WorldWideScience

Sample records for neo-fuels discovery prospecting

  1. Beyond Discovery

    DEFF Research Database (Denmark)

    Korsgaard, Steffen; Sassmannshausen, Sean Patrick

    2017-01-01

    In this chapter we explore four alternatives to the dominant discovery view of entrepreneurship; the development view, the construction view, the evolutionary view, and the Neo-Austrian view. We outline the main critique points of the discovery presented in these four alternatives, as well...

  2. Prospective and comparative assessment of toxicity of adjuvant concomitant chemo-radiotherapy after neo-adjuvant chemotherapy in breast cancer; evaluation prospective et comparative de la toxicite de la chimioradiotherapie concomitante adjuvante apres chimiotherapie neoadjuvante dans le cancer du sein

    Energy Technology Data Exchange (ETDEWEB)

    Marchand, V.; Angelergues, A.; Gobaux, V.; Kirova, Y.M.; Campana, F.; Dendale, R.; Reyal, F.; Pierga, J.Y.; Fourquet, A.; Bollet, M.A. [Institut Curie, Paris (France)

    2011-10-15

    The authors report a prospective assessment of toxicity a treatment comprising an adjuvant chemo-radiotherapy after neo-adjuvant chemotherapy and a comparison with a treatment comprising only radiotherapy. Two sets of patients have been treated for a breast cancer between 1997 and 2002 by association of neo-adjuvant chemotherapy, surgery and radiotherapy with or without concomitant chemotherapy. Late toxicity has been assessed prospectively according to Common Terminology Criteria for Adverse Events. Acute toxicity has been noticed in medical files. The analysis of 142 treatments reveals that the concomitant administration of chemotherapy to radiotherapy after neo-adjuvant chemotherapy and surgery is associated with an increase of acute toxicity without increase of long term toxicity. Short communication

  3. Prospects for alternative Fusion Fuels

    International Nuclear Information System (INIS)

    Glancy, J.

    1986-01-01

    The author has worked on three different magnetic confinement concepts for alternate fusion fueled reactors: tokamaks; tanden mirrors, and reversed field pinches. The focus of this article is on prospects for alternate fusion fuels as the author sees them relative to the other choices: increased numbers of coal plants, fission reactors, renewables, and D-T fusion. Discussion is limited on the consideration of alternate fusion fuels to the catalyzed deuterium-deuterium fuel cycle. Reasons for seeking an alternate energy source are cost, a more secure fuel supply, environmental impact and safety. The technical risks associated with development of fusion are examined briefly

  4. An Empirical Analysis of the Price Discovery Function of Shanghai Fuel Oil Futures Market

    Institute of Scientific and Technical Information of China (English)

    Wang Zhen; Liu Zhenhai; Chen Chao

    2007-01-01

    This paper analyzes the role of price discovery of Shanghai fuel oil futures market by using methods, such as unit root test, co-integration test, error correction model, Granger causality test, impulse-response function and variance decomposition. The results showed that there exists a strong relationship between the spot price of Huangpu fuel oil spot market and the futures price of Shanghai fuel oil futures market. In addition, the Shanghai fuel oil futures market exhibits a highly effective price discovery function.

  5. Neo-oogenesis in mammals.

    Science.gov (United States)

    Porras-Gómez, Tania Janeth; Moreno-Mendoza, Norma

    2017-08-01

    Recently, the existence of a mechanism for neo-oogenesis in the ovaries of adult mammals has generated much controversy within reproductive biology. This mechanism, which proposes that the ovary has cells capable of renewing the follicular reserve, has been described for various species of mammals. The first evidence was found in prosimians and humans. However, these findings were not considered relevant because the predominant dogma for reproductive biology at the time was that of Zuckerman. This dogma states that female mammals are born with finite numbers of oocytes that decline throughout postnatal life. Currently, the concept of neo-oogenesis has gained momentum due to the discovery of cells with mitotic activity in adult ovaries of various mammalian species (mice, humans, rhesus monkeys, domestic animals such as pigs, and wild animals such as bats). Despite these reports, the concept of neo-oogenesis has not been widely accepted by the scientific community, generating much criticism and speculation about its accuracy because it has been impossible to reproduce some evidence. This controversy has led to the creation of two positions: one in favour of neo-oogenesis and the other against it. Various animal models have been used in support of both camps, including both classic laboratory animals and domestic and wild animals. The aim of this review is to critically present the current literature on the subject and to evaluate the arguments pro and contra neo-oogenesis in mammals.

  6. Neo-sex Chromosomes in the Monarch Butterfly, Danaus plexippus

    Directory of Open Access Journals (Sweden)

    Andrew J. Mongue

    2017-10-01

    Full Text Available We report the discovery of a neo-sex chromosome in the monarch butterfly, Danaus plexippus, and several of its close relatives. Z-linked scaffolds in the D. plexippus genome assembly were identified via sex-specific differences in Illumina sequencing coverage. Additionally, a majority of the D. plexippus genome assembly was assigned to chromosomes based on counts of one-to-one orthologs relative to the butterfly Melitaea cinxia (with replication using two other lepidopteran species, in which genome scaffolds have been mapped to linkage groups. Sequencing coverage-based assessments of Z linkage combined with homology-based chromosomal assignments provided strong evidence for a Z-autosome fusion in the Danaus lineage, involving the autosome homologous to chromosome 21 in M. cinxia. Coverage analysis also identified three notable assembly errors resulting in chimeric Z-autosome scaffolds. Cytogenetic analysis further revealed a large W chromosome that is partially euchromatic, consistent with being a neo-W chromosome. The discovery of a neo-Z and the provisional assignment of chromosome linkage for >90% of D. plexippus genes lays the foundation for novel insights concerning sex chromosome evolution in this female-heterogametic model species for functional and evolutionary genomics.

  7. Prospects for Australian involvement in the nuclear fuel cycle

    International Nuclear Information System (INIS)

    Chandra, S.; Hallenstein, C.

    1988-05-01

    A review of recent overseas developments in the nuclear industry by The Northern Territory Department of Mines and Energy suggests that there are market prospects in all stages of the fuel cycle. Australia could secure those markets through aggressive marketing and competitive prices. This report gives a profile of the nuclear fuel cycle and nuclear fuel cycle technologies, and describes the prospects of Australian involvement in the nuclear fuel cycle. It concludes that the nuclear fuel cycle industry has the potential to earn around $10 billion per year in export income. It recommend that the Federal Government: (1) re-examines its position on the Slayter recommendation (1984) that Australia should develop new uranium mines and further stages of the nuclear fuel cycle, and (2) gives it's in-principle agreement to the Northern Territory to seek expressions of interest from the nuclear industry for the establishment of an integrated nuclear fuel cycle industry in the Northern Territory

  8. Prospective thorium fuels for future nuclear energy generation

    International Nuclear Information System (INIS)

    Lainetti, Paulo E.O.

    2017-01-01

    In the beginning of the Nuclear Era, many countries were interested on thorium, particularly during the 1950 1970 periods. Nevertheless, since its discovery almost two centuries ago, the use of thorium has been restricted to gas mantles employed in gas lighting. The future world energy needs will increase and, even if we assumed a conservative contribution of nuclear generation, it will be occur a significant increasing in the uranium prices, taking into account that uranium, as used in the present thermal reactors, is a finite resource. Nowadays approximately the worldwide yearly requirement of uranium for about 435 nuclear reactors in operation is 65,000 metric t. Therefore, alternative solutions for future must be developed. Thorium is nearly three times more abundant than uranium in The Earth's crust. Despite thorium is not a fissile material, 232 Th can be converted to 233 U (fissile) more efficiently than 238 U to 239 Pu. Besides this, thorium is an environment alternative energy source and also inherently resistant to proliferation.. Many countries had initiated research on thorium in the past, Nevertheless, the interest evanesced due new uranium resources discoveries and availability of enriched uranium at low prices from obsolete weapons. Some papers evaluate the thorium resources in Brazil over 1.200.000 metric t. Then, the thorium alternative must be seriously considered in Brazil for strategic reasons. A brief history of thorium and its utilization are presented, besides a very short discussion about prospective thorium nuclear fuels for the next generation of nuclear reactors. (author)

  9. Prospective thorium fuels for future nuclear energy generation

    Energy Technology Data Exchange (ETDEWEB)

    Lainetti, Paulo E.O., E-mail: lainetti@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2017-07-01

    In the beginning of the Nuclear Era, many countries were interested on thorium, particularly during the 1950 1970 periods. Nevertheless, since its discovery almost two centuries ago, the use of thorium has been restricted to gas mantles employed in gas lighting. The future world energy needs will increase and, even if we assumed a conservative contribution of nuclear generation, it will be occur a significant increasing in the uranium prices, taking into account that uranium, as used in the present thermal reactors, is a finite resource. Nowadays approximately the worldwide yearly requirement of uranium for about 435 nuclear reactors in operation is 65,000 metric t. Therefore, alternative solutions for future must be developed. Thorium is nearly three times more abundant than uranium in The Earth's crust. Despite thorium is not a fissile material, {sup 232}Th can be converted to {sup 233}U (fissile) more efficiently than {sup 238}U to {sup 239}Pu. Besides this, thorium is an environment alternative energy source and also inherently resistant to proliferation.. Many countries had initiated research on thorium in the past, Nevertheless, the interest evanesced due new uranium resources discoveries and availability of enriched uranium at low prices from obsolete weapons. Some papers evaluate the thorium resources in Brazil over 1.200.000 metric t. Then, the thorium alternative must be seriously considered in Brazil for strategic reasons. A brief history of thorium and its utilization are presented, besides a very short discussion about prospective thorium nuclear fuels for the next generation of nuclear reactors. (author)

  10. NEOview: Near Earth Object Data Discovery and Query

    Science.gov (United States)

    Tibbetts, M.; Elvis, M.; Galache, J. L.; Harbo, P.; McDowell, J. C.; Rudenko, M.; Van Stone, D.; Zografou, P.

    2013-10-01

    Missions to Near Earth Objects (NEOs) figure prominently in NASA's Flexible Path approach to human space exploration. NEOs offer insight into both the origins of the Solar System and of life, as well as a source of materials for future missions. With NEOview scientists can locate NEO datasets, explore metadata provided by the archives, and query or combine disparate NEO datasets in the search for NEO candidates for exploration. NEOview is a software system that illustrates how standards-based interfaces facilitate NEO data discovery and research. NEOview software follows a client-server architecture. The server is a configurable implementation of the International Virtual Observatory Alliance (IVOA) Table Access Protocol (TAP), a general interface for tabular data access, that can be deployed as a front end to existing NEO datasets. The TAP client, seleste, is a graphical interface that provides intuitive means of discovering NEO providers, exploring dataset metadata to identify fields of interest, and constructing queries to retrieve or combine data. It features a powerful, graphical query builder capable of easing the user's introduction to table searches. Through science use cases, NEOview demonstrates how potential targets for NEO rendezvous could be identified by combining data from complementary sources. Through deployment and operations, it has been shown that the software components are data independent and configurable to many different data servers. As such, NEOview's TAP server and seleste TAP client can be used to create a seamless environment for data discovery and exploration for tabular data in any astronomical archive.

  11. The prospects for dry fuel storage

    International Nuclear Information System (INIS)

    Harris, G.G.; Elliott, D.

    1994-01-01

    Dry storage of spent nuclear fuels is one method of dealing with radioactive waste. This article reports from a one day seminar on future prospects for dry fuel storage held in November 1993. Dry storage in an inert gas or air environment in vaults or casks, is an alternative to wet storage in water-filled ponds. Both wet and dry storage form part of the Interim Storage option for radioactive waste materials, and form alternatives to reprocessing or direct disposal in a deep repository. It has become clear that a large market for dry fuel storage will exist in the future. It will therefore be necessary to ensure that the various technical, safety, commercial, legislative and political constraints associated with it can be met effectively. (UK)

  12. Cornell Fuel Cell Institute: Materials Discovery to Enable Fuel Cell Technologies

    Energy Technology Data Exchange (ETDEWEB)

    Abruna, H.D.; DiSalvo, Francis J.

    2012-06-29

    The discovery and understanding of new, improved materials to advance fuel cell technology are the objectives of the Cornell Fuel Cell Institute (CFCI) research program. CFCI was initially formed in 2003. This report highlights the accomplishments from 2006-2009. Many of the grand challenges in energy science and technology are based on the need for materials with greatly improved or even revolutionary properties and performance. This is certainly true for fuel cells, which have the promise of being highly efficient in the conversion of chemical energy to electrical energy. Fuel cells offer the possibility of efficiencies perhaps up to 90 % based on the free energy of reaction. Here, the challenges are clearly in the materials used to construct the heart of the fuel cell: the membrane electrode assembly (MEA). The MEA consists of two electrodes separated by an ionically conducting membrane. Each electrode is a nanocomposite of electronically conducting catalyst support, ionic conductor and open porosity, that together form three percolation networks that must connect to each catalyst nanoparticle; otherwise the catalyst is inactive. This report highlights the findings of the three years completing the CFCI funding, and incudes developments in materials for electrocatalyts, catalyst supports, materials with structured and functional porosity for electrodes, and novel electrolyte membranes. The report also discusses developments at understanding electrocatalytic mechanisms, especially on novel catalyst surfaces, plus in situ characterization techniques and contributions from theory. Much of the research of the CFCI continues within the Energy Materials Center at Cornell (emc2), a DOE funded, Office of Science Energy Frontier Research Center (EFRC).

  13. Deep Interior: Multiple-Rendezvous Prospecting of NEOs

    Science.gov (United States)

    Kakuda, R. Y.; Asphaug, E.; Belton, M. J. S.; Gulkis, S.; Huebner, W. F.

