned.

  15. The $16,819 pay gap for newly trained physicians: the unexplained trend of men earning more than women.

    Science.gov (United States)

    Lo Sasso, Anthony T; Richards, Michael R; Chou, Chiu-Fang; Gerber, Susan E

    2011-02-01

    Prior research has suggested that gender differences in physicians' salaries can be accounted for by the tendency of women to enter primary care fields and work fewer hours. However, in examining starting salaries by gender of physicians leaving residency programs in New York State during 1999-2008, we found a significant gender gap that cannot be explained by specialty choice, practice setting, work hours, or other characteristics. The unexplained trend toward diverging salaries appears to be a recent development that is growing over time. In 2008, male physicians newly trained in New York State made on average $16,819 more than newly trained female physicians, compared to a $3,600 difference in 1999.

  16. Tripolar electric field Structure in guide field magnetic reconnection

    Science.gov (United States)

    Fu, Song; Huang, Shiyong; Zhou, Meng; Ni, Binbin; Deng, Xiaohua

    2018-03-01

    It has been shown that the guide field substantially modifies the structure of the reconnection layer. For instance, the Hall magnetic and electric fields are distorted in guide field reconnection compared to reconnection without guide fields (i.e., anti-parallel reconnection). In this paper, we performed 2.5-D electromagnetic full particle simulation to study the electric field structures in magnetic reconnection under different initial guide fields (Bg). Once the amplitude of a guide field exceeds 0.3 times the asymptotic magnetic field B0, the traditional bipolar Hall electric field is clearly replaced by a tripolar electric field, which consists of a newly emerged electric field and the bipolar Hall electric field. The newly emerged electric field is a convective electric field about one ion inertial length away from the neutral sheet. It arises from the disappearance of the Hall electric field due to the substantial modification of the magnetic field and electric current by the imposed guide field. The peak magnitude of this new electric field increases linearly with the increment of guide field strength. Possible applications of these results to space observations are also discussed.

  17. Tripolar electric field Structure in guide field magnetic reconnection

    Directory of Open Access Journals (Sweden)

    S. Fu

    2018-03-01

    Full Text Available It has been shown that the guide field substantially modifies the structure of the reconnection layer. For instance, the Hall magnetic and electric fields are distorted in guide field reconnection compared to reconnection without guide fields (i.e., anti-parallel reconnection. In this paper, we performed 2.5-D electromagnetic full particle simulation to study the electric field structures in magnetic reconnection under different initial guide fields (Bg. Once the amplitude of a guide field exceeds 0.3 times the asymptotic magnetic field B0, the traditional bipolar Hall electric field is clearly replaced by a tripolar electric field, which consists of a newly emerged electric field and the bipolar Hall electric field. The newly emerged electric field is a convective electric field about one ion inertial length away from the neutral sheet. It arises from the disappearance of the Hall electric field due to the substantial modification of the magnetic field and electric current by the imposed guide field. The peak magnitude of this new electric field increases linearly with the increment of guide field strength. Possible applications of these results to space observations are also discussed.

  18. A Newly Improved Modified Method Development and Validation of Bromofenac Sodium Sesquihydrate in Bulk Drug Manufacturing

    OpenAIRE

    Sunil Kumar Yelamanchi V; Useni Reddy Mallu; I. V Kasi Viswanath; D. Balasubramanyam; G. Narshima Murthy

    2016-01-01

    The main objective of this study was to develop a simple, efficient, specific, precise and accurate newly improved modified Reverse Phase High Performance Liquid Chromatographic Purity (or) Related substance method for bromofenac sodium sesquihydrate active pharmaceuticals ingredient dosage form. Validation of analytical method is the confirmation by examination and the provision of objective evidence that the particular requirements for a specific intended use are fulfilled as per ICH, USP...

  19. A Newly Developed Nested PCR Assay for the Detection of Helicobacter pylori in the Oral Cavity.

    Science.gov (United States)

    Ismail, Hawazen; Morgan, Claire; Griffiths, Paul; Williams, John; Jenkins, Gareth

    2016-01-01

    To develop a new nested polymerase chain reaction (PCR) assay for identifying Helicobacter pylori DNA from dental plaque. H. pylori is one of the most common chronic bacterial pathogens in humans. The accurate detection of this organism is essential for proper patient management and for the eradication of the bacteria following treatment. Forty-nine patients (24 males and 25 females; mean age: 51; range, 19 to 94 y) were investigated for the presence of H. pylori in dental plaque by single-step PCR and nested PCR and in the stomach by single-step PCR, nested PCR, and histologic examination. The newly developed nested PCR assay identified H. pylori DNA in gastric biopsies of 18 patients who were histologically classified as H. pylori-positive and 2 additional biopsies of patients who were H. pylori-negative by histologic examination (20/49; 40.8%). Dental plaque samples collected before and after endoscopy from the 49 patients revealed that single-step PCR did not detect H. pylori but nested PCR was able to detect H. pylori DNA in 40.8% (20/49) patients. Nested PCR gave a higher detection rate (40.8%, 20/49) than that of histology (36.7%, 18/49) and single-step PCR. When nested PCR results were compared with histology results there was no significant difference between the 2 methods. Our newly developed nested PCR assay is at least as sensitive as histology and may be useful for H. pylori detection in patients unfit for endoscopic examination.

  20. Characteristics of bread prepared from wheat flours blended with various kinds of newly developed rice flours.

    Science.gov (United States)

    Nakamura, S; Suzuki, K; Ohtsubo, K

    2009-04-01

    Characteristics of the bread prepared from wheat flour blended with the flour of various kinds of newly developed rice cultivars were investigated. Qualities of the bread made from wheat flour blended with rice flour have been reported to be inferior to those from 100% wheat flour bread. To improve its qualities, we searched for the new-characteristic rice flours among the various kinds of newly developed rice cultivars to blend with the wheat flour for the bread preparation. The most suitable new characteristic rices are combination of purple waxy rice, high-amylose rice, and sugary rice. Specific volume of the bread from the combination of wheat and these 3 kinds of rice flours showed higher specific volume (3.93) compared with the traditional wheat/rice bread (3.58). We adopted the novel method, continuous progressive compression test, to measure the physical properties of the dough and the bread in addition to the sensory evaluation. As a result of the selection of the most suitable rice cultivars and blending ratio with the wheat flour, we could develop the novel wheat/rice bread, of which loaf volume, physical properties, and tastes are acceptable and resistant to firming on even 4 d after the bread preparation. To increase the ratio of rice to wheat, we tried to add a part of rice as cooked rice grains. The specific volume and qualities of the bread were maintained well although the rice content of total flour increased from 30% to 40%.

  1. The construction of social identity in newly recruited nuclear engineering staff: A longitudinal study

    International Nuclear Information System (INIS)

    Nguyen, Lynda; Murphy, Glen; Chang, Artemis

    2014-01-01

    This study examines the process by which newly recruited nuclear engineering and technical staff came to understand, define, think, feel and behave within a distinct group that has a direct contribution to the organization's overall emphasis on a culture of reliability and system safety. In the field of organizational behavior the interactive model of social identity formation has been recently proposed to explain the process by which the internalization of shared norms and values occurs, an element critical in identity formation. Using this rich model of organizational behavior we analyzed multiple sources of data from nine new hires over a period of three years. This was done from the time they were employed to investigate the construction of social identity by new entrants entering into a complex organizational setting reflected in the context of a nuclear facility. Informed by our data analyses, we found support for the interactive model of social identity development and report the unexpected finding that a newly appointed member's age and level of experience appears to influence the manner in which they adapt, and assimilate into their surroundings. This study represents an important contribution to the safety and reliability literature as it provides a rich insight into the way newly recruited employees enact the process by which their identities are formed and hence act, particularly under conditions of duress or significant organizational disruption in complex organizational settings. - Highlights: • We examined how newly recruited nuclear engineer staff develop their social identity. • The study empirically examined the interactive model of social identity formation. • Innovative research strategies were used to capture rich primary data for all case studies. • Age and experience moderated internalization route and the social identity formation process

  2. Neurobehavioural methods, effects and prevention: workers' human rights are why the field matters for developing countries.

    Science.gov (United States)

    London, L

    2009-11-01

    Little research into neurobehavioural methods and effects occurs in developing countries, where established neurotoxic chemicals continue to pose significant occupational and environmental burdens, and where agents newly identified as neurotoxic are also widespread. Much of the morbidity and mortality associated with neurotoxic agents remains hidden in developing countries as a result of poor case detection, lack of skilled personnel, facilities and equipment for diagnosis, inadequate information systems, limited resources for research and significant competing causes of ill-health, such as HIV/AIDS and malaria. Placing the problem in a human rights context enables researchers and scientists in developing countries to make a strong case for why the field of neurobehavioural methods and effects matters because there are numerous international human rights commitments that make occupational and environmental health and safety a human rights obligation.

  3. Challenges on innovations of newly-developed safety analysis codes

    International Nuclear Information System (INIS)

    Yang, Yanhua; Zhang, Hao

    2016-01-01

    With the development of safety analysis method, the safety analysis codes meet more challenges. Three challenges are presented in this paper, which are mathematic model, code design and user interface. Combined with the self-reliance safety analysis code named COSINE, the ways of meeting these requirements are suggested, that is to develop multi-phases, multi-fields and multi-dimension models, to adopt object-oriented code design ideal and to improve the way of modeling, calculation control and data post-processing in the user interface.

  4. Challenges on innovations of newly-developed safety analysis codes

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Yanhua [Shanghai Jiao Tong Univ. (China). School of Nuclear Science and Engineering; Zhang, Hao [State Nuclear Power Software Development Center, Beijing (China). Beijing Future Science and Technology City

    2016-05-15

    With the development of safety analysis method, the safety analysis codes meet more challenges. Three challenges are presented in this paper, which are mathematic model, code design and user interface. Combined with the self-reliance safety analysis code named COSINE, the ways of meeting these requirements are suggested, that is to develop multi-phases, multi-fields and multi-dimension models, to adopt object-oriented code design ideal and to improve the way of modeling, calculation control and data post-processing in the user interface.

  5. Field-aligned currents during northward interplanetary magnetic field: Morphology and causes

    DEFF Research Database (Denmark)

    Vennerstrøm, Susanne; Moretto, T.; Rastatter, L.

    2005-01-01

    [1] We present the results of a global MHD simulation of solar wind magnetosphere interaction during northward IMF. In particular, we emphasize the effect of the IMF By component on the reconnection geometry and the mapping along field lines to the polar ionosphere, through field-aligned currents....... We find that the existence and geometry of the polar cap is closely connected to the IMF By component. During strictly northward IMF the simulated magnetosphere can remain essentially closed because the solar wind field lines reconnect in both hemispheres, thereby creating newly reconnected closed...... both on open and closed field lines and are created by the shear of the newly reconnected field lines against the mantle field as they are convected tailward by the solar wind. When the IMF rotates from northward toward east, the magnetospheric mapping regions of the NBZ currents likewise rotates...

  6. The effectiveness of newly developed written asthma action plan in improvement of asthma outcome in children.

    Science.gov (United States)

    Lakupoch, Kingthong; Manuyakorn, Wiparat; Preutthipan, Aroonwan; Kamalaporn, Harutai

    2017-09-17

    Providing asthma education about controller medication use and appropriate management of asthma exacerbation are the keys to improving the disease outcome. Many asthma guidelines recommend that physicians provide written asthma action plan (WAAP) to all of their asthmatic patients. However, the benefit of WAAP is unclear. Thus, we have created a new WAAP which is simplified in Thai and more user friendly. To determine the effectiveness of the newly developed asthma action plan in management of children with asthma. Asthmatic children who meet inclusion criteria all received the WAAP and they were followed up for 6 months with measurement of outcome variables, such as asthma exacerbation that required emergency room visit, unscheduled OPD visit, admission and school absence in order to compare with the past 6 months before receiving the WAAP. The analyzed outcomes of forty-nine children show significantly reduced emergency room visit (P-value 0.005), unscheduled OPD visit (P-value 0.046), admission days (P-value 0.026) and school absence days (P-value 0.022). Well controlled group and mild severity group were not the factors that contribute to decreased emergency room visit but step up therapy may be the co-factor to decreased ER visit. The results of this study suggest that the provision of newly developed WAAP is useful for improving self-care of asthma patients and reducing asthma exacerbation.

  7. System studies in PA: Development of process influence diagram (PID) for SFR-1 repository near-field + far-field

    International Nuclear Information System (INIS)

    Stenhouse, M.J.; Miller, W.M.; Chapman, N.A.

    2001-05-01

    Scenario development is a key component of the performance assessment (PA) process for radioactive waste disposal, the primary objective being to ensure that all relevant factors associated with the future evolution of the repository system are properly considered in PA. As part of scenario development, a list of features, events and processes (FEPs) are identified and assembled, representing the Process System, with interactions/influences between FEPs incorporated in a Process Influence Diagram (PID). This report documents the technical work conducted between 1997 and the end of 1999 under the Systems Studies Project. The overall objective of this project has been the construction of a PID for the SFR-1 repository (final repository for reactor waste), this PID being the first stage in the identification of scenarios to describe future evolution of this repository. The PIDs discussed in this report have been created using two software applications: existing commercial software (Business Modeller, Infotool AB. Stockholm, Sweden) and, more recently, a newly developed software tool SPARTA (Enviros QuantiSci, Henley, U.K.). Although the focus of this report is on the application of SPARTA to PID development, it is important to document the work carried out prior to SPARTA being available, in order to provide a complete record of the entire SFR-1 PID development effort as well as preserving the context of the multi-year project. Following a description of the different disposal sections of the SFR-1 and the various near-field barriers, the sequential development (i.e. near-field of Silo, BMA, BLA, BTF sections; far-field; integrated near-field + far-field) of the PID for SFR-1 repository system using Business Modeller is described. Owing to the complexity of the repository, in terms of number of both different disposal sections (Silo, BLA, BMA, BTF) and barriers associated with each section, the two-dimensional (2D) PID created for SFR-1 using Business Modeller is

  8. SU-E-T-225: Correction Matrix for PinPoint Ionization Chamber for Dosimetric Measurements in the Newly Released Incise™ Multileaf Collimator Shaped Small Field for CyberKnife M6™ Machine

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Y; Li, T; Heron, D; Huq, M [University of Pittsburgh Cancer Institute and UPMC CancerCenter, Pittsburgh, PA (United States)

    2015-06-15

    Purpose: For small field dosimetry, such as measurements of output factors for cones or MLC-shaped irregular small fields, ion chambers often Result in an underestimation of the dose, due to both the volume averaging effect and the lack of lateral charged particle equilibrium. This work presents a mathematical model for correction matrix for a PTW PinPoint ionization chamber for dosimetric measurements made in the newly released Incise™ Multileaf collimator fields of the CyberKnife M6™ machine. Methods: A correction matrix for a PTW 0.015cc PinPoint ionization chamber was developed by modeling its 3D dose response in twelve cone-shaped circular fields created using the 5mm, 7.5mm, 10mm, 12.5mm, 15mm, 20mm, 25mm, 30mm, 35mm, 40mm, 50mm, 60mm cones in a CyberKnife M6™ machine. For each field size, hundreds of readings were recorded for every 2mm chamber shift in the horizontal plane. The contribution of each dose pixel to a measurement point depended on the radial distance and the angle to the chamber axis. These readings were then compared with the theoretical dose as obtained with Monte Carlo calculation. A penalized least-square optimization algorithm was developed to generate the correction matrix. After the parameter fitting, the mathematical model was validated for MLC-shaped irregular fields. Results: The optimization algorithm used for parameter fitting was stable and the resulted response factors were smooth in spatial domain. After correction with the mathematical model, the chamber reading matched with the calculation for all the tested fields to within 2%. Conclusion: A novel mathematical model has been developed for PinPoint chamber for dosimetric measurements in small MLC-shaped irregular fields. The correction matrix is dependent on detector, treatment unit and the geometry of setup. The model can be applied to non-standard composite fields and provides an access to IMRT point dose validation.

  9. SU-E-T-225: Correction Matrix for PinPoint Ionization Chamber for Dosimetric Measurements in the Newly Released Incise™ Multileaf Collimator Shaped Small Field for CyberKnife M6™ Machine

    International Nuclear Information System (INIS)

    Zhang, Y; Li, T; Heron, D; Huq, M

    2015-01-01

    Purpose: For small field dosimetry, such as measurements of output factors for cones or MLC-shaped irregular small fields, ion chambers often Result in an underestimation of the dose, due to both the volume averaging effect and the lack of lateral charged particle equilibrium. This work presents a mathematical model for correction matrix for a PTW PinPoint ionization chamber for dosimetric measurements made in the newly released Incise™ Multileaf collimator fields of the CyberKnife M6™ machine. Methods: A correction matrix for a PTW 0.015cc PinPoint ionization chamber was developed by modeling its 3D dose response in twelve cone-shaped circular fields created using the 5mm, 7.5mm, 10mm, 12.5mm, 15mm, 20mm, 25mm, 30mm, 35mm, 40mm, 50mm, 60mm cones in a CyberKnife M6™ machine. For each field size, hundreds of readings were recorded for every 2mm chamber shift in the horizontal plane. The contribution of each dose pixel to a measurement point depended on the radial distance and the angle to the chamber axis. These readings were then compared with the theoretical dose as obtained with Monte Carlo calculation. A penalized least-square optimization algorithm was developed to generate the correction matrix. After the parameter fitting, the mathematical model was validated for MLC-shaped irregular fields. Results: The optimization algorithm used for parameter fitting was stable and the resulted response factors were smooth in spatial domain. After correction with the mathematical model, the chamber reading matched with the calculation for all the tested fields to within 2%. Conclusion: A novel mathematical model has been developed for PinPoint chamber for dosimetric measurements in small MLC-shaped irregular fields. The correction matrix is dependent on detector, treatment unit and the geometry of setup. The model can be applied to non-standard composite fields and provides an access to IMRT point dose validation

  10. Conventional and improved cytotoxicity test methods of newly developed biodegradable magnesium alloys

    Science.gov (United States)

    Han, Hyung-Seop; Kim, Hee-Kyoung; Kim, Yu-Chan; Seok, Hyun-Kwang; Kim, Young-Yul

    2015-11-01

    Unique biodegradable property of magnesium has spawned countless studies to develop ideal biodegradable orthopedic implant materials in the last decade. However, due to the rapid pH change and extensive amount of hydrogen gas generated during biocorrosion, it is extremely difficult to determine the accurate cytotoxicity of newly developed magnesium alloys using the existing methods. Herein, we report a new method to accurately determine the cytotoxicity of magnesium alloys with varying corrosion rate while taking in-vivo condition into the consideration. For conventional method, extract quantities of each metal ion were determined using ICP-MS and the result showed that the cytotoxicity due to pH change caused by corrosion affected the cell viability rather than the intrinsic cytotoxicity of magnesium alloy. In physiological environment, pH is regulated and adjusted within normal pH (˜7.4) range by homeostasis. Two new methods using pH buffered extracts were proposed and performed to show that environmental buffering effect of pH, dilution of the extract, and the regulation of eluate surface area must be taken into consideration for accurate cytotoxicity measurement of biodegradable magnesium alloys.

  11. Evaluation of Shielding Performance for Newly Developed Composite Materials

    Science.gov (United States)

    Evans, Beren Richard

    This work details an investigation into the contributing factors behind the success of newly developed composite neutron shield materials. Monte Carlo simulation methods were utilized to assess the neutron shielding capabilities and secondary radiation production characteristics of aluminum boron carbide, tungsten boron carbide, bismuth borosilicate glass, and Metathene within various neutron energy spectra. Shielding performance and secondary radiation data suggested that tungsten boron carbide was the most effective composite material. An analysis of the macroscopic cross-section contributions from constituent materials and interaction mechanisms was then performed in an attempt to determine the reasons for tungsten boron carbide's success over the other investigated materials. This analysis determined that there was a positive correlation between a non-elastic interaction contribution towards a material's total cross-section and shielding performance within the thermal and epi-thermal energy regimes. This finding was assumed to be a result of the boron-10 absorption reaction. The analysis also determined that within the faster energy regions, materials featuring higher non-elastic interaction contributions were comparable to those exhibiting primarily elastic scattering via low Z elements. This allowed for the conclusion that composite shield success within higher energy neutron spectra does not necessitate the use elastic scattering via low Z elements. These findings suggest that the inclusion of materials featuring high thermal absorption properties is more critical to composite neutron shield performance than the presence of constituent materials more inclined to maximize elastic scattering energy loss.

  12. Combustion, performance and emissions characteristics of a newly ...

    Indian Academy of Sciences (India)

    of a newly developed CRDI single cylinder diesel engine. AVINASH ... In case of unit injector and unit pump systems, fuel injection pressure depends on ... nozzle hole diameters were effective in reducing smoke and PM emissions. However ...

  13. The use of newly developed real-time PCR for the rapid identification of bacteria in culture-negative osteomyelitis.

    Science.gov (United States)

    Kobayashi, Naomi; Bauer, Thomas W; Sakai, Hiroshige; Togawa, Daisuke; Lieberman, Isador H; Fujishiro, Takaaki; Procop, Gary W

    2006-12-01

    We report a case of a culture-negative osteomyelitis in which our newly developed real-time polymerase chain reaction (PCR) could differentiate Staphylococcus aureus from Staphylococcus epidermidis. This is the first report that described the application of this novel assay to an orthopedics clinical sample. This assay may be useful for other clinical culture-negative cases in a combination with a broad-spectrum assay as a rapid microorganism identification method.

  14. Perceptions of the clinical competence of newly registered nurses in the North West province

    Directory of Open Access Journals (Sweden)

    M.R. Moeti

    2004-09-01

    Full Text Available The clinical competence of newly registered nurses relating to the care of individual Clients, depends on their ability to correlate theoretical knowledge learned in the classroom with practice and the development of clinical skills. Its foundation lies in the ability to identify and solve problems that emanate from critical thinking, analytical reasoning and reflective practice. It is clear that the quality of clinical exposure plays a leading role in the development of nursing professionals. Nursing skills alone cannot ensure quality care of clients without the application of theory. Facilitation of this theory to practice therefore remains an essential component of nursing education. This study was aimed at identifying areas of incompetence of newly registered nurses (1998- 2001 in the clinical area by determining the newly registered nurses1 and professional nurses1 perceptions of the competence of the newly registered nurses. A quantitative, non-experimental, descriptive survey was used to collect the data regarding the clinical competence of newly registered nurses (1998-2001.

  15. Measurement equivalence of the newly developed Quality of Life in Childhood Epilepsy Questionnaire (QOLCE-55).

    Science.gov (United States)

    Ferro, Mark A; Goodwin, Shane W; Sabaz, Mark; Speechley, Kathy N

    2016-03-01

    The aim of this study was to examine measurement equivalence of the newly developed Quality of Life in Childhood Epilepsy Questionnaire (QOLCE-55) across age, sex, and time in a representative sample of children with newly diagnosed epilepsy. Data come from 373 children enrolled in the Health-related Quality of Life in Children with Epilepsy Study (HERQULES), a multisite prospective cohort study. Measurement equivalence was examined using a multiple-group confirmatory factor analysis framework, whereby increasingly stringent parameter constraints are imposed on the model. Comparison groups were stratified based on age (4-7 years vs. 8-12 years), sex (male vs. female), and time (measurement of health-related quality of life at diagnosis vs. 24 months later). The QOLCE-55 demonstrated measurement equivalence at the level of strict invariance for each model tested--age: χ(2) (3,123) = 4,097.3, p QOLCE-55 are perceived similarly among groups stratified by age, sex, and time and provide further evidence supporting the validity of the scale in children with epilepsy. Health professionals and researchers should be confident that group comparisons made using the QOLCE-55 are unbiased and that any group differences detected are meaningful; that is, not related to differences in the interpretation of items by informants. Future research replicating these findings is encouraged. Wiley Periodicals, Inc. © 2016 International League Against Epilepsy.

  16. Practicing on Newly Dead

    Directory of Open Access Journals (Sweden)

    Jewel Abraham

    2015-07-01

    Full Text Available A newly dead cadaver simulation is practiced on the physical remains of the dead before the onset of rigor mortis. This technique has potential benefits for providing real-life in-situ experience for novice providers in health care practices. Evolving ethical views in health care brings into question some of the ethical aspects associated with newly dead cadaver simulation in terms of justification for practice, autonomy, consent, and the need of disclosure. A clear statement of policies and procedures on newly dead cadaver simulation has yet to be implemented. Although there are benefits and disadvantages to an in-situ cadaver simulation, such practices should not be carried out in secrecy as there is no compelling evidence that suggests such training as imperative. Secrecy in these practices is a violation of honor code of nursing ethics. As health care providers, practitioners are obliged to be ethically honest and trustworthy to their patients. The author explores the ethical aspects of using newly dead cadaver simulation in training novice nursing providers to gain competency in various lifesaving skills, which otherwise cannot be practiced on a living individual. The author explores multiple views on cadaver simulation in relation to ethical theories and practices such as consent and disclosure to family.

  17. Newly qualified teachers´ possibilities to get foothold in a lifelong career course

    DEFF Research Database (Denmark)

    Krøjgaard, Frede; Frederiksen, Lisbeth Angela Lunde

    Keyword: Induction program, newly qualified teachers, NQT, retention, professional development In Contrary to many other countries in Europe Denmark does not have any kind of national program regarding teacher induction program (TIP) or support in general to newly qualified teachers what so ever...

  18. Effect of weed control methods on some soil properties of a newly ...

    African Journals Online (AJOL)

    Weed control constitutes a high percentage of the total field maintenance cost of newly planted cocoa. Soil samples were collected from an experiment that was designed to evaluate some weed control methods during cocoa establishment. The objective of the experiment was to assess the effect of the weed control ...

  19. The practical skills of newly qualified nurses.

    Science.gov (United States)

    Danbjørg, Dorthe Boe; Birkelund, Regner

    2011-02-01

    This paper reports the findings from a study of newly qualified nurses and which subjects the nurses regarded as the most important in order to be able to live up to the requirements of clinical practice, and how they experience their potential for developing practical and moral skills, after the decrease in practical training. A qualitative approach guided the research process and the analysis of the data. The data was collected by participant observation and qualitative interviews with four nurses as informants. The conclusions made in this study are based on the statements and the observations of the newly qualified nurses. Our findings are discussed in relation to the Aristotelian concept and other relevant literature. The main message is that the newly qualified nurses did not feel equipped when they finished their training. This could be interpreted as a direct consequence of the decrease in practical training. Our study also underlines that the way nursing theory is perceived and taught is problematic. The interviews revealed that the nurses think that nursing theories should be applied directly in practice. This misunderstanding is probably also applicable to the teachers of the theories. Copyright © 2010 Elsevier Ltd. All rights reserved.

  20. Comparison of newly developed anti-bone morphogenetic protein 4 llama-derived antibodies with commercially available BMP4 inhibitors.

    Science.gov (United States)

    Calpe, Silvia; Correia, Ana C P; Sancho-Serra, Maria Del Carmen; Krishnadath, Kausilia K

    2016-01-01

    Due to improved understanding of the role of bone morphogenetic protein 4 (BMP4) in an increasing number of diseases, the development of selective inhibitors of BMP4 is an attractive therapeutic option. The currently available BMP4 inhibitors are not suitable as therapeutics because of their low specificity and low effectiveness. Here, we compared newly generated anti-BMP4 llama-derived antibodies (VHHs) with 3 different types of commercially available BMP4 inhibitors, natural antagonists, small molecule BMPR inhibitors and conventional anti-BMP4 monoclonal antibodies. We found that the anti-BMP4 VHHs were as effective as the natural antagonist or small molecule inhibitors, but had higher specificity. We also showed that commercial anti-BMP4 antibodies were inferior in terms of both specificity and effectiveness. These findings might result from the fact that the VHHs C4C4 and C8C8 target a small region within the BMPR1 epitope of BMP4, whereas the commercial antibodies target other areas of the BMP4 molecule. Our results show that the newly developed anti-BMP4 VHHs are promising antibodies with better specificity and effectivity for inhibition of BMP4, making them an attractive tool for research and for therapeutic applications.

  1. Development of a framework for identification of political environmental issues faced by multinational hotel chains in newly industrialized countries in Asia

    OpenAIRE

    Kim, Chol Yong

    1992-01-01

    The primary/objective of this study was to develop a framework for identification of political environmental issues faced by multinational hotel chains in newly industrialized countries in Asia. To accomplish the objective, key factors having an impact upon these hotel chains were identified using the Delphi Technique.

  2. System studies in PA: Development of process influence diagram (PID) for SFR-1 repository near-field + far-field

    Energy Technology Data Exchange (ETDEWEB)

    Stenhouse, M.J. [Monitor Scientific, LLC, Denver, CO (United States); Miller, W.M.; Chapman, N.A. [QuantiSci Ltd., Melton Mowbray (United Kingdom)

    2001-05-01

    Scenario development is a key component of the performance assessment (PA) process for radioactive waste disposal, the primary objective being to ensure that all relevant factors associated with the future evolution of the repository system are properly considered in PA. As part of scenario development, a list of features, events and processes (FEPs) are identified and assembled, representing the Process System, with interactions/influences between FEPs incorporated in a Process Influence Diagram (PID). This report documents the technical work conducted between 1997 and the end of 1999 under the Systems Studies Project. The overall objective of this project has been the construction of a PID for the SFR-1 repository (final repository for reactor waste), this PID being the first stage in the identification of scenarios to describe future evolution of this repository. The PIDs discussed in this report have been created using two software applications: existing commercial software (Business Modeller, Infotool AB. Stockholm, Sweden) and, more recently, a newly developed software tool SPARTA (Enviros QuantiSci, Henley, U.K.). Although the focus of this report is on the application of SPARTA to PID development, it is important to document the work carried out prior to SPARTA being available, in order to provide a complete record of the entire SFR-1 PID development effort as well as preserving the context of the multi-year project. Following a description of the different disposal sections of the SFR-1 and the various near-field barriers, the sequential development (i.e. near-field of Silo, BMA, BLA, BTF sections; far-field; integrated near-field + far-field) of the PID for SFR-1 repository system using Business Modeller is described. Owing to the complexity of the repository, in terms of number of both different disposal sections (Silo, BLA, BMA, BTF) and barriers associated with each section, the two-dimensional (2D) PID created for SFR-1 using Business Modeller is

  3. Electron transport in the stochastic fields of RFP ZT-40M

    International Nuclear Information System (INIS)

    Punjabi, A.; Verma, A.; Kim, Myung-Hee; Boozer, A.

    1991-01-01

    In this paper, we use our newly developed Monte Carlo Method to study the transport of electrons in stochastic magnetic fields of the device RFP ZT4OM. The results of this calculation will be compared with the Rechester-Rosenbluth scaling

  4. Newly developed surface coil for endoluminal MRI, depiction of pig gastric wall layers and vascular architecture in ex vivo study.

    Science.gov (United States)

    Morita, Yoshinori; Kutsumi, Hiromu; Yoshinaka, Hayato; Matsuoka, Yuichiro; Kuroda, Kagayaki; Gotanda, Masakazu; Sekino, Naomi; Kumamoto, Etsuko; Yoshida, Masaru; Inokuchi, Hideto; Azuma, Takeshi

    2009-01-01

    The purpose of this study was to visualize the gastric wall layers and to depict the vascular architecture in vitro by using resected porcine stomachs studied with high-spatial resolution magnetic resonance (MR) imaging. Normal dissected porcine stomach samples (n = 4) were examined with a 3 Tesla MR system using a newly developed surface coil. MR images were obtained by the surface coil as receiver and a head coil as transmitter. High-spatial-resolution spin-echo MR images were obtained with a field of view of 8 x 8 cm, a matrix of 256 x 128 and slice thicknesses of 3 and 5 mm. T1 and T2-weighted MR images clearly depicted the normal porcine gastric walls as consisting of four distinct layers. In addition, vascular architectures in proper muscle layers were also visualized, which were confirmed by histological examinations to correspond to blood vessels. High-spatial-resolution MR imaging using a surface coil placed closely to the gastric wall enabled the differentiation of porcine gastric wall layers and the depiction of the blood vessels in proper muscle layer in this experimental study.

  5. Newly developed surface coil for endoluminal MRI, depiction of pig gastric wall layers and vascular architecture in ex vivo study

    International Nuclear Information System (INIS)

    Morita, Yoshinori; Kutsumi, Hiromu; Yoshinaka, Hayato

    2009-01-01

    The purpose of this study was to visualize the gastric wall layers and to depict the vascular architecture in vitro by using resected porcine stomachs studied with high-spatial resolution magnetic resonance (MR) imaging. Normal dissected porcine stomach samples (n=4) were examined with a 3 Tesla MR system using a newly developed surface coil. MR images were obtained by the surface coil as receiver and a head coil as transmitter. High-spatial-resolution spin-echo MR images were obtained with a field of view of 8 x 8 cm, a matrix of 256 x 128 and slice thicknesses of 3 and 5 mm. T1 and T2-weighted MR images clearly depicted the normal porcine gastric walls as consisting of four distinct layers. In addition, vascular architectures in proper muscle layers were also visualized, which were confirmed by histological examinations to correspond to blood vessels. High-spatial-resolution MR imaging using a surface coil placed closely to the gastric wall enabled the differentiation of porcine gastric wall layers and the depiction of the blood vessels in proper muscle layer in this experimental study. (author)

  6. Floating production platforms and their applications in the development of oil and gas fields in the South China Sea

    Science.gov (United States)

    Zhang, Dagang; Chen, Yongjun; Zhang, Tianyu

    2014-03-01

    This paper studies the current available options for floating production platforms in developing deepwater oil fields and the potential development models of future oil and gas exploration in the South China Sea. A detailed review of current deepwater platforms worldwide was performed through the examples of industry projects, and the pros and cons of each platform are discussed. Four types of platforms are currently used for the deepwater development: tension leg platform, Spar, semi-submersible platform, and the floating production system offloading. Among these, the TLP and Spar can be used for dry tree applications, and have gained popularity in recent years. The dry tree application enables the extension of the drilling application for fixed platforms into floating systems, and greatly reduces the cost and complexity of the subsea operation. Newly built wet tree semi-submersible production platforms for ultra deepwater are also getting their application, mainly due to the much needed payload for deepwater making the conversion of the old drilling semi-submersible platforms impossible. These platforms have been used in different fields around the world for different environments; each has its own advantages and disadvantages. There are many challenges with the successful use of these floating platforms. A lot of lessons have been learned and extensive experience accumulated through the many project applications. Key technologies are being reviewed for the successful use of floating platforms for field development, and potential future development needs are being discussed. Some of the technologies and experience of platform applications can be well used for the development of the South China Sea oil and gas field.

  7. Newly graduated nurses' use of knowledge sources

    DEFF Research Database (Denmark)

    Voldbjerg, Siri Lygum; Grønkjaer, Mette; Sørensen, Erik Elgaard

    2016-01-01

    AIM: To advance evidence on newly graduated nurses' use of knowledge sources. BACKGROUND: Clinical decisions need to be evidence-based and understanding the knowledge sources that newly graduated nurses use will inform both education and practice. Qualitative studies on newly graduated nurses' use...... underscoring progression in knowledge use and perception of competence and confidence among newly graduated nurses. CONCLUSION: The transition phase, feeling of confidence and ability to use critical thinking and reflection, has a great impact on knowledge sources incorporated in clinical decisions....... The synthesis accentuates that for use of newly graduated nurses' qualifications and skills in evidence-based practice, clinical practice needs to provide a supportive environment which nurtures critical thinking and questions and articulates use of multiple knowledge sources....

  8. Being a team leader: newly registered nurses relate their experiences.

    Science.gov (United States)

    Ekström, Louise; Idvall, Ewa

    2015-01-01

    This paper presents a study that explores how newly qualified registered nurses experience their leadership role in the ward-based nursing care team. A nurse's clinical leadership affects the quality of care provided. Newly qualified nurses experience difficulties during the transition period from student to qualified professional and find it challenging to lead nursing care. Twelve nurses were interviewed and the transcribed texts analysed using qualitative content analysis to assess both manifest and latent content. Five themes were identified: feeling stranded; forming well-functioning teams; learning to lead; having the courage, strength, and desire to lead; and ensuring appropriate care. The findings indicate that many factors limit nurses' leadership but some circumstances are supportive. The leadership prerequisites for newly registered nurses need to improve, emphasizing different ways to create a supportive atmosphere that promotes professional development and job satisfaction. To increase nurse retention and promote quality of care, nurse managers need to clarify expectations and guide and support newly qualified nurses in a planned way. © 2013 John Wiley & Sons Ltd.

  9. Newly introduced sample preparation techniques: towards miniaturization.

    Science.gov (United States)

    Costa, Rosaria

    2014-01-01

    Sampling and sample preparation are of crucial importance in an analytical procedure, representing quite often a source of errors. The technique chosen for the isolation of analytes greatly affects the success of a chemical determination. On the other hand, growing concerns about environmental and human safety, along with the introduction of international regulations for quality control, have moved the interest of scientists towards specific needs. Newly introduced sample preparation techniques are challenged to meet new criteria: (i) miniaturization, (ii) higher sensitivity and selectivity, and (iii) automation. In this survey, the most recent techniques introduced in the field of sample preparation will be described and discussed, along with many examples of applications.

  10. Modeling of Karachaganak field development

    Science.gov (United States)

    Sadvakasov, A. A.; Shamsutdinova, G. F.; Almukhametova, E. M.; Gabdrakhmanov, N. Kh

    2018-05-01

    Management of a geological deposit includes the study and analysis of oil recovery, identification of factors influencing production performance and oil-bearing rock flooding, reserve recovery and other indicators characterizing field development in general. Regulation of oil deposits exploitation is a mere control over the fluid flow within a reservoir, which is ensured through the designed system of development via continuous improvement of production and injection wells placement, optimum performance modes, service conditions of downhole and surface oil-field equipment taking into account various changes and physical-geological properties of a field when using modern equipment to obtain the best performance indicators.

  11. Development of ODL in a Newly Industrialized Country according to Face-to-Face Contact, ICT, and E-Readiness

    Directory of Open Access Journals (Sweden)

    J. Marinda van Zyl

    2013-03-01

    Full Text Available A large number of unqualified and under-qualified in-service teachers are holding back socio-economical development in South Africa, a newly industrialized country. Open and distance learning (ODL provides an innovative strategy and praxis for developing and newly industrialized countries to reach their educational and socio-economical objectives through professional development and training. In order to examine factors which affect the success of ODL offered by the North-West University in South Africa, a qualitative and quantitative research approach is used. Factors examined include face-to-face classroom contact, the implementation and use of ICTs, and e-readiness. The relationships between these factors are also discussed. A questionnaire was administered to 87 teacher-students in four Advanced Certificate in Education (ACE programs to collect quantitative data regarding aspects of their classes and the e-readiness of students. This data was qualitatively elaborated upon by three semi-structured, open-ended focus-group interviews. Besides descriptive statistics, Spearman’s rank-order correlations (r were determined between variables pertaining to negative feelings towards face-to-face classroom contact, ODL as students’ choice of delivery mode, and students’ positive attitude towards information and communication technology (ICT. Combined quantitative and qualitative findings were used to evaluate the effectiveness of contact classes as well as the e-readiness of students towards the attainment of ODL development Phase D. This phase refers to UNESCO’s description of ICT implementation, integration, and use. Relationships (Spearman’s rank-order correlations between ODL, as teacher-students’ choice of educational delivery mode, and aspects of their e-readiness suggest that the e-readiness of teacher-students is implicit to their choice of ODL as educational delivery mode for professional development.

  12. Erosion of newly developed CFCs and Be under disruption heat loads

    Science.gov (United States)

    Nakamura, K.; Akiba, M.; Araki, M.; Dairaku, M.; Sato, K.; Suzuki, S.; Yokoyama, K.; Linke, J.; Duwe, R.; Bolt, H.; Roedig, M.

    1996-10-01

    An evaluation of the erosion under disruption heat loads is very important to the lifetime prediction of divertor armour tiles of next fusion devices such as ITER. In particular, erosion data on CFCs (carbon fiber reinforced composites) and beryllium (Be) as the armour materials is urgently required in the ITER design. For CFCs, high heat flux experiments on the newly developed CFCs with high thermal conductivity have been performed under the heat flux of around 800-2000 MW/m 2 and the pulse length of 2-5 ms in JAERI electron beam irradiation systems (JEBIS). As a result, the weight losses of B 4C doped CFCs after heating were almost same to those of the non doped CFC up to 5 wt% boron content. For Be, we have carried out our first disruption experiments on S65/C grade Be specimens in the Juelich divertor test facility in hot cells (JUDITH) facility as a frame work of the J—EU collaboration. The heating conditions were heat loads of 1250-5000 MW/m 2 for 2-8 ms, and the heated area was 3 × 3 mm 2. As a result, the protuberances of the heated area of Be were observed under the lower heat flux.

  13. Erosion of newly developed CFCs and Be under disruption heat loads

    International Nuclear Information System (INIS)

    Nakamura, K.; Duwe, R.; Bolt, H.; Roedig, M.

    1996-01-01

    An evaluation of the erosion under disruption heat loads is very important to the lifetime prediction of divertor armour tiles of next fusion devices such as ITER. In particular, erosion data on CFCs (carbon fiber reinforced composites) and beryllium (Be) as the armour materials is urgently required in the ITER design. For CFCs, high heat flux experiments on the newly developed CFCs with high thermal conductivity have been performed under the heat flux of around 800-2000 MW/m 2 and the pulse length of 2-5 ms in JAERI electron beam irradiation systems (JEBIS). As a result, the weight losses of B 4 C doped CFCs after heating were almost same to those of the non doped CFC up to 5 wt% boron content. For Be, we have carried out our first disruption experiments on S65/C grade Be specimens in the Juelich divertor test facility in hot cells (JUDITH) facility as a frame work of the J-EU collaboration. The heating conditions were heat loads of 1250-5000 MW/m 2 for 2-8 ms, and the heated area was 3 x 3 mm 2 . As a result, the protuberances of the heated area of Be were observed under the lower heat flux. (orig.)

  14. Weldability aspects of a newly developed duplex stainless steel LDX 2101

    Energy Technology Data Exchange (ETDEWEB)

    Westin, E.M. [Avesta Research Centre, Avesta (Sweden). Outokumpu Stainless; Brolund, B. [SSAB Tunnplat, Borlaenge (Sweden); Hertzman, S. [Outokumpu Stainless Research Foundation, Stockholm (Sweden)

    2008-06-15

    Duplex grades have, due to balanced chemical compositions of both filler and base metals, a weldability that allows for successful welding using a majority of the technically relevant techniques of today. In order to fulfil the performance requirements several aspects must be considered. In the heat affected zone (HAZ) the austenite reformation must be reasonably high and in the weld metal the microstructure must be stable so that e.g. high productivity welding and multi-pass welding are possible, without precipitation of detrimental phases in previous passes. This paper addresses the effect of alloying elements and thermal cycles on phase balance in the high temperature HAZ (HTHAZ) of the newly developed lean duplex grade LDX 2101 (EN 1.4162, UNS S32101). Bead-on-plate welds and simulated weld structures have been produced and investigated using metallography, scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The results are analysed using the thermodynamic database Thermo-Calc and a model for phase transformation based on a paraequilibrium assumption for ferrite-austenite transformation. In the temperature region outside the paraequilibrium domain, growth controlled by diffusion of substitutional elements was considered. The analysis follows a model by Cahn regarding grain boundary nucleated growth and the Hillert-Engberg model on kinetics of spherical and planar growth. (orig.)

  15. NUMERICAL MODELLING OF THE SOIL BEHAVIOUR BY USING NEWLY DEVELOPED ADVANCED MATERIAL MODEL

    Directory of Open Access Journals (Sweden)

    Jan Veselý

    2017-02-01

    Full Text Available This paper describes a theoretical background, implementation and validation of the newly developed Jardine plastic hardening-softening model (JPHS model, which can be used for numerical modelling of the soils behaviour. Although the JPHS model is based on the elasto-plastic theory, like the Mohr-Coulomb model that is widely used in geotechnics, it contains some improvements, which removes the main disadvantages of the MC model. The presented model is coupled with an isotopically hardening and softening law, non-linear elastic stress-strain law, non-associated elasto-plastic material description and a cap yield surface. The validation of the model is done by comparing the numerical results with real measured data from the laboratory tests and by testing of the model on the real project of the tunnel excavation. The 3D numerical analysis is performed and the comparison between the JPHS, Mohr-Coulomb, Modified Cam-Clay, Hardening small strain model and monitoring in-situ data is done.

  16. Oil and gas field development: an NOC perspective

    Energy Technology Data Exchange (ETDEWEB)

    Kronman, George [Halliburton Energy Services (United States). Landmark Division

    2004-07-01

    Every day, oil companies around the world face real-life field development and management problems like the ones described above. Making timely and well-informed field development decisions are among the most important decisions the management of any oil company can make. The field development phase of the oil and gas life cycle extends from the discovery of a hydrocarbon deposit through initial production. It also includes revitalization of mature and marginal fields. Field development projects require the greatest level of cross-disciplinary integration and the largest investment decisions in the entire oil field life cycle. The ultimate economic success or failure of most fields is set by the quality of decisions made during field development. Oil companies take many different approaches to field development based on unique business drivers, their asset portfolio mix and risk tolerance, access to data and experienced manpower, adoption of technology, availability of capital, ownership, management style and so on. This paper focuses on understanding and addressing the particular field development challenges facing NOCs today. (author)

  17. Parsing multiple processes of high temperature impacts on corn/soybean yield using a newly developed CLM-APSIM modeling framework

    Science.gov (United States)

    Peng, B.; Guan, K.; Chen, M.

    2016-12-01

    Future agricultural production faces a grand challenge of higher temperature under climate change. There are multiple physiological or metabolic processes of how high temperature affects crop yield. Specifically, we consider the following major processes: (1) direct temperature effects on photosynthesis and respiration; (2) speed-up growth rate and the shortening of growing season; (3) heat stress during reproductive stage (flowering and grain-filling); (4) high-temperature induced increase of atmospheric water demands. In this work, we use a newly developed modeling framework (CLM-APSIM) to simulate the corn and soybean growth and explicitly parse the above four processes. By combining the strength of CLM in modeling surface biophysical (e.g., hydrology and energy balance) and biogeochemical (e.g., photosynthesis and carbon-nitrogen interactions), as well as that of APSIM in modeling crop phenology and reproductive stress, the newly developed CLM-APSIM modeling framework enables us to diagnose the impacts of high temperature stress through different processes at various crop phenology stages. Ground measurements from the advanced SoyFACE facility at University of Illinois is used here to calibrate, validate, and improve the CLM-APSIM modeling framework at the site level. We finally use the CLM-APSIM modeling framework to project crop yield for the whole US Corn Belt under different climate scenarios.

  18. Use of newly developed standardized form for interpretation of high-resolution CT in screening for pneumoconiosis

    International Nuclear Information System (INIS)

    Julien, P.J.; Sider, L.; Silverman, J.M.; Dahlgren, J.; Harber, P.; Bunn, W.

    1991-01-01

    This paper reports that although the International Labour Office (ILO) standard for interpretation of the posteroanterior chest radiograph has been available for 10 years, there has been no attempt to standardize the high-resolution CT (HRTC) readings for screening of pneumoconiosis. An integrated respirator surveillance program for 87 workers exposed to inorganic dust was conducted. This program consisted of a detailed occupational exposure history, physical symptoms and signs, spirometry, chest radiography, and HRCT. Two groups of workers with known exposure were studied with HRCT. Group 1 had normal spirometry results and chest radiographs, and group 2 had abnormalities at spirometry or on chest radiographs. The HRCT scans were read independently of the clinical findings and chest radiographs. The HRCT scans were interpreted by using an ILO-based standard form developed by the authors for this project. With the newly developed HRCT form, individual descriptive abnormality localized severity, and overall rating systems have been developed and compared for inter- and intraobserver consistency

  19. Wide-field fundus autofluorescence corresponds to visual fields in chorioretinitis patients

    Directory of Open Access Journals (Sweden)

    Seidensticker F

    2011-11-01

    Full Text Available Florian Seidensticker1, Aljoscha S Neubauer1, Tamer Wasfy1,2, Carmen Stumpf1, Stephan R Thurau1,*, Anselm Kampik1, Marcus Kernt1,*1Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany; 2Department of Ophthalmology, Tanta University, Tanta, Egypt *Both authors contributed equally to this workBackground and objectives: Detection of peripheral fundus autofluorescence (FAF using conventional scanning laser ophthalmoscopes (SLOs is difficult and requires pupil dilation. Here we evaluated the diagnostic properties of wide-field FAF detected by a two-laser wavelength wide-field SLO in uveitis patients.Study design/materials and methods: Observational case series of four patients suffering from different types of posterior uveitis/chorioretinitis. Wide-field FAF images were compared to visual fields. Panretinal FAF was detected by a newly developed SLO, which allows FAF imaging of up to 200° of the retina in one scan without the need for pupil dilation. Visual fields were obtained by Goldmann manual perimetry.Results: Findings from wide-field FAF imaging showed correspondence to visual field defects in all cases.Conclusion: Wide-field FAF allowed the detection of visual field defect-related alterations of the retinal pigment epithelium in all four uveitis cases.Keywords: fundus autofluorescence (FAF, Optomap, wide-field scanning laser ophthalmoscopy, imaging, uveitis, visual field

  20. PCTFPeval: a web tool for benchmarking newly developed algorithms for predicting cooperative transcription factor pairs in yeast.

    Science.gov (United States)

    Lai, Fu-Jou; Chang, Hong-Tsun; Wu, Wei-Sheng

    2015-01-01

    Computational identification of cooperative transcription factor (TF) pairs helps understand the combinatorial regulation of gene expression in eukaryotic cells. Many advanced algorithms have been proposed to predict cooperative TF pairs in yeast. However, it is still difficult to conduct a comprehensive and objective performance comparison of different algorithms because of lacking sufficient performance indices and adequate overall performance scores. To solve this problem, in our previous study (published in BMC Systems Biology 2014), we adopted/proposed eight performance indices and designed two overall performance scores to compare the performance of 14 existing algorithms for predicting cooperative TF pairs in yeast. Most importantly, our performance comparison framework can be applied to comprehensively and objectively evaluate the performance of a newly developed algorithm. However, to use our framework, researchers have to put a lot of effort to construct it first. To save researchers time and effort, here we develop a web tool to implement our performance comparison framework, featuring fast data processing, a comprehensive performance comparison and an easy-to-use web interface. The developed tool is called PCTFPeval (Predicted Cooperative TF Pair evaluator), written in PHP and Python programming languages. The friendly web interface allows users to input a list of predicted cooperative TF pairs from their algorithm and select (i) the compared algorithms among the 15 existing algorithms, (ii) the performance indices among the eight existing indices, and (iii) the overall performance scores from two possible choices. The comprehensive performance comparison results are then generated in tens of seconds and shown as both bar charts and tables. The original comparison results of each compared algorithm and each selected performance index can be downloaded as text files for further analyses. Allowing users to select eight existing performance indices and 15

  1. Development of high field superconducting magnet

    International Nuclear Information System (INIS)

    Irie, Fujio; Takeo, Masakatsu.

    1986-01-01

    Recently, in connection with nuclear fusion research, the development of high field superconducting magnets showed rapid progress. The development of high field magnets of 15 T class by the techniques of winding after heat treatment has been continued in various places, as these techniques are suitable to make large magnets. In 1985, Kyushu University attained the record of 15.5 T. However in high field magnets, there are many problems peculiar to them, and the basic research related to those is demanded. In this report, these general problems, the experience of the design and manufacture in Kyushu University and the related problems are described. The superconducting magnet installed in the Superconducting Magnet Research Center of Kyushu University attained the record of 15.5 T for the first time in March, 1985. In superconducting magnets, very difficult problem must be solved since superconductivity, heat and mechanical force are inter related. The problems of the wire materials for high field, the scale of high field magnets, the condition limiting mean current density, and the development of high field magnets in Kyushu University are described. (Kako, I.)

  2. Flagellation of Pseudomonas aeruginosa in newly divided cells

    Science.gov (United States)

    Zhao, Kun; Lee, Calvin; Anda, Jaime; Wong, Gerard

    2015-03-01

    For monotrichous bacteria, Pseudomonas aeruginosa, after cell division, one daughter cell inherits the old flagellum from its mother cell, and the other grows a new flagellum during or after cell division. It had been shown that the new flagellum grows at the distal pole of the dividing cell when the two daughter cells haven't completely separated. However, for those daughter cells who grow new flagella after division, it still remains unknown at which pole the new flagellum will grow. Here, by combining our newly developed bacteria family tree tracking techniques with genetic manipulation method, we showed that for the daughter cell who did not inherit the old flagellum, a new flagellum has about 90% chances to grow at the newly formed pole. We proposed a model for flagellation of P. aeruginosa.

  3. Surface ultrastuctures of the human laryngeal mucosa - observation by an newly developed technique of SEM cinematography

    International Nuclear Information System (INIS)

    Ohyama, M.; Ohno, I.; Fujita, T.; Adachi, K.

    1981-01-01

    With the newly-developed techniques of SEM cinematography, surface ultrastructures of the human normal and pathological laryngeal mucosa were demonstrated. The high specialization of the laryngeal mucosa with its marked regional differences stresses the fact that even the squamous epithelium and nonciliated epithelium may play a role of utmost importance. All specimens were obtained after laryngectomy from 10 patients affected by laryngeal cancer which had been treated with or without preoperative irradiation of Lineac in total doses of 3,500-4,500 rad. Special attention was paid to the occurrence of microvilli and microplicae in the normal and pathological mucosa of the larynx, and their morphological and physiological significances were discussed briefly. (Auth.)

  4. Transferability of Newly Developed Pear SSR Markers to Other Rosaceae Species.

    Science.gov (United States)

    Fan, L; Zhang, M-Y; Liu, Q-Z; Li, L-T; Song, Y; Wang, L-F; Zhang, S-L; Wu, J

    2013-01-01

    A set of 120 simple sequence repeats (SSRs) was developed from the newly assembled pear sequence and evaluated for polymorphisms in seven genotypes of pear from different genetic backgrounds. Of these, 67 (55.8 %) primer pairs produced polymorphic amplifications. Together, the 67 SSRs detected 277 alleles with an average of 4.13 per locus. Sequencing of the amplification products from randomly picked loci NAUPy31a and NAUpy53a verified the presence of the SSR loci. When the 67 primer pairs were tested on 96 individual members of eight species in the Rosaceae family, 61.2 % (41/67) of the tested SSRs successfully amplified a PCR product in at least one of the Rosaceae genera. The transferability from pear to different species varied from 58.2 % (apple) to 11.9 % (cherry). The ratio of transferability also reflected the closer relationships within Maloideae over Prunoideae. Two pear SSR markers, NAUpy43c and NAUpy55k, could distinguish the 20 different apple genotypes thoroughly, and UPGMA cluster analysis grouped them into three groups at the similarity level of 0.56. The high level of polymorphism and good transferability of pear SSRs to Rosaceae species indicate their promise for application to future molecular screening, map construction, and comparative genomic studies among pears and other Rosaceae species.

  5. Magnetic field dosimeter development

    International Nuclear Information System (INIS)

    Lemon, D.K.; Skorpik, J.R.; Eick, J.L.

    1980-09-01

    In recent years there has been increased concern over potential health hazards related to exposure of personnel to magnetic fields. If exposure standards are to be established, then a means for measuring magnetic field dose must be available. To meet this need, the Department of Energy has funded development of prototype dosimeters at the Battelle Pacific Northwest Laboratory. This manual reviews the principle of operation of the dosimeter and also contains step-by-step instructions for its operation

  6. Cross-Linking Mast Cell Specific Gangliosides Stimulates the Release of Newly Formed Lipid Mediators and Newly Synthesized Cytokines

    Directory of Open Access Journals (Sweden)

    Edismauro Garcia Freitas Filho

    2016-01-01

    Full Text Available Mast cells are immunoregulatory cells that participate in inflammatory processes. Cross-linking mast cell specific GD1b derived gangliosides by mAbAA4 results in partial activation of mast cells without the release of preformed mediators. The present study examines the release of newly formed and newly synthesized mediators following ganglioside cross-linking. Cross-linking the gangliosides with mAbAA4 released the newly formed lipid mediators, prostaglandins D2 and E2, without release of leukotrienes B4 and C4. The effect of cross-linking these gangliosides on the activation of enzymes in the arachidonate cascade was then investigated. Ganglioside cross-linking resulted in phosphorylation of cytosolic phospholipase A2 and increased expression of cyclooxygenase-2. Translocation of 5-lipoxygenase from the cytosol to the nucleus was not induced by ganglioside cross-linking. Cross-linking of GD1b derived gangliosides also resulted in the release of the newly synthesized mediators, interleukin-4, interleukin-6, and TNF-α. The effect of cross-linking the gangliosides on the MAP kinase pathway was then investigated. Cross-linking the gangliosides induced the phosphorylation of ERK1/2, JNK1/2, and p38 as well as activating both NFκB and NFAT in a Syk-dependent manner. Therefore, cross-linking the mast cell specific GD1b derived gangliosides results in the activation of signaling pathways that culminate with the release of newly formed and newly synthesized mediators.

  7. Development and testing of a mobile application to support diabetes self-management for people with newly diagnosed type 2 diabetes: a design thinking case study.

    Science.gov (United States)

    Petersen, Mira; Hempler, Nana F

    2017-06-26

    Numerous mobile applications have been developed to support diabetes-self-management. However, the majority of these applications lack a theoretical foundation and the involvement of people with diabetes during development. The aim of this study was to develop and test a mobile application (app) supporting diabetes self-management among people with newly diagnosed type 2 diabetes using design thinking. The app was developed and tested in 2015 using a design-based research approach involving target users (individuals newly diagnosed with type 2 diabetes), research scientists, healthcare professionals, designers, and app developers. The research approach comprised three major phases: inspiration, ideation, and implementation. The first phase included observations of diabetes education and 12 in-depth interviews with users regarding challenges and needs related to living with diabetes. The ideation phrase consisted of four interactive workshops with users focusing on app needs, in which ideas were developed and prioritized. Finally, 14 users tested the app over 4 weeks; they were interviewed about usability and perceptions about the app as a support tool. A multifunctional app was useful for people with newly diagnosed type 2 diabetes. The final app comprised five major functions: overview of diabetes activities after diagnosis, recording of health data, reflection games and goal setting, knowledge games and recording of psychological data such as sleep, fatigue, and well-being. Users found the app to be a valuable tool for support, particularly for raising their awareness about their psychological health and for informing and guiding them through the healthcare system after diagnosis. The design thinking processes used in the development and implementation of the mobile health app were crucial to creating value for users. More attention should be paid to the training of professionals who introduce health apps. Danish Data Protection Agency: 2012-58-0004. Registered 6

  8. Newly Homeless Youth Typically Return Home

    OpenAIRE

    Milburn, Norweeta G.; Rosenthal, Doreen; Rotheram-Borus, Mary Jane; Mallett, Shelley; Batterham, Philip; Rice, Eric; Solorio, Rosa

    2007-01-01

    165 newly homeless adolescents from Melbourne, Australia and 261 from Los Angeles, United States were surveyed and followed for two years. Most newly homeless adolescents returned home (70% U.S., 47% Australia) for significant amounts of time (39% U.S., 17% Australia more than 12 months) within two years of becoming homeless.

  9. Technetium-99m carboxymethylcellulose: A newly developed fibre marker for gastric emptying studies

    International Nuclear Information System (INIS)

    Schade, J.H.; Hoving, J.; Brouweres, J.R.B.J.; Riedstra-van Gent, H.G.; Zijlstra, J.; Dijkstra, J.P.H.

    1991-01-01

    We report a study of technetium-99m-labelled carboxymethyl-cellulose ( 99m Tc-CMC) as a newly developed non-digestible marker of the solid phase of gastric contents. The radiosynthesis is simple and shows a high labelling efficiency. In vitro and in vivo experiments demonstrated stability of the marker in the gastrointestinal tract during the process of gastric emptying. The gastric half-emptying time in ten healthy volunteers of both sexes was 105±17 min (mean±SD). This rate of gastric emptying is similar to that of non-digestible solid-phase markers such as in vivo labelled 99m Tc-chicken liver or radio-iodinated cellulose. In comparison with digestible solid-phase markers such as 99m Tc-labelled pancake or 99m Tc-cooked egg, gastric emptying of 99m Tc-CMC occurred more slowly, confirming the expected behaviour of a non-digestible solid-phase marker. We conclude that 99m Tc-CMC has the advantage of a simple and rapid labelling procedure and may be useful for clinical studies of gastric emptying. (orig.)

  10. First results from the in-situ temperature measurements by the newly developed downhole tool during the drilling cruise in the hydrothermal fields of the mid-Okinawa Trough

    Science.gov (United States)

    Kitada, K.; Wu, H. Y.; Miyazaki, J.; Akiyama, K.; Nozaki, T.; Ishibashi, J. I.; Kumagai, H.; Maeda, L.

