WorldWideScience

Sample records for nephro-blastomas information dedicated

  1. Understanding nephro-blastomas. Information dedicated to parents and relatives

    International Nuclear Information System (INIS)

    Brusco, S.; Carretier, J.; Delavigne, V.; Fervers, B.; Leichtnam-Dugarin, L.; Bergeron, C.; Claude, L.; Philip, T.; Boccon-Gibod, L.; Coze, C.; Leclair, M.D.

    2006-01-01

    In response to the evolution of the information-seeking behaviour of patients and concerns from health professionals regarding cancer patient information, the French National Federation of Comprehensive Cancer Centres (FNCLCC) introduced, in 1998, an information and education program dedicated to patients and relatives, the SOR SAVOIR PATIENT program. The methodology of this program adheres to established quality criteria regarding the elaboration of patient information. Cancer patient information developed in this program is based on clinical practice guidelines produced by the FNCLCC and the twenty French regional cancer centres, the National League against Cancer, The National Cancer Institute, the French Hospital Federation, the National Oncology Federation of Regional and University Hospitals, the French Oncology Federation of General Hospitals, many learned societies, as well as an active participation of patients, former patients and care-givers. The handbook SOR SAVOIR PATIENT Understanding nephro-blastomas is an adapted version of various scientific publications and international clinical practice guidelines, validated by oncology experts and by the Nephro-blastomas Committee of the French Society against Cancers and Leukemias in children and adolescents (SFCE). It was elaborated with the active participation of parents and other family members. It is meant to provide a basis for the explanation of the disease, to help parents asking questions, and to facilitate discussions with the health-care team. It is available from the FNCLCC (101, rue de Tolbiac, 75013 PARIS, Tel. (0033)1 76 64 78 00, www.fncicc.fr). This document was validated at the end of 2005 and published in May 2006. SOR SAVOIR PATIENT guides are systematically updated when new research becomes available. Information leaflets, extracted from the handbook SOR SAVOIR PATIENT Understanding nephro-blastomas and published in this edition of the Cancer et Radiotherapie, describe the physiopathology

  2. One century of advancement in knowledge and treatment of nephro-blastomas

    International Nuclear Information System (INIS)

    Habraud, J.L.; Pein, F.; Moncho, V.

    2000-01-01

    Since its initial description by Max Wilms over a century ago, nephro-blastomas has benefited from considerable improvements both in terms of basic knowledge about it and management of it. Today, the majority of these very young patients can expect a long-term survival in excess of 90% at the price of a light therapy that combines surgical resection, chemotherapy based on ill-toxic agents, and in selected cases, radiotherapy of remarkably low toxicity. The contribution of large international studies will be emphasized here. (authors)

  3. Management of the nephro-blastoma ( about 42 cases). Experience of the oncology radiotherapy service of the Benbadis university hospital center of Constantine

    International Nuclear Information System (INIS)

    Touhem, S.; Abbane, M.; Salah Bali, M.; Djemaa, A.

    2009-01-01

    The favorable forms of nephro-blastoma of stage 1 or 2 represent 80% of cases and cure in more than 90% of cases. The current objective is to improve the quality of life of patients by reducing the treatment sequelae (growth disorders) and to limit the postoperative chemotherapy and radiotherapy to the unfavorable forms. (N.C.)

  4. Dedication

    OpenAIRE

    2013-01-01

    This work is dedicated, to my mom, Bridget, and my dad, (the late) Daniel Enwerem, who taught me to respect people but not fear them; and to those who are engaged or have been victims in the struggle for an egalitarian society in Nigeria.

  5. [Information quality in general public French-speaking websites dedicated to oral cancer detection].

    Science.gov (United States)

    Vivien, A; Kowalski, V; Chatellier, A; Babin, E; Bénateau, H; Veyssière, A

    2017-02-01

    The goal set by the French highest national authorities in the 2014-2019 Cancer Plan is to "heal more sick persons by promoting early diagnosis through screening". Screening requires information. Nowadays, Internet allows for access to information "in one click". The aim of our study was to evaluate the quality of information found on the Internet. Several sites dedicated to oral cavity cancer screening were selected on Google. The quality of health information found in these sites was evaluated by the DISCERN questionnaire. The quality of decision support provided by the sites was evaluated by the IPDAS checklist. Twenty-seven sites were selected. The average DISCERN score was 25.1/75 (15/75 to 40/75). Eighteen sites (66.6%) had very poor, 8 sites (29.6%) had poor and 1 site had average information quality. IPDAS scores ranged from 11.1 to 38.1. Eight sites (29.6%) had less than 20%, 14 sites (51.9%) had between 20 and 30% and 5 sites (18.5%) had 30% or more validated criteria. No site achieved the pass mark. The quality of general public French-speaking website dedicated to oral cancer detection is very bad. The role of health professionals such as general practitioners and head and neck surgeons, remains essential. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  6. Hobby-related information-seeking behaviour of highly dedicated online museum visitors

    DEFF Research Database (Denmark)

    Skov, Mette

    2013-01-01

    collectors and liberal arts enthusiasts. Analysis showed that the two hobby classes have distinct profiles including differences in the nature of their knowledge acquisition. Results. Across the two hobby classes, participants can be characterised as special interest museum visitors pursuing a long......-standing interest or hobby. The identified information needs were surprisingly well-defined known item needs and only few exploratory information needs were identified. Participants stressed the importance of personal channels and the social context of the hobby. Conclusions. The present study contributes...

  7. Database dedicated to information published during the Benelux conferences on hormone and veterinary drug residue analyses

    NARCIS (Netherlands)

    Impens, S.; Brabander, H.F. de; Bergwerff, A.A.; Ginkel, L.A. van; Schilt, R.; Stephany, R.W.; Wasch, K. de; Courtheyn, D.; Peteghem, C. van

    2002-01-01

    Every other year scientists working in the field of residue analysis participate the "International Symposium on Hormone and Veterinary Drug Residue Analysis" and "Euroresidue" conferences. In each symposium a lot of innovative information is presented. In order to obtain a retrieval system for this

  8. Financial Ratio Analysis: the Development of a Dedicated Management Information System

    Directory of Open Access Journals (Sweden)

    Voicu-Dan Dragomir

    2007-01-01

    Full Text Available This paper disseminates the results of the development process for a financial analysis information system. The system has been subject to conceptual design using the Unified Modeling Language (UML and has been implemented in object-oriented manner using the Visual Basic .NET 2003 programming language. The classic financial analysis literature is focused on the chain-substitution method of computing the prior-year to current-year variation of linked financial ratios. We have applied this technique on the DuPont System of analysis concerning the Return on Equity ratio, by designing several structural UML diagrams depicting the breakdown and analysis of each financial ratio involved. The resulting computer application offers a flexible approach to the analytical tools: the user is required to introduce the raw data and the system provides both table-style and charted information on the output of computation. User-friendliness is also a key feature of this particular financial analysis application.

  9. Dedicated memory structure holding data for detecting available worker thread(s) and informing available worker thread(s) of task(s) to execute

    Energy Technology Data Exchange (ETDEWEB)

    Chiu, George L.; Eichenberger, Alexandre E.; O' Brien, John K. P.

    2016-12-13

    The present disclosure relates generally to a dedicated memory structure (that is, hardware device) holding data for detecting available worker thread(s) and informing available worker thread(s) of task(s) to execute.

  10. An XML schema for automated data integration in a Multi-Source Information System dedicated to end-stage renal disease.

    Science.gov (United States)

    Dufour, Eric; Ben Saïd, Mohamed; Jais, Jean Philippe; Le Mignot, Loic; Richard, Jean-Baptiste; Landais, Paul

    2009-01-01

    Data exchange and interoperability between clinical information systems represent a crucial issue in the context of patient record data collection. An XML representation schema adapted to end-stage renal disease (ESRD) patients was developed and successfully tested against patient data in the dedicated Multi-Source Information System (MSIS) active file (more than 16,000 patient records). The ESRD-XML-Schema is organized into Schema subsets respecting the coherence of the clinical information and enriched with coherent data types. Tests are realized against XML-data files generated in conformity with the ESRD-XML Schema. Manual tests allowed the XML schema validation of the data format and content. Programmatic tests allowed the design of generic XML parsing routines, a portable object data model representation and the implementation of automatic data-exchange flows with the MSIS database system. The ESRD-XML-Schema represents a valid framework for data exchange and supports interoperability. Its modular design offers opportunity to simplify physicians' multiple tasks in order to privilege their clinical work.

  11. Musculoskeletal MRI: dedicated systems

    International Nuclear Information System (INIS)

    Masciocchi, C.; Barile, A.; Satragno, L.

    2000-01-01

    The ''dedicated'' MRI units have characteristics of high diagnostic accuracy and lower installation and management costs as compared with whole-body systems. The dedicated MRI units are easy to install. The low weight allows their installation also under unfavorable circumstances. In a dedicated system cost-effectiveness and ease of installation must be accompanied by the capability of providing high-quality images. In our experience, the high number of examinations performed, the most part of which provided with the surgical controls, allowed an accurate evaluation of the diagnostic potentialities of the dedicated magnet. We were not able to perform the examinations in only 3 % of cases due to the physical shape of the patient and the clinical condition of the patient which may hinder the correct positioning of the limb. The overlapping of the diagnostic accuracy of the E-scan and Artoscan units in the study of the lower limbs, compared with whole-body units and surgery, prompted us to exploit the potentialities of the E-Scan in the study of the shoulder. We had a good correlation between E-Scan, whole-body units, and surgical findings, which confirmed the high diagnostic accuracy of the dedicated system. In conclusion, in our experience carried out in the musculoskeletal system, the dedicated magnets showed promising results. Their diagnostic reliability and utility was comparable to that obtained from conventional units operating at higher magnetic fields. (orig.)

  12. Dedicated bifurcation stents

    Directory of Open Access Journals (Sweden)

    Ajith Ananthakrishna Pillai

    2012-03-01

    Full Text Available Bifurcation percutaneous coronary intervention (PCI is still a difficult call for the interventionist despite advancements in the instrumentation, technical skill and the imaging modalities. With major cardiac events relate to the side-branch (SB compromise, the concept and practice of dedicated bifurcation stents seems exciting. Several designs of such dedicated stents are currently undergoing trials. This novel concept and pristine technology offers new hope notwithstanding the fact that we need to go a long way in widespread acceptance and practice of these gadgets. Some of these designs even though looks enterprising, the mere complex delivering technique and the demanding knowledge of the exact coronary anatomy makes their routine use challenging.

  13. Dedicating Fermilab's Collider

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1986-01-15

    It was a bold move to have a fullscale dedication ceremony for the new proton-antiproton Collider at the Fermilab Tevatron on 13 October, two days before the first collisions were seen. However the particles dutifully behaved as required, and over the following weekend the Collider delivered its goods at a total energy of 1600 GeV, significantly boosting the world record for laboratory collisions.

  14. Editors note, and Dedication

    Directory of Open Access Journals (Sweden)

    Laura Mugnai

    2011-12-01

    Full Text Available This Supplement to volume 50 of Phytopathologia Mediterranea contains original, peer reviewed research papers, prepared from presentations at the 7th International Workshop on Grapevine Trunk Diseases (IWGTD. This Workshop was held in Santa Cruz, Chile, 17–21 January 2010, and was organized by the International Council on Grapevine Trunk Diseases (ICGTD.  Publication of this Supplement has been financially assisted by the International Society for Plant Pathology (ISPP.This Supplementary Issue of Phytopathologia Mediterranea is dedicated to the memory of Dr Luigi Chiarappa, the founder and inspiration of the ICGTD.  

  15. Dedicated accelerator and microprobe line

    International Nuclear Information System (INIS)

    Malmqvist, K.G.; Hylten, G.; Hult, M.; Haakansson, K.; Knox, J.M.; Larsson, N.P.O.; Nilsson, C.; Pallon, J.; Schofield, R.; Swietlicki, E.; Tapper, U.A.S.; Yang Changyi

    1993-01-01

    The development of a dedicated facility for nuclear microprobe analysis and the experiences from using it are discussed. The general properties of the present Lund nuclear microprobe will be described and the advantages of using a dedicated accelerator discussed. (orig.)

  16. Progress on dedicated animal PET

    International Nuclear Information System (INIS)

    Liu Wei

    2002-01-01

    Positron emission tomography, as the leading technology providing molecular imaging of biological processes, is widely used on living laboratory animals. High-resolution dedicated animal PET scanners have been developed. Although the dedicated animal PET faces obstacles and challenges, this advanced technology would play an important role in molecular biomedicine researches, such as diseases study, medicine development, and gene therapy

  17. Analysis of the Organ Offers Received From European Union Countries Before and After the Introduction of a Dedicated Information Technology Portal: The COORENOR/FOEDUS Portal.

    Science.gov (United States)

    Peritore, D; Rizzato, L; Di Ciaccio, P; Trapani, S; Carella, C; Oliveti, A; Rizzo, A; Nanni Costa, A

    2017-05-01

    To optimize the use of nontransplantable organs in their own territory, the European Commission, as part of a project led by Italy, has promoted the use of an information technology (IT) portal, the COORENOR portal, developed by the Czech Republic in 2012, which evolved to become FOEDUS in 2015. To evaluate the impact of the portal on our reality, we analyzed the number and type of offers received and organs imported in the previous 48 months (period A) as well as the 48 months after the introduction of the portal (period B). We also examined the origin and the offer mode. The offers received were 404 and 753, respectively, in the two periods, with 315 (41.8%) organs received through the portal. The organs transplanted were 53 and 64, respectively, in the two periods; 20 (31.2%) were sent through the portal. The most commonly offered organs are lungs (36.7% and 29.3% of offers in periods A and B, respectively). The most transplanted organ is the liver (59.4% and 45% of transplants in periods A and B, respectively). The use of the portal has gradually increased, growing from 16.4% of the offer mode in 2012 to 84.7% in 2016. The increase of offers related to the increase of donations and the attitude to the sharing of resources has determined an increase of 19.2% of total transplants, especially for certain types such as pediatric transplants. The portal, ensuring speed and simultaneity of offer, real time sharing of information and transparency of allocation, is also used for trade in the International Partnership Agreements. Therefore, transplants have been conditioned by the existing agreements with Greece, Malta, and the countries of the South Transplant Alliance. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. Dedication

    NARCIS (Netherlands)

    Hoek, van den C.

    1967-01-01

    Joséphine Th. Koster entered her service at the Rijksherbarium as an assistant, April 1930, in the midst of the economic crisis. She was engaged as an, unsalaried collaborator, the then current type of position the Netherlands’ State could offer its scientific offspring. When Prof. Dr. H. J. Lam,

  19. Dedication

    NARCIS (Netherlands)

    NN,

    1948-01-01

    It is not without some pride and much satisfaction that the present volume, fourth planned in the series, second in sequence of publication, is brought to a successful end. Satisfaction I feel through the fact that the scheme and aim of this work is not only understood by the scientific-botanical

  20. Dedication

    NARCIS (Netherlands)

    Holttum, R.E.

    1959-01-01

    CARL FREDRICK ALBERT CHRISTENSEN (1872-1942) was the founder of modern fern taxonomy. To appreciate the scope of his work, it is necessary to understand the confusions of thought on the subject which persisted through the 19th century and were still evident in the summary prepared (by DIELS) for

  1. Perceived Convenience, Compatibility, and Media Richness Contribute Significantly toDedicated E-book Reader Acceptance. A Review of: Lai, J.-Y., & Chang, C.-Y. (2011. User attitudes toward dedicated e-book readers for reading: The effects of convenience, compatibility and media richness. Online Information Review, 35(4, 558-580.

    Directory of Open Access Journals (Sweden)

    Theresa S. Arndt

    2012-06-01

    Full Text Available Objective – Investigates the effects ofperceived convenience, compatibility andmedia richness on users’ attitudes towarddedicated e-book readers.Design – Convenience sample survey.Setting – Taiwanese university.Subjects – A total of 288 students at the seniorsecondary (5%, four-year university (78%,and graduate student (17% levels. Malefemaleparticipation was approximately equal.Methods – Students completed a 23-itemsurvey on dedicated e-book readers, withquestions on perceived usefulness, perceivedease of use, intention to use, convenience,compatibility, and media richness. Data wasanalyzed using the partial least squaresstatistical technique.Main Results – Users state an increasedintention to use dedicated e-book readers ifthey perceive the technology to be compatiblewith what they desire in a “book,” if the devicedelivers rich media content, and if the device isconvenient. Compatibility was found tosignificantly affect perceived ease of use, andwas found to be the strongest influence onintent to use a dedicated e-book reader.Compatibility, media richness andconvenience also increased the perceivedusefulness of dedicated e-book readers.Conclusion – Users will prefer dedicated e-book readers that are compatible with their preferences in a “book,” that deliver media-rich content, and that they find convenient. The study has implications for the design and development of e-book reading devices.

  2. Dedicated radial ventriculography pigtail catheter

    Energy Technology Data Exchange (ETDEWEB)

    Vidovich, Mladen I., E-mail: miv@uic.edu

    2013-05-15

    A new dedicated cardiac ventriculography catheter was specifically designed for radial and upper arm arterial access approach. Two catheter configurations have been developed to facilitate retrograde crossing of the aortic valve and to conform to various subclavian, ascending aortic and left ventricular anatomies. The “short” dedicated radial ventriculography catheter is suited for horizontal ascending aortas, obese body habitus, short stature and small ventricular cavities. The “long” dedicated radial ventriculography catheter is suited for vertical ascending aortas, thin body habitus, tall stature and larger ventricular cavities. This new design allows for improved performance, faster and simpler insertion in the left ventricle which can reduce procedure time, radiation exposure and propensity for radial artery spasm due to excessive catheter manipulation. Two different catheter configurations allow for optimal catheter selection in a broad range of patient anatomies. The catheter is exceptionally stable during contrast power injection and provides equivalent cavity opacification to traditional femoral ventriculography catheter designs.

  3. Scalable cloud without dedicated storage

    Science.gov (United States)

    Batkovich, D. V.; Kompaniets, M. V.; Zarochentsev, A. K.

    2015-05-01

    We present a prototype of a scalable computing cloud. It is intended to be deployed on the basis of a cluster without the separate dedicated storage. The dedicated storage is replaced by the distributed software storage. In addition, all cluster nodes are used both as computing nodes and as storage nodes. This solution increases utilization of the cluster resources as well as improves fault tolerance and performance of the distributed storage. Another advantage of this solution is high scalability with a relatively low initial and maintenance cost. The solution is built on the basis of the open source components like OpenStack, CEPH, etc.

  4. The AMFEC: a tool for dedications

    International Nuclear Information System (INIS)

    Pastor Escobar, H.; Gomar Vidal, J.

    2014-01-01

    The process of dedication, consists of a series of activities intended to ensure that a component of commercial grade can be used in applications related with the Security at nuclear facilities. However, in one of the steps of essential dedication, is often the problem defined with certain accuracy the most relevant characteristics or critical acceptance of the component characteristics, which through its verification, give by valid the commercial component for security-related use. Due to lack of information, they can sometimes not be identified clearly, and therefore it is necessary to resort to some alternative method that will allow us to define them, the AMFEC (analysis of failure modes, effects and criticality. (Author)

  5. Dedicated Filter for Robust Occupancy Grid Mapping

    Directory of Open Access Journals (Sweden)

    KS Nagla

    2015-03-01

    Full Text Available Sensor based perception of the environment is an emerging area of the mobile robot research where sensors play a pivotal role. For autonomous mobile robots, the fundamental requirement is the convergent of the range information in to high level internal representation. Internal representation in the form of occupancy grid is commonly used in autonomous mobile robots due to its various advantages. There are several sensors such as vision sensor, laser rage finder, and ultrasonic and infrared sensors etc. play roles in mapping. However the sensor information failure, sensor inaccuracies, noise, and slow response are the major causes of an error in the mapping. To improve the reliability of the mobile robot mapping multisensory data fusion is considered as an optimal solution. This paper presents a novel architecture of sensor fusion frame work in which a dedicated filter (DF is proposed to increase the robustness of the occupancy grid for indoor environment. The technique has been experimentally verified for different indoor test environments. The proposed configuration shows improvement in the occupancy grid with the implementation of dedicated filters.

  6. Dedicated education unit: student perspectives.

    Science.gov (United States)

    Nishioka, Vicki M; Coe, Michael T; Hanita, Makoto; Moscato, Susan R

    2014-01-01

    The study compared students' perceptions of their clinical learning experiences in a dedicated education unit (DEU) with their experiences in traditional clinical education. Unlike traditional academic-instructor models, expert nurses in the DEU provide clinical education to students with faculty support. This repeated measures design used student surveys, supplemented by focus group data. Students were more likely to agree that their clinical learning experience was high quality and they had a consistent mentoring relationship during DEU rotations. Students also reported the quality of the unit's learning environment, the leadership style of the nurse manager, and the nursing care on the unit was more favorable in DEUs than traditional units. Consistent with their changed role in DEUs, faculty members were less active in helping students integrate theory and practice. These findings provide additional evidence of the value that the DEU model contributes to high-quality clinical education.

  7. [Advanced online search techniques and dedicated search engines for physicians].

    Science.gov (United States)

    Nahum, Yoav

    2008-02-01

    In recent years search engines have become an essential tool in the work of physicians. This article will review advanced search techniques from the world of information specialists, as well as some advanced search engine operators that may help physicians improve their online search capabilities, and maximize the yield of their searches. This article also reviews popular dedicated scientific and biomedical literature search engines.

  8. Cost effective nuclear commercial grade dedication

    International Nuclear Information System (INIS)

    Maletz, J.J.; Marston, M.J.

    1991-01-01

    This paper describes a new computerized database method to create/edit/view specification technical data sheets (mini-specifications) for procurement of spare parts for nuclear facility maintenance and to develop information that could support possible future facility life extension efforts. This method may reduce cost when compared with current manual methods. The use of standardized technical data sheets (mini-specifications) for items of the same category improves efficiency. This method can be used for a variety of tasks, including: Nuclear safety-related procurement; Non-safety related procurement; Commercial grade item procurement/dedication; Evaluation of replacement items. This program will assist the nuclear facility in upgrading its procurement activities consistent with the recent NUMARC Procurement Initiative. Proper utilization of the program will assist the user in assuring that the procured items are correct for the applications, provide data to assist in detecting fraudulent materials, minimize human error in withdrawing database information, improve data retrievability, improve traceability, and reduce long-term procurement costs

  9. Classification of cognitive systems dedicated to data sharing

    Science.gov (United States)

    Ogiela, Lidia; Ogiela, Marek R.

    2017-08-01

    In this paper will be presented classification of new cognitive information systems dedicated to cryptographic data splitting and sharing processes. Cognitive processes of semantic data analysis and interpretation, will be used to describe new classes of intelligent information and vision systems. In addition, cryptographic data splitting algorithms and cryptographic threshold schemes will be used to improve processes of secure and efficient information management with application of such cognitive systems. The utility of the proposed cognitive sharing procedures and distributed data sharing algorithms will be also presented. A few possible application of cognitive approaches for visual information management and encryption will be also described.

  10. DARE: a dedicated aerosols retrieval instrument

    NARCIS (Netherlands)

    Court, A.J.; Smorenburg, K.; Courrèges-Lacoste, G.B.; Visser, H.; Leeuw, G. de; Decae, R.

    2004-01-01

    Satellite remote sensing of aerosols is a largely unresolved problem. A dedicated instrument aimed at aerosols would be able to reduce the large uncertainties connected to this kind of remote sensing. TNO is performing a study of a space based instrument for aerosol measurements, together with the

  11. PRIMARY RENAL MASSES IN CHILDREN IN CAMEROON: A PLEA ...

    African Journals Online (AJOL)

    Fifteen of 21 patients (71.4%) with nephro-blastoma survived past 5 years. Conclusion While nephroblastoma is the most common tumor cell type, lymphomas and adenocarcinomas occur in over 20% of children with renal tumors. Therefore, prior to chemotherapy and radiotherapy, it is imperative to make a histologic ...

  12. Dedication of Fermilab's LHC Remote Operations Center

    CERN Multimedia

    Claudia Marcelloni

    2007-01-01

    Fermilab's Remote Operations Center will be dedicated simultaneously at Fermilab in the U.S. and from CMS (Point 5) in Cessy, France. Speakers will include: from the U.S. DOE Undersecretary for Science Raymond Orbach and Fermilab Director Pier Oddone (U.S.); and from CERN Director General Robert Aymar, CMS Spokesperson Jim Virdee, LHC Project Leader Lyn Evans and US CMS Project Manager Joel Butler.

  13. Dedicating Fermilab's Collider

    International Nuclear Information System (INIS)

    Anon.

    1986-01-01

    It was a bold move to have a fullscale dedication ceremony for the new proton-antiproton Collider at the Fermilab Tevatron on 13 October, two days before the first collisions were seen. However the particles dutifully behaved as required, and over the following weekend the Collider delivered its goods at a total energy of 1600 GeV, significantly boosting the world record for laboratory collisions

  14. Clear-PEM, a dedicated PET camera for mammography

    CERN Document Server

    Lecoq, P

    2002-01-01

    Preliminary results suggest that Positron Emission Mammography (PEM) can offer a noninvasive method for the diagnosis of breast cancer. Metabolic images from PEM contain unique information not available from conventional morphologic imaging techniques and aid in expeditiously establishing the diagnosis of cancer. A dedicated machine seems to offer better perspectives in terms of position resolution and sensitivity. This paper describes the concept of Clear-PEM, the system presently developed by the Crystal Clear Collaboration at CERN for an evaluation of this approach. This device is based on new crystals introduced by the Crystal Clear as well as on modern data acquisition techniques developed for the large experiments in high energy physics experiments.

  15. A PET imaging system dedicated to mammography

    CERN Document Server

    Varela, J

    2007-01-01

    The imaging system Clear-PEM for positron emission mammography, under development within the framework of the Crystal Clear Collaboration at CERN, is presented. The detector is based on pixelized LYSO crystals optically coupled to avalanche photodiodes (APD) and readout by a fast low-noise electronic system. A dedicated digital trigger and data acquisition system is used for on-line selection of coincidence events with high efficiency, large bandwidth and negligible dead-time. The detector module performance was characterized in detail.

  16. Ford F250 Dedicated CNG Pickup

    International Nuclear Information System (INIS)

    Eudy, Leslie

    1999-01-01

    The U.S. Department of Energy (DOE) is encouraging the use of alternative fuels and alternative fuel vehicles (AFVs). To support this activity, DOE has directed the National Renewable Energy Laboratory (NREL) to conduct projects to evaluate the performance and acceptability of light-duty AFVs. In this study, we tested a pair of 1998 Ford F-250 pickups: one dedicated compressed natural gas (CNG) model and a gasoline model as closely matched as possible. Each vehicle was run through a series of tests to evaluate acceleration, fuel economy, braking, and cold-start capabilities, as well as more subjective performance indicators such as handling, climate control, and noise

  17. Dedicated low-field MRI in mice

    International Nuclear Information System (INIS)

    Choquet, P; Breton, E; Goetz, C; Constantinesco, A; Marin, C

    2009-01-01

    The rationale of this work is to point out the relevance of in vivo MR images of mice obtained using a dedicated low-field system. For this purpose a small 0.1 T water-cooled electro-magnet and solenoidal radio frequency (RF) transmit-receive coils were used. All MR images were acquired in three-dimensional (3D) mode. An isolation cell was designed allowing easy placement of the RF coils and simple delivery of gaseous anesthesia as well as warming of the animal. Images with and without contrast agent were obtained in total acquisition times on the order of half an hour to four hours on normal mice as well as on animals bearing tumors. Typical in plane pixel dimensions range from 200 x 200 to 500 x 500 μm 2 with slice thicknesses ranging between 0.65 and 1.50 mm. This work shows that, besides light installation and low cost, dedicated low-field MR systems are suitable for small rodents imaging, opening this technique even to small research units.

  18. Dedicated low-field MRI in mice

    Science.gov (United States)

    Choquet, P.; Breton, E.; Goetz, C.; Marin, C.; Constantinesco, A.

    2009-09-01

    The rationale of this work is to point out the relevance of in vivo MR images of mice obtained using a dedicated low-field system. For this purpose a small 0.1 T water-cooled electro-magnet and solenoidal radio frequency (RF) transmit-receive coils were used. All MR images were acquired in three-dimensional (3D) mode. An isolation cell was designed allowing easy placement of the RF coils and simple delivery of gaseous anesthesia as well as warming of the animal. Images with and without contrast agent were obtained in total acquisition times on the order of half an hour to four hours on normal mice as well as on animals bearing tumors. Typical in plane pixel dimensions range from 200 × 200 to 500 × 500 µm2 with slice thicknesses ranging between 0.65 and 1.50 mm. This work shows that, besides light installation and low cost, dedicated low-field MR systems are suitable for small rodents imaging, opening this technique even to small research units.

  19. Observation-status patients in children's hospitals with and without dedicated observation units in 2011.

    Science.gov (United States)

    Macy, Michelle L; Hall, Matthew; Alpern, Elizabeth R; Fieldston, Evan S; Shanley, Leticia A; Hronek, Carla; Hain, Paul D; Shah, Samir S

    2015-06-01

    Pediatric observation units (OUs) have demonstrated reductions in lengths of stay (LOS) and costs of care. Hospital-level outcomes across all observation-status stays have not been evaluated in relation to the presence of a dedicated OU in the hospital. To compare observation-status stay outcomes in hospitals with and without a dedicated OU. Cross-sectional analysis of hospital administrative data. Observation-status stay outcomes were compared in hospitals with and without a dedicated OU across 4 categories: (1) LOS, (2) standardized costs, (3) conversion to inpatient status, and (4) return care. Observation-status stays in 31 free-standing children's hospitals contributing observation patient data to the Pediatric Health Information System database, 2011. Fifty-one percent of the 136,239 observation-status stays in 2011 occurred in 14 hospitals with a dedicated OU; the remainder were in 17 hospitals without. The percentage of observation-status same-day discharges was higher in hospitals with a dedicated OU compared with hospitals without (23.8 vs 22.1, P hospitals with a dedicated OU (11.06%) compared with hospitals without (9.63%, P hospital-level outcomes. Inclusion of location of care (eg, dedicated OU, inpatient unit, emergency department) in hospital administrative datasets would allow for more meaningful comparisons of models of hospital care. © 2015 Society of Hospital Medicine.

  20. Commercial Grade Item (CGI) dedication - on complex electronic equipment

    International Nuclear Information System (INIS)

    Sohn, Kwang Young; Kim, Joong Han; Koo, In Soo; Lee, Sang Yong

    2008-01-01

    In future more complicated IT-based hardware and software is supposed to used in the safety-grade systems in nuclear power plants. Also there are the efforts to establish the criteria for CGI dedications in NRC and CEC dedication in other standard organizations. The highly complicated components, i.e. CEC should be dedication plans. Thus work to be done in later is to prepare the strategies, plans, guide and procedures that is more specific for CEC dedication

  1. A dedicated fund supports technological innovation

    CERN Document Server

    Katarina Anthony

    2010-01-01

    The Knowledge and Technology Transfer (KTT) Group is calling on CERN Departments to take their technology out of the confines of the laboratory and make it ready for dissemination. For the first time, projects can apply for financial support from the newly established KTT Fund.   Scientific inquiry can lead to unexpected developments for society when researchers apply their expertise for public use. CERN actively encourages this transfer of knowledge and technology and, for the first time, has created a dedicated fund to provide financial support to projects aiming at disseminating their technologies to external audiences. CERN’s technology transfer schemes were formalised in the recent Policy on the Management of Intellectual Property in Technology Transfer, approved in March. Revenues generated by commercial exploitation will be distributed between the members of the team that developed the technology, their Department, and the KTT Fund for reinvestment in further KTT projects. &qu...

  2. Optical Design Using Small Dedicated Computers

    Science.gov (United States)

    Sinclair, Douglas C.

    1980-09-01

    Since the time of the 1975 International Lens Design Conference, we have developed a series of optical design programs for Hewlett-Packard desktop computers. The latest programs in the series, OSLO-25G and OSLO-45G, have most of the capabilities of general-purpose optical design programs, including optimization based on exact ray-trace data. The computational techniques used in the programs are similar to ones used in other programs, but the creative environment experienced by a designer working directly with these small dedicated systems is typically much different from that obtained with shared-computer systems. Some of the differences are due to the psychological factors associated with using a system having zero running cost, while others are due to the design of the program, which emphasizes graphical output and ease of use, as opposed to computational speed.

  3. 47 CFR 69.125 - Dedicated signalling transport.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Dedicated signalling transport. 69.125 Section... (CONTINUED) ACCESS CHARGES Computation of Charges § 69.125 Dedicated signalling transport. (a) Dedicated signalling transport shall consist of two elements, a signalling link charge and a signalling transfer point...

  4. Virtual Machine Scheduling in Dedicated Computing Clusters

    CERN Document Server

    Boettger, Stefan; Zicari, V Roberto

    2014-01-08

    Time-critical applications process a continuous stream of input data and have to meet specific timing constraints. A common approach to ensure that such an application satisfies its constraints is over-provisioning: The application is deployed in a dedicated cluster environment with enough processing power to achieve the target performance for every specified data input rate. This approach comes with a drawback: At times of decreased data input rates, the cluster resources are not fully utilized. A typical use case is the HLT-Chain application that processes physics data at runtime of the ALICE experiment at CERN. From a perspective of cost and efficiency it is desirable to exploit temporarily unused cluster resources. Existing approaches aim for that goal by running additional applications. These approaches, however, a) lack in flexibility to dynamically grant the time-critical application the resources it needs, b) are insufficient for isolating the time-critical application from harmful side-effects i...

  5. A subjective scheduler for subjective dedicated networks

    Science.gov (United States)

    Suherman; Fakhrizal, Said Reza; Al-Akaidi, Marwan

    2017-09-01

    Multiple access technique is one of important techniques within medium access layer in TCP/IP protocol stack. Each network technology implements the selected access method. Priority can be implemented in those methods to differentiate services. Some internet networks are dedicated for specific purpose. Education browsing or tutorial video accesses are preferred in a library hotspot, while entertainment and sport contents could be subjects of limitation. Current solution may use IP address filter or access list. This paper proposes subjective properties of users or applications are used for priority determination in multiple access techniques. The NS-2 simulator is employed to evaluate the method. A video surveillance network using WiMAX is chosen as the object. Subjective priority is implemented on WiMAX scheduler based on traffic properties. Three different traffic sources from monitoring video: palace, park, and market are evaluated. The proposed subjective scheduler prioritizes palace monitoring video that results better quality, xx dB than the later monitoring spots.

  6. Conception of comics dedicated to optics learning

    Science.gov (United States)

    Machemy, Jacques; Bousquet, Bruno

    2015-10-01

    Optics' teaching is commonly based on the use of lessons including several mathematical tools. For example, ray tracing can be described through matrix algebra, and interference and polarization can be supported by the use of complex numbers. Thus, the numerous mathematical descriptions included in the optics' lessons represent a real difficulty for students having insufficient skills in mathematics. Moreover, despite of very impressive optical effects one can observe in real life, e.g. rainbows, their description in optics' courses is often considered as too academic and boring, and finally not really exciting. In this context, we have invented a new type of comics dedicated to optics' learning. Based on a dialogue between two imaginary characters, one considered as the young student and the other one as the old teacher, we have chosen to reduce the role of mathematics and to mix realistic and unrealistic elements in the drawing to complete the explanations faster. Starting from reflection and refraction, the Snell's laws then allow for describing natural phenomena such as mirage and rainbow as well as technical points such as light propagation into an optical fiber and the measurement of the refraction index. The first volume presented here will be evaluated during the fall semester 2015 in different high schools and at university through a linked survey and the students will also get access to an online version while the following parts are in preparation.

  7. Dedicated education unit: implementing an innovation in replication sites.

    Science.gov (United States)

    Moscato, Susan R; Nishioka, Vicki M; Coe, Michael T

    2013-05-01

    An important measure of an innovation is the ease of replication and achievement of the same positive outcomes. The dedicated education unit (DEU) clinical education model uses a collaborative academic-service partnership to develop an optimal learning environment for students. The University of Portland adapted this model from Flinders University, Australia, to increase the teaching capacity and quality of nursing education. This article identifies DEU implementation essentials and reports on the outcomes of two replication sites that received consultation support from the University of Portland. Program operation information, including education requirements for clinician instructors, types of patient care units, and clinical faculty-to-student ratios is presented. Case studies of the three programs suggest the DEU model is adaptable to a range of different clinical settings and continues to show promise as one strategy for addressing the nurse faculty shortage and strengthening academic-clinical collaborations while maintaining quality clinical education for students. Copyright 2013, SLACK Incorporated.

  8. Computerized engineering logic for procurement and dedication processes

    International Nuclear Information System (INIS)

    Tulay, M.P.

    1996-01-01

    This paper summarizes the work performed for designing the system and especially for calculating on-line expected performance and gives some significant results. In an attempt to better meet the needs of operations and maintenance organizations, many nuclear utility procurement engineering groups have simplified their procedures, developed on-line tools for performing the specification of replacement items, and developed relational databases containing part-level information necessary to automate the procurement process. Although these improvements have helped to reduce the engineering necessary to properly specify and accept/dedicate items for nuclear safety-related applications, a number of utilities have recognized that additional long-term savings can be realized by integrating a computerized logic to assist technical procurement engineering personnel

  9. Special Issue Dedication to Stephen H. Schneider

    Directory of Open Access Journals (Sweden)

    Paul Baer

    2011-12-01

    Full Text Available It is with both pleasure and sadness that we dedicate this special climate change issue of Portal to the late Dr. Stephen H. Schneider. Steve, as he was known to his friends and colleagues, was as rare a bird as any he sought out in his passion as a birdwatcher. A brilliant climate scientist, author of countless books and papers, path breaking inter-disciplinarian, eminent public communicator, mentor to dozens of young scholars; the list of roles and adulatory adjectives could fill an IPCC special report. Steve would have appreciated this special issue, with its multidisciplinary approach, and its quest for solutions based on analytical scholarship. He understood better than most the inseparability of normative and descriptive concerns, the need for academics and scientists of all kinds to be involved with public processes of communication, policy design and deliberation. While his last book was called “Science as a Contact Sport,” the unspoken title of his career might have been “Science as a Public Service.” He was endlessly testifying, consulting and giving interviews, and encouraged others to learn to do the same. Notwithstanding a battle with lymphoma in the last decade (chronicled in the wonderful book The Patient from Hell, Steve maintained a frenetic level of activity and was still going strong when he was felled by a pulmonary embolism in July of 2010 at age 65. He leaves behind a legacy embodied in his publications, institutions like the IPCC and the journal Climatic Change, and in the hearts and minds of the countless persons he interacted with, mentored, and loved. Exuberant, passionate, full of warmth and good humor, Steve was a mensch among mensches. He will be sorely missed. Paul Baer, with the assistance of Terry Root and Ian McGregor.

  10. Multimodality Registration without a Dedicated Multimodality Scanner

    Directory of Open Access Journals (Sweden)

    Bradley J. Beattie

    2007-03-01

    Full Text Available Multimodality scanners that allow the acquisition of both functional and structural image sets on a single system have recently become available for animal research use. Although the resultant registered functional/structural image sets can greatly enhance the interpretability of the functional data, the cost of multimodality systems can be prohibitive, and they are often limited to two modalities, which generally do not include magnetic resonance imaging. Using a thin plastic wrap to immobilize and fix a mouse or other small animal atop a removable bed, we are able to calculate registrations between all combinations of four different small animal imaging scanners (positron emission tomography, single-photon emission computed tomography, magnetic resonance, and computed tomography [CT] at our disposal, effectively equivalent to a quadruple-modality scanner. A comparison of serially acquired CT images, with intervening acquisitions on other scanners, demonstrates the ability of the proposed procedures to maintain the rigidity of an anesthetized mouse during transport between scanners. Movement of the bony structures of the mouse was estimated to be 0.62 mm. Soft tissue movement was predominantly the result of the filling (or emptying of the urinary bladder and thus largely constrained to this region. Phantom studies estimate the registration errors for all registration types to be less than 0.5 mm. Functional images using tracers targeted to known structures verify the accuracy of the functional to structural registrations. The procedures are easy to perform and produce robust and accurate results that rival those of dedicated multimodality scanners, but with more flexible registration combinations and while avoiding the expense and redundancy of multimodality systems.

  11. Use of commercial grade item dedication to reduce procurement costs

    International Nuclear Information System (INIS)

    Rosch, F.

    1995-01-01

    In the mid-1980s, the Nuclear Regulatory Industry (NRC) began inspecting utility practices of procuring and dedicating commercial grade items intended for plant safety-related applications. As a result of the industry efforts to address NRC concerns, nuclear utilities have enhanced existing programs and procedures for dedication of commercial grade items. Though these programs were originally enhanced to meet NRC concerns, utilities have discovered that the dedication of commercial grade items can also reduce overall procurement costs. This paper will discuss the enhancement of utility dedication programs and demonstrates how utilities have utilized them to reduce procurement costs

  12. Life Cycle Analysis of Dedicated Nano-Launch Technologies

    Science.gov (United States)

    Zapata, Edgar; McCleskey, Carey (Editor); Martin, John; Lepsch, Roger; Ternani, Tosoc

    2014-01-01

    Recent technology advancements have enabled the development of small cheap satellites that can perform useful functions in the space environment. Currently, the only low cost option for getting these payloads into orbit is through ride share programs - small satellites awaiting the launch of a larger satellite, and then riding along on the same launcher. As a result, these small satellite customers await primary payload launches and a backlog exists. An alternative option would be dedicated nano-launch systems built and operated to provide more flexible launch services, higher availability, and affordable prices. The potential customer base that would drive requirements or support a business case includes commercial, academia, civil government and defense. Further, NASA technology investments could enable these alternative game changing options. With this context, in 2013 the Game Changing Development (GCD) program funded a NASA team to investigate the feasibility of dedicated nano-satellite launch systems with a recurring cost of less than $2 million per launch for a 5 kg payload to low Earth orbit. The team products would include potential concepts, technologies and factors for enabling the ambitious cost goal, exploring the nature of the goal itself, and informing the GCD program technology investment decision making process. This paper provides an overview of the life cycle analysis effort that was conducted in 2013 by an inter-center NASA team. This effort included the development of reference nano-launch system concepts, developing analysis processes and models, establishing a basis for cost estimates (development, manufacturing and launch) suitable to the scale of the systems, and especially, understanding the relationship of potential game changing technologies to life cycle costs, as well as other factors, such as flights per year.

  13. A Life Dedicated to Public Service: The Lady L Story

    Directory of Open Access Journals (Sweden)

    Maribeth P. Bentillo

    2016-05-01

    Full Text Available This study featured how a lady local politician rose to power as a barangay captain. It aimed to: describe her leadership orientation before she became a barangay captain, analyze the factors of her success stories in political leadership, extrapolate her values based on the problems/challenges met in the barangay, unveil her initiatives to address these problems, and interpolate her enduring vision for the future of the barangay. Through a biographical research design, with purposive sampling, a key female informant named as Lady L was chosen with the sole criteria of being a female Barangay Captain of Cebu City. Interview guides were utilized in the generation of Lady L’s biographic information about her political career.Lady L’s experiences in waiting for the perfect time and working in the private sector destined her to have a successful political career enhanced with passion and family influence. Encountering problems concerning basic education and unwanted migrants in Barangay K did not discourage her choice to run for re-election, because of her dedication to public service. Her ways to reach out and collaborate with welfare groups mitigate the problems of parental neglect and informal settlers in her barangay. The story of Lady L implies that in Cebu City, issues arise as a result of the practice of partisan politics, gender issues have minor bearing, and she envisioned a healthy and welleducated barangay, with an improved wellness and child care development.

  14. Energy Secretary Dedicates ESIF at NREL | News | NREL

    Science.gov (United States)

    3 » Energy Secretary Dedicates ESIF at NREL Energy Secretary Dedicates ESIF at NREL September 18 prey. Enlarge image Energy Secretary Ernest Moniz (center) joins NREL Director Dan Arvizu (left) and newest Energy Department supercomputer. The high performance computer inside NREL's new Energy Systems

  15. Dedicated auxiliary power units for Hybrid Electric Vehicles

    NARCIS (Netherlands)

    Mourad, S.; Weijer, C.J.T. van de

    1998-01-01

    The use of a dedicated auxiliary power unit is essential to utilize the potential that hybrid vehicles offer for efficient and ultra-clean transportation. An example of a hybrid project at the TNO Road-Vehicles Research Institute shows the development and the results of a dedicated auxiliary power

  16. Coherence in Professional Education: Does It Foster Dedication and Identification?

    Science.gov (United States)

    Heggen, Kåre; Terum, Lars Inge

    2013-01-01

    This article examines the impact of professional education on students' dedication to and identification with a profession. The premise is that professional education is not only about knowledge acquisition and reasoning but also about attitudes and aspirations. In fostering dedication and identification, students' experiences of relevance seem to…

  17. Editorial: A dedication to Professor Jan Evetts

    Science.gov (United States)

    Weber, Harald; Dew-Hughes, David; Campbell, Archie; Barber, Zoe; Somekh, Rob; Glowacki, Bartek

    2006-03-01

    A few days before the beginning of the 7th European Conference on Applied Superconductivity we learned that Professor Jan Evetts, a pioneer of superconductor research, a brilliant scientist, a wonderful person and a great personal friend, had passed away. We therefore decided to dedicate the 7th European Conference on Applied Superconductivity to the memory of Jan Evetts. The following citation is based on material provided by his former supervisor (D Dew-Hughes) and his closest co-workers in Cambridge. Professor Jan Edgar Evetts (1939-2005) Professor Jan Edgar Evetts (1939-2005) Jan Evetts passed away after losing his second battle with cancer on 24th August 2005. He made an outstanding series of contributions to the science of superconductivity and to the understanding of superconducting materials and was an indefatigable champion of the development of applications of superconductivity. The loss to the superconductivity community is incalculable, as attested by the many communications received from colleagues throughout the world. Jan was born on 31 March 1939, and attended the Dragon School in Oxford, and later Haileybury. He was awarded an exhibition to read Natural Sciences at Pembroke College, Cambridge. He entered the college in 1958 and took his BA degree in 1961. He then undertook a Certificate of Postgraduate Study in Physics under the supervision of Professor Neville Mott. He was the first student to undertake this newly-instituted course; the title of his thesis was `The Resistance of Transition Metals'. In 1962 he joined David Dew-Hughes' superconducting materials research group, along with Archie Campbell and Anant Narlikar. In fact it was Jan's enthusiasm for the proposed course of research that helped convince David that he should follow Professor Alan Cottrell's suggestion to apply metallurgical methodology to the study of the factors that controlled critical current density in the type II superconductors that were then under development for

  18. Dedicated Beamline Facilities for Catalytic Research. Synchrotron Catalysis Consortium (SCC)

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Jingguang [Columbia Univ., New York, NY; Frenkel, Anatoly [Yeshiva Univ., New York, NY (United States); Rodriguez, Jose [Brookhaven National Lab. (BNL), Upton, NY (United States); Adzic, Radoslav [Brookhaven National Lab. (BNL), Upton, NY (United States); Bare, Simon R. [UOP LLC, Des Plaines, IL (United States); Hulbert, Steve L. [Brookhaven National Lab. (BNL), Upton, NY (United States); Karim, Ayman [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Mullins, David R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Overbury, Steve [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-03-04

    Synchrotron spectroscopies offer unique advantages over conventional techniques, including higher detection sensitivity and molecular specificity, faster detection rate, and more in-depth information regarding the structural, electronic and catalytic properties under in-situ reaction conditions. Despite these advantages, synchrotron techniques are often underutilized or unexplored by the catalysis community due to various perceived and real barriers, which will be addressed in the current proposal. Since its establishment in 2005, the Synchrotron Catalysis Consortium (SCC) has coordinated significant efforts to promote the utilization of cutting-edge catalytic research under in-situ conditions. The purpose of the current renewal proposal is aimed to provide assistance, and to develop new sciences/techniques, for the catalysis community through the following concerted efforts: Coordinating the implementation of a suite of beamlines for catalysis studies at the new NSLS-II synchrotron source; Providing assistance and coordination for catalysis users at an SSRL catalysis beamline during the initial period of NSLS to NSLS II transition; Designing in-situ reactors for a variety of catalytic and electrocatalytic studies; Assisting experimental set-up and data analysis by a dedicated research scientist; Offering training courses and help sessions by the PIs and co-PIs.

  19. Historical aspects of meetings, publication series, and digital resources dedicated to echinoderms

    Directory of Open Access Journals (Sweden)

    Alexander Ziegler

    2014-03-01

    Full Text Available Half a century after the first scientific meeting dedicated to marine spiny-skinned animals (Deuterostomia: Echinodermata was held in Washington, DC, we take this opportunity to provide information on a number of historical aspects related to the echinoderm scientific community. Apart from shedding light on the historical origins of modern echinoderm conferences, the present contribution presents photographs taken during the first meeting of echinoderm researchers in 1963 as well as during the first installments of the International Echinoderm Conference and the European Conference on Echinoderms. Furthermore, we provide background information on publication series dedicated solely to the Echinodermata as well as descriptions of selected digital resources that focus on echinoderms. Finally, we present a number of echinoderm conference logos and flyers in addition to selected information about specific echinoderm meetings.

  20. President Roosevelt's 1940 Dedication of the First NCI Building

    Science.gov (United States)

    Watch this video excerpt of the dedication of the National Institute of Health, October 31, 1940. President Roosevelt spoke of the importance of the National Cancer Institute, which would be located in Building 6.

  1. Evaluating the use of dedicated swab for rapid antigen detection ...

    African Journals Online (AJOL)

    Evaluating the use of dedicated swab for rapid antigen detection testing in group a ... African Journal of Clinical and Experimental Microbiology ... Several generations of rapid antigen detection tests (RADTs) have been developed to facilitate ...

  2. Don't Forget About Dedicated Sea Mine Countermeasures

    National Research Council Canada - National Science Library

    Potts, Malcolm H

    2005-01-01

    .... Struggling through the Korean Conflict, the U.S. Navy began a slow improvement of MCM forces leading up to the first Gulf War where experiences led to the conclusion that a well equipped dedicated MCM force structure is essential...

  3. Minimizing Warehouse Space with a Dedicated Storage Policy

    Directory of Open Access Journals (Sweden)

    Andrea Fumi

    2013-07-01

    inevitably be supported by warehouse management system software. On the contrary, the proposed methodology relies upon a dedicated storage policy, which is easily implementable by companies of all sizes without the need for investing in expensive IT tools.

  4. For a few dollars more: Public trust and the case for transporting nuclear waste in dedicated trains

    International Nuclear Information System (INIS)

    Glickman, T.S.; Golding, D.

    1991-01-01

    The debate about the use of dedicated trains for shipping spent fuel and high-level nuclear waste has been going on for the past l5 years. The nuclear industry and its regulatory agencies would like to consider the case closed. The recent passage of the Hazardous Materials Transportation Uniform Act of 1990, however, opens the door once more, giving the railroads and other proponents of dedicated trains another chance to present their case. This paper argues that earlier conclusions favoring regular trains over dedicated trains were based on incomplete cost and risk information and neglected other factors which are not technical, but social and institutional in nature. The paper finds that the additional cost of a dedicated system is lower than previously thought and concludes that it is a small price to pay for reduced public opposition and increased levels of trust

  5. Dedicated Magnetic Resonance Imaging in the Radiotherapy Clinic

    International Nuclear Information System (INIS)

    Karlsson, Mikael; Karlsson, Magnus G.; Nyholm, Tufve; Amies, Christopher; Zackrisson, Bjoern

    2009-01-01

    Purpose: To introduce a novel technology arrangement in an integrated environment and outline the logistics model needed to incorporate dedicated magnetic resonance (MR) imaging in the radiotherapy workflow. An initial attempt was made to analyze the value and feasibility of MR-only imaging compared to computed tomography (CT) imaging, testing the assumption that MR is a better choice for target and healthy tissue delineation in radiotherapy. Methods and Materials: A 1.5-T MR unit with a 70-cm-bore size was installed close to a linear accelerator, and a special trolley was developed for transporting patients who were fixated in advance between the MR unit and the accelerator. New MR-based workflow procedures were developed and evaluated. Results: MR-only treatment planning has been facilitated, thus avoiding all registration errors between CT and MR scans, but several new aspects of MR imaging must be considered. Electron density information must be obtained by other methods. Generation of digitally reconstructed radiographs (DRR) for x-ray setup verification is not straight forward, and reliable corrections of geometrical distortions must be applied. The feasibility of MR imaging virtual simulation has been demonstrated, but a key challenge to overcome is correct determination of the skeleton, which is often needed for the traditional approach of beam modeling. The trolley solution allows for a highly precise setup for soft tissue tumors without the invasive handling of radiopaque markers. Conclusions: The new logistics model with an integrated MR unit is efficient and will allow for improved tumor definition and geometrical precision without a significant loss of dosimetric accuracy. The most significant development needed is improved bone imaging.

  6. Dedicated magnetic resonance imaging in the radiotherapy clinic.

    Science.gov (United States)

    Karlsson, Mikael; Karlsson, Magnus G; Nyholm, Tufve; Amies, Christopher; Zackrisson, Björn

    2009-06-01

    To introduce a novel technology arrangement in an integrated environment and outline the logistics model needed to incorporate dedicated magnetic resonance (MR) imaging in the radiotherapy workflow. An initial attempt was made to analyze the value and feasibility of MR-only imaging compared to computed tomography (CT) imaging, testing the assumption that MR is a better choice for target and healthy tissue delineation in radiotherapy. A 1.5-T MR unit with a 70-cm-bore size was installed close to a linear accelerator, and a special trolley was developed for transporting patients who were fixated in advance between the MR unit and the accelerator. New MR-based workflow procedures were developed and evaluated. MR-only treatment planning has been facilitated, thus avoiding all registration errors between CT and MR scans, but several new aspects of MR imaging must be considered. Electron density information must be obtained by other methods. Generation of digitally reconstructed radiographs (DRR) for x-ray setup verification is not straight forward, and reliable corrections of geometrical distortions must be applied. The feasibility of MR imaging virtual simulation has been demonstrated, but a key challenge to overcome is correct determination of the skeleton, which is often needed for the traditional approach of beam modeling. The trolley solution allows for a highly precise setup for soft tissue tumors without the invasive handling of radiopaque markers. The new logistics model with an integrated MR unit is efficient and will allow for improved tumor definition and geometrical precision without a significant loss of dosimetric accuracy. The most significant development needed is improved bone imaging.

  7. Dedication increases productivity: an analysis of the implementation of a dedicated medical team in the emergency department.

    Science.gov (United States)

    Ramos, Pedro; Paiva, José Artur

    2017-12-01

    In several European countries, emergency departments (EDs) now employ a dedicated team of full-time emergency medicine (EM) physicians, with a distinct leadership and bed-side emergency training, in all similar to other hospital departments. In Portugal, however, there are still two very different models for staffing EDs: a classic model, where EDs are mostly staffed with young inexperienced physicians from different medical departments who take turns in the ED in 12-h shifts and a dedicated model, recently implemented in some hospitals, where the ED is staffed by a team of doctors with specific medical competencies in emergency medicine that work full-time in the ED. Our study assesses the effect of an intervention in a large academic hospital ED in Portugal in 2002, and it is the first to test the hypothesis that implementing a dedicated team of doctors with EM expertise increases the productivity and reduces costs in the ED, maintaining the quality of care provided to patients. A pre-post design was used for comparing the change on the organisational model of delivering care in our medical ED. All emergency medical admissions were tracked in 2002 (classic model with 12-h shift in the ED) and 2005/2006 (dedicated team with full-time EM physicians), and productivity, costs with medical human resources and quality of care measures were compared. We found that medical productivity (number of patients treated per hour of medical work) increased dramatically after the creation of the dedicated team (X 2 KW = 31.135; N = 36; p work reduced both in regular hours and overtime. Moreover, hospitalisation rates decreased and the length of stay in the ED increased significantly after the creation of the dedicated team. Implementing a dedicated team of doctors increased the medical productivity and reduced costs in our ED. Our findings have straightforward implication for Portuguese policymakers aiming at reducing hospital costs while coping with increased ED demand.

  8. A minimum spanning forest based classification method for dedicated breast CT images

    International Nuclear Information System (INIS)

    Pike, Robert; Sechopoulos, Ioannis; Fei, Baowei

    2015-01-01

    Purpose: To develop and test an automated algorithm to classify different types of tissue in dedicated breast CT images. Methods: Images of a single breast of five different patients were acquired with a dedicated breast CT clinical prototype. The breast CT images were processed by a multiscale bilateral filter to reduce noise while keeping edge information and were corrected to overcome cupping artifacts. As skin and glandular tissue have similar CT values on breast CT images, morphologic processing is used to identify the skin based on its position information. A support vector machine (SVM) is trained and the resulting model used to create a pixelwise classification map of fat and glandular tissue. By combining the results of the skin mask with the SVM results, the breast tissue is classified as skin, fat, and glandular tissue. This map is then used to identify markers for a minimum spanning forest that is grown to segment the image using spatial and intensity information. To evaluate the authors’ classification method, they use DICE overlap ratios to compare the results of the automated classification to those obtained by manual segmentation on five patient images. Results: Comparison between the automatic and the manual segmentation shows that the minimum spanning forest based classification method was able to successfully classify dedicated breast CT image with average DICE ratios of 96.9%, 89.8%, and 89.5% for fat, glandular, and skin tissue, respectively. Conclusions: A 2D minimum spanning forest based classification method was proposed and evaluated for classifying the fat, skin, and glandular tissue in dedicated breast CT images. The classification method can be used for dense breast tissue quantification, radiation dose assessment, and other applications in breast imaging

  9. Operating dedicated data centers – is it cost-effective?

    International Nuclear Information System (INIS)

    Ernst, M; Hogue, R; Hollowell, C; Strecker-Kellog, W; Wong, A; Zaytsev, A

    2014-01-01

    The advent of cloud computing centres such as Amazon's EC2 and Google's Computing Engine has elicited comparisons with dedicated computing clusters. Discussions on appropriate usage of cloud resources (both academic and commercial) and costs have ensued. This presentation discusses a detailed analysis of the costs of operating and maintaining the RACF (RHIC and ATLAS Computing Facility) compute cluster at Brookhaven National Lab and compares them with the cost of cloud computing resources under various usage scenarios. An extrapolation of likely future cost effectiveness of dedicated computing resources is also presented.

  10. Operating Dedicated Data Centers - Is It Cost-Effective?

    Science.gov (United States)

    Ernst, M.; Hogue, R.; Hollowell, C.; Strecker-Kellog, W.; Wong, A.; Zaytsev, A.

    2014-06-01

    The advent of cloud computing centres such as Amazon's EC2 and Google's Computing Engine has elicited comparisons with dedicated computing clusters. Discussions on appropriate usage of cloud resources (both academic and commercial) and costs have ensued. This presentation discusses a detailed analysis of the costs of operating and maintaining the RACF (RHIC and ATLAS Computing Facility) compute cluster at Brookhaven National Lab and compares them with the cost of cloud computing resources under various usage scenarios. An extrapolation of likely future cost effectiveness of dedicated computing resources is also presented.

  11. Contrast-enhanced dedicated breast CT detection of invasive breast cancer preceding mammographic diagnosis

    Directory of Open Access Journals (Sweden)

    Nicolas D. Prionas, MD, PhD

    2015-01-01

    Full Text Available Dedicated breast computed tomography (bCT generates high-resolution, three-dimensional images of the pendent uncompressed breast. Intravenous iodinated contrast during bCT provides additional physiologic information. In this case, a 10.0-mm invasive ductal carcinoma was visualized using contrast-enhanced breast CT one year before mammographic detection. Mammography four months before bCT was negative. The bCT contrast enhancement pattern closely matched the dynamic contrast-enhanced MRI obtained after diagnosis. Lesion enhancement at contrast-enhanced breast CT matched previously published enhancement values of breast cancer. Contrast-enhanced dedicated bCT provided high-resolution tomographic images and physiologic contrast enhancement data that facilitated the detection of an early breast cancer.

  12. Systematic and deliberate orientation and instruction for dedicated education unit staff.

    Science.gov (United States)

    Smyer, Tish; Tejada, Marianne Bundalian; Tan, Rhigel Alforque

    2015-03-01

    On the basis of increasing complexity of the health care environment and recommended changes in how nurses are educated to meet these challenges, the University of Nevada Las Vegas, School of Nursing established an academic-practice partnership with Summerlin Hospital Medical Center to develop a dedicated education unit (DEU). When the DEU model was implemented, variables that were not discussed in the literature needed to be addressed. One such challenge was how to impart pedagogy related to clinical teaching to the DEU nursing staff who would be acting as clinical dedicated unit instructors (CDIs). Of chief concern was the evaluation and monitoring of the quality of CDI-student interactions to ensure optimal student learning outcomes. This article addresses the development of a deliberate, systematic approach to the orientation and continued education of CDIs in the DEU. This information will assist other nursing programs as they begin to implement DEUs. Copyright 2015, SLACK Incorporated.

  13. Pseudomonas aeruginosa burn wound infection in a dedicated ...

    African Journals Online (AJOL)

    Background. Pseudomonas aeruginosa infection is a major cause of morbidity in burns patients. There is a paucity of publications dealing with this infection in the paediatric population. We describe the incidence, microbiology and impact of P. aeruginosa infection in a dedicated paediatric burns unit. Methods.

  14. Dedicating time to volunteering : Values, engagement, and commitment to beneficiaries

    NARCIS (Netherlands)

    Shantz, A.; Saksida, T.; Alfes, K.

    2014-01-01

    A moderated mediation model was developed to explain the variation in the amount of time volunteers dedicate to their chosen voluntary cause. Data from 534 volunteers of an international aid and development agency in the United Kingdom revealed a positive relationship between prosocial values and

  15. Commercial Grade Item (CGI) Dedication for Leak Detection Relays

    International Nuclear Information System (INIS)

    KOCH, M.R.; JOHNS, B.R.

    1999-01-01

    This Test Plan provides a test method to dedicate the leak detection relays used on the new Pumping and Instrumentation Control (PIC) skids. The new skids are fabricated on-site. The leak detection system is a safety class system per the Authorization Basis

  16. Spectrograph dedicated to measuring tropospheric trace gas constituents from space

    NARCIS (Netherlands)

    Vries, J. de; Laan, E.C.; Deutz, A.F.; Escudero-Sanz, I.; Bokhove, H.; Hoegee, J.; Aben, I.; Jongma, R.; Landgraf, J.; Hasekamp, O.P.; Houweling, S.; Weele, M. van; Oss, R. van; Oord, G. van den; Levelt, P.

    2005-01-01

    Several organizations in the Netherlands are cooperating to develop user requirements and instrument concepts in the line of SCIAMACHY and OMI but with an increased focus on measuring tropospheric constituents from space. The concepts use passive spectroscopy in dedicated wavelength sections in the

  17. Performance of TCP over UMTS common and dedicated channels

    NARCIS (Netherlands)

    Lo, Anthony; Heijenk, Geert; Bruma, Cezar; Gameiro, A.

    2003-01-01

    Universal Mobile Telecommunications System (UMTS) is a third-generation cellular network that enables high-speed wireless Internet access. This paper investigates the performance of Transmission Control Protocol (TCP) over UMTS utilizing a common and four dedicated transport channels with bit rates

  18. Virginia Tech's College Of Natural Resources Dedicates Cheatham Hall Expansion

    OpenAIRE

    Davis, Lynn

    2003-01-01

    Thanks to funding by private donors, Alyce Cheatham and her family of Portland, Oregon, Virginia Tech's College of Natural Resources will dedicate a much-needed, three-story addition to its current Cheatham Hall on Wednesday, March 19, at 2:30 p.m.

  19. Cost of a dedicated ART clinic | Harling | South African Medical ...

    African Journals Online (AJOL)

    Abstract. Background. The provision of antiretroviral therapy (ART) is being rolled out across South Africa. Little evidence exists on the cost of running clinics for ART provision. Objectives. To determine the cost per patient-month enrolled in an ART programme and per patient-visit for a dedicated, public-sector ART clinic in a ...

  20. Service differentiation in spare parts supply through dedicated stocks

    NARCIS (Netherlands)

    Alvarez, Elisa; van der Heijden, Matthijs C.; Zijm, Willem H.M.

    2012-01-01

    We investigate keeping dedicated stocks at customer sites in addition to stock kept at some central location as a tool for applying service differentiation in spare parts supply. We study the resulting two-echelon system in a multi-item setting, both under backordering and under emergency shipments

  1. The Dedicated Aerosol Retrieval Experiment (DARE): scientific requirements for a dedicated satellite instrument to measure atmospheric aerosols

    NARCIS (Netherlands)

    Decae, R.; Courrèges-Lacoste, G.B.; Leeuw, G. de

    2004-01-01

    DARE (Dedicated Aerosol Retrieval Experiment) is a study to design an instrument for accurate remote sensing of aerosol properties from space. DARE combines useful properties of several existing instruments like TOMS, GOME, ATSR and POLDER. It has a large wavelength range, 330 to 1000 nm, to

  2. Medical Wikis Dedicated to Clinical Practice: A Systematic Review

    Science.gov (United States)

    Llorca, Guy; Letrilliart, Laurent

    2015-01-01

    Background Wikis may give clinician communities the opportunity to build knowledge relevant to their practice. The only previous study reviewing a set of health-related wikis, without specification of purpose or audience, globally showed a poor reliability. Objective Our aim was to review medical wiki websites dedicated to clinical practices. Methods We used Google in ten languages, PubMed, Embase, Lilacs, and Web of Science to identify websites. The review included wiki sites, accessible and operating, having a topic relevant for clinical medicine, targeting physicians or medical students. Wikis were described according to their purposes, platform, management, information framework, contributions, content, and activity. Purposes were classified as “encyclopedic” or “non-encyclopedic”. The information framework quality was assessed based on the Health On the Net (HONcode) principles for collaborative websites, with additional criteria related to users’ transparency and editorial policy. From a sample of five articles per wikis, we assessed the readability using the Flesch test and compared articles according to the wikis’ main purpose. Annual editorial activities were estimated using the Google engine. Results Among 25 wikis included, 11 aimed at building an encyclopedia, five a textbook, three lessons, two oncology protocols, one a single article, and three at reporting clinical cases. Sixteen wikis were specialized with specific themes or disciplines. Fifteen wikis were using MediaWiki software as-is, three were hosted by online wiki farms, and seven were purpose-built. Except for one MediaWiki-based site, only purpose-built platforms managed detailed user disclosures. The owners were ten organizations, six individuals, four private companies, two universities, two scientific societies, and one unknown. Among 21 open communities, 10 required users’ credentials to give editing rights. The median information framework quality score was 6 out of 16

  3. Engine with pulse-suppressed dedicated exhaust gas recirculation

    Science.gov (United States)

    Keating, Edward J.; Baker, Rodney E.

    2016-06-07

    An engine assembly includes an intake assembly, a spark-ignited internal combustion engine, and an exhaust assembly. The intake assembly includes a charge air cooler disposed between an exhaust gas recirculation (EGR) mixer and a backpressure valve. The charge air cooler has both an inlet and an outlet, and the back pressure valve is configured to maintain a minimum pressure difference between the inlet of the charge air cooler and an outlet of the backpressure valve. A dedicated exhaust gas recirculation system is provided in fluid communication with at least one cylinder and with the EGR mixer. The dedicated exhaust gas recirculation system is configured to route all of the exhaust gas from the at least one cylinder to the EGR mixer for recirculation back to the engine.

  4. Dedication of Stotz-Kontakt switches for Spanish utility owners

    International Nuclear Information System (INIS)

    Lopez Vergara, T.; Martin de la Torre, M.; Alminana, J.

    1996-01-01

    The Spanish Utility Owners Group commissioned Empresarios Agrupados to perform the work for the dedication of the S280 series of Stotz-KONTAKT switches and two of its possible accessories. As a results of this process, the components can be used in safety-related applications in the conditions and locations expected. This article describes the different phases of the dedication process: Technical Evaluation considering the application of switches as new or alternative elements, Acceptance Process and Purchasing Documentation. It sets out the main conclusion drawn from each phase. It also includes details of the activities performed by Empresarios Agrupados as part of the seismic qualification of components: selection of the sample to be tested, the definition of electrical tests before and after the seismic test, and the mounting, electrical powering, operating requirements and monitoring of components during seismic tests. (Author)

  5. Preliminary design of a dedicated proton therapy linac

    International Nuclear Information System (INIS)

    Hamm, R.W.; Crandall, K.R.; Potter, J.M.

    1991-01-01

    The preliminary design has been completed for a low current, compact proton linac dedicated to cancer therapy. A 3 GHz side-coupled structure accelerates the beam from a 70 MeV drift tube linac using commercially available S-band rf power systems and accelerating cavities. This significantly reduces the linac cost and allows incremental energies up to 250 MeV. The short beam pulse width and high repetition rate make the linac similar to the high energy electron linacs now used for cancer therapy, yet produce a proton flux sufficient for treatment of large tumors. The high pulse repetition rate permits raster scanning, and the small output beam size and emittance result in a compact isocentric gantry design. Such a linac will reduce the facility and operating costs for a dedicated cancer therapy system

  6. Scintillator performance considerations for dedicated breast computed tomography

    Science.gov (United States)

    Vedantham, Srinivasan; Shi, Linxi; Karellas, Andrew

    2017-09-01

    Dedicated breast computed tomography (BCT) is an emerging clinical modality that can eliminate tissue superposition and has the potential for improved sensitivity and specificity for breast cancer detection and diagnosis. It is performed without physical compression of the breast. Most of the dedicated BCT systems use large-area detectors operating in cone-beam geometry and are referred to as cone-beam breast CT (CBBCT) systems. The large-area detectors in CBBCT systems are energy-integrating, indirect-type detectors employing a scintillator that converts x-ray photons to light, followed by detection of optical photons. A key consideration that determines the image quality achieved by such CBBCT systems is the choice of scintillator and its performance characteristics. In this work, a framework for analyzing the impact of the scintillator on CBBCT performance and its use for task-specific optimization of CBBCT imaging performance is described.

  7. Dedicated data recording video system for Spacelab experiments

    Science.gov (United States)

    Fukuda, Toshiyuki; Tanaka, Shoji; Fujiwara, Shinji; Onozuka, Kuniharu

    1984-04-01

    A feasibility study of video tape recorder (VTR) modification to add the capability of data recording etc. was conducted. This system is an on-broad system to support Spacelab experiments as a dedicated video system and a dedicated data recording system to operate independently of the normal operation of the Orbiter, Spacelab and the other experiments. It continuously records the video image signals with the acquired data, status and operator's voice at the same time on one cassette video tape. Such things, the crews' actions, animals' behavior, microscopic views and melting materials in furnace, etc. are recorded. So, it is expected that experimenters can make a very easy and convenient analysis of the synchronized video, voice and data signals in their post flight analysis.

  8. Entraigues, a system dedicated to industrial radiography interpretation

    International Nuclear Information System (INIS)

    Fleuet, E.; Lavayssiere, B.