    2000-10-01

    This is an international multiple-rendezvous mission designed to prospect the deep interior and subsurface geophysical properties of diverse near-Earth objects, using reflection radar tomography, imaging, gravity, and explosions. What we learn will greatly influence future missions and guide strategies for the diversion, disruption, or utilization of potentially hazardous objects. Deep Interior. Low-frequency radar to determine internal variations of complex permittivity at resolutions approaching 20 m. Map inclusions or voids, fracture geometries, and compositional or structural boundaries. Subsurface. High-frequency radar to determine depth of regolith, existence and nature of cometary mantle, geology beneath and around craters, and subsurface expressions to surface geology. Topography and Geodesy. Stereogrammetric imaging with 1 m/pixel spatial resolution, supplemented by radar altimetry in shadowed regions, to determine detailed shape, volume, and spin state. Compare with radar sounding to learn how internal structure is manifested on the surface. Mass and Density. Total mass and lower moments of the internal mass distribution by mapping the exterior gravitational field. Look for mass concentrations. Surface microphysics and composition. Map color, albedo, and scattering properties of the surface over sunlit regions in six optical filters. Material properties. Deploy grenades to characterize the mechanics and dynamics of surface materials. Record 8 frame/sec, 20 cm/pixel videos of crater formation and ejecta dynamics, to enable simple and direct laboratory constraints on material density, cohesion and porosity. Dust. Look for dust lofted by surface waves propagating from the explosions, to constrain elastic properties and attenuation. Observe longer-term dynamics and optical properties of dust "atmosphere" generated by human activity. Cometary Activity. At comet 107P/Wilson-Harrington, look for expressions of past cometary activity, and for possible awakening

  14. An updated assessment of the prospects for fuel cell-powered buses. An information paper

    Energy Technology Data Exchange (ETDEWEB)

    Sanderson, T.K. [Future Energy Solutions, Harwell (United Kingdom)

    2005-07-01

    This report presents updated conclusions of the Department of Trade and Industry's research and development programme to assess the commercial prospects for advanced fuel cells in buses. The programme has focussed on low temperature solid polymer fuel cells (SPFCs) for transport and combined heat and power (CHP)/distributed power and high temperature solid oxide fuel cells (SOFCs) for CHP/distributed power. As well as assessing the prospects for SPFCs in buses, the report examines those for alkaline fuel cells (AFCs) and phosphoric acid fuel cells (PAFCs) in buses. The report provides an assessment of the status of technology development for different types of fuel cells in terms of applications to buses and offers estimates of market potential. Some fuel-cell powered buses are now available for demonstration purposes but the report concludes that truly commercial sales are unlikely to start before 2010 and widespread deployment is expected to take a further ten years after that. Buses have now slipped behind cars in terms of worldwide deployment. The issue of fuel choice is considered largely resolved with most fleet vehicle/bus manufacturers currently focussing on hydrogen as a fuel. A discussion of the prospects and barriers for fuel cell buses concludes that cost reduction is now the major barrier to the successful commercialisation of fuel cells in buses. More demonstration prototypes and field trials are required to provide information on energy, environmental and economic performance of fuel cell buses. Field trials could also provide information to assist the development of refuelling systems, fuel storage systems, stacks and other system components and to gain experience of building integrated fuel cell systems.

  15. TMAP: A NEO follow-up program utilizing undergraduate observers

    Science.gov (United States)

    Ramirez, C.; Deaver, D.; Martinez, R.; Foster, J.; Kuang, L.; Ates, A.; Anderson, M.; Mijac, M.; Gillam, S.; Hicks, M. D.

    2000-10-01

    In the spring of 2000 we began TMAP (Table Mountain Astrometry Project), a program designed to provide timely astrometric followup of newly discovered near-Earth asteroids. Relying on undergraduate observers from the local California State Universities, we have to date been involved with the over 50 NEO and new comet discoveries. This is a significant fraction of all near-Earth asteroids discovered over the time period. All observations are performed at JPL's Table Mountain Facility near Wrightwood California using the 0.6-meter telescope equipped with a Photometrics LN cooled 1k CCD mounted at the cassegrain focus. With this system we can routinely detect objects to R=20.5. We have typically scheduled two runs per month on weekends bracketing the new moon. The student observers man the telescope are trained to select and obtain R-band images of candidates from the Minor Planet Center's NEO Confirmation Page (http://cfa-www.harvard.edu/cfa/ps/NEO/TheNEOPage.html). The astrometry is then reduced and submitted to the Minor Planet Center the following day. TMAP has proven to be an efficient way both to obtain much needed astrometric measurements of newly discovered small bodies as well as to involve undergraduate researchers in planetary research. The limiting magnitudes provided by the 0.6-meter partially fills the gap between the extremely helpful and dedicated amateur astromitrists and the followup that the NEO detection programs do themselves. This work is supported by NASA.

  16. WWER fuel performance, development, QA and future prospects at Loviisa NPS

    Energy Technology Data Exchange (ETDEWEB)

    Loesoenen, P [Imatran Voima Oy, Vantaa (Finland)

    1994-12-31

    The essential characteristics of Loviisa fuel service are presented. A brief description is given of the steps in developing the performance values including: burnup dependent linear heat rate for fuel rods, comparison of measured and calculated cladding creep down of some rods, development of average discharge burnup for unit 1 and unit 2, results from experimental irradiation of test rods in research reactors. Some noticeable design changes performed and in-reactor behaviour of the lead fuel assemblies are also discussed. The quality assurance of the fuel procurement and operation is explained. Future prospects are connected with power raise of Loviisa reactors, discontinuing of spent fuel transportation to Russia for final disposal and new WWER fuel deliverers. 4 figs., 1 tab., 8 refs.

  17. Resumption of pulsing the NSCR following the discovery of damaged fuel

    International Nuclear Information System (INIS)

    Feltz, D.E.; Rogers, R.D.

    1984-01-01

    Pulsing operations of the Nuclear Science Center Reactor (NSCR) at Texas A and M University were terminated in 1976 following the discovery of three damaged fuel elements during a routine inspection. A commitment was then made to the U.S. Nuclear Regulatory Commission to terminate pulsing of the NSCR until a thorough study of the damaged fuel had been completed. A report describing that study and discussing the possible mechanism of damage was issued in 1981. Based on a recommendation in the report to establish a limiting temperature to protect against damage, the USNRC issued a letter authorizing the reinitiation of pulsing the NSCR but limiting pulsing parameters 'to those in the current technical specifications or to a maximum calculated fuel temperature of 830 deg. C. It is felt based on the data obtained and fuel inspection results that the requirements of Phase I and Phase III of the Pulse Test Program for Core VIII have been met. Phase II of the test program will not be implemented unless there is a requirement for higher pulse energy and flux. The reproducibility of pulse data was very satisfactory

  18. Prospects for early discoveries at the LHC with dileptons, jets and no missing energy

    International Nuclear Information System (INIS)

    Ciaccio, A. di; Thompson, E.

    2009-01-01

    Final states with high p T leptons and jets, without missing energy, are predicted by several BSM models at the LHC, including LR symmetric models and Leptoquarks. The prospects for an early discovery of particles predicted by these models, using the ATLAS experiment, are discussed. These particles include in particular first and second generation leptoquarks, right-handed W and heavy neutrinos. (author)

  19. An updated assessment of the prospects for fuel cell-powered cars. An information paper

    Energy Technology Data Exchange (ETDEWEB)

    Sanderson, T.K. [Future Energy Solutions, Harwell (United Kingdom)

    2005-07-01

    This report presents updated conclusions of the Department of Trade and Industry's research and development programme to assess the commercial prospects for advanced fuel cells in the car market. The programme has focussed on low temperature solid polymer fuel cells (SPFCs) for transport and combined heat and power (CHP)/distributed power and high temperature solid oxide fuel cells (SOFCs) for CHP/distributed power. The report provides an assessment of the status of technology development for different types of fuel cells in terms of applications to cars and offers estimates of market potential. Some fuel-cell powered cars are now available for demonstration purposes but the report concludes that truly commercial sales are unlikely to start before 2010 and widespread deployment is expected to take a further ten years after that. The issue of fuel choice is considered largely resolved with most car manufacturers currently focussing on hydrogen as a fuel. A discussion of the prospects and barriers for fuel cell cars concludes that cost reduction is now the major barrier to the successful commercialisation of fuel cells in cars. More demonstration prototypes and field trials are required to provide information on energy, environmental and economic performance of fuel cell cars. Field trials could also provide information to assist the development of refuelling systems, fuel storage systems, stacks and other system components and to gain experience of building integrated fuel cell systems within the constraints imposed by cars.

  20. [Progress and prospect of bio-jet fuels industry in domestic and overseas].

    Science.gov (United States)

    Qiao, Kai; Fu, Jie; Zhou, Feng; Ma, Huixia

    2016-10-25

    We reviewed the progress of the bio-jet fuels industry in recent years and systematically analyzed the technical routes that have been approved or in the pipeline for approval by ASTM D7566. In addition, we highlighted a novel pathway to produce drop-in fuel by near-critical hydrolysis of waste cooking oils or algal oils followed by catalytic decarboxylation. Also, we introduced the source of oils and fats feedstock and the domestic bio-jet fuel industry status during the 12th Five-Year-Plan period. Based on our own research, we discussed the prospect of the bio-jet fuel industry and future research needs.

  1. Status and prospects for spent fuel management in France

    International Nuclear Information System (INIS)

    Kaplan, P.

    1998-01-01

    The 70's oil crisis has shown that the energy resource dependence of France was too high. The decision was made by the French government to accelerate the implementation of an ambitious nuclear power programme, based on Light Water Reactors, and to do the utmost to reuse the energy bearing material included in the spent fuel. The French nuclear policy has not changed since then. This paper is aimed at describing the present status of implementation of this policy, and the associated prospects. It will first sum up the presentation made in 1995 to the Regular Advisory Group of IAEA on Spent Fuel Management. Then, it will update the situation of the main actors of the spent fuel management policy in France: EDF, the national utility; COGEMA, world leader on almost all the steps of the fuel cycle; CEA, the national research body in the field of nuclear science and its applications; ANDRA, national body in charge of the management of the waste arising from the nuclear activities in France, final disposal included. (author)

  2. Present status and future prospects for a Higgs boson discovery at the Tevatron and LHC

    International Nuclear Information System (INIS)

    Haber, Howard E

    2010-01-01

    Discovering the Higgs boson is one of the primary goals of both the Tevatron and the Large Hadron Collider (LHC). The present status of the Higgs search is reviewed and future prospects for discovery at the Tevatron and LHC are considered. This talk focuses primarily on the Higgs boson of the Standard Model and its minimal supersymmetric extension. Theoretical expectations for the Higgs boson and its phenomenological consequences are reviewed.

  3. Carbon dioxide emissions from fossil fuel use: Recent performance and future prospects

    Energy Technology Data Exchange (ETDEWEB)

    Jefferson, Michael

    1998-12-01

    This publication gives an overview and discusses carbon dioxide emissions from fossil fuel use worldwide. Main themes discussed in this connection cover recent performance and future prospects. Some proposals on the reduction of CO{sub 2} emissions are given

  4. Neo-Babylonian Laundry

    NARCIS (Netherlands)

    Waerzeggers, C.A.H.

    2006-01-01

    The clothes of the gods were regularly washed by specialized craftsmen in Neo-Babylonian temples (Bongenaar 1997: 304ff.), but who did the laundry of ordinary people? It is symptomatic of the character of Neo-Babylonian documentation that a simple question like this one is difficult to answer: while

  5. Neo4j cookbook

    CERN Document Server

    Goel, Ankur

    2015-01-01

    If you are already using Neo4j in your application and want to learn more about data analysis or database graphs, this is the book for you. This book also caters for your needs if you are looking to migrate your existing application to Neo4j in the future. We assume that you are already familiar with any general purpose programming language and have some familiarity with Neo4j.

  6. An updated assessment of the prospects for fuel cells in stationary power and CHP. An information paper

    Energy Technology Data Exchange (ETDEWEB)

    Sanderson, T.K. [Future Energy Solutions, Harwell (United Kingdom)

    2005-07-01

    This report presents updated conclusions of the Department of Trade and Industry's research and development programme to assess the commercial prospects for advanced fuel cells in stationary power and combined heat and power (CHP) systems. The programme has focussed on low temperature solid polymer fuel cells (SPFCs) for transport and combined heat and power (CHP)/distributed power and high temperature solid oxide fuel cells (SOFCs) for CHP/distributed power. As well as assessing the prospects for SPFCs and SOFCs in stationary power and CHP applications, the report examines those for molten carbonate fuel cells (MCFCs) and phosphoric acid fuel cells (PAFCs). The report provides an assessment of the status of technology development for these different types of fuel cells in terms of applications to stationary power and CHP, and offers estimates of market potential for SOFCs in CHP markets, SPFCs in CHP markets and SOFCs in distributed power generation markets. Both large SPFC and SOFC CHP systems require further development to deliver the necessary cost reductions in materials and manufacturing processes before pre-commercial sales can begin. The routes taken by different manufacturers and their choice of preferred technology are explained. A discussion of the prospects and barriers for fuel cell cars concludes that while cost reduction is a major barrier to the successful commercialisation of fuel cells, there are insufficient data available from operating fuel cells systems (other than PAFC) in stationary power and CHP applications to assess the economic attractiveness of fuel cells compared with existing systems. More field trials are required to confirm energy and environmental performance in such applications and to evaluate operational and economic performance under commercial operating conditions. Such field trials could also provide a focus for the required developments in fuel cells for stationary power/CHP systems.

  7. Contemporary and prospective fuel cycles for WWER-440 based on new assemblies with higher uranium capacity and higher average fuel enrichment

    International Nuclear Information System (INIS)

    Gagarinskiy, A.A.; Saprykin, V.V.

