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Sample records for networks undergoing simultaneous

  1. Constitutive models for rubber networks undergoing simultaneous crosslinking and scission.

    Energy Technology Data Exchange (ETDEWEB)

    Thompson, Aidan Patrick; Curro, John G.; Rottach, Dana R. (University of New Mexico, Albuquerque, NM); Grest, Gary Stephen; Budzien, Joanne L.; Lo, David Chi S.

    2006-01-01

    Constitutive models for chemically reacting networks are formulated based on a generalization of the independent network hypothesis. These models account for the coupling between chemical reaction and strain histories, and have been tested by comparison with microscopic molecular dynamics simulations. An essential feature of these models is the introduction of stress transfer functions that describe the interdependence between crosslinks formed and broken at various strains. Efforts are underway to implement these constitutive models into the finite element code Adagio. Preliminary results are shown that illustrate the effects of changing crosslinking and scission rates and history.

  2. Simultaneous Fleet Deployment and Network Design of Liner Shipping

    DEFF Research Database (Denmark)

    Gelareh, Shahin; Pisinger, David

    A mixed integer linear programming formulation is proposed for the simultaneous design of network and fleet deployment of a liner service providers for deep-sea shipping. The underlying network design problem is based on a 4-index (5-index by considering capacity type) formulation of the hub...

  3. Water Pipeline Network Analysis Using Simultaneous Loop Flow ...

    African Journals Online (AJOL)

    2013-03-01

    Mar 1, 2013 ... solving for the unknown in water network analysis. It is based on a loop iterative computation. Newton-Raphson method is a better technique for solving the network problems; however, the method adopted here computes simultaneous flow corrections for all loops, hence, the best since the computational.

  4. Determinants of long-term outcome in patients undergoing simultaneous resection of synchronous colorectal liver metastases.

    Directory of Open Access Journals (Sweden)

    Qi Lin

    Full Text Available BACKGROUND: It remains unclear which patients can benefit from simultaneous resection of synchronous colorectal liver metastases (SCRLMs. This study aimed to examine the prognostic value of patient- and tumor-related factors in predicting long-term outcomes of patients undergoing simultaneous resection of SCRLMs and to help patients select a suitable therapeutic regimen and proper surveillance. METHODS: Clinicopathological and outcome data of 154 consecutive SCRLM patients who underwent simultaneous resection between July 2003 and July 2013 were collected from our prospectively established SCRLM data and analyzed with univariate and multivariate methods, and the prognostic index (PI was formulated based on the regression coefficients (β of the Cox model. The patients were classified into high- and low-risk groups according to the PI value; the cut-off point was the third quartile. RESULTS: The 5-year overall survival rate was 46%, and the 5-year disease-free survival rate was 35%. Five factors were found to be independent predictors of poor overall survival (OS by multivariate analysis: positive lymph node status, vascular invasion, BRAF mutation, the distribution of bilobar liver metastases (LMs and non-R0 resection of LMs. Compared to low PI (≤5.978, high PI (>5.978 was highly predictive of shorter OS. Three factors were found to be independent predictors of poor disease-free survival (DFS by multivariate analysis: tumor deposits, BRAF mutation and bilobar LM distribution. We also determined the PI for DFS. Compared to low PI (≤2.945, high PI (>2.945 was highly predictive of shorter DFS. CONCLUSIONS: Simultaneous resection of SCRLM may lead to various long-term outcomes. Patients with low PI have longer OS and DFS, while those with high PI have shorter OS and DFS. Thus, patients with high PI may receive more aggressive treatment and intensive surveillance, This model needs further validation.

  5. A nonaffine network model for elastomers undergoing finite deformations

    Science.gov (United States)

    Davidson, Jacob D.; Goulbourne, N. C.

    2013-08-01

    In this work, we construct a new physics-based model of rubber elasticity to capture the strain softening, strain hardening, and deformation-state dependent response of rubber materials undergoing finite deformations. This model is unique in its ability to capture large-stretch mechanical behavior with parameters that are connected to the polymer chemistry and can also be easily identified with the important characteristics of the macroscopic stress-stretch response. The microscopic picture consists of two components: a crosslinked network of Langevin chains and an entangled network with chains confined to a nonaffine tube. These represent, respectively, changes in entropy due to thermally averaged chain conformations and changes in entropy due to the magnitude of these conformational fluctuations. A simple analytical form for the strain energy density is obtained using Rubinstein and Panyukov's single-chain description of network behavior. The model only depends on three parameters that together define the initial modulus, extent of strain softening, and the onset of strain hardening. Fits to large stretch data for natural rubber, silicone rubber, VHB 4905 (polyacrylate rubber), and b186 rubber (a carbon black-filled rubber) are presented, and a comparison is made with other similar constitutive models of large-stretch rubber elasticity. We demonstrate that the proposed model provides a complete description of elastomers undergoing large deformations for different applied loading configurations. Moreover, since the strain energy is obtained using a clear set of physical assumptions, this model may be tested and used to interpret the results of computer simulation and experiments on polymers of known microscopic structure.

  6. Simultaneous optimization of water and heat exchange networks

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Zhiyou; Hou, Yanlong; Li, Xiaoduan; Wang, Jingtao [Tianjin University, Tianjin (China)

    2014-04-15

    This paper focuses on the simultaneous optimization of the heat-integrated water allocation networks. A mathematic model is established to illustrate the modified state-space representation of this problem. An easy logical method is employed to help identify the streams of hot or cold ones. In this model, the water exchange networks (WEN), heat exchange networks (HEN), and the interactions between the WEN and HEN combine together as one unity. Thus, the whole network can be solved at one time, which enhances the possibility to get a global optimal result. Examples from the literature and a PVC plant are analyzed to illustrate the accuracy and applicability of this method.

  7. Complex patterns of synchrony in networks undergoing exogenous drive

    Science.gov (United States)

    Waddell, Jack; Zochowski, Michal

    2007-03-01

    It has been established that various exogenous oscillatory drives modulate neural activity (and potentially information processing) in the brain. We explore the effect of an exogenous drive on the spatio-temporal pattern formation of a network of coupled non-identical R"ossler oscillators. We investigate the formation and properties of the phase locked states, dependent on the network properties as well as those of the external drive. We have found that such drive has a complex effect on the pattern formation in the network, depending on the coupling strength between the oscillators, drive strength as well as its frequency relative to the oscillators.

  8. Molecular Dynamics Simulations of Polymer Networks Undergoing Sequential Cross-Linking and Scission Reactions

    DEFF Research Database (Denmark)

    Rottach, Dana R.; Curro, John G.; Budzien, Joanne

    2007-01-01

    The effects of sequential cross-linking and scission of polymer networks formed in two states of strain are investigated using molecular dynamics simulations. Two-stage networks are studied in which a network formed in the unstrained state (stage 1) undergoes additional cross-linking in a uniaxia......The effects of sequential cross-linking and scission of polymer networks formed in two states of strain are investigated using molecular dynamics simulations. Two-stage networks are studied in which a network formed in the unstrained state (stage 1) undergoes additional cross......, a fraction (quantified by the stress transfer function ) of the second-stage cross-links contribute to the effective first-stage cross-link density. The stress transfer functions extracted from the MD simulations of the reacting networks are found to be in very...

  9. Will electrical cyber-physical interdependent networks undergo first-order transition under random attacks?

    Science.gov (United States)

    Ji, Xingpei; Wang, Bo; Liu, Dichen; Dong, Zhaoyang; Chen, Guo; Zhu, Zhenshan; Zhu, Xuedong; Wang, Xunting

    2016-10-01

    Whether the realistic electrical cyber-physical interdependent networks will undergo first-order transition under random failures still remains a question. To reflect the reality of Chinese electrical cyber-physical system, the "partial one-to-one correspondence" interdependent networks model is proposed and the connectivity vulnerabilities of three realistic electrical cyber-physical interdependent networks are analyzed. The simulation results show that due to the service demands of power system the topologies of power grid and its cyber network are highly inter-similar which can effectively avoid the first-order transition. By comparing the vulnerability curves between electrical cyber-physical interdependent networks and its single-layer network, we find that complex network theory is still useful in the vulnerability analysis of electrical cyber-physical interdependent networks.

  10. Simultaneous Visualization of Different Utility Networks for Disaster Management

    Science.gov (United States)

    Semm, S.; Becker, T.; Kolbe, T. H.

    2012-07-01

    Cartographic visualizations of crises are used to create a Common Operational Picture (COP) and enforce Situational Awareness by presenting and representing relevant information. As nearly all crises affect geospatial entities, geo-data representations have to support location-specific decision-making throughout the crises. Since, Operator's attention span and their working memory are limiting factors for the process of getting and interpreting information; the cartographic presentation has to support individuals in coordinating their activities and with handling highly dynamic situations. The Situational Awareness of operators in conjunction with a COP are key aspects of the decision making process and essential for coming to appropriate decisions. Utility networks are one of the most complex and most needed systems within a city. The visualization of utility infrastructure in crisis situations is addressed in this paper. The paper will provide a conceptual approach on how to simplify, aggregate, and visualize multiple utility networks and their components to meet the requirements of the decision-making process and to support Situational Awareness.

  11. Predicting Final GPA of Graduate School Students: Comparing Artificial Neural Networking and Simultaneous Multiple Regression

    Science.gov (United States)

    Anderson, Joan L.

    2006-01-01

    Data from graduate student applications at a large Western university were used to determine which factors were the best predictors of success in graduate school, as defined by cumulative graduate grade point average. Two statistical models were employed and compared: artificial neural networking and simultaneous multiple regression. Both models…

  12. A Class of Methods for the Analysis of Blade Tip Timing Data from Bladed Assemblies Undergoing Simultaneous Resonances—Part I: Theoretical Development

    Directory of Open Access Journals (Sweden)

    J. Gallego-Garrido

    2007-01-01

    Full Text Available Blade tip timing is a technique for the measurement of vibrations in rotating bladed assemblies. Although the fundamentals of the technique are simple, the analysis of data obtained in the presence of simultaneously occurring synchronous resonances is problematic. A class of autoregressive-based methods for the analysis of blade tip timing data from assemblies undergoing two simultaneous resonances has been developed. It includes approaches that assume both sinusoidal and general blade tip responses. The methods can handle both synchronous and asynchronous resonances. An exhaustive evaluation of the approaches was performed on simulated data in order to determine their accuracy and sensitivity. One of the techniques was found to perform best on asynchronous resonances and one on synchronous resonances. Both methods yielded very accurate vibration frequency estimates under all conditions of interest.

  13. Maintenance immunosuppression for adults undergoing liver transplantation: a network meta-analysis.

    Science.gov (United States)

    Rodríguez-Perálvarez, Manuel; Guerrero-Misas, Marta; Thorburn, Douglas; Davidson, Brian R; Tsochatzis, Emmanuel; Gurusamy, Kurinchi Selvan

    2017-03-31

    As part of liver transplantation, immunosuppression (suppressing the host immunity) is given to prevent graft rejections resulting from the immune response of the body against transplanted organ or tissues from a different person whose tissue antigens are not compatible with those of the recipient. The optimal maintenance immunosuppressive regimen after liver transplantation remains uncertain. To assess the comparative benefits and harms of different maintenance immunosuppressive regimens in adults undergoing liver transplantation through a network meta-analysis and to generate rankings of the different immunosuppressive regimens according to their safety and efficacy. We searched CENTRAL, MEDLINE, Embase, Science Citation Index Expanded, World Health Organization International Clinical Trials Registry Platform, and trials registers until October 2016 to identify randomised clinical trials on immunosuppression for liver transplantation. We included only randomised clinical trials (irrespective of language, blinding, or publication status) in adult participants undergoing liver transplantation (or liver retransplantation) for any reason. We excluded trials in which participants had undergone multivisceral transplantation or participants with established graft rejections. We considered any of the various maintenance immunosuppressive regimens compared with each other. We performed a network meta-analysis with OpenBUGS using Bayesian methods and calculated the odds ratio, rate ratio, and hazard ratio (HR) with 95% credible intervals (CrI) based on an available-case analysis, according to National Institute of Health and Care Excellence Decision Support Unit guidance. We included a total of 26 trials (3842 participants) in the review, and 23 trials (3693 participants) were included in one or more outcomes in the review. The vast majority of the participants underwent primary liver transplantation. All of the trials were at high risk of bias, and all of the evidence was

  14. The Simultaneous Effects of Spatial and Social Networks on Cholera Transmission

    Directory of Open Access Journals (Sweden)

    Sophia Giebultowicz

    2011-01-01

    Full Text Available This study uses social network and spatial analytical methods simultaneously to understand cholera transmission in rural Bangladesh. Both have been used separately to incorporate context into health studies, but using them together is a new and recent approach. Data include a spatially referenced longitudinal demographic database consisting of approximately 200,000 people and a database of all laboratory-confirmed cholera cases from 1983 to 2003. A complete kinship-based network linking households is created, and distance matrices are also constructed to model spatial relationships. A spatial error-social effects model tested for cholera clustering in socially linked households while accounting for spatial factors. Results show that there was social clustering in five out of twenty-one years while accounting for both known and unknown environmental variables. This suggests that environmental cholera transmission is significant and social networks also influence transmission, but not as consistently. Simultaneous spatial and social network analysis may improve understanding of disease transmission.

  15. A Class of Methods for the Analysis of Blade Tip Timing Data from Bladed Assemblies Undergoing Simultaneous Resonances—Part II: Experimental Validation

    Directory of Open Access Journals (Sweden)

    J. Gallego-Garrido

    2007-01-01

    Full Text Available Blade tip timing is a technique for the measurement of vibrations in rotating bladed assemblies. In Part I of this work a class of methods for the analysis of blade tip timing data from bladed assemblies undergoing two simultaneous synchronous resonances was developed. The approaches were demonstrated using data from a mathematical simulation of tip timing data. In Part II the methods are validated on an experimental test rig. First, the construction and characteristics of the rig will be discussed. Then, the performance of the analysis techniques when applied to data from the rig will be compared and analysed. It is shown that accurate frequency estimates are obtained by all the methods for both single and double resonances. Furthermore, the recovered frequencies are used to calculate the amplitudes of the blade tip responses. The presence of mistuning in the bladed assembly does not affect the performance of the new techniques.

  16. Simultaneous detection of duplex DNA oligonucleotides using a SERS-based micro-network gradient chip.

    Science.gov (United States)

    Choi, Namhyun; Lee, Kangsun; Lim, Dong Woo; Lee, Eun Kyu; Chang, Soo-Ik; Oh, Kwang W; Choo, Jaebum

    2012-12-21

    We report the development of a programmable surface-enhanced Raman scattering (SERS)-based micro-network gradient platform to simultaneously detect two different types of DNA oligomer mixtures. The utility of this platform was demonstrated by quantitative analysis of two breast cancer-related (BRCA1) DNA oligomer mixtures. To generate on-demand concentration gradients, the microfluidic circuit was designed using an electric-hydraulic analogy. Then a multi-gradient microfluidic channel was fabricated based on the theoretical design of the concentration control module. These micro-network structures automatically produce a series of different concentration gradients by continuously mixing Cy3-labeled DNA oligomers (BRAC1-Mutation) with TAMRA-labeled DNA oligomer (BRAC1-Wild). The SERS signals for different ratios of duplex DNA oligomer mixtures, adsorbed on the surface of silver nanoparticles, were measured under flowing conditions. Total analysis time from serial mixing to SERS detection takes less than 10 min because all experimental conditions are automatically controlled inside the exquisitely designed microfluidic channel. This novel SERS-based DNA sensing technology in a micro-network gradient channel is expected to be a powerful analytical tool to simultaneously detect multiple DNA oligomer mixtures.

  17. Simultaneous Wireless Power Transfer and Secure Multicasting in Cooperative Decode-and-Forward Relay Networks.

    Science.gov (United States)

    Lee, Jong-Ho; Sohn, Illsoo; Kim, Yong-Hwa

    2017-05-16

    In this paper, we investigate simultaneous wireless power transfer and secure multicasting via cooperative decode-and-forward (DF) relays in the presence of multiple energy receivers and eavesdroppers. Two scenarios are considered under a total power budget: maximizing the minimum harvested energy among the energy receivers under a multicast secrecy rate constraint; and maximizing the multicast secrecy rate under a minimum harvested energy constraint. For both scenarios, we solve the transmit power allocation and relay beamformer design problems by using semidefinite relaxation and bisection technique. We present numerical results to analyze the energy harvesting and secure multicasting performances in cooperative DF relay networks.

  18. An Energy Efficient Simultaneous-Node Repositioning Algorithm for Mobile Sensor Networks

    Directory of Open Access Journals (Sweden)

    Muhammad Amir Khan

    2014-01-01

    Full Text Available Recently, wireless sensor network (WSN applications have seen an increase in interest. In search and rescue, battlefield reconnaissance, and some other such applications, so that a survey of the area of interest can be made collectively, a set of mobile nodes is deployed. Keeping the network nodes connected is vital for WSNs to be effective. The provision of connectivity can be made at the time of startup and can be maintained by carefully coordinating the nodes when they move. However, if a node suddenly fails, the network could be partitioned to cause communication problems. Recently, several methods that use the relocation of nodes for connectivity restoration have been proposed. However, these methods have the tendency to not consider the potential coverage loss in some locations. This paper addresses the concerns of both connectivity and coverage in an integrated way so that this gap can be filled. A novel algorithm for simultaneous-node repositioning is introduced. In this approach, each neighbour of the failed node, one by one, moves in for a certain amount of time to take the place of the failed node, after which it returns to its original location in the network. The effectiveness of this algorithm has been verified by the simulation results.

  19. An energy efficient simultaneous-node repositioning algorithm for mobile sensor networks.

    Science.gov (United States)

    Khan, Muhammad Amir; Hasbullah, Halabi; Nazir, Babar; Khan, Imran Ali

    2014-01-01

    Recently, wireless sensor network (WSN) applications have seen an increase in interest. In search and rescue, battlefield reconnaissance, and some other such applications, so that a survey of the area of interest can be made collectively, a set of mobile nodes is deployed. Keeping the network nodes connected is vital for WSNs to be effective. The provision of connectivity can be made at the time of startup and can be maintained by carefully coordinating the nodes when they move. However, if a node suddenly fails, the network could be partitioned to cause communication problems. Recently, several methods that use the relocation of nodes for connectivity restoration have been proposed. However, these methods have the tendency to not consider the potential coverage loss in some locations. This paper addresses the concerns of both connectivity and coverage in an integrated way so that this gap can be filled. A novel algorithm for simultaneous-node repositioning is introduced. In this approach, each neighbour of the failed node, one by one, moves in for a certain amount of time to take the place of the failed node, after which it returns to its original location in the network. The effectiveness of this algorithm has been verified by the simulation results.

  20. Simultaneous trimodal MR-PET-EEG imaging for the investigation of resting state networks in humans

    Energy Technology Data Exchange (ETDEWEB)

    Neuner, Irene [RWTH Aachen (Germany); Institute of Neuroscience and Medicine - 4, Forschungszentrum Juelich GmbH (Germany); Mauler, Joerg; Arrubla, Jorge; Kops, Elena Rota; Tellmann, Lutz; Scheins, Jurgen; Herzog, Hans [Institute of Neuroscience and Medicine - 4, Forschungszentrum Juelich GmbH (Germany); Langen, Karl Josef; Shah, Jon [RWTH Aachen (Germany)

    2015-05-18

    Glucose is the principal source of energy for the brain and its relationship to neuronal activity are poorly understood. The human brain uses 80% of its energy for ongoing neural activity that occurs in isolation from any particular stimulus. A promising tool for the investigation of glucose metabolism and its relationship to neuronal activity is simultaneous trimodal MR-PET-EEG data imaging. We here demonstrate the first in vivo human trimodal data at 3T. In one session MR, FDG-PET and EEG data were recorded simultaneously at a 3T hybrid MR-BrainPET scanner (Siemens, Germany) equipped with a 32 channel MR-compatible EEG system (Brain Products, Germany) in 11 healthy volunteers (11 males, mean age: 25.2 years SD: 1.2). MR and EEG data acquisition MP-RAGE (TR = 2250 ms, TE= 3.03 ms, 176 sagittal slices. 1 mm, GRAPPA factor 2. MR-based attenuation correction of PET data via UTE: flip angle=15. Two different echo times TE1=0.07 and TE2=2.46 ms, TR=200 ms. EPI sequence (TR: 2.2 s, TE: 30 ms, FOV: 200 mm, 165 volumes, The subjects were requested to close their eyes and relax EEG data were recorded using a 32-channel MR compatible EEG system. App. 200 MBq/μmol FDG were injected, data were acquired in list mode and iteratively reconstructed with all necessary corrections into 153 slices with 256 x 256 voxels sized 1.25 mm{sup 3}. The trimodal approach, recording PET data, MR data and EEG data simultaneously was successful. The high neuronal activity of the structures within the default mode network occurs on the basis of a high glucose consumption rate within the default node network. The activity of the default mode is not tied to a special EEG frequency band.

  1. Broca Pars Triangularis Constitutes a "Hub" of the Language-Control Network during Simultaneous Language Translation.

    Science.gov (United States)

    Elmer, Stefan

    2016-01-01

    Until now, several branches of research have fundamentally contributed to a better understanding of the ramifications of bilingualism, multilingualism, and language expertise on psycholinguistic-, cognitive-, and neural implications. In this context, it is noteworthy to mention that from a cognitive perspective, there is a strong convergence of data pointing to an influence of multilingual speech competence on a variety of cognitive functions, including attention, short-term- and working memory, set shifting, switching, and inhibition. In addition, complementary neuroimaging findings have highlighted a specific set of cortical and subcortical brain regions which fundamentally contribute to administrate cognitive control in the multilingual brain, namely Broca's area, the middle-anterior cingulate cortex, the inferior parietal lobe, and the basal ganglia. However, a disadvantage of focusing on group analyses is that this procedure only enables an approximation of the neural networks shared within a population while at the same time smoothing inter-individual differences. In order to address both commonalities (i.e., within group analyses) and inter-individual variability (i.e., single-subject analyses) in language control mechanisms, here I measured five professional simultaneous interpreters while the participants overtly translated or repeated sentences with a simple subject-verb-object structure. Results demonstrated that pars triangularis was commonly activated across participants during backward translation (i.e., from L2 to L1), whereas the other brain regions of the "control network" showed a strong inter-individual variability during both backward and forward (i.e., from L1 to L2) translation. Thus, I propose that pars triangularis plays a crucial role within the language-control network and behaves as a fundamental processing entity supporting simultaneous language translation.

  2. USE OF NEURAL NETWORK SIMULATION TO MONITOR PATIENTS UNDERGOING RADICAL PROSTATECTOMY

    National Research Council Canada - National Science Library

    I. V. Lukyanov; N. A. Demchenko

    2014-01-01

    .... Based on neural network simulation, the Department of Urology, Russian Medical Academy of Postgraduate Education, has developed an accounting prognostic system to monitor the postoperative course...

  3. A Simultaneously Antimicrobial, Protein-Repellent, and Cell-Compatible Polyzwitterion Network.

    Science.gov (United States)

    Kurowska, Monika; Eickenscheidt, Alice; Guevara-Solarte, Diana-Lorena; Widyaya, Vania Tanda; Marx, Franziska; Al-Ahmad, Ali; Lienkamp, Karen

    2017-04-10

    A simultaneously antimicrobial, protein-repellent, and cell-compatible surface-attached polymer network is reported, which reduces the growth of bacterial biofilms on surfaces through its multifunctionality. The coating was made from a poly(oxonorbornene)-based zwitterion (PZI), which was surface-attached and cross-linked in one step by simultaneous UV-activated CH insertion and thiol-ene reaction. The process was applicable to both laboratory surfaces like silicon, glass, and gold and real-life surfaces like polyurethane foam wound dressings. The chemical structure and physical properties of the PZI surface and the two reference surfaces SMAMP ("synthetic mimic of an antimicrobial peptide"), an antimicrobial but protein-adhesive polymer coating, and PSB (poly(sulfobetaine)), a protein-repellent but not antimicrobial polyzwitterion coating were characterized by Fourier transform infrared spectroscopy, ellipsometry, contact angle measurements, photoelectron spectroscopy, swellability measurements (using surface plasmon resonance spectroscopy, SPR), zeta potential measurements, and atomic force microscopy. The time-dependent antimicrobial activity assay (time-kill assay) confirmed the high antimicrobial activity of the PZI; SPR was used to demonstrate that it was also highly protein-repellent. Biofilm formation studies showed that the material effectively reduced the growth of Escherichia coli and Staphylococcus aureus biofilms. Additionally, it was shown that the PZI was highly compatible with immortalized human mucosal gingiva keratinocytes and human red blood cells using the Alamar Blue assay, the live-dead stain, and the hemolysis assay. PZI thus may be an attractive coating for biomedical applications, particularly for the fight against bacterial biofilms on medical devices and in other applications.

  4. Simultaneous Wireless Information and Power Transfer for MIMO Interference Channel Networks Based on Interference Alignment

    Directory of Open Access Journals (Sweden)

    Anming Dong

    2017-09-01

    Full Text Available This paper considers power splitting (PS-based simultaneous wireless information and power transfer (SWIPT for multiple-input multiple-output (MIMO interference channel networks where multiple transceiver pairs share the same frequency spectrum. As the PS model is adopted, an individual receiver splits the received signal into two parts for information decoding (ID and energy harvesting (EH, respectively. Aiming to minimize the total transmit power, transmit precoders, receive filters and PS ratios are jointly designed under a predefined signal-to-interference-plus-noise ratio (SINR and EH constraints. The formulated joint transceiver design and power splitting problem is non-convex and thus difficult to solve directly. In order to effectively obtain its solution, the feasibility conditions of the formulated non-convex problem are first analyzed. Based on the analysis, an iterative algorithm is proposed by alternatively optimizing the transmitters together with the power splitting factors and the receivers based on semidefinite programming (SDP relaxation. Moreover, considering the prohibitive computational cost of the SDP for practical applications, a low-complexity suboptimal scheme is proposed by separately designing interference-suppressing transceivers based on interference alignment (IA and optimizing the transmit power allocation together with splitting factors. The transmit power allocation and receive power splitting problem is then recast as a convex optimization problem and solved efficiently. To further reduce the computational complexity, a low-complexity scheme is proposed by calculating the transmit power allocation and receive PS ratios in closed-form. Simulation results show the effectiveness of the proposed schemes in achieving SWIPT for MIMO interference channel (IC networks.

  5. Simultaneous Electroencephalography and Functional Magnetic Resonance Imaging and the Identification of Epileptic Networks in Children.

    Science.gov (United States)

    Maloney, Thomas C; Tenney, Jeffrey R; Szaflarski, Jerzy P; Vannest, Jennifer

    EEG/fMRI takes advantage of the high temporal resolution of EEG in combination with the high spatial resolution of fMRI. These features make it particularly applicable to the study of epilepsy in which the event duration (e.g., interictal epileptiform discharges) is short, typically less than 200 milliseconds. Interictal or ictal discharges can be identified on EEG and be used for source localization in fMRI analyses. The acquisition of simultaneous EEG/fMRI involves the use of specialized EEG hardware that is safe in the MR environment and comfortable to the participant. Advanced data analysis approaches such as independent component analysis conducted alone or sometimes combined with other, e.g., Granger Causality or "sliding window" analyses are currently thought to be most appropriate for EEG/fMRI data. These approaches make it possible to identify networks of brain regions associated with ictal and/or interictal events allowing examination of the mechanisms critical for generation and propagation through these networks. After initial evaluation in adults, EEG/fMRI has been applied to the examination of the pediatric epilepsy syndromes including Childhood Absence Epilepsy, Benign Epilepsy with Centrotemporal Spikes (BECTS), Dravet Syndrome, and Lennox-Gastaut Syndrome. Results of EEG/fMRI studies suggest that the hemodynamic response measured by fMRI may have a different shape in response to epileptic events compared to the response to external stimuli; this may be especially true in the developing brain. Thus, the main goal of this review is to provide an overview of the pediatric applications of EEG/fMRI and its associated findings up until this point.

  6. Active Noise Control Using a Functional Link Artificial Neural Network with the Simultaneous Perturbation Learning Rule

    Directory of Open Access Journals (Sweden)

    Ya-li Zhou

    2009-01-01

    Full Text Available In practical active noise control (ANC systems, the primary path and the secondary path may be nonlinear and time-varying. It has been reported that the linear techniques used to control such ANC systems exhibit degradation in performance. In addition, the actuators of an ANC system very often have nonminimum-phase response. A linear controller under such situations yields poor performance. A novel functional link artificial neural network (FLANN-based simultaneous perturbation stochastic approximation (SPSA algorithm, which functions as a nonlinear mode-free (MF controller, is proposed in this paper. Computer simulations have been carried out to demonstrate that the proposed algorithm outperforms the standard filtered-x least mean square (FXLMS algorithm, and performs better than the recently proposed filtered-s least mean square (FSLMS algorithm when the secondary path is time-varying. This observation implies that the SPSA-based MF controller can eliminate the need of the modeling of the secondary path for the ANC system.

  7. Quantum inspired PSO for the optimization of simultaneous recurrent neural networks as MIMO learning systems.

    Science.gov (United States)

    Luitel, Bipul; Venayagamoorthy, Ganesh Kumar

    2010-06-01

    Training a single simultaneous recurrent neural network (SRN) to learn all outputs of a multiple-input-multiple-output (MIMO) system is a difficult problem. A new training algorithm developed from combined concepts of swarm intelligence and quantum principles is presented. The training algorithm is called particle swarm optimization with quantum infusion (PSO-QI). To improve the effectiveness of learning, a two-step learning approach is introduced in the training. The objective of the learning in the first step is to find the optimal set of weights in the SRN considering all output errors. In the second step, the objective is to maximize the learning of each output dynamics by fine tuning the respective SRN output weights. To demonstrate the effectiveness of the PSO-QI training algorithm and the two-step learning approach, two examples of an SRN learning MIMO systems are presented. The first example is learning a benchmark MIMO system and the second one is the design of a wide area monitoring system for a multimachine power system. From the results, it is observed that SRNs can effectively learn MIMO systems when trained using the PSO-QI algorithm and the two-step learning approach. Copyright 2009 Elsevier Ltd. All rights reserved.

  8. Morphology and damping behavior of polyurethane/PMMA simultaneous interpenetrating networks

    Directory of Open Access Journals (Sweden)

    Wang S.H.

    2001-01-01

    Full Text Available A series of polyurethane/PMMA simultaneous interpenetrating networks (SINs with various hard segment contents (X in the polyurethane phase (X = 15.5 to 36.5% in polyurethane and wide range of polyurethane (PU to polyacrylate (PA ratio (PU/PA = 20:80 to 80:20 were prepared, and the damping and mechanical properties of these materials were studied. The damping of polyurethane soft phase was increased and shifted to lower temperature with increased content of PA vitreous phase. The mechanical properties were improved with increasing PA contents. The results show that PA and the polyurethane hard segment interaction play a special role in chain interpenetration density and its magnitude is revealed by the decreased dispersed domain size observed by scanning electron microscopy (SEM and increased loss area as measured by dynamic mechanical thermal analysis (DMTA. When the weight ratio of PU/PA was 40:60, the resulting SIN materials possessed better damping properties, independent of X concentration.

  9. Social Network, Surgeon, and Media Influence on the Decision to Undergo Contralateral Prophylactic Mastectomy.

    Science.gov (United States)

    Venetis, Maria K; MacGeorge, Erina L; Baptiste, Dadrie F; Mouton, Ashton; Friley, Lorin B; Pastor, Rebekah; Hatten, Kristen; Lagoo, Janaka; Bowling, Monet W; Clare, Susan E

    2016-07-26

    The rate of contralateral prophylactic mastectomy (CPM) has risen sharply in the past decade. The current study was designed to examine social network, surgeon, and media influence on patients' CPM decision-making, examining not only who influenced the decision, and to what extent, but also the type of influence exerted. Patients (N=113) who underwent CPM at 4 Indiana University-affiliated hospitals between 2008 and 2012 completed structured telephone interviews in 2013. Questions addressed the involvement and influence of the social network (family, friends, and nonsurgeon health professionals), surgeon, and media on the CPM decision. Spouses, children, family, friends, and health professionals were reported as exerting a meaningful degree of influence on patients' decisions, largely in ways that were positive or neutral toward CPM. Most surgeons were regarded as providing options rather than encouraging or discouraging CPM. Media influence was present, but limited. Patients who choose CPM do so with influence and support from members of their social networks. Reversing the increasing choice of CPM will require educating these influential others, which can be accomplished by encouraging patients to include them in clinical consultations, and by providing patients with educational materials that can be shared with their social networks. Surgeons need to be perceived as having an opinion, specifically that CPM should be reserved for those patients for whom it is medically indicated.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially. http://creativecommons.org/licenses/by-nc-nd/4.0/.

  10. Different-Level Simultaneous Minimization Scheme for Fault Tolerance of Redundant Manipulator Aided with Discrete-Time Recurrent Neural Network

    Directory of Open Access Journals (Sweden)

    Long Jin

    2017-09-01

    Full Text Available By incorporating the physical constraints in joint space, a different-level simultaneous minimization scheme, which takes both the robot kinematics and robot dynamics into account, is presented and investigated for fault-tolerant motion planning of redundant manipulator in this paper. The scheme is reformulated as a quadratic program (QP with equality and bound constraints, which is then solved by a discrete-time recurrent neural network. Simulative verifications based on a six-link planar redundant robot manipulator substantiate the efficacy and accuracy of the presented acceleration fault-tolerant scheme, the resultant QP and the corresponding discrete-time recurrent neural network.

  11. Different-Level Simultaneous Minimization Scheme for Fault Tolerance of Redundant Manipulator Aided with Discrete-Time Recurrent Neural Network.

    Science.gov (United States)

    Jin, Long; Liao, Bolin; Liu, Mei; Xiao, Lin; Guo, Dongsheng; Yan, Xiaogang

    2017-01-01

    By incorporating the physical constraints in joint space, a different-level simultaneous minimization scheme, which takes both the robot kinematics and robot dynamics into account, is presented and investigated for fault-tolerant motion planning of redundant manipulator in this paper. The scheme is reformulated as a quadratic program (QP) with equality and bound constraints, which is then solved by a discrete-time recurrent neural network. Simulative verifications based on a six-link planar redundant robot manipulator substantiate the efficacy and accuracy of the presented acceleration fault-tolerant scheme, the resultant QP and the corresponding discrete-time recurrent neural network.

  12. IMPLEMENTATION OF IMPROVED NETWORK LIFETIME TECHNIQUE FOR WSN USING CLUSTER HEAD ROTATION AND SIMULTANEOUS RECEPTION

    Directory of Open Access Journals (Sweden)

    Arun Vasanaperumal

    2015-11-01

    Full Text Available There are number of potential applications of Wireless Sensor Networks (WSNs like wild habitat monitoring, forest fire detection, military surveillance etc. All these applications are constrained for power from a stand along battery power source. So it becomes of paramount importance to conserve the energy utilized from this power source. A lot of efforts have gone into this area recently and it remains as one of the hot research areas. In order to improve network lifetime and reduce average power consumption, this study proposes a novel cluster head selection algorithm. Clustering is the preferred architecture when the numbers of nodes are larger because it results in considerable power savings for large networks as compared to other ones like tree or star. Since majority of the applications generally involve more than 30 nodes, clustering has gained widespread importance and is most used network architecture. The optimum number of clusters is first selected based on the number of nodes in the network. When the network is in operation the cluster heads in a cluster are rotated periodically based on the proposed cluster head selection algorithm to increase the network lifetime. Throughout the network single-hop communication methodology is assumed. This work will serve as an encouragement for further advances in the low power techniques for implementing Wireless Sensor Networks (WSNs.

  13. Simultaneous submicrometric 3D imaging of the micro-vascular network and the neuronal system in a mouse spinal cord

    CERN Document Server

    Fratini, Michela; Campi, Gaetano; Brun, Francesco; Tromba, Giuliana; Modregger, Peter; Bucci, Domenico; Battaglia, Giuseppe; Spadon, Raffaele; Mastrogiacomo, Maddalena; Requardt, Herwig; Giove, Federico; Bravin, Alberto; Cedola, Alessia

    2014-01-01

    Defaults in vascular (VN) and neuronal networks of spinal cord are responsible for serious neurodegenerative pathologies. Because of inadequate investigation tools, the lacking knowledge of the complete fine structure of VN and neuronal systems is a crucial problem. Conventional 2D imaging yields incomplete spatial coverage leading to possible data misinterpretation, whereas standard 3D computed tomography imaging achieves insufficient resolution and contrast. We show that X-ray high-resolution phase-contrast tomography allows the simultaneous visualization of three-dimensional VN and neuronal systems of mouse spinal cord at scales spanning from millimeters to hundreds of nanometers, with neither contrast agent nor a destructive sample-preparation. We image both the 3D distribution of micro-capillary network and the micrometric nerve fibers, axon-bundles and neuron soma. Our approach is a crucial tool for pre-clinical investigation of neurodegenerative pathologies and spinal-cord-injuries. In particular, it s...

  14. A comparison of cangrelor, prasugrel, ticagrelor, and clopidogrel in patients undergoing percutaneous coronary intervention: A network meta-analysis.

    Science.gov (United States)

    Westman, Peter C; Lipinski, Michael J; Torguson, Rebecca; Waksman, Ron

    2017-03-01

    Newer P2Y12 inhibitors have more rapid onset of platelet inhibition compared with clopidogrel, especially the intravenous P2Y12 inhibitor cangrelor. Direct comparisons between cangrelor and oral P2Y12 inhibitors ticagrelor and prasugrel do not exist. Thus, we performed a network meta-analysis to directly and indirectly compare different P2Y12 inhibitors in patients undergoing percutaneous coronary intervention (PCI). MEDLINE/PubMed and ClinicalTrials.gov were searched for randomized controlled trials (RCTs) that compared at least two P2Y12 inhibitors including cangrelor, clopidogrel, prasugrel, and ticagrelor. Network meta-analysis with a Bayesian approach was performed to directly and indirectly compare the effects of the aforementioned P2Y12 inhibitors on clinical outcomes. Odds ratios with credible intervals (OR [CrIs]) were generated with random-effects models to compare outcomes. This analysis included 15 RCTs with 54,025 patients randomized to cangrelor (n=12,475), clopidogrel (n=26,903), prasugrel (n=7455), or ticagrelor (n=7192) at time of PCI. Patients had a mean age of 63±10, 74% were male, and 82% underwent PCI for acute coronary syndrome. No significant differences between cangrelor and clopidogrel were found with respect to cardiovascular death (OR 1.01 [CrI 0.23-4.39]), myocardial infarction (OR 0.94 [CrI 0.69-1.25]), major adverse cardiac events (OR 0.91 [CrI 0.69-1.18]), stent thrombosis (OR 0.66 [CrI 0.37-1.19]), or major bleeding (OR 1.52 [CrI 0.79-2.98]). Rank probability data suggested that ticagrelor and prasugrel were better than cangrelor for reducing ischemic events, though these differences were not significant. Despite rapid platelet inhibition provided by cangrelor, newer oral P2Y12 inhibitors such as ticagrelor and prasugrel have comparable clinical outcomes. Copyright © 2016 Elsevier Inc. All rights reserved.

  15. Simultaneous extraction of roads and buildings in remote sensing imagery with convolutional neural networks

    Science.gov (United States)

    Alshehhi, Rasha; Marpu, Prashanth Reddy; Woon, Wei Lee; Mura, Mauro Dalla

    2017-08-01

    Extraction of man-made objects (e.g., roads and buildings) from remotely sensed imagery plays an important role in many urban applications (e.g., urban land use and land cover assessment, updating geographical databases, change detection, etc). This task is normally difficult due to complex data in the form of heterogeneous appearance with large intra-class and lower inter-class variations. In this work, we propose a single patch-based Convolutional Neural Network (CNN) architecture for extraction of roads and buildings from high-resolution remote sensing data. Low-level features of roads and buildings (e.g., asymmetry and compactness) of adjacent regions are integrated with Convolutional Neural Network (CNN) features during the post-processing stage to improve the performance. Experiments are conducted on two challenging datasets of high-resolution images to demonstrate the performance of the proposed network architecture and the results are compared with other patch-based network architectures. The results demonstrate the validity and superior performance of the proposed network architecture for extracting roads and buildings in urban areas.

  16. Unified Framework for Deriving Simultaneous Equation Algorithms for Water Distribution Networks

    Science.gov (United States)

    The known formulations for steady state hydraulics within looped water distribution networks are re-derived in terms of linear and non-linear transformations of the original set of partly linear and partly non-linear equations that express conservation of mass and energy. All of ...

  17. Characterization of computer network events through simultaneous feature selection and clustering of intrusion alerts

    Science.gov (United States)

    Chen, Siyue; Leung, Henry; Dondo, Maxwell

    2014-05-01

    As computer network security threats increase, many organizations implement multiple Network Intrusion Detection Systems (NIDS) to maximize the likelihood of intrusion detection and provide a comprehensive understanding of intrusion activities. However, NIDS trigger a massive number of alerts on a daily basis. This can be overwhelming for computer network security analysts since it is a slow and tedious process to manually analyse each alert produced. Thus, automated and intelligent clustering of alerts is important to reveal the structural correlation of events by grouping alerts with common features. As the nature of computer network attacks, and therefore alerts, is not known in advance, unsupervised alert clustering is a promising approach to achieve this goal. We propose a joint optimization technique for feature selection and clustering to aggregate similar alerts and to reduce the number of alerts that analysts have to handle individually. More precisely, each identified feature is assigned a binary value, which reflects the feature's saliency. This value is treated as a hidden variable and incorporated into a likelihood function for clustering. Since computing the optimal solution of the likelihood function directly is analytically intractable, we use the Expectation-Maximisation (EM) algorithm to iteratively update the hidden variable and use it to maximize the expected likelihood. Our empirical results, using a labelled Defense Advanced Research Projects Agency (DARPA) 2000 reference dataset, show that the proposed method gives better results than the EM clustering without feature selection in terms of the clustering accuracy.

  18. Broca Pars Triangularis Constitutes a “Hub” of the Language-Control Network during Simultaneous Language Translation

    Directory of Open Access Journals (Sweden)

    Stefan Elmer

    2016-09-01

    Full Text Available Until now, several branches of research have fundamentally contributed to a better understanding of the ramifications of bilingualism, multilingualism, and language expertise on psycholinguistic-, cognitive-, and neural implications. In this context, it is noteworthy to mention that from a cognitive perspective, there is a strong convergence of data pointing to an influence of multilingual speech competence on a variety of cognitive functions, including attention, short-term- and working memory, set shifting, switching, and inhibition. In addition, complementary neuroimaging findings have highlighted a specific set of cortical and subcortical brain regions which fundamentally contribute to administrate cognitive control in the multilingual brain, namely Broca’s area, the middle-anterior cingulate cortex, the inferior parietal lobe, and the basal ganglia. However, a disadvantage of focusing on group analyses is that this procedure only enables an approximation of the neural networks shared within a population while at the same time smoothing inter-individual differences. In order to address both commonalities (i.e., within group analyses and inter-individual variability (i.e., single-subject analyses in language control mechanisms, here I measured five professional simultaneous interpreters while the participants overtly translated or repeated sentences with a simple subject-verb-object structure. Results demonstrated that pars triangularis was commonly activated across participants during backward translation (i.e., from L2 to L1, whereas the other brain regions of the control network showed a strong inter-individual variability during both backward and forward (i.e., from L1 to L2 translation. Thus, I propose that pars triangularis plays a crucial role within the language-control network and behaves as a fundamental processing entity supporting simultaneous language translation.

  19. An interspecies regulatory network inferred from simultaneous RNA-seq of Candida albicans invading innate immune cells

    Directory of Open Access Journals (Sweden)

    Lanay eTierney

    2012-03-01

    Full Text Available The ability to adapt to diverse micro-environmental challenges encountered within a host is of pivotal importance to the opportunistic fungal pathogen C. albicans. We have quantified C.albicans and M. musculus gene expression dynamics during phagocytosis by dendritic cells in a genome-wide, time-resolved analysis using simultaneous RNA-seq. A robust network inference map was generated from this dataset using NetGenerator, predicting novel interactions between the host and the pathogen. We experimentally verified predicted interdependent sub-networkscomprising Hap3 in C. albicans, and Ptx3 and Mta2 in M. musculus. Remarkably, binding of recombinant Ptx3 to the C. albicans cell wall was found to regulate the expression of fungal Hap3 target genes as predicted by the network inference model. Pre-incubation of C. albicans with recombinant Ptx3 significantly altered the expression of Mta2 target cytokines such as IL-2 and IL-4 in a Hap3-dependent manner, further suggesting a role for Mta2 in host-pathogen interplay as predicted in the network inference model. We propose an integrated model for the functionality of these sub-networks during fungal invasion of immune cells, according to which binding of Ptx3 to the C. albicans cell wall induces remodelling via fungal Hap3 target genes, thereby altering the immune response to the pathogen. We show the applicability of network inference to predict interactions between host-pathogen pairs, demonstrating the usefulness of this systems biology approach to decipher mechanisms of microbial pathogenesis.

  20. Simultaneous Optimization of Road Tolls and Tradable Credits in Public-private Mixed Networks

    Directory of Open Access Journals (Sweden)

    Nan Jiang

    2017-12-01

    Full Text Available This paper investigates a hybrid management policy of road tolls and tradable credits in mixed road networks with both public and private roads. In the public sub-network, a tradable credit scheme is applied to mitigate traffic congestion. In the private sub-network, tolls are collected by the private company, but the toll levels and toll locations are determined by the government. The purpose of toll charge is two-fold: on the one hand, the government uses it as a tool for mitigating congestion; on the other hand, a threshold of revenue should be guaranteed for the profitability of the private company. A bi-level programming model is formulated to minimize the total travel time in the network by taking into account the user equilibrium travel behaviour and the revenue requirement of private firms. To obtain a  global optimum solution, the bi-level model is transformed into an equivalent single-level mixed integer linear program that can be easily solved with commercial software. Numerical examples are provided to demonstrate the effectiveness of the developed model and the efficiency of the proposed algorithm. It is shown that the mixed management schemes can achieve favourable targets, namely, joint implementation of road tolls and tradable credits can effectively mitigate traffic congestion and meanwhile maintain reasonable revenue for the private company.

  1. Broca Pars Triangularis Constitutes a “Hub” of the Language-Control Network during Simultaneous Language Translation

    Science.gov (United States)

    Elmer, Stefan

    2016-01-01

    Until now, several branches of research have fundamentally contributed to a better understanding of the ramifications of bilingualism, multilingualism, and language expertise on psycholinguistic-, cognitive-, and neural implications. In this context, it is noteworthy to mention that from a cognitive perspective, there is a strong convergence of data pointing to an influence of multilingual speech competence on a variety of cognitive functions, including attention, short-term- and working memory, set shifting, switching, and inhibition. In addition, complementary neuroimaging findings have highlighted a specific set of cortical and subcortical brain regions which fundamentally contribute to administrate cognitive control in the multilingual brain, namely Broca's area, the middle-anterior cingulate cortex, the inferior parietal lobe, and the basal ganglia. However, a disadvantage of focusing on group analyses is that this procedure only enables an approximation of the neural networks shared within a population while at the same time smoothing inter-individual differences. In order to address both commonalities (i.e., within group analyses) and inter-individual variability (i.e., single-subject analyses) in language control mechanisms, here I measured five professional simultaneous interpreters while the participants overtly translated or repeated sentences with a simple subject-verb-object structure. Results demonstrated that pars triangularis was commonly activated across participants during backward translation (i.e., from L2 to L1), whereas the other brain regions of the “control network” showed a strong inter-individual variability during both backward and forward (i.e., from L1 to L2) translation. Thus, I propose that pars triangularis plays a crucial role within the language-control network and behaves as a fundamental processing entity supporting simultaneous language translation. PMID:27746729

  2. Effective Connectivity of Cortical Sensorimotor Networks During Finger Movement Tasks: A Simultaneous fNIRS, fMRI, EEG Study.

    Science.gov (United States)

    Anwar, A R; Muthalib, M; Perrey, S; Galka, A; Granert, O; Wolff, S; Heute, U; Deuschl, G; Raethjen, J; Muthuraman, Muthuraman

    2016-09-01

    Recently, interest has been growing to understand the underlying dynamic directional relationship between simultaneously activated regions of the brain during motor task performance. Such directionality analysis (or effective connectivity analysis), based on non-invasive electrophysiological (electroencephalography-EEG) and hemodynamic (functional near infrared spectroscopy-fNIRS; and functional magnetic resonance imaging-fMRI) neuroimaging modalities can provide an estimate of the motor task-related information flow from one brain region to another. Since EEG, fNIRS and fMRI modalities achieve different spatial and temporal resolutions of motor-task related activation in the brain, the aim of this study was to determine the effective connectivity of cortico-cortical sensorimotor networks during finger movement tasks measured by each neuroimaging modality. Nine healthy subjects performed right hand finger movement tasks of different complexity (simple finger tapping-FT, simple finger sequence-SFS, and complex finger sequence-CFS). We focused our observations on three cortical regions of interest (ROIs), namely the contralateral sensorimotor cortex (SMC), the contralateral premotor cortex (PMC) and the contralateral dorsolateral prefrontal cortex (DLPFC). We estimated the effective connectivity between these ROIs using conditional Granger causality (GC) analysis determined from the time series signals measured by fMRI (blood oxygenation level-dependent-BOLD), fNIRS (oxygenated-O2Hb and deoxygenated-HHb hemoglobin), and EEG (scalp and source level analysis) neuroimaging modalities. The effective connectivity analysis showed significant bi-directional information flow between the SMC, PMC, and DLPFC as determined by the EEG (scalp and source), fMRI (BOLD) and fNIRS (O2Hb and HHb) modalities for all three motor tasks. However the source level EEG GC values were significantly greater than the other modalities. In addition, only the source level EEG showed a

  3. Simultaneous EEG and fMRI reveals a causally connected subcortical-cortical network during reward anticipation.

    Science.gov (United States)

    Plichta, Michael M; Wolf, Isabella; Hohmann, Sarah; Baumeister, Sarah; Boecker, Regina; Schwarz, Adam J; Zangl, Maria; Mier, Daniela; Diener, Carsten; Meyer, Patric; Holz, Nathalie; Ruf, Matthias; Gerchen, Martin F; Bernal-Casas, David; Kolev, Vasil; Yordanova, Juliana; Flor, Herta; Laucht, Manfred; Banaschewski, Tobias; Kirsch, Peter; Meyer-Lindenberg, Andreas; Brandeis, Daniel

    2013-09-04

    Electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) have been used to study the neural correlates of reward anticipation, but the interrelation of EEG and fMRI measures remains unknown. The goal of the present study was to investigate this relationship in response to a well established reward anticipation paradigm using simultaneous EEG-fMRI recording in healthy human subjects. Analysis of causal interactions between the thalamus (THAL), ventral-striatum (VS), and supplementary motor area (SMA), using both mediator analysis and dynamic causal modeling, revealed that (1) THAL fMRI blood oxygenation level-dependent (BOLD) activity is mediating intermodal correlations between the EEG contingent negative variation (CNV) signal and the fMRI BOLD signal in SMA and VS, (2) the underlying causal connectivity network consists of top-down regulation from SMA to VS and SMA to THAL along with an excitatory information flow through a THAL→VS→SMA route during reward anticipation, and (3) the EEG CNV signal is best predicted by a combination of THAL fMRI BOLD response and strength of top-down regulation from SMA to VS and SMA to THAL. Collectively, these findings represent a likely neurobiological mechanism mapping a primarily subcortical process, i.e., reward anticipation, onto a cortical signature.

  4. Simultaneous UV-Vis spectrophotometric quantification of ternary basic dye mixtures by partial least squares and artificial neural networks.

    Science.gov (United States)

    Hassaninejad-Darzi, Seyed Karim; Torkamanzadeh, Mohammad

    2016-11-01

    One of the main difficulties in quantification of dyes in industrial wastewaters is the fact that dyes are usually in complex mixtures rather than being pure. Here we report the development of two rapid and powerful methods, partial least squares (PLS-1) and artificial neural network (ANN), for spectral resolution of a highly overlapping ternary dye system in the presence of interferences. To this end, Crystal Violet (CV), Malachite Green (MG) and Methylene Blue (MB) were selected as three model dyes whose UV-Vis absorption spectra highly overlap each other. After calibration, both prediction models were validated through testing with an independent spectra-concentration dataset, in which high correlation coefficients (R 2 ) of 0.998, 0.999 and 0.999 were obtained by PLS-1 and 0.997, 0.999 and 0.999 were obtained by ANN for CV, MG and MB, respectively. Having shown a relative error of prediction of less than 3% for all the dyes tested, both PLS-1 and ANN models were found to be highly accurate in simultaneous determination of dyes in pure aqueous samples. Using net-analyte signal concept, the quantitative determination of dyes spiked in seawater samples was carried out successfully by PLS-1 with satisfactory recoveries (90-101%).

  5. Simultaneous EEG-fMRI reveals attention-dependent coupling of early face processing with a distributed cortical network.

    Science.gov (United States)

    Bayer, Mareike; Rubens, Michael T; Johnstone, Tom

    2017-12-12

    The speed of visual processing is central to our understanding of face perception. Yet the extent to which early visual processing influences later processing in distributed face processing networks, and the top-down modulation of such bottom-up effects, remains unclear. We used simultaneous EEG-fMRI to investigate cortical activity that showed unique covariation with ERP components of face processing (C1, P1, N170, P3), while manipulating sustained attention and transient cognitive conflict employing an emotional face-word Stroop task. ERP markers of visual processing within 100 ms after stimulus onset showed covariation with brain activation in precuneous, posterior cingulate gyrus, left middle temporal gyrus, left inferior frontal gyrus and frontal operculum, and a left lateral parietal-occipital cluster, illustrating the impact of early stage processing on higher-order mechanisms. Crucially, this covariation depended on sustained attentional focus and was absent for incongruent trials, suggesting flexible top-down gating of bottom-up processing. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

  6. Simultaneous non-destructive determination of two components of combined paracetamol and amantadine hydrochloride in tablets and powder by NIR spectroscopy and artificial neural networks.

    Science.gov (United States)

    Dou, Ying; Sun, Ying; Ren, Yuqiu; Ju, Ping; Ren, Yulin

    2005-03-09

    The two components (paracetamol and amantadine hydrochloride) were simultaneously determined in combined paracetamol and amantadine hydrochloride tablets and powder by using near-infrared (NIR) spectroscopy and artificial neural networks (ANNs). The ANN models of three pretreated spectra (first-derivative, second-derivative and standard normal variate (SNV), respectively) were established. The mathematical corrected models of tablets were compared with those of the powder. In the models, the concentrations of paracetamol and amantadine hydrochloride as the active components were determined simultaneously and compared with the results of their separate determination. The parameters that affected the network were studied and the concentrations of the test set samples were predicted. The degree of approximation, a new evaluation criterion of the network was employed to prove the accuracy of the predicted results.

  7. Simultaneous Treatment with Subcutaneous Injection of Golimumab and Intra-articular Injection of Triamcinolone Acetonide (K-Method in Patients with Rheumatoid Arthritis Undergoing Switching of Biologics: Retrospective Case–Control Study

    Directory of Open Access Journals (Sweden)

    Katsuaki Kanbe

    2016-01-01

    Full Text Available Background Tight control of severe rheumatoid arthritis (RA in patients with high disease activity, even when using biologics, is sometimes difficult using a treat-to-target strategy. Switching from one biologic to another is associated with lower efficacy than that in treatment-naive cases. We developed the K-method that involves simultaneous treatment with golimumab and intra-articular joint injection of triamcinolone acetonide (TA in patients undergoing switching of biologics. We performed this retrospective case–control study to investigate the efficacy of achieving an immediate treatment response using the K-method. Methods This study involved 20 patients with RA (control group, 10 patients; K-method group, 10 patients. Patients in the control group were switched to golimumab from other biologics without intra-articular injection of TA. The K-method involved injection of 1 mL of TA (40 mg/mL and 2 mL of 1% lidocaine hydrochloride into swollen or painful joints on the same day as golimumab treatment. A quick response one day after treatment was compared between the two groups according to the disease activity score 28 based on C-reactive protein (DAS28 CRP, clinical disease activity index (CDAI, simplified disease activity index (SDAI, European League Against Rheumatism (EULAR response, and remission rate. These parameters were investigated for 24 weeks. Results The K-method group showed significant improvements in DAS28 CRP, CDAI, and SDAI at one day, 12 weeks, and 24 weeks compared with the control group. The number of swollen and tender joints and the patient and doctor global visual analog scale scores were also significantly different between the two groups. The remission rates based on DAS28 CRP were 30% at one day, 50% at 12 weeks, and 60% at 24 weeks in the K-method group. The EULAR good/moderate response rates were 80% at one day, 90% at 12 weeks, and 90% at 24 weeks in the K-method group; however, these rates were only 10%, 40

  8. Simultaneous Treatment with Subcutaneous Injection of Golimumab and Intra-articular Injection of Triamcinolone Acetonide (K-Method) in Patients with Rheumatoid Arthritis Undergoing Switching of Biologics: Retrospective Case-Control Study.

    Science.gov (United States)

    Kanbe, Katsuaki; Chiba, Junji; Inoue, Yasuo; Taguchi, Masashi; Yabuki, Akiko; Deguchi, Tomohiko

    2016-01-01

    Tight control of severe rheumatoid arthritis (RA) in patients with high disease activity, even when using biologics, is sometimes difficult using a treat-to-target strategy. Switching from one biologic to another is associated with lower efficacy than that in treatment-naive cases. We developed the K-method that involves simultaneous treatment with golimumab and intra-articular joint injection of triamcinolone acetonide (TA) in patients undergoing switching of biologics. We performed this retrospective case-control study to investigate the efficacy of achieving an immediate treatment response using the K-method. This study involved 20 patients with RA (control group, 10 patients; K-method group, 10 patients). Patients in the control group were switched to golimumab from other biologics without intra-articular injection of TA. The K-method involved injection of 1 mL of TA (40 mg/mL) and 2 mL of 1% lidocaine hydrochloride into swollen or painful joints on the same day as golimumab treatment. A quick response one day after treatment was compared between the two groups according to the disease activity score 28 based on C-reactive protein (DAS28 CRP), clinical disease activity index (CDAI), simplified disease activity index (SDAI), European League Against Rheumatism (EULAR) response, and remission rate. These parameters were investigated for 24 weeks. The K-method group showed significant improvements in DAS28 CRP, CDAI, and SDAI at one day, 12 weeks, and 24 weeks compared with the control group. The number of swollen and tender joints and the patient and doctor global visual analog scale scores were also significantly different between the two groups. The remission rates based on DAS28 CRP were 30% at one day, 50% at 12 weeks, and 60% at 24 weeks in the K-method group. The EULAR good/moderate response rates were 80% at one day, 90% at 12 weeks, and 90% at 24 weeks in the K-method group; however, these rates were only 10%, 40%, and 40%, respectively, in the control

  9. A method for joint routing, wavelength dimensioning and fault tolerance for any set of simultaneous failures on dynamic WDM optical networks

    Science.gov (United States)

    Jara, Nicolás; Vallejos, Reinaldo; Rubino, Gerardo

    2017-11-01

    The design of optical networks decomposes into different tasks, where the engineers must basically organize the way the main system's resources are used, minimizing the design and operation costs and respecting critical performance constraints. More specifically, network operators face the challenge of solving routing and wavelength dimensioning problems while aiming to simultaneously minimize the network cost and to ensure that the network performance meets the level established in the Service Level Agreement (SLA). We call this the Routing and Wavelength Dimensioning (R&WD) problem. Another important problem to be solved is how to deal with failures of links when the network is operating. When at least one link fails, a high rate of data loss may occur. To avoid it, the network must be designed in such a manner that upon one or multiple failures, the affected connections can still communicate using alternative routes, a mechanism known as Fault Tolerance (FT). When the mechanism allows to deal with an arbitrary number of faults, we speak about Multiple Fault Tolerance (MFT). The different tasks before mentioned are usually solved separately, or in some cases by pairs, leading to solutions that are not necessarily close to optimal ones. This paper proposes a novel method to simultaneously solve all of them, that is, the Routing, the Wavelength Dimensioning, and the Multiple Fault Tolerance problems. The method allows to obtain: a) all the primary routes by which each connection normally transmits its information, b) the additional routes, called secondary routes, used to keep each user connected in cases where one or more simultaneous failures occur, and c) the number of wavelengths available at each link of the network, calculated such that the blocking probability of each connection is lower than a pre-determined threshold (which is a network design parameter), despite the occurrence of simultaneous link failures. The solution obtained by the new algorithm is

  10. A comparison of proximal and distal Chevron osteotomy, both with lateral soft-tissue release, for moderate to severe hallux valgus in patients undergoing simultaneous bilateral correction: a prospective randomised controlled trial.