    1995-01-01

    Some inspections including radiography are periodically done among the components of a nuclear power plant in order to check their integrity. Today the operator is in charge of acquiring data, of analysing and of quantifying the produced X-ray films. EDF has built a digital system called ENTRAIGUES which aims to help the processing and the interpretation of radiographic images. The hardware of ENTRAIGUES is composed of a digitizer, a dedicated image processor and a PC. The software has been designed to facilitate the analysis of X-ray images. With the inclusion of compression algorithms and automatic image procedures ENTRAIGUES has become a complete tool dedicated to digitization, processing and archiving of nuclear power plant radiographs. (authors). 2 refs

  9. Cost of a dedicated ART clinic | Harling | South African Medical ...

    African Journals Online (AJOL)

    Little evidence exists on the cost of running clinics for ART provision. Objectives. To determine the cost per patient-month enrolled in an ART programme and per patient-visit for a dedicated, public-sector ART clinic in a South African peri-urban setting in 2004/05 and 2005/06, as the clinic moved from a temporary to a ...

  10. Dedicated training in adult education among otolaryngology faculty.

    Science.gov (United States)

    McMains, Kevin C; Peel, Jennifer

    2014-12-01

    Most faculty members undergo ad hoc training in education. This survey was developed to assess the prevalence and type of dedicated training in education received by academic otolaryngology-head and neck surgery (OTO-HNS) faculty in the United States. Survey. An 11-item survey was developed to assess the prevalence of dedicated instruction in education theory and practice, the types of instruction received, and the barriers to receiving instruction. The survey was sent to all OTO-HNS program directors for distribution among their respective faculty. A total of 216 responses were received. Seventy respondents (32.7%) serve as program director, associate program director, or assistant program director in their respective programs. Forty-six respondents (21.8%) had received dedicated training in education. Of the respondents who described the type of education training received, 48.7% participated in didactics/seminar, 35.9% in degree/certificate programs, 10.3% in multimodality training, and 5.1% online training. Among the barriers encountered to participation in instruction in education, time/productivity pressures was the most commonly cited reason (60.2%), followed by not knowing about the opportunity to receive training (36.4%), lack of departmental support (26.2%), lack of available training (22.3%), and the perception that such training would not be useful (7.8%). Presently, only a minority of surveyed academic otolaryngologists in the United States have received any dedicated instruction in the theory and practice of education. Personal, departmental, and institutional barriers exist in many practice environments that hinder otolaryngology faculty from participating in education training. N/A. © 2014 The American Laryngological, Rhinological and Otological Society, Inc.

  11. Quality assurance requirements for dedication process in Angra 1

    Energy Technology Data Exchange (ETDEWEB)

    Baliza, Ana Rosa, E-mail: baliza@eletronuclear.gov.br [Eletrobras Termonuclear S.A. (ELETRONUCLEAR), Angra dos Reis, RJ (Brazil). Departamento GQO.G; Morghi, Youssef, E-mail: ymo@cdtn.br [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)

    2015-07-01

    In Brazil the regulatory body is CNEN (Comissao Nacional de Energia Nuclear), according to its requirements, when there is not a Brazilian standard, the utilities shall follow the requirements of the designer. For Angra 1, the designer is an American company - Westinghouse. So, the requirements for dedication of U.S. NRC (United States Nuclear Regulatory Commission) shall be applied, these requirements are in 10CFR21 - Reporting of Defects and Noncompliance. According to 10CFR21, when applied to nuclear power plants licensed dedication is an acceptance process undertaken to provide reasonable assurance that a commercial grade item to be used as a basic component will perform its intended safety function and, in this respect, is deemed equivalent to an item designed and manufactured under a quality assurance program standard for nuclear power plant. This assurance is achieved by identifying the critical characteristics of the item and verifying their acceptability by inspections, tests, or analyses by the purchaser or third-party dedicating entity. (author)

  12. Prospects of dedicated biodiesel engine vehicles in Malaysia and Indonesia

    International Nuclear Information System (INIS)

    Jayed, M.H.; Masjuki, H.H.; Kalam, M.A.; Mahlia, T.M.I.; Liaquat, A.M.; Husnawan, M.

    2011-01-01

    Petro diplomacy has played its role in last few decades and that makes energy security a major concern worldwide. Rapid climate change and environmental protection is another vital issue to be addressed in recent energy policies. So an alternative carbon neutral transport fuel is a must in new sustainable energy mix. Biodiesel has immense potentiality to be a part of a sustainable energy mix. In this energy scenario, Brazil's success is a role model in utilizing its agro-industry for reducing poverty, greenhouse gas emission and petro-dependency simultaneously. Brazil commercialized bioethanol in mass scale by introducing flexible fuel vehicles in market. This dedicated engine idea moralizes a new concept of dedicated biodiesel engine vehicles for Malaysia and Indonesia. Southeast Asian countries, i.e. Malaysia and Indonesia is the largest producer as well as exporter of palm oil. Growing at highest yield rate among other biodiesel feedstock, palm based biodiesel is a top exported product for this region. This paper will quantify the prospects of a dedicated biodiesel engine vehicle for Malaysia and Indonesia that will initiate palm based biodiesel in fuel supply chain by leapfrogging the barriers of biodiesel utilization by boosting local automobile industry simultaneously. This article will also review on energy scenario of Malaysia and Indonesia and their renewable energy policies and challenges for coming decades. (author)

  13. Quality assurance requirements for dedication process in Angra 1

    International Nuclear Information System (INIS)

    Baliza, Ana Rosa

    2015-01-01

    In Brazil the regulatory body is CNEN (Comissao Nacional de Energia Nuclear), according to its requirements, when there is not a Brazilian standard, the utilities shall follow the requirements of the designer. For Angra 1, the designer is an American company - Westinghouse. So, the requirements for dedication of U.S. NRC (United States Nuclear Regulatory Commission) shall be applied, these requirements are in 10CFR21 - Reporting of Defects and Noncompliance. According to 10CFR21, when applied to nuclear power plants licensed dedication is an acceptance process undertaken to provide reasonable assurance that a commercial grade item to be used as a basic component will perform its intended safety function and, in this respect, is deemed equivalent to an item designed and manufactured under a quality assurance program standard for nuclear power plant. This assurance is achieved by identifying the critical characteristics of the item and verifying their acceptability by inspections, tests, or analyses by the purchaser or third-party dedicating entity. (author)

  14. Methodology for creating dedicated machine and algorithm on sunflower counting

    Science.gov (United States)

    Muracciole, Vincent; Plainchault, Patrick; Mannino, Maria-Rosaria; Bertrand, Dominique; Vigouroux, Bertrand

    2007-09-01

    In order to sell grain lots in European countries, seed industries need a government certification. This certification requests purity testing, seed counting in order to quantify specified seed species and other impurities in lots, and germination testing. These analyses are carried out within the framework of international trade according to the methods of the International Seed Testing Association. Presently these different analyses are still achieved manually by skilled operators. Previous works have already shown that seeds can be characterized by around 110 visual features (morphology, colour, texture), and thus have presented several identification algorithms. Until now, most of the works in this domain are computer based. The approach presented in this article is based on the design of dedicated electronic vision machine aimed to identify and sort seeds. This machine is composed of a FPGA (Field Programmable Gate Array), a DSP (Digital Signal Processor) and a PC bearing the GUI (Human Machine Interface) of the system. Its operation relies on the stroboscopic image acquisition of a seed falling in front of a camera. A first machine was designed according to this approach, in order to simulate all the vision chain (image acquisition, feature extraction, identification) under the Matlab environment. In order to perform this task into dedicated hardware, all these algorithms were developed without the use of the Matlab toolbox. The objective of this article is to present a design methodology for a special purpose identification algorithm based on distance between groups into dedicated hardware machine for seed counting.

  15. Survey VS audit by using method 2 to dedicate commercial grade services

    International Nuclear Information System (INIS)

    Martinez ayucar, F. J.

    2014-01-01

    Since the start of the commercial grade dedications, both 10CFR21 and EPRI documents, plus the dedication of commercial grade components, and the stage of commercial grade dedication of the services contemplated. And recently the NRC through various communications and answers trafficking among other issues the commercial grade dedication service. The NRC has detected repeatedly incorrect application of the survey as a method of commercial grade dedication and instead has done an audit of the program elements of commercial quality. (Author)

  16. Clear-PEM: A dedicated PET camera for improved breast cancer detection

    International Nuclear Information System (INIS)

    Abreu, M. C.; Almeida, P.; Balau, F.; Ferreira, N. C.; Fetal, S.; Fraga, F.; Martins, M.; Matela, N.; Moura, R.; Ortigao, C.; Peralta, L.; Rato, P.; Ribeiro, R.; Rodrigues, P.; Santos, A. I.; Trindade, A.; Varela, J.

    2005-01-01

    Positron emission mammography (PEM) can offer a non-invasive method for the diagnosis of breast cancer. Metabolic images from PEM using 18 F-fluoro-deoxy-glucose, contain unique information not available from conventional morphologic imaging techniques like X-ray radiography. In this work, the concept of Clear-PEM, the system presently developed in the frame of the Crystal Clear Collaboration at CERN, is described. Clear-PEM will be a dedicated scanner, offering better perspectives in terms of position resolution and detection sensitivity. (authors)

  17. Strengthening moral reasoning through dedicated ethics training in dietetic preparatory programs.

    Science.gov (United States)

    Hewko, Sarah J; Cooper, Sarah L; Cummings, Greta G

    2015-01-01

    Moral reasoning skills, associated with the ability to make ethical decisions effectively, must be purposively fostered. Among health professionals, enhanced moral reasoning is linked to superior clinical performance. Research demonstrates that moral reasoning is enhanced through dedicated, discussion-based ethics education offered over a period of 3-12 weeks. Current dietetic students and practicing dietitians seeking to strengthen their moral reasoning skills can undertake elective ethics education. Further research within dietetic preparatory programs is warranted to better inform the development and implementation of ethics courses. Copyright © 2015 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.

  18. Proposed dedicated high pressure beam lines at CHESS

    International Nuclear Information System (INIS)

    Ruoff, A.L.; Vohra, Y.K.; Bassett, W.A.; Batterman, B.W.; Bilderback, D.H.

    1988-01-01

    An instrumentation proposal for dedicated high pressure beam lines at CHESS is described. It is the purpose of this proposed program to provide researchers in high pressure science with beam lines for X-ray diffraction studies in the megabar regime. This will involve radiation from a bending magnet as well as from a wiggler. Examples of the high pressure results up to 2.16 Mbar are shown. Diffraction patterns from bending magnet and wiggler beams are shown and compared. The need for this facility by the high pressure community is discussed. (orig.)

  19. Nuclab Marcoule: a dedicated waste management and dismantling support laboratory

    International Nuclear Information System (INIS)

    Dugne, Olivier; Bec-Espitalier, Lionel; Rosen, Jeremy

    2014-01-01

    Formerly dedicated to plutonium production support, NucLab was renovated to perform a wide range of analyses for dismantling, plant operation and process development activities mainly at Marcoule but also for external clients. The laboratory is a CEA entity in the Nuclear Energy Division. It provides services to several industrial operators (nuclear processes and power plants) in the fields of analytical chemistry, radioactivity measurements, in situ nuclear measurements, decontamination processes, industrial chemistry processes, and waste treatment. NucLab supports research, production, and dismantling activities in all areas of dismantling operations (authors)

  20. Enabling Dedicated, Affordable Space Access Through Aggressive Technology Maturation

    Science.gov (United States)

    Jones, Jonathan E.; Kibbey, Timothy P.; Cobb, C. Brent; Harris, Lawanna L.

    2014-01-01

    A launch vehicle at the scale and price point which allows developers to take reasonable risks with high payoff propulsion and avionics hardware solutions does not exist today. Establishing this service provides a ride through the proverbial technology "valley of death" that lies between demonstration in laboratory and flight environments. NASA's NanoLaunch effort will provide the framework to mature both earth-to-orbit and on-orbit propulsion and avionics technologies while also providing affordable, dedicated access to low earth orbit for cubesat class payloads.

  1. A Dedicated Genetic Algorithm for Localization of Moving Magnetic Objects

    Directory of Open Access Journals (Sweden)

    Roger Alimi

    2015-09-01

    Full Text Available A dedicated Genetic Algorithm (GA has been developed to localize the trajectory of ferromagnetic moving objects within a bounded perimeter. Localization of moving ferromagnetic objects is an important tool because it can be employed in situations when the object is obscured. This work is innovative for two main reasons: first, the GA has been tuned to provide an accurate and fast solution to the inverse magnetic field equations problem. Second, the algorithm has been successfully tested using real-life experimental data. Very accurate trajectory localization estimations were obtained over a wide range of scenarios.

  2. Marble tabula in Belgrade: Commemoration plates dedicated to perished ones

    Directory of Open Access Journals (Sweden)

    Đapović Lasta

    2009-01-01

    Full Text Available There is an ancient Balkans tradition of building commemoration plates dedicated to perished ones. This actually represents twofold belief, one being that a deceased should rest on his/hers own soil and an attempt to mark a place of someone's death. All were performed with an aim to prolong memory and reminiscence of the deceased. In 19th century Serbia and especially so at the beginning of the 20th century it became popular to build such commemoration plates dedicated to soldiers who have died abroad. In the second half of the 20th century, there are sporadic commemoration plates near roads, not as a designation for an unknown grave but to mark down a place where someone has died, most often in a car accident. At the crossroads of the century, however, this custom was very frequent. Belgrade has also seen many of these commemoration plates. The studying of ways and shapes of this custom is the main subject of this paper. The author tries to follow all changes ranging from those induced by the state to those very rare private commemoration plates placed on certain buildings, including those left to decay, or those maintained regularly, on street lights, near cressets at grave yards, flowers, granite plates etc. The paper also discusses possible causes, frequencies and changes related to this custom.

  3. Calibration of a dedicated software for 3D rendering

    International Nuclear Information System (INIS)

    Abrantes, Marcos E.S.; Felix, Warley F.; Veloso, Maria Auxiliadora F.; Universidade Federal de Minas Gerais

    2017-01-01

    With the increasing use of 3D reconstruction techniques, to assist in diagnosis, dedicated programs are being widely used. For this they must be calibrated in order to encounter the values of the real volumes of the human tissues. The purpose of this work is to indicate correction and calibration values for true volumes, read in a 3D reconstruction system dedicated, using DICOM images of Computed Tomography. This work utilized a PMMA thorax phantom associated with the DICOM image and the volume found by a program of a tomograph. The physical volume of the PMMA phantom found was 10359.0 cm³. For the volumes found according to the structures of interest, the values are 11005.5 cm³, 10249.3 cm³ and 10205.1 cm³ and the correction values are -6.2%, +1.1% e +1.5% respectively for tissues: pulmonary, bony and soft tissues. The procedure performed can be used for calibration in other 3D reconstruction programs, observing the necessary corrections and the methodology used. (author)

  4. Procurement Engineering Process for Commercial Grade Item Dedication

    International Nuclear Information System (INIS)

    Park, Jong-Hyuck; Park, Jong-Eun; Kwak, Tack-Hun; Yoo, Keun-Bae; Lee, Sang-Guk; Hong, Sung-Yull

    2006-01-01

    Procurement Engineering Process for commercial grade item dedication plays an increasingly important role in operation management of Korea Nuclear Power Plants. The purpose of the Procurement Engineering Process is the provision and assurance of a high quality and quantity of spare, replacement, retrofit and new parts and equipment while maximizing plant availability, minimizing downtime due to parts unavailability and providing reasonable overall program and inventory cost. In this paper, we will review the overview requirements, responsibilities and the process for demonstrating with reasonable assurance that a procured item for potential nuclear safety related services or other essential plant service is adequate with reasonable assurance for its application. This paper does not cover the details of technical evaluation, selecting critical characteristics, selecting acceptance methods, performing failure modes and effects analysis, performing source surveillance, performing quality surveys, performing special tests and inspections, and the other aspects of effective Procurement Engineering and Commercial Grade Item Dedication. The main contribution of this paper is to provide the provision of an overview of Procurement Engineering Process for commercial grade item

  5. Dedicated OO expertise applied to Run II software projects

    International Nuclear Information System (INIS)

    Amidei, D.

    2000-01-01

    The change in software language and methodology by CDF and D0 to object-oriented from procedural Fortran is significant. Both experiments requested dedicated expertise that could be applied to software design, coding, advice and review. The Fermilab Run II offline computing outside review panel agreed strongly with the request and recommended that the Fermilab Computing Division hire dedicated OO expertise for the CDF/D0/Computing Division joint project effort. This was done and the two experts have been an invaluable addition to the CDF and D0 upgrade software projects and to the Computing Division in general. These experts have encouraged common approaches and increased the overall quality of the upgrade software. Advice on OO techniques and specific advice on C++ coding has been used. Recently a set of software reviews has been accomplished. This has been a very successful instance of a targeted application of computing expertise, and constitutes a very interesting study of how to move toward modern computing methodologies in HEP

  6. Calibration of a dedicated software for 3D rendering

    Energy Technology Data Exchange (ETDEWEB)

    Abrantes, Marcos E.S.; Felix, Warley F.; Veloso, Maria Auxiliadora F., E-mail: marcos.nuclear@yahoo.com.br, E-mail: warleyferreirafelix@gmail.com, E-mail: mdora@nuclear.ufmg.br [Faculdade Ciencias Medicas de Minas Gerais (FCMMG), Belo Horizonte, MG (Brazil); Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG (Brazil). Departamento de Engenharia Nuclear

    2017-11-01

    With the increasing use of 3D reconstruction techniques, to assist in diagnosis, dedicated programs are being widely used. For this they must be calibrated in order to encounter the values of the real volumes of the human tissues. The purpose of this work is to indicate correction and calibration values for true volumes, read in a 3D reconstruction system dedicated, using DICOM images of Computed Tomography. This work utilized a PMMA thorax phantom associated with the DICOM image and the volume found by a program of a tomograph. The physical volume of the PMMA phantom found was 10359.0 cm³. For the volumes found according to the structures of interest, the values are 11005.5 cm³, 10249.3 cm³ and 10205.1 cm³ and the correction values are -6.2%, +1.1% e +1.5% respectively for tissues: pulmonary, bony and soft tissues. The procedure performed can be used for calibration in other 3D reconstruction programs, observing the necessary corrections and the methodology used. (author)

  7. Information

    International Nuclear Information System (INIS)

    Boyard, Pierre.

    1981-01-01

    The fear for nuclear energy and more particularly for radioactive wastes is analyzed in the sociological context. Everybody agree on the information need, information is available but there is a problem for their diffusion. Reactions of the public are analyzed and journalists, scientists and teachers have a role to play [fr

  8. Intelligent urban public transportation for accessibility dedicated to people with disabilities.

    Science.gov (United States)

    Zhou, Haiying; Hou, Kun-Mean; Zuo, Decheng; Li, Jian

    2012-01-01

    The traditional urban public transport system generally cannot provide an effective access service for people with disabilities, especially for disabled, wheelchair and blind (DWB) passengers. In this paper, based on advanced information & communication technologies (ICT) and green technologies (GT) concepts, a dedicated public urban transportation service access system named Mobi+ has been introduced, which facilitates the mobility of DWB passengers. The Mobi+ project consists of three subsystems: a wireless communication subsystem, which provides the data exchange and network connection services between buses and stations in the complex urban environments; the bus subsystem, which provides the DWB class detection & bus arrival notification services; and the station subsystem, which implements the urban environmental surveillance & bus auxiliary access services. The Mobi+ card that supports multi-microcontroller multi-transceiver adopts the fault-tolerant component-based hardware architecture, in which the dedicated embedded system software, i.e., operating system micro-kernel and wireless protocol, has been integrated. The dedicated Mobi+ embedded system provides the fault-tolerant resource awareness communication and scheduling mechanism to ensure the reliability in data exchange and service provision. At present, the Mobi+ system has been implemented on the buses and stations of line '2' in the city of Clermont-Ferrand (France). The experiential results show that, on one hand the Mobi+ prototype system reaches the design expectations and provides an effective urban bus access service for people with disabilities; on the other hand the Mobi+ system is easily to deploy in the buses and at bus stations thanks to its low energy consumption and small form factor.

  9. Intelligent Urban Public Transportation for Accessibility Dedicated to People with Disabilities

    Science.gov (United States)

    Zhou, Haiying; Hou, Kun-Mean; Zuo, Decheng; Li, Jian

    2012-01-01

    The traditional urban public transport system generally cannot provide an effective access service for people with disabilities, especially for disabled, wheelchair and blind (DWB) passengers. In this paper, based on advanced information & communication technologies (ICT) and green technologies (GT) concepts, a dedicated public urban transportation service access system named Mobi+ has been introduced, which facilitates the mobility of DWB passengers. The Mobi+ project consists of three subsystems: a wireless communication subsystem, which provides the data exchange and network connection services between buses and stations in the complex urban environments; the bus subsystem, which provides the DWB class detection & bus arrival notification services; and the station subsystem, which implements the urban environmental surveillance & bus auxiliary access services. The Mobi+ card that supports multi-microcontroller multi-transceiver adopts the fault-tolerant component-based hardware architecture, in which the dedicated embedded system software, i.e., operating system micro-kernel and wireless protocol, has been integrated. The dedicated Mobi+ embedded system provides the fault-tolerant resource awareness communication and scheduling mechanism to ensure the reliability in data exchange and service provision. At present, the Mobi+ system has been implemented on the buses and stations of line ‘2’ in the city of Clermont-Ferrand (France). The experiential results show that, on one hand the Mobi+ prototype system reaches the design expectations and provides an effective urban bus access service for people with disabilities; on the other hand the Mobi+ system is easily to deploy in the buses and at bus stations thanks to its low energy consumption and small form factor. PMID:23112622

  10. Intelligent Urban Public Transportation for Accessibility Dedicated to People with Disabilities

    Directory of Open Access Journals (Sweden)

    Jian Li

    2012-08-01

    Full Text Available The traditional urban public transport system generally cannot provide an effective access service for people with disabilities, especially for disabled, wheelchair and blind (DWB passengers. In this paper, based on advanced information & communication technologies (ICT and green technologies (GT concepts, a dedicated public urban transportation service access system named Mobi+ has been introduced, which facilitates the mobility of DWB passengers. The Mobi+ project consists of three subsystems: a wireless communication subsystem, which provides the data exchange and network connection services between buses and stations in the complex urban environments; the bus subsystem, which provides the DWB class detection & bus arrival notification services; and the station subsystem, which implements the urban environmental surveillance & bus auxiliary access services. The Mobi+ card that supports multi-microcontroller multi-transceiver adopts the fault-tolerant component-based hardware architecture, in which the dedicated embedded system software, i.e., operating system micro-kernel and wireless protocol, has been integrated. The dedicated Mobi+ embedded system provides the fault-tolerant resource awareness communication and scheduling mechanism to ensure the reliability in data exchange and service provision. At present, the Mobi+ system has been implemented on the buses and stations of line ‘2’ in the city of Clermont-Ferrand (France. The experiential results show that, on one hand the Mobi+ prototype system reaches the design expectations and provides an effective urban bus access service for people with disabilities; on the other hand the Mobi+ system is easily to deploy in the buses and at bus stations thanks to its low energy consumption and small form factor.

  11. Special issue dedicated to Professor Johann M. Schepers

    Directory of Open Access Journals (Sweden)

    Gideon P De Bruin

    2006-10-01

    Full Text Available It is a great pleasure for me to have been associated with this special issue of the SA Journal of Industrial Psychology dedicated to Professor Johann M. Schepers. The purpose of the special issue is to honour Professor Schepers for his contributions to the development of Psychology and Industrial Psychology as empirical fields of study in South Africa. The contributors have worked with Professor Schepers as students or colleagues and share his academic interests. The articles reflect his areas of interest and employ analytic techniques taught and championed by him. We are grateful to Professor Schepers for his cooperation throughout this project. Thanks are due to all the contributors and referees.

  12. SR TXRF: performances and perspectives of a dedicated synchrotron beamline

    International Nuclear Information System (INIS)

    Comin, F.; Apostolo, G.

    2000-01-01

    In principle the brilliance of synchrotron radiation x-ray beams combined with a high degree of linear polarization allows to reach at the same time low LLDs, mapping of the impurity distribution and chemical identification for elements as light as Na. The TXRF facility at the European synchrotron radiation facility is installed along a beamline dedicated to industry and is designed to reach ultimate detection limits of 6 x 10 7 at/cm 2 in selected areas, or to map the concentration of contaminants with LLD in the scale 10 9 at/cm 2 . In the present configuration the facility works in vacuum with a single element detector. Loading, unloading and pump down of wafers is completely automatic. Typical DDLs are of few 10 9 at/cm 2 for Na and Al and 10 8 at/cm 2 for transition metals. Absorption spectra (XANES and EXAFS) of TM help in the defining the chemistry of the contaminant. (author)

  13. Study of spear as a dedicated source of synchrotron radiation

    International Nuclear Information System (INIS)

    Cerino, J.; Golde, A.; Hastings, J.; Lindau, I.; Salsburg, B.; Winick, H.; Lee, M.; Morton, P.; Garren, A.

    1977-11-01

    A study was made of the potential of SPEAR as a dedicated source of synchrotron radiation, based on the expectation that SPEAR will become increasingly available for this purpose as PEP, the 18-GeV colliding-beam storage ring now under construction by LBL and SLAC, becomes operational. A synchrotron radiation research program has been underway since May, 1974. Two beam ports capable of serving 9 simultaneous users are now operational. In single-beam multi-bunch operation high currents are possible (225 mA has been achieved and > approximately 300 mA is expected) and the electron beam emittance can be made smaller, resulting in higher source point brightness. Descriptions are given of SPEAR capabilities and of plans to expand the research capability by adding beam runs and by inserting wiggler magnets in SPEAR straight sections

  14. Various dedicated imaging systems for routine nuclear medical applications

    International Nuclear Information System (INIS)

    Bela Kari; Tamas Gyorke; Erno Mako; Laszlo Nagy; Jozsef Turak; Oszkar Partos

    2004-01-01

    The most essential problems of nuclear medical imaging are resolution, signal/noise ratio (S/N) and sensitivity. Nowadays, the vast majority of the Anger system gamma cameras in clinical application are using parallel projection. The main problem of this projection method is the highly dependence of the image quality on the distance from the collimator surface as well as any improvement in the resolution with the distance -i.e. reduction of image blur- significantly reduces sensitivity. The aim of our research and development work was to create imaging geometry, collimator and detector constructions optimized to particular organs (brain, heart, thyroid), where it is simultaneously possible to increase the resolution and sensitivity. Main concept of the imaging geometry construction is based on the size, location and shape of a particular organ. In case of brain SPECT imaging a multiple head (4 heads in cylinder symmetric approximation) arrangement with extra high intrinsic resolution (<2.5 mm) dedicated detector design provide feasible solution for routine clinical application. The imaging system was essentially designed for Tc-99m and I-123 isotopes. The application field can be easily extended for functional small animal research and new born baby studies. Very positive feedbacks were received from both technical (stability and reproducibility of the technical parameters) and clinical sides in the past 2 years routine applications. A unique, novel conception ultra compact dedicated dual head SPECT system has been created only for 2D, 3D nuclear cardiac applications for Tc-99m and T1-201 labeled radio-pharmaceuticals. The two rectangular detectors (with <2.6 mm intrinsic resolution) are mounted fix in 90 degree geometry and move inside the special formed gantry arrangement. The unique and unusual gantry is designed to keep the detector heads as close as possible to the patient, while the patient is not exposed by any moving part. This special construction also

  15. Dedicated Trigger for Highly Ionising Particles at ATLAS

    CERN Document Server

    Katre, Akshay; The ATLAS collaboration

    2015-01-01

    In 2012, a novel strategy was designed to detect signatures of Highly Ionising Particles (HIPs) such as magnetic monopoles, dyons or Q-balls with ATLAS. A dedicated trigger was developed and deployed for proton-proton collisions at a centre of mass energy of 8 TeV. It uses the Transition Radiation Tracker (TRT) system, applying an algorithm distinct from standard tracking ones. The high threshold (HT) readout capability of the TRT is used to distinguish HIPs from other background processes. The trigger requires significantly lower energy depositions in the electromagnetic calorimeters and is thereby capable of probing a larger range of HIP masses and charges. A description of the algorithm for this newly developed trigger is presented, along with a comparitive study of its performance during the 2012 data-taking period with respect to previous efforts.

  16. HIFI - a dedicated HIgh-FIeld diffraction and spectroscopy instrument

    International Nuclear Information System (INIS)

    Steffens, P.; Enderle, M.; Boehm, M.; Roux, S.

    2011-01-01

    The outstanding scientific impact of single-crystal neutron diffraction and spectroscopy in steady state vertical magnetic fields up to 15 T (17 T without dilution fringe) is reflected in numerous high-profile publications. Magnetic fields 30 T - 35 T in vertical geometry allow to address enigmatic questions without equivalence at lower fields. The constraints implied by such magnetic fields demand a specially designed dedicated instrument. Since the vertical field geometry is crucial for single-crystal diffraction as well as spectroscopy, the solid angle of scattered neutrons is restricted, and a high-flux reactor is best suited to host a corresponding instrument. We propose a world-wide unique versatile instrument for diffraction and spectroscopy in vertical steady fields of 30 T. (authors)

  17. Dedicated Education Units: Partnerships for Building Leadership Competency.

    Science.gov (United States)

    Galuska, Lee A

    2015-07-01

    To enable nurses to lead in health care transformation, nursing education must include opportunities for developing leadership, as well as clinical competencies. Dedicated education units (DEUs) provide supportive environments for competency development in undergraduate students. This study's aim was to explore the effects of a DEU experience on the leadership development of baccalaureate nursing students. A mixed-methods design included a quantitative strand, using a quasi-experimental, pretest-posttest, multisite design with control groups and a qualitative strand using focus groups. Students in the DEUs demonstrated significant increases (p leadership behaviors, as measured by the Student Leadership Practice Inventory. Focus group themes illuminate how the experiences of the students contributed to their leadership growth. Findings suggest that the DEU experience may promote enhanced undergraduate leadership competency development. Copyright 2015, SLACK Incorporated.

  18. Dedicated extremity MR imaging of the foot and ankle

    International Nuclear Information System (INIS)

    Hottya, G.A.; Peterfy, C.G.; Uffmann, M.; Haeckl, F.O.; LeHir, P.; Redei, J.; Gindele, A.U.; Dion, E.; Genant, H.K.

    2000-01-01

    The purpose of this review is to provide illustrative examples of diseases of the foot and ankle when imaged with a low-field MR imaging system. A retrospective review of 268 foot and ankle examinations, performed in our institution within the past 3 years with a 0.2-T (Artoscan Esaote, Genoa, Italy) dedicated extremity MR system was done. Additionally, illustrative comparison with conventional radiography and high-field MR imaging is presented in patients in whom these examinations were also performed. Although motion artifact limited the value of a few studies, in the majority of examinations low-field MR imaging provided diagnostic image quality for the full spectrum of disorders affecting the foot and ankle and seemed to be a feasible alternative to high-field MR imaging in establishing an accurate diagnosis. (orig.)

  19. Environmental Sciences Laboratory dedication, February 26-27, 1979

    International Nuclear Information System (INIS)

    Auerbach, S.I.; Millemann, N.T.

    1980-09-01

    The dedication of the new Environmental Sciences Laboratory coincided with the 25th year of the establishment of the science of ecology at Oak Ridge National Laboratory. That quarter century witnessed the evolution of ecology from an obscure, backwater discipline of biology to a broadly used, everyday household word. The transition reflected broad and basic changes in our social and cultural view of the world. This was brought about as a result of the awareness developed in our society of the importance of the environment, coupled with efforts of ecologists and other environmental scientists who identified, clarified, and formulated the issues and challenges of environmental protection for both the lay public and the scientific community. In many respects, the activities in ecology at ORNL were a microcosm of the broader social scene; the particular problems of the environment associated with atomic energy needed to be defined in scientific terms and articulated in both the specific and general sense for a larger audience which was unfamiliar with the field and somewhat alien to its concepts and philosophy. The success of this effort is reflected in the existence of the new Environmental Sciences Laboratory. This dedication volume brings together the thoughts and reflections of many of these scientists whose efforts contributed in a unique and individualistic fashion not only to ORNL but also to the national identification of ecology and its importance to the achievement of our national goals. Their remarks and presentations are not only a pleasant and personally gratifying recapitulation of the past and of ORNL's contributions to ecology but also portend some of the challenges to ecology in the future

  20. Environmental Sciences Laboratory dedication, February 26-27, 1979

    Energy Technology Data Exchange (ETDEWEB)

    Auerbach, S.I.; Millemann, N.T. (eds.)

    1980-09-01

    The dedication of the new Environmental Sciences Laboratory coincided with the 25th year of the establishment of the science of ecology at Oak Ridge National Laboratory. That quarter century witnessed the evolution of ecology from an obscure, backwater discipline of biology to a broadly used, everyday household word. The transition reflected broad and basic changes in our social and cultural view of the world. This was brought about as a result of the awareness developed in our society of the importance of the environment, coupled with efforts of ecologists and other environmental scientists who identified, clarified, and formulated the issues and challenges of environmental protection for both the lay public and the scientific community. In many respects, the activities in ecology at ORNL were a microcosm of the broader social scene; the particular problems of the environment associated with atomic energy needed to be defined in scientific terms and articulated in both the specific and general sense for a larger audience which was unfamiliar with the field and somewhat alien to its concepts and philosophy. The success of this effort is reflected in the existence of the new Environmental Sciences Laboratory. This dedication volume brings together the thoughts and reflections of many of these scientists whose efforts contributed in a unique and individualistic fashion not only to ORNL but also to the national identification of ecology and its importance to the achievement of our national goals. Their remarks and presentations are not only a pleasant and personally gratifying recapitulation of the past and of ORNL's contributions to ecology but also portend some of the challenges to ecology in the future.

  1. Informe

    Directory of Open Access Journals (Sweden)

    Egon Lichetenberger

    1950-10-01

    Full Text Available Informe del doctor Egon Lichetenberger ante el Consejo Directivo de la Facultad, sobre el  curso de especialización en Anatomía Patológica patrocinado por la Kellogg Foundation (Departamento de Patología

  2. Commercial off-the-shelf software dedication process based on the commercial grade survey of supplier

    International Nuclear Information System (INIS)

    Kim, J. Y.; Lee, J. S.; Chon, S. W.; Lee, G. Y.; Park, J. K.

    2000-01-01

    Commercial Off-The-Shelf(COTS) software dedication process can apply to a combination of methods like the hardware commercial grade item dedication process. In general, these methods are : methods 1(special test and inspection), method 2(commercial grade survey of supplier), method 3(source verification), and method 4(acceptance supplier/item performance record). In this paper, the suggested procedure-oriented dedication process on the basis of method 2 for COTS software is consistent with EPRI/TR-106439 and NUREG/CR-6421 requirements. Additional tailoring policy based on code and standards related to COTS software may be also founded in the suggested commercial software dedication process. Suggested commercial software dedication process has been developed for a commercial I and C software dedication who performs COTS qualification according to the dedication procedure

  3. Performance evaluation of a high resolution dedicated breast PET scanner

    Energy Technology Data Exchange (ETDEWEB)

    García Hernández, Trinitat, E-mail: mtrinitat@eresa.com; Vicedo González, Aurora; Brualla González, Luis; Granero Cabañero, Domingo [Department of Medical Physics, ERESA, Hospital General Universitario, Valencia 46014 (Spain); Ferrer Rebolleda, Jose; Sánchez Jurado, Raúl; Puig Cozar Santiago, Maria del [Department of Nuclear Medicine, ERESA, Hospital General Universitario, Valencia 46014 (Spain); Roselló Ferrando, Joan [Department of Medical Physics, ERESA, Hospital General Universitario, Valencia 46014 (Spain); Department of Physiology, University of Valencia, Valencia 46010 (Spain)

    2016-05-15

    Purpose: Early stage breast cancers may not be visible on a whole-body PET scan. To overcome whole-body PET limitations, several dedicated breast positron emission tomography (DbPET) systems have emerged nowadays aiming to improve spatial resolution. In this work the authors evaluate the performance of a high resolution dedicated breast PET scanner (Mammi-PET, Oncovision). Methods: Global status, uniformity, sensitivity, energy, and spatial resolution were measured. Spheres of different sizes (2.5, 4, 5, and 6 mm diameter) and various 18 fluorodeoxyglucose ({sup 18}F-FDG) activity concentrations were randomly inserted in a gelatine breast phantom developed at our institution. Several lesion-to-background ratios (LBR) were simulated, 5:1, 10:1, 20:1, 30:1, and 50:1. Images were reconstructed using different voxel sizes. The ability of experienced reporters to detect spheres was tested as a function of acquisition time, LBR, sphere size, and matrix reconstruction voxel size. For comparison, phantoms were scanned in the DbPET camera and in a whole body PET (WB-PET). Two patients who just underwent WB-PET/CT exams were imaged with the DbPET system and the images were compared. Results: The measured absolute peak sensitivity was 2.0%. The energy resolution was 24.0% ± 1%. The integral and differential uniformity were 10% and 6% in the total field of view (FOV) and 9% and 5% in the central FOV, respectively. The measured spatial resolution was 2.0, 1.9, and 1.7 mm in the radial, tangential, and axial directions. The system exhibited very good detectability for spheres ≥4 mm and LBR ≥10 with a sphere detection of 100% when acquisition time was set >3 min/bed. For LBR = 5 and acquisition time of 7 min the detectability was 100% for spheres of 6 mm and 75% for spheres of 5, 4, and 2.5 mm. Lesion WB-PET detectability was only comparable to the DbPET camera for lesion sizes ≥5 mm when acquisition time was >3 min and LBR > 10. Conclusions: The DbPET has a good

  4. Design and evaluation of the MAMMI dedicated breast PET

    International Nuclear Information System (INIS)

    Moliner, L.; González, A. J.; Soriano, A.; Sánchez, F.; Correcher, C.; Orero, A.; Carles, M.; Vidal, L. F.; Barberá, J.; Caballero, L.; Seimetz, M.; Vázquez, C.; Benlloch, J. M.

    2012-01-01

    Purpose: A breast dedicated positron emission tomography (PET) scanner has been developed based on monolithic LYSO crystals coupled to position sensitive photomultiplier tubes (PSPMTs). In this study, we describe the design of the PET system and report on its performance evaluation. Methods: MAMMI is a breast PET scanner based on monolithic LYSO crystals. It consists of 12 compact modules with a transaxial field of view (FOV) of 170 mm in diameter and 40 mm axial FOV that translates to cover up to 170 mm. The patient lies down in a prone position that facilitates maximum breast elongation. Quantitative performance analysis of the calculated method for the attenuation correction specifically developed for MAMMI, and based on PET image segmentation, has also been conducted in this evaluation. In order to fully determine the MAMMI prototype's performance, we have adapted the measurements suggested for National Electrical Manufacturers Association (NEMA) NU 2-2007 and NU 4-2008 protocol tests, as they are defined for whole-body and small animal PET scanners, respectively. Results: Spatial resolutions of 1.6, 1.8, and 1.9 mm were measured in the axial, radial, and tangential directions, respectively. A scatter fraction of 20.8% was obtained and the maximum NEC was determined to be 25 kcps at 44 MBq. The average sensitivity of the system was observed to be 1% for an energy window of (250 keV–750 keV) and a maximum absolute sensitivity of 1.8% was measured at the FOV center. Conclusions: The overall performance of the MAMMI reported on this evaluation quantifies its ability to produce high quality PET images. Spatial resolution values below 3 mm were measured in most of the FOV. Only the radial component of spatial resolution exceeds the 3 mm at radial positions larger than 60 mm. This study emphasizes the need for standardized testing methodologies for dedicated breast PET systems similar to NEMA standards for whole-body and small animal PET scanners.

  5. Performance evaluation of a high resolution dedicated breast PET scanner

    International Nuclear Information System (INIS)

    García Hernández, Trinitat; Vicedo González, Aurora; Brualla González, Luis; Granero Cabañero, Domingo; Ferrer Rebolleda, Jose; Sánchez Jurado, Raúl; Puig Cozar Santiago, Maria del; Roselló Ferrando, Joan

    2016-01-01

    Purpose: Early stage breast cancers may not be visible on a whole-body PET scan. To overcome whole-body PET limitations, several dedicated breast positron emission tomography (DbPET) systems have emerged nowadays aiming to improve spatial resolution. In this work the authors evaluate the performance of a high resolution dedicated breast PET scanner (Mammi-PET, Oncovision). Methods: Global status, uniformity, sensitivity, energy, and spatial resolution were measured. Spheres of different sizes (2.5, 4, 5, and 6 mm diameter) and various 18 fluorodeoxyglucose ("1"8F-FDG) activity concentrations were randomly inserted in a gelatine breast phantom developed at our institution. Several lesion-to-background ratios (LBR) were simulated, 5:1, 10:1, 20:1, 30:1, and 50:1. Images were reconstructed using different voxel sizes. The ability of experienced reporters to detect spheres was tested as a function of acquisition time, LBR, sphere size, and matrix reconstruction voxel size. For comparison, phantoms were scanned in the DbPET camera and in a whole body PET (WB-PET). Two patients who just underwent WB-PET/CT exams were imaged with the DbPET system and the images were compared. Results: The measured absolute peak sensitivity was 2.0%. The energy resolution was 24.0% ± 1%. The integral and differential uniformity were 10% and 6% in the total field of view (FOV) and 9% and 5% in the central FOV, respectively. The measured spatial resolution was 2.0, 1.9, and 1.7 mm in the radial, tangential, and axial directions. The system exhibited very good detectability for spheres ≥4 mm and LBR ≥10 with a sphere detection of 100% when acquisition time was set >3 min/bed. For LBR = 5 and acquisition time of 7 min the detectability was 100% for spheres of 6 mm and 75% for spheres of 5, 4, and 2.5 mm. Lesion WB-PET detectability was only comparable to the DbPET camera for lesion sizes ≥5 mm when acquisition time was >3 min and LBR > 10. Conclusions: The DbPET has a good performance

  6. A parallel architecture system dedicated to fast numerical calculus

    International Nuclear Information System (INIS)

    Harmanci, A.E.

    1982-04-01

    The project described here is the first result of a careful reflection oriented to the implementation of a machine intended for fast scientific computation, having in mind applications in the field of nuclear reactor safety. The selected structure is a data processing system of the MIMD type (Multiple Instruction, Multiple Data Stream). It is built by generalizing a basic cell constituted by associating an host processor and one or several processors dedicated to numerical computation, both operating alternatively on two areas of a common memory block. The principle of simultaneous operation of a large number of identical resources is used at every level of the structure. The system described here is hence modular and reconfigurable. The number of cells, the size and number of memory blocks may be chosen according to the needs. The communication between processors is carried out through the switching of the allocation of memory blocks. Moreover the numerical processors make the best use of private interconnections for synchronisation and fast data interchange. The present study devoted to the definition of the main hardware structures, will be followed by a simulation phase while suitable software tools will be developed [fr

  7. On Data Transfers Over Wide-Area Dedicated Connections

    Energy Technology Data Exchange (ETDEWEB)

    Rao, Nageswara S. [ORNL; Liu, Qiang [ORNL

    2018-01-01

    Dedicated wide-area network connections are employed in big data and high-performance computing scenarios, since the absence of cross-traffic promises to make it easier to analyze and optimize data transfers over them. However, nonlinear transport dynamics and end-system complexity due to multi-core hosts and distributed file systems make these tasks surprisingly challenging. We present an overview of methods to analyze memory and disk file transfers using extensive measurements over 10 Gbps physical and emulated connections with 0–366 ms round trip times (RTTs). For memory transfers, we derive performance profiles of TCP and UDT throughput as a function of RTT, which show concave regions in contrast to entirely convex regions predicted by previous models. These highly desirable concave regions can be expanded by utilizing large buffers and more parallel flows. We also present Poincar´e maps and Lyapunov exponents of TCP and UDT throughputtraces that indicate complex throughput dynamics. For disk file transfers, we show that throughput can be optimized using a combination of parallel I/O and network threads under direct I/O mode. Our initial throughput measurements of Lustre filesystems mounted over long-haul connections using LNet routers show convex profiles indicative of I/O limits.

  8. Rural model dedicated education unit: partnership between college and hospital.

    Science.gov (United States)

    Harmon, Lisa M

    2013-02-01

    This article describes the pilot project development of a rural model Dedicated Education Unit (DEU) by a rural college nursing program and a rural hospital to increase student nurses' confidence and proficiency and improve recruitment of prepared rural staff nurses. Traditionally, for economies of scale, most student clinical rotations occurred in urban settings with the number of students per clinical instructor allowed by the state board of nursing. College budget constraints negated the placement of fewer than this mandated maximum number of students in a rural hospital with a clinical instructor; moreover, rural hospitals could not accommodate 10 students at one time. Rural nursing students were anxious in the urban settings, and this anxiety precluded learning in many instances. Rural hospitals face higher registered nurse vacancies than urban centers. Of the nurses applying for open positions, many were not prepared for the demands of rural nursing, resulting in increased turnover and high orientation costs. The rural model DEU addressed issues of both the nursing program and the hospital. The design and development of the rural model DEU and the advantages of the partnership for the college nursing program and the hospital are discussed. Initial outcomes and serendipitous findings from the pilot project are also discussed. Copyright 2013, SLACK Incorporated.

  9. AMYPdb: A database dedicated to amyloid precursor proteins

    Directory of Open Access Journals (Sweden)

    Delamarche Christian

    2008-06-01

    Full Text Available Abstract Background Misfolding and aggregation of proteins into ordered fibrillar structures is associated with a number of severe pathologies, including Alzheimer's disease, prion diseases, and type II diabetes. The rapid accumulation of knowledge about the sequences and structures of these proteins allows using of in silico methods to investigate the molecular mechanisms of their abnormal conformational changes and assembly. However, such an approach requires the collection of accurate data, which are inconveniently dispersed among several generalist databases. Results We therefore created a free online knowledge database (AMYPdb dedicated to amyloid precursor proteins and we have performed large scale sequence analysis of the included data. Currently, AMYPdb integrates data on 31 families, including 1,705 proteins from nearly 600 organisms. It displays links to more than 2,300 bibliographic references and 1,200 3D-structures. A Wiki system is available to insert data into the database, providing a sharing and collaboration environment. We generated and analyzed 3,621 amino acid sequence patterns, reporting highly specific patterns for each amyloid family, along with patterns likely to be involved in protein misfolding and aggregation. Conclusion AMYPdb is a comprehensive online database aiming at the centralization of bioinformatic data regarding all amyloid proteins and their precursors. Our sequence pattern discovery and analysis approach unveiled protein regions of significant interest. AMYPdb is freely accessible 1.

  10. CIRCE: A dedicated storage ring for coherent THz synchrotron radiation

    International Nuclear Information System (INIS)

    Byrd, J.M.; Martin, Michael C.; McKinney, W.R.; Munson, D.V.; Nishimura, H.; Robin, D.S.; Sannibale, F.; Schlueter, R.D.; Thur, W.G.; Jung, J.Y.; Wan, W.

    2003-01-01

    We present the concepts for an electron storage ring dedicated to and optimized for the production of stable coherent synchrotron radiation (CSR) over the far-infrared terahertz wavelength range from 200 mm to about one cm. CIRCE (Coherent InfraRed CEnter) will be a 66 m circumference ring located on top of the ALS booster synchrotron shielding tunnel and using the existing ALS injector. This location provides enough floor space for both the CIRCE ring, its required shielding, and numerous beamlines. We briefly outline a model for CSR emission in which a static bunch distortion induced by the synchrotron radiation field is used to significantly extend the stable CSR emission towards higher frequencies. This model has been verified with experimental CSR results. We present the calculated CIRCE photon flux where a gain of 6-9 orders of magnitude is shown compared to existing far-IR sources. Additionally, the particular design of the dipole vacuum chamber has been optimized to allow an excellent transmission of these far-infrared wavelengths. We believe that the CIRCE source can be constructed for a modest cost

  11. Cone-beam micro computed tomography dedicated to the breast.

    Science.gov (United States)

    Sarno, Antonio; Mettivier, Giovanni; Di Lillo, Francesca; Cesarelli, Mario; Bifulco, Paolo; Russo, Paolo

    2016-12-01

    We developed a scanner for micro computed tomography dedicated to the breast (BµCT) with a high resolution flat-panel detector and a microfocus X-ray tube. We evaluated the system spatial resolution via the 3D modulation transfer function (MTF). In addition to conventional absorption-based X-ray imaging, such a prototype showed capabilities for propagation-based phase-contrast and related edge enhancement effects in 3D imaging. The system limiting spatial resolution is 6.2mm -1 (MTF at 10%) in the vertical direction and 3.8mm -1 in the radial direction, values which compare favorably with the spatial resolution reached by mini focus breast CT scanners of other groups. The BµCT scanner was able to detect both microcalcification clusters and masses in an anthropomorphic breast phantom at a dose comparable to that of two-view mammography. The use of a breast holder is proposed in order to have 1-2min long scan times without breast motion artifacts. Copyright © 2016 IPEM. Published by Elsevier Ltd. All rights reserved.

  12. An Embedded System Dedicated to Intervehicle Communication Applications

    Directory of Open Access Journals (Sweden)

    Zhou Haiying

    2010-01-01

    Full Text Available To overcome system latency and network delay is essential for intervehicle communication (IVC applications such as hazard alarming and cooperative driving. This paper proposes a low-cost embedded software system dedicated to such applications. It consists of two basic component layers: an operating system, named HEROS (hybrid event-driven and real-time multitasking operating system, and a communication protocol, named CIVIC (Communication Inter Véhicule Intelligente et Coopérative. HEROS is originally designed for wireless sensor networks (WSNs. It contains a component-based resource-aware kernel and a low-latency tuple-based communication system. Moreover, it provides a configurable event-driven and/or real-time multitasking mechanism for various embedded applications. The CIVIC is an autoconfiguration cooperative IVC protocol. It merges proactive and reactive approaches to speed up and optimize location-based routing discovery with high-mobility nodes. Currently, this embedded system has been implemented and tested. The experiment results show that the new embedded system has low system latency and network delay under the principle of small resource consumption.

  13. TCP Throughput Profiles Using Measurements over Dedicated Connections

    Energy Technology Data Exchange (ETDEWEB)

    Rao, Nageswara S. [ORNL; Liu, Qiang [ORNL; Sen, Satyabrata [ORNL; Towsley, Don [University of Massachusetts, Amherst; Vardoyan, Gayane [University of Massachusetts, Amherst; Kettimuthu, R. [Argonne National Laboratory (ANL); Foster, Ian [University of Chicago

    2017-06-01

    Wide-area data transfers in high-performance computing infrastructures are increasingly being carried over dynamically provisioned dedicated network connections that provide high capacities with no competing traffic. We present extensive TCP throughput measurements and time traces over a suite of physical and emulated 10 Gbps connections with 0-366 ms round-trip times (RTTs). Contrary to the general expectation, they show significant statistical and temporal variations, in addition to the overall dependencies on the congestion control mechanism, buffer size, and the number of parallel streams. We analyze several throughput profiles that have highly desirable concave regions wherein the throughput decreases slowly with RTTs, in stark contrast to the convex profiles predicted by various TCP analytical models. We present a generic throughput model that abstracts the ramp-up and sustainment phases of TCP flows, which provides insights into qualitative trends observed in measurements across TCP variants: (i) slow-start followed by well-sustained throughput leads to concave regions; (ii) large buffers and multiple parallel streams expand the concave regions in addition to improving the throughput; and (iii) stable throughput dynamics, indicated by a smoother Poincare map and smaller Lyapunov exponents, lead to wider concave regions. These measurements and analytical results together enable us to select a TCP variant and its parameters for a given connection to achieve high throughput with statistical guarantees.

  14. Quantification of bronchial dimensions at MDCT using dedicated software

    International Nuclear Information System (INIS)

    Brillet, P.Y.; Fetita, C.I.; Saragaglia, A.; Perchet, D.; Preteux, F.; Beigelman-Aubry, C.; Grenier, P.A.

    2007-01-01

    This study aimed to assess the feasibility of quantification of bronchial dimensions at MDCT using dedicated software (BronCare). We evaluated the reliability of the software to segment the airways and defined criteria ensuring accurate measurements. BronCare was applied on two successive examinations in 10 mild asthmatic patients. Acquisitions were performed at pneumotachographically controlled lung volume (65% TLC), with reconstructions focused on the right lung base. Five validation criteria were imposed: (1) bronchus type: segmental and subsegmental; (2) lumen area (LA)>4 mm 2 ; (3) bronchus length (Lg) > 7 mm; (4) confidence index - giving the percentage of the bronchus not abutted by a vessel - (CI) >55% for validation of wall area (WA) and (5) a minimum of 10 contiguous cross-sectional images fulfilling the criteria. A complete segmentation procedure on both acquisitions made possible an evaluation of LA and WA in 174/223 (78%) and 171/174 (98%) of bronchi, respectively. The validation criteria were met for 56/69 (81%) and for 16/69 (23%) of segmental bronchi and for 73/102 (72%) and 58/102 (57%) of subsegmental bronchi, for LA and WA, respectively. In conclusion, BronCare is reliable to segment the airways in clinical practice. The proposed criteria seem appropriate to select bronchi candidates for measurement. (orig.)

  15. A dedicated pollution tax: The motor for change

    International Nuclear Information System (INIS)

    Stoyke, E.; Stoyke, G.

    1992-01-01

    Carbon taxes coming into effect around the world are predicted to reduce greenhouse gas emissions by 1-6%. Using the punitive approach alone, such taxes will not be sufficiently effective in fighting global climate change. A dedicated pollution tax is proposed in which moderate fees on greenhouse gases and other polluting emissions are balanced by financial incentives for energy efficient retrofitting or non-polluting substitutions. These incentives will vastly accelerate conversion to energy efficient technologies by reducing payback periods to acceptable levels and will lead to a 50-80% reduction in fossil fuel consumption at a profit. Estimated environmental costs of pollutant emissions from coal and natural gas are presented, and the internalization of external costs into energy prices is discussed. Demand reduction provides more environmental benefits than scrubbing of fossil emissions, at less cost. Examples of potential lighting savings in a classroom are presented, and simple payback and savings for a variety of lighting energy efficiency measures are tabulated. The effects of different pollution tax levels on Alberta's coal fired electricity generation are tabulated. 5 refs., 6 figs., 4 tabs

  16. Pancreatic β-cell regeneration: Facultative or dedicated progenitors?

    Science.gov (United States)

    Afelik, Solomon; Rovira, Meritxell

    2017-04-15

    The adult pancreas is only capable of limited regeneration. Unlike highly regenerative tissues such as the skin, intestinal crypts and hematopoietic system, no dedicated adult stem cells or stem cell niche have so far been identified within the adult pancreas. New β cells have been shown to form in the adult pancreas, in response to high physiological demand or experimental β-cell ablation, mostly by replication of existing β cells. The possibility that new β cells are formed from other sources is currently a point of major controversy. Under particular injury conditions, fully differentiated pancreatic duct and acinar cells have been shown to dedifferentiate into a progenitor-like state, however the extent, to which ductal, acinar or other endocrine cells contribute to restoring pancreatic β-cell mass remains to be resolved. In this review we focus on regenerative events in the pancreas with emphasis on the restoration of β-cell mass. We present an overview of regenerative responses noted within the different pancreatic lineages, following injury. We also highlight the intrinsic plasticity of the adult pancreas that allows for inter-conversion of fully differentiated pancreatic lineages through manipulation of few genes or growth factors. Taken together, evidence from a number of studies suggest that differentiated pancreatic lineages could act as facultative progenitor cells, but the extent to which these contribute to β-cell regeneration in vivo is still a matter of contention. Copyright © 2016. Published by Elsevier B.V.

  17. Granular, soft and fuzzy approaches for intelligent systems dedicated to professor Ronald R. Yager

    CERN Document Server

    Filev, Dimitar; Beliakov, Gleb

    2017-01-01

    This book offers a comprehensive report on the state-of-the art in the broadly-intended field of “intelligent systems”. After introducing key theoretical issues, it describes a number of promising models for data and system analysis, decision making, and control. It discusses important theories, including possibility theory, the Dempster-Shafer theory, the theory of approximate reasoning, as well as computing with words, together with novel applications in various areas, such as information aggregation and fusion, linguistic data summarization, participatory learning, systems modeling, and many others. By presenting the methods in their application contexts, the book shows how granular computing, soft computing and fuzzy logic techniques can provide novel, efficient solutions to real-world problems. It is dedicated to Professor Ronald R. Yager for his great scientific and scholarly achievements, and for his long-lasting service to the fuzzy logic, and the artificial and computational intelligence communit...

  18. Dedicated clock/timing-circuit theories of time perception and timed performance.

    Science.gov (United States)

    van Rijn, Hedderik; Gu, Bon-Mi; Meck, Warren H

    2014-01-01

    Scalar Timing Theory (an information-processing version of Scalar Expectancy Theory) and its evolution into the neurobiologically plausible Striatal Beat-Frequency (SBF) theory of interval timing are reviewed. These pacemaker/accumulator or oscillation/coincidence detection models are then integrated with the Adaptive Control of Thought-Rational (ACT-R) cognitive architecture as dedicated timing modules that are able to make use of the memory and decision-making mechanisms contained in ACT-R. The different predictions made by the incorporation of these timing modules into ACT-R are discussed as well as the potential limitations. Novel implementations of the original SBF model that allow it to be incorporated into ACT-R in a more fundamental fashion than the earlier simulations of Scalar Timing Theory are also considered in conjunction with the proposed properties and neural correlates of the "internal clock".

  19. Development of a simple photon emission computed tomography dedicated to the small animal

    International Nuclear Information System (INIS)

    Bekaert, V.

    2006-11-01

    The development of in vivo small animal imaging becomes essential to study human pathologies. The ImaBio project of Institut Pluridisciplinaire Hubert Curien (IPHC) fits in the process of developing new instruments for biomedical applications with the development of a multimodality imaging platform dedicated to small animal imaging (AMISSA). This thesis presents the study, the design and the development of a Single Photon Emission Computed Tomography (SPECT) which will be integrated to the AMISSA platform. The result of these developments is the possibility to obtain the spatial distribution of an injected molecule into the animal. The SPECT technical solutions are based on the acquired knowledge of the institute allowing the conception of a device with cameras adapted to the gamma detection produced by the radiotracers used in single photon imaging. In order to cover the entire of the transverse field of view, four gamma cameras are arranged in a ring around the volume of interest. Each camera consists of 5 individual modules based on a YAP:Ce crystal array, a multi-anode photomultiplier and a dedicated multichannel electronic device. Finally, 20 detection modules were calibrated to give the same result for an identical energy deposit. The data are acquired then process to extract the positions and the energies deposited by gamma photons in the crystals. This last information is then gathered to build the projections. The 3D reconstructed image from the projections is carried out by the sequence of two algorithms, analytical and iterative OS-EM, both modified to take into account the singular geometry of our detection system. Finally, the obtained image is fused with the anatomical information given by the micro Computed Tomography system. (author)

  20. Internet use by parents of children attending a dedicated scoliosis outpatient clinic.

    Science.gov (United States)

    Baker, Joseph F; Devitt, Brian M; Lynch, Sam; Green, Connor J; Byrne, Damien P; Kiely, Patrick J

    2012-10-01

    No information exists on the level of internet use among parents of pediatric patients with scoliosis. The internet may represent a medium through which to provide information to augment the outpatient consultation. The aim of this research was to establish the prevalence of internet use amongst a cohort of parents attending a pediatric scoliosis outpatient clinic. A previously used questionnaire (Baker et al., Eur Spine J, 19:1776-1779, 2010) was distributed to parents attending a dedicated scoliosis outpatient clinic with their children. Demographic data and details about use of the internet were collected. Fifty-eight percent of respondents had used the internet to search for information on scoliosis, and 94 % were interested in a local internet provided information provision. A positive history of corrective surgery and possession of health insurance were independent positive predictors of internet use. As surgeons we need to be aware of our patients' use of the internet, and there is the opportunity to use this medium to provide additional education.

  1. Dedicated medical ion accelerator design study. Final report

    International Nuclear Information System (INIS)

    1977-12-01

    Results and conclusions are reported from a design study for a dedicated medical accelerator. Basing efforts on the current consensus regarding medical requirements, the resulting demands on accelerator and beam delivery systems were analyzed, and existing accelerator technology was reviewed to evaluate the feasibility of meeting these demands. This general analysis was augmented and verified by preparing detailed preliminary designs for sources of therapeutic beams of neutrons, protons and heavy ions. The study indicates that circular accelerators are the most desirable and economical solutions for such sources. Synchrotrons are clearly superior for beams of helium and heavier ions, while synchrotrons and cyclotrons seem equally well suited for protons although they have different strengths and weaknesses. Advanced techniques of beam delivery are of utmost importance in fully utilizing the advantages of particle beams. Several issues are invloved here. First, multi-treatment room arrangements are essential for making optimal use of the high dose rate capabilities of ion accelerators. The design of corresponding beam switching systems, the principles of which are already developed for physics experimental areas, pose no problems. Second, isocentric beam delivery substantially enhances flexibility of dose delivery. After several designs for such devices were completed, it was concluded that high field magnets are necessary to keep size, bulk and cost acceptable. Third, and most important, is the generation of large, homogeneous radiation fields. This is presently accomplished with the aid of scattering foils, occluding rings, collimators, ridge filters, and boluses. A novel approach, three-dimensional beam scanning, was developed here, and the most demanding components of such a system (fast-scanning magnet and power supply) were built and tested

  2. A neurosurgery/stereotactic radiotherapy dedicated PACS for conformal radiotherapy

    International Nuclear Information System (INIS)

    Lefkopoulos, D.; Bocquiault, P.; Levrier, M.; Merienne, L.; Schlienger, M.

    1995-01-01

    To realise conformal cerebral stereotactic irradiations we use a Neurosurgery/stereotactic dedicated PACS between two distant hospitals. It connects the stereotactic neurosurgery planification imaging system NEUROAXIS (Sopelem-Sofretec/Ste Anne Hospital) with the dosimetric TPS ARTEMIS-3D/Dosigray (Tenon Hospital). NEUROAXIS is a computer aided stereotactic biopsies and stereo-electroencephalographies, used by surgeons in operating room. The system determines the precise location data for Talairach radiological equipment (X ray source at 5 meters from film) and the geometry of scanner and MRI stereotactical referentials. It provides a full set of features for lesion localization, geometrical computations, surgical planifications, picture archiving, stereotactic angiography, CT and MRI image processing and networking. It sends images through the French public digital network ISDN (NUMERIS/France Telecom : 2x64 Kbits/s) from Ste Anne to Tenon Hospital. Stereotactic angiographic and CT images are reformatted into the DOSIGRAY image processing environment where 3-D dose distributions, displays and DVHs are computed to determine the optimal treatment. ARTEMIS-3D/Dosigray is a TPS for stereotactic radiotherapy devised by the Tenon Hospital for clinical methodology and 3D dose calculations, optimization software development and the Dosigray company for multimodality imaging, (2D(3D)) computer graphics for dose and anatomical representation and data networking. Communication within the radiation oncology department is provided by local area ETHERNET network, linking heterogeneous systems (Vaxstations-3200; Decstation (5000(240))) by means of different protocols. The works in progress are to send back via the same network the 3-D dose matrix to Neurosurgery department NEUROAXIS system. Our PACS is used since six months to treat patients. It has permitted to improve the treatment quality in comparison with our first version TPS ARTEMIS-3D

  3. How much are the teachers dedicated to their profession and the school in which they work?

    OpenAIRE

    Ovesni, Kristinka; Radović, Vera; Alibabić, Šefika

    2014-01-01

    The paper presents the results of a research of the dedication of teachers to their profession and the institution/school in which they are employed. Dedication is defined as connectedness of the teacher with their own profession and the institution in which they are employed and it shows through normative, affective and continuation forms. The research focused on a scientifically under-researched phenomenon of the teacher's dedication in order to help identifying the problem from the perspec...

  4. High spatial resolution quantitative MR images: an experimental study of dedicated surface coils

    International Nuclear Information System (INIS)

    Gensanne, D; Josse, G; Lagarde, J M; Vincensini, D

    2006-01-01

    previous work, the voxel size was reduced to 0.8 mm 3 , allowing us to detect microstructures such as fibrous septae while preserving precision in T 2 measurements. This paper provides practical information allowing us to perform reliable T 2 quantitative MR micro images. High resolution imaging with dedicated surface coils, which is only well-suited to near surface organs, might lead to highly valuable results in this context, especially to analyse the hypodermis involved in the lipodystrophy seen in patients with human immuno-deficiency virus (HIV)

  5. Management of patients in a dedicated burns intensive care unit (BICU) in a developing country.

    Science.gov (United States)

    Hashmi, Madiha; Kamal, Rehana

    2013-05-01

    In Pakistan the practice of managing extensive burns in dedicated intensive care units is not well established. This audit aims to define the characteristics of the victims of major burns and factors that increase mortality and outcome of the protocol-based management in a dedicated burns intensive care unit (BICU). This prospective audit included all patients admitted to the BICU of Suleiman Dawood Burns Unit in Karachi from 1st September 2002 to 31st August 2011. Demographic information, type and place of burn, total body surface area burn (TBSA), type of organ support provided, length of ICU stay, any associated medical diseases, and out outcome were documented. A total of 1597 patients were admitted to the BICU in 9 years. Median age of the patients was 22 (IQR =32-7). 32% victims were children 50 years old. Male to female ratio was 1.4:1. Fire was the leading cause of burns in adults (64%) and scald burns were most common in (64%) in children. 72.4% of the accidents happened at home, where kitchen was the commonest location (597 cases). Mean TBSA burnt was 32.5% (SD ± 22.95%, 95%CI: 31.36-33.61). 27% patients needed ventilatory support, 4% were dialyzed and split skin graftings were performed in 20% patients. Average length of ICU stay was 10.42 days. Epilepsy, psychiatric illness and drug addiction were not common associations with burns. Overall mortality was 41.30% but it decreased over the years from 75% to 27%. Groups of people most vulnerable to sustain burn are young females getting burnt in the kitchen, young males getting burnt at work, and small children falling in pots of hot water stored for drinking or bathing. TBSA >40%, age >50 years, fire burn and female gender were associated with a higher risk of death. Carefully planned, protocol based management of burn patients by burn teams of dedicated healthcare professionals, even with limited resources reduced mortality. Burn hazard awareness, prevention and educational programmes targeted at the

  6. AURORA BOREALIS: a polar-dedicated European Research Platform

    Science.gov (United States)

    Wolff-Boenisch, Bonnie; Egerton, Paul; Thiede, Joern; Roberto, Azzolini; Lembke-Jene, Lester

    2010-05-01

    global climate change. Chances and challenges rest in securing the construction and operation costs that need a dedicated consortium of interested countries and institutions to help tackling the biggest challenges of the next decades.

  7. A dedicated tool for PET scanner simulations using FLUKA

    International Nuclear Information System (INIS)

    Ortega, P.G.; Boehlen, T.T.; Cerutti, F.; Chin, M.P.W.; Ferrari, A.; Mancini, C.; Vlachoudis, V.; Mairani, A.; Sala, Paola R.

    2013-06-01

    Positron emission tomography (PET) is a well-established medical imaging technique. It is based on the detection of pairs of annihilation gamma rays from a beta+-emitting radionuclide, usually inoculated in the body via a biologically active molecule. Apart from its wide-spread use for clinical diagnosis, new applications are proposed. This includes notably the usage of PET for treatment monitoring of radiation therapy with protons and ions. PET is currently the only available technique for non-invasive monitoring of ion beam dose delivery, which was tested in several clinical pilot studies. For hadrontherapy, the distribution of positron emitters, produced by the ion beam, can be analyzed to verify the correct treatment delivery. The adaptation of previous PET scanners to new environments and the necessity of more precise diagnostics by better image quality triggered the development of new PET scanner designs. The use of Monte Carlo (MC) codes is essential in the early stages of the scanner design to simulate the transport of particles and nuclear interactions from therapeutic ion beams or radioisotopes and to predict radiation fields in tissues and radiation emerging from the patient. In particular, range verification using PET is based on the comparison of detected and simulated activity distributions. The accuracy of the MC code for the relevant physics processes is obviously essential for such applications. In this work we present new developments of the physics models with importance for PET monitoring and integrated tools for PET scanner simulations for FLUKA, a fully-integrated MC particle-transport code, which is widely used for an extended range of applications (accelerator shielding, detector and target design, calorimetry, activation, dosimetry, medical physics, radiobiology, ...). The developed tools include a PET scanner geometry builder and a dedicated scoring routine for coincident event determination. The geometry builder allows the efficient

  8. European Science Notes Information Bulletin. A Dedicated Issue: Biotechnology in Europe and Israel

    Science.gov (United States)

    1989-06-01

    multidisciplinary scientific Other fermented foods, yeasts, vinegar effort to achieve industrial and environmental applica- PASTEUR ERA, 1865-1940...of developing the technology. technology lies in the fermentation industry, and it is the large corporations who are developing and exploiting West...organic acids is considered to be the leading European country in bio- via fermentation . In the postwar period, these strengths technology, followed

  9. CENOZOIC CONTINENTAL RIFTING SYMPOSIUM DEDICATED TO THE MEMORY OF ACADEMICIAN N.A. LOGATCHEV, IRKUTSK, RUSSIA, JUNE 7–11, 2010

    Directory of Open Access Journals (Sweden)

    Eugene V. Sklyarov

    2010-01-01

    Full Text Available The information on the «Cenozoic Continental Rifting» Symposium dedicated to the memory of Academician N.A. Logachev is presented. It was held on June 7–11, 2010 at the Institute of the Earth’s Crust, Irkutsk. The scope of conference is presented.

  10. Dedicated Linac for Radioneurosurgery at the National Institute of Neurology and Neurosurgery of Mexico

    Science.gov (United States)

    Celis-López, Miguel A.; Lárraga-Gutiérrez, José M.

    2003-09-01

    The objective is to present a description and the main clinical applications of this dedicated Linac for benign and malignant tumors in the central nervous system. The Novalis (BrainLab, Germany) is a 6 MV dedicated linac for a single high dose Radiosurgery (RS) and for fractionated doses in Stereotactic Radiotherapy with a high level of precision at the isocenter.

  11. Dedicated Linac for Radioneurosurgery at the National Institute of Neurology and Neurosurgery of Mexico

    International Nuclear Information System (INIS)

    Celis-Lopez, Miguel A.; Larraga-Gutierrez, Jose M.

    2003-01-01

    The objective is to present a description and the main clinical applications of this dedicated Linac for benign and malignant tumors in the central nervous system. The Novalis (BrainLab, Germany) is a 6 MV dedicated linac for a single high dose Radiosurgery (RS) and for fractionated doses in Stereotactic Radiotherapy with a high level of precision at the isocenter

  12. 20 CFR 416.1247 - Exclusion of a dedicated account in a financial institution.

    Science.gov (United States)

    2010-04-01

    ... financial institution. 416.1247 Section 416.1247 Employees' Benefits SOCIAL SECURITY ADMINISTRATION... a dedicated account in a financial institution. (a) General. In determining the resources of an individual (or spouse, if any), the funds in a dedicated account in a financial institution established and...