    2009-01-01

    RRC 'Kurchatov Institute' has performed an extensive cycle of calculations intended to validate the opportunities of improving different fuel cycles for WWER-440 reactors. Works were performed to upgrade and improve WWER-440 fuel cycles on the basis of second-generation fuel assemblies allowing core thermal power to be uprated to 107 108 % of its nominal value (1375 MW), while maintaining the same fuel operation lifetime. Currently intensive work is underway to develop fuel cycles based on second-generation assemblies with higher fuel capacity and average fuel enrichment per assembly increased up to 4.87 % of U-235. Fuel capacity of second-generation assemblies was increased by means of eliminated central apertures of fuel pellets, and pellet diameter extended due to reduced fuel cladding thickness. This paper intends to summarize the results of works performed in the field of WWER-440 fuel cycle modernization, and to present yet unemployed opportunities and prospects of further improvement of WWER-440 neutronic and operating parameters by means of additional optimization of fuel assembly designs and fuel element arrangements applied. (Authors)

  8. Depression related to (neo)adjuvant hormonal therapy for prostate cancer

    International Nuclear Information System (INIS)

    Tol-Geerdink, Julia J. van; Leer, Jan Willem; Lin, Emile N.J.T. van; Schimmel, Erik C.; Stalmeier, Peep F.M.

    2011-01-01

    Background: We studied whether hormonal therapy, (neo)adjuvant to radiotherapy for localized prostate cancer, is related to an increase in depression and whether this is caused by the hormonal therapy itself or by the relatively poor prognosis of patients who get (neo)adjuvant hormonal therapy. Methods: Between 2002 and 2005, 288 patients, irradiated for prostate cancer (T1-3N0M0), were studied prospectively in two clinics. In one clinic almost all patients received (neo)adjuvant androgen deprivation (Bicalutamide + Gosereline). In a second clinic hormonal therapy was prescribed mainly for high risk patients. This allowed us to separate the effects of hormonal therapy and the patient's prognosis. Results: During the course of hormonal therapy, depression was significantly heightened by both hormone use (p < 0.001) and poor prognosis (p < 0.01). After completion of hormonal therapy, poor prognosis continued to affect the depression score (p < 0.01). The increase was, however, small. Conclusions: Depression was mildly increased in patients receiving hormonal therapy. The increase appeared to be related to both the hormone therapy itself and the high risk status of patients. High risk status, with the associated poor prognosis, had a more sustained effect on depression. The rise was statistically significant, but was too small, however, to bear clinical significance.

  9. Selective extraction of metals from acidic uranium(VI) solutions using neo-tridecano-hydroxamic acid

    International Nuclear Information System (INIS)

    Bardoncelli, F.; Grossi, G.

    1975-01-01

    According to this invention neo-alkyl-hydroxamic acids are employed as ion-exchanging agents in processes for liquid-liquid extraction with the aim of separating, purifying dissolved metals and of converting a metal salt solution into a solution of a salt of the same metal but with different anion. In particular it is an objective of this invention to provide a method whereby a molecular pure uranium solution is obtained by selective extraction from a uranium solution delivered by irradiated fuel reprocessing plants and containing plutonium, fission products and other unwanted metals, in which method neo-tridecane-hydroxamic acid is employed as ion exchanger. (Official Gazette)

  10. Asteroids - NeoWs API

    Data.gov (United States)

    National Aeronautics and Space Administration — NeoWs (Near Earth Object Web Service) is a RESTful web service for near earth Asteroid information. With NeoWs a user can: search for Asteroids based on their...

  11. High-throughput characterization for solar fuels materials discovery

    Science.gov (United States)

    Mitrovic, Slobodan; Becerra, Natalie; Cornell, Earl; Guevarra, Dan; Haber, Joel; Jin, Jian; Jones, Ryan; Kan, Kevin; Marcin, Martin; Newhouse, Paul; Soedarmadji, Edwin; Suram, Santosh; Xiang, Chengxiang; Gregoire, John; High-Throughput Experimentation Team

    2014-03-01

    In this talk I will present the status of the High-Throughput Experimentation (HTE) project of the Joint Center for Artificial Photosynthesis (JCAP). JCAP is an Energy Innovation Hub of the U.S. Department of Energy with a mandate to deliver a solar fuel generator based on an integrated photoelectrochemical cell (PEC). However, efficient and commercially viable catalysts or light absorbers for the PEC do not exist. The mission of HTE is to provide the accelerated discovery through combinatorial synthesis and rapid screening of material properties. The HTE pipeline also features high-throughput material characterization using x-ray diffraction and x-ray photoemission spectroscopy (XPS). In this talk I present the currently operating pipeline and focus on our combinatorial XPS efforts to build the largest free database of spectra from mixed-metal oxides, nitrides, sulfides and alloys. This work was performed at Joint Center for Artificial Photosynthesis, a DOE Energy Innovation Hub, supported through the Office of Science of the U.S. Department of Energy under Award No. DE-SC0004993.

  12. Assessing the Universal Structure of Personality in Early Adolescence: The NEO-PI-R and NEO-PI-3 in 24 Cultures

    Science.gov (United States)

    De Fruyt, Filip; De Bolle, Marleen; McCrae, Robert R.; Terracciano, Antonio; Costa, Paul T., Jr.

    2009-01-01

    The structure and psychometric characteristics of the NEO Personality Inventory-3 (NEO-PI-3), a more readable version of the Revised NEO Personality Inventory (NEO-PI-R), are examined and compared with NEO-PI-R characteristics using data from college student observer ratings of 5,109 adolescents aged 12 to 17 years from 24 cultures. Replacement…

  13. Internationalization of the back end of the nuclear fuel cycle: Problems and prospects

    International Nuclear Information System (INIS)

    Haeckel, E.

    1997-01-01

    International cooperation and transnational division of labour is a distinctive feature of the nuclear industry, but it is conspicuously lacking at the back end of the nuclear fuel cycle. Meanwhile, national efforts to close the fuel cycle have remained largely unsuccessful. Governments and the nuclear industry are paralyzed in a gridlock of indecision and obstruction. This pattern has been reinforced at the international level. More recently, however, a number of dynamic challenges to governments and the industry has opened up new prospects for internationalization. (author)

  14. Internationalization of the back end of the nuclear fuel cycle: Problems and prospects

    Energy Technology Data Exchange (ETDEWEB)

    Haeckel, E [Forschunginstitut der Deutschen Gesellschaft fuer Auswaertige Politik, Bonn (Germany)

    1997-12-01

    International cooperation and transnational division of labour is a distinctive feature of the nuclear industry, but it is conspicuously lacking at the back end of the nuclear fuel cycle. Meanwhile, national efforts to close the fuel cycle have remained largely unsuccessful. Governments and the nuclear industry are paralyzed in a gridlock of indecision and obstruction. This pattern has been reinforced at the international level. More recently, however, a number of dynamic challenges to governments and the industry has opened up new prospects for internationalization. (author). 3 refs.

  15. On NEO Threat Mitigation (Preprint)

    Science.gov (United States)

    2007-10-15

    Yucatan event is at least a major contributor, if not the direct cause of the extinction of the dinosaurs . Moreover, it is clear that NEO impacts can... extinction of the human race. The probability of these events decreases with the severity of the impact, and size (mass) of the NEO. Figure 1 and Table 1...thus, it is more reasonable to infer that all the large NEOs can be catalogued within a reasonable time, while smaller and less consequential

  16. Is drug-induced toxicity a good predictor of response to neo-adjuvant chemotherapy in patients with breast cancer? -A prospective clinical study

    International Nuclear Information System (INIS)

    Chintamani; Singhal, Vinay; Singh, JP; Lyall, Ashima; Saxena, Sunita; Bansal, Anju

    2004-01-01

    Neo-adjuvant chemotherapy is an integral part of multi-modality approach in the management of locally advanced breast cancer and it is vital to predict the response in order to tailor the regime for a patient. The common final pathway in the tumor cell death is believed to be apoptosis or programmed cell death and chemotherapeutic drugs like other DNA-damaging agents act on rapidly multiplying cells including both the tumor and the normal cells by following the same common final pathway. This could account for both the toxic effects and the response. Absence or decreased apoptosis has been found to be associated with chemo resistance. The change in expression of apoptotic markers (Bcl-2 and Bax proteins) brought about by various chemotherapeutic regimens is being used to identify drug resistance in the tumor cells. A prospective clinical study was conducted to assess whether chemotherapy induced toxic effects could serve as reliable predictors of apoptosis or response to neo-adjuvant chemotherapy in patients with locally advanced breast cancer. 50 cases of locally advanced breast cancer after complete routine and metastatic work up were subjected to trucut biopsy and the tissue evaluated immunohistochemically for apoptotic markers (bcl-2/bax ratio). Three cycles of Neoadjuvant Chemotherapy using FAC regime (5-fluorouracil, adriamycin, cyclophosphamide) were given at three weekly intervals and patients assessed for clinical response as well as toxicity after each cycle. Modified radical mastectomy was performed in all patients three weeks after the last cycle and the specimen were re-evaluated for any change in the bcl-2/bax ratio. The clinical response, immunohistochemical response and the drug-induced toxicity were correlated and compared. Descriptive studies were performed with SPSS version 10 and the significance of response was assessed using paired t-test. Significance of correlation between various variables was assessed using chi-square test and coefficient

  17. Spent fuel management: Current status and prospects 1995. Proceedings of a regular advisory group meeting

    International Nuclear Information System (INIS)

    1996-08-01

    Spent fuel management has always been one of the important stages in the nuclear fuel cycle and it is still one of the most vital problems common to all countries with nuclear reactors. It begins with the discharge of spent fuel from a power or a research reactor and ends with its ultimate disposition, either by direct disposal or by reprocessing of the spent fuel. Two options exist - an open, once-through cycle with direct disposal of the spent fuel and a closed cycle with reprocessing of the spent fuel and recycling of plutonium and uranium in new mixed oxide fuels. The selection of a spent fuel strategy is a complex procedure in which many factors have to be weighed, including political, economic and safeguards issues as well as protection of the environment. This report gives an overview of the status of spent fuel management programmes in a number of countries, a description of the current status and prospects of activities in this field and recommendations of the participants. Refs, figs, tabs

  18. The Near Earth Object (NEO) Scout Spacecraft: A Low-cost Approach to In-situ Characterization of the NEO Population

    Science.gov (United States)

    Woeppel, Eric A.; Balsamo, James M.; Fischer, Karl J.; East, Matthew J.; Styborski, Jeremy A.; Roche, Christopher A.; Ott, Mackenzie D.; Scorza, Matthew J.; Doherty, Christopher D.; Trovato, Andrew J.; hide

    2014-01-01

    This paper describes a microsatellite spacecraft with supporting mission profile and architecture, designed to enable preliminary in-situ characterization of a significant number of Near Earth Objects (NEOs) at reasonably low cost. The spacecraft will be referred to as the NEO-Scout. NEO-Scout spacecraft are to be placed in Geosynchronous Equatorial Orbit (GEO), cis-lunar space, or on earth escape trajectories as secondary payloads on launch vehicles headed for GEO or beyond, and will begin their mission after deployment from the launcher. A distinguishing key feature of the NEO-Scout system is to design the spacecraft and mission timeline so as to enable rendezvous with and landing on the target NEO during NEO close approach (the Earth-Moon system using low-thrust/high-impulse propulsion systems. Mission durations are on the order 100 to 400 days. Mission feasibility and preliminary design analysis are presented, along with detailed trajectory calculations.

  19. Discussion of evolution between neo-lamarckism and neo-darwinism in the Czech lands, 1900-1915

    Czech Academy of Sciences Publication Activity Database

    Hermann, Tomáš; Šimůnek, Michal V.

    2010-01-01

    Roč. 32, č. 3 (2010), s. 283-300 ISSN 1210-0250 R&D Projects: GA ČR GPP410/10/P550 Institutional research plan: CEZ:AV0Z80630520 Keywords : neo-lamarckism * neo- darwinism * history of biology Subject RIV: AB - History

  20. Recent advances in fuel fabrication techniques and prospects for the nineties

    International Nuclear Information System (INIS)

    Frain, R.G.; Caudill, H.L.; Faulhaber, R.

    1987-01-01

    Advanced Nuclear Fuels Corporation's approach and experience with the application of a flexible, just-in-time manufacturing philosophy to the production of customized nuclear fuel is described. Automation approaches to improve productivity are described. The transfer of technology across product lines is discussed as well as the challenges presented by a multiple product fabrication facility which produces a wide variety of BWR and PWR designs. This paper also describes the method of managing vendor quality control programs in support of standardization and clarity of documentation. Process simplification and the ensuing experience are discussed. Prospects for fabrication process advancements in the nineties are given with emphasis on the benefits of dry conversion of UF 6 to UO 2 powder, and increased use of automated and computerized inspection techniques. (author)

  1. NEOS Server 4.0 Administrative Guide

    OpenAIRE

    Dolan, Elizabeth D.

    2001-01-01

    The NEOS Server 4.0 provides a general Internet-based client/server as a link between users and software applications. The administrative guide covers the fundamental principals behind the operation of the NEOS Server, installation and trouble-shooting of the Server software, and implementation details of potential interest to a NEOS Server administrator. The guide also discusses making new software applications available through the Server, including areas of concern to remote solver adminis...