    Science.gov (United States)

    Lee, K B; Cho, N Y; Park, H W; Seon, J K; Lee, S H

    2015-02-01

    Moderate to severe hallux valgus is conventionally treated by proximal metatarsal osteotomy. Several recent studies have shown that the indications for distal metatarsal osteotomy with a distal soft-tissue procedure could be extended to include moderate to severe hallux valgus. The purpose of this prospective randomised controlled trial was to compare the outcome of proximal and distal Chevron osteotomy in patients undergoing simultaneous bilateral correction of moderate to severe hallux valgus. The original study cohort consisted of 50 female patients (100 feet). Of these, four (8 feet) were excluded for lack of adequate follow-up, leaving 46 female patients (92 feet) in the study. The mean age of the patients was 53.8 years (30.1 to 62.1) and the mean duration of follow-up 40.2 months (24.1 to 80.5). After randomisation, patients underwent a proximal Chevron osteotomy on one foot and a distal Chevron osteotomy on the other. At follow-up, the American Orthopedic Foot and Ankle Society (AOFAS) hallux metatarsophalangeal interphalangeal (MTP-IP) score, patient satisfaction, post-operative complications, hallux valgus angle, first-second intermetatarsal angle, and tibial sesamoid position were similar in each group. Both procedures gave similar good clinical and radiological outcomes. This study suggests that distal Chevron osteotomy with a distal soft-tissue procedure is as effective and reliable a means of correcting moderate to severe hallux valgus as proximal Chevron osteotomy with a distal soft-tissue procedure. ©2015 The British Editorial Society of Bone & Joint Surgery.

  11. State dependent properties of epileptic brain networks: comparative graph-theoretical analyses of simultaneously recorded EEG and MEG.

    Science.gov (United States)

    Horstmann, Marie-Therese; Bialonski, Stephan; Noennig, Nina; Mai, Heinke; Prusseit, Jens; Wellmer, Jörg; Hinrichs, Hermann; Lehnertz, Klaus

    2010-02-01

    To investigate whether functional brain networks of epilepsy patients treated with antiepileptic medication differ from networks of healthy controls even during the seizure-free interval. We applied different rules to construct binary and weighted networks from EEG and MEG data recorded under a resting-state eyes-open and eyes-closed condition from 21 epilepsy patients and 23 healthy controls. The average shortest path length and the clustering coefficient served as global statistical network characteristics. Independent on the behavioral condition, epileptic brains exhibited a more regular functional network structure. Similarly, the eyes-closed condition was characterized by a more regular functional network structure in both groups. The amount of network reorganization due to behavioral state changes was similar in both groups. Consistent findings could be achieved for networks derived from EEG but hardly from MEG recordings, and network construction rules had a rather strong impact on our findings. Despite the locality of the investigated processes epileptic brain networks differ in their global characteristics from non-epileptic brain networks. Further methodological developments are necessary to improve the characterization of disturbed and normal functional networks. An increased regularity and a diminished modulation capability appear characteristic of epileptic brain networks. Copyright (c) 2009 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  12. DWI and complex brain network analysis predicts vascular cognitive impairment in spontaneous hypertensive rats undergoing executive function tests

    Directory of Open Access Journals (Sweden)

    Xavier eLópez-Gil

    2014-07-01

    Full Text Available The identification of biomarkers of vascular cognitive impairment is urgent for its early diagnosis. The aim of this study was to detect and monitor changes in brain structure and connectivity, and to correlate them with the decline in executive function. We examined the feasibility of early diagnostic magnetic resonance imaging to predict cognitive impairment before onset in an animal model of chronic hypertension: Spontaneously Hypertensive Rats. Cognitive performance was tested in an operant conditioning paradigm that evaluated learning, memory and behavioral flexibility skills. Behavioral tests were coupled with longitudinal diffusion weighted imaging acquired with 126 diffusion gradient directions and 0.3 mm3 isometric resolution at 10, 14, 18, 22, 26 and 40 weeks after birth. Diffusion weighted imaging was analyzed in 2 different ways, by regional characterization of diffusion tensor imaging indices, and by assessing changes in structural brain network organization based on Q-Ball tractography. Already at the first evaluated times, diffusion tensor imaging scalar maps revealed significant differences in many regions, suggesting loss of integrity in white and grey matter of spontaneously hypertensive rats when compared to normotensive control rats. In addition, graph theory analysis of the structural brain network demonstrated a significant decrease of hierarchical modularity, global and local efficacy, with predictive value as shown by regional 3-fold cross validation study. Moreover, these decreases were significantly correlated with the behavioral performance deficits observed at subsequent time points, suggesting that the diffusion weighted imaging and connectivity studies can unravel neuroimaging alterations even overt signs of cognitive impairment become apparent.

  13. Simultaneous characterization of elemental segregation and cementite networks in high carbon steel products by spatially-resolved laser-induced breakdown spectroscopy

    Science.gov (United States)

    Boué-Bigne, Fabienne

    2014-06-01

    The reliable characterization of the level of elemental segregation and of the extent of grain-boundary cementite networks in high carbon steel products is a prerequisite for checking product quality, for the purpose of product release to customers, and to investigate the presence of defects that may have led to mechanical property failure of the product. Current methods for the characterization of segregation and cementite networks rely on two different methods of sample etching followed by visual observation, where quality scores are given based on human perception and judgment. With the continuous demand on increasing quality, some of the conventional characterization methods and their associated scoring boards have lost relevance for the precision of characterization that is required today to distinguish between a product that will perform well and one that will not. In order to move away from a qualitative, human perception based situation for the scoring of the severity of segregation and cementite networks, a new method of data evaluation based on spatially-resolved LIBS measurements was developed to provide quantitative and simultaneous characterization of both types of defects. The quantitative assessment of segregation and cementite networks is based on the acquisition of carbon concentration maps. The ability to produce rapid scanning measurements of micro and macro-scale features with adequate spatial resolution makes LIBS the measurement method of preference for this purpose. The characterization of both different defects is extracted simultaneously and from the same carbon concentration map following a series of statistical treatment and data extraction rules. LIBS results were validated against recognized methods and were applied to a significant number of routine samples. The new LIBS method offers a step change improvement in reliability for the characterization of segregation and cementite networks in steel products over the conventional methods

  14. Program NetMoment; Simultaneous Calculation of Moment, Source Corner Frequency, and Site Specific t* from Network Recordings

    Energy Technology Data Exchange (ETDEWEB)

    Hutchings, L

    2001-12-12

    The purpose of computer program NetMoment (Appendix I) is to utilize fundamental knowledge of earthquake sources, propagation attenuation, and site response in a simultaneous inversion of network data to determine the moment and source corner frequency of earthquakes, and site specific t*. The source parameters are especially difficult to determine for small earthquakes. A fundamental problem in determining the source corner frequencies of small earthquakes is that site response can result in spectral corner frequencies in the range that may be expected from the earthquakes themselves. Several authors have identified this as fmax (Hanks, 1982), a constant corner frequency for small events so that below threshold moment (about 1.0 x 10{sup 21} dyne-cm) the corner frequency remains constant the size of events diminishes. Hutchings and Wu (1990) found that for the southern California region, events with moment less than about 1.5 x 10{sup 21} dyne-cm (about magnitude 3.4) show no source effect in their spectra. Hanks (1982) found the threshold to be about 1.0 x l0{sup 21} dyne-cm for other southern California sites. Baise et al. (2002) found borehole recordings on Yerba Buena Island, in San Francisco Bay, to have corner frequencies limited to about 3-5 Hz for M < 4.0 earthquakes in the region. Some authors have attributed this to a minimum source dimension for earthquakes, which results in a decrease in stress drop for smaller events (Archuleta et al., 1982; Papageorgiou and Aki, 1983). alternative explanation is that the constant corner frequencies result from whole path or near site attenuation and/or amplifications due to soil response. This is supported by a wide body of literature (Anderson and Hough, 1984, Hutchings and Wu, 1990, Blakeslee and Malin, 1991; Aster and Shearer, 1991; Abercrombie, 1995). Abercrombie, for example, estimated source corner frequencies from events recorded in granite at a depth of 2.5 Km in the Cajon Pass scientific drill hole and

  15. Correlated alpha activity with the facial expression processing network in a simultaneous EEG-fMRI experiment.

    Science.gov (United States)

    Simoes, Marco; Direito, Bruno; Lima, Joao; Castelhano, Joao; Ferreira, Carlos; Couceiro, Ricardo; Carvalho, Paulo; Castelo-Branco, Miguel

    2017-07-01

    The relationship between EEG and fMRI data is poorly covered in the literature. Extensive work has been conducted in resting-state and epileptic activity, highlighting a negative correlation between the alpha power band of the EEG and the BOLD activity in the default-mode-network. The identification of an appropriate task-specific relationship between fMRI and EEG data for predefined regions-of-interest, would allow the transfer of interventional paradigms (such as BOLD-based neurofeedback sessions) from fMRI to EEG, enhancing its application range by lowering its costs and improving its flexibility. In this study, we present an analysis of the correlation between task-specific alpha band fluctuations and BOLD activity in the facial expressions processing network. We characterized the network ROIs through a stringent localizer and identified two clusters on the scalp (one frontal, one parietal-occipital) with marked alpha fluctuations, related to the task. We then check whether such power variations throughout the time correlate with the BOLD activity in the network. Our results show statistically significant negative correlations between the alpha power in both clusters and for all the ROIs of the network. The correlation levels have still not met the requirements for transferring the protocol to an EEG setup, but they pave the way towards a better understand on how frontal and parietal-occipital alpha relates to the activity of the facial expressions processing network.

  16. Prevention of contrast-induced acute kidney injury in patients undergoing cardiovascular procedures-a systematic review and network meta-analysis.

    Directory of Open Access Journals (Sweden)

    Eliano P Navarese

    Full Text Available Interventional diagnostic and therapeutic procedures requiring intravascular iodinated contrast steadily increase patient exposure to the risks of contrast-induced acute kidney injury (CIAKI, which is associated with death, nonfatal cardiovascular events, and prolonged hospitalization. The aim of this study was to investigate the efficacy of pharmacological and non-pharmacological treatments for CIAKI prevention in patients undergoing cardiovascular invasive procedures with iodinated contrast.MEDLINE, Google Scholar, EMBASE and Cochrane databases as well as abstracts and presentations from major cardiovascular and nephrology meetings were searched, up to 22 April 2016. Eligible studies were randomized trials comparing strategies to prevent CIAKI (alone or in combination when added to saline versus each other, saline, placebo, or no treatment in patients undergoing cardiovascular invasive procedures with administration of iodinated contrast. Two reviewers independently extracted trial-level data including number of patients, duration of follow-up, and outcomes. Eighteen strategies aimed at CIAKI prevention were identified. The primary outcome was the occurrence of CIAKI. Secondary outcomes were mortality, myocardial infarction, dialysis and heart failure. The data were pooled using network meta-analysis. Treatment estimates were calculated as odds ratios (ORs with 95% credible intervals (CrI. 147 RCTs involving 33,463 patients were eligible. Saline plus N-acetylcysteine (OR 0.72, 95%CrI 0.57-0.88, ascorbic acid (0.59, 0.34-0.95, sodium bicarbonate plus N-acetylcysteine (0.59, 0.36-0.89, probucol (0.42, 0.15-0.91, methylxanthines (0.39, 0.20-0.66, statin (0.36, 0.21-0.59, device-guided matched hydration (0.35, 0.12-0.79, prostaglandins (0.26, 0.08-0.62 and trimetazidine (0.26, 0.09-0.59 were associated with lower odds of CIAKI compared to saline. Methylxanthines (0.12, 0.01-0.94 or left ventricular end-diastolic pressure-guided hydration (0.09, 0

  17. Prevention of contrast-induced acute kidney injury in patients undergoing cardiovascular procedures-a systematic review and network meta-analysis.

    Science.gov (United States)

    Navarese, Eliano P; Gurbel, Paul A; Andreotti, Felicita; Kołodziejczak, Michalina Marta; Palmer, Suetonia C; Dias, Sofia; Buffon, Antonino; Kubica, Jacek; Kowalewski, Mariusz; Jadczyk, Tomasz; Laskiewicz, Michał; Jędrzejek, Marek; Brockmeyer, Maximillian; Airoldi, Flavio; Ruospo, Marinella; De Servi, Stefano; Wojakowski, Wojciech; O' Connor, Christopher; Strippoli, Giovanni F M

    2017-01-01

    Interventional diagnostic and therapeutic procedures requiring intravascular iodinated contrast steadily increase patient exposure to the risks of contrast-induced acute kidney injury (CIAKI), which is associated with death, nonfatal cardiovascular events, and prolonged hospitalization. The aim of this study was to investigate the efficacy of pharmacological and non-pharmacological treatments for CIAKI prevention in patients undergoing cardiovascular invasive procedures with iodinated contrast. MEDLINE, Google Scholar, EMBASE and Cochrane databases as well as abstracts and presentations from major cardiovascular and nephrology meetings were searched, up to 22 April 2016. Eligible studies were randomized trials comparing strategies to prevent CIAKI (alone or in combination) when added to saline versus each other, saline, placebo, or no treatment in patients undergoing cardiovascular invasive procedures with administration of iodinated contrast. Two reviewers independently extracted trial-level data including number of patients, duration of follow-up, and outcomes. Eighteen strategies aimed at CIAKI prevention were identified. The primary outcome was the occurrence of CIAKI. Secondary outcomes were mortality, myocardial infarction, dialysis and heart failure. The data were pooled using network meta-analysis. Treatment estimates were calculated as odds ratios (ORs) with 95% credible intervals (CrI). 147 RCTs involving 33,463 patients were eligible. Saline plus N-acetylcysteine (OR 0.72, 95%CrI 0.57-0.88), ascorbic acid (0.59, 0.34-0.95), sodium bicarbonate plus N-acetylcysteine (0.59, 0.36-0.89), probucol (0.42, 0.15-0.91), methylxanthines (0.39, 0.20-0.66), statin (0.36, 0.21-0.59), device-guided matched hydration (0.35, 0.12-0.79), prostaglandins (0.26, 0.08-0.62) and trimetazidine (0.26, 0.09-0.59) were associated with lower odds of CIAKI compared to saline. Methylxanthines (0.12, 0.01-0.94) or left ventricular end-diastolic pressure-guided hydration (0.09, 0

  18. Net analyte signal-based simultaneous determination of antazoline and naphazoline using wavelength region selection by experimental design-neural networks.

    Science.gov (United States)

    Hemmateenejad, Bahram; Ghavami, Raoof; Miri, Ramin; Shamsipur, Majtaba

    2006-02-15

    Net analyte signal (NAS)-based multivariate calibration methods were employed for simultaneous determination of anthazoline and naphazoline. The NAS vectors calculated from the absorbance data of the drugs mixture were used as input for classical least squares (CLS), principal component and partial least squares regression PCR and PLS methods. A wavelength selection strategy was used to find the best wavelength region for each drug separately. As a new procedure, we proposed an experimental design-neural network strategy for wavelength region optimization. By use of a full factorial design method, some different wavelength regions were selected by taking into account different spectral parameters including the starting wavelength, the ending wavelength and the wavelength interval. The performance of all the multivariate calibration methods, in all selected wavelength regions for both drugs, was evaluated by calculating a fitness function based on the root mean square error of calibration and validation. A three-layered feed-forward artificial neural network (ANN) model with back-propagation learning algorithm was employed to model the nonlinear relationship between the spectral parameters and fitness of each regression method. From the resulted ANN models, the spectral regions in which lowest fitness could be obtained were chosen. Comparison of the results revealed that the net NAS-PLS resulted in lower prediction error than the other models. The proposed NAS-based calibration method was successfully applied to the simultaneous analyses of anthazoline and naphazoline in a commercial eye drop sample.

  19. Reducing handover latency in future IP-based wireless networks: Proxy Mobile IPv6 with simultaneous bindings

    NARCIS (Netherlands)

    Bargh, Mortaza S.; Hulsebosch, Bob; Eertink, Henk; Eertink, E.H.; Heijenk, Geert; Idserda, Jeroen; Laganier, Julien; Prasad, Anand R.; Zugenmaier, Alf

    2008-01-01

    Handover in future wireless communication systems must be seamless. Current IP-level mobility protocols have difficulties meeting the stringent handover delay requirements. At the same time they do not give sufficient control to the network to optimize the handover process and they do not deal well

  20. Central and peripheral chemoreceptors evoke distinct responses in simultaneously recorded neurons of the raphé-pontomedullary respiratory network

    OpenAIRE

    Nuding, Sarah C.; Segers, Lauren S.; Shannon, Roger; O'Connor, Russell; Morris, Kendall F.; Lindsey, Bruce G.

    2009-01-01

    The brainstem network for generating and modulating the respiratory motor pattern includes neurons of the medullary ventrolateral respiratory column (VRC), dorsolateral pons (PRG) and raphé nuclei. Midline raphé neurons are proposed to be elements of a distributed brainstem system of central chemoreceptors, as well as modulators of central chemoreceptors at other sites, including the retrotrapezoid nucleus. Stimulation of the raphé system or peripheral chemoreceptors can induce a long-term fa...

  1. Generalized Cartographic and Simultaneous Representation of Utility Networks for Decision-Support Systems and Crisis Management in Urban Environments

    Science.gov (United States)

    Becker, T.; König, G.

    2015-10-01

    Cartographic visualizations of crises are used to create a Common Operational Picture (COP) and enforce Situational Awareness by presenting relevant information to the involved actors. As nearly all crises affect geospatial entities, geo-data representations have to support location-specific analysis throughout the decision-making process. Meaningful cartographic presentation is needed for coordinating the activities of crisis manager in a highly dynamic situation, since operators' attention span and their spatial memories are limiting factors during the perception and interpretation process. Situational Awareness of operators in conjunction with a COP are key aspects in decision-making process and essential for making well thought-out and appropriate decisions. Considering utility networks as one of the most complex and particularly frequent required systems in urban environment, meaningful cartographic presentation of multiple utility networks with respect to disaster management do not exist. Therefore, an optimized visualization of utility infrastructure for emergency response procedures is proposed. The article will describe a conceptual approach on how to simplify, aggregate, and visualize multiple utility networks and their components to meet the requirements of the decision-making process and to support Situational Awareness.

  2. Central and peripheral chemoreceptors evoke distinct responses in simultaneously recorded neurons of the raphé-pontomedullary respiratory network.

    Science.gov (United States)

    Nuding, Sarah C; Segers, Lauren S; Shannon, Roger; O'Connor, Russell; Morris, Kendall F; Lindsey, Bruce G

    2009-09-12

    The brainstem network for generating and modulating the respiratory motor pattern includes neurons of the medullary ventrolateral respiratory column (VRC), dorsolateral pons (PRG) and raphé nuclei. Midline raphé neurons are proposed to be elements of a distributed brainstem system of central chemoreceptors, as well as modulators of central chemoreceptors at other sites, including the retrotrapezoid nucleus. Stimulation of the raphé system or peripheral chemoreceptors can induce a long-term facilitation of phrenic nerve activity; central chemoreceptor stimulation does not. The network mechanisms through which each class of chemoreceptor differentially influences breathing are poorly understood. Microelectrode arrays were used to monitor sets of spike trains from 114 PRG, 198 VRC and 166 midline neurons in six decerebrate vagotomized cats; 356 were recorded during sequential stimulation of both receptor classes via brief CO(2)-saturated saline injections in vertebral (central) and carotid arteries (peripheral). Seventy neurons responded to both stimuli. More neurons were responsive only to peripheral challenges than those responsive only to central chemoreceptor stimulation (PRG, 20 : 4; VRC, 41 : 10; midline, 25 : 13). Of 16 474 pairs of neurons evaluated for short-time scale correlations, similar percentages of reference neurons in each brain region had correlation features indicative of a specific interaction with at least one target neuron: PRG (59.6%), VRC (51.0%) and raphé nuclei (45.8%). The results suggest a brainstem network architecture with connectivity that shapes the respiratory motor pattern via overlapping circuits that modulate central and peripheral chemoreceptor-mediated influences on breathing.

  3. Simultaneous Generations of Independent Millimeter Wave and 10 Gbit/s Wired Signal by Single Electrode Modulator in TDM-PON Network

    Science.gov (United States)

    Niazi, Shahab Ahmad; Zhang, Xiaoguang; Xi, Lixia; Idress, Muhammad

    2013-03-01

    We propose and present a cost effective and simple technique of simultaneous generation and propagation of millimeter wave with recently standardized 10 giga bit passive optical network (GPON) by mixing of 2.5 Gbit/s, 30 GHz radio wave with 10 Gbit/s based band signal and then modulated by single Mach Zehnder modulator (MZM). In this scheme, we have applied 1490 nm for downstream, 1310 nm for upstream transmission and ON OFF keying (OOK) modulation format to make it fully align with existing standards and infrastructure. Simulation results show error free transmission performance with negligible power penalty over 25 km bidirectional fiber. We also highlight the principles and discuss the main technical challenges for commercial realization of 60 GHz spectrum.

  4. Complete or Culprit-Only Revascularization for Patients With Multivessel Coronary Artery Disease Undergoing Percutaneous Coronary Intervention: A Pairwise and Network Meta-Analysis of Randomized Trials.

    Science.gov (United States)

    Elgendy, Islam Y; Mahmoud, Ahmed N; Kumbhani, Dharam J; Bhatt, Deepak L; Bavry, Anthony A

    2017-02-27

    The authors sought to compare the effectiveness of the different revascularization strategies in ST-segment elevation myocardial infarction (STEMI) patients with multivessel coronary artery disease undergoing primary percutaneous coronary intervention (PCI). Recent randomized trials have suggested that multivessel complete revascularization at the time of primary percutaneous coronary intervention (PCI) is associated with better outcomes, however; the optimum timing for nonculprit PCI is unknown. Trials that randomized STEMI patients with multivessel disease to any combination of the 4 different revascularization strategies (i.e., complete revascularization at the index procedure, staged procedure during the hospitalization, staged procedure after discharge or culprit-only revascularization) were included. Random effect risk ratios (RRs) were conducted. Network meta-analysis was constructed using mixed treatment comparison models, and the 4 revascularization strategies were compared. A total of 10 trials with 2,285 patients were included. In the pairwise meta-analysis, complete revascularization (i.e., at the index procedure or as a staged procedure) was associated with a lower risk of major adverse cardiac events (MACE) (RR: 0.57; 95% confidence interval [CI]: 0.42 to 0.77), due to lower risk of urgent revascularization (RR: 0.44; 95% CI: 0.30 to 0.66). The risk of all-cause mortality (RR: 0.76; 95% CI: 0.52 to 1.12), and spontaneous reinfarction (RR: 0.54; 95% CI: 0.23 to 1.27) was similar. The reduction in the risk of MACE was observed irrespective of the timing of nonculprit artery revascularization in the mixed treatment model. Current evidence from randomized trials suggests that the risk of all-cause mortality and spontaneous reinfarction is not different among the various revascularization strategies for multivessel disease. Complete revascularization at the index procedure or as a staged procedure (either during the hospitalization or after discharge

  5. Application of smart spectrophotometric methods and artificial neural network for the simultaneous quantitation of olmesartan medoxamil, amlodipine besylate and hydrochlorothiazide in their combined pharmaceutical dosage form

    Science.gov (United States)

    2013-01-01

    Background New, simple and specific spectrophotometric methods and artificial neural network (ANN) were developed and validated in accordance with ICH guidelines for the simultaneous estimation of Olmesartan (OLM), Amlodipine (AML), and Hydrochlorothiazide (HCT) in commercial tablets. Results For spectrophotometric methods: First, Amlodipine (AML) was determined by direct spectrophotometry at 359 nm and by application of the ratio subtraction, the AML spectrum was removed from the mixture spectra. Then Hydrochlorothiazide (HCT) was determined directly at 315 nm without interference from Olmesartan medoxamil (OLM) which could be determined using the isoabsorptive method. The calibration curve is linear over the concentration range of 5–40, 2.5-40 and 2–40 μg mL-1 for AML, OLM and HCT, respectively. ANN (as a multivariate calibration method) was also applied for the simultaneous determination of the three analytes in their combined pharmaceutical dosage form using spectral region from 230–340 nm. Conclusions The proposed methods were successfully applied for the assay of the three analytes in laboratory prepared mixtures and combined pharmaceutical tablets with excellent recoveries. No interference was observed from common pharmaceutical additives. The results were favorably compared with those obtained by a reference spectrophotometric method. The methods are validated according to the ICH guidelines and accuracy, precision and repeatability are found to be within the acceptable limit. PMID:23374392

  6. Neural Network Based Active Disturbance Rejection Control of a Novel Electrohydraulic Servo System for Simultaneously Balancing and Positioning by Isoactuation Configuration

    Directory of Open Access Journals (Sweden)

    Qiang Gao

    2016-01-01

    Full Text Available To satisfy the lightweight requirements of large pipe weapons, a novel electrohydraulic servo (EHS system where the hydraulic cylinder possesses three cavities is developed and investigated in the present study. In the EHS system, the balancing cavity of the EHS is especially designed for active compensation for the unbalancing force of the system, whereas the two driving cavities are employed for positioning and disturbance rejection of the large pipe. Aiming at simultaneously balancing and positioning of the EHS system, a novel neural network based active disturbance rejection control (NNADRC strategy is developed. In the NNADRC, the radial basis function (RBF neural network is employed for online updating of parameters of the extended state observer (ESO. Thereby, the nonlinear behavior and external disturbance of the system can be accurately estimated and compensated in real time. The efficiency and superiority of the system are critically investigated by conducting numerical simulations, showing that much higher steady accuracy as well as system robustness is achieved when comparing with conventional ADRC control system. It indicates that the NNADRC is a very promising technique for achieving fast, stable, smooth, and accurate control of the novel EHS system.

  7. Artificial neural networks allow the use of simultaneous measurements of Alzheimer Disease markers for early detection of the disease

    Directory of Open Access Journals (Sweden)

    Gardoni Fabrizio

    2005-07-01

    Full Text Available Abstract Background Previous studies have shown that in platelets of mild Alzheimer Disease (AD patients there are alterations of specific APP forms, paralleled by alteration in expression level of both ADAM 10 and BACE when compared to control subjects. Due to the poor linear relation among each key-element of beta-amyloid cascade and the target diagnosis, the use of systems able to afford non linear tasks, like artificial neural networks (ANNs, should allow a better discriminating capacity in comparison with classical statistics. Objective To evaluate the accuracy of ANNs in AD diagnosis. Methods 37 mild-AD patients and 25 control subjects were enrolled, and APP, ADM10 and BACE measures were performed. Fifteen different models of feed-forward and complex-recurrent ANNs (provided by Semeion Research Centre, based on different learning laws (back propagation, sine-net, bi-modal were compared with the linear discriminant analysis (LDA. Results The best ANN model correctly identified mild AD patients in the 94% of cases and the control subjects in the 92%. The corresponding diagnostic performance obtained with LDA was 90% and 73%. Conclusion This preliminary study suggests that the processing of biochemical tests related to beta-amyloid cascade with ANNs allows a very good discrimination of AD in early stages, higher than that obtainable with classical statistics methods.

  8. Infrared variation reduction by simultaneous background suppression and target contrast enhancement for deep convolutional neural network-based automatic target recognition

    Science.gov (United States)

    Kim, Sungho

    2017-06-01

    Automatic target recognition (ATR) is a traditionally challenging problem in military applications because of the wide range of infrared (IR) image variations and the limited number of training images. IR variations are caused by various three-dimensional target poses, noncooperative weather conditions (fog and rain), and difficult target acquisition environments. Recently, deep convolutional neural network-based approaches for RGB images (RGB-CNN) showed breakthrough performance in computer vision problems, such as object detection and classification. The direct use of RGB-CNN to the IR ATR problem fails to work because of the IR database problems (limited database size and IR image variations). An IR variation-reduced deep CNN (IVR-CNN) to cope with the problems is presented. The problem of limited IR database size is solved by a commercial thermal simulator (OKTAL-SE). The second problem of IR variations is mitigated by the proposed shifted ramp function-based intensity transformation. This can suppress the background and enhance the target contrast simultaneously. The experimental results on the synthesized IR images generated by the thermal simulator (OKTAL-SE) validated the feasibility of IVR-CNN for military ATR applications.

  9. Simultaneous 10 Gbps data and polarization-based pulse-per-second clock transmission using a single VCSEL for high-speed optical fibre access networks

    Science.gov (United States)

    Isoe, G. M.; Wassin, S.; Gamatham, R. R. G.; Leitch, A. W. R.; Gibbon, T. B.

    2017-01-01

    Access networks based on vertical cavity surface emitting laser (VCSEL) transmitters offer alternative solution in delivering different high bandwidth, cost effective services to the customer premises. Clock and reference frequency distribution is critical for applications such as Coordinated Universal Time (UTC), GPS, banking and big data science projects. Simultaneous distribution of both data and timing signals over shared infrastructure is thus desirable. In this paper, we propose and experimentally demonstrate a novel, cost-effective technique for multi-signal modulation on a single VCSEL transmitter. Two signal types, an intensity modulated 10 Gbps data signal and a polarization-based pulse per second (PPS) clock signal are directly modulated onto a single VCSEL carrier at 1310 nm. Spectral efficiency is maximized by exploiting inherent orthogonal polarization switching of the VCSEL with changing bias in transmission of the PPS signal. A 10 Gbps VCSEL transmission with PPS over 11 km of G.652 fibre introduced a transmission penalty of 0.52 dB. The contribution of PPS to this penalty was found to be 0.08 dB.

  10. Outcome predictors in autism spectrum disorders preschoolers undergoing treatment as usual: insights from an observational study using artificial neural networks

    Directory of Open Access Journals (Sweden)

    Narzisi A

    2015-06-01

    Full Text Available Antonio Narzisi,1 Filippo Muratori,1,2 Massimo Buscema,3,4 Sara Calderoni,1 Enzo Grossi3,5 1Department of Developmental Neuroscience, IRCCS Stella Maris Foundation, 2Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy; 3Semeion Research Centre of Sciences of Communication, Rome, Italy; 4Department of Mathematical and Statistical Sciences, University of Colorado Denver, Denver, CO, USA; 5Autism Research Unit, Villa Santa Maria Institute, Tavernerio, Italy Background: Treatment as usual (TAU for autism spectrum disorders (ASDs includes eclectic treatments usually available in the community and school inclusion with an individual support teacher. Artificial neural networks (ANNs have never been used to study the effects of treatment in ASDs. The Auto Contractive Map (Auto-CM is a kind of ANN able to discover trends and associations among variables creating a semantic connectivity map. The matrix of connections, visualized through a minimum spanning tree filter, takes into account nonlinear associations among variables and captures connection schemes among clusters. Our aim is to use Auto-CM to recognize variables to discriminate between responders versus no responders at TAU.Methods: A total of 56 preschoolers with ASDs were recruited at different sites in Italy. They were evaluated at T0 and after 6 months of treatment (T1. The children were referred to community providers for usual treatments. Results: At T1, the severity of autism measured through the Autism Diagnostic Observation Schedule decreased in 62% of involved children (Response, whereas it was the same or worse in 37% of the children (No Response. The application of the Semeion ANNs overcomes the 85% of global accuracy (Sine Net almost reaching 90%. Consequently, some of the tested algorithms were able to find a good correlation between some variables and TAU outcome. The semantic connectivity map obtained with the application of the Auto-CM system showed

  11. On the origin of Gaussian network theory in the thermo/chemo-responsive shape memory effect of amorphous polymers undergoing photo-elastic transition

    Science.gov (United States)

    Lu, Haibao; Huang, Wei Min; Leng, Jinsong

    2016-06-01

    Amorphous polymers are normally isotropic in their physical properties, however, upon stress their structural randomness is disturbed and they become anisotropic. There is a close connection between the optical anisotropy and the elastic (or mechanical) anisotropy, since both are related to the type of symmetry exhibited by the molecular structure. On the origin of Gaussian network theory, a phenomenological constitutive framework was proposed to study the photo-elastic transition and working mechanism of the thermo-/chemo-responsive shape-memory effect (SME) in amorphous shape memory polymers (SMPs). Optically refractive index was initially employed to couple the stress, strain and the anisotropy of the random link in macromolecule chain. Based on the Arrhenius law, a constitutive framework was then applied for the temperature dependence of optical (or elastic or mechanical) anisotropy according to the fictive temperature parameter. Finally, the phenomenological photo-elastic model was proposed to quantitatively identify the influential factors behind the thermo-/chemo-responsive SME in SMPs, of which the shape recovery behavior is predicted and verified by the available experimental data reported in the literature.

  12. Relationship between early administration of abciximab and TIMI flow in STEMI patients undergoing primary angioplasty: findings from a large regional STEMI network.

    Science.gov (United States)

    Izzo, Antonio; Rosiello, Renato; Lucchini, Giuseppe; Tomasi, Luca; Mantovani, Paola; Lettieri, Corrado; Baccaglioni, Nicola; Romano, Michele; Buffoli, Francesca; Izzo, Beatrice; Zanini, Roberto

    2017-06-01

    The aim of this study is to assess whether in S-T Elevation Myocardial Infarction (STEMI) a relationship between early administration of abciximab and Thrombolysis In Myocardial Infarction (TIMI) flow before and after primary percutaneous coronary intervention (PCI) in 960 consecutive patients exists. From 1 February 2001 onward, in the Province of Mantua it has been operating a 'Cardiology Network for the Acute Infarction Care' having its Hub in the Central Coronary ICU/Cath Lab of Mantua Hospital and being its Spokes centers represented by the emergency rooms and Central Coronary ICUs of the four territorial hospitals. T1 (time from symptoms onset to first medical contact) and T2 (time from first medical contact to angioplasty) are shorter for patients rescued by first aid units rather than for those presented in emergency rooms as well as Ta (time from symptoms onset to abciximab administration). Furthermore, the patients that received abciximab before hospital arrival had less frequently a coronary occlusion [odds ratio = 0.74, 95% confidence interval (0.57-0.96), P = 0.013]. The patients with T1 less than 4 h are 753/960 (78.4%). For this type of patients, there was a significant Ta difference between the pre-PCI TIMI-flow classes (F = 4.467, df = 3, P = 0.04). Planned contrasts revealed that mean time of TIMI flow 0 (M = 104.2) is statistically different from mean time of TIMI flow 3 (M = 85.7), P = 0.013. Our results suggest that the use of abciximab, free from pharmacokinetic limits of oral P2Y12 inhibitors, should be considered in STEMI patients with early presentation before primary PCI.

  13. Simultaneous stability and sensitivity in model cortical networks is achieved through anti-correlations between the in- and out-degree of connectivity

    Directory of Open Access Journals (Sweden)

    Juan Carlos Vasquez

    2013-11-01

    Full Text Available Neuronal networks in rodent barrel cortex are characterized by stable low baseline firing rates. However, they are sensitive to the action potentials of single neurons as suggested by recent single-cell stimulation experiments that report quantifiable behavioral responses in response to short spike trains elicited in single neurons. Hence, these networks are stable against internally generated fluctuations in firing rate but at the same time remain sensitive to similarly-sized externally induced perturbations. We investigated stability and sensitivity in a simple recurrent network of stochastic binary neurons and determined numerically the effects of correlation between the number of afferent (‘in-degree’ and efferent (‘out-degree’ connections in neurons. The key advance reported in this work is that anti-correlation between in-/out-degree distributions increased the stability of the network in comparison to networks with no correlation or positive correlations, while being able to achieve the same level of sensitivity. The experimental characterization of degree distributions is difficult because all presynaptic and postsynaptic neurons have to be identified and counted. We explored whether the statistics of network motifs, which requires the characterization of connections between small subsets of neurons, could be used to detect evidence for degree anti-correlations. We find that the sample frequency of the 3-neuron ‘ring’ motif (1→2→3→1, can be used to detect degree anti-correlation for sub-networks of size 30 using about 50 samples, which is of significance because the necessary measurements are achievable experimentally in the near future.Taken together, we hypothesize that barrel cortex networks exhibit degree anti-correlations and specific network motif statistics.

  14. Long-term effectiveness of early administration of glycoprotein IIb/IIIa agents to real-world patients undergoing primary percutaneous interventions: results of a registry study in an ST-elevation myocardial infarction network.

    Science.gov (United States)

    Ortolani, Paolo; Marzocchi, Antonio; Marrozzini, Cinzia; Palmerini, Tullio; Saia, Francesco; Taglieri, Nevio; Baldazzi, Federica; Dall'Ara, Gianni; Nardini, Paola; Gianstefani, Silvia; Guastaroba, Paolo; Grilli, Roberto; Branzi, Angelo

    2009-01-01

    To evaluate the clinical impact of early administration of glycoprotein IIb/IIIa agents (IIb/IIIa agents) in the context of a dedicated hub and spoke network allowing very prompt pharmacological/mechanical interventions. Using a prospective database, we conducted a cohort study of ST-elevation myocardial infarction (STEMI) patients (n = 1124) undergoing primary percutaneous coronary interventions (PPCIs) and IIb/IIIa agents administration (period, 2003-2006). Comparisons were planned between patients receiving early IIb/IIIa agents administration (in hub/spoke centre emergency departments or during ambulance transfer; early group, n = 380) or delayed administration (in the catheterization laboratory; late group, n = 744). The primary outcome measure was long-term overall mortality/re-infarction. Baseline characteristics of the two groups were largely comparable. Angiographically, early group patients more often achieved pre-PPCI TIMI Grade 2-3 and TIMI Grade 3 flow. Clinically, the early administration group experienced lower 2-year risk of unadjusted mortality/re-infarction (17 vs. 23%; P = 0.01). After adjustment for potential confounders, early administration was associated with favourable outcome in the overall population (HR = 0.71, P = 0.03) and in high-risk subgroups (TIMI risk index >25, HR = 0.64, P = 0.02; Killip class >1, HR = 0.54, P = 0.01). In patients treated by PPCI within a STEMI network setting, early administration of IIb/IIIa agents may provide long-term clinical benefits. Notably, these results appeared magnified in high-risk patients.

  15. Brain rhythms alterations and their effect in functional networks: A simultaneous EEG/fMRI study in Fixation-off epilepsy

    OpenAIRE

    Solana Sánchez, Ana Beatriz; Hernández Tamames, J.A.; Molina, Elena; Martínez, Kenia; Alcalá, Juan José; Toledano, Rafael; San Antonio-Arce, Victoria; Garcia Morales, Irene; Gil Nagel, Antonio; Maestu Unturbe, Ceferino; Alvarez Linera, Juan; Alfayate, E.; Pozo Guerrero, Francisco del

    2012-01-01

    Fixation-off sensitivity (FOS) denotes the forms of EEG abnormalities, which are elicited by elimination of central vision or fixation. The phenomenon seems to depend on variables that modulate the alpha rhythm, however, the cerebral mechanisms underlying FOS remain unclear [1]. The scarce previous fMRI findings related to FOS have shown activation in extrastriate cortex [2] and also in frontal areas [3][4]. On the other hand, simultaneous EEG-fMRI technique has been used to assess the relati...

  16. Highly efficient simultaneous ultrasonic assisted adsorption of brilliant green and eosin B onto ZnS nanoparticles loaded activated carbon: Artificial neural network modeling and central composite design optimization

    Science.gov (United States)

    Jamshidi, M.; Ghaedi, M.; Dashtian, K.; Ghaedi, A. M.; Hajati, S.; Goudarzi, A.; Alipanahpour, E.

    2016-01-01

    In this work, central composite design (CCD) combined with response surface methodology (RSM) and desirability function approach (DFA) gives useful information about operational condition and also to obtain useful information about interaction and main effect of variables concerned to simultaneous ultrasound-assisted removal of brilliant green (BG) and eosin B (EB) by zinc sulfide nanoparticles loaded on activated carbon (ZnS-NPs-AC). Spectra overlap between BG and EB dyes was extensively reduced and/or omitted by derivative spectrophotometric method, while multi-layer artificial neural network (ML-ANN) model learned with Levenberg-Marquardt (LM) algorithm was used for building up a predictive model and prediction of the BG and EB removal. The ANN efficiently was able to forecast the simultaneous BG and EB removal that was confirmed by reasonable numerical value i.e. MSE of 0.0021 and R2 of 0.9589 and MSE of 0.0022 and R2 of 0.9455 for testing data set, respectively. The results reveal acceptable agreement among experimental data and ANN predicted results. Langmuir as the best model for fitting experimental data relevant to BG and EB removal indicates high, economic and profitable adsorption capacity (258.7 and 222.2 mg g- 1) that supports and confirms its applicability for wastewater treatment.

  17. Simultaneous influence of gas mixture composition and process temperature on Fe2O3->FeO reduction kinetics: neural network modeling

    Directory of Open Access Journals (Sweden)

    K. Piotrowski

    2005-09-01

    Full Text Available The kinetics of Fe2O3->FeO reaction was investigated. The thermogravimetric (TGA data covered the reduction of hematite both by pure species (nitrogen diluted CO or H2 and by their mixture. The conventional analysis has indicated that initially the reduction of hematite is a complex, surface controlled process, however once a thin layer of lower oxidation state iron oxides (magnetite, wüstite is formed on the surface, it changes to diffusion control. Artificial Neural Network (ANN has proved to be a convenient tool for modeling of this complex, heterogeneous reaction runs within the both (kinetic and diffusion regions, correctly considering influence of temperature and gas composition effects and their complex interactions. ANN's model shows the capability to mimic some extreme (minimum of the reaction rate within the determined temperature window, while the Arrhenius dependency is of limited use.

  18. Preventive Strategies for Contrast-Induced Acute Kidney Injury in Patients Undergoing Percutaneous Coronary Procedures: Evidence From a Hierarchical Bayesian Network Meta-Analysis of 124 Trials and 28 240 Patients.

    Science.gov (United States)

    Giacoppo, Daniele; Gargiulo, Giuseppe; Buccheri, Sergio; Aruta, Patrizia; Byrne, Robert A; Cassese, Salvatore; Dangas, George; Kastrati, Adnan; Mehran, Roxana; Tamburino, Corrado; Capodanno, Davide

    2017-05-01

    The effectiveness of currently available effective preventive strategies for contrast-induced acute kidney injury (CIAKI) is a matter of debate. We performed a Bayesian random-effects network meta-analysis of 124 trials (28 240 patients) comparing a total of 10 strategies: saline, statin, N-acetylcysteine (NAC), sodium bicarbonate (NaHCO3), NAC+NaHCO3, ascorbic acid, xanthine, dopaminergic agent, peripheral ischemic preconditioning, and natriuretic peptide. Compared with saline, the risk of CIAKI was reduced by using statin (odds ratio [OR], 0.42; 95% credible interval [CrI], 0.26-0.67), xanthine (OR, 0.32; 95% CrI, 0.17-0.57), ischemic preconditioning (OR, 0.48; 95% CrI, 0.26-0.87), NAC+NaHCO3 (OR, 0.50; 95% CrI, 0.33-0.76), NAC (OR, 0.68; 95% CrI, 0.55-0.84), and NaHCO3 (OR, 0.66; 95% CrI, 0.47-0.90). The benefit of statin therapy was consistent across multiple sensitivity analyses, whereas the efficacy of all the other strategies was questioned by restricting the analysis to high-quality trials. Overall, high heterogeneity was observed for comparisons involving xanthine and ischemic preconditioning, although the impact of NAC and xanthine was probably influenced by publication bias/small-study effect. Hydration alone was the least effective preventive strategy for CIAKI. Meta-regressions did not reveal significant associations with baseline creatinine and contrast volume. In patients with diabetes mellitus, no strategy was found to reduce the incidence of CIAKI. In patients undergoing percutaneous coronary procedures, statin administration is associated with a marked and consistent reduction in the risk of CIAKI compared with saline. Although xanthine, NAC, NaHCO3, NAC+NaHCO3, ischemic preconditioning, and natriuretic peptide may have nephroprotective effects, these results were not consistent across multiple sensitivity analyses. © 2017 American Heart Association, Inc.

  19. ASTRONAUT ALDRIN UNDERGOES SPACESUIT CHECKS

    Science.gov (United States)

    1969-01-01

    ASTRONAUT ALDRIN UNDERGOES SPACESUIT CHECKS KSC-69PC-0374 69-HC-742,S-266,ARCHIVE-00337 White undergoing spacesuit checks, Apollo 11 lunar module pilot Edwin E. Aldrin, Jr., watches Astronauts Neil A. Armstrong and Michael Collins suit up for launch.

  20. Simultaneous Cake Cutting

    DEFF Research Database (Denmark)

    Balkanski, Eric; Branzei, Simina; Kurokawa, David

    2014-01-01

    We introduce the simultaneous model for cake cutting (the fair allocation of a divisible good), in which agents simultaneously send messages containing a sketch of their preferences over the cake. We show that this model enables the computation of divisions that satisfy proportionality — a popular...

  1. Personality and Simultaneous Speech.

    Science.gov (United States)

    Feldstein, Stanley; And Others

    The purpose of the study was to examine the relationship of the limitation and outcome of simultaneous speech to those dimensions of personality indexes by Cattell's 16PF Questionnaire. More than 500 conversations of 24 female college students were computer-analyzed for instances of simultaneous speech, and the frequencies with which they…

  2. Suppression in simultaneous masking.

    Science.gov (United States)

    Fastl, H; Bechly, M

    1983-09-01

    Suppression, i.e., the decrease of masked threshold caused by the addition of a second masker M2 to a first masker M1, is measured for the case of simultaneous masking. The magnitude of suppression decreases with increasing test tone duration; pulsed maskers elicit somewhat more suppression than continuous maskers. In comparison to suppression effects obtained in nonsimultaneous masking (post-masking, pulsation threshold) suppression in simultaneous masking is considerably smaller and was found only at the lower slopes of the two maskers. Suppression in simultaneous masking would not be predicted by those models of suppression which require nonsimultaneous presentation of maskers and test sound.

  3. Metasurfaces: Simultaneous Stokes parameters

    Science.gov (United States)

    Lepetit, Thomas; Kanté, Boubacar

    2015-11-01

    Techniques for determining Stokes parameters, which fully define the polarization state of a wave, require multiple measurements, thus potentially leading to inaccuracies. Researchers now show how to simultaneously determine the parameters for visible light using periodic metal structures.

  4. Simultaneous consolidation and creep

    DEFF Research Database (Denmark)

    Krogsbøll, Anette

    1997-01-01

    Materials that exhibit creep under constant effective stress typically also show rate dependent behavior. The creep deformations and the rate sensitive behavior is very important when engineering and geological problems with large time scales are considered. When stress induced compaction (consol...... (consolidation) is retarded by slow drainage of excess pore pressure it is expected that consolidation and creep occur simultaneously. A constitutive model adressing the problems of rate sensitive behavior and simultaneous consolidation and creep is presented....

  5. Simultaneity, relativity and conventionality

    Science.gov (United States)

    Janis, Allen I.

    2008-01-01

    The view of simultaneity presented by Max Jammer is almost breathtaking, encompassing, as the book's subtitle suggests, the period from antiquity to the 21st century. Many interesting things are to be found along the way. For example, what Jammer (p. 49) says "may well be regarded as probably the earliest recorded example of an operational definition of distant simultaneity" is due to St. Augustine (in his Confessions, written in 397 A.D.; for a modern translation, see Augustine, 2006). He was arguing against astrology by presenting the story of two women, one rich and one poor, who gave birth simultaneously. Although the two children thus had precisely the same horoscopes, their lives followed quite different courses. And how was it determined that the births were simultaneous? A messenger went from each birth site to the other, leaving the instant the child was born (and, presumably, traveling with equal speeds). Since the messengers met at the midpoint between the locations of the two births, the births must have been simultaneous. This is, of course, quite analogous to Albert Einstein's definition of simultaneity (given more than 1500 years later), which will be discussed in Section 2.1.

  6. A desirability functions-based approach for simultaneous ...

    African Journals Online (AJOL)

    the industries. It is observed that only Hsieh and Tong (2001), Wu (2008) and Liao et al. (2014) have attempted to optimize quantitative and ordinal response variables simultaneously under Taguchi's framework of robust design approach. Hsieh and. Tong (2001) applied artificial neural networks for simultaneous ...

  7. Modeling the citation network by network cosmology.

    Science.gov (United States)

    Xie, Zheng; Ouyang, Zhenzheng; Zhang, Pengyuan; Yi, Dongyun; Kong, Dexing

    2015-01-01

    Citation between papers can be treated as a causal relationship. In addition, some citation networks have a number of similarities to the causal networks in network cosmology, e.g., the similar in-and out-degree distributions. Hence, it is possible to model the citation network using network cosmology. The casual network models built on homogenous spacetimes have some restrictions when describing some phenomena in citation networks, e.g., the hot papers receive more citations than other simultaneously published papers. We propose an inhomogenous causal network model to model the citation network, the connection mechanism of which well expresses some features of citation. The node growth trend and degree distributions of the generated networks also fit those of some citation networks well.

  8. Modeling the citation network by network cosmology.

    Directory of Open Access Journals (Sweden)

    Zheng Xie

    Full Text Available Citation between papers can be treated as a causal relationship. In addition, some citation networks have a number of similarities to the causal networks in network cosmology, e.g., the similar in-and out-degree distributions. Hence, it is possible to model the citation network using network cosmology. The casual network models built on homogenous spacetimes have some restrictions when describing some phenomena in citation networks, e.g., the hot papers receive more citations than other simultaneously published papers. We propose an inhomogenous causal network model to model the citation network, the connection mechanism of which well expresses some features of citation. The node growth trend and degree distributions of the generated networks also fit those of some citation networks well.

  9. Comparative Effectiveness of 12 Treatment Strategies for Preventing Contrast-Induced Acute Kidney Injury: A Systematic Review and Bayesian Network Meta-analysis

    OpenAIRE

    Su, Xiaole; Xie, Xinfang; Liu, Lijun; Lv, Jicheng; Song, Fujian; Perkovic,Vlado; Zhang, Hong

    2017-01-01

    Background: To simultaneously evaluate the relative efficacy of multiple pharmacologic strategies for preventing contrast-induced acute kidney injury (AKI). Study Design: Systematic review containing a Bayesian network meta-analysis of randomized controlled trials. Setting & Population: Participants undergoing diagnostic and/or interventional procedures with contrast media. Selection Criteria for Studies: Randomized controlled trials comparing the active drug treatments with each other or wit...

  10. Noisy Network Coding

    CERN Document Server

    Lim, Sung Hoon; Gamal, Abbas El; Chung, Sae-Young

    2010-01-01

    A noisy network coding scheme for sending multiple sources over a general noisy network is presented. For multi-source multicast networks, the scheme naturally extends both network coding over noiseless networks by Ahlswede, Cai, Li, and Yeung, and compress-forward coding for the relay channel by Cover and El Gamal to general discrete memoryless and Gaussian networks. The scheme also recovers as special cases the results on coding for wireless relay networks and deterministic networks by Avestimehr, Diggavi, and Tse, and coding for wireless erasure networks by Dana, Gowaikar, Palanki, Hassibi, and Effros. The scheme involves message repetition coding, relay signal compression, and simultaneous decoding. Unlike previous compress--forward schemes, where independent messages are sent over multiple blocks, the same message is sent multiple times using independent codebooks as in the network coding scheme for cyclic networks. Furthermore, the relays do not use Wyner--Ziv binning as in previous compress-forward sch...

  11. Simultaneous Inference in Regression

    CERN Document Server

    Liu, Wei

    2010-01-01

    The use of simultaneous confidence bands in linear regression is a vibrant area of research. This book presents an overview of the methodology and applications, including necessary background material on linear models. A special chapter on logistic regression gives readers a glimpse into how these methods can be used for generalized linear models. The appendices provide computational tools for simulating confidence bands. The author also includes MATLAB[registered] programs for all examples on the web. With many numerical examples and software implementation, this text serves the needs of rese

  12. Simultaneous immunization against tuberculosis.

    Directory of Open Access Journals (Sweden)

    Elma Z Tchilian

    Full Text Available BCG, the only licensed vaccine against tuberculosis, provides some protection against disseminated disease in infants but has little effect on prevention of adult pulmonary disease. Newer parenteral immunization prime boost regimes may provide improved protection in experimental animal models but are unproven in man so that there remains a need for new and improved immunization strategies.Mice were immunized parenterally, intranasally or simultaneously by both routes with BCG or recombinant mycobacterial antigens plus appropriate adjuvants. They were challenged with Mycobacterium tuberculosis (Mtb and the kinetics of Mtb growth in the lungs measured. We show that simultaneous immunization (SIM of mice by the intranasal and parenteral routes is highly effective in increasing protection over parenteral BCG administration alone. Intranasal immunization induces local pulmonary immunity capable of inhibiting the growth of Mtb in the early phase (the first week of infection, while parenteral immunization has a later effect on Mtb growth. Importantly, these two effects are additive and do not depend on priming and boosting the immune response. The best SIM regimes reduce lung Mtb load by up to 2 logs more than BCG given by either route alone.These data establish SIM as a novel and highly effective immunization strategy for Mtb that could be carried out at a single clinic visit. The efficacy of SIM does not depend on priming and boosting an immune response, but SIM is complementary to prime boost strategies and might be combined with them.

  13. Geodesics of simultaneity in Schwarzschild

    CERN Document Server

    Paiva, F M

    2010-01-01

    Geodesic of simultaneity is a spacelike geodesic in which every pair of neighbour events are simultaneous ($g_{0\\mu}\\dd x^\\mu=0$). These geodesics are studied in the exterior region of \\Sch's metric.

  14. Simultaneous alcohol and cannabis expectancies predict simultaneous use

    Directory of Open Access Journals (Sweden)

    Earleywine Mitch

    2006-10-01

    Full Text Available Abstract Background Simultaneous use of alcohol and cannabis predicts increased negative consequences for users beyond individual or even concurrent use of the two drugs. Given the widespread use of the drugs and common simultaneous consumption, problems unique to simultaneous use may bear important implications for many substance users. Cognitive expectancies offer a template for future drug use behavior based on previous drug experiences, accurately predicting future use and problems. Studies reveal similar mechanisms underlying both alcohol and cannabis expectancies, but little research examines simultaneous expectancies for alcohol and cannabis use. Whereas research has demonstrated unique outcomes associated with simultaneous alcohol and cannabis use, this study hypothesized that unique cognitive expectancies may underlie simultaneous alcohol and cannabis use. Results: This study examined a sample of 2600 (66% male; 34% female Internet survey respondents solicited through advertisements with online cannabis-related organizations. The study employed known measures of drug use and expectancies, as well as a new measure of simultaneous drug use expectancies. Expectancies for simultaneous use of alcohol and cannabis predicted simultaneous use over and above expectancies for each drug individually. Discussion Simultaneous expectancies may provide meaningful information not available with individual drug expectancies. These findings bear potential implications on the assessment and treatment of substance abuse problems, as well as researcher conceptualizations of drug expectancies. Policies directing the treatment of substance abuse and its funding ought to give unique consideration to simultaneous drug use and its cognitive underlying factors.

  15. Epidemics on interconnected networks

    Science.gov (United States)

    Dickison, Mark; Havlin, S.; Stanley, H. E.

    2012-06-01

    Populations are seldom completely isolated from their environment. Individuals in a particular geographic or social region may be considered a distinct network due to strong local ties but will also interact with individuals in other networks. We study the susceptible-infected-recovered process on interconnected network systems and find two distinct regimes. In strongly coupled network systems, epidemics occur simultaneously across the entire system at a critical infection strength βc, below which the disease does not spread. In contrast, in weakly coupled network systems, a mixed phase exists below βc of the coupled network system, where an epidemic occurs in one network but does not spread to the coupled network. We derive an expression for the network and disease parameters that allow this mixed phase and verify it numerically. Public health implications of communities comprising these two classes of network systems are also mentioned.

  16. Note on Magnetism and Simultaneity

    Science.gov (United States)

    Huggins, Elisha

    2009-01-01

    The paper on "Magnetism and Simultaneity" by Adler provides an excellent new thought experiment involving the lack of simultaneity in Einstein's special relativity. Adler uses the lack of simultaneity rather than the Lorentz contraction to derive the formula for the magnetic force on a moving charged particle. Advantages of his derivation are that…

  17. Simultaneous Immersion Mirau Interferometry

    Science.gov (United States)

    Lyulko, Oleksandra

    acquisition challenging. This problem was resolved by integration of polarization optics into the optics of the attachment to enable simultaneous creation and spatial separation of two interferograms, which, combined with the background image, are used to reconstruct the intensity map of the specimen. Giving the name Simultaneous Immersion Mirau Interferometry to this approach, simultaneous acquisition of all interferograms per image has eliminated the issue of vibrations. The designed compound microscope attachment has been manufactured and tested; the system produces images of quality, sufficient to perform targeted cellular irradiation experiments.

  18. Dielectric RheoSANS - Simultaneous Interrogation of Impedance, Rheology and Small Angle Neutron Scattering of Complex Fluids.

    Science.gov (United States)

    Richards, Jeffrey J; Gagnon, Cedric V L; Krzywon, Jeffery R; Wagner, Norman J; Butler, Paul D

    2017-04-10

    A procedure for the operation of a new dielectric RheoSANS instrument capable of simultaneous interrogation of the electrical, mechanical and microstructural properties of complex fluids is presented. The instrument consists of a Couette geometry contained within a modified forced convection oven mounted on a commercial rheometer. This instrument is available for use on the small angle neutron scattering (SANS) beamlines at the National Institute of Standards and Technology (NIST) Center for Neutron Research (NCNR). The Couette geometry is machined to be transparent to neutrons and provides for measurement of the electrical properties and microstructural properties of a sample confined between titanium cylinders while the sample undergoes arbitrary deformation. Synchronization of these measurements is enabled through the use of a customizable program that monitors and controls the execution of predetermined experimental protocols. Described here is a protocol to perform a flow sweep experiment where the shear rate is logarithmically stepped from a maximum value to a minimum value holding at each step for a specified period of time while frequency dependent dielectric measurements are made. Representative results are shown from a sample consisting of a gel composed of carbon black aggregates dispersed in propylene carbonate. As the gel undergoes steady shear, the carbon black network is mechanically deformed, which causes an initial decrease in conductivity associated with the breaking of bonds comprising the carbon black network. However, at higher shear rates, the conductivity recovers associated with the onset of shear thickening. Overall, these results demonstrate the utility of the simultaneous measurement of the rheo-electro-microstructural properties of these suspensions using the dielectric RheoSANS geometry.

  19. The social network of alcohol users undergoing treatment in a mental health service Red social de adictos al alcohol bajo tratamiento en un servicio de salud mental Rede social de usuários de álcool, sob tratamento, em um serviço de saúde mental

    Directory of Open Access Journals (Sweden)

    Jacqueline de Souza

    2011-02-01

    Full Text Available The treatment of alcohol and drug users requires an extended reflection on the influence of the family and other social network groups of these individuals. Thus, this study, results of a qualitative study, aimed at investigating the presence of drug users in the social network of individuals undergoing treatment and the possible interventions of the mental health services in the social network of four users of alcohol in the municipality of Alegrete/RS. Interviews with users and families, genograms and eco-maps were used. The results indicated the presence of drug users in the family and in the other social network groups, and that the group for chemical dependants was the main intervention in these social networks. These results demonstrate the need for directing the actions of mental health to develop healthy bonds, to expand the social network and structure of the group in order to provide benefits which favor effective psychosocial rehabilitation.El tratamiento de adictos al alcohol y drogas requiere una reflexión amplia sobre la influencia de la familia y otros grupos de la red social de estos individuos. Así, este estudio, resultado de una investigación cualitativa, objetivó averiguar la presencia de usuarios de drogas en la red social de individuos bajo tratamiento y las posibles intervenciones del servicio de salud mental en la red social de cuatro adictos al alcohol en el municipio de Alegrete/ RS. Fueron utilizadas entrevistas con adictos y familiares, genograma y ecomapa. Los resultados indicaron la presencia de adictos de drogas en la familia y demás grupos de las redes sociales y el grupo para dependientes químicos como principal intervención en estas redes sociales. Estos resultados evidencian la necesidad de dirigir las acciones de salud mental para el desarrollo de vínculos saludables, ampliación de la red social y estructuración del grupo de modo a proporcionar beneficios en pro de una efectiva rehabilitaci

  20. Simultaneity in Emotional Moments

    Science.gov (United States)

    Clore, Gerald L.

    Emotions are described as emergent states, which exist only to the extent that multiple affective reactions to the same object occur at the same time. Emotions are thus the confluence of thoughts, feelings, expressions, desires, and so on. They emerge as meta-cognitive representations of embodied affective reactions. Emotions may be initiated by low-level, automatic, unconscious affective reactions, which are then iteratively re-processed with ever greater cognitive involvement until they become elaborated into emotional states. Affective and emotional reactions act as information about the value of objects of judgment and of accessible cognitions and inclinations during tasks. They influence judgment and thought when they are experienced simultaneously with sensory data about the world. Affective influences thus depend on our inability to disentangle affective from descriptive perceptions. To the extent that affective reactions reflect different, incommensurate sources of value (e.g., utilitarian, moral, aesthetic), perceived persons or objects may be experienced as being transcendently good or evil. Experiments varying people's attributions for their affective experiences allow the separate roles of affective and descriptive information to be examined. However, it is the inability to parse everyday experience into its separate sources of evaluative and descriptive information that gives rise to a colourful and transcendent reality.