  13. Personalized estimates of radiation dose from dedicated breast CT in a diagnostic population and comparison with diagnostic mammography

    International Nuclear Information System (INIS)

    Vedantham, Srinivasan; Shi, Linxi; Karellas, Andrew; O'Connell, Avice M; Conover, David L

    2013-01-01

    This study retrospectively analyzed the mean glandular dose (MGD) to 133 breasts from 132 subjects, all women, who participated in a clinical trial evaluating dedicated breast CT in a diagnostic population. The clinical trial was conducted in adherence to a protocol approved by institutional review boards and the study participants provided written informed consent. Individual estimates of MGD to each breast from dedicated breast CT was obtained by combining x-ray beam characteristics with estimates of breast dimensions and fibroglandular fraction from volumetric breast CT images, and using normalized glandular dose coefficients. For each study participant and for the breast corresponding to that imaged with breast CT, an estimate of the MGD from diagnostic mammography (including supplemental views) was obtained from the DICOM image headers for comparison. This estimate uses normalized glandular dose coefficients corresponding to a breast with 50% fibroglandular weight fraction. The median fibroglandular weight fraction for the study cohort determined from volumetric breast CT images was 15%. Hence, the MGD from diagnostic mammography was corrected to be representative of the study cohort. Individualized estimates of MGD from breast CT ranged from 5.7 to 27.8 mGy. Corresponding to the breasts imaged with breast CT, the MGD from diagnostic mammography ranged from 2.6 to 31.6 mGy. The mean (± inter-breast SD) and the median MGD (mGy) from dedicated breast CT exam were 13.9 ± 4.6 and 12.6, respectively. For the corresponding breasts, the mean (± inter-breast SD) and the median MGD (mGy) from diagnostic mammography were 12.4 ± 6.3 and 11.1, respectively. Statistical analysis indicated that at the 0.05 level, the distributions of MGD from dedicated breast CT and diagnostic mammography were significantly different (Wilcoxon signed ranks test, p = 0.007). While the interquartile range and the range (maximum–minimum) of MGD from dedicated breast CT was lower than

  14. Human Resource Development in a Newcomer Country: MNPC’s Experience as a Dedicated Nuclear Energy Programme Implementing Organization (NEPIO)

    International Nuclear Information System (INIS)

    Mohd Zamzam Jaafar

    2014-01-01

    Concluding remarks: The establishment of MNPC as a fully dedicated NEPIO facilitates a focused drive towards implementation of a nuclear energy development program for Malaysia. Now, 3 years after its establishment, MNPC will continue to spearhead and coordinate collaborative national efforts towards enabling a well-informed Government decision on the option of using nuclear power post-2020. Nuclear Power Infrastructure Development Plan (NPIDP) is being prepared by Consultant engaged by MNPC and expected to be completed in Dec 2014 Professionals including stakeholders involved with nuclear power planning and programmeimplementation, could also serve as a pool of experts & personnel to staff relevant future organisations needed for NPP development

  15. Trappist: european project dedicated to an open backbone structure for NDT expertise

    International Nuclear Information System (INIS)

    Nouailhas, B.; Vailhen, O.

    1993-01-01

    Non Destructive Testing (NDT) on critical components such as the reactor vessel, primary coolant pipes and steam generators have already been, and are still the subject of many development concerning the improvement of measuring techniques, data processing and on site operation. The tools developed for these tests are generally closed, difficult to extend and of proprietary type. Productivity could be increased if an open backbone structure common to several types of test were available. Moreover, these components are generally submitted to a test involving a single method. In certain cases, the produced information is an insufficient basis for drawing up a satisfactory diagnosis: the test operator or expert often faces problems in extracting more information from signals that are generally noisy. It may prove necessary to complete the inspection with another NDT method based on different principles in order to obtain better performances. It is then by combining the information obtained by two complementary methods that it will be possible to draw up a more reliable diagnosis. These components have also a complex shape. In the case of ultrasonic testing, the accurate following of probe paths requires 3D representation of the geometry, as it is built, to position and display the data obtained from the inspection. To take these geometric constraints into account, it is imperative to use computer tools allowing the three-dimensional representation of the reconstructed information on the components' actual geometry. This specific difficulty, which has long been appreciated, is the subject of developments resulting to industrial products that are more or less satisfactory. The aim of the European Project TRAPPIST (Race Program) is to study an open backbone structure. A mock-up of an analysis station dedicated to NDT expertise will be built and evaluated with specific examples. (authors). 6 figs., 1 ref

  16. Dedicated monitoring and machinery protection systems on reciprocating compressors

    Energy Technology Data Exchange (ETDEWEB)

    Grande, Alvaro; Wenisch, Markus [Hoerbiger Ventilwerke GmbH and Co KG, Wien (Austria); Jacobs, Denis [HOERBIGER do Brasil Industria de Equipamentos, Cajamar, SP (Brazil)

    2012-07-01

    Growing demands on reciprocating compressors (recips) in the process gas industry require particular solutions for machinery protection and performance monitoring systems. Compared to rotating equipment, monitoring systems for recips have to consider the special mechanical and physical characteristics, such as oscillating masses, variable vibration behaviour and varying operating conditions. Furthermore, they provide valuable information about the performance of cylinder related components allowing the operator the optimization of efficiency and availability, and therefore increase production. (author)

  17. 3D dose imaging for arc therapy techniques by means of Fricke gel dosimetry and dedicated Monte Carlo simulations

    International Nuclear Information System (INIS)

    Valente, Mauro; Castellano, Gustavo; Sosa, Carlos

    2008-01-01

    Full text: Radiotherapy is one of the most effective techniques for tumour treatment and control. During the last years, significant developments were performed regarding both irradiation technology and techniques. However, accurate 3D dosimetric techniques are nowadays not commercially available. Due to their intrinsic characteristics, traditional dosimetric techniques like ionisation chamber, film dosimetry or TLD do not offer proper continuous 3D dose mapping. The possibility of using ferrous sulphate (Fricke) dosimeters suitably fixed to a gel matrix, along with dedicated optical analysis methods, based on light transmission measurements for 3D absorbed dose imaging in tissue-equivalent materials, has become great interest in radiotherapy. Since Gore et al. showed in 1984 that the oxidation of ferrous ions to ferric ions still happen even when fixing the ferrous sulphate solution to a gelatine matrix, important efforts have been dedicated in developing and improving real continuous 3D dosimetric systems based on Fricke solution. The purpose of this work is to investigate the capability and suitability of Fricke gel dosimetry for arc therapy irradiations. The dosimetric system is mainly composed by Fricke gel dosimeters, suitably shaped in form of thin layers and optically analysed by means of visible light transmission measurements, acquiring sample images just before and after irradiation by means of a commercial flatbed-like scanner. Image acquisition, conversion to matrices and further analysis are accomplished by means of dedicated developed software, which includes suitable algorithms for optical density differences calculation and corresponding absorbed dose conversion. Dedicated subroutines allow 3D dose imaging reconstruction from single layer information, by means of computer tomography-like algorithms. Also, dedicated Monte Carlo (PENELOPE) subroutines have been adapted in order to achieve accurate simulation of arc therapy irradiation techniques

  18. Aurel Sandulescu—a life dedicated to nuclear physics

    Science.gov (United States)

    Liotta, R. J.

    2013-02-01

    leaders of Romanian physics. It is in recognition of his contribution to physics, especially nuclear physics, as well as his work for Romanian science that this School is organized in his honour, on the occasion of his 80th birthday. I cannot finish this short account without mentioning the person that accompanied Aurel Sandulescu through all his life, his wife of more than fifty years, Violeta. She also was an exceptional person. In her youth she was a very dedicated sporty girl, very athletic, very courageous, very fair and, above all, very generous. These qualities remained with her throughout her life. With deep sorrow I learnt that she passed away three months ago, still youthful and enthusiastic. R J Liotta

  19. Dedicated researcher brings cancer care to rural communities

    Directory of Open Access Journals (Sweden)

    Sharan Bhuller

    2016-10-01

    that lack reliable clean water or electricity. It is an incredibly cost-effective option for low-resource countries seeking to develop national cervical cancer screening and treatment programs according to PATH.“Both projects were completed successfully and brought out research conclusions in the form of national and international publications,” Dr. Asthana says. In addition to the projects, she had also developed health education materials to create cervical cancer awareness among the women of rural Indian community, while providing training to auxiliary nurses and midwives for cervical cancer screening.Dr. Asthana graduated with a degree in Bachelor of Medicine and Bachelor of Surgery from King George Medical College (KGMC, Lucknow, Uttar Pradesh, India, before pursuing her Doctor of Medicine (MD in Community Medicine from Ganesh Shankar Vidyarthi Memorial (GSVM Medical College, Kanpur, India.  Throughout her career, she has published over 40 articles in national and international journals. As a result of her hard work and dedication toward the medical field, she has been awarded first prizes for oral presentation in international conferences such as Indian Cancer Congress (ICC 2014 and Asia Oceania Research Organisation on Genital Infections and Neoplasia (AOGIN 2012.She is an active member of various scientific associations and societies such as the Indian Association for Cancer Research (IACR, Indian Society for Medical Statistics (ISMS, Indian Association of Preventive and Social Medicine (IAPSM, and International Epidemiological Association (IEA. In her effort to provide impactful messages via research publications, she is currently working on remodeling the cancer registry data, which includes a diversified field for incidence of childhood cancer, breast and cervical cancer, trends of major cancer, cancer burden in Northeast of India, among other things.According to Dr. Asthana, her vision is the utilization of voluminous cancer registry data to produce

  20. Dedicated detectors for surface studies by Moessbauer spectroscopy

    International Nuclear Information System (INIS)

    Bibicu, I.; Rogalski, M.S.; Nicolescu, G.

    2001-01-01

    Moessbauer spectroscopy is a nuclear resonance method largely utilized in solid state studies. Following resonant nuclear absorption, gamma radiations, conversion X-rays, conversion or Auger electrons are emitted. By detection of gamma radiations information about the sample as a whole are obtained while by detection of electrons or X radiation one obtains data on the surface layer. Our laboratory was among the firsts to produce and use flow gas proportional detectors for surface studies by Moessbauer spectroscopy. Four types of detectors were devised: - detectors for electron detection (90% He + 10% CH 4 ); - detectors for conversion X-ray detection (90% Ar + 10% CH 4 ); - detectors for electrons or internal conversion X rays; - detectors for simultaneous detection of electrons and conversion X rays emitted from the same source. All detectors allow simultaneous Moessbauer measurements both for surface and volume for a given sample. Details of construction are presented for the four types of detectors

  1. A solid-state dedicated circularly polarized luminescence spectrophotometer: Development and application.

    Science.gov (United States)

    Harada, Takunori; Hayakawa, Hiroshi; Watanabe, Masayuki; Takamoto, Makoto

    2016-07-01

    A new solid-state dedicated circularly polarized luminescence (CPL) instrument (CPL-200CD) was successfully developed for measuring true CPL spectra for optically anisotropic samples on the basis of the Stokes-Mueller matrix approach. Electric components newly installed in the CPL-200CD include a pulse motor-driven sample rotation holder and a 100 kHz lock-in amplifier to achieve the linearly polarized luminescence measurement, which is essential for obtaining the true CPL signal for optically anisotropic samples. An acquisition approach devised for solid-state CPL analysis reduces the measurement times for a data set by ca. 98% compared with the time required in our previous method. As a result, the developed approach is very effective for samples susceptible to light-induced degradation. The theory and implementation of the method are described, and examples of its application to a CPL sample with macroscopic anisotropies are provided. An important advantage of the developed instrument is its ability to obtain molecular information for both excited and ground states because circular dichroism measurements can be performed by switching the monochromatic light to white light without rearrangement of the sample.

  2. Use of other industry standards to facilitate the procurement and dedication of commercial-grade items

    International Nuclear Information System (INIS)

    Beard, R.L.; Rosch, F.C.; Sanwarwalla, M.H.; Tjernlund, R.M.

    1994-01-01

    Nuclear utilities are embarking on innovative approaches for reducing costs in all aspects of engineering, operation, maintenance, and procurement to produce power cheaply and efficiently and remain competitive with other power producers. In the area of procurement, utilities are increasingly obtaining commercial-grade items for use in safety-related applications. This trend is occurring because of lack of suppliers capable or willing to meet 10 CFR 21 and 10 CFR 50 App. B requirements and because of the absence of original equipment suppliers or the spiraling cost associated with procuring items' basic components safety-related from original suppliers. Utilities have been looking at ways to reduce procurement costs. One promising means to reduce costs is to utilize information provided in other nonnuclear industry standards regarding the specification, control, manufacture, and acceptance of the critical characteristics required of the item to perform its design function. A task force was instituted under the sponsorship of the Electric Power Research Institute to investigate the feasibility of using items manufactured to other industry standards in nuclear safety-related applications. This investigation looked at a broad spectrum of available industry standards pertaining to the design, function, manufacture, and testing of items and determined that some standards are more useful than others. This paper discusses the results of this investigation and how credit from the controls exercised for items manufactured to certain existing industry standards can be taken to minimize dedication costs

  3. Implementation and Setup of a System Dedicated Logbook based on ELisA

    CERN Document Server

    Van Tonder, Raynette

    2016-01-01

    ELisA is a web tool used by the ATLAS community as a daily logbook facility in order to record and share information concerning the experiment's operation and deployment. A few subsystems, notably the FTK subsystem, of the ATLAS experiment would like to setup a logbook based on the ELisA logbook for their own private usage. This new logbook would be completely separated from the main ATLAS logbook and will only be accessed from the general public network. In this project the implementation and setup of the ELisA based logbook will be discussed as well as various modifications that were made to the new logbook. These modifications were specified by the FTK users in order to make the logbook relevant to the FTK subsystem. Once the logbook was functioning as expected and the users were satisfied with the modifications, the FTK logbook was installed on a FTK dedicated machine where it is currently being used by members of the FTK group.

  4. GAMIFICATION. SOLUTIONS DEDICATED TO TOURISM INDUSTRY AND THEIR USE IN ROMANIA

    Directory of Open Access Journals (Sweden)

    Mihaela Filofteia S. TUTUNEA

    2017-06-01

    Full Text Available Mobile technologies, applications and solutions in continuous development allowed the creation of a real individual mobile infrastructure and the generation of a new mobile-based client profile to whom companies must continuously adapt. Tourism is one of the most adaptive industries to the tendencies of experiential interactions of the potential client. In case of users of mobile devices, mobile apps and mobile games were easily associated with a background of leisure and entertainment offered by tourism services. For tourism companies the new challenge was to identify new and innovative solutions that offer the advantage of differentiation on the concerned market; thus they conceived adaptive marketing strategies centred on mix of tools that include mobile and travel games and that have brought positive results generating the possibility of integrating and extending them through new gamification solutions. During the last years, the gamification market has recorded an important increase, companies specialised in the development of these solutions extending their offer to cover all types of activities. Starting from these aspects, we considered useful the implementation of a study covering two facets: on one hand, identifying the offer of gamification solutions dedicated to the tourism industry, on the other hand, identifying the Romanian tourists’ demand in their quality of users of these solutions. We consider that the results obtained from the study can offer important sets of information to tourism companies, companies developing gamification solutions and to users of mobile devices in their role as tourists.

  5. Development of a dedicated peptide tandem mass spectral library for conservation science.

    Science.gov (United States)

    Fremout, Wim; Dhaenens, Maarten; Saverwyns, Steven; Sanyova, Jana; Vandenabeele, Peter; Deforce, Dieter; Moens, Luc

    2012-05-30

    In recent years, the use of liquid chromatography tandem mass spectrometry (LC-MS/MS) on tryptic digests of cultural heritage objects has attracted much attention. It allows for unambiguous identification of peptides and proteins, and even in complex mixtures species-specific identification becomes feasible with minimal sample consumption. Determination of the peptides is commonly based on theoretical cleavage of known protein sequences and on comparison of the expected peptide fragments with those found in the MS/MS spectra. In this approach, complex computer programs, such as Mascot, perform well identifying known proteins, but fail when protein sequences are unknown or incomplete. Often, when trying to distinguish evolutionarily well preserved collagens of different species, Mascot lacks the required specificity. Complementary and often more accurate information on the proteins can be obtained using a reference library of MS/MS spectra of species-specific peptides. Therefore, a library dedicated to various sources of proteins in works of art was set up, with an initial focus on collagen rich materials. This paper discusses the construction and the advantages of this spectral library for conservation science, and its application on a number of samples from historical works of art. Copyright © 2012 Elsevier B.V. All rights reserved.

  6. Evaluation of tilted cone-beam CT orbits in the development of a dedicated hybrid mammotomograph

    International Nuclear Information System (INIS)

    Madhav, P; Crotty, D J; Tornai, M P; McKinley, R L

    2009-01-01

    A compact dedicated 3D breast SPECT-CT (mammotomography) system is currently under development. In its initial prototype, the cone-beam CT sub-system is restricted to a fixed-tilt circular rotation around the patient's pendant breast. This study evaluated stationary-tilt angles for the CT sub-system that will enable maximal volumetric sampling and viewing of the breast and chest wall. Images of geometric/anthropomorphic phantoms were acquired using various fixed-tilt circular and 3D sinusoidal trajectories. The iteratively reconstructed images showed more distortion and attenuation coefficient inaccuracy from tilted cone-beam orbits than from the complex trajectory. Additionally, line profiles illustrated cupping artifacts in planes distal to the central plane of the tilted cone-beam, otherwise not apparent for images acquired with complex trajectories. This indicates that undersampled cone-beam data may be an additional cause of cupping artifacts. High-frequency objects could be distinguished for all trajectories, but their shapes and locations were corrupted by out-of-plane frequency information. Although more acrylic balls were visualized with a fixed-tilt and nearly flat cone-beam at the posterior of the breast, 3D complex trajectories have less distortion and more complete sampling throughout the reconstruction volume. While complex trajectories would ideally be preferred, negatively fixed-tilt source-detector configuration demonstrates minimally distorted patient images.

  7. Diffraction-based overlay measurement on dedicated mark using rigorous modeling method

    Science.gov (United States)

    Lu, Hailiang; Wang, Fan; Zhang, Qingyun; Chen, Yonghui; Zhou, Chang

    2012-03-01

    Diffraction Based Overlay (DBO) is widely evaluated by numerous authors, results show DBO can provide better performance than Imaging Based Overlay (IBO). However, DBO has its own problems. As well known, Modeling based DBO (mDBO) faces challenges of low measurement sensitivity and crosstalk between various structure parameters, which may result in poor accuracy and precision. Meanwhile, main obstacle encountered by empirical DBO (eDBO) is that a few pads must be employed to gain sufficient information on overlay-induced diffraction signature variations, which consumes more wafer space and costs more measuring time. Also, eDBO may suffer from mark profile asymmetry caused by processes. In this paper, we propose an alternative DBO technology that employs a dedicated overlay mark and takes a rigorous modeling approach. This technology needs only two or three pads for each direction, which is economic and time saving. While overlay measurement error induced by mark profile asymmetry being reduced, this technology is expected to be as accurate and precise as scatterometry technologies.

  8. Dedication to Professor Hazel Prichard BSc, PhD, MBA (1954-2017)

    Science.gov (United States)

    Hall, Ian; Maier, Wolfgang; Barnes, Stephen J.

    2017-11-01

    The final section of this special issue of GCA on highly siderophile elements is dedicated to Professor Hazel Prichard (see Fig. 1) who sadly passed away in Cardiff on 1st January, 2017, after a brave battle with cancer.

  9. A dedicated storage ring for Far-IR coherent synchrotron radiation at the ALS

    International Nuclear Information System (INIS)

    Barry, W.C.; Baptist, K.M.; Benjegerdes, R.J.; Biocca, A.K.; Byrd, J.M.; Byrne, W.E.; Cambie, D.; Chin, M.J.; Harkins, J.P.; Kwiatkowski, S.; Li, D.; Marks, S.; Martin, M.C.; McKinney, W.R.; Munson, D.V.; Nishimura, H.; Paterson, J.A.; Plate, D.W.; Rex, K.R.; Robin, D.S.; Rossi, S.L.; Sannibale, F.; Scarvie, T.; Schlueter, R.D.; Steier, C.A.; Stover, G.D.; Thur, W.G.; Jung, J.Y.; Zbasnik, J.P.

    2002-01-01

    We present the concepts for a storage ring dedicated to and optimized for the production of stable coherent synchrotron radiation (CSR) over the far-infrared wavelength range from about 200 microns to 1 mm

  10. Revision to dedicated short range communication roadside equipment specification - RSU 4.1.Bench Test Plan.

    Science.gov (United States)

    2017-04-28

    The document describes the overall process for evaluating Dedicated Short Range Communication (DSRC) Roadside Units (RSU) against USDOT RSU Specification 4.1 in preparation for field evaluation. The Test Cases contained in this document only evaluate...

  11. Does the SBCT Intelligence Structure Need a Dedicated ACE/Fusion Cell?

    National Research Council Canada - National Science Library

    Sisemore, James

    2004-01-01

    ... a dedicated division level fusion cell. This question is considered because of the doctrinal lack of a Stryker Division headquarters to serve as the link between a SBCT and a corps headquarters...

  12. A dedicated line-processor as used at the SHF

    International Nuclear Information System (INIS)

    Bevan, A.V.; Hatley, R.W.; Price, D.R.; Rankin, P.

    1985-01-01

    A hardwired trigger processor was used at the SLAC Hybrid Facility to find evidence for charged tracks originating from the fiducial volume of a 40'' rapidcycling bubble chamber. Straight-line projections of these tracks in the plane perpendicular to the applied magnetic field were searched for using data from three sets of proportional wire chambers (PWC). This information was made directly available to the processor by means of a special digitizing card. The results memory of the processor simulated read-only memory in a 168/E processor and was accessible by it. The 168/E controlled the issuing of a trigger command to the bubble chamber flash tubes. The same design of digitizer card used by the line processor was incorporated into the 168/E, again as read only memory, which allowed it access to the raw data for continual monitoring of trigger integrity. The design logic of the trigger processor was verified by running real PWC data through a FORTRAN simulation of the hardware. This enabled the debugging to become highly automated since a step by step, computer controlled comparison of processor registers to simulation predictions could be made

  13. Think Tanks Dedicated to Security Affairs: The Dynamic of Networks

    Directory of Open Access Journals (Sweden)

    Maria do Rosario Vaz

    1997-12-01

    Full Text Available La agrupación de recursos y el desarrollo de posturas comunes son dos aspectos importantes de la actual estrategia de redes entre institutos dedicados al estudio de la seguridad y la política exterior. También, los think tanks y otros centros pueden usar las redes como un instrumento para fomentar el diálogo y construir confianza en actividades de prevención de conflictos, dada la necesidad de que se colabore con diferentes actores procedentes de distintas especialidades. La dinámica de redes, afirma la autora, va de lo personal e informal a lo formal e institucional. El fenómeno de redes es resultado tanto de las actuales tendencias hacia la integración como de las demandas transnacionales de seguridad. Las redes, mediante el desarrollo de contactos entre las sociedades civiles (una vez organizadas en entidades que funcionan, pueden participar en la reflexión de los temas de seguridad. Los inputs colectivos de los think tanks, las ONG, los Gobiernos y otras organizaciones pueden contribuir a crear un lenguaje colectivo en asuntos de seguridad, reducir los riesgos de las percepciones incorrectas y avanzar en los procesos de prevención de conflictos.

  14. An instrument dedicated for modelling of pulmonary radiotherapy

    International Nuclear Information System (INIS)

    Niezink, Anne G.H.; Dollekamp, Nienke J.; Elzinga, Harriet J.; Borger, Denise; Boer, Eduard J.H.; Ubbels, Jan F.; Woltman-van Iersel, Marleen; Leest, Annija H.D. van der; Beijert, Max; Groen, Harry J.M.; Kraan, Jan; Hiltermann, Thijo J.N.; Wekken, Anthonie J. van der; Putten, John W.G. van; Rutgers, Steven R.; Pieterman, Remge M.; Hosson, Sander M. de; Roenhorst, Anke W.J.; Langendijk, Johannes A.; Widder, Joachim

    2015-01-01

    Background and purpose: Radiotherapy plays a pivotal role in lung cancer treatment. Selection of patients for new (radio)therapeutic options aiming at improving outcomes requires reliable and validated prediction models. We present the implementation of a prospective platform for evaluation and development of lung radiotherapy (proPED-LUNG) as an instrument enabling multidimensional predictive modelling. Materials and methods: ProPED-LUNG was designed to comprise relevant baseline and follow up data of patients receiving pulmonary radiotherapy with curative intent. Patient characteristics, diagnostic and staging information, treatment parameters including full dose–volume-histograms, tumour control, survival, and toxicity are scored. Besides physician-rated data, a range of patient-rated data regarding symptoms and health-related quality-of-life are collected. Results: After 18 months of accrual, 315 patients have been included (accrual rate, 18 per month). Of the first hundred patients included, 70 received conformal (chemo)radiotherapy and 30 underwent stereotactic radiotherapy. Compliance at 3 and 6 months follow-up was 96–100% for patient-rated, and 81–94% for physician-rated assessments. For data collection, 0.4 FTE were allocated in a 183 FTE department (0.2%). Conclusions: ProPED-LUNG is feasible with high compliance rates and yields a large amount of high quality prospective disease-related, treatment-related, patient- and physician-rated data which can be used to evaluate new developments in pulmonary radiotherapy

  15. The RadioAstron Dedicated DiFX Distribution

    Directory of Open Access Journals (Sweden)

    Gabriele Bruni

    2016-10-01

    Full Text Available Distributed FX-architecture (DiFX is a software Very Long Baseline Interferometry (VLBI correlator currently adopted by several main correlation sites around the globe. After the launch of the RadioAstron Space-VLBI mission in 2011, an extension was necessary to handle processing of an orbiting antenna, to be correlated with supporting ground arrays. Here, we present a branch of the main DiFX distribution (2.4, uploaded on the publicly available repository during July 2016, that the Max Planck Institute for Radio Astronomy (MPIfR developed to process data of the three key active galactic nuclei (AGN-imaging RadioAstron science projects, as well as part of the AGN survey project, and General Observing Time (GOT projects proposed since Announcement of Opportunity 2 (AO-2, July 2014–July 2015. It can account for general relativistic correction of an orbiting antenna with variable position/velocity, providing a routine to convert the native RadioAstron Data Format (RDF format to the more common Mark5 B (M5B. The possibility of introducing a polynomial clock allows one to mitigate the effects of spacecraft acceleration terms in near-perigee observations. Additionally, since for the first time polarimetry on space-baselines is available thanks to RadioAstron, this DiFX branch allows one to include the spacecraft orientation information at the correlation stage, in order to perform proper polarization calibration during data reduction. Finally, a fringe-finding algorithm able to manage an arbitrarily large fringe-search window is included, allowing one to increase the search space normally adopted by common software packages like HOPS.

  16. STSE: Spatio-Temporal Simulation Environment Dedicated to Biology

    Directory of Open Access Journals (Sweden)

    Gerber Susanne

    2011-04-01

    Full Text Available Abstract Background Recently, the availability of high-resolution microscopy together with the advancements in the development of biomarkers as reporters of biomolecular interactions increased the importance of imaging methods in molecular cell biology. These techniques enable the investigation of cellular characteristics like volume, size and geometry as well as volume and geometry of intracellular compartments, and the amount of existing proteins in a spatially resolved manner. Such detailed investigations opened up many new areas of research in the study of spatial, complex and dynamic cellular systems. One of the crucial challenges for the study of such systems is the design of a well stuctured and optimized workflow to provide a systematic and efficient hypothesis verification. Computer Science can efficiently address this task by providing software that facilitates handling, analysis, and evaluation of biological data to the benefit of experimenters and modelers. Results The Spatio-Temporal Simulation Environment (STSE is a set of open-source tools provided to conduct spatio-temporal simulations in discrete structures based on microscopy images. The framework contains modules to digitize, represent, analyze, and mathematically model spatial distributions of biochemical species. Graphical user interface (GUI tools provided with the software enable meshing of the simulation space based on the Voronoi concept. In addition, it supports to automatically acquire spatial information to the mesh from the images based on pixel luminosity (e.g. corresponding to molecular levels from microscopy images. STSE is freely available either as a stand-alone version or included in the linux live distribution Systems Biology Operational Software (SB.OS and can be downloaded from http://www.stse-software.org/. The Python source code as well as a comprehensive user manual and video tutorials are also offered to the research community. We discuss main concepts

  17. STSE: Spatio-Temporal Simulation Environment Dedicated to Biology.

    Science.gov (United States)

    Stoma, Szymon; Fröhlich, Martina; Gerber, Susanne; Klipp, Edda

    2011-04-28

    Recently, the availability of high-resolution microscopy together with the advancements in the development of biomarkers as reporters of biomolecular interactions increased the importance of imaging methods in molecular cell biology. These techniques enable the investigation of cellular characteristics like volume, size and geometry as well as volume and geometry of intracellular compartments, and the amount of existing proteins in a spatially resolved manner. Such detailed investigations opened up many new areas of research in the study of spatial, complex and dynamic cellular systems. One of the crucial challenges for the study of such systems is the design of a well stuctured and optimized workflow to provide a systematic and efficient hypothesis verification. Computer Science can efficiently address this task by providing software that facilitates handling, analysis, and evaluation of biological data to the benefit of experimenters and modelers. The Spatio-Temporal Simulation Environment (STSE) is a set of open-source tools provided to conduct spatio-temporal simulations in discrete structures based on microscopy images. The framework contains modules to digitize, represent, analyze, and mathematically model spatial distributions of biochemical species. Graphical user interface (GUI) tools provided with the software enable meshing of the simulation space based on the Voronoi concept. In addition, it supports to automatically acquire spatial information to the mesh from the images based on pixel luminosity (e.g. corresponding to molecular levels from microscopy images). STSE is freely available either as a stand-alone version or included in the linux live distribution Systems Biology Operational Software (SB.OS) and can be downloaded from http://www.stse-software.org/. The Python source code as well as a comprehensive user manual and video tutorials are also offered to the research community. We discuss main concepts of the STSE design and workflow. We

  18. Quality of pediatric abdominal CT scans performed at a dedicated children's hospital and its referring institutions: a multifactorial evaluation

    International Nuclear Information System (INIS)

    Snow, Aisling; Milliren, Carly E.; Graham, Dionne A.; Callahan, Michael J.; MacDougall, Robert D.; Robertson, Richard L.; Taylor, George A.

    2017-01-01

    Pediatric patients requiring transfer to a dedicated children's hospital from an outside institution may undergo CT imaging as part of their evaluation. Whether this imaging is performed prior to or after transfer has been shown to impact the radiation dose imparted to the patient. Other quality variables could also be affected by the pediatric experience and expertise of the scanning institution. To identify differences in quality between abdominal CT scans and reports performed at a dedicated children's hospital, and those performed at referring institutions. Fifty consecutive pediatric abdominal CT scans performed at outside institutions were matched (for age, gender and indication) with 50 CT scans performed at a dedicated freestanding children's hospital. We analyzed the scans for technical parameters, report findings, correlation with final clinical diagnosis, and clinical utility. Technical evaluation included use of intravenous and oral contrast agents, anatomical coverage, number of scan phases and size-specific dose estimate (SSDE) for each scan. Outside institution scans were re-reported when the child was admitted to the children's hospital; they were also re-interpreted for this study by children's hospital radiologists who were provided with only the referral information given in the outside institution's report. Anonymized original outside institutional reports and children's hospital admission re-reports were analyzed by two emergency medicine physicians for ease of understanding, degree to which the clinical question was answered, and level of confidence in the report. Mean SSDE was lower (8.68) for children's hospital scans, as compared to outside institution scans (13.29, P = 0.03). Concordance with final clinical diagnosis was significantly lower for original outside institution reports (38/48, 79%) than for both the admission and study children's hospital reports (48/50, 96%; P = 0.005). Children's hospital admission reports were rated higher

  19. Optical calibration protocol for an x-ray and optical multimodality tomography system dedicated to small-animal examination

    International Nuclear Information System (INIS)

    Da Silva, Anabela; Leabad, Mehdi; Driol, Clemence; Bordy, Thomas; Debourdeau, Mathieu; Dinten, Jean-Marc; Peltie, Philippe; Rizo, Philippe

    2009-01-01

    A small-animal multimodality tomography system dedicated to the coregistration of fluorescence optical signal and x-ray measurements has been developed in our laboratory. The purpose of such a system is to offer the possibility of getting in vivo anatomical and functional information simultaneously. Moreover, anatomical measurements can be used as a regularization factor to achieve more accurate reconstructions of the biodistribution of fluorochromes and to speed up treatment. A dedicated acquisition protocol has been established, and the methodology of the reconstruction of the three-dimensional distribution of the biomarkers under cylindrical geometry consistent with classic computed tomography has been implemented. A phantom study was conducted to evaluate and to fix the parameters for the coregistration. These test experiments were reproduced by considering anesthetized mice that had thin glass tubes containing fluorochromes inserted into their esophagus. The instrument is also used for an in vivo biological study conducted on mice with lung tumors, tagged with near-infrared optical probes (targeting probes such as Transferin-AlexaFluor750)

  20. A merged-beam setup at SOLEIL dedicated to photoelectron–photoion coincidence studies on ionic species

    Energy Technology Data Exchange (ETDEWEB)

    Bizau, J.M., E-mail: jean-marc.bizau@u-psud.fr [Institut des Sciences Moléculaires d’Orsay (ISMO), CNRS, Univ. Paris Paris-Sud, Université Paris-Saclay, F-91405 Orsay (France); Synchrotron SOLEIL, L’Orme des Merisiers, Saint-Aubin, BP 48, F-91192 Gif-sur-Yvette Cedex (France); Cubaynes, D. [Institut des Sciences Moléculaires d’Orsay (ISMO), CNRS, Univ. Paris Paris-Sud, Université Paris-Saclay, F-91405 Orsay (France); Synchrotron SOLEIL, L’Orme des Merisiers, Saint-Aubin, BP 48, F-91192 Gif-sur-Yvette Cedex (France); Guilbaud, S.; El Eassan, N.; Al Shorman, M.M.; Bouisset, E.; Guigand, J.; Moustier, O.; Marié, A.; Nadal, E. [Institut des Sciences Moléculaires d’Orsay (ISMO), CNRS, Univ. Paris Paris-Sud, Université Paris-Saclay, F-91405 Orsay (France); Robert, E.; Nicolas, C. [Synchrotron SOLEIL, L’Orme des Merisiers, Saint-Aubin, BP 48, F-91192 Gif-sur-Yvette Cedex (France); Miron, C. [Synchrotron SOLEIL, L’Orme des Merisiers, Saint-Aubin, BP 48, F-91192 Gif-sur-Yvette Cedex (France); Extreme Light Infrastructure—Nuclear Physics, “Horia Hulubei” National Institute for Physics and Nuclear Engineering, 30 Reactorului Street, RO-077125 Măgurele, Jud. Ilfov (Romania)

    2016-07-15

    Highlights: • Description of a merged-beam setup at SOLEIL synchrotron radiation facility. • Unique setup of this kind allowing photoelectron spectroscopy on ionic species. • Use of electron-ion coincidence to reduce the background. • Examples on the photoionization of Xe{sup 5+} multiply-charged ion. - Abstract: We describe the merged-beam setup permanently installed on a dedicated optical branch of the PLEIADES beamline at SOLEIL, the French synchrotron radiation facility in St-Aubin, delivering photons in the 10–1000 eV photon energy range. The setup is designed both for photoion and photoelectron spectroscopy experiments on atomic and molecular ions. Ion spectrometry is dedicated to the determination of absolute single and multiple photoionization cross sections. Electron spectroscopy brings additional information on the non-radiative decay of inner-vacancies produced in the photoionization processes and allows for the determination of partial cross sections. Efficient reduction of the background in the electron spectra is achieved by the use of the electron-ion coincidence technique. Examples of photoion and photoelectron spectra are given for the Xe{sup 5+} ion.

  1. Extended defect related energy loss in CVD diamond revealed by spectrum imaging in a dedicated STEM

    International Nuclear Information System (INIS)

    Bangert, U.; Harvey, A.J.; Schreck, M.; Hoermann, F.

    2005-01-01

    This article aims at investigations of the low EEL region in the wide band gap system diamond. The advent of the UHV Enfina electron energy loss spectrometer combined with Digital Micrograph acquisition and processing software has made reliable detection of absorption losses below 10 eV possible. Incorporated into a dedicated STEM this instrumentation allows the acquisition of spectral information via spectrum maps (spectrum imaging) of sample areas hundreds of nanometers across, with nanometers pixel sizes, adequate spectrum statistics and 0.3 eV energy resolution, in direct correlation with microstructural features in the mapping area. We aim at discerning defect related losses at band gap energies, and discuss different routes to simultaneously process and analyse the spectra in a map. This involves extracting the zero loss peak from each spectrum and constructing ratio maps from the intensities in two energy windows, one defect related and one at a higher, crystal bandstructure dominated energy. This was applied to the residual spectrum maps and their first derivatives. Secondly, guided by theoretical EEL spectra calculations, the low loss spectra were fitted by a series of gaussian distributions. Pixel maps were constructed from amplitude ratios of gaussians, situated in the defect and the unaffected energy regime. The results demonstrate the existence of sp 2 -bonded carbon in the vicinity of stacking faults and partial dislocations in CVD diamond as well as additional states below conduction band, tailing deep into the band gap, at a node in a perfect dislocation. Calculated EEL spectra of shuffle dislocations give similar absorption features at 5-8 eV, and it is thought that this common feature is due to sp 2 -type bonding

  2. Clinical utility of scintimammography: From the Anger-camera to new dedicated devices

    Energy Technology Data Exchange (ETDEWEB)

    Schillaci, Orazio [Department of Biopathology and Diagnostic Imaging, University ' Tor Vergata' , Viale G. Mazzini 121, 00195 Rome (Italy)]. E-mail: oschil@tiscali.it; Danieli, Roberta [Department of Biopathology and Diagnostic Imaging, University ' Tor Vergata' , Viale G. Mazzini 121, 00195 Rome (Italy); Romano, Pasquale [Department of Biopathology and Diagnostic Imaging, University ' Tor Vergata' , Viale G. Mazzini 121, 00195 Rome (Italy); Cossu, Elsa [Department of Biopathology and Diagnostic Imaging, University ' Tor Vergata' , Viale G. Mazzini 121, 00195 Rome (Italy); Simonetti, Giovanni [Department of Biopathology and Diagnostic Imaging, University ' Tor Vergata' , Viale G. Mazzini 121, 00195 Rome (Italy)

    2006-12-20

    Scintimammography is a functional imaging technique which uses a radiation detection camera to detect radionuclide tracers in the patient's breasts. Tracers are designed to accumulate in tumours more than in healthy tissue: the most used are Tc-99 m sestamibi and Tc-99 m tetrofosmin. Scintimammography is useful in some clinical indications as an adjunct to mammography: it is recommended for those lesions where additional information is required to reach a definitive diagnosis. Patients with dubious mammograms may benefit from this test, as well as women with dense breasts or with implants. Scintimammography is a valuable diagnostic tool also in patients with locally advanced breast cancer for monitoring and predicting response to neoadjuvant chemotherapy. Nevertheless, using an Anger-camera this technique shows a high sensitivity only for cancers >1 cm. Since other modalities are increasingly employed for the early identification of small abnormalities, the issue of detecting small cancers is critical for the future development and clinical utility of breast imaging with radiopharmaceuticals. The use of high-resolution cameras dedicated for breast imaging is the best option to improve the detection of small cancers: they allow higher flexibility in patient positioning, and the availability of mammography-like projections. Moreover, the detector can be placed directly in contact with the breast allowing a mild compression with reduction of the breast's thickness, thus increasing the target-to-background ratio and the sensitivity. These new devices have the potential of increasing the total number of breast scintigraphies performed thereby enhancing the role of nuclear medicine in breast cancer imaging.

  3. Dedication for Safety-Related Fuses used in Class-1E Power System

    International Nuclear Information System (INIS)

    Hong, Younghee

    2014-01-01

    The safety-related fuses used in class-1E power system provide overcurrent protection for electrical system and isolate the class 1E circuit from a fault or overload condition. These days, the number of nuclear grade suppliers has been reduced. Accordingly, commercial grade, instead of safety-related, fuses are procured and used in the utilities through the dedication process. Therefore, this paper introduces the commercial grade fuse dedication process/engineering and how to assure the quality requirements with this process and engineering. The fuses used in class-1E power system are to protect overcurrent and to isolate fault. Therefore the fuse for acceptance in order to improve the quality and reliability for commercial grade fuses shall be dedicated. The fuse resistance value may be useful as an indicator of acceptance. The current carrying capacity test can change the fuse performance properties. Therefore these critical characteristics are needed for additional review and analysis with fuse manufactures

  4. Modeling and sizing the coil in boost converters dedicated to photovoltaic sources

    Science.gov (United States)

    Atik, Lotfi; Fares, Mohammed Amine; Zaraket, Jean; Bachir, Ghalem; Aillerie, Michel

    2018-05-01

    The coil is a very important element in a wide range of power electrical systems as such as those used in converter or inverter dedicated to extract and to adapt the value and the shape of the intensity and the voltage delivered by renewable energy sources. Thus, knowing its behavior in converters is paramount to obtain a maximum conversion efficiency and reliability. In this context, this paper presents a global study of a DC/DC boost converter dedicated to photovoltaic sources based on the modeling of the behavior of the coil or the inductance as a function of the switching frequency.

  5. Dedicated workspaces: Faster resumption times and reduced cognitive load in sequential multitasking

    DEFF Research Database (Denmark)

    Jeuris, Steven; Bardram, Jakob Eyvind

    2016-01-01

    Studies show that virtual desktops have become a widespread approach to window management within desktop environments. However, despite their success, there is no experimental evidence of their effect on multitasking. In this paper, we present an experimental study incorporating 16 participants...... to perform the same tasks. Results show that adopting virtual desktops as dedicated workspaces allows for faster task resumption (10 s faster on average) and reduced cognitive load during sequential multitasking. Within our experiment the majority of users already benefited from using dedicated workspaces...

  6. A Dedication to the 70 th Anniversary of Late Prof. Dmitrii A. Krivolutsky

    Directory of Open Access Journals (Sweden)

    Badamdorj Bayartogtokh

    2009-12-01

    Full Text Available This work is dedicated to the 70 th birthday of late professor and corresponding member of the Russian Academy of Sciences, D. A. Krivolutsky, a man of exceptional abilities and experiences, and one of the leading acarologists and soil zoologists in Russia. He was one of the scientists who led to the development of modern acarology and soil zoology in Russia and some other countries through his scienti fi c, teaching and organizational activities. He has dedicated his scienti fi c career to discovering and describing biological diversity of Russia and other countries of the former Soviet Union.

  7. A system dedicated to the viewing and handling of tomographic images obtained by magnetic resonance

    International Nuclear Information System (INIS)

    Slaets, Joan F.W.; Almeida, Lirio O.B.; Traina, Agma J.M.

    1992-01-01

    The present work describes the development of a dedicated system to be used in visualization and manipulation of a MR images. The graphics environment as well as the tool kit were developed for the dedicated TMS34010 based hardware. The developed software offers a compact kernel with primitives to support the creation and manipulation windows and menus directly in 'C' language. This work is fundamental for the implementation of a user friendly interface build to operate and visualize tomographic images. This tools are essential for the selection an archiving of images planes as used in clinical applications. (author)

  8. Measurement of the neutrino velocity with the OPERA detector in the CNGS beam using the 2012 dedicated data

    CERN Document Server

    Adam, T.; Aleksandrov, A.; Anokhina, A.; Aoki, S.; Ariga, A.; Ariga, T.; Autiero, D.; Badertscher, A.; Dhahbi, A.Ben; Beretta, M.; Bertolin, A.; Bozza, C.; Brugiere, T.; Brugnera, R.; Brunet, F.; Brunetti, G.; Buettner, B.; Buontempo, S.; Carlus, B.; Cavanna, F.; Cazes, A.; Chaussard, L.; Chernyavsky, M.; Chiarella, V.; Chukanov, A.; D'Ambrosio, N.; De Lellis, G.; De Serio, M.; del Amo Sanchez, P.; Di Crescenzo, A.; Di Ferdinando, D.; Di Marco, N.; Dmitrievsky, S.; Dracos, M.; Duchesneau, D.; Dusini, S.; Dzhatdoev, T.; Ebert, J.; Ereditato, A.; Esposito, L.S.; Favier, J.; Felici, G.; Ferber, T.; Fini, R.A.; Fukuda, T.; Garfagnini, A.; Giacomelli, G.; Girerd, C.; Goellnitz, C.; Goldberg, J.; Golubkov, D.; Gornushkin, Y.; Grella, G.; Grianti, F.; Guerin, C.; Guler, A.M.; Gustavino, C.; Hagner, C.; Hamada, K.; Hara, T.; Hierholzer, M.; Hollnagel, A.; Ishida, H.; Ishiguro, K.; Jakovcic, K.; Jollet, C.; Kamiscioglu, C.; Kamiscioglu, M.; Kawada, J.; Kim, J.H.; Kim, S.H.; Kimura, M.; Kitagawa, N.; Klicek, B.; Kodama, K.; Komatsu, M.; Kose, U.; Kreslo, I.; Lauria, A.; Lazzaro, C.; Lenkeit, J.; Ljubicic, A.; Longhin, A.; Mancini-Terracciano, C.; Malgin, A.; Mandrioli, G.; Marteau, J.; Matsuo, T.; Matveev, V.; Mauri, N.; Medinaceli, E.; Meregaglia, A.; Migliozzi, P.; Mikado, S.; Monacelli, P.; Montesi, M.C.; Morishima, K.; Moser, U.; Muciaccia, M.T.; Nakamura, M.; Nakano, T.; Nakatsuka, Y.; Naumov, D.; Nikitina, V.; Ogawa, S.; Olchevsky, A.; Ozaki, K.; Palamara, O.; Paoloni, A.; Park, B.D.; Park, I.G.; Pastore, A.; Patrizii, L.; Pennacchio, E.; Pessard, H.; Pistillo, C.; Podgrudkov, D.; Polukhina, N.; Pozzato, M.; Pretzl, K.; Pupilli, F.; Rescigno, R.; Roda, M.; Roganova, T.; Rokujo, H.; Rosa, G.; Rostovtseva, I.; Rubbia, A.; Russo, A.; Ryazhskaya, O.; Sato, O.; Sato, Y.; Schembri, A.; Schmidt-Parzefall, W.; Schuler, J.; Shakiryanova, I.; Sheshukov, A.; Shibuya, H.; Shoziyoev, G.; Simone, S.; Sioli, M.; Sirignano, C.; Sirri, G.; Song, J.S.; Spinetti, M.; Stanco, L.; Starkov, N.; Stellacci, S.M.; Stipcevic, M.; Strauss, T.; Takahashi, S.; Tenti, M.; Terranova, F.; Tioukov, V.; Tolun, P.; Tufanli, S.; Vilain, P.; Vladimirov, M.; Votano, L.; Vuilleumier, J.L.; Wilquet, G.; Wonsak, B.; Wurtz, J.; Yoon, C.S.; Yoshida, J.; Zaitsev, Y.; Zemskova, S.; Zghiche, A.; Zimmermann, R.

    2013-01-01

    In spring 2012 CERN provided two weeks of a short bunch proton beam dedicated to the neutrino velocity measurement over a distance of 730 km. The OPERA neutrino experiment at the underground Gran Sasso Laboratory used an upgraded setup compared to the 2011 measurements, improving the measurement time accuracy. An independent timing system based on the Resistive Plate Chambers was exploited providing a time accuracy of $\\sim$1 ns. Neutrino and anti-neutrino contributions were separated using the information provided by the OPERA magnetic spectrometers. The new analysis profited from the precision geodesy measurements of the neutrino baseline and of the CNGS/LNGS clock synchronization. The neutrino arrival time with respect to the one computed assuming the speed of light in vacuum is found to be $\\delta t_\

  9. Children's at Home: Pilot Study Assessing Dedicated Social Media for Parents of Adolescents with Neurofibromatosis Type 1.

    Science.gov (United States)

    Akre, Christina; Polvinen, Julie; Ullrich, Nicole J; Rich, Michael

    2018-04-01

    The aim of this pilot study was to evaluate Children's at Home (C@H), a dedicated social media website for parents of adolescents with neurofibromatosis type 1 (NF1). The interventional study included two phases: (1) creating video intervention/prevention assessment (VIA) visual narratives about having an adolescent with NF1 and (2) interacting on C@H, a secure, medically moderated social media website. C@H was evaluated qualitatively at three time points. At enrollment (T0, N = 17), participants reported needing C@H to break their isolation, connect with other families, and receive accurate information, advice, and support from others facing similar challenges. At T1, after creating VIA during 6 months (N = 13, 145 videos), participants mostly valued the opportunity to speak about the challenges they face with NF1 and their journey since diagnosis. At T2, after interacting on C@H for 7 weeks (N = 10, two sign-ins/week/parent), participants reported connecting with other parents of children with NF1 for the first time, valuing the "real faces" and emotions of other parents with shared experiences providing a sense of normalcy. Qualitative analysis suggested that C@H decreased feelings of isolation, provided relief to talk about NF1 without having to explain it, provided new knowledge about NF1 and the opportunity to address non-medical issues of NF1 never discussed in clinic, and helped participants with putting their lives into perspective. C@H allowed parents of adolescents with NF1 to overcome previous isolation and connect for the first time. Innovative applications of social media dedicated to those who care for children with chronic conditions can provide peer-to-peer support, shared experience, and reliable medical information.

  10. A community call for a dedicated radiobiological research facility to support particle beam cancer therapy

    DEFF Research Database (Denmark)

    Holzscheiter, Michael H.; Bassler, Niels; Dosanjh, Manjit

    2012-01-01

    Recently more than one hundred researchers followed an invitation to a brainstorming meeting on the topic of a future dedicated radio-biological and radio-physical research center. 100 more joint the meeting via webcast. After a day of presentations and discussions it was clear, that an urgent need...

  11. Optimal routing in an automated storage/retrieval system with dedicated storage

    NARCIS (Netherlands)

    Berg, van den J.P.; Gademann, A.J.R.M.

    1999-01-01

    We address the sequencing of requests in an automated storage/retrieval system with dedicated storage. We consider the block sequencing approach, where a set of storage and retrieval requests is given beforehand and no new requests come in during operation. The objective for this static problem is

  12. THE USE OF DEDICATED PEPTIDE LIBRARIES PERMITS THE DISCOVERY OF HIGH-AFFINITY BINDING PEPTIDES

    NARCIS (Netherlands)

    DEKOSTER, HS; AMONS, R; BENCKHUIJSEN, WE; FEIJLBRIEF, M; SCHELLEKENS, GA; DRIJFHOUT, JW

    1995-01-01

    The motif for peptide binding to monoclonal antibody mAb A16, which is known to be directed against glycoprotein D of Herpes simplex virus type 1, was determined using two dedicated peptide libraries. As a starting point for this study we used an A-16 binding lead sequence, which had previously been

  13. Discrete Mathematics - Special Issue: Graph Theory - dedicated to Carsten Thomassen on his 60th birthday

    DEFF Research Database (Denmark)

    2011-01-01

    Carsten Thomassen belongs to the worlds's absolute top graph theorists, and to the world's top mathematicians in general. The special issue is a rather somewhat random collection of good papers in graph theory, by many different authors, dedicated to Carsten Thomassen on his 60th birthday. Guest ...

  14. BTEV: a dedicated B physics detector at the Fermilab Tevatron Collider

    International Nuclear Information System (INIS)

    Butler, J.N.

    1996-11-01

    The capabilities of future Dedicated Hadron Collider B Physics experiments are discussed and compared to experiments that will run in the next few years. The design for such an experiment at the Tevatron Collider is presented and an evolutionary path for developing it is outlined. 9 refs., 3 figs., 4 tabs

  15. Implications of dose limit modification for radioactive installations dedicated to research

    International Nuclear Information System (INIS)

    Lumbreras, J.M.; Fernandez, G.M.; Marana, D.

    1992-01-01

    The reduced dose limits proposed in the ICRP recommendations affect the Spanish Regulations on Sanitary Protection against Ionizing Radiation. Some implications of this for radioactive installations dedicated to research are pointed out. A very simple statistical study shows that dosimetric data might be used to adopt new criteria for classification of personnel, and even of working areas. (author)

  16. Improving Vision Awareness in Autism Services: Evaluation of a Dedicated Education Programme for Support Practitioners

    Science.gov (United States)

    Long, Joseph J.; Butchart, Maggie; Brown, Michael; Bain, Janice; McMillan, Anne; Karatzias, Thanos

    2018-01-01

    Background: The research reported here sought to evaluate whether a dedicated education programme in vision awareness improved the knowledge and skills of autism support practitioners in identifying visual impairment in autistic people with intellectual disabilities and providing better support to those individuals identified as visually impaired.…

  17. Equipment Qualification and Environment Establishment for COTS Dedication of Safety Grade PC

    International Nuclear Information System (INIS)

    Ahn, Kwang Chul; Bin, Chang Sun; Kwon, Yoon Kwang; Kang, Shin Woo; Koh, Sung Won; Shon, Eui Chan; Jang, Hyun Doo; Song, Il Sup; Lee, Hyun Noh

    2010-08-01

    Safety grade PCs are required for protection systems of SKN 3 and 4 nuclear power plant and subsequent plants. Commercial grade item (CGI) dedication should be carried out to utilize a commercial PC as a safety grade PC of nuclear power plants. This project is aimed to perform the equipment qualification of the commercial PC, and review and improve the quality system of the PC supplier. As a result of the EQ for the CGI dedication, selected military PCs have passed the environment test, the seismic test, and the EMI test required for the digital controllers of nuclear plants. In addition, a walk-through of the quality system of the PC supplier, ISO 9001, was carried out and the quality system was improved. History data for the PC was gathered. As the analysis of the history data showed that operating experience time of the PC is longer than the plant life time, the history data could be used as an evidence of acceptance. After dedicated according to the CGI dedication process, military rugged PCs could be used for safety grade PCs

  18. Commercial grade item (CGI) dedication of MDR relays for nuclear safety related applications

    Science.gov (United States)

    Das, Ranjit K.; Julka, Anil; Modi, Govind

    1994-08-01

    MDR relays manufactured by Potter & Brumfield (P&B) have been used in various safety related applications in commercial nuclear power plants. These include emergency safety features (ESF) actuation systems, emergency core cooling systems (ECCS) actuation, and reactor protection systems. The MDR relays manufactured prior to May 1990 showed signs of generic failure due to corrosion and outgassing of coil varnish. P&B has made design changes to correct these problems in relays manufactured after May 1990. However, P&B does not manufacture the relays under any 10CFR50 Appendix B quality assurance (QA) program. They manufacture the relays under their commercial QA program and supply these as commercial grade items. This necessitates CGI Dedication of these relays for use in nuclear-safety-related applications. This paper presents a CGI dedication program that has been used to dedicate the MDR relays manufactured after been used to dedicate the MDR relays manufactured after May 1990. The program is in compliance with current Nuclear Regulatory Commission (NRC) and Electric Power Research Institute (EPRI) guidelines and applicable industry standards; it specifies the critical characteristics of the relays, provides the tests and analysis required to verify the critical characteristics, the acceptance criteria for the test results, performs source verification to quality P&B for its control of the critical characteristics, and provides documentation. The program provides reasonable assurance that the new MDR relays will perform their intended safety functions.

  19. What About the Moorish Footman? : Portrait of a Dutch Nabob as a Dedicated Follower of Fashion

    NARCIS (Netherlands)

    Kuiper, Yme; Ilmakunnas, Johanna; Stobart, Jon

    2017-01-01

    Collecting porcelain, furniture, lacquer, ivory objects, statues and folding screens from the Far East became very popular in Europe in the course of the eighteenth century. The Dutch nabob Jan Albert Sichterman (1692-1764), who as VOC-director made a big career in Bengal, was a dedicated follower

  20. An efficient hybrid protection scheme with shared/dedicated backup paths on elastic optical networks

    Directory of Open Access Journals (Sweden)

    Nogbou G. Anoh

    2017-02-01

    Full Text Available Fast recovery and minimum utilization of resources are the two main criteria for determining the protection scheme quality. We address the problem of providing a hybrid protection approach on elastic optical networks under contiguity and continuity of available spectrum constraints. Two main hypotheses are used in this paper for backup paths computation. In the first case, it is assumed that backup paths resources are dedicated. In the second case, the assumption is that backup paths resources are available shared resources. The objective of the study is to minimize spectrum utilization to reduce blocking probability on a network. For this purpose, an efficient survivable Hybrid Protection Lightpath (HybPL algorithm is proposed for providing shared or dedicated backup path protection based on the efficient energy calculation and resource availability. Traditional First-Fit and Best-Fit schemes are employed to search and assign the available spectrum resources. The simulation results show that HybPL presents better performance in terms of blocking probability, compared with the Minimum Resources Utilization Dedicated Protection (MRU-DP algorithm which offers better performance than the Dedicated Protection (DP algorithm.

  1. A dedicated tool for analysing protection selectivity and back-up in large MV networks

    NARCIS (Netherlands)

    Rombouts, S. P.J.; Morren, J.

    2010-01-01

    Due to integration of distributed generation the operation of medium-voltage distribution networks is becoming more difficult. This paper describes a dedicated simulation tool that can be used to study the protection coordination in the network. One of the main advantages of the program is that it

  2. Genetic Modification in Dedicated Bioenergy Crops and Strategies for Gene Confinement

    Science.gov (United States)

    Genetic modification of dedicated bioenergy crops is in its infancy; however, there are numerous advantages to the use of these tools to improve crops used for biofuels. Potential improved traits through genetic engineering (GE) include herbicide resistance, pest, drought, cold and salt tolerance, l...

  3. Gene Flow in Genetically Engineered Perennial Grasses: Lessons for Modification of Dedicated Bioenergy Crops

    Science.gov (United States)

    Genetic modification of dedicated bioenergy crops, such as switchgrass, will play a major role in crop improvement for a wide range of beneficial traits specific to biofuels. One obstacle that arises regarding transgenic improvement of perennials used for biofuels is the propensity of these plants t...

  4. Status of the dedicated short-range communications technology and applications : report to Congress.

    Science.gov (United States)

    2015-07-01

    This report responds to a Congressional request for an assessment of the 5.9 Gigahertz (GHz) Dedicated Short Range : Communications (DSRC) in accordance with the requirements provided by Congress in the Moving Ahead for Progress in the : 21st Century...

  5. An Optimized Version of a New Absolute Linear Encoder Dedicated to Intelligent Transportation Systems

    DEFF Research Database (Denmark)

    Argeseanu, Alin; Ritchie, Ewen; Leban, Krisztina Monika

    2009-01-01

    made in the coding algorithm, in the ruler topology and in the dedicated software. The optimized ALE is a robust device able to work in industrial environment, with a high level of vibrations. By this reason it is ideal for the transport system control in automating manufacturing processes, intelligent...

  6. A mycotoxin-dedicated total diet study in the Netherlands in 2013

    NARCIS (Netherlands)

    Sprong, R.C.; Wit-Bos, de L.; Zeilmaker, M.J.; Alewijn, M.; Castenmiller, J.J.M.; Mengelers, M.J.B.

    2016-01-01

    A mycotoxin-dedicated total diet study (mTDS) allowing assessment of occurrence and dietary exposure to these substances was developed and carried out in the Netherlands in 2013. First, literature was searched to establish the occurrence profile of mycotoxins. Next, foods as consumed according to

  7. Detection of rheumatoid arthritis bone erosions by two different dedicated extremity MRI units and conventional radiography

    DEFF Research Database (Denmark)

    Duer-Jensen, A.; Vestergaard, A.; Dohn, U.M.

    2008-01-01

    Objectives: To compare the ability of two different dedicated extremity MRI (E-MRI) units and conventional radiography (CR) for identifying bone erosions in rheumatoid arthritis (RA) metacarpophalangeal (MCP) and wrist joints. Methods: CR and two MRI examinations (using 0.2 T Esaote Artoscan and 0...

  8. Detection of rheumatoid arthritis bone erosions by 2 different dedicated extremity MRI units and conventional radiography

    DEFF Research Database (Denmark)

    Duer, Anne; Vestergaard, Aage; Døhn, Uffe Møller

    2008-01-01

    OBJECTIVES: To compare the ability of 2 different dedicated extremity magnetic resonance imaging (E-MRI) units and conventional radiography (CR) for identifying bone erosions in rheumatoid arthritis (RA) metacarpophalangeal (MCP) and wrist joints. METHODS: CR and 2 MRI-examinations (on 0.2T Esaote...

  9. An arrhythmia classification algorithm using a dedicated wavelet adapted to different subjects.

    Science.gov (United States)

    Kim, Jinkwon; Min, Se Dong; Lee, Myoungho

    2011-06-27

    Numerous studies have been conducted regarding a heartbeat classification algorithm over the past several decades. However, many algorithms have also been studied to acquire robust performance, as biosignals have a large amount of variation among individuals. Various methods have been proposed to reduce the differences coming from personal characteristics, but these expand the differences caused by arrhythmia. In this paper, an arrhythmia classification algorithm using a dedicated wavelet adapted to individual subjects is proposed. We reduced the performance variation using dedicated wavelets, as in the ECG morphologies of the subjects. The proposed algorithm utilizes morphological filtering and a continuous wavelet transform with a dedicated wavelet. A principal component analysis and linear discriminant analysis were utilized to compress the morphological data transformed by the dedicated wavelets. An extreme learning machine was used as a classifier in the proposed algorithm. A performance evaluation was conducted with the MIT-BIH arrhythmia database. The results showed a high sensitivity of 97.51%, specificity of 85.07%, accuracy of 97.94%, and a positive predictive value of 97.26%. The proposed algorithm achieves better accuracy than other state-of-the-art algorithms with no intrasubject between the training and evaluation datasets. And it significantly reduces the amount of intervention needed by physicians.

  10. An arrhythmia classification algorithm using a dedicated wavelet adapted to different subjects

    Directory of Open Access Journals (Sweden)

    Min Se Dong

    2011-06-01

    Full Text Available Abstract Background Numerous studies have been conducted regarding a heartbeat classification algorithm over the past several decades. However, many algorithms have also been studied to acquire robust performance, as biosignals have a large amount of variation among individuals. Various methods have been proposed to reduce the differences coming from personal characteristics, but these expand the differences caused by arrhythmia. Methods In this paper, an arrhythmia classification algorithm using a dedicated wavelet adapted to individual subjects is proposed. We reduced the performance variation using dedicated wavelets, as in the ECG morphologies of the subjects. The proposed algorithm utilizes morphological filtering and a continuous wavelet transform with a dedicated wavelet. A principal component analysis and linear discriminant analysis were utilized to compress the morphological data transformed by the dedicated wavelets. An extreme learning machine was used as a classifier in the proposed algorithm. Results A performance evaluation was conducted with the MIT-BIH arrhythmia database. The results showed a high sensitivity of 97.51%, specificity of 85.07%, accuracy of 97.94%, and a positive predictive value of 97.26%. Conclusions The proposed algorithm achieves better accuracy than other state-of-the-art algorithms with no intrasubject between the training and evaluation datasets. And it significantly reduces the amount of intervention needed by physicians.

  11. Evaluation of Why the Air Force Dedicated Personnel Recovery Mission Should Remain with Air Combat Command

    Science.gov (United States)

    2016-03-01

    purpose, and thus are a waste of government funds in a tight budget environment.84 Col Hanover argued that these 28 attacks come from a complete... bread and butter for the dedicated PR community, the broader PR umbrella truly enables the crews to continually conduct joint operations. This has

  12. Commercial grade item (CGI) dedication of generators for nuclear safety related applications

    International Nuclear Information System (INIS)

    Das, R.K.; Hajos, L.G.

    1993-01-01

    The number of nuclear safety related equipment suppliers and the availability of spare and replacement parts designed specifically for nuclear safety related application are shrinking rapidly. These have made it necessary for utilities to apply commercial grade spare and replacement parts in nuclear safety related applications after implementing proper acceptance and dedication process to verify that such items conform with the requirements of their use in nuclear safety related application. The general guidelines for the commercial grade item (CGI) acceptance and dedication are provided in US Nuclear Regulatory Commission (NRC) Generic Letters and Electric Power Research Institute (EPRI) Report NP-5652, Guideline for the Utilization of Commercial Grade Items in Nuclear Safety Related Applications. This paper presents an application of these generic guidelines for procurement, acceptance, and dedication of a commercial grade generator for use as a standby generator at Salem Generating Station Units 1 and 2. The paper identifies the critical characteristics of the generator which once verified, will provide reasonable assurance that the generator will perform its intended safety function. The paper also delineates the method of verification of the critical characteristics through tests and provide acceptance criteria for the test results. The methodology presented in this paper may be used as specific guidelines for reliable and cost effective procurement and dedication of commercial grade generators for use as standby generators at nuclear power plants

  13. Local curvature analysis for classifying breast tumors: Preliminary analysis in dedicated breast CT

    International Nuclear Information System (INIS)

    Lee, Juhun; Nishikawa, Robert M.; Reiser, Ingrid; Boone, John M.; Lindfors, Karen K.

    2015-01-01

    Purpose: The purpose of this study is to measure the effectiveness of local curvature measures as novel image features for classifying breast tumors. Methods: A total of 119 breast lesions from 104 noncontrast dedicated breast computed tomography images of women were used in this study. Volumetric segmentation was done using a seed-based segmentation algorithm and then a triangulated surface was extracted from the resulting segmentation. Total, mean, and Gaussian curvatures were then computed. Normalized curvatures were used as classification features. In addition, traditional image features were also extracted and a forward feature selection scheme was used to select the optimal feature set. Logistic regression was used as a classifier and leave-one-out cross-validation was utilized to evaluate the classification performances of the features. The area under the receiver operating characteristic curve (AUC, area under curve) was used as a figure of merit. Results: Among curvature measures, the normalized total curvature (C_T) showed the best classification performance (AUC of 0.74), while the others showed no classification power individually. Five traditional image features (two shape, two margin, and one texture descriptors) were selected via the feature selection scheme and its resulting classifier achieved an AUC of 0.83. Among those five features, the radial gradient index (RGI), which is a margin descriptor, showed the best classification performance (AUC of 0.73). A classifier combining RGI and C_T yielded an AUC of 0.81, which showed similar performance (i.e., no statistically significant difference) to the classifier with the above five traditional image features. Additional comparisons in AUC values between classifiers using different combinations of traditional image features and C_T were conducted. The results showed that C_T was able to replace the other four image features for the classification task. Conclusions: The normalized curvature measure

  14. Specialist trainees on rotation cannot replace dedicated consultant clinicians for antimicrobial stewardship of specialty disciplines

    Directory of Open Access Journals (Sweden)

    Yeo Chay Leng

    2012-11-01

    Full Text Available Abstract Our prospective-audit-and-feedback antimicrobial stewardship (AS program for hematology and oncology inpatients was switched from one led by dedicated clinicians to a rotating team of infectious diseases trainees in order to provide learning opportunities and attempt a “de-escalation” of specialist input towards a more protocol-driven implementation. However, process indicators including the number of recommendations and recommendation acceptance rates fell significantly during the year, with accompanying increases in broad-spectrum antibiotic prescription. The trends were reversed only upon reverting to the original setup. Dedicated clinicians play a crucial role in AS programs involving immunocompromised patients. Structured training and adequate succession/contingency planning is critical for sustainability.

  15. The Integration of Disability Content into Social Work Education: An Examination of Infused and Dedicated Models

    Directory of Open Access Journals (Sweden)

    Kristen Faye Bean

    2012-09-01

    Full Text Available Disability content has been slowly integrated into social work curricula despite the large proportion of social workers supporting people with disabilities and its requirement in social work education by the Council on Social Work Education Educational Policy and Accreditation Standards. Schools of social work offer disability content to their students in three ways: infused, dedicated (specialization, or a combination of both. A content analysis of 1620 course titles and descriptions from the top schools of social work was conducted to assess the integration of disability content into social work curricula. Eighty percent of the schools included disability content in their curriculum. Disability content was more likely to be integrated using the infused rather than the dedicated model.

  16. Distributed computing feasibility in a non-dedicated homogeneous distributed system

    Science.gov (United States)

    Leutenegger, Scott T.; Sun, Xian-He

    1993-01-01

    The low cost and availability of clusters of workstations have lead researchers to re-explore distributed computing using independent workstations. This approach may provide better cost/performance than tightly coupled multiprocessors. In practice, this approach often utilizes wasted cycles to run parallel jobs. The feasibility of such a non-dedicated parallel processing environment assuming workstation processes have preemptive priority over parallel tasks is addressed. An analytical model is developed to predict parallel job response times. Our model provides insight into how significantly workstation owner interference degrades parallel program performance. A new term task ratio, which relates the parallel task demand to the mean service demand of nonparallel workstation processes, is introduced. It was proposed that task ratio is a useful metric for determining how large the demand of a parallel applications must be in order to make efficient use of a non-dedicated distributed system.

  17. Molecular Imaging in Breast Cancer: From Whole-Body PET/CT to Dedicated Breast PET

    Directory of Open Access Journals (Sweden)

    B. B. Koolen

    2012-01-01

    Full Text Available Positron emission tomography (PET, with or without integrated computed tomography (CT, using 18F-fluorodeoxyglucose (FDG is based on the principle of elevated glucose metabolism in malignant tumors, and its use in breast cancer patients is frequently being investigated. It has been shown useful for classification, staging, and response monitoring, both in primary and recurrent disease. However, because of the partial volume effect and limited resolution of most whole-body PET scanners, sensitivity for the visualization of small tumors is generally low. To improve the detection and quantification of primary breast tumors with FDG PET, several dedicated breast PET devices have been developed. In this nonsystematic review, we shortly summarize the value of whole-body PET/CT in breast cancer and provide an overview of currently available dedicated breast PETs.

  18. Use of a microprocessor in the CAMAC standard. The dedicated microcomputer: JCAM-10

    International Nuclear Information System (INIS)

    Gallice, Pierre.

    1978-01-01

    The general purpose minicomputers and dedicated crate controllers currently used in small CAMAC systems are now being superseded by autonomous crate controllers with built-in microprocessor such as the JCAM-10, which is in fact a CAMAC dedicated microcomputer. This controller has been designed around the INTEL-8080 microprocessor and employs a semiconductor memory. The very much reduced price and smaller packaging of this module, and the relatively large potential market of CAMAC systems justify the tremendous efforts required for the study of its complete system as well in hardware than in software. After a short description of the CAMAC standard this paper will describe the principle of the microcomputer JCAM-10, and its complementary system: hardware (peripheral modules) and software (TTY command processor, Input Output, Control system, interrupt system, text editor, local macro-assembler, LP and BASICAM local compilers). As application examples, an autonomous counting system and a distributed intelligence system will be described [fr

  19. Eddy Current Transducer Dedicated for Sigma Phase Evaluation in Duplex Stainless Steel

    Directory of Open Access Journals (Sweden)

    Grzegorz Psuj

    2012-01-01

    Full Text Available The paper describes a new transducer dedicated for evaluation of a duplex stainless steel (DSS. Different phases which exist in DSS have influence on mechanical as well as on electrical properties. Therefore, an eddy current transducer was utilized. In order to achieve high sensitivity, a differential type of the transducer was selected. The performance of the transducer was verified by utilizing the samples which had a different amount of sigma phase.

  20. The MAPLE-X concept dedicated to the production of radio-isotopes

    International Nuclear Information System (INIS)

    Heeds, W.

