WorldWideScience

Sample records for networking services acns

  1. Acne

    Science.gov (United States)

    Acne is a common skin disease that causes pimples. Pimples form when hair follicles under your skin ... neck, back, chest, and shoulders. Anyone can get acne, but it is common in teenagers and young ...

  2. Acne

    Directory of Open Access Journals (Sweden)

    Emel Güngör

    2012-12-01

    Full Text Available Acne is a chronic disorder of pilosebaceous unit clinically characterized by comedones, papules, pustules, nodules and scarring. It affects almost 85% of young people between 12-24 years of age. Four main pathophysiologic factors that influence the development of acne are; increased sebum secretion, abnormal follicular desquamation, P. acnes colonization of the follicle and inflammation. The treatment of acne includes; topical retinoids, topical antimicrobial agents, systemic antibiotics, hormonal therapy and oral isotretinoin. Topical retinoids should be used as the first choice in comedonal acne, in combination with topical and/or systemic antimicrobials for mild to moderate inflammatory acne and as maintenance therapy once clearance has been achieved. Topical and systemic antibiotics which are used to treat moderate inflammatory acne should not be used as monotherapy but combined with topical benzoyl peroxide or topical retinoids and should be stopped as soon as possible. Hormonal therapy is an excellent choice for women, especially if oral contraception is desired. It may also be used for female patients with severe seborrhea, late onset acne and with proven hyperandrogenism. Oral isotretinoin targets all pathophysiologic factors in acne and is the mainstay of therapy for severe acne. It has to be kept in mind that the management of acne and compliance of the patient to the treatment can be enhanced by a number of general strategies such as education about acne and treatment, skin care, diet and adjuvant procedures.

  3. Acne

    Science.gov (United States)

    ... may be prescribed: Retinoic acid cream or gel (tretinoin, Retin-A) Prescription formulas of benzoyl peroxide, sulfur, resorcinol, or salicylic acid Topical azelaic acid For women whose acne is caused or made worse by hormones: A ...

  4. Acne

    Science.gov (United States)

    ... Certain things can trigger or make acne worse:Hormonal changes. This happens during puberty, before a woman’s period (menstrual cycle), or during pregnancy.Certain medicines. This includes supplements or steroids that ...

  5. Baby Acne

    Science.gov (United States)

    ... Sections Symptoms & causes Diagnosis & treatment Print Overview Baby acne Baby acne Baby acne is usually characterized by small red ... March 30, 2015. Related Baby rashes Milia Baby acne Symptoms & causes Diagnosis & treatment Advertisement Mayo Clinic does ...

  6. Propionibacterium acnes

    Science.gov (United States)

    Goto, Hiroshi; Usui, Yoshihiko; Umazume, Akihiko; Uchida, Keisuke; Eishi, Yoshinobu

    2017-11-01

    To detect Propionibacterium acnes from intraocular granuloma in patients with ocular sarcoidosis. Ten patients (10 eyes) with uveitis associated with sarcoidosis, who underwent vitrectomy to remove the epiretinal membrane were analysed. The patients were 70.4±7.6 (mean±SD) years of age, and the observation period from diagnosis of sarcoidosis until vitrectomy was 27.6±15.1 months. Histopathological examination of paraffin-embedded sections of the excised epiretinal membranes was conducted by H&E staining and immunohistochemical staining using PAB antibody, which is a monoclonal antibody against P. acnes . Four patients with idiopathic epiretinal membrane and four patients with epiretinal membrane caused by chronic uveitis other than sarcoidosis were included as control. Granuloma in the epiretinal membrane was observed in 4 of 10 patients with sarcoidosis, and all the granulomas were positive for PAB. In one patient without granuloma in the epiretinal membrane, PAB immunoreactivity was found in inflammatory cells, presumably macrophages. No granuloma and no PAB immunoreactivity were detected in all control patients, except one with chronic uveitis in whom faint PAB immunoreactivity was detected in inflammatory cells. P. acnes was detected from granulomas formed in the epiretinal membrane of patients with sarcoidosis. The significance of P. acnes in the pathogenesis of uveitis associated with sarcoidosis remains to be determined. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

  7. Generic Network Location Service

    Directory of Open Access Journals (Sweden)

    Laban Mwansa

    2010-11-01

    Full Text Available This work presents the Generic Network Location Service based on the Chord implementation utilizing data structures called distributed hash tables (DHT or structured overlay networks, which are used to build scalable self-managing distributed systems. The provided algorithms guarantee resilience in the presence of dynamism: they guarantee consistent lookup results in the presence of nodes failing and leaving. Generic Network Location Service provides a Location Service system based on DHT technology, which is storing device location records in nodes within a Chord DHT. Location records are consisting of network device identification keys as attributes, which are used to create replicas of additional location records through established Chord hashing mechanisms. Storing device location records, in places address-able (using the DHT lookup by individual location record keys provides a simple way of implementing transla¬tion functions similar to well¬ known network services (e.g. ARP, DNS, ENUM. The generic network location ser¬vice presented in the paper is not supposed to be a substitu¬tion of the existing translation techniques (e.g. ARP, DNS, ENUM, but it is considered as an overlay service that uses data available in existing systems and provides some translations currently unavailable.

  8. Acne vulgar Acne vulgar

    Directory of Open Access Journals (Sweden)

    Lorivaldo Minelli

    1978-11-01

    Full Text Available In this paper the author presents a study on vulgar or juvenile acne with general considerations about the disease and analyzes the main ethiopathogenie and clinical aspects of it. Finally he considers its treatment. No presente trabalho, apresenta-se um estudo da acne vulgar ou juvenil, tecendo-se considerações gerais sobre essa doença e analisando-se os principais aspectos etiopatogênicos e clínicos da mesma. Aborda-se, finalmente, de modo sucinto, aspectos terapêuticos da moléstia.

  9. Cable networks, services, and management

    CERN Document Server

    2015-01-01

    Cable Networks, Services, and Management is the first book to cover cable networks, services, and their management, in-depth, for network operators, engineers, researchers, and students. Thirteen experts in various fields have contributed their knowledge of network architectures and services, Operations, Administration, Maintenance, Provisioning, Troubleshooting (OAMPT) for residential and business services, cloud, Software Defined Networks (SDN), as well as virtualization concepts and their applications as part of the future directions of cable networks. The book begins by introducing architecture and services for Data Over Cable Service Interface Specification (DOCSIS) 3.0/ 3.1, Converged Cable Access Platform (CCAP), Content Distribution Networks (CDN, IP TV, and Packet Cable and Wi-Fi for Residential Services. Topics that are discussed in proceeding chapters include: operational systems and management architectures, service orders, provisioning, fault manageme t, performance management, billing systems a...

  10. Heterogenous networks and services

    DEFF Research Database (Denmark)

    Tan, Su-En

    2006-01-01

    of the market. If mainstream technology firms do not address the disruption, it is likely they will fail and the new disruptive firm will grow in size and importance in the industry. As we move to 3G (3rd Generation Mobile Services) and beyond 3G, one of the biggest challenges is to bridge network heterogeneity...... representations of strategy, will then help to determine the success or failure of the technology. This is shown typically in the case of WiFi. WiFi is a wireless technology that addressed a new market, but was soon adopted as a complement by mobile operators into their suite of services. However, the future......This thesis considers the development of the mobile industry from a techno-economic perspective. Theory of disruptive technologies and related theories are examined and further developed. While much of technology change has been analysed on either a technical level or a market level, another plane...

  11. [Acne vulgaris].

    Science.gov (United States)

    Zouboulis, C C

    2014-08-01

    Acne vulgaris is worldwide the most common skin disease. Acne is an inflammatory disorder in whose emergence androgens, PPAR ligands, the IGF-1 signaling pathway, regulating neuropeptides and environmental factors are probably involved. These factors interrupt the natural cycling process in the sebaceous gland follicle and support the transition of microcomedones to comedones and inflammatory lesions. Proinflammatory lipids and cytokines are mediators for the development of acne lesions. Bacterial antigens can potentate the inflammatory phenomena. Acne is predominantly treated with combination therapy. Selecting a treatment regimen depends on the exact classification of acne type and severity. The development of scars is the main criterion for the choice of systemic therapy. Retinoids for mild comedonal acne and the combination of retinoids with antibiotics and/or benzoyl peroxide for mild to moderate papulopustular acne are the drugs of first choice for topical treatment. The use of topical antibiotics is not recommended any more because of the development of resistant bacterial strains. Systemic antibiotics, in combination with topical retinoids and/or benzoyl peroxide, for moderate papular/nodular acne and isotretinoin for severe nodular/conglobate acne are the columns of systemic acne treatment. Systemic anti-androgens are used in women against moderate papulopustular acne. Due to advances in the understanding of the underlying inflammatory mechanisms in recent years the development of new therapeutic agents with good efficacy and better side effect profile should be expected in the future.

  12. Cloud services, networking, and management

    CERN Document Server

    da Fonseca, Nelson L S

    2015-01-01

    Cloud Services, Networking and Management provides a comprehensive overview of the cloud infrastructure and services, as well as their underlying management mechanisms, including data center virtualization and networking, cloud security and reliability, big data analytics, scientific and commercial applications. Special features of the book include: State-of-the-art content. Self-contained chapters for readers with specific interests. Includes commercial applications on Cloud (video services and games).

  13. Service entity network virtualization architecture and model

    Science.gov (United States)

    Jin, Xue-Guang; Shou, Guo-Chu; Hu, Yi-Hong; Guo, Zhi-Gang

    2017-07-01

    Communication network can be treated as a complex network carrying a variety of services and service can be treated as a network composed of functional entities. There are growing interests in multiplex service entities where individual entity and link can be used for different services simultaneously. Entities and their relationships constitute a service entity network. In this paper, we introduced a service entity network virtualization architecture including service entity network hierarchical model, service entity network model, service implementation and deployment of service entity networks. Service entity network oriented multiplex planning model were also studied and many of these multiplex models were characterized by a significant multiplex of the links or entities in different service entity network. Service entity networks were mapped onto shared physical resources by dynamic resource allocation controller. The efficiency of the proposed architecture was illustrated in a simulation environment that allows for comparative performance evaluation. The results show that, compared to traditional networking architecture, this architecture has a better performance.

  14. Liner Service Network Design

    DEFF Research Database (Denmark)

    Brouer, Berit Dangaard

    This thesis concerns design of liner shipping networks using operations research to optimize liner shipping networks at the strategic, tactical and operational level. Liner shipping networks are often compared to public transit networks as they consist of a set of scheduled sailings connecting....... The research field of liner shipping network design is relatively young and many open research questions exists. Among others, a unified and rich mathematical model formulating the main characteristics of the business domain has not been clearly described and exact methods for such mathematical models...... are still not able to solve significant instances of this complex optimization problem. In this thesis two research directions are explored within the field: The first research direction contributes to basic research on the liner shipping network design problem by describing the domain seen from...

  15. Production, Innovation and Service Networks

    DEFF Research Database (Denmark)

    Slepniov, Dmitrij; Wæhrens, Brian Vejrum; Johansen, John

    2012-01-01

    Production, innovation and service networks of companies all over the world become increasingly decentralised, specialised and interdependent. These three characteristics combined inevitably lead to the formation of complex configurations of resources, crossing both national and organisational...... borders. The existing studies do not adequately address the complex interplay between co-evolving production, innovation and service networks. The widening geographical and cognitive gaps between these networks mean that coordinating them and managing their interfaces in a global operations context...... are becoming strategically important. The purpose of this paper is to address this issue and to develop a number of propositions about the development and organisation of these networks. The paper highlights the critical importance of engineering operations in this process. The propositions are developed...

  16. Production, Innovation and Service Networks

    DEFF Research Database (Denmark)

    Slepniov, Dmitrij; Wæhrens, Brian Vejrum; Johansen, John

    2011-01-01

    Production, innovation and service networks of companies all over the world become increasingly decentralized, specialized and interdependent. The three characteristics combined inevitably lead to the formation of complex configurations of assets and capabilities crossing both national and organi......Production, innovation and service networks of companies all over the world become increasingly decentralized, specialized and interdependent. The three characteristics combined inevitably lead to the formation of complex configurations of assets and capabilities crossing both national...... and organisational borders. The existing studies do not adequately address the complex interplay between co-evolving production, innovation and service networks. The widening geographical and cognitive gap between these networks means that coordinating them and managing their interfaces in global operations context...... is becoming strategically important. The purpose of this paper is to address this issue and to develop a number of propositions about how companies can organize these networks and coordinate between them effectively. The propositions are developed by employing the design science approach based on a literature...

  17. Acne Vulgaris

    Directory of Open Access Journals (Sweden)

    Ashok Ghorpade

    1982-01-01

    Full Text Available Acne vulgaris causes much emotional trauma, social embarrassment and cosmetic disfiguration in teenage girls and boys. The multifactorial etiology, pathogenesis and clinical features of this condition are narrated. The mechanism of comedo formation is briefly discussed. Recent concepts in the management of this chronic malady are critically reviewed.

  18. Acne vulgaris.

    Science.gov (United States)

    Purdy, Sarah; de Berker, David

    2011-01-05

    Acne vulgaris affects over 80% of teenagers, and persists beyond the age of 25 years in 3% of men and 12% of women. Typical lesions of acne include comedones, inflammatory papules, and pustules. Nodules and cysts occur in more severe acne and can cause scarring and psychological distress. We conducted a systematic review and aimed to answer the following clinical question: What are the effects of topical and oral treatments in people with acne vulgaris? We searched: Medline, Embase, The Cochrane Library, and other important databases up to February 2010 (Clinical Evidence reviews are updated periodically; please check our website for the most up-to-date version of this review). We included harms alerts from relevant organisations such as the US Food and Drug Administration (FDA) and the UK Medicines and Healthcare products Regulatory Agency (MHRA). We found 69 systematic reviews, RCTs, or observational studies that met our inclusion criteria. We performed a GRADE evaluation of the quality of evidence for interventions. In this systematic review we present information relating to the effectiveness and safety of the following interventions: topical treatments (adapalene, azelaic acid, benzoyl peroxide, clindamycin, erythromycin [alone or plus zinc]; isotretinoin, tetracycline, tretinoin); and oral treatments (doxycycline, isotretinoin, lymecycline, minocycline, oxytetracycline, tetracycline).

  19. Acne Scars

    Science.gov (United States)

    ... different skin problem. Image used with permission of Journal of the American Academy of Dermatology. J Am Acad Dermatol 2001;45:116 . References: ... Images of acne scars used with permission of Journal of the American Academy of Dermatology . J Am Acad Dermatol 2001;45:109-17 ...

  20. Service Differentiation in Residential Broadband Networks

    DEFF Research Database (Denmark)

    Sigurdsson, Halldór Matthias

    2004-01-01

    As broadband gains widespread adoption with residential users, revenue generating voice- and video-services have not yet taken off. This slow uptake is often attributed to lack of Quality of Service management in residential broadband networks. To resolve this and induce service variety, network...... access providers are implementing service differentiation in their networks where voice and video gets prioritised before data. This paper discusses the role of network access providers in multipurpose packet based networks and the available migration strategies for supporting multimedia services...... in digital subscriber line (DSL) based residential broadband networks. Four possible implementation scenarios and their technical characteristics and effects are described. To conclude, the paper discusses how network access providers can be induced to open their networks for third party service providers....

  1. Consolidated Afloat Networks and Enterprise Services (CANES)

    Science.gov (United States)

    2016-03-01

    2016 Major Automated Information System Annual Report Consolidated Afloat Networks and Enterprise Services (CANES) Defense Acquisition Management...DSN Phone: 524-7909 DSN Fax: 524-7950 Date Assigned: November 15, 2013 Program Information Program Name Consolidated Afloat Networks and...4 Program Description Consolidated Afloat Networks & Enterprise Services (CANES) is the Navy’s only Program of Record to replace existing afloat

  2. Location-Based Services in Vehicular Networks

    Science.gov (United States)

    Wu, Di

    2013-01-01

    Location-based services have been identified as a promising communication paradigm in highly mobile and dynamic vehicular networks. However, existing mobile ad hoc networking cannot be directly applied to vehicular networking due to differences in traffic conditions, mobility models and network topologies. On the other hand, hybrid architectures…

  3. 78 FR 14359 - Verizon Business Networks Services, Inc., Specialist-Tech Customer Service, Philadelphia, PA...

    Science.gov (United States)

    2013-03-05

    ... Employment and Training Administration Verizon Business Networks Services, Inc., Specialist-Tech Customer Service, Philadelphia, PA; Verizon Business Networks Services, Inc., Specialist-Tech Customer Service...-Tech Customer Service, Philadelphia, Pennsylvania and Verizon Business Networks Services, Inc...

  4. Troubleshooting Assistance Services in Community Wireless Networks

    Directory of Open Access Journals (Sweden)

    P. Kriz

    2012-01-01

    Full Text Available We have identified new services intended for users and administrators of community wireless networks. Troubleshooting assistance services will assist the users during solution of communication problems, gathering data for expert analysis, informing the user about the state of the network (including outages, and so forth. Network administrators will be provided with a unique tool supporting the network analysis, operation, and development. We have mainly focused on the use cases and prerequirements—the problem of topology discovery.

  5. Topical Acne Treatments and Pregnancy

    Science.gov (United States)

    ... your health care provider. What are topical acne treatments? Topical acne treatments are medications applied directly on the skin that are used in the treatment of acne and other skin problems. Topical acne treatments can ...

  6. Performance modeling of network data services

    Energy Technology Data Exchange (ETDEWEB)

    Haynes, R.A.; Pierson, L.G.

    1997-01-01

    Networks at major computational organizations are becoming increasingly complex. The introduction of large massively parallel computers and supercomputers with gigabyte memories are requiring greater and greater bandwidth for network data transfers to widely dispersed clients. For networks to provide adequate data transfer services to high performance computers and remote users connected to them, the networking components must be optimized from a combination of internal and external performance criteria. This paper describes research done at Sandia National Laboratories to model network data services and to visualize the flow of data from source to sink when using the data services.

  7. Dark chocolate exacerbates acne.

    Science.gov (United States)

    Vongraviopap, Saivaree; Asawanonda, Pravit

    2016-05-01

    The effects of chocolate on acne exacerbations have recently been reevaluated. For so many years, it was thought that it had no role in worsening acne. To investigate whether 99% dark chocolate, when consumed in regular daily amounts, would cause acne to worsen in acne-prone male subjects, twenty-five acne prone male subjects were asked to consume 25 g of 99% dark chocolate daily for 4 weeks. Assessments which included Leeds revised acne scores as well as lesion counts took place weekly. Food frequency questionnaire was used, and daily activities were recorded. Statistically significant changes of acne scores and numbers of comedones and inflammatory papules were detected as early as 2 weeks into the study. At 4 weeks, the changes remained statistically significant compared to baseline. Dark chocolate when consumed in normal amounts for 4 weeks can exacerbate acne in male subjects with acne-prone skin. © 2015 The International Society of Dermatology.

  8. Service discovery in heterogeneous wireless networks

    NARCIS (Netherlands)

    Blangé, M.J.; Karkowski, I.P.; Vermeulen, B.C.B.

    2005-01-01

    In this paper we describe a possible solution to the problem of service discovery in heterogeneous wireless networks. This solution involves introduction of a network independent service discovery layer, with as main goal the improved robustness of applications running on top of it. A possible

  9. Acne and systemic disease.

    Science.gov (United States)

    Lolis, Margarita S; Bowe, Whitney P; Shalita, Alan R

    2009-11-01

    Acne is the most common disease of the skin. It affects 85% of teenagers, 42.5% of men, and 50.9% of women between the ages of 20 and 30 years.96,97 The role of hormones, particularly as a trigger of sebum production and sebaceous growth and differentiation, is well known. Excess production of hormones, specifically androgens, GH, IGF-1, insulin, CRH, and glucocorticoids, is associated with increased rates of acne development. Acne may be a feature in many endocrine disorders, including polycystic ovary disease, Cushing syndrome, CAH, androgen-secreting tumors, and acromegaly. Other nonendocrine diseases associated with acne include Apert syndrome, SAPHO syndrome, Behçet syndrome and PAPA syndrome. Acne medicamentosa is the development of acne vulgaris or an acneiform eruption with the use of certain medications. These medications include testosterone, progesterone,steroids, lithium, phenytoin, isoniazid, vitamins B2, B6, and B12, halogens, and epidermal growth factor inhibitors. Management of acne medicamentosa includes standard acne therapy. Discontinuation of the offending drug may be necessary in recalcitrant cases. Basic therapeutic interventions for acne include topical therapy, systemic antibiotics,hormonal agents, isotretinoin, and physical treatments. Generally, the severity of acne lesions determines the type of acne regimen necessary. The emergence of drug-resistant P acnes and adverse side effects are current limitations to effective acne management.

  10. Secure Service Discovery in Home Networks

    NARCIS (Netherlands)

    Scholten, Johan; van Dijk, H.W.; De Cock, Danny; Preneel, Bart; Kung, Antonio; d'Hooge, Michel

    2006-01-01

    This paper presents an architecture for secure service discovery for use in home networks. We give an overview and rationale of a cluster-based home network architecture that bridges different, often vendor specific, network technologies. We show how it integrates security, communication, and

  11. Planning contract and networks of home services

    Directory of Open Access Journals (Sweden)

    José Eudoro Narváez Viteri

    2010-06-01

    Full Text Available This article highlights the worrying increase in public investment in infrastructure works due to deficiencies at the stage of study and design, particularly in public utility services networks. Some cities lack real technical drawings and updated underground networks, especially in the former. Hence, no reliable information is difficult to require contractors, consultants about study designs appropriate public service networks in evident contradiction with the principle of contractual planning.

  12. Propionibacterium acnes in the pathogenesis and immunotherapy of acne vulgaris.

    Science.gov (United States)

    Liu, Pei-Feng; Hsieh, Yao-Dung; Lin, Ya-Ching; Two, Aimee; Shu, Chih-Wen; Huang, Chun-Ming

    2015-01-01

    Acne vulgaris, a multi-factorial disease, is one of the most common skin diseases, affecting an estimated 80% of Americans at some point during their lives. The gram-positive and anaerobic Propionibacterium acnes (P. acnes) bacterium has been implicated in acne inflammation and pathogenesis. Therapies for acne vulgaris using antibiotics generally lack bacterial specificity, promote the generation of antibiotic-resistant bacterial strains, and cause adverse effects. Immunotherapy against P. acnes or its antigens (sialidase and CAMP factor) has been demonstrated to be effective in mice, attenuating P. acnes-induced inflammation; thus, this method may be applied to develop a potential vaccine targeting P. acnes for acne vulgaris treatment. This review summarizes reports describing the role of P. acnes in the pathogenesis of acne and various immunotherapy-based approaches targeting P. acnes, suggesting the potential effectiveness of immunotherapy for acne vulgaris as well as P. acnes-associated diseases.

  13. Acne Facts and Stats

    Science.gov (United States)

    ... peels and skin fillers provide safe and effective treatments for acne scarring. Since acne scars are unique in their appearance and often have complex characteristics, patients should consult their dermatologist to ... for the most successful result. References 1. ...

  14. Epidemiology of acne vulgaris.

    Science.gov (United States)

    Bhate, K; Williams, H C

    2013-03-01

    Despite acne being an almost universal condition in younger people, relatively little is known about its epidemiology. We sought to review what is known about the distribution and causes of acne by conducting a systematic review of relevant epidemiological studies. We searched Medline and Embase to the end of November 2011. The role of Propionibacterium acnes in pathogenesis is unclear: antibiotics have a direct antimicrobial as well as an anti-inflammatory effect. Moderate-to-severe acne affects around 20% of young people and severity correlates with pubertal maturity. Acne may be presenting at a younger age because of earlier puberty. It is unclear if ethnicity is truly associated with acne. Black individuals are more prone to postinflammatory hyperpigmentation and specific subtypes such as 'pomade acne'. Acne persists into the 20s and 30s in around 64% and 43% of individuals, respectively. The heritability of acne is almost 80% in first-degree relatives. Acne occurs earlier and is more severe in those with a positive family history. Suicidal ideation is more common in those with severe compared with mild acne. In the U.S.A., the cost of acne is over 3 billion dollars per year in terms of treatment and loss of productivity. A systematic review in 2005 found no clear evidence of dietary components increasing acne risk. One small randomized controlled trial showed that low glycaemic index (GI) diets can lower acne severity. A possible association between dairy food intake and acne requires closer scrutiny. Natural sunlight or poor hygiene are not associated. The association between smoking and acne is probably due to confounding. Validated core outcomes in future studies will help in combining future evidence. © 2012 The Authors. BJD © 2012 British Association of Dermatologists.

  15. Acne vulgaris: endocriene aspecten

    NARCIS (Netherlands)

    Dekkers, O. M.; Thio, B. H.; Romijn, J. A.; Smit, J. W. A.

    2006-01-01

    Androgens play an important part in the development of acne vulgaris. Androgen levels in patients with acne are higher than those in controls and people with the androgen insensitivity syndrome do not develop acne. Local factors other than androgen plasma levels, also play a part in the development

  16. Acne - self-care

    Science.gov (United States)

    Acne vulgaris - self-care; Cystic acne - self-care; Pimples - self-care; Zits - self-care ... If daily skin care does not clear up blemishes, try over-the-counter acne medicines that you apply to your skin. These products ...

  17. What Is Acne?

    Science.gov (United States)

    ... Health Topics English Español 한국어 繁體中文 tiếng Việt Acne Basics In-Depth Download Download EPUB Download PDF What is it? Points To Remember About Acne Doctors don’t know what causes acne, but ...

  18. Identifying acne treatment uncertainties via a James Lind Alliance Priority Setting Partnership

    National Research Council Canada - National Science Library

    Layton, Alison; Eady, E Anne; Peat, Maggie; Whitehouse, Heather; Levell, Nick; Ridd, Matthew; Cowdell, Fiona; Patel, Mahenda; Andrews, Stephen; Oxnard, Christine; Fenton, Mark; Firkins, Lester

    2015-01-01

    The Acne Priority Setting Partnership (PSP) was set up to identify and rank treatment uncertainties by bringing together people with acne, and professionals providing care within and beyond the National Health Service (NHS...

  19. 77 FR 65581 - Verizon Business Networks Services, Inc., Senior Analyst, Service Program Delivery (SA-SPD...

    Science.gov (United States)

    2012-10-29

    ... Employment and Training Administration Verizon Business Networks Services, Inc., Senior Analyst, Service..., 2012, applicable to workers and former workers of Verizon Business Network Services, Inc., Senior... hereby issued as follows: ] All workers of Verizon Business Network Services, Inc., Senior Analyst...

  20. Acne in women.

    Science.gov (United States)

    Ramos-e-Silva, M; Ramos-e-Silva, S; Carneiro, S

    2015-07-01

    This review focuses on the subject of acne in women, a disease that is increasingly common and that can also affect men. Adult acne differs from the type of acne that occurs in teenagers, and it may persist beyond adolescence or have its onset at an older age (adult-onset acne or late acne). Acne can have a negative impact on the quality of life of patients at any age, leading to a negative body image and decrease in self-esteem, and in older patients it can result in discrimination in the workplace and in other social environments. Acne in women must be understood as a specific problem, and here we discuss the pathogenesis, clinical presentation, psychology and treatment of this very prevalent problem. © 2015 British Association of Dermatologists.

  1. Network and Service Monitoring in Heterogeneous Home Networks

    NARCIS (Netherlands)

    Delphinanto, A.

    2012-01-01

    Home networks are becoming dynamic and technologically heterogeneous. They consist of an increasing number of devices which offer several functionalities and can be used for many different services. In the home, these devices are interconnected using a mixture of networking technologies (for

  2. Can Acne Scars Be Removed?

    Science.gov (United States)

    ... Arrhythmias Abuse Love and Romance Understanding Other People Can Acne Scars Be Removed? KidsHealth > For Teens > Can Acne Scars Be Removed? Print A A A ... acné? Different Types of Acne Scars from acne can seem like double punishment — first you had to ...

  3. Acne: more than skin deep

    OpenAIRE

    Ayer, J; Burrows, N

    2006-01-01

    Acne is one of the most prevalent skin conditions affecting teenagers. It is a disease of the pilosebaceous unit. Blockage of sebaceous glands and colonisation with Proionobacterium acnes leads to acne. Grading the severity of acne helps to determine the appropriate treatment. Treatment of acne should be started as early as possible to minimise the risk of scarring and adverse psychological effects. It should be tailored to the individual patient, the type of acne, its severity, the patient's...

  4. Hormonal therapy for acne.

    Science.gov (United States)

    George, Rosalyn; Clarke, Shari; Thiboutot, Diane

    2008-09-01

    Acne affects more than 40 million people, of which more than half are women older than 25 years of age. These women frequently fail traditional therapy and have high relapse rates even after isotretinoin. Recent advances in research have helped to delineate the important role hormones play in the pathogenesis of acne. Androgens such as dihydrotestosterone and testosterone, the adrenal precursor dehydroepiandrosterone sulfate, estrogens, growth hormone, and insulin-like growth factors may all contribute to the development of acne. Hormonal therapy remains an important part of the arsenal of acne treatments available to the clinician. Women dealing with acne, even those without increased serum androgens, may benefit from hormonal treatments. The mainstays of hormonal therapy include oral contraceptives and antiandrogens such as spironolactone, cyproterone acetate, or flutamide. In this article, we discuss the effects of hormones on the pathogenesis of acne, evaluation of women with suspected endocrine abnormalities, and the myriad of treatment options available.

  5. Acne fulminans incapacitante Disabling Acne Fulminans

    Directory of Open Access Journals (Sweden)

    Tiago Pina Zanelato

    2011-08-01

    Full Text Available Acne fulminans é uma manifestação rara, que pode ocorrer durante a evolução da acne vulgar, principalmente, em adolescentes masculinos. Uso de isotretinoína, testosterona, e reações imunológicas exacerbadas no organismo são desencadeantes relacionados. Sinais, sintomas e alterações laboratoriais como: febre, hepatomegalia, poliartralgia, leucocitose, plaquetose, aumento de provas inflamatórias e transaminases, são característicos. A cintilografia óssea pode detectar lesões líticas em vários sítios do esqueleto. O tratamento é realizado com prednisolona, isotretinoína e antibióticos se infecções secundárias. Este caso relata um paciente masculino com diagnóstico de acne grau III, que desenvolveu acne fulminans e sacroileíte bilateral, com incapacidade de deambulação após início de terapia com isotretinoínaAcne fulminans is a rare manifestation that may occur during the evolution of acne vulgaris primarily in male adolescents. Use of isotretinoin, testosterone, and exacerbated immune responses in the body are related triggers. Signs, symptoms and laboratory findings such as fever, hepatomegaly, polyarthralgia, leukocytosis, plaquetose, increased inflammatory markers and transaminases, are characteristic. A bone scan can detect osteolytic lesions in multiple skeletal sites. The treatment is performed with prednisolone, isotretinoin and antibiotics if secondary infection is present. This case describes a male patient with a diagnosis of grade III acne, who developed acne fulminans and bilateral sacroiliitis with inability to ambulate, after initiation of therapy with isotretinoin

  6. Service network analysis for agricultural mental health

    Directory of Open Access Journals (Sweden)

    Fuller Jeffrey D

    2009-05-01

    Full Text Available Abstract Background Farmers represent a subgroup of rural and remote communities at higher risk of suicide attributed to insecure economic futures, self-reliant cultures and poor access to health services. Early intervention models are required that tap into existing farming networks. This study describes service networks in rural shires that relate to the mental health needs of farming families. This serves as a baseline to inform service network improvements. Methods A network survey of mental health related links between agricultural support, health and other human services in four drought declared shires in comparable districts in rural New South Wales, Australia. Mental health links covered information exchange, referral recommendations and program development. Results 87 agencies from 111 (78% completed a survey. 79% indicated that two thirds of their clients needed assistance for mental health related problems. The highest mean number of interagency links concerned information exchange and the frequency of these links between sectors was monthly to three monthly. The effectiveness of agricultural support and health sector links were rated as less effective by the agricultural support sector than by the health sector (p Conclusion Aligning with agricultural agencies is important to build effective mental health service pathways to address the needs of farming populations. Work is required to ensure that these agricultural support agencies have operational and effective links to primary mental health care services. Network analysis provides a baseline to inform this work. With interventions such as local mental health training and joint service planning to promote network development we would expect to see over time an increase in the mean number of links, the frequency in which these links are used and the rated effectiveness of these links.

  7. Hormone therapy in acne

    Directory of Open Access Journals (Sweden)

    Chembolli Lakshmi

    2013-01-01

    Full Text Available Underlying hormone imbalances may render acne unresponsive to conventional therapy. Relevant investigations followed by initiation of hormonal therapy in combination with regular anti-acne therapy may be necessary if signs of hyperandrogenism are present. In addition to other factors, androgen-stimulated sebum production plays an important role in the pathophysiology of acne in women. Sebum production is also regulated by other hormones, including estrogens, growth hormone, insulin, insulin-like growth factor-1, glucocorticoids, adrenocorticotropic hormone, and melanocortins. Hormonal therapy may also be beneficial in female acne patients with normal serum androgen levels. An understanding of the sebaceous gland and the hormonal influences in the pathogenesis of acne would be essential for optimizing hormonal therapy. Sebocytes form the sebaceous gland. Human sebocytes express a multitude of receptors, including receptors for peptide hormones, neurotransmitters and the receptors for steroid and thyroid hormones. Various hormones and mediators acting through the sebocyte receptors play a role in the orchestration of pathogenetic lesions of acne. Thus, the goal of hormonal treatment is a reduction in sebum production. This review shall focus on hormonal influences in the elicitation of acne via the sebocyte receptors, pathways of cutaneous androgen metabolism, various clinical scenarios and syndromes associated with acne, and the available therapeutic armamentarium of hormones and drugs having hormone-like actions in the treatment of acne.

  8. Sonography of acne vulgaris.

    Science.gov (United States)

    Wortsman, Ximena; Claveria, Pedro; Valenzuela, Fernando; Molina, Maria Teresa; Wortsman, Jacobo

    2014-01-01

    The purpose of this study was to assess the sonographic morphology of the clinical and subclinical pathology of facial acne vulgaris. We studied patients with facial acne vulgaris diagnosed by certified dermatologists, and using a standardized protocol for sonographic examinations, we sequentially described the sonographic pathomorphologic characteristics. Lesions of particular interest to the referring clinician were also analyzed separately. Additionally, acne involvement was staged clinically and sonographically (SOS-Acne) using morphologic definitions of the relevant lesions and predefined scoring systems for gradation of the severity of acne lesions. A total of 245 acne lesions in 20 consecutive patients were studied. Sonographic abnormalities consisted of pseudocysts, folliculitis, fistulas, and calcinosis. Most conditions were subclinical and mostly due to lesion extensions deep into the dermis and hypodermis (52% of pseudocysts and 68% of fistulas). The statistical concordance between acne severity scores assigned by two separate clinicians was strong (κ = 0.8020), but the corresponding sonographic scores generally showed more severe and clinically occult involvement. Facial acne vulgaris often involves deeper tissues, beyond the reach of the spatially restricted clinical examination; these subclinical conditions can be detected and defined with sonography. Additionally, acne vulgaris is amenable to sonographic scoring.

  9. Disabling acne fulminans.

    Science.gov (United States)

    Zanelato, Tiago Pina; Gontijo, Gabriela Maria Abreu; Alves, Célia Antônia Xavier de Moares; Pinto, Jacqueline Campoi Calvo Lopes; Cunha, Paulo Rowilson

    2011-01-01

    Acne fulminans is a rare manifestation that may occur during the evolution of acne vulgaris primarily in male adolescents. Use of isotretinoin, testosterone, and exacerbated immune responses in the body are related triggers. Signs, symptoms and laboratory findings such as fever, hepatomegaly, polyarthralgia, leukocytosis, plaquetose, increased inflammatory markers and transaminases, are characteristic. A bone scan can detect osteolytic lesions in multiple skeletal sites. The treatment is performed with prednisolone, isotretinoin and antibiotics if secondary infection is present. This case describes a male patient with a diagnosis of grade III acne, who developed acne fulminans and bilateral sacroiliitis with inability to ambulate, after initiation of therapy with isotretinoin.

  10. Wireless intelligent network: infrastructure before services?

    Science.gov (United States)

    Chu, Narisa N.

    1996-01-01

    The Wireless Intelligent Network (WIN) intends to take advantage of the Advanced Intelligent Network (AIN) concepts and products developed from wireline communications. However, progress of the AIN deployment has been slow due to the many barriers that exist in the traditional wireline carriers' deployment procedures and infrastructure. The success of AIN has not been truly demonstrated. The AIN objectives and directions are applicable to the wireless industry although the plans and implementations could be significantly different. This paper points out WIN characteristics in architecture, flexibility, deployment, and value to customers. In order to succeed, the technology driven AIN concept has to be reinforced by the market driven WIN services. An infrastructure suitable for the WIN will contain elements that are foreign to the wireline network. The deployment process is expected to seed with the revenue generated services. Standardization will be achieved by simplifying and incorporating the IS-41C, AIN, and Intelligent Network CS-1 recommendations. Integration of the existing and future systems impose the biggest challenge of all. Service creation has to be complemented with service deployment process which heavily impact the carriers' infrastructure. WIN deployment will likely start from an Intelligent Peripheral, a Service Control Point and migrate to a Service Node when sufficient triggers are implemented in the mobile switch for distributed call control. The struggle to move forward will not be based on technology, but rather on the impact to existing infrastructure.

  11. Can I Prevent Acne?

    Science.gov (United States)

    ... Arrhythmias Abuse Love and Romance Understanding Other People Can I Prevent Acne? KidsHealth > For Teens > Can I Prevent Acne? Print A A A en ... excess surface oils and dead skin cells that can clog your pores), but washing too much can ...

  12. [Charles Bukowski's acne].

    Science.gov (United States)

    Bahmer, F A; Bahmer, J A

    2012-04-01

    In his autobiography, Charles Bukowski (1920-1994) describes his severe acne conglobata, his experience with therapy, family conflicts and emotional tension. Despite the stigmatization by his acne scars, Bukowski became a philobatic writer and a true chronist of the American way of life in the second half of the 20th century, writing in a coarse and obscene language.

  13. Integrating Network Management for Cloud Computing Services

    Science.gov (United States)

    2015-06-01

    DeviceConfigIsControl- lable is calculated based on whether the device is powered up, whether the device can be reachable via SSH /Telnet from the management network...lines of C# and C++ code, plus a number of internal libraries . At its core, it is a highly-available RESTful web service with persistent storage. Below

  14. Jitter reduction in Differentiated Services (Diffserv) networks

    NARCIS (Netherlands)

    Karagiannis, Georgios; Rexhepi, Vlora

    2005-01-01

    A method and a computer program for reducing jitter in IP packet transmission in a Diffserv network having ingress and egress Border Routers and using premium service, expedited forwarding and source route option, recognize incoming packets which have firm jitter requirements. The program verifies

  15. Social Networking Services in E-Learning

    Science.gov (United States)

    Weber, Peter; Rothe, Hannes

    2016-01-01

    This paper is a report on the findings of a study conducted on the use of the social networking service NING in a cross-location e-learning setting named "Net Economy." We describe how we implemented NING as a fundamental part of the setting through a special phase concept and team building approach. With the help of user statistics, we…

  16. Automated Network Catalog Products and Services

    Science.gov (United States)

    Freedman, Maurice J.

    1976-01-01

    Four categories of automated network catalog products and services are examined. The advantages and disadvantages of (1) the on-line cathode-ray-tube (CRT) display, (2) the line-printer produced card, (3) the photo-composed book catalog or catalog card, and (4) computer-based microforms are all reviewed. (Author)

  17. Service Creation and Deployment in Converged Networks

    DEFF Research Database (Denmark)

    Soler, José

    This monograph (Early Experiences related to Service Creation & Deployment in Converged Networks) presents different experiences related to architectures and mechanisms for deployment of telephony services, understood as especial features complementing the basic voice service. The context...... and Future Converged Networks”, carried out at the Technical University of Denmark in the period [April 2002-April 2005]. Even though the technologies presented in the text have evolved from that period until now, the presented scenarios and setups are still valid as interesting initial steps in the realm....

  18. Management strategies for acne vulgaris

    Science.gov (United States)

    Whitney, Kristen M; Ditre, Chérie M

    2011-01-01

    Clinical question: What are the most effective treatment(s) for mild, moderate, severe, and hormonally driven acne? Results: Mild acne responds favorably to topical treatments such as benzoyl peroxide, salicylic acid, and a low-dose retinoid. Moderate acne responds well to combination therapy comprising-topical benzoyl peroxide, antibiotics, and/or retinoids, as well as oral antibiotics in refractory cases and oral contraceptive pills for female acne patients. Severe nodulocystic acne vulgaris responds best to oral isotretinoin therapy. In female patients with moderate to severe acne, facial hair, loss of scalp hair and irregular periods, polycystic ovarian syndrome should be considered and appropriate treatment with hormonal modulation given. Adjunctive procedures can also be considered for all acne patients. Implementation: Pitfalls to avoid when treating acne: treatment of acne in women of child-bearing age; familiarization of all acne treatments in order to individualize management for patients; indications for specialist referral. PMID:21691566

  19. Requirements for a network storage service

    Science.gov (United States)

    Kelly, Suzanne M.; Haynes, Rena A.

    1992-01-01

    Sandia National Laboratories provides a high performance classified computer network as a core capability in support of its mission of nuclear weapons design and engineering, physical sciences research, and energy research and development. The network, locally known as the Internal Secure Network (ISN), was designed in 1989 and comprises multiple distributed local area networks (LAN's) residing in Albuquerque, New Mexico and Livermore, California. The TCP/IP protocol suite is used for inner-node communications. Scientific workstations and mid-range computers, running UNIX-based operating systems, compose most LAN's. One LAN, operated by the Sandia Corporate Computing Directorate, is a general purpose resource providing a supercomputer and a file server to the entire ISN. The current file server on the supercomputer LAN is an implementation of the Common File System (CFS) developed by Los Alamos National Laboratory. Subsequent to the design of the ISN, Sandia reviewed its mass storage requirements and chose to enter into a competitive procurement to replace the existing file server with one more adaptable to a UNIX/TCP/IP environment. The requirements study for the network was the starting point for the requirements study for the new file server. The file server is called the Network Storage Services (NSS) and is requirements are described in this paper. The next section gives an application or functional description of the NSS. The final section adds performance, capacity, and access constraints to the requirements.

  20. Services supporting collaborative alignment of engineering networks

    Science.gov (United States)

    Jansson, Kim; Uoti, Mikko; Karvonen, Iris

    2015-08-01

    Large-scale facilities such as power plants, process factories, ships and communication infrastructures are often engineered and delivered through geographically distributed operations. The competencies required are usually distributed across several contributing organisations. In these complicated projects, it is of key importance that all partners work coherently towards a common goal. VTT and a number of industrial organisations in the marine sector have participated in a national collaborative research programme addressing these needs. The main output of this programme was development of the Innovation and Engineering Maturity Model for Marine-Industry Networks. The recently completed European Union Framework Programme 7 project COIN developed innovative solutions and software services for enterprise collaboration and enterprise interoperability. One area of focus in that work was services for collaborative project management. This article first addresses a number of central underlying research themes and previous research results that have influenced the development work mentioned above. This article presents two approaches for the development of services that support distributed engineering work. Experience from use of the services is analysed, and potential for development is identified. This article concludes with a proposal for consolidation of the two above-mentioned methodologies. This article outlines the characteristics and requirements of future services supporting collaborative alignment of engineering networks.

  1. Seismological data networks and services in Europe

    Science.gov (United States)

    Spinuso, A.; Kamb, L.; Trani, L.; Frobert, L.

    2011-12-01

    The Seismic Data Portal (http://www.seismicportal.eu) provides a collection of tools to discover, visualize, and access a variety of seismological data sets, including earthquake parameters, broadband and accelerometric data, European tomography, and historical earthquake catalogs. The Portal was developed as part of the Network of Research Infrastructures for European Seismology project, which was funded under the 6th European Framework Programme to integrate data and service resources for the seismological community. The NERIES project brought together 25 participating institutions and organizations under 19 work packages to produce numerous scientific results through coordinated research, development, networking, and integration activities. The Seismic Data Portal provides a single point of access to the heterogeneous and distributed data sets developed or made available through the NERIES project. These tools operate in a coordinated manner to provide a cohesive distributed search environment, linking data search and access across multiple data providers. Through interactive, map-based tools, a researcher is able to build queries linking event parametric data with seismological broadband or accelerometric waveform data. The Portal architecture is based on a suite of standards and standard technologies, allowing interoperability between tools and the integration of new tools as they become available. The data tools are supported by web services running at their respective data centers. These web services provide the programmatic interface between the interactive, web-based tools, and the underlying data archives. Moreover they are in turn available to external applications, allowing direct programmatic queries to the data archives. Work on the Data Portal, access tools, and services architecture will continue under other EU funded projects. The NERA, Network of European Research Infrastructures for Earthquake Risk Assessment and Mitigation project, funded under

  2. Requirements for a Network Storage Service in a supercomputer environment

    Energy Technology Data Exchange (ETDEWEB)

    Kelly, S.M.

    1991-09-26

    Sandia National Laboratories has completed a requirements study for a networked mass storage system. The areas of user functionality, network connectivity, and performance were analyzed to determine specifications for a Network Storage Service to operate in supercomputer environment. 4 refs.

  3. Lipid Mediators in Acne

    Directory of Open Access Journals (Sweden)

    Monica Ottaviani

    2010-01-01

    Full Text Available Multiple factors are involved in acne pathogenesis, and sebum secretion is one of the main ones. The role sebum plays in acne development has not been completely elucidated yet; however, increasing amounts of data seem to confirm the presence of alterations in sebum from acne patients. Altered ratio between saturated and unsaturated fatty acids has been indicated as an important feature to be considered in addition to the altered amount of specific fatty acids such as linoleic acid. Furthermore, particular attention has been focused on squalene peroxide that seems to be able to induce an inflammatory response beyond cytotoxicity and comedones formation. Moreover, recent data suggest that lipid mediators are able to interfere with sebocytes differentiation and sebogenesis through the activation of pathways related to peroxisome proliferators-activated receptors. Understanding the factors and mechanisms that regulate sebum production is needed in order to identify novel therapeutic strategies for acne treatment.

  4. Acne scar subcision

    Directory of Open Access Journals (Sweden)

    B S Chandrashekar

    2010-01-01

    Full Text Available Subcision is a simple and safe office surgery procedure for treatment of depressed acne scars. It can easily be combined with other treatments such as laser, dermaroller and scar revisions for maximum efficacy.

  5. Bacteriophages Infecting Propionibacterium acnes

    Directory of Open Access Journals (Sweden)

    Holger Brüggemann

    2013-01-01

    Full Text Available Viruses specifically infecting bacteria, or bacteriophages, are the most common biological entity in the biosphere. As such, they greatly influence bacteria, both in terms of enhancing their virulence and in terms of killing them. Since the first identification of bacteriophages in the beginning of the 20th century, researchers have been fascinated by these microorganisms and their ability to eradicate bacteria. In this review, we will cover the history of the Propionibacterium acnes bacteriophage research and point out how bacteriophage research has been an important part of the research on P. acnes itself. We will further discuss recent findings from phage genome sequencing and the identification of phage sequence signatures in clustered regularly interspaced short palindromic repeats (CRISPRs. Finally, the potential to use P. acnes bacteriophages as a therapeutic strategy to combat P. acnes-associated diseases will be discussed.

  6. Optical Network as a Service for Service Function Chaining across Datacenters

    DEFF Research Database (Denmark)

    Mehmeri, Victor; Wang, Xi; Zhang, Qiong

    2017-01-01

    We present the SPN OS, a Network-as-a-Service orchestration platform for NFV/SDN integrated service provisioning across multiple datacenters over packet/optical networks. Our prototype showcases template-driven service function chaining and high-level network programming-based optical networking....

  7. Service-oriented Software Defined Optical Networks for Cloud Computing

    Science.gov (United States)

    Liu, Yuze; Li, Hui; Ji, Yuefeng

    2017-10-01

    With the development of big data and cloud computing technology, the traditional software-defined network is facing new challenges (e.g., ubiquitous accessibility, higher bandwidth, more flexible management and greater security). This paper proposes a new service-oriented software defined optical network architecture, including a resource layer, a service abstract layer, a control layer and an application layer. We then dwell on the corresponding service providing method. Different service ID is used to identify the service a device can offer. Finally, we experimentally evaluate that proposed service providing method can be applied to transmit different services based on the service ID in the service-oriented software defined optical network.

  8. Acne: Diet and acnegenesis

    Directory of Open Access Journals (Sweden)

    F William Danby

    2011-01-01

    Full Text Available Acne is a manifestation of hormonal overstimulation of the pilosebaceous units of genetically susceptible individuals. Endogenous reproductive and growth hormones, exogenous reproductive hormones, insulin and endogenous insulin-like growth hormone-1, sourced from and stimulated by dairy and high glycemic load foods, all appear to contribute to this overstimulation. A postulated molecular mechanism linking food and acne is reported and integrated into the clinical picture.

  9. Acne and diet.

    Science.gov (United States)

    Wolf, Ronni; Matz, Hagit; Orion, Edith

    2004-01-01

    Forbidden foods? "The first law of dietetics seems to be: If it tastes good, it's bad for you" (Isaac Asimov, Russian-born biochemist and science fiction writer). This was essentially the Magna Carta for dermatologists of the 1950s: anything coveted by the teenage palate was suspect for morning after acne. Today, half a century later, although the slant has shifted away for this line of thinking in our dermatologic textbooks, several articles on the beliefs and perceptions of acne patients showed that nothing much has changed and that they expect us to give them detailed instructions of what "acne-related" foods they should avoid. In one such study(1), diet was the third most frequently implicated factor (after hormones and genetics) as the cause of the disease, with 32% of the respondents selecting diet as the main cause, and 44% thinking that foods aggravate acne. In another study that analyzed knowledge about causes of acne among English teenagers, 11% of the responders blamed greasy food as the main cause of the disease(2), whereas in another study found that 41% of final-year medical students of the University of Melbourne chose diet as an important factor of acne exacerbation on a final examination.(3)

  10. The CORS Network Products and Services

    Science.gov (United States)

    Sella, G.; Snay, R.; Cline, M.; Don, H.

    2008-12-01

    The National Geodetic Survey (NGS) is responsible for defining, providing access and maintaining the National Spatial Reference System (NSRS) which is the legally binding reference frame for the civilian sector of the US Federal Government, and most of the public. With the increasing access to space geodetic data sources, especially GPS, NGS has been transitioning to a space based NSRS. In 1994 NGS created the Continuously Operating Reference Station (CORS) network as a partnership with site operators of continuously operating GNSS sites who were willing to share their data with the public. The network currently contains ~1,200 stations, located mostly in the United States, and is growing at ~ 200 stations a year. The CORS network is particularly dense in the eastern United States, and its GPS observations are used extensively by researchers. NGS is taking a number of steps to improve its CORS related products and services including: 1) More stringent requirements for constructing new CORS as well as operating existing stations, 2) Investigating biases affecting GPS observations collected at CORS, in particular the effects of multipath, and 3) Improving processing software of GPS observables to compute orbits and coordinate computation. This effort has been emphasized because NGS is both an IGS analysis center and the current IGS analysis center coordinator. NGS is reprocessing all CORS data collected since 1994 with the goal of updating the current legally binding geometric reference frame known as NAD83. NGS has also improved and expanded its post-processing web service tools, including the Online Positioning User Service (OPUS). Lastly NGS is now operating a prototype real time GNSS data-delivery service broadcasting in RTCM format via NTRIP.

  11. Integrated service resource reservation using queueing networks theory

    DEFF Research Database (Denmark)

    Brewka, Lukasz Jerzy; Iversen, Villy Bæk; Kardaras, Georgios

    2014-01-01

    This study analyses multi-server multi-service queueing networks with service protection. To guarantee each service a certain quality-of-service and at the same time ensure high utilisation of servers, a minimum capacity is reserved each service. In addition, all services share the remaining non...

  12. Evaluation and Management of Acne.

    Science.gov (United States)

    Botros, Paul A; Tsai, Gary; Pujalte, George G A

    2015-12-01

    Acne is a common complaint in the primary care clinics. It has not only physical implications but also psychological. This article discusses the epidemiology, pathophysiology, and criteria for making the diagnosis. It also discusses endocrine disorders that may be the cause of acne. Treatment and management are discussed by subtype. Acne mechanica or sports-related acne is also discussed. Copyright © 2015 Elsevier Inc. All rights reserved.

  13. Neonatal and infantile acne vulgaris: an update.

    Science.gov (United States)

    Serna-Tamayo, Cristian; Janniger, Camila K; Micali, Giuseppe; Schwartz, Robert A

    2014-07-01

    Acne may present in neonates, infants, and small children. Neonatal and infantile acne vulgaris are not considered to be rare. The presentation of acne in this patient population sometimes represents virilization and may portend later development of severe adolescent acne. Neonatal and infantile acne vulgaris must be distinguished from other cutaneous disorders seen in newborns and infants. Infantile acne tends to be more pleomorphic and inflammatory, thus requiring more vigorous therapy than neonatal acne.