  1. Outcomes of liver transplantation alone after listing for simultaneous kidney: comparison to simultaneous liver kidney transplantation.

    Science.gov (United States)

    Hmoud, Bashar; Kuo, Yong-Fang; Wiesner, Russell H; Singal, Ashwani K

    2015-04-01

    Data on patient and liver graft survival comparing liver transplantation alone after listing for kidney with simultaneous liver kidney (SLK) transplantation are scanty. United Network Organ Sharing network database (1994-2011) queried for liver transplantation alone after being listed for kidney and SLK transplants. Of 65,206 first liver transplants, 3549 were listed for simultaneous kidney. Of these, 422 (12%) received only liver (LIST) and differed from SLK recipients for the white race (64% vs. 57%; 0.005), diabetes (27% vs. 37%; P = 0.02), model for end-stage liver disease era (68% vs. 82%; P = 0.0001), serum creatinine (2.9±1.9 vs. 4.3±2.5; P transplantation in LIST group (11% vs. 0.5%; P transplantation in the LIST group with 16 (4%) receiving kidney within first year after transplantation. After excluding patients receiving kidney within first year, about 33% recovered renal function to above estimated GFR of greater than 60 mL per min. Guidelines are needed for patient selection to list for and receipt of simultaneous liver kidney transplantation.

  2. Tuberculosis in children undergoing hemodialysis

    Directory of Open Access Journals (Sweden)

    Gargah Tahar

    2010-04-01

    Full Text Available Gargah Tahar1, Goucha-Louzir Rim2, Lakhoua Mohamed Rachid11Department of Pediatric Nephrology, 2Department of Nephrology, Charles Nicolle Hospital, Tunis, TunisiaAbstract: Tuberculosis (TB remains a public health problem in Tunisia. Its incidence is higher in immunocompromised hosts than in the general population. In children and during hemodialysis, TB is characterized by the frequency of extrapulmonary localizations and diagnostic difficulties. The aim of this retrospective study is to evaluate the incidence of TB in Tunisian children undergoing hemodialysis and to determine its clinical features as well as the results of chemotherapy.Method: This retrospective study includes seven TB children among 112 children on hemodialysis at the pediatric nephrology department in Charles Nicolle Hospital from 2002 to 2008. The diagnosis of TB was established by a combination of clinical, radiological, biochemical, microbiological, and histological examinations. Treatment with anti-TB drugs, the results of therapy, and the outcome of patients were noted.Results: There were four girls and three boys aged 10 to 16 years (mean, 13 years. They had been on hemodialysis for 2 to 5 years (mean, 3 years. Noted clinical features were weight loss and fever in five cases, chest pain in one case, cervical lymph node in one case, and spinal pain in one case. The organ systems involved were pleural in two cases, pulmonary in one case, peritoneal in one case, cervical lymphatic in one case, and spinal in one case. One patient was treated empirically with a good response. Diagnosis was made by isolation of mycobacterium TB in three cases, by specific histological signs observed in a lymph node biopsy in one case, in peritoneal biopsy in one case, and in discovertebral biopsy in one case. In the remaining patient, the clinical and radiological presentations were compatible with pulmonary TB. All patients received four anti-TB drugs: isoniazid, rifampicin, pyrazinamide

  3. Mixing navigation on networks

    Science.gov (United States)

    Zhou, Tao

    2008-05-01

    In this article, we propose a mixing navigation mechanism, which interpolates between random-walk and shortest-path protocol. The navigation efficiency can be remarkably enhanced via a few routers. Some advanced strategies are also designed: For non-geographical scale-free networks, the targeted strategy with a tiny fraction of routers can guarantee an efficient navigation with low and stable delivery time almost independent of network size. For geographical localized networks, the clustering strategy can simultaneously increase efficiency and reduce the communication cost. The present mixing navigation mechanism is of significance especially for information organization of wireless sensor networks and distributed autonomous robotic systems.

  4. Bulletin of International Simultaneous Observations

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The publication of the Bulletin of International Simultaneous Observations, began July 1, 1875, with daily maps added in 1877. It was published for distribution...

  5. Fulcrum Network Codes

    DEFF Research Database (Denmark)

    2015-01-01

    Fulcrum network codes, which are a network coding framework, achieve three objectives: (i) to reduce the overhead per coded packet to almost 1 bit per source packet; (ii) to operate the network using only low field size operations at intermediate nodes, dramatically reducing complexity...... in the network; and (iii) to deliver an end-to-end performance that is close to that of a high field size network coding system for high-end receivers while simultaneously catering to low-end ones that can only decode in a lower field size. Sources may encode using a high field size expansion to increase...... the number of dimensions seen by the network using a linear mapping. Receivers can tradeoff computational effort with network delay, decoding in the high field size, the low field size, or a combination thereof....

  6. Quantification of simultaneous solvent evaporation and chemical curing in thermoset coatings

    DEFF Research Database (Denmark)

    Kiil, Søren

    2010-01-01

    The mechanisms of simultaneous solvent evaporation and film formation in high-solids thermoset coatings are considered. The relevant phenomena, chemical reactions, solvent diffusion and evaporation, gelation, vitrification, network mobility restrictions, and crosslinking, are quantified and a mat...

  7. Prophylactic salpingectomy in women undergoing hysterectomy for benign gynaecological disease - a new Danish recommendation

    DEFF Research Database (Denmark)

    Sloth, Sigurd Beier; Gimbel, Helga; Jørgensen, Annemette

    Background In May 2015 we published a national clinical guideline on hysterectomy for benign gynaecological conditions in cooperation with the Danish Health and Medicines Authority. One of nine investigated areas of interest was whether or not to remove the fallopian tubes in women undergoing...... Network, the National Institute for Health and Care Excellence, the National Guideline Clearinghouse, the Scottish Intercollegiate Guidelines Network, the Health Technology Assessment Database, the Cochrane Library, MEDLINE, EMBASE, CINAHL and Danish, Swedish and Norwegian national directorates of health...

  8. Specialised care in patients undergoing pancreatoduodenectomy

    NARCIS (Netherlands)

    Tol, J.A.M.G.

    2014-01-01

    This thesis studies the controversies in the management of patients with pancreatic cancer undergoing pancreatoduodenectomy and determines different factors that will improve this management and thereby the postoperative outcomes. The studies were performed in both the pre-, peri- and postoperative

  9. A prospective assessment of renal oxygenation in children undergoing laparoscopy using near-infrared spectroscopy.

    Science.gov (United States)

    Westgarth-Taylor, Chris; de Lijster, Leonnie; van Bogerijen, Guido; Millar, Alastair J W; Karpelowsky, Jonathan

    2013-10-01

    This study was designed to determine whether a decrease in renal oxygenation occurs during CO2 pneumoperitoneum in children with normal renal function undergoing laparoscopy. Near infrared spectroscopy (NIRS) probes were applied to both the lateral flank (T10-L2) and lateral cerebral area of all patients with normal renal function undergoing a laparoscopic procedure. Information was recorded in 5-s intervals for 15-min before, during, and for 15-min after pneumoperitoneum insufflation and desufflation. Simultaneously, additional hemodynamic parameters (arterial saturation, mean arterial pressure, end tidal CO2, and urine output) were recorded every 5-min. Pneumoperitoneum pressures used were: 0-1 month old, anuria demonstrated in children undergoing laparoscopy.

  10. Macroecology of pollination networks

    DEFF Research Database (Denmark)

    Nielsen, Kristian Trøjelsgaard; Olesen, Jens Mogens

    2013-01-01

    Aim Interacting communities of species are organized into complex networks, and network analysis is reckoned to be a strong tool for describing their architecture. Many species assemblies show strong macroecological patterns, e.g. increasing species richness with decreasing latitude, but whether...... towards the tropics, and that network topology would be affected by current climate. Location Global. Methods Each network was organized as a presence/absence matrix, consisting of P plant species, A pollinator species and their links. From these matrices, network parameters were estimated. Additionally......, data about geography (latitude, elevation), climate at the network site (temperature, precipitation) and sampling effort (observation days) and extent (study-plot size) were gathered. Analyses were done using simultaneous autoregressive modelling (SAR). Results Species richness did not vary strongly...

  11. Simultaneous Endovascular Treatment of Ruptured Cerebral Aneurysms and Vasospasm

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Young Dae; Han, Moon Hee; Kang, Hyun Seung; Kim, Jeong Eun [Seoul National University Hospital, Seoul National University College of Medicine, Seoul (Korea, Republic of); Ahn, Jun Hyoung [Dept. of Neurosurgery, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang (Korea, Republic of); Jung, Seung Chai [Dept. of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul (Korea, Republic of); Kim, Chang Hun [Dept. of Neurology, Stroke Center, Myongji Hospital, Goyang (Korea, Republic of); Lim, Jeong Wook [Dept. of Neurosurgery, Sun Hospital, Daejeon (Korea, Republic of)

    2015-02-15

    The management of patients with ruptured cerebral aneurysms and severe vasospasm is subject to considerable controversy. We intended to describe herein an endovascular technique for the simultaneous treatment of aneurysms and vasospasm. A series of 11 patients undergoing simultaneous endovascular treatment of ruptured aneurysms and vasospasm were reviewed. After placement of a guiding catheter within the proximal internal carotid artery for coil embolization, an infusion line of nimodipine was wired to one hub, and of a microcatheter was advanced through another hub (to select and deliver detachable coils). Nimodipine was then infused continuously during the coil embolization. This technique was applied to 11 ruptured aneurysms accompanied by vasospasm (anterior communicating artery, 6 patients; internal carotid artery, 2 patients; posterior communicating and middle cerebral arteries, 1 patient each). Aneurysmal occlusion by coils and nimodipine-induced angioplasty were simultaneously achieved, resulting in excellent outcomes for all patients, and there were no procedure-related complications. Eight patients required repeated nimodipine infusions. Our small series of patients suggests that the simultaneous endovascular management of ruptured cerebral aneurysms and vasospasm is a viable approach in patients presenting with subarachnoid hemorrhage and severe vasospasm.

  12. From network structure to network reorganization: implications for adult neurogenesis

    Science.gov (United States)

    Schneider-Mizell, Casey M.; Parent, Jack M.; Ben-Jacob, Eshel; Zochowski, Michal R.; Sander, Leonard M.

    2010-12-01

    Networks can be dynamical systems that undergo functional and structural reorganization. One example of such a process is adult hippocampal neurogenesis, in which new cells are continuously born and incorporate into the existing network of the dentate gyrus region of the hippocampus. Many of these introduced cells mature and become indistinguishable from established neurons, joining the existing network. Activity in the network environment is known to promote birth, survival and incorporation of new cells. However, after epileptogenic injury, changes to the connectivity structure around the neurogenic niche are known to correlate with aberrant neurogenesis. The possible role of network-level changes in the development of epilepsy is not well understood. In this paper, we use a computational model to investigate how the structural and functional outcomes of network reorganization, driven by addition of new cells during neurogenesis, depend on the original network structure. We find that there is a stable network topology that allows the network to incorporate new neurons in a manner that enhances activity of the persistently active region, but maintains global network properties. In networks having other connectivity structures, new cells can greatly alter the distribution of firing activity and destroy the initial activity patterns. We thus find that new cells are able to provide focused enhancement of network only for small-world networks with sufficient inhibition. Network-level deviations from this topology, such as those caused by epileptogenic injury, can set the network down a path that develops toward pathological dynamics and aberrant structural integration of new cells.

  13. Steepest-Ascent Constrained Simultaneous Perturbation for Multiobjective Optimization

    DEFF Research Database (Denmark)

    McClary, Dan; Syrotiuk, Violet; Kulahci, Murat

    2011-01-01

    The simultaneous optimization of multiple responses in a dynamic system is challenging. When a response has a known gradient, it is often easily improved along the path of steepest ascent. On the contrary, a stochastic approximation technique may be used when the gradient is unknown or costly...... that leverages information about the known gradient to constrain the perturbations used to approximate the others. We apply SP(SA)(2) to the cross-layer optimization of throughput, packet loss, and end-to-end delay in a mobile ad hoc network (MANET), a self-organizing wireless network. The results show that SP...

  14. Envisioning Curriculum as Six Simultaneities

    Science.gov (United States)

    Hussain, Hanin; Conner, Lindsey; Mayo, Elaine

    2014-01-01

    This paper uses the discourse of complexity thinking to envision curriculum as six partial and coupled facets that exist simultaneously: curriculum as structure, curriculum as process, curriculum as content, curriculum as teaching, curriculum as learning and curriculum as activity. Such a curriculum is emergent and self-organising. It is emergent…

  15. Simultaneous stabilization using genetic algorithms

    Energy Technology Data Exchange (ETDEWEB)

    Benson, R.W.; Schmitendorf, W.E. (California Univ., Irvine, CA (USA). Dept. of Mechanical Engineering)

    1991-01-01

    This paper considers the problem of simultaneously stabilizing a set of plants using full state feedback. The problem is converted to a simple optimization problem which is solved by a genetic algorithm. Several examples demonstrate the utility of this method. 14 refs., 8 figs.

  16. Simultaneous interpreting: A cognitive perspective.

    NARCIS (Netherlands)

    Christoffels, I.K.; de Groot, A.M.

    2005-01-01

    Simultaneous interpreting (SI) is one of the most complex language tasks imaginable. During SI, one has to listen to and comprehend the input utterance in one language, keep it in working memory until it has been receded and can be produced in the other language, and produce the translation of an

  17. Experimental simulation of simultaneous vision.

    Science.gov (United States)

    de Gracia, Pablo; Dorronsoro, Carlos; Sánchez-González, Álvaro; Sawides, Lucie; Marcos, Susana

    2013-01-17

    To present and validate a prototype of an optical instrument that allows experimental simulation of pure bifocal vision. To evaluate the influence of different power additions on image contrast and visual acuity. The instrument provides the eye with two superimposed images, aligned and with the same magnification, but with different defocus states. Subjects looking through the instrument are able to experience pure simultaneous vision, with adjustable refractive correction and addition power. The instrument is used to investigate the impact of the amount of addition of an ideal bifocal simultaneous vision correction, both on image contrast and on visual performance. the instrument is validated through computer simulations of the letter contrast and by equivalent optical experiments with an artificial eye (camera). Visual acuity (VA) was measured in four subjects (AGE: 34.3 ± 3.4 years; spherical error: -2.1 ± 2.7 diopters [D]) for low and high contrast letters and different amounts of addition. The largest degradation in contrast and visual acuity (∼25%) occurred for additions around ±2 D, while additions of ±4 D produced lower degradation (14%). Low additions (1-2 D) result in lower VA than high additions (3-4 D). A simultaneous vision instrument is an excellent tool to simulate bifocal vision and to gain understanding of multifocal solutions for presbyopia. Simultaneous vision induces a pattern of visual performance degradation, which is well predicted by the degradation found in image quality. Neural effects, claimed to be crucial in the patients' tolerance of simultaneous vision, can be therefore compared with pure optical effects.

  18. Venous thromboembolic prophylaxis after simultaneous bilateral total knee arthroplasty: aspirinversuswarfarin.

    Science.gov (United States)

    Goel, R; Fleischman, A N; Tan, T; Sterbis, E; Huang, R; Higuera, C; Parvizi, J; Rothman, R H

    2018-01-01

    The aims of this study were to compare the efficacy of two agents, aspirin and warfarin, for the prevention of venous thromboembolism (VTE) after simultaneous bilateral total knee arthroplasty (SBTKA), and to elucidate the risk of VTE conferred by this procedure compared with unilateral TKA (UTKA). A retrospective, multi-institutional study was conducted on 18 951 patients, 3685 who underwent SBTKA and 15 266 who underwent UTKA, using aspirin or warfarin as VTE prophylaxis. Each patient was assigned an individualised baseline VTE risk score based on a system using the Nationwide Inpatient Sample. Symptomatic VTE, including pulmonary embolism (PE) and deep vein thrombosis (DVT), were identified in the first 90 days post-operatively. Statistical analyses were performed with logistic regression accounting for baseline VTE risk. The adjusted incidence of PE following SBTKA was 1.0% (95% confidence interval (CI) 0.86 to 1.2) with aspirin and 2.2% (95% CI 2.0 to 2.4) with warfarin. Similarly, the adjusted incidence of VTE following SBTKA was 1.6% (95% CI 1.1 to 2.3) with aspirin and 2.5% (95% CI 1.9 to 3.3) with warfarin. The risk of PE and VTE were reduced by 66% (odds ratio (OR) 0.44, 95% CI 0.25 to 0.78) and 38% (OR 0.62, 95% CI 0.38 to 1.0), respectively, using aspirin. In addition, the risk of PE was 204% higher for patients undergoing SBTKA relative to those undergoing UTKA. For each ten-point increase in baseline VTE risk, the risk of PE increased by 25.5% for patients undergoing SBTKA compared with 10.5% for those undergoing UTKA. Patients with a history of myocardial infarction or peripheral vascular disease had the greatest increase in risk from undergoing SBTKA instead of UTKA. Aspirin is more effective than warfarin for the prevention of VTE following SBTKA, and serves as the more appropriate agent for VTE prophylaxis for patients in all risk categories. Furthermore, patients undergoing SBTKA are at a substantially increased risk of VTE, even more so for

  19. Simultaneous PET and MR imaging

    Energy Technology Data Exchange (ETDEWEB)

    Yiping Shao; Cherry, Simon R.; Meadors, Ken; Siegel, Stefan; Silverman, Robert W. [Crump Institute for Biological Imaging, Department of Molecular and Medical Pharmacology, 10833 Le Conte Avenue, UCLA School of Medicine, Los Angeles, CA 90095 (United States); Farahani, Keyvan [Department of Radiological Sciences, 10833 Le Conte Avenue, UCLA School of Medicine, Los Angeles, CA 90095 (United States); Marsden, Paul K. [Guy' s and St Thomas' Clinical PET Centre, Division of Radiological Sciences, UMDS, London (United Kingdom)

    1997-10-01

    We have developed a prototype PET detector which is compatible with a clinical MRI system to provide simultaneous PET and MR imaging. This single-slice PET system consists of 48 2x2x10mm{sup 3} LSO crystals in a 38 mm diameter ring configuration that can be placed inside the receiver coil of the MRI system, coupled to three multi-channel photomultipliers housed outside the main magnetic field via 4 m long and 2 mm diameter optical fibres. The PET system exhibits 2 mm spatial resolution, 41% energy resolution at 511 keV and 20 ns timing resolution. Simultaneous PET and MR phantom images were successfully acquired. (author)

  20. From averaged to simultaneous controllability

    OpenAIRE

    Lohéac, Jérôme; Zuazua, Enrique

    2016-01-01

    International audience; We consider a linear finite dimensional control system depending on unknown parameters. We aim to design controls, independent of the parameters, to control the system in some optimal sense. We discuss the notions of averaged control, according to which one aims to control only the average of the states with respect to the unknown parameters, and the notion of simultaneous control in which the goal is to control the system for all values of these parameters. We show ho...

  1. Hidden neural networks

    DEFF Research Database (Denmark)

    Krogh, Anders Stærmose; Riis, Søren Kamaric

    1999-01-01

    A general framework for hybrids of hidden Markov models (HMMs) and neural networks (NNs) called hidden neural networks (HNNs) is described. The article begins by reviewing standard HMMs and estimation by conditional maximum likelihood, which is used by the HNN. In the HNN, the usual HMM probability...... parameters are replaced by the outputs of state-specific neural networks. As opposed to many other hybrids, the HNN is normalized globally and therefore has a valid probabilistic interpretation. All parameters in the HNN are estimated simultaneously according to the discriminative conditional maximum...... likelihood criterion. The HNN can be viewed as an undirected probabilistic independence network (a graphical model), where the neural networks provide a compact representation of the clique functions. An evaluation of the HNN on the task of recognizing broad phoneme classes in the TIMIT database shows clear...

  2. The robustness and restoration of a network of ecological networks.

    Science.gov (United States)

    Pocock, Michael J O; Evans, Darren M; Memmott, Jane

    2012-02-24

    Understanding species' interactions and the robustness of interaction networks to species loss is essential to understand the effects of species' declines and extinctions. In most studies, different types of networks (such as food webs, parasitoid webs, seed dispersal networks, and pollination networks) have been studied separately. We sampled such multiple networks simultaneously in an agroecosystem. We show that the networks varied in their robustness; networks including pollinators appeared to be particularly fragile. We show that, overall, networks did not strongly covary in their robustness, which suggests that ecological restoration (for example, through agri-environment schemes) benefitting one functional group will not inevitably benefit others. Some individual plant species were disproportionately well linked to many other species. This type of information can be used in restoration management, because it identifies the plant taxa that can potentially lead to disproportionate gains in biodiversity.

  3. Patients undergoing dacryocystorhinostomy surgery in northern Iran ...

    African Journals Online (AJOL)

    Background: Dacryocystorhinostomy (DCR) is widely accepted as the procedure of choice for surgical correction of lacrimal drainage system obstruction distal to common canaliculus in adulthood. Although, there are only limited epidemiological data available in Iran about the patients undergoing DCR surgery. Aim: This ...

  4. Experiences of patients undergoing chemotherapy - a qualitative ...

    African Journals Online (AJOL)

    Background: Cancer is a global public health challenge and how patients in countries with poor healthcare infrastructure experience cancer treatment is largely unknown. Purpose: The objective of this study was to describe adult Ugandan cancer patients' experiences of undergoing chemotherapy treatment. Methodology: ...

  5. Patients Undergoing Dacryocystorhinostomy Surgery in Northern ...

    African Journals Online (AJOL)

    such as age, and gender, clinical findings, history of surgery, etc., extracted from archived files of the patients undergoing ... between gender and dacryocystitis rate, it was high among female (P = 0.02( Most of the patients complained of ... at 3 months after surgery and a healed patent neo-ostium with a free flow of tears from ...

  6. Experiences of patients undergoing chemotherapy - a qualitative ...

    African Journals Online (AJOL)

    Purpose: The objective of this study was to describe adult Ugandan cancer patients' experiences of undergoing chemotherapy treatment. Methodology: Using a qualitative descriptive design, seven in-patients with varying cancer diagnoses at the Uganda Cancer ... tance of focusing research on persons with cancer in.

  7. Learning Networks, Networked Learning

    NARCIS (Netherlands)

    Sloep, Peter; Berlanga, Adriana

    2010-01-01

    Sloep, P. B., & Berlanga, A. J. (2011). Learning Networks, Networked Learning [Redes de Aprendizaje, Aprendizaje en Red]. Comunicar, XIX(37), 55-63. Retrieved from http://dx.doi.org/10.3916/C37-2011-02-05

  8. Service entity network virtualization architecture and model

    Science.gov (United States)

    Jin, Xue-Guang; Shou, Guo-Chu; Hu, Yi-Hong; Guo, Zhi-Gang

    2017-07-01

    Communication network can be treated as a complex network carrying a variety of services and service can be treated as a network composed of functional entities. There are growing interests in multiplex service entities where individual entity and link can be used for different services simultaneously. Entities and their relationships constitute a service entity network. In this paper, we introduced a service entity network virtualization architecture including service entity network hierarchical model, service entity network model, service implementation and deployment of service entity networks. Service entity network oriented multiplex planning model were also studied and many of these multiplex models were characterized by a significant multiplex of the links or entities in different service entity network. Service entity networks were mapped onto shared physical resources by dynamic resource allocation controller. The efficiency of the proposed architecture was illustrated in a simulation environment that allows for comparative performance evaluation. The results show that, compared to traditional networking architecture, this architecture has a better performance.

  9. A network of networks.

    Science.gov (United States)

    Iedema, Rick; Verma, Raj; Wutzke, Sonia; Lyons, Nigel; McCaughan, Brian

    2017-04-10

    Purpose To further our insight into the role of networks in health system reform, the purpose of this paper is to investigate how one agency, the NSW Agency for Clinical Innovation (ACI), and the multiple networks and enabling resources that it encompasses, govern, manage and extend the potential of networks for healthcare practice improvement. Design/methodology/approach This is a case study investigation which took place over ten months through the first author's participation in network activities and discussions with the agency's staff about their main objectives, challenges and achievements, and with selected services around the state of New South Wales to understand the agency's implementation and large system transformation activities. Findings The paper demonstrates that ACI accommodates multiple networks whose oversight structures, self-organisation and systems change approaches combined in dynamic ways, effectively yield a diversity of network governances. Further, ACI bears out a paradox of "centralised decentralisation", co-locating agents of innovation with networks of implementation and evaluation expertise. This arrangement strengthens and legitimates the role of the strategic hybrid - the healthcare professional in pursuit of change and improvement, and enhances their influence and impact on the wider system. Research limitations/implications While focussing the case study on one agency only, this study is unique as it highlights inter-network connections. Contributing to the literature on network governance, this paper identifies ACI as a "network of networks" through which resources, expectations and stakeholder dynamics are dynamically and flexibly mediated and enhanced. Practical implications The co-location of and dynamic interaction among clinical networks may create synergies among networks, nurture "strategic hybrids", and enhance the impact of network activities on health system reform. Social implications Network governance requires more

  10. Sequential versus simultaneous market delineation

    DEFF Research Database (Denmark)

    Haldrup, Niels; Møllgaard, Peter; Kastberg Nielsen, Claus

    2005-01-01

    and geographical markets. Using a unique data setfor prices of Norwegian and Scottish salmon, we propose a methodologyfor simultaneous market delineation and we demonstrate that comparedto a sequential approach conclusions will be reversed.JEL: C3, K21, L41, Q22Keywords: Relevant market, econometric delineation......Delineation of the relevant market forms a pivotal part of most antitrustcases. The standard approach is sequential. First the product marketis delineated, then the geographical market is defined. Demand andsupply substitution in both the product dimension and the geographicaldimension...

  11. Applying Physical-Layer Network Coding in Wireless Networks

    Directory of Open Access Journals (Sweden)

    Liew SoungChang

    2010-01-01

    Full Text Available A main distinguishing feature of a wireless network compared with a wired network is its broadcast nature, in which the signal transmitted by a node may reach several other nodes, and a node may receive signals from several other nodes, simultaneously. Rather than a blessing, this feature is treated more as an interference-inducing nuisance in most wireless networks today (e.g., IEEE 802.11. This paper shows that the concept of network coding can be applied at the physical layer to turn the broadcast property into a capacity-boosting advantage in wireless ad hoc networks. Specifically, we propose a physical-layer network coding (PNC scheme to coordinate transmissions among nodes. In contrast to "straightforward" network coding which performs coding arithmetic on digital bit streams after they have been received, PNC makes use of the additive nature of simultaneously arriving electromagnetic (EM waves for equivalent coding operation. And in doing so, PNC can potentially achieve 100% and 50% throughput increases compared with traditional transmission and straightforward network coding, respectively, in 1D regular linear networks with multiple random flows. The throughput improvements are even larger in 2D regular networks: 200% and 100%, respectively.

  12. Aspirin in patients undergoing noncardiac surgery

    DEFF Research Database (Denmark)

    Devereaux, P J; Mrkobrada, Marko; Sessler, Daniel I

    2014-01-01

    BACKGROUND: There is substantial variability in the perioperative administration of aspirin in patients undergoing noncardiac surgery, both among patients who are already on an aspirin regimen and among those who are not. METHODS: Using a 2-by-2 factorial trial design, we randomly assigned 10......,010 patients who were preparing to undergo noncardiac surgery and were at risk for vascular complications to receive aspirin or placebo and clonidine or placebo. The results of the aspirin trial are reported here. The patients were stratified according to whether they had not been taking aspirin before...... the study (initiation stratum, with 5628 patients) or they were already on an aspirin regimen (continuation stratum, with 4382 patients). Patients started taking aspirin (at a dose of 200 mg) or placebo just before surgery and continued it daily (at a dose of 100 mg) for 30 days in the initiation stratum...

  13. Simultaneous optimization of dynamic bioprocesses

    Directory of Open Access Journals (Sweden)

    Riascos C.A.M.

    2002-01-01

    Full Text Available It is known that the optimal control may introduce significant economical benefits into production processes, thus being an important and challenging research area with practical relevance. The modeling and optimization of biotechnological processes has been object of research and their related results have generated improvements in operating conditions and strategies, however, the inherent features of dynamical bioprocesses prevent the application of conventional optimization algorithms, hence making necessary the development of tailored methods and strategies. The objective of this work is to develop mathematical programming strategies for simultaneous optimization of dynamic systems and evaluate their computational performance. Simultaneous optimization with orthogonal collocation is applied to a simplified model for biosynthesis of penicillin from glucose, which was studied by Cuthrell and Biegler (1989. The results show that discretization of differential equations systems (DAE by orthogonal collocation in finite elements efficiently transforms dynamic optimization problems into nonlinear programming (NLP problems, enabling to solve complex problems with several control variables and minimizing the approximation error.

  14. Structured plant metabolomics for the simultaneous exploration of multiple factors

    Science.gov (United States)

    Vasilev, Nikolay; Boccard, Julien; Lang, Gerhard; Grömping, Ulrike; Fischer, Rainer; Goepfert, Simon; Rudaz, Serge; Schillberg, Stefan

    2016-01-01

    Multiple factors act simultaneously on plants to establish complex interaction networks involving nutrients, elicitors and metabolites. Metabolomics offers a better understanding of complex biological systems, but evaluating the simultaneous impact of different parameters on metabolic pathways that have many components is a challenging task. We therefore developed a novel approach that combines experimental design, untargeted metabolic profiling based on multiple chromatography systems and ionization modes, and multiblock data analysis, facilitating the systematic analysis of metabolic changes in plants caused by different factors acting at the same time. Using this method, target geraniol compounds produced in transgenic tobacco cell cultures were grouped into clusters based on their response to different factors. We hypothesized that our novel approach may provide more robust data for process optimization in plant cell cultures producing any target secondary metabolite, based on the simultaneous exploration of multiple factors rather than varying one factor each time. The suitability of our approach was verified by confirming several previously reported examples of elicitor–metabolite crosstalk. However, unravelling all factor–metabolite networks remains challenging because it requires the identification of all biochemically significant metabolites in the metabolomics dataset. PMID:27853298

  15. Jejunostomy tube feeding in patients undergoing esophagectomy.

    Science.gov (United States)

    Srinathan, Sadeesh K; Hamin, Tamara; Walter, Stephen; Tan, A Lawrence; Unruh, Helmut W; Guyatt, Gordon

    2013-12-01

    Surgical jejunostomy tubes are a routine part of elective esophagectomies in patients with carcinomas and provide a route for nutritional support in those who experience complications. We wished to determine how frequently oral intake is delayed and the amount of nutrition delivered via the jejunostomy tube. We reviewed the charts of all adults undergoing esophagectomy for carcinoma between January 2000 and June 2008. We determined the proportion of patients unable to resume oral nutrition after 8 days and the amount of nutrition delivered in each of the 8 days. In all, 111 patients underwent elective esophagectomy for carcinoma, and 103 had a jejunostomy tube placed. The mean age was 67 ± 10.8 years. The median time to oral intake was 7 (interquartile range 7-11) days. Seventy-four (67%) patients resumed oral intake within 8 days. The mean nutrition delivered by jejunostomy within the first 8 days as a percentage of the target was 45.6% (95% confidence interval 41.2%-49.9%). Six (5.4%) patients experienced complications attributable solely to the jejunostomy tube; 3 (2.9%) required surgery. Forty (38.8%) patients had abdominal issues serious enough to warrant delaying the progression of feeding. Two-thirds of patients undergoing elective esophagectomy were tolerating oral intake by the end of the eighth postoperative day, and less than half of the target nutrition was delivered over the first 8 days. We now selectively place surgical jejunostomy tubes in patients undergoing elective esophagectomies.

  16. Anesthesia Mangement in Simultaneously Coronary Artery By-Pass Grefting and Lobectomy Surgery: Case Report

    Directory of Open Access Journals (Sweden)

    Gokhan Ozkan

    2014-08-01

    Full Text Available Recently, cardio-pulmonary surgical procedures were simultaneously performed in patients with coronary artery disease and lung tumors. There is no complete consensus about the timing of these high rate mortality and morbidity surgery. Similarly, there wasn%u2019t any large number clinical trial related to the anesthetic management of these patients except case reports and clinical experiences. In this case report, we aim to present anesthesia management in a 89-year-old male patient undergoing simultaneous cardio-pulmonary surgery.

  17. Genetic Algorithm Optimized Neural Networks Ensemble as ...

    African Journals Online (AJOL)

    NJD

    Genetic Algorithm Optimized Neural Networks Ensemble as. Calibration Model for Simultaneous Spectrophotometric. Estimation of Atenolol and Losartan Potassium in Tablets. Dondeti Satyanarayana*, Kamarajan Kannan and Rajappan Manavalan. Department of Pharmacy, Annamalai University, Annamalainagar, Tamil ...

  18. Outcomes of Simultaneous Liver Kidney Transplantation in Patients With Hepatocellular Carcinoma.

    Science.gov (United States)

    Rich, Nicole; Tanriover, Bekir; Singal, Amit G; Marrero, Jorge A

    2017-01-01

    The frequency of simultaneous liver kidney (SLK) transplantation has increased following the implementation of the model for end-stage liver disease system for liver transplantation (LT). There is a paucity of data evaluating SLK outcomes in patients undergoing LT for hepatocellular carcinoma (HCC). Our aim was to compare outcomes between patients with HCC who underwent SLK and those who received SLK for other indications. We performed a retrospective analysis of adult recipients receiving SLK between 2002 and 2013 from the United Network for Organ Sharing registry. The primary outcome was posttransplant mortality. Patient survival was determined using Kaplan-Meier analysis and predictors of mortality were identified using proportional Cox hazard regression models. Propensity score matching was performed between SLK-HCC and SLK in the absence of HCC (SLK-A) groups to reduce confounding. Between 2002 and 2013, 186 HCC patients underwent SLK-HCC and 3599 patients underwent SLK-A. The 1-year and 3-year survival rates were 89.0% and 76.7% in the SLK-HCC group and 84.5% and 76.3% in the SLK-A group (P = 0.20). In multivariable Cox regression, HCC was not associated with post-LT survival among all patients (hazard ratio, 1.15; 95% confidence interval, 0.84-1.58) or the propensity score-matched cohort (hazard ratio, 0.97; 95% confidence interval, 0.64-1.47). SLK-HCC patients had similar rates of acute rejection (13.3% vs 10.5%, P = 0.36) and liver graft failure requiring re-transplantation (3.2% vs 2.3%, P = 0.44) compared with SLK-A patients. Liver transplant candidates with advanced renal dysfunction and HCC may be considered for SLK.

  19. Simultaneous learning of two languages from birth positively impacts intrinsic functional connectivity and cognitive control.

    Science.gov (United States)

    Kousaie, Shanna; Chai, Xiaoqian J; Sander, Kaija M; Klein, Denise

    2017-10-01

    This study explores the effect of individual differences in the age of acquisition of a second language using resting-state functional magnetic resonance imaging (rs-fMRI) to examine functional connectivity and its relation with cognitive control within bilinguals. We compared simultaneous bilinguals, who learned two languages from birth, to sequential bilinguals, who learned a second language following mastery of their first language. Results show an effect of language experience on the strength of anticorrelation between the default mode network and the task-positive attention network and on cognitive control, with simultaneous bilinguals demonstrating stronger anticorrelations between the two networks, as well as superior cognitive control compared to sequential bilinguals. These findings demonstrate that the timing of language learning may have an impact on cognitive control, with the simultaneous learning of two languages being associated with more optimal brain connectivity for cognitive control compared to sequential language learning. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. Simultaneous shoulder and elbow dislocation.

    Science.gov (United States)

    Cobanoğlu, Mutlu; Yumrukcal, Feridun; Karataş, Cengiz; Duygun, Fatih

    2014-05-23

    Ipsilateral shoulder and elbow dislocation is very rare and only six articles are present in the literature mentioning this kind of a complex injury. With this presentation we aim to emphasise the importance of assessing the adjacent joints in patients with trauma in order not to miss any accompanying pathologies. We report a case of a 43-year-old female patient with ipsilateral right shoulder and elbow dislocation treated conservatively. The patient reported elbow pain when first admitted to emergency service but she was diagnosed with simultaneous ipsilateral shoulder and elbow injury and treated conservatively. As a more painful pathology may mask the additional ones, one should hasten to help before performing a complete evaluation. Any harm caused to the patient due to this reason would not be a complication but a malpractice. 2014 BMJ Publishing Group Ltd.

  1. End results of simultaneous pancreatectomy, splenectomy and total gastrectomy for patients with gastric carcinoma.

    OpenAIRE

    Otsuji, E; Yamaguchi, T.; Sawai, K.; Okamoto, K.; Takahashi, T.

    1997-01-01

    A distal pancreatectomy is often performed simultaneously with splenectomy and total gastrectomy in the treatment of gastric carcinoma to facilitate dissection of the lymph nodes around the splenic artery. However, the morbidity of partial pancreatectomy is high. Patients undergoing pancreaticosplenectomy in conjunction with total gastrectomy are subject to leaks from the pancreatic stump, which may cause further complications. We performed a retrospective analysis to evaluate the end results...

  2. Speech profile of patients undergoing primary palatoplasty.

    Science.gov (United States)

    Menegueti, Katia Ignacio; Mangilli, Laura Davison; Alonso, Nivaldo; Andrade, Claudia Regina Furquim de

    2017-10-26

    To characterize the profile and speech characteristics of patients undergoing primary palatoplasty in a Brazilian university hospital, considering the time of intervention (early, before two years of age; late, after two years of age). Participants were 97 patients of both genders with cleft palate and/or cleft and lip palate, assigned to the Speech-language Pathology Department, who had been submitted to primary palatoplasty and presented no prior history of speech-language therapy. Patients were divided into two groups: early intervention group (EIG) - 43 patients undergoing primary palatoplasty before 2 years of age and late intervention group (LIG) - 54 patients undergoing primary palatoplasty after 2 years of age. All patients underwent speech-language pathology assessment. The following parameters were assessed: resonance classification, presence of nasal turbulence, presence of weak intraoral air pressure, presence of audible nasal air emission, speech understandability, and compensatory articulation disorder (CAD). At statistical significance level of 5% (p≤0.05), no significant difference was observed between the groups in the following parameters: resonance classification (p=0.067); level of hypernasality (p=0.113), presence of nasal turbulence (p=0.179); presence of weak intraoral air pressure (p=0.152); presence of nasal air emission (p=0.369), and speech understandability (p=0.113). The groups differed with respect to presence of compensatory articulation disorders (p=0.020), with the LIG presenting higher occurrence of altered phonemes. It was possible to assess the general profile and speech characteristics of the study participants. Patients submitted to early primary palatoplasty present better speech profile.

  3. Thromboprophylaxis for women undergoing caesarean section.

    LENUS (Irish Health Repository)

    Kennedy, C

    2012-02-01

    Thromboprophylaxis for women undergoing caesarean section (CS) was introduced in the hospital in 1995. This study audited the use of tinzaparin prophylaxis in a nested cohort of women who screened negative for diabetes mellitus at 28 weeks gestation. All the women had their weight measured and BMI calculated at the first antenatal visit. Of the 284 women, 68 (24%) had a CS and all received tinzaparin. Of the 68, however, 94% received a dose lower than recommended. Compliance with prophylaxis was complete but compliance with the recommended dosage was suboptimal, which may result in venous thromboembolism after CS despite thromboprophylaxis.

  4. Dermatillomania: In patient undergoing orthodontic treatment

    Directory of Open Access Journals (Sweden)

    Adit

    2014-01-01

    Full Text Available Dermatillomania is a disorder in which a person habitually picks their skin, and this is a form of self-injury. It can involve any part of the body, but usually involves the face, neck, arms and shoulders. Symptoms often follow an event that has caused severe emotional distress. A dermatillomania or compulsive skin picking episode may be a conscious response to anxiety or depression but is frequently done as an unconscious habit. In this case report, a patient undergoing orthodontic treatment was found to be suffering from dermatillomania and was treated using psychological counseling.

  5. Oral surgery in patients undergoing chemoradiation therapy.

    Science.gov (United States)

    Demian, Nagi M; Shum, Jonathan W; Kessel, Ivan L; Eid, Ahmed

    2014-05-01

    Oral health care in patients undergoing chemotherapy and/or radiation therapy can be complex. Care delivered by a multidisciplinary approach is timely and streamlines the allocation of resources to provide prompt care and to attain favorable outcomes. A hospital dentist, oral and maxillofacial surgeon, and a maxillofacial prosthodontist must be involved early to prevent avoidable oral complications. Prevention and thorough preparation are vital before the start of chemotherapy and radiation therapy. Oral complications must be addressed immediately and, even with the best management, can cause delays and interruption in treatment, with serious consequences for the outcome and prognosis. Copyright © 2014 Elsevier Inc. All rights reserved.

  6. Stochastic Trade Networks

    OpenAIRE

    Massimo Riccaboni; Stefano Schiavo

    2013-01-01

    This paper develops a simple network model to describe the dynamic of the intensive and extensive margin of international trade flows. The result is achieved by means of the combination of two mechanisms of proportional growth: the first (discrete) determines the formation of trade links, the second (continuous) governs trade intensity. We show that our setup is able to simultaneously match a large number of empirical regularities, such as the fraction of zero trade flows across pairs of coun...

  7. Simultaneous seeing measurements at Atacama

    Science.gov (United States)

    Uraguchi, Fumihiro; Motohara, Kentaro; Doi, Mamoru; Takato, Naruhisa; Miyashita, Akihiko; Tanabe, Toshihiko; Oyabu, Shinki; Soyano, Takao

    2004-10-01

    Institute of Astronomy, University of Tokyo is now planning to build a 6.5-m optical-infrared telescope in Atacama, Chile. This project is called "Univ. Tokyo Atacama Observatory (TAO)", and the site evaluation is now under way. As a part of this evaluation process, we started an investigation to compare the astronomical seeing at Atacama with that at Mauna Kea. Here, we report preliminary results of seeing measurements at several sites in Atacama, carried out on October 2003. In order to separate the temporal and site-to-site variation of the seeing, we used two sets of Differential Image Motion Monitors (DIMMs), each of which has two pairs of 7.4 cm sub-apertures with 20.5 cm separation. Three sites were investigated; the point near the TAO weather station (4,950m), the summit of Cello Chico (5,150m) and the point at 5,430m altitude on Cello Toco. Simultaneous measurements were carried out for three half nights out of four half nights measurements. Although the amount of our data is very limited, the results suggest following: 1) Seeing becomes better and more stable as time passing to midnight (eg. From 0."7 to 0."4 at V-band). 2) Higher altitude sites show better seeing than lower altitude sites.

  8. A Survey on Simultaneous Wireless Information and Power Transfer

    Science.gov (United States)

    Perera, T. D. P.; Jayakody, D. N. K.; De, S.; Ivanov, M. A.

    2017-01-01

    This paper presents a comprehensive study related to simultaneous wireless information and power transfer (SWIPT) in different types of wireless communication setups. Harvesting energy using SWIPT is an appealing solution in the context of extending battery life of wireless devices for a fully sustainable communication system. Strong signal power increases power transfer, but also causes more interference in information transfer, causing realization of the SWIPT challenging problem. This article provides an overview of technical evolution of SWIPT. A survey and qualitative comparison of the existing SWIPT schemes is provided to demonstrate their limitations in the current and 5G networks. Open challenges are emphasized and guidelines are provided to adapt the existing schemes in order to overcome these limitations and make them fit for integrating with the modern and emerging next generation communication networks, such as 5G systems.

  9. Can neural machine translation do simultaneous translation?

    OpenAIRE

    Cho, Kyunghyun; Esipova, Masha

    2016-01-01

    We investigate the potential of attention-based neural machine translation in simultaneous translation. We introduce a novel decoding algorithm, called simultaneous greedy decoding, that allows an existing neural machine translation model to begin translating before a full source sentence is received. This approach is unique from previous works on simultaneous translation in that segmentation and translation are done jointly to maximize the translation quality and that translating each segmen...

  10. Declarative Networking

    CERN Document Server

    Loo, Boon Thau

    2012-01-01

    Declarative Networking is a programming methodology that enables developers to concisely specify network protocols and services, which are directly compiled to a dataflow framework that executes the specifications. Declarative networking proposes the use of a declarative query language for specifying and implementing network protocols, and employs a dataflow framework at runtime for communication and maintenance of network state. The primary goal of declarative networking is to greatly simplify the process of specifying, implementing, deploying and evolving a network design. In addition, decla

  11. Discovering network structure beyond communities.

    Science.gov (United States)

    Nishikawa, Takashi; Motter, Adilson E

    2011-01-01

    To understand the formation, evolution, and function of complex systems, it is crucial to understand the internal organization of their interaction networks. Partly due to the impossibility of visualizing large complex networks, resolving network structure remains a challenging problem. Here we overcome this difficulty by combining the visual pattern recognition ability of humans with the high processing speed of computers to develop an exploratory method for discovering groups of nodes characterized by common network properties, including but not limited to communities of densely connected nodes. Without any prior information about the nature of the groups, the method simultaneously identifies the number of groups, the group assignment, and the properties that define these groups. The results of applying our method to real networks suggest the possibility that most group structures lurk undiscovered in the fast-growing inventory of social, biological, and technological networks of scientific interest.

  12. On Identities in Modern Networks

    Directory of Open Access Journals (Sweden)

    Libor Polcak

    2014-09-01

    Full Text Available Communicating parties inside computer networks use different kind of identifiers. Some of these identifiers are stable, e.g., logins used to access a specific service, some are only temporary, e.g., dynamically assigned IP addresses. This paper tackles several challenges of lawful interception that emerged in modern networks. The main contribution is the graph model that links identities learnt from various sources distributed in a network. The inferred identities result into an interception of more detailed data in conformance with the issued court order. The approach deals with network address translation, short-lived identifiers and simultaneous usage of different identities. The approach was evaluated to be viable during real network testing based on various means to learn identities of users connected to a network.

  13. Pectus excavatum and cardiac surgery: simultaneous correction advocated.

    Science.gov (United States)

    Schmidt, Joachim; Redwan, Bassam; Koesek, Volkan; Aebert, Hermann; Tjan, Tonny Djie-Tiong; Martens, Sven; Wiebe, Karsten

    2014-04-01

    Severe pectus excavatum may be present in combination with cardiac conditions requiring open-heart surgery. The best strategy for this situation has been debated controversially. In a retrospective study, we analyzed all our patients undergoing concurrent pectus excavatum correction and open-heart surgery. Ten patients aged 9 to 70 years underwent a simultaneous combined surgical procedure between 2001 and 2013. Indications for cardiac surgery were various forms of congenital and acquired heart disease including coronary artery disease with internal thoracic artery grafts and ascending aortic aneurysms. A modified Ravitch procedure was performed for pectus excavatum correction (mean Haller-Index 5.0). Mean operating time was 364 (210-495) minutes and mean duration of cardiopulmonary bypass was 125 (54-222) minutes. All procedures were completed successfully. Postoperatively minor complications were observed in three patients. In-hospital and 30-day mortalities were nil. Good cosmetic and functional results were achieved in all patients. Our data demonstrate that simultaneous pectus excavatum correction and cardiac surgery is effective and reliable. A combined approach is advocated if candidates for cardiac surgery present with significant pectus excavatum deformity. Georg Thieme Verlag KG Stuttgart · New York.

  14. [Nutritional status of patients undergoing peritoneal dialysis].

    Science.gov (United States)

    Bober, Joanna; Mazur, Olech; Gołembiewska, Edyta; Bogacka, Anna; Sznabel, Karina; Stańkowska-Walczak, Dobrosława; Kabat-Koperska, Joanna; Stachowska, Ewa

    2015-01-01

    The main causes of death in patients undergoing dialysis are cardiovascular diseases. Their presence is related to the nutritional status of patients treated with peritoneal dialysis, and has a predicted value in this kind of patient. Long-term therapy entails unfavourable changes, from which a clinically significant complication is protein-energy malnutrition and intensification of inflammatory processes. The aim of the study was to assess the nutritional status of patients with chronic kidney disease treated with peritoneal dialysis based on anthropometric, biochemical parameters analysis, a survey, as well as the determination of changes in measured parameters occurring over time. The study involved 40 people undergoing peritoneal dialysis (PD) and 30 healthy people. For dialyzed patients testing material was collected twice, every 6 months. Proteins, albumins, prealbumins, C-reactive protein and glucose levels were measured. Anthropometric measurements included body height, body weight, triceps skinfold and subscapular skinfold thickness. Body mass index (BMI) value and exponent of tissue protein source were calculated. The examined patients completed the questionnaire, which included, among other factors, the daily intake of nutrients, and lifestyle information. During the 6 month observation of the PD group a stastically significant increase in the energy value of intake food and amount of calories intake from carbohydrates was found. Analysis of nutritional status dependent on the BMI showed that overweight and obese patients are characterized by higher concentrations of the C-reactive protein and glucose, as well as lower concentrations of prealbumin compared to patients with normal body weight. At the same time, the energy value of food and the amount of protein in the group with BMI > 25 were smaller than in the other groups. During the 6 month observation a decrease the concentration of prealbumin and an increase in C-reactive protein in BMI > 25 group

  15. Bladder function in patients with dystonia undergoing deep brain stimulation.

    Science.gov (United States)

    Mordasini, Livio; Kessler, Thomas M; Kiss, Bernhard; Schüpbach, Michael; Pollo, Claudio; Kaelin-Lang, Alain

    2014-09-01

    Neurogenic bladder dysfunction is well described in Parkinson's disease and has a major impact on quality of live. In contrast, little is known about the extent of urinary symptoms in other movement disorders such as dystonia and about the role of the basal ganglia in bladder control.. A consecutive series of 11 patients with severe dystonia undergoing deep brain stimulation (DBS) of the globus pallidus internus was prospectively enrolled. Bladder function was assessed by the International Prostate Symptom Score and urodynamic investigation (UDI) before DBS surgery and afterwards in the conditions with and without DBS. In UDI before DBS surgery, detrusor overactivity was found in 36% (4/11) of dystonia patients. With pallidal DBS ON, maximum flow rate significantly decreased, post-void residual significantly increased and detrusor overactivity disappeared.. Pathological urodynamic changes can be found in a relevant percentage of dystonia patients. Pallidal DBS has a relaxing effect on detrusor function indicating a role of the basal ganglia in lower urinary tract control. Thus, a better understanding on how subcortical networks influence lower urinary tract function might open new therapeutic perspectives.. Copyright © 2014 Elsevier Ltd. All rights reserved.

  16. Thermodynamics of a qubit undergoing dephasing

    Science.gov (United States)

    Marcantoni, S.

    2017-05-01

    The thermodynamics of a qubit undergoing dephasing due to the coupling with the external environment is discussed. First of all, we assume the dynamics of the system to be described by a master equation in Lindblad form. In this framework, we review a standard formulation of the first and second law of thermodynamics that has been known in literature for a long time. After that, we explicitly model the environment with a set of quantum harmonic oscillators choosing the interaction such that the global dynamics of system and bath is analytically solvable and the Lindblad master equation is recovered in the weak-coupling limit. In this generalized setting, we can show that the correlations between system and bath play a fundamental role in the heat exchange. Moreover, the internal entropy production of the qubit is proven to be positive for arbitrary coupling strength.

  17. Trinets encode tree-child and level-2 phylogenetic networks

    NARCIS (Netherlands)

    L.J.J. van Iersel (Leo); V. Moulton

    2012-01-01

    htmlabstractPhylogenetic networks generalize evolutionary trees, and are commonly used to represent evolutionary histories of species that undergo reticulate evolutionary processes such as hybridization, recombination and lateral gene transfer. Recently, there has been great interest in trying to

  18. Genetic Algorithm Optimized Neural Networks Ensemble as ...

    African Journals Online (AJOL)

    Improvements in neural network calibration models by a novel approach using neural network ensemble (NNE) for the simultaneous spectrophotometric multicomponent analysis are suggested, with a study on the estimation of the components of an antihypertensive combination, namely, atenolol and losartan potassium.

  19. The ubiquity of small-world networks.

    Science.gov (United States)

    Telesford, Qawi K; Joyce, Karen E; Hayasaka, Satoru; Burdette, Jonathan H; Laurienti, Paul J

    2011-01-01

    Small-world networks, according to Watts and Strogatz, are a class of networks that are "highly clustered, like regular lattices, yet have small characteristic path lengths, like random graphs." These characteristics result in networks with unique properties of regional specialization with efficient information transfer. Social networks are intuitive examples of this organization, in which cliques or clusters of friends being interconnected but each person is really only five or six people away from anyone else. Although this qualitative definition has prevailed in network science theory, in application, the standard quantitative application is to compare path length (a surrogate measure of distributed processing) and clustering (a surrogate measure of regional specialization) to an equivalent random network. It is demonstrated here that comparing network clustering to that of a random network can result in aberrant findings and that networks once thought to exhibit small-world properties may not. We propose a new small-world metric, ω (omega), which compares network clustering to an equivalent lattice network and path length to a random network, as Watts and Strogatz originally described. Example networks are presented that would be interpreted as small-world when clustering is compared to a random network but are not small-world according to ω. These findings have important implications in network science because small-world networks have unique topological properties, and it is critical to accurately distinguish them from networks without simultaneous high clustering and short path length.

  20. Loudness estimation of simultaneous sources using beamforming

    DEFF Research Database (Denmark)

    Song, Woo-keun; Ellermeier, Wolfgang; Minnaar, Pauli

    2006-01-01

    An algorithm is proposed for estimating the loudness of several simultaneous sound sources by means of microphone-array beamforming. The algorithm is derived from two listening experiments in which the loudness of two simultaneous sounds (narrow-band noises with 1-kHz and 3.15-kHz center frequenc...

  1. 5 CFR 1651.11 - Simultaneous death.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Simultaneous death. 1651.11 Section 1651.11 Administrative Personnel FEDERAL RETIREMENT THRIFT INVESTMENT BOARD DEATH BENEFITS § 1651.11 Simultaneous death. If a beneficiary dies at the same time as the participant, the beneficiary will be treated...

  2. Attractor metabolic networks.

    Science.gov (United States)

    De la Fuente, Ildefonso M; Cortes, Jesus M; Pelta, David A; Veguillas, Juan

    2013-01-01

    The experimental observations and numerical studies with dissipative metabolic networks have shown that cellular enzymatic activity self-organizes spontaneously leading to the emergence of a Systemic Metabolic Structure in the cell, characterized by a set of different enzymatic reactions always locked into active states (metabolic core) while the rest of the catalytic processes are only intermittently active. This global metabolic structure was verified for Escherichia coli, Helicobacter pylori and Saccharomyces cerevisiae, and it seems to be a common key feature to all cellular organisms. In concordance with these observations, the cell can be considered a complex metabolic network which mainly integrates a large ensemble of self-organized multienzymatic complexes interconnected by substrate fluxes and regulatory signals, where multiple autonomous oscillatory and quasi-stationary catalytic patterns simultaneously emerge. The network adjusts the internal metabolic activities to the external change by means of flux plasticity and structural plasticity. In order to research the systemic mechanisms involved in the regulation of the cellular enzymatic activity we have studied different catalytic activities of a dissipative metabolic network under different external stimuli. The emergent biochemical data have been analysed using statistical mechanic tools, studying some macroscopic properties such as the global information and the energy of the system. We have also obtained an equivalent Hopfield network using a Boltzmann machine. Our main result shows that the dissipative metabolic network can behave as an attractor metabolic network. We have found that the systemic enzymatic activities are governed by attractors with capacity to store functional metabolic patterns which can be correctly recovered from specific input stimuli. The network attractors regulate the catalytic patterns, modify the efficiency in the connection between the multienzymatic complexes, and stably

  3. Attractor metabolic networks.

    Directory of Open Access Journals (Sweden)

    Ildefonso M De la Fuente

    Full Text Available BACKGROUND: The experimental observations and numerical studies with dissipative metabolic networks have shown that cellular enzymatic activity self-organizes spontaneously leading to the emergence of a Systemic Metabolic Structure in the cell, characterized by a set of different enzymatic reactions always locked into active states (metabolic core while the rest of the catalytic processes are only intermittently active. This global metabolic structure was verified for Escherichia coli, Helicobacter pylori and Saccharomyces cerevisiae, and it seems to be a common key feature to all cellular organisms. In concordance with these observations, the cell can be considered a complex metabolic network which mainly integrates a large ensemble of self-organized multienzymatic complexes interconnected by substrate fluxes and regulatory signals, where multiple autonomous oscillatory and quasi-stationary catalytic patterns simultaneously emerge. The network adjusts the internal metabolic activities to the external change by means of flux plasticity and structural plasticity. METHODOLOGY/PRINCIPAL FINDINGS: In order to research the systemic mechanisms involved in the regulation of the cellular enzymatic activity we have studied different catalytic activities of a dissipative metabolic network under different external stimuli. The emergent biochemical data have been analysed using statistical mechanic tools, studying some macroscopic properties such as the global information and the energy of the system. We have also obtained an equivalent Hopfield network using a Boltzmann machine. Our main result shows that the dissipative metabolic network can behave as an attractor metabolic network. CONCLUSIONS/SIGNIFICANCE: We have found that the systemic enzymatic activities are governed by attractors with capacity to store functional metabolic patterns which can be correctly recovered from specific input stimuli. The network attractors regulate the catalytic patterns

  4. The network researchers' network

    DEFF Research Database (Denmark)

    Henneberg, Stephan C.; Jiang, Zhizhong; Naudé, Peter

    2009-01-01

    The Industrial Marketing and Purchasing (IMP) Group is a network of academic researchers working in the area of business-to-business marketing. The group meets every year to discuss and exchange ideas, with a conference having been held every year since 1984 (there was no meeting in 1987). In thi......The Industrial Marketing and Purchasing (IMP) Group is a network of academic researchers working in the area of business-to-business marketing. The group meets every year to discuss and exchange ideas, with a conference having been held every year since 1984 (there was no meeting in 1987......). In this paper, based upon the papers presented at the 22 conferences held to date, we undertake a Social Network Analysis in order to examine the degree of co-publishing that has taken place between this group of researchers. We identify the different components in this database, and examine the large main...

  5. The Application of Social Network Analysis to Team Sports

    Science.gov (United States)

    Lusher, Dean; Robins, Garry; Kremer, Peter

    2010-01-01

    This article reviews how current social network analysis might be used to investigate individual and group behavior in sporting teams. Social network analysis methods permit researchers to explore social relations between team members and their individual-level qualities simultaneously. As such, social network analysis can be seen as augmenting…

  6. Network cosmology.

    Science.gov (United States)

    Krioukov, Dmitri; Kitsak, Maksim; Sinkovits, Robert S; Rideout, David; Meyer, David; Boguñá, Marián

    2012-01-01

    Prediction and control of the dynamics of complex networks is a central problem in network science. Structural and dynamical similarities of different real networks suggest that some universal laws might accurately describe the dynamics of these networks, albeit the nature and common origin of such laws remain elusive. Here we show that the causal network representing the large-scale structure of spacetime in our accelerating universe is a power-law graph with strong clustering, similar to many complex networks such as the Internet, social, or biological networks. We prove that this structural similarity is a consequence of the asymptotic equivalence between the large-scale growth dynamics of complex networks and causal networks. This equivalence suggests that unexpectedly similar laws govern the dynamics of complex networks and spacetime in the universe, with implications to network science and cosmology.

  7. Network Cosmology

    Science.gov (United States)

    Krioukov, Dmitri; Kitsak, Maksim; Sinkovits, Robert S.; Rideout, David; Meyer, David; Boguñá, Marián

    2012-01-01

    Prediction and control of the dynamics of complex networks is a central problem in network science. Structural and dynamical similarities of different real networks suggest that some universal laws might accurately describe the dynamics of these networks, albeit the nature and common origin of such laws remain elusive. Here we show that the causal network representing the large-scale structure of spacetime in our accelerating universe is a power-law graph with strong clustering, similar to many complex networks such as the Internet, social, or biological networks. We prove that this structural similarity is a consequence of the asymptotic equivalence between the large-scale growth dynamics of complex networks and causal networks. This equivalence suggests that unexpectedly similar laws govern the dynamics of complex networks and spacetime in the universe, with implications to network science and cosmology. PMID:23162688

  8. Factors Affecting Patients Undergoing Cosmetic Surgery in Bushehr, Southern Iran

    OpenAIRE

    Salehahmadi, Zeinab; Rafie, Seyyed Reza

    2012-01-01

    BACKGROUND Although, there have been extensive research on the motivations driving patient to undergo cosmetic procedures, there is still a big question mark on the persuasive factors which may lead individuals to undergo cosmetic surgery. The present study evaluated various factors affecting patients undergoing cosmetic surgery in Bushehr, Southern Iran. METHODS From 24th March 2011 to 24th March 2012, eighty-one women and 20 men who wished to be operated in Fatemeh Zahra Hospital in Bushehr...