    2016-12-01

    The Okinawa trough is an active backarc basin behind the Ryukyu subduction zone and exhibits active rifting associated with extension of the continental margin. The temperature measurement in this area is essential for understanding hydrothermal system and hydraulic structure. During the CK16-01 cruise this March, we have conducted the in-situ temperature measurements by the newly developed downhole tool, TRDT (Thermo-Resistant Downhole Thermometer) in hydrothermal fields of the mid-Okinawa Trough. The purpose of this measurement is to investigate the in-situ temperature structure in deep-hot zones and its variation after coring and/or drilling. TRDT was designed by JAMSTEC as a memory downhole tool to measure in-situ borehole temperature under the extreme high temperature environment. First trial was conducted in the CK14-04 cruise by the free fall deployment to reduce the operation time. However, there was no temperature data recorded due to the strong vibration during the operation. After CK14-04 cruise, TRDT was modified to improve the function against vibration and shock. The improved TRDT passed the high temperature, vibration and shock tests to ensure the data acquisition of borehole logging. During the CK16-01 cruise, we have first successfully collected the in-situ temperature data from hydrothermal borehole in the Iheya North Knoll with wireline system. The temperature at depth of 187mbsf continued to increase almost linearly from 220 to 245°C during the 20 minute measurements time. This suggests that the inside borehole was cooled down by pumping seawater through drill pipes during the coring and lowering down the TRDT tool to the bottom hole. The in-situ temperature were extrapolated with exponential curve using nonlinear least squares fitting and the estimated equilibrium temperature was 278°C. To recover the in-situ temperature more precisely, the measurement time should kept as long as possible by considering the temperature rating. The operational

  11. Laboratory model study of newly deposited dredger fills using improved multiple-vacuum preloading technique

    Directory of Open Access Journals (Sweden)

    Jingjin Liu

    2017-10-01

    Full Text Available Problems continue to be encountered concerning the traditional vacuum preloading method in field during the treatment of newly deposited dredger fills. In this paper, an improved multiple-vacuum preloading method was developed to consolidate newly dredger fills that are hydraulically placed in seawater for land reclamation in Lingang Industrial Zone of Tianjin City, China. With this multiple-vacuum preloading method, the newly deposited dredger fills could be treated effectively by adopting a novel moisture separator and a rapid improvement technique without sand cushion. A series of model tests was conducted in the laboratory for comparing the results from the multiple-vacuum preloading method and the traditional one. Ten piezometers and settlement plates were installed to measure the variations in excess pore water pressures and moisture content, and vane shear strength was measured at different positions. The testing results indicate that water discharge–time curves obtained by the traditional vacuum preloading method can be divided into three phases: rapid growth phase, slow growth phase, and steady phase. According to the process of fluid flow concentrated along tiny ripples and building of larger channels inside soils during the whole vacuum loading process, the fluctuations of pore water pressure during each loading step are divided into three phases: steady phase, rapid dissipation phase, and slow dissipation phase. An optimal loading pattern which could have a best treatment effect was proposed for calculating the water discharge and pore water pressure of soil using the improved multiple-vacuum preloading method. For the newly deposited dredger fills at Lingang Industrial Zone of Tianjin City, the best loading step was 20 kPa and the loading of 40–50 kPa produced the highest drainage consolidation. The measured moisture content and vane shear strength were discussed in terms of the effect of reinforcement, both of which indicate

  12. THE NEXUS BETWEEN ENERGY CONSUMPTION AND FINANCIAL DEVELOPMENT WITH ASYMMETRIC CAUSALITY TEST: NEW EVIDENCE FROM NEWLY INDUSTRIALIZED COUNTRIES

    Directory of Open Access Journals (Sweden)

    Feyyaz Zeren

    2014-01-01

    Full Text Available In this study, the relationship between energy consumption and financial development is investigated via Hatemi-J asymmetric causality test (2012 which is able to separate positive and negative shocks in analysis. In order to determine different dimensions of financial system, deposit money bank assets to GDP (dbagdp, financial system deposits to GDP (fdgdp and private credit to GDP (pcrdbgdp were used as three different indicators. As a result of this study on Newly Industrialized 7 Countries spanning the period 1971 till 2010, both positive and negative shocks existed for Malaysia and Mexico, causality from energy consumption to financial developments emerged for Philippines in only negative shocks. While two-way causality occurred for India, Turkey and Thailand, there was not for South Africa.

  13. Compact and Light-Weight Solar Spaceflight Instrument Designs Utilizing Newly Developed Miniature Free-Standing Zone Plates: EUV Radiometer and Limb-Scanning Monochromator

    Science.gov (United States)

    Seely, J. F.; McMullin, D. R.; Bremer, J.; Chang, C.; Sakdinawat, A.; Jones, A. R.; Vest, R.

    2014-12-01

    Two solar instrument designs are presented that utilize newly developed miniature free-standing zone plates having interconnected Au opaque bars and no support membrane resulting in excellent long-term stability in space. Both instruments are based on a zone plate having 4 mm outer diameter and 1 to 2 degree field of view. The zone plate collects EUV radiation and focuses a narrow bandpass through a pinhole aperture and onto a silicon photodiode detector. As a miniature radiometer, EUV irradiance is accurately determined from the zone plate efficiency and the photodiode responsivity that are calibrated at the NIST SURF synchrotron facility. The EUV radiometer is pointed to the Sun and measures the absolute solar EUV irradiance in high time cadence suitable for solar physics and space weather applications. As a limb-scanning instrument in low earth orbit, a miniature zone-plate monochromator measures the extinction of solar EUV radiation by scattering through the upper atmosphere which is a measure of the variability of the ionosphere. Both instruments are compact and light-weight and are attractive for CubeSats and other missions where resources are extremely limited.

  14. Duplex ultrasound: Indications and findings in a newly created ...

    African Journals Online (AJOL)

    Duplex ultrasound: Indications and findings in a newly created facility at the University of Calabar Teaching Hospital, Calabar. ... It is recommended that timely referrals be made, and mobile Doppler units be acquired to save more lives and limbs in the developing world. Keywords: Calabar, deep venous thrombosis, duplex ...

  15. Competence of newly qualified registered nurses from a nursing college

    Directory of Open Access Journals (Sweden)

    BG Morolong

    2005-09-01

    Full Text Available The South African education and training system, through its policy of outcomesbased education and training, has made competency a national priority. In compliance to this national requirement of producing competent learners, the South African Nursing Council ( 1999 B require that the beginner professional nurse practitioners and midwives have the necessary knowledge, skills, attitudes and values which will enable them to render efficient professional service. The health care system also demands competent nurse practitioners to ensure quality in health care. In the light of competency being a national priority and a statutory demand, the research question that emerges is, how competent are the newly qualified registered nurses from a specific nursing college in clinical nursing education? A quantitative, non-experimental contextual design was used to evaluate the competence of newly qualified registered nurses from a specific nursing college. The study was conducted in two phases. The first phase dealt with the development of an instrument together with its manual through the conceptualisation process. The second phase focused on the evaluation of the competency of newly qualified nurses using the instrument based on the steps of the nursing process. A pilot study was conducted to test the feasibility of the items of the instrument. During the evaluation phase, a sample of twenty-six newly qualified nurses was selected by simple random sampling from a target population of thirty-six newly qualified registered nurses. However, six participants withdrew from the study. Data was collected in two general hospitals where the newly qualified registered nurses were working. Observation and questioning were used as data collection techniques in accordance with the developed instrument. Measures were taken to ensure internal validity and reliability of the results. To protect the rights of the participants, the researcher adhered to DENOSA’S (1998

  16. A newly developed grab sampling system for collecting stratospheric air over Antarctica

    Directory of Open Access Journals (Sweden)

    Hideyuki Honda

    1996-07-01

    Full Text Available In order to measure the concentrations of various minor constituents and their isotopic ratios in the stratosphere over Antarctica, a simple grab sampling system was newly developed. The sampling system was designed to be launched by a small number of personnel using a rubber balloon under severe experimental conditions. Special attention was paid to minimize the contamination of sample air, as well as to allow easy handling of the system. The sampler consisted mainly of a 15l sample container with electromagnetic and manual valves, control electronics for executing the air sampling procedures and sending the position and status information of the sampler to the ground station, batteries and a transmitter. All these parts were assembled in an aluminum frame gondola with a shock absorbing system for landing. The sampler was equipped with a turn-over mechanism of the gondola to minimize contamination from the gondola, as well as with a GPS receiver and a rawinsonde for its tracking. Total weight of the sampler was about 11kg. To receive, display and store the position and status data of the sampling system at the ground station, a simple data acquisition system with a portable receiver and a microcomputer was also developed. A new gas handling system was prepared to simplify the injection of He gas into the balloon. For air sampling experiments, three sampling systems were launched at Syowa Station (69°00′S, 39°35′E, Antarctica and then recovered on sea ice near the station on January 22 and 25,1996.

  17. Evaluation of newly developed veterinary portable blood glucose meter with hematocrit correction in dogs and cats.

    Science.gov (United States)

    Mori, Akihiro; Oda, Hitomi; Onozawa, Eri; Shono, Saori; Sako, Toshinori

    2017-10-07

    This study evaluated the accuracy of a newly developed veterinary portable blood glucose meter (PBGM) with hematocrit correction in dogs and cats. Sixty-one dogs and 31 cats were used for the current study. Blood samples were obtained from each dog and cat one to six times. Acceptable results were obtained in error grid analysis between PBGM and reference method values (glucose oxidation methods) in both dogs and cats. Bland-Altman plot analysis revealed a mean difference between the PBGM value and reference method value of -1.975 mg/dl (bias) in dogs and 1.339 mg/dl (bias) in cats. Hematocrit values did not affect the results of the veterinary PBGM. Therefore, this veterinary PBGM is clinically useful in dogs and cats.

  18. Newly-graduated midwives transcending barriers: a grounded theory study.

    Science.gov (United States)

    Barry, Michele J; Hauck, Yvonne L; O'Donoghue, Thomas; Clarke, Simon

    2013-12-01

    Midwifery has developed its own philosophy to formalise its unique identity as a profession. Newly-graduated midwives are taught, and ideally embrace, this philosophy during their education. However, embarking in their career within a predominantly institutionalised and the medically focused health-care model may challenge this application. The research question guiding this study was as follows: 'How do newly graduated midwives deal with applying the philosophy of midwifery in their first six months of practice?' The aim was to generate a grounded theory around this social process. This Western Australian grounded theory study is conceptualised within the social theory of symbolic interactionism. Data were collected by means of in-depth, semi-structured interviews with 11 recent midwifery graduates. Participant and interviewer's journals provided supplementary data. The 'constant comparison' approach was used for data analysis. The substantive theory of transcending barriers was generated. Three stages in transcending barriers were identified: Addressing personal attributes, Understanding the 'bigger picture', and finally, 'Evaluating, planning and acting' to provide woman-centred care. An overview of these three stages provides the focus of this article. The theory of transcending barriers provides a new perspective on how newly-graduated midwives deal with applying the philosophy of midwifery in their first six months of practice. A number of implications for pre and post registration midwifery education and policy development are suggested, as well as recommendations for future research. Copyright © 2013 Elsevier Ltd. All rights reserved.

  19. Orbit Correction for the Newly Developed Polarization-Switching Undulator

    Science.gov (United States)

    Obina, Takashi; Honda, Tohru; Shioya, Tatsuro; Kobayashi, Yukinori; Tsuchiya, Kimichika; Yamamoto, Shigeru

    2007-01-01

    A new scheme of undulator magnet arrangements has been proposed and developed as a polarization-switching radiation source, and its test-stand was installed in the 2.5-GeV Photon Factory storage ring (PF ring) in order to investigate the effects on the beam orbit. The closed orbit distortion (COD) over 200 μm was produced in a vertical direction when we switched the polarization of the radiation from the test-stand. In a horizontal direction, the COD was less than 50μm. The results agreed well with the predictions from the magnetic-field measurement on the bench. In order to suppress the CODs and realize a stable operation of the ring with the polarization-switching, we developed an orbit correction system which consists of an encoder to detect motion of magnets, a pair of beam position monitors (BPMs), signal processing parts, and a pair of steering magnets. We succeeded in suppressing the CODs to the level below 3μm using the system even when we switch the polarization at a maximum frequency of 0.8 Hz.

  20. A newly developed lubricant, chitosan laurate, in the manufacture of acetaminophen tablets.

    Science.gov (United States)

    Bani-Jaber, Ahmad; Kobayashi, Asuka; Yamada, Kyohei; Haj-Ali, Dana; Uchimoto, Takeaki; Iwao, Yasunori; Noguchi, Shuji; Itai, Shigeru

    2015-04-10

    To study the usefulness of chitosan laurate (CS-LA), a newly developed chitosan salt, as a lubricant, lubrication properties such as the pressure transmission ratio and ejection force were determined at different concentrations of CS-LA in tableting. In addition, tablet properties such as the tensile strength, disintegration time, and dissolution behavior, were also determined. When CS-LA was mixed at concentrations of 0.1%-3.0%, the pressure transmission ratio was increased in a concentration-dependent manner, and the value at a CS-LA concentration of 3% was equal to that of magnesium stearate (Mg-St), a widely used lubricant. Additionally, a reduction in the ejection force was observed at a concentration from 1%, proving that CS-LA has good lubrication performance. A prolonged disintegration time and decreased tensile strength, which are known disadvantages of Mg-St, were not observed with CS-LA. Furthermore, with CS-LA, retardation of dissolution of the drug from the tablets was not observed. Conjugation of CS with LA was found to be quite important for both lubricant and tablet properties. In conclusion, CS-LA should be useful as an alternative lubricant to Mg-St. Copyright © 2015 Elsevier B.V. All rights reserved.

  1. Recent developments on field gas extraction and sample preparation methods for radiokrypton dating of groundwater

    Science.gov (United States)

    Yokochi, Reika

    2016-09-01

    Current and foreseen population growths will lead to an increased demand in freshwater, large quantities of which is stored as groundwater. The ventilation age is crucial to the assessment of groundwater resources, complementing the hydrological model approach based on hydrogeological parameters. Ultra-trace radioactive isotopes of Kr (81 Kr and 85 Kr) possess the ideal physical and chemical properties for groundwater dating. The recent advent of atom trap trace analyses (ATTA) has enabled determination of ultra-trace noble gas radioisotope abundances using 5-10 μ L of pure Kr. Anticipated developments will enable ATTA to analyze radiokrypton isotope abundances at high sample throughput, which necessitates simple and efficient sample preparation techniques that are adaptable to various sample chemistries. Recent developments of field gas extraction devices and simple and rapid Kr separation method at the University of Chicago are presented herein. Two field gas extraction devices optimized for different sampling conditions were recently designed and constructed, aiming at operational simplicity and portability. A newly developed Kr purification system enriches Kr by flowing a sample gas through a moderately cooled (138 K) activated charcoal column, followed by a gentle fractionating desorption. This simple process uses a single adsorbent and separates 99% of the bulk atmospheric gases from Kr without significant loss. The subsequent two stages of gas chromatographic separation and a hot Ti sponge getter further purify the Kr-enriched gas. Abundant CH4 necessitates multiple passages through one of the gas chromatographic separation columns. The presented Kr separation system has a demonstrated capability of extracting Kr with > 90% yield and 99% purity within 75 min from 1.2 to 26.8 L STP of atmospheric air with various concentrations of CH4. The apparatuses have successfully been deployed for sampling in the field and purification of groundwater samples.

  2. Immunoparesis in newly diagnosed Multiple Myeloma patients

    DEFF Research Database (Denmark)

    Sorrig, Rasmus; Klausen, Tobias W.; Salomo, Morten

    2017-01-01

    Immunoparesis (hypogammaglobulinemia) is associated to an unfavorable prognosis in newly diagnosed Multiple myeloma (MM) patients. However, this finding has not been validated in an unselected population-based cohort. We analyzed 2558 newly diagnosed MM patients in the Danish Multiple Myeloma...

  3. MUSE integral-field spectroscopy towards the Frontier Fields cluster Abell S1063 I. Data products and redshift identifications

    NARCIS (Netherlands)

    Karman, W.; Caputi, K. I.; Grillo, C.; Balestra, I.; Rosati, P.; Vanzella, E.; Coe, D.; Christensen, L.; Koekemoer, A. M.; Kruehler, T.; Lombardi, M.; Mercurio, A.; Nonino, M.; van der Wel, A.

    We present the first observations of the Frontier Fields cluster Abell S1063 taken with the newly commissioned Multi Unit Spectroscopic Explorer ( MUSE) integral field spectrograph. Because of the relatively large field of view ( 1 arcmin(2)), MUSE is ideal to simultaneously target multiple galaxies

  4. Some stochastic techniques in quantization, new developments in Markov fields and quantum fields

    International Nuclear Information System (INIS)

    Albeverio, S.; Zegarlinski, B.

    1990-01-01

    In these lectures we intend to discuss a few recent developments in the area of interactions between quantum fields and Markow fields in which we have been involved. We stress particularly developments involving techniques of stochastic analysis and where mathematical results have been obtained. In sections 1 and 2 we discuss recent developments in the study and applications of the theory of Dirichlet forms in its relations with quantum mechanics and quantum field theory. In our opinion, this theory provides a natural setting for the study of the singular stochastic processes associated with quantum theory. In section 3 we discuss a recent rigorous construction of a convergent simplicial approximation to quantum fields. We look upon these developments as a first step towards a mathematical realization, at least in 2 space-time dimensions, of a convergent 'Regge-calculus', and as first steps to the mathematical control of more general models (like e.g. models involving actions of Chern-Simons type) in the continuum. In Sect. 4 we discuss applications of some stochastic techniques to the study of gauge fields and Higgs fields, mainly in 2 space time dimensions and certain non linear electromagnetic-type fields in 4-space-time dimensions. (orig./HSI)

  5. A Newly Developed Method for Computing Reliability Measures in a Water Supply Network

    Directory of Open Access Journals (Sweden)

    Jacek Malinowski

    2016-01-01

    Full Text Available A reliability model of a water supply network has beens examined. Its main features are: a topology that can be decomposed by the so-called state factorization into a (relativelysmall number of derivative networks, each having a series-parallel structure (1, binary-state components (either operative or failed with given flow capacities (2, a multi-state character of the whole network and its sub-networks - a network state is defined as the maximal flow between a source (sources and a sink (sinks (3, all capacities (component, network, and sub-network have integer values (4. As the network operates, its state changes due to component failures, repairs, and replacements. A newly developed method of computing the inter-state transition intensities has been presented. It is based on the so-called state factorization and series-parallel aggregation. The analysis of these intensities shows that the failure-repair process of the considered system is an asymptotically homogenous Markov process. It is also demonstrated how certain reliability parameters useful for the network maintenance planning can be determined on the basis of the asymptotic intensities. For better understanding of the presented method, an illustrative example is given. (original abstract

  6. Generational differences among newly licensed registered nurses.

    Science.gov (United States)

    Keepnews, David M; Brewer, Carol S; Kovner, Christine T; Shin, Juh Hyun

    2010-01-01

    Responses of 2369 newly licensed registered nurses from 3 generational cohorts-Baby Boomers, Generation X, and Generation Y-were studied to identify differences in their characteristics, work-related experiences, and attitudes. These responses revealed significant differences among generations in: job satisfaction, organizational commitment, work motivation, work-to-family conflict, family-to-work conflict, distributive justice, promotional opportunities, supervisory support, mentor support, procedural justice, and perceptions of local job opportunities. Health organizations and their leaders need to anticipate intergenerational differences among newly licensed nurses and should provide for supportive working environments that recognize those differences. Orientation and residency programs for newly licensed nurses should be tailored to the varying needs of different generations. Future research should focus on evaluating the effectiveness of orientation and residency programs with regard to different generations so that these programs can be tailored to meet the varying needs of newly licensed nurses at the start of their careers. Copyright 2010 Mosby, Inc. All rights reserved.

  7. Mentorship for newly appointed physicians: a strategy for enhancing patient safety?

    Science.gov (United States)

    Harrison, Reema; McClean, Serwaa; Lawton, Rebecca; Wright, John; Kay, Clive

    2014-09-01

    Mentorship is an increasingly popular innovation from business and industry that is being applied in health-care contexts. This paper explores the concept of mentorship for newly appointed physicians in their first substantive senior post, and specifically its utilization to enhance patient safety. Semi-structured face to face and telephone interviews with Medical Directors (n = 5), Deputy Medical Directors (n = 4), and Clinical Directors (n = 6) from 9 acute NHS Trusts in the Yorkshire and Humber region in the north of England. A focused thematic analysis was used. A number of beneficial outcomes were associated with mentorship for newly appointed physicians including greater personal and professional support, organizational commitment, and general well-being. Providing newly appointed senior physicians with support through mentorship was considered to enhance the safety of patient care. Mentorship may prevent or reduce active failures, be used to identify threats in the local working environment, and in the longer term, address latent threats to safety within the organization by encouraging a healthier safety culture. Offering mentorship to all newly appointed physicians in their first substantive post in health care may be a useful strategy to support the development of their clinical, professional, and personal skills in this transitional period that may also enhance the safety of patient care.

  8. [An Introduction to A Newly-developed "Acupuncture Needle Manipulation Training-evaluation System" Based on Optical Motion Capture Technique].

    Science.gov (United States)

    Zhang, Ao; Yan, Xing-Ke; Liu, An-Guo

    2016-12-25

    In the present paper, the authors introduce a newly-developed "Acupuncture Needle Manipulation Training-evaluation System" based on optical motion capture technique. It is composed of two parts, sensor and software, and overcomes some shortages of mechanical motion capture technique. This device is able to analyze the data of operations of the pressing-hand and needle-insertion hand during acupuncture performance and its software contains personal computer (PC) version, Android version, and Internetwork Operating System (IOS) Apple version. It is competent in recording and analyzing information of any ope-rator's needling manipulations, and is quite helpful for teachers in teaching, training and examining students in clinical practice.

  9. The effect of strain distribution on microstructural developments during forging in a newly developed nickel base superalloy

    Energy Technology Data Exchange (ETDEWEB)

    Buckingham, R.C. [Institute of Structural Materials, Swansea University, Bay Campus, Fabian Way, Swansea SA1 8EN (United Kingdom); Argyrakis, C.; Hardy, M.C. [Rolls-Royce plc, PO Box 31, Derby DE24 8BJ (United Kingdom); Birosca, S., E-mail: 522042@swansea.ac.uk [Institute of Structural Materials, Swansea University, Bay Campus, Fabian Way, Swansea SA1 8EN (United Kingdom)

    2016-01-27

    In the current study, the effect of strain distribution in a simple forging geometry on the propensity for recrystallization, and its impact on mechanical properties has been investigated in a newly developed experimental nickel-based superalloy. The new alloy was produced via a Powder Metallurgy (PM) route and was subsequently Hot Isostatic Processed (HIP), isothermally forged, and heat treated to produce a coarse grain microstructure with average grain size of 23–32 μm. The alloy was examined by means of Electron Back-Scatter Diffraction (EBSD) to characterise the microstructural features such as grain orientation and morphology, grain boundary characteristics and the identification of potential Prior Particle Boundaries (PPBs) throughout each stage of the processing route. Results at the central region of the cross-section plane parallel to the loading direction showed significant microstructural differences across the forging depth. This microstructural variation was found to be highly dependent on the value of local strain imparted during forging such that areas of low effective strain showed partial recrystallisation and a necklace grain structure was observed following heat treatment. Meanwhile, a fully recrystallised microstructure with no PPBs was observed in the areas of high strain values, in the central region of the forging.

  10. Guidelines for developing certification programs for newly generated TRU waste

    International Nuclear Information System (INIS)

    Whitty, W.J.; Ostenak, C.A.; Pillay, K.K.S.; Geoffrion, R.R.

    1983-05-01

    These guidelines were prepared with direction from the US Department of Energy (DOE) Transuranic (TRU) Waste Management Program in support of the DOE effort to certify that newly generated TRU wastes meet the Waste Isolation Pilot Plant (WIPP) Waste Acceptance Criteria. The guidelines provide instructions for generic Certification Program preparation for TRU-waste generators preparing site-specific Certification Programs in response to WIPP requirements. The guidelines address all major aspects of a Certification Program that are necessary to satisfy the WIPP Waste Acceptance Criteria and their associated Compliance Requirements and Certification Quality Assurance Requirements. The details of the major element of a Certification Program, namely, the Certification Plan, are described. The Certification Plan relies on supporting data and control documentation to provide a traceable, auditable account of certification activities. Examples of specific parts of the Certification Plan illustrate the recommended degree of detail. Also, a brief description of generic waste processes related to certification activities is included

  11. Newly democratic Mongolia offering exploration contracts

    International Nuclear Information System (INIS)

    Penttila, W.C.

    1992-01-01

    This paper reports that Mongolia, formerly the Mongolian People's Republic, is working to open its exploration prospects to international operators as it emerges as the world's 15th largest independent nation. The country, about the same size as Alaska with a population of 2 million, held its first free election in July 1990. The newly elected government drafted a constitution that took effect Feb. 12, 1992. The document modifies the previous government's structures to eliminate bureaucracy and allows for political pluralism. At the same time, the government is formulating energy policies, state oil company structure, and resource development philosophy

  12. Comparison of a newly developed binary typing with ribotyping and multilocus sequence typing methods for Clostridium difficile.

    Science.gov (United States)

    Li, Zhirong; Liu, Xiaolei; Zhao, Jianhong; Xu, Kaiyue; Tian, Tiantian; Yang, Jing; Qiang, Cuixin; Shi, Dongyan; Wei, Honglian; Sun, Suju; Cui, Qingqing; Li, Ruxin; Niu, Yanan; Huang, Bixing

    2018-04-01

    Clostridium difficile is the causative pathogen for antibiotic-related nosocomial diarrhea. For epidemiological study and identification of virulent clones, a new binary typing method was developed for C. difficile in this study. The usefulness of this newly developed optimized 10-loci binary typing method was compared with two widely used methods ribotyping and multilocus sequence typing (MLST) in 189 C. difficile samples. The binary typing, ribotyping and MLST typed the samples into 53 binary types (BTs), 26 ribotypes (RTs), and 33 MLST sequence types (STs), respectively. The typing ability of the binary method was better than that of either ribotyping or MLST expressed in Simpson Index (SI) at 0.937, 0.892 and 0.859, respectively. The ease of testing, portability and cost-effectiveness of the new binary typing would make it a useful typing alternative for outbreak investigations within healthcare facilities and epidemiological research. Copyright © 2018 Elsevier B.V. All rights reserved.

  13. Who Is Doing Well? A Typology of Newly Homeless Adolescents

    Science.gov (United States)

    Milburn, Norweeta; Liang, Li-Jung; Lee, Sung-Jae; Rotheram-Borus, Mary Jane; Rosenthal, Doreen; Mallett, Shelley; Lightfoot, Marguerita; Lester, Patricia

    2009-01-01

    There is growing evidence to support developing new typologies for homeless adolescents. Current typologies focus on the risks associated with being homeless, with less consideration of the positive attributes of homeless adolescents. The authors examined both risk and protective factors in a sample of newly homeless adolescents. Using cluster…

  14. Individual consistency in the behaviors of newly-settled reef fish.

    Science.gov (United States)

    White, James R; Meekan, Mark G; McCormick, Mark I

    2015-01-01

    Flexibility in behavior is advantageous for organisms that transition between stages of a complex life history. However, various constraints can set limits on plasticity, giving rise to the existence of personalities that have associated costs and benefits. Here, we document a field and laboratory experiment that examines the consistency of measures of boldness, activity, and aggressive behavior in the young of a tropical reef fish, Pomacentrus amboinensis (Pomacentridae) immediately following their transition between pelagic larval and benthic juvenile habitats. Newly-settled fish were observed in aquaria and in the field on replicated patches of natural habitat cleared of resident fishes. Seven behavioral traits representing aspects of boldness, activity and aggression were monitored directly and via video camera over short (minutes), medium (hours), and long (3 days) time scales. With the exception of aggression, these behaviors were found to be moderately or highly consistent over all time scales in both laboratory and field settings, implying that these fish show stable personalities within various settings. Our study is the first to examine the temporal constancy of behaviors in both field and laboratory settings in over various time scales at a critically important phase during the life cycle of a reef fish.

  15. Newly graduated nurses' empowerment regarding professional competence and other work-related factors.

    Science.gov (United States)

    Kuokkanen, Liisa; Leino-Kilpi, Helena; Numminen, Olivia; Isoaho, Hannu; Flinkman, Mervi; Meretoja, Riitta

    2016-01-01

    Although both nurse empowerment and competence are fundamental concepts of describing newly graduated nurses' professional development and job satisfaction, only few studies exist on the relationship between these concepts. Therefore, the purpose of this study was to determine how newly graduated nurses assess their empowerment and to clarify professional competence compared to other work-related factors. A descriptive, cross-sectional and correlational design was applied. The sample comprised newly graduated nurses (n = 318) in Finland. Empowerment was measured using the 19-item Qualities of an Empowered Nurse scale and the Nurse Competence Scale measured nurses' self-assessed generic competence. In addition to demographic data, the background data included employment sector (public/private), job satisfaction, intent to change/leave job, work schedule (shifts/business hours) and assessments of the quality of care in the workplace. The data were analysed statistically by using Spearman's correlation coefficient as well as the One-Way and Multivariate Analysis of Variance. Cronbach's alpha coefficient was used to estimate the internal consistency. Newly graduated nurses perceived their level of empowerment and competence fairly high. The association between nurse empowerment and professional competence was statistically significant. Other variables correlating positively to empowerment included employment sector, age, job satisfaction, intent to change job, work schedule, and satisfaction with the quality of care in the work unit. The study indicates competence had the strongest effect on newly graduated nurses' empowerment. New graduates need support and career opportunities. In the future, nurses' further education and nurse managers' resources for supporting and empowering nurses should respond to the newly graduated nurses' requisites for attractive and meaningful work.

  16. Adapted to change: The rapid development of symbiosis in newly settled, fast-maturing chemosymbiotic mussels in the deep sea.

    Science.gov (United States)

    Laming, Sven R; Duperron, Sébastien; Gaudron, Sylvie M; Hilário, Ana; Cunha, Marina R

    2015-12-01

    Symbioses between microbiota and marine metazoa occur globally at chemosynthetic habitats facing imminent threat from anthropogenic disturbance, yet little is known concerning the role of symbiosis during early development in chemosymbiotic metazoans: a critical period in any benthic species' lifecycle. The emerging symbiosis of Idas (sensu lato) simpsoni mussels undergoing development is assessed over a post-larval-to-adult size spectrum using histology and fluorescence in situ hybridisation (FISH). Post-larval development shows similarities to that of both heterotrophic and chemosymbiotic mussels. Data from newly settled specimens confirm aposymbiotic, planktotrophic larval development. Sulphur-oxidising (SOX) symbionts subsequently colonise multiple exposed, non-ciliated epithelia shortly after metamorphosis, but only become abundant on gills as these expand with greater host size. This wide-spread bathymodiolin recorded from sulphidic wood, bone and cold-seep habitats, displays a suite of adaptive traits that could buffer against anthropogenic disturbance. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. A new mixed self-consistent field procedure

    Science.gov (United States)

    Alvarez-Ibarra, A.; Köster, A. M.

    2015-10-01

    A new approach for the calculation of three-centre electronic repulsion integrals (ERIs) is developed, implemented and benchmarked in the framework of auxiliary density functional theory (ADFT). The so-called mixed self-consistent field (mixed SCF) divides the computationally costly ERIs in two sets: far-field and near-field. Far-field ERIs are calculated using the newly developed double asymptotic expansion as in the direct SCF scheme. Near-field ERIs are calculated only once prior to the SCF procedure and stored in memory, as in the conventional SCF scheme. Hence the name, mixed SCF. The implementation is particularly powerful when used in parallel architectures, since all RAM available are used for near-field ERI storage. In addition, the efficient distribution algorithm performs minimal intercommunication operations between processors, avoiding a potential bottleneck. One-, two- and three-dimensional systems are used for benchmarking, showing substantial time reduction in the ERI calculation for all of them. A Born-Oppenheimer molecular dynamics calculation for the Na+55 cluster is also shown in order to demonstrate the speed-up for small systems achievable with the mixed SCF. Dedicated to Sourav Pal on the occasion of his 60th birthday.

  18. Newly developed low-temperature scanning tunneling microscope and its application to the study of superconducting materials

    International Nuclear Information System (INIS)

    Gao, F.; Dai, C.; Chen, Z.; Huang, G.; Bai, C.; Tao, H.; Yin, B.; Yang, Q.; Zhao, Z.

    1994-01-01

    A newly developed scanning tunneling microscope (STM) capable of operating at room temperature, 77 K, and 4.2 K is presented. This compact STM has a highly symmetric and rigid tunneling unit designed as an integral frame except the coarse and fine adjustment parts. The tunneling unit is incorporated into a small vacuum chamber that is usually pumped down to 2x10 -4 Pa to avoid water contamination. The fine mechanic adjustment makes the tip approach the sample in 5 nm steps. The coarse adjustment not only changes the distance between the tip and the sample, but also adjusts the tip to be normal to the surface of the sample. With this low-temperature STM atomic resolution images of Bi-2212 single-crystal and large-scale topographies of a YBa 2 Cu 3 O 7 thin film are observed at 77 K

  19. Newly-Developed 3D GRMHD Code and its Application to Jet Formation

    Science.gov (United States)

    Mizuno, Y.; Nishikawa, K.-I.; Koide, S.; Hardee, P.; Fishman, G. J.

    2006-01-01

    We have developed a new three-dimensional general relativistic magnetohydrodynamic code by using a conservative, high-resolution shock-capturing scheme. The numerical fluxes are calculated using the HLL approximate Riemann solver scheme. The flux-interpolated constrained transport scheme is used to maintain a divergence-free magnetic field. We have performed various 1-dimensional test problems in both special and general relativity by using several reconstruction methods and found that the new 3D GRMHD code shows substantial improvements over our previous model. The . preliminary results show the jet formations from a geometrically thin accretion disk near a non-rotating and a rotating black hole. We will discuss the jet properties depended on the rotation of a black hole and the magnetic field strength.

  20. Further Development of HS Field Theory

    Science.gov (United States)

    Abdurrahman, Abdulmajeed; Faridani, Jacqueline; Gassem, Mahmoud

    2006-04-01

    We present a systematic treatment of the HS Field theory of the open bosonic string and discuss its relationship to other full string field theories of the open bosonic string such as Witten's theory and the CVS theory. In the development of the HS field theory we encounter infinite dimensional matrices arising from the change of representation between the two theories, i.e., the HS field theory and the full string field theory. We give a general procedure of how to invert these gigantic matrices. The inversion of these matrices involves the computation of many infinite sums. We give the values of these sums and state their generalizations arising from considering higher order vertices (i.e., more than three strings) in string field theory. Moreover, we give a general procedure, on how to evaluate the generalized sums, that can be extended to many generic sums of similar properties. We also discuss the conformal operator connecting the HS field theory to that of the CVS string field theory.

  1. Feasibility and preliminary effects of an intervention targeting schema development for caregivers of newly admitted hospice patients.

    Science.gov (United States)

    Lindstrom, Kathryn B; Mazurek Melnyk, Bernadette

    2013-06-01

    The transition to hospice care is a stressful experience for caregivers, who report high anxiety, unpreparedness, and lack of confidence. These sequelae are likely explained by the lack of an accurate cognitive schema, not knowing what to expect or how to help their loved one. Few interventions exist for this population and most do not measure preparedness, confidence, and anxiety using a schema building a conceptual framework for a new experience. The purpose of this study was to test the feasibility and preliminary effects of an intervention program, Education and Skill building Intervention for Caregivers of Hospice patients (ESI-CH), using an innovative conceptual design that targets cognitive schema development and basic skill building for caregivers of loved ones newly admitted to hospice services. A pre-experimental one-group pre- and post-test study design was used. Eighteen caregivers caring for loved ones in their homes were recruited and twelve completed the pilot study. Depression, anxiety, activity restriction, preparedness, and beliefs/confidence were measured. Caregivers reported increased preparedness, more helpful beliefs, and more confidence about their ability to care for their loved one. Preliminary trends suggested decreased anxiety levels for the intervention group. Caregivers who completed the intervention program rated the program very good or excellent, thought the information was helpful and timely, and would recommend it to friends. Results show promise that the ESI-CH program may assist as an evidence-based program to support caregivers in their role as a caregiver to a newly admitted hospice patient.

  2. Diagnostic Development on NSTX

    International Nuclear Information System (INIS)

    A.L. Roquemore; D. Johnson; R. Kaita; et al

    1999-01-01

    Diagnostics are described which are currently installed or under active development for the newly commissioned NSTX device. The low aspect ratio (R/a less than or equal to 1.3) and low toroidal field (0.1-0.3T) used in this device dictate adaptations in many standard diagnostic techniques. Technical summaries of each diagnostic are given, and adaptations, where significant, are highlighted

  3. Fluorescent and radiolabelling of pepsin-digested human glomerular basement membrane with a newly developed hydroxy-coumarin derivative (CASE)

    International Nuclear Information System (INIS)

    Rand-Weaver, M.; Abuknesha, R.A.; Price, R.G.

    1985-01-01

    The labelling of pepsin-digested human glomerular basement membrane (pHGBM) with a newly developed fluorescent iodine acceptor 7-hydroxy-coumarin-3-acetic acid N-hydroxysucciniimydyl ester (CASE) is described. The binding of a monoclonal antibody to pHGBM was assessed by radiobinding assays, and when directly iodinated pHGBM was used there was no apparent binding. When CASE was conjugated to pHGBM prior to iodination 11% binding was achieved. CASE acting as an iodine acceptor may be useful for proteins containing few or inaccessible tyrosine residues or which are destroyed by introduction of 125 I. Since CASE is fluorescent, small amounts of material can be detected during isolation prior to iodination. (orig.)

  4. Development of geothermal field following the 2000 eruption of Usu volcano as revealed by ground temperature, resistivity and self-potential variations

    Directory of Open Access Journals (Sweden)

    T. Mogi

    2007-06-01

    Full Text Available The 2000 eruption of Usu volcano, NE Japan, took place on the foot of the somma, and formed a cryptodome of 65 m high accompanying numerous faults. We made repeated measurements of ground temperature, Self-Potential (SP and electrical resistivity, in order to clarify the mechanism of development of the newly formed geothermal field on the fault zone. Prior to the expansion of the geothermal field, we detected a resistive zone at the center of the geothermal zone and it supposed to evidence that the zone involving dry steam phase had been formed beneath the fault zone. A rapid expansion of the geothermal field followed along the fault zone away from the craters. The place of maximum amplitude of the SP field also migrated following the expansion of the high ground temperature zone. The high resistive part has shrunk as a consequence of the progress of condensation to warm the surroundings. Based on the observations, we delineated the process of the hydrothermal circulation. Considering the topographic effect of the SP field observed on the highly permeable zone in the Usu somma, the potential flow along the slope of the soma was expected to play an important role to promote the rapid expansion of the geothermal field and the migration of the most active part.

  5. A compilation of consumers' stories: the development of a video to enhance medication adherence in newly transplanted kidney recipients.

    Science.gov (United States)

    Low, Jac Kee; Crawford, Kimberley; Manias, Elizabeth; Williams, Allison

    2016-04-01

    To describe the design, development and evaluation of a consumer-centred video, which was underpinned by the Theory of Planned Behaviour and it was created to educate newly transplanted kidney recipients about the importance of medication adherence. Kidney transplantation is a treatment whereby medication adherence is critical to ensure long-term kidney graft success. To date, many interventions aimed to improve medication adherence in kidney transplantation have been conducted but consumers remain largely uninvolved in the interventional design. Qualitative sequential design. Twenty-two participants who had maintained their kidney transplant for at least 8 months and three participants who had experienced a kidney graft loss due to non-adherence were interviewed from March-May 2014 in Victoria, Australia. These interviews were independently reviewed by two researchers and were used to guide the design of the story plot and to identify storytellers for the video. The first draft of the video was evaluated by a panel of seven experts in the field, one independent educational expert and two consumers using Lynn's content validity questionnaire. The content of the video was regarded as highly relevant and comprehensive, which achieved a score of >3·7 out of a possible 4. The final 18-minute video comprised 15 sections. Topics included medication management, the factors affecting medication adherence and the absolute necessity of adherence to immunosuppressive medications for graft survival. This paper has demonstrated the feasibility of creating a consumer-driven video that supports medication adherence in an engaging way. © 2015 John Wiley & Sons Ltd.

  6. Microbial control of Agrilus planipennis (Coleoptera: Buprestidae) with Beauveria bassiana strain GHA: field applications

    Science.gov (United States)

    Houping Liu; Leah S. Bauer

    2008-01-01

    The effects of Beauveria bassiana strain GHA, applied as BotaniGard ES, on newly colonised and well-established populations of emerald ash borer, Agrilus planipennis (Coleoptera: Buprestidae) were evaluated in the field using foliar and trunk sprays in Michigan in 2004-2005. Results from field trials at a newly colonised white ash...

  7. SRS environmental technology development field test platform

    International Nuclear Information System (INIS)

    Riha, B.D.; Rossabi, J.; Eddy-Dilek, C.A.

    1995-01-01

    A critical and difficult step in the development and implementation of new technologies for environmental monitoring and characterization is successfully transferring these technologies to industry and government users for routine assessment and compliance activities. The Environmental Sciences Section of the DOE Savannah River Technology Center provides a forum for developers, potential users, and regulatory organizations to evaluate new technologies in comparison with baseline technologies in a well characterized field test bed. The principal objective of this project is to conduct comprehensive, objective field tests of monitoring and characterization technologies that are not currently used in EPA standard methods and evaluate their performance during actual operating conditions against baseline methods. This paper provides an overview of the field test site and a description of some of the technologies demonstrated at the site including their field applications

  8. Critical thinking dispositions among newly graduated nurses

    Science.gov (United States)

    Wangensteen, Sigrid; Johansson, Inger S; Björkström, Monica E; Nordström, Gun

    2010-01-01

    wangensteen s., johansson i.s., björkström m.e. & nordström g. (2010) Critical thinking dispositions among newly graduated nurses. Journal of Advanced Nursing66(10), 2170–2181. Aim The aim of the study was to describe critical thinking dispositions among newly graduated nurses in Norway, and to study whether background data had any impact on critical thinking dispositions. Background Competence in critical thinking is one of the expectations of nursing education. Critical thinkers are described as well-informed, inquisitive, open-minded and orderly in complex matters. Critical thinking competence has thus been designated as an outcome for judging the quality of nursing education programmes and for the development of clinical judgement. The ability to think critically is also described as reducing the research–practice gap and fostering evidence-based nursing. Methods A cross-sectional descriptive study was performed. The data were collected between October 2006 and April 2007 using the California Critical Thinking Disposition Inventory. The response rate was 33% (n= 618). Pearson’s chi-square tests were used to analyse the data. Results Nearly 80% of the respondents reported a positive disposition towards critical thinking. The highest mean score was on the Inquisitiveness subscale and the lowest on the Truth-seeking subscale. A statistically significant higher proportion of nurses with high critical thinking scores were found among those older than 30 years, those with university education prior to nursing education, and those working in community health care. Conclusion Nurse leaders and nurse teachers should encourage and nurture critical thinking among newly graduated nurses and nursing students. The low Truth-seeking scores found may be a result of traditional teaching strategies in nursing education and might indicate a need for more student-active learning models. PMID:20384637

  9. Proposed tokamak poloidal field system development program

    Energy Technology Data Exchange (ETDEWEB)

    Rogers, J.D.; Vogel, H.F.; Warren, R.W.; Weldon, D.M.

    1977-05-01

    A program is proposed to develop poloidal field components for TNS and EPR size tokamak devices and to test these components in realistic circuits. Emphasis is placed upon the development of the most difficult component, the superconducting ohmic-heating coil. Switches must also be developed for testing the coils, and this switching technology is to be extended to meet the requirements for the large scale tokamaks. Test facilities are discussed; power supplies, including a homopolar to drive the coils, are considered; and poloidal field systems studies are proposed.

  10. Planning for the Management and Disposition of Newly Generated TRU Waste from REDC

    International Nuclear Information System (INIS)

    Coffey, D. E.; Forrester, T. W.; Krause, T.

    2002-01-01

    This paper describes the waste characteristics of newly generated transuranic waste from the Radiochemical Engineering and Development Center at the Oak Ridge National Laboratory and the basic certification structure that will be proposed by the University of Tennessee-Battelle and Bechtel Jacobs Company LLC to the Waste Isolation Pilot Plant for this waste stream. The characterization approach uses information derived from the active production operations as acceptable knowledge for the Radiochemical Engineering and Development Center transuranic waste. The characterization approach includes smear data taken from processing and waste staging hot cells, as well as analytical data on product and liquid waste streams going to liquid waste disposal. Bechtel Jacobs Company and University of Tennessee-Battelle are currently developing the elements of a Waste Isolation Pilot Plant-compliant program with a plan to be certified by the Waste Isolation Pilot Plant for shipment of newly generated transuranic waste in the next few years. The current activities include developing interface plans, program documents, and waste stream specific procedures

  11. Field-aligned currents during northward IMF: Morphology and causes

    DEFF Research Database (Denmark)

    Vennerstrøm, Susanne; Moretto, T.; Rastätter, L.

    2005-01-01

    We present the results of a global MHD simulation of solar wind magnetosphere interaction during northward IMF. In particular, we emphasize the effect of the IMF B y component on the reconnection geometry and the mapping along field lines to the polar ionosphere, through field-aligned currents. We...... find that the existence and geometry of the polar cap is closely connected to the IMF B y component. During strictly northward IMF the simulated magnetosphere can remain essentially closed because the solar wind field lines reconnect in both hemispheres, thereby creating newly reconnected closed...... exist both on open and closed field lines and are created by the shear of the newly reconnected field lines against the mantle field as they are convected tailward by the solar wind. When the IMF rotates from northward toward east, the magnetospheric mapping regions of the NBZ currents likewise rotates...

  12. Kashagan oil field development. Kazakhstan

    International Nuclear Information System (INIS)

    Urbaniak, D.; Gerebizza, E.; Wasse, G.; Kochladze, M.

    2007-12-01

    Based on our research and field investigations of the Kashagan oil field development and relevant infrastructure in the Atyrau and Mangistau regions of Kazakhstan (cities and vicinities of Aktau, Atash, Atyrau, Bautino, Bolashak, Karabatan and Koshanai) evidence has been collected that raises serious concerns about environmental, social and health effects of this oil field development - such as sulphur emissions and storage which may pose serious threats for the communities close to the Kashagan oil facilities and for the Caspian Sea environment. Furthermore, since becoming the single Operator of the North Caspian Sea Production Sharing Agreement (PSA), the Agip Kazakhstan North Caspian Operating Company N.V. (Agip KCO) has failed to release all information available on the environmental, health and social impacts of its operations in the Kashagan oil field. As requested by the local communities and required by Constitution of Kazakhstan Republic and Aarhus Convention on Access to Information, Public Participation in Decision-Making and Access to Justice in Environmental Matters ratified by Kazakhstan in 2001, such information must be made available. There is also a growing concern among the civil society that the European Commission through its officials is publicly expressing support to European oil companies' members of the Agip KCO despite their failure to fulfil basic environmental regulations. This continued support contradicts the European Union's fundamental values and frequent statements related to Human Rights and Sustainable Development. Thousands of people have already been relocated in the region because of sulphur emissions and other highly poisonous chemicals such as mercaptans, which are present at very high levels in Northern Caspian oil. Unprotected storage of large quantities of sulphur is also recognised as a major cause of acid rain on a global level. This Report implores Agip KCO to release all available and required information on the

  13. Engineering fluorescent proteins towards ultimate performances: lessons from the newly developed cyan variants

    International Nuclear Information System (INIS)

    Mérola, Fabienne; Erard, Marie; Fredj, Asma; Pasquier, Hélène

    2016-01-01

    New fluorescent proteins (FPs) are constantly discovered from natural sources, and submitted to intensive engineering based on random mutagenesis and directed evolution. However, most of these newly developed FPs fail to achieve all the performances required for their bioimaging applications. The design of highly optimised FP-based reporters, simultaneously displaying appropriate colour, multimeric state, chromophore maturation, brightness, photostability and environmental sensitivity will require a better understanding of the structural and dynamic determinants of FP photophysics. The recent development of cyan fluorescent proteins (CFPs) like mCerulean3, mTurquoise2 and Aquamarine brings a different view on these questions, as in this particular case, a step by step evaluation of critical mutations has been performed within a family of spectrally identical and evolutionary close variants. These efforts have led to CFPs with quantum yields close to unity, near single exponential emission decays, high photostability and complete insensitivity to pH, making them ideal choices as energy transfer donors in FRET and FLIM imaging applications. During this process, it was found that a proper amino-acid choice at only two positions (148 and 65) is sufficient to transform the performances of CFPs: with the help of structural and theoretical investigations, we rationalise here how these two positions critically control the CFP photophysics, in the context of FPs derived from the Aequorea victoria species. Today, these results provide a useful toolbox for upgrading the different CFP donors carried by FRET biosensors. They also trace the route towards the de novo design of FP-based optogenetic devices that will be perfectly tailored to dedicated imaging and sensing applications. (topical review)

  14. Development of field-wide risk based remediation objectives for an aging oil field : Devon Canada Swan Hills Field

    Energy Technology Data Exchange (ETDEWEB)

    Brewster, M.; North, C.; Leighton-Boyce, G. [WorleyParsons Komex, Calgary, AB (Canada); Moore, D. [Devon Canada Corp., Calgary, AB (Canada)

    2006-07-01

    The development of field-wide risk based remediation objectives for the aging Devon Canada Swan Hills oil field was examined along with the key components of the closure strategy. These included source removal to the extent practical, long term monitoring, and achievable risk-based remedial objectives that were appropriate to the remote boreal forest setting of the Swan Hills field. A two stage approach was presented. The first stage involved a field wide background framework which included defining areas of common physical and ecological setting and developing appropriate exposure scenarios. The second stage involved site-specific risk assessments which included adjusting for site-specific conditions and an early demonstration project to prove the concept. A GIS approach was used to identify areas of common physical and ecological setting including: physiography; surface water; land use; vegetation ecozones; surficial and bedrock geology; and water well use. Species lists were compiled for vegetation, terrestrial wildlife (mammals, birds, amphibians), and aquatic species (fish and invertebrates). Major contaminant sources, problem formulation, vegetation bioassays, invertebrate bioassays, black spruce emergence, and guideline development were other topics covered during the presentation. Last, a summary of progress was presented. A field-wide review and development of risk zones and site-specific risk assessment has been completed. A regulatory review is underway. tabs., figs.

  15. Evaluation of the implementation of CRM in developing countries

    OpenAIRE

    Almotairi, Mohammad AT

    2010-01-01

    This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University. Managing relations with customers has been a main concern for business organisations from different sizes and fields. Such a concern has grown rapidly in the last few decades for a number of reasons such as the development of new technologies especially in the field of information technology (IT). Customer Relationship Management (CRM) is a newly emerged concept in the fields of I...

  16. Status of photovoltaics in the Newly Associated States

    International Nuclear Information System (INIS)

    Pietruszko, S.M.; Mikolajuk, A.; Fara, L.; Fara, S.; Vitanov, P.; Stratieva, N.; Rehak, J.; Barinka, R.; Mellikov, E.; Palfy, M.; Shipkovs, P.; Krotkus, A.; Saly, V.; Nemac, F.; Swens, J.; Nowak, S.; Zachariou, A.; Fechner, H.; Passiniemi, P.

    2004-01-01

    The Status of Photovoltaics in the Central and Eastern Europe presents the state of the art of photovoltaics (PV) in the Newly Associated States (NAS): Bulgaria, the Czech Republic, Estonia, Hungary, Latvia, Lithuania, Poland, Romania, Slovakia, Slovenia. The attempt was made to cover all photovoltaics activities in NAS, from research to industry and markets as well as from technology development to dissemination and education. The document covers the following topics and issues: organization of PV research and demonstration activities, stakeholders involved in research and technology development (RTD), scientific potential of NAS PV community, PV activities carried out in NAS countries, PV policies and support mechanisms, achievements and barriers, challenges and needs to the development of PV in the NAS. (authors)

  17. The Activity of Carbohydrate-Degrading Enzymes in the Development of Brood and Newly Emerged workers and Drones of the Carniolan Honeybee, Apis mellifera carnica

    OpenAIRE

    Żółtowska, Krystyna; Lipiński, Zbigniew; Łopieńska-Biernat, Elżbieta; Farjan, Marek; Dmitryjuk, Małgorzata

    2012-01-01

    The activity of glycogen Phosphorylase and carbohydrate hydrolyzing enzymes α-amylase, glucoamylase, trehalase, and sucrase was studied in the development of the Carniolan honey bee, Apis mellifera carnica Pollman (Hymenoptera: Apidae), from newly hatched larva to freshly emerged imago of worker and drone. Phosphorolytic degradation of glycogen was significantly stronger than hydrolytic degradation in all developmental stages. Developmental profiles of hydrolase activity were similar in both ...

  18. Three-dimensional quantification of cardiac surface motion: a newly developed three-dimensional digital motion-capture and reconstruction system for beating heart surgery.

    Science.gov (United States)

    Watanabe, Toshiki; Omata, Sadao; Odamura, Motoki; Okada, Masahumi; Nakamura, Yoshihiko; Yokoyama, Hitoshi

    2006-11-01

    This study aimed to evaluate our newly developed 3-dimensional digital motion-capture and reconstruction system in an animal experiment setting and to characterize quantitatively the three regional cardiac surface motions, in the left anterior descending artery, right coronary artery, and left circumflex artery, before and after stabilization using a stabilizer. Six pigs underwent a full sternotomy. Three tiny metallic markers (diameter 2 mm) coated with a reflective material were attached on three regional cardiac surfaces (left anterior descending, right coronary, and left circumflex coronary artery regions). These markers were captured by two high-speed digital video cameras (955 frames per second) as 2-dimensional coordinates and reconstructed to 3-dimensional data points (about 480 xyz-position data per second) by a newly developed computer program. The remaining motion after stabilization ranged from 0.4 to 1.01 mm at the left anterior descending, 0.91 to 1.52 mm at the right coronary artery, and 0.53 to 1.14 mm at the left circumflex regions. Significant differences before and after stabilization were evaluated in maximum moving velocity (left anterior descending 456.7 +/- 178.7 vs 306.5 +/- 207.4 mm/s; right coronary artery 574.9 +/- 161.7 vs 446.9 +/- 170.7 mm/s; left circumflex 578.7 +/- 226.7 vs 398.9 +/- 192.6 mm/s; P heart surface movement. This helps us better understand the complexity of the heart, its motion, and the need for developing a better stabilizer for beating heart surgery.

  19. Benchmark Modeling of the Near-Field and Far-Field Wave Effects of Wave Energy Arrays

    Energy Technology Data Exchange (ETDEWEB)

    Rhinefrank, Kenneth E; Haller, Merrick C; Ozkan-Haller, H Tuba

    2013-01-26

    This project is an industry-led partnership between Columbia Power Technologies and Oregon State University that will perform benchmark laboratory experiments and numerical modeling of the near-field and far-field impacts of wave scattering from an array of wave energy devices. These benchmark experimental observations will help to fill a gaping hole in our present knowledge of the near-field effects of multiple, floating wave energy converters and are a critical requirement for estimating the potential far-field environmental effects of wave energy arrays. The experiments will be performed at the Hinsdale Wave Research Laboratory (Oregon State University) and will utilize an array of newly developed Buoys' that are realistic, lab-scale floating power converters. The array of Buoys will be subjected to realistic, directional wave forcing (1:33 scale) that will approximate the expected conditions (waves and water depths) to be found off the Central Oregon Coast. Experimental observations will include comprehensive in-situ wave and current measurements as well as a suite of novel optical measurements. These new optical capabilities will include imaging of the 3D wave scattering using a binocular stereo camera system, as well as 3D device motion tracking using a newly acquired LED system. These observing systems will capture the 3D motion history of individual Buoys as well as resolve the 3D scattered wave field; thus resolving the constructive and destructive wave interference patterns produced by the array at high resolution. These data combined with the device motion tracking will provide necessary information for array design in order to balance array performance with the mitigation of far-field impacts. As a benchmark data set, these data will be an important resource for testing of models for wave/buoy interactions, buoy performance, and far-field effects on wave and current patterns due to the presence of arrays. Under the proposed project we will initiate

  20. A model for mentoring newly-appointed nurse educators in nursing education institutions in South Africa.

    Science.gov (United States)

    Seekoe, Eunice

    2014-04-24

    South Africa transformed higher education through the enactment of the Higher Education Act (No. 101 of 1997). The researcher identified the need to develop a model for the mentoring of newly-appointed nurse educators in nursing education institutions in South Africa.  To develop and describe the model for mentoring newly-appointed nurse educators in nursing education institutions in South Africa.  A qualitative and theory-generating design was used (following empirical findings regarding needs analysis) in order to develop the model. The conceptualisation of the framework focused on the context, content, process and the theoretical domains that influenced the model. Ideas from different theories were borrowed from and integrated with the literature and deductive and inductive strategies were applied.  The structure of the model is multidimensional and complex in nature (macro, mesoand micro) based on the philosophy of reflective practice, competency-based practice andcritical learning theories. The assumptions are in relation to stakeholders, context, mentoring, outcome, process and dynamic. The stakeholders are the mentor and mentee within an interactive participatory relationship. The mentoring takes place within the process with a sequence of activities such as relationship building, development, engagement, reflective process and assessment. Capacity building and empowerment are outcomes of mentoring driven by motivation.  The implication for nurse managers is that the model can be used to develop mentoring programmes for newly-appointed nurse educators.

  1. Neutron and photon spectrometry in mixed radiation fields

    International Nuclear Information System (INIS)

    Jancar, A.; Kopecky, Z.; Veskrna, M.

    2014-01-01

    Spectrometric measurements of the mixed fields of neutron and photon radiation in the workplaces with the L-R-0 research reactor located in the UJV Rez and with the Van de Graaff accelerator, located in the UTEF laboratories Prague, are presented in this paper. The experimental spectrometric measurements were performed using a newly developed digital measuring system, based on the technology of analog-digital converters with a very high sampling frequency (up to 2 GHz), in connection with organic scintillation detector, type BC-501A, and stilbene detector. The results of experimental measurements show high quality of spectrometry mixed fields of neutron and photon radiation across the wide dynamic range of measured energy. (authors)

  2. RELATIONSHIP BETWEEN DIFFERENT ALLOGAMIC ASSOCIATED TRAIT CHARACTERISTICS OF THE FIVE NEWLY DEVELOPED CYTOPLASMIC MALE STERILE (CMS LINES IN RICE

    Directory of Open Access Journals (Sweden)

    Nematzadeh GHORBAN ALI

    2006-10-01

    Full Text Available Five suitable maintainer varieties were identifi ed through testcrosses with IR58025A and the transfer of wild abortive cytoplasm was carried out by seven successive backcrosses. Five new CMS lines were developed by this approach in well adapted high yielding improved varietal background such as ‘Nemat’, ‘Neda’, ‘Dasht’, ‘Amol3’ and ‘Champa’. Agronomical characterization and allogamy-associated traits of the fi ve newly developed CMS lines were studied for their interrelationship. Anther length had a signifi cant positive correlation with the duration of glume opening (0.759 and high correlation of (0.698 with the angle between lemma and palea. The results indicated that ‘Nemat’ A, ‘Neda’ A, ‘Dasht’ A are more suitable as parents for hybrid seed production due to their favorable and superior fl oral characteristics in comparison to IR58025A.

  3. Clinical Prediction Model for Time in Therapeutic Range While on Warfarin in Newly Diagnosed Atrial Fibrillation.

    Science.gov (United States)

    Williams, Brent A; Evans, Michael A; Honushefsky, Ashley M; Berger, Peter B

    2017-10-12

    Though warfarin has historically been the primary oral anticoagulant for stroke prevention in newly diagnosed atrial fibrillation (AF), several new direct oral anticoagulants may be preferred when anticoagulation control with warfarin is expected to be poor. This study developed a prediction model for time in therapeutic range (TTR) among newly diagnosed AF patients on newly initiated warfarin as a tool to assist decision making between warfarin and direct oral anticoagulants. This electronic medical record-based, retrospective study included newly diagnosed, nonvalvular AF patients with no recent warfarin exposure receiving primary care services through a large healthcare system in rural Pennsylvania. TTR was estimated as the percentage of time international normalized ratio measurements were between 2.0 and 3.0 during the first year following warfarin initiation. Candidate predictors of TTR were chosen from data elements collected during usual clinical care. A TTR prediction model was developed and temporally validated and its predictive performance was compared with the SAMe-TT 2 R 2 score (sex, age, medical history, treatment, tobacco, race) using R 2 and c-statistics. A total of 7877 newly diagnosed AF patients met study inclusion criteria. Median (interquartile range) TTR within the first year of starting warfarin was 51% (32, 67). Of 85 candidate predictors evaluated, 15 were included in the final validated model with an R 2 of 15.4%. The proposed model showed better predictive performance than the SAMe-TT 2 R 2 score ( R 2 =3.0%). The proposed prediction model may assist decision making on the proper mode of oral anticoagulant among newly diagnosed AF patients. However, predicting TTR on warfarin remains challenging. © 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

  4. The activity of carbohydrate-degrading enzymes in the development of brood and newly emerged workers and drones of the Carniolan honeybee, Apis mellifera carnica.

    Science.gov (United States)

    Żółtowska, Krystyna; Lipiński, Zbigniew; Łopieńska-Biernat, Elżbieta; Farjan, Marek; Dmitryjuk, Małgorzata

    2012-01-01

    The activity of glycogen Phosphorylase and carbohydrate hydrolyzing enzymes α-amylase, glucoamylase, trehalase, and sucrase was studied in the development of the Carniolan honey bee, Apis mellifera carnica Pollman (Hymenoptera: Apidae), from newly hatched larva to freshly emerged imago of worker and drone. Phosphorolytic degradation of glycogen was significantly stronger than hydrolytic degradation in all developmental stages. Developmental profiles of hydrolase activity were similar in both sexes of brood; high activity was found in unsealed larvae, the lowest in prepupae followed by an increase in enzymatic activity. Especially intensive increases in activity occurred in the last stage of pupae and newly emerged imago. Besides α-amylase, the activities of other enzymes were higher in drone than in worker broods. Among drones, activity of glucoamylase was particularly high, ranging from around three times higher in the youngest larvae to 13 times higher in the oldest pupae. This confirms earlier suggestions about higher rates of metabolism in drone broods than in worker broods.

  5. Confidence in leadership among the newly qualified.

    Science.gov (United States)

    Bayliss-Pratt, Lisa; Morley, Mary; Bagley, Liz; Alderson, Steven

    2013-10-23

    The Francis report highlighted the importance of strong leadership from health professionals but it is unclear how prepared those who are newly qualified feel to take on a leadership role. We aimed to assess the confidence of newly qualified health professionals working in the West Midlands in the different competencies of the NHS Leadership Framework. Most respondents felt confident in their abilities to demonstrate personal qualities and work with others, but less so at managing or improving services or setting direction.