    1985-06-01

    MAPLE is a versatile new Canadian multi-purpose research reactor concept that meets the nuclear aspirations of developing countries. It is planned to convert the NRX reactor at Chalk River Nuclear Laboratories into MAPLE-X as a demonstration prototype of this concept and thereafter to dedicate its operation to the production of radio-isotopes. A description of MAPLE-X and details of molybdenum-99 production are given

  1. Time Management in the Operating Room: An Analysis of the Dedicated Minimally Invasive Surgery Suite

    Science.gov (United States)

    Hsiao, Kenneth C.; Machaidze, Zurab

    2004-01-01

    Background: Dedicated minimally invasive surgery suites are available that contain specialized equipment to facilitate endoscopic surgery. Laparoscopy performed in a general operating room is hampered by the multitude of additional equipment that must be transported into the room. The objective of this study was to compare the preparation times between procedures performed in traditional operating rooms versus dedicated minimally invasive surgery suites to see whether operating room efficiency is improved in the specialized room. Methods: The records of 50 patients who underwent laparoscopic procedures between September 2000 and April 2002 were retrospectively reviewed. Twenty-three patients underwent surgery in a general operating room and 18 patients in an minimally invasive surgery suite. Nine patients were excluded because of cystoscopic procedures undergone prior to laparoscopy. Various time points were recorded from which various time intervals were derived, such as preanesthesia time, anesthesia induction time, and total preparation time. A 2-tailed, unpaired Student t test was used for statistical analysis. Results: The mean preanesthesia time was significantly faster in the minimally invasive surgery suite (12.2 minutes) compared with that in the traditional operating room (17.8 minutes) (P=0.013). Mean anesthesia induction time in the minimally invasive surgery suite (47.5 minutes) was similar to time in the traditional operating room (45.7 minutes) (P=0.734). The average total preparation time for the minimally invasive surgery suite (59.6 minutes) was not significantly faster than that in the general operating room (63.5 minutes) (P=0.481). Conclusion: The amount of time that elapses between the patient entering the room and anesthesia induction is statically shorter in a dedicated minimally invasive surgery suite. Laparoscopic surgery is performed more efficiently in a dedicated minimally invasive surgery suite versus a traditional operating room. PMID

  2. Children’s interaction with the Internet: Time dedicated to communications and games

    OpenAIRE

    Molina, Jose Alberto; Campaña, Juan Carlos; Ortega, Raquel

    2016-01-01

    Assuming that families and educators should educate children with regard to the consumption and use of new technologies, and policy-makers will need to act accordingly to protect vulnerable children , we provide evidence of the time that children aged between 10 and 12 years old dedicate to two online activities: computer communication and computer gaming. To that end, we estimate a simultaneous SUR model with data from the Spanish Time Use Survey for 2009-2010. Results indicate that being fe...

  3. Berlin Electron Storage Ring BESSY: a dedicated XUV synchrotron radiation facility

    International Nuclear Information System (INIS)

    Muelhaupt, G.; Bradshaw, A.M.

    1985-01-01

    In response to national requirements in the fields of basic research, metrology and x-ray lithography it was decided in late 1977 to build a dedicated XUV synchrotron radiation source in Berlin. The history of the BESSY project, the user-oriented factors that determined the design parameters, the construction and commissioning of the facility as well as user operation and funding issues are reviewed

  4. A Novel Vaping Machine Dedicated to Fully Controlling the Generation of E-Cigarette Emissions

    OpenAIRE

    Soulet, Sébastien; Pairaud, Charly; Lalo, Hélène

    2017-01-01

    The accurate study of aerosol composition and nicotine release by electronic cigarettes is a major issue. In order to fully and correctly characterize aerosol, emission generation has to be completely mastered. This study describes an original vaping machine named Universal System for Analysis of Vaping (U-SAV), dedicated to vaping product study, enabling the control and real-time monitoring of applied flow rate and power. Repeatability and stability of the machine are demonstrated on flow ra...

  5. Supply of equipment and components, materials of dedicated commercial grade, other services

    International Nuclear Information System (INIS)

    Perdices, D.; Perez Medina, E.

    2014-01-01

    The following article describes the course of action of Tecnatom as Procurement Agent and Manufacturing Manager for the supply materials, equipment and components for the Spanish Nuclear Power Plants. We have devoted a special mention to the supply of dedicated commercial grade items (CGI), bringing together the services of Manufacturing Manager, Engineering service and testing facilities, simplifying the control of the supply chain with total warranty. (Author)

  6. Academic Outcome Measures of a Dedicated Education Unit Over Time: Help or Hinder?

    Science.gov (United States)

    Smyer, Tish; Gatlin, Tricia; Tan, Rhigel; Tejada, Marianne; Feng, Du

    2015-01-01

    Critical thinking, nursing process, quality and safety measures, and standardized RN exit examination scores were compared between students (n = 144) placed in a dedicated education unit (DEU) and those in a traditional clinical model. Standardized test scores showed that differences between the clinical groups were not statistically significant. This study shows that the DEU model is 1 approach to clinical education that can enhance students' academic outcomes.

  7. Dedicated Barrett's surveillance sessions managed by trained endoscopists improve dysplasia detection rate.

    Science.gov (United States)

    Ooi, Joanne; Wilson, Patrick; Walker, Giles; Blaker, Paul; DeMartino, Sabina; O'Donohue, John; Reffitt, David; Lanaspre, Effie; Chang, Fuju; Meenan, John; Dunn, Jason M

    2017-06-01

    Background and study aim  Barrett's esophagus (BE)-associated dysplasia is an important marker for risk of progression to esophageal adenocarcinoma (EAC) and an indication for endoscopic therapy. However, BE surveillance technique is variable. The aim of this study was to assess the effect of dedicated BE surveillance lists on dysplasia detection rate (DDR). Patients and methods  This was a prospective study of patients undergoing BE surveillance at two hospitals - community (UHL) and upper gastrointestinal center (GSTT). Four endoscopists (Group A) were trained in Prague classification, Seattle protocol biopsy technique, and lesion detection prior to performing BE surveillance endoscopies at both sites, with dedicated time slots or lists. The DDR was then compared with historical data from 47 different endoscopists at GSTT and 24 at UHL (Group B) who had undertaken Barrett's surveillance over the preceding 5-year period. Results  A total of 729 patients with BE underwent surveillance endoscopy between 2007 and 2012. There was no significant difference in patient age, sex, or length of BE between the two groups. There was a significant difference in detection rate of confirmed indefinite or low grade dysplasia and high grade dysplasia (HGD)/EAC between the two groups: 18 % (26 /142) Group A vs. 8 % (45/587) in Group B ( P  < 0.001). Documentation of Prague criteria and adherence to the Seattle protocol was significantly higher in Group A. Conclusion  This study demonstrated that a group of trained endoscopists undertaking Barrett's surveillance on dedicated lists had significantly higher DDR than a nonspecialist cohort. These findings support the introduction of dedicated Barrett's surveillance lists. © Georg Thieme Verlag KG Stuttgart · New York.

  8. Benefits of a Dedicated Breastfeeding Facility and Support Program for Exclusive Breastfeeding among Workers in Indonesia.

    Science.gov (United States)

    Basrowi, Ray W; Sulistomo, Astrid B; Adi, Nuri Purwito; Vandenplas, Yvan

    2015-06-01

    A mother's working environment is believed to be a major determinant of exclusive breastfeeding (EBF) practice. We aimed to define the influence of a facility dedicated to breastfeeding and a breastfeeding support program at the workplace on breastfeeding practice. A cross-sectional study was performed in five workplaces. The inclusion criteria were female workers whose last child was between 6 and 36 months old. Observational data were obtained and a questionnaire was filled out. The World Health Organization definition for EBF was used. Data from 186 subjects (74 office workers and 112 factory workers) were collected. Just over half (52%) of the mothers were between 20 and 46 years old, 75.3% had graduated from high school and university, 12.9% had more than two children and 36.0% owned a house. The prevalence of EBF during the last 6 months was 32.3%. A proper dedicated breastfeeding facility was available for 21.5% of the mothers, but only 7.5% had been in contact with a breastfeeding support program. The presence of a dedicated breastfeeding facility increased EBF practice almost threefold, by an odds ratio (OR) of 2.74 and a 95% confidence interval (CI) of 1.34-5.64 (pdedicated breastfeeding facility at the workplace as these simple measures significantly increase EBF.

  9. Minor actinide burning in dedicated lead-bismuth cooled fast reactors

    International Nuclear Information System (INIS)

    Hejzlar, P.; Driscoll, M.J.; Kazimi, M.S.; Todreas, N.E.

    2001-01-01

    The destruction of minor actinides (MA) in dedicated burners is of contemporary interest in Europe and Japan because it requires the deployment of smaller number of special transmutation facilities. A major fraction of Pu from spent LWR fuel can be then burned in PWRs (or fast reactors) using dedicated fertile-free fuel assemblies. However, the design of MA burning fast spectrum cores poses significant challenges because of deterioration of key safety parameters, in particular of the coolant void coefficient. This study proposes the concept of an lead-bismuth eutectic (LBE)-cooled dedicated MA burner having metallic fuel (MA-Pu-Zr) and streaming assemblies to attain acceptable coolant void worth performance. It is shown that a large 1800 MWth fertile-free core containing 37 wt% TRU with very high fraction of MA(59 wt%) from LWR spent fuel can be burned in a first cycle for 700 EFPDs with a very small reactivity swing: less than β eff . Moreover, the reactivity void worth is negative for a fully voided core when all surrounding coolant is kept at reference density. However, the core reactivity increases as coolant density falls from the reference value of 10.25 to 6 g/cm 3 . Because its coolant density coefficient value is less than that of a sodium cooled IFR, the concept provides good potential for the achievement of self-regulation characteristics in unprotected events, provided that small negative fuel temperature feedback can be maintained. (authors)

  10. Investigation of a novel image segmentation method dedicated to forest fire applications

    Science.gov (United States)

    Rudz, S.; Chetehouna, K.; Hafiane, A.; Laurent, H.; Séro-Guillaume, O.

    2013-07-01

    To face fire it is crucial to understand its behaviour in order to maximize fighting means. To achieve this task, the development of a metrological tool is necessary for estimating both geometrical and physical parameters involved in forest fire modelling. A key parameter is to estimate fire positions accurately. In this paper an image processing tool especially dedicated to an accurate extraction of fire from an image is presented. In this work, the clustering on several colour spaces is investigated and it appears that the blue chrominance Cb from the YCbCr colour space is the most appropriate. As a consequence, a new segmentation algorithm dedicated to forest fire applications has been built using first an optimized k-means clustering in the Cb-channel and then some properties of fire pixels in the RGB colour space. Next, the performance of the proposed method is evaluated using three supervised evaluation criteria and then compared to other existing segmentation algorithms in the literature. Finally a conclusion is drawn, assessing the good behaviour of the developed algorithm. This paper is dedicated to the memory of Dr Olivier Séro-Guillaume (1950-2013), CNRS Research Director.

  11. Impact of dedicated E85 vehicle use on ozone and particulate matter in the US

    Science.gov (United States)

    Nopmongcol, Uarporn; Griffin, W. Michael; Yarwood, Greg; Dunker, Alan M.; MacLean, Heather L.; Mansell, Gerard; Grant, John

    2011-12-01

    Increased use of ethanol as a vehicle fuel worldwide warrants the need to understand air quality impacts of replacing gasoline with ethanol. This study evaluates the impacts of dedicated E85 (85% ethanol/15% gasoline) light-duty vehicles on emissions, ozone and particulate matter (PM) concentrations in the United States for a future year (2022) using a 3-D photochemical model, detailed emissions inventories that account for changes in all sectors studied, and winter and summer meteorology that occurred in 2002. Use of E85 introduces new emissions from ethanol production and distribution, reduces petrochemical industry emissions due to lower gasoline consumption, changes on-road vehicle emissions and alters biogenic emissions due to land use changes. Three scenarios with increased ethanol production for dedicated E85 light-duty vehicles were compared to a base case without increased ethanol production. Increased use of E85 caused both increases and decreases in ozone and PM, driven mainly by changes in NO x emissions related to biogenic and upstream petrochemical industry sources. In all states modeled, adoption of dedicated E85 vehicles caused negligible change in average higher ozone and PM concentrations of importance for air quality management strategies. Ozone and PM changes are relatively insensitive to how land area is allocated for switchgrass production. The findings are subject to various uncertainties, especially those in vehicle technology and emissions from cellulosic ethanol production.

  12. Dental MRI using a dedicated RF-coil at 3 Tesla.

    Science.gov (United States)

    Prager, Marcel; Heiland, Sabine; Gareis, Daniel; Hilgenfeld, Tim; Bendszus, Martin; Gaudino, Chiara

    2015-12-01

    To assess the benefit of a dedicated surface coil to visualize dental structures in comparison to standard head/neck coil. Measurements were performed using the standard head/neck coil and a dedicated array coil for dental MRI at 3 T. As MRI methods, we used a T1-weighted spin-echo sequence with and without spectral fat saturation, a T2-weighted turbo-spin-echo sequence and a 3-dimensional T2-weighted SPACE sequence. Measurements were performed in a phantom to examine sensitivity profiles. Then the signal gain in dental structures was examined in volunteers and in a patient. As expected for a surface coil, the signal gain of the dental coil was highest at the surface of the phantom and decreased with increasing distance to the coil; it was >120% even at a depth of 30 mm, measured from the centre of the coil. The signal gain within the pulp of the volunteers ranged between 236 and 413%. The dedicated array coil offers a significantly higher signal within the region of interest for dental MR imaging thus allowing for better depiction of pathologies within the periodontium and for delineation and tracking of the branches of the maxillary and mandibular nerves. Copyright © 2015 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

  13. Interactive dedicated training curriculum improves accuracy in the interpretation of MR imaging of prostate cancer

    International Nuclear Information System (INIS)

    Akin, Oguz; Zhang, Jingbo; Hricak, Hedvig; Riedl, Christopher C.; Ishill, Nicole M.; Moskowitz, Chaya S.

    2010-01-01

    To assess the effect of interactive dedicated training on radiology fellows' accuracy in assessing prostate cancer on MRI. Eleven radiology fellows, blinded to clinical and pathological data, independently interpreted preoperative prostate MRI studies, scoring the likelihood of tumour in the peripheral and transition zones and extracapsular extension. Each fellow interpreted 15 studies before dedicated training (to supply baseline interpretation accuracy) and 200 studies (10/week) after attending didactic lectures. Expert radiologists led weekly interactive tutorials comparing fellows' interpretations to pathological tumour maps. To assess interpretation accuracy, receiver operating characteristic (ROC) analysis was conducted, using pathological findings as the reference standard. In identifying peripheral zone tumour, fellows' average area under the ROC curve (AUC) increased from 0.52 to 0.66 (after didactic lectures; p < 0.0001) and remained at 0.66 (end of training; p < 0.0001); in the transition zone, their average AUC increased from 0.49 to 0.64 (after didactic lectures; p = 0.01) and to 0.68 (end of training; p = 0.001). In detecting extracapsular extension, their average AUC increased from 0.50 to 0.67 (after didactic lectures; p = 0.003) and to 0.81 (end of training; p < 0.0001). Interactive dedicated training significantly improved accuracy in tumour localization and especially in detecting extracapsular extension on prostate MRI. (orig.)

  14. Interactive dedicated training curriculum improves accuracy in the interpretation of MR imaging of prostate cancer

    Energy Technology Data Exchange (ETDEWEB)

    Akin, Oguz; Zhang, Jingbo; Hricak, Hedvig [Memorial Sloan-Kettering Cancer Center, Department of Radiology, New York, NY (United States); Riedl, Christopher C. [Memorial Sloan-Kettering Cancer Center, Department of Radiology, New York, NY (United States); Medical University of Vienna, Department of Radiology, Vienna (Austria); Ishill, Nicole M.; Moskowitz, Chaya S. [Memorial Sloan-Kettering Cancer Center, Epidemiology and Biostatistics, New York, NY (United States)

    2010-04-15

    To assess the effect of interactive dedicated training on radiology fellows' accuracy in assessing prostate cancer on MRI. Eleven radiology fellows, blinded to clinical and pathological data, independently interpreted preoperative prostate MRI studies, scoring the likelihood of tumour in the peripheral and transition zones and extracapsular extension. Each fellow interpreted 15 studies before dedicated training (to supply baseline interpretation accuracy) and 200 studies (10/week) after attending didactic lectures. Expert radiologists led weekly interactive tutorials comparing fellows' interpretations to pathological tumour maps. To assess interpretation accuracy, receiver operating characteristic (ROC) analysis was conducted, using pathological findings as the reference standard. In identifying peripheral zone tumour, fellows' average area under the ROC curve (AUC) increased from 0.52 to 0.66 (after didactic lectures; p < 0.0001) and remained at 0.66 (end of training; p < 0.0001); in the transition zone, their average AUC increased from 0.49 to 0.64 (after didactic lectures; p = 0.01) and to 0.68 (end of training; p = 0.001). In detecting extracapsular extension, their average AUC increased from 0.50 to 0.67 (after didactic lectures; p = 0.003) and to 0.81 (end of training; p < 0.0001). Interactive dedicated training significantly improved accuracy in tumour localization and especially in detecting extracapsular extension on prostate MRI. (orig.)

  15. 33 CFR Appendix D to Part 157 - Example of a Procedure for Dedicated Clean Ballast Tanks Operations

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Example of a Procedure for... ENVIRONMENT RELATING TO TANK VESSELS CARRYING OIL IN BULK Pt. 157, App. D Appendix D to Part 157—Example of a Procedure for Dedicated Clean Ballast Tanks Operations 1. Source. The example procedure for dedicated clean...

  16. Are the most dedicated nurses more vulnerable to job insecurity? Age-specific analyses on family-related outcomes.

    Science.gov (United States)

    Ruokolainen, Mervi; Mauno, Saija; Cheng, Ting

    2014-11-01

    To examine the moderating roles of job dedication and age in the job insecurity-family-related well-being relationship. As job insecurity is a rather permanent stressor among nurses nowadays, more research is needed on the buffering factors alleviating its negative effects on well-being. A total of 1719 Finnish nurses representing numerous health care organisations participated in this cross-sectional study. Moderated hierarchical regression analysis was used to examine the associations. Nurses' younger age and low job dedication operated as protective factors against the negative effect of high job insecurity on parental satisfaction. The effect of job dedication on family-related well-being was also age-specific: high job dedication protected younger nurses from the negative effect of job insecurity on work-family conflict and parental stress, whereas among older nurses those who reported low job dedication showed better well-being in the presence of high job insecurity. The most job-dedicated nurses were more vulnerable to job insecurity in relation to parental satisfaction. In addition, high job dedication combined with high age implied more work-family conflict and parental stress in the presence of high job insecurity. Managers should seek to boost younger nurses' job dedication and to prevent older nurses' over-commitment. © 2013 John Wiley & Sons Ltd.

  17. Health Information Systems.

    Science.gov (United States)

    Sirintrapun, S Joseph; Artz, David R

    2015-06-01

    This article provides surgical pathologists an overview of health information systems (HISs): what they are, what they do, and how such systems relate to the practice of surgical pathology. Much of this article is dedicated to the electronic medical record. Information, in how it is captured, transmitted, and conveyed, drives the effectiveness of such electronic medical record functionalities. So critical is information from pathology in integrated clinical care that surgical pathologists are becoming gatekeepers of not only tissue but also information. Better understanding of HISs can empower surgical pathologists to become stakeholders who have an impact on the future direction of quality integrated clinical care. Copyright © 2015 Elsevier Inc. All rights reserved.

  18. Proceedings of Republic conference (with participation of scientists from Commonwealth of Independent States countries) 'Modern problems of semiconductor physics', dedicated for twentieth anniversary of independence of Republic Uzbekistan

    International Nuclear Information System (INIS)

    Matchanov, A.T.; Tagaev, M.B.; Ismaylov, K.A.

    2011-11-01

    Republic conference with participation of scientists from Commonwealth of Independent States countries 'Modern problems of semiconductor physics', dedicated for twentieth anniversary of independence of Republic Uzbekistan was held on 23-25 November, 2011 in Nukus, Uzbekistan. Specialists and young scientists from universities and academic research institutes discussed various aspects of modern problems of semiconductor physics. More than 100 talks were presented in the meeting on the following subjects: solid state physics, physics of condensed matter and nano materials; educational tools and information technologies. (K.M.)

  19. CURIE: a new clear air doppler radar dedicated to the lower part of the atmospheric boundary layer (20 m- 750m)

    International Nuclear Information System (INIS)

    Al-Sakka, H; Weill, A; Gac, C Le; Ney, R; Dupont, E

    2008-01-01

    A new X-band miniradar, the CURIE radar (Canopy Urban Research on Interactions and Exchanges), mainly adapted to low Atmospheric Boundary Layer sounding has been developed at CETP. After a brief description of the opportunity and working conditions in a turbulent atmosphere, main characteristics are presented. Though this radar works in presence of precipitation as all X-band radar can do, this paper is more dedicated to clear air used in the turbulent atmospheric boundary layer. We are presented comparisons with UHF observations and boundary layer information which can be inferred from CURIE as entrainment across the inversion layer

  20. Homogenised constitutive model dedicated to reinforced concrete plates subjected to seismic solicitations

    International Nuclear Information System (INIS)

    Combescure, Christelle

    2013-01-01

    Safety reassessments are periodically performed on the EDF nuclear power plants and the recent seismic reassessments leaded to the necessity of taking into account the non-linear behaviour of materials when modeling and simulating industrial structures of these power plants under seismic solicitations. A large proportion of these infrastructures is composed of reinforced concrete buildings, including reinforced concrete slabs and walls, and literature seems to be poor on plate modeling dedicated to seismic applications for this material. As for the few existing models dedicated to these specific applications, they present either a lack of dissipation energy in the material behaviour, or no micromechanical approach that justifies the parameters needed to properly describe the model. In order to provide a constitutive model which better represents the reinforced concrete plate behaviour under seismic loadings and whose parameters are easier to identify for the civil engineer, a constitutive model dedicated to reinforced concrete plates under seismic solicitations is proposed: the DHRC (Dissipative Homogenised Reinforced Concrete) model. Justified by a periodic homogenisation approach, this model includes two dissipative phenomena: damage of concrete matrix and internal sliding at the interface between steel rebar and surrounding concrete. An original coupling term between damage and sliding, resulting from the homogenisation process, induces a better representation of energy dissipation during the material degradation. The model parameters are identified from the geometric characteristics of the plate and a restricted number of material characteristics, allowing a very simple use of the model. Numerical validations of the DHRC model are presented, showing good agreement with experimental behaviour. A one dimensional simplification of the DHRC model is proposed, allowing the representation of reinforced concrete bars and simplified models of rods and wire mesh

  1. [Major influential factors of the micturition alert device dedicated to neurogenic bladders].

    Science.gov (United States)

    Wang, Jianhuo; Hou, Chunlin; Zheng, Xianyou; Xu, Zhen; Wang, Wanhong; Lin, Haodong

    2008-08-01

    To study major influential factors of the micturition alert device dedicated to neurogenic bladders for the product design and clinical application of the device. One ferrite permanent magnet with thickness and diameter of 3 mm and 10 mm, respectively, and three NdFeB permanent magnets with the thickness of 3 mm and diameter of 10, 15 and 20 mm, respectively, were used. The effects of thickness of the abdominal wall as well as the position and type of permanent magnets on the micturition alert device dedicated to neurogenic bladders were measured in vitro simulated test, when the abdominal wall was set to 2, 3, 4, 5, 6, 7, 8 and 9 cm, respectively, and the position of permanent magnets was 0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 and 12 cm, respectively. The effect of the geomagnetic field on the device was measured under the condition that the thickness of the simulated abdominal wall was set to 2, 3, 4 and 5 cm, respectively, and the position of permanent magnets was 2, 3, 4, 5, 6, 7, 8, 9 and 10 cm, respectively. The value showed in the warning unit was positively correlated with the position of the ferrite permanent magnet only when the thickness of the simulated abdominal wall was 2 cm (r=0.632, P NdFeB permanent magnets was significant (r > 0.622, P NdFeB permanent magnets, but weakened with the increasing thickness of the simulated abdominal wall. The effect of the geomagnetic field was correlated with the exposition of the body, the position of the permanent magnet and the thickness of the abdominal wall. The major influential factors of the micturition alert device dedicated to neurogenic bladder include the magnetism and location of the permanent magnet, the thickness of the abdominal wall and the geomagnetic field. These factors are correlated with and affect each other. Reasonable allocation of these factors may optimize the device.

  2. Short-term outcomes following implementation of a dedicated young adult congenital heart disease transition program.

    Science.gov (United States)

    Vaikunth, Sumeet S; Williams, Roberta G; Uzunyan, Merujan Y; Tun, Han; Barton, Cheryl; Chang, Philip M

    2018-01-01

    Transition from pediatric to adult care is a critical time for patients with congenital heart disease. Lapses in care can lead to poor outcomes, including increased mortality. Formal transition clinics have been implemented to improve success of transferring care from pediatric to adult providers; however, data regarding outcomes remain limited. We sought to evaluate outcomes of transfer within a dedicated transition clinic for young adult patients with congenital heart disease. We performed a retrospective analysis of all 73 patients seen in a dedicated young adult congenital heart disease transition clinic from January 2012 to December 2015 within a single academic institution that delivered pediatric and adult care at separate children's and adult hospitals, respectively. Demographic characteristics including congenital heart disease severity, gender, age, presence of comorbidities, presence of cardiac implantable electronic devices, and type of insurance were correlated to success of transfer. Rate of successful transfer was evaluated, and multivariate analysis was performed to determine which demographic variables were favorably associated with transfer. Thirty-nine percent of patients successfully transferred from pediatric to adult services during the study period. Severe congenital heart disease (OR 4.44, 95% CI 1.25-15.79, P = .02) and presence of a cardiac implantable electronic device (OR 4.93, 95% CI 1.18-20.58, P = .03) correlated with transfer. Trends favoring successful transfer with presence of comorbidities and private insurance were also noted. Despite a dedicated transition clinic, successful transfer rates remained relatively low though comparable to previously published rates. Severity of disease and presence of implantable devices correlated with successful transfer. Other obstacles to transfer remain and require combined efforts from pediatric and adult care systems, insurance carriers, and policy makers to improve transfer outcomes.

  3. Reengineering GSM/GPRS Towards a Dedicated Network for Massive Smart Metering

    DEFF Research Database (Denmark)

    Madueño, Germán Corrales; Stefanovic, Cedomir; Popovski, Petar

    2014-01-01

    GSM is a synonym for a major success in wireless technology, achieving widespread use and high technology maturity. However, its future is questionable, as many stakeholders indicate that the GSM spectrum should be re-farmed for LTE. On the other hand, the advent of smart grid and the ubiquity...... of smart meters will require reliable, long-lived wide area connections. This motivates to investigate the potential of GSM to be evolved into a dedicated network for smart metering. We introduce simple mechanisms to reengineer the access control in GSM. The result is a system that offers excellent support...

  4. A dedicated breast-PET/CT scanner: Evaluation of basic performance characteristics.

    Science.gov (United States)

    Raylman, Raymond R; Van Kampen, Will; Stolin, Alexander V; Gong, Wenbo; Jaliparthi, Gangadhar; Martone, Peter F; Smith, Mark F; Sarment, David; Clinthorne, Neal H; Perna, Mark

    2018-04-01

    Application of advanced imaging techniques, such as PET and x ray CT, can potentially improve detection of breast cancer. Unfortunately, both modalities have challenges in the detection of some lesions. The combination of the two techniques, however, could potentially lead to an overall improvement in diagnostic breast imaging. The purpose of this investigation is to test the basic performance of a new dedicated breast-PET/CT. The PET component consists of a rotating pair of detectors. Its performance was evaluated using the NEMA NU4-2008 protocols. The CT component utilizes a pulsed x ray source and flat panel detector mounted on the same gantry as the PET scanner. Its performance was assessed using specialized phantoms. The radiation dose to a breast during CT imaging was explored by the measurement of free-in-air kerma and air kerma measured at the center of a 16 cm-diameter PMMA cylinder. Finally, the combined capabilities of the system were demonstrated by imaging of a micro-hot-rod phantom. Overall, performance of the PET component is comparable to many pre-clinical and other dedicated breast-PET scanners. Its spatial resolution is 2.2 mm, 5 mm from the center of the scanner using images created with the single-sliced-filtered-backprojection algorithm. Peak NECR is 24.6 kcps; peak sensitivity is 1.36%; the scatter fraction is 27%. Spatial resolution of the CT scanner is 1.1 lp/mm at 10% MTF. The free-in-air kerma is 2.33 mGy, while the PMMA-air kerma is 1.24 mGy. Finally, combined imaging of a micro-hot-rod phantom illustrated the potential utility of the dual-modality images produced by the system. The basic performance characteristics of a new dedicated breast-PET/CT scanner are good, demonstrating that its performance is similar to current dedicated PET and CT scanners. The potential value of this system is the capability to produce combined duality-modality images that could improve detection of breast disease. The next stage in development of this system

  5. Coherent detection passive optical access network enabling converged delivery of broadcast and dedicated broadband services

    DEFF Research Database (Denmark)

    Osadchiy, Alexey Vladimirovich; Prince, Kamau; Guerrero Gonzalez, Neil

    2011-01-01

    We propose a passive optical network architecture based on coherent detection for converged delivery of broadcast services from a dedicated remote broadcast server and user-specific services from a local central office. We experimentally demonstrate this architecture with mixed traffic types....... The broadcast channels were transmitted over 78 km of single mode fiber to a central office where they were multiplexed with the unicast channels for further fiber transmission over 34-km to reach the access network. Successful detection of all channels is demonstrated....

  6. Clear-PEM: A PET imaging system dedicated to breast cancer diagnostics

    CERN Document Server

    Abreu, M C; Albuquerque, E; Almeida, F G; Almeida, P; Amaral, P; Auffray, Etiennette; Bento, P; Bruyndonckx, P; Bugalho, R; Carriço, B; Cordeiro, H; Ferreira, M; Ferreira, N C; Gonçalves, F; Lecoq, Paul; Leong, C; Lopes, F; Lousã, P; Luyten, J; Martins, M V; Matela, N; Rato-Mendes, P; Moura, R; Nobre, J; Oliveira, N; Ortigão, C; Peralta, L; Rego, J; Ribeiro, R; Rodrigues, P; Santos, A I; Silva, J C; Silva, M M; Tavernier, Stefaan; Teixeira, I C; Texeira, J P; Trindade, A; Trummer, Julia; Varela, J

    2007-01-01

    The Clear-PEM scanner for positron emission mammography under development is described. The detector is based on pixelized LYSO crystals optically coupled to avalanche photodiodes and readout by a fast low-noise electronic system. A dedicated digital trigger (TGR) and data acquisition (DAQ) system is used for on-line selection of coincidence events with high efficiency, large bandwidth and small dead-time. A specialized gantry allows to perform exams of the breast and of the axilla. In this paper we present results of the measurement of detector modules that integrate the system under construction as well as the imaging performance estimated from Monte Carlo simulated data.

  7. Demonstration of the importance of a dedicated neutron beam monitoring system for BNCT facility

    International Nuclear Information System (INIS)

    Chao, Der-Sheng; Liu, Yuan-Hao; Jiang, Shiang-Huei

    2016-01-01

    The neutron beam monitoring system is indispensable to BNCT facility in order to achieve an accurate patient dose delivery. The neutron beam monitoring of a reactor-based BNCT (RB-BNCT) facility can be implemented through the instrumentation and control system of a reactor provided that the reactor power level remains constant during reactor operation. However, since the neutron flux in reactor core is highly correlative to complicated reactor kinetics resulting from such as fuel depletion, poison production, and control blade movement, some extent of variation may occur in the spatial distribution of neutron flux in reactor core. Therefore, a dedicated neutron beam monitoring system is needed to be installed in the vicinity of the beam path close to the beam exit of the RB-BNCT facility, where it can measure the BNCT beam intensity as closely as possible and be free from the influence of the objects present around the beam exit. In this study, in order to demonstrate the importance of a dedicated BNCT neutron beam monitoring system, the signals originating from the two in-core neutron detectors installed at THOR were extracted and compared with the three dedicated neutron beam monitors of the THOR BNCT facility. The correlation of the readings between the in-core neutron detectors and the BNCT neutron beam monitors was established to evaluate the improvable quality of the beam intensity measurement inferred by the in-core neutron detectors. In 29 sampled intervals within 16 days of measurement, the fluctuations in the mean value of the normalized ratios between readings of the three BNCT neutron beam monitors lay within 0.2%. However, the normalized ratios of readings of the two in-core neutron detectors to one of the BNCT neutron beam monitors show great fluctuations of 5.9% and 17.5%, respectively. - Highlights: • Two in-core neutron detectors and three BNCT neutron beam monitors were compared. • BNCT neutron beam monitors improve the stability in neutron

  8. Transformation of colour space dedicated to an experimental analysis fulfilling the applicability criteria

    International Nuclear Information System (INIS)

    Ziemba, A; Fornalik-Wajs, E

    2014-01-01

    The choice of colour space is very important in the digital image analysis by reason of accuracy and computational time. Particle Image Velocimetry and Particle Image Thermometry are the optical methods commonly applied in the fluid dynamics and heat transfer. Especially in PIT method, the analysis of colour images is significant. In this paper, transformation of RGB to HSI colour space dedicated to PIT will be presented. Derivation of formulas together with its graphical representation will be discussed. Fulfilment of applicability criteria will be shown. This theoretical approach to digital image processing supplements the knowledge about the optical experimental methods.

  9. Development of dedicated nuclear heating plants in the Federal Republic of Germany

    International Nuclear Information System (INIS)

    Goetzmann, C.A.; Schroeter, K.E.

    1987-01-01

    In many cases district heating is both economically and environmentally superior over directly burning of fossil fuels in individual furnaces primarily because of the efficiency of the usual applied co-generation principle with regard to fuel utilization and flue gas clean up. In principle, this argument should carry even greater weight in conjunction with nuclear energy. The major draw back of dedicated heating reactors as seen up to now concerns the high specific capital cost for the application-dictated small reactor size. The paper discusses by way of a specific example in what directions solutions are being sought. (author)

  10. Dedicated Carrier Deployment in Heterogeneous Networks with Inter-site Carrier Aggregation

    DEFF Research Database (Denmark)

    Wang, Hua; Rosa, Claudio; Pedersen, Klaus I.

    2013-01-01

    the macrocell or the picocell using simple cell range expansion (RE). Extensive system-level simulations have been conducted to investigate the performance gains that can be achieved with inter-site CA under different traffic models and user distributions. Results show that using inter-site CA between......) or picos with dedicated carrier deployment. Collaborative inter-site carrier aggregation (CA) is proposed in scenarios with macro+RRH deployment to make an efficient use of the fragmented spectrum from multiple cells. While in scenarios with macro+pico deployment, UEs can only connect to either...

  11. Clinical peer mentoring: partnering BSN seniors and sophomores on a dedicated education unit.

    Science.gov (United States)

    Harmer, Bonnie McKay; Huffman, Jaime; Johnson, Barbara

    2011-01-01

    The authors describe a clinical peer mentoring (CPM) program that partnered 16 pairs of senior (mentors) and sophomore (novices) BSN students to provide patient care on a dedicated education unit at a VA Medical Center. Situated learning theory and Tanner's Clinical Judgment Model provided frameworks for CPM implementation. Survey findings suggested novices and mentors perceived improvements in self-confidence, prioritization, time management, clinical judgment, and evidence-based practice use. Many mentors spontaneously expressed an interest in becoming a preceptor or nurse educator. Copyright © 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins

  12. NucLab Marcoule. A laboratory facility dedicated to support dismantling operations

    International Nuclear Information System (INIS)

    Dugne, O.; Houssin, A.; Pierre, D.; Bec-Espitalier, L.

    2013-06-01

    Formerly dedicated to plutonium production support, NucLab was renovated to perform a wide range of analyses for dismantling, plant operation and process development activities mainly on Marcoule site but also outside (Veurey, Fontenay aux Roses). The Laboratory is under a CEA AREVA partnership as a CEA entity operated by AREVA employees. It provides services to several industrial operators (nuclear process and power plant) in the fields of analytical chemistry, radioactivity measurements, in situ nuclear measurements, decontamination processes and industrial chemistry processes, waste treatments to meet the following analysis requirements. NucLab today is able to support research, production and dismantling activities in all part of dismantling operations. (authors)

  13. The coming of age of the first hybrid metrology software platform dedicated to nanotechnologies (Conference Presentation)

    Science.gov (United States)

    Foucher, Johann; Labrosse, Aurelien; Dervillé, Alexandre; Zimmermann, Yann; Bernard, Guilhem; Martinez, Sergio; Grönqvist, Hanna; Baderot, Julien; Pinzan, Florian

    2017-03-01

    The development and integration of new materials and structures at the nanoscale require multiple parallel characterizations in order to control mostly physico-chemical properties as a function of applications. Among all properties, we can list physical properties such as: size, shape, specific surface area, aspect ratio, agglomeration/aggregation state, size distribution, surface morphology/topography, structure (including crystallinity and defect structure), solubility and chemical properties such as: structural formula/molecular structure, composition (including degree of purity, known impurities or additives), phase identity, surface chemistry (composition, charge, tension, reactive sites, physical structure, photocatalytic properties, zeta potential), hydrophilicity/lipophilicity. Depending on the final material formulation (aerosol, powder, nanostructuration…) and the industrial application (semiconductor, cosmetics, chemistry, automotive…), a fleet of complementary characterization equipments must be used in synergy for accurate process tuning and high production yield. The synergy between equipment so-called hybrid metrology consists in using the strength of each technique in order to reduce the global uncertainty for better and faster process control. The only way to succeed doing this exercise is to use data fusion methodology. In this paper, we will introduce the work that has been done to create the first generic hybrid metrology software platform dedicated to nanotechnologies process control. The first part will be dedicated to process flow modeling that is related to a fleet of metrology tools. The second part will introduce the concept of entity model which describes the various parameters that have to be extracted. The entity model is fed with data analysis as a function of the application (automatic analysis or semi-automated analysis). The final part will introduce two ways of doing data fusion on real data coming from imaging (SEM, TEM, AFM

  14. Editorial for the special issue dedicated to GOPV (Global Organic Photovoltaics Conference)

    DEFF Research Database (Denmark)

    Krebs, Frederik C

    2012-01-01

    and USA dedicated to the topic of OPV that attract participants from both the USA and Europe but relatively few from Asia. It is naïve to believe that OPV should not become a global effort and that developments would accelerate faster by maintaining this geographical imbalance. The aim with the GOPV......, degradation, stability, thermo-mechanical properties, roll-to-roll processing, manufacture and industrial aspects of the field. It is my hope that you will enjoy reading this extract from the GOPV conference that comprised 48 oral presentations, 24 poster presentations and had 114 participants from 18...

  15. Development of dedicated nuclear heating plants in the Federal Republic of Germany

    International Nuclear Information System (INIS)

    Goetzmann, C.A.; Schroeter, K.E.

    1988-01-01

    In many cases district heating is both economically and environmentally superior over directly burning of fossil fuels in individual furnaces primarily because of the efficiency of the usual applied co-generation principle with regard to fuel utilization and flue gas clean up. In principle, this argument should carry even greater weight in conjunction with nuclear energy. The major draw back of dedicated heating reactors as seen up to now concerns the high specific capital cost for the application-dictated small reactor size. The paper discusses by way of a specific example in what directions solutions are being sought

  16. Nurses caring for ENT patients in a district general hospital without a dedicated ENT ward score significantly less in a test of knowledge than nurses caring for ENT patients in a dedicated ENT ward in a comparable district general hospital.

    Science.gov (United States)

    Foxton, C R; Black, D; Muhlschlegel, J; Jardine, A

    2014-12-01

    To assess whether there is a difference in ENT knowledge amongst nurses caring for patients on a dedicated ENT ward and nurses caring for ENT patients in a similar hospital without a dedicated ENT ward. A test of theoretical knowledge of ENT nursing care was devised and administered to nurses working on a dedicated ENT ward and then to nurses working on generic non-subspecialist wards regularly caring for ENT patients in a hospital without a dedicated ENT ward. The test scores were then compared. A single specialist ENT/Maxillo-Facial/Opthalmology ward in hospital A and 3 generic surgical wards in hospital B. Both hospitals are comparable district general hospitals in the south west of England. Nursing staff working in hospital A and hospital B on the relevant wards were approached during the working day. 11 nurses on ward 1, 10 nurses on ward 2, 11 nurses on ward 3 and 10 nurses on ward 4 (the dedicated ENT ward). Each individual test score was used to generate an average score per ward and these scores compared to see if there was a significant difference. The average score out of 10 on ward 1 was 6.8 (+/-1.6). The average score on ward two was 4.8 (+/-1.6). The average score on ward three was 5.5 (+/-2.1). The average score on ward 4, which is the dedicated ENT ward, was 9.7 (+/-0.5). The differences in average test score between the dedicated ENT ward and all of the other wards are statistically significant. Nurses working on a dedicated ENT ward have an average higher score in a test of knowledge than nurses working on generic surgical wards. This difference is statistically significant and persists despite banding or training. © 2014 John Wiley & Sons Ltd.

  17. Genetic testing of aetiology of intellectual disability in a dedicated physical healthcare outpatient clinic for adults with intellectual disability.

    Science.gov (United States)

    Wallace, R A

    2016-02-01

    No guidelines exist for assessment of aetiology of intellectual disability in adults with intellectual disability by adult physicians, although robust guidelines exist for paediatric populations. It was speculated that the paediatric guidelines would also be suitable for adults. In rural/regional setting with limited clinical genetics, to perform a quality assurance evaluation on genetics assessment of aetiology of developmental disability in adults attending a dedicated healthcare clinic for adults with intellectual disability, compared results with paediatric standards, speculates if these seem appropriate for adults and speculates on a role for clinical genetics services. Retrospective chart audit of eligible patients looking at genetic clinical assessment, tests selected (molecular karyotype, G banding, metabolics), and yields of positive results. The results were compared with the recommended paediatric guidelines. Of 117 eligible adult patients, ideal genetic history was incomplete for 40% of patients without Down syndrome because of physician cause and lack of information. The number of abnormal genetic results increased from 46% to 66%, mainly from the molecular karyotype, though not all may have been clinically relevant. The improved yield from this test was similar to that in paediatric studies. Use of G banding and metabolic testing could be refined. Improvement can be made in clinical genetic assessment, but results generally support use of molecular karyotyping as first tier testing of cause of unknown intellectual disability in adults, as in the case for paediatric populations. The study highlights a necessary complementary role for clinical geneticists to interpret abnormal results. © 2016 Royal Australasian College of Physicians.

  18. Geomagnetic reversals, polar ice and cosmic spherules: some recent measurements with a small dedicated accelerator mass-spectrometry facility

    International Nuclear Information System (INIS)

    Raisbeck, G.M.; Yiou, F.

    1987-01-01

    We have developed techniques for measuring the cosmogenic isotopes 10 Be (half-life 1.5 Ma) and 26 Al (716 ka) by using a small (ca. 2.2 MV) dedicated accelerator mass spectrometer facility. Three recent applications of such measurements are as follows. 1. 10 Be has been measured in marine-sediment cores at levels corresponding to three recent geomagnetic reversals. We observe an increase in 10 Be production at each of these times. The results give information on the form and length of the geomagnetic intensity changes during a reversal, and the level at which magnetic remanence is acquired in the sediments. 2. 10 Be has been measured over a 2083 m ice core, corresponding to the last climatic cycle, recovered from Vostok, Antarctica. The results suggest that the precipitation rate during the last Ice Age was about half of its present rate. There are also some indications of fairly rapid 10 Be production changes. 3. 10 Be and 26 Al have been measured in 'cosmic spherules' (small round objects, ca. 500 μm diameter) recovered in deep-sea sediments and in melt lakes on Greenland ice. The results confirm an extraterrestrial origin for such objects, as well as indicating that the parent bodies of most of them were irradiated in space as small (less than 1 cm) objects. These spherules thus very probably represent cometary debris. (author)

  19. Dedicated very front-end electronics for an ILC prototype hadronic calorimeter with SiPM read-out

    CERN Document Server

    de La Taille, C

    2008-01-01

    The SPIROC chip is a dedicated very front-end electronics for an ILC prototype hadronic calorimeter with Silicon photomultiplier (or MPPC) readout. This ASIC is due to equip a 10,000-channel demonstrator in 2009. SPIROC is an evolution of FLC_SiPM used for the ILC AHCAL physics prototype [1]. SPIROC was submitted in June 2007 and will be tested in September 2007. It embeds cutting edge features that fulfil ILC final detector requirements. It has been realized in 0.35m SiGe technology. It has been developed to match the requirements of large dynamic range, low noise, low consumption, high precision and large number of readout channels needed. SPIROC is an auto-triggered, bi-gain, 36-channel ASIC which allows to measure on each channel the charge from one photoelectron to 2000 and the time with a 100ps accurate TDC. An analogue memory array with a depth of 16 for each channel is used to store the time information and the charge measurement. A 12-bit Wilkinson ADC has been embedded to digitize the analogue memor...

  20. Educational Technology Network: a computer conferencing system dedicated to applications of computers in radiology practice, research, and education.

    Science.gov (United States)

    D'Alessandro, M P; Ackerman, M J; Sparks, S M

    1993-11-01

    Educational Technology Network (ET Net) is a free, easy to use, on-line computer conferencing system organized and funded by the National Library of Medicine that is accessible via the SprintNet (SprintNet, Reston, VA) and Internet (Merit, Ann Arbor, MI) computer networks. It is dedicated to helping bring together, in a single continuously running electronic forum, developers and users of computer applications in the health sciences, including radiology. ET Net uses the Caucus computer conferencing software (Camber-Roth, Troy, NY) running on a microcomputer. This microcomputer is located in the National Library of Medicine's Lister Hill National Center for Biomedical Communications and is directly connected to the SprintNet and the Internet networks. The advanced computer conferencing software of ET Net allows individuals who are separated in space and time to unite electronically to participate, at any time, in interactive discussions on applications of computers in radiology. A computer conferencing system such as ET Net allows radiologists to maintain contact with colleagues on a regular basis when they are not physically together. Topics of discussion on ET Net encompass all applications of computers in radiological practice, research, and education. ET Net has been in successful operation for 3 years and has a promising future aiding radiologists in the exchange of information pertaining to applications of computers in radiology.

  1. [Patients' intervention in a therapeutic education program dedicated to systemic lupus: definitions, setting and benefits].

    Science.gov (United States)

    Hervier, B; Magar, Y; Allab, F; Richard, K; Neves, Y; Danjou, S; Amoura, Z; Ayçaguer, S

    2015-10-01

    Though recommended, participation of patients with specific expertise in therapeutic education programs (TEP) is rare. This work reports the experience of a national reference centre for rare systemic diseases. Involvement of "expert patients" (EP) has been planned from the development of a TEP dedicated to systemic lupus: patients' roles and required expertise have been defined and linked to the pedagogical tools. Such patients have been recruited during individual interviews and called to participate to specific pedagogical training. EP intervention have been evaluated by questionnaire to EP and health care providers. Three EP's functions have been identified: sharing experiences, giving "tips and tricks" and promoting dialogue. EP's interventions has been organised into a hierarchy (from sharing to co-animation). Among 298 patients enrolled in the TEP, 25 (8.4%) have been identified as possible EP. Eight of them (32%) benefited from a specific training of 12 hours. Among these patients, two (25%) regularly participate to the education sessions. For EP as well as for health care providers, EP's intervention seems beneficial (visual scale scores of 7.5 and 9.5, respectively). Though difficult to organise, EP's intervention in TEP dedicated to rare systemic diseases seems useful and would earn to be increase. Copyright © 2015 Société nationale française de médecine interne (SNFMI). Published by Elsevier SAS. All rights reserved.

  2. Technical features and experimental characterization of the IORT-1 system, a new IORT dedicated accelerator

    International Nuclear Information System (INIS)

    Ronsivalle, Concetta; Picardi, Luigi; Iacoboni, Vincenzo; Teodoli, Stefania; Barca, Giuliana; Siciliano, Roberto

    2006-01-01

    In the last years there has been an increasing interest on IORT (Intraoperative Radiation Therapy), also because of the development of dedicated accelerators. This technique represents a very effective oncological treatment consisting in delivering a single high dose on a tumour bed soon after surgery resection. The main advantage of IORT technique, in addition to the possibility to avoid additional radio-treatments after surgery intervention, is to be referred to the improved tumor local control: the technique allows the focusing of a high single dose only on diseased tissue, avoiding to irradiate healthy tissues and preventing tumor recurrence in surrounding area. An important pioneer work was done by ENEA (Italian National Agency for New Technologies, Energy and the Environment) that conceived in collaboration with the national industry since early '90 s the first mobile machines able to be used directly in the surgery room. Recently a new generation IORT dedicated system named IORT-1, based on a compact, low stray radiation linac with variable energy in a range 4-12 MeV has been built in the framework of the ENEA 'IORT project' funded by the Italian Ministry of Research (MIUR). In the following system, recently installed in the hospital of the 'Azienda Ospedaliera di Cosenza' in Southern Italy, is described and the results of the dosimetric measurements are shown

  3. Power electronic supply system with the wind turbine dedicated for average power receivers

    Science.gov (United States)

    Widerski, Tomasz; Skrzypek, Adam

    2018-05-01

    This article presents the original project of the AC-DC-AC converter dedicated to low power wind turbines. Such a set can be a good solution for powering isolated objects that do not have access to the power grid, for example isolated houses, mountain lodges or forester's lodges, where they can replace expensive diesel engine generators. An additional source of energy in the form of a mini-wind farm is also a good alternative to yachts, marinas and tent sites, which are characterized by relatively low power consumption. This article presents a designed low power wind converter that is dedicated to these applications. The main design idea of the authors was to create a device that converts the very wide range input voltage directly to a stable 230VAC output voltage without the battery buffer. Authors focused on maximum safety of using and service. The converter contains the thermal protection, short-circuit protection and overvoltage protection. The components have been selected in such a way as to ensure that the device functions as efficiently as possible.

  4. Measurement-based performance profiles and dynamics of UDT over dedicated connections

    Energy Technology Data Exchange (ETDEWEB)

    Foster, Ian [University of Chicago; Kettimuthu, R. [Argonne National Laboratory (ANL); Wu, Qishi [University of Memphis; Yun, Daqing [Harrisburg University; Rao, Nageswara S. [ORNL; Liu, Qiang [ORNL

    2016-11-01

    Wide-area data transfers in high-performance computing and big data scenarios are increasingly being carried over dedicated network connections that provide high capacities at low loss rates. UDP-based transport protocols are expected to be particularly well-suited for such transfers but their performance is relatively unexplored over a wide range of connection lengths, compared to TCP over shared connections. We present extensive throughput measurements of UDP-based Data Transfer (UDT) over a suite of physical and emulated 10 Gbps connections. In sharp contrast to current UDT analytical models, these measurements indicate much more complex throughput dynamics that are sensitive to the connection modality, protocol parameters, and round-trip times. Lyapunov exponents estimated from the Poincare maps of UDT traces clearly indicate regions of instability and complex dynamics. We propose a simple model based on the ramp-up and sustainment regimes of a generic transport protocol, which qualitatively illustrates the dominant monotonicity and concavity properties of throughput profiles and relates them to Lyapunov exponents. These measurements and analytical results together enable us to comprehensively evaluate UDT performance and select parameters to achieve high throughput, and they also provide guidelines for designing effective transport protocols for dedicated connections.

  5. Impact of a Dedicated Emergency Medicine Teaching Resident Rotation at a Large Urban Academic Center.

    Science.gov (United States)

    Ahn, James; Golden, Andrew; Bryant, Alyssa; Babcock, Christine

    2016-03-01

    In the face of declining bedside teaching and increasing emergency department (ED) crowding, balancing education and patient care is a challenge. Dedicated shifts by teaching residents (TRs) in the ED represent an educational intervention to mitigate these difficulties. We aimed to measure the perceived learning and departmental impact created by having TR. TRs were present in the ED from 12 pm-10 pm daily, and their primary roles were to provide the following: assist in teaching procedures, give brief "chalk talks," instruct junior trainees on interesting cases, and answer clinical questions in an evidence-based manner. This observational study included a survey of fourth-year medical students (MSs), residents and faculty at an academic ED. Surveys measured the perceived effect of the TR on teaching, patient flow, ease of procedures, and clinical care. Survey response rates for medical students, residents, and faculty are 56%, 77%, and 75%, respectively. MSs perceived improved procedure performance with TR presence and the majority agreed that the TR was a valuable educational experience. Residents perceived increased patient flow, procedure performance, and MS learning with TR presence. The majority agreed that the TR improved patient care. Faculty agreed that the TR increased resident and MS learning, as well as improved patient care and procedure performance. The presence of a TR increased MS and resident learning, improved patient care and procedure performance as perceived by MSs, residents and faculty. A dedicated TR program can provide a valuable resource in achieving a balance of clinical education and high quality healthcare.

  6. THE RAILMAPPER – A DEDICATED MOBILE LIDAR MAPPING SYSTEM FOR RAILWAY NETWORKS

    Directory of Open Access Journals (Sweden)

    J. Kremer

    2012-07-01

    Full Text Available The Mobile LiDAR Mapping System StreetMapper from IGI and 3D Laser Mapping (Bingham Nottingham, UK is mounted on a large variety of road vehicles to cover different mission specifications. In addition to the operation on the road, the system finds its applications on other kinds of vehicles, like boats or trains. The modular and flexible system concept even allows utilizing the same LiDAR Mapping system for Mobile Mapping on the ground and for airborne missions on helicopters, respectively. Besides this general flexibility, each application has its own special requirements. Special hardware and software components are needed to complete the core components, like the laser scanner and the GNSS/IMU systems, to build a dedicated system for the chosen task. Compared to the typical dynamics of a road vehicle mounted Mobile Mapping system, a dedicated rail mapping system operates under conditions that are much more challenging for a high accuracy GNSS/IMU trajectory determination. Furthermore, the typical rail mapping tasks, like the exact measurement of the rail track geometry, require the operation of the most accurate laser scanners and of specialized post-processing software. In this paper, the RailMapper, a specialized Mobile Mapping system for railway surveys is presented. The system is described with focus on the railway specific requirements and results of practical surveys are given.

  7. Detector design issues for compact nuclear emission cameras dedicated to breast imaging

    International Nuclear Information System (INIS)

    Levin, Craig S.

    2003-01-01

    Certain gamma ray and positron emitting radiotracers have shown great promise for use in the detection, diagnosis and staging of breast cancer. Unfortunately, standard nuclear emission cameras (SPECT, PET) found in the clinic are not practical for breast imaging of these emissions due to inadequate spatial and energy resolutions and sensitivity, large and awkward size, and relatively high cost per study. High spatial and energy resolutions and sensitivity are needed for good lesion detectability. Due to these limitations of standard cameras, there has been recent research into the development of small, compact nuclear emission imagers dedicated for close-proximity breast imaging. The small detector head size means a variety of exotic detectors or collimators may be implemented to improve spatial and energy resolution and sensitivity performances at a reasonable cost. In this paper, we will present some of the compact gamma ray and annihilation photon imaging detector designs that have been proposed and/or developed for dedicated breast imaging. We will review the physics and discuss the advantages and disadvantages of various detector configurations. Finally we will estimate the fundamental spatial resolution potential available with close-proximity nuclear emission imaging and discuss how one may approach those limits through proper detector design

  8. Release to the gas phase of metals, S and Cl during combustion of dedicated waste fractions

    DEFF Research Database (Denmark)

    Pedersen, Anne Juul; van Lith, Simone Cornelia; Frandsen, Flemming

    2010-01-01

    The release to the gas phase of inorganic elements such as alkali metals. Cl, S, and heavy metals in Waste-to-Energy (WtE) boilers is a challenge. Besides the risk of harmful emissions to the environment, inorganic elements released from the grate may cause severe ash deposition and corrosion...... and the link to the formation of fly ash and aerosols in full-scale waste incinerators. The release of metals, S and Cl from four dedicated waste fractions was quantified as a function of temperature in a lab-scale fixed-bed reactor. The waste fractions comprised chromated copper arsenate (CCA) impregnated....... The lab-scale release results were then compared with results from a related, full-scale partitioning study, in which test runs with the addition of similar, dedicated waste fractions to a base-load waste had been performed in a grate-fired WtE boiler. In general, the elements Al, Ca, Cr, Cu, Fe, Mg, Si...

  9. Evaluation of the 1Shot Phantom dedicated to the mammography system using FCR

    International Nuclear Information System (INIS)

    Nagashima, Chieko; Uchiyama, Nachiko; Moriyama, Noriyuki; Nagata, Mio; Kobayashi, Hiroyuki; Sankoda, Katsuhiro; Saotome, Shigeru; Tagi, Masahiro; Kusunoki, Tetsurou

    2009-01-01

    Currently daily quality control (QC) tests for mammography systems are generally evaluated by using visual analysis phantoms, which of course means subjective measurement. In our study, however, we evaluated a novel digital phantom, the 1Shot Phantom M plus (1Shot Phantom), together with automatic analysis software dedicated for mammography systems using Fuji computed radiography (FCR). The digital phantom enables objective evaluation by providing for actual physical measurement rather than subjective visual assessment. We measured contrast to noise ratio (CNR), image receptor homogeneity, missed tissue at chest wall side, modulation transfer function (MTF), and geometric distortion utilizing the 1Shot Phantom. We then compared the values obtained using the 1Shot Phantom with values obtained from the European guidelines and International Electrotechnical Commission (IEC) standards. In addition, we evaluated the convenience of using the digital phantom. The values utilizing the 1Shot Phantom and those from the European guidelines and IEC standards were consistent, but the QC tests for the European guidelines and IEC standards methods took about six hours while the same QC tests using the 1Shot Phantom took 10 minutes or less including exposure of the phantom image, measurement, and analysis. In conclusion, the digital phantom and dedicated software proved very useful and produced improved analysis for mammography systems using FCR in clinical daily QC testing because of their objectivity and substantial time-saving convenience. (author)

  10. Dedicated Industrial Oilseed Crops as Metabolic Engineering Platforms for Sustainable Industrial Feedstock Production.

    Science.gov (United States)

    Zhu, Li-Hua; Krens, Frans; Smith, Mark A; Li, Xueyuan; Qi, Weicong; van Loo, Eibertus N; Iven, Tim; Feussner, Ivo; Nazarenus, Tara J; Huai, Dongxin; Taylor, David C; Zhou, Xue-Rong; Green, Allan G; Shockey, Jay; Klasson, K Thomas; Mullen, Robert T; Huang, Bangquan; Dyer, John M; Cahoon, Edgar B

    2016-02-26

    Feedstocks for industrial applications ranging from polymers to lubricants are largely derived from petroleum, a non-renewable resource. Vegetable oils with fatty acid structures and storage forms tailored for specific industrial uses offer renewable and potentially sustainable sources of petrochemical-type functionalities. A wide array of industrial vegetable oils can be generated through biotechnology, but will likely require non-commodity oilseed platforms dedicated to specialty oil production for commercial acceptance. Here we show the feasibility of three Brassicaceae oilseeds crambe, camelina, and carinata, none of which are widely cultivated for food use, as hosts for complex metabolic engineering of wax esters for lubricant applications. Lines producing wax esters >20% of total seed oil were generated for each crop and further improved for high temperature oxidative stability by down-regulation of fatty acid polyunsaturation. Field cultivation of optimized wax ester-producing crambe demonstrated commercial utility of these engineered crops and a path for sustainable production of other industrial oils in dedicated specialty oilseeds.

  11. Challenges and models in supporting logistics system design for dedicated-biomass-based bioenergy industry.

    Science.gov (United States)

    Zhu, Xiaoyan; Li, Xueping; Yao, Qingzhu; Chen, Yuerong

    2011-01-01

    This paper analyzed the uniqueness and challenges in designing the logistics system for dedicated biomass-to-bioenergy industry, which differs from the other industries, due to the unique features of dedicated biomass (e.g., switchgrass) including its low bulk density, restrictions on harvesting season and frequency, content variation with time and circumambient conditions, weather effects, scattered distribution over a wide geographical area, and so on. To design it, this paper proposed a mixed integer linear programming model. It covered from planting and harvesting switchgrass to delivering to a biorefinery and included the residue handling, concentrating on integrating strategic decisions on the supply chain design and tactical decisions on the annual operation schedules. The present numerical examples verified the model and demonstrated its use in practice. This paper showed that the operations of the logistics system were significantly different for harvesting and non-harvesting seasons, and that under the well-designed biomass logistics system, the mass production with a steady and sufficient supply of biomass can increase the unit profit of bioenergy. The analytical model and practical methodology proposed in this paper will help realize the commercial production in biomass-to-bioenergy industry. Copyright © 2010 Elsevier Ltd. All rights reserved.

  12. Automated Integration of Dedicated Hardwired IP Cores in Heterogeneous MPSoCs Designed with ESPAM

    Directory of Open Access Journals (Sweden)

    Ed Deprettere

    2008-06-01

    Full Text Available This paper presents a methodology and techniques for automated integration of dedicated hardwired (HW IP cores into heterogeneous multiprocessor systems. We propose an IP core integration approach based on an HW module generation that consists of a wrapper around a predefined IP core. This approach has been implemented in a tool called ESPAM for automated multiprocessor system design, programming, and implementation. In order to keep high performance of the integrated IP cores, the structure of the IP core wrapper is devised in a way that adequately represents and efficiently implements the main characteristics of the formal model of computation, namely, Kahn process networks, we use as an underlying programming model in ESPAM. We present details about the structure of the HW module, the supported types of IP cores, and the minimum interfaces these IP cores have to provide in order to allow automated integration in heterogeneous multiprocessor systems generated by ESPAM. The ESPAM design flow, the multiprocessor platforms we consider, and the underlying programming (KPN model are introduced as well. Furthermore, we present the efficiency of our approach by applying our methodology and ESPAM tool to automatically generate, implement, and program heterogeneous multiprocessor systems that integrate dedicated IP cores and execute real-life applications.

  13. Microwave tomography of extremities: 1. Dedicated 2D system and physiological signatures

    International Nuclear Information System (INIS)

    Semenov, Serguei; Nair, Bindu; Kellam, James; Williams, Thomas; Quinn, Michael; Sizov, Yuri; Nazarov, Alexei; Pavlovsky, Andrey; Posukh, Vitaly

    2011-01-01

    Microwave tomography (MWT) is a novel imaging modality which might be applicable for non-invasive assessment of functional and pathological conditions of biological tissues. Imaging of the soft tissue of extremities is one of its potential applications. The feasibility of this technology for such applications was demonstrated earlier. This is the first of two companion papers focused on an application of MWT for imaging of the extremity's soft tissues. The goal of this study is to assess the technical performance of the developed 2D MWT system dedicated for imaging of functional and pathological conditions of the extremity's soft tissues. Specifically, the system's performance was tested by its ability to detect signals associated with physiological activity and soft tissue interventions (circulatory related changes, blood flow reduction and a simulated compartmental syndrome)-the so-called physiological signatures. The developed 2D MWT system dedicated to the imaging of animal extremities demonstrates good technical performance allowing for stable and predictable data acquisition with reasonable agreement between the experimentally measured electromagnetic (EM) field and the simulated EM field within a measurement domain. Using the system, we were able to obtain physiological signatures associated with systolic versus diastolic phases of circulation in an animal extremity, reperfusion versus occlusion phases of the blood supply to the animal's extremity and a compartment syndrome. The imaging results are presented and discussed in the second companion paper.

  14. SLAPex Freeze/Thaw 2015: The First Dedicated Soil Freeze/Thaw Airborne Campaign

    Science.gov (United States)

    Kim, Edward; Wu, Albert; DeMarco, Eugenia; Powers, Jarrett; Berg, Aaron; Rowlandson, Tracy; Freeman, Jacqueline; Gottfried, Kurt; Toose, Peter; Roy, Alexandre; hide

    2016-01-01

    Soil freezing and thawing is an important process in the terrestrial water, energy, and carbon cycles, marking the change between two very different hydraulic, thermal, and biological regimes. NASA's Soil Moisture Active/Passive (SMAP) mission includes a binary freeze/thaw data product. While there have been ground-based remote sensing field measurements observing soil freeze/thaw at the point scale, and airborne campaigns that observed some frozen soil areas (e.g., BOREAS), the recently-completed SLAPex Freeze/Thaw (F/T) campaign is the first airborne campaign dedicated solely to observing frozen/thawed soil with both passive and active microwave sensors and dedicated ground truth, in order to enable detailed process-level exploration of the remote sensing signatures and in situ soil conditions. SLAPex F/T utilized the Scanning L-band Active/Passive (SLAP) instrument, an airborne simulator of SMAP developed at NASA's Goddard Space Flight Center, and was conducted near Winnipeg, Manitoba, Canada, in October/November, 2015. Future soil moisture missions are also expected to include soil freeze/thaw products, and the loss of the radar on SMAP means that airborne radar-radiometer observations like those that SLAP provides are unique assets for freeze/thaw algorithm development. This paper will present an overview of SLAPex F/T, including descriptions of the site, airborne and ground-based remote sensing, ground truth, as well as preliminary results.

  15. [F-18]FDG imaging of head and neck tumors: comparison of hybrid PET, dedicated PET and CT

    International Nuclear Information System (INIS)

    Dresel, S.; Brinkbaeumer, K.; Schmid, R.; Poepperl, G.; Hahn, K.; Szeimies, U.

    2001-01-01

    Aim: Aim of the study was to evaluate [F-18]FDG imaging of head and neck tumors using a Hybrid-PET device of the 2nd or 3rd generation. Examinations were compared to dedicated PET and Spiral-CT. Methods: 54 patients suffering from head and neck tumors were examined using dedicated PET and Hybrid-PET after injection of 185-350 MBq [F-18]FDG. Examinations were carried out on the dedicated PET first followed by a scan on the Hybrid-PET. Dedicated PET was acquired in 3D mode, Hybrid-PET was performed in list mode using an axial filter. Reconstruction of data was performed iteratively on both, dedicated PET and Hybrid-PET. All patients received a CT scan in multislice technique. All finding have been verified by the goldstandard histology or in case of negative histology by follow up. Results: Using dedicated PET the primary or recurrent lesion was correctly diagnosed in 47/48 patients, using Hybrid-PET in 46/48 patients and using CT in 25/48 patients. Metastatic disease in cervical lymph nodes was diagnosed in 17/18 patients with dedicated PET, in 16/18 patients with Hybrid-PET and in 15/18 with CT. False positive results with regard to lymph node metastasis were seen with one patient for dedicated PET and Hybrid-PET, respectively, and with 18 patients for CT. In a total of 11 patients unknown metastastic lesions were seen with dedicated PET and with Hybrid-PET elsewhere in the body. Additional malignant disease other than the head and neck tumor was found in 4 patients. Conclusion: Using Hybrid-PET for [F-18]FDG imaging reveals a loss of sensitivity and specificity of about 1-5% as compared to dedicated PET in head and neck tumors. [F-18]FDG PET with both, dedicated PET and Hybrid-PET is superior to CT in the diagnosis of primary or recurrent lesions as well as in the assessment of lymph node involvement. (orig.) [de

  16. Development of Metal/Polymer Mixtures Dedicated to Macro and Micro powder Injection Moulding : Experiments and Simulations

    International Nuclear Information System (INIS)

    Quinard, C.; Barriere, T.; Gelin, J. C.; Song, J. P.; Cheng, Z. Q.; Liu, B. S.

    2007-01-01

    Important research tasks at ENSMM/LMA are concerned for the development of mixtures of fine powders associated to polymer binders dedicated to the powder injection moulding (PIM) and to the powder injection micro-moulding (μPIM) in accordance with many works already carried out with different feedstock suppliers dedicated to the macro-components. These research tasks are completed with the simulations of injection and sintering for solid state diffusion for to validate the mumerical models

  17. MRI performed on dedicated knee coils is inaccurate for the measurement of tibial tubercle trochlear groove distance

    International Nuclear Information System (INIS)

    Aarvold, A.; Pope, A.; Sakthivel, V.K.; Ayer, R.V.

    2014-01-01

    Tibial tubercle trochlear groove distance (TTD) is a significant factor in patello-femoral instability. Initially described on CT scans with the knee in full extension, the measurement has been validated on MR scans. Dedicated knee MRI coils have subsequently superseded both CT and MRI body coils for knee imaging. However, the knee rests in partial flexion within the dedicated knee coil. The objective of this study is to investigate whether images from dedicated knee MRI coils produce different TTD measurements from MR body coils. Thirty-two symptomatic knees (27 patients) had simultaneous knee MR scans performed in both a dedicated knee coil and a body coil. TTD measurements were independently compared to assess whether the coil type used affected TTD. Patients' ages ranged from 10 to 27 years (mean 15 years). Mean TTD in the dedicated knee coil (partially flexed knee) was 11.3 mm compared with 19.9 mm in the body coil (that permits full knee extension). The mean difference was 8.6 mm, which was highly significant (p < 0.0001, unpaired t test). Inter-rater correlation co-efficient was 96 %. Of the knees that recorded a ''normal'' TTD on the dedicated knee coil, 60-100 % recorded a ''pathological'' TTD on body coil images, depending on which diagnostic value for ''normal'' cut-off was used. This study has identified a highly significant difference in TTD measurement when knees are scanned in a dedicated knee coil with the knee partially flexed, compared with an MR body coil. It is critical for surgeons and radiologists managing patello-femoral instability to appreciate this profound difference. TTD measurement taken from knees scanned in dedicated knee coils may lead to patients being falsely re-assured or erroneously denied surgery. (orig.)

  18. A miniature TDCR system dedicated to in-situ activity assay

    International Nuclear Information System (INIS)

    Johansson, Lena; Bakhshandeiar, Eleanor; Pearce, Andy; Collins, Sean; Orlandini, Pascal; Sephton, John

    2014-01-01

    In the framework of the European Metrology Research Programme (EMRP), the Joint Research Project MetroFission has a dedicated work package for the development of a portable Triple-to-Double-Coincidence-Ratio (TDCR) system dedicated to in-situ activity measurements of low-energy beta emitters arising from the operation of the next generation of nuclear power plants. In the design phase of the NPL version of the mini-TDCR, a wide range of metrological aspects and detector types was considered. This paper summarizes these aspects of design, in the light of previous experience with the primary TDCR system at NPL. For example, in this miniature version of the TDCR, the optical chamber was simplified and cylindrical geometry was deemed sufficient. The reflectivity of the surface was increased by painted layers of Spectraflect ® , a specially formulated barium sulphate coating with high reflectivity across a wide range of wave lengths including UV. This option was chosen rather than the high performing and more expensive Spectralon ® material used for the primary NPL TDCR. The miniature TDCR system is intended for on-site monitoring and will not require as high a performance as the primary system. Other factors that were considered included sample changing, light tightness, type of photo detector, method for varying the detection efficiency, shielding and the possible addition of an internal gamma-ray source for determination of the quench parameter of the source. In this version, the sample changing is performed using a piston and an automatic shutter. Significant design effort has been applied to ensure minimal ingress of light from the piston. Efficiency variation is accomplished by increasing the vertical displacement of the vial. Provision has been made to automate this at a later stage. Maximum light transmission to the photo-multiplier tubes is obtained at the “zero” reference height. Validation measurements were successfully performed using four different

  19. Scaling-law for the energy dependence of anatomic power spectrum in dedicated breast CT

    Energy Technology Data Exchange (ETDEWEB)

    Vedantham, Srinivasan; Shi, Linxi; Glick, Stephen J.; Karellas, Andrew [Department of Radiology, University of Massachusetts Medical School, Worcester, Massachusetts 01655 (United States)

    2013-01-15

    Purpose: To determine the x-ray photon energy dependence of the anatomic power spectrum of the breast when imaged with dedicated breast computed tomography (CT). Methods: A theoretical framework for scaling the empirically determined anatomic power spectrum at one x-ray photon energy to that at any given x-ray photon energy when imaged with dedicated breast CT was developed. Theory predicted that when the anatomic power spectrum is fitted with a power curve of the form k f{sup -{beta}}, where k and {beta} are fit coefficients and f is spatial frequency, the exponent {beta} would be independent of x-ray photon energy (E), and the amplitude k scales with the square of the difference in energy-dependent linear attenuation coefficients of fibroglandular and adipose tissues. Twenty mastectomy specimens based numerical phantoms that were previously imaged with a benchtop flat-panel cone-beam CT system were converted to 3D distribution of glandular weight fraction (f{sub g}) and were used to verify the theoretical findings. The 3D power spectrum was computed in terms of f{sub g} and after converting to linear attenuation coefficients at monoenergetic x-ray photon energies of 20-80 keV in 5 keV intervals. The 1D power spectra along the axes were extracted and fitted with a power curve of the form k f{sup -{beta}}. The energy dependence of k and {beta} were analyzed. Results: For the 20 mastectomy specimen based numerical phantoms used in the study, the exponent {beta} was found to be in the range of 2.34-2.42, depending on the axis of measurement. Numerical simulations agreed with the theoretical predictions that for a power-law anatomic spectrum of the form k f{sup -{beta}}, {beta} was independent of E and k(E) =k{sub 1}[{mu}{sub g}(E) -{mu}{sub a}(E)]{sup 2}, where k{sub 1} is a constant, and {mu}{sub g}(E) and {mu}{sub a}(E) represent the energy-dependent linear attenuation coefficients of fibroglandular and adipose tissues, respectively. Conclusions: Numerical

  20. A dedicated AMS setup for medium mass isotopes at the Cologne FN tandem accelerator

    Science.gov (United States)

    Schiffer, M.; Altenkirch, R.; Feuerstein, C.; Müller-Gatermann, C.; Hackenberg, G.; Herb, S.; Bhandari, P.; Heinze, S.; Stolz, A.; Dewald, A.