  14. Diagnosing degradation of services in hybrid wireless tactical networks

    Science.gov (United States)

    Tati, Srikar; Novotny, Petr; Ko, Bong Jun; Wolf, Alexander; Swami, Ananthram; La Porta, Thomas

    2013-05-01

    In this paper, we consider a problem related to service management and deployment in tactical military networks. Tactical networks are typically hybrid wireless networks in which there are both static and mobile nodes with several wireless interfaces, such as 802.11, 3G, satellite, etc. In tactical networks, performance degradation in services could prove fatal, so it must be diagnosed quickly. This degradation could be due to mobility or bottlenecks in capacity at network layer. We provide a cross-layer framework to detect and diagnose these causes of performance degradation as part of service management; it includes a monitoring model of services and a network model for hybrid wireless networks. In addition, we give a working example in tactical military networks to illustrate our framework. We provide an experimental setup to simulate our hybrid wireless tactical network scenario along with preliminary results.

  15. Performance Evaluation of Resilience using Service Relocation for GMPLS Networks

    DEFF Research Database (Denmark)

    Wessing, Henrik; Herrmann, Sven; Ruepp, Sarah Renée

    2015-01-01

    path when providing resiliency to cloud services in the network. The control plane of a GMPLSenabled optical network is simulated, thus evaluating the proposed Path Computation Element architecture for service relocation. The results show that for increased offered traffic in the network, the overall...

  16. Quality of service in optical packet switched networks

    CERN Document Server

    Rahbar, Akbar G

    2015-01-01

    This book is a comprehensive study on OPS networks, its architectures, and developed techniques for improving its quality of switching and managing quality of service.  The book includes: Introduction to OPS networks, OOFDM networks, GMPLS-enabled optical networks, QoS in OPS networks Hybrid contention avoidance/resolution schemes in both long-haul and metro optical networks Hybrid optical switching schemes

  17. Evidence on acne therapy

    Directory of Open Access Journals (Sweden)

    Caroline Sousa Costa

    Full Text Available Among the current treatments available for acne vulgaris, many widely practiced options lack support from studies at the best level of scientific evidence. The aim of this narrative review was to present the very latest information on topical and systemic treatments for acne vulgaris. Information from systematic reviews and well-designed clinical trials, obtained through a systematic search of the major medical databases, is emphasized. There are important issues regarding the clinical management of acne that still lack consistent grounding in scientific evidence. Among these are the optimum dose and duration of treatment with oral antibiotics that can be given without inducing bacterial resistance, and the safety of oral isotretinoin.

  18. Service delivery aspects in a reconfigurable photonic access network

    NARCIS (Netherlands)

    Roy, R.; Manhoudt, Gert; van Etten, Wim

    2008-01-01

    We discuss service delivery aspects in a reconfigurable photonic access network. The network is viewed as a stack of logical PONs in which a DWDM overlay is used over TDM PONs operating in their native format. The use of optical routers in the network allows for a dynamic change in the network

  19. [Cosmetic treatments and acne].

    Science.gov (United States)

    Poli, Florence

    2002-04-15

    Cosmetic products contribute to the efficacy of anti-acneic treatment. Cleaning bars without soap and lotions are to be preferred to soaps. Morning application of moisturizing creams compensate for dryness and irritation induced by topical treatment. Some of these cosmetic products may have a limited efficacy of the shiny appearance and/or acne lesions. Scrubs, abrasive sponges, masks and patches have a very limited usefulness. Make up and camouflage techniques are authorized, provided that the products have been tested non comedogenic and non acne-genic.

  20. Disabling Acne Fulminans

    OpenAIRE

    Tiago Pina Zanelato; Gabriela Maria Abreu Gontijo; Célia Antônia Xavier de Moares Alves; Jacqueline Campoi Calvo Lopes Pinto; Paulo Rowilson Cunha

    2011-01-01

    Acne fulminans é uma manifestação rara, que pode ocorrer durante a evolução da acne vulgar, principalmente, em adolescentes masculinos. Uso de isotretinoína, testosterona, e reações imunológicas exacerbadas no organismo são desencadeantes relacionados. Sinais, sintomas e alterações laboratoriais como: febre, hepatomegalia, poliartralgia, leucocitose, plaquetose, aumento de provas inflamatórias e transaminases, são característicos. A cintilografia óssea pode detectar lesões líticas em vários s...

  1. Management strategies for acne vulgaris

    Directory of Open Access Journals (Sweden)

    Whitney KM

    2011-04-01

    Full Text Available Kristen M Whitney1, Chérie M Ditre21Philadelphia College of Osteopathic Medicine, Philadelphia, PA, USA; 2Skin Enhancement Center and Cosmetic Dermatology, Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, PA, USADate of preparation: 30th November 2010Conflicts of interest: None declaredClinical question: What are the most effective treatment(s for mild, moderate, severe, and hormonally driven acne?Results: Mild acne responds favorably to topical treatments such as benzoyl peroxide, salicylic acid, and a low-dose retinoid. Moderate acne responds well to combination therapy comprising-topical benzoyl peroxide, antibiotics, and/or retinoids, as well as oral antibiotics in refractory cases and oral contraceptive pills for female acne patients. Severe nodulocystic acne vulgaris responds best to oral isotretinoin therapy. In female patients with moderate to severe acne, facial hair, loss of scalp hair and irregular periods, polycystic ovarian syndrome should be considered and appropriate treatment with hormonal modulation given. Adjunctive procedures can also be considered for all acne patients.Implementation: Pitfalls to avoid when treating acne: treatment of acne in women of childbearing age; familiarization of all acne treatments in order to individualize management for patients; indications for specialist referral.Keywords: acne vulgaris, benzoyl peroxide, retinoids, antibiotics, light and laser therapy, photodynamic therapy, photopneumatic therapy, chemical peels

  2. Software-Programmed Optical Networking with Integrated NFV Service Provisioning

    DEFF Research Database (Denmark)

    Mehmeri, Victor; Wang, Xi; Basu, Shrutarshi

    2017-01-01

    We showcase demonstrations of “program & compile” styled optical networking as well as open platforms & standards based NFV service provisioning using a proof-of-concept implementation of the Software-Programmed Networking Operating System (SPN OS).......We showcase demonstrations of “program & compile” styled optical networking as well as open platforms & standards based NFV service provisioning using a proof-of-concept implementation of the Software-Programmed Networking Operating System (SPN OS)....

  3. Authentication Issues in Multi-Service Residential Access Networks

    OpenAIRE

    Rossebo, Judith; Ronan, John; Walsh, Kristian

    2003-01-01

    Multi-service residential access networks allow residential customers to choose amongst a variety of service offerings, over a range of Core Networks and subject to user requirements such as QoS, mobility, cost and availability. These issues place requirements on authentication for network access, with a need for mutual authentication of the residential gateway (RG) to the local access point (LAP). The EU-IST project TORRENT is building a testbed providing for multi-service residential access...

  4. Driving demand for broadband networks and services

    CERN Document Server

    Katz, Raul L

    2014-01-01

    This book examines the reasons why various groups around the world choose not to adopt broadband services and evaluates strategies to stimulate the demand that will lead to increased broadband use. It introduces readers to the benefits of higher adoption rates while examining the progress that developed and emerging countries have made in stimulating broadband demand. By relying on concepts such as a supply and demand gap, broadband price elasticity, and demand promotion, this book explains differences between the fixed and mobile broadband demand gap, introducing the notions of substitution and complementarity between both platforms. Building on these concepts, ‘Driving Demand for Broadband Networks and Services’ offers a set of best practices and recommendations aimed at promoting broadband demand.  The broadband demand gap is defined as individuals and households that could buy a broadband subscription because they live in areas served by telecommunications carriers but do not do so because of either ...

  5. Recent Themes in Social Networking Service Research.

    Directory of Open Access Journals (Sweden)

    John S Liu

    Full Text Available The body of literature addressing the phenomenon related to social networking services (SNSs has grown rather fast recently. Through a systematic and quantitative approach, this study identifies the recent SNS research themes, which are the issues discussed by a coherent and growing subset of this literature. A set of academic articles retrieved from the Web of Science database is used as the basis for uncovering the recent themes. We begin the analysis by constructing a citation network which is further separated into groups after applying a widely used clustering method. The resulting clusters all consist of articles coherent in citation relationships. This study suggests eight fast growing recent themes. They span widely encompassing politics, romantic relationships, public relations, journalism, and health. Among them, four focus their issues largely on Twitter, three on Facebook, and one generally on both. While discussions on traditional issues in SNSs such as personality, motivations, self-disclosure, narcissism, etc. continue to lead the pack, the proliferation of the highlighted recent themes in the near future is very likely to happen.

  6. Identifying acne treatment uncertainties via a James Lind Alliance Priority Setting Partnership

    OpenAIRE

    Layton, Alison; Eady, E Anne; Peat, Maggie; Whitehouse, Heather; Levell, Nick; Ridd, Matthew; Cowdell, Fiona; Patel, Mahendra; Andrews, Stephen; Oxnard, Christine; Fenton, Mark; Firkins, Lester

    2015-01-01

    Objectives: The Acne Priority Setting Partnership\\ud (PSP) was set up to identify and rank treatment\\ud uncertainties by bringing together people with acne,\\ud and professionals providing care within and beyond the\\ud National Health Service (NHS).\\ud Setting: The UK with international participation.\\ud Participants: Teenagers and adults with acne,\\ud parents, partners, nurses, clinicians, pharmacists,\\ud private practitioners.\\ud Methods: Treatment uncertainties were collected via\\ud separat...

  7. NETWORK SERVICES FOR DIAGNOSTIC OPTODIGITAL COMPLEX FOR TELEMEDICINE

    OpenAIRE

    D. S. Kopylov; S. N. Ustinov; A. A. Skshidlevsky; A. V. Lyamin

    2014-01-01

    The paper deals with a result of the network services development for the optodigital complex for telemedicine diagnostics. This complex is designed for laboratory and clinical tests in health care facilities. Composition of network services includes the following: a client application for database of diagnostic test, a web-service, a web interface, a video server and microimage processing server. Structure of these services makes it possible to combine set of software for transferring depers...

  8. Utility communication networks and services specification, deployment and operation

    CERN Document Server

    2017-01-01

    This CIGRE green book begins by addressing the specification and provision of communication services in the context of operational applications for electrical power utilities, before subsequently providing guidelines on the deployment or transformation of networks to deliver these specific communication services. Lastly, it demonstrates how these networks and their services can be monitored, operated, and maintained to ensure that the requisite high level of service quality is consistently achieved.

  9. The Role of Social Networking Services in eParticipation

    DEFF Research Database (Denmark)

    Sæbø, Øystein; Rose, Jeremy; Nyvang, Tom

    2009-01-01

    investigates the potential of Social Networking Services for the eParticipation area by defining social networking services, introducing the driving forces behind their advance, and discusses the potential use of social networking software in the eParticipation context....... and social networking because democratic systems favour the interests of larger groups of citizens --- the more voices behind a political proposition, the greater its chances of success. In this context of challenges the study of social networking on the internet and social network theory offers valuable...... insights into the practices and theories of citizen engagement. Social network theory focuses on the chains of relationships that social actors communicate and act within. Some social networking services on the internet attract large numbers of users, and apparently sustain a great deal of interaction...

  10. Natural Acne Treatment: What's Most Effective?

    Science.gov (United States)

    ... What's most effective? Are there any effective natural acne treatment options? Answers from Brent A. Bauer, M.D. ... mayoclinic.org/diseases-conditions/acne/expert-answers/natural-acne-treatment/FAQ-20057915 . Mayo Clinic Footer Legal Conditions and ...

  11. Network performance and fault analytics for LTE wireless service providers

    CERN Document Server

    Kakadia, Deepak; Gilgur, Alexander

    2017-01-01

     This book is intended to describe how to leverage emerging technologies big data analytics and SDN, to address challenges specific to LTE and IP network performance and fault management data in order to more efficiently manage and operate an LTE wireless networks. The proposed integrated solutions permit the LTE network service provider to operate entire integrated network, from RAN to Core , from UE to application service, as one unified system and correspondingly collect and align disparate key metrics and data, using an integrated and holistic approach to network analysis. The LTE wireless network performance and fault involves the network performance and management of network elements in EUTRAN, EPC and IP transport components, not only as individual components, but also as nuances of inter-working of these components. The key metrics for EUTRAN include radio access network accessibility, retainability, integrity, availability and mobility. The key metrics for EPC include MME accessibility, mobility and...

  12. Service Demand Discovery Mechanism for Mobile Social Networks.

    Science.gov (United States)

    Wu, Dapeng; Yan, Junjie; Wang, Honggang; Wang, Ruyan

    2016-11-23

    In the last few years, the service demand for wireless data over mobile networks has continually been soaring at a rapid pace. Thereinto, in Mobile Social Networks (MSNs), users can discover adjacent users for establishing temporary local connection and thus sharing already downloaded contents with each other to offload the service demand. Due to the partitioned topology, intermittent connection and social feature in such a network, the service demand discovery is challenging. In particular, the service demand discovery is exploited to identify the best relay user through the service registration, service selection and service activation. In order to maximize the utilization of limited network resources, a hybrid service demand discovery architecture, such as a Virtual Dictionary User (VDU) is proposed in this paper. Based on the historical data of movement, users can discover their relationships with others. Subsequently, according to the users activity, VDU is selected to facilitate the service registration procedure. Further, the service information outside of a home community can be obtained through the Global Active User (GAU) to support the service selection. To provide the Quality of Service (QoS), the Service Providing User (SPU) is chosen among multiple candidates. Numerical results show that, when compared with other classical service algorithms, the proposed scheme can improve the successful service demand discovery ratio by 25% under reduced overheads.

  13. On Managed Services Lanes and their Use in Home Networks

    NARCIS (Netherlands)

    Hartog, F.T.H. den; Nooren, P.A.; Delphinanto, A.; Fledderus, E.R

    2013-01-01

    Home networks show an increasing level of heterogeneity regarding the devices connected, network technologies used, and services supported. Heterogeneity inhibits quality assurance for new services, such as online gaming, energy management, and health care. This paper focuses on the role that the

  14. Service and transfer selection for freights in a synchromodal network

    NARCIS (Netherlands)

    Perez Rivera, Arturo Eduardo; Mes, Martijn R.K.

    2016-01-01

    We study the planning problem of selecting services and transfers in a synchromodal network to transport freights with diff erent characteristics, over a multi-period horizon. The evolution of the network over time is determined by the decisions made, the schedule of the services, and the new

  15. Service and transfer selection for freights in a synchromodal network

    NARCIS (Netherlands)

    Perez Rivera, Arturo Eduardo; Mes, Martijn R.K.; Paias, Ana; Ruthmair, Mario; Voß, Stefan

    2016-01-01

    We study the problem of selecting services and transfers in a synchromodal network to transport freights with different characteristics, over a multi-period horizon. The evolution of the network over time is determined by the decisions made, the schedule of the services, and the new freights that

  16. Network as a service for next generation internet

    CERN Document Server

    Duan, Qiang

    2017-01-01

    This book presents the state of the art of the Network-as-a-Service (NaaS) paradigm, including its concepts, architecture, key technologies, applications, and development directions for future network service provisioning. It provides a comprehensive reference that reflects the most current technical developments related to NaaS.

  17. Transformation of legacy network management system to service oriented architecture

    Science.gov (United States)

    Sathyan, Jithesh; Shenoy, Krishnananda

    2007-09-01

    Service providers today are facing the challenge of operating and maintaining multiple networks, based on multiple technologies. Network Management System (NMS) solutions are being used to manage these networks. However the NMS is tightly coupled with Element or the Core network components. Hence there are multiple NMS solutions for heterogeneous networks. Current network management solutions are targeted at a variety of independent networks. The wide spread popularity of IP Multimedia Subsystem (IMS) is a clear indication that all of these independent networks will be integrated into a single IP-based infrastructure referred to as Next Generation Networks (NGN) in the near future. The services, network architectures and traffic pattern in NGN will dramatically differ from the current networks. The heterogeneity and complexity in NGN including concepts like Fixed Mobile Convergence will bring a number of challenges to network management. The high degree of complexity accompanying the network element technology necessitates network management systems (NMS) which can utilize this technology to provide more service interfaces while hiding the inherent complexity. As operators begin to add new networks and expand existing networks to support new technologies and products, the necessity of scalable, flexible and functionally rich NMS systems arises. Another important factor influencing NMS architecture is mergers and acquisitions among the key vendors. Ease of integration is a key impediment in the traditional hierarchical NMS architecture. These requirements trigger the need for an architectural framework that will address the NGNM (Next Generation Network Management) issues seamlessly. This paper presents a unique perspective of bringing service orientated architecture (SOA) to legacy network management systems (NMS). It advocates a staged approach in transforming a legacy NMS to SOA. The architecture at each stage is detailed along with the technical advantages and

  18. Does diet really affect acne?

    Science.gov (United States)

    Ferdowsian, H R; Levin, S

    2010-03-01

    Acne vulgaris has anecdotally been attributed to diet by individuals affected by this skin condition. In a 2009 systematic literature review of 21 observational studies and 6 clinical trials, the association between acne and diet was evaluated. Observational studies, including 2 large controlled prospective trials, reported that cow's milk intake increased acne prevalence and severity. Furthermore, prospective studies, including randomized controlled trials, demonstrated a positive association between a high-glycemic-load diet, hormonal mediators, and acne risk. Based on these findings, there exists convincing data supporting the role of dairy products and high-glycemic-index foods in influencing hormonal and inflammatory factors, which can increase acne prevalence and severity. Studies have been inconclusive regarding the association between acne and other foods.

  19. [Acne vulgaris. Role of cosmetics].

    Science.gov (United States)

    Korting, H C; Borelli, C; Schöllmann, C

    2010-02-01

    Appropriate cosmetics for skin cleansing are capable of contributing to a reduction of especially inflammatory lesions in acne-prone patients and to support pharmacological intervention in patients with manifest acne. Cleansing of acne-prone skin should employ acidified synthetic cleansers with a pH of 5.5 rather than soap. Furthermore, the ingredients of certain skin care products, i.e. nicotinamide, lactic acid, triethyl acetate/ethyllineolate, and prebiotic plant extracts, affect different mechanisms of acne pathogenesis and therefore may contribute to a decrease in acne lesions. At least some of these ingredients underscore the concept of evidence-based cosmetics. In contrast, the problem of acne lesions caused by comedogenic ingredients in cosmetics today is negligible.

  20. [Acne and rosacea in pregnancy].

    Science.gov (United States)

    Bechstein, S K; Ochsendorf, F

    2017-02-01

    Acne and rosacea are common chronic inflammatory skin diseases. During pregnancy these skin disorders may become aggravated, in rare cases occurring for the first time. There are no data available for rosacea and little data for acne concerning the course of these skin disorders during pregnancy. Up to 42% of the pregnant women suffer from acne. In 90% of these women the disease existed before pregnancy. In 1/3, however, acne relapsed during pregnancy after a prior disease-free period. In 60% acne deteriorated during pregnancy. Randomized controlled trials for the treatment of acne or rosacea during pregnancy do not exist. In this article the recommendations of current guidelines are modified, so that effective treatments can be recommended without harming the embryo or fetus.

  1. Dietary intervention in acne

    Science.gov (United States)

    Melnik, Bodo

    2012-01-01

    The purpose of this paper is to highlight the endocrine signaling of Western diet, a fundamental environmental factor involved in the pathogenesis of epidemic acne. Western nutrition is characterized by high calorie uptake, high glycemic load, high fat and meat intake, as well as increased consumption of insulin- and IGF-1-level elevating dairy proteins. Metabolic signals of Western diet are sensed by the nutrient-sensitive kinase, mammalian target of rapamycin complex 1 (mTORC1), which integrates signals of cellular energy, growth factors (insulin, IGF-1) and protein-derived signals, predominantly leucine, provided in high amounts by milk proteins and meat. mTORC1 activates SREBP, the master transcription factor of lipogenesis. Leucine stimulates mTORC1-SREBP signaling and leucine is directly converted by sebocytes into fatty acids and sterols for sebaceous lipid synthesis. Over-activated mTORC1 increases androgen hormone secretion and most likely amplifies androgen-driven mTORC1 signaling of sebaceous follicles. Testosterone directly activates mTORC1. Future research should investigate the effects of isotretinoin on sebocyte mTORC1 activity. It is conceivable that isotretinoin may downregulate mTORC1 in sebocytes by upregulation of nuclear levels of FoxO1. The role of Western diet in acne can only be fully appreciated when all stimulatory inputs for maximal mTORC1 activation, i.e., glucose, insulin, IGF-1 and leucine, are adequately considered. Epidemic acne has to be recognized as an mTORC1-driven disease of civilization like obesity, type 2 diabetes, cancer and neurodegenerative diseases. These new insights into Western diet-mediated mTORC1-hyperactivity provide a rational basis for dietary intervention in acne by attenuating mTORC1 signaling by reducing (1) total energy intake, (2) hyperglycemic carbohydrates, (3) insulinotropic dairy proteins and (4) leucine-rich meat and dairy proteins. The necessary dietary changes are opposed to the evolution of

  2. Propionibacterium acnes induces autophagy in keratinocytes: involvement of multiple mechanisms.

    Science.gov (United States)

    Megyeri, Klára; Orosz, László; Bolla, Szilvia; Erdei, Lilla; Rázga, Zsolt; Seprényi, György; Urbán, Edit; Szabó, Kornélia; Kemény, Lajos

    2017-11-27

    Propionibacterium acnes is a dominant member of the cutaneous microbiota. Herein, we evaluate the effects of different P. acnes strains and propionic acid on autophagy in keratinocytes. Our results showed that P. acnes strain 889 altered the architecture of the mitochondrial network, elevated the levels of LC3B-II, Beclin-1 and phospho-AMPKα, stimulated autophagic flux, facilitated intracellular redistribution of LC3B, increased average number of autophagosomes per cell, and enhanced development of acidic vesicular organelles in the HPV-KER cell line. Propionic acid increased the level of phospho-AMPKα, enhanced lipidation of LC3B, stimulated autophagic flux, as well as facilitated translocation of LC3B into autophagosomes in HPV-KER cells. P. acnes strains 889, 6609 and heat-killed strain 889 also stimulated autophagosome formation in primary keratinocytes to varying degrees. These results indicate that cell wall components and secreted propionic acid metabolite of P. acnes evoke mitochondrial damage successively, thereby trigger AMPK-associated activation of autophagy, which in turn facilitates the removal of dysfunctional mitochondria and promotes survival of keratinocytes. Thus, we suggest that low-level colonization of hair follicles with non-invasive P. acnes strains, by triggering a local increase in autophagic activity, might exert a profound effect on several physiological processes responsible for the maintenance of skin tissue homeostasis. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  3. Quantitative analysis of access strategies to remoteinformation in network services

    DEFF Research Database (Denmark)

    Olsen, Rasmus Løvenstein; Schwefel, Hans-Peter; Hansen, Martin Bøgsted

    2006-01-01

    Remote access to dynamically changing information elements is a required functionality for various network services, including routing and instances of context-sensitive networking. Three fundamentally different strategies for such access are investigated in this paper: (1) a reactive approach in......, network delay characterization) and specific requirements on mismatch probability, traffic overhead, and access delay. Finally, the analysis is applied to the use-case of context-sensitive service discovery....

  4. Improving User Experience of Internet Services in Cellular Networks

    OpenAIRE

    Klockar, Annika

    2015-01-01

    The Internet has grown enormously since the introduction of the World Wide Web in the early 90's. The evolution and wide spread deployment of cellular networks have contributed to make the Internet accessible to more people in more places. The cellular networks of today offer data rates high enough for most Internet services. Even so, the service quality experienced by the users is often lower than in wired networks. The performance of TCP has a large impact on user experience. Therefore, we ...

  5. Advanced techniques for multicast service provision in core transport networks

    OpenAIRE

    Fernández del Carpio, Gonzalo

    2012-01-01

    Although the network-based multicast service is the optimal way to support of a large variety of popular applications such as high-definition television (HDTV), videoon- demand (VoD), virtual private LAN service (VPLS), grid computing, optical storage area networks (O-SAN), video conferencing, e-learning, massive multiplayer online role-playing games (MMORPG), networked virtual reality, etc., there are a number of technological and operational reasons that prevents a wider deployment. This Ph...

  6. Exoenzymes of Propionibacterium acnes.

    Science.gov (United States)

    Kabongo Muamba, M L

    1982-07-01

    Thirty strains of Propionibacterium acnes were grown in basal salt medium containing lecithin as a lipid substrate and in other media. The cultures were assayed for production of lipase (measured as fatty acid esterase) and other exoenzymes. Lipase was assayed spectrophotometrically; other enzymes were assayed using the API ZYM system (Analytab Products Inc., Plainview, NY). Substance for lipase were alpha- and beta-naphthol esters of propionic, butyric, valeric, caprylic, lauric, myristic, and oleic acids. All strains showed fatty acid esterase activity. Using the API ZYM system 19 enzymes were detected, 8 of which were found frequently and had high activity in most strains. Acid and alkaline phosphatases, phosphoamidase, ester lipase, trypsin-chymotrypsin-like proteases, beta-glucuronidase (80%), beta-galactosidase (80%), and N-acetyl-beta-glucosaminidase were found. Many enzymes of P. acnes appear to be adaptive, dependent on the culture substrate.

  7. [Acne therapy in pregnancy].

    Science.gov (United States)

    Bayerl, C

    2013-04-01

    Acne should be treated during pregnancy to prevent worsening, scarring, secondary infection or psychological impairment of the mother. Safe products must be chosen. Systemic tetracycline, doxycycline, minocycline or isotretinoin can not be used. Topical benzoyl peroxide or topical azelaic acid are safe therapeutic options. According to the guidelines, systemic corticosteroids or systemic erythromycin (the latter not in lactation) can be employed beginning in the second trimester for severe flares of acne and should be started in cooperation with the patient's gynecologist. Oral zinc is another option, but not for longer than 3 months. Accessory cosmetic measures may be useful, including mechanical peeling or chemical peeling with glycolic or alpha-hydroxy-acids. In contrast, salicylic acid, trichloracetic acid or phenol peels should not be performed in pregnancy. Camouflage makeup can clearly lower the psychological stress.

  8. Treating acne vulgaris.

    Science.gov (United States)

    Mysliborski, J A; Lumpkin, L R

    1977-02-01

    While there is no single treatment plan that will work for every patient, acne can be controlled and long-term scarring can be minimized. Treatment must be individualized. Remember, there may be a "flare" when intensive therapy begins. Useful treatment methods include ultraviolet light, cleansers and soaps, peeling and drying agents, benzoyl peroxide preparations, abrasive soaps and scrubs, retinoic acid and oral antibiotics. The therapeutic choice depends upon the extent and severity of the disease.

  9. Dietary intervention in acne

    OpenAIRE

    Melnik, Bodo

    2012-01-01

    The purpose of this paper is to highlight the endocrine signaling of Western diet, a fundamental environmental factor involved in the pathogenesis of epidemic acne. Western nutrition is characterized by high calorie uptake, high glycemic load, high fat and meat intake, as well as increased consumption of insulin- and IGF-1-level elevating dairy proteins. Metabolic signals of Western diet are sensed by the nutrient-sensitive kinase, mammalian target of rapamycin complex 1 (mTORC1), which integ...

  10. [Acne and diet].

    Science.gov (United States)

    Melnik, B C

    2013-04-01

    In industrialized countries acne presents as an epidemic disease of civilization affecting sebaceous follicles of adolescents and young adults, associated with increased body mass index and insulin resistance. "Western style" diet, characterized by high glycaemic load and increased consumption of insulinotropic milk proteins, plays an important role in acne pathogenesis. On the cellular level, nutrient-derived metabolic signals are sensed by the metabolic transcription factor FoxO1 and integrated by the regulatory kinase mTORC1. mTORC1, the central hub of protein- and lipid biosynthesis, cell growth and proliferation, is activated by insulin, IGF-1 and branched-chain essential amino acids, especially leucine. The understanding of Western diet-mediated nutrient signalling with over-activated mTORC1 offers a reasonable approach for dietary intervention in acne by lowering glycaemic load and consumption of milk and milk products. A suitable diet attenuating increased mTORC1 activity is a Palaeolithic-like diet with reduced intake of sugar, hyperglycaemic grains, milk and milk products but enriched consumption of vegetables and fish.

  11. Prevalence of acne in primary school children and the relationship of acne with pubertal maturation

    Directory of Open Access Journals (Sweden)

    Hilal Kaya Erdoğan

    2014-12-01

    Full Text Available Background and Design: Although acne vulgaris is generally regarded as a disease of adolescence period, it can occur in infancy, early childhood and prepubertal period. Acne may emerge as the first sign of pubertal maturation. In our study, we aimed to determine the acne prevalence in primary school children, then, evaluate the pubertal signs in those children; examine the correlation of the presence and severity of acne with pubertal signs, and finally, revise the concept of prepubertal acne. Materials and Methods: A thousand students from 2 schools in Istanbul were included in the study. Age, gender, and the presence, localization and severity of acne were recorded. Acne severity was evaluated using the Orfanos-Gollnick Acne Grading System while a validated self evaluation form which had been developed by Morris and Udry was used to evaluate pubertal stage. Data were evaluated statistically. Results: Five hundred and thirty-four male and 466 female primary school children, with an age range of 7 to 11, were included in the study. Acne was determined in 11.5% of the students. 20% of girls and 4% of boys had acne. Comparing acne presence and age, the average age was higher in group with acne than those with no acne. The mean age of children with grade 1 acne was lower than those with grade 2 acne. All the students with acne had mid-facial acne. Comparing acne presence and pubertal symptoms, the rate of the presence of acne was higher in pubertal girls. No acne was observed in prepubertal boys. Evaluating acne severity and pubertal signs, the difference between prepubertal and pubertal girls was not significant. Comparing acne and telarche stages, the group without acne had lower telarche rates. Comparing acne and pubertal stages, children with acne had advanced puberty. Conclusion: Our study denotes that acne prevalence is related to pubertal maturation and age; while it does not support the hypothesis that acne is the first sign of pubertal

  12. Application of Network Analysis for Characterizing Service Modularity

    DEFF Research Database (Denmark)

    Frandsen, Thomas

    2012-01-01

    The purpose of this paper is to explore the potential of the application of network analytical techniques to identify and characterize modularity of service processes. Services can be conceptualized as systems of interrelated components which can be decomposed in order to achieve a modular design....... The paper is based on a network theory perspective to the quantification and visualization of service process architectures. Metrics are considered in order to evaluate their usefulness for academics and practitioners interested in understanding service system design. The paper suggests a number of metrics...... of importance for evaluating components and their interrelationships in service systems....

  13. Cluster-based service discovery for heterogeneous wireless sensor networks

    NARCIS (Netherlands)

    Marin Perianu, Raluca; Scholten, Johan; Havinga, Paul J.M.; Hartel, Pieter H.

    We propose an energy-efficient service discovery protocol for heterogeneous wireless sensor networks that interact with the users in open and dynamic environments. Our solution exploits a cluster overlay, where the clusterhead nodes form a distributed service registry. A service lookup results in

  14. Cluster-based service discovery for heterogeneous wireless sensor networks

    NARCIS (Netherlands)

    Marin Perianu, Raluca; Scholten, Johan; Havinga, Paul J.M.; Hartel, Pieter H.

    2007-01-01

    We propose an energy-efficient service discovery protocol for heterogeneous wireless sensor networks. Our solution exploits a cluster overlay, where the clusterhead nodes form a distributed service registry. A service lookup results in visiting only the clusterhead nodes. We aim for minimizing the

  15. Structure of Retail Services in the Brazilian Hosting Network

    Directory of Open Access Journals (Sweden)

    Claudio Zancan

    2015-08-01

    Full Text Available this research has identified Brazilian hosting networks through infrastructure services indicators that it was sold to tourists in organizations that form these networks. The theory consulted the discussion of structural techniques present in Social Network Analysis. The study has three stages: documental research, creation of Tourism database and interviews. The results identified three networks with the highest expression in Brazil formed by hotels, lodges, and resorts. Different char-acteristics of infrastructure and services were observed between hosting networks. Future studies suggest a comparative analysis of structural indicators present in other segments of tourism services, as well as the existing international influ-ence on the development of the Brazilian hosting networks.

  16. The Role of Social Networking Services in eParticipation

    Science.gov (United States)

    Sæbø, Øystein; Rose, Jeremy; Nyvang, Tom

    A serious problem in eParticipation projects is citizen engagement - citizens do not necessarily become more willing to participate simply because net-services are provided for them. Most forms of eParticipation in democratic contexts are, however, dependent on citizen engagement, interaction and social networking because democratic systems favour the interests of larger groups of citizens - the more voices behind a political proposition, the greater its chances of success. In this context of challenges the study of social networking on the internet and social network theory offers valuable insights into the practices and theories of citizen engagement. Social network theory focuses on the chains of relationships that social actors communicate and act within. Some social networking services on the internet attract large numbers of users, and apparently sustain a great deal of interaction, content-generation and the development of loosely-coupled communities. They provide the forum for much discussion and interaction. In this respect social networking could contribute to solve some of the problems of engaging their users that eParticipation services often struggle with. This paper investigates the potential of Social Networking Services for the eParticipation area by defining social networking services, introducing the driving forces behind their advance, and discusses the potential use of social networking software in the eParticipation context.

  17. Correlation between Propionibacterium acnes biotypes, lipase activity and rash degree in acne patients.

    Science.gov (United States)

    Higaki, S; Kitagawa, T; Kagoura, M; Morohashi, M; Yamagishi, T

    2000-08-01

    We examined the possible correlation between biotypes of Propionibacterium acnes, lipase activity, and rash degree in acne patients. Among 5 P. acnes biotypes, P. acnes biotype 3 (B3) was the most common, followed by P. acnes biotypes 1, 2 and 4; P. acnes biotype 5 was not found. P. acnes B3 was isolated from more severe skin rashes than those of the other biotypes. Production of propionic acid (PA) and butyric acid (BA) by P. acnes B3 was higher than those by the other P. acnes biotypes. As the rash degree in acne patients was more severe, the production of PA and BA elevated. Although only a few P. acnes strains were examined in the present study, P. acnes B3 had the highest lipase activity and might have the greatest influence on skin rash in acne patients.

  18. Technology Licensing Strategy for Network Product in a Service Industry

    Directory of Open Access Journals (Sweden)

    Xianpei Hong

    2015-01-01

    Full Text Available Technology licensing has gained significant attention in literature and practice as a rapid and effective way to improve firm’s capability of technology innovation. In this paper, we investigate a duopolistic service provider competition market, where service providers develop and sell a kind of network product. In this setting, we analyze the innovating service provider’s four licensing strategies: no licensing, fixed fee licensing, royalty licensing, and two-part tariff licensing. The literature suggests that when the network products can be completely substituted, two-part tariff licensing is the optimal strategy of the innovating service provider. We find that when the network products cannot be completely substituted, two-part tariff licensing is not always optimal. The degree of the product differentiation, the intensity of the network effects, and the R&D cost of the potential licensee play a key role in determining the innovating service provider’s optimal licensing strategies.

  19. Service network design of bike sharing systems analysis and optimization

    CERN Document Server

    Vogel, Patrick

    2016-01-01

    This monograph presents a tactical planning approach for service network design in metropolitan areas. Designing the service network requires the suitable aggregation of demand data as well as the anticipation of operational relocation decisions. To this end, an integrated approach of data analysis and mathematical optimization is introduced. The book also includes a case study based on real-world data to demonstrate the benefit of the proposed service network design approach. The target audience comprises primarily research experts in the field of traffic engineering, but the book may also be beneficial for graduate students.

  20. Servitization in China via an External Service Partner Network

    DEFF Research Database (Denmark)

    Raja, Jawwad; Frandsen, Thomas

    2016-01-01

    Previous research has predominately focused on the servitization strategies of Western manufacturers in advanced economies, neglecting the potential in those which are emerging, such as China. This paper explores the role of the external service partner network of a European manufacturer providing...... services in China in order to develop a better understanding of the challenges. An in-depth multiple case study approach was taken to examine the parent company, its subsidiary in China and the related service partner network. Data collection involved all three actors and took place in Denmark and China....... The findings suggest that motivation, opportunity and ability (MOA) need not only be mutually reinforcing for the organization attempting to move towards services but also congruent within the external service partner network. Furthermore, the findings suggest that an external service partner may not be able...

  1. Quebec mental health services networks: models and implementation

    Directory of Open Access Journals (Sweden)

    Marie-Josée Fleury

    2005-06-01

    Full Text Available Purpose: In the transformation of health care systems, the introduction of integrated service networks is considered to be one of the main solutions for enhancing efficiency. In the last few years, a wealth of literature has emerged on the topic of services integration. However, the question of how integrated service networks should be modelled to suit different implementation contexts has barely been touched. To fill that gap, this article presents four models for the organization of mental health integrated networks. Data sources: The proposed models are drawn from three recently published studies on mental health integrated services in the province of Quebec (Canada with the author as principal investigator. Description: Following an explanation of the concept of integrated service network and a description of the Quebec context for mental health networks, the models, applicable in all settings: rural, urban or semi-urban, and metropolitan, and summarized in four figures, are presented. Discussion and conclusion: To apply the models successfully, the necessity of rallying all the actors of a system, from the strategic, tactical and operational levels, according to the type of integration involved: functional/administrative, clinical and physician-system is highlighted. The importance of formalizing activities among organizations and actors in a network and reinforcing the governing mechanisms at the local level is also underlined. Finally, a number of integration strategies and key conditions of success to operationalize integrated service networks are suggested.

  2. Is acne caused by colonization with the "wrong" strain of Propionibacterium acnes? A review of the role of Propionibacterium acnes in acne

    DEFF Research Database (Denmark)

    Lomholt, Hans Bredsted; Kilian, Mogens

    2008-01-01

    Acne is still a major problem, and treatment options are far from ideal. A number of studies suggest that the species Propionibacterium acnes plays an important role in the pathogenesis, and new data point towards molecular mechanisms by which the organism is able to trigger the host inflammatory...... response. The current knowledge on P. acnes in relation to acne is reviewed....

  3. Service Knowledge Discovery in Smart Machine Networks

    NARCIS (Netherlands)

    Durmus, Y.; Onur, E.

    2015-01-01

    The devices surrounding us become smarter and can autonomously form a network without requiring our intervention. However, our needs can be even better accommodated when the networked devices cooperate and complement each other’s capabilities. One of the initial steps towards achieving a cooperative

  4. DEVELOPMENT OF HERBAL ANTI ACNE GEL AND ITS EVALUATION AGAINST ACNE CAUSING BACTERIA PROPIONIBACTERIUM ACNE AND STAPHYLOCOCCUS EPIDERMIDIS

    OpenAIRE

    Daud Farhat S.; Wankhede Shubhangi; Joshi Mamta; Pande Gauri

    2013-01-01

    Acne by definition is multifactorial chronic inflammatory disease of pilosebaceous units. Propionibacterium acnes and Staphylococcus epidermidis are considered as the major skin bacteria that cause the formation of acne. Although acne does not pose serious threat to general health, it is one of the most socially distressing conditions especially for adolescents. The objective of this study was to design a product to treat Acne with purely herbal actives as an effective and safe alternative to...

  5. 78 FR 41088 - Solicitation for a Cooperative Agreement-Support Services for Community Services Division Networks

    Science.gov (United States)

    2013-07-09

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF JUSTICE... Services Division Networks AGENCY: National Institute of Corrections, U.S., Department of Justice. ACTION... for the network participants, prepare a detailed report for the network manager, create a quarterly...

  6. Acne vulgaris: pathogenesis, treatment, and needs assessment.

    Science.gov (United States)

    Knutsen-Larson, Siri; Dawson, Annelise L; Dunnick, Cory A; Dellavalle, Robert P

    2012-01-01

    Acne vulgaris is a common skin condition with substantial cutaneous and psychologic disease burden. Studies suggest that the emotional impact of acne is comparable to that experienced by patients with systemic diseases, like diabetes and epilepsy. In conjunction with the considerable personal burden experienced by patients with acne, acne vulgaris also accounts for substantial societal and health care burden. The pathogenesis and existing treatment strategies for acne are complex. This article discusses the epidemiology, pathogenesis, and treatment of acne vulgaris. The burden of disease in the United States and future directions in the management of acne are also addressed. Copyright © 2012 Elsevier Inc. All rights reserved.

  7. Free space optical networks for ultra-broad band services

    CERN Document Server

    Kartalopoulos, Stamatios V

    2011-01-01

    "Free Space Optical Network is a next generation communication network which uses optical waves instead of microwaves, potentially offering faster communication with ultra band width, meaning more complex communication services can be simultaneously offered. This book describes the network concepts in simple language starting with point-to-point free space optics basics and discusses networking, interoperability with existing communication network, and security. An ideal resource for communication professionals just entering the free space optical communication field and graduate students majoring in optical communications"--Provided by publisher.

  8. Mobile location services over the next generation IP core network

    DEFF Research Database (Denmark)

    Thongthammachart, Saowanee; Olesen, Henning

    2003-01-01

    network is changing from circuit-switched to packet-switched technology and evolving to an IP core network based on IPv6. The IP core network will allow all IP devices to be connected seamlessly. Due to the movement detection mechanism of Mobile IPv6, mobile terminals will periodically update....... The concept of mobile location services over the next generation IP networks is described. We also discuss the effectiveness of the short-range wireless network regarding a mobile user's position inside buildings and hotspot areas....

  9. Hybrid services efficient provisioning over the network coding-enabled elastic optical networks

    Science.gov (United States)

    Wang, Xin; Gu, Rentao; Ji, Yuefeng; Kavehrad, Mohsen

    2017-03-01

    As a variety of services have emerged, hybrid services have become more common in real optical networks. Although the elastic spectrum resource optimizations over the elastic optical networks (EONs) have been widely investigated, little research has been carried out on the hybrid services of the routing and spectrum allocation (RSA), especially over the network coding-enabled EON. We investigated the RSA for the unicast service and network coding-based multicast service over the network coding-enabled EON with the constraints of time delay and transmission distance. To address this issue, a mathematical model was built to minimize the total spectrum consumption for the hybrid services over the network coding-enabled EON under the constraints of time delay and transmission distance. The model guarantees different routing constraints for different types of services. The immediate nodes over the network coding-enabled EON are assumed to be capable of encoding the flows for different kinds of information. We proposed an efficient heuristic algorithm of the network coding-based adaptive routing and layered graph-based spectrum allocation algorithm (NCAR-LGSA). From the simulation results, NCAR-LGSA shows highly efficient performances in terms of the spectrum resources utilization under different network scenarios compared with the benchmark algorithms.

  10. An extended differentiated optical services model for WDM optical networks

    Science.gov (United States)

    Ouyang, Yong; Zeng, Qingji; Wei, Wei

    2004-04-01

    The need to provide QoS-guaranteed services in the WDM optical networks is becoming increasingly important because of a variety of candidate client networks (e.g., IP, ATM, SONET/SDH) and the requirement for QoS-delivery within the transport layers. This article addresses the QoS problem and presents a framework of QoS provisioning in the WDM optical network. We first characterize the QoS problem in the WDM optical network by comparing with that in the traditional networks. Then we propose a QoS service model in the optical domain called extended differentiated optical services (E-DoS) model based on a set of optical parameters that captures the quality, the reliability and the priority of an optical connection. Each component of the E-DoS model has been analyzed in detail in this article.

  11. Decentralized Fault Management for Service Dependability in Ubiquitous Networks

    DEFF Research Database (Denmark)

    Grønbæk, Lars Jesper

    2010-01-01

    simulation model. Some of the main findings are: i) certain imperfection trade-off settings of the Diagnosis component lead to worse end-user service reliability than if no fault management is conducted, ii) using end-user service state information in the decision process can help improve service reliability......Obtaining reliable operation of end-user services in future ubiquitous networking environments is challenging. Faults occur and heterogeneous networks make it difficult to deploy network wide fault management mechanisms. This PhD lecture presents a study on the options an end-node has to mitigate......) unobservable and incomplete network state information, ii) unreliable observations, and iii) dynamic environments calling for adaptation in the fault management process. In the study, focus is on potential gains in the interaction between the components of Observation, Diagnosis, Decision and Remediation...

  12. RESTful Web services in Wireless Sensor Networks

    OpenAIRE

    Moreno Yeste, Pol

    2011-01-01

    Premi Accenture al millor projecte de fi de carrera d’Enginyeria de Telecomunicació en Serveis Telemàtics (curs 2011-2012) English: Wireless Sensor Networks (WSNs) have become very popular in recent years. A WSN consists of distributed autonomous sensors to monitor physical or environmental conditions and to cooperatively send their data through the network to a main location. A WSN facilitates the creation of low-cost networks that can be used for multiple applications when the use of wir...

  13. Towards Secure and Privacy-Preserving Online Social Networking Services

    OpenAIRE

    Gong, Zhenqiang

    2015-01-01

    Online social networking services (e.g., Facebook, Twitter, and Blogger) bring new benefits to almost all aspects of our lives. They have completely transformed how we communicate with each other, how we process information, and how we diffuse social influence. However, these social networking services are also plagued by both conventional and emerging threats to security and privacy. For instance, two fundamental security risks are 1) users’ accounts are compromised by attackers or get lost ...

  14. Towards Psychometrics-based Friend Recommendations in Social Networking Services

    OpenAIRE

    Beierle, Felix; Grunert, Kai; Göndör, Sebastian; Schlüter, Viktor

    2017-01-01

    Two of the defining elements of Social Networking Services are the social profile, containing information about the user, and the social graph, containing information about the connections between users. Social Networking Services are used to connect to known people as well as to discover new contacts. Current friend recommendation mechanisms typically utilize the social graph. In this paper, we argue that psychometrics, the field of measuring personality traits, can help make meaningful frie...

  15. Acne Scars: Pathogenesis, Classification and Treatment

    OpenAIRE

    Fabbrocini, Gabriella; Annunziata, M. C.; D'Arco, V.; De Vita, V.; Lodi, G.; Mauriello, M. C.; Pastore, F.; Monfrecola, G.

    2010-01-01

    Acne has a prevalence of over 90% among adolescents and persists into adulthood in approximately 12%–14% of cases with psychological and social implications. Possible outcomes of the inflammatory acne lesions are acne scars which, although they can be treated in a number of ways, may have a negative psychological impact on social life and relationships. The main types of acne scars are atrophic and hypertrophic scars. The pathogenesis of acne scarring is still not fully understood, but seve...

  16. Distributed Service Discovery for Heterogeneous Wireless Sensor Networks

    NARCIS (Netherlands)

    Marin Perianu, Raluca; Scholten, Johan; Havinga, Paul J.M.

    Service discovery in heterogeneous Wireless Sensor Networks is a challenging research objective, due to the inherent limitations of sensor nodes and their extensive and dense deployment. The protocols proposed for ad hoc networks are too heavy for sensor environments. This paper presents a

  17. Evolution of the Converged NGN Service Platforms Towards Future Networks

    NARCIS (Netherlands)

    Mikóczy, E.; Kotuliak, I.; Deventer, M.O. van

    2011-01-01

    This article presents a comparison of main characteristics of the Next Generation Networks (NGN) and Future Generation Internet (FGI). The aim is to discuss and compare two approaches to Future Networks (FN) and services: the evolution of NGN, and the revolutionary approach of a new FGI. We present

  18. Efficient health care service delivery using network analysis: a case ...

    African Journals Online (AJOL)

    Efficient health care service delivery using network analysis: a case study of Kwara State, Nigeria. ... Ethiopian Journal of Environmental Studies and Management ... This paper addresses challenges with prompt health care delivery using Network Analysis of Critical Path Model (CPM) to plan the hospital capacity with a ...

  19. Certificate Based Security Services in Adhoc Sensor Network

    OpenAIRE

    Shahin Fatima; Shish Ahmad; P. M. Khan

    2014-01-01

    The paper entitled “CERTIFICATE BASED SECURITY SERVICES IN ADHOC SENSOR NETWORK” proposed an approach in which the aim is to find the method for authentication which is more energy efficient and reduces the transmission time of the network. MANETs are of dynamic topology and have no predefined infrastructure. Due to its dynamic topology this network is prone to various kinds of vulnerable attacks. Sensor networks are battery operated and is a major concern. Methods on ID based Authentication ...

  20. Security management of next generation telecommunications networks and services

    CERN Document Server

    Jacobs, Stuart

    2014-01-01

    This book will cover network management security issues and currently available security mechanisms by discussing how network architectures have evolved into the contemporary NGNs which support converged services (voice, video, TV, interactive information exchange, and classic data communications). It will also analyze existing security standards and their applicability to securing network management. This book will review 21st century security concepts of authentication, authorization, confidentiality, integrity, nonrepudiation, vulnerabilities, threats, risks, and effective approaches to enc

  1. One network metric datastore to track them all: the OSG network metric service

    Science.gov (United States)

    Quick, Robert; Babik, Marian; Fajardo, Edgar M.; Gross, Kyle; Hayashi, Soichi; Krenz, Marina; Lee, Thomas; McKee, Shawn; Pipes, Christopher; Teige, Scott

    2017-10-01

    The Open Science Grid (OSG) relies upon the network as a critical part of the distributed infrastructures it enables. In 2012, OSG added a new focus area in networking with a goal of becoming the primary source of network information for its members and collaborators. This includes gathering, organizing, and providing network metrics to guarantee effective network usage and prompt detection and resolution of any network issues, including connection failures, congestion, and traffic routing. In September of 2015, this service was deployed into the OSG production environment. We will report on the creation, implementation, testing, and deployment of the OSG Networking Service. Starting from organizing the deployment of perfSONAR toolkits within OSG and its partners, to the challenges of orchestrating regular testing between sites, to reliably gathering the resulting network metrics and making them available for users, virtual organizations, and higher level services, all aspects of implementation will be reviewed. In particular, several higher-level services were developed to bring the OSG network service to its full potential. These include a web-based mesh configuration system, which allows central scheduling and management of all the network tests performed by the instances; a set of probes to continually gather metrics from the remote instances and publish it to different sources; a central network datastore (esmond), which provides interfaces to access the network monitoring information in close to real time and historically (up to a year) giving the state of the tests; and a perfSONAR infrastructure monitor system, ensuring the current perfSONAR instances are correctly configured and operating as intended. We will also describe the challenges we encountered in ongoing operations of the network service and how we have evolved our procedures to address those challenges. Finally we will describe our plans for future extensions and improvements to the service.

  2. Acne Vulgaris and Acne Rosacea: An Update in Etiopathogenesis

    Directory of Open Access Journals (Sweden)

    Ozlem Ekiz

    2014-04-01

    Full Text Available Acne vulgaris is a chronic inflammatory disease of the pilosebaceous unit, characterized by comedones, papules, pustules, nodules, and scars rarely. The major pathogenic factors are abnormal follicular differentiation and increased ductal cornification, abnormal activity of sebaceous glands, microbial colonization of pilosebaceous units by Propionibacterium acnes and inflammation. Rosacea is a common, chronic inflammatory relapsing skin disorder of the central area of the face characterized by transient or persistent erythema, telangiectasia, papules and pustules. Although several hypotheses have been suggested for the etiopathogenesis of rosacea, the exact etiology is still unknown. In this review, we tried to summarize up-to-date information about etiopathogenesis of acne vulgaris and rosocea.

  3. A case of acne fulminans

    Directory of Open Access Journals (Sweden)

    Mihai A. Badea

    2017-04-01

    Full Text Available Background and aim: Acne fulminans is a rare and severe form of acne which usually appears in young men with a personal history of mild to moderate acne. It is characterized by a sudden onset with nodules and ulcerative lesions mostly located on the thorax and extracutaneous manifestations (fever, weight loss, osteoarticular damage. The pathophysiologic mechanism is represented by a type III or IV hypersensitivity reaction to Propionibacterium acnes. Patient: We present the case of a 16-year old patient with acne fulminans. The lesions were accompanied by an impaired general condition with fever and weight loss. Paraclinically an inflammatory syndrome was revealed without osteoarticular changes. It was treated with prednisone 40 mg/day, erythromycin 2g/day and local antiseptic solutions. A gradual tapering of the prednisone dose (5 mg/week and a dermatological revaluation after 3 weeks to introduce systemic treatment with retinoids were recommended at discharge. Conclusions: Acne fulminans is a severe form of acne with systemic manifestations and corticotherapy is the first line treatment.

  4. A framework for automated service composition in collaborative networks

    NARCIS (Netherlands)

    Afsarmanesh, H.; Sargolzaei, M.; Shadi, M.

    2012-01-01

    This paper proposes a novel framework for automated software service composition that can significantly support and enhance collaboration among enterprises in service provision industry, such as in tourism insurance and e-commerce collaborative networks (CNs). Our proposed framework is founded on

  5. Prototyping Service Discovery and Usage in Wireless Sensor Networks

    NARCIS (Netherlands)

    Marin Perianu, Raluca; Scholten, Johan; Havinga, Paul J.M.

    2007-01-01

    Heterogeneous Wireless Sensor Networks (WSNs) are envisioned to provide different types of services in an open and dynamic environment. This paper presents the design, implementation and evaluation of a service discovery and usage solution for heterogeneous WSNs. The users have the possibility to

  6. A Service-Oriented Approach for Dynamic Chaining of Virtual Network Functions over Multi-Provider Software-Defined Networks

    Directory of Open Access Journals (Sweden)

    Barbara Martini

    2016-06-01

    Full Text Available Emerging technologies such as Software-Defined Networks (SDN and Network Function Virtualization (NFV promise to address cost reduction and flexibility in network operation while enabling innovative network service delivery models. However, operational network service delivery solutions still need to be developed that actually exploit these technologies, especially at the multi-provider level. Indeed, the implementation of network functions as software running over a virtualized infrastructure and provisioned on a service basis let one envisage an ecosystem of network services that are dynamically and flexibly assembled by orchestrating Virtual Network Functions even across different provider domains, thereby coping with changeable user and service requirements and context conditions. In this paper we propose an approach that adopts Service-Oriented Architecture (SOA technology-agnostic architectural guidelines in the design of a solution for orchestrating and dynamically chaining Virtual Network Functions. We discuss how SOA, NFV, and SDN may complement each other in realizing dynamic network function chaining through service composition specification, service selection, service delivery, and placement tasks. Then, we describe the architecture of a SOA-inspired NFV orchestrator, which leverages SDN-based network control capabilities to address an effective delivery of elastic chains of Virtual Network Functions. Preliminary results of prototype implementation and testing activities are also presented. The benefits for Network Service Providers are also described that derive from the adaptive network service provisioning in a multi-provider environment through the orchestration of computing and networking services to provide end users with an enhanced service experience.

