WorldWideScience

Sample records for net balance expressed

  1. Positive muscle protein net balance and differential regulation of atrogene expression after resistance exercise and milk protein supplementation

    DEFF Research Database (Denmark)

    Reitelseder, Søren; Agergaard, Jakob; Doessing, Simon

    2014-01-01

    Purpose Resistance exercise and amino acid availability are positive regulators of muscle protein net balance (NB). However, anabolic responses to resistance exercise and protein supplementation deserve further elucidation. The purpose was to compare intakes of whey, caseinate (both: 0.30 g/kg lean...... body mass), or a non-caloric control after heavy resistance exercise on protein turnover and mRNA expressions of forkhead homeobox type O (FOXO) isoforms, muscle RING finger 1 (MuRF1), and Atrogin1 in young healthy males. Methods Protein turnover was determined by stable isotope-labeled leucine...

  2. Net energy balance of tokamak fusion power plants

    International Nuclear Information System (INIS)

    Buende, R.

    1981-10-01

    The net energy balance for a tokamak fusion power plant was determined by using a PWR power plant as reference system, replacing the fission-specific components by fusion-specific components and adjusting the non-reactor-specific components to altered conditions. For determining the energy input to the fusion plant a method was developed that combines the advantages of the energetic input-output method with those of process chain analysis. A comparison with PWR, HTR, FBR, and coal-fired power plants is made. As a result the net energy balance of the fusion power plant turns out to be more advantageous than that of an LWR, HTR or coal-fired power plant and nearly in the same range as FBR power plants. (orig.)

  3. 47 CFR 69.608 - Carrier Common Line hypothetical net balance.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Carrier Common Line hypothetical net balance. 69.608 Section 69.608 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER... net balance. The hypothetical net balance shall be equal to a Carrier Common Line revenue requirement...

  4. Net energy balance of tokamak fusion power plants

    International Nuclear Information System (INIS)

    Buende, R.

    1983-01-01

    The net energy balance for a tokamak fusion power plant of present day design is determined by using a PWR power plant as reference system, replacing the fission-specific components by fusion-specific components and adjusting the non-reactor-specific components to altered conditions. For determining the energy input to the fusion plant a method was developed that combines the advantages of the energetic input-output method with those of process chain analysis. A comparison with PWR, HTR, FBR, and coal-fired power plants is made. As a result the energy expenditures of the fusion power plant turn out to be lower than that of an LWR, HTR, or coal-fired power plant of equal net electric power output and nearly in the same range as FBR power plants. (orig.)

  5. Organic carbon balance and net ecosystem metabolism in Chesapeake Bay

    Science.gov (United States)

    Kemp, W.M.; Smith, E.M.; Marvin-DiPasquale, M.; Boynton, W.R.

    1997-01-01

    The major fluxes of organic carbon associated with physical transport and biological metabolism were compiled, analyzed and compared for the mainstem portion of Chesapeake Bay (USA). In addition, 5 independent methods were used to calculate the annual mean net ecosystem metabolism (NEM = production - respiration) for the integrated Bay. These methods, which employed biogeochemical models, nutrient mass-balances anti summation of individual organic carbon fluxes, yielded remarkably similar estimates, with a mean NEM of +50 g C m-2 yr-1 (?? SE = 751, which is approximately 8% of the estimated annual average gross primary production. These calculations suggest a strong cross-sectional pattern in NEM throughout the Bay, wherein net heterotrophic metabolism prevails in the pelagic zones of the main channel, while net autotrophy occurs in the littoral zones which flank the deeper central area. For computational purposes, the estuary was separated into 3 regions along the land-sea gradient: (1) the oligohaline Upper Bay (11% of total area); (2) the mesohaline Mid Bay (36% of area); and (3) the polyhaline Lower Bay (53% of area). A distinct regional trend in NEM was observed along this salinity gradient, with net here(atrophy (NEM = 87 g C m-2 yr-1) in the Upper Bay, balanced metabolism in the Mid Bay and net autotrophy (NEM = +92 g C m-2 yr-1) in the Lower Bay. As a consequence of overall net autotrophy, the ratio of dissolved inorganic nitrogen (DIN) to total organic nitrogen (TON) changed from DIN:TON = 5.1 for riverine inputs to DIN:TON = 0.04 for water exported to the ocean. A striking feature of this organic C mass-balance was the relative dominance of biologically mediated metabolic fluxes compared to physical transport fluxes. The overall ratio of physical TOC inputs (1) to biotic primary production (P) was 0.08 for the whole estuary, but varied dramatically from 2.3 in the Upper Bay to 0.03 in the Mid and Lower Bay regions. Similarly, ecosystem respiration was

  6. Energy balance framework for Net Zero Energy buildings

    Science.gov (United States)

    Approaching a Net Zero Energy (NZE) building goal based on current definitions is flawed for two principal reasons - they only deal with energy quantities required for operations, and they do not establish a threshold, which ensures that buildings are optimized for reduced consum...

  7. Dissolved carbon leaching from soil is a crucial component of the net ecosystem carbon balance

    DEFF Research Database (Denmark)

    Kindler, Reimo; Siemens, Jan; Kaiser, Klaus

    2011-01-01

    ecosystem exchange (NEE) plus carbon inputs with fertilization minus carbon removal with harvest. Carbon leaching increased the net losses from cropland soils by 24–105% (median: 25%). For the majority of forest sites, leaching hardly affected actual net ecosystem carbon balances because of the small...... solubility of CO2 in acidic forest soil solutions and large NEE. Leaching of CH4 proved to be insignificant compared with other fluxes of carbon. Overall, our results show that leaching losses are particularly important for the carbon balance of agricultural systems....

  8. Energy balance of maize production in Brazil: the energetic constraints of a net positive outcome

    Energy Technology Data Exchange (ETDEWEB)

    Soares, Luis Henrique de Barros; Alves, Bruno Jose Rodrigues; Urquiaga, Segundo

    2008-07-01

    Among the factors used to analyze and to establish the sustainability of a whole agricultural production system, the energy balance is one of the most powerful and robust. The maize production in Brazil is surely the reflex of an energy intensive system that demands many field operations and heavy fertilizer applications, notably nitrogen in urea form. This work presents an energy balance of this major crop adjusted to the Brazilian conditions of cultivation. The input components were grouped based on their energy contents, and the possible improvements in the agricultural practices that could improve energy balance and net energy withdrawn from the farming were considered. The replacement of N synthetic fertilizer by biological nitrogen fixation, whether the process is directly carried out by endophytic diazotroph bacteria or by means of a N{sub 2}- fixing legume culture planted before the main crop as a green-manure is also discussed. (author)

  9. Multi-year net ecosystem carbon balance at a horticulture-extracted restored peatland

    Science.gov (United States)

    Nugent, Kelly; Strachan, Ian; Strack, Maria

    2017-04-01

    small source of CO2, NEE in the Typha plots showed significantly greater CO2 uptake capacity relative to any other restored plant community. High productivity combined with reduced CH4 flux suggests that Typha may be playing a key role in reducing the overall impact of the remnant ditches on the net ecosystem carbon balance. A preliminary footprint analysis suggests that ecosystem-level CH4 flux is being primarily driven by release from hotspots while the majority of the tower source area is a very small source of methane.

  10. 16 CFR 500.7 - Net quantity of contents, method of expression.

    Science.gov (United States)

    2010-01-01

    ... expression. The net quantity of contents shall be expressed in terms of weight or mass, measure, numerical... consumers. The net quantity of contents statement shall be in terms of fluid measure if the commodity is liquid, or in terms of weight or mass if the commodity is solid, semi-solid, or viscous, or a mixture of...

  11. Net energy balance of molasses based ethanol. The case of Nepal

    International Nuclear Information System (INIS)

    Khatiwada, Dilip; Silveira, Semida

    2009-01-01

    This paper evaluates life cycle energy analysis of molasses based ethanol (MOE) in Nepal. Net energy value (NEV), net renewable energy value (NREV) and energy yield ratio are used to evaluate the energy balance of MOE in Nepal. Total energy requirements in sugarcane farming, cane milling and ethanol conversion processes are estimated and energy allocation is made between co-products (molasses and sugar) as per their market prices. The result shows negative NEV (-13.05 MJ/L), positive NREV (18.36 MJ/L) and energy yield ratio (7.47). The higher positive value of NREV and energy yield ratio reveal that a low amount of fossil fuels are required to produce 1 L of MOE. However, negative NEV reveals that the total energy consumption (both fossil and renewables) to produce the ethanol is higher than its final energy content. Nevertheless, the renewable energy contribution amounts to 91.7% of total energy requirements. The effect of the increased price of molasses and reduced energy consumption in the sugarcane milling and ethanol conversion are found to be significant in determining the energy values and yield ratio of MOE. In addition, there are clear measures that can be taken to improve efficiency along the production chain. Finally, energy security, scarcity of hard currency for importing fossil fuels and opportunities for regional development are also strong reasons for considering local renewable energy options in developing countries. (author)

  12. Controls on declining carbon balance with leaf age among 10 woody species in Australian woodland: do leaves have zero daily net carbon balances when they die?

    Science.gov (United States)

    Reich, Peter B; Falster, Daniel S; Ellsworth, David S; Wright, Ian J; Westoby, Mark; Oleksyn, Jacek; Lee, Tali D

    2009-01-01

    * Here, we evaluated how increased shading and declining net photosynthetic capacity regulate the decline in net carbon balance with increasing leaf age for 10 Australian woodland species. We also asked whether leaves at the age of their mean life-span have carbon balances that are positive, zero or negative. * The net carbon balances of 2307 leaves on 53 branches of the 10 species were estimated. We assessed three-dimensional architecture, canopy openness, photosynthetic light response functions and dark respiration rate across leaf age sequences on all branches. We used YPLANT to estimate light interception and to model carbon balance along the leaf age sequences. * As leaf age increased to the mean life-span, increasing shading and declining photosynthetic capacity each separately reduced daytime carbon gain by approximately 39% on average across species. Together, they reduced daytime carbon gain by 64% on average across species. * At the age of their mean life-span, almost all leaves had positive daytime carbon balances. These per leaf carbon surpluses were of a similar magnitude to the estimated whole-plant respiratory costs per leaf. Thus, the results suggest that a whole-plant economic framework, including respiratory costs, may be useful in assessing controls on leaf longevity.

  13. Posters: balancing overkill and freedom of expression

    CERN Multimedia

    CERN Internal Communication and HR Department

    2014-01-01

    The number of posters put up at CERN to inform, engage and invite is growing quickly, and they are taking over an ever-increasing number of walls, doors, pillars and glass panels. In the interests of freedom of information, no official restrictions are in place, but we are nonetheless obliged to maintain a fair balance. Here we discuss this issue.   Posters clamour for our attention, becoming more and more invasive and often eternal as they are never taken down... While the need to inform and to be informed is a legitimate one, we also have to respect our workplace. It’s no surprise that walls or pillars (sometimes freshly painted) at junctions in corridors that are busy at peak times are seen as ideal targets by people who want to publicise their events or activities, but this abundance, or overabundance, of posters is sometimes seen as vandalism of communal areas. What's more, the posters themselves are sometimes vandalised: comments, sometimes offensive, may be added and the...

  14. The impacts of tropical cyclones on the net carbon balance of eastern US forests (1851-2000)

    Science.gov (United States)

    Fisk, J. P.; Hurtt, G. C.; Chambers, J. Q.; Zeng, H.; Dolan, K. A.; Negrón-Juárez, R. I.

    2013-12-01

    In temperate forests of the eastern US, tropical cyclones are a principal agent of catastrophic wind damage, with dramatic impacts on the structure and functioning of forests. Substantial progress has been made to quantify forest damage and resulting gross carbon emissions from tropical cyclones. However, the net effect of storms on the carbon balance of forests depends not only on the biomass lost in single events, but also on the uptake during recovery from a mosaic of past events. This study estimates the net impacts of tropical cyclones on the carbon balance of US forests over the period 1851-2000. To track both disturbance and recovery and to isolate the effects of storms, a modeling framework is used combining gridded historical estimates of mortality and damage with a mechanistic model using an ensemble approach. The net effect of tropical cyclones on the carbon balance is shown to depend strongly on the spatial and temporal scales of analysis. On average, tropical cyclones contribute a net carbon source over latter half of the 19th century. However, throughout much of the 20th century a regional carbon sink is estimated resulting from periods of forest recovery exceeding damage. The large-scale net annual flux resulting from tropical cyclones varies by up to 50 Tg C yr-1, an amount equivalent to 17%-36% of the US forest carbon sink.

  15. The impacts of tropical cyclones on the net carbon balance of eastern US forests (1851–2000)

    International Nuclear Information System (INIS)

    Fisk, J P; Hurtt, G C; Dolan, K A; Chambers, J Q; Zeng, H; Negrón-Juárez, R I

    2013-01-01

    In temperate forests of the eastern US, tropical cyclones are a principal agent of catastrophic wind damage, with dramatic impacts on the structure and functioning of forests. Substantial progress has been made to quantify forest damage and resulting gross carbon emissions from tropical cyclones. However, the net effect of storms on the carbon balance of forests depends not only on the biomass lost in single events, but also on the uptake during recovery from a mosaic of past events. This study estimates the net impacts of tropical cyclones on the carbon balance of US forests over the period 1851–2000. To track both disturbance and recovery and to isolate the effects of storms, a modeling framework is used combining gridded historical estimates of mortality and damage with a mechanistic model using an ensemble approach. The net effect of tropical cyclones on the carbon balance is shown to depend strongly on the spatial and temporal scales of analysis. On average, tropical cyclones contribute a net carbon source over latter half of the 19th century. However, throughout much of the 20th century a regional carbon sink is estimated resulting from periods of forest recovery exceeding damage. The large-scale net annual flux resulting from tropical cyclones varies by up to 50 Tg C yr −1 , an amount equivalent to 17%–36% of the US forest carbon sink. (letter)

  16. Estimation of net greenhouse gas balance using crop- and soil-based approaches: Two case studies

    International Nuclear Information System (INIS)

    Huang, Jianxiong; Chen, Yuanquan; Sui, Peng; Gao, Wansheng

    2013-01-01

    The net greenhouse gas balance (NGHGB), estimated by combining direct and indirect greenhouse gas (GHG) emissions, can reveal whether an agricultural system is a sink or source of GHGs. Currently, two types of methods, referred to here as crop-based and soil-based approaches, are widely used to estimate the NGHGB of agricultural systems on annual and seasonal crop timescales. However, the two approaches may produce contradictory results, and few studies have tested which approach is more reliable. In this study, we examined the two approaches using experimental data from an intercropping trial with straw removal and a tillage trial with straw return. The results of the two approaches provided different views of the two trials. In the intercropping trial, NGHGB estimated by the crop-based approach indicated that monocultured maize (M) was a source of GHGs (− 1315 kg CO 2 −eq ha −1 ), whereas maize–soybean intercropping (MS) was a sink (107 kg CO 2 −eq ha −1 ). When estimated by the soil-based approach, both cropping systems were sources (− 3410 for M and − 2638 kg CO 2 −eq ha −1 for MS). In the tillage trial, mouldboard ploughing (MP) and rotary tillage (RT) mitigated GHG emissions by 22,451 and 21,500 kg CO 2 −eq ha −1 , respectively, as estimated by the crop-based approach. However, by the soil-based approach, both tillage methods were sources of GHGs: − 3533 for MP and − 2241 kg CO 2 −eq ha −1 for RT. The crop-based approach calculates a GHG sink on the basis of the returned crop biomass (and other organic matter input) and estimates considerably more GHG mitigation potential than that calculated from the variations in soil organic carbon storage by the soil-based approach. These results indicate that the crop-based approach estimates higher GHG mitigation benefits compared to the soil-based approach and may overestimate the potential of GHG mitigation in agricultural systems. - Highlights: • Net greenhouse gas balance (NGHGB) of

  17. A NetCDF version of the two-dimensional energy balance model based on the full multigrid algorithm

    Science.gov (United States)

    Zhuang, Kelin; North, Gerald R.; Stevens, Mark J.

    A NetCDF version of the two-dimensional energy balance model based on the full multigrid method in Fortran is introduced for both pedagogical and research purposes. Based on the land-sea-ice distribution, orbital elements, greenhouse gases concentration, and albedo, the code calculates the global seasonal surface temperature. A step-by-step guide with examples is provided for practice.

  18. Net community production and metabolic balance at the oligotrophic ocean site, station ALOHA

    Science.gov (United States)

    le B. Williams, Peter J.; Morris, Paul J.; Karl, David M.

    2004-11-01

    To test the hypothesis that in oligotrophic areas of the ocean respiration exceeds production, a 12-month study was undertaken of in vitro-determined net oxygen production and consumption in the top 150 m of the water column at the extreme oligotrophic site, Station ALOHA, in the North Pacific subtropical gyre. Throughout the year the water column was observed to be in metabolic deficit, the calculated cumulative shortfall being 9±1.7 mol O2 m-2 a-1 (approximately 100 g C m-2 a-1), an amount equivalent to 40% of measured production (annual estimated rates of production and consumption were, respectively, 22 and 31 mol O2 m-2 a-1). We consider three possible explanations for the observed deficit: the in vitro oxygen rate measurements, in themselves, are fundamentally flawed and should be discounted, the observations are correct and the observed deficit is a true account of the balance of oxygen (and organic carbon) at Station ALOHA, or the observations are correct as they stand, but need not be interpreted as organic carbon imbalance for that ecosystem. We find no error unique to the oxygen rate measurements themselves. We find also no evidence that the associated organic carbon deficit can be sustained over the long-term by internal organic reserves or by external subsidy. Accordingly we accept the geochemical findings that calculated in situ oxygen flux requires the euphotic zone of the water column at this site to be slightly (circa 2 mol C m-2 a-1) autotrophic, in contrast to the simple analysis of our observations which gives a net heterotrophic water column. We discuss a number of processes that may give rise to the observed discrepancy. In part it may derive from the difficulty of reproducing the variations in the light field experienced by an algal cell due to vertical advection. It may also derive from the intermittency of production. This latter effect would manifest itself in the following manner. Because of its universal distribution in the food web

  19. MPIGeneNet: Parallel Calculation of Gene Co-Expression Networks on Multicore Clusters.

    Science.gov (United States)

    Gonzalez-Dominguez, Jorge; Martin, Maria J

    2017-10-10

    In this work we present MPIGeneNet, a parallel tool that applies Pearson's correlation and Random Matrix Theory to construct gene co-expression networks. It is based on the state-of-the-art sequential tool RMTGeneNet, which provides networks with high robustness and sensitivity at the expenses of relatively long runtimes for large scale input datasets. MPIGeneNet returns the same results as RMTGeneNet but improves the memory management, reduces the I/O cost, and accelerates the two most computationally demanding steps of co-expression network construction by exploiting the compute capabilities of common multicore CPU clusters. Our performance evaluation on two different systems using three typical input datasets shows that MPIGeneNet is significantly faster than RMTGeneNet. As an example, our tool is up to 175.41 times faster on a cluster with eight nodes, each one containing two 12-core Intel Haswell processors. Source code of MPIGeneNet, as well as a reference manual, are available at https://sourceforge.net/projects/mpigenenet/.

  20. Towards a sustainable global energy supply infrastructure: Net energy balance and density considerations

    International Nuclear Information System (INIS)

    Kessides, Ioannis N.; Wade, David C.

    2011-01-01

    This paper employs a framework of dynamic energy analysis to model the growth potential of alternative electricity supply infrastructures as constrained by innate physical energy balance and dynamic response limits. Coal-fired generation meets the criteria of longevity (abundance of energy source) and scalability (ability to expand to the multi-terawatt level) which are critical for a sustainable energy supply chain, but carries a very heavy carbon footprint. Renewables and nuclear power, on the other hand, meet both the longevity and environmental friendliness criteria. However, due to their substantially different energy densities and load factors, they vary in terms of their ability to deliver net excess energy and attain the scale needed for meeting the huge global energy demand. The low power density of renewable energy extraction and the intermittency of renewable flows limit their ability to achieve high rates of indigenous infrastructure growth. A significant global nuclear power deployment, on the other hand, could engender serious risks related to proliferation, safety, and waste disposal. Unlike renewable sources of energy, nuclear power is an unforgiving technology because human lapses and errors can have ecological and social impacts that are catastrophic and irreversible. Thus, the transition to a low carbon economy is likely to prove much more challenging than early optimists have claimed. - Highlights: → We model the growth potential of alternative electricity supply infrastructures. → Coal is scalable and abundant but carries a heavy carbon footprint. → Renewables and nuclear meet the longevity and environmental friendliness criteria. → The low power density and intermittency of renewables limit their growth potential. → Nuclear power continues to raise concerns about proliferation, safety, and waste.

  1. A NetCDF version of the two-dimensional energy balance model based on the full multigrid algorithm

    Directory of Open Access Journals (Sweden)

    Kelin Zhuang

    2017-01-01

    Full Text Available A NetCDF version of the two-dimensional energy balance model based on the full multigrid method in Fortran is introduced for both pedagogical and research purposes. Based on the land–sea–ice distribution, orbital elements, greenhouse gases concentration, and albedo, the code calculates the global seasonal surface temperature. A step-by-step guide with examples is provided for practice.

  2. Nets solution of flow for gases, using the Balance Pattern of Nodes and the method of linealization of equations

    International Nuclear Information System (INIS)

    Narvaez, Paulo Cesar

    1999-01-01

    The dimension of nets of distribution of gases is a complex problem, so much for the diversity of the phenomena that they are presented, like for the variation of the properties of the fluids, especially, the density for effect of the changes in the pressure along the net. This work presents a model for its simulation starting from the deduction of the general equation of flow in stable and isothermal state, its inclusion in the pattern of balance of nodes and the solution of this for the method of linealization of equations. Additionally, a summary of the empiric equations more used is made for the calculation of the fall of pressure for gases flowing in pipes and an example that it illustrates the application of the pattern and the developed method

  3. Net ecosystem exchange of CO2 and carbon balance for eight temperate organic soils under agricultural management

    DEFF Research Database (Denmark)

    Elsgaard, Lars; Görres, C.-M.; Hoffmann, Carl Christian

    2012-01-01

    This study presents the first annual estimates of net ecosystem exchange (NEE) of CO2 and net ecosystem carbon balances (NECB) of contrasting Danish agricultural peatlands. Studies were done at eight sites representing permanent grasslands (PG) and rotational (RT) arable soils cropped to barley......, potato or forage grasses in three geo-regional settings. Using an advanced flux-chamber technique, NEE was derived from modelling of ecosystem respiration (ER) and gross primary production (GPP) with temperature and photosynthetically active radiation as driving variables. At PG (n = 3) and RT (n = 5......) sites, NEE (mean ± standard error, SE) was 5.1 ± 0.9 and 8.6 ± 2.0 Mg C ha−1 yr−1, respectively, but with the overall lowest value observed for potato cropping (3.5 Mg C ha−1 yr−1). This was partly attributed to a short-duration vegetation period and drying of the soil especially in potato ridges. NECB...

  4. The NetQuakes Project - Seeking a Balance Between Science and Citizens.

    Science.gov (United States)

    Luetgert, J. H.; Oppenheimer, D. H.

    2012-12-01

    The challenge for any system that uses volunteer help to do science is to dependably acquire quality data without unduly burdening the volunteer. The NetQuakes accelerograph and its data acquisition system were created to address the recognized need for more densely sampled strong ground motion recordings in urban areas to provide more accurate ShakeMaps for post-earthquake disaster assessment and to provide data for structural engineers to improve design standards. The recorder has 18 bit resolution with ±3g internal tri-axial MEMS accelerometers. Data are continuously recorded at 200 sps into a 1-2 week ringbuffer. When triggered, a miniSEED file is sent to USGS servers via the Internet. Data can also be recovered from the ringbuffer by a remote request through the NetQuakes servers. Following a power failure, the instrument can run for 36 hours using its internal battery. We rely upon cooperative citizens to host the dataloggers, provide power and Internet connectivity and perform minor servicing. Instrument and battery replacement are simple tasks that can be performed by hosts, thus reducing maintenance costs. Communication with the instrument to acquire data or deliver firmware is accomplished by file transfers using NetQuakes servers. The client instrument initiates all client-server interactions, so it safely resides behind a host's firewall. A connection to the host's LAN, and from there to the public Internet, can be made using WiFi to minimize cabling. Although timing using a cable to an external GPS antenna is possible, it is simpler to use the Network Time Protocol (NTP) to discipline the internal clock. This approach achieves timing accuracy substantially better than a sample interval. Since 2009, we have installed more than 140 NetQuakes instruments in the San Francisco Bay Area and have successfully integrated their data into the near real time data stream of the Northern California Seismic System. An additional 235 NetQuakes instruments have been

  5. Energy balance of the global photovoltaic (PV) industry--is the PV industry a net electricity producer?

    Science.gov (United States)

    Dale, Michael; Benson, Sally M

    2013-04-02

    A combination of declining costs and policy measures motivated by greenhouse gas (GHG) emissions reduction and energy security have driven rapid growth in the global installed capacity of solar photovoltaics (PV). This paper develops a number of unique data sets, namely the following: calculation of distribution of global capacity factor for PV deployment; meta-analysis of energy consumption in PV system manufacture and deployment; and documentation of reduction in energetic costs of PV system production. These data are used as input into a new net energy analysis of the global PV industry, as opposed to device level analysis. In addition, the paper introduces a new concept: a model tracking energetic costs of manufacturing and installing PV systems, including balance of system (BOS) components. The model is used to forecast electrical energy requirements to scale up the PV industry and determine the electricity balance of the global PV industry to 2020. Results suggest that the industry was a net consumer of electricity as recently as 2010. However, there is a >50% that in 2012 the PV industry is a net electricity provider and will "pay back" the electrical energy required for its early growth before 2020. Further reducing energetic costs of PV deployment will enable more rapid growth of the PV industry. There is also great potential to increase the capacity factor of PV deployment. These conclusions have a number of implications for R&D and deployment, including the following: monitoring of the energy embodied within PV systems; designing more efficient and durable systems; and deploying PV systems in locations that will achieve high capacity factors.

  6. Solution of hydraulic nets, by means of the application of the pattern of balance of nodes and the method of linealization of equations

    International Nuclear Information System (INIS)

    Narvaez Rincon, Paulo Cesar; Granados Jorge Armando, Barrera Hector

    1999-01-01

    The dimension of nets of fluids distribution is a common problem to different areas of the engineering, as the chemistry and the civil, present in the design of aqueducts, distribution systems of domiciliary gas, nets against fire and plants of chemical transformation. This work presents a model for its simulation, by means of the application of the balance of nodes and the theory of linealization of equations, it allows to know a complex net, in which they can be present, accessories, bombs, control valves, aspersion mouthpieces and process equipment. It is applicable to open, closed nets or combinations of two

  7. Convolutional neural networks with balanced batches for facial expressions recognition

    Science.gov (United States)

    Battini Sönmez, Elena; Cangelosi, Angelo

    2017-03-01

    This paper considers the issue of fully automatic emotion classification on 2D faces. In spite of the great effort done in recent years, traditional machine learning approaches based on hand-crafted feature extraction followed by the classification stage failed to develop a real-time automatic facial expression recognition system. The proposed architecture uses Convolutional Neural Networks (CNN), which are built as a collection of interconnected processing elements to simulate the brain of human beings. The basic idea of CNNs is to learn a hierarchical representation of the input data, which results in a better classification performance. In this work we present a block-based CNN algorithm, which uses noise, as data augmentation technique, and builds batches with a balanced number of samples per class. The proposed architecture is a very simple yet powerful CNN, which can yield state-of-the-art accuracy on the very competitive benchmark algorithm of the Extended Cohn Kanade database.

  8. Effect of drink carbohydrate content on postexercise gastric emptying, rehydration, and the calculation of net fluid balance.

    Science.gov (United States)

    Clayton, David J; Evans, Gethin H; James, Lewis J

    2014-02-01

    The purpose of this study was to examine the gastric emptying and rehydration effects of hypotonic and hypertonic glucose-electrolyte drinks after exercise-induced dehydration. Eight healthy males lost ~1.8% body mass by intermittent cycling and rehydrated (150% of body mass loss) with a hypotonic 2% (2% trial) or a hypertonic 10% (10% trial) glucose-electrolyte drink over 60 min. Blood and urine samples were taken at preexercise, postexercise, and 60, 120, 180, and 240 min postexercise. Gastric and test drink volume were determined 15, 30, 45, 60, 90, and 120 min postexercise. At the end of the gastric sampling period 0.3% (2% trial) and 42.1% (10% trial; p rehydration drink might be mediated by a slower rate of gastric emptying, but the slow gastric emptying of such solutions makes rehydration efficiency difficult to determine in the hours immediately after drinking, compromising the calculation of net fluid balance.

  9. Asymmetric warming significantly affects net primary production, but not ecosystem carbon balances of forest and grassland ecosystems in northern China.

    Science.gov (United States)

    Su, Hongxin; Feng, Jinchao; Axmacher, Jan C; Sang, Weiguo

    2015-03-13

    We combine the process-based ecosystem model (Biome-BGC) with climate change-scenarios based on both RegCM3 model outputs and historic observed trends to quantify differential effects of symmetric and asymmetric warming on ecosystem net primary productivity (NPP), heterotrophic respiration (Rh) and net ecosystem productivity (NEP) of six ecosystem types representing different climatic zones of northern China. Analysis of covariance shows that NPP is significant greater at most ecosystems under the various environmental change scenarios once temperature asymmetries are taken into consideration. However, these differences do not lead to significant differences in NEP, which indicates that asymmetry in climate change does not result in significant alterations of the overall carbon balance in the dominating forest or grassland ecosystems. Overall, NPP, Rh and NEP are regulated by highly interrelated effects of increases in temperature and atmospheric CO2 concentrations and precipitation changes, while the magnitude of these effects strongly varies across the six sites. Further studies underpinned by suitable experiments are nonetheless required to further improve the performance of ecosystem models and confirm the validity of these model predictions. This is crucial for a sound understanding of the mechanisms controlling the variability in asymmetric warming effects on ecosystem structure and functioning.

  10. Asymmetric warming significantly affects net primary production, but not ecosystem carbon balances of forest and grassland ecosystems in northern China

    Science.gov (United States)

    Su, Hongxin; Feng, Jinchao; Axmacher, Jan C.; Sang, Weiguo

    2015-03-01

    We combine the process-based ecosystem model (Biome-BGC) with climate change-scenarios based on both RegCM3 model outputs and historic observed trends to quantify differential effects of symmetric and asymmetric warming on ecosystem net primary productivity (NPP), heterotrophic respiration (Rh) and net ecosystem productivity (NEP) of six ecosystem types representing different climatic zones of northern China. Analysis of covariance shows that NPP is significant greater at most ecosystems under the various environmental change scenarios once temperature asymmetries are taken into consideration. However, these differences do not lead to significant differences in NEP, which indicates that asymmetry in climate change does not result in significant alterations of the overall carbon balance in the dominating forest or grassland ecosystems. Overall, NPP, Rh and NEP are regulated by highly interrelated effects of increases in temperature and atmospheric CO2 concentrations and precipitation changes, while the magnitude of these effects strongly varies across the six sites. Further studies underpinned by suitable experiments are nonetheless required to further improve the performance of ecosystem models and confirm the validity of these model predictions. This is crucial for a sound understanding of the mechanisms controlling the variability in asymmetric warming effects on ecosystem structure and functioning.

  11. An Analytical Time–Domain Expression for the Net Ripple Produced by Parallel Interleaved Converters

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, Brian B.; Krein, Philip T.

    2017-03-01

    We apply modular arithmetic and Fourier series to analyze the superposition of N interleaved triangular waveforms with identical amplitudes and duty-ratios. Here, interleaving refers to the condition when a collection of periodic waveforms with identical periods are each uniformly phase-shifted across one period. The main result is a time-domain expression which provides an exact representation of the summed and interleaved triangular waveforms, where the peak amplitude and parameters of the time-periodic component are all specified in closed-form. Analysis is general and can be used to study various applications in multi-converter systems. This model is unique not only in that it reveals a simple and intuitive expression for the net ripple, but its derivation via modular arithmetic and Fourier series is distinct from prior approaches. The analytical framework is experimentally validated with a system of three parallel converters under time-varying operating conditions.

  12. Multi-Ethnicity in the Malaysian Workplace: The Net Balance of 35 Years of Affirmative Policies as Observed by a Foreign Visitor

    Science.gov (United States)

    Montesino, Max U.

    2007-01-01

    This paper looks at the net societal balance of post-independence affirmative action policies in Malaysia. Social imbalances prompted the country to implement affirmative policies to uplift the majority natives (Malays, Indigenous people of Sabah and Sarawak, etc.). These policies were reluctantly accepted by the immigrant communities (Chinese,…

  13. Expression of aggrecan components in perineuronal nets in the mouse cerebral cortex

    Directory of Open Access Journals (Sweden)

    Hiroshi Ueno

    2018-06-01

    Full Text Available Specific regions of the cerebral cortex are highly plastic in an organism’s lifetime. It is thought that perineuronal nets (PNNs regulate plasticity, but labeling for Wisteria floribunda agglutinin (WFA, which is widely used to detect PNNs, is observed throughout the cortex. The aggrecan molecule—a PNN component—may regulate plasticity, and may also be involved in determining region-specific vulnerability to stress. To clarify cortical region-specific plasticity and vulnerability, we qualitatively analyzed aggrecan-positive and glycosylated aggrecan-positive PNNs in the mature mouse cerebral cortex. Our findings revealed the selective expression of both aggrecan-positive and glycosylated aggrecan-positive PNNs in the cortex. WFA-positive PNNs expressed aggrecan in a region-specific manner in the cortex. Furthermore, we observed variable distributions of PNNs containing WFA- and aggrecan-positive molecules. Together, our findings suggest that PNN components and their function differ depending on the cortical region, and that aggrecan molecules may be involved in determining region-specific plasticity and vulnerability in the cortex. Keywords: Aggrecan, Brain region-specific, Chondroitin sulfate proteoglycan, Extracellular matrix, Perineuronal nets, Plasticity

  14. Bowen ratio/energy balance technique for estimating crop net CO2 assimilation, and comparison with a canopy chamber

    Science.gov (United States)

    Held, A. A.; Steduto, P.; Orgaz, F.; Matista, A.; Hsiao, T. C.

    1990-12-01

    This paper describes a Bowen ratio/energy balance (BREB) system which, in conjunction with an infra-red gas analyzer (IRGA), is referred to as BREB+ and is used to estimate evapotranspiration ( ET) and net CO2 flux ( NCF) over crop canopies. The system is composed of a net radiometer, soil heat flux plates, two psychrometers based on platinum resistance thermometers (PRT), bridge circuits to measure resistances, an IRGA, air pumps and switching valves, and a data logger. The psychrometers are triple shielded and aspirated, and with aspiration also between the two inner shields. High resistance (1 000 ohm) PRT's are used for dry and wet bulbs to minimize errors due to wiring and connector resistances. A high (55 K ohm) fixed resistance serves as one arm of the resistance bridge to ensure linearity in output signals. To minimize gaps in data, to allow measurements at short (e.g., 5 min) intervals, and to simplify operation, the psychrometers were fixed at their upper and lower position over the crop and not alternated. Instead, the PRT's, connected to the bridge circuit and the data logger, were carefully calibrated together. Field tests using a common air source showed appartent effects of the local environment around each psychrometer on the temperatures measured. ET rates estimated with the BREB system were compared to those measured with large lysimeters. Daily totals agreed within 5%. There was a tendency, however, for the lysimeter measurements to lag behind the BREB measurements. Daily patterns of NCF estimated with the BREB+ system are consistent with expectations from theories and data in the literature. Side-by-side comparisons with a stirred Mylar canopy chamber showed similar NCF patterns. On the other hand, discrepancies between the results of the two methods were quite marked in the morning or afternoon on certain dates. Part of the discrepancies may be attributed to inaccuracies in the psychrometric temperature measurements. Other possible causes

  15. BALANCE

    Science.gov (United States)

    Carmichael, H.

    1953-01-01

    A torsional-type analytical balance designed to arrive at its equilibrium point more quickly than previous balances is described. In order to prevent external heat sources creating air currents inside the balance casing that would reiard the attainment of equilibrium conditions, a relatively thick casing shaped as an inverted U is placed over the load support arms and the balance beam. This casing is of a metal of good thernnal conductivity characteristics, such as copper or aluminum, in order that heat applied to one portion of the balance is quickly conducted to all other sensitive areas, thus effectively preventing the fornnation of air currents caused by unequal heating of the balance.

  16. Gene expression prediction by soft integration and the elastic net-best performance of the DREAM3 gene expression challenge.

    Directory of Open Access Journals (Sweden)

    Mika Gustafsson

    Full Text Available BACKGROUND: To predict gene expressions is an important endeavour within computational systems biology. It can both be a way to explore how drugs affect the system, as well as providing a framework for finding which genes are interrelated in a certain process. A practical problem, however, is how to assess and discriminate among the various algorithms which have been developed for this purpose. Therefore, the DREAM project invited the year 2008 to a challenge for predicting gene expression values, and here we present the algorithm with best performance. METHODOLOGY/PRINCIPAL FINDINGS: We develop an algorithm by exploring various regression schemes with different model selection procedures. It turns out that the most effective scheme is based on least squares, with a penalty term of a recently developed form called the "elastic net". Key components in the algorithm are the integration of expression data from other experimental conditions than those presented for the challenge and the utilization of transcription factor binding data for guiding the inference process towards known interactions. Of importance is also a cross-validation procedure where each form of external data is used only to the extent it increases the expected performance. CONCLUSIONS/SIGNIFICANCE: Our algorithm proves both the possibility to extract information from large-scale expression data concerning prediction of gene levels, as well as the benefits of integrating different data sources for improving the inference. We believe the former is an important message to those still hesitating on the possibilities for computational approaches, while the latter is part of an important way forward for the future development of the field of computational systems biology.

  17. Net expression inhibits the growth of pancreatic ductal adenocarcinoma cell PL45 in vitro and in vivo.

    Directory of Open Access Journals (Sweden)

    Baiwen Li

    Full Text Available Pancreatic ductal adenocarcinoma has a poor prognosis due to late diagnosis and a lack of effective therapeutic options. Thus, it is important to better understand its molecular mechanisms and to develop more effective treatments for the disease. The ternary complex factor Net, which exerts its strong inhibitory function on transcription of proto-oncogene gene c-fos by forming ternary complexes with a second transcription factor, has been suspected of being involved in pancreatic cancer and other tumors biology. In this study, we found that the majority of pancreatic ductal adenocarcinoma tissues and cell lines had weak or no expression of Net, whereas significantly high level of Net expression occurred in paired adjacent normal tissues we studied. Furthermore, using in vitro and in vivo model systems, we found that overexpression of Net inhibited cell growth and survival and induced cell apoptosis in human pancreatic ductal adenocarcinoma cell PL45; the mechanisms by which Net inhibited the cell cycle progression were mainly through P21-Cyclin D1/CDK4 Pathway. Our data thus suggested that Net might play an important role in pancreatic carcinogenesis, possibly by acting as a tumor suppressor gene.

  18. Cellular MYCro economics: Balancing MYC function with MYC expression.

    Science.gov (United States)

    Levens, David

    2013-11-01

    The expression levels of the MYC oncoprotein have long been recognized to be associated with the outputs of major cellular processes including proliferation, cell growth, apoptosis, differentiation, and metabolism. Therefore, to understand how MYC operates, it is important to define quantitatively the relationship between MYC input and expression output for its targets as well as the higher-order relationships between the expression levels of subnetwork components and the flow of information and materials through those networks. Two different views of MYC are considered, first as a molecular microeconomic manager orchestrating specific positive and negative responses at individual promoters in collaboration with other transcription and chromatin components, and second, as a macroeconomic czar imposing an overarching rule onto all active genes. In either case, c-myc promoter output requires multiple inputs and exploits diverse mechanisms to tune expression to the appropriate levels relative to the thresholds of expression that separate health and disease.

  19. Relationships between net primary productivity and stand age for several forest types and their influence on China's carbon balance.

    Science.gov (United States)

    Wang, Shaoqiang; Zhou, Lei; Chen, Jingming; Ju, Weimin; Feng, Xianfeng; Wu, Weixing

    2011-06-01

    Affected by natural and anthropogenic disturbances such as forest fires, insect-induced mortality and harvesting, forest stand age plays an important role in determining the distribution of carbon pools and fluxes in a variety of forest ecosystems. An improved understanding of the relationship between net primary productivity (NPP) and stand age (i.e., age-related increase and decline in forest productivity) is essential for the simulation and prediction of the global carbon cycle at annual, decadal, centurial, or even longer temporal scales. In this paper, we developed functions describing the relationship between national mean NPP and stand age using stand age information derived from forest inventory data and NPP simulated by the BEPS (Boreal Ecosystem Productivity Simulator) model in 2001. Due to differences in ecobiophysical characteristics of different forest types, NPP-age equations were developed for five typical forest ecosystems in China (deciduous needleleaf forest (DNF), evergreen needleleaf forest in tropic and subtropical zones (ENF-S), deciduous broadleaf forest (DBF), evergreen broadleaf forest (EBF), and mixed broadleaf forest (MBF)). For DNF, ENF-S, EBF, and MBF, changes in NPP with age were well fitted with a common non-linear function, with R(2) values equal to 0.90, 0.75, 0.66, and 0.67, respectively. In contrast, a second order polynomial was best suitable for simulating the change of NPP for DBF, with an R(2) value of 0.79. The timing and magnitude of the maximum NPP varied with forest types. DNF, EBF, and MBF reached the peak NPP at the age of 54, 40, and 32 years, respectively, while the NPP of ENF-S maximizes at the age of 13 years. The highest NPP of DBF appeared at 122 years. NPP was generally lower in older stands with the exception of DBF, and this particular finding runs counter to the paradigm of age-related decline in forest growth. Evaluation based on measurements of NPP and stand age at the plot-level demonstrates the reliability

  20. Optimal balance between energy demand and onsite energy generation for robust net zero energy buildings considering future scenarios

    NARCIS (Netherlands)

    Kotireddy, R.R.; Hoes, P.; Hensen, J.L.M.

    2015-01-01

    Net-zero energy buildings have usually very low energy demand, and consequently heating ventilation and air conditioning (HVAC) systems are designed and controlled to meet this low energy demand. However, a number of uncertainties in the building use, operation and external conditions such as

  1. Treatment of neuroendocrine tumors (NETs) expressing SMT 90Y and 177Lu

    International Nuclear Information System (INIS)

    Oliva González, Juan P.; Baum, Richard

    2016-01-01

    Neuroendocrine tumors (NETs) are a relatively rare and extremely heterogeneous group, essentially characterized by a different metabolism and endocrine histologically pattern. NETs are a challenge for physicians not only for diagnosis but also for early treatment. In addition to this, QT or RT treatments that require a high rate of cell proliferation to be effective, they are not in these tumors as slow growth. The primary treatment of NETs is surgery, either with a curative intent or tumor shrinkage. Peptide Receptors Radiotherapy (RTPR) consists of the administration for therapeutic purposes of Radiolabeled Synthetic Peptides that bind specifically and with high affinity to receptors of tumor cells. The RTPR of TNE with SMT analogues is effective for handling or metastizados inoperable patients. The Conference gives an accurate picture of the treatment of these tumors both 90 Y as 177 Lu. (author)

  2. Shifting the Arctic Carbon Balance: Effects of a Long-Term Fertilization Experiment and Anomalously Warm Temperatures on Net Ecosystem Exchange in the Alaskan Tundra

    Science.gov (United States)

    Ludwig, S.; Natali, S.; Rastetter, E. B.; Shaver, G. R.; Graham, L. M.; Jastrow, J. D.

    2017-12-01

    The arctic is warming at an accelerated rate relative to the globe. Among the predicted consequences of warming temperatures in the arctic are increased gross primary productivity (GPP), ecosystem respiration (ER), and nutrient availability. The net effect of these changes on the carbon (C) cycle and resulting C balance and feedback to climate change remain unclear. Historically the Arctic has been a C sink, but evidence from recent years suggests some regions in the Arctic are becoming C sources. To predict the role of the Arctic in global C cycling, the mechanisms affecting arctic C balances need to be better resolved. We measured net ecosystem exchange (NEE) in a long-term, multi-level, fertilization experiment at Toolik Lake, AK during an anomalously warm summer. We modeled NEE, ER, and GPP using a Bayesian network model. The best-fit model included Q10 temperature functions and linear fertilization functions for both ER and GPP. ER was more strongly affected by temperature and GPP was driven more by fertilization level. As a result, fertilization increased the C sink capacity, but only at moderate and low temperatures. At high temperatures (>28 °C) the NEE modeled for the highest level of fertilization was not significantly different from zero. In contrast, at ambient nutrient levels modeled NEE was significantly below zero (net uptake) until 35 °C, when it becomes neutral. Regardless of the level of fertilization, NEE never decreased with warming. Temperature in low ranges (5-15°C) had no net effect on NEE, whereas NEE began to increase exponentially with temperature after a threshold of 15°C until becoming a net source to the atmosphere at 37°C. Our results indicate that the C sink strength of tundra ecosystems can be increased with small increases in nutrient availability, but that large increase in nutrient availability can switch tundra ecosystems into C sources under warm conditions. Warming temperatures in tundra ecosystems will only decrease C

  3. Evaluating algorithms for the Generation of Referring Expressions using a balanced corpus

    NARCIS (Netherlands)

    Gatt, A.; van der Sluis, Ielka; van Deemter, Kees

    2007-01-01

    Despite being the focus of intensive research, evaluation of algorithms that generate referring expressions is still in its infancy. We describe a corpusbased evaluation methodology, applied to a number of classic algorithms in this area. The methodology focuses on balance and semantic transparency

  4. XML as a format of expression of Object-Oriented Petri Nets

    Directory of Open Access Journals (Sweden)

    Petr Jedlička

    2004-01-01

    Full Text Available A number of object-oriented (OO variants have so far been devised for Petri Nets (PN. However, none of these variants has ever been described using an open, independent format – such as XML. This article suggests several possibilities and advantages of such a description. The outlined XML language definition for the description of object-oriented Petri Nets (OOPN is based on XMI (description of UML object-oriented models, SOX (simple description of general OO systems and PNML (an XML-based language used for the description of structured and modular PN. For OOPN, the XML form of description represents a standard format for storing as well as for transfer between various OOPN-processing (analysis, simulation, ... tools.

  5. Net soil respiration and greenhouse gas balance along a sequence of forest disturbance to smallholder rubber and oil palm plantations in Sumatra

    Science.gov (United States)

    Khusyu Aini, Fitri; Hergoualc'h, Kristell; Smith, Jo; Verchot, Louis; Martius, Christopher

    2017-04-01

    The rapid increase in demand for land to establish oil palm and rubber plantations has led to the conversion of forests, with potential impacts on greenhouse gas emissions and on climate change. This study evaluates the net greenhouse gas balance following forest change to other land uses, i.e. one year rubber plantation, twenty-year rubber plantation and eight year oil palm plantation on Sumatran mineral soils. None of the plantations had ever been fertilized previously. During this study they were fertilized to provide nitrogen at the recommended rate used by farmers (33.3 kg N ha-1 y-1). The ecosystem stores carbon in litterfall, standing litter biomass (undergrowth vegetation, leaves, twigs, litter on the soil surface), soil organic matter, root biomass, and standing tree biomass. It releases carbon to the atmosphere through soil respiration fluxes, negative values indicating that carbon is stored by the land use change and positive values indicating emissions to the atmosphere. Net soil respiration was assessed using a mass balance approach: standing litter and tree biomass were measured once; the rate of carbon accumulation from standing litter and tree biomass was calculated by dividing the stock by the age of plantation or the time since logging started in the disturbed forest. The carbon accumulation in standing litter, tree biomass in the forest and soil organic matter for all land-uses was estimated from available in the literature. Root biomass for each land-use system was calculated using the root:shoot ratio. The net soil respiration of carbon dioxide from the forest, disturbed forest, one year rubber plantation, twenty-year rubber plantation and oil palm plantation were calculated to be -6 (± 5), 12 (± 6), 11 (± 15), 10 (± 5), 39 (± 7) Mg ha-1 y-1, respectively. Soil nitrous oxide, methane and litterfall were measured for 14 months and respiration fluxes were measured for 5 months across land uses and different seasons. The measured emissions of

  6. Cross-impact balances. Applying pair interaction systems and multi-value Kauffman nets to multidisciplinary systems analysis

    Science.gov (United States)

    Weimer-Jehle, Wolfgang

    2008-06-01

    Cross-impact analysis is the name for a familiar method for multidisciplinary systems analysis in social sciences and management sciences, especially in technology foresight, technology assessment and scenario planning. A recently proposed form of cross-impact analysis, CIB, may be of interest for physicists, sociophysicists and complex network researchers because the CIB concept reveals considerable relations to some concepts of these research fields. This article describes the basics of CIB analysis framework, its applications in the social sciences, and its relations to the equilibrium points of pair interaction systems, random graphs, and generalized Kauffman nets. Therefore CIB can be seen as a merger of concepts originating in utterly different scientific fields. This may prove to be fruitful for both sides: For sociophysicists as an example of the application of complex network concepts in the social sciences and for cross-impact practitioners as a source of theoretical insights in the background of their tool.

  7. SUPPLEMENTARY FEEDING ON THE NUTRIENT BALANCE OF LACTATING DAIRY COW AT CONTRASTING TEMPERATURE REGIMES: ASSESSMENT USING CORNELL NET CARBOHYDRATE AND PROTEIN SYSTEM (CNCPS MODEL

    Directory of Open Access Journals (Sweden)

    A. Jayanegara

    2014-10-01

    Full Text Available Dairy cows often do not receive adequate nutrient supply during their lactation period. This condition caneven be worse if the environmental temperature is not in comfortable range which may occur especially intropical regions. The present research was aimed to simulate the effect of supplementary feeding on nutrientbalance of lactating dairy cow at contrasting temperature regimes using Cornell Net Carbohydrate andProtein System (CNCPS model. Treatments consisted of feeds (R1: Pennisetum purpureum, R2: P.purpureum + concentrate (60:40, R3: P. purpureum + Gliricidia sepium + Leucaena leucocephala(60:20:20, R4: P. purpureum + concentrate + G. sepium + L. leucocephala (60:20:10:10 and environmentaltemperatures (T1: 20 oC, T2: 30 oC. The dairy cow inputs in CNCPS were Holstein breed, body weight of500 kg, feed intake of 15 kg (dry matter basis per day and produced milk 15 kg/day. Based on the CNCPSmodel, there were negative balances of metabolisable energy (ME and metabolisable protein (MP if alactating dairy cow fed only by P. purpureum. The ME balance was worse at higher temperature, while theMP balance was remain unchanged. Addition of concentrate mixture (R2 fulfilled the ME and MPrequirements as well as other nutrients. Addition of leguminous tree leaves (R3 and R4 improved thenutritional status of the lactating cow model compared to R1, but did not better than R2. It was concludedthat supplementary feeding is necessary for improving the nutrient balance of lactating dairy cow, especiallywhen the cow is maintained under uncomfortable environmental temperature.

  8. Net Neutrality, the Fairness Doctrine, and the NRB: The Tension between United States Religious Expression and Media Regulation

    Directory of Open Access Journals (Sweden)

    Kathryn Montalbano

    2018-02-01

    Full Text Available This article analyzes the historical continuity between the opposition of the National Religious Broadcasters (NRB to the Fairness Doctrine (1949 and to the contemporary Federal Communications Commission (FCC Open Internet principle, net neutrality. These debates demonstrate how media policy discourse has shaped democratic ideals, including by designating whose voices are or are not included in broadcast and digital communication spaces. The discourse emerging from both media policy debates reveals that fears concerning cultural hegemony and the diversity of expression in the United States have intertwined with fears concerning the invasion of foreign ideologies. The article then considers the possibility of reconciling religious and secular discourse in the mediated public sphere.

  9. Net ecosystem production and organic carbon balance of U.S. East Coast estuaries: A synthesis approach

    Science.gov (United States)

    Herrmann, Maria; Najjar, Raymond G.; Kemp, W. Michael; Alexander, Richard B.; Boyer, Elizabeth W.; Cai, Wei-Jun; Griffith, Peter C.; Kroeger, Kevin D.; McCallister, S. Leigh; Smith, Richard A.

    2015-01-01

    Net ecosystem production (NEP) and the overall organic carbon budget for the estuaries along the East Coast of the United States are estimated. We focus on the open estuarine waters, excluding the fringing wetlands. We developed empirical models relating NEP to loading ratios of dissolved inorganic nitrogen to total organic carbon, and carbon burial in the sediment to estuarine water residence time and total nitrogen input across the landward boundary. Output from a data-constrained water quality model was used to estimate inputs of total nitrogen and organic carbon to the estuaries across the landward boundary, including fluvial and tidal-wetland sources. Organic carbon export from the estuaries to the continental shelf was computed by difference, assuming steady state. Uncertainties in the budget were estimated by allowing uncertainties in the supporting model relations. Collectively, U.S. East Coast estuaries are net heterotrophic, with the area-integrated NEP of −1.5 (−2.8, −1.0) Tg C yr−1 (best estimate and 95% confidence interval) and area-normalized NEP of −3.2 (−6.1, −2.3) mol C m−2 yr−1. East Coast estuaries serve as a source of organic carbon to the shelf, exporting 3.4 (2.0, 4.3) Tg C yr−1 or 7.6 (4.4, 9.5) mol C m−2 yr−1. Organic carbon inputs from fluvial and tidal-wetland sources for the region are estimated at 5.4 (4.6, 6.5) Tg C yr−1 or 12 (10, 14) mol C m−2 yr−1 and carbon burial in the open estuarine waters at 0.50 (0.33, 0.78) Tg C yr−1 or 1.1 (0.73, 1.7) mol C m−2 yr−1. Our results highlight the importance of estuarine systems in the overall coastal budget of organic carbon, suggesting that in the aggregate, U.S. East Coast estuaries assimilate (via respiration and burial) ~40% of organic carbon inputs from fluvial and tidal-wetland sources and allow ~60% to be exported to the shelf.

  10. Phytoplankton growth balanced by clam and zooplankton grazing and net transport into the low-salinity zone of the San Francisco Estuary

    Science.gov (United States)

    Kimmerer, Wim J.; Thompson, Janet K.

    2014-01-01

    We estimated the influence of planktonic and benthic grazing on phytoplankton in the strongly tidal, river-dominated northern San Francisco Estuary using data from an intensive study of the low salinity foodweb in 2006–2008 supplemented with long-term monitoring data. A drop in chlorophyll concentration in 1987 had previously been linked to grazing by the introduced clam Potamocorbula amurensis, but numerous changes in the estuary may be linked to the continued low chlorophyll. We asked whether phytoplankton continued to be suppressed by grazing and what proportion of the grazing was by benthic bivalves. A mass balance of phytoplankton biomass included estimates of primary production and grazing by microzooplankton, mesozooplankton, and clams. Grazing persistently exceeded net phytoplankton growth especially for larger cells, and grazing by microzooplankton often exceeded that by clams. A subsidy of phytoplankton from other regions roughly balanced the excess of grazing over growth. Thus, the influence of bivalve grazing on phytoplankton biomass can be understood only in the context of limits on phytoplankton growth, total grazing, and transport.