    2017-09-01

    AMS measurements of medium mass isotopes, e.g. of 53Mn and 60Fe, are gaining interest in various fields of operation, especially geoscience. Therefore a dedicated AMS setup has been built at the Cologne 10 MV FN tandem accelerator. This setup is designed to obtain a sufficient suppression of the stable isobars at energies around 100 MeV. In this contribution we report on the actual status of the new setup and the first in-beam tests of its individual components. The isobar suppression is done with (dE/dx) techniques using combinations of energy degrader foils with an electrostatic analyzer (ESA) and a time of flight (ToF) system, as well as a (dE/dx),E gas ionization detector. Furthermore, the upgraded ion source and its negative ion yield measurement for MnO- are presented.

  1. Introduction of the commercial grade dedication into Nuclear Power Plant Krsko (NEK) procurement process

    International Nuclear Information System (INIS)

    Heruc, Z.; Gajsak, Z.; Nikpalj, R.

    1996-01-01

    NEK management has undertaken a set of actions to improve the ability to provide equipment, spare parts and material needed to support operation and maintenance of the Krsko plant. These actions are necessary due primarily to the fact that NEK is more and more confronted (increasing trend) with the issue that suppliers of safety-related equipment and spare parts have decided not to pursue the nuclear portion of their business, incl. specific QA systems and qualifications. The purchase orders imposing these requirements are no longer accepted. In order to continue to obtain the necessary materials at the required quality level, a 'Commercial Grade Item' (CGI) procurement and dedication program has been developed based on similar practices in USA. (author)

  2. Introduction of the commercial grade dedication into Nuclear Power Plant Krsko (NEK) procurement process

    International Nuclear Information System (INIS)

    Heruc, Z.; Gajsak, Z.; Nikpalj, R.

    1996-01-01

    NEK management has undertaken a set of actions to improve the ability to provide equipment, spare parts and material needed to support operation and maintenance of the Krsko plant. These actions are necessary due primarily to the fact that NEK is more and more confronted (increasing trend) with the issue that suppliers of safety-related equipment and spare parts have decided not to pursue the nuclear portion of their business, incl. specific QA systems and qualifications. The purchase orders imposing these requirements are no longer accepted. In order to continue to obtain the necessary materials at the required quality level, a 'Commercial Grade Item' (CGI) procurement and dedication program has been developed based on similar practices in the USA. (author)

  3. Mandatory special or dedicated trains for radioactive materials shipments evidence shows they're not needed

    International Nuclear Information System (INIS)

    Goodman, L.S.; Garrison, R.F.; Harmon, L.H.

    1988-01-01

    The rejection of mandatory special or dedicated trains by all responsible Federal agencies for transportation of radioactive materials in shielded casks has a long history. Working with the railroads and the National Academy of Sciences, the ICC adopted standards for transporting radioactive materials in regular freight trains in the mid 1940's. The standards rested primarily on ensuring the integrity of the radioactive materials packaging. AEC, then NRC and DOT, followed the ICC lead, supplementing the licensing rules for casks with a series of performance or stress tests. At no time did these agencies require special trains or special routing for rail casks. Mandatory special trains have too many disadvantages without any proven safety benefit to be worth their high cost to the shipper. The ICC, in a series of litigated cases, found that given the strength of the casks, mandatory special trains were wasteful transportation and an unreasonable railroad practice

  4. Definition of natural T cell antigens with mimicry epitopes obtained from dedicated synthetic peptide libraries.

    Science.gov (United States)

    Hiemstra, H S; van Veelen, P A; Schloot, N C; Geluk, A; van Meijgaarden, K E; Willemen, S J; Leunissen, J A; Benckhuijsen, W E; Amons, R; de Vries, R R; Roep, B O; Ottenhoff, T H; Drijfhout, J W

    1998-10-15

    Progress has recently been made in the use of synthetic peptide libraries for the identification of T cell-stimulating ligands. T cell epitopes identified from synthetic libraries are mimics of natural epitopes. Here we show how the mimicry epitopes obtained from synthetic peptide libraries enable unambiguous identification of natural T cell Ags. Synthetic peptide libraries were screened with Mycobacterium tuberculosis-reactive and -autoreactive T cell clones. In two cases, database homology searches with mimicry epitopes isolated from a dedicated synthetic peptide library allowed immediate identification of the natural antigenic protein. In two other cases, an amino acid pattern that reflected the epitope requirements of the T cell was determined by substitution and omission mixture analysis. Subsequently, the natural Ag was identified from databases using this refined pattern. This approach opens new perspectives for rapid and reliable Ag definition, representing a feasible alternative to the biochemical and genetic approaches described thus far.

  5. Fast Oblivious AES A Dedicated application of the MiniMac protocol

    DEFF Research Database (Denmark)

    Zakarias, Rasmus Winther; Damgård, Ivan Bjerre

    2015-01-01

    We present an actively secure multi-partycomputation of the Advanced Encryption Standard (AES). To the best of our knowledge it is the fastest of its kind to date. We start from an efficient actively secure evaluation of general binary circuits that was implemented by the authors of [DLT14......]. They presented an optimized implementation of the so-called MiniMac protocol [DZ13] that runs in the pre-processing model, and applied this to a binary AES circuit. In this paper we de- scribe how to dedicate the pre-processing to the structure of AES, which improves significantly the throughput and latency...... of previous actively secure implementations. We get a latency of about 6 ms and amortised time about 0.4 ms per AES block, which seems completely adequate for practical applications such as verification of 1-time passwords....

  6. The linac and booster RF systems for a dedicated injector for SPEAR

    International Nuclear Information System (INIS)

    Weaver, J.N.; Baird, S.; Baltay, M.; Borland, M.; Nuhn, H.D.; Safranek, J.; Chavis, C.; Emery, L.; Genin, R.D.; Hettel, R.; Morales, H.; Sebek, J.; Voss, J.; Wang, D.; Wiedemann, H.; Youngmann, B.; Miller, R.H.

    1991-01-01

    A 120 MeV, 2,856 MHz, TW linac, with a microwave gun, alpha magnet, and chopper, has been built at SSRL as a preinjector for and along with a 3 GeV booster synchrotron ring. The resulting injector will be available on demand to fill SPEAR, which is a storage ring now dedicated to synchrotron light production. The linac sections were purchased from China, the XK-5 klystrons were obtained surplus from SLAC, the modulators are a variation on those at SLAC and were built by SSRL, the alpha magnet and chopper were designed and built at SSRL and the microwave gun was designed and built in collaboration with Varian Associates. The RF system for the booster ring is similar to those at SPEAR and PEP and was built by SSRL. Some of the interesting mechanical and electrical details are discussed and the operating characteristics of the linac and ring RF system are highlighted

  7. The linac and booster RF systems for a dedicated injector for SPEAR

    International Nuclear Information System (INIS)

    Weaver, J.N.; Baird, S.; Baltay, M.; Borland, M.; Nuhn, H.D.; Safranek, J.; Chavis, C.; Emery, L.; Genin, R.D.; Hettel, R.; Morales, H.; Sebek, J.; Voss, J.; Wang, H.; Wiedemann, H.; Youngmann, B.

    1991-05-01

    A 120 MeV, 2856 MHz, TW linac, with a microwave gun, alpha magnet, and chopper, has been built at SSRL as a preinjector for and along with a 3 GeV booster synchrotron ring. The resulting injector will be available on demand to fill SPEAR, which is a storage ring now dedicated to synchrotron light production. The linac sections were purchased from China, the XK-5 klystrons were obtained surplus from SLAC, the modulators are a variation on those at SLAC and were built by SSRL, the alpha magnet and chopper were designed and built at SSRL and the microwave gun was designed and built in collaboration with Varian Associates. The rf system for the booster ring is similar to those at SPEAR and PEP and was built by SSRL. Some of the interesting mechanical and electrical details are discussed and the operating characteristics of the linac and ring rf system are highlighted. 8 refs., 6 figs

  8. FEM BASED PARAMETRIC DESIGN STUDY OF TIRE PROFILE USING DEDICATED CAD MODEL AND TRANSLATION CODE

    Directory of Open Access Journals (Sweden)

    Nikola Korunović

    2014-12-01

    Full Text Available In this paper a finite element method (FEM based parametric design study of the tire profile shape and belt width is presented. One of the main obstacles that similar studies have faced is how to change the finite element mesh after a modification of the tire geometry is performed. In order to overcome this problem, a new approach is proposed. It implies automatic update of the finite elements mesh, which follows the change of geometric design parameters on a dedicated CAD model. The mesh update is facilitated by an originally developed mapping and translation code. In this way, the performance of a large number of geometrically different tire design variations may be analyzed in a very short time. Although a pilot one, the presented study has also led to the improvement of the existing tire design.

  9. Commissioning Procedures for Mechanical Precision and Accuracy in a Dedicated LINAC

    International Nuclear Information System (INIS)

    Ballesteros-Zebadua, P.; Larrga-Gutierrez, J. M.; Garcia-Garduno, O. A.; Juarez, J.; Prieto, I.; Moreno-Jimenez, S.; Celis, M. A.

    2008-01-01

    Mechanical precision measurements are fundamental procedures for the commissioning of a dedicated LINAC. At our Radioneurosurgery Unit, these procedures can be suitable as quality assurance routines that allow the verification of the equipment geometrical accuracy and precision. In this work mechanical tests were performed for gantry and table rotation, obtaining mean associated uncertainties of 0.3 mm and 0.71 mm, respectively. Using an anthropomorphic phantom and a series of localized surface markers, isocenter accuracy showed to be smaller than 0.86 mm for radiosurgery procedures and 0.95 mm for fractionated treatments with mask. All uncertainties were below tolerances. The highest contribution to mechanical variations is due to table rotation, so it is important to correct variations using a localization frame with printed overlays. Mechanical precision knowledge would allow to consider the statistical errors in the treatment planning volume margins

  10. Dedicated Stereophotogrammetric X-Ray System For Craniofacial Research And Treatment Planning

    Science.gov (United States)

    Baumrind, Sheldon; Moffitt, Francis; Curry, Sean; Isaacson, Robert J.

    1983-07-01

    We have constructed and brought into use what we believe to be the first dedicated coplanar craniofacial stereometric x-ray system for clinical use. Paired Machlett Dynamax 50/58 x-ray tubes with 0.3 mm focal spots are employed. Displacement between emitters is 16 inches. The focus film distance for both emitters is 66.5 inches. The mid-sagittal plane to focus distance is 60 inches. One film of each stereo pair conforms with the standards of the Second Roentgenocephalometric Workshop and can be used to make all standard two-dimensional orthodontic and cephalometric measurements. When supplemented by data from the conjugate film, a three-dimensional coordinate map can be generated as a machine operation. Specialized complementary software has been developed to increase the reliability of landmark location both in two and in three dimensions.

  11. Assessment of dedicated revenue of non-educational hospitals in Guilan University of Medical Sciences (2012

    Directory of Open Access Journals (Sweden)

    S. Asefzadeh

    2015-06-01

    Full Text Available Hospitals, as one of the main providers of health services, are of great importance in health and economy. The aim of this descriptive study was to assess the dedicated revenue of all non-educational hospitals in Guilan University of Medical Sciences (14 hospitals in 2012. On average, 22.35% of income was provided by cash earnings and 77.65% was provided by insurance organizations.There was 1.25% deficit by insurance. The net income of small hospitals with few available beds was very low and they were not economically affordable. The out of pocket to total income ratio was higher in the hospitals located in deprived areas due to lack of full insurance coverage.

  12. Spatially-resolved EEL studies of plasmons in silver filled carbon nanotubes using a dedicated STEM

    International Nuclear Information System (INIS)

    Bangert, U; Harvey, A J; Seepujak, A

    2008-01-01

    Using a dedicated FEG STEM, we present highly spatially-resolved electron energy-loss (EEL) studies of individual multi-walled carbon nanotubes (MWCNTs), each with the inner cavity possessing regions completely filled with silver. The transmission and attenuation of graphite π-collective mode E-fields through the MWCNT walls are established. Noticeable changes in the graphite π-surface mode are witnessed, concomitant with coupling of the silver Mie mode and the graphite π-surface mode. The resulting collective mode is significantly red-shifted to below 5 eV, with considerable intensity in the visible frequency regime. It appears that silver retains its ability to enhance E-fields when surrounded by a MWCNT. Present observations lead to the possibility of collective modes propagating on graphene monolayers being tuned in frequency by the presence of a metal.

  13. Indefinite inner product spaces, Schur analysis, and differential equations a volume dedicated to Heinz Langer

    CERN Document Server

    Kirstein, Bernd

    2018-01-01

    This volume, which is dedicated to Heinz Langer, includes biographical material and carefully selected papers. Heinz Langer has made fundamental contributions to operator theory. In particular, he has studied the domains of operator pencils and nonlinear eigenvalue problems, the theory of indefinite inner product spaces, operator theory in Pontryagin and Krein spaces, and applications to mathematical physics. His works include studies on and applications of Schur analysis in the indefinite setting, where the factorization theorems put forward by Krein and Langer for generalized Schur functions, and by Dijksma-Langer-Luger-Shondin, play a key role. The contributions in this volume reflect Heinz Langer’s chief research interests and will appeal to a broad readership whose work involves operator theory.  .

  14. Parallel-aware, dedicated job co-scheduling within/across symmetric multiprocessing nodes

    Science.gov (United States)

    Jones, Terry R.; Watson, Pythagoras C.; Tuel, William; Brenner, Larry; ,Caffrey, Patrick; Fier, Jeffrey

    2010-10-05

    In a parallel computing environment comprising a network of SMP nodes each having at least one processor, a parallel-aware co-scheduling method and system for improving the performance and scalability of a dedicated parallel job having synchronizing collective operations. The method and system uses a global co-scheduler and an operating system kernel dispatcher adapted to coordinate interfering system and daemon activities on a node and across nodes to promote intra-node and inter-node overlap of said interfering system and daemon activities as well as intra-node and inter-node overlap of said synchronizing collective operations. In this manner, the impact of random short-lived interruptions, such as timer-decrement processing and periodic daemon activity, on synchronizing collective operations is minimized on large processor-count SPMD bulk-synchronous programming styles.

  15. Dedicated mobile high resolution prostate PET imager with an insertable transrectal probe

    Science.gov (United States)

    Majewski, Stanislaw; Proffitt, James

    2010-12-28

    A dedicated mobile PET imaging system to image the prostate and surrounding organs. The imaging system includes an outside high resolution PET imager placed close to the patient's torso and an insertable and compact transrectal probe that is placed in close proximity to the prostate and operates in conjunction with the outside imager. The two detector systems are spatially co-registered to each other. The outside imager is mounted on an open rotating gantry to provide torso-wide 3D images of the prostate and surrounding tissue and organs. The insertable probe provides closer imaging, high sensitivity, and very high resolution predominately 2D view of the prostate and immediate surroundings. The probe is operated in conjunction with the outside imager and a fast data acquisition system to provide very high resolution reconstruction of the prostate and surrounding tissue and organs.

  16. Indoor air quality of everyday use spaces dedicated to specific purposes-a review.

    Science.gov (United States)

    Marć, Mariusz; Śmiełowska, Monika; Namieśnik, Jacek; Zabiegała, Bożena

    2018-01-01

    According to literature data, some of the main factors which significantly affect the quality of the indoor environment in residential households or apartments are human activities such as cooking, smoking, cleaning, and indoor exercising. The paper presents a literature overview related to air quality in everyday use spaces dedicated to specific purposes which are integral parts of residential buildings, such as kitchens, basements, and individual garages. Some aspects of air quality in large-scale car parks, as a specific type of indoor environment, are also discussed. All those areas are characterized by relatively short time use. On the other hand, high and very high concentration levels of xenobiotics can be observed, resulting in higher exposure risk. The main compounds or group of chemical compounds are presented and discussed. The main factors influencing the type and amount of chemical pollutants present in the air of such areas are indicated.

  17. A compact proton synchrotron with combined-function lattice dedicated for cancer therapy

    CERN Document Server

    Morita, A; Inoue, M; Shirai, T; Iwashita, Y; Hiramoto, K; Katane, M; Tadokoro, M; Nishi, M; Umezawa, M

    1999-01-01

    A compact proton synchrotron with combined function lattice has been designed as a dedicated machine for cancer therapy because of its merits of easy operation and low construction cost. The lattice has a six-fold symmetry and its radius of curvature and circumference are 1.9 m and 23.9 m, respectively. For the purpose of establishing a good reference design, we have constructed a model magnet based on the three-dimensional magnetic field calculation. A magnetic field measurement has been performed with use of a three-dimensional Hall- probe. In the present paper, the results of these developments is presented together with the outline of the reference design. (3 refs) .

  18. METRIC: A Dedicated Earth-Orbiting Spacecraft for Investigating Gravitational Physics and the Space Environment

    Directory of Open Access Journals (Sweden)

    Roberto Peron

    2017-07-01

    Full Text Available A dedicated mission in low Earth orbit is proposed to test predictions of gravitational interaction theories and to directly measure the atmospheric density in a relevant altitude range, as well as to provide a metrological platform able to tie different space geodesy techniques. The concept foresees a small spacecraft to be placed in a dawn-dusk eccentric orbit between 450 and 1200 km of altitude. The spacecraft will be tracked from the ground with high precision, and a three-axis accelerometer package on-board will measure the non-gravitational accelerations acting on its surface. Estimates of parameters related to fundamental physics and geophysics should be obtained by a precise orbit determination, while the accelerometer data will be instrumental in constraining the atmospheric density. Along with the mission scientific objectives, a conceptual configuration is described together with an analysis of the dynamical environment experienced by the spacecraft and the accelerometer.

  19. Phase aided 3D imaging and modeling: dedicated systems and case studies

    Science.gov (United States)

    Yin, Yongkai; He, Dong; Liu, Zeyi; Liu, Xiaoli; Peng, Xiang

    2014-05-01

    Dedicated prototype systems for 3D imaging and modeling (3DIM) are presented. The 3D imaging systems are based on the principle of phase-aided active stereo, which have been developed in our laboratory over the past few years. The reported 3D imaging prototypes range from single 3D sensor to a kind of optical measurement network composed of multiple node 3D-sensors. To enable these 3D imaging systems, we briefly discuss the corresponding calibration techniques for both single sensor and multi-sensor optical measurement network, allowing good performance of the 3DIM prototype systems in terms of measurement accuracy and repeatability. Furthermore, two case studies including the generation of high quality color model of movable cultural heritage and photo booth from body scanning are presented to demonstrate our approach.

  20. A dedicated program for the extended longevity of research and training reactors

    International Nuclear Information System (INIS)

    Carriveau, G.W.

    1992-01-01

    In the past 49 years, over 555 research and training reactors have been in operation, with approximately 325 currently in service. The age distribution of operating research reactors shows that the average age is about 24 years; about 74% are 20 years old or older and about 33% are 30 years old or older. This group of reactors represents a very large investment in capital expense with replacement costs in 1990's prices much higher than when they were originally constructed. Furthermore, decommissioning costs may be much greater than the original investments. General Atomics has been directly involved for the better part of the nearly fifty year history of research and training reactors. This paper will describe a General Atomics program illustrating a dedicated commitment to the full service support of extended and improved use for all types of research and training reactors. (author)

  1. Comparative study of energy conversion system dedicated to a small wind turbine

    International Nuclear Information System (INIS)

    Mirecki, A.

    2005-01-01

    This study presents a comparison of architectures and strategies of energy management dedicated to VAWT turbines such as Savonius. A Maximum Power Point Tracking must be implemented in order to optimize the energetic behavior. A torque or a speed control, or an indirect control of the DC bus current is possible. In the fact that the wind turbine characteristic is unknown, an operational research based on fuzzy logic is proposed. Aiming to minimize the cost of the static conversion structure, simple structures (diode bridge inverter, associated with DC-DC chopper) are analyzed and compared with a system based on a PWM Voltage Source Inverter. A test bench has been realized in the meantime as a system simulation. Comparisons of the provided energy are made for different wind speeds allowing to evaluate the performance of each structure and of the control strategies. (author)

  2. Detection of small leakage combining dedicated Kalman filters and an extended version of the binary SPRT

    International Nuclear Information System (INIS)

    Racz, A.

    1991-12-01

    A new method is outlined for detection of soft reactor failures. The procedure is applicable when the failure can be described by an additive term (failure vector) in the measurement process of an observable dynamic system. A dedicated Kalman filter generates the innovation process for further testing. The innovation is investigated by a sequential hypothesis testing method. In order to avoid the computational difficulties related to sophisticated multiple hypothesis testing methods, an extended version of Walds's classical binary Sequential Probability Ratio Testing (SPRT) has been developed. The procedure is applied for the problem of (small) leakage detection in the feedwater system of nuclear power plants. Computer simulation results show that the method can recognize less than 1% relative water loss reliably. (author) 10 refs.; 5 figs.; 5 tabs

  3. Towards the creation of an industrial sector dedicated to nuclear dismantling

    International Nuclear Information System (INIS)

    Anon.

    2015-01-01

    In next decades the business of nuclear dismantling is expected to grow exponentially due to the decommissioning of nuclear facilities that will have reached the end of their operating life. Dismantling has 2 main features: dismantling operations on a same site can span decades and dismantling is a new activity in which innovations are likely to appear and may benefit other sectors. In France regional authorities have promoted public-private partnerships in order to make working together small enterprises very specialized in sectors like robotic, laser cutting, waste processing, remote operations... with public laboratories dedicated to nuclear research, and with graduate schools to include dismantling in curriculum and with major industrial operators of the nuclear industry. The aim is the creation of jobs and the building of an industrial sector able to win market shares in the worldwide business of nuclear dismantling. (A.C.)

  4. Factors affecting radiation doses from dedicated rail transport of spent reactor fuel

    International Nuclear Information System (INIS)

    Martin, J.E.

    1988-01-01

    This paper reports there are two exposure control concerns associated with the shipment of spent reactor fuel in dedicated trains -- compliance with transportation regulations for maximum allowable radiation levels, and minimizing the dose received by the general public. This article examines the methods used to calculate the dose equivalent rates alongside stationary (transport regulations) and moving trains (public exposure) of various lengths. The factors examined include the source term, the effect of overlapping radiation fields, the speed of the train, and the location of the population relative to the train. Trains made up of series of cars that individually meet transport regulations can, as a whole, exceed transport vehicle dose equivalent rate limits by up to 23% due to overlapping radiation fields. For moving trains and the worst case analyzed -- a person located 20 feet from the tracks and a train speed of 5 mph --- 141 rail cars would have to pass by to deliver a dose equivalent of 1 mrem

  5. On line filtering of events in an experiment dedicated to the production of massive muon pairs

    International Nuclear Information System (INIS)

    Froberger, J.P.

    1980-07-01

    The NA10 experiment is dedicated to the inclusive production of pairs of massive muons in hadronic collisions, particularly in pion-nucleon collisions. This experiment allows the testing of the Drell-Yan model that describes the production process. The detector is composed of 8 proportional multiwire chambers. This work presents the development of an algorithm able to filter and select adequate events from the data flowing from the detector. Simulations show that the program running on GESPRO system is able to compute the mass of the muon pairs and to take the decision to ban or not the event in less than 20 μs. In the first chapter the author describes the Drell-Yan model. The methodology to analyse data and select adequate events is given in the second chapter. The algorithm is developed in the third chapter and tested with simulations in the fourth chapter. (A.C.)

  6. Reliability study of Piezoelectric Structures Dedicated to Energy Harvesting by the Way of Blocking Force Investigation

    International Nuclear Information System (INIS)

    Maaroufi, S; Parrain, F; Lefeuvre, E; Boutaud, B; Molin, R Dal

    2015-01-01

    In this paper we propose an approach to study the reliability of piezoelectric structures and more precisely energy harvesting micro-devices dedicated to autonomous active medical implants (new generation pacemakers). The structure under test is designed as a bimorph piezoelectric cantilever with a seismic mass at its tip. Good understanding of material aging and mechanical failure is critical for this kind of system. To study the reliability and durability of the piezoelectric part we propose to establish a new accelerated methodology and an associated test bench where the environment and stimuli can be precisely controlled over a wide period of time. This will allow the identification of potential failure modes and the study of their impacts by the way of direct mechanical investigation based on stiffness and blocking force measurements performed periodically. (paper)

  7. Reliability study of Piezoelectric Structures Dedicated to Energy Harvesting by the Way of Blocking Force Investigation

    Science.gov (United States)

    Maaroufi, S.; Parrain, F.; Lefeuvre, E.; Boutaud, B.; Dal Molin, R.

    2015-12-01

    In this paper we propose an approach to study the reliability of piezoelectric structures and more precisely energy harvesting micro-devices dedicated to autonomous active medical implants (new generation pacemakers). The structure under test is designed as a bimorph piezoelectric cantilever with a seismic mass at its tip. Good understanding of material aging and mechanical failure is critical for this kind of system. To study the reliability and durability of the piezoelectric part we propose to establish a new accelerated methodology and an associated test bench where the environment and stimuli can be precisely controlled over a wide period of time. This will allow the identification of potential failure modes and the study of their impacts by the way of direct mechanical investigation based on stiffness and blocking force measurements performed periodically.

  8. Impact of a Dedicated Emergency Medicine Teaching Resident Rotation at a Large Urban Academic Center

    Directory of Open Access Journals (Sweden)

    James Ahn, MD

    2016-03-01

    Full Text Available Introduction: In the face of declining bedside teaching and increasing emergency department (ED crowding, balancing education and patient care is a challenge. Dedicated shifts by teaching residents (TRs in the ED represent an educational intervention to mitigate these difficulties. We aimed to measure the perceived learning and departmental impact created by having TR. Methods: TRs were present in the ED from 12pm-10pm daily, and their primary roles were to provide the following: assist in teaching procedures, give brief “chalk talks,” instruct junior trainees on interesting cases, and answer clinical questions in an evidence-based manner. This observational study included a survey of fourth-year medical students (MSs, residents and faculty at an academic ED. Surveys measured the perceived effect of the TR on teaching, patient flow, ease of procedures, and clinical care. Results: Survey response rates for medical students, residents, and faculty are 56%, 77%, and 75%, respectively. MSs perceived improved procedure performance with TR presence and the majority agreed that the TR was a valuable educational experience. Residents perceived increased patient flow, procedure performance, and MS learning with TR presence. The majority agreed that the TR improved patient care. Faculty agreed that the TR increased resident and MS learning, as well as improved patient care and procedure performance. Conclusion: The presence of a TR increased MS and resident learning, improved patient care and procedure performance as perceived by MSs, residents and faculty. A dedicated TR program can provide a valuable resource in achieving a balance of clinical education and high quality healthcare.

  9. Acting with dedication and expertise: Relatives' experience of nurses' provision of care in a palliative unit.

    Science.gov (United States)

    Grøthe, Å; Biong, Stian; Grov, E K

    2015-12-01

    Admission of a cancer patient to a palliative unit when near the final stage of their disease trajectory undoubtedly impacts their relatives. The aim of our study was to illuminate and interpret relatives' lived experiences of health personnel's provision of care in a palliative ward. A phenomenological/hermeneutic approach was employed that was inspired by the philosophical tradition of Heidegger and Ricoeur and further developed by Lindseth and Nordberg. The perspectives of the narrator and the text were interpreted by highlighting relatives' views on a situation in which they have to face existential challenges. The analysis was undertaken in three steps: naïve reading, structural analysis, and comprehensive understanding, including the authors' professional experiences and theoretical background. Six subthemes appeared: the dying person, the bubble, the sight, the cover, the provision for children's needs, and the availability of immediate help. These components were further constructed into three themes: the meaning of relating, the meaning of action, and the meaning of resources. Our comprehensive understanding of the results suggests that the most important theme is "acting with dedication and expertise." The following aspects are crucial for relatives of cancer patients hospitalized in a palliative ward: time and existence, family dynamics, and care adjusted to the situation. Our study results led to reflections on the impact of how nurses behave when providing care to patients during the palliative phase, and how they interact with relatives in this situation. We found that cancer patients in a palliative unit most appreciate nurses who act with dedication and expertise.

  10. Neutron dynamics of fast-spectrum dedicated cores for waste transmutation

    International Nuclear Information System (INIS)

    Massara, S.

    2002-04-01

    Among different scenarios achieving minor actinide transmutation, the possibility of double strata scenarios with critical, fast spectrum, dedicated cores must be checked and quantified. In these cores, the waste fraction has to be at the highest level compatible with safety requirements during normal operation and transient conditions. As reactivity coefficients are poor in such critical cores (low delayed neutron fraction and Doppler feed-back, high coolant void coefficient), their dynamic behaviour during transient conditions must be carefully analysed. Three nitride-fuel configurations have been analysed: two liquid metal-cooled (sodium and lead) and a particle-fuel helium-cooled one. A dynamic code, MAT4 DYN, has been developed during the PhD thesis, allowing the study of loss of flow, reactivity insertion and loss of coolant accidents, and taking into account two fuel geometries (cylindrical and spherical) and two thermal-hydraulics models for the coolant (incompressible for liquid metals and compressible for helium). Dynamics calculations have shown that if the fuel nature is appropriately chosen (letting a sufficient margin during transients), this can counterbalance the bad state of reactivity coefficients for liquid metal-cooled cores, thus proving the interest of this kind of concept. On the other side, the gas-cooled core dynamics is very badly affected by the high value of the helium void coefficient (which is a consequence of the choice of a hard spectrum), this effect being amplified by the very low thermal inertia of particle-fuel design. So, a new kind of concept should be considered for a helium-cooled fast-spectrum dedicated core. (authors)

  11. Dedicated tool to assess the impact of a rhetorical task on human body temperature.

    Science.gov (United States)

    Koprowski, Robert; Wilczyński, Sławomir; Martowska, Katarzyna; Gołuch, Dominik; Wrocławska-Warchala, Emilia

    2017-10-01

    Functional infrared thermal imaging is a method widely used in medicine, including analysis of the mechanisms related to the effect of emotions on physiological processes. The article shows how the body temperature may change during stress associated with performing a rhetorical task and proposes new parameters useful for dynamic thermal imaging measurements MATERIALS AND METHODS: 29 healthy male subjects were examined. They were given a rhetorical task that induced stress. Analysis and processing of collected body temperature data in a spatial resolution of 256×512pixels and a temperature resolution of 0.1°C enabled to show the dynamics of temperature changes. This analysis was preceded by dedicated image analysis and processing methods RESULTS: The presented dedicated algorithm for image analysis and processing allows for fully automated, reproducible and quantitative assessment of temperature changes and time constants in a sequence of thermal images of the patient. When performing the rhetorical task, the temperature rose by 0.47±0.19°C in 72.41% of the subjects, including 20.69% in whom the temperature decreased by 0.49±0.14°C after 237±141s. For 20.69% of the subjects only a drop in temperature was registered. For the remaining 6.89% of the cases, no temperature changes were registered CONCLUSIONS: The performance of the rhetorical task by the subjects causes body temperature changes. The ambiguous temperature response to the given stress factor indicates the complex mechanisms responsible for regulating stressful situations. Stress associated with the examination itself induces body temperature changes. These changes should always be taken into account in the analysis of infrared data. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. Hypospadias surgery in children: improved service model of enhanced recovery pathway and dedicated surgical team.

    Science.gov (United States)

    Wong, Y S; Pang, K K; Tam, Y H

    2018-05-21

    Children in Hong Kong are generally hospitalised for 1 to 2 weeks after hypospadias repairs. In July 2013, we introduced a new service model that featured an enhanced recovery pathway and a dedicated surgical team responsible for all perioperative services. In this study, we investigated the outcomes of hypospadias repair after the introduction of the new service model. We conducted a retrospective study on consecutive children who underwent primary hypospadias repair from January 2006 to August 2016, comparing patients under the old service with those under the new service. Outcome measures included early morbidity, operative success, and completion of enhanced recovery pathway. The old service and new service cohorts comprised 176 and 126 cases, respectively. There was no difference between the two cohorts in types of hypospadias and surgical procedures performed. The median hospital stay was 2 days in the new service cohort compared with 10 days in the old service cohort (Pservice than the old service. Multivariable analysis revealed that the new service significantly reduced the odds of early morbidity (odds ratio=0.35, 95% confidence interval=0.15-0.85; P=0.02) and operative failure (odds ratio=0.32, 95% confidence interval=0.17-0.59; Pservice. Of the new service cohort, 111(88.1%) patients successfully completed the enhanced recovery pathway. The enhanced recovery pathway can be implemented safely and effectively to primary hypospadias repair. A dedicated surgical team may play an important role in successful implementation of the enhanced recovery pathway and optimisation of surgical outcomes.

  13. The development of a thermoelectric power generator dedicated to stove-fireplaces with heat accumulation systems

    International Nuclear Information System (INIS)

    Sornek, Krzysztof; Filipowicz, Mariusz; Rzepka, Kamila

    2016-01-01

    Highlights: • Application of thermoelectric generators in the stove-fireplace with accumulation. • Construction of the thermoelectric generator is limited by the heat accumulation. • Variants of the heat exchanger’s construction are discussed. • The control method is related on velocity of flue gas and water cooling. • The power limit of 30 W for self-sufficient operation is sufficient. - Abstract: A significant part of the world’s population (about 40%) cooks their meals and provides heating for their homes using wood-burning heating devices. Due to the relatively low cost of fuel and their aesthetic design, solid fuel stoves capable of heat accumulation are convenient and common. The use of dedicated small-scale power generators provides also additional benefits. This paper presents the results of a study conducted to verify the possibility of generating power using stove-fireplaces with heat accumulation systems. In such units, the temperature of the flue gas should be kept at a certain level for the purposes of storing heat, which results from certain limitations of the thermoelectric generators. To verify the possibility of applying thermoelectric modules in such heating devices, a dedicated system with thermoelectric generators was selected from among various microcogeneration systems and implemented. Three types of heat exchangers were studied and the most efficient unit was selected for further testing. Two types of generators, with maximum operating temperatures of 320 and 175 °C, were compared. Subsequently, the characteristics of the latter were determined. The conducted tests allowed to determine the performance and the total efficiency of the generators that were used. It has been demonstrated that the maximum power of the generator would not exceed ca. 30 W e and that there is no economic justification for such a device. However, providing a self-powered and self-sufficient operation of stove-fireplaces with heat accumulation systems

  14. Commissioning and quality control of a dedicated wide bore 3T MRI simulator for radiotherapy planning

    Directory of Open Access Journals (Sweden)

    Aitang Xing

    2016-06-01

    Full Text Available Purpose: The purpose of this paper is to describe a practical approach to commissioning and quality assurance (QA of a dedicated wide-bore 3 Tesla (3T magnetic resonance imaging (MRI scanner for radiotherapy planning.Methods: A comprehensive commissioning protocol focusing on radiotherapy (RT specific requirements was developed and performed. RT specific tests included: uniformity characteristics of radio-frequency (RF coil, couch top attenuation, geometric distortion, laser and couch movement and an end-to-end radiotherapy treatment planning test. General tests for overall system performance and safety measurements were also performed.Results: The use of pre-scan based intensity correction increased the uniformity from 61.7% to 97% (body flexible coil, from 50% to 90% (large flexible coil and from 51% to 98% (small flexible coil. RT flat top couch decreased signal-to-noise ratio (SNR by an average of 42%. The mean and maximum geometric distortion was found to be 1.25 mm and 4.08 mm for three dimensional (3D corrected image acquisition, 2.07 mm and 7.88 mm for two dimensional (2D corrected image acquisition over 500 mm × 375 mm × 252 mm field of view (FOV. The accuracy of the laser and couch movement was less than ±1 mm. The standard deviation of registration parameters for the end-to-end test was less than 0.41 mm. An on-going QA program was developed to monitor the system’s performance.Conclusion: A number of RT specific tests have been described for commissioning and subsequent performance monitoring of a dedicated MRI simulator (MRI-Sim. These tests have been important in establishing and maintaining its operation for RT planning.

  15. Fallopian tube recanalisation using dedicated radiographic tubal assessment set in angiography suite

    International Nuclear Information System (INIS)

    Al-Omari, M.H; Rousan, L.; Al-balas, H.; Alawneh, K.; El-heis, M.; Al-mnayyis, A.; Obeidat, N.; Amarin, Z.; Zayed, F.; Omari, Z.; Hanania, R.

    2014-01-01

    Fallopian tube recanalisation (FTR) for proximal fallopian tube obstruction (PFTO) is considered a good treatment option for tubal infertility. The aim of this study was to assess the safety and the technical and clinical success rates of FTR using a dedicated radiographic tubal assessment set (FluoroSet®) in the angiography suite. This study is a retrospective analysis of data prospectively collected between February 2007 and June 2011 at King Abdullah University Hospital, Irbid, Jordan. During this period, 61 patients affected by PFTO underwent FTR using FluoroSet® at our institution. The mean age of patients was 34 years (range 20-45 years), and the mean duration of infertility was 4 years (range 2-14 years). The procedure was performed with conscious sedation under fluoroscopic guidance in the angiography suite. The obstructed tube was accessed with a 5-Fr multipurpose catheter, and the obstruction was crossed with a 0.35-Fr hydrophilic guide wire until the wire coiled freely into the peritoneal cavity. Patency of the tube was then confirmed by selective salpingiogram. Technical success rate was recorded, and patients were followed up for evidence of pregnancy over 12 months. The procedure was technically successful in all patients. Minor bleeding and postprocedural pain occurred in most patients; however, there were no major complications encountered. Twenty-five patients (41%) became pregnant. Successful deliveries of full-term infants were reported in 21 patients (84%). Miscarriage was reported in four patients (16%). No ectopic pregnancies were detected, and all deliveries were full-term. The technical success rate was 100% and the clinical success rate was 41%. Selective salpingography and FTR using FluoroSet® is a safe and effective method. FTR is recommended as the first intervention in patients with PFTO. In experienced hands with dedicated equipment and in an appropriate setting, the success rate is high, and this treatment should be offered to

  16. Quality of pediatric abdominal CT scans performed at a dedicated children's hospital and its referring institutions: a multifactorial evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Snow, Aisling [Boston Children' s Hospital, Department of Radiology, Boston, MA (United States); Our Lady' s Children' s Hospital, Department of Radiology, Dublin (Ireland); Milliren, Carly E.; Graham, Dionne A. [Boston Children' s Hospital, Program for Patient Safety and Quality, Boston, MA (United States); Callahan, Michael J.; MacDougall, Robert D.; Robertson, Richard L.; Taylor, George A. [Boston Children' s Hospital, Department of Radiology, Boston, MA (United States)

    2017-04-15

    Pediatric patients requiring transfer to a dedicated children's hospital from an outside institution may undergo CT imaging as part of their evaluation. Whether this imaging is performed prior to or after transfer has been shown to impact the radiation dose imparted to the patient. Other quality variables could also be affected by the pediatric experience and expertise of the scanning institution. To identify differences in quality between abdominal CT scans and reports performed at a dedicated children's hospital, and those performed at referring institutions. Fifty consecutive pediatric abdominal CT scans performed at outside institutions were matched (for age, gender and indication) with 50 CT scans performed at a dedicated freestanding children's hospital. We analyzed the scans for technical parameters, report findings, correlation with final clinical diagnosis, and clinical utility. Technical evaluation included use of intravenous and oral contrast agents, anatomical coverage, number of scan phases and size-specific dose estimate (SSDE) for each scan. Outside institution scans were re-reported when the child was admitted to the children's hospital; they were also re-interpreted for this study by children's hospital radiologists who were provided with only the referral information given in the outside institution's report. Anonymized original outside institutional reports and children's hospital admission re-reports were analyzed by two emergency medicine physicians for ease of understanding, degree to which the clinical question was answered, and level of confidence in the report. Mean SSDE was lower (8.68) for children's hospital scans, as compared to outside institution scans (13.29, P = 0.03). Concordance with final clinical diagnosis was significantly lower for original outside institution reports (38/48, 79%) than for both the admission and study children's hospital reports (48/50, 96%; P = 0.005). Children

  17. Health care professionals' experience, understanding and perception of need of advanced cancer patients with cachexia and their families: The benefits of a dedicated clinic.

    Science.gov (United States)

    Scott, David; Reid, Joanne; Hudson, Peter; Martin, Peter; Porter, Sam

    2016-12-30

    Cachexia is defined as the on-going loss of skeletal muscle mass that cannot be fully reversed by conventional nutritional support. It is found in up to 80% of patients with advanced cancer and has profound psycho-social consequences for patients and their families. Previous studies demonstrate that many healthcare professionals receive little formal education in cachexia management leading them to feel that they have limited understanding of the syndrome and cannot intervene effectively. This study aims to examine the value of a dedicated cachexia clinic and its influence on staff understanding and practice. An exploratory qualitative study was conducted. The study employed semi-structured interviews with a range of healthcare professionals responsible for designing and delivering cancer care in a large teaching hospital in Australia. This hospital had a dedicated cachexia clinic. In-depth interviews were conducted with 8 healthcare professionals and senior managers. Four themes were identified: formal and informal education; knowledge and understanding; truth telling in cachexia and palliative care; and, a multi-disciplinary approach. Findings show that improved knowledge and understanding across a staff body can lead to enhanced staff confidence and a willingness to address cancer cachexia and its consequences with patients and their families. Comparisons with similar previous research demonstrate the advantages of providing a structure for staff to gain knowledge about cachexia and how this can contribute to feelings of improved understanding and confidence necessary to respond to the challenge of cachexia.

  18. Environmental information systems based on enterprise resource planning. Selected papers of 3rd international symposium on logistics, Padua, Italia, 1997

    NARCIS (Netherlands)

    Lambert, A.J.D.; Jansen-Vullers, M.H.; Splinter, M.A.M.

    2000-01-01

    This paper describes the consequences of the integration of environmental information within enterprise resource planning (ERP) systems. The state-of-the art of dedicated environmental information systems is briefly discussed. Essentials and peculiarities of environmental information are

  19. Quantitatively accurate activity measurements with a dedicated cardiac SPECT camera: Physical phantom experiments

    Energy Technology Data Exchange (ETDEWEB)

    Pourmoghaddas, Amir, E-mail: apour@ottawaheart.ca; Wells, R. Glenn [Physics Department, Carleton University, Ottawa, Ontario K1S 5B6, Canada and Cardiology, The University of Ottawa Heart Institute, Ottawa, Ontario K1Y4W7 (Canada)

    2016-01-15

    Purpose: Recently, there has been increased interest in dedicated cardiac single photon emission computed tomography (SPECT) scanners with pinhole collimation and improved detector technology due to their improved count sensitivity and resolution over traditional parallel-hole cameras. With traditional cameras, energy-based approaches are often used in the clinic for scatter compensation because they are fast and easily implemented. Some of the cardiac cameras use cadmium-zinc-telluride (CZT) detectors which can complicate the use of energy-based scatter correction (SC) due to the low-energy tail—an increased number of unscattered photons detected with reduced energy. Modified energy-based scatter correction methods can be implemented, but their level of accuracy is unclear. In this study, the authors validated by physical phantom experiments the quantitative accuracy and reproducibility of easily implemented correction techniques applied to {sup 99m}Tc myocardial imaging with a CZT-detector-based gamma camera with multiple heads, each with a single-pinhole collimator. Methods: Activity in the cardiac compartment of an Anthropomorphic Torso phantom (Data Spectrum Corporation) was measured through 15 {sup 99m}Tc-SPECT acquisitions. The ratio of activity concentrations in organ compartments resembled a clinical {sup 99m}Tc-sestamibi scan and was kept consistent across all experiments (1.2:1 heart to liver and 1.5:1 heart to lung). Two background activity levels were considered: no activity (cold) and an activity concentration 1/10th of the heart (hot). A plastic “lesion” was placed inside of the septal wall of the myocardial insert to simulate the presence of a region without tracer uptake and contrast in this lesion was calculated for all images. The true net activity in each compartment was measured with a dose calibrator (CRC-25R, Capintec, Inc.). A 10 min SPECT image was acquired using a dedicated cardiac camera with CZT detectors (Discovery NM530c, GE

  20. CT arthrography of the wrist using a novel, mobile, dedicated extremity cone-beam CT (CBCT)

    Energy Technology Data Exchange (ETDEWEB)

    Koskinen, Seppo K. [Helsinki University Central Hospital, Department of Radiology, HUS Helsinki Medical Imaging Center, Helsinki (Finland); Helsinki University Hospital, Toeoeloe Trauma Center, Department of Radiology, HUS Helsinki Medical Imaging Center, Helsinki (Finland); Haapamaeki, Ville V.; Kortesniemi, Mika [Helsinki University Central Hospital, Department of Radiology, HUS Helsinki Medical Imaging Center, Helsinki (Finland); Salo, Jari [Helsinki University Central Hospital, Department of Orthopedic and Trauma Surgery, Helsinki (Finland); Kuopio University Hospital, UEF, Department of Orthopedics, Traumatology and Hand Surgery, Kuopio (Finland); Lindfors, Nina C. [Helsinki University Central Hospital, Department of Orthopedic and Hand Surgery, Helsinki (Finland); Seppaelae, Lauri [Planmed Oy, Helsinki (Finland); Mattila, Kimmo T. [Turku University Central Hospital, Department of Diagnostic Radiology, Turku (Finland)

    2013-05-15

    To evaluate the feasibility and intra- and interobserver agreement of CBCT arthrography of wrist ligaments, triangular fibrocartilaginous complex (TFCC), and to assess the sensitivity (SE), specificity (SP), accuracy (ACC), and positive and negative predictive value (PPV, NPV) of CBCT arthrography in the diagnosis of scapholunate (SLL) and lunotriquetral (LTL) ligament tears, TFCC, and cartilage abnormalities of the scaphoid and lunate with their corresponding radial surfaces (scaphoid and lunate fossa) using a novel, mobile, dedicated extremity CBCT scanner. Fifty-two consecutively enrolled subjects (26 M, 26 F, mean age 38 years, range 18-66 years) with suspected wrist ligament tears underwent CBCT-arthrography before normally scheduled MR arthrography.An extremity CBCT was used for imaging with isotropic voxel size of 0.4 x 0.4 x 0.4 mm{sup 3}. Subsequent routine 1.5 T MRI was performed using a dedicated wrist coil.Two observers reviewed the anonymized CBCT images twice for contrast enhancement (CE) and technical details (TD), for tears of the SLL, LTL, and TFCC. Also, cartilage abnormalities of the scaphoid and lunate with their corresponding radial surfaces (scaphoid and lunate fossa) were evaluated. Inter- and intraobserver agreement was determined using weighted kappa statistics. Since no surgery was performed, MRI served as a reference standard, and SE and SP, ACC, PPV, and NPV were calculated. Intra- and interobserver kappa values for both readers (reader 1/reader 2; first reading/second reading) with 95 % confidence limits were: CE 0.54 (0.08-1.00)/ 0.75 (0.46-1.00); 0.73 (0.29-1.00)/ 0.45 (0.07-0.83), TD 0.53 (0.30-0.88)/ 0.86 (0.60-1.00); 0.56 (0.22-0.91)/ 0.67 (0.37-0.98), SLL 0.59 (0.25-0.93)/ 0.66 (0.42-0.91); 0.31 (0.06-0.56)/ 0.49 (0.26-0.73), LTL 0.83 (0.66-1.00)/ 0.68 (0.46-0.91); 0.90 (0.79-1.00)/ 0.48 (0.22-0.74); TFCC (0.72-1.00)/ (0.79-1.00); 0.65 (0.43-0.87)/ 0.59 (0.35-0.83), radius (scaphoid fossa) 0.45 (0.12-0.77)/ 0.64 (0.31-0.96); 0

  1. A miniature TDCR system dedicated to in-situ activity assay.

    Science.gov (United States)

    Johansson, Lena; Bakhshandeiar, Eleanor; Pearce, Andy; Collins, Sean; Orlandini, Pascal; Sephton, John

    2014-05-01

    In the framework of the European Metrology Research Programme (EMRP), the Joint Research Project MetroFission has a dedicated work package for the development of a portable Triple-to-Double-Coincidence-Ratio (TDCR) system dedicated to in-situ activity measurements of low-energy beta emitters arising from the operation of the next generation of nuclear power plants. In the design phase of the NPL version of the mini-TDCR, a wide range of metrological aspects and detector types was considered. This paper summarizes these aspects of design, in the light of previous experience with the primary TDCR system at NPL. For example, in this miniature version of the TDCR, the optical chamber was simplified and cylindrical geometry was deemed sufficient. The reflectivity of the surface was increased by painted layers of Spectraflect(®), a specially formulated barium sulphate coating with high reflectivity across a wide range of wave lengths including UV. This option was chosen rather than the high performing and more expensive Spectralon(®) material used for the primary NPL TDCR. The miniature TDCR system is intended for on-site monitoring and will not require as high a performance as the primary system. Other factors that were considered included sample changing, light tightness, type of photo detector, method for varying the detection efficiency, shielding and the possible addition of an internal gamma-ray source for determination of the quench parameter of the source. In this version, the sample changing is performed using a piston and an automatic shutter. Significant design effort has been applied to ensure minimal ingress of light from the piston. Efficiency variation is accomplished by increasing the vertical displacement of the vial. Provision has been made to automate this at a later stage. Maximum light transmission to the photo-multiplier tubes is obtained at the "zero" reference height. Validation measurements were successfully performed using four different

  2. TU-CD-207-11: Patient-Driven Automatic Exposure Control for Dedicated Breast CT

    International Nuclear Information System (INIS)

    Hernandez, A; Gazi, P; Seibert, J; Boone, J

    2015-01-01

    Purpose: To implement automatic exposure control (AEC) in dedicated breast CT (bCT) on a patient-specific basis using only the pre-scan scout views. Methods: Using a large cohort (N=153) of bCT data sets, the breast effective diameter (D) and width in orthogonal planes (Wa,Wb) were calculated from the reconstructed bCT image and pre-scan scout views, respectively. D, Wa, and Wb were measured at the breast center-of-mass (COM), making use of the known geometry of our bCT system. These data were then fit to a second-order polynomial “D=F(Wa,Wb)” in a least squares sense in order to provide a functional form for determining the breast diameter. The coefficient of determination (R 2 ) and mean percent error between the measured breast diameter and fit breast diameter were used to evaluate the overall robustness of the polynomial fit. Lastly, previously-reported bCT technique factors derived from Monte Carlo simulations were used to determine the tube current required for each breast diameter in order to match two-view mammographic dose levels. Results: F(Wa,Wb) provided fitted breast diameters in agreement with the measured breast diameters resulting in R 2 values ranging from 0.908 to 0.929 and mean percent errors ranging from 3.2% to 3.7%. For all 153 bCT data sets used in this study, the fitted breast diameters ranged from 7.9 cm to 15.7 cm corresponding to tube current values ranging from 0.6 mA to 4.9 mA in order to deliver the same dose as two-view mammography in a 50% glandular breast with a 80 kV x-ray beam and 16.6 second scan time. Conclusion: The present work provides a robust framework for AEC in dedicated bCT using only the width measurements derived from the two orthogonal pre-scan scout views. Future work will investigate how these automatically chosen exposure levels affect the quality of the reconstructed image

  3. Dedicated breast CT: radiation dose for circle-plus-line trajectory

    International Nuclear Information System (INIS)

    Vedantham, Srinivasan; Shi, Linxi; Karellas, Andrew; Noo, Frederic

    2012-01-01

    Purpose: Dedicated breast CT prototypes used in clinical investigations utilize single circular source trajectory and cone-beam geometry with flat-panel detectors that do not satisfy data-sufficiency conditions and could lead to cone beam artifacts. Hence, this work investigated the glandular dose characteristics of a circle-plus-line trajectory that fulfills data-sufficiency conditions for image reconstruction in dedicated breast CT. Methods: Monte Carlo-based computer simulations were performed using the GEANT4 toolkit and was validated with previously reported normalized glandular dose coefficients for one prototype breast CT system. Upon validation, Monte Carlo simulations were performed to determine the normalized glandular dose coefficients as a function of x-ray source position along the line scan. The source-to-axis of rotation distance and the source-to-detector distance were maintained constant at 65 and 100 cm, respectively, in all simulations. The ratio of the normalized glandular dose coefficient at each source position along the line scan to that for the circular scan, defined as relative normalized glandular dose coefficient (RD g N), was studied by varying the diameter of the breast at the chest wall, chest-wall to nipple distance, skin thickness, x-ray beam energy, and glandular fraction of the breast. Results: The RD g N metric when stated as a function of source position along the line scan, relative to the maximum length of line scan needed for data sufficiency, was found to be minimally dependent on breast diameter, chest-wall to nipple distance, skin thickness, glandular fraction, and x-ray photon energy. This observation facilitates easy estimation of the average glandular dose of the line scan. Polynomial fit equations for computing the RD g N and hence the average glandular dose are provided. Conclusions: For a breast CT system that acquires 300-500 projections over 2π for the circular scan, the addition of a line trajectory with equal

  4. Evaluating the use heat pipe for dedicated ventilation of office buildings in Hong Kong

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Lian [Department of Building Services Engineering, Hong Kong Polytechnic University, Hung Hom (Hong Kong); Lee, W.L., E-mail: bewll@polyu.edu.h [Department of Building Services Engineering, Hong Kong Polytechnic University, Hung Hom (Hong Kong)

    2011-04-15

    Research highlights: {yields} Heat pipe dedicated for outdoor air treatment (HPDV system) was investigated. {yields} Investigations were based on cooling demand of 10 existing office buildings in HK. {yields} HPDV system could save energy use for 70% of the air-conditioned hours. {yields} HPDV system could save 1.2% to 7.9% of annual energy use for air-conditioning. {yields} Heat pipe of 57% effectiveness is the best in achieving energy saving objectives. -- Abstract: Recent research studies advocates decoupling dehumidification from cooling to improve indoor air quality and reduce energy consumption. The feasible use of heat pipe at the air handler dedicated for outdoor air treatment (HPDV system) in accomplishing this objective is investigated in this study. To evaluate the performance and the energy saving potential of the proposed HPDV system, the design parameters of 75 Grade A office buildings in Hong Kong were collected. Ten representative buildings were subsequently identified for further study to achieve a confidence level of 95%. The annual cooling load profiles of the 10 representative buildings were simulated by the use of HTB2. Based on the realistic cooling load profiles and the heat pipes of effectiveness 0.35-0.6, the proposed HPDV system in achieving the intended objectives were evaluated. It was found that the savings for the 10 representative buildings were comparable. The reduction in cooling and reheating energy was between 23 and 44 kWh/m{sup 2}, which corresponds to 1.2% and 7.9% saving in annual energy use for air-conditioning. The results indicate that HP of different effectiveness can be applied to save energy for over 70% of the air-conditioned hours; of which only 0.03-6.3% of the time the decoupling objective cannot be achieved (abbreviated as NHRS). Based on the results of the study, a simplified model relating NHRS with heat pipe effectiveness has been established. The model can help designers more quickly determine how NHRS can be

  5. Reducing radiation dose to the female breast during conventional and dedicated breast computed tomography

    Science.gov (United States)

    Rupcich, Franco John

    The purpose of this study was to quantify the effectiveness of techniques intended to reduce dose to the breast during CT coronary angiography (CTCA) scans with respect to task-based image quality, and to evaluate the effectiveness of optimal energy weighting in improving contrast-to-noise ratio (CNR), and thus the potential for reducing breast dose, during energy-resolved dedicated breast CT. A database quantifying organ dose for several radiosensitive organs irradiated during CTCA, including the breast, was generated using Monte Carlo simulations. This database facilitates estimation of organ-specific dose deposited during CTCA protocols using arbitrary x-ray spectra or tube-current modulation schemes without the need to run Monte Carlo simulations. The database was used to estimate breast dose for simulated CT images acquired for a reference protocol and five protocols intended to reduce breast dose. For each protocol, the performance of two tasks (detection of signals with unknown locations) was compared over a range of breast dose levels using a task-based, signal-detectability metric: the estimator of the area under the exponential free-response relative operating characteristic curve, AFE. For large-diameter/medium-contrast signals, when maintaining equivalent AFE, the 80 kV partial, 80 kV, 120 kV partial, and 120 kV tube-current modulated protocols reduced breast dose by 85%, 81%, 18%, and 6%, respectively, while the shielded protocol increased breast dose by 68%. Results for the small-diameter/high-contrast signal followed similar trends, but with smaller magnitude of the percent changes in dose. The 80 kV protocols demonstrated the greatest reduction to breast dose, however, the subsequent increase in noise may be clinically unacceptable. Tube output for these protocols can be adjusted to achieve more desirable noise levels with lesser dose reduction. The improvement in CNR of optimally projection-based and image-based weighted images relative to photon

  6. TU-F-18C-07: Hardware Advances for MTF Improvement in Dedicated Breast CT

    International Nuclear Information System (INIS)

    Gazi, P; Burkett, G; Yang, K; Boone, J

    2014-01-01

    Purpose: In this study, we have designed and implemented a prototype dedicated breast CT system (bCT) to improve the spatial resolution characteristics, in order to improve detection of micro-calcifications. Methods: A 10.8 kW water-cooled, tungsten anode x-ray tube, running up to 240 mA at 60 kV, coupled with an x-ray generator specifically designed for this application, and 0.3 mm of added copper filter was used to generate x-ray pulses. A CsI CMOS flat panel detector with a pixel pitch of 0.075 mm in native binning mode was used. The system geometry was designed in a way to achieve an FOV on par with similar bCT prototypes, resulting in a magnification factor of 1.39. A 0.013 mm tungsten wire was used to generate point spread functions. Multiple scans were performed with different numbers of projections, different reconstruction kernel sizes and different reconstruction filters to study the effects of each parameter on MTF. The resulting MTFs were then evaluated quantitatively using the generated PFSs. Duplicate scans with the same parameters were performed on two other dedicated breast CT systems to compare the performance of the new prototype. Results: The results of the MTF experiments demonstrate a significant improvement in the spatial resolution characteristics. In the new prototype, using the pulsed x-ray source results in a restoration of the azimuthal MTF degradation, due to motion blurring previously seen in other bCT systems. Moreover, employing the higher resolution x-ray detector considerably improves the MTF. The MTF at 10% of the new system is at 3.5 1/mm, a factor of 4.36 greater than an earlier bCT scanner. Conclusion: The MTF analysis of the new prototype bCT shows that using the new hardware and control results in a significant improvement in visualization of finer detail. This suggests that the visualization of micro-calcifications will be significantly improved

  7. TU-CD-207-11: Patient-Driven Automatic Exposure Control for Dedicated Breast CT

    Energy Technology Data Exchange (ETDEWEB)

    Hernandez, A; Gazi, P [Biomedical Engineering Graduate Group, University of California Davis, Davis, CA (United States); Department of Radiology, UC Davis Medical Center, Sacramento, CA (United States); Seibert, J; Boone, J [Department of Radiology, UC Davis Medical Center, Sacramento, CA (United States); Department of Biomedical Engineering, University of California Davis, Davis, CA (United States)

    2015-06-15

    Purpose: To implement automatic exposure control (AEC) in dedicated breast CT (bCT) on a patient-specific basis using only the pre-scan scout views. Methods: Using a large cohort (N=153) of bCT data sets, the breast effective diameter (D) and width in orthogonal planes (Wa,Wb) were calculated from the reconstructed bCT image and pre-scan scout views, respectively. D, Wa, and Wb were measured at the breast center-of-mass (COM), making use of the known geometry of our bCT system. These data were then fit to a second-order polynomial “D=F(Wa,Wb)” in a least squares sense in order to provide a functional form for determining the breast diameter. The coefficient of determination (R{sup 2}) and mean percent error between the measured breast diameter and fit breast diameter were used to evaluate the overall robustness of the polynomial fit. Lastly, previously-reported bCT technique factors derived from Monte Carlo simulations were used to determine the tube current required for each breast diameter in order to match two-view mammographic dose levels. Results: F(Wa,Wb) provided fitted breast diameters in agreement with the measured breast diameters resulting in R{sup 2} values ranging from 0.908 to 0.929 and mean percent errors ranging from 3.2% to 3.7%. For all 153 bCT data sets used in this study, the fitted breast diameters ranged from 7.9 cm to 15.7 cm corresponding to tube current values ranging from 0.6 mA to 4.9 mA in order to deliver the same dose as two-view mammography in a 50% glandular breast with a 80 kV x-ray beam and 16.6 second scan time. Conclusion: The present work provides a robust framework for AEC in dedicated bCT using only the width measurements derived from the two orthogonal pre-scan scout views. Future work will investigate how these automatically chosen exposure levels affect the quality of the reconstructed image.

  8. Critical Characteristics of Radiation Detection System Components to be Dedicated for use in Safety Class and Safety Significant System

    International Nuclear Information System (INIS)

    DAVIS, S.J.

    2000-01-01

    This document identifies critical characteristics of components to be dedicated for use in Safety Significant (SS) Systems, Structures, or Components (SSCs). This document identifies the requirements for the components of the common, radiation area, monitor alarm in the WESF pool cell. These are procured as Commercial Grade Items (CGI), with the qualification testing and formal dedication to be performed at the Waste Encapsulation Storage Facility (WESF) for use in safety significant systems. System modifications are to be performed in accordance with the approved design. Components for this change are commercially available and interchangeable with the existing alarm configuration This document focuses on the operational requirements for alarm, declaration of the safety classification, identification of critical characteristics, and interpretation of requirements for procurement. Critical characteristics are identified herein and must be verified, followed by formal dedication, prior to the components being used in safety related applications

  9. An evaluation of the level of satisfaction with a dedicated inpatient venepuncture service at a rehabilitation centre.

    Science.gov (United States)

    Oatey, Anthea; Stiller, Kathy

    2009-12-01

    The purpose of this prospective observational study was to determine the levels of satisfaction of the three main 'customers' of a dedicated inpatient venepuncture service at a rehabilitation centre, namely the patients, medical staff and nursing staff. The venepuncture service was delivered by two part-time nurses. One hundred and six patients, 14 medical staff and 35 nurses participated in the study. Three purpose-designed surveys were administered to investigate levels of satisfaction. High degrees of satisfaction were reported by all three 'customer' groups. Patients were highly satisfied with the interpersonal skills of the venepuncture nurses and their ability to obtain blood on the first pass, medical staff agreed that a dedicated venepuncture service gave them more time to spend in patient care, and nursing staff believed that a dedicated venepuncture service caused less disruption to patients' daily schedule.

  10. Dedicated Caravan Sites for French Gens du Voyage: Public Health Policy or Construction of Health and Environmental Inequalities?

    Science.gov (United States)

    Foisneau, Lise

    2017-12-01

    In France, gens du voyage ("people who travel" or "travellers") is a term used by the government to categorize various itinerant populations, the majority of which are diverse Romani groups. People categorized as gens du voyage are legally required to reside in particular locations called "dedicated caravan sites." Parliamentary debates about these dedicated caravan sites have clarified that one of the objectives of such sites is to help fulfill the gens du voyage 's right to health. However, there is a significant gap between the officially stated goals of such sites and the reality of life within them. This paper draws on research finding that the conditions in most dedicated caravan sites do not conform with the rights of gens du voyage to acceptable sanitary conditions and other underlying determinants of health.

  11. Interactive Information Retrieval:

    DEFF Research Database (Denmark)

    Borlund, Pia

    IIR from the perspective of search dedication and task load in order to also include everyday life information seeking? With this presentation, the IIR community is invited to an exchange of ideas and is encouraged to engage in collaborations with the solving of these (and other) issues to our joint......This presentation addresses methodological issues of interactive information retrieval (IIR) evaluation in terms of what it entails to study users' use and interaction with IR systems, as well as their satisfaction with retrieved information. In particular, the presentation focuses on test design...... of the users to ensure a complete and realistic picture to enhance our understanding of IIR. The presentation also reflects on whether a re-thinking of the concept on an information need is necessary. One may ask whether it still makes sense to talk about types of information needs. Or should we rather study...

  12. Study of the personal radiation dose received by nuclear medicine technologists working in a dedicated PET centre

    International Nuclear Information System (INIS)

    Robinson, C.N.; Wallace, A.B.; Young, A.B.; Ibbetson, V.J.

    2005-01-01

    The use of dedicated PET scanners is becoming more widespread throughout Australia and the world. PET imaging utilises short-lived (-108 min), high-energy (511 keV) gamma-ray emitters, that could result in a high radiation dose being received by staff. As part of a larger staff and area monitoring project, this paper discusses the personal dose equivalent, H p (10), received by PET staff working in a dedicated PET centre. The typical H (10) received by staff was approximately 31 μSv. The average daily administered activity to patients at Austin Health was 1280 MBq

  13. IXPE: The Imaging X-ray Polarimetry Explorer, Implementing a Dedicated Polarimetry Mission

    Science.gov (United States)

    Ramsey, Brian

    2014-01-01

    Only a few experiments have conducted x-ray polarimetry of cosmic sources since Weisskopf et al confirmed the 19% polarization of the Crab Nebula with the Orbiting Solar Observatory (OSO-8) in the 70's center dot The challenge is to measure a faint polarized component against a background of non-polarized signal (as well as the other, typical background components) center dot Typically, for a few % minimum detectable polarization, 106 photons are required. center dot So, a dedicated mission is vital with instruments that are designed specifically to measure polarization (with minimal systematic effects) Over the proposed mission life (2- 3 years), IXPE will first survey representative samples of several categories of targets: magnetars, isolated pulsars, pulsar wind nebula and supernova remnants, microquasars, active galaxies etc. The survey results will guide detailed follow-up observations. Precise calibration of IXPE is vital to ensuring sensitivity goals are met. The detectors will be characterized in Italy, and then a full calibration of the complete instrument will be performed at MSFC's stray light facility. Polarized flux at different energies Heritage: X-ray Optics at MSFC polarimetry mission.

  14. Development and validation of a simulation tool dedicated to eddy current non destructive testing of tubes

    International Nuclear Information System (INIS)

    Reboud, Ch.

    2006-09-01

    Eddy current testing (ECT) technique is widely used in industrial fields such as iron and steel industry. Dedicated simulation tools provide a great assistance for the optimisation of ECT processes. CEA and the Vallourec Research Center have collaborated in order to develop a simulation tool of ECT of tubes. The volume integral method has been chosen for the resolution of Maxwell equations in a stratified medium, in order to get accurate results with a computation time short enough to carry out optimisation or inversion procedures. A fast model has been developed for the simulation of ECT of non magnetic tubes using specific external probes. New flaw geometries have been modelled: holes and notches with flat bottom. Validations of the developments, which have been integrated to the CIVA platform, have been carried out using experimental data recorded in laboratory conditions and in. industrial conditions, successively. The integral equations derived are solved using the Galerkin variant of the method of moments with pulse functions as projection functions. In order to overcome some memory limitations, other projection functions have been considered. A new discretization scheme based on non-uniform B-Splines of degree 1 or 2 has been implemented, which constitutes an original contribution to the existing literature. The decrease of the mesh size needed to get a given accuracy on the result may lead to the simulation of more complex ECT configurations. (author)

  15. Iterative reconstruction using a Monte Carlo based system transfer matrix for dedicated breast positron emission tomography

    Energy Technology Data Exchange (ETDEWEB)

    Saha, Krishnendu [Ohio Medical Physics Consulting, Dublin, Ohio 43017 (United States); Straus, Kenneth J.; Glick, Stephen J. [Department of Radiology, University of Massachusetts Medical School, Worcester, Massachusetts 01655 (United States); Chen, Yu. [Department of Radiation Oncology, Columbia University, New York, New York 10032 (United States)

    2014-08-28

    To maximize sensitivity, it is desirable that ring Positron Emission Tomography (PET) systems dedicated for imaging the breast have a small bore. Unfortunately, due to parallax error this causes substantial degradation in spatial resolution for objects near the periphery of the breast. In this work, a framework for computing and incorporating an accurate system matrix into iterative reconstruction is presented in an effort to reduce spatial resolution degradation towards the periphery of the breast. The GATE Monte Carlo Simulation software was utilized to accurately model the system matrix for a breast PET system. A strategy for increasing the count statistics in the system matrix computation and for reducing the system element storage space was used by calculating only a subset of matrix elements and then estimating the rest of the elements by using the geometric symmetry of the cylindrical scanner. To implement this strategy, polar voxel basis functions were used to represent the object, resulting in a block-circulant system matrix. Simulation studies using a breast PET scanner model with ring geometry demonstrated improved contrast at 45% reduced noise level and 1.5 to 3 times resolution performance improvement when compared to MLEM reconstruction using a simple line-integral model. The GATE based system matrix reconstruction technique promises to improve resolution and noise performance and reduce image distortion at FOV periphery compared to line-integral based system matrix reconstruction.

  16. Analytical calculation of central-axis dosimetric data for a dedicated 6-MV radiosurgery linear accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Yang, James N.; Pino, Ramiro [Department of Radiation Physics, Unit 94, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030 (United States); Department of Radiology, Baylor College of Medicine and Methodist Hospital, Houston, Texas 77030 (United States)

    2008-10-15

    Narrow beams are extensively used in stereotactic radiosurgery. The accuracy of treatment planning dose calculation depends largely on how well the dosimetric data are measured during the machine commissioning. Narrow beams are characterized by the lack of lateral electronic equilibrium. The lateral electronic disequilibrium in the radiation field and detector's finite size are likely to compromise the accuracy in dose measurements in these beams. This may have a profound impact on outcome in patients who undergo stereotactic radiosurgery. To confirm the measured commissioning data for a dedicated 6-MV linear accelerator-based radiosurgery system, we developed an analytical model to calculate the narrow photon beam central-axis dose. This model is an extension of a previously reported method of Nizin and Mooij for the calculation of the absorbed dose under lateral electronic disequilibrium conditions at depth of d{sub max} or greater. The scatter factor and tissue-maximum ratio were calculated for narrow beams using the parametrized model and compared to carefully measured results for the same beams. For narrow beam radii ranging from 0.2 to 1.5 cm, the differences between the analytical and measured scatter factors were no greater than 1.4%. In addition, the differences between the analytical and measured tissue-maximum ratios were within 3.3% for regions greater than the maximum dose depth. The estimated error of this analytical calculation was less than 2%, which is sufficient to validate measurement results.