  9. A simultaneous multi-slice selective J-resolved experiment for fully resolved scalar coupling information

    Science.gov (United States)

    Zeng, Qing; Lin, Liangjie; Chen, Jinyong; Lin, Yanqin; Barker, Peter B.; Chen, Zhong

    2017-09-01

    Proton-proton scalar coupling plays an important role in molecular structure elucidation. Many methods have been proposed for revealing scalar coupling networks involving chosen protons. However, determining all JHH values within a fully coupled network remains as a tedious process. Here, we propose a method termed as simultaneous multi-slice selective J-resolved spectroscopy (SMS-SEJRES) for simultaneously measuring JHH values out of all coupling networks in a sample within one experiment. In this work, gradient-encoded selective refocusing, PSYCHE decoupling and echo planar spectroscopic imaging (EPSI) detection module are adopted, resulting in different selective J-edited spectra extracted from different spatial positions. The proposed pulse sequence can facilitate the analysis of molecular structures. Therefore, it will interest scientists who would like to efficiently address the structural analysis of molecules.

  10. Models with Simultaneous Equations for Local Development

    Directory of Open Access Journals (Sweden)

    Ani MATEI

    2010-01-01

    Full Text Available This paper presents a model based on simultaneous equations with statistical determined parameters for describing the evolution of important issues relating to local development. The main issues considered are public and private business development environment, employment, demography, social comfort, etc. Parameter estimation with simultaneous equations model was done by procedures implemented in EViews using empirical data sets from city Braila, Romania, for the period 2000 to 2005. Applying the Durbin-Watson test, results were compared for the simultaneous equations model where the parameters were estimated by twostage least squares method.

  11. Simultaneous processing of fibril formation and cross-linking improves mechanical properties of collagen.

    Science.gov (United States)

    Yunoki, Shunji; Matsuda, Takehisa

    2008-03-01

    In vitro "simultaneous processing" was investigated in which fibril formation of collagen and cross-linking occur simultaneously in the presence of 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide (EDC) as a cross-linking reagent. Fibril formation in simultaneous processing was monitored using turbidity. The EDC in simultaneous processing increased T(1/2) (time required for half of the plateau value in turbidity) and decreased the degree of the fibril formation dose dependently. The reduced fibril formation rate (T(1/2) > 60 s) suggests the introduction of intrafibrillar cross-linking during fibril formation. The collagen gels prepared using simultaneous processing had a compressive modulus that was 6-fold higher than that using sequential processing, which is an advantage of simultaneous processing. Atomic force microscopy images acquired under water on the wet gels demonstrated that the simultaneous processing provided a unique double-network structure: intrafibrillarly cross-linked collagen fibrils among which nonfibrous collagens act as interfibrillar cross-linkages.

  12. The Dynamics of Friendships and Victimization in Adolescence : A Longitudinal Social Network Perspective

    NARCIS (Netherlands)

    Sentse, Miranda; Dijkstra, Jan Kornelis; Salmivalli, Christina; Cillessen, Antonius H. N.

    2013-01-01

    This study investigated the development of relational and physical victimization in adolescent friendship networks over time. Using longitudinal social network analysis (SIENA) it was simultaneously tested whether similarity in victimization contributed to friendship formation (selection effects)

  13. The Dynamics of Friendships and Victimization in Adolescence: A Longitudinal Social Network Perspective

    NARCIS (Netherlands)

    Sentse, M.; Dijkstra, J.K.; Salmivalli, C.; Cillessen, A.H.N.

    2013-01-01

    This study investigated the development of relational and physical victimization in adolescent friendship networks over time. Using longitudinal social network analysis (SIENA) it was simultaneously tested whether similarity in victimization contributed to friendship formation (selection effects)

  14. Detection of statistically significant network changes in complex biological networks.

    Science.gov (United States)

    Mall, Raghvendra; Cerulo, Luigi; Bensmail, Halima; Iavarone, Antonio; Ceccarelli, Michele

    2017-03-04

    Biological networks contribute effectively to unveil the complex structure of molecular interactions and to discover driver genes especially in cancer context. It can happen that due to gene mutations, as for example when cancer progresses, the gene expression network undergoes some amount of localized re-wiring. The ability to detect statistical relevant changes in the interaction patterns induced by the progression of the disease can lead to the discovery of novel relevant signatures. Several procedures have been recently proposed to detect sub-network differences in pairwise labeled weighted networks. In this paper, we propose an improvement over the state-of-the-art based on the Generalized Hamming Distance adopted for evaluating the topological difference between two networks and estimating its statistical significance. The proposed procedure exploits a more effective model selection criteria to generate p-values for statistical significance and is more efficient in terms of computational time and prediction accuracy than literature methods. Moreover, the structure of the proposed algorithm allows for a faster parallelized implementation. In the case of dense random geometric networks the proposed approach is 10-15x faster and achieves 5-10% higher AUC, Precision/Recall, and Kappa value than the state-of-the-art. We also report the application of the method to dissect the difference between the regulatory networks of IDH-mutant versus IDH-wild-type glioma cancer. In such a case our method is able to identify some recently reported master regulators as well as novel important candidates. We show that our network differencing procedure can effectively and efficiently detect statistical significant network re-wirings in different conditions. When applied to detect the main differences between the networks of IDH-mutant and IDH-wild-type glioma tumors, it correctly selects sub-networks centered on important key regulators of these two different subtypes. In

  15. Simultaneous repair of abdominal aortic aneurysm and resection of unexpected, associated abdominal malignancies.

    Science.gov (United States)

    Illuminati, Giulio; Calio', Francesco G; D'Urso, Antonio; Lorusso, Riccardo; Ceccanei, Gianluca; Vietri, Francesco

    2004-12-15

    The management of unexpected intra-abdominal malignancy, discovered at laparotomy for elective treatment of an abdominal aortic aneurysm (AAA), is controversial. It is still unclear whether both conditions should be treated simultaneously or a staged approach is to be preferred. To contribute in improving treatment guidelines, we retrospectively reviewed the records of patients undergoing laparotomy for elective AAA repair. From January 1994 to March 2003, 253 patients underwent elective, trans-peritoneal repair of an AAA. In four patients (1.6%), an associated, unexpected neoplasm was detected at abdominal exploration, consisting of one renal, one gastric, one ileal carcinoid, and one ascending colon tumor. All of them were treated at the same operation, after aortic repair and careful isolation of the prosthetic graft. The whole series' operative mortality was 3.6%. None of the patients simultaneously treated for AAA and tumor resection died in the postoperative period. No graft-related infections were observed. Simultaneous treatment of AAA and tumor did not prolong significantly the mean length of stay in the hospital, compared to standard treatment of AAA alone. Except for malignancies of organs requiring major surgical resections, simultaneous AAA repair and resection of an associated, unexpected abdominal neoplasm can be safely performed, in most of the patients, sparing the need for a second procedure. Endovascular grafting of the AAA can be a valuable tool in simplifying simultaneous treatment, or in staging the procedures with a very short delay.

  16. Hearing Preservation Among Patients Undergoing Cochlear Implantation

    Science.gov (United States)

    Van Abel, Kathryn M.; Dunn, Camille C.; Sladen, Douglas P.; Oleson, Jacob J.; Beatty, Charles W.; Neff, Brian A.; Hansen, Marlan; Gantz, Bruce J.; Driscoll, Colin L. W.

    2015-01-01

    Introduction Despite successful preservation of low-frequency hearing in patients undergoing cochlear implantation (CI) with shorter electrode lengths, there is still controversy regarding which electrodes maximize hearing preservation (HP). The thin straight electrode array (TSEA) has been suggested as a full cochlear coverage option for HP. However, very little is known regarding its HP potential. Methods A retrospective review was performed at two tertiary academic medical centers, reviewing the electronic records for 52 patients (mean, 58.2 yr; range, 11–85 yr) implanted with the Cochlear Nucleus CI422 Slim Straight (Centennial, CO, USA) electrode array, referred to herein as the thin straight electrode array or TSEA. All patients had a preoperative low-frequency pure-tone average (LFPTA) of 85 dB HL or less. Hearing thresholds were measured at initial activation (t1) and 6 months after activation (t2). HP was assessed by evaluating functional HP using a cutoff level of 85 dB HL PTA. Results At t1, 54% of the subjects had functional hearing; 33% of these subjects had an LFPTA between 71 and 85 dB HL, and 17% had an LFPTA between 56 and 70 dB HL. At t2, 47% of the patients had functional hearing, with 31% having an LFPTA between 71 and 85 dB HL. Discussion Preliminary research suggests that the TSEA has the potential to preserve functional hearing in 54% of patients at t1. However, 22% (n = 6) of the patients who had functional hearing at t1 (n = 28) lost their hearing between t1 and t2. Further studies are needed to evaluate factors that influence HP with the TSEA electrode and determine the speech perception benefits using electric and acoustic hearing over electric alone. PMID:25575373

  17. Adapting immunisation schedules for children undergoing chemotherapy.

    Science.gov (United States)

    Fernández-Prada, María; Rodríguez-Martínez, María; García-García, Rebeca; García-Corte, María Dolores; Martínez-Ortega, Carmen

    2018-02-01

    Children undergoing chemotherapy for cancer have special vaccination needs after completion of the treatment. The aim of this study was to evaluate the adaptation of post-chemotherapy vaccination schedules. An observational study was performed on a retrospective cohort that included all children aged from 0 to 14 years, who completed chemotherapy in a tertiary hospital between 2009 and 2015. Inclusion and exclusion criteria were applied. Immunisation was administered in accordance with the guidelines of the Vaccine Advisory Committee of the Spanish Association of Paediatrics. Primary Care immunisation and clinical records of the Preventive Medicine and Public Health Department were reviewed. Of the 99 children who had received chemotherapy, 51 (70.6% males) were included in the study. As regards the type of tumour, 54.9% had a solid organ tumour, and 45.1% had a haematological tumour. Post-chemotherapy immunisation was administered to 70.6%. The most common vaccines received were: diphtheria-tetanus-pertussis or diphtheria-tetanus (54.9%), meningococcus C (41.2%), and seasonal influenza (39.2%). The rate of adaptation of the immunisation schedule after chemotherapy was 9.8%. The pneumococcal conjugate vaccine against 7v or 13v was administered to 21.6% of study subjects. However, only 17.6% received polysaccharide 23v. None received vaccination against hepatitis A. No statistically significant differences were observed between adherence to immunisation schedules and type of tumour (P=.066), gender (P=.304), or age (P=.342). Post-chemotherapy immunisation of children with cancer is poor. The participation of health professionals in training programs and referral of paediatric cancer patients to Vaccine Units could improve the rate of schedule adaptation and proper immunisation of this population. Copyright © 2016 Elsevier España, S.L.U. and Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

  18. Preoperative information needs of children undergoing tonsillectomy.

    LENUS (Irish Health Repository)

    Buckley, Aoife

    2012-02-01

    AIMS AND OBJECTIVES: To identify the information needs of children undergoing tonsillectomy with reference to content of information, method of delivery, information providers and timing of information provision. BACKGROUND: Tonsillectomy can be anxiety provoking for children and preoperative preparation programmes are long recognised to reduce anxiety. However, few have been designed from the perspectives of children and to date little is known about how best to prepare children in terms of what to tell them, how to convey information to them, who can best provide information and what is the best timing for information provision. DESIGN: A qualitative descriptive study. METHOD: Data were collected from nine children (aged 6-9) using interviews supported by a write and draw technique. Data were coded and categorised into themes reflecting content, method, providers and timing of information. RESULTS: Children openly communicated their information needs especially on what to tell them to expect when facing a tonsillectomy. Their principal concerns were about operation procedures, experiencing \\'soreness\\' and discomfort postoperatively and parental presence. Mothers were viewed as best situated to provide them with information. Children were uncertain about what method of information and timing would be most helpful to them. CONCLUSION: Preoperative educational interventions need to take account of children\\'s information needs so that they are prepared for surgery in ways that are meaningful and relevant to them. Future research is needed in this area. RELEVANCE TO CLINICAL PRACTICE: Practical steps towards informing children about having a tonsillectomy include asking them what they need to know and addressing their queries accordingly. Child-centred information leaflets using a question and answer format could also be helpful to children.

  19. Simultaneous invention and the patent law

    DEFF Research Database (Denmark)

    Howells, John; Katznelson, Ron D

    inventions they often find this to challenge the idea that patent law (which rewards only the first inventor with exclusive rights) is needed to encourage invention and innovation. We review the empirical evidence alleged to show that simultaneous invention is prevalent for important inventions. In general...... is typical of important pioneer inventions in both survey evidence and alleged illustrative cases of simultaneous invention. We show this in the cases of Edison, the Wright brothers, the Selden automobile patent vis a vis Ford, Watt and the steam engine. We then point out that patent law inherently ensures...... that patent protection is not extended to near simultaneous inventions. There remain a number of simultaneous inventions discovered through interference proceedings but we find the number too small to mount a serious challenge to the general operation of patent law....

  20. Effect of stimulus width on simultaneous contrast

    Directory of Open Access Journals (Sweden)

    Veronica Shi

    2013-09-01

    Full Text Available Perceived brightness of a stimulus depends on the background against which the stimulus is set, a phenomenon known as simultaneous contrast. For instance, the same gray stimulus can look light against a black background or dark against a white background. Here we quantified the perceptual strength of simultaneous contrast as a function of stimulus width. Previous studies have reported that wider stimuli result in weaker simultaneous contrast, whereas narrower stimuli result in stronger simultaneous contrast. However, no previous research has quantified this relationship. Our results show a logarithmic relationship between stimulus width and perceived brightness. This relationship is well matched by the normalized output of a Difference-of-Gaussians (DOG filter applied to stimuli of varied widths.

  1. High fidelity wireless network evaluation for heterogeneous cognitive radio networks

    Science.gov (United States)

    Ding, Lei; Sagduyu, Yalin; Yackoski, Justin; Azimi-Sadjadi, Babak; Li, Jason; Levy, Renato; Melodia, Tammaso

    2012-06-01

    We present a high fidelity cognitive radio (CR) network emulation platform for wireless system tests, measure- ments, and validation. This versatile platform provides the configurable functionalities to control and repeat realistic physical channel effects in integrated space, air, and ground networks. We combine the advantages of scalable simulation environment with reliable hardware performance for high fidelity and repeatable evaluation of heterogeneous CR networks. This approach extends CR design only at device (software-defined-radio) or lower-level protocol (dynamic spectrum access) level to end-to-end cognitive networking, and facilitates low-cost deployment, development, and experimentation of new wireless network protocols and applications on frequency- agile programmable radios. Going beyond the channel emulator paradigm for point-to-point communications, we can support simultaneous transmissions by network-level emulation that allows realistic physical-layer inter- actions between diverse user classes, including secondary users, primary users, and adversarial jammers in CR networks. In particular, we can replay field tests in a lab environment with real radios perceiving and learning the dynamic environment thereby adapting for end-to-end goals over distributed spectrum coordination channels that replace the common control channel as a single point of failure. CR networks offer several dimensions of tunable actions including channel, power, rate, and route selection. The proposed network evaluation platform is fully programmable and can reliably evaluate the necessary cross-layer design solutions with configurable op- timization space by leveraging the hardware experiments to represent the realistic effects of physical channel, topology, mobility, and jamming on spectrum agility, situational awareness, and network resiliency. We also provide the flexibility to scale up the test environment by introducing virtual radios and establishing seamless signal

  2. Switched Internetwork: a New Networking Paradigm

    Science.gov (United States)

    Miranda, Jose E.

    Today, internetworking is undergoing significant change, driven primarily by business demands, the need to support new applications, and by ongoing advances in communications technology. As networks evolve in response to these forces of change, the challenge is to provide increased bandwidth in a scalable fashion, while also delivering class of service support for new multimedia applications. It is also important to build a flexible networking infrastructure that can accommodate the constant changes businesses undergo, and that simplifies the administration of user moves, adds and changes, while reducing the complexity associated with managing the network. Today's enterprise-wide internetworks are running mission-critical applications, and cannot be used as testbeds for trying out new technology. Consequently, it is essential that the new network maintain the highest levels of availability and reliability.

  3. Designing Synthetic Microcapsules That Undergo Biomimetic Communication and Autonomous Motion.

    Science.gov (United States)

    Yashin, Victor V; Kolmakov, German V; Shum, Henry; Balazs, Anna C

    2015-11-10

    Inspired by the collective behavior of slime molds and amoebas, we designed synthetic cell-like objects that move and self-organize in response to self-generated chemical gradients, thereby exhibiting autochemotaxis. Using computational modeling, we specifically focused on microcapsules that encompass a permeable shell and are localized on an adhesive surface in solution. Lacking any internal machinery, these spherical, fluid-filled shells might resemble the earliest protocells. Our microcapsules do, however, encase particles that can diffuse through the outer shell and into the surrounding fluid. The released particles play two important, physically realizable roles: (1) they affect the permeability of neighboring capsules and (2) they generate adhesion gradients on the underlying surface. Due to feedback mechanisms provided by the released particles, the self-generated adhesion gradients, and hydrodynamic interactions, the capsules undergo collective, self-sustained motion and even exhibit antlike tracking behavior. With the introduction of a chemically patterned stripe on the surface, a triad of capsules can be driven to pick up four-capsule cargo, transport this cargo, and drop off this payload at a designated site. We also modeled a system where the released particles give rise to a particular cycle of negative feedback loops (mimicking the "repressilator" network), which regulates the production of chemicals within the capsules and hence their release into the solution. By altering the system parameters, three capsules could be controllably driven to self-organize into a stable, close-packed triad that would either translate as a group or remain stationary. Moreover, the stationary triads could be made to switch off after assembly and thus produce minimal quantities of chemicals. Taken together, our models allow us to design a rich variety of self-propelled structures that achieve complex, cooperative behavior through fundamental physicochemical phenomena

  4. Telecommunication networks

    CERN Document Server

    Iannone, Eugenio

    2011-01-01

    Many argue that telecommunications network infrastructure is the most impressive and important technology ever developed. Analyzing the telecom market's constantly evolving trends, research directions, infrastructure, and vital needs, Telecommunication Networks responds with revolutionized engineering strategies to optimize network construction. Omnipresent in society, telecom networks integrate a wide range of technologies. These include quantum field theory for the study of optical amplifiers, software architectures for network control, abstract algebra required to design error correction co

  5. Simultaneous vs sequential adjustments in a duopoly

    Science.gov (United States)

    Ibrahim, Adyda; Karim, Sharmila; Zaibidi, Nerda Zura

    2014-12-01

    In a duopoly situation, two firms can move towards the equilibrium point either sequentially or simultaneously. In the case of equal costs and equal initial outputs, numerical results in this paper show the effect of simultaneous adjustment and sequential adjustment on the length of time it takes for a firm to reach the Cournot equilibrium, and the total profit accumulated up until reaching the equilibrium point.

  6. Structure identification and adaptive synchronization of uncertain general complex dynamical networks

    Energy Technology Data Exchange (ETDEWEB)

    Xu Yuhua, E-mail: yuhuaxu2004@163.co [College of Information Science and Technology, Donghua University, Shanghai 201620 (China) and Department of Maths, Yunyang Teacher' s College, Hubei 442000 (China); Zhou Wuneng, E-mail: wnzhou@163.co [College of Information Science and Technology, Donghua University, Shanghai 201620 (China); Fang Jian' an [College of Information Science and Technology, Donghua University, Shanghai 201620 (China); Lu Hongqian [Shandong Institute of Light Industry, Shandong Jinan 250353 (China)

    2009-12-28

    This Letter proposes an approach to identify the topological structure and unknown parameters for uncertain general complex networks simultaneously. By designing effective adaptive controllers, we achieve synchronization between two complex networks. The unknown network topological structure and system parameters of uncertain general complex dynamical networks are identified simultaneously in the process of synchronization. Several useful criteria for synchronization are given. Finally, an illustrative example is presented to demonstrate the application of the theoretical results.

  7. Obesity paradox in patients undergoing coronary intervention: A review

    OpenAIRE

    Patel, Nirav; Elsaid, Ossama; Shenoy, Abhishek; Sharma, Abhishek; McFarlane, Samy I.

    2017-01-01

    There is strong relationship exist between obesity and cardiovascular disease including coronary artery disease (CAD). However, better outcomes noted in obese patients undergoing percutaneous cardiovascular interventions for CAD, a phenomenon known as the obesity paradox. In this review, we performed extensive search for obesity paradox in obese patients undergoing percutaneous coronary intervention and discussed possible mechanism and disparities in different race and sex.

  8. Factors that affect the likelihood of undergoing cosmetic surgery.

    Science.gov (United States)

    Brown, Amy; Furnham, Adrian; Glanville, Louise; Swami, Viren

    2007-01-01

    With the rise in popularity of plastic surgery, it is useful to consider those factors that may increase the likelihood of undergoing cosmetic surgery in a nonpatient population. A study was conducted to determine those factors that might motivate a nonclinical, nonpatient population to undergo cosmetic surgery. A sample of 119 women and 89 men, ages 18 to 59, was recruited from public spaces and asked to complete a questionnaire measuring how likely they were to consider undergoing the most common cosmetic procedures. Women reported greater likelihood of undergoing cosmetic surgery than men, older men expressed less desire to undergo cosmetic surgery than younger men, and lower self-ratings of physical attractiveness predicted higher likelihood of undergoing cosmetic surgery. The vicarious experience of cosmetic surgery (via family and friends) increased the likelihood of undergoing cosmetic surgery for women, but not for men. Media exposure did not influence likelihood for either sex. Factors that affect the likelihood of undergoing cosmetic surgery vary with procedure; thus it would be valuable for future studies to use a scale that measures responses separately for different procedures. Lower self-ratings of physical attractiveness lead to consideration of cosmetic surgery; future studies may explore satisfaction levels of those who have undergone surgery.

  9. Interconnected networks

    CERN Document Server

    2016-01-01

    This volume provides an introduction to and overview of the emerging field of interconnected networks which include multi layer or multiplex networks, as well as networks of networks. Such networks present structural and dynamical features quite different from those observed in isolated networks. The presence of links between different networks or layers of a network typically alters the way such interconnected networks behave – understanding the role of interconnecting links is therefore a crucial step towards a more accurate description of real-world systems. While examples of such dissimilar properties are becoming more abundant – for example regarding diffusion, robustness and competition – the root of such differences remains to be elucidated. Each chapter in this topical collection is self-contained and can be read on its own, thus making it also suitable as reference for experienced researchers wishing to focus on a particular topic.

  10. Differential Simultaneous Liver and Kidney Transplant Benefit Based on Severity of Liver Damage at the Time of Transplantation

    Science.gov (United States)

    Habib, Shahid; Khan, Khalid; Hsu, Chiu-Hsieh; Meister, Edward; Rana, Abbas; Boyer, Thomas

    2017-01-01

    Background We evaluated the concept of whether liver failure patients with a superimposed kidney injury receiving a simultaneous liver and kidney transplant (SLKT) have similar outcomes compared to patients with liver failure without a kidney injury receiving a liver transplantation (LT) alone. Methods Using data from the United Network of Organ Sharing (UNOS) database, patients were divided into five groups based on pre-transplant model for end-stage liver disease (MELD) scores and categorized as not having (serum creatinine (sCr) ≤ 1.5 mg/dL) or having (sCr > 1.5 mg/dL) renal dysfunction. Of 30,958 patients undergoing LT, 14,679 (47.5%) had renal dysfunction, and of those, 5,084 (16.4%) had dialysis. Results Survival in those (liver failure with renal dysfunction) receiving SLKT was significantly worse (P liver failure only). The highest mortality rate observed was 21% in the 36+ MELD group with renal dysfunction with or without SLKT. In high MELD recipients (MELD > 30) with renal dysfunction, presence of renal dysfunction affects the outcome and SLKT does not improve survival. In low MELD recipients (16 - 20), presence of renal dysfunction at the time of transplantation does affect post-transplant survival, but survival is improved with SLKT. Conclusions SLKT improved 1-year survival only in low MELD (16 - 20) recipients but not in other groups. Performance of SLKT should be limited to patients where a benefit in survival and post-transplant outcomes can be demonstrated. PMID:28496531

  11. Complex quantum network geometries: Evolution and phase transitions

    Science.gov (United States)

    Bianconi, Ginestra; Rahmede, Christoph; Wu, Zhihao

    2015-08-01

    Networks are topological and geometric structures used to describe systems as different as the Internet, the brain, or the quantum structure of space-time. Here we define complex quantum network geometries, describing the underlying structure of growing simplicial 2-complexes, i.e., simplicial complexes formed by triangles. These networks are geometric networks with energies of the links that grow according to a nonequilibrium dynamics. The evolution in time of the geometric networks is a classical evolution describing a given path of a path integral defining the evolution of quantum network states. The quantum network states are characterized by quantum occupation numbers that can be mapped, respectively, to the nodes, links, and triangles incident to each link of the network. We call the geometric networks describing the evolution of quantum network states the quantum geometric networks. The quantum geometric networks have many properties common to complex networks, including small-world property, high clustering coefficient, high modularity, and scale-free degree distribution. Moreover, they can be distinguished between the Fermi-Dirac network and the Bose-Einstein network obeying, respectively, the Fermi-Dirac and Bose-Einstein statistics. We show that these networks can undergo structural phase transitions where the geometrical properties of the networks change drastically. Finally, we comment on the relation between quantum complex network geometries, spin networks, and triangulations.

  12. Networks and transaction costs

    DEFF Research Database (Denmark)

    Henning, Christian H.C.A.; Henningsen, Geraldine; Henningsen, Arne

    -multiple output stochastic Ray production function to generate relative shadow prices of three inputs and two outputs traded by farms. At a second stage a structural equation system is derived from the first order conditions of farm’s profit maximization to estimate simultaneously the of commodity specific...... transaction cost functions for all traded farm inputs and outputs. Estimation results based on a sample of 315 Polish farms imply a significant influence of social network structures on farm’s transaction costs. Moreover, estimated transaction costs correspond to a reasonable amount of farm specific shadow...... prices....

  13. INTESTINAL MALROTATION IN PATIENTS UNDERGOING BARIATRIC SURGERY.

    Science.gov (United States)

    Vidal, Eduardo Arevalo; Rendon, Francisco Abarca; Zambrano, Trino Andrade; García, Yudoco Andrade; Viteri, Mario Ferrin; Campos, Josemberg Marins; Ramos, Manoela Galvão; Ramos, Almino Cardoso

    Intestinal malrotation is a rare congenital anomaly. In adults is very difficult to recognize due to the lack of symptoms. Diagnosis is usually incidental during surgical procedures or at autopsy. To review the occurrence and recognition of uneventful intestinal malrotation discovered during regular cases of bariatric surgeries. Were retrospectively reviewed the medical registry of 20,000 cases undergoing bariatric surgery, from January 2002 to January 2016, looking for the occurrence of intestinal malrotation and consequences in the intraoperative technique and immediate evolution of the patients. Five cases (0,025%) of intestinal malrotation were found. All of them were males, aging 45, 49, 37,52 and 39 years; BMI 35, 42, 49, 47 and 52 kg/m2, all of them with a past medical history of morbid obesity. The patient with BMI 35 kg/m2 suffered from type 2 diabetes also. All procedures were completed by laparoscopic approach, with no conversions. In one patient was not possible to move the jejunum to the upper abdomen in order to establish the gastrojejunostomy and a sleeve gastrectomy was performed. In another patient was not possible to fully recognize the anatomy due to bowel adhesions and a single anastomosis gastric bypass was preferred. No leaks or bleeding were identified. There were no perioperative complications. All patients were discharged 72 h after the procedure and no immediate 30-day complications were reported. Patients with malrotation can successfully undergo laparoscopic bariatric surgery. May be necessary changes in the surgical original strategy regarding the malrotation. Surgeons must check full abdominal anatomical condition prior to start the division of the stomach. Má-rotação intestinal é rara anomalia congênita em adultos de difícil reconhecimento devido à falta de sintomas. O diagnóstico é feito geralmente incidentalmente durante procedimentos cirúrgicos ou durante autópsia. Verificar a ocorrência e reconhecimento não eventual

  14. Network maintenance

    CERN Multimedia

    IT Department

    2009-01-01

    A site wide network maintenance has been scheduled for Saturday 28 February. Most of the network devices of the General Purpose network will be upgraded to a newer software version, in order to improve our network monitoring capabilities. This will result in a series of short (2-5 minutes) random interruptions everywhere on the CERN sites along this day. This upgrade will not affect: the Computer centre itself, building 613, the Technical Network and the LHC experiments dedicated networks at the pits. Should you need more details on this intervention, please contact Netops by phone 74927 or email mailto:Netops@cern.ch. IT/CS Group

  15. Network maintenance

    CERN Multimedia

    GS Department

    2009-01-01

    A site-wide network maintenance operation has been scheduled for Saturday 28 February. Most of the network devices of the general purpose network will be upgraded to a newer software version, in order to improve our network monitoring capabilities. This will result in a series of short (2-5 minutes) random interruptions everywhere on the CERN sites throughout the day. This upgrade will not affect the Computer Centre itself, Building 613, the Technical Network and the LHC experiments, dedicated networks at the pits. For further details of this intervention, please contact Netops by phone 74927 or e-mail mailto:Netops@cern.ch. IT/CS Group

  16. Stochastic Recursive Algorithms for Optimization Simultaneous Perturbation Methods

    CERN Document Server

    Bhatnagar, S; Prashanth, L A

    2013-01-01

    Stochastic Recursive Algorithms for Optimization presents algorithms for constrained and unconstrained optimization and for reinforcement learning. Efficient perturbation approaches form a thread unifying all the algorithms considered. Simultaneous perturbation stochastic approximation and smooth fractional estimators for gradient- and Hessian-based methods are presented. These algorithms: • are easily implemented; • do not require an explicit system model; and • work with real or simulated data. Chapters on their application in service systems, vehicular traffic control and communications networks illustrate this point. The book is self-contained with necessary mathematical results placed in an appendix. The text provides easy-to-use, off-the-shelf algorithms that are given detailed mathematical treatment so the material presented will be of significant interest to practitioners, academic researchers and graduate students alike. The breadth of applications makes the book appropriate for reader from sim...

  17. A system with coupled processors and simultaneous arrivals

    Science.gov (United States)

    Dimitriou, Ioannis

    2017-07-01

    In this work, motivated by emerging applications in wireless concurrent access networks and manufacturing, we analyze for the first time a system of two coupled queues accepting three flows of jobs, say a central and two background. A job from the central flow is split in two sub-jobs, which are placed simultaneously at each queue, while each background job joins a dedicated queue. We also assume that the departure rate at each queue, depends on the presence/absence of jobs in the other queue. We investigate stability conditions and prove that the generating function of the joint queue length distribution is obtained as a solution of a Dirichlet boundary value problem. A simple numerical example is also presented.

  18. Network Ambivalence

    Directory of Open Access Journals (Sweden)

    Patrick Jagoda

    2015-08-01

    Full Text Available The language of networks now describes everything from the Internet to the economy to terrorist organizations. In distinction to a common view of networks as a universal, originary, or necessary form that promises to explain everything from neural structures to online traffic, this essay emphasizes the contingency of the network imaginary. Network form, in its role as our current cultural dominant, makes scarcely imaginable the possibility of an alternative or an outside uninflected by networks. If so many things and relationships are figured as networks, however, then what is not a network? If a network points towards particular logics and qualities of relation in our historical present, what others might we envision in the future? In  many ways, these questions are unanswerable from within the contemporary moment. Instead of seeking an avant-garde approach (to move beyond networks or opting out of networks (in some cases, to recover elements of pre-networked existence, this essay proposes a third orientation: one of ambivalence that operates as a mode of extreme presence. I propose the concept of "network aesthetics," which can be tracked across artistic media and cultural forms, as a model, style, and pedagogy for approaching interconnection in the twenty-first century. The following essay is excerpted from Network Ambivalence (Forthcoming from University of Chicago Press. 

  19. Paper Skin Multisensory Platform for Simultaneous Environmental Monitoring

    KAUST Repository

    Nassar, Joanna M.

    2016-02-19

    Human skin and hair can simultaneously feel pressure, temperature, humidity, strain, and flow—great inspirations for applications such as artificial skins for burn and acid victims, robotics, and vehicular technology. Previous efforts in this direction use sophisticated materials or processes. Chemically functionalized, inkjet printed or vacuum-technology-processed papers albeit cheap have shown limited functionalities. Thus, performance and/or functionalities per cost have been limited. Here, a scalable “garage” fabrication approach is shown using off-the-shelf inexpensive household elements such as aluminum foil, scotch tapes, sticky-notes, napkins, and sponges to build “paper skin” with simultaneous real-time sensing capability of pressure, temperature, humidity, proximity, pH, and flow. Enabling the basic principles of porosity, adsorption, and dimensions of these materials, a fully functioning distributed sensor network platform is reported, which, for the first time, can sense the vitals of its carrier (body temperature, blood pressure, heart rate, and skin hydration) and the surrounding environment.

  20. Alterations in audiovisual simultaneity perception in amblyopia.

    Science.gov (United States)

    Richards, Michael D; Goltz, Herbert C; Wong, Agnes M F

    2017-01-01

    Amblyopia is a developmental visual impairment that is increasingly recognized to affect higher-level perceptual and multisensory processes. To further investigate the audiovisual (AV) perceptual impairments associated with this condition, we characterized the temporal interval in which asynchronous auditory and visual stimuli are perceived as simultaneous 50% of the time (i.e., the AV simultaneity window). Adults with unilateral amblyopia (n = 17) and visually normal controls (n = 17) judged the simultaneity of a flash and a click presented with both eyes viewing. The signal onset asynchrony (SOA) varied from 0 ms to 450 ms for auditory-lead and visual-lead conditions. A subset of participants with amblyopia (n = 6) was tested monocularly. Compared to the control group, the auditory-lead side of the AV simultaneity window was widened by 48 ms (36%; p = 0.002), whereas that of the visual-lead side was widened by 86 ms (37%; p = 0.02). The overall mean window width was 500 ms, compared to 366 ms among controls (37% wider; p = 0.002). Among participants with amblyopia, the simultaneity window parameters were unchanged by viewing condition, but subgroup analysis revealed differential effects on the parameters by amblyopia severity, etiology, and foveal suppression status. Possible mechanisms to explain these findings include visual temporal uncertainty, interocular perceptual latency asymmetry, and disruption of normal developmental tuning of sensitivity to audiovisual asynchrony.

  1. Bilateral Simultaneous Tubal Ectopic Pregnancy: A Case Report, Review of Literature and a Proposed Management Algorithm.

    Science.gov (United States)

    Jena, Saubhagya Kumar; Singh, Sweta; Nayak, Monalisha; Das, Leena; Senapati, Swagatika

    2016-03-01

    Bilateral simultaneous Tubal Ectopic Pregnancy (BTP) is the rarest form of ectopic pregnancy. The incidence is higher in women undergoing assisted reproductive techniques or ovulation induction. The clinical presentation is unpredictable and there are no unique features to distinguish it from unilateral ectopic pregnancy. BTP continues to be a clinician's dilemma as pre-operative diagnosis is difficult and is commonly made during surgery. Treatment options are varied depending on site of ectopic pregnancy, extent of tubal damage and requirement of future fertility. We report a case of BTP which was diagnosed during surgery and propose an algorithm for management of such patients.

  2. Network neuroscience.

    Science.gov (United States)

    Bassett, Danielle S; Sporns, Olaf

    2017-02-23

    Despite substantial recent progress, our understanding of the principles and mechanisms underlying complex brain function and cognition remains incomplete. Network neuroscience proposes to tackle these enduring challenges. Approaching brain structure and function from an explicitly integrative perspective, network neuroscience pursues new ways to map, record, analyze and model the elements and interactions of neurobiological systems. Two parallel trends drive the approach: the availability of new empirical tools to create comprehensive maps and record dynamic patterns among molecules, neurons, brain areas and social systems; and the theoretical framework and computational tools of modern network science. The convergence of empirical and computational advances opens new frontiers of scientific inquiry, including network dynamics, manipulation and control of brain networks, and integration of network processes across spatiotemporal domains. We review emerging trends in network neuroscience and attempt to chart a path toward a better understanding of the brain as a multiscale networked system.

  3. Organizational Networks

    DEFF Research Database (Denmark)

    Grande, Bård; Sørensen, Ole Henning

    1998-01-01

    The paper focuses on the concept of organizational networks. Four different uses of the concept of organizational network are identified and critically discussed. Special focus is placed on how information and communication technologies as communication mediators and cognitive pictures influence...

  4. Network workshop

    DEFF Research Database (Denmark)

    Bruun, Jesper; Evans, Robert Harry

    2014-01-01

    This paper describes the background for, realisation of and author reflections on a network workshop held at ESERA2013. As a new research area in science education, networks offer a unique opportunity to visualise and find patterns and relationships in complicated social or academic network data...... research community. With this workshop, participants were offered a way into network science based on authentic educational research data. The workshop was constructed as an inquiry lesson with emphasis on user autonomy. Learning activities had participants choose to work with one of two cases of networks...... network methodology in one’s research might supersede the perceived benefits of doing so. As a response to that problem, we argue that workshops can act as a road towards meaningful engagement with networks and highlight that network methodology promises new ways of interpreting data to answer questions...

  5. Evolution of cooperation in multiplex networks.

    Science.gov (United States)

    Gómez-Gardeñes, Jesús; Reinares, Irene; Arenas, Alex; Floría, Luis Mario

    2012-01-01

    We study evolutionary game dynamics on structured populations in which individuals take part in several layers of networks of interactions simultaneously. This multiplex of interdependent networks accounts for the different kind of social ties each individual has. By coupling the evolutionary dynamics of a Prisoner's Dilemma game in each of the networks, we show that the resilience of cooperative behaviors for extremely large values of the temptation to defect is enhanced by the multiplex structure. Furthermore, this resilience is intrinsically related to a non-trivial organization of cooperation across the network layers, thus providing a new way out for cooperation to survive in structured populations.

  6. Medical Crowdfunding for Patients Undergoing Orthopedic Surgery.

    Science.gov (United States)

    Durand, Wesley M; Johnson, Joseph R; Eltorai, Adam E M; Daniels, Alan H

    2018-01-01

    Crowdfunding for medical expenses is growing in popularity. Through several websites, patients create public campaign profiles to which donors can contribute. Research on medical crowdfunding is limited, and there have been no studies of crowdfunding in orthopedics. Active medical crowdfunding campaigns for orthopedic trauma, total joint arthroplasty, and spine surgery were queried from a crowdfunding website. The characteristics and outcomes of crowdfunding campaigns were abstracted and analyzed. For this study, 444 campaigns were analyzed, raising a total of $1,443,528. Among the campaigns that received a donation, mean amount raised was $4414 (SE, $611). Multivariate analysis showed that campaigns with unspecified location (odds ratio, 0.26; P=.0008 vs West) and those for total joint arthroplasty (odds ratio, 0.35; P=.0003 vs trauma) had significantly lower odds of receipt of any donation. Description length was associated with higher odds of donation receipt (odds ratio, 1.13 per +100 characters; P<.0001). Among campaigns that received any donation, those with Southern location (-65.5%, P<.0001), international location (-68.5%, P=.0028), and unspecified location (-63.5%, P=.0039) raised lower amounts compared with campaigns in the West. Goal amount was associated with higher amount raised (+3.2% per +$1000, P<.0001). Resources obtained through crowdfunding may be disproportionately available to patients with specific diagnoses, those from specific regions, those who are able to craft a lengthy descriptive narrative, and those with access to robust digital social networks. Clinicians are likely to see a greater proportion of patients turning to crowdfunding as it grows in popularity. Patients may ask physicians for information about crowdfunding or request testimonials to support campaigns. Surgeons should consider their response to such requests individually. These findings shed light on the dynamics of medical crowdfunding and support robust personal and

  7. Impact of simultaneous pancreas-kidney transplantation: patients’ perspectives

    Science.gov (United States)

    Isla Pera, P; Moncho Vasallo, J; Guasch Andreu, O; Ricart Brulles, MJ; Torras Rabasa, A

    2012-01-01

    Background: Few qualitative studies of simultaneous pancreas-kidney transplantation (SPK Tx) have been published. The aims of this study were to explore from the perspective of patients, the experience of living with diabetes mellitus type 1 (T1DM), suffering from complications, and undergoing SPK Tx with good outcome; and to determine the impact of SPK Tx on patients and their social and cultural environment. Methods: We performed a focused ethnographic study. Twenty patients were interviewed. Data were analyzed using content analysis and constant comparison following the method proposed by Miles and Huberman. Results: A functioning SPK Tx allowed renal replacement therapy and insulin to be discontinued. To describe their new situation, patients used words and phrases such as “miracle”, “being reborn” or “coming back to life”. Although the complications of T1DM, its surgery and treatment, and associated psychological problems did not disappear after SPK Tx, these were minimized when compared with the pretransplantation situation. Conclusion: For patients, SPK Tx represents a recovery of their health and autonomy despite remaining problems associated with the complications of T1DM and SPK Tx. The understanding of patients’ existential framework and their experience of disease are key factors for planning new intervention and improvement strategies. PMID:22936846

  8. Thermotolerant fermenting yeasts for simultaneous saccharification fermentation of lignocellulosic biomass

    Directory of Open Access Journals (Sweden)

    Jairam Choudhary

    2016-05-01

    Full Text Available Lignocellulosic biomass is the most abundant renewable source of energy that has been widely explored as second-generation biofuel feedstock. Despite more than four decades of research, the process of ethanol production from lignocellulosic (LC biomass remains economically unfeasible. This is due to the high cost of enzymes, end-product inhibition of enzymes, and the need for cost-intensive inputs associated with a separate hydrolysis and fermentation (SHF process. Thermotolerant yeast strains that can undergo fermentation at temperatures above 40°C are suitable alternatives for developing the simultaneous saccharification and fermentation (SSF process to overcome the limitations of SHF. This review describes the various approaches to screen and develop thermotolerant yeasts via genetic and metabolic engineering. The advantages and limitations of SSF at high temperatures are also discussed. A critical insight into the effect of high temperatures on yeast morphology and physiology is also included. This can improve our understanding of the development of thermotolerant yeast amenable to the SSF process to make LC ethanol production commercially viable.

  9. THE GOODNESS OF SIMULTANEOUS FITS IN ISIS

    Directory of Open Access Journals (Sweden)

    Matthias Kühnel

    2016-02-01

    Full Text Available In a previous work, we introduced a tool for analyzing multiple datasets simultaneously, which has been implemented into ISIS. This tool was used to fit many spectra of X-ray binaries. However, the large number of degrees of freedom and individual datasets raise an issue about a good measure for a simultaneous fit quality. We present three ways to check the goodness of these fits: we investigate the goodness of each fit in all datasets, we define a combined goodness exploiting the logical structure of a simultaneous fit, and we stack the fit residuals of all datasets to detect weak features. These tools are applied to all RXTE-spectra from GRO 1008−57, revealing calibration features that are not detected significantly in any single spectrum. Stacking the residuals from the best-fit model for the Vela X-1 and XTE J1859+083 data evidences fluorescent emission lines that would have gone undetected otherwise.

  10. Social Networks

    OpenAIRE

    Martí, Joan; Zenou, Yves

    2009-01-01

    We survey the literature on social networks by putting together the economics, sociological and physics/applied mathematics approaches, showing their similarities and differences. We expose, in particular, the two main ways of modeling network formation. While the physics/applied mathematics approach is capable of reproducing most observed networks, it does not explain why they emerge. On the contrary, the economics approach is very precise in explaining why networks emerge but does a poor jo...

  11. Factors affecting patients undergoing cosmetic surgery in bushehr, southern iran.

    Science.gov (United States)

    Salehahmadi, Zeinab; Rafie, Seyyed Reza

    2012-07-01

    Although, there have been extensive research on the motivations driving patient to undergo cosmetic procedures, there is still a big question mark on the persuasive factors which may lead individuals to undergo cosmetic surgery. The present study evaluated various factors affecting patients undergoing cosmetic surgery in Bushehr, Southern Iran. From 24th March 2011 to 24th March 2012, eighty-one women and 20 men who wished to be operated in Fatemeh Zahra Hospital in Bushehr, Southern Iran and Pars Clinic, Iran were enrolled by a simple random sampling method. They all completed a questionnaire to consider reasons for cosmetic procedures. The collected data were statistically analyzed. Demographical, sociological and psychological factors such as age, gender, educational level, marital status, media, perceived risks, output quality, depression and self-improvement were determined as factors affecting tendency of individuals to undergo cosmetic surgery in this region. Trend to undergo cosmetic surgery was more prevalent in educational below bachelor degree, married subjects, women population of 30-45 years age group. Education level, age, marital status and gender were respectively the influential factors in deciding to undergo cosmetic surgery. Among the socio-psychological factors, self-improvement, finding a better job opportunity, rivalry, media, health status as well as depression were the most persuasive factors to encourage people to undergo cosmetic surgery too. Cost risk was not important for our samples in decision making to undergo cosmetic surgery. We need to fully understand the way in which the combination of demographic, social and psychological factors influence decision-making to undergo cosmetic surgery.

  12. 78 FR 35272 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-06-12

    ... limited to preconception health; autism spectrum disorders (ASDs) and other developmental disabilities... knowledge, awareness, screening, and prevention behaviors and could simultaneously work to reduce stigma...

  13. Network Coding

    Indian Academy of Sciences (India)

    Network coding is a technique to increase the amount of information °ow in a network by mak- ing the key observation that information °ow is fundamentally different from commodity °ow. Whereas, under traditional methods of opera- tion of data networks, intermediate nodes are restricted to simply forwarding their incoming.

  14. Simultaneous wireless electrophysiological and neurochemical monitoring

    Science.gov (United States)

    Murari, Kartikeya; Mollazadeh, Mohsen; Thakor, Nitish; Cauwenberghs, Gert

    2008-08-01

    Information processing and propagation in the central nervous system is mostly electrical in nature. At synapses, electrical signals cause the release of neurotransmitters like dopamine, glutamate etc., that are sensed by post-synaptic neurons resulting in signal propagation or inhibition. It can be very informative to monitor electrical and neurochemical signals simultaneously to understand the mechanisms underlying normal or abnormal brain function. We present an integrated system for the simultaneous wireless acquisition of neurophysiological and neurochemical activity. Applications of the system to neuroscience include monitoring EEG and glutamate in rat somatosensory cortex following global ischemia.

  15. Heart morphogenesis gene regulatory networks revealed by temporal expression analysis.

    Science.gov (United States)

    Hill, Jonathon T; Demarest, Bradley; Gorsi, Bushra; Smith, Megan; Yost, H Joseph

    2017-10-01

    During embryogenesis the heart forms as a linear tube that then undergoes multiple simultaneous morphogenetic events to obtain its mature shape. To understand the gene regulatory networks (GRNs) driving this phase of heart development, during which many congenital heart disease malformations likely arise, we conducted an RNA-seq timecourse in zebrafish from 30 hpf to 72 hpf and identified 5861 genes with altered expression. We clustered the genes by temporal expression pattern, identified transcription factor binding motifs enriched in each cluster, and generated a model GRN for the major gene batteries in heart morphogenesis. This approach predicted hundreds of regulatory interactions and found batteries enriched in specific cell and tissue types, indicating that the approach can be used to narrow the search for novel genetic markers and regulatory interactions. Subsequent analyses confirmed the GRN using two mutants, Tbx5 and nkx2-5, and identified sets of duplicated zebrafish genes that do not show temporal subfunctionalization. This dataset provides an essential resource for future studies on the genetic/epigenetic pathways implicated in congenital heart defects and the mechanisms of cardiac transcriptional regulation. © 2017. Published by The Company of Biologists Ltd.

  16. Simultaneous/Incidental cholecystectomy during gastric/esophageal resection: systematic analysis of risks and benefits.

    Science.gov (United States)

    Gillen, Sonja; Michalski, Christoph W; Schuster, Tibor; Feith, Marcus; Friess, Helmut; Kleeff, Jörg

    2010-05-01

    After esophageal/gastric resection with resulting truncal vagotomy, the incidence of gallstone formation seems to increase. The clinical relevance of gallstones and the role of simultaneous/incidental cholecystectomy in this setting are controversially discussed. Systematic analysis has been performed for retrospective/prospective studies on the incidence/symptoms of gallstone formation after esophageal/gastric resection. Pooled estimates of the incidence of cholecystectomies were calculated by random effect models. Risk analyses of simultaneous, acute postoperative cholecystectomy and long-term cholecystectomy were performed. Sixteen studies on gallstone formation after upper gastrointestinal (GI) surgery (3,735 patients) reported increased incidences of 5-60% with a pooled estimate of 17.5% (95% confidence interval (CI), 14.1-21.2%; inconsistency statistic (I (2)) = 86%) compared with 4-12% in the control population. In 113 of 3,011 patients (12 studies), late cholecystectomies were performed for symptomatic cholecystolithiasis, corresponding to an estimated overall proportion of 4.7% (95% CI, 2.1-8.2%; I (2) = 92%). In 1.2% (95% CI, >0-3.7%; I (2) = 93%) of patients undergoing upper GI surgery, a cholecystectomy was performed because of acute postoperative biliary problems (4 studies, 8,748 patients). Simultaneous cholecystectomy had a higher morbidity of 0.95% (95% CI, 0.54-1.49%; I (2) = 28%) compared with the calculated additional morbidity of early and late cholecystectomy of 0.45%. Approximately 6% of patients undergoing upper GI surgery are expected to require cholecystectomy during follow-up. Because late cholecystectomies can be performed safely and because the additional calculated morbidity for these operations is lower than the morbidity for simultaneous cholecystectomy, it cannot generally be recommended to remove a normal acalculous gallbladder during upper GI surgery.

  17. Changes in Social Networks of Women and Men Following Divorce.

    Science.gov (United States)

    Milardo, Robert M.

    1987-01-01

    Analyzes the character and consequences of changes in the social networks of spouses following separation and divorce. For men, traditions encourage the development of personal friendships while simultaneously encouraging independence. Women, who accept responsibility for "kinkeeping" during and after marriage, simultaneously discouraging bonds…

  18. Technical Network

    CERN Multimedia

    2007-01-01

    In order to optimise the management of the Technical Network (TN), to facilitate understanding of the purpose of devices connected to the TN and to improve security incident handling, the Technical Network Administrators and the CNIC WG have asked IT/CS to verify the "description" and "tag" fields of devices connected to the TN. Therefore, persons responsible for systems connected to the TN will receive e-mails from IT/CS asking them to add the corresponding information in the network database at "network-cern-ch". Thank you very much for your cooperation. The Technical Network Administrators & the CNIC WG

  19. Network science

    CERN Document Server

    Barabasi, Albert-Laszlo

    2016-01-01

    Networks are everywhere, from the Internet, to social networks, and the genetic networks that determine our biological existence. Illustrated throughout in full colour, this pioneering textbook, spanning a wide range of topics from physics to computer science, engineering, economics and the social sciences, introduces network science to an interdisciplinary audience. From the origins of the six degrees of separation to explaining why networks are robust to random failures, the author explores how viruses like Ebola and H1N1 spread, and why it is that our friends have more friends than we do. Using numerous real-world examples, this innovatively designed text includes clear delineation between undergraduate and graduate level material. The mathematical formulas and derivations are included within Advanced Topics sections, enabling use at a range of levels. Extensive online resources, including films and software for network analysis, make this a multifaceted companion for anyone with an interest in network sci...

  20. Vulnerability of network of networks

    Science.gov (United States)

    Havlin, S.; Kenett, D. Y.; Bashan, A.; Gao, J.; Stanley, H. E.

    2014-10-01

    Our dependence on networks - be they infrastructure, economic, social or others - leaves us prone to crises caused by the vulnerabilities of these networks. There is a great need to develop new methods to protect infrastructure networks and prevent cascade of failures (especially in cases of coupled networks). Terrorist attacks on transportation networks have traumatized modern societies. With a single blast, it has become possible to paralyze airline traffic, electric power supply, ground transportation or Internet communication. How, and at which cost can one restructure the network such that it will become more robust against malicious attacks? The gradual increase in attacks on the networks society depends on - Internet, mobile phone, transportation, air travel, banking, etc. - emphasize the need to develop new strategies to protect and defend these crucial networks of communication and infrastructure networks. One example is the threat of liquid explosives a few years ago, which completely shut down air travel for days, and has created extreme changes in regulations. Such threats and dangers warrant the need for new tools and strategies to defend critical infrastructure. In this paper we review recent advances in the theoretical understanding of the vulnerabilities of interdependent networks with and without spatial embedding, attack strategies and their affect on such networks of networks as well as recently developed strategies to optimize and repair failures caused by such attacks.

  1. Micronutrient deficiency in obese subjects undergoing low calorie diet

    National Research Council Canada - National Science Library

    Damms-Machado, Antje; Weser, Gesine; Bischoff, Stephan C

    2012-01-01

    .... Furthermore, we determined the micronutrient status in obese subjects undergoing a standardized DRI-covering low-calorie formula diet to analyze if the DRI meet the micronutrient requirements of obese individuals...

  2. Experiense with remineraling means in patients undergoing orthodontic treatment

    Directory of Open Access Journals (Sweden)

    Stepanova Ye.A.

    2011-03-01

    Full Text Available In patients undergoing orthodontic treatment using bracket-technology a high risk of caries development. The algorithm of preventive interventions for the prevention of hair demineralization of enamel of the teeth

  3. Do patients fear undergoing general anesthesia for oral surgery?

    Science.gov (United States)

    Elmore, Jasmine R; Priest, James H; Laskin, Daniel M

    2014-01-01

    Many patients undergoing major surgery have more fear of the general anesthesia than the procedure. This appears to be reversed with oral surgery. Therefore, patients need to be as well informed about this aspect as the surgical operation.

  4. Coagulation profile in patients undergoing video-assisted thoracoscopic lobectomy

    DEFF Research Database (Denmark)

    Christensen, Thomas Decker; Vad, Henrik; Pedersen, Søren

    2017-01-01

    Background: Knowledge about the impact of Low-Molecular-Weight Heparin (LMWH) on the coagulation system in patients undergoing minimal invasive lung cancer surgery is sparse. The aim of this study was to assess the effect of LMWH on the coagulation system in patients undergoing Video......-Assisted Thoracoscopic Surgery (VATS) lobectomy for primary lung cancer. Methods: Sixty-three patients diagnosed with primary lung cancer undergoing VATS lobectomy were randomized to either subcutaneous injection with dalteparin (Fragmin®) 5000 IE once daily or no intervention. Coagulation was assessed pre-, peri......-, and the first two days postoperatively by standard coagulation blood test, thromboelastometry (ROTEM®) and thrombin generation. Results: Patients undergoing potential curative surgery for lung cancer were not hypercoagulable preoperatively. There was no statistically significant difference in the majority...

  5. Stressors and anxiety in patients undergoing coronary artery bypass surgery

    National Research Council Canada - National Science Library

    Gallagher, Robyn; McKinley, Sharon

    2007-01-01

    Patients undergoing coronary artery bypass surgery who have increased anxiety levels have poorer outcomes than patients with lower levels, yet few studies have identified the concerns associated with this anxiety...

  6. 77 FR 69484 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-11-19

    ... HUMAN SERVICES Centers for Disease Control and Prevention Agency Forms Undergoing Paperwork Reduction...--Scientific Education and Professional Development Program Office (SEPDPO), Office of Surveillance... public health problems rapidly ensures cost-effective health care and enhances health promotion and...

  7. Simultaneous Multi-Element Electrothermal Atomic Absorption ...

    African Journals Online (AJOL)

    In the experiments simultaneous determination of 18 elements was performed in the mixed solutions at the mg L–1 to μg L–1 level, within 4–4.5 orders of magnitude linear concentration range. About 1–2 min was needed for the measurement and calculation. Limits of detection (LOD) for individual elements were 1.5–2 ...

  8. Improved derivatization protocol for simultaneous determination of ...

    African Journals Online (AJOL)

    sensitivity and tailing in gas chromatographic analysis (Ding and Tzing, 1998 ... simultaneously. METHODS. Chemicals and standards. The derivatizing agent, HFBA, was of analytical grade, pur- chased from Sigma-Aldrich South Africa. The solvents .... analytes with different chemical structure and polarities were extracted ...

  9. Estimating carrying capacity with simultaneous nutritional constraints.

    Science.gov (United States)

    Thomas A. Hanley; James J. Rogers

    1989-01-01

    A new procedure is presented for estimating carrying capacity (the number of animals of a given species that can be supported per unit area of habitat) on the basis of two simultaneous nutritional constraints. It requires specifying the quantity (bio-mass) and quality (chemical composition or digestibility) of available food and the nutritional requirements of the...

  10. influence of simultaneous infestations of prostephanus truncatus ...

    African Journals Online (AJOL)

    significant differences in the percentage change of adult insect numbers between single and simultaneous infestations at P< 0.01. Further, the grain ... complete development over a wide range of temperatures, 270C to 320C and between ... Aging, sexing and conditioning P. truncatus and S. zeamais. Adults were removed ...

  11. Simultaneous Spectrophotometric Determination of Valsartan and ...

    African Journals Online (AJOL)

    Purpose: To develop a direct, simple and extraction-free spectrophotometric method for the simultaneous estimation of valsartan and ezetimibe in pharmaceuticals. Methods: A spectrophotometric method for the determination of valsartan and ezetimibe was developed using acidic dyes, namely, bromophenol blue (BPB) ...

  12. Problems at simultaneous interpreting education: linguadidactic aspect

    Directory of Open Access Journals (Sweden)

    Pishkova Elena Jurievna

    2015-12-01

    Full Text Available This article is devoted to the problems which students are facing while mastering the skills of a simultaneous interpreting. The article offers a number of exercises to help solve these problems. The authors underline that it is hardly possible to prepare professional simultaneous interpreters among undergraduates for some reasons, and above all because of insufficient time and absence of technical equipment. Nevertheless, the authors conclude by stating the importance of systematic development of students' perceptive skills, attention, memory and reaction required for providing simultaneous interpreting. The main difficulties in simultaneous interpreting training can be connected with three stages of interpreting: listening, comprehension and speaking. Listening challenges deal with a bad speaker’s pronunciation, some technical problems, as well as regional accents or pigeons. As for comprehension problems they are usually connected with the fact that the interpreter isn’t well grounded in the discussion topic, or he isn’t good at topic terminology. It stands to reason that a well-skilled interpreter should prepare to the interpreting topic beforehand. Speaking difficulties can be connected with a poor interpreter’s pronunciation, often caused a stress factor and a lack of topic knowledge. As a rule an excellent pronunciation, a good articulation and a trained voice are necessary for a professional interpreter. The main principal of training exercises given in this article covers all interpreting difficulties mentioned above.

  13. Simultaneous and staged bilateral total hip arthroplasty

    DEFF Research Database (Denmark)

    Lindberg-Larsen, Martin; Joergensen, Christoffer Calov; Husted, Henrik

    2013-01-01

    Bilateral total hip arthroplasty (BTHA) and bilateral simultaneous total hip arthroplasty (BSTHA) are done increasingly. Previous studies evaluating outcomes after bilateral procedures have found different results. The aim of this study was to investigate length of hospital stay (LOS), 30 days re...

  14. Simultaneous Transesterification of Baobab Seed (Adansonia ...

    African Journals Online (AJOL)

    The properties of the Baobab seed methyl ester gave the following: specific gravity, 0.87, pour point, -6 oC, cloud point, 2 oC, flash point, 150 oC, Cetane number , 49, which is comparable with the ASTM D6751 standards for methyl esters. Keywords: Heterogeneous catalyst, Simultaneous transesterification, Baobab seed, ...

  15. Simultaneous Determination of Ciprofloxacin and Tinidazole in ...

    African Journals Online (AJOL)

    Purpose: To develop a simple, sensitive and specific liquid chromatographic method with PDA detection for the simultaneous estimation of ciprofloxacin and tinidazole in tablet dosage form. Methods: Separation was achieved with an Agilent XDB C18, 250 × 4.60 mm 5 μ column, low pressure gradient mode with a ambient ...

  16. Simultaneous determination of naproxen, ibuprofen and diclofenac ...

    African Journals Online (AJOL)

    The occurrence and removal efficiency for naproxen, ibuprofen and diclofenac in two of eThekwini Municipality's wastewater treatment plants (WWTPs), Kingsburgh and Umbilo, were investigated. This paper describes a simple method that can be used routinely for the simultaneous determination of such compounds in the ...

  17. Simultaneous Determination of Seven Constituents in Herbal ...

    African Journals Online (AJOL)

    Simultaneous Determination of Seven Constituents in Herbal Prescription Jaeumganghwa-Tang Using HPLC-PDA. CS Seo, JH Kim, HK Shin. Abstract. A simple and accurate high-performance liquid chromatographic method was applied to the quantitative analysis of seven components of the traditional herbal prescription ...

  18. Simultaneous Visual Discrimination in Asian Elephants

    Science.gov (United States)

    Nissani, Moti; Hoefler-Nissani, Donna; Lay, U. Tin; Htun, U. Wan

    2005-01-01

    Two experiments explored the behavior of 20 Asian elephants ("Elephas aximus") in simultaneous visual discrimination tasks. In Experiment 1, 7 Burmese logging elephants acquired a white+/black- discrimination, reaching criterion in a mean of 2.6 sessions and 117 discrete trials, whereas 4 elephants acquired a black+/white- discrimination in 5.3…

  19. Simultaneous determination of isoniazid and pyrazinamide in ...

    African Journals Online (AJOL)

    Purpose: To develop and validate a new high performance liquid chromatographic (HPLC) method for the simultaneous determination of isoniazid (INH) and pyrazinamide (PZA) in plasma. Methods: A 150 µL aliquot of plasma was mixed with 75 µL of 10 % trichloroacetic acid containing 100 mg/L of acetanilide as the ...