  11. Effect of propolis ethanol extract on myostatin gene expression and muscle morphometry of Nile tilapia in net cages.

    Science.gov (United States)

    Buck, E L; Mizubuti, I Y; Alfieri, A A; Otonel, R A A; Buck, L Y; Souza, F P; Prado-Calixto, O P; Poveda-Parra, A R; Alexandre Filho, L; Lopera-Barrero, N M

    2017-03-16

    Propolis can be used as growth enhancer due to its antimicrobial, antioxidant, and immune-stimulant properties, but its effects on morphometry and muscle gene expression are largely unknown. The present study evaluates the influence of propolis on muscle morphometry and myostatin gene expression in Nile tilapia (Oreochromis niloticus) bred in net cages. Reversed males (GIFT strain) with an initial weight of 170 ± 25 g were distributed in a (2 x 4) factorial scheme, with two diets (DPRO, commercial diet with 4% propolis ethanol extract and DCON, commercial diet without propolis, control) and four assessment periods (0, 35, 70, and 105 experimental days). Muscles were evaluated at each assessment period. Histomorphometric analysis classified the fiber diameters into four groups: 50 μm. RT-qPCR was performed to assess myostatin gene expression. Fibers 30 µm (30-50 and > 50 µm) at 70 days were 25.39% and 40.07% for DPRO and DCON, respectively. There was greater myostatin gene expression at 105 days, averaging 1.93 and 1.89 for DCON and DPRO, respectively, with no significant difference in any of the analyzed periods. Propolis ethanol extract did not affect the diameter of muscle fibers or the gene expression of myostatin. Future studies should describe the mechanisms of natural products' effects on muscle growth and development since these factors are highly relevant for fish production performance.

  12. Anaerobic digestion for methane generation and ammonia reforming for hydrogen production: A thermodynamic energy balance of a model system to demonstrate net energy feasibility

    International Nuclear Information System (INIS)

    Babson, David M.; Bellman, Karen; Prakash, Shaurya; Fennell, Donna E.

    2013-01-01

    During anaerobic digestion, organic matter is converted to carbon dioxide and methane, and organic nitrogen is converted to ammonia. Generally, ammonia is recycled as a fertilizer or removed via nitrification–denitrification in treatment systems; alternatively it could be recovered and catalytically converted to hydrogen, thus supplying additional fuel. To provide a basis for further investigation, a theoretical energy balance for a model system that incorporates anaerobic digestion, ammonia separation and recovery, and conversion of the ammonia to hydrogen is reported. The model Anaerobic Digestion-Bioammonia to Hydrogen (ADBH) system energy demands including heating, pumping, mixing, and ammonia reforming were subtracted from the total energy output from methane and hydrogen to create an overall energy balance. The energy balance was examined for the ADBH system operating with a fixed feedstock loading rate with C:N ratios (gC/gN) ranging from 136 to 3 which imposed corresponding total ammonia nitrogen (TAN) concentrations of 20–10,000 mg/L. Normalizing total energy potential to the methane potential alone indicated that at a C:N ratio of 17, the energy output was greater for the ADBH system than from anaerobic digestion generating only methane. Decreasing the C:N ratio increased the methane content of the biogas comprising primarily methane to >80% and increased the ammonia stripping energy demand. The system required 23–34% of the total energy generated as parasitic losses with no energy integration, but when internally produced heat and pressure differentials were recovered, parasitic losses were reduced to between 8 and 17%. -- Highlights: •Modeled an integrated Anaerobic Digestion-Bioammonia to Hydrogen (ADBH) system. •Demonstrated positive net energy produced over a range of conditions by ADBH. •Demonstrated significant advantages of dual fuel recovery for energy gain by >20%. •Suggested system design considerations for energy recovery with

  13. Nitrogen fertilization of switchgrass increases biomass yield and improves net greenhouse gas balance in northern Michigan, U.S.A

    International Nuclear Information System (INIS)

    Nikiema, Paligwende; Rothstein, David E.; Min, Doo-Hong; Kapp, Christian J.

    2011-01-01

    Nitrogen (N) fertilization can increase bioenergy crop production; however, fertilizer production and application can contribute to greenhouse gas (GHG) emissions, potentially undermining the GHG benefits of bioenergy crops. The objective of this study was to evaluate the effects of N fertilization on GHG emissions and biomass production of switchgrass bioenergy crop, in northern Michigan. Nitrogen fertilization treatments included 0 kg ha -1 (control), 56 kg ha -1 (low) and 112 kg ha -1 (high) of N applied as urea. Soil fluxes of CO 2 , N 2 O and CH 4 were measured every two weeks using static chambers. Indirect GHG emissions associated with field activities, manufacturing and transport of fertilizer and pesticides were derived from the literature. Switchgrass aboveground biomass yield was evaluated at the end of the growing season. Nitrogen fertilization contributed little to soil GHG emissions; relative to the control, there were additional global warming potential of 0.7 Mg ha -1 y -1 and 1.5 Mg ha -1 y -1 as CO 2 equivalents (CO 2 eq), calculated using the IPCC values, in the low and high N fertilization treatments, respectively. However, N fertilization greatly stimulated CO 2 uptake by switchgrass, resulting in 1.5- and 2.5-fold increases in biomass yield in the low and high N fertilization treatments, respectively. Nitrogen amendments improved the net GHG benefits by 2.6 Mg ha -1 y -1 and 9.4 Mg ha -1 y -1 as CO 2 eq relative to the control. Results suggest that N fertilization of switchgrass in this region could reduce (15-50%) the land base needed for bioenergy production and decrease pressure on land for food and forage crop production. -- Highlights: → We examine the effects of N fertilization of switchgrass on GHG emissions. → Effects of N fertilization on biomass production of switchgrass bioenergy crop. → N fertilization contributed little to greenhouse gas emissions. → N fertilization greatly stimulated CO 2 uptake by the switchgrass. → N

  14. ExpNet: Landmark-Free, Deep, 3D Facial Expressions

    OpenAIRE

    Chang, Feng-Ju; Tran, Anh Tuan; Hassner, Tal; Masi, Iacopo; Nevatia, Ram; Medioni, Gerard

    2018-01-01

    We describe a deep learning based method for estimating 3D facial expression coefficients. Unlike previous work, our process does not relay on facial landmark detection methods as a proxy step. Recent methods have shown that a CNN can be trained to regress accurate and discriminative 3D morphable model (3DMM) representations, directly from image intensities. By foregoing facial landmark detection, these methods were able to estimate shapes for occluded faces appearing in unprecedented in-the-...

  15. Effects of noise-induced hearing loss on parvalbumin and perineuronal net expression in the mouse primary auditory cortex.

    Science.gov (United States)

    Nguyen, Anna; Khaleel, Haroun M; Razak, Khaleel A

    2017-07-01

    Noise induced hearing loss is associated with increased excitability in the central auditory system but the cellular correlates of such changes remain to be characterized. Here we tested the hypothesis that noise-induced hearing loss causes deterioration of perineuronal nets (PNNs) in the auditory cortex of mice. PNNs are specialized extracellular matrix components that commonly enwrap cortical parvalbumin (PV) containing GABAergic interneurons. Compared to somatosensory and visual cortex, relatively less is known about PV/PNN expression patterns in the primary auditory cortex (A1). Whether changes to cortical PNNs follow acoustic trauma remains unclear. The first aim of this study was to characterize PV/PNN expression in A1 of adult mice. PNNs increase excitability of PV+ inhibitory neurons and confer protection to these neurons against oxidative stress. Decreased PV/PNN expression may therefore lead to a reduction in cortical inhibition. The second aim of this study was to examine PV/PNN expression in superficial (I-IV) and deep cortical layers (V-VI) following noise trauma. Exposing mice to loud noise caused an increase in hearing threshold that lasted at least 30 days. PV and PNN expression in A1 was analyzed at 1, 10 and 30 days following the exposure. No significant changes were observed in the density of PV+, PNN+, or PV/PNN co-localized cells following hearing loss. However, a significant layer- and cell type-specific decrease in PNN intensity was seen following hearing loss. Some changes were present even at 1 day following noise exposure. Attenuation of PNN may contribute to changes in excitability in cortex following noise trauma. The regulation of PNN may open up a temporal window for altered excitability in the adult brain that is then stabilized at a new and potentially pathological level such as in tinnitus. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Assessing wildlife benefits and carbon storage from restored and natural coastal marshes in the Nisqually River Delta: Determining marsh net ecosystem carbon balance

    Science.gov (United States)

    Anderson, Frank; Bergamaschi, Brian; Windham-Myers, Lisamarie; Woo, Isa; De La Cruz, Susan; Drexler, Judith; Byrd, Kristin; Thorne, Karen M.

    2016-06-24

    Working in partnership since 1996, the U.S. Fish and Wildlife Service and the Nisqually Indian Tribe have restored 902 acres of tidally influenced coastal marsh in the Nisqually River Delta (NRD), making it the largest estuary-restoration project in the Pacific Northwest to date. Marsh restoration increases the capacity of the estuary to support a diversity of wildlife species. Restoration also increases carbon (C) production of marsh plant communities that support food webs for wildlife and can help mitigate climate change through long-term C storage in marsh soils.In 2015, an interdisciplinary team of U.S. Geological Survey (USGS) researchers began to study the benefits of carbon for wetland wildlife and storage in the NRD. Our primary goals are (1) to identify the relative importance of the different carbon sources that support juvenile chinook (Oncorhynchus tshawytscha) food webs and contribute to current and historic peat formation, (2) to determine the net ecosystem carbon balance (NECB) in a reference marsh and a restoration marsh site, and (3) to model the sustainability of the reference and restoration marshes under projected sea-level rise conditions along with historical vegetation change. In this fact sheet, we focus on the main C sources and exchanges to determine NECB, including carbon dioxide (CO2) uptake through plant photosynthesis, the loss of CO2 through plant and soil respiration, emissions of methane (CH4), and the lateral movement or leaching loss of C in tidal waters.

  17. Expression and Function of Transmembrane-4 Superfamily (Tetraspanin Proteins in Osteoclasts: Reciprocal Roles of Tspan-5 and NET-6 during Osteoclastogenesis

    Directory of Open Access Journals (Sweden)

    Kaori Iwai

    2007-01-01

    Conclusions: These data indicate that a diversity of tetraspanins is expressed in osteoclast precursors, and that cell fusion during osteoclastogenesis is regulated by cooperation of distinct tetraspanin family proteins such as Tspan-5 and NET-6. This study indicates that functional alterations of tetraspanin family proteins may have therapeutic potential in diseases where osteoclasts play a major role, such as rheumatoid arthritis and osteoporosis.

  18. Balancing gene expression without library construction via a reusable sRNA pool.

    Science.gov (United States)

    Ghodasara, Amar; Voigt, Christopher A

    2017-07-27

    Balancing protein expression is critical when optimizing genetic systems. Typically, this requires library construction to vary the genetic parts controlling each gene, which can be expensive and time-consuming. Here, we develop sRNAs corresponding to 15nt 'target' sequences that can be inserted upstream of a gene. The targeted gene can be repressed from 1.6- to 87-fold by controlling sRNA expression using promoters of different strength. A pool is built where six sRNAs are placed under the control of 16 promoters that span a ∼103-fold range of strengths, yielding ∼107 combinations. This pool can simultaneously optimize up to six genes in a system. This requires building only a single system-specific construct by placing a target sequence upstream of each gene and transforming it with the pre-built sRNA pool. The resulting library is screened and the top clone is sequenced to determine the promoter controlling each sRNA, from which the fold-repression of the genes can be inferred. The system is then rebuilt by rationally selecting parts that implement the optimal expression of each gene. We demonstrate the versatility of this approach by using the same pool to optimize a metabolic pathway (β-carotene) and genetic circuit (XNOR logic gate). © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  19. Caught in the competitive crossfire: safety-net providers balance margin and mission in a profit-driven health care market.

    Science.gov (United States)

    Cunningham, Peter J; Bazzoli, Gloria J; Katz, Aaron

    2008-01-01

    This paper describes how intensifying competitive pressures in the health system are simultaneously driving increased demand for safety-net care and taxing safety-net providers' ability to maintain the mission of serving all, regardless of ability to pay. Although safety-net providers adapted to previous challenges arising from managed care, health system pressures have been more intense and more generalized across different sectors in recent years than in the past. Providers are adopting some of the same strategies being used in the private sector to attract higher-paying patients and changing their "image" as a safety-net provider.

  20. Mammary gene expression profiles during an intramammary challenge reveal potential mechanisms linking negative energy balance with impaired immune response

    DEFF Research Database (Denmark)

    Moyes, Kasey; Drackley, J K; Morin, D E

    2010-01-01

    Our objective was to compare mammary tissue gene expression profiles during a Streptococcus uberis (S. uberis) mastitis challenge between lactating cows subjected to dietary-induced negative energy balance (NEB; n = 5) and cows fed ad libitum to maintain positive energy balance (PEB; n = 5...... 0.05), with 86 DEG up-regulated and 201 DEG down-regulated. Canonical pathways most affected by NEB were IL-8 Signaling (10 genes), Glucocorticoid Receptor Signaling (13), and NRF2-mediated Oxidative Stress Response (10). Among genes differentially expressed by NEB, Cell Growth and Proliferation (48...

  1. GEM2Net: from gene expression modeling to -omics networks, a new CATdb module to investigate Arabidopsis thaliana genes involved in stress response.

    Science.gov (United States)

    Zaag, Rim; Tamby, Jean Philippe; Guichard, Cécile; Tariq, Zakia; Rigaill, Guillem; Delannoy, Etienne; Renou, Jean-Pierre; Balzergue, Sandrine; Mary-Huard, Tristan; Aubourg, Sébastien; Martin-Magniette, Marie-Laure; Brunaud, Véronique

    2015-01-01

    CATdb (http://urgv.evry.inra.fr/CATdb) is a database providing a public access to a large collection of transcriptomic data, mainly for Arabidopsis but also for other plants. This resource has the rare advantage to contain several thousands of microarray experiments obtained with the same technical protocol and analyzed by the same statistical pipelines. In this paper, we present GEM2Net, a new module of CATdb that takes advantage of this homogeneous dataset to mine co-expression units and decipher Arabidopsis gene functions. GEM2Net explores 387 stress conditions organized into 18 biotic and abiotic stress categories. For each one, a model-based clustering is applied on expression differences to identify clusters of co-expressed genes. To characterize functions associated with these clusters, various resources are analyzed and integrated: Gene Ontology, subcellular localization of proteins, Hormone Families, Transcription Factor Families and a refined stress-related gene list associated to publications. Exploiting protein-protein interactions and transcription factors-targets interactions enables to display gene networks. GEM2Net presents the analysis of the 18 stress categories, in which 17,264 genes are involved and organized within 681 co-expression clusters. The meta-data analyses were stored and organized to compose a dynamic Web resource. © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

  2. Understanding the pros and cons of organ donation decision-making: Decisional balance and expressing donation intentions among African Americans.

    Science.gov (United States)

    Flemming, Shauna St Clair; Redmond, Nakeva; Williamson, Dana Hz; Thompson, Nancy J; Perryman, Jennie P; Patzer, Rachel E; Arriola, Kimberly Jacob

    2018-04-01

    Increasing public commitment to organ donation is critical to improving donor kidney availability for end-stage renal disease patients desiring transplant. This study surveyed ( N = 1339) African Americans, measuring perceived pros relative to cons of organ donation, to evaluate an existing Transtheoretical Model decisional balance scale and associations between decisional balance and expressing donation intentions. Findings supported the existing scale structure. More positive decisional balance ratios were associated with 1.76 times the odds of expressing intentions (95% confidence interval = 1.52-2.04). Pros were more strongly linked to donation intentions than cons. Greater understanding of organ donation decision-making is valuable for informing interventions that encourage donation.

  3. net/files/pics/CEU.gif"/> The construction of work–life balance: The experience of Black employees in a call-centre environment

    OpenAIRE

    Sonia C.B. Potgieter; Antoni Barnard

    2010-01-01

    Orientation: Work–life balance, as a crucial aspect of employee and organisational wellness, remains an interesting field of research, especially due to the changing demographic employee profile.Research purpose: The objective of the study was to explore Black employees’ construction of work–life balance in a customer care environment.Motivation for the study: The conceptual debate regarding the construct of work–life balance in general as well as limited qualitative research with regard to B...

  4. PGC-1α expression in murine AgRP neurons regulates food intake and energy balance

    Directory of Open Access Journals (Sweden)

    Jonathan F. Gill

    2016-07-01

    Full Text Available Objective: Food intake and whole-body energy homeostasis are controlled by agouti-related protein (AgRP and pro-opiomelanocortin (POMC neurons located in the arcuate nucleus of the hypothalamus. Key energy sensors, such as the AMP-activated protein kinase (AMPK or sirtuin 1 (SIRT1, are essential in AgRP and POMC cells to ensure proper energy balance. In peripheral tissues, the transcriptional coactivator PGC-1α closely associates with these sensors to regulate cellular metabolism. The role of PGC-1α in the ARC nucleus, however, remains unknown. Methods: Using AgRP and POMC neurons specific knockout (KO mouse models we studied the consequences of PGC-1α deletion on metabolic parameters during fed and fasted states and on ghrelin and leptin responses. We also took advantage of an immortalized AgRP cell line to assess the impact of PGC-1α modulation on fasting induced AgRP expression. Results: PGC-1α is dispensable for POMC functions in both fed and fasted states. In stark contrast, mice carrying a specific deletion of PGC-1α in AgRP neurons display increased adiposity concomitant with significantly lower body temperature and RER values during nighttime. In addition, the absence of PGC-1α in AgRP neurons reduces food intake in the fed and fasted states and alters the response to leptin. Finally, both in vivo and in an immortalized AgRP cell line, PGC-1α modulates AgRP expression induction upon fasting. Conclusions: Collectively, our results highlight a role for PGC-1α in the regulation of AgRP neuronal functions in the control of food intake and peripheral metabolism. Author Video: Author Video Watch what authors say about their articles Keywords: PGC-1α, Agouti-related protein, Metabolism, Energy homeostasis, Pro-opiomelanocortin, Transcriptional regulation

  5. Effect of prolonged intravenous glucose and essential amino acid infusion on nitrogen balance, muscle protein degradation and ubiquitin-conjugating enzyme gene expression in calves

    Directory of Open Access Journals (Sweden)

    Scaife Jes R

    2008-02-01

    Full Text Available Abstract Background Intravenous infusions of glucose and amino acids increase both nitrogen balance and muscle accretion. We hypothesised that co-infusion of glucose (to stimulate insulin and essential amino acids (EAA would act additively to improve nitrogen balance by decreasing muscle protein degradation in association with alterations in muscle expression of components of the ubiquitin-proteasome proteolytic pathway. Methods We examined the effect of a 5 day intravenous infusions of saline, glucose, EAA and glucose + EAA, on urinary nitrogen excretion and muscle protein degradation. We carried out the study in 6 restrained calves since ruminants offer the advantage that muscle protein degradation can be assessed by excretion of 3 methyl-histidine and multiple muscle biopsies can be taken from the same animal. On the final day of infusion blood samples were taken for hormone and metabolite measurement and muscle biopsies for expression of ubiquitin, the 14-kDa E2 ubiquitin conjugating enzyme, and proteasome sub-units C2 and C8. Results On day 5 of glucose infusion, plasma glucose, insulin and IGF-1 concentrations were increased while urea nitrogen excretion and myofibrillar protein degradation was decreased. Co-infusion of glucose + EAA prevented the loss of urinary nitrogen observed with EAA infusions alone and enhanced the increase in plasma IGF-1 concentration but there was no synergistic effect of glucose + EAA on the decrease in myofibrillar protein degradation. Muscle mRNA expression of the ubiquitin conjugating enzyme, 14-kDa E2 and proteasome sub-unit C2 were significantly decreased, after glucose but not amino acid infusions, and there was no further response to the combined infusions of glucose + EAA. Conclusion Prolonged glucose infusion decreases myofibrillar protein degradation, prevents the excretion of infused EAA, and acts additively with EAA to increase plasma IGF-1 and improve net nitrogen balance. There was no evidence of

  6. Developmental switching in Physarum polycephalum : Petri net analysis of single cell trajectories of gene expression indicates responsiveness and genetic plasticity of the Waddington quasipotential landscape

    International Nuclear Information System (INIS)

    Werthmann, Britta; Marwan, Wolfgang

    2017-01-01

    The developmental switch to sporulation in Physarum polycephalum is a phytochrome-mediated far-red light-induced cell fate decision that synchronously encompasses the entire multinucleate plasmodial cell and is associated with extensive reprogramming of the transcriptome. By repeatedly taking samples of single cells after delivery of a light stimulus pulse, we analysed differential gene expression in two mutant strains and in a heterokaryon of the two strains all of which display a different propensity for making the cell fate decision. Multidimensional scaling of the gene expression data revealed individually different single cell trajectories eventually leading to sporulation. Characterization of the trajectories as walks through states of gene expression discretized by hierarchical clustering allowed the reconstruction of Petri nets that model and predict the observed behavior. Structural analyses of the Petri nets indicated stimulus- and genotype-dependence of both, single cell trajectories and of the quasipotential landscape through which these trajectories are taken. The Petri net-based approach to the analysis and decomposition of complex cellular responses and of complex mutant phenotypes may provide a scaffold for the data-driven reconstruction of causal molecular mechanisms that shape the topology of the quasipotential landscape. (paper)

  7. Developmental switching in Physarum polycephalum: Petri net analysis of single cell trajectories of gene expression indicates responsiveness and genetic plasticity of the Waddington quasipotential landscape

    Science.gov (United States)

    Werthmann, Britta; Marwan, Wolfgang

    2017-11-01

    The developmental switch to sporulation in Physarum polycephalum is a phytochrome-mediated far-red light-induced cell fate decision that synchronously encompasses the entire multinucleate plasmodial cell and is associated with extensive reprogramming of the transcriptome. By repeatedly taking samples of single cells after delivery of a light stimulus pulse, we analysed differential gene expression in two mutant strains and in a heterokaryon of the two strains all of which display a different propensity for making the cell fate decision. Multidimensional scaling of the gene expression data revealed individually different single cell trajectories eventually leading to sporulation. Characterization of the trajectories as walks through states of gene expression discretized by hierarchical clustering allowed the reconstruction of Petri nets that model and predict the observed behavior. Structural analyses of the Petri nets indicated stimulus- and genotype-dependence of both, single cell trajectories and of the quasipotential landscape through which these trajectories are taken. The Petri net-based approach to the analysis and decomposition of complex cellular responses and of complex mutant phenotypes may provide a scaffold for the data-driven reconstruction of causal molecular mechanisms that shape the topology of the quasipotential landscape.

  8. Understanding Net Zero Energy Buildings

    DEFF Research Database (Denmark)

    Salom, Jaume; Widén, Joakim; Candanedo, José

    2011-01-01

    Although several alternative definitions exist, a Net-Zero Energy Building (Net ZEB) can be succinctly described as a grid-connected building that generates as much energy as it uses over a year. The “net-zero” balance is attained by applying energy conservation and efficiency measures...... and by incorporating renewable energy systems. While based on annual balances, a complete description of a Net ZEB requires examining the system at smaller time-scales. This assessment should address: (a) the relationship between power generation and building loads and (b) the resulting interaction with the power grid...

  9. Expression of perilipins in human skeletal muscle in vitro and in vivo in relation to diet, exercise and energy balance

    DEFF Research Database (Denmark)

    Gjelstad, I M F; Haugen, F; Gulseth, H L

    2011-01-01

    , enhanced the expression of perilipin 2 and 3. Perilipin 1 mRNA correlated positively with body fat mass, whereas none of the perilipins were associated with insulin sensitivity. In conclusion, all perilipins mRNAs were expressed in human skeletal muscle. Diet as well as endurance exercise modulated......The perilipin proteins enclose intracellular lipid droplets. We describe the mRNA expression of the five perilipins in human skeletal muscle in relation to fatty acid supply, exercise and energy balance. We observed that all perilipins were expressed in skeletal muscle biopsies with the highest m......RNA levels of perilipin 2, 4 and 5. Cultured myotubes predominantly expressed perilipin 2 and 3. In vitro, incubation of myotubes with fatty acids enhanced mRNA expression of perilipin 1, 2 and 4. In vivo, low fat diet increased mRNA levels of perilipin 3 and 4. Endurance training, but not strength training...

  10. Dexmedetomidine attenuates pancreatic injury and inflammatory response in mice with pancreatitis by possible reduction of NLRP3 activation and up-regulation of NET expression.

    Science.gov (United States)

    Li, Yong; Pan, Yiyuan; Gao, Lin; Lu, Guotao; Zhang, Jingzhu; Xie, Xiaochun; Tong, Zhihui; Li, Baiqiang; Li, Gang; Li, Weiqin

    2018-01-22

    Previous studies have shown that acute inflammation is associated with increased sympathetic activity, which in turn increases the inflammatory response and leads to organ damage. The present study aimed to investigate whether dexmedetomidine administration during acute pancreatitis (AP) lessens pancreatic pathological and functional injury and the inflammatory response, and to explore the underlying mechanisms. Mild pancreatitis was induced in mice with caerulein, and severe pancreatitis was induced with caerulein plus lipopolysaccharide (LPS). After pancreatitis induction, dexmedetomidine at 10 or 20 μg/kg was injected via the tail vein. Pancreatic pathological and functional injury was assessed by histology and serum levels of amylase and lipase, respectively. The inflammatory response was evaluated by determining serum levels of inflammatory factors. The expression of myeloperoxidase (MPO) was examined by immunohistochemistry. The expression of norepinephrine transporter (NET), NLRP3, pro-IL-1β, and interleukin (IL)-1β in pancreatic tissue was detected by Western blot and real-time PCR. Dexmedetomidine at 20 μg/kg significantly attenuated pancreatic pathological injury, reduced serum levels of amylase, lipase, IL-1β, IL-6, and tumor necrosis factor (TNF)-α, and decreased the expression of MPO in pancreatic tissue in both mouse models of pancreatitis. In addition, dexmedetomidine at 20 μg/kg significantly down-regulated the expression of NLRP3, pro-IL-1β, and IL-1β in pancreatic tissue, but up-regulated the expression of NET in both mouse models. Dexmedetomidine attenuates pancreatic injury and inflammatory response in mice with pancreatitis possibly by reducing NLRP3 activation and up-regulating NET expression. Copyright © 2018 Elsevier Inc. All rights reserved.

  11. Petri Nets

    Indian Academy of Sciences (India)

    In a computer system, for example, typical discrete events ... This project brought out a series of influential reports on Petri net theory in the mid and late ... Technology became a leading centre for Petri net research and from then on, Petri nets ...

  12. SUPPLEMENTARY FEEDING ON THE NUTRIENT BALANCE OF LACTATING DAIRY COW AT CONTRASTING TEMPERATURE REGIMES: ASSESSMENT USING CORNELL NET CARBOHYDRATE AND PROTEIN SYSTEM (CNCPS) MODEL

    OpenAIRE

    A. Jayanegara; A. Sofyan

    2014-01-01

    Dairy cows often do not receive adequate nutrient supply during their lactation period. This condition caneven be worse if the environmental temperature is not in comfortable range which may occur especially intropical regions. The present research was aimed to simulate the effect of supplementary feeding on nutrientbalance of lactating dairy cow at contrasting temperature regimes using Cornell Net Carbohydrate andProtein System (CNCPS) model. Treatments consisted of feeds (R1: Pennisetum pur...

  13. Estimating agro-ecosystem carbon balance of northern Japan, and comparing the change in carbon stock by soil inventory and net biome productivity

    International Nuclear Information System (INIS)

    Li, Xi; Toma, Yo; Yeluripati, Jagadeesh; Iwasaki, Shinya; Bellingrath-Kimura, Sonoko D.; Jones, Edward O.; Hatano, Ryusuke

    2016-01-01

    Soil C sequestration in croplands is deemed to be one of the most promising greenhouse gas mitigation options for agriculture. We have used crop-level yields, modeled heterotrophic respiration (Rh) and land use data to estimate spatio-temporal changes in regional scale net primary productivity (NPP), plant C inputs, and net biome productivity (NBP) in northern Japan's arable croplands and grasslands for the period of 1959–2011. We compared the changes in C stocks derived from estimated NBP and using repeated inventory datasets for each individual land use type from 2005 to 2011. For the entire study region of 2193 ha, overall annual plant C inputs to the soil constituted 37% of total region NPP. Plant C inputs in upland areas (excluding bush/fallow) could be predicted by climate variables. Overall NBP for all land use types increased from − 1.26 Mg C ha"−"1 yr"−"1 in 1959–0.26 Mg C ha"−"1 yr"−"1 in 2011. However, upland and paddy fields showed a decreased in NBP over the period of 1959–2011, under the current C input scenario. From 1988, an increase in agricultural abandonment (bush/fallow) and grassland cover caused a slow increase in the regional C pools. The comparison of carbon budgets using the NBP estimation method and the soil inventory method indicated no significant difference between the two methods. Our results showed C loss in upland crops, paddy fields and sites that underwent land use change from paddy field to upland sites. We also show C gain in grassland from 2005 to 2011. An underestimation of NBP or an overestimation of repeated C inventories cannot be excluded, but either method may be suitable for tracking absolute changes in soil C, considering the uncertainty associated with these methods. - Highlights: • We compared C stocks change by two methods: (i) net biome productivity (NBP) and (ii) soil inventory. • Variation in net primary productivity (NPP), plant C input, NBP can be predicted by climate conditions. • NBP

  14. Estimating agro-ecosystem carbon balance of northern Japan, and comparing the change in carbon stock by soil inventory and net biome productivity

    Energy Technology Data Exchange (ETDEWEB)

    Li, Xi, E-mail: icy124@hotmail.com [School of Chemistry and Chemical Engineering, Southwest Petroleum University, Chengdu 610500 (China); Graduate school of Agriculture, Hokkaido University, Kita 9 Nishi 9, Kita-ku, Sapporo 060-8589 (Japan); Toma, Yo [Faculty of Agriculture, Ehime University, 3-5-7, Tarumi, Matsuyama 790-8566, Ehime (Japan); Yeluripati, Jagadeesh [The James Hutton Institute, Craigiebuckler, Aberdeen AB15 8QH, Scotland (United Kingdom); Iwasaki, Shinya [Graduate school of Agriculture, Hokkaido University, Kita 9 Nishi 9, Kita-ku, Sapporo 060-8589 (Japan); Bellingrath-Kimura, Sonoko D. [Leibniz Centre for Agricultural Landscape Research, Institute of Land Use Systems (Germany); Jones, Edward O. [Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London (United Kingdom); Hatano, Ryusuke [Graduate school of Agriculture, Hokkaido University, Kita 9 Nishi 9, Kita-ku, Sapporo 060-8589 (Japan)

    2016-06-01

    Soil C sequestration in croplands is deemed to be one of the most promising greenhouse gas mitigation options for agriculture. We have used crop-level yields, modeled heterotrophic respiration (Rh) and land use data to estimate spatio-temporal changes in regional scale net primary productivity (NPP), plant C inputs, and net biome productivity (NBP) in northern Japan's arable croplands and grasslands for the period of 1959–2011. We compared the changes in C stocks derived from estimated NBP and using repeated inventory datasets for each individual land use type from 2005 to 2011. For the entire study region of 2193 ha, overall annual plant C inputs to the soil constituted 37% of total region NPP. Plant C inputs in upland areas (excluding bush/fallow) could be predicted by climate variables. Overall NBP for all land use types increased from − 1.26 Mg C ha{sup −1} yr{sup −1} in 1959–0.26 Mg C ha{sup −1} yr{sup −1} in 2011. However, upland and paddy fields showed a decreased in NBP over the period of 1959–2011, under the current C input scenario. From 1988, an increase in agricultural abandonment (bush/fallow) and grassland cover caused a slow increase in the regional C pools. The comparison of carbon budgets using the NBP estimation method and the soil inventory method indicated no significant difference between the two methods. Our results showed C loss in upland crops, paddy fields and sites that underwent land use change from paddy field to upland sites. We also show C gain in grassland from 2005 to 2011. An underestimation of NBP or an overestimation of repeated C inventories cannot be excluded, but either method may be suitable for tracking absolute changes in soil C, considering the uncertainty associated with these methods. - Highlights: • We compared C stocks change by two methods: (i) net biome productivity (NBP) and (ii) soil inventory. • Variation in net primary productivity (NPP), plant C input, NBP can be predicted by climate

  15. A balance of FGF and BMP signals regulates cell cycle exit and Equarin expression in lens cells

    Science.gov (United States)

    Jarrin, Miguel; Pandit, Tanushree; Gunhaga, Lena

    2012-01-01

    In embryonic and adult lenses, a balance of cell proliferation, cell cycle exit, and differentiation is necessary to maintain physical function. The molecular mechanisms regulating the transition of proliferating lens epithelial cells to differentiated primary lens fiber cells are poorly characterized. To investigate this question, we used gain- and loss-of-function analyses to modulate fibroblast growth factor (FGF) and/or bone morphogenetic protein (BMP) signals in chick lens/retina explants. Here we show that FGF activity plays a key role for proliferation independent of BMP signals. Moreover, a balance of FGF and BMP signals regulates cell cycle exit and the expression of Ccdc80 (also called Equarin), which is expressed at sites where differentiation of lens fiber cells occurs. BMP activity promotes cell cycle exit and induces Equarin expression in an FGF-dependent manner. In contrast, FGF activity is required but not sufficient to induce cell cycle exit or Equarin expression. Furthermore, our results show that in the absence of BMP activity, lens cells have increased cell cycle length or are arrested in the cell cycle, which leads to decreased cell cycle exit. Taken together, these findings suggest that proliferation, cell cycle exit, and early differentiation of primary lens fiber cells are regulated by counterbalancing BMP and FGF signals. PMID:22718906

  16. Balance in Positive Emotional Expressivity across School Contexts Relates to Kindergartners' Adjustment

    Science.gov (United States)

    Hernández, Maciel M.; Eisenberg, Nancy; Valiente, Carlos; Spinrad, Tracy L.; Berger, Rebecca H.; VanSchyndel, Sarah K.; Thompson, Marilyn S.; Southworth, Jody; Silva, Kassondra M.

    2018-01-01

    Positive emotional expressivity has been associated with increased social competence and decreased maladjustment in childhood. However, a few researchers have found null or even positive associations between positive emotional expressivity and maladjustment, which suggests that there may be nuanced associations of positive expressivity, perhaps as…

  17. Net Neutrality

    DEFF Research Database (Denmark)

    Savin, Andrej

    2017-01-01

    Repealing “net neutrality” in the US will have no bearing on Internet freedom or security there or anywhere else.......Repealing “net neutrality” in the US will have no bearing on Internet freedom or security there or anywhere else....

  18. Estimating agro-ecosystem carbon balance of northern Japan, and comparing the change in carbon stock by soil inventory and net biome productivity.

    Science.gov (United States)

    Li, Xi; Toma, Yo; Yeluripati, Jagadeesh; Iwasaki, Shinya; Bellingrath-Kimura, Sonoko D; Jones, Edward O; Hatano, Ryusuke

    2016-06-01

    Soil C sequestration in croplands is deemed to be one of the most promising greenhouse gas mitigation options for agriculture. We have used crop-level yields, modeled heterotrophic respiration (Rh) and land use data to estimate spatio-temporal changes in regional scale net primary productivity (NPP), plant C inputs, and net biome productivity (NBP) in northern Japan's arable croplands and grasslands for the period of 1959-2011. We compared the changes in C stocks derived from estimated NBP and using repeated inventory datasets for each individual land use type from 2005 to 2011. For the entire study region of 2193 ha, overall annual plant C inputs to the soil constituted 37% of total region NPP. Plant C inputs in upland areas (excluding bush/fallow) could be predicted by climate variables. Overall NBP for all land use types increased from -1.26MgCha(-1)yr(-1) in 1959-0.26 Mg Cha(-1)yr(-1) in 2011. However, upland and paddy fields showed a decreased in NBP over the period of 1959-2011, under the current C input scenario. From 1988, an increase in agricultural abandonment (bush/fallow) and grassland cover caused a slow increase in the regional C pools. The comparison of carbon budgets using the NBP estimation method and the soil inventory method indicated no significant difference between the two methods. Our results showed C loss in upland crops, paddy fields and sites that underwent land use change from paddy field to upland sites. We also show C gain in grassland from 2005 to 2011. An underestimation of NBP or an overestimation of repeated C inventories cannot be excluded, but either method may be suitable for tracking absolute changes in soil C, considering the uncertainty associated with these methods. Copyright © 2016 Elsevier B.V. All rights reserved.

  19. Petri Nets

    Indian Academy of Sciences (India)

    GENERAL I ARTICLE ... In Part 1 of this two-part article, we have seen im- ..... mable logic controller and VLSI arrays, office automation systems, workflow management systems, ... complex discrete event and real-time systems; and Petri nets.

  20. Reduction in cortical parvalbumin expression due to intermittent theta-burst stimulation correlates with maturation of the perineuronal nets in young rats.

    Science.gov (United States)

    Mix, Annika; Hoppenrath, Kathrin; Funke, Klaus

    2015-01-01

    We recently showed that intermittent theta-burst stimulation (iTBS) using transcranial magnetic stimulation strongly reduces the number of rat neocortical interneurons expressing glutamic acid decarboxylase 67 kDa (GAD67) and parvalbumin (PV), indicating changed activity of fast-spiking (FS) interneurons. In advance of in vitro studies intended to characterize changes in electrical properties of FS interneurons under these conditions, we tested whether the iTBS effect is age-dependent. Conscious Sprague-Dawley rats aged between 28 and 90 days received three blocks of iTBS at 15 min intervals. We found that iTBS-related reduction in PV+ cells was absent up to an age of 32 days, then gradually increased, and approached a maximum of about 40% reduction at an age of about 40 days. The relative number of cells expressing PV (PV+, 8-9%) did not change with age in sham-controls and also the increase in cortical c-Fos expression induced by iTBS was not principally age-dependent. However, a prominent growth of the perineuronal nets, typically surrounding the PV+ cells, exactly paralleled the increase in the iTBS effect. Based on these findings, we conclude that the functional development of the inhibitory network of PV+ interneurons with regard to intracortical synaptic connectivity is not sufficiently matured in rats younger than 35 d to enable activity-dependent modifications during iTBS. Outgrowth of the perineuronal nets and associated maturation of excitatory cortical inputs, as is characteristic for the critical cortical period, may take place before PV+ interneurons can be sufficiently activated via repetitive transcranial magnetic stimulation, allowing plastic changes of molecular phenotype and likely also synaptic plasticity. © 2014 Wiley Periodicals, Inc.

  1. Gene expression of placental hormones regulating energy balance in small for gestational age neonates.

    Science.gov (United States)

    Struwe, Ellen; Berzl, Gabriele M; Schild, Ralf L; Dötsch, Jörg

    2009-01-01

    Fetal growth restriction is associated with an increased risk for metabolic and cardiovascular disease in later life. To further elucidate mechanisms that might be involved in the process of prenatal programming, we measured the adipokines leptin, resistin, and adiponectin and the GH-releasing hormone ghrelin in the placenta of small for gestational age (SGA) neonates. The control group included 24 placentas of appropriate for gestational age (AGA) newborns, in the study group were 16 placentas of SGA neonates. Gene expression of leptin, resistin, adiponectin, and ghrelin was examined. For hormones showing alterations in gene regulation placental protein expression was measured by Western blot. Placental mRNA expression of leptin was significantly increased in SGA placentas (p=0.0035, related to beta-actin). Protein concentration was increased, as well. There were no differences in placental resistin, adiponectin, or ghrelin gene expressions between SGA neonates and controls. Leptin was the only hormone to demonstrate a significant inverse correlation with birth weight (r=-0.44, p=0.01). Adiponectin correlated significantly with leptin (r=0.53, p=0.0023) and ghrelin (r=0.50, p=0.0045). Placental leptin gene expression and protein concentration showed the expected increase in the SGA group. Leptin was inversely correlated with birth weight. Positive correlation of adiponectin with leptin and ghrelin expression suggests an interaction between these hormones in the placenta. However, the unchanged expression of resistin, adiponectin, and ghrelin in SGA placentas and the absence of correlation with birth weight cast doubt whether these hormones produced in the placenta play a key role in fetal programming.

  2. The overwhelming role of soil N2O emissions in net greenhouse gas balance of the U.S. Corn Belt: Modeling estimate of nitrogen fertilizer impacts

    Science.gov (United States)

    Lu, C.; Yu, Z.; Cao, P.; Tian, H.

    2017-12-01

    The Corn Belt of the Midwestern U.S. is one of the most productive systems in the world during the growing season, with gross primary production exceeding even that of the Amazon forests. Fueled by increased commodity prices in the late 2000s, the area in corn and soybean in the U.S. has reached record highs with most of the newly added cropland converted from grasslands, wetland, and Conservation Reserve Program land. Intensive management practices, such as fertilizer use, irrigation, tillage, residue removal etc., have been implemented following cropland expansion to maximize crop yield from converted marginal land or from more monoculture production. The Corn Belt has been recognized as one of the major contributors to carbon sinks in the U.S., partially because crop harvest and residue removal reduced soil respiration. In the meanwhile, 75% of the total N2O emission in the U.S. comes from agriculture, among which the Corn Belt is the major source due to nitrogen management, and has large potential of climate mitigation. However, it remains far from certain how intensive cropland expansion and management practices in this region have affected soil carbon accumulation and non-CO2 GHG emissions. In this study, by using a process-based land ecosystem model, Dynamic Land Ecosystem Model (DLEM), we investigated the impacts of nitrogen fertilizer use on soil carbon accumulation and direct N2O emissions across the U.S. Corn Belt. Surprisingly, we found N fertilizer-induced SOC storage continued shrinking after the 1980s while N2O emissions remains relatively constant. The N fertilizer use led to a net greenhouse gas release since 2000 in both the western and eastern Corn Belt, contributing to climate warming. This study implies an increasing importance of nitrogen management for both agricultural production and climate mitigation.

  3. Combining feed-in tariffs and net-metering schemes to balance development in adoption of photovoltaic energy: Comparative economic assessment and policy implications for European countries

    International Nuclear Information System (INIS)

    Ramírez, F. Javier; Honrubia-Escribano, A.; Gómez-Lázaro, E.; Pham, Duc T.

    2017-01-01

    In the last fifteen years, Europe has been involved in the major development of photovoltaic (PV) solar energy. The Kyoto Protocol requirements and the European Union (EU) directives to promote the use of renewable energy sources (RES) together with environmental policies introduced for the development and use of alternative energies have generated a large number of market opportunities for this sector. Differences in the application of energy policies have caused significant imbalances in electricity systems and distortion of electricity prices. The main concern of governments is to define the support schemes to be used and how to combine them in the most profitable manner. The aim of this paper is to provide a comparative cost-effectiveness assessment using feed-in tariffs (FiT) and net-metering (NM) schemes in some representative EU countries. The authors have developed an economic model to evaluate the profitability of PV projects combining these support schemes. Results show not only the circumstances under which solar energy is economically profitable, but also the kind of PV systems, locations, minimum levels of tariff prices and specific combination of support schemes that should be promoted. - Highlights: • Comparative cost-effectiveness assessment combining FiT and NM support schemes. • A minimum FiT is proposed in addition to traditional financial performance indicators. • Results show the specific combinations of support schemes that should be promoted. • This work can aid efficient energy policy making. • Model could be applied to other types of RES projects and other geographical areas.

  4. RESTful NET

    CERN Document Server

    Flanders, Jon

    2008-01-01

    RESTful .NET is the first book that teaches Windows developers to build RESTful web services using the latest Microsoft tools. Written by Windows Communication Foundation (WFC) expert Jon Flanders, this hands-on tutorial demonstrates how you can use WCF and other components of the .NET 3.5 Framework to build, deploy and use REST-based web services in a variety of application scenarios. RESTful architecture offers a simpler approach to building web services than SOAP, SOA, and the cumbersome WS- stack. And WCF has proven to be a flexible technology for building distributed systems not necessa

  5. Improved netting

    International Nuclear Information System (INIS)

    Bramley, A.; Clabburn, R.J.T.

    1976-01-01

    A method is described for producing netting composed of longitudinal and transverse threads of irradiation cross linked thermoplastic material, the threads being joined together at their crossings by moulded masses of cross linked thermoplastic material. The thread may be formed of polyethylene filaments, subjected to a radiation dose of 15 to 25 MR. The moulding can be conducted at 245 0 to 260 0 C or higher. The product is claimed to be an improved quality of netting, with bonds of increased strength between crossing threads. (U.K.)

  6. Alterations in expression of Cat-315 epitope of perineuronal nets during normal ageing, and its modulation by an open-channel NMDA receptor blocker, memantine.

    Science.gov (United States)

    Yamada, Jun; Ohgomori, Tomohiro; Jinno, Shozo

    2017-06-15

    The perineuronal net (PNN), a specialized aggregate of the extracellular matrix, is involved in neuroprotection against oxidative stress, which is now recognized as a major contributor to age-related decline in brain functions. In this study, we investigated the age-related molecular changes of PNNs using monoclonal antibody Cat-315, which recognizes human natural killer-1 (HNK-1) glycan on aggrecan-based PNNs. Western blot analysis showed that the expression levels of Cat-315 epitope in the hippocampus were higher in middle-aged (MA, 12-month-old) mice than in young adult (YA, 2-month-old) mice. Although there were no differences in the expression levels of Cat-315 epitope between old age (OA, 20-month-old) and MA mice, Cat-315 immunoreactivity was also detected in astrocytes of OA mice. To focus on Cat-315 epitope in PNNs, we used YA and MA mice in the following experiments. Optical disector analysis showed that there were no differences in the numbers of Cat-315-positive (Cat-315 + ) PNNs between YA and MA mice. Fluorescence intensity analysis indicated that Cat-315 immunoreactivity in PNNs increased with age in the dorsal hippocampus, which is mainly involved in cognitive functions. Administration of an open-channel blocker of NMDA receptor, memantine, reduced the expression levels of Cat-315 epitope in the hippocampus. Furthermore, the numbers of glutamatergic and GABAergic terminals colocalized with Cat-315 epitope around parvalbumin-positive neurons were decreased by memantine. These findings provide novel insight into the involvement of PNNs in normal brain ageing, and suggest that memantine may counteract the age-related alterations in expression levels of Cat-315 epitope via regulation of its subcellular localization. © 2017 Wiley Periodicals, Inc.

  7. Petri Nets

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 4; Issue 9. Petri Nets - Applications. Y Narahari. General Article Volume 4 Issue 9 September 1999 pp 44-52 ... Author Affiliations. Y Narahari1. Department of Computer Science and Automation, Indian Institute of Science, Bangalore 560 012, India.

  8. Net Gain

    International Development Research Centre (IDRC) Digital Library (Canada)

    Describing the effect of tax incentives for import, production, and sale of nets and insecticides; and ..... So far, China is the only country where a system for the routine treatment of ...... 1993), and the trials in Ecuador and Peru (Kroeger et al.

  9. A balance of Mad and Myc expression dictates larval cell apoptosis and adult stem cell development during Xenopus intestinal metamorphosis.

    Science.gov (United States)

    Okada, Morihiro; Miller, Thomas C; Wen, Luan; Shi, Yun-Bo

    2017-05-11

    The Myc/Mad/Max network has long been shown to be an important factor in regulating cell proliferation, death and differentiation in diverse cell types. In general, Myc-Max heterodimers activate target gene expression to promote cell proliferation, although excess of c-Myc can also induce apoptosis. In contrast, Mad competes against Myc to form Mad-Max heterodimers that bind to the same target genes to repress their expression and promote differentiation. The role of the Myc/Mad/Max network during vertebrate development, especially, the so-called postembryonic development, a period around birth in mammals, is unclear. Using thyroid hormone (T3)-dependent Xenopus metamorphosis as a model, we show here that Mad1 is induced by T3 in the intestine during metamorphosis when larval epithelial cell death and adult epithelial stem cell development take place. More importantly, we demonstrate that Mad1 is expressed in the larval cells undergoing apoptosis, whereas c-Myc is expressed in the proliferating adult stem cells during intestinal metamorphosis, suggesting that Mad1 may have a role in cell death during development. By using transcription activator-like effector nuclease-mediated gene-editing technology, we have generated Mad1 knockout Xenopus animals. This has revealed that Mad1 is not essential for embryogenesis or metamorphosis. On the other hand, consistent with its spatiotemporal expression profile, Mad1 knockout leads to reduced larval epithelial apoptosis but surprisingly also results in increased adult stem cell proliferation. These findings not only reveal a novel role of Mad1 in regulating developmental cell death but also suggest that a balance of Mad and Myc controls cell fate determination during adult organ development.

  10. Interleukin 6 deficiency modulates the hypothalamic expression of energy balance regulating peptides during pregnancy in mice.

    Science.gov (United States)

    Pazos, Patricia; Lima, Luis; Casanueva, Felipe F; Diéguez, Carlos; García, María C

    2013-01-01

    Pregnancy is associated with hyperphagia, increased adiposity and multiple neuroendocrine adaptations. Maternal adipose tissue secretes rising amounts of interleukin 6 (IL6), which acts peripherally modulating metabolic function and centrally increasing energy expenditure and reducing body fat. To explore the role of IL6 in the central mechanisms governing dam's energy homeostasis, early, mid and late pregnant (gestational days 7, 13 and 18) wild-type (WT) and Il6 knockout mice (Il6-KO) were compared with virgin controls at diestrus. Food intake, body weight and composition as well as indirect calorimetry measurements were performed in vivo. Anabolic and orexigenic peptides: neuropeptide Y (Npy) and agouti-related peptide (Agrp); and catabolic and anorectic neuropeptides: proopiomelanocortin (Pomc), corticotrophin and thyrotropin-releasing hormone (Crh and Trh) mRNA levels were determined by in situ hybridization. Real time-PCR and western-blot were used for additional tissue gene expression and protein studies. Non-pregnant Il6-KO mice were leaner than WT mice due to a decrease in fat but not in lean body mass. Pregnant Il6-KO mice had higher fat accretion despite similar body weight gain than WT controls. A decreased fat utilization in absence of Il6 might explain this effect, as shown by increased respiratory exchange ratio (RER) in virgin Il6-KO mice. Il6 mRNA levels were markedly enhanced in adipose tissue but reduced in hypothalamus of mid and late pregnant WT mice. Trh expression was also stimulated at gestational day 13 and lack of Il6 blunted this effect. Conversely, in late pregnant mice lessened hypothalamic Il6 receptor alpha (Il6ra), Pomc and Crh mRNA were observed. Il6 deficiency during this stage up-regulated Npy and Agrp expression, while restoring Pomc mRNA levels to virgin values. Together these results demonstrate that IL6/IL6Ra system modulates Npy/Agrp, Pomc and Trh expression during mouse pregnancy, supporting a role of IL6 in the central

  11. Linear Logic on Petri Nets

    DEFF Research Database (Denmark)

    Engberg, Uffe Henrik; Winskel, Glynn

    This article shows how individual Petri nets form models of Girard's intuitionistic linear logic. It explores questions of expressiveness and completeness of linear logic with respect to this interpretation. An aim is to use Petri nets to give an understanding of linear logic and give some apprai...

  12. Net Locality

    DEFF Research Database (Denmark)

    de Souza e Silva, Adriana Araujo; Gordon, Eric

    Provides an introduction to the new theory of Net Locality and the profound effect on individuals and societies when everything is located or locatable. Describes net locality as an emerging form of location awareness central to all aspects of digital media, from mobile phones, to Google Maps......, to location-based social networks and games, such as Foursquare and facebook. Warns of the threats these technologies, such as data surveillance, present to our sense of privacy, while also outlining the opportunities for pro-social developments. Provides a theory of the web in the context of the history...... of emerging technologies, from GeoCities to GPS, Wi-Fi, Wiki Me, and Google Android....

  13. A Sulfated Glycosaminoglycan Linkage Region is a Novel Type of Human Natural Killer-1 (HNK-1 Epitope Expressed on Aggrecan in Perineuronal Nets.

    Directory of Open Access Journals (Sweden)

    Keiko Yabuno

    Full Text Available Human natural killer-1 (HNK-1 carbohydrate (HSO3-3GlcAβ1-3Galβ1-4GlcNAc-R is highly expressed in the brain and required for learning and neural plasticity. We previously demonstrated that expression of the HNK-1 epitope is mostly abolished in knockout mice for GlcAT-P (B3gat1, a major glucuronyltransferase required for HNK-1 biosynthesis, but remained in specific regions such as perineuronal nets (PNNs in these mutant mice. Considering PNNs are mainly composed of chondroitin sulfate proteoglycans (CSPGs and regulate neural plasticity, GlcAT-P-independent expression of HNK-1 in PNNs is suggested to play a role in neural plasticity. However, the function, structure, carrier glycoprotein and biosynthetic pathway for GlcAT-P-irrelevant HNK-1 epitope remain unclear. In this study, we identified a unique HNK-1 structure on aggrecan in PNNs. To determine the biosynthetic pathway for the novel HNK-1, we generated knockout mice for GlcAT-S (B3gat2, the other glucuronyltransferase required for HNK-1 biosynthesis. However, GlcAT-P and GlcAT-S double-knockout mice did not exhibit reduced HNK-1 expression compared with single GlcAT-P-knockout mice, indicating an unusual biosynthetic pathway for the HNK-1 epitope in PNNs. Aggrecan was purified from cultured cells in which GlcAT-P and -S are not expressed and we determined the structure of the novel HNK-1 epitope using liquid chromatography/mass spectrometry (LC/MS as a sulfated linkage region of glycosaminoglycans (GAGs, HSO3-GlcA-Gal-Gal-Xyl-R. Taken together, we propose a hypothetical model where GlcAT-I, the sole glucuronyltransferase required for synthesis of the GAG linkage, is also responsible for biosynthesis of the novel HNK-1 on aggrecan. These results could lead to discovery of new roles of the HNK-1 epitope in neural plasticity.

  14. The Balance of Expression of Dihydroflavonol 4-reductase and Flavonol Synthase Regulates Flavonoid Biosynthesis and Red Foliage Coloration in Crabapples.

    Science.gov (United States)

    Tian, Ji; Han, Zhen-yun; Zhang, Jie; Hu, YuJing; Song, Tingting; Yao, Yuncong

    2015-07-20

    Red leaf color is an attractive trait of Malus families, including crabapple (Malus spp.); however, little is known about the molecular mechanisms that regulate the coloration. Dihydroflavonols are intermediates in the production of both colored anthocyanins and colorless flavonols, and this current study focused on the gene expression balance involved in the relative accumulation of these compounds in crabapple leaves. Levels of anthocyanins and the transcript abundances of the anthocyanin biosynthetic gene, dihydroflavonol 4-reductase (McDFR) and the flavonol biosynthetic gene, flavonol synthase (McFLS), were assessed during the leaf development in two crabapple cultivars, 'Royalty' and 'Flame'. The concentrations of anthocyanins and flavonols correlated with leaf color and we propose that the expression of McDFR and McFLS influences their accumulation. Further studies showed that overexpression of McDFR, or silencing of McFLS, increased anthocyanin production, resulting in red-leaf and red fruit peel phenotypes. Conversely, elevated flavonol production and green phenotypes in crabapple leaves and apple peel were observed when McFLS was overexpressed or McDFR was silenced. These results suggest that the relative activities of McDFR and McFLS are important determinants of the red color of crabapple leaves, via the regulation of the metabolic fate of substrates that these enzymes have in common.