  2. (Anti-Biography and Neo-Impressionism

    Directory of Open Access Journals (Sweden)

    Foa, Michelle

    2012-07-01

    Full Text Available This article analyzes neo-impressionism in relation to the biographical model of art criticism and art history that became increasingly prevalent in France over the course of the 19th century. Examining the critical response to the neo-impressionists, as well as some of their pictures and writings, I argue for the centrality of questions of authorship, individuality, and subjectivity to the group and its reception. I identify a distinctly anti-biographical tendency in the movement, one that disquieted the critics and led them to try and re-inscribe biographical meaning back into the work of Georges Seurat. Indeed, though Seurat instituted a divide between his work and his life in a variety of ways, he also insisted throughout his career on his paternity over the neo-impressionist method. In all of these ways, the relationship between the self and art was a significant and problematic issue for the neo-impressionists and the critics around them.

  3. Storage of Spent Nuclear Fuel in Norway: Status and Prospects

    International Nuclear Information System (INIS)

    Bennett, Peter; Larsen, Erlend

    2014-01-01

    Spent Nuclear Fuel (SNF) in Norway has arisen from irradiation of fuel in the JEEP I and JEEP II reactors at Kjeller, and in the Halden Boiling Water Reactor (HBWR) in Halden. In total there are some 16 tonnes of SNF, all of which is currently stored on-site, in either wet or dry storage facilities. The greater part of the SNF, 12 tonnes, consists of aluminium-clad fuel, of which 10 tonnes is metallic uranium fuel and the remainder oxide (UO 2 ). Such fuel presents significant challenges with respect to long-term storage and disposal. Current policy is that existing spent fuel will, as far as possible considering its suitability for later direct disposal, be stored until final disposal is possible. Several committees have advised the Government of Norway on, among others, policy issues, storage methods and localisation of a storage facility. Both experts and stakeholders have participated in these committees. This paper presents an overview of the spent fuel in Norway and a description of current storage arrangements. The prospects for long-term storage are then described, including a summary of recommendations made to government, the reactions of various stakeholders to these recommendations, the current status, and the proposed next steps. A recommended policy is to construct a new storage facility for the fuel to be stored for a period of at least 50 years. In the meantime a national final disposal facility should be constructed and taken into operation. It has been recommended that the aluminium-clad fuel be reprocessed in an overseas commercial facility to produce a stable waste form for storage and disposal. This recommendation is controversial, and a decision has not yet been taken on whether to pursue this option. An analysis of available storage concepts for the more modern fuel types resulted in the recommendation to use dual-purpose casks. In addition, it was recommended to construct a future storage facility in a rock hall instead of a free

  4. Project NEO Specific Impulse Testing Solutions

    Science.gov (United States)

    Baffa, Bill

    2018-01-01

    The Neo test stand is currently configured to fire a horizontally mounted rocket motor with up to 6500 lbf thrust. Currently, the Neo test stand can measure flow of liquid propellant and oxidizer, pressures residing in the closed system up to the combustion chamber. The current configuration does not have the ability to provide all data needed to compute specific impulse. This presents three methods to outfit the NEO test fixture with instrumentation allowing for calculation of specific impulse.

  5. The Economics OF NEOS

    Science.gov (United States)

    Schalkwyk, James D.

    2014-01-01

    NASA's Ames Research Center, in its role as partnerships lead for NASA asteroid redirect robotic missions and as a supporting Center for the Asteroid Grand Challenge, responded to increasing interest in near-Earth objects (NEOs) by holding a workshop entitled 'The Economics of NEOs' on the 6th and 7th of September 2014. The workshop was intended to serve as a catalyst for discussions and to foster collaborations between industry, academia and government. This document serves as a summary of the discussions which took place within three sessions and their respective table discussions; Session One: Background and Motivation; Session Two: Economics of NEOs; and Session Three: Policy and Legal Frameworks. This document is a collection of observations by individuals and does not express the consensus view of all participants; it does not express US Government or NASA policy.

  6. The Old Neo-Liberalism. The Neo-Liberalist Germ in Mises' and Hayek's Theories

    Directory of Open Access Journals (Sweden)

    Vanessa Lamattina

    2016-09-01

    Full Text Available What is neo-liberalism? I’m going to affirm here that, as well as being a political doctrine born in the 1970s, neo-liberalism is the construction, the extension and the final reinforcement of a number of classical elements. My argument is that many of the typical aspects of contemporary neo-liberalism were already present in theories expressed by thinkers such as L. von Mises and F. A. von Hayek. As proof of this fact, I reclaim some characteristics of the present neo-liberal phenomenon as having been conceived by the above authors. These characteristics actually imply the ongoing spread of a dominant ideology that tends to pit the concept of liberty against those of rationality and critical consciousness. First, the article will analyse the changes that have occurred within the phenomenon of consumerism, which becomes en-twined with the competitive and entrepreneurial spirit of the individual; second, it will reflect on the wide-spread aversion to socialist policies, and in fact to all policies that provide for public intervention by the State and that change the relationship between State and economy; finally, it will relate these investiga-tions to the ideological and structural model that supports the European Union.

  7. Is drug-induced toxicity a good predictor of response to neo-adjuvant chemotherapy in patients with breast cancer? -A prospective clinical study

    Directory of Open Access Journals (Sweden)

    Singh JP

    2004-08-01

    Full Text Available Abstract Background Neo-adjuvant chemotherapy is an integral part of multi-modality approach in the management of locally advanced breast cancer and it is vital to predict the response in order to tailor the regime for a patient. The common final pathway in the tumor cell death is believed to be apoptosis or programmed cell death and chemotherapeutic drugs like other DNA-damaging agents act on rapidly multiplying cells including both the tumor and the normal cells by following the same common final pathway. This could account for both the toxic effects and the response. Absence or decreased apoptosis has been found to be associated with chemo resistance. The change in expression of apoptotic markers (Bcl-2 and Bax proteins brought about by various chemotherapeutic regimens is being used to identify drug resistance in the tumor cells. A prospective clinical study was conducted to assess whether chemotherapy induced toxic effects could serve as reliable predictors of apoptosis or response to neo-adjuvant chemotherapy in patients with locally advanced breast cancer. Methods 50 cases of locally advanced breast cancer after complete routine and metastatic work up were subjected to trucut biopsy and the tissue evaluated immunohistochemically for apoptotic markers (bcl-2/bax ratio. Three cycles of Neoadjuvant Chemotherapy using FAC regime (5-fluorouracil, adriamycin, cyclophosphamide were given at three weekly intervals and patients assessed for clinical response as well as toxicity after each cycle. Modified radical mastectomy was performed in all patients three weeks after the last cycle and the specimen were re-evaluated for any change in the bcl-2/bax ratio. The clinical response, immunohistochemical response and the drug-induced toxicity were correlated and compared. Descriptive studies were performed with SPSS version 10 and the significance of response was assessed using paired t-test. Significance of correlation between various variables was

  8. Patterns of molecular evolution of an avian neo-sex chromosome.

    Science.gov (United States)

    Pala, Irene; Hasselquist, Dennis; Bensch, Staffan; Hansson, Bengt

    2012-12-01

    Newer parts of sex chromosomes, neo-sex chromosomes, offer unique possibilities for studying gene degeneration and sequence evolution in response to loss of recombination and population size decrease. We have recently described a neo-sex chromosome system in Sylvioidea passerines that has resulted from a fusion between the first half (10 Mb) of chromosome 4a and the ancestral sex chromosomes. In this study, we report the results of molecular analyses of neo-Z and neo-W gametologs and intronic parts of neo-Z and autosomal genes on the second half of chromosome 4a in three species within different Sylvioidea lineages (Acrocephalidea, Timaliidae, and Alaudidae). In line with hypotheses of neo-sex chromosome evolution, we observe 1) lower genetic diversity of neo-Z genes compared with autosomal genes, 2) moderate synonymous and weak nonsynonymous sequence divergence between neo-Z and neo-W gametologs, and 3) lower GC content on neo-W than neo-Z gametologs. Phylogenetic reconstruction of eight neo-Z and neo-W gametologs suggests that recombination continued after the split of Alaudidae from the rest of the Sylvioidea lineages (i.e., after ~42.2 Ma) and with some exceptions also after the split of Acrocephalidea and Timaliidae (i.e., after ~39.4 Ma). The Sylvioidea neo-sex chromosome shares classical evolutionary features with the ancestral sex chromosomes but, as expected from its more recent origin, shows weaker divergence between gametologs.

  9. AquaLase versus NeoSoniX--a comparison study.

    Science.gov (United States)

    Jiraskova, Nada; Rozsival, Pavel; Kadlecova, Jana; Nekolova, Jana; Pozlerova, Jana; Dubravska, Zlatica

    2007-12-01

    To compare the metrics and surgical outcome when using Infiniti AquaLase and NeoSoniX cataract removal modalities. This prospective clinical study involved 50 patients with bilateral cataracts and lens removal using AquaLase in the right eye and NeoSoniX in the left eye. Best corrected visual acuity (BCVA), endothelial cell density and pachymetry were evaluted pre- and postoperatively. Statistical analysis was performed using the Wilcoxon Signed- Rank Test. Preoperative mean pachymetry was 569 +/- 31 mu in the right eye (RE) and 560 +/- 37 mu in the left eye (LE), mean endothelial cell density 2744 +/- 418 cells/mm(2) (RE) and 2730 +/- 472 cells/mm(2) (LE). One week after operation pachymetry was 576 +/- 52 mu (RE) and 583 +/- 72 mu (LE) and endothelial cell density 2388 +/- 586 cells/mm(2) (RE) and 2463 +/- 615 cells/mm(2) (LE). One month after surgery pachymetry was 556 +/- 43 mu (RE) and 559 +/- 44 mu (LE) and endothelial cell density 2368 +/- 52 cells/mm(2) (RE) and 2495 +/- 548 cells/mm(2) (LE). BCVA improved in all eyes and was 0.8 or better on the first postoperative day. Both the NeosoniX and AquaLase minimize intraoperative damage to ocular structures.

  10. The Large Synoptic Survey Telescope as a Near-Earth Object discovery machine

    Science.gov (United States)

    Jones, R. Lynne; Slater, Colin T.; Moeyens, Joachim; Allen, Lori; Axelrod, Tim; Cook, Kem; Ivezić, Željko; Jurić, Mario; Myers, Jonathan; Petry, Catherine E.

    2018-03-01

    Using the most recent prototypes, design, and as-built system information, we test and quantify the capability of the Large Synoptic Survey Telescope (LSST) to discover Potentially Hazardous Asteroids (PHAs) and Near-Earth Objects (NEOs). We empirically estimate an expected upper limit to the false detection rate in LSST image differencing, using measurements on DECam data and prototype LSST software and find it to be about 450 deg-2. We show that this rate is already tractable with current prototype of the LSST Moving Object Processing System (MOPS) by processing a 30-day simulation consistent with measured false detection rates. We proceed to evaluate the performance of the LSST baseline survey strategy for PHAs and NEOs using a high-fidelity simulated survey pointing history. We find that LSST alone, using its baseline survey strategy, will detect 66% of the PHA and 61% of the NEO population objects brighter than H = 22 , with the uncertainty in the estimate of ± 5 percentage points. By generating and examining variations on the baseline survey strategy, we show it is possible to further improve the discovery yields. In particular, we find that extending the LSST survey by two additional years and doubling the MOPS search window increases the completeness for PHAs to 86% (including those discovered by contemporaneous surveys) without jeopardizing other LSST science goals (77% for NEOs). This equates to reducing the undiscovered population of PHAs by additional 26% (15% for NEOs), relative to the baseline survey.

  11. Discovery of fuel cell anode electrocatalysts and dehydrogenation catalysts using combinatorial techniques

    Science.gov (United States)

    Chan, Benny Chun Wai

    A gas diffusion optical screening method was developed for the discovery of catalysts for the electro-oxidation of reformate gas (H2 with 100 ppm CO). The screening cell was designed to accommodate a gas diffusion layer, 715 member catalyst array, and an electrolyte container. Since protons are generated during H2 oxidation, a pH sensitive fluorphore was used to identify active compositions. The cell showed no detectable iR drop across the array and ranked activity of two commercial PtRu and one Pt catalysts. Over 95% of a given catalyst fluoresced at the initial onset potential and a 5 mV difference in onset potential of two different catalysts was statistically different. A gas diffusion half cell was designed similar to the optical screening cell to obtain current-potential curves of bulk catalysts. The screening results correlated with half cell and fuel cell data, internally validating the method. The combinatorial method was then applied to search for catalysts in the PtRuMoIrRh composition space. The catalysts on the array were prepared by hydrogen reduction of the metals salts on carbon. The most active catalysts were from the Pt enriched regions of the PtRuMoRh quaternary. Bulk catalysts were prepared from the active regions and tested in the gas diffusion half cell. The most active catalysts in the optical screening were also the most active catalysts in the half cell. When any homemade catalysts were compared to commercial PtRu, however, the performance was worse. A high surface area, high catalyst activity synthetic method is the most important factor to reliably screen catalysts for "real world" fuel cell application. High surface area catalysts were tested for direct methanol oxidation activity. The optical screening method was compared with disk electrode, high throughput fuel cell testing, and fuel cell testing. Six catalysts examined included two commercial PtRu catalysts, a Pt catalyst, and three homemade PtRu catalysts of varying activity

  12. Multiple NEO Rendezvous Using Solar Sails

    Science.gov (United States)

    Johnson, Les; Alexander, Leslie; Fabisinski, Leo; Heaton, Andy; Miernik, Janie; Stough, Rob; Wright, Roosevelt; Young, Roy

    2012-01-01

    Mission concept is to assess the feasibility of using solar sail propulsion to enable a robotic precursor that would survey multiple Near Earth Objects (NEOs) for potential future human visits. Single spacecraft will rendezvous with and image 3 NEOs within 6 years of launch

  13. Revisión sistemática del Inventario de Personalidad NEO (NEO-PI)

    OpenAIRE

    Renato Zambrano Cruz

    2011-01-01

    Los objetivos del artículo fueron describir la prevalencia de identidad El presente artículo busca establecer la vigencia y aplicabilidad del Inventario de Personalidad NEO (NEO-PI). Para dicho efecto se realizó un estudio de revisión sistemática en donde se encontraron veintiún artículos que cumplían con los criterios de inclusión de la investigación en el periodo 2000-2010. Se encontró un uso constante del instrumento tanto para investigar rasgos de personalidad en diferentes poblaciones...