  7. User Identification Framework in Social Network Services Environment

    Directory of Open Access Journals (Sweden)

    Brijesh BAKARIYA

    2014-01-01

    Full Text Available Social Network Service is a one of the service where people may communicate with one an-other; and may also exchange messages even of any type of audio or video communication. Social Network Service as name suggests a type of network. Such type of web application plays a dominant role in internet technology. In such type of online community, people may share their common interest. Facebook LinkedIn, orkut and many more are the Social Network Service and it is good medium of making link with people having unique or common interest and goals. But the problem of privacy protection is a big issue in today’s world. As social networking sites allows anonymous users to share information of other stuffs. Due to which cybercrime is also increasing to a rapid extent. In this article we preprocessed the web log data of Social Network Services and assemble that data on the basis of image file format like jpg, jpeg, gif, png, bmp etc. and also propose a framework for victim’s identification.

  8. Acne conglobata and Klinefelter's syndrome.

    Science.gov (United States)

    Wollenberg, A; Wolff, H; Jansen, T; Schmid, M H; Röcken, M; Plewig, G

    1997-03-01

    Acne conglobata has been reported to be more common and more severe in XYY chromosomal aberration than in normal subjects. Whereas only exceptional cases have been observed in the more common XXY Klinefelter karyotype. We report a 17-year-old male with both Klinefelter's syndrome and acne conglobata, spreading from face to upper arms, trunk, buttocks and upper legs. The serum level of testosterone was normal, whereas luteinizing hormone and follicle-stimulating hormone were elevated. Skin lesions responded well to a combined therapeutic regimen including oral isotretinoin and prednisolone. An overview of severe acne in relation to chromosomal abnormalities is given and diagnostic and therapeutic options discussed.

  9. An Optimal Routing Algorithm in Service Customized 5G Networks

    Directory of Open Access Journals (Sweden)

    Haipeng Yao

    2016-01-01

    Full Text Available With the widespread use of Internet, the scale of mobile data traffic grows explosively, which makes 5G networks in cellular networks become a growing concern. Recently, the ideas related to future network, for example, Software Defined Networking (SDN, Content-Centric Networking (CCN, and Big Data, have drawn more and more attention. In this paper, we propose a service-customized 5G network architecture by introducing the ideas of separation between control plane and data plane, in-network caching, and Big Data processing and analysis to resolve the problems traditional cellular radio networks face. Moreover, we design an optimal routing algorithm for this architecture, which can minimize average response hops in the network. Simulation results reveal that, by introducing the cache, the network performance can be obviously improved in different network conditions compared to the scenario without a cache. In addition, we explore the change of cache hit rate and average response hops under different cache replacement policies, cache sizes, content popularity, and network topologies, respectively.

  10. Structural Quality of Service in Large-Scale Networks

    DEFF Research Database (Denmark)

    Pedersen, Jens Myrup

    , telephony and data. To meet the requirements of the different applications, and to handle the increased vulnerability to failures, the ability to design robust networks providing good Quality of Service is crucial. However, most planning of large-scale networks today is ad-hoc based, leading to highly......Digitalization has created the base for co-existence and convergence in communications, leading to an increasing use of multi service networks. This is for example seen in the Fiber To The Home implementations, where a single fiber is used for virtually all means of communication, including TV...... complex networks lacking predictability and global structural properties. The thesis applies the concept of Structural Quality of Service to formulate desirable global properties, and it shows how regular graph structures can be used to obtain such properties....

  11. Awareness of LGBT aging issues among aging services network providers.

    Science.gov (United States)

    Hughes, Anne K; Harold, Rena D; Boyer, Janet M

    2011-10-01

    Very little research exists examining the interactions between community-based aging service providers and lesbian, gay, bisexual, and transgender (LGBT) older adults. It is unclear whether mainstream aging services acknowledge the needs of this community. We asked direct care providers and administrators in the Michigan aging services network to describe their work with LGBT older adults. We found there are very few services specific to the needs of older LGBT adults and very little outreach to this community. At the agency level, resistance to providing services was found.

  12. SDN-based QoS Aware Network Service Provisioning

    DEFF Research Database (Denmark)

    Caba, Cosmin Marius; Soler, José

    2015-01-01

    One of the applicability areas of SDN is for creating services for dynamic provisioning of network resources with strict QoS requirements. The research available in this field focuses mainly on the service logic implemented over the functionality of the SDN Controller (SDNC). However, there is much....... More specifically, the paper will look into on demand provisioning of Virtual Circuits (VCs) with specific QoS, based on the SDN paradigm. The aim is to analyze and compare the strategies for network resources management for two cases: a coarse granular and a fine granular VC provisioning service...

  13. Interventions for acne scars.

    Science.gov (United States)

    Abdel Hay, Rania; Shalaby, Khalid; Zaher, Hesham; Hafez, Vanessa; Chi, Ching-Chi; Dimitri, Sandra; Nabhan, Ashraf F; Layton, Alison M

    2016-04-03

    Acne scarring is a frequent complication of acne and resulting scars may negatively impact on an affected person's psychosocial and physical well-being. Although a wide range of interventions have been proposed, there is a lack of high-quality evidence on treatments for acne scars to better inform patients and their healthcare providers about the most effective and safe methods of managing this condition. This review aimed to examine treatments for atrophic and hypertrophic acne scars, but we have concentrated on facial atrophic scarring. To assess the effects of interventions for treating acne scars. We searched the following databases up to November 2015: the Cochrane Skin Group Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL) in the Cochrane Library (2015, Issue 10), MEDLINE (from 1946), EMBASE (from 1974), and LILACS (from 1982). We also searched five trials registers, and checked the reference lists of included studies and relevant reviews for further references to randomised controlled trials. We include randomised controlled trials (RCTs) which allocated participants (whether split-face or parallel arms) to any active intervention (or a combination) for treating acne scars. We excluded studies dealing only or mostly with keloid scars. Three review authors independently extracted data from each of the studies included in this review and evaluated the risks of bias. We resolved disagreements by discussion and arbitration supported by a method expert as required. Our primary outcomes were participant-reported scar improvement and any adverse effects serious enough to cause participants to withdraw from the study. We included 24 trials with 789 adult participants aged 18 years or older. Twenty trials enrolled men and women, three trials enrolled only women and one trial enrolled only men. We judged eight studies to be at low risk of bias for both sequence generation and allocation concealment. With regard to blinding we judged

  14. The psychosocial impact of acne vulgaris

    Directory of Open Access Journals (Sweden)

    Neirita Hazarika

    2016-01-01

    Full Text Available Background: Acne vulgaris causes erythematous papulopustular lesions in active stage and often leave behind residual scarring and pigmentation. Its onset in adolescence may add to the emotional and psychological challenges experienced during this period. Aims: To assess the impact of acne on the various psychosocial domains of daily life. Materials and Methods: This was a prospective, cross-sectional study done in the dermatology out-patient department of a tertiary care hospital from January to March 2015. A total of 100 consecutive, newly diagnosed patients of acne vulgaris, aged 15 years and above were included in this study. The relationship between acne vulgaris and its sequelae was analyzed with ten different domains of daily life by using dermatology life quality index (DLQI questionnaire. Results: Females (56%, 15–20 year olds (61%, facial lesions (60%, and Grade II acne (70% were most common. Acne scars were noted in 75% patients, whereas 79% cases had post-acne hyperpigmentation. Thirty-seven percent patients had DLQI scores of (6–10 interpreted as moderate effect on patient's life. Statistically significant correlation (P < 0.05 found were as follows: Physical symptoms with grade of acne; embarrassment with site and grade of acne; daily activities with grade of acne and post-acne pigmentation; choice of clothes with site of acne; social activities with gender, site and grade of acne; effect on work/study with grade of acne; interpersonal problems with site and post-acne pigmentation; sexual difficulties with grade of acne. Limitation: It was a hospital-based study with small sample size. Conclusion: Significant impact of acne and its sequelae was noted on emotions, daily activities, social activities, study/work, and interpersonal relationships. Assurance and counseling along with early treatment of acne vulgaris is important to reduce disease-related psychosocial sequelae and increase the efficacy of treatment.

  15. Hidradenitis Suppurativa/Acne Inversa

    DEFF Research Database (Denmark)

    Zouboulis, Christos C.; Del Marmol, Véronique; Mrowietz, Ulrich

    2015-01-01

    BACKGROUND: Hidradenitis suppurativa/acne inversa (HS) is a chronic, inflammatory, recurrent, debilitating disease, which inflicts a significant burden on patients and is associated with comorbid disorders, such as significantly reduced quality of life, depression, stigmatization, inactivity...

  16. NETWORK SERVICES FOR DIAGNOSTIC OPTODIGITAL COMPLEX FOR TELEMEDICINE

    Directory of Open Access Journals (Sweden)

    D. S. Kopylov

    2014-03-01

    Full Text Available The paper deals with a result of the network services development for the optodigital complex for telemedicine diagnostics. This complex is designed for laboratory and clinical tests in health care facilities. Composition of network services includes the following: a client application for database of diagnostic test, a web-service, a web interface, a video server and microimage processing server. Structure of these services makes it possible to combine set of software for transferring depersonalized medical data via the Internet and operating with optodigital devices included in the complex. Complex is consisted of three systems: micro-vision, endoscopic and network. The micro-vision system includes an automated digital microscope with two highly sensitive cameras which can be controlled remotely via the Internet. The endoscopic system gives the possibility to implement video broadcasting to remote users both during diagnostic tests and also off-line after tests. The network system is the core of the complex where network services and application software are functioning, intended for archiving, storage and providing access to the database of diagnostic tests. The following subjects are developed and tested for functional stability: states transfer protocol, commands transfer protocol and video-stream transfer protocol from automated digital microscope and video endoscope. These protocols can work in web browsers on modern mobile devices without additional software.

  17. [Analysing a public health service network's managerial competence].

    Science.gov (United States)

    Huerta-Riveros, Patricia C; Leyton-Pavez, Carolina E; Saldia-Barahona, Héctor

    2009-12-01

    Analysing the effectiveness of training-action methodology in developing and strengthening the skills required by public health network managerial staff. The study evaluated an educational programme (pre- and post- evaluation being applied within the programme's framework and conditions, without controlled conditions) in which 37 managerial staff from the Talcahuano Health Service Network (forming part of the Public Health Assistance Network) participated in the Managerial Team Training programme, 2007 and 2008, run by the Bío-Bío University's Entrepreneurial Science Faculty in Chile. A skill-based self-evaluation instrument was applied on two different occasions. The results revealed a lack of management skills-based training in network managerial teams and the need for it through training-action methodology which stimulates such needed managerial skills. Acquiring these skills will lead to providing users with a quality service through better management practice in public health establishments.

  18. Converged Wireless Networking and Optimization for Next Generation Services

    Directory of Open Access Journals (Sweden)

    J. Rodriguez

    2010-01-01

    Full Text Available The Next Generation Network (NGN vision is tending towards the convergence of internet and mobile services providing the impetus for new market opportunities in combining the appealing services of internet with the roaming capability of mobile networks. However, this convergence does not go far enough, and with the emergence of new coexistence scenarios, there is a clear need to evolve the current architecture to provide cost-effective end-to-end communication. The LOOP project, a EUREKA-CELTIC driven initiative, is one piece in the jigsaw by helping European industry to sustain a leading role in telecommunications and manufacturing of high-value products and machinery by delivering pioneering converged wireless networking solutions that can be successfully demonstrated. This paper provides an overview of the LOOP project and the key achievements that have been tunneled into first prototypes for showcasing next generation services for operators and process manufacturers.

  19. Acne vulgaris in children and adolescents.

    Science.gov (United States)

    Schnopp, C; Mempel, M

    2011-08-01

    Acne vulgaris is a very common inflammatory skin disease originating from the pilosebaceous unit. Peak incidence is at puberty, but acne can affect all age groups. Prepubertal acne is rare, but important to recognize as diagnostic and therapeutic procedures differ from pubertal acne. Acne neonatorum is a mild, self-limiting disease, whereas acne infantum commonly presents with moderate to severe lesions and high risk of scarring thus requiring early intervention. Mid-childhood or prepubertal acne raises the suspicion of hyperandrogenemia, further investigations are indicated to rule out underlying disease. The same applies to any patient with very severe acne, acne not responding to therapy or unusual clinical presentation. Etiopathogenesis of acne is not yet fully understood. Familiy history is the most important risk factor to develop severe acne and scarring. The relevance of life style factors such as smoking or diet is controversial. Lately high carbohydrate diet and dairy products have been implicated as aggravating factors. Mild acne normally responds to topical monotherapy, in moderate disease combination of two synergistically acting substances (e.g. benzoyl peroxid plus antibiotic, benzoyl peroxid plus retinoid, retinoid plus antibiotic, benzoyl peroxid plus azelaic acid) will improve clinical response. Retinoids and/or benzoylperoxid have been shown to be effective in maintenance therapy. In patients with severe disease or high risk of scarring systemic therapy with antibiotics, oral contraceptives with antiandrogenic properties and in particularly isotretinoin as most effective acne treatment should be considered early to avoid physical and emotional scars.

  20. Agent-based Personal Network (PN) service architecture

    DEFF Research Database (Denmark)

    Jiang, Bo; Olesen, Henning

    2004-01-01

    In this paper we proposte a new concept for a centralized agent system as the solution for the PN service architecture, which aims to efficiently control and manage the PN resources and enable the PN based services to run seamlessly over different networks and devices. The working principle......, control procedure and enabling techniques behind the agent based solution are the main focuses of this paper....

  1. Network Communication as a Service-Oriented Capability

    Energy Technology Data Exchange (ETDEWEB)

    Johnston, William; Johnston, William; Metzger, Joe; Collins, Michael; Burrescia, Joseph; Dart, Eli; Gagliardi, Jim; Guok, Chin; Oberman, Kevin; O' Conner, Mike

    2008-01-08

    In widely distributed systems generally, and in science-oriented Grids in particular, software, CPU time, storage, etc., are treated as"services" -- they can be allocated and used with service guarantees that allows them to be integrated into systems that perform complex tasks. Network communication is currently not a service -- it is provided, in general, as a"best effort" capability with no guarantees and only statistical predictability. In order for Grids (and most types of systems with widely distributed components) to be successful in performing the sustained, complex tasks of large-scale science -- e.g., the multi-disciplinary simulation of next generation climate modeling and management and analysis of the petabytes of data that will come from the next generation of scientific instrument (which is very soon for the LHC at CERN) -- networks must provide communication capability that is service-oriented: That is it must be configurable, schedulable, predictable, and reliable. In order to accomplish this, the research and education network community is undertaking a strategy that involves changes in network architecture to support multiple classes of service; development and deployment of service-oriented communication services, and; monitoring and reporting in a form that is directly useful to the application-oriented system so that it may adapt to communications failures. In this paper we describe ESnet's approach to each of these -- an approach that is part of an international community effort to have intra-distributed system communication be based on a service-oriented capability.

  2. Pregnancy Acne: What's the Best Treatment?

    Science.gov (United States)

    ... Accessed July 26, 2016. Pugashetti R, et al. Treatment of acne vulgaris in pregnancy patients. Dermatologic Therapy. 2013;26:302. Chien L, et al. Treatment of acne in pregnancy. Journal of the American Board of ...

  3. Natural Acne Treatment: What's Most Effective?

    Science.gov (United States)

    ... and young adults with mild to moderate acne. Aloe vera. A 50 percent aloe vera gel was combined with a conventional acne ... Elsevier; 2014. Hajheydari Z, et al. Effect of Aloe vera topical gel combined with tretinoin in treatment ...

  4. Acne, cystic on the face (image)

    Science.gov (United States)

    The face is the most common location of acne. Here, there are 4 to 6 millimeter red ( ... scars and fistulous tract formation (connecting passages). Severe acne may have a profound psychological impact and may ...

  5. Acne, vulgaris on the back (image)

    Science.gov (United States)

    Acne frequently occurs on the back. Here, there are 2 to 6 millimeter wide erythematous (red) pustules ... Permanent scarring may follow a severe case of acne. Men are more often affected on their shoulders ...

  6. Services in wireless sensor networks modelling and optimisation for the efficient discovery of services

    CERN Document Server

    Becker, Markus

    2014-01-01

    In recent years, originally static and single purpose Wireless Sensor Networks have moved towards applications that need support for mobility and multiple purposes. These heterogeneous applications and services demand for a framework which distributes and discovers the various services, so that other pieces of equipment can use them. Markus Becker studies, extends, analytically models, simulates and employs the so called Trickle algorithm in measurements in a Wireless Sensor Network test bed for the service distribution. The obtained results apply to the application of the Trickle algorithm at

  7. Assessing the State-of-the-Art in Dynamic Discovery of Ad Hoc Network Services

    Science.gov (United States)

    2001-07-18

    Cache Manager() 0..1 Contains 1 Contains SERVICE MANAGER discov er Network Context() <<not shr>> Cache Manager Discov ery () <<OPT>> Announce Serv ice...service availability requests Service Manager Service Cache Manager Service User Service Description Service Provider Service Repository Service...Group Service Manager Service User Service Cache Manager Aggressive Discovery Multicast Group SM4 SCM3 T ATT API GUI 20 30AddService50 SU8 5 1 2 S XYZ

  8. Current and future treatment options for acne.

    NARCIS (Netherlands)

    Kerkhof, P.C.M. van de; Kleinpenning, M.M.; Jong, E.M.G.J. de; Gerritsen, M.J.P.; Dooren-Greebe, R.J. van; Alkemade, J.A.C.

    2006-01-01

    Acne is a frequent skin disease with abnormalities in the process of keratinization, sebaceous gland functioning and inflammation. In this review, our understanding of the pathogenesis of acne has been updated. An overview of efficacy and side effects of available anti-acne treatments is presented.

  9. Quality of Service in Networks Supporting Cultural Multimedia Applications

    Science.gov (United States)

    Kanellopoulos, Dimitris N.

    2011-01-01

    Purpose: This paper aims to provide an overview of representative multimedia applications in the cultural heritage sector, as well as research results on quality of service (QoS) mechanisms in internet protocol (IP) networks that support such applications. Design/methodology/approach: The paper's approach is a literature review. Findings: Cultural…

  10. Vaccination targeting a surface sialidase of P. acnes: implication for new treatment of acne vulgaris.

    Directory of Open Access Journals (Sweden)

    Teruaki Nakatsuji

    Full Text Available BACKGROUND: Acne vulgaris afflicts more than fifty million people in the United State and the severity of this disorder is associated with the immune response to Propionibacterium acnes (P. acnes. Systemic therapies for acne target P. acnes using antibiotics, or target the follicle with retinoids such as isotretinoin. The latter systemic treatment is highly effective but also carries a risk of side effects including immune imbalance, hyperlipidemia, and teratogenicity. Despite substantial research into potential new therapies for this common disease, vaccines against acne vulgaris are not yet available. METHODS AND FINDINGS: Here we create an acne vaccine targeting a cell wall-anchored sialidase of P. acnes. The importance of sialidase to disease pathogenesis is shown by treatment of a human sebocyte cell line with recombinant sialidase that increased susceptibility to P. acnes cytotoxicity and adhesion. Mice immunized with sialidase elicit a detectable antibody; the anti-sialidase serum effectively neutralized the cytotoxicity of P. acnes in vitro and P. acnes-induced interleukin-8 (IL-8 production in human sebocytes. Furthermore, the sialidase-immunized mice provided protective immunity against P. acnes in vivo as this treatment blocked an increase in ear thickness and release of pro-inflammatory macrophage inflammatory protein (MIP-2 cytokine. CONCLUSIONS: Results indicated that acne vaccines open novel therapeutic avenues for acne vulgaris and other P. acnes-associated diseases.

  11. Network Management Services Based On The Openflow Environment

    Directory of Open Access Journals (Sweden)

    Paweł Wilk

    2014-01-01

    Full Text Available The subject of this article is network management through web service calls, which allows software applications to exert an influence on network traffic. In this manner, software can make independent decisions concerning the direction of requests so that they can be served as soon as possible. This is important because only proper cooperation including all architecture layers can ensure the best performance, especially when software that largely depends on computer networks and utilizes them heavily is involved. To demonstrate that the approach described above is feasible and can be useful at the same time, this article presents a switch-level load balancer developed using OpenFlow. Client software communicates with the balancer through REST web service calls, which are used to provide information on current machine load and its ability to serve incoming requests. The result is a cheap, highly customizable and extremely fast load balancer with considerable potential for further development.

  12. Asymmetric Competition in Network Services Provision in the Telecommunications Subsystems

    Directory of Open Access Journals (Sweden)

    Damir Šimulčik

    2012-10-01

    Full Text Available The majority of network services provision (postal and telecommunicationsservices, rail transport, air transport, etc.were traditionally considered as natural monopoly. New scenarioof the liberalised national market and "Open NetworkProvision" require precise and concrete economic evaluationbefore implementation itselfThis paper considers the methodology for the application ofnatural monopoly with the concept of cost sub-additivity. It ispointed out that the scale and scope economies, associatedwith "plant (network sub-additivity" is not sufficient to justifythe monopoly in every service provision in the traffic system andits subsystems. The paper considers and analyses the possiblemarket configuration with various degrees of competition fortelecommunication subsystem. The asymmetric competition inthe telecommunication subsystem by means of the dominantorganisation model has been analysed.

  13. Social networks and trade of services: modelling interregional flows with spatial and network autocorrelation effects

    Science.gov (United States)

    de la Mata, Tamara; Llano, Carlos

    2013-07-01

    Recent literature on border effect has fostered research on informal barriers to trade and the role played by network dependencies. In relation to social networks, it has been shown that intensity of trade in goods is positively correlated with migration flows between pairs of countries/regions. In this article, we investigate whether such a relation also holds for interregional trade of services. We also consider whether interregional trade flows in services linked with tourism exhibit spatial and/or social network dependence. Conventional empirical gravity models assume the magnitude of bilateral flows between regions is independent of flows to/from regions located nearby in space, or flows to/from regions related through social/cultural/ethic network connections. With this aim, we provide estimates from a set of gravity models showing evidence of statistically significant spatial and network (demographic) dependence in the bilateral flows of the trade of services considered. The analysis has been applied to the Spanish intra- and interregional monetary flows of services from the accommodation, restaurants and travel agencies for the period 2000-2009, using alternative datasets for the migration stocks and definitions of network effects.

  14. The epidemiology of acne vulgaris in late adolescence

    Directory of Open Access Journals (Sweden)

    Lynn DD

    2016-01-01

    Full Text Available Darren D Lynn,1 Tamara Umari,1 Cory A Dunnick,2,3 Robert P Dellavalle2–4 1Department of Dermatology, University of Colorado School of Medicine, 2Department of Dermatology, University of Colorado Anschutz Medical Campus, Aurora, 3Dermatology Service, US Department of Veterans Affairs, Eastern Colorado Health Care System, Denver, 4Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA Importance: Acne vulgaris is the most common skin condition affecting late adolescents across the globe. Although prior studies have evaluated epidemiologic patterns of acne vulgaris in various ethnicities and regions, adequate understanding of the worldwide burden of the disease associated with patients in their late adolescence (15–19-year olds remains lacking. Objective: To assess the global burden of the disease associated with acne vulgaris for late adolescents (15–19-year olds and provide an overview of the epidemiology, pathophysiology, and treatment options for acne in this population. Design: Database summary study. Setting: Global Burden of Disease Study 2010 database. Participants: Global Burden of Disease regions comprised countries with prevalence of acne vulgaris between the ages of 15 and 19 years. Main outcomes and measures: Geographic region-level disability-adjusted life year rates (per 100,000 persons associated with acne vulgaris in years 1990 through 2010. Median percentage change in disability-adjusted life year rates was estimated for each region across the specified study period. Conclusion and relevance: Acne vulgaris-associated disease burden exhibits global distribution and has continued to grow in prevalence over time within this population. This continued growth suggests an unmet dermatologic need worldwide for this disorder and potential opportunities for improved access and delivery of dermatologic care. Our analysis of the literature reveals numerous

  15. A neural network based reputation bootstrapping approach for service selection

    Science.gov (United States)

    Wu, Quanwang; Zhu, Qingsheng; Li, Peng

    2015-10-01

    With the concept of service-oriented computing becoming widely accepted in enterprise application integration, more and more computing resources are encapsulated as services and published online. Reputation mechanism has been studied to establish trust on prior unknown services. One of the limitations of current reputation mechanisms is that they cannot assess the reputation of newly deployed services as no record of their previous behaviours exists. Most of the current bootstrapping approaches merely assign default reputation values to newcomers. However, by this kind of methods, either newcomers or existing services will be favoured. In this paper, we present a novel reputation bootstrapping approach, where correlations between features and performance of existing services are learned through an artificial neural network (ANN) and they are then generalised to establish a tentative reputation when evaluating new and unknown services. Reputations of services published previously by the same provider are also incorporated for reputation bootstrapping if available. The proposed reputation bootstrapping approach is seamlessly embedded into an existing reputation model and implemented in the extended service-oriented architecture. Empirical studies of the proposed approach are shown at last.

  16. Fillers for the improvement in acne scars

    Directory of Open Access Journals (Sweden)

    Wollina U

    2015-09-01

    Full Text Available Uwe Wollina,1 Alberto Goldman2 1Department of Dermatology and Allergology, Academic Teaching Hospital, Dresden-Friedrichstadt, Dresden, Germany; 2Clinica Goldman, Porto Alegre, Rio Grande do Sul, Brazil Abstract: Acne is a common inflammatory disease. Scarring is an unwanted end point of acne. Both atrophic and hypertrophic scar types occur. Soft-tissue augmentation aims to improve atrophic scars. In this review, we will focus on the use of dermal fillers for acne scar improvement. Therefore, various filler types are characterized, and available data on their use in acne scar improvement are analyzed. Keywords: acne, scars, dermal fillers, injection, extracellular matrix

  17. A Survey on M2M Service Networks

    Directory of Open Access Journals (Sweden)

    Juhani Latvakoski

    2014-11-01

    Full Text Available The number of industrial applications relying on the Machine to Machine (M2M services exposed from physical world has been increasing in recent years. Such M2M services enable communication of devices with the core processes of companies. However, there is a big challenge related to complexity and to application-specific M2M systems called “vertical silos”. This paper focuses on reviewing the technologies of M2M service networks and discussing approaches from the perspectives of M2M information and services, M2M communication and M2M security. Finally, a discussion on technologies and approaches potentially enabling future autonomic M2M service networks are provided. According to our conclusions, it is seen that clear definition of the architectural principles is needed to solve the “vertical silo” problem and then, proceeding towards enabling autonomic capabilities for solving complexity problem appears feasible. Several areas of future research have been identified, e.g., autonomic information based services, optimization of communications with limited capability devices, real-time messaging, creation of trust and end to end security, adaptability, reliability, performance, interoperability, and maintenance.

  18. Moral learning in an integrated social and healthcare service network.

    Science.gov (United States)

    Visse, Merel; Widdershoven, Guy A M; Abma, Tineke A

    2012-09-01

    The traditional organizational boundaries between healthcare, social work, police and other non-profit organizations are fading and being replaced by new relational patterns among a variety of disciplines. Professionals work from their own history, role, values and relationships. It is often unclear who is responsible for what because this new network structure requires rules and procedures to be re-interpreted and re-negotiated. A new moral climate needs to be developed, particularly in the early stages of integrated services. Who should do what, with whom and why? Departing from a relational and hermeneutic perspective, this article shows that professionals in integrated service networks embark upon a moral learning process when starting to work together for the client's benefit. In this context, instrumental ways of thinking about responsibilities are actually counterproductive. Instead, professionals need to find out who they are in relation to other professionals, what core values they share and what responsibilities derive from these aspects. This article demonstrates moral learning by examining the case of an integrated social service network. The network's development and implementation were supported by responsive evaluation, enriched by insights of care ethics and hermeneutic ethics.

  19. Chemical Peels for Acne and Acne Scars in Asians: Evidence Based Review

    Science.gov (United States)

    Handog, Evangeline B; Datuin, Maria Suzanne L; Singzon, Ivan A

    2012-01-01

    Chemical peeling is a widely used procedure in the management of acne and acne scars, but there are very few studies on Asian populations who are more prone to develop hyper pigmentation. This article aims to summarize and evaluate the existing studies on the role of chemical peels in the treatment of acne and acne scars among Asians. An online search was conducted to identify prospective studies published in English that evaluated the use of chemical peels in active acne and acne scars in Asian populations. There were six studies for acne and eight studies for acne scars that were identified using our search parameters. Most were single-centre, open label and with small sample sizes. Acne severity was not uniformly reported and the objective outcome measures of some studies were not explicitly reported as well. The general trend of the results of the studies support the safety and efficacy of chemical peels for acne and acne scars including those of darker skin types. The existing studies support the use of chemical peels in the treatment of acne and acne scars in Asians. Further clinical trials with better study design and more subjects are needed to further establish the role of chemical peels in Asian acne patients. PMID:23378705

  20. Chemical peels for acne and acne scars in asians: Evidence based review

    Directory of Open Access Journals (Sweden)

    Evangeline B Handog

    2012-01-01

    Full Text Available Chemical peeling is a widely used procedure in the management of acne and acne scars, but there are very few studies on Asian populations who are more prone to develop hyper pigmentation. This article aims to summarize and evaluate the existing studies on the role of chemical peels in the treatment of acne and acne scars among Asians. An online search was conducted to identify prospective studies published in English that evaluated the use of chemical peels in active acne and acne scars in Asian populations. There were six studies for acne and eight studies for acne scars that were identified using our search parameters. Most were single-centre, open label and with small sample sizes. Acne severity was not uniformly reported and the objective outcome measures of some studies were not explicitly reported as well. The general trend of the results of the studies support the safety and efficacy of chemical peels for acne and acne scars including those of darker skin types. The existing studies support the use of chemical peels in the treatment of acne and acne scars in Asians. Further clinical trials with better study design and more subjects are needed to further establish the role of chemical peels in Asian acne patients.

  1. Correlated loss of ecosystem services in coupled mutualistic networks.

    Science.gov (United States)

    Albrecht, Jörg; Berens, Dana Gertrud; Jaroszewicz, Bogdan; Selva, Nuria; Brandl, Roland; Farwig, Nina

    2014-05-08

    Networks of species interactions promote biodiversity and provide important ecosystem services. These networks have traditionally been studied in isolation, but species are commonly involved in multiple, diverse types of interaction. Therefore, whether different types of species interaction networks coupled through shared species show idiosyncratic or correlated responses to habitat degradation is unresolved. Here we study the collective response of coupled mutualistic networks of plants and their pollinators and seed dispersers to the degradation of Europe's last relict of old-growth lowland forest (Białowieża, Poland). We show that logging of old-growth forests has correlated effects on the number of partners and interactions of plants in both mutualisms, and that these effects are mediated by shifts in plant densities on logged sites. These results suggest bottom-up-controlled effects of habitat degradation on plant-animal mutualistic networks, and predict that the conversion of primary old-growth forests to secondary habitats may cause a parallel loss of multiple animal-mediated ecosystem services.

  2. [Diet in pathogenesis of acne vulgaris].

    Science.gov (United States)

    Ozdarska, Katarzyna; Osucha, Karolina; Savitskyi, Stepan; Malejczyk, Jacek; Galus, Ryszard

    2017-10-23

    Acne vulgaris is one of the most common dermatologic condition especially among adolescents. Acne is related to excess sebum production by sebaceous glands, inflammation both within and adjacent to the comedones, hyperproliferation of Propionibacterium acnes. Some of investigations show association between acne and diet. Milk increases the level of IGF-1 leading to the synthesis of androgen-mediated increases sebum production. Chocolate predispose to hyperglycemia and insulinemia which aggravate of acne vulgaris. High levels of omega-6 fatty acids have been associated with increase of acne in contrast to omega-3 fatty acids, which decrease inflammation. Food have huge impact on development and severity of acne and may exert beneficial effect in the treatment of this disorder.

  3. Assessing Robustness Properties in Dynamic Discovery of Ad Hoc Network Services (Briefing Charts)

    Science.gov (United States)

    2001-10-04

    Task() start Aging Task() Serv ice Cache Manager() 0..1 Contains 1 Contains SERVICE MANAGER discov er Network Context() <<not shr>> Cache Manager...service availabilty requests 0..* 0..* service availability requests Service Manager Service Cache Manager Service User Service Description Service...Discovery Multicast Group Service Manager Service User Service Cache Manager Aggressive Discovery Multicast Group SM4 SCM3 T ATT API GUI 20

  4. Chemical Peels for Acne and Acne Scars in Asians: Evidence Based Review

    OpenAIRE

    Handog, Evangeline B; Datuin, Maria Suzanne L; Singzon, Ivan A

    2012-01-01

    Chemical peeling is a widely used procedure in the management of acne and acne scars, but there are very few studies on Asian populations who are more prone to develop hyper pigmentation. This article aims to summarize and evaluate the existing studies on the role of chemical peels in the treatment of acne and acne scars among Asians. An online search was conducted to identify prospective studies published in English that evaluated the use of chemical peels in active acne and acne scars in As...

  5. ADAPTIVE SERVICE PROVISIONING FOR MOBILE AD HOC NETWORKS

    Directory of Open Access Journals (Sweden)

    Cynthia Jayapal

    2010-09-01

    Full Text Available Providing efficient and scalable service provisioning in Mobile Ad Hoc Network (MANET is a big research challenge. In adaptive service provisioning mechanism an adaptive election procedure is used to select a coordinator node. The role of a service coordinator is crucial in any distributed directory based service provisioning scheme. The existing coordinator election schemes use either the nodeID or a hash function to choose the coordinator. In these schemes, the leader changes are more frequent due to node mobility. We propose an adaptive scheme that makes use of an eligibility factor that is calculated based on the distance to the zone center, remaining battery power and average speed to elect a core node that change according to the network dynamics. We also retain the node with the second highest priority as a backup node. Our algorithm is compared with the existing solution by simulation and the result shows that the core node selected by us is more stable and hence reduces the number of handoffs. This in turn improves the service delivery performance by increasing the packet delivery ratio and decreasing the delay, the overhead and the forwarding cost.

  6. Research on Holographic Evaluation of Service Quality in Power Data Network

    Science.gov (United States)

    Wei, Chen; Jing, Tao; Ji, Yutong

    2018-01-01

    With the rapid development of power data network, the continuous development of the Power data application service system, more and more service systems are being put into operation. Following this, the higher requirements for network quality and service quality are raised, in the actual process for the network operation and maintenance. This paper describes the electricity network and data network services status. A holographic assessment model was presented to achieve a comprehensive intelligence assessment on the power data network and quality of service in the operation and maintenance on the power data network. This evaluation method avoids the problems caused by traditional means which performs a single assessment of network performance quality. This intelligent Evaluation method can improve the efficiency of network operation and maintenance guarantee the quality of real-time service in the power data network..

  7. Enhanced security services for enabling pan-European healthcare networks.

    Science.gov (United States)

    Blobel, B; Pharow, P; Engel, K

    2001-01-01

    Establishing the Shared Care environment, communication and co-operation between healthcare establishments involved must be provided in a trustworthy way. This challenge is even more important for health networks using the Internet. In that context, services assuring both communication security and application security must be provided. Especially in the e-health environment, additionally to identity-related services certifying data or properties of principals, trustworthiness or authorisation for objects, components and functions must be established by Trusted Third Parties (TTP). Within the European Commission's Information Society Technologies (IST) Programme, the HARP project provides the "HARP Cross-Security Platform (HCSP)" needed in the open Web environment of pan-European networks. The solutions are under implementation and evaluation in the German ONCONET enabling a trustworthy framework for both health professionals and patients as well as supporting clinical studies.

  8. Monitoring Network and Service Availability with Open-Source Software

    Directory of Open Access Journals (Sweden)

    T. Michael Silver

    2010-03-01

    Full Text Available Silver describes the implementation of a monitoring system using an open-source software package to improve the availability of services and reduce the response time when troubles occur. He provides a brief overview of the literature available on monitoring library systems, and then describes the implementation of Nagios, an open-source network monitoring system, to monitor a regional library system’s servers and wide area network. Particular attention is paid to using the plug-in architecture to monitor library services effectively. The author includes example displays and configuration files.   Editor’s note: This article is the winner of the LITA/Ex Libris Writing Award, 2009.

  9. Enhancing Availability of Services Using Software-Defined Networking

    Directory of Open Access Journals (Sweden)

    Martin Klepac

    2015-01-01

    Full Text Available The immense growth of client requirements imposed on data centre and cloud providers results in a conflict with traditional networking concepts lacking the required agility. In order to promote flexibility, which data centre providers promise to their clients, this discrepancy needs to be resolved, for instance by employing the novel concept of Software-Defined Networking (SDN. This paper utilises this concept in order to minimise service downtime while performing live virtual machine migration. The work is aimed at small/medium-sized data centres and hence the findings are based on real communication patterns found in such environments. Results show that packet loss is slightly diminished while available throughput is increased thanks to the proactive approach taken during network topology changes when compared to the traditional approach based on L2 forwarding.

  10. Architectural transformations in network services and distributed systems

    CERN Document Server

    Luntovskyy, Andriy

    2017-01-01

    With the given work we decided to help not only the readers but ourselves, as the professionals who actively involved in the networking branch, with understanding the trends that have developed in recent two decades in distributed systems and networks. Important architecture transformations of distributed systems have been examined. The examples of new architectural solutions are discussed. Content Periodization of service development Energy efficiency Architectural transformations in Distributed Systems Clustering and Parallel Computing, performance models Cloud Computing, RAICs, Virtualization, SDN Smart Grid, Internet of Things, Fog Computing Mobile Communication from LTE to 5G, DIDO, SAT-based systems Data Security Guaranteeing Distributed Systems Target Groups Students in EE and IT of universities and (dual) technical high schools Graduated engineers as well as teaching staff About the Authors Andriy Luntovskyy provides classes on networks, mobile communication, software technology, distributed systems, ...

  11. The teenager with moderate acne

    African Journals Online (AJOL)

    Acne is an oft-encountered presentation in family practice, and while sometimes downplayed as essentially a "cosmetic" and self-limiting problem, it is nonetheless associated with a definite risk of scarring, both physically and emotionally. This paper uses the P-drug approach, as outlined in the WHO Guide to Good ...

  12. Service Oriented Architecture for Wireless Sensor Networks in Agriculture

    Science.gov (United States)

    Sawant, S. A.; Adinarayana, J.; Durbha, S. S.; Tripathy, A. K.; Sudharsan, D.

    2012-08-01

    Rapid advances in Wireless Sensor Network (WSN) for agricultural applications has provided a platform for better decision making for crop planning and management, particularly in precision agriculture aspects. Due to the ever-increasing spread of WSNs there is a need for standards, i.e. a set of specifications and encodings to bring multiple sensor networks on common platform. Distributed sensor systems when brought together can facilitate better decision making in agricultural domain. The Open Geospatial Consortium (OGC) through Sensor Web Enablement (SWE) provides guidelines for semantic and syntactic standardization of sensor networks. In this work two distributed sensing systems (Agrisens and FieldServer) were selected to implement OGC SWE standards through a Service Oriented Architecture (SOA) approach. Online interoperable data processing was developed through SWE components such as Sensor Model Language (SensorML) and Sensor Observation Service (SOS). An integrated web client was developed to visualize the sensor observations and measurements that enables the retrieval of crop water resources availability and requirements in a systematic manner for both the sensing devices. Further, the client has also the ability to operate in an interoperable manner with any other OGC standardized WSN systems. The study of WSN systems has shown that there is need to augment the operations / processing capabilities of SOS in order to understand about collected sensor data and implement the modelling services. Also, the very low cost availability of WSN systems in future, it is possible to implement the OGC standardized SWE framework for agricultural applications with open source software tools.

  13. Knowledge Creation Through Mobile Social Networks and Its Impact on Intentions to Use Innovative Mobile Services

    NARCIS (Netherlands)

    Kleijnen, M.H.P.; Lievens, A.; de Ruyter, K.; Wetzels, M.G.M.

    2009-01-01

    Taking a social network perspective, the authors investigate consumers' intentions to use innovative mobile services. With a sociometric survey, they empirically assess how consumers integrate and connect through mobile social networks, as well as how their network position influences knowledge

  14. Quality-of-Service differentiation in an integrated services GSM/GPRS network

    NARCIS (Netherlands)

    Litjens, R.; Boucherie, Richardus J.

    2001-01-01

    We develop and analyse a generic model for performance evaluation, parameter optimisation and dimensioning in a \\textsc{gsm}/\\textsc{gprs} network. The model enables analytical evaluation for a scenario of integrated speech, video and data services, potentially offered in distinct priority classes.

  15. Insulin resistance in severe acne vulgaris.

    Science.gov (United States)

    Emiroğlu, Nazan; Cengiz, Fatma Pelin; Kemeriz, Funda

    2015-08-01

    Acne vulgaris is a pilosebaceous gland disease that usually affects people from puberty to young adulthood. It is seen especially on the face, neck, trunk and arms. Its severity differs from patient to patient and its pathogenesis is multifactorial. The main pathogenic factors of acne are high sebaceous gland secretion, follicular hyperproliferation, high androgen effects, propionibacterium acnes colonization and inflammation. Diet is always thought a probable reason for acne and many studies are done about acne and diet. To determine the effect of insulin resistance in severe acne vulgaris. Two hundred and forty-three acne vulgaris patients and 156 healthy controls were enrolled into the study. The blood levels of insulin and glucose were measured. Homeostasis Model Assessment (HOMA) Index was calculated. The values were compared with the control group. All of the patients were in the severe acne group according to their scores on the global acne scoring scale. While fasting blood glucose levels were not different between the groups (p > 0.05, 82.91 ±9.76 vs. 80.26 ±8.33), the fasting insulin levels were significantly higher in the patient group than in the control group (p pathogenesis of acne.

  16. The Contribution of Social Networks to Individual Learning in Service Organizations

    Science.gov (United States)

    Poell, Rob F.; Van der Krogt, Ferd J.

    2007-01-01

    This study investigates how social networks in service organizations contribute to employee learning. Two specific types of social network seem especially relevant to individual learning: first, the service network, where employees carry out and improve their work, which may lead to learning; and second, the learning network, where employees…

  17. An SDN-based architecture for Network-as-a-Service

    NARCIS (Netherlands)

    Manthena, M.P.V. van; Adrichem, N.L.M.; Broek, C. van den; Kuipers, F.

    2015-01-01

    Network-as-a-Service (NaaS) is a cloud-based service model that offers on-demand network connectivity and the provisioning and management of network services. However, the actual orchestration of dynamically allocating underlying resources to customer requirements is not trivial. In this paper, we

  18. Understanding the Burden of Adult Female Acne

    Science.gov (United States)

    Kawata, Ariane K.; Daniels, Selena R.; Yeomans, Karen; Burk, Caroline T.; Callender, Valerie D.

    2014-01-01

    Objective: Typically regarded as an adolescent condition, acne among adult females is also prevalent. Limited data are available on the clinical characteristics and burden of adult female acne. The study objective was to describe clinical characteristics and psychosocial impact of acne in adult women. Design: Cross-sectional, web-based survey. Setting: Data were collected from a diverse sample of United States females. Participants: Women ages 25 to 45 years with facial acne (≥25 visible lesions). Measurements: Outcomes included sociodemographic and clinical characteristics, perceptions, coping behaviors, psychosocial impact of acne (health-related quality of life using acne-specific Quality of Life questionnaire and psychological status using Patient Health Questionnaire), and work/productivity. Results: A total of 208 women completed the survey (mean age 35±6 years), comprising White/Caucasian (51.4%), Black/African American (24.5%), Hispanic/Latino (11.1%), Asian (7.7%), and Other (5.3%). Facial acne presented most prominently on cheeks, chin, and forehead and was characterized by erythema, postinflammatory hyperpigmentation, and scarring. Average age of adult onset was 25±6 years, and one-third (33.7%) were diagnosed with acne as an adult. The majority (80.3%) had 25 to 49 visible facial lesions. Acne was perceived as troublesome and impacted self-confidence. Makeup was frequently used to conceal acne. Facial acne negatively affected health-related quality of life, was associated with mild/moderate symptoms of depression and/or anxiety, and impacted ability to concentrate on work or school. Conclusion: Results highlight the multifaceted impact of acne and provide evidence that adult female acne is under-recognized and burdensome. PMID:24578779

  19. Understanding the burden of adult female acne.

    Science.gov (United States)

    Tanghetti, Emil A; Kawata, Ariane K; Daniels, Selena R; Yeomans, Karen; Burk, Caroline T; Callender, Valerie D

    2014-02-01

    Typically regarded as an adolescent condition, acne among adult females is also prevalent. Limited data are available on the clinical characteristics and burden of adult female acne. The study objective was to describe clinical characteristics and psychosocial impact of acne in adult women. Cross-sectional, web-based survey. Data were collected from a diverse sample of United States females. Women ages 25 to 45 years with facial acne (≥25 visible lesions). Outcomes included sociodemographic and clinical characteristics, perceptions, coping behaviors, psychosocial impact of acne (health-related quality of life using acne-specific Quality of Life questionnaire and psychological status using Patient Health Questionnaire), and work/productivity. A total of 208 women completed the survey (mean age 35±6 years), comprising White/Caucasian (51.4%), Black/African American (24.5%), Hispanic/Latino (11.1%), Asian (7.7%), and Other (5.3%). Facial acne presented most prominently on cheeks, chin, and forehead and was characterized by erythema, postinflammatory hyperpigmentation, and scarring. Average age of adult onset was 25±6 years, and one-third (33.7%) were diagnosed with acne as an adult. The majority (80.3%) had 25 to 49 visible facial lesions. Acne was perceived as troublesome and impacted self-confidence. Makeup was frequently used to conceal acne. Facial acne negatively affected health-related quality of life, was associated with mild/moderate symptoms of depression and/or anxiety, and impacted ability to concentrate on work or school. RESULTS highlight the multifaceted impact of acne and provide evidence that adult female acne is under-recognized and burdensome.

  20. Mobile cloud networking: mobile network, compute, and storage as one service on-demand

    NARCIS (Netherlands)

    Jamakovic, Almerima; Bohnert, Thomas Michael; Karagiannis, Georgios; Galis, A.; Gavras, A.

    2013-01-01

    The Future Communication Architecture for Mobile Cloud Services: Mobile Cloud Networking (MCN)1 is a EU FP7 Large scale Integrating Project (IP) funded by the European Commission. MCN project was launched in November 2012 for the period of 36 month. In total top-tier 19 partners from industry and

  1. Acne fulminans successfully treated with prednisone and dapsone Acne fulminans tratada com prednisona associada à dapsona

    Directory of Open Access Journals (Sweden)

    Rafael Bandeira Lages

    2012-08-01

    Full Text Available Acne fulminans is a rare condition and the most severe form of acne. It involves the sudden onset of febrile and multisystemic symptoms, with poor response to ordinary therapy in patients who previously had mild to moderate acne. It is characterized by hemorrhagic ulcerative crusting lesions on the face, chest and upper back. The authors report a case of acne fulminans that was successfully treated with oral prednisone and dapsone.A acne fulminans é uma condição rara e a mais severa forma de acne. Manifesta-se com um quadro agudo, febril e multissistêmico, resistente à terapêutica convencional em doentes com antecedente de acne leve ou moderada. As lesões são caracteristicamente úlcero-hemorrágicas e acometem preferencialmente tórax e face. Os autores relatam um caso de acne fulminans com excelente resposta terapêutica ao tratamento empregado.

  2. SeaDataNet network services monitoring: Definition and Implementation of Service availability index

    Science.gov (United States)

    Lykiardopoulos, Angelos; Mpalopoulou, Stavroula; Vavilis, Panagiotis; Pantazi, Maria; Iona, Sissy

    2014-05-01

    SeaDataNet (SDN) is a standardized system for managing large and diverse data sets collected by the oceanographic fleets and the automatic observation systems. The SeaDataNet network is constituted of national oceanographic data centres of 35 countries, active in data collection. SeaDataNetII project's objective is to upgrade the present SeaDataNet infrastructure into an operationally robust and state-of-the-art infrastructure; therefore Network Monitoring is a step to this direction. The term Network Monitoring describes the use of system that constantly monitors a computer network for slow or failing components and that notifies the network administrator in case of outages. Network monitoring is crucial when implementing widely distributed systems over the Internet and in real-time systems as it detects malfunctions that may occur and notifies the system administrator who can immediately respond and correct the problem. In the framework of SeaDataNet II project a monitoring system was developed in order to monitor the SeaDataNet components. The core system is based on Nagios software. Some plug-ins were developed to support SeaDataNet modules. On the top of Nagios Engine a web portal was developed in order to give access to local administrators of SeaDataNet components, to view detailed logs of their own service(s). Currently the system monitors 35 SeaDataNet Download Managers, 9 SeaDataNet Services, 25 GeoSeas Download Managers and 23 UBSS Download Managers . Taking advantage of the continuous monitoring of SeaDataNet system components a total availability index will be implemented. The term availability can be defined as the ability of a functional unit to be in a state to perform a required function under given conditions at a given instant of time or over a given time interval, assuming that the required external resources are provided. Availability measures can be considered as a are very important benefit becauseT - The availability trends that can be

  3. New insights into acne pathogenesis: Exploring the role of acne-associated microbial populations

    OpenAIRE

    Bipul Kumar; Rajiv Pathak; P. Bertin Mary; Diksha Jha; Kabir Sardana; Hemant K. Gautam

    2016-01-01

    Acne vulgaris, a prevalent disorder of the skin, is found to increase the incidence of suicidal ideation in acne patients (∼7.1%). This creates a dilemma in the mind whether acne is a life threatening disease among humans. The main inducer for this multifactorial disease is microbial fluctuation of common resident microbes on the skin with each microbe possessing their own purpose and style in protecting the human body. For acne progression, the microbial population has to get around the defe...

  4. Papular Acne Scars of the Nose and Chin: An Under-recognised Variant of Acne Scarring

    OpenAIRE

    Ali, Faisal R; Michael Kirk; Vishal Madan

    2016-01-01

    Background: Scarring following acne vulgaris is common and can be of profound psychosocial consequence. Aims and Objectives: We have clinically noted a variant of acne scarring, overlooked by previous categorisation schemes, which we have denominated as papular acne scars of the nose and chin. We sought to characterise these novel entities further. Materials and Methods: Initially, we identified 14 patients with papular acne scars of the nose and chin in a cosmetic dermatology clinic, of whom...

  5. Acne Scars: Pathogenesis, Classification and Treatment

    Directory of Open Access Journals (Sweden)

    Gabriella Fabbrocini

    2010-01-01

    Full Text Available Acne has a prevalence of over 90% among adolescents and persists into adulthood in approximately 12%–14% of cases with psychological and social implications. Possible outcomes of the inflammatory acne lesions are acne scars which, although they can be treated in a number of ways, may have a negative psychological impact on social life and relationships. The main types of acne scars are atrophic and hypertrophic scars. The pathogenesis of acne scarring is still not fully understood, but several hypotheses have been proposed. There are numerous treatments: chemical peels, dermabrasion/microdermabrasion, laser treatment, punch techniques, dermal grafting, needling and combined therapies for atrophic scars: silicone gels, intralesional steroid therapy, cryotherapy, and surgery for hypertrophic and keloidal lesions. This paper summarizes acne scar pathogenesis, classification and treatment options.

  6. Oral contraceptives in the treatment of acne.

    Science.gov (United States)

    Tan, J K; Degreef, H

    2001-02-01

    Oral contraceptives (OCs) can reduce acne by lowering the production of adrenal and ovarian androgens, by inhibiting 5-alpha-reductase, which in turn, reduces the levels of dihydrotestosterone, and by stimulating sex hormone binding globulin (SHBG), thus reducing the levels of free testosterone. In newer OCs, such as Tricyclen and Diane-35, the progestin component is minimally androgenic and anti-androgenic respectively, thereby enhancing the favorable profile of these products in the treatment of hyperandrogenic disorders, including acne. The efficacy of these agents and their long-term safety profile supports their use in various grades of acne in females: * As adjunctive therapy to topical agents for women with mild non-scarring acne desiring oral contraception * As primary therapy for patients with moderate non-scarring acne in combination with topical therapy and systemic antibiotics * As one of two preferred methods of contraception in patients with scarring and severe inflammatory acne being treated with systemic isotretinoin.

  7. Evolution of the Converged NGN Service Platforms Towards Future Networks

    Directory of Open Access Journals (Sweden)

    Eugen Mikóczy

    2011-03-01

    Full Text Available This article presents a comparison of main characteristics of the Next Generation Networks (NGN and Future Generation Internet (FGI. The aim is to discuss and compare two approaches to Future Networks (FN and services: the evolution of NGN, and the revolutionary approach of a new FGI. We present both frameworks from the services point of view as they are delivered to the end-user, as well as from the architectural point of view. We compare selected properties of both approaches to explain commonalities and differences. Their challenges are similar: managing the quality of experience, mobility, security, scalability and providing openness to applications. Based on this comparison, we evaluate possible areas for future convergence in the approach of the two architectures to the Future Network concept. Our analysis shows that despite their different backgrounds, the internet’s FGI and telco’s NGN are not that different after all. The convergence of the two approaches therefore seems the only logical way forward.