  20. Simultaneous determination of isoniazid and pyrazinamide in ...

    African Journals Online (AJOL)

    Purpose: To develop and validate a new high performance liquid chromatographic (HPLC) method for the simultaneous determination of isoniazid (INH) and pyrazinamide (PZA) in plasma. Methods: A 150 μL aliquot of plasma was mixed with 75 μL of 10 % trichloroacetic acid containing 100 mg/L of acetanilide as the ...

  1. Focusing on Concepts by Covering Them Simultaneously

    Science.gov (United States)

    Shwartz, Pete

    2017-01-01

    "Parallel" pedagogy covers the four mechanics concepts of momentum, energy, forces, and kinematics simultaneously instead of building each concept on an understanding of the previous one. Course content is delivered through interactive videos, allowing class time for group work and student-centered activities. We start with simple…

  2. Simultaneous Quantification of Paracetamol and Meloxicam in ...

    African Journals Online (AJOL)

    Purpose: To develop and validate a simple, rapid and inexpensive RP-HPLC method for the simultaneous estimation of paracetamol and meloxicam in tablets. Methods: For the analysis of the drugs, chromatographic analysis was performed on XTerra symmetry C18 column (100 × 4.6 mm, 5 μ particle size) with mobile ...

  3. Simultaneous estimation of earthquake source parameters and ...

    Indian Academy of Sciences (India)

    This paper presents the simultaneous estimation of source parameters and crustal Q values for small to moderate-size aftershocks (Mw 2.1–5.1) of the Mw 7.7 2001 Bhuj earthquake. The horizontal-component. S-waves of 144 well located earthquakes (2001–2010) recorded at 3–10 broadband seismograph sites in.

  4. Simultaneous estimation of earthquake source parameters and ...

    Indian Academy of Sciences (India)

    This paper presents the simultaneous estimation of source parameters and crustal Q values for small to moderate-size aftershocks ( 2.1–5.1) of the 7.7 2001 Bhuj earthquake. The horizontal-component S-waves of 144 well located earthquakes (2001–2010) recorded at 3–10 broadband seismograph sites in the ...

  5. Optimization of bioethanol production from simultaneous ...

    African Journals Online (AJOL)

    ADOWIE PERE

    ABSTRACT: In this study, bioethanol production from the simultaneous saccharification and fermentation (SSF) of pineapple peels using cellulase and Saccharomyces cerevisiae was investigated. A three-factor Box-behnken design. (BBD) and response surface methodology (RSM) were employed to study the effect of ...

  6. Simultaneous Estimation of Sitagliptin and Metformin in ...

    African Journals Online (AJOL)

    A rapid, simple, specific and precise high-performance thin-layer chromatography (HPTLC) method was developed for the simultaneous estimation of sitagliptin (STG) and metformin (MET) content in a fixed dose pharmaceutical formulation and also in bulk drug. In the developed method, aluminium backed silica gel 60 ...

  7. Development of Three Methods for Simultaneous Quantitative ...

    African Journals Online (AJOL)

    Purpose: To develop new selective, precise, and accurate methods for the simultaneous determination of chlorpheniramine maleate (CHP) and dexamethasone (DX) in the presence of methyl and propyl paraben in phenadone syrup. Methods: In the first two methods, the predictive abilities of principal component ...

  8. Optimization of bioethanol production from simultaneous ...

    African Journals Online (AJOL)

    In this study, bioethanol production from the simultaneous saccharification and fermentation (SSF) of pineapple peels using cellulase and Saccharomyces cerevisiae was investigated. A three-factor Box-behnken design (BBD) and response surface methodology (RSM) were employed to study the effect of broth pH (2-6), ...

  9. Automatic identification of simultaneous equations models

    NARCIS (Netherlands)

    Omtzigt, P.H.

    2003-01-01

    This paper considers within-equation restrictions in simultaneous equation models. It provides an algorithm, which renders them generically identifying. This algorithm works directly on the the restrictions and renders estimation by means of methods that require identification possible. Using this

  10. Simultaneous adsorption and biodegradation of synthetic melanoidin

    African Journals Online (AJOL)

    Being an antioxidant, melanoidin removal through purely biodegradation has been inadequate. Consequently, in the current study, simultaneous adsorption and biodegradation (SAB) was employed in a stirred tank system to remove melanoidin from synthetic wastewater. Mixed microbial consortium was immobilized onto ...

  11. Tracking Control for Two Link Robot Arm Using Neural Networkwith Simultaneous Perturbation Learning Rule

    Science.gov (United States)

    Maeda, Yutaka; Onishi, Hidenori

    Neural networks are widely used for many fields including control problems. When we use a neural network as a controller, the direct inverse control scheme is the simplest approach. However, the scheme using the back-propagation method requires information, e.g. Jacobian, of an objective. If the objective is nonlinear, it will be difficult to know the information. Using the simultaneous perturbation learning rule, we can construct a neuro-controller, which is an inverse system of the objective or a proper controller, under the direct inverse control scheme without any information on the objective. In this paper, we report a tracking control for a two link robot arm using a neuro-controller with the simultaneous perturbation learning rule. Details of the proposed control scheme are described. Some simulation results and a result for a real two link robot arm show that the control scheme is feasible and useful.

  12. Factors that motivate people to undergo cosmetic surgery

    OpenAIRE

    Furnham, Adrian; Levitas, James

    2012-01-01

    A sample of 204 British participants completed a questionnaire that assessed their attitude toward cosmetic surgery as well as measures of self-esteem, life satisfaction, self-rated physical attractiveness, religiosity and media consumption. Two factors emerged from a factor analysis of their attitudes toward surgery: likelihood to undergo, and benefits of undergoing, cosmetic surgery. Females with low self-esteem, low life satisfaction, low self-rated attractiveness and little religious beli...

  13. Glycemic and lipidic profile in diabetic patients undergoing dialysis.

    Science.gov (United States)

    Fortes, Paulo Cezar; Mendes, Jamille Godoy; Sesiuk, Karoline; Marcondes, Letícia Barros; Aita, Carlos Alberto Mayora; Riella, Miguel Carlos; Pecoits-Filho, Roberto

    2010-12-01

    The aim of this study is to assess the clinical care pattern and to compare the lipid and glycemic profile in a group of diabetic patients undergoing both hemodialysis (HD) and peritoneal dialysis (PD) and to correlate these data using biomarkers of cardiovascular risk. The first phase consisted in performing a survey on demographic data, questions about the medical team and glycemic control. In the second phase, patients were assessed through laboratorial data on their glycemic and lipid profile at a single center for HD and PD. 91 patients was the total population; 70 patients (77%) answered the survey; 66 patients (94%) considered the nephrologist the physician responsible for caring for their glycemic control. Second phase: 59 patients were assessed, 29 undergoing HD and 30 undergoing PD. Fifty-seven percent of the patients had HbA1c above 7%; the level of glycemic markers in patients undergoing peritoneal dialysis was significantly higher than in patients undergoing hemodialysis: HbA1c (9.37 ± 0.5) vs. (7.37 ± 0.49) p patients undergoing renal replacement therapy (RRT) is neglected. Peritoneal dialysis is related to the worst level of glycemic markers, possibly due to the glucose content in the dialysis solution, and higher levels from HbA1c have a positive correlation with hyperfibrinogenesis in this population.

  14. Epileptogenic developmental venous anomaly: insights from simultaneous EEG/fMRI.

    Science.gov (United States)

    Scheidegger, Olivier; Wiest, Roland; Jann, Kay; König, Thomas; Meyer, Klaus; Hauf, Martinus

    2013-04-01

    Developmental venous anomalies (DVAs) are associated with epileptic seizures; however, the role of DVA in the epileptogenesis is still not established. Simultaneous interictal electroencephalogram/functional magnetic resonance imaging (EEG/fMRI) recordings provide supplementary information to electroclinical data about the epileptic generators, and thus aid in the differentiation of clinically equivocal epilepsy syndromes. The main objective of our study was to characterize the epileptic network in a patient with DVA and epilepsy by simultaneous EEG/fMRI recordings. A 17-year-old woman with recently emerging generalized tonic-clonic seizures, and atypical generalized discharges, was investigated using simultaneous EEG/fMRI at the university hospital. Previous high-resolution MRI showed no structural abnormalities, except a DVA in the right frontal operculum. Interictal EEG recordings showed atypical generalized discharges, corresponding to positive focal blood oxygen level dependent (BOLD) correlates in the right frontal operculum, a region drained by the DVA. Additionally, widespread cortical bilateral negative BOLD correlates in the frontal and parietal lobes were delineated, resembling a generalized epileptic network. The EEG/fMRI recordings support a right frontal lobe epilepsy, originating in the vicinity of the DVA, propagating rapidly to both frontal and parietal lobes, as expressed on the scalp EEG by secondary bilateral synchrony. The DVA may be causative of focal epilepsies in cases where no concomitant epileptogenic lesions can be detected. Advanced imaging techniques, such as simultaneous EEG/fMRI, may thus aid in the differentiation of clinically equivocal epilepsy syndromes.

  15. Outlining the benefits of Strategic Networking

    Directory of Open Access Journals (Sweden)

    Eva Maria Eckenhofer

    2011-10-01

    Full Text Available Social Networks have attracted enormous interest in the scientific community in recent years. The characteristics, components and impacts of social networks have been studied through different kinds of aspects, such as sociological, geographical, ethnological, political and economical. In economics social network studies have been performed on intra- and inter-organizational levels, though rarely simultaneously. Furthermore the strategic aspects of fostering and controlling informal organizational networks as well as the outcomes of these managerial attempts on the network characteristics and the performance of the organization have not been sufficiently studied yet. However, the need to develop, foster and manage networks efficiently is given for preventing negative effects and provoking positive ones. Therefore this study contributes to scientific theory and practical business development by exploring the influence of Strategic Networking in inter- as well as intra-organizational business-fields. For study the author develops and defines Strategic Networking as the strategic and target-oriented analysis, development, fostering and control of (inter- as well as intra-organizational networks on the basis of trust, with the intention to reach certain (organizational goals and tests its applicability and effects in an extensive survey on three levels: intra-, inter-organizational and regional networks (cluster. The survey showed that Strategic Networking goes in line with favourable network characteristics as well as the success of a firm in terms of financial and non-financial performance measures.

  16. Network Coded Software Defined Networking

    DEFF Research Database (Denmark)

    Hansen, Jonas; Roetter, Daniel Enrique Lucani; Krigslund, Jeppe

    2015-01-01

    . The inherent flexibility of both SDN and NC provides fertile ground to envision more efficient, robust, and secure networking designs, which may also incorporate content caching and storage, all of which are key challenges of the upcoming 5G networks. This article not only proposes the fundamentals......Software defined networking has garnered large attention due to its potential to virtualize services in the Internet, introducing flexibility in the buffering, scheduling, processing, and routing of data in network routers. SDN breaks the deadlock that has kept Internet network protocols stagnant...... for decades, while applications and physical links have evolved. This article advocates for the use of SDN to bring about 5G network services by incorporating network coding (NC) functionalities. The latter constitutes a major leap forward compared to the state-of-the- art store and forward Internet paradigm...

  17. Network Coded Software Defined Networking

    DEFF Research Database (Denmark)

    Krigslund, Jeppe; Hansen, Jonas; Roetter, Daniel Enrique Lucani

    2015-01-01

    Software Defined Networking (SDN) and Network Coding (NC) are two key concepts in networking that have garnered a large attention in recent years. On the one hand, SDN's potential to virtualize services in the Internet allows a large flexibility not only for routing data, but also to manage....... This paper advocates for the use of SDN to bring about future Internet and 5G network services by incorporating network coding (NC) functionalities. The inherent flexibility of both SDN and NC provides a fertile ground to envision more efficient, robust, and secure networking designs, that may also...... incorporate content caching and storage, all of which are key challenges of the future Internet and the upcoming 5G networks. This paper proposes some of the keys behind this intersection and supports it with use cases as well as a an implementation that integrated the Kodo library (NC) into OpenFlow (SDN...

  18. Caracterización físico-mecánica, térmica y morfológica de polímeros de redes interpenetradas con base en poliuretano obtenido a partir de aceite de ricino y almidón modificados/polimetilmetacrilato (PMMA Physico-mechanical, thermal and morphological Behaviour of simultaneous interpenetrating polymer networks based on polyurethane from modified castor oiland starch/poly(Methyl Methacrylate

    Directory of Open Access Journals (Sweden)

    Manuel F. Valero

    2011-01-01

    Full Text Available El aceite de ricino se modificó por transesterificación con pentaeritritol. Paralelamente, se utilizó la reacción de glucosilación con glicerol para dividir el almidón en unidades monosacáridos. El glucósido obtenido reaccionó por transesterificación con el aceite modificado por transesterificación con pentaeritritol. Se determinó el índice de hidroxilo de los poliol-glucósidos en función del contenido de pentaeritritol y almidón utilizados en la síntesis. Se sintetizaron redes interpenetradas de polímero de manera simultánea (SINs con diferentes relaciones en peso poliuretano/PMMA de 100/0, 90/10, 80/20, 70/30, 60/40 y 50/50. Para la síntesis de la red de poliuretano (PU se utilizaron los poliol-glucósidos y diisocianato de isoforona (IPDI o con una relación NCO/OH = 1 y para la síntesis de la red de polimetilmetacrilato (PMMA se utilizó peróxido de benzoílo como agente iniciador y dimetacrilato de etilenglicol como agente entrecruzante. Los SINs se caracterizaron por sus propiedades fisicomecánicas como resistencia al ataque químico, dureza, resistencia a la tensión y elongación de ruptura. La estabilidad térmica de los SINs se determinó usando análisis termogravimétrico (TGA. La morfología de superficie se determinó usando microscopia electrónica de barrido (SEM y mostró una morfología de dos fases para todos los SINs.Castor oil was modified by transesterification with pentaerithritol. In a parallel step, starch was divided into monosaccharide units by glycosylation in order to obtain products with high hydroxyl content. The values of hydroxyl index were measured according to the content of pentaerithritol and starch used in the synthesis. Novel simultaneous interpenetrating polymer networks (SINs of polyurethane (PU and poly(methyl methacrylate (PMMA in different weight ratios of 100/0, 90/10, 80/20, 70/30, 60/40 and 50/50 were prepared based on polyol-glucosides. The polyurethane network was created by

  19. Transcendental and interpolation methods in simultaneous stabilization and simultaneous partial pole placement problems

    Science.gov (United States)

    Ghosh, B. K.

    1986-01-01

    The existence of a compensator which simultaneously renders a given r-tuple of multiinput-multioutput p x m linear dynamical systems internally stable is investigated. In particular, a set of simultaneously stabilizable r-tuples of plants is parametrized, and it is shown that, provided r = max(m,p) or less, the above set is semialgebraic and dense in the space Sigma of r-tuples of plants. An extension of the classical pole placement and stabilization problems is considered, and the simultaneous partial pole placement problem is investigated.

  20. Telecommunication Networks

    DEFF Research Database (Denmark)

    Olsen, Rasmus Løvenstein; Balachandran, Kartheepan; Hald, Sara Ligaard

    2014-01-01

    In this chapter, we look into the role of telecommunication networks and their capability of supporting critical infrastructure systems and applications. The focus is on smart grids as the key driving example, bearing in mind that other such systems do exist, e.g., water management, traffic control......, etc. First, the role of basic communication is examined with a focus on critical infrastructures. We look at heterogenic networks and standards for smart grids, to give some insight into what has been done to ensure inter-operability in this direction. We then go to the physical network, and look...... at the deployment of the physical layout of the communication network and the related costs. This is an important aspect as one option to use existing networks is to deploy dedicated networks. Following this, we look at some generic models that describe reliability for accessing dynamic information. This part...

  1. Networked Identities

    DEFF Research Database (Denmark)

    Ryberg, Thomas; Larsen, Malene Charlotte

    2008-01-01

    In this article we take up a critique of the concept of Communities of Practice (CoP) voiced by several authors, who suggest that networks may provide a better metaphor to understand social forms of organisation and learning. Through a discussion of the notion of networked learning and the critique...... of CoPs we shall argue that the metaphor or theory of networked learning is itself confronted with some central tensions and challenges that need to be addressed. We then explore these theoretical and analytic challenges to the network metaphor, through an analysis of a Danish social networking site. We...... argue that understanding meaning-making and ‘networked identities’ may be relevant analytic entry points in navigating the challenges....

  2. Inefficient preparatory fMRI-BOLD network activations predict working memory dysfunctions in patients with schizophrenia

    Directory of Open Access Journals (Sweden)

    Anja eBaenninger

    2016-03-01

    Full Text Available Patients with schizophrenia show abnormal dynamics and structure of temporally coherent networks (TCNs assessed using fMRI, which undergo adaptive shifts in preparation for a cognitively demanding task. During working memory (WM tasks, patients with schizophrenia show persistent deficits in TCNs as well as EEG indices of WM. Studying their temporal relationship during WM tasks might provide novel insights into WM performance deficits seen in schizophrenia.Simultaneous EEG-fMRI data were acquired during the performance of a verbal Sternberg WM task with two load levels (load 2 & load 5 in 17 patients with schizophrenia and 17 matched healthy controls. Using covariance mapping, we investigated the relationship of the activity in the TCNs before the memoranda were encoded and EEG spectral power during the retention interval. We assessed four TCNs – default mode network (DMN, dorsal attention network (dAN, left and right working memory networks (WMNs – and three EEG bands – theta, alpha, and beta.In healthy controls, there was a load dependent inverse relation between DMN and frontal-midline theta power and an anti-correlation between DMN and dAN. Both effects were not significantly detectable in patients. In addition, healthy controls showed a left-lateralized load-dependent recruitment of the WMNs. Activation of the WMNs was bilateral in patients, suggesting more resources were recruited for successful performance on the WM task.Our findings support the notion of schizophrenia patients showing deviations in their neurophysiological responses before the retention of relevant information in a verbal WM task. Thus, treatment strategies as neurofeedback targeting pre-states could be beneficial as task performance relies on the preparatory state of the brain.

  3. Wireless Networks

    OpenAIRE

    Samaka, Mohammed; Khan, Khaled M.D.

    2007-01-01

    Wireless communication is the fastest-growing field in the telecommunication industry. Wireless networks have grown significantly as an important segment of the communications industry. They have become popular networks with the potential to provide high-speed, high-quality information exchange between two or more portable devices without any wire or conductors. Wireless networks can simply be characterized as the technology that provides seamless access to information, anywhere, anyplace, an...

  4. Enterpreneurial network

    OpenAIRE

    Thoma, Antonela; Nguyen, Lien; Kupsyte, Valdone

    2014-01-01

    Network has become more and more indispensable in the entrepreneurial world. Especially in startup businesses, network is crucial for new entrepreneurs. This project looks at how entrepreneurs in different sectors use network to become successful. We chose to work with three entrepreneurs from three companies that have been operational for a few years and conducted face to face interviews with them. Through the data from the interviews, we analyzed firstly what type of entrepreneurs they are,...

  5. Network security

    CERN Document Server

    Perez, André

    2014-01-01

    This book introduces the security mechanisms deployed in Ethernet, Wireless-Fidelity (Wi-Fi), Internet Protocol (IP) and MultiProtocol Label Switching (MPLS) networks. These mechanisms are grouped throughout the book according to the following four functions: data protection, access control, network isolation, and data monitoring. Data protection is supplied by data confidentiality and integrity control services. Access control is provided by a third-party authentication service. Network isolation is supplied by the Virtual Private Network (VPN) service. Data monitoring consists of applying

  6. Networking Japan

    DEFF Research Database (Denmark)

    Hansen, Annette Skovsted

    HIDA). Many of these alumni have and will in the future exchange ideas and keep contact not only to Japan, but also to fellow alumni around the globe and, thereby, practice south-south exchanges, which are made possible and traceable by their established alumni network and the World Network of Friends...... (WNF). Through the alumni network, Japan continues to infuse ideas to participants and alumni, who interpret and disseminate these ideas through alumni society networks and activities, but their discussions nationally and regionally also get reported back to Japan and affect future policies...

  7. Technical Network

    CERN Multimedia

    2007-01-01

    In order to optimize the management of the Technical Network (TN), to ease the understanding and purpose of devices connected to the TN, and to improve security incident handling, the Technical Network Administrators and the CNIC WG have asked IT/CS to verify the "description" and "tag" fields of devices connected to the TN. Therefore, persons responsible for systems connected to the TN will receive email notifications from IT/CS asking them to add the corresponding information in the network database. Thank you very much for your cooperation. The Technical Network Administrators & the CNIC WG

  8. Simultaneous Multiagent Hyperpolarized 13C Perfusion Imaging

    DEFF Research Database (Denmark)

    von Morze, Cornelius; Bok, Robert A.; Reed, Galen D.

    2014-01-01

    Purpose: To demonstrate simultaneous hyperpolarization and imaging of three 13C-labeled perfusion MRI contrast agents with dissimilar molecular structures ([13C]urea, [13C]hydroxymethyl cyclopropane, and [13C]t-butanol) and correspondingly variable chemical shifts and physiological characteristics......, and to exploit their varying diffusibility for simultaneous measurement of vascular permeability and perfusion in initial preclinical studies. Methods: Rapid and efficient dynamic multislice imaging was enabled by a novel pulse sequence incorporating balanced steady state free precession excitation and spectral...... in simulations. "Tripolarized" perfusion MRI methods were applied to initial preclinical studies with differential conditions of vascular permeability, in normal mouse tissues and advanced transgenic mouse prostate tumors. Results: Dynamic imaging revealed clear differences among the individual tracer...

  9. The dilemma of simultaneous or successive bilingualism

    Directory of Open Access Journals (Sweden)

    Marina Furlan

    2002-12-01

    Full Text Available The study starts from the definition of bilingualism, according to which a person is considered to be bilingual, if she had started to learn (in natural situations two languages from her birth or from early childhood on. The aim of this research work was to assess the existence of any personality differences among "simultaneous" (children exposed to both languages from birth on or at least before the first birthday and "successive" (children exposed to the first language from birth on and to the second language from the toddler period through early childhood bilingual adolescents. The participants were adolescents from secondary schools from the Slovenian coast and from Trieste. Results show that simultaneousness/successiveness of acquisition of the two languages in question doesn't have any impact on personality traits of tested adolescents.

  10. Assessing Cardiovascular Health Using Life′s Simple 7 in a Chinese Population Undergoing Stroke Prevention

    Directory of Open Access Journals (Sweden)

    Qiong Yang

    2015-01-01

    Conclusions: Few Chinese patients undergoing stroke prevention had optimal CVH (determined using LS7. Additionally, fewer patients undergoing secondary prevention had optimal CVH than those undergoing primary prevention. In particular, physical activity and diet status in this population require improvement.

  11. Mirror adaptation in sensory-motor simultaneity.

    Directory of Open Access Journals (Sweden)

    Masataka Watanabe

    Full Text Available BACKGROUND: When one watches a sports game, one may feel her/his own muscles moving in synchrony with the player's. Such parallels between observed actions of others and one's own has been well supported in the latest progress in neuroscience, and coined "mirror system." It is likely that due to such phenomena, we are able to learn motor skills just by observing an expert's performance. Yet it is unknown whether such indirect learning occurs only at higher cognitive levels, or also at basic sensorimotor levels where sensorimotor delay is compensated and the timing of sensory feedback is constantly calibrated. METHODOLOGY/PRINCIPAL FINDINGS: Here, we show that the subject's passive observation of an actor manipulating a computer mouse with delayed auditory feedback led to shifts in subjective simultaneity of self mouse manipulation and auditory stimulus in the observing subjects. Likewise, self adaptation to the delayed feedback modulated the simultaneity judgment of the other subjects manipulating a mouse and an auditory stimulus. Meanwhile, subjective simultaneity of a simple visual disc and the auditory stimulus (flash test was not affected by observation of an actor nor self-adaptation. CONCLUSIONS/SIGNIFICANCE: The lack of shift in the flash test for both conditions indicates that the recalibration transfer is specific to the action domain, and is not due to a general sensory adaptation. This points to the involvement of a system for the temporal monitoring of actions, one that processes both one's own actions and those of others.

  12. Freeform object design and simultaneous manufacturing

    Science.gov (United States)

    Zhang, Wei; Zhang, Weihan; Lin, Heng; Leu, Ming C.

    2003-04-01

    Today's product design, especially the consuming product design, focuses more and more on individuation, originality, and the time to market. One way to meet these challenges is using the interactive and creationary product design methods and rapid prototyping/rapid tooling. This paper presents a novel Freeform Object Design and Simultaneous Manufacturing (FODSM) method that combines the natural interaction feature in the design phase and simultaneous manufacturing feature in the prototyping phase. The natural interactive three-dimensional design environment is achieved by adopting virtual reality technology. The geometry of the designed object is defined through the process of "virtual sculpting" during which the designer can touch and visualize the designed object and can hear the virtual manufacturing environment noise. During the designing process, the computer records the sculpting trajectories and automatically translates them into NC codes so as to simultaneously machine the designed part. The paper introduced the principle, implementation process, and key techniques of the new method, and compared it with other popular rapid prototyping methods.

  13. Implementing inter-organisational service systems : An approach for emerging networks in volatile contexts

    NARCIS (Netherlands)

    Mulira, N.K.

    2007-01-01

    Public organizations in the developing world are undergoing a gradual but irreversible change, due to innovations in information and communications technologies. The emergence of business networks, among such organizations, indicates an increasing interdependence and a search for solutions to regain

  14. Stability analysis of peer-to-peer networks against churn

    Indian Academy of Sciences (India)

    like Internet. In [14], researchers have addressed a more realistic scenario in which a network is subjected to simultaneous targeted and random attacks. The rest of the paper is organized as follows. In §2 we extend the analytical framework [5] to analyse the stability of peer-to-peer networks. Section 3 defines and models ...

  15. Simultaneous MEG and intracranial EEG recordings during attentive reading.

    Science.gov (United States)

    Dalal, Sarang S; Baillet, Sylvain; Adam, Claude; Ducorps, Antoine; Schwartz, Denis; Jerbi, Karim; Bertrand, Olivier; Garnero, Line; Martinerie, Jacques; Lachaux, Jean-Philippe

    2009-05-01

    The relationship between neural oscillations recorded at various spatial scales remains poorly understood partly due to an overall dearth of studies utilizing simultaneous measurements. In an effort to study quantitative markers of attention during reading, we performed simultaneous magnetoencephalography (MEG) and intracranial electroencephalography (iEEG) recordings in four epileptic patients. Patients were asked to attend to a specific color when presented with an intermixed series of red words and green words, with words of a given color forming a cohesive story. We analyzed alpha, beta, and gamma band oscillatory responses to the word presentation and compared the strength and spatial organization of those responses in both electrophysiological recordings. Time-frequency analysis of iEEG revealed a network of clear attention-modulated high gamma band (50-150 Hz) power increases and alpha/beta (9-25 Hz) suppressions in response to the words. In addition to analyses at the sensor level, MEG time-frequency analysis was performed at the source level using a sliding window beamformer technique. Strong alpha/beta suppressions were observed in MEG reconstructions, in tandem with iEEG effects. While the MEG counterpart of high gamma band enhancement was difficult to interpret at the sensor level in two patients, MEG time-frequency source reconstruction revealed additional activation patterns in accordance with iEEG results. Importantly, iEEG allowed us to confirm that several sources of gamma band modulation observed with MEG were indeed of cortical origin rather than EMG muscular or ocular artifact.

  16. ALOHA networks : A game-theoretic approach

    NARCIS (Netherlands)

    Marban, S.; van de Ven, P.; Borm, P.E.M.; Hamers, H.J.M.

    2013-01-01

    In this paper we consider a wireless network consisting of various nodes, where transmissions are regulated by the slotted ALOHA protocol. Nodes using the protocol behave autonomously, and decide at random whether to transmit in a particular time slot. Simultaneous transmissions by multiple nodes

  17. ALOHA networks: A game-theoretic approach

    NARCIS (Netherlands)

    Marbán, S.; Ven, P. van de; Borm, P.; Hamers, H.

    2013-01-01

    In this paper we consider a wireless network consisting of various nodes, where transmissions are regulated by the slotted ALOHA protocol. Nodes using the protocol behave autonomously, and decide at random whether to transmit in a particular time slot. Simultaneous transmissions by multiple nodes

  18. Overlay networks toward information networking

    CERN Document Server

    Tarkoma, Sasu

    2010-01-01

    With their ability to solve problems in massive information distribution and processing, while keeping scaling costs low, overlay systems represent a rapidly growing area of R&D with important implications for the evolution of Internet architecture. Inspired by the author's articles on content based routing, Overlay Networks: Toward Information Networking provides a complete introduction to overlay networks. Examining what they are and what kind of structures they require, the text covers the key structures, protocols, and algorithms used in overlay networks. It reviews the current state of th

  19. Heterodox networks

    DEFF Research Database (Denmark)

    Lala, Purnima; Kumar, Ambuj

    2016-01-01

    It is imperative for the service providers to bring innovation in the network design to meet the exponential growth of mobile subscribers for multi-technology future wireless networks. As a matter of research, studies on providing services to moving subscriber groups aka ‘Place Time Capacity (PTC...

  20. Sensor networks

    NARCIS (Netherlands)

    Chatterjea, Supriyo; Thurston, J.; Kininmonth, S.; Havinga, Paul J.M.

    2006-01-01

    This article describes the details of a sensor network that is currently being deployed at the Great Barrier Reef in Australia. The sensor network allows scientists to retrieve sensor data that has a high spatial and temporal resolution. We give an overview of the energy-efficient data aggregation

  1. Network Protocols

    NARCIS (Netherlands)

    Tanenbaum, A.S.

    1981-01-01

    Dunng the last ten years, many computer networks have been designed, implemented, and put into service in the United States, Canada, Europe, Japan, and elsewhere. From the experience obtamed with these networks, certain key design principles have begun to emerge, principles that can be used to

  2. Probabilistic Networks

    DEFF Research Database (Denmark)

    Jensen, Finn Verner; Lauritzen, Steffen Lilholt

    2001-01-01

    This article describes the basic ideas and algorithms behind specification and inference in probabilistic networks based on directed acyclic graphs, undirected graphs, and chain graphs.......This article describes the basic ideas and algorithms behind specification and inference in probabilistic networks based on directed acyclic graphs, undirected graphs, and chain graphs....

  3. Organizational Networks

    DEFF Research Database (Denmark)

    Sørensen, Ole Henning; Grande, Bård

    1996-01-01

    The paper focuses on the concept of organizational networks. Four different uses of the concept are identified and critically discussed.......The paper focuses on the concept of organizational networks. Four different uses of the concept are identified and critically discussed....

  4. Affective Networks

    OpenAIRE

    Jodi Dean

    2010-01-01

    This article sets out the idea of affective networks as a constitutive feature of communicative capitalism. It explores the circulation of intensities in contemporary information and communication networks, arguing that this circulation should be theorized in terms of the psychoanalytic notion of the drive. The article includes critical engagements with theorists such as Guy Debord, Jacques Lacan, Tiziana Terranova, and Slavoj Zizek.

  5. Network chemistry, network toxicology, network informatics, and network behavioristics: A scientific outline

    OpenAIRE

    WenJun Zhang

    2016-01-01

    In present study, I proposed some new sciences: network chemistry, network toxicology, network informatics, and network behavioristics. The aims, scope and scientific foundation of these sciences are outlined.

  6. Network Affordances

    DEFF Research Database (Denmark)

    Samson, Audrey; Soon, Winnie

    2015-01-01

    This paper examines the notion of network affordance within the context of network art. Building on Gibson's theory (Gibson, 1979) we understand affordance as the perceived and actual parameters of a thing. We expand on Gaver's affordance of predictability (Gaver, 1996) to include ecological...... and computational parameters of unpredictability. We illustrate the notion of unpredictability by considering four specific works that were included in a network art exhibiton, SPEED SHOW [2.0] Hong Kong. The paper discusses how the artworks are contingent upon the parameteric relations (Parisi, 2013......), of the network. We introduce network affordance as a dynamic framework that could articulate the experienced tension arising from the (visible) symbolic representation of computational processes and its hidden occurrences. We base our proposal on the experience of both organising the SPEED SHOW and participating...

  7. Rosuvastatin and cardiovascular events in patients undergoing hemodialysis

    DEFF Research Database (Denmark)

    Fellström, Bengt C; Jardine, Alan G; Schmieder, Roland E

    2009-01-01

    BACKGROUND: Statins reduce the incidence of cardiovascular events in patients at high cardiovascular risk. However, a benefit of statins in such patients who are undergoing hemodialysis has not been proved. METHODS: We conducted an international, multicenter, randomized, double-blind, prospective......: In patients undergoing hemodialysis, the initiation of treatment with rosuvastatin lowered the LDL cholesterol level but had no significant effect on the composite primary end point of death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke. (ClinicalTrials.gov number, NCT00240331.)...... trial involving 2776 patients, 50 to 80 years of age, who were undergoing maintenance hemodialysis. We randomly assigned patients to receive rosuvastatin, 10 mg daily, or placebo. The combined primary end point was death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke...

  8. Factors that motivate people to undergo cosmetic surgery.

    Science.gov (United States)

    Furnham, Adrian; Levitas, James

    2012-01-01

    A sample of 204 British participants completed a questionnaire that assessed their attitude toward cosmetic surgery as well as measures of self-esteem, life satisfaction, self-rated physical attractiveness, religiosity and media consumption. Two factors emerged from a factor analysis of their attitudes toward surgery: likelihood to undergo, and benefits of undergoing, cosmetic surgery. Females with low self-esteem, low life satisfaction, low self-rated attractiveness and little religious beliefs who were heavy television watchers reported a greater likelihood of undergoing cosmetic surgery. Stepwise regression analysis with the two attitude factors as criterion variables showed two major predictors for likelihood: religiousness and low self-esteem, and four major predictors for benefit: religousness, media consumption, life satisfaction and sex. The role of religion is considered in this context.

  9. Robustness of networks formed from interdependent correlated networks under intentional attacks

    Science.gov (United States)

    Liu, Long; Meng, Ke; Dong, Zhaoyang

    2018-02-01

    We study the problem of intentional attacks targeting to interdependent networks generated with known degree distribution (in-degree oriented model) or distribution of interlinks (out-degree oriented model). In both models, each node's degree is correlated with the number of its links that connect to the other network. For both models, varying the correlation coefficient has a significant effect on the robustness of a system undergoing random attacks or attacks targeting nodes with low degree. For a system with an assortative relationship between in-degree and out-degree, reducing the broadness of networks' degree distributions can increase the resistance of systems against intentional attacks.

  10. Rewiring Chemical Networks Based on Dynamic Dithioacetal and Disulfide Bonds.

    Science.gov (United States)

    Orrillo, A Gastón; La-Venia, Agustina; Escalante, Andrea M; Furlan, Ricardo L E

    2018-01-18

    The control of the connectivity between nodes of synthetic networks is still largely unexplored. To address this point we take advantage of a simple dynamic chemical system with two exchange levels that are mutually connected and can be activated simultaneously or sequentially. Dithioacetals and disulfides can be exchanged simultaneously under UV light in the presence of a sensitizer. Crossover reactions between both exchange processes produce a fully connected chemical network. On the other hand, the use of acid, base or UV light connects different nodes allowing network rewiring. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  11. Network evolution of body plans.

    Directory of Open Access Journals (Sweden)

    Koichi Fujimoto

    Full Text Available One of the major goals in evolutionary developmental biology is to understand the relationship between gene regulatory networks and the diverse morphologies and their functionalities. Are the diversities solely triggered by random events, or are they inevitable outcomes of an interplay between evolving gene networks and natural selection? Segmentation in arthropod embryogenesis represents a well-known example of body plan diversity. Striped patterns of gene expression that lead to the future body segments appear simultaneously or sequentially in long and short germ-band development, respectively. Moreover, a combination of both is found in intermediate germ-band development. Regulatory genes relevant for stripe formation are evolutionarily conserved among arthropods, therefore the differences in the observed traits are thought to have originated from how the genes are wired. To reveal the basic differences in the network structure, we have numerically evolved hundreds of gene regulatory networks that produce striped patterns of gene expression. By analyzing the topologies of the generated networks, we show that the characteristics of stripe formation in long and short germ-band development are determined by Feed-Forward Loops (FFLs and negative Feed-Back Loops (FBLs respectively, and those of intermediate germ-band development are determined by the interconnections between FFL and negative FBL. Network architectures, gene expression patterns and knockout responses exhibited by the artificially evolved networks agree with those reported in the fly Drosophila melanogaster and the beetle Tribolium castaneum. For other arthropod species, principal network architectures that remain largely unknown are predicted. Our results suggest that the emergence of the three modes of body segmentation in arthropods is an inherent property of the evolving networks.

  12. Information Flows in Networked Engineering Design Projects

    DEFF Research Database (Denmark)

    Parraguez, Pedro; Maier, Anja

    networks at the project level or in studying the social networks that deliver the “actual information flow”. In this paper we propose and empirically test a model and method that integrates both social and activity networks into one compact representation, allowing to compare actual and required......Complex engineering design projects need to manage simultaneously multiple information flows across design activities associated with different areas of the design process. Previous research on this area has mostly focused on either analysing the “required information flows” through activity...... information flows between design spaces, and to assess the influence that these misalignments could have on the performance of engineering design projects....

  13. Two-Way Multi-Antenna Relaying with Simultaneous Wireless Information and Power Transfer

    Directory of Open Access Journals (Sweden)

    Thanaphat Srivantana

    2017-03-01

    Full Text Available In this paper, we propose various kinds of two-way multi-antenna relaying with simultaneous wireless information and power transfer (SWIPT and investigate their performance. Specifically, we first consider a two-way relay network where two single-antenna end nodes communicate with each other through a multi-antenna relay node that is energy constrained. This relay node harvests energy from the two end nodes and use the harvested energy for forwarding their information. Six relaying schemes that support the considered network then build on the power splitting-based relaying and time switching-based relaying protocols. The average bit error rates of these schemes are evaluated and compared by computer simulations considering several network parameters, including the number of relay antennas, power splitting ratio, and energy harvesting time. Such evaluation and comparison provide useful insights into the performance of SWIPT-based two-way multi-antenna relaying.

  14. Navigability of multiplex temporal network

    Science.gov (United States)

    Wang, Yan; Song, Qiao-Zhen

    2017-01-01

    Real world complex systems have multiple levels of relationships and in many cases, they need to be modeled as multiplex networks where the same nodes can interact with each other in different layers, such as social networks. However, social relationships only appear at prescribed times so the temporal structures of edge activations can also affect the dynamical processes located above them. To consider both factors are simultaneously, we introduce multiplex temporal networks and propose three different walk strategies to investigate the concurrent dynamics of random walks and the temporal structure of multiplex networks. Thus, we derive analytical results for the multiplex centrality and coverage function in multiplex temporal networks. By comparing them with the numerical results, we show how the underlying topology of the layers and the walk strategy affect the efficiency when exploring the networks. In particular, the most interesting result is the emergence of a super-diffusion process, where the time scale of the multiplex is faster than that of both layers acting separately.

  15. Distributed Downlink Power Control for Dense Networks with Carrier Aggregation

    OpenAIRE

    Fazliu, Zana Limani; Chiasserini, Carla-Fabiana; Dell'Aera, Gian Michele; Hamiti, Enver

    2017-01-01

    Given the proven benefits cell densification brings in terms of capacity and coverage, it is certain that 5G networks will be even more heterogeneous and dense. However, as smaller cells are introduced in the network, interference will inevitably become a serious problem as they are expected to share the same radio resources. Another central feature envisioned for future cellular networks is carrier aggregation (CA), which allows users to simultaneously use several component carriers of vario...

  16. Gender and Peer Effects on Performance in Social Networks

    OpenAIRE

    Beugnot, Julie; Fortin, Bernard; Lacroix, Guy; Villeval, Marie Claire

    2017-01-01

    We investigate whether peer effects at work differ by gender and whether gender differences in peer effects -if any- depend on work organization. We develop a social network model with gender heterogeneity that we test in a real-effort laboratory experiment. We compare sequential networks in which information flows from peers to the worker and simultaneous networks where it disseminates bi-directionally. We identify strong gender differences as females disregard their peers’ performance in si...

  17. Free space optical networks for ultra-broad band services

    CERN Document Server

    Kartalopoulos, Stamatios V

    2011-01-01

    "Free Space Optical Network is a next generation communication network which uses optical waves instead of microwaves, potentially offering faster communication with ultra band width, meaning more complex communication services can be simultaneously offered. This book describes the network concepts in simple language starting with point-to-point free space optics basics and discusses networking, interoperability with existing communication network, and security. An ideal resource for communication professionals just entering the free space optical communication field and graduate students majoring in optical communications"--Provided by publisher.

  18. Reconstructing cancer drug response networks using multitask learning.

    Science.gov (United States)

    Ruffalo, Matthew; Stojanov, Petar; Pillutla, Venkata Krishna; Varma, Rohan; Bar-Joseph, Ziv

    2017-10-10

    Translating in vitro results to clinical tests is a major challenge in systems biology. Here we present a new Multi-Task learning framework which integrates thousands of cell line expression experiments to reconstruct drug specific response networks in cancer. The reconstructed networks correctly identify several shared key proteins and pathways while simultaneously highlighting many cell type specific proteins. We used top proteins from each drug network to predict survival for patients prescribed the drug. Predictions based on proteins from the in-vitro derived networks significantly outperformed predictions based on known cancer genes indicating that Multi-Task learning can indeed identify accurate drug response networks.

  19. Simultaneous distribution of AC and DC power

    Science.gov (United States)

    Polese, Luigi Gentile

    2015-09-15

    A system and method for the transport and distribution of both AC (alternating current) power and DC (direct current) power over wiring infrastructure normally used for distributing AC power only, for example, residential and/or commercial buildings' electrical wires is disclosed and taught. The system and method permits the combining of AC and DC power sources and the simultaneous distribution of the resulting power over the same wiring. At the utilization site a complementary device permits the separation of the DC power from the AC power and their reconstruction, for use in conventional AC-only and DC-only devices.

  20. Simultaneous bilateral total hip arthroplasties in nonagenarians.

    Science.gov (United States)

    Power, F R; Cawley, D T; Curtin, P D

    2017-11-01

    Total hip arthroplasty (THA) is an effective and durable treatment option for hip osteoarthritis (OA). As life expectancy continues to increase, so too will the demand for joint arthroplasty in the 10th decade of life, frequently in cases involving osteoarthritis of both hips. Simultaneous bilateral total hip arthroplasty (SBTHA) is a valuable therapeutic option in appropriately selected patients with bilateral degenerative hip disease, although its use in the very elderly is poorly reported on in the literature. A case of bilateral hip OA successfully treated with SBTHA in a nonagenarian is presented and the literature is reviewed.

  1. Resolution enhancement using simultaneous couple illumination

    Science.gov (United States)

    Hussain, Anwar; Martínez Fuentes, José Luis

    2016-10-01

    A super-resolution technique based on structured illumination created by a liquid crystal on silicon spatial light modulator (LCOS-SLM) is presented. Single and simultaneous pairs of tilted beams are generated to illuminate a target object. Resolution enhancement of an optical 4f system is demonstrated by using numerical simulations. The resulting intensity images are recorded at a charged couple device (CCD) and stored in the computer memory for further processing. One dimension enhancement can be performed with only 15 images. Two dimensional complete improvement requires 153 different images. The resolution of the optical system is extended three times compared to the band limited system.

  2. Simultaneous scheduling of machines and mobile robots

    DEFF Research Database (Denmark)

    Dang, Vinh Quang; Nielsen, Izabela Ewa

    2013-01-01

    in terms of their advanced ability to perform tasks at machines by using their manipulation arms. The mobile robots thus have to be scheduled in relation to scheduling of machines so as to increase the efficiency of the overall system. The performance criterion is to minimize time required to complete all......This paper deals with the problem of simultaneously scheduling machines and a number of autonomous mobile robots in a flexible manufacturing system (FMS). Besides capability of transporting materials between machines, the considered mobile robots are different from other material handling devices...

  3. Probabilistic Models and Process Calculi for Mobile Ad Hoc Networks

    DEFF Research Database (Denmark)

    Song, Lei

    , thus the network topology may undergo constant changes. Moreover the devices in an MANET are loosely connected not depending on pre-installed infrastructure or central control components, they exchange messages via wireless connections which are less reliable compared to wired connections. Therefore...... issues in MANETs e.g. mobility and unreliable connections. Specially speaking, 1. We first propose a discrete probabilistic process calculus with which we can model in an MANET that the wireless connection is not reliable, and the network topology may undergo changes. We equip each wireless connection...

  4. Electrical responses and spontaneous activity of human iPS-derived neuronal networks characterized for three-month culture with 4096-electrode arrays

    Directory of Open Access Journals (Sweden)

    Hayder eAmin

    2016-03-01

    Full Text Available The recent availability of human induced pluripotent stem cells (hiPSCs holds great promise as a novel source of human-derived neurons for cell and tissue therapies as well as for in vitro drug screenings that might replace the use of animal models. However, there is still a considerable lack of knowledge on the functional properties of hiPSC-derived neuronal networks, thus limiting their application. Here, upon optimization of cell culture protocols, we demonstrate that both spontaneous and evoked electrical spiking activities of these networks can be characterized on-chip by taking advantage of the resolution provided by CMOS multielectrode arrays (CMOS-MEAs. These devices feature a large and closely-spaced array of 4096 simultaneously recording electrodes and multi-site on-chip electrical stimulation. Our results show that networks of human-derived neurons can respond to electrical stimulation with a physiological repertoire of spike waveforms after three months of cell culture, a period of time during which the network undergoes the expression of developing patterns of spontaneous spiking activity. To achieve this, we have investigated the impact on the network formation and on the emerging network-wide functional properties induced by different biochemical substrates, i.e. poly-dl-ornithine (PDLO, poly-l-ornithine (PLO, and polyethylenimine (PEI, that were used as adhesion promoters for the cell culture. Interestingly, we found that neuronal networks grown on PDLO coated substrates show significantly higher spontaneous firing activity, reliable responses to low-frequency electrical stimuli, and an appropriate level of PSD-95 that may denote a physiological neuronal maturation profile and synapse stabilization. However, our results also suggest that even three-month culture might not be sufficient for human-derived neuronal network maturation. Taken together, our results highlight the tight relationship existing between substrate coatings

  5. Electrical Responses and Spontaneous Activity of Human iPS-Derived Neuronal Networks Characterized for 3-month Culture with 4096-Electrode Arrays.

    Science.gov (United States)

    Amin, Hayder; Maccione, Alessandro; Marinaro, Federica; Zordan, Stefano; Nieus, Thierry; Berdondini, Luca

    2016-01-01

    The recent availability of human induced pluripotent stem cells (hiPSCs) holds great promise as a novel source of human-derived neurons for cell and tissue therapies as well as for in vitro drug screenings that might replace the use of animal models. However, there is still a considerable lack of knowledge on the functional properties of hiPSC-derived neuronal networks, thus limiting their application. Here, upon optimization of cell culture protocols, we demonstrate that both spontaneous and evoked electrical spiking activities of these networks can be characterized on-chip by taking advantage of the resolution provided by CMOS multielectrode arrays (CMOS-MEAs). These devices feature a large and closely-spaced array of 4096 simultaneously recording electrodes and multi-site on-chip electrical stimulation. Our results show that networks of human-derived neurons can respond to electrical stimulation with a physiological repertoire of spike waveforms after 3 months of cell culture, a period of time during which the network undergoes the expression of developing patterns of spontaneous spiking activity. To achieve this, we have investigated the impact on the network formation and on the emerging network-wide functional properties induced by different biochemical substrates, i.e., poly-dl-ornithine (PDLO), poly-l-ornithine (PLO), and polyethylenimine (PEI), that were used as adhesion promoters for the cell culture. Interestingly, we found that neuronal networks grown on PDLO coated substrates show significantly higher spontaneous firing activity, reliable responses to low-frequency electrical stimuli, and an appropriate level of PSD-95 that may denote a physiological neuronal maturation profile and synapse stabilization. However, our results also suggest that even 3-month culture might not be sufficient for human-derived neuronal network maturation. Taken together, our results highlight the tight relationship existing between substrate coatings and emerging network

  6. Social networks

    CERN Document Server

    Etaner-Uyar, A Sima

    2014-01-01

    The present volume provides a comprehensive resource for practitioners and researchers alike-both those new to the field as well as those who already have some experience. The work covers Social Network Analysis theory and methods with a focus on current applications and case studies applied in various domains such as mobile networks, security, machine learning and health. With the increasing popularity of Web 2.0, social media has become a widely used communication platform. Parallel to this development, Social Network Analysis gained in importance as a research field, while opening up many

  7. Network Warrior

    CERN Document Server

    Donahue, Gary

    2011-01-01

    Pick up where certification exams leave off. With this practical, in-depth guide to the entire network infrastructure, you'll learn how to deal with real Cisco networks, rather than the hypothetical situations presented on exams like the CCNA. Network Warrior takes you step by step through the world of routers, switches, firewalls, and other technologies based on the author's extensive field experience. You'll find new content for MPLS, IPv6, VoIP, and wireless in this completely revised second edition, along with examples of Cisco Nexus 5000 and 7000 switches throughout. Topics include: An

  8. On the degelation of networks - Case of the radiochemical degradation of methyl methacrylate - ethylene glycol dimethacrylate copolymers

    Science.gov (United States)

    Richaud, Emmanuel; Gilormini, Pierre; Verdu, Jacques

    2016-05-01

    Methyl methacrylate networks were synthetized and submitted to radiochemical degradation. Ageing was monitored by means of sol-gel analysis and glass transition temperature measurements. Networks were shown to undergo exclusively chain scission process leading to the degelation of network. The critical conversion degree corresponding to degelation (loss of all elastically active chains) is discussed regarding a statistical theory.

  9. On the degelation of networks – Case of the radiochemical degradation of methyl methacrylate – ethylene glycol dimethacrylate copolymers

    Energy Technology Data Exchange (ETDEWEB)

    Richaud, Emmanuel; Gilormini, Pierre; Verdu, Jacques [Arts et Métiers ParisTech, CNRS, PIMM UMR 8006, 151 bd de l’Hôpital, 75013 Paris (France)

    2016-05-18

    Methyl methacrylate networks were synthetized and submitted to radiochemical degradation. Ageing was monitored by means of sol-gel analysis and glass transition temperature measurements. Networks were shown to undergo exclusively chain scission process leading to the degelation of network. The critical conversion degree corresponding to degelation (loss of all elastically active chains) is discussed regarding a statistical theory.

  10. Estimating individual listeners’ auditory-filter bandwidth in simultaneous and non-simultaneous masking

    DEFF Research Database (Denmark)

    Buchholz, Jörg; Caminade, Sabine; Strelcyk, Olaf

    2010-01-01

    and assuming a rounded-exponential filter shape. If a forward masking paradigm is used instead of simultaneous masking, filter estimates typically show significantly sharper tuning. This difference in frequency selectivity has commonly been related to spectral suppression mechanisms observed in the cochlea......Frequency selectivity in the human auditory system is often measured using simultaneous masking of tones presented in notched noise. Based on such masking data, the equivalent rectangular bandwidth (ERB) of the auditory filters can be derived by applying the power spectrum model of masking...... the reliability of the individual estimates, a statistical resampling method is applied. It is demonstrated that a rather large set of experimental data is required to reliably estimate auditory filter bandwidth, particularly in the case of simultaneous masking. The poor overall reliability of the filter...

  11. 75 FR 26256 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-05-11

    ... HUMAN SERVICES Centers for Disease Control and Prevention Agency Forms Undergoing Paperwork Reduction... annual survey and influenza-like illness, Respiratory and Enterovirus surveillance, rabies, waterborne... Virus Surveillance System 90 52 10/60 (NREVSS) Rabies (electronic) 50 12 8/60 Rabies (paper) 3 12 15/60...

  12. 75 FR 65488 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-10-25

    ... Human Rabies Patient Info 50 1 15/60 Waterborne Diseases Outbreak Form 57 1 20/60 Cholera and other... HUMAN SERVICES Centers for Disease Control and Prevention Agency Forms Undergoing Paperwork Reduction... annual survey and influenza-like illness, Respiratory and Enterovirus surveillance, rabies, waterborne...

  13. 75 FR 4824 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-01-29

    ... HUMAN SERVICES Centers for Disease Control and Prevention Agency Forms Undergoing Paperwork Reduction Act Review The Centers for Disease Control and Prevention (CDC) publishes a list of information... evaluate cervical cancer screening methods and the use of Human Papillomavirus DNA tests. A supplemental...

  14. 75 FR 26257 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-05-11

    ... prior to the commute and health measurements for lung function, lung inflammatory markers, heart rate... HUMAN SERVICES Centers for Disease Control and Prevention Agency Forms Undergoing Paperwork Reduction Act Review The Centers for Disease Control and Prevention (CDC) publishes a list of information...

  15. 76 FR 74064 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-11-30

    ... HUMAN SERVICES Centers for Disease Control and Prevention Agency Forms Undergoing Paperwork Reduction.... Healthcare Worker 600 200 20/60 Demographic Data. Exposure to Blood/Body 600 50 1 Fluids. Healthcare Worker.... Occ Health RN Healthcare Worker 600 300 10/60 Vaccination History. Occ Health RN Healthcare Worker...

  16. Post-operative morbidity of the obese patient undergoing posterior ...

    African Journals Online (AJOL)

    Outcome measures: Post-operative morbidity measures – infection, seroma, pulmonary embolism, urinary tract infection, neurological injury and dural tears. Methods: One hundred consecutive patients undergoing posterior lumbar spine surgery were enrolled in the study. Three fellowship trained attending orthopaedic ...

  17. 76 FR 60498 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-09-29

    ... public. Refine message concepts and to test draft materials for clarity, salience, appeal, and... should be received within 30 days of this notice. Proposed Project Health Message Testing System (OMB No... message to the public, the message always undergoes scientific review. However, even though the message is...

  18. 78 FR 21126 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-04-09

    ... dental assistants. Furthermore, recruitment of health care workers will only be from hospitals and... HUMAN SERVICES Centers for Disease Control and Prevention Agency Forms Undergoing Paperwork Reduction... designed to collect information about work history, workplace exposures and asthma health from workers in...

  19. 75 FR 20601 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-04-20

    ... System (AIRS)--New--Air Pollution and Respiratory Health Branch (APRHB), National Center for Environmental Health (NCEH), Centers for Disease Control and Prevention (CDC). Background and Brief Description... HUMAN SERVICES Centers for Disease Control and Prevention Agency Forms Undergoing Paperwork Reduction...

  20. [Access to somatic care for patients undergoing psychiatric treatment].

    Science.gov (United States)

    Cabaret, Wanda

    2010-01-01

    In France, there is no across-the-board formal connection between psychiatric and somatic treatment and the somatic care of patients undergoing psychiatric treatment remains very heterogeneous and inadequate. Despite some attempts at providing structure, it is the place of the physician which must be examined and optimised.

  1. Management of sickle cell disease in patients undergoing cardiac surgery.

    Science.gov (United States)

    Crawford, Todd C; Carter, Michael V; Patel, Rina K; Suarez-Pierre, Alejandro; Lin, Sophie Z; Magruder, Jonathan Trent; Grimm, Joshua C; Cameron, Duke E; Baumgartner, William A; Mandal, Kaushik

    2017-02-01

    Sickle cell disease is a life-limiting inherited hemoglobinopathy that poses inherent risk for surgical complications following cardiac operations. In this review, we discuss preoperative considerations, intraoperative decision-making, and postoperative strategies to optimize the care of a patient with sickle cell disease undergoing cardiac surgery. © 2017 Wiley Periodicals, Inc.

  2. Postoperative atrial fibrillation in patients on statins undergoing ...

    African Journals Online (AJOL)

    LW Drummond

    2013-04-02

    Apr 2, 2013 ... Results: Statins did not decrease the incidence of postoperative AF in patients undergoing isolated cardiac valve surgery [odds ratio (OR) 1.19 ... myocardial infarction, heart failure, acute kidney injury, infection, neurocognitive .... Patients with valvular heart disease were not included in the cardiac surgery ...

  3. Quality of Life in End Stage Renal Failure Patients Undergoing ...

    African Journals Online (AJOL)

    We assessed the quality of life of 45 patients with end stage renal failure undergoing dialysis in Mauritius using the standard United Kingdom version of the Short Form 36 Items Health Survey (SF36) questionnaire. Our findings showed that gender, level of social and emotional support, marital status, and travel time were ...

  4. Clinical effect of Fuzheng quyu therapy in patients undergoing ...

    African Journals Online (AJOL)

    Clinical effect of Fuzheng quyu therapy in patients undergoing radiotherapy after cervical carcinoma surgery. ... Tropical Journal of Pharmaceutical Research ... only, whereas those in the study group received treatment designed to nourish healthy vital energy and eliminate blood stasis in addition to radiotherapy. Changes ...

  5. Clinical effect of Fuzheng quyu therapy in patients undergoing ...

    African Journals Online (AJOL)

    Methods: One hundred and twenty patients who underwent radiotherapy after cervical carcinoma ... breast cancer [1]. Currently, radiotherapy and surgical therapy are the standard treatments for patients with cervical carcinoma. However, some patients cannot tolerate ..... non-small cell lung cancer patients undergoing.

  6. Clinical effect of Fuzheng quyu therapy in patients undergoing ...

    African Journals Online (AJOL)

    Purpose: To examine the clinical effect of Fuzheng Quyu therapy in patients undergoing radiotherapy after cervical carcinoma ... Conclusion: Herbal therapy designed to nourish vital energy and eliminates blood stasis relieves high- level blood coagulation ..... improves immunity, regulates neural and endocrine functions ...

  7. HIV Seroprevalence in Patients Undergoing Ophthalmic Surgery in ...

    African Journals Online (AJOL)

    Aim: The aim of this study was to determine the number of HIV positive cases undergoing ophthalmic surgery at two centres in Nigeria and to assess if routine testing is clinically or economically effective. Methods: All patients listed for ophthalmic surgery in two eye units in southern Nigeria during a six-month period in 2005,

  8. Reported analgesic administration to rabbits undergoing experimental surgical procedures

    Directory of Open Access Journals (Sweden)

    Leach Matthew C

    2011-02-01

    Full Text Available Abstract Background It has become widely accepted that whenever animals are used in scientific procedures, the 3Rs principle of replacement, reduction and refinement described by William Russell and Rex Burch should be adhered to. Animals should be replaced with non-sentient alternatives if possible, the number of animals used should be reduced and experimental procedures should be refined to minimise pain, suffering and distress. Administration of analgesic agents to animals undergoing surgical procedures is a refinement used to alleviate pain. In this study, a structured literature review was carried out to examine current trends in analgesic administration to rabbits undergoing experimental surgical procedures. Results 128 papers from 51 peer-reviewed journals were selected for inclusion in this review. Reporting administration of systemic analgesia to rabbits in peer-reviewed scientific papers increased significantly from 16% to 50% between 1995-1997 and 2005-2007 (P P Conclusions Although this review provides evidence that systemic analgesic administration to rabbits undergoing surgical procedures is increasing, rabbits do not always receive analgesia when they undergo experimental surgery. Other practices in rabbit perioperative care that could be improved, highlighted by this survey include: 1 changing the timing of analgesic administration by giving systemic analgesics pre- or perioperatively rather than only postoperatively, 2 using multimodal analgesia when pain is likely to be moderate to severe and 3 increasing the use of non-steroidal anti-inflammatory drugs and use of other techniques such as epidural analgesia particularly for orthopaedic procedures.

  9. 75 FR 14164 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-03-24

    ... health objectives for treatment of tuberculosis (TB), prevention of multi-drug resistance, and... HUMAN SERVICES Centers for Disease Control and Prevention Agency Forms Undergoing Paperwork Reduction Act Review The Centers for Disease Control and Prevention (CDC) publishes a list of information...

  10. 75 FR 43987 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-07-27

    ..., and TB Prevention (NCHHSTP), Centers for Disease Control and Prevention (CDC). Background and Brief... HUMAN SERVICES Centers for Disease Control and Prevention Agency Forms Undergoing Paperwork Reduction Act Review The Centers for Disease Control and Prevention (CDC) publishes a list of information...

  11. 75 FR 38104 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-07-01

    ... From the Federal Register Online via the Government Publishing Office ] DEPARTMENT OF HEALTH AND HUMAN SERVICES Centers for Disease Control and Prevention Agency Forms Undergoing Paperwork Reduction.... Other variables for segmentation may include, but not be limited to, geography and language. Two youth...

  12. 77 FR 70782 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-11-27

    ... patients who undergo screening by FIT or colonoscopy until it reaches a target number of responses. Targets... should be received within 30 days of this notice. ] Proposed Project Colorectal Cancer Control Program... Cancer (CRC) is the second leading cause of cancer- related deaths in the United States, following lung...