  15. Energy Balance Regulating Neuropeptides Are Expressed through Pregnancy and Regulated by Interleukin-6 Deficiency in Mouse Placenta.

    Science.gov (United States)

    Pazos, Patricia; Lima, Luis; Diéguez, Carlos; García, María C

    2014-01-01

    The placenta produces a number of signaling molecules including metabolic and reproductive hormones as well as several inflammatory mediators. Among them, Interleukin-6 (IL-6), a well-known immune and metabolic regulator, acts peripherally modulating metabolic function and centrally increasing energy expenditure and reducing body fat. IL-6 interacts with key hypothalamic neuropeptidergic systems controlling energy homeostasis such as those producing the orexigenic/anabolic: neuropeptide Y (NPY) and agouti-related peptide (AgRP) and anorectic/catabolic neuropeptides: proopiomelanocortin (POMC) and cocaine and amphetamine regulated transcript (CART). Human and rat placenta have been identified as source of these neuropeptides, but their expression and regulation in murine placental tissues remain unknown. Therefore, placental mRNA levels of IL-6, NPY, AgRP, POMC, and CART at different pregnancy stages (gestational days 13, 15, and 18) were analyzed by real time PCR, as were the effect of IL-6 deficiency (IL-6 knockout mice) on their placental expression. Our results showed that placenta-derived neuropeptides were regulated by gestational age and IL-6 throughout the second half of mouse pregnancy. These data suggest that IL-6 may participate in the fine tune control of energy balance during pregnancy by extending its action as a metabolic signal to the main organ at the fetomaternal interface: the placenta.

  16. Energy Balance Regulating Neuropeptides Are Expressed through Pregnancy and Regulated by Interleukin-6 Deficiency in Mouse Placenta

    Directory of Open Access Journals (Sweden)

    Patricia Pazos

    2014-01-01

    Full Text Available The placenta produces a number of signaling molecules including metabolic and reproductive hormones as well as several inflammatory mediators. Among them, Interleukin-6 (IL-6, a well-known immune and metabolic regulator, acts peripherally modulating metabolic function and centrally increasing energy expenditure and reducing body fat. IL-6 interacts with key hypothalamic neuropeptidergic systems controlling energy homeostasis such as those producing the orexigenic/anabolic: neuropeptide Y (NPY and agouti-related peptide (AgRP and anorectic/catabolic neuropeptides: proopiomelanocortin (POMC and cocaine and amphetamine regulated transcript (CART. Human and rat placenta have been identified as source of these neuropeptides, but their expression and regulation in murine placental tissues remain unknown. Therefore, placental mRNA levels of IL-6, NPY, AgRP, POMC, and CART at different pregnancy stages (gestational days 13, 15, and 18 were analyzed by real time PCR, as were the effect of IL-6 deficiency (IL-6 knockout mice on their placental expression. Our results showed that placenta-derived neuropeptides were regulated by gestational age and IL-6 throughout the second half of mouse pregnancy. These data suggest that IL-6 may participate in the fine tune control of energy balance during pregnancy by extending its action as a metabolic signal to the main organ at the fetomaternal interface: the placenta.

  17. Altered energy balance and cytokine gene expression in a murine model of chronic infection with Toxoplasma gondii.

    Science.gov (United States)

    Arsenijevic, D; Girardier, L; Seydoux, J; Chang, H R; Dulloo, A G

    1997-05-01

    The temporal pattern of changes in energy balance and cytokine mRNA expression in spleen and brain were examined in a mouse model of infection with Toxoplasma gondii. During days 1-7 postinfection, food intake was unaltered, but energy expenditure was significantly increased, and this was associated with elevated tumor necrosis factor-alpha (TNF-alpha), interleukin (IL)-1, IL-5, and interferon (IFN)-gamma. The hypermetabolic state persisted during subsequent anorexia, whose onset coincided with elevated IL-2, and at the end of the acute phase of cachexia, the dual anorexic and hypermetabolic states were associated with the cytokines examined: TNF-alpha, IL-1 beta, IL-2, IL-4, IL-5, IL-6, IL-10, and IFN-gamma. In the chronic phase of the infection, the mice showed either partial weight recovery (gainers) or no weight regain (nongainers). The infected gainers, though still hypophagic, were no longer hypermetabolic, and their cytokine mRNA was no longer elevated, except for TNF-alpha and IL-10. In contrast, the infected nongainers continued to show both anoroxia and hypermetabolism, which were associated with elevations in all cytokines examined and particularly those of the TH2 profile (IL-4 and IL-5) and IL-6. Taken together, these studies reveal a distinct pattern of cytokine mRNA expression underlying 1) hypermetabolism vs. anorexia, 2) acute vs. chronic cachexia, and 3) stable weight loss vs. partial weight recovery.

  18. Cocaine Effects on Dopaminergic Transmission Depend on a Balance between Sigma-1 and Sigma-2 Receptor Expression.

    Science.gov (United States)

    Aguinaga, David; Medrano, Mireia; Vega-Quiroga, Ignacio; Gysling, Katia; Canela, Enric I; Navarro, Gemma; Franco, Rafael

    2018-01-01

    Sigma σ 1 and σ 2 receptors are targets of cocaine. Despite sharing a similar name, the two receptors are structurally unrelated and their physiological role is unknown. Cocaine increases the level of dopamine, a key neurotransmitter in CNS motor control and reward areas. While the drug also affects dopaminergic signaling by allosteric modulations exerted by σ 1 R interacting with dopamine D 1 and D 2 receptors, the potential regulation of dopaminergic transmission by σ 2 R is also unknown. We here demonstrate that σ 2 R may form heteroreceptor complexes with D 1 but not with D 2 receptors. Remarkably σ 1 , σ 2 , and D 1 receptors may form heterotrimers with particular signaling properties. Determination of cAMP levels, MAP kinase activation and label-free assays demonstrate allosteric interactions within the trimer. Importantly, the presence of σ 2 R induces bias in signal transduction as σ 2 R ligands increase cAMP signaling whereas reduce MAP kinase activation. These effects, which are opposite to those exerted via σ 1 R, suggest that the D 1 receptor-mediated signaling depends on the degree of trimer formation and the differential balance of sigma receptor and heteroreceptor expression in acute versus chronic cocaine consumption. Although the physiological role is unknown, the heteroreceptor complex formed by σ 1 , σ 2 , and D 1 receptors arise as relevant to convey the cocaine actions on motor control and reward circuits and as a key factor in acquisition of the addictive habit.

  19. Cocaine Effects on Dopaminergic Transmission Depend on a Balance between Sigma-1 and Sigma-2 Receptor Expression

    Directory of Open Access Journals (Sweden)

    David Aguinaga

    2018-02-01

    Full Text Available Sigma σ1 and σ2 receptors are targets of cocaine. Despite sharing a similar name, the two receptors are structurally unrelated and their physiological role is unknown. Cocaine increases the level of dopamine, a key neurotransmitter in CNS motor control and reward areas. While the drug also affects dopaminergic signaling by allosteric modulations exerted by σ1R interacting with dopamine D1 and D2 receptors, the potential regulation of dopaminergic transmission by σ2R is also unknown. We here demonstrate that σ2R may form heteroreceptor complexes with D1 but not with D2 receptors. Remarkably σ1, σ2, and D1 receptors may form heterotrimers with particular signaling properties. Determination of cAMP levels, MAP kinase activation and label-free assays demonstrate allosteric interactions within the trimer. Importantly, the presence of σ2R induces bias in signal transduction as σ2R ligands increase cAMP signaling whereas reduce MAP kinase activation. These effects, which are opposite to those exerted via σ1R, suggest that the D1 receptor-mediated signaling depends on the degree of trimer formation and the differential balance of sigma receptor and heteroreceptor expression in acute versus chronic cocaine consumption. Although the physiological role is unknown, the heteroreceptor complex formed by σ1, σ2, and D1 receptors arise as relevant to convey the cocaine actions on motor control and reward circuits and as a key factor in acquisition of the addictive habit.

  20. Energy balance of algal biomass production in a 1-ha “Green Wall Panel” plant: How to produce algal biomass in a closed reactor achieving a high Net Energy Ratio

    International Nuclear Information System (INIS)

    Tredici, M.R.; Bassi, N.; Prussi, M.; Biondi, N.; Rodolfi, L.; Chini Zittelli, G.; Sampietro, G.

    2015-01-01

    Highlights: • Tetraselmis suecica production in a 1-ha GWP plant in Tuscany (Italy) has a NER < 1. • Major energy costs are embodied energy of GWP and mixing. • In a suitable location (North Africa) the NER increases by 40%. • Integration of photovoltaic in the GWP allows to achieve a NER of 1.7. • T. suecica cultivated in a GWP plant can yield up to 30 t of protein ha −1 year −1 . - Abstract: The annual productivity of Tetraselmis suecica in a 1-ha Green Wall Panel-II (GWP-II) plant in Tuscany (Italy) is 36 t (dry weight) ha −1 year −1 , which corresponds to an energy output of 799 GJ ha −1 year −1 . The energy inputs necessary to attain that productivity amount to 1362 GJ ha −1 year −1 , mainly given by the embodied energy of the reactor (about 30%), mixing (about 40%), fertilizers (11%) and harvesting (10%). The Net Energy Ratio (NER) of T. suecica production is thus 0.6. In a more suitable location (North Africa) productivity nearly doubles, reaching 66 t ha −1 year −1 , but the NER increases only by 40% and the gain (difference between output and inputs) remains negative. In a GWP-II integrated with photovoltaics (PV), the NER becomes 1.7 and the gain surpasses 600 GJ ha −1 year −1 . Marine microalgae cultivation in a GWP plant, in a suitable location, can attain high biomass productivities and protein yields 30 times higher than those achievable with traditional crops (soya). When the GWP reactor is integrated with PV, the process attains a positive energy balance, which substantially enhances its sustainability

  1. Greater expression of TLR2, TLR4, and IL6 due to negative energy balance is associated with lower expression of HLA-DRA and HLA-A in bovine blood neutrophils after intramammary mastitis challenge with Streptococcus uberis

    DEFF Research Database (Denmark)

    Moyes, Kasey; Drackley, James K; Morin, Dawn E

    2010-01-01

    Our objectives were to compare gene expression profiles in blood polymorphonuclear cells (PMN) during a Streptococcus uberis intramammary challenge between lactating cows subjected to feed restriction to induce negative energy balance (NEB; n = 5) and cows fed ad libitum to maintain positive ener...

  2. Protein Restriction with Amino Acid-Balanced Diets Shrinks Circulating Pool Size of Amino Acid by Decreasing Expression of Specific Transporters in the Small Intestine.

    Directory of Open Access Journals (Sweden)

    Kai Qiu

    Full Text Available Dietary protein restriction is not only beneficial to health and longevity in humans, but also protects against air pollution and minimizes feeding cost in livestock production. However, its impact on amino acid (AA absorption and metabolism is not quite understood. Therefore, the study aimed to explore the effect of protein restriction on nitrogen balance, circulating AA pool size, and AA absorption using a pig model. In Exp.1, 72 gilts weighting 29.9 ± 1.5 kg were allocated to 1 of the 3 diets containing 14, 16, or 18% CP for a 28-d trial. Growth (n = 24, nitrogen balance (n = 6, and the expression of small intestinal AA and peptide transporters (n = 6 were evaluated. In Exp.2, 12 barrows weighting 22.7 ± 1.3 kg were surgically fitted with catheters in the portal and jejunal veins as well as the carotid artery and assigned to a diet containing 14 or 18% CP. A series of blood samples were collected before and after feeding for determining the pool size of circulating AA and AA absorption in the portal vein, respectively. Protein restriction did not sacrifice body weight gain and protein retention, since nitrogen digestibility was increased as dietary protein content reduced. However, the pool size of circulating AA except for lysine and threonine, and most AA flux through the portal vein were reduced in pigs fed the low protein diet. Meanwhile, the expression of peptide transporter 1 (PepT-1 was stimulated, but the expression of the neutral and cationic AA transporter systems was depressed. These results evidenced that protein restriction with essential AA-balanced diets, decreased AA absorption and reduced circulating AA pool size. Increased expression of small intestinal peptide transporter PepT-1 could not compensate for the depressed expression of jejunal AA transporters for AA absorption.

  3. Coloured Petri Nets

    DEFF Research Database (Denmark)

    Jensen, Kurt

    1987-01-01

    The author describes a Petri net model, called coloured Petri nets (CP-nets), by means of which it is possible to describe large systems without having to cope with unnecessary details. The author introduces CP-nets and provide a first impression of their modeling power and the suitability...

  4. Learning Visual Basic NET

    CERN Document Server

    Liberty, Jesse

    2009-01-01

    Learning Visual Basic .NET is a complete introduction to VB.NET and object-oriented programming. By using hundreds of examples, this book demonstrates how to develop various kinds of applications--including those that work with databases--and web services. Learning Visual Basic .NET will help you build a solid foundation in .NET.

  5. Effect of A One-Week Balanced Diet on Expression of Genes Related to Zinc Metabolism and Inflammation in Type 2 Diabetic Patients.

    Science.gov (United States)

    Lais, Lucia Leite; de Lima Vale, Sancha Helena; Xavier, Camila Alves; de Araujo Silva, Alfredo; Aydemir, Tolunay Beker; Cousins, Robert J

    2016-01-01

    To evaluate the effect of diet on metabolic control and zinc metabolism in patients with type 2 diabetes mellitus (T2DM). One-week balanced diet was provided to 10 Brazilians patients with T2DM. Nutritional assessment, laboratorial parameters and expression of zinc transporter and inflammatory genes in peripheral blood mononuclear cells (PBMC) were performed. Healthy non-diabetic subjects of the same demographic were recruited to provide baseline data. Diabetic patients had higher body mass index and greater fasting plasma glucose, plasma tumor necrosis factor α (TNFα) and plasma interleukin 6 (IL6) levels compared with healthy subjects. In addition, the expression of transporters 4 (ZnT4) mRNA was lower and IL6 mRNA was higher in PBMC of these diabetic patients than in healthy subject. One week after a balanced diet was provided, fasting plasma glucose decreased significantly as did TNFα, IL6 and Metallothionein 1 (MT1) mRNAs. No change was observed in zinc transporter expression in PBMC after the dietary intervention. A healthy eating pattern maintained for one week was able to improve metabolic control of diabetic patients by lowering fasting plasma glucose. This metabolic control may be related to down-regulation of zinc-related transcripts from PBMCs, as TNFα, IL6 and MT1 mRNA.

  6. De Novo Herpes Simplex Virus VP16 Expression Gates a Dynamic Programmatic Transition and Sets the Latent/Lytic Balance during Acute Infection in Trigeminal Ganglia.

    Science.gov (United States)

    Sawtell, Nancy M; Thompson, Richard L

    2016-09-01

    The life long relationship between herpes simplex virus and its host hinges on the ability of the virus to aggressively replicate in epithelial cells at the site of infection and transport into the nervous system through axons innervating the infection site. Interaction between the virus and the sensory neuron represents a pivot point where largely unknown mechanisms lead to a latent or a lytic infection in the neuron. Regulation at this pivot point is critical for balancing two objectives, efficient widespread seeding of the nervous system and host survival. By combining genetic and in vivo in approaches, our studies reveal that the balance between latent and lytic programs is a process occurring early in the trigeminal ganglion. Unexpectedly, activation of the latent program precedes entry into the lytic program by 12 -14hrs. Importantly, at the individual neuronal level, the lytic program begins as a transition out of this acute stage latent program and this escape from the default latent program is regulated by de novo VP16 expression. Our findings support a model in which regulated de novo VP16 expression in the neuron mediates entry into the lytic cycle during the earliest stages of virus infection in vivo. These findings support the hypothesis that the loose association of VP16 with the viral tegument combined with sensory axon length and transport mechanisms serve to limit arrival of virion associated VP16 into neuronal nuclei favoring latency. Further, our findings point to specialized features of the VP16 promoter that control the de novo expression of VP16 in neurons and this regulation is a key component in setting the balance between lytic and latent infections in the nervous system.

  7. Reconciling estimates of the contemporary North American carbon balance among terrestrial biosphere models, atmospheric inversions, and a new approach for estimating net ecosystem exchange from inventory-based data

    Science.gov (United States)

    Daniel J. Hayes; David P. Turner; Graham Stinson; A. David Mcguire; Yaxing Wei; Tristram O. West; Linda S. Heath; Bernardus Dejong; Brian G. McConkey; Richard A. Birdsey; Werner A. Kurz; Andrew R. Jacobson; Deborah N. Huntzinger; Yude Pan; W. Mac Post; Robert B. Cook

    2012-01-01

    We develop an approach for estimating net ecosystem exchange (NEE) using inventory-based information over North America (NA) for a recent 7-year period (ca. 2000-2006). The approach notably retains information on the spatial distribution of NEE, or the vertical exchange between land and atmosphere of all non-fossil fuel sources and sinks of CO2,...

  8. NASA Net Zero Energy Buildings Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Pless, S.; Scheib, J.; Torcellini, P.; Hendron, B.; Slovensky, M.

    2014-10-01

    In preparation for the time-phased net zero energy requirement for new federal buildings starting in 2020, set forth in Executive Order 13514, NASA requested that the National Renewable Energy Laboratory (NREL) to develop a roadmap for NASA's compliance. NASA detailed a Statement of Work that requested information on strategic, organizational, and tactical aspects of net zero energy buildings. In response, this document presents a high-level approach to net zero energy planning, design, construction, and operations, based on NREL's first-hand experience procuring net zero energy construction, and based on NREL and other industry research on net zero energy feasibility. The strategic approach to net zero energy starts with an interpretation of the executive order language relating to net zero energy. Specifically, this roadmap defines a net zero energy acquisition process as one that sets an aggressive energy use intensity goal for the building in project planning, meets the reduced demand goal through energy efficiency strategies and technologies, then adds renewable energy in a prioritized manner, using building-associated, emission- free sources first, to offset the annual energy use required at the building; the net zero energy process extends through the life of the building, requiring a balance of energy use and production in each calendar year.

  9. Net energy gain from DT fusion

    International Nuclear Information System (INIS)

    Buende, R.

    1985-01-01

    The net energy which can be gained from an energy raw material by means of a certain conversion system is deduced as the figure-of-merit which adequately characterizes the net energy balance of utilizing an energy source. This potential net energy gain is determined for DT fusion power plants. It is represented as a function of the degree of exploitation of the energy raw material lithium ore and is compared with the net energy which can be gained with LW and FBR power plants by exploiting uranium ore. The comparison clearly demonstrates the net energetic advantage of DT fusion. A sensitivity study shows that this holds even if the energy expenditure for constructing and operating is drastically increased

  10. Serotonin 5-HT2C receptor-independent expression of hypothalamic NOR1, a novel modulator of food intake and energy balance, in mice

    Energy Technology Data Exchange (ETDEWEB)

    Nonogaki, Katsunori, E-mail: knonogaki-tky@umin.ac.jp [Center of Excellence, Division of Molecular Metabolism and Diabetes, Tohoku University Graduate School of Medicine (Japan); Department of Lifestyle Medicine, Biomedical Engineering Center, Tohoku University (Japan); Kaji, Takao [Department of Lifestyle Medicine, Biomedical Engineering Center, Tohoku University (Japan); Ohba, Yukie; Sumii, Makiko [Center of Excellence, Division of Molecular Metabolism and Diabetes, Tohoku University Graduate School of Medicine (Japan); Wakameda, Mamoru; Tamari, Tomohiro [Charles River Laboratories Japan, Inc. (Japan)

    2009-08-21

    NOR1, Nur77 and Nurr1 are orphan nuclear receptors and members of the NR4A subfamily. Here, we report that the expression of hypothalamic NOR1 was remarkably decreased in mildly obese {beta}-endorphin-deficient mice and obese db/db mice with the leptin receptor mutation, compared with age-matched wild-type mice, whereas there were no genotypic differences in the expression of hypothalamic Nur77 or Nurr1 in these animals. The injection of NOR1 siRNA oligonucleotide into the third cerebral ventricle significantly suppressed food intake and body weight in mice. On the other hand, the decreases in hypothalamic NOR1 expression were not found in non-obese 5-HT2C receptor-deficient mice. Moreover, systemic administration of m-chlorophenylpiperazine (mCPP), a 5-HT2C/1B receptor agonist, had no effect on hypothalamic NOR1 expression, while suppressing food intake in {beta}-endorphin-deficient mice. These findings suggest that 5-HT2C receptor-independent proopiomelanocortin-derived peptides regulate the expression of hypothalamic NOR1, which is a novel modulator of feeding behavior and energy balance.

  11. Serotonin 5-HT2C receptor-independent expression of hypothalamic NOR1, a novel modulator of food intake and energy balance, in mice

    International Nuclear Information System (INIS)

    Nonogaki, Katsunori; Kaji, Takao; Ohba, Yukie; Sumii, Makiko; Wakameda, Mamoru; Tamari, Tomohiro

    2009-01-01

    NOR1, Nur77 and Nurr1 are orphan nuclear receptors and members of the NR4A subfamily. Here, we report that the expression of hypothalamic NOR1 was remarkably decreased in mildly obese β-endorphin-deficient mice and obese db/db mice with the leptin receptor mutation, compared with age-matched wild-type mice, whereas there were no genotypic differences in the expression of hypothalamic Nur77 or Nurr1 in these animals. The injection of NOR1 siRNA oligonucleotide into the third cerebral ventricle significantly suppressed food intake and body weight in mice. On the other hand, the decreases in hypothalamic NOR1 expression were not found in non-obese 5-HT2C receptor-deficient mice. Moreover, systemic administration of m-chlorophenylpiperazine (mCPP), a 5-HT2C/1B receptor agonist, had no effect on hypothalamic NOR1 expression, while suppressing food intake in β-endorphin-deficient mice. These findings suggest that 5-HT2C receptor-independent proopiomelanocortin-derived peptides regulate the expression of hypothalamic NOR1, which is a novel modulator of feeding behavior and energy balance.

  12. Australian Government Balance Sheet Management

    OpenAIRE

    Wilson Au-Yeung; Jason McDonald; Amanda Sayegh

    2006-01-01

    Since almost eliminating net debt, the Australian Government%u2019s attention has turned to the financing of broader balance sheet liabilities, such as public sector superannuation. Australia will be developing a significant financial asset portfolio in the %u2018Future Fund%u2019 to smooth the financing of expenses through time. This raises the significant policy question of how best to manage the government balance sheet to reduce risk. This paper provides a framework for optimal balance sh...

  13. Planning of nets

    International Nuclear Information System (INIS)

    Carberry, M

    1996-01-01

    The paper is about the planning of nets in areas of low density like it is the case of the rural areas. The author includes economic and technological aspects, planning of nets, demands and management among others

  14. Annotating Coloured Petri Nets

    DEFF Research Database (Denmark)

    Lindstrøm, Bo; Wells, Lisa Marie

    2002-01-01

    Coloured Petri nets (CP-nets) can be used for several fundamentally different purposes like functional analysis, performance analysis, and visualisation. To be able to use the corresponding tool extensions and libraries it is sometimes necessary to include extra auxiliary information in the CP......-net. An example of such auxiliary information is a counter which is associated with a token to be able to do performance analysis. Modifying colour sets and arc inscriptions in a CP-net to support a specific use may lead to creation of several slightly different CP-nets – only to support the different uses...... of the same basic CP-net. One solution to this problem is that the auxiliary information is not integrated into colour sets and arc inscriptions of a CP-net, but is kept separately. This makes it easy to disable this auxiliary information if a CP-net is to be used for another purpose. This paper proposes...

  15. bHLH-O proteins balance the self-renewal and differentiation of Drosophila neural stem cells by regulating Earmuff expression.

    Science.gov (United States)

    Li, Xiaosu; Chen, Rui; Zhu, Sijun

    2017-11-15

    Balancing self-renewal and differentiation of stem cells requires differential expression of self-renewing factors in two daughter cells generated from the asymmetric division of the stem cells. In Drosophila type II neural stem cell (or neuroblast, NB) lineages, the expression of the basic helix-loop-helix-Orange (bHLH-O) family proteins, including Deadpan (Dpn) and E(spl) proteins, is required for maintaining the self-renewal and identity of type II NBs, whereas the absence of these self-renewing factors is essential for the differentiation of intermediate neural progenitors (INPs) generated from type II NBs. Here, we demonstrate that Dpn maintains type II NBs by suppressing the expression of Earmuff (Erm). We provide evidence that Dpn and E(spl) proteins suppress Erm by directly binding to C-sites and N-boxes in the cis-regulatory region of erm. Conversely, the absence of bHLH-O proteins in INPs allows activation of erm and Erm-mediated maturation of INPs. Our results further suggest that Pointed P1 (PntP1) mediates the dedifferentiation of INPs resulting from the loss of Erm or overexpression of Dpn or E(spl) proteins. Taken together, these findings reveal mechanisms underlying the regulation of the maintenance of type II NBs and differentiation of INPs through the differential expression of bHLH-O family proteins. Copyright © 2017 Elsevier Inc. All rights reserved.

  16. Classic cadherin expressions balance postnatal neuronal positioning and dendrite dynamics to elaborate the specific cytoarchitecture of the mouse cortical area.

    Science.gov (United States)

    Egusa, Saki F; Inoue, Yukiko U; Asami, Junko; Terakawa, Youhei W; Hoshino, Mikio; Inoue, Takayoshi

    2016-04-01

    A unique feature of the mammalian cerebral cortex is in its tangential parcellation via anatomical and functional differences. However, the cellular and/or molecular machinery involved in cortical arealization remain largely unknown. Here we map expression profiles of classic cadherins in the postnatal mouse barrel field of the primary somatosensory area (S1BF) and generate a novel bacterial artificial chromosome transgenic (BAC-Tg) mouse line selectively illuminating nuclei of cadherin-6 (Cdh6)-expressing layer IV barrel neurons to confirm that tangential cellular assemblage of S1BF is established by postnatal day 5 (P5). When we electroporate the cadherins expressed in both barrel neurons and thalamo-cortical axon (TCA) terminals limited to the postnatal layer IV neurons, S1BF cytoarchitecture is disorganized with excess elongation of dendrites at P7. Upon delivery of dominant negative molecules for all classic cadherins, tangential cellular positioning and biased dendritic arborization of barrel neurons are significantly altered. These results underscore the value of classic cadherin-mediated sorting among neuronal cell bodies, dendrites and TCA terminals in postnatally elaborating the S1BF-specific tangential cytoarchitecture. Additionally, how the "protocortex" machinery affects classic cadherin expression profiles in the process of cortical arealization is examined and discussed. Copyright © 2015 Elsevier Ireland Ltd and the Japan Neuroscience Society. All rights reserved.

  17. Balance Problems

    Science.gov (United States)

    ... often, it could be a sign of a balance problem. Balance problems can make you feel unsteady. You may ... related injuries, such as a hip fracture. Some balance problems are due to problems in the inner ...

  18. The garlic allelochemical diallyl disulfide affects tomato root growth by influencing cell division, phytohormone balance and expansin gene expression

    Directory of Open Access Journals (Sweden)

    Fang Cheng

    2016-08-01

    Full Text Available Diallyl disulfide (DADS is a volatile organosulfur compound derived from garlic (Allium sativum L., and it is known as an allelochemical responsible for the strong allelopathic potential of garlic. The anticancer properties of DADS have been studied in experimental animals and various types of cancer cells, but to date, little is known about its mode of action as an allelochemical at the cytological level. The current research presents further studies on the effects of DADS on tomato (Solanum lycopersicum L. seed germination, root growth, mitotic index and cell size in root meristem, as well as the phytohormone levels and expression profile of auxin biosynthesis genes (FZYs, auxin transport genes (SlPINs and expansin genes (EXPs in tomato root. The results showed a biphasic, dose-dependent effect on tomato seed germination and root growth under different DADS concentrations. Lower concentrations (0.01-0.62 mM of DADS significantly promoted root growth, whereas higher levels (6.20-20.67 mM showed inhibitory effects. Cytological observations showed that the cell length of root meristem was increased and that the mitotic activity of meristematic cells in seedling root tips was enhanced at lower concentrations of DADS. In contrast, DADS at higher concentrations inhibited root growth by affecting both the length and division activity of meristematic cells. However, the cell width of the root meristem was not affected. Additionally, DADS increased the IAA and ZR contents of seedling roots in a dose-dependent manner. The influence on IAA content may be mediated by the up-regulation of FZYs and PINs. Further investigation into the underlying mechanism revealed that the expression levels of tomato EXPs were significantly affected by DADS. The expression levels of EXPB2 and beta-expansin precursor were increased after 3 d, and those of EXP1, EXPB3 and EXLB1 were increased after 5 d of DADS treatment (0.41 mM. This result suggests that tomato root growth

  19. CF2 represses Actin 88F gene expression and maintains filament balance during indirect flight muscle development in Drosophila.

    Directory of Open Access Journals (Sweden)

    Kathleen M Gajewski

    2010-05-01

    Full Text Available The zinc finger protein CF2 is a characterized activator of muscle structural genes in the body wall muscles of the Drosophila larva. To investigate the function of CF2 in the indirect flight muscle (IFM, we examined the phenotypes of flies bearing five homozygous viable mutations. The gross structure of the IFM was not affected, but the stronger hypomorphic alleles caused an increase of up to 1.5X in the diameter of the myofibrils. This size increase did not cause any disruption of the hexameric arrangement of thick and thin filaments. RT-PCR analysis revealed an increase in the transcription of several structural genes. Ectopic overexpression of CF2 in the developing IFM disrupts muscle formation. While our results indicate a role for CF2 as a direct negative regulator of the thin filament protein gene Actin 88F (Act88F, effects on levels of transcripts of myosin heavy chain (mhc appear to be indirect. This role is in direct contrast to that described in the larval muscles, where CF2 activates structural gene expression. The variation in myofibril phenotypes of CF2 mutants suggest the CF2 may have separate functions in fine-tuning expression of structural genes to insure proper filament stoichiometry, and monitoring and/or controlling the final myofibril size.

  20. 47 CFR 32.4100 - Net current deferred operating income taxes.

    Science.gov (United States)

    2010-10-01

    ... SERVICES UNIFORM SYSTEM OF ACCOUNTS FOR TELECOMMUNICATIONS COMPANIES Instructions for Balance Sheet Accounts § 32.4100 Net current deferred operating income taxes. (a) This account shall include the balance...

  1. Reconciling estimates of the contemporary North American carbon balance among terrestrial biosphere models, atmospheric inversions, and a new approach for estimating net ecosystem exchange from inventory-based data

    Science.gov (United States)

    Hayes, Daniel J.; Turner, David P.; Stinson, Graham; McGuire, A. David; Wei, Yaxing; West, Tristram O.; Heath, Linda S.; de Jong, Bernardus; McConkey, Brian G.; Birdsey, Richard A.; Kurz, Werner A.; Jacobson, Andrew R.; Huntzinger, Deborah N.; Pan, Yude; Post, W. Mac; Cook, Robert B.

    2012-01-01

    We develop an approach for estimating net ecosystem exchange (NEE) using inventory-based information over North America (NA) for a recent 7-year period (ca. 2000–2006). The approach notably retains information on the spatial distribution of NEE, or the vertical exchange between land and atmosphere of all non-fossil fuel sources and sinks of CO2, while accounting for lateral transfers of forest and crop products as well as their eventual emissions. The total NEE estimate of a -327 ± 252 TgC yr-1 sink for NA was driven primarily by CO2 uptake in the Forest Lands sector (-248 TgC yr-1), largely in the Northwest and Southeast regions of the US, and in the Crop Lands sector (-297 TgC yr-1), predominantly in the Midwest US states. These sinks are counteracted by the carbon source estimated for the Other Lands sector (+218 TgC yr-1), where much of the forest and crop products are assumed to be returned to the atmosphere (through livestock and human consumption). The ecosystems of Mexico are estimated to be a small net source (+18 TgC yr-1) due to land use change between 1993 and 2002. We compare these inventory-based estimates with results from a suite of terrestrial biosphere and atmospheric inversion models, where the mean continental-scale NEE estimate for each ensemble is -511 TgC yr-1 and -931 TgC yr-1, respectively. In the modeling approaches, all sectors, including Other Lands, were generally estimated to be a carbon sink, driven in part by assumed CO2 fertilization and/or lack of consideration of carbon sources from disturbances and product emissions. Additional fluxes not measured by the inventories, although highly uncertain, could add an additional -239 TgC yr-1 to the inventory-based NA sink estimate, thus suggesting some convergence with the modeling approaches.

  2. Quantum net dynamics

    International Nuclear Information System (INIS)

    Finkelstein, D.

    1989-01-01

    The quantum net unifies the basic principles of quantum theory and relativity in a quantum spacetime having no ultraviolet infinities, supporting the Dirac equation, and having the usual vacuum as a quantum condensation. A correspondence principle connects nets to Schwinger sources and further unifies the vertical structure of the theory, so that the functions of the many hierarchic levels of quantum field theory (predicate algebra, set theory, topology,hor-ellipsis, quantum dynamics) are served by one in quantum net dynamics

  3. Balance Problems

    Science.gov (United States)

    ... fully trust your sense of balance. Loss of balance also raises the risk of falls. This is a serious and even life-threatening ... 65. Balance disorders are serious because of the risk of falls. But occasionally balance problems may warn of another health condition, such ...

  4. Programming NET Web Services

    CERN Document Server

    Ferrara, Alex

    2007-01-01

    Web services are poised to become a key technology for a wide range of Internet-enabled applications, spanning everything from straight B2B systems to mobile devices and proprietary in-house software. While there are several tools and platforms that can be used for building web services, developers are finding a powerful tool in Microsoft's .NET Framework and Visual Studio .NET. Designed from scratch to support the development of web services, the .NET Framework simplifies the process--programmers find that tasks that took an hour using the SOAP Toolkit take just minutes. Programming .NET

  5. Game Coloured Petri Nets

    DEFF Research Database (Denmark)

    Westergaard, Michael

    2006-01-01

    This paper introduces the notion of game coloured Petri nets. This allows the modeler to explicitly model what parts of the model comprise the modeled system and what parts are the environment of the modeled system. We give the formal definition of game coloured Petri nets, a means of reachability...... analysis of this net class, and an application of game coloured Petri nets to automatically generate easy-to-understand visualizations of the model by exploiting the knowledge that some parts of the model are not interesting from a visualization perspective (i.e. they are part of the environment...

  6. Caught in the Net: Perineuronal Nets and Addiction

    Directory of Open Access Journals (Sweden)

    Megan Slaker

    2016-01-01

    Full Text Available Exposure to drugs of abuse induces plasticity in the brain and creates persistent drug-related memories. These changes in plasticity and persistent drug memories are believed to produce aberrant motivation and reinforcement contributing to addiction. Most studies have explored the effect drugs of abuse have on pre- and postsynaptic cells and astrocytes; however, more recently, attention has shifted to explore the effect these drugs have on the extracellular matrix (ECM. Within the ECM are unique structures arranged in a net-like manner, surrounding a subset of neurons called perineuronal nets (PNNs. This review focuses on drug-induced changes in PNNs, the molecules that regulate PNNs, and the expression of PNNs within brain circuitry mediating motivation, reward, and reinforcement as it pertains to addiction.

  7. Two-Step Load Balancing Scheme for Fairness Improvement in ...

    African Journals Online (AJOL)

    ABSTRACT: The problem of load imbalance in HetNets among wireless access technologies is addressed in this article. ... balancing could either mean balancing the transmit power or the radio ..... Weight for Multimedia Transmission.

  8. Annual Energy Balance Sheets 2003-2004

    International Nuclear Information System (INIS)

    2005-01-01

    During the year 2004 the supply of primary energy reached 657.6 TWh. That is an increased supply by 16 TWh compared with 2003, The electricity production in hydropower and wind power stations increased by 7 TWh, to 61 TWh during the year 2004. The electricity generated in nuclear power plants was 77.5 TWh, an increase by 10 TWh. During the year 2004 Sweden net exported 2.1 TWh electricity. But in year 2003 we net imported 12.8 TWh electricity. The energy use increased from 406 TWh to 409 TWh between year 2003 and year 2004. The use of coal and coke in manufacturing increased by 22 per cent, and the use of oil products in transport sector increased by 4 per cent. The energy balance sheets are based on data primary recorded in the balance sheets of energy sources, here expressed in a common energy unit, TJ. The production of derived energy is here recorded in a second flow-step comprising energy turnover in energy conversion and is also specified in complementary input-output tables for energy conversion industries

  9. Model and calculations for net infiltration

    International Nuclear Information System (INIS)

    Childs, S.W.; Long, A.

    1992-01-01

    In this paper a conceptual model for calculating net infiltration is developed and implemented. It incorporates the following important factors: viability of climate for the next 10,000 years, areal viability of net infiltration, and important soil/plant factors that affect the soil water budget of desert soils. Model results are expressed in terms of occurrence probabilities for time periods. In addition the variability of net infiltration is demonstrated both for change with time and differences among three soil/hydrologic units present at the site modeled

  10. Coloured Petri Nets

    DEFF Research Database (Denmark)

    Jensen, Kurt

    1991-01-01

    This paper describes how Coloured Petri Nets (CP-nets) have been developed — from being a promising theoretical model to being a full-fledged language for the design, specification, simulation, validation and implementation of large software systems (and other systems in which human beings and...

  11. Net zero water

    CSIR Research Space (South Africa)

    Lindeque, M

    2013-01-01

    Full Text Available the national grid. The unfortunate situation with water is that there is no replacement technology for water. Water can be supplied from many different sources. A net zero energy development will move closer to a net zero water development by reducing...

  12. Construction of monophase nets

    International Nuclear Information System (INIS)

    Suarez A, Jose Antonio

    1996-01-01

    The paper refers to the use of monophase loads in commercial residential urbanizations and in small industries, for this reason it is considered unnecessary the construction of three-phase nets. The author makes a historical recount of these nets in Bogota, his capacities, uses and energy savings

  13. Fusion through the NET

    International Nuclear Information System (INIS)

    Spears, B.

    1987-01-01

    The paper concerns the next generation of fusion machines which are intended to demonstrate the technical viability of fusion. In Europe, the device that will follow on from JET is known as NET - the Next European Torus. If the design programme for NET proceeds, Europe could start to build the machine in 1994. The present JET programme hopes to achieve breakeven in the early 1990's. NET hopes to reach ignition in the next century, and so lay the foundation for a demonstration reactor. A description is given of the technical specifications of the components of NET, including: the first wall, the divertors to protect the wall, the array of magnets that provide the fields containing the plasma, the superconducting magnets, and the shield of the machine. NET's research programme is briefly outlined, including the testing programme to optimise conditions in the machine to achieve ignition, and its safety work. (U.K.)

  14. 40 CFR 1065.290 - PM gravimetric balance.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false PM gravimetric balance. 1065.290... balance. (a) Application. Use a balance to weigh net PM on a sample medium for laboratory testing. (b) Component requirements. We recommend that you use a balance that meets the specifications in Table 1 of...

  15. Net community production in the northern Indian Ocean

    Digital Repository Service at National Institute of Oceanography (India)

    Sarma, V.V.S.S.

    . On the other hand, Sarma [2004, Net community production in the Bay of Bengal: Oxygen mass balance approach, submitted to Bio- geochemistry, 2008] computed NCP using a regional model of oxygen mass balance in the NIO. Bates et al. [2006] also estimated NCP... using an inorganic carbon mass balance model for the entire Indian Ocean. This chapter combines the results obtained from direct measurements and models and aims at improving our understanding of processes con­ trolling NCP in the NIO...

  16. Net Zero Energy Buildings

    DEFF Research Database (Denmark)

    Marszal, Anna Joanna; Bourrelle, Julien S.; Gustavsen, Arild

    2010-01-01

    and identify possible renewable energy supply options which may be considered in calculations. Finally, the gap between the methodology proposed by each organisation and their respective national building code is assessed; providing an overview of the possible changes building codes will need to undergo......The international cooperation project IEA SHC Task 40 / ECBCS Annex 52 “Towards Net Zero Energy Solar Buildings”, attempts to develop a common understanding and to set up the basis for an international definition framework of Net Zero Energy Buildings (Net ZEBs). The understanding of such buildings...

  17. Getting to Net Zero

    Energy Technology Data Exchange (ETDEWEB)

    2016-09-01

    The technology necessary to build net zero energy buildings (NZEBs) is ready and available today, however, building to net zero energy performance levels can be challenging. Energy efficiency measures, onsite energy generation resources, load matching and grid interaction, climatic factors, and local policies vary from location to location and require unique methods of constructing NZEBs. It is recommended that Components start looking into how to construct and operate NZEBs now as there is a learning curve to net zero construction and FY 2020 is just around the corner.

  18. Pro NET Best Practices

    CERN Document Server

    Ritchie, Stephen D

    2011-01-01

    Pro .NET Best Practices is a practical reference to the best practices that you can apply to your .NET projects today. You will learn standards, techniques, and conventions that are sharply focused, realistic and helpful for achieving results, steering clear of unproven, idealistic, and impractical recommendations. Pro .NET Best Practices covers a broad range of practices and principles that development experts agree are the right ways to develop software, which includes continuous integration, automated testing, automated deployment, and code analysis. Whether the solution is from a free and

  19. Net accumulation of the Greenland ice sheet

    DEFF Research Database (Denmark)

    Kiilsholm, Sissi; Christensen, Jens Hesselbjerg; Dethloff, Klaus

    2003-01-01

    High-resolution (50 km) climate change simulations for an area covering the entire Arctic have been conducted with the regional climate model (RCM) HIRHAM. The experiments were forced at the lateral boundary by large-scale atmospheric conditions from transient climate change scenario simulations...... with HIRHAM for periods representing present-day (1961-1990) and the future (2071-2100) in the two scenarios. We find that due to a much better representation of the surface topography in the RCM, the geographical distribution of present-day accumulation rates simulated by the RCM represents a substantial...... improvement compared to the driving OAGCM. Estimates of the regional net balance are also better represented by the RCM. In the future climate the net balance for the Greenland Ice Sheet is reduced in all the simulation, but discrepancies between the amounts when based on ECHAM4/OPYC3 and HIRHAM are found...

  20. Optimization of CDT-1 and XYL1 Expression for Balanced Co-Production of Ethanol and Xylitol from Cellobiose and Xylose by Engineered Saccharomyces cerevisiae

    Science.gov (United States)

    Zha, Jian; Li, Bing-Zhi; Shen, Ming-Hua; Hu, Meng-Long; Song, Hao; Yuan, Ying-Jin

    2013-01-01

    Production of ethanol and xylitol from lignocellulosic hydrolysates is an alternative to the traditional production of ethanol in utilizing biomass. However, the conversion efficiency of xylose to xylitol is restricted by glucose repression, causing a low xylitol titer. To this end, we cloned genes CDT-1 (encoding a cellodextrin transporter) and gh1-1 (encoding an intracellular β-glucosidase) from Neurospora crassa and XYL1 (encoding a xylose reductase that converts xylose into xylitol) from Scheffersomyces stipitis into Saccharomyces cerevisiae, enabling simultaneous production of ethanol and xylitol from a mixture of cellobiose and xylose (main components of lignocellulosic hydrolysates). We further optimized the expression levels of CDT-1 and XYL1 by manipulating their promoters and copy-numbers, and constructed an engineered S. cerevisiae strain (carrying one copy of PGK1p-CDT1 and two copies of TDH3p-XYL1), which showed an 85.7% increase in xylitol production from the mixture of cellobiose and xylose than that from the mixture of glucose and xylose. Thus, we achieved a balanced co-fermentation of cellobiose (0.165 g/L/h) and xylose (0.162 g/L/h) at similar rates to co-produce ethanol (0.36 g/g) and xylitol (1.00 g/g). PMID:23844185

  1. Optimization of CDT-1 and XYL1 expression for balanced co-production of ethanol and xylitol from cellobiose and xylose by engineered Saccharomyces cerevisiae.

    Directory of Open Access Journals (Sweden)

    Jian Zha

    Full Text Available Production of ethanol and xylitol from lignocellulosic hydrolysates is an alternative to the traditional production of ethanol in utilizing biomass. However, the conversion efficiency of xylose to xylitol is restricted by glucose repression, causing a low xylitol titer. To this end, we cloned genes CDT-1 (encoding a cellodextrin transporter and gh1-1 (encoding an intracellular β-glucosidase from Neurospora crassa and XYL1 (encoding a xylose reductase that converts xylose into xylitol from Scheffersomyces stipitis into Saccharomyces cerevisiae, enabling simultaneous production of ethanol and xylitol from a mixture of cellobiose and xylose (main components of lignocellulosic hydrolysates. We further optimized the expression levels of CDT-1 and XYL1 by manipulating their promoters and copy-numbers, and constructed an engineered S. cerevisiae strain (carrying one copy of PGK1p-CDT1 and two copies of TDH3p-XYL1, which showed an 85.7% increase in xylitol production from the mixture of cellobiose and xylose than that from the mixture of glucose and xylose. Thus, we achieved a balanced co-fermentation of cellobiose (0.165 g/L/h and xylose (0.162 g/L/h at similar rates to co-produce ethanol (0.36 g/g and xylitol (1.00 g/g.

  2. The Consolidated Net Worth of Private Colleges. Recommendation of a Model.

    Science.gov (United States)

    Jenny, Hans H.

    One of several essential tools for assessing how the financial health of educational institutions is evolving is the Consolidated Net Worth Statement. This essay explores various aspects of conventional "funds" balance sheets and compares them with the Consolidated Net Worth. Emphasis is placed on how the Consolidated Net Worth Statement…

  3. PhysioNet

    Data.gov (United States)

    U.S. Department of Health & Human Services — The PhysioNet Resource is intended to stimulate current research and new investigations in the study of complex biomedical and physiologic signals. It offers free...

  4. NetSig

    DEFF Research Database (Denmark)

    Horn, Heiko; Lawrence, Michael S; Chouinard, Candace R

    2018-01-01

    Methods that integrate molecular network information and tumor genome data could complement gene-based statistical tests to identify likely new cancer genes; but such approaches are challenging to validate at scale, and their predictive value remains unclear. We developed a robust statistic (Net......Sig) that integrates protein interaction networks with data from 4,742 tumor exomes. NetSig can accurately classify known driver genes in 60% of tested tumor types and predicts 62 new driver candidates. Using a quantitative experimental framework to determine in vivo tumorigenic potential in mice, we found that Net......Sig candidates induce tumors at rates that are comparable to those of known oncogenes and are ten-fold higher than those of random genes. By reanalyzing nine tumor-inducing NetSig candidates in 242 patients with oncogene-negative lung adenocarcinomas, we find that two (AKT2 and TFDP2) are significantly amplified...

  5. Blanket testing in NET

    International Nuclear Information System (INIS)

    Chazalon, M.; Daenner, W.; Libin, B.

    1989-01-01

    The testing stages in NET for the performance assessment of the various breeding blanket concepts developed at the present time in Europe for DEMO (LiPb and ceramic blankets) and the requirements upon NET to perform these tests are reviewed. Typical locations available in NET for blanket testing are the central outboard segments and the horizontal ports of in-vessel sectors. These test positions will be connectable with external test loops. The number of test loops (helium, water, liquid metal) will be such that each major class of blankets can be tested in NET. The test positions, the boundary conditions and the external test loops are identified and the requirements for test blankets are summarized (author). 6

  6. Programming NET 35

    CERN Document Server

    Liberty, Jesse

    2009-01-01

    Bestselling author Jesse Liberty and industry expert Alex Horovitz uncover the common threads that unite the .NET 3.5 technologies, so you can benefit from the best practices and architectural patterns baked into the new Microsoft frameworks. The book offers a Grand Tour" of .NET 3.5 that describes how the principal technologies can be used together, with Ajax, to build modern n-tier and service-oriented applications. "

  7. NET SALARY ADJUSTMENT

    CERN Multimedia

    Finance Division

    2001-01-01

    On 15 June 2001 the Council approved the correction of the discrepancy identified in the net salary adjustment implemented on 1st January 2001 by retroactively increasing the scale of basic salaries to achieve the 2.8% average net salary adjustment approved in December 2000. We should like to inform you that the corresponding adjustment will be made to your July salary. Full details of the retroactive adjustments will consequently be shown on your pay slip.

  8. Investigations of a Cost-Optimal Zero Energy Balance

    DEFF Research Database (Denmark)

    Marszal, Anna Joanna; Nørgaard, Jesper; Heiselberg, Per

    2012-01-01

    The Net Zero Energy Building (Net ZEB) concept is worldwide recognised as a promising solution for decreasing buildings’ energy use. Nevertheless, a consistent definition of the Net ZEB concept is constantly under discussion. One of the points on the Net ZEB agenda is the zero energy balance...... and taken a view point of private building owner to investigate what types of energy uses should be included in the cost-optimal zero energy balance. The analysis is conducted for five renewable energy supply systems and five user profiles with a study case of a multi-storey residential Net ZEB. The results...... have indicated that with current energy prices and technology, a cost-optimal Net ZEB zero energy balance accounts for only the building related energy use. Moreover, with high user related energy use is even more in favour of excluding appliances from the zero energy balance....

  9. Expression

    Directory of Open Access Journals (Sweden)

    Wang-Xia Wang

    2014-02-01

    Full Text Available The miR-15/107 family comprises a group of 10 paralogous microRNAs (miRNAs, sharing a 5′ AGCAGC sequence. These miRNAs have overlapping targets. In order to characterize the expression of miR-15/107 family miRNAs, we employed customized TaqMan Low-Density micro-fluid PCR-array to investigate the expression of miR-15/107 family members, and other selected miRNAs, in 11 human tissues obtained at autopsy including the cerebral cortex, frontal cortex, primary visual cortex, thalamus, heart, lung, liver, kidney, spleen, stomach and skeletal muscle. miR-103, miR-195 and miR-497 were expressed at similar levels across various tissues, whereas miR-107 is enriched in brain samples. We also examined the expression patterns of evolutionarily conserved miR-15/107 miRNAs in three distinct primary rat brain cell preparations (enriched for cortical neurons, astrocytes and microglia, respectively. In primary cultures of rat brain cells, several members of the miR-15/107 family are enriched in neurons compared to other cell types in the central nervous system (CNS. In addition to mature miRNAs, we also examined the expression of precursors (pri-miRNAs. Our data suggested a generally poor correlation between the expression of mature miRNAs and their precursors. In summary, we provide a detailed study of the tissue and cell type-specific expression profile of this highly expressed and phylogenetically conserved family of miRNA genes.

  10. Net alkalinity and net acidity 1: Theoretical considerations

    International Nuclear Information System (INIS)

    Kirby, Carl S.; Cravotta, Charles A.

    2005-01-01

    Net acidity and net alkalinity are widely used, poorly defined, and commonly misunderstood parameters for the characterization of mine drainage. The authors explain theoretical expressions of 3 types of alkalinity (caustic, phenolphthalein, and total) and acidity (mineral, CO 2 , and total). Except for rarely-invoked negative alkalinity, theoretically defined total alkalinity is closely analogous to measured alkalinity and presents few practical interpretation problems. Theoretically defined 'CO 2 -acidity' is closely related to most standard titration methods with an endpoint pH of 8.3 used for determining acidity in mine drainage, but it is unfortunately named because CO 2 is intentionally driven off during titration of mine-drainage samples. Using the proton condition/mass-action approach and employing graphs to illustrate speciation with changes in pH, the authors explore the concept of principal components and how to assign acidity contributions to aqueous species commonly present in mine drainage. Acidity is defined in mine drainage based on aqueous speciation at the sample pH and on the capacity of these species to undergo hydrolysis to pH 8.3. Application of this definition shows that the computed acidity in mgL -1 as CaCO 3 (based on pH and analytical concentrations of dissolved Fe II , Fe III , Mn, and Al in mgL -1 ):acidity calculated =50{1000(10 -pH )+[2(Fe II )+3(Fe III )]/56+2(Mn) /55+3(Al)/27}underestimates contributions from HSO 4 - and H + , but overestimates the acidity due to Fe 3+ and Al 3+ . However, these errors tend to approximately cancel each other. It is demonstrated that 'net alkalinity' is a valid mathematical construction based on theoretical definitions of alkalinity and acidity. Further, it is shown that, for most mine-drainage solutions, a useful net alkalinity value can be derived from: (1) alkalinity and acidity values based on aqueous speciation (2) measured alkalinity minus calculated acidity, or (3) taking the negative of the

  11. Net alkalinity and net acidity 1: Theoretical considerations

    Science.gov (United States)

    Kirby, C.S.; Cravotta, C.A.

    2005-01-01

    Net acidity and net alkalinity are widely used, poorly defined, and commonly misunderstood parameters for the characterization of mine drainage. The authors explain theoretical expressions of 3 types of alkalinity (caustic, phenolphthalein, and total) and acidity (mineral, CO2, and total). Except for rarely-invoked negative alkalinity, theoretically defined total alkalinity is closely analogous to measured alkalinity and presents few practical interpretation problems. Theoretically defined "CO 2-acidity" is closely related to most standard titration methods with an endpoint pH of 8.3 used for determining acidity in mine drainage, but it is unfortunately named because CO2 is intentionally driven off during titration of mine-drainage samples. Using the proton condition/mass- action approach and employing graphs to illustrate speciation with changes in pH, the authors explore the concept of principal components and how to assign acidity contributions to aqueous species commonly present in mine drainage. Acidity is defined in mine drainage based on aqueous speciation at the sample pH and on the capacity of these species to undergo hydrolysis to pH 8.3. Application of this definition shows that the computed acidity in mg L -1 as CaCO3 (based on pH and analytical concentrations of dissolved FeII, FeIII, Mn, and Al in mg L -1):aciditycalculated=50{1000(10-pH)+[2(FeII)+3(FeIII)]/56+2(Mn)/ 55+3(Al)/27}underestimates contributions from HSO4- and H+, but overestimates the acidity due to Fe3+ and Al3+. However, these errors tend to approximately cancel each other. It is demonstrated that "net alkalinity" is a valid mathematical construction based on theoretical definitions of alkalinity and acidity. Further, it is shown that, for most mine-drainage solutions, a useful net alkalinity value can be derived from: (1) alkalinity and acidity values based on aqueous speciation, (2) measured alkalinity minus calculated acidity, or (3) taking the negative of the value obtained in a

  12. Global reinforcement training of CrossNets

    Science.gov (United States)

    Ma, Xiaolong

    2007-10-01

    Hybrid "CMOL" integrated circuits, incorporating advanced CMOS devices for neural cell bodies, nanowires as axons and dendrites, and latching switches as synapses, may be used for the hardware implementation of extremely dense (107 cells and 1012 synapses per cm2) neuromorphic networks, operating up to 10 6 times faster than their biological prototypes. We are exploring several "Cross- Net" architectures that accommodate the limitations imposed by CMOL hardware and should allow effective training of the networks without a direct external access to individual synapses. Our studies have show that CrossNets based on simple (two-terminal) crosspoint devices can work well in at least two modes: as Hop-field networks for associative memory and multilayer perceptrons for classification tasks. For more intelligent tasks (such as robot motion control or complex games), which do not have "examples" for supervised learning, more advanced training methods such as the global reinforcement learning are necessary. For application of global reinforcement training algorithms to CrossNets, we have extended Williams's REINFORCE learning principle to a more general framework and derived several learning rules that are more suitable for CrossNet hardware implementation. The results of numerical experiments have shown that these new learning rules can work well for both classification tasks and reinforcement tasks such as the cartpole balancing control problem. Some limitations imposed by the CMOL hardware need to be carefully addressed for the the successful application of in situ reinforcement training to CrossNets.