  8. Synchronizing pharmacotherapy in acne with review of clinical care

    National Research Council Canada - National Science Library

    Ganjoo, Anil; Borade, Dhammraj; Sacchidanand, Sarvajnamurthy; Lahiri, Koushik; Godse, Kiran; Kharkar, Rajendra; Narayanan, Varsha; D'souza, Lyndon; Patwardhan, Narendra

    2017-01-01

    ... of Propionibacterium acnes, and inflammation. Several acne mono-treatment and combination treatment regimens are available and prescribed in the Indian market, ranging from retinoids, benzoyl peroxide (BPO...

  9. Comparative Genomics and Transcriptomics of Propionibacterium acnes

    OpenAIRE

    Brzuszkiewicz, Elzbieta; Weiner, January; Wollherr, Antje; Thürmer, Andrea; Hüpeden, Jennifer; Lomholt, Hans B.; Kilian, Mogens; Gottschalk, Gerhard; Daniel, Rolf; Mollenkopf, Hans-Joachim; Meyer, Thomas F.; Brüggemann, Holger

    2011-01-01

    The anaerobic Gram-positive bacterium Propionibacterium acnes is a human skin commensal that is occasionally associated with inflammatory diseases. Recent work has indicated that evolutionary distinct lineages of P. acnes play etiologic roles in disease while others are associated with maintenance of skin homeostasis. To shed light on the molecular basis for differential strain properties, we carried out genomic and transcriptomic analysis of distinct P. acnes strains. We sequenced ...

  10. Fillers for the improvement in acne scars

    OpenAIRE

    Wollina U; Goldman A

    2015-01-01

    Uwe Wollina,1 Alberto Goldman2 1Department of Dermatology and Allergology, Academic Teaching Hospital, Dresden-Friedrichstadt, Dresden, Germany; 2Clinica Goldman, Porto Alegre, Rio Grande do Sul, Brazil Abstract: Acne is a common inflammatory disease. Scarring is an unwanted end point of acne. Both atrophic and hypertrophic scar types occur. Soft-tissue augmentation aims to improve atrophic scars. In this review, we will focus on the use of dermal fillers for acne scar improvement. Therefore...

  11. Agriculture Information Service Built on Interoperable Sensor Network

    Science.gov (United States)

    Honda, K.; Ines, A.; Han, E.; Seshimo, T.

    2015-12-01

    We are developing an agricultural information service platform called FieldTouch, that is built on an interoperable geospatial data infrastructure. More than 300 farmers in Hokkaido, Japan, are participating on this development and they are utilizing our services for optimizing their daily agricultural practices. FieldTouch integrates multi-scale sensor data for field monitoring, provides functionality for recording agricultural practices, then supports farmers in decision making. The platform has two layers. The base layer is interoperable geospatial data infrastructure for sensor networks, that provides updated sensor data to upper application layer via OGC( Open Geospatial Consortium) standard API. We are updating RapidEye satellite images every two weeks, and field sensor data from 50 nodes. Agro-Weather data generated by NIAES using national weather observation network; AMeDAS is also a data source at daily basis. We use "cloudSense" sensor backend service as the infrastructure that serves meta-data and data to the application layer via standard web service; SOS (Sensor Observation Service). SOS provides unified procedure to applications when they access different type of sensor platform, which brought us a great flexibility and automation in operating the system. We developed a crop simulation application in FieldTouch so that farmers are able to see the impact of different planting data on yield. Cultivar data of local wheat variety for DSSAT crop model was calibrated by data assimilation. We generate 100 of weather scenario by a weather generator to present the obtain distribution of yield in different planting options. We update the weather scenario day by day in order to reduce the uncertain of the prediction towards harvesting. Visualizing expected yield as distributions help farmers to understand the risks by weather variability as well as to optimize their works and investment.

  12. Correlation between the Severity and Type of Acne Lesions with Serum Zinc Levels in Patients with Acne Vulgaris

    OpenAIRE

    Rostami Mogaddam, Majid; Safavi Ardabili, Nastaran; Maleki, Nasrollah; Soflaee, Maedeh

    2014-01-01

    Acne vulgaris is the most common cutaneous disorder affecting adolescents and young adults. Some studies have reported an association between serum zinc levels and acne vulgaris. We aimed to evaluate the serum zinc level in patients with acne vulgaris and compare it with healthy controls. One hundred patients with acne vulgaris and 100 healthy controls were referred to our clinic. Acne severity was classified according to Global Acne Grading System (GAGS). Atomic absorption spectrophotometry ...

  13. A Bloom Filter-Powered Technique Supporting Scalable Semantic Discovery in Data Service Networks

    Science.gov (United States)

    Zhang, J.; Shi, R.; Bao, Q.; Lee, T. J.; Ramachandran, R.

    2016-12-01

    More and more Earth data analytics software products are published onto the Internet as a service, in the format of either heavyweight WSDL service or lightweight RESTful API. Such reusable data analytics services form a data service network, which allows Earth scientists to compose (mashup) services into value-added ones. Therefore, it is important to have a technique that is capable of helping Earth scientists quickly identify appropriate candidate datasets and services in the global data service network. Most existing services discovery techniques, however, mainly rely on syntax or semantics-based service matchmaking between service requests and available services. Since the scale of the data service network is increasing rapidly, the run-time computational cost will soon become a bottleneck. To address this issue, this project presents a way of applying network routing mechanism to facilitate data service discovery in a service network, featuring scalability and performance. Earth data services are automatically annotated in Web Ontology Language for Services (OWL-S) based on their metadata, semantic information, and usage history. Deterministic Annealing (DA) technique is applied to dynamically organize annotated data services into a hierarchical network, where virtual routers are created to represent semantic local network featuring leading terms. Afterwards Bloom Filters are generated over virtual routers. A data service search request is transformed into a network routing problem in order to quickly locate candidate services through network hierarchy. A neural network-powered technique is applied to assure network address encoding and routing performance. A series of empirical study has been conducted to evaluate the applicability and effectiveness of the proposed approach.

  14. Spectrum and service pricing for 802.22 networks

    DEFF Research Database (Denmark)

    Stefan, Andrei Lucian; Rota, Cyril; Pratas, Nuno

    2011-01-01

    IEEE 802.22 standard is the first cognitive radio standard that targets the spectrum used by TV broadcasters. This has created a number of conflicts between mobile operators and TV operators, as the latter expects financial compensations from the entities accessing their spectrum. Thus......, in the first part of this paper a new spectrum pricing mechanism based on a Bertrand game model meant to address this issue was proposed. The novelty of the proposed spectrum pricing is related to differentiation between the propagation characteristics of the different TV bands and also the scarcity...... of channels which have an impact on the demand, and thus on the spectrum pricing. The second part of the paper exemplifies how a Bertrand game model can solve the issue of service pricing for a Wireless Regional Area Network (WRAN) operator that is trying to deploy an 802.22 network in a region where...

  15. Hormonal treatment of acne vulgaris: an update

    Directory of Open Access Journals (Sweden)

    Elsaie ML

    2016-09-01

    Full Text Available Mohamed L Elsaie Department of Dermatology and Venereology, National Research Centre, Cairo, Egypt Abstract: Acne vulgaris is a common skin condition associated with multiple factors. Although mostly presenting alone, it can likewise present with features of hyperandrogenism and hormonal discrepancies. Of note, hormonal therapies are indicated in severe, resistant-to-treatment cases and in those with monthly flare-ups and when standard therapeutic options are inappropriate. This article serves as an update to hormonal pathogenesis of acne, discusses the basics of endocrinal evaluation for patients with suspected hormonal acne, and provides an overview of the current hormonal treatment options in women. Keywords: acne, hormones, hyperandrogenism

  16. Photopneumatic therapy for the treatment of acne.

    Science.gov (United States)

    Wanitphakdeedecha, Rungsima; Tanzi, Elizabeth L; Alster, Tina S

    2009-03-01

    A wide variety of laser and light-based therapies have been utilized for acne vulgaris; however, current techniques have been limited by photosensitivity issues or inconsistent results. To determine the clinical efficacy and side-effect profile of photopneumatic therapy for the treatment of facial acne vulgaris. Twenty adults with mild to severe facial acne vulgaris received 4 successive treatments at 2-week intervals with a combined photopneumatic device (intense pulsed light [IPL]: fluences = 3.6-4.2 J/cm2; negative pressure = 3 psi). Clinical improvement was evaluated on a quartile grading scale using comparative digital photographs at baseline, and 1 month and 3 months after the final treatment. Acne lesion counts were obtained at baseline, prior to each treatment session, and at the end of the study. Modest reduction in acne lesion counts and global clinical improvement was seen in the majority of patients. Patients with severe acne experienced the most clinical improvement. Side effects were mild and limited to transient erythema and rare purpura. Most patients experienced acne worsening early in the treatment course. Photopneumatic therapy is a safe and effective treatment for acne vulgaris. Patients with more severe acne respond best to treatment.

  17. A Base Component for Network-Based Service-Oriented C4ISR Systems

    Science.gov (United States)

    2005-12-01

    access service. The main components of the service are given by two software modules, called front-end manager and service manager . A front-end...user, or by means of some installation wizard which downloads the most recent version from a designated network site. A service manager can be thought...of as a mediator between a front-end manager on the one hand and a set of network services on the other hand. A service manager is created by a

  18. The African Field Epidemiology Network--networking for effective field epidemiology capacity building and service delivery.

    Science.gov (United States)

    Gitta, Sheba Nakacubo; Mukanga, David; Babirye, Rebecca; Dahlke, Melissa; Tshimanga, Mufuta; Nsubuga, Peter

    2011-01-01

    Networks are a catalyst for promoting common goals and objectives of their membership. Public Health networks in Africa are crucial, because of the severe resource limitations that nations face in dealing with priority public health problems. For a long time, networks have existed on the continent and globally, but many of these are disease-specific with a narrow scope. The African Field Epidemiology Network (AFENET) is a public health network established in 2005 as a non-profit networking alliance of Field Epidemiology and Laboratory Training Programs (FELTPs) and Field Epidemiology Training Programs (FETPs) in Africa. AFENET is dedicated to helping ministries of health in Africa build strong, effective and sustainable programs and capacity to improve public health systems by partnering with global public health experts. The Network's goal is to strengthen field epidemiology and public health laboratory capacity to contribute effectively to addressing epidemics and other major public health problems in Africa. AFENET currently networks 12 FELTPs and FETPs in sub-Saharan Africa with operations in 20 countries. AFENET has a unique tripartite working relationship with government technocrats from human health and animal sectors, academicians from partner universities, and development partners, presenting the Network with a distinct vantage point. Through the Network, African nations are making strides in strengthening their health systems. Members are able to: leverage resources to support field epidemiology and public health laboratory training and service delivery notably in the area of outbreak investigation and response as well as disease surveillance; by-pass government bureaucracies that often hinder and frustrate development partners; and consolidate efforts of different partners channelled through the FELTPs by networking graduates through alumni associations and calling on them to offer technical support in various public health capacities as the need arises

  19. The African Field Epidemiology Network-Networking for effective field epidemiology capacity building and service delivery

    Science.gov (United States)

    Gitta, Sheba Nakacubo; Mukanga, David; Babirye, Rebecca; Dahlke, Melissa; Tshimanga, Mufuta; Nsubuga, Peter

    2011-01-01

    Networks are a catalyst for promoting common goals and objectives of their membership. Public Health networks in Africa are crucial, because of the severe resource limitations that nations face in dealing with priority public health problems. For a long time, networks have existed on the continent and globally, but many of these are disease-specific with a narrow scope. The African Field Epidemiology Network (AFENET) is a public health network established in 2005 as a non-profit networking alliance of Field Epidemiology and Laboratory Training Programs (FELTPs) and Field Epidemiology Training Programs (FETPs) in Africa. AFENET is dedicated to helping ministries of health in Africa build strong, effective and sustainable programs and capacity to improve public health systems by partnering with global public health experts. The Network's goal is to strengthen field epidemiology and public health laboratory capacity to contribute effectively to addressing epidemics and other major public health problems in Africa. AFENET currently networks 12 FELTPs and FETPs in sub-Saharan Africa with operations in 20 countries. AFENET has a unique tripartite working relationship with government technocrats from human health and animal sectors, academicians from partner universities, and development partners, presenting the Network with a distinct vantage point. Through the Network, African nations are making strides in strengthening their health systems. Members are able to: leverage resources to support field epidemiology and public health laboratory training and service delivery notably in the area of outbreak investigation and response as well as disease surveillance; by-pass government bureaucracies that often hinder and frustrate development partners; and consolidate efforts of different partners channelled through the FELTPs by networking graduates through alumni associations and calling on them to offer technical support in various public health capacities as the need arises

  20. Dynamic Vehicle Scheduling for Working Service Network with Dual Demands

    Directory of Open Access Journals (Sweden)

    Bing Li

    2017-01-01

    Full Text Available This study aims to develop some models to aid in making decisions on the combined fleet size and vehicle assignment in working service network where the demands include two types (minimum demands and maximum demands, and vehicles themselves can act like a facility to provide services when they are stationary at one location. This type of problem is named as the dynamic working vehicle scheduling with dual demands (DWVS-DD and formulated as a mixed integer programming (MIP. Instead of a large integer program, the problem is decomposed into small local problems that are guided by preset control parameters. The approach for preset control parameters is given. By introducing them into the MIP formulation, the model is reformulated as a piecewise form. Further, a piecewise method by updating preset control parameters is proposed for solving the reformulated model. Numerical experiments show that the proposed method produces better solution within reasonable computing time.

  1. First field trial of Virtual Network Operator oriented network on demand (NoD) service provisioning over software defined multi-vendor OTN networks

    Science.gov (United States)

    Li, Yajie; Zhao, Yongli; Zhang, Jie; Yu, Xiaosong; Chen, Haoran; Zhu, Ruijie; Zhou, Quanwei; Yu, Chenbei; Cui, Rui

    2017-01-01

    A Virtual Network Operator (VNO) is a provider and reseller of network services from other telecommunications suppliers. These network providers are categorized as virtual because they do not own the underlying telecommunication infrastructure. In terms of business operation, VNO can provide customers with personalized services by leasing network infrastructure from traditional network providers. The unique business modes of VNO lead to the emergence of network on demand (NoD) services. The conventional network provisioning involves a series of manual operation and configuration, which leads to high cost in time. Considering the advantages of Software Defined Networking (SDN), this paper proposes a novel NoD service provisioning solution to satisfy the private network need of VNOs. The solution is first verified in the real software defined multi-domain optical networks with multi-vendor OTN equipment. With the proposed solution, NoD service can be deployed via online web portals in near-real time. It reinvents the customer experience and redefines how network services are delivered to customers via an online self-service portal. Ultimately, this means a customer will be able to simply go online, click a few buttons and have new services almost instantaneously.

  2. Transmission design in a multimode HFC network

    Science.gov (United States)

    Cambron, G. Keith

    1996-11-01

    Contemporary hybrid fiber coaxial (HFC) networks are capable of supporting a wide range of services including traditional analog video, telephony, digital video, and data services. Each service has unique performance or service requirements. This contribution examines transmission design for one such network. Pacific Bell's advanced communications network (ACN). The design methodology begins with a set of end to end service quality objectives. Network impairments, such as noise, distortion and delay, are allocated across the network elements using a set of standard network models. These models are a representative set of the actual field designs and bound the network operating parameters. Network components, headend equipment, and customer premises equipment are specified analytically or characterized empirically in relationship to the chosen impairment set. The component parameters are then included in analytical models to estimate overall network performance. In addition to the forward path transmission considerations examined by traditional coaxial network designers, other dimensions including power consumption, traffic demand, and message latency are taken into account. Analytical models are used to estimate the effects of multiple modulation schemes within the unified network. The variability introduced by on demand services such as telephony and interactive digital services changes the base computational domain from deterministic models to stochastic ones. These models are then used to set operating parameters at measurable points throughout the network for proof of performance prior to turn up, and for ongoing performance monitoring. For closure, empirical results are compared with model projections as a way of verifying and improving the predictive models.

  3. Standard guidelines of care for acne surgery.

    Science.gov (United States)

    Khunger, Niti

    2008-01-01

    Acne surgery is the use of various surgical procedures for the treatment of postacne scarring and also, as adjuvant treatment for active acne. Surgery is indicated both in active acne and post-acne scars. PHYSICIANS' QUALIFICATIONS: Any Dermatologist can perform most acne surgery techniques as these are usually taught during postgraduation. However, certain techniques such as dermabrasion, laser resurfacing, scar revisions need specific "hands-on" training in appropriate training centers. Most acne surgery procedures can be performed in a physician's minor procedure room. However, full-face dermabrasion and laser resurfacing need an operation theatre in a hospital setting. ACTIVE ACNE: Surgical treatment is only an adjunct to medical therapy, which remains the mainstay of treatment. Comedone extraction is a process of applying simple mechanical pressure with a comedone extractor, to extract the contents of the blocked pilosebaceous follicle. Superficial chemical peel is a process of applying a chemical agent to the skin, so as to cause controlled destruction of the epidermis leading to exfoliation. Glycolic acid, salicylic acid and trichloroacetic acid are commonly used peeling agents for the treatment of active acne and superficial acne scars. CRYOTHERAPY: Cryoslush and cryopeel are used for the treatment of nodulocystic acne. Intralesional corticosteroids are indicated for the treatment of nodules, cysts and keloidal acne scars. Nonablative lasers and light therapy using Blue light, non ablative radiofrequency, Nd:YAG laser, IPL (Intense Pulsed Light), PDT (Photodynamic Therapy), pulse dye laser and light and heat energy machines have been used in recent years for the treatment of active inflammatory acne and superficial acne scars. Proper counseling is very important in the treatment of acne scars. Treatment depends on the type of acne scars; a patient may need more than one type of treatment. Subcision is a treatment to break the fibrotic strands that tether

  4. Standard guidelines of care for acne surgery

    Directory of Open Access Journals (Sweden)

    Khunger Niti

    2008-03-01

    Full Text Available Acne surgery is the use of various surgical procedures for the treatment of postacne scarring and also, as adjuvant treatment for active acne. Surgery is indicated both in active acne and post-acne scars. Physicians′ qualifications: Any Dermatologist can perform most acne surgery techniques as these are usually taught during postgraduation. However, certain techniques such as dermabrasion, laser resurfacing, scar revisions need specific "hands-on" training in appropriate training centers. Facility: Most acne surgery procedures can be performed in a physician′s minor procedure room. However, full-face dermabrasion and laser resurfacing need an operation theatre in a hospital setting. Active acne: Surgical treatment is only an adjunct to medical therapy, which remains the mainstay of treatment. Comedone extraction is a process of applying simple mechanical pressure with a comedone extractor, to extract the contents of the blocked pilosebaceous follicle. Superficial chemical peel is a process of applying a chemical agent to the skin, so as to cause controlled destruction of the epidermis leading to exfoliation. Glycolic acid, salicylic acid and trichloroacetic acid are commonly used peeling agents for the treatment of active acne and superficial acne scars. Cryotherapy: Cryoslush and cryopeel are used for the treatment of nodulocystic acne. Intralesional corticosteroids are indicated for the treatment of nodules, cysts and keloidal acne scars. Nonablative lasers and light therapy using Blue light, non ablative radiofrequency, Nd:YAG laser, IPL (Intense Pulsed Light, PDT (Photodynamic Therapy, pulse dye laser and light and heat energy machines have been used in recent years for the treatment of active inflammatory acne and superficial acne scars. Proper counseling is very important in the treatment of acne scars. Treatment depends on the type of acne scars; a patient may need more than one type of treatment. Subcision is a treatment to break the

  5. Distributed Denial of Service Tools, Trin00, Tribe Flood Network, Tribe Flood Network 2000 and Stacheldraht.

    Energy Technology Data Exchange (ETDEWEB)

    Criscuolo, P. J.

    2000-02-14

    One type of attack on computer systems is know as a Denial of Service (DoS) attack. A DoS attack is designed to prevent legitimate users from using a system. Traditional Denial of Service attacks are done by exploiting a buffer overflow, exhausting system resources, or exploiting a system bug that results in a system that is no longer functional. In the summer of 1999, a new breed of attack has been developed called Distributed Denial of Service (DDoS) attack. Several educational and high capacity commercial sites have been affected by these DDoS attacks. A DDoS attack uses multiple machines operating in concert to attack a network or site. There is very little that can be done if you are the target of a DDoS. The nature of these attacks cause so much extra network traffic that it is difficult for legitimate traffic to reach your site while blocking the forged attacking packets. The intent of this paper is to help sites not be involved in a DDoS attack. The first tools developed to perpetrate the DDoS attack were Trin00 and Tribe Flood Network (TFN). They spawned the next generation of tools called Tribe Flood Network 2000 (TFN2K) and Stacheldraht (German for Barb Wire). These DDoS attack tools are designed to bring one or more sites down by flooding the victim with large amounts of network traffic originating at multiple locations and remotely controlled by a single client. This paper discusses how these DDoS tools work, how to detect them, and specific technical information on each individual tool. It is written with the system administrator in mind. It assumes that the reader has basic knowledge of the TCP/IP Protocol.

  6. Defending networks against denial-of-service attacks

    Science.gov (United States)

    Gelenbe, Erol; Gellman, Michael; Loukas, George

    2004-11-01

    Denial of service attacks, viruses and worms are common tools for malicious adversarial behavior in networks. Experience shows that over the last few years several of these techniques have probably been used by governments to impair the Internet communications of various entities, and we can expect that these and other information warfare tools will be used increasingly as part of hostile behavior either independently, or in conjunction with other forms of attack in conventional or asymmetric warfare, as well as in other forms of malicious behavior. In this paper we concentrate on Distributed Denial of Service Attacks (DDoS) where one or more attackers generate flooding traffic and direct it from multiple sources towards a set of selected nodes or IP addresses in the Internet. We first briefly survey the literature on the subject, and discuss some examples of DDoS incidents. We then present a technique that can be used for DDoS protection based on creating islands of protection around a critical information infrastructure. This technique, that we call the CPN-DoS-DT (Cognitive Packet Networks DoS Defence Technique), creates a self-monitoring sub-network surrounding each critical infrastructure node. CPN-DoS-DT is triggered by a DDoS detection scheme, and generates control traffic from the objects of the DDoS attack to the islands of protection where DDOS packet flows are destroyed before they reach the critical infrastructure. We use mathematical modelling, simulation and experiments on our test-bed to show the positive and negative outcomes that may result from both the attack, and the CPN-DoS-DT protection mechanism, due to imperfect detection and false alarms.

  7. Multi-domain service dispatching scheme based on SDON virtualized network

    Science.gov (United States)

    Zheng, Mingfang; Li, Hui; Ji, Yuefeng

    2017-10-01

    With the information flow in the network growing rapidly and the size of network extending gradually, it is essential that SDON networking supports multi-domain optical services. Since the type of network has moved toward complicated and converged, the disparate network resource has interlaced, an isomerized network situation is the trend in the future. Accordingly, end-to-end (E2E) services have shifted from a single service provider domain towards a multi-domain service provider. On this condition, the traditional isolated networking mode is so difficult to meet the current demand. E2E multi-domain services are the trend in the future. This paper proposes a multi-domain service dispatching scheme based on SDON virtualized network. By sending concurrent http requests to controller multiple single-domain controllers, web service management will manage optical devices and achieve E2E multi-domain service requests over this scheme. The management layer establishes E2E services dispatching system in multi-domain virtual optical network and it changes the present situation of disparate single service provider incompatibility. The experiment also indicates the reality possibility of the multi-domain dispatching scheme. This scheme will provide basis for the large scale multi-domain networking based on SDON in the future.

  8. A comparative study of biological and metabolic biomarkers between healthy individuals and patients with acne vulgaris: A cross-sectional study protocol.

    Science.gov (United States)

    Kim, Kyuseok; Ha, Injin; Kim, Eunok; Kim, Kyunglee

    2017-11-01

    Acne is a multifactorial dermatosis, which is influenced not only by hormones but also by the biochemical relationship between them and the pilosebaceous unit. Inflammatory cytokines, chemokines, active oxygen, and zinc are known to be associated with the development of acne. Further, steroid metabolism is known as one of the important factors related to sebum secretion and comedone formation in acne. However, there is a lack of studies comparing these human biomarkers between healthy individuals and patients with acne. In particular, no study has investigated the relationship between human biomarkers and patterns of acne yet.The purpose of this study is to investigate diagnostic human biomarkers in acne by comparing the biological and metabolic biomarkers between healthy individuals and patients with acne and identify the relationship between human biomarkers and patterns of acne.This study is a protocol for a cross-sectional study. Forty healthy participants and 60 patients with acne will be recruited at 1 center. We will collect their blood samples and analyze the molecular biological and metabolic biomarkers (cytokines, chemokines, reactive oxygen species, corticotropin-releasing hormone, zinc, amino acid, 1-carbon metabolite, lipid metabolite, etc.). Further, we will administer questionnaires regarding their diet, sleep, stress, and other factors relating to acne and measure their skin elasticity.The study protocol was approved by the Institutional Review Board of Oriental Medical Hospital at Kyung Hee Medical Center (KOMCIRB-161118-HR-062). Written informed consent will be obtained from all the participants. The trial was registered in the Clinical Research Information Service, Republic of Korea: KCT0002212.This trial will provide evidence regarding diagnostic human biomarkers in acne and the relationship between the human biomarkers and patterns of acne.

  9. The flexible gene pool of Propionibacterium acnes

    DEFF Research Database (Denmark)

    Brüggemann, Holger; Lomholt, Hans B; Kilian, Mogens

    2012-01-01

    Propionibacterium acnes is a Gram-positive bacterium that is intimately associated with humans. The nature and consequences of this symbiosis are poorly understood; it might comprise both mutualistic and parasitic properties. Recent advances in distinguishing phylotypes of P. acnes have revealed ...

  10. Acne | Lambert | South African Family Practice

    African Journals Online (AJOL)

    Acne vulgaris is a common skin condition with a high prevalence in teenagers and young adults. It is a condition of the pilosebaceous follicles, resulting in comedones, papules, pustules or nodules which occur primarily on the face, but which may also present on other areas of the body. Although acne is not physically ...

  11. Differences in Beliefs about Psychological Services in the Relationship between Sociorace and One's Social Network

    Science.gov (United States)

    Walter, Jeffrey P.; Yon, Kyu Jin; Skovholt, Thomas M.

    2012-01-01

    The roles of previous psychological service use and social network variables in beliefs about psychological services were examined with 184 college students. Having friends and family members who used psychological services, being female, and having used psychological services positively related with beliefs about psychological services.…

  12. Self-reported acne is not associated with prostate cancer

    NARCIS (Netherlands)

    Cremers, R.G.H.M.; Aben, K.K.H.; Vermeulen, S.; Heijer, M. den; Oort, I.M. van; Kerkhof, P.C.M. van de; Schalken, J.A.; Kiemeney, L.A.L.M.

    2014-01-01

    OBJECTIVE: Some studies have suggested an inverse association between acne vulgaris and the acne-related bacterium Propionibacterium acnes and prostate cancer (PCa). Self-reported acne might be an easily obtainable marker to identify men at relatively low risk of PCa and might be incorporated into

  13. Self-reported acne is not associated with prostate cancer

    NARCIS (Netherlands)

    Cremers, R.G.; Aben, K.K.; Verrneulen, S.H.; den Heijer, M.; van Oort, I.M.; van de Kerkhof, P.C.; Schalken, JA; Kiemeney, L.A.

    2014-01-01

    Objective: Some studies have suggested an inverse association between acne vulgaris and the acne-related bacterium Propionibacterium acnes and prostate cancer (PCa). Self-reported acne might be an easily obtainable marker to identify men at relatively low risk of PCa and might be incorporated into

  14. Design and implementation of interface units for high speed fiber optics local area networks and broadband integrated services digital networks

    Science.gov (United States)

    Tobagi, Fouad A.; Dalgic, Ismail; Pang, Joseph

    1990-01-01

    The design and implementation of interface units for high speed Fiber Optic Local Area Networks and Broadband Integrated Services Digital Networks are discussed. During the last years, a number of network adapters that are designed to support high speed communications have emerged. This approach to the design of a high speed network interface unit was to implement package processing functions in hardware, using VLSI technology. The VLSI hardware implementation of a buffer management unit, which is required in such architectures, is described.

  15. Support networks and people with physical disabilities: social inclusion and access to health services

    National Research Council Canada - National Science Library

    Holanda, Cristina Marques de Almeida; De Andrade, Fabienne Louise Juvêncio Paes; Bezerra, Maria Aparecida; Nascimento, João Paulo da Silva; Neves, Robson da Fonseca; Alves, Simone Bezerra; Ribeiro, Kátia Suely Queiroz Silva

    2015-01-01

    This study seeks to identify the formation of social support networks of people with physical disabilities, and how these networks can help facilitate access to health services and promote social inclusion...

  16. IRLT: Integrating Reputation and Local Trust for Trustworthy Service Recommendation in Service-Oriented Social Networks.

    Directory of Open Access Journals (Sweden)

    Zhiquan Liu

    Full Text Available With the prevalence of Social Networks (SNs and services, plenty of trust models for Trustworthy Service Recommendation (TSR in Service-oriented SNs (S-SNs have been proposed. The reputation-based schemes usually do not contain user preferences and are vulnerable to unfair rating attacks. Meanwhile, the local trust-based schemes generally have low reliability or even fail to work when the trust path is too long or does not exist. Thus it is beneficial to integrate them for TSR in S-SNs. This work improves the state-of-the-art Combining Global and Local Trust (CGLT scheme and proposes a novel Integrating Reputation and Local Trust (IRLT model which mainly includes four modules, namely Service Recommendation Interface (SRI module, Local Trust-based Trust Evaluation (LTTE module, Reputation-based Trust Evaluation (RTE module and Aggregation Trust Evaluation (ATE module. Besides, a synthetic S-SN based on the famous Advogato dataset is deployed and the well-known Discount Cumulative Gain (DCG metric is employed to measure the service recommendation performance of our IRLT model with comparing to that of the excellent CGLT model. The results illustrate that our IRLT model is slightly superior to the CGLT model in honest environment and significantly outperforms the CGLT model in terms of the robustness against unfair rating attacks.

  17. Multi-layer service function chaining scheduling based on auxiliary graph in IP over optical network

    Science.gov (United States)

    Li, Yixuan; Li, Hui; Liu, Yuze; Ji, Yuefeng

    2017-10-01

    Software Defined Optical Network (SDON) can be considered as extension of Software Defined Network (SDN) in optical networks. SDON offers a unified control plane and makes optical network an intelligent transport network with dynamic flexibility and service adaptability. For this reason, a comprehensive optical transmission service, able to achieve service differentiation all the way down to the optical transport layer, can be provided to service function chaining (SFC). IP over optical network, as a promising networking architecture to interconnect data centers, is the most widely used scenarios of SFC. In this paper, we offer a flexible and dynamic resource allocation method for diverse SFC service requests in the IP over optical network. To do so, we firstly propose the concept of optical service function (OSF) and a multi-layer SFC model. OSF represents the comprehensive optical transmission service (e.g., multicast, low latency, quality of service, etc.), which can be achieved in multi-layer SFC model. OSF can also be considered as a special SF. Secondly, we design a resource allocation algorithm, which we call OSF-oriented optical service scheduling algorithm. It is able to address multi-layer SFC optical service scheduling and provide comprehensive optical transmission service, while meeting multiple optical transmission requirements (e.g., bandwidth, latency, availability). Moreover, the algorithm exploits the concept of Auxiliary Graph. Finally, we compare our algorithm with the Baseline algorithm in simulation. And simulation results show that our algorithm achieves superior performance than Baseline algorithm in low traffic load condition.

  18. The QAP weighted network analysis method and its application in international services trade

    Science.gov (United States)

    Xu, Helian; Cheng, Long

    2016-04-01

    Based on QAP (Quadratic Assignment Procedure) correlation and complex network theory, this paper puts forward a new method named QAP Weighted Network Analysis Method. The core idea of the method is to analyze influences among relations in a social or economic group by building a QAP weighted network of networks of relations. In the QAP weighted network, a node depicts a relation and an undirect edge exists between any pair of nodes if there is significant correlation between relations. As an application of the QAP weighted network, we study international services trade by using the QAP weighted network, in which nodes depict 10 kinds of services trade relations. After the analysis of international services trade by QAP weighted network, and by using distance indicators, hierarchy tree and minimum spanning tree, the conclusion shows that: Firstly, significant correlation exists in all services trade, and the development of any one service trade will stimulate the other nine. Secondly, as the economic globalization goes deeper, correlations in all services trade have been strengthened continually, and clustering effects exist in those services trade. Thirdly, transportation services trade, computer and information services trade and communication services trade have the most influence and are at the core in all services trade.

  19. Novel Network Services for Supporting Big Data Science Research

    OpenAIRE

    Chung, Joaquin; Donovan, Sean; Bezerra, Jeronimo; Morgan, Heidi; Ibarra, Julio; Clark, Russ; Owen, Henry

    2017-01-01

    To interconnect research facilities across wide geographic areas, network operators deploy science networks, also referred to as Research and Education (R&E) networks. These networks allow experimenters to establish dedicated network connections between research facilities for transferring large amounts of data. Recently, R&E networks have started using Software-Defined Networking (SDN) and Software-Defined Exchanges (SDX) for deploying these connections. AtlanticWave/SDX is a response to the...

  20. Applied Ontology Engineering in Cloud Services, Networks and Management Systems

    CERN Document Server

    Serrano Orozco, J Martín

    2012-01-01

    Metadata standards in today’s ICT sector are proliferating at unprecedented levels, while automated information management systems collect and process exponentially increasing quantities of data. With interoperability and knowledge exchange identified as a core challenge in the sector, this book examines the role ontology engineering can play in providing solutions to the problems of information interoperability and linked data. At the same time as introducing basic concepts of ontology engineering, the book discusses methodological approaches to formal representation of data and information models, thus facilitating information interoperability between heterogeneous, complex and distributed communication systems. In doing so, the text advocates the advantages of using ontology engineering in telecommunications systems. In addition, it offers a wealth of guidance and best-practice techniques for instances in which ontology engineering is applied in cloud services, computer networks and management systems. �...

  1. Service-Aware Retransmission Control in Cellular Networks

    Directory of Open Access Journals (Sweden)

    Nadhir Ben Halima

    2010-01-01

    Full Text Available This paper proposes a service-aware cross-layer approach between application/transport layers on the mobile terminal and link layer on the wireless base station to enable dynamic control on the level of per-packet error protection for multimedia data streams. Specifically, in the context of cellular networks, the proposed scheme enables the mobile terminal to specify to the base station the desired level of Hybrid ARQ (HARQ protection by using an in-band control feedback channel. Such protection is dynamically adapted on a per-packet basis and depends on the perceptual importance of different packets as well as on the reception history of the flow. Experimental results demonstrate the potential benefits deriving from the proposed strategy either for audio and video real-time streams as well as for TCP-based data transfers.

  2. Multiple Activities of Punica granatum Linne against Acne Vulgaris

    OpenAIRE

    Chia-Jung Lee; Lih-Geeng Chen; Wen-Li Liang; Ching-Chiung Wang

    2017-01-01

    Acne is a common skin condition with sebum overproduction, hyperkeratosis, Propionibacterium acnes (P. acnes) and Staphylococcus aureus, and inflammation. Punica granatum (pomegranate) is well-known for its anti-inflammatory effects; however, few studies have discussed the anti-acne effects of pomegranate. In this study, we found that pomegranate extract (PG-E) significantly reduced P. acnes-induced edema in Wistar rat ears. Therefore, an evaluation platform using multiple pathogenic mechanis...

  3. Effects of fish oil supplementation on inflammatory acne

    OpenAIRE

    Khayef Golandam; Young Julia; Burns-Whitmore Bonny; Spalding Thomas

    2012-01-01

    Abstract Background Given that acne is a rare condition in societies with higher consumption of omega-3 (n-3) relative to omega-6 (n-6) fatty acids, supplementation with n-3 may suppress inflammatory cytokine production and thereby reduce acne severity. Methods 13 individuals with inflammatory acne were given three grams of fish oil containing 930 mg of EPA to their unchanged diet and existing acne remedies for 12 weeks. Acne was assessed using an overall severity grading scale, total inflamm...

  4. Coordination in networks for improved mental health service

    Directory of Open Access Journals (Sweden)

    Johan Hansson

    2010-08-01

    Full Text Available Background: Well-organised clinical cooperation between health and social services has been difficult to achieve in Sweden as in other countries. Purpose: This paper presents an empirical study of a mental health coordination network in one area in Stockholm. The aim was to describe the development and nature of coordination within a mental health and social care consortium and to assess the impact on care processes and client outcomes. Method: Data was gathered through interviews with coordina­tors from three rehabilitation units. The interviews focused on coordination activities aimed at supporting the clients’ needs and investigated how the coordinators acted according to the consortium's holistic approach. Data on The Camberwell Assess­ment of Need (CAN-S showing clients’ satisfaction was used to assess on set of outcomes. Findings: The findings revealed different coordination activities and factors both helping and hindering the network coordination activities. One factor helping was the history of local and personal informal cooperation and shared responsibilities evident. Unclear roles and routines hindered cooperation Practical value: The contribution is an empirical example and a model for organisations establishing structures for network coordination. One lesson for current policy about integrated health care is to adapt and implement ”pair coordinators” where full structural integration is not possible. Another lesson, based on the idea of patient quality by coordinated care, is specific to adapt the work of the local psychiatric addictive team – an independent special team in the psychiatric outpatient care serving psychotic clients with complex addictive problems.

  5. Coordination in networks for improved mental health service

    Directory of Open Access Journals (Sweden)

    Johan Hansson

    2010-08-01

    Full Text Available Background: Well-organised clinical cooperation between health and social services has been difficult to achieve in Sweden as in other countries.Purpose: This paper presents an empirical study of a mental health coordination network in one area in Stockholm. The aim was to describe the development and nature of coordination within a mental health and social care consortium and to assess the impact on care processes and client outcomes.Method: Data was gathered through interviews with coordina­tors from three rehabilitation units. The interviews focused on coordination activities aimed at supporting the clients’ needs and investigated how the coordinators acted according to the consortium's holistic approach. Data on The Camberwell Assess­ment of Need (CAN-S showing clients’ satisfaction was used to assess on set of outcomes. Findings: The findings revealed different coordination activities and factors both helping and hindering the network coordination activities. One factor helping was the history of local and personal informal cooperation and shared responsibilities evident. Unclear roles and routines hindered cooperationPractical value: The contribution is an empirical example and a model for organisations establishing structures for network coordination. One lesson for current policy about integrated health care is to adapt and implement ”pair coordinators” where full structural integration is not possible. Another lesson, based on the idea of patient quality by coordinated care, is specific to adapt the work of the local psychiatric addictive team – an independent special team in the psychiatric outpatient care serving psychotic clients with complex addictive problems.

  6. Cross-Layer Service Discovery Mechanism for OLSRv2 Mobile Ad Hoc Networks

    Directory of Open Access Journals (Sweden)

    M. Isabel Vara

    2015-07-01

    Full Text Available Service discovery plays an important role in mobile ad hoc networks (MANETs. The lack of central infrastructure, limited resources and high mobility make service discovery a challenging issue for this kind of network. This article proposes a new service discovery mechanism for discovering and advertising services integrated into the Optimized Link State Routing Protocol Version 2 (OLSRv2. In previous studies, we demonstrated the validity of a similar service discovery mechanism integrated into the previous version of OLSR (OLSRv1. In order to advertise services, we have added a new type-length-value structure (TLV to the OLSRv2 protocol, called service discovery message (SDM, according to the Generalized MANET Packet/Message Format defined in Request For Comments (RFC 5444. Each node in the ad hoc network only advertises its own services. The advertisement frequency is a user-configurable parameter, so that it can be modified depending on the user requirements. Each node maintains two service tables, one to store information about its own services and another one to store information about the services it discovers in the network. We present simulation results, that compare our service discovery integrated into OLSRv2 with the one defined for OLSRv1 and with the integration of service discovery in Ad hoc On-demand Distance Vector (AODV protocol, in terms of service discovery ratio, service latency and network overhead.

  7. Collaboration, learning and innovation across outsourced services value networks software services outsourcing in China

    CERN Document Server

    Abbott, Pamela; Du, Rong

    2015-01-01

    This book collects and reports on the results of a study conducted on the Chinese Software and Services Outsourcing (SSO) industry, focusing on one of its main players as a key case study. Two sets of research findings are presented: first, the knowledge management and communication processes inherent within a highly collaborative software development project between the case study company and one of its long-term UK clients are explored and distilled into specific practices; second, at the organizational level, the strategies used by the company to build and exploit capabilities and to dynamically configure resources to promote specific value positions along its outsourced services value networks are identified and discussed. The significance of these findings for similar China-based global high-tech firms and the value of this organizational form in moving closer to the goals of the 2020 enterprise vision are both discussed, along with the implications of the findings for EU/UK businesses operating in simil...

  8. The impacts of network competence, knowledge sharing on service innovation performance: Moderating role of relationship quality

    Directory of Open Access Journals (Sweden)

    Zaoquan Jian

    2013-03-01

    Full Text Available Purpose: To examine how network competence, knowledge sharing and relationship quality affect service innovation performanceDesign/methodology/approach: Empirical ResearchFindings: 1 Both enterprise’s network competence and knowledge sharing have distinct positive impact on SIP; (2 Knowledge sharing partially mediates the effect of network competence on SIP. (3 Relationship quality positively moderates the effect of network competence on knowledge sharing, and the effect of knowledge sharing on SIP. (4 Relationship quality does not positively moderate the effect of network competence on SIP.Originality/value: This study has enriched current understanding of the relationship among network competence, knowledge sharing, relationship quality and service innovation performance.

  9. Social network based dynamic transit service through the OMITS system.

    Science.gov (United States)

    2014-02-01

    The Open Mode Integrated Transportation System (OMITS) forms a sustainable information infrastructure for communication within and between the mobile/Internet network, the roadway : network, and the users social network. It manipulates the speed g...

  10. ACNE VULGARIS TREATMENT : THE CURRENT SCENARIO

    Science.gov (United States)

    Rathi, Sanjay K

    2011-01-01

    Acne Vulgaris is one of the most common skin disorders which dermatologists have to treat. It mainly affect adolescent, though may present at any age. In recent years, due to better understanding of the pathogenesis of acne, new therapeutic modalities and various permutation and combinations have been designed. In topical agents; benzoyl peroxide, antibiotics, retinoids, etc are the mainstay of treatment; can be given in combinations. While systemic therapy includes oral antibiotics, hormonal therapy, and isotretinoin, depending upon the need of patients it has to be selected. Physical treatment in the form of lesion removal, photo-therapy is also helpful in few of them. Since various old and new topical and systemic agents are available to treat acne, it sometime confuse treating dermatologist. To overcome this, panel of physicians and researchers worked together as a global alliance and task force to improve outcomes in acne treatment. They have tried to give consensus recommendation for the treatment of acne. Successful management of acne needs careful selection of anti-acne agents according to clinical presentation and individual patient needs. PMID:21572783

  11. Acne vulgaris treatment : The Current Scenario

    Directory of Open Access Journals (Sweden)

    Sanjay K Rathi

    2011-01-01

    Full Text Available Acne Vulgaris is one of the most common skin disorders which dermatologists have to treat. It mainly affect adolescent, though may present at any age. In recent years, due to better understanding of the pathogenesis of acne, new therapeutic modalities and various permutation and combinations have been designed. In topical agents; benzoyl peroxide, antibiotics, retinoids, etc are the mainstay of treatment; can be given in combinations. While systemic therapy includes oral antibiotics, hormonal therapy, and isotretinoin, depending upon the need of patients it has to be selected. Physical treatment in the form of lesion removal, photo-therapy is also helpful in few of them. Since various old and new topical and systemic agents are available to treat acne, it sometime confuse treating dermatologist. To overcome this, panel of physicians and researchers worked together as a global alliance and task force to improve outcomes in acne treatment. They have tried to give consensus recommendation for the treatment of acne. Successful management of acne needs careful selection of anti-acne agents according to clinical presentation and individual patient needs.

  12. A review of phytotherapy of Acne vulgaris

    Directory of Open Access Journals (Sweden)

    Marija Glavas Dodov

    2009-11-01

    Full Text Available Acne vulgaris (acne is a cutaneous pleomorphic disorder of the pilosebaceous unit involving abnormalities in sebum production and is characterized by both inflammatory (papules, pustules and nodules and non-inflammatory (comedones, open and closed lesions. Propionibacterium acnes and Staphylococcus epidermidis are common pus-forming microbes responsible for the development of various forms of acne. This disease remains a common condition in industrialized societies, with many mainstream treatment options available. There are many acne products on the market, and making an appropriate selection can be daunting. Common therapies that are used for the treatment of acne include topical, systemic, hormonal, herbal and combination therapy. Topically used agents are benzoyl peroxide, antibiotics and retinoid. Systemically used agents are antibiotics and isotretinoin. However, all such treatments carry risks and none is completely satisfactory. Natural alternatives are gaining greater research support, and have much to offer clinically in this disorder. This review focuses primarily on herbal treatments for acne that show scientific evidence of clinical efficacy, as well as the more common herbs shown to be useful in the treatment of this dermatologic disorder.

  13. Acne scars in 18-year-old male adolescents: a population-based study of prevalence and associated factors*

    Science.gov (United States)

    Lauermann, Fernanda Tcatch; de Almeida Jr., Hiram Larangeira; Duquia, Rodrigo Pereira; de Souza, Paulo Ricardo Martins; Breunig, Juliano de Avelar

    2016-01-01

    Background Acne vulgaris is a pilosebaceous follicle disorder affecting over 85% of adolescents to some degree. It frequently causes psychological distress that may persist into adulthood due to scarring. Little information about post-acne scarring epidemiology is available. Objectives To describe prevalence, distribution patterns and associated factors of acne scarring in young males, drawing on a representative population sample from a southern Brazilian city. Methods A cross-sectional study was undertaken during presentation for military service, which is compulsory for all 18-year-old males. A questionnaire was applied, covering topics like diet, smoking habits, ethnicity, family structure, socio-economic level, as well as specific questions about active acne and resulting scars. Dermatologists conducted the clinical examination. Results A total of 2,201 male adolescents were interviewed and examined. The overall prevalence of acne scarring was 22%. The malar region was the most frequently involved, present in 80% of affected individuals, followed by the frontal region (31.5%), back (17%), anterior chest (8.2%) and mentonian region (6.4%). Correlation between the intensity of clinical acne and the presence of scars was found, but no association was observed with educational level, smoking, ethnicity, obesity or socio-economic status. Conclusions There is a high prevalence of acne scars among this population. This is the first study to ascertain a correlation between acne scarring and factors such as socio-economic status and educational level. The direct relation between acne severity and scarring indicates that prompt and effective treatment is the best way to reduce scarring. PMID:27438194

  14. Acne scars in 18-year-old male adolescents: a population-based study of prevalence and associated factors.

    Science.gov (United States)

    Lauermann, Fernanda Tcatch; Almeida, Hiram Larangeira de; Duquia, Rodrigo Pereira; Souza, Paulo Ricardo Martins de; Breunig, Juliano de Avelar

    2016-01-01

    Acne vulgaris is a pilosebaceous follicle disorder affecting over 85% of adolescents to some degree. It frequently causes psychological distress that may persist into adulthood due to scarring. Little information about post-acne scarring epidemiology is available. To describe prevalence, distribution patterns and associated factors of acne scarring in young males, drawing on a representative population sample from a southern Brazilian city. A cross-sectional study was undertaken during presentation for military service, which is compulsory for all 18-year-old males. A questionnaire was applied, covering topics like diet, smoking habits, ethnicity, family structure, socio-economic level, as well as specific questions about active acne and resulting scars. Dermatologists conducted the clinical examination. A total of 2,201 male adolescents were interviewed and examined. The overall prevalence of acne scarring was 22%. The malar region was the most frequently involved, present in 80% of affected individuals, followed by the frontal region (31.5%), back (17%), anterior chest (8.2%) and mentonian region (6.4%). Correlation between the intensity of clinical acne and the presence of scars was found, but no association was observed with educational level, smoking, ethnicity, obesity or socio-economic status. There is a high prevalence of acne scars among this population. This is the first study to ascertain a correlation between acne scarring and factors such as socio-economic status and educational level. The direct relation between acne severity and scarring indicates that prompt and effective treatment is the best way to reduce scarring.

  15. Acne image analysis: lesion localization and classification

    Science.gov (United States)

    Abas, Fazly Salleh; Kaffenberger, Benjamin; Bikowski, Joseph; Gurcan, Metin N.

    2016-03-01

    Acne is a common skin condition present predominantly in the adolescent population, but may continue into adulthood. Scarring occurs commonly as a sequel to severe inflammatory acne. The presence of acne and resultant scars are more than cosmetic, with a significant potential to alter quality of life and even job prospects. The psychosocial effects of acne and scars can be disturbing and may be a risk factor for serious psychological concerns. Treatment efficacy is generally determined based on an invalidated gestalt by the physician and patient. However, the validated assessment of acne can be challenging and time consuming. Acne can be classified into several morphologies including closed comedones (whiteheads), open comedones (blackheads), papules, pustules, cysts (nodules) and scars. For a validated assessment, the different morphologies need to be counted independently, a method that is far too time consuming considering the limited time available for a consultation. However, it is practical to record and analyze images since dermatologists can validate the severity of acne within seconds after uploading an image. This paper covers the processes of region-ofinterest determination using entropy-based filtering and thresholding as well acne lesion feature extraction. Feature extraction methods using discrete wavelet frames and gray-level co-occurence matrix were presented and their effectiveness in separating the six major acne lesion classes were discussed. Several classifiers were used to test the extracted features. Correct classification accuracy as high as 85.5% was achieved using the binary classification tree with fourteen principle components used as descriptors. Further studies are underway to further improve the algorithm performance and validate it on a larger database.

  16. Complementary therapies for acne vulgaris.

    Science.gov (United States)

    Cao, Huijuan; Yang, Guoyan; Wang, Yuyi; Liu, Jian Ping; Smith, Caroline A; Luo, Hui; Liu, Yueming

    2015-01-19

    Acne is a chronic skin disease characterised by inflamed spots and blackheads on the face, neck, back, and chest. Cysts and scarring can also occur, especially in more severe disease. People with acne often turn to complementary and alternative medicine (CAM), such as herbal medicine, acupuncture, and dietary modifications, because of their concerns about the adverse effects of conventional medicines. However, evidence for CAM therapies has not been systematically assessed. To assess the effects and safety of any complementary therapies in people with acne vulgaris. We searched the following databases from inception up to 22 January 2014: the Cochrane Skin Group Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL; 2014,Issue 1), MEDLINE (from 1946), Embase (from 1974), PsycINFO (from 1806), AMED (from 1985), CINAHL (from 1981), Scopus (from 1966), and a number of other databases listed in the Methods section of the review. The Cochrane CAM Field Specialised Register was searched up to May 2014. We also searched five trials registers and checked the reference lists of articles for further references to relevant trials. We included parallel-group randomised controlled trials (or the first phase data of randomised cross-over trials) of any kind of CAM, compared with no treatment, placebo, or other active therapies, in people with a diagnosis of acne vulgaris. Three authors collected data from each included trial and evaluated the methodological quality independently. They resolved disagreements by discussion and, as needed, arbitration by another author. We included 35 studies, with a total of 3227 participants. We evaluated the majority as having unclear risk of selection, attrition, reporting, detection, and other biases. Because of the clinical heterogeneity between trials and the incomplete data reporting, we could only include four trials in two meta-analyses, with two trials in each meta-analysis. The categories of CAM included

  17. Focal Acne Scar Treatment (FAST), a new approach to atrophic acne scars: a case series.

    Science.gov (United States)

    Schweiger, Eric S; Sundick, Lauren

    2013-10-01

    Acne scars are a common concern in dermatology. Fractional CO2 laser resurfacing is a recent addition in our armamentarium of treatment options for acne scars and has been shown to be an excellent option for patients with atrophic acne scars. Patients with acne scars receiving fractional CO2 resurfacing usually have both the acne scars and surrounding unscarred areas treated in common practice. There has yet to be a study that looked at the implications of only focally treating the acne scars while leaving surrounding normal skin untreated. To evaluate the safety and efficacy of a focal approach to fractional CO2 laser treatment for acne scars, coined "Focal Acne Scar Treatment" or "FAST" This retrospective case series was conducted at Schweiger Dermatology, in New York, NY, with patients treated from November 2011 through May 2012. Overall, six patients (ages 18 to 48) were treated with the fractional CO2 laser resurfacing, using a so called "FAST" technique treating only the acne scars and leaving normal skin untreated. Evaluation was based on physician and patient assessment of improvement at one week and four weeks post-treatment. All six patients treated with the Focal Acne Scar Treatment technique of fractional CO2 laser resurfacing had significant improvement post treatment ranging from 40% to 70% as estimated by the treating dermatologist and patient at four weeks post treatment. Patient satisfaction was high following FAST method. Temporary post-inflammatory hyperpigmentation was seen in two patients but resolved after a single 1550 nm Erbium Glass fractional laser treatment. The Focal Acne Scar Treatment technique is an effective method of improving the appearance of atrophic acne scars. Higher energy and density levels can be used when utilizing this technique, resulting in improved outcomes when compared with whole face fractional CO2 laser resurfacing. Healing is improved and faster with this technique and no increased incidence of permanent adverse

  18. 47 CFR 73.4157 - Network signals which adversely affect affiliate broadcast service.