  14. Principles of Neo-Schumpeterian Economics

    OpenAIRE

    Horst Hanusch; Andreas Pyka

    2005-01-01

    Within the last 25 years large progress has been made in Neo-Schumpeterian Economics, this branch of economic literature which deals with dynamic processes causing qualitative transformation of economies basically driven by the introduction of novelties in their various and multifaceted forms. By its very nature, innovation and in particular technological innovation is the most exponent and most visible form of novelty. Therefore it is not very surprising that Neo-Schumpeterian Economics toda...

  15. Using Item Response Theory to Develop a 60-Item Representation of the NEO PI-R Using the International Personality Item Pool: Development of the IPIP-NEO-60.

    Science.gov (United States)

    Maples-Keller, Jessica L; Williamson, Rachel L; Sleep, Chelsea E; Carter, Nathan T; Campbell, W Keith; Miller, Joshua D

    2017-10-31

    Given advantages of freely available and modifiable measures, an increase in the use of measures developed from the International Personality Item Pool (IPIP), including the 300-item representation of the Revised NEO Personality Inventory (NEO PI-R; Costa & McCrae, 1992a ) has occurred. The focus of this study was to use item response theory to develop a 60-item, IPIP-based measure of the Five-Factor Model (FFM) that provides equal representation of the FFM facets and to test the reliability and convergent and criterion validity of this measure compared to the NEO Five Factor Inventory (NEO-FFI). In an undergraduate sample (n = 359), scores from the NEO-FFI and IPIP-NEO-60 demonstrated good reliability and convergent validity with the NEO PI-R and IPIP-NEO-300. Additionally, across criterion variables in the undergraduate sample as well as a community-based sample (n = 757), the NEO-FFI and IPIP-NEO-60 demonstrated similar nomological networks across a wide range of external variables (r ICC = .96). Finally, as expected, in an MTurk sample the IPIP-NEO-60 demonstrated advantages over the Big Five Inventory-2 (Soto & John, 2017 ; n = 342) with regard to the Agreeableness domain content. The results suggest strong reliability and validity of the IPIP-NEO-60 scores.

  16. ExploreNEOs: The Warm Spitzer Near Earth Object Survey

    NARCIS (Netherlands)

    Trilling, D. E.; Hora, J. L.; Mueller, M.; Thomas, C. A.; Harris, A. W.; Hagen, A. R.; Mommert, M.; Benner, L.; Bhattacharya, B.; Bottke, W. F.; Chesley, S.; Delbo, M.; Emery, J. P.; Fazio, G.; Kistler, J. L.; Mainzer, A.; Morbidelli, A.; Penprase, B.; Smith, H. A.; Spahr, T. B.; Stansberry, J. A.

    2012-01-01

    We have observed some 600 near Earth objects (NEOs) at 3.6 and 4.5 microns with the Warm Spitzer Space Telescope. We derive the albedo and diameter for each NEO to characterize global properties of the NEO population, among other goals.

  17. Spent fuel management: Current status and prospects 1997. Proceedings of a regular advisory group meeting

    International Nuclear Information System (INIS)

    1998-03-01

    Spent fuel management has always been one of the important stages in the nuclear fuel cycle and it is still most vital problems common to all countries with nuclear reactors. It begins with the discharge of spent fuel from a power or a research reactor and ends with its ultimate disposition. Two options exist - an open, once-through cycle with direct disposal of the spent fuel and a closed cycle with reprocessing of the spent fuel, recycling of reprocessed plutonium and uranium in new mixed oxide fuels and disposal of the radioactive waste. Continuous attention is being given by the IAEA to the collection, analysis and exchange of information on spent fuel management. Its role in this area is to provide a forum for exchanging information and to co-ordinate and to encourage closer co-operation among Member States in certain research and development activities that are of common interest. Spent fuel management is recognized as a high priority IAEA activity. The Regular Advisory Group on Spent Fuel Management was established in 1982. The objective of the Regular Advisory Group is to serve as a means of exchanging information on the current status and progress of national programmes on spent fuel management and to provide advice to the IAEA. The results of the last Regular Advisory Group meeting (9-12 September 1997) are reflected in this report. It gives an overview of the status of spent fuel management programmes in a number of countries, a description of the current status and prospects of activities in this field and recommendations of the participants

  18. Accelerated pseudogenization on the neo-X chromosome in Drosophila miranda

    KAUST Repository

    Nozawa, Masafumi

    2016-11-29

    Y chromosomes often degenerate via the accumulation of pseudogenes and transposable elements. By contrast, little is known about X-chromosome degeneration. Here we compare the pseudogenization process between genes on the neo-sex chromosomes in Drosophila miranda and their autosomal orthologues in closely related species. The pseudogenization rate on the neo-X is much lower than the rate on the neo-Y, but appears to be higher than the rate on the orthologous autosome in D. pseudoobscura. Genes under less functional constraint and/or genes with male-biased expression tend to become pseudogenes on the neo-X, indicating the accumulation of slightly deleterious mutations and the feminization of the neo-X. We also find a weak trend that the genes with female-benefit/male-detriment effects identified in D. melanogaster are pseudogenized on the neo-X, implying the masculinization of the neo-X. These observations suggest that both X and Y chromosomes can degenerate due to a complex suite of evolutionary forces.

  19. The Netherlands Epidemiology of Obesity (NEO) study: study design and data collection.

    Science.gov (United States)

    de Mutsert, Renée; den Heijer, Martin; Rabelink, Ton Johannes; Smit, Johannes Willem Adriaan; Romijn, Johannes Anthonius; Jukema, Johan Wouter; de Roos, Albert; Cobbaert, Christa Maria; Kloppenburg, Margreet; le Cessie, Saskia; Middeldorp, Saskia; Rosendaal, Frits Richard

    2013-06-01

    Obesity is a well-established risk factor for many chronic diseases. Incomplete insight exists in the causal pathways responsible for obesity-related disorders and consequently, in the identification of obese individuals at risk of these disorders. The Netherlands Epidemiology of Obesity (NEO) study is designed for extensive phenotyping to investigate pathways that lead to obesity-related diseases. The NEO study is a population-based, prospective cohort study that includes 6,673 individuals aged 45-65 years, with an oversampling of individuals with overweight or obesity. At baseline, data on demography, lifestyle, and medical history have been collected by questionnaires. In addition, samples of 24-h urine, fasting and postprandial blood plasma and serum, and DNA were collected. Participants underwent an extensive physical examination, including anthropometry, electrocardiography, spirometry, and measurement of the carotid artery intima-media thickness by ultrasonography. In random subsamples of participants, magnetic resonance imaging of abdominal fat, pulse wave velocity of the aorta, heart, and brain, magnetic resonance spectroscopy of the liver, indirect calorimetry, dual-energy X-ray absorptiometry, or accelerometry measurements were performed. The collection of data started in September 2008 and completed at the end of September 2012. Participants are followed for the incidence of obesity-related diseases and mortality. The NEO study investigates pathways that lead to obesity-related diseases. A better understanding of the mechanisms underlying the development of disease in obesity may help to identify individuals who are susceptible to the detrimental metabolic, cardiovascular and other consequences of obesity and has implications for the development of prevention and treatment strategies.

  20. Neo-Lamarckism in Portugal

    Directory of Open Access Journals (Sweden)

    Almaça, Carlos

    2000-12-01

    Full Text Available

    Darwinism was championed in Portugal by the University and progressionist political parties from the 1860's on. Neo-Darwinism was neglected in its proper time and so the acceptance of the inheritance of acquired characters continued over the first decades of the 20th century. Men of medical education who were professors of Biology at the University of Oporto supported neo-Lamarckian theories in early 20th century. The first one has been Américo Pires de Lima (1886-1966, professor of Botany, whose doctoral dissertation sustaining early Darwinism and neo-Lamarckism was presented in 1912. This thesis, as well as a few neo-Lamarckian publications with antropological significance, are commented and discussed in the present paper.



    El Darwinismo fue defendido en Portugal en la Universidad y por los partidos políticos progresistas durante la década de los años 60 del siglo XIX. El neo-darwinismo fue ignorado en su tiempo y así continuó la aceptación de la herencia de los caracteres adquiridos a lo largo de las primeras décadas del siglo XX. Los profesores de biolog

  1. Neo-liberalisation, Universities and the Values of Bureaucracy

    OpenAIRE

    Nash, Kate

    2018-01-01

    Neo-liberalisation of universities is advancing through a bureaucratic revolution. ‘Marketising bureaucracy’ advances neo-liberalisation through audit and rankings in the name of ensuring value for money and consumer choice. However, bureaucracy in universities is not total, just as neo-liberalisation is a project which advances on an uneven terrain of values. This article argues that to exercise academic autonomy, to continue to value education, we must learn to distinguish between ‘marketis...

  2. Innovative nuclear fuels: results and strategy

    International Nuclear Information System (INIS)

    Stan, Marius

    2009-01-01

    To facilitate the discovery and design of innovative nuclear fuels, multi-scale models and simulations are used to predict irradiation effects on the thermal conductivity, oxygen diffusivity, and thermal expansion of oxide fuels. The multi-scale approach is illustrated using results on ceramic fuels with a focus on predictions of point defect concentrations, stoichiometry, and phase stability. The high performance computer simulations include coupled heat transport, diffusion, and thermal expansion, gas bubble formation and temperature evolution in a fuel element consisting of UO2 fuel and metallic cladding. The second part of the talk is dedicated to a discussion of an international strategy for developing advanced, innovative nuclear fuels. Four initiative are proposed to accelerate the discovery and design of new materials: (a) Develop an international pool of experts, (b) Create Institutes for Materials Discovery and Design, (c) Create an International Knowledge base for experimental data, models (mathematical expressions), and simulations (codes) and (d) Organize international workshops and conference sessions. The paper ends with a discussion of existing and emerging international collaborations.

  3. ExploreNEOs: The Warm Spitzer Near Earth Object survey

    NARCIS (Netherlands)

    Mueller, M.; Trilling, D. E.; Hora, J. L.; Harris, A. W.; Benner, L. A. M.; Bhattacharya, B.; Bottke, W. F.; Chesley, S.; Delbó, M.; Emery, J. P.; Fazio, G.; Hagen, A. R.; Kistler, J. L.; Mainzer, A.; Mommert, M.; Morbidelli, A.; Penprase, B.; Smith, H. A.; Spahr, T. B.; Stansberry, J. A.; Thomas, C. A.

    2011-01-01

    We are carrying out the ExploreNEOs project in which we observe more than 600 near Earth Objects (NEOs) at 3.6 and 4.5 microns with Warm Spitzer. For each NEO we derive diameter and albedo. We present our results to date, which include studies of individual objects, results for our entire observed

  4. Neo-Conservatives as Social Darwinists: Implications for Higher Education.

    Science.gov (United States)

    Sola, Peter; And Others

    1986-01-01

    Compares the Social Darwinism of the 1890s with neo-conservatism of the 1980s. Discusses the ideologies of fair play versus fair shares, the theory of supply-side economics, and the implications of neo-conservatism for higher education. Argues that neo-conservatism is altering radically our conceptions of democracy, equality, and freedom. (KH)

  5. Uruguay minerals fuels[Study of Uranium geochemical prospection in Uruguay]; Los combustibles minerales del Uruguay

    Energy Technology Data Exchange (ETDEWEB)

    Goso, H

    1967-07-01

    In this report the bases for the development of the necessary works of prospection are exposed on mineral fuels of Uruguay. We have taken the set from: coal, lutitas bituminous, uranium, petroleum and disturbs. In all the cases we have talked about to the present state of the knowledge and to the works that we considered necessary to develop in each case.

  6. Neo-logistic model for the growth of bacteria

    OpenAIRE

    Tashiro, Tohru; Yoshimura, Fujiko

    2017-01-01

    We propose a neo-logistic model that can describe bacterial growth data precisely. This model is not derived by modifying the logistic model formally, but by incorporating the synthesis of inducible enzymes into the logistic model indirectly. Therefore, the meaning of the parameters of the neo-logistic model becomes physically clear. The neo-logistic model can approximate bacterial growth better than models previously presented, and predict the order of the saturated number of bacteria in the...

  7. Mean Profiles of the NEO Personality Inventory

    Czech Academy of Sciences Publication Activity Database

    Allik, J.; Church, A.T.; Ortiz, F. A.; Rossier, J.; Hřebíčková, Martina; De Fruyt, F.; Realo, A.; McCrae, R. R.

    2017-01-01

    Roč. 48, č. 3 (2017), s. 402-420 ISSN 0022-0221 Institutional support: RVO:68081740 Keywords : personality * five-factor model * cross-cultural research * traits * country mean scores * NEO-PI-R * NEO-PI-3 Subject RIV: AN - Psychology OBOR OECD: Psychology (including human - machine relations) Impact factor: 1.657, year: 2016

  8. 13 CFR 142.25 - Can a party or witness object to discovery?

    Science.gov (United States)

    2010-01-01

    ... discovery? 142.25 Section 142.25 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION PROGRAM FRAUD CIVIL REMEDIES ACT REGULATIONS Hearing Provisions § 142.25 Can a party or witness object to discovery? Any party or prospective witness may file a motion to quash a subpoena or to limit discovery or the...

  9. Alternate aircraft fuels prospects and operational implications

    Science.gov (United States)

    Witcofski, R. D.