  17. Impact of a dedicated infusion clinic for acute management of adults with sickle cell pain crisis.

    Science.gov (United States)

    Lanzkron, Sophie; Carroll, C Patrick; Hill, Peter; David, Mandy; Paul, Nicklaine; Haywood, Carlton

    2015-05-01

    Most adults with sickle cell disease (SCD) receive care for their acute painful episodes in an emergency department (ED) setting. The purpose of this article is to describe the impact of opening a dedicated treatment center for adults with SCD [Sickle Cell Infusion Clinic (SCIC)] on patient outcomes and on hospital discharges for SCD. Descriptive data including demographics, time to first dose of narcotic, and pain scores were collected on patients presenting to the SCIC and ED. Maryland hospital discharge data were obtained from the Maryland Health Services Cost Review Commission. Analyses were conducted using T tests, χ(2) tests, and simple generalized estimating equation regression models accounting for the clustered nature of observations, as appropriate. There were 3,874 visits to the SCIC by 361 unique patients; 85% of those visits resulted in the patient being sent home. During the same time period, there were 3,408 visits to the ED by 558 unique patients with SCD. The overall admission rate from the ED for these patients was 35.9% but decreased significantly over the time period with a rate of 20% in December 2011. There was a significant decrease in readmissions over time for the entire Baltimore Metro area with the likelihood of readmission decreasing by 7% over time. The SCIC model provides adults with SCD access to high quality care that decreases the need for hospital admission. Further research needs to be done to evaluate the cost effectiveness of this model. © 2015 Wiley Periodicals, Inc.

  18. Performance analysis of dedicated short range communications technology and overview of the practicability for developing countries

    Directory of Open Access Journals (Sweden)

    Vandana Bassoo

    2015-12-01

    Full Text Available Vehicular communication is a widely researched field and aims at developing technologies that may complement systems such as the advanced driver assistance systems. It is therefore important to analyse and infer on the performance of vehicular technologies for different driving and on-road criteria. This study considers the dedicated short range communications technology and more precisely the IEEE 802.11p standard for a performance and practicability analysis. There is also the proposal of a new classification scheme for typical driving conditions, which includes the main categories of Emergency and Safety scenarios while sub-classifications of Critical and Preventive Safety also exist. The scheme is used to build up scenarios as well as related equations relevant to developing countries for practical network simulation. The results obtained indicate that the relative speed of nodes is a determining factor in the overall performance and effectiveness of wireless vehicular communication systems. Moreover, delay values of low order were observed while an effective communication range of about 800 m was calculated for highway scenarios. The research thus indicates suitability of the system for an active use in collision avoidance even though independent factors such as climatic conditions and driver behaviour may affect its effectiveness in critical situations.

  19. YBCO hot-electron bolometers dedicated to THz detection and imaging: Embedding issues

    International Nuclear Information System (INIS)

    Aurino, M; Tuerer, I; Martinez, A; Gensbittel, A; Degardin, A F; Kreisler, A J

    2010-01-01

    High-T c hot-electron bolometers (HEB) are an interesting alternative to other superconducting heterodyne mixers in the terahertz frequency range because of low-cost cooling investment, ultra-wide instantaneous bandwidth and low intrinsic noise level, even at 80 K. A technological process to fabricate stacked yttrium-based (YBCO) / praseodymium-based (PBCO) ultra-thin films (in the 15 to 40 nm thickness range) etched to form 0.5 μm x 0.5 μm constrictions, elaborated on (100) MgO substrates, has been previously described. Ageing effects were also considered, with the consequence of increased electrical resistance, significant degradation of the regular THz response and no HEB mixing action. Electron and UV lithography steps are revisited here to realize HEB mixers based on nano-bridges covered by a log-periodic planar gold antenna, dedicated to the 1 to 7 THz range. Several measures have been attempted to reduce the conversion losses, mainly by considering the embedding issues related to the YBCO nano-bridge impedance matching to the antenna and the design of optimized intermediate frequency circuitry. Antenna simulations were performed and validated through experiments on scaled models at GHz frequencies. Electromagnetic coupling to the incoming radiation was also studied, including crosstalk between neighbour antennas forming a linear imaging array.

  20. Outcomes of patients presenting to a dedicated rapid access lung cancer clinic.

    LENUS (Irish Health Repository)

    Dunican, E

    2012-02-01

    We examined the outcomes of the first 500 patients referred to a dedicated Rapid Access Lung Cancer Clinic. A total of 206 patients (41.2%) were diagnosed with a thoracic malignancy; 179 had primary lung cancer and 27 had secondary or other thoracic cancers. Pulmonary nodules requiring ongoing surveillance were found in a further 79 patients (15.8%). Of those patients found to have primary lung cancer, 24 (13.4%) had Small Cell and 145 (81%) had Non Small Cell Lung Cancer. In patients with Non small cell tumours, 26 (21.1%) were stage 1, 14 (11.4%) stage II, 37 (30.1%) stage III and 46 (37.4%) stage IV at diagnosis. For the 129 patients (72%) in whom the thoracic MDT recommended active treatment, primary therapy was surgical resection in 44 (24.6%), combined chemoradiation in 31 patients (17.3%), chemotherapy alone in 39 (21.8%) and radiation in 15 (8.4%).

  1. A dedicated intravenous cannula for postoperative use effect on incidence and severity of phlebitis.

    LENUS (Irish Health Repository)

    Panadero, A

    2012-02-03

    A prospective, randomised, controlled clinical study was performed to compare the incidence and severity of postoperative peripheral venous thrombophlebitis associated with a single intravenous cannula used for both intra-operative and postoperative purposes, and two cannulae, one used intra-operatively and the other postoperatively. Sixty American Society of Anaesthesiologists (ASA) physical status I or II patients aged 18-65 years undergoing elective surgery were studied. The technique of cannula insertion was standardised. After surgery, the cannulation sites were examined daily by a blinded investigator for the presence and severity of thrombophlebitis using the Baxter Scale. The two groups were similar in terms of age, gender, weight, type and duration of surgical procedures, and drugs and fluids administered both intra-operatively and postoperatively. The proportion of patients that developed phlebitis was significantly less in the two cannulae group (26.1%) than in the single cannula group (63.3%) (p < 0.0001). The severity of phlebitis was greater in the single cannula group than in the two cannulae group. These results indicate that the use of a dedicated cannula for postoperative use decreases the incidence and severity of postoperative, peripheral, cannula-related phlebitis.

  2. Dedicated brain PET system of PET/MR for brain research

    International Nuclear Information System (INIS)

    Cheng, Li; Liu, Yaqiang; Ma, Tianyu; Wang, Shi; Wei, Qingyang; Xu, Tianpeng

    2015-01-01

    This work is to replace PET ring in human brain PET/MR system with a dedicated wearable PET insert, aimed at improving both patient feasibility and system performance for brain imaging. The designed PET/MR system includes two parts: the inside parts, including a radio frequency (RF) coil and PET ring, are mounted on patient’s head, and the outside part, a MR imager, is dependent of patient. The RF coil is the innermost layer, surrounded by an outer PET-ring layer. They are supported by a MRcompatible structure. And both RF coil and PET detectors are placed inside a standard clinical 3-T MR imager. From the design of the system we can infer that some advantages can be achieved. First, high sensitivity will be achieved with the same amount crystals as the PET ring is more close to region-of-interest area, at a reduced cost. Second, by using a 2-layer depth of interaction (DOI) detector, the parallax effect can be minimized. The resolution will benefit from short positron range caused by magnetic field and smaller ring diameter will also reduce the effect of non-collinearity. Thirdly, as the PET ring is mounted on head, impact of patient motion will be reduced.

  3. Performance evaluation of a 'dual-side read' dedicated mammography computed radiography system

    International Nuclear Information System (INIS)

    Fetterly, Kenneth A.; Schueler, Beth A.

    2003-01-01

    The image quality of a dedicated mammography computed radiography (CR) system was characterized. A unique feature of this system is that it collects image signals from both sides of the storage phosphor. Measurements of the modulation transfer function (MTF), noise power spectrum (NPS), and detective quantum efficiency (DQE) were made. This work included improvements in our measurement methods to specifically account for the detrimental effects of system glare on the MTF and to accurately characterize the low-frequency NPS components. Image quality measurements were performed using a 25 kVp beam filtered with 2 mm Al and an exposure range of 1 to 100 mR (87 to 870 μGy). The DQE was found to decrease with increasing exposure due to an increased contribution of storage phosphor structure noise. The DQE of this system was compared to similar measurements made using a standard CR system. The dual-side read system demonstrated superior DQE compared to the standard system. The decrease in DQE with increasing exposure was more severe for the standard system than the dual-side read system. This finding suggests that the CR system noise was reduced for the dual-side read system compared to the standard system

  4. Design of the dipole and quadrupole magnets of the dedicated proton synchrotron for hadron therapy

    International Nuclear Information System (INIS)

    Kukarnikov, S.I.; Makoveev, V.K.; Minashkin, V.F.; Molodozhentsev, A.Yu.; Shevtsov, V.F.; Sidorov, G.I.

    1998-01-01

    The 2D-calculation results of magnetic elements of the PRAMES (Prague Medical Synchrotron) are presented. This machine is a dedicated accelerator for cancer therapy. The output energy of the beam should be variable in the range 60-220 MeV. The maximum magnetic field of the dipole magnet should be 1.2 T, the maximum magnetic field ramp - less than 8 T/s. The focusing structure of the proton synchrotron consists of 8 dipole and 18 quadrupole magnets. All magnets are laminated to minimize leakage currents. The dipoles are parallel-edge, H-type magnets. The field uniformity should be of the order of ± 1 x 10 -4 in the working area (± 63 mm and ± 27 mm in the horizontal and vertical planes, respectively). The maximum magnetic field on the pole of the quadrupole lenses should be less than 1 T. The gradient uniformity of quadrupole magnets in the working region should be less than ± 3.5 x 10 -4

  5. Experimental Analysis of File Transfer Rates over Wide-Area Dedicated Connections

    Energy Technology Data Exchange (ETDEWEB)

    Rao, Nageswara S. [ORNL; Liu, Qiang [ORNL; Sen, Satyabrata [ORNL; Hinkel, Gregory Carl [ORNL; Imam, Neena [ORNL; Foster, Ian [University of Chicago; Kettimuthu, R. [Argonne National Laboratory (ANL); Settlemyer, Bradley [Los Alamos National Laboratory (LANL); Wu, Qishi [University of Memphis; Yun, Daqing [Harrisburg University

    2016-12-01

    File transfers over dedicated connections, supported by large parallel file systems, have become increasingly important in high-performance computing and big data workflows. It remains a challenge to achieve peak rates for such transfers due to the complexities of file I/O, host, and network transport subsystems, and equally importantly, their interactions. We present extensive measurements of disk-to-disk file transfers using Lustre and XFS file systems mounted on multi-core servers over a suite of 10 Gbps emulated connections with 0-366 ms round trip times. Our results indicate that large buffer sizes and many parallel flows do not always guarantee high transfer rates. Furthermore, large variations in the measured rates necessitate repeated measurements to ensure confidence in inferences based on them. We propose a new method to efficiently identify the optimal joint file I/O and network transport parameters using a small number of measurements. We show that for XFS and Lustre with direct I/O, this method identifies configurations achieving 97% of the peak transfer rate while probing only 12% of the parameter space.

  6. Lost to follow-up for appointments in a dedicated dry eye clinic

    Science.gov (United States)

    Poon, Kip Hoe; Yeo, Sharon; Tong, Louis

    2014-01-01

    Objective Dry eye is a prevalent condition with significant socioeconomic burden. This study evaluates the extent and reasons for loss to follow-up (LTF) in a dedicated dry eye clinic. LTF refers to patient who discontinued visits for >2 years. Method The proportion of patients LTF and the demographics in a cohort of dry eye patients (2006 to 2010) were determined. A telephone survey was prospectively conducted for patients who were LTF. Results Of 505 patients, 240 (47.5%) were LTF. Associated demographic factors for LTF were male sex, non-Chinese ethnicity, and age group dry eye condition (47%), personal/social factors (25%) and perceived insufficiency of healthcare delivery (28%). Only two (1.1%) were considered as management failures. The younger patients (age dry eye disease, compared to older patients who were more likely to be LTF due to personal/social reasons (P=0.02). Poor communication and service factors under healthcare delivery were found to be higher (P=0.002) in those who visited once before they were LTF (8.5%) compared to those who visited multiple times before they were LTF (0.1%). Conclusion LTF was relatively common in hospital-based dry eye management. Female and older patients were less likely to stop consultation. Stabilized dry eye condition, common in younger patients, was the most common reason for LTF. Elderly patients have difficulty attending clinics due to nonmedical problems, which may require a more holistic approach. PMID:25336929

  7. Thermoset polymers chemo-rheology dedicated to reactive rotational moulding (RRM) understanding and control

    International Nuclear Information System (INIS)

    Viale, J.

    2009-12-01

    This study comes within the scope of New Technology for Energy, particularly for high pressure hydrogen storage. Reactive Rotational Moulding has been identified as an adapted process for hydrogen-tight liners manufacturing. Thus the Reactive Rotational Moulding process has been studied in order to find theoretical tools dedicated to the understanding of such a reactive forming process. Chemical kinetics of four polyurethanes and poly-epoxides reactive systems have been determined on classical isothermal conditions and original aniso-thermal conditions i.e. on temperature ramps. Aniso-thermal conditions have been selected because they corresponds better to real process conditions. Rheological behaviour have also been characterized on two different approaches, an isothermal one and on temperature ramps. In particular, viscosity have been described as a function of heating rate. These physical and chemical results have been compiled in an original state diagram in order to show material properties evolution in a time-temperature space. The whole ex situ characterizations are then managed to described the behavior of the different formulations during the rotational moulding. Moreover they allow to form specific materials and so to widen the range of material to thermoset polymers. Finally, in order to correlate theoretical deduction to real reactive systems evolution, the elaboration of innovating monitoring tool based on ultrasonic analysis has been studied. To begin, polymerization monitoring criteria have been identified and then specific techniques have been set to monitor these criteria in real forming process. (author)

  8. A dedicated database system for handling multi-level data in systems biology.

    Science.gov (United States)

    Pornputtapong, Natapol; Wanichthanarak, Kwanjeera; Nilsson, Avlant; Nookaew, Intawat; Nielsen, Jens

    2014-01-01

    Advances in high-throughput technologies have enabled extensive generation of multi-level omics data. These data are crucial for systems biology research, though they are complex, heterogeneous, highly dynamic, incomplete and distributed among public databases. This leads to difficulties in data accessibility and often results in errors when data are merged and integrated from varied resources. Therefore, integration and management of systems biological data remain very challenging. To overcome this, we designed and developed a dedicated database system that can serve and solve the vital issues in data management and hereby facilitate data integration, modeling and analysis in systems biology within a sole database. In addition, a yeast data repository was implemented as an integrated database environment which is operated by the database system. Two applications were implemented to demonstrate extensibility and utilization of the system. Both illustrate how the user can access the database via the web query function and implemented scripts. These scripts are specific for two sample cases: 1) Detecting the pheromone pathway in protein interaction networks; and 2) Finding metabolic reactions regulated by Snf1 kinase. In this study we present the design of database system which offers an extensible environment to efficiently capture the majority of biological entities and relations encountered in systems biology. Critical functions and control processes were designed and implemented to ensure consistent, efficient, secure and reliable transactions. The two sample cases on the yeast integrated data clearly demonstrate the value of a sole database environment for systems biology research.

  9. A readout circuit dedicated for the detection of chemiluminescence using a silicon photomultiplier

    Science.gov (United States)

    Baszczyk, M.; Dorosz, P.; Mik, L.; Kucewicz, W.; Reczynski, W.; Sapor, M.

    2018-05-01

    A readout circuit dedicated for the detection of the chemiluminescence phenomenon using a silicon photomultiplier (SiPM) is presented. During chemiluminescence, light is generated as a result of chemical reaction. Chemiluminescence is used in many applications within medicine, chemistry, biology and biotechnology, and is one of the most important sensing techniques in biomedical science and clinical medicine. The front-end electronics consist of a preamplifier and a fast shaper—this produces pulses, the peaking time which is 3.6 ns for a single photon and the FWHM is 3.8 ns. The system has been optimised to measure chemiluminescence—it is sensitive at the level of single photons, it generates a low number of overlapping pulses and is accurate. Two methods of signal detection are analysed and compared: the counting of events and amplitude detection. The relationship between the chemiluminescence light intensity and the concentration of the chemical compound (luminol) is linear in the range of the tested concentrations and has strong linearity parameters and low prediction intervals.

  10. The new dedicated PIXE set-up at the National Environmental Research Institute, Denmark

    International Nuclear Information System (INIS)

    Kemp, Ka ring re; Waahlin, Peter

    1999-01-01

    The Niels Bohr Institute in Copenhagen was in the beginning of the 70'es one of the early places for PIXE. Contributions were made to the theoretical interpretation of the PIXE spectra as well as the practical application. The home-made 4 MV van de Graaff accelerator at the Niels Bohr Institute was an excellent tool for PIXE. The accelerator, which was used for many years, has now found its place on a museum after more than 40 years of active service. A dedicated PIXE set-up has now been established at the National Environmental Research Institute using a new 1.7 MV Tandem Pelletron (5SDH) from NEC. The main application is elemental analysis of outdoor aerosols. The main work is unsophisticated macro analyses, which do not push the equipment to its limits. This enables automated analysis of about 10,000 samples per year using very limited manpower resources. The research focuses on the contribution from various source types to the atmosphere over Europe, the North Atlantic and Greenland. Source compositions and their temporal variations are studied

  11. M-l Swaco opens industry's only dedicated CRI training centre

    Energy Technology Data Exchange (ETDEWEB)

    Robertson, John; Wilkinson, Tony; Minton, Reg

    2005-07-01

    Recognising the growing attraction of cuttings re-injection (CRI) as a viable drilling waste management option in the North Sea and other zero discharge environments, M-I Swaco has officially unveiled the industry's only dedicated CRI training center in Aberdeen. Located in Aliens Industrial Estate, the all-inclusive facility includes two training rooms, two project specific CRI training simulators, one CRI full-scale slurrification system, one Cleancut cuttings collection and transport system, a vacuum cuttings collection system and a 518 Centrifuge. The center, which can accommodate up to 12 students at one time, is fully equipped to deliver both theoretical and practical hands-on training in all aspects of the CRI process. Training at the center is competency-based and follows ISO 9001 and ISO 10015 requirements. The training centre is a natural extension of the newly established M-I Swaco CRI Assurance Program, or CAP the core of which is a geomechanics team organised to provide integrated CRI services that include engineering, monitoring and assurance capabilities for operators worldwide.

  12. The Dedication to Heracles Rheginus from Castellace of Oppido Mamertina: an Ephebic Inscription?

    Directory of Open Access Journals (Sweden)

    Valentina Consoli

    2013-07-01

    Full Text Available A wide literary tradition narrated by D.S., 4.22.5, tied to musical legends concerning the cicadas on the Alex river, refers to the passage of Heracles across the boundary territory between Rhegion and Locri. The careful reading of the texts, however, induces us to set the known episode about Heracles, disturbed by cicadas while resting, on the northern boundary between the two chorai along the Tyrrhenian side, within the area marked by a strong conflict between the two rival apoikiai. The bronze leaf with the inscription to Heracles Rheginus just comes from this border area of Rhegion chora, inside the district of Metauros river, signed by both indigenous settlements and Locresian claims. The inscription should not be taken as a certain clue for the existence of a sanctuary of the hero, but can represent a clear sign of his strong presence as a cultic reference for the Rheginian scattered through the colonial eschatia. Both analyzing the inscription historical-cultural context of provenance and considering the liminal worshiping places of the heros-theos, linked to the youth rites of passage, we could explain the rise of the dedication referring to the activity of the ephebes garrisoning the colonial chora.

  13. Dedicated search for the time evolution of an electron neutrino beam at the Brookhaven AGS

    International Nuclear Information System (INIS)

    Bionta, R.; LoSecco, J.; Ong, R.; Stone, J.; Sulak, L.; Watts, R.; Cortez, B.; Foster, G.W.

    1981-01-01

    An experiment dedicated to the study of the time evolution of a neutrino beam enriched with ν/sub e/'s is suggested as feasible. It appears that the highest fluxes can be achieved with current beam lines at the Brookhaven AGS or the CERN PS. A configuration optimized for good sensitivity to neutrino eigenmass differences from 1 eV to 20 eV and mixing (Pontecorvo) angles down to 15 0 (comparable to the Cabibbo angle) is considered. The ν/sub e/ beam is formed using K/sub e3/ 0 decays. A simultaneously produced ν/sub μ/ beam from K/sub μ3/ 0 decay serves as the normalizer. Pion generated ν/sub μ/'s are suppressed to limit background. A massive detector is employed to obtain sufficient statistical power. It consists of a series of seven water Cerenkov modules (each with 180T fiducial mass), judiciously spaced along the ν line to provide flight paths from 40 m to 1000 m. The detector elements duplicate a recently developed technology that is eminently suited to this investigation. Simulation and reconstruction of neutrino events in a detector similar to the one suggested show sufficient resolution in angle, energy, position and event timing relative to the beam

  14. Identification of organic components and commercial grade dedication using Fourier Transform near infrared spectroscopy

    International Nuclear Information System (INIS)

    Azizian, H.

    2000-01-01

    The over all quality assurance programs for the design, fabrication, and construction of nuclear power plants, both in Canada and USA have long been established. A need for an acceptance process to allow the use of commercial grade items to be utilized in safety related applications has been recognized. A guideline in the EPRI NP-5652 report and in the Appendix D of the CAN3-N286.2-86 standard is outlined for testing of commercial grade components. A new nondestructive and cost effective NIR identification technology is now available to meet the above requirements. The Fourier Transform near infrared spectroscopy (FT-NIR), in the past, has shown to have the capabilities to identify cable insulation non-destructively and in-situ. This paper presents data to show the diversity of the NIR technology in the identification of three different non-metallic materials (wire insulation, 0-rings, and greases, all part of the operation of the safety related equipment) for the purposes of quality assurance, quality control, and the commercial grade dedication of components. The enhanced quality control and quality assurance will result in significant savings not only in testing but also in the continuous and reliable operations of power plants. (author)

  15. A Novel Vaping Machine Dedicated to Fully Controlling the Generation of E-Cigarette Emissions

    Directory of Open Access Journals (Sweden)

    Sébastien Soulet

    2017-10-01

    Full Text Available The accurate study of aerosol composition and nicotine release by electronic cigarettes is a major issue. In order to fully and correctly characterize aerosol, emission generation has to be completely mastered. This study describes an original vaping machine named Universal System for Analysis of Vaping (U-SAV, dedicated to vaping product study, enabling the control and real-time monitoring of applied flow rate and power. Repeatability and stability of the machine are demonstrated on flow rate, power regulation and e-liquid consumption. The emission protocol used to characterize the vaping machine is based on the AFNOR-XP-D90-300-3 standard (15 W power, 1 Ω atomizer resistance, 100 puffs collected per session, 1.1 L/min airflow rate. Each of the parameters has been verified with two standardized liquids by studying mass variations, power regulation and flow rate stability. U-SAV presents the required and necessary stability for the full control of emission generation. The U-SAV is recognised by the French association for standardization (AFNOR, European Committee for Standardization (CEN and International Standards Organisation (ISO as a vaping machine. It can be used to highlight the influence of the e-liquid composition, user behaviour and nature of the device, on the e-liquid consumption and aerosol composition.

  16. Dedicator of cytokinesis 8 mutation related combined immune deficiency: A single centre experience from India

    Directory of Open Access Journals (Sweden)

    Dhwanee Thakkar

    2017-10-01

    Full Text Available The Dedicator of cytokinesis 8 (DOCK8 related combined immune deficiency is a recently discovered entity which differs from the classic STAT3 associated autosomal dominant hyper-IgE syndrome with respect to the genetic origin and the clinical manifestations. It is characterised by increased risk of autoimmunity, malignancy and neurological complications in addition to increased risk of recurrent cutaneous, sinopulmonary and gastrointestinal infections. We report a series 11 children from three families suffering from DOCK8 related combined immunodeficiency. Out of 11 children only 5 were alive at diagnosis and rest 6 were siblings who had died of similar complaints. Among the 5 children only one underwent allogeneic haploidentical stem cell transplant (SCT from his mother but died before engraftment due to infection. Other 4 are alive without SCT but have multiple co-morbidities. A constellation of cutaneous lesions, recurrent sinopulmonary & gastro intestinal infections and allergic manifestations in a child who may have a similar family history should arouse a suspicion of combined immunodeficiency associated with DOCK8 mutation. Early diagnosis in such children can expedite the appropriate management with SCT. Keywords: Combined immunodeficiency, DOCK8, Children

  17. Experiments and Analyses of Data Transfers Over Wide-Area Dedicated Connections

    Energy Technology Data Exchange (ETDEWEB)

    Rao, Nageswara S. [ORNL; Liu, Qiang [ORNL; Sen, Satyabrata [ORNL; Hanley, Jesse A. [ORNL; Foster, Ian [University of Chicago; Kettimuthu, R. [Argonne National Laboratory (ANL); Wu, Qishi [University of Memphis; Yun, Daqing [Harrisburg University; Towsley, Don [University of Massachusetts, Amherst; Vardoyan, Gayane [University of Massachusetts, Amherst

    2017-08-01

    Dedicated wide-area network connections are increasingly employed in high-performance computing and big data scenarios. One might expect the performance and dynamics of data transfers over such connections to be easy to analyze due to the lack of competing traffic. However, non-linear transport dynamics and end-system complexities (e.g., multi-core hosts and distributed filesystems) can in fact make analysis surprisingly challenging. We present extensive measurements of memory-to-memory and disk-to-disk file transfers over 10 Gbps physical and emulated connections with 0–366 ms round trip times (RTTs). For memory-to-memory transfers, profiles of both TCP and UDT throughput as a function of RTT show concave and convex regions; large buffer sizes and more parallel flows lead to wider concave regions, which are highly desirable. TCP and UDT both also display complex throughput dynamics, as indicated by their Poincare maps and Lyapunov exponents. For disk-to-disk transfers, we determine that high throughput can be achieved via a combination of parallel I/O threads, parallel network threads, and direct I/O mode. Our measurements also show that Lustre filesystems can be mounted over long-haul connections using LNet routers, although challenges remain in jointly optimizing file I/O and transport method parameters to achieve peak throughput.

  18. Challenges for embedded electronics in systems used in future facilities dedicated to international physics programs

    Energy Technology Data Exchange (ETDEWEB)

    Flament, O.; Bazzoli, S.; Girard, S.; Raimbourg, J.; Sauvestre, J. E. [CEA, DIF, F-91297 Arpajon (France); Baggio, J. [CEA, CESTA, F33830, Le Barp (France); Leray, J. L. [CEA, F-91191 Gif-sur-Yvette (France)

    2009-07-01

    The implementation of equipment with embedded electronic to monitor, control, measure and operate future large facilities dedicated to high energy physics or nuclear fusion are necessary. Reliable operation of these equipment will be achieved through availability and reliability analysis. In several cases, the equipment selection or development approach has to be done by considering a harsh environment in terms of radiations. In order to implement these systems in such environments shielding, location and distance from the source must be considered to reduce, to protect and to avoid radiation effects. People in charge of the choice of the equipment have to take into account and mitigate radiation effects from subsystem to system level. It is beyond the scope of this paper to address all the radiation effects: the electromagnetic effects are not dealt with. This paper is organised as follows: we describe the electronics and semiconductor trends in today applications, then we present the radiation effects and their impact on the device response and eventually we review different ways to mitigate these impacts

  19. Operational performance of a congested corridor with lanes dedicated to autonomous vehicle traffic

    Directory of Open Access Journals (Sweden)

    Zachary Vander Laan

    2017-06-01

    Full Text Available This paper considers the operational performance impact of autonomous vehicles (AV on a multi-lane freeway corridor with separate lanes dedicated to AV and non-AV traffic. Autonomous vehicle behavior is modeled at the macroscopic level by modifying the fundamental diagram relating hourly traffic flow and vehicle density, a step that is justified by adjusting a parameter from Newell’s car-following model at the microscopic level and transforming back to a macroscopic representation. The model is applied to the I-95 corridor between Washington, DC and Baltimore, MD during the PM peak period, where the impact of introducing a managed AV-only lane is assessed at varying penetration rates of autonomous vehicles. The results show that the overall corridor performance metrics improve with increasing penetration rates up to 30%, 40% or 50% (depending on the underlying assumptions that govern AV behavior, after which the performance deteriorates drastically. Implications of the results are discussed in light of the per-lane and aggregated metrics, and future directions for research are proposed.

  20. Evaluation of a video-based head motion tracking system for dedicated brain PET

    Science.gov (United States)

    Anishchenko, S.; Beylin, D.; Stepanov, P.; Stepanov, A.; Weinberg, I. N.; Schaeffer, S.; Zavarzin, V.; Shaposhnikov, D.; Smith, M. F.

    2015-03-01

    Unintentional head motion during Positron Emission Tomography (PET) data acquisition can degrade PET image quality and lead to artifacts. Poor patient compliance, head tremor, and coughing are examples of movement sources. Head motion due to patient non-compliance can be an issue with the rise of amyloid brain PET in dementia patients. To preserve PET image resolution and quantitative accuracy, head motion can be tracked and corrected in the image reconstruction algorithm. While fiducial markers can be used, a contactless approach is preferable. A video-based head motion tracking system for a dedicated portable brain PET scanner was developed. Four wide-angle cameras organized in two stereo pairs are used for capturing video of the patient's head during the PET data acquisition. Facial points are automatically tracked and used to determine the six degree of freedom head pose as a function of time. The presented work evaluated the newly designed tracking system using a head phantom and a moving American College of Radiology (ACR) phantom. The mean video-tracking error was 0.99±0.90 mm relative to the magnetic tracking device used as ground truth. Qualitative evaluation with the ACR phantom shows the advantage of the motion tracking application. The developed system is able to perform tracking with accuracy close to millimeter and can help to preserve resolution of brain PET images in presence of movements.

  1. A Novel Vaping Machine Dedicated to Fully Controlling the Generation of E-Cigarette Emissions.

    Science.gov (United States)

    Soulet, Sébastien; Pairaud, Charly; Lalo, Hélène

    2017-10-14

    The accurate study of aerosol composition and nicotine release by electronic cigarettes is a major issue. In order to fully and correctly characterize aerosol, emission generation has to be completely mastered. This study describes an original vaping machine named Universal System for Analysis of Vaping (U-SAV), dedicated to vaping product study, enabling the control and real-time monitoring of applied flow rate and power. Repeatability and stability of the machine are demonstrated on flow rate, power regulation and e-liquid consumption. The emission protocol used to characterize the vaping machine is based on the AFNOR-XP-D90-300-3 standard (15 W power, 1 Ω atomizer resistance, 100 puffs collected per session, 1.1 L/min airflow rate). Each of the parameters has been verified with two standardized liquids by studying mass variations, power regulation and flow rate stability. U-SAV presents the required and necessary stability for the full control of emission generation. The U-SAV is recognised by the French association for standardization (AFNOR), European Committee for Standardization (CEN) and International Standards Organisation (ISO) as a vaping machine. It can be used to highlight the influence of the e-liquid composition, user behaviour and nature of the device, on the e-liquid consumption and aerosol composition.

  2. Conception and test of Echoes, a spectro-imager dedicated to the seismology of Jupiter

    Science.gov (United States)

    Soulat, L.; Schmider, F.-X.; Robbe-Dubois, S.; Appourchaux, T.; Gaulme, P.; Bresson, Y.; Gay, J.; Daban, J.-B.; Gouvret, C.

    2017-11-01

    Echoes is a project of a spaceborne Doppler Spectro-Imager (DSI) which has been proposed as payload to the JUICE mission project selected in the Cosmic Vision program of the European Space Agency (ESA). It is a Fourier transform spectrometer which measures phase shifts in the interference patterns induced by Doppler shifts of spectral lines reflected at the surface of the planet. Dedicated to the seismology of Jupiter, the instrument is designed to analyze the periodic movements induced by internal acoustic modes of the planet. It will allow the knowledge of the internal structure of Jupiter, in particular of the central region, which is essential for the comprehension of the scenario of the giant planets' formation. The optical design is based on a modified Mach-Zehnder interferometer operating in the visible domain and takes carefully into account the sensitivity of the optical path difference to the temperature. The instrument produces simultaneously four images in quadrature which allows the measurement of the phase without being contaminated by the continuum component of the incident light. We expect a noise level less than 1 cm2s-2µHz-1 in the frequency range [0.5 -10] mHz. In this paper, we present the prototype implemented at the Observatoire de la Côte d'Azur (OCA) in collaboration with Institut d'Astrophysique Spatiale (IAS) to study the real performances in laboratory and to demonstrate the capability to reach the required Technology Readiness Level 5.

  3. A dedicated AMS setup for 53Mn/60Fe at the Cologne FN tandem accelerator

    Science.gov (United States)

    Schiffer, M.; Dewald, A.; Feuerstein, C.; Altenkirch, R.; Stolz, A.; Heinze, S.

    2015-10-01

    Following demands for AMS measurements of medium mass isotopes, especially for 53Mn and 60Fe, we started to build a dedicated AMS setup at the Cologne FN tandem accelerator. This accelerator with a maximum terminal voltage of 10 MV can be reliably operated at a terminal voltage of 9.5 MV which corresponds to energies of 93-102 MeV for 60Fe or 53Mn beams using the 9+ or 10+ charge state. These charge states can be obtained by foil stripping with efficiencies of 30% and 20%, respectively. Energies around 100 MeV are sufficient to effectively suppress the stable isobars 60Ni and 53Cr by (dE/dx) techniques using combinations of energy degrader foils and dispersive elements like electrostatic analyzers and time of flight (TOF) systems as well as (dE/dx)E ion detectors. In this contribution we report on the actual status of the AMS setup and discuss details and expected features.

  4. Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification

    Science.gov (United States)

    Tessarz, Peter; Santos-Rosa, Helena; Robson, Sam C.; Sylvestersen, Kathrine B.; Nelson, Christopher J.; Nielsen, Michael L.; Kouzarides, Tony

    2014-01-01

    Nucleosomes are decorated with numerous post-translational modifications capable of influencing many DNA processes. Here we describe a new class of histone modification, methylation of glutamine, occurring on yeast histone H2A at position 105 (Q105) and human H2A at Q104. We identify Nop1 as the methyltransferase in yeast and demonstrate that fibrillarin is the orthologue enzyme in human cells. Glutamine methylation of H2A is restricted to the nucleolus. Global analysis in yeast, using an H2AQ105me-specific antibody, shows that this modification is exclusively enriched over the 35S ribosomal DNA transcriptional unit. We show that the Q105 residue is part of the binding site for the histone chaperone FACT (facilitator of chromatin transcription) complex. Methylation of Q105 or its substitution to alanine disrupts binding to FACT in vitro. A yeast strain mutated at Q105 shows reduced histone incorporation and increased transcription at the ribosomal DNA locus. These features are phenocopied by mutations in FACT complex components. Together these data identify glutamine methylation of H2A as the first histone epigenetic mark dedicated to a specific RNA polymerase and define its function as a regulator of FACT interaction with nucleosomes.

  5. Challenges for embedded electronics in systems used in future facilities dedicated to international physics programs

    International Nuclear Information System (INIS)

    Flament, O.; Bazzoli, S.; Girard, S.; Raimbourg, J.; Sauvestre, J. E.; Baggio, J.; Leray, J. L.

    2009-01-01

    The implementation of equipment with embedded electronic to monitor, control, measure and operate future large facilities dedicated to high energy physics or nuclear fusion are necessary. Reliable operation of these equipment will be achieved through availability and reliability analysis. In several cases, the equipment selection or development approach has to be done by considering a harsh environment in terms of radiations. In order to implement these systems in such environments shielding, location and distance from the source must be considered to reduce, to protect and to avoid radiation effects. People in charge of the choice of the equipment have to take into account and mitigate radiation effects from subsystem to system level. It is beyond the scope of this paper to address all the radiation effects: the electromagnetic effects are not dealt with. This paper is organised as follows: we describe the electronics and semiconductor trends in today applications, then we present the radiation effects and their impact on the device response and eventually we review different ways to mitigate these impacts

  6. A Novel Dedicated Route Protection Scheme for Survivability of Link Failure in Elastic Optical Networks

    Directory of Open Access Journals (Sweden)

    Sridhar Iyer

    2017-11-01

    Full Text Available The spectrally efficient transportation of the high bit rate(s data is achievable by the Elastic optical networks (EONs. However, in the EONs, owing to the failure occurrence even in an individual simple element, different service(s maybe interrupted. Hence, it is imperative that the schemes for survivability be developed so that the issues due to the possible failure(s can be overcome. In the current work, in view of survivability of the link failure(s in the EONs, we propose the Spectrum Continuity and Contiguity Established DRP (SCC-E-DRP algorithm which is a novel dedicated route protection (DRP scheme that attempts to avoid the problem of trap topology during its exploration for a pair of link disjoint path. Further, to evaluate the link disjoint paths, we resort to the use of the SCC Established Shortest Route (SCC-E-SR algorithm which is a modified Dijkstra’s algorithm based scheme that selects the path(s pair(s based on the end-toend SCC. We conduct extensive simulations considering realistic network topologies, and compare the performance of the SCCE-DRP scheme with the existing techniques. The obtained results show that, compared to the existing schemes, the SCC-E-DRP scheme achieves better results in terms of blocking probability.

  7. CALIFA, a Dedicated Calorimeter for the R{sup 3}B/FAIR

    Energy Technology Data Exchange (ETDEWEB)

    Cortina-Gil, D., E-mail: d.cortina@usc.es [Universidad de Santiago de Compostela, E-15782 Santiago de Compostela (Spain); Alvarez-Pol, H. [Universidad de Santiago de Compostela, E-15782 Santiago de Compostela (Spain); Aumann, T. [Technische Universität Darmstadt, D-64289 Darmstadt (Germany); Helmholtzzentrum für Schwerionenforschung, D-64291 Darmstadt (Germany); Avdeichikov, V. [University of Lund, SE 221 00 Lund (Sweden); Bendel, M. [Technische Universität München, D-85748 Garching (Germany); Benlliure, J. [Universidad de Santiago de Compostela, E-15782 Santiago de Compostela (Spain); Bertini, D. [Helmholtzzentrum für Schwerionenforschung, D-64291 Darmstadt (Germany); Bezbakh, A. [Joint Institute for Nuclear Research, RU-141980 Dubna (Russian Federation); Bloch, T. [Technische Universität Darmstadt, D-64289 Darmstadt (Germany); Böhmer, M. [Technische Universität München, D-85748 Garching (Germany); Borge, M.J.G.; Briz, J.A. [Instituto Estructura de la Materia, CSIC, E-28006 Madrid (Spain); Cabanelas, P. [Universidad de Santiago de Compostela, E-15782 Santiago de Compostela (Spain); Casarejos, E. [Universidad de Vigo, E-36310 Vigo (Spain); Carmona Gallardo, M. [Instituto Estructura de la Materia, CSIC, E-28006 Madrid (Spain); Cederkäll, J. [University of Lund, SE 221 00 Lund (Sweden); Chulkov, L. [Nuclear Reseach Center, Kurchatov Institute, RU-123182 Moscow (Russian Federation); Dierigl, M. [Technische Universität München, D-85748 Garching (Germany); Di Julio, D. [University of Lund, SE 221 00 Lund (Sweden); Durán, I. [Universidad de Santiago de Compostela, E-15782 Santiago de Compostela (Spain); and others

    2014-06-15

    The R{sup 3}B experiment (Reactions with Relativistic Radioactive Beams) at FAIR (Facility for Antiproton and Ion Research) is a versatile setup dedicated to the study of reactions induced by high-energy radioactive beams. It will provide kinematically complete measurements with high efficiency, acceptance and resolution, making possible a broad physics program with rare-isotopes. CALIFA (CALorimeter for In-Flight detection of gamma-rays and high energy charged pArticles), is a complex detector based on scintillation crystals, that will surround the target of the R{sup 3}B experiment. CALIFA will act as a total absorption gamma-calorimeter and spectrometer, as well as identifier of charged particles from target residues. This versatility is its most challenging requirement, demanding a huge dynamic range, to cover from low energy gamma-rays up to 300 MeV protons. This fact, along with the high-energy of the beams determine the conceptual design of the detector, presented in this paper, together with the technical solutions proposed for its construction.

  8. The Impact of a Dedicated Research Education Month for Anesthesiology Residents

    Directory of Open Access Journals (Sweden)

    Robert E. Freundlich

    2015-01-01

    Full Text Available An educational intervention was implemented at the University of Michigan starting in 2008, in which anesthesiology interns complete a dedicated month-long didactic rotation in evidence-based medicine (EBM and research methodology. We sought to assess its utility. Scores on a validated EBM test before and after the rotation were compared and assessed for significance of improvement. A survey was also given to gauge satisfaction with the quality of the rotation and self-reported improvement in understanding of EBM topics. Fourteen consecutive interns completed the research rotation during the study period. One hundred percent completed both the pre- and postrotation test. The mean pretest score was 7.78 ± 2.46 (median = 7.5, 0–15 scale, and interquartile range 7.0–10.0 and the mean posttest score was 10.00 ± 2.35 (median = 9.5, interquartile range 8.0–12.3, which represented a statistically significant increase (P=0.011, Wilcoxon signed-rank test. All fourteen of the residents “agreed” or “strongly agreed” that they would recommend the course to future interns and that the course increased their ability to critically review the literature. Our findings demonstrate that this can be an effective means of improving understanding of EBM topics and anesthesiology research.

  9. New beamline dedicated to solution scattering from biological macromolecules at the ESRF

    International Nuclear Information System (INIS)

    Pernot, P; Theveneau, P; Giraud, T; Fernandes, R Nogueira; Nurizzo, D; Spruce, D; Surr, J; McSweeney, S; Round, A; Felisaz, F; Foedinger, L; Gobbo, A; Huet, J; Villard, C; Cipriani, F

    2010-01-01

    The new bio-SAXS beamline (ID14-3 at the ESRF, Grenoble, France) is dedicated exclusively to small-angle scattering experiments of biological macromolecules in solution and has been in user operation since November 2008. Originally a protein crystallography beamline, ID14-3 was refurbished, still as a part of the ESRF Structural Biology group, with the main aim to provide a facility with 'quick and easy' access to satisfy rapidly growing demands from crystallographers, biochemists and structural biologists. The beamline allows manual and automatic sample loading/unloading, data collection, processing (conversion of a 2D image to a normalized 1D X-ray scattering profile) and analysis. The users obtain on-line standard data concerning the size (radius of gyration, maximum dimension and volume) and molecular weight of samples which allow on-the fly ab-inito shape reconstruction in order to provide feedback enabling the data collection strategies to be optimized. Automation of sample loading is incorporated on the beamline using a device constructed in collaboration between the EMBL (Grenoble and Hamburg outstations) and the ESRF. Semi/automated data analysis is implemented following the model of the SAXS facility at X33, EMBL Hamburg. This paper describes the bio-SAXS beamline and set-up characteristics together with the examples of user data obtained.

  10. Dedicated mobile volumetric cone-beam computed tomography for human brain imaging: A phantom study.

    Science.gov (United States)

    Ryu, Jong-Hyun; Kim, Tae-Hoon; Jeong, Chang-Won; Jun, Hong-Young; Heo, Dong-Woon; Lee, Jinseok; Kim, Kyong-Woo; Yoon, Kwon-Ha

    2015-01-01

    Mobile computed tomography (CT) with a cone-beam source is increasingly used in the clinical field. Mobile cone-beam CT (CBCT) has great merits; however, its clinical utility for brain imaging has been limited due to problems including scan time and image quality. The aim of this study was to develop a dedicated mobile volumetric CBCT for obtaining brain images, and to optimize the imaging protocol using a brain phantom. The mobile volumetric CBCT system was evaluated with regards to scan time and image quality, measured as signal-to-noise-ratio (SNR), contrast-to-noise-ratio (CNR), spatial resolution (10% MTF), and effective dose. Brain images were obtained using a CT phantom. The CT scan took 5.14 s at 360 projection views. SNR and CNR were 5.67 and 14.5 at 120 kV/10 mA. SNR and CNR values showed slight improvement as the x-ray voltage and current increased (p < 0.001). Effective dose and 10% MTF were 0.92 mSv and 360 μ m at 120 kV/10 mA. Various intracranial structures were clearly visible in the brain phantom images. Using this CBCT under optimal imaging acquisition conditions, it is possible to obtain human brain images with low radiation dose, reproducible image quality, and fast scan time.

  11. Development of a liquid xenon Compton telescope dedicated to functional medical imaging

    International Nuclear Information System (INIS)

    Grignon, C.

    2007-12-01

    Functional imaging is a technique used to locate in three dimensions the position of a radiotracer previously injected in a patient. The two main modalities used for a clinical application to detect tumors, the SPECT and the PET, use solid scintillators as a detection medium. The objective of this thesis was to investigate the possibility of using liquid xenon in order to benefit from the intrinsic properties of this medium in functional imaging. The feasibility study of such a device has been performed by taking into account the technical difficulties specific to the liquid xenon. First of all, simulations of a liquid xenon PET has been performed using Monte-Carlo methods. The results obtained with a large liquid xenon volume are promising : we can expect a reduction of the injected activity of radiotracer, an improvement of the spatial resolution of the image and a parallax free camera. The second part of the thesis was focused on the development of a new concept of medical imaging, the three gamma imaging, based on the use of a new emitter: the 44 scandium. Associated to a classical PET camera, the Compton telescope is used to infer the incoming direction of the third gamma ray by triangulation. Therefore, it is possible to reconstruct the position of each emitter in three dimensions. This work convinced the scientific community to support the construction and characterization of a liquid xenon Compton telescope. The first camera dedicated to small animal imaging should then be operational in 2009. (author)

  12. A dedicated on-line detecting system for auto air dryers

    Science.gov (United States)

    Shi, Chao-yu; Luo, Zai

    2013-10-01

    According to the correlative automobile industry standard and the requirements of manufacturer, this dedicated on-line detecting system is designed against the shortage of low degree automatic efficiency and detection precision of auto air dryer in the domestic. Fast automatic detection is achieved by combining the technology of computer control, mechatronics and pneumatics. This system can detect the speciality performance of pressure regulating valve and sealability of auto air dryer, in which online analytical processing of test data is available, at the same time, saving and inquiring data is achieved. Through some experimental analysis, it is indicated that efficient and accurate detection of the performance of auto air dryer is realized, and the test errors are less than 3%. Moreover, we carry out the type A evaluation of uncertainty in test data based on Bayesian theory, and the results show that the test uncertainties of all performance parameters are less than 0.5kPa, which can meet the requirements of operating industrial site absolutely.

  13. Dedicated brain PET system of PET/MR for brain research

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, Li; Liu, Yaqiang; Ma, Tianyu; Wang, Shi; Wei, Qingyang; Xu, Tianpeng [Institute of Medical Physics, Department of Engineering Physics, Tsinghua University, Beijing (China)

    2015-05-18

    This work is to replace PET ring in human brain PET/MR system with a dedicated wearable PET insert, aimed at improving both patient feasibility and system performance for brain imaging. The designed PET/MR system includes two parts: the inside parts, including a radio frequency (RF) coil and PET ring, are mounted on patient’s head, and the outside part, a MR imager, is dependent of patient. The RF coil is the innermost layer, surrounded by an outer PET-ring layer. They are supported by a MRcompatible structure. And both RF coil and PET detectors are placed inside a standard clinical 3-T MR imager. From the design of the system we can infer that some advantages can be achieved. First, high sensitivity will be achieved with the same amount crystals as the PET ring is more close to region-of-interest area, at a reduced cost. Second, by using a 2-layer depth of interaction (DOI) detector, the parallax effect can be minimized. The resolution will benefit from short positron range caused by magnetic field and smaller ring diameter will also reduce the effect of non-collinearity. Thirdly, as the PET ring is mounted on head, impact of patient motion will be reduced.

  14. Doses to nuclear technicians in a dedicated PET/CT centre utilising 18F fluorodeoxyglucose (FDG)

    International Nuclear Information System (INIS)

    Seierstad, T.; Stranden, E.; Bjering, K.; Evensen, M.; Holt, A.; Michalsen, H. M.; Wetteland, O.

    2007-01-01

    The first dedicated PET/CT centre in Norway was established at the Norwegian Radiumhospital in Oslo in 2005. Knowing that the introductions of PET-isotopes in nuclear medicine give increased occupational radiation dose to the technicians, a study was carried out in order to map the doses to staff members during different working operations and to see if any dose reducing measures were needed. The results of the study are in good agreement with other studies, and a technician dose of 20-25 nSv per injected MBq of 18 F seems to be representative for such centres. For an average injected activity of 350 MBq per patient, the dose limit is reached after handling around 3000 patients annually. For an annual number of less than 500 patients at the centre and rotation of the staff, an annual individual dose for the technicians would realistically be less than 2-3 mSv. Even a major increase in the number of patients will not result in individual doses near the ICRP dose limit. (authors)

  15. Dedicated Laboratory Setup for CO2 TEA Laser Propulsion Experiments at Rensselaer Polytechnic Institute

    International Nuclear Information System (INIS)

    Salvador, Israel I.; Kenoyer, David; Myrabo, Leik N.; Notaro, Samuel

    2010-01-01

    Laser propulsion research progress has traditionally been hindered by the scarcity of photon sources with desirable characteristics, as well as integrated specialized flow facilities in a dedicated laboratory environment. For TEA CO 2 lasers, the minimal requirements are time-average powers of >100 W), and pulse energies of >10 J pulses with short duration (e.g., 0.1 to 1 μs); furthermore, for the advanced pulsejet engines of interest here, the laser system must simulate pulse repetition frequencies of 1-10 kilohertz or more, at least for two (carefully sequenced) pulses. A well-equipped laser propulsion laboratory should have an arsenal of sensor and diagnostics tools (such as load cells, thrust stands, moment balances, pressure and heat transfer gages), Tesla-level electromagnet and permanent magnets, flow simulation facilities, and high-speed visualization systems, in addition to other related equipment, such as optics and gas supply systems. In this paper we introduce a cutting-edge Laser Propulsion Laboratory created at Rensselaer Polytechnic Institute, one of the very few in the world to be uniquely set up for beamed energy propulsion (BEP) experiments. The present BEP research program is described, along with the envisioned research strategy that will exploit current and expanded facilities in the near future.

  16. Providing nutritional support to patients with thoracic cancer: findings of a dedicated rehabilitation service.

    Science.gov (United States)

    Percival, Cheryl; Hussain, Asmah; Zadora-Chrzastowska, Sonja; White, Gillian; Maddocks, Matthew; Wilcock, Andrew

    2013-05-01

    National guidelines recommend screening patients with thoracic cancer to identify those requiring nutritional support. To help quantify this area of need, the associated workload and explore its impact, we report findings from a dedicated rehabilitation service. Patients were screened soon after diagnosis to determine the prevalence of malnutrition, and various aspects compared between malnourished and not malnourished groups. A nutritional care plan was instigated and all contacts recorded, together with follow-up body weight. Of 243 patients seen, 35% were malnourished which was associated with a palliative treatment intent (P group received oral nutritional supplements, but also experienced problems tolerating them. Over one month, neither the pattern nor magnitude of the change in weight differed between malnourished and not malnourished groups. Overall, weight was stable, increased or decreased in 52 (27%), 80 (42%) and 59 (31%) respectively, with no difference in overall survival (P = 0.16). Our data provides a pragmatic insight into the implications of following national guidance on nutritional screening and support in this patient group. Nutritional support failed to prevent weight loss in some patients, and did not appear to impact on survival; new assessments and treatments for cachexia are required. Copyright © 2013 Elsevier Ltd. All rights reserved.

  17. Time of flight measurements based on FPGA using a breast dedicated PET

    International Nuclear Information System (INIS)

    Aguilar, A; García-Olcina, R; Martos, J; Soret, J; Torres, J; Benlloch, J M; González, A J; Sánchez, F

    2014-01-01

    In this work the implementation of a Time-to-Digital Converter (TDC) using a Nutt delay line FPGA-based and applied on a Positron Emission Tomography (PET) device is going to be presented in order to check the system's suitability for Time of Flight (TOF) measurements. In recent years, FPGAs have shown great advantages for precise time measurements in PET. The architecture employed for these measurements is described in detail. The system developed was tested on a dedicated breast PET prototype, composed of LYSO crystals and Positive Sensitive Photomultipliers (PSPMTs). Two distinct experiments were carried out for this purpose. In the first test, system linearity was evaluated in order to calibrate the time measurements, providing a linearity error of less than 2% and an average time resolution of 1.4 ns FWHM. The second set of measurements tested system resolution, resulting in a FWHM as good as 1.35 ns. The results suggest that the coincidence window for the current PET can be reduced in order to minimize the random events and thus, achieve better image quality

  18. SHiP: a new facility with a dedicated detector for studying $\

    CERN Document Server

    Buonaura, Annarita

    2016-01-01

    SHIP is a new general purpose fixed target facility, proposed at the CERN SPS accelerator. In five years, $2\\times 10^{20}$ protons of 400 GeV/c momentum will be dumped on a Molybdenum target. A detector downstream of the target will allow a search to made for long-lived particles with masses below O(10) GeV/c$^2$ foreseen in several extensions of the Standard Model. Another dedicated detector will allow the study of active neutrino cross-sections and angular distributions. The neutrino detector consists of an emulsion target, based on the Emulsion Cloud Chamber technology fruitfully employed in the OPERA experiment. The Emulsion Cloud Chamber will be placed in a magnetic field, with the so-called Compact Emulsion Spectrometer, a few cm thick chamber for the charge and momentum measurement of hadrons. This will provide the leptonic number measurement also in the hadronic tau decay channels. The detector will be hybrid, using nuclear emulsions and electronic detectors for the time stamp of the events and the m...

  19. First Experiences of Beam Presence Detection Based on Dedicated Beam Position Monitors

    CERN Document Server

    Jalal, A; Gasior, M; Todd, B

    2011-01-01

    High intensity particle beam injection into the LHC is only permitted when a low intensity pilot beam is already circulating in the LHC. This requirement addresses some of the risks associated with high intensity injection, and is enforced by a so-called Beam Presence Flag (BPF) system which is part of the interlock chain between the LHC and its injector complex. For the 2010 LHC run, the detection of the presence of this pilot beam was implemented using the LHC Fast Beam Current Transformer (FBCT) system. However, the primary function of the FBCTs, that is reliable measurement of beam currents, did not allow the BPF system to satisfy all quality requirements of the LHC Machine Protection System (MPS). Safety requirements associated with high intensity injections triggered the development of a dedicated system, based on Beam Position Monitors (BPM). This system was meant to work first in parallel with the FBCT BPF system and eventually replace it. At the end of 2010 and in 2011, this new BP...

  20. Towards Effective Non-Invasive Brain-Computer Interfaces Dedicated to Gait Rehabilitation Systems

    Directory of Open Access Journals (Sweden)

    Thierry Castermans

    2013-12-01

    Full Text Available In the last few years, significant progress has been made in the field of walk rehabilitation. Motor cortex signals in bipedal monkeys have been interpreted to predict walk kinematics. Epidural electrical stimulation in rats and in one young paraplegic has been realized to partially restore motor control after spinal cord injury. However, these experimental trials are far from being applicable to all patients suffering from motor impairments. Therefore, it is thought that more simple rehabilitation systems are desirable in the meanwhile. The goal of this review is to describe and summarize the progress made in the development of non-invasive brain-computer interfaces dedicated to motor rehabilitation systems. In the first part, the main principles of human locomotion control are presented. The paper then focuses on the mechanisms of supra-spinal centers active during gait, including results from electroencephalography, functional brain imaging technologies [near-infrared spectroscopy (NIRS, functional magnetic resonance imaging (fMRI, positron-emission tomography (PET, single-photon emission-computed tomography (SPECT] and invasive studies. The first brain-computer interface (BCI applications to gait rehabilitation are then presented, with a discussion about the different strategies developed in the field. The challenges to raise for future systems are identified and discussed. Finally, we present some proposals to address these challenges, in order to contribute to the improvement of BCI for gait rehabilitation.

  1. The genus Romboutsia : genomic and functional characterization of novel bacteria dedicated to life in the intestinal tract

    NARCIS (Netherlands)

    Gerritsen, J.

    2015-01-01

    The genus Romboutsia: genomic and functional characterization of novel bacteria dedicated to life in the intestinal tract

    PhD thesis Jacoline Gerritsen, 2015

    Abstract

    Humans, like other mammals, are not single-species organisms, but they

  2. Could running experience on SPMD computers contribute to the architectural choices for future dedicated computers for high energy physics simulation?

    International Nuclear Information System (INIS)

    Jejcic, A.; Maillard, J.; Silva, J.; Auguin, M.; Boeri, F.

    1989-01-01

    Results obtained on a strongly coupled parallel computer are reported. They concern Monte-Carlo simulation and pattern recognition. Though the calculations were made on an experimental computer of rather low processing power, it is believed that the quoted figures could give useful indications on architectural choices for dedicated computers. (orig.)

  3. Potential land competition between open-pond microalgae production and terrestrial dedicated feedstock supply systems in the U.S.

    Energy Technology Data Exchange (ETDEWEB)

    Langholtz, Matthew H.; Coleman, Andre M.; Eaton, Laurence M.; Wigmosta, Mark S.; Hellwinckel, Chad M.; Brandt, Craig C.

    2016-08-01

    Biofuels produced from both terrestrial and algal biomass feedstocks can contribute to energy security while providing economic, environmental, and social benefits. To assess the potential for land competition between these two feedstock types in the United States, we evaluate a scenario in which 41.5 x 109 L yr-1 of second-generation biofuels are produced on pastureland, the most likely land base where both feedstock types may be deployed. This total includes 12.0 x 109 L yr-1 of biofuels from open-pond microalgae production and 29.5 x 109 L yr-1 of biofuels from terrestrial dedicated feedstock supply systems. Under these scenarios, open-pond microalgae production is projected to use 1.2 million ha of private pastureland, while terrestrial dedicated feedstock supply systems would use 14.0 million ha of private pastureland. A spatial meta-analysis indicates that potential competition for land under these scenarios would be concentrated in 110 counties, containing 1.0 and 1.7 million hectares of algal and terrestrial dedicated feedstock production, respectively. A land competition index applied to these 110 counties suggests that 38 to 59 counties could experience competition for upwards of 40% of a county’s pastureland. However, this combined 2.7 million ha represents only 2%-5% of total pastureland in the U.S., with the remaining 12.5 million ha of algal or terrestrial dedicated feedstock production on pastureland in non-competing areas.

  4. Constraints and Dedication as Drivers for Relationship Commitment: An Empirical Study in a Health-Care Context

    NARCIS (Netherlands)

    Odekerken-Schröder, G.J.; Bloemer, J.M.M.

    2002-01-01

    The objective of this study is to empirically determine the role of constraints and dedication as drivers of relationship commitment as most of the existing work is of a conceptual nature only. We assess how and to which extent these two drivers fit into the established relationships between overall

  5. A Dedicated Diversity Course or an Infusion Model? Exploring Which Strategy Is More Effective in Social Work Pedagogy

    Science.gov (United States)

    Pitner, Ronald O.; Priester, Mary Ann; Lackey, Richard; Duvall, Deborah

    2018-01-01

    The Council on Social Work Education requires schools of social work to meet diversity and social justice competencies. Many MSW programs meet these standards by having either a dedicated diversity and social justice course, or by using some form of diversity and social justice curricular infusion. The current study explored which of these…

  6. Can favorable psychosocial work conditions and high work dedication protect against the occurrence of work-related musculoskeletal disorders?

    NARCIS (Netherlands)

    Joling, C.I.; Blatter, B.M.; Ybema, J.F.; Bongers, P.M.

    2008-01-01

    Objectives. This study investigated whether work dedication and job resources are longitudinally related to work-related musculoskeletal disorders and whether job resources buffer the impact of job demands on these disorders? Methods. Data were used from a longitudinal three-phase study (2004, 2005,

  7. Role of personality in scientific advancement (dedicated to the eightieth anniversary of the birth of Lev G. Gassanov

    Directory of Open Access Journals (Sweden)

    Glushechenko E. M.

    2016-05-01

    Full Text Available The article is dedicated to Lev G. Gassanov who between 1974 and 1991 headed the "Saturn" Research Institute. Lev Gassanov was an outstanding personality, a talented leader, organizer and scholar, author of many books, scientific works and inventions, he founded a national school for the creation of a broad range of micropower electronics devices and systems.

  8. Dedicated health systems strengthening of the Global Fund to Fight AIDS, Tuberculosis, and Malaria: an analysis of grants.

    Science.gov (United States)

    Fan, Victoria Y; Tsai, Feng-Jen J; Shroff, Zubin C; Nakahara, Branden; Vargha, Nabil; Weathers, Scott

    2017-01-01

    This study aims to understand the determinants of the Global Fund to Fight AIDS, Tuberculosis, and Malaria's dedicated channel for health systems strengthening (HSS) funding across countries and to analyze their health system priorities expressed in budgets and performance indicators. We obtained publicly available data for disease-specific and HSS grants from the Global Fund over 2004-2013 prior to the new funding model. Regression analysis was employed to assess the determinants of dedicated HSS funding across 111 countries. Documents for 27 dedicated HSS grants including budgets and performance indicators were collected, and activities were analyzed by health system functions. HSS funding per capita is significantly associated with TB and HIV funding per capita, but not per capita income and health worker density. Of 27 dedicated HSS grants, 11 had line-item budgets publicly available, in which health workforce and medical products form the majority (89% or US$132 million of US$148 million) of funds. Yet these areas accounted for 41.7% (215) of total 516 performance indicators. Health worker densities were not correlated with HSS funding, despite the emphasis on health workforce in budgets and performance indicators. Priorities in health systems in line-item budgets differ from the numbers of indicators used. © The Author 2016. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  9. The roles of constraint-based and dedication-based influences on user's continued online shopping behavior.

    Science.gov (United States)

    Chang, Su-Chao; Chou, Chi-Min

    2012-11-01

    The objective of this study was to determine empirically the role of constraint-based and dedication-based influences as drivers of the intention to continue using online shopping websites. Constraint-based influences consist of two variables: trust and perceived switching costs. Dedication-based influences consist of three variables: satisfaction, perceived usefulness, and trust. The current results indicate that both constraint-based and dedication-based influences are important drivers of the intention to continue using online shopping websites. The data also shows that trust has the strongest total effect on online shoppers' intention to continue using online shopping websites. In addition, the results indicate that the antecedents of constraint-based influences, technical bonds (e.g., perceived operational competence and perceived website interactivity) and social bonds (e.g., perceived relationship investment, community building, and intimacy) have indirect positive effects on the intention to continue using online shopping websites. Based on these findings, this research suggests that online shopping websites should build constraint-based and dedication-based influences to enhance user's continued online shopping behaviors simultaneously.

  10. Could running experience on SPMD computers contribute to the architectural choices for future dedicated computers for high energy physics simulation

    International Nuclear Information System (INIS)

    Jejcic, A.; Maillard, J.; Silva, J.; Auguin, M.; Boeri, F.

    1989-01-01

    Results obtained on strongly coupled parallel computer are reported. They concern Monte-Carlo simulation and pattern recognition. Though the calculations were made on an experimental computer of rather low processing power, it is believed that the quoted figures could give useful indications on architectural choices for dedicated computers

  11. TU-EF-207-05: Dedicated Cone-beam Breast CT

    Energy Technology Data Exchange (ETDEWEB)

    Vedantham, S. [Univ. of Massachusetts Medical School (United States)

    2015-06-15

    mode due to lower photon fluence per projection. This may require fast-frame acquisition and symmetric or asymmetric pixel binning in some systems. Recent studies investigated the performance of increased conversion layer thickness for contrast-enhanced imaging of the breast in dual-energy acquisition mode. In other direct conversion detectors operating in the avalanche mode, sensitivities close to the single photon response are also explored for mammography and breast tomosynthesis. The potential advantages and challenges of this approach are described. Dedicated breast CT brings x-ray imaging of the breast to true tomographic 3D imaging. It can eliminate the tissue superposition problem and does not require physical compression of the breast. Using cone beam geometry and a flat-panel detector, several hundred projections are acquired and reconstructed to near isotropic voxels. Multiplanar reconstruction facilitates viewing the breast volume in any desired orientation. Ongoing clinical studies, the current state-of-the art, and research to advance the technology are described. Learning Objectives: To understand the ongoing developments in x-ray imaging of the breast To understand the approaches and applications of spectral mammography To understand the potential advantages of distributed x-ray source arrays for digital breast tomosynthesis To understand the ongoing developments in detector technology for digital mammography and breast tomosynthesis To understand the current state-of-the-art for dedicated cone-beam breast CT and research to advance the technology. Research collaboration with Koning Corporation.

  12. TU-EF-207-05: Dedicated Cone-beam Breast CT

    International Nuclear Information System (INIS)

    Vedantham, S.

    2015-01-01

    mode due to lower photon fluence per projection. This may require fast-frame acquisition and symmetric or asymmetric pixel binning in some systems. Recent studies investigated the performance of increased conversion layer thickness for contrast-enhanced imaging of the breast in dual-energy acquisition mode. In other direct conversion detectors operating in the avalanche mode, sensitivities close to the single photon response are also explored for mammography and breast tomosynthesis. The potential advantages and challenges of this approach are described. Dedicated breast CT brings x-ray imaging of the breast to true tomographic 3D imaging. It can eliminate the tissue superposition problem and does not require physical compression of the breast. Using cone beam geometry and a flat-panel detector, several hundred projections are acquired and reconstructed to near isotropic voxels. Multiplanar reconstruction facilitates viewing the breast volume in any desired orientation. Ongoing clinical studies, the current state-of-the art, and research to advance the technology are described. Learning Objectives: To understand the ongoing developments in x-ray imaging of the breast To understand the approaches and applications of spectral mammography To understand the potential advantages of distributed x-ray source arrays for digital breast tomosynthesis To understand the ongoing developments in detector technology for digital mammography and breast tomosynthesis To understand the current state-of-the-art for dedicated cone-beam breast CT and research to advance the technology. Research collaboration with Koning Corporation

  13. Development and optimization of a beam shaper device for a mobile dedicated IOERT accelerator

    International Nuclear Information System (INIS)

    Soriani, Antonella; Iaccarino, Giuseppe; Felici, Giuseppe; Ciccotelli, Alessia; Pinnarò, Paola; Giordano, Carolina; Benassi, Marcello; D'Andrea, Marco; Bellesi, Luca; Strigari, Lidia

    2012-01-01

    Purpose: The aim of this study was to design and build a prototype beam shaper to be used on a dedicated mobile accelerator that protects organs at risk within the radiation field and conforms the beam to the target geometry during intraoperative electron radiotherapy (IOERT). A dosimetric characterization of the beam shaper device was performed based on Monte Carlo (MC) simulations, as well as experimental data, at different energies, field sizes, and source to skin distances. Methods: A mobile light intraoperative accelerator (LIAC ® , Sordina, Italy) was used. The design of the beam shaper prototype was based on MC simulations (BEAMnrc/OMEGA and DOSXYZnrc code) for a selection of materials and thicknesses, as well as for dosimetric characterization. Percentage depth dose (PDD) and profile measurements were performed using a p-type silicon diode and a commercial water phantom, while output factors were measured using a PinPoint ion chamber in a PMMA phantom. Planar doses in planes of interest were carried out using radiochromic films (Gafchromic TM EBT and EBT2) in PMMA and in a Solid Water ® phantom. Several experimental set-ups were investigated with the beam shaper device fixed on the top of the phantom, varying both the short side of the rectangular field and the air gap between the device and the phantom surface, simulating the clinical situation. The output factors (OFs) were determined using different geometrical set-ups and energies. Results: The beam shaper prototype consists of four blades sliding alongside each other and mounted on a special support at the end of the 10 cm diameter PMMA circular applicator. Each blade is made of an upper layer of 2.6 cm of Teflon ® and a lower layer of 8 mm of stainless steel. All rectangles inscribed in a 5 cm diameter can be achieved in addition to any “squircle-shaped” field. When one side of the rectangular field is held constant and the second side is reduced, both R 50 and R max move towards the phantom

  14. Experience with dedicated ultra fast solid state cardiac gamma camera: technologist perspective

    International Nuclear Information System (INIS)

    Parab, Anil; Gaikar, Anil; Patil, Kashinath; Lele, V.

    2010-01-01

    Full text: To describe technologist perspective of working with ultra fast solid state gamma camera and comparison with conventional dual head gamma camera. Material and Methods: 900 Myocardial Perfusion scan were carried out on dedicated solid state detector cardiac camera between 1st February 2010 till 29th August 2010. 27 studies were done back to back on a conventional dual head gamma camera. In 2 cases dual head isotope imaging was done (Thallium+ 99m Tc-tetrofosmin). Rest stress protocol was used in 600 patients and stress - rest protocol was used in 300. 1:3 ratio of injected activity was maintained for both protocols (5 mCi for 1st study and 15 mCi for second study). For Rest - Stress protocol, 5 mCi of 99m Tc - Tetrofosmin was injected at rest, 40 minutes later, 5 min image was acquired on the solid state detector. Patient was then stressed. 15 mCi 99m Tc - Tetrofosmin was injected at peak stress. Images were acquired 20 minutes later for 3 minutes (total duration of study 90-100 min). For stress rest protocol, 5 mCi 99m Tc - Tetrofosmin was injected at peak stress. 5 mCi images were acquired 20 minutes later. Rest injection of 15 mCi was given 1 hour post stress injection. Rest images were acquired 40 minutes after rest injection (total duration of study 110-120 min). Results: We observed even with lesser amount activity and acquisition time of 5 min/cardiac scan it showed high sensitivity count rate over 2.2-4.7 kcps (10 times more counts than standard gamma camera). System gives better energy resolution < 7%. Better image contrast. Dual isotope imaging can be possible. Spatial resolution 4.3-4.9 mm. Excellent quality images were obtained using low activities (5 mCi/15 mCi) using 1/3rd the acquisition time compared to conventional dual head gamma camera Even in obese patients 7 mCi/21 mCi activity yielded excellent images at 1/3 rd acquisition time Quick acquisition resulted in greater patient comfort and no motion artifact also due to non rotation of

  15. Advances in 4D treatment planning for scanned particle beam therapy - report of dedicated workshops.

    Science.gov (United States)

    Bert, Christoph; Graeff, Christian; Riboldi, Marco; Nill, Simeon; Baroni, Guido; Knopf, Antje-Christin

    2014-12-01

    We report on recent progress in the field of mobile tumor treatment with scanned particle beams, as discussed in the latest editions of the 4D treatment planning workshop. The workshop series started in 2009, with about 20 people from 4 research institutes involved, all actively working on particle therapy delivery and development. The first workshop resulted in a summary of recommendations for the treatment of mobile targets, along with a list of requirements to apply these guidelines clinically. The increased interest in the treatment of mobile tumors led to a continuously growing number of attendees: the 2012 edition counted more than 60 participants from 20 institutions and commercial vendors. The focus of research discussions among workshop participants progressively moved from 4D treatment planning to complete 4D treatments, aiming at effective and safe treatment delivery. Current research perspectives on 4D treatments include all critical aspects of time resolved delivery, such as in-room imaging, motion detection, beam application, and quality assurance techniques. This was motivated by the start of first clinical treatments of hepato cellular tumors with a scanned particle beam, relying on gating or abdominal compression for motion mitigation. Up to date research activities emphasize significant efforts in investigating advanced motion mitigation techniques, with a specific interest in the development of dedicated tools for experimental validation. Potential improvements will be made possible in the near future through 4D optimized treatment plans that require upgrades of the currently established therapy control systems for time resolved delivery. But since also these novel optimization techniques rely on the validity of the 4DCT, research focusing on alternative 4D imaging technique, such as MRI based 4DCT generation will continue.