    Science.gov (United States)

    2010-10-01

    ... affiliate broadcast service. 73.4157 Section 73.4157 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) BROADCAST RADIO SERVICES RADIO BROADCAST SERVICES Rules Applicable to All Broadcast Stations § 73.4157 Network signals which adversely affect affiliate broadcast service. See Public Notice, FCC 79-387...

  19. Hormonal treatment of acne vulgaris: an update

    Science.gov (United States)

    Elsaie, Mohamed L

    2016-01-01

    Acne vulgaris is a common skin condition associated with multiple factors. Although mostly presenting alone, it can likewise present with features of hyperandrogenism and hormonal discrepancies. Of note, hormonal therapies are indicated in severe, resistant-to-treatment cases and in those with monthly flare-ups and when standard therapeutic options are inappropriate. This article serves as an update to hormonal pathogenesis of acne, discusses the basics of endocrinal evaluation for patients with suspected hormonal acne, and provides an overview of the current hormonal treatment options in women. PMID:27621661

  20. Population genetic analysis of Propionibacterium acnes identifies a subpopulation and epidemic clones associated with acne.

    Directory of Open Access Journals (Sweden)

    Hans B Lomholt

    Full Text Available The involvement of Propionibacterium acnes in the pathogenesis of acne is controversial, mainly owing to its dominance as an inhabitant of healthy skin. This study tested the hypothesis that specific evolutionary lineages of the species are associated with acne while others are compatible with health. Phylogenetic reconstruction based on nine housekeeping genes was performed on 210 isolates of P. acnes from well-characterized patients with acne, various opportunistic infections, and from healthy carriers. Although evidence of recombination was observed, the results showed a basically clonal population structure correlated with allelic variation in the virulence genes tly and camp5, with pulsed field gel electrophoresis (PFGE- and biotype, and with expressed putative virulence factors. An unexpected geographically and temporal widespread dissemination of some clones was demonstrated. The population comprised three major divisions, one of which, including an epidemic clone, was strongly associated with moderate to severe acne while others were associated with health and opportunistic infections. This dichotomy correlated with previously observed differences in in vitro inflammation-inducing properties. Comparison of five genomes representing acne- and health-associated clones revealed multiple both cluster- and strain-specific genes that suggest major differences in ecological preferences and redefines the spectrum of disease-associated virulence factors. The results of the study indicate that particular clones of P. acnes play an etiologic role in acne while others are associated with health.

  1. Propionibacterium acnes and the Th1/Th17 Axis, implications in acne pathogenesis and treatment

    Directory of Open Access Journals (Sweden)

    Kabir Sardana

    2017-01-01

    Full Text Available Acne vulgaris is one of the most commonly seen conditions and the immunological link is a topic of active research. Recently, the Th17 pathway has been found to play a pivotal role in acne. The adaptive immune response toward Propionibacterium acnes leads to activation of Th17 axis. Consequently, the Th17 cytokines (IL-17, IL-1 β, IL-6, and tumor growth factor, in turn, activate the various pathogenic steps in acne. Drugs such as Vitamin D3 and isotretinoin which target the Th17 pathway may offer an additional pathway for their therapeutic response.

  2. Use of lipidomics to investigate sebum dysfunction in juvenile acne[S

    Science.gov (United States)

    Sinagra, Jo-Linda; Capitanio, Bruno

    2016-01-01

    Acne is a multifactorial skin disorder frequently observed during adolescence with different grades of severity. Multiple factors centering on sebum secretion are implicated in acne pathogenesis. Despite the recognized role of sebum, its compositional complexity and limited analytical approaches have hampered investigation of alterations specifically associated with acne. To examine the profiles of lipid distribution in acne sebum, 61 adolescents (29 males and 32 females) were enrolled in this study. Seventeen subjects presented no apparent clinical signs of acne. The 44 affected individuals were clinically classified as mild (13 individuals), moderate (19 individuals), and severe (12 individuals) acne. Sebum was sampled from the forehead with SebutapeTM adhesive patches. Profiles of neutral lipids were acquired with rapid-resolution reversed-phase/HPLC-TOF/MS in positive ion mode. Univariate and multivariate statistical analyses led to the identification of lipid species with significantly different levels between healthy and acne sebum. The majority of differentiating lipid species were diacylglycerols (DGs), followed by fatty acyls, sterols, and prenols. Overall, the data indicated an association between the clinical grading of acne and sebaceous lipid fingerprints and highlighted DGs as more abundant in sebum from adolescents affected with acne. PMID:27127078

  3. Diet in acne: further evidence for the role of nutrient signalling in acne pathogenesis.

    Science.gov (United States)

    Melnik, Bodo C

    2012-05-01

    Recent evidence underlines the role of Western diet in the pathogenesis of acne. Acne is absent in populations consuming Palaeolithic diets with low glycaemic load and no consumption of milk or dairy products. Two randomized controlled studies, one of which is presented in this issue of Acta Dermato-Venereologica, have provided evidence for the beneficial therapeutic effects of low glycaemic load diets in acne. Epidemiological evidence confirms that milk consumption has an acne-promoting or acne-aggravating effect. Recent progress in understanding the nutrient-sensitive kinase mammalian target of rapamycin complex 1 (mTORC1) allows a new view of nutrient signalling in acne by both high glycaemic load and increased insulin-, IGF-1-, and leucine signalling due to milk protein consumption. Acne should be regarded as an mTORC1-driven disease of civilization, like obesity, type 2 diabetes and cancer induced by Western diet. Early dietary counselling of teenage acne patients is thus a great opportunity for dermatology, which will not only help to improve acne but may reduce the long-term adverse effects of Western diet on more serious mTORC1-driven diseases of civilization.

  4. Susceptibility of Propionibacterium acnes isolated from patients with acne vulgaris to zinc ascorbate and antibiotics

    Directory of Open Access Journals (Sweden)

    Iinuma K

    2011-10-01

    Full Text Available Katsuhiro Iinuma1, Norihisa Noguchi2, Hidemasa Nakaminami2, Masanori Sasatsu2, Setsuko Nishijima3, Isami Tsuboi1 1BML General Laboratory, Matoba, Kawagoe, Saitama, 2Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, 3Department of Dermatology, Nishijima Skin Clinic, Osaka, Japan Purpose: The in vitro antimicrobial activity of ascorbic acid derivatives against Propionibacterium acnes was tested either alone or in combination with a variety of antimicrobial agents, and their fractional inhibitory concentration index was determined using checkerboard tests. The antimicrobial effectiveness of zinc ascorbate in the treatment of acne vulgaris, either alone or in combination with antibiotics such as clindamycin that are commonly used in Japan for the treatment of acne vulgaris, was therefore examined. Materials and methods: The antimicrobial susceptibility of 41 strains of clindamycin-sensitive and/or clindamycin-resistant P. acnes isolated from acne vulgaris patients was tested, in comparison with a type strain of P. acnes. Results: Zinc ascorbate showed antimicrobial activity against a type strain of P. acnes and its concentration (0.064% was sufficiently lower than the normal dose (5% of other ascorbic acid derivatives. Combinations of zinc ascorbate with clindamycin, erythromycin, and chloramphenicol showed an additive effect, and zinc ascorbate alone effectively inhibited the growth of all P. acnes including clindamycin-resistant strains. Conclusion: The results provide novel evidence that the combination of zinc ascorbate and clindamycin is effective for acne vulgaris treatment. Keywords: antimicrobial susceptibility, ascorbic acid derivatives, combination therapy, checkerboard test

  5. Papular Acne Scars of the Nose and Chin: An Under-recognised Variant of Acne Scarring.

    Science.gov (United States)

    Ali, Faisal R; Kirk, Michael; Madan, Vishal

    2016-01-01

    Scarring following acne vulgaris is common and can be of profound psychosocial consequence. We have clinically noted a variant of acne scarring, overlooked by previous categorisation schemes, which we have denominated as papular acne scars of the nose and chin. We sought to characterise these novel entities further. Initially, we identified 14 patients with papular acne scars of the nose and chin in a cosmetic dermatology clinic, of whom two were female and rest were male. We then prospectively evaluated 100 consecutive patients attending our tertiary referral acne isotretinoin clinic and 49 patients attending a general dermatology clinic. Amongst 149 patients, from a general dermatology and tertiary acne clinic, soft papular scars were noted in four patients, distributed on the nose and chin. Three of the four patients were male, three patients had additional acne scars and the median age was 23.5. We have identified 18 patients with papular acne scars of the nose and chin and propose that this new category should be added to acne scarring classification schemes. Future work should be directed at corroborating the epidemiology of such lesions and describing effective treatment modalities.

  6. Papular acne scars of the nose and chin: An under-recognised variant of acne scarring

    Directory of Open Access Journals (Sweden)

    Faisal R Ali

    2016-01-01

    Full Text Available Background: Scarring following acne vulgaris is common and can be of profound psychosocial consequence. Aims and Objectives: We have clinically noted a variant of acne scarring, overlooked by previous categorisation schemes, which we have denominated as papular acne scars of the nose and chin. We sought to characterise these novel entities further. Materials and Methods: Initially, we identified 14 patients with papular acne scars of the nose and chin in a cosmetic dermatology clinic, of whom two were female and rest were male. We then prospectively evaluated 100 consecutive patients attending our tertiary referral acne isotretinoin clinic and 49 patients attending a general dermatology clinic. Results: Amongst 149 patients, from a general dermatology and tertiary acne clinic, soft papular scars were noted in four patients, distributed on the nose and chin. Three of the four patients were male, three patients had additional acne scars and the median age was 23.5. Conclusions: We have identified 18 patients with papular acne scars of the nose and chin and propose that this new category should be added to acne scarring classification schemes. Future work should be directed at corroborating the epidemiology of such lesions and describing effective treatment modalities.

  7. Joint Design and Pricing of Intermodal Port - Hinterland Network Services: Considering Economies of Scale and Service Time Constraints

    NARCIS (Netherlands)

    P. Ypsilantis (Panagiotis); R.A. Zuidwijk (Rob)

    2013-01-01

    textabstractMaritime container terminal operating companies have extended their role from node operators to that of multimodal transport network operators. They have extended the gates of their seaport terminals to the gates of inland terminals in their network by means of frequent services of high

  8. Interim Service ISDN Satellite (ISIS) network model for advanced satellite designs and experiments

    Science.gov (United States)

    Pepin, Gerard R.; Hager, E. Paul

    1991-01-01

    The Interim Service Integrated Services Digital Network (ISDN) Satellite (ISIS) Network Model for Advanced Satellite Designs and Experiments describes a model suitable for discrete event simulations. A top-down model design uses the Advanced Communications Technology Satellite (ACTS) as its basis. The ISDN modeling abstractions are added to permit the determination and performance for the NASA Satellite Communications Research (SCAR) Program.

  9. Complementary therapies for acne vulgaris

    Science.gov (United States)

    Cao, Huijuan; Yang, Guoyan; Wang, Yuyi; Liu, Jian Ping; Smith, Caroline A; Luo, Hui; Liu, Yueming

    2015-01-01

    Background Acne is a chronic skin disease characterised by inflamed spots and blackheads on the face, neck, back, and chest. Cysts and scarring can also occur, especially in more severe disease. People with acne often turn to complementary and alternative medicine (CAM), such as herbal medicine, acupuncture, and dietary modifications, because of their concerns about the adverse effects of conventional medicines. However, evidence for CAM therapies has not been systematically assessed. Objectives To assess the effects and safety of any complementary therapies in people with acne vulgaris. Search methods We searched the following databases from inception up to 22 January 2014: the Cochrane Skin Group Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL; 2014, Issue 1), MEDLINE (from 1946), Embase (from 1974), PsycINFO (from 1806), AMED (from 1985), CINAHL (from 1981), Scopus (from 1966), and a number of other databases listed in the Methods section of the review. The Cochrane CAM Field Specialised Register was searched up to May 2014. We also searched five trials registers and checked the reference lists of articles for further references to relevant trials. Selection criteria We included parallel-group randomised controlled trials (or the first phase data of randomised cross-over trials) of any kind of CAM, compared with no treatment, placebo, or other active therapies, in people with a diagnosis of acne vulgaris. Data collection and analysis Three authors collected data from each included trial and evaluated the methodological quality independently. They resolved disagreements by discussion and, as needed, arbitration by another author. Main results We included 35 studies, with a total of 3227 participants. We evaluated the majority as having unclear risk of selection, attrition, reporting, detection, and other biases. Because of the clinical heterogeneity between trials and the incomplete data reporting, we could only include four

  10. Building Service Delivery Networks: Partnership Evolution Among Children's Behavioral Health Agencies in Response to New Funding.

    Science.gov (United States)

    Bunger, Alicia C; Doogan, Nathan J; Cao, Yiwen

    2014-12-01

    Meeting the complex needs of youth with behavioral health problems requires a coordinated network of community-based agencies. Although fiscal scarcity or retrenchment can limit coordinated services, munificence can stimulate service delivery partnerships as agencies expand programs, hire staff, and spend more time coordinating services. This study examines the 2-year evolution of referral and staff expertise sharing networks in response to substantial new funding for services within a regional network of children's mental health organizations. Quantitative network survey data were collected from directors of 22 nonprofit organizations that receive funding from a county government-based behavioral health service fund. Both referral and staff expertise sharing networks changed over time, but results of a stochastic actor-oriented model of network dynamics suggest the nature of this change varies for these networks. Agencies with higher numbers of referral and staff expertise sharing partners tend to maintain these ties and/or develop new relationships over the 2 years. Agencies tend to refer to agencies they trust, but trust was not associated with staff expertise sharing ties. However, agencies maintain or form staff expertise sharing ties with referral partners, or with organizations that provide similar services. In addition, agencies tend to reciprocate staff expertise sharing, but not referrals. Findings suggest that during periods of resource munificence and service expansion, behavioral health organizations build service delivery partnerships in complex ways that build upon prior collaborative history and coordinate services among similar types of providers. Referral partnerships can pave the way for future information sharing relationships.

  11. Psychosocial Impact of Postinflammatory Hyperpigmentation in Patients with Acne Vulgaris

    Science.gov (United States)

    Darji, Kavita; Varade, Reena; West, Daniel; Armbrecht, Eric S.

    2017-01-01

    Background: Acne vulgaris is a common, often socially distressing skin condition primarily seen in young adults. Quality of life studies have shown that people with acne are more introverted with increased social setting anxiety compared to a control group. Unfortunately, patients with acne may have residual postinflammatory hyperpigmentation, amplifying impaired psychosocial effects. Objective: To quantify the impact of postinflammatory hyperpigmentation in patients with acne using a psychometric scale. Design: A clinic-based survey was conducted among US adults with facial acne and postinflammatory hyperpigmentation. Outcomes included age, race, gender, and acne-related quality of life. A board-certified dermatologist rated each patient’s acne severity and postinflammatory hyperpigmentation. Setting: Dermatology clinic, Anheuser Busch Institute and Des Peres Hospital, Saint Louis, Missouri. Participants: 48 subjects (25 patients with acne and postinflammatory hyperpigmentation; 23 with acne only). Measurements: Acne Quality of Life survey, dermatologist rating of acne and postinflammatory hyperpigmentation severity. Results: Subjects with postinflammatory hyperpigmentation reported statistically significant poorer mean scores on the Acne Quality of Life survey than subjects with acne only. Sixty percent of patients with postinflammatory hyperpigmentation had a “very markedly” impact to at least one aspect of the Acne Quality of Life survey scale compared to none of the acne only patients. There was no association between provider-reported hyperpigmentation severity and psychosocial impact. No differences in psychosocial impact were noted between males and females. Conclusion: Patients with acne and postinflammatory hyperpigmentation had poorer quality-of-life scores compared to patients with only acne. Having postinflammatory hyperpigmentation with acne negatively impacted self-perceptions and social/emotional functioning, especially in groups. PMID

  12. The effect of mobility on local service discovery in the Ahoy ad-hoc network system

    NARCIS (Netherlands)

    Goering, P.T.H.; Heijenk, Geert; Haverkort, Boudewijn R.H.M.; Haarman, Robbert

    2007-01-01

    Ahoy, a protocol to perform local service discovery in ad-hoc networks is described in this paper. The protocol has been implemented in a discreteevent simulator to study its performance in case of a multihop mobile ad-hoc network. Especially the effect of mobility on the network load and the

  13. Provision of metro ethernet services using a reconfigurable photonic access network

    NARCIS (Netherlands)

    Roy, R.; van Etten, Wim

    2007-01-01

    The paper proposes a design for traffic engineering to provide Ethernet services using an extended access network. Ethernet has remained the dominant technology for Local Area and Enterprise Networks, the use of Ethernet in metro networks has seen significant interest of late to provide for end to

  14. User-Centric Secure Cross-Site Interaction Framework for Online Social Networking Services

    Science.gov (United States)

    Ko, Moo Nam

    2011-01-01

    Social networking service is one of major technological phenomena on Web 2.0. Hundreds of millions of users are posting message, photos, and videos on their profiles and interacting with other users, but the sharing and interaction are limited within the same social networking site. Although users can share some content on a social networking site…

  15. Spotlight on adapalene in acne vulgaris.

    Science.gov (United States)

    Waugh, John; Noble, Stuart; Scott, Lesley J

    2004-01-01

    Adapalene (Differin) is a retinoid agent indicated for the topical treatment of acne vulgaris. In clinical trials, 0.1% adapalene gel has proved to be effective in this indication and was as effective as 0.025% tretinoin gel, 0.1% tretinoin microsphere gel, 0.05% tretinoin cream and 0.1% tazarotene gel once every two days; however, the drug was less effective than once-daily 0.1% tazarotene gel. It can be used alone in mild acne or in combination with antimicrobials in inflammatory acne and has proved efficacious as maintenance treatment. Adapalene has a rapid onset of action and a particularly favorable tolerability profile compared with other retinoids. These attributes can potentially promote patient compliance, an important factor in treatment success. Adapalene is, therefore, assured of a role in the first-line treatment of acne vulgaris.

  16. Infantile acne treated with oral isotretinoin

    DEFF Research Database (Denmark)

    Miller, Iben Marie; Echeverría, Begoña; Torrelo, Antonio

    2013-01-01

    ). Consistent with the previous, limited literature, we found predominantly boys are affected, a predilection for the cheeks, and a polymorphic inflammatory morphology. Two patients had a family history of acne. All cases were successfully and safely treated with oral isotretinoin. The suggested treatment...... of childhood acne is similar to that of adolescents (graded according to the severity of the skin disease and risk of scarring). Oral isotretinoin appears to be an effective and safe treatment for severe IA.......In contrast to adolescent acne, infantile acne (IA) is a rare condition with only a limited body of available literature. In this descriptive, retrospective study, we reviewed six cases from 2002 to 2010 treated with oral isotretinoin. The average age of onset was 6.16 months (range 0-21 mos...

  17. Service for fault tolerance in the Ad Hoc Networks based on Multi Agent Systems

    Directory of Open Access Journals (Sweden)

    Ghalem Belalem

    2011-02-01

    Full Text Available The Ad hoc networks are distributed networks, self-organized and does not require infrastructure. In such network, mobile infrastructures are subject of disconnections. This situation may concern a voluntary or involuntary disconnection of nodes caused by the high mobility in the Ad hoc network. In these problems we are trying through this work to contribute to solving these problems in order to ensure continuous service by proposing our service for faults tolerance based on Multi Agent Systems (MAS, which predict a problem and decision making in relation to critical nodes. Our work contributes to study the prediction of voluntary and involuntary disconnections in the Ad hoc network; therefore we propose our service for faults tolerance that allows for effective distribution of information in the Network by selecting some objects of the network to be duplicates of information.

  18. Design Issues for Traffic Management for the ATM UBR + Service for TCP Over Satellite Networks

    Science.gov (United States)

    Jain, Raj

    1999-01-01

    This project was a comprehensive research program for developing techniques for improving the performance of Internet protocols over Asynchronous Transfer Mode (ATM) based satellite networks. Among the service categories provided by ATM networks, the most commonly used category for data traffic is the unspecified bit rate (UBR) service. UBR allows sources to send data into the network without any feedback control. The project resulted in the numerous ATM Forum contributions and papers.

  19. Acne Fulminans Treated with Oral Retinoids

    Directory of Open Access Journals (Sweden)

    Mohan B Gharpuray

    1989-01-01

    Full Text Available A 22 year old male patient suffering for 4 year from severe nodulo-cystic acne and scarring by systemic signs like fever, malaise, polyarthralgia, loss of; weight and leucocytosis was diagnosed as a case of acne fulminans. When there was no response to routine, treatment and even systemic corticosteroid, he-was treated - with a low dose of oral retinoid, isotretinoin. He improved dramatically within 2 weeks, and there was no relapse after 18 weeks follow - UP.

  20. Retinoid plus antimicrobial combination treatments for acne

    Science.gov (United States)

    Feneran, Ashley N; Kaufman, William S; Dabade, Tushar S; Feldman, Steven R

    2011-01-01

    Background: Acne vulgaris is a chronic disease with several pathogenic factors. Multiple medications are typically used that can lead to nonadherence and treatment failure. Combination medications target multiple pathways of acne formation and may offer therapeutic benefit. Purpose: To explore the efficacy and tolerability of combination retinoid plus antimicrobial treatments in acne vulgaris. Methods: A PubMed and Google search was conducted for combination therapies of clindamycin and tretinoin, with secondary analysis of related citations and references. Similar searches were completed for the combination medications of benzoyl peroxide plus clindamycin or erythromycin, and for the combination therapy of adapalene and benzoyl peroxide. Results: Combination clindamycin phosphate and tretinoin gel was found to be more efficacious than monotherapy of either drug or its vehicle for acne, including inflammatory acne, and has a greater onset of action than either drug alone. Clindamycin phosphate and tretinoin gel was well-tolerated, and adherence to its use exceeded that of using both medications in separate formulations. Benzoyl peroxide-containing combination medications with clindamycin or erythromycin were both more effective in the treatment of acne than either drug alone. Both medications were well-tolerated, with dry skin being the most common adverse effect. Conclusions: Combination medications have superior efficacy and adherence, and have a similar tolerability profile compared with monotherapy of its components. Several studies have found antibiotic-containing combination products with a retinoid effective for acne. The use of antibiotic-containing combination medications for acne can lead to bacterial resistance. Due to this potential for bacterial resistance, benzoyl peroxide treatments are also recommended in combination with a retinoid. PMID:21760743

  1. Pollution and acne: is there a link?

    Directory of Open Access Journals (Sweden)

    Krutmann J

    2017-05-01

    Full Text Available Jean Krutmann,1 Dominique Moyal,2 Wei Liu,3 Sanjiv Kandahari,4 Geun-Soo Lee,5 Noppakun Nopadon,6 Leihong Flora Xiang,7 Sophie Seité2 1IUF – Leibniz Research Institute for Environmental Medicine, Düsseldorf, Germany; 2La Roche Posay Dermatological Laboratories, Asnières, France; 3Department of Dermatology, The General Hospital of Air Force, PLA, Beijing, People’s Republic of China; 4Dr. Kandhari’s Skin & Dental Clinic, New Delhi, India; 5Drs. Woo and Hann Skin Center, Yongsan-gu, Seoul, Korea; 6Division of Dermatology, Faculty of Medicine, Department of Medicine, Chulalongkorn University, Bangkok, Thailand; 7Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, People’s Republic of China Abstract: In recent years, the critical role that inflammation may play in the development and progression of acne has become increasingly recognized. The prevalence of acne is similar between Asian and Caucasian women, but Asian women have a higher prevalence of inflammatory acne. They also report their symptoms exacerbate during periods of high air pollution. The objective of this study was to review the current evidence that links air pollution to worsening of acne symptoms. Firstly, a group of five Asian and three European scientists with expertise in Dermatology reviewed the current literature and described current acne treatment practices in their countries. During this activity, they identified the need for further epidemiological and clinical research. Secondly, additional studies ensued which provided evidence that acne symptoms might exacerbate in regions of high ambient air pollution. Based on these findings, the authors suggest that people with acne should protect the natural barrier function of their skin with emollients and ultraviolet (UVA/UVB protection. Keywords: pollution, acne, Asia, epidemiology, pathophysiology

  2. Comparative genomics and transcriptomics of Propionibacterium acnes.

    Science.gov (United States)

    Brzuszkiewicz, Elzbieta; Weiner, January; Wollherr, Antje; Thürmer, Andrea; Hüpeden, Jennifer; Lomholt, Hans B; Kilian, Mogens; Gottschalk, Gerhard; Daniel, Rolf; Mollenkopf, Hans-Joachim; Meyer, Thomas F; Brüggemann, Holger

    2011-01-01

    The anaerobic gram-positive bacterium Propionibacterium acnes is a human skin commensal that is occasionally associated with inflammatory diseases. Recent work has indicated that evolutionary distinct lineages of P. acnes play etiologic roles in disease while others are associated with maintenance of skin homeostasis. To shed light on the molecular basis for differential strain properties, we carried out genomic and transcriptomic analysis of distinct P. acnes strains. We sequenced the genome of the P. acnes strain 266, a type I-1a strain. Comparative genome analysis of strain 266 and four other P. acnes strains revealed that overall genome plasticity is relatively low; however, a number of island-like genomic regions, encoding a variety of putative virulence-associated and fitness traits differ between phylotypes, as judged from PCR analysis of a collection of P. acnes strains. Comparative transcriptome analysis of strains KPA171202 (type I-2) and 266 during exponential growth revealed inter-strain differences in gene expression of transport systems and metabolic pathways. In addition, transcript levels of genes encoding possible virulence factors such as dermatan-sulphate adhesin, polyunsaturated fatty acid isomerase, iron acquisition protein HtaA and lipase GehA were upregulated in strain 266. We investigated differential gene expression during exponential and stationary growth phases. Genes encoding components of the energy-conserving respiratory chain as well as secreted and virulence-associated factors were transcribed during the exponential phase, while the stationary growth phase was characterized by upregulation of genes involved in stress responses and amino acid metabolism. Our data highlight the genomic basis for strain diversity and identify, for the first time, the actively transcribed part of the genome, underlining the important role growth status plays in the inflammation-inducing activity of P. acnes. We argue that the disease-causing potential of

  3. Comparative genomics and transcriptomics of Propionibacterium acnes.

    Directory of Open Access Journals (Sweden)

    Elzbieta Brzuszkiewicz

    Full Text Available The anaerobic gram-positive bacterium Propionibacterium acnes is a human skin commensal that is occasionally associated with inflammatory diseases. Recent work has indicated that evolutionary distinct lineages of P. acnes play etiologic roles in disease while others are associated with maintenance of skin homeostasis. To shed light on the molecular basis for differential strain properties, we carried out genomic and transcriptomic analysis of distinct P. acnes strains. We sequenced the genome of the P. acnes strain 266, a type I-1a strain. Comparative genome analysis of strain 266 and four other P. acnes strains revealed that overall genome plasticity is relatively low; however, a number of island-like genomic regions, encoding a variety of putative virulence-associated and fitness traits differ between phylotypes, as judged from PCR analysis of a collection of P. acnes strains. Comparative transcriptome analysis of strains KPA171202 (type I-2 and 266 during exponential growth revealed inter-strain differences in gene expression of transport systems and metabolic pathways. In addition, transcript levels of genes encoding possible virulence factors such as dermatan-sulphate adhesin, polyunsaturated fatty acid isomerase, iron acquisition protein HtaA and lipase GehA were upregulated in strain 266. We investigated differential gene expression during exponential and stationary growth phases. Genes encoding components of the energy-conserving respiratory chain as well as secreted and virulence-associated factors were transcribed during the exponential phase, while the stationary growth phase was characterized by upregulation of genes involved in stress responses and amino acid metabolism. Our data highlight the genomic basis for strain diversity and identify, for the first time, the actively transcribed part of the genome, underlining the important role growth status plays in the inflammation-inducing activity of P. acnes. We argue that the disease

  4. Light-based therapies in acne treatment

    Science.gov (United States)

    Pei, Susan; Inamadar, Arun C.; Adya, Keshavmurthy A.; Tsoukas, Maria M.

    2015-01-01

    The use of light and laser in the treatment of acne is increasing as these modalities are safe, effective, and associated with no or minimal complications when used appropriately. These light and laser sources are also being used in combination with pharmacological and/or physical measures to synergize their effects and optimize the therapeutic outcome. This review focuses on optical devices used in treating acne and serves to delineate the current application of various methods, including their utility and efficacy. PMID:26009707

  5. [ACNE VULGARIS--AETIOLOGY, CLASSIFICATION, TREATMENT].

    Science.gov (United States)

    Janda, Katarzyna; Chwilkowska, Magdalena

    2014-01-01

    A spotless skin is a rarity. Both women and men have different problems related to the complexion. One of the most common problems is acne, which affects an increasing number of people of all ages. Seborrhea skin areas rich in sebaceous glands, the formation of comedones, inflammation, and scars are characteristic for this disease. The aim of the study was to discuss the causes of acne vulgaris, methods of treatment, and proper care of the skin affected by this problem.

  6. Pulse Clarithromycin Therapy In Severe ACNE Vulgaris

    Directory of Open Access Journals (Sweden)

    Rathi Sanjay K

    2002-01-01

    Full Text Available Three patients with severe acne vulgaris, not responding with long courses of doxycycline, minocycline and erythromycin were given oral clarithromycin in pulsed regimen. The patients were given 7 days course of clarithromycin 250mg twice daily, which was repeated after a gap of 10 days. Such 3 courses were given. The lesions responded significantly. No significant side effect was noted. Pulse clarithromycin therapy seems to be a good alternative and effective tool in the management of severe acne vulgaris.

  7. Multilocus sequence typing and phylogenetic analysis of Propionibacterium acnes

    DEFF Research Database (Denmark)

    Kilian, Mogens; Scholz, Christian F. P.; Lomholt, Hans B.

    2012-01-01

    Propionibacterium acnes is a commensal of human skin but is also implicated in the pathogenesis of acne vulgaris, in biofilm-associated infections of medical devices and endophthalmitis, and in infections of bone and dental root canals. Recent studies associate P. acnes with prostate cancer...... schemes were compared with reference to a phylogenetic tree based on 78 P. acnes genomes and their gene contents. Further support for a basically clonal population structure of P. acnes and a scenario of the global spread of epidemic clones of P. acnes was obtained. Compared to the Belfast scheme...

  8. Multilocus Sequence Typing (MLST) and Phylogenetic Analysis of Propionibacterium acnes

    DEFF Research Database (Denmark)

    Kilian, Mogens; Scholz, Christian; Lomholt, Hans B

    2011-01-01

    Propionibacterium acnes is a commensal of human skin but is also implicated in the pathogenesis of acne vulgaris and in biofilm-associated infections of medical devices and endophthalmitis, and in infections of bone and dental root canals. Recent studies associate P. acnes with prostate cancer...... with reference to a phylogenetic tree based on 78 P. acnes genomes and their gene contents. Further support for a basically clonal population structure of P. acnes and a scenario of global spread of epidemic clones of P. acnes was obtained. Compared with the Belfast scheme, the Aarhus MLST scheme (http...

  9. Effect of lipase activities of Propionibacterium granulosum and Propionibacterium acnes.

    Science.gov (United States)

    Higaki, S; Nakamura, M; Kitagawa, T; Morohashi, M; Yamagishi, T

    2001-01-01

    We studied the lipase activities of Propionibacterium granulosum, P. acnes and the suppression of these activities by Jumi-haidoku-to (JHT). Lipase activity of P. acnes biotype III (BIII) was strongest, while that of P. granulosum was faintly expressed. Compared with the control medium, the production of propionic and butyric acids was suppressed by all the tested mediums combined with JHT. The decrease in these acids produced by JHT was significantly higher in P. granulosum than in P. acnes. Although P. acnes BIII may produce a strong effect on acne, the presence of P. granulosum should not be ignored. Further research is required on the correlation between P. acnes and P. granulosum.

  10. Demodex mites in acne rosacea.

    Science.gov (United States)

    Roihu, T; Kariniemi, A L

    1998-11-01

    The hair follicle mites Demodex folliculorum and Demodex brevis and their role in the pathogenesis of rosacea have been the subject of much debate in the past. We studied the prevalence of Demodex mites in facial skin biopsies obtained from 80 patients with rosacea, 40 with facial eczematous eruption and 40 with lupus erythematosus discoides. The mite prevalence in the rosacea group (51%) was significantly higher than in the rest of the study population (eczema 28% and lupus discoides 31%). Demodex mites were found on all facial sites. The most infested areas in the whole study group were the forehead (49%) and the cheeks (44%). Males were more frequently infested (59%) than females (30%). We did not find any significant difference in mite counts of infested follicles between rosacea and the control group. A lympho-histiocytic cell infiltration was seen around the infested hair follicles. Our results suggest that Demodex mites may play a role in the inflammatory reaction in acne rosacea.

  11. Feasibility of a clearing house for improved cooperation between telemedicine networks delivering humanitarian services: acceptability to network coordinators

    Directory of Open Access Journals (Sweden)

    Richard Wootton

    2012-10-01

    Full Text Available Background: Telemedicine networks, which deliver humanitarian services, sometimes need to share expertise to find particular experts in other networks. It has been suggested that a mechanism for sharing expertise between networks (a ‘clearing house’ might be useful. Objective: To propose a mechanism for implementing the clearing house concept for sharing expertise, and to confirm its feasibility in terms of acceptability to the relevant networks. Design: We conducted a needs analysis among eight telemedicine networks delivering humanitarian services. A small proportion of consultations (5–10% suggested that networks may experience difficulties in finding the right specialists from within their own resources. With the assistance of key stakeholders, many of whom were network coordinators, various methods of implementing a clearing house were considered. One simple solution is to establish a central database holding information about consultants who have agreed to provide help to other networks; this database could be made available to network coordinators who need a specialist when none was available in their own network. Results: The proposed solution was examined in a desktop simulation exercise, which confirmed its feasibility and probable value. Conclusions: This analysis informs full-scale implementation of a clearing house, and an associated examination of its costs and benefits.

  12. Chemical pharmacotherapy options for managing adult acne.

    Science.gov (United States)

    Vera, Nora; Patel, Nupur; Cardwell, Leah A; Saleem, Mohammed; Feldman, Steven R

    2017-02-01

    The incidence of adult acne is increasing worldwide. Despite clinical overlap with conventional acne, it has distinct features. Areas covered: A literature search of English-language review articles, randomized control studies and retrospective studies conducted over the past 30 years was performed using PubMed and Google Scholar. Search terms included acne, adult, topical medication, oral medication and skin of color. We highlight important clinical features and treatment modalities pertinent to the evaluation and management of adult acne. Given the relative dearth of literature detailing treatment options specific to adult acne, we offer expert opinion regarding management of the condition especially in special populations such as skin of color and pregnancy. Expert Opinion: It is unclear whether adult acne represents a distinct entity or a continuum of adolescent disease. Providers may opt to use topical medication as first-line, but should have a low threshold for switching to systemic therapy given the magnitude of psychosocial and emotional burden associated with the condition.

  13. Tretinoin microsphere gel in younger acne patients.

    Science.gov (United States)

    Jorizzo, Joseph; Grossman, Rachel; Nighland, Marge

    2008-08-01

    Facial acne is common in adolescents and can have a significant psychosocial impact. Treatments prescribed should not add stress by causing excessive localized irritation. To determine whether the lowest concentration of tretinoin microsphere gel (TMG) currently available (0.04%) provides an acceptable balance of efficacy and tolerability for adolescents with moderate facial acne. The findings of 2 multicenter, randomized, double-blind, vehicle-controlled trials of TMG 0.04% applied once nightly for 12 weeks in 245 adolescents ages 11 to 16 years with moderate facial acne were combined. Patients were evaluated via changes in acne lesion counts and the occurrence of cutaneous and other adverse effects. Tretinoin microsphere gel 0.04% reduced total, noninflammatory, and inflammatory lesion counts to a significantly greater extent than the vehicle gel at 12 weeks (PTretinoin microsphere gel 0.04% was tolerated well, with over 70% of patients experiencing no cutaneous adverse events (AEs). Tretinoin microsphere gel 0.04% is effective in significantly reducing all types of acne lesions in adolescents with moderate facial acne ages 11 to 16 years, and has a low incidence of cutaneous AEs.

  14. Imaging inflammatory acne: lesion detection and tracking

    Science.gov (United States)

    Cula, Gabriela O.; Bargo, Paulo R.; Kollias, Nikiforos

    2010-02-01

    It is known that effectiveness of acne treatment increases when the lesions are detected earlier, before they could progress into mature wound-like lesions, which lead to scarring and discoloration. However, little is known about the evolution of acne from early signs until after the lesion heals. In this work we computationally characterize the evolution of inflammatory acne lesions, based on analyzing cross-polarized images that document acne-prone facial skin over time. Taking skin images over time, and being able to follow skin features in these images present serious challenges, due to change in the appearance of skin, difficulty in repositioning the subject, involuntary movement such as breathing. A computational technique for automatic detection of lesions by separating the background normal skin from the acne lesions, based on fitting Gaussian distributions to the intensity histograms, is presented. In order to track and quantify the evolution of lesions, in terms of the degree of progress or regress, we designed a study to capture facial skin images from an acne-prone young individual, followed over the course of 3 different time points. Based on the behavior of the lesions between two consecutive time points, the automatically detected lesions are classified in four categories: new lesions, resolved lesions (i.e. lesions that disappear completely), lesions that are progressing, and lesions that are regressing (i.e. lesions in the process of healing). The classification our methods achieve correlates well with visual inspection of a trained human grader.

  15. Depressive symptoms, social network, and bereavement service utilization and preferences among spouses of former hospice patients.

    Science.gov (United States)

    Bergman, Elizabeth J; Haley, William E

    2009-02-01

    Bereavement services are an important part of comprehensive end-of-life care with potential to ameliorate physical, psychological, and spiritual distress. We studied bereaved spouses of hospice patients to examine bereavement service utilization, barriers, and preferences regarding content, structure, and delivery of potential bereavement services. We also examined the impact of depressive symptoms and social network. Retrospective cohort study of bereaved spousal caregivers of patients of three hospices in Tampa Bay, Florida. Descriptive and univariate analyses assessed demographics, depressive symptoms, social network, service utilization, barriers, and preferences. Nearly half utilized at least one type of specialized professional bereavement intervention to aid in coping with their loss. The most frequently used services were provided by clergy members and physicians. Primarily attitudinal in nature, barriers included the finding that more than one third felt available services did not fit their needs or interests. Individual and spiritually-based services were highly endorsed, as were services designed to provide tools to reframe the loss and cope with accompanying changes and emotions. Lower social network was associated with higher content preferences for services consistent primarily with restoration-oriented coping. Clinicians and service providers may facilitate coping by routinely screening for depressive symptoms and social network and tailoring interventions to those identified as experiencing elevated distress or lacking social resources. Attitudinal barriers and preferences suggest that even in the service-rich environment of hospice some modification of bereavement services might reach more bereaved spouses. Future studies might address whether preferences lead individuals to services of the greatest benefit.

  16. Framework for Development of Advanced Telecommunication Services in Current and Future Converged Networks

    DEFF Research Database (Denmark)

    Soler-Lucas, José

    2006-01-01

    This thesis presents different experiences related to architectures and mechanisms for deployment of telephony services, understood as especial features complementing the basic voice service. The context for these experiences is the transition of telecommunication (telephony) networks from circuit...... been designed, implemented and tested as part of this demonstration. Performance characterization of different service implementations is also provided. Finally, a data model for an overlay network to existing telecommunication (telephony) infrastructures, allowing operational convergence is described....

  17. Designing Mobile Information Services; An approach for Organisations in a Value Network

    OpenAIRE

    Van de Kar, E.A.M.

    2004-01-01

    The mobile telecommunications industry is searching for new services, not only to recoup its investments but also to stay competitive in the future. The industry is undergoing a radical transformation and organisations in the telecommunications, information technology and media sector are becoming increasingly interdependent. Organisations have to collaborate in value networks to create new mobile information services. The challenge is to design services in these complex networks that provide...

  18. A multimodal logistics service network design with time windows and environmental concerns

    OpenAIRE

    Zhang, Dezhi; He, Runzhong; Li, Shuangyan; Wang, Zhongwei

    2017-01-01

    The design of a multimodal logistics service network with customer service time windows and environmental costs is an important and challenging issue. Accordingly, this work established a model to minimize the total cost of multimodal logistics service network design with time windows and environmental concerns. The proposed model incorporates CO2 emission costs to determine the optimal transportation mode combinations and investment selections for transfer nodes, which consider transport cos...

  19. Full Service ISDN Satellite (FSIS) network model for advanced ISDN satellite design and experiments

    Science.gov (United States)

    Pepin, Gerard R.

    1992-01-01

    The Full Service Integrated Services Digital Network (FSIS) network model for advanced satellite designs describes a model suitable for discrete event simulations. A top down model design uses the Advanced Communications Technology Satellite (ACTS) as its basis. The ACTS and the Interim Service ISDN Satellite (ISIS) perform ISDN protocol analyses and switching decisions in the terrestrial domain, whereas FSIS makes all its analyses and decisions on-board the ISDN satellite.

  20. Toll-like receptor 2 and P. acnes: do they trigger initial acne vulgaris lesions?

    Science.gov (United States)

    Bakry, Ola Ahmed; Samaka, Rehab Monir; Sebika, Hend; Seleit, Iman

    2014-04-01

    To elucidate the role of toll-like receptor 2 (TLR2) in the pathogenesis of acne vulgaris through its immunohistochemical localization in inflammatory and noninflammatory lesions of this disease entity. Using standard immunohistochemical techniques, we examined 30 acne cases (involved and noninvolved skin) and the normal skin biopsies of 30 sex- and age-matched, healthy subjects representing the control group. All examined cases showed positive TLR2 expression in epidermis, pilosebaceous units and dermal inflammatory infiltrate. There were statistically significant differences between acne-involved skin and normal skin and between acne-involved and noninvolved skin regarding TLR2 expression intensity in pilosebaceous units (p acne lesions in pilosebaceous units (p = 0.03) and dermal inflammatory infiltrate (p acne lesions in pilosebaceous units (p = 0.0002) and dermal inflammatory infiltrate (p = 0.001). TLR2 is involved in the pathogenesis of inflammatory and noninflammatory acne lesions. This occurs through Propionibacterium acnes-mediated activation with the resultant release of inflammatory cytokines.

  1. Acne e dieta: verdade ou mito? Acne and diet: truth or myth?

    Directory of Open Access Journals (Sweden)

    Adilson Costa

    2010-06-01

    Full Text Available Nos últimos 50 anos, foram publicados inúmeros estudos com a finalidade de comprovar se a dieta está relacionada à etiologia da acne. Embora existam estudos antigos, que são bem difundidos entre os dermatologistas e negam a associação entre acne e dieta, seu delineamento científico é pobre. Recentemente, novos artigos demonstraram evidências contrárias às publicações anteriores. Sendo assim, os autores realizaram esta revisão bibliográfica com o intuito de averiguar se a dieta influencia direta ou indiretamente um ou mais dos quatro pilares etiopatogênicos fundamentais da acne: (1 hiperproliferação dos queratinócitos basais, (2 aumento da produção sebácea, (3 colonização pelo Propionibacterium acnes e (4 inflamação.Numerous studies were published over the last 50 years to investigate whether diet is associated with the etiology of acne. Although older studies well known by dermatologists that refute the association between acne and diet exist, their scientific foundation is weak. New articles have recently brought to light evidence contrary to previous findings. Therefore, we would like to investigate whether diet, directly or indirectly, influences one or more of the four fundamental etiopathogenic pillars of acne: (1 hyperproliferation of basal keratinocytes, (2 increase of sebaceous production, (3 colonization by Propionibacterium acnes, and (4 inflammation.

  2. Acne

    Science.gov (United States)

    ... t Miss a Beat National Women and Girls HIV/AIDS Awareness Day National Women's Health Week Supporting Nursing Moms ... t Miss a Beat National Women and Girls HIV/AIDS Awareness Day National Women's Health Week Supporting Nursing Moms ...

  3. Acne

    Science.gov (United States)

    ... Illness & disability Drugs, alcohol & smoking Your feelings Relationships Bullying Safety Your future Environmental health Skip section navigation ( ... the level of sugar in your blood). More research is needed, but if you think your diet ...

  4. 5G-ICN : Delivering ICN Services over 5G using Network Slicing

    OpenAIRE

    Ravindran, Ravishankar; Chakraborti, Asit; Amin, Syed Obaid; Azgin, Aytac; Wang, Guoqiang

    2016-01-01

    The challenging requirements of 5G--from both the applications and the architecture perspectives--motivate the need to explore the feasibility of delivering services over new network architectures. As 5G proposes application-centric network slicing, which enables the use of new data planes realizable over a programmable compute, storage, and transport infrastructure, we consider Information-centric Networking (ICN) as a candidate network architecture to realize 5G objectives. This can co-exis...

  5. Acne vulgaris in women: prevalence across the life span.

    Science.gov (United States)

    Perkins, Alexis C; Maglione, Jessica; Hillebrand, Greg G; Miyamoto, Kukizo; Kimball, Alexa B

    2012-02-01

    Acne vulgaris is a common skin disease with a large quality of life impact, characterized by comedones, inflammatory lesions, secondary dyspigmentation, and scarring. Although traditionally considered a disease of adolescence, reports suggest it is also a disease of adults, especially adult women. Our objectives were to determine acne prevalence in a large, diverse group of women and to examine acne by subtype and in relation to other skin findings, measurements, and lifestyle factors. We recruited 2895 women aged 10-70 from the general population. Photographs were graded for acne lesions, scars, and dyspigmentation. Measurements were taken of sebum excretion and pore size, and survey data were collected. Of the women studied, 55% had some form of acne: 28% had mild acne, and 27% had clinical acne, 14% of which was primarily inflammatory and 13% of which was primarily comedonal. Acne peaked in the teenage years, but 45% of women aged 21-30, 26% aged 31-40, and 12% aged 41-50 had clinical acne. Women with inflammatory acne were younger than those with comedonal acne (p≤0.001), and postmenopausal women had less acne than age-matched peers (pAcne was associated with facial hirsutism (p=0.001), large pores (p=0.001), and sebum excretion (p=0.002). Smokers had more, primarily comedonal, acne than nonsmokers. The cross-sectional design precludes conclusions about progression of acne with age. Participation was restricted to women. The photographic nature of the study imposes general limitations. Techniques used in this study were not sufficiently sensitive to identify cases of subclinical acne. More than a quarter of women studied had acne, which peaked in the teens but continued to be prevalent through the fifth decade.

  6. Effects of fish oil supplementation on inflammatory acne

    Directory of Open Access Journals (Sweden)

    Khayef Golandam

    2012-12-01

    Full Text Available Abstract Background Given that acne is a rare condition in societies with higher consumption of omega-3 (n-3 relative to omega-6 (n-6 fatty acids, supplementation with n-3 may suppress inflammatory cytokine production and thereby reduce acne severity. Methods 13 individuals with inflammatory acne were given three grams of fish oil containing 930 mg of EPA to their unchanged diet and existing acne remedies for 12 weeks. Acne was assessed using an overall severity grading scale, total inflammatory lesion counts, and colorimetry. Findings There was no significant change in acne grading and inflammatory counts at week 12 compared to baseline. However, there was a broad range of response to the intervention on an individual basis. The results showed that acne severity improved in 8 individuals, worsened in 4, and remained unchanged in 1. Interestingly, among the individuals who showed improvement, 7 were classified as having moderate to severe acne at baseline, while 3 of the 4 whose acne deteriorated were classified as having mild acne. Conclusion There is some evidence that fish oil supplementation is associated with an improvement in overall acne severity, especially for individuals with moderate to severe acne. Divergent responses to fish oil in our pilot study indicates that dietary and supplemental lipids are worthy of further investigation in acne.

  7. A clinico-epidemiological study of adult acne: Is it different from adolescent acne?

    Directory of Open Access Journals (Sweden)

    Niti Khunger

    2012-01-01

    Full Text Available Background: Although acne is usually recognized as an adolescent skin disorder, the prevalence of adults with acne is increasing. There is surprisingly a paucity of data on the prevalence and clinical features of postadolescent acne in the adult Indian population. Aims: The clinical and epidemiological data of adult acne were evaluated with a view to establishing possible contributing etiological factors and observing whether clinical features differ from adolescent acne. Methods: Patients over the age of 25 years presenting with acne in a tertiary care hospital were included in the study. A detailed history and examination was carried out, with a stress on aggravating factors. Hormonal imbalances were investigated in females with alopecia, obesity, hirsutism and menstrual irregularity. Severity of acne and complications like scarring and psychological stress were included. Results: Out of 280 patients included in the study 82.1% were women and 17.9% were men. The mean age of the patients was 30.5 years. Persistent acne was observed in 73.2%, while it was late onset in 26.8%. Majority of the patients had inflammatory papular acne (55%, whereas comedonal acne was the least common (6%. Most common predominant site of involvement was cheek (81%, followed by chin (67%, and mandibular area (58.3%. Family history of acne was present in 38.6%. Premenstrual flare was seen in 11.7% of female patients, obesity in 6.4%, hirsutism in 5.7% and alopecia in 1.8%, but raised laboratory markers of hyperandrogenism were observed in only 3.08%. Scarring was observed in a majority of patients (76.4% and psychological stress in 52.8% patients. Conclusion: Adult acne is predominant in women, and as compared to adolescent acne is more inflammatory, with involvement of the cheeks and lower half of the face, while comedones are rare. Facial scarring occurs in a majority and stress is common, which emphasizes that adult acne should not be neglected.

  8. A Social Network Approach to Provisioning and Management of Cloud Computing Services for Enterprises

    DEFF Research Database (Denmark)

    Kuada, Eric; Olesen, Henning

    2011-01-01

    This paper proposes a social network approach to the provisioning and management of cloud computing services termed Opportunistic Cloud Computing Services (OCCS), for enterprises; and presents the research issues that need to be addressed for its implementation. We hypothesise that OCCS...... will facilitate the adoption process of cloud computing services by enterprises. OCCS deals with the concept of enterprises taking advantage of cloud computing services to meet their business needs without having to pay or paying a minimal fee for the services. The OCCS network will be modelled and implemented...... as a social network of enterprises collaborating strategically for the provisioning and consumption of cloud computing services without entering into any business agreements. We conclude that it is possible to configure current cloud service technologies and management tools for OCCS but there is a need...

  9. Unravelling Interdependence : Coordinating Public-Private Service Networks

    NARCIS (Netherlands)

    Klievink, B.

    2011-01-01

    Governments aim to improve service delivery towards citizens and businesses. One of the main trends in this area is that organisations are increasingly trying to integrate service delivery by using information and communication technology (ICT). Service integration is necessary as individual service

  10. Demo Abstract: Service Oriented Wireless Sensor Networks - A Cluster-based Approach

    NARCIS (Netherlands)

    Marin Perianu, Raluca; Scholten, Johan; Havinga, Paul J.M.

    In this paper we demonstrate a service-oriented solution for heterogeneous WSNs. The main operations are service discovery and service usage. Our solution is integrated with mobile platforms (smartphones and PDAs), that act as gateways to the GSM network and the Internet.

  11. Concept of the dealer-service network management on the system approach basis

    Directory of Open Access Journals (Sweden)

    Irina MAKAROVA

    2011-01-01

    Full Text Available In article the method of improvement of automobile service quality within the limits of a dealer-service network limits, by building of information-logistical system and feedback mechanism adjustment is considered. As operating influence application of the discounts` system calculated on the basis of forward orderings on spare parts arriving from the service centers is offered.

  12. Energy-Efficient Cluster-Based Service Discovery in Wireless Sensor Networks

    NARCIS (Netherlands)

    Marin Perianu, Raluca; Scholten, Johan; Havinga, Paul J.M.; Hartel, Pieter H.

    2006-01-01

    We propose an energy-efficient service discovery protocol for wireless sensor networks. Our solution exploits a cluster overlay, where the clusterhead nodes form a distributed service registry. A service lookup results in visiting only the clusterhead nodes. We aim for minimizing the communication

  13. Using Virtualization and Automatic Evaluation: Adapting Network Services Management Courses to the EHEA

    Science.gov (United States)

    Ros, S.; Robles-Gomez, A.; Hernandez, R.; Caminero, A. C.; Pastor, R.

    2012-01-01

    This paper outlines the adaptation of a course on the management of network services in operating systems, called NetServicesOS, to the context of the new European Higher Education Area (EHEA). NetServicesOS is a mandatory course in one of the official graduate programs in the Faculty of Computer Science at the Universidad Nacional de Educacion a…

  14. Satellites vs. fiber optics based networks and services - Road map to strategic planning

    Science.gov (United States)

    Marandi, James H. R.

    An overview of a generic telecommunications network and its components is presented, and the current developments in satellite and fiber optics technologies are discussed with an eye on the trends in industry. A baseline model is proposed, and a cost comparison of fiber- vs satellite-based networks is made. A step-by-step 'road map' to the successful strategic planning of telecommunications services and facilities is presented. This road map provides for optimization of the current and future networks and services through effective utilization of both satellites and fiber optics. The road map is then applied to different segments of the telecommunications industry and market place, to show its effectiveness for the strategic planning of executives of three types: (1) those heading telecommunications manufacturing concerns, (2) those leading communication service companies, and (3) managers of telecommunication/MIS departments of major corporations. Future networking issues, such as developments in integrated-services digital network standards and technologies, are addressed.