  13. Balancing Audio

    DEFF Research Database (Denmark)

    Walther-Hansen, Mads

    2016-01-01

    is not thoroughly understood. In this paper I treat balance as a metaphor that we use to reason about several different actions in music production, such as adjusting levels, editing the frequency spectrum or the spatiality of the recording. This study is based on an exploration of a linguistic corpus of sound......This paper explores the concept of balance in music production and examines the role of conceptual metaphors in reasoning about audio editing. Balance may be the most central concept in record production, however, the way we cognitively understand and respond meaningfully to a mix requiring balance...

  14. Trade-Offs Associated with Photoprotective Green Fluorescent Protein Expression as Potential Drivers of Balancing Selection for Color Polymorphism in Reef Corals

    Directory of Open Access Journals (Sweden)

    Cathryn Quick

    2018-02-01

    Full Text Available Photodamage of symbiotic algae exposed to thermal stress is involved in mass coral bleaching, a major cause of reef decline. Photoprotection is therefore a vital part of coral stress physiology. Corals produce a variety of green fluorescent protein (GFP-like proteins, some of which screen the symbiotic algae from excess sun light. Different tissue concentrations of these GFP-like proteins distinguish color morphs that are characteristic for many coral species. The question arises whether these pigmentation differences may diversify the niches that can be occupied by corals along the steep light gradient that structures coral reef communities. We assessed the implications of GFP-like protein expression in two color morphs of the symbiotic coral Hydnophora grandis, both associated with the same Symbiodinium sp. (subclade C40. The color morphs of this species (high fluorescent, HF; and low fluorescent, LF, characterized by markedly different contents of a cyan fluorescent protein, were exposed to different quantities of blue light (470 nm that matched the major absorption band of the host pigment (473 nm. High intensities of blue light caused less photodamage to the symbiotic algae of the HF morph and resulted in higher growth rates of these corals compared to representatives of the LF morph. In contrast, under low intensities of blue light, the HF morph showed lower growth rates than the LF morph, indicating that trade-offs are associated with high levels of fluorescent protein expression under this condition. Both morphs showed highest growth rates at medium light intensities with no obvious influence of the tissue pigmentation. Reef coral color polymorphism caused by photoprotective GFP-like proteins may therefore be a product of balancing selection in which high pigment contents may be beneficial at the upper and detrimental at the lower end of the depth distribution range of symbiotic corals. Conversely, color morphs with GFP-like proteins

  15. Petri Nets as Models of Linear Logic

    DEFF Research Database (Denmark)

    Engberg, Uffe Henrik; Winskel, Glynn

    1990-01-01

    The chief purpose of this paper is to appraise the feasibility of Girad's linear logic as a specification language for parallel processes. To this end we propose an interpretation of linear logic in Petri nets, with respect to which we investigate the expressive power of the logic...

  16. Biological Petri Nets

    CERN Document Server

    Wingender, E

    2011-01-01

    It was suggested some years ago that Petri nets might be well suited to modeling metabolic networks, overcoming some of the limitations encountered by the use of systems employing ODEs (ordinary differential equations). Much work has been done since then which confirms this and demonstrates the usefulness of this concept for systems biology. Petri net technology is not only intuitively understood by scientists trained in the life sciences, it also has a robust mathematical foundation and provides the required degree of flexibility. As a result it appears to be a very promising approach to mode

  17. Reconfiguration of distribution nets

    International Nuclear Information System (INIS)

    Latorre Bayona, Gerardo; Angarita Marquez, Jorge Luis

    2000-01-01

    Starting of the location of the reconfiguration problem inside the context of the operation of distribution nets, of the quality indicators definition and of the presentation of the alternatives more used for reduction of technical losses, they are related diverse reconfiguration methodologies proposed in the technical literature, pointing out their three principals limitations; also are presents the results of lost obtained starting from simulation works carried out in distribution circuits of the ESSA ESP, which permitting to postulate the reconfiguration of nets like an excellent alternative to reduce technical losses

  18. NET system integration

    International Nuclear Information System (INIS)

    Farfaletti-Casali, F.; Mitchell, N.; Salpietro, E.; Buzzi, U.; Gritzmann, P.

    1985-01-01

    The NET system integration procedure is the process by which the requirements of the various Tokamak machine design areas are brought together to form a compatible machine layout. Each design area produces requirements which generally allow components to be built at minimum cost and operate with minimum technical risk, and the final machine assembly should be achieved with minimum departure from these optimum designs. This is carried out in NET by allowing flexibility in the maintenance and access methods to the machine internal components which must be regularly replaced by remote handling, in segmentation of these internal components and in the number of toroidal field coils

  19. Balancing Act

    Science.gov (United States)

    Part of being an Active, More Powerful You means finding balance in your daily life: taking on the Must-dos and finding time for some Should Dos and Want-to-Dos. Sometimes, emotions and commitments can come into play and upset the balance.

  20. Balanced sampling

    NARCIS (Netherlands)

    Brus, D.J.

    2015-01-01

    In balanced sampling a linear relation between the soil property of interest and one or more covariates with known means is exploited in selecting the sampling locations. Recent developments make this sampling design attractive for statistical soil surveys. This paper introduces balanced sampling

  1. Coloured Petri Nets

    CERN Document Server

    Jensen, Kurt

    2009-01-01

    Coloured Petri Nets (CPN) is a graphical language for modelling and validating concurrent and distributed systems, and other systems in which concurrency plays a major role. This book introduces the constructs of the CPN modelling language and presents the related analysis methods. It provides a comprehensive road map for the practical use of CPN.

  2. Safety nets or straitjackets?

    DEFF Research Database (Denmark)

    Ilsøe, Anna

    2012-01-01

    Does regulation of working hours at national and sector level impose straitjackets, or offer safety nets to employees seeking working time flexibility? This article compares legislation and collective agreements in the metal industries of Denmark, Germany and the USA. The industry has historically...

  3. Neuronal nets in robotics

    International Nuclear Information System (INIS)

    Jimenez Sanchez, Raul

    1999-01-01

    The paper gives a generic idea of the solutions that the neuronal nets contribute to the robotics. The advantages and the inconveniences are exposed that have regarding the conventional techniques. It also describe the more excellent applications as the pursuit of trajectories, the positioning based on images, the force control or of the mobile robots management, among others

  4. Net4Care platform

    DEFF Research Database (Denmark)

    2012-01-01

    , that in turn enables general practitioners and clinical staff to view observations. Use the menus above to explore the site's information resources. To get started, follow the short Hello, World! tutorial. The Net4Care project is funded by The Central Denmark Region and EU via Caretech Innovation....

  5. Coloured Petri Nets

    DEFF Research Database (Denmark)

    Jensen, Kurt; Kristensen, Lars Michael

    Coloured Petri Nets (CPN) is a graphical language for modelling and validating concurrent and distributed systems, and other systems in which concurrency plays a major role. The development of such systems is particularly challenging because of inherent intricacies like possible nondeterminism an...

  6. Game Theory .net.

    Science.gov (United States)

    Shor, Mikhael

    2003-01-01

    States making game theory relevant and accessible to students is challenging. Describes the primary goal of GameTheory.net is to provide interactive teaching tools. Indicates the site strives to unite educators from economics, political and computer science, and ecology by providing a repository of lecture notes and tests for courses using…

  7. BacillusRegNet

    DEFF Research Database (Denmark)

    Misirli, Goksel; Hallinan, Jennifer; Röttger, Richard

    2014-01-01

    As high-throughput technologies become cheaper and easier to use, raw sequence data and corresponding annotations for many organisms are becoming available. However, sequence data alone is not sufficient to explain the biological behaviour of organisms, which arises largely from complex molecular...... the associated BacillusRegNet website (http://bacillus.ncl.ac.uk)....

  8. Boom Booom Net Radio

    DEFF Research Database (Denmark)

    Grimshaw, Mark Nicholas; Yong, Louisa; Dobie, Ian

    1999-01-01

    of an existing Internet radio station; Boom Booom Net Radio. Whilst necessity dictates some use of technology-related terminology, wherever possible we have endeavoured to keep such jargon to a minimum and to either explain it in the text or to provide further explanation in the appended glossary....

  9. Global patterns in human consumption of net primary production

    Science.gov (United States)

    Imhoff, Marc L.; Bounoua, Lahouari; Ricketts, Taylor; Loucks, Colby; Harriss, Robert; Lawrence, William T.

    2004-06-01

    The human population and its consumption profoundly affect the Earth's ecosystems. A particularly compelling measure of humanity's cumulative impact is the fraction of the planet's net primary production that we appropriate for our own use. Net primary production-the net amount of solar energy converted to plant organic matter through photosynthesis-can be measured in units of elemental carbon and represents the primary food energy source for the world's ecosystems. Human appropriation of net primary production, apart from leaving less for other species to use, alters the composition of the atmosphere, levels of biodiversity, energy flows within food webs and the provision of important ecosystem services. Here we present a global map showing the amount of net primary production required by humans and compare it to the total amount generated on the landscape. We then derive a spatial balance sheet of net primary production `supply' and `demand' for the world. We show that human appropriation of net primary production varies spatially from almost zero to many times the local primary production. These analyses reveal the uneven footprint of human consumption and related environmental impacts, indicate the degree to which human populations depend on net primary production `imports' and suggest policy options for slowing future growth of human appropriation of net primary production.

  10. EXPRESS

    International Nuclear Information System (INIS)

    Ancelin, C.; Le, P.; DeSaint-Quentin, S.; Villatte, N.

    1987-01-01

    This paper presents EXPRESS, an expert system developed for the automation of reliability studies. The first part consists in the description of the method for static thermohydraulic systems. In this step, the authors define the knowledge representation based on the two inference engines - ALOUETTE and LCR developed by EDF. They explain all the process to construct a fault tree from a topological and functional description of the system. Numerous examples are exhibited in illustration of the method. This is followed by the lessons derived from the studies performed on some safety systems of the PALUEL nuclear plant. The development of the same approach for electric power systems is described, insisting on the difference resulting from the sequential nature of these systems. Finally, they show the main advantages identified during the studies

  11. SolNet

    DEFF Research Database (Denmark)

    Jordan, Ulrike; Vajen, Klaus; Bales, Chris

    2014-01-01

    -accompanying Master courses, placements of internships, and PhD scholarship projects. A new scholarship project, “SHINE”, was launched in autumn 2013 in the frame work of the Marie Curie program of the European Union (Initial Training Network, ITN). 13 PhD-scholarships on solar district heating, solar heat......SolNet, founded in 2006, is the first coordinated International PhD education program on Solar Thermal Engineering. The SolNet network is coordinated by the Institute of Thermal Engineering at Kassel University, Germany. The network offers PhD courses on solar heating and cooling, conference...... for industrial processes, as well as sorption stores and materials started in December 2013. Additionally, the project comprises a training program with five PhD courses and several workshops on solar thermal engineering that will be open also for other PhD students working in the field. The research projects...

  12. Turkey's net energy consumption

    International Nuclear Information System (INIS)

    Soezen, Adnan; Arcaklioglu, Erol; Oezkaymak, Mehmet

    2005-01-01

    The main goal of this study is to develop the equations for forecasting net energy consumption (NEC) using an artificial neural-network (ANN) technique in order to determine the future level of energy consumption in Turkey. In this study, two different models were used in order to train the neural network. In one of them, population, gross generation, installed capacity and years are used in the input layer of the network (Model 1). Other energy sources are used in input layer of network (Model 2). The net energy consumption is in the output layer for two models. Data from 1975 to 2003 are used for the training. Three years (1981, 1994 and 2003) are used only as test data to confirm this method. The statistical coefficients of multiple determinations (R 2 -value) for training data are equal to 0.99944 and 0.99913 for Models 1 and 2, respectively. Similarly, R 2 values for testing data are equal to 0.997386 and 0.999558 for Models 1 and 2, respectively. According to the results, the net energy consumption using the ANN technique has been predicted with acceptable accuracy. Apart from reducing the whole time required, with the ANN approach, it is possible to find solutions that make energy applications more viable and thus more attractive to potential users. It is also expected that this study will be helpful in developing highly applicable energy policies

  13. Activation of PAD4 in NET formation

    Directory of Open Access Journals (Sweden)

    Amanda eRohrbach

    2012-11-01

    Full Text Available Peptidyl arginine deiminases, or PADs, convert arginine residues to the non-ribosomally encoded amino acid citrulline in a variety of protein substrates. PAD4 is expressed in granulocytes and is essential for the formation of neutrophil extracellular traps (NETs via PAD4-mediated histone citrullination. Citrullination of histones is thought to promote NET formation by inducing chromatin decondensation and facilitating the expulsion of chromosomal DNA that is coated with antimicrobial molecules. Numerous stimuli have been reported to lead to PAD4 activation and NET formation. However, how this signaling process proceeds and how PAD4 becomes activated in cells is largely unknown. Herein, we describe the various stimuli and signaling pathways that have been implicated in PAD4 activation and NET formation, including the role of reactive oxygen species generation. To provide a foundation for the above discussion, we first describe PAD4 structure and function, and how these studies led to the development of PAD-specific inhibitors. A comprehensive survey of the receptors and signaling pathways that regulate PAD4 activation will be important for our understanding of innate immunity, and the identification of signaling intermediates in PAD4 activation may also lead to the generation of pharmaceuticals to target NET-related pathogenesis.

  14. Analysis of solar radiation transfer: A method to estimate the porosity of a plastic shading net

    International Nuclear Information System (INIS)

    Abdel-Ghany, A.M.; Al-Helal, I.M.

    2011-01-01

    Plastic nets with opaque threads are frequently used for shading agricultural structures under high solar radiation conditions. A parameter that is often used to define a net is the net porosity (Π). Value of Π is usually estimated by one of three methods: image processing, direct beam transmittance, or solar radiation balance (hereafter radiation balance). Image processing is a rather slow process because it requires scanning the net sample at high resolution. The direct beam transmittance and radiation balance methods greatly overestimate Π because some of the solar radiation incident on the thread surfaces is forward scattered and add a considerable amount of radiation to that transmitted from the net pores directly. In this study, the radiation balance method was modified to estimate Π precisely. The amount of solar radiation scattered forward on the thread surfaces was estimated separately. Thus, the un-scattered solar radiation transmitted from the net pores directly, which describes the net porosity, Π could be estimated. This method, in addition to the image processing and the direct beam transmittance methods were used to estimate Π for different types of nets that are commonly used for shading structures in summer. Values of Π estimated by using the proposed method were in good accordance with those measured by the image processing method at a resolution of 4800 dpi. The direct beam transmittance and the radiation balance methods resulted in overestimation errors in the values of Π. This error strongly depends on the color of the net. The estimated errors were +14% for a green net and +37% for a white net when using the radiation balance method, and were +16% and +38%, respectively, when using the direct beam transmittance method. In the image processing method, a resolution of 2400 dpi is sufficient to estimate Π precisely and the higher resolutions showed no significant effect on the value of Π.

  15. Net one, net two: the primary care network income statement.

    Science.gov (United States)

    Halley, M D; Little, A W

    1999-10-01

    Although hospital-owned primary care practices have been unprofitable for most hospitals, some hospitals are achieving competitive advantage and sustainable practice operations. A key to the success of some has been a net income reporting tool that separates practice operating expenses from the costs of creating and operating a network of practices to help healthcare organization managers, physicians, and staff to identify opportunities to improve the network's financial performance. This "Net One, Net Two" reporting allows operations leadership to be held accountable for Net One expenses and strategic leadership to be held accountable for Net Two expenses.

  16. Proof Nets for Lambek Calculus

    NARCIS (Netherlands)

    Roorda, Dirk

    1992-01-01

    The proof nets of linear logic are adapted to the non-commutative Lambek calculus. A different criterion for soundness of proof nets is given, which gives rise to new algorithms for proof search. The order sensitiveness of the Lambek calculus is reflected by the planarity condition on proof nets;

  17. Net metering: zero electricity bill

    International Nuclear Information System (INIS)

    Mangi, A.; Khan, Z.

    2011-01-01

    Worldwide move towards renewable energy sources, environmental concerns and decentralization of the power sector have made net metering an attractive option for power generation at small scale. This paper discusses the net metering, economical issues of renewable sources in Pakistan, technical aspects, installation suitability according to varying terrain, existing utility rules and formulation of legislation for net metering making it economically attractive. (author)

  18. The Net Advance of Physics

    Science.gov (United States)

    THE NET ADVANCE OF PHYSICS Review Articles and Tutorials in an Encyclopædic Format Established 1995 [Link to MIT] Computer support for The Net Advance of Physics is furnished by The Massachusetts Newest Additions SPECIAL FEATURES: Net Advance RETRO: Nineteenth Century Physics History of Science

  19. Horizontal ichthyoplankton tow-net system with unobstructed net opening

    Science.gov (United States)

    Nester, Robert T.

    1987-01-01

    The larval fish sampler described here consists of a modified bridle, frame, and net system with an obstruction-free net opening and is small enough for use on boats 10 m or less in length. The tow net features a square net frame attached to a 0.5-m-diameter cylinder-on-cone plankton net with a bridle designed to eliminate all obstructions forward of the net opening, significantly reducing currents and vibrations in the water directly preceding the net. This system was effective in collecting larvae representing more than 25 species of fish at sampling depths ranging from surface to 10 m and could easily be used at greater depths.

  20. Master Robotic Net

    Directory of Open Access Journals (Sweden)

    Vladimir Lipunov

    2010-01-01

    Full Text Available The main goal of the MASTER-Net project is to produce a unique fast sky survey with all sky observed over a single night down to a limiting magnitude of 19-20. Such a survey will make it possible to address a number of fundamental problems: search for dark energy via the discovery and photometry of supernovae (including SNIa, search for exoplanets, microlensing effects, discovery of minor bodies in the Solar System, and space-junk monitoring. All MASTER telescopes can be guided by alerts, and we plan to observe prompt optical emission from gamma-ray bursts synchronously in several filters and in several polarization planes.

  1. Lifetime Net Merit vs. annualized net present value as measures of profitability of selection

    Science.gov (United States)

    Current USDA linear selection indexes such as Lifetime Net Merit (NM$) estimate lifetime profit given a combination of 13 traits. In these indexes, every animal gets credit for 2.78 lactations of the traits expressed per lactation, independent of its productive life (PL). Selection among animals wit...

  2. 47 CFR 32.4341 - Net deferred tax liability adjustments.

    Science.gov (United States)

    2010-10-01

    ... income tax charges and credits pertaining to Account 32.4361, Deferred tax regulatory adjustments—net. (b... be recorded in Account 4361 as required by paragraph (a) of this section. (3) The tax effects of... UNIFORM SYSTEM OF ACCOUNTS FOR TELECOMMUNICATIONS COMPANIES Instructions for Balance Sheet Accounts § 32...

  3. New method for electric equivalents synthesis expressed in digital filters form for transitory simulations in real time for great power nets; Novo metodo para sintese de equivalentes eletricos a filtros digitais para simulacao de transitorios em tempo real em redes eletricas de grande porte

    Energy Technology Data Exchange (ETDEWEB)

    Pereira, Clever [Minas Gerais Univ., Belo Horizonte, MG (Brazil). Nucleo de Desenvolvimento Cientifico e Tecnologico em Descargas Atmosfericas]. E-mail: clever@cpdee.ufmg.br; Carneiro Junior, Sandoval [Universidade Federal, Rio de Janeiro, RJ (Brazil). Coordenacao dos Programas de Pos-graduacao de Engenharia; Szczupak, Jacques [Pontificia Univ. Catolica do Rio de Janeiro, RJ (Brazil)

    2001-07-01

    This article presents a new method to obtain subtransmission nets equivalents, expressed in form of digital filters of finite answer to the impulse, for transitory simulations in great power nets. Initially, it has been made considerations in the way of obtaining these filters, showing that they basically have been synthesized from the impedance and admittance functions of the secondary electric net to be processed in terms of equivalents in the domain of the w analogical frequency. It also is shown the transference technique to the time domain, in which it is used the z plane of the digital frequencies as an intermediate plane, being obtained from this way a set of equations susceptible of being implemented in program of transitory simulation in the time domain. The evaluation of this new method and evaluation of the reduction effect in the order of representative filters of the equivalents, are executed through the comparison of simulations which use the new technique together with other ones coming from EMTP. The obtained replies have demonstrated the effectiveness of the proposed method, opening new possibilities for transitory simulations in great power nets.

  4. Load Matching and Grid Interaction of Net Zero Energy Buildings

    DEFF Research Database (Denmark)

    Voss, Karsten; Candanedo, José A.; Geier, Sonja

    2010-01-01

    of seasonal energy storage on-site. Even though the wording “Net Zero Energy Building” focuses on the annual energy balance, large differences may occur between solution sets in the amount of grid interaction needed to reach the goal. The paper reports on the analysis of example buildings concerning the load......“Net Zero Energy Building” has become a prominent wording to describe the synergy of energy efficient building and renewable energy utilization to reach a balanced energy budget over a yearly cycle. Taking into account the energy exchange with a grid infrastructure overcomes the limitations...... matching and grid interaction. Indices to describe both issues are proposed and foreseen as part of a harmonized definition framework. The work is part of subtask A of the IEA SHCP Task40/ECBCS Annex 52: “Towards Net Zero Energy Solar Buildings”....

  5. Limitations of shallow nets approximation.

    Science.gov (United States)

    Lin, Shao-Bo

    2017-10-01

    In this paper, we aim at analyzing the approximation abilities of shallow networks in reproducing kernel Hilbert spaces (RKHSs). We prove that there is a probability measure such that the achievable lower bound for approximating by shallow nets can be realized for all functions in balls of reproducing kernel Hilbert space with high probability, which is different with the classical minimax approximation error estimates. This result together with the existing approximation results for deep nets shows the limitations for shallow nets and provides a theoretical explanation on why deep nets perform better than shallow nets. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Shielding calculations for NET

    International Nuclear Information System (INIS)

    Verschuur, K.A.; Hogenbirk, A.

    1991-05-01

    In the European Fusion Technology Programme there is only a small activity on research and development for fusion neutronics. Never-the-less, looking further than blanket design now, as ECN is getting involved in design of radiation shields for the coils and biological shields, it becomes apparent that fusion neutronics as a whole still needs substantial development. Existing exact codes for calculation of complex geometries like MCNP and DORT/TORT are put over the limits of their numerical capabilities, whilst approximate codes for complex geometries like FURNACE and MERCURE4 are put over the limits of their modelling capabilities. The main objective of this study is just to find out how far we can get with existing codes in obtaining reliable values for the radiation levels inside and outside the cryostat/shield during operation and after shut-down. Starting with a 1D torus model for preliminary parametric studies, more dimensional approximation of the torus or parts of it including the main heterogeneities should follow. Regular contacts with the NET-Team are kept, to be aware of main changes in NET design that might affect our calculation models. Work on the contract started 1 July 1990. The technical description of the contract is given. (author). 14 refs.; 4 figs.; 1 tab

  7. Balance Disorders

    Science.gov (United States)

    ... vertigo. If you have additional problems with motor control, such as weakness, slowness, tremor, or rigidity, you can lose your ability to recover properly from imbalance. This raises the risk of falling and injury. What are some types of balance disorders? There are more than a dozen different ...

  8. Balancing Eggs

    Science.gov (United States)

    Mills, Allan

    2014-01-01

    Theory predicts that an egg-shaped body should rest in stable equilibrium when on its side, balance vertically in metastable equilibrium on its broad end and be completely unstable on its narrow end. A homogeneous solid egg made from wood, clay or plastic behaves in this way, but a real egg will not stand on either end. It is shown that this…

  9. MATHeCADEMY.net

    OpenAIRE

    Tarp, Allan

    2007-01-01

    Mathematics itself avoids blunders by being well defined and well proved. However, mathematics education fails its goal by making blunder after blunder at all levels from grade 1 to 12. This paper uses the techniques of natural learning and natural research to separate natural mathematics from killer-mathematics. Two digit numbers, addition, fractions, balancing equations, and calculus are examples of mathematics that has been turned upside down creating the metamatism that killed mathemati...

  10. Magnesium balances and 28Mg studies in man

    International Nuclear Information System (INIS)

    Spencer, H.; Schwartz, R.; Osis, D.

    1988-01-01

    The intestinal absorption of magnesium was determined under strictly controlled dietary conditions in patients with normal renal function and also in patients with chronic renal failure. The average net absorption of magnesium of patients with normal renal function, expressed as percent of the magnesium intake, was 48.5%, while that of patients with chronic renal failure was significantly lower, 17%. Increasing the calcium intake from a low calcium intake of 200 mg/day to different higher intake levels up to 2000 mg/day did not change the magnesium balance nor the net absorption of magnesium of both types of patients. The lack of effect of the higher calcium intake on the absorption of magnesium was confirmed in 28 Mg studies in which an oral dose of 28 Mg, as the chloride, was given. The excretion of the absorbed magnesium into the intestine, the endogenous fecal magnesium, was low. Also, increasing the phosphorus intake up to 2000 mg/day in subjects with normal renal function did not affect the magnesium balance, regardless of the calcium intake

  11. Remote assessment of net shore drift along the west coast of India

    Digital Repository Service at National Institute of Oceanography (India)

    Kunte, P.D.; Wagle, B.G.; Sugimori, Y.

    -directional, net major sediment transport is southward. The geomorphic study identified possible sediment sources and sinks. Contributions of sources and losses due to sinks are assessed. The sediment balance is positive overall, and is reflected in large spits...

  12. Mars MetNet Mission Status

    Science.gov (United States)

    Harri, Ari-Matti; Aleksashkin, Sergei; Arruego, Ignacio; Schmidt, Walter; Genzer, Maria; Vazquez, Luis; Haukka, Harri

    2015-04-01

    descent phase starting shortly after separation from the spacecraft. MetNet Mission payload instruments are specially designed to operate in very low power conditions. MNL flexible solar panels provides a total of approximately 0.7-0.8 W of electric power during the daylight time. As the provided power output is insufficient to operate all instruments simultaneously they are activated sequentially according to a specially designed cyclogram table which adapts itself to the different environmental constraints. 3. Mission Status Full Qualification Model (QM) of the MetNet landing unit with the Precursor Mission payload is currently under functional tests. In near future the QM unit will be exposed to environmental tests with qualification levels including vibrations, thermal balance, thermal cycling and mechanical impact shock. One complete flight unit of the entry, descent and landing systems (EDLS) has been manufactured and tested with acceptance levels. Another flight-like EDLS has been exposed to most of the qualification tests, and hence it may be used for flight after refurbishments. Accordingly two flight-capable EDLS systems exist. The eventual goal is to create a network of atmospheric observational posts around the Martian surface. Even if the MetNet mission is focused on the atmospheric science, the mission payload will also include additional kinds of geophysical instrumentation. The next step in the MetNet Precursor Mission to demonstrate the technical robustness and scientific capabilities of the MetNet type of landing vehicle. Definition of the Precursor Mission and discussions on launch opportunities are currently under way. The baseline program development funding exists for the next five years. Flight unit manufacture of the payload bay takes about 18 months, and it will be commenced after the Precursor Mission has been defined. References [1] http://metnet.fmi.fi

  13. The equivalency between logic Petri workflow nets and workflow nets.

    Science.gov (United States)

    Wang, Jing; Yu, ShuXia; Du, YuYue

    2015-01-01

    Logic Petri nets (LPNs) can describe and analyze batch processing functions and passing value indeterminacy in cooperative systems. Logic Petri workflow nets (LPWNs) are proposed based on LPNs in this paper. Process mining is regarded as an important bridge between modeling and analysis of data mining and business process. Workflow nets (WF-nets) are the extension to Petri nets (PNs), and have successfully been used to process mining. Some shortcomings cannot be avoided in process mining, such as duplicate tasks, invisible tasks, and the noise of logs. The online shop in electronic commerce in this paper is modeled to prove the equivalence between LPWNs and WF-nets, and advantages of LPWNs are presented.

  14. The Equivalency between Logic Petri Workflow Nets and Workflow Nets

    Science.gov (United States)

    Wang, Jing; Yu, ShuXia; Du, YuYue

    2015-01-01

    Logic Petri nets (LPNs) can describe and analyze batch processing functions and passing value indeterminacy in cooperative systems. Logic Petri workflow nets (LPWNs) are proposed based on LPNs in this paper. Process mining is regarded as an important bridge between modeling and analysis of data mining and business process. Workflow nets (WF-nets) are the extension to Petri nets (PNs), and have successfully been used to process mining. Some shortcomings cannot be avoided in process mining, such as duplicate tasks, invisible tasks, and the noise of logs. The online shop in electronic commerce in this paper is modeled to prove the equivalence between LPWNs and WF-nets, and advantages of LPWNs are presented. PMID:25821845

  15. “THE NET MONETARY STATEMENT” AND “THE NET NON-MONETARY STATEMENT” – ASSESSMENT INDICATORS FOR THE FINANCIAL POSITION OF THE ENTITY

    Directory of Open Access Journals (Sweden)

    SORIN-CONSTANTIN DEACONU

    2012-10-01

    Full Text Available This paper examines two indicators, namely the net monetary statement and the net non-monetary statement. To determine and analyze them, we started with the classification of assets (monetary and non-monetary and liabilities (monetary and nonmonetary. The actual values of these elements were established on the basis of information supplied by the balance sheet, followed by the calculus of the net monetary statement and of the net non-monetary statement. These indicators provide relevant and reliable information to the users of financial statements and, in the future, they should be taken into account because they bring additional information about the financial position of the entity.

  16. Art/Net/Work

    DEFF Research Database (Denmark)

    Andersen, Christian Ulrik; Lindstrøm, Hanne

    2006-01-01

    The seminar Art|Net|Work deals with two important changes in our culture. On one side, the network has become essential in the latest technological development. The Internet has entered a new phase, Web 2.0, including the occurrence of as ‘Wiki’s’, ‘Peer-2-Peer’ distribution, user controlled...... on the ‘network’ itself as a phenomenon and are often using technological networks as a mean of production and distribution. This changes the artistic practice and the distribution channels of art works – and the traditional notions of ‘work’, ‘origin’ and ‘rights’ are increasingly perceived as limiting...... the praxis of the artist. We see different kinds of interventions and activism (including ‘hacktivism’) using the network as a way of questioning the invisible rules that govern public and semi-public spaces. Who ‘owns’ them? What kind of social relationships do they generate? On what principle...

  17. Net4Care

    DEFF Research Database (Denmark)

    Christensen, Henrik Bærbak; Hansen, Klaus Marius

    2012-01-01

    , health centers are getting larger and more distributed, and the number of healthcare professionals does not follow the trend in chronic diseases. All of this leads to a need for telemedical and mobile health applications. In a Danish context, these applications are often developed through local...... (innovative) initiatives with little regards for national and global (standardization) initiatives. A reason for this discrepancy is that the software architecture for national (and global) systems and standards are hard to understand, hard to develop systems based on, and hard to deploy. To counter this, we...... propose a software ecosystem approach for telemedicine applications, providing a framework, Net4Care, encapsulating national/global design decisions with respect to standardization while allowing for local innovation. This paper presents an analysis of existing systems, of requirements for a software...

  18. Partitioning of net carbon dioxide flux measured by automatic transparent chamber

    Science.gov (United States)

    Dyukarev, EA

    2018-03-01

    Mathematical model was developed for describing carbon dioxide fluxes at open sedge-sphagnum fen during growing season. The model was calibrated using the results of observations from automatic transparent chamber and it allows us to estimate autotrophic, heterotrophic and ecosystem respiration fluxes, gross and net primary vegetation production, and the net carbon balance.

  19. Solar and Net Radiation for Estimating Potential Evaporation from Three Vegetation Canopies

    Science.gov (United States)

    D.M. Amatya; R.W. Skaggs; G.W. Cheschier; G.P. Fernandez

    2000-01-01

    Solar and net radiation data are frequent/y used in estimating potential evaporation (PE) from various vegetative surfaces needed for water balance and hydrologic modeling studies. Weather parameters such as air temperature, relative humidity, wind speed, solar radiation, and net radiation have been continuously monitored using automated sensors to estimate PE for...

  20. Zero Net Energy Myths and Modes of Thought

    Energy Technology Data Exchange (ETDEWEB)

    Rajkovich, Nicholas B.; Diamond, Rick; Burke, Bill

    2010-09-20

    The U.S. Department of Energy (DOE), the California Public Utilities Commission (CPUC), and a number of professional organizations have established a target of zero net energy (ZNE) in buildings by 2030. One definition of ZNE is a building with greatly reduced needs for energy through efficiency gains with the balance of energy needs supplied by renewable technologies. The push to ZNE is a response to research indicating that atmospheric concentrations of greenhouse gases have increased sharply since the eighteenth century, resulting in a gradual warming of the Earth?s climate. A review of ZNE policies reveals that the organizations involved frame the ZNE issue in diverse ways, resulting in a wide variety of myths and a divergent set of epistemologies. With federal and state money poised to promote ZNE, it is timely to investigate how epistemologies, meaning a belief system by which we take facts and convert them into knowledge upon which to take action, and the propagation of myths might affect the outcome of a ZNE program. This paper outlines myths commonly discussed in the energy efficiency and renewable energy communities related to ZNE and describes how each myth is a different way of expressing"the truth." The paper continues by reviewing a number of epistemologies common to energy planning, and concludes that the organizations involved in ZNE should work together to create a"collaborative rationality" for ZNE. Through this collaborative framework it is argued that we may be able to achieve the ZNE and greenhouse gas mitigation targets.

  1. High-level Petri Nets

    DEFF Research Database (Denmark)

    various journals and collections. As a result, much of this knowledge is not readily available to people who may be interested in using high-level nets. Within the Petri net community this problem has been discussed many times, and as an outcome this book has been compiled. The book contains reprints...... of some of the most important papers on the application and theory of high-level Petri nets. In this way it makes the relevant literature more available. It is our hope that the book will be a useful source of information and that, e.g., it can be used in the organization of Petri net courses. To make......High-level Petri nets are now widely used in both theoretical analysis and practical modelling of concurrent systems. The main reason for the success of this class of net models is that they make it possible to obtain much more succinct and manageable descriptions than can be obtained by means...

  2. Adjusting the general growth balance method for migration

    OpenAIRE

    Hill, Kenneth; Queiroz, Bernardo

    2010-01-01

    Death distribution methods proposed for death registration coverage by comparison with census age distributions assume no net migration. This assumption makes it problematic to apply these methods to sub-national and national populations affected by substantial net migration. In this paper, we propose and explore a two-step process in which the Growth Balance Equation is first used to estimate net migration rates, using a model of age-specific migration, and then it is used to compare the obs...

  3. Net neutrality and audiovisual services

    OpenAIRE

    van Eijk, N.; Nikoltchev, S.

    2011-01-01

    Net neutrality is high on the European agenda. New regulations for the communication sector provide a legal framework for net neutrality and need to be implemented on both a European and a national level. The key element is not just about blocking or slowing down traffic across communication networks: the control over the distribution of audiovisual services constitutes a vital part of the problem. In this contribution, the phenomenon of net neutrality is described first. Next, the European a...

  4. NetView technical research

    Science.gov (United States)

    1993-01-01

    This is the Final Technical Report for the NetView Technical Research task. This report is prepared in accordance with Contract Data Requirements List (CDRL) item A002. NetView assistance was provided and details are presented under the following headings: NetView Management Systems (NMS) project tasks; WBAFB IBM 3090; WPAFB AMDAHL; WPAFB IBM 3084; Hill AFB; McClellan AFB AMDAHL; McClellan AFB IBM 3090; and Warner-Robins AFB.

  5. Initial CAD investigations for NET

    International Nuclear Information System (INIS)

    Katz, F.; Leinemann, K.; Ludwig, A.; Marek, U.; Olbrich, W.; Schlechtendahl, E.G.

    1985-11-01

    This report summarizes the work done under contract no. 164/84-7/FU-D-/NET between the Commission of the European Communities and KfK during the period from June 1, 1984, through May 31, 1985. The following topics are covered in this report: Initial modelling of NET version NET2A, CAD system extension for remote handling studies, analysis of the CAD information structure, work related to the transfer of CAD information between KfK and the NET team. (orig.) [de

  6. Balancing Risk

    DEFF Research Database (Denmark)

    Nygaard, Lene; Rossen, Camilla Blach; Buus, Niels

    2015-01-01

    This study explored how eight pregnant women diagnosed with depression managed the decision whether or not to take antidepressants during pregnancy. In total, 11 interviews were conducted and analysed by means of constructivist grounded theory. The major category constructed was Balancing risk......, with two minor categories: Assessing depression and antidepressants and Evaluating the impact of significant others. The participants tried to make the safest decision, taking all aspects of their life into consideration. They described successful decision-making in the context of managing social norms...

  7. Rare, but challenging tumors: NET

    International Nuclear Information System (INIS)

    Ivanova, D.; Balev, B.

    2013-01-01

    Full text: Introduction: Gastroenteropancreatic Neuroendocrine Tumors (GEP - NET) are a heterogeneous group of tumors with different locations and many different clinical, histological, and imaging performance. In a part of them a secretion of various organic substances is present. The morbidity of GEP - NET in the EU is growing, and this leads to increase the attention to them. What you will learn: Imaging methods used for localization and staging of GEP - NET, characteristics of the study’s protocols; Classification of GEP - NET; Demonstration of typical and atypical imaging features of GEP - NET in patients registered at the NET Center at University Hospital ‘St. Marina’, Varna; Features of metastatic NET, The role of imaging in the evaluation of treatment response and follow-up of the patients. Discussion: The image semiotics analysis is based on 19 cases of GEP - NET registered NET Center at University Hospital ‘St. Marina’. The main imaging method is multidetector CT (MDCT), and magnetic resonance imaging (MRI ) has advantages in the evaluation of liver lesions and the local prevalence of anorectal tumors. In patients with advanced disease and liver lesions the assessment of skeletal involvement (MRI/ nuclear medical method) is mandatory. The majority of GEP - NET have not any specific imaging findings. Therefore it is extremely important proper planning and conducting of the study (MDCT and MR enterography; accurate assessment phase of scanning, positive and negative contrast). Conclusion: GEP - NET is a major diagnostic challenge due to the absence of typical imaging characteristics and often an overlap with those of the tumors of different origin can be observed. Therefore, a good knowledge of clinical and imaging changes occurring at different locations is needed. MDCT is the basis for the diagnosis, staging and follow-up of these neoplasms

  8. On Energy Balance and Production Costs in Tubular and Flat Panel Photobioreactors

    NARCIS (Netherlands)

    Norsker, N.H.; Barbosa, M.J.; Vermue, M.H.; Wijffels, R.H.

    2012-01-01

    Reducing mixing in both flat panel and tubular photobioreactors can result in a positive net energy balance with state-of-the-art technology and Dutch weather conditions. In the tubular photobioreactor, the net energy balance becomes positive at velocities <0.3 ms-1, at which point the biomass

  9. Watt and joule balances

    Science.gov (United States)

    Robinson, Ian A.

    2014-04-01

    balance group are in the initial phases of the design and construction of a watt balance and their paper provides valuable information on the design that they are building. The design of the main magnet of a watt balance is critical to its successful operation, and an important assumption of watt balance operation is that the field of the magnet in moving mode is equivalent to that in weighing mode. Sutton and Clarkson from MSL describe a novel magnet which is designed to address this issue. The international prototype of the kilogram is kept in air but, after redefinition, the best realizations of the mass unit will be in vacuum. In their paper Berry and Davidson from NPL describe progress in techniques which relate mass measured in vacuum to that measured in air. Such techniques will be essential for making the results of watt and joule balance measurements available to science and industry. Both the NIST and NPL Mark II (NRC) watt balances use knife edges to act as the pivots for the beam. Knife edges suffer from hysteresis which can produce systematic offsets during weighing. In their paper Choi (KRISS) and Robinson (NPL) describe the analysis of this problem using both finite element (FEM) techniques and a stand-alone balance designed for testing knife edges. The last two papers deal with the possible future of the watt balance technique. The BIPM simultaneous measurement scheme for the watt balance was originally conceived for operation at cryogenic temperatures with a superconducting coil. In their paper de Mirandes and her co-authors describe initial work on the principles of this superconducting variant of the BIPM watt balance and concentrate on the characteristics of the superconducting coil in comparison with those of a normal coil. The final paper is a good example of serendipity in which Kibble (Independent Consultant) was designing novel watt balances based on seismometer suspensions and Robinson (NPL) had derived a set of general expressions, which are

  10. Gastroenteropancreatic neuroendocrine tumors (GEP-NETS)

    International Nuclear Information System (INIS)

    Vargas Martinez, Cristian Camilo; Castano Llano, Rodrigo

    2010-01-01

    Gastroenteropancreatic neuroendocrine tumors (GEP-NETS) are rare neoplasms which can occur anywhere in the gastrointestinal tract. Their particular characteristics include uptake of silver salts, neuroendocrine cell marker expression and hormonal secretory granules. Depending on their size, anatomical location and upon whether or not metastasis has occurred, these tumors can show different clinical patterns and have different prognoses. Early diagnosis is essential for treating these lesions and improving the patients' prognoses, but it requires a high degree of suspicion and confirmation by special testing. Surgical treatment is the first choice, but other medical therapy can be helpful for patients who have unresectable disease. This review presents the most relevant aspects of classification, morphology, methods of locating tumors, diagnosis and treatment of GEP-NETS. It presents only the Colombian experience in the epidemiology and management of these tumors.

  11. Annual Energy Balance Sheets 2001-2002

    International Nuclear Information System (INIS)

    2004-01-01

    During the year 2002 the primary supply of energy reached 629 TWh, which is 7.7 TWh less than 2001. The decrease originates mainly from the reduced electricity production from water power. Also the electricity production in nuclear power plants decreased by 4.5 TWh. If we were to look at the supplied energy for final consumption we will find a slightly rise by 1.8 TWh. The year 2002 was warmer than a 'normal' year and that consequently brings lower energy needs. Compared with 2001, 2002 was not warmer and a net electricity import of 5.4 TWh covered the energy needs. The energy use increased by 3.3 TWh between 2002 and 2001. The industry sector shows the largest rise by 2.9 TWh, nearly 2 per cent. Within that sector, energy from biomass fuel had a rise by 6.7 per cent. The household sector decreases its energy use by 2.7 per cent, and oil and electricity show the largest decrease. The proportionately high electricity price probably had a slowing down effect on the electricity use. The balance sheets of energy sources are showing the total supply and consumption of energy sources expressed in original units, i.e. units recorded in the primary statistics - mainly commercial units. The production of derived energy commodities is recorded on the supply - side of the balance sheets of energy sources, which is not the case in the energy balance sheets. The balance sheets of energy sources also include specifications of input--output and energy consumption in energy conversion industries. The energy balance sheets are based on primary data recorded in the balance sheets of energy sources, here expressed in a common energy unit, TJ. The production of derived energy is recorded in a second flow-step comprising energy turnover in energy conversion and is also specified in complementary input - output tables for energy conversion industries. The following items are shown in the energy balance sheets. 1.1 Inland supply of primary energy; 1.3 Import; 1.4 Export; 1.5 Changes in

  12. Net neutrality and audiovisual services

    NARCIS (Netherlands)

    van Eijk, N.; Nikoltchev, S.

    2011-01-01

    Net neutrality is high on the European agenda. New regulations for the communication sector provide a legal framework for net neutrality and need to be implemented on both a European and a national level. The key element is not just about blocking or slowing down traffic across communication

  13. Properties of porous netted materials

    International Nuclear Information System (INIS)

    Daragan, V.D.; Drozdov, B.G.; Kotov, A.Yu.; Mel'nikov, G.N.; Pustogarov, A.V.

    1987-01-01

    Hydraulic and strength characteristics, efficient heat conduction and inner heat exchange coefficient are experimentally studied for porous netted materials on the base of the brass nets as dependent on porosity, cell size and method of net laying. Results of the studies are presented. It is shown that due to anisotropy of the material properties the hydraulic resistance in the direction parallel to the nets plane is 1.3-1.6 times higher than in the perpendicular one. Values of the effective heat conduction in the direction perpendicular to the nets plane at Π>0.45 agree with the data from literature, at Π<0.45 a deviation from the calculated values is marked in the direction of the heat conduction decrease

  14. NET remote workstation

    International Nuclear Information System (INIS)

    Leinemann, K.

    1990-10-01

    The goal of this NET study was to define the functionality of a remote handling workstation and its hardware and software architecture. The remote handling workstation has to fulfill two basic functions: (1) to provide the man-machine interface (MMI), that means the interface to the control system of the maintenance equipment and to the working environment (telepresence) and (2) to provide high level (task level) supporting functions (software tools) during the maintenance work and in the preparation phase. Concerning the man-machine interface, an important module of the remote handling workstation besides the standard components of man-machine interfacing is a module for graphical scene presentation supplementing viewing by TV. The technique of integrated viewing is well known from JET BOOM and TARM control using the GBsim and KISMET software. For integration of equipment dependent MMI functions the remote handling workstation provides a special software module interface. Task level support of the operator is based on (1) spatial (geometric/kinematic) models, (2) remote handling procedure models, and (3) functional models of the equipment. These models and the related simulation modules are used for planning, programming, execution monitoring, and training. The workstation provides an intelligent handbook guiding the operator through planned procedures illustrated by animated graphical sequences. For unplanned situations decision aids are available. A central point of the architectural design was to guarantee a high flexibility with respect to hardware and software. Therefore the remote handling workstation is designed as an open system based on widely accepted standards allowing the stepwise integration of the various modules starting with the basic MMI and the spatial simulation as standard components. (orig./HP) [de

  15. Predisposition of cows to mastitis in non-infected mammary glands: effects of dietary-induced negative energy balance during mid-lactation on immune-related genes

    DEFF Research Database (Denmark)

    Moyes, Kasey; Drackley, James K; Morin, Dawn E

    2011-01-01

    Cows experiencing severe postpartal negative energy balance (NEB) are at greater risk of developing mastitis than cows in positive energy balance (PEB). Our objectives were to compare mammary tissue gene expression profiles between lactating cows (n = 5/treatment) subjected to feed restriction...... to induce NEB and cows fed ad libitum to maintain PEB in order to identify genes involved in immune response and cellular metabolism that may predispose cows to an intramammary infection in non-infected mammary gland. The NEB cows were feed-restricted to 60% of calculated net energy for lactation...... requirements, and cows fed PEB cows were fed the same diet ad libitum. At 5 days after feed restriction, one rear mammary gland from all cows was biopsied for RNA extraction and transcript profiling using microarray and quantitative PCR. Energy balance (NEB vs. PEB) resulted in 278 differentially expressed...

  16. Conformal Nets II: Conformal Blocks

    Science.gov (United States)

    Bartels, Arthur; Douglas, Christopher L.; Henriques, André

    2017-08-01

    Conformal nets provide a mathematical formalism for conformal field theory. Associated to a conformal net with finite index, we give a construction of the `bundle of conformal blocks', a representation of the mapping class groupoid of closed topological surfaces into the category of finite-dimensional projective Hilbert spaces. We also construct infinite-dimensional spaces of conformal blocks for topological surfaces with smooth boundary. We prove that the conformal blocks satisfy a factorization formula for gluing surfaces along circles, and an analogous formula for gluing surfaces along intervals. We use this interval factorization property to give a new proof of the modularity of the category of representations of a conformal net.

  17. Pro asynchronous programming with .NET

    CERN Document Server

    Blewett, Richard; Ltd, Rock Solid Knowledge

    2014-01-01

    Pro Asynchronous Programming with .NET teaches the essential skill of asynchronous programming in .NET. It answers critical questions in .NET application development, such as: how do I keep my program responding at all times to keep my users happy how do I make the most of the available hardware how can I improve performanceIn the modern world, users expect more and more from their applications and devices, and multi-core hardware has the potential to provide it. But it takes carefully crafted code to turn that potential into responsive, scalable applications.With Pro Asynchronous Programming

  18. Regulation of Human Macrophage M1–M2 Polarization Balance by Hypoxia and the Triggering Receptor Expressed on Myeloid Cells-1

    Directory of Open Access Journals (Sweden)

    Federica Raggi

    2017-09-01

    Full Text Available Macrophages (Mf are a heterogeneous population of tissue-resident professional phagocytes and a major component of the leukocyte infiltrate at sites of inflammation, infection, and tumor growth. They can undergo diverse forms of activation in response to environmental factors, polarizing into specialized functional subsets. A common hallmark of the pathologic environment is represented by hypoxia. The impact of hypoxia on human Mf polarization has not been fully established. The objective of this study was to elucidate the effects of a hypoxic environment reflecting that occurring in vivo in diseased tissues on the ability of human Mf to polarize into classically activated (proinflammatory M1 and alternatively activated (anti-inflammatory M2 subsets. We present data showing that hypoxia hinders Mf polarization toward the M1 phenotype by decreasing the expression of T cell costimulatory molecules and chemokine homing receptors and the production of proinflammatory, Th1-priming cytokines typical of classical activation, while promoting their acquisition of phenotypic and secretory features of alternative activation. Furthermore, we identify the triggering receptor expressed on myeloid cells (TREM-1, a member of the Ig-like immunoregulatory receptor family, as a hypoxia-inducible gene in Mf and demonstrate that its engagement by an agonist Ab reverses the M2-polarizing effect of hypoxia imparting a M1-skewed phenotype to Mf. Finally, we provide evidence that Mf infiltrating the inflamed hypoxic joints of children affected by oligoarticular juvenile idiopatic arthritis express high surface levels of TREM-1 associated with predominant M1 polarization and suggest the potential of this molecule in driving M1 proinflammatory reprogramming in the hypoxic synovial environment.

  19. Regulation of Human Macrophage M1–M2 Polarization Balance by Hypoxia and the Triggering Receptor Expressed on Myeloid Cells-1

    Science.gov (United States)

    Raggi, Federica; Pelassa, Simone; Pierobon, Daniele; Penco, Federica; Gattorno, Marco; Novelli, Francesco; Eva, Alessandra; Varesio, Luigi; Giovarelli, Mirella; Bosco, Maria Carla

    2017-01-01

    Macrophages (Mf) are a heterogeneous population of tissue-resident professional phagocytes and a major component of the leukocyte infiltrate at sites of inflammation, infection, and tumor growth. They can undergo diverse forms of activation in response to environmental factors, polarizing into specialized functional subsets. A common hallmark of the pathologic environment is represented by hypoxia. The impact of hypoxia on human Mf polarization has not been fully established. The objective of this study was to elucidate the effects of a hypoxic environment reflecting that occurring in vivo in diseased tissues on the ability of human Mf to polarize into classically activated (proinflammatory M1) and alternatively activated (anti-inflammatory M2) subsets. We present data showing that hypoxia hinders Mf polarization toward the M1 phenotype by decreasing the expression of T cell costimulatory molecules and chemokine homing receptors and the production of proinflammatory, Th1-priming cytokines typical of classical activation, while promoting their acquisition of phenotypic and secretory features of alternative activation. Furthermore, we identify the triggering receptor expressed on myeloid cells (TREM)-1, a member of the Ig-like immunoregulatory receptor family, as a hypoxia-inducible gene in Mf and demonstrate that its engagement by an agonist Ab reverses the M2-polarizing effect of hypoxia imparting a M1-skewed phenotype to Mf. Finally, we provide evidence that Mf infiltrating the inflamed hypoxic joints of children affected by oligoarticular juvenile idiopatic arthritis express high surface levels of TREM-1 associated with predominant M1 polarization and suggest the potential of this molecule in driving M1 proinflammatory reprogramming in the hypoxic synovial environment. PMID:28936211

  20. Emergency Preparedness and Response: A Safety Net

    Energy Technology Data Exchange (ETDEWEB)

    Aaltonen, H., E-mail: hannele.aaltonen@stuk.fi [Radiation and Nuclear Safety Authority (STUK), Helsinki (Finland)

    2014-10-15

    Full text: The objective of nuclear regulatory work is to prevent accidents. Nevertheless, possibility of a severe accident cannot be totally excluded, which makes a safety net, efficient emergency preparedness and response, necessary. Should the possibility of accidents be rejected, the result would be in the worst case inadequate protection of population, functions of society, and environment from harmful effects of radiation. Adequate resources for maintenance and development of emergency arrangement are crucial. However, they need to be balanced taking into account risks assessments, justified expectations of society, and international requirements. To successfully respond to an emergency, effective emergency preparedness, such as up-to-date plans and procedures, robust arrangements and knowledgeable and regularly trained staff are required. These, however, are not enough without willingness and proactive attitude to • communicate in a timely manner; • co-operate and coordinate actions; • provide and receive assistance; and • evaluate and improve emergency arrangements. In the establishment and development of emergency arrangements, redundant and diverse means or tools used are needed in, for example, communication and assessment of hazard. Any severe nuclear emergency would affect all countries either directly or indirectly. Thus, national emergency arrangements have to be compatible to the extent practicable with international emergency arrangements. It is important to all countries that the safety nets of emergency arrangements are reliable - and operate efficiently in a coordinated manner when needed - on national, regional and international level. (author)

  1. CLIMATIC FORECASTING OF NET INFILTRATION AT YUCCA MOUNTAIN, USING ANALOGUE METEOROLOGICAL DATA

    International Nuclear Information System (INIS)

    B. Faybishenko

    2005-01-01

    Net infiltration is a key hydrologic parameter that controls the rate of deep percolation through the unsaturated zone, the groundwater recharge, radionuclide transport, and seepage into the underground tunnels. Because net infiltration is largely affected by climatic conditions, future changes in climatic conditions will potentially alter net infiltration. The objectives of this presentation are to: (1) Present a conceptual model and a semi-empirical approach for regional, climatic forecasting of net infiltration, based on the precipitation and temperature data from analogue meteorological stations, and (2) Demonstrate the results of forecasting net infiltration for future climates--interglacial, monsoon and glacial--over the Yucca Mountain region for the period of 500,000 years. Calculations of the net infiltration were performed using a modified Budyko's water-balance model, for which potential evapotranspiration was evaluated from the temperature-based Thornthwaite formula. (Both Budyko's and Thornthwaite's formulae have been used broadly in hydrological studies.) The results of calculations were used for ranking net infiltration, along with the aridity and precipitation-effectiveness (P-E) indexes, for future climatic scenarios. Using this approach, we determined a general trend of increasing net infiltration from the present-day (interglacial) climate to monsoon, intermediate (glacial transition), and then to the glacial climate. Ranking of the aridity and P-E indexes is practically the same as that of net infiltration. The validation of the computed net infiltration rates yielded a good match with other field and modeling study results of groundwater recharge and net infiltration evaluation

  2. KM3NeT

    CERN Multimedia

    KM3NeT is a large scale next-generation neutrino telescope located in the deep waters of the Mediterranean Sea, optimized for the discovery of galactic neutrino sources emitting in the TeV energy region.

  3. Pickering nuclear fish diversion net

    Energy Technology Data Exchange (ETDEWEB)

    Xiao, J.; Lew, A. [Ontario Power Generation, Toronto, Ontario (Canada)

    2013-07-01

    Pickering Fish Diversion Net - An Engineered Environmental Solution that has significantly reduced fish impingement at the Pickering Nuclear Facility. Note: As a recent urgent request/discussed by Mark Elliot, CNE-OPG and Jacques Plourde, CNS.

  4. PolicyNet Publication System

    Data.gov (United States)

    Social Security Administration — The PolicyNet Publication System project will merge the Oracle-based Policy Repository (POMS) and the SQL-Server CAMP system (MSOM) into a new system with an Oracle...