  13. Rosuvastatin and cardiovascular events in patients undergoing hemodialysis

    NARCIS (Netherlands)

    Fellström, Bengt C.; Jardine, Alan G.; Schmieder, Roland E.; Holdaas, Hallvard; Bannister, Kym; Beutler, Jaap; Chae, Dong-Wan; Chevaile, Alejandro; Cobbe, Stuart M.; Grönhagen-Riska, Carola; de Lima, José J.; Lins, Robert; Mayer, Gert; McMahon, Alan W.; Parving, Hans-Henrik; Remuzzi, Giuseppe; Samuelsson, Ola; Sonkodi, Sandor; Sci, D.; Süleymanlar, Gultekin; Tsakiris, Dimitrios; Tesar, Vladimir; Todorov, Vasil; Wiecek, Andrzej; Wüthrich, Rudolf P.; Gottlow, Mattis; Johnsson, Eva; Zannad, Faiez; Fellström, B.; Zannad, F.; Schmieder, R. E.; Holdaas, H.; Jardine, A. G.; Johnsson, E.; Gottlow, M.; Bannister, K.; Beutler, J.; Chae, D.; Cobbe, S. M.; Grönhagen-Riska, C.; de Lima, J.; Lins, R.; McMahon, A.; Mayer, G.; Parving, H.-H.; Chevaile, A.; Remuzzi, G.; Samuelsson, O.; Sonkodi, S.; Süleymanlar, G.; Tsakiris, D.; Tesar, V.; Todorov, V.; Wiecek, A.; Wüthrich, R. P.; Dargie, H.; Ritz, E.; Wedel, H.; Zwinderman, A. H.; Brady, A.; Deighan, C.; Macfarlane, P.; Stott, D.; Gillies, A.; Carney, S.; Faull, R.; Surany, M.; Saltissi, D.; Fraenkel, M.; Mount, P.; Irish, A.; Chan, D.; Dogra, S.; Wei, S.; Roger, S.; Pollock, C.; Cooper, B.; Brown, F.; Healy, H.; Hutchinson, B.; Boudville, N.; Senaratne, S.; Luxton, J.; Disney, A.; Russ, G.; Isbel, N.; Johnson, D.; Wong, J.; Herzig, K.; Walker, R.; Leikis, M.; Masterson, R.; Perkovic, V.; Kramar, R.; Robl, B.; Stummvoll, H.-K.; Holzer, H.; Prager, R.; Graf, H.; Neyer, U.; Kovarik, J.; Balcke, P.; Muyshondt, I.; Claes, K.; Maes, B.; Jadoul, M.; Dupont, P.; Marchal, M.; Pirson, Y.; Cambier, P.; Robin, M.; Warling, X.; Tielemans, C.; van der Niepen, P.; van Vlem, B.; Billiouw, J.-M.; de Meester, J.; Krzesinski, J.-M.; Dubois, B.; Delanaye, P.; Gowdak, L.; Barbosa, A.; Abreu, P.; Balda, C.; Canziani, M. E.; Watanabe, R.; Barata, R.; Lisboa, N.; Vilarinho, R.; Pecoits, R.; Teixeira, P.; Fortes, P.; Kraev, Z.; Koteva, A.; Georgiev, M.; Krivoshiev, S.; Popov, A.; Baldev, T.; Terziiska, G.; Rangelov, R.; Ekova, D.; Vitanova, L.; Mitova, V.; Videnova, N.; Dimitrova, B.; Dosev, D.; Vasileva, V.; Dimitrakov, D.; Blagov, B.; Nikolov, D.; Tilkijan, E.; Kapon, E.; Stavrev, P.; Guncheva, N.; Paunova, P.; Tashkov, B.; Bojadziev, D.; Popova, G.; Delibaltov, I.; Markov, M.; Koleva, N.; Petrova, M.; Berall, M.; Pierratos, A.; Mendelssohn, D.; Hercz, G.; Burgess, E.; Cournoyer, S.; Giroux, C.; Soltys, G.; Savoie, L.; Brunet, S.; Begin, V.; Duncan, J.; Yeung, C.; Cameron, E.; Jastrzebski, J.; Shapiro, J.; Copland, M.; Keown, P.; Singh, R.; Jolly, S.; Mustata, S.; Kates, D.; Jung, B.; Jamal, A.; Levin, A.; Chiu, A.; Chan-Yan, C.; Landsberg, D.; Macrae, J. M.; Gill, J.; de Luca, L.; Kiaii, M.; Taylor, P.; Lambert, F.; Berrard, J.; Youmbissi, J.; Bessette, M.; Turcot, R.; Moreau, V.; Davidman, M.; Bencovitch, D.; Frisch, G.; Lipman, M.; Pannu, N.; Davison, S.; Gourishankar, S.; Rehman, F.; Muirhead, N.; House, A.; Pichette, V.; Leblanc, M.; Prud'Homme, L.; Marcotte, J.; Desjardins, M.-H.; Raymond, M.; Tremblay, R.; Richardson, R.; Chan, C.; Sohi, P.; Pippy, C.; Gogan, N.; Handa, S.; Soroka, S.; Hirsh, D.; Panek, R.; Keough-Ryan, T.; Ting, R.; Fung, J.; Ng, P.; Tam, P.; Chow, S.; Zacharias, J.; Wu, G.; Kim, D.; Wong, G.; Wadgymar, J.; Wong, M.; Schuld, R.; Bitterova, Z.; Hanek, T.; Dvorak, K.; Pavlikova, Z.; Fixa, P.; Zahradnik, J.; Suchanova, J.; Krizova, E.; Zavada, J.; Lachmanova, J.; Mokrejsova, M.; Viklicky, O.; Lyerova, L.; Urbanova, M.; Syrovatka, P.; Kukura, S.; Svara, F.; Sagova, M.; Sulkova, S.; Polakovic, V.; Ryba, M.; Koci, P.; Ladefoged, S.; Jensen, H.; Rasmussen, K.; Nielsen, G.; Østergaard, O.; Nielsen, A.; Lynggaard, F.; Otte, K.; Steffensen, G.; Løkkegaard, N.-J.; Danielsen, H.; Hasling, C.; Hansen, S.; Freese, P.; Hansen, J.; Rasmussen, E.; Nielsen, F.; Egfjord, M.; Szpirt, W.; Mustonen, J.; Saha, H.; Ala-Houhala, I.; Ekstrand, A.; Honkanen, E.; Ylinen, K.; Malmström, R.; Rauta, V.; Tertti, R.; Metsärinne, K.; Heiro, M.; Koivuviita, N.; Kananen, K.; Salmela, A.; Lepistö, P.; Ikäheimo, R.; Pikkujämsä, S.; Karhapää, P.; Lumiaho, A.; Pulkkinen, A.; Helanterä, A.; Wallin, M.; Kolunen, M.; Asola, M.; Huhti, J.; Jääskeläinen, K.; Nuortimo, J.; Stenborg, M.; Erkinheimo, J.; Huuskonen, M.; Paldanius, R.; Helin, K.; Norvio, L.; Haapala, M.; Lindström, C.-J.; Monkam, R.; Bataille, P.; Nour, D.; Bouzerjnidj, M.; Wheatley, P.; Billion, S.; Brignon, P.; Maaz, M.; Charpentier, B.; Durrbach, A.; Djeffal, R.; Snanoudj, R.; El Esper, N.; Choukroun, G.; Dahmane, D.; Fessi, H.; Kessler, M.; Bellou-Zerrouki, M.; Cao-Huu, T.; Lamotte, C.; Lebleu, J.; Luong, C.-N.; Bouali, B.; Reach, I.; Mac-Namara, E.; Bourdon, F.; Majdanali, G.; Bouffandeau, A.; Chaghouri, B.; Hugot, V.; Torres, P. A. U.; Binaut, R.; Fleury, D.; Bacri, J.-L.; Maisonneuve, N.; Vanhille, P.; Lemaitre, V.; Lambrey, G.; Zaoui, P.; Kuentz, F.; Palancin, P.; Milongo, R.; Hachache, T.; Dehais, F.; Dupuy, P.; Wehbe, B.; Benarbia, S.; Yver, L.; Pujo, M.; Fourcade, J.; Philit, J.-B.; Ballé, C.; Bambauer, R.; Bittner, K.; Dragoun, G.-P.; Matzkies, F.; Hartmann, H.; Hoffmann, H.-D.; Kliem, V.; Kraatz, U.; Kraatz, G.; Krämer, H.; Krämer, W.; Krämer-Guth, A.; Kühn, R.; Kulzer, P.; Kurth, C.; Liebl, R.; Merker, L.; Meyer, T.; Mohler, C.; Neumann, K.; Nikolay, J.; Reiter, E.; Schannen, G.; Scherberich, J.; Schmieder, R.; Sperschneider, H.; Wagner, J.; Bast, I.; Anding-Rost, K.; Passauer, J.; Scheuermann, E.; Krause, R.-D.; Pommer, W.; Bhandari, S.; Webb, A.; Lewis, D.; Eadington, D.; Collinson, H.; Sellars, L.; Svreck, P.; Brown, A.; Bow, A.; Ahmed, S.; Severn, A.; Henderson, I.; Jardine, A.; Junor, B.; Nolan, C.; Geddes, C.; McGregor, E.; Mark, P.; Patel, R.; Rodger, S.; Main, J.; Reaich, D.; Paterson, A.; Maxwell, P.; Brown, H.; Finn, M.; O'Donoghue, D.; Wood, G.; Espinosa, O.; Middleton, R.; Woodrow, G.; Wright, M.; Rowe, P.; Cramp, H.; Tse, W.; Fox, J.; Macteir, R.; Isles, C.; Streather, C.; Semple, D.; Banerjee, D.; Mitra, S.; Gokal, R.; Bubtana, A.; Asari, A.; Jeffrey, R.; Mumtaz, R.; El Nahas, M.; Kwan, J.; Kumwenda, M.; Douglas, A.; Harron, C.; Courtney, A.; Sunil, J.; Garrett, P.; Maddekar, N.; Bergin, E.; Harty, J.; Conway, B.; Hollywood, M.; Macgregor, M.; Mackenzie, P.; Papagalanis, N.; Biblaki, D.; Ntatsis, G.; Kaperonis, N.; Siapera, V.; Iatrou, C.; Kontouli, T.; Spanou, E.; Kalocheretis, P.; Zerbala, S.; Sofroniadou, S.; Kelesidis, A.; Xanthopoulou, K.; Tsouchnikas, I.; Papakonstantinou, S.; Sobolos, K.; Bamichas, G.; Siamopoulos, K.; Gouva, C.; Kitsos, A.; Katopodis, K.; Nikolopoulos, P.; Vargemezis, V.; Thodis, E.; Yannatos, E.; Katartzi, K.; Panagoutsos, S.; Kiss, E.; Zsom, M.; Kiss, I.; Lakatos, A.; Fodor, E.; Nádori, E.; Arkossy, O.; Koroknai, L.; Mázik, R.; Vezekényi, Z.; Kovács, A.; Samir, N.; Akócsi, K.; Varga, G.; Ferenczi, S.; Villányi, B.; Schneider, K.; Vinkovits, S.; Czégány, Z.; Onody, Z.; Szegedi, J.; Valikovics, F.; Angyal, S.; Zilahi, Z.; Ladányi, E.; Széll, J.; Berta, K.; Szamosfalvi, B.; Ambrus, C.; Deák, G.; Faludi, M.; Molnár, M.; Zakar, G.; Varga, D.; Kovács, L.; Tüsér, Z.; Bodvarsson, M.; Arnadottir, M.; Redden, D.; Mutwali, A.; Griffin, B.; Lenihan, C.; O'Seaghda, C.; Lappin, D.; Gafney, M.; Akram, M.; Marchesi, D.; Mingardi, G.; Allaria, P.; Giangrande, A.; Lucatello, A.; Caligara, F.; Angelo, L.; Deferrari, G.; Robaudo, C.; Lauria, F.; Imbasciati, E.; Barbisoni, F.; Farina, M.; Maggio, M.; Borlandelli, S.; Badalamenti, S.; Finazzi, S.; Angelini, C.; Bianchi, G.; Spotti, D.; Quartagno, R.; Malberti, F.; La Russa, A.; Pecchini, P.; Ghiringhelli, P.; Zoccali, C.; Delfino, D.; Mallamaci, F.; Marino, F.; Curatola, G.; Caridi, G.; Ciccarelli, M.; Borghi, M.; Tagliaferri, M.; Massazza, M.; Espinoza, B.; Torres, M.; López, E.; Montañez, J. L.; Bochicchio, T.; Cruz, J.; Cordero, L.; Hollander, A.; Hoogeveen, E.; Koolen, M.; Bos, W.; Endeman, H.; Vincent, H.; Geers, T.; Rensma, P.; Apperloo, A.; Haest, R.; van de Ven, P.; Alphen, R.; van Buren, M.; Essen, G.; Woittiez, A.; Ouwehand, A.; Vleming, L.; Krol-van Stratten, M.; Janssen, W.; Kremer Horinga, T.; Kloppenburg, W.; Doorenbos, C.; Sluiter, H.; Smak-Gregoor, P.; van Bommel, E.; Jongh, J.; Verseput, G.; Hagen, E.; Stork, A.; Gaillard, C.; Pondman, M.; Bax, W.; van Geelen, J.; Schrama, Y.; Rietveld, A.; Op de Hoek, C.; Diderich, P.; Kaasjager, H.; Bosch, F.; Reichert, L.; Hemmelder, M.; Halma, C.; Broekroelofs, J.; Haanstra, W.; Vastenburg, G.; de Fijter, C.; Groeneveld, J.; Bergrem, H.; Thorud, L.; Viko, H.; Eggesbø, J.; Halvorsen, C.; Hunderi, O.; Abedini, S.; Broch, L.; Heldal, K.; Lyngdal, P.; Iversen, B.; Øien, C.; Selvig, K.; Witkowicz, J.; Spiechowicz-Zatoń, U.; Marcinkowski, W.; Ksiazek, A.; Baranowicz-Gaszczyk, I.; Jóźwiak, L.; Kuczera, M.; Szweblik, J.; Bieńkowski, J.; Wajda, J.; Bogdanowicz, G.; Jaworska-Wieczorek, J.; Myśliwiec, M.; Barczyk, M.; Kalinowski, M.; Mazerska, M.; Trusewicz, W.; Ostrowski, J.; Błaszczyk, E.; Majczyńska, I.; Kazimierczak, J.; Kacki, J.; Kochman, P.; Rutkowski, B.; Białobrzeska, B.; Jankowska, M.; Chmielewski, M.; Zdrojewski, Z.; Debska-Slizień, A.; Switalski, M.; Kepka, A.; Szewczyk, D.; Fusik, J.; Kuriga, M.; Ostrowski, M.; Myszta, T.; Sułowicz, W.; Radziszewski, A.; Walatek, B.; Kaczmarczyk, I.; Drozdz, M.; Piotrowska, M.; Kraśnicka, M.; Koźmiński, P.; Pawłowska, S.; Zygadło, H.; Zalasińska, I.; Chae, D.-W.; Jin, H.; Kim, S.; Song, Y.; Na, K.-Y.; Oh, J.-E.; Oh, K. H.; Kim, Y.-G.; Kim, B.; Baek, H.-J.; Kim, J.-A.; Lee, Y. J.; Chang, Y.-S.; Park, C. W.; Chung, H.-W.; Han, S.; Kim, Y.-S.; Park, J.-A.; Choi, B.-S.; Yoon, H. E.; Hwang, H.; Yoon, J.-M.; Kim, J.-Y.; Han, S.-W.; Kang, C.-M.; Lee, C.-W.; Kim, G.-H.; Choi, N.-W.; Ihm, C.-G.; Jeong, K.-H.; Kim, M.-J.; Lee, S.-H.; Lee, T.-W.; Wikström, B.; Linde, T.; Nisbeth, U.; Mulec, H.; Kronvall, M.; Frisenette-Fich, C.; Ståhl Nilsson, A.; Mauritz, N.-J.; Schirdewan, S.; Stelin, G.; Ottosson, P.; Stefansson, B.; Ramsauer, B.; Hultström, D.; Hadimeri, H.; Andersson, P.-O.; Al Magdasi, H.; Weiss, L.; Welander, G.; Gröntoft, K. C.; Zezina, L.; Svensson, L.; Fagerström, A.; Lund, U.; Tidman, M.; Lundin, C.; Sjöström, P.; Wessén, P.; Halvarsson, P.; Wrege, U.; Linder, M.; Ekspong, A.; Jensen, G.; Alfredsson, A.; Löfberg, E.; Almroth, G.; Haarhaus, M.; Gisslén, K.; Mathillas, O.; Bock, A.; Burnier, M.; Binet, I.; Tsinalis, D.; Wüthrich, R.; Basci, A.; Turgan, C.; Duranay, M.; Nergizoglu, G.; Gullulu, M.; Turkmen, F.

    2009-01-01

    BACKGROUND: Statins reduce the incidence of cardiovascular events in patients at high cardiovascular risk. However, a benefit of statins in such patients who are undergoing hemodialysis has not been proved. METHODS: We conducted an international, multicenter, randomized, double-blind, prospective

  14. Coping strategies used by hospitalized children with cancer undergoing chemotherapy.

    Science.gov (United States)

    Sposito, Amanda Mota Pacciulio; Silva-Rodrigues, Fernanda Machado; Sparapani, Valéria de Cássia; Pfeifer, Luzia Iara; de Lima, Regina Aparecida Garcia; Nascimento, Lucila Castanheira

    2015-03-01

    To analyze coping strategies used by children with cancer undergoing chemotherapy during hospitalization. This was an exploratory study to analyze qualitative data using an inductive thematic analysis. Semistructured interviews using puppets were conducted with 10 children with cancer, between 7 and 12 years old, who were hospitalized and undergoing chemotherapy. The coping strategies to deal with chemotherapy were: understanding the need for chemotherapy; finding relief for the chemotherapy's side effects and pain; seeking pleasure in nourishment; engaging in entertaining activities and having fun; keeping the hope of cure alive; and finding support in religion. Children with cancer undergoing chemotherapy need to cope with hospitalizations, pain, medication side effects, idle time, and uncertainty regarding the success of treatment. These challenges motivated children to develop their own coping strategies, which were effective while undergoing chemotherapy. By gaining knowledge and further understanding about valid coping strategies during chemotherapy treatment, health professionals can mobilize personal and material resources from the children, health teams, and institutions aiming to potentiate the use of these strategies to make treatments the least traumatic. © 2015 Sigma Theta Tau International.

  15. Preoperative B-type natriuretic peptides in patients undergoing ...

    African Journals Online (AJOL)

    Preoperative B-type natriuretic peptides in patients undergoing noncardiac surgery: a cumulative meta-analysis. ... Journal Home > Vol 21, No 4 (2015) > ... Future investigation should focus on the clinical implications of these data and the application of these findings with regard to further investigation, optimisation and ...

  16. 76 FR 78925 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-12-20

    ... the use of corticosteroids and control of exposure to allergens and irritants, collectively known as... HUMAN SERVICES Centers for Disease Control and Prevention Agency Forms Undergoing Paperwork Reduction Act Review The Centers for Disease Control and Prevention (CDC) publishes a list of information...

  17. Astronaut James Lovell undergoes weight and balance tests

    Science.gov (United States)

    1965-01-01

    Astronaut James A. Lovell Jr., pilot of the Gemini 7 space flight, undergoes weight and balance tests in the Pyrotechnic installation Building, Merritt Island. Talking with Lovell are (left to right) Charlie Beaty, McDonnell Aircraft Corporation; Karl Stoien, McDonnell Aircraft; NASA suit technician Al Rochford; and Norm Batterson, Weber Aircraft Corporation.

  18. 78 FR 4149 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2013-01-18

    ... who is in the communicable period for cholera, plague, smallpox, typhus, or yellow fever or having... HUMAN SERVICES Centers for Disease Control and Prevention Agency Forms Undergoing Paperwork Reduction Act Review The Centers for Disease Control and Prevention (CDC) publishes a list of information...

  19. 75 FR 6670 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2010-02-10

    ..., smallpox, typhus, or yellow fever or having been exposed to any such disease is in the incubation period... HUMAN SERVICES Centers for Disease Control and Prevention Agency Forms Undergoing Paperwork Reduction Act Review The Centers for Disease Control and Prevention (CDC) publishes a list of information...

  20. 77 FR 38065 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2012-06-26

    ... HUMAN SERVICES Centers for Disease Control and Prevention Agency Forms Undergoing Paperwork Reduction... neural tube defects, and can include hearing or vision loss, mental retardation, psychomotor delays, and... collection activities will consist of two phases of research: Phase I will consist of focus groups and Phase...

  1. 76 FR 18553 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-04-04

    ... HUMAN SERVICES Centers for Disease Control and Prevention Agency Forms Undergoing Paperwork Reduction... of Effective Behavioral Interventions (EBIs) for HIV prevention. Women Involved in Life Learning from Other Women (WILLOW) is an EBI that focuses on health education and social skills building among women...

  2. 76 FR 29243 - Agency Forms Undergoing Paperwork Reduction Act Review

    Science.gov (United States)

    2011-05-20

    ... control measures with respect to conveyances (e.g., airplanes, cruise ships), persons, and shipments of... HUMAN SERVICES Centers for Disease Control and Prevention Agency Forms Undergoing Paperwork Reduction Act Review The Centers for Disease Control and Prevention (CDC) publishes a list of information...

  3. Simultaneous Velocity and Vorticity Measurement in Turbulence

    Science.gov (United States)

    Wu, Huixuan; Xu, Haitao; Bodenschatz, Eberhard

    2013-11-01

    A new paradigm of simultaneous velocity and vorticity measurement is developed to study turbulence. Instead of deducing vorticity from velocities measured at neighboring points, this innovative approach detects the translations and rotations of micro-sized particles directly. These hydrogel particles are spherical, transparent, and encapsulate micro-mirrors. This method outstands conventional ones, e.g., hotwire arrays or PIV because its spatial resolution is much higher. It does not require a non-zero mean flow, and it can provide all three vorticity components, which is not available from planar PIV data. Its principle is to illuminate the mirror and utilize the variation of the reflection directions to deduce the local flow vorticity. Meanwhile, the particle position is recorded as in normal particle tracking. Therefore, the velocity and vorticity of a particle can be obtained simultaneously in Lagrangian framework. The authors have made benchmark experiments to evaluate this novel method in Taylor Couette flows. The results show that the instantaneous vorticity measurement is as accurate as 3%. We are now setting up a von Karman disk pair device to study the turbulent flow. This novel technique will provide unprecedented information of high Reynolds number turbulence. The first author thanks the Alexander von Humboldt Foundation.

  4. Simultaneous structure and texture image inpainting.

    Science.gov (United States)

    Bertalmio, Marcelo; Vese, Luminita; Sapiro, Guillermo; Osher, Stanley

    2003-01-01

    An algorithm for the simultaneous filling-in of texture and structure in regions of missing image information is presented in this paper. The basic idea is to first decompose the image into the sum of two functions with different basic characteristics, and then reconstruct each one of these functions separately with structure and texture filling-in algorithms. The first function used in the decomposition is of bounded variation, representing the underlying image structure, while the second function captures the texture and possible noise. The region of missing information in the bounded variation image is reconstructed using image inpainting algorithms, while the same region in the texture image is filled-in with texture synthesis techniques. The original image is then reconstructed adding back these two sub-images. The novel contribution of this paper is then in the combination of these three previously developed components, image decomposition with inpainting and texture synthesis, which permits the simultaneous use of filling-in algorithms that are suited for different image characteristics. Examples on real images show the advantages of this proposed approach.

  5. Simultaneous optiimisation of nutritional quality and environmental sustainability of diets

    NARCIS (Netherlands)

    van Dooren, C.

    2018-01-01

    Simultaneous optimisation of the nutritional quality and environmental sustainability of diets The purpose of this thesis was to explore how the nutritional quality and environmental sustainability of diets can be optimised simultaneously. This work operationalised and quantified the concept of

  6. Simultaneous mass balance inverse modeling of methane and carbon monoxide

    Science.gov (United States)

    Butler, T. M.; Rayner, P. J.; Simmonds, I.; Lawrence, M. G.

    2005-11-01

    We perform a simultaneous mass-balance inversion of atmospheric methane (CH4) and carbon monoxide (CO) using measurements from the NOAA/CMDL Cooperative Air Sampling Network and a model of tropospheric transport and background chemistry over the period 1990-2000. Our method has a spatial resolution of a semihemisphere and a temporal resolution of 1 month. The deduced CO sources show relatively low interannual variability except around the major biomass burning event in 1997-1998, when we calculate an anomalous emission between July 1997 and December 1998 of 270 Tg(CO). This is enough to suppress the modeled global air mass weighted hydroxyl radical (OH) concentration during this time by 2.2%, and account for 75% of the observed increase in CH4 mixing ratios during 1998. We compare our implied CH4/CO emissions factors with published biomass burning emissions factors, suggesting that the remainder of the increase in CH4 observed in 1998 is due to anomalously high biomass burning emissions, with CH4 emissions from wetlands showing a small negative anomaly in 1998.

  7. Simultaneous prediction of protein secondary structure and transmembrane spans.

    Science.gov (United States)

    Leman, Julia Koehler; Mueller, Ralf; Karakas, Mert; Woetzel, Nils; Meiler, Jens

    2013-07-01

    Prediction of transmembrane spans and secondary structure from the protein sequence is generally the first step in the structural characterization of (membrane) proteins. Preference of a stretch of amino acids in a protein to form secondary structure and being placed in the membrane are correlated. Nevertheless, current methods predict either secondary structure or individual transmembrane states. We introduce a method that simultaneously predicts the secondary structure and transmembrane spans from the protein sequence. This approach not only eliminates the necessity to create a consensus prediction from possibly contradicting outputs of several predictors but bears the potential to predict conformational switches, i.e., sequence regions that have a high probability to change for example from a coil conformation in solution to an α-helical transmembrane state. An artificial neural network was trained on databases of 177 membrane proteins and 6048 soluble proteins. The output is a 3 × 3 dimensional probability matrix for each residue in the sequence that combines three secondary structure types (helix, strand, coil) and three environment types (membrane core, interface, solution). The prediction accuracies are 70.3% for nine possible states, 73.2% for three-state secondary structure prediction, and 94.8% for three-state transmembrane span prediction. These accuracies are comparable to state-of-the-art predictors of secondary structure (e.g., Psipred) or transmembrane placement (e.g., OCTOPUS). The method is available as web server and for download at www.meilerlab.org. Copyright © 2013 Wiley Periodicals, Inc.

  8. Managing Networks

    DEFF Research Database (Denmark)

    Jørgensen, Heidi; Vintergaard, Christian

    Logically it seems that companies pursuing different business strategies wouldalso manage their relationships with other firms accordingly. Nevertheless, due tothe lack of research in the field of network strategies, this link still remainsinadequately examined. Based on the well-known framework...... isprovided, that the relation between a company's strategy, structure and processesin fact have a considerable influence on its pattern of network behaviour. Threecase studies from the Danish biotech industry exemplify and illustrate how acompany's strategy is directly correlated with how it manages its...... of organisationalbehaviour developed by Miles and Snow (1978), this paper argues that thepatterns of network behaviour practiced by firms greatly depend on the businesstypology of the company. That is, a company's business typology will to a certaindegree dictate the network identity of the company. In this paper evidence...

  9. Heterodox networks

    DEFF Research Database (Denmark)

    Lala, Purnima; Kumar, Ambuj

    2016-01-01

    architecture of ‘Hovering Ad-hoc Network (HANET)’ for the latter will be deployed to assist and manage the overloaded primary base stations enhancing the on-demand coverage and capacity of the entire system. Proposed modes can either operate independently or as a cascaded architecture to form a Heterodox......It is imperative for the service providers to bring innovation in the network design to meet the exponential growth of mobile subscribers for multi-technology future wireless networks. As a matter of research, studies on providing services to moving subscriber groups aka ‘Place Time Capacity (PTC......)’ have not been considered much in the literature. In this article we present Heterodox networks as an innovative and alternate approach to handle the PTC congestion. We describe two different approaches to combat the PTC congestion where the traditional terrestrial infrastructure fails to provide...

  10. Exchange Network

    Science.gov (United States)

    The Environmental Information Exchange Network (EIEN) is an Internet-based system used by state, tribal and territorial partners to securely share environmental and health information with one another and EPA.

  11. Sentinel Network

    Science.gov (United States)

    The Sentinel Network is an integrated, electronic, national medical product safety initiative that compiles information about the safe and effective use of medical products accessible to patients and healthcare practitioners.

  12. computer networks

    Directory of Open Access Journals (Sweden)

    N. U. Ahmed

    2002-01-01

    Full Text Available In this paper, we construct a new dynamic model for the Token Bucket (TB algorithm used in computer networks and use systems approach for its analysis. This model is then augmented by adding a dynamic model for a multiplexor at an access node where the TB exercises a policing function. In the model, traffic policing, multiplexing and network utilization are formally defined. Based on the model, we study such issues as (quality of service QoS, traffic sizing and network dimensioning. Also we propose an algorithm using feedback control to improve QoS and network utilization. Applying MPEG video traces as the input traffic to the model, we verify the usefulness and effectiveness of our model.

  13. Affective Networks

    Directory of Open Access Journals (Sweden)

    Jodi Dean

    2010-02-01

    Full Text Available This article sets out the idea of affective networks as a constitutive feature of communicative capitalism. It explores the circulation of intensities in contemporary information and communication networks, arguing that this circulation should be theorized in terms of the psychoanalytic notion of the drive. The article includes critical engagements with theorists such as Guy Debord, Jacques Lacan, Tiziana Terranova, and Slavoj Zizek.

  14. Friendship Networks

    OpenAIRE

    Jan K. Brueckner

    2004-01-01

    Building upon a long tradition in sociology, economists have recently turned their attention to the analysis of social networks. The present paper adds to this emerging literature by proposing a different approach to social-network formation. As in the model of Jackson and Wolinsky (1996), formation of a link between two individuals requires two-sided investments in the present framework. But in contrast to their approach, where the required investments are exogenously specified and link form...

  15. Developer Network

    Energy Technology Data Exchange (ETDEWEB)

    2012-08-21

    NREL's Developer Network, developer.nrel.gov, provides data that users can access to provide data to their own analyses, mobile and web applications. Developers can retrieve the data through a Web services API (application programming interface). The Developer Network handles overhead of serving up web services such as key management, authentication, analytics, reporting, documentation standards, and throttling in a common architecture, while allowing web services and APIs to be maintained and managed independently.

  16. Transport Protocols for Wireless Mesh Networks

    Science.gov (United States)

    Eddie Law, K. L.

    Transmission control protocol (TCP) provides reliable connection-oriented services between any two end systems on the Internet. With TCP congestion control algorithm, multiple TCP connections can share network and link resources simultaneously. These TCP congestion control mechanisms have been operating effectively in wired networks. However, performance of TCP connections degrades rapidly in wireless and lossy networks. To sustain the throughput performance of TCP connections in wireless networks, design modifications may be required accordingly in the TCP flow control algorithm, and potentially, in association with other protocols in other layers for proper adaptations. In this chapter, we explain the limitations of the latest TCP congestion control algorithm, and then review some popular designs for TCP connections to operate effectively in wireless mesh network infrastructure.

  17. Network Power Fault Detection

    OpenAIRE

    Siviero, Claudio

    2013-01-01

    Network power fault detection. At least one first network device is instructed to temporarily disconnect from a power supply path of a network, and at least one characteristic of the power supply path of the network is measured at a second network device connected to the network while the at least one first network device is temporarily disconnected from the network

  18. Complex Networks

    CERN Document Server

    Evsukoff, Alexandre; González, Marta

    2013-01-01

    In the last decade we have seen the emergence of a new inter-disciplinary field focusing on the understanding of networks which are dynamic, large, open, and have a structure sometimes called random-biased. The field of Complex Networks is helping us better understand many complex phenomena such as the spread of  deseases, protein interactions, social relationships, to name but a few. Studies in Complex Networks are gaining attention due to some major scientific breakthroughs proposed by network scientists helping us understand and model interactions contained in large datasets. In fact, if we could point to one event leading to the widespread use of complex network analysis is the availability of online databases. Theories of Random Graphs from Erdös and Rényi from the late 1950s led us to believe that most networks had random characteristics. The work on large online datasets told us otherwise. Starting with the work of Barabási and Albert as well as Watts and Strogatz in the late 1990s, we now know th...

  19. Sentient networks

    Energy Technology Data Exchange (ETDEWEB)

    Chapline, G.

    1998-03-01

    The engineering problems of constructing autonomous networks of sensors and data processors that can provide alerts for dangerous situations provide a new context for debating the question whether man-made systems can emulate the cognitive capabilities of the mammalian brain. In this paper we consider the question whether a distributed network of sensors and data processors can form ``perceptions`` based on sensory data. Because sensory data can have exponentially many explanations, the use of a central data processor to analyze the outputs from a large ensemble of sensors will in general introduce unacceptable latencies for responding to dangerous situations. A better idea is to use a distributed ``Helmholtz machine`` architecture in which the sensors are connected to a network of simple processors, and the collective state of the network as a whole provides an explanation for the sensory data. In general communication within such a network will require time division multiplexing, which opens the door to the possibility that with certain refinements to the Helmholtz machine architecture it may be possible to build sensor networks that exhibit a form of artificial consciousness.

  20. Quality of sleep in patients undergoing cardiac surgery during the postoperative period in intensive care.

    Science.gov (United States)

    Navarro-García, M Á; de Carlos Alegre, V; Martinez-Oroz, A; Irigoyen-Aristorena, M I; Elizondo-Sotro, A; Indurain-Fernández, S; Martorell-Gurucharri, A; Sorbet-Amóstegui, M R; Prieto-Guembe, P; Ordoñez-Ortigosa, E; García-Aizpún, Y; García-Ganuza, R

    To describe the quality of sleep of patients undergoing cardiac surgery during the first two nights following surgery and identify some of the factors conditioning the nightly rest of these patients in the Intensive Care Unit. Observational descriptive study based on applying the Richards-Campbell Sleep Questionnaire through a consecutive sample of patients undergoing cardiac surgery with Intensive Care Unit admission. Simultaneously, a questionnaire assessing different environmental factors existing in the unit as possible conditioning of the night's rest was applied. The association between consumption of opioid and sleep quality was studied. Sample of 66 patients with a mean age of 65±11.57 years, of which 73% were men (N=48). The Richards-Campbell sleep questionnaire garnered average scores of 50.33mm (1.st night) and 53.30mm (2.nd night). The main sleep disturbing factors were discomfort with the different devices, 30.91mm and pain, 30.18mm. The problems caused by environmental noise, 27.5mm or through the voices of the professionals, 26.53mm were also elements of nocturnal discomfort. No statistical association was found between sleep and the distance of the patient with respect to the nursing control area or related to opioid analgesics. The quality of sleep during the first two nights of Intensive Care Unit admission was "regular". The environmental factors that conditioned the night-time rest of patients were discomfort, pain and ambient noise. Copyright © 2016 Sociedad Española de Enfermería Intensiva y Unidades Coronarias (SEEIUC). Publicado por Elsevier España, S.L.U. All rights reserved.

  1. Characteristics and clinical aspects of patients with spinal cord injury undergoing surgery

    Directory of Open Access Journals (Sweden)

    João Simão de Melo-Neto

    Full Text Available ABSTRACT OBJECTIVE: To identify the characteristics of patients with spinal cord injury (SCI undergoing surgery. METHODS: Previously, 321 patients with SCI were selected. Clinical and socio-demographic variables were collected. RESULTS: A total of 211 patients were submitted to surgery. Fall and injuries in the upper cervical and lumbosacral regions were associated with conservative treatment. Patients with lesions in the lower cervical spine, worse neurological status, and unstable injuries were associated with surgery. Individuals undergoing surgery were associated with complications after treatment. The authors assessed whether age influenced the characteristics of patients submitted to surgery. Subjects with <60 years of age were associated with motorcycle accidents and the morphologies of injury were fracture-dislocation. Elderly individuals were associated to fall, SCI in the lower cervical spine and the morphology of injury was listhesis. Subsequently, the authors analyzed the gender characteristics in these patients. Women who suffered car accidents were associated to surgery. Women were associated with paraparesis and the morphologic diagnosis was fracture-explosion, especially in the thoracolumbar transition and lumbosacral regions. Men who presented traumatic brain injury and thoracic trauma were related to surgery. These individuals had a worse neurological status and were associated to complications. Men and the cervical region were most affected, thereby, these subjects were analyzed separately (n= 92. The presence of complications increased the length of hospital stay. The simultaneous presence of morphological diagnosis, worst neurological status, tetraplegia, sensory, and motor alterations were associated with complications. Pneumonia and chest trauma were associated with mortality. CONCLUSION: These factors enable investments in prevention, rehabilitation, and treatment.

  2. THE PREVALENCE & TREATMENT OF DEPRESSION IN PATIENTS UNDERGOING HAEMODIALYSIS IN A TERTIARY CARE CENTRE

    Directory of Open Access Journals (Sweden)

    Vinod V. S

    2016-06-01

    Full Text Available BACKGROUND Psychiatric illness like depression is common in chronic kidney disease patients. With this rising incidence of chronic kidney disease in Kerala, we need to determine the extent of problem and find appropriate strategy to manage these cases. The purpose of this study was to find out the prevalence of depression in chronic kidney disease patients undergoing haemodialysis, the proportion of patients getting treatment for depression, various factors influencing the prevalence of depression in the dialysis group and also to find out a bedside tool for assessing the prevalence of depression which can be used by the treating physician as well. METHODS This is a cross-sectional observational prospective study conducted among 50 patients aged above 18 years undergoing haemodialysis. All underwent screening using Beck’s Depression Inventory Scale II and were simultaneously assessed for depression and confirmed by using diagnostic and statistical manual for mental disorders IV criteria, with the help of a psychiatrist. STATISTICS ANALYSIS Chi square test was applied to know the association between two categorical variables. Statistical significance was set at P<0.05. RESULTS Out of 50 patients, 23 were found to have depression using Beck’s Depression inventory scale II as well as diagnostic and statistical manual for mental disorders IV criteria. Out of the 23 patients diagnosed to have depression with Beck’s Depression inventory scale II, only 3 patients (13% were getting treatments for depression. Also depression was associated with hypoalbuminaemia, anaemia, hyponatraemia and hypocalcaemia. CONCLUSION Beck’s Depression Inventory scale was showing good correlation with diagnostic and statistical manual for mental disorders IV criteria diagnosis of depression and hence, it may also be used for screening depression, by the treating physician.

  3. Central nervous system gadolinium accumulation in patients undergoing periodical contrast MRI screening for hereditary tumor syndromes.

    Science.gov (United States)

    Vergauwen, Evelynn; Vanbinst, Anne-Marie; Brussaard, Carola; Janssens, Peter; De Clerck, Dieter; Van Lint, Michel; Houtman, Anne C; Michel, Olaf; Keymolen, Kathelijn; Lefevere, Bieke; Bohler, Susanne; Michielsen, Dirk; Jansen, Anna C; Van Velthoven, Vera; Gläsker, Sven

    2018-01-01

    Patients with hereditary tumor syndromes undergo periodical magnetic resonance imaging (MRI) screening with Gadolinium contrast. Gadolinium accumulation has recently been described in the central nervous system after repeated administrations. The prevalence and rate of accumulation in different subgroups of patients are unknown. Neither are the mechanism nor clinical impact. This may cause uncertainty about the screening. To explore the prevalence and rate of Gadolinium accumulation in different subgroups, we retrospectively analyzed MRIs of patients with von Hippel-Lindau disease (VHL) and Tuberous Sclerosis Complex (TSC). We determined the prevalence and rate of accumulation in the dentate nucleus and globus pallidus on unenhanced T1-weighted MRI from VHL and TSC patients. We compared the signal intensities of these regions to the signal intensity of the pons. We evaluated the impact of number of MRIs, kidney function and liver function on Gadolinium accumulation. Twenty eight VHL patients and 24 TSC patients were included. The prevalence of accumulation in the dentate nucleus and globus pallidus increased linearly according to number of Gadolinium enhanced MRIs and was higher in the VHL group (100%). A significant linear correlation between number of MRIs and increased signal intensity was observed in the VHL group. Gadolinium accumulation occurs in almost all patients undergoing contrast MRI screening after >5 MRIs. We advocate a screening protocol for patients with hereditary tumor syndromes that minimizes the Gadolinium dose. This can be accomplished by using a single administration to simultaneously screen for brain, spine and/or abdominal lesions, using an MRI protocol focused on either VHL- or TSC-specific lesions. Higher prevalence and rate of accumulation in VHL patients may be explained by the typical vascular leakage accompanying central nervous system hemangioblastomas.

  4. Information transfer network of global market indices

    Science.gov (United States)

    Kim, Yup; Kim, Jinho; Yook, Soon-Hyung

    2015-07-01

    We study the topological properties of the information transfer networks (ITN) of the global financial market indices for six different periods. ITN is a directed weighted network, in which the direction and weight are determined by the transfer entropy between market indices. By applying the threshold method, it is found that ITN undergoes a crossover from the complete graph to a small-world (SW) network. SW regime of ITN for a global crisis is found to be much more enhanced than that for ordinary periods. Furthermore, when ITN is in SW regime, the average clustering coefficient is found to be synchronized with average volatility of markets. We also compare the results with the topological properties of correlation networks.

  5. Relaxation dynamics of maximally clustered networks

    Science.gov (United States)

    Klaise, Janis; Johnson, Samuel

    2018-01-01

    We study the relaxation dynamics of fully clustered networks (maximal number of triangles) to an unclustered state under two different edge dynamics—the double-edge swap, corresponding to degree-preserving randomization of the configuration model, and single edge replacement, corresponding to full randomization of the Erdős-Rényi random graph. We derive expressions for the time evolution of the degree distribution, edge multiplicity distribution and clustering coefficient. We show that under both dynamics networks undergo a continuous phase transition in which a giant connected component is formed. We calculate the position of the phase transition analytically using the Erdős-Rényi phenomenology.

  6. Global Optimization for Transport Network Expansion and Signal Setting

    Directory of Open Access Journals (Sweden)

    Haoxiang Liu

    2015-01-01

    Full Text Available This paper proposes a model to address an urban transport planning problem involving combined network design and signal setting in a saturated network. Conventional transport planning models usually deal with the network design problem and signal setting problem separately. However, the fact that network capacity design and capacity allocation determined by network signal setting combine to govern the transport network performance requires the optimal transport planning to consider the two problems simultaneously. In this study, a combined network capacity expansion and signal setting model with consideration of vehicle queuing on approaching legs of intersection is developed to consider their mutual interactions so that best transport network performance can be guaranteed. We formulate the model as a bilevel program and design an approximated global optimization solution method based on mixed-integer linearization approach to solve the problem, which is inherently nnonlinear and nonconvex. Numerical experiments are conducted to demonstrate the model application and the efficiency of solution algorithm.

  7. Autonomous vision networking: miniature wireless sensor networks with imaging technology

    Science.gov (United States)

    Messinger, Gioia; Goldberg, Giora

    2006-09-01

    . Image processing at the sensor node level may also be required for applications in security, asset management and process control. Due to the data bandwidth requirements posed on the network by video sensors, new networking protocols or video extensions to existing standards (e.g. Zigbee) are required. To this end, Avaak has designed and implemented an ultra-low power networking protocol designed to carry large volumes of data through the network. The low power wireless sensor nodes that will be discussed include a chemical sensor integrated with a CMOS digital camera, a controller, a DSP processor and a radio communication transceiver, which enables relaying of an alarm or image message, to a central station. In addition to the communications, identification is very desirable; hence location awareness will be later incorporated to the system in the form of Time-Of-Arrival triangulation, via wide band signaling. While the wireless imaging kernel already exists specific applications for surveillance and chemical detection are under development by Avaak, as part of a co-founded program from ONR and DARPA. Avaak is also designing vision networks for commercial applications - some of which are undergoing initial field tests.

  8. Simultaneous liver-kidney versus liver transplantation alone in patients with end-stage liver disease and kidney dysfunction not on dialysis.

    Science.gov (United States)

    Mindikoglu, A L; Raufman, J P; Seliger, S L; Howell, C D; Magder, L S

    2011-09-01

    Since implementation of the Model for End-stage Liver Disease (MELD), the number of simultaneous liver-kidney transplantations (SLKT) has increased in the United States. However, predictors and survival benefit of SLKT compared to liver transplantation alone (LTA) are not well defined. Organ Procurement and Transplantation Network data of patients with end-stage liver disease (ESLD) with estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m(2) who had not been on dialysis while on the waiting list and underwent liver transplantation between 2002 and 2008 were analyzed. To identify predictors of undergoing SLKT versus LTA, multiple logistic regression analysis was performed. Cox proportional hazards regression analysis was used to assess the association between SLKT and post-liver transplant patient and graft survival. The study cohort comprised 5443 patients; 262 (5%) underwent SLKT and 5181 (95%) underwent LTA. Adjusting for potential confounders, patients who underwent SLKT were 34% less likely to die after liver transplantation than those who underwent LTA (hazard ratio [HR] = 0.66, P = .012) and 33% less likely to have liver graft failure than those who underwent LTA (HR = 0.67, P = .010). Among those who underwent SLKT, 1-, 3-, and 5-year kidney graft survival probabilities were 88%, 80%, and 77%, respectively. Black race and diabetes were associated with a higher likelihood of SLKT versus LTA; female sex, a higher eGFR, and higher MELD score reduced the likelihood of SLKT. Among those with ESLD and kidney dysfunction not on dialysis, post-liver transplant patient and liver graft survivals of patients who underwent SLKT were superior to those of patients who underwent LTA. Whether this reflects differences in the two groups that could not be adjusted in survival models or a specific effect of kidney dysfunction cannot be established. Copyright © 2011 Elsevier Inc. All rights reserved.

  9. Evaluation of a transient, simultaneous, arbitrary Lagrange-Euler based multi-physics method for simulating the mitral heart valve.

    Science.gov (United States)

    Espino, Daniel M; Shepherd, Duncan E T; Hukins, David W L

    2014-01-01

    A transient multi-physics model of the mitral heart valve has been developed, which allows simultaneous calculation of fluid flow and structural deformation. A recently developed contact method has been applied to enable simulation of systole (the stage when blood pressure is elevated within the heart to pump blood to the body). The geometry was simplified to represent the mitral valve within the heart walls in two dimensions. Only the mitral valve undergoes deformation. A moving arbitrary Lagrange-Euler mesh is used to allow true fluid-structure interaction (FSI). The FSI model requires blood flow to induce valve closure by inducing strains in the region of 10-20%. Model predictions were found to be consistent with existing literature and will undergo further development.

  10. Canonical correlation between LFP network and spike network during working memory task in rat.

    Science.gov (United States)

    Yi, Hu; Zhang, Xiaofan; Bai, Wenwen; Liu, Tiaotiao; Tian, Xin

    2015-08-01

    Working memory refers to a system to temporary holding and manipulation of information. Previous studies suggested that local field potentials (LFPs) and spikes as well as their coordination provide potential mechanism of working memory. Popular methods for LFP-spike coordination only focus on the two modality signals, isolating each channel from multi-channel data, ignoring the entirety of the networked brain. Therefore, we investigated the coordination between the LFP network and spike network to achieve a better understanding of working memory. Multi-channel LFPs and spikes were simultaneously recorded in rat prefrontal cortex via microelectrode array during a Y-maze working memory task. Functional connectivity in the LFP network and spike network was respectively estimated by the directed transfer function (DTF) and maximum likelihood estimation (MLE). Then the coordination between the two networks was quantified via canonical correlation analysis (CCA). The results show that the canonical correlation (CC) varied during the working memory task. The CC-curve peaked before the choice point, describing the coordination between LFP network and spike network enhanced greatly. The CC value in working memory showed a significant higher level than inter-trial interval. Our results indicate that the enhanced canonical correlation between the LFP network and spike network may provide a potential network integration mechanism for working memory. Copyright © 2015 Elsevier B.V. All rights reserved.

  11. Simultaneous covalent and noncovalent hybrid polymerizations

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Zhilin; Tantakitti, Faifan; Yu, Tao; Palmer, Liam C.; Schatz, George C.; Stupp, Samuel I. (NWU)

    2016-01-28

    Covalent and supramolecular polymers are two distinct forms of soft matter, composed of long chains of covalently and noncovalently linked structural units, respectively. We report a hybrid system formed by simultaneous covalent and supramolecular polymerizations of monomers. The process yields cylindrical fibers of uniform diameter that contain covalent and supramolecular compartments, a morphology not observed when the two polymers are formed independently. The covalent polymer has a rigid aromatic imine backbone with helicoidal conformation, and its alkylated peptide side chains are structurally identical to the monomer molecules of supramolecular polymers. In the hybrid system, covalent chains grow to higher average molar mass relative to chains formed via the same polymerization in the absence of a supramolecular compartment. The supramolecular compartments can be reversibly removed and re-formed to reconstitute the hybrid structure, suggesting soft materials with novel delivery or repair functions.

  12. Humanization and simultaneous optimization of monoclonal antibody.

    Science.gov (United States)

    Kuramochi, T; Igawa, T; Tsunoda, H; Hattori, K

    2014-01-01

    Antibody humanization is an essential technology for reducing the potential risk of immunogenicity associated with animal-derived antibodies and has been applied to a majority of the therapeutic antibodies on the market. For developing an antibody molecule as a pharmaceutical at the current biotechnology level, however, other properties also have to be considered in parallel with humanization in antibody generation and optimization. This section describes the critical properties of therapeutic antibodies that should be sufficiently qualified, including immunogenicity, binding affinity, physiochemical stability, expression in host cells and pharmacokinetics, and the basic methodologies of antibody engineering involved. By simultaneously optimizing the antibody molecule in the light of these properties, it should prove possible to shorten the research and development period necessary to identify a highly qualified clinical candidate and consequently accelerate the start of the clinical trial.

  13. Simultaneous bilateral patellar tendon rupture without

    Directory of Open Access Journals (Sweden)

    LU Hua-ding

    2012-04-01

    Full Text Available 【Abstract】There is a dearth of case reports de-scribing simultaneous bilateral patellar tendon ruptures in the medical literature. These ruptures are often associated with systemic disorders such as lupus erythematosus or chronic steroid use. The author describes a case of a 24-year-old man who sustained traumatic bilateral patellar ten-don ruptures without any history of systemic disease or steroidal medication. We repaired and reattached the rup-tured tendons to the patella and augmented our procedure with allogeneic tendon followed by wire loop reinforcement. One year after operation, the patient regained a satisfactory range of motion of both knees with good quadriceps strength and no extensor lag. The recurrent microtrauma from a history of intense sports activity and a high body mass index may have played an important role in this trauma event. Key words: Patella; Patellar ligament; Rupture; Ten-don injuries; Knee

  14. Simultaneous determination of protein structure and dynamics

    DEFF Research Database (Denmark)

    Lindorff-Larsen, Kresten; Best, Robert B.; DePristo, M. A.

    2005-01-01

    at the atomic level about the structural and dynamical features of proteins-with the ability of molecular dynamics simulations to explore a wide range of protein conformations. We illustrate the method for human ubiquitin in solution and find that there is considerable conformational heterogeneity throughout......We present a protocol for the experimental determination of ensembles of protein conformations that represent simultaneously the native structure and its associated dynamics. The procedure combines the strengths of nuclear magnetic resonance spectroscopy-for obtaining experimental information...... the protein structure. The interior atoms of the protein are tightly packed in each individual conformation that contributes to the ensemble but their overall behaviour can be described as having a significant degree of liquid-like character. The protocol is completely general and should lead to significant...

  15. Evaluation of a novel noninvasive ICP monitoring device in patients undergoing invasive ICP monitoring: preliminary results.

    Science.gov (United States)

    Ganslandt, Oliver; Mourtzoukos, Stylianos; Stadlbauer, Andreas; Sommer, Björn; Rammensee, Rudolf

    2017-08-08

    OBJECTIVE There is no established method of noninvasive intracranial pressure (NI-ICP) monitoring that can serve as an alternative to the gold standards of invasive monitoring with external ventricular drainage or intraparenchymal monitoring. In this study a new method of NI-ICP monitoring performed using algorithms to determine ICP based on acoustic properties of the brain was applied in patients undergoing invasive ICP (I-ICP) monitoring, and the results were analyzed. METHODS In patients with traumatic brain injury and subarachnoid hemorrhage who were undergoing treatment in a neurocritical intensive care unit, the authors recorded ICP using the gold standard method of invasive external ventricular drainage or intraparenchymal monitoring. In addition, the authors simultaneously measured the ICP noninvasively with a device (the HS-1000) that uses advanced signal analysis algorithms for acoustic signals propagating through the cranium. To assess the accuracy of the NI-ICP method, data obtained using both I-ICP and NI-ICP monitoring methods were analyzed with MATLAB to determine the statistical significance of the differences between the ICP measurements obtained using NI-ICP and I-ICP monitoring. RESULTS Data were collected in 14 patients, yielding 2543 data points of continuous parallel ICP values in recordings obtained from I-ICP and NI-ICP. Each of the 2 methods yielded the same number of data points. For measurements at the ≥ 17-mm Hg cutoff, which was arbitrarily chosen for this preliminary analysis, the sensitivity and specificity for the NI-ICP monitoring were found to be 0.7541 and 0.8887, respectively. Linear regression analysis indicated that there was a strong positive relationship between the measurements. Differential pressure between NI-ICP and I-ICP was within ± 3 mm Hg in 63% of data-paired readings and within ± 5 mm Hg in 85% of data-paired readings. The receiver operating characteristic-area under the curve analysis revealed that the area

  16. Least Absolute Regression Network Analysis of the murine osteoblast differentiation network

    NARCIS (Netherlands)

    Someren, E.P. van; Vaes, B.L.T.; Steegenga, W.T.; Sijbers, A.M.; Dechering, K.J.; Reinders, M.J.

    2005-01-01

    MOTIVATION: We propose a reverse engineering scheme to discover genetic regulation from genome-wide transcription data that monitors the dynamic transcriptional response after a change in cellular environment. The interaction network is estimated by solving a linear model using simultaneous

  17. Simultaneous entanglement swapping of multiple orbital angular momentum states of light.

    Science.gov (United States)

    Zhang, Yingwen; Agnew, Megan; Roger, Thomas; Roux, Filippus S; Konrad, Thomas; Faccio, Daniele; Leach, Jonathan; Forbes, Andrew

    2017-09-21

    High-bit-rate long-distance quantum communication is a proposed technology for future communication networks and relies on high-dimensional quantum entanglement as a core resource. While it is known that spatial modes of light provide an avenue for high-dimensional entanglement, the ability to transport such quantum states robustly over long distances remains challenging. To overcome this, entanglement swapping may be used to generate remote quantum correlations between particles that have not interacted; this is the core ingredient of a quantum repeater, akin to repeaters in optical fibre networks. Here we demonstrate entanglement swapping of multiple orbital angular momentum states of light. Our approach does not distinguish between different anti-symmetric states, and thus entanglement swapping occurs for several thousand pairs of spatial light modes simultaneously. This work represents the first step towards a quantum network for high-dimensional entangled states and provides a test bed for fundamental tests of quantum science.Entanglement swapping in high dimensions requires large numbers of entangled photons and consequently suffers from low photon flux. Here the authors demonstrate entanglement swapping of multiple spatial modes of light simultaneously, without the need for increasing the photon numbers with dimension.

  18. remote sensor network

    Science.gov (United States)

    von Unold, Georg; Junker, Astrid; Altmann, Thomas

    2016-04-01

    High-throughput (HT) plant phenotyping systems enable the quantitative analysis of a variety of plant features in a fully automated fashion. The comprehensive phenomics infrastructure at IPK comprises three LemnaTec conveyor belt-based (plant-to-sensor) systems for the simultaneous analysis of large numbers of individual plants of different sizes. For monitoring of environmental conditions within the plant growth area and soil conditions in individual pots, highly modular and flexible remote sensing devices are required. We present the architecture of a wireless sensor network implemented in the HT plant phenotyping systems at IPK in the frame of the German Plant Phenotyping Network (DPPN). This system comprises 350 soil monitoring modules, each measuring water content, water matrix potential, temperature and electric conductivity. Furthermore small and large sensor platforms enable the continuous monitoring of environmental parameters such as incident photosynthetic active radiation, total radiation balance, relative humidity and CO2 concentration and more. Finally we present an introduction into data management and maintenance."

  19. Simultaneously measuring multiple protein interactions and their correlations in a cell by Protein-interactome Footprinting.

    Science.gov (United States)

    Luo, Si-Wei; Liang, Zhi; Wu, Jia-Rui

    2017-03-24

    Quantitatively detecting correlations of multiple protein-protein interactions (PPIs) in vivo is a big challenge. Here we introduce a novel method, termed Protein-interactome Footprinting (PiF), to simultaneously measure multiple PPIs in one cell. The principle of PiF is that each target physical PPI in the interactome is simultaneously transcoded into a specific DNA sequence based on dimerization of the target proteins fused with DNA-binding domains. The interaction intensity of each target protein is quantified as the copy number of the specific DNA sequences bound by each fusion protein dimers. Using PiF, we quantitatively reveal dynamic patterns of PPIs and their correlation network in E. coli two-component systems.

  20. Demonstration of microcantilever array with simultaneous readout using an in-plane photonic transduction method.

    Science.gov (United States)

    Hu, Weisheng; Anderson, Ryan; Qian, Yusheng; Song, Jigou; Noh, Jong Wook; Kim, Seunghyun; Nordin, Gregory P

    2009-08-01

    We demonstrate a microcantilever array with an in-plane photonic transduction method for simultaneous readout of each microcantilever. The array is fabricated on a silicon-on-insulator substrate. Rib waveguides in conjunction with a compact waveguide splitter network comprised of trench-based splitters and trench-based bends route light from a single optical input to each microcantilever on the chip. Light propagates down a rib waveguide integrated into the microcantilever and, at the free end of the microcantilever, crosses a small gap. Light is captured in static asymmetric multimode waveguides that terminate in Y-branches, the outputs of which are imaged onto an InGaAs line scan camera. A differential signal for each microcantilever is simultaneously formed from the two outputs of the corresponding Y-branch. We demonstrate that reasonable signal uniformity is obtained with a scaled differential signal for seven out of nine surviving microcantilevers in an array.

  1. DEMONSTRATION OF AN ADVANCED INTEGRATED CONTROL SYSTEM FOR SIMULTANEOUS EMISSIONS REDUCTION

    Energy Technology Data Exchange (ETDEWEB)

    Suzanne Shea; Randhir Sehgal; Ilga Celmins; Andrew Maxson

    2002-02-01

    The primary objective of the project titled ''Demonstration of an Advanced Integrated Control System for Simultaneous Emissions Reduction'' was to demonstrate at proof-of-concept scale the use of an online software package, the ''Plant Environmental and Cost Optimization System'' (PECOS), to optimize the operation of coal-fired power plants by economically controlling all emissions simultaneously. It combines physical models, neural networks, and fuzzy logic control to provide both optimal least-cost boiler setpoints to the boiler operators in the control room, as well as optimal coal blending recommendations designed to reduce fuel costs and fuel-related derates. The goal of the project was to demonstrate that use of PECOS would enable coal-fired power plants to make more economic use of U.S. coals while reducing emissions.

  2. Simultaneous fMRI-PET of the opioidergic pain system in human brain

    DEFF Research Database (Denmark)

    Wey, Hsiao-Ying; Catana, Ciprian; Hooker, Jacob M

    2014-01-01

    MRI and PET provide complementary information for studying brain function. While the potential use of simultaneous MRI/PET for clinical diagnostic and disease staging has been demonstrated recently; the biological relevance of concurrent functional MRI-PET brain imaging to dissect neurochemically...... and striatum related to pain processing, while modality specific brain networks were also found. Co-localized fMRI and PET signal changes in the thalamus were positively correlated suggesting that pain-induced changes in opioid neurotransmission contribute a significant component of the fMRI signal change...... in this region. Simultaneous fMRI-PET provides unique opportunities allowing us to relate specific neurochemical events to functional hemodynamic activation and to investigate the impacts of neurotransmission on neurovascular coupling of the human brain in vivo....

  3. Patient selection optimization following combined abdominal procedures: analysis of 4925 patients undergoing panniculectomy/abdominoplasty with or without concurrent hernia repair.