  15. Non-antibiotic Isotretinoin Treatment Differentially Controls Propionibacterium acnes on Skin of Acne Patients

    Directory of Open Access Journals (Sweden)

    Angela E. Ryan-Kewley

    2017-07-01

    Full Text Available Emergence and potential transfer of antibiotic resistance in skin microorganisms is of current concern in medicine especially in dermatology contexts where long term treatment with antibiotics is common. Remarkably, non-antibiotic therapy in the form of isotretinoin – a non-antimicrobial retinoid is effective at reducing or eradicating the anaerobe Propionibacterium acnes which is causally involved in the complex pathogenesis of Acne vulgaris. This study measured the extent of colonization of P. acnes in patients with primary cystic or severe acne from three defined skin sites in ‘non-lesion’ areas before, during and after treatment with isotretinoin. Patients attending acne clinics were investigated using standardized skin sampling techniques and the recovery of anaerobic P. acnes from 56 patients comprising 24 females and 32 males (mean age 22 years, age range 15–46 years who were given a standard course of isotretinoin (1 mg/kg/day are reported. P. acnes cultured from the external cheek surface of patients following treatment showed a significant reduction (1–2 orders of magnitude compared with their pre-treatment status. Interestingly, other distinct sites (nares and toe web failed to show this reduction. In addition, high levels of antibiotic-resistant P. acnes were recorded in each patients’ skin microbiota before, during and after treatment. In this study, microbial composition of the skin appears substantially altered by isotretinoin treatment, which clearly has differential antimicrobial effects on each anatomically distinct site. Our study confirmed that orally administered isotretinoin shows good efficacy in the resolution of moderate to severe acne that correlates with reductions in the number of P. acnes on the skin, including resistant isolates potentially acquired from previous treatments with antibiotics. Our study suggests that the role of tetracycline’s and macrolides, which are currently first line treatments in

  16. The photovoltaic services network: A renewable energy partnership

    Energy Technology Data Exchange (ETDEWEB)

    Plate, Peggy [Western Area Power Administration, (United states); Stokes, Kirk [NEOS Corporation, (United states)

    1995-12-31

    The Photovoltaic Services Network (PSN) is an independent organization of electric utilities established to support utility members in the use of photovoltaic (PV) power for off-grid applications. The PSN is focused on ensuring that cost-competitive, utility-grade, packaged PV products are available for various off-grid applications, such as livestock water pumping, remote residences, lighting, and cathodic protection among others. The primary objectives of the PSN are: 1) To provide education, training, and installation support as required by member utilities. 2) To establish a forum for member utilities to exchange ideas on PV program implementation and marketing strategies. 3) To create standardized system specifications for a variety of PV applications. 4) To coordinate PV product purchases for appropriate applications. 5) To identify and acquire additional funding (both publics and private) for product development and testing. 6) To pursue alliances with other organizations interested in PV. [Espanol] La Red de Servicios Fotovoltaicos (PSN) es una organizacion independiente de empresas electricas establecida para apoyar a las empresas miembro en el uso de la energia fotovoltaica en aplicaciones fuera de la red. La PSN se enfoca en garantizar que la competitividad en costo, calidad de empresa electrica de los paquetes de productos fotovoltaicos esten disponibles para varias aplicaciones fuera de la red, tales como el bombeo de agua para el ganado, residencias remotas, iluminacion y proteccion catodica entre otras. Los principales objetivos del PSN son: 1. Proporcionar educacion, entrenamiento, y apoyo en la instalacion requerida por las empresas miembro. 2. Establecer un forum de empresas miembro para intercambiar ideas sobre la puesta en practica del programa fotovoltaico y sobre la estrategias de comercializacion. 3. Crear un sistema de especificaciones estandarizadas para una variedad de aplicaciones de la energia fotovoltaica. 4. Coordinar la compra de

  17. Cross-sectional survey of awareness and behavioral pattern regarding acne and acne scar based on smartphone application.

    Science.gov (United States)

    Park, Seon Yong; Park, Mi Youn; Suh, Dae Hun; Kwon, Hyuck Hoon; Min, Seonguk; Lee, Sang Joo; Lee, Weon Ju; Lee, Mi Woo; Ahn, Hyo Hyun; Kang, Hoon; Lee, Jee Bum; Ro, Young Suck; Ahn, Kyu Joong; Kim, Myeung Nam; Kim, Kwang Joong; Kim, Nack In

    2016-06-01

    Although acne scar is a permanent sequela that may be induced by improper management of active acne lesion, patient behavior patterns and awareness regarding acne are unclear. The aim of this study was to identify awareness and behavioral patterns concerning acne and acne scar of people having acne and differences between those with and without acne scars. The survey was performed via smartphone application for 900 participants in their second to fourth decade having current or previous acne lesions. They were further categorized into two groups based on the presence of acne scar (scar and scarless groups) with no statistical difference in demographic composition. The mean age of all participants was 24.6 ± 5.3. The scar group had a longer disease duration (4.9 years) than those of the scarless group (2.2 years). Participants in the scar group thought that acne scarring affected psychosocial aspects more negatively compared with those in the scarless group. Participants in the scarless group visited dermatology clinics earlier than those in the scar group. In the scar group, 62.1% of participants have never had their acne scars treated medically. Most (88.6%) participants from both groups believed that non-dermatologic treatment caused side effects or aggravated their acne. Participants with acne scars tended to treat their acne and acne scars improperly, which could negatively affect their daily lives. Acne scars are sequelae of acne and should be regarded as a distinct disease entity, requiring a patient's early visit to dermatologic clinics. © 2015 The International Society of Dermatology.

  18. Correlation between the severity and type of acne lesions with serum zinc levels in patients with acne vulgaris.

    Science.gov (United States)

    Rostami Mogaddam, Majid; Safavi Ardabili, Nastaran; Maleki, Nasrollah; Soflaee, Maedeh

    2014-01-01

    Acne vulgaris is the most common cutaneous disorder affecting adolescents and young adults. Some studies have reported an association between serum zinc levels and acne vulgaris. We aimed to evaluate the serum zinc level in patients with acne vulgaris and compare it with healthy controls. One hundred patients with acne vulgaris and 100 healthy controls were referred to our clinic. Acne severity was classified according to Global Acne Grading System (GAGS). Atomic absorption spectrophotometry was used to measure serum zinc levels. Mean serum level of zinc in acne patients and controls was 81.31 ± 17.63 μg/dl and 82.63 ± 17.49 μg/dl, respectively. Although the mean serum zinc level was lower in acne group, it was not statistically significant (P = 0.598). There was a correlation between serum zinc levels with severity and type of acne lesions. The results of our study suggest that zinc levels may be related to the severity and type of acne lesions in patients with acne vulgaris. Relative decrease of serum zinc level in acne patients suggests a role for zinc in the pathogenesis of acne vulgaris.

  19. Correlation between the Severity and Type of Acne Lesions with Serum Zinc Levels in Patients with Acne Vulgaris

    Directory of Open Access Journals (Sweden)

    Majid Rostami Mogaddam

    2014-01-01

    Full Text Available Acne vulgaris is the most common cutaneous disorder affecting adolescents and young adults. Some studies have reported an association between serum zinc levels and acne vulgaris. We aimed to evaluate the serum zinc level in patients with acne vulgaris and compare it with healthy controls. One hundred patients with acne vulgaris and 100 healthy controls were referred to our clinic. Acne severity was classified according to Global Acne Grading System (GAGS. Atomic absorption spectrophotometry was used to measure serum zinc levels. Mean serum level of zinc in acne patients and controls was 81.31 ± 17.63 μg/dl and 82.63 ± 17.49 μg/dl, respectively. Although the mean serum zinc level was lower in acne group, it was not statistically significant (P=0.598. There was a correlation between serum zinc levels with severity and type of acne lesions. The results of our study suggest that zinc levels may be related to the severity and type of acne lesions in patients with acne vulgaris. Relative decrease of serum zinc level in acne patients suggests a role for zinc in the pathogenesis of acne vulgaris.

  20. Development of Acne therapeutic hydrogel patches by radiation technology

    Energy Technology Data Exchange (ETDEWEB)

    Lim, Younmook; Nho, Youngchang; Gwon, Huijeong; Park, Jongseok; Kim, Jinkyu; Kim, Yongsoo

    2012-04-15

    In this project, hydrogel patches containing herbal extracts mixture were developed by radiation technology for acne treatment. Propionibacterium acnes (P. acnes), one of the anaerobic bacterium, is the cause of inflammatory acne. To find novel mediation for inflammation of P. acnes, we confirmed the anti-bacterial and anti-inflammatory activities of several herbal extracts against P. acnes. The water extracts from five dried herbs, Phellodendron amurense Rupr., Paeonia lactiflora Pallas., Houttuynia cordata Thumb., Agrimonia pilosa Ledeb. and Glycyrrhiza uralensis Fisch., were mixed into biocompatible polymers and irradiated by using gamma-ray to prepare hydrogels. The hydrogels containing herbal extracts mixture initiated to decrease the growth of P. acnes and reduced the production of pro-inflammatory cytokines, TNF-{alpha}, IL-8, IL-1{beta} and IL-6, in experiment with human monocytic THP-1 cells treated with heat-killed P. acnes at 1 mg/ml of mixture concentration.

  1. Relationship between Propionibacterium acnes biotypes and Jumi-haidoku-to.

    Science.gov (United States)

    Higaki, S; Kitagawa, T; Kagoura, M; Morohashi, M; Yamagishi, T

    2000-10-01

    We examined the relationship between Propionibacterium acnes biotypes and Jumi-haidoku-to (JHT). In all the P. acnes strains tested, the production of propionic acid (PA) and butyric acid (BA) was suppressed in a medium containing 1 mg/ml JHT compared with the control medium without JHT. There were no significant differences in the rates of decreased PA and BA production between P. acnes biotype 3 (B3) and the other biotypes or between isolates from mild skin rash and more severe skin rash. P. acnes B3 was the most commonly identified biotype. The clinical effects on acne due to the anti-P. acnes lipase activity of JHT did not seem to be influenced by the degree of acne rash or the P. acnes biotype.

  2. Nanoparticle Stabilized Liposomes for Acne Therapy

    Science.gov (United States)

    Fu, Victoria

    Acne vulgaris is a common skin disease that affects over 40 million people in the United States alone. The main cause of acne vulgaris is Propionibacterium acnes (P. acnes), resides deep in the pores and follicles of the skin in order to feed on oil produced by the sebaceous glands. The liposome is a lipid based nanoparticle with numerous advantages over free drug molecules as an acne treatment alternative. Bare liposomes loaded with lauric acid (LipoLA) were found to show strong antimicrobial activity against P. acnes while generating minimal toxicity. However, the platform is limited by the spontaneous tendency of liposomes to fuse with each other. Attaching nanoparticles to the surface of liposomes can overcome this challenge by providing steric repulsion and reduce surface tension. Thus, carboxyl-functionalized gold nanoparticles (AuC) were attached to the surface of liposomes (AuC-liposomes) loaded with doxycycline, a general tetracycline antibiotic. These particles were found to have a diameter of 120 nm and a zeta potential of 20.0 mV. Both fluorescent and antimicrobial studies demonstrated that based on electrostatic interaction, negatively charged AuC attached to the liposome's positively charged surface and stabilized liposomes in a neutral pH environment (pH = 7.4). Upon entering the skin's acidic environment (pH = 4), AuC detached from the liposome's surface and liposomes could fuse with P. acnes residing in the pores. Furthermore, toxicity studies showed that AuC-liposomes did not induce any significant toxicity, while two of the leading over-the-counter therapies, benzoyl peroxide and salicylic acid, generated substantial skin irritation.

  3. Building Rural Surgical Networks: An Evidence-Based Approach to Service Delivery and Evaluation.

    Science.gov (United States)

    Kornelsen, Jude; Friesen, Randy

    2016-08-01

    Formalized rural health service delivery networks are emerging as an over-arching response to the attrition of rural surgical and maternity services in Canada. In effective networks, there is strong collaborative leadership, form follows function, core network elements are identified and site-specific variations are accommodated to meet the surgical needs of the population in each geographic catchment. The network catchment must reflect the natural alliances that already exist among health professionals, policy makers, health administrators, academic institutions and communities. Although each key stakeholder plays a key role in determining success, value is added through the synergistic interplay of all participants. Copyright © 2016 Longwoods Publishing.

  4. Network-Based Coordination of Civil-Service Training: Lessons from the Case of Estonia

    Directory of Open Access Journals (Sweden)

    Metsma Merilin

    2017-06-01

    Full Text Available The focus of this article is on the coordination of civil-service training in a decentralized civil-service system. The Estonian case is studied. The article investigates network-based coordination, analyzes the power sources of the central coordinator and discusses the opportunities and limitations of creating coherence through network-type cooperation. The article concludes that the key power sources for the central coordinator are financial, human and technical resources paired with knowledge, leadership and commitment. The case study shows that, in a decentralized civil service system, a common understanding on training and development can be fostered by intense collaboration through networks.

  5. 78 FR 47778 - Verizon Business Networks Services, Inc. Senior Analysts-Sales Impletmentation (SA-SI) Birmingham...

    Science.gov (United States)

    2013-08-06

    ... Employment and Training Administration Verizon Business Networks Services, Inc. Senior Analysts-Sales Impletmentation (SA-SI) Birmingham, Alabama; Verizon Business Networks Services, Inc. Senior Analysts-Sales Impletmentation (SA-SI) Service Program Delivery Division San Francisco, California; Verizon Business Networks...

  6. WEB 2.0 SERVICES AS A TECHNOLOGICAL FOUNDATION OF A NETWORK PROJECT

    Directory of Open Access Journals (Sweden)

    Tatiana Ivanovna Kanyanina

    2015-02-01

    Full Text Available In the light of the requirements of the federal state educational standard increases the value of the network design based on the use of Web 2.0 services. The article outlines the range of technological challenges faced by the developer of the network project, such as the choice of the network platform of the project, design tools and tools for project results placement, project coordination and organization of communication lines, the choice of instruments for the promotion of the project on the Internet. The main attention is focused on the examples of network services that address these challenges, and describe their features. The authors rely on the specific network projects implemented in Nizhny Novgorod region. The paper analyzes the possible project’s network sites (network environment. The article gives a general description of each environment, marks its distinctive features, advantages and disadvantages. The article presents project tasks’ examples, designed on the basis of the variety of Web 2.0 services that functionally meet the requirements of a particular task, examples of services to represent the project products and to summarize its results. Attention is paid to the organization of the lines of communication of the project participants and organizers and to the role of network services in the project promotion on the Internet.

  7. Trunk Reservation in Multi-service Networks with BPP Traffic

    DEFF Research Database (Denmark)

    Zheng, H.; Zhang, Qi; Iversen, Villy Bæk

    2006-01-01

    algorithm which allows for calculation of individual performance measures for each service, in particular the traffic congestion. The algorithm is numerically robust and requires a minimum of computer memory and computing time. The approximation is good when the services have equal mean service times....

  8. Mobile location services for the next generation wireless network

    DEFF Research Database (Denmark)

    Schou, Saowanee

    2008-01-01

    of interest, getting weather information, and tracking the whereabouts of a child. Mobile location services gained a great deal of interest in 2000, and they were envisioned by the business players in the mobile service market as one of the few service categories where the mobile users would be willing to pay...

  9. Antimicrobial effects of Indian medicinal plants against acne ...

    African Journals Online (AJOL)

    Propionibacterium acnes and Staphylococcus epidermidis have been recognized as pus-forming bacteria triggering an inflammation in acne. The present study was conducted to evaluate antimicrobial activities of Indian medicinal plants against these etiologic agents of acne vulgaris. Ethanolic extracts of Hemidesmus ...

  10. acne vulgaris. grades of severity and treatment options

    African Journals Online (AJOL)

    Acne is the most common skin condition treated by dermatologists. Acne is a polymorphic disease exhibiting a number of diverse lesions: comedones, papules, pustules, nodules, cysts, sinuses and scars. Despite this diversity, acne can be reduced to a two'stage sequence of events. Firstly an abnormal hypercornification ...

  11. 21 CFR 333.310 - Acne active ingredients.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 5 2010-04-01 2010-04-01 false Acne active ingredients. 333.310 Section 333.310... FOR HUMAN USE TOPICAL ANTIMICROBIAL DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Topical Acne Drug Products § 333.310 Acne active ingredients. The active ingredient of the product consists of any of the...

  12. Assessing Network Services and Security in Nigeria Universities ...

    African Journals Online (AJOL)

    Journal of Computer Science and Its Application ... The paper investigated sources of threats and vulnerabilities to Nigerian university computer networks and assessed the adequacy of security controls in place to ... This was with a view to enhancing the integrity of data transactions on the Universities' computer networks.

  13. Social networks as the context for understanding employment services utilization among homeless youth.

    Science.gov (United States)

    Barman-Adhikari, Anamika; Rice, Eric

    2014-08-01

    Little is known about the factors associated with use of employment services among homeless youth. Social network characteristics have been known to be influential in motivating people's decision to seek services. Traditional theoretical frameworks applied to studies of service use emphasize individual factors over social contexts and interactions. Using key social network, social capital, and social influence theories, this paper developed an integrated theoretical framework that capture the social network processes that act as barriers or facilitators of use of employment services by homeless youth, and understand empirically, the salience of each of these constructs in influencing the use of employment services among homeless youth. We used the "Event based-approach" strategy to recruit a sample of 136 homeless youth at one drop-in agency serving homeless youth in Los Angeles, California in 2008. The participants were queried regarding their individual and network characteristics. Data were entered into NetDraw 2.090 and the spring embedder routine was used to generate the network visualizations. Logistic regression was used to assess the influence of the network characteristics on use of employment services. The study findings suggest that social capital is more significant in understanding why homeless youth use employment services, relative to network structure and network influence. In particular, bonding and bridging social capital were found to have differential effects on use of employment services among this population. The results from this study provide specific directions for interventions aimed to increase use of employment services among homeless youth. Copyright © 2014 Elsevier Ltd. All rights reserved.

  14. A Social Network Approach to Provisioning and Management of Cloud Computing Services for Enterprises

    OpenAIRE

    Kuada, Eric; Olesen, Henning

    2011-01-01

    This paper proposes a social network approach to the provisioning and management of cloud computing services termed Opportunistic Cloud Computing Services (OCCS), for enterprises; and presents the research issues that need to be addressed for its implementation. We hypothesise that OCCS will facilitate the adoption process of cloud computing services by enterprises. OCCS deals with the concept of enterprises taking advantage of cloud computing services to meet their business needs without hav...

  15. Applying ADLs to Assess Emerging Industry Specifications for Dynamic Discovery of Ad Hoc Network Services

    Science.gov (United States)

    2001-01-31

    0..1 Contains 1 Contains SERVICE MANAGER discov er Network Context() <<not shr>> Cache Manager Discov ery () <<OPT>> Announce Serv ice Processing...Architectural Layers Approach JINI Entities Service Manager Entity Major Functions Lazy Discovery Directed Discovery Client (s,ra) Aggressive...registered-services SCM SM discovered-SCMs (SU NR SCM): (SU,NR) SCM registered-notifications SCM SU discovered-SCMs • SM is Service Manager • SD is

  16. Low-Power Wireless Sensor Networks Protocols, Services and Applications

    CERN Document Server

    Suhonen, Jukka; Kaseva, Ville; Hämäläinen, Timo D; Hännikäinen, Marko

    2012-01-01

    Wireless sensor network (WSN) is an ad-hoc network technology comprising even thousands of autonomic and self-organizing nodes that combine environmental sensing, data processing, and wireless networking. The applications for sensor networks range from home and industrial environments to military uses. Unlike the traditional computer networks, a WSN is application-oriented and deployed for a specific task. WSNs are data centric, which means that messages are not send to individual nodes but to geographical locations or regions based on the data content. A WSN node is typically battery powered and characterized by extremely small size and low cost. As a result, the processing power, memory, and energy resources of an individual sensor node are limited. However, the feasibility of a WSN lies on the collaboration between the nodes. A reference WSN node comprises a Micro-Controller Unit (MCU) having few Million Instructions Per Second (MIPS) processing speed, tens of kilobytes program memory, few kilobytes data m...

  17. Photodynamic-induced inactivation of Propionibacterium acnes

    Science.gov (United States)

    Koenig, Karsten; Teschke, M.; Eick, Stephen G.; Pfister, W.; Meyer, Herbert; Halbhuber, Karl-Juergen

    1998-05-01

    We report on photodynamically induced inactivation of the skin bacterium Propionibacterium acnes (P. acnes) using endogenous as well as exogenous photosensitizers and red light sources. P. acnes is involved in the pathogenesis of the skin disease acne vulgaris. The skin bacterium is able to synthesize the metal-free fluorescent porphyrins protoporphyrin IX (PP) and coproporphyrin (CP) as shown by in situ spectrally-resolved detection of natural autofluorescence of human skin and bacteria colonies. These naturally occurring intracellular porphyrins act as efficient endogenous photosensitizers. Inactivation of P. acnes suspensions was achieved by irradiation with He-Ne laser light in the red spectral region (632.8 nm). We monitored the photodynamically-induced death of single bacteria using a fluorescent viability kit in combination with confocal laser scanning microscopy. In addition, the photo-induced inactivation was calculated by CFU (colony forming units) determination. We found 633 nm-induced inactivation (60 mW, 0.12 cm2 exposure area, 1 hour irradiation) of 72% in the case of non-incubated bacteria based on the destructive effect of singlet oxygen produced by red light excited endogenous porphyrins and subsequent energy transfer to molecular oxygen. In order to achieve a nearly complete inactivation within one exposure procedure, the exogenous photosensitizer Methylene Blue (Mb) was added. Far red exposure of Mb-labeled bacteria using a krypton ion laser at 647 nm and 676 nm resulted in 99% inactivation.

  18. Treatment of acne vulgaris in pregnant patients.

    Science.gov (United States)

    Pugashetti, Rupa; Shinkai, Kanade

    2013-01-01

    The management of acne vulgaris in the setting of pregnancy raises important clinical considerations regarding the efficacy and safety of acne treatments in this special patient population. Particular challenges include the absence of safety data, discrepancy in safety data between different safety rating systems, and lack of evidence-based recommendations for the treatment of acne during pregnancy. Nonetheless, many therapeutic options exist, and the treatment of acne in pregnant women can be safely and often effectively accomplished. For mild or moderate disease, patients can be treated with topical antimicrobial agents, anti-inflammatory agents, as well as glycolic and salicylic acid. Several topical agents, notably benzoyl peroxide, previously viewed as potentially dangerous are cited by many sources as being considered safe. When necessary, systemic therapies that can be safely added include penicillins, amoxicillin, cephalosporins, erythromycin, clindamycin, and tetracyclines or sulfonamides, depending on the stage of fetal development. Adjunct therapy may include phototherapy or laser treatments. Physicians should work with this often highly motivated, safety-conscious patient population to tailor an individualized treatment regimen. This treatment regimen will likely shift throughout the different stages of fetal development, as distinct safety considerations are raised prior to conception as well as during each of the trimesters of pregnancy. Important considerations regarding acne management in breast-feeding mothers is also discussed. © 2013 Wiley Periodicals, Inc.

  19. Emerging Issues in Adult Female Acne

    Science.gov (United States)

    Baldwin, Hillary E.; Cook-Bolden, Fran E.; Eichenfield, Lawrence F.; Friedlander, Sheila F.; Rodriguez, David A.

    2017-01-01

    Acne vulgaris (acne) is a common affliction in adolescence and is a growing problem in adult women. Despite an increasing awareness of acne in the adult female population, there is a lack of good prospective studies assessing the severity, distribution, and differential response to treatment in this group. The long-held dogma that acne in adult women develops on the lower one-third of the face has been recently challenged, and here the authors critically review data from available literature. Moreover, while adult female acne has traditionally been defined as disease in women over age 25, it is the authors’ experience that this group is subdivided into women ages 25 to 44 years, separate from perimenopausal patients, ages 45 years and up. While there is no data specifically comparing these two groups, the authors will review the existing data and provide practical recommendations based on our experience in treating these groups of patients. Finally, while there is a lack of data on this subject, it is the group’s opinion that adherence to medication regimens is likely higher in women than men, which influences therapeutic outcomes. PMID:28210380

  20. Isotretinoin, tetracycline and circulating hormones in acne.

    Science.gov (United States)

    Palatsi, R; Ruokonen, A; Oikarinen, A

    1997-09-01

    Isotretinoin, used to treat severe acne, has been shown to induce hormonal changes, especially to reduce 5 alpha-reductase in the production of the tissue-derived dihydrotestosterone (DHT) metabolite 3 alpha-Adiol G. However, the effects of isotretinoin on other pituitary, adrenal or gonadal hormones have not been thoroughly elucidated. In the present study, isotretinoin administered at a dose of 0.5 mg/kg/day for 4 weeks caused no marked changes in the serum levels of pituitary, adrenal or gonadal hormones or 3 alpha-Adiol G in patients with severe papulopustulotic acne (n = 19). After 12 weeks of therapy, there was a decrease in the levels of the precursor androgens androstenedione, testosterone and 3 alpha-Adiol G in 6/9 patients. Acne improved after 4.5 months in all but 2 male patients, who had very low serum hormone binding globulins (SHBG) and a high free androgen index (FAI). Isotretinoin did not affect the elevated LH/FSH ratio in a patient with the polycystic ovarian syndrome (PCOS); nor did it change the high FAI or low SHBG in the male patients. For comparison, tetracycline had no effects on the serum hormonal levels of patients with mild acne (n = 19) after 7 days of treatment. This study confirms that the effects of isotretinoin on the serum hormone levels are small and unlikely to be of relevance for the resolution of acne or the suppression of sebum excretion.

  1. New insights into acne pathogenesis: Exploring the role of acne-associated microbial populations

    Directory of Open Access Journals (Sweden)

    Bipul Kumar

    2016-06-01

    Full Text Available Acne vulgaris, a prevalent disorder of the skin, is found to increase the incidence of suicidal ideation in acne patients (∼7.1%. This creates a dilemma in the mind whether acne is a life threatening disease among humans. The main inducer for this multifactorial disease is microbial fluctuation of common resident microbes on the skin with each microbe possessing their own purpose and style in protecting the human body. For acne progression, the microbial population has to get around the defense barriers of the host skin and be able to also resist them in order to survive. These matters have been resolved by their pathogenic lifecycle and associated virulence factors coded within their pathogenic islands in the single circular chromosome. This review addresses the different microbial populations residing in acne lesions and promoting acne by emphasizing their pathogenic mechanisms and the genes associated with virulence factors involved in the development of acne. Model systems such as animal models and cell culture models in studying the pathogenic lifestyle of the microbes are also addressed.

  2. Subjective Evaluation of Packet Service Performance in UMTS and Heterogeneous Networks

    DEFF Research Database (Denmark)

    Teyeb, Oumer Mohammed; Sørensen, Troels Bundgaard; Mogensen, Preben

    2006-01-01

    Quality of Service (QoS) in mobile telecommunication systems is usually identified by some basic performance metrics such as delay, throughput and jitter. However, the main impact of service quality is on the end user, and as such a detailed study of service performance should involve the end user....... In this paper, such an approach is taken where subjective performance evaluation is undertaken for web browsing and video streaming services in Universal Mobile Telecommunication System (UMTS) and a heterogeneous network comprised of UMTS and Wireless LAN (WLAN). Using a real-time network emulation testbed...

  3. Model establishing and performance analysis of service stratum traffic in the integrated sensing network

    Science.gov (United States)

    Ge, Zhiqun; Wang, Ying; Zhang, Xiaolu; Zheng, Yu; Zhao, Xinqun; Sun, Xiaohan

    2017-01-01

    We propose a time-division hybrid-user data flow model scheme based on semi-Markov state-transition algorithm for multiclass business and service in Integrated Sensing Network (ISN). Two typical flow models, visual sense and auditory sense service models, are set up due to the real situation of service stratum traffic, respectively. The experimental system based on the Asynchronous Optical Packet Switching (AOPS) network simulation platform is established for the feasibility of the proposed data flow model. The results show that the proposed models achieve reasonable packet loss rate and delay time in the case of different business and service levels.

  4. Analysis of Blocking Rate and Bandwidth Usage of Mobile IPTV Services in Wireless Cellular Networks

    Directory of Open Access Journals (Sweden)

    Mingfu Li

    2014-01-01

    Full Text Available Mobile IPTV services over wireless cellular networks become more and more popular, owing to the significant growth in access bandwidth of wireless cellular networks such as 3G/4G and WiMAX. However, the spectrum resources of wireless cellular networks is rare. How to enhance the spectral efficiency of mobile networks becomes an important issue. Unicast, broadcast, and multicast are the most important transport schemes for offering mobile IPTV services over wireless cellular networks. Therefore, bandwidth usages and blocking rates of unicast, broadcast, and multicast IPTV services were analyzed and compared in this paper. Simulations were also conducted to validate the analytical results. Numerical results demonstrate that the presented analysis is correct, and multicast scheme achieves the best bandwidth usage and blocking rate performance, relative to the other two schemes.

  5. Analysis of blocking rate and bandwidth usage of mobile IPTV services in wireless cellular networks.

    Science.gov (United States)

    Li, Mingfu

    2014-01-01

    Mobile IPTV services over wireless cellular networks become more and more popular, owing to the significant growth in access bandwidth of wireless cellular networks such as 3G/4G and WiMAX. However, the spectrum resources of wireless cellular networks is rare. How to enhance the spectral efficiency of mobile networks becomes an important issue. Unicast, broadcast, and multicast are the most important transport schemes for offering mobile IPTV services over wireless cellular networks. Therefore, bandwidth usages and blocking rates of unicast, broadcast, and multicast IPTV services were analyzed and compared in this paper. Simulations were also conducted to validate the analytical results. Numerical results demonstrate that the presented analysis is correct, and multicast scheme achieves the best bandwidth usage and blocking rate performance, relative to the other two schemes.

  6. Time Shared Optical Network (TSON): a novel metro architecture for flexible multi-granular services.

    Science.gov (United States)

    Zervas, Georgios S; Triay, Joan; Amaya, Norberto; Qin, Yixuan; Cervelló-Pastor, Cristina; Simeonidou, Dimitra

    2011-12-12

    This paper presents the Time Shared Optical Network (TSON) as metro mesh network architecture for guaranteed, statistically-multiplexed services. TSON proposes a flexible and tunable time-wavelength assignment along with one-way tree-based reservation and node architecture. It delivers guaranteed sub-wavelength and multi-granular network services without wavelength conversion, time-slice interchange and optical buffering. Simulation results demonstrate high network utilization, fast service delivery, and low end-to-end delay on a contention-free sub-wavelength optical transport network. In addition, implementation complexity in terms of Layer 2 aggregation, grooming and optical switching has been evaluated. © 2011 Optical Society of America

  7. Multi-Service Group Key Management for High Speed Wireless Mobile Multicast Networks

    Directory of Open Access Journals (Sweden)

    Trust T. Mapoka

    2015-08-01

    Full Text Available Recently there is a high demand from the Internet Service Providers to transmit multimedia services over high speed wireless networks. These networks are characterized by high mobility receivers which perform frequent handoffs across homogenous and heterogeneous access networks while maintaining seamless connectivity to the multimedia services. In order to ensure secure delivery of multimedia services to legitimate group members, the conventional cluster based group key management (GKM schemes for securing group communication over wireless mobile multicast networks have been proposed. However, they lack efficiency in rekeying the group key in the presence of high mobility users which concurrently subscribe to multiple multicast services that co-exist in the same network. This paper proposes an efficient multi-service group key management scheme (SMGKM suitable for high mobility users which perform frequent handoffs while participating seamlessly in multiple multicast services. The users are expected to drop subscriptions after multiple cluster visits hence inducing huge key management overhead due to rekeying the previously visited cluster keys. The already proposed multi-service SMGKM system with completely decentralised authentication and key management functions is adopted to meet the demands for high mobility environment with the same level of security. Through comparisons with existing GKM schemes and simulations, SMGKM shows resource economy in terms of reduced communication and less storage overheads in a high speed environment with multiple visits.

  8. Towards a Framework for Self-Adaptive Reliable Network Services in Highly-Uncertain Environments

    DEFF Research Database (Denmark)

    Grønbæk, Lars Jesper; Schwefel, Hans-Peter; Ceccarelli, Andrea

    2010-01-01

    to improve resilience of end-node services. In this paper we present a framework, called ODDR (Observation, Diagnosis, Decision, Remediation), for improving resilience of network based services through integration of self-adaptive monitoring services, network diagnosis, decision actions, and finally......In future inhomogeneous, pervasive and highly dynamic networks, end-nodes may often only rely on unreliable and uncertain observations to diagnose hidden network states and decide upon possible remediation actions. Inherent challenges exists to identify good and timely decision strategies...... execution (and monitoring) of remediation actions. We detail the motivations to the ODDR design, then we present its architecture, and finally we describe our current activities towards the realization and assessment of the framework services and the main results currently achieved....

  9. Social network as a determinant of pathway to mental health service ...

    African Journals Online (AJOL)

    14,15] and the perceived or actual reactions of ... of perceived support. Both network and support can act as coping resources.[20,21] While some ..... disability and service utilisation. Overview of the. Australian National Mental Health Survey.

  10. Optimal Incentive Pricing on Relaying Services for Maximizing Connection Availability in Multihop Cellular Networks

    Directory of Open Access Journals (Sweden)

    Ming-Hua Lin

    2012-01-01

    Full Text Available This paper investigates an incentive pricing problem for relaying services in multihop cellular networks. Providing incentives to encourage mobile nodes to relay data is a critical factor in building successful multihop cellular networks. Most existing approaches adopt fixed-rate or location-based pricing on rewarding packets forwarding. This study applies a mathematical programming model to determine an optimal incentive price for each intermediate node that provides relaying services. Under the obtained incentive price, the connection availability of the networks is maximized by using the same relaying costs as other pricing schemes. A signomial geometric programming problem is constructed, and a deterministic optimization approach is employed to solve the problem. Besides, quality-of-service constraints are added in the proposed model to mitigate the unfairness between connection availabilities of individual nodes. Computational results demonstrate that the proposed model obtains the optimal incentive price on relaying services to maximize connection availability of the networks.

  11. Dynamic baseline detection method for power data network service

    Science.gov (United States)

    Chen, Wei

    2017-08-01

    This paper proposes a dynamic baseline Traffic detection Method which is based on the historical traffic data for the Power data network. The method uses Cisco's NetFlow acquisition tool to collect the original historical traffic data from network element at fixed intervals. This method uses three dimensions information including the communication port, time, traffic (number of bytes or number of packets) t. By filtering, removing the deviation value, calculating the dynamic baseline value, comparing the actual value with the baseline value, the method can detect whether the current network traffic is abnormal.

  12. Collaborative Tools for e-Participation across Networks: The Comuno Networking Site for Public Governance and Services

    Directory of Open Access Journals (Sweden)

    Michael Kaschesky

    2010-04-01

    Full Text Available This paper presents collaborative tools for public participation across multiple networking sites. The tools are part of the Comuno networking site for public governance and services, which is particularly targeted at the public sector (currently in alpha testing at http://comuno.org. The Broadcast tool allows cross-posting content from Comuno to a wide variety of other networking sites, such as Facebook or Twitter. The UserFeed and TopicFeed tools build RSS feeds from content published by a specific user or under a specific topic. The LifeStream tool gathers a user’s activities across multiple networking sites in the private account section at Comuno. These tools and related aspects of the Comuno networking site are discussed and presented in the context of deliberation and opinion-forming in a Swiss bilingual city.

  13. Managing cancer care through service delivery networks: The role of professional collaboration in two European cancer networks.

    Science.gov (United States)

    Prades, Joan; Morando, Verdiana; Tozzi, Valeria D; Verhoeven, Didier; Germà, Jose R; Borras, Josep M

    2017-01-01

    Background The study examines two meso-strategic cancer networks, exploring to what extent collaboration can strengthen or hamper network effectiveness. Unlike macro-strategic networks, meso-strategic networks have no hierarchical governance structures nor are they institutionalised within healthcare services' delivery systems. This study aims to analyse the models of professional cooperation and the tools developed for managing clinical practice within two meso-strategic, European cancer networks. Methods Multiple case study design based on the comparative analysis of two cancer networks: Iridium, in Antwerp, Belgium and the Institut Català d'Oncologia in Catalonia, Spain. The case studies applied mixed methods, with qualitative research based on semi-structured interviews ( n = 35) together with case-site observation and material collection. Results The analysis identified four levels of collaborative intensity within medical specialties as well as in multidisciplinary settings, which became both platforms for crosscutting clinical work between hubs' experts and local care teams and the levers for network-based tools development. The organisation of clinical practice relied on professional-based cooperative processes and tiers, lacking vertical integration mechanisms. Conclusions The intensity of professional linkages largely shaped the potential of meso-strategic cancer networks to influence clinical practice organisation. Conversely, the introduction of managerial techniques or network governance structures, without introducing vertical hierarchies, was found to be critical solutions.

  14. Integration of service, network and system management: current and forthcoming trends

    OpenAIRE

    Oliveira, José Luís; Aguiar, Rui; Lopes, Rui Pedro

    2000-01-01

    A major problem that industry is being faced with is related to the miscellaneous of management requirements and to the explosion of management information. Network and systems management often make use of different tools and technologies. The introduction of Quality of Service in the Internet will bring increased needs for efficient service management approaches in the network. The integration of these different kinds of management approaches into a common framewor...

  15. Generic Traffic Descriptors in Managing Service Quality in BISDN/ATM Network

    Directory of Open Access Journals (Sweden)

    Ivan Bošnjak

    2002-03-01

    Full Text Available Traffic models for multiservice broadband networks differsignificantly regarding simple analytic models applicable intelephone traffic and circuit-switch network. The paper presentsa clear analysis of standardised traffic descriptors andquality parameters of the main services in BISDNIATM. Trafficdescriptors have been associated with the basic values andconcepts developed within generic traffic theory. Part systematisationof traffic parameters has been performed as basis for formalisedgeneralised description of parameters and effectivequality management of A TM services.

  16. Discovery and Protection of Sensitive Linkage Information for Online Social Networks Services

    Science.gov (United States)

    Zhang, Nan; Song, Min; Fu, Xinwen; Yu, Wei

    This paper investigates the problem of suppressing access to sensitive linkage information over data published by users of an online social network service. We unveil the potential threats by inferring linkage information from the user-published data, and suggest a class of data publishing schemes to enable distributed data publication by individual users but hide the sensitive information. Our hope is that this white paper shed lights on the future investigation of privacy-preserving online social network services.

  17. Algorithm Design for Assignment Frequency Channels for Services in CATV Network

    Directory of Open Access Journals (Sweden)

    Jan Hlubik

    2008-01-01

    Full Text Available This article describes algorithm design for assignment frequency channels for services in CATV network. QAM modulated channels in designed system are dynamically switched and frequency adapted. On introduction, there is shortly described principle of providing analog video, digital video and data services in CATV network. Object of the article is focused on method of allocation individual TV and data channels on the frequency band. The conclusion compares advantages and disadvantages present and design system.

  18. What is 5G? Emerging 5G Mobile Services and Network Requirements

    Directory of Open Access Journals (Sweden)

    Heejung Yu

    2017-10-01

    Full Text Available In this paper, emerging 5G mobile services are investigated and categorized from the perspective of not service providers, but end-users. The development of 5G mobile services is based on an intensive analysis of the global trends in mobile services. Additionally, several indispensable service requirements, essential for realizing service scenarios presented, are described. To illustrate the changes in societies and in daily life in the 5G era, five megatrends, including the explosion of mobile data traffic, the rapid increase in connected devices, everything on the cloud, hyper-realistic media for convergence services and knowledge as a service enabled by big-data analysis, are examined. Based on such trends, we classify the new 5G services into five categories in terms of the end-users’ experience as follows: immersive 5G services, intelligent 5G services, omnipresent 5G services, autonomous 5G services and public 5G services. Moreover, several 5G service scenarios in each service category are presented, and essential technical requirements for realizing the aforementioned 5G services are suggested, along with a competitiveness analysis on 5G services/devices/network industries and the current condition of 5G technologies.

  19. Trace saver: A tool for network service improvement and personalised analysis of user centric statistics

    Science.gov (United States)

    Bilal, Muhammad; Asfand-e-Yar, Mockford, Steve; Khan, Wasiq; Awan, Irfan

    2012-11-01

    Mobile technology is among the fastest growing technologies in today's world with low cost and highly effective benefits. Most important and entertaining areas in mobile technology development and usage are location based services, user friendly networked applications and gaming applications. However, concern towards network operator service provision and improvement has been very low. The portable applications available for a range of mobile operating systems which help improve the network operator services are desirable by the mobile operators. This paper proposes a state of the art mobile application Tracesaver, which provides a great achievement over the barriers in gathering device and network related information, for network operators to improve their network service provision. Tracesaver is available for a broad range of mobile devices with different mobile operating systems and computational capabilities. The availability of Tracesaver in market has proliferated over the last year since it was published. The survey and results show that Tracesaver is being used by millions of mobile users and provides novel ways of network service improvement with its highly user friendly interface.

  20. Multipath protection for data center services in OpenFlow-based software defined elastic optical networks

    Science.gov (United States)

    Yang, Hui; Cheng, Lei; Yuan, Jian; Zhang, Jie; Zhao, Yongli; Lee, Young

    2015-06-01

    With the rapid growth of data center services, the elastic optical network is a very promising networking architecture to interconnect data centers because it can elastically allocate spectrum tailored for various bandwidth requirements. In case of a link failure, to ensure a high-level quality of service (QoS) for user request after the failure becomes a research focus. In light of it, in this paper, we propose and experimentally demonstrate multipath protection for data center services in OpenFlow-based software defined elastic optical network testbed aiming at improving network reliability. We first propose an OpenFlow-based software defined elastic optical network architecture for data center service protection. Then, based on the proposed architecture, multipath protection scheme is figured based on the importance level of the service. To implement the proposed scheme in the architecture, OpenFlow protocol is extended to support multipath protection in elastic optical network. The performance of our proposed multipath protection scheme is evaluated by means of experiment on our OpenFlow-based testbed. The feasibility of our proposed scheme is also demonstrated in software defined elastic optical networks.

  1. Acne neonatorum in the eastern Saudi Arabia

    Directory of Open Access Journals (Sweden)

    Alakloby Omar

    2008-01-01

    Full Text Available Background: Acne neonatorum (AN is characterized by a facial eruption of inflammatory and noninflammatory acne lesions in a neonate. Hyperactivity of sebaceous glands, stimulated by neonatal androgens, is implicated in its pathogenesis. Aim: To elucidate the clinical profile of AN in eastern Saudi Arabia. Methods: All patients diagnosed with AN in King Fahd Hospital of the University in Khobar, Saudi Arabia, during the year 2005 were evaluated clinically. Results: AN was diagnosed in 26 patients (male/female ratio 1:1. The lesions included mainly facial comedones (30.8%; papules and pustules (15.3% each; and combination of papules, pustules, and cysts (53.4%. Conclusion: All patients recovered spontaneously. In 50% of the cases, one of the parents reported having had acne vulgaris during adolescence. Hereditary factors seem to play a significant role in our series.

  2. Fraxelated radiofrequency device for acne scars

    Science.gov (United States)

    Rao, Babar K.; Khokher, Sairah

    2012-09-01

    Acne scars can be improved with various treatments such as topical creams, chemical peels, dermal fillers, microdermabrasion, laser, and radiofrequency devices. Some of these treatments especially lasers and deep chemical peels can have significant side effects such as post inflammatory hyperpigmentation in darker skin types. Fraxelated RF Laser devices have been reported to have lower incidence of side effects in all skin phototypes. Nine patients between ages 18 and 35 of various skin phototypes were selected from a private practice and treated with a RF fraxelated device (E-matrix) for acne scars. Outcomes were measured by physician observation, subjective feedback received by patients, and comparison of before and after photographs. In this small group of patients with various skin phototypes, fraxelated radiofrequency device improved acne scars with minimal side effects and downtime.

  3. Information services in social networked transportation : governance and ITS.

    Science.gov (United States)

    2014-06-01

    The purpose of this research seeks to understand the functions and the benefits of social : networked transportation (SNT), the processes that make SNT possible, and the institutional : innovations needed to facilitate those processes. First, this re...

  4. Models and Tabu Search Metaheuristics for Service Network Design with Asset-Balance Requirements

    DEFF Research Database (Denmark)

    Pedersen, Michael Berliner; Crainic, T.G.; Madsen, Oli B.G.

    2009-01-01

    design model, a generalization of the capacitated multicommodity network design model generally used in service network design applications. Both arc-and cycle-based formulations for the new model are presented. The paper also proposes a tabu search metaheuristic framework for the arc-based formulation...

  5. Enriching the Tactical Network Design of Express Service Carriers with Fleet Scheduling Characteristics

    NARCIS (Netherlands)

    Meuffels, W.J.M.; Fleuren, H.A.; Cruijssen, F.C.A.M.; van Dam, E.R.

    2009-01-01

    Express service carriers provide time-guaranteed deliveries of parcels via a network consisting of nodes and hubs. In this, nodes take care of the collection and delivery of parcels, and hubs have the function to consolidate parcels in between the nodes. The tactical network design problem assigns

  6. Enriching the tactical network design of express service carriers with fleet scheduling characteristics

    NARCIS (Netherlands)

    Meuffels, W.J.M.; Fleuren, H.A.; Cruijssen, F.C.A.M.; Dam, E.R.

    2010-01-01

    Express service carriers provide time-guaranteed deliveries of parcels via a network consisting of nodes and hubs. In this, nodes take care of the collection and delivery of parcels, and hubs have the function to consolidate parcels in between the nodes. The tactical network design problem assigns

  7. Childhood ADHD Symptoms: Association with Parental Social Networks and Mental Health Service Use during Adolescence.

    Science.gov (United States)

    Bussing, Regina; Meyer, Johanna; Zima, Bonnie T; Mason, Dana M; Gary, Faye A; Garvan, Cynthia Wilson

    2015-09-22

    This study examines the associations of childhood attention-deficit/hyperactivity disorder (ADHD) risk status with subsequent parental social network characteristics and caregiver strain in adolescence; and examines predictors of adolescent mental health service use. Baseline ADHD screening identified children at high risk (n = 207) and low risk (n = 167) for ADHD. At eight-year follow-up, parents reported their social network characteristics, caregiver strain, adolescents' psychopathology and mental health service utilization, whereas adolescents self-reported their emotional status and ADHD stigma perceptions. Analyses were conducted using ANOVAs and nested logistic regression modeling. Parents of youth with childhood ADHD reported support networks consisting of fewer spouses but more healthcare professionals, and lower levels of support than control parents. Caregiver strain increased with adolescent age and psychopathology. Increased parental network support, youth ADHD symptoms, and caregiver strain, but lower youth stigma perceptions were independently associated with increased service use. Raising children with ADHD appears to significantly impact parental social network experiences. Reduced spousal support and overall lower network support levels may contribute to high caregiver strain commonly reported among parents of ADHD youth. Parental social network experiences influence adolescent ADHD service use. With advances in social networking technology, further research is needed to elucidate ways to enhance caregiver support during ADHD care.

  8. Childhood ADHD Symptoms: Association with Parental Social Networks and Mental Health Service Use during Adolescence

    Directory of Open Access Journals (Sweden)

    Regina Bussing

    2015-09-01

    Full Text Available Objective: This study examines the associations of childhood attention-deficit/hyperactivity disorder (ADHD risk status with subsequent parental social network characteristics and caregiver strain in adolescence; and examines predictors of adolescent mental health service use. Methods: Baseline ADHD screening identified children at high risk (n = 207 and low risk (n = 167 for ADHD. At eight-year follow-up, parents reported their social network characteristics, caregiver strain, adolescents’ psychopathology and mental health service utilization, whereas adolescents self-reported their emotional status and ADHD stigma perceptions. Analyses were conducted using ANOVAs and nested logistic regression modeling. Results: Parents of youth with childhood ADHD reported support networks consisting of fewer spouses but more healthcare professionals, and lower levels of support than control parents. Caregiver strain increased with adolescent age and psychopathology. Increased parental network support, youth ADHD symptoms, and caregiver strain, but lower youth stigma perceptions were independently associated with increased service use. Conclusions: Raising children with ADHD appears to significantly impact parental social network experiences. Reduced spousal support and overall lower network support levels may contribute to high caregiver strain commonly reported among parents of ADHD youth. Parental social network experiences influence adolescent ADHD service use. With advances in social networking technology, further research is needed to elucidate ways to enhance caregiver support during ADHD care.

  9. Optimal Sizing and Allocation of Residential Photovoltaic Panels in a Distribution Network for Ancillary Services Application

    DEFF Research Database (Denmark)

    Kordheili, Reza Ahmadi; Pourmousavi, Ali; Pillai, Jayakrishnan Radhakrishna

    2014-01-01

    Tremendous penetration of renewable energy in electric networks, despite its valuable opportunities, such as balancing reserve and ancillary service, has raised concerns for network operators. Such concern stems from grid operating conditions. Such huge penetration can lead to violation in the gr...

  10. Review Of Prevention Techniques For Denial Of Service DOS Attacks In Wireless Sensor Network

    Directory of Open Access Journals (Sweden)

    Poonam Rolla

    2015-08-01

    Full Text Available Wireless Sensor Networks comprised of several tiny sensor nodes which are densely deployed over the region to monitor the environmental conditions. These sensor nodes have certain design issues out of which security is the main predominant factor as it effects the whole lifetime of network. DDoS Distributed denial of service attack floods unnecessary packets in the sensor network. A review on DDoS attacks and their prevention techniques have been done in this paper.

  11. Quality of Service Issues for Reinforcement Learning Based Routing Algorithm for Ad-Hoc Networks

    OpenAIRE

    Kulkarni, Shrirang Ambaji; Rao, G. Raghavendra

    2012-01-01

    Mobile ad-hoc networks are dynamic networks which are decentralized and autonomous in nature. Many routing algorithms have been proposed for these dynamic networks. It is an important problem to model Quality of Service requirements on these types of algorithms which traditionally have certain limitations. To model this scenario we have considered a reinforcement learning algorithm SAMPLE. SAMPLE promises to deal effectively with congestion and under high traffic load. As it is natural for ad...

  12. An empirical study of the social individual differences on mobile social network service use

    OpenAIRE

    Alkhunaizan, A; Love, S.

    2013-01-01

    Copyright @ 2013 EMCIS. When developing and aiming to achieve success in the arena of mobile social network services, user behaviour is one of the key aspects for consideration. Nowadays, it is recognised that mobile social networks are fast, responsive technologies centred on facilitating mobile commerce. Our aim in this study to perform an empirical study to investigate the way in which social individual factors (gender, age and education) affect user acceptance in mobile social network ...

  13. Review Of Prevention Techniques For Denial Of Service DOS Attacks In Wireless Sensor Network

    OpenAIRE

    Poonam Rolla; Manpreet Kaur

    2015-01-01

    Wireless Sensor Networks comprised of several tiny sensor nodes which are densely deployed over the region to monitor the environmental conditions. These sensor nodes have certain design issues out of which security is the main predominant factor as it effects the whole lifetime of network. DDoS Distributed denial of service attack floods unnecessary packets in the sensor network. A review on DDoS attacks and their prevention techniques have been done in this paper.

  14. Towards Service-oriented 5G: Virtualizing the Networks for Everything-as-a-Service

    OpenAIRE

    Chang, Zheng; Zhou, Zhenyu; Zhou, Sheng; Ristaniemi, Tapani; Niu, Zhisheng

    2016-01-01

    It is widely acknowledged that the forthcoming 5G architecture will be highly heterogeneous and deployed with a high degree of density. These changes over the current 4G bring many challenges on how to achieve an efficient operation from the network management perspective. In this article, we introduce a revolutionary vision of the future 5G wireless networks, in which the network is no longer limited by hardware or even software. Specifically, by the idea of virtualizing the wireless network...

  15. A Study of Quality of Service Communication for High-Speed Packet-Switching Computer Sub-Networks

    Science.gov (United States)

    Cui, Zhenqian

    1999-01-01

    With the development of high-speed networking technology, computer networks, including local-area networks (LANs), wide-area networks (WANs) and the Internet, are extending their traditional roles of carrying computer data. They are being used for Internet telephony, multimedia applications such as conferencing and video on demand, distributed simulations, and other real-time applications. LANs are even used for distributed real-time process control and computing as a cost-effective approach. Differing from traditional data transfer, these new classes of high-speed network applications (video, audio, real-time process control, and others) are delay sensitive. The usefulness of data depends not only on the correctness of received data, but also the time that data are received. In other words, these new classes of applications require networks to provide guaranteed services or quality of service (QoS). Quality of service can be defined by a set of parameters and reflects a user's expectation about the underlying network's behavior. Traditionally, distinct services are provided by different kinds of networks. Voice services are provided by telephone networks, video services are provided by cable networks, and data transfer services are provided by computer networks. A single network providing different services is called an integrated-services network.

  16. Expanding Global Production Networks: The emergence, evolution and the developmental impact of the offshore service sector in the Philippines

    NARCIS (Netherlands)

    Kleibert, J.M.