  16. Evaluation of a dedicated MDCT protocol using iterative image reconstruction after cervical spine trauma.

    Science.gov (United States)

    Geyer, L L; Körner, M; Hempel, R; Deak, Z; Mueck, F G; Linsenmaier, U; Reiser, M F; Wirth, S

    2013-07-01

    To evaluate radiation exposure for 64-row computed tomography (CT) of the cervical spine comparing two optimized protocols using filtered back projection (FBP) and adaptive statistical iterative reconstruction (ASIR), respectively. Sixty-seven studies using FBP (scanner 1) were retrospectively compared with 80 studies using ASIR (scanner 2). The key scanning parameters were identical (120 kV dose modulation, 64 × 0.625 mm collimation, pitch 0.531:1). In protocol 2, the noise index (NI) was increased from 5 to 25, and ASIR and the high-definition (HD) mode were used. The scan length, CT dose index (CTDI), and dose-length product (DLP) were recorded. The image quality was analysed subjectively by using a three-point scale (0; 1; 2), and objectively by using a region of interest (ROI) analysis. Mann-Whitney U and Wilcoxon's test were used. In the FBP group, the mean CTDI was 21.43 mGy, mean scan length 186.3 mm, and mean DLP 441.15 mGy cm. In the ASIR group, the mean CTDI was 9.57 mGy, mean scan length 195.21 mm, and mean DLP 204.23 mGy cm. The differences were significant for CTDI and DLP (p 0.05). The estimated mean effective dose decreased from 2.38 mSv (FBP) to 1.10 mSv (ASIR). The radiation dose of 64-row MDCT can be reduced to a level comparable to plain radiography without loss of subjective image quality by implementation of ASIR in a dedicated cervical spine trauma protocol. These results might contribute to an improved relative risk-to-benefit ratio and support the justification of CT as a first-line imaging tool to evaluate cervical spine trauma. Copyright © 2013 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

  17. THE POTENTIAL FOR NEUTRINO PHYSICS AT MUON COLLIDERS AND DEDICATED HIGH CURRENT MUON STORAGE RINGS

    International Nuclear Information System (INIS)

    BIGI, I.; BOLTON, T.; FORMAGGIO, J.; HARRIS, D.; MORFIN, J.; SPENTZOURIS, P.; YU, J.; KAYSER, B.; KING, B.J.; MCFARLAND, K.; PETROV, A.; SCHELLMAN, H.; VELASCO, M.; SHROCK, R.

    2000-01-01

    Conceptual design studies are underway for both muon colliders and high-current non-colliding muon storage rings that have the potential to become the first true neutrino factories. Muon decays in long straight sections of the storage rings would produce uniquely intense and precisely characterized two-component neutrino beams--muon neutrinos plus electron antineutrinos from negative muon decays and electron neutrinos plus muon antineutrinos from positive muons. This article presents a long-term overview of the prospects for these facilities to greatly extend the capabilities for accelerator-based neutrino physics studies for both high rate and long baseline neutrino experiments. As the first major physics topic, recent experimental results involving neutrino oscillations have motivated a vigorous design effort towards dedicated neutrino factories that would store muon beams of energies 50 GeV or below. These facilities hold the promise of neutrino oscillation experiments with baselines up to intercontinental distances and utilizing well understood beams that contain, for the first time, a substantial component of multi-GeV electron-flavored neutrinos. In deference to the active and fast-moving nature of neutrino oscillation studies, the discussion of long baseline physics at neutrino factories has been limited to a concise general overview of the relevant theory, detector technologies, beam properties, experimental goals and potential physics capabilities. The remainder of the article is devoted to the complementary high rate neutrino experiments that would study neutrino-nucleon and neutrino-electron scattering and would be performed at high performance detectors placed as close as is practical to the neutrino production straight section of muon storage rings in order to exploit beams with transverse dimensions as small as a few tens of centimeters

  18. Opportunistic Computing with Lobster: Lessons Learned from Scaling up to 25k Non-Dedicated Cores

    Science.gov (United States)

    Wolf, Matthias; Woodard, Anna; Li, Wenzhao; Hurtado Anampa, Kenyi; Yannakopoulos, Anna; Tovar, Benjamin; Donnelly, Patrick; Brenner, Paul; Lannon, Kevin; Hildreth, Mike; Thain, Douglas

    2017-10-01

    We previously described Lobster, a workflow management tool for exploiting volatile opportunistic computing resources for computation in HEP. We will discuss the various challenges that have been encountered while scaling up the simultaneous CPU core utilization and the software improvements required to overcome these challenges. Categories: Workflows can now be divided into categories based on their required system resources. This allows the batch queueing system to optimize assignment of tasks to nodes with the appropriate capabilities. Within each category, limits can be specified for the number of running jobs to regulate the utilization of communication bandwidth. System resource specifications for a task category can now be modified while a project is running, avoiding the need to restart the project if resource requirements differ from the initial estimates. Lobster now implements time limits on each task category to voluntarily terminate tasks. This allows partially completed work to be recovered. Workflow dependency specification: One workflow often requires data from other workflows as input. Rather than waiting for earlier workflows to be completed before beginning later ones, Lobster now allows dependent tasks to begin as soon as sufficient input data has accumulated. Resource monitoring: Lobster utilizes a new capability in Work Queue to monitor the system resources each task requires in order to identify bottlenecks and optimally assign tasks. The capability of the Lobster opportunistic workflow management system for HEP computation has been significantly increased. We have demonstrated efficient utilization of 25 000 non-dedicated cores and achieved a data input rate of 30 Gb/s and an output rate of 500GB/h. This has required new capabilities in task categorization, workflow dependency specification, and resource monitoring.

  19. A Dedicated Space Observatory For Time-domain Solar System Science

    Science.gov (United States)

    Wong, Michael H.; Ádámkovics, M.; Benecchi, S.; Bjoraker, G.; Clarke, J. T.; de Pater, I.; Hendrix, A. R.; Marchis, F.; McGrath, M.; Noll, K.; Rages, K. A.; Retherford, K.; Smith, E. H.; Strange, N. J.

    2009-09-01

    Time-variable phenomena with scales ranging from minutes to decades have led to a large fraction of recent advances in many aspects of solar system science. We present the scientific motivation for a dedicated space observatory for solar system science. This facility will ideally conduct repeated imaging and spectroscopic observations over a period of 10 years or more. It will execute a selection of long-term projects with interleaved scheduling, resulting in the acquisition of data sets with consistent calibration, long baselines, and optimized sampling intervals. A sparse aperture telescope would be an ideal configuration for the mission, trading decreased sensitivity for reduced payload mass, while preserving spatial resolution. Ultraviolet capability is essential, especially once the Hubble Space Telescope retires. Specific investigations will include volcanism and cryovolcanism (on targets including Io, Titan, Venus, Mars, and Enceladus); zonal flow, vortices, and storm evolution on the giant planets; seasonal cycles in planetary atmospheres; mutual events and orbit determination of multiple small solar system bodies; auroral activity and solar wind interactions; and cometary evolution. The mission will produce a wealth of data products--such as multi-year time-lapse movies of planetary atmospheres--with significant education and public outreach potential. Existing and planned ground- and space-based facilities are not suitable for these time-domain optimized planetary dynamics studies for numerous reasons, including: oversubscription by astrophysical users, field-of-regard limitations, sensitive detector saturation limits that preclude bright planetary targets, and limited mission duration. The abstract author list is a preliminary group of scientists who have shown interest in prior presentations on this topic; interested parties may contact the lead author by 1 September to sign the associated Planetary Science Decadal Survey white paper or by 1 October to

  20. Characteristics of a dedicated linear accelerator-based stereotactic radiosurgery-radiotherapy unit

    International Nuclear Information System (INIS)

    Das, Indra J.; Downes, M. Beverly; Corn, Benjamin W.; Curran, Walter J.; Werner-Wasik, M.; Andrews, David W.

    1996-01-01

    A stereotactic radiosurgery and radiotherapy (SRS/SRT) system on a dedicated Varian Clinac-600SR linear accelerator with Brown-Roberts-Wells and Gill-Thomas-Cosman relocatable frames along with the Radionics (RSA) planning system is evaluated. The Clinac-600SR has a single 6-MV beam with the same beam characteristics as that of the mother unit, the Clinac-600C. The primary collimator is a fixed cone projecting to a 10-cm diameter at isocenter. The secondary collimator is a heavily shielded cylindrical collimator attached to the face plate of the primary collimator. The tertiary collimation consists of the actual treatment cones. The cone sizes vary from 12.5 to 40.0 mm diameter. The mechanical stability of the entire system was verified. The variations in isocenter position with table, gantry, and collimator rotation were found to be <0.5 mm with a compounded accuracy of ≤ 1.0 mm. The radiation leakage under the cones was < 1% measured at a depth of 5 cm in a phantom. The beam profiles of all cones in the x and y directions were within ±0.5 mm and match with the physical size of the cone. The dosimetric data such as tissue maximum ratio, off-axis ratio, and cone factor were taken using film, diamond detector, and ion chambers. The mechanical and dosimetric characteristics including dose linearity of this unit are presented and found to be suitable for SRS/SRT. The difficulty in absolute dose measurement for small cone is discussed

  1. X-ray scatter correction method for dedicated breast computed tomography: improvements and initial patient testing

    International Nuclear Information System (INIS)

    Ramamurthy, Senthil; D’Orsi, Carl J; Sechopoulos, Ioannis

    2016-01-01

    A previously proposed x-ray scatter correction method for dedicated breast computed tomography was further developed and implemented so as to allow for initial patient testing. The method involves the acquisition of a complete second set of breast CT projections covering 360° with a perforated tungsten plate in the path of the x-ray beam. To make patient testing feasible, a wirelessly controlled electronic positioner for the tungsten plate was designed and added to a breast CT system. Other improvements to the algorithm were implemented, including automated exclusion of non-valid primary estimate points and the use of a different approximation method to estimate the full scatter signal. To evaluate the effectiveness of the algorithm, evaluation of the resulting image quality was performed with a breast phantom and with nine patient images. The improvements in the algorithm resulted in the avoidance of introduction of artifacts, especially at the object borders, which was an issue in the previous implementation in some cases. Both contrast, in terms of signal difference and signal difference-to-noise ratio were improved with the proposed method, as opposed to with the correction algorithm incorporated in the system, which does not recover contrast. Patient image evaluation also showed enhanced contrast, better cupping correction, and more consistent voxel values for the different tissues. The algorithm also reduces artifacts present in reconstructions of non-regularly shaped breasts. With the implemented hardware and software improvements, the proposed method can be reliably used during patient breast CT imaging, resulting in improvement of image quality, no introduction of artifacts, and in some cases reduction of artifacts already present. The impact of the algorithm on actual clinical performance for detection, diagnosis and other clinical tasks in breast imaging remains to be evaluated. (paper)

  2. First experiences of beam presence detection based on dedicated beam position monitors

    International Nuclear Information System (INIS)

    Jalal, A.; Gabourin, S.; Gasior, M.; Todd, B.

    2012-01-01

    High intensity particle beam injection into the LHC is only permitted when a low intensity pilot beam is already circulating in the LHC. This requirement addresses some of the risks associated with high intensity injection, and is enforced by a so-called Beam Presence Flag (BPF) system which is part of the interlock chain between the LHC and its injector complex. For the 2010 LHC run, the detection of the presence of this pilot beam was implemented using the LHC Fast Beam Current Transformer (FBCT) system. However, the primary function of the FBCTs, that is reliable measurement of beam currents, did not allow the BPF system to satisfy all quality requirements of the LHC Machine Protection System (MPS). Safety requirements associated with high intensity injections triggered the development of a dedicated system, based on Beam Position Monitors (BPM). This system was meant to work first in parallel with the FBCT BPF system and eventually replace it. At the end of 2010 and in 2011, this new BPF implementation based on BPMs was designed, built, tested and deployed. This paper reviews both the FBCT and BPM implementation of the BPF system, outlining the changes during the transition period. The paper briefly describes the testing methods, focuses on the results obtained from the tests performed during the end of 2010 LHC run and shows the changes made for the BPM BPF system deployment in LHC in 2011. Whilst the system has been proved to work with a threshold of 6*10 8 charges, it has been implemented with a threshold of 2*10 9 charges to protect the LHC. (authors)

  3. A dedicated beam line for Rutherford backscattering analysis at IFIN-HH cyclotron

    International Nuclear Information System (INIS)

    Ivanov, E. A.; Dudu, D.; Plostinaru, D.; Catana, D.; Vata, I.

    2003-01-01

    Rutherford back-scattering technique (RBS) is an analytical tool that uses elastic scattering of 1-5 MeV charged particles for analysis of the surface and the outer few micrometers of solids. IFIN-HH RBS system consists of the U-120 Cyclotron, a dedicated beam line and a scattering chamber with sample manipulators and particle detectors. In our RBS system the samples are bombarded with 2-5 alpha particles accelerated by U-120 Cyclotron (in 3-rd subharmonic regime) while the scattered particles are detected by a surface barrier detector. The signal from the detector is processed by common nuclear electronics and the particle energy spectra are stored in a computer based multichannel analyser. The data evaluation is accomplished using standard procedures and computer codes. The necessary vacuum inside chamber is obtained with an oil-free turbo pump. The beam spot dimension on the target is 1x1 mm. The standard measurement are done at Θ = 165 angle. The samples are electrically insulated and can be rotated around a vertical axis. The advantage of the RBS technique lies in the quantitative analysis of major and minor constituents lying in the first 0.5 to 2.0 micrometers of a material. Depending on the sample structure and composition, the detection limits vary from 10 11 to 10 15 at. cm -2 for heavy and light elements, respectively. The depth distribution of constituents can be reconstructed with a depth resolution of 10-20 nm. The RBS technique is non-destructive since the erosion and the radiation degradation of the sample material by the particle impact is negligible. The most extensive use of the RBS technique is in the field of electronic and optical materials, special coatings and in the study of various physico-chemical processes on the solid surfaces. (authors)

  4. Astronomers Without Borders: An IYA2009 Organization Node Dedicated to Connecting Groups Worldwide

    Science.gov (United States)

    Simmons, Michael

    2008-05-01

    Astronomers Without Borders (AWB) is a new global organizational and IYA2009 Organizational Node dedicated to furthering understanding and goodwill across national and cultural boundaries using the universal appeal of astronomy, a common language spoken by all those who share an interest in the sky. It is a universal interest that connects us. The AWB network of Affiliates will bring together up to 1000 astronomy clubs, magazines and other organizations involved in astronomy. Regional Coordinators work within their own regions - based on common language and culture rather than political or geographic boundaries - to best implement AWB's goals, involve the region's participants and bring in new ideas based on local culture and tradition. Participation is free for all Affiliates. The AWB web site is the center for the network of Affiliates. This Community Center is the global meeting place where Affiliates interact. Forums, galleries and more interactive technologies will be used. Sharing Telescopes and Resources (STAR) gathers both surplus and new telescopes and other equipment in developed countries and donates them to clubs in undeveloped countries. Follow-up programs are meant to ensure the best and widest use of the telescope in the destination country, and to maintain a relationship between donors and recipients. The World at Night (TWAN) has been designated as a Special IYA2009 Project. TWAN's specialty photographers create wide-angle images of the night sky in important natural and historic settings around the world that dramatically demonstrate the universal nature and appeal of the night sky. A web site, major exhibitions and more are planned for IYA2009. Astro-tourism has been proposed by several Affiliates. This program will draw on existing facilities and experiences, primarily from the long-established solar eclipse tour industry. AWB is meant to continue and grow for many years beyond the end of IYA2009.

  5. Novel carotenoid cleavage dioxygenase catalyzes the first dedicated step in saffron crocin biosynthesis

    KAUST Repository

    Frusciante, Sarah; Diretto, Gianfranco; Bruno, Mark; Ferrante, Paola; Pietrella, Marco; Prado-Cabrero, Alfonso; Rubio-Moraga, Á ngela L.; Beyer, Peter D.; Gó mez-Gó mez, Lourdes; Al-Babili, Salim; Giuliano, Giovanni

    2014-01-01

    Crocus sativus stigmas are the source of the saffron spice and accumulate the apocarotenoids crocetin, crocins, picrocrocin, and safranal, responsible for its color, taste, and aroma. Through deep transcriptome sequencing, we identified a novel dioxygenase, carotenoid cleavage dioxygenase 2 (CCD2), expressed early during stigma development and closely related to, but distinct from, the CCD1 dioxygenase family. CCD2 is the only identified member of a novel CCD clade, presents the structural features of a bona fide CCD, and is able to cleave zeaxanthin, the presumed precursor of saffron apocarotenoids, both in Escherichia coli and in maize endosperm. The cleavage products, identified through high-resolution mass spectrometry and comigration with authentic standards, are crocetin dialdehyde and crocetin, respectively. In vitro assays show that CCD2 cleaves sequentially the 7,8 and 7′,8′ double bonds adjacent to a 3-OH-β-ionone ring and that the conversion of zeaxanthin to crocetin dialdehyde proceeds via the C30 intermediate 3-OH-β-apo-8′-carotenal. In contrast, zeaxanthin cleavage dioxygenase (ZCD), an enzyme previously claimed to mediate crocetin formation, did not cleave zeaxanthin or 3-OH-β-apo-8′-carotenal in the test systems used. Sequence comparison and structure prediction suggest that ZCD is an N-truncated CCD4 form, lacking one blade of the β-propeller structure conserved in all CCDs. These results constitute strong evidence that CCD2 catalyzes the first dedicated step in crocin biosynthesis. Similar to CCD1, CCD2 has a cytoplasmic localization, suggesting that it may cleave carotenoids localized in the chromoplast outer envelope.

  6. Optimization of a dedicated bio-imaging beamline at the European X-ray FEL

    Energy Technology Data Exchange (ETDEWEB)

    Geloni, Gianluca [European XFEL GmbH, Hamburg (Germany); Kocharyan, Vitali; Saldin, Evgeni [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2012-09-15

    We recently proposed a basic concept for design and layout of the undulator source for a dedicated bio-imaging beamline at the European XFEL. The goal of the optimized scheme proposed here is to enable experimental simplification and performance improvement. The core of the scheme is composed by soft and hard X-ray self-seeding setups. Based on the use of an improved design for both monochromators it is possible to increase the design electron energy up to 17.5 GeV in photon energy range between 2 keV and 13 keV, which is the most preferable for life science experiments. An advantage of operating at such high electron energy is the increase of the X-ray output peak power. Another advantage is that 17.5 GeV is the preferred operation energy for SASE1 and SASE2 beamline users. Since it will be necessary to run all the XFEL lines at the same electron energy, this choice will reduce the interference with other undulator lines and increase the total amount of scheduled beam time. In this work we also propose a study of the performance of the self-seeding scheme accounting for spatiotemporal coupling caused by the use of a single crystal monochromator. Our analysis indicates that this distortion is easily suppressed by the right choice of diamond crystal planes and that the proposed undulator source yields about the same performance as in the case for a X-ray seed pulse with no coupling. Simulations show that the FEL power reaches 2 TW in the 3 keV-5 keV photon energy range, which is the most preferable for single biomolecule imaging.

  7. The MWA archive infrastructure: archiving terabytes of data over dedicated WAN connections

    Science.gov (United States)

    Wicenec, Andreas; Pallot, Dave; Checcucci, Alessio; Kitaeff, Slava; Vinsen, Kevin; Wu, Chen

    2012-09-01

    The Murchison Wide Field Array (MWA) is being upgraded from 32 tiles to 128 tiles of 16 dual-polarization dipole antennas. In the course of this project the software and the data infrastructure are also undergoing a major overhaul in order to cope with a more continuous and remote operational model; and the substantial increase in data rate (400 MB/s from the correlator plus 160 MB/s from the real time imaging pipeline). During the course of 2012/13 the data collected by the MWA will be transported via a dedicated 40 Gbit WAN network link between the Murchison Radio Observatory (MRO) and Perth (700 km). However, this network will not be available for some time; and until then, the data will be transported using disk arrays instead. Once in Perth, the data will be ingested into a tape library. The archiving process itself consists of various steps executed either at the MRO site or in Perth, and makes use of a modied version of the archiving system from the Atacama Large Millimeter Array (ALMA). This includes the extraction of meta-data from the original raw data and the ingestion and generation of the appropriate data links for the MWA archive. The MWA correlator generates a collection of small les all belonging to the same observation. In order to optimise the network transfer and the storage of those les they are transparently packed into larger containers at the MRO site and subsequently handled as one big le. This paper describes the setup of the MWA archiving infrastructure.

  8. Analysis of mice tumor models using dynamic MRI data and a dedicated software platform

    Energy Technology Data Exchange (ETDEWEB)

    Alfke, H.; Maurer, E.; Klose, K.J. [Philipps Univ. Marburg (Germany). Dept. of Radiology; Kohle, S.; Rascher-Friesenhausen, R.; Behrens, S.; Peitgen, H.O. [MeVis - Center for Medical Diagnostic Systems and Visualization, Bremen (Germany); Celik, I. [Philipps Univ. Marburg (Germany). Inst. for Theoretical Surgery; Heverhagen, J.T. [Philipps Univ. Marburg (Germany). Dept. of Radiology; Ohio State Univ., Columbus (United States). Dept. of Radiology

    2004-09-01

    Purpose: To implement a software platform (DynaVision) dedicated to analyze data from functional imaging of tumors with different mathematical approaches, and to test the software platform in pancreatic carcinoma xenografts in mice with severe combined immunodeficiency disease (SCID). Materials and Methods: A software program was developed for extraction and visualization of tissue perfusion parameters from dynamic contrast-enhanced images. This includes regional parameter calculation from enhancement curves, parametric images (e.g., blood flow), animation, 3D visualization, two-compartment modeling a mode for comparing different datasets (e.g., therapy monitoring), and motion correction. We analyzed xenograft tumors from two pancreatic carcinoma cell lines (B x PC3 and ASPC1) implanted in 14 SCID mice after injection of Gd-DTPA into the tail vein. These data were correlated with histopathological findings. Results: Image analysis was completed in approximately 15 minutes per data set. The possibility of drawing and editing ROIs within the whole data set makes it easy to obtain quantitative data from the intensity-time curves. In one animal, motion artifacts reduced the image quality to a greater extent but data analysis was still possible after motion correction. Dynamic MRI of mice tumor models revealed a highly heterogeneous distribution of the contrast-enhancement curves and derived parameters, which correlated with differences in histopathology. ASPc1 tumors showed a more hypervascular type of curves with faster and higher signal enhancement rate (wash-in) and a faster signal decrease (wash-out). BXPC3 tumors showed a more hypovascular type with slower wash-in and wash-out. This correlated with the biological properties of the tumors. (orig.)

  9. Analysis of mice tumor models using dynamic MRI data and a dedicated software platform

    International Nuclear Information System (INIS)

    Alfke, H.; Maurer, E.; Klose, K.J.; Celik, I.; Heverhagen, J.T.; Ohio State Univ., Columbus

    2004-01-01

    Purpose: To implement a software platform (DynaVision) dedicated to analyze data from functional imaging of tumors with different mathematical approaches, and to test the software platform in pancreatic carcinoma xenografts in mice with severe combined immunodeficiency disease (SCID). Materials and Methods: A software program was developed for extraction and visualization of tissue perfusion parameters from dynamic contrast-enhanced images. This includes regional parameter calculation from enhancement curves, parametric images (e.g., blood flow), animation, 3D visualization, two-compartment modeling a mode for comparing different datasets (e.g., therapy monitoring), and motion correction. We analyzed xenograft tumors from two pancreatic carcinoma cell lines (B x PC3 and ASPC1) implanted in 14 SCID mice after injection of Gd-DTPA into the tail vein. These data were correlated with histopathological findings. Results: Image analysis was completed in approximately 15 minutes per data set. The possibility of drawing and editing ROIs within the whole data set makes it easy to obtain quantitative data from the intensity-time curves. In one animal, motion artifacts reduced the image quality to a greater extent but data analysis was still possible after motion correction. Dynamic MRI of mice tumor models revealed a highly heterogeneous distribution of the contrast-enhancement curves and derived parameters, which correlated with differences in histopathology. ASPc1 tumors showed a more hypervascular type of curves with faster and higher signal enhancement rate (wash-in) and a faster signal decrease (wash-out). BXPC3 tumors showed a more hypovascular type with slower wash-in and wash-out. This correlated with the biological properties of the tumors. (orig.)

  10. WE-FG-207A-00: Advances in Dedicated Breast CT

    International Nuclear Information System (INIS)

    2016-01-01

    Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent. Its sensitivity, especially in dense breasts, is low due to overlapping tissue and the fact that normal breast tissue, benign lesions and breast cancers all have similar “densities”, making lesion detection more difficult. We ideally need 3-D imaging for imaging the 3-D breast. MRI is 3-D, whole breast ultrasound is 3-D, digital breast tomosynthesis is called 3-D but is really “pseudo 3-D” due to poor resolution along the depth-direction. Also, and importantly, we need to be able to administer intravenous contrast agents for optimal imaging, similar to other organ systems in the body. Dedicated breast CT allows for 3-D imaging of the uncompressed breast. In current designs, the patient is positioned prone on the table and the breast is pendant through an aperture and the scan takes approximately 10 seconds [O’Connell et al., AJR 195: 496–509, 2010]. Almost on the heels of the invention of CT itself, work began on the development of dedicated breast CT. These early breast CT systems were used in clinical trials and the results from comparative performance evaluation of breast CT and mammography for 1625 subjects were reported in 1980 [Chang et al., Cancer 46: 939–46, 1980]. However, the technological limitations at that time stymied clinical translation for decades. Subsequent to the landmark article in 2001 [Boone et al., Radiology 221: 657–67, 2001] that demonstrated the potential feasibility in terms of radiation dose, multiple research groups are actively

  11. WE-FG-207A-01: Introduction to Dedicated Breast CT - Early Studies

    International Nuclear Information System (INIS)

    Vedantham, S.

    2016-01-01

    Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent. Its sensitivity, especially in dense breasts, is low due to overlapping tissue and the fact that normal breast tissue, benign lesions and breast cancers all have similar “densities”, making lesion detection more difficult. We ideally need 3-D imaging for imaging the 3-D breast. MRI is 3-D, whole breast ultrasound is 3-D, digital breast tomosynthesis is called 3-D but is really “pseudo 3-D” due to poor resolution along the depth-direction. Also, and importantly, we need to be able to administer intravenous contrast agents for optimal imaging, similar to other organ systems in the body. Dedicated breast CT allows for 3-D imaging of the uncompressed breast. In current designs, the patient is positioned prone on the table and the breast is pendant through an aperture and the scan takes approximately 10 seconds [O’Connell et al., AJR 195: 496–509, 2010]. Almost on the heels of the invention of CT itself, work began on the development of dedicated breast CT. These early breast CT systems were used in clinical trials and the results from comparative performance evaluation of breast CT and mammography for 1625 subjects were reported in 1980 [Chang et al., Cancer 46: 939–46, 1980]. However, the technological limitations at that time stymied clinical translation for decades. Subsequent to the landmark article in 2001 [Boone et al., Radiology 221: 657–67, 2001] that demonstrated the potential feasibility in terms of radiation dose, multiple research groups are actively

  12. Multidisciplinary Team Contributions Within a Dedicated Outpatient Palliative Radiotherapy Clinic: A Prospective Descriptive Study

    International Nuclear Information System (INIS)

    Pituskin, Edith; Fairchild, Alysa; Dutka, Jennifer; Gagnon, Lori; Driga, Amy; Tachynski, Patty; Borschneck, Jo-Ann; Ghosh, Sunita

    2010-01-01

    Purpose: Patients with bone metastases may experience pain, fatigue, and decreased mobility. Multiple medications for analgesia are often required, each with attendant side effects. Although palliative-intent radiotherapy (RT) is effective in decreasing pain, additional supportive care interventions may be overlooked. Our objective was to describe the feasibility of multidisciplinary assessment of patients with symptomatic bone metastases attending a dedicated outpatient palliative RT clinic. Methods and Materials: Consecutive patients referred for RT for painful bone metastases were screened for symptoms and needs relevant to their medications, nutritional intake, activities of daily living, and psychosocial and spiritual concerns from January 1 to December 31, 2007. Consultations by appropriate team members and resulting recommendations were collected prospectively. Patients who received RT were contacted by telephone 4 weeks later to assess symptom outcomes. Results: A total of 106 clinic visits by 82 individual patients occurred. As determined by screening form responses, the clinical Pharmacist, Occupational Therapist, Registered Dietician and Social Worker were consulted to provide assessments and recommendations within the time constraints presented by 1-day palliative RT delivery. In addition to pain relief, significant improvements in tiredness, depression, anxiety, drowsiness and overall well-being were reported at 4 weeks. Conclusions: Systematic screening of this population revealed previously unmet needs, addressed in the form of custom verbal and written recommendations. Multidisciplinary assessment is associated with a high number of recommendations and decreased symptom distress. Our findings lend strong support to the routine assessment by multiple supportive care professionals for patients with advanced cancer being considered for palliative RT.

  13. Impact of implementing an exclusively dedicated respiratory isolation room in a Brazilian tertiary emergency department.

    Science.gov (United States)

    Lobo, Rômulo Rebouças; Borges, Marcos Carvalho; Neves, Fábio Fernandes; Vidal de Moura Negrini, Bento; Colleto, Francisco Antonio; Romeo Boullosa, José Luiz; Camila de Miranda Cardoso, Maria; Pazin-Filho, Antonio

    2011-09-01

    Occupational risk due to airborne disease challenges healthcare institutions. Environmental measures are effective but their cost-effectiveness is still debatable and most of the capacity planning is based on occupational rates. Better indices to plan and evaluate capacity are needed. To evaluate the impact of installing an exclusively dedicated respiratory isolation room (EDRIR) in a tertiary emergency department (ED) determined by a time-to-reach-facility method. A group of patients in need of respiratory isolation were first identified--group I (2004; 29 patients; 44.1±3.4 years) and the occupational rate and time intervals (arrival to diagnosis, diagnosis to respiratory isolation indication and indication to effective isolation) were determined and it was estimated that adding an EDRIR would have a significant impact over the time to isolation. After implementing the EDRIR, a second group of patients was gathered in the same period of the year--group II (2007; 50 patients; 43.4±1.8 years) and demographic and functional parameters were recorded to evaluate time to isolation. Cox proportional hazard models adjusted for age, gender and inhospital respiratory isolation room availability were obtained. Implementing an EDRIR decreased the time from arrival to indication of respiratory isolation (27.5±9.3 × 3.7±2.0; p=0.0180) and from indication to effective respiratory isolation (13.3±3.0 × 2.94±1.06; p=0.003) but not the respiratory isolation duration and total hospital stay. The impact on crude isolation rates was very significant (8.9 × 75.4/100.000 patients; p<0.001). The HR for effective respiratory isolation was 26.8 (95% CI 7.42 to 96.9) p<0.001 greater for 2007. Implementing an EDRIR in a tertiary ED significantly reduced the time to respiratory isolation.

  14. Supermassive Black Holes and Their Host Galaxies. I. Bulge Luminosities from Dedicated Near-infrared Data

    Science.gov (United States)

    Läsker, Ronald; Ferrarese, Laura; van de Ven, Glenn

    2014-01-01

    In an effort to secure, refine, and supplement the relation between central supermassive black hole masses, M •, and the bulge luminosities of their host galaxies, L bul, we obtained deep, high spatial resolution K-band images of 35 nearby galaxies with securely measured M •, using the wide-field WIRCam imager at the Canada-France-Hawaii-Telescope. A dedicated data reduction and sky subtraction strategy was adopted to estimate the brightness and structure of the sky, a critical step when tracing the light distribution of extended objects in the near-infrared. From the final image product, bulge and total magnitudes were extracted via two-dimensional profile fitting. As a first order approximation, all galaxies were modeled using a simple Sérsic-bulge+exponential-disk decomposition. However, we found that such models did not adequately describe the structure that we observed in a large fraction of our sample galaxies which often include cores, bars, nuclei, inner disks, spiral arms, rings, and envelopes. In such cases, we adopted profile modifications and/or more complex models with additional components. The derived bulge magnitudes are very sensitive to the details and number of components used in the models, although total magnitudes remain almost unaffected. Usually, but not always, the luminosities and sizes of the bulges are overestimated when a simple bulge+disk decomposition is adopted in lieu of a more complex model. Furthermore, we found that some spheroids are not well fit when the ellipticity of the Sérsic model is held fixed. This paper presents the details of the image processing and analysis, while we discuss how model-induced biases and systematics in bulge magnitudes impact the M •-L bul relation in a companion paper.

  15. Novel carotenoid cleavage dioxygenase catalyzes the first dedicated step in saffron crocin biosynthesis

    KAUST Repository

    Frusciante, Sarah

    2014-08-05

    Crocus sativus stigmas are the source of the saffron spice and accumulate the apocarotenoids crocetin, crocins, picrocrocin, and safranal, responsible for its color, taste, and aroma. Through deep transcriptome sequencing, we identified a novel dioxygenase, carotenoid cleavage dioxygenase 2 (CCD2), expressed early during stigma development and closely related to, but distinct from, the CCD1 dioxygenase family. CCD2 is the only identified member of a novel CCD clade, presents the structural features of a bona fide CCD, and is able to cleave zeaxanthin, the presumed precursor of saffron apocarotenoids, both in Escherichia coli and in maize endosperm. The cleavage products, identified through high-resolution mass spectrometry and comigration with authentic standards, are crocetin dialdehyde and crocetin, respectively. In vitro assays show that CCD2 cleaves sequentially the 7,8 and 7′,8′ double bonds adjacent to a 3-OH-β-ionone ring and that the conversion of zeaxanthin to crocetin dialdehyde proceeds via the C30 intermediate 3-OH-β-apo-8′-carotenal. In contrast, zeaxanthin cleavage dioxygenase (ZCD), an enzyme previously claimed to mediate crocetin formation, did not cleave zeaxanthin or 3-OH-β-apo-8′-carotenal in the test systems used. Sequence comparison and structure prediction suggest that ZCD is an N-truncated CCD4 form, lacking one blade of the β-propeller structure conserved in all CCDs. These results constitute strong evidence that CCD2 catalyzes the first dedicated step in crocin biosynthesis. Similar to CCD1, CCD2 has a cytoplasmic localization, suggesting that it may cleave carotenoids localized in the chromoplast outer envelope.

  16. Characterization of the first RF coil dedicated to 1.5 T MR guided radiotherapy

    Science.gov (United States)

    Hoogcarspel, Stan J.; Zijlema, Stefan E.; Tijssen, Rob H. N.; Kerkmeijer, Linda G. W.; Jürgenliemk-Schulz, Ina M.; Lagendijk, Jan J. W.; Raaymakers, Bas W.

    2018-01-01

    The purpose of this study is to investigate the attenuation characteristics of a novel radiofrequency (RF) coil, which is the first coil that is solely dedicated to MR guided radiotherapy with a 1.5 T MR-linac. Additionally, we investigated the impact of the treatment beam on the MRI performance of this RF coil. First, the attenuation characteristics of the RF coil were characterized. Second, we investigated the impact of the treatment beam on the MRI performance of the RF coil. We additionally demonstrated the ability of the anterior coil to attenuate returning electrons and thereby reducing the dose to the skin at the distal side of the treatment beam. Intensity modulated radiation therapy simulation of a clinically viable treatment plan for spinal bone metastasis shows a decrease of the dose to the planned tumor volume of 1.8% as a result of the MR coil around the patient. Ionization chamber and film measurements show that the anterior and posterior coil attenuate the beam homogeneously by 0.4% and 2.2%, respectively. The impact of the radiation resulted in a slight drop of the time-course signal-to-noise ratio and was dependent on imaging parameters. However, we could not observe any image artifacts resulting from this irradiation in any situation. In conclusion, the investigated MR-coil can be utilized for treatments with the 1.5 T-linac system. However, there is still room for improvement when considering both the dosimetric and imaging performance of the coil.

  17. Getting it RITE: Impact of a Dedicated Hospital Medicine Curriculum for Residents.

    Science.gov (United States)

    Lin, Doris; Shah, Chirayu; Campbell, Steffanie; Bates, Jeffrey T; Lescinskas, Erica

    2018-01-01

    The goal of this study was to improve resident confidence in inpatient care and knowledge in hospital medicine topics with a newly developed rotation and curriculum called the Resident Inpatient Training Experience. This study was a prospective observational study completed by postgraduate year-2 (PGY-2) internal medicine residents in two affiliated hospitals. Forty-six PGY-2 residents each rotated on the Resident Inpatient Training Experience service for 1 month and completed a pre- and postrotation confidential online survey. Primary outcomes included confidence in managing hospitalized patients, knowledge regarding hospital medicine topics, and interest in pursuing hospital medicine as a career. Thirty-three PGY-2 residents completed both the pre- and postrotation survey (72% response rate). After completing the rotation, the residents' confidence level (measured on a 5-point Likert scale, with 1 = strongly disagree and 5 = strongly agree) rose significantly in managing hospitalized patients, from 3.82 to 4.33 ( P = 0.003) and in leading a ward team, from 3.76 to 4.21 ( P = 0.020). Knowledge level (measured on a 5-point Likert scale with 1 = very poor and 5 = excellent) improved significantly in transitions of care, from 3.45 to 3.79 ( P = 0.023); cost-conscious care, from 3.00 to 3.42 ( P = 0.016); physician billing/coding, from 2.55 to 3.03 ( P = 0.007); hospital metrics, from 2.39 to 2.94 ( P = 0.002); and hospital reimbursement, from 2.48 to 3.09 ( P = 0.001). Interest in pursuing hospital medicine as a career also increased. Resident independence in managing patients and training in hospital medicine topics has not kept up with evolving need. Dedicated hospital medicine rotation and curriculum are effective ways to alleviate the deficiencies in resident education.

  18. Dosimetric verification of a dedicated 3D treatment planning system for episcleral plaque therapy

    International Nuclear Information System (INIS)

    Knutsen, Stig; Hafslund, Rune; Monge, Odd R.; Valen, Harald; Muren, Ludvig Paul; Rekstad, Bernt Louni; Krohn, Joergen; Dahl, Olav

    2001-01-01

    Purpose: Episcleral plaque therapy (EPT) is applied in the management of some malignant ocular tumors. A customized configuration of typically 4 to 20 radioactive seeds is fixed in a gold plaque, and the plaque is sutured to the scleral surface corresponding to the basis of the intraocular tumor, allowing for a localized radiation dose delivery to the tumor. Minimum target doses as high as 100 Gy are directed at malignant tumor sites close to critical normal tissues (e.g., optic disc and macula). Precise dosimetry is therefore fundamental for judging both the risk for normal tissue toxicity and tumor dose prescription. This paper describes the dosimetric verification of a commercially available dedicated treatment planning system (TPS) for EPT when realistic multiple-seed configurations are applied. Materials and Methods: The TPS Bebig Plaque Simulator is used to plan EPT at our institution. Relative dose distributions in a water phantom, including central axis depth dose and off-axis dose profiles for three different plaques, the University of Southern California (USC) No. 9 and the Collaborative Ocular Melanoma Study (COMS) 12-mm and 20-mm plaques, were measured with a diode detector. Each plaque was arranged with realistic multiple 125 I seed configurations. The measured dose distributions were compared to the corresponding dose profiles calculated with the TPS. All measurements were corrected for the angular sensitivity variation of the diode. Results: Single-seed dose distributions measured with our dosimetry setup agreed with previously published data within 3%. For the three multiple-seed plaque configurations, the measured and calculated dose distributions were in good agreement. For the central axis depth doses, the agreement was within 4%, whereas deviations up to 11% were observed in single points far off-axis. Conclusions: The Bebig Plaque Simulator is a reliable TPS for calculating relative dose distributions around realistic multiple 125 I seed

  19. Cone beam computed tomography image guidance system for a dedicated intracranial radiosurgery treatment unit.

    Science.gov (United States)

    Ruschin, Mark; Komljenovic, Philip T; Ansell, Steve; Ménard, Cynthia; Bootsma, Gregory; Cho, Young-Bin; Chung, Caroline; Jaffray, David

    2013-01-01

    Image guidance has improved the precision of fractionated radiation treatment delivery on linear accelerators. Precise radiation delivery is particularly critical when high doses are delivered to complex shapes with steep dose gradients near critical structures, as is the case for intracranial radiosurgery. To reduce potential geometric uncertainties, a cone beam computed tomography (CT) image guidance system was developed in-house to generate high-resolution images of the head at the time of treatment, using a dedicated radiosurgery unit. The performance and initial clinical use of this imaging system are described. A kilovoltage cone beam CT system was integrated with a Leksell Gamma Knife Perfexion radiosurgery unit. The X-ray tube and flat-panel detector are mounted on a translational arm, which is parked above the treatment unit when not in use. Upon descent, a rotational axis provides 210° of rotation for cone beam CT scans. Mechanical integrity of the system was evaluated over a 6-month period. Subsequent clinical commissioning included end-to-end testing of targeting performance and subjective image quality performance in phantoms. The system has been used to image 2 patients, 1 of whom received single-fraction radiosurgery and 1 who received 3 fractions, using a relocatable head frame. Images of phantoms demonstrated soft tissue contrast visibility and submillimeter spatial resolution. A contrast difference of 35 HU was easily detected at a calibration dose of 1.2 cGy (center of head phantom). The shape of the mechanical flex vs scan angle was highly reproducible and exhibited cone beam CT image guidance system was successfully adapted to a radiosurgery unit. The system is capable of producing high-resolution images of bone and soft tissue. The system is in clinical use and provides excellent image guidance without invasive frames. Copyright © 2013 Elsevier Inc. All rights reserved.

  20. NiThrowTM a dedicated tool to D and D applications

    International Nuclear Information System (INIS)

    Objois, Laurent; Moggia, Fabrice; Damerval, Frederique; Varet, Thierry; Toulemonde, Valerie; Richard, Frederic

    2012-09-01

    D and D operations of nuclear site facilities, is a long, complicated and important stage. Usually, such operations involve the implementation of a large number of different technologies (mechanicals and/or chemicals) dedicated to cutting and decontamination operations. Such processes proved to work since facilities are being decommissioned. However as larger projects are foreseen, the capability of such applications to fulfil the requirement in term of economics, techniques and environment/social remains uncertain. Indeed, several aspects such as the efficiency, the speed but also the number of operators required to operate and for sure the quantity of generated wastes remain an important key point. In that context, it appears important to develop a new technology capable to be quicker, safer, and friendlier for operators and the environment. In this context, the Clean-Up Business Unit of AREVA group (BE/CL) with its partner Air Liquide worked on the development of a new cryogenic process. Started in 2008, this work was based on the use of highly pressurized liquid nitrogen in order to achieve the three mains D and D operations which are: - Cutting. - Surface decontamination. - Concrete scabbling. In this paper, three parts will be presented. The first one will give a brief overview of this new technology so called NiThrow TM . The second one will exhibit the results obtained during our different tests. And finally, the third part will be focused on the R and D developments we realized in order to fully nuclearized this NiThrow TM technology but also on its tuning in order to qualify it for nuclear environments. (authors)

  1. THE POTENTIAL FOR NEUTRINO PHYSICS AT MUON COLLIDERS AND DEDICATED HIGH CURRENT MUON STORAGE RINGS

    Energy Technology Data Exchange (ETDEWEB)

    BIGI,I.; BOLTON,T.; FORMAGGIO,J.; HARRIS,D.; MORFIN,J.; SPENTZOURIS,P.; YU,J.; KAYSER,B.; KING,B.J.; MCFARLAND,K.; PETROV,A.; SCHELLMAN,H.; VELASCO,M.; SHROCK,R.

    2000-05-11

    Conceptual design studies are underway for both muon colliders and high-current non-colliding muon storage rings that have the potential to become the first true neutrino factories. Muon decays in long straight sections of the storage rings would produce uniquely intense and precisely characterized two-component neutrino beams--muon neutrinos plus electron antineutrinos from negative muon decays and electron neutrinos plus muon antineutrinos from positive muons. This article presents a long-term overview of the prospects for these facilities to greatly extend the capabilities for accelerator-based neutrino physics studies for both high rate and long baseline neutrino experiments. As the first major physics topic, recent experimental results involving neutrino oscillations have motivated a vigorous design effort towards dedicated neutrino factories that would store muon beams of energies 50 GeV or below. These facilities hold the promise of neutrino oscillation experiments with baselines up to intercontinental distances and utilizing well understood beams that contain, for the first time, a substantial component of multi-GeV electron-flavored neutrinos. In deference to the active and fast-moving nature of neutrino oscillation studies, the discussion of long baseline physics at neutrino factories has been limited to a concise general overview of the relevant theory, detector technologies, beam properties, experimental goals and potential physics capabilities. The remainder of the article is devoted to the complementary high rate neutrino experiments that would study neutrino-nucleon and neutrino-electron scattering and would be performed at high performance detectors placed as close as is practical to the neutrino production straight section of muon storage rings in order to exploit beams with transverse dimensions as small as a few tens of centimeters.

  2. WE-FG-207A-00: Advances in Dedicated Breast CT

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2016-06-15

    Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent. Its sensitivity, especially in dense breasts, is low due to overlapping tissue and the fact that normal breast tissue, benign lesions and breast cancers all have similar “densities”, making lesion detection more difficult. We ideally need 3-D imaging for imaging the 3-D breast. MRI is 3-D, whole breast ultrasound is 3-D, digital breast tomosynthesis is called 3-D but is really “pseudo 3-D” due to poor resolution along the depth-direction. Also, and importantly, we need to be able to administer intravenous contrast agents for optimal imaging, similar to other organ systems in the body. Dedicated breast CT allows for 3-D imaging of the uncompressed breast. In current designs, the patient is positioned prone on the table and the breast is pendant through an aperture and the scan takes approximately 10 seconds [O’Connell et al., AJR 195: 496–509, 2010]. Almost on the heels of the invention of CT itself, work began on the development of dedicated breast CT. These early breast CT systems were used in clinical trials and the results from comparative performance evaluation of breast CT and mammography for 1625 subjects were reported in 1980 [Chang et al., Cancer 46: 939–46, 1980]. However, the technological limitations at that time stymied clinical translation for decades. Subsequent to the landmark article in 2001 [Boone et al., Radiology 221: 657–67, 2001] that demonstrated the potential feasibility in terms of radiation dose, multiple research groups are actively

  3. Evaluation of a dedicated MDCT protocol using iterative image reconstruction after cervical spine trauma

    International Nuclear Information System (INIS)

    Geyer, L.L.; Körner, M.; Hempel, R.; Deak, Z.; Mueck, F.G.; Linsenmaier, U.; Reiser, M.F.; Wirth, S.

    2013-01-01

    Aim: To evaluate radiation exposure for 64-row computed tomography (CT) of the cervical spine comparing two optimized protocols using filtered back projection (FBP) and adaptive statistical iterative reconstruction (ASIR), respectively. Materials and methods: Sixty-seven studies using FBP (scanner 1) were retrospectively compared with 80 studies using ASIR (scanner 2). The key scanning parameters were identical (120 kV dose modulation, 64 × 0.625 mm collimation, pitch 0.531:1). In protocol 2, the noise index (NI) was increased from 5 to 25, and ASIR and the high-definition (HD) mode were used. The scan length, CT dose index (CTDI), and dose–length product (DLP) were recorded. The image quality was analysed subjectively by using a three-point scale (0; 1; 2), and objectively by using a region of interest (ROI) analysis. Mann–Whitney U and Wilcoxon's test were used. Results: In the FBP group, the mean CTDI was 21.43 mGy, mean scan length 186.3 mm, and mean DLP 441.15 mGy cm. In the ASIR group, the mean CTDI was 9.57 mGy, mean scan length 195.21 mm, and mean DLP 204.23 mGy cm. The differences were significant for CTDI and DLP (p 0.05). The estimated mean effective dose decreased from 2.38 mSv (FBP) to 1.10 mSv (ASIR). Conclusion: The radiation dose of 64-row MDCT can be reduced to a level comparable to plain radiography without loss of subjective image quality by implementation of ASIR in a dedicated cervical spine trauma protocol. These results might contribute to an improved relative risk-to-benefit ratio and support the justification of CT as a first-line imaging tool to evaluate cervical spine trauma

  4. Study and development of a PET device dedicated to cancer monitoring

    International Nuclear Information System (INIS)

    Vandenbussche, Vincent

    2014-01-01

    Medical imaging first began at the end of the 19. century with the discover of X-rays by Roentgen. Then, numerous imaging modalities have been developed and are used now for a wide range of cases. Positron Emission Tomography (PET) has a high sensitivity, is functional and quantitative, thus being of high interest in cancer monitoring. Nevertheless, PET is not as much spread in hospitals as magnetic resonance imaging and scanner. In this context, this work aims to prove the feasibility of PET dedicated for cancer monitoring. Thanks to instrumental developments such as light sharing in scintillating crystals, use of Silicon Photomultipliers, and an original geometry, cost is expected to be reduced while having same performances as commercial devices. An extensive study of light sharing within scintillating barrels has been made, through many parameters (crystal length, coating, data analysis...). An intrinsic spatial resolution of 4 mm has been measured over a 75 mm long crystal of LYSO, coated with teflon. From such a configuration, a first image has been reconstructed using two modules in coincidence. A spatial resolution of 5 mm has been measured in the image. Finally, Monte Carlo simulations has been made with experimental data as input, in order to measure the performances of the final PET device. Thanks to NEMA standard protocol, performances has been measured and compared to other systems. A spatial resolution of 4 mm has been reached, for a sensitivity of 2.5 cps/kBq. Quantification problem has been assessed, providing results similar to existing devices. (author) [fr

  5. WE-FG-207A-01: Introduction to Dedicated Breast CT - Early Studies

    Energy Technology Data Exchange (ETDEWEB)

    Vedantham, S. [University of Massachusetts Medical School (United States)

    2016-06-15

    Mammography-based screening has been a valuable imaging tool for the early detection of non-palpable lesions and has contributed to significant reduction in breast cancer associated mortality. However, the breast imaging community recognizes that mammography is not ideal, and in particular is inferior for women with dense breasts. Also, the 2-D projection of a 3-D organ results in tissue superposition contributing to false-positives. The sensitivity of mammography is breast-density dependent. Its sensitivity, especially in dense breasts, is low due to overlapping tissue and the fact that normal breast tissue, benign lesions and breast cancers all have similar “densities”, making lesion detection more difficult. We ideally need 3-D imaging for imaging the 3-D breast. MRI is 3-D, whole breast ultrasound is 3-D, digital breast tomosynthesis is called 3-D but is really “pseudo 3-D” due to poor resolution along the depth-direction. Also, and importantly, we need to be able to administer intravenous contrast agents for optimal imaging, similar to other organ systems in the body. Dedicated breast CT allows for 3-D imaging of the uncompressed breast. In current designs, the patient is positioned prone on the table and the breast is pendant through an aperture and the scan takes approximately 10 seconds [O’Connell et al., AJR 195: 496–509, 2010]. Almost on the heels of the invention of CT itself, work began on the development of dedicated breast CT. These early breast CT systems were used in clinical trials and the results from comparative performance evaluation of breast CT and mammography for 1625 subjects were reported in 1980 [Chang et al., Cancer 46: 939–46, 1980]. However, the technological limitations at that time stymied clinical translation for decades. Subsequent to the landmark article in 2001 [Boone et al., Radiology 221: 657–67, 2001] that demonstrated the potential feasibility in terms of radiation dose, multiple research groups are actively

  6. Optimization of a dedicated bio-imaging beamline at the European X-ray FEL

    International Nuclear Information System (INIS)

    Geloni, Gianluca; Kocharyan, Vitali; Saldin, Evgeni

    2012-09-01

    We recently proposed a basic concept for design and layout of the undulator source for a dedicated bio-imaging beamline at the European XFEL. The goal of the optimized scheme proposed here is to enable experimental simplification and performance improvement. The core of the scheme is composed by soft and hard X-ray self-seeding setups. Based on the use of an improved design for both monochromators it is possible to increase the design electron energy up to 17.5 GeV in photon energy range between 2 keV and 13 keV, which is the most preferable for life science experiments. An advantage of operating at such high electron energy is the increase of the X-ray output peak power. Another advantage is that 17.5 GeV is the preferred operation energy for SASE1 and SASE2 beamline users. Since it will be necessary to run all the XFEL lines at the same electron energy, this choice will reduce the interference with other undulator lines and increase the total amount of scheduled beam time. In this work we also propose a study of the performance of the self-seeding scheme accounting for spatiotemporal coupling caused by the use of a single crystal monochromator. Our analysis indicates that this distortion is easily suppressed by the right choice of diamond crystal planes and that the proposed undulator source yields about the same performance as in the case for a X-ray seed pulse with no coupling. Simulations show that the FEL power reaches 2 TW in the 3 keV-5 keV photon energy range, which is the most preferable for single biomolecule imaging.

  7. WE-DE-207B-12: Scatter Correction for Dedicated Cone Beam Breast CT Based On a Forward Projection Model

    Energy Technology Data Exchange (ETDEWEB)

    Shi, L; Zhu, L [Georgia Institute of Technology, Atlanta, GA (Georgia); Vedantham, S; Karellas, A [University of Massachusetts Medical School, Worcester, MA (United States)

    2016-06-15

    Purpose: The image quality of dedicated cone-beam breast CT (CBBCT) is fundamentally limited by substantial x-ray scatter contamination, resulting in cupping artifacts and contrast-loss in reconstructed images. Such effects obscure the visibility of soft-tissue lesions and calcifications, which hinders breast cancer detection and diagnosis. In this work, we propose to suppress x-ray scatter in CBBCT images using a deterministic forward projection model. Method: We first use the 1st-pass FDK-reconstructed CBBCT images to segment fibroglandular and adipose tissue. Attenuation coefficients are assigned to the two tissues based on the x-ray spectrum used for imaging acquisition, and is forward projected to simulate scatter-free primary projections. We estimate the scatter by subtracting the simulated primary projection from the measured projection, and then the resultant scatter map is further refined by a Fourier-domain fitting algorithm after discarding untrusted scatter information. The final scatter estimate is subtracted from the measured projection for effective scatter correction. In our implementation, the proposed scatter correction takes 0.5 seconds for each projection. The method was evaluated using the overall image spatial non-uniformity (SNU) metric and the contrast-to-noise ratio (CNR) with 5 clinical datasets of BI-RADS 4/5 subjects. Results: For the 5 clinical datasets, our method reduced the SNU from 7.79% to 1.68% in coronal view and from 6.71% to 3.20% in sagittal view. The average CNR is improved by a factor of 1.38 in coronal view and 1.26 in sagittal view. Conclusion: The proposed scatter correction approach requires no additional scans or prior images and uses a deterministic model for efficient calculation. Evaluation with clinical datasets demonstrates the feasibility and stability of the method. These features are attractive for clinical CBBCT and make our method distinct from other approaches. Supported partly by NIH R21EB019597, R21CA134128

  8. Inform@ed space

    DEFF Research Database (Denmark)

    Bjerrum, Peter; Olsen, Kasper Nefer

    2001-01-01

    Inform@ed space Sensorial Perception And Computer Enchancement - bidrag til Nordisk Arkitekturforskningsforenings IT-konference, AAA april 2001.......Inform@ed space Sensorial Perception And Computer Enchancement - bidrag til Nordisk Arkitekturforskningsforenings IT-konference, AAA april 2001....

  9. Design and development of a high resolution animal SPECT scanner dedicated for rat and mouse imaging

    International Nuclear Information System (INIS)

    Sajedi, Salar; Zeraatkar, Navid; Moji, Vahideh; Farahani, Mohammad Hossein; Sarkar, Saeed; Arabi, Hossein; Teymoorian, Behnoosh; Ghafarian, Pardis; Rahmim, Arman; Reza Ay, Mohammad

    2014-01-01

    A dedicated small-animal SPECT system, HiReSPECT, was designed and developed to provide a high resolution molecular imaging modality in response to growing research demands. HiReSPECT is a dual-head system mounted on a rotating gantry. The detection system is based on pixelated CsI(Na) scintillator crystals coupled to two Hamamatsu H8500 Position Sensitive Photomultiplier Tubes in each head. Also, a high resolution parallel-hole collimator is applied to every head. The dimensions of each head are 50 mm×100 mm, enabling sufficient transaxial and axial fields-of-view (TFOV and AFOV), respectively, for coverage of the entire mouse in single-bed position imaging. However, a 50 mm TFOV is not sufficient for transaxial coverage of rats. To address this, each head can be rotated by 90 degrees in order to align the larger dimension of the heads with the short body axis, allowing tomographic data acquisition for rats. An innovative non-linear recursive filter was used for signal processing/detection. Resolution recovery was also embedded in the modified Maximum-Likelihood Expectation Maximization (MLEM) image reconstruction code to compensate for Collimator-Detector Response (CDR). Moreover, an innovative interpolation algorithm was developed to speed up the reconstruction code. The planar spatial resolution at the head surface and the image spatial resolutions were 1.7 mm and 1.2–1.6 mm, respectively. The measurements followed by post-processing showed that the observed count rate at 20% count loss is about 42 kcps. The system sensitivity at the collimator surface for heads 1 and 2 were 1.32 cps/µCi and 1.25 cps/µCi, respectively. The corresponding values were 1.18 cps/µCi and 1.02 cps/µCi at 8 cm distance from the collimator surfaces. In addition, whole-body scans of mice demonstrated appropriate imaging capability of the HiReSPECT

  10. Benchmarking of Typical Meteorological Year datasets dedicated to Concentrated-PV systems

    Science.gov (United States)

    Realpe, Ana Maria; Vernay, Christophe; Pitaval, Sébastien; Blanc, Philippe; Wald, Lucien; Lenoir, Camille

    2016-04-01

    suitable for CPV systems. For these systems, the TMY datasets obtained using dedicated drivers (DNI only or more precise one) are more representative to derive TMY datasets from limited long-term meteorological dataset.

  11. Library based x-ray scatter correction for dedicated cone beam breast CT

    International Nuclear Information System (INIS)

    Shi, Linxi; Zhu, Lei; Vedantham, Srinivasan; Karellas, Andrew

    2016-01-01

    Purpose: The image quality of dedicated cone beam breast CT (CBBCT) is limited by substantial scatter contamination, resulting in cupping artifacts and contrast-loss in reconstructed images. Such effects obscure the visibility of soft-tissue lesions and calcifications, which hinders breast cancer detection and diagnosis. In this work, we propose a library-based software approach to suppress scatter on CBBCT images with high efficiency, accuracy, and reliability. Methods: The authors precompute a scatter library on simplified breast models with different sizes using the GEANT4-based Monte Carlo (MC) toolkit. The breast is approximated as a semiellipsoid with homogeneous glandular/adipose tissue mixture. For scatter correction on real clinical data, the authors estimate the breast size from a first-pass breast CT reconstruction and then select the corresponding scatter distribution from the library. The selected scatter distribution from simplified breast models is spatially translated to match the projection data from the clinical scan and is subtracted from the measured projection for effective scatter correction. The method performance was evaluated using 15 sets of patient data, with a wide range of breast sizes representing about 95% of general population. Spatial nonuniformity (SNU) and contrast to signal deviation ratio (CDR) were used as metrics for evaluation. Results: Since the time-consuming MC simulation for library generation is precomputed, the authors’ method efficiently corrects for scatter with minimal processing time. Furthermore, the authors find that a scatter library on a simple breast model with only one input parameter, i.e., the breast diameter, sufficiently guarantees improvements in SNU and CDR. For the 15 clinical datasets, the authors’ method reduces the average SNU from 7.14% to 2.47% in coronal views and from 10.14% to 3.02% in sagittal views. On average, the CDR is improved by a factor of 1.49 in coronal views and 2.12 in sagittal

  12. Library based x-ray scatter correction for dedicated cone beam breast CT

    Energy Technology Data Exchange (ETDEWEB)

    Shi, Linxi; Zhu, Lei, E-mail: leizhu@gatech.edu [Nuclear and Radiological Engineering and Medical Physics Programs, The George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332 (United States); Vedantham, Srinivasan; Karellas, Andrew [Department of Radiology, University of Massachusetts Medical School, Worcester, Massachusetts 01655 (United States)

    2016-08-15

    Purpose: The image quality of dedicated cone beam breast CT (CBBCT) is limited by substantial scatter contamination, resulting in cupping artifacts and contrast-loss in reconstructed images. Such effects obscure the visibility of soft-tissue lesions and calcifications, which hinders breast cancer detection and diagnosis. In this work, we propose a library-based software approach to suppress scatter on CBBCT images with high efficiency, accuracy, and reliability. Methods: The authors precompute a scatter library on simplified breast models with different sizes using the GEANT4-based Monte Carlo (MC) toolkit. The breast is approximated as a semiellipsoid with homogeneous glandular/adipose tissue mixture. For scatter correction on real clinical data, the authors estimate the breast size from a first-pass breast CT reconstruction and then select the corresponding scatter distribution from the library. The selected scatter distribution from simplified breast models is spatially translated to match the projection data from the clinical scan and is subtracted from the measured projection for effective scatter correction. The method performance was evaluated using 15 sets of patient data, with a wide range of breast sizes representing about 95% of general population. Spatial nonuniformity (SNU) and contrast to signal deviation ratio (CDR) were used as metrics for evaluation. Results: Since the time-consuming MC simulation for library generation is precomputed, the authors’ method efficiently corrects for scatter with minimal processing time. Furthermore, the authors find that a scatter library on a simple breast model with only one input parameter, i.e., the breast diameter, sufficiently guarantees improvements in SNU and CDR. For the 15 clinical datasets, the authors’ method reduces the average SNU from 7.14% to 2.47% in coronal views and from 10.14% to 3.02% in sagittal views. On average, the CDR is improved by a factor of 1.49 in coronal views and 2.12 in sagittal

  13. Dedicated new descaling method to characterize corrosion and cation release of SG tubing materials

    International Nuclear Information System (INIS)

    Clauzel, Maryline; Guillodo, Michael; Foucault, Marc; Engler, Nathalie; Chahma, Farah

    2012-09-01

    optimization is the fact that the primary fluid is circulating in the autoclave and not 'static' and the fluid flowing out the autoclave is not reinjected in the autoclave, limiting the risks of saturation of the fluid by CP. Some tests with the optimized descaling technique have been performed by coupling the autoclave to the PETER micro-loop dedicated to online cation release kinetics measurements in order to compare the results of both techniques. Promising results have been obtained and both techniques showed the same tendencies for the tube. (authors)

  14. The FREGAT biobank: a clinico-biological database dedicated to esophageal and gastric cancers.

    Science.gov (United States)

    Mariette, Christophe; Renaud, Florence; Piessen, Guillaume; Gele, Patrick; Copin, Marie-Christine; Leteurtre, Emmanuelle; Delaeter, Christine; Dib, Malek; Clisant, Stéphanie; Harter, Valentin; Bonnetain, Franck; Duhamel, Alain; Christophe, Véronique; Adenis, Antoine

    2018-02-06

    patient survival. This database was initially developed in France on a nationwide basis, but currently, the database is available for worldwide contributions with respect to the input of patient data or the request for data for scientific projects. The FREGAT database has a dedicated website ( www.fregat-database.org ) and is registered on the Clinicaltrials.gov site, number NCT 02526095 , since August 8, 2015.

  15. [Email in a dedicated headache clinic: experience gained over a five-year period].

    Science.gov (United States)

    Pedraza, M Isabel; Herrero-Velázquez, Sonia; López-Mesonero, Luis; Ruiz-Piñero, Marina; Posadas, Javier; Guerrero-Peral, Ángel L

    2015-06-16

    The use of email can facilitate communication between the different levels of an organisation. Our primary care physicians have had an email service in the dedicated headache clinic (DHC) since November 2009, and our aim is therefore to analyse the use of email over that five-year period. Data concerning the emails sent up until October 2014 were collected prospectively. The questions were classified as need for referral to the DHC (group 1), progress made by the cases seen in the DHC (group 2), training in headaches (group 3) or the treatment of the headaches suffered by primary care physicians themselves as patients (group 4). A total of 274 email messages were analysed. Monthly consultations have increased (from 1.5 per month during the first year to 7.5 per month during the fifth). Findings showed that 10.2% of the email messages came from rural health centres and 89.8% were sent from urban health centres. Replies were sent within 2 ± 2.8 days (range: 0-24 days). Altogether 130 consultations were classified as belonging to group 1 (47.4%), in which referral through the normal channel was recommended in 60 cases (46.2%), via the preferential channel in 47 (36.2%) and non-referral was suggested in 23 cases (17.6%). Group 2 included 125 emails (45.7%) and in 80 cases there was no need to make a new appointment or to bring forward the existing one (64%). Thirteen visits (4.7%) were classified into group 3 and six (2.2%) in group 4. Our primary care physicians are using the email of the DHC on an increasingly more frequent basis. Its use makes it possible to detect patients whose appointment -whether the first or a follow-up- needs to be brought forward, as well as allowing issues to be solved without the need for referral. It is effective for the treatment of physicians who themselves have headaches and as a tool for continuing education.

  16. Information Management for Factory Planning and Design

    OpenAIRE

    Chen, Danfang

    2012-01-01

    This thesis is dedicated to the manufacturing industry for the improvement of information management within the factory planningand design domain, and for more efficient factory planning and design. Currently the manufacturing industry lacks sufficient methods for capturing, structuring, and representing information and knowledge for easy access, exchange, integration and reuse within the domain. Therefore the focus of this thesis is on information and knowledge management within factory plan...

  17. Factors affecting physicians’ use of a dedicated overview interface in an electronic health record

    DEFF Research Database (Denmark)

    Jensen, Lotte Groth; Bossen, Claus

    2016-01-01

    Background : It remains a continual challenge to present information in user interfaces in large IT systems to support overview in the best possible way. We here examine how an Electronic Health Record (EHR) supports the creation of overview among hospital physicians with a particular focus...... the reasons for its use and non-use Method: We conducted exploratory ethnographic fieldwork among physicians in two hospitals and gathered statistical data on their use of the overview interface. From the quantitative data, we identified where the interface was used most and conducted 18 semi-structured, open-ended...... on the use of an interface designed to provide clinicians with a patient information overview. The overview interface integrates information flexibly from diverse places in the EHR and presents this information in one screen display. Our study revealed widespread non-use of the overview interface. We explore...

  18. A study on the establishment of safety assessment guidelines of commercial grade item dedication in digitalized safety systems

    International Nuclear Information System (INIS)

    Hwang, H. S.; Kim, B. R.; Oh, S. H.

    1999-01-01

    Because of obsolescing the components used in safety related systems of nuclear power plants, decreasing the number of suppliers qualified for the nuclear QA program and increasing maintenance costs of them, utilities have been considering to use commercial grade digital computers as an alternative for resolving such issues. However, commercial digital computers use the embedded pre-existing software, including operating system software, which are not developed by using nuclear grade QA program. Thus, it is necessary for utilities to establish processes for dedicating digital commercial grade items. A regulatory body also needs guidance to evaluate the digital commercial products properly. This paper surveyed the regulations and their regulatory guides, which establish the requirements for commercial grade items dedication, industry standards and guidances applicable to safety related systems. This paper provides some guidelines to be applied in evaluating the safety of digital upgrades and new digital plant protection systems in Korea

  19. Towards a Tissue-Engineered Ligament: Design and Preliminary Evaluation of a Dedicated Multi-Chamber Tension-Torsion Bioreactor

    Directory of Open Access Journals (Sweden)

    Cédric P. Laurent

    2014-02-01

    Full Text Available Tissue engineering may constitute a promising alternative to current strategies in ligament repair, providing that suitable scaffolds and culture conditions are proposed. The objective of the present contribution is to present the design and instrumentation of a novel multi-chamber tension-torsion bioreactor dedicated to ligament tissue engineering. A preliminary biological evaluation of a new braided scaffold within this bioreactor under dynamic loading is reported, starting with the development of a dedicated seeding protocol validated from static cultures. The results of these preliminary biological characterizations confirm that the present combination of scaffold, seeding protocol and bioreactor may enable us to head towards a suitable ligament tissue-engineered construct.

  20. Student and Preceptor Advancement in a Dedicated Education Site: Innovation in Clinical Education for Advanced Practice Nurses.

    Science.gov (United States)

    Hall, Katherine C; Diffenderfer, Sandy K; Stidham, April; Mullins, Christine M

    2018-04-19

    In the 1990s, dedicated education units transformed undergraduate preceptorships, but graduate preceptorships remain static. The dyadic nurse practitioner preceptorship model supports an environment where faculty, students, and preceptors may overlook nuances that affect the teaching-learning process. This article describes an innovative clinical education model, Student and Preceptor Advancement in a Dedicated Education Site, designed to improve preceptorships for advanced practice nurses. The focus is on adaptations made to facilitate use in advanced practice nursing programs.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

  1. A development of an accelerator board dedicated for multi-precision arithmetic operations and its application to Feynman loop integrals

    International Nuclear Information System (INIS)

    Motoki, S; Ishikawa, T; Yuasa, F; Daisaka, H; Nakasato, N; Fukushige, T; Kawai, A; Makino, J

    2015-01-01

    Higher order corrections in perturbative quantum field theory are required for precise theoretical analysis to investigate new physics beyond the Standard Model. This indicates that we need to evaluate Feynman loop diagrams with multi-loop integrals which may require multi-precision calculation. We developed a dedicated accelerator system for multiprecision calculations (GRAPE9-MPX). We present performance results of our system for the case of Feynman two-loop box and three-loop selfenergy diagrams with multi-precision. (paper)

  2. Constraints and Dedication as Drivers for Relationship Commitment: An Empirical Study in a Health-Care Context

    OpenAIRE

    Gaby Odekerken-Schröder; Bloemer Josée

    2002-01-01

    The objective of this study is to empirically determine the role of constraints and dedication as drivers of relationship commitment as most of the existing work is of a conceptual nature only. We assess how and to which extent these two drivers fit into the established relationships between overall service quality, satisfaction, trust and commitment. Using LISREL, we estimate the conceptual model based on a sample of customers of health-care centers. The results indicate that both constraint...

  3. COG: information exchange. The new initiatives

    International Nuclear Information System (INIS)

    Guiry, C.

    2000-01-01

    The CANDU Owners Group (COG) is dedicated to providing programs for cooperation, mutual assistance and exchange of information for the successful support, development, operation, maintenance and economics of CANDU Technology. This paper summarises the COG Mission, COG Vision and COG Values

  4. Initial clinical experience with dedicated ultra fast solid state cardiac gamma camera

    International Nuclear Information System (INIS)

    Aland, Nusrat; Lele, V.