  6. Development of hard X-ray dark-field microscope using full-field optics

    International Nuclear Information System (INIS)

    Takano, Hidekazu; Azuma, Hiroaki; Shimomura, Sho; Tsuji, Takuya; Tsusaka, Yoshiyuki; Kagoshima, Yasushi

    2016-01-01

    We develop a dark-field X-ray microscope using full-field optics based on a synchrotron beamline. Our setup consists of a condenser system and a microscope objective with an angular acceptance larger than that of the condenser. The condenser system is moved downstream from its regular position such that the focus of the condenser is behind the objective. The dark-field microscope optics are configured by excluding the converging beam from the condenser at the focal point. The image properties of the system are evaluated by observing and calculating a Siemens star test chart with 10 keV X-rays. Our setup allows easy switching to bright-field imaging. (author)

  7. Asymmetric Dimethylarginine Plasma Levels and Endothelial Function in Newly Diagnosed Type 2 Diabetic Patients

    Directory of Open Access Journals (Sweden)

    Francesco Perticone

    2012-10-01

    Full Text Available It is now well established that major risk factors for cardiovascular diseases (CVD impact upon endothelial function by decreasing nitric oxide (NO bioavailability. Asymmetric dimethylarginine (ADMA, an endogenous analog of l-arginine, is able to inhibit the activity of endothelial-NO synthase, promoting endothelial dysfunction. Type 2 diabetes (T2D is characterized by a reduced endothelium-dependent vasodilation and increased ADMA levels and ADMA is strongly associated with micro- and macrovascular diabetic complications. However, there are not a lot of data about the role of ADMA on endothelial function in newly diagnosed T2D patients without cardiovascular (CV complications. For this aim, we have enrolled forty-five newly diagnosed T2D patients, evaluated by a oral glucose tolerance test, and thirty normal subjects. Endothelium-dependent and -independent vasodilatation was investigated by intra-arterial infusion of increasing doses of acetylcholine (ACh and sodium nitroprusside. ADMA was measured by high-performance liquid chromatography and insulin resistance (IR by HOMA. Newly diagnosed T2D patients showed higher ADMA and l-arginine mean values in comparison with normal subjects and a significantly reduced ACh-stimulated forearm blood flow (FBF. In T2D patients FBF was significantly and inversely correlated with ADMA (r = −0.524, p < 0.0001 and in a multivariate regression analysis, ADMA resulted the stronger predictor of FBF, explaining the 27.5% of variability (p < 0.0001. In conclusion, ADMA was strongly related to endothelial dysfunction also in patients with newly diagnosed T2D, without clinically manifest vascular complications. This field is of great interest for understanding the mechanisms underlying the pathogenesis of diabetic disease and its CV complications.

  8. Experimental test of a newly developed single-moderator, multi-detector, directional neutron spectrometer in reference monochromatic fields from 144 keV to 16.5 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Bedogni, R., E-mail: roberto.bedogni@lnf.infn.it [INFN – LNF, via E. Fermi n. 40, 00044 Frascati (Roma) (Italy); Gómez-Ros, J.M. [INFN – LNF, via E. Fermi n. 40, 00044 Frascati (Roma) (Italy); CIEMAT, Av. Complutense 40, 28040 Madrid (Spain); Pola, A.; Bortot, D. [Politecnico di Milano, Dipartimento di Energia, via La Masa 34, 20156 Milano (Italy); INFN – Milano, Via Celoria 16, 20133 Milano (Italy); Gentile, A. [INFN – LNF, via E. Fermi n. 40, 00044 Frascati (Roma) (Italy); Introini, M.V. [Politecnico di Milano, Dipartimento di Energia, via La Masa 34, 20156 Milano (Italy); INFN – Milano, Via Celoria 16, 20133 Milano (Italy); Buonomo, B. [INFN – LNF, via E. Fermi n. 40, 00044 Frascati (Roma) (Italy); Lorenzoli, M. [Politecnico di Milano, Dipartimento di Energia, via La Masa 34, 20156 Milano (Italy); INFN – Milano, Via Celoria 16, 20133 Milano (Italy); Mazzitelli, M. [INFN – LNF, via E. Fermi n. 40, 00044 Frascati (Roma) (Italy); Sacco, D. [INFN – LNF, via E. Fermi n. 40, 00044 Frascati (Roma) (Italy); INAIL – DPIA, Via di Fontana Candida n.1, 00040 Monteporzio Catone (Italy)

    2015-05-11

    A new directional neutron spectrometer called CYSP (CYlindrical SPectrometer) was developed within the NESCOFI@BTF (2011–2013) collaboration. The device, composed by seven active thermal neutron detectors located along the axis of a cylindrical moderator, was designed to simultaneously respond from the thermal domain up to hundreds of MeV neutrons. The new spectrometer condenses the performance of the Bonner Sphere Spectrometer in a single moderator; thus requiring only one exposure to determine the whole spectrum. The CYSP response matrix, determined with MCNP, has been experimentally evaluated with monochromatic reference neutron fields from 144 keV to 16.5 MeV, plus a {sup 252}Cf source, available at NPL (Teddington, UK). The results of the experiment confirmed the correctness of the response matrix within an overall uncertainty of ±2.5%. The new active spectrometer CYSP offers an innovative option for real-time monitoring of directional neutron fields as those produced in neutron beam-lines.

  9. Screening of Geomechanical Risks for Malaysian Development Field

    Directory of Open Access Journals (Sweden)

    Syed Najmuddin Syed Muhammad Syafiq

    2017-01-01

    Full Text Available Deeper drilling and exploitation of difficult reservoir is the new trend in oil and gas industry. Geomechanics study has, therefore, become a new requirement particularly for oil and gas field development. However, a complete geomechanics study is limited with the number of experts, time consuming and not a straightforward task. Therefore, there is an urgent need of a quick geomechanics screening criterion to be used as a standard guideline to evaluate the high level geomechanical risks and suitable analysis can be recommended for the identified development fields. The aim of this paper is to propose a screening criterion for geomechanical risks study based on four key parameters, drilling, depletion, injection and storage and sand production. The screening approach is designed based on Risk Assessment Matrix (RAM risk screening where the likelihood is based on a set of scores developed to specific questions. The consequence for each failure scenarios is assessed based on educated estimation of the impact towards people, asset, environment and reputation. Recommendations for geomechanical study are made based on the severity of each failure category on the RAM risk matrix. Fourteen development fields in offshore Peninsular Malaysia, offshore Sarawak and offshore Sabah are selected for the assessment. Based on results, fields in offshore Sarawak and Sabah have higher potential for geomechacnical issues mainly because of their geological settings and formation characteristics. A set of geomechanical study is proposed for each individual field for prudent management of potential geomechanics risk associated with the depletion and EOR injection scheme planned for the fields.

  10. Newly released EIA-law. A palette of wishes?; Das neue UVP-Recht. Ein Wunschkonzert?

    Energy Technology Data Exchange (ETDEWEB)

    Feldmann, Ulrike

    2015-05-15

    The EU-directive on Environmental Impact Assessment (EIA) for certain public and private projects was once again amended in 2014 after controversial discussions, three previous modifications during 1985 and 2010 and an aggregation of all amendments within the EU-EIA-2011/92 directive. This newly released EU-EIA-directive 2014/52/EU (hereinafter RL 2014/52) is published within the EU-official journal EU L 124 p. 1 from 25.04.2014, came into force on 15. May 2014 and has to be adopted into international law until 16.05.2017. The modifications made are also valid, apart from certain exceptions, for licensing procedures (including decommissioning of nuclear power plants) in the field of nuclear energy, as far as they might have possible, significant environmental effects. The European EIA directive's 30th ''anniversary'' on 27.06.2015 raises the question, which substantial changes will come soon along with the newly released EU-EIA law. All in all it seems like if authorities and industry might get along with the newly released EU-EIA regulations. The responsible Federal Ministry for the Environment is already working on a first preliminary draft. It is under consideration if the EIA-regulation should be submitted additionally, beyond required amendments by EU-law, to a general revision. EIA-law remains exciting.

  11. A model for mentoring newly-appointed nurse educators in nursing education institutions in South Africa

    Directory of Open Access Journals (Sweden)

    Eunice Seekoe

    2014-02-01

    Full Text Available Background: South Africa transformed higher education through the enactment of the Higher Education Act (No. 101 of 1997. The researcher identified the need to develop a model for the mentoring of newly-appointed nurse educators in nursing education institutions in South Africa. Objectives: To develop and describe the model for mentoring newly-appointed nurse educators in nursing education institutions in South Africa. Method: A qualitative and theory-generating design was used (following empirical findings regarding needs analysis in order to develop the model. The conceptualisation of the framework focused on the context, content, process and the theoretical domains that influenced the model. Ideas from different theories were borrowed from and integrated with the literature and deductive and inductive strategies were applied. Results: The structure of the model is multidimensional and complex in nature (macro, mesoand micro based on the philosophy of reflective practice, competency-based practice andcritical learning theories. The assumptions are in relation to stakeholders, context, mentoring, outcome, process and dynamic. The stakeholders are the mentor and mentee within an interactive participatory relationship. The mentoring takes place within the process with a sequence of activities such as relationship building, development, engagement, reflective process and assessment. Capacity building and empowerment are outcomes of mentoring driven by motivation. Conclusion: The implication for nurse managers is that the model can be used to develop mentoring programmes for newly-appointed nurse educators.

  12. Los Alamos Plutonium Facility newly generated TRU waste certification

    International Nuclear Information System (INIS)

    Gruetzmacher, K.; Montoya, A.; Sinkule, B.; Maez, M.

    1997-01-01

    This paper presents an overview of the activities being planned and implemented to certify newly generated contact handled transuranic (TRU) waste produced by Los Alamos National Laboratory's (LANL's) Plutonium Facility. Certifying waste at the point of generation is the most important cost and labor saving step in the WIPP certification process. The pedigree of a waste item is best known by the originator of the waste and frees a site from expensive characterization activities such as those associated with legacy waste. Through a cooperative agreement with LANLs Waste Management Facility and under the umbrella of LANLs WIPP-related certification and quality assurance documents, the Plutonium Facility will be certifying its own newly generated waste. Some of the challenges faced by the Plutonium Facility in preparing to certify TRU waste include the modification and addition of procedures to meet WIPP requirements, standardizing packaging for TRU waste, collecting processing documentation from operations which produce TRU waste, and developing ways to modify waste streams which are not certifiable in their present form

  13. Phenology of Lymantria monacha (Lepidoptera:Lymantriidae) laboratory reared on spruce foliage or a newly developed artificial diet

    Science.gov (United States)

    Melody A. Keena; Alice Vandel; Oldrich. Pultar

    2010-01-01

    Lymantria monacha (L.) (Lepidoptera: Lymantriidae) is a Eurasian pest of conifers that has potential for accidental introduction into North America. The phenology over the entire life cycle for L. monacha individuals from the Czech Republic was compared on Picea glauca (Moench) Voss (white spruce) and a newly...

  14. Problems faced by newly diagnosed diabetes mellitus patients at ...

    African Journals Online (AJOL)

    Diabetes mellitus can be a frightening experience for newly diagnosed patients. The aim of this study was to determine and describe the problems faced by newly diagnosed diabetes mellitus patients at primary healthcare facilities at Mopani district, Limpopo Province. A qualitative, descriptive and contextual research ...

  15. Newly graduated nurses' use of knowledge sources in clinical decision-making

    DEFF Research Database (Denmark)

    Voldbjerg, Siri Lygum; Grønkjaer, Mette; Wiechula, Rick

    2017-01-01

    AIMS AND OBJECTIVES: To explore which knowledge sources newly graduated nurses' use in clinical decision-making and why and how they are used. BACKGROUND: In spite of an increased educational focus on skills and competencies within evidence based practice newly graduated nurses' ability to use...... approaches to strengthen the knowledgebase used in clinical decision-making. DESIGN AND METHODS: Ethnographic study using participant-observation and individual semi-structured interviews of nine Danish newly graduated nurses in medical and surgical hospital settings. RESULTS: Newly graduates use...... in clinical decision-making. If newly graduates are to be supported in an articulate and reflective use of a variety of sources, they have to be allocated to experienced nurses who model a reflective, articulate and balanced use of knowledge sources. This article is protected by copyright. All rights reserved....

  16. Newly graduated nurses' occupational commitment and its associations with professional competence and work-related factors.

    Science.gov (United States)

    Numminen, Olivia; Leino-Kilpi, Helena; Isoaho, Hannu; Meretoja, Riitta

    2016-01-01

    To explore newly graduated nurses' occupational commitment and its associations with their self-assessed professional competence and other work-related factors. As a factor affecting nurse turnover, newly graduated nurses' occupational commitment and its associations with work-related factors needs exploring to retain adequate workforce. Nurses' commitment has mainly been studied as organisational commitment, but newly graduated nurses' occupational commitment and its association with work-related factors needs further studying. This study used descriptive, cross-sectional, correlation design. A convenience sample of 318 newly graduated nurses in Finland participated responding to an electronic questionnaire. Statistical software, NCSS version 9, was used in data analysis. Frequencies, percentages, ranges, means and standard deviations summarised the data. Multivariate Analyses of Variance estimated associations between occupational commitment and work-related variables. IBM SPSS Amos version 22 estimated the model fit of Occupational Commitment Scale and Nurse Competence Scale. Newly graduated nurses' occupational commitment was good, affective commitment reaching the highest mean score. There was a significant difference between the nurse groups in favour of nurses at higher competence levels in all subscales except in limited alternatives occupational commitment. Multivariate analyses revealed significant associations between subscales of commitment and competence, turnover intentions, job satisfaction, earlier professional education and work sector, competence counting only through affective dimension. The association between occupational commitment and low turnover intentions and satisfaction with nursing occupation was strong. Higher general competence indicated higher overall occupational commitment. Managers' recognition of the influence of all dimensions of occupational commitment in newly graduated nurses' professional development is important. Follow

  17. Ethical climate and nurse competence - newly graduated nurses' perceptions.

    Science.gov (United States)

    Numminen, Olivia; Leino-Kilpi, Helena; Isoaho, Hannu; Meretoja, Riitta

    2015-12-01

    is also a need for knowledge of newly graduated nurses' views of factors which act as enhancers or barriers to positive ethical climates to develop. Interventions, continuing education courses, and discussions designed to promote positive ethical climates should be developed for managers, nurses, and multi-professional teams. © The Author(s) 2014.

  18. Practices influenced by policy? An exploration of newly hired science teachers at sites in South Africa and the United States

    Science.gov (United States)

    Navy, S. L.; Luft, J. A.; Toerien, R.; Hewson, P. W.

    2018-05-01

    In many parts of the world, newly hired science teachers' practices are developing in a complex policy environment. However, little is known about how newly hired science teachers' practices are enacted throughout a cycle of instruction and how these practices can be influenced by macro-, meso-, and micro-policies. Knowing how policies impact practice can result in better policies or better support for certain policies in order to enhance the instruction of newly hired teachers. This comparative study investigated how 12 newly hired science teachers at sites in South Africa (SA) and the United States (US) progressed through an instructional cycle of planning, teaching, and reflection. The qualitative data were analysed through beginning teacher competency frameworks, the cycle of instruction, and institutional theory. Data analysis revealed prevailing areas of practice and connections to levels of policy within the instructional cycle phases. There were some differences between the SA and US teachers and among first-, second-, and third-year teachers. More importantly, this study indicates that newly hired teachers are susceptible to micro-policies and are progressively developing their practice. It also shows the importance of meso-level connectors. It suggests that teacher educators and policy makers must consider how to prepare and support newly hired science teachers to achieve the shared global visions of science teaching.

  19. NEWLY-PACKAGED BALI TOURIST PERFORMING ARTS IN THE PERSPECTIVE OF CULTURAL STUDIES

    Directory of Open Access Journals (Sweden)

    Ni Made Ruastiti

    2012-11-01

    Full Text Available This research is focused on the newly packaged tourist performing arts; they are anew concept and seem to be different from the general tourist performing arts. They arepackaged from various components of Balinese arts and managed as large scale-touristperforming arts in terms of materials, space, and time of their performances. The researchercalls them new types of Bali tourist performing arts because how they are presented isnew and different from the traditional tourist performing arts which are simply performed.In this research, the newly-packaged performing arts are analyzed in the perspective ofcultural studies.The research was carried out at three palaces in Bali; they are Mengwi Palace inBadung regency, Anyar Palace at Kerambitan, Tabanan regency, and Banyuning Palace atBongkasa, Badung regency. There are three main problems to be discussed: firstly, how dothe tourist performing arts emerge in all the palaces? Secondly, are they related to thetourist industry developed in the palaces?, thirdly, what is the impact and meaning of themfor the sake of the palaces, society, and Balinese culture? The researcher uses a qualitativemethod and an interdisciplinary approach as characteristics of cultural studies. The theoriesused are hegemony, deconstruction, and structuration.The result shows that the tourism development at all the palaces has made the localsociety become more critical. The money-oriented economy based on the spirit of gettingbenefit has made the emergence of comodification in all sectors of life. The emergence oftourist industry at the palaces has led to the idea of showing all of the useful art and culturalpotentials which at the palaces and their surroundings. Theoretically, the palaces can bestated to have deconstructed the concept of presenting the Bali tourist performing arts into anew one, that is, “the newly packaged Bali tourist performing arts”.It has been observed that all the palaces have developed t “Newly

  20. Efficacy of Intra-articular Injection of a Newly Developed Plasma Rich in Growth Factor (PRGF) Versus Hyaluronic Acid on Pain and Function of Patients with Knee Osteoarthritis: A Single-Blinded Randomized Clinical Trial.

    Science.gov (United States)

    Raeissadat, Seyed Ahmad; Rayegani, Seyed Mansoor; Ahangar, Azadeh Gharooee; Abadi, Porya Hassan; Mojgani, Parviz; Ahangar, Omid Gharooi

    2017-01-01

    Knee osteoarthritis is the most common joint disease. We aimed to compare the efficacy and safety of intra-articular injection of a newly developed plasma rich in growth factor (PRGF) versus hyaluronic acid (HA) on pain and function of patients with knee osteoarthritis. In this single-blinded randomized clinical trial, patients with symptomatic osteoarthritis of knee were assigned to receive 2 intra-articular injections of our newly developed PRGF in 3 weeks or 3 weekly injections of HA. Our primary outcome was the mean change from baseline until 2 and 6 months post intervention in scores of visual analog scale, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and Lequesne index. We used analysis of variance for repeated-measures statistical test. A total of 69 patients entered final analysis. The mean age of patients was 58.2 ± 7.41 years and 81.2% were women. In particular, total WOMAC index decreased from 42.9 ± 13.51 to 26.8 ± 13.45 and 24.4 ± 16.54 at 2 and 6 months in the newly developed PRGF group (within subjects P  = .001), and from 38.8 ± 12.62 to 27.8 ± 11.01 and 27.4 ± 11.38 at 2 and 6 months in the HA group (within subjects P  = .001), respectively (between subjects P  = .631). There was no significant difference between PRGF and HA groups in patients' satisfaction and minor complications of injection, whereas patients in HA group reported significantly lower injection-induced pain. In 6 months follow up, our newly developed PRGF and HA, both are effective options to decrease pain and improvement of function in patients with symptomatic mild to moderate knee osteoarthritis.

  1. 'Ephemerality’ in game development: opportunitiees and challenges

    OpenAIRE

    Fernández-Leiva, Antonio J.; Vázquez-Núñez, Ariel Eduardo

    2016-01-01

    Ephemeral Computation (Eph-C) is a newly created computation paradigm, the purpose of which is to take advantage of the ephemeral nature (limited lifetime) of computational resources. First we speak of this new paradigm in general terms, then more specifically in terms of videogame development. We present possible applications and benefits for the main research fields associated with videogame development. This is a preliminary work which aims to investigate the possibilities of applyin...

  2. Experimental Development of Low-emittance Field-emission Electron Sources

    Energy Technology Data Exchange (ETDEWEB)

    Lueangaranwong, A. [Northern Illinois Univ., DeKalb, IL (United States). Northern Illinois Center for Accelerator & Detector Development; Buzzard, C. [Northern Illinois Univ., DeKalb, IL (United States); Divan, R. [Argonne National Lab. (ANL), Argonne, IL (United States). Center for Nanoscale Materials; Korampally, V. [Northern Illinois Univ., DeKalb, IL (United States); Piot, P. [Northern Illinois Univ., DeKalb, IL (United States). Northern Illinois Center for Accelerator & Detector Development; Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)

    2016-10-10

    Field emission electron sources are capable of extreme brightness when excited by static or time-dependent electro- magnetic fields. We are currently developing a cathode test stand operating in DC mode with possibility to trigger the emission using ultra-short (~ 100-fs) laser pulses. This contribution describes the status of an experiment to investigate field-emission using cathodes under development at NIU in collaboration with the Argonne’s Center for Nanoscale Materials.

  3. Generation of a field development plan, North Field, North Oman

    International Nuclear Information System (INIS)

    Bostock, D.R.; Adams, S.; Mercadier, C.; Milatz, H.; van der Weerd, H.; Walker, T.

    1991-01-01

    This paper reports on the Natih Field in North Oman which is a complex domal fractured limestone structure with a STOIIP of some 50 million m 3 . Initially subjected to a depletion drive, rapidly dropping pressures resulted in a switch to water injection and then to gas injection to promote gas oil gravity drainage. In determining which production mechanism to promote an integrated approach has been taken. Field tests used tracers to investigate the problems associated with water injection; fracture orientation and intensity has been determined using core data including palaeomagnetics, FMS logs and out-crop studies; initial oil saturations have been determined within a give range using resistivity and pulsed neutron logs as well as capillary pressure curves to overcome problems of mixed wettability; to monitor gas saturation development in the matrix recourse has been made to Borehole Gravity Meter; special core analysis on restored state cores has been utilized to characterize wettability and relative permeability as input to both monitoring the water influx and to reservoir simulation. Development of a simulator to incorporate all the necessary physics of gravity drainage, including block to block interaction, has been undertaken at the research laboratories in the Netherlands and, using the understanding of the field built up through the above studies, a successful history match was achieved

  4. [Bioethical analysis of the use of newly dead patients in medical learning].

    Science.gov (United States)

    Gomes, Andréia Patrícia; Rego, Sergio; Palácios, Marisa; Siqueira-Batista, Rodrigo

    2010-01-01

    The purpose of this article is to carry out, a discussion on the subject of bioethics and cadavers based upon a critic review of literature. A review of literature, was made with a survey of articles between 1977 and 2007 in the sites 'Biblioteca Virtual de Saúde', PubMed and SciElo, utilizing the keywords: newly deceased patients, newly dead patients, simulators,. This was complemented by a critical evaluation of books published in the area of ethics and bioethics. The possibility to develop learning without orientation by a supervisor is doubtful.. The utilization of newly dead for learning invasive procedures is very frequent and seldom admitted. These procedures, are usually, carried out secretly, without the knowledge and consent of the family. The ethical aspects of these practices are not discussed in the practical medical education. It essential that the ethics of use of recent deceased become a necessary content of graduate education. Performance of these procedures by students should always be authorized by family members. The simulators meet the requirements of training. Discussions about the ethical and bioethical aspects cannot be separated from practical considerations during the students learning time.

  5. Demonstration of glucose-6-phosphate dehydrogenase in rat Kupffer cells by a newly-developed ultrastructural enzyme-cytochemistry

    Directory of Open Access Journals (Sweden)

    S Matsubara

    2009-06-01

    Full Text Available Although various tissue macrophages possess high glucose- 6-phosphate dehydrogenase (G6PD activity, which is reported to be closely associated with their phagocytotic/bactericidal function, the fine subcellular localization of this enzyme in liver resident macrophages (Kupffer cells has not been determined.We have investigated the subcellular localization of G6PD in Kupffer cells in rat liver, using a newly developed enzyme-cytochemical (copper-ferrocyanide method. Electron-dense precipitates indicating G6PD activity were clearly visible in the cytoplasm and on the cytosolic side of the endoplasmic reticulum of Kupffer cells. Cytochemical controls ensured specific detection of the enzymatic activity. Rat Kupffer cells abundantly possessed enzyme-cytochemically detectable G6PD activity. Kupffer cell G6PD may play a role in liver defense by delivering NADPH to NADPH-dependent enzymes. G6PD enzyme-cytochemistry may be a useful tool for the study of Kupffer cell functions.

  6. R/D and implement of temper bead welding as newly developed maintenance technique in nuclear power plant

    International Nuclear Information System (INIS)

    Hirano, Shinro; Sera, Takehiko; Chigusa, Naoki; Okimura, Koji; Nishimoto, Kazutoshi

    2011-01-01

    Japanese government has recently addressed a policy to increase capacity factor of existing nuclear PPs to achieve the goal to decrease the emission of CO 2 . Numerous preventive measures have taken in nuclear power plants to minimize the risk of unexpected long shutdown. Newly developed mitigation measures or repair methods need to be qualified to satisfy regulatory standards, before it is implemented to nuclear power plants. The qualification process needs to comply regulatory standards though it may consume time to go through each of the required steps. This paper describes such cases namely ambient temper-bead welding and clarifies the issues that need to be resolved regarding qualification process. The qualification process for new methods that has not been prescribed in regulatory standards temporarily completed by go through confirm testing by JAPEIC, RNP and issuance of no action letter in rush. Currently, the qualification process can only be applied on limited area so generalized qualification process needs to be established. (author)

  7. 10-GHz return-to-zero pulse source tunable in wavelength with a single- or multiwavelength output based on four-wave mixing in a newly developed highly nonlinear fiber

    DEFF Research Database (Denmark)

    Clausen, A. T.; Oxenlowe, L.; Peucheret, Christophe

    2001-01-01

    In this letter, a novel scheme for a wavelength-tunable pulse source (WTPS) is proposed and characterized. It is based on four-wave mixing (FWM) in a newly developed highly nonlinear fiber between a return-to-zero (RZ) pulsed signal at a fixed wavelength and a continuous wave probe tunable...

  8. PREVALENCE OF SLEEP DISORDERED BREATHING IN PATIENTS WITH NEWLY DIAGNOSED ACROMEGALY

    Directory of Open Access Journals (Sweden)

    U. A. Tsoy

    2014-01-01

    Full Text Available Background: Obstructive sleep disordered breathing or obstructive sleep apnea (OSA is the most common respiratory impairment in acromegaly. OSA is bound up with heightened cardiovascular mortality. Aim: Тo study frequency, features, and structure of sleep disordered breathing in patients with newly diagnosed acromegaly and to elucidate the factors influencing their development. Materials and methods: 38 patients (10 men, 28 women, median age 53 (28-76 years, median body mass index (BMI 29 (19.9-44.3 kg/m² with newly diagnosed acromegaly were recruited into the study. All subjects underwent full polysomnography (Embla N7000, Natus, USA and Remlogica software (USA. Results: Sleep disordered breathing was found in 28 (73.7% patients. OSA was revealed in all cases, in 11 (39.3% subjects it was mixed. In 10 (35.7% patients OSA was mild, in 8 (28.6% moderate, and in 10 (35.7% severe. BMI (р<0.01, disease duration (р=0.003, and insulin-like growth factor-1 (IGF-1 level (р=0.04 were different in patients without OSA and patients with moderate-to-severe OSA. No difference was found in sex (р=0.4, age (р=0.064, and growth hormone level (р=0.6. Frequency of arterial hypertension, diabetes mellitus, and other glucose metabolism impairments was the same in subjects without OSA and with severe-to-moderate OSA. Conclusion: All patients with newly diagnosed acromegaly should undergo polysomnography. BMI, disease duration, and IGF-1 level are significant risk factors for OSA development. Correlation OSA with arterial hypertension and glucose metabolism impairments needs to be further investigated.

  9. Application of a newly developed software program for image quality assessment in cone-beam computed tomography.

    Science.gov (United States)

    de Oliveira, Marcus Vinicius Linhares; Santos, António Carvalho; Paulo, Graciano; Campos, Paulo Sergio Flores; Santos, Joana

    2017-06-01

    The purpose of this study was to apply a newly developed free software program, at low cost and with minimal time, to evaluate the quality of dental and maxillofacial cone-beam computed tomography (CBCT) images. A polymethyl methacrylate (PMMA) phantom, CQP-IFBA, was scanned in 3 CBCT units with 7 protocols. A macro program was developed, using the free software ImageJ, to automatically evaluate the image quality parameters. The image quality evaluation was based on 8 parameters: uniformity, the signal-to-noise ratio (SNR), noise, the contrast-to-noise ratio (CNR), spatial resolution, the artifact index, geometric accuracy, and low-contrast resolution. The image uniformity and noise depended on the protocol that was applied. Regarding the CNR, high-density structures were more sensitive to the effect of scanning parameters. There were no significant differences between SNR and CNR in centered and peripheral objects. The geometric accuracy assessment showed that all the distance measurements were lower than the real values. Low-contrast resolution was influenced by the scanning parameters, and the 1-mm rod present in the phantom was not depicted in any of the 3 CBCT units. Smaller voxel sizes presented higher spatial resolution. There were no significant differences among the protocols regarding artifact presence. This software package provided a fast, low-cost, and feasible method for the evaluation of image quality parameters in CBCT.

  10. Application of a newly developed software program for image quality assessment in cone-beam computed tomography

    International Nuclear Information System (INIS)

    De Oliveira, Marcus Vinicius Linhares; Campos, Paulo Sergio Flores; Paulo, Graciano; Santos, Antonio Carvalho; Santos, Joana

    2017-01-01

    The purpose of this study was to apply a newly developed free software program, at low cost and with minimal time, to evaluate the quality of dental and maxillofacial cone-beam computed tomography (CBCT) images. A polymethyl methacrylate (PMMA) phantom, CQP-IFBA, was scanned in 3 CBCT units with 7 protocols. A macro program was developed, using the free software ImageJ, to automatically evaluate the image quality parameters. The image quality evaluation was based on 8 parameters: uniformity, the signal-to-noise ratio (SNR), noise, the contrast-to-noise ratio (CNR), spatial resolution, the artifact index, geometric accuracy, and low-contrast resolution. The image uniformity and noise depended on the protocol that was applied. Regarding the CNR, high-density structures were more sensitive to the effect of scanning parameters. There were no significant differences between SNR and CNR in centered and peripheral objects. The geometric accuracy assessment showed that all the distance measurements were lower than the real values. Low-contrast resolution was influenced by the scanning parameters, and the 1-mm rod present in the phantom was not depicted in any of the 3 CBCT units. Smaller voxel sizes presented higher spatial resolution. There were no significant differences among the protocols regarding artifact presence. This software package provided a fast, low-cost, and feasible method for the evaluation of image quality parameters in CBCT

  11. Application of a newly developed software program for image quality assessment in cone-beam computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    De Oliveira, Marcus Vinicius Linhares; Campos, Paulo Sergio Flores [Federal Institute of Bahia, Salvador (Brazil); Paulo, Graciano; Santos, Antonio Carvalho; Santos, Joana [Coimbra Health School, Polytechnic Institute of Coimbra, Coimbra (Portugal)

    2017-06-15

    The purpose of this study was to apply a newly developed free software program, at low cost and with minimal time, to evaluate the quality of dental and maxillofacial cone-beam computed tomography (CBCT) images. A polymethyl methacrylate (PMMA) phantom, CQP-IFBA, was scanned in 3 CBCT units with 7 protocols. A macro program was developed, using the free software ImageJ, to automatically evaluate the image quality parameters. The image quality evaluation was based on 8 parameters: uniformity, the signal-to-noise ratio (SNR), noise, the contrast-to-noise ratio (CNR), spatial resolution, the artifact index, geometric accuracy, and low-contrast resolution. The image uniformity and noise depended on the protocol that was applied. Regarding the CNR, high-density structures were more sensitive to the effect of scanning parameters. There were no significant differences between SNR and CNR in centered and peripheral objects. The geometric accuracy assessment showed that all the distance measurements were lower than the real values. Low-contrast resolution was influenced by the scanning parameters, and the 1-mm rod present in the phantom was not depicted in any of the 3 CBCT units. Smaller voxel sizes presented higher spatial resolution. There were no significant differences among the protocols regarding artifact presence. This software package provided a fast, low-cost, and feasible method for the evaluation of image quality parameters in CBCT.

  12. Distributed acoustic sensing technique and its field trial in SAGD well

    Science.gov (United States)

    Han, Li; He, Xiangge; Pan, Yong; Liu, Fei; Yi, Duo; Hu, Chengjun; Zhang, Min; Gu, Lijuan

    2017-10-01

    Steam assisted gravity drainage (SAGD) is a very promising way for the development of heavy oil, extra heavy oil and tight oil reservoirs. Proper monitoring of the SAGD operations is essential to avoid operational issues and improve efficiency. Among all the monitoring techniques, micro-seismic monitoring and related interpretation method can give useful information about the steam chamber development and has been extensively studied. Distributed acoustic sensor (DAS) based on Rayleigh backscattering is a newly developed technique that can measure acoustic signal at all points along the sensing fiber. In this paper, we demonstrate a DAS system based on dual-pulse heterodyne demodulation technique and did field trial in SAGD well located in Xinjiang Oilfield, China. The field trail results validated the performance of the DAS system and indicated its applicability in steam-chamber monitoring and hydraulic monitoring.

  13. Innovative IPV from attenuated Sabin poliovirus or newly designed alternative seed strains.

    Science.gov (United States)

    Hamidi, Ahd; Bakker, Wilfried A M

    2012-11-01

    This article gives an overview of the patent literature related to innovative inactivated polio vaccine (i-IPV) based on using Sabin poliovirus strains and newly developed alternative recombinant poliovirus strains. This innovative approach for IPV manufacturing is considered to attribute to the requirement for affordable IPV in the post-polio-eradication era, which is on the horizon. Although IPV is a well-established vaccine, the number of patent applications in this field was seen to have significantly increased in the past decade. Currently, regular IPV appears to be too expensive for universal use. Future affordability may be achieved by using alternative cell lines, alternative virus seed strains, improved and optimized processes, dose sparing, or the use of adjuvants. A relatively short-term option to achieve cost-price reduction is to work on regular IPV, using wild-type poliovirus strains, or on Sabin-IPV, based on using attenuated poliovirus strains. This price reduction can be achieved by introducing efficiency in processing. There are also multiple opportunities to work on dose sparing, for example, by using adjuvants or fractional doses. Renewed interest in this field was clearly reflected in the number and diversity of patent applications. In a later stage, several innovative approaches may become even more attractive, for example the use of recombinant virus strains or even a totally synthetic vaccine. Currently, such work is mainly carried out by research institutes and universities and therefore clinical data are not available.

  14. Newly Generated Liquid Waste Processing Alternatives Study, Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    Landman, William Henry; Bates, Steven Odum; Bonnema, Bruce Edward; Palmer, Stanley Leland; Podgorney, Anna Kristine; Walsh, Stephanie

    2002-09-01

    This report identifies and evaluates three options for treating newly generated liquid waste at the Idaho Nuclear Technology and Engineering Center of the Idaho National Engineering and Environmental Laboratory. The three options are: (a) treat the waste using processing facilities designed for treating sodium-bearing waste, (b) treat the waste using subcontractor-supplied mobile systems, or (c) treat the waste using a special facility designed and constructed for that purpose. In studying these options, engineers concluded that the best approach is to store the newly generated liquid waste until a sodium-bearing waste treatment facility is available and then to co-process the stored inventory of the newly generated waste with the sodium-bearing waste. After the sodium-bearing waste facility completes its mission, two paths are available. The newly generated liquid waste could be treated using the subcontractor-supplied system or the sodium-bearing waste facility or a portion of it. The final decision depends on the design of the sodium-bearing waste treatment facility, which will be completed in coming years.

  15. Visual field defects after temporal lobe resection for epilepsy.

    Science.gov (United States)

    Steensberg, Alvilda T; Olsen, Ane Sophie; Litman, Minna; Jespersen, Bo; Kolko, Miriam; Pinborg, Lars H

    2018-01-01

    To determine visual field defects (VFDs) using methods of varying complexity and compare results with subjective symptoms in a population of newly operated temporal lobe epilepsy patients. Forty patients were included in the study. Two patients failed to perform VFD testing. Humphrey Field Analyzer (HFA) perimetry was used as the gold standard test to detect VFDs. All patients performed a web-based visual field test called Damato Multifixation Campimetry Online (DMCO). A bedside confrontation visual field examination ad modum Donders was extracted from the medical records in 27/38 patients. All participants had a consultation by an ophthalmologist. A questionnaire described the subjective complaints. A VFD in the upper quadrant was demonstrated with HFA in 29 (76%) of the 38 patients after surgery. In 27 patients tested ad modum Donders, the sensitivity of detecting a VFD was 13%. Eight patients (21%) had a severe VFD similar to a quadrant anopia, thus, questioning their permission to drive a car. In this group of patients, a VFD was demonstrated in one of five (sensitivity=20%) ad modum Donders and in seven of eight (sensitivity=88%) with DMCO. Subjective symptoms were only reported by 28% of the patients with a VFD and in two of eight (sensitivity=25%) with a severe VFD. Most patients (86%) considered VFD information mandatory. VFD continue to be a frequent adverse event after epilepsy surgery in the medial temporal lobe and may affect the permission to drive a car in at least one in five patients. Subjective symptoms and bedside visual field testing ad modum Donders are not sensitive to detect even a severe VFD. Newly developed web-based visual field test methods appear sensitive to detect a severe VFD but perimetry remains the golden standard for determining if visual standards for driving is fulfilled. Patients consider VFD information as mandatory. Copyright © 2017. Published by Elsevier Ltd.

  16. A genomic audit of newly-adopted autosomal STRs for forensic identification.

    Science.gov (United States)

    Phillips, C

    2017-07-01

    In preparation for the growing use of massively parallel sequencing (MPS) technology to genotype forensic STRs, a comprehensive genomic audit of 73 STRs was made in 2016 [Parson et al., Forensic Sci. Int. Genet. 22, 54-63]. The loci examined included miniSTRs that were not in widespread use, but had been incorporated into MPS kits or were under consideration for this purpose. The current study expands the genomic analysis of autosomal STRs that are not commonly used, to include the full set of developed miniSTRs and an additional 24 STRs, most of which have been recently included in several supplementary forensic multiplex kits for capillary electrophoresis. The genomic audit of these 47 newly-adopted STRs examined the linkage status of new loci on the same chromosome as established forensic STRs; analyzed world-wide population variation of the newly-adopted STRs using published data; assessed their forensic informativeness; and compiled the sequence characteristics, repeat structures and flanking regions of each STR. A further 44 autosomal STRs developed for forensic analyses but not incorporated into commercial kits, are also briefly described. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Application of the newly developed 3D transport code r3t to selected field cases

    International Nuclear Information System (INIS)

    Rubel, A.; Fein, E.

    2006-01-01

    To model the transport of contaminants in connexion with long-term safety analyses of repositories for radioactive waste recently the numerical model r 3 t was developed. In the following first applications of r 3 t are presented. The results of modelling of the transport of zinc at the sewage treatment facility in Cape Cod, Massachusetts, and of trace elements in the frame work of the in-situ diffusion experiments DI-A and DR at the underground laboratory Mont Terri are shown. (authors)

  18. Three-field modeling for MARS 1-D code

    International Nuclear Information System (INIS)

    Hwang, Moonkyu; Lim, Ho-Gon; Jeong, Jae-Jun; Chung, Bub-Dong

    2006-01-01

    In this study, the three-field modeling of the two-phase mixture is developed. The finite difference equations for the three-field equations thereafter are devised. The solution scheme has been implemented into the MARS 1-D code. The three-field formulations adopted are similar to those for MARS 3-D module, in a sense that the mass and momentum are treated separately for the entrained liquid and continuous liquid. As in the MARS-3D module, the entrained liquid and continuous liquid are combined into one for the energy equation, assuming thermal equilibrium between the two. All the non-linear terms are linearized to arrange the finite difference equation set into a linear matrix form with respect to the unknown arguments. The problems chosen for the assessment of the newly added entrained field consist of basic conceptual tests. Among the tests are gas-only test, liquid-only test, gas-only with supplied entrained liquid test, Edwards pipe problem, and GE level swell problem. The conceptual tests performed confirm the sound integrity of the three-field solver

  19. Observation of the bone mineral density of newly formed bone using rabbits. Compared with newly formed bone around implants and cortical bone

    International Nuclear Information System (INIS)

    Nakada, Hiroshi; Numata, Yasuko; Sakae, Toshiro; Tamaki, Hiroyuki; Kato, Takao

    2009-01-01

    There have been many studies reporting that newly formed bone around implants is spongy bone. However, although the morphology is reported as being like spongy bone, it is difficult to discriminate whether the bone quality of newly formed bone appears similar to osteoid or cortical bone; therefore, evaluation of bone quality is required. The aims of this study were to measure the bone mineral density (BMD) values of newly formed bone around implants after 4, 8, 16, 24 and 48 weeks, to represent these values on three-dimensional color mapping (3Dmap), and to evaluate the change in bone quality associated with newly formed bone around implants. The animal experimental protocol of this study was approved by the Ethics Committee for Animal Experiments of our University. This experiment used 20 surface treatment implants (Ti-6Al-4V alloy: 3.1 mm in diameter and 30.0 mm in length) by grit-blasting. They were embedded into surgically created flaws in femurs of 20 New Zealand white rabbits (16 weeks old, male). The rabbits were sacrificed with an ear intravenous overdose of pentobarbital sodium under general anesthesia each period, and the femurs were resected. We measured BMD of newly formed bone around implants and cortical bone using Micro-CT, and the BMD distribution map of 3Dmap (TRI/3D Bon BMD, Ratoc System Engineering). The BMD of cortical bone was 1,026.3±44.3 mg/cm 3 at 4 weeks, 1,023.8±40.9 mg/cm 3 at 8 weeks, 1,048.2±45.6 mg/cm 3 at 16 weeks, 1,067.2±60.2 mg/cm 3 at 24 weeks, and 1,069.3±50.7 mg/cm 3 at 48 weeks after implantation, showing a non-significant increase each period. The BMD of newly formed bone around implants was 296.8±25.6 mg/cm 3 at 4 weeks, 525.0±72.4 mg/cm 3 at 8 weeks, 691.2±26.0 mg/cm 3 at 16 weeks, 776.9±27.7 mg/cm 3 at 24 weeks, and 845.2±23.1 mg/cm 3 at 48 weeks after implantation, showing a significant increase after each period. It was revealed that the color scale of newly formed bone was Low level at 4 weeks, and then it

  20. Interpretation of field potentials measured on a multi electrode array in pharmacological toxicity screening on primary and human pluripotent stem cell-derived cardiomyocytes

    NARCIS (Netherlands)

    Tertoolen, L.G.J.; Braam, S. R.; van Meer, B.J.; Passier, R.; Mummery, C. L.

    2018-01-01

    Multi electrode arrays (MEAs) are increasingly used to detect external field potentials in electrically active cells. Recently, in combination with cardiomyocytes derived from human (induced) pluripotent stem cells they have started to become a preferred tool to examine newly developed drugs for

  1. Newly developed central diabetes insipidus following kidney transplantation: a case report.

    Science.gov (United States)

    Kim, K M; Kim, S M; Lee, J; Lee, S Y; Kwon, S K; Kim, H-Y

    2013-09-01

    Polyuria after kidney transplantation is a common, usually self-limiting disorder. However, persistent polyuria can cause not only patient discomfort, including polyuria and polydipsia, but also volume depletion that can produce allograft dysfunction. Herein, we have report a case of central diabetes insipidus newly diagnosed after kidney transplantation. A 45-year-old woman with end-stage kidney disease underwent deceased donor kidney transplantation. Two months after the transplantation, she was admitted for persistent polyuria, polydipsia, and nocturia with urine output of more than 4 L/d. Urine osmolarity was 100 mOsm/kg, which implied that the polyuria was due to water rather than solute diuresis. A water deprivation test was compatible with central diabetes insipidus; desmopressin treatment resulted in immediate symptomatic relief. Brain magnetic resonance imaging (MRI) demonstrated diffuse thickening of the pituitary stalk, which was considered to be nonspecific finding. MRI 12 months later showed no change in the pituitary stalk, although the patient has been in good health without polyuria or polydipsia on desmopressin treatment. The possibility of central diabetes insipidus should be considered in patients presenting with persistent polyuria after kidney transplantation. Copyright © 2013 Elsevier Inc. All rights reserved.

  2. Newly graduated nurses' use of knowledge sources: a meta-ethnography.

    Science.gov (United States)

    Voldbjerg, Siri Lygum; Grønkjaer, Mette; Sørensen, Erik Elgaard; Hall, Elisabeth O C

    2016-08-01

    To advance evidence on newly graduated nurses' use of knowledge sources. Clinical decisions need to be evidence-based and understanding the knowledge sources that newly graduated nurses use will inform both education and practice. Qualitative studies on newly graduated nurses' use of knowledge sources are increasing though generated from scattered healthcare contexts. Therefore, a metasynthesis of qualitative research on what knowledge sources new graduates use in decision-making was conducted. Meta-ethnography. Nineteen reports, representing 17 studies, published from 2000-2014 were identified from iterative searches in relevant databases from May 2013-May 2014. Included reports were appraised for quality and Noblit and Hare's meta-ethnography guided the interpretation and synthesis of data. Newly graduated nurses' use of knowledge sources during their first 2-year postgraduation were interpreted in the main theme 'self and others as knowledge sources,' with two subthemes 'doing and following' and 'knowing and doing,' each with several elucidating categories. The metasynthesis revealed a line of argument among the report findings underscoring progression in knowledge use and perception of competence and confidence among newly graduated nurses. The transition phase, feeling of confidence and ability to use critical thinking and reflection, has a great impact on knowledge sources incorporated in clinical decisions. The synthesis accentuates that for use of newly graduated nurses' qualifications and skills in evidence-based practice, clinical practice needs to provide a supportive environment which nurtures critical thinking and questions and articulates use of multiple knowledge sources. © 2016 John Wiley & Sons Ltd.

  3. SYBR green-based one step quantitative real-time polymerase chain reaction assay for the detection of Zika virus in field-caught mosquitoes.

    Science.gov (United States)

    Tien, Wei-Ping; Lim, Gareth; Yeo, Gladys; Chiang, Suzanna Nicole; Chong, Chee-Seng; Ng, Lee-Ching; Hapuarachchi, Hapuarachchige Chanditha

    2017-09-19

    The monitoring of vectors is one of the key surveillance measures to assess the risk of arbovirus transmission and the success of control strategies in endemic regions. The recent re-emergence of Zika virus (ZIKV) in the tropics, including Singapore, emphasizes the need to develop cost-effective, rapid and accurate assays to monitor the virus spread by mosquitoes. As ZIKV infections largely remain asymptomatic, early detection of ZIKV in the field-caught mosquitoes enables timely implementation of appropriate mosquito control measures. We developed a rapid, sensitive and specific real-time reverse transcription polymerase chain reaction (rRT-PCR) assay for the detection of ZIKV in field-caught mosquitoes. The primers and PCR cycling conditions were optimized to minimize non-specific amplification due to cross-reactivity with the genomic material of Aedes aegypti, Aedes albopictus, Culex quinquefasciatus, Culex tritaeniorhynchus, Culex sitiens and Anopheles sinensis, as well as accompanying microbiota. The performance of the assay was further evaluated with a panel of flaviviruses and alphaviruses as well as in field-caught Ae. aegypti mosquitoes confirmed to be positive for ZIKV. As compared to a probe-based assay, the newly developed assay demonstrated 100% specificity and comparable detection sensitivity for ZIKV in mosquitoes. Being a SYBR Green-based method, the newly-developed assay is cost-effective and easy to adapt, thus is applicable to large-scale vector surveillance activities in endemic countries, including those with limited resources and expertise. The amplicon size (119 bp) also allows sequencing to confirm the virus type. The primers flank relatively conserved regions of ZIKV genome, so that, the assay is able to detect genetically diverse ZIKV strains. Our findings, therefore, testify the potential use of the newly-developed assay in vector surveillance programmes for ZIKV in endemic regions.

  4. Four newly recorded species of Dryopteridaceae from Kashmir valley, India

    Directory of Open Access Journals (Sweden)

    SHAKOOR AHMAD MIR

    2014-04-01

    Full Text Available Mir SA, Mishra AK, Reshi ZA, Sharma MP. 2014. Four newly recorded species of Dryopteridaceae from Kashmir valley, India. Biodiversitas 15: 6-11. Habitat diversity, elevation, cloud cover, rainfall, seasonal and temperature variations have created many ideal sites for the luxuriant growth of pteridophytes in the Kashmir valley, yet all the regions of the valley have not been surveyed. In Kashmir valley the family Dryopteridaceae is represented by 31 species. During the recent extensive field surveys of Shopian district four more species viz., Dryopteris caroli-hopei Fraser-Jenkins, Dryopteris blanfordii subsp. nigrosquamosa (Ching Fraser-Jenkins, Dryopteris pulvinulifera (Bedd. Kuntze and Polystichum Nepalense (Spreng C. Chr. have been recorded for the first time from the valley. The taxonomic description, synonyms, distribution and photographs of each species are given in this article.

  5. The nanotoxicology of a newly developed zero-valent iron nanomaterial for groundwater remediation and its remediation efficiency assessment combined with in vitro bioassays for detection of dioxin-like environmental pollutants

    OpenAIRE

    Schiwy, Andreas Herbert

    2016-01-01

    The assessment of chemicals and new compounds is an important task of ecotoxicology. In this thesis a newly developed zero-valent iron material for nanoremediation of groundwater contaminations was investigated and in vitro bioassays for high throughput screening were developed. These two elements of the thesis were combined to assess the remediation efficiency of the nanomaterial on the groundwater contaminant acridine. The developed in vitro bioassays were evaluated for quantification of th...

  6. Certification document for newly generated contact-handled transuranic waste

    International Nuclear Information System (INIS)

    Box, W.D.; Setaro, J.

    1984-01-01

    The US Department of Energy has requested that all national laboratories handling defense waste develop and augment a program whereby all newly generated contact-handled transuranic (TRU) waste be contained, stored, and then shipped to the Waste Isolation Pilot Plant (WIPP) in accordance with the requirements set forth in WIPP-DOE-114. The program described in this report delineates how Oak Ridge National Laboratory intends to comply with these requirements and lists the procedures used by each generator to ensure that their TRU wastes are certifiable for shipment to WIPP

  7. Newly blind persons using virtual environment system in a traditional orientation and mobility rehabilitation program: a case study.

    Science.gov (United States)

    Lahav, Orly; Schloerb, David W; Srinivasan, Mandayam A

    2012-09-01

    This paper presents a virtual reality system (the BlindAid) developed for orientation and mobility training of people who are newly blind. The BlindAid allows users to interact with different virtual structures and objects via auditory and haptic feedback. This case study aims to examine if and how the BlindAid, in conjunction with a traditional rehabilitation programme, can help people who are newly blind develop new orientation and mobility methods. Follow-up research based on this study, with a large experiment and control group, could contribute to the area of orientation and mobility rehabilitation training for the newly blind. The case study research focused on A., a woman who is newly blind, for 17 virtual sessions spanning ten weeks, during the 12 weeks of her traditional orientation and mobility rehabilitation programme. The research was implemented by using virtual environment (VE) exploration and orientation tasks in VE and physical spaces. The research methodology used both qualitative and quantitative methods, including interviews, questionnaire, videotape recording, and user computer logs. The results of this study helped elucidate several issues concerning the contribution of the BlindAid system to the exploration strategies and learning processes experienced by the participant in her encounters with familiar and unfamiliar physical surroundings. [Box: see text].

  8. The impact of organisational culture on the adaptation of newly ...

    African Journals Online (AJOL)

    Usually newly employed nurses find adjusting to a work setting a challenging experience. Their successful adaptation to their work situation is greatly influenced by the socialisation process inherent in the organisational culture. The newly employed nurse often finds that the norms are unclear, confusing and restrictive.

  9. A newly developed spinal simulator.

    Science.gov (United States)

    Chester, R; Watson, M J

    2000-11-01

    A number of studies indicate poor intra-therapist and inter-therapist reliability in the performance of graded, passive oscillatory movements to the lumbar spine. However, it has been suggested that therapists can be trained to be more consistent in their performance of these techniques if given reliable quantitative feedback. The intention of this study was to develop equipment, analogous to the lumbar spine that could be used for both teaching and research purposes. Equipment has been updated and connected to a personal IBM compatible computer. Custom designed software allows concurrent and accurate feedback to students on their performance and in a form suitable for advanced data analysis using statistical packages. The uses and implications of this equipment are discussed. Copyright 2000 Harcourt Publishers Ltd.

  10. Autopolyploids in fodder grass breeding: induction and field performance

    Energy Technology Data Exchange (ETDEWEB)

    Dabkevičienė, G.; Kemešytė, V.; Statkevičiūtė, G.; Lemežienė, N.; Brazauskas, G.

    2017-07-01

    Doubling of chromosome set directly affects plant performance through increase of organ size, higher feeding value and increased resistance to adverse environmental factors. Therefore efficient methods of polyploid induction are needed in order to develop new varieties of naturally diploid fodder grass species. The efficiency of antimitotic agents as colchicine, amiprophos-methyl, trifluralin and oryzalin was compared in a series of tetraploid induction experiments in Lolium multiflorum, L. perenne and Festuca pratensis, while newly developed tetraploid plants were compared to standard tetraploid varieties in the field trials. Colchicine treatment proved to be the most efficient method for in vitro cultured embryos in comparison with the other agents. Induced tetraploids of F. pratensis produced higher dry matter and seed yield and could be used for the development of new varieties. Induced tetraploid plants of Lolium spp. were equal to the standard varieties in field trials, therefore they could be used as parental genotypes in crosses. Induced tetraploids of F. pratensis produced higher dry matter and seed yield and could be used for development of new variety.

  11. Encounters of Newly Qualified Teachers with Micro-Politics in Primary Schools in Zimbabwe

    Science.gov (United States)

    Magudu, Snodia; Gumbo, Mishack

    2017-01-01

    This article demonstrates, through the example of Zimbabwe, the complexities of micro-political learning during induction. It reports on the experiences of ten newly qualified teachers with micro-politics or power relations in their schools during induction and locates these experiences within the broader context of their professional development.…

  12. Teaching and Learning in the Tropics: An Epistemic Exploration of "the Field" in a Development Studies Field Trip

    Science.gov (United States)

    Patel, Kamna

    2015-01-01

    Development studies employs theories, tools and methods often found in geography, including the international field trip to a "developing" country. In 2013 and 2014, I led a two-week trip to Ethiopia. To better comprehend the effects of "the field" on students' learning, I introduced an assessed reflexive field diary to…

  13. Morphometric study of newly emerged unmated queens of honey bee Apis mellifera L. in Ismailia Governorate, Egypt

    Directory of Open Access Journals (Sweden)

    S.M. Kamel

    2013-06-01

    Full Text Available Recently, morphometric analysis is being a very good tool for identification of honey bee races and characterization of genetic materials. This fact has motivated the present work to investigate the effects of two grafting methods, three types of artificial queen wax cups and four periods of queen rearing on some morphological characters of newly emerged queens. The developed technique used in the present study depends on the integration between Scanner unit and Photoshop program, called Scan Photo Method (SPM. The measurements of 23 morphological characteristics of reared queens were estimated by using SPM. Results indicated significant differences between periods in the measurements of the studied characteristics on forewing such as cubital index, distance C, distance D, radial field, inner wing length, inner wing width, dumb bell index, distance I, II, III and IV, except cubital A and cubital B. Regarding the effects of cup types and grafting methods, data also revealed significant differences in all measurements of studied characteristics, except tibial length, hind wing length, cubital B, radial field and distance IV. Further works in this area were recommended to find out a relation between some morphometric characters and important of some quantitative characters.

  14. Assessment for markers of nephropathy in newly diagnosed type 2 ...

    African Journals Online (AJOL)

    Objective: To assess for markers of nephropathy in newly diagnosed type 2 diabetics, using blood pressure levels, endogenous creatinine clearance and urinary protein excretion as markers of renal disease. Study design: Ninety newly diagnosed type 2 diabetics were studied within 6 weeks of diagnosis. They were in ...

  15. Polymeric flat focal field arrayed waveguide grating using electron-beam direct writing

    Science.gov (United States)

    Lu, Si; Yan, Yingbai; Jin, Guofan; Wong, W. H.; Pun, E. Y. B.

    2004-06-01

    A four-channel 400-GHz spacing flat focal field arrayed waveguide grating (AWG) demultiplexer is designed based on polymeric optical waveguide. The waveguide core-layer material is a newly developed negative tone epoxy Novolak resin (ENR) polymer with ultravoilet (UV) cured resin Norland optical adhesive 61 (NOA61) as the cladding layer. The device is fabricated using electron-beam direct writing, which has less processing steps than the reported polymeric AWGs. The experimental result is presented.

  16. Efficacy of Intra-articular Injection of a Newly Developed Plasma Rich in Growth Factor (PRGF) Versus Hyaluronic Acid on Pain and Function of Patients with Knee Osteoarthritis: A Single-Blinded Randomized Clinical Trial

    Science.gov (United States)

    Raeissadat, Seyed Ahmad; Rayegani, Seyed Mansoor; Ahangar, Azadeh Gharooee; Abadi, Porya Hassan; Mojgani, Parviz; Ahangar, Omid Gharooi

    2017-01-01

    Background and objectives: Knee osteoarthritis is the most common joint disease. We aimed to compare the efficacy and safety of intra-articular injection of a newly developed plasma rich in growth factor (PRGF) versus hyaluronic acid (HA) on pain and function of patients with knee osteoarthritis. Methods: In this single-blinded randomized clinical trial, patients with symptomatic osteoarthritis of knee were assigned to receive 2 intra-articular injections of our newly developed PRGF in 3 weeks or 3 weekly injections of HA. Our primary outcome was the mean change from baseline until 2 and 6 months post intervention in scores of visual analog scale, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and Lequesne index. We used analysis of variance for repeated-measures statistical test. Results: A total of 69 patients entered final analysis. The mean age of patients was 58.2 ± 7.41 years and 81.2% were women. In particular, total WOMAC index decreased from 42.9 ± 13.51 to 26.8 ± 13.45 and 24.4 ± 16.54 at 2 and 6 months in the newly developed PRGF group (within subjects P = .001), and from 38.8 ± 12.62 to 27.8 ± 11.01 and 27.4 ± 11.38 at 2 and 6 months in the HA group (within subjects P = .001), respectively (between subjects P = .631). There was no significant difference between PRGF and HA groups in patients’ satisfaction and minor complications of injection, whereas patients in HA group reported significantly lower injection-induced pain. Conclusions: In 6 months follow up, our newly developed PRGF and HA, both are effective options to decrease pain and improvement of function in patients with symptomatic mild to moderate knee osteoarthritis. PMID:29051707

  17. Efficacy of Intra-articular Injection of a Newly Developed Plasma Rich in Growth Factor (PRGF Versus Hyaluronic Acid on Pain and Function of Patients with Knee Osteoarthritis: A Single-Blinded Randomized Clinical Trial

    Directory of Open Access Journals (Sweden)

    Seyed Ahmad Raeissadat

    2017-10-01

    Full Text Available Background and objectives: Knee osteoarthritis is the most common joint disease. We aimed to compare the efficacy and safety of intra-articular injection of a newly developed plasma rich in growth factor (PRGF versus hyaluronic acid (HA on pain and function of patients with knee osteoarthritis. Methods: In this single-blinded randomized clinical trial, patients with symptomatic osteoarthritis of knee were assigned to receive 2 intra-articular injections of our newly developed PRGF in 3 weeks or 3 weekly injections of HA. Our primary outcome was the mean change from baseline until 2 and 6 months post intervention in scores of visual analog scale, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC, and Lequesne index. We used analysis of variance for repeated-measures statistical test. Results: A total of 69 patients entered final analysis. The mean age of patients was 58.2 ± 7.41 years and 81.2% were women. In particular, total WOMAC index decreased from 42.9 ± 13.51 to 26.8 ± 13.45 and 24.4 ± 16.54 at 2 and 6 months in the newly developed PRGF group (within subjects P  = .001, and from 38.8 ± 12.62 to 27.8 ± 11.01 and 27.4 ± 11.38 at 2 and 6 months in the HA group (within subjects P  = .001, respectively (between subjects P  = .631. There was no significant difference between PRGF and HA groups in patients’ satisfaction and minor complications of injection, whereas patients in HA group reported significantly lower injection-induced pain. Conclusions: In 6 months follow up, our newly developed PRGF and HA, both are effective options to decrease pain and improvement of function in patients with symptomatic mild to moderate knee osteoarthritis.

  18. Numerical and analytical investigation towards performance enhancement of a newly developed rockfall protective cable-net structure

    Directory of Open Access Journals (Sweden)

    S. Dhakal

    2012-04-01

    Full Text Available In a previous companion paper, we presented a three-tier modelling of a particular type of rockfall protective cable-net structure (barrier, developed newly in Japan. Therein, we developed a three-dimensional, Finite Element based, nonlinear numerical model having been calibrated/back-calculated and verified with the element- and structure-level physical tests. Moreover, using a very simple, lumped-mass, single-degree-of-freedom, equivalently linear analytical model, a global-displacement-predictive correlation was devised by modifying the basic equation – obtained by combining the principles of conservation of linear momentum and energy – based on the back-analysis of the tests on the numerical model. In this paper, we use the developed models to explore the performance enhancement potential of the structure in terms of (a the control of global displacement – possibly the major performance criterion for the proposed structure owing to a narrow space available in the targeted site, and (b the increase in energy dissipation by the existing U-bolt-type Friction-brake Devices – which are identified to have performed weakly when integrated into the structure. A set of parametric investigations have revealed correlations to achieve the first objective in terms of the structure's mass, particularly by manipulating the wire-net's characteristics, and has additionally disclosed the effects of the impacting-block's parameters. Towards achieving the second objective, another set of parametric investigations have led to a proposal of a few innovative improvements in the constitutive behaviour (model of the studied brake device (dissipator, in addition to an important recommendation of careful handling of the device based on the identified potential flaw.