    2015-01-01

    Contemporary globalisation is characterised by an expansion of global production networks in services. Developments in information and communications technology have enabled the relocation of services across national borders, or, the offshoring of services. This has had profound implications for

  17. Pseudo-acne fulminans associated with oral isotretinoin*

    Science.gov (United States)

    Grando, Luciana Rosa; Leite, Oriete Gerin; Cestari, Tania Ferreira

    2014-01-01

    Acne fulminans is a rare and serious condition characterized by the sudden onset of nodular and ulcerative acne lesions associated with systemic symptoms. It has been recognized a subset of patients with a sudden worsening of acne, often during treatment with oral isotretinoin, but without the strong presence of systemic involvement. Recognized by some authors as "pseudo-acne fulminans" or " acne fulminans sine fulminans," we report a case with these features in order to draw attention to the recognition and early management of this manifestation. PMID:25054758

  18. Acne Scarring—Pathogenesis, Evaluation, and Treatment Options

    Science.gov (United States)

    Connolly, Deirdre; Vu, Ha Linh; Mariwalla, Kavita

    2017-01-01

    Acne vulgaris is a ubiquitous problem affecting 80 percent of people ages 11 to 30 years, with many patients experiencing some degree of scarring. This review focuses on atrophic scars, the most common type of acne scar. We briefly address the cellular sequelae that lead to scar formation and the initial evaluation of patients with acne scars. We then discuss an algorithmic approach to the treatment of acne scarring based on the classification of scars into erythematous and atrophic types. Lastly, we discuss the future treatment of acne scars and ongoing clinical trials. PMID:29344322

  19. Isotretinoin influences pituitary hormone levels in acne patients.

    Science.gov (United States)

    Karadag, Ayse Serap; Ertugrul, Derun Taner; Tutal, Emre; Akin, Kadir Okhan

    2011-01-01

    Besides suppressing sebum production, the exact mechanism of action of isotretinoin in acne vulgaris is not known. Several hormones have been linked to the pathogenesis of acne. In this study, we investigated the effects of isotretinoin on the pituitary-adrenal axis, whose activity may be increased in acne. Various hormone systems were evaluated before and after 3 months of isotretinoin treatment in 47 acne patients. Free triiodothyronine (T3), thyroid-stimulating hormone and thyroid-stimulating hormone receptor antibody levels decreased significantly during isotretinoin treatment (p testosterone (p isotretinoin causes mild suppression of pituitary hormone levels, which may be beneficial for tackling the pathogenesis of acne.

  20. Phototherapy in the treatment of acne vulgaris.

    Science.gov (United States)

    Sami, Nevien A; Attia, Abeer T; Badawi, Ashraf M

    2008-07-01

    Achieving an effective management of acne vulgaris with minimal complications remains a difficult challenge for physicians. Moreover, the rise in antibiotic-resistant strains reduce the future usefulness of current mainstay therapies, and accordingly, the need for alternative therapies is mandatory. Phototherapy has been shown to be an effective treatment for acne, and there has been a renewed interest in photodynamic therapy as a treatment modality for this condition. To evaluate the effectiveness of pulsed dye laser (PDL), intense pulsed light (IPL) and light-emitting diode (LED) phototherapy for the treatment of moderate to severe acne vulgaris. Forty-five patients with moderate to severe acne were randomly divided into 3 equal groups. Group 1 was treated with a PDL, group 2 was treated with IPL, and group 3 was treated with a blue-red combination LED. Treatment was continued until a > or = 90% clearance of patient lesions was achieved. Clinical assessments were conducted before starting treatment, at 1 month as a midpoint evaluation, and after the final treatment session. Patients treated with the PDL reached a > or = 90% clearance of their inflammatory lesions after a mean of 4.1 +/- 1.39 sessions, while patients treated with IPL required a mean of 6 +/- 2.05 sessions. Patients treated with the LED required a mean of 10 +/- 3.34 sessions. At the mid-point evaluation, the percent reduction in acne lesions treated with the PDL was 90% or more, in cases of IPL and the LED, the percent reductions were 41.7% and 35.3%, respectively. Laser and light phototherapy sessions were well tolerated with minimal adverse events experienced as being mild and usually self-limiting. The encouraging results of the present study contributes evidence of phototherapy as useful therapeutic option for treatment of moderate to severe acne, and validates further studies to evaluate treatments with a larger number of patients and for a longer period of follow-up.

  1. Design of RFID Cloud Services in a Low Bandwidth Network Environment

    Directory of Open Access Journals (Sweden)

    John P.T. Mo

    2011-02-01

    Full Text Available The use of Information and Communication Technologies has significantly improved the efficiency of modern supply chains. Existing IT architecture is too rigid to allow new technologies such as RFID technologies to be implemented. With the aid of virtualisation and integrated with cloud services, infrastructure hardware and network devices can be consolidated into a physical device, reducing the cost of ownership. However, for such cloud services model to work correctly, a high speed network is required between each site and the cloud service provider. This poses huge challenges for real‐time system such as RFID‐enabled supply chains. Since modern supply chains operate on a global platform, it is almost impossible to assure availability of high speed networks across the global supply chain. This paper proposes two solutions to supplement the virtualisation and cloud services model. A sub‐cloud services solution, where each service is distributed across multiple hosts across different countries and regions is proposed to enhance accessibility to higher bandwidth networks. The second solution is the Queued Burst Device Compression system incorporates a compression service that compresses RFID data sets into much smaller packages. This solution is proved to work by a multiple‐in‐single‐out queuing model and is suitable for low bandwidth networks such as GPRS and 3G wireless environmenst.

  2. Quality of Service in Bluetooth networking - part I

    NARCIS (Netherlands)

    van der Zee, Martin; Heijenk, Geert

    The Quality of Service functions and procedures included in the Bluetooth 1.0 specification have been reviewed. Next issues associated with providing Quality of Service over a wireless link in general and Bluetooth in particular have been investigated. Allthough the Bluetooth 1.0 specification

  3. Distributed Service Discovery within Mobile Ad Hoc Networks

    Science.gov (United States)

    2011-09-20

    it is a super-peer; in Napster [7], it is the central Napster server; in JXTA [8], it is a rendezvous; in Web services, UDDI [9] may be used as the...6. Bonjour, see http://developer.apple.com/bonjour/. Distributed Service Discovery within MANETs 13 7. Napster , see http: // www.napster.com/. 8

  4. Balancing functionality, risk, and cost in smart service networks

    NARCIS (Netherlands)

    Batubara, Fakhruddin Rizal

    2015-01-01

    Recent developments in the area of software service systems brought a new level of scale, complexity and pervasiveness to cope with. This has, in turn, changed the business model of companies engaged in the software industry and the way they present their services. Healthcare systems, as an example,

  5. Retinoid plus antimicrobial combination treatments for acne

    Directory of Open Access Journals (Sweden)

    Feneran A

    2011-07-01

    Full Text Available Ashley N Feneran1, William S Kaufman2, Tushar S Dabade1, Steven R Feldman1,3,41Department of Dermatology, Center for Dermatology Research, Wake Forest University School of Medicine, Winston-Salem, NC, USA; 2Medical College of Virginia, Richmond, VA, USA; 3Department of Pathology, Center for Dermatology Research, Wake Forest University School of Medicine, Winston-Salem, NC, USA; 4Department of Public Health Sciences, Center for Dermatology Research, Wake Forest University School of Medicine, Winston-Salem, NC, USABackground: Acne vulgaris is a chronic disease with several pathogenic factors. Multiple medications are typically used that can lead to nonadherence and treatment failure. Combination medications target multiple pathways of acne formation and may offer therapeutic benefit.Purpose: To explore the efficacy and tolerability of combination retinoid plus antimicrobial treatments in acne vulgaris.Methods: A PubMed and Google search was conducted for combination therapies of clindamycin and tretinoin, with secondary analysis of related citations and references. Similar searches were completed for the combination medications of benzoyl peroxide plus clindamycin or erythromycin, and for the combination therapy of adapalene and benzoyl peroxide.Results: Combination clindamycin phosphate and tretinoin gel was found to be more efficacious than monotherapy of either drug or its vehicle for acne, including inflammatory acne, and has a greater onset of action than either drug alone. Clindamycin phosphate and tretinoin gel was well-tolerated, and adherence to its use exceeded that of using both medications in separate formulations. Benzoyl peroxide-containing combination medications with clindamycin or erythromycin were both more effective in the treatment of acne than either drug alone. Both medications were well-tolerated, with dry skin being the most common adverse effect.Conclusions: Combination medications have superior efficacy and adherence, and

  6. Lithium induced hidradenitis suppurativa and acne conglobata

    Directory of Open Access Journals (Sweden)

    Aithal Vijay

    2004-09-01

    Full Text Available Lithium is known to cause a variety of dermatological problems, common ones being acneiform eruptions, folliculitis and psoriasis including its pustular form. Hidradenitis suppurativa and acne conglobata are lesser known side effects, with only three reports so far. We report a patient, who had bipolar affective disorder, was on lithium for a long duration and developed hidradenitis suppurativa and acne conglobata during therapy, which subsequently decreased once lithium was stopped. We describe this case for its rarity and analyze its pathogenesis.

  7. Consumption of dairy in teenagers with and without acne.

    Science.gov (United States)

    LaRosa, Caroline L; Quach, Kim A; Koons, Kirsten; Kunselman, Allen R; Zhu, Junjia; Thiboutot, Diane M; Zaenglein, Andrea L

    2016-08-01

    Recent literature has implicated dairy as having a potential acne-inducing effect. The aim of this study was to investigate the link between dairy consumption and acne in teenagers. We tested the hypothesis that teenagers with facial acne consume more dairy than those without acne. A case-control study was conducted among 225 participants, ages 14 to 19 years, with either moderate acne or no acne. Moderate acne was determined by a dermatologist using the Global Acne Assessment Scale. Participants who met inclusion criteria then completed up to three 24-hour diet recall interviews using the Nutrition Data System for Research software and food and nutrient intake were compared between groups. The amount of low-fat/skim milk consumed by participants with acne with significantly higher (P = .01) than those with no acne. No significant difference was found among total dairy intake, saturated fat or trans-fat, or glycemic load. No significant difference was found for total energy intake or body mass index. Limitations include self-report of diet and portion size, and association does not determine causation. Consumption of low-fat/skim milk, but not full-fat milk, was positively associated with acne. Copyright © 2016 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.

  8. Fluorescence guided evaluation of photodynamic therapy as acne treatment

    Science.gov (United States)

    Ericson, Marica B.; Horfelt, Camilla; Cheng, Elaine; Larsson, Frida; Larko, Olle; Wennberg, Ann-Marie

    2005-08-01

    Photodynamic therapy (PDT) is an attractive alternative treatment for patients with acne because of its efficiency and few side effects. Propionibacterium acnes (P.acnes) are bacteria present in the skin, which produce endogenous porphyrins that act as photosensitisers. In addition, application of aminolaevulinic acid or its methyl ester (mALA) results in increased accumulation of porphyrins in the pilosebaceous units. This makes it possible to treat acne with PDT. This initial study investigates the possibility of fluorescence imaging as assessment tool in adjunct to PDT of patients with acne. Twenty-four patients with acne on the cheeks have been treated with PDT with and without mALA. Fluorescence images have been obtained before and after treatment. The clinical acne score was assessed as base line before PDT, and at every follow up visit. Additionally the amount of P.acnes was determined. The clinical evaluation showed a general improvement of acne, even though no difference between treatment with and without mALA was observed. By performing texture analysis and multivariate data analsysis on the fluorescence images, the extracted texture features were found to correlate with the corresponding clinical assessment (67%) and amount of P.acnes (72%). The analysis showed that features describing the highly fluorescent pores could be related to the clinical assessment. This result suggests that fluorescence imaging can be used as an objective assessment of acne, but further improvement of the technique is possible, for example by including colour images.

  9. Sociodemographic Characteristics of Acne among University Students in Damascus, Syria

    Directory of Open Access Journals (Sweden)

    Waqar Al-Kubaisy

    2014-01-01

    Full Text Available To estimate the prevalence and identify risk factors that may be associated with acne among university students in Syria, a cross-sectional study was conducted in the Syrian International University for Science and Technology in December 2009. A sample of 500 students was chosen. Each participant was subjected to an interview and clinical examination of acne in addition to height and weight measurements. Acne prevalence was 34.7% (172/496. Male students had higher rate of acne compared to females (42.9% versus 23.6%, P<0.0001 and their acne started significantly at a younger age (18.13 versus 19.04 years old, P<0.0001. Face was the commonest site for acne in both males and females. Washing face frequently per day in both sexes has a significant relation with a decreased prevalence of acne. Moreover, psychological stress particularly when the students were away from family was associated with a significant higher rate of acne. We found that the prevalence of acne steadily increased with increasing body mass index. Acne is a health and psychological problem among university students particularly when affecting the face. Several factors such as gender, body mass index, and stress were found to be associated with acne formation.

  10. Significance of diet in treated and untreated acne vulgaris.

    Science.gov (United States)

    Kucharska, Alicja; Szmurło, Agnieszka; Sińska, Beata

    2016-04-01

    The relationship between diet and acne is highly controversial. Several studies during the last decade have led dermatologists to reflect on a potential link between diet and acne. This article presents the latest findings on a potential impact that diet can have on pathogenesis of acne vulgaris. The association between diet and acne can no longer be dismissed. Compelling evidence shows that high glycemic load diets may exacerbate acne. Dairy ingestion appears to be weakly associated with acne and the roles of omega-3 fatty acids, dietary fiber, antioxidants, vitamin A, zinc and iodine remain to be elucidated. The question of what the impact of diet is on the course of acne vulgaris still remains unclear.

  11. Significance of diet in treated and untreated acne vulgaris

    Directory of Open Access Journals (Sweden)

    Alicja Kucharska

    2016-05-01

    Full Text Available The relationship between diet and acne is highly controversial. Several studies during the last decade have led dermatologists to reflect on a potential link between diet and acne. This article presents the latest findings on a potential impact that diet can have on pathogenesis of acne vulgaris. The association between diet and acne can no longer be dismissed. Compelling evidence shows that high glycemic load diets may exacerbate acne. Dairy ingestion appears to be weakly associated with acne and the roles of omega-3 fatty acids, dietary fiber, antioxidants, vitamin A, zinc and iodine remain to be elucidated. The question of what the impact of diet is on the course of acne vulgaris still remains unclear.

  12. Acne is not Associated with yet Uncultured Bacteria

    DEFF Research Database (Denmark)

    Bek-Thomsen, Malene; Lomholt, Hans Bredsted; Kilian, Mogens

    2008-01-01

    Current clinical and microbiological information on acne fail to demonstrate a clear association between particular species, including Propionibacterium acnes, and disease, and the disease continues to be a considerable problem. To test if acne is associated with hitherto uncultured bacteria...... residing in diseased skin follicles, sequencing and phylogenetic analysis of approximately 5,700 amplified and cloned 16S rRNA genes were used to determine the microbial diversity in follicles from acne patients and healthy individuals and from superficial skin of acne patients. Follicles from healthy skin...... were exclusively colonized by P. acnes, whereas the follicular microbiota of acne patients, in addition, included S. epidermidis and minor proportions of other species. In comparison, samples from superficial skin showed a complex microbiota with 12 to 16 bacterial species represented. The study...

  13. Do generalists and specialists agree on descriptive acne morphology?

    DEFF Research Database (Denmark)

    Yazdanyar, S; Bryld, L E; Heidenheim, M

    2013-01-01

    BACKGROUND: Acne is a common skin disease, which is treated by many different specialities. Clinical guidelines for treatment are based on the recognition of acne morphology. The assessment of acne morphology is therefore an important element of the proper diagnosis and treatment of acne. OBJECTIVE......: To evaluate the level of congruence in the assessment of acne morphology in General Practitioners (GPs) and Dermatologists compared to the assessment of an expert. METHODS: The study was conducted during 2008-2009. Randomly selected GP and Dermatologists Practitioners, (DPs) from Denmark were invited...... in the distribution of answers. CONCLUSION: GPs described acne morphology recognized clinical hallmarks of severity in acne less well than dermatologists and were far less consistent....

  14. Data-Intensive Cloud Service Provision for Research Institutes: the Network Connectivity Problem

    CERN Document Server

    Cass, Tony; CERN. Geneva. IT Department

    2016-01-01

    Much effort (and money) has been invested in recent years to ensure that academic and research sites are well interconnected with high-capacity networks that, in most cases, span national and continental boundaries. However, these dedicated research and education networks, whether national (NRENs) or trans-continental (RENs), frequently have Acceptable Use Policies (AUPs) that restrict their use by commercial entities, notably Cloud Service Providers (CSPs). After a brief summary of the issues involved, we describe three approaches to removing the network connectivity barrier that threatens to limit the ability of academic and research institutions to profit effectively from services offered by CSPs.

  15. Practical management of acne for clinicians: An international consensus from the Global Alliance to Improve Outcomes in Acne.

    Science.gov (United States)

    Thiboutot, Diane M; Dréno, Brigitte; Abanmi, Abdullah; Alexis, Andrew F; Araviiskaia, Elena; Barona Cabal, Maria Isabel; Bettoli, Vincenzo; Casintahan, Flordeliz; Chow, Steven; da Costa, Adilson; El Ouazzani, Tam; Goh, Chee-Leok; Gollnick, Harald P M; Gomez, Minerva; Hayashi, Nobukazu; Herane, Maria Isabel; Honeyman, Juan; Kang, Sewon; Kemeny, Lajos; Kubba, Raj; Lambert, Julien; Layton, Alison M; Leyden, James J; López-Estebaranz, Jose Luis; Noppakun, Nopadon; Ochsendorf, Falk; Oprica, Cristina; Orozco, Beatriz; Perez, Montserrat; Piquero-Martin, Jaime; See, Jo-Ann; Suh, Dae Hun; Tan, Jerry; Lozada, Vicente Torres; Troielli, Patricia; Xiang, Leihong Flora

    2018-02-01

    Scientific advances are continually improving the knowledge of acne and contributing to the refinement of treatment options; it is important for clinicians to regularly update their practice patterns to reflect current standards. The Global Alliance to Improve Outcomes in Acne is an international group of dermatologists with an interest in acne research and education that has been meeting regularly since 2001. As a group, we have continuously evaluated the literature on acne. This supplement focuses on providing relevant clinical guidance to health care practitioners managing patients with acne, with an emphasis on areas where the evidence base may be sparse or need interpretation for daily practice. Copyright © 2017. Published by Elsevier Inc.

  16. Coherent detection passive optical access network enabling converged delivery of broadcast and dedicated broadband services

    DEFF Research Database (Denmark)

    Osadchiy, Alexey Vladimirovich; Prince, Kamau; Guerrero Gonzalez, Neil

    2011-01-01

    We propose a passive optical network architecture based on coherent detection for converged delivery of broadcast services from a dedicated remote broadcast server and user-specific services from a local central office. We experimentally demonstrate this architecture with mixed traffic types, wav...

  17. [Semantic Network Analysis of Online News and Social Media Text Related to Comprehensive Nursing Care Service].

    Science.gov (United States)

    Kim, Minji; Choi, Mona; Youm, Yoosik

    2017-12-01

    As comprehensive nursing care service has gradually expanded, it has become necessary to explore the various opinions about it. The purpose of this study is to explore the large amount of text data regarding comprehensive nursing care service extracted from online news and social media by applying a semantic network analysis. The web pages of the Korean Nurses Association (KNA) News, major daily newspapers, and Twitter were crawled by searching the keyword 'comprehensive nursing care service' using Python. A morphological analysis was performed using KoNLPy. Nodes on a 'comprehensive nursing care service' cluster were selected, and frequency, edge weight, and degree centrality were calculated and visualized with Gephi for the semantic network. A total of 536 news pages and 464 tweets were analyzed. In the KNA News and major daily newspapers, 'nursing workforce' and 'nursing service' were highly rated in frequency, edge weight, and degree centrality. On Twitter, the most frequent nodes were 'National Health Insurance Service' and 'comprehensive nursing care service hospital.' The nodes with the highest edge weight were 'national health insurance,' 'wards without caregiver presence,' and 'caregiving costs.' 'National Health Insurance Service' was highest in degree centrality. This study provides an example of how to use atypical big data for a nursing issue through semantic network analysis to explore diverse perspectives surrounding the nursing community through various media sources. Applying semantic network analysis to online big data to gather information regarding various nursing issues would help to explore opinions for formulating and implementing nursing policies.

  18. A web-based information system for a regional public mental healthcare service network in Brazil.

    Science.gov (United States)

    Yoshiura, Vinicius Tohoru; de Azevedo-Marques, João Mazzoncini; Rzewuska, Magdalena; Vinci, André Luiz Teixeira; Sasso, Ariane Morassi; Miyoshi, Newton Shydeo Brandão; Furegato, Antonia Regina Ferreira; Rijo, Rui Pedro Charters Lopes; Del-Ben, Cristina Marta; Alves, Domingos

    2017-01-01

    Regional networking between services that provide mental health care in Brazil's decentralized public health system is challenging, partly due to the simultaneous existence of services managed by municipal and state authorities and a lack of efficient and transparent mechanisms for continuous and updated communication between them. Since 2011, the Ribeirao Preto Medical School and the XIII Regional Health Department of the Sao Paulo state, Brazil, have been developing and implementing a web-based information system to facilitate an integrated care throughout a public regional mental health care network. After a profound on-site analysis, the structure of the network was identified and a web-based information system for psychiatric admissions and discharges was developed and implemented using a socio-technical approach. An information technology team liaised with mental health professionals, health-service managers, municipal and state health secretariats and judicial authorities. Primary care, specialized community services, general emergency and psychiatric wards services, that comprise the regional mental healthcare network, were identified and the system flow was delineated. The web-based system overcame the fragmentation of the healthcare system and addressed service specific needs, enabling: detailed patient information sharing; active coordination of the processes of psychiatric admissions and discharges; real-time monitoring; the patients' status reports; the evaluation of the performance of each service and the whole network. During a 2-year period of operation, it registered 137 services, 480 health care professionals and 4271 patients, with a mean number of 2835 accesses per month. To date the system is successfully operating and further expanding. We have successfully developed and implemented an acceptable, useful and transparent web-based information system for a regional mental healthcare service network in a medium-income country with a decentralized

  19. Highway Passenger Transport Based Express Parcel Service Network Design: Model and Algorithm

    Directory of Open Access Journals (Sweden)

    Yuan Jiang

    2017-01-01

    Full Text Available Highway passenger transport based express parcel service (HPTB-EPS is an emerging business that uses unutilised room of coach trunk to ship parcels between major cities. While it is reaping more and more express market, the managers are facing difficult decisions to design the service network. This paper investigates the HPTB-EPS network design problem and analyses the time-space characteristics of such network. A mixed-integer programming model is formulated integrating the service decision, frequency, and network flow distribution. To solve the model, a decomposition-based heuristic algorithm is designed by decomposing the problem as three steps: construction of service network, service path selection, and distribution of network flow. Numerical experiment using real data from our partner company demonstrates the effectiveness of our model and algorithm. We found that our solution could reduce the total cost by up to 16.3% compared to the carrier’s solution. The sensitivity analysis demonstrates the robustness and flexibility of the solutions of the model.

  20. Multi Service Proxy: Mobile Web Traffic Entitlement Point in 4G Core Network

    Directory of Open Access Journals (Sweden)

    Dalibor Uhlir

    2015-05-01

    Full Text Available Core part of state-of-the-art mobile networks is composed of several standard elements like GGSN (Gateway General Packet Radio Service Support Node, SGSN (Serving GPRS Support Node, F5 or MSP (Multi Service Proxy. Each node handles network traffic from a slightly different perspective, and with various goals. In this article we will focus only on the MSP, its key features and especially on related security issues. MSP handles all HTTP traffic in the mobile network and therefore it is a suitable point for the implementation of different optimization functions, e.g. to reduce the volume of data generated by YouTube or similar HTTP-based service. This article will introduce basic features and functions of MSP as well as ways of remote access and security mechanisms of this key element in state-of-the-art mobile networks.

  1. The effect of Propionibacterium acnes on maturation of dendritic cells derived from acne patients' peripherial blood mononuclear cells.

    Directory of Open Access Journals (Sweden)

    Maria Juszkiewicz-Borowiec

    2009-01-01

    Full Text Available Propionibacterium acnes (P. acnes has been implicated in the pathogenesis of acne vulgaris which is the most common cutaneous disorder. It has a proinflammatory activity and takes part in immune reactions modulating the Th1/Th2 cellular response. The exposure of dendritic cells (DCs to whole bacteria, their components, cytokines or other inflammatory stimuli and infectious agents induces differentiation from immature DCs into antigen-presenting mature DCs. The aim of the study was to evaluate the capability of P. acnes to induce the maturation of DCs. We stimulated monocyte derived dendritic cells (Mo-DCs from acne patients with various concetrations of heat-killed P. acnes (10(6-10(8 bacteria/ml cultured from acne lesions. The results showed an increase in CD80+/CD86+/DR+ and CD83+/CD1a+/DR+ cells percentage depending on the concetration of P. acnes. The expression of CD83 and CD80 (shown as the mean fluorescence intensity - MFI increased with higher concetrations of P. acnes. There were also significant correlations between MFI of CD83, CD80, CD86 and concetration of P. acnes. The study showed that P. acnes in the concetration of 10(8 bacteria/ml is most effective in the induction of Mo-DCs maturation. Futher studies concerning the influence on the function of T cells are needed.

  2. Propionibacterium acnes Induces an IL-17 Response in Acne Vulgaris that Is Regulated by Vitamin A and Vitamin D.

    Science.gov (United States)

    Agak, George W; Qin, Min; Nobe, Jennifer; Kim, Myung-Hwa; Krutzik, Stephan R; Tristan, Grogan R; Elashoff, David; Garbán, Hermes J; Kim, Jenny

    2014-02-01

    Acne vulgaris is the most common skin disorder affecting millions of people worldwide and inflammation resulting from the immune response targeting Propionibacterium acnes has a significant role in its pathogenesis. In this study, we have demonstrated that P. acnes is a potent inducer of T helper 17 (Th17) and Th1, but not Th2 responses in human peripheral blood mononuclear cells (PBMCs). P. acnes stimulated expression of key Th17-related genes, including IL-17A, RORα, RORc, IL-17RA, and IL-17RC, and triggered IL-17 secretion from CD4(+), but not from CD8(+) T cells. Supernatants from P. acnes-stimulated PBMCs were sufficient to promote the differentiation of naive CD4(+)CD45RA T cells into Th17 cells. Furthermore, we found that the combination of IL-1β, IL-6, and transforming growth factor-β-neutralizing antibodies completely inhibited P. acnes-induced IL-17 production. Importantly, we showed that IL-17-expressing cells were present in skin biopsies from acne patients but not from normal donors. Finally, vitamin A (all-trans retinoic acid) and vitamin D (1,25-dihydroxyvitamin D3) inhibited P. acnes-induced Th17 differentiation. Together, our data demonstrate that IL-17 is induced by P. acnes and expressed in acne lesions and that both vitamin A and D could be effective tools to modulate Th17-mediated diseases such as acne.

  3. Multiple access protocol for supporting multimedia services in wireless ATM networks

    DEFF Research Database (Denmark)

    Liu, Hong; Dittmann, Lars; Gliese, Ulrik Bo

    1999-01-01

    The furture broadband wireless asynchronous transfer mode (ATM) networks must provide seamless extension of multimedia services from the wireline ATM networks. This requires an effecient wireless access protocol to fulfill varying Quality-og-Service (QoS) requirements for multimedia applications....... In this paper, we propose a multiple access protocol using centralized and distributed channel access control techniques to provide QoS guarantees for multimedia services by taking advantage of the characteristics of different kinds of ATM traffics. Multimedia traffic, including constant bit rate (CBR...

  4. A service flow model for the liner shipping network design problem

    DEFF Research Database (Denmark)

    Plum, Christian Edinger Munk; Pisinger, David; Sigurd, Mikkel M.

    2014-01-01

    Global liner shipping is a competitive industry, requiring liner carriers to carefully deploy their vessels efficiently to construct a cost competitive network. This paper presents a novel compact formulation of the liner shipping network design problem (LSNDP) based on service flows...... of the network and a penalty for not flowed cargo. The model can be used to design liner shipping networks to utilize a container carrier’s assets efficiently and to investigate possible scenarios of changed market conditions. The model is solved as a Mixed Integer Program. Results are presented for the two...

  5. Managerial Networks and Exploration in a Professional Service Firm

    DEFF Research Database (Denmark)

    Rogan, Michelle; Mors, Louise

    2017-01-01

    A firm’s growth and survival depends on the ability of its managers to explore for new business and knowledge; yet, exploration is challenging for most large, established firms. Extending prior research into networks and exploration, we propose that a key characteristic of managers’ external netw...

  6. Flow-based Networking and Quality of Service

    NARCIS (Netherlands)

    Kleiberg, T.J.

    2009-01-01

    During the past two decades the Internet has been widely deployed and integrated into the society, radically altering the way people communicate and exchange information. Although the Internet was intended as a research network between few a institutions in the United States, it has grown to take a

  7. Integration of hybrid wireless networks in cloud services oriented enterprise information systems

    Science.gov (United States)

    Li, Shancang; Xu, Lida; Wang, Xinheng; Wang, Jue

    2012-05-01

    This article presents a hybrid wireless network integration scheme in cloud services-based enterprise information systems (EISs). With the emerging hybrid wireless networks and cloud computing technologies, it is necessary to develop a scheme that can seamlessly integrate these new technologies into existing EISs. By combining the hybrid wireless networks and computing in EIS, a new framework is proposed, which includes frontend layer, middle layer and backend layers connected to IP EISs. Based on a collaborative architecture, cloud services management framework and process diagram are presented. As a key feature, the proposed approach integrates access control functionalities within the hybrid framework that provide users with filtered views on available cloud services based on cloud service access requirements and user security credentials. In future work, we will implement the proposed framework over SwanMesh platform by integrating the UPnP standard into an enterprise information system.

  8. A Large Scale Code Resolution Service Network in the Internet of Things

    Directory of Open Access Journals (Sweden)

    Xiangzhan Yu

    2012-11-01

    Full Text Available In the Internet of Things a code resolution service provides a discovery mechanism for a requester to obtain the information resources associated with a particular product code immediately. In large scale application scenarios a code resolution service faces some serious issues involving heterogeneity, big data and data ownership. A code resolution service network is required to address these issues. Firstly, a list of requirements for the network architecture and code resolution services is proposed. Secondly, in order to eliminate code resolution conflicts and code resolution overloads, a code structure is presented to create a uniform namespace for code resolution records. Thirdly, we propose a loosely coupled distributed network consisting of heterogeneous, independent; collaborating code resolution services and a SkipNet based code resolution service named SkipNet-OCRS, which not only inherits DHT’s advantages, but also supports administrative control and autonomy. For the external behaviors of SkipNet-OCRS, a novel external behavior mode named QRRA mode is proposed to enhance security and reduce requester complexity. For the internal behaviors of SkipNet-OCRS, an improved query algorithm is proposed to increase query efficiency. It is analyzed that integrating SkipNet-OCRS into our resolution service network can meet our proposed requirements. Finally, simulation experiments verify the excellent performance of SkipNet-OCRS.

  9. FreeNA: A Multi-Platform Framework for Inserting Upper-Layer Network Services

    Science.gov (United States)

    Kawashima, Ryota; Ji, Yusheng; Maruyama, Katsumi

    Networking technologies have recently been evolving and network applications are now expected to support flexible composition of upper-layer network services, such as security, QoS, or personal firewall. We propose a multi-platform framework called FreeNA that extends existing applications by incorporating the services based on user definitions. This extension does not require users to modify their systems at all. Therefore, FreeNA is valuable for experimental system usage. We implemented FreeNA on both Linux and Microsoft Windows operating systems, and evaluated their functionality and performance. In this paper, we describe the design and implementation of FreeNA including details on how to insert network services into existing applications and how to create services in a multi-platform environment. We also give an example implementation of a service with SSL, a functionality comparison with relevant systems, and our performance evaluation results. The results show that FreeNA offers finer configurability, composability, and usability than other similar systems. We also show that the throughput degradation of transparent service insertion is 2% at most compared with a method of directly inserting such services into applications.

  10. Guidelines for the Management of Acne Vulgaris

    African Journals Online (AJOL)

    Severe seborrhoea (oiliness) – consider more potent face wash. • Check (again) exposure of patient to acne-provoking agents/ drugs. • Check stress and diet – consider lower glycaemic diet. • Check comedogenicity of facial make-up and moisturizing cream – avoid altogether. • Macrocomedones – mechanically remove ...

  11. Hormonal correlates of acne and hirsutism.

    Science.gov (United States)

    Lucky, A W

    1995-01-16

    Acne is a multifactorial disorder reflecting the role of infection, abnormal keratinization and immunologic reaction, as well as hormonal influences, on the pilosebaceous unit. Clinical studies have correlated elevated levels of androgens, originating in both the adrenal glands and ovaries, with acne. These include total and free testosterone, delta 4-androstenedione, dehydroepiandrosterone and its sulfate, and low levels of sex hormone binding globulin. The pathogenesis of acne initiation in childhood has been linked to rising serum levels of dehydroepiandrosterone sulfate. Hirsutism has been more directly correlated with increased levels of serum androgens, notably free testosterone. Underlying causes of elevated androgens in both disorders include very rare tumors, partial or late-onset forms of congenital adrenal hyperplasia, developmental adrenal abnormalities and, most commonly, polycystic ovary syndrome. Early acne treatment may include topical benzoyl peroxide, antibiotics, and tretinoin. More severe disease can be treated systemically (with antibiotics and/or isotretinoin). Very-low-dose corticosteroids can be used to eliminate the adrenal component of hyperandrogenism. Oral contraceptives, especially those that contain low-androgenic progestins, can reduce excessive androgens from any source and specifically suppress the ovary in polycystic ovary syndrome. Gonadotropin-releasing hormone agonists, with or without estrogen supplementation, and systemic or topical antiandrogens may play a more important role in the future.

  12. Global Logistic Network of Courier Services for the 21" Century

    Directory of Open Access Journals (Sweden)

    Ratko Zelenika

    2006-09-01

    Full Text Available The development of logistics has contributed a lot to all thebranches of economy. A successful economic subject cannotexist without a well-developed logistic branch. In economicsthe organization of logistics is becoming a strategic element regardingthe policy making of enterprises. Logistics belongs to anarea that will play an important role in our lives; therefore, thedevelopment of a logistic system is of an exceptional significancefor the economy and also for the non-economic sphere ofactivities. So, modem logistics enables us to bring into line differentinterests in management of material current. Global organizersof logistic services are developing and specializing insome essential services, such as combining of cargo into assemblyconsignments and also their distribution. The biggest globaltenderers of logistic services are considered, DHL, TNT,FEDEX, UPS ...

  13. Service Class Resource Management For Green Wireless-Optical Broadband Access NetworksWOBAN

    Directory of Open Access Journals (Sweden)

    SRUTHY.S

    2015-08-01

    Full Text Available Abstract-Broadband access networks have become an essential part of worldwide communication systems because of the exponential growth of broadband services such as video on demand high definition TV internet protocol TV and video conferencing. Exponential growth in the volume of wireless data boosted by the growing popularity of mobile devices such as smartphone and tablets has forced the telecommunication industries to rethink the way networks are currently designed and to focus on the development of high-capacity mobile broadband networks. In response to this challenge researchers have been working toward the development of an integrated wireless optical broadband access network. Two major candidate technologies which are currently known for their high capacity as well as quality of service QoS for multimedia traffic are passive optical networks PON and fourth generation 4G wireless networks. PON is a wired access technology well known for its cost efficiency and high capacity whereas 4G is a wireless broadband access technology which has achieved broad market acceptance because of its ease of deployment ability to offer mobility and its cost efficiency. Integration of PON and 4G technologies in the form of wireless-optical broadband access networks offers advantages such as extension of networks in rural areas support for mobile broadband services and quick deployment of broadband networks. These two technologies however have different design architectures for handling broadband services that require quality of service. For example 4G networks use traffic classification for supporting different QoS demands whereas the PON architecture has no such mechanism to differentiate between types of traffic. These two technologies also differ in their power saving mechanisms. Propose a service class mapping for the integrated PON-4G network which is based on the MG1 queuing model and class-based power saving mechanism which significantly improves the

  14. Semantics in NETMAR (open service NETwork for MARine environmental data)

    Science.gov (United States)

    Leadbetter, Adam; Lowry, Roy; Clements, Oliver

    2010-05-01

    Over recent years, there has been a proliferation of environmental data portals utilising a wide range of systems and services, many of which cannot interoperate. The European Union Framework 7 project NETMAR (that commenced February 2010) aims to provide a toolkit for building such portals in a coherent manner through the use of chained Open Geospatial Consortium Web Services (WxS), OPeNDAP file access and W3C standards controlled by a Business Process Execution Language workflow. As such, the end product will be configurable by user communities interested in developing a portal for marine environmental data, and will offer search, download and integration tools for a range of satellite, model and observed data from open ocean and coastal areas. Further processing of these data will also be available in order to provide statistics and derived products suitable for decision making in the chosen environmental domain. In order to make the resulting portals truly interoperable, the NETMAR programme requires a detailed definition of the semantics of the services being called and the data which are being requested. A key goal of the NETMAR programme is, therefore, to develop a multi-domain and multilingual ontology of marine data and services. This will allow searches across both human languages and across scientific domains. The approach taken will be to analyse existing semantic resources and provide mappings between them, gluing together the definitions, semantics and workflows of the WxS services. The mappings between terms aim to be more general than the standard "narrower than", "broader than" type seen in the thesauri or simple ontologies implemented by previous programmes. Tools for the development and population of ontologoies will also be provided by NETMAR as there will be instances in which existing resources cannot sufficiently describe newly encountered data or services.

  15. A Method for Assessing Quality of Service in Broadband Networks

    DEFF Research Database (Denmark)

    Bujlow, Tomasz; Riaz, M. Tahir; Pedersen, Jens Myrup

    2012-01-01

    Monitoring of Quality of Service (QoS) in high-speed Internet infrastructure is a challenging task. However, precise assessments must take into account the fact that the requirements for the given quality level are service-dependent. Backbone QoS monitoring and analysis requires processing of large...... and provide C5.0 high-quality training data, divided into groups corresponding to different types of applications. It was found that currently existing means of collecting data (classification by ports, Deep Packet Inspection, statistical classification, public data sources) are not sufficient and they do...

  16. A framework for handling connectionless services in ATM networks

    OpenAIRE

    Abdelati, Mohamed

    1997-01-01

    Ankara : Department of Electrical and Electronics Engineering and the Institute of Engineering and Science of Bilkent University, 1997. Thesis (Ph.D.) -- Bilkent University, 1997. Includes bibliographical references leaves 64-70. ATM networks, which are connection-oriented transport inediums, are well-suited to handle interactive and real-time applications such as telephony and video conferencing. However, they will be underutilized if used directly in aipplications characteriz...

  17. Fast packet switch architectures for broadband integrated services digital networks

    Science.gov (United States)

    Tobagi, Fouad A.

    1990-01-01

    Background information on networking and switching is provided, and the various architectures that have been considered for fast packet switches are described. The focus is solely on switches designed to be implemented electronically. A set of definitions and a brief description of the functionality required of fast packet switches are given. Three basic types of packet switches are identified: the shared-memory, shared-medium, and space-division types. Each of these is described, and examples are given.

  18. Reliability, Availability and Serviceability of Networks-on-Chip

    CERN Document Server

    Cota, Érika; Soares Lubaszewski, Marcelo

    2012-01-01

    This book presents an overview of the issues related to the test, diagnosis and fault-tolerance of Network on Chip-based systems. It is the first book dedicated to the quality aspects of NoC-based systems and will serve as an invaluable reference to the problems, challenges, solutions, and trade-offs related to designing and implementing state-of-the-art, on-chip communication architectures.

  19. Interventions to increase adherence to acne treatment

    Directory of Open Access Journals (Sweden)

    Moradi Tuchayi S

    2016-10-01

    Full Text Available Sara Moradi Tuchayi,1 Tiffany M Alexander,2 Anish Nadkarni,1 Steven R Feldman1,3,4 1Center for Dermatology Research, Department of Dermatology, Wake Forest University School of Medicine, Winston-Salem, NC, 2Howard University College of Medicine, Washington, DC, 3Department of Public Health Sciences, 4Department of Pathology, Wake Forest University School of Medicine, Winston-Salem, NC, USA Background: Adherence to acne medication is poor and is a major reason why treatment plans are ineffective. Recognizing solutions to nonadherence is critical. Objective: The purpose of this study is to describe the hurdles associated with acne nonadherence and to provide mechanisms on how to ameliorate them. Methods: PubMed database was searched. Of the 419 search results, 29 articles were reviewed to identify hurdles to adherence and corresponding solutions. Results: Hurdles to primary nonadherence where the medication is not even started, include lack of knowledge, confusion about usage, weak physician–patient relationship, fear of adverse reactions, and cost. Secondary nonadherence hurdles where the medication is started but is not taken as directed include lack of results, complex regimens, side effects, busy lifestyle, forgetfulness, inconvenience, and psychiatric comorbidity. Solutions to these hurdles include treatment simplification, technology, and dynamic education. Limitations: Adherence is affected by numerous factors, but available literature analyzing acne adherence and interventions to improve adherence to treatment is limited. Conclusion: There are several hurdles in adhering to acne treatment. Recognition of these hurdles and finding appropriate solutions may be as important to treatment outcomes as choosing the right medication to prescribe. Keywords: acne vulgaris, adherence, pathogenesis, treatment, quality of life, prevalence, physician–patient relationship, lifestyle, clinic visit, disease severity

  20. Quality of life in Iranian patients with acne.

    Science.gov (United States)

    Safizadeh, H; Shamsi-Meymandy, S; Naeimi, A

    2012-01-01

    Acne is a chronic inflammatory disease of pilosebaceous units. Although the acne isnot a life threatening disease, studies have revealed that it has significant effect on self-image and quality of life. The purpose of this paper was to investigate the health-related quality of life in patients with acne in an Iranian context. Dermatology Life Quality Index (DLQI) and Cardiff Acne Disability Index (CADI) were used for measuring quality of life, and severity of acne was measured by Global Acne Grading System (GAGS). The mean (±SD) of DLQI and CADI scores was 6.42 (±4.77) and 5.97 (±2.97), respectively. Acne influenced the quality of life in 51.8% of patients from moderate to very much, and the quality of life was affected by the severity of acne (P < 0.01). Since acne has significant effects on patient's quality of life, the management of patients with acne requires more attention to different aspects of quality of life.

  1. Quality of Life in Iranian Patients with Acne

    Directory of Open Access Journals (Sweden)

    H. Safizadeh

    2012-01-01

    Full Text Available Acne is a chronic inflammatory disease of pilosebaceous units. Although the acne isnot a life threatening disease, studies have revealed that it has significant effect on self-image and quality of life. The purpose of this paper was to investigate the health-related quality of life in patients with acne in an Iranian context. Dermatology Life Quality Index (DLQI and Cardiff Acne Disability Index (CADI were used for measuring quality of life, and severity of acne was measured by Global Acne Grading System (GAGS. The mean (±SD of DLQI and CADI scores was 6.42 (±4.77 and 5.97 (±2.97, respectively. Acne influenced the quality of life in 51.8% of patients from moderate to very much, and the quality of life was affected by the severity of acne (P < 0.01. Since acne has significant effects on patient’s quality of life, the management of patients with acne requires more attention to different aspects of quality of life.

  2. Management of Severe Acne Vulgaris With Topical Therapy.

    Science.gov (United States)

    Stein Gold, Linda; Baldwin, Hilary E; Lin, Tina

    2017-11-01

    Acne vulgaris (acne) is the most common skin disease we see in dermatology practice. Although rare in childhood, severe acne can affect up to 12% of the adolescent population. A chronic disease, it requires both aggressive management and effective maintenance strategies. Oral antibiotics, in combination with topical agents are recommended for treatment, with topical agents being continued as maintenance therapy to minimize resistance and recurrence. However, concerns with systemic side effects have recently resulted in a greater focus on the potential of fixed combination topical therapies to treat severe acne. Here we review the available clinical evidence. There are no studies investigating the use of fixed combination topical therapy exclusively in severe acne. However, studies assessing the treatment of moderate-to-severe acne include subpopulation data in severe patients. Adapalene 0.3%-benzoyl peroxide (BP) 2.5% was found to be effective in patients with severe acne, whereas the fixed combination with a lower concentration of adapalene (0.1%) was no more effective than vehicle. Clindamycin-BP 1.2%/3.75% gel and clindamycin-BP 1.2%/2.5% gel were both found to be effective in severe acne with an apparent BP-dose response. Clindamycin phosphate 1.2%-tretinoin 0.025% demonstrated similar efficacy in severe acne, but with little benefit over individual monads. Realistic topical treatment options now exist for the management of severe acne where patient and physician preference can impact positive outcomes. J Drugs Dermatol. 2017;16(11):1134-1138..

  3. Multiple Activities of Punica granatum Linne against Acne Vulgaris

    Directory of Open Access Journals (Sweden)

    Chia-Jung Lee

    2017-01-01

    Full Text Available Acne is a common skin condition with sebum overproduction, hyperkeratosis, Propionibacterium acnes (P. acnes and Staphylococcus aureus, and inflammation. Punica granatum (pomegranate is well-known for its anti-inflammatory effects; however, few studies have discussed the anti-acne effects of pomegranate. In this study, we found that pomegranate extract (PG-E significantly reduced P. acnes-induced edema in Wistar rat ears. Therefore, an evaluation platform using multiple pathogenic mechanisms of acne was established to explore the anti-acne effects of pomegranate. Results showed that PG-E inhibited bacterial growth and lipase activity. Through a bioguided-fractionation-isolation system, four hydrolysable tannins, punicalagin (1, punicalin (2, strictinin A (3, and granatin B (4, were isolated. Compounds 1 and 2 had greater anti-bacterial activities and anti-testosterone-induced HaCaT proliferative effects than the others. Compounds 1, 3, and 4 displayed lipase inhibitory effects. Compound 4 decreased cyclooxygenase-2 expression and downregulated prostaglandin E2 production in heat-killed P. acnes-treated RAW 246.7 cells. In conclusion, PG-E is abundant in hydrolysable tannins that display multiple anti-acne capacities, including anti-bacterial, anti-lipase, anti-keratinocyte proliferation, and anti-inflammatory actions. Hence, PG-E has great potential in the application of anti-acne and skin-care products, and punicalagin (1, the most effective component in PG-E, can be employed as a quality control marker.

  4. Multiple Activities of Punica granatum Linne against Acne Vulgaris

    Science.gov (United States)

    Lee, Chia-Jung; Chen, Lih-Geeng; Liang, Wen-Li; Wang, Ching-Chiung

    2017-01-01

    Acne is a common skin condition with sebum overproduction, hyperkeratosis, Propionibacterium acnes (P. acnes) and Staphylococcus aureus, and inflammation. Punica granatum (pomegranate) is well-known for its anti-inflammatory effects; however, few studies have discussed the anti-acne effects of pomegranate. In this study, we found that pomegranate extract (PG-E) significantly reduced P. acnes-induced edema in Wistar rat ears. Therefore, an evaluation platform using multiple pathogenic mechanisms of acne was established to explore the anti-acne effects of pomegranate. Results showed that PG-E inhibited bacterial growth and lipase activity. Through a bioguided-fractionation-isolation system, four hydrolysable tannins, punicalagin (1), punicalin (2), strictinin A (3), and granatin B (4), were isolated. Compounds 1 and 2 had greater anti-bacterial activities and anti-testosterone-induced HaCaT proliferative effects than the others. Compounds 1, 3, and 4 displayed lipase inhibitory effects. Compound 4 decreased cyclooxygenase-2 expression and downregulated prostaglandin E2 production in heat-killed P. acnes-treated RAW 246.7 cells. In conclusion, PG-E is abundant in hydrolysable tannins that display multiple anti-acne capacities, including anti-bacterial, anti-lipase, anti-keratinocyte proliferation, and anti-inflammatory actions. Hence, PG-E has great potential in the application of anti-acne and skin-care products, and punicalagin (1), the most effective component in PG-E, can be employed as a quality control marker. PMID:28085116

  5. Multiple Activities of Punica granatum Linne against Acne Vulgaris.

    Science.gov (United States)

    Lee, Chia-Jung; Chen, Lih-Geeng; Liang, Wen-Li; Wang, Ching-Chiung

    2017-01-12

    Acne is a common skin condition with sebum overproduction, hyperkeratosis, Propionibacterium acnes (P. acnes) and Staphylococcus aureus, and inflammation. Punica granatum (pomegranate) is well-known for its anti-inflammatory effects; however, few studies have discussed the anti-acne effects of pomegranate. In this study, we found that pomegranate extract (PG-E) significantly reduced P. acnes-induced edema in Wistar rat ears. Therefore, an evaluation platform using multiple pathogenic mechanisms of acne was established to explore the anti-acne effects of pomegranate. Results showed that PG-E inhibited bacterial growth and lipase activity. Through a bioguided-fractionation-isolation system, four hydrolysable tannins, punicalagin (1), punicalin (2), strictinin A (3), and granatin B (4), were isolated. Compounds 1 and 2 had greater anti-bacterial activities and anti-testosterone-induced HaCaT proliferative effects than the others. Compounds 1, 3, and 4 displayed lipase inhibitory effects. Compound 4 decreased cyclooxygenase-2 expression and downregulated prostaglandin E₂ production in heat-killed P. acnes-treated RAW 246.7 cells. In conclusion, PG-E is abundant in hydrolysable tannins that display multiple anti-acne capacities, including anti-bacterial, anti-lipase, anti-keratinocyte proliferation, and anti-inflammatory actions. Hence, PG-E has great potential in the application of anti-acne and skin-care products, and punicalagin (1), the most effective component in PG-E, can be employed as a quality control marker.

  6. Collaborative Service Selection via Ensemble Learning in Mixed Mobile Network Environments

    Directory of Open Access Journals (Sweden)

    Yuyu Yin

    2017-07-01

    Full Text Available Mobile Service selection is an important but challenging problem in service and mobile computing. Quality of service (QoS predication is a critical step in service selection in 5G network environments. The traditional methods, such as collaborative filtering (CF, suffer from a series of defects, such as failing to handle data sparsity. In mobile network environments, the abnormal QoS data are likely to result in inferior prediction accuracy. Unfortunately, these problems have not attracted enough attention, especially in a mixed mobile network environment with different network configurations, generations, or types. An ensemble learning method for predicting missing QoS in 5G network environments is proposed in this paper. There are two key principles: one is the newly proposed similarity computation method for identifying similar neighbors; the other is the extended ensemble learning model for discovering and filtering fake neighbors from the preliminary neighbors set. Moreover, three prediction models are also proposed, two individual models and one combination model. They are used for utilizing the user similar neighbors and servicing similar neighbors, respectively. Experimental results conducted in two real-world datasets show our approaches can produce superior prediction accuracy.

  7. A multimodal logistics service network design with time windows and environmental concerns.

    Directory of Open Access Journals (Sweden)

    Dezhi Zhang

    Full Text Available The design of a multimodal logistics service network with customer service time windows and environmental costs is an important and challenging issue. Accordingly, this work established a model to minimize the total cost of multimodal logistics service network design with time windows and environmental concerns. The proposed model incorporates CO2 emission costs to determine the optimal transportation mode combinations and investment selections for transfer nodes, which consider transport cost, transport time, carbon emission, and logistics service time window constraints. Furthermore, genetic and heuristic algorithms are proposed to set up the abovementioned optimal model. A numerical example is provided to validate the model and the abovementioned two algorithms. Then, comparisons of the performance of the two algorithms are provided. Finally, this work investigates the effects of the logistics service time windows and CO2 emission taxes on the optimal solution. Several important management insights are obtained.

  8. A multimodal logistics service network design with time windows and environmental concerns.

    Science.gov (United States)

    Zhang, Dezhi; He, Runzhong; Li, Shuangyan; Wang, Zhongwei

    2017-01-01

    The design of a multimodal logistics service network with customer service time windows and environmental costs is an important and challenging issue. Accordingly, this work established a model to minimize the total cost of multimodal logistics service network design with time windows and environmental concerns. The proposed model incorporates CO2 emission costs to determine the optimal transportation mode combinations and investment selections for transfer nodes, which consider transport cost, transport time, carbon emission, and logistics service time window constraints. Furthermore, genetic and heuristic algorithms are proposed to set up the abovementioned optimal model. A numerical example is provided to validate the model and the abovementioned two algorithms. Then, comparisons of the performance of the two algorithms are provided. Finally, this work investigates the effects of the logistics service time windows and CO2 emission taxes on the optimal solution. Several important management insights are obtained.

  9. NetworkTrail--a web service for identifying and visualizing deregulated subnetworks.

    Science.gov (United States)

    Stöckel, Daniel; Müller, Oliver; Kehl, Tim; Gerasch, Andreas; Backes, Christina; Rurainski, Alexander; Keller, Andreas; Kaufmann, Michael; Lenhof, Hans-Peter

    2013-07-01

    The deregulation of biochemical pathways plays a central role in many diseases like cancer or Parkinsons's disease. In silico tools for calculating these deregulated pathways may help to gain new insights into pathogenic mechanisms and may open novel avenues for therapy stratification in the sense of personalized medicine. Here, we present NetworkTrail, a web service for the detection of deregulated pathways and subgraphs in biological networks. NetworkTrail uses a state-of-the-art integer linear programming-based approach for this task and offers interfaces to the Biological Network Analyzer (BiNA) and Cytoscape Web for visualizing the resulting subnetworks. By providing an accessible interface to otherwise hard-to-use command line tools, the new web service enables non-experts to quickly and reliably carry out this type of network analyses. NetworkTrail is a JavaServer Pages-based web service. The algorithm for finding deregulated subnetworks has been implemented in C++. NetworkTrail is available at http://networktrail.bioinf.uni-sb.de/.

  10. DECENTRALIZED SOCIAL NETWORK SERVICE USING THE WEB HOSTING SERVER FOR PRIVACY PRESERVATION

    Directory of Open Access Journals (Sweden)

    Yoonho Nam

    2013-10-01

    Full Text Available In recent years, the number of subscribers of the social network services such as Facebook and Twitter has increased rapidly. In accordance with the increasing popularity of social network services, concerns about user privacy are also growing. Existing social network services have a centralized structure that a service provider collects all the user’s profile and logs until the end of the connection. The information collected typically useful for commercial purposes, but may lead to a serious user privacy violation. The user’s profile can be compromised for malicious purposes, and even may be a tool of surveillance extremely. In this paper, we remove a centralized structure to prevent the service provider from collecting all users’ information indiscriminately, and present a decentralized structure using the web hosting server. The service provider provides only the service applications to web hosting companies, and the user should select a web hosting company that he trusts. Thus, the user’s information is distributed, and the user’s privacy is guaranteed from the service provider.