  5. Net Neutrality: Background and Issues

    National Research Council Canada - National Science Library

    Gilroy, Angele A

    2006-01-01

    .... The move to place restrictions on the owners of the networks that compose and provide access to the Internet, to ensure equal access and nondiscriminatory treatment, is referred to as "net neutrality...

  6. Analisis Determinan Net Ekspor Indonesia

    OpenAIRE

    Daulay, Rahmawaty

    2010-01-01

    This study is to analyzing empirically among Indonesia GDP, trade partnership GDP (Malaysia, Singapore, US and Thailand) and real exchange rate toward Indonesia Net Export. To find out which one from those three variables is significant in order to fluctuating (increasing or decreasing) Indonesia Net Export either in the short run or in the long run. Data collection is obtained using secondary data, namely Indonesia GDP, Malaysia GDP, Singapura GDP, US GDP, Thailand GDP and real exchange rate...

  7. NetBeans GUI Builder

    OpenAIRE

    Pusiankova, Tatsiana

    2009-01-01

    This work aims at making readers familiar with the powerful tool NetBeans IDE GUI Builder and helping them make their first steps to creation of their own graphical user interface in the Java programming language. The work includes theoretical description of NetBeans IDE GUI Builder, its most important characteristics and peculiarities and also a set of practical instructions that will help readers in creation of their first GUI. The readers will be introduced to the environment of this tool ...

  8. Forum shopping for ex-post gas-balancing services

    International Nuclear Information System (INIS)

    Keyaerts, Nico; D'haeseleer, William

    2014-01-01

    The patchwork of different imbalance-settlement rules in geographically adjacent gas regions induces shippers to go “forum shopping” to minimize costs of ex-post balancing services. This shopping increases efficiency, and thus welfare of the shippers, on the one hand. The impact on net efficiency is dependent on the relative incentives provided by different balancing mechanisms and the relative system-balancing costs that the transmission-system operators face to offer balancing services to unbalanced shippers, on the other hand. If the gas-balancing mechanism and the system-balancing costs are aligned, net efficiency in the combined gas system will rise. Our results demonstrate that such an outcome is not guaranteed. Hence, market integration without properly checking compatibility of balancing rules can improve shipper efficiency at the cost of reducing overall efficiency. The latter outcome should clearly be avoided by policy makers and European regulators whose primary concern should be overall efficiency as this provides fair and efficient prices for gas consumers and a higher utility for society. - Highlights: • Transnational gas-shipper activity increases shipper profit. • Balancing rules in multi-region gas markets are not always compatible. • Regional TSOs balance less efficiently if wrong incentives are provided. • Net efficiency is dependent on cost reflection of relative imbalance tariffs

  9. Basis Risk and Net Interest Income of Banks

    Directory of Open Access Journals (Sweden)

    Mielus Piotr

    2016-12-01

    Full Text Available The results of the banking sector are shaped primarily by commissions and net interest income. Net interest income is determined by the difference between the profitability of bank assets and liabilities. In the case when a different method is used to determine interest for each side of the balance sheet, there occurs a basis risk that may lead to the deterioration in the net interest income of the sector. This is the situation in the Polish banking sector, which is characterized by the presence of variable interest rates for long-term assets and fixed interest rates for short-term liabilities. The study aims to verify the following thesis: in an environment of falling interest rates we can observe the deterioration in net interest income of the banking sector, as a result of the materialization of the basis risk. The authors of the article state that the source of the basis risk is the mismatch between the reference rate used to define the interest flow of loans and the actual cost of financing the balance through term deposits collected from non-financial entities.

  10. Multiflavor string-net models

    Science.gov (United States)

    Lin, Chien-Hung

    2017-05-01

    We generalize the string-net construction to multiple flavors of strings, each of which is labeled by the elements of an Abelian group Gi. The same flavor of strings can branch, while different flavors of strings can cross one another and thus they form intersecting string nets. We systematically construct the exactly soluble lattice Hamiltonians and the ground-state wave functions for the intersecting string-net condensed phases. We analyze the braiding statistics of the low-energy quasiparticle excitations and find that our model can realize all the topological phases as the string-net model with group G =∏iGi . In this respect, our construction provides various ways of building lattice models which realize topological order G , corresponding to different partitions of G and thus different flavors of string nets. In fact, our construction concretely demonstrates the Künneth formula by constructing various lattice models with the same topological order. As an example, we construct the G =Z2×Z2×Z2 string-net model which realizes a non-Abelian topological phase by properly intersecting three copies of toric codes.

  11. Importance of energy balance in agriculture.

    Science.gov (United States)

    Meco, R.; Moreno, M. M.; Lacasta, C.; Tarquis, A. M.; Moreno, C.

    2012-04-01

    inputs) ones. Energy outputs (EO) are considered as the calorific value of the harvested biomass (main products and sub-products), calculated from the total production (kg/ha) and its corresponding energy coefficient (strongly correlated to the biochemical composition of the products). Based on energy inputs and outputs, energy efficiency can be expressed as (i) net energy produced (NE) (also known as energy gain or energy balance, calculated as EI-EO and expressed as MJ/ha), (ii) the energy output/input ratio (also known as energy efficiency and calculated as EO/EI), and (iii) energy productivity (EP) (Crop yield/EI, expressed as kg/MJ). Funding provided by Spanish Ministerio de Ciencia e Innovación (MICINN) through project no. AGL2010-21501/AGR is greatly appreciated.

  12. Lesson "Balance in Nature

    Science.gov (United States)

    Chapanova, V.

    2012-04-01

    Lesson "Balance in Nature" This simulation game-lesson (Balance in Nature) gives an opportunity for the students to show creativity, work independently, and to create models and ideas. It creates future-oriented thought connected to their experience, allowing them to propose solutions for global problems and personal responsibility for their activities. The class is divided in two teams. Each team chooses questions. 1. Question: Pollution in the environment. 2. Question: Care for nature and climate. The teams work on the chosen tasks. They make drafts, notes and formulate their solutions on small pieces of paper, explaining the impact on nature and society. They express their points of view using many different opinions. This generates alternative thoughts and results in creative solutions. With the new knowledge and positive behaviour defined, everybody realizes that they can do something positive towards nature and climate problems and the importance of individuals for solving global problems is evident. Our main goal is to recover the ecological balance, and everybody explains his or her own well-grounded opinions. In this work process the students obtain knowledge, skills and more responsible behaviour. This process, based on his or her own experience, dialogue and teamwork, helps the participant's self-development. Making the model "human↔ nature" expresses how human activities impact the natural Earth and how these impacts in turn affect society. Taking personal responsibility, we can reduce global warming and help the Earth. By helping nature we help ourselves. Teacher: Veselina Boycheva-Chapanova " Saint Patriarch Evtimii" Scholl Str. "Ivan Vazov"-19 Plovdiv Bulgaria

  13. Core binding factor beta (Cbfβ) controls the balance of chondrocyte proliferation and differentiation by upregulating Indian hedgehog (Ihh) expression and inhibiting parathyroid hormone-related protein receptor (PPR) expression in postnatal cartilage and bone formation.

    Science.gov (United States)

    Tian, Fei; Wu, Mengrui; Deng, Lianfu; Zhu, Guochun; Ma, Junqing; Gao, Bo; Wang, Lin; Li, Yi-Ping; Chen, Wei

    2014-07-01

    Core binding factor beta (Cbfβ) is essential for embryonic bone morphogenesis. Yet the mechanisms by which Cbfβ regulates chondrocyte proliferation and differentiation as well as postnatal cartilage and bone formation remain unclear. Hence, using paired-related homeobox transcription factor 1-Cre (Prx1-Cre) mice, mesenchymal stem cell-specific Cbfβ-deficient (Cbfβ(f/f) Prx1-Cre) mice were generated to study the role of Cbfβ in postnatal cartilage and bone development. These mutant mice survived to adulthood but exhibited severe sternum and limb malformations. Sternum ossification was largely delayed in the Cbfβ(f/f) Prx1-Cre mice and the xiphoid process was noncalcified and enlarged. In newborn and 7-day-old Cbfβ(f/f) Prx1-Cre mice, the resting zone was dramatically elongated, the proliferation zone and hypertrophic zone of the growth plates were drastically shortened and disorganized, and trabecular bone formation was reduced. Moreover, in 1-month-old Cbfβ(f/f) Prx1-Cre mice, the growth plates were severely deformed and trabecular bone was almost absent. In addition, Cbfβ deficiency impaired intramembranous bone formation both in vivo and in vitro. Interestingly, although the expression of Indian hedgehog (Ihh) was largely reduced, the expression of parathyroid hormone-related protein (PTHrP) receptor (PPR) was dramatically increased in the Cbfβ(f/f) Prx1-Cre growth plate, indicating that that Cbfβ deficiency disrupted the Ihh-PTHrP negative regulatory loop. Chromatin immunoprecipitation (ChIP) analysis and promoter luciferase assay demonstrated that the Runx/Cbfβ complex binds putative Runx-binding sites of the Ihh promoter regions, and also the Runx/Cbfβ complex directly upregulates Ihh expression at the transcriptional level. Consistently, the expressions of Ihh target genes, including CyclinD1, Ptc, and Pthlh, were downregulated in Cbfβ-deficient chondrocytes. Taken together, our study reveals not only that Cbfβ is essential for chondrocyte

  14. Late-onset running biphasically improves redox balance, energy- and methylglyoxal-related status, as well as SIRT1 expression in mouse hippocampus.

    Directory of Open Access Journals (Sweden)

    Stefano Falone

    Full Text Available Despite the active research in this field, molecular mechanisms underlying exercise-induced beneficial effects on brain physiology and functions are still matter of debate, especially with regard to biological processes activated by regular exercise affecting the onset and progression of hippocampal aging in individuals unfamiliar with habitual physical activity. Since such responses seem to be mediated by changes in antioxidative, antiglycative and metabolic status, a possible exercise-induced coordinated response involving redox, methylglyoxal- and sirtuin-related molecular networks may be hypothesized. In this study, hippocampi of CD1 mice undergoing the transition from mature to middle age were analyzed for redox-related profile, oxidative and methylglyoxal-dependent damage patterns, energy metabolism, sirtuin1 and glyoxalase1 expression after a 2- or 4-mo treadmill running program. Our findings suggested that the 4-mo regular running lowered the chance of dicarbonyl and oxidative stress, activated mitochondrial catabolism and preserved sirtuin1-related neuroprotection. Surprisingly, the same cellular pathways were negatively affected by the first 2 months of exercise, thus showing an interesting biphasic response. In conclusion, the duration of exercise caused a profound shift in the response to regular running within the rodent hippocampus in a time-dependent fashion. This research revealed important details of the interaction between exercise and mammal hippocampus during the transition from mature to middle age, and this might help to develop non-pharmacological approaches aimed at retarding brain senescence, even in individuals unfamiliar with habitual exercise.

  15. Microaerobic conversion of xylose to ethanol in recombinant Saccharomyces cerevisiae SX6(MUT) expressing cofactor-balanced xylose metabolic enzymes and deficient in ALD6.

    Science.gov (United States)

    Jo, Sung-Eun; Seong, Yeong-Je; Lee, Hyun-Soo; Lee, Soo Min; Kim, Soo-Jung; Park, Kyungmoon; Park, Yong-Cheol

    2016-06-10

    Xylose is a major monosugar in cellulosic biomass and should be utilized for cost-effective ethanol production. In this study, xylose-converting ability of recombinant Saccharomyces cerevisiae SX6(MUT) expressing NADH-preferring xylose reductase mutant (R276H) and other xylose-metabolic enzymes, and deficient in aldehyde dehydrogenase 6 (Ald6p) were characterized at microaerobic conditions using various sugar mixtures. The reduction of air supply from 0.5vvm to 0.1vvm increased specific ethanol production rate by 75% and did not affect specific xylose consumption rate. In batch fermentations using various concentrations of xylose (50-104g/L), higher xylose concentration enhanced xylose consumption rate and ethanol productivity but reduced ethanol yield, owing to the accumulation of xylitol and glycerol from xylose. SX6(MUT) consumed monosugars in pitch pine hydrolysates and produced 23.1g/L ethanol from 58.7g/L sugars with 0.39g/g ethanol yield, which was 14% higher than the host strain of S. cerevisiae D452-2 without the xylose assimilating enzymes. In conclusion, S. cerevisiae SX6(MUT) was characterized to possess high xylose-consuming ability in microaerobic conditions and a potential for ethanol production from cellulosic biomass. Copyright © 2016 Elsevier B.V. All rights reserved.

  16. Biodiversity offsets and the challenge of achieving no net loss.

    Science.gov (United States)

    Gardner, Toby A; VON Hase, Amrei; Brownlie, Susie; Ekstrom, Jonathan M M; Pilgrim, John D; Savy, Conrad E; Stephens, R T Theo; Treweek, Jo; Ussher, Graham T; Ward, Gerri; Ten Kate, Kerry

    2013-12-01

    Businesses, governments, and financial institutions are increasingly adopting a policy of no net loss of biodiversity for development activities. The goal of no net loss is intended to help relieve tension between conservation and development by enabling economic gains to be achieved without concomitant biodiversity losses. biodiversity offsets represent a necessary component of a much broader mitigation strategy for achieving no net loss following prior application of avoidance, minimization, and remediation measures. However, doubts have been raised about the appropriate use of biodiversity offsets. We examined what no net loss means as a desirable conservation outcome and reviewed the conditions that determine whether, and under what circumstances, biodiversity offsets can help achieve such a goal. We propose a conceptual framework to substitute the often ad hoc approaches evident in many biodiversity offset initiatives. The relevance of biodiversity offsets to no net loss rests on 2 fundamental premises. First, offsets are rarely adequate for achieving no net loss of biodiversity alone. Second, some development effects may be too difficult or risky, or even impossible, to offset. To help to deliver no net loss through biodiversity offsets, biodiversity gains must be comparable to losses, be in addition to conservation gains that may have occurred in absence of the offset, and be lasting and protected from risk of failure. Adherence to these conditions requires consideration of the wider landscape context of development and offset activities, timing of offset delivery, measurement of biodiversity, accounting procedures and rule sets used to calculate biodiversity losses and gains and guide offset design, and approaches to managing risk. Adoption of this framework will strengthen the potential for offsets to provide an ecologically defensible mechanism that can help reconcile conservation and development. Balances de Biodiversidad y el Reto de No Obtener P

  17. A Petri Net Definition of a System Description Language

    DEFF Research Database (Denmark)

    Jensen, Kurt; Kyng, Morten; Madsen, Ole Lehrmann

    1979-01-01

    This paper introduces a language for the description of systems with concurrency, and presents a formal definition of its semantics. The language is based on Delta and the semantic model is an extension of Petri nets with a data part and with expressions attached to transitions and to places....

  18. MATT: Multi Agents Testing Tool Based Nets within Nets

    Directory of Open Access Journals (Sweden)

    Sara Kerraoui

    2016-12-01

    As part of this effort, we propose a model based testing approach for multi agent systems based on such a model called Reference net, where a tool, which aims to providing a uniform and automated approach is developed. The feasibility and the advantage of the proposed approach are shown through a short case study.

  19. A functional and transcriptomic analysis of NET1 bioactivity in gastric cancer

    LENUS (Irish Health Repository)

    Bennett, Gayle

    2011-02-01

    Abstract Background NET1, a RhoA guanine exchange factor, is up-regulated in gastric cancer (GC) tissue and drives the invasive phenotype of this disease. In this study, we aimed to determine the role of NET1 in GC by monitoring the proliferation, motility and invasion of GC cells in which NET1 has been stably knocked down. Additionally, we aimed to determine NET1-dependent transcriptomic events that occur in GC. Methods An in vitro model of stable knockdown of NET1 was achieved in AGS human gastric adenocarcinoma cells via lentiviral mediated transduction of short-hairpin (sh) RNA targeting NET1. Knockdown was assessed using quantitative PCR. Cell proliferation was assessed using an MTS assay and cell migration was assessed using a wound healing scratch assay. Cell invasion was assessed using a transwell matrigel invasion assay. Gene expression profiles were examined using affymetrix oligonucleotide U133A expression arrays. A student\\'s t test was used to determine changes of statistical significance. Results GC cells were transduced with NET1 shRNA resulting in a 97% reduction in NET1 mRNA (p < 0.0001). NET1 knockdown significantly reduced the invasion and migration of GC cells by 94% (p < 0.05) and 24% (p < 0.001) respectively, while cell proliferation was not significantly altered following NET1 knockdown. Microarray analysis was performed on non-target and knockdown cell lines, treated with and without 10 μM lysophosphatidic acid (LPA) allowing us to identify NET1-dependent, LPA-dependent and NET1-mediated LPA-induced gene transcription. Differential gene expression was confirmed by quantitative PCR. Shortlisted NET1-dependent genes included STAT1, TSPAN1, TGFBi and CCL5 all of which were downregulatd upon NET1 downregulation. Shortlisted LPA-dependent genes included EGFR and PPARD where EGFR was upregulated and PPARD was downregulated upon LPA stimulation. Shortlisted NET1 and LPA dependent genes included IGFR1 and PIP5K3. These LPA induced genes were

  20. A functional and transcriptomic analysis of NET1 bioactivity in gastric cancer

    International Nuclear Information System (INIS)

    Bennett, Gayle; Sadlier, Denise; Doran, Peter P; MacMathuna, Padraic; Murray, David W

    2011-01-01

    NET1, a RhoA guanine exchange factor, is up-regulated in gastric cancer (GC) tissue and drives the invasive phenotype of this disease. In this study, we aimed to determine the role of NET1 in GC by monitoring the proliferation, motility and invasion of GC cells in which NET1 has been stably knocked down. Additionally, we aimed to determine NET1-dependent transcriptomic events that occur in GC. An in vitro model of stable knockdown of NET1 was achieved in AGS human gastric adenocarcinoma cells via lentiviral mediated transduction of short-hairpin (sh) RNA targeting NET1. Knockdown was assessed using quantitative PCR. Cell proliferation was assessed using an MTS assay and cell migration was assessed using a wound healing scratch assay. Cell invasion was assessed using a transwell matrigel invasion assay. Gene expression profiles were examined using affymetrix oligonucleotide U133A expression arrays. A student's t test was used to determine changes of statistical significance. GC cells were transduced with NET1 shRNA resulting in a 97% reduction in NET1 mRNA (p < 0.0001). NET1 knockdown significantly reduced the invasion and migration of GC cells by 94% (p < 0.05) and 24% (p < 0.001) respectively, while cell proliferation was not significantly altered following NET1 knockdown. Microarray analysis was performed on non-target and knockdown cell lines, treated with and without 10 μM lysophosphatidic acid (LPA) allowing us to identify NET1-dependent, LPA-dependent and NET1-mediated LPA-induced gene transcription. Differential gene expression was confirmed by quantitative PCR. Shortlisted NET1-dependent genes included STAT1, TSPAN1, TGFBi and CCL5 all of which were downregulatd upon NET1 downregulation. Shortlisted LPA-dependent genes included EGFR and PPARD where EGFR was upregulated and PPARD was downregulated upon LPA stimulation. Shortlisted NET1 and LPA dependent genes included IGFR1 and PIP5K3. These LPA induced genes were downregulated in NET1 knockdown cells

  1. Implementing NetScaler VPX

    CERN Document Server

    Sandbu, Marius

    2014-01-01

    An easy-to-follow guide with detailed step-by step-instructions on how to implement the different key components in NetScaler, with real-world examples and sample scenarios.If you are a Citrix or network administrator who needs to implement NetScaler in your virtual environment to gain an insight on its functionality, this book is ideal for you. A basic understanding of networking and familiarity with some of the different Citrix products such as XenApp or XenDesktop is a prerequisite.

  2. Net4Care PHMR Library

    DEFF Research Database (Denmark)

    2014-01-01

    The Net4Care PHMR library contains a) A GreenCDA approach for constructing a data object representing a PHMR document: SimpleClinicalDocument, and b) A Builder which can produce a XML document representing a valid Danish PHMR (following the MedCom profile) document from the SimpleClinicalDocument......The Net4Care PHMR library contains a) A GreenCDA approach for constructing a data object representing a PHMR document: SimpleClinicalDocument, and b) A Builder which can produce a XML document representing a valid Danish PHMR (following the MedCom profile) document from the Simple...

  3. Coloured Petri Nets and the Invariant Method

    DEFF Research Database (Denmark)

    Jensen, Kurt

    1981-01-01

    processes to be described by a common subnet, without losing the ability to distinguish between them. Our generalization, called coloured Petri nets, is heavily influenced by predicate transition-nets introduced by H.J. Genrich and K. Lautenbach. Moreover our paper shows how the invariant-method, introduced...... for Petri nets by K. Lautenbach, can be generalized to coloured Petri nets....

  4. D.NET case study

    International Development Research Centre (IDRC) Digital Library (Canada)

    lremy

    The mission was defined to build, “A society where information and ... innovative ideas and projects around different themes (using ICT), and piloting them to test .... like D.Net with several projects that had moved beyond their pilot phase.

  5. Petri Nets in Cryptographic Protocols

    DEFF Research Database (Denmark)

    Crazzolara, Federico; Winskel, Glynn

    2001-01-01

    A process language for security protocols is presented together with a semantics in terms of sets of events. The denotation of process is a set of events, and as each event specifies a set of pre and postconditions, this denotation can be viewed as a Petri net. By means of an example we illustrate...

  6. Complexity metrics for workflow nets

    NARCIS (Netherlands)

    Lassen, K.B.; Aalst, van der W.M.P.

    2009-01-01

    Process modeling languages such as EPCs, BPMN, flow charts, UML activity diagrams, Petri nets, etc., are used to model business processes and to configure process-aware information systems. It is known that users have problems understanding these diagrams. In fact, even process engineers and system

  7. Reference Guide Microsoft.NET

    NARCIS (Netherlands)

    Zee M van der; Verspaij GJ; Rosbergen S; IMP; NMD

    2003-01-01

    Met behulp van het rapport kunnen ontwikkelaars, beheerders en betrokken managers bij ICT projecten meer inzicht krijgen in de .NET technologie en een goede keuze maken in de inzetbaarheid van deze technologie. Het rapport geeft de bevindingen en conclusies van een verkennende studie naar het

  8. Complexity Metrics for Workflow Nets

    DEFF Research Database (Denmark)

    Lassen, Kristian Bisgaard; van der Aalst, Wil M.P.

    2009-01-01

    Process modeling languages such as EPCs, BPMN, flow charts, UML activity diagrams, Petri nets, etc.\\ are used to model business processes and to configure process-aware information systems. It is known that users have problems understanding these diagrams. In fact, even process engineers and system...

  9. Communicating with the Net Generation

    Science.gov (United States)

    2011-03-11

    resource investment is necessary to sustain a high quality all-volunteer force. 9 Leadership Technique for the Net Generation Army Regulation 600...Generations at Work, Millenials at Work, http://www.generationsatwork. com /articles_millennials_at_work.php (accessed November 21, 2010). 31 Thomas

  10. Net Neutrality in the Netherlands

    NARCIS (Netherlands)

    van Eijk, N.

    2014-01-01

    The Netherlands is among the first countries that have put specific net neutrality standards in place. The decision to implement specific regulation was influenced by at least three factors. The first was the prevailing social and academic debate, partly due to developments in the United States. The

  11. Surgery for GEP-NETs

    DEFF Research Database (Denmark)

    Knigge, Ulrich; Hansen, Carsten Palnæs

    2012-01-01

    Surgery is the only treatment that may cure the patient with gastroentero-pancreatic (GEP) neuroendocrine tumours (NET) and neuroendocrine carcinomas (NEC) and should always be considered as first line treatment if R0/R1 resection can be achieved. The surgical and interventional procedures for GEP...

  12. Net4Care PHMR Tutorial

    DEFF Research Database (Denmark)

    Christensen, Henrik Bærbak

    Goal To demonstrate how to use the Net4Care PHMR builder module to a) Create a SimpleClinicalDocument instance and populate it with relevant administrative and medical information to form a tele medical report of a set of measurements, b) Use the provided DanishPHMRBuilder to generate a correctly...

  13. Power balance on a multibeam laser

    Science.gov (United States)

    Sampat, S.; Kelly, J. H.; Kosc, T. Z.; Rigatti, A. L.; Kwiatkowski, J.; Donaldson, W. R.; Romanofsky, M. H.; Waxer, L. J.; Dean, R.; Moshier, R.

    2018-02-01

    Inertial confinement fusion (ICF) cryogenic experiments on the 60-beam OMEGA laser have strict requirements for the laser energy delivered on target to be power balanced in order to maximize target-irradiation uniformity. For OMEGA, this quantity (power balance) is inferred from measurements of the time-integrated energy and time-resolved, spatially integrated temporal profile of each of the 60 beams at the output of the laser. The work presented here proposes a general definition of power balance as measured at the laser output and discusses the conditions that are fundamental to achieving laser power balance. Power balance necessitates equal gain across all stages of amplification, equal net losses across each amplifier stage, equal frequency conversion (from 1053 nm to 351 nm) of all 60 beams, and equal beam path lengths (beam timing). Typical OMEGA ICF laser pulse shapes consist of one or more short (100-ps) "pickets" followed by a shaped "drive" pulse of 1 to 2 ns. For these experiments, power balance is assessed for the pickets and the drive independently, with the ultimate goal of achieving root-mean-square (rms) imbalance across all 60 beams of less than 2% rms on both. This work presents a comprehensive summary of laser shot campaigns conducted to significantly improve laser power balance from typical rms values of 4.7% and 5.2%, respectively, to the 3% level for both features along with a discussion of future work required to further reduce the rms power imbalance of the laser system.

  14. Principles of developing the bench mark net for radioecological monitoring in the territory of Byelorussia

    International Nuclear Information System (INIS)

    Doroshkevich, M.N.

    1991-01-01

    The principles of developing the radioecological monitoring bench mark net proposed include the regularity pattern of reference point setting, the bench mark net hierarchy, accounting for a land-tenure structure and the landscape and geochemical conditions of the radionuclide migration as well as a passport system and informational adequacy. The expression has been obtained for determining the location of sampling points

  15. Possibilistic Fuzzy Net Present Value Model and Application

    Directory of Open Access Journals (Sweden)

    S. S. Appadoo

    2014-01-01

    Full Text Available The cash flow values and the interest rate in the net present value (NPV model are usually specified by either crisp numbers or random variables. In this paper, we first discuss some of the recent developments in possibility theory and find closed form expressions for fuzzy possibilistic net present value (FNPV. Then, following Carlsson and Fullér (2001, we discuss some of the possibilistic moments related to FNPV model along with an illustrative numerical example. We also give a unified approach to find higher order moments of FNPV by using the moment generating function introduced by Paseka et al. (2011.

  16. .net

    Directory of Open Access Journals (Sweden)

    Le Comité de Rédaction d' EspacesTemps.net

    2002-06-01

    Full Text Available EspacesTemps lance aujourd'hui deux objets différents : un site internet et, sur ce site, Le Journal . Il s'agit donc de bien plus, et, au fond, de tout autre chose qu'un simple outil de communication destiné à informer nos lecteurs de nos parutions. Ce n'est pas non plus la « mise en ligne » de nos numéros-papier. L'internet nous donne au contraire l'occasion de réaliser, dans de meilleures conditions, ce que nous avons tenté de faire depuis quelques ...

  17. Army Net Zero Prove Out. Net Zero Energy Best Practices

    Science.gov (United States)

    2014-11-18

    recovery and cogeneration opportunities, offsetting the remaining demand with the production of renewable energy from onsite sources so that the Net...implementing energy recovery and cogeneration opportunities, and then offsetting the remaining demand with the production of renewable energy from on-site...they impact overall energy performance. The use of energy modeling in the design stage provides insights that can contribute to more effective design

  18. Net alkalinity and net acidity 2: Practical considerations

    Science.gov (United States)

    Kirby, C.S.; Cravotta, C.A.

    2005-01-01

    The pH, alkalinity, and acidity of mine drainage and associated waters can be misinterpreted because of the chemical instability of samples and possible misunderstandings of standard analytical method results. Synthetic and field samples of mine drainage having various initial pH values and concentrations of dissolved metals and alkalinity were titrated by several methods, and the results were compared to alkalinity and acidity calculated based on dissolved solutes. The pH, alkalinity, and acidity were compared between fresh, unoxidized and aged, oxidized samples. Data for Pennsylvania coal mine drainage indicates that the pH of fresh samples was predominantly acidic (pH 2.5-4) or near neutral (pH 6-7); ??? 25% of the samples had pH values between 5 and 6. Following oxidation, no samples had pH values between 5 and 6. The Standard Method Alkalinity titration is constrained to yield values >0. Most calculated and measured alkalinities for samples with positive alkalinities were in close agreement. However, for low-pH samples, the calculated alkalinity can be negative due to negative contributions by dissolved metals that may oxidize and hydrolyze. The Standard Method hot peroxide treatment titration for acidity determination (Hot Acidity) accurately indicates the potential for pH to decrease to acidic values after complete degassing of CO2 and oxidation of Fe and Mn, and it indicates either the excess alkalinity or that required for neutralization of the sample. The Hot Acidity directly measures net acidity (= -net alkalinity). Samples that had near-neutral pH after oxidation had negative Hot Acidity; samples that had pH mine drainage treatment can lead to systems with insufficient Alkalinity to neutralize metal and H+ acidity and is not recommended. The use of net alkalinity = -Hot Acidity titration is recommended for the planning of mine drainage treatment. The use of net alkalinity = (Alkalinitymeasured - Aciditycalculated) is recommended with some cautions

  19. NucNet's growing impact on the media

    Energy Technology Data Exchange (ETDEWEB)

    Carle, Remy [Electricite de France (France)

    1995-07-01

    In the four years since the birth of NucNet there has been a gradual but radical change In the original concept of the network. In the beginning, the focus of attention was to make nuclear communicators better-informed and more efficient. What had been desperately needed for some time was an Information exchange system which would enable those communicators to do a better Job whether working proactlvely or reactively. The idea was primarily for positive nuclear news from Europe to be disseminated to people on the network so that they could pass it on to media contacts in their respective countries, as part of their regular dialogue with journalists. However, once NucNet was up-and-running a strong body of opinion emerged, arguing in favour of NucNet's most urgent, important or off-beat news - the 'A' category releases - to be sent direct to national and international news agencies. Quite rightly, it was felt that, in this way, the nuclear community could clearly demonstrate Its transparency and Its desire to Inform the public openly. At the same time, it was clear that sending to just a few national news agencies in Europe would not be enough. It was clear that NucNet would have to expand into a truly worldwide network and that, to reflect this, the main International news agencies would have to be put online as well. NucNet's growing impact on the media is a result of teamwork, and this teamwork takes different forms. It is: between the network's information suppliers and Central Office, among the Central Office staff themselves, between Central Office and the agencies, and between network members and their news media contacts. Through this continuing teamwork process, NucNet will achieve its goal of providing the media and the public with a balanced picture of nuclear energy.

  20. NucNet's growing impact on the media

    International Nuclear Information System (INIS)

    Carle, Remy

    1995-01-01

    In the four years since the birth of NucNet there has been a gradual but radical change In the original concept of the network. In the beginning, the focus of attention was to make nuclear communicators better-informed and more efficient. What had been desperately needed for some time was an Information exchange system which would enable those communicators to do a better Job whether working proactlvely or reactively. The idea was primarily for positive nuclear news from Europe to be disseminated to people on the network so that they could pass it on to media contacts in their respective countries, as part of their regular dialogue with journalists. However, once NucNet was up-and-running a strong body of opinion emerged, arguing in favour of NucNet's most urgent, important or off-beat news - the 'A' category releases - to be sent direct to national and international news agencies. Quite rightly, it was felt that, in this way, the nuclear community could clearly demonstrate Its transparency and Its desire to Inform the public openly. At the same time, it was clear that sending to just a few national news agencies in Europe would not be enough. It was clear that NucNet would have to expand into a truly worldwide network and that, to reflect this, the main International news agencies would have to be put online as well. NucNet's growing impact on the media is a result of teamwork, and this teamwork takes different forms. It is: between the network's information suppliers and Central Office, among the Central Office staff themselves, between Central Office and the agencies, and between network members and their news media contacts. Through this continuing teamwork process, NucNet will achieve its goal of providing the media and the public with a balanced picture of nuclear energy

  1. Towards new information resources for public health--from WordNet to MedicalWordNet.

    Science.gov (United States)

    Fellbaum, Christiane; Hahn, Udo; Smith, Barry

    2006-06-01

    In the last two decades, WordNet has evolved as the most comprehensive computational lexicon of general English. In this article, we discuss its potential for supporting the creation of an entirely new kind of information resource for public health, viz. MedicalWordNet. This resource is not to be conceived merely as a lexical extension of the original WordNet to medical terminology; indeed, there is already a considerable degree of overlap between WordNet and the vocabulary of medicine. Instead, we propose a new type of repository, consisting of three large collections of (1) medically relevant word forms, structured along the lines of the existing Princeton WordNet; (2) medically validated propositions, referred to here as medical facts, which will constitute what we shall call MedicalFactNet; and (3) propositions reflecting laypersons' medical beliefs, which will constitute what we shall call the MedicalBeliefNet. We introduce a methodology for setting up the MedicalWordNet. We then turn to the discussion of research challenges that have to be met to build this new type of information resource. We build a database of sentences relevant to the medical domain. The sentences are generated from WordNet via its relations as well as from medical statements broken down into elementary propositions. Two subcorpora of sentences are distinguished, MedicalBeliefNet and MedicalFactNet. The former is rated for assent by laypersons; the latter for correctness by medical experts. The sentence corpora will be valuable for a variety of applications in information retrieval as well as in research in linguistics and psychology with respect to the study of expert and non-expert beliefs and their linguistic expressions. Our work has to meet several considerable challenges. These include accounting for the distinction between medical experts and laypersons, the social issues of expert-layperson communication in different media, the linguistic aspects of encoding medical knowledge, and

  2. Les dispositifs du Net art

    OpenAIRE

    Fourmentraux, Jean-Paul

    2010-01-01

    La pratique du Net art radicalise la question du potentiel communicationnel d’un média —Internet— qui constitue tout à la fois le support technique, l’outil créatif et le dispositif social de l’œuvre. Les technologies de l’information et de la communication (TIC) placent en effet l’œuvre d’art au cœur d’une négociation socialement distribuée entre l’artiste et le public. L’article est focalisé sur cette construction collective du Net art et sur ses mises en scènes. Il montre le travail artist...

  3. Complexity Metrics for Workflow Nets

    DEFF Research Database (Denmark)

    Lassen, Kristian Bisgaard; van der Aalst, Wil M.P.

    2009-01-01

    analysts have difficulties grasping the dynamics implied by a process model. Recent empirical studies show that people make numerous errors when modeling complex business processes, e.g., about 20 percent of the EPCs in the SAP reference model have design flaws resulting in potential deadlocks, livelocks......, etc. It seems obvious that the complexity of the model contributes to design errors and a lack of understanding. It is not easy to measure complexity, however. This paper presents three complexity metrics that have been implemented in the process analysis tool ProM. The metrics are defined...... for a subclass of Petri nets named Workflow nets, but the results can easily be applied to other languages. To demonstrate the applicability of these metrics, we have applied our approach and tool to 262 relatively complex Protos models made in the context of various student projects. This allows us to validate...

  4. Energy balance and efficiency of power stations with a pulsed Tokamak reactor

    International Nuclear Information System (INIS)

    Davenport, P.A.; Mitchell, J.T.D.; Darvas, J.; Foerster, S.; Sack, B.

    1976-06-01

    The energy balance of a fusion power station based on the TOKAMAK concept is examined with the aid of a model comprising three distinct elements: the reactor, the energy converter and the reactor operation equipment. The efficiency of each element is expressed in terms of the various energy flows and the product of these efficiencies gives the net station efficiency. The analysis takes account of pulsed operation and has general applicability. Numerical values for the net station efficiency are derived from detailed estimates of the energy flows for a TOKAMAK reactor and its auxiliary equipment operating with advanced energy converters. The derivation of these estimates is given in eleven appendices. The calculated station efficiencies span ranges similar to those quoted for the current generation of fission reactors, though lower than those predicted for HTGR and LMFBR stations. Credible parameter domains for pulsed TOKAMAK operation are firmly delineated and factors inimical to improved performance are indicated. It is concluded that the net thermal efficiency of a TOKAMAK reactor power station based on present designs and using advanced thermal converters will be approximately 0.3 and is unlikely to exceed 0.33. (orig.) [de

  5. dotNet som multimediaplattform

    OpenAIRE

    Johansson, Glenn

    2008-01-01

    As the speed and complexity of computers have increased so have software and the expectations of users. Software development follows a straightforward evolution where complicated tasks are made easier by better tools; this repeats itself as those tasks in turn are automated. Software mechanics that were seen as revolutionary a decade ago are seen as obvious requirements that no multimedia application can be without. dotNet is the next step in line and makes it easier and faster to build softw...

  6. Energy performance of windows based on the net energy gain

    DEFF Research Database (Denmark)

    Svendsen, Svend; Kragh, Jesper; Laustsen, Jacob Birck

    2005-01-01

    The paper presents a new method to set up energy performance requirements and energy classes for windows of all dimensions and configurations. The net energy gain of windows is the solar gain minus the heat loss integrated over the heating season. The net energy gain can be calculated for one...... be expressed as a function of two parameters representing the energy performance and two parameters representing the geometry of the window. The two energy performance parameters are the net energy gain per area of the glazing unit and the sum of the heat losses through the frame and the assembly per length...... of the frame. The two geometry numbers are the area of the glazing unit relative to the window area and the length of the frame profiles relative to the window area. Requirements and classes for the energy performance of the window can be given by assigning values to the two energy performance parameters...

  7. NET model coil test possibilities

    International Nuclear Information System (INIS)

    Erb, J.; Gruenhagen, A.; Herz, W.; Jentzsch, K.; Komarek, P.; Lotz, E.; Malang, S.; Maurer, W.; Noether, G.; Ulbricht, A.; Vogt, A.; Zahn, G.; Horvath, I.; Kwasnitza, K.; Marinucci, C.; Pasztor, G.; Sborchia, C.; Weymuth, P.; Peters, A.; Roeterdink, A.

    1987-11-01

    A single full size coil for NET/INTOR represents an investment of the order of 40 MUC (Million Unit Costs). Before such an amount of money or even more for the 16 TF coils is invested as much risks as possible must be eliminated by a comprehensive development programme. In the course of such a programme a coil technology verification test should finally prove the feasibility of NET/INTOR TF coils. This study report is almost exclusively dealing with such a verification test by model coil testing. These coils will be built out of two Nb 3 Sn-conductors based on two concepts already under development and investigation. Two possible coil arrangements are discussed: A cluster facility, where two model coils out of the two Nb 3 TF-conductors are used, and the already tested LCT-coils producing a background field. A solenoid arrangement, where in addition to the two TF model coils another model coil out of a PF-conductor for the central PF-coils of NET/INTOR is used instead of LCT background coils. Technical advantages and disadvantages are worked out in order to compare and judge both facilities. Costs estimates and the time schedules broaden the base for a decision about the realisation of such a facility. (orig.) [de

  8. NET-2 Network Analysis Program

    International Nuclear Information System (INIS)

    Malmberg, A.F.

    1974-01-01

    The NET-2 Network Analysis Program is a general purpose digital computer program which solves the nonlinear time domain response and the linearized small signal frequency domain response of an arbitrary network of interconnected components. NET-2 is capable of handling a variety of components and has been applied to problems in several engineering fields, including electronic circuit design and analysis, missile flight simulation, control systems, heat flow, fluid flow, mechanical systems, structural dynamics, digital logic, communications network design, solid state device physics, fluidic systems, and nuclear vulnerability due to blast, thermal, gamma radiation, neutron damage, and EMP effects. Network components may be selected from a repertoire of built-in models or they may be constructed by the user through appropriate combinations of mathematical, empirical, and topological functions. Higher-level components may be defined by subnetworks composed of any combination of user-defined components and built-in models. The program provides a modeling capability to represent and intermix system components on many levels, e.g., from hole and electron spatial charge distributions in solid state devices through discrete and integrated electronic components to functional system blocks. NET-2 is capable of simultaneous computation in both the time and frequency domain, and has statistical and optimization capability. Network topology may be controlled as a function of the network solution. (U.S.)

  9. Offshore wind energy : balancing risk and reward

    International Nuclear Information System (INIS)

    Nerland, C.

    2010-01-01

    Offshore wind energy developments are expected to increase as the demand for renewable energy sources grows. This poster presentation described a method of balancing risk and reward in offshore wind energy projects. The method was based on risk assessment strategies used by the oil and gas industry. The dedicated framework considered schedules; budgets; performance; and operating and maintenance costs. A value chain assessment method was used to optimize the balance between risk and reward by evaluating uncertainties and risk related to each project element and its relationship to other elements within an integrated dynamic model designed to determine the net present value of a project. The decision-making criteria included the RISKEX risk expenditure strategy designed to consider the balance between risk exposure, capital expenditures, and operational expenditures in relation to the statistical cost of unplanned repairs, and lost production capacity. A case study of a large offshore wind farm was used to demonstrate the method. tabs., figs.

  10. Bank stress testing under different balance sheet assumptions

    OpenAIRE

    Busch, Ramona; Drescher, Christian; Memmel, Christoph

    2017-01-01

    Using unique supervisory survey data on the impact of a hypothetical interest rate shock on German banks, we analyse price and quantity effects on banks' net interest margin components under different balance sheet assumptions. In the first year, the cross-sectional variation of banks' simulated price effect is nearly eight times as large as the one of the simulated quantity effect. After five years, however, the importance of both effects converges. Large banks adjust their balance sheets mo...

  11. Development of Network Interface Cards for TRIDAQ systems with the NaNet framework

    International Nuclear Information System (INIS)

    Ammendola, R.; Biagioni, A.; Cretaro, P.; Frezza, O.; Cicero, F. Lo; Lonardo, A.; Martinelli, M.; Paolucci, P.S.; Pastorelli, E.; Simula, F.; Valente, P.; Vicini, P.; Lorenzo, S. Di; Piandani, R.; Pontisso, L.; Sozzi, M.; Fiorini, M.; Neri, I.; Lamanna, G.; Rossetti, D.

    2017-01-01

    NaNet is a framework for the development of FPGA-based PCI Express (PCIe) Network Interface Cards (NICs) with real-time data transport architecture that can be effectively employed in TRIDAQ systems. Key features of the architecture are the flexibility in the configuration of the number and kind of the I/O channels, the hardware offloading of the network protocol stack, the stream processing capability, and the zero-copy CPU and GPU Remote Direct Memory Access (RDMA). Three NIC designs have been developed with the NaNet framework: NaNet-1 and NaNet-10 for the CERN NA62 low level trigger and NaNet 3 for the KM3NeT-IT underwater neutrino telescope DAQ system. We will focus our description on the NaNet-10 design, as it is the most complete of the three in terms of capabilities and integrated IPs of the framework.

  12. The Uniframe .Net Web Service Discovery Service

    National Research Council Canada - National Science Library

    Berbeco, Robert W

    2003-01-01

    Microsoft .NET allows the creation of distributed systems in a seamless manner Within NET small, discrete applications, referred to as Web services, are utilized to connect to each other or larger applications...

  13. Long Term RadNet Quality Data

    Data.gov (United States)

    U.S. Environmental Protection Agency — This RadNet Quality Data Asset includes all data since initiation and when ERAMS was expanded to become RadNet, name changed to reflect new mission. This includes...

  14. Special Section on Coloured Petri Nets

    DEFF Research Database (Denmark)

    1998-01-01

    Special section on coloured Petri nets, their basic concepts, analysis methods, tool support and industrial applications.......Special section on coloured Petri nets, their basic concepts, analysis methods, tool support and industrial applications....

  15. EQUILIBRIUM ANALYSIS OF FINANCIAL COMPANY BASED ON INFORMATION PROVIDED BY THE BALANCE SHEET

    Directory of Open Access Journals (Sweden)

    Ștefăniță ȘUȘU

    2014-06-01

    Full Text Available This article highlights the importance of indicators (as net working capital, working capital requirements and net cash by means of which it is considered in the context of financial balances capitalization information released by the balance sheet of an entity tourist profile. Theoretical concepts presented in a logical sequence are combined with the practical example transposed Turism Covasna company. The results of the analysis are interpreted while trying to formulate solutions to the economic and financial viability of the entity.

  16. The balance-of-payments constraint:from balanced trade to sustainable debt

    Directory of Open Access Journals (Sweden)

    Nelson H. Barbosa-Filho

    2001-12-01

    Full Text Available This paper extends the balance-of-payments constraint on growth known as Thirlwall's law to incorporate unbalanced trade and debt accumulation. Assuming that small open economies face a liquidity constraint, the text shows the growth and real-exchange-rate policy rules consistent with a stable ratio of net exports to income. Given such rules, the text shows how the trade balance of a small open economy is residually determined by the ratio of foreign debt to income allowed by international conditions.

  17. NetBeans IDE 8 cookbook

    CERN Document Server

    Salter, David

    2014-01-01

    If you're a Java developer of any level using NetBeans and want to learn how to get the most out of NetBeans, then this book is for you. Learning how to utilize NetBeans will provide a firm foundation for your Java application development.

  18. History-dependent stochastic Petri nets

    NARCIS (Netherlands)

    Schonenberg, H.; Sidorova, N.; Aalst, van der W.M.P.; Hee, van K.M.; Pnueli, A.; Virbitskaite, I.; Voronkov, A.

    2010-01-01

    Stochastic Petri Nets are a useful and well-known tool for performance analysis. However, an implicit assumption in the different types of Stochastic Petri Nets is the Markov property. It is assumed that a choice in the Petri net only depends on the current state and not on earlier choices. For many

  19. Putting Petri nets to work in Industry

    NARCIS (Netherlands)

    Aalst, van der W.M.P.

    1994-01-01

    Petri nets exist for over 30 years. Especially in the last decade Petri nets have been put into practive extensively. Thanks to several useful extensions and the availability of computer tools, Petri nets have become a mature tool for modelling and analysing industrial systems. This paper describes

  20. Aplicació Microsoft .Net : Hotel Spa

    OpenAIRE

    Marquès Palmer, Jordi

    2010-01-01

    Desenvolupament d'una aplicació amb Microsoft .NET, WCF, WPF, Linq2SQL, d'un Hotel Spa. Desarrollo de una aplicación con Microsoft .NET, WCF, WPF, Linq2SQL, de un Hotel Spa. Application development using Microsoft .NET, WCF, WPF, Linq2SQL, for a Spa Hotel.

  1. Delta Semantics Defined By Petri Nets

    DEFF Research Database (Denmark)

    Jensen, Kurt; Kyng, Morten; Madsen, Ole Lehrmann

    and the possibility of using predicates to specify state changes. In this paper a formal semantics for Delta is defined and analysed using Petri nets. Petri nets was chosen because the ideas behind Petri nets and Delta concide on several points. A number of proposals for changes in Delta, which resulted from...

  2. The K-NET - A year after

    International Nuclear Information System (INIS)

    Kinoshita, S.; Ohtani, K.; Katayama, T.

    2001-01-01

    We started to release the K-NET strong-motion data from June 1996 and about one year passed. In this article, we report the development of K-NET and some applications using the K-NET information released on the Internet. (author)

  3. 47 CFR 65.500 - Net income.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Net income. 65.500 Section 65.500... OF RETURN PRESCRIPTION PROCEDURES AND METHODOLOGIES Interexchange Carriers § 65.500 Net income. The net income methodology specified in § 65.450 shall be utilized by all interexchange carriers that are...

  4. 47 CFR 65.450 - Net income.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Net income. 65.450 Section 65.450... OF RETURN PRESCRIPTION PROCEDURES AND METHODOLOGIES Exchange Carriers § 65.450 Net income. (a) Net income shall consist of all revenues derived from the provision of interstate telecommunications services...

  5. INMARSAT-C SafetyNET

    Science.gov (United States)

    Tsunamis 406 EPIRB's National Weather Service Marine Forecasts INMARSAT-C SafetyNET Marine Forecast Offices greater danger near shore or any shallow waters? NATIONAL WEATHER SERVICE PRODUCTS VIA INMARSAT-C SafetyNET Inmarsat-C SafetyNET is an internationally adopted, automated satellite system for promulgating

  6. From deficit to surplus: An econometric analysis of US trade balance in forest products

    Science.gov (United States)

    Daowei Zhang; Ying Lin; Jeffrey P. Prestemon

    2017-01-01

    Although the US trade deficit has persisted since 1975, the country changed in 2009 from a net importer to a net exporter of forest products, emerging as the world's largest exporter of forest products. Drawing on recent data, we model the real dollar value of US exports, imports, and the trade balance in forest products to identify factors likely to explain this...

  7. Balanced Scorecard voor inkoop

    NARCIS (Netherlands)

    van der Honing, R.; Schotanus, Fredo

    2003-01-01

    Een Balanced Scorecard kan ontwikkeld worden voor de hele organisatie, maar ook voor onderdelen daarvan. In dit artikel wordt ingegaan op de ontwikkeling van een Balanced Scorecard voor de inkoopafdeling

  8. The Balanced Company

    DEFF Research Database (Denmark)

    through control or trust. Human resource specialists need to make balanced decisions about how to design tasks and jobs in order to make them attractive as well as motivating. Marketers need to make balanced decisions about how to market products in the light of what is now important in consumers...... in their environments. Communication specialists need to make balanced decisions which take the different value systems and assumptions of stakeholders into consideration. Change specialists need to balance the need for continuity and change. Managers need to make balanced decisions about whether to achieve goals...... the creation and recreation of balanced relationships. Chapters in The Balanced Company ask and provide answers to questions about corporately responsible and ethically driven balanced decision making, such as: • How can a company and its stakeholders identify what should be taken into consideration - What...

  9. Chance for balance: Chance for balance

    OpenAIRE

    Sævild, Katariina; Skov Sørensen, Katrine; Kildahl Lauritsen, Louise; Fuglsang, Sofie Olivia; Arnbjerg, Stine Høegh

    2015-01-01

    This project investigates how (im) balance between family and career influences Danish women's desire to have children. In order to answer this question, we have chosen to use qualitative method and our analysis is based on two semi-structured research interviews with two chosen women. Thus these women’s definition of balance and their view on children define the project. We have chosen to use of work-life balance theories, Thomas Hoejrup’s lifeform-analysis and Anthony Giddens’ theories of s...

  10. NET 40 Generics Beginner's Guide

    CERN Document Server

    Mukherjee, Sudipta

    2012-01-01

    This is a concise, practical guide that will help you learn Generics in .NET, with lots of real world and fun-to-build examples and clear explanations. It is packed with screenshots to aid your understanding of the process. This book is aimed at beginners in Generics. It assumes some working knowledge of C# , but it isn't mandatory. The following would get the most use out of the book: Newbie C# developers struggling with Generics. Experienced C++ and Java Programmers who are migrating to C# and looking for an alternative to other generic frameworks like STL and JCF would find this book handy.

  11. Climatic Forecasting of Net Infiltration at Yucca Mountain Using Analogue Meteorological Data

    International Nuclear Information System (INIS)

    B. Faybishenko

    2006-01-01

    At Yucca Mountain, Nevada, future changes in climatic conditions will most likely alter net infiltration, or the drainage below the bottom of the evapotranspiration zone within the soil profile or flow across the interface between soil and the densely welded part of the Tiva Canyon Tuff. The objectives of this paper are to: (a) develop a semi-empirical model and forecast average net infiltration rates, using the limited meteorological data from analogue meteorological stations, for interglacial (present day), and future monsoon, glacial transition, and glacial climates over the Yucca Mountain region, and (b) corroborate the computed net-infiltration rates by comparing them with the empirically and numerically determined groundwater recharge and percolation rates through the unsaturated zone from published data. In this paper, the author presents an approach for calculations of net infiltration, aridity, and precipitation-effectiveness indices, using a modified Budyko's water-balance model, with reference-surface potential evapotranspiration determined from the radiation-based Penman (1948) formula. Results of calculations show that net infiltration rates are expected to generally increase from the present-day climate to monsoon climate, to glacial transition climate, and then to the glacial climate. The forecasting results indicate the overlap between the ranges of net infiltration for different climates. For example, the mean glacial net-infiltration rate corresponds to the upper-bound glacial transition net infiltration, and the lower-bound glacial net infiltration corresponds to the glacial transition mean net infiltration. Forecasting of net infiltration for different climate states is subject to numerous uncertainties-associated with selecting climate analogue sites, using relatively short analogue meteorological records, neglecting the effects of vegetation and surface runoff and runon on a local scale, as well as possible anthropogenic climate changes

  12. Gap filling strategies for defensible annual sums of net ecosystem exchange

    NARCIS (Netherlands)

    Falge, E.; Baldocchi, D.; Olson, R.; Anthoni, P.; Aubinet, M.; Bernhofer, C.; Burba, G.; Ceulemans, R.; Clement, R.; Dolman, H.; Granier, A.; Gross, P.; Grünwald, T.; Hollinger, D.; Jensen, N.O.; Katul, G.; Keronen, P.; Kowalski, A.; Lai, C.T.; Law, B.E.; Meyers, T.; Moncrieff, J.; Moors, E.J.; Munger, J.W.; Pilegaard, K.; Rebmann, C.; Suyker, A.; Tenhunen, J.; Tu, K.

    2001-01-01

    Heightened awareness of global change issues within both science and political communities has increased interest in using the global network of eddy covariance flux towers to more fully understand the impacts of natural and anthropogenic phenomena on the global carbon balance. Comparisons of net

  13. 16 CFR 801.11 - Annual net sales and total assets.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Annual net sales and total assets. 801.11 Section 801.11 Commercial Practices FEDERAL TRADE COMMISSION RULES, REGULATIONS, STATEMENTS AND... person; and (2) The total assets of a person shall be as stated on the last regularly prepared balance...

  14. Relationships between net primary productivity and forest stand age in U.S. forests

    Science.gov (United States)

    Liming He; Jing M. Chen; Yude Pan; Richard Birdsey; Jens. Kattge

    2012-01-01

    Net primary productivity (NPP) is a key flux in the terrestrial ecosystem carbon balance, as it summarizes the autotrophic input into the system. Forest NPP varies predictably with stand age, and quantitative information on the NPP-age relationship for different regions and forest types is therefore fundamentally important for forest carbon cycle modeling. We used four...

  15. Editorial Seminar.net Issue 3 Vol. 6

    Directory of Open Access Journals (Sweden)

    Yngve Nordkvelle

    2010-11-01

    Full Text Available Seminar.net reached 100 000 unique visitors in October 2010 after nearly six years on the web. Since its inception, a total number of 64 articles have been published, and the site has been visited 3000 times each month at its most. A journal needs to publish good articles. Judging by the increasing number of readers, the readers seem to find our articles to be relevant, readable and contributing to the global discourse. The e-journal format offers opportunities to employ the media to its full potential. A unique feature of the e-journal is to communicate in other media than textual. Seminar.net has for a long time been alone on the academic marked in the field of presenting an abstract of the paper in video format. The assumption is that a short introduction presented on a video makes the reader more interested and that he/she reads the paper with more enthusiasm. On the other hand, journal readers are conservative, and often fail to appreciate the value of visual communication other than the textual. It will be a challenge to continue to develop the e-journal genre in light of the need to balance reader conservatism with exploring the opportunities offered by multimedia-publishing.The second feature of dealing with an e-journal is to offer an alternative voice. Critique and reappraisal in social science is highly valued and seen as a vital condition for renewal and progress in the academic community. Paper journals are often seen as conservative and in favour of “normal” science in Thomas Kuhn’s terms. The “gatekeepers” are piled up in their editorial boards. E-journals subscribing to an Open Access Policy have a reputation of the opposite. E-journals have made it easier to express critical ideas and represent marginalised viewpoints in main stream science.Seminar.net has readers in 150 countries, from all continents, and with a majority of readers from USA and India, but has also significant number of readers from England, Australia

  16. Get the Balance Right.

    Science.gov (United States)

    Haddock, Rebecca Jaurigue

    Today work goes on 24 hours a day, 7 days a week, and is about acceleration and access. Workers need balance more than ever. In fact, recent college graduates value work/life balance as their key factor in selecting employers. This paper, written for career counselors, defines balance as encompassing emotional, spiritual, physical, and…

  17. CellNet: Network Biology Applied to Stem Cell Engineering

    Science.gov (United States)

    Cahan, Patrick; Li, Hu; Morris, Samantha A.; da Rocha, Edroaldo Lummertz; Daley, George Q.; Collins, James J.