  19. Avoiding transport bottlenecks in an expanding root system: xylem vessel development in fibrous and pioneer roots under field conditions.

    Science.gov (United States)

    Bagniewska-Zadworna, Agnieszka; Byczyk, Julia; Eissenstat, David M; Oleksyn, Jacek; Zadworny, Marcin

    2012-09-01

    Root systems develop to effectively absorb water and nutrients and to rapidly transport these materials to the transpiring shoot. In woody plants, roots can be born with different functions: fibrous roots are primarily used for water and nutrient absorption, whereas pioneer roots have a greater role in transport. Because pioneer roots extend rapidly in the soil and typically quickly produce fibrous roots, they need to develop transport capacity rapidly so as to avoid becoming a bottleneck to the absorbed water of the developing fibrous roots and, as we hypothesized, immediately activate a specific type of autophagy at a precise time of their development. Using microscopy techniques, we monitored xylem development in Populus trichocarpa roots in the first 7 d after emergence under field conditions. Newly formed pioneer roots contained more primary xylem poles and had larger diameter tracheary elements than fibrous roots. While xylogenesis started later in pioneer roots than in fibrous, it was completed at the same time, resulting in functional vessels on the third to fourth day following root emergence. Programmed cell death was responsible for creating the water conducting capacity of xylem. Although the early xylogenesis processes were similar in fibrous and pioneer roots, secondary vascular development proceeded much more rapidly in pioneer roots. Compared to fibrous roots, rapid development of transport capacity in pioneer roots is not primarily caused by accelerated xylogenesis but by larger and more numerous tracheary elements and by rapid initiation of secondary growth.

  20. Accumulation of operational history through emulation test to meet proven technology requirement for newly developed I and C technology

    International Nuclear Information System (INIS)

    Yeong Cheol, Shin; Sung Kon, Kang; Han Seong, Son

    2006-01-01

    As new advanced digital I and C technology with potential benefits of higher functionality and better cost effectiveness is available in the market, NPP (Nuclear Power Plant) operators are inclined to use the new technology for the construction of new plant and the upgrade of existing plants. However, this new technology poses risks to the NPP operators at the same time. These risks are mainly due to the poor reliability of newly developed technology. KHNP's past experiences with the new equipment shows many cases of reliability problems. And their consequences include unintended plant trips, lowered acceptance of the new digital technology by the plant I and C maintenance crew, and increased licensing burden in answering for questions from the nuclear regulatory body. Considering the fact that the risk of these failures in the nuclear plant operation is far greater than those in other industry, nuclear power plant operators want proven technology for I and C systems. This paper presents an approach for the emulation of operational history through which a newly developed technology becomes a proven technology. One of the essential elements of this approach is the feedback scheme of running the new equipment in emulated environment, gathering equipment failure, and correcting the design(and test bed). The emulation of environment includes normal and abnormal events of the new equipment such as reconfiguration of control system due to power failure, plant operation including full spectrum of credible scenarios in an NPP. Emulation of I and C equipment execution mode includes normal operation, initialization and termination, abnormal operation, hardware maintenance and maintenance of algorithm/software. Plant specific simulator is used to create complete profile of plant operational conditions that I and C equipment is to experience in the real plant. Virtual operating crew technology is developed to run the simulator scenarios without involvement of actual operators

  1. Characteristics of low polymerization shrinkage flowable resin composites in newly-developed cavity base materials for bulk filling technique.

    Science.gov (United States)

    Nitta, Keiko; Nomoto, Rie; Tsubota, Yuji; Tsuchikawa, Masuji; Hayakawa, Tohru

    2017-11-29

    The purpose of this study was to evaluate polymerization shrinkage and other physical properties of newly-developed cavity base materials for bulk filling technique, with the brand name BULK BASE (BBS). Polymerization shrinkage was measured according to ISO/FDIS 17304. BBS showed the significantly lowest polymerization shrinkage and significantly higher depth of cure than conventional flowable resin composites (p<0.05). The Knoop hardness, flexural strength and elastic modulus of that were significantly lower than conventional flowable resin composites (p<0.05). BBS had the significantly greatest filler content (p<0.05). SEM images of the surface showed failure of fillers. The lowest polymerization shrinkage was due to the incorporation of a new type of low shrinkage monomer, which has urethane moieties. There were no clear correlations between inorganic filler contents and polymerization shrinkage, flexural strength and elastic modulus. In conclusion, the low polymerization shrinkage of BBS will be useful for cavity treatment in dental clinics.

  2. Recent developments in quantum field theory

    International Nuclear Information System (INIS)

    Ambjoern, J.; Petersen, J.L.; Durhuus, B.J.

    1985-01-01

    This is the second volume in a set of three containing the proceedings of 3 conferences held in Copenhagen, to mark the centennial of Niels Bohr. The purpose of this symposium was to bring together theoretical particle physicists to discuss the present status and, in particular, the latest developments in quantum field theory, in their broadest aspects. This volume contains the main 19 lectures and reflects the contemporary status of a line of development, one of whose initiators was Niels Bohr. (orig.)

  3. 14 CFR 26.39 - Newly produced airplanes: Fuel tank flammability.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Newly produced airplanes: Fuel tank... Tank Flammability § 26.39 Newly produced airplanes: Fuel tank flammability. (a) Applicability: This... Series 767 Series (b) Any fuel tank meeting all of the criteria stated in paragraphs (b)(1), (b)(2) and...

  4. Self-Esteem: A Comparison between Hong Kong Children and Newly Arrived Chinese Children

    Science.gov (United States)

    Chan, Yiu Man; Chan, Christine Mei-Sheung

    2004-01-01

    The Self-esteem Inventory developed by Coopersmith (1967) was used to measure the self-esteem of 387 Chinese children. The sample included newly arrived mainland Chinese children and Hong Kong children. The results showed significant statistical differences when measuring the self-esteem level associated with the length of their stay in Hong Kong…

  5. Chrysosplenium japonicum (Saxifragaceae, Newly Recorded from Taiwan

    Directory of Open Access Journals (Sweden)

    Tian-Chuan Hsu

    2011-11-01

    Full Text Available Chrysosplenium japonicum (Maxim. Makino (Saxifragaceae is newly recorded from northeastern Taiwan. Description, color photos and a key to the Chrysosplenium species in Taiwan are provided.

  6. Preliminary Phase Field Computational Model Development

    Energy Technology Data Exchange (ETDEWEB)

    Li, Yulan [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hu, Shenyang Y. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Xu, Ke [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Suter, Jonathan D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); McCloy, John S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Johnson, Bradley R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Ramuhalli, Pradeep [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2014-12-15

    This interim report presents progress towards the development of meso-scale models of magnetic behavior that incorporate microstructural information. Modeling magnetic signatures in irradiated materials with complex microstructures (such as structural steels) is a significant challenge. The complexity is addressed incrementally, using the monocrystalline Fe (i.e., ferrite) film as model systems to develop and validate initial models, followed by polycrystalline Fe films, and by more complicated and representative alloys. In addition, the modeling incrementally addresses inclusion of other major phases (e.g., martensite, austenite), minor magnetic phases (e.g., carbides, FeCr precipitates), and minor nonmagnetic phases (e.g., Cu precipitates, voids). The focus of the magnetic modeling is on phase-field models. The models are based on the numerical solution to the Landau-Lifshitz-Gilbert equation. From the computational standpoint, phase-field modeling allows the simulation of large enough systems that relevant defect structures and their effects on functional properties like magnetism can be simulated. To date, two phase-field models have been generated in support of this work. First, a bulk iron model with periodic boundary conditions was generated as a proof-of-concept to investigate major loop effects of single versus polycrystalline bulk iron and effects of single non-magnetic defects. More recently, to support the experimental program herein using iron thin films, a new model was generated that uses finite boundary conditions representing surfaces and edges. This model has provided key insights into the domain structures observed in magnetic force microscopy (MFM) measurements. Simulation results for single crystal thin-film iron indicate the feasibility of the model for determining magnetic domain wall thickness and mobility in an externally applied field. Because the phase-field model dimensions are limited relative to the size of most specimens used in

  7. Development of neutron calibration field using accelerators

    Energy Technology Data Exchange (ETDEWEB)

    Baba, Mamoru [Tohoku Univ., Cyclotron and Radioisotope Center, Sendai, Miyagi (Japan)

    2003-03-01

    A brief summary is given on the fast neutron calibration fields for 1) 8 keV to 15 MeV range, and 2) 30-80 MeV range. The field for 8 keV to 15 MeV range was developed at the Fast Neutron Laboratory (FNL) at Tohoku University using a 4.5 MV pulsed Dynamitron accelerator and neutron production reactions, {sup 45}Sc(p, n), {sup 7}Li(p, n), {sup 3}H(p, n), D(d, n) and T(d, n). The latter 30-80 MeV fields are setup at TIARA of Takasaki Establishment of Japan Atomic Energy Research Institute, and at Cyclotron Radio Isotope Center (CYRIC) of Tohoku University using a 90 MeV AVF cyclotron and the {sup 7}Li(p, n) reaction. These fields have been applied for various calibration of neutron spectrometers and dosimeters, and for irradiation purposes. (author)

  8. Magnetic fields in the solar system planets, moons and solar wind interactions

    CERN Document Server

    Wicht, Johannes; Gilder, Stuart; Holschneider, Matthias

    2018-01-01

    This book addresses and reviews many of the still little understood questions related to the processes underlying planetary magnetic fields and their interaction with the solar wind. With focus on research carried out within the German Priority Program ”PlanetMag”, it also provides an overview of the most recent research in the field. Magnetic fields play an important role in making a planet habitable by protecting the environment from the solar wind. Without the geomagnetic field, for example, life on Earth as we know it would not be possible. And results from recent space missions to Mars and Venus strongly indicate that planetary magnetic fields play a vital role in preventing atmospheric erosion by the solar wind. However, very little is known about the underlying interaction between the solar wind and a planet’s magnetic field. The book takes a synergistic interdisciplinary approach that combines newly developed tools for data acquisition and analysis, computer simulations of planetary interiors an...

  9. Time development of electric fields and currents in space plasmas

    Directory of Open Access Journals (Sweden)

    A. T. Y. Lui

    2006-05-01

    Full Text Available Two different approaches, referred to as Bu and Ej, can be used to examine the time development of electric fields and currents in space plasmas based on the fundamental laws of physics. From the Bu approach, the required equation involves the generalized Ohm's law with some simplifying assumptions. From the Ej approach, the required equation can be derived from the equation of particle motion, coupled self-consistently with Maxwell's equation, and the definition of electric current density. Recently, some strong statements against the Ej approach have been made. In this paper, we evaluate these statements by discussing (1 some limitations of the Bu approach in solving the time development of electric fields and currents, (2 the procedure in calculating self-consistently the time development of the electric current in space plasmas without taking the curl of the magnetic field in some cases, and (3 the dependency of the time development of magnetic field on electric current. It is concluded that the Ej approach can be useful to understand some magnetospheric problems. In particular, statements about the change of electric current are valid theoretical explanations of change in magnetic field during substorms.

  10. Fields of dreams[Oil field development in the Gulf of Mexico

    Energy Technology Data Exchange (ETDEWEB)

    DeLuca, Marshall

    2001-04-01

    The steady increase in deepwater development projects in the US Gulf of Mexico is discussed, and individual field descriptions are given with details of the development, the water depth, onstream date, and location for the Typhoon (Chevron), Prince (El Paso), Brutus (Shell), Nansen/Boomvang (Kerr-McGee), Canyon Express (TotalFinaElf), Medusa (Murphy), Horn Mountain (BP), NaKika (Shell), Crazy Horse (BP), Serrano/Oregano (Shell), and Crosby (Shell) projects. Information on the production, reserves, water depths and locations of >100 projects in the area are tabulated.

  11. People newly in love are more responsive to positive feedback.

    Science.gov (United States)

    Brown, Cassandra L; Beninger, Richard J

    2012-06-01

    Passionate love is associated with increased activity in dopamine-rich regions of the brain. Increased dopamine in these regions is associated with a greater tendency to learn from reward in trial-and-error learning tasks. This study examined the prediction that individuals who were newly in love would be better at responding to reward (positive feedback). In test trials, people who were newly in love selected positive outcomes significantly more often than their single (not in love) counterparts but were no better at the task overall. This suggests that people who are newly in love show a bias toward responding to positive feedback, which may reflect a general bias towards reward-seeking.

  12. Medium and Heavy Duty Vehicle Field Evaluations (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Walkowicz, K.

    2014-06-01

    This presentation discusses field evaluations of medium- and heavy-duty vehicles performed by NREL. The project provides medium-duty (MD) and heavy-duty (HD) test results, aggregated data, and detailed analysis, including 3rd party unbiased data (data that would not normally be shared by industry in an aggregated and detailed manner). Over 5.6 million miles of advanced technology MD and HD truck data have been collected, documented, and analyzed on over 240 different vehicles since 2002. Data, analysis, and reports are shared within DOE, national laboratory partners, and industry for R&D planning and strategy. The results help guide R&D for new technology development, help define intelligent usage of newly developed technology, and help fleets/users understand all aspects of advanced technology.

  13. Different patterns in the risk of newly developed fatty liver and lipid changes with tamoxifen versus aromatase inhibitors in postmenopausal women with early breast cancer: A propensity score-matched cohort study.

    Science.gov (United States)

    Hong, Namki; Yoon, Han Gyul; Seo, Da Hea; Park, Seho; Kim, Seung Il; Sohn, Joo Hyuk; Rhee, Yumie

    2017-09-01

    Management of metabolic complications of long-term adjuvant endocrine therapy in early breast cancer remained an unmet need. We aimed to compare the effects of tamoxifen (TMX) and aromatase inhibitors (AIs) on the risk of fatty liver in conjunction with longitudinal changes in the serum lipid parameters. Among 1203 subjects who were taking adjuvant TMX or AI (anastrozole or letrozole) without fatty liver at baseline, those taking TMX or AI were 1:1 matched on the propensity score. The primary outcome was newly developed fatty liver detected on annual liver ultrasonography. Among 328 matched subjects (mean age 53.5 years, body mass index 22.9 kg/m 2 ), 62 cases of fatty liver in the TMX group and 41 cases in the AI group were detected in a total of 987.4 person-years. The incidence rate of fatty liver was higher in the TMX group than in the AI group (128.7 versus 81.1 per 1000 person-years, P = 0.021), particularly within the first 2 years of therapy. TMX was associated with an increased 5-year risk of newly developed fatty liver (adjusted hazard ratio 1.61, P = 0.030) compared with AI independent of obesity and cholesterol level. Subjects who developed fatty liver had higher triglycerides (TGs) and lower high-density lipoprotein cholesterol (HDL-C) level at baseline than those without, which was sustained during follow-up despite the serum cholesterol-lowering effect of TMX. TMX independently increased the 5-year risk of newly developed fatty liver compared with AI in postmenopausal women with early breast cancer. Our findings suggest the need for considering the risk of fatty liver as a different adverse event profile between AI and TMX, particularly in patients with obesity, high TGs and low HDL-C. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. Improvement of the field homogeneity with a permanent magnet assembly for MRI

    International Nuclear Information System (INIS)

    Sakurai, H.; Aoki, M.; Miyamoto, T.

    1990-01-01

    In the last few years, MRI (Magnetic Resonance imaging) has become one of the most excellent and important radiological and diagnostic methods. For this application, a strong and uniform magnetic field is required in the area where the patient is examined. This requirement for a high order of homogeneity is increasing with the rapid progress of tomographic technology. On the other hand, the cost reduction for the magnet is also strongly required. As reported in the last paper, we developed and mass-produced a permanent type magnet using high energy Nd-Fe-B material. This paper presents a newly developed 15 plane measuring method instead of a 7 plane method to evaluate the homogeneous field precisely. By using this analytical method and linear programing method, a new-shaped pole piece has been developed. In consequence, homogeneity was improved twice as much and the magnet weight was reduced 10 % as compared with the formerly developed pole piece. (author)

  15. Wavelet-Based Quantum Field Theory

    Directory of Open Access Journals (Sweden)

    Mikhail V. Altaisky

    2007-11-01

    Full Text Available The Euclidean quantum field theory for the fields $phi_{Delta x}(x$, which depend on both the position $x$ and the resolution $Delta x$, constructed in SIGMA 2 (2006, 046, on the base of the continuous wavelet transform, is considered. The Feynman diagrams in such a theory become finite under the assumption there should be no scales in internal lines smaller than the minimal of scales of external lines. This regularisation agrees with the existing calculations of radiative corrections to the electron magnetic moment. The transition from the newly constructed theory to a standard Euclidean field theory is achieved by integration over the scale arguments.

  16. Workplace Violence and Job Outcomes of Newly Licensed Nurses

    OpenAIRE

    Chang, Hyoung Eun; Cho, Sung-Hyun

    2016-01-01

    Purpose: The purpose of this study was to examine the prevalence of workplace violence toward newly licensed nurses and the relationship between workplace violence and job outcomes. Methods: An online survey was conducted of newly licensed registered nurses who had obtained their license in 2012 or 2013 in South Korea and had been working for 5–12 months after first being employed. The sample consisted of 312 nurses working in hospitals or clinics. The Copenhagen Psychosocial Questionnaire...

  17. Electron-positron pair production in ultrastrong laser fields

    Directory of Open Access Journals (Sweden)

    Bai Song Xie

    2017-09-01

    Full Text Available Electron–positron pair production due to the decay of vacuum in ultrastrong laser fields is an interesting topic which is revived recently because of the rapid development of current laser technology. The theoretical and numerical research progress of this challenging topic is reviewed. Many new findings are presented by different approaches such as the worldline instantons, the S-matrix theory, the kinetic method by solving the quantum Vlasov equation or/and the real-time Dirac–Heisenberg–Wigner formalism, the computational quantum field theory by solving the Dirac equation and so on. In particular, the effects of electric field polarizations on pair production are unveiled with different patterns of created momentum spectra. The effects of polarizations on the number density of created particles and the nonperturbative signatures of multiphoton process are also presented. The competitive interplay between the multiphoton process and nonperturbation process plays a key role in these new findings. These newly discovered phenomena are valuable to deepen the understanding of pair production in complex fields and even have an implication to the study of strong-field ionization. More recent studies on the pair production in complex fields as well as beyond laser fields are briefly presented in the view point of perspective future.

  18. Investigation of various reconstruction parameters for algebraic reconstruction technique in a newly developed chest digital tomosynthesis

    International Nuclear Information System (INIS)

    Lee, H.; Choi, S.; Kim, Y.-S.; Park, H.-S.; Seo, C.-W.; Kim, H.-J.; Lee, D.; Lee, Y.

    2017-01-01

    Chest digital tomosynthesis (CDT) is a promising new modality that provides 3D information by reconstructing limited projection views. CDT systems have been developed to improve the limitations of conventional radiography such as image degradation and low sensitivity. However, the development of reconstruction methods is challenging because of the limited projection views within various angular ranges. Optimization of reconstruction parameters for various reconsturction methods in CDT system also is needed. The purpose of this study was to investigate the feasibility of algebraic reconstruction technique (ART) method, and to evaluate the effect of the reconstruction parameters for our newly developed CDT system. We designed ART method with 41 projection views over an angular range of ±20°. To investigate the effect of reconstruction parameters, we measured the contrast-to-noise ratio (CNR), artifact spread function (ASF), and quality factor (QF) using LUNGMAN phantom included tumors. We found that the proper choice of reconstruction parameters such as relaxation parameter, initial guess, and number of iterations improved the quality of reconstructed images from the same projection views. Optimal values of ART relaxation parameter with uniform (UI) and back-projection (BP) initial guesses were 0.4 and 0.6, respectively. BP initial guess improved image quality in comparison with UI initial guess, in terms of providing a higher CNR and QF values with a faster speed. CNR and QF values improved with increasing number of iteration. Particularly, ART method with BP initial guess (when β = 0.6) after 3-terations provide satisfactory reconstructed image. In conclusion, the use of ART method with proper reconstruction parameters provided better image quality than FBP method as well as conventional radiography. These results indicated that the ART method with optimal reconstruction parameters could improve image quality for nodule detection using the CDT system.

  19. Investigation of various reconstruction parameters for algebraic reconstruction technique in a newly developed chest digital tomosynthesis

    Science.gov (United States)

    Lee, H.; Choi, S.; Lee, D.; Kim, Y.-s.; Park, H.-S.; Lee, Y.; Seo, C.-W.; Kim, H.-J.

    2017-08-01

    Chest digital tomosynthesis (CDT) is a promising new modality that provides 3D information by reconstructing limited projection views. CDT systems have been developed to improve the limitations of conventional radiography such as image degradation and low sensitivity. However, the development of reconstruction methods is challenging because of the limited projection views within various angular ranges. Optimization of reconstruction parameters for various reconsturction methods in CDT system also is needed. The purpose of this study was to investigate the feasibility of algebraic reconstruction technique (ART) method, and to evaluate the effect of the reconstruction parameters for our newly developed CDT system. We designed ART method with 41 projection views over an angular range of ±20°. To investigate the effect of reconstruction parameters, we measured the contrast-to-noise ratio (CNR), artifact spread function (ASF), and quality factor (QF) using LUNGMAN phantom included tumors. We found that the proper choice of reconstruction parameters such as relaxation parameter, initial guess, and number of iterations improved the quality of reconstructed images from the same projection views. Optimal values of ART relaxation parameter with uniform (UI) and back-projection (BP) initial guesses were 0.4 and 0.6, respectively. BP initial guess improved image quality in comparison with UI initial guess, in terms of providing a higher CNR and QF values with a faster speed. CNR and QF values improved with increasing number of iteration. Particularly, ART method with BP initial guess (when β = 0.6) after 3-terations provide satisfactory reconstructed image. In conclusion, the use of ART method with proper reconstruction parameters provided better image quality than FBP method as well as conventional radiography. These results indicated that the ART method with optimal reconstruction parameters could improve image quality for nodule detection using the CDT system.

  20. A Phase I Dose Escalation Study of Hypofractionated IMRT Field-in-Field Boost for Newly Diagnosed Glioblastoma Multiforme

    Energy Technology Data Exchange (ETDEWEB)

    Monjazeb, Arta M., E-mail: arta.monjazeb@ucdmc.ucdavis.edu [U.C. Davis School of Medicine, Department of Radiation Oncology, Sacramento, CA (United States); Ayala, Deandra; Jensen, Courtney [Radiation Oncology, Wake Forest University Health Sciences, Winston-Salem, NC (United States); Case, L. Douglas [Biostatistical Sciences, Wake Forest University Health Sciences, Winston-Salem, NC (United States); Bourland, J. Daniel; Ellis, Thomas L. [Neurosurgery, Wake Forest University Health Sciences, Winston-Salem, NC (United States); McMullen, Kevin P.; Chan, Michael D. [Radiation Oncology, Wake Forest University Health Sciences, Winston-Salem, NC (United States); Tatter, Stephen B. [Neurosurgery, Wake Forest University Health Sciences, Winston-Salem, NC (United States); Lesser, Glen J. [Hematology Oncology, Wake Forest University Health Sciences, Winston-Salem, NC (United States); Shaw, Edward G. [Radiation Oncology, Wake Forest University Health Sciences, Winston-Salem, NC (United States)

    2012-02-01

    Objectives: To describe the results of a Phase I dose escalation trial for newly diagnosed glioblastoma multiforme (GBM) using a hypofractionated concurrent intensity-modulated radiotherapy (IMRT) boost. Methods: Twenty-one patients were enrolled between April 1999 and August 2003. Radiotherapy consisted of daily fractions of 1.8 Gy with a concurrent boost of 0.7 Gy (total 2.5 Gy daily) to a total dose of 70, 75, or 80 Gy. Concurrent chemotherapy was not permitted. Seven patients were enrolled at each dose and dose limiting toxicities were defined as irreversible Grade 3 or any Grade 4-5 acute neurotoxicity attributable to radiotherapy. Results: All patients experienced Grade 1 or 2 acute toxicities. Acutely, 8 patients experienced Grade 3 and 1 patient experienced Grade 3 and 4 toxicities. Of these, only two reversible cases of otitis media were attributable to radiotherapy. No dose-limiting toxicities were encountered. Only 2 patients experienced Grade 3 delayed toxicity and there was no delayed Grade 4 toxicity. Eleven patients requiring repeat resection or biopsy were found to have viable tumor and radiation changes with no cases of radionecrosis alone. Median overall and progression-free survival for this cohort were 13.6 and 6.5 months, respectively. One- and 2-year survival rates were 57% and 19%. At recurrence, 15 patients received chemotherapy, 9 underwent resection, and 5 received radiotherapy. Conclusions: Using a hypofractionated concurrent IMRT boost, we were able to safely treat patients to 80 Gy without any dose-limiting toxicity. Given that local failure still remains the predominant pattern for GBM patients, a trial of dose escalation with IMRT and temozolomide is warranted.

  1. A Phase I Dose Escalation Study of Hypofractionated IMRT Field-in-Field Boost for Newly Diagnosed Glioblastoma Multiforme

    International Nuclear Information System (INIS)

    Monjazeb, Arta M.; Ayala, Deandra; Jensen, Courtney; Case, L. Douglas; Bourland, J. Daniel; Ellis, Thomas L.; McMullen, Kevin P.; Chan, Michael D.; Tatter, Stephen B.; Lesser, Glen J.; Shaw, Edward G.

    2012-01-01

    Objectives: To describe the results of a Phase I dose escalation trial for newly diagnosed glioblastoma multiforme (GBM) using a hypofractionated concurrent intensity-modulated radiotherapy (IMRT) boost. Methods: Twenty-one patients were enrolled between April 1999 and August 2003. Radiotherapy consisted of daily fractions of 1.8 Gy with a concurrent boost of 0.7 Gy (total 2.5 Gy daily) to a total dose of 70, 75, or 80 Gy. Concurrent chemotherapy was not permitted. Seven patients were enrolled at each dose and dose limiting toxicities were defined as irreversible Grade 3 or any Grade 4–5 acute neurotoxicity attributable to radiotherapy. Results: All patients experienced Grade 1 or 2 acute toxicities. Acutely, 8 patients experienced Grade 3 and 1 patient experienced Grade 3 and 4 toxicities. Of these, only two reversible cases of otitis media were attributable to radiotherapy. No dose-limiting toxicities were encountered. Only 2 patients experienced Grade 3 delayed toxicity and there was no delayed Grade 4 toxicity. Eleven patients requiring repeat resection or biopsy were found to have viable tumor and radiation changes with no cases of radionecrosis alone. Median overall and progression-free survival for this cohort were 13.6 and 6.5 months, respectively. One- and 2-year survival rates were 57% and 19%. At recurrence, 15 patients received chemotherapy, 9 underwent resection, and 5 received radiotherapy. Conclusions: Using a hypofractionated concurrent IMRT boost, we were able to safely treat patients to 80 Gy without any dose-limiting toxicity. Given that local failure still remains the predominant pattern for GBM patients, a trial of dose escalation with IMRT and temozolomide is warranted.

  2. Assessment of salt tolerance of some newly developed and candidate wheat (triticum aestivum l.) cultivars using gas exchange and chlorophyll fluorescence attributes

    International Nuclear Information System (INIS)

    Kanwal, H.; Shahbaz, M.; Ashraf, M.

    2011-01-01

    The present study was aimed to assess salt tolerance of some newly developed and candidate cultivars of wheat using gas exchange and chlorophyll fluorescence parameters. Ten wheat cultivars including five newly developed (S-24, Saher-2006, Fsd-2008, Lasani and Inqlab-91) and five candidate (P .B-18, M.P-65, S.H-20, AARI-10 and G.A-20) were grown in sand culture. Salt stress (150 mM NaCl in Hoagland's nutrient solution) was applied at the seedling stage. A significant reduction in plant biomass production was recorded in all wheat cultivars. Cultivars S-24, Saher-2006 and Fsd-2008 showed less reduction in biomass production as compared with the other cultivars. Different gas exchange attributes such as leaf net photosynthetic rate (A), transpiration rate ( E), and stomatal conductance (gs) were also adversely affected due to salt stress and were positively associated with the plant biomass production of the genotypes under saline stress. More negative effects in relation to these gas exchange attributes were recorded in cvs. Lasani, G.A-20 and ARRI-10 than those in the other cultivars. Leaf maximum chlorophyll fluorescence (Fm), maximum fluorescence at steady state (Fms ), and photochemical fluorescence quenching (Qp) increased while maximum quantum yield (Fv/Fm), quantum yield of electron transport (Qp), electron transport rate ( ETR ) and non-photochemical quenching (Qn) decreased due to imposition of salt stress. The adverse effects of salt stress on these chlorophyll fluorescence attributes were minimum in cultivars S-24, Saher-2006 and Fsd-2008. A significant positive correlation was recorded between biomass production, different gas exchange attributes and chlorophyll fluorescence parameters. Overall, cvs. S-24, Saher-2006 and Fsd-2008 were ranked as salt tolerant on the basis of their performance in biomass production, gas exchange attributes and chlorophyll fluorescence parameters. (author)

  3. Kalimantan field development hikes gas supply for LNG export

    International Nuclear Information System (INIS)

    Suharmoko, G.R.

    1991-01-01

    This paper reports on the development of Tambora and Tunu gas fields in Kalimantan that have increased available gas supply for the export of liquefied natural gas (LNG) from Indonesia. The demand for LNG is increasing in the energy thirsty Far East market. And Indonesia, the world's largest exporter, is keeping pace by expanding the Bontang liquefaction plant in East Kalimantan. A fifth train, with a capacity of around 2.5 million tons/year, began operating in January 1990. Start-up of a sixth train, of identical capacity, is planned for January 1994. The Bontang plant is operated by PT Badak on behalf of Pertamina, the Indonesian state oil and gas mining company. The feed to the fifth train comes primarily from the first-phase development of Total Indonesie's two gas fields, Tambora and Tunu. The sixth train will be fed by a second-phase development of the Tunu field

  4. Endogenous electric fields in embryos during development, regeneration and wound healing

    International Nuclear Information System (INIS)

    Nuccitelli, R.

    2003-01-01

    All embryos that have been investigated drive ionic currents through themselves and these currents will generate internal electric fields. Here, those examples in which such fields have been measured directly are discussed. The first such measurements were made in chick embryos and about 20 mV mm -1 was measured near the posterier intestinal portal in 2-4-day-old embryos. This electric field is important for the development of tail structures because reducing its magnitude results in abnormal tail development. The second embryonic electric field measured directly was in the axolotl, where a rostral-caudal field of about the same magnitude was detected. Modification of this field during neurulation but not gastrulation caused developmental abnormalities. Most recently, the development of left-right asymmetry in frog and chick embryos was found to require a voltage difference between blastomeres at a very early developmental stage. This field was measured in the chick embryo to be 10-20 mV mm -1 across the primitive streak. Mammalian skin wounds generate 150 mV mm -1 fields lateral to the wound and corneal epidermal wounds exhibit lateral fields of 40 mV mm -1 . The presence of these endogenous fields would suggest that exposures to external electric fields should be limited to magnitudes of less than 0.1 V m -1 . (author)

  5. Endogenous electric fields in embryos during development, regeneration and wound healing

    Energy Technology Data Exchange (ETDEWEB)

    Nuccitelli, R

    2003-07-01

    All embryos that have been investigated drive ionic currents through themselves and these currents will generate internal electric fields. Here, those examples in which such fields have been measured directly are discussed. The first such measurements were made in chick embryos and about 20 mV mm-1 was measured near the posterier intestinal portal in 2-4-day-old embryos. This electric field is important for the development of tail structures because reducing its magnitude results in abnormal tail development. The second embryonic electric field measured directly was in the axolotl, where a rostral-caudal field of about the same magnitude was detected. Modification of this field during neurulation but not gastrulation caused developmental abnormalities. Most recently, the development of left-right asymmetry in frog and chick embryos was found to require a voltage difference between blastomeres at a very early developmental stage. This field was measured in the chick embryo to be 10-20 mV mm-1 across the primitive streak. Mammalian skin wounds generate 150 mV mm-1 fields lateral to the wound and corneal epidermal wounds exhibit lateral fields of 40 mV mm-1. The presence of these endogenous fields would suggest that exposures to external electric fields should be limited to magnitudes of less than 0.1 V m-1. (author)

  6. The role of infections and coinfections with newly identified and emerging respiratory viruses in children

    Directory of Open Access Journals (Sweden)

    Debiaggi Maurizia

    2012-10-01

    Full Text Available Abstract Acute respiratory infections are a major cause of morbidity in children both in developed and developing countries. A wide range of respiratory viruses, including respiratory syncytial virus (RSV, influenza A and B viruses, parainfluenza viruses (PIVs, adenovirus, rhinovirus (HRV, have repeatedly been detected in acute lower respiratory tract infections (LRTI in children in the past decades. However, in the last ten years thanks to progress in molecular technologies, newly discovered viruses have been identified including human Metapneumovirus (hMPV, coronaviruses NL63 (HcoV-NL63 and HKU1 (HcoV-HKU1, human Bocavirus (HBoV, new enterovirus (HEV, parechovirus (HpeV and rhinovirus (HRV strains, polyomaviruses WU (WUPyV and KI (KIPyV and the pandemic H1N1v influenza A virus. These discoveries have heavily modified previous knowledge on respiratory infections mainly highlighting that pediatric population is exposed to a variety of viruses with similar seasonal patterns. In this context establishing a causal link between a newly identified virus and the disease as well as an association between mixed infections and an increase in disease severity can be challenging. This review will present an overview of newly recognized as well as the main emerging respiratory viruses and seek to focus on the their contribution to infection and co-infection in LRTIs in childhood.

  7. Exploring Content Validity of Shore Handwriting Screening and Newly Developed Score Sheet With Pre-Kindergarten Students

    Directory of Open Access Journals (Sweden)

    Denise K. Donica

    2015-07-01

    Full Text Available Background: Limited tools exist to measure handwriting readiness skills of pre-kindergarten students. This study was a preliminary exploration of content validity of the Shore Handwriting Screening (SHS and the newly developed Score Sheet with the Bruininks-Oseretsky Test of Motor Proficiency, Second Edition (BOT-2 in 4- and 5-year-old pre-kindergarten students. Because socioeconomic status (SES is known to impact handwriting skills, data from two different socioeconomic groups were collected. Method: Students from a Lower SES group (n = 36 and a Higher SES group (n = 14 completed the SHS and fine motor composite of the BOT-2. Pearson’s correlation was used to compare scores on the two assessments within the two groups. Results: SHS overall percentage scores were compared to standard scores and composite scores of the BOT-2. SHS scores displayed moderate to high correlation with fine manual control portions of the BOT-2 for the Lower SES group and low to moderate correlation for the same portion in the Higher SES group. Conclusion: SHS and the Score Sheet correlate to fine and visual-motor skill subtests on the fine manual control portions of the BOT-2, which supports the need for further research on the reliability and validity of the Score Sheet for use in practice.

  8. Informal meeting on recent developments in field theory

    International Nuclear Information System (INIS)

    Anon.

    1977-12-01

    A topical meeting on recent developments in field theory was organized by the International Centre for Theoretical Physics from 21 to 23 November 1977. The publication is a compilation of the abstracts of lecture given. The mayor themes of the meeting were the problem of confinement, the quantization of Yang-Mills theories and the topological aspects of field theories in flat and curved spaces

  9. Development case histories: Tongonan and Palinpinon geothermal fields, Philippines

    International Nuclear Information System (INIS)

    Ogena, M.S.

    1992-01-01

    The background on the general scenario of energy resource development in the country is described. Highlights of the exploration history of the Tongonan and Palinpinon geothermal fields in the Philippines are then presented. This is discussed in conjunction with the strategies and policies taken in the development of each field. Finally, the common policies and contrasting development strategies are compared and evaluated. The conclusion derived is that the development strategy decisions at Tongonan are influenced by the regional power demand, topography, and the large extent of the resource. In contrast, the development at Palinpinon is less constrained by the external influence of regional power needs, but, instead, is significantly dominated by the limitations imposed by the rugged terrain and the physical characteristics of the resource area. Such comparison demonstrates the site-specific nature of geothermal development. (auth.). 8 figs.; 2 refs

  10. Exercise recommendations in patients with newly diagnosed fibromyalgia.

    Science.gov (United States)

    Wilson, Brad; Spencer, Horace; Kortebein, Patrick

    2012-04-01

    To evaluate exercise recommendations in patients newly diagnosed with fibromyalgia. A retrospective chart review. A public university rheumatology clinic. Patients newly diagnosed with fibromyalgia (N = 122). Frequency and type of exercise recommendations. The mean (standard deviation) age of these patients with fibromyalgia was 45 ± 12 years; 91% were women. Exercise was recommended as part of the documented treatment plan in 47% of these patients (57/122); only 3 patients had a documented contraindication for exercise. Aquatic exercise was most frequently recommended (56% [32/57]), followed by combined aquatic-aerobic exercise (26% [15/57]), and, infrequently, aerobic exercise only (5% [3/57]); only 7% of these patients (4/57) were referred for physical therapy. The primary method of communication was verbal discussion (94% [54/57]). Although there is well-documented evidence that exercise is beneficial for patients with fibromyalgia, we found that less than half of patients with newly diagnosed fibromyalgia in our study were provided recommendations to initiate an exercise program as part of their treatment plan. Further investigation of these findings are warranted, including evaluation of other university and community rheumatology practices as well as that of other physicians caring for patients with fibromyalgia. However, our findings indicate that there appears to be an opportunity to provide more specific and practical education regarding the implementation of an exercise regimen for patients with newly diagnosed fibromyalgia. Physiatrists may be particularly well suited to manage the exercise component of patients with fibromyalgia because of their specialized training in exercise prescription. Copyright © 2012 American Academy of Physical Medicine and Rehabilitation. Published by Elsevier Inc. All rights reserved.

  11. Educating Future Leaders of the Sport-Based Youth Development Field

    Science.gov (United States)

    Whitley, Meredith A.; McGarry, Jennifer Bruening; Martinek, Thomas; Mercier, Kevin; Quinlan, Melissa

    2017-01-01

    In recent years, a substantial surge has occurred in the number of initiatives, events and organizations focused on using sport as a tool for development, peacebuilding and humanitarian efforts. This has created a growing need for educated leaders in the sport-based youth development field as the job market in this field continues to expand. The…

  12. Critical thinking dispositions among newly graduated nurses.

    Science.gov (United States)

    Wangensteen, Sigrid; Johansson, Inger S; Björkström, Monica E; Nordström, Gun

    2010-10-01

    The aim of the study was to describe critical thinking dispositions among newly graduated nurses in Norway, and to study whether background data had any impact on critical thinking dispositions. Competence in critical thinking is one of the expectations of nursing education. Critical thinkers are described as well-informed, inquisitive, open-minded and orderly in complex matters. Critical thinking competence has thus been designated as an outcome for judging the quality of nursing education programmes and for the development of clinical judgement. The ability to think critically is also described as reducing the research-practice gap and fostering evidence-based nursing. A cross-sectional descriptive study was performed. The data were collected between October 2006 and April 2007 using the California Critical Thinking Disposition Inventory. The response rate was 33% (n = 618). Pearson's chi-square tests were used to analyse the data. Nearly 80% of the respondents reported a positive disposition towards critical thinking. The highest mean score was on the Inquisitiveness subscale and the lowest on the Truth-seeking subscale. A statistically significant higher proportion of nurses with high critical thinking scores were found among those older than 30 years, those with university education prior to nursing education, and those working in community health care. Nurse leaders and nurse teachers should encourage and nurture critical thinking among newly graduated nurses and nursing students. The low Truth-seeking scores found may be a result of traditional teaching strategies in nursing education and might indicate a need for more student-active learning models. © 2010 The Authors. Journal of Advanced Nursing © 2010 Blackwell Publishing Ltd.

  13. The ecological and construct validity of a newly developed measure of executive function: the Virtual Library Task.

    Science.gov (United States)

    Renison, Belinda; Ponsford, Jennie; Testa, Renee; Richardson, Barry; Brownfield, Kylie

    2012-05-01

    Virtual reality (VR) assessment paradigms have the potential to address the limited ecological validity of pen and paper measures of executive function (EF) and the pragmatic and reliability issues associated with functional measures. To investigate the ecological validity and construct validity of a newly developed VR measure of EF, the Virtual Library Task (VLT); a real life analogous task--the Real Library Task (RLT); and five neuropsychological measures of EF were administered to 30 patients with traumatic brain injury (TBI) and 30 healthy Controls. Significant others for each participant also completed the Dysexecutive Questionnaire (DEX), which is a behavioral rating scale of everyday EF. Performances on the VLT and the RLT were significantly positively correlated indicating that VR performance is similar to real world performance. The TBI group performed significantly worse than the Control group on the VLT and the Modified Six Elements Test (MSET) but the other four neuropsychological measures of EF failed to differentiate the groups. Both the MSET and the VLT significantly predicted everyday EF suggesting that they are both ecologically valid tools for the assessment of EF. The VLT has the advantage over the MSET of providing objective measurement of individual components of EF.

  14. Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia

    DEFF Research Database (Denmark)

    Saglio, Giuseppe; Kim, Dong-Wook; Issaragrisil, Surapol

    2010-01-01

    Nilotinib has been shown to be a more potent inhibitor of BCR-ABL than imatinib. We evaluated the efficacy and safety of nilotinib, as compared with imatinib, in patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia (CML) in the chronic phase.......Nilotinib has been shown to be a more potent inhibitor of BCR-ABL than imatinib. We evaluated the efficacy and safety of nilotinib, as compared with imatinib, in patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia (CML) in the chronic phase....

  15. Transformation of organic N newly added to red soil treated with different cultural practices

    Institute of Scientific and Technical Information of China (English)

    ZhangQin-Zheng; YeQing-Fu; 等

    1998-01-01

    By using 15N tracer method,transformation of organic N,which wqas newly added to red soil treated with different cultural practices,was studied under thelaboratory incubation condition.The experimental results showed that the transformation of N from newly added organic matter and soil native pool during incubation was influenced by cultural practice treatment beforeincubation.Fallow was favorable to the mineralization of newly added organic N and soil N compared with the planting wheat treatment.Planting wheat greatly increased the loss of soil N.Application of fertilizers stimulated the mineralization of newly added organic N and application of organic matter reduced the mineralization,but stimulated microbialtransformation of newly adde4d organic N.

  16. UCSD SORT Test (U-SORT): Examination of a newly developed organizational skills assessment tool for severely mentally ill adults.

    Science.gov (United States)

    Tiznado, Denisse; Mausbach, Brent T; Cardenas, Veronica; Jeste, Dilip V; Patterson, Thomas L

    2010-12-01

    The present investigation examined the validity of a new cognitive test intended to assess organizational skills. Participants were 180 middle-aged or older participants with a Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition diagnosis of schizophrenia or schizoaffective disorder. Participants' organizational skills were measured using our newly developed University of California, San Diego Sorting Test (U-SORT), a performance-based test of organizational ability in which subjects sort objects (e.g., battery, pens) from a "junk drawer" into "keep" versus "trash" piles. Significant correlations between U-SORT scores and theoretically similar constructs (i.e. functional capacity, cognitive functioning, and clinical symptoms) were acceptable (mean r = 0.34), and weak correlations were found between U-SORT scores and theoretically dissimilar constructs (e.g., health symptoms, social support, gender; mean r = 0.06 ). The correlation between assessment scores provides preliminary support for the U-SORT test as a brief, easily transportable, reliable, and valid measure of functioning for this population.

  17. Development of a one-step RT-PCR assay for detection of pancoronaviruses (α-, β-, γ-, and δ-coronaviruses) using newly designed degenerate primers for porcine and avian `fecal samples.

    Science.gov (United States)

    Hu, Hui; Jung, Kwonil; Wang, Qiuhong; Saif, Linda J; Vlasova, Anastasia N

    2018-06-01

    Coronaviruses (CoVs) are critical human and animal pathogens because of their potential to cause severe epidemics of respiratory or enteric diseases. In pigs, the newly emerged porcine deltacoronavirus (PDCoV) and re-emerged porcine epidemic diarrhea virus (PEDV) reported in the US and Asia, as well as the discovery of novel CoVs in wild bats or birds, has necessitated development of improved detection and control measures for these CoVs. Because the previous pancoronavirus (panCoV) RT-PCR established in our laboratory in 2007-2011 did not detect deltacoronaviruses (δ-CoVs) in swine fecal and serum samples, our goal was to develop a new panCoV RT-PCR assay to detect known human and animal CoVs, including δ-CoVs. In this study, we designed a new primer set to amplify a 668 bp-region within the RNA-dependent RNA polymerase (RdRP) gene that encodes the most conserved protein domain of α-, β-, γ-, and δ-CoVs. We established a one-step panCoV RT-PCR assay and standardized the assay conditions. The newly established panCoV RT-PCR assay was demonstrated to have a high sensitivity and specificity. Using a panel of 60 swine biological samples (feces, intestinal contents, and sera) characterized by PEDV, PDCoV and transmissible gastroenteritis virus-specific RT-PCR assays, we demonstrated that sensitivity and specificity of the newly established panCoV RT-PCR assay were 100%. 400 avian fecal (RNA) samples were further tested simultaneously for CoV by the new panCoV RT-PCR and a one-step RT-PCR assay with the δ-CoV nucleocapsid-specific universal primers. Four of 400 avian samples were positive for CoV, three of which were positive for δ-CoV by the conventional RT-PCR. PanCoV RT-PCR fragments for 3 of the 4 CoVs were sequenced. Phylogenetic analysis revealed the presence of one γ-CoV and two δ-CoV in the sequenced samples. The newly designed panCoV RT-PCR assay should be useful for the detection of currently known CoVs in animal biological samples. Copyright © 2018

  18. Wide-field Infrared Survey Explorer Observations of the Evolution of Massive Star-forming Regions

    OpenAIRE

    Koenig, X. P.; Leisawitz, D. T.; Benford, D. J.; Rebull, L. M.; Padgett, D. L.; Assef, R. J.

    2012-01-01

    We present the results of a mid-infrared survey of 11 outer Galaxy massive star-forming regions and 3 open clusters with data from the Wide-field Infrared Survey Explorer (WISE). Using a newly developed photometric scheme to identify young stellar objects and exclude extragalactic contamination, we have studied the distribution of young stars within each region. These data tend to support the hypothesis that latter generations may be triggered by the interaction of winds and radiation from th...

  19. Coping strategies among patients with newly diagnosed amyotrophic lateral sclerosis.

    Science.gov (United States)

    Jakobsson Larsson, Birgitta; Nordin, Karin; Askmark, Håkan; Nygren, Ingela

    2014-11-01

    To prospectively identify different coping strategies among newly diagnosed amyotrophic lateral sclerosis patients and whether they change over time and to determine whether physical function, psychological well-being, age and gender correlated with the use of different coping strategies. Amyotrophic lateral sclerosis is a fatal disease with impact on both physical function and psychological well-being. Different coping strategies are used to manage symptoms and disease progression, but knowledge about coping in newly diagnosed amyotrophic lateral sclerosis patients is scarce. This was a prospective study with a longitudinal and descriptive design. A total of 33 patients were included and evaluation was made at two time points, one to three months and six months after diagnosis. Patients were asked to complete the Motor Neuron Disease Coping Scale and the Hospital Anxiety and Depression Scale. Physical function was estimated using the revised Amyotrophic Lateral Sclerosis Functional Rating Scale. The most commonly used strategies were support and independence. Avoidance/venting and information seeking were seldom used at both time points. The use of information seeking decreased between the two time points. Men did not differ from women, but patients ≤64 years used positive action more often than older patients. Amyotrophic Lateral Sclerosis Functional Rating Scale was positively correlated with positive action at time point 1, but not at time point 2. Patients' psychological well-being was correlated with the use of different coping strategies. Support and independence were the most used coping strategies, and the use of different strategies changed over time. Psychological well-being was correlated with different coping strategies in newly diagnosed amyotrophic lateral sclerosis patients. The knowledge about coping strategies in early stage of the disease may help the nurses to improve and develop the care and support for these patients. © 2014 John Wiley

  20. MUSE integral-field spectroscopy towards the Frontier Fields Cluster Abell S1063

    DEFF Research Database (Denmark)

    Karman, W.; Caputi, K. I.; Grillo, C.

    2015-01-01

    We present the first observations of the Frontier Fields Cluster Abell S1063 taken with the newly commissioned Multi Unit Spectroscopic Explorer (MUSE) integral field spectrograph. Because of the relatively large field of view (1 arcmin^2), MUSE is ideal to simultaneously target multiple galaxies...... the cluster, we find 17 galaxies at higher redshift, including three previously unknown Lyman-alpha emitters at z>3, and five multiply-lensed galaxies. We report the detection of a new z=4.113 multiply lensed galaxy, with images that are consistent with lensing model predictions derived for the Frontier...... of scientific topics that can be addressed with a single MUSE pointing. We conclude that MUSE is a very efficient instrument to observe galaxy clusters, enabling their mass modelling, and to perform a blind search for high-redshift galaxies....

  1. Effect of mulching systems on fruit quality and phytochemical composition of newly developed strawberry lines

    Directory of Open Access Journals (Sweden)

    Li Fan

    2012-06-01

    Full Text Available The effects of three mulching systems on total yield, average yield per plant, average fruit weight, soluble solids content (SSC, titratable acidity (TA, firmness and oxygen radical absorbance capacity (ORAC of two newly developed lines (‘Orléans’ and ‘Saint Pierre’, one advanced selection (‘SJ8976-1’ and two commonly used cultivars (‘Jewel’ and ‘Kent’ were evaluated. The studied mulching systems were: plastic mulch (PM, mulch with row cover (PMRC, and matted-row system (MRS. Results showed that plastic mulch with row cover (PMRC generally increased yield per plant, average fruit weight, SSC, firmness and ORAC, but differences varied within harvest times. No significant differences in total yield and TA were observed under the selected mulching systems. Both PMRC and PM accelerated the harvest periods compared to MRS. ‘Kent’ and ‘Jewel’ had the highest total yield while ‘SJ8976-1’ and ‘St-Pierre’ had the highest average fruit weight. The highest SSC, TA and ORAC were found in ‘Jewel’. There was no interaction between the mulching systems and genotypes, indicating that the effect of production system is independent of cultivars. PMRC seems to be a better growing system, improving fruit quality and increasing the nutritional value of all genotypes. By allowing off-season fruit production in cool climates, PMRC can be an alternative method to the costly high tunnels.

  2. Field development. Concept selection in deep water environment offshore Angola

    Energy Technology Data Exchange (ETDEWEB)

    Guenot, A.; Berger, J.C.; Limet, N. [TotalFinaElf, la Defense 6, Rosa-Lirio Project Group, 92 - Courbevoie (France)

    2002-10-01

    The significant oil discoveries made at the end of the 90's in the deep water environment offshore the coast of Angola, has led to a considerable amount of development activities. The first field in production was the turnkey development of the Kuito field on the Block 14 operated by Chevron. More recently the Girassol field has been put successfully in production on the Block 17, operated by TotalFinaElf. Both developments are making use of sub-sea wells connected to a moored dedicated FPSO. On the western side of the Girassol field, several discoveries have been made. They are known as the Rosa Lirio pole, from the names of two of the main channels. Values for water depth are in the same range than on Girassol (1300- 1400 m). A project group has been established in 1999 to evaluate the development of these discoveries. The purpose of this paper is to present the conceptual work which as been carried out, and in particular to show that even if many different concepts have been evaluated, the final choice has been also to make use of sub-sea trees. (authors)

  3. Economic strategies to maximize profits from satellite field developments

    International Nuclear Information System (INIS)

    Antia, D.D.J.

    1994-01-01

    The main strategies that can be used to maximize profits from integrated satellite field developments are: (1) restructuring the cost, production and revenue profile of the satellite field; and (2) increasing the volume of oil/gas processed, and available for future use, by the central processing and distribution facility through: (a) using a combined strategy of low tariffs, volume discount, and netback agreements; (b) using reusable facilities, shared facilities, extended reach wells, contractor finance, partnering agreements, netback agreements, oil/gas price swaps; and (c) improving development, discovery and exploration efficiency

  4. Application of newly developed Fluoro-QC software for image quality evaluation in cardiac X-ray systems.

    Science.gov (United States)

    Oliveira, M; Lopez, G; Geambastiani, P; Ubeda, C

    2018-05-01

    A quality assurance (QA) program is a valuable tool for the continuous production of optimal quality images. The aim of this paper is to assess a newly developed automatic computer software for image quality (IR) evaluation in fluoroscopy X-ray systems. Test object images were acquired using one fluoroscopy system, Siemens Axiom Artis model (Siemens AG, Medical Solutions Erlangen, Germany). The software was developed as an ImageJ plugin. Two image quality parameters were assessed: high-contrast spatial resolution (HCSR) and signal-to-noise ratio (SNR). The time between manual and automatic image quality assessment procedures were compared. The paired t-test was used to assess the data. p Values of less than 0.05 were considered significant. The Fluoro-QC software generated faster IQ evaluation results (mean = 0.31 ± 0.08 min) than manual procedure (mean = 4.68 ± 0.09 min). The mean difference between techniques was 4.36 min. Discrepancies were identified in the region of interest (ROI) areas drawn manually with evidence of user dependence. The new software presented the results of two tests (HCSR = 3.06, SNR = 5.17) and also collected information from the DICOM header. Significant differences were not identified between manual and automatic measures of SNR (p value = 0.22) and HCRS (p value = 0.46). The Fluoro-QC software is a feasible, fast and free to use method for evaluating imaging quality parameters on fluoroscopy systems. Copyright © 2017 The College of Radiographers. Published by Elsevier Ltd. All rights reserved.

  5. Possible origin of Saturn's newly discovered outer ring

    International Nuclear Information System (INIS)

    Moehlmann, D.

    1986-01-01

    Within a planetogonic model the self-gravitationally caused formation of pre-planetary and pre-satellite rings from an earlier thin disk is reported. The theoretically derived orbital radii of these rings are compared with the orbital levels in the planetary system and the satellite systems of Jupiter, Saturn and Uranus. From this comparison it is concluded that at the radial position of Saturn's newly discovered outer ring an early pre-satellite ring of more or less evolved satellites could have existed. These satellites should have been disturbed in their evolution by the gravitation of the neighbouring massive satellite Titan. The comparison also may indicate similarities between the asteroidal belt and the newly discovered outer ring of Saturn

  6. Oral Cancer Knowledge Assessment: Newly Graduated versus Senior Dental Clinicians

    Science.gov (United States)

    Salgado de Souza, Ricardo; Gallego Arias Pecorari, Vanessa; Lauria Dib, Luciano

    2018-01-01

    The present study assessed the level of dentists' knowledge regarding oral cancer in the city of São Paulo, Brazil. A questionnaire was used to compare the level of knowledge among newly graduated and senior clinicians. A total of 20,154 e-mails were correctly delivered to the dentists registered in the database of the Regional Dentistry Council of São Paulo, and 477 (2.36%) responses were received. This sample consisted of 84 newly graduated clinicians and 105 senior clinicians. For the statistical analysis, the chi-square test and the logistic regression analysis were performed with α = 0.05, and the results were described herein. According to their knowledge level, the results were statistically different between the groups, since 19% of the newly graduated clinicians were evaluated with knowledge grade A (excellent) in comparison to 6.7% of the senior clinicians. In spite of the results indicated that newly graduated clinicians' knowledge regarding oral cancer was 2.1 times higher, 34.5% of the professionals in this group had regular or poor knowledge on the subject, and several questions relating to clinical characteristics and risk factors indicated that there still exist some knowledge gaps, demonstrating that there is a need for further studies and information activities addressing oral cancer. PMID:29666649

  7. Quantification of Fusarium oxysporum in fumigated soils by a newly developed real-time PCR assay to assess the efficacy of fumigants for Fusarium wilt disease in strawberry plants.

    Science.gov (United States)

    Li, Yuan; Mao, Liangang; Yan, Dongdong; Ma, Taotao; Shen, Jin; Guo, Meixia; Wang, Qiuxia; Ouyang, Canbin; Cao, Aocheng

    2014-11-01

    Two soil fumigants, chloropicrin (CP) and dimethyl disulfide (DMDS), were used to control Fusarium wilt disease (FWD) which caused large economic losses in strawberries. The fumigants were evaluated alone and in combination in a laboratory study and in strawberry greenhouses. Laboratory tests found that combinations of CP and DMDS indicated a positive synergistic activity on Fusarium oxysporum. A newly developed quantitative assay for F. oxysporum involving real-time PCR was used successfully to evaluate F. oxysporum control by the fumigants; it provided similar results to the selective medium but was less time-consuming and less labor intensive. Greenhouse trials revealed that the combination of CP and DMDS successfully suppressed the incidence of FWD and sharply reduced the population density of F. oxysporum, which significantly increased fruit branch number and maintained a good strawberry yield, higher than methyl bromide (MB) treatment. All of the treatments provided significantly better results than the non-treated control. This study confirms that the newly developed real-time PCR quantitative assay for F. oxysporum was suitable for the control efficacy evaluation of soil fumigants and that the novel fumigant combination of CP and DMDS offers a promising effective alternative to MB for the control of F. oxysporum in strawberry greenhouses. © 2013 Society of Chemical Industry.

  8. Development of broomcorn varieties at Institute of Field and Vegetable Crops Novi Sad

    Directory of Open Access Journals (Sweden)

    Sikora Vladimir

    2010-01-01

    Full Text Available Broomcorn breeding program at Institute of Field and Vegetable Crops Novi Sad has been in continuation since 1952. According to the demand of broomcorn and broom producers, in several cycles during this period, five generations of breeders have exploited wealthy genetic collection and created 11 broomcorn cultivars. In the beginning, the primary target was creation of European dwarf type cultivars. This phase has resulted in three cultivars 'Bački biser', 'Neoplanta' and 'Panonija'. Next phase, which was crowned with cultivars 'Sava', 'Tisa', 'Jumak' and 'Jantar', was focused on higher yield and better quality of broomcorn brushes. Contemporary cultivars 'Reform' and 'Neoplanta plus' which preserve good agro-technological traits of former cultivars, are selected to early maturity and fiber fineness. Selection of new cultivars 'Tan Sava' and 'No. 5' was concentrated on elimination of red coloration of panicles and even earlier maturity. Newly selected inbred lines tolerant to plant diseases and with positive panicle exertion are presently tested as parental lines in experimental hybrids. .

  9. Career Motivation in Newly Licensed Registered Nurses: What Makes Them Remain

    Science.gov (United States)

    Banks, Zarata Mann; Bailey, Jessica H.

    2010-01-01

    Despite vast research on newly licensed registered nurses (RNs), we don't know why some newly licensed registered nurses remain in their current jobs and others leave the nursing profession early in their career. Job satisfaction, the most significant factor emerging from the literature, plays a significant role in nurses' decisions to remain in…

  10. PREVALENCE OF DIABETIC RETINOPATHY IN PATIENTS WITH NEWLY DIAGNOSED TYPE II DIABETES MELLITUS

    Directory of Open Access Journals (Sweden)

    A. Bostak

    2006-11-01

    Full Text Available Diabetic retinopathy is a common complication of type II diabetes mellitus and carries with it the threat of blindness. Accurate information regarding the incidence of diabetic retinopathy and associated risk factors is important in the prevention of its development and of the visual impairment caused by this complication. This study was designed to determine the prevalence of diabetic retinopathy in newly diagnosed patients with type II diabetes mellitus. We have also evaluated the association of diabetic retinopathy with clinical and biochemical variables. In a cross-sectional study, 152 consecutive patients with newly diagnosed type II diabetes mellitus were referred from two outpatient clinics in Tehran for ophthalmologic exam to detect retinopathy. Indirect ophthalmoscopy was performed and data regarding risk factors were extracted from routine medical records. Chi square and Mann Whitney U tests were used to analyze the data. The overall prevalence of diabetic retinopathy was 13.8 %( 21 cases: three cases with microaneurysm only, 10 with mild, 5 with moderate and 2 with severe non proliferative diabetic retinopathy. Only one patient had advanced proliferative retinopathy. The prevalence of diabetic retinopathy was positively associated with age, duration of disease, fasting plasma glucose, HbA1c, and systolic blood pressure. Diabetic retinopathy is common in newly diagnosed type II diabetes mellitus patients. Ophthalmologic consultation is essential at the time of diagnosis for all patients.

  11. Meeting and activating the newly unemployed

    DEFF Research Database (Denmark)

    Rotger, Gabriel Pons

    -demanding activity. As intensive activation is usually accompanied by intensive search monitoring, it is important to disentangling the contribution of the costly activation programs from that of caseworker meetings. Using Danish data for the period 2010-13, the paper shows that requiring newly unemployed intensive...... activation, contrary to job search meetings, reduces employment and increases sickness benefit claims....

  12. IMAGINE: Interstellar MAGnetic field INference Engine

    Science.gov (United States)

    Steininger, Theo

    2018-03-01

    IMAGINE (Interstellar MAGnetic field INference Engine) performs inference on generic parametric models of the Galaxy. The modular open source framework uses highly optimized tools and technology such as the MultiNest sampler (ascl:1109.006) and the information field theory framework NIFTy (ascl:1302.013) to create an instance of the Milky Way based on a set of parameters for physical observables, using Bayesian statistics to judge the mismatch between measured data and model prediction. The flexibility of the IMAGINE framework allows for simple refitting for newly available data sets and makes state-of-the-art Bayesian methods easily accessible particularly for random components of the Galactic magnetic field.

  13. Preceptors' perceptions of the elements of a successful and an unsuccessful orientation period for newly graduated nurses.