    1977-01-01

    The paper discusses NASA studies of the potentials of coal-derived aviation fuels, specifically synthetic aviation kerosene, liquid methane, and liquid hydrogen. Topics include areas of fuel production, air terminal requirements for aircraft fueling (for liquid hydrogen only), and the performance characteristics of aircraft designed to utilize alternate fuels. Energy requirements associated with the production of each of the three selected fuels are determined, and fuel prices are estimated. Subsonic commercial air transports using liquid hydrogen fuel have been analyzed, and their performance and the performance of aircraft which use commercial aviation kerosene are compared. Environmental and safety issues are considered.

  10. NEO osobnostní inventář (NEO-PI-3) v diagnostice osobnosti dětí a adolescentů

    Czech Academy of Sciences Publication Activity Database

    Hřebíčková, Martina

    2008-01-01

    Roč. 52, č. 5 (2008), s. 425-442 ISSN 0009-062X R&D Projects: GA ČR GA406/07/1561 Institutional research plan: CEZ:AV0Z70250504 Keywords : personality * five-factor model * NEO Personality Inventory * NEO-PI-3 * adolescents Subject RIV: AN - Psychology Impact factor: 0.101, year: 2008

  11. Vnitřní konzistence české verze NEO osobnostního inventáře (NEO-PI-R)

    Czech Academy of Sciences Publication Activity Database

    Hřebíčková, Martina

    2002-01-01

    Roč. 46, č. 6 (2002), s. 521-535 ISSN 0009-062X Institutional research plan: CEZ:AV0Z7025918 Keywords : Five-factor model of personality * NEO Personality Inventory (NEO-PI-R) * basic psychometric characteristics Subject RIV: AN - Psychology Impact factor: 0.190, year: 2002

  12. Liquid fuel resources and prospects for ligno-cellulosic ethanol: An Egyptian case study

    Directory of Open Access Journals (Sweden)

    Shadia R. Tewfik

    2013-12-01

    Full Text Available Fossil fuels (oil, natural gas and coal presently represent about 90% of the world’s total commercial primary energy demand. Yet, they are depletable sources of energy. Growth in the production of easily accessible oil, the main source of high energy liquid transportation fuels, will not match the projected rate of demand growth, especially in developing countries. In the transport sector, today, the only alternative to non-sustainable fossil fuels is biofuels that are produced from biomass, a stored environmentally neutral solar energy. These fuels are compatible with current vehicles and blendable with conventional fuels. Moreover, they share the long-established distribution infrastructure with little, if any, modification of equipment. The main biofuels presently in commercial production are bioethanol and biodiesel. Industrial countries started production of the 1st generation bioethanol and biodiesel from food products (grains and edible oil since a few decades and these fuels are currently available at petrol stations. Second generation bioethanol from ligno-cellulosic materials is on the research, pilot and/or demonstration stage. This paper discusses the current situation regarding liquid fuels in Egypt which are experiencing imbalance between total production and demand for gasoline and diesel fuels. The quantified need for nonconventional sources is presented. Based on a thorough assessment of current and prospective generated agriculture residues as distributed over the political areas, mapping of the number and capacity of plants to be installed for production of bioethanol from available residues namely rice straw, sugar cane residues and cotton stalks has been developed. Annual capacities of 3000, 10,000 and 20,000 tons ethanol/year until year 2021 have been proposed. Capital and operating requirements and economic indicators have been estimated. It has been concluded that at current price of ethanol of about $0.6/kg, the

  13. Computing risk for oil prospects: principles and programs

    International Nuclear Information System (INIS)

    Harbaugh, J.W.; Davis, J.C.; Wendebourg, J.

    1995-01-01

    This volume in the series Computer Methods in the Geosciences examines the challenge of risk assessment, field size distributions, and success, sequence and gambler's ruin. The estimation of the discovery size from the prospect size, outcome probabilities and success ratios, modeling prospects, and mapping properties and uncertainties are reviewed, and discriminating discoveries and dry holes, forecasting cash flow for a prospect, the worth of money, and use of risk analysis tables, decision tables and trees are considered. Appendices cover the installation of the RISK program and user manuals, and two disks are included with the volume. (UK)

  14. Theranostic Perspectives in Prostate Cancer with the Gastrin-Releasing Peptide Receptor Antagonist NeoBOMB1: Preclinical and First Clinical Results.

    Science.gov (United States)

    Nock, Berthold A; Kaloudi, Aikaterini; Lymperis, Emmanouil; Giarika, Athina; Kulkarni, Harshad R; Klette, Ingo; Singh, Aviral; Krenning, Eric P; de Jong, Marion; Maina, Theodosia; Baum, Richard P

    2017-01-01

    (>95% intact at 5 min after injection). After injection in mice, all 3 ( 67 Ga-, 111 In-, and 177 Lu-NeoBOMB1) showed comparably high and GRPR-specific uptake in the PC-3 xenografts (e.g., 30.6 ± 3.9, 28.6 ± 6.0, and >35 percentage injected dose per gram at 4 h after injection, respectively), clearing from background predominantly via the kidneys. During a translational study in prostate cancer patients, 68 Ga-NeoBOMB1 rapidly localized in pathologic lesions, achieving high-contrast imaging. The GRPR antagonist radioligands 67 Ga-, 111 In-, and 177 Lu-NeoBOMB1, independent of the radiometal applied, have shown comparable behavior in prostate cancer models, in favor of future theranostic use in GRPR-positive cancer patients. Such translational prospects were further supported by the successful visualization of prostate cancer lesions in men using 68 Ga-NeoBOMB1 and PET/CT. © 2017 by the Society of Nuclear Medicine and Molecular Imaging.

  15. Neo-Ottomanism" in the Regional Policy of Turkey

    Directory of Open Access Journals (Sweden)

    Elnur Tadzhaddinovich Mehdiyev

    2016-01-01

    Full Text Available The article is devoted to the ideology of Turkey's foreign policy. The term "neo-Ottomanism" is increasingly used in recent years in relation to the Turkish foreign policy. The concept of neo-Ottomanism, which ideology is the Prime Minister Davutoglu, implies a relationship of foreign policy of modern Turkey with the historical heritage of the Ottomans and its focus on return "last Ottoman", taking into account today's realities. The author examines this phenomenon in the context of the regional policy of Turkey in this period. The main directions of the strategy of neo are the Middle East, North Africa, Central Asia, the Caucasus, the Crimea, and the Balkans. Particular attention is paid to manifestations of neo-Ottomanism in the post-Soviet region and the Middle East, as well as "soft power" strategy in the Turkish neo-Ottomanism. Activities of Ankara in the regions belonging to the sphere of its geopolitical interests is carried out on political, economic, religious, cultural and educational levels. Rapprochement with the political and business circles of influence of countries in the region is aimed at the formation of pro-Turkish lobby. "Arab Spring" has given Turkey a historic opportunity to realize its neo-Ottoman ambitions and create a new order in the Middle East. Turkey's rapprochement with the Islamic world during the 'Arab Spring' demonstrated that Ankara supported in conjunction with the Western nations protest and opposition movements in Egypt, Libya and Tunisia, aims to demonstrate to the West the growth of its influence in the region. Mediation is used in regional conflicts Turkish leadership as an instrument of "soft power", with which Ankara aims to increase its international and regional credibility. The result of "neo-Ottoman" Turkey's policy in relations with Russia became a serious crisis in all spheres of cooperation. Strategic mistakes made by the head of the republic R. Erdogan in the settlement of the Syrian crisis, may

  16. Prospecting history leading to the discovery of Botswana's diamond mines: from artefacts to Lesedi La Rona

    Science.gov (United States)

    de Wit, Michiel C. J.

    2018-02-01

    Bechuanaland/Botswana has a long and colourful history in exploration and mining. Here these activities are subdivided into three phases: pre-historic, historic and modern. Quarrying stone in Botswana was ongoing 500,000 years ago during the Early Stone Age (ESA). Actual mining of stones probably only started during the Middle Stone Age (MSA) i.e. post 250,000 BP, and the first prehistoric hard rock mining of specularite and limonite, likely started during the Late Stone Age (LSA) 20,000 to 2,000 BP. In east Botswana iron and copper were mined from AD 800 onwards; the mining of gold started in the thirteenth century. Historic mining started with the re-discovery of gold close to Francistown in 1865 and lasted until the 1950s. Rumours of diamonds in Bechuanaland had already surfaced in the 1880s, and it was Ngamiland, in the northwest, that was first explored systematically for diamonds and gold between 1896 and 1899. A joint initiative between Anglo American and De Beers started serious prospecting parts of eastern Bechuanaland between 1932 and 1938; and in 1938 the first diamond finds in Bechuanaland were reported. Modern mining and exploration started with the signing of an agreement in 1959, allowing Consolidated African Selection Trust Ltd (CAST) into the Bamangwato Tribal Reserve. CAST found a few diamonds in the Motloutse River, but concluded that these were reworked and dropped the exploration rights. De Beers believed that these diamonds had come from west of the Motloutse headwaters, across the watershed in the Kalahari. This ultimately led to the discovery of the Orapa kimberlite field in 1967, a year after Botswana became independent. This discovery triggered a major exploration boom across Botswana adding important diamond-bearing kimberlites such as at Letlhakane (1968), Jwaneng (1973), Gope (1981) and Lerala (1991).

  17. NeoPHOX – a structurally tunable ligand system for asymmetric catalysis

    Directory of Open Access Journals (Sweden)

    Jaroslav Padevět

    2016-06-01

    Full Text Available A synthesis of new NeoPHOX ligands derived from serine or threonine has been developed. The central intermediate is a NeoPHOX derivative bearing a methoxycarbonyl group at the stereogenic center next to the oxazoline N atom. The addition of methylmagnesium chloride leads to a tertiary alcohol, which can be acylated or silylated to produce NeoPHOX ligands with different sterical demand. The new NeoPHOX ligands were tested in the iridium-catalyzed asymmetric hydrogenation and palladium-catalyzed allylic substitution. In both reactions high enantioselectivities were achieved, that were comparable to the enantioselectivities obtained with the up to now best NeoPHOX ligand derived from expensive tert-leucine.

  18. Against the Anthropocene. A Neo-Materialist Perspective

    Directory of Open Access Journals (Sweden)

    Timothy James LeCain

    2015-04-01

    Full Text Available The dawning realization that the planet may have entered a new geological epoch called the Anthropocene could prove transformative. However, over the course of its brief history, the Anthropocene concept has often been framed in ways that reinforce, rather than challenge, the conventional modernist belief in a clear dividing line between human culture and a largely passive natural world, sharply limiting the concept’s potential utility. Reflecting the overestimation of human agency and power inevitably implied by a term that is often popularly translated as the ‘Age of Humans’, some have already begun to argue that powerful humans can be trusted to create a so-called ‘Good Anthropocene’ through massive geo-engineering projects. No deeper re-examination of the human relationship to the planet is thus necessary or desired. By contrast, this article draws on emerging neo-materialist theory to suggest a radically different approach that emphasizes the ways in which humans and their cultures have been created by and with a powerful material environment.The technologies of the thermo-industrial revolution are framed not so much as evidence of human power, but as evidence that the material world has a much greater power to shape human minds, cultures, and technologies than has heretofore been recognized by most scholars.From a neo-materialist perspective, the new geological epoch might be better termed the Carbocene: an age of powerful carbon-based fuels that have helped to create ways of thinking and acting that humans now find exceedingly difficult to escape. Might a more humble and cautious view of a creative and potentially dangerous planet offer a more effective means of spurring progress in combating global climate change than the misleading anthropocentrism inherent in a term like the Anthropocene?

  19. Prospects for UK fuel cells component suppliers

    Energy Technology Data Exchange (ETDEWEB)

    Wilcox, C.; Tunnicliffe, M.

    2002-07-01

    This report examines the capabilities of the UK fuel cell industry in meeting the expected increase in demand, and aims to identify all UK suppliers of fuel cell components, evaluate their products and match them to fuel cell markets, and identify components where the UK is in a competitive position. Component areas are addressed along with the need to reduce costs and ensure efficient production. The well established supplier base in the UK is noted, and the car engine manufacturing base and fuel supply companies are considered. The different strengths of UK suppliers of the various types of fuel cells are listed. The future industry structure, the opportunities and dangers for business posed by fuel cells, the investment in cleaner technologies by the large fuel companies, opportunities for catalyst suppliers, and the residential combined heat and power and portable electronics battery markets are discussed.

  20. Enfisema subcutâneo maciço – Tratamento com drenos subcutâneos

    Directory of Open Access Journals (Sweden)

    Maria Sucena

    2010-03-01

    Full Text Available Resumo: O enfisema subcutâneo é uma complicação relativamente comum na sequência de técnicas invasivas, procedimentos cirúrgicos e algumas patologias médicas. Na maior parte dos casos apenas causa sintomatologia minor e o tratamento é habitualmente conservador. Mesmo quando grave, raramente tem consequências patofisiológicas significativas, apesar de ser extremamente desconfortável para o doente.Os autores descrevem um caso clínico de enfisema subcutâneo maciço, de rápida instalação, após saída acidental de tubo de drenagem torácica, em doentecom pneumotórax espontâneo secundário e fístula broncopleural. O enfisema foi tratado através da colocação, sob anestesia local, de dois drenos subcutâneos na parede anterossuperior do tórax, conectados a sacos de drenagem. Após a colocação dos drenos subcutâneos verificou-se uma franca melhoria clínica do doente, com descompressão eficaz do enfisema subcutâneo. No presente caso clínico, a técnica de drenagem do enfisema maciço mostrou-se simples, segura e eficaz, permitindo o alívio sintomático imediato.Rev Port Pneumol 2010; XVI (2: 321-329 Abstract: Massive subcutaneous emphysema is a relatively common complication in invasive techniques, surgical practice and some medical conditions. Subcutaneous emphysema is usually treated conservatively and may only cause minimal symptoms. Even when it is severe, subcutaneous emphysema rarely has pathophysiologic consequences, but it is extremely uncomfortable for the patient.The authors report a case of massive and rapid developing subcutaneous emphysema following chest tube displacement in a patient with spontaneous secondary pneumothorax and large air leak. The emphysema was treated with two subcutaneous drains, inserted using local anesthesia, on both sides of the chest (antero-superior thoracic wall, connected to drainage bags. The drains

  1. Alzheimer's Disease Sequencing Project discovery and replication criteria for cases and controls: Data from a community-based prospective cohort study with autopsy follow-up.