    2014-01-01

    SUMMARY Somatic cell reprogramming, directed differentiation of pluripotent stem cells, and direct conversions between differentiated cell lineages represent powerful approaches to engineer cells for research and regenerative medicine. We have developed CellNet, a network biology platform that more accurately assesses the fidelity of cellular engineering than existing methodologies and generates hypotheses for improving cell derivations. Analyzing expression data from 56 published reports, we found that cells derived via directed differentiation more closely resemble their in vivo counterparts than products of direct conversion, as reflected by the establishment of target cell-type gene regulatory networks (GRNs). Furthermore, we discovered that directly converted cells fail to adequately silence expression programs of the starting population, and that the establishment of unintended GRNs is common to virtually every cellular engineering paradigm. CellNet provides a platform for quantifying how closely engineered cell populations resemble their target cell type and a rational strategy to guide enhanced cellular engineering. PMID:25126793

  18. APROACHING THE ECONOMIC DIMENSION OF SUSTAINABLE DEVELOPMENT FROM A FINANCIAL PERSPECTIVE: A CASE STUDY REGARDING CASH - FLOW ANALYSIS AND THE RELATIONSIPS BETWEEN CASH - FLOW AND NET INCOME

    Directory of Open Access Journals (Sweden)

    Diana Elena Vasiu

    2014-10-01

    Full Text Available Europe 2020, a strategy for smart, sustainable and inclusive growth stresses the necessity of smart, sustainable and inclusive growth. The objectives of a sustainable economic development include sustaining economic growth, maximizing private profits and expanding markets. Considering this, economic development must based on facts, not on papers. Therefore, considering the economic dimension of sustainable development, it is important to establish if Romanian companies listed and traded on Bucharest Stock Exchange are able to obtain profit while cash is withdrawn. Even if reported in the income statement, net profit is not simultaneously charged due to accrual accounting that makes the balance sheet provide a static picture of the financial position, while the cash flow statement provides a dynamic picture of it. Therefore, the financial performance analysis based on classical indicators of performance must be accompanied by the analysis of treasury, namely of the cash flow, which provides a comprehensive assessment possibility of the financial performance, flexibility and adaptability of the economic entity, in the context of a highly competitive and often unstable environment. A positive net flows is a confirmation of the economic success of the company representing the concrete expression of the net profit and other pecuniary accumulations, interpreted as the real self-financing investment capacity, which would lead to the real asset growth and thus to the increase of the owners' wealth.

  19. Vascular endothelial growth factor receptor-3 is a novel target to improve net ultrafiltration in methylglyoxal-induced peritoneal injury.

    Science.gov (United States)

    Terabayashi, Takeshi; Ito, Yasuhiko; Mizuno, Masashi; Suzuki, Yasuhiro; Kinashi, Hiroshi; Sakata, Fumiko; Tomita, Takako; Iguchi, Daiki; Tawada, Mitsuhiro; Nishio, Ryosuke; Maruyama, Shoichi; Imai, Enyu; Matsuo, Seiichi; Takei, Yoshifumi

    2015-09-01

    Appropriate fluid balance is important for good clinical outcomes and survival in patients on peritoneal dialysis. We recently reported that lymphangiogenesis associated with fibrosis developed in the peritoneal cavity via the transforming growth factor-β1-vascular endothelial growth factor-C (VEGF-C) pathway. We investigated whether VEGF receptor-3 (VEGFR-3), the receptor for VEGF-C and -D, might be a new target to improve net ultrafiltration by using adenovirus-expressing soluble VEGFR-3 (Adeno-sVEGFR-3) in rodent models of peritoneal injury induced by methylglyoxal (MGO). We demonstrated that lymphangiogenesis developed in these MGO models, especially in the diaphragm, indicating that lymphangiogenesis is a common feature in the peritoneal cavity with inflammation and fibrosis. In MGO models, VEGF-D was significantly increased in the diaphragm; however, VEGF-C was not significantly upregulated. Adeno-sVEGFR-3, which was detected on day 50 after administration via tail vein injections, successfully suppressed lymphangiogenesis in the diaphragm and parietal peritoneum in mouse MGO models without significant effects on fibrosis, inflammation, or neoangiogenesis. Drained volume in the peritoneal equilibration test using a 7.5% icodextrin peritoneal dialysis solution (the 7.5% icodextrin peritoneal equilibration test) was improved by Adeno-sVEGFR-3 on day 22 (Ptarget to improve net ultrafiltration by suppressing lymphatic absorption and that the 7.5% icodextrin peritoneal equilibration test is useful for estimation of lymphatic absorption.

  20. Passive designs and renewable energy systems optimization of a net zero energy building in Embrun/France

    Science.gov (United States)

    Harkouss, F.; Biwole, P. H.; Fardoun, F.

    2018-05-01

    Buildings’ optimization is a smart method to inspect the available design choices starting from passive strategies, to energy efficient systems and finally towards the adequate renewable energy system to be implemented. This paper outlines the methodology and the cost-effectiveness potential for optimizing the design of net-zero energy building in a French city; Embrun. The non-dominated sorting genetic algorithm is chosen in order to minimize thermal, electrical demands and life cycle cost while reaching the net zero energy balance; and thus getting the Pareto-front. Elimination and Choice Expressing the Reality decision making method is applied to the Pareto-front so as to obtain one optimal solution. A wide range of energy efficiency measures are investigated, besides solar energy systems are employed to produce required electricity and hot water for domestic purposes. The results indicate that the appropriate selection of the passive parameters is very important and critical in reducing the building energy consumption. The optimum design parameters yield to a decrease of building’s thermal loads and life cycle cost by 32.96% and 14.47% respectively.

  1. A quantitative assessment of the determinants of the net energy value of biofuels

    International Nuclear Information System (INIS)

    Bureau, Jean-Christophe; Disdier, Anne-Celia; Gauroy, Christine; Treguer, David

    2010-01-01

    Many studies have investigated the net energy balance of biofuel products (in terms of savings on fossil fuels) and assessed the reductions in greenhouse gas emissions from substituting biofuels for fossil fuel. These studies provide very different results, with net balance ranging from highly positive to negative. Our study analyses a large sample of these studies by retrieving the main parameters used and converting them into units of measurement that are comparable. This information is used to unravel the main determinants of the differences in net energy value across studies. Our approach relies on descriptive statistics and econometric estimates based on a meta-analysis methodology. Our results suggest that the large variability across studies can be explained by the degree to which particular inputs (i.e. nitrogen, farm labor) are controlled for, and the way fossil energy consumption is allocated to the various co-products.

  2. Towards a Standard for Modular Petri Nets

    DEFF Research Database (Denmark)

    Kindler, Ekkart; Petrucci, Laure

    2009-01-01

    concepts could or should be subject to import and export in high-level Petri nets. In this paper, we formalise a minimal version of modular high-level Petri nets, which is based on the concepts of modular PNML. This shows that modular PNML can be formalised once a specific version of Petri net is fixed....... Moreover, we present and discuss some more advanced features of modular Petri nets that could be included in the standard. This way, we provide a formal foundation and a basis for a discussion of features to be included in the upcoming standard of a module concept for Petri nets in general and for high-level...

  3. Breaking the excitation-inhibition balance makes the cortical network’s space-time dynamics distinguish simple visual scenes

    DEFF Research Database (Denmark)

    Roland, Per E.; Bonde, Lars H.; Forsberg, Lars E.

    2017-01-01

    Brain dynamics are often taken to be temporal dynamics of spiking and membrane potentials in a balanced network. Almost all evidence for a balanced network comes from recordings of cell bodies of few single neurons, neglecting more than 99% of the cortical network. We examined the space......-time dynamics of excitation and inhibition simultaneously in dendrites and axons over four visual areas of ferrets exposed to visual scenes with stationary and moving objects. The visual stimuli broke the tight balance between excitation and inhibition such that the network exhibited longer episodes of net...... excitation subsequently balanced by net inhibition, in contrast to a balanced network. Locally in all four areas the amount of net inhibition matched the amount of net excitation with a delay of 125 ms. The space-time dynamics of excitation-inhibition evolved to reduce the complexity of neuron interactions...

  4. Properties of Distributed Timed-Arc Petri Nets

    DEFF Research Database (Denmark)

    Nielsen, M.; Sassone, V.; Srba, J.

    2001-01-01

    In [12] we started a research on a distributed-timed extension of Petri nets where time parameters are associated with tokens and arcs carry constraints that qualify the age of tokens required for enabling. This formalism enables to model e.g. hardware architectures like GALS. We give a formal...... definition of process semantics for our model and investigate several properties of local versus global timing: expressiveness, reachability and coverability....

  5. Net metering in British Columbia : white paper

    International Nuclear Information System (INIS)

    Berry, T.

    2003-01-01

    Net metering was described as being the reverse registration of an electricity customer's revenue meter when interconnected with a utility's grid. It is a provincial policy designed to encourage small-distributed renewable power generation such as micro-hydro, solar energy, fuel cells, and larger-scale wind energy. It was noted that interconnection standards for small generation is an important issue that must be addressed. The British Columbia Utilities Commission has asked BC Hydro to prepare a report on the merits of net metering in order to support consultations on a potential net metering tariff application by the utility. This report provides information on net metering with reference to experience in other jurisdictions with net metering, and the possible costs and benefits associated with net metering from both a utility and consumer perspective. Some of the barriers and policy considerations for successful implementation of net metering were also discussed. refs., tabs., figs

  6. Salt balance, fresh water residence time and budget for non ...

    African Journals Online (AJOL)

    Water and salt budgets suggest that in order to balance the inflow and outflow of water at Makoba bay, there is net flux of water from the bay to the open ocean during wet season. Residual salt fluxes between the bay and the open ocean indicate advective salt export. Exchange of water between the bay with the open ocean ...

  7. bathymetric survey and estimation of the water balance of lake

    African Journals Online (AJOL)

    Preferred Customer

    The average annual open water evaporation, estimated from Colorado Class-A Pan records and Penman modified method is 23.49 million cubic .... Therefore, the ∆S term in equation 2 can be replaced by the net unmeasured ground .... appears that the steady-state water balance is reasonable. Because, the residual value ...

  8. DYMAC digital electronic balance

    International Nuclear Information System (INIS)

    Stephens, M.M.

    1980-06-01

    The Dynamic Materials Accountability (DYMAC) System at LASL integrates nondestructive assay (NDA) instruments with interactive data-processing equipment to provide near-real-time accountability of the nuclear material in the LASL Plutonium Processing Facility. The most widely used NDA instrument in the system is the DYMAC digital electronic balance. The DYMAC balance is a commercial instrument that has been modified at LASL for weighing material in gloveboxes and for transmitting the weight data directly to a central computer. This manual describes the balance components, details the LASL modifications, reviews a DYMAC measurement control program that monitors balance performance, and provides instructions for balance operation and maintenance

  9. Pro-Nets versus No-Nets: Differences in Urban Older Adults' Predilections for Internet Use

    Science.gov (United States)

    Cresci, M. Kay; Yarandi, Hossein N.; Morrell, Roger W.

    2010-01-01

    Enthusiasm for information technology (IT) is growing among older adults. Many older adults enjoy IT and the Internet (Pro-Nets), but others have no desire to use it (No-Nets). This study found that Pro-Nets and No-Nets were different on a number of variables that might predict IT use. No-Nets were older, had less education and income, were…

  10. Natural calcium isotonic composition of urine as a marker of bone mineral balance

    Science.gov (United States)

    Skulan, J.; Bullen, T.; Anbar, A.D.; Puzas, J.E.; Shackelford, L.; LeBlanc, A.; Smith, S.M.

    2007-01-01

    Background: We investigated whether changes in the natural isotopic composition of calcium in human urine track changes in net bone mineral balance, as predicted by a model of calcium isotopic behavior in vertebrates. If so, isotopic analysis of natural urine or blood calcium could be used to monitor short-term changes in bone mineral balance that cannot be detected with other techniques. Methods: Calcium isotopic compositions are expressed as ??44Ca, or the difference in parts per thousand between the 44Ca/40Ca of a sample and the 44Ca/ 40Ca of a standard reference material. ??44Ca was measured in urine samples from 10 persons who participated in a study of the effectiveness of countermeasures to bone loss in spaceflight, in which 17 weeks of bed rest was used to induce bone loss. Study participants were assigned to 1 of 3 treatment groups: controls received no treatment, one treatment group received alendronate, and another group performed resistive exercise. Measurements were made on urine samples collected before, at 2 or 3 points during, and after bed rest. Results: Urine ??44Ca values during bed rest were lower in controls than in individuals treated with alendronate (P bone mineral density data. Conclusion: Results confirm the predicted relationship between bone mineral balance and calcium isotopes, suggesting that calcium isotopic analysis of urine might be refined into a clinical and research tool. ?? 2007 American Association for Clinical Chemistry.

  11. Tropical forests are a net carbon source based on aboveground measurements of gain and loss

    Science.gov (United States)

    Baccini, A.; Walker, W.; Carvalho, L.; Farina, M.; Sulla-Menashe, D.; Houghton, R. A.

    2017-10-01

    The carbon balance of tropical ecosystems remains uncertain, with top-down atmospheric studies suggesting an overall sink and bottom-up ecological approaches indicating a modest net source. Here we use 12 years (2003 to 2014) of MODIS pantropical satellite data to quantify net annual changes in the aboveground carbon density of tropical woody live vegetation, providing direct, measurement-based evidence that the world’s tropical forests are a net carbon source of 425.2 ± 92.0 teragrams of carbon per year (Tg C year-1). This net release of carbon consists of losses of 861.7 ± 80.2 Tg C year-1 and gains of 436.5 ± 31.0 Tg C year-1. Gains result from forest growth; losses result from deforestation and from reductions in carbon density within standing forests (degradation or disturbance), with the latter accounting for 68.9% of overall losses.

  12. Balancing energy flexibilities through aggregation

    DEFF Research Database (Denmark)

    Valsomatzis, Emmanouil; Hose, Katja; Pedersen, Torben Bach

    2014-01-01

    One of the main goals of recent developments in the Smart Grid area is to increase the use of renewable energy sources. These sources are characterized by energy fluctuations that might lead to energy imbalances and congestions in the electricity grid. Exploiting inherent flexibilities, which exist...... in both energy production and consumption, is the key to solving these problems. Flexibilities can be expressed as flex-offers, which due to their high number need to be aggregated to reduce the complexity of energy scheduling. In this paper, we discuss balance aggregation techniques that already during...... aggregation aim at balancing flexibilities in production and consumption to reduce the probability of congestions and reduce the complexity of scheduling. We present results of our extensive experiments....

  13. Bound states in string nets

    Science.gov (United States)

    Schulz, Marc Daniel; Dusuel, Sébastien; Vidal, Julien

    2016-11-01

    We discuss the emergence of bound states in the low-energy spectrum of the string-net Hamiltonian in the presence of a string tension. In the ladder geometry, we show that a single bound state arises either for a finite tension or in the zero-tension limit depending on the theory considered. In the latter case, we perturbatively compute the binding energy as a function of the total quantum dimension. We also address this issue in the honeycomb lattice where the number of bound states in the topological phase depends on the total quantum dimension. Finally, the internal structure of these bound states is analyzed in the zero-tension limit.

  14. -Net Approach to Sensor -Coverage

    Directory of Open Access Journals (Sweden)

    Fusco Giordano

    2010-01-01

    Full Text Available Wireless sensors rely on battery power, and in many applications it is difficult or prohibitive to replace them. Hence, in order to prolongate the system's lifetime, some sensors can be kept inactive while others perform all the tasks. In this paper, we study the -coverage problem of activating the minimum number of sensors to ensure that every point in the area is covered by at least sensors. This ensures higher fault tolerance, robustness, and improves many operations, among which position detection and intrusion detection. The -coverage problem is trivially NP-complete, and hence we can only provide approximation algorithms. In this paper, we present an algorithm based on an extension of the classical -net technique. This method gives an -approximation, where is the number of sensors in an optimal solution. We do not make any particular assumption on the shape of the areas covered by each sensor, besides that they must be closed, connected, and without holes.

  15. The Net Reclassification Index (NRI)

    DEFF Research Database (Denmark)

    Pepe, Margaret S.; Fan, Jing; Feng, Ziding

    2015-01-01

    The Net Reclassification Index (NRI) is a very popular measure for evaluating the improvement in prediction performance gained by adding a marker to a set of baseline predictors. However, the statistical properties of this novel measure have not been explored in depth. We demonstrate the alarming...... result that the NRI statistic calculated on a large test dataset using risk models derived from a training set is likely to be positive even when the new marker has no predictive information. A related theoretical example is provided in which an incorrect risk function that includes an uninformative...... marker is proven to erroneously yield a positive NRI. Some insight into this phenomenon is provided. Since large values for the NRI statistic may simply be due to use of poorly fitting risk models, we suggest caution in using the NRI as the basis for marker evaluation. Other measures of prediction...

  16. NETS - Danish participation. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Alsen, S. (Grontmij - Carl Bro, Glostrup (Denmark)); Theel, C. (Baltic Sea Solutions, Holeby (Denmark))

    2008-12-15

    Within the NICe-funded project 'Nordic Environmental Technology Solutions (NETS)' a new type of networking at the Nordic level was organized in order to jointly exploit the rapidly growing market potential in the environmental technology sector. The project aimed at increased and professionalized commercialization of Nordic Cleantech in energy and water business segments through 1) closer cooperation and joint marketing activities, 2) a website, 3) cleantech product information via brochures and publications 4) and participating in relevant trade fairs and other industry events. Facilitating business-to-business activities was another core task for the NETS project partners from Norway, Sweden, Finland and Denmark with the aim to encourage total solutions for combined Cleantech system offers. The project has achieved to establish a Cleantech register of 600 Nordic Cleantech companies, a network of 86 member enterprises, produced several publications and brochures for direct technology promotion and a website for direct access to company profiles and contact data. The project partners have attended 14 relevant international Cleantech trade fairs and conferences and facilitated business-to-business contacts added by capacity building offers through two company workshops. The future challenge for the project partners and Nordic Cleantech will be to coordinate the numerous efforts within the Nordic countries in order to reach concerted action and binding of member companies for reliable services, an improved visibility and knowledge exchange. With Cleantech's growing market influence and public awareness, the need to develop total solutions is increasing likewise. Marketing efforts should be encouraged cross-sectional and cross-border among the various levels of involved actors from both the public and the private sector. (au)

  17. NETS - Danish participation. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Alsen, S [Grontmij - Carl Bro, Glostrup (Denmark); Theel, C [Baltic Sea Solutions, Holeby (Denmark)

    2008-12-15

    Within the NICe-funded project 'Nordic Environmental Technology Solutions (NETS)' a new type of networking at the Nordic level was organized in order to jointly exploit the rapidly growing market potential in the environmental technology sector. The project aimed at increased and professionalized commercialization of Nordic Cleantech in energy and water business segments through 1) closer cooperation and joint marketing activities, 2) a website, 3) cleantech product information via brochures and publications 4) and participating in relevant trade fairs and other industry events. Facilitating business-to-business activities was another core task for the NETS project partners from Norway, Sweden, Finland and Denmark with the aim to encourage total solutions for combined Cleantech system offers. The project has achieved to establish a Cleantech register of 600 Nordic Cleantech companies, a network of 86 member enterprises, produced several publications and brochures for direct technology promotion and a website for direct access to company profiles and contact data. The project partners have attended 14 relevant international Cleantech trade fairs and conferences and facilitated business-to-business contacts added by capacity building offers through two company workshops. The future challenge for the project partners and Nordic Cleantech will be to coordinate the numerous efforts within the Nordic countries in order to reach concerted action and binding of member companies for reliable services, an improved visibility and knowledge exchange. With Cleantech's growing market influence and public awareness, the need to develop total solutions is increasing likewise. Marketing efforts should be encouraged cross-sectional and cross-border among the various levels of involved actors from both the public and the private sector. (au)

  18. Higher-moment measurements of net-kaon, net-charge and net-proton multiplicity distributions at STAR

    International Nuclear Information System (INIS)

    Sarkar, Amal

    2014-01-01

    In this paper, we report the measurements of the various moments, such as mean, standard deviation (σ), skewness (S) and kurtosis (κ) of the net-kaon, net-charge and net-proton multiplicity distributions at mid-rapidity in Au + Au collisions from √(s NN )=7.7 to 200 GeV with the STAR experiment at RHIC. This work has been done with the aim to locate the critical point on the QCD phase diagram. These moments and their products are related to the thermodynamic susceptibilities of conserved quantities such as net baryon number, net charge, and net strangeness as well as to the correlation length of the system which diverges in an ideal infinite thermodynamic system at the critical point. For a finite system, existing for a finite time, a non-monotonic behavior of these variables would indicate the presence of the critical point. Furthermore, we also present the moment products Sσ, κσ 2 of net-kaon, net-charge and net-proton multiplicity distributions as a function of collision centrality and energy. The energy and the centrality dependence of higher moments and their products have been compared with different models

  19. Radiation balance of an alfalfa crop in Saudi Arabia

    International Nuclear Information System (INIS)

    Al-Yemeni, M.N.; Grace, J.

    1995-01-01

    Short-wave reflectivity or albedo is an important component of net radiation which represents the major determinant of radiation balance of crop surface. This study was conducted on an irrigated alfalfa crop field at Al-Kharj agricultural area in Saudi Arabia, grown according to normal agricultural practices. Data on radiation balance and crop cover were collected over a number of days from March to October 1986, crop albedo varying from 0–4 in early morning to 0–20 at noon, the overall mean value of the crop albedo being estimated at 0–26. The relation between the individual components of radiation balance was studied, and a significant correlation between incident radiation and net radiation was found. Possible causes responsible for changes in crop albedo were discussed. (author)

  20. Improving methyl ketone production in Escherichia coli by heterologous expression of NADH-dependent FabG

    DEFF Research Database (Denmark)

    Goh, Ee Been; Chen, Yan; Petzold, Christopher J.

    2018-01-01

    balance, as fatty acid-derived pathways face the systematic metabolic challenge of net NADPH consumption (in large part, resulting from the key fatty acid biosynthetic enzyme FabG [β-ketoacyl-ACP reductase]) and net NADH production. In this study, we attempted to mitigate cofactor imbalance...... by heterologously expressing NADH-dependent, rather than NADPH-dependent, versions of FabG identified in previous studies. Of the four NADH-dependent versions of FabG tested in our previously best-reported methyl ketone-producing strain (EGS1895), the version from Acholeplasma laidlawii (Al_FabG) showed...... for the base strain (EGS1895) under fermentation conditions optimized in this study. Shotgun proteomic data for strains EGS2920 and EGS1895 during fed-batch fermentation were consistent with the goal of alleviating NADPH limitation through expression of Al_FabG. For example, relative to strain EGS1895, strain...

  1. Perineuronal Net Protein Neurocan Inhibits NCAM/EphA3 Repellent Signaling in GABAergic Interneurons.

    Science.gov (United States)

    Sullivan, Chelsea S; Gotthard, Ingo; Wyatt, Elliott V; Bongu, Srihita; Mohan, Vishwa; Weinberg, Richard J; Maness, Patricia F

    2018-04-18

    Perineuronal nets (PNNs) are implicated in closure of critical periods of synaptic plasticity in the brain, but the molecular mechanisms by which PNNs regulate synapse development are obscure. A receptor complex of NCAM and EphA3 mediates postnatal remodeling of inhibitory perisomatic synapses of GABAergic interneurons onto pyramidal cells in the mouse frontal cortex necessary for excitatory/inhibitory balance. Here it is shown that enzymatic removal of PNN glycosaminoglycan chains decreased the density of GABAergic perisomatic synapses in mouse organotypic cortical slice cultures. Neurocan, a key component of PNNs, was expressed in postnatal frontal cortex in apposition to perisomatic synapses of parvalbumin-positive interneurons. Polysialylated NCAM (PSA-NCAM), which is required for ephrin-dependent synapse remodeling, bound less efficiently to neurocan than mature, non-PSA-NCAM. Neurocan bound the non-polysialylated form of NCAM at the EphA3 binding site within the immunoglobulin-2 domain. Neurocan inhibited NCAM/EphA3 association, membrane clustering of NCAM/EphA3 in cortical interneuron axons, EphA3 kinase activation, and ephrin-A5-induced growth cone collapse. These studies delineate a novel mechanism wherein neurocan inhibits NCAM/EphA3 signaling and axonal repulsion, which may terminate postnatal remodeling of interneuron axons to stabilize perisomatic synapses in vivo.

  2. Balanced microwave filters

    CERN Document Server

    Hong, Jiasheng; Medina, Francisco; Martiacuten, Ferran

    2018-01-01

    This book presents and discusses strategies for the design and implementation of common-mode suppressed balanced microwave filters, including, narrowband, wideband, and ultra-wideband filters This book examines differential-mode, or balanced, microwave filters by discussing several implementations of practical realizations of these passive components. Topics covered include selective mode suppression, designs based on distributed and semi-lumped approaches, multilayer technologies, defect ground structures, coupled resonators, metamaterials, interference techniques, and substrate integrated waveguides, among others. Divided into five parts, Balanced Microwave Filters begins with an introduction that presents the fundamentals of balanced lines, circuits, and networks. Part 2 covers balanced transmission lines with common-mode noise suppression, including several types of common-mode filters and the application of such filters to enhance common-mode suppression in balanced bandpass filters. Next, Part 3 exa...

  3. Balancing Trust and Control

    DEFF Research Database (Denmark)

    Jagd, Søren

    2010-01-01

    of balancing trust and control becomes an issue that deserve ongoing attention. This paper adds to the discussion on the relation between trust and control by showing that the process perspective reframes the problem of balancing trust and control. More generally, by demonstrating the importance of the process......The purpose of this paper is to show that conceptualizing trust and control as interactively related processes, as opposed to more static conceptualizations of the two concepts and the relations between them, adds importantly towards understanding the challenges involved in balancing of trust...... on trust and control made the problem of finding a balance between trust and control a once and for all decision the process perspective introduced here implies that balancing trust and control is an ongoing process of balancing and rebalancing. The implication for management is that the problem...

  4. Balance and flexibility.

    Science.gov (United States)

    2003-12-01

    The 'work-life balance' and flexible working are currently key buzz terms in the NHS. Those looking for more information on these topics should visit Flexibility at www.flexibility.co.uk for a host of resources designed to support new ways of working, including information on flexible workers and flexible rostering, the legal balancing act for work-life balance and home working.

  5. Balance of power

    OpenAIRE

    Lucas, James Raymond

    2012-01-01

    This Paper argues that the efficiency distribution of players in a game determines how aggressively these players interact. We formalize the idea of balance of power: players fight very inefficient players but play softly versus equally (or more) efficient players. This theory of conduct predicts that entry by new firms leads to a less aggressive outcome if it creates a balance of power. A balance of power is created if more players get technologies that are close to the most efficient techno...

  6. Work-Life Balance

    OpenAIRE

    Kvasničková, Katarína

    2011-01-01

    The subject of this thesis is Work-Life Balance - the reconciliation of professional and personal lives. The primary objective of this work is to analyze employee satisfaction in achieving a balance between the professional and personal life and to develop recommendations for employer on that basis. The theoretical portion of this work defines the issues surrounding Work-Life Balance and tools that employees can use to harmonize the two with an analysis of applications in the Czech Republic a...

  7. Application and Theory of Petri Nets

    DEFF Research Database (Denmark)

    This volume contains the proceedings of the 13th International Conference onApplication and Theory of Petri Nets, held in Sheffield, England, in June 1992. The aim of the Petri net conferences is to create a forum for discussing progress in the application and theory of Petri nets. Typically....... Balbo and W. Reisig, 18 submitted papers, and seven project papers. The submitted papers and project presentations were selectedby the programme committee and a panel of referees from a large number of submissions....

  8. TwiddleNet: Smartphones as Personal Servers

    OpenAIRE

    Gurminder, Singh; Center for the Study of Mobile Devices and Communications

    2012-01-01

    TwiddleNet uses smartphones as personal servers to enable instant content capture and dissemination for firstresponders. It supports the information sharing needs of first responders in the early stages of an emergency response operation. In TwiddleNet, content, once captured, is automatically tagged and disseminated using one of the several networking channels available in smartphones. TwiddleNet pays special attention to minimizing the equipment, network set-up time, and content...

  9. 2004 energy balances and electricity profiles

    International Nuclear Information System (INIS)

    2007-02-01

    The Energy Balances and Electricity Profiles 2004 is the thirteenth issue in an internationally series of comparable energy data for selected developing countries. The data are arranged to show energy production, trade, conversion and consumption for each fuel used in the country. This publication is a source of overall consumption statistics of energy commodities in all sectors. Special electricity profiles for an additional group of countries are published to cover, exclusively, detailed information on production, trade and consumption of electricity, net installed capacity and thermal power plant input for selected developing countries

  10. Energy Balance Bowen Ratio (EBBR) Handbook

    Energy Technology Data Exchange (ETDEWEB)

    Cook, D. R. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2016-01-01

    The Energy Balance Bowen Ratio (EBBR) system produces 30-minute estimates of the vertical fluxes of sensible and latent heat at the local surface. Flux estimates are calculated from observations of net radiation, soil surface heat flux, and the vertical gradients of temperature and relative humidity (RH). Meteorological data collected by the EBBR are used to calculate bulk aerodynamic fluxes, which are used in the Bulk Aerodynamic Technique (BA) EBBR value-added product (VAP) to replace sunrise and sunset spikes in the flux data. A unique aspect of the system is the automatic exchange mechanism (AEM), which helps to reduce errors from instrument offset drift.

  11. Professional Visual Basic 2010 and .NET 4

    CERN Document Server

    Sheldon, Bill; Sharkey, Kent

    2010-01-01

    Intermediate and advanced coverage of Visual Basic 2010 and .NET 4 for professional developers. If you've already covered the basics and want to dive deep into VB and .NET topics that professional programmers use most, this is your book. You'll find a quick review of introductory topics-always helpful-before the author team of experts moves you quickly into such topics as data access with ADO.NET, Language Integrated Query (LINQ), security, ASP.NET web programming with Visual Basic, Windows workflow, threading, and more. You'll explore all the new features of Visual Basic 2010 as well as all t

  12. Pro Agile NET Development with Scrum

    CERN Document Server

    Blankenship, Jerrel; Millett, Scott

    2011-01-01

    Pro Agile .NET Development with SCRUM guides you through a real-world ASP.NET project and shows how agile methodology is put into practice. There is plenty of literature on the theory behind agile methodologies, but no book on the market takes the concepts of agile practices and applies these in a practical manner to an end-to-end ASP.NET project, especially the estimating, requirements and management aspects of a project. Pro Agile .NET Development with SCRUM takes you through the initial stages of a project - gathering requirements and setting up an environment - through to the development a

  13. Annual and Seasonal Mean Net Evaporation Rates of the Red Sea Water during Jan 1958 - Dec 2007

    OpenAIRE

    Nassir, Sahbaldeen Abdulaziz

    2012-01-01

    Data set including sea level, temperature, salinity, and current from Simple Ocean Data Assimilation (SODA) is used in this study to estimate the mean net annually and seasonally evaporation rates. Then wind data is used to examine its impact on the evaporation. This work calculated the seasonal and annual evaporation rates based on assumption of that there is no net mass transport (balanced). Hence, the difference in the transport supposed to be equal to the water that has eva...

  14. Experiments and simulation of a net closing mechanism for tether-net capture of space debris

    Science.gov (United States)

    Sharf, Inna; Thomsen, Benjamin; Botta, Eleonora M.; Misra, Arun K.

    2017-10-01

    This research addresses the design and testing of a debris containment system for use in a tether-net approach to space debris removal. The tether-net active debris removal involves the ejection of a net from a spacecraft by applying impulses to masses on the net, subsequent expansion of the net, the envelopment and capture of the debris target, and the de-orbiting of the debris via a tether to the chaser spacecraft. To ensure a debris removal mission's success, it is important that the debris be successfully captured and then, secured within the net. To this end, we present a concept for a net closing mechanism, which we believe will permit consistently successful debris capture via a simple and unobtrusive design. This net closing system functions by extending the main tether connecting the chaser spacecraft and the net vertex to the perimeter and around the perimeter of the net, allowing the tether to actuate closure of the net in a manner similar to a cinch cord. A particular embodiment of the design in a laboratory test-bed is described: the test-bed itself is comprised of a scaled-down tether-net, a supporting frame and a mock-up debris. Experiments conducted with the facility demonstrate the practicality of the net closing system. A model of the net closure concept has been integrated into the previously developed dynamics simulator of the chaser/tether-net/debris system. Simulations under tether tensioning conditions demonstrate the effectiveness of the closure concept for debris containment, in the gravity-free environment of space, for a realistic debris target. The on-ground experimental test-bed is also used to showcase its utility for validating the dynamics simulation of the net deployment, and a full-scale automated setup would make possible a range of validation studies of other aspects of a tether-net debris capture mission.

  15. Balance equations for a relativistic plasma. Pt. 1

    International Nuclear Information System (INIS)

    Hebenstreit, H.

    1983-01-01

    Relativistic power moments of the four-momentum are decomposed according to a macroscopic four-velocity. The thus obtained quantities are identified as relativistic generalization of the nonrelativistic orthogonal moments, e.g. diffusion flow, heat flow, pressure, etc. From the relativistic Boltzmann equation we then derive balance equations for these quantities. Explicit expressions for the relativistic mass conservation, energy balance, pressure balance, heat flow balance are presented. The weak relativistic limit is discussed. The derivation of higher order balance equations is sketched. (orig.)

  16. Identifying Balance in a Balanced Scorecard System

    Science.gov (United States)

    Aravamudhan, Suhanya; Kamalanabhan, T. J.

    2007-01-01

    In recent years, strategic management concepts seem to be gaining greater attention from the academicians and the practitioner's alike. Balanced Scorecard (BSC) concept is one such management concepts that has spread in worldwide business and consulting communities. The BSC translates mission and vision statements into a comprehensive set of…

  17. Net carbon exchange across the Arctic tundra-boreal forest transition in Alaska 1981-2000

    Science.gov (United States)

    Thompson, Catharine Copass; McGuire, A.D.; Clein, Joy S.; Chapin, F. S.; Beringer, J.

    2006-01-01

    Shifts in the carbon balance of high-latitude ecosystems could result from differential responses of vegetation and soil processes to changing moisture and temperature regimes and to a lengthening of the growing season. Although shrub expansion and northward movement of treeline should increase carbon inputs, the effects of these vegetation changes on net carbon exchange have not been evaluated. We selected low shrub, tall shrub, and forest tundra sites near treeline in northwestern Alaska, representing the major structural transitions expected in response to warming. In these sites, we measured aboveground net primary production (ANPP) and vegetation and soil carbon and nitrogen pools, and used these data to parameterize the Terrestrial Ecosystem Model. We simulated the response of carbon balance components to air temperature and precipitation trends during 1981-2000. In areas experiencing warmer and dryer conditions, Net Primary Production (NPP) decreased and heterotrophic respiration (R H ) increased, leading to a decrease in Net Ecosystem Production (NEP). In warmer and wetter conditions NPP increased, but the response was exceeded by an increase in R H ; therefore, NEP also decreased. Lastly, in colder and wetter regions, the increase in NPP exceeded a small decline in R H , leading to an increase in NEP. The net effect for the region was a slight gain in ecosystem carbon storage over the 20 year period. This research highlights the potential importance of spatial variability in ecosystem responses to climate change in assessing the response of carbon storage in northern Alaska over the last two decades. ?? Springer 2005.

  18. Testing the performance of a Dynamic Global Ecosystem Model: Water balance, carbon balance, and vegetation structure

    Science.gov (United States)

    Kucharik, Christopher J.; Foley, Jonathan A.; Delire, Christine; Fisher, Veronica A.; Coe, Michael T.; Lenters, John D.; Young-Molling, Christine; Ramankutty, Navin; Norman, John M.; Gower, Stith T.

    2000-09-01

    While a new class of Dynamic Global Ecosystem Models (DGEMs) has emerged in the past few years as an important tool for describing global biogeochemical cycles and atmosphere-biosphere interactions, these models are still largely untested. Here we analyze the behavior of a new DGEM and compare the results to global-scale observations of water balance, carbon balance, and vegetation structure. In this study, we use version 2 of the Integrated Biosphere Simulator (IBIS), which includes several major improvements and additions to the prototype model developed by Foley et al. [1996]. IBIS is designed to be a comprehensive model of the terrestrial biosphere; the model represents a wide range of processes, including land surface physics, canopy physiology, plant phenology, vegetation dynamics and competition, and carbon and nutrient cycling. The model generates global simulations of the surface water balance (e.g., runoff), the terrestrial carbon balance (e.g., net primary production, net ecosystem exchange, soil carbon, aboveground and belowground litter, and soil CO2 fluxes), and vegetation structure (e.g., biomass, leaf area index, and vegetation composition). In order to test the performance of the model, we have assembled a wide range of continental and global-scale data, including measurements of river discharge, net primary production, vegetation structure, root biomass, soil carbon, litter carbon, and soil CO2 flux. Using these field data and model results for the contemporary biosphere (1965-1994), our evaluation shows that simulated patterns of runoff, NPP, biomass, leaf area index, soil carbon, and total soil CO2 flux agree reasonably well with measurements that have been compiled from numerous ecosystems. These results also compare favorably to other global model results.

  19. Price smarter on the Net.

    Science.gov (United States)

    Baker, W; Marn, M; Zawada, C

    2001-02-01

    Companies generally have set prices on the Internet in two ways. Many start-ups have offered untenably low prices in a rush to capture first-mover advantage. Many incumbents have simply charged the same prices on-line as they do off-line. Either way, companies are missing a big opportunity. The fundamental value of the Internet lies not in lowering prices or making them consistent but in optimizing them. After all, if it's easy for customers to compare prices on the Internet, it's also easy for companies to track customers' behavior and adjust prices accordingly. The Net lets companies optimize prices in three ways. First, it lets them set and announce prices with greater precision. Different prices can be tested easily, and customers' responses can be collected instantly. Companies can set the most profitable prices, and they can tap into previously hidden customer demand. Second, because it's so easy to change prices on the Internet, companies can adjust prices in response to even small fluctuations in market conditions, customer demand, or competitors' behavior. Third, companies can use the clickstream data and purchase histories that it collects through the Internet to segment customers quickly. Then it can offer segment-specific prices or promotions immediately. By taking full advantage of the unique possibilities afforded by the Internet to set prices with precision, adapt to changing circumstances quickly, and segment customers accurately, companies can get their pricing right. It's one of the ultimate drivers of e-business success.

  20. Daily variation in net primary production and net calcification in coral reef communities exposed to elevated pCO2

    Directory of Open Access Journals (Sweden)

    S. Comeau

    2017-07-01

    Full Text Available The threat represented by ocean acidification (OA for coral reefs has received considerable attention because of the sensitivity of calcifiers to changing seawater carbonate chemistry. However, most studies have focused on the organismic response of calcification to OA, and only a few have addressed community-level effects, or investigated parameters other than calcification, such as photosynthesis. Light (photosynthetically active radiation, PAR is a driver of biological processes on coral reefs, and the possibility that these processes might be perturbed by OA has important implications for community function. Here we investigate how CO2 enrichment affects the relationships between PAR and community net O2 production (Pnet, and between PAR and community net calcification (Gnet, using experiments on three coral communities constructed to match (i the back reef of Mo'orea, French Polynesia, (ii the fore reef of Mo'orea, and (iii the back reef of O'ahu, Hawaii. The results were used to test the hypothesis that OA affects the relationship between Pnet and Gnet. For the three communities tested, pCO2 did not affect the Pnet–PAR relationship, but it affected the intercept of the hyperbolic tangent curve fitting the Gnet–PAR relationship for both reef communities in Mo'orea (but not in O'ahu. For the three communities, the slopes of the linear relationships between Pnet and Gnet were not affected by OA, although the intercepts were depressed by the inhibitory effect of high pCO2 on Gnet. Our result indicates that OA can modify the balance between net calcification and net photosynthesis of reef communities by depressing community calcification, but without affecting community photosynthesis.

  1. HANPP Collection: Human Appropriation of Net Primary Productivity as a Percentage of Net Primary Productivity

    Data.gov (United States)

    National Aeronautics and Space Administration — The Human Appropriation of Net Primary Productivity (HANPP) as a Percentage of Net Primary Product (NPP) portion of the HANPP Collection represents a map identifying...

  2. Balance og stofskifte

    DEFF Research Database (Denmark)

    2011-01-01

    Udstilling på Medicinsk Museion. Baseret på bevilling fra Assens Fond. Se mere på http://www.museion.ku.dk/whats-on/exhibitions/balance-and-metabolism/......Udstilling på Medicinsk Museion. Baseret på bevilling fra Assens Fond. Se mere på http://www.museion.ku.dk/whats-on/exhibitions/balance-and-metabolism/...

  3. Conclusion: The balanced company

    DEFF Research Database (Denmark)

    Scheuer, John Damm; Jensen, Inger

    2013-01-01

    This concluding chapter brings together the various research findings of the book "The balanced company - organizing for the 21st Century" and develops a general overview of their implications for our understanding of the balancing processes unfolding in companies and organizations....

  4. A Smartphone Inertial Balance

    Science.gov (United States)

    Barrera-Garrido, Azael

    2017-01-01

    In order to measure the mass of an object in the absence of gravity, one useful tool for many decades has been the inertial balance. One of the simplest forms of inertial balance is made by two mass holders or pans joined together with two stiff metal plates, which act as springs.

  5. Mobility Balance Sheet 2009

    International Nuclear Information System (INIS)

    Jorritsma, P.; Derriks, H.; Francke, J.; Gordijn, H.; Groot, W.; Harms, L.; Van der Loop, H.; Peer, S.; Savelberg, F.; Wouters, P.

    2009-06-01

    The Mobility Balance Sheet provides an overview of the state of the art of mobility in the Netherlands. In addition to describing the development of mobility this report also provides explanations for the growth of passenger and freight transport. Moreover, the Mobility Balance Sheet also focuses on a topical theme: the effects of economic crises on mobility. [nl

  6. Balance Disorders (For Parents)

    Science.gov (United States)

    ... This nerve sends signals to the brain that control hearing (auditory function) and help with balance (vestibular function). But the ears aren't the ... symptoms aren't necessarily a sign of a balance problem — or any other ... stumble and fall sometimes, especially toddlers just learning to walk and ...

  7. Trust-distrust Balance

    DEFF Research Database (Denmark)

    Jukka, Minna; Blomqvist, Kirsimarja; Li, Peter Ping

    2017-01-01

    notion of "guanxi" as personal ties. In contrast, the Finnish managers' view of trustworthiness was more associated with depersonalized organizational attributes. They emphasized the dimension of integrity, especially promise-keeping. In addition, tentative signs of trust ambivalence, as a balance...... opposites constitute a duality to be managed from the perspective of yin-yang balancing....

  8. Lust-Balance

    NARCIS (Netherlands)

    Wouters, Cas

    2007-01-01

    The concept of the lust-balance refers to the social organization and accompanying social codes (ideals and practices) regarding the relationship between the longing for sexual gratification and the longing for enduring relational intimacy. It thus draws attention to the balance between emotive

  9. Balancing for nonlinear systems

    NARCIS (Netherlands)

    Scherpen, J.M.A.

    1993-01-01

    We present a method of balancing for nonlinear systems which is an extension of balancing for linear systems in the sense that it is based on the input and output energy of a system. It is a local result, but gives 'broader' results than we obtain by just linearizing the system. Furthermore, the

  10. Chemical Equation Balancing.

    Science.gov (United States)

    Blakley, G. R.

    1982-01-01

    Reviews mathematical techniques for solving systems of homogeneous linear equations and demonstrates that the algebraic method of balancing chemical equations is a matter of solving a system of homogeneous linear equations. FORTRAN programs using this matrix method to chemical equation balancing are available from the author. (JN)

  11. Net energy yield from production of conventional oil

    International Nuclear Information System (INIS)

    Dale, Michael; Krumdieck, Susan; Bodger, Pat

    2011-01-01

    Historic profitability of bringing oil to market was profound, but most easy oil has been developed. Higher cost resources, such as tar sands and deep off-shore, are considered the best prospects for the future. Economic modelling is currently used to explore future price scenarios commensurate with delivering fuel to market. Energy policy requires modelling scenarios capturing the complexity of resource and extraction aspects as well as the economic profitability of different resources. Energy-return-on-investment (EROI) expresses the profitability of bringing energy products to the market. Net energy yield (NEY) is related to the EROI. NEY is the amount of energy less expenditures necessary to deliver a fuel to the market. This paper proposes a pattern for EROI of oil production, based on historic oil development trends. Methodology and data for EROI is not agreed upon. The proposed EROI function is explored in relation to the available data and used to attenuate the International Energy Agency (IEA) world oil production scenarios to understand the implications of future declining EROI on net energy yield. The results suggest that strategies for management and mitigation of deleterious effects of a peak in oil production are more urgent than might be suggested by analyses focussing only on gross production. - Highlights: → Brief introduction to methodological issues concerning net energy analysis. → Description of EROI function over the whole production cycle of an energy resource. → Calibration of this function to EROI data from historic oil production. → Application to determine the net energy yield from current global oil production. → Calculation of net energy yield from IEA projections of future oil production.

  12. Face recognition: Eigenface, elastic matching, and neural nets

    International Nuclear Information System (INIS)

    Zhang, J.; Lades, M.

    1997-01-01

    This paper is a comparative study of three recently proposed algorithms for face recognition: eigenface, autoassociation and classification neural nets, and elastic matching. After these algorithms were analyzed under a common statistical decision framework, they were evaluated experimentally on four individual data bases, each with a moderate subject size, and a combined data base with more than a hundred different subjects. Analysis and experimental results indicate that the eigenface algorithm, which is essentially a minimum distance classifier, works well when lighting variation is small. Its performance deteriorates significantly as lighting variation increases. The elastic matching algorithm, on the other hand, is insensitive to lighting, face position, and expression variations and therefore is more versatile. The performance of the autoassociation and classification nets is upper bounded by that of the eigenface but is more difficult to implement in practice

  13. Energy balance and stability

    International Nuclear Information System (INIS)

    Hammer, R.

    1982-01-01

    The energy balance of the outer atmospheres of solarlike stars is discussed. The energy balance of open coronal regions is considered, discussing the construction and characteristics of models of such regions in some detail. In particular, the temperature as a function of height is considered, as are the damping length dependence of the global energy balance in the region between the base of the transition region and the critical point, and the effects of changing the amount of coronal heating, the stellar mass, and the stellar radius. Models of coronal loops are more briefly discussed. The chromosphere is then included in the discussion of the energy balance, and the connection between global energy balance and global thermal stability is addressed. The observed positive correlations between the chromospheric and coronal energy losses and the pressure of the transition region is qualitatively explained

  14. Balancing Trust and Control

    DEFF Research Database (Denmark)

    Jagd, Søren

    This paper focuses on the leadership challenge of balancing trust and control. The relation between trust and control has for a long time been a puzzling issue for management researchers. In the paper I first show that there has been a dramatic change in the way the relation between trust...... and control has been conceptualized in trust research. While the relation between trust and control earlier was conceptualized as a more or less stable balance between trust and control, more recent research conceptualizes the relation between trust and control more as a dynamical process that involves...... an ongoing process of balancing the relation between trust and control. Second, taking the departure in the recent conceptualization of the balance between trust and control as an interactive process I discuss the challenges for management in handling this more subtle balancing of trust and control...

  15. How the Army Meter Data Management System (MDMS) Can Help on the Path to Net Zero

    Science.gov (United States)

    2011-05-10

    NY) • Meets DoD cyber-security requirements – Received Authority to Operate from Army NETCOM effective 23 April 2010 – Received Certificate of...How MDMS supports Net Zero Goals (cont) 4. Measure Production/Consumption balance a. Only way to demonstrate position on glide path to Net Zero 5...2010001D To 8 Aug 2010 00 00 En•l’iY f*ttk COnWtnptlon J96S9U81’ WII FillCilftl .. Totol , ......... ~ Metert - Met el\\ r;’l £1Htr1< 1....-J G.n

  16. Carbon balances during land conversion in early bioenergy systems

    Science.gov (United States)

    Zenone, T.; Chen, J.; Gelfand, I.; Robertson, G. P.; Hamilton, S. K.

    2012-12-01

    In this study, we established a field experiment and deployed seven eddy-covariance towers to quantify the roles of land use change and the subsequent carbon (C) balances of three different bioenergy systems (corn, switchgrass, and mixed prairie species) that were developed from two historical land use types: monocultural grasslands dominated by smooth brome (Bromus inermis Leyss) and lands in the Conservation Reserve Program (CRP). Three CRP fields and three cropland fields were converted to soybean in 2009 (conversion year) before establishing the cellulosic biofuel cropping systems in 2010 (establishment year). A CRP perennial grassland site was kept undisturbed as a reference. Conversion of CRP to soybean induced net C emissions during the conversion year (134 -262 g C m-2 yr-1), while in the same year the net C balance at the CRP grassland reference was -35 g C m-2 yr-1 (i.e., net C sequestration). The establishment of switchgrass and mixed prairie induced a cumulative C balance of -113 g C m-2 (switchgrass from CRP), 250 g C m-2 (switchgrass from cropland), 706 g C m-2 (mixed prairie from CRP), and 59 g C m-2 (mixed prairie from cropland) over the three-year study period. The cumulative three-year C balance of corn converted from CRP and from cropland was -151 g C m-2 and -183 g C m-2, respectively. Eddy flux measurements during cellulosic biofuel crop establishment reveal annual changes in C balance that cannot be detected using conventional mass balance approaches. When end-use of harvested biomass was considered, the C balances for all studied systems, except the reference site, exhibited large C emissions ranging from 150 to 990 g C m-2 over the three-year conversion phase.

  17. Economic effect of reducing nitrogen and phosphorus mass balance on Wisconsin and Québec dairy farms.

    Science.gov (United States)

    Pellerin, D; Charbonneau, E; Fadul-Pacheco, L; Soucy, O; Wattiaux, M A

    2017-10-01

    Our objective was to explore the trade-offs between economic performance (farm net income, FNI) and environmental outcomes (whole-farm P and N balances) of dairy farms in Wisconsin (WI; United States) and Québec (QC; Canada). An Excel-based linear program model (N-CyCLES; nutrient cycling: crops, livestock, environment, and soil) was developed to optimize feeding, cropping, and manure management as a single unit of management. In addition to FNI, P and N balances model outputs included (1) the mix of up to 9 home-grown and 17 purchased feeds for up to 5 animal groups, (2) the mix of up to 5 crop rotations in up to 5 land units and c) the mix of up to 7 fertilizers (solid and liquid manure and 5 commercial fertilizers) to allocate in each land unit. The model was parameterized with NRC nutritional guidelines and regional nutrient management planning rules. Simulations were conducted on a typical WI farm of 107 cows and 151 ha of cropland and, a Southern QC farm of 87 cows and 142 ha of cropland and all results were expressed per kg of fat- and protein-corrected milk (FPCM). In absence of constraints on P and N balances, maximum FNI was 0.12 and 0.11 $/kg of FPCM for WI and QC, respectively, with P and N balances of 1.05 and 14.29 g/kg of FPCM in WI but 0.60 and 15.70 g/kg of FPCM in QC. The achievable reduction (balance at maximum FNI minus balance when the simulation objective was to minimize P or N balance) was 0.31 and 0.54 g of P/kg of FPCM (29 and 89% reduction), but 2.37 and 3.31 g of N/kg of FPCM (17 and 24% reduction) in WI and QC, respectively. Among other factors, differences in animal unit per hectare and reliance on biological N fixation may have contributed to lower achievable reductions of whole-farm balances in WI compared with QC. Subsequent simulations to maximize FNI under increasing constraints on nutrient balances revealed that it was possible to reduce P balance, N balance, and both together by up to 33% without a substantial effect on FNI

  18. Reduction rules for reset/inhibitor nets

    NARCIS (Netherlands)

    Verbeek, H.M.W.; Wynn, M.T.; Aalst, van der W.M.P.; Hofstede, ter A.H.M.

    2010-01-01

    Reset/inhibitor nets are Petri nets extended with reset arcs and inhibitor arcs. These extensions can be used to model cancellation and blocking. A reset arc allows a transition to remove all tokens from a certain place when the transition fires. An inhibitor arc can stop a transition from being

  19. Verifying generalized soundness for workflow nets

    NARCIS (Netherlands)

    Hee, van K.M.; Oanea, O.I.; Sidorova, N.; Voorhoeve, M.; Virbitskaite, I.; Voronkov, A.

    2007-01-01

    We improve the decision procedure from [10] for the problem of generalized soundness of workflow nets. A workflow net is generalized sound iff every marking reachable from an initial marking with k tokens on the initial place terminates properly, i.e. it can reach a marking with k tokens on the

  20. A Brief Introduction to Coloured Petri Nets

    DEFF Research Database (Denmark)

    Jensen, Kurt

    1997-01-01

    Coloured Petri Nets (CP-nets or CPN) is a graphical oriented language for design, specification, simulation and verification of systems. It is in particular well- suited for systems in which communication, synchronisation and resource sharing are important. Typical examples of application areas a...

  1. Net analyte signal based statistical quality control

    NARCIS (Netherlands)

    Skibsted, E.T.S.; Boelens, H.F.M.; Westerhuis, J.A.; Smilde, A.K.; Broad, N.W.; Rees, D.R.; Witte, D.T.

    2005-01-01

    Net analyte signal statistical quality control (NAS-SQC) is a new methodology to perform multivariate product quality monitoring based on the net analyte signal approach. The main advantage of NAS-SQC is that the systematic variation in the product due to the analyte (or property) of interest is

  2. 47 CFR 69.302 - Net investment.

    Science.gov (United States)

    2010-10-01

    ...) Investment in Accounts 2002, 2003 and to the extent such inclusions are allowed by this Commission, Account... Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES (CONTINUED) ACCESS CHARGES Apportionment of Net Investment § 69.302 Net investment. (a) Investment in Accounts 2001, 1220 and Class B Rural...

  3. Asynchronous stream processing with S-Net

    NARCIS (Netherlands)

    Grelck, C.; Scholz, S.-B.; Shafarenko, A.