    Science.gov (United States)

    Lindfors, Kirsi; Meretoja, Riitta; Kaunonen, Marja; Paavilainen, Eija

    2018-04-01

    To identify existing orientation patterns and to find elements that may enhance or impede successful orientation of newly graduated nurses. Preceptors have first-hand information concerning orientation and their opinions should not be forgotten when organisations develop their orientation processes. An open-ended questionnaire was undertaken to collect data from preceptors (n = 172) about the current orientation patterns. Data were analysed by using deductive content analysis and by quantifying the phrases. Communal commitment to the orientation process, strong professional orientation know-how and supportive leadership were the enhancing elements of successful orientation. Complex interpersonal relationship problems during orientation, inadequate orientation resources and the organisation's structural and functional problems were the impeding elements of successful orientation. With the elements of successful orientation we ensure a supportive transition to practice for newly graduate nurses and possibilities to focus on good orientation practices for preceptors. Nurse leaders play an important part in ensuring newly graduated nurses have a safe nursing career starting point and, for preceptors, opportunities to provide orientation that is as good as possible. Supportive leadership, sufficient resources and good interpersonal relationships should be the leading principles during newly graduated nurses' orientation period. © 2017 John Wiley & Sons Ltd.

  14. Bioorthogonal Chemistry for the Isolation and Study of Newly Synthesized Histones and Their Modifications.

    Science.gov (United States)

    Arnaudo, Anna M; Link, A James; Garcia, Benjamin A

    2016-03-18

    The nucleosome is an octamer containing DNA wrapped around one histone H3-H4 tetramer and two histone H2A-H2B dimers. Within the nucleosome, histones are decorated with post-translational modifications. Previous studies indicate that the H3-H4 tetramer is conserved during DNA replication, suggesting that old tetramers serve as a template for the modification of newly synthesized tetramers. Here, we present a method that merges bioorthogonal chemistry with mass spectrometry for the study of modifications on newly synthesized histones in mammalian cells. HeLa S3 cells are dually labeled with the methionine analog azidohomoalanine and heavy (13)C6,(15)N4 isotope labeled arginine. Heavy amino acid labeling marks newly synthesized histones while azidohomoalanine incorporation allows for their isolation using bioorthogonal ligation. Labeled mononucleosomes were covalently linked via a copper catalyzed reaction to a FLAG-GGR-alkyne peptide, immunoprecipitated, and subjected to mass spectrometry for quantitative modification analysis. Mononucleosomes containing new histones were successfully isolated using this approach. Additionally, the development of this method highlights the potential deleterious effects of azidohomoalanine labeling on protein PTMs and cell cycle progression, which should be considered for future studies utilizing bioorthogonal labeling strategies in mammalian cells.

  15. Quality of life in newly diagnosed children with specific learning disabilities (SpLD) and differences from typically developing children: a study of child and parent reports.

    Science.gov (United States)

    Ginieri-Coccossis, M; Rotsika, V; Skevington, S; Papaevangelou, S; Malliori, M; Tomaras, V; Kokkevi, A

    2013-07-01

    Research on quality of life (QoL) of school children with specific learning disabilities (SpLD) and their parents is scarce. The present study explores QoL deficits in newly diagnosed children with SpLD and their parents, in comparison to a similar age group of typically developing children. Possible associations between parental and child QoL were statistically explored in both groups of children. 70 newly diagnosed children with SpLD [International Classification of Diseases-10 (ICD-10) criteria] (38 boys, 32 girls, mean age 10.1 years) and a control group of 69 typically developing children of the same age (40 boys, 29 girls, mean age 10.6 years) were recruited. Children were of normal intelligence quotient, attending mainstream schools. Their parents were also recruited so a child's scores could be associated with corresponding parental scores (mother or father). Children's QoL was assessed by the German questionnaire for measuring quality of life in children and adolescents (KINDL(R) ) questionnaire and parental QoL by World Health Organization Quality of Life brief questionnaire (WHOQOL-BREF) of the World Health Organization. Children with SpLD in comparison to typically developing children reported according to the KINDL(R) measurement poorer emotional well-being, lower self-esteem and satisfaction in their relationships with family and friends. Surprisingly, school functioning was not reported by these children as an area of concern. Parents of children with SpLD indicated experiencing lower satisfaction in the WHOQOL-BREF domains of social relationships and environment. Correlational and regression analysis with parental-child QoL scores provided evidence that in the SpLD group, parental scores on WHOQOL-BREF social relationships and psychological health domains could be predictors of the child's emotional well-being, satisfaction with family, friends and school functioning. Stepwise regression analysis verified the effect of parents' WHOQOL-BREF social

  16. An Experimental Study on Dynamics of a Novel Dual-Belt Continuous Variable Transmission Based on a Newly Developed Test Rig

    Directory of Open Access Journals (Sweden)

    Pak Kin Wong

    2015-01-01

    Full Text Available A novel dual-belt Van Doorne’s continuous variable transmission (DBVCVT system, which is applicable to heavy-duty vehicles, has been previously proposed by the authors in order to improve the low torque capacity of traditional single-belt CVT. This DBVCVT is a novel design among continuously variable transmissions and is necessary to be prototyped for experimental study, and the analytical dynamic model for this DBVCVT also needs to be experimentally validated. So, this work originally fabricated a prototype of DBVCVT and integrates this prototype to a light-load hardware-in-the-loop test rig by replacing the engine and load equipment with the AC motor and magnetic powder dynamometer. Moreover, with the use of this newly developed test rig, this work implements the experimental study of this DBVCVT for the first time. The comparison of experimental and simulation results validates the previously proposed analytical model for DBVCVT, and some basic characteristics of the DBVCVT in terms of the reliability, speed ratio, and transmission efficiency are also experimentally studied. In all, this developed test rig with the analytical model lays the foundation for further study on this novel DBVCVT.

  17. Clinical heterogeneity in newly diagnosed Parkinson's disease

    NARCIS (Netherlands)

    Post, Bart; Speelman, Johannes D.; de Haan, Rob J.

    2008-01-01

    OBJECTIVE: To determine clinical heterogeneity in newly diagnosed Parkinson's disease using cluster analysis and to describe the subgroups in terms of impairment, disability, perceived quality of life, and use of dopaminergic therapy. METHODS: We conducted a k-means cluster analysis in a prospective

  18. The development and impact of active learning strategies on self-confidence in a newly designed first-year self-care pharmacy course - outcomes and experiences.

    Science.gov (United States)

    Smith, Kathryn J; Grundmann, Oliver; Li, Robin Moorman

    2018-04-01

    The primary objective of this investigation was to determine the effectiveness of different active learning exercises in a newly-designed flipped-classroom self-care course in applying newly acquired knowledge of self-care and improving the confidence of first-year pharmacy students to recommend self-care treatments and counsel patients. The early development of these skills is essential for the subsequent Community Introductory Pharmacy Practice Experience (CIPPE). An unpaired anonymous survey was administered to students, pre- and post-course, to ascertain their opinions on the effectiveness of various teaching strategies and active learning exercises on learning and on their confidence in treatment-planning and patient counseling for self-care patients. Comparison between pre- and post-course Likert scores was conducted using a one-way ANOVA followed by a post-hoc Tukey's test with significance at p = 0.05. All other tests of significance were conducted using a student's t-test with significance at p = 0.05. Students' self-confidence in developing treatment plans and in counseling for non-prescription drugs and dietary supplements significantly improved from the beginning to the end of this self-care course. The response rate was high in both the pre- (N = 208, 88.1%) and post- (N = 198, 83.9%) course surveys. The positive change in confidence was not reflected in increased performance on the final exam represented by a lower average score than the midterm exam. Active learning sessions and the flipped classroom approach in this first-year pharmacy self-care course contributed to increased self-confidence in making recommendations and counseling patients on proper use of nonprescription medications and dietary supplements. Copyright © 2017 Elsevier Inc. All rights reserved.

  19. Response of sesame to population densities and nitrogen fertilization on newly reclaimed sandy soils

    International Nuclear Information System (INIS)

    Noorka, I.R.; Hafiz, S.I.

    2011-01-01

    Two field experiments were conducted at the Experimental Farm of Faculty of Agriculture, Suez Canal University at Ismailia during 2008 and 2009 seasons to study the effect of nitrogen fertilization and planting density on growth , yield, its attributes as well as seed quality of new sesame variety (Taka 2 cv.). On newly reclaimed sandy soils of Ismailia Governorate, Egypt, experimental design in split plots form with four replications was used. Four levels of nitrogen fertilization 55, 105, 155 and 205 Kg/ha were arranged randomly in the main plots and three planting distances between hills (10, 15 and 20 cm, respectively) were distributed at random in the sub plots. Increasing N fertilizer level up to 205 Kg/ha significantly increased plant height, fruiting zone length, height of the first fruiting branch, number of branches and capsules/plant, 1000-seed weight, seed weight/plant, seed oil content (%) and seed and oil yields /ha. Decreasing planting distance from 20 to 15 and 10 cm consistently and significantly increased plant height, height of the first fruiting branch and seed and oil yields /ha. The reverse was true regarding the yield components. These results were expected, since experiment soil was newly reclaimed sandy soil and very poor in the nutrients and organic matter. (author)

  20. High field superconductor development and understanding project, Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Larbalestier, David C.; Lee, Peter J.

    2009-07-15

    Over 25 years the Applied Superconductivity Center at the University of Wisconsin-Madison provided a vital technical resource to the High Energy Physics community covering development in superconducting strand for HEP accelerator magnet development. In particular the work of the group has been to develop the next generation of high field superconductors for high field application. Grad students Mike Naus, Chad Fischer, Arno Godeke and Matt Jewell improved our understanding of the microstructure and microchemistry of Nb3Sn and their impact on the physical and mechanical properties. The success of this work has led to the continued funding of this work at the ASC after it moved to the NHMFL and also to direct funding from BNL for some aspects of Nb3Sn cable evaluation.

  1. Study on the system development for evaluating long-term alteration of hydraulic field in Near Field 2

    International Nuclear Information System (INIS)

    Okutu, Kazuo; Morikawa, Seiji; Takamura, Hisashi

    2003-02-01

    For the high performance evaluation of reliability of TRU waste repository, the system development for evaluating long-term alteration in consideration of the changes action of barrier materials of hydraulic field in Near Field is required. In this research, the system development for evaluating long-term alteration of hydraulic field in Near Field was examined. The model evaluating each phenomena and the prototype system for chemical/mechanical analysis system were developed, and the method of coupling chemical with dynamic analysis was examined. To improve accuracy and propriety of this analysis system in the future, necessary development elements were arranged. The research result of this year is shown below. 1) Knowledge concerning the chemical phenomena in the near field evolution was rearranged. Experimental approaches and analysis methods were applied to the phenomena of which the knowledge can be obtained. Approaches to focus the model were applied to the phenomena for which knowledge is essentially difficult to obtain. The analysis model was improved using knowledge from natural analog and computational analyses. An analysis system was developed and the propriety of the model was demonstrated. 2) The model of bentonite material was developed by focusing attention on nonlinear swelling behavior. And the model of cement material was developed by focusing attention on deformation behavior influenced by leaching of calcium element which cause reducing of rigidity and strength. With regard to the bentonite model, to testify its propriety, the trial analysis result compared with the consolidation properties test data. Furthermore, the dynamic alteration action analysis system consisted of bentonite and cement model was developed, and trial analysis was performed. In this trial analysis, parameters of cation exchange ratio of Na-bentonite for Ca ion and leaching ratio of Ca from cement material were considered. On the one hand, as concerns rock, to include the

  2. [Principles of nutrition in patients with newly appointed stoma].

    Science.gov (United States)

    Pachocka, Lucyna Małgorzata; Urbanik, Anna

    2016-01-01

    The treatment of intestinal stoma is often a difficult experience for patients and results in numerous problems in the physical, psychological and social aspects. Therefore, post-operative care of the patient with the newly appointed stoma should be taken by therapeutic team consisting of doctors, nurses, physiotherapists, dieticians, psychologists and social workers. Appropriate nutritional education of patients aims to improve their quality of life and to prevent from unpleasant ailments formed after the operation. The specific type of stoma may decide about certain dietary recommendations. The presented work provides a practical dietary recommendations for patients with newly appointed stoma.

  3. Development of field navigation system; Field navigation system no kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    Ibara, S; Minode, M; Nishioka, K [Daihatsu Motor Co. Ltd., Osaka (Japan)

    1995-04-20

    This paper describes the following matters on a field navigation system developed for the purpose of covering a field of several kilometer square. This system consists of a center system and a vehicle system, and the center system comprises a map information computer and a communication data controlling computer; since the accuracy for a vehicle position detected by a GPS is not sufficient, an attempt of increasing the accuracy of vehicle position detection is made by means of a hybrid system; the hybrid system uses a satellite navigation method of differential system in which the error components in the GPS are transmitted from the center, and also uses a self-contained navigation method which performs an auxiliary function when the accuracy in the GPS has dropped; corrected GPS values, emergency messages to all of the vehicles and data of each vehicle position are communicated by wireless transmission in two ways between the center and vehicles; and accommodation of the map data adopted a system that can respond quickly to any change in roads and facilities. 3 refs., 13 figs., 1 tab.

  4. Two Newly Discovered Plants in Taiwan

    OpenAIRE

    Tian-Chuan Hsu; Jia-Jung Lin; Shih-Wen Chung

    2009-01-01

    Two herbs are newly discovered in Taiwan. Limnophila fragrans (G. Forst.) Seem. (Scrophulariaceae), native in SE Asia, is recognized from southern lowlands. Anagallis minima (L.) E. H. L. Krause (Primulaceae), native in N America and Europe, was found from northern mountainous region at low altitudes. In this study, descriptions, line drawings, color photos and a distribution map of the two species are provided.

  5. Newly-formed emotional memories guide selective attention processes: Evidence from event-related potentials.

    Science.gov (United States)

    Schupp, Harald T; Kirmse, Ursula; Schmälzle, Ralf; Flaisch, Tobias; Renner, Britta

    2016-06-20

    Emotional cues can guide selective attention processes. However, emotional stimuli can both activate long-term memory representations reflecting general world knowledge and engage newly formed memory representations representing specific knowledge from the immediate past. Here, the self-completion feature of associative memory was utilized to assess the regulation of attention processes by newly-formed emotional memory. First, new memory representations were formed by presenting pictures depicting a person either in an erotic pose or as a portrait. Afterwards, to activate newly-built memory traces, edited pictures were presented showing only the head region of the person. ERP recordings revealed the emotional regulation of attention by newly-formed memories. Specifically, edited pictures from the erotic compared to the portrait category elicited an early posterior negativity and late positive potential, similar to the findings observed for the original pictures. A control condition showed that the effect was dependent on newly-formed memory traces. Given the large number of new memories formed each day, they presumably make an important contribution to the regulation of attention in everyday life.

  6. Newly-formed emotional memories guide selective attention processes: Evidence from event-related potentials

    Science.gov (United States)

    Schupp, Harald T.; Kirmse, Ursula; Schmälzle, Ralf; Flaisch, Tobias; Renner, Britta

    2016-01-01

    Emotional cues can guide selective attention processes. However, emotional stimuli can both activate long-term memory representations reflecting general world knowledge and engage newly formed memory representations representing specific knowledge from the immediate past. Here, the self-completion feature of associative memory was utilized to assess the regulation of attention processes by newly-formed emotional memory. First, new memory representations were formed by presenting pictures depicting a person either in an erotic pose or as a portrait. Afterwards, to activate newly-built memory traces, edited pictures were presented showing only the head region of the person. ERP recordings revealed the emotional regulation of attention by newly-formed memories. Specifically, edited pictures from the erotic compared to the portrait category elicited an early posterior negativity and late positive potential, similar to the findings observed for the original pictures. A control condition showed that the effect was dependent on newly-formed memory traces. Given the large number of new memories formed each day, they presumably make an important contribution to the regulation of attention in everyday life. PMID:27321471

  7. The Momotombo Geothermal Field, Nicaragua: Exploration and development case history study

    Energy Technology Data Exchange (ETDEWEB)

    None

    1982-07-01

    This case history discusses the exploration methods used at the Momotombo Geothermal Field in western Nicaragua, and evaluates their contributions to the development of the geothermal field models. Subsequent reservoir engineering has not been synthesized or evaluated. A geothermal exploration program was started in Nicaragua in 1966 to discover and delineate potential geothermal reservoirs in western Nicaragua. Exploration began at the Momotombo field in 1970 using geological, geochemical, and geophysical methods. A regional study of thermal manifestations was undertaken and the area on the southern flank of Volcan Momotombo was chosen for more detailed investigation. Subsequent exploration by various consultants produced a number of geotechnical reports on the geology, geophysics, and geochemistry of the field as well as describing production well drilling. Geological investigations at Momotombo included photogeology, field mapping, binocular microscope examination of cuttings, and drillhole correlations. Among the geophysical techniques used to investigate the field sub-structure were: Schlumberger and electromagnetic soundings, dipole mapping and audio-magnetotelluric surveys, gravity and magnetic measurements, frequency domain soundings, self-potential surveys, and subsurface temperature determinations. The geochemical program analyzed the thermal fluids of the surface and in the wells. This report presents the description and results of exploration methods used during the investigative stages of the Momotombo Geothermal Field. A conceptual model of the geothermal field was drawn from the information available at each exploration phase. The exploration methods have been evaluated with respect to their contributions to the understanding of the field and their utilization in planning further development. Our principal finding is that data developed at each stage were not sufficiently integrated to guide further work at the field, causing inefficient use of

  8. Development of Field Angle Resolved Specific Heat Measurement System for Unconventional Superconductors

    International Nuclear Information System (INIS)

    Kitamura, Yasuhiro; Matsubara, Takeshi; Machida, Yo; Izawa, Koichi; Onuki, Yoshichika; Salce, Bernard; Flouquet, Jacques

    2015-01-01

    We developed a measurement system for field angle resolved specific heat under multiple extreme conditions at low temperature down to 50 mK, in magnetic field up to 7 T, and under high pressure up to 10 GPa. We demonstrated the performance of our developed system by measuring field angle dependence of specific heat of pressure induced unconventional superconductor CeIrSi 3

  9. Evaluation of edge enhancement effect of phase contrast imaging using newly-developed photostimulable phosphor plate

    International Nuclear Information System (INIS)

    Matsuo, Satoru; Morishita, Junji; Katafuchi, Tetsuro; Fujita, Hiroshi

    2012-01-01

    We investigated whether the use of a newly developed columnar-crystal-type photostimulable-phosphor plate (CP1M200, referred to as system C) helps to provide improved edge-enhanced effect in phase contrast imaging. Physical characteristics of 2 conventional particulate-crystal-type photostimulable-phosphor plates (RP-5PM, referred to as system A and RP-6M, referred to as system B) and system C were measured. Then, an acrylic plate phantom and RMI152 phantom were imaged using 3 types of plates, and the edge-enhancement effects were evaluated based on the profile curve of the acrylic plate phantom. Visual evaluation of the RMI152 phantom images was conducted. The results showed that the modulation transfer function (MTF) of system C was superior to those of the other systems. The WS of system C was superior to those of the other systems in the low frequency band region, and inferior to those of the other systems in the high frequency band region. The presence of an edge-enhanced image was not detectable in the profile curve of the acrylic plate in system A, although that was shown in systems B and C due to their excellent sharpness. In the visual image evaluation of the RMI152 phantom, image quality of system C was superior to those of the other systems. Phase contrast imaging with a digital detector of a columnar-crystal-type photostimulable-phosphor plate is considered to provide improved edge-enhancement over that of conventional plates. (author)

  10. Newly developed liquid-based cytology. TACAS™: cytological appearance and HPV testing using liquid-based sample.

    Science.gov (United States)

    Kubushiro, Kaneyuki; Taoka, Hideki; Sakurai, Nobuyuki; Yamamoto, Yasuhiro; Kurasaki, Akiko; Asakawa, Yasuyuki; Iwahara, Minoru; Takahashi, Kei

    2011-09-01

    Cell profiles determined by the thin-layer advanced cytology assay system (TACAS™), a liquid-based cytology technique newly developed in Japan, were analyzed in this study. Hybrid capture 2 (HC-2) was also performed using the liquid-based samples prepared by TACAS to ascertain its ability to detect human papillomavirus (HPV). Cell collection samples from uterine cervix were obtained from 359 patients and examined cytologically. A HC-2 assay for HPV was carried out in the cell specimens. All specimens were found to show background factors such as leukocytes. After excluding the 5 unsatisfactory cases from the total 354 cases, 82 cases (23.2%) were positive and 272 cases (76.8%) were negative for HPV. Cell specimens from 30 HPV-positive cases and 166 HPV-negative cases were subjected to 4 weeks of preservation at room temperature. Then, when subsequently re-assayed, 28 cases (93.3%) in the former group were found to be HPV positive and 164 cases (98.8%) in the latter group were found to be HPV negative. These results supported the excellent reproducibility of TACAS for HPV testing. A reasonable inference from the foregoing analysis is that TACAS may be distinguished from other liquid-based cytological approaches, such as ThinPrep and SurePath, in that it can retain the cell backgrounds. Furthermore, this study raises the possibility that cell specimens prepared using TACAS could be preserved for at least 4 weeks prior to carrying out a HC-2 assay for HPV.

  11. Application of integrated petroleum reservoir study for intervention and field development program in western onshore field, India

    Directory of Open Access Journals (Sweden)

    Vijai Kumar Baskaran

    2017-12-01

    Full Text Available In this research, an integrated reservoir study is performed in the J#Field (J-Oil Field of western onshore, India to evaluate its additional reserves expectations and implement field developments plan using waterflood pilot program. The target strata includes two formations of Paleogene, which is about 3600 ft, namely G#Fm (G-Formation of the Eocene and T#Fm (T-Formation of Oligocene, subdivided into 11 zones. Based on these results, an attempt was made to construct of an optimization plan to exploit it, taking into account that the field is producing since 1947, with a cumulative production of 183.5 MMbbl and an overall recovery factor of 28% until January 2016. On the basis of the potential evaluation and geological modeling, blocks J48 and J45 were simulated, and the remaining oil distribution characteristics in two blocks were studied after history match. The work includes the stratigraphic studies, seismic study, logging interpretation, sedimentary facies modeling, three dimensional geological modeling, simulations for waterflooding, and future field development plans.

  12. Near field communication recent developments and library implications

    CERN Document Server

    McHugh, Sheli

    2014-01-01

    Near Field Communication is a radio frequency technology that allows objects, such as mobile phones, computers, tags, or posters, to exchange information wirelessly across a small distance. This report on the progress of Near Field Communication reviews the features and functionality of the technology and summarizes the broad spectrum of its current and anticipated applications. We explore the development of NFC technology in recent years, introduce the major stakeholders in the NFC ecosystem, and project its movement toward mainstream adoption. Several examples of early implementation of NFC

  13. Pollen parameters estimates of genetic variability among newly ...

    African Journals Online (AJOL)

    Pollen parameters estimates of genetic variability among newly selected Nigerian roselle (Hibiscus sabdariffa L.) genotypes. ... Estimates of some pollen parameters where used to assess the genetic diversity among ... HOW TO USE AJOL.

  14. Tricks of the trade: time management tips for newly qualified doctors.

    Science.gov (United States)

    Offiah, Gozie; Doherty, Eva

    2018-03-01

    The transition from medical student to doctor is an important milestone. The discovery that their time is no longer their own and that the demands of their job are greater than the time they have available is extremely challenging. At a recent surgical boot camp training programme, 60 first-year surgical trainees who had just completed their internship were invited to reflect on the lessons learnt regarding effective time management and to recommend tips for their newly qualified colleagues. They were asked to identify clinical duties that were considered urgent and important using the time management matrix and the common time traps encountered by newly qualified doctors. The surgical trainees identified several practical tips that ranged from writing a priority list to working on relationships within the team. These tips are generic and so applicable to all newly qualified medial doctors. We hope that awareness of these tips from the outset as against learning them through experience will greatly assist newly qualified doctors. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  15. Recent developments at the high-field laboratory of Tohoku University

    International Nuclear Information System (INIS)

    Motokawa, M.; Watanabe, K.; Miura, S.; Awaji, S.; Nojiri, H.; Mogi, I.; Mitsudo, S.; Sakon, T.

    1998-01-01

    Recent developments and experiments performed at the high-field laboratory of Tohoku University are described. We have (1) hybrid magnets which produce high fields up to 31.1 T, (2) liquid-helium-free superconducting magnets up to 11 T which are available continuously for more than a year, (3) a 20 T superconducting magnet, (4) pulsed field magnets up to 40 T by a 100 kJ bank and (5) repeating pulsed field systems up to 25 T, synchronized with a pulsed neutron source

  16. Chest Radiographic Findings in Newly Diagnosed Pulmonary ...

    African Journals Online (AJOL)

    Five hundred newly diagnosed cases of Pulmonary Tuberculosis were treated with directly observed short-course treatment and 100 of them had chest radiographic examination done. The various chest radiographic patterns in the 100 subjects were studied and included: Fluffy exudative changes 80(80%), fibrosis 70(70%) ...

  17. Validating self-reported mobile phone use in adults using a newly developed smartphone application.

    Science.gov (United States)

    Goedhart, Geertje; Kromhout, Hans; Wiart, Joe; Vermeulen, Roel

    2015-11-01

    Interpretation of epidemiological studies on health effects from mobile phone use is hindered by uncertainties in the exposure assessment. We used a newly developed smartphone application (app) to validate self-reported mobile phone use and behaviour among adults. 107 participants (mean age 41.4 years) in the Netherlands either downloaded the software app on their smartphone or were provided with a study smartphone for 4 weeks. The app recorded the number and duration of calls, text messages, data transfer, laterality and hands-free use. Self-reported mobile phone use was collected before using the app and after 6 months through an interviewer-administered questionnaire. The geometric mean ratios (GMR, 95% CI) and Spearman correlations (r) of self-reported (after 6 months) versus recorded number and duration of calls were: GMR=0.65 (0.53 to 0.80), r=0.53; and GMR=1.11 (0.86 to 1.42), r=0.57 respectively. Participants held the phone on average for 86% of the total call time near the head. Self-reported right side users held the phone for 70.7% of the total call time on the right side of the head, and left side users for 66.2% on the left side of the head. The percentage of total call time that the use of hands-free devices (headset, speaker mode, Bluetooth) was recorded increased with increasing frequency of reported hands-free device usage. The observed recall errors and precision of reported laterality and hands-free use can be used to quantify and improve radiofrequency exposure models based on self-reported mobile phone use. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  18. Application of the newly developed Japanese adenosine normal database for adenosine stress myocardial scintigraphy.

    Science.gov (United States)

    Harata, Shingo; Isobe, Satoshi; Morishima, Itsuro; Suzuki, Susumu; Tsuboi, Hideyuki; Sone, Takahito; Ishii, Hideki; Murohara, Toyoaki

    2015-10-01

    The currently available Japanese normal database (NDB) in stress myocardial perfusion scintigraphy recommended by the Japanese Society of Nuclear Medicine (JSNM-NDB) is created based on the data from exercise tests. The newly developed adenosine normal database (ADS-NDB) remains to be validated for patients undergoing adenosine stress test. We tested whether the diagnostic accuracy of adenosine stress test is improved by the use of ADS-NDB (Kanazawa University). Of 233 consecutive patients undergoing (99m)Tc-MIBI adenosine stress test, 112 patients were tested. The stress/rest myocardial (99m)Tc-MIBI single-photon emission computed tomography (SPECT) images were analyzed by AutoQUANT 7.2 with both ADS-NDB and JSNM-NDB. The summed stress score (SSS) and summed difference score (SDS) were calculated. The agreements of the post-stress defect severity between ADS-NDB and JSNM-NDB were assessed using a weighted kappa statistic. In all patients, mean SSSs of all, right coronary artery (RCA), left anterior descending (LAD), and left circumflex (LCx) territories were significantly lower with ADS-NDB than those with JSNM-NDB. Mean SDSs in all, RCA, and LAD territories were significantly lower with ADS-NDB than those with JSNM-NDB. In 28 patients with significant coronary stenosis, the mean SSS in the RCA territory was significantly lower with ADS-NDB than that with JSNM-NDB. In 84 patients without ischemia, both mean SSSs and SDSs in all, RCA, LAD, and LCx territories were significantly lower with ADS-NDB than those with JSNM-NDB. Weighted kappa values of all patients, patients with significant stenosis, and patients without ischemia were 0.89, 0.83, and 0.92, respectively. Differences were observed between results from ADS-NDB and JSNM-NDB. The diagnostic accuracy of adenosine stress myocardial perfusion scintigraphy may be improved by reducing false-positive results.

  19. Preparation and Evaluation of Newly Developed Chitosan Salt Coating Dispersions for Colon Delivery without Requiring Overcoating.

    Science.gov (United States)

    Yamada, Kyohei; Iwao, Yasunori; Bani-Jaber, Ahmad; Noguchi, Shuji; Itai, Shigeru

    2015-01-01

    Although chitosan (CS) has been recognized as a good material for colon-specific drug delivery systems, an overcoating with an enteric coating polymer on the surface of CS is absolutely necessary because CS is soluble in acidic conditions before reaching the colon. In the present study, to improve its stability in the presence of acid, a newly developed CS-laurate (CS-LA) material was evaluated as a coating dispersion for the development of colon-specific drug delivery systems. Two types of CS with different molecular weights, CS250 and CS600, were used to prepare CS-LA films by the casting method. The CS250-LA films had smooth surfaces, whereas the surfaces of the CS600-LA films were rough, indicating that the CS250-LA dispersion could form a denser film than CS600-LA. Both of these CS-LA films maintained a constant shape over 22 h in a pH 1.2 HCl/NaCl buffer, where the corresponding CS films rapidly disintegrated. In addition, the CS250-LA film showed specific colon degradability in a pH 6.0 phosphate buffered solution containing 1.0% (w/v) β-glucosidase. As a result of tensile strength and elongation at the break, both CS-LA films were found to have flexible film properties. Finally, the release of acetaminophen from disks coated with CS250-LA dispersions was significantly suppressed in fluids at pH 1.2 and 6.8, whereas disks coated with CS solution rapidly released the drug in pH 1.2 fluids. Taken together, this study shows that LA modification could be a useful approach in preparing CS films with acid stability and colonic degradability properties without requiring overcoating.

  20. Developing Kazakhstan's Tengiz field will be a tough task

    International Nuclear Information System (INIS)

    Samoilov, B.V.

    1993-01-01

    This paper reviews a new joint venture between the Chevron and Kazakh representatives to develop one of the world's largest oil fields under very challenging climatic and environmental conditions. It is proposed that a production of 700,000 barrels-of-oil per day will be reached by the year 2010. The paper reviews the historical development of this joint venture and discusses the proposed cost and profit-sharing proposed. It then discusses the geologic and environmental conditions which will cause extreme problems in the field development. These include climate extremes, probability of flooding, overpressured systems, corrosive brines and ground water, and poor soil conditions for construction of any facilities. It discusses a proposed plan to address each of these issues and the possible construction of oil and gas processing facilities, sulfur recovery facilities, and pipelines

  1. Solar Field Mapping and Dynamo Behavior

    Directory of Open Access Journals (Sweden)

    Kenneth H. Schatten

    2012-01-01

    Full Text Available We discuss the importance of the Sun’s large-scale magnetic field to the Sun-Planetary environment. This paper narrows its focus down to the motion and evolution of the photospheric large-scale magnetic field which affects many environments throughout this region. For this purpose we utilize a newly developed Netlogo cellular automata model. The domain of this algorithmic model is the Sun’s photosphere. Within this computational space are placed two types of entities or agents; one may refer to them as bluebirds and cardinals; the former carries outward magnetic flux and the latter carries out inward magnetic flux. One may simply call them blue and red agents. The agents provide a granularity with discrete changes not present in smooth MHD models; they undergo three processes: birth, motion, and death within the photospheric domain. We discuss these processes, as well as how we are able to develop a model that restricts its domain to the photosphere and allows the deeper layers to be considered only through boundary conditions. We show the model’s ability to mimic a number of photospheric magnetic phenomena: the solar cycle (11-year oscillations, the Waldmeier effect, unipolar magnetic regions (e.g. sectors and coronal holes, Maunder minima, and the march/rush to the poles involving the geometry of magnetic field reversals. We also discuss why the Sun sometimes appears as a magnetic monopole, which of course requires no alteration of Maxwell’s equations.

  2. Two Newly Discovered Plants in Taiwan

    Directory of Open Access Journals (Sweden)

    Tian-Chuan Hsu

    2009-11-01

    Full Text Available Two herbs are newly discovered in Taiwan. Limnophila fragrans (G. Forst. Seem. (Scrophulariaceae, native in SE Asia, is recognized from southern lowlands. Anagallis minima (L. E. H. L. Krause (Primulaceae, native in N America and Europe, was found from northern mountainous region at low altitudes. In this study, descriptions, line drawings, color photos and a distribution map of the two species are provided.

  3. Directions for Development of the Field of Electroactive Polymer (EAP)

    Science.gov (United States)

    Bar-Cohen, Yoseph

    2011-01-01

    In last few years, the rate of development and advances in the field of EAP has accelerated significantly and it is increasingly getting closer to the point of finding them used in commercial products. Substantial development has been reported in the understanding of their drive mechanisms and the parameters that control their electro-activation behavior. Further, efforts are being made to develop mass production techniques with greatly improved actuation capability and operation durability. The recent efforts to develop energy harvesting techniques, haptic interfacing (including refreshable braille displays), and toys are further increasing the likelihood of finding niches for these materials. In this paper, the author sought to examine the potential directions for the future development of the field of EAP in relation to the state-of-the-art.

  4. Diabetes education and self-management for ongoing and newly diagnosed (DESMOND)

    DEFF Research Database (Denmark)

    Skinner, T. Chas; Carey, Marian E.; Cradock, Sue

    2006-01-01

    diagnosed with Type 2 diabetes changes key illness beliefs and that these changes predict quality of life and metabolic control at 3-month follow-up. Practice implications: Newly diagnosed individuals are open to attending self-management programs and, if the program is theoretically driven, can......Objective: To determine the effects of a structured education program on illness beliefs, quality of life and physical activity in people newly diagnosed with Type 2 diabetes. Methods: Individuals attending a diabetes education and self-management for ongoing and newly diagnosed (DESMOND) program...... in 12 Primary Care Trusts completed questionnaire booklets assessing illness beliefs and quality of life at baseline and 3-month follow-up, metabolic control being assessed through assay of HbA1c. Results: Two hundred and thirty-six individuals attended the structured self-management education sessions...

  5. Collaborative Technology Assessments Of Transient Field Processing And Additive Manufacturing Technologies As Applied To Gas Turbine Components

    Energy Technology Data Exchange (ETDEWEB)

    Ludtka, Gerard Michael [ORNL; Dehoff, Ryan R [ORNL; Szabo, Attila [General Electric (GE) Power and Water; Ucok, Ibrahim [General Electric (GE) Power and Water

    2016-01-01

    ORNL partnered with GE Power & Water to investigate the effect of thermomagnetic processing on the microstructure and mechanical properties of GE Power & Water newly developed wrought Ni-Fe-Cr alloys. Exploration of the effects of high magnetic field process during heat treatment of the alloys indicated conditions where applications of magnetic fields yields significant property improvements. The alloy aged using high magnetic field processing exhibited 3 HRC higher hardness compared to the conventionally-aged alloy. The alloy annealed at 1785 F using high magnetic field processing demonstrated an average creep life 2.5 times longer than that of the conventionally heat-treated alloy. Preliminary results show that high magnetic field processing can improve the mechanical properties of Ni-Fe-Cr alloys and potentially extend the life cycle of the gas turbine components such as nozzles leading to significant energy savings.

  6. NEWLY DISCOVERED GLOBAL TEMPERATURE STRUCTURES IN THE QUIET SUN AT SOLAR MINIMUM

    Energy Technology Data Exchange (ETDEWEB)

    Huang Zhenguang; Frazin, Richard A.; Landi, Enrico; Manchester, Ward B.; Gombosi, Tamas I. [Department of Atmospheric, Oceanic, and Space Sciences, University of Michigan, Ann Arbor, MI 48109 (United States); Vasquez, Alberto M. [Instituto de Astronomia y Fisica del Espacio, CONICET-University of Buenos Aires, Ciudad de Buenos Aires, CC 67-Suc 28 (Argentina)

    2012-08-20

    Magnetic loops are building blocks of the closed-field corona. While active region loops are readily seen in images taken at EUV and X-ray wavelengths, quiet-Sun (QS) loops are seldom identifiable and are therefore difficult to study on an individual basis. The first analysis of solar minimum (Carrington Rotation 2077) QS coronal loops utilizing a novel technique called the Michigan Loop Diagnostic Technique (MLDT) is presented. This technique combines Differential Emission Measure Tomography and a potential field source surface (PFSS) model, and consists of tracing PFSS field lines through the tomographic grid on which the local differential emission measure is determined. As a result, the electron temperature T{sub e} and density N{sub e} at each point along each individual field line can be obtained. Using data from STEREO/EUVI and SOHO/MDI, the MLDT identifies two types of QS loops in the corona: so-called up loops in which the temperature increases with height and so-called down loops in which the temperature decreases with height. Up loops are expected, however, down loops are a surprise, and furthermore, they are ubiquitous in the low-latitude corona. Up loops dominate the QS at higher latitudes. The MLDT allows independent determination of the empirical pressure and density scale heights, and the differences between the two remain to be explained. The down loops appear to be a newly discovered property of the solar minimum corona that may shed light on the physics of coronal heating. The results are shown to be robust to the calibration uncertainties of the EUVI instrument.

  7. Full-Wave Analysis of Traveling-Wave Field-Effect Transistors Using Finite-Difference Time-Domain Method

    Directory of Open Access Journals (Sweden)

    Koichi Narahara

    2012-01-01

    Full Text Available Nonlinear transmission lines, which define transmission lines periodically loaded with nonlinear devices such as varactors, diodes, and transistors, are modeled in the framework of finite-difference time-domain (FDTD method. Originally, some root-finding routine is needed to evaluate the contributions of nonlinear device currents appropriately to the temporally advanced electrical fields. Arbitrary nonlinear transmission lines contain large amount of nonlinear devices; therefore, it costs too much time to complete calculations. To reduce the calculation time, we recently developed a simple model of diodes to eliminate root-finding routines in an FDTD solver. Approximating the diode current-voltage relation by a piecewise-linear function, an extended Ampere's law is solved in a closed form for the time-advanced electrical fields. In this paper, we newly develop an FDTD model of field-effect transistors (FETs, together with several numerical examples that demonstrate pulse-shortening phenomena in a traveling-wave FET.

  8. Nuclear material accounting and control: Co-ordinating assistance to newly independent States

    International Nuclear Information System (INIS)

    Thorstensen, S.

    1995-01-01

    This article outlines work under way among the IAEA, its Member States, and the Newly Independent States (NIS) relating to the establishment and development in the NIS of State Systems of Accounting and Control (SSACs) of nuclear material. It describes IAEA activities in the NIS, including fact-finding missions at technical visits, the successful attempts to find donor States providing voluntary funding and expertise, and the co-ordination of technical support between the IAEA and the donor States. 3 tabs

  9. Geology and development of oil fields in Western Siberia

    Energy Technology Data Exchange (ETDEWEB)

    1980-01-01

    The anthology is dedicated to the geology, geophysics, hydrodynamics, and development of oil fields in Western Siberia. The articles on geological, industrial-geophysical and theoretical mathematical studies make recommendations and suggest measures to improve procedures for calculating oil reserves, to increase development efficiency and raise oil output.

  10. Development of human exposure standards for radio frequency fields

    International Nuclear Information System (INIS)

    Lin, James C.

    2000-01-01

    Historical aspects of the problem of developing human exposure standards for radio frequency (RF) electromagnetic fields are discussed. It is shown that biological effects and health implications of radiofrequency (RF) electromagnetic fields have been a subject of scientific investigation for more than 50 years. It has become a focus of attention because of the expanded use of RF radiation in the frequency range between 300 MHz and 6 GHz for wireless communication over the past decade. Another cause for the attention is the uncertainty of some observed responses and lack of understanding of the mechanism of interaction of RF electromagnetic fields with biological systems. At present, considerable efforts are devoted to developing and revising RF exposure standards. Each of these efforts should aim to make explicit the philosophy and process by which they reason and decide guidelines for deeming exposure as safe. Furthermore, the reconciliation of philosophies of protection will definitely be an asset, in practice, to those interested in international harmonization of RF exposure standards [ru

  11. Developments of saddle field ion sources and their applications

    International Nuclear Information System (INIS)

    Abdelrahman, M.M.; Helal, A.G.

    2009-01-01

    Ion sources should have different performance parameters according to the various applications for which they are used, ranging from ion beam production to high energy ion implanters. There are many kinds of ion sources, which produce different ion beams with different characteristics. This paper deals with the developments and applications of some saddle field ion sources which were designed and constructed in our lab. Theory of operation and types of saddle field ion sources are discussed in details. Some experimental results are given. The saddle field ion sources operate at low gas pressure and require neither magnetic field nor filament. This type of ion sources is used for many different applications as ion beam machining, sputtering, cleaning and profiling for surface analysis etc

  12. Profiles of alpha-melanocyte-stimulating hormone in the Japanese flounder as revealed by a newly developed time-resolved fluoroimmunoassay and immunohistochemistry.

    Science.gov (United States)

    Amiya, Noriko; Amano, Masafumi; Takahashi, Akiyoshi; Yamanome, Takeshi; Yamamori, Kunio

    2007-03-01

    Profiles of alpha-melanocyte-stimulating hormone (alpha-MSH) in the Japanese flounder were examined by a newly developed time-resolved fluoroimmunoassay (TR-FIA) and immunohistochemistry. A TR-FIA for alpha-MSH was newly developed, and its levels in the pituitary gland and plasma of Japanese flounder reared in a white or black tank for 5 months were compared. A competitive assay using two antibodies was performed among secondary antibodies in the solid phase, alpha-MSH antibodies, samples, and europium-labeled Des-Ac-alpha-MSH. The sensitivity of the assay, defined as twice the standard deviation at a zero dose, was 0.98 ng/ml (49 pg/well). The intra- and interassay coefficients of variation of the assay were 8.8% (n=8) and 17.3% (n=5), respectively, at about 50% binding. Cross-reactivities of Des-Ac-alpha-MSH and Di-Ac-alpha-MSH were about 100%. Cross-reactivities of adrenocorticotropic hormone, salmon gonadotropin-releasing hormone (sGnRH), and chicken GnRH-II were less than 0.2%, and that of melanin-concentrating hormone was less than 2.0% at 50% binding. Displacement curves of serially twofold-diluted hypothalamus extract, pituitary gland extract, and plasma extract of Japanese flounder with the assay buffer were parallel to the alpha-MSH standard curve. Moreover, displacement curves of serially twofold-diluted hypothalamus and/or pituitary gland extract of masu salmon, goldfish, red seabream, Japanese eel, tiger puffer, and barfin flounder with the assay buffer were also parallel to the alpha-MSH standard. In Japanese flounder, total immunoreactive (ir)-alpha-MSH levels in the pituitary gland were lower in the black tank, whereas those in the plasma tended to be higher in the black tank, suggesting that the synthesis and release of alpha-MSH are higher in the black tank. alpha-MSH-ir cells were detected in the pars intermedia and a small part of the pars distalis of the pituitary gland. alpha-MSH-ir cell bodies were located in the basal hypothalamus and alpha

  13. Situation and role of industrial fields in nuclear fusion reactor development

    International Nuclear Information System (INIS)

    Suzuki, Gen-ichi

    1983-01-01

    Japan Atomic Industrial Forum (JAIF) established the nuclear fusion technical committee in October, 1980, and has investigated the attitude of industrial fields in progressing nuclear fusion research and development and the measures to cooperate with national development plans. Corresponding to the new long term plan and the establishment of the basic policy for nuclear fusion research and development by Atomic Energy Commission of Japan in June, 1982, JAIF has settled the policy on the situation and role of industrial fields. In this report, first the necessity of firmly grasping the position of nuclear fusion research in atomic energy development is described, next, the present status of the research and development in Japan is reported, and it is mentioned that the role of manufacturers in reinforcing engineering has become more important in industrial fields. In the stage of the construction of a nuclear fusion reactor, the experiences in the engineering safety in fission reactors, environmental safety and system engineering will be utilized. Japanese industrial fields feature that they have made larger cooperation with national projects even in the research and development stage as compared to foreign countries. When the plan of next phase system will be promoted in the future, the cooperating methods in the past should be evaluated, investigated and improved, and the experiences in fast breeder reactors and advanced heavy water reactors should be referred to. Finally, the problems and the countermeasures in nuclear fusion development are described. (Wakatsuki, Y.)

  14. 'Practising under your own Pin'- a description of the transition experiences of newly qualified midwives.

    Science.gov (United States)

    Avis, Mark; Mallik, Maggie; Fraser, Diane M

    2013-11-01

    Transition experiences of newly qualified midwives were examined in depth during the third phase of a UK evaluation study of midwifery education. The fitness to practise and the retention of newly qualified nursing and midwifery graduates are pressing concerns for health care managers. The advantages of preceptorship are reported in the literature but the content and timing of schemes remain unclear. A semi-structured diary was kept for up to 6 months by 35 newly qualified midwives in 18 work sites covering all countries in the UK. The preceptor and supervisor of midwives for each newly qualified midwife completed short questionnaires about their preceptee's performance, and a further sub-sample of newly qualified midwives and preceptors participated in a semi-structured interview. Data were analysed to elicit aspects of newly qualified midwives transition experiences. Findings confirm that structured preceptorship schemes are not widely available. Newly qualified midwives primarily obtained transition support from members of the midwifery team. Although perceived as competent, there is no demarcation point in becoming confident to practise as a registered practitioner. Implications for managers include the importance of a supportive culture within clinical teams for successful transition and the introduction of structured preceptorship schemes facilitated by appropriate rotation patterns. © 2012 John Wiley & Sons Ltd.

  15. Music-based Autism Diagnostics (MUSAD) - A newly developed diagnostic measure for adults with intellectual developmental disabilities suspected of autism.

    Science.gov (United States)

    Bergmann, Thomas; Sappok, Tanja; Diefenbacher, Albert; Dames, Sibylle; Heinrich, Manuel; Ziegler, Matthias; Dziobek, Isabel

    2015-01-01

    The MUSAD was developed as a diagnostic observational instrument in an interactional music framework. It is based on the ICD-10/DSM-5 criteria for autism spectrum disorder (ASD) and was designed to assess adults on a lower level of functioning, including individuals with severe language impairments. This study aimed to evaluate the psychometric properties of the newly developed instrument. Calculations were based on a consecutive clinical sample of N=76 adults with intellectual and developmental disabilities (IDD) suspected of ASD. Objectivity, test-retest reliability, and construct validity were calculated and a confirmatory factor analysis was applied to verify a reduced and optimized test version. The structural model showed a good fit, while internal consistency of the subscales was excellent (ω>.92). Item difficulties ranged between .04≤pi≤.82 and item-total correlation from .21 to .85. Objectivity was assessed by comparing the scorings of two external raters based on a subsample of n=12; interrater agreement was .71 (ICC 2, 1). Reliability was calculated for four test repetitions: the average ICC (3, 1) was .69. Convergent ASD measures correlated significantly with the MUSAD, while the discriminant Modified Overt Aggression Scale (MOAS) showed no significant overlap. Confirmation of factorial structure and acceptable psychometric properties suggest that the MUSAD is a promising new instrument for diagnosing ASD in adults with IDD. Copyright © 2015 Elsevier Ltd. All rights reserved.

  16. The use of EORTC measures in daily clinical practice-A synopsis of a newly developed manual.

    Science.gov (United States)

    Wintner, Lisa M; Sztankay, Monika; Aaronson, Neil; Bottomley, Andrew; Giesinger, Johannes M; Groenvold, Mogens; Petersen, Morten Aa; van de Poll-Franse, Lonneke; Velikova, Galina; Verdonck-de Leeuw, Irma; Holzner, Bernhard

    2016-11-01

    Cancer has increasingly become a chronic condition and the routine collection of patient-reported outcomes (PROs) like quality of life is widely recommended for clinical practice. Nonetheless, the successful implementation of PROs is still a major challenge, although common barriers to and facilitators of their beneficial use are well known. To support health care professionals and other stakeholders in the implementation of the EORTC PRO measures, the EORTC Quality of Life Group provides guidance on issues considered important for their use in daily clinical practice. Herein, we present an outline of the newly developed "'Manual for the use of EORTC measures in daily clinical practice", covering the following issues: * a rationale for using EORTC measures in routine care *selection of EORTC measures, timing of assessments, scoring and presentation of results * aspects of a strategic implementation * electronic data assessment and telemonitoring, and * further use of EORTC measures and ethical considerations. Next to an extensive overview of currently available literature, the manual specifically focuses on knowledge about EORTC measures to give evidence-based recommendations whenever possible and to encourage readers and end-users of EORTC measures to contribute to further needed high-quality research. The manual will be accessible on the EORTC Quality of Life Group website's homepage and will be periodically updated to take into account any new knowledge due to medical, technical, regulatory and scientific advances. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  17. Study on the system development for evaluating long-term alteration of hydraulic field in Near Field. 3

    International Nuclear Information System (INIS)

    Okutu, Kazuo; Morikawa, Seiji; Taguchi, Katsunori

    2004-02-01

    For the high performance evaluation of reliability of TRU waste repository, the system development for evaluating long-term alteration in consideration of the changes action of barrier materials of hydraulic field in Near Fields is required. In this research, the system development for evaluating the long-term alteration of hydraulic field in near field was examined. The 'Evidential Support logic' for ensuring the long-term stability of the repository was developed and evaluated. Furthermore, the developed chemical/mechanical alteration action analysis system was verified and improved. The system was coupled for the long-term alteration evaluation analysis. The research results of this year are shown below. 1) A logic tree was constructed for the purpose of supporting the high performance evaluation of reliability of a TRU waste repository. The thesis that the long term safety of the TRU waste repository is preserved was ramified into subsidiary theses until all the final theses were supported by objective evidence. The probability of the subsidiary thesis supporting the upper thesis was established by interviewing specialists. The reliability of the thesis was evaluated by applying present knowledge. Furthermore, the sensitivity of the reliability of the highest thesis to increasing reliability of evidence was investigated. Appropriate targets for experiment and analysis were presented based on the sensitivity of evidence. 2) The object of the hydraulic - chemical analysis was determined from the above-mentioned logic tree. The analysis system was improved to perform the 2D analysis. A user interface was developed to simplify the setting of analysis conditions. The system was demonstrated by comparing the results with the experimental results. Furthermore, the system was applied to the near field problem to fix the condition that the safety of the TRU waste repository is preserved. 3) Both the model of bentonite material and the model of cement material were

  18. Recent Development of an Earth Science App - FieldMove Clino

    Science.gov (United States)

    Vaughan, Alan; Collins, Nathan; Krus, Mike; Rourke, Peter

    2014-05-01

    As geological modelling and analysis move into 3D digital space, it becomes increasingly important to be able to rapidly integrate new data with existing databases, without the potential degradation caused by repeated manual transcription of numeric, graphical and meta-data. Digital field mapping offers significant benefits when compared with traditional paper mapping techniques, in that it can directly and interactively feed and be guided by downstream geological modelling and analysis. One of the most important pieces of equipment used by the field geologists is the compass clinometer. Midland Valley's development team have recently release their highly anticipated FieldMove Clino App. FieldMove Clino is a digital compass-clinometer for data capture on a smartphone. The app allows the user to use their phone as a traditional hand-held bearing compass, as well as a digital compass-clinometer for rapidly measuring and capturing the georeferenced location and orientation of planar and linear features in the field. The user can also capture and store digital photographs and text notes. FieldMove Clino supports online Google Maps as well as offline maps, so that the user can import their own georeferenced basemaps. Data can be exported as comma-separated values (.csv) or Move™ (.mve) files and then imported directly into FieldMove™, Move™ or other applications. Midland Valley is currently pioneering tablet-based mapping and, along with its industrial and academic partners, will be using the application in field based projects throughout this year and will be integrating feedback in further developments of this technology.

  19. Yield and Adaptability Evaluation of Newly Introduced Tomato ...

    African Journals Online (AJOL)

    High yield is a major ambition to tomato plant breeders and farmers. The purpose of the ... Tabora Region on the growth and yield of newly introduced tomato varieties. The tested ..... (1985). Evaluation of some American tomatocultivars grown.

  20. Newly elected IAEA Board of Governors

    International Nuclear Information System (INIS)

    2000-01-01

    The document gives information about the election of 11 Member States to the IAEA Board of Governors, the 35-member policy-making body, during the 44th regular session of the IAEA's General Conference (18 - 22 September 2000, Austria Center, Vienna). The newly elected Member States are: Argentina, Egypt, Ghana, Ireland, Libyan Arab Jamahiriya, Mexico, Pakistan, Peru, Switzerland, Thailand, Ukraine. The other 24 Member States of the Board are also given

  1. Incorporating Geoscience, Field Data Collection Workflows into Software Developed for Mobile Devices

    Science.gov (United States)

    Vieira, D. A.; Mookerjee, M.; Matsa, S.

    2014-12-01

    Modern geological sciences depend heavily on investigating the natural world in situ, i.e., within "the field," as well as managing data collections in the light of evolving advances in technology and cyberinfrastructure. To accelerate the rate of scientific discovery, we need to expedite data collection and management in such a way so as to not interfere with the typical geoscience, field workflow. To this end, we suggest replacing traditional analog methods of data collection, such as the standard field notebook and compass, with primary digital data collection applications. While some field data collecting apps exist for both the iOS and android operating systems, they do not communicate with each other in an organized data collection effort. We propose the development of a mobile app that coordinates the collection of GPS, photographic, and orientation data, along with field observations. Additionally, this application should be able to pair with other devices in order to incorporate other sensor data. In this way, the app can generate a single file that includes all field data elements and can be synced to the appropriate database with ease and efficiency. We present here a prototype application that attempts to illustrate how digital collection can be integrated into a "typical" geoscience, field workflow. The purpose of our app is to get field scientists to think about specific requirements for the development of a unified field data collection application. One fundamental step in the development of such an app is the community-based, decision-making process of adopting certain data/metadata standards and conventions. In August of 2014, on a four-day field trip to Yosemite National Park and Owens Valley, we engaged a group of field-based geologists and computer/cognitive scientists to start building a community consensus on these cyberinfrastructure-related issues. Discussing the unique problems of field data recording, conventions, storage, representation

  2. Circulating mesencephalic astrocyte-derived neurotrophic factor is increased in newly diagnosed prediabetic and diabetic patients, and is associated with insulin resistance.

    Science.gov (United States)

    Wu, Tong; Zhang, Fang; Yang, Qiu; Zhang, Yuwei; Liu, Qinhui; Jiang, Wei; Cao, Hongyi; Li, Daigang; Xie, Shugui; Tong, Nanwei; He, Jinhan

    2017-04-29

    Evidence has shown that endoplasmic reticulum (ER) stress was involved in the progression to type 2 diabetes mellitus (T2DM) and development of insulin resistance. Mesencephalic astrocyte-derived neurotrophic factor (MANF) is a novel secreted protein upregulated by ER stress. This study aimed to assess serum level of MANF in normal glucose tolerance (NGT) participants and newly diagnosed prediabetic and T2DM patients. A total of 257 participants with NGT, newly diagnosed prediabetes or T2DM were recruited from Yinchao and Hangtian communities of Chengdu, Sichuan, China. Serum MANF level was quantified by enzyme-linked immunosorbent assay (ELISA). The mean age for the 257 participants (147 females) was 62±8 years (range 44-78): 71 with NGT, 115 with newly diagnosed prediabetes and 71 with T2DM. Mean serum MANF level was significantly higher with newly diagnosed prediabetes and T2DM than NGT (2.89±1.09 and 3.03±1.73 vs 2.13±1.37 ng/mL, both pprediabetes patients. We concluded that serum MANF level was higher in patients with newly diagnosed prediabetes and T2DM than in NGT controls. MANF appears to be associated with Matsuda Index, QUICKI and HOMA-IR in prediabetes patients.

  3. Localization of foot-and-mouth disease - RNA synthesis on newly formed cellular smooth membranous vacuoles

    International Nuclear Information System (INIS)

    Polatnick, J.; Wool, S.H.

    1982-01-01

    Viral RNA synthesis in foot-and-mouth disease infected bovine kidney cell cultures was associated throughout the infectious period with newly formed smooth membranous vacuoles. Membrane formation was measured by choline uptake. The site of RNA synthesis was determined by electron microscopic examination of autoradiograms of incorporated [ 3 H] uridine. Both membrane formation and RNA synthesis became signifcant at 2.5 hours postinfection, but membrane formation increased steadily to 4.5 hours while RNA synthesis peaked at 3.5 hours. Percent density distributions of developed silver grains on autoradiograms showed that almost all RNA synthesis was concentrated on the smooth vacuoles of infected cells. Histogram analysis of grain density distributions established that the site of RNA synthesis was the vacuolar membrane. The newly formed smooth membrane-bound vacuoles were not seen to coalesce into the large vacuolated areas typical of poliovirus cytopathogenicity. (Author)

  4. Localization of foot-and-mouth disease - RNA synthesis on newly formed cellular smooth membranous vacuoles

    Energy Technology Data Exchange (ETDEWEB)

    Polatnick, J.; Wool, S.H. (United States Department of Agriculture, Science and Education, Greenport, New York (USA). Agricultural Research, Plum Island Animal Disease Center)

    1982-01-01

    Viral RNA synthesis in foot-and-mouth disease infected bovine kidney cell cultures was associated throughout the infectious period with newly formed smooth membranous vacuoles. Membrane formation was measured by choline uptake. The site of RNA synthesis was determined by electron microscopic examination of autoradiograms of incorporated (/sup 3/H) uridine. Both membrane formation and RNA synthesis became signifcant at 2.5 hours postinfection, but membrane formation increased steadily to 4.5 hours while RNA synthesis peaked at 3.5 hours. Percent density distributions of developed silver grains on autoradiograms showed that almost all RNA synthesis was concentrated on the smooth vacuoles of infected cells. Histogram analysis of grain density distributions established that the site of RNA synthesis was the vacuolar membrane. The newly formed smooth membrane-bound vacuoles were not seen to coalesce into the large vacuolated areas typical of poliovirus cytopathogenicity.

  5. Clinical evaluation of a newly designed orthodontic tooth brush - A clinical study

    Directory of Open Access Journals (Sweden)

    C S Saimbi

    2009-01-01

    In this study, the newly designed orthodontic tooth brush is compared with an ordinary tooth brush. Results of this study show that the newly designed orthodontic tooth brush is superior in its cleaning efficiency as compared to the ordinary tooth brush. The results show that plaque removing capacity of orthodontic tooth brush is nearly 95-99%.

  6. Motional Stark Effect measurements of the local magnetic field in high temperature fusion plasmas

    Science.gov (United States)

    Wolf, R. C.; Bock, A.; Ford, O. P.; Reimer, R.; Burckhart, A.; Dinklage, A.; Hobirk, J.; Howard, J.; Reich, M.; Stober, J.

    2015-10-01

    The utilization of the Motional Stark Effect (MSE) experienced by the neutral hydrogen or deuterium injected into magnetically confined high temperature plasmas is a well established technique to infer the internal magnetic field distribution of fusion experiments. In their rest frame, the neutral atoms experience a Lorentz electric field, EL = v × B, which results in a characteristic line splitting and polarized line emission. The different properties of the Stark multiplet allow inferring, both the magnetic field strength and the orientation of the magnetic field vector. Besides recording the full MSE spectrum, several types of polarimeters have been developed to measure the polarization direction of the Stark line emission. To test physics models of the magnetic field distribution and dynamics, the accuracy requirements are quite demanding. In view of these requirements, the capabilities and issues of the different techniques are discussed, including the influence of the Zeeman Effect and the sensitivity to radial electric fields. A newly developed Imaging MSE system, which has been tested on the ASDEX Upgrade tokamak, is presented. The sensitivity allows to resolve sawtooth oscillations. A shorter version of this contribution is due to be published in PoS at: 1st EPS conference on Plasma Diagnostics

  7. Study on the system development for evaluating long-term alteration of hydraulic field in near field

    International Nuclear Information System (INIS)

    Okutu, Kazuo; Morikawa, Seiji; Takamura, Hisashi

    2002-02-01

    For the high performance evaluation of reliability of TRU waste repository, the system development for evaluating long-term alteration in consideration of the changes action of barrier materials of hydraulic field in Near Field is required. In this research, system development for evaluating long-term alteration of hydraulic field in Near Field was examined. Examination of the basic specification of chemical/dynamic alteration action analysis system used as the composition element of this system and a whole system were performed. The research result of this year is shown below. 1) The system by which the chemical changes happened by Near Field as influence of the exudation liquid from cement material are evaluated was examined. In this year, document investigation about the various processes about chemical alteration and extraction of a choice, presentation of the uncertainty about a model or data, preliminary modeling, a simple analysis tool creation and sensitivity analysis, extraction of the process which should be taken into consideration in a system valuation modeling and a phenomenon analysis model, and a corresponding mathematics model, optimization of the software composition for development of a system valuation modeling, the exercise by the preliminary system analysis model, the experiment plan for the corroboration of a model were shown. 2) In consideration of change of the physical characteristic accompanying chemical alteration of bentonite material and cement material, the system by which dynamic changes action of repository is evaluated was examined. In this year, arrangement of the dynamics action of repository for long-term were shown. Extraction of a phenomenon made applicable to evaluation was shown. And the dynamic models were investigated and the prototype of the dynamics model that can take into consideration the characteristic of bentonite material was shown. And the basic composition of a dynamic changes action analysis system was shown. 3

  8. Molecular and risk-based approach to nutrient development for a proposed sub-surface biogasification field trial in a biogenic gas field

    Energy Technology Data Exchange (ETDEWEB)

    Lambo, Adewale J.; Strapoc, Dariusz; Pittenger, Michelle; Huizinga, Bradley [ConocoPhillips (Canada); Wood, Ladonna; Ashby, Matt [Taxon Biosciences (Canada)

    2011-07-01

    This paper presents the molecular and risk-based approach to nutrient development for a proposed sub-surface biogasification field trial in a biogenic gas field. From field sampling, variability was seen in water chemistry and environmental parameters across the field; DNA yield also varied across the field and showed distinct spatial variation. The composition of microbial populations and relative distribution of archaea populations in the Cooks Inlet water is represented using pie and bar charts. The nutrient recipe was developed using known information on nutrient requirements of mathematically correlated microbial associations. The process of on-site nutrient injection is explained. Some of the mitigation plans for the risks involved during the process include, among others, limiting biofilm prevalence and avoiding bio-plugging and bio-corrosion. Biofilm is likely to develop in the injection line but less likely in nutrient mixing due to the high nutrient concentration. From the study, it can be concluded that community composition correlates with field geochemical parameters and methane pathways.