    Science.gov (United States)

    Crane, Paul K; Foroud, Tatiana; Montine, Thomas J; Larson, Eric B

    2017-12-01

    The Alzheimer's Disease Sequencing Project (ADSP) used different criteria for assigning case and control status from the discovery and replication phases of the project. We considered data from a community-based prospective cohort study with autopsy follow-up where participants could be categorized as case, control, or neither by both definitions and compared the two sets of criteria. We used data from the Adult Changes in Thought (ACT) study including Diagnostic and Statistical Manual-IV criteria for dementia status, McKhann et al. criteria for clinical Alzheimer's disease, and Braak and Consortium to Establish a Registry for AD findings on neurofibrillary tangles and neuritic plaques to categorize the 621 ACT participants of European ancestry who died and came to autopsy. We applied ADSP discovery and replication definitions to identify controls, cases, and people who were neither controls nor cases. There was some agreement between the discovery and replication definitions. Major areas of discrepancy included the finding that only 40% of the discovery sample controls had sufficiently low levels of neurofibrillary tangles and neuritic plaques to be considered controls by the replication criteria and the finding that 16% of the replication phase cases were diagnosed with non-AD dementia during life and thus were excluded as cases for the discovery phase. These findings should inform interpretation of genetic association findings from the ADSP. Differences in genetic association findings between the two phases of the study may reflect these different phenotype definitions from the discovery and replication phase of the ADSP. Copyright © 2017 the Alzheimer's Association. Published by Elsevier Inc. All rights reserved.

  2. CANDU market prospects

    International Nuclear Information System (INIS)

    Kakaria, B.K.

    1994-01-01

    This 1994 survey of prospective markets for CANDU reactors discusses prospects in Turkey, Thailand, the Philippines, Korea, Indonesia, China and Egypt, and other opportunities, such as in fuel cycles and nuclear safety. It was concluded that foreign partners would be needed to help with financing

  3. The Neo-Victorian Novel, 1990-2010

    OpenAIRE

    Worthington, Julia

    2013-01-01

    The final decade of the twentieth century and the first decade of the twenty-first witnessed a surge of published novels with direct and indirect connection to the Victorian era, at a time when a focus on the new millenium might have been expected. This proliferation of what came to be termed 'neo-Victorian novels' shows no sign of abating and has now given rise to scholarly research on the subject. The principal aim of this thesis is to examine the rise of the neo-Victorian novel during ...

  4. Neo-classical economics, institutional economics and improved fisheries management

    NARCIS (Netherlands)

    van der Burg, Tsjalle

    2000-01-01

    According to neo-classical economists, taxes and individual transferable quotas (ITQs) are the most efficient measures for dealing with the problem of overfishing. Institutional economists, however, criticise neo-classical economists for neglecting political problems, enforcement problems and

  5. ExploreNEOs. III. PHYSICAL CHARACTERIZATION OF 65 POTENTIAL SPACECRAFT TARGET ASTEROIDS

    International Nuclear Information System (INIS)

    Mueller, Michael; Delbo', M.; Hora, J. L.; Fazio, G.; Smith, H. A.; Spahr, T. B.; Trilling, D. E.; Thomas, C. A.; Bhattacharya, B.; Bottke, W. F.; Chesley, S.; Mainzer, A.; Emery, J. P.; Harris, A. W.; Mommert, M.; Penprase, B.; Stansberry, J. A.

    2011-01-01

    Space missions to near-Earth objects (NEOs) are being planned at all major space agencies, and recently a manned mission to an NEO was announced as a NASA goal. Efforts to find and select suitable targets (plus backup targets) are severely hampered by our lack of knowledge of the physical properties of dynamically favorable NEOs. In particular, current mission scenarios tend to favor primitive low-albedo objects. For the vast majority of NEOs, the albedo is unknown. Here we report new constraints on the size and albedo of 65 NEOs with rendezvous Δv -1 . Our results are based on thermal-IR flux data obtained in the framework of our ongoing (2009-2011) ExploreNEOs survey using NASA's 'Warm-Spitzer' space telescope. As of 2010 July 14, we have results for 293 objects in hand (including the 65 low-Δv NEOs presented here); before the end of 2011, we expect to have measured the size and albedo of ∼700 NEOs (including probably ∼160 low-Δv NEOs). While there are reasons to believe that primitive volatile-rich materials are universally low in albedo, the converse need not be true: the orbital evolution of some dark objects likely has caused them to lose their volatiles by coming too close to the Sun. For all our targets, we give the closest perihelion distance they are likely to have reached (using orbital integrations from Marchi et al. 2009) and corresponding upper limits on the past surface temperature. Low-Δv objects for which both albedo and thermal history may suggest a primitive composition include (162998) 2001 SK162, (68372) 2001 PM9, and (100085) 1992 UY4.

  6. Neumomediastino espontáneo recidivante

    Directory of Open Access Journals (Sweden)

    Damaris Reyes Hernández

    2017-12-01

    Full Text Available El neumomediastino espontáneo se caracteriza por la presencia de aire en el mediastino. Es una enfermedad generalmente benigna y autolimitada, no asociada a causa directa conocida. Es de infrecuente ocurrencia. Se presenta principalmente con dolor torácico, disnea y enfisema subcutáneo. El diagnóstico se realiza sobre la base del cuadro clínico y radiografía o tomografía axial computarizada de tórax. Se presenta el caso de un paciente masculino de 17 años de edad, atleta de alto rendimiento, que comienza de forma súbita con dolor torácico, disnea y enfisema subcutáneo. Se le realizó radiografía de tórax en la que se observa la presencia de aire en el mediastino, y se corrobora el diagnóstico de neumomediastino mediante tomografía axial computarizada de tórax. Recibió tratamiento conservador con mejoría evidente. Aunque la literatura reporta que no es habitual la recurrencia, en el paciente que se presenta hubo recidiva del neumomediastino a los tres meses del primer evento. Se presenta este caso por lo infrecuente de esta enfermedad y su recurrencia.

  7. The LCO Follow-up and Characterization Network and AgentNEO Citizen Science Project

    Science.gov (United States)

    Lister, Tim; Greenstreet, Sarah; Gomez, Edward; Christensen, Eric J.; Larson, Stephen M.

    2017-10-01

    The LCO NEO Follow-up Network is using the telescopes of the Las Cumbres Observatory (LCO) and a web-based target selection, scheduling and data reduction system to confirm NEO candidates and characterize radar-targeted known NEOs. Starting in July 2014, the LCO NEO Follow-up Network has observed over 4,500 targets and reported more than 25,000 astrometric and photometric measurements to the Minor Planet Center.The LCO NEO Follow-up Network's main aims are to perform confirming follow-up of the large number of NEO candidates and to perform characterization measurements of radar targets to obtain light curves and rotation rates. The NEO candidates come from the NEO surveys such as Catalina, PanSTARRS, ATLAS, NEOWISE and others. In particular, we are targeting objects in the Southern Hemisphere, where the LCO NEO Follow-up Network is the largest resource for NEO observations.The first phase of the LCO Network comprises nine 1-meter and seven 0.4-meter telescopes at site at McDonald Observatory (Texas), Cerro Tololo (Chile), SAAO (South Africa) and Siding Spring Observatory (Australia). The network has been fully operational since 2014 May, and observations are being executed remotely and robotically. Additional 0.4-meter telescopes will be deployed in 2017 and 2x1-meter telescopes for a site at Ali Observatory, Tibet are planned for 2018-2019.We have developed web-based software called NEOexchange which automatically downloads and aggregates NEO candidates from the Minor Planet Center's NEO Confirmation Page, the Arecibo and Goldstone radar target lists and the NASA lists. NEOexchange allows the planning and scheduling of observations on the LCO Telescope Network and the tracking of the resulting blocks and generated data. We have extended the NEOexchange software to include automated scheduling and moving object detection, with the results presented to the user via the website.We will present results from the LCO NEO Follow-up Network and from the development of the

  8. Spent fuel management: Current status and prospects

    International Nuclear Information System (INIS)

    1988-12-01

    The main objective of the Advisory Group on Spent Fuel Management is to review the world-wide situation in Spent Fuel Management, to define the most important directions of national efforts and international cooperation in this area, to exchange information on the present status and progress in performing the back-end of Nuclear Fuel Cycle and to elaborate the general recommendations for future Agency programmes in the field of spent fuel management. This report which is a result of the third IAEA Advisory Group Meeting (the first and second were held in 1984 and 1986) is intended to provide the reader with an overview of the status of spent fuel management programmes in a number of leading countries, with a description of the past and present IAEA activities in this field of Nuclear Fuel Cycle and with the Agency's plans for the next years, based on the proposals and recommendations of Member States. A separate abstract was prepared for each of 14 papers presented at the advisory group meeting. Refs, figs and tabs

  9. Neo-classical impurity transport

    International Nuclear Information System (INIS)

    Stringer, T.E.

    The neo-classical theory for impurity transport in a toroidal plasma is outlined, and the results discussed. A general account is given of the impurity behaviour and its dependence on collisionality. The underlying physics is described with special attention to the role of the poloidal rotation

  10. Historicism and neo-Kantianism.

    Science.gov (United States)

    Beiser, Fred

    2008-12-01

    This article treats the conflict between historicism and neo-Kantianism in the late nineteenth century by a careful examination of the writings of Wilhelm Windelband, the leader of the Southwestern neo-Kantians. Historicism was a profound challenge to the fundamental principles of Kant's philosophy because it seemed to imply that there are no universal and necessary principles of science, ethics or aesthetics. Since all such principles are determined by their social and historical context, they differ with each culture and epoch. Windelband attempted to respond to the challenge of this relativism by either broadening Kantian principles, so that they could accommodate the results of historicism, or by reformulating Kantian principles, so that they were impregnable to historical change. The article examines both aspects of Windelband's strategy in some detail, noting the many changes and different formulations in his views. A final section considers some of the difficulties of Windelband's strategy and concludes that, despite its heroic efforts, it was a failure.

  11. Die onderwysbenadering van enkele neo-humanistiese pedagogiese denkers1

    Directory of Open Access Journals (Sweden)

    Jeannette Steyn

    1990-03-01

    Full Text Available After analysing the works of four American writers concerning education, the following conclusions were arrived at:There has been a move away from the accentuation of the rational, cognitive or reason of man to an accentuation of the irrational, affect or emotion of man. The reason for this movement is anthropological in the sense that it reacts against the technicalization and the scientification of man, which was brought about by the cognitive era of humanism. Accentuating the affective functions of man is the neo-humanist’s answer to the technicalized and scientiftcated estranged man. The aims of this article are to discuss the four neo-humanistic views of education and to answer the question whether a neo-humanistic view is anthropologically balanced. The conclusion was reached that a neo-humanistic view of education is anthropologically unbalanced or dual is tic. The accentuation of the affect or emotion of man leads to the minimization of the other functions of man.

  12. Fast breeder fuel cycle, worldwide and French prospects

    International Nuclear Information System (INIS)

    Rapin, M.

    1982-01-01

    A review is given of fast breeder fuel cycle development from both the technological and the economical points of view. LMFBR fuel fabrication, reactor operation, spent fuel storage and transportation, reprocessing and fuel cycle economics are topics considered. (U.K.)

  13. Neo-Nationalism in Higher Education: Case of South Africa

    Science.gov (United States)

    Lee, Jenny J.

    2017-01-01

    Given the rise of regional hubs, emerging economies are experiencing international student growth as higher education providers in their respective regions. This study examined the neo-national experiences of international students in South Africa. Neo-nationalism refers to a new nationalism based national order in the new global economy. The…

  14. Spent fuel management: Current status and prospects 1993

    International Nuclear Information System (INIS)

    1994-02-01

    Spent fuel management has always been one of the most important stages in the nuclear fuel cycle and it is still one of the most vital problems common to all countries with nuclear reactors. It begins with the discharge of spent fuel from a power or a research reactor and ends with its ultimate disposition, either by direct disposal or by reprocessing of the spent fuel. Two options exist at present - an open, once-through cycle with direct disposal of the spent fuel and a closed cycle with reprocessing of the spent fuel and recycling of plutonium and uranium in new mixed oxide fuels. The selection of a spent fuel strategy is a complex procedure in which many factors have to be weighed, including political, economic and safeguards issues as well as protection of the environment. Continuous attention is being given by the IAEA to the collection, analysis and exchange of information on spent fuel management. Its role in this area is to provide a forum for the exchange of information and to co-ordinate and to encourage closer co-operation among Member States in certain research an development activities that are of common interest. Refs, figs and tabs

  15. Fact reactor fuel alloys: Retrospective and prospective views

    International Nuclear Information System (INIS)

    Nevitt, M.V.