    Science.gov (United States)

    Koolen, Pieter G L; Ibrahim, Ahmed M S; Kim, Kuylhee; Sinno, Hani H; Lee, Bernard T; Schneider, Benjamin E; Jones, Daniel B; Lin, Samuel J

    2014-10-01

    Massive weight loss following bariatric surgery causes unwanted excess skin and subcutaneous tissue. Intraoperative abdominal wall exposure during abdominal contouring surgery provides the possibility for concurrent ventral, umbilical, or inguinal hernia repair. The authors evaluated the incidence of postoperative complications following abdominal contouring surgery with or without concurrent hernia repair and the impact of surgical specialty. Analysis of patients undergoing abdominal contouring surgery with or without concurrent hernia repair was performed using the American College of Surgeons National Surgical Quality Improvement Program from 2005 to 2011. The incidence of postoperative complications was determined. Logistic regression assessed influence of demographics and comorbidities on postoperative outcomes. Control group (body mass index > 27.5) and high-risk group (body mass index > 40) undergoing a hernia repair were also included for comparison. Among 4925 patients, 63.7 percent underwent abdominoplasty and/or panniculectomy only; 36.3 percent underwent a simultaneous hernia repair. The abdominal contouring surgery with simultaneous hernia repair group had a higher complication rate than the abdominal contouring surgery group (18.3 percent versus 9.8 percent, p hernia repair group. Patients undergoing hernia repair with abdominal contouring surgery may have higher postoperative complication rates than after abdominal contouring surgery alone. Hypertension, smoking, and chronic steroid use were predictors for negative outcomes. Furthermore, surgical specialty is associated with significantly different complication rates. Therapeutic, III.

  4. Impairments in "top-down" processing in bipolar disorder: a simultaneous fMRI-GSR study.

    Science.gov (United States)

    Lagopoulos, Jim; Malhi, Gin

    2011-05-31

    Understanding the underlying neurobiology of bipolar disorder especially in the euthymic state is essential to furthering our understanding of pertinent psychiatric questions involving the observed symptomatology of the illness. In this study we investigated the mechanisms that underpin the modulation of affect in bipolar disorder to examine the contributions of cortico-limbic brain networks in the processing of affect. We employed a simultaneous functional magnetic resonance imaging and galvanic skin response methodology to investigate top-down networks in euthymic bipolar patients and healthy controls. Galvanic skin responsivity was used to partition neural epochs in which arousal pertaining to the appreciation of disgust stimuli was processed. The results of this study demonstrate that patients with bipolar disorder exhibited impairments in the recruitment of top-down brain networks and as such were unable to engage, to the same extent as matched controls, essential prefrontal processing needed to evaluate emotional salience. Partitioning top-down networks on the basis of arousal measures provided a context within which the modulation of brain networks specialised for the processing of emotion, as well as their interplay with other brain regions including the frontal lobes, could be studied. 2010 Elsevier Ireland Ltd. All rights reserved.

  5. Multiplex congruence network of natural numbers

    Science.gov (United States)

    Yan, Xiao-Yong; Wang, Wen-Xu; Chen, Guan-Rong; Shi, Ding-Hua

    2016-03-01

    Congruence theory has many applications in physical, social, biological and technological systems. Congruence arithmetic has been a fundamental tool for data security and computer algebra. However, much less attention was devoted to the topological features of congruence relations among natural numbers. Here, we explore the congruence relations in the setting of a multiplex network and unveil some unique and outstanding properties of the multiplex congruence network. Analytical results show that every layer therein is a sparse and heterogeneous subnetwork with a scale-free topology. Counterintuitively, every layer has an extremely strong controllability in spite of its scale-free structure that is usually difficult to control. Another amazing feature is that the controllability is robust against targeted attacks to critical nodes but vulnerable to random failures, which also differs from ordinary scale-free networks. The multi-chain structure with a small number of chain roots arising from each layer accounts for the strong controllability and the abnormal feature. The multiplex congruence network offers a graphical solution to the simultaneous congruences problem, which may have implication in cryptography based on simultaneous congruences. Our work also gains insight into the design of networks integrating advantages of both heterogeneous and homogeneous networks without inheriting their limitations.

  6. Postural balance in Alzheimer's disease patients undergoing sensory pitfalls

    Directory of Open Access Journals (Sweden)

    Brunna Berton

    Full Text Available Abstract Despite consensus regarding the interference of cognitive processes on the human balance, the impact that different sensory stimuli have on the stabilometric measures remains unclear. Here, we investigated changes in the postural balance of individuals with Alzheimer's disease (AD and in healthy controls undergoing different proprioceptive and somesthetic pitfalls. We included 17 subjects submitted to eight sensorimotor dynamics with differences in the support bases, contact surfaces, and visual clues. The measurements used to assess participants balance were as follows: position of the body in space, range of instability, area of the support base, and velocity of postural control. From a total of 56 cross-sectional analyses, 21.42% pointed out differences between groups. Longitudinal analyses showed that tasks with proprioceptive and somesthetic pitfalls similarly impact imbalance in both groups. The current results suggest that AD subjects and healthy controls had different patterns submitted to balance, but suffered similar interference when undergoing proprioceptive and somesthetic challenges.

  7. Efficacy of ceftibuten for pediatric patients undergoing adenotonsillectomy.

    Science.gov (United States)

    Juarbe, C

    2000-01-01

    A survey between Otolaryngologist Head and Neck Surgeons in Puerto Rico and a prospective study was done, to evaluate the efficacy of ceftibuten in pediatric patients undergoing adenotonsillectomy. Surgery of the tonsils and adenoids is the most common operation performed in the pediatric age by the Otolaryngologist Head and Neck Surgeons in Puerto Rico. Over 70% are performed in a ambulatory setting and almost all of the patients are given antibiotics after surgery. Ceftibuten was given to 112 pediatrics patients after surgery. Adenotonsillectomy is a painful operation and children do not take medication well after surgery. One of the benefits of this third generation cephalosporin, is that is given once a day. Twenty events were reported taking the medication, but only seven patients had to discontinue its use. Ceftibuten had a tolerance rate of 94%. Ceftibuten seems to be a safe antibiotic to use in pediatric patients undergoing adenotonsillectomy and has the convenience of being given once a day.

  8. Simultaneous Transmit and Receive (STAR) Mobile Testbed

    Science.gov (United States)

    2015-07-24

    allowed for the interactions and scattering effects of the vehicle’s large metal surface on the antenna radiation patterns to be investigated. Cables...Cancellation 15.1 11.5 dB Spatial Cancellation at t0 32.4 33.1 dB Total Isolation at t0 101.6 97.9 dB isotropic radiated power (EIRP), along with the...K. Ramakrishnan, C. Rice, and N. Shankaranarayanan, “Design and characterization of a full-duplex multiantenna system for wifi networks,” Vehicular

  9. Quality of life of women undergoing treatment for cervical cancer

    OpenAIRE

    Francieli Ana Dallabrida; Marli Maria Loro; Cleci de Lourdes Schmidt Piovesan Rosanelli; Marina Mazzuco de Souza; Joseila Sonego Gomes; Adriane Cristina Bernat Kolankiewicz

    2014-01-01

    This study aimed to evaluate the quality of life of women with cervical cancer. This is a cross-sectional, descriptive study developed with 43 women undergoing oncological treatment assisted at an Oncology High Complexity Center, in the Southern region of Brazil. The instrument used was the European Organization for Research and Treatment of Cancer – Quality of Life Questionnaire Core-30, and the data were analyzed through descriptive statistics. The average age was 54.6 years old. Married wo...

  10. Adequacy of hemodialysis in Nepalese patients undergoing maintenance hemodialysis

    OpenAIRE

    P Sultania; Sanjib Kumar Sharma; Sharma SK

    2009-01-01

    INTRODUCTION: Inadequate dialysis accounts for the high mortality in patients with end stage renal disease (ESRD). In Nepal, due to various factors including financial and logistic limitations, hemodialysis is mostly performed twice-a-week. This study was undertaken to look at adequacy of dialysis in patients undergoing maintenance hemodialysis in Nepal where the patients profile, in terms of diet, body muscle mass, nutritional status etc are different from western world. METHODS: In...

  11. Creating and Validating Educational Material for Patients Undergoing Orthognathic Surgery

    OpenAIRE

    Sousa, Cristina Silva; Turrini, Ruth Natalia Teresa

    2012-01-01

    Purpose: To create and validate educational material for patients undergoing orthognathic surgery. Methods: The design included five phases: (a) a review of the literature regarding surgical complications; (b) gathering information on the needs of patients through blogs and virtual communities; (c) evaluating patient perceptions of the post-operative period through a focus group; (d) obtaining information through specialists using the Delphi technique and validation by judges; and (e) vali...

  12. Radiation dose estimation of patients undergoing lumbar spine radiography

    OpenAIRE

    Prince Kwabena Gyekye; Adu Simon; Emi-Reynolds Geoffrey; Yeboah Johnson; Inkoom Stephen; Cynthia Kaikor Engmann; Wotorchi-Gordon Samuel

    2013-01-01

    Radiation dose to organs of 100 adult patients undergoing lumbar spine (LS) radiography at a University Hospital have been assessed. Free in air kerma measurement using an ionization chamber was used for the patient dosimetry. Organ and effective dose to the patients were estimated using PCXMC (version 1.5) software. The organs that recorded significant dose due to LS radiography were lungs, stomach, liver, adrenals, kidney, pancreas, spleen, galbladder, and the heart. It was observed that th...

  13. Periodontal Management of a Patient Undergoing Liver Transplantation.

    Science.gov (United States)

    Clozza, Emanuele; Segelnick, Stuart L; Sigal, Samuel H; Rovner, Deborah N; Weinberg, Mea A

    2016-01-01

    This case report describes the periodontal management of a patient with end-stage liver disease undergoing liver transplantation. In the first part of this article, all medical and dental findings are reported to elaborate adequate diagnoses. A patient-specific treatment plan was structured given the challenging periodontal and systemic scenarios. The second part describes the periodontal therapy delivered in close interaction with the referring physicians. Last, the article reviews current principles and protocols in managing these patients.

  14. Factors associated with treatment adherence of Brazilian patients undergoing hemodialysis

    OpenAIRE

    Nakao, Renata Tamie; Gorayeb, Ricardo; da Costa, José Abrão Cardeal

    2016-01-01

    Objective: To evaluate patients’ adherence to hemodialysis (HD) and its relationship to psychosocial variables. Methods: Participated in the study 64 adult patients undergoing HD, assessed in regard to depression, anxiety, social support, disease and treatment knowledge, and adherence. Results: It was found association between sex and adherence to HD, to diet and to medication, as well as between schooling and overall adherence. There is association between disease knowledge and depression, w...

  15. Network interruptions

    CERN Document Server

    2005-01-01

    On Sunday 12 June 2005, a site-wide security software upgrade will be performed on all CERN network equipment. This maintenance operation will cause at least 2 short network interruptions of 2 minutes on each equipment item. There are hundreds of such items across the CERN site (Meyrin, Prévessin and all SPS and LHC pits), and it will thus take the whole day to treat them all. All network users and services will be affected. Central batch computing services will be interrupted during this period, expected to last from 8 a.m. until late evening. Job submission will still be possible but no jobs will actually be run. It is hoped to complete the computer centre upgrades in the morning so that stable access can be restored to lxplus, afs and nice services as soon as possible; this cannot be guaranteed, however. The opportunity will be used to interrupt and perform upgrades on the CERN Document Servers.

  16. Network Survivability

    DEFF Research Database (Denmark)

    Marzo, José L.; Stidsen, Thomas Riis; Ruepp, Sarah Renée

    2010-01-01

    – are vital to modern services such as mobile telephony, online banking and VoIP. This book examines communication networking from a mathematical viewpoint. The contributing authors took part in the European COST action 293 – a four-year program of multidisciplinary research on this subject. In this book...... they offer introductory overviews and state-of-the-art assessments of current and future research in the fields of broadband, optical, wireless and ad hoc networks. Particular topics of interest are design, optimization, robustness and energy consumption. The book will be of interest to graduate students......, researchers and practitioners in the areas of networking, theoretical computer science, operations research, distributed computing and mathematics....

  17. Nuclear networking.

    Science.gov (United States)

    Xie, Wei; Burke, Brian

    2017-07-04

    Nuclear lamins are intermediate filament proteins that represent important structural components of metazoan nuclear envelopes (NEs). By combining proteomics and superresolution microscopy, we recently reported that both A- and B-type nuclear lamins form spatially distinct filament networks at the nuclear periphery of mouse fibroblasts. In particular, A-type lamins exhibit differential association with nuclear pore complexes (NPCs). Our studies reveal that the nuclear lamina network in mammalian somatic cells is less ordered and more complex than that of amphibian oocytes, the only other system in which the lamina has been visualized at high resolution. In addition, the NPC component Tpr likely links NPCs to the A-type lamin network, an association that appears to be regulated by C-terminal modification of various A-type lamin isoforms. Many questions remain, however, concerning the structure and assembly of lamin filaments, as well as with their mode of association with other nuclear components such as peripheral chromatin.

  18. Juggling Act: Re-Planning and Building on Observatory...Simultaneously!

    Science.gov (United States)

    Zavala, Eddie; Daws, Patricia

    2011-01-01

    SOFIA (Stratospheric Observatory for Infrared Astronomy) is a major SMD program that has been required to meet several requirements and implement major planning and business initiatives overthe past 1 1/2 years, in the midst of system development and flight test phases. The program was required to implementing JCL and EVM simultaneously, as well as undergo a major replan and Standing Review Board - and all without impacting technical schedule progress. The team developed innovative processes that met all the requirements, and improved Program Management process toolsets. The SOFIA team, being subject to all the typical budget constraints, found ways to leverage existing roles in new ways to meet the requirements without creating unmanageable overhead. The team developed strategies and value added processes - such as improved risk identification, structured reserves management, cost/risk integration - so that the effort expended resulted in a positive return to the program.

  19. Preoperative medical testing in Medicare patients undergoing cataract surgery.

    Science.gov (United States)

    Chen, Catherine L; Lin, Grace A; Bardach, Naomi S; Clay, Theodore H; Boscardin, W John; Gelb, Adrian W; Maze, Mervyn; Gropper, Michael A; Dudley, R Adams

    2015-04-16

    Routine preoperative testing is not recommended for patients undergoing cataract surgery, because testing neither decreases adverse events nor improves outcomes. We sought to assess adherence to this guideline, estimate expenditures from potentially unnecessary testing, and identify patient and health care system characteristics associated with potentially unnecessary testing. Using an observational cohort of Medicare beneficiaries undergoing cataract surgery in 2011, we determined the prevalence and cost of preoperative testing in the month before surgery. We compared the prevalence of preoperative testing and office visits with the mean percentage of beneficiaries who underwent tests and had office visits during the preceding 11 months. Using multivariate hierarchical analyses, we examined the relationship between preoperative testing and characteristics of patients, health system characteristics, surgical setting, care team, and occurrence of a preoperative office visit. Of 440,857 patients, 53% had at least one preoperative test in the month before surgery. Expenditures on testing during that month were $4.8 million higher and expenditures on office visits $12.4 million higher (42% and 78% higher, respectively) than the mean monthly expenditures during the preceding 11 months. Testing varied widely among ophthalmologists; 36% of ophthalmologists ordered preoperative tests for more than 75% of their patients. A patient's probability of undergoing testing was associated mainly with the ophthalmologist who managed the preoperative evaluation. Preoperative testing before cataract surgery occurred frequently and was more strongly associated with provider practice patterns than with patient characteristics. (Funded by the Foundation for Anesthesia Education and Research and the Grove Foundation.).

  20. Sinusitis in patients undergoing allogeneic bone marrow transplantation - a review.

    Science.gov (United States)

    Drozd-Sokolowska, Joanna Ewa; Sokolowski, Jacek; Wiktor-Jedrzejczak, Wieslaw; Niemczyk, Kazimierz

    Sinusitis is a common morbidity in general population, however little is known about its occurrence in severely immunocompromised patients undergoing allogeneic hematopoietic stem cell transplantation. The aim of the study was to analyze the literature concerning sinusitis in patients undergoing allogeneic bone marrow transplantation. An electronic database search was performed with the objective of identifying all original trials examining sinusitis in allogeneic hematopoietic stem cell transplant recipients. The search was limited to English-language publications. Twenty five studies, published between 1985 and 2015 were identified, none of them being a randomized clinical trial. They reported on 31-955 patients, discussing different issues i.e. value of pretransplant sinonasal evaluation and its impact on post-transplant morbidity and mortality, treatment, risk factors analysis. Results from analyzed studies yielded inconsistent results. Nevertheless, some recommendations for good practice could be made. First, it seems advisable to screen all patients undergoing allogeneic hematopoietic stem cell transplantation with Computed Tomography (CT) prior to procedure. Second, patients with symptoms of sinusitis should be treated before hematopoietic stem cell transplantation (HSCT), preferably with conservative medical approach. Third, patients who have undergone hematopoietic stem cell transplantation should be monitored closely for sinusitis, especially in the early period after transplantation. Copyright © 2016 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved.

  1. Psychosocial factors predicting the motivation to undergo cosmetic surgery.

    Science.gov (United States)

    von Soest, Tilmann; Kvalem, Ingela L; Skolleborg, Knut Chr; Roald, Helge E

    2006-01-01

    The present study investigates psychological factors expected to predict the motivation to undergo cosmetic surgery. It is hypothesized that body image, self-esteem, teasing history, acceptance of cosmetic surgery in the individual's environment, and self-monitoring relate to motivation to have cosmetic surgery. Questionnaire data were obtained from 907 participants who responded to a survey distributed to a representative sample of Norwegian women aged 22 to 55 years. A second sample of 195 female prospective cosmetic surgery patients was recruited from a plastic surgery clinic. Measures of the hypothesized predictor variables were obtained from both samples. Surgery motivation was operationalized in two different ways. First, the women in the first sample were asked to indicate whether they wished to undergo cosmetic surgery, such that women who wished to have surgery could be compared with those who did not. Second, prospective patients were compared with women from the first sample who indicated that they did not wish to have cosmetic surgery. Analyses revealed all predictor variables but self-esteem to be related to either the wish or the decision to undergo surgery, or to both. Social acceptance of cosmetic surgery and body image were the strongest predictors of cosmetic surgery motivation. The study gives new insights into psychological factors predicting cosmetic surgery motivation. Furthermore, the influence of social factors on cosmetic surgery motivation is emphasized, and it is suggested that these factors be included in future research designs.

  2. Predicting blood transfusion in patients undergoing minimally invasive oesophagectomy.

    Science.gov (United States)

    Schneider, Crispin; Boddy, Alex P; Fukuta, Junaid; Groom, William D; Streets, Christopher G

    2014-12-01

    To evaluate predictors of allogenic blood transfusion requirements in patients undergoing minimal invasive oesophagectomy at a tertiary high volume centre for oesophago-gastric surgery. Retrospective analysis of all patients undergoing minimal access oesophagectomy in our department between January 2010 and December 2011. Patients were divided into two groups depending on whether they required a blood transfusion at any time during their index admission. Factors that have been shown to influence perioperative blood transfusion requirements in major surgery were included in the analysis. Binary logistic regression analysis was performed to determine the impact of patient and perioperative characteristics on transfusion requirements during the index admission. A total of 80 patients underwent minimal access oesophagectomy, of which 61 patients had a laparoscopic assisted oesophagectomy and 19 patients had a minimal invasive oesophagectomy. Perioperative blood transfusion was required in 28 patients at any time during hospital admission. On binary logistic regression analysis, a lower preoperative haemoglobin concentration (p blood transfusion requirements. It has been reported that requirement for blood transfusion can affect long-term outcomes in oesophageal cancer resection. Two factors which could be addressed preoperatively; haemoglobin concentration and type of oesophageal resection, may be valuable in predicting blood transfusions in patients undergoing minimally invasive oesophagectomy. Our analysis revealed that preoperative haemoglobin concentration, occurrence of significant complications and type of minimal access oesophagectomy predicted blood transfusion requirements in the patient population examined. Copyright © 2014 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

  3. Industrial Networks

    DEFF Research Database (Denmark)

    Karlsson, Christer

    2015-01-01

    the focus of operations management from managing the own organization to continuously developing and managing a network of external and internal resources forming a production system. This perspective may be called managing an “extraprise” rather than an “enterprise.” It should be noted that “an industrial...... network” should not be seen as an organizational form but as a perspective that can be used to enrich one's understanding of organizations. The industrial network perspective has three basic building blocks: actors, resources, and activities. The three building blocks and their relations constitute...

  4. Impact of multimodal preoperative preparation program on children undergoing surgery

    Directory of Open Access Journals (Sweden)

    Priya Reshma Aranha

    2017-01-01

    Full Text Available Background: The advanced era of technological development in child health care has resulted in more pediatric procedures being performed in various settings. Millions of children undergo surgery every year which is a stressful event. Many nonpharmacological strategies are being used to manage the preoperative fear and anxiety in children. The current study aims to assess the effectiveness of multimodal preoperative preparation program (MPPP on children undergoing surgery in terms of its effect on the psychophysiological parameters. Objective: The aim of this study is to assess the effectiveness of MPPP on the psychophysiological parameters of children undergoing surgery. Materials and Methods: A quasi-experimental study was conducted in a selected multi-specialty hospital. Using the purposive sampling technique, a total of 110 children aged 8–12 years were assigned to nonintervention (n = 55 and intervention (n = 55 groups, respectively. The MPPP was administered to the intervention group. The children in the nonintervention group received the routine preoperative care. Child's fear and anxiety was assessed on admission, prior to shifting the child to operation theater (OT, 24 and 48 h after surgery, whereas child's pulse, respiration, blood pressure (BP, and oxygen saturation was assessed on admission, prior to shifting the child to OT, 6, 12, 24, and 48 h after surgery and pain was assessed at 24 and 48 h after surgery. Results: The mean fear and anxiety scores of children were significantly lower in the intervention group than that of nonintervention group (P 0.05. This study also found that there is a significant association between the psychophysiological parameters of children with the selected demographic variables (P < 0.05. A positive correlation was found between the psychological and physiological parameters of children undergoing surgery. Conclusion: The MPPP is effective on psychophysiological parameters of children undergoing

  5. Network science landers for Mars

    DEFF Research Database (Denmark)

    Harri, A.M.; Marsal, O.; Lognonne, P.

    1999-01-01

    The NetLander Mission will deploy four landers to the Martian surface. Each lander includes a network science payload with instrumentation for studying the interior of Mars, the atmosphere and the subsurface, as well as the ionospheric structure and geodesy. The NetLander Mission is the first...... FMI (the Finnish Meteorological Institute), DLR (the German Space Agency), and other research institutes. According to current plans, the NetLander Mission will be launched in 2005 by means of an Ariane V launch, together with the Mars Sample Return mission. The landers will be separated from...... the spacecraft and targeted to their locations on the Martian surface several days prior to the spacecraft's arrival at Mars. The landing system employs parachutes and airbags. During the baseline mission of one Martian year, the network payloads will conduct simultaneous seismological, atmospheric, magnetic...

  6. Multitask Diffusion Adaptation Over Networks

    Science.gov (United States)

    Chen, Jie; Richard, Cedric; Sayed, Ali H.

    2014-08-01

    Adaptive networks are suitable for decentralized inference tasks, e.g., to monitor complex natural phenomena. Recent research works have intensively studied distributed optimization problems in the case where the nodes have to estimate a single optimum parameter vector collaboratively. However, there are many important applications that are multitask-oriented in the sense that there are multiple optimum parameter vectors to be inferred simultaneously, in a collaborative manner, over the area covered by the network. In this paper, we employ diffusion strategies to develop distributed algorithms that address multitask problems by minimizing an appropriate mean-square error criterion with $\\ell_2$-regularization. The stability and convergence of the algorithm in the mean and in the mean-square sense is analyzed. Simulations are conducted to verify the theoretical findings, and to illustrate how the distributed strategy can be used in several useful applications related to spectral sensing, target localization, and hyperspectral data unmixing.

  7. Simultaneous, selective soldering of solar cells via induction heating; Simultanes, punktuelles Verloeten von Solarzellen mittels Induktionserwaermung

    Energy Technology Data Exchange (ETDEWEB)

    Schmitt, Peter [Fraunhofer-Institut fuer Solare Energiesysteme ISE, Freiburg (Germany)

    2010-12-15

    This paper is dealing with the use of induction heating for the soldering of crystalline silicon (c-Si) solar cells. An inductor which is able to solder a sensitive solar cell in a selective and simultaneous way can reach joints of good quality in a fast and contactless process. Due to this it is possible to reduce the cost of interconnection and increase the efficiency of the module. (orig.)

  8. A Spectrum Handoff Scheme for Optimal Network Selection in NEMO Based Cognitive Radio Vehicular Networks

    Directory of Open Access Journals (Sweden)

    Krishan Kumar

    2017-01-01

    Full Text Available When a mobile network changes its point of attachments in Cognitive Radio (CR vehicular networks, the Mobile Router (MR requires spectrum handoff. Network Mobility (NEMO in CR vehicular networks is concerned with the management of this movement. In future NEMO based CR vehicular networks deployment, multiple radio access networks may coexist in the overlapping areas having different characteristics in terms of multiple attributes. The CR vehicular node may have the capability to make call for two or more types of nonsafety services such as voice, video, and best effort simultaneously. Hence, it becomes difficult for MR to select optimal network for the spectrum handoff. This can be done by performing spectrum handoff using Multiple Attributes Decision Making (MADM methods which is the objective of the paper. The MADM methods such as grey relational analysis and cost based methods are used. The application of MADM methods provides wider and optimum choice among the available networks with quality of service. Numerical results reveal that the proposed scheme is effective for spectrum handoff decision for optimal network selection with reduced complexity in NEMO based CR vehicular networks.

  9. Nepal Networking

    DEFF Research Database (Denmark)

    Hansen, Annette Skovsted

    that their personal networks engage not only their families, but also their home communities and by extension Nepal. The two women constitute weak links between their country and other countries and as such they function as bridges or channels for transmission of practices, ideas, knowledge, and artefacts. However...

  10. Network Society

    DEFF Research Database (Denmark)

    Clausen, Lars; Tække, Jesper

    2018-01-01

    the five strands of theory on the network society. Each theoretical position has its specific implications for acting toward strategic goals. In its entirety, the five perspectives give a thorough understanding of the conditions for successful strategic communication in the 21st century....

  11. Network Coding

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 15; Issue 7. Network Coding. K V Rashmi Nihar B Shah P Vijay Kumar. General Article Volume 15 Issue 7 July 2010 pp 604-621. Fulltext. Click here to view fulltext PDF. Permanent link: http://www.ias.ac.in/article/fulltext/reso/015/07/0604-0621. Keywords.

  12. Network Society

    DEFF Research Database (Denmark)

    Clausen, Lars; Tække, Jesper

    2017-01-01

    the five strands of theory on the network society. Each theoretical position has its specific implications for acting toward strategic goals. In its entirety, the five perspectives give a thorough understanding of the conditions for successful strategic communication in the 21st century....

  13. distribution network

    African Journals Online (AJOL)

    user

    This paper examined the acidic properties of distribution transformer oil insulation in service at Jericho distribution network Ibadan, Nigeria. Five oil samples each from six distribution transformers (DT1, DT2, DT3, DT4 and DT5) making a total of thirty samples were taken from different installed distribution transformers all ...

  14. Classification-based Multi-client Video Transmission over Heterogeneous Networks

    OpenAIRE

    Bo Li; Peng Wang; Yongfei Zhang

    2013-01-01

    These Real-time video streaming over networks operates under stringent network resource constraints, with multiple video clients competing for limited network resources. In this paper, we study the problem of bandwidth allocation for video transmission over heterogeneous networks, with multiple video clients connecting to the video server simultaneously and demanding for the video services, and aim to provide the best possible Quality of Service (QoS) under limited bandwidth of both the video...

  15. Genioglossus muscle advancement and simultaneous sliding genioplasty in the management of sleep apnoea.

    Science.gov (United States)

    Rojas, R; Chateau, R; Gaete, C; Muñoz, C

    2017-11-02

    Genioglossus muscle advancement (GMA) was reported in 1993 as an option for the surgical treatment of obstructive sleep apnoea syndrome (OSAS), in the context of phase I of the Stanford University (Powell-Riley) protocol. The rationale for this technique is the placement of tension on the base of the tongue, thus preventing the tongue from falling back into the posterior airway space. However, in retrognathic patients undergoing phase I of the Stanford University protocol, an additional genioplasty will provide a better aesthetic outcome. Furthermore, genioplasty is one of the most common and versatile techniques used for the correction of dentofacial deformities. The aim of this article is to describe a technique that allows a combination of genioglossus muscle advancement (GMA) and a simultaneous sliding genioplasty. This technique can be used in patients undergoing phase I surgery, or in patients in whom a sliding genioplasty could be complemented by GMA. The advantage of this procedure is the aesthetic enhancement obtained in GMA patients. The indications, contraindications, complications, and outcomes of surgery in the first 15 patients treated with this technique are reported herein. Copyright © 2017. Published by Elsevier Ltd.

  16. Simultaneous Mass Determination for Gravitationally Coupled Asteroids

    Energy Technology Data Exchange (ETDEWEB)

    Baer, James [Private address, 3210 Apache Road, Pittsburgh, PA 15241 (United States); Chesley, Steven R., E-mail: jimbaer1@earthlink.net [Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, Pasadena, CA 91109 (United States)

    2017-08-01

    The conventional least-squares asteroid mass determination algorithm allows us to solve for the mass of a large subject asteroid that is perturbing the trajectory of a smaller test asteroid. However, this algorithm is necessarily a first approximation, ignoring the possibility that the subject asteroid may itself be perturbed by the test asteroid, or that the encounter’s precise geometry may be entangled with encounters involving other asteroids. After reviewing the conventional algorithm, we use it to calculate the masses of 30 main-belt asteroids. Compared to our previous results, we find new mass estimates for eight asteroids (11 Parthenope, 27 Euterpe, 51 Neimausa, 76 Freia, 121 Hermione, 324 Bamberga, 476 Hedwig, and 532 Herculina) and significantly more precise estimates for six others (2 Pallas, 3 Juno, 4 Vesta, 9 Metis, 16 Psyche, and 88 Thisbe). However, we also find that the conventional algorithm yields questionable results in several gravitationally coupled cases. To address such cases, we describe a new algorithm that allows the epoch state vectors of the subject asteroids to be included as solve-for parameters, allowing for the simultaneous solution of the masses and epoch state vectors of multiple subject and test asteroids. We then apply this algorithm to the same 30 main-belt asteroids and conclude that mass determinations resulting from current and future high-precision astrometric sources (such as Gaia ) should conduct a thorough search for possible gravitational couplings and account for their effects.

  17. Simultaneous Nanoscale Surface Charge and Topographical Mapping.

    Science.gov (United States)

    Perry, David; Al Botros, Rehab; Momotenko, Dmitry; Kinnear, Sophie L; Unwin, Patrick R

    2015-07-28

    Nanopipettes are playing an increasingly prominent role in nanoscience, for sizing, sequencing, delivery, detection, and mapping interfacial properties. Herein, the question of how to best resolve topography and surface charge effects when using a nanopipette as a probe for mapping in scanning ion conductance microscopy (SICM) is addressed. It is shown that, when a bias modulated (BM) SICM scheme is used, it is possible to map the topography faithfully, while also allowing surface charge to be estimated. This is achieved by applying zero net bias between the electrode in the SICM tip and the one in bulk solution for topographical mapping, with just a small harmonic perturbation of the potential to create an AC current for tip positioning. Then, a net bias is applied, whereupon the ion conductance current becomes sensitive to surface charge. Practically this is optimally implemented in a hopping-cyclic voltammetry mode where the probe is approached at zero net bias at a series of pixels across the surface to reach a defined separation, and then a triangular potential waveform is applied and the current response is recorded. Underpinned with theoretical analysis, including finite element modeling of the DC and AC components of the ionic current flowing through the nanopipette tip, the powerful capabilities of this approach are demonstrated with the probing of interfacial acid-base equilibria and high resolution imaging of surface charge heterogeneities, simultaneously with topography, on modified substrates.

  18. Simultaneous brightness contrast of foraging Papilio butterflies

    Science.gov (United States)

    Kinoshita, Michiyo; Takahashi, Yuki; Arikawa, Kentaro

    2012-01-01

    This study focuses on the sense of brightness in the foraging Japanese yellow swallowtail butterfly, Papilio xuthus. We presented two red discs of different intensity on a grey background to butterflies, and trained them to select one of the discs. They were successfully trained to select either a high intensity or a low intensity disc. The trained butterflies were tested on their ability to perceive brightness in two different protocols: (i) two orange discs of different intensity presented on the same intensity grey background and (ii) two orange discs of the same intensity separately presented on a grey background that was either higher or lower in intensity than the training background. The butterflies trained to high intensity red selected the orange disc of high intensity in protocol 1, and the disc on the background of low intensity grey in protocol 2. We obtained similar results in another set of experiments with purple discs instead of orange discs. The choices of the butterflies trained to low intensity red were opposite to those just described. Taken together, we conclude that Papilio has the ability to learn brightness and darkness of targets independent of colour, and that they have the so-called simultaneous brightness contrast. PMID:22179808

  19. Simultaneous quaternion estimation (QUEST) and bias determination

    Science.gov (United States)

    Markley, F. Landis

    1989-01-01

    Tests of a new method for the simultaneous estimation of spacecraft attitude and sensor biases, based on a quaternion estimation algorithm minimizing Wahba's loss function are presented. The new method is compared with a conventional batch least-squares differential correction algorithm. The estimates are based on data from strapdown gyros and star trackers, simulated with varying levels of Gaussian noise for both inertially-fixed and Earth-pointing reference attitudes. Both algorithms solve for the spacecraft attitude and the gyro drift rate biases. They converge to the same estimates at the same rate for inertially-fixed attitude, but the new algorithm converges more slowly than the differential correction for Earth-pointing attitude. The slower convergence of the new method for non-zero attitude rates is believed to be due to the use of an inadequate approximation for a partial derivative matrix. The new method requires about twice the computational effort of the differential correction. Improving the approximation for the partial derivative matrix in the new method is expected to improve its convergence at the cost of increased computational effort.

  20. Sexually antagonistic polymorphism in simultaneous hermaphrodites

    Science.gov (United States)

    Jordan, Crispin Y.; Connallon, Tim

    2015-01-01

    In hermaphrodites, pleiotropic genetic tradeoffs between female and male reproductive functions can lead to sexually antagonistic (SA) selection, where individual alleles have conflicting fitness effects on each sex function. While an extensive theory of SA selection exists for dioecious species, these results have not been generalized to hermaphrodites. We develop population genetic models of SA selection in simultaneous hermaphrodites, and evaluate effects of dominance, selection on each sex function, self-fertilization, and population size, on the maintenance of polymorphism. Under obligate outcrossing, hermaphrodite model predictions converge exactly with those of dioecious populations. Self-fertilization in hermaphrodites generates three points of divergence with dioecious theory. First, opportunities for stable polymorphism decline sharply and become less sensitive to dominance with increased selfing. Second, selfing introduces an asymmetry in the relative importance of selection through male versus female reproductive functions, expands the parameter space favorable for the evolutionary invasion of female-beneficial alleles, and restricts invasion criteria for male-beneficial alleles. Finally, contrary to models of unconditionally beneficial alleles, selfing decreases genetic hitchhiking effects of invading SA alleles, and should therefore decrease these population genetic signals of SA polymorphisms. We discuss implications of SA selection in hermaphrodites, including its potential role in the evolution of “selfing syndromes”. PMID:25311368

  1. Simultaneous perturbation stochastic approximation for tidal models

    KAUST Repository

    Altaf, M.U.

    2011-05-12

    The Dutch continental shelf model (DCSM) is a shallow sea model of entire continental shelf which is used operationally in the Netherlands to forecast the storm surges in the North Sea. The forecasts are necessary to support the decision of the timely closure of the moveable storm surge barriers to protect the land. In this study, an automated model calibration method, simultaneous perturbation stochastic approximation (SPSA) is implemented for tidal calibration of the DCSM. The method uses objective function evaluations to obtain the gradient approximations. The gradient approximation for the central difference method uses only two objective function evaluation independent of the number of parameters being optimized. The calibration parameter in this study is the model bathymetry. A number of calibration experiments is performed. The effectiveness of the algorithm is evaluated in terms of the accuracy of the final results as well as the computational costs required to produce these results. In doing so, comparison is made with a traditional steepest descent method and also with a newly developed proper orthogonal decompositionbased calibration method. The main findings are: (1) The SPSA method gives comparable results to steepest descent method with little computational cost. (2) The SPSA method with little computational cost can be used to estimate large number of parameters.

  2. Simultaneous Occurrence of Dens Invaginatus and Fusion

    Directory of Open Access Journals (Sweden)

    Amit Mhapuskar

    2013-01-01

    Full Text Available Although Dens invaginatus and fusion are well-known and well established dental anomalies, they are rarely seen in supernumerary teeth. In this article, simultaneous occurrence of Dens invaginatus and fusion between maxillary lateral incisor and a supernumerary tooth is described. Dens invaginatus is clinically significant due to the possibility of the pulpal involvement; pulpitis, necrotic pulps and chronic periapical lesions are often associated with this anomaly without clinical symptoms. Fusion has a negative impact on the aesthetics, especially when it occurs in maxillary anterior teeth. It is difficult to clinically make differential diagnosis between fused teeth and geminated teeth, especially when these anomalies take place together with hypodontia or supernumerary tooth. It has been found that sequel of such teeth may result in delayed eruption, ectopic eruption or even impaction of permanent teeth; hence proper diagnosis by clinical and radiographic methods and intervention at appropriate time is of paramount importance. The accurate knowledge of variations in morphology of tooth and pulp cavity greatly assists the dentist in planning successful treatment options.

  3. Ventral hernia repair with simultaneous panniculectomy.

    Science.gov (United States)

    Hughes, K C; Weider, L; Fischer, J; Hopkins, J; Antonetti, A; Manders, E K; Dunn, E

    1996-08-01

    The repair of a ventral hernia in an obese patient presents an interesting clinical challenge. We retrospectively reviewed the charts of 55 patients who, over a 12-year period from 1983 to 1995, concomitantly underwent both ventral herniorrhaphy and panniculectomy or abdominoplasty. In six of 55 patients, the hernia was recurrent. Forty-six patients had primary abdominal wall hernias or diastasis recti. Nineteen of 55 patients had weight greater than 200 lbs. This last subset of patients had a significantly higher incidence of complications, such as seroma, cellulitis, and persistent wound drainage. In our 55 patients, we experienced only two hernia recurrences (3.6%) during an average patient follow-up of 53 weeks. From this experience, we believe that simultaneous ventral hernia repair and panniculectomy is a safe and efficacious approach to these two problems so commonly found in the obese patient. Patients with a preoperative weight greater than 200 lbs can be expected to have a greater risk of wound complications. In all cases, the wounds eventually healed with no long-term sequelae.

  4. Sci-Share: Social Networking Adapted for Distributed Scientific Collaboration Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Our goal is to develop a social networking site with novel, specially designed feature sets to enable simultaneous remote collaboration and sharing of large data...

  5. Achievable capacity limit of high performance nodes for wireless mesh networks

    CSIR Research Space (South Africa)

    Olwal, T

    2012-08-01

    Full Text Available have the ability to simultaneously communicate with many neighbours using multiple radios over orthogonal channels thereby improving effective and "online" channel utilisation. Many such networks emerging from standards such as IEEE 802.11 a...

  6. Predictive Control of Networked Multiagent Systems via Cloud Computing.

    Science.gov (United States)

    Liu, Guo-Ping

    2017-01-18

    This paper studies the design and analysis of networked multiagent predictive control systems via cloud computing. A cloud predictive control scheme for networked multiagent systems (NMASs) is proposed to achieve consensus and stability simultaneously and to compensate for network delays actively. The design of the cloud predictive controller for NMASs is detailed. The analysis of the cloud predictive control scheme gives the necessary and sufficient conditions of stability and consensus of closed-loop networked multiagent control systems. The proposed scheme is verified to characterize the dynamical behavior and control performance of NMASs through simulations. The outcome provides a foundation for the development of cooperative and coordinative control of NMASs and its applications.

  7. Information diversity in structure and dynamics of simulated neuronal networks.

    Science.gov (United States)

    Mäki-Marttunen, Tuomo; Aćimović, Jugoslava; Nykter, Matti; Kesseli, Juha; Ruohonen, Keijo; Yli-Harja, Olli; Linne, Marja-Leena

    2011-01-01

    Neuronal networks exhibit a wide diversity of structures, which contributes to the diversity of the dynamics therein. The presented work applies an information theoretic framework to simultaneously analyze structure and dynamics in neuronal networks. Information diversity within the structure and dynamics of a neuronal network is studied using the normalized compression distance. To describe the structure, a scheme for generating distance-dependent networks with identical in-degree distribution but variable strength of dependence on distance is presented. The resulting network structure classes possess differing path length and clustering coefficient distributions. In parallel, comparable realistic neuronal networks are generated with NETMORPH simulator and similar analysis is done on them. To describe the dynamics, network spike trains are simulated using different network structures and their bursting behaviors are analyzed. For the simulation of the network activity the Izhikevich model of spiking neurons is used together with the Tsodyks model of dynamical synapses. We show that the structure of the simulated neuronal networks affects the spontaneous bursting activity when measured with bursting frequency and a set of intraburst measures: the more locally connected networks produce more and longer bursts than the more random networks. The information diversity of the structure of a network is greatest in the most locally connected networks, smallest in random networks, and somewhere in between in the networks between order and disorder. As for the dynamics, the most locally connected networks and some of the in-between networks produce the most complex intraburst spike trains. The same result also holds for sparser of the two considered network densities in the case of full spike trains.

  8. Information Diversity in Structure and Dynamics of Simulated Neuronal Networks

    Directory of Open Access Journals (Sweden)

    Tuomo eMäki-Marttunen

    2011-06-01

    Full Text Available Neuronal networks exhibit a wide diversity of structures, which contributes to the diversity of the dynamics therein. The presented work applies an information theoretic framework to simultaneously analyze structure and dynamics in neuronal networks. Information diversity within the structure and dynamics of a neuronal network is studied using the normalized compression distance (NCD. To describe the structure, a scheme for generating distance-dependent networks with identical in-degree distribution but variable strength of dependence on distance is presented. The resulting network structure classes possess differing path length and clustering coefficient distributions. In parallel, comparable realistic neuronal networks are generated with NETMORPH simulator and similar analysis is done on them. To describe the dynamics, network spike trains are simulated using different network structures and their bursting behaviours are analyzed. For the simulation of the network activity the Izhikevich model of spiking neurons is used together with the Tsodyks model of dynamical synapses.We show that the structure of the simulated neuronal networks affects the spontaneous bursting activity when measured with bursting frequency and a set of intraburst measures: the more locally connected networks produce more and longer bursts than the more random networks. The information diversity of the structure of a network is greatest in the most locally connected networks, smallest in random networks, and somewhere in between in the networks between order and disorder. As for the dynamics, the most locally connected networks and some of the in-between networks produce the most complex intraburst spike trains. The same result also holds for sparser of the two considered network densities in the case of full spike trains.

  9. Integrated Chemical Systems: The Simultaneous Formation of Hybrid Nanocomposites of Iron Oxide and Organo Silsesquioxanes

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, L; Clapsaddle, B; Jr., J S; Schaefer, D; Shea, K

    2004-10-15

    A sol-gel approach for the synthesis of hybrid nanocomposites of iron oxide and bridged polysilsesquioxanes has been established. The procedures allow for the simultaneous formation of iron oxide and polysilsesquioxane networks in monolithic xerogels and aerogels. These hybrid nanocomposites are synthesized from FeCl{sub 3} {center_dot} 6H{sub 2}O and functionalized silsesquioxane monomers in a one-pot reaction using epoxides as a gelation agent. The porosity and microstructure of the materials has been determined by nitrogen porosimetry, electron microscopy and ultra small angle X-ray scattering (USAXS). The hybrid nanocomposites exhibit a uniform dispersion of both components with no evidence for phase separation at length scales > 5 nm. At this limit of resolution it is not possible to distinguish between two independent interpenetrating networks integrated at molecular length scales or a random copolymer or mixtures of both.

  10. Exploring the evolution of node neighborhoods in Dynamic Networks

    Science.gov (United States)

    Orman, Günce Keziban; Labatut, Vincent; Naskali, Ahmet Teoman

    2017-09-01

    Dynamic Networks are a popular way of modeling and studying the behavior of evolving systems. However, their analysis constitutes a relatively recent subfield of Network Science, and the number of available tools is consequently much smaller than for static networks. In this work, we propose a method specifically designed to take advantage of the longitudinal nature of dynamic networks. It characterizes each individual node by studying the evolution of its direct neighborhood, based on the assumption that the way this neighborhood changes reflects the role and position of the node in the whole network. For this purpose, we define the concept of neighborhood event, which corresponds to the various transformations such groups of nodes can undergo, and describe an algorithm for detecting such events. We demonstrate the interest of our method on three real-world networks: DBLP, LastFM and Enron. We apply frequent pattern mining to extract meaningful information from temporal sequences of neighborhood events. This results in the identification of behavioral trends emerging in the whole network, as well as the individual characterization of specific nodes. We also perform a cluster analysis, which reveals that, in all three networks, one can distinguish two types of nodes exhibiting different behaviors: a very small group of active nodes, whose neighborhood undergo diverse and frequent events, and a very large group of stable nodes.

  11. In-Situ Measurement of Power Loss for Crystalline Silicon Modules Undergoing Thermal Cycling and Mechanical Loading Stress Testing: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Spataru, Sergiu; Hacke, Pater; Sera, Dezso

    2015-09-15

    We analyze the degradation of multi-crystalline silicon photovoltaic modules undergoing simultaneous thermal, mechanical, and humidity stress testing to develop a dark environmental chamber in-situ measurement procedure for determining module power loss. From the analysis we determine three main categories of failure modes associated with the module degradation consisting of: shunting, recombination losses, increased series resistance losses, and current mismatch losses associated with a decrease in photo-current generation by removal of some cell areas due to cell fractures. Based on the analysis, we propose an in-situ module power loss monitoring procedure that relies on dark current-voltage measurements taken during the stress test, and initial and final module flash testing, to determine the power degradation characteristic of the module.

  12. Energy-saving with low dimensional network in Physarum plasmodium

    Science.gov (United States)

    Takamatsu, Atsuko; Gomi, Takuma; Endo, Tatsuya; Hirai, Tomo; Sasaki, Takato

    2017-04-01

    An adaptation process in the transportation network of Physarum plasmodium was investigated by measuring oxygen consumption during network formation. Simultaneously, the fractal dimension as a measure of network structure was estimated. Oxygen consumption decreased during the development of the network, whereas the network structure changed from a thin mesh-type to a thick dendritic type. Our data suggested that the morphology of the plasmodial network governed energy consumption; a low dimensional network in the sense of the fractal dimension reduced energy consumption. These data were supported by experimental results excluding biological reasons, such as differences in starvation/nutrient-fullness states, and aspects of mitochondrial distribution. Model analysis using the Physarum algorithm with volume conservation constraints confirmed the above findings.

  13. Synthesis and Design of Integrated Process and Water Networks

    DEFF Research Database (Denmark)

    Handani, Zainatul B.; Quaglia, Alberto; Gani, Rafiqul

    2015-01-01

    possible options with respect to the topology of the process and water networks, leading to Mixed Integer Non Linear Programming (MINLP) problem. A solution strategy to solve the multi-network problem accounts explicitly the interactions between the networks by selecting suitable technologies in order...... to transform raw materials into products and produce clean water to be reused in the process at the early stage of design. Since the connection between the process network and the wastewater treatment network is not a straight forward connection, a new converter interval is introduced in order to convert......This work presents the development of a systematic framework for a simultaneous synthesis and design of process and water networks using the superstructure-based optimization approach. In this framework, a new superstructure combining both networks is developed by attempting to consider all...

  14. Dopamine D1 signaling organizes network dynamics underlying working memory.

    Science.gov (United States)

    Roffman, Joshua L; Tanner, Alexandra S; Eryilmaz, Hamdi; Rodriguez-Thompson, Anais; Silverstein, Noah J; Ho, New Fei; Nitenson, Adam Z; Chonde, Daniel B; Greve, Douglas N; Abi-Dargham, Anissa; Buckner, Randy L; Manoach, Dara S; Rosen, Bruce R; Hooker, Jacob M; Catana, Ciprian

    2016-06-01

    Local prefrontal dopamine signaling supports working memory by tuning pyramidal neurons to task-relevant stimuli. Enabled by simultaneous positron emission tomography-magnetic resonance imaging (PET-MRI), we determined whether neuromodulatory effects of dopamine scale to the level of cortical networks and coordinate their interplay during working memory. Among network territories, mean cortical D1 receptor densities differed substantially but were strongly interrelated, suggesting cross-network regulation. Indeed, mean cortical D1 density predicted working memory-emergent decoupling of the frontoparietal and default networks, which respectively manage task-related and internal stimuli. In contrast, striatal D1 predicted opposing effects within these two networks but no between-network effects. These findings specifically link cortical dopamine signaling to network crosstalk that redirects cognitive resources to working memory, echoing neuromodulatory effects of D1 signaling on the level of cortical microcircuits.

  15. Network meta-analysis: an introduction for clinicians.

    Science.gov (United States)

    Rouse, Benjamin; Chaimani, Anna; Li, Tianjing

    2017-02-01

    Network meta-analysis is a technique for comparing multiple treatments simultaneously in a single analysis by combining direct and indirect evidence within a network of randomized controlled trials. Network meta-analysis may assist assessing the comparative effectiveness of different treatments regularly used in clinical practice and, therefore, has become attractive among clinicians. However, if proper caution is not taken in conducting and interpreting network meta-analysis, inferences might be biased. The aim of this paper is to illustrate the process of network meta-analysis with the aid of a working example on first-line medical treatment for primary open-angle glaucoma. We discuss the key assumption of network meta-analysis, as well as the unique considerations for developing appropriate research questions, conducting the literature search, abstracting data, performing qualitative and quantitative synthesis, presenting results, drawing conclusions, and reporting the findings in a network meta-analysis.

  16. Building capability through networking with investors and researchers

    DEFF Research Database (Denmark)

    Wang, Daojuan; Schøtt, Thomas

    -creation is embedded in the network around the starting entrepreneur, we expect. Co-creation benefits from networking with potential investors and with researchers and inventors, we hypothesize, and especially by networking with both investors and researchers concurrently. Co-creation is analyzed in a sample...... of startups at inception, by 9,161 entrepreneurs, surveyed in Global Entrepreneurship Monitor in 49 countries. Co-creation is found to be reduced by the entrepreneur’s networking in the private sphere of family and friends, but to be benefiting from networking in the public sphere, especially by networking...... with investors and researchers simultaneously. The findings contribute to understanding capability building as embedded in networks around the startup....

  17. Spreading of diseases through comorbidity networks across life and gender

    CERN Document Server

    Chmiel, Anna; Thurner, Stefan

    2014-01-01

    The state of health of patients is typically not characterized by a single disease alone but by multiple (comorbid) medical conditions. These comorbidities may depend strongly on age and gender. We propose a specific phenomenological comorbidity network of human diseases that is based on medical claims data of the entire population of Austria. The network is constructed from a two-layer multiplex network, where in one layer the links represent the conditional probability for a comorbidity, and in the other the links contain the respective statistical significance. We show that the network undergoes dramatic structural changes across the lifetime of patients.Disease networks for children consist of a single, strongly inter-connected cluster. During adolescence and adulthood further disease clusters emerge that are related to specific classes of diseases, such as circulatory, mental, or genitourinary disorders.For people above 65 these clusters start to merge and highly connected hubs dominate the network. Thes...

  18. Analysis of complex networks using aggressive abstraction.

    Energy Technology Data Exchange (ETDEWEB)

    Colbaugh, Richard; Glass, Kristin.; Willard, Gerald

    2008-10-01

    This paper presents a new methodology for analyzing complex networks in which the network of interest is first abstracted to a much simpler (but equivalent) representation, the required analysis is performed using the abstraction, and analytic conclusions are then mapped back to the original network and interpreted there. We begin by identifying a broad and important class of complex networks which admit abstractions that are simultaneously dramatically simplifying and property preserving we call these aggressive abstractions -- and which can therefore be analyzed using the proposed approach. We then introduce and develop two forms of aggressive abstraction: 1.) finite state abstraction, in which dynamical networks with uncountable state spaces are modeled using finite state systems, and 2.) onedimensional abstraction, whereby high dimensional network dynamics are captured in a meaningful way using a single scalar variable. In each case, the property preserving nature of the abstraction process is rigorously established and efficient algorithms are presented for computing the abstraction. The considerable potential of the proposed approach to complex networks analysis is illustrated through case studies involving vulnerability analysis of technological networks and predictive analysis for social processes.

  19. Coordinated Platoon Routing in a Metropolitan Network

    Energy Technology Data Exchange (ETDEWEB)

    Larson, Jeffrey; Munson, Todd; Sokolov, Vadim

    2016-10-10

    Platooning vehicles—connected and automated vehicles traveling with small intervehicle distances—use less fuel because of reduced aerodynamic drag. Given a network de- fined by vertex and edge sets and a set of vehicles with origin/destination nodes/times, we model and solve the combinatorial optimization problem of coordinated routing of vehicles in a manner that routes them to their destination on time while using the least amount of fuel. Common approaches decompose the platoon coordination and vehicle routing into separate problems. Our model addresses both problems simultaneously to obtain the best solution. We use modern modeling techniques and constraints implied from analyzing the platoon routing problem to address larger numbers of vehicles and larger networks than previously considered. While the numerical method used is unable to certify optimality for candidate solutions to all networks and parameters considered, we obtain excellent solutions in approximately one minute for much larger networks and vehicle sets than previously considered in the literature.

  20. Random walk centrality in interconnected multilayer networks

    CERN Document Server

    Solé-Ribalta, Albert; Gómez, Sergio; Arenas, Alex

    2015-01-01

    Real-world complex systems exhibit multiple levels of relationships. In many cases they require to be modeled as interconnected multilayer networks, characterizing interactions of several types simultaneously. It is of crucial importance in many fields, from economics to biology and from urban planning to social sciences, to identify the most (or the less) influential nodes in a network using centrality measures. However, defining the centrality of actors in interconnected complex networks is not trivial. In this paper, we rely on the tensorial formalism recently proposed to characterize and investigate this kind of complex topologies, and extend two well known random walk centrality measures, the random walk betweenness and closeness centrality, to interconnected multilayer networks. For each of the measures we provide analytical expressions that completely agree with numerically results.

  1. Social Networks and Network Structures

    Science.gov (United States)

    2006-11-01

    Research in Command & Control • Latent Semantic Analysis – Team communication – Emergent team dynamics – Shared situation awareness • Dynamic Network...requirements – Information technology requirements 28 LSA Essentials of Latent Semantic Analysis 29 Communication Analysis • Goal: Automatically monitor and

  2. The rheo-Raman microscope: Simultaneous chemical, conformational, mechanical, and microstructural measures of soft materials

    Science.gov (United States)

    Kotula, Anthony P.; Meyer, Matthew W.; De Vito, Francesca; Plog, Jan; Hight Walker, Angela R.; Migler, Kalman B.

    2016-10-01

    The design and performance of an instrument capable of simultaneous Raman spectroscopy, rheology, and optical microscopy are described. The instrument couples a Raman spectrometer and optical microscope to a rotational rheometer through an optically transparent base, and the resulting simultaneous measurements are particularly advantageous in situations where flow properties vary due to either chemical or conformational changes in molecular structure, such as in crystallization, melting, gelation, or curing processes. Instrument performance is demonstrated on two material systems that show thermal transitions. First, we perform steady state rotational tests, Raman spectroscopy, and polarized reflection microscopy during a melting transition in a cosmetic emulsion. Second, we perform small amplitude oscillatory shear measurements along with Raman spectroscopy and polarized reflection microscopy during crystallization of a high density polyethylene. The instrument can be applied to study structure-property relationships in a variety of soft materials including thermoset resins, liquid crystalline materials, colloidal suspensions undergoing sol-gel processes, and biomacromolecules. Official contribution of the National Institute of Standards and Technology; not subject to copyright in the United States.

  3. Infrared actuation-induced simultaneous reconfiguration of surface color and morphology for soft robotics.

    Science.gov (United States)

    Banisadr, Seyedali; Chen, Jian

    2017-12-13

    Cephalopods, such as cuttlefish, demonstrate remarkable adaptability to the coloration and texture of their surroundings by modulating their skin color and surface morphology simultaneously, for the purpose of adaptive camouflage and signal communication. Inspired by this unique feature of cuttlefish skins, we present a general approach to remote-controlled, smart films that undergo simultaneous changes of surface color and morphology upon infrared (IR) actuation. The smart film has a reconfigurable laminated structure that comprises an IR-responsive nanocomposite actuator layer and a mechanochromic elastomeric photonic crystal layer. Upon global or localized IR irradiation, the actuator layer exhibits fast, large, and reversible strain in the irradiated region, which causes a synergistically coupled change in the shape of the laminated film and color of the mechanochromic elastomeric photonic crystal layer in the same region. Bending and twisting deformations can be created under IR irradiation, through modulating the strain direction in the actuator layer of the laminated film. Furthermore, the laminated film has been used in a remote-controlled inchworm walker that can directly couple a color-changing skin with the robotic movements. Such remote-controlled, smart films may open up new application possibilities in soft robotics and wearable devices.

  4. The National Ecological Observatory Network

    Science.gov (United States)

    Michener, W. K.

    2006-05-01

    The National Ecological Observatory Network (NEON) is a research platform designed to advance understanding of how ecosystems and organisms respond to variations in climate and changes in land use. NEON is the first long-term ecological observatory conceived as a continental-scale network; equipped with standardized sensors, cyberinfrastructure, and data-collection protocols across the network; and designed to simultaneously address a common set of research questions and support investigator-driven ecological research in all regions of the United States. The Observatory focuses on variations in climate and land use because they are primary drivers of the Nation's environmental challenges, as identified by the National Research Council--i.e., biodiversity, biogeochemical cycles, climate change, hydroecology, infectious disease, invasive species, and land use. At the broadest scale, NEON links the complexity of climate variation to the behavior of ecological systems, a core aspect of ecological complexity. At the same time, because of the complexity of the interactions among humans and ecosystems, the network design includes NEON sites in wild, managed and urban systems within climate domains. Observatory data will also be part of a national education program designed to advance ecological science literacy through new programs and activities that develop and promote scientific ways of thinking.

  5. Coexistence in preferential attachment networks

    CERN Document Server

    Antunović, Tonći; Racz, Miklos Z

    2013-01-01

    Competition in markets is ubiquitous: cell-phone providers, computer manufacturers, and sport gear brands all vie for customers. Though several coexisting competitors are often observed in empirical data, many current theoretical models of competition on small-world networks predict a single winner taking over the majority of the network. We introduce a new model of product adoption that focuses on word-of-mouth recommendations to provide an explanation for this coexistence of competitors. The key property of our model is that customer choices evolve simultaneously with the network of customers. When a new node joins the network, it chooses neighbors according to preferential attachment, and then chooses its type based on the number of initial neighbors of each type. This can model a new cell-phone user choosing a cell-phone provider, a new student choosing a laptop, or a new athletic team member choosing a gear provider. We provide a detailed analysis of the new model; in particular, we determine the possibl...

  6. Transparency perception: the key to understanding simultaneous color contrast.

    Science.gov (United States)

    Ekroll, Vebjørn; Faul, Franz

    2013-03-01

    The well-known simultaneous color contrast effect is traditionally explained in terms of visual color constancy mechanisms correcting for the confounding influence of ambient illumination on the retinal color signal. Recent research, however, suggests that the traditional gross quantitative laws of simultaneous color contrast, which are readily compatible with this functional explanation, should be revised and replaced by others, which are not readily understandable in terms of this perspective. Here, we show that the revised laws of simultaneous color contrast are well accounted for by an alternative theory explaining the simultaneous contrast effect in terms of mechanisms subserving the perception of transparent media.

  7. Methods for simultaneous EEG-fMRI: an introductory review

    National Research Council Canada - National Science Library

    Huster, René J; Debener, Stefan; Eichele, Tom; Herrmann, Christoph S

    2012-01-01

    The simultaneous recording and analysis of electroencephalography (EEG) and fMRI data in human systems, cognitive and clinical neurosciences is rapidly evolving and has received substantial attention...