  9. A new methodology for minimizing investment in the development of offshore fields

    International Nuclear Information System (INIS)

    Garcia-Diaz, J.C.; Startzman, R.; Hogg, G.L.

    1996-01-01

    The development of an offshore field is often a long, complex, and extremely expensive undertaking. The enormous amount of capital required for making investments of this type motivates one to try to optimize the development of a field. This paper provides an efficient computational method to minimize the initial investment in the development of a field. The problem of minimizing the investment in an offshore field is defined here as the problem of locating a number of offshore facilities and wells and allocating these wells to the facilities at minimum cost. Side constraints include restrictions on the total number of facilities of every type and design and various technology constraints. This problem is modeled as a 0/1 integer program. The solution method is based on an implicit enumeration scheme using efficient mathematical tools, such as Lagrangian relaxation and heuristics, to calculate good bounds and, consequently, to reduce the computation time. The solution method was implemented and tested on some typical field-development cases. Execution times were remarkably small for the size and complexity of the examples. Computational results indicate that the new methodology outperforms existing methods both in execution time and in memory required

  10. Strategy of Gurgyan-Deniz field development

    International Nuclear Information System (INIS)

    Javadova, Rena A.; Gumbatov, Bahruz Y.

    2002-01-01

    Full text : It is known that during long suspension of oil-gas production process due to some reasons of technical and geological character through their further involvement into development one can observe restoration of productive characteristics of layers. it can be associated with redistribution of hydrodynamic flows, stratal pressure, segregation and other. Analysis of conducted geological, commercial-geophysical, geochemical results allowed to say about significant amount of residual reserves on the field. According to the obtained data distribution of residual oil reserves along horizons is presented in this article. In 2001 well which operates by gas lift method and gives production 25 ton/per day. In order to increase temp of selection and of course ratio of oil recovery after restoration of grid one should provide application of new methods of development.

  11. New developments in pulsed fields at the US National High Magnetic Field Laboratory

    International Nuclear Information System (INIS)

    Campbell, L.J.; Parkin, D.M.; Rickel, D.G.; Pernambuco-Wise, P.

    1996-01-01

    Los Alamos National Laboratory is a member of a consortium (with Florida State University and the University of Florida) to operate the National High Magnetic Field Laboratory (NHMFL), with funding from the National Science Foundation and the State of Florida. Los Alamos provides unique resources for its component of NHMFL in the form of a 1.4 GW inertial storage motor-generator for high field pulsed magnets and infrastructure for fields generated by flux compression. The NHMFL provides a user facility open to all qualified users, develops magnet technology in association with the private sector, and advances science and technology opportunities. The magnets in service at Los Alamos are of three types. Starting with the pre-existing explosive flux compression capability in 1991, NHMFL added capacitor-driven magnets in December, 1992, and a 20 tesla superconducting magnet in January, 1993. The capacitor-driven magnets continue to grow in diversity and accessibility, with four magnet stations now available for several different magnet types. Two magnets of unprecedented size and strength are nearing completion of assembly and design, respectively. Under final assembly is a quasi-continuous magnet that contains 90 MJ of magnetic energy at full field, and being designed is a non-destructive 100 T magnet containing 140 MJ

  12. Diabetes education improves depressive state in newly diagnosed patients with type 2 diabetes

    OpenAIRE

    Chen, Bin; Zhang, Xiyao; Xu, Xiuping; Lv, Xiaofeng; Yao, Lu; Huang, Xu; Guo, Xueying; Liu, Baozhu; Li, Qiang; Cui, Can

    2013-01-01

    Objectives: The prevalence of depression is relatively high in individuals with diabetes. However, screening and monitoring of depressive state in patients with diabetes is still neglected in developing countries and the treatment of diabetes-related depression is rarely performed in these countries. In this study, our aim was to study the role of diabetes education in the improvement of depressive state in newly diagnosed patients with type 2 diabetes. Methods: The Dutch version of the cente...

  13. Adult Education & Human Resource Development: Overlapping and Disparate Fields

    Science.gov (United States)

    Watkins, Karen E.; Marsick, Victoria J.

    2014-01-01

    Adult education and human resource development as fields of practice and study share some roots in common but have grown in different directions in their histories. Adult education's roots focused initially on citizenship for a democratic society, whereas human resource development's roots are in performance at work. While they have…

  14. Development of Spherical Near Field Model for Geological Radioactive Waste Repository

    International Nuclear Information System (INIS)

    Kim, S. Y.; Lee, K. J.; Chang, S. H.; Lee, K. J.; Chang, S. H.

    2012-01-01

    Modeling for geological radioactive waste repository can be divided into 3 parts. They are near field modeling related to engineered barrier, far field modeling related to natural barrier and biosphere modeling. In order to make the general application for safety assessment of geological waste repository, spherical geometry near field model has been developed. This model can be used quite extensively when users calculate equivalent spherical geometry for specific engineered barrier like equivalent waste radius, equivalent barrier radius and etc. Only diffusion was considered for general purpose but advection part can be updated. Goldsim and Goldsim Radionuclide Transport (RT) module were chosen and used as developing tool for the flexible modeling. Developer can freely make their own model with developer friendly graphic interface by using Goldsim. Furthermore, model with user friendly graphic interface can be developed by using Goldsim Dashboard Authoring module. The model has been validated by comparing the result with that of another model, inserting similar inputs and conditions. The model has been proved to be reasonably operating from the comparison result by validation process. Cylindrical model can be developed as a further work based on the knowledge and experience from this research

  15. Development of Spherical Near Field Model for Geological Radioactive Waste Repository

    Energy Technology Data Exchange (ETDEWEB)

    Kim, S. Y.; Lee, K. J.; Chang, S. H. [Korea Advanced Institute of Science and Technology, Daejeon (Korea, Republic of); Lee, K. J.; Chang, S. H. [Khalifa Univ. of Science/Technology and Research, Abu Dhabi (United Arab Emirates)

    2012-03-15

    Modeling for geological radioactive waste repository can be divided into 3 parts. They are near field modeling related to engineered barrier, far field modeling related to natural barrier and biosphere modeling. In order to make the general application for safety assessment of geological waste repository, spherical geometry near field model has been developed. This model can be used quite extensively when users calculate equivalent spherical geometry for specific engineered barrier like equivalent waste radius, equivalent barrier radius and etc. Only diffusion was considered for general purpose but advection part can be updated. Goldsim and Goldsim Radionuclide Transport (RT) module were chosen and used as developing tool for the flexible modeling. Developer can freely make their own model with developer friendly graphic interface by using Goldsim. Furthermore, model with user friendly graphic interface can be developed by using Goldsim Dashboard Authoring module. The model has been validated by comparing the result with that of another model, inserting similar inputs and conditions. The model has been proved to be reasonably operating from the comparison result by validation process. Cylindrical model can be developed as a further work based on the knowledge and experience from this research.

  16. Newly elected IAEA Board of Governors

    International Nuclear Information System (INIS)

    2001-01-01

    The document gives information about the election of 11 Member States to the IAEA Board of Governors, the 35-member policy-making body, during the 45th regular session of the IAEA's General Conference (17-21 September 2001, Austria Center, Vienna). The newly elected Member States are: Bulgaria, Burkina Faso, Chile, Colombia, Islamic Republic of Iran, Kuwait, Morocco, Philippines, Romania, Spain, and Turkey. The other 24 Member States of the Board are also given

  17. Health problems of newly arrived migrants and refugees in Europe.

    Science.gov (United States)

    Pavli, Androula; Maltezou, Helena

    2017-07-01

    The number of migrants and refugees in Europe in the past few years has increased dramatically due to war, violence or prosecutions in their homeland. Migration may affect physical, mental and social health. The objective of this article is to assess migrants and refugees' health problems, and to recommend appropriate interventions. A PubMed search of published articles on health problems of newly arrived migrants and refugees was conducted from 2003 through 2016, focusing on the current refugee crisis in Europe. In addition to communicable diseases, such as respiratory, gastrointestinal and dermatologic infections, non-communicable diseases, including chronic conditions, mental and social problems, account for a significant morbidity burden in newly arrived migrants and refugees. Vaccine-preventable diseases are also of outmost importance. The appropriate management of newly arrived refugees and migrants' health problems is affected by barriers to access to health care including legal, communication, cultural and bureaucratic difficulties. There is diversity and lack of integration regarding health care provision across Europe due to policy differences between health care systems and social services. There is a notable burden of communicable and non-communicable diseases among newly arrived migrants and refugees. Provision of health care at reception and temporary centres should be integrated and provided by a multidisciplinary team Appropriate health care of migrants and refugees could greatly enhance their health and social status which will benefit also the host countries at large. © International Society of Travel Medicine, 2017. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

  18. Vortex rings and jets recent developments in near-field dynamics

    CERN Document Server

    Yu, Simon

    2015-01-01

    In this book, recent developments in our understanding of fundamental vortex ring and jet dynamics will be discussed, with a view to shed light upon their near-field behaviour which underpins much of their far-field characteristics. The chapters provide up-to-date research findings by their respective experts and seek to link near-field flow physics of vortex ring and jet flows with end-applications in mind. Over the past decade, our knowledge on vortex ring and jet flows has grown by leaps and bounds, thanks to increasing use of high-fidelity, high-accuracy experimental techniques and numerical simulations. As such, we now have a much better appreciation and understanding on the initiation and near-field developments of vortex ring and jet flows under many varied initial and boundary conditions. Chapter 1 outlines the vortex ring pinch-off phenomenon and how it relates to the initial stages of jet formations and subsequent jet behaviour, while Chapter 2 takes a closer look at the behaviour resulting from vor...

  19. Educational Investments and Economic Development: A Field Study.

    Science.gov (United States)

    Champaigne, John

    A study examined the relationship between educational investments and economic development in the small community of Canandaigua, New York. A field study approach was used to collect data pertaining to the city's population characteristics, income characteristics, economic conditions, unemployment rates, and housing conditions. These data were…

  20. Modeling of Local Magnetic Field Enhancements within Solar Flux Ropes

    OpenAIRE

    Romashets, E; Vandas, M; Poedts, Stefaan

    2010-01-01

    To model and study local magnetic-field enhancements in a solar flux rope we consider the magnetic field in its interior as a superposition of two linear (constant alpha) force-free magnetic-field distributions, viz. a global one, which is locally similar to a part of the cylinder, and a local torus-shaped magnetic distribution. The newly derived solution for a toroid with an aspect ratio close to unity is applied. The symmetry axis of the toroid and that of the cylinder may or may not coinci...

  1. Real options and volume uncertainty by field development projects

    International Nuclear Information System (INIS)

    Ekern, S.; Stensland, G.

    1993-12-01

    The report concerns a study on the use of option methodology in field development projects. The report shows how the value of flexibility in the different decision processes is to be found by means of real option methodology. Particular attention is laid on the uncertainty concerning the volume of reserves and production capacity. The results from the study were based on the research project dubbed ''Use of real options in field development projects''. The project is partially connected to another project dubbed ''Decisive behaviour and alternative action under uncertainty in the petroleum sector''. Main topics cover as follow: Example with volume uncertainty; real options and volume uncertainty; gradual disclosure of uncertainty in the production; value of flexible production equipment. 33 refs., 19 figs., 17 tabs

  2. Methodology for oil field development; Metodologia para o desenvolvimento de campos de petroleo

    Energy Technology Data Exchange (ETDEWEB)

    Galeano, Yadira Diaz

    1998-07-01

    The main scope of this work is to study and develop a methodology which allows the elaboration of project for oil field development. There fore it is necessary to consider to consider the integration of the human, technological and economical issues that are important parameters in the engineering project. The spiral concept was applied for the project in order to coordinate, in a reasonable and logical way, the activities involved in the field development, as well as the hierarchical analysis method for the decision making process. The development of an oil field is divided in viability study, preliminary project, final project, project implementation, production and field abandonment cycles. The main components for each cycle are external aspects, environmental criteria, reservoir management, and drilling, completion and well workover, production systems, exportation systems, and risk and economical analysis. The proposed methodology establishes a general scheme for planning and it presents applicable procedures for any field. (author)

  3. Histological evaluation of tissue reactions to newly synthetized calcium silicate- and hydroxyapatite-based bioactive materials: in vivo study

    Directory of Open Access Journals (Sweden)

    Opačić-Galić Vanja

    2017-01-01

    Full Text Available Introduction/Objective. Development of materials which could be used as biological bone substitutes is one of the most valuable and active fields of biomaterial research. The goal of the study was to research the reaction of tissue on calcium silicate- (CS and hydroxyapatitebased (CS-HA newly synthesized nanomaterials, after being implanted into the subcutaneous tissue of a rats and direct pulp capping of rabbit teeth. Methods. The tested materials were implanted in 40 Wistar male rats, sacrificed after seven, 15, 30, and 60 days. The direct pulp capping was performed on the teeth of rabbits. Cavities were prepared on the vestibular surface of the incisors. The animals were sacrificed after 10 and 15 days. The control material was mineral trioxide aggregate (MTA. Histological analysis covered the tracking of inflammatory reaction cellular components, presence of gigantic cells, and necrosis of the tissue. Results. Seven days after the implantation, the strongest inflammatory response was given by the MTA (3.3 Ѓ} 0.48, while CS and CS-HA scored 3 ± 0.71. After 60 days, the rate of inflammatory reactions dropped, which was the least visible with CS-HA (0.2 ± 0.45. The least visible inflammatory reaction of the rabbits’ pulp tissue was spotted with the CS (1.83 ± 0.75, than with the MTA and CS-HA (2.67 ± 1.53, 3 ± 0.63. Conclusion. The newly synthesized materials caused a slight reaction of the subcutaneous tissue. CS-HA showed the best tissue tolerance. Nanostructural biomaterials caused a slight to moderate inflammatory reaction of the rabbits’ pulp tissue only in the immediate vicinity of the implanted material.

  4. Evidos: optimisation of individual monitoring in mixed neutron/photon fields at workplaces of the nuclear fuel cycle

    International Nuclear Information System (INIS)

    Luszik-Bhadra, M.; Reginatto, M.; Schuhmacher, H.; Lacoste, V.; Muller, M.; Boschung, M.; Fiechtner, A.; Coeck, M.; Vanhavere, F.; Curzio, G.; D'errico, F.; Kyllonen, J.E.; Lindborg, L.; Molinos, C.; Tanner, R.; Derdau, D.; Lahaye, Th.

    2005-01-01

    Within its 5. Framework Programme, the EC is funding the project EVIDOS ('Evaluation of Individual Dosimetry in Mixed Neutron and Photon Radiation Fields'). The aim of this project is the optimisation of individual monitoring at workplaces of the nuclear fuel cycle with special regard to neutrons. Various dosemeters for mixed field application - passive and new electronic devices - are tested in selected workplace fields in nuclear installations in Europe. The fields are characterised using a series of spectrometers that provide the energy distribution of neutron fluence (Bonner spheres) and newly developed devices that provide the energy and directional distribution of the neutron fluence. Results from the first measurement campaign, carried out in simulated workplace fields (IRSN, Cadarache. France), and those of a second measurement campaign, carried out at workplaces at a boiling water reactor and at a storage cask with used fuel elements (Kernkraftwerk Kriimmel, Germany), are described. (authors)

  5. Enhancement of Treatment Efficiency of Recalcitrant Wastewater Containing Textile Dyes Using a Newly Developed Iron Zeolite Socony Mobil-5 Heterogeneous Catalyst

    Science.gov (United States)

    Ahmad, Mushtaq; Asghar, Anam; Abdul Raman, Abdul Aziz; Wan Daud, Wan Mohd Ashri

    2015-01-01

    Fenton oxidation, an advanced oxidation process, is an efficient method for the treatment of recalcitrant wastewaters. Unfortunately, it utilizes H2O2 and iron-based homogeneous catalysts, which lead to the formation of high volumes of sludge and secondary pollutants. To overcome these problems, an alternate option is the usage of heterogeneous catalyst. In this study, a heterogeneous catalyst was developed to provide an alternative solution for homogeneous Fenton oxidation. Iron Zeolite Socony Mobile-5 (Fe-ZSM-5) was synthesized using a new two-step process. Next, the catalyst was characterized by scanning electron microscopy, energy-dispersive X-ray spectroscopy, fourier transform infrared spectroscopy, and Brunauer-Emmett-Teller analysis and tested against a model wastewater containing the azo dye Acid Blue 113. Results showed that the loading of iron particles reduced the surface area of the catalyst from 293.59 to 243.93 m2/g; meanwhile, the average particle size of the loaded material was 12.29 nm. Furthermore, efficiency of the developed catalyst was evaluated by performing heterogeneous Fenton oxidation. Taguchi method was coupled with principal component analysis in order to assess and optimize mineralization efficiency. Experimental results showed that under optimized conditions, over 99.7% degradation and 77% mineralization was obtained, with a 90% reduction in the consumption of the developed catalyst. Furthermore, the developed catalyst was stable and reusable, with less than 2% leaching observed under optimized conditions. Thus, the present study proved that newly developed catalyst has enhanced the oxidation process and reduced the chemicals consumption. PMID:26517827

  6. Enhancement of Treatment Efficiency of Recalcitrant Wastewater Containing Textile Dyes Using a Newly Developed Iron Zeolite Socony Mobil-5 Heterogeneous Catalyst.

    Science.gov (United States)

    Ahmad, Mushtaq; Asghar, Anam; Abdul Raman, Abdul Aziz; Wan Daud, Wan Mohd Ashri

    2015-01-01

    Fenton oxidation, an advanced oxidation process, is an efficient method for the treatment of recalcitrant wastewaters. Unfortunately, it utilizes H2O2 and iron-based homogeneous catalysts, which lead to the formation of high volumes of sludge and secondary pollutants. To overcome these problems, an alternate option is the usage of heterogeneous catalyst. In this study, a heterogeneous catalyst was developed to provide an alternative solution for homogeneous Fenton oxidation. Iron Zeolite Socony Mobile-5 (Fe-ZSM-5) was synthesized using a new two-step process. Next, the catalyst was characterized by scanning electron microscopy, energy-dispersive X-ray spectroscopy, fourier transform infrared spectroscopy, and Brunauer-Emmett-Teller analysis and tested against a model wastewater containing the azo dye Acid Blue 113. Results showed that the loading of iron particles reduced the surface area of the catalyst from 293.59 to 243.93 m2/g; meanwhile, the average particle size of the loaded material was 12.29 nm. Furthermore, efficiency of the developed catalyst was evaluated by performing heterogeneous Fenton oxidation. Taguchi method was coupled with principal component analysis in order to assess and optimize mineralization efficiency. Experimental results showed that under optimized conditions, over 99.7% degradation and 77% mineralization was obtained, with a 90% reduction in the consumption of the developed catalyst. Furthermore, the developed catalyst was stable and reusable, with less than 2% leaching observed under optimized conditions. Thus, the present study proved that newly developed catalyst has enhanced the oxidation process and reduced the chemicals consumption.

  7. Economies: An Open Access Journal for the Field of Development Macroeconomics

    Directory of Open Access Journals (Sweden)

    Ralf Fendel

    2013-01-01

    Full Text Available Economies (ISSN 2227-7099 is a new international, peer-reviewed open access journal for the academic fields of development economics and macroeconomics. While the latter seems to be clearly defined, development economics is not, because it is related to nearly all traditional economic sub-disciplines such as macroeconomics, international trade and finance, as well as microeconomics and public finance. Typically, academic field journals of development economics cover all those economic sub-disciplines. Economies instead focuses mainly on the macroeconomic perspective of economic development and it intends to publish academic research that is of strong macroeconomic policy relevance. In general, contributions in Economies should foster understanding of the macroeconomic process of economic development, with the process of development not exclusively being reserved to what we typically call developing countries. Also, the group of developed economies is still developing in the sense of improving their living standards further.

  8. Indian gas field development plan aims for quick production

    International Nuclear Information System (INIS)

    Banerjee, N.

    1992-01-01

    The development of a new oil or gas field involves construction of various downstream facilities such as field flow lines, trunk lines, oil and gas collecting and processing stations, and transportation to refineries and consuming centers. This paper reports that it is essential that these facilities be built on a schedule that allows the products to be transported and processed as early as possible. Unless such an approach is initiated, the wells producing crude oil or natural gas will need to be shut-in in the absence of the other relative facilities. For quick returns on the investments, a realistic program and careful evaluation of the schedule is needed to ensure that early commissioning of the fields is possible

  9. Development of a reactive force field for iron-oxyhydroxide systems.

    Science.gov (United States)

    Aryanpour, Masoud; van Duin, Adri C T; Kubicki, James D

    2010-06-03

    We adopt a classical force field methodology, ReaxFF, which is able to reproduce chemical reactions, and train its parameters for the thermodynamics of iron oxides as well as energetics of a few iron redox reactions. Two parametrizations are developed, and their results are compared with quantum calculations or experimental measurements. In addition to training, two test cases are considered: the lattice parameters of a selected set of iron minerals, and the molecular dynamics simulation of a model for alpha-FeOOH (goethite)-water interaction. Reliability and limitations of the developed force fields in predicting structure and energetics are discussed.

  10. Disciplines in the field of communication for development and social change

    NARCIS (Netherlands)

    Lie, R.; Servaes, J.

    2015-01-01

    This article provides an overview of subdisciplines in the field of Communication for Development and Social Change. Different subdisciplines of communication science are analyzed to assess their connection to the field. Building on these subdisciplines the article reviews health communication,

  11. The effects of pseudo magnetic fields in molecular spectra and scattering

    International Nuclear Information System (INIS)

    Kendrick, B.K.

    1996-01-01

    Pseudo magnetic fields appear in the Born-Oppenheimer method for molecules when conical intersections or electronic angular momenta are taken into account. These fields are not real magnetic fields but they have the same mathematical properties and can lead to real observable effects in the dynamics of molecules. A general vector potential (gauge theory) approach for including these field effects in the Born-Oppenheimer method is introduced and applied to H + O 2 scattering and the vibrational spectrum of Na 3 (X) for zero total angular momentum (J = 0). The scattering results for HO 2 show significant shifts in the resonance energies and lifetimes due to a magnetic solenoid type field originating from the C 2v conical intersection in HO 2 . Significant changes in the state-to-state transition probabilities are also observed. The non-degenerate A 1 and A 2 vibrational spectra of Na 3 (X) show significant shifts in the energy levels due to a magnetic solenoid type field originating from the D 3h conical intersection in Na 3 . These two examples show that the effects of pseudo magnetic fields can be significant and in many cases they must be included in order to obtain agreement between theory and experiment. The newly developed gauge theory techniques for treating pseudo magnetic fields are also relevant for including the effects of real magnetic fields

  12. The vacuum structure, special relativity theory and quantum mechanics revisited: a field theory-no-geometry approach

    International Nuclear Information System (INIS)

    Bogolubov, N.N. Jr.; Prykarpatsky, A.K.; Ufuk Taneri

    2008-07-01

    The main fundamental principles characterizing the vacuum field structure are formulated and the modeling of the related vacuum medium and charged point particle dynamics by means of de- vised field theoretic tools are analyzed. The Maxwell electrodynamic theory is revisited and newly derived from the suggested vacuum field structure principles and the classical special relativity theory relationship between the energy and the corresponding point particle mass is revisited and newly obtained. The Lorentz force expression with respect to arbitrary non-inertial reference frames is revisited and discussed in detail, and some new interpretations of relations between the special relativity theory and quantum mechanics are presented. The famous quantum-mechanical Schroedinger type equations for a relativistic point particle in the external potential and magnetic fields within the quasiclassical approximation as the Planck constant (h/2π) → 0 and the light velocity c → ∞ are obtained. (author)

  13. Radiation therapy of newly diagnosed, advanced prostatic cancer and hormonally relapsed prostatic cancer

    International Nuclear Information System (INIS)

    Suzuki, Minoru; Fujiwara, Kazuhisa; Hayakawa, Katsumi; Hida, Shuichi

    1994-01-01

    Ten patients with newly diagnosed, advanced prostatic cancer were treated with radiotherapy and hormone therapy to improve tumor control and survival. Eight patients with hormonally relapsed prostatic cancer were treated with radiotherapy to improve their quality of life. Local control of the tumor was achieved in 9 of 10 patients with newly diagnosed, advanced prostatic cancer. Five of eight patients with hormonally relapsed prostatic cancer obtained improved quality of life. Combined radiotherapy and hormone therapy were effective in the treatment of newly diagnosed, advanced prostatic cancer, and radiotherapy was useful for improving the quality of life of patients with hormonally relapsed prostatic cancer. (author)

  14. Three Newly Naturalized Plants in Taiwan

    Directory of Open Access Journals (Sweden)

    Ming-Jer Jung

    2009-11-01

    Full Text Available Three newly naturalized plants are reported in this paper. Hypochaeris microcephala (Sch. Bip. Cabrera var. albiflora (Kuntze Cabrera (Asteraceae is naturalized in urban areas of northern Taiwan. Indigofera pseudo-tinctoria Matsum. (Leguminosae is naturalized in low elevations of northern and southern Taiwan and in middle elevations of central Taiwan. Lamium purpureum L. (Laminaceae has become naturalized locally in middle elevations of central Taiwan. Descriptions, illustrations and color photos of these plants are provided.

  15. Successful talent development in track and field

    DEFF Research Database (Denmark)

    Henriksen, K; Stambulova, N; Roessler, K K

    2010-01-01

    Track and field includes a number of high-intensity disciplines with many demanding practices and represents a motivational challenge for talented athletes aiming to make a successful transition to the senior elite level. Based on a holistic ecological approach, this study presents an analysis...... of a particular athletic talent development environment, the IFK Växjö track and field club, and examines key factors behind its successful history of creating top-level athletes. The research takes the form of a case study. Data were collected from multiple perspectives (in-depth interviews with administrators...... to elite athletes. A strong organizational culture, characterized by values of open co-operation, by a focus on performance process and by a whole-person approach, provided an important basis for the environment's success. The holistic ecological approach encourages practitioners to broaden their focus...

  16. A Newly Developed Perfused Umbrella Electrode for Radiofrequency Ablation: An Ex Vivo Evaluation Study in Bovine Liver

    International Nuclear Information System (INIS)

    Bruners, Philipp; Pfeffer, Jochen; Kazim, Rana M.; Guenther, Rolf W.; Schmitz-Rode, Thomas; Mahnken, Andreas H.

    2007-01-01

    The purpose of this study was to evaluate the effectiveness of a newly developed perfused monopolar radiofrequency (RF) probe with an umbrella-shaped array. A perfused umbrella-shaped monopolar RF probe based on a LeVeen electrode (Boston Scientific Corp., Natick, MA, USA) with a 3-cm array diameter was developed. Five different configurations of this electrode were tested: (a) perfusion channel/endhole, (b) perfusion channel/endhole + sideholes, (c) 1 cm insulation removed at the tip, (d) 1 cm insulation removed at the tip + perfusion channel/endhole, and (e) 1 cm insulation removed at the tip + perfusion channel/endhole + sideholes. An unmodified LeVeen electrode served as a reference standard. RF ablations were performed in freshly excised bovine liver using a commercial monopolar RF system with a 200-W generator (RF 3000; Boston Scientific Corp.). Each electrode was tested 10 times applying the vendor's recommended ablation protocol combined with the preinjection of 2 ml 0.9% saline. Volumes and shapes of the lesions were compared. Lesions generated with the original LeVeen electrode showed a mean volume of 12.74 ± 0.52 cm 3 . Removing parts of the insulation led to larger coagulation volumes (22.65 ± 2.12 cm 3 ). Depending on the configuration, saline preinjection resulted in a further increase in coagulation volume (25.22 ± 3.37 to 31.28 ± 2.32 cm 3 ). Besides lesion volume, the shape of the ablation zone was influenced by the configuration of the electrode used. We conclude that saline preinjection in combination with increasing the active tip length of the umbrella-shaped LeVeen RF probe allows the reliable ablation of larger volumes in comparison to the originally configured electrode

  17. Heat pumps in field test; Waermepumpen im Feldtest

    Energy Technology Data Exchange (ETDEWEB)

    Becker, R. [Fraunhofer-Institut fuer Solare Energiesysteme (ISE), Freiburg im Breisgau (Germany); Miara, M.; Russ, C.

    2007-09-15

    The Fraunhofer ISE has launched two field tests of newly installed heat pumps in 2006. Both deal with the measurement of a high number of heat pump units under real conditions in small houses. Values of volume flows, temperatures, heat quantity and electricity consumption are collected and daily saved and analysed at the Fraunhofer ISE. (orig.)

  18. Assessment of a Newly Developed, Active Pneumatic-Driven, Sensorimotor Test and Training Device

    Directory of Open Access Journals (Sweden)

    Wolfram Haslinger

    2014-12-01

    Full Text Available The sensorimotor system (SMS plays an important role in sports and in every day movement. Several tools for assessment and training have been designed. Many of them are directed to specific populations, and have major shortcomings due to the training effect or safety. The aim of the present study was to design and assess a dynamic sensorimotor test and training device that can be adjusted for all levels of performance. The novel pneumatic-driven mechatronic device can guide the trainee, allow independent movements or disrupt the individual with unpredicted perturbations while standing on a platform. The test-reliability was evaluated using intraclass correlation coefficient (ICC. Subjects were required to balance their center of pressure (COP in a target circle (TITC. The time in TITC and the COP error (COPe were recorded for analysis. The results of 22 males and 14 females (23.7 ± 2.6 years showed good to excellent test–retest reliability. The newly designed Active Balance System (ABS was then compared with the Biodex Balance System SD® (BBS. The results of 15 females, 14 males (23.4 ± 1.6 years showed modest correlation in static and acceptable correlation in dynamic conditions, suggesting that ABS could be a reliable and comparable tool for dynamic balance assessments.

  19. Development of mean field theories in nuclear physics and in desordered media

    International Nuclear Information System (INIS)

    Orland, Henri.

    1981-04-01

    This work, in two parts, deals with the development of mean field theories in nuclear physics (nuclei in balance and collisions of heavy ions) as well as in disordered media. In the first part, two different ways of tackling the problem of developments around mean field theories are explained. Possessing an approach wave function for the system, the natural idea for including the correlations is to develop the exact wave function of the system around the mean field wave function. The first two chapters show two different ways of dealing with this problem: the perturbative approach - Hartree-Fock equations with two body collisions and functional methods. In the second part: mean field theory for spin glasses. The problem for spin glasses is to construct a physically acceptable mean field theory. The importance of this problem in statistical mechanics is linked to the fact that the mean field theory provides a qualitative description of the low temperature phase and is the starting point needed for using more sophisticated methods (renormalization group). Two approaches to this problem are presented, one based on the Sherrington-Kirkpatrick model and the other based on a model of spins with purely local disorder and competitive interaction between the spins [fr

  20. Weathering model in paleomagnetic field intensity measurements on ancient fired clays

    International Nuclear Information System (INIS)

    Singalas, I.; Gangas, N-H.J.; Danon, J.

    1978-03-01

    Nonlinearities observed in Thellier's plots are explained in terms of a weathering model. This model is based on the reduction in size of the originaly present iron oxide particles, due to leaching. In the general case, the slope of the Thellier's plot is a function of the particle size destributions of the magnetic particles, both newly formed and leached ones. In the special case in which the newly formed magnetic particles are superparamagnetic, the limiting value of the slope of th Thellier's plot towards the magnetic ordering temperature is equal to the ratio of the ancient field intensity to the modern one

  1. Health Coaching: A Developing Field within Health Education

    Science.gov (United States)

    Palmer, Stephen

    2004-01-01

    The health promotion and health education literature has references to health counselling. Yet, beyond the field of health, coaching has become a popular method to enhance and facilitate individual and group performance in business, sports, and personal areas of life. This paper focuses on the recent development of health coaching by practitioners…

  2. Laser Nitriding of the Newly Developed Ti-20Nb-13Zr at.% Biomaterial Alloy to Enhance Its Mechanical and Corrosion Properties in Simulated Body Fluid

    Science.gov (United States)

    Hussein, M. A.; Kumar, A. Madhan; Yilbas, Bekir S.; Al-Aqeeli, N.

    2017-11-01

    Despite the widespread application of Ti alloy in the biomedical field, surface treatments are typically applied to improve its resistance to corrosion and wear. A newly developed biomedical Ti-20Nb-13Zr at.% alloy (TNZ) was laser-treated in nitrogen environment to improve its surface characteristics with corrosion protection performance. Surface modification of the alloy by laser was performed through a Nd:YAG laser. The structural and surface morphological alterations in the laser nitrided layer were investigated by XRD and a FE-SEM. The mechanical properties have been evaluated using nanoindentation for laser nitride and as-received samples. The corrosion protection behavior was estimated using electrochemical corrosion analysis in a physiological medium (SBF). The obtained results revealed the production of a dense and compact film of TiN fine grains (micro-/nanosize) with 9.1 µm below the surface. The mechanical assessment results indicated an improvement in the modulus of elasticity, hardness, and resistance of the formed TiN layer to plastic deformation. The electrochemical analysis exhibited that the surface protection performance of the laser nitrided TNZ substrates in the SBF could be considerably enhanced compared to that of the as-received alloy due to the presence of fine grains in the TiN layer resulting from laser nitriding. Furthermore, the untreated and treated Ti-20Nb-13Zr alloy exhibited higher corrosion resistance than the CpTi and Ti6Al4V commercial alloys. The improvements in the surface hardness and corrosion properties of Ti alloy in a simulated body obtained using laser nitriding make this approach a suitable candidate for enhancing the properties of biomaterials.

  3. Field application of smart SHM using field programmable gate array technology to monitor an RC bridge in New Mexico

    International Nuclear Information System (INIS)

    Azarbayejani, M; Jalalpour, M; Reda Taha, M M; El-Osery, A I

    2011-01-01

    In this paper, an innovative field application of a structural health monitoring (SHM) system using field programmable gate array (FPGA) technology and wireless communication is presented. The new SHM system was installed to monitor a reinforced concrete (RC) bridge on Interstate 40 (I-40) in Tucumcari, New Mexico. This newly installed system allows continuous remote monitoring of this bridge using solar power. Details of the SHM component design and installation are discussed. The integration of FPGA and solar power technologies make it possible to remotely monitor infrastructure with limited access to power. Furthermore, the use of FPGA technology enables smart monitoring where data communication takes place on-need (when damage warning signs are met) and on-demand for periodic monitoring of the bridge. Such a system enables a significant cut in communication cost and power demands which are two challenges during SHM operation. Finally, a three-dimensional finite element (FE) model of the bridge was developed and calibrated using a static loading field test. This model is then used for simulating damage occurrence on the bridge. Using the proposed automation process for SHM will reduce human intervention significantly and can save millions of dollars currently spent on prescheduled inspection of critical infrastructure worldwide

  4. Field application of smart SHM using field programmable gate array technology to monitor an RC bridge in New Mexico

    Science.gov (United States)

    Azarbayejani, M.; Jalalpour, M.; El-Osery, A. I.; Reda Taha, M. M.

    2011-08-01

    In this paper, an innovative field application of a structural health monitoring (SHM) system using field programmable gate array (FPGA) technology and wireless communication is presented. The new SHM system was installed to monitor a reinforced concrete (RC) bridge on Interstate 40 (I-40) in Tucumcari, New Mexico. This newly installed system allows continuous remote monitoring of this bridge using solar power. Details of the SHM component design and installation are discussed. The integration of FPGA and solar power technologies make it possible to remotely monitor infrastructure with limited access to power. Furthermore, the use of FPGA technology enables smart monitoring where data communication takes place on-need (when damage warning signs are met) and on-demand for periodic monitoring of the bridge. Such a system enables a significant cut in communication cost and power demands which are two challenges during SHM operation. Finally, a three-dimensional finite element (FE) model of the bridge was developed and calibrated using a static loading field test. This model is then used for simulating damage occurrence on the bridge. Using the proposed automation process for SHM will reduce human intervention significantly and can save millions of dollars currently spent on prescheduled inspection of critical infrastructure worldwide.

  5. Validation of mentorship model for newly qualified professional ...

    African Journals Online (AJOL)

    Newly qualified professional nurses (NQPNs) allocated to community health care services require the use of validated model to practice independently. Validation was done to adapt and assess if the model is understood and could be implemented by NQPNs and mentors employed in community health care services.

  6. The North Field Development

    International Nuclear Information System (INIS)

    1993-01-01

    The Qatar Europe LNG Company's activities include gas production, gathering, treatment, liquefaction, shipping and marketing of Liquefied Natural Gas (LNG) and by-products. The (LNG) project to be developed by the Company shall be initially capable of processing 1200 mmscfd of raw gas and associated quantities of condensate from the North Field. Hydrocarbons produced will be delivered to shore in the industrial area (Ras Laffan) via a sub sea pipeline system. Raw gas is used as a feedstock into the liquefaction plant which is initially capable of producing 6.1 Million Tonnes Per Annum (MTPA) of (LNG). The initial quantity of (LNG) will be exported from (Ras Laffan) loading terminal to a receiving terminal located on the North East coast of Italy via a dedicated fleet of (LNG) carriers. The whole project (Upstream, Downstream and Shipping) shall be executed on an integrated scheme basis under the the direct control of the Qatar Europe LNG Company and in accordance with the overall Master Schedule in order to ensure a delivery of first shipment of (LNG) in the 2 nd half of 1997. 3 figs

  7. Development of training courses in the field of nuclear energy

    International Nuclear Information System (INIS)

    Lee, Han Young; Seo, In Seok; Lee, Eui Jin; Seo, Kyung Won; Won, Jong Yeol; Nam, Jae Yeol

    1996-02-01

    This report describes the final results of D evelopment of training courses in the field of nuclear energy . The scope and contents are as follows : 1. to develop specialized nuclear training programs. 2. to collect and analyze foreign training programs and materials. 3. to develop foreign assisted training courses. 4. to develop interregional training courses for developing country trainees. and 5. to develop text materials for the implementation of training courses. 16 refs. (Author)

  8. Three New Records of Ascomycetes Isolates from Field Soils in Korea

    OpenAIRE

    Adhikari, Mahesh; Gurung, Sun Kumar; Kim, Hyun Seung; Bazie, Setu; Lee, Hyun Gu; Lee, Hyang Burm; Lee, Youn Su

    2017-01-01

    Three new records of Ascomycota species (Chaetomium acropullum, Phialemonium globosum, Phialemonium atrogriseum) from field soils in Korea are presented in this study. These newly discovered fungal isolates were isolated from field soils from various places across Gyeongnam, Korea in 2016. All the isolates were identified and described based on morphological characteristics, and rDNA internal transcribed spacer and β-tubulin gene sequence data. Morphological features of these fungal species w...

  9. Architecture and Development of DCMP Web Site

    Science.gov (United States)

    Bariakhtar, Irina

    2003-03-01

    The multi-tier implementation of DCMP Web site is discussed. It is based upon newly developed PHP technology. The technology allows for creating dynamic content and scalable solutions for Web site capabilities. There are several aspects as to what type of information is to be on the site. First, it should serve the immediate needs of the researchers in the field, namely, conferences, journals, news, funds, etc. This is currently available on the site, but can be extended and improved if needed. Second, the site will reflect the connection between Condensed matter physics and the technological breakthroughs that drive the economy. Third, the site will carry an educational mission helping educate the general public, and on the other hand, help young people to start their careers in the field. The content of the DCMP Web site is under active development. It depends upon wide involvement of DCMP members.

  10. Newly divided eosinophils limit ozone-induced airway hyperreactivity in nonsensitized guinea pigs.

    Science.gov (United States)

    Wicher, Sarah A; Jacoby, David B; Fryer, Allison D

    2017-06-01

    Ozone causes vagally mediated airway hyperreactivity and recruits inflammatory cells, including eosinophils, to lungs, where they mediate ozone-induced hyperreactivity 1 day after exposure but are paradoxically protective 3 days later. We aimed to test the role of newly divided eosinophils in ozone-induced airway hyperreactivity in sensitized and nonsensitized guinea pigs. Nonsensitized and sensitized guinea pigs were treated with 5-bromo-2-deoxyuridine (BrdU) to label newly divided cells and were exposed to air or ozone for 4 h. Later (1 or 3 days later), vagally induced bronchoconstriction was measured, and inflammatory cells were harvested from bone marrow, blood, and bronchoalveolar lavage. Ozone induced eosinophil hematopoiesis. One day after ozone, mature eosinophils dominate the inflammatory response and potentiate vagally induced bronchoconstriction. However, by 3 days, newly divided eosinophils have reached the lungs, where they inhibit ozone-induced airway hyperreactivity because depleting them with antibody to IL-5 or a TNF-α antagonist worsened vagally induced bronchoconstriction. In sensitized guinea pigs, both ozone-induced eosinophil hematopoiesis and subsequent recruitment of newly divided eosinophils to lungs 3 days later failed to occur. Thus mature eosinophils dominated the ozone-induced inflammatory response in sensitized guinea pigs. Depleting these mature eosinophils prevented ozone-induced airway hyperreactivity in sensitized animals. Ozone induces eosinophil hematopoiesis and recruitment to lungs, where 3 days later, newly divided eosinophils attenuate vagally mediated hyperreactivity. Ozone-induced hematopoiesis of beneficial eosinophils is blocked by a TNF-α antagonist or by prior sensitization. In these animals, mature eosinophils are associated with hyperreactivity. Thus interventions targeting eosinophils, although beneficial in atopic individuals, may delay resolution of airway hyperreactivity in nonatopic individuals. Copyright

  11. Examination of in vivo gelatinolytic activity in rheumatoid arthritis synovial tissue using newly developed in situ zymography and image analyzer.

    Science.gov (United States)

    Yoshida, W; Uzuki, M; Nishida, J; Shimamura, T; Sawai, T

    2009-01-01

    The aim of this study was to examine in vivo gelatinolytic activity of rheumatoid arthritis (RA) synovium using a newly developed in situ zymography (ISZ) method and pathological image analyzer, and to evaluate the relationship between this activity and several features on RA. A total of 8 samples of synovium were obtained from RA patients during surgery, and 8 samples from osteoarthritis (OA) patients were examined as controls. Furthermore, total 14 samples of syovium were obtained for comparison among radiographical classifications as Larsen grade (4 cases of grade III, 5 cases of grade IV and 5 cases of grade V). These specimens were frozen with OCT compound immediately after surgery. Frozen sections were applied to a newly developed gelatin-coated FIZ film (Fuji Film Co.Tokyo.Japan) designed for use ISZ, and incubated at 37 degrees C for 6 hours. Using an image analyzer (image processor for analytical pathology; IPAP), two variables were measured as indicators of in vivo gelatynolytic activity: optical density of gelatinolyzed area (ODG), and ratio of gelatinolyzed area (RGA). Also, we investigated the relationship between these indicators and the following variables: radiographic changes (Larsen grades), clinical data (C-reactive protein concentration), histological score of synovial tissue (modified Rooney's score), and expression of matrix metalloproteinase (MMP)-2, MMP-9, tissue inhibitor of metalloproteinase (TIMP)-1 and TIMP-2 (assessed by immunohistochemistry). RA synovium had significantly higher RGA and lower ODG than OA, indicating higher gelatinolytic activity in RA. Synovium from cases with Larsen grade IV or V had significantly lower ODG than cases with grade III, but there was no significant difference in RGA between grades. There was no significant correlation between gelatinolytic activity (ODG or RGA) and either CRP or modified Rooney's Histological Score. The results of ISZ indicate that the gelatinolyzed areas were mainly localized in the

  12. EDUCATION IN THE FIELD safety of human life AND THE SUSTAINABLE DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    M. A. Kartavykh

    2016-01-01

    Full Text Available The publication purpose - pedagogical design of education of bachelors in the field safety of human life in the context of ideas of a sustainable development as one of the modern and perspective directions of the higher education. Philosophical and methodological, scientific and technical and pedagogical aspects of provisions of the concept of a sustainable development are opened. It is shown that the greatest potential for realization of ideas of a sustainable development the invariant subject matter the " Safety of human life " studied by future bachelors irrespective of the direction and a profile of preparation possesses. The fundamental principles of education in the field safety of human life of future bachelors are formulated. Key functions of education of bachelors in the field of health and safety are defined: valuable and orientation, teoretiko-world outlook, it is constructive - activity, it is reflexive - estimated. The methodical tasks approaching the project to specific sociocultural and pedagogical conditions are opened: definition of target reference points, modular structuring content of education, development of procedural and technological features of creation of educational activity; diagnostics of results. The idea of a didactic cycle at development of the content of education in the field safety of human life is proved and opened. The educations of future bachelors got in the course of approbation results in the field safety of human life in the context of ideology of sustainable (safe development allow to speak about efficiency of the chosen scientific and methodological and organizational and technological bases and to project new models of practical experience in conditions of providing optimum ways of productive pedagogical interaction.

  13. Neuropsychological and psychological interventions for people with newly diagnosed epilepsy.

    Science.gov (United States)

    Jackson, Cerian F; Makin, Selina M; Baker, Gus A

    2015-07-22

    Many people with epilepsy report experiencing psychological difficulties such as anxiety, depression and neuropsychological deficits including memory problems. Research has shown that these difficulties are often present not only for people with chronic epilepsy but also for people with newly diagnosed epilepsy. Despite this, there are very few published interventions that detail means to help people with newly diagnosed epilepsy manage these problems. To identify and assess possible psychological and neuropsychological interventions for adults with newly diagnosed epilepsy. We searched the following databases on 30 June 2015: the Cochrane Epilepsy Group Specialized Register, the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE (Ovid), SCOPUS, PsycINFO, CINAHL, ClinicalTrials.gov and the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP). This review includes all randomised controlled trials, quasi-randomised controlled trials, prospective cohort controlled studies, and prospective before and after studies which include psychological or neuropsychological interventions for people with newly diagnosed epilepsy. We excluded studies that included people with epilepsy and any other psychological disorder or neurological condition. We excluded studies carried out which recruited only children. We used the standard methodological procedure expected by The Cochrane Collaboration. Two authors independently completed data extraction and risk of bias analysis. The results of this were cross-checked and third author resolved any discrepancies. In the event of missing data, we contacted the study authors. Meta-analysis was not completed due to differences in the intervention and outcomes reported in the two studies. We included two randomised controlled trials assessing psychological interventions for people with newly diagnosed epilepsy. One study assessed a cognitive behavioural intervention (CBI) in an adolescent

  14. Vibro-acoustic performance of newly designed tram track structures

    Science.gov (United States)

    Haladin, Ivo; Lakušić, Stjepan; Ahac, Maja

    2017-09-01

    Rail vehicles in interaction with a railway structure induce vibrations that are propagating to surrounding structures and cause noise disturbance in the surrounding areas. Since tram tracks in urban areas often share the running surface with road vehicles one of top priorities is to achieve low maintenance and long lasting structure. Research conducted in scope of this paper gives an overview of newly designed tram track structures designated for use on Zagreb tram network and their performance in terms of noise and vibration mitigation. Research has been conducted on a 150 m long test section consisted of three tram track types: standard tram track structure commonly used on tram lines in Zagreb, optimized tram structure for better noise and vibration mitigation and a slab track with double sleepers embedded in a concrete slab, which presents an entirely new approach of tram track construction in Zagreb. Track has been instrumented with acceleration sensors, strain gauges and revision shafts for inspection. Relative deformations give an insight into track structure dynamic load distribution through the exploitation period. Further the paper describes vibro-acoustic measurements conducted at the test site. To evaluate the track performance from the vibro-acoustical standpoint, detailed analysis of track decay rate has been analysed. Opposed to measurement technique using impact hammer for track decay rate measurements, newly developed measuring technique using vehicle pass by vibrations as a source of excitation has been proposed and analysed. Paper gives overview of the method, it’s benefits compared to standard method of track decay rate measurements and method evaluation based on noise measurements of the vehicle pass by.

  15. Microstructure and mechanical properties of newly developed aluminum–lithium alloy 2A97 welded by fiber laser

    Energy Technology Data Exchange (ETDEWEB)

    Fu, Banglong [Key Laboratory for Liquid–Solid Structural Evolution and Processing of Materials Ministry of Education, Shandong University, Jinan 250061 (China); Qin, Guoliang, E-mail: glqin@sdu.edu.cn [Key Laboratory for Liquid–Solid Structural Evolution and Processing of Materials Ministry of Education, Shandong University, Jinan 250061 (China); Meng, Xiangmeng; Ji, Yang; Zou, Yong [Key Laboratory for Liquid–Solid Structural Evolution and Processing of Materials Ministry of Education, Shandong University, Jinan 250061 (China); Lei, Zhen [Harbin Welding Institute, Harbin 150028 (China)

    2014-11-03

    The newly developed aluminum–lithium alloy 2A97 was for the first time joined by laser beam welding in order to meet the ever-increased long-term requirements of aerospace, aviation and armament industries. The weld appearance, microstructure, solute segregation, precipitate behavior, and their relationships with mechanical properties of welded joints were investigated. Sound joints with no crack and a few small porosities are obtained under appropriate heat inputs. As a result of heterogeneous nucleation involving the effect of Zr and Li, a non-dendritic equiaxed zone forms between partially melted zone and fusion zone. The crystal morphologies in fusion zone vary from columnar dendrite to equiaxed dendrite, with the increase of constitutional supercooling. Solute segregation leads to the variations of Cu content in grain interior and boundary, as well as the weak ability of re-precipitation of fusion zone. Most precipitates in the base metal dissolve during welding, and fusion zone contains a decreased quantity of δ′, β′, θ′, and T{sub 1}. The ultimate tensile strength of laser welded joints is 83.4% of that of the base metal, and can meet the application requirements from related industries, but the ductility still needs to be improved. Welding defects and loss of solid solution/precipitation hardened structure lead to the degradation of mechanical properties. Tensile fracture occurs in weld with the brittle intergranular dominated mode and premature failure occurs and extends in the equiaxed zone.

  16. Patients newly diagnosed with clinical type 2 diabetes during oral glucocorticoid treatment and observed for 14 years: all-cause mortality and clinical developments

    DEFF Research Database (Denmark)

    Olivarius, Niels de Fine; Siersma, Volkert Dirk; Dyring-Andersen, B.

    2011-01-01

    and sex and to 1.39 (0.92-2.11, p = 0.12, n = 1086) when risk factors, complications and cancer were added to the model. Apart from differences in age and overweight, patients in this relatively small sample of those diagnosed with clinical type 2 diabetes during GC treatment were comparable at diagnosis...... treatment. A population-based sample of 1369 people newly diagnosed with clinical type 2 diabetes underwent a clinical examination at diagnosis, and surviving patients were followed up 6 and 14 years later. Patients receiving oral GC treatment at diagnosis were compared with the other patients. Of 1369......Chronic exposure to glucocorticoids (GCs) has many side effects including glucose intolerance and diabetes and may accelerate the occurrence of cardiovascular disease and increase mortality. We studied the 14-year clinical development of diabetes in patients diagnosed with diabetes during GC...

  17. [Epidemiological characteristics of newly reported HIV infections in Chinese and Burmese residents, during 2012-2016 in Dehong Dai and Jingpo Autonomous Prefecture, Yunnan province].

    Science.gov (United States)

    Wang, J B; Chen, X C; Duan, X; Yang, J; Wang, Y K; Yang, T; Ye, R H; Yang, Y C; Yao, S T; Jiang, Y; Duan, S; He, N

    2017-10-10

    Objective: To understand the epidemiological characteristics of newly reported HIV infections in Chinese and Burmese residents during 2012-2016 in Dehong Dai and Jingpo Autonomous Prefecture of Yunnan province (Dehong) and to provide evidence for the development of related programs on prevention and control. Methods: All the HIV infections who were newly reported during 2012-2016 in Dehong, were recruited as the study subjects, with epidemiological characteristics of the cases analyzed by using the software SPSS 22.0. Results: A total of 5 692 HIV infections were newly reported between 2012 and 2016 (including 5 592 in this study), in which the Chinese patients accounted for 43.3 % (2 419) and the rest 56.7 % (3 173) were Burmese. Differences in age, gender and other social characteristics of these newly reported HIV infections were statistically significant between the Chinese and the Burmese (all p -values Chinese patients but through injecting drug use among the Burmese patients. Conclusions: Epidemiological characteristics of the newly reported HIV infections were different between the Chinese and the Burmese, between 2012 and 2016 in Dehong. Targeted prevention and control programs should be taken.

  18. Psychology as Field Experience: Impact on Attitudes Toward Social Interventions.

    Science.gov (United States)

    Snellman, Lynn A.; And Others

    An innovation in the teaching of undergraduate psychology courses is the implementation of a field experience that gives students the opportunity to apply newly learned skills and knowledge in a community setting. Changes in undergraduates' attitudes toward various delinquency interventions were examined as a result of participation in a…

  19. Development of Geomagnetic Monitoring System Using a Magnetometer for the Field

    Science.gov (United States)

    Lee, Young-Cheol; Kim, Sung-Wook; Choi, Eun-Kyeong; Kim, In-Soo

    2014-05-01

    Three institutes including KMA (Korea Meteorological Administration), KSWC (Korean Space Weather Center) of NRRA (National Radio Research Agency) and KIGAM (Korea Institute of Geoscience and Mineral Resources) are now operating magnetic observatories. Those observatories observe the total intensity and three components of geomagnetic element. This paper comes up with a magnetic monitoring system now under development that uses a magnetometer for field survey. In monitoring magnetic variations in areas (active faults or volcanic regions), more reliable results can be obtained when an array of several magnetometers are used rather than a single magnetometer. In order to establish and operate a magnetometer array, such factors as expenses, convenience of the establishment and operation of the array should be taken into account. This study has come up with a magnetic monitoring system complete with a magnetometer for the field survey of our own designing. A magnetic monitoring system, which is composed of two parts. The one is a field part and the other a data part. The field part is composed of a magnetometer, an external memory module, a power supply and a set of data transmission equipment. The data part is a data server which can store the data transmitted from the field part, analyze the data and provide service to the web. This study has developed an external memory module for ENVI-MAG (Scintrex Ltd.) using an embedded Cortex-M3 board, which can be programmed, attach other functional devices (SD memory cards, GPS antennas for time synchronization, ethernet cards and so forth). The board thus developed can store magnetic measurements up to 8 Gbytes, synchronize with the GPS time and transmit the magnetic measurements to the data server which is now under development. A monitoring system of our own developing was installed in Jeju island, taking measurements throughout Korea. Other parts including a data transfer module, a server and a power supply using solar

  20. Rigorous force field optimization principles based on statistical distance minimization

    Energy Technology Data Exchange (ETDEWEB)

    Vlcek, Lukas, E-mail: vlcekl1@ornl.gov [Chemical Sciences Division, Geochemistry & Interfacial Sciences Group, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-6110 (United States); Joint Institute for Computational Sciences, University of Tennessee, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-6173 (United States); Chialvo, Ariel A. [Chemical Sciences Division, Geochemistry & Interfacial Sciences Group, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-6110 (United States)

    2015-10-14

    We use the concept of statistical distance to define a measure of distinguishability between a pair of statistical mechanical systems, i.e., a model and its target, and show that its minimization leads to general convergence of the model’s static measurable properties to those of the target. We exploit this feature to define a rigorous basis for the development of accurate and robust effective molecular force fields that are inherently compatible with coarse-grained experimental data. The new model optimization principles and their efficient implementation are illustrated through selected examples, whose outcome demonstrates the higher robustness and predictive accuracy of the approach compared to other currently used methods, such as force matching and relative entropy minimization. We also discuss relations between the newly developed principles and established thermodynamic concepts, which include the Gibbs-Bogoliubov inequality and the thermodynamic length.

  1. Hope, emotion regulation, and psychosocial well-being in patients newly diagnosed with cancer.

    Science.gov (United States)

    Peh, Chao Xu; Kua, Ee Heok; Mahendran, Rathi

    2016-05-01

    Patients newly diagnosed with cancer are often confronted with feelings of uncertainty and life threat. A significant proportion may report impairments in psychosocial well-being. Previous studies examining protective psychological factors such as hope and emotion regulation (ER) have yet to investigate these processes concurrently within a common self-regulation framework and/or focus on newly diagnosed patients. The present study aimed to examine how hope and ER may relate to psychosocial outcomes of patients newly diagnosed with cancer. The present study used a cross-sectional design with self-report questionnaires. Participants were newly diagnosed patients (N = 101) recruited from three cancer therapy clinics in a hospital. Patients completed measures of hope, ER (cognitive reappraisal and expressive suppression), and psychosocial well-being (life satisfaction and negative affectivity). Findings showed that (1) hope and reappraisal, but not suppression, were associated with well-being and (2) the interaction between hope and reappraisal was associated with well-being; reappraisal was not associated with well-being in high hope patients, while high reappraisal was associated with better well-being in low hope patients. Individual differences in hope and reappraisal appeared to be associated with psychosocial outcomes in newly diagnosed cancer patients. Hopeful thinking appeared to benefit patients' psychosocial well-being. In addition, an interaction effect between hope and reappraisal suggested that reappraisal as an ER strategy may be particularly adaptive for patients with low hope.

  2. Development of high field superconducting Tokamak 'TRIAM-1M'

    International Nuclear Information System (INIS)

    Ito, Satoshi; Suzuki, Takao; Suzuki, Shohei; Nishi, Masatsugu; Kawasaki, Takahide.

    1984-01-01

    The tokamak nuclear fusion apparatus ''TRIAM-1M'' which is constructed in the Research Institute for Applied Mechanics, Kyushu University, has a number of distinctive features as compared with other tokamak projects, that is, the toroidal field coils are made of superconductors for the first time in Japan, and the apparatus is small and has strong magnetic field. Hitachi Ltd. designed and has forwarded the manufacture of the TRIAM-1M. In this paper, the total constitution of the apparatus and the design and manufacture of the plasma vacuum vessel, superconducting toroidal coils and others are reported. The objectives of research are the containment of strong field tokamak plasma and the establishment of the law of proportion, the development of turbulent flow heating method, the adoption of mixed wave current driving method and the practical use of Nb 3 Sn superconducting coils. The apparatus is composed of the vacuum vessel containing plasma, toroidal field coils, poloidal field coils, current transformer coils and turbulent flow heating coils for plasma heating, heat insulating vacuum vessel and supporting structures. The evacuating facility, helium liquefying refrigerator and cooling water facility are installed around the main body. (Kako, I.)

  3. Assessing the comparative effectiveness of newly marketed medications: methodological challenges and implications for drug development.

    Science.gov (United States)

    Schneeweiss, S; Gagne, J J; Glynn, R J; Ruhl, M; Rassen, J A

    2011-12-01

    Comparative-effectiveness research (CER) aims to produce actionable evidence regarding the effectiveness and safety of medical products and interventions as they are used outside of controlled research settings. Although CER evidence regarding medications is particularly needed shortly after market approval, key methodological challenges include (i) potential bias due to channeling of patients to the newly marketed medication because of various patient-, physician-, and system-related factors; (ii) rapid changes in the characteristics of the user population during the early phase of marketing; and (iii) lack of timely data and the often small number of users in the first few months of marketing. We propose a mix of approaches to generate comparative-effectiveness data in the early marketing period, including sequential cohort monitoring with secondary health-care data and propensity score (PS) balancing, as well as extended follow-up of phase III and phase IV trials, indirect comparisons of placebo-controlled trials, and modeling and simulation of virtual trials.

  4. Mentoring program for students newly enrolled in an Engineering Degree

    Directory of Open Access Journals (Sweden)

    Juan Pedro Peña-Martín

    2016-10-01

    Full Text Available This work presents a mentoring program for first year engineering students in the Telecommunications Engineering College (ETSIT at the University of Malaga (UMA. Actors involved in the program are professors from staff, veterans mentoring students and, of course, freshmen. All of them has been organized trough the Moodle based Virtual Learning Environment Platform of the UMA. The program has gone through several phases over three years. This paper shows the main objectives of this mentoring program, the initial design to get them where professors played mentor role, and successive changes made to try to improve the results, including the assumption of the mentor role by senior students (peer mentoring. The tools used for program evaluation are shown too. Despite the low participation, it has been a framework for the development of various educational and socializing activities (for mentors and mentees focused on developing generic competences. Furthermore, it has been a research tool to get a better understanding of problems affecting students newly enrolled.

  5. Measurement technique developments for LBE flows

    Energy Technology Data Exchange (ETDEWEB)

    Buchenau, D., E-mail: d.buchenau@fzd.de [Forschungszentrum Dresden-Rossendorf (FZD), 01314 Dresden (Germany); Eckert, S.; Gerbeth, G. [Forschungszentrum Dresden-Rossendorf (FZD), 01314 Dresden (Germany); Stieglitz, R. [Karlsruhe Institute of Technology (KIT), 76344 Eggenstein-Leopoldshafen (Germany); Dierckx, M. [SCK-CEN, Belgian Nuclear Research Centre, 2400 Mol (Belgium)

    2011-08-31

    We report on the development of measurement techniques for flows in lead-bismuth eutectic alloys (LBE). This paper covers the test results of newly developed contactless flow rate sensors as well as the development and test of the LIDAR technique for operational free surface level detection. The flow rate sensors are based on the flow-induced disturbance of an externally applied AC magnetic field which manifests itself by a modified amplitude or a modified phase of the AC field. Another concept of a force-free contactless flow meter uses a single cylindrical permanent magnet. The electromagnetic torque on the magnet caused by the liquid metal flow sets the magnet into rotation. The operation of those sensors has been demonstrated at liquid metal test loops for which comparative flow rate measurements are available, as well as at the LBE loops THESYS at KIT and WEBEXPIR at SCK-CEN. For the level detection a commercial LIDAR system was successfully tested at the WEBEXPIR facility in Mol and the THEADES loop in Karlsruhe.