    2010-01-01

    We present the rationale and design of S-Net, a coordination language for asynchronous stream processing. The language achieves a near-complete separation between the application code, written in any conventional programming language, and the coordination/communication code written in S-Net. Our

  4. Dynamic response of the thermometric net radiometer

    Science.gov (United States)

    J. D. Wilson; W. J. Massman; G. E. Swaters

    2009-01-01

    We computed the dynamic response of an idealized thermometric net radiometer, when driven by an oscillating net longwave radiation intended roughly to simulate rapid fluctuations of the radiative environment such as might be expected during field use of such devices. The study was motivated by curiosity as to whether non-linearity of the surface boundary conditions...

  5. 78 FR 72451 - Net Investment Income Tax

    Science.gov (United States)

    2013-12-02

    ... Net Investment Income Tax AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Withdrawal of... computation of net investment income. The regulations affect individuals, estates, and trusts whose incomes meet certain income thresholds. DATES: The proposed rule published December 5, 2012 (77 FR 72612), is...

  6. 10 CFR 436.20 - Net savings.

    Science.gov (United States)

    2010-01-01

    ... ENERGY ENERGY CONSERVATION FEDERAL ENERGY MANAGEMENT AND PLANNING PROGRAMS Methodology and Procedures for Life Cycle Cost Analyses § 436.20 Net savings. For a retrofit project, net savings may be found by subtracting life cycle costs based on the proposed project from life cycle costs based on not having it. For a...

  7. Net Neutrality and Inflation of Traffic

    NARCIS (Netherlands)

    Peitz, M.; Schütt, F.

    2015-01-01

    Under strict net neutrality Internet service providers (ISPs) are required to carry data without any differentiation and at no cost to the content provider. We provide a simple framework with a monopoly ISP to evaluate different net neutrality rules. Content differs in its sensitivity to delay.

  8. The Net Neutrality Debate: The Basics

    Science.gov (United States)

    Greenfield, Rich

    2006-01-01

    Rich Greenfield examines the basics of today's net neutrality debate that is likely to be an ongoing issue for society. Greenfield states the problems inherent in the definition of "net neutrality" used by Common Cause: "Network neutrality is the principle that Internet users should be able to access any web content they choose and…

  9. Net neutrality and inflation of traffic

    NARCIS (Netherlands)

    Peitz, M.; Schütt, Florian

    Under strict net neutrality Internet service providers (ISPs) are required to carry data without any differentiation and at no cost to the content provider. We provide a simple framework with a monopoly ISP to evaluate the short-run effects of different net neutrality rules. Content differs in its

  10. 27 CFR 4.37 - Net contents.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Net contents. 4.37 Section 4.37 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY LIQUORS LABELING AND ADVERTISING OF WINE Labeling Requirements for Wine § 4.37 Net...

  11. Discrete, continuous, and hybrid petri nets

    CERN Document Server

    David, René

    2004-01-01

    Petri nets do not designate a single modeling formalism. In fact, newcomers to the field confess sometimes to be a little puzzled by the diversity of formalisms that are recognized under this "umbrella". Disregarding some extensions to the theoretical modeling capabilities, and looking at the level of abstraction of the formalisms, Condition/Event, Elementary, Place/Transition, Predicate/Transition, Colored, Object Oriented... net systems are frequently encountered in the literature. On the other side, provided with appropriate interpretative extensions, Controled Net Systems, Marking Diagrams (the Petri net generalization of State Diagrams), or the many-many variants in which time can be explicitly incorporated -Time(d), Deterministic, (Generalized) Stochastic, Fuzzy...- are defined. This represents another way to define practical formalisms that can be obtained by the "cro- product" of the two mentioned dimensions. Thus Petri nets constitute a modeling paradigm, understandable in a broad sense as "the total...

  12. Net charge fluctuations and local charge compensation

    International Nuclear Information System (INIS)

    Fu Jinghua

    2006-01-01

    We propose net charge fluctuation as a measure of local charge correlation length. It is demonstrated that, in terms of a schematic multiperipheral model, net charge fluctuation satisfies the same Quigg-Thomas relation as satisfied by charge transfer fluctuation. Net charge fluctuations measured in finite rapidity windows depend on both the local charge correlation length and the size of the observation window. When the observation window is larger than the local charge correlation length, the net charge fluctuation only depends on the local charge correlation length, while forward-backward charge fluctuations always have strong dependence on the observation window size. Net charge fluctuations and forward-backward charge fluctuations measured in the present heavy ion experiments show characteristic features similar to those from multiperipheral models. But the data cannot all be understood within this simple model

  13. Neural Net Safety Monitor Design

    Science.gov (United States)

    Larson, Richard R.

    2007-01-01

    The National Aeronautics and Space Administration (NASA) at the Dryden Flight Research Center (DFRC) has been conducting flight-test research using an F-15 aircraft (figure 1). This aircraft has been specially modified to interface a neural net (NN) controller as part of a single-string Airborne Research Test System (ARTS) computer with the existing quad-redundant flight control system (FCC) shown in figure 2. The NN commands are passed to FCC channels 2 and 4 and are cross channel data linked (CCDL) to the other computers as shown. Numerous types of fault-detection monitors exist in the FCC when the NN mode is engaged; these monitors would cause an automatic disengagement of the NN in the event of a triggering fault. Unfortunately, these monitors still may not prevent a possible NN hard-over command from coming through to the control laws. Therefore, an additional and unique safety monitor was designed for a single-string source that allows authority at maximum actuator rates but protects the pilot and structural loads against excessive g-limits in the case of a NN hard-over command input. This additional monitor resides in the FCCs and is executed before the control laws are computed. This presentation describes a floating limiter (FL) concept1 that was developed and successfully test-flown for this program (figure 3). The FL computes the rate of change of the NN commands that are input to the FCC from the ARTS. A window is created with upper and lower boundaries, which is constantly floating and trying to stay centered as the NN command rates are changing. The limiter works by only allowing the window to move at a much slower rate than those of the NN commands. Anywhere within the window, however, full rates are allowed. If a rate persists in one direction, it will eventually hit the boundary and be rate-limited to the floating limiter rate. When this happens, a persistent counter begins and after a limit is reached, a NN disengage command is generated. The

  14. Net energy from nuclear power

    International Nuclear Information System (INIS)

    Rotty, R.M.; Perry, A.M.; Reister, D.B.

    1975-11-01

    An analysis of net energy from nuclear power plants is dependent on a large number of variables and assumptions. The energy requirements as they relate to reactor type, concentration of uranium in the ore, enrichment tails assays, and possible recycle of uranium and plutonium were examined. Specifically, four reactor types were considered: pressurized water reactor, boiling water reactor, high temperature gas-cooled reactor, and heavy water reactor (CANDU). The energy requirements of systems employing both conventional (current) ores with uranium concentration of 0.176 percent and Chattanooga Shales with uranium concentration of 0.006 percent were determined. Data were given for no recycle, uranium recycle only, and uranium plus plutonium recycle. Starting with the energy requirements in the mining process and continuing through fuel reprocessing and waste storage, an evaluation of both electrical energy requirements and thermal energy requirements of each process was made. All of the energy, direct and indirect, required by the processing of uranium in order to produce electrical power was obtained by adding the quantities for the individual processes. The energy inputs required for the operation of a nuclear power system for an assumed life of approximately 30 years are tabulated for nine example cases. The input requirements were based on the production of 197,100,000 MWH(e), i.e., the operation of a 1000 MW(e) plant for 30 years with an average plant factor of 0.75. Both electrical requirements and thermal energy requirements are tabulated, and it should be emphasized that both quantities are needed. It was found that the electricity generated far exceeded the energy input requirements for all the cases considered

  15. Net energy benefits of carbon nanotube applications

    International Nuclear Information System (INIS)

    Zhai, Pei; Isaacs, Jacqueline A.; Eckelman, Matthew J.

    2016-01-01

    Highlights: • Life cycle net energy benefits are examined. • CNT-enabled and the conventional technologies are compared. • Flash memory with CNT switches show significant positive net energy benefit. • Lithium-ion batteries with MWCNT cathodes show positive net energy benefit. • Lithium-ion batteries with SWCNT anodes tend to exhibit negative net energy benefit. - Abstract: Implementation of carbon nanotubes (CNTs) in various applications can reduce material and energy requirements of products, resulting in energy savings. However, processes for the production of carbon nanotubes (CNTs) are energy-intensive and can require extensive purification. In this study, we investigate the net energy benefits of three CNT-enabled technologies: multi-walled CNT (MWCNT) reinforced cement used as highway construction material, single-walled CNT (SWCNT) flash memory switches used in cell phones and CNT anodes and cathodes used in lithium-ion batteries used in electric vehicles. We explore the avoided or additional energy requirement in the manufacturing and use phases and estimate the life cycle net energy benefits for each application. Additional scenario analysis and Monte Carlo simulation of parameter uncertainties resulted in probability distributions of net energy benefits, indicating that net energy benefits are dependent on the application with confidence intervals straddling the breakeven line in some cases. Analysis of simulation results reveals that SWCNT switch flash memory and MWCNT Li-ion battery cathodes have statistically significant positive net energy benefits (α = 0.05) and SWCNT Li-ion battery anodes tend to have negative net energy benefits, while positive results for MWCNT-reinforced cement were significant only under an efficient CNT production scenario and a lower confidence level (α = 0.1).

  16. Heat balance characteristics and water use efficiency of soybean community

    International Nuclear Information System (INIS)

    Lee, Y.S.; Im, J.N.

    1990-01-01

    A field experiment was conducted to study seasonal evapotranspiration above soybean canopy and its relationship with dry matter production by the Bowen ratio-energy balance method. The soybean ''Paldalkong'' was sown with the space of 40 * 10 cm at Suwon on May 27, 1988. The daily net radiation ranged from 59 to 76 percents of the total shortwave radiation under cloudless conditions, which was lower than cloud overcast condition with record 63 to 83 percents. The latent heat flux under overcast condition was sometimes larger than the sum of net radiation, implying transportation of energy by advection of ambient air

  17. PathNet: a tool for pathway analysis using topological information

    Directory of Open Access Journals (Sweden)

    Dutta Bhaskar

    2012-09-01

    Full Text Available Abstract Background Identification of canonical pathways through enrichment of differentially expressed genes in a given pathway is a widely used method for interpreting gene lists generated from high-throughput experimental studies. However, most algorithms treat pathways as sets of genes, disregarding any inter- and intra-pathway connectivity information, and do not provide insights beyond identifying lists of pathways. Results We developed an algorithm (PathNet that utilizes the connectivity information in canonical pathway descriptions to help identify study-relevant pathways and characterize non-obvious dependencies and connections among pathways using gene expression data. PathNet considers both the differential expression of genes and their pathway neighbors to strengthen the evidence that a pathway is implicated in the biological conditions characterizing the experiment. As an adjunct to this analysis, PathNet uses the connectivity of the differentially expressed genes among all pathways to score pathway contextual associations and statistically identify biological relations among pathways. In this study, we used PathNet to identify biologically relevant results in two Alzheimer’s disease microarray datasets, and compared its performance with existing methods. Importantly, PathNet identified de-regulation of the ubiquitin-mediated proteolysis pathway as an important component in Alzheimer’s disease progression, despite the absence of this pathway in the standard enrichment analyses. Conclusions PathNet is a novel method for identifying enrichment and association between canonical pathways in the context of gene expression data. It takes into account topological information present in pathways to reveal biological information. PathNet is available as an R workspace image from http://www.bhsai.org/downloads/pathnet/.

  18. Development of a Common Nordic Balance Settlement

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-02-15

    need for incentives to reduce imbalances. NordREG comprehends that there are advantages for vertically integrated companies if they can net their imbalances. These advantages might be reduced and competition enhanced if the balance settlement includes separate consumption imbalances and separate production imbalances per Elspot area. It is difficult and costly to harmonize the area of metering value processing requirements and data systems, but it is crucial that it is done in order to have a common Nordic retail market. Therefore it is important that a road map for the necessary harmonisation and standardisation of these differences is agreed in the first phase. The difference in load profile systems is a obstacle for a harmonised balance settlement regarding customers without hourly measurements. After these issues have been discussed and agreed, it is possible to decide a plan for the further work aiming at implementation of a common Nordic balance settlement, which will also include necessary changes in the legal and regulatory framework.

  19. Development of a Common Nordic Balance Settlement

    International Nuclear Information System (INIS)

    2006-02-01

    need for incentives to reduce imbalances. NordREG comprehends that there are advantages for vertically integrated companies if they can net their imbalances. These advantages might be reduced and competition enhanced if the balance settlement includes separate consumption imbalances and separate production imbalances per Elspot area. It is difficult and costly to harmonize the area of metering value processing requirements and data systems, but it is crucial that it is done in order to have a common Nordic retail market. Therefore it is important that a road map for the necessary harmonisation and standardisation of these differences is agreed in the first phase. The difference in load profile systems is a obstacle for a harmonised balance settlement regarding customers without hourly measurements. After these issues have been discussed and agreed, it is possible to decide a plan for the further work aiming at implementation of a common Nordic balance settlement, which will also include necessary changes in the legal and regulatory framework

  20. Load Balancing Scientific Applications

    Energy Technology Data Exchange (ETDEWEB)

    Pearce, Olga Tkachyshyn [Texas A & M Univ., College Station, TX (United States)

    2014-12-01

    The largest supercomputers have millions of independent processors, and concurrency levels are rapidly increasing. For ideal efficiency, developers of the simulations that run on these machines must ensure that computational work is evenly balanced among processors. Assigning work evenly is challenging because many large modern parallel codes simulate behavior of physical systems that evolve over time, and their workloads change over time. Furthermore, the cost of imbalanced load increases with scale because most large-scale scientific simulations today use a Single Program Multiple Data (SPMD) parallel programming model, and an increasing number of processors will wait for the slowest one at the synchronization points. To address load imbalance, many large-scale parallel applications use dynamic load balance algorithms to redistribute work evenly. The research objective of this dissertation is to develop methods to decide when and how to load balance the application, and to balance it effectively and affordably. We measure and evaluate the computational load of the application, and develop strategies to decide when and how to correct the imbalance. Depending on the simulation, a fast, local load balance algorithm may be suitable, or a more sophisticated and expensive algorithm may be required. We developed a model for comparison of load balance algorithms for a specific state of the simulation that enables the selection of a balancing algorithm that will minimize overall runtime.

  1. Pro visual C++/CLI and the net 35 platform

    CERN Document Server

    Fraser, Stephen

    2008-01-01

    Pro Visual C++/CLI and the .NET 3.5 Platform is about writing .NET applications using C++/CLI. While readers are learning the ins and outs of .NET application development, they will also be learning the syntax of C++, both old and new to .NET. Readers will also gain a good understanding of the .NET architecture. This is truly a .NET book applying C++ as its development language not another C++ syntax book that happens to cover .NET.

  2. Regular Expression Pocket Reference

    CERN Document Server

    Stubblebine, Tony

    2007-01-01

    This handy little book offers programmers a complete overview of the syntax and semantics of regular expressions that are at the heart of every text-processing application. Ideal as a quick reference, Regular Expression Pocket Reference covers the regular expression APIs for Perl 5.8, Ruby (including some upcoming 1.9 features), Java, PHP, .NET and C#, Python, vi, JavaScript, and the PCRE regular expression libraries. This concise and easy-to-use reference puts a very powerful tool for manipulating text and data right at your fingertips. Composed of a mixture of symbols and text, regular exp

  3. Regular expressions cookbook

    CERN Document Server

    Goyvaerts, Jan

    2009-01-01

    This cookbook provides more than 100 recipes to help you crunch data and manipulate text with regular expressions. Every programmer can find uses for regular expressions, but their power doesn't come worry-free. Even seasoned users often suffer from poor performance, false positives, false negatives, or perplexing bugs. Regular Expressions Cookbook offers step-by-step instructions for some of the most common tasks involving this tool, with recipes for C#, Java, JavaScript, Perl, PHP, Python, Ruby, and VB.NET. With this book, you will: Understand the basics of regular expressions through a

  4. Calibration of an experimental six component wind tunnel block balance using optical fibre sensors

    CSIR Research Space (South Africa)

    de Ponte, JD

    2016-05-01

    Full Text Available In order to meet the increasingly stringent requirements for wind tunnel balances, as expressed by the wind tunnel testing community, balance design philosophy needs to be further expanded to include alternative sensor, material, design...

  5. Design and development of an experimental six component wind tunnel block balance using optical fibre sensors.

    CSIR Research Space (South Africa)

    De Ponte, JD

    2014-05-01

    Full Text Available In order to meet the increasingly stringent requirements for wind tunnel balances, as expressed by the wind tunnel testing community, balance design philosophy needs to be further expanded to include alternative sensor, material, design...

  6. The influence of health policy and market factors on the hospital safety net.

    Science.gov (United States)

    Bazzoli, Gloria J; Lindrooth, Richard C; Kang, Ray; Hasnain-Wynia, Romana

    2006-08-01

    To examine how the financial pressures resulting from the Balanced Budget Act (BBA) of 1997 interacted with private sector pressures to affect indigent care provision. American Hospital Association Annual Survey, Area Resource File, InterStudy Health Maintenance Organization files, Current Population Survey, and Bureau of Primary Health Care data. We distinguished core and voluntary safety net hospitals in our analysis. Core safety net hospitals provide a large share of uncompensated care in their markets and have large indigent care patient mix. Voluntary safety net hospitals provide substantial indigent care but less so than core hospitals. We examined the effect of financial pressure in the initial year of the 1997 BBA on uncompensated care for three hospital groups. Data for 1996-2000 were analyzed using approaches that control for hospital and market heterogeneity. All urban U.S. general acute care hospitals with complete data for at least 2 years between 1996 and 2000, which totaled 1,693 institutions. Core safety net hospitals reduced their uncompensated care in response to Medicaid financial pressure. Voluntary safety net hospitals also responded in this way but only when faced with the combined forces of Medicaid and private sector payment pressures. Nonsafety net hospitals did not exhibit similar responses. Our results are consistent with theories of hospital behavior when institutions face reductions in payment. They raise concern given continuing state budget crises plus the focus of recent federal deficit reduction legislation intended to cut Medicaid expenditures.

  7. Errors in potassium balance

    International Nuclear Information System (INIS)

    Forbes, G.B.; Lantigua, R.; Amatruda, J.M.; Lockwood, D.H.

    1981-01-01

    Six overweight adult subjects given a low calorie diet containing adequate amounts of nitrogen but subnormal amounts of potassium (K) were observed on the Clinical Research Center for periods of 29 to 40 days. Metabolic balance of potassium was measured together with frequent assays of total body K by 40 K counting. Metabolic K balance underestimated body K losses by 11 to 87% (average 43%): the intersubject variability is such as to preclude the use of a single correction value for unmeasured losses in K balance studies

  8. Energy balance measurement

    DEFF Research Database (Denmark)

    Dhurandhar, N V; Schoeller, D; Brown, A W

    2015-01-01

    Energy intake (EI) and physical activity energy expenditure (PAEE) are key modifiable determinants of energy balance, traditionally assessed by self-report despite its repeated demonstration of considerable inaccuracies. We argue here that it is time to move from the common view that self......-reports of EI and PAEE are imperfect, but nevertheless deserving of use, to a view commensurate with the evidence that self-reports of EI and PAEE are so poor that they are wholly unacceptable for scientific research on EI and PAEE. While new strategies for objectively determining energy balance...... of energy balance....

  9. Altered MENIN expression disrupts the MAFA differentiation pathway in insulinoma.

    Science.gov (United States)

    Hamze, Z; Vercherat, C; Bernigaud-Lacheretz, A; Bazzi, W; Bonnavion, R; Lu, J; Calender, A; Pouponnot, C; Bertolino, P; Roche, C; Stein, R; Scoazec, J Y; Zhang, C X; Cordier-Bussat, M

    2013-12-01

    The protein MENIN is the product of the multiple endocrine neoplasia type I (MEN1) gene. Altered MENIN expression is one of the few events that are clearly associated with foregut neuroendocrine tumours (NETs), classical oncogenes or tumour suppressors being not involved. One of the current challenges is to understand how alteration of MENIN expression contributes to the development of these tumours. We hypothesised that MENIN might regulate factors maintaining endocrine-differentiated functions. We chose the insulinoma model, a paradigmatic example of well-differentiated pancreatic NETs, to study whether MENIN interferes with the expression of v-MAF musculoaponeurotic fibrosarcoma oncogene homologue A (MAFA), a master glucose-dependent transcription factor in differentiated β-cells. Immunohistochemical analysis of a series of human insulinomas revealed a correlated decrease in both MENIN and MAFA. Decreased MAFA expression resulting from targeted Men1 ablation was also consistently observed in mouse insulinomas. In vitro analyses using insulinoma cell lines showed that MENIN regulated MAFA protein and mRNA levels, and bound to Mafa promoter sequences. MENIN knockdown concomitantly decreased mRNA expression of both Mafa and β-cell differentiation markers (Ins1/2, Gck, Slc2a2 and Pdx1) and, in parallel, increased the proliferation rate of tumours as measured by bromodeoxyuridine incorporation. Interestingly, MAFA knockdown alone also increased proliferation rate but did not affect the expression of candidate proliferation genes regulated by MENIN. Finally, MENIN variants with missense mutations detected in patients with MEN1 lost the WT MENIN properties to regulate MAFA. Together, our findings unveil a previously unsuspected MENIN/MAFA connection regarding control of the β-cell differentiation/proliferation balance, which could contribute to tumorigenesis.

  10. Impact of bioenergy on regionalized nitrogen balances

    Science.gov (United States)

    Häußermann, Uwe; Klement, Laura; Bach, Martin

    2017-04-01

    Results of regionalized and overall net-N-balances are used to fulfil different reporting obligations, as well as input data for nitrate leaching modelling (Bach et al. 2014). For Germany, these regionalized net-N-balances are calculated for 402 administrative units on the NUTS-III-level (Landkreise and kreisfreie Städte in Germany), 16 administrative units on the NUTS-I-level (Bundesländer in Germany) and the whole country for every year from 1995 to 2015. The so far existing net-N-balancing method includes nitrogen inputs and outputs of crop production and animal husbandry, however, not the utilization of crops and farmyard manure for energy production (Bach et al. 2014). Due to the introduction of guaranteed feed in tariffs for electricity production from biomass by the German renewable energy law in 2000 and the introduction of more favourable conditions for electricity production from biogas in 2004 (EEG 2000, EEG 2004) in the frame of the German policy of energy transition towards renewable energies („Energiewende"), the electric capacity of biogas plants had a steep increase in the years afterwards, the installed electric capacity increased from 149 MW in 2004 to 5080 MW in 2015 (BMWi and AGEE Stat 2016). The cropping area for the production of energy cops for biogas production increased as well from 0.4 Mio ha in 2007 to 1.393 Mio ha in 2015 (Statista 2017). We introduced a method to calculate the nitrogen input via energy crops, farmyard manure and organic waste, output via biogas digestates and gaseous nitrogen losses via NH3, N2O, NOx and N2 during the anaerobic digestion, digestate storage and spreading on the field, the emission factors for these nitrogen species are obtained from the report on methods and data for the agricultural part of the German national greenhouse gas inventory and informative inventory report (Haenel et al. 2016). To obtain highly resolved information on the distribution and capacity of biogas plants on NUTS-III-level, we

  11. Application of deconvolution interferometry with both Hi-net and KiK-net data

    Science.gov (United States)

    Nakata, N.

    2013-12-01

    Application of deconvolution interferometry to wavefields observed by KiK-net, a strong-motion recording network in Japan, is useful for estimating wave velocities and S-wave splitting in the near surface. Using this technique, for example, Nakata and Snieder (2011, 2012) found changed in velocities caused by Tohoku-Oki earthquake in Japan. At the location of the borehole accelerometer of each KiK-net station, a velocity sensor is also installed as a part of a high-sensitivity seismograph network (Hi-net). I present a technique that uses both Hi-net and KiK-net records for computing deconvolution interferometry. The deconvolved waveform obtained from the combination of Hi-net and KiK-net data is similar to the waveform computed from KiK-net data only, which indicates that one can use Hi-net wavefields for deconvolution interferometry. Because Hi-net records have a high signal-to-noise ratio (S/N) and high dynamic resolution, the S/N and the quality of amplitude and phase of deconvolved waveforms can be improved with Hi-net data. These advantages are especially important for short-time moving-window seismic interferometry and deconvolution interferometry using later coda waves.

  12. KONVERGENSI DALAM PROGRAM NET CITIZEN JOURNALISM

    Directory of Open Access Journals (Sweden)

    Rhafidilla Vebrynda

    2017-06-01

    Full Text Available Di dalam artikel ini, peneliti ingin melihat perkembangan teknologi di Indonesia sebagai sebuah peluang untuk menjalankan sebuah program berita berbasis video kiriman masyarakat. Perkembangan teknologi tersebut adalah teknologi penyiaran, teknologi sosial media dan teknologi dalam proses produksi sebuah video. Di Indonesia, jumlah televisi semakin banyak. Setiap stasiun televisi harus bersaing untuk dapat bertahan hidup. Net TV merupakan sebuah stasiun televisi baru di Indonesia yang harus memiliki berbagai program unggulan baru agar dapat bersaing dengan televisi lainnya yang sudah ada. Net TV menggunakan berbagai platform media untuk menjalankan program Net Citizen Journalism (Net CJ. Penggunaan berbagai platform media dikenal dengan istilah multiplatform dan secara teoritis dikenal dengan istilah konvergensi. Konvergensi yaitu saat meleburnya domain-domain dalam berbagai media komunikasi. Artikel ini menggunakan metode studi kasus untuk melihat bagaimana konvergensi terjadi dalam proses pengelolaan program Net CJ. Teknik pengumpulan data adalah dengan wawancara mendalam, observasi dan studi dokumen. Wawancara mendalam dilakukan dari tiga sudut pandang yaitu dari pengelola program, pengguna/audience dan pengamat media. Penelitian ini menemukan bahwa dengan menggunakan berbagai platform media yang fungsinya berbeda, memiliki satu tujuan yang sama yaitu untuk menjalankan program Net CJ. Adapun berbagai platform dalam proses produksi program yaitu tayangan TV konvensional, streaming TV, website, aplikasi Net CJ, facebook, twitter, instagram dan path. Konvergensi media dijalankan dalam dua proses, yaitu proses produksi dan proses promosi program berita.

  13. Net Neutrality: Media Discourses and Public Perception

    Directory of Open Access Journals (Sweden)

    Christine Quail

    2010-01-01

    Full Text Available This paper analyzes media and public discourses surrounding net neutrality, with particular attention to public utility philosophy, from a critical perspective. The article suggests that further public education about net neutrality would be beneficial. The first portion of this paper provides a survey of the existing literature surrounding net neutrality, highlighting the contentious debate between market-based and public interest perspectives. In order to contextualize the debate, an overview of public utility philosophy is provided, shedding light on how the Internet can be conceptualized as a public good. Following this discussion, an analysis of mainstream media is presented, exploring how the media represents the issue of net neutrality and whether or not the Internet is discussed through the lens of public utility. To further examine how the net neutrality debate is being addressed, and to see the potential impacts of media discourses on the general public, the results of a focus group are reported and analyzed. Finally, a discussion assesses the implications of the net neutrality debate as presented through media discourses, highlighting the future of net neutrality as an important policy issue.

  14. National Energy Balance - 1985

    International Nuclear Information System (INIS)

    Anon.

    1985-01-01

    The National Energy Balance - 1985 shows energy fluxes of several primary and secondary energy sources, since the production to the final consumption in the main economic sectors, since 1974 to 1984 (E.G.) [pt

  15. National Energy Balance - 1984

    International Nuclear Information System (INIS)

    Anon.

    1984-01-01

    The National Energy Balance - 1984 shows energy fluxes of several primary and secondary energy sources, since the productions to final consumption in the main economic sectors, since 1973 to 1983. (E.G.) [pt

  16. Transmission on Balance 2006

    International Nuclear Information System (INIS)

    2007-02-01

    Every year he Dutch Transmission System Operator (TSO) TenneT issues the title publication 'Transmission on Balance'. This report provides information about the main technical operating results in the past year.

  17. The Balanced Literacy Diet.

    Science.gov (United States)

    Willows, Dale

    2002-01-01

    Describes professional development program in Ontario school district to improve student reading and writing skills. Program used food-pyramid concepts to help teacher learn to provide a balanced and flexible approach to literacy instruction based on student needs. (PKP)

  18. National Energy Balance-1987

    International Nuclear Information System (INIS)

    Anon.

    1987-01-01

    The National Energy Balance - 1987 showns energy fluxes of several primary and secondary energy sources, since the production to final consumption in the main economic sectors, since 1971 to 1986. (E.G.) [pt

  19. In Balance With

    Directory of Open Access Journals (Sweden)

    Courtney Kessel

    2013-01-01

    Full Text Available 'In Balance With' (2012 is a live performance with Courtney Kessel and her daughter, Chloé, sitting at opposite ends of a seesaw. During the 30-minute performance, Kessel adds items representative of their lives to Chloé's side of the seesaw. After each group of items is added, she returns to her side to check the balance. Toys, violin, research books, food, pots, tools, and laundry are strapped on to the seesaw. The audience witnesses the struggle to create a balance between work, home, research, and play as a single mother and artist. As equilibrium is achieved, Kessel stills labors to maintain the balance until Chloé is ready to get down, thus signaling that her work can only happen when her daughter is cared for and occupied.

  20. Energy balances 2000

    International Nuclear Information System (INIS)

    Anon.

    2000-01-01

    The energy balances of the Danish Statistical Office are the designation of the goods balances, which are tabulated for each energy article in both physical entities (quantities) and in base rates (values). The balance concept is connected to the definition supply = use, which is the basis for the construction of the system. The supply is determined as the sum of two items: import and production while the total use is the sum of 138 items: export, waste and transmission loss, stock increase, input in lack of the 130 industries, and private consumption divided into 5 consumption groups. The statistical analysis is performed yearly in both quantities and values for 35 energy articles. Values are computed for base rates, profits, taxes, VAT and market prices (buyer's price), respectively. The energy balances from 1975 to 2000 are presented for comparison. (EHS)

  1. Symmetric Cryptosystem Based on Petri Net

    Directory of Open Access Journals (Sweden)

    Hussein ‎ A. Lafta

    2017-12-01

    Full Text Available In this wok, a novel approach based on ordinary Petri net is used to generate private key . The reachability marking  of petri net is used as encryption/decryption key to provide more complex key . The same ordinary Petri Nets models  are used for the sender(encryption and  the receiver(decryption.The plaintext has been permutated  using  look-up table ,and XOR-ed with key to generate cipher text

  2. Characterizing behavioural congruences for Petri nets

    DEFF Research Database (Denmark)

    Nielsen, Mogens; Priese, Lutz; Sassone, Vladimiro

    1995-01-01

    We exploit a notion of interface for Petri nets in order to design a set of net combinators. For such a calculus of nets, we focus on the behavioural congruences arising from four simple notions of behaviour, viz., traces, maximal traces, step, and maximal step traces, and from the corresponding...... four notions of bisimulation, viz., weak and weak step bisimulation and their maximal versions. We characterize such congruences via universal contexts and via games, providing in such a way an understanding of their discerning powers....

  3. Mars MetNet Mission Payload Overview

    Science.gov (United States)

    Harri, A.-M.; Haukka, H.; Alexashkin, S.; Guerrero, H.; Schmidt, W.; Genzer, M.; Vazquez, L.

    2012-09-01

    A new kind of planetary exploration mission for Mars is being developed in collaboration between the Finnish Meteorological Institute (FMI), Lavochkin Association (LA), Space Research Institute (IKI) and Institutio Nacional de Tecnica Aerospacial (INTA). The Mars MetNet mission [1] is based on a new semi-hard landing vehicle called MetNet Lander (MNL). The scientific payload of the Mars MetNet Precursor mission is divided into three categories: Atmospheric instruments, Optical devices and Composition and structure devices. Each of the payload instruments will provide crucial scientific data about the Martian atmospheric phenomena.

  4. The net neutrality debate on Twitter

    Directory of Open Access Journals (Sweden)

    Wolf J. Schünemann

    2015-12-01

    Full Text Available The internet has been seen as a medium that empowers individual political actors in relation to established political elites and media gatekeepers. The present article discusses this “net empowerment hypothesis” and tests it empirically by analysing Twitter communication on the regulation of net neutrality. We extracted 503.839 tweets containing #NetNeutrality posted between January and March 2015 and analysed central developments and the network structure of the debate. The empirical results show that traditional actors from media and politics still maintain a central role.

  5. Visual Studio 2010 and NET 4 Six-in-One

    CERN Document Server

    Novak, Istvan; Granicz, Adam

    2010-01-01

    Complete coverage of all key .NET 4 and Visual Studio 2010 languages and technologies. .NET 4 is Microsoft's latest version of their core programming platform, and Visual Studio 2010 is the toolset that helps write .NET 4 applications. This comprehensive resource offers one-stop shopping for all you need to know to get productive with .NET 4. Experienced author and .NET guru Mitchel Sellers reviews all the important new features of .NET 4, including .NET charting and ASP.NET charting, ASP.NET dynamic data and jQuery, and the addition of F# as a supported package language. The expansive coverag

  6. Balancing beyond the horizon?

    DEFF Research Database (Denmark)

    Kluth, Michael Friederich; Pilegaard, Jess

    2011-01-01

    The present article seeks to make sense of recent European Union (EU) naval capability changes by applying neo-realist theory to the EU as a collective actor in the global balance of power. The paper compares two different strands of neorealist theory by deducing key predictions about the expecte......-term balancing strategy aimed at bolstering the autonomy and international influence of the Union vis-a`-vis other major powers, including the USA....

  7. Greenland Ice Sheet Mass Balance

    Science.gov (United States)

    Reeh, N.

    1984-01-01

    Mass balance equation for glaciers; areal distribution and ice volumes; estimates of actual mass balance; loss by calving of icebergs; hydrological budget for Greenland; and temporal variations of Greenland mass balance are examined.

  8. Balances instruments, manufacturers, history

    CERN Document Server

    Robens, Erich; Kiefer, Susanne

    2014-01-01

    The book deals mainly with direct mass determination by means of a conventional balances. It covers the history of the balance from the beginnings in Egypt earlier than 3000 BC to recent developments. All balance types are described with emphasis on scientific balances. Methods of indirect mass determination, which are applied to very light objects like molecules and the basic particles of matter and celestial bodies, are included.  As additional guidance, today’s manufacturers are listed and the profile of important companies is reviewed. Several hundred photographs, reproductions and drawings show instruments and their uses. This book includes commercial weighing instruments for merchandise and raw materials in workshops as well as symbolic weighing in the ancient Egyptian’s ceremony of ‘Weighing of the Heart’, the Greek fate balance, the Roman  Justitia, Juno Moneta and Middle Ages scenes of the Last Judgement with Jesus or St. Michael and of modern balances. The photographs are selected from the...

  9. Net Pay Estimator | Alaska Division of Retirement and Benefits

    Science.gov (United States)

    Benefits > Net Pay Estimator Online Counselor Scheduler Empower Retirement Account Info Online myRnB Accessibility Net Pay Estimator Click here for the Retiree Net Pay Estimator? The net pay estimator is a useful tool to estimate your net pay under different salaries, federal withholding tax exemptions, and

  10. Studies on the suitability of HDPE material for gill nets

    OpenAIRE

    Subramania Pillai, N.; Boopendranath, M.R.; Kunjipalu, K.K.

    1989-01-01

    The suitability of HDPE yarn and HDPE twine in place of nylon for gill nets has been studied. As regards total catch nylon gill net is found to be better than HDPE nets. However, statistical analysis of the catch in respect of quality fishes shows that HDPE yarn nets are equally efficient as nylon nets.

  11. The Petri Net Markup Language : concepts, technology, and tools

    NARCIS (Netherlands)

    Billington, J.; Christensen, S.; Hee, van K.M.; Kindler, E.; Kummer, O.; Petrucci, L.; Post, R.D.J.; Stehno, C.; Weber, M.; Aalst, van der W.M.P.; Best, E.

    2003-01-01

    The Petri Net Markup Language (PNML) is an XML-based interchange format for Petri nets. In order to support different versions of Petri nets and, in particular, future versions of Petri nets, PNML allows the definition of Petri net types.Due to this flexibility, PNML is a starting point for a

  12. Net present value analysis of the economic production quantity

    OpenAIRE

    Disney, Stephen Michael; Warburton, R. D. H.; Zhong, Q. C.

    2013-01-01

    Using Laplace transforms we extend the economic production quantity (EPQ) model by analysing cash flows from a net present value (NPV) viewpoint. We obtain an exact expression for the present value of the cash flows in the EPQ problem. From this, we are able to derive the optimal batch size. We obtain insights into the monotonicity and convexity of the present value of each of the cash flows, and show that there is a unique minimum in the present value of the sum of the cash flows in the exte...

  13. Sensitivity and uncertainty analysis of NET/ITER shielding blankets

    International Nuclear Information System (INIS)

    Hogenbirk, A.; Gruppelaar, H.; Verschuur, K.A.

    1990-09-01

    Results are presented of sensitivity and uncertainty calculations based upon the European fusion file (EFF-1). The effect of uncertainties in Fe, Cr and Ni cross sections on the nuclear heating in the coils of a NET/ITER shielding blanket has been studied. The analysis has been performed for the total cross section as well as partial cross sections. The correct expression for the sensitivity profile was used, including the gain term. The resulting uncertainty in the nuclear heating lies between 10 and 20 per cent. (author). 18 refs.; 2 figs.; 2 tabs

  14. Climatic Forecasting of Net Infiltration at Yucca Mountain Using Analogue Meteorological Data

    International Nuclear Information System (INIS)

    Faybishenko, Boris

    2005-01-01

    At Yucca Mountain, NV, future changes in climatic conditions will probably alter net infiltration, drainage below the bottom of the evapotranspiration zone within the soil profile, or flow across the interface between soil and the densely welded part of the Tiva Canyon Tuff. The objectives of this study were to: (1) develop a semiempirical model and forecast average net infiltration rates, using the limited meteorological data from analog meteorological stations, for interglacial(present day), and future monsoon, glacial transition, and glacial climates over the Yucca Mountain region; and (2) corroborate the computed net infiltration rates by comparing them with the empirically and numerically determined groundwater recharge and percolation rates through the unsaturated zone from published data. This study approached calculations of net infiltration, aridity, and precipitation effectiveness indices using a modified Budyko's water-balance model, with reference-surface potential evapotranspiration determined from the radiation-based Penman formula. Results of calculations show that net infiltration rates are expected to generally increase from the present-day climate to monsoon climate, to glacial transition climate, and then to the glacial climate, following a power law relationship between net infiltration and precipitation. The forecasting results indicate the overlap between the ranges of net infiltration for different climates. Forecasting of net infiltration for different climate states is subject to numerous uncertainties associated with selecting climate analog sites, using relatively short analog meteorological records, neglecting the effects of vegetation and surface runoff and run-on on a local scale, as well as possible anthropogenically induced climate changes

  15. Chemical processes related to net ozone tendencies in the free troposphere

    Science.gov (United States)

    Bozem, Heiko; Butler, Tim M.; Lawrence, Mark G.; Harder, Hartwig; Martinez, Monica; Kubistin, Dagmar; Lelieveld, Jos; Fischer, Horst

    2017-09-01

    Ozone (O3) is an important atmospheric oxidant, a greenhouse gas, and a hazard to human health and agriculture. Here we describe airborne in situ measurements and model simulations of O3 and its precursors during tropical and extratropical field campaigns over South America and Europe, respectively. Using the measurements, net ozone formation/destruction tendencies are calculated and compared to 3-D chemistry-transport model simulations. In general, observation-based net ozone tendencies are positive in the continental boundary layer and the upper troposphere at altitudes above ˜ 6 km in both environments. On the other hand, in the marine boundary layer and the middle troposphere, from the top of the boundary layer to about 6-8 km altitude, net O3 destruction prevails. The ozone tendencies are controlled by ambient concentrations of nitrogen oxides (NOx). In regions with net ozone destruction the available NOx is below the threshold value at which production and destruction of O3 balance. While threshold NO values increase with altitude, in the upper troposphere NOx concentrations are generally higher due to the integral effect of convective precursor transport from the boundary layer, downward transport from the stratosphere and NOx produced by lightning. Two case studies indicate that in fresh convective outflow of electrified thunderstorms net ozone production is enhanced by a factor 5-6 compared to the undisturbed upper tropospheric background. The chemistry-transport model MATCH-MPIC generally reproduces the pattern of observation-based net ozone tendencies but mostly underestimates the magnitude of the net tendency (for both net ozone production and destruction).

  16. Spectral estimates of net radiation and soil heat flux

    International Nuclear Information System (INIS)

    Daughtry, C.S.T.; Kustas, W.P.; Moran, M.S.; Pinter, P.J. Jr.; Jackson, R.D.; Brown, P.W.; Nichols, W.D.; Gay, L.W.

    1990-01-01

    Conventional methods of measuring surface energy balance are point measurements and represent only a small area. Remote sensing offers a potential means of measuring outgoing fluxes over large areas at the spatial resolution of the sensor. The objective of this study was to estimate net radiation (Rn) and soil heat flux (G) using remotely sensed multispectral data acquired from an aircraft over large agricultural fields. Ground-based instruments measured Rn and G at nine locations along the flight lines. Incoming fluxes were also measured by ground-based instruments. Outgoing fluxes were estimated using remotely sensed data. Remote Rn, estimated as the algebraic sum of incoming and outgoing fluxes, slightly underestimated Rn measured by the ground-based net radiometers. The mean absolute errors for remote Rn minus measured Rn were less than 7%. Remote G, estimated as a function of a spectral vegetation index and remote Rn, slightly overestimated measured G; however, the mean absolute error for remote G was 13%. Some of the differences between measured and remote values of Rn and G are associated with differences in instrument designs and measurement techniques. The root mean square error for available energy (Rn - G) was 12%. Thus, methods using both ground-based and remotely sensed data can provide reliable estimates of the available energy which can be partitioned into sensible and latent heat under non advective conditions

  17. Hairy Graphenes: Wrapping Nanocellulose Nets around Graphene Oxide Sheets.

    Science.gov (United States)

    Xiong, Rui; Kim, Ho Shin; Korolovych, Volodymyr F; Zhang, Shuaidi; Yingling, Yaroslava; Tsukruk, Vladimir V

    2018-04-17

    Constructing advanced functional nanomaterials with pre-designed organized morphologies from low-dimension synthetic and biological components is extremely challenging because of complex inter-component interactions, high-aspect ratios, flexible shapes, crumpling instabilities and limited common wet-chemistry processing conditions. Herein, we report an efficient and universal amphiphilicity-driven assembly strategy to construct "hairy" flexible hybrid nanosheets with the net of 1D cellulose nanofibers (CNFs) conformally wrapped around 2D graphene oxide (GO) monolayers. This interface-driven bio-synthetic assembly is facilitated by variable amphiphilic interfacial balance via tailoring the surface chemistry of flexible GO sheets as controllably pre-oxidized 2D template cores, resulting in individual sheets tightly surrounded by dense conformal nanocellulose network. These nanocellulose-net wrapped GO nanosheets demonstrate extremely high compressive elastic modulus above 180 GPa due to the strong bonding between nanofibers and GO sheets and arrest of the buckling events. This unique mechanical stability far exceeds the compressive instability limits of both individual components, 1D cellulose nanofibers and 2D graphene monolayers. Additionally, the presence of CNF reinforced nanocellulose network significantly enhances the wetting ability of initial hydrophobic reduced GO nanosheets, enabling the long-term stability of CNFs-rGO dispersion and allowing fast water transport combined with high filtration efficiency for CNFs-rGO membranes. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Net Zero Energy Military Installations: A Guide to Assessment and Planning

    Energy Technology Data Exchange (ETDEWEB)

    Booth, S.; Barnett, J.; Burman, K.; Hambrick, J.; Westby, R.

    2010-08-01

    The U.S. Department of Defense (DoD) recognizes the strategic importance of energy to its mission, and is working to reduce energy consumption and enhance energy self-sufficiency by drawing on local clean energy sources. A joint initiative formed between DoD and the U.S. Department of Energy (DOE) in 2008 to address military energy use led to a task force to examine the potential for net zero energy military installations, which would produce as much energy on site as they consume in buildings, facilities, and fleet vehicles. This report presents an assessment and planning process to examine military installations for net zero energy potential. Net Zero Energy Installation Assessment (NZEIA) presents a systematic framework to analyze energy projects at installations while balancing other site priorities such as mission, cost, and security.

  19. Sumoylation of the net inhibitory domain (NID) is stimulated by PIAS1 and has a negative effect on the transcriptional activity of Net.

    Science.gov (United States)

    Wasylyk, Christine; Criqui-Filipe, Paola; Wasylyk, Bohdan

    2005-01-27

    Net (Elk-3, Sap-2, Erp) and the related ternary complex factors Elk-1 and Sap-1 are effectors of multiple signalling pathways at the transcriptional level and play a key role in the dynamic regulation of gene expression. Net is distinct from Elk-1 and Sap-1, in that it is a strong repressor of transcription that is converted to an activator by the Ras/Erk signalling pathway. Two autonomous repression domains of Net, the NID and the CID, mediate repression. We have previously shown that the co-repressor CtBP is implicated in repression by the CID. In this report we show that repression by the NID involves a different pathway, sumoylation by Ubc9 and PIAS1. PIAS1 interacts with the NID in the two-hybrid assay and in vitro. Ubc9 and PIAS1 stimulate sumoylation in vivo of lysine 162 in the NID. Sumoylation of lysine 162 increases repression by Net and decreases the positive activity of Net. These results increase our understanding of how one of the ternary complex factors regulates transcription, and contribute to the understanding of how different domains of a transcription factor participate in the complexity of regulation of gene expression.

  20. Field-scale water balance closure in seasonally frozen conditions

    Directory of Open Access Journals (Sweden)

    X. Pan

    2017-11-01

    Full Text Available Hydrological water balance closure is a simple concept, yet in practice it is uncommon to measure every significant term independently in the field. Here we demonstrate the degree to which the field-scale water balance can be closed using only routine field observations in a seasonally frozen prairie pasture field site in Saskatchewan, Canada. Arrays of snow and soil moisture measurements were combined with a precipitation gauge and flux tower evapotranspiration estimates. We consider three hydrologically distinct periods: the snow accumulation period over the winter, the snowmelt period in spring, and the summer growing season. In each period, we attempt to quantify the residual between net precipitation (precipitation minus evaporation and the change in field-scale storage (snow and soil moisture, while accounting for measurement uncertainties. When the residual is negligible, a simple 1-D water balance with no net drainage is adequate. When the residual is non-negligible, we must find additional processes to explain the result. We identify the hydrological fluxes which confound the 1-D water balance assumptions during different periods of the year, notably blowing snow and frozen soil moisture redistribution during the snow accumulation period, and snowmelt runoff and soil drainage during the melt period. Challenges associated with quantifying these processes, as well as uncertainties in the measurable quantities, caution against the common use of water balance residuals to estimate fluxes and constrain models in such a complex environment.

  1. Kisspeptin and energy balance in reproduction.

    Science.gov (United States)

    De Bond, Julie-Ann P; Smith, Jeremy T

    2014-03-01

    Kisspeptin is vital for the neuroendocrine regulation of GNRH secretion. Kisspeptin neurons are now recognized as a central pathway responsible for conveying key homeostatic information to GNRH neurons. This pathway is likely to mediate the well-established link between energy balance and reproductive function. Thus, in states of severely altered energy balance (either negative or positive), fertility is compromised, as is Kiss1 expression in the arcuate nucleus. A number of metabolic modulators have been proposed as regulators of kisspeptin neurons including leptin, ghrelin, pro-opiomelanocortin (POMC), and neuropeptide Y (NPY). Whether these regulate kisspeptin neurons directly or indirectly will be discussed. Moreover, whether the stimulatory role of leptin on reproduction is mediated by kisspeptin directly will be questioned. Furthermore, in addition to being expressed in GNRH neurons, the kisspeptin receptor (Kiss1r) is also expressed in other areas of the brain, as well as in the periphery, suggesting alternative roles for kisspeptin signaling outside of reproduction. Interestingly, kisspeptin neurons are anatomically linked to, and can directly excite, anorexigenic POMC neurons and indirectly inhibit orexigenic NPY neurons. Thus, kisspeptin may have a direct role in regulating energy balance. Although data from Kiss1r knockout and WT mice found no differences in body weight, recent data indicate that kisspeptin may still play a role in food intake and glucose homeostasis. Thus, in addition to regulating reproduction, and mediating the effect of energy balance on reproductive function, kisspeptin signaling may also be a direct regulator of metabolism.

  2. Mars MetNet Mission Status

    Science.gov (United States)

    Harri, A.-M.; Aleksashkin, S.; Arruego, I.; Schmidt, W.; Genzer, M.; Vazquez, L.; Haukka, H.; Palin, M.; Nikkanen, T.

    2015-10-01

    New kind of planetary exploration mission for Mars is under development in collaboration between the Finnish Meteorological Institute (FMI), Lavochkin Association (LA), Space Research Institute (IKI) and Institutio Nacional de Tecnica Aerospacial (INTA). The Mars MetNet mission is based on a new semihard landing vehicle called MetNet Lander (MNL). The scientific payload of the Mars MetNet Precursor [1] mission is divided into three categories: Atmospheric instruments, Optical devices and Composition and structure devices. Each of the payload instruments will provide significant insights in to the Martian atmospheric behavior. The key technologies of the MetNet Lander have been qualified and the electrical qualification model (EQM) of the payload bay has been built and successfully tested.

  3. Mars MetNet Precursor Mission Status

    Science.gov (United States)

    Harri, A.-M.; Aleksashkin, S.; Guerrero, H.; Schmidt, W.; Genzer, M.; Vazquez, L.; Haukka, H.

    2013-09-01

    We are developing a new kind of planetary exploration mission for Mars in collaboration between the Finnish Meteorological Institute (FMI), Lavochkin Association (LA), Space Research Institute (IKI) and Institutio Nacional de Tecnica Aerospacial (INTA). The Mars MetNet mission is based on a new semi-hard landing vehicle called MetNet Lander (MNL). The scientific payload of the Mars MetNet Precursor [1] mission is divided into three categories: Atmospheric instruments, Optical devices and Composition and structure devices. Each of the payload instruments will provide significant insights in to the Martian atmospheric behavior. The key technologies of the MetNet Lander have been qualified and the electrical qualification model (EQM) of the payload bay has been built and successfully tested.

  4. RadNet Air Quality (Deployable) Data

    Data.gov (United States)

    U.S. Environmental Protection Agency — RadNet Deployable Monitoring is designed to collect radiological and meteorological information and data asset needed to establish the impact of radiation levels on...

  5. Versatile Wireless Data Net, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The proposed R many will be MEMS devices. The net enables coordinated, efficient transmission of measurement signals; self test metrics, and environmental metrics to...

  6. Integrating phenotype ontologies with PhenomeNET

    KAUST Repository

    Rodriguez-Garcia, Miguel Angel; Gkoutos, Georgios V.; Schofield, Paul N.; Hoehndorf, Robert

    2017-01-01

    in clinical and model organism databases presents complex problems when attempting to match classes across species and across phenotypes as diverse as behaviour and neoplasia. We have previously developed PhenomeNET, a system for disease gene prioritization

  7. The Uniframe .Net Web Service Discovery Service

    National Research Council Canada - National Science Library

    Berbeco, Robert W

    2003-01-01

    ...) and registered with Internet Information Server (IIS), and can be applied in numerous fashions This project uses the NET capabilities to create a distributed discovery service (called as UNWSDS...

  8. Elliptic net and its cryptographic application

    Science.gov (United States)

    Muslim, Norliana; Said, Mohamad Rushdan Md

    2017-11-01

    Elliptic net is a generalization of elliptic divisibility sequence and in cryptography field, most cryptographic pairings that are based on elliptic curve such as Tate pairing can be improved by applying elliptic nets algorithm. The elliptic net is constructed by using n dimensional array of values in rational number satisfying nonlinear recurrence relations that arise from elliptic divisibility sequences. The two main properties hold in the recurrence relations are for all positive integers m>n, hm +nhm -n=hm +1hm -1hn2-hn +1hn -1hm2 and hn divides hm whenever n divides m. In this research, we discuss elliptic divisibility sequence associated with elliptic nets based on cryptographic perspective and its possible research direction.

  9. A Lightweight TwiddleNet Portal

    National Research Council Canada - National Science Library

    Rimikis, Antonios M

    2008-01-01

    TwiddleNet is a distributed architecture of personal servers that harnesses the power of the mobile devices, enabling real time information and file sharing of multiple data types from commercial-off-the-shelf platforms...

  10. Counterintuitive proposals for trans-boundary ecological compensation under "No Net Loss" biodiversity policy

    DEFF Research Database (Denmark)

    Bull, Joseph William; Abatayo, Anna Lou; Strange, Niels

    2017-01-01

    ‘No net loss’ (NNL) policies involve quantifying biodiversity impacts associated with economic development, and implementing commensurate conservation gains to balance losses. Local stakeholders are often affected by NNL biodiversity trades. But to what extent are NNL principles intuitive...... compensation should be: close to development impacts; greater than losses; smaller, given a background trend of biodiversity decline; and, smaller when gains have co-benefits for biodiversity. However, survey participant proposals violated all four principles. Participants proposed substantial forest...

  11. MMPM - Mars MetNet Precursor Mission

    Science.gov (United States)

    Harri, A.-M.; Schmidt, W.; Pichkhadze, K.; Linkin, V.; Vazquez, L.; Uspensky, M.; Polkko, J.; Genzer, M.; Lipatov, A.; Guerrero, H.; Alexashkin, S.; Haukka, H.; Savijarvi, H.; Kauhanen, J.

    2008-09-01

    We are developing a new kind of planetary exploration mission for Mars - MetNet in situ observation network based on a new semi-hard landing vehicle called the Met-Net Lander (MNL). The eventual scope of the MetNet Mission is to deploy some 20 MNLs on the Martian surface using inflatable descent system structures, which will be supported by observations from the orbit around Mars. Currently we are working on the MetNet Mars Precursor Mission (MMPM) to deploy one MetNet Lander to Mars in the 2009/2011 launch window as a technology and science demonstration mission. The MNL will have a versatile science payload focused on the atmospheric science of Mars. Detailed characterization of the Martian atmospheric circulation patterns, boundary layer phenomena, and climatology cycles, require simultaneous in-situ measurements by a network of observation posts on the Martian surface. The scientific payload of the MetNet Mission encompasses separate instrument packages for the atmospheric entry and descent phase and for the surface operation phase. The MetNet mission concept and key probe technologies have been developed and the critical subsystems have been qualified to meet the Martian environmental and functional conditions. Prototyping of the payload instrumentation with final dimensions was carried out in 2003-2006.This huge development effort has been fulfilled in collaboration between the Finnish Meteorological Institute (FMI), the Russian Lavoschkin Association (LA) and the Russian Space Research Institute (IKI) since August 2001. Currently the INTA (Instituto Nacional de Técnica Aeroespacial) from Spain is also participating in the MetNet payload development. To understand the behavior and dynamics of the Martian atmosphere, a wealth of simultaneous in situ observations are needed on varying types of Martian orography, terrain and altitude spanning all latitudes and longitudes. This will be performed by the Mars MetNet Mission. In addition to the science aspects the

  12. .NET 4.5 parallel extensions

    CERN Document Server

    Freeman, Bryan

    2013-01-01

    This book contains practical recipes on everything you will need to create task-based parallel programs using C#, .NET 4.5, and Visual Studio. The book is packed with illustrated code examples to create scalable programs.This book is intended to help experienced C# developers write applications that leverage the power of modern multicore processors. It provides the necessary knowledge for an experienced C# developer to work with .NET parallelism APIs. Previous experience of writing multithreaded applications is not necessary.