    2010-01-01

    Full text: To analyze the imaging and diagnostic performance of new dedicated ultra fast solid state detector gamma camera and compare it with standard dual detector gamma camera in myocardial perfusion imaging. Material and Methods: In total 900 patients underwent myocardial perfusion imaging between 1st February 2010 and 29th August 2010 either stress/rest or rest/stress protocol. There was no age or gender bias (there were 630 males and 270 females). 5 and 15 mCi of 99m Tc - Tetrofosmin/MIBI was injected for 1st and 2nd part of the study respectively. Waiting period after injection was 20 min for regular stress and 40 min for pharmacological stress and 40 min after rest injection. Acquisition was performed on solid state detector gamma camera for a duration of 5 min and 3 min for 1st and 2nd part respectively. Interpretation of myocardial perfusion was done and QGS/QPS protocol was used for EF analysis. Out of these, 20 random patients underwent back to back myocardial perfusion SPECT imaging on standard dual detector gamma camera on same day. There was no age or gender bias (there were 9 males, 11 females). Acquisition time was 20 min for each part of the study. Interpretation was done using Autocard and EF analyses with 4 DM SPECT. Images obtained were then compared with those of solid state detector gamma camera. Result: Good quality and high count myocardial perfusion images were obtained with lesser amount of tracer activity on solid state detector gamma camera. Obese patients also showed good quality images with less tracer activity. As compared to conventional dual detector gamma camera images were brighter and showed better contrast with solid state gamma camera. Right ventricular imaging was better seen. Analyses of diastolic dysfunction was possible with 16 frame gated studies with solid state gamma camera. Shorter acquisition time with comfortable position reduced possibility of patient motion. All cardiac views were obtained with no movement of the

  5. Conference '48-annual Science-Practical Conference of Medical University, dedicated to tenth anniversary of Independence of the Republic of Tajikistan'. Proceedings

    International Nuclear Information System (INIS)

    2001-01-01

    In this collection bring together scientific articles, which was presented on 48-annual Science-Practical Conference of Medical University, dedicated to tenth anniversary of Independence of the Republic of Tajikistan. Those articles dedicated to different directions of medicine and progress of Tajik State Medical University in medical science

  6. Development of a circular shape Si-PM-based detector ring for breast-dedicated PET system

    Science.gov (United States)

    Nakanishi, Kouhei; Yamamoto, Seiichi; Watabe, Hiroshi; Abe, Shinji; Fujita, Naotoshi; Kato, Katsuhiko

    2018-02-01

    In clinical situations, various breast-dedicated positron emission tomography (PET) systems have been used. However, clinical breast-dedicated PET systems have polygonal detector ring. Polygonal detector ring sometimes causes image artifact, so complicated reconstruction algorithm is needed to reduce artifact. Consequently, we developed a circular detector ring for breast-dedicated PET to obtain images without artifact using a simple reconstruction algorithm. We used Lu1.9Gd0.1SiO5 (LGSO) scintillator block which was made of 1.5 x 1.9 x 15 mm pixels that were arranged in an 8 x 24 matrix. As photodetectors, we used silicon photomultiplier (Si-PM) arrays whose channel size was 3 x 3 mm. A detector unit was composed of four scintillator blocks, 16 Si-PM arrays and a light guide. The developed detector unit had angled configuration since the light guide was bending. A detector unit had three gaps with an angle of 5.625° between scintillator blocks. With these configurations, we could arrange 64 scintillator blocks in nearly circular shape (regular 64-sided polygon) using 16 detector units. The use of the smaller number of detector units could reduce the size of the front-end electronics circuits. The inner diameter of the developed detector ring was 260 mm. This size was similar to those of brain PET systems, so our breast-dedicated PET detector ring can measure not only breast but also brain. Measured radial, tangential and axial spatial resolution of the detector ring reconstructed by the filtered back-projection (FBP) algorithm were 2.1 mm FWHM, 2.0 mm FWHM and 1.7 mm FWHM at center of field of view (FOV), respectively. The sensitivity was 2.0% at center of the axial FOV. With the developed detector ring, we could obtain high resolution image of the breast phantom and the brain phantom. We conclude that our developed Si-PM-based detector ring is promising for a high resolution breast-dedicated PET system that can also be used for brain PET system.

  7. Dedicated clock/timing-circuit theories of time perception and timed performance

    NARCIS (Netherlands)

    van Rijn, Hedderik; Gu, Bon-Mi; Meck, Warren H

    2014-01-01

    Scalar Timing Theory (an information-processing version of Scalar Expectancy Theory) and its evolution into the neurobiologically plausible Striatal Beat-Frequency (SBF) theory of interval timing are reviewed. These pacemaker/accumulator or oscillation/coincidence detection models are then

  8. “CONTINENTAL RIFTING, ACCOMPANYING PROCESSES” SYMPOSIUM DEDICATED TO THE MEMORY OF N.A. LOGACHEV AND E.E. MILANOVSKY, ‘ACADEMICIANS OF RIFTING’, 20–23 AUGUST 2013, IRKUTSK, RUSSIA

    Directory of Open Access Journals (Sweden)

    S. V. Rasskazov

    2013-01-01

    Full Text Available  The article provides information about “Continental rifting, accompanying processes” Symposium dedicated to the memory of N.A. Logachev and E.E. Milanovsky, ‘Academicians of Rifting’. The symposium took place on 20–23 August 2013. It was initiated and arranged by the Institute of the Earth's Crust SB RAS and the Geological Faculty of the Irkutsk State University (Irkutsk with participation of the Geological Faculty of Moscow State University. Topics of the symposium are reviewed.  

  9. From surfaces to magnetic properties: special section dedicated to Juan Rojo

    Science.gov (United States)

    Mascaraque, A.; Rodríguez de la Fuente, O.; González-Barrio, Miguel A.

    2013-12-01

    by Barandiarán et al. In the following paper, Crespo et al review the effect of organic and inorganic coatings on magnetic nanoparticles, showing that the coating can tune the magnetic properties of metallic and oxide nano-sized particles. Barja et al report on ordered magnetic ion structures formed by evaporation of Mn and Fe on self-assembled layers of tetracyanoquinodimethane (TCNQ) molecules on Cu(111). Finally, Rodríguez de la Fuente et al investigate the role of surface defects on the physico-chemical properties of metals and oxides in a variety of scenarios, showing how the surface controls the mechanical properties probed at the nanoscale or the chemical reactivity. Acknowledgments The editors are grateful to all the invited contributors to this special section of Journal of Physics: Condensed Matter . We also thank the staff of IOP Publishing for handling the administrative matters and the refereeing process, and for their patience and helpful disposition. From surfaces to magnetic properties contents From surfaces to magnetic properties: special section dedicated to Juan RojoA Mascaraque, O Rodríguez de la Fuente and Miguel A González-Barrio Juan Rojo: the surface science and science politics maker in SpainA Mascaraque, O Rodríguez de la Fuente, Miguel A González-Barrio, Javier Solana, Luis Oro and Ana Crespo Initial stages of FeO growth on Ru(0001)I Palacio, M Monti, J F Marco, K F McCarty and J de la Figuera Surprising resistivity decrease in manganites with constant electronic densityR Cortés-Gil, M L Ruiz-González, J M Alonso, J L Martínez, A Hernando, M Vallet-Regí, and J M González-Calbet Thermoseeds for interstitial magnetic hyperthermia: from bioceramics to nanoparticlesA Baeza, D Arcos and M Vallet-Regí Revisited magnetic phase diagram for CeNi1-xCux system: spin-glass in the weak interaction limitN Marcano, J I Espeso and J C Gómez Sal Magnetic field and atomic order effect on the martensitic transformation of a metamagnetic alloyJ M

  10. Lessons learnt from Volcanoes' Night I-II-III - a Marie Curie Researchers' Night project series dedicated to geosciences

    Science.gov (United States)

    Cseko, Adrienn; Bodo, Balazs; Ortega Rodriguez, Ariadna

    2017-04-01

    European Researchers' Nights (ERNs) are a pan-European series of events funded by the European Commission, organised on the last Friday of every September since 2005. ERNs mobilise scientific, academic and research organisations with the aim of giving the public the opportunity to meet researchers in an informal setting. The overall objective of ERNs is to achieve better awareness among the general public concerning the importance of science in everyday life and to combat stereotypes about researchers. The longer-term strategic objective of ERNs is to encourage young people to embark on a scientific career. Volcanoes' Night I-II-III has been an ERN project series funded by the EC FP7 and H2020 programmes between 2012-2015 (EC contract No. 316558, 610050, 633310, www.nochedevolcanes.es). The concept of Volcanoes' Night was created by researchers from the Canary Islands, Spain, where both the researchers and the public live in the close vicinity of volcanoes. The objective of the project was to use volcanoes as a background against which the role of geoscientists could be explained to the public. The scope of Volcanoes' Night was exclusively dedicated to geoscience, and in this respect it stands out among all other ERN projects, which are always more general in scope. During its four years of EC funding, the geographical coverage of Volcanoes' Night expanded substantially from a single location in 2012 (Fuencaliente de La Palma, Spain) to a dozen locations in 2015, mobilising multiple scientific organisations, researchers, and public authorities for engagement with the public. The last EC-funded project, Volcanoes' Night III, which was organised in 2014 and 2015, engaged approximately 21,000 visitors through its outreach activities, which included experiments, science cafés, volcano movies, My Day presentations, excursions, science workshops and more. The impact of the project was carefully assessed via surveys and social studies during its lifetime, and an Impact

  11. Principles and core functions of integrated child health information systems.

    Science.gov (United States)

    Hinman, Alan R; Atkinson, Delton; Diehn, Tonya Norvell; Eichwald, John; Heberer, Jennifer; Hoyle, Therese; King, Pam; Kossack, Robert E; Williams, Donna C; Zimmerman, Amy

    2004-11-01

    Infants undergo a series of preventive and therapeutic health interventions and activities. Typically, each activity includes collection and submission of data to a dedicated information system. Subsequently, health care providers, families, and health programs must query each information system to determine the child's status in a given area. Efforts are underway to integrate information in these separate information systems. This requires specifying the core functions that integrated information systems must perform.

  12. SUPPORTING INFORMATION

    Indian Academy of Sciences (India)

    Mitradip

    ... THEORETICAL CHEMISTRY/CHEMICAL DYNAMICS. REGULAR ARTICLE. A Computational Investigation of the Red and Blue Shifts in Hydrogen Bonded Systems ... 400 098, India. *Email: swapankghosh@gmail.com. *For Correspondence. Footnote:Dedicated to the memory of the late Professor Charusita Chakravarty ...

  13. Experience on the COTS Software Dedication of the PROFIBUS FMS-Driver

    International Nuclear Information System (INIS)

    Kim, Jang Yeol; Lee, Young Jun; Cha, Kyung Ho; Cheon, Se Woo; Lee, Jang Soo; Kwon, Kee Choon

    2007-01-01

    From the middle of the 1980's, the field bus has been developed for the network system which supports the real-time communication of various controls and automation equipment. It is known for PROFIBUS in the field of a production automation environment. The PROFIBUS architecture uses open communication (ISO 7498) based on the ISO/OSI model. The PROFIBUS standard uses layer 1 (physical layer : PHY), layer 2, (data link : FDL) and layer 7 (application). Layer 7 of PROFIBUS FMS(Fieldbus Message Specification) provides a information level communication service to a communication and the user of a station

  14. Experience on the COTS Software Dedication of the PROFIBUS FMS-Driver

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jang Yeol; Lee, Young Jun; Cha, Kyung Ho; Cheon, Se Woo; Lee, Jang Soo; Kwon, Kee Choon [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2007-07-01

    From the middle of the 1980's, the field bus has been developed for the network system which supports the real-time communication of various controls and automation equipment. It is known for PROFIBUS in the field of a production automation environment. The PROFIBUS architecture uses open communication (ISO 7498) based on the ISO/OSI model. The PROFIBUS standard uses layer 1 (physical layer : PHY), layer 2, (data link : FDL) and layer 7 (application). Layer 7 of PROFIBUS FMS(Fieldbus Message Specification) provides a information level communication service to a communication and the user of a station.

  15. Validation of the U-238 inelastic scattering neutron cross section through the EXCALIBUR dedicated experiment

    OpenAIRE

    Leconte Pierre; Bernard David

    2017-01-01

    EXCALIBUR is an integral transmission experiment based on the fast neutron source produced by the bare highly enriched fast burst reactor CALIBAN, located in CEA/DAM Valduc (France). Two experimental campaigns have been performed, one using a sphere of diameter 17 cm and one using two cylinders of 17 cm diameter 9 cm height, both made of metallic Uranium 238. A set of 15 different dosimeters with specific threshold energies have been employed to provide information on the neutron flux attenua...

  16. LauncherOne: Virgin Orbit's Dedicated Launch Vehicle for Small Satellites & Impact to the Space Enterprise Vision

    Science.gov (United States)

    Vaughn, M.; Kwong, J.; Pomerantz, W.

    Virgin Orbit is developing a space transportation service to provide an affordable, reliable, and responsive dedicated ride to orbit for smaller payloads. No longer will small satellite users be forced to make a choice between accepting the limitations of flight as a secondary payload, paying dramatically more for a dedicated launch vehicle, or dealing with the added complexity associated with export control requirements and international travel to distant launch sites. Virgin Orbit has made significant progress towards first flight of a new vehicle that will give satellite developers and operators a better option for carrying their small satellites into orbit. This new service is called LauncherOne (See the figure below). LauncherOne is a two stage, air-launched liquid propulsion (LOX/RP) rocket. Air launched from a specially modified 747-400 carrier aircraft (named “Cosmic Girl”), this system is designed to conduct operations from a variety of locations, allowing customers to select various launch azimuths and increasing available orbital launch windows. This provides small satellite customers an affordable, flexible and dedicated option for access to space. In addition to developing the LauncherOne vehicle, Virgin Orbit has worked with US government customers and across the new, emerging commercial sector to refine concepts for resiliency, constellation replenishment and responsive launch elements that can be key enables for the Space Enterprise Vision (SEV). This element of customer interaction is being led by their new subsidiary company, VOX Space. This paper summarizes technical progress made on LauncherOne in the past year and extends the thinking of how commercial space, small satellites and this new emerging market can be brought to bear to enable true space system resiliency.

  17. Dedicated Operating Room Teams and Clinical Outcomes in an Enhanced Recovery after Surgery Pathway for Colorectal Surgery.

    Science.gov (United States)

    Grant, Michael C; Hanna, Andrew; Benson, Andrew; Hobson, Deborah; Wu, Christopher L; Yuan, Christina T; Rosen, Michael; Wick, Elizabeth C

    2018-03-01

    Our aim was to determine whether the establishment of a dedicated operating room team leads to improved process measure compliance and clinical outcomes in an Enhanced Recovery after Surgery (ERAS) program. Enhanced Recovery after Surgery programs involve the application of bundled best practices to improve the value of perioperative care. Successful implementation and sustainment of ERAS programs has been linked to compliance with protocol elements. Development of dedicated teams of anesthesia providers was a component of ERAS implementation. Intraoperative provider team networks (surgeons, anesthesiologists, and certified registered nurse anesthetists) were developed for all cases before and after implementation of colorectal ERAS. Four measures of centrality were analyzed in each network based on case assignments, and these measures were correlated with both rates of process measure compliance and clinical outcomes. Enhanced Recovery after Surgery provider teams led to a decrease in the closeness of anesthesiologists (p = 0.04) and significant increase in the clustering coefficient of certified registered nurse anesthetists (p = 0.005) compared with the pre-ERAS network. There was no significant change in centrality among surgeons (p = NS for all measures). Enhanced Recovery after Surgery designation among anesthesiologists and nurse anesthetists-whereby individual providers received an in-service on protocol elements and received compliance data was strongly associated with high compliance (>0.6 of measures; p < 0.001 for each group). In addition, high compliance was associated with a significant reduction in length of stay (p < 0.01), surgical site infection (p < 0.002), and morbidity (p < 0.009). Dedicated operating room teams led to increased centrality among anesthesia providers, which in turn not only increased compliance, but also improved several clinical outcomes. Copyright © 2017 American College of Surgeons. Published by Elsevier Inc. All rights

  18. Prospects for dedicated energy crop production and attitudes towards agricultural straw use: The case of livestock farmers

    International Nuclear Information System (INIS)

    Wilson, P.; Glithero, N.J.; Ramsden, S.J.

    2014-01-01

    Second generation biofuels utilising agricultural by-products (e.g. straw), or dedicated energy crops (DECs) produced on ‘marginal’ land, have been called for. A structured telephone survey of 263 livestock farmers, predominantly located in the west or ‘marginal’ upland areas of England captured data on attitudes towards straw use and DECs. Combined with farm physical and business data, the survey results show that 7.2% and 6.3% of farmers would respectively consider growing SRC and miscanthus, producing respective maximum potential English crop areas of 54,603 ha and 43,859 ha. If higher market prices for straw occurred, most livestock farmers would continue to buy straw. Reasons for not being willing to consider growing DECs include concerns over land quality, committing land for a long time period, lack of appropriate machinery, profitability, and time to financial return; a range of moral, land quality, production conflict and lack of crop knowledge factors were also cited. Results demonstrate limited potential for the production of DECs on livestock farms in England. Changes in policy support to address farmer concerns with respect to DECs will be required to incentivise farmers to increase energy crop production. Policy support for DEC production must be cognisant of farm-level economic, tenancy and personal objectives. - Highlights: • Survey of English livestock farms determining attitudes to dedicated energy crops. • 6.3% to 7.2% of surveyed farmers would consider growing energy crops. • Limited potential for dedicated energy crops on livestock farms in England. • Livestock farmers would continue to buy straw, even at higher market prices. • Wide range of reasons given for farmers’ decisions related to energy crops

  19. Interpretation of digital breast tomosynthesis: preliminary study on comparison with picture archiving and communication system (PACS) and dedicated workstation.

    Science.gov (United States)

    Kim, Young Seon; Chang, Jung Min; Yi, Ann; Shin, Sung Ui; Lee, Myung Eun; Kim, Won Hwa; Cho, Nariya; Moon, Woo Kyung

    2017-08-01

    To compare the diagnostic accuracy and efficiency in the interpretation of digital breast tomosynthesis (DBT) images using a picture archiving and communication system (PACS) and a dedicated workstation. 97 DBT images obtained for screening or diagnostic purposes were stored in both a workstation and a PACS and evaluated in combination with digital mammography by three independent radiologists retrospectively. Breast Imaging-Reporting and Data System final assessments and likelihood of malignancy (%) were assigned and the interpretation time when using the workstation and PACS was recorded. Receiver operating characteristic curve analysis, sensitivities and specificities were compared with histopathological examination and follow-up data as a reference standard. Area under the receiver operating characteristic curve values for cancer detection (0.839 vs 0.815, p = 0.6375) and sensitivity (81.8% vs 75.8%, p = 0.2188) showed no statistically significant differences between the workstation and PACS. However, specificity was significantly higher when analysing on the workstation than when using PACS (83.7% vs 76.9%, p = 0.009). When evaluating DBT images using PACS, only one case was deemed necessary to be reanalysed using the workstation. The mean time to interpret DBT images on PACS (1.68 min/case) was significantly longer than that to interpret on the workstation (1.35 min/case) (p < 0.0001). Interpretation of DBT images using PACS showed comparable diagnostic performance to a dedicated workstation, even though it required a longer reading time. Advances in knowledge: Interpretation of DBT images using PACS is an alternative to evaluate the images when a dedicated workstation is not available.

  20. THE INFORMATION MODEL «SOCIAL EXPLOSION»

    Directory of Open Access Journals (Sweden)

    Alexander Chernyavskiy

    2012-01-01

    Full Text Available Article is dedicated to examination and analysis of the construction of the information model «social explosion», which corresponds to the newest «colored» revolutions. The analysis of model makes it possible to see effective approaches to the initiation of this explosion and by the use of contemporary information communications as honeycomb connection and the mobile Internet

  1. The QUANTUM I project: Parallel processing in a local area network work dedicated to ab initio calculation of potential hypersurfaces

    International Nuclear Information System (INIS)

    Lavenir, E.; Pic, J.M.; Alibran, P.; Leclercq, J.M.

    1987-01-01

    The QUANTUM I project is a three-stage device. The stages are respectively dedicated to particular steps of the ab initio determination of a point on the hypersurface. The first stage deals with the computation of the integrals between the basis functions, the second with the S.C.F. (or M.C.S.C.F.) process and the third with the C.I treatment. Each step is developed in terms of parallel mode (M.I.M.D.), the whole device working following a pipeline mode: the three stages works simultaneously for different points

  2. Development of a dedicated isotope mass spectrometer for the noninvasive diagnostics of humans infected with Helicobacter Pylori

    Science.gov (United States)

    Blashenkov, N. M.; Sheshenya, E. S.; Solov'ev, S. M.; Gall', L. N.; Sachenko, V. M.; Zarutskii, I. V.; Gall', N. R.

    2013-06-01

    A dedicated isotope mass spectrometer for the noninvasive diagnostics of humans infected with Helicobacter Pylori using the isotope respiratory test is developed. A low-aberration mass analyzer is calculated, an input system that makes it possible to eliminate the memory effects is developed, and a small-size ion detector is constructed. The mass spectrometer is created, and the tests are performed. The measurement accuracy of the 13C/12C and 16O/18O isotope ratios are 1.7 and 2.2‰, respectively. Preliminary medical tests show that the spectrometer can be employed for the desired diagnostics.

  3. Exploring the world with the laser dedicated to Theodor Hänsch on his 75th birthday

    CERN Document Server

    Udem, Thomas; Esslinger, Tilman

    2018-01-01

    This edition contains carefully selected contributions by leading scientists in high-resolution laser spectroscopy, quantum optics and laser physics. Emphasis is given to ultrafast laser phenomena, implementations of frequency combs, precision spectroscopy and high resolution metrology. Furthermore, applications of the fundamentals of quantum mechanics are widely covered. This book is dedicated to Nobel prize winner Theodor W. Hänsch on the occasion of his 75th birthday. The contributions are reprinted from a topical collection published in Applied Physics B, 2016.

  4. Total Protein Content Determination of Microalgal Biomass by Elemental Nitrogen Analysis and a Dedicated Nitrogen-to-Protein Conversion Factor

    Energy Technology Data Exchange (ETDEWEB)

    Laurens, Lieve M [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Olstad-Thompson, Jessica L [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Templeton, David W [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2018-04-02

    Accurately determining protein content is important in the valorization of algal biomass in food, feed, and fuel markets, where these values are used for component balance calculations. Conversion of elemental nitrogen to protein is a well-accepted and widely practiced method, but depends on developing an applicable nitrogen-to-protein conversion factor. The methodology reported here covers the quantitative assessment of the total nitrogen content of algal biomass and a description of the methodology that underpins the accurate de novo calculation of a dedicated nitrogen-to-protein conversion factor.

  5. e-Drug3D: 3D structure collections dedicated to drug repurposing and fragment-based drug design.

    Science.gov (United States)

    Pihan, Emilie; Colliandre, Lionel; Guichou, Jean-François; Douguet, Dominique

    2012-06-01

    In the drug discovery field, new uses for old drugs, selective optimization of side activities and fragment-based drug design (FBDD) have proved to be successful alternatives to high-throughput screening. e-Drug3D is a database of 3D chemical structures of drugs that provides several collections of ready-to-screen SD files of drugs and commercial drug fragments. They are natural inputs in studies dedicated to drug repurposing and FBDD. e-Drug3D collections are freely available at http://chemoinfo.ipmc.cnrs.fr/e-drug3d.html either for download or for direct in silico web-based screenings.

  6. High-resolution magnetic resonance angiography of the lower extremities with a dedicated 36-element matrix coil at 3 Tesla.

    Science.gov (United States)

    Kramer, Harald; Michaely, Henrik J; Matschl, Volker; Schmitt, Peter; Reiser, Maximilian F; Schoenberg, Stefan O

    2007-06-01

    Recent developments in hard- and software help to significantly increase image quality of magnetic resonance angiography (MRA). Parallel acquisition techniques (PAT) help to increase spatial resolution and to decrease acquisition time but also suffer from a decrease in signal-to-noise ratio (SNR). The movement to higher field strength and the use of dedicated angiography coils can further increase spatial resolution while decreasing acquisition times at the same SNR as it is known from contemporary exams. The goal of our study was to compare the image quality of MRA datasets acquired with a standard matrix coil in comparison to MRA datasets acquired with a dedicated peripheral angio matrix coil and higher factors of parallel imaging. Before the first volunteer examination, unaccelerated phantom measurements were performed with the different coils. After institutional review board approval, 15 healthy volunteers underwent MRA of the lower extremity on a 32 channel 3.0 Tesla MR System. In 5 of them MRA of the calves was performed with a PAT acceleration factor of 2 and a standard body-matrix surface coil placed at the legs. Ten volunteers underwent MRA of the calves with a dedicated 36-element angiography matrix coil: 5 with a PAT acceleration of 3 and 5 with a PAT acceleration factor of 4, respectively. The acquired volume and acquisition time was approximately the same in all examinations, only the spatial resolution was increased with the acceleration factor. The acquisition time per voxel was calculated. Image quality was rated independently by 2 readers in terms of vessel conspicuity, venous overlay, and occurrence of artifacts. The inter-reader agreement was calculated by the kappa-statistics. SNR and contrast-to-noise ratios from the different examinations were evaluated. All 15 volunteers completed the examination, no adverse events occurred. None of the examinations showed venous overlay; 70% of the examinations showed an excellent vessel conspicuity

  7. Supercavitation Advances and Perspectives A collection dedicated to the 70th jubilee of YuN Savchenko

    CERN Document Server

    2012-01-01

    This collection is dedicated to the 70th jubilee of Yu. N. Savchenko, and presents experimental, theoretical, and numerical investigations written by an international group of well-known authors. The contributions solve very important problems of the high-speed hydrodynamics, such as supersonic motion in water, drag diminishing, dynamics and stability of supercavitating vehicles, water entry and hydrodynamic performances of hydrofoils, ventilated cavities after a disc and under the ship bottom. The  book is written for researches, scientists, engineers, and students interested in problems of hydromechanics.

  8. X-ray stereotactic lesion localization in conjunction with dedicated scintimammography

    Energy Technology Data Exchange (ETDEWEB)

    Mitali J. More; Deepa Narayanan; Patricia J. Goodale; Stanislaw Majewski; Benjamin Welch; Randolph Wojcik; Mark Williams

    2003-10-01

    We are developing a dual modality system that combines digital X-ray mammography with gamma emission scintigraphy on an upright mammography gantry. The breast is held under mild compression by a support structure that is independent of the detectors. The X-ray source and detectors can be rotated around a fixed rotation axis permitting multiple views of the breast with fixed compression. Two such views can be combined as a stereotactic pair to obtain the three-dimensional location of breast lesions. Information about the location of the lesion within the breast permits corrections for attenuation and detector spatial resolution, resulting in more accurate estimation of the true lesion-to-background concentration ratio, based on the image lesion-to-background counts ratio. In this paper, we describe the model used to make these corrections, and present the results of the phantom experiments designed to test the accuracy of our calculations.

  9. Clodoaldo Beckmann (1927–2007: The surgeon and documentalist dedicated to Librarianship

    Directory of Open Access Journals (Sweden)

    Orinete Costa Souza

    2015-10-01

    Full Text Available Study about the life and work of the surgeon and documentalist Clodoaldo Fernando Ribeiro Beckmann (1927-2007, founder of the Librarianship at the Universidade Federal do Pará (UFPA. It has the objective of recover the professional dimension of the man who has put his knowledge at service of the Medicine and Librarianship a study of qualitative nature was conducted, it was based on oral history, more precisely by biographic method, allied to documental and bibliographic research and the realization of open interviews and informal conversations with relatives, friends and ex-students. The memory recovered by evidences point the remarkable accomplishments of the Beckmann’s life that made his name entered into the history of Medicine and Librarianship in Pará

  10. PET with a dual-head coincidence gamma camera in head and neck cancer: A comparison with computed tomography and dedicated PET

    International Nuclear Information System (INIS)

    Zimny, M.

    2001-01-01

    Positron emission tomography with 18 F-fluoro-deoxyglucose (FDG PET) is a promising imaging tool for detecting and staging of primary or recurrent head and neck cancer. The aim of this study was to evaluate a dual-head gamma camera modified for coincidence detection (KGK-PET) in comparison to computed tomography (CT) and dedicated PET (dPET). 50 patients with known or suspected primary or recurrent head and neck cancer were enrolled. 32 patients underwent KGK-PET and dPET using a one-day protocol. The sensitivity for the detection of primary/ recurrent head and neck cancer for KGK-PET and CT was 80% and 54%, respectively, specificity was 73% and 82%, respectively. The sensitivity and specificity for the detection of lymph node metastases based on neck sides with KGK-PET was 71% (CT: 65%) and 88% (CT: 89%) respectively. In comparison to dPET, KGK-PET revealed concordant results in 32/32 patients with respect to primary tumor/recurrent disease and in 55/60 evaluated neck sides. All involved neck sides that were missed by KGK-PET were also negative with dPET. These results indicate that in patients with head and neck cancer KGK-PET reveals information, that are similar to dPET and complementary to CT. (orig.) [de

  11. SPIROC (SiPM Integrated Read-Out Chip) Dedicated very front-end electronics for an ILC prototype hadronic calorimeter with SiPM read-out

    CERN Document Server

    Bouchel, Michel; Dulucq, Frédéric; Fleury, Julien; de La Taille, Christophe; Martin-Chassard, Gisèle; Raux, Ludovic

    2009-01-01

    The SPIROC chip is a dedicated very front-end electronics for an ILC prototype hadronic calorimeter with Silicon photomultiplier (or MPPC) readout. This ASIC is due to equip a 10,000-channel demonstrator in 2009. SPIROC is an evolution of FLC_SiPM used for the ILC AHCAL physics prototype [1]. SPIROC was submitted in June 2007 and will be tested in September 2007. It embeds cutting edge features that fulfil ILC final detector requirements. It has been realized in 0.35m SiGe technology. It has been developed to match the requirements of large dynamic range, low noise, low consumption, high precision and large number of readout channels needed. SPIROC is an auto-triggered, bi-gain, 36-channel ASIC which allows to measure on each channel the charge from one photoelectron to 2000 and the time with a 100ps accurate TDC. An analogue memory array with a depth of 16 for each channel is used to store the time information and the charge measurement. A 12-bit Wilkinson ADC has been embedded to digitize the analogue memor...

  12. SPIROC (SiPM Integrated Read-Out Chip) Dedicated very front-end electronics for an ILC prototype hadronic calorimeter with SiPM read-out

    CERN Document Server

    Bouchel, Michel; Fleury, Julien; de La Taille, Christophe; Martin-Chassard, Gisèle; Raux, Ludovic

    2007-01-01

    The SPIROC chip is a dedicated very front-end electronics for an ILC prototype hadronic calorimeter with Silicon photomultiplier (or MPPC) readout. This ASIC is due to equip a 10,000-channel demonstrator in 2009. SPIROC is an evolution of FLC_SiPM used for the ILC AHCAL physics prototype [1]. SPIROC was submitted in June 2007 and will be tested in September 2007. It embeds cutting edge features that fulfil ILC final detector requirements. It has been realized in 0.35m SiGe technology. It has been developed to match the requirements of large dynamic range, low noise, low consumption, high precision and large number of readout channels needed. SPIROC is an auto-triggered, bi-gain, 36-channel ASIC which allows to measure on each channel the charge from one photoelectron to 2000 and the time with a 100ps accurate TDC. An analogue memory array with a depth of 16 for each channel is used to store the time information and the charge measurement. A 12-bit Wilkinson ADC has been embedded to digitize the analogue memor...

  13. In vivo assessment of 111In labelled lymphocyte gut homing in a TNBS colitis mouse model determined by dedicated animal pinhole SPECT

    International Nuclear Information System (INIS)

    Bennink, R.J.; Bruin, C.M. de; Montfrans, C. van; Jonge, W.J. de; Deventer, S.J. van; Velde, A.A. te

    2002-01-01

    Aims: The increasing knowledge of the molecular basis of leukocyte trafficking results in the development of novel anti-inflammatory strategies for inflammatory bowel disease (IBD). For optimal evaluation of therapy efficacy, information about inflammatory activity in bowel segments or lymphocyte recirculation and kinetics in the follow-up of experimental treatment for IBD is needed. The aim of this study was to evaluate a non-invasive scintigraphic technique, able to assess lymphocyte trafficking in a trinitrobenzene sulfonic acid (TNBS) induced mouse colitis model of IBD. Materials and Methods: TNBS sensitised and non-sensitised murine total splenocytes, isolated from donor TNBS colitis or placebo treated BALB/c mice, were labelled in vitro with 111 In-oxine and injected intravenously into recipient BALB/c mice with TNBS-induced colitis or healthy BALB/c mice instilled with saline. Biodistribution and specific radioactive uptake, representing transferred cells, was determined by serial dedicated animal planar scintigraphy and pinhole SPECT of the abdomen 4, 24 and 48h post injection of labelled cells. Moreover, the severity of inflammation in recipient mice was determined by histological scoring. Results: Lymphocyte migration to the inflamed colon of recipient mice increased in time and was maximal at 48h after administration of the 111 In-oxine labelled donor splenocytes. The highest specific radioactive uptake ratio in the colon after 48h was observed in recipient mice with TNBS colitis that received TNBS sensitised lymphocytes (saline vs. TNBS colitis resp. 0.22 ± 0.035 and 0.51 ± 0.033 mean ± SEM p<0.01). Histological scoring confirmed colitis in the TNBS colitis recipient groups and excluded colitis in the saline instilled recipient groups. TNBS colitis recipient mice that received sensitised lymphocytes had a more severe colitis upon histological evaluation as compared with TNBS colitis recipient mice receiving non-sensitised cells (mean histological

  14. Playing to your skills: a randomised controlled trial evaluating a dedicated video game for minimally invasive surgery.

    Science.gov (United States)

    Harrington, Cuan M; Chaitanya, Vishwa; Dicker, Patrick; Traynor, Oscar; Kavanagh, Dara O

    2018-02-14

    Video gaming demands elements of visual attention, hand-eye coordination and depth perception which may be contiguous with laparoscopic skill development. General video gaming has demonstrated altered cortical plasticity and improved baseline/acquisition of minimally invasive skills. The present study aimed to evaluate for skill acquisition associated with a commercially available dedicated laparoscopic video game (Underground) and its unique (laparoscopic-like) controller for the Nintendo®Wii U™ console. This single-blinded randomised controlled study was conducted with laparoscopically naive student volunteers of limited (Virtual Reality (VR) simulator (LAP Mentor TM , 3D systems, Colorado, USA). Twenty participants were randomised to two groups; Group A was requested to complete 5 h of video gaming (Underground) per week and Group B to avoid gaming beyond their normal frequency. After 4 weeks participants were reassessed using the same VR tasks. Changes in simulator performances were assessed for each group and for intergroup variances using mixed model regression. Significant inter- and intragroup performances were present for the video gaming and controls across four basic tasks. The video gaming group demonstrated significant improvements in thirty-one of the metrics examined including dominant (p ≤ 0.004) and non-dominant (p entertainment distractions (11.1%). Our work revealed significant value in training using a dedicated laparoscopic video game for acquisition of virtual laparoscopic skills. This novel serious game may provide foundations for future surgical developments on game consoles in the home environment.

  15. Multicenter study for the evaluation of a dedicated biopsy device for MR-guided vacuum biopsy of the breast

    International Nuclear Information System (INIS)

    Perlet, C.; Sittek, H.; Schneider, P.; Reiser, M.; Heinig, A.; Stets, C.; Heywang-Koebrunner, S.H.; Prat, X.; Lamarque, J.; Taourel, P.; Casselman, J.; Baath, L.; Anderson, I.

    2002-01-01

    The purpose of this multicenter study was to determine the accuracy and clinical value of a dedicated breast biopsy system which allows for MR-guided vacuum biopsy (VB) of contrast-enhancing lesions. In five European centers, MR-guided 11-gauge VB was performed on 341 lesions. In 7 cases VB was unsuccessful. This was immediately realized on postinterventional images or direct follow-up combined with histopathology-imaging correlation; thus, a false-negative diagnosis was avoided. Histology of 334 successful biopsies yielded 84 (25%) malignancies, 17 (5%) atypical ductal hyperplasias, and 233 (70%) benign entities. Verification of malignant or borderline lesions included reexcision of the biopsy cavity. Benign histologic biopsy results were verified by retrospective correlation with the pre- and postinterventional MRI and by subsequent follow-up. Our results indicate that MR-guided VB, in combination with the dedicated biopsy coil, offers the possibility to accurately diagnose even very small lesions that can only be visualized or localized by MRI. (orig.)

  16. Dynamic and quantitative evaluation of degenerative mitral valve disease: a dedicated framework based on cardiac magnetic resonance imaging.

    Science.gov (United States)

    Sturla, Francesco; Onorati, Francesco; Puppini, Giovanni; Pappalardo, Omar A; Selmi, Matteo; Votta, Emiliano; Faggian, Giuseppe; Redaelli, Alberto

    2017-04-01

    Accurate quantification of mitral valve (MV) morphology and dynamic behavior over the cardiac cycle is crucial to understand the mechanisms of degenerative MV dysfunction and to guide the surgical intervention. Cardiac magnetic resonance (CMR) imaging has progressively been adopted to evaluate MV pathophysiology, although a dedicated framework is required to perform a quantitative assessment of the functional MV anatomy. We investigated MV dynamic behavior in subjects with normal MV anatomy (n=10) and patients referred to surgery due to degenerative MV prolapse, classified as fibro-elastic deficiency (FED, n=9) and Barlow's disease (BD, n=10). A CMR-dedicated framework was adopted to evaluate prolapse height and volume and quantitatively assess valvular morphology and papillary muscles (PAPs) function over the cardiac cycle. Multiple comparison was used to investigate the hallmarks associated to MV degenerative prolapse and evaluate the feasibility of anatomical and functional distinction between FED and BD phenotypes. On average, annular dimensions were significantly (Pframework allows for the quantitative and dynamic evaluation of MV apparatus, with quantifiable annular alterations representing the primary hallmark of severe MV degeneration. This may aid surgeons in the evaluation of the severity of MV dysfunction and the selection of the appropriate MV treatment.

  17. Quantifying the Effects of Biomass Market Conditions and Policy Incentives on Economically Feasible Sites to Establish Dedicated Energy Crops

    Directory of Open Access Journals (Sweden)

    Sandhya Nepal

    2015-11-01

    Full Text Available This study used a spatially-explicit model to identify the amount and spatial distribution of economically feasible sites for establishing dedicated energy crops under various market and policy scenarios. A sensitivity analysis was performed for a biomass market with different discount rates and biomass prices as well as policy scenarios including propriety tax exemption, carbon offset payments, and the inclusion of farmland for biomass production. The model was applied to a four-county study area in Kentucky representing conditions commonly found in the Ohio River Valley. Results showed that both biomass price and discount rate have a can strongly influence the amount of economically efficient sites. Rising the biomass price by 5 $·t−1 and lowering discount rate by 1% from the baseline scenario (40 $·t−1 and 5% resulted in an over fourteen fold increment. Property tax exemption resulted in a fourfold increase, a carbon payment on only 1 $·t−1 caused a twelve fold increase and extending the landbase from marginal land to farmland only slightly increase the economically efficient sites. These results provide an objective evaluation of market and policy scenarios in terms of their potential to increase land availability for establishing dedicated energy crops and to promote the bioenergy industry.

  18. Feasibility analysis of the Primary Loop of Pool-Type Natural Circulating Nuclear Reactor Dedicated to Seawater Desalination

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, Woonho; Jeong, Yong Hoon [KAIST, Daejeon (Korea, Republic of)

    2016-05-15

    In this study, the feasibility of natural circulation was evaluated for the reference plant AHR400 (Advanced Heating Reactor 400MWth). AHR400 is a pool-type desalination-dedicated nuclear reactor. As a consequence, AHR400 has low operating pressure and temperature which provides large safety margin. Removal of the reactor coolant pump from the AHR400 will enforce integrity of the reactor vessel and passive safety feature. Therefore, the study also tried to find out optimized primary loop design to achieve total natural circulation of the coolant. Natural circulation capacity of the primary loop of the desalination dedicated nuclear reactor AHR400 was evaluated. It was concluded that to remove RCP from the AHR400 and operates the reactor only by natural circulation of the coolant is impossible. Decreased core power as half make removal of RCP possible with 15m central height difference between the core and IHXs. Furthermore, validation and modification of pressure loss coefficients by small-scaled natural circulation experiment at a pool-type reactor would provide more accurate results.

  19. First clinical experience with a dedicated MRI-guided high-intensity focused ultrasound system for breast cancer ablation

    Energy Technology Data Exchange (ETDEWEB)

    Merckel, Laura G.; Knuttel, Floor M.; Peters, Nicky H.G.M.; Mali, Willem P.T.M.; Bosch, Maurice A.A.J. van den [University Medical Center Utrecht, Department of Radiology, HP E 01.132, Utrecht (Netherlands); Deckers, Roel; Moonen, Chrit T.W.; Bartels, Lambertus W. [University Medical Center Utrecht, Image Sciences Institute, Utrecht (Netherlands); Dalen, Thijs van [Diakonessenhuis Utrecht, Department of Surgery, Utrecht (Netherlands); Schubert, Gerald [Philips Healthcare, Best (Netherlands); Weits, Teun [Diakonessenhuis Utrecht, Department of Radiology, Utrecht (Netherlands); Diest, Paul J. van [University Medical Center Utrecht, Department of Pathology, Utrecht (Netherlands); Vaessen, Paul H.H.B. [University Medical Center Utrecht, Department of Anesthesiology, Utrecht (Netherlands); Gorp, Joost M.H.H. van [Diakonessenhuis Utrecht, Department of Pathology, Utrecht (Netherlands)

    2016-11-15

    To assess the safety and feasibility of MRI-guided high-intensity focused ultrasound (MR-HIFU) ablation in breast cancer patients using a dedicated breast platform. Patients with early-stage invasive breast cancer underwent partial tumour ablation prior to surgical resection. MR-HIFU ablation was performed using proton resonance frequency shift MR thermometry and an MR-HIFU system specifically designed for breast tumour ablation. The presence and extent of tumour necrosis was assessed by histopathological analysis of the surgical specimen. Pearson correlation coefficients were calculated to assess the relationship between sonication parameters, temperature increase and size of tumour necrosis at histopathology. Ten female patients underwent MR-HIFU treatment. No skin redness or burns were observed in any of the patients. No correlation was found between the applied energy and the temperature increase. In six patients, tumour necrosis was observed with a maximum diameter of 3-11 mm. In these patients, the number of targeted locations was equal to the number of areas with tumour necrosis. A good correlation was found between the applied energy and the size of tumour necrosis at histopathology (Pearson = 0.76, p = 0.002). Our results show that MR-HIFU ablation with the dedicated breast system is safe and results in histopathologically proven tumour necrosis. (orig.)

  20. Contribution to the study of wettability in a pulsed column dedicated to the production of a precipitate

    International Nuclear Information System (INIS)

    Picard, R.

    2011-01-01

    The process dedicated to the oxalic precipitation of plutonium is very sensitive to the high sticking behavior of the produced precipitates. Therefore, the laboratory of 'Genie Chimique et Instrumentation' based in Marcoule in France puts forward the idea of carrying out the process in a pulsed column. In this way, the precipitate is confined inside in the droplets of the emulsion, far from the surfaces of the apparatus. Nevertheless, if those surfaces are made of stainless steel, the fouling of the column is inevitably observed. The thesis also introduces the concepts and tools dedicated to a fine understanding of the fouling issue. Though the work carried out scans the whole issue, the thesis mainly focuses on drop bouncing. The results provide experimental data in a low studied configuration and target the key parameters driving the bounce. The practical applications of those results point out that using an un-optimized stainless steel pulsed column for the precipitation of radionuclides does not prevent from fouling. The process could still be carried out using another technology patented during the PhD. This last point needs more investigations. Especially, the CEA has to work on the scale-up steps to design an apparatus which could be able to process industrial flow rates. Besides, this might be an interesting issue in process engineering. (author) [fr

  1. First identification of the herpes simplex virus by skin-dedicated ex vivo fluorescence confocal microscopy during herpetic skin infections.

    Science.gov (United States)

    Cinotti, E; Perrot, J L; Labeille, B; Campolmi, N; Thuret, G; Naigeon, N; Bourlet, T; Pillet, S; Cambazard, F

    2015-06-01

    Skin-dedicated ex vivo fluorescence confocal microscopy (FCM) has so far been used to identify cutaneous tumours on freshly excised samples using acridine orange as fluorochrome. To use FCM for a new indication, namely, the identification of the herpes simplex virus (HSV) in skin lesions, using fluorescent antibodies. Six roof samples from skin vesicles suspicious for HSV lesions were incubated with anti-HSV-1 and anti-HSV-2 antibodies coupled with fluorescein isothiocyanate, and examined under skin-dedicated ex vivo FCM. The positive controls were swabs taken from the floor of each vesicle and observed under conventional direct fluorescence assay (DFA) and by viral cultures. Roof samples from three bullae of bullous pemphigoid were the negative controls. Using ex vivo FCM, the samples from the lesions clinically suspicious for HSV infection were seen to be fluorescent after incubation with anti-HSV-1, and were negative after incubation with anti-HSV-2 antibodies. Conventional DFA with an optical microscope and cultures confirmed the presence of HSV-1 infection. By using fluorescent antibodies to identify precise structures, ex vivo FCM can be used for indications other than tumour identification. More specifically, it can be an additional diagnostic tool for HSV infection. © 2014 British Association of Dermatologists.

  2. Validation of the U-238 inelastic scattering neutron cross section through the EXCALIBUR dedicated experiment

    Directory of Open Access Journals (Sweden)

    Leconte Pierre

    2017-01-01

    Full Text Available EXCALIBUR is an integral transmission experiment based on the fast neutron source produced by the bare highly enriched fast burst reactor CALIBAN, located in CEA/DAM Valduc (France. Two experimental campaigns have been performed, one using a sphere of diameter 17 cm and one using two cylinders of 17 cm diameter 9 cm height, both made of metallic Uranium 238. A set of 15 different dosimeters with specific threshold energies have been employed to provide information on the neutron flux attenuation as a function of incident energy. Measurements uncertainties are typically in the range of 0.5–3% (1σ. The analysis of these experiments is performed with the TRIPOLI4 continuous energy Monte Carlo code. A calculation benchmark with validated simplifications is defined in order to improve the statistical convergence under 2%. Various 238U evaluations have been tested: JEFF-3.1.1, ENDF/B-VII.1 and the IB36 evaluation from IAEA. A sensitivity analysis is presented to identify the contribution of each reaction cross section to the integral transmission rate. This feedback may be of interest for the international effort on 238U, through the CIELO project.

  3. Multichannel wearable system dedicated for simultaneous electroencephalography/near-infrared spectroscopy real-time data acquisitions

    Science.gov (United States)

    Lareau, Etienne; Lesage, Frederic; Pouliot, Philippe; Nguyen, Dang; Le Lan, Jerome; Sawan, Mohamad

    2011-09-01

    Functional neuroimaging is becoming a valuable tool in cognitive research and clinical applications. The clinical context brings specific constraints that include the requirement of a high channel count to cover the whole head, high sensitivity for single event detection, and portability for long-term bedside monitoring. For epilepsy and stroke monitoring, the combination of electroencephalography (EEG) and functional near-infrared spectroscopy (NIRS) is expected to provide useful clinical information, and efforts have been deployed to create prototypes able to simultaneously acquire both measurement modalities. However, to the best of our knowledge, existing systems lack portability, NIRS sensitivity, or have low channel count. We present a battery-powered, portable system with potentially up to 32 EEG channels, 32 NIRS light sources, and 32 detectors. Avalanche photodiodes allow for high NIRS sensitivity and the autonomy of the system is over 24 h. A reduced channel count prototype with 8 EEG channels, 8 sources, and 8 detectors was tested on phantoms. Further validation was done on five healthy adults using a visual stimulation protocol to detect local hemodynamic changes and visually evoked potentials. Results show good concordance with literature regarding functional activations and suggest sufficient performance for clinical use, provided some minor adjustments were made.

  4. Digital signal processing applied to crystal identification in Positron Emission Tomography dedicated to small animals

    International Nuclear Information System (INIS)

    Fontaine, Rejean; Viscogliosi, Nicolas; Semmaoui, Hicham; Belanger, Francois; Lemieux, Francois; Tetrault, Marc-Andre; Michaud, Jean-Baptiste; Berard, Philippe; Cadorette, Jules; Pepin, Catherine M.; Lecomte, Roger

    2007-01-01

    The recent introduction of all-digital electronic architecture in Positron Emission Tomography (PET) scanners, enables new paradigms to be explored for extracting relevant information from the detector signals, such as energy, time and crystal identification. The LabPET TM small animal scanner, which implements free-running 45-MHz sampling directly at the output of the charge sensitive preamplifiers, provides an excellent platform to test such advanced digital algorithms. A real-time identification method, based on an Auto-Regressive Moving-Average (ARMA) scheme, was tested for discriminating between LYSO (t r ∼40 ns) and LGSO (t r ∼65 ns) scintillators in phoswich detectors, coupled to a single Avalanche Photodiode (APD). Even with a low energy threshold of 250 keV applied individually, error rates 10%, typically with conventional analog pulse shape discrimination techniques. Such digital crystal identification techniques can be readily implemented with phoswich detectors for improving spatial resolution in PET, either by increasing crystal pixellization or by mitigating parallax errors through depth-of-interaction determination. It also allows to reduce the event rate presented to the real-time coincidence engine by applying a low energy limit at the crystal granularity and rejecting more Compton photons

  5. Digital signal processing applied to crystal identification in Positron Emission Tomography dedicated to small animals

    Energy Technology Data Exchange (ETDEWEB)

    Fontaine, Rejean [Department of Electrical and Computer Engineering, Universite de Sherbrooke, 2500 Boul. Universite, Sherbrooke, Que., J1 K 2R1 (Canada)]. E-mail: Rejean.Fontaine@Usherbrooke.ca; Viscogliosi, Nicolas [Department of Electrical and Computer Engineering, Universite de Sherbrooke, 2500 Boul. Universite, Sherbrooke, Que., J1 K 2R1 (Canada); Semmaoui, Hicham [Department of Electrical and Computer Engineering, Universite de Sherbrooke, 2500 Boul. Universite, Sherbrooke, Que., J1 K 2R1 (Canada); Belanger, Francois [Department of Electrical and Computer Engineering, Universite de Sherbrooke, 2500 Boul. Universite, Sherbrooke, Que., J1 K 2R1 (Canada); Lemieux, Francois [Department of Electrical and Computer Engineering, Universite de Sherbrooke, 2500 Boul. Universite, Sherbrooke, Que., J1 K 2R1 (Canada); Tetrault, Marc-Andre [Department of Electrical and Computer Engineering, Universite de Sherbrooke, 2500 Boul. Universite, Sherbrooke, Que., J1 K 2R1 (Canada); Michaud, Jean-Baptiste [Department of Electrical and Computer Engineering, Universite de Sherbrooke, 2500 Boul. Universite, Sherbrooke, Que., J1 K 2R1 (Canada); Berard, Philippe [Department of Nuclear Medicine and Radiobiology, Universite de Sherbrooke, 2500 Boul. Universite, Sherbrooke, Que., J1 K 2R1 (Canada); Cadorette, Jules [Department of Nuclear Medicine and Radiobiology, Universite de Sherbrooke, 2500 Boul. Universite, Sherbrooke, Que., J1 K 2R1 (Canada); Pepin, Catherine M. [Department of Nuclear Medicine and Radiobiology, Universite de Sherbrooke, 2500 Boul. Universite, Sherbrooke, Que., J1 K 2R1 (Canada); Lecomte, Roger [Department of Nuclear Medicine and Radiobiology, Universite de Sherbrooke, 2500 Boul. Universite, Sherbrooke, Que., J1 K 2R1 (Canada)

    2007-02-01

    The recent introduction of all-digital electronic architecture in Positron Emission Tomography (PET) scanners, enables new paradigms to be explored for extracting relevant information from the detector signals, such as energy, time and crystal identification. The LabPET{sup TM} small animal scanner, which implements free-running 45-MHz sampling directly at the output of the charge sensitive preamplifiers, provides an excellent platform to test such advanced digital algorithms. A real-time identification method, based on an Auto-Regressive Moving-Average (ARMA) scheme, was tested for discriminating between LYSO (t{sub r}{approx}40 ns) and LGSO (t{sub r}{approx}65 ns) scintillators in phoswich detectors, coupled to a single Avalanche Photodiode (APD). Even with a low energy threshold of 250 keV applied individually, error rates<4% can be achieved, as compared to >10%, typically with conventional analog pulse shape discrimination techniques. Such digital crystal identification techniques can be readily implemented with phoswich detectors for improving spatial resolution in PET, either by increasing crystal pixellization or by mitigating parallax errors through depth-of-interaction determination. It also allows to reduce the event rate presented to the real-time coincidence engine by applying a low energy limit at the crystal granularity and rejecting more Compton photons.

  6. Plagio e commercio nelle guide tardocinquecentesche dedicate a Napoli e Pozzuoli

    Directory of Open Access Journals (Sweden)

    Harald Hendrix

    2014-10-01

    Full Text Available Plagiarism and commerce in late sixteenth-century guides to the city of Naples and its districtThis essay illustrates how strongly chorographical texts depend on intertextual borrowings from previous materials, up to the point of becoming a patchwork of quotations from earlier texts. It highlights how this characteristic feature of chorography becomes the object of an unusually early debate on plagiarism. This polemic between two clearly competing Neapolitan intellectuals, Tomaso Costo and Scipione Mazzella, denotes how in the 1590s the status of chorography was changing considerably. Hendrix argues that the growing numbers of visitors to a city like Naples, particularly those coming from far away, lured publishers and authors alike as of the 1580s to transform conventional chorography conceived in a context of local pride into a commercially attractive product targeting this new audience. This went along with a re-framing of existing chorographical materials, not only causing concern with regard to its dubious status oscillating between intertextuality and plagiarism, but also in view of the urban identity presented no longer to wellinformed citizens but rather now to foreign visitors much more dependent on the accuracy and reliability of the given information.

  7. High-resolution magnetic resonance imaging of the anal sphincter using a dedicated endoanal receiver coil

    International Nuclear Information System (INIS)

    DeSouza, N.M.; Williams, A.D.; Gilderdale, D.J.

    1999-01-01

    The use of a surface coil in MR imaging improves signal-to-noise ratio of adjacent tissues of interest. We therefore devised an endoanal receiver coil for imaging the anal sphincter. The probe is solid and re-usable: it comprises a saddle geometry receiver with integral tuning, matching and decoupling. It is placed in the anal canal and immobilised externally. Both in vitro and in vivo normal anatomy is identified. The mucosa is high signal intensity, the submucosa low signal intensity, the internal sphincter uniformly high signal intensity and the external sphincter low signal intensity on T1- and T2-weighted images. In females, the transverse perineal muscle bridges the inferior part of the external sphincter anteriorly. In perianal sepsis, collections and the site of the endoanal opening are identified. In early-onset fecal incontinence following obstetric trauma/surgery, focal sphincter defects are demonstrated; in late-onset fecal incontinence external sphincter atrophy is seen. In fecally incontinent patients with scleroderma, forward deviation of the anterior sphincter musculature with descent of rectal air and feces into the anal canal is noted. The extent of sphincter invasion is assessed in low rectal tumours. In children with congenital anorectal anomalies, abnormalities of the muscle components are defined using smaller-diameter coils. Such information is invaluable in the assessment and surgical planning of patients with a variety of anorectal pathologies. (orig.)

  8. High-resolution magnetic resonance imaging of the anal sphincter using a dedicated endoanal receiver coil

    Energy Technology Data Exchange (ETDEWEB)

    DeSouza, N.M.; Williams, A.D.; Gilderdale, D.J. [Dept. of Radiology, Imperial College School of Medicine, London (United Kingdom)

    1999-04-01

    The use of a surface coil in MR imaging improves signal-to-noise ratio of adjacent tissues of interest. We therefore devised an endoanal receiver coil for imaging the anal sphincter. The probe is solid and re-usable: it comprises a saddle geometry receiver with integral tuning, matching and decoupling. It is placed in the anal canal and immobilised externally. Both in vitro and in vivo normal anatomy is identified. The mucosa is high signal intensity, the submucosa low signal intensity, the internal sphincter uniformly high signal intensity and the external sphincter low signal intensity on T1- and T2-weighted images. In females, the transverse perineal muscle bridges the inferior part of the external sphincter anteriorly. In perianal sepsis, collections and the site of the endoanal opening are identified. In early-onset fecal incontinence following obstetric trauma/surgery, focal sphincter defects are demonstrated; in late-onset fecal incontinence external sphincter atrophy is seen. In fecally incontinent patients with scleroderma, forward deviation of the anterior sphincter musculature with descent of rectal air and feces into the anal canal is noted. The extent of sphincter invasion is assessed in low rectal tumours. In children with congenital anorectal anomalies, abnormalities of the muscle components are defined using smaller-diameter coils. Such information is invaluable in the assessment and surgical planning of patients with a variety of anorectal pathologies. (orig.) With 15 figs., 26 refs.

  9. Validation of the U-238 inelastic scattering neutron cross section through the EXCALIBUR dedicated experiment

    Science.gov (United States)

    Leconte, Pierre; Bernard, David

    2017-09-01

    EXCALIBUR is an integral transmission experiment based on the fast neutron source produced by the bare highly enriched fast burst reactor CALIBAN, located in CEA/DAM Valduc (France). Two experimental campaigns have been performed, one using a sphere of diameter 17 cm and one using two cylinders of 17 cm diameter 9 cm height, both made of metallic Uranium 238. A set of 15 different dosimeters with specific threshold energies have been employed to provide information on the neutron flux attenuation as a function of incident energy. Measurements uncertainties are typically in the range of 0.5-3% (1σ). The analysis of these experiments is performed with the TRIPOLI4 continuous energy Monte Carlo code. A calculation benchmark with validated simplifications is defined in order to improve the statistical convergence under 2%. Various 238U evaluations have been tested: JEFF-3.1.1, ENDF/B-VII.1 and the IB36 evaluation from IAEA. A sensitivity analysis is presented to identify the contribution of each reaction cross section to the integral transmission rate. This feedback may be of interest for the international effort on 238U, through the CIELO project.

  10. Interactive simulation of nuclear power systems using a dedicated minicomputer - computer graphics facility

    International Nuclear Information System (INIS)

    Tye, C.; Sezgen, A.O.

    1980-01-01

    The design of control systems and operational procedures for large scale nuclear power plant poses a difficult optimization problem requiring a lot of computational effort. Plant dynamic simulation using digital minicomputers offers the prospect of relatively low cost computing and when combined with graphical input/output provides a powerful tool for studying such problems. The paper discusses the results obtained from a simulation study carried out at the Computer Graphics Unit of the University of Manchester using a typical station control model for an Advanced Gas Cooled reactor. Particular reference is placed on the use of computer graphics for information display, parameter and control system optimization and techniques for using graphical input for defining and/or modifying the control system topology. Experience gained from this study has shown that a relatively modest minicomputer system can be used for simulating large scale dynamic systems and that highly interactive computer graphics can be used to advantage to relieve the designer of many of the tedious aspects of simulation leaving him free to concentrate on the more creative aspects of his work. (author)

  11. Social Network Facebook in News: Comparisiion of Space Dedicated to Social Network Facebook ads its Content in Czech Media in the Years 2009 and 2011

    OpenAIRE

    Bezdíčková, Andrea

    2012-01-01

    Diploma thesis "Social Network Facebook in News: Comparison of Space Dedicated to Social Network Facebook and its Content in Czech Media in the Years 2009 and 2011", is dedicated to the way of use and citation of social network Facebook in the selected news media. The paper summarizes the establishment and strengthening of online media, particularly the phenomenon of social networks on the example of social network Facebook, and their influence on the transformation of the media sector, news ...

  12. Acknowledgements [3. international conference on small angle neutron scattering dedicated to the 80 anniversary of Yu.M. Ostanevich, Dubna (Russian Federation), 6-9 June 2016

    International Nuclear Information System (INIS)

    2017-01-01

    The Organizers of the III International Conference on Small Angle Neutron Scattering dedicated to the 80-th anniversary of Yu. M. Ostanevich, acknowledge the financial support from the Grants of the Governmental Plenipotentiary Representatives of Romania, Slovakia, Czech Republic, scientific projects of the Cooperation Programmes JINR-Romania. Special gratitude to the JINR and FLNP administration and staff is expressed. The conference is also dedicated to the 60th Anniversary of the Joint Institute for Nuclear Research, Dubna. (paper)

  13. The mini climatic city a dedicated space for technological innovations devoted to Sustainable City

    Science.gov (United States)

    Derkx, François; Lebental, Bérengère; Merliot, Erick; Dumoulin, Jean; Bourquin, Frédéric

    2015-04-01

    Our cities, from megalopolis to rural commune, are systems of an extraordinary technological and human complexity. Their balance is threatened by the growing population and rarefaction of resources. Massive urbanization endanges the environment, while global climate change, through natural hazards generated (climatic, hydrological and geological), threats people and goods. Connect the city, that is to say, design and spread systems able to route, between multiple actors, a very large amount of heterogeneous information natures and analyzed for various purposes, is at the heart of the hopes to make our cities more sustainable: climate-resilient, energy efficient and actresses of the energy transition, attractive to individuals and companies, health and environment friendly. If multiple players are already aware of this need, progress is slow because, beyond the only connectivity, it is the urban intelligence that will create the sustainable city, through coordinated capabilities of Perception, Decision and Action: to measure phenomena; to analyze their impact on urban sustainability in order to define strategies for improvement; to effectively act on the cause of the phenomenon. In this very active context with a strong societal impact, the Sense-City project aims to accelerate research and innovation in the field of sustainable city, particularly in the field of micro and nanosensors. The project is centered around a "mini climatic City", a unique mobile environmental chamber in Europe of 400m² that can accommodate realistic models of city main components, namely buildings, infrastructures, distribution networks or basements. This R&D test place, available in draft form from January 2015 and in finalized version in 2016, will allow to validate, in realistic conditions, innovative technologies performances for the sustainable city, especially micro- and nano-sensors, at the end of their development laboratory and upstream of industrialization. R & D platform

  14. [Enteroparasite determination in Lactuca sativa from farms dedicated to its production in Pasto, Colombia].

    Science.gov (United States)

    Polo, Giovanni Andrés; Benavides, Carmenza Janneth; Astaiza, Juan Manuel; Vallejo, Dario Antonio; Betancourt, Patricia

    2016-12-01

    Currently, vegetables like lettuce are widely recommended as part of the daily diet given their high nutritional value; however, while consumers feel attracted to the benefits provided by the vegetable, they may also be exposed to parasitic intestinal infections. To determine the presence or absence of enteroparasites in lettuce (Lactuca sativa) grown in the rural area in the municipality of Pasto, and to analyze associated factors based on the characterization of the lands. We conducted a descriptive double blind cross-sectional study. We took a total of 105 samples from 21 properties from June to December, 2013, and we processed them by sedimentation and flotation tests. Additionally, the owners were surveyed in order to obtain information about the possible variables influencing the occurrence of enteroparasites. We detected contamination in 100% of the lettuce samples and we found parasite eggs and larvae as follows: 95.25% with Entamoeba spp. cysts; 71.43% with Isospora spp. oocysts; 61.90% with Strongyloides stercoralis larvae (L3); 28.57% with Toxocara spp. eggs, and 4.76% with Eimeria spp. oocysts. Using the chi-square test we found association between Entamoeba spp. and ditches (p=0.008), dogs (p=0.008) and septic tanks (p=0.029); between Isospora spp. and compost (p=0.0001), dogs (p=0.0001) and slugs (p=0.002); between S. stercoralis and handling (p=0.003), and between Toxocara spp. and no use of biodigesters (p= 0.002). We found contamination with enteroparasites in lettuce samples from growing areas in the municipality of Pasto with animal and human sources as their main reservoirs, although others were present in the environment.

  15. A prototype PET/SPECT/X-rays scanner dedicated for whole body small animal studies.

    Science.gov (United States)

    Rouchota, Maritina; Georgiou, Maria; Fysikopoulos, Eleftherios; Fragogeorgi, Eirini; Mikropoulos, Konstantinos; Papadimitroulas, Panagiotis; Kagadis, George; Loudos, George

    2017-01-01

    To present a prototype tri-modal imaging system, consisting of a single photon emission computed tomography (SPET), a positron emission tomography (PET), and a computed tomography (CT) subsystem, evaluated in planar mode. The subsystems are mounted on a rotating gantry, so as to be able to allow tomographic imaging in the future. The system, designed and constructed by our group, allows whole body mouse imaging of competent performance and is currently, to the best of our knowledge, unequaled in a national and regional level. The SPET camera is based on two Position Sensitive Photomultiplier Tubes (PSPMT), coupled to a pixilated Sodium Iodide activated with Thallium (NaI(Tl)) scintillator, having an active area of 5x10cm 2 . The dual head PET camera is also based on two pairs of PSPMT, coupled to pixelated berillium germanium oxide (BGO) scintillators, having an active area of 5x10cm 2 . The X-rays system consists of a micro focus X-rays tube and a complementary metal-oxide-semiconductor (CMOS) detector, having an active area of 12x12cm 2 . The scintigraphic mode has a spatial resolution of 1.88mm full width at half maximum (FWHM) and a sensitivity of 107.5cpm/0.037MBq at the collimator surface. The coincidence PET mode has an average spatial resolution of 3.5mm (FWHM) and a peak sensitivity of 29.9cpm/0.037MBq. The X-rays spatial resolution is 3.5lp/mm and the contrast discrimination function value is lower than 2%. A compact tri-modal system was successfully built and evaluated for planar mode operation. The system has an efficient performance, allowing accurate and informative anatomical and functional imaging, as well as semi-quantitative results. Compared to other available systems, it provides a moderate but comparable performance, at a fraction of the cost and complexity. It is fully open, scalable and its main purpose is to support groups on a national and regional level and provide an open technological platform to study different detector components and

  16. Development, Dedication and Application of an Automatic Seismic Trip System for Nuclear Power Plants of Taiwan Power Company

    International Nuclear Information System (INIS)

    Liao, Hsin-kai; Lee, Chung-lin; Chen, Chang-kuo; Hsu, Yao-tung; Shyu, Shian-shing

    2011-01-01

    This paper describes the setups of Automatic Seismic Trip System (ASTS), including development, dedication and implementation, for Nuclear Power Plants (NPPs) of Taiwan Power Company (TPC). The purposed ASTS was designed to trip the reactor when big earthquake occurs. These ASTS were classified as class 1E equipment. They were developed and dedicated for safety applications in accordance with IEEE 323-1983, IEEE 344-1987, IEEE 383-1974 and Reg. Guide 1.180 R1. In order to meet the technical specification required by TPC, three sub-units in the ASTS were developed: Earthquake sensors: Kinemetrices FBA-23 triaxial accelerometers are selected since they were successfully used in Taiwan for seismic monitoring for more than 10 years. Signal conditioning module: It is designed to reduce noise from motion accelerometer (FBA-23) and then transmit seismic signal to the set-point and trip unit via instrument amplify circuit, 0.1 to 10Hz band pass filter circuit, absolute-value converter and voltage to current converter. Trip control module: after comparing the seismic signal level and set-point, the result will decide whether to drive the output relay or not. The output relay is used as the interface between ASTS and the reactor protection system in NPP. For the commercial grade item dedication for safety application, five processes were conducted. Those processes are Seismic test: to use plant specific required response spectrum (RRS), the test required spectrum should envelop RRS: Seismic auto-trip accuracy test: must not trip when filtered PA below set point minus 0.05g, and must trip when filtered PA exceeds set point over 0.05g. Trip signals occurred within 10 second interval are considered as same events: NEMA4 water proof test for sensor box: Anti-radiation test: 8.76x100 rads over 40 years: EMI/EMC test: follow RG 1.180 requirement. The ASTS were installed in three NPPs, six units in total, without connection to RPS in 2006. After one year reliable operation, the

  17. Information and Informality

    DEFF Research Database (Denmark)

    Larsson, Magnus; Segerstéen, Solveig; Svensson, Cathrin

    2011-01-01

    leaders on the basis of their possession of reliable knowledge in technical as well as organizational domains. The informal leaders engaged in interpretation and brokering of information and knowledge, as well as in mediating strategic values and priorities on both formal and informal arenas. Informal...... leaders were thus seen to function on the level of the organization as a whole, and in cooperation with formal leaders. Drawing on existing theory of leadership in creative and professional contexts, this cooperation can be specified to concern task structuring. The informal leaders in our study...... contributed to task structuring through sensemaking activities, while formal leaders focused on aspects such as clarifying output expectations, providing feedback, project structure, and diversity....

  18. Dedicated algorithm and software for the integrated analysis of AC and DC electrical outputs of piezoelectric vibration energy harvesters

    International Nuclear Information System (INIS)

    Kim, Jae Eum

    2014-01-01

    DC electrical outputs of a piezoelectric vibration energy harvester by nonlinear rectifying circuitry can hardly be obtained either by any mathematical models developed so far or by finite element analysis. To address the issue, this work used an equivalent electrical circuit model and newly developed an algorithm to efficiently identify relevant circuit parameters of arbitrarily-shaped cantilevered piezoelectric energy harvesters. The developed algorithm was then realized as a dedicated software module by adopting ANSYS finite element analysis software for the parameters identification and the Tcl/Tk programming language for a graphical user interface and linkage with ANSYS. For verifications, various AC electrical outputs by the developed software were compared with those by traditional finite element analysis. DC electrical outputs through rectifying circuitry were also examined for varying values of the smoothing capacitance and load resistance.

  19. Dedicated algorithm and software for the integrated analysis of AC and DC electrical outputs of piezoelectric vibration energy harvesters

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jae Eum [Catholic University of Daegu, Gyeongsan (Korea, Republic of)

    2014-10-15

    DC electrical outputs of a piezoelectric vibration energy harvester by nonlinear rectifying circuitry can hardly be obtained either by any mathematical models developed so far or by finite element analysis. To address the issue, this work used an equivalent electrical circuit model and newly developed an algorithm to efficiently identify relevant circuit parameters of arbitrarily-shaped cantilevered piezoelectric energy harvesters. The developed algorithm was then realized as a dedicated software module by adopting ANSYS finite element analysis software for the parameters identification and the Tcl/Tk programming language for a graphical user interface and linkage with ANSYS. For verifications, various AC electrical outputs by the developed software were compared with those by traditional finite element analysis. DC electrical outputs through rectifying circuitry were also examined for varying values of the smoothing capacitance and load resistance.

  20. A Control Scheme to Improve the Power Quality with the Absence of Dedicated Compensation Devices in Microgrid

    DEFF Research Database (Denmark)

    Naderipour, A.; Mohd Zin, A. A.; Habibuddin, M.H.

    2015-01-01

    devices, such as Active Power Filters (APFs). The proposed control method is composed of the Adjustable Synchronous Reference Frame (ASRF) and the Synchronous Reference Frame (SRF) methods. The ASRF and SRF are proposed to control the power injection and harmonic current compensation, respectively......In this paper, a new method is proposed to control the interface Inverter of distributed generators (DGs) in a microgrid. The objective of this method is to effectively compensate for the harmonic currents at the Point of Common Coupling (PCC) and the MG with the Absence of dedicated compensation....... The merged control methods are proposed for the interface inverter to perform the comprehensive activity of compensating for the harmonics, such as a correction of the system imbalance and the removal of the harmonics. The operation principle of the proposed control method is analyzed in detail, and its...