  6. Newly qualified teachers' visions of science learning and teaching

    Science.gov (United States)

    Roberts, Deborah L.

    2011-12-01

    This study investigated newly qualified teachers' visions of science learning and teaching. The study also documented their preparation in an elementary science methods course. The research questions were: What educational and professional experiences influenced the instructor's visions of science learning and teaching? What visions of science learning and teaching were promoted in the participants' science methods course? What visions of science learning and teaching did these newly qualified teachers bring with them as they graduated from their teacher preparation program? How did these visions compare with those advocated by reform documents? Data sources included participants' assignments, weekly reflections, and multi-media portfolio finals. Semi-structured interviews provided the emic voice of participants, after graduation but before they had begun to teach. These data were interpreted via a combination of qualitative methodologies. Vignettes described class activities. Assertions supported by excerpts from participants' writings emerged from repeated review of their assignments. A case study of a typical participant characterized weekly reflections and final multi-media portfolio. Four strands of science proficiency articulated in a national reform document provided a framework for interpreting activities, assignments, and interview responses. Prior experiences that influenced design of the methods course included an inquiry-based undergraduate physics course, participation in a reform-based teacher preparation program, undergraduate and graduate inquiry-based science teaching methods courses, participation in a teacher research group, continued connection to the university as a beginning teacher, teaching in diverse Title 1 schools, service as the county and state elementary science specialist, participation in the Carnegie Academy for the Scholarship of Teaching and Learning, service on a National Research Council committee, and experience teaching a

  7. Field dodder – How to control it?

    Directory of Open Access Journals (Sweden)

    Marija Sarić-Krsmanović

    2015-04-01

    Full Text Available Broad geographic distribution and spectrum of hosts make field dodder, Cuscuta campestris, one of the most widespread and most harmful pests among flowering parasitic plants. Field dodder may become a problem in vegetable nurseries (e.g. tomato, sweet pepper and cabbage or in potato or some other crop grown in plastic greenhouses. However, the most devastating damage comes from field dodder outbreaks in newly-established perennial legume crops (alfalfa, clover, etc., which are generally the preferred hosts of this parasitic flowering species. Apart from alfalfa and clover, an expansion of field dodder has been observed in recent years in sugar beet, too. Different measures are available for controlling field dodder, from preventive (pure seeding material, tolerant cultivars, etc., to mechanical removal (mowing and hand weeding to herbicide treatments. The most successful control of field dodder requires a systematic approach ensured through integrated protection, which contributes to a more effective control of parasitic flowering plants.

  8. Biomechanical Skin Property Evaluation for Wounds Treated With Synthetic and Biosynthetic Wound Dressings and a Newly Developed Collagen Matrix During Healing of Superficial Skin Defects in a Rat Models.

    Science.gov (United States)

    Held, Manuel; Engelke, Anne-Sophie; Tolzmann, Dascha Sophie; Rahmanian-Schwarz, Afshin; Schaller, Hans-Eberhard; Rothenberger, Jens

    2016-09-01

    There is a high prevalence of superficial wounds such as partial-thickness burns. Treatment of these wounds frequently includes temporary application of wound dressings. The aim of this study was to compare a newly developed collagen matrix with commonly used temporary skin dressings for treatment of partial-thickness skin defects. Through a skin dermatome, 42 standardized superficial skin defects were generated on the back of 28 adult male Lewis rats. The wounds were treated with a synthetic wound dressing (Suprathel, Polymedics Innovations Inc, Woodstock, GA) (n = 14), a biosynthetic skin dressing (Biobrane, Smith & Nephew, Hull, UK) (n = 14), or a newly developed bovine collagen matrix, Collagen Cell Carrier (Viscofan BioEngineering, Weinheim, Germany) (n = 14). Biomechanical properties of the skin were determined and compared every 10 days over a 3-month period of using the Cutometer MPA 580 (Courage + Khazaka Electronic GmbH, Cologne, Germany). As opposed to healthy skin, statistically significant differences were detected between days 10 and 30, and between days 60 and 80, for calculated elasticity (Ue), firmness of skin (R0), and overall elasticity (R8). After 3 months, no statistically significant differences in skin elasticity were detected between the different wound dressings. The presented results give an opportunity to compare the wound dressings used for treatment with respect to skin elasticity and reveal the potential of the bovine collagen matrix in the treatment of superficial skin defects; therefore the results facilitate further evaluation of collagen matrix in surgical applications and regenerative medicine.

  9. GABA regulates synaptic integration of newly generated neurons in the adult brain

    Science.gov (United States)

    Ge, Shaoyu; Goh, Eyleen L. K.; Sailor, Kurt A.; Kitabatake, Yasuji; Ming, Guo-Li; Song, Hongjun

    2006-02-01

    Adult neurogenesis, the birth and integration of new neurons from adult neural stem cells, is a striking form of structural plasticity and highlights the regenerative capacity of the adult mammalian brain. Accumulating evidence suggests that neuronal activity regulates adult neurogenesis and that new neurons contribute to specific brain functions. The mechanism that regulates the integration of newly generated neurons into the pre-existing functional circuitry in the adult brain is unknown. Here we show that newborn granule cells in the dentate gyrus of the adult hippocampus are tonically activated by ambient GABA (γ-aminobutyric acid) before being sequentially innervated by GABA- and glutamate-mediated synaptic inputs. GABA, the major inhibitory neurotransmitter in the adult brain, initially exerts an excitatory action on newborn neurons owing to their high cytoplasmic chloride ion content. Conversion of GABA-induced depolarization (excitation) into hyperpolarization (inhibition) in newborn neurons leads to marked defects in their synapse formation and dendritic development in vivo. Our study identifies an essential role for GABA in the synaptic integration of newly generated neurons in the adult brain, and suggests an unexpected mechanism for activity-dependent regulation of adult neurogenesis, in which newborn neurons may sense neuronal network activity through tonic and phasic GABA activation.

  10. Top Information Need Priorities of Older Adults Newly Diagnosed With Active Myeloma.

    Science.gov (United States)

    Tariman, Joseph D; Doorenbos, Ardith; Schepp, Karen G; Singhal, Seema; Berry, Donna L

    2015-01-01

    Prioritizing patients' information needs maximizes efficiency. This study examined the information sources and priorities in a sample of older adults newly diagnosed with symptomatic myeloma requiring immediate therapy. An association analysis of whether information needs were influenced by sociodemographic variables such as age, gender, education, marital status, and income was also conducted. The Information Needs Questionnaire (INQ) and an investigator-developed interview schedule were administered to 20 older adults diagnosed with symptomatic myeloma during a 30- to 45-minute semistructured interview. We found that older adults newly diagnosed with symptomatic myeloma have different priorities of information needs when compared with younger patients diagnosed with various types of cancer. The top three priorities related to treatment, prognosis, and self-care. Sociodemographic variables did not influence the priorities of information needs among older adults with symptomatic myeloma. The Internet, physicians, family, and friends were among the top sources of information. Advanced practitioners in oncology should support and identify interventions that can enhance patients' learning process from these sources. Well poised to assist patients in searching credible and reliable Internet sources, advanced practitioners in oncology can provide patient education about different treatments and the impact of such treatments on prognosis (e.g., overall survival and likelihood of cure).

  11. Web-based stress management for newly diagnosed cancer patients (STREAM-1): a randomized, wait-list controlled intervention study.

    Science.gov (United States)

    Grossert, Astrid; Urech, Corinne; Alder, Judith; Gaab, Jens; Berger, Thomas; Hess, Viviane

    2016-11-03

    comparable to face-to-face interventions. With our study we open this field to the population of newly diagnosed cancer patients. We will not only assess clinical efficacy but also further refine the target population who has the most potential to benefit. An internet-based minimal-contact stress management program might be an attractive, time- and cost-effective way to effectively deliver psychological support to newly diagnosed cancer patients and an opportunity to include those who currently are not reached by conventional support. ClinicalTrials.gov NCT02289014 .

  12. Big earth-observation data analytics for modelling pan-tropical land-use change trajectories for newly deforested areas

    Science.gov (United States)

    Coca Castro, Alejandro; Reymondin, Louis; Rebetez, Julien; Fabio Satizabal Mejia, Hector; Perez-Uribe, Andres; Mulligan, Mark; Smith, Thomas; Hyman, Glenn

    2017-04-01

    Global land use monitoring is important to the the Sustainable Development Goals (SDGs). The latest advances in storage and manipulation of big earth-observation data have been key to developing multiple operational forest monitoring initiatives such as FORMA, Terra-i and Global Forest Change. Although the data provided by these systems are useful for identifying and estimating newly deforested areas (from 2000), they do not provide details about the land use to which these deforested areas are transitioned. This information is critical to understand the biodiversity and ecosystem services impact of deforestation and the resulting impacts on human wellbeing, locally and downstream. With the aim of contributing to current forest monitoring initiatives, this research presents a set of experimental case studies in Latin America which integrate existing land-change information derived from remote sensing image and aerial photography/ground datasets, high-temporal resolution MODIS data, advanced machine learning (i.e deep learning) and big data technologies (i.e. Hadoop and Spark) to assess land-use change trajectories in newly deforested areas in near real time.

  13. Resource selection for an interdisciplinary field: a methodology.

    Science.gov (United States)

    Jacoby, Beth E; Murray, Jane; Alterman, Ina; Welbourne, Penny

    2002-10-01

    The Health Sciences and Human Services Library of the University of Maryland developed and implemented a methodology to evaluate print and digital resources for social work. Although this methodology was devised for the interdisciplinary field of social work, the authors believe it may lend itself to resource selection in other interdisciplinary fields. The methodology was developed in response to the results of two separate surveys conducted in late 1999, which indicated improvement was needed in the library's graduate-level social work collections. Library liaisons evaluated the print collection by identifying forty-five locally relevant Library of Congress subject headings and then using these subjects or synonymous terms to compare the library's titles to collections of peer institutions, publisher catalogs, and Amazon.com. The collection also was compared to social work association bibliographies, ISI Journal Citation Reports, and major social work citation databases. An approval plan for social work books was set up to assist in identifying newly published titles. The library acquired new print and digital social work resources as a result of the evaluation, thus improving both print and digital collections for its social work constituents. Visibility of digital resources was increased by cataloging individual titles in aggregated electronic journal packages and listing each title on the library Web page.

  14. Protogalaxy interactions in newly formed clusters: Galaxy luminosities, colors, and intergalactic gas

    International Nuclear Information System (INIS)

    Silk, J.

    1978-01-01

    The role of protogalaxy interactions in galactic evolution is studied during the formation of galaxy clusters. In the early stages of the collapse, coalescent encounters of protogalaxies lead to the development of a galactic luminosity function. Once galaxies acquire appreciable random motions, mutual collisions between galaxies in rich clusters will trigger the collapse of interstellar clouds to form stars. This provides both a source for enriched intracluster gas and an interpretation of the correlation between luminosity and color for cluster elliptical galaxies. Other observational consequences that are considered include optical, X-ray, and diffuse nonthermal radio emission from newly formed clusters of galaxies

  15. Best management practices for newly weaned calves for improved health and well-being.

    Science.gov (United States)

    Wilson, B K; Richards, C J; Step, D L; Krehbiel, C R

    2017-05-01

    Morbidity and mortality in newly weaned calves resulting from bovine respiratory disease (BRD) continue to be the most significant problems facing the beef industry. Morbidity attributed to BRD accounts for approximately 75% of total feedlot morbidity. Several experiments have documented the economic impacts of BRD. Direct costs attributable to BRD include death loss, treatment and labor costs, and prevention costs, while indirect costs associated with BRD include decreased growth performance and feed efficiency, increased days on feed, and decreased carcass merit and market value. In recent years, cattle treated for BRD have returned $50 to $250 less per head at harvest than cattle never treated for BRD. Best management practices for newly weaned calves vary depending on a multitude of factors including: season of year calves are purchased, calf genetics, length of time in the marketing and transport channels, previous management and vaccination programs, and other factors. In general, calves purchased directly from a ranch have fewer health problems than calves purchased through auction markets. The longer a calf is in the marketing chain, the more likely health problems will be encountered. Calves that have spent several days in the marketing chain may develop clinical BRD before or very soon after arrival, whereas cattle with less time in the marketing chain may get sick later (2 to 4 wk), due to the length of time it takes for BRD to develop. On or before arrival, calves should be given a risk score (high, medium, or low) that relates to the quantity and magnitude of stress they have encountered and the probability they will develop BRD. High-risk calves typically will have been recently weaned, received no vaccinations, not been castrated or dehorned, been commingled, and moved through an auction market. Low-risk calves will often originate from a single source and will have gone through a preconditioning program that includes vaccination, castration

  16. DISABILITIES OF HANDS, FEET AND EYES IN NEWLY-DIAGNOSED LEPROSY PATIENTS IN EASTERN NEPAL

    NARCIS (Netherlands)

    SCHIPPER, A; LUBBERS, WJ; HOGEWEG, M; DESOLDENHOFF, R

    The objective of the study was to determine the magnitude of hand/feet/eye disabilities in newly diagnosed leprosy patients by examining all newly diagnosed leprosy patients who presented at the Eastern Leprosy Control Project (supported by The Netherlands Leprosy Relief Association), made up of a

  17. Antipsychotic medications and dental caries in newly diagnosed schizophrenia: A nationwide cohort study.

    Science.gov (United States)

    Hu, Kai-Fang; Chou, Yu-Hsiang; Wen, Yen-Hsia; Hsieh, Kun-Pin; Tsai, Jui-Hsiu; Yang, Pinchen; Yang, Yi-Hsin; Lin, Chun-Hung Richard

    2016-11-30

    We investigated the association between antipsychotic medications and the risk of dental caries in patients with schizophrenia. We enroled a nationwide cohort of patients with newly diagnosed schizophrenia within 1 year of dental caries development. Exposure to antipsychotics and other medications was categorised according to their type and duration, and the association between exposure and dental caries was assessed through logistic regressions. Of the 3610 patients with newly diagnosed schizophrenia, 2149 (59.5%) exhibited an incidence of treated dental caries. Logistic regression analysis identified a younger age, female sex, high income, a 2-year history of dental caries, and exposure to first-generation antipsychotics, and antihypertensives as independent risk factors for treated dental caries in patients with schizophrenia. Hyposalivation, the adverse effect of first-generation antipsychotics and antihypertensives, was associated with an increased risk of treated dental caries. However, hypersalivation from first-generation antipsychotics for dental caries was associated with a protective factor. These findings suggest that clinicians should pay attention to the aforementioned risk factors for dental caries in patients with schizophrenia, particularly while prescribing first-generation antipsychotics and antihypertensives to such patients. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  18. Delivering the diabetes education and self management for ongoing and newly diagnosed (DESMOND) programme for people with newly diagnosed type 2 diabetes

    DEFF Research Database (Denmark)

    Gillett, M.; Dallosso, H. M.; Dixon, S.

    2010-01-01

    intervention is £82 (-£831 to £1010) and the mean incremental cost per QALY gained is £2092. A probabilistic sensitivity analysis indicated that the likelihood that the DESMOND programme is cost effective at a threshold of £20 000 per QALY is 66% using trial based intervention costs and 70% using "real world......Objectives: To assess the long term clinical and cost effectiveness of the diabetes education and self management for ongoing and newly diagnosed (DESMOND) intervention compared with usual care in people with newly diagnosed type 2 diabetes. Design: We undertook a cost-utility analysis that used...... data from a 12 month, multicentre, cluster randomised controlled trial and, using the Sheffield type 2 diabetes model, modelled long term outcomes in terms of use of therapies, incidence of complications, mortality, and associated effect on costs and health related quality of life. A further cost...

  19. Load-Bearing Capacity and Retention of Newly Developed Micro-Locking Implant Prosthetic System: An In Vitro Pilot Study

    Directory of Open Access Journals (Sweden)

    Jae-Won Choi

    2018-04-01

    Full Text Available The aim of this study was to introduce the newly developed micro-locking implant prosthetic system and to evaluate the resulting its characteristics. To evaluate load-bearing capacity, 25 implants were divided into five groups: external-hexagon connection (EH, internal-octagon connection (IO, internal-hexagon connection (IH, one-body implant (OB, micro-locking implant system (ML. The maximum compressive load was measured using a universal testing machine (UTM according to the ISO 14801. Retention was evaluated in two experiments: (1 a tensile test of the structure modifications of the components (attachment and implant and (2 a tensile test after cyclic loading (total 5,000,000 cycles, 100 N, 2 Hz. The load-bearing capacity of the ML group was not significantly different from the other groups (p > 0.05. The number of balls in the attachment and the presence of a hexagonal receptacle did not show a significant correlation with retention (p > 0.05, but the shape of the retentive groove in the implant post had a statistically significant effect on retention (p < 0.05. On the other hand, the retention loss was observed during the initial 1,000,000 cycles, but an overall constant retention was maintained afterward. Various preclinical studies on this novel micro-locking implant prosthetic system should continue so that it can be applied in clinical practice.

  20. Direct writing of room temperature and zero field skyrmion lattices by a scanning local magnetic field

    KAUST Repository

    Zhang, Senfu; Zhang, Junwei; Zhang, Qiang; Barton, Craig; Neu, Volker; Zhao, Yuelei; Hou, Zhipeng; Wen, Yan; Gong, Chen; Kazakova, Olga; Wang, Wenhong; Peng, Yong; Garanin, Dmitry A.; Chudnovsky, Eugene M.; Zhang, Xixiang

    2018-01-01

    Magnetic skyrmions are topologically protected nanoscale spin textures exhibiting fascinating physical behaviors. Recent observations of room temperature skyrmions in sputtered multilayer films are an important step towards their use in ultra-low power devices. Such practical applications prefer skyrmions to be stable at zero magnetic fields and room temperature. Here, we report the creation of skyrmion lattices in Pt/Co/Ta multilayers by a scanning local field using magnetic force microscopy tips. We also show that those newly created skyrmion lattices are stable at both room temperature and zero fields. Lorentz transmission electron microscopy measurements reveal that the skyrmions in our films are of Néel-type. To gain a deeper understanding of the mechanism behind the creation of a skyrmion lattice by the scanning of local fields, we perform micromagnetic simulations and find the experimental results to be in agreement with our simulation data. This study opens another avenue for the creation of skyrmion lattices in thin films.

  1. Direct writing of room temperature and zero field skyrmion lattices by a scanning local magnetic field

    KAUST Repository

    Zhang, Senfu

    2018-03-29

    Magnetic skyrmions are topologically protected nanoscale spin textures exhibiting fascinating physical behaviors. Recent observations of room temperature skyrmions in sputtered multilayer films are an important step towards their use in ultra-low power devices. Such practical applications prefer skyrmions to be stable at zero magnetic fields and room temperature. Here, we report the creation of skyrmion lattices in Pt/Co/Ta multilayers by a scanning local field using magnetic force microscopy tips. We also show that those newly created skyrmion lattices are stable at both room temperature and zero fields. Lorentz transmission electron microscopy measurements reveal that the skyrmions in our films are of Néel-type. To gain a deeper understanding of the mechanism behind the creation of a skyrmion lattice by the scanning of local fields, we perform micromagnetic simulations and find the experimental results to be in agreement with our simulation data. This study opens another avenue for the creation of skyrmion lattices in thin films.

  2. Direct writing of room temperature and zero field skyrmion lattices by a scanning local magnetic field

    Science.gov (United States)

    Zhang, Senfu; Zhang, Junwei; Zhang, Qiang; Barton, Craig; Neu, Volker; Zhao, Yuelei; Hou, Zhipeng; Wen, Yan; Gong, Chen; Kazakova, Olga; Wang, Wenhong; Peng, Yong; Garanin, Dmitry A.; Chudnovsky, Eugene M.; Zhang, Xixiang

    2018-03-01

    Magnetic skyrmions are topologically protected nanoscale spin textures exhibiting fascinating physical behaviors. Recent observations of room temperature skyrmions in sputtered multilayer films are an important step towards their use in ultra-low power devices. Such practical applications prefer skyrmions to be stable at zero magnetic fields and room temperature. Here, we report the creation of skyrmion lattices in Pt/Co/Ta multilayers by a scanning local field using magnetic force microscopy tips. We also show that those newly created skyrmion lattices are stable at both room temperature and zero fields. Lorentz transmission electron microscopy measurements reveal that the skyrmions in our films are of Néel-type. To gain a deeper understanding of the mechanism behind the creation of a skyrmion lattice by the scanning of local fields, we perform micromagnetic simulations and find the experimental results to be in agreement with our simulation data. This study opens another avenue for the creation of skyrmion lattices in thin films.

  3. Singular trajectories: space-time domain topology of developing speckle fields

    Science.gov (United States)

    Vasil'ev, Vasiliy; Soskin, Marat S.

    2010-02-01

    It is shown the space-time dynamics of optical singularities is fully described by singularities trajectories in space-time domain, or evolution of transverse coordinates(x, y) in some fixed plane z0. The dynamics of generic developing speckle fields was realized experimentally by laser induced scattering in LiNbO3:Fe photorefractive crystal. The space-time trajectories of singularities can be divided topologically on two classes with essentially different scenario and duration. Some of them (direct topological reactions) consist from nucleation of singularities pair at some (x, y, z0, t) point, their movement and annihilation. They possess form of closed loops with relatively short time of existence. Another much more probable class of trajectories are chain topological reactions. Each of them consists from sequence of links, i.e. of singularities nucleation in various points (xi yi, ti) and following annihilation of both singularities in other space-time points with alien singularities of opposite topological indices. Their topology and properties are established. Chain topological reactions can stop on the borders of a developing speckle field or go to infinity. Examples of measured both types of topological reactions for optical vortices (polarization C points) in scalar (elliptically polarized) natural developing speckle fields are presented.

  4. Development and improvement of biological insecticides for pest control

    International Nuclear Information System (INIS)

    Vilas Boas, A.M.; Paccola-Meirelles, L.D.; Luna-ALves Lima, E.A.

    1992-01-01

    Strains of the fungus Beauveria bassiana (Bals) Vuill. were submitted to UV-light irradiation at doses inducing mutations. Three UV-light-resistant mutants were obtained from strain PL 256 and two from strain PL 196. The wild and mutant strains were tested for viability in 3 different manners: A) by incorporation a suspension into the soil of a field with newly emerged sugar cane; B) by applying the suspension only to the soil surface in a field with newly emerged sugar cane; C) by applying the suspension only to the surface in a field with 6-month old sugar cane. Soil samples were collected in different days after application, Conidia were counted and their viability was tested. Cytological studies were also carried out to determine the morphological traits of the strains. (M.A.C.)

  5. Thermal pulse measurements of space charge distributions under an applied electric field in thin films

    International Nuclear Information System (INIS)

    Zheng, Feihu; An, Zhenlian; Zhang, Yewen; Liu, Chuandong; Lin, Chen; Lei, Qingquan

    2013-01-01

    The thermal pulse method is a powerful method to measure space charge and polarization distributions in thin dielectric films, but a complicated calibration procedure is necessary to obtain the real distribution. In addition, charge dynamic behaviour under an applied electric field cannot be observed by the classical thermal pulse method. In this work, an improved thermal pulse measuring system with a supplemental circuit for applying high voltage is proposed to realize the mapping of charge distribution in thin dielectric films under an applied field. The influence of the modified measuring system on the amplitude and phase of the thermal pulse response current are evaluated. Based on the new measuring system, an easy calibration approach is presented with some practical examples. The newly developed system can observe space charge evolution under an applied field, which would be very helpful in understanding space charge behaviour in thin films. (paper)

  6. A high precision extrapolation method in multiphase-field model for simulating dendrite growth

    Science.gov (United States)

    Yang, Cong; Xu, Qingyan; Liu, Baicheng

    2018-05-01

    The phase-field method coupling with thermodynamic data has become a trend for predicting the microstructure formation in technical alloys. Nevertheless, the frequent access to thermodynamic database and calculation of local equilibrium conditions can be time intensive. The extrapolation methods, which are derived based on Taylor expansion, can provide approximation results with a high computational efficiency, and have been proven successful in applications. This paper presents a high precision second order extrapolation method for calculating the driving force in phase transformation. To obtain the phase compositions, different methods in solving the quasi-equilibrium condition are tested, and the M-slope approach is chosen for its best accuracy. The developed second order extrapolation method along with the M-slope approach and the first order extrapolation method are applied to simulate dendrite growth in a Ni-Al-Cr ternary alloy. The results of the extrapolation methods are compared with the exact solution with respect to the composition profile and dendrite tip position, which demonstrate the high precision and efficiency of the newly developed algorithm. To accelerate the phase-field and extrapolation computation, the graphic processing unit (GPU) based parallel computing scheme is developed. The application to large-scale simulation of multi-dendrite growth in an isothermal cross-section has demonstrated the ability of the developed GPU-accelerated second order extrapolation approach for multiphase-field model.

  7. Molecular modeling studies of structural properties of polyvinyl alcohol: a comparative study using INTERFACE force field.

    Science.gov (United States)

    Radosinski, Lukasz; Labus, Karolina

    2017-10-05

    Polyvinyl alcohol (PVA) is a material with a variety of applications in separation, biotechnology, and biomedicine. Using combined Monte Carlo and molecular dynamics techniques, we present an extensive comparative study of second- and third-generation force fields Universal, COMPASS, COMPASS II, PCFF, and the newly developed INTERFACE, as applied to this system. In particular, we show that an INTERFACE force field provides a possibility of composing a reliable atomistic model to reproduce density change of PVA matrix in a narrow temperature range (298-348 K) and calculate a thermal expansion coefficient with reasonable accuracy. Thus, the INTERFACE force field may be used to predict mechanical properties of the PVA system, being a scaffold for hydrogels, with much greater accuracy than latter approaches. Graphical abstract Molecular Dynamics and Monte Carlo studies indicate that it is possible to predict properties of the PVA in narrow temperature range by using the INTERFACE force field.

  8. Development of cyber training system for nuclear fields

    International Nuclear Information System (INIS)

    Kim, Young Taek; Park, Jong Kyun; Lee, Eui Jin; Lee, Han Young; Choi, Nan Young

    2002-02-01

    This report describes on technical contents related cyber training system construct on KAERI Nuclear Training Center, and on using cases of cyber education in domestic and foreign countries. Also realtime training system through the internet and cyber training management system for atomic fields is developed. All users including trainee, course managers and lecturers can use new technical for create new paradigm

  9. Human resources development in nuclear field in Japan

    International Nuclear Information System (INIS)

    Seki, Y.

    2007-01-01

    In this report, the recent topics in the nuclear field, some investigated data on human resources development (HRD) in nuclear field in Japan and the status of HRD and strategy are presented. We have investigated the basic data on HRD in nuclear field in some Asian countries so that the data could be used to develop HRD strategy. The basic data have been investigated for Japan in the following area. (1) Numbers of graduate and undergraduate students and faculty members for each of the nuclear related departments in the universities have been investigated; (2) The information on the academic associations and societies related to nuclear field has been collected; (3) In addition to the basic data directly related to human resources, the data related to the strategy for nuclear utilization such as the data on research reactors, the data on the level of the application of RI and radiation in medicine, agriculture, industry and environment and the future plan to construct NPPs, the number of NPPs being constructed and NPPs under operation have been collected and tabulated for each country. In Japan, many of the experienced nuclear engineers and scientists who have constructed nuclear power plants and developed the application methodology of RI and radiation, are aging and retiring. Also with the decrease in the construction of nuclear power plants and decrease in the nuclear energy research expenditures, it is becoming more difficult to maintain the present level of capability in designing and manufacturing of nuclear facilities. On the other hand, the educational infrastructures in the universities such as nuclear research reactors and the facilities where handling of radioactive materials is permitted, are deteriorating due to the difficulties to meet the more strict regulatory requirements. With the decrease in the popularity of nuclear energy and maturing of nuclear technology it is becoming more difficult to attract sufficient number of promising young individuals

  10. Highly radioresistant aramid fiber as a concrete-reinforcing material. Development of reinforced compound materials

    International Nuclear Information System (INIS)

    Udagawa, Akira; Moriya, Toshio.

    1997-01-01

    Nuclear installations, such as nuclear fusion reactor always receive strong influence from magnetic field. There, stray current is induced by the changes in magnetic fields among iron rods of the construction, resulting that the plasma control magnetic field might be disturbed. As the countermeasures for these troubles, iron rods mixed with non-magnetic Mn-steel have been used in JAERI, but it is insufficient to completely prevent such electromagnetic damages. Thus, aramid fiber reinforced plastics (ArFRP) was paid an attention as a concrete-reinforcing material. JAERI has been attempting to develop a radioresistant ArFRP jointly with Mitsui Construction Co., Ltd. and a highly efficient producing process of ArFRP was developed. The product had superior properties in respects of radioresistancy, heat-resistancy and durability. The properties of newly developed ArFRP rods were compared with those of the conventional ArFRP and iron rods. (M.N.)

  11. Pulsed critical current measurements of NbTi in perpendicular and parallel pulsed magnetic fields using the new Cryo-BI-Pulse System

    International Nuclear Information System (INIS)

    Stehr, V; Tan, K S; Hopkins, S C; Glowacki, B A; Keyser, A De; Bockstal, L Van; Deschagt, J

    2006-01-01

    Rapid transport current versus high magnetic field characterisation of high-irreversibility type II superconductors is important to maximise their critical parameters. HTS conductors are already used to produce insert coils that increase the fields of conventional magnets made from NbTi (Nb, Ta) 3 Sn and Nb 3 Al wires. There is fundamental interest in the study of HTS tapes and wires in magnetic fields higher than 21T, the current limit of superconducting magnets producing a DC field. Such fields can be obtained by using pulse techniques. High critical currents cannot be routinely measured with a continuous current applied at liquid helium, hydrogen or neon temperatures because of thermal and mechanical effects. A newly developed pulsed magnetic field and pulsed current system which allows rapid J c (B, T) measurements of the whole range of superconducting materials was tested with a multifilamentary NbTi wire in perpendicular and parallel orientations

  12. Cutting risk, boosting cash flow and developing marginal fields

    International Nuclear Information System (INIS)

    Baustad, T.; Courtin, G.; Davies, T.; Kenison, R.; Turnbull, J.; Gray, B.; Jalali, Y.; Remondet, J.C.; Hjelmsmark, L.; Oldfield, T.; Romano, C.; Saier, R.; Rannestad, G.

    1996-01-01

    To minimize financial risk and accelerate return on investment, oil companies are using low-cost, reusable production systems. The scope of these development options is illustrated by looking at three offshore case studies that range from extended well test to marginal field development. In each case, production systems technology has been deployed to provide superior data, early oil or both, thus reducing economic uncertainty and delivering accelerated cash flow. 10 figs., 23 refs

  13. Energization of electrons in a plasma beam entering a curved magnetic field

    International Nuclear Information System (INIS)

    Brenning, N.; Lindberg, L.; Eriksson, A.

    1980-09-01

    Earlier experiments have indicated that suprathermal electrons appear when a collisionless plasma flowing along a magnetic field enters a region where the magnetic field is curved. In the present investigation newly developed methods of He-spectroscopy based on the absolute intensities of the He I 3889 A and He II 4686 A lines are utilized to study the electron temperature and to estimate the population of non-thermal electrons. The density of helium added for the diagnostic purpose is so low that the flow is not disturbed. It is found that the intrusion of the plasma into a curved or transverse field gives rise to a slight increase (15-20%) in the electron temperature and a remarkable increase in the fraction of non-thermal (>100 eV) electrons from below 1% to as much as 20-25% of the total electron population. There are also indications that the energization of electrons is particularly efficient on that side of the plasma beam which becomes polarized to a positive potential when entering the curved field. The experiments are confined to the case of weak magnetic field, i.e. only the electrons are magnetically confined. New details of the electric field and potential structure are presented and discussed. Electric field components parallel to the magnetic field are likely to energize the electrons, probably through the run-away phenomenon. (Auth.)

  14. Confinement dynamics and boundary condition studies in the Reversed Field Pinch

    International Nuclear Information System (INIS)

    Schoenberg, K.F.; Ingraham, J.C.; Moses, R.W. Jr.

    1988-01-01

    The study of confinement dynamics, including investigation of the boundary conditions required for plasma sustainment, are central to the development of the Reversed Field Pinch (RFP) concept. Recently, several insights into confinement have emerged from a detailed investigation RFP electron and ion dynamics. These insights derive from the recognition that both magnetohydrodynamic (MHD) and electron kinetic effects play an important and coupled role in RFP stability, sustainment, and confinement. In this paper, we summarize the results of confinement studies on the ZT-40M experiment, and boundary condition studies on the Wisconsin non-circular RFP experiment. A brief description of the newly commissioned Madison Symmetric Torus (MST) is also presented. 28 refs., 3 figs

  15. Exploring selection and recruitment processes for newly qualified nurses: a sequential-explanatory mixed-method study.

    Science.gov (United States)

    Newton, Paul; Chandler, Val; Morris-Thomson, Trish; Sayer, Jane; Burke, Linda

    2015-01-01

    To map current selection and recruitment processes for newly qualified nurses and to explore the advantages and limitations of current selection and recruitment processes. The need to improve current selection and recruitment practices for newly qualified nurses is highlighted in health policy internationally. A cross-sectional, sequential-explanatory mixed-method design with 4 components: (1) Literature review of selection and recruitment of newly qualified nurses; and (2) Literature review of a public sector professions' selection and recruitment processes; (3) Survey mapping existing selection and recruitment processes for newly qualified nurses; and (4) Qualitative study about recruiters' selection and recruitment processes. Literature searches on the selection and recruitment of newly qualified candidates in teaching and nursing (2005-2013) were conducted. Cross-sectional, mixed-method data were collected from thirty-one (n = 31) individuals in health providers in London who had responsibility for the selection and recruitment of newly qualified nurses using a survey instrument. Of these providers who took part, six (n = 6) purposively selected to be interviewed qualitatively. Issues of supply and demand in the workforce, rather than selection and recruitment tools, predominated in the literature reviews. Examples of tools to measure values, attitudes and skills were found in the nursing literature. The mapping exercise found that providers used many selection and recruitment tools, some providers combined tools to streamline process and assure quality of candidates. Most providers had processes which addressed the issue of quality in the selection and recruitment of newly qualified nurses. The 'assessment centre model', which providers were adopting, allowed for multiple levels of assessment and streamlined recruitment. There is a need to validate the efficacy of the selection tools. © 2014 John Wiley & Sons Ltd.

  16. Newly-formed emotional memories guide selective attention processes: Evidence from event-related potentials

    OpenAIRE

    Harald T. Schupp; Ursula Kirmse; Ralf Schmälzle; Tobias Flaisch; Britta Renner

    2016-01-01

    Emotional cues can guide selective attention processes. However, emotional stimuli can both activate long-term memory representations reflecting general world knowledge and engage newly formed memory representations representing specific knowledge from the immediate past. Here, the self-completion feature of associative memory was utilized to assess the regulation of attention processes by newly-formed emotional memory. First, new memory representations were formed by presenting pictures depi...

  17. Study on time properties of newly type inorganic scintillator cerium fluoride (CeF3)

    International Nuclear Information System (INIS)

    Hu Mengchun; Zhou Dianzhong; Guo Cun; Ye Wenying

    2003-01-01

    CeF 3 is a newly fast time response inorganic scintillator, the time characteristics of which, developed in recent country in nearly year were studied in our works. The time characteristics are rise time, FWHM time and fall time for fast pulse radiation source. As the same time, authors have calculated and used the formula of pulse method gain to the decay time constant of crystal shining, the decay time constant measured is the same to the results of foreign references

  18. Identification of oligo-N-glycolylneuraminic acid residues in mammal-derived glycoproteins by a newly developed immunochemical reagent and biochemical methods.

    Science.gov (United States)

    Sato, C; Kitajima, K; Inoue, S; Inoue, Y

    1998-01-30

    The occurrence of the alpha2-->8-linked oligomeric form of N-glycolylneuraminic acid (oligo-Neu5Gc) residues in mammalian glycoproteins was unequivocally demonstrated using a newly developed anti-oligo/poly-Neu5Gc monoclonal antibody as well as by chemical and biochemical methods. First, the antibody, designated mAb.2-4B, which specifically recognized oligo/poly-Neu5Gc with a degree of polymerization of >2, was developed by establishing a hybridoma cell line from P3U1 myeloma cells fused with splenocytes from an MRL autoimmune mouse immunized with dipalmitoylphosphatidylethanolamine-conjugated oligo/poly-Neu5Gc. Second, oligo-Neu5Gc was shown to occur in glycoproteins derived from pig spleen by Western blot analysis using mAb.2-4B, which was also confirmed by fluorometric high performance liquid chromatographic analysis of the product of periodate oxidation/reduction/acid hydrolysis of the purified glycopeptide fractions and by TLC and 600-MHz 1H NMR spectroscopic analysis of their mild acid hydrolysates. Finally, the ubiquitous occurrence of oligo-Neu5Gc chains as glycoproteinaceous components in Wistar rat tissue was immunochemically indicated. This is the first example demonstrating the diversity in oligo/poly-Sia structure in mammalian glycoproteins, where only poly-N-acetylneuraminic acid is known to occur. Such diversity in oligo/poly-Sia structure also implicates a diverged array of biological functions of this glycan unit in glycoproteins.

  19. Association of copeptin and cortisol in newly diagnosed multiple sclerosis patients.

    Science.gov (United States)

    Baranowska-Bik, Agnieszka; Kochanowski, Jan; Uchman, Dorota; Litwiniuk, Anna; Kalisz, Malgorzata; Martynska, Lidia; Wolinska-Witort, Ewa; Baranowska, Boguslawa; Bik, Wojciech

    2015-05-15

    Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system. Obesity may increase the risk of developing MS. The aim of this study was to evaluate copeptin and cortisol plasma levels in newly diagnosed untreated MS patients and to determine whether copeptin and cortisol are related to the patients' clinical statuses. We report that copeptin and cortisol were higher in overweight/obese MS patients. Positive correlations were observed between the two parameters. We conclude that alterations of copeptin and cortisol levels in multiple sclerosis patients may be related to adiposity. An increase in cortisol may also be associated with copeptin secretion. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Identifying Malnutrition: Nutritional Status in Newly Diagnosed Patients With Cancer.

    Science.gov (United States)

    Krishnasamy, Karthikayini; Li Yoong, Tang; Mei Chan, Chong; Peng Choong, Lau; Chinna, Karuthan

    2017-02-01

    Malnutrition is common among patients with cancer, but little attention is given to its risks and consequences. The aim of this study is to assess the nutritional status and identify the factors associated with malnutrition among newly diagnosed patients with cancer. Patients admitted with newly diagnosed cancer at a teaching hospital in Malaysia were recruited from January to April 2015. Nutritional status was assessed before treatment initiation, and patients were classified into three categories. A total of 132 pretreatment patients were recruited into the study. About half were severely malnourished. Patients with stage III cancer had the highest prevalence of severe malnourishment. Clinical parameters and disease characteristics were significantly associated with nutritional status. Demographic variables were also statistically significantly associated with severe nutritional status.

  1. Interdisciplinary Professional Development Needs of Cooperative Extension Field Educators

    Science.gov (United States)

    Sondgerath, Travis

    2016-01-01

    The study discussed in this article sought to identify cross-program professional development needs of county-based Extension professionals (field educators). The study instrument was completed by 105 county-based Extension professionals. Interdisciplinary topics, such as program evaluation and volunteer management, were identified as subjects of…

  2. Development of a Micro-Fabricated Total-Field Magnetometer

    Science.gov (United States)

    2011-03-01

    are made with fluxgate technologies. Fluxgates have lower sensitivity than Cs magnetometers , yet they continue to be used in small wands simply...extraction process by providing the sensitivity of a Cs magnetometer with the convenience and low cost of a fluxgate wand. Extremely small and low cost...FINAL REPORT Development of a Micro-Fabricated Total-Field Magnetometer SERDP Project MR-1512 MARCH 2011 Mark Prouty Geometrics, Inc

  3. Assessment of metal retention in newly constructed highway embankments.

    Science.gov (United States)

    Werkenthin, Moritz; Kluge, Björn; Wessolek, Gerd

    2016-12-01

    Newly constructed embankments should provide both a specific bearing capacity to enable trafficability in emergency cases and a sufficient pollutant retention capacity to protect the groundwater. A number of lysimeters were installed along the A115 highway to determine total and dissolved metal concentrations in road runoff and in the soil solution of newly constructed embankments. Dissolved concentrations in soil solution of the embankments did not exceed the trigger values of the German legislation. Depending on the metal, total concentrations in soil solution were more than twice as high as dissolved concentrations. The high infiltration rates lead to increased groundwater recharge beneath the embankments (up to 4100 mm a -1 ). Although metal concentrations were not problematic from the legislators' point of view, the elevated infiltration rates beside the road facilitated the transfer of high metal loads into deeper soil layers and potentially into the groundwater as well.

  4. Noble Gas geochemistry of the newly discovered hydrothermal fields in the Gulf of California: preliminary He-isotope ratios from the Alarcon Rise and Pescadero basin vent sites

    Science.gov (United States)

    Spelz, R. M.; Lupton, J. E.; Evans, L. J.; Zierenberg, R. A.; Clague, D. A.; Neumann, F.; Paduan, J. B.

    2015-12-01

    Numerous submarine deep-sea hydrothermal vents related to volcanic activity of the East Pacific Rise (EPR) are situated along the Pacific margins of Mexico. Until recently, active hydrothermal venting was unknown between the Guaymas Basin and 21°N on the EPR. MBARI's recent oceanographic surveys have added 7 new active vent sites. In this study, we aimed to sample the high-temperature hydrothermal fluids emanating from two distinct vent sites, named Meyibo and Auka, located in the Alarcon Rise and Pescadero Basin, respectively. Mantle-derived He have long been identified in hydrothermal fluid releases. The presence of He in aqueous fluids with 3He/4He ratios greater than in-situ production values (~0.05 RA, where RA = air He or 1.4 x 10-6) indicates the presence of mantle-derived melts. Preliminary analyses of He-isotope ratios derived from the newly discovered Meyibo and Auka hydrothermal fields show high 3He/4He ratios (~8RA), typical of MORB's. Auka vent field, characterized by chimneys composed of light carbonate minerals and oil-like hydrocarbons, and temperatures between 250-290oC, show average values of ~7.87RA. In contrast, the black-smokers at the Meyibo field, composed of dark sulfide minerals and temperatures over 350oC, yielded a higher He ratio of ~8.24RA. Recently, it has become clear that regional maximum mantle He values correlate with the velocity structure in the mantle, therefore, He has the potential to map regions of the underlying mantle that are undergoing partial melting. Seismic records could then be compared with the geochemical He ratio signal and supply information regarding tectonics and other processes involved in the generation of these gases. The data presented here will be completing a totally new inventory of He results from hydrothermal vents in the EPR and fault-termination basins distributed along the P-NA plate boundary in the Gulf of California. The results will be further coupled with the analysis of other geochemical

  5. Design and Development of a Magneto-Optic Sensor for Magnetic Field Measurements

    Directory of Open Access Journals (Sweden)

    Sarbani CHAKRABORTY

    2015-01-01

    Full Text Available A magneto-optic sensor is developed using a Terbium Doped Glass (TDG element as a Faraday rotation sensor and optical fiber as light transmitting and receiving medium. Online LabView based application software is developed to process the sensor output. The system is used to sense the magnetic field of a DC motor field winding in industrial environment. The sensor output is compared with the magnetic flux density variation obtained with a calibrated Hall Magnetic sensor (Gauss Meter. A linear variation of sensor output over wide range of current passing through the field winding is obtained. Further the results show an improved sensitivity of magneto-optic sensor over the Hall sensor.

  6. Atom-probe field-ion-microscopy study of Fe-Ti alloys

    International Nuclear Information System (INIS)

    Pickering, H.W.; Kuk, Y.; Sakurai, T.

    1980-01-01

    A newly developed high-performance atom-probe (field ion microscope) was employed for the composition analysis of Fe-Ti alloys and their interactions with ambient gas, such as H 2 and O 2 . With a mass resolution (m/Δm) better than 2000 and a spatial resolution of a few A, all isotopes of Fe and Ti and their hydrides and other compounds are clearly resolved during the depth profile study. Some of our findings are: (1) Titanium segregated on the surface and grain boundaries upon heating (greater than or equal to 900 0 C), in the form of oxides, and (2) some Ti in the bulk forms clusters of various sizes with C, O, and/or N as nuclei

  7. Experimental Studies on the Behavior of a Newly-Developed Type of Self-Insulating Concrete Masonry Shear Wall under in-Plane Cyclic Loading

    Directory of Open Access Journals (Sweden)

    Abu-Bakre Abdelmoneim Elamin Mohamad

    2017-04-01

    Full Text Available This study aimed to investigate the inelastic behavior of a newly-developed type of self-insulating concrete masonry shear wall (SCMSW under in-plane cyclic loading. The new masonry system was made from concrete blocks with special configurations to provide a stronger bond between units than ordinary concrete masonry units. A total of six fully-grouted SCMSWs were prepared with different heights (1.59 to 5.78 m and different vertical steel configurations. The developed masonry walls were tested under in-plane cyclic loading and different constant axial load ratios. In addition, the relationship between the amount of axial loading, the amount of the flexural reinforcement and the wall aspect ratios and the nonlinear hysteretic response of the SCMSW was evaluated. The results showed that the lateral load capacity of SCMSW increases with the amount of applied axial load and the amount of vertical reinforcement. However, the lateral load capacity decreases as the wall aspect ratio increases. The existence of the boundary elements at the SCMSW ends increases the ductility and the lateral load capacity. Generally, the SCMSW exhibited predominantly flexural behavior. These results agreed with those reported in previous research for walls constructed with ordinary units.

  8. Recent developments in chiral gauge theories: approach of infinitely many fermi fields

    International Nuclear Information System (INIS)

    Narayanan, R.

    1994-01-01

    I present the recent developments in a specific sub-field of chiral gauge theories on the lattice. This subfield pertains to the use of infinitely many fermi fields to describe a single chiral field. In this approach, both anomalous and anomaly free theories can be discussed in equal footing. It produces the correct anomaly in the continuum limit. It has the potential to describe fermion number violating processes in the presence of a gauge field background with non-trivial topological charge on a finite lattice. (orig.)

  9. Workplace Violence and Job Outcomes of Newly Licensed Nurses.

    Science.gov (United States)

    Chang, Hyoung Eun; Cho, Sung-Hyun

    2016-12-01

    The purpose of this study was to examine the prevalence of workplace violence toward newly licensed nurses and the relationship between workplace violence and job outcomes. An online survey was conducted of newly licensed registered nurses who had obtained their license in 2012 or 2013 in South Korea and had been working for 5-12 months after first being employed. The sample consisted of 312 nurses working in hospitals or clinics. The Copenhagen Psychosocial Questionnaire II was used to measure violence and nurse job outcomes. Multiple linear and logistic regression analyses were conducted to examine the relationship between violence and job outcomes. Verbal abuse was most prevalent (59.6%), followed by threats of violence (36.9%), physical violence (27.6%), bullying (25.6%), and sexual harassment (22.4%). Approximately three quarters of the nurses had experienced at least one type of violence. The main perpetrators were patients and nurse colleagues, although the distribution of perpetrators varied depending on the type of violence. Bullying had a significant relationship with all four job outcomes (job satisfaction, burnout, commitment to the workplace, and intent to leave), while verbal abuse was associated with all job outcomes except for intent to leave. Violence perpetrated by nurse colleagues had a significant relationship with all four job outcomes, while violence by physicians had a significant inverse relationship with job satisfaction. Workplace violence is experienced by a high percentage of newly licensed nurses, and is associated with their job outcomes. Copyright © 2016. Published by Elsevier B.V.

  10. Evaluation Method for Fieldlike-Torque Efficiency by Modulation of the Resonance Field

    Science.gov (United States)

    Kim, Changsoo; Kim, Dongseuk; Chun, Byong Sun; Moon, Kyoung-Woong; Hwang, Chanyong

    2018-05-01

    The spin Hall effect has attracted a lot of interest in spintronics because it offers the possibility of a faster switching route with an electric current than with a spin-transfer-torque device. Recently, fieldlike spin-orbit torque has been shown to play an important role in the magnetization switching mechanism. However, there is no simple method for observing the fieldlike spin-orbit torque efficiency. We suggest a method for measuring fieldlike spin-orbit torque using a linear change in the resonance field in spectra of direct-current (dc)-tuned spin-torque ferromagnetic resonance. The fieldlike spin-orbit torque efficiency can be obtained in both a macrospin simulation and in experiments by simply subtracting the Oersted field from the shifted amount of resonance field. This method analyzes the effect of fieldlike torque using dc in a normal metal; therefore, only the dc resistivity and the dimensions of each layer are considered in estimating the fieldlike spin-torque efficiency. The evaluation of fieldlike-torque efficiency of a newly emerging material by modulation of the resonance field provides a shortcut in the development of an alternative magnetization switching device.

  11. Development of Cloud Chamber by Using Peltier Device

    International Nuclear Information System (INIS)

    Woo, Jong Kwan; Kwon, Jin Young; Park, Sang Tae

    2011-01-01

    In this research, we developed the newly cloud chamber apparatus by using Peltier device to apply nuclear physics experiment in high school or university. We observed the cosmic rays track by using the developed apparatus and a camcorder. And we compared and analyzed the acquired data. From the results, we acquired the following conclusions and suggestions : First, it is very difficult to observe the cosmic rays track in the typical cloud chamber because of the low frequency of it. But in the newly developed cloud chamber we can observe easily the cosmic rays track owing to the high frequency of it. Second, when we do the experiment with the newly developed apparatus, we found that the cosmic rays track happens well under the condition that the temperature of the upper place of cooling plate must be below 5 degree Celsius with more than isopropanol 1.04X10 -5 ml.mm -3 . Third, the newly developed apparatus will be improved to have better precision by controlling the temperature of cooling plate in the cloud chamber by current intensity. Therefore we think that it is very useful to use the newly developed apparatus in the nuclear physics experiment in high school or university.

  12. Development of Cloud Chamber by Using Peltier Device

    Energy Technology Data Exchange (ETDEWEB)

    Woo, Jong Kwan [Jae Hyun High School, Seoul (Korea, Republic of); Kwon, Jin Young [Jeon Min High School, Daejeon (Korea, Republic of); Park, Sang Tae [Dept. of Physics Education, Kongju National University, Kongju (Korea, Republic of)

    2011-09-15

    In this research, we developed the newly cloud chamber apparatus by using Peltier device to apply nuclear physics experiment in high school or university. We observed the cosmic rays track by using the developed apparatus and a camcorder. And we compared and analyzed the acquired data. From the results, we acquired the following conclusions and suggestions : First, it is very difficult to observe the cosmic rays track in the typical cloud chamber because of the low frequency of it. But in the newly developed cloud chamber we can observe easily the cosmic rays track owing to the high frequency of it. Second, when we do the experiment with the newly developed apparatus, we found that the cosmic rays track happens well under the condition that the temperature of the upper place of cooling plate must be below 5 degree Celsius with more than isopropanol 1.04X10{sup -5}ml.mm{sup -3}. Third, the newly developed apparatus will be improved to have better precision by controlling the temperature of cooling plate in the cloud chamber by current intensity. Therefore we think that it is very useful to use the newly developed apparatus in the nuclear physics experiment in high school or university.

  13. Chenodeoxycholic acid reduces intestinal permeability in newly weaned piglets

    NARCIS (Netherlands)

    Meer, van der Y.; Gerrits, W.J.J.; Bosch, van den M.; Holst, J.J.; Moreto, M.; Buurman, W.A.; Kulik, W.; Kempen, van T.A.T.G.

    2012-01-01

    Piglets are highly susceptible to gut health-related problems. Intravenously administered chenodeoxycholic acid (CDCA) affects gut health mediated through glucagon-like peptide 2 (GLP-2). To test whether CDCA is a suitable feed additive for improving gut health, a trial was performed with newly

  14. ALS Biomarkers for Therapy Development: State of the Field & Future Directions

    Science.gov (United States)

    Benatar, Michael; Boylan, Kevin; Jeromin, Andreas; Rutkove, Seward B.; Berry, James; Atassi, Nazem; Bruijn, Lucie

    2015-01-01

    Biomarkers have become the focus of intense research in the field of amyotrophic lateral sclerosis (ALS), with the hope that they might aid therapy development efforts. Notwithstanding the discovery of many candidate biomarkers, none have yet emerged as validated tools for drug development. In this review we present a nuanced view of biomarkers based on the perspective of the FDA; highlight the distinction between discovery and validation; describe existing and emerging resources; review leading biological fluid-based, electrophysiological and neuroimaging candidates relevant to therapy development efforts; discuss lessons learned from biomarker initiatives in related neurodegenerative diseases; and outline specific steps that we, as a field, might take in order to hasten the development and validation of biomarkers that will prove useful in enhancing efforts to develop effective treatments for ALS patients. Most important among these perhaps is the proposal to establish a federated ALS Biomarker Consortium (ABC) in which all interested and willing stakeholders may participate with equal opportunity to contribute to the broader mission of biomarker development and validation. PMID:26574709

  15. PDF approach for turbulent scalar field: Some recent developments

    Science.gov (United States)

    Gao, Feng

    1993-01-01

    The probability density function (PDF) method has been proven a very useful approach in turbulence research. It has been particularly effective in simulating turbulent reacting flows and in studying some detailed statistical properties generated by a turbulent field There are, however, some important questions that have yet to be answered in PDF studies. Our efforts in the past year have been focused on two areas. First, a simple mixing model suitable for Monte Carlo simulations has been developed based on the mapping closure. Secondly, the mechanism of turbulent transport has been analyzed in order to understand the recently observed abnormal PDF's of turbulent temperature fields generated by linear heat sources.

  16. Timing of revenue streams from newly recruited faculty: implications for faculty retention.

    Science.gov (United States)

    Joiner, Keith A; Hiteman, Sarah; Wormsley, Steven; St Germain, Patricia

    2007-12-01

    To determine the timing and magnitude of revenues generated by newly recruited faculty, to facilitate configuration of recruitment packages appropriately matched to expected financial returns. The aggregate of all positive cash flows to central college of medicine administration -- from research, clinical care, tuition, philanthropy, and royalties and patents, from all faculty newly recruited to the University of Arizona College of Medicine between 1998 and 2004 -- was quantified using the net present value (npv) methodology, which incorporates the time value of money. Tenure-track faculty and, in particular, those with laboratory research programs, generated the highest positive central cash flows. The npv for positive cash flows (npv[+]) during 6 and 10 years for newly recruited assistant professors with laboratory research programs were $118,600 and $255,400, respectively, and, for professors with laboratory research programs, $172,600 and $298,000, respectively (associate professors were not analyzed because of limited numbers). Faculty whose appointments at the University of Arizona College of Medicine exceeded 15 years in duration were the most productive in central revenue generation, far in excess of their numbers proportionate to the total. The results emphasize the critical importance of faculty retention, because even those newly recruited faculty who are most successful in central revenue generation (tenure track with laboratory research programs) must be retained for periods well in excess of 10 years to recoup the initial central investment required for their recruitment.

  17. Variable stars in the field of open cluster NGC 2126

    International Nuclear Information System (INIS)

    Liu Shunfang; Wu Zhenyu; Zhang Xiaobin; Wu Jianghua; Ma Jun; Jiang Zhaoji; Chen Jiansheng; Zhou Xu

    2009-01-01

    We report the results of a time-series CCD photometric survey of variable stars in the field of open cluster NGC 2126. In about a one square degree field covering the cluster, a total of 21 variable candidates are detected during this survey, of which 16 are newly found. The periods, classifications and spectral types of 14 newly discovered variables are discussed, which consist of six eclipsing binary systems, three pulsating variable stars, three long period variables, one RS CVn star, and one W UMa or δ Scuti star. In addition, there are two variable candidates, the properties of which cannot be determined. By a method based on fitting observed spectral energy distributions of stars with theoretical ones, the membership probabilities and the fundamental parameters of this cluster are determined. As a result, five variables are probably members of NGC 2126. The fundamental parameters of this cluster are determined as: metallicity to be 0.008 Z o-dot , age log(t) = 8.95, distance modulus (m - M) 0 = 10.34 and reddening value E (B - V) = 0.55 mag.

  18. Idaho Nuclear Technology and Engineering Center Newly Generated Liquid Waste Demonstration Project Feasibility Study

    International Nuclear Information System (INIS)

    Herbst, A.K.

    2000-01-01

    A research, development, and demonstration project for the grouting of newly generated liquid waste (NGLW) at the Idaho Nuclear Technology and Engineering Center is considered feasible. NGLW is expected from process equipment waste, decontamination waste, analytical laboratory waste, fuel storage basin waste water, and high-level liquid waste evaporator condensate. The potential grouted waste would be classed as mixed low-level waste, stabilized and immobilized to meet RCRA LDR disposal in a grouting process in the CPP-604 facility, and then transported to the state

  19. Pulsed Electric Fields for Biological Weapons Defense

    National Research Council Canada - National Science Library

    Gundersen, Martin A

    2008-01-01

    Pulsed power for biological investigations newly developed at USC include a fast diode-based systems designed to drive cell suspensions in a microscope slide electrode microchamber for observations...

  20. Development of a backscattering type ultraviolet apertureless near-field scanning optical microscope.

    Science.gov (United States)

    Kwon, Sangjin; Jeong, Hyun; Jeong, Mun Seok; Jeong, Sungho

    2011-08-01

    A backscattering type ultraviolet apertureless near-field scanning optical microscope (ANSOM) for the correlated measurement of topographical and optical characteristics of photonic materials with high optical resolution was developed. The near-field Rayleigh scattering image of GaN covered with periodic submicron Cr dots showed that optical resolution around 40 nm was achievable. By measuring the tip scattered photoluminescence of InGaN/GaN multi quantum wells, the applicability of the developed microscope for high resolution fluorescence measurement was also demonstrated.

  1. 'BRICS without straw'? A systematic literature review of newly emerging economies' influence in global health.

    Science.gov (United States)

    Harmer, Andrew; Xiao, Yina; Missoni, Eduardo; Tediosi, Fabrizio

    2013-04-15

    Since 2010, five newly emerging economies collectively known as 'BRICS' (Brazil, India, Russia, China and South Africa) have caught the imagination, and scholarly attention, of political scientists, economists and development specialists. The prospect of a unified geopolitical bloc, consciously seeking to re-frame international (and global) health development with a new set of ideas and values, has also, if belatedly, begun to attract the attention of the global health community. But what influence, if any, do the BRICS wield in global health, and, if they do wield influence, how has that influence been conceptualized and recorded in the literature? We conducted a systematic literature review in (March-December 2012) of documents retrieved from the databases EMBASE, PubMed/Medline, Global Health, and Google Scholar, and the websites of relevant international organisations, research institutions and philanthropic organisations. The results were synthesised using a framework of influence developed for the review from the political science literature. Our initial search of databases and websites yielded 887 documents. Exclusion criteria narrowed the number of documents to 71 journal articles and 23 reports. Two researchers using an agreed set of inclusion criteria independently screened the 94 documents, leaving just 7 documents. We found just one document that provided sustained analysis of the BRICS' collective influence; the overwhelming tendency was to describe individual BRICS countries influence. Although influence was predominantly framed by BRICS countries' material capability, there were examples of institutional and ideational influence - particularly from Brazil. Individual BRICS countries were primarily 'opportunity seekers' and region mobilisers but with potential to become 'issue leaders' and region organisers. Though small in number, the written output on BRICS influence in global health has increased significantly since a similar review conducted in

  2. Scandinavian exceptionalism? Civic integration and labour market activation for newly arrived immigrants

    DEFF Research Database (Denmark)

    Breidahl, Karen Nielsen

    2017-01-01

    models have been resilient: Based on an in-depth historical and comparative analysis of labour market activation policies targeting newly arrived immigrants in Sweden, Norway, and Denmark since the early 1990s, the article contributes to the overall question: To what extent do the institutional pathways...... of the Scandinavian welfare states prevail when confronted with newcomers? Activation policies targeting newly arrived immigrants exemplifies how the ambition of states to promote functional, individual autonomy is also an important, ongoing process in diverse policy areas of the welfare state and not restricted...

  3. Distinguishing Newly Born Strange Stars from Neutron Stars with g-Mode Oscillations

    International Nuclear Information System (INIS)

    Fu Weijie; Wei Haiqing; Liu Yuxin

    2008-01-01

    The gravity-mode (g-mode) eigenfrequencies of newly born strange quark stars (SQSs) and neutron stars (NSs) are studied. It is found that the eigenfrequencies in SQSs are much lower than those in NSs by almost 1 order of magnitude, since the components of a SQS are all extremely relativistic particles while nucleons in a NS are nonrelativistic. We therefore propose that newly born SQSs can be distinguished from the NSs by detecting the eigenfrequencies of the g-mode pulsations of supernovae cores through gravitational radiation by LIGO-class detectors

  4. Ten Key Steps to Developing a Programme of University Mentoring for Newly Enrolled Students

    Directory of Open Access Journals (Sweden)

    Raquel Casado-Muñoz

    2015-05-01

    Full Text Available Peer mentoring or tutoring is an educational guidance method that is growing in universities around the world. Directed at the integration of students over the first year of university studies, it is based on the support and guidance that a more experienced student offers to a recently enrolled fellow student. It is a recent process in Spain which started a little over a decade ago, but each course brings more experiences. This article, derived from research, seeks to identify a series of key steps and ideas to implement this type of programme. The summary of the proposals stems from three main sources: a the experience and assessment of the Mentoring Programme at the University of Burgos; b the review of the peer mentoring programs implemented at 35 Spanish universities; and c the review, comparison and adaptation of formal mentoring to the university according to Perrone (2003.  The outcomes may be especially useful for those universities that wish to start mentoring programmes, and as a source of reflection and comparison for those with greater experience. We believe that special attention should be given on increasing and improving participation in the mentoring of newly enrolled students and on monitoring and assessing the whole process.

  5. The contribution of farmer field schools to rural development in Nepal

    NARCIS (Netherlands)

    Westendorp, A.M.B.