  8. Short-Term Neural Adaptation to Simultaneous Bifocal Images

    Science.gov (United States)

    Radhakrishnan, Aiswaryah; Dorronsoro, Carlos; Sawides, Lucie; Marcos, Susana

    2014-01-01

    Simultaneous vision is an increasingly used solution for the correction of presbyopia (the age-related loss of ability to focus near images). Simultaneous Vision corrections, normally delivered in the form of contact or intraocular lenses, project on the patient's retina a focused image for near vision superimposed with a degraded image for far vision, or a focused image for far vision superimposed with the defocused image of the near scene. It is expected that patients with these corrections are able to adapt to the complex Simultaneous Vision retinal images, although the mechanisms or the extent to which this happens is not known. We studied the neural adaptation to simultaneous vision by studying changes in the Natural Perceived Focus and in the Perceptual Score of image quality in subjects after exposure to Simultaneous Vision. We show that Natural Perceived Focus shifts after a brief period of adaptation to a Simultaneous Vision blur, similar to adaptation to Pure Defocus. This shift strongly correlates with the magnitude and proportion of defocus in the adapting image. The magnitude of defocus affects perceived quality of Simultaneous Vision images, with 0.5 D defocus scored lowest and beyond 1.5 D scored “sharp”. Adaptation to Simultaneous Vision shifts the Perceptual Score of these images towards higher rankings. Larger improvements occurred when testing simultaneous images with the same magnitude of defocus as the adapting images, indicating that wearing a particular bifocal correction improves the perception of images provided by that correction. PMID:24664087

  9. Short-term neural adaptation to simultaneous bifocal images.

    Directory of Open Access Journals (Sweden)

    Aiswaryah Radhakrishnan

    Full Text Available Simultaneous vision is an increasingly used solution for the correction of presbyopia (the age-related loss of ability to focus near images. Simultaneous Vision corrections, normally delivered in the form of contact or intraocular lenses, project on the patient's retina a focused image for near vision superimposed with a degraded image for far vision, or a focused image for far vision superimposed with the defocused image of the near scene. It is expected that patients with these corrections are able to adapt to the complex Simultaneous Vision retinal images, although the mechanisms or the extent to which this happens is not known. We studied the neural adaptation to simultaneous vision by studying changes in the Natural Perceived Focus and in the Perceptual Score of image quality in subjects after exposure to Simultaneous Vision. We show that Natural Perceived Focus shifts after a brief period of adaptation to a Simultaneous Vision blur, similar to adaptation to Pure Defocus. This shift strongly correlates with the magnitude and proportion of defocus in the adapting image. The magnitude of defocus affects perceived quality of Simultaneous Vision images, with 0.5 D defocus scored lowest and beyond 1.5 D scored "sharp". Adaptation to Simultaneous Vision shifts the Perceptual Score of these images towards higher rankings. Larger improvements occurred when testing simultaneous images with the same magnitude of defocus as the adapting images, indicating that wearing a particular bifocal correction improves the perception of images provided by that correction.

  10. Simultaneous gene finding in multiple genomes.

    Science.gov (United States)

    König, Stefanie; Romoth, Lars W; Gerischer, Lizzy; Stanke, Mario

    2016-11-15

    As the tree of life is populated with sequenced genomes ever more densely, the new challenge is the accurate and consistent annotation of entire clades of genomes. We address this problem with a new approach to comparative gene finding that takes a multiple genome alignment of closely related species and simultaneously predicts the location and structure of protein-coding genes in all input genomes, thereby exploiting negative selection and sequence conservation. The model prefers potential gene structures in the different genomes that are in agreement with each other, or-if not-where the exon gains and losses are plausible given the species tree. We formulate the multi-species gene finding problem as a binary labeling problem on a graph. The resulting optimization problem is NP hard, but can be efficiently approximated using a subgradient-based dual decomposition approach. The proposed method was tested on whole-genome alignments of 12 vertebrate and 12 Drosophila species. The accuracy was evaluated for human, mouse and Drosophila melanogaster and compared to competing methods. Results suggest that our method is well-suited for annotation of (a large number of) genomes of closely related species within a clade, in particular, when RNA-Seq data are available for many of the genomes. The transfer of existing annotations from one genome to another via the genome alignment is more accurate than previous approaches that are based on protein-spliced alignments, when the genomes are at close to medium distances. The method is implemented in C ++ as part of Augustus and available open source at http://bioinf.uni-greifswald.de/augustus/ CONTACT: stefaniekoenig@ymail.com or mario.stanke@uni-greifswald.deSupplementary information: Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  11. Acetaminophen attenuates lipid peroxidation in children undergoing cardiopulmonary bypass.

    Science.gov (United States)

    Simpson, Scott A; Zaccagni, Hayden; Bichell, David P; Christian, Karla G; Mettler, Bret A; Donahue, Brian S; Roberts, L Jackson; Pretorius, Mias

    2014-07-01

    Hemolysis, occurring during cardiopulmonary bypass, is associated with lipid peroxidation and postoperative acute kidney injury. Acetaminophen inhibits lipid peroxidation catalyzed by hemeproteins and in an animal model attenuated rhabdomyolysis-induced acute kidney injury. This pilot study tests the hypothesis that acetaminophen attenuates lipid peroxidation in children undergoing cardiopulmonary bypass. Single-center prospective randomized double-blinded study. University-affiliated pediatric hospital. Thirty children undergoing elective surgical correction of a congenital heart defect. Patients were randomized to acetaminophen (OFIRMEV [acetaminophen] injection; Cadence Pharmaceuticals, San Diego, CA) or placebo every 6 hours for four doses starting before the onset of cardiopulmonary bypass. Markers of hemolysis, lipid peroxidation (isofurans and F2-isoprostanes), and acute kidney injury were measured throughout the perioperative period. Cardiopulmonary bypass was associated with a significant increase in free hemoglobin (from a prebypass level of 9.8 ± 6.2 mg/dL to a peak of 201.5 ± 42.6 mg/dL postbypass). Plasma and urine isofuran and F2-isoprostane concentrations increased significantly during surgery. The magnitude of increase in plasma isofurans was greater than the magnitude in increase in plasma F2-isoprostanes. Acetaminophen attenuated the increase in plasma isofurans compared with placebo (p = 0.02 for effect of study drug). There was no significant effect of acetaminophen on plasma F2-isoprostanes or urinary makers of lipid peroxidation. Acetaminophen did not affect postoperative creatinine, urinary neutrophil gelatinase-associated lipocalin, or prevalence of acute kidney injury. Cardiopulmonary bypass in children is associated with hemolysis and lipid peroxidation. Acetaminophen attenuated the increase in plasma isofuran concentrations. Future studies are needed to establish whether other therapies that attenuate or prevent the effects of free

  12. Perioperative physiotherapy in patients undergoing lung cancer resection.

    Science.gov (United States)

    Rodriguez-Larrad, Ana; Lascurain-Aguirrebena, Ion; Abecia-Inchaurregui, Luis Carlos; Seco, Jesús

    2014-08-01

    Physiotherapy is considered an important component of the perioperative period of lung resection surgery. A systematic review was conducted to assess evidence for the effectiveness of different physiotherapy interventions in patients undergoing lung cancer resection surgery. Online literature databases [Medline, the Cochrane Central Register of Controlled Trials (CENTRAL), EMBASE, SCOPUS, PEDro and CINAHL] were searched up until June 2013. Studies were included if they were randomized controlled trials, compared 2 or more perioperative physiotherapy interventions or compared one intervention with no intervention, included only patients undergoing pulmonary resection for lung cancer and assessed at least 2 or more of the following variables: functional capacity parameters, postoperative pulmonary complications or length of hospital stay. Reviews and meta-analyses were excluded. Eight studies were selected for inclusion in this review. They included a total of 599 patients. Seven of the studies were identified as having a low risk of bias. Two studies assessed preoperative interventions, 4 postoperative interventions and the remaining 2 investigated the efficacy of interventions that were started preoperatively and then continued after surgery. The substantial heterogeneity in the interventions across the studies meant that it was not possible to conduct a meta-analysis. The most important finding of this systematic review is that presurgical interventions based on moderate-intense aerobic exercise in patients undergoing lung resection for lung cancer improve functional capacity and reduce postoperative morbidity, whereas interventions performed only during the postoperative period do not seem to reduce postoperative pulmonary complications or length of hospital stay. Nevertheless, no firm conclusions can be drawn because of the heterogeneity of the studies included. Further research into the efficacy and effectiveness of perioperative respiratory physiotherapy in

  13. Survival outcomes in elderly men undergoing radical prostatectomy in Australia.

    Science.gov (United States)

    Ranasinghe, Weranja; Wang, Luke L; Persad, Raj; Bolton, Damien; Lawrentschuk, Nathan; Sengupta, Shomik

    2017-09-18

    To investigate the outcomes of patients older than 75 years of age in Victoria undergoing radical prostatectomy for prostate cancer. Data on all men undergoing radical prostatectomy in Victoria between 1 January 2004 and 31 December 2014 were obtained from the Victorian Cancer Registry. Tumour characteristics including Gleason grade, stage of disease and cause of death were obtained. Statistical analysis was performed using chi-squared test, Cox proportional hazards method and Kaplan-Meier analysis. A total of 14 686 men underwent radical prostatectomy during the defined period, with a median follow-up of 58 months. Of these, 332 were men over the age of 75. All parameters are comparisons between patients >75 years of age and men 75 years had a higher proportion of Gleason grade ≥8 disease (16.6% versus 11.4%, P 75 years had lower rates of 5- and 10-year overall survival (67.3% versus 96.3% and 27.7% versus 89.1%) and lower rates of 5- and 10-year prostate cancer-specific survival (96.2% versus 99.3% and 94.3% versus 97.4%), respectively. Age was an independent risk factor for prostate cancer specific and overall mortality on multivariate analysis (hazard ratio 1.49, 95% confidence interval 1.32-1.68; P < 0.001 and hazard ratio 4.26, 95% confidence interval 2.15-8.42; P < 0.001), when adjusted for stage and grade. Older men undergoing radical prostatectomy in Victoria had higher-grade disease but similar stage. Age was an independent risk factor for worse prostate cancer-specific and overall survival. © 2017 Royal Australasian College of Surgeons.

  14. The role of eptifibatide in patients undergoing percutaneous coronary intervention.

    Science.gov (United States)

    Zeymer, Uwe

    2007-06-01

    Glycoprotein (GP) IIb/IIIa receptor antagonists inhibit the binding of ligands to activated platelet GP IIb/IIIa receptors and, therefore, prevent the formation of platelet thrombi. They have been extensively studied in patients undergoing percutaneous coronary intervention (PCI). Eptifibatide, one of the approved GP IIb/IIIa inhibitors, is a small heptapeptide that is highly selective and rapidly dissociates from its receptor after cessation of therapy. In clinical studies, concomitant administration of eptifibatide in patients undergoing elective PCI reduced thrombotic complications in the IMPACT-II (Integrilin to Minimize Platelet Aggregation and Prevent Coronary Thrombosis II) and ESPRIT (Enhanced Suppression of the Platelet IIb/IIIa Receptor with Integrilin Therapy) trials. In the PURSUIT (Platelet Glycoprotein IIb/IIIa in Unstable Angina: Receptor Suppression Using Integrilin Therapy) trial, which included 10,948 patients with non-ST-elevation acute coronary syndromes, eptifibatide significantly reduced the primary end point of death and non-fatal myocardial infarction at 30 days compared with placebo. In patients with ST-segment elevation myocardial infarction (STEMI), eptifibatide has been studied as adjunct to primary PCI and improved epicardial flow and tissue reperfusion. Studies are now evaluating eptifibatide in high-risk patients with non-ST elevation acute coronary syndromes (NSTE-ACS) and a planned early invasive strategy in the EARLY-ACS (Eptifibatide Administration prior to Diagnostic Catherization and Revascularization to Limit Myocardial Necrosis in Acute Coronary Syndrome) trial and in patients with primary PCI for STEMI in comparison to abciximab in the EVA-AMI (Eptifibatide versus Abciximab in Primary PCI for Acute Myocardial Infarction) trial. After the completion of these trials, the value of etifibatide in patients undergoing PCI in different indications can be determined.

  15. Cold agglutinins in patients undergoing cardiac surgery requiring cardiopulmonary bypass.

    Science.gov (United States)

    Barbara, David W; Mauermann, William J; Neal, James R; Abel, Martin D; Schaff, Hartzell V; Winters, Jeffrey L

    2013-09-01

    Cold agglutinins (CA) are circulating autoantibodies present in most humans. They are active below normal body temperatures. Cold hemagglutinin disease involves the presence of CA sufficiently active at temperatures in the periphery to produce hemolysis or agglutination. Systemic hypothermia and cold cardioplegia may result in agglutination or hemolysis. We reviewed the experience of a large referral center in managing patients with CA and cold hemagglutinin disease undergoing cardiac surgery requiring cardiopulmonary bypass. The electronic medical records from 2002 to 2010 were searched to identify patients with CA or cold hemagglutinin disease who underwent cardiac surgery requiring cardiopulmonary bypass. Information related to preoperative CA testing and treatment, surgery, cardiopulmonary bypass, postoperative complications, and mortality was recorded. Sixteen patients underwent 19 procedures requiring cardiopulmonary bypass. Six patients had cold hemagglutinin disease. The identification of CA was made intraoperatively in 3 patients. One patient underwent preoperative plasma exchange. Cold blood cardioplegia was used in 2 of 16 procedures using cardioplegia, with the remaining using warmer blood cardioplegia. The lowest recorded intraoperative core temperature was less than 34 °C in 1 case. CA-related postoperative hemolysis requiring transfusion was present in 1 patient, which was resolved with active warming. No patient had evidence of permanent myocardial dysfunction, had a neurologic event, required dialysis, or died within 30 days. All patients with CA/cold hemagglutinin disease at the Mayo Clinic College of Medicine safely underwent cardiac surgery without major adverse morbidity or mortality. Patients with CA but without evidence of cold hemagglutinin disease can safely undergo normothermic cardiopulmonary bypass at 37°C and warm cardioplegia without further testing. Patients with cold hemagglutinin disease should undergo laboratory testing including

  16. [The health of adults undergoing an eviction process].

    Science.gov (United States)

    Bolívar Muñoz, Julia; Bernal Solano, Mariola; Mateo Rodríguez, Inmaculada; Daponte Codina, Antonio; Escudero Espinosa, Cecilia; Sánchez Cantalejo, Carmen; González Usera, Isis; Robles Ortega, Humbelina; Mata Martín, José Luis; Fernández Santaella, M Carmen; Vila Castellar, Jaime

    2016-01-01

    To analyze perceived health status and other health-related indicators in the adult population in Granada (Spain) undergoing an eviction process from their homes, whether rented or owned, in comparison with health indicators in the general adult population in Andalusia. A cross-sectional survey was administered by trained staff. The survey included instruments from the Andalusian Health Survey 2011 for measuring variables related to physical and mental health, as well as health-related habits. We compared the results with those obtained from the Andalusian general population through the Andalusian Health Survey. A bivariate analysis using the χ2 test and a multivariate logistic regression analysis were conducted. We obtained a total sample of 205 people in the process of eviction. A total of 59.5% (n=122) were women, and 40.5% (n=83) were men. Participants were more likely to have poor health (odds ratio [OR]: 12.63, 95% confidence interval [95%CI]: 8.74-18.27), have cardiovascular diseases (OR: 3.08; 95%CI: 1.54- 6.16), or to smoke (OR: 1.68; 95% CI: 1.21-2.33) compared with the Andalusian general population. Most of the health indicators analyzed showed a worse outcome for women undergoing an eviction process. Our results suggest that, in the current context of economic crisis, people undergoing a process of eviction in Granada and its metropolitan area show poorer health than the Andalusian general population. Further research is needed on health and evictions from different methodological approaches, for a better understanding of the topic. Copyright © 2015 SESPAS. Published by Elsevier Espana. All rights reserved.

  17. Platelet reactivity in patients undergoing transcatheter aortic valve implantation.

    Science.gov (United States)

    Orvin, Katia; Eisen, Alon; Perl, Leor; Zemer-Wassercug, Noa; Codner, Pablo; Assali, Abid; Vaknin-Assa, Hana; Lev, Eli I; Kornowski, Ran

    2016-07-01

    Thromboembolic events, primarily stroke, might complicate transcatheter aortic-valve implantation (TAVI) procedures in 3-5 % of cases. Thus, it is common to administer aspirin and clopidogrel pharmacotherapy for 3-6 months following TAVI in order to prevent those events. The biologic response to the dual anti platelet treatment (DAPT) is heterogeneous, e.g. low response, known as high on treatment platelet reactivity (HTPR) may be associated with adverse thromboembolic events. Little is known about the prevalence of HTPR among patients undergoing TAVI. To assess the variability in response and rates of residual platelet reactivity in patients undergoing TAVI. We examined platelet reactivity in response to clopidogrel and aspirin in 40 consecutive patients (mean age 81.7 ± 6.5 years, 66.7 % women) who underwent successful TAVI using the VerifyNow P2Y12 assay and the multiple electrode aggregometry assay (Multiplate analyzer) in response to adenosine diphosphate and arachidonic acid respectively, at different time points before and following TAVI. Before TAVI, the majority of patients were on antiplatelet therapy (68.5 % aspirin, 12.5 % clopidogrel, 12.5 % DAPT). Following the procedure all patients were on DAPT or clopidogrel and warfarin. Among analyzed patients, 41 % had HTPR for clopidogrel and 12.5 % for aspirin at baseline, which did not significantly change 1-month following the procedure (p = 0.81 and p  = 0.33, respectively). In conclusion, patients undergoing TAVI for severe aortic stenosis and treated with DAPT have high rates of residual platelet reactivity during the peri-procedural period and up to 1-month thereafter. These findings may have clinical implications for the anti-platelet management of TAVI patients.

  18. Hospital costs associated with smoking in veterans undergoing general surgery.

    Science.gov (United States)

    Kamath, Aparna S; Vaughan Sarrazin, Mary; Vander Weg, Mark W; Cai, Xueya; Cullen, Joseph; Katz, David A

    2012-06-01

    Approximately 30% of patients undergoing elective general surgery smoke cigarettes. The association between smoking status and hospital costs in general surgery patients is unknown. The objectives of this study were to compare total inpatient costs in current smokers, former smokers, and never smokers undergoing general surgical procedures in Veterans Affairs (VA) hospitals; and to determine whether the relationship between smoking and cost is mediated by postoperative complications. Patients undergoing general surgery during the period of October 1, 2005 to September 30, 2006 were identified in the VA Surgical Quality Improvement Program (VASQIP) data set. Inpatient costs were extracted from the VA Decision Support System (DSS). Relative surgical costs (incurred during index hospitalization and within 30 days of operation) for current and former smokers relative to never smokers, and possible mediators of the association between smoking status and cost were estimated using generalized linear regression models. Models were adjusted for preoperative and operative variables, accounting for clustering of costs at the hospital level. Of the 14,853 general surgical patients, 34% were current smokers, 39% were former smokers, and 27% were never smokers. After controlling for patient covariates, current smokers had significantly higher costs compared with never smokers: relative cost was 1.04 (95% Cl 1.00 to 1.07; p = 0.04); relative costs for former smokers did not differ significantly from those of never smokers: 1.02 (95% Cl 0.99 to 1.06; p = 0.14). The relationship between smoking and hospital costs for current smokers was partially mediated by postoperative respiratory complications. These findings complement emerging evidence recommending effective smoking cessation programs in general surgical patients and provide an estimate of the potential savings that could be accrued during the preoperative period. Published by Elsevier Inc.

  19. Spinal Anesthesia in Elderly Patients Undergoing Lumbar Spine Surgery.

    Science.gov (United States)

    Lessing, Noah L; Edwards, Charles C; Brown, Charles H; Ledford, Emily C; Dean, Clayton L; Lin, Charles; Edwards, Charles C

    2017-03-01

    Spinal anesthesia is increasingly viewed as a reasonable alternative to general anesthesia for lumbar spine surgery. However, the results of spinal anesthesia in elderly patients undergoing lumbar spine decompression and combined decompression and fusion procedures are limited in the literature. The aim of this study was to report a single institution's experience using spinal anesthesia in elderly patients undergoing lumbar spine surgery. A retrospective review was conducted using a prospectively collected database of consecutive lumbar spine surgeries performed under spinal anesthesia in patients 70 years or older at a single center between December 2013 and October 2015. A total of 56 patients were included in the study; 27 patients (48%) underwent lumbar decompression and 29 patients (52%) underwent combined decompression and fusion procedures. Mean operative time was 101 minutes (range, 30-210 minutes), and mean operative blood loss was 187 mL (range, 20-700 mL). Mean maximum inpatient postoperative visual analog scale score was 6.2 (range, 1-10). Nausea occurred in 21% (12 of 56) of the patients. Mean length of stay was 2.4 days (range, 1-6 days). No mortality, stroke, permanent loss of function, or pulmonary embolism occurred. None of the cases required conversion to general anesthesia. All of the patients were ambulatory on either the day of the surgery or the next morning. These results demonstrate that spinal anesthesia is a viable method of anesthesia for patients 70 years and older undergoing lumbar spine surgery. They also demonstrate the safety of this method for patients older than 84 years and for surgeries lasting up to 3½ hours. [Orthopedics. 2017; 40(2):e317-e322.]. Copyright 2016, SLACK Incorporated.

  20. Processing of signals from an ion-elective electrode array by a neural network

    NARCIS (Netherlands)

    Bos, M.; Bos, A.; van der Linden, W.E.

    1990-01-01

    Neural network software is described for processing the signals of arrays of ion-selective electrodes. The performance of the software was tested in the simultaneous determination of calcium and copper(II) ions in binary mixtures of copper(II) nitrate and calcium chloride and the simultaneous

  1. Introduction to neural networks

    CERN Document Server

    James, Frederick E

    1994-02-02

    1. Introduction and overview of Artificial Neural Networks. 2,3. The Feed-forward Network as an inverse Problem, and results on the computational complexity of network training. 4.Physics applications of neural networks.

  2. Salivary function in patients with chronic renal failure undergoing hemodialysis

    Energy Technology Data Exchange (ETDEWEB)

    Kaya, M.; Cermik, T.F.; Uestuen, F.; Sen, S.; Berkarda, S. [Trakya Univ., Edirne (Turkey). Medical Faculty

    2002-04-01

    The aim of this study was to evaluate the changes in salivary gland function in patients with chronic renal failure (CRF) undergoing hemodialysis. The group consisted of 23 patients with CRF (13 female, 10 male; mean age: 40{+-}13 yr) and 14 healthy control subjects (mean age: 40{+-}13 yr). All underwent dynamic salivary gland scintigraphy with gustatory stimulation. After intravenous administration of {sup 99m}Tc pertechnetate, first, perfusion images at 2 seconds per frame were acquired for 1 minute, then dynamic images at 1 minute per frame were acquired for 45 minutes. At 30 minutes after injection , 10 ml lemon juice was given for 15 minutes as a gustatory stimulus. We obtained time-activity curves derived from regions of interest centered over the four major salivary glands. The following functional indices were calculated for each gland: the time of maximum radioactivity (T{sub max}) for the prestimulated period, the time of minimum radioactivity (T{sub min}), as an indicator of velocity of secretion after stimulation, and the Lem E{sub 5}% value as an indicator of the secretion function. When the patients with CRF undergoing hemodialysis were compared to the controls, there were statistically significant differences in T{sub max}, T{sub min} and Lem E{sub 5}% values for bilateral parotid glands, and T{sub min} values for bilateral submandibular glands (p<0.05), there were no statistically significant differences in T{sub max} and Lem E{sub 5}% values for bilateral submandibular glands. There were also significant differences in T{sub max} and Lem E{sub 5}% values for bilateral parotid glands between mild oral problems and severe oral problems in patients with CRF (undergoing hemodialysis). In this study, prolonged T{sub max} and T{sub min} values, and decreased Lem E{sub 5}% values for parotid glands and prolonged T{sub min} values for submandibular glands on salivary scintigraphy pointed out decreased parenchymatous and excretory function in patients with

  3. Composite network using PLC and SCM technologies

    Science.gov (United States)

    Tsuchiya, Toshiyuki; Ohno, Kazuyoshi; Shiraishi, Takashi; Okada, Masaya

    1993-02-01

    The study of integrated opto-electrical circuits has lead to the evolution of silica-based planer lightwave circuit (PLC) technology. PLC technology can be applied to the filtering of optical signals. Optical filters for AM-FDM signals that use the subcarrier multiplexing (SCM) technique can access two optical carrier wavelengths simultaneously, and can be used with point-to-multipoint wiring using coaxial cable to home videos. The use of optical fibers in subscriber networks has become a priority in telecommunications and video transmissions. In our network, the optical network unit (ONU) which is installed in an outside plant is designed so that three kinds of optical fiber systems are terminated simultaneously. They are for the video fiber backbone, personal communications and narrow band ISDN. The radius of the service area offered by the ONU is a few hundred meters. This network configuration is suitable for powering and operation, administration and maintenance (OA&M) from the viewpoint of feeder fiber network design.

  4. Structured Tracking for Safety, Security, and Privacy: Algorithms for Fusing Noisy Estimates from Sensor, Robot, and Camera Networks

    Science.gov (United States)

    2009-07-23

    Data gathering tours in sensor networks,” in Proceedings on Information Processing in Sensor Networks (IPSN), April 2006. [129] T. Meltzer, C...Shrobe, and A. Grue , “Simultaneous localization, calibration, and tracking in an ad hoc sensor network,” in Pro- ceedings of Information processing in

  5. Network gravity

    Science.gov (United States)

    Lombard, John

    2017-01-01

    We introduce the construction of a new framework for probing discrete emergent geometry and boundary-boundary observables based on a fundamentally a-dimensional underlying network structure. Using a gravitationally motivated action with Forman weighted combinatorial curvatures and simplicial volumes relying on a decomposition of an abstract simplicial complex into realized embeddings of proper skeletons, we demonstrate properties such as a minimal volume-scale cutoff, the necessity of a term playing the role of a positive definite cosmological constant as a regulator for nondegenerate geometries, and naturally emergent simplicial structures from Metropolis network evolution simulations with no restrictions on attachment rules or regular building blocks. We see emergent properties which echo results from both the spinfoam formalism and causal dynamical triangulations in quantum gravity, and provide analytical and numerical results to support the analogy. We conclude with a summary of open questions and intent for future work in developing the program.

  6. Neural Networks

    Directory of Open Access Journals (Sweden)

    Schwindling Jerome

    2010-04-01

    Full Text Available This course presents an overview of the concepts of the neural networks and their aplication in the framework of High energy physics analyses. After a brief introduction on the concept of neural networks, the concept is explained in the frame of neuro-biology, introducing the concept of multi-layer perceptron, learning and their use as data classifer. The concept is then presented in a second part using in more details the mathematical approach focussing on typical use cases faced in particle physics. Finally, the last part presents the best way to use such statistical tools in view of event classifers, putting the emphasis on the setup of the multi-layer perceptron. The full article (15 p. corresponding to this lecture is written in french and is provided in the proceedings of the book SOS 2008.

  7. Simultaneous EEG-fMRI at ultra-high field: artifact prevention and safety assessment.

    Science.gov (United States)

    Jorge, João; Grouiller, Frédéric; Ipek, Özlem; Stoermer, Robert; Michel, Christoph M; Figueiredo, Patrícia; van der Zwaag, Wietske; Gruetter, Rolf

    2015-01-15

    The simultaneous recording of scalp electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) can provide unique insights into the dynamics of human brain function, and the increased functional sensitivity offered by ultra-high field fMRI opens exciting perspectives for the future of this multimodal approach. However, simultaneous recordings are susceptible to various types of artifacts, many of which scale with magnetic field strength and can seriously compromise both EEG and fMRI data quality in recordings above 3T. The aim of the present study was to implement and characterize an optimized setup for simultaneous EEG-fMRI in humans at 7 T. The effects of EEG cable length and geometry for signal transmission between the cap and amplifiers were assessed in a phantom model, with specific attention to noise contributions from the MR scanner coldheads. Cable shortening (down to 12 cm from cap to amplifiers) and bundling effectively reduced environment noise by up to 84% in average power and 91% in inter-channel power variability. Subject safety was assessed and confirmed via numerical simulations of RF power distribution and temperature measurements on a phantom model, building on the limited existing literature at ultra-high field. MRI data degradation effects due to the EEG system were characterized via B0 and B1(+) field mapping on a human volunteer, demonstrating important, although not prohibitive, B1 disruption effects. With the optimized setup, simultaneous EEG-fMRI acquisitions were performed on 5 healthy volunteers undergoing two visual paradigms: an eyes-open/eyes-closed task, and a visual evoked potential (VEP) paradigm using reversing-checkerboard stimulation. EEG data exhibited clear occipital alpha modulation and average VEPs, respectively, with concomitant BOLD signal changes. On a single-trial level, alpha power variations could be observed with relative confidence on all trials; VEP detection was more limited, although

  8. Network Frontier Workshop 2013

    Science.gov (United States)

    2014-11-11

    networks, biological networks, cognitive and semantic networks and social networks. This field has received a major boost caused by the availability of huge...networks, which require new ways of thinking about the world. Part of the new cognition is provided by the fractional calculus description of temporal...structures in a wide range of examples—including road networks in large urban areas, a rabbit warren, a dolphin social network, a European interbank network

  9. Linear network theory

    CERN Document Server

    Sander, K F

    1964-01-01

    Linear Network Theory covers the significant algebraic aspect of network theory, with minimal reference to practical circuits. The book begins the presentation of network analysis with the exposition of networks containing resistances only, and follows it up with a discussion of networks involving inductance and capacity by way of the differential equations. Classification and description of certain networks, equivalent networks, filter circuits, and network functions are also covered. Electrical engineers, technicians, electronics engineers, electricians, and students learning the intricacies

  10. Surface Networks

    OpenAIRE

    Kostrikov, Ilya; Bruna, Joan; Panozzo, Daniele; Zorin, Denis

    2017-01-01

    We study data-driven representations for three-dimensional triangle meshes, which are one of the prevalent objects used to represent 3D geometry. Recent works have developed models that exploit the intrinsic geometry of manifolds and graphs, namely the Graph Neural Networks (GNNs) and its spectral variants, which learn from the local metric tensor via the Laplacian operator. Despite offering excellent sample complexity and built-in invariances, intrinsic geometry alone is invariant to isometr...

  11. Loss Networks

    OpenAIRE

    Kelly, F. P.

    1991-01-01

    This paper describes work on the stochastic modelling of loss networks. Such systems have long been of interest to telephone engineers and are becoming increasingly important as models of computer and information systems. Throughout the century problems from this field have provided an impetus to the development of probability theory, pure and applied. This paper provides an introduction to the area and a review of recent work.

  12. Evaluation of diagnostic performance of whole-body simultaneous PET/MRI in pediatric lymphoma.

    Science.gov (United States)

    Ponisio, Maria Rosana; McConathy, Jonathan; Laforest, Richard; Khanna, Geetika

    2016-08-01

    Whole-body (18)F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) is the standard of care for lymphoma. Simultaneous PET/MRI (magnetic resonance imaging) is a promising new modality that combines the metabolic information of PET with superior soft-tissue resolution and functional imaging capabilities of MRI while decreasing radiation dose. There is limited information on the clinical performance of PET/MRI in the pediatric setting. This study evaluated the feasibility, dosimetry, and qualitative and quantitative diagnostic performance of simultaneous whole-body FDG-PET/MRI in children with lymphoma compared to PET/CT. Children with lymphoma undergoing standard of care FDG-PET/CT were prospectively recruited for PET/MRI performed immediately after the PET/CT. Images were evaluated for quality, lesion detection and anatomical localization of FDG uptake. Maximum and mean standardized uptake values (SUVmax/mean) of normal organs and SUVmax of the most FDG-avid lesions were measured for PET/MRI and PET/CT. Estimation of radiation exposure was calculated using specific age-related factors. Nine PET/MRI scans were performed in eight patients (mean age: 15.3 years). The mean time interval between PET/CT and PET/MRI was 51 ± 10 min. Both the PET/CT and PET/MRI exams had good image quality and alignment with complete (9/9) concordance in response assessment. The SUVs from PET/MRI and PET/CT were highly correlated for normal organs (SUVmean r(2): 0.88, Pcompared with PET/CT. Simultaneous whole-body PET/MRI is clinically feasible in pediatric lymphoma. PET/MRI performance is comparable to PET/CT for lesion detection and SUV measurements. Replacement of PET/CT with PET/MRI can significantly decrease radiation dose from diagnostic imaging in children.

  13. Systemic Safety of Liposomal Bupivacaine in Simultaneous Bilateral Total Knee Arthroplasty.

    Science.gov (United States)

    Springer, Bryan D; Mason, J Bohannon; Odum, Susan M

    2017-08-01

    Intraoperative periarticular injections (PAIs) with local anesthetic are an important component of multimodal pain control in total joint arthroplasty. Liposomal bupivacaine is an extended-release formulation of bupivacaine designed to provide extended pain relief, approved for use in a single surgical site. The systemic safety profile for use in simultaneous bilateral TKA (bTKA) with a full dose in each knee has not been evaluated. The purpose of this study was to determine the safety and pharmacokinetics of bilateral full-dose PAI liposomal bupivacaine in the blood collected in patients undergoing simultaneous bTKA. In this prospective study, patients had an identical PAI consisting of 20 cc of liposomal bupivacaine (266 mg), 30 cc of 0.25% bupivacaine (75 mg) with epinephrine, and 10 cc of normal saline injected into each knee during bTKA. Blood samples were collected at predefined intervals until patient discharge. No exogenous bupivacaine was administered. Pharmacokinetic evaluations were subsequently performed and compared to bupivacaine toxicity levels. Patients were monitored for adverse events related to anesthetic toxicity (cardiac and neurologic). Fifteen patients (mean age, 60.7 years; range, 57-64 years) were enrolled in the study. The mean peak level (Cmax) was 0.8 μg/mL (range, 0.4-1.2 μg/mL). All patients were well below the reported systemic cardiac and toxicity levels reported as 2-4 μg/mL. There were no reported cardiac and neurotoxic events in any patients. The use of full-dose PAI with liposomal bupivacaine placed into each knee during simultaneous bTKA is safe with systemic bupivacaine levels well below reported cardiac and neurotoxic levels. Copyright © 2017 Elsevier Inc. All rights reserved.

  14. Evolution of Controllability in Interbank Networks

    Science.gov (United States)

    Delpini, Danilo; Battiston, Stefano; Riccaboni, Massimo; Gabbi, Giampaolo; Pammolli, Fabio; Caldarelli, Guido

    2013-04-01

    The Statistical Physics of Complex Networks has recently provided new theoretical tools for policy makers. Here we extend the notion of network controllability to detect the financial institutions, i.e. the drivers, that are most crucial to the functioning of an interbank market. The system we investigate is a paradigmatic case study for complex networks since it undergoes dramatic structural changes over time and links among nodes can be observed at several time scales. We find a scale-free decay of the fraction of drivers with increasing time resolution, implying that policies have to be adjusted to the time scales in order to be effective. Moreover, drivers are often not the most highly connected ``hub'' institutions, nor the largest lenders, contrary to the results of other studies. Our findings contribute quantitative indicators which can support regulators in developing more effective supervision and intervention policies.

  15. A Hub Location Problem with Fully Interconnected Backbone and Access Networks

    DEFF Research Database (Denmark)

    Thomadsen, Tommy; Larsen, Jesper

    2007-01-01

    This paper considers the design of two-layered fully interconnected networks. A two-layered network consists of clusters of nodes, each defining an access network and a backbone network. We consider the integrated problem of determining the access networks and the backbone network simultaneously...... problems. We obtain superior bounds using the column generation approach than with the linear programming relaxation. The column generation method is therefore developed into an exact approach using the Branch-and-Price framework. With this approach we are able to solve problems consisting of up to 25...

  16. A Distributed Network Mobility Management Scheme for Hierarchical Mobile IPv6 Networks

    Science.gov (United States)

    Kawano, Keita; Kinoshita, Kazuhiko; Yamai, Nariyoshi

    Route optimization for network mobility is a key technique for providing a node in a mobile network (Mobile Network Node or MNN) with high quality broadband communications. Many schemes adding route optimization function to Network Mobility (NEMO) Basic Support protocol, the standardized network mobility management protocol from the IETF nemo working group, have already been proposed in recent years. One such scheme, a scheme using Hierarchical Mobile IPv6 (HMIPv6) aims to overcome micromobility management issues as well by applying a mechanism based on HMIPv6. The traditional scheme, however, suffers from a significant number of signaling messages as the number of MNNs and/or the number of their Correspondent Nodes (CNs) increase, because many messages notifying the MNNs' Home Agents (HAMNNs) and the CNs of the mobile network's movement are generated simultaneously each time the mobile network moves to the domain of another micromobility management router (Mobility Anchor Point or MAP). This paper proposes a scheme to overcome this problem. Our scheme reduces the number of signaling messages generated at the same time by managing the mobility of MNNs using multiple MAPs distributed within a network for load sharing. The results of simulation experiments show that our scheme works efficiently compared to the traditional scheme when a mobile network has many MNNs and/or these MNNs communicate with many CNs.

  17. Transpolar arcs observed simultaneously in both hemispheres

    Science.gov (United States)

    Carter, J. A.; Milan, S. E.; Fear, R. C.; Walach, M.-T.; Harrison, Z. A.; Paxton, L. J.; Hubert, B.

    2017-06-01

    Two coexisting transpolar arcs are observed on 31 August 2005. We track the formation and motion of the arcs in both the Northern and Southern Hemispheres, using data from two independent satellites (Imager for Magnetopause to Aurora Global Exploration and a Defence Meteorological Satellite Program satellite). The observations are supported by supplementary ground-based ionospheric convection data from the Super Dual Auroral Radar Network. The two arcs form during a period of northward interplanetary magnetic field. Following a change in the direction of the interplanetary magnetic field BY component from negative to positive, the dawnside arc traverses the polar cap to the duskside in the Northern Hemisphere. Over the same time period and in the Southern Hemisphere, the duskside arc traverses the polar cap to the dawnside. A complex magnetic field line topology resulting in the coexistence of two tongues of closed field lines protruding into the otherwise open polar cap is implied. We discuss these observations in terms of magnetic conjugacy and a model of transpolar arcs formation.

  18. Are children undergoing cardiac surgery receiving antibiotics at subtherapeutic levels?

    Science.gov (United States)

    Huang, Jennifer H; Sunstrom, Rachel; Munar, Myrna Y; Cherala, Ganesh; Legg, Arthur; Olyeai, Ali J; Langley, Stephen M

    2014-10-01

    Perioperative antibiotics have decreased-but not eradicated-postoperative infections. In patients undergoing cardiac surgery with cardiopulmonary bypass, the dilutional effect of the priming and any additional volume given during the procedure may lead to subtherapeutic antibiotic levels. Our aim was to determine if children undergoing cardiac surgery with cardiopulmonary bypass receive perioperative antibiotics at subtherapeutic levels. Using published pharmacokinetic data on cefuroxime, we developed a computer simulation model to generate a nomogram predicting patients at risk for subtherapeutic cefuroxime levels based on time from initial dosing and additional volume given. A computer-generated 1-compartment pharmacokinetic model was created to predict cefuroxime plasma levels over time for patients of all weights and additional volumes given for both a 25- and 50-mg/kg intravenous dose. For example, following a 25-mg/kg dose, a patient receiving an additional volume of 275 mL/kg is predicted to be subtherapeutic (antibiotics in patients receiving large additional volumes during cardiac surgeries. This rational approach to perioperative antibiotic dosing may result in a reduction in postoperative infection in this vulnerable patient population. Copyright © 2014 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.

  19. Knowledge of electromyography (EMG) in patients undergoing EMG examinations.

    Science.gov (United States)

    Mondelli, Mauro; Aretini, Alessandro; Greco, Giuseppe

    2014-01-01

    The aim of this study was to evaluate knowledge of electromyography (EMG) in patients undergoing the procedure. In one year, 1,586 consecutive patients (mean age 56 years; 58.8% women) were admitted to two EMG labs to undergo EMG for the first time. The patients found to be "informed" about the how an EMG examination is performed and about the purpose of EMG numbered 448 (28.2%), while those found to be "informed" only about the manner of its execution or only about its purpose numbered 161 (10.2%) and 151 (9.5%), respectively. The remaining 826 (52.1%) patients had either no information, or the information they had was very poor or incorrect (this was particularly true if they had been consulting websites). Being "informed" was associated with level of education (high), type of referring physician (specialist) and with an appropriate referral diagnosis specified in the EMG request. The quality of patient information on EMG was found to be very poor and could be improved. Physicians referring patients for EMG examinations, especially general practitioners, should assume primary responsibility for patient education and counseling in this field.

  20. Quality of Life in Elderly Cancer Patients Undergoing Chemotherapy.

    Science.gov (United States)

    Lavdaniti, Maria; Zyga, Sofia; Vlachou, Eugenia; Sapountzi-Krepia, Despina

    2017-01-01

    As life expectancy increases, it is expected that 60% of all cases of cancer will be detected in elderly patients in the next two decades. Cancer treatment for older persons is complicated by a number of factors, thus negatively affecting patients' quality of life. The purpose of this study is to investigate quality of life in elderly cancer patients undergoing chemotherapy. This study was descriptive and non-experimental. It was conducted in one large hospital in a major city of Northern Greece. The sample was convenience comprising 53 elderly cancer patients undergoing cycle 3 chemotherapy. The data was collected using the Functional Assessment of Cancer Therapy scale and included questions related to demographic and clinical characteristics. The majority of participants were men (n = 27, 50.9%) who were married (n = 32, 79.5%). Their mean age was 70.07 ± 3.60. Almost half of the sample (n = 30, 56.6%) had colon cancer. There was a statistical significant difference between men and women pertaining to physical wellbeing (p = 0.004) and overall quality of life (p quality of life (p quality of life (p quality of life and its related factors in elderly cancer patients. It is highly recommended to envisage measures for improving quality of life in this group of cancer patients.

  1. Knowledge of electromyography (EMG) in patients undergoing EMG examinations

    Science.gov (United States)

    Mondelli, Mauro; Aretini, Alessandro; Greco, Giuseppe

    2014-01-01

    Summary The aim of this study was to evaluate knowledge of electromyography (EMG) in patients undergoing the procedure. In one year, 1,586 consecutive patients (mean age 56 years; 58.8% women) were admitted to two EMG labs to undergo EMG for the first time. The patients found to be “informed” about the how an EMG examination is performed and about the purpose of EMG numbered 448 (28.2%), while those found to be “informed” only about the manner of its execution or only about its purpose numbered 161 (10.2%) and 151 (9.5%), respectively. The remaining 826 (52.1%) patients had either no information, or the information they had was very poor or incorrect (this was particularly true if they had been consulting websites). Being “informed” was associated with level of education (high), type of referring physician (specialist) and with an appropriate referral diagnosis specified in the EMG request. The quality of patient information on EMG was found to be very poor and could be improved. Physicians referring patients for EMG examinations, especially general practitioners, should assume primary responsibility for patient education and counseling in this field. PMID:25473740

  2. Immediate hemodynamic response to furosemide in patients undergoing chronic hemodialysis.

    Science.gov (United States)

    Schmieder, R E; Messerli, F H; deCarvalho, J G; Husserl, F E

    1987-01-01

    To evaluate the effect of furosemide on cardiovascular hemodynamics in patients with end-stage renal failure, we studied ten patients undergoing hemodialysis three times a week. Arterial pressure, heart rate, and cardiac output (indocyanine green dye) were measured in triplicate; total peripheral resistance and central blood volume were calculated by standard formulas. Hemodynamics were determined at baseline and 5, 10, 15, and 30 minutes after intravenous (IV) bolus injection of furosemide 60 mg. Furosemide produced a decrease in central blood volume of -13% +/- 2.2% from pretreatment values (P less than .01) that was most pronounced five minutes after injection, together with a fall in cardiac output (from 6.76 +/- 0.59 to 6.17 +/- 0.52 L/min, P less than .10). Stroke volume decreased with a maximum fall occurring after 15 minutes (from 84 +/- 7 to 79 +/- 7 mL/min, P less than .05), and total peripheral resistance increased (from 15.8 +/- 2.1 to 17.8 +/- 2.3 units, P less than .05) after furosemide. Arterial pressure and heart rate did not change. The decrease in central blood volume reflects a shift of the total blood volume from the cardiopulmonary circulation to the periphery, suggesting dilation of the peripheral venous bed. Thus, even in patients undergoing hemodialysis, furosemide acutely decreases left ventricular preload by venous dilation and should therefore prove to be beneficial in acute volume overload.

  3. Massage for Children Undergoing Hematopoietic Cell Transplantation: A Qualitative Report

    Science.gov (United States)

    Ackerman, Sara L.; Lown, E. Anne; Dvorak, Christopher C.; Dunn, Elizabeth A.; Abrams, Donald I.; Horn, Biljana N.; Degelman, Marcia; Cowan, Morton J.; Mehling, Wolf E.

    2012-01-01

    Background. No in-depth qualitative research exists about the effects of therapeutic massage with children hospitalized to undergo hematopoietic cell transplantation (HCT). The objective of this study is to describe parent caregivers' experience of the effects of massage/acupressure for their children undergoing HCT. Methods. We conducted a qualitative analysis of open-ended interviews with 15 parents of children in the intervention arm of a massage/acupressure trial. Children received both practitioner and parent-provided massage/acupressure. Results. Parents reported that their child experienced relief from pain and nausea, relaxation, and greater ease falling asleep. They also reported increased caregiver competence and closeness with their child as a result of learning and performing massage/acupressure. Parents supported a semistandardized massage protocol. Conclusion. Massage/acupressure may support symptom relief and promote relaxation and sleep among pediatric HCT patients if administered with attention to individual patients' needs and hospital routines and may relieve stress among parents, improve caregiver competence, and enhance the sense of connection between parent and child. PMID:22474526

  4. [Has ketamine preemptive analgesic effect in patients undergoing abdominal hysterectomy?].

    Science.gov (United States)

    Karaman, Semra; Kocabaş, Seden; Zincircioğlu, Ciler; Firat, Vicdan

    2006-07-01

    The aim of this study was to determine if preemptive use of the NMDA receptor antogonist ketamine decreases postoperative pain in patients undergoing abdominal hystrectomy. A total of 60 patients admitted for total abdominal hysterectomy were included in this study after the approval of the ethic committee, and the patients were randomly classified into three groups. After standart general anaesthesia, before or after incision patients received bolus saline or ketamine. Group S received only saline while Group Kpre received ketamine 0.4 mg/kg before incision and saline after incision, and Group Kpost received saline before incision and 0.4 mg/kg ketamine after incision. Postoperatif analgesia was maintained with i.v. PCA morphine. Pain scores were assessed with Vizüal Analog Scale (VAS), Verbal Rating Scale (VRS) at 1., 2, 3., 4., 8., 12. ve 24. hours postoperatively. First analgesic requirement time, morphine consumption and side effects were recorded. There were no significant differences between groups with respect to VAS / VRS scores, the time for first analgesic dose, and morphine consumption ( p>0.05). Patients in Group S had significantly lower sedation scores than either of the ketamine treated groups ( pketamin had no preemptive analgesic effect in patients undergoing abdominal hysterectomy, but further investigation is needed for different operation types and dose regimens.

  5. Children Undergoing Radiotherapy: Swedish Parents’ Experiences and Suggestions for Improvement

    Science.gov (United States)

    Mullaney, Tara; Nilsson, Kristina; Wickart-Johansson, Gun; Svärd, Anna-Maja; Nyholm, Tufve; Lindh, Jack; Lindh, Viveca

    2015-01-01

    Approximately 300 children, from 0 to 18 years old, are diagnosed with cancer in Sweden every year. Of these children, 80–90 of them undergo radiotherapy treatment for their cancer. Although radiotherapy is an encounter with advanced technology, few studies have investigated the child’s and the parent’s view of the procedure. As part of an ongoing multicenter study aimed to improve patient preparation and the care environment in pediatric radiotherapy, this article reports the findings from interviews with parents at baseline. The aim of the present study was twofold: to describe parents’ experience when their child undergoes radiotherapy treatment, and to report parents’ suggestions for improvements during radiotherapy for their children. Sixteen mothers and sixteen fathers of children between 2–16 years old with various cancer diagnoses were interviewed. Data were analyzed using content analysis. The findings showed that cancer and treatment turns people’s lives upside down, affecting the entire family. Further, the parents experience the child’s suffering and must cope with intense feelings. Radiotherapy treatment includes preparation by skilled and empathetic staff. The parents gradually find that they can deal with the process; and lastly, parents have suggestions for improvements during the radiotherapy treatment. An overarching theme emerged: that despair gradually turns to a sense of security, with a sustained focus on and close interaction with the child. In conclusion, an extreme burden was experienced around the start of radiotherapy, though parents gradually coped with the process. PMID:26509449

  6. Maintaining periodontal health in patients undergoing orthodontic treatment

    Directory of Open Access Journals (Sweden)

    Shobhana Misra

    2012-01-01

    Full Text Available Presence of fixed orthodontic appliances in the mouth leads to accumulation of food debris and an elevation in the amount of plaque. It also hinders plaque removal by tooth brushing alone. Chemical agents may be used during the active phase of orthodontic treatment to reduce the bacterial plaque accumulation and decrease the occurrence of periodontal disease in these patients. The present study was therefore done to compare the efficacy of chemical plaque control by chlorhexidiene in patients undergoing orthodontic treatment. Forty five subjects for this double blind study were assigned randomly into three groups of 15 each. Gingival inflammation, plaque accumulation, and bleeding on probing, were recorded at baseline (10 days after prophylaxis, and at the end of one month in all the three groups. The data obtained was subjected to stastical analysis. Anova test showed significant difference among all the three groups for bleeding index, modified gingival index and plaque index. Paired t test showed significant differences in bleeding index for pre and post treatment recordings for chlorhexidine group. Modified gingival index showed significant difference in the chlorhexidine group. For plaque index significant difference was found for chlorhexidine, and control groups. Chlorhexidine mouthrinse 0.12% was found to be the most effective in reducing the bleeding scores, modified gingival index scores and the plaque index scores. It can therefore be said that chlorhexidine mouthrinse 0.12% provides greater benefits to the patients undergoing fixed orthodontic treatment.

  7. [Eradication of Staphylococcus aureus in carrier patients undergoing joint arthroplasty].

    Science.gov (United States)

    Barbero Allende, José M; Romanyk Cabrera, Juan; Montero Ruiz, Eduardo; Vallés Purroy, Alfonso; Melgar Molero, Virginia; Agudo López, Rosa; Gete García, Luis; López Álvarez, Joaquín

    2015-02-01

    Prosthetic joint infection (PJI) is a complication with serious repercussions and its main cause is Staphylococcus aureus. The purpose of this study is to determine whether decolonization of S.aureus carriers helps to reduce the incidence of PJI by S.aureus. An S.aureus screening test was performed on nasal carriers in patients undergoing knee or hip arthroplasty between January and December 2011. Patients with a positive test were treated with intranasal mupirocin and chlorhexidine soap 5 days. The incidence of PJI was compared with patients undergoing the same surgery between January and December 2010. A total of 393 joint replacements were performed in 391 patients from the control group, with 416 joint replacements being performed in the intervention group. Colonization study was performed in 382 patients (91.8%), of which 102 were positive (26.7%) and treated. There was 2 PJI due S.aureus compared with 9 in the control group (0.5% vs 2.3%, odds ratio [OR]: 0.2, 95% confidence interval [CI]: 0.4 to 2.3, P=.04). In our study, the detection of colonization and eradication of S.aureus carriers achieved a significant decrease in PJI due to S.aureus compared to a historical group. Copyright © 2013 Elsevier España, S.L.U. y Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

  8. Supporting and Empowering Nurses Undergoing Critical Care Certification.

    Science.gov (United States)

    Beaudoin, Geneviève; St-Louis, Lyne; Alderson, Marie

    2016-01-01

    Nurses working in critical care settings face multiple sources of stress, such as complex clinical situations and the use of new advanced technologies, which can affect their psychological health. Literature suggests that the promotion of educational activities, such as a certification process within a specialty, can contribute to nurses' empowerment, professional growth, and personal satisfaction. However, it is of utmost importance that the institutional organizations support nurses undergoing the certification process to optimize positive impacts of this educational activity on the nurses, on the patients, and within the institutions. In the course of a graduate studies stage, an educational program aiming at supporting and creating an empowering environment for nurses undergoing a critical care certification process was developed and implemented, in a Canadian intensive care unit, over a 7-month period. The Humanist model was used as a theoretical framework and was complemented by the problem-based learning pedagogical approach. A postintervention qualitative questionnaire revealed that the program was tailored to nurses' learning needs and that participants felt supported by their institution throughout the process. This program could help institutions support nurses in achieving higher professional and personal development levels through specialty certification.

  9. Dental Health of Patients Undergoing Hemodialysis (A Study

    Directory of Open Access Journals (Sweden)

    Vinay Mohan

    2011-01-01

    Full Text Available The primary purpose of this study was to determine the oral manifestations of patients undergoing dialysis. Two subgroups of the population were studied: (1 Those who have been on dialysis for less than one year, (2 those who have been on dialysis for more than one year. Two dental indices–periodontal index and decayed, missing, filled index were used to identify periodontal status, dental canes activity. Data were compiled and analyzed by using the unpaired t-test. Results suggested that 100% (n = 26 of the patients undergoing dialysis presented with some form of periodontal disease (mean value = 2.24, standard deviation = 1.33. Majority of the patients displayed either established periodontal disease (57.6% or the beginning of periodontal disease (38 4%. Approximately, 70% of the patients had high decayed, missing, filled index (mean value = 6.19, standard deviation = 6.40. Findings led to the conclusion that patients on dialysis need comprehensive professional oral care and self-care instructions. The source of infection in oral cavity can cause variety of systemic diseases, causing morbidity and mortality in these immune-suppressed patients.

  10. Predictors of anxiety and resilience in adolescents undergoing cancer treatment.

    Science.gov (United States)

    Wu, Li-Min; Sheen, Jiunn-Ming; Shu, Hsiu-Lan; Chang, Shu-Chen; Hsiao, Chih-Cheng

    2013-01-01

    To report a study examining the relationships among coping, anxiety and resilience and to identify predictors of anxiety and resilience in adolescents undergoing cancer treatment. Anxiety is the main psychological disturbance in adolescents with cancer, but predictors in the context of anxiety related cancer treatments have not been investigated. Cross-sectional study. Adolescents (n = 131) recruited from three medical centres between 2010-2011. The eligible participants were diagnosed with cancer, without mental disease and receiving chemotherapy. Participants were assessed with the paediatric cancer coping scale, revised children's manifest anxiety scale, second edition, and the Haase adolescent resilience in illness scale. Over 20% of participants scored high on worry. The most commonly used coping strategy was cognitive coping, followed by problem-oriented coping and finally by defensive coping. There was a statistically significant correlation between defensive coping and level of worry. Resilience was positively correlated with cognitive coping and problem-oriented coping. The cognitive coping and defensive coping were found to predict anxiety and resilience significantly by a step-wise multiple regression analysis and accounted for 40·9% and 46·5% of total variance, respectively. Cognitive coping and defensive coping are predictors for the level of anxiety and resilience in adolescents undergoing cancer treatment. Health providers should evaluate coping behaviour in patients and work towards a cognitive and problem-oriented coping style that will benefit the patient's mental health during treatment. © 2012 Blackwell Publishing Ltd.

  11. Simultaneous and Continuous Estimation of Shoulder and Elbow Kinematics from Surface EMG Signals

    Science.gov (United States)

    Zhang, Qin; Liu, Runfeng; Chen, Wenbin; Xiong, Caihua

    2017-01-01

    In this paper, we present a simultaneous and continuous kinematics estimation method for multiple DoFs across shoulder and elbow joint. Although simultaneous and continuous kinematics estimation from surface electromyography (EMG) is a feasible way to achieve natural and intuitive human-machine interaction, few works investigated multi-DoF estimation across the significant joints of upper limb, shoulder and elbow joints. This paper evaluates the feasibility to estimate 4-DoF kinematics at shoulder and elbow during coordinated arm movements. Considering the potential applications of this method in exoskeleton, prosthetics and other arm rehabilitation techniques, the estimation performance is presented with different muscle activity decomposition and learning strategies. Principle component analysis (PCA) and independent component analysis (ICA) are respectively employed for EMG mode decomposition with artificial neural network (ANN) for learning the electromechanical association. Four joint angles across shoulder and elbow are simultaneously and continuously estimated from EMG in four coordinated arm movements. By using ICA (PCA) and single ANN, the average estimation accuracy 91.12% (90.23%) is obtained in 70-s intra-cross validation and 87.00% (86.30%) is obtained in 2-min inter-cross validation. This result suggests it is feasible and effective to use ICA (PCA) with single ANN for multi-joint kinematics estimation in variant application conditions. PMID:28611573

  12. Simultaneous and Continuous Estimation of Shoulder and Elbow Kinematics from Surface EMG Signals

    Directory of Open Access Journals (Sweden)

    Qin Zhang

    2017-05-01

    Full Text Available In this paper, we present a simultaneous and continuous kinematics estimation method for multiple DoFs across shoulder and elbow joint. Although simultaneous and continuous kinematics estimation from surface electromyography (EMG is a feasible way to achieve natural and intuitive human-machine interaction, few works investigated multi-DoF estimation across the significant joints of upper limb, shoulder and elbow joints. This paper evaluates the feasibility to estimate 4-DoF kinematics at shoulder and elbow during coordinated arm movements. Considering the potential applications of this method in exoskeleton, prosthetics and other arm rehabilitation techniques, the estimation performance is presented with different muscle activity decomposition and learning strategies. Principle component analysis (PCA and independent component analysis (ICA are respectively employed for EMG mode decomposition with artificial neural network (ANN for learning the electromechanical association. Four joint angles across shoulder and elbow are simultaneously and continuously estimated from EMG in four coordinated arm movements. By using ICA (PCA and single ANN, the average estimation accuracy 91.12% (90.23% is obtained in 70-s intra-cross validation and 87.00% (86.30% is obtained in 2-min inter-cross validation. This result suggests it is feasible and effective to use ICA (PCA with single ANN for multi-joint kinematics estimation in variant application conditions.

  13. Robust receding horizon control for networked and distributed nonlinear systems

    CERN Document Server

    Li, Huiping

    2017-01-01

    This book offers a comprehensive, easy-to-understand overview of receding-horizon control for nonlinear networks. It presents novel general strategies that can simultaneously handle general nonlinear dynamics, system constraints, and disturbances arising in networked and large-scale systems and which can be widely applied. These receding-horizon-control-based strategies can achieve sub-optimal control performance while ensuring closed-loop stability: a feature attractive to engineers. The authors address the problems of networked and distributed control step-by-step, gradually increasing the level of challenge presented. The book first introduces the state-feedback control problems of nonlinear networked systems and then studies output feedback control problems. For large-scale nonlinear systems, disturbance is considered first, then communication delay separately, and lastly the simultaneous combination of delays and disturbances. Each chapter of this easy-to-follow book not only proposes and analyzes novel ...

  14. Building capability through networking with investors and researchers

    DEFF Research Database (Denmark)

    Wang, Daojuan; Schøtt, Thomas

    A startup requires financing, typically, and the startup is based on innovation, often. Capabilities for innovation and financing may be built simultaneously and created jointly at inception. Co-creation of capabilities for financing and innovation is accounted for in this study. Co...... of startups at inception, by 9,161 entrepreneurs, surveyed in Global Entrepreneurship Monitor in 49 countries. Co-creation is found to be reduced by the entrepreneur’s networking in the private sphere of family and friends, but to be benefiting from networking in the public sphere, especially by networking...... with investors and researchers simultaneously. The findings contribute to understanding capability building as embedded in networks around the startup....

  15. A desirability functions-based approach for simultaneous ...

    African Journals Online (AJOL)

    simultaneous optimization of quantitative and ordinal response variables. But none of these approaches results in an efficient optimal solution with respect to the desirability values of all the individual response variables. It motivated us to develop a more useful approach for simultaneously optimizing industrial processes ...

  16. Components of simultaneous interpreting: Comparing interpreting with shadowing and paraphrasing.

    NARCIS (Netherlands)

    Christoffels, I.K.; de Groot, A.M.B.

    2004-01-01

    Simultaneous interpreting is a complex task where the interpreter is routinely involved in comprehending, translating and producing language at the same time. This study assessed two components that are likely to be major sources of complexity in SI: The simultaneity of comprehension and production,

  17. Simultaneous Bilateral Bell's palsy in a Nigerian man | Owolabi ...

    African Journals Online (AJOL)

    Bilateral Bellfs palsy occurring simultaneously is exceedingly rare. We report a case of a 27.year.old Nigerian man with bilateral Bellfs palsy, that occurred simultaneously, who had remarkable response to steroid and physiotherapy. We emphasized the importance of considering Bellfs palsy and the various differential ...

  18. Simultaneous Determination of Co-formulated Matrine and ...

    African Journals Online (AJOL)

    HP

    simultaneously [14-19]. The literature was mainly focused on determination of the content of matrine and secnidazole one by one. The aim of this study is to develop and validate a simple, rapid, senstive and reproducible HPLC method to determine matrine and secnidazole simultaneously when combined in a suppository.

  19. Simultaneous growth and yield models for Eucalyptus grandis (Hill ...

    African Journals Online (AJOL)

    Simultaneous stand-level growth and yield models for Eucalyptus grandis in Zimbabwe were developed from Correlated Curve Trend (CCT) and Nelder wheel experiments replicated on five different sites. Nonlinear three-stage least squares method was used to simultaneously fit prediction and projection equations for ...

  20. Part 6: Modelling of simultaneous chemical-biological P removal ...

    African Journals Online (AJOL)

    drinie

    The use of simultaneous chemical precipitation in modified activated sludge systems exhibiting biological excess phosphate removal. Part 6: Modelling of simultaneous chemical-biological. P removal – Review of existing models. DW de Haas#, MC Wentzel* and GA Ekama. Dept. of Civil Engineering, University of Cape ...