  11. Networking Our Way to Better Ecosystem Service Provision

    NARCIS (Netherlands)

    Braak, ter C.J.F.

    2016-01-01

    The ecosystem services (EcoS) concept is being used increasingly to attach values to natural systems and the multiple benefits they provide to human societies. Ecosystem processes or functions only become EcoS if they are shown to have social and/or economic value. This should assure an explicit

  12. Power Efficient Service Differentiation Based on Traffic-Aware Survivable Elastic Optical Networks

    DEFF Research Database (Denmark)

    Turus, Ioan; Fagertun, Anna Manolova; Dittmann, Lars

    2014-01-01

    This study assesses the feasible energy savings whendefining different service classes based on protection schemesincore optical networks.Wepropose a dedicated energy savingstrategy for each of the service classes in order to minimize theoverall power consumption of the network.Four Classes of Se...... while for the proposed approach the difference in power consumption is almost negligible.Moreover, incase of the proposed approach,silver serviceclass can benefit for superior quality of service compared to the gold service class, due to the grooming mechanism.......This study assesses the feasible energy savings whendefining different service classes based on protection schemesincore optical networks.Wepropose a dedicated energy savingstrategy for each of the service classes in order to minimize theoverall power consumption of the network.Four Classes...... of Serviceareconsidered: platinum, gold, silver and best effort.Platinumconnections benefit from a 1+1 protection scheme, gold connections and silver connections are assigned to a 1:1 protection with the difference that in case of gold connections the same pair of transponders is shared by the working and protection...

  13. Analysis of Complete Genomes of Propionibacterium acnes Reveals a Novel Plasmid and Increased Pseudogenes in an Acne Associated Strain

    Directory of Open Access Journals (Sweden)

    Gabriela Kasimatis

    2013-01-01

    Full Text Available The human skin harbors a diverse community of bacteria, including the Gram-positive, anaerobic bacterium Propionibacterium acnes. P. acnes has historically been linked to the pathogenesis of acne vulgaris, a common skin disease affecting over 80% of all adolescents in the US. To gain insight into potential P. acnes pathogenic mechanisms, we previously sequenced the complete genome of a P. acnes strain HL096PA1 that is highly associated with acne. In this study, we compared its genome to the first published complete genome KPA171202. HL096PA1 harbors a linear plasmid, pIMPLE-HL096PA1. This is the first described P. acnes plasmid. We also observed a five-fold increase of pseudogenes in HL096PA1, several of which encode proteins in carbohydrate transport and metabolism. In addition, our analysis revealed a few island-like genomic regions that are unique to HL096PA1 and a large genomic inversion spanning the ribosomal operons. Together, these findings offer a basis for understanding P. acnes virulent properties, host adaptation mechanisms, and its potential role in acne pathogenesis at the strain level. Furthermore, the plasmid identified in HL096PA1 may potentially provide a new opportunity for P. acnes genetic manipulation and targeted therapy against specific disease-associated strains.

  14. Clinical studies of the treatment of facial atrophic acne scars and acne with a bipolar fractional radiofrequency system.

    Science.gov (United States)

    Kaminaka, Chikako; Uede, Mikiko; Matsunaka, Hiroshi; Furukawa, Fukumi; Yamamoto, Yuki

    2015-06-01

    Few clinical studies have examined the utility of bipolar fractional radiofrequency (FRF) therapy as a treatment for atrophic acne scars and active acne in people with darker skin. This study was designed to compare the safety and efficacy of bipolar FRF therapy as a treatment for atrophic acne scars and acne vulgaris. Twenty-three Japanese patients with atrophic acne scars and mild to severe acne on both cheeks were treated with a bipolar FRF system (eMatrix; Syneron, Yokneam Illit, Israel). Five treatment sessions were carried out at 1-month intervals, and the patients were followed up for 3 months after the final treatment. Assessments of scar severity and the number of acne lesions and 3-D in vivo imaging analysis were performed. Evaluations of the treatment outcomes and their effects on the patients' quality of life (QOL) were also carried out. We demonstrated that the improvement in scar volume was marked in the patients with mild scars and was at least moderate in 23 (57.5%) of the treated areas. With regard to the number of acne lesions, the treated areas exhibited significantly fewer lesions compared with the baseline at each time point (P scar depth were observed. Bipolar FRF treatment significantly improved the atrophic acne scars and acne of Japanese patients and had minimal side-effects. © 2015 Japanese Dermatological Association.

  15. Concomitant use of an infrared fractional laser with low-dose isotretinoin for the treatment of acne and acne scars.

    Science.gov (United States)

    Yoon, Jong Hyun; Park, Eun Joo; Kwon, In Ho; Kim, Chul Woo; Lee, Geun Soo; Hann, Seung Kyung; Kim, Kwang Ho; Kim, Kwang Joong

    2014-04-01

    Acne scarring has lifelong sequelae. Fractional photothermolysis (FP) has been shown to provide fast recovery from acne within a short period, thereby aiding skin rejuvenation. Isotretinoin is a well-known, effective drug for the treatment of severe recalcitrant acne. This study investigated the safety and the efficacy of infrared fractional laser treatment in conjunction with low-dose isotretinoin for the treatment of acne and acne scars. A 1550 nm Erbium-doped fiber laser was used to treat 35 patients with acne scarring. All the patients had taken isotretinoin (10 mg/day) for more than one month prior to the commencement of the fractional laser treatment. There was no aggravation of acne scars, hypertrophic scars, or keloids. Most of the patients (33 patients) received reduced microthermal damage zone (MTZ) treatment. Eighty percent of the treated patients (28 patients) demonstrated more than a fair improvement. The total average score on the global acne scarring classification before treatment was 13.5, and the score after treatment was 11.2. Acne and acne scars can be treated more effectively by concomitant use of an infrared fractional laser with low-dose isotretinoin with reduced MTZ densities. Most patients showed more than a fair improvement, and there was no aggravation of the scars.

  16. Method and system for a network mapping service

    Energy Technology Data Exchange (ETDEWEB)

    Bynum, Leo

    2017-10-17

    A method and system of publishing a map includes providing access to a plurality of map data files or mapping services between at least one publisher and at least one subscriber; defining a map in a map context comprising parameters and descriptors to substantially duplicate a map by reference to mutually accessible data or mapping services, publishing a map to a channel in a table file on server; accessing the channel by at least one subscriber, transmitting the mapping context from the server to the at least one subscriber, executing the map context by the at least one subscriber, and generating the map on a display software associated with the at least one subscriber by reconstituting the map from the references and other data in the mapping context.

  17. INCAS—Interactive Teleconsultation Network for Worldwide Healthcare Services

    Science.gov (United States)

    Castelli, A.; Colombo, C.; Garlaschelli, A.; Pepe, G.

    2001-01-01

    The INCAS Project arises from the needs of an Italian oil company in order to support the doctors responsible for the healthcare in remote drilling sites. The INCAS telemedicine1 system implements a prototype of teleconsultation medical service allowing for the interactive on-line connection with Italian healthcare reference centres in order to: • provide support to the expatriate doctor with the diagnoses and treatment of routine complaints; • contribute to the general improvement of healthcare in remote areas.

  18. Towards Horizontal Architecture for Autonomic M2M Service Networks

    Directory of Open Access Journals (Sweden)

    Juhani Latvakoski

    2014-05-01

    Full Text Available Today, increasing number of industrial application cases rely on the Machine to Machine (M2M services exposed from physical devices. Such M2M services enable interaction of physical world with the core processes of company information systems. However, there are grand challenges related to complexity and “vertical silos” limiting the M2M market scale and interoperability. It is here expected that horizontal approach for the system architecture is required for solving these challenges. Therefore, a set of architectural principles and key enablers for the horizontal architecture have been specified in this work. A selected set of key enablers called as autonomic M2M manager, M2M service capabilities, M2M messaging system, M2M gateways towards energy constrained M2M asset devices and creation of trust to enable end-to-end security for M2M applications have been developed. The developed key enablers have been evaluated separately in different scenarios dealing with smart metering, car sharing and electric bike experiments. The evaluation results shows that the provided architectural principles, and developed key enablers establish a solid ground for future research and seem to enable communication between objects and applications, which are not initially been designed to communicate together. The aim as the next step in this research is to create a combined experimental system to evaluate the system interoperability and performance in a more detailed manner.

  19. Coordinated system services from offshore wind power plants connected through HVDC networks

    DEFF Research Database (Denmark)

    Zeni, Lorenzo; Glasdam, Jakob; Hesselbæk, Bo

    2014-01-01

    control and communication delays of OWPPs, and their influence on the successful delivery of the targeted services. Furthermore, it is shown that as an HVDC network increases in size from the point-to-point, the handling of onshore short circuits calls for the proper combination of DC chopper(s) and fast......, its combination with OWPPs, against a conventional power station of comparable size. Consequently it will be pointed out what features will be critical for TSOs when partially or completely replacing conventional units with HVDC stations connected to neighbouring systems and/or OWPPs.......This paper presents an overview of power system services in networks involving multiple onshore power systems, a voltage sourced converter (VSC) based high voltage direct current (HVDC) offshore network and an offshore wind power plant (OWPP). A comprehensive list of services regarding onshore...

  20. OptoVisor: an infrastructure-as-a-service framework based on virtualization of optical network

    Science.gov (United States)

    Zuo, Xiaosheng; Feng, Yifei; Jin, Yaohui

    2011-12-01

    In the field of cloud computing over optical networks, virtualization is an important issue. Typically this can be implemented on hardware or software. In this paper, we propose an infrastructure-as-a-service (IaaS) framework-OptoVisor, with optical network virtualization implemented on management plane. This framework provides flexible resource scheduling and monitoring. Then we show the viability of our proposal with experimental demonstration and performance test.

  1. Provision of QoS for Multimedia Services in IEEE 802.11 Wireless Network

    Science.gov (United States)

    2006-10-01

    INFORMATION SYSTEMS TECHNOLOGY PANEL SYMPOSIUM ON „DYNAMIC COMUNICATIONS MANAGEMENT ” IST-062 October 9 - 10, 2006 Piotr Lubkowski, Jaroslaw Krygier...Provision of QoS for Multimedia Services in IEEE 802.11 Wireless Network. In Dynamic Communications Management (pp. 10-1 – 10-16). Meeting Proceedings...mechanisms have been used for managing a limited bandwidth link within the IPv6 military narrowband network. The detailed description of these

  2. Network Location-Aware Service Recommendation with Random Walk in Cyber-Physical Systems.

    Science.gov (United States)

    Yin, Yuyu; Yu, Fangzheng; Xu, Yueshen; Yu, Lifeng; Mu, Jinglong

    2017-09-08

    Cyber-physical systems (CPS) have received much attention from both academia and industry. An increasing number of functions in CPS are provided in the way of services, which gives rise to an urgent task, that is, how to recommend the suitable services in a huge number of available services in CPS. In traditional service recommendation, collaborative filtering (CF) has been studied in academia, and used in industry. However, there exist several defects that limit the application of CF-based methods in CPS. One is that under the case of high data sparsity, CF-based methods are likely to generate inaccurate prediction results. In this paper, we discover that mining the potential similarity relations among users or services in CPS is really helpful to improve the prediction accuracy. Besides, most of traditional CF-based methods are only capable of using the service invocation records, but ignore the context information, such as network location, which is a typical context in CPS. In this paper, we propose a novel service recommendation method for CPS, which utilizes network location as context information and contains three prediction models using random walking. We conduct sufficient experiments on two real-world datasets, and the results demonstrate the effectiveness of our proposed methods and verify that the network location is indeed useful in QoS prediction.

  3. [Sociability networks: approaches based on home-based therapeutic care services].

    Science.gov (United States)

    Argiles, Carmen Terezinha Leal; Kantorski, Luciane Prado; Willrich, Janaína Quinzen; Antonacci, Milena Hohmann; Coimbra, Valéria Cristina Christello

    2013-07-01

    Home-based therapeutic services emerge in the context of psychiatric reform in Brazil, as a step forward in the policy of de-institutionalization, as well as being essential services to overcome custody practices, typical of the asylum model. These services provide spaces for care, welcome and decent housing for people whose family and social ties have been affected by internment in psychiatric hospitals. The article seeks to evaluate the sociability network of users of home-based therapeutic services in Alegrete in the State of Rio Grande do Sul, based on a case report. This study is part of the research on 'Networks that Rehabilitate'--evaluating innovative experiments in the composition of psychosocial care networks. Data from semi-structured interviews with the six workers of the service were used. It was observed that the service provides unique and innovative experience to find solutions that bring people with long periods of psychiatric hospitalization back together with their family, the community and city life, thereby eliminating the segregation to which they were subjected. Coaching residents and workers in the creation of home-based therapeutic care services reveals the potential to reintegrate mentally handicapped patients into society.

  4. Energy-Based Devices in Treatment of Acne Vulgaris.

    Science.gov (United States)

    Handler, Marc Z; Bloom, Bradley S; Goldberg, David J

    2016-05-01

    Acne vulgaris is a chronic dermatologic complaint with a multifactorial cause. Traditionally, antibiotics and retinoids have been used to manage the condition; patient compliance has been an ongoing issue. A variety of energy-based devices have been reported to be effective in the treatment of acne vulgaris. To review and summarize the current literature specific to treatment of acne vulgaris with energy-based devices. A review of the current literature of energy-based devices used for the treatment of acne vulgaris. Although limited randomized controlled trials for the treatment of acne have been performed, significant clinical improvement of acne vulgaris, especially of inflammatory lesions, has been demonstrated with a variety of energy-based devices. Newer approaches may lead to even better results.

  5. Formulation and evaluation of herbal anti-acne moisturizer.

    Science.gov (United States)

    Rasheed, Arun; Shama, Shaik Neelufar; Joy, Jyothi Mulanjananiyil; Reddy, Bobbu Sravya; Roja, Chirra

    2012-10-01

    The moisture content present in human skin makes it look young and the use of moisturizer results in fastening the moisture with a surface film of oil. Acne vulgaris is one of the most commonly seen diseases among the youth. The present study is focused on the use of herbs as moisturizer for acne treatment. The anti-acne moisturizer was formulated from herbal crude extracts and investigated the physico-chemical parameters as well as antibacterial activity of the formulation. The study revealed that ethanol extract of Andrographis paniculata, Glycyrrhiza glabra, Ocimum sanctum, Azadiracta indica and Green tea possessed the potential for inhibiting acne. It was observed that the optimal formula of anti-acne moisturizer was satisfactorily effective to control acne inducing bacteria i.e., Staphylococcus epidermis and Propionibacterium. The physico-chemical parameters of the formulation were also optimal with no signs of irritation.

  6. Quantifying the quality of service of streaming media in differentiated services networks

    NARCIS (Netherlands)

    Agrawal, D.K.; Kleiberg, T.; Papp, S.; Kooij, R.E.; Mieghem, P. van

    2007-01-01

    Quality of Service (QoS) support in the current internet is indispensable because of QoS-sensitive real-time applications such as Voice-over-IP, IP-TV, video conferencing, online gaming etc. Since the introduction of the Differentiated Services (Diff-Serv) architecture there has been considerable

  7. Quantifying the Quality of Service of Streaming Media in Differentiated Services Networks

    NARCIS (Netherlands)

    Agrawal, D.K.; Kleiberg, T.; Papp, S.; Kooij, R.E.; Van Mieghem, P.

    2007-01-01

    Quality of Service (QoS) support in the current internet is indispensable because of QoS-sensitive real-time applications such as Voice-over-IP, IP-TV, video conferencing, online gaming etc. Since the introduction of the Differentiated Services (Diff-Serv) architecture there has been considerable

  8. Small Faith-Related Organizations as Partners in Local Social Service Networks

    Directory of Open Access Journals (Sweden)

    David Campbell

    2016-05-01

    Full Text Available Efforts to enlist small faith-related organizations as partners in public service delivery raise many questions. Using community social service networks as the unit of analysis, this paper asks one with broader relevance to nonprofit sector managers: What factors support and constrain effective integration of these organizations into a local service delivery network? The evidence and illustrations come from longitudinal case studies of five faith-related organizations who received their first government contract as part of a California faith-based initiative. By comparing the organizational development and network partnership trajectories of these organizations over more than a decade, the analysis identifies four key variables influencing partnership dynamics and outcomes: organizational niche within the local network; leadership connections and network legitimacy; faith-inspired commitments and persistence; and core organizational competencies and capacities. The evidence supports shifting the focus of faith-based initiatives to emphasize local planning and network development, taking into account how these four variables apply to specific organizations and their community context.

  9. Study of the full-service and low-cost carriers network configuration

    Directory of Open Access Journals (Sweden)

    Oriol Lordan

    2014-10-01

    Full Text Available Purpose: The network strategies used by airline carriers have been a recurring subject in air transport research. The aim of this paper is to investigate the relationship between the different operational characteristics of the airline and its route network configuration. Design/methodology/approach: The two main airline carrier typologies - Full-Service and Low-Cost carriers – are analysed using empirical models developed on complex network research relating them to the business model of the airlines. Findings and Originality/value: Just in Europe, one can differentiate between Full-Service and Low-Cost Carriers by complex network analyses. In this process, it has been also found that new concept Low-Cost Carriers, such as Vueling, have network properties closer to Full-Service Carriers. Research limitations/implications: This paper has a limited sample, as includes 26 airline case studies from Europe, United States and Asia. Practical implications: The analysis carried out in this research can help to the assessment of the evolution of the strategies of airline carriers, and has also operational implications, since the configuration of an airline route network can determine its resilience to attacks and errors. Social implications: A better understanding of the properties of airline route networks can benefit airlines, passengers and another stakeholders of the air transport industry. Originality/value: Current research on air transport networks has only considered the global or regional level, but few studies have addressed the study of airline transport networks, and its relationship with their business model.

  10. Optimal Dimensioning of Broadband Integrated Services Digital Network

    Directory of Open Access Journals (Sweden)

    Zdenka Chmelikova

    2005-01-01

    Full Text Available Tasks of this paper are research of input flow statistic parametres influence and parameters demands relating to VP (Virtual Path or VC (Virtual Channel dimensioning. However it is necessary to consider different time of flow arrival and differend time of holding time during connection level. Process of input flow arrival is considered as Poisson process. Holding time is considered as exponential function. Permanent allocation of VP is made by separate VP, where each of VPs enable transmitting offered laod with explicit bandwidth and explicit loss. The mathematic model was created to verify the above mentioned dependences for different types of telecomunications signals and different input flows. "Comnet III" software was selected for experimental verification of process optimization. The simulation model was based on thiss software, which simulate ATM network traffic in behalf of different input flow.

  11. A Honey Trap for the Treatment of Acne: Manipulating the Follicular Microenvironment to Control Propionibacterium acnes

    Directory of Open Access Journals (Sweden)

    E. Anne Eady

    2013-01-01

    Full Text Available Today, as 40 years ago, we still rely on a limited number of antibiotics and benzoyl peroxide to treat inflammatory acne. An alternative way of suppressing the growth of Propionibacterium acnes is to target the environment in which it thrives. We conjecture that P. acnes colonises a relatively “extreme” habitat especially in relation to the availability of water and possibly related factors such as ionic strength and osmolarity. We hypothesise that the limiting “nutrient” within pilosebaceous follicles is water since native sebum as secreted by the sebaceous gland contains none. An aqueous component must be available within colonised follicles, and water may be a major factor determining which follicles can sustain microbial populations. One way of preventing microbial growth is to reduce the water activity ( of this component with a biocompatible solute of very high water solubility. For the method to work effectively, the solute must be small, easily diffusible, and minimally soluble in sebaceous lipids. Xylose and sucrose, which fulfil these criteria, are nonfermentable by P. acnes and have been used to reduce water activity and hence bacterial colonisation of wounds. A new follicularly targeted topical treatment for acne based on this approach should be well tolerated and highly effective.

  12. A managed clinical network for cardiac services: set-up, operation and impact on patient care

    Directory of Open Access Journals (Sweden)

    Karen E. Hamilton

    2005-09-01

    Full Text Available Purpose: To investigate the set up and operation of a Managed Clinical Network for cardiac services and assess its impact on patient care. Methods: This single case study used process evaluation with observational before and after comparison of indicators of quality of care and costs. The study was conducted in Dumfries and Galloway, Scotland and used a three-level framework. Process evaluation of the network set-up and operation through a documentary review of minutes; guidelines and protocols; transcripts of fourteen semi-structured interviews with health service personnel including senior managers, general practitioners, nurses, cardiologists and members of the public. Outcome evaluation of the impact of the network through interrupted time series analysis of clinical data of 202 patients aged less than 76 years admitted to hospital with a confirmed myocardial infarction one-year pre and one-year post, the establishment of the network. The main outcome measures were differences between indicators of quality of care targeted by network protocols. Economic evaluation of the transaction costs of the set-up and operation of the network and the resource costs of the clinical care of the 202 myocardial infarction patients from the time of hospital admission to 6 months post discharge through interrupted time series analysis. The outcome measure was different in National Health Service resource use. Results: Despite early difficulties, the network was successful in bringing together clinicians, patients and managers to redesign services, exhibiting most features of good network management. The role of the energetic lead clinician was crucial, but the network took time to develop and ‘bed down’. Its primary “modus operand” was the development of a myocardial infarction pathway and associated protocols. Of sixteen clinical care indicators, two improved significantly following the launch of the network and nine showed improvements, which were

  13. Implementation of Guaranteed Services in the MANGO Clockless Network-on-Chip

    DEFF Research Database (Denmark)

    Bjerregaard, Tobias; Sparsø, Jens

    2006-01-01

    Shared, segmented, on-chip interconnection networks, known as networks-on-chip (NoC), may become the preferred way of interconnecting intellectual property (IP) cores in future giga-scale system-on-chip (SoC) designs. A NoC can provide the required communication bandwidth while accommodating...... the effects of scaling microchip technologies. Equally important, a NoC facilitates a truly modular and scalable design flow. The MANGO (message-passing asynchronous network-on-chip providing guaranteed services over open core protocol (OCP) interfaces) NoC is presented, and how its key characteristics...

  14. A managed clinical network for cardiac services: set-up, operation and impact on patient care

    Science.gov (United States)

    E StC Hamilton, Karen; M Sullivan, Frank; T Donnan, Peter; Taylor, Rex; Ikenwilo, Divine; Scott, Anthony; Baker, Chris; Wyke, Sally

    2005-01-01

    Abstract Purpose To investigate the set up and operation of a Managed Clinical Network for cardiac services and assess its impact on patient care. Methods This single case study used process evaluation with observational before and after comparison of indicators of quality of care and costs. The study was conducted in Dumfries and Galloway, Scotland and used a three-level framework. Process evaluation of the network set-up and operation through a documentary review of minutes; guidelines and protocols; transcripts of fourteen semi-structured interviews with health service personnel including senior managers, general practitioners, nurses, cardiologists and members of the public. Outcome evaluation of the impact of the network through interrupted time series analysis of clinical data of 202 patients aged less than 76 years admitted to hospital with a confirmed myocardial infarction one-year pre and one-year post, the establishment of the network. The main outcome measures were differences between indicators of quality of care targeted by network protocols. Economic evaluation of the transaction costs of the set-up and operation of the network and the resource costs of the clinical care of the 202 myocardial infarction patients from the time of hospital admission to 6 months post discharge through interrupted time series analysis. The outcome measure was different in National Health Service resource use. Results Despite early difficulties, the network was successful in bringing together clinicians, patients and managers to redesign services, exhibiting most features of good network management. The role of the energetic lead clinician was crucial, but the network took time to develop and ‘bed down’. Its primary “modus operand” was the development of a myocardial infarction pathway and associated protocols. Of sixteen clinical care indicators, two improved significantly following the launch of the network and nine showed improvements, which were not

  15. Analysis and Optimization of Sparse Random Linear Network Coding for Reliable Multicast Services

    DEFF Research Database (Denmark)

    Tassi, Andrea; Chatzigeorgiou, Ioannis; Roetter, Daniel Enrique Lucani

    2016-01-01

    techniques, and without any assumption on the implementation of the RLNC decoder in use, we provide an efficient way to characterize the performance of users targeted by ultra-reliable layered multicast services. The proposed modeling allows to efficiently derive the average number of coded packet...... transmissions needed to recover one or more service layers. We design a convex resource allocation framework that allows to minimize the complexity of the RLNC decoder by jointly optimizing the transmission parameters and the sparsity of the code. The designed optimization framework also ensures service......Point-to-multipoint communications are expected to play a pivotal role in next-generation networks. This paper refers to a cellular system transmitting layered multicast services to a multicast group of users. Reliability of communications is ensured via different random linear network coding (RLNC...

  16. Quality-of-service control in GRAMS for ATM local area network

    Science.gov (United States)

    Hui, Joseph Y.; Zhang, Junbiao; Li, Jun

    1995-05-01

    Gopher-style real-time ATM multimedia services (GRAMS) is a system designed for an ATM local area network, with the server providing multimedia services to multiple users in real-time, while the network bandwidth and the host capacity are fully exploited. Therefore, a server that can determine the service rates, and successfully multiplex media transmissions according to the quality-of-service (QoS) requirement of each request is a key component of this system. Proposed in this paper is a simple yet effective way to measure QoS in the GRAMS system. Experimental results are also presented, showing the feasibility of simultaneously providing tens of video and image transfer sessions using low-cost workstation technology.

  17. Resource management for multimedia services in high data rate wireless networks

    CERN Document Server

    Zhang, Ruonan; Pan, Jianping

    2017-01-01

    This brief offers a valuable resource on principles of quality-of-service (QoS) provisioning and the related link-layer resource management techniques for high data-rate wireless networks. The primary emphasis is on protocol modeling and analysis. It introduces media access control (MAC) protocols, standards of wireless local area networks (WLANs), wireless personal area networks (WPANs), and wireless body area networks (WBANs), discussing their key technologies, applications, and deployment scenarios. The main analytical approaches and models for performance analysis of the fundamental resource scheduling mechanisms, including the contention-based, reservation-based, and hybrid MAC, are presented. To help readers understand and evaluate system performance, the brief contains a range of simulation results. In addition, a thorough bibliography provides an additional tool. This brief is an essential resource for engineers, researchers, students, and users of wireless networks.

  18. Intelligent Networks Data Fusion Web-based Services for Ad-hoc Integrated WSNs-RFID

    Directory of Open Access Journals (Sweden)

    Falah Alshahrany

    2016-01-01

    Full Text Available The use of variety of data fusion tools and techniques for big data processing poses the problem of the data and information integration called data fusion having objectives which can differ from one application to another. The design of network data fusion systems aimed at meeting these objectives, need to take into account of the necessary synergy that can result from distributed data processing within the data networks and data centres, involving increased computation and communication. This papers reports on how this processing distribution is functionally structured as configurable integrated web-based support services, in the context of an ad-hoc wireless sensor network used for sensing and tracking, in the context of distributed detection based on complete observations to support real rime decision making. The interrelated functional and hardware RFID-WSN integration is an essential aspect of the data fusion framework that focuses on multi-sensor collaboration as an innovative approach to extend the heterogeneity of the devices and sensor nodes of ad-hoc networks generating a huge amount of heterogeneous soft and hard raw data. The deployment and configuration of these networks require data fusion processing that includes network and service management and enhances the performance and reliability of networks data fusion support systems providing intelligent capabilities for real-time control access and fire detection.

  19. Role of insulin resistance and diet in acne

    Directory of Open Access Journals (Sweden)

    Rashmi Kumari

    2013-01-01

    Full Text Available There is increasing evidence in support of the interplay of growth hormone (GH, insulin, and insulin-like growth factor-1 (IGF-1 signaling during puberty, which have a causal role in pathogenesis of acne by influencing adrenal and gonadal androgen metabolism. Milk consumption and hyperglycemic diets can induce insulin and IGF-1-mediated PI3K ⁄ Akt-activation inducing sebaceous lipogenesis, sebocyte, and keratinocyte proliferation, which can aggravate acne. Occurence of acne as part of various syndromes also provides evidence in favor of correlation between IGF-1 and acne.

  20. A review of adapalene in the treatment of acne vulgaris.

    Science.gov (United States)

    Irby, Cynthia E; Yentzer, Brad A; Feldman, Steven R

    2008-11-01

    Topical retinoids help address the early lesions of acne vulgaris. Consensus guidelines advocate the use of topical retinoids as the primary treatment for most forms of acne vulgaris. However, all topical retinoid preparations may be irritating, and this may contribute to underutilization in clinical practices. Topical adapalene fosters topical retinoid treatment of acne with less irritation. Adapalene is a more stable molecule than tretinoin. Adapalene can be used without concern for photo-deactivation. Because of its chemical stability, adapalene can be used in combination with benzoyl peroxide products. The availability of a stable topical retinoid associated with little irritation may facilitate meeting acne treatment consensus guidelines.

  1. Acne vulgaris and well-being in medical students

    OpenAIRE

    Jonas Ribas; Cláudia Marina P. B. Oliveira

    2008-01-01

    FUNDAMENTOS - Observa-se comorbidade psiquiátrica em 40% dos pacientes dermatológicos adultos, sendo a acne vulgar de interesse da psicodermatologia por ter entre suas complicações seqüelas psicossociais. OBJETIVOS - Estabelecer a relação entre acne e o status de bem-estar. MÉTODOS - Estudo de caso-controle com dados coletados a partir do Índice de Bem-Estar da Organização Mundial da Saúde, por meio de entrevistas com dois grupos de 50 acadêmicos de medicina, sendo um com acne e outro sem acn...

  2. Practical Evaluation and Management of Atrophic Acne Scars

    Science.gov (United States)

    2011-01-01

    Atrophic acne scarring is an unfortunate, permanent complication of acne vulgaris, which may be associated with significant psychological distress. General dermatologists are frequently presented with the challenge of evaluating and providing treatment recommendations to patients with acne scars. This article reviews a practical, step-by-step approach to evaluating the patient with atrophic acne scars. An algorithm for providing treatment options is presented, along with pitfalls to avoid. A few select procedures that may be incorporated into a general dermatology practice are reviewed in greater detail, including filler injections, skin needling, and the punch excision. PMID:21909457

  3. The Effectiveness of Benzoyl Peroxide 5% Gel with 0.05% Tretinoin Gel in Patients with Mild Acne Vulgaris (Identification of P. Acnes)

    OpenAIRE

    Farida Tabri, Farida Tabri

    2016-01-01

    - Abstract: Topical tretinoin is used by the dermatolovenereologist and aesthetic physicians in patients with mild acne vulgaris, so it is necessary to be investigated. The aim of the study was to assess the effectiveness of benzoyl peroxide gel compared to tretinoin gel on persons with mild acne vulgaris and identify Propionibacterium acnes in patients with mild acne vulgaris. The research method was a clinical trial, double blind randomization. Patients with mild acne vulgaris were rando...

  4. Deployment of pHealth Services upon Always Best Connected Next Generation Network

    OpenAIRE

    Athanasiou, Georgia; Lymberopoulos, Dimitrios,

    2012-01-01

    Part 1: Second Artificial Intelligence Applications in Biomedicine Workshop (AIAB 2012); International audience; This paper deals with the deployment of personalized healthcare (pHealth) services upon new networks supporting pervasive connectivity. A profiling scheme of two levels is introduced, where health status related attributes and preferences are included in the upper-level, named Service User Profile and communication attributes compose the lower-level, named Transport User Profiles. ...

  5. Max-Min Optimality of Service Rate Control in Closed Queueing Networks

    KAUST Repository

    Xia, Li

    2013-04-01

    In this technical note, we discuss the optimality properties of service rate control in closed Jackson networks. We prove that when the cost function is linear to a particular service rate, the system performance is monotonic w.r.t. (with respect to) that service rate and the optimal value of that service rate can be either maximum or minimum (we call it Max-Min optimality); When the second-order derivative of the cost function w.r.t. a particular service rate is always positive (negative), which makes the cost function strictly convex (concave), the optimal value of such service rate for the performance maximization (minimization) problem can be either maximum or minimum. To the best of our knowledge, this is the most general result for the optimality of service rates in closed Jackson networks and all the previous works only involve the first conclusion. Moreover, our result is also valid for both the state-dependent and load-dependent service rates, under both the time-average and customer-average performance criteria.

  6. Oral gugulipid in acne vulgaris management

    Directory of Open Access Journals (Sweden)

    Jaideep Dogra

    1990-01-01

    Full Text Available Gugulipid is the standardized extract of the oleo-resin of Commiphora mukul (Burseraceace an Indian medicinal plant. The active ingredients are two guggulsterones Z and E. Gugulipid is an effective hypolipidemic agent, has a marked antilipolytic activity in rats. Considering the pathogenesis of acne vulgaris and the pharmacological properties of Gugulipid this trial was initiated. Thirty patients with moderate to severe acne ( Grade 4 were included in this study. Tab Guglip was prescribed in tds dosage for 6 weeks. Excellent, good and moderate response was seen in nine (30% fourteen (46.66% and seven (23.33% patients respectively out of the total thirty. No topical treatment was recommended except for local skin -hygiene. The drug showed excellent tolerance. Only three patients (10% reported relapse when examined at 3 months follow up.

  7. Adapalene In The Treatment Of Acne Vulgaris

    Directory of Open Access Journals (Sweden)

    Prasad H R Y

    2004-01-01

    Full Text Available Topical tretinoin, a retinoid long in use for the treatment of acne vulgaris, has the disadvantage of skin irritation. Adapalene, a third generation retinoid, has been claimed to have less side-effects. We evaluated the safety and efficacy of adapalene in an open uncontrolled trial. Thirty three patients of mild to moderate acne vulgaris were included in the study. Of them, 22 patients completed the study period of 12 weeks. The mean age of all 33 patients was 19 year with male to female ratio of 1.75:1. There was significant decrease in lesion count in each of 1,4,8 and 12 weeks evaluations (p <0.05 in both inflammatory and non-inflammatory lesions. About 70% complained of burning, 60% of itching and 30% of dryness. However, none of the side-effects was severe enough to stop the medication except in one case.

  8. Enzyme production and antibiotic susceptibility of propionibacterium acnes and p. Granulosum from acne vulgaris patients and healthy persons

    OpenAIRE

    Al Hadithi, H. T. [هـ. ت. الحديثي; Khudaier, B. Y.

    1996-01-01

    Seventeen strains of Propionibacterium acnes and ten strains of P. granulosum were isolated from acne patients, in addition to ten isolates of each species from healthy persons. All strains were examined for their enzymatic activity and antibiotic susceptibility to ten antibiotics. Percentage of lipase, lecithinase and casenase production by strains of both species from acne lesions was higher than that from healthy persons in contrast to gelatinase. Haemolysin was produced almost by all stra...

  9. Should public libraries be networked with the parent service or not

    Directory of Open Access Journals (Sweden)

    Silva Novljan

    1999-01-01

    Full Text Available The National and University Library performs the role of the parent service for all types of libraries, that is also for public libraries. According to the Act on Librarianship, public libraries perform some tasks of the parent service on the horizontal level for alllibraries in a certain area. The analysis of the performance of public libraries in the last decade, carried out at the national parent service shows that the majority of advisory work was aimed at better working conditions in public libraries which are, by themselves, the platform enabling the performance of parent tasks. The analysis reveals that in the last decade, the primary aim of public libraries was their own functioning and development of their network, and to a much lesser extent concem for other libraries in their respective areas.Social changes also endangered the organization of libraries in a network, and it was not always the founders who initiated changes, doubt and despair showed up also in the libraries themselves. On the other hand, quick social changes, development of technology, diminished interest in reading and endeavours for free information access advocate networking of libaries and the maintenance of that network by parent service. The existent endeavours of the parent service for the development of libraries can serve for the reassessmentof the preservation and reinforcementoflinks among libraries in a network following modemized organization. The formation of an advisory body of representatives of public libraries should reinforce the power of advisory service for public libraries in its endeavours for better working conditions and professiona1ization of their performance.

  10. Evaluation of abrasives in acne therapy.

    Science.gov (United States)

    Mills, O H; Kligman, A M

    1979-05-01

    Various abrasive materials, such as pumice, polyethylene, and aluminum oxide are widely used as adjuncts in the therapy of acne. The apparent rationale is that abrasion should unseat comedones and deter their formation. We assessed the efficacy of various abrasives and abradant pads. Varying degrees of peeling and erythema were produced, but there was no appreciable reduction of comedones. Aggravation was noted in some cases. Generally, the resorption of papules and pustules was enhanced.

  11. POTENSI KEFIR SEBAGAI ANTIBAKTERI Propionibacterium acnes

    OpenAIRE

    Michael

    2015-01-01

    Jerawat merupakan suatu keadaan dimana pori-pori kulit tersumbat oleh kotoran dan adanya bakteri Propionibacterium acnes yang berkembang biak di daerah sumbatan tersebut. Di Indonesia, masyarakat mulai melirik suatu produk minuman yang dipercaya secara empiris dapat mengatasi masalah jerawat, yaitu produk minuman fermentasi kefir. Kefir merupakan produk fermentasi yang memiliki cita rasa asam dan sedikit beralkohol. Kefir dapat difermentasi dengan air maupun dengan susu. Kan...

  12. Reduced expression of dermcidin, a peptide active against propionibacterium acnes, in sweat of patients with acne vulgaris.

    Science.gov (United States)

    Nakano, Toshiaki; Yoshino, Takashi; Fujimura, Takao; Arai, Satoru; Mukuno, Akira; Sato, Naoya; Katsuoka, Kensei

    2015-09-01

    Dermcidin (DCD), an antimicrobial peptide with a broad spectrum of activity against bacteria such as Propionibacterum acnes, is expressed constitutively in sweat in the absence of stimulation due to injury or inflammation. The aim of this study was to determine the relationship between DCD expression and acne vulgaris associated with P. acnes. The antimicrobial activity of recombinant full-length DCD (50 μg/ml) was 97% against Escherichia coli and 100% against Staphylococcus aureus. Antimicrobial activity against P. acnes ranged from 68% at 50 μg/ml DCD to 83% at 270 μg/ml DCD. DCD concentration in sweat from patients with acne vulgaris (median 9.8 μg/ml, range 6.9-95.3 μg/ml) was significantly lower than in healthy subjects (median 136.7 μg/ml, range 45.4-201.6 μg/ml) (p = 0.001). DCD demonstrated concentration-dependent, but partial, microbicidal activity against P. acnes. These results suggest that reduced DCD concentration in sweat in patients with inflammatory acne may permit proliferation of P. acnes in pilosebaceous units, resulting in progression of inflammatory acne.

  13. Short contact therapy of acne with tretinoin.

    Science.gov (United States)

    Veraldi, Stefano; Barbareschi, Mauro; Benardon, Susanna; Schianchi, Rossana

    2013-10-01

    The most frequent side effect of topical retinoids is irritant contact dermatitis. It occurs in approximately 85% of patients; the percentage can reach up to 95% in patients treated with tretinoin. Severity of this dermatitis is moderate to severe in approximately 20% of patients. However, 15% of patients stop the treatment with tretinoin because of skin irritation. The authors used tretinoin as short contact therapy (SCT) in mild to moderate acne, in order to try to reduce the incidence and severity of irritant contact dermatitis. They present the final results of a sponsor-free, pilot, open, multicenter study. Seventy-four patients were treated with 0.05% tretinoin cream. It was applied once daily for 30 min. Treatment duration ranged from 8 to 32 weeks (mean duration: 12 weeks). Acne severity and treatment efficacy were evaluated by means of the Global Acne Grading System. A significant clinical improvement (≥50% from baseline) was observed in 41 patients (55.4%). Thirteen patients (17.6%) developed a mild skin irritation. Four patients (5.4%) stopped the treatment because of severe skin irritation. Efficacy of tretinoin used as SCT seems to be superimposable to that of tretinoin used according to standard modality. Tolerability of SCT with tretinoin is very good. This tolerability allows a high adherence of patients to the treatment and it markedly improves compliance.

  14. Aelite: A Flit-Synchronous Network on Chip with Composable and Predictable Services.

    NARCIS (Netherlands)

    Hansson, A.; Subburaman, Mahesh; Goossens, Kees

    To accommodate the growing number of applications integrated on a single chip, Networks on Chip (NoC) must offer scalability not only on the architectural, but also on the physical and functional level. In addition, real-time applications require Guaranteed Services (GS), with latency and throughput

  15. A Peer-Tree Based Location Lookup Service in Mobile Wireless Networks

    Directory of Open Access Journals (Sweden)

    Jun Liu

    2010-01-01

    Full Text Available We present a location look-up service for aiding location-based routing in wireless networks with mobile hosts. This location look up service is constructed based on a peer-tree indexing structure which represents the friendship relations among mobile hosts. The friendship is derived from the relations of sharing various-length common suffixes of host identifiers. A friendship relation determines the cooperation relation among mobile hosts. The Peer-Tree indexing structure provides a guideline for propagating location updates and queries in an organized manner. Each host periodically propagates its up-to-date location to a small number of its friends. Location queries are forwarded to and serviced at one of the hosts which hold a copy of the location under query. Paths for forwarding location updates or queries are jointly determined by the Peer-Tree indexing structure and the temporary connectivity in a network. The goals of this location look-up service include achieving a high success rate on location discovery, having low demands on network resources, and being robust to frequent changes of network topology.

  16. Building the Bridge between Operations and Outcomes : Modelling and Evaluation of Health Service Provider Networks

    NARCIS (Netherlands)

    M. Mahdavi (Mahdi)

    2015-01-01

    markdownabstract__Abstract__ The PhD research has two objectives: - To develop generally applicable operational models which allow developing the evidence base for health service operations in provider networks. - To contribute to the evidence base by validating the model through

  17. Data Archiving and Networked Services (DANS) promotes sustained access to digital research data

    NARCIS (Netherlands)

    van Berchum, M.; Kraaikamp, Emilie

    2015-01-01

    Data Archiving and Networked Services (DANS) promotes sustained access to digital research data. For this purpose, DANS encourages researchers to archive and reuse data in a sustained form. In the online archiving system EASY research data is stored in a permanent and sustainable manner, according

  18. Understanding Opportunistic Networking for Emergency Services: Analysis of One Year of GPS Traces

    NARCIS (Netherlands)

    S. Cabrero Barros (Sergio); R. García; X.G. Pañeda; D. Melendi

    2015-01-01

    htmlabstractOpportunistic networking can help emergency services in both their daily operation and disaster relief. This idea has been extensively explored in previous research, but most studies are based on little knowledge of real mobility. In order to support future research, this paper analyses

  19. Resource-based interdependencies in value networks for mobile Internet services

    NARCIS (Netherlands)

    Montalvo, U.W. de; Kar, E. van de; Maitland, C.

    2004-01-01

    The advent of new electronic platforms, such as fixed and mobile Internet, is forcing firms from a range of industries to come together in so-called 'value networks' for the provision of innovative services. Firms from different industries have widely varying resources. Our analysis is aimed at

  20. Social network as a determinant of pathway to mental health service ...

    African Journals Online (AJOL)

    The presence of some social network and social support structures were significantly associated with the use of general medical and specialty psychiatric services for patients with schizophrenia (P = 0.03), schizoaffective disorder (P = 0.02), bipolar I disorder (P = 0.01), but not with major depression and symptoms of ...

  1. TownshipNet: A localized hybrid TVWS-WiFi and cloud services network

    CSIR Research Space (South Africa)

    Hadzic, S

    2016-10-01

    Full Text Available This paper describes a network architecture to provide low cost last mile access and cloud services for local content sharing in a poorly resourced township environment. We describe how ICT solutions are developed in close partnership with the local...

  2. Evolutionary optimization for energy efficient service provisioning in IT and optical network infrastructures.

    Science.gov (United States)

    Anastasopoulos, Markos P; Tzanakaki, Anna; Georgakilas, Konstantinos

    2011-12-12

    This paper focuses on energy efficient service provisioning in integrated IT and optical network infrastructures. A novel evolutionary distributed approach is proposed and compared with ILP based centralized approaches and modeling results quantify similar performance. © 2011 Optical Society of America

  3. Performance Evaluation of a Cluster-Based Service Discovery Protocol for Heterogeneous Wireless Sensor Networks

    NARCIS (Netherlands)

    Marin Perianu, Raluca; Scholten, Johan; Havinga, Paul J.M.; Hartel, Pieter H.

    2006-01-01

    Abstract—This paper evaluates the performance in terms of resource consumption of a service discovery protocol proposed for heterogeneous Wireless Sensor Networks (WSNs). The protocol is based on a clustering structure, which facilitates the construction of a distributed directory. Nodes with higher

  4. 78 FR 14359 - Verizon Business Networks Services, Inc., Senior Analysts-Order Management, Voice Over Internet...

    Science.gov (United States)

    2013-03-05

    ... Management, Voice Over Internet Protocol, Small And Medium Business, Tampa, Florida; Verizon Business Networks Services, Inc., Senior Coordinator-Order Management, Voice Over Internet Protocol, Small And... Analysts-Order Management, Voice Over Internet Protocol, Small and Medium Business, Tampa, Florida. The...

  5. Children in Protective Services: The Missing Educational Link for Children in Kinship Networks.

    Science.gov (United States)

    Rittner, Barbara; Sacks, Arlene

    1995-01-01

    Explores how school social workers and children's protective services (CPS) can collaborate to improve the social and educational functioning of maltreated children living in kinship networks. A collaboration model between school social workers and CPS is suggested using provisions of the Individuals with Disabilities Act. (JPS)

  6. Efficient Bandwidth Allocation for Integrated Services in Broadband Wireless ATM Networks

    DEFF Research Database (Denmark)

    Liu, Hong; Dittmann, Lars; Gliese, Ulrik Bo

    1999-01-01

    An efficient bandwidth allocation scheme is proposed for supporting intergrated services in wireless ATM networks. These include CBR, VBR amd ABR types of traffic. The proposed scheme is based om A-PRMA for carrying ATM traffic in a dynamic TDMA type access system. It allows mobile users to adjust...

  7. Prototype of a Mobile Social Network for Education Using Dynamic Web Service

    Science.gov (United States)

    Hoentsch, Sandra Costa Pinto; Carvalho, Felipe Oliveira; Santos, Luiz Marcus Monteiro de Almeida; Ribeiro, Admilson de Ribamar Lima

    2012-01-01

    This article presents the proposal of a social network site SocialNetLab that belongs to the Department of Computing-Federal University of Sergipe and which aims to locate and notify users of a nearby friend independently of the location technology available in the equipment through dynamic Web Service; to serve as a laboratory for research in…

  8. Predictors of College Students' Willingness to Use Social Network Services: The Case of Two Turkish Universities

    Science.gov (United States)

    Çelik, Ali Kemal; Karaaslan, Abdulkerim

    2014-01-01

    Purpose: The purpose of this paper is to determine predictors of social network services use among college students at two Turkish universities, with particular emphasis on Facebook, Twitter, Foursquare, and Instagram. Design/methodology/approach: A written questionnaire was administered to 822 college students from various faculties. The data…

  9. A Social Learning Management System Supporting Feedback for Incorrect Answers Based on Social Network Services

    Science.gov (United States)

    Son, Jiseong; Kim, Jeong-Dong; Na, Hong-Seok; Baik, Doo-Kwon

    2016-01-01

    In this research, we propose a Social Learning Management System (SLMS) enabling real-time and reliable feedback for incorrect answers by learners using a social network service (SNS). The proposed system increases the accuracy of learners' assessment results by using a confidence scale and a variety of social feedback that is created and shared…

  10. Quantified Academic Selves: The Gamification of Research through Social Networking Services

    Science.gov (United States)

    Hammarfelt, Björn; de Rijcke, Sarah; Rushforth, Alexander D.

    2016-01-01

    Introduction: Our study critically engages with techniques of self-quantification in contemporary academia, by demonstrating how social networking services enact research and scholarly communication as a "game". Method: The empirical part of the study involves an analysis of two leading platforms: Impactstory and ResearchGate. Observed…

  11. Integrated Information and Network Management for End-to-End Quality of Service

    Science.gov (United States)

    2011-11-01

    Integrated Information and Network Management for End-to-End Quality of Service Marco Carvalho and Adrian Granados Florida Institute for...Carvalho, M., Granados A., Naqwi, W., Brothers, A., Hanna, J., and Turck, K., “A cross-layer communications substrate for tactical information management

  12. Cooperative Power Saving Strategies for IP-Services Supported over DVB-H Networks

    DEFF Research Database (Denmark)

    Zhang, Qi; Fitzek, F.H.P.; Katz, Marcos

    2007-01-01

    This paper introduces power saving strategies for cooperative wireless communication systems. The described scenario focuses on IP-services over DVB-H networks showing the strength of non-altruistic cooperation between mobile devices. The envisioned cooperation is based on cellular reception...

  13. Quantified academic selves : The gamification of science through social networking services

    NARCIS (Netherlands)

    Hammarfelt, B.M.S.; Rijcke, de S.; Rushforth, A.D.

    2016-01-01

    Introduction. Our study critically engages with techniques of self-quantification in contemporary academia, by demonstrating how social networking services enact research and scholarly communication as a 'game'. Method. The empirical part of the study involves an analysis of two leading platforms:

  14. Allocating service parts in two-echelon networks at a utility company

    NARCIS (Netherlands)

    van den Berg, D.; van der Heijden, Matthijs C.; Schuur, Peter

    2016-01-01

    We study a multi-item, two-echelon, continuous-review inventory problem at a Dutch utility company. We develop a model for the optimal allocation of service parts in a two-echelon network under an aggregate waiting time constraint. Specific model aspects are emergency shipments in case of stockout,

  15. Marketing of Academic Library Services through Social Networking Sites: Implications of Electronic Word-of-Mouth

    Science.gov (United States)

    Siddike, Md. Abul Kalam; Kiran, K.

    2015-01-01

    The main objective of this study is to investigate the perceptions of academic librarians towards the marketing of library services through social networking sites (SNSs) and their understanding of using electronic word-of-mouth (eWOM) as a marketing tool in academic libraries. This study follows a qualitative data-gathering approach of structured…

  16. Professional Networks among Rural School Food Service Directors Implementing the Healthy, Hunger-Free Kids Act

    Science.gov (United States)

    Lubker Cornish, Disa; Askelson, Natoshia M.; Golembiewski, Elizabeth H.

    2015-01-01

    Purpose/Objectives: This study was designed to explore the professional networks of rural school food service directors (FSD), the resources they use for implementing the Healthy, Hunger-free Kids Act of 2010 (HHFKA), and their needs for information and support to continue to implement successfully. Methods: Rural FSD participated in an in-depth…

  17. Utilizing Social Network Services for Enhanced Communication with Elderly Living at Home

    DEFF Research Database (Denmark)

    Wagner, Stefan

    2009-01-01

    This paper discusses whether social network services, like Facebook and Twitter, may be used by elderly living in their own homes to enhance communication with their relatives and friends. It introduces a prototype solution based on the iRobot Roomba 560, iRobot, USA, robot vacuum cleaner, which...

  18. Acné: un nuevo aporte terapéutico Acne: a new therapeutical approach

    OpenAIRE

    C. M. M. Paiva

    2007-01-01

    El acné es una patología que afecta casi al 80% de la población en algún momento de la vida. Múltiples terapéuticas locales y generales han sido utilizadas. En el presente estudio evaluamos la eficacia y seguridad del tratamiento de las lesiones activas de acné con luz pulsada como única terapéutica. Fueron tratados 91 pacientes y los resultados indican que la fototerapia es una opción terapéutica local con pocos efectos colaterales que evitaría el uso de drogas por vía general. Estos resulta...

  19. A Secure and Stable Multicast Overlay Network with Load Balancing for Scalable IPTV Services

    Directory of Open Access Journals (Sweden)

    Tsao-Ta Wei

    2012-01-01

    Full Text Available The emerging multimedia Internet application IPTV over P2P network preserves significant advantages in scalability. IPTV media content delivered in P2P networks over public Internet still preserves the issues of privacy and intellectual property rights. In this paper, we use SIP protocol to construct a secure application-layer multicast overlay network for IPTV, called SIPTVMON. SIPTVMON can secure all the IPTV media delivery paths against eavesdroppers via elliptic-curve Diffie-Hellman (ECDH key exchange on SIP signaling and AES encryption. Its load-balancing overlay tree is also optimized from peer heterogeneity and churn of peer joining and leaving to minimize both service degradation and latency. The performance results from large-scale simulations and experiments on different optimization criteria demonstrate SIPTVMON's cost effectiveness in quality of privacy protection, stability from user churn, and good perceptual quality of objective PSNR values for scalable IPTV services over Internet.

  20. Interprofessional practice and learning in a youth mental health service: A case study using network analysis.

    Science.gov (United States)

    Barnett, Tony; Hoang, Ha; Cross, Merylin; Bridgman, Heather

    2015-01-01

    Few studies have examined interprofessional practice (IPP) from a mental health service perspective. This study applied a mixed-method approach to examine the IPP and learning occurring in a youth mental health service in Tasmania, Australia. The aims of the study were to investigate the extent to which staff were networked, how collaboratively they practiced and supported student learning, and to elicit the organisation's strengths and opportunities regarding IPP and learning. Six data sets were collected: pre- and post-test readiness for interprofessional learning surveys, Social Network survey, organisational readiness for IPP and learning checklist, "talking wall" role clarification activity, and observations of participants working through a clinical case study. Participants (n = 19) were well-networked and demonstrated a patient-centred approach. Results confirmed participants' positive attitudes to IPP and learning and identified ways to strengthen the organisation's interprofessional capability. This mixed-method approach could assist others to investigate IPP and learning.