  13. Mastering AngularJD for .NET developers

    CERN Document Server

    Majid, Mohammad Wadood

    2015-01-01

    This book is envisioned for traditional developers and programmers who want to develop client-side applications using the AngularJS framework and ASP.NET Web API 2 with Visual Studio. .NET developers who have already built web applications or web services and who have a fundamental knowledge of HTML, JavaScript, and CSS and want to explore single-page applications will also find this guide useful. Basic knowledge of AngularJS would be helpful.

  14. CCS - and its relationship to net theory

    DEFF Research Database (Denmark)

    Nielsen, Mogens

    1987-01-01

    In this paper we give a short introduction to Milner's Calculus for Communicating Systems - a paradigm for concurrent computation. We put special emphasis on the basic concepts and tools from the underlying "algebraic approach", and their relationship to the approach to concurrency within net the...... theory. Furthermore, we provide an operational version of the language CCS with "true concurrency" in the sense of net theory, and a discussion of the possible use of such a marriage of the two theories of concurrency....

  15. Control of Petri Nets by finite automata

    Energy Technology Data Exchange (ETDEWEB)

    Burkhard, H D

    1983-01-01

    Petri Nets are considered where the firings are controlled by finite automata. The control may be distributed to various automata working over disjoint sets of transitions. To avoid deadlocks and conflicts for the whole system the distribution of control must be organised in an appropriate manner. The existence of deadlocks and conflicts is shown to be undecidable in general, but conflict resolving and deadlock free controls can be constructed for given nets. 10 references.

  16. An investigation of energy balances in palladium cathode electrolysis experiments

    Science.gov (United States)

    Longhurst, G. R.; Dolan, T. J.; Henriksen, G. L.

    1990-09-01

    A series of experiments was performed at the Idaho National Engineering Laboratory (INEL) to investigate mechanisms that may contribute to energy flows in electrolysis cells like those of Fleischmann and Pons. Ordinary water (H2O), heavy water (D2O), and a mixture of the two were used in the INEL experiments. Cathodes used include a 51-μm Pd foil and 1-mm diameter extruded wire Pd rods in straight and coiled configurations. Energy balances in these experiments revealed no significant net gain or net loss of energy. Cell overpotential curves were fit well with a Tafel equation, with parameters dependent on electrode configuration, electrolyte composition, and temperature. Water evaporation and interactions of hydrogen isotopes with the Pd cathode were evaluated and found not to be significant to energy balances. No ionizing radiation, tritium production, or other evidence of fusion reactions was observed in the INEL experiments.

  17. Neutrophil NETs in reproduction: from infertility to preeclampsia and the possibility of fetal loss

    Directory of Open Access Journals (Sweden)

    Sinuhe eHahn

    2012-11-01

    Full Text Available The intention of this review is to provide an overview of the potential role of neutrophil extracellular traps (NETs in mammalian reproduction. Neutrophil NETs appear to be involved in various stages of the reproductive cycle, starting with fertility and possibly ending with fetal loss. The first suggestion that NETs may play a role in pregnancy-related disorders was in preeclampsia, where vast numbers were detected in the intervillous space of affected placentae. The induction of NETosis involved an auto-inflammatory component, mediated by the increased release of placental micro-debris in preeclampsia. This report was the first indicating that NETs may be associated with a human pathology not involving infection.Subsequently, NETs have since then been implicated in bovine or equine infertility, in that semen may become entrapped in the female reproductive during their passage to the oocyte. In this instance interesting species-specific differences are apparent, in that equine sperm evade entrapment via expression of a DNAse-like molecule, whereas highly motile bovine sperm, once free from seminal plasma that promotes interaction with neutrophils, appear impervious to NETs entrapment.Although still in the realm of speculation it is plausible that NETs may be involved in recurrent fetal loss mediated by anti-phospholipid antibodies, or perhaps even in fetal abortion triggered by infections with microorganisms such as L. monocytogenes or B. abortus.

  18. Systems principles of planning the net cost of oil and gas extraction

    Energy Technology Data Exchange (ETDEWEB)

    Ryazanova, N I

    1979-01-01

    The automated system of calculation of ASPC ''oil extraction'' is developed in order to improve the existing system of planning of the oil extracting sector. The most complete expression of the systems construction of the plan is found in the section ''net cost and profit.'' Unity of the production process advances definite requirements for construction of the plan for net cost of oil and gas extraction as the model of this unified process. According to these requirements, the plan for net cost must be developed on the basis of interrelationship of the indicators of the plan for net cost within the section and with indicators of other sections of the plan, methodological unity and continuity of the methods of planning net cost by elements of outlays, articles of calculation and technical-economic factors, methodological continuity of regimes and stages of planning, as well as based on methodological continuity of the control levels. The listed requirements are principles for systems planning of the net cost of oil and gas extraction. These principles guarantee improvement in planning of net cost of oil and gas extraction according to the requirements made for the national economic planning.

  19. A balanced ATP driving force module for enhancing photosynthetic biosynthesis of 3-hydroxybutyrate from CO2.

    Science.gov (United States)

    Ku, Jason T; Lan, Ethan I

    2018-03-01

    Using engineered photoautotrophic microorganisms for the direct chemical synthesis from CO 2 is an attractive direction for both sustainability and CO 2 mitigation. However, the behaviors of non-native metabolic pathways may be difficult to control due to the different intracellular contexts between natural and heterologous hosts. While most metabolic engineering efforts focus on strengthening driving forces in pathway design to favor biochemical production in these organisms, excessive driving force may be detrimental to product biosynthesis due to imbalanced cellular intermediate distribution. In this study, an ATP-hydrolysis based driving force module was engineered into cyanobacterium Synechococcus elongatus PCC 7942 to produce 3-hydroxybutyrate (3HB), a valuable chemical feedstock for the synthesis of biodegradable plastics and antibiotics. However, while the ATP driving force module is effective for increasing product formation, uncontrolled accumulation of intermediate metabolites likely led to metabolic imbalance and thus to cell growth inhibition. Therefore, the ATP driving force module was reengineered by providing a reversible outlet for excessive carbon flux. Upon expression of this balanced ATP driving force module with 3HB biosynthesis, engineered strain produced 3HB with a cumulative titer of 1.2 g/L, a significant increase over the initial strain. This result highlighted the importance of pathway reversibility as an effective design strategy for balancing driving force and intermediate accumulation, thereby achieving a self-regulated control for increased net flux towards product biosynthesis. Copyright © 2018 International Metabolic Engineering Society. Published by Elsevier Inc. All rights reserved.

  20. UV sensitivity of planktonic net community production in ocean surface waters

    Science.gov (United States)

    Regaudie-de-Gioux, Aurore; Agustí, Susana; Duarte, Carlos M.

    2014-05-01

    The net plankton community metabolism of oceanic surface waters is particularly important as it more directly affects the partial pressure of CO2 in surface waters and thus the air-sea fluxes of CO2. Plankton communities in surface waters are exposed to high irradiance that includes significant ultraviolet blue (UVB, 280-315 nm) radiation. UVB radiation affects both photosynthetic and respiration rates, increase plankton mortality rates, and other metabolic and chemical processes. Here we test the sensitivity of net community production (NCP) to UVB of planktonic communities in surface waters across contrasting regions of the ocean. We observed here that UVB radiation affects net plankton community production at the ocean surface, imposing a shift in NCP by, on average, 50% relative to the values measured when excluding partly UVB. Our results show that under full solar radiation, the metabolic balance shows the prevalence of net heterotrophic community production. The demonstration of an important effect of UVB radiation on NCP in surface waters presented here is of particular relevance in relation to the increased UVB radiation derived from the erosion of the stratospheric ozone layer. Our results encourage design future research to further our understanding of UVB effects on the metabolic balance of plankton communities.

  1. Inferring Phylogenetic Networks Using PhyloNet.

    Science.gov (United States)

    Wen, Dingqiao; Yu, Yun; Zhu, Jiafan; Nakhleh, Luay

    2018-07-01

    PhyloNet was released in 2008 as a software package for representing and analyzing phylogenetic networks. At the time of its release, the main functionalities in PhyloNet consisted of measures for comparing network topologies and a single heuristic for reconciling gene trees with a species tree. Since then, PhyloNet has grown significantly. The software package now includes a wide array of methods for inferring phylogenetic networks from data sets of unlinked loci while accounting for both reticulation (e.g., hybridization) and incomplete lineage sorting. In particular, PhyloNet now allows for maximum parsimony, maximum likelihood, and Bayesian inference of phylogenetic networks from gene tree estimates. Furthermore, Bayesian inference directly from sequence data (sequence alignments or biallelic markers) is implemented. Maximum parsimony is based on an extension of the "minimizing deep coalescences" criterion to phylogenetic networks, whereas maximum likelihood and Bayesian inference are based on the multispecies network coalescent. All methods allow for multiple individuals per species. As computing the likelihood of a phylogenetic network is computationally hard, PhyloNet allows for evaluation and inference of networks using a pseudolikelihood measure. PhyloNet summarizes the results of the various analyzes and generates phylogenetic networks in the extended Newick format that is readily viewable by existing visualization software.

  2. Improvements to water use and water stress estimates with the addition of IR and net radiometers to weather stations

    Science.gov (United States)

    Evapotranspiration (ET) is often estimated with the Penman-Monteith (P-M) equation. Net radiation (Rn) is a major component of the surface energy balance and an input to the P-M equation, but it is challenging and expensive to measure accurately. For these reasons, most weather stations do not inclu...

  3. Visual Studio 2013 and .NET 4.5 expert cookbook

    CERN Document Server

    Sur, Abhishek

    2014-01-01

    If you are a Visual Studio 2013 or .NET developer who would like to sharpen your existing skill set and adapt to new .NET technologies, this is the book for you. A basic understanding of .NET and C# is required.

  4. HANPP Collection: Global Patterns in Net Primary Productivity (NPP)

    Data.gov (United States)

    National Aeronautics and Space Administration — The Global Patterns in Net Primary Productivity (NPP) portion of the Human Appropriation of Net Primary Productivity (HANPP) Collection maps the net amount of solar...

  5. Time Extensions of Petri Nets for Modelling and Verification of Hard Real-Time Systems

    Directory of Open Access Journals (Sweden)

    Tomasz Szmuc

    2002-01-01

    Full Text Available The main aim ofthe paper is a presentation of time extensions of Petri nets appropriate for modelling and analysis of hard real-time systems. It is assumed, that the extensions must provide a model of time flow an ability to force a transition to fire within a stated timing constraint (the so-called the strong firing rule, and timing constraints represented by intervals. The presented survey includes extensions of classical Place/Transition Petri nets, as well as the ones applied to high-level Petri nets. An expressiveness of each time extension is illustrated using simple hard real-time system. The paper includes also a brief description of analysis and veryication methods related to the extensions, and a survey of software tools supporting modelling and analysis ofthe considered Petri nets.

  6. An Efficient Translation of Timed-Arc Petri Nets to Networks of Timed Automata

    DEFF Research Database (Denmark)

    Byg, Joakim; Jørgensen, Kenneth Yrke; Srba, Jiri

    2009-01-01

    Bounded timed-arc Petri nets with read-arcs were recently proven equivalent to networks of timed automata, though the Petri net model cannot express urgent behaviour and the described mutual trans- lations are rather inefficient. We propose an extension of timed-arc Petri nets with invariants...... to enforce urgency and with transport arcs to generalise the read-arcs. We also describe a novel translation from the extended timed-arc Petri net model to networks of timed automata. The translation is implemented in the tool TAPAAL and it uses UPPAAL as the verification engine. Our experiments confirm...... the efficiency of the translation and in some cases the translated models verify significantly faster than the native UPPAAL models do....

  7. Soy-dairy protein blend and whey protein ingestion after resistance exercise increases amino acid transport and transporter expression in human skeletal muscle

    Science.gov (United States)

    Reidy, P. T.; Walker, D. K.; Dickinson, J. M.; Gundermann, D. M.; Drummond, M. J.; Timmerman, K. L.; Cope, M. B.; Mukherjea, R.; Jennings, K.; Volpi, E.

    2014-01-01

    Increasing amino acid availability (via infusion or ingestion) at rest or postexercise enhances amino acid transport into human skeletal muscle. It is unknown whether alterations in amino acid availability, from ingesting different dietary proteins, can enhance amino acid transport rates and amino acid transporter (AAT) mRNA expression. We hypothesized that the prolonged hyperaminoacidemia from ingesting a blend of proteins with different digestion rates postexercise would enhance amino acid transport into muscle and AAT expression compared with the ingestion of a rapidly digested protein. In a double-blind, randomized clinical trial, we studied 16 young adults at rest and after acute resistance exercise coupled with postexercise (1 h) ingestion of either a (soy-dairy) protein blend or whey protein. Phenylalanine net balance and transport rate into skeletal muscle were measured using stable isotopic methods in combination with femoral arteriovenous blood sampling and muscle biopsies obtained at rest and 3 and 5 h postexercise. Phenylalanine transport into muscle and mRNA expression of select AATs [system L amino acid transporter 1/solute-linked carrier (SLC) 7A5, CD98/SLC3A2, system A amino acid transporter 2/SLC38A2, proton-assisted amino acid transporter 1/SLC36A1, cationic amino acid transporter 1/SLC7A1] increased to a similar extent in both groups (P protein blend resulted in a prolonged and positive net phenylalanine balance during postexercise recovery compared with whey protein (P protein synthesis increased similarly between groups. We conclude that, while both protein sources enhanced postexercise AAT expression, transport into muscle, and myofibrillar protein synthesis, postexercise ingestion of a protein blend results in a slightly prolonged net amino acid balance across the leg compared with whey protein. PMID:24699854

  8. Econometric modeling of the balance of social security Brazil

    OpenAIRE

    Isaac Figueiredo de Sousa

    2009-01-01

    This work aims to build models using econometrics techniques to explain the components of the balance of Social Security System, or in other words, the net value of tax revenues and the benefit values of the General Regime of Social Security. These models were subjected to statistic validations indicated in the theoretical reference of econometrics, to apply the method of ordinary least square from the classic model of linear regression. From an increasing longevity and the gradual decr...

  9. ASP.NET web API build RESTful web applications and services on the .NET framework

    CERN Document Server

    Kanjilal, Joydip

    2013-01-01

    This book is a step-by-step, practical tutorial with a simple approach to help you build RESTful web applications and services on the .NET framework quickly and efficiently.This book is for ASP.NET web developers who want to explore REST-based services with C# 5. This book contains many real-world code examples with explanations whenever necessary. Some experience with C# and ASP.NET 4 is expected.

  10. A Cellular Approach to Net-Zero Energy Cities

    Directory of Open Access Journals (Sweden)

    Miguel Amado

    2017-11-01

    Full Text Available Recent growth in the use of photovoltaic technology and a rapid reduction in its cost confirms the potential of solar power on a large scale. In this context, planning for the deployment of smart grids is among the most important challenges to support the increased penetration of solar energy in urban areas and to ensure the resilience of the electricity system. As part this effort, the present paper describes a cellular approach to a Net-Zero energy concept, based on the balance between the potential solar energy supply and the existing consumption patterns at the urban unit scale. To do that, the Geographical Urban Units Delimitation model (GUUD has been developed and tested on a case study. By applying the GUUD model, which combines Geographic Information Systems (GIS, parametric modelling, and solar dynamic analysis, the whole area of the city was divided into urban cells, categorized as solar producers and energy consumers. The discussion around three theoretical scenarios permits us to explore how smart grids can be approached and promoted from an urban planning perspective. The paper provides insights into how urban planning can be a driver to optimize and manage energy balance across the city if the deployment of smart grids is correctly integrated in its operative process.

  11. Generating a positive energy balance from using rice straw for anaerobic digestion

    Directory of Open Access Journals (Sweden)

    V.H. Nguyen

    2016-11-01

    The net energy of the rice straw supply chain for biogas generation through AD is 3,500 MJ per ton of straw. This rice straw management option can provide a 70% net output energy benefit. The research highlighted the potential of rice straw as a clean fuel source with a positive energy balance, helping to reduce greenhouse gas emissions compared with the existing practice of burning it in the field.

  12. Interchangeability of the Wii Balance Board for Bipedal Balance Assessment

    OpenAIRE

    Bonnech?re, Bruno; Jansen, Bart; Omelina, Lubos; Rooze, Marcel; Van Sint Jan, Serge

    2015-01-01

    Background Since 2010, an increasing interest in more portable and flexible hardware for balance and posture assessment led to previously published studies determining whether or not the Wii Balance Board could be used to assess balance and posture, both scientifically and clinically. However, no previous studies aimed at comparing results from different Wii Balance Boards for clinical balance evaluation exist. Objective The objective of this crossover study is to assess the interchangeabilit...

  13. Balanced articulated manipulator

    International Nuclear Information System (INIS)

    Francois, Daniel; Germond, J.-C.; Marchal, Paul; Vertut, Jean.

    1976-01-01

    The description is given of a manipulator of the type comprising a master arm and a slave arm, capable of working in a containment restricted by a wall fitted with an aperture to introduce the slave arm into the containment. According to the invention this manipulator is permanently balanced irrespective of its distortions when it is secured to the wall of the containment in which it is desired to work. The entire manipulator is also balanced when being set up and when moved outside the containment, in relation to a supporting axle. This result is achieved in a simplified manner by giving homothetic shapes to the various component parts of the slave and master arms, the master arm having at least one balancing weight [fr

  14. Balancing trust and power

    DEFF Research Database (Denmark)

    Broholm-Jørgensen, Marie; Guassora, Ann Dorrit; Reventlow, Susanne

    2017-01-01

    Objective: Little is known about how strategies of retaining patients are acted out by general practitioners (GPs) in the clinical encounter. With this study, we apply Grimens’ (2009) analytical connection between trust and power to explore how trust and power appear in preventive health checks...... of clinical encounters. Results: From the empirical data, we identified three dimensions of respect: respect for the patient’s autonomy, respect for professional authority and respect as a mutual exchange. A balance of respect influenced trust in the relationship between GP and patients and the transfer...... of power in the encounter. The GPs articulated that a balance was needed in preventive health checks in order to establish trust and thus retain the patient in the clinic. One way this balance of respect was carried out was with the use of humour. Conclusions: To retain patients without formal education...

  15. Energy balance of Georgia

    Directory of Open Access Journals (Sweden)

    Demur Chomakhidze

    2016-09-01

    It is shown that, traditionally, the energy balance of Georgia is in deep deficit. The suggestions for its improvement are provided in the Article. The country imports almost all amount of oil and natural gas. Electricity balance is relatively stable. In the recent years, some amount of electricity is exported to the neighboring countries. Generally, the country satisfies only 30–35% of own energy consumption by local generation, and the rest amount of resources are imported from abroad. The reason of deficit to some extent is irrational and wasteful consumption of energy resources. The article examines the organizational difficulties in drawing up energy balance of Georgia and statistical problems of recording of energy production and consumption at the initial stage of market economy.

  16. Net reclassification index at event rate: properties and relationships.

    Science.gov (United States)

    Pencina, Michael J; Steyerberg, Ewout W; D'Agostino, Ralph B

    2017-12-10

    The net reclassification improvement (NRI) is an attractively simple summary measure quantifying improvement in performance because of addition of new risk marker(s) to a prediction model. Originally proposed for settings with well-established classification thresholds, it quickly extended into applications with no thresholds in common use. Here we aim to explore properties of the NRI at event rate. We express this NRI as a difference in performance measures for the new versus old model and show that the quantity underlying this difference is related to several global as well as decision analytic measures of model performance. It maximizes the relative utility (standardized net benefit) across all classification thresholds and can be viewed as the Kolmogorov-Smirnov distance between the distributions of risk among events and non-events. It can be expressed as a special case of the continuous NRI, measuring reclassification from the 'null' model with no predictors. It is also a criterion based on the value of information and quantifies the reduction in expected regret for a given regret function, casting the NRI at event rate as a measure of incremental reduction in expected regret. More generally, we find it informative to present plots of standardized net benefit/relative utility for the new versus old model across the domain of classification thresholds. Then, these plots can be summarized with their maximum values, and the increment in model performance can be described by the NRI at event rate. We provide theoretical examples and a clinical application on the evaluation of prognostic biomarkers for atrial fibrillation. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  17. Pro ASP.NET 4 in VB 2010

    CERN Document Server

    MacDonald, Matthew; Freeman, Adam; Szpuszta, Mario; Agarwal, Vidya Vrat

    2010-01-01

    ASP.NET 4 is the latest version of Microsoft's revolutionary ASP.NET technology. It is the principal standard for creating dynamic web pages on the Windows platform. Pro ASP.NET 4 in VB 2010 raises the bar for high-quality, practical advice on learning and deploying Microsoft's dynamic web solution. This new edition is updated with everything you need to come to grips with the latest version of ASP.NET, including coverage of ASP.NET MVC, ASP.NET AJAX 4, ASP.NET Dynamic Data, and Silverlight 3. Seasoned .NET professionals Matthew MacDonald and Mario Szpuszta explain how you can get the most fro

  18. Sport-specific balance.

    Science.gov (United States)

    Zemková, Erika

    2014-05-01

    This review includes the latest findings based on experimental studies addressing sport-specific balance, an area of research that has grown dramatically in recent years. The main objectives of this work were to investigate the postural sway response to different forms of exercise under laboratory and sport-specific conditions, to examine how this effect can vary with expertise, and to provide examples of the association of impaired balance with sport performance and/or increasing risk of injury. In doing so, sports where body balance is one of the limiting factors of performance were analyzed. While there are no significant differences in postural stability between athletes of different specializations and physically active individuals during standing in a standard upright position (e.g., bipedal stance), they have a better ability to maintain balance in specific conditions (e.g., while standing on a narrow area of support). Differences in magnitude of balance impairment after specific exercises (rebound jumps, repeated rotations, etc.) and mainly in speed of its readjustment to baseline are also observed. Besides some evidence on an association of greater postural sway with the increasing risk of injuries, there are many myths related to the negative influence of impaired balance on sport performance. Though this may be true for shooting or archery, findings have shown that in many other sports, highly skilled athletes are able to perform successfully in spite of increased postural sway. These findings may contribute to better understanding of the postural control system under various performance requirements. It may provide useful knowledge for designing training programs for specific sports.

  19. CellNet: network biology applied to stem cell engineering.

    Science.gov (United States)

    Cahan, Patrick; Li, Hu; Morris, Samantha A; Lummertz da Rocha, Edroaldo; Daley, George Q; Collins, James J

    2014-08-14

    Somatic cell reprogramming, directed differentiation of pluripotent stem cells, and direct conversions between differentiated cell lineages represent powerful approaches to engineer cells for research and regenerative medicine. We have developed CellNet, a network biology platform that more accurately assesses the fidelity of cellular engineering than existing methodologies and generates hypotheses for improving cell derivations. Analyzing expression data from 56 published reports, we found that cells derived via directed differentiation more closely resemble their in vivo counterparts than products of direct conversion, as reflected by the establishment of target cell-type gene regulatory networks (GRNs). Furthermore, we discovered that directly converted cells fail to adequately silence expression programs of the starting population and that the establishment of unintended GRNs is common to virtually every cellular engineering paradigm. CellNet provides a platform for quantifying how closely engineered cell populations resemble their target cell type and a rational strategy to guide enhanced cellular engineering. Copyright © 2014 Elsevier Inc. All rights reserved.

  20. Yin-Yang Balancing

    DEFF Research Database (Denmark)

    Li, Peter Ping

    The potential contribution of the Eastern frame of Yin-Yang Balancing lies in the mindset of "either/and", in contrast to Aristotle's either/or logic and Hegel's "both/or". Implications of this either/and thinking for science and management will be explored.......The potential contribution of the Eastern frame of Yin-Yang Balancing lies in the mindset of "either/and", in contrast to Aristotle's either/or logic and Hegel's "both/or". Implications of this either/and thinking for science and management will be explored....

  1. Finding Your Balance

    CERN Document Server

    (CCL), Center for Creative Leadership; Patterson, Gordon

    2011-01-01

    Balance isn't an issue of time, but an issue of choice. It's about living your values by aligning your behavior with what you believe is really important. Aligning your behavior with your values is much like any other developmental experience; the basic process involves assessment, challenge, and support. You need to determine where you are, define where you want to go, and then put into place the tools you need to get there.Balance is about more than how you spend your time. It's about how you live your life. It's about recognizing that you have control over the choices you make and aligning

  2. Application of Balanced Scorecard

    OpenAIRE

    Langpaulová, Irena

    2011-01-01

    The concept of the Balanced Scorecard taking a part in the strategic management of a company, is a main focus of this thesis. There are the theoretical and methodological parts of the Balanced Scorecard characterized individually, as well as the development and the history of this concept. This thesis is dealing with a draft of the practical implementation of the mentioned methods. The practical part of the thesis is following the theoretical introduction where the practical part is focused o...

  3. Getting the balance right

    International Nuclear Information System (INIS)

    1987-01-01

    This 8 page leaflet is published by the Nuclear Electricity Information Group (NEIG) which is made up of eight different bodies working within the nuclear industry. It aims to present a balanced outline of the facts needed to form an opinion about energy policy in the UK. It looks at the price of electricity, other sources of electricity, (oil and coal, solar power, wind power, water power), safety in the nuclear industry, nuclear waste disposal and risks from radiation. The NEIG is in favour of a balanced energy programme with nuclear energy being only a part of the overall scheme. (U.K.)

  4. In the balance

    DEFF Research Database (Denmark)

    Kluth, Michael Friederich; Pilegaard, Jess

    The present paper seeks to make sense of recent EU naval capability changes by applying neo-realist theory on the EU as an international actor in the global balance of power. The paper compares three different strands of Neo-realist theory by deducting key predictions about the expected defense...... posture of the Union and the expected changes in naval capabilities. The predictions are subsequently held up against recent data on naval military build-up in the EU. The paper argues that the observed patterns are best explained not as bandwagoning with the United States, but as a long-term balancing...

  5. The Impact of Trade Balance in the Current Account of Kosovo’s Balance of Payments

    Directory of Open Access Journals (Sweden)

    Safet Merovci

    2014-02-01

    Full Text Available The trade deficit and specifically the current account deficit are the main challenges that Kosovo‘s economy is facing. According to the Balance of Payments Statistics (BOP, the trade balance of goods is the largest component, expressed in absolute and relative terms and consequently it determines the behavior of the current account balance. Trade deficit to GDP ratio is very high - more than 50 percent. Regarding this, financing the constant deficit of the current account is becoming a real problem, because in the long run it is impossible for a country to spend more than its income without becoming a debtor to the rest of the world. Given the unchanged structure of the current account of the Balance of Payments, we conclude that, an improvement of the trade balance is a precondition to the improvement of the current account balance. This can be done through longterm and sustainable substitution of imports with domestic production and also with effective export promotion. Increasing foreign direct investment and export promotion can be considered, in the longer term, the main way to improve Kosovo's Trade Balance.

  6. MetNet - In situ observational Network and Orbital platform to investigate the Martian environment

    Science.gov (United States)

    Harri, Ari-Matti; Leinonen, Jussi; Merikallio, Sini; Paton, Mark; Haukka, Harri; Polkko, Jouni

    2007-09-01

    MetNet Mars Mission is an in situ observational network and orbital platform mission to investigate the Martian environment and it has been proposed to European Space Agency in response to Call for proposals for the first planning cycle of Cosmic Vision 2015-2025 D/SCI/DJS/SV/val/21851. The MetNet Mars Mission is to be implemented in collaboration with ESA, FMI, LA, IKI and the payload providing science teams. The scope of the MetNet Mission is to deploy 16 MetNet Landers (MNLs) on the Martian surface by using inflatable descent system structures accompanied by an atmospheric sounder and data relay onboard the MetNet Orbiter (MNO), which is based on ESA Mars Express satellite platform. The MNLs are attached on the three sides of the satellite and most of the MNLs are deployed to Mars separately a few weeks prior to the arrival to Mars. The MetNet Orbiter will perform continuous atmospheric soundings thus complementing the accurate in situ observations at the Martian ground produced by the MetNet observation network, as well as the orbiter will serve as the primary data relay between the MetNet Landers and the Earth. The MNLs are equipped with a versatile science payload focused on the atmospheric science of Mars. Detailed characterisation of the Martian atmospheric circulation patterns, boundary layer phenomena, and climatological cycles, as well as interior investigations, require simultaneous in situ meteorological, seismic and magnetic measurements from networks of stations on the Martian surface. MetNet Mars Mission will also provide a crucial support for the safety of large landing missions in general and manned Mars missions in particular. Accurate knowledge of atmospheric conditions and weather data is essential to guarantee safe landings of the forthcoming Mars mission elements.

  7. Water, Ice, and Meteorological Measurements at South Cascade Glacier, Washington, Balance Years 2004 and 2005

    Science.gov (United States)

    Bidlake, William R.; Josberger, Edward G.; Savoca, Mark E.

    2007-01-01

    Winter snow accumulation and summer snow and ice ablation were measured at South Cascade Glacier, Washington, to estimate glacier mass-balance quantities for balance years 2004 and 2005. The North Cascade Range in the vicinity of South Cascade Glacier accumulated smaller than normal winter snowpacks during water years 2004 and 2005. Correspondingly, the balance years 2004 and 2005 maximum winter snow balances of South Cascade Glacier, 2.08 and 1.97 meters water equivalent, respectively, were smaller than the average of such balances since 1959. The 2004 glacier summer balance (-3.73 meters water equivalent) was the eleventh most negative during 1959 to 2005 and the 2005 glacier summer balance (-4.42 meters water equivalent) was the third most negative. The relatively small winter snow balances and unusually negative summer balances of 2004 and 2005 led to an overall loss of glacier mass. The 2004 and 2005 glacier net balances, -1.65 and -2.45 meters water equivalent, respectively, were the seventh and second most negative during 1953 to 2005. For both balance years, the accumulation area ratio was less than 0.05 and the equilibrium line altitude was higher than the glacier. The unusually negative 2004 and 2005 glacier net balances, combined with a negative balance previously reported for 2003, resulted in a cumulative 3-year net balance of -6.20 meters water equivalent. No equal or greater 3-year mass loss has occurred previously during the more than 4 decades of U.S. Geological Survey mass-balance measurements at South Cascade Glacier. Accompanying the glacier mass losses were retreat of the terminus and reduction of total glacier area. The terminus retreated at a rate of about 17 meters per year during balance year 2004 and 15 meters per year during balance year 2005. Glacier area near the end of balance years 2004 and 2005 was 1.82 and 1.75 square kilometers, respectively. Runoff from the basin containing the glacier and from an adjacent nonglacierized basin was

  8. Type 1 Diabetes TrialNet--an international collaborative clinical trials network.

    Science.gov (United States)

    Skyler, Jay S; Greenbaum, Carla J; Lachin, John M; Leschek, Ellen; Rafkin-Mervis, Lisa; Savage, Peter; Spain, Lisa

    2008-12-01

    Type 1 Diabetes TrialNet is an international consortium of clinical research centers aimed at the prevention or delay of type 1 diabetes (T1D). The fundamental goal of TrialNet is to counter the T1D disease process by immune modulation and/or enhancement of beta cell proliferation and regeneration. To achieve this goal, TrialNet researchers are working to better understand the natural history of the disease, to identify persons at risk, and to clinically evaluate novel therapies that balance potential risks and benefits. The particular focus is on studies of preventive measures. In addition, TrialNet evaluates therapies in individuals with newly diagnosed T1D with preserved beta cell function to help determine the risk/benefit profile and gain an initial assessment of potential efficacy in preservation of beta cell function, so that promising agents can be studied in prevention trials. In addition, TrialNet evaluates methodologies that enhance the conduct of its clinical trials, which includes tests of outcome assessment methodology, the evaluation of surrogate markers, and mechanistic studies laying the foundation for future clinical trials.

  9. Inconsistencies in net radiation estimates from use of several models of instruments in a desert environment

    International Nuclear Information System (INIS)

    Kustas, W.P.; Prueger, J.H.; Hipps, L.E.; Hatfield, J.L.; Meek, D.

    1998-01-01

    Studies of surface energy and water balance generally require an accurate estimate of net radiation and its spatial distribution. A project quantifying both short term and seasonal water use of shrub and grass vegetation in the Jornada Experimental Range in New Mexico prompted a study to compare net radiation observations using two types of net radiometers currently being used in research. A set of 12 REBS net radiometers were compared with each other and one Swissteco, over wet and dry surfaces in an arid landscape under clear skies. The set of REBS exhibited significant differences in output over both surfaces. However, they could be cross calibrated to yield values within 10 W m −2 , on average. There was also a significant bias between the REBS and Swissteco over a dry surface, but not over a wet one. The two makes of instrument could be made to agree under the dry conditions by using regression or autoregression techniques. However, the resulting equations would induce bias for the wet surface condition. Thus, it is not possible to cross calibrate these two makes of radiometer over the range of environmental conditions observed. This result indicates that determination of spatial distribution of net radiation over a variable surface should be made with identical instruments which have been cross calibrated. The need still exists for development of a radiometer and calibration procedures which will produce accurate and consistent measurements over a range of surface conditions. (author)

  10. Near-Net Forging Technology Demonstration Program

    Science.gov (United States)

    Hall, I. Keith

    1996-01-01

    Significant advantages in specific mechanical properties, when compared to conventional aluminum (Al) alloys, make aluminum-lithium (Al-Li) alloys attractive candidate materials for use in cryogenic propellant tanks and dry bay structures. However, the cost of Al-Li alloys is typically five times that of 2219 aluminum. If conventional fabrication processes are employed to fabricate launch vehicle structure, the material costs will restrict their utilization. In order to fully exploit the potential cost and performance benefits of Al-Li alloys, it is necessary that near-net manufacturing methods be developed to off-set or reduce raw material costs. Near-net forging is an advanced manufacturing method that uses elevated temperature metal movement (forging) to fabricate a single piece, near-net shape, structure. This process is termed 'near-net' because only a minimal amount of post-forge machining is required. The near-net forging process was developed to reduce the material scrap rate (buy-to-fly ratio) and fabrication costs associated with conventional manufacturing methods. The goal for the near-net forging process, when mature, is to achieve an overall cost reduction of approximately 50 percent compared with conventional manufacturing options for producing structures fabricated from Al-Li alloys. This NASA Marshall Space Flight Center (MSFC) sponsored program has been a part of a unique government / industry partnership, coordinated to develop and demonstrate near-net forging technology. The objective of this program was to demonstrate scale-up of the near-net forging process. This objective was successfully achieved by fabricating four integrally stiffened, 170- inch diameter by 20-inch tall, Al-Li alloy 2195, Y-ring adapters. Initially, two 2195 Al-Li ingots were converted and back extruded to produce four cylindrical blockers. Conventional ring rolling of the blockers was performed to produce ring preforms, which were then contour ring rolled to produce

  11. Ontological Annotation with WordNet

    Energy Technology Data Exchange (ETDEWEB)

    Sanfilippo, Antonio P.; Tratz, Stephen C.; Gregory, Michelle L.; Chappell, Alan R.; Whitney, Paul D.; Posse, Christian; Paulson, Patrick R.; Baddeley, Bob; Hohimer, Ryan E.; White, Amanda M.

    2006-06-06

    Semantic Web applications require robust and accurate annotation tools that are capable of automating the assignment of ontological classes to words in naturally occurring text (ontological annotation). Most current ontologies do not include rich lexical databases and are therefore not easily integrated with word sense disambiguation algorithms that are needed to automate ontological annotation. WordNet provides a potentially ideal solution to this problem as it offers a highly structured lexical conceptual representation that has been extensively used to develop word sense disambiguation algorithms. However, WordNet has not been designed as an ontology, and while it can be easily turned into one, the result of doing this would present users with serious practical limitations due to the great number of concepts (synonym sets) it contains. Moreover, mapping WordNet to an existing ontology may be difficult and requires substantial labor. We propose to overcome these limitations by developing an analytical platform that (1) provides a WordNet-based ontology offering a manageable and yet comprehensive set of concept classes, (2) leverages the lexical richness of WordNet to give an extensive characterization of concept class in terms of lexical instances, and (3) integrates a class recognition algorithm that automates the assignment of concept classes to words in naturally occurring text. The ensuing framework makes available an ontological annotation platform that can be effectively integrated with intelligence analysis systems to facilitate evidence marshaling and sustain the creation and validation of inference models.

  12. Automating Ontological Annotation with WordNet

    Energy Technology Data Exchange (ETDEWEB)

    Sanfilippo, Antonio P.; Tratz, Stephen C.; Gregory, Michelle L.; Chappell, Alan R.; Whitney, Paul D.; Posse, Christian; Paulson, Patrick R.; Baddeley, Bob L.; Hohimer, Ryan E.; White, Amanda M.

    2006-01-22

    Semantic Web applications require robust and accurate annotation tools that are capable of automating the assignment of ontological classes to words in naturally occurring text (ontological annotation). Most current ontologies do not include rich lexical databases and are therefore not easily integrated with word sense disambiguation algorithms that are needed to automate ontological annotation. WordNet provides a potentially ideal solution to this problem as it offers a highly structured lexical conceptual representation that has been extensively used to develop word sense disambiguation algorithms. However, WordNet has not been designed as an ontology, and while it can be easily turned into one, the result of doing this would present users with serious practical limitations due to the great number of concepts (synonym sets) it contains. Moreover, mapping WordNet to an existing ontology may be difficult and requires substantial labor. We propose to overcome these limitations by developing an analytical platform that (1) provides a WordNet-based ontology offering a manageable and yet comprehensive set of concept classes, (2) leverages the lexical richness of WordNet to give an extensive characterization of concept class in terms of lexical instances, and (3) integrates a class recognition algorithm that automates the assignment of concept classes to words in naturally occurring text. The ensuing framework makes available an ontological annotation platform that can be effectively integrated with intelligence analysis systems to facilitate evidence marshaling and sustain the creation and validation of inference models.

  13. Review of FEWS NET Biophysical Monitoring Requirements

    Science.gov (United States)

    Ross, K. W.; Brown, Molly E.; Verdin, J.; Underwood, L. W.

    2009-01-01

    The Famine Early Warning System Network (FEWS NET) provides monitoring and early warning support to decision makers responsible for responding to famine and food insecurity. FEWS NET transforms satellite remote sensing data into rainfall and vegetation information that can be used by these decision makers. The National Aeronautics and Space Administration has recently funded activities to enhance remote sensing inputs to FEWS NET. To elicit Earth observation requirements, a professional review questionnaire was disseminated to FEWS NET expert end-users: it focused upon operational requirements to determine additional useful remote sensing data and; subsequently, beneficial FEWS NET biophysical supplementary inputs. The review was completed by over 40 experts from around the world, enabling a robust set of professional perspectives to be gathered and analyzed rapidly. Reviewers were asked to evaluate the relative importance of environmental variables and spatio-temporal requirements for Earth science data products, in particular for rainfall and vegetation products. The results showed that spatio-temporal resolution requirements are complex and need to vary according to place, time, and hazard: that high resolution remote sensing products continue to be in demand, and that rainfall and vegetation products were valued as data that provide actionable food security information.

  14. The net charge at interfaces between insulators

    International Nuclear Information System (INIS)

    Bristowe, N C; Littlewood, P B; Artacho, Emilio

    2011-01-01

    The issue of the net charge at insulating oxide interfaces is briefly reviewed with the ambition of dispelling myths of such charges being affected by covalency and related charge density effects. For electrostatic analysis purposes, the net charge at such interfaces is defined by the counting of discrete electrons and core ion charges, and by the definition of the reference polarization of the separate, unperturbed bulk materials. The arguments are illustrated for the case of a thin film of LaAlO 3 over SrTiO 3 in the absence of free carriers, for which the net charge is exactly 0.5e per interface formula unit, if the polarization response in both materials is referred to zero bulk values. Further consequences of the argument are extracted for structural and chemical alterations of such interfaces, in which internal rearrangements are distinguished from extrinsic alterations (changes of stoichiometry, redox processes), only the latter affecting the interfacial net charge. The arguments are reviewed alongside the proposal of Stengel and Vanderbilt (2009 Phys. Rev. B 80 241103) of using formal polarization values instead of net interfacial charges, based on the interface theorem of Vanderbilt and King-Smith (1993 Phys. Rev. B 48 4442-55). Implications for non-centrosymmetric materials are discussed, as well as for interfaces for which the charge mismatch is an integer number of polarization quanta. (viewpoint)

  15. Load Balancing in Hypergraphs

    Science.gov (United States)

    Delgosha, Payam; Anantharam, Venkat

    2018-03-01

    Consider a simple locally finite hypergraph on a countable vertex set, where each edge represents one unit of load which should be distributed among the vertices defining the edge. An allocation of load is called balanced if load cannot be moved from a vertex to another that is carrying less load. We analyze the properties of balanced allocations of load. We extend the concept of balancedness from finite hypergraphs to their local weak limits in the sense of Benjamini and Schramm (Electron J Probab 6(23):13, 2001) and Aldous and Steele (in: Probability on discrete structures. Springer, Berlin, pp 1-72, 2004). To do this, we define a notion of unimodularity for hypergraphs which could be considered an extension of unimodularity in graphs. We give a variational formula for the balanced load distribution and, in particular, we characterize it in the special case of unimodular hypergraph Galton-Watson processes. Moreover, we prove the convergence of the maximum load under some conditions. Our work is an extension to hypergraphs of Anantharam and Salez (Ann Appl Probab 26(1):305-327, 2016), which considered load balancing in graphs, and is aimed at more comprehensively resolving conjectures of Hajek (IEEE Trans Inf Theory 36(6):1398-1414, 1990).

  16. Strength and Balance Exercises

    Science.gov (United States)

    ... close to a wall, chair or table for balance. Action: Shift your weight onto one leg. Stand on that foot and stretch the other leg out in front of you, a few inches off the floor. Stand on one leg for eight counts. For an extra workout, flex and point your lifted foot. That is, bend the ankle ...

  17. National energy balance - 1978

    International Nuclear Information System (INIS)

    1978-01-01

    The national energy balance of 1978 shows some modifications in relation to the last year. New tables were included aiming to show the brazilian energy situation, such as the hydraulic potential and the non-renewable energy resources. (E.G.) [pt

  18. Lives in the Balance.

    Science.gov (United States)

    Our Children, 1997

    1997-01-01

    Changes in the workplace that would provide flexibility for working parents are slowly developing and receiving government, business, and societal attention. A sidebar, "Mother, Professional, Volunteer: One Woman's Balancing Act," presents an account of how one woman rearranged her professional life to enable her to do full-time…

  19. Balance of Power

    NARCIS (Netherlands)

    Boone, J.

    2004-01-01

    This paper argues that the efficiency distribution of players in a game determines how aggressively these players interact.We formalize the idea of balance of power: players fight very inefficient players but play softly versus equally (or more) efficient players.This theory of conduct predicts that

  20. National energy balance - 1977

    International Nuclear Information System (INIS)

    1977-01-01

    The national energy balance of the 1976 shows several modifications in relation to the last year. The historical serie is based in more confiable information, from several energy companies. The most greater modifications are on energy source of hard control, such as lignite and charcoal for non-siderurgic uses. (E.G.) [pt

  1. National Energy Balance - 1986

    International Nuclear Information System (INIS)

    Anon.

    1986-01-01

    The National Energy Balance - 1986 shows energy fluxes of several primary and secondary energy sources, since the production to the final consumption in the main economic sectors, since 1970 to 1985. The incorporation of a new brazilian information is done. (E.G.) [pt

  2. Ballet Balance Strategies

    DEFF Research Database (Denmark)

    Pedersen, Camilla; Erleben, Kenny; Sporring, Jon

    2006-01-01

    Animating physically realistic human characters is challenging, since human observers are highly tuned to recognize human cues such as emotion and gender from motion patterns. The main contribution of this paper is a new model firmly based on biomechanics, which is used to animate balance and basic...

  3. Frihed, anerkendelse og balance

    DEFF Research Database (Denmark)

    Anker, Thomas Boysen

    2008-01-01

    Artiklen argumenterer for, at selv ikke den absolut mest familievenlige arbejdsplads vil kunne løse det psykologiske problem med at skabe balance mellem familie og arbejdsliv, fordi ubalancen grundlæggende handler om en anerkendelseskonflikt, som individet ikke altid selv er interesseret i at komme...

  4. Kin Selection - Mutation Balance

    DEFF Research Database (Denmark)

    Dyken, J. David Van; Linksvayer, Timothy Arnold; Wade, Michael J.

    2011-01-01

    selection-mutation balance, which provides an evolutionary null hypothesis for the statics and dynamics of cheating. When social interactions have linear fitness effects and Hamilton´s rule is satisfied, selection is never strong enough to eliminate recurrent cheater mutants from a population, but cheater...

  5. National Energy Balance - 1981

    International Nuclear Information System (INIS)

    Anon.

    1981-01-01

    The National Energy Balance - 1981, shows a new metodology and information in level of several economic sectors, as well as a separation of primary and secondary energy sources, its energy fluxes, i.e. production, imports, exports, consumption, etc...(E.G.) [pt

  6. Balancing Chemical Equations.

    Science.gov (United States)

    Savoy, L. G.

    1988-01-01

    Describes a study of students' ability to balance equations. Answers to a test on this topic were analyzed to determine the level of understanding and processes used by the students. Presented is a method to teach this skill to high school chemistry students. (CW)

  7. Renal aquaporins and water balance disorders

    DEFF Research Database (Denmark)

    Kortenoeven, Marleen; Fenton, Robert A.

    2013-01-01

    BACKGROUND: Aquaporins (AQPs) are a family of proteins that can act as water channels. Regulation of AQPs is critical to osmoregulation and the maintenance of body water homeostasis. Eight AQPs are expressed in the kidney of which five have been shown to play a role in body water balance; AQP1, A......-solute diet and diuretics. GENERAL SIGNIFICANCE: In recent years, our understanding of the underlying mechanisms of water balance disorders has increased enormously, which has opened up several possible new treatment strategies.......BACKGROUND: Aquaporins (AQPs) are a family of proteins that can act as water channels. Regulation of AQPs is critical to osmoregulation and the maintenance of body water homeostasis. Eight AQPs are expressed in the kidney of which five have been shown to play a role in body water balance; AQP1, AQP......2, AQP3, AQP4 and AQP7. AQP2 in particular is regulated by vasopressin. SCOPE OF REVIEW: This review summarizes our current knowledge of the underlying mechanisms of various water balance disorders and their treatment strategies. MAJOR CONCLUSIONS: Dysfunctions of AQPs are involved in disorders...

  8. .net core application lifecycle on Openshift

    CERN Multimedia

    CERN. Geneva

    2017-01-01

    # .net core application lifecycle on Openshift I will show an example of a lifecycle of an OpenShift application with an emphasis on the continuous integration and deployment. The application compatible with [.net Standard](https://docs.microsoft.com/en-us/dotnet/standard/net-standard) can be easily deployed on OpenShift using [Source2Image](https://docs.openshift.com/enterprise/3.0/architecture/core_concepts/builds_and_image_streams.html#source-build) functionality, which doesn't require developers to maintain docker images of the application. I will also present how to efficiently integrate this feature into GitLab pipelines with an automated deployment of the "review" environment, as one its parts.

  9. Towards Self-Managed Executable Petri Nets

    DEFF Research Database (Denmark)

    Hansen, Klaus Marius; Zhang, Weishan; Ingstrup, Mads

    2008-01-01

    An issue in self-managed systems is that different abstractions and programming models are used on different architectural layers, leading to systems that are harder to build and understand. To alleviate this, we introduce a self-management approach which combines high-level Petri nets...... with the capability of distributed communication among nets. Organized in a three-layer goal management, change management, and component control architecture this allows for self-management in distributed systems. We validate the approach through the Flamenco/CPN middleware that allows for self-management of service......-oriented pervasive computing systems through the runtime interpretation of colored Petri nets. The current work focuses on the change management and component control layers....

  10. Implementation of CLP4NET in Bulgaria

    International Nuclear Information System (INIS)

    Naydenova, I.; Pironkov, L.; Filipov, A.; Petrova, T.; Tsochev, G.; Ganev, I.

    2016-01-01

    Full text: Networking solutions (networks of excellence, communities of practice, knowledge portals, etc.) are recognized as effective tools for nuclear training and education services, transfer of good practices, knowledge and programmes, and knowledge management. In addition, the e-learning is recommended as a state of the art and cost effective approach for supplementing the traditional face to face training and education programmes. Thus, the Cyber Learning Platform for Nuclear Education and Training (CLP4NET) was implemented into the Kozloduy Nuclear Power Plant (KNPP) Training System. Based on the experience of KNPP, the CLP4NET was implemented also at the College of Energy and Electronics (CEE), Technical University of Sofia (TU-Sofia), providing an appropriate tool for further establishment of a National Nuclear Network of Competency. The current study is focused mainly on specific issues and lessons learned during the installation of CLP4NET at the CEE, TU-Sofia. (author

  11. Model-Based Requirements Analysis for Reactive Systems with UML Sequence Diagrams and Coloured Petri Nets

    DEFF Research Database (Denmark)

    Tjell, Simon; Lassen, Kristian Bisgaard

    2008-01-01

    In this paper, we describe a formal foundation for a specialized approach to automatically checking traces against real-time requirements. The traces are obtained from simulation of Coloured Petri Net (CPN) models of reactive systems. The real-time requirements are expressed in terms of a derivat...

  12. Statistical inference for remote sensing-based estimates of net deforestation

    Science.gov (United States)

    Ronald E. McRoberts; Brian F. Walters

    2012-01-01

    Statistical inference requires expression of an estimate in probabilistic terms, usually in the form of a confidence interval. An approach to constructing confidence intervals for remote sensing-based estimates of net deforestation is illustrated. The approach is based on post-classification methods using two independent forest/non-forest classifications because...

  13. Predicted net efflux of radiocarbon from the ocean and increase in atmospheric radiocarbon content

    Science.gov (United States)

    Caldeira, Ken; Rau, Greg H.; Duffy, Philip B.

    Prior to changes introduced by man, production of radiocarbon (14C) in the stratosphere nearly balanced the flux of 14C from the atmosphere to the ocean and land biosphere, which in turn nearly balanced radioactive decay in these 14C reservoirs. This balance has been altered by land-use changes, fossil-fuel burning, and atmospheric nuclear detonations. Here, we use a model of the global carbon cycle to quantify these radiocarbon fluxes and make predictions about their magnitude in the future. Atmospheric nuclear detonations increased atmospheric 14C content by about 80% by the mid-1960's. Since that time, the 14C content of the atmosphere has been diminishing as this bomb radiocarbon has been entering the oceans and terrestrial biosphere. However, we predict that atmospheric 14C content will reach a minimum and start to increase within the next few years if fossil-fuel burning continues according to a “business-as-usual” scenario, even though fossil fuels are devoid of 14C. This will happen because fossil-fuel carbon diminishes the net flux of 14C from the atmosphere to the oceans and land biosphere, forcing 14C to accumulate in the atmosphere. Furthermore, the net flux of both bomb and natural 14C into the ocean are predicted to continue to slow and then, in the middle of the next century, to reverse, so that there will be a net flux of 14C from the ocean to the atmosphere. The predicted reversal of net 14C fluxes into the ocean is a further example of human impacts on the global carbon cycle.

  14. Deep Belief Nets for Topic Modeling

    DEFF Research Database (Denmark)

    Maaløe, Lars; Arngren, Morten; Winther, Ole

    2015-01-01

    -formative. In this paper we describe large-scale content based collaborative filtering for digital publishing. To solve the digital publishing recommender problem we compare two approaches: latent Dirichlet allocation (LDA) and deep be-lief nets (DBN) that both find low-dimensional latent representations for documents....... Efficient retrieval can be carried out in the latent representation. We work both on public benchmarks and digital media content provided by Issuu, an on-line publishing platform. This article also comes with a newly developed deep belief nets toolbox for topic modeling tailored towards performance...

  15. State Space Methods for Timed Petri Nets

    DEFF Research Database (Denmark)

    Christensen, Søren; Jensen, Kurt; Mailund, Thomas

    2001-01-01

    it possible to condense the usually infinite state space of a timed Petri net into a finite condensed state space without loosing analysis power. The second method supports on-the-fly verification of certain safety properties of timed systems. We discuss the application of the two methods in a number......We present two recently developed state space methods for timed Petri nets. The two methods reconciles state space methods and time concepts based on the introduction of a global clock and associating time stamps to tokens. The first method is based on an equivalence relation on states which makes...

  16. A Lightweight TwiddleNet Portal

    Science.gov (United States)

    2008-03-01

    dimensions of 2.8 x 0.7 x 4.6 inches make for a very good tool for TwiddleNet missions. Its Lithium -ion battery with 1200 mAh energy gives approximately...Wireless Connectivity IrDA, Bluetooth, IEEE 802.11b Battery Lithium ion Approximate Dimensions (in) 2.8 x 0.7 x 4.6 Weight (oz) 6.2 ROM 128 MB...designed to exploit the multiple networking modalities available in the current generation of smartphones . TwiddleNet enables well-organized and well

  17. Introducing NET 40 With Visual Studio 2010

    CERN Document Server

    Mackey, A

    2010-01-01

    Microsoft is introducing a large number of changes to the way that the .NET Framework operates. Familiar technologies are being altered, best practices replaced, and developer methodologies adjusted. Many developers find it hard to keep up with the pace of change across .NET's ever-widening array of technologies. You may know what's happening in C#, but how about the Azure cloud? How is that going to affect your work? What are the limitations of the new pLINQ syntax? What you need is a roadmap. A guide to help you see the innovations that matter and to give you a head start on the opportunitie

  18. The Schmehausen cable net cooling tower

    International Nuclear Information System (INIS)

    Schlaich, J.; Mayr, G.; Weber, P.; Jasch, E.

    1976-01-01

    The prototype of a large cable net shell as a natural-draught cooling tower for the THTR-300 is presented. Results of wind tunnel tests and calculations are given, and the capacity is discussed. Design features of the main components are presented in illustrations and are described with regard to the construction process of the cooling tower. Finally, it is shown that the cable net cooling tower is a suitable construction for large dimensions and caving-in or seismic areas. (orig./HP) [de

  19. Pro ASP.NET 4 CMS

    CERN Document Server

    Harris, Alan

    2010-01-01

    To be a successful ASP.NET 4 developer, you need to know how to apply the vast array of new functionality available in the latest release of the .NET 4 Framework and Visual Studio 2010. This book will immerse you in a variety of advanced topics, including architecting different application data tiers, memory caching paradigms, data mining, and search engine optimization. Working through step-by-step exercises using P/LINQ, DLR, MEF, MVC, IronPython, Axum, and Ajax, you will learn a variety of approaches to building each of the key application tiers common to all web solutions. Using a proven t

  20. Net shape powder processing of aluminium

    International Nuclear Information System (INIS)

    Schaffer, G.B.

    2000-01-01

    The increasing interest in light weight materials coupled to the need for cost-effective processing have combined to create a significant opportunity for aluminium powder metallurgy. Net shape processing of aluminium using the classical press-and-sinter powder metallurgy technique is a unique and important metal-forming method which is cost effective in producing complex parts at, or very close to, final dimensions. This paper provides an overview of the net shape powder processing of aluminium. Current research is critically reviewed and the future potential is briefly considered