    2012-01-01

     This thesis argues that Farmer Field Schools in Nepal contributed to agriculture and rural development and to gendered empowerment. The Nepalese government, but also NGOs involved in FFS applied a rather technocratic approach towards development (Li, 1999) and assumed that will well-defined

  6. Managing human resources in the field of nuclear energy

    International Nuclear Information System (INIS)

    2009-01-01

    The nuclear field, comprising industry, government authorities, regulators, R and D organizations and educational institutions, relies heavily on a specialized, highly trained and motivated workforce for its sustainability. An ageing workforce, declining student enrolment and the resultant risk of losing accumulated nuclear knowledge and experience for expanding or newly established nuclear programmes are all serious challenges that influence the management of human resources (HR) in the nuclear field. The management of human resources requires particular attention in the field of nuclear energy, both because of the high standards of performance expected in this field and the considerable time needed to develop such specialists. The peaceful uses of nuclear energy were primarily developed during the second half of the twentieth century. The nuclear field is now at a mature stage of development, with those who were pioneers in the field having retired and their responsibilities handed over to subsequent generations. For those aspects of the nuclear field related to nuclear power, a great deal of effort has been devoted to managing and continuing to improve the safety and operational performance of existing facilities. However, indications are that the next decades may see considerable expansion to meet increasing energy needs, while responding to concerns about the environment, including global warming. Thus, in the nuclear field, those Member States with existing nuclear power programmes may be forced to replace a large part of their current workforce, while also attracting, recruiting and preparing a fresh workforce for the new facilities being planned. At the same time, those who will be initiating nuclear power programmes, or other peaceful applications, will be developing HR for their programmes. In the past, the development of human resources in the nuclear field has depended on considerable support from organizations in the country of origin of the technology

  7. The use of environmental assessments in the Brae field development

    International Nuclear Information System (INIS)

    Grogan, W.C.

    1991-01-01

    This paper reviews the principle environmental aspects associated with North Sea offshore oil and gas development and through the case history of Marathon Oil UK's Brae Field Development illustrates the scope and function of environmental assessments as applied to offshore developments. Details of the approach taken are described including the chronological evolution of the scope and aims of individual assessments. Examples of discharge inventory preparation, effluent and receiving environment monitoring programs, audits and inspections and procedures are described. The role of these components in the development of environmental management systems is discussed

  8. Effects of supervision on tax compliance: Evidence from a field experiment in Austria

    Science.gov (United States)

    Gangl, Katharina; Torgler, Benno; Kirchler, Erich; Hofmann, Eva

    2014-01-01

    We conduct a field experiment on tax compliance, focusing on newly founded firms. As a novelty the effect of tax authorities’ supervision on timely tax payments is examined. Interestingly, results show no positive overall effect of close supervision on tax compliance. PMID:25843992

  9. Optimization of a large integrated area development of gas fields offshore Sarawak, Malaysia

    International Nuclear Information System (INIS)

    Inyang, S.E.; Tak, A.N.H.; Costello, G.

    1995-01-01

    Optimizations of field development plans are routine in the industry. The size, schedule and nature of the upstream gas supply project to the second Malaysia LNG (MLNG Dua) plant in Bintulu, Sarawak made the need for extensive optimizations critical to realizing a robust and cost effective development scheme, and makes the work of more general interest. The project comprises the upstream development of 11 offshore fields for gas supply to MLNG Dua plant at an initial plateau production of 7.8 million tons per year of LNG. The gas fields span a large geographical area in medium water depths (up to 440 ft), and contain gas reserves of a distinctly variable gas quality. This paper describes the project optimization efforts aimed to ensure an upstream gas supply system effectiveness of over 99% throughout the project life while maintaining high safety and environmental standards and also achieving an economic development in an era of low hydrocarbon prices. Fifty percent of the first of the three phases of this gas supply project has already been completed and the first gas from these fields is scheduled to be available by the end of 1995

  10. A multidisciplinary prostate cancer clinic for newly diagnosed patients: developing the role of the advanced practice nurse.

    Science.gov (United States)

    Madsen, Lydia T; Craig, Catherine; Kuban, Deborah

    2009-06-01

    Newly diagnosed patients with prostate cancer have various treatment options, and a multidisciplinary prostate cancer clinic (MPCC) can present all options in a single setting. An MPCC was started in 2004 at the University of Texas M.D. Anderson Cancer Center, and 258 patients with prostate cancer were evaluated in its first year. The clinic expanded in 2006 and an oncology advanced practice nurse (APN) was recruited to address specific objectives. The APN role was used to implement a quality-of-life protocol, provide detailed patient education (including a treatment summary and care plan), and serve as a single point of contact as patients move toward a treatment decision. Formal evaluation of the MPCC showed that patients were satisfied with this approach to the complex decision-making process in prostate cancer.

  11. "Theory Becoming Alive": The Learning Transition Process of Newly Graduated Nurses in Canada.

    Science.gov (United States)

    Nour, Violet; Williams, Anne M

    2018-01-01

    Background Newly graduated nurses often encounter a gap between theory and practice in clinical settings. Although this has been the focus of considerable research, little is known about the learning transition process. Purpose The purpose of this study was to explore the experiences of newly graduated nurses in acute healthcare settings within Canada. This study was conducted to gain a greater understanding of the experiences and challenges faced by graduates. Methods Grounded theory method was utilized with a sample of 14 registered nurses who were employed in acute-care settings. Data were collected using in-depth interviews. Constant comparative analysis was used to analyze data. Results Findings revealed a core category, "Theory Becoming Alive," and four supporting categories: Entry into Practice, Immersion, Committing, and Evolving. Theory Becoming Alive described the process of new graduate nurses' clinical learning experiences as well as the challenges that they encountered in clinical settings after graduating. Conclusions This research provides a greater understanding of learning process of new graduate nurses in Canada. It highlights the importance of providing supportive environments to assist new graduate nurses to develop confidence as independent registered nurses in clinical areas. Future research directions as well as supportive educational strategies are described.

  12. The lived experience of newly qualified radiographers (1950-1985): An oral history of radiography

    International Nuclear Information System (INIS)

    Decker, Sola

    2009-01-01

    The preparedness for practice of newly qualified healthcare professionals (including radiographers) has been the focus of attention in recent years as the practice environment continues to place great demands on its workforce. This paper reports an aspect of the findings from an oral history project on the career history of radiographers conducted as an academic research investigating the changes that have occurred in radiography and the impact these have had on the profession and the practice of radiography. The main focus of this paper is the lived experience of the informants of the oral history project as newly qualified radiographers. The findings are discussed in the context of current practice environment and developments in radiography. Analysis of the textual materials generated from informants' oral historical accounts, suggest radiographers trained in this time frame perceived their training as 'fit for purpose. The findings further suggest there is a general norm of 'get-on-with-it' as a coping strategy which is still prevalent in the profession today. The paper concludes by drawing on lessons that can be learned from the lived experiences of radiographers' oral historical accounts.

  13. Pedagogical Souvenirs: An Art Educator's Reflections on Field Trips as Professional Development

    Science.gov (United States)

    Kushins, Jodi

    2015-01-01

    This essay explores the nature and importance of field trips as sites for artistic development, intellectual fulfillment, and pedagogical inspiration. The author weaves personal reflections from a professional field trip and experience teaching art education online with creative and pedagogical references to make a case for experiential learning…

  14. Newly Discovered Ebola Virus Associated with Hemorrhagic Fever Outbreak in Uganda

    Science.gov (United States)

    Towner, Jonathan S.; Sealy, Tara K.; Khristova, Marina L.; Albariño, César G.; Conlan, Sean; Reeder, Serena A.; Quan, Phenix-Lan; Lipkin, W. Ian; Downing, Robert; Tappero, Jordan W.; Okware, Samuel; Lutwama, Julius; Bakamutumaho, Barnabas; Kayiwa, John; Comer, James A.; Rollin, Pierre E.; Ksiazek, Thomas G.; Nichol, Stuart T.

    2008-01-01

    Over the past 30 years, Zaire and Sudan ebolaviruses have been responsible for large hemorrhagic fever (HF) outbreaks with case fatalities ranging from 53% to 90%, while a third species, Côte d'Ivoire ebolavirus, caused a single non-fatal HF case. In November 2007, HF cases were reported in Bundibugyo District, Western Uganda. Laboratory investigation of the initial 29 suspect-case blood specimens by classic methods (antigen capture, IgM and IgG ELISA) and a recently developed random-primed pyrosequencing approach quickly identified this to be an Ebola HF outbreak associated with a newly discovered ebolavirus species (Bundibugyo ebolavirus) distantly related to the Côte d'Ivoire ebolavirus found in western Africa. Due to the sequence divergence of this new virus relative to all previously recognized ebolaviruses, these findings have important implications for design of future diagnostic assays to monitor Ebola HF disease in humans and animals, and ongoing efforts to develop effective antivirals and vaccines. PMID:19023410

  15. Development of new functional properties in traditional ceramics field

    International Nuclear Information System (INIS)

    Carda, J.B.; Pedra, J.M.; Nunez, I.; Peiro, N.C.; Gil, C.; Navarro, E.; Gomez, J.J.; Chiva, L.

    2004-01-01

    In the present communication, several ways to obtain functional properties in ceramic tiles will be exposed, developed by the research group in Solid State Chemistry of Jaume I University from Castellon, in close collaboration with the ceramic industry set in Castellon (Spain). Then, searching for a new properties, those that involve advanced fields in ceramics, such as mechanical, electrical or optical properties have been chosen, transferring their application to traditional products, selecting for it the development of this properties in surface (as the obtaining if glass-ceramic glazes) or in the ceramic body (increasing its mechanical resistance, more dense and with less thickness of layer). Related to the surface properties interesting in traditional ceramics field, glass-ceramic glazes have been designed, presenting high resistance to abrasion and chemical agents attack, formulating systems of devitrification of α-SiO 2 crystallization (cristobalite), anoritite and zircon. Systems that reduce resistivity of glazes have been developed too, causing the discharge to the ground of the static charge, designing a semiconductor system SnO 2 -Sb 2 O 3 . o finish with surface properties, bactericidal properties glazes have been originated, working with CeO 2 -ZrO 2 and TiO 2 (anatase) systems. According to ceramic bodies, highly gressificated systems have been developed, with an open porosity lower than 0.5% of water absorption and with high mechanical resistance, aspects that open ways to develop multilayer systems allowing the reduction of body thickness without a decrease of its technical features. (author)

  16. Design and development of a highly sensitive, field portable plasma source instrument for on-line liquid stream monitoring and real-time sample analysis

    International Nuclear Information System (INIS)

    Duan, Yixiang; Su, Yongxuan; Jin, Zhe; Abeln, Stephen P.

    2000-01-01

    The development of a highly sensitive, field portable, low-powered instrument for on-site, real-time liquid waste stream monitoring is described in this article. A series of factors such as system sensitivity and portability, plasma source, sample introduction, desolvation system, power supply, and the instrument configuration, were carefully considered in the design of the portable instrument. A newly designed, miniature, modified microwave plasma source was selected as the emission source for spectroscopy measurement, and an integrated small spectrometer with a charge-coupled device detector was installed for signal processing and detection. An innovative beam collection system with optical fibers was designed and used for emission signal collection. Microwave plasma can be sustained with various gases at relatively low power, and it possesses high detection capabilities for both metal and nonmetal pollutants, making it desirable to use for on-site, real-time, liquid waste stream monitoring. An effective in situ sampling system was coupled with a high efficiency desolvation device for direct-sampling liquid samples into the plasma. A portable computer control system is used for data processing. The new, integrated instrument can be easily used for on-site, real-time monitoring in the field. The system possesses a series of advantages, including high sensitivity for metal and nonmetal elements; in situ sampling; compact structure; low cost; and ease of operation and handling. These advantages will significantly overcome the limitations of previous monitoring techniques and make great contributions to environmental restoration and monitoring. (c)

  17. The Developing Field of Technology Education: A Review to Look Forward

    Science.gov (United States)

    Jones, Alister; Buntting, Cathy; de Vries, Marc J.

    2013-01-01

    This paper attempts to review the development of technology education over the last 20-25 years. The purpose is to reflect on how far the field has come and where it might go to, including what questions need to be considered in its ongoing development. The data for this paper draw on our work in developing "The International Handbook of Research…

  18. Cytological Evaluation and REBA HPV-ID HPV Testing of Newly Developed Liquid-Based Cytology, EASYPREP: Comparison with SurePath.

    Science.gov (United States)

    Lee, Youn Soo; Gong, Gyungyub; Sohn, Jin Hee; Ryu, Ki Sung; Lee, Jung Hun; Khang, Shin Kwang; Cho, Kyung-Ja; Kim, Yong-Man; Kang, Chang Suk

    2013-06-01

    The objective of this study was to evaluate a newly-developed EASYPREP liquid-based cytology method in cervicovaginal specimens and compare it with SurePath. Cervicovaginal specimens were prospectively collected from 1,000 patients with EASYPREP and SurePath. The specimens were first collected by brushing for SurePath and second for EASYPREP. The specimens of both methods were diagnosed according to the Bethesda System. Additionally, we performed to REBA HPV-ID genotyping and sequencing analysis for human papillomavirus (HPV) on 249 specimens. EASYPREP and SurePath showed even distribution of cells and were equal in cellularity and staining quality. The diagnostic agreement between the two methods was 96.5%. Based on the standard of SurePath, the sensitivity, specificity, positive predictive value, and negative predictive value of EASYPREP were 90.7%, 99.2%, 94.8%, and 98.5%, respectively. The positivity of REBA HPV-ID was 49.4% and 95.1% in normal and abnormal cytological samples, respectively. The result of REBA HPV-ID had high concordance with sequencing analysis. EASYPREP provided comparable results to SurePath in the diagnosis and staining quality of cytology examinations and in HPV testing with REBA HPV-ID. EASYPREP could be another LBC method choice for the cervicovaginal specimens. Additionally, REBA HPV-ID may be a useful method for HPV genotyping.

  19. Effect of Annealing Temperature on the Mechanical and Corrosion Behavior of a Newly Developed Novel Lean Duplex Stainless Steel.

    Science.gov (United States)

    Guo, Yanjun; Hu, Jincheng; Li, Jin; Jiang, Laizhu; Liu, Tianwei; Wu, Yanping

    2014-09-12

    The effect of annealing temperature (1000-1150 °C) on the microstructure evolution, mechanical properties, and pitting corrosion behavior of a newly developed novel lean duplex stainless steel with 20.53Cr-3.45Mn-2.08Ni-0.17N-0.31Mo was studied by means of optical metallographic microscopy (OMM), scanning electron microscopy (SEM), magnetic force microscopy (MFM), scanning Kelvin probe force microscopy (SKPFM), energy dispersive X-ray spectroscopy (EDS), uniaxial tensile tests (UTT), and potentiostatic critical pitting temperature (CPT). The results showed that tensile and yield strength, as well as the pitting corrosion resistance, could be degraded with annealing temperature increasing from 1000 up to 1150 °C. Meanwhile, the elongation at break reached the maximum of 52.7% after annealing at 1050 °C due to the effect of martensite transformation induced plasticity (TRIP). The localized pitting attack preferentially occurred at ferrite phase, indicating that the ferrite phase had inferior pitting corrosion resistance as compared to the austenite phase. With increasing annealing temperature, the pitting resistance equivalent number (PREN) of ferrite phase dropped, while that of the austenite phase rose. Additionally, it was found that ferrite possessed a lower Volta potential than austenite phase. Moreover, the Volta potential difference between ferrite and austenite increased with the annealing temperature, which was well consistent with the difference of PREN.

  20. Experimental investigation for determination of optimal X-ray beam tube voltages in a newly developed digital breast tomosynthesis system

    Energy Technology Data Exchange (ETDEWEB)

    Park, Hye-Suk, E-mail: radiosugar@yonsei.ac.kr [Department of Radiological Science and Research Institute of Health Science, Yonsei University, Wonju, Gangwon 220-710 (Korea, Republic of); Kim, Ye-Seul, E-mail: radiohesugar@gmail.com [Department of Radiological Science and Research Institute of Health Science, Yonsei University, Wonju, Gangwon 220-710 (Korea, Republic of); Choi, Young-Wook, E-mail: ywchoi@keri.re.kr [Korea Electrotechnology Research Institute (KERI), Ansan, Geongki 426-170 (Korea, Republic of); Choi, JaeGu, E-mail: jgchoi88@paran.com [Korea Electrotechnology Research Institute (KERI), Ansan, Geongki 426-170 (Korea, Republic of); Rhee, Yong-Chun, E-mail: ycrhee@yonsei.ac.kr [Department of Radiological Science and Research Institute of Health Science, Yonsei University, Wonju, Gangwon 220-710 (Korea, Republic of); Kim, Hee-Joung, E-mail: hjk1@yonsei.ac.kr [Department of Radiological Science and Research Institute of Health Science, Yonsei University, Wonju, Gangwon 220-710 (Korea, Republic of)

    2014-11-01

    Our purpose was to investigate optimal tube voltages (kVp) for a newly developed digital breast tomosynthesis (DBT) process and to determine tube current–exposure time products (mA s) for the average glandular dose (AGD), which is similar to that of the two views in conventional mammography (CM). In addition, the optimal acquisition parameters for this system were compared with those of CM. The analysis was based on the contrast-to-noise ratio (CNR) from the simulated micro-calcifications on homogeneous phantoms, and the figure of merit (FOM) was retrieved from the CNR and AGD at X-ray tube voltages ranging from 24 to 40 kVp at intervals of 2 kV. The optimal kVp increased more than 2 kV with increasing glandularity for thicker (≥50 mm) breast phantoms. The optimal kVp for DBT was found to be 4–7 kV higher than that calculated for CM with breast phantoms thicker than 50 mm. This is likely due to the greater effect of noise and dose reduction by kVp increment when using the lower dose per projection in DBT. It is important to determine optimum acquisition conditions for a maximally effective DBT system. The results of our study provide useful information to further improve DBT for high quality imaging.

  1. Development of High Field MR Imaging and Spectroscopy Techniques of the Prostate

    NARCIS (Netherlands)

    Arteaga de Castro, C.S.

    2013-01-01

    This thesis summarizes the work of the development of new techniques for obtaining magnetic resonance imaging (MRI) and spectroscopy (MRS) of the prostate at the ultra high field of 7 tesla (T). The 7 T field strength presents various challenges such as the shortening of the wavelength and the lower

  2. [Psycho-social factors of sexual failure among newly married Uyghur young males].

    Science.gov (United States)

    Erkin, Ashim; Hamrajan, Memtili; Kadirjan, Mijit; Adil, Eli; Elijan, Abdureshit; Ibrahim, Ubul; Abdulla, Tursun; Hasanjan, Abdurehim; Turgun, Hekim; Eli, Ablet; Eset, Metmusa

    2016-08-01

    To study the psycho-social risk factors of sexual failure among newly married young males in the Uyghur population. We conducted a paired case control study of 186 newly married Uyghur young males (aged 17-30 [23.4±2.9] yr) with sexual failure and another 186 (aged 18-34 [24.0±3.1] yr) with no such problem as controls. We performed a logistic regression analysis on the possible psycho-social risk factors of this condition. Logistic regression analysis showed that the risk factors of sexual failure among the newly married men included personality (OR=0.271, 95% CI 0.176-0.420), income (OR=0.391, 95% CI 0.264-0.580), history of masturbation (OR=0.824, 95% CI 0.710-0.956), premarital sex (OR=0.757, 95% CI 0.677-0.847), sense of obligation (OR=1.756, 95% CI 1.157-2.693), equality of the social status (OR=0.574, 95% CI 0.435-0.756), degree of mutual care (OR=1.605, 95% CI 1.268-2.032), female's psychological obstacle (OR=2.832, 95% CI 1.221-6.569), and religion (OR=0.643, 95% CI 0.472-0.967). There was a statistical significance in the correlation between these factors and sexual failure in the newly married males (all Ppsycho-social factors, which necessitates sexual education among young males and particularly pre-marriage sexual education and psychological guide among both males and females.

  3. The Alexandria library, a quantum-chemical database of molecular properties for force field development.

    Science.gov (United States)

    Ghahremanpour, Mohammad M; van Maaren, Paul J; van der Spoel, David

    2018-04-10

    Data quality as well as library size are crucial issues for force field development. In order to predict molecular properties in a large chemical space, the foundation to build force fields on needs to encompass a large variety of chemical compounds. The tabulated molecular physicochemical properties also need to be accurate. Due to the limited transparency in data used for development of existing force fields it is hard to establish data quality and reusability is low. This paper presents the Alexandria library as an open and freely accessible database of optimized molecular geometries, frequencies, electrostatic moments up to the hexadecupole, electrostatic potential, polarizabilities, and thermochemistry, obtained from quantum chemistry calculations for 2704 compounds. Values are tabulated and where available compared to experimental data. This library can assist systematic development and training of empirical force fields for a broad range of molecules.

  4. The Alexandria library, a quantum-chemical database of molecular properties for force field development

    Science.gov (United States)

    Ghahremanpour, Mohammad M.; van Maaren, Paul J.; van der Spoel, David

    2018-04-01

    Data quality as well as library size are crucial issues for force field development. In order to predict molecular properties in a large chemical space, the foundation to build force fields on needs to encompass a large variety of chemical compounds. The tabulated molecular physicochemical properties also need to be accurate. Due to the limited transparency in data used for development of existing force fields it is hard to establish data quality and reusability is low. This paper presents the Alexandria library as an open and freely accessible database of optimized molecular geometries, frequencies, electrostatic moments up to the hexadecupole, electrostatic potential, polarizabilities, and thermochemistry, obtained from quantum chemistry calculations for 2704 compounds. Values are tabulated and where available compared to experimental data. This library can assist systematic development and training of empirical force fields for a broad range of molecules.

  5. Three newly recorded Linyphiid spiders (Araneae: Linyphiidae from Korea

    Directory of Open Access Journals (Sweden)

    Sue Yeon Lee

    2018-03-01

    Full Text Available Three Linyphiid spiders, Caviphantes pseudosaxetorum Wunderlich, 1979, Erigone edentata Saito and Ono, 2001, and Savignia kawachiensis Oi, 1960, are reported for the first time from Korea with taxonomic illustrations and redescription. In this study, the genus Caviphantes Oi, 1960 is also newly recorded to Korean spider fauna.

  6. Testing a newly developed single-sphere neutron spectrometer in reference monochromatic fields from 147 keV to 14.8 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Bedogni, R., E-mail: roberto.bedogni@lnf.infn.it [INFN—LNF Laboratori Nazionali di Frascati, Via E. Fermi n. 40, 00044 Frascati (Italy); Gómez-Ros, J.M. [INFN—LNF Laboratori Nazionali di Frascati, Via E. Fermi n. 40, 00044 Frascati (Italy); CIEMAT, Av. Complutense 40, 28040 Madrid (Spain); Pola, A.; Introini, M.V. [Politecnico di Milano - Dipartimento di Energia, Via Ponzio 34/3, 20133 Milano (Italy); Bortot, D. [INFN—LNF Laboratori Nazionali di Frascati, Via E. Fermi n. 40, 00044 Frascati (Italy); Politecnico di Milano - Dipartimento di Energia, Via Ponzio 34/3, 20133 Milano (Italy); Gentile, A.; Esposito, A.; Mazzitelli, G.; Buonomo, B.; Quintieri, L.; Foggetta, L. [INFN—LNF Laboratori Nazionali di Frascati, Via E. Fermi n. 40, 00044 Frascati (Italy)

    2013-06-21

    A new neutron spectrometer, designed to simultaneously respond from the thermal domain up to hundreds of MeV neutrons, was designed and built in the framework of the INFN project NESCOFI@BTF. It has been called SP{sup 2} (SPherical SPectrometer) and it consists of 31 thermal neutron detectors embedded in a 25 cm diameter polyethylene sphere with an internal 1 cm thick lead shell. The new spectrometer shows similar performance as the Bonner sphere spectrometer, but has the notable advantage of requiring only one exposure to determine the whole spectrum. The SP{sup 2} response matrix, previously calculated with MCNP, has been experimentally evaluated with monochromatic reference neutron fields from 147 keV to 14.8 MeV at PTB Braunschweig. As suitable thermal neutron detectors, Dysprosium activation foils were adopted at this stage. The results of the experiment confirmed the correctness of the response matrix within an overall uncertainty of ±3%. The next phase of the NESCOFI@BTF project will be the replacement of passive detectors with active counters, thus leading to a real-time spectrometric monitor that is expected to significantly innovate the neutron control task in neutron-producing facilities, such as the beam-lines for industrial irradiation or condensed matter studies.

  7. [Impact of Increased Supply of Newly Licensed Nurses on Hospital Nurse Staffing and Policy Implications].

    Science.gov (United States)

    Kim, Yunmi; You, Sunju; Kim, Jinhyun

    2017-12-01

    This study aimed to analyze the impact of increasing the supply of newly licensed nurses on improving the hospital nurse staffing grades for the period of 2009~2014. Using public administrative data, we analyzed the effect of newly licensed nurses on staffing in 1,594 hospitals using Generalized Estimating Equation (GEE) ordered logistic regression, and of supply variation on improving staffing grades in 1,042 hospitals using GEE logistic regression. An increase of one newly licensed nurse per 100 beds in general units had significantly lower odds of improving staffing grades (grades 6~0 vs. 7) (odds ratio=0.95, p=.005). The supply of newly licensed nurses increased by 32% from 2009 to 2014, and proportion of hospitals whose staffing grade had improved, not changed, and worsened was 19.1%, 70.1%, and 10.8% respectively. Compared to 2009, the supply variation of newly licensed nurses in 2014 was not significantly related to the increased odds of improving staffing grades in the region (OR=1.02, p=.870). To achieve a balance in the regional supply and demand for hospital nurses, compliance with nurse staffing legislation and revisions in the nursing fee differentiation policy are needed. Rather than relying on increasing nurse supply, retention policies for new graduate nurses are required to build and sustain competent nurse workforce in the future. © 2017 Korean Society of Nursing Science

  8. Pilot Implementation: Learning from Field Tests in IS Development

    DEFF Research Database (Denmark)

    Herzum, Morten; Bansler, Jørgen P.; Havn, Erling C.

    2012-01-01

    the laboratory to the field, thereby allowing users to experience a system design under realistic conditions and developers to get feedback from realistic use while the design is still malleable. We characterize pilot implementation, contrast it with prototyping, propose a fiveelement model of pilot...... implementation and provide three empirical illustrations of our model. We conclude that pilot implementation has much merit as an ISD technique when system performance is contingent on context. But we also warn developers that, despite their seductive conceptual simplicity, pilot implementations can be difficult...

  9. Feasibility and effects of newly developed balance control trainer for mobility and balance in chronic stroke patients: a randomized controlled trial.

    Science.gov (United States)

    Lee, So Hyun; Byun, Seung Deuk; Kim, Chul Hyun; Go, Jin Young; Nam, Hyeon Uk; Huh, Jin Seok; Jung, Tae Du

    2012-08-01

    To investigate the feasibility and effects of balance training with a newly developed Balance Control Trainer (BCT) that applied the concept of vertical movement for the improvements of mobility and balance in chronic stroke patients. Forty chronic stroke patients were randomly assigned to an experimental or a control group. The experimental group (n=20) underwent training with a BCT for 20 minutes a day, 5 days a week for 4 weeks, in addition to concurrent conventional physical therapy. The control group (n=20) underwent only conventional therapy for 4 weeks. All participants were assessed by: the Functional Ambulation Categories (FAC), 10-meter Walking Test (10mWT), Timed Up and Go test (TUG), Berg Balance Scale (BBS), Korean Modified Barthel Index (MBI), and Manual Muscle Test (MMT) before training, and at 2 and 4 weeks of training. There were statistically significant improvements in all parameters except knee extensor power at 2 weeks of treatment, and in all parameters except MBI which showed further statistically significant progress in the experimental group over the next two weeks (pgait in ambulatory chronic stroke patients. Furthermore, it may provide additional benefits when used in conjunction with conventional therapies.

  10. Hope in newly diagnosed cancer patients.

    Science.gov (United States)

    Duggleby, Wendy; Ghosh, Sunita; Cooper, Dan; Dwernychuk, Lynne

    2013-11-01

    Hope is important to cancer patients as it helps them deal with their diagnosis. Little is known about hope in newly diagnosed cancer patients. Based on the Transcending Possibilities conceptual model of hope, the purpose of this study was to examine the relationship of hope with pain, energy, and psychological and demographic characteristics in newly diagnosed adult oncology outpatients. Data from 310 New Patient Assessment Forms from cancer outpatients' health records were collected. Health records from the first six months of 2009 were reviewed and data were collected on hope, energy, pain, depression, anxiety, feeling overwhelmed, and demographic variables. A generalized linear modeling approach was used to study the relationship of hope scores with these variables. Hypothesized variables and variables that were significant at the P = 0.01 level from the univariate analysis were entered into the multivariate model, with hope scores as the dependent variable. Hope scores were significantly negatively related to age (P = 0.02). More specifically, oncology patients who were 65 years of age or older had significantly less hope than those under the age of 65 years (P = 0.01). Gender (P = 0.009) also was a significant factor, with men having higher hope scores than women. No other variables were significant. Older adults comprise the majority of persons in Canada with cancer. The lower hope scores found in this age group compared with their younger counterparts underscore the importance of further research. This study provides a foundation for future research in this important area for oncology patients. Copyright © 2013 U.S. Cancer Pain Relief Committee. Published by Elsevier Inc. All rights reserved.

  11. Different Pathophysiological Phenotypes among Newly Diagnosed Type 2 Diabetes Patients

    DEFF Research Database (Denmark)

    Stidsen, Jacob

    2013-01-01

    Type 2 diabetes (T2D) can be considered a syndrome with several different pathophysiological mechanisms leading to hyperglycemia. Nonetheless, T2D is treated according to algorithms as if it was one disease entity. Methods: We investigated the prevalence of different pathophysiological phenotypes...... or secondary diabetes), classic obesity-associated insulin resistant diabetes ( f-P-C-peptide >= 568 pmol/l) and a normoinsulinopenic group (333 age of our new T2D patients was 61 years (range 21-95 years), 57% were men. We found that 3.0% newly diagnosed T2D patients...... suffered from LADA, 3.9% from secondary diabetes, 6.0% from steroid induced diabetes 5.9% had insulinopenic diabetes, whereas 56.7% presented the classic obesity-associated insulin-resistant phenotype. 24.6% was classified as normoinsulinopenic patients. Conclusion: We conclude that newly diagnosed T2D...

  12. Development of transient internal probe (TIP) magnetic field diagnostic

    International Nuclear Information System (INIS)

    Galambos, J.P.; Bohnet, M.A.; Jarboe, T.R.; Mattick, A.T.

    1994-01-01

    The Transient Internal Probe (TIP) is designed to permit measurement of internal magnetic fields, in hot, high density plasmas. The concept consists of accelerating a probe to high velocities (2.2 Km/s) in order to minimize probe exposure time to plasma. Faraday rotation within the probe is used to measure the local magnetic field. An Argon laser illuminates the probe consisting of a Faraday-rotator material with a retro-reflector that returns the incident light to the detection system. Performance results of the light gas gun and optical detection system will be shown. To date, the gas gun has been extensively tested consistently achieving velocities between 2 and 3 km/s. The probe and detection scheme have been tested by dropping the probe through a static magnetic field. Magnetic field resolution of 20 gauss and spatial resolution of 5 mm has been achieved. System frequency response is 10Mhz. Work is currently being conducted to integrate the diagnostic system with laboratory plasma experiments. Specifically a gas interfaced system has been developed to prevent helium muzzle gas from entering the plasma chamber with the probe. Additionally the probe must be separated from the sabot which protects the probe during acceleration in the gas gun. Data will be presented showing the results of various separation techniques

  13. On the Use of Safety Certification Practices in Autonomous Field Robot Software Development

    DEFF Research Database (Denmark)

    Mogensen, Johann Thor Ingibergsson; Schultz, Ulrik Pagh; Kuhrmann, Marco

    2015-01-01

    reactions or performance in malfunctioning systems, and influence industry regarding software development and project management. However, academia seemingly did not reach the same degree of utilisation of standards. This paper presents the findings from a systematic mapping study in which we study...... the state-of-the-art in developing software for safety-critical software for autonomous field robots. The purpose of the study is to identify practices used for the development of autonomous field robots and how these practices relate to available safety standards. Our findings from reviewing 49 papers show...... on the quest for suitable approaches to develop safety-critical software, awaiting appropriate standards for this support....

  14. Special features in choosing a development procedure for deep gas condensate fields with small reserves

    Energy Technology Data Exchange (ETDEWEB)

    Rassokhin, G V; Soshnin, N M

    1971-01-01

    In planning the development and production schedule for fields with small gas-condensate reserves, the following factors need to be considered: capital investment per unit of production, value of produced gas, ultimate recovered reserves, geological structure of the field, depth of well, heterogeneity of producing sands, etc. The importance of such factors is discussed and it is shown that for small fields, the parameter of minimum net expense cannot be used as a planning tool. Both geological and economic factors must be included in field development.

  15. Higher incidence of hip fracture in newly diagnosed schizophrenic ...

    African Journals Online (AJOL)

    Higher incidence of hip fracture in newly diagnosed schizophrenic patients in Taiwan. Hip fracture is a major public health concern due to its poor outcome and serious socioeconomic burden in older people (1). Evidence has shown that many factors are related to increased risk of hip fracture, but psychiatric diseases are ...

  16. Death Concerns among Individuals Newly Diagnosed with Lung Cancer

    Science.gov (United States)

    Lehto, Rebecca; Therrien, Barbara

    2010-01-01

    Confronting the reality of death is an important challenge for individuals facing life-threatening illness such as lung cancer, the leading cause of cancer death. Few studies, however, document the nature of death-related concerns in individuals newly diagnosed with lung cancer. The aims of this exploratory study were to examine unsolicited…

  17. Development of a Kirkpatrick-Baez microscope with a large visual field

    International Nuclear Information System (INIS)

    Kodama, R.; Ikeda, N.; Kato, Y.

    1995-01-01

    The authors have developed an advanced Kirkpatrick-Baez (AKB) microscope to diagnose a laser-produced-plasma. The AKB microscope optics are two pairs of hyperbolical and elliptical cylindrical-mirrors to avoid a spherical aberration and field obliquity. Ray trace calculation was applied to optimize the characterization. The microscope has attained a spatial resolution of less than 3 mm at 2.5-keV x-ray in the field of 800 mm from experiments

  18. Patients with newly diagnosed Rheumatoid Arthritis are at increased risk of Diabetes Mellitus

    DEFF Research Database (Denmark)

    Emamifar, Amir; Levin, Klaus; Jensen Hansen, Inger Marie

    2018-01-01

    -C-reactive protein (DAS28-CRP) at the time of diagnosis and after 4 months (±1-2 months) of treatment initiation were extracted from Danbio Registry. To reveal the presence of DM, patients' electronic medical records were reviewed. The prevalence of DM in our patients was compared (using an age- and gender......-matched analysis) with that expected from Danish population. RESULTS: of 439 included patients, 60.1% were female, mean of age 64.6±15.0 years and RA disease duration 2.6±1.7 years. Prevalence of DM was 57/439 (12.9%), herein type II DM 52 (91.2%) and type I DM 5 (8.8%). Except for two patients, diagnosis of DM......AIMS: To reveal the prevalence of Diabetes Mellitus (DM) in patients with newly diagnosed Rheumatoid Arthritis (RA) and evaluate the association between clinical characteristics of RA and DM as well as treatment response in newly diagnosed RA patients with DM. METHODS: Newly diagnosed, adult, RA...

  19. Changes in immunological status among newly-diagnosed HIV-infected in Denmark 1995-2005

    DEFF Research Database (Denmark)

    Hoegh, S.; Lohse, N.; Hansen, A.B.

    2008-01-01

    INTRODUCTION: The incidence of new HIV diagnoses in Denmark has remained stable since 1991, but it has increased among the subgroup of homosexual men in recent years. This may reflect an actual increase in newly infected, e.g. as a result of increased risk behaviour, or it may reflect increased HIV....... MATERIALS AND METHODS: Observational study based on the Danish HIV Cohort Study, which includes all adults seen at Danish HIV clinics since 1995. RESULTS: From 2000 to 2004 the number of newly-infected homosexual men increased (from 69 to 123), particularly in persons under 30 years (from 5 to 42......). The median CD4 cell count at the time of diagnosis increased in this group (median 19.1 cells/microL per year [95% CI: 3.7-11.3]), while it remained stable among heterosexually infected. The number of newly-diagnosed homosexually infected under 30 years with a CD4 cell count over 400 cells/microL increased...

  20. Relationships between gas field development and the presence and abundance of pygmy rabbits in southwestern Wyoming

    Science.gov (United States)

    Germaine, Stephen; Carter, Sarah; Ignizio, Drew A.; Freeman, Aaron T.

    2017-01-01

    More than 5957 km2 in southwestern Wyoming is currently covered by operational gas fields, and further development is projected through 2030. Gas fields fragment landscapes through conversion of native vegetation to roads, well pads, pipeline corridors, and other infrastructure elements. The sagebrush steppe landscape where most of this development is occurring harbors 24 sagebrush-associated species of greatest conservation need, but the effects of gas energy development on most of these species are unknown. Pygmy rabbits (Brachylagus idahoensis) are one such species. In 2011, we began collecting three years of survey data to examine the relationship between gas field development density and pygmy rabbit site occupancy patterns on four major Wyoming gas fields (Continental Divide–Creston–Blue Gap, Jonah, Moxa Arch, Pinedale Anticline Project Area). We surveyed 120 plots across four gas fields, with plots distributed across the density gradient of gas well pads on each field. In a 1 km radius around the center of each plot, we measured the area covered by each of 10 gas field infrastructure elements and by shrub cover using 2012 National Agriculture Imagery Program imagery. We then modeled the relationship between gas field elements, pygmy rabbit presence, and two indices of pygmy rabbit abundance. Gas field infrastructure elements—specifically buried utility corridors and a complex of gas well pads, adjacent disturbed areas, and well pad access roads—were negatively correlated with pygmy rabbit presence and abundance indices, with sharp declines apparent after approximately 2% of the area consisted of gas field infrastructure. We conclude that pygmy rabbits in southwestern Wyoming may be sensitive to gas field development at levels similar to those observed for greater sage-grouse, and may suffer local population declines at lower levels of development than are allowed in existing plans and policies designed to conserve greater sage-grouse by limiting

  1. Development ethics - Why? What? How? A formulation of the field

    NARCIS (Netherlands)

    D.R. Gasper (Des)

    2012-01-01

    textabstractThe paper assesses the rationale, contributions, structure, and challenges of the field of development ethics. Processes of social and economic transformation involve great risks and costs and great opportunities for gain, but the benefits, costs, and risks are typically hugely unevenly

  2. Field Sample Preparation Method Development for Isotope Ratio Mass Spectrometry

    International Nuclear Information System (INIS)

    Leibman, C.; Weisbrod, K.; Yoshida, T.

    2015-01-01

    Non-proliferation and International Security (NA-241) established a working group of researchers from Los Alamos National Laboratory (LANL), Pacific Northwest National Laboratory (PNNL) and Savannah River National Laboratory (SRNL) to evaluate the utilization of in-field mass spectrometry for safeguards applications. The survey of commercial off-the-shelf (COTS) mass spectrometers (MS) revealed no instrumentation existed capable of meeting all the potential safeguards requirements for performance, portability, and ease of use. Additionally, fieldable instruments are unlikely to meet the International Target Values (ITVs) for accuracy and precision for isotope ratio measurements achieved with laboratory methods. The major gaps identified for in-field actinide isotope ratio analysis were in the areas of: 1. sample preparation and/or sample introduction, 2. size reduction of mass analyzers and ionization sources, 3. system automation, and 4. decreased system cost. Development work in 2 through 4, numerated above continues, in the private and public sector. LANL is focusing on developing sample preparation/sample introduction methods for use with the different sample types anticipated for safeguard applications. Addressing sample handling and sample preparation methods for MS analysis will enable use of new MS instrumentation as it becomes commercially available. As one example, we have developed a rapid, sample preparation method for dissolution of uranium and plutonium oxides using ammonium bifluoride (ABF). ABF is a significantly safer and faster alternative to digestion with boiling combinations of highly concentrated mineral acids. Actinides digested with ABF yield fluorides, which can then be analyzed directly or chemically converted and separated using established column chromatography techniques as needed prior to isotope analysis. The reagent volumes and the sample processing steps associated with ABF sample digestion lend themselves to automation and field

  3. Use of passive alpha detectors to screen for uranium contamination in a field at Fernald, Ohio

    International Nuclear Information System (INIS)

    Dudney, C.S.; Meyer, K.E.; Gammage, R.B.; Wheeler, R.V.; Salasky, M.; Kotrappa, P.

    1995-01-01

    This paper reports the results from a field test of newly developed techniques for inexpensive, in situ screening of soil for alpha contamination. Passive alpha detectors that are commercially available for the detection indoor airborne alpha activity (i.e., 222 Rn) have been modified so they can be applied to the detection of alpha contamination on surfaces or in soils. Results reported here are from an intercomparison involving several different techniques with all measurements being made at the same sites in a field near the formerly used uranium processing facility at Fernald, Ohio, during the summer of 1994. The results for two types of passive alpha detector show that the quality of calibration is improved if soils samples are milled to increase homogeneity within the soil matrices. The correlation between laboratory based radiochemical analyses and quick, field-based screening measurements is acceptable and can be improved if the passive devices are left for longer exposure times in the field. The total cost per measurement for either type of passive alpha detector is probably less than $25 and should provide a cost-effective means for site managers to develop the information needed to find areas with remaining alpha contamination so resources can be allocated efficiently

  4. Study on mid and long-term strategic plan formulation for newly-constructed NPP

    International Nuclear Information System (INIS)

    Song Lin

    2014-01-01

    Mid and Long-term strategic plan plays a key role for the management of a newly constructed nuclear power company. Among others, process, goals, and risk management, are the primary concerns during plan preparing. The article analyzed these three areas for Fuqing NPP, including the formulating process for the plan, the mid and long-term goal setting of the company, the major risk analysis and countermeasure selection therefore. Through that solutions and suggestions for strategic plan formulation were concluded for newly-constructed NPP. (author)

  5. Development of a gas-phase field ionization ion source

    International Nuclear Information System (INIS)

    Allan, G.L.; Legge, G.J.F.

    1983-01-01

    A field ionization ion source has been developed to investigate the suitability of using such a source with the Melbourne Proton Microprobe. Operating parameters have been measured, and the source has been found to be brighter than the radiofrequency ion source presently used in the Melbourne 5U Pelletron Accelerator. Improvements to the source geometry to increase the current output are planned

  6. Development of a nonresonant perturbation technique and its application to multicell traveling-wave deflectors

    Energy Technology Data Exchange (ETDEWEB)

    Tan, Jianhao [Shanghai Institute of Applied Physics, Chinese Academy of Science, Shanghai 201800 (China); Shanghai Science Research Center, Chinese Academy of Science, Shanghai 201204 (China); Tong, Dechun [Department of Engineering Physics, Tsinghua University, Beijing 100084 (China); Gu, Qiang; Fang, Wencheng [Shanghai Institute of Applied Physics, Chinese Academy of Science, Shanghai 201800 (China); Shanghai Science Research Center, Chinese Academy of Science, Shanghai 201204 (China); Zhao, Zhentang, E-mail: zhaozhentang@sinap.ac.cn [Shanghai Institute of Applied Physics, Chinese Academy of Science, Shanghai 201800 (China); Shanghai Key Laboratory of Cryogenics & Superconducting RF Technology, Shanghai 201800 (China); Shanghai Science Research Center, Chinese Academy of Science, Shanghai 201204 (China)

    2016-11-01

    A tuning method augmented by the bead-pull technique based on nonresonant perturbation field distribution measurements has been widely applied for traveling-wave (TW) accelerating structures. The method is also suitable for deflecting structures, but some key considerations of the field components of the HEM{sub 11} mode and the selection of bead merit discussion. A “cage”-type perturbing object has been designed, fabricated and applied in nonresonant perturbation measurements. Measurements on an S-band TW deflecting structure are carried out, and the measurement and tuning method will be used on the newly developed X-band deflecting structure at Shanghai Institute of Applied Physics.

  7. Development of a nonresonant perturbation technique and its application to multicell traveling-wave deflectors

    International Nuclear Information System (INIS)

    Tan, Jianhao; Tong, Dechun; Gu, Qiang; Fang, Wencheng; Zhao, Zhentang

    2016-01-01

    A tuning method augmented by the bead-pull technique based on nonresonant perturbation field distribution measurements has been widely applied for traveling-wave (TW) accelerating structures. The method is also suitable for deflecting structures, but some key considerations of the field components of the HEM_1_1 mode and the selection of bead merit discussion. A “cage”-type perturbing object has been designed, fabricated and applied in nonresonant perturbation measurements. Measurements on an S-band TW deflecting structure are carried out, and the measurement and tuning method will be used on the newly developed X-band deflecting structure at Shanghai Institute of Applied Physics.

  8. PERFORMANCE OF NEWLY CONFIGURED SUBMERGED MEMBRANE BIOREACTOR FOR AEROBIC INDUSTRIAL WASTEWATER TREATMENT

    Directory of Open Access Journals (Sweden)

    I Gede Wenten

    2012-02-01

    Full Text Available The application of membrane to replace secondary clarifier of conventional activated sludge, known as membrane bioreactor, has led to a small footprint size of treatment with excellent effluent quality. The use of MBR eliminates almost all disadvantages encountered in conventional wastewater treatment plant such as low biomass concentration and washout of fine suspended solids. However, fouling remains as a main drawback. To minimize membrane fouling, a new configuration of submerged membrane bioreactor for aerobic industrial wastewater treatment has been developed. For the new configuration, a bed of porous particle is applied to cover the submerged ends-free mounted ultrafiltration membrane. Membrane performance was assessed based on flux productivity and selectivity. By using tapioca wastewater containing high organic matter as feed solution, reasonably high and stable fluxes around 11 l/m2.h were achieved with COD removal efficiency of more than 99%. The fouling analysis also shows that the newly configured ends-free membrane bioreactor exhibits lower irreversible resistance compared with the submerged one. In addition, the performance of pilot scale system, using a membrane module  with 10 m2 effective area and reactor tank with 120 L volume, was also assessed. The flux achieved from the pilot scale system around 8 l/m2.h with COD removal of more than 99%. Hence, this study has demonstrated the feasibility of the newly configured submerged ends-free MBR at larger scale.

  9. ‘BRICS without straw’? A systematic literature review of newly emerging economies’ influence in global health

    Science.gov (United States)

    2013-01-01

    Background Since 2010, five newly emerging economies collectively known as ‘BRICS’ (Brazil, India, Russia, China and South Africa) have caught the imagination, and scholarly attention, of political scientists, economists and development specialists. The prospect of a unified geopolitical bloc, consciously seeking to re-frame international (and global) health development with a new set of ideas and values, has also, if belatedly, begun to attract the attention of the global health community. But what influence, if any, do the BRICS wield in global health, and, if they do wield influence, how has that influence been conceptualized and recorded in the literature? Methods We conducted a systematic literature review in (March-December 2012) of documents retrieved from the databases EMBASE, PubMed/Medline, Global Health, and Google Scholar, and the websites of relevant international organisations, research institutions and philanthropic organisations. The results were synthesised using a framework of influence developed for the review from the political science literature. Results Our initial search of databases and websites yielded 887 documents. Exclusion criteria narrowed the number of documents to 71 journal articles and 23 reports. Two researchers using an agreed set of inclusion criteria independently screened the 94 documents, leaving just 7 documents. We found just one document that provided sustained analysis of the BRICS’ collective influence; the overwhelming tendency was to describe individual BRICS countries influence. Although influence was predominantly framed by BRICS countries’ material capability, there were examples of institutional and ideational influence - particularly from Brazil. Individual BRICS countries were primarily ‘opportunity seekers’ and region mobilisers but with potential to become ‘issue leaders’ and region organisers. Conclusion Though small in number, the written output on BRICS influence in global health has

  10. Maintaining Professional Commitment as a Newly Credentialed Athletic Trainer in the Secondary School Setting.

    Science.gov (United States)

    Mazerolle, Stephanie M; Myers, Sarah L; Walker, Stacy E; Kirby, Jessica

    2018-03-01

      Professional commitment, or one's affinity and loyalty to a career, has become a topic of interest in athletic training. The expanding research on the topic, however, has omitted newly credentialed athletic trainers (ATs). For an impressionable group of practitioners, transitioning to clinical practice can be stressful.   To explore the professional commitment of newly credentialed ATs in the secondary school setting.   Secondary school.   Qualitative study.   A total of 31 newly credentialed ATs (6 men, 25 women; mean age = 24 ± 3 years) participated. Of these, 17 ATs (4 men, 13 women; mean age = 25 ± 4 years) were employed full time in the secondary school setting, and 14 ATs (2 men, 12 women; mean age = 23.0 ± 2.0 years) were graduate assistant students in the secondary school setting.   All participants completed semistructured interviews, which focused on their experiences in the secondary school setting and transitioning into the role and setting. Transcripts were analyzed using the phenomenologic approach. Creditability was established by peer review, member checks, and researcher triangulation.   Four main findings related to the professional commitment of newly credentialed ATs in the secondary school setting were identified. Work-life balance, professional relationships formed with the student-athletes, enjoyment gained from working in the secondary school setting, and professional responsibility emerged as factors facilitating commitment.   Affective commitment is a primary facilitator of professional commitment. Newly credentialed ATs who enjoy their jobs and have time to engage in nonwork roles are able to maintain a positive professional commitment. Our findings align with the previous literature and help strengthen our understanding that rejuvenation and passion are important to professional commitment.

  11. Development of the field of structural physiology

    Science.gov (United States)

    FUJIYOSHI, Yoshinori

    2015-01-01

    Electron crystallography is especially useful for studying the structure and function of membrane proteins — key molecules with important functions in neural and other cells. Electron crystallography is now an established technique for analyzing the structures of membrane proteins in lipid bilayers that closely simulate their natural biological environment. Utilizing cryo-electron microscopes with helium-cooled specimen stages that were developed through a personal motivation to understand the functions of neural systems from a structural point of view, the structures of membrane proteins can be analyzed at a higher than 3 Å resolution. This review covers four objectives. First, I introduce the new research field of structural physiology. Second, I recount some of the struggles involved in developing cryo-electron microscopes. Third, I review the structural and functional analyses of membrane proteins mainly by electron crystallography using cryo-electron microscopes. Finally, I discuss multifunctional channels named “adhennels” based on structures analyzed using electron and X-ray crystallography. PMID:26560835

  12. Degradation of dibenzofuran via multiple dioxygenation by a newly isolated Agrobacterium sp. PH-08.

    Science.gov (United States)

    Le, T T; Murugesan, K; Nam, I-H; Jeon, J-R; Chang, Y-S

    2014-03-01

    To demonstrate the biodegradation of dibenzofuran (DF) and its structural analogs by a newly isolated Agrobacterium sp. PH-08. To assess the biodegradation potential of newly isolated Agrobacterium sp. PH-08, various substrates were evaluated as sole carbon sources in growth and biotransformation experiments. ESI LC-MS/MS analysis revealed the presence of angular degrading by-products as well as lateral dioxygenation metabolites in the upper pathway. The metabolites in the lower pathway also were detected. In addition, the cometabolically degraded daughter compounds of DF-related compounds such as BP and dibenzothiophene (DBT) in dual substrate degradation were observed. Strain PH-08 exhibited the evidence of meta-cleavage pathway as confirmed by the activity and gene expression of catechol-2,3-dioxygenase. Newly isolated bacterial strain, Agrobacterium sp. PH-08, grew well with and degraded DF via both angular and lateral dioxygenation as demonstrated by metabolites identified through ESI LC-MS/MS and GC-MS analyses. The other heterocyclic pollutants were also cometabolically degraded. Few reports have described the complete degradation of DF by a cometabolic lateral pathway. Our study demonstrates the novel results that the newly isolated strain utilized the DF as a sole carbon source and mineralized it via multiple dioxygenation. © 2013 The Society for Applied Microbiology.

  13. Newly graduated nurses use of knowledge sources in clinical decison-making - a qualitative study

    DEFF Research Database (Denmark)

    Voldbjerg, Siri

    of clinical decisions, based on transparent, articulate and reflective use of knowledge sources. Furthermore, it is implied that nurses are able to retrieve, asses, implement and evaluate research evidence. To meet these requirements, nursing educations around the world have organised curricula to educate...... graduated nurses do not work within a framework of evidence-based practice. The overall aim of this thesis was to explore which knowledge sources newly graduated nurses’ use in their clinical decision-making and why they use them in order to understand why newly graduated nurses use research and components...... within evidence-based practice to a limited extent. The thesis is based on a synthesis of findings from two studies. The aim of the first study was to explore which knowledge sources newly graduated nurses use in clinical decision making as reported within international qualitative research. The purpose...

  14. Characterization of newly isolated lytic bacteriophages active against Acinetobacter baumannii.

    Directory of Open Access Journals (Sweden)

    Maia Merabishvili

    Full Text Available Based on genotyping and host range, two newly isolated lytic bacteriophages, myovirus vB_AbaM_Acibel004 and podovirus vB_AbaP_Acibel007, active against Acinetobacter baumannii clinical strains, were selected from a new phage library for further characterization. The complete genomes of the two phages were analyzed. Both phages are characterized by broad host range and essential features of potential therapeutic phages, such as short latent period (27 and 21 min, respectively, high burst size (125 and 145, respectively, stability of activity in liquid culture and low frequency of occurrence of phage-resistant mutant bacterial cells. Genomic analysis showed that while Acibel004 represents a novel bacteriophage with resemblance to some unclassified Pseudomonas aeruginosa phages, Acibel007 belongs to the well-characterized genus of the Phikmvlikevirus. The newly isolated phages can serve as potential candidates for phage cocktails to control A. baumannii infections.

  15. Developing Automatic Water Table Control System for Reducing Greenhouse Gas Emissions from Paddy Fields

    Science.gov (United States)

    Arif, C.; Fauzan, M. I.; Satyanto, K. S.; Budi, I. S.; Masaru, M.

    2018-05-01

    Water table in rice fields play important role to mitigate greenhouse gas (GHG) emissions from paddy fields. Continuous flooding by maintenance water table 2-5 cm above soil surface is not effective and release more GHG emissions. System of Rice Intensification (SRI) as alternative rice farming apply intermittent irrigation by maintaining lower water table is proven can reduce GHG emissions reducing productivity significantly. The objectives of this study were to develop automatic water table control system for SRI application and then evaluate the performances. The control system was developed based on fuzzy logic algorithms using the mini PC of Raspberry Pi. Based on laboratory and field tests, the developed system was working well as indicated by lower MAPE (mean absolute percentage error) values. MAPE values for simulation and field tests were 16.88% and 15.80%, respectively. This system can save irrigation water up to 42.54% without reducing productivity significantly when compared to manual irrigation systems.

  16. Detection of Quinoline in G. boninense-Infected Plants Using Functionalized Multi-Walled Carbon Nanotubes: A Field Study.

    Science.gov (United States)

    Akanbi, Fowotade Sulayman; Yusof, Nor Azah; Abdullah, Jaafar; Sulaiman, Yusran; Hushiarian, Roozbeh

    2017-07-01

    Carbon nanotubes (CNTs) reinforced with gold nanoparticles (AuNPs) and chitosan nanoparticles (CTSNPs) were anchored on a screen-printed electrode to fabricate a multi-walled structure for the detection of quinoline. The surface morphology of the nanocomposites and the modified electrode was examined by an ultra-high resolution field emission scanning electron microscope (FESEM), and Fourier-transform infrared (FT-IR) spectroscopy was used to confirm the presence of specific functional groups on the multi-walled carbon nanotubes MWCNTs. Cyclic voltammetry (CV) and linear sweep voltammetry (LSV) were used to monitor the layer-by-layer assembly of ultra-thin films of nanocomposites on the surface of the electrode and other electrochemical characterizations. Under optimized conditions, the novel sensor displayed outstanding electrochemical reactivity towards the electro-oxidation of quinoline. The linear range was fixed between 0.0004 and 1.0 μM, with a limit of detection (LOD) of 3.75 nM. The fabricated electrode exhibited high stability with excellent sensitivity and selectivity, specifically attributable to the salient characteristics of AuNPs, CTSNPs, and MWCNTs and the synergistic inter-relationship between them. The newly developed electrode was tested in the field. The Ipa increased with an increase in the amount of quinoline solution added, and the peak potential deviated minimally, depicting the real capability of the newly fabricated electrode.

  17. Detection of Quinoline in G. boninense-Infected Plants Using Functionalized Multi-Walled Carbon Nanotubes: A Field Study

    Directory of Open Access Journals (Sweden)

    Fowotade Sulayman Akanbi

    2017-07-01

    Full Text Available Carbon nanotubes (CNTs reinforced with gold nanoparticles (AuNPs and chitosan nanoparticles (CTSNPs were anchored on a screen-printed electrode to fabricate a multi-walled structure for the detection of quinoline. The surface morphology of the nanocomposites and the modified electrode was examined by an ultra-high resolution field emission scanning electron microscope (FESEM, and Fourier-transform infrared (FT-IR spectroscopy was used to confirm the presence of specific functional groups on the multi-walled carbon nanotubes MWCNTs. Cyclic voltammetry (CV and linear sweep voltammetry (LSV were used to monitor the layer-by-layer assembly of ultra-thin films of nanocomposites on the surface of the electrode and other electrochemical characterizations. Under optimized conditions, the novel sensor displayed outstanding electrochemical reactivity towards the electro-oxidation of quinoline. The linear range was fixed between 0.0004 and 1.0 μM, with a limit of detection (LOD of 3.75 nM. The fabricated electrode exhibited high stability with excellent sensitivity and selectivity, specifically attributable to the salient characteristics of AuNPs, CTSNPs, and MWCNTs and the synergistic inter-relationship between them. The newly developed electrode was tested in the field. The Ipa increased with an increase in the amount of quinoline solution added, and the peak potential deviated minimally, depicting the real capability of the newly fabricated electrode.

  18. Coping Profiles Differentiate Psychological Adjustment in Chinese Women Newly Diagnosed With Breast Cancer.

    Science.gov (United States)

    Li, Lingyan; Li, Shichen; Wang, Yuping; Yi, Jinyao; Yang, Yanjie; He, Jincai; Zhu, Xiongzhao

    2017-06-01

    The study aimed to explore latent profiles of coping in Chinese women newly diagnosed with breast cancer and examine the differences of psychological distress, demographic, and medical characteristics across profiles. Latent profile analysis was used to identify 3 classes of copers based on data from 618 Chinese women newly diagnosed with breast cancer who completed questionnaires assessing their coping strategies and psychological distress. "Adaptive coper," reporting most use of adaptive cognitive coping strategies, behaviors of acceptance and shifting attention, and least use of maladaptive cognitive coping strategies, had the best psychological adjustment. "Negative coper," characterized by most use of maladaptive cognitive coping strategies, least use of adaptive cognitive coping strategies except "putting in perspective," and median levels of medical coping behaviors, had the worst psychological adjustment. "Inconsistent coper," with great use of all cognitive coping strategies, and most behaviors of fighting against the disease, and fewest behaviors of attention shift, had relatively high levels of psychological distress. Younger age, less education, shorter time since diagnosis, widowed, living in rural areas, and undergoing chemotherapy are possible markers for patients with less adaptive coping patterns. Interventions should be developed according to the different coping profiles of patients, and the key group to target is "negative copers," who may benefit from cognitive behavioral approaches that combine emotion, cognition and behavior, which could help them more effectively appraise and cope with stressful events.

  19. Theory Development and Convergence of Human Resource Fields: Implications for Human Performance Technology

    Science.gov (United States)

    Cho, Yonjoo; Yoon, Seung Won

    2010-01-01

    This study examines major theory developments in human resource (HR) fields and discusses implications for human performance technology (HPT). Differentiated HR fields are converging to improve organizational performance through knowledge-based innovations. Ruona and Gibson (2004) made a similar observation and analyzed the historical evolution…

  20. Prognostic factors of nasopharynx tumors investigated by MR imaging and the value of MR imaging in the newly published TNM staging

    International Nuclear Information System (INIS)

    Sakata, Koh-ichi; Hareyama, Masato; Tamakawa, Mituharu; Oouchi, Atushi; Sido, Mitsuo; Nagakura, Hisayasu; Akiba, Hidenari; Koito, Kazumitsu; Himi, Tetsuo; Asakura, Kohji

    1999-01-01

    Purpose: To examine the usefulness of MR imaging for predicting local control of nasopharyngeal carcinoma (NPC) and the value of MR imaging in the newly published fifth edition of the TNM classification. Methods and Materials: We studied 29 patients with NPC with MR imaging and CT before and after treatment. Staging was done according to the fourth and newly published fifth editions of the International Union Against Cancer (UICC) staging system. The radiotherapy protocol was designed to deliver 66 to 68 Gy to the primary tumor and clinically involved nodes. Results: MR proved better than CT at identifying obliteration of the pharyngobasilar fascia, invasion of the sinus of Morgagni, through which the cartilaginous portion of the eustachian tube and the levator veli palatini muscle pass, invasion of the skull base, and metastases to lymph nodes in the carotid and retropharyngeal spaces. All seven patients without invasion of the pharyngobasilar fascia had local control. The local control rates of patients with invasion of the skull base were not good (60 to 73%). There was no apparent relationship between tumor volume determined by T1-weighted MR images and local control when the tumor volume was more than 20 cc. The newly published N staging system appears to successfully identify the high-risk group for distant metastasis as N3. In our series, four of five patients with N3 disease developed distant metastases. Conclusion: Deep infiltration of the tumor is a more important prognostic factor in NPC than tumor volume. Since the newly published T staging system requires a search for tumor invasion into soft tissue such as parapharyngeal space and bony structures, MR imaging may be indispensable for the newly published NPC staging system