    1989-01-01

    The relationship between the physical metallurgy of the EBR-II metallic fuel, U-5% Fs, and its performance in the reactor are described. An understanding of these relationships, along with the optimal matching of fuel properties to fuel-element design, have been essential in the 23 year successful utilization of the fuel. The knowledge and experience gained are being employed in the current development of a new U-Pu-Zr metallic fuel for a proposed advanced reactor (orig./MM)

  16. Enfisema subcutâneo maciço - Tratamento com drenos subcutâneos Massive subcutaneous emphysema - Management using subcutaneous drains

    Directory of Open Access Journals (Sweden)

    Maria Sucena

    2010-04-01

    Full Text Available O enfisema subcutâneo é uma complicação relativamente comum na sequência de técnicas invasivas, procedimentos cirúrgicos e algumas patologias médicas. Na maior parte dos casos apenas causa sintomatologia minor e o tratamento é habitualmente conservador. Mesmo quando grave, raramente tem consequências patofisiológicas significativas, apesar de ser extremamente desconfortável para o doente. Os autores descrevem um caso clínico de enfisema subcutâneo maciço, de rápida instalação, após saída acidental de tubo de drenagem torácica, em doente com pneumotórax espontâneo secundário e fístula broncopleural. O enfisema foi tratado através da colocação, sob anestesia local, de dois drenos subcutâneos na parede anterossuperior do tórax, conectados a sacos de drenagem. Após a colocação dos drenos subcutâneos verificou-se uma franca melhoria clínica do doente, com descompressão eficaz do enfisema subcutâneo. No presente caso clínico, a técnica de drenagem do enfisema maciço mostrou-se simples, segura e eficaz, permitindo o alívio sintomático imediato.Massive subcutaneous emphysema is a relatively common complication in invasive techniques, surgical practice and some medical conditions. Subcutaneous emphysema is usually treated conservatively and may only cause minimal symptoms. Even when it is severe, subcutaneous emphysema rarely has pathophysiologic consequences, but it is extremely uncomfortable for the patient. The authors report a case of massive and rapid developing subcutaneous emphysema following chest tube displacement in a patient with spontaneous secondary pneumothorax and large air leak. The emphysema was treated with two subcutaneous drains, inserted using local anesthesia, on both sides of the chest (antero-superior thoracic wall, connected to drainage bags. The drains produced a dramatic clinical improvement and provided effective decompression of the subcutaneous emphysema. In this clinical case, the

  17. ARTHUR DANTO: ¿ARTE POST-HISTÓRICO O ARTE CONTEMPORÁNEO?

    OpenAIRE

    R., MARÍA DEL CARMEN OLEAS

    2013-01-01

    Resumen:El arte contemporáneo es un concepto difícil de definir y Arthur Danto, como filósofo del arte ha sido uno de los que ha tratado de hacerlo. La siguiente reflexión intenta una aproximación al pensamiento de Danto sobre el arte contemporáneo al que él llama “arte post histórico”. Para Danto, el arte ha muerto y todo lo que sucede después de su muerte es arte post histórico: es de esta manera que él define al arte contemporáneo. Desde un punto de vista filosófico, el arte contemporáneo ...

  18. What Future for Student Engagement in Neo-Liberal Times?

    Science.gov (United States)

    Zepke, Nick

    2015-01-01

    The paper first examines the context that has given student engagement a very strong profile in higher education. It identifies neo-liberalism as the driving force in the present higher education context and argues that student engagement enjoys an elective affinity with it. While neo-liberalism is dominant, student engagement will be strong. But…

  19. Alternate aircraft fuels: Prospects and operational implications

    Science.gov (United States)

    Witcofski, R. D.

    1977-01-01

    The potential use of coal-derived aviation fuels was assessed. The studies addressed the prices and thermal efficiencies associated with the production of coal-derived aviation kerosene, liquid methane and liquid hydrogen and the air terminal requirements and subsonic transport performance when utilizing liquid hydrogen. The fuel production studies indicated that liquid methane can be produced at a lower price and with a higher thermal efficiency than aviation kerosene or liquid hydrogen. Ground facilities of liquefaction, storage, distribution and refueling of liquid hydrogen fueled aircraft at airports appear technically feasibile. The aircraft studies indicate modest onboard energy savings for hydrogen compared to conventional fuels. Liquid hydrogen was found to be superior to both aviation kerosene and liquid methane from the standpoint of aircraft engine emissions.

  20. Nuclear fission - the unexpected discovery seventy years ago

    International Nuclear Information System (INIS)

    Weis, Michael

    2008-01-01

    Seventy years ago, on December 17, 1938, Otto Hahn, Lise Meitner, and Fritz Strassmann discovered nuclear fission. It was a serendipitous discovery resulting from the consistent pursuit, for many years, of occasionally unexpected radiochemical experimental findings. Hardly any other scientific discovery has had such direct bearing on our life, changing our view of the world. It over-threw the tenet of physics, believed to be incontestable, that the atom was indivisible. The use of nuclear power it has made possible has given rise to immense benefits, but it has also allowed mankind's most dreadful weapon so far to be developed. All this is ample reason seventy years later to recall the discovery, the discoverers and their times. It will also be shown what later generations have made of this discovery, and what economic and ecological prospects it continues to hold. (orig.)

  1. Federalism. Theory and Neo-Functionalism: Elements for an analytical framework

    DEFF Research Database (Denmark)

    Dosenrode, Søren

    2010-01-01

    -McKayian way, is able to explain the cases of ‘big bang’ integration (USA, Australia, Canada), but not an ‘organic’ integration process. Neo-functionalism, on the other hand, is not able to explain this relatively fast form of integration, but it is – in its new version - able to analyze and explain......The purpose of this article is to propose a draft for an analytical frame for analyzing regional integration consisting of federalism theory and neo-functionalism. It starts out discussing the concept of regional integration setting up a stagiest model for categorizing it.Then follows an analysis...... of federalism theory and neo-functionalism. One argument of this article is to understand federalism theory as a regional integration theory. Another is to look at federalism theory as complementary to neo-functionalism when trying to explain regional integration. Federalism theory, in an extended Riker...

  2. Exploring patient experiences of neo-adjuvant chemotherapy for breast cancer.

    Science.gov (United States)

    Beaver, Kinta; Williamson, Susan; Briggs, Jean

    2016-02-01

    Neo-adjuvant chemotherapy is recommended for 'inoperable' locally advanced and inflammatory breast cancers. For operable breast cancers, trials indicate no survival differences between chemotherapy given pre or post-surgery. Communicating evidence based information to patients is complex and studies examining patient experiences of neo-adjuvant chemotherapy are lacking. This study aims to explore the experiences of women who received neo-adjuvant chemotherapy for breast cancer. A qualitative approach using in-depth interviews with 20 women who had completed neo-adjuvant chemotherapy for breast cancer. Interview data were analysed using thematic analysis. The sample included a relatively young group of women, with caring responsibilities. Five main themes emerged: coping with the rapid transition from 'well' to 'ill', information needs and decision making, needing support and empathy, impact on family, and creating a new 'normal'. More support was needed towards the end of chemotherapy, when side effects were at their most toxic, and decisions about forthcoming surgery were being made. Some women were referred to psychological services, but usually when a crisis point had been reached. Information and support would have been beneficial at key time points. This information is vital in developing services and interventions to meet the complex needs of these patients and potentially prevent late referral to psychological services. Specialist oncology nurses are able to develop empathetic relationships with patients and have the experience, knowledge and skills to inform and support women experiencing neo-adjuvant chemotherapy. Targeting key time points and maintaining relationship throughout neo-adjuvant chemotherapy would be highly beneficial. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. NREL Fuels and Engines Research: Maximizing Vehicle Efficiency and

    Science.gov (United States)

    chemistry, conversion, and combustion to the evaluation of advanced fuels in actual engines and vehicles . With fuel chemistry, our scientific discoveries start out small. We use quantum mechanical modeling to explore how fuels with varying chemistry interact with engine and vehicle design. At our Fuel Combustion

  4. Typological and dimensional approach at comparing the Giessen Test (GT) with the NEO-Five-Factor-Inventory (NEO-FFI)

    Science.gov (United States)

    Roth, Marcus; Körner, Annett; Herzberg, Philipp Yorck

    2008-01-01

    Objectives: This article reports comparisons of the Giessen Test (GT) with the NEO-Five-Factor-Inventory (NEO-FFI) based on a dimensional as well as on a typological approach. Method: Data were collected from 1673 subjects (aged between 18 and 96 years) constituting a representative sample of the German population. Results: The results indicate only moderate agreement (ranging from .25 to .61) between the subscales of the two personality inventories. The correspondence seems to be somewhat higher, when the typological approach was used instead of the dimensional approach. Conclusions: The typological approach is less dependent on the underlying questionnaires and provides a useful extension of the dimensional approach. PMID:19742276

  5. Ancient Male Recombination Shaped Genetic Diversity of Neo-Y Chromosome in Drosophila albomicans.

    Science.gov (United States)

    Satomura, Kazuhiro; Tamura, Koichiro

    2016-02-01

    Researchers studying Y chromosome evolution have drawn attention to neo-Y chromosomes in Drosophila species due to their resembling the initial stage of Y chromosome evolution. In the studies of neo-Y chromosome of Drosophila miranda, the extremely low genetic diversity observed suggested various modes of natural selection acting on the nonrecombining genome. However, alternative possibility may come from its peculiar origin from a single chromosomal fusion event with male achiasmy, which potentially caused and maintained the low genetic diversity of the neo-Y chromosome. Here, we report a real case where a neo-Y chromosome is in transition from an autosome to a typical Y chromosome. The neo-Y chromosome of Drosophila albomicans harbored a rich genetic diversity comparable to its gametologous neo-X chromosome and an autosome in the same genome. Analyzing sequence variations in 53 genes and measuring recombination rates between pairs of loci by cross experiments, we elucidated the evolutionary scenario of the neo-Y chromosome of D. albomicans having high genetic diversity without assuming selective force, i.e., it originated from a single chromosomal fusion event, experienced meiotic recombination during the initial stage of evolution and diverged from neo-X chromosome by the suppression of recombination tens or a few hundreds of thousand years ago. Consequently, the observed high genetic diversity on the neo-Y chromosome suggested a strong effect of meiotic recombination to introduce genetic variations into the newly arisen sex chromosome. © The Author 2015. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  6. Practice and prospect of advanced fuel management and fuel technology application in PWR in China

    International Nuclear Information System (INIS)

    Xiao Min; Zhang Hong; Ma Cang; Bai Chengfei; Zhou Zhou; Wang Lei; Xiao Xiaojun

    2015-01-01

    Since Daya Bay nuclear power plant implemented 18-month refueling strategy in 2001, China has completed a series of innovative fuel management and fuel technology projects, including the Ling Ao Advanced Fuel Management (AFM) project (high-burnup quarter core refueling) and the Ningde 18-month refueling project with gadolinium-bearing fuel in initial core. First, this paper gives brief introduction to China's advanced fuel management and fuel technology experience. Second, it introduces practices of the advanced fuel management in China in detail, which mainly focuses on the implementation and progress of the Ningde 18-month refueling project with gadolinium-bearing fuel in initial core. Finally, the paper introduces the practices of advanced fuel technology in China and gives the outlook of the future advanced fuel management and fuel technology in this field. (author)

  7. El Mediterráneo en la Estrategia de Seguridad Nacional 2013

    OpenAIRE

    Marquina Barrio, Antonio

    2014-01-01

    Los planteamientos sobre el Mediterráneo que se realizan en la Estrategia de Seguridad Nacional 2013 son unos planteamientos en buena parte deficientes que no tienen en cuenta profundos cambios acontecidos en el Mediterráneo y su espacio de seguridad en los últimos años. El artículo expone las principales modificaciones que habría que introducir para hacer frente a las simplificaciones y omisiones que la Estrategia de Seguridad Nacional 2013 presenta con respecto al Mediterráneo.

  8. Detection of Extracellular Enzyme Activities in Ganoderma neo-japonicum

    OpenAIRE

    Jo, Woo-Sik; Park, Ha-Na; Cho, Doo-Hyun; Yoo, Young-Bok; Park, Seung-Chun

    2011-01-01

    The ability of Ganoderma to produce extracellular enzymes, including β-glucosidase, cellulase, avicelase, pectinase, xylanase, protease, amylase, and ligninase was tested in chromogenic media. β-glucosidase showed the highest activity, among the eight tested enzymes. In particular, Ganoderma neo-japonicum showed significantly stronger activity for β-glucosidase than that of the other enzymes. Two Ganoderma lucidum isolates showed moderate activity for avicelase; however, Ganoderma neo-japonic...

  9. Prospects of nuclear power in fossil fuel saving

    International Nuclear Information System (INIS)

    Chernavskij, S.Ya.

    1984-01-01

    Economic aspects of the World energy situation are considered. The growth in the world prices for energy and energy resources has demanded to reconstruct the structure of both consumers and primary energy resources. The nuclear power development is one of the most important aspects of this reconstruction. In connection with its development the acceptability of nuclear power technology and possible spheres of its application in different fields of power engineering are considered. When discussing these problems one pays the main attention to the psychological effect and potential measures for its compensation. A forecast estimate is given of specific capital investments in and expenditures on electric energy production for NPPs and conventional power stations for the considered period of 30 years. The estimates are differentiated for the European and Asian parts of the country. The problems of developing nuclear central heating-and-power plants and nuclear thermal stations are discussed. It is pointed out that presently no sufficient experience has been gained in their commerical operation to discuss for sure the prospects of their wide-scale utilization. Results of calculations are presented showing that in the range of high-temperature processes the use of electric energy based on the nuclear power development is more efficient than direct combustion of fossil fuel as estimated with respect to its export at the world market prices

  10. Evolution beyond neo-Darwinism: a new conceptual framework.

    Science.gov (United States)

    Noble, Denis

    2015-01-01

    Experimental results in epigenetics and related fields of biological research show that the Modern Synthesis (neo-Darwinist) theory of evolution requires either extension or replacement. This article examines the conceptual framework of neo-Darwinism, including the concepts of 'gene', 'selfish', 'code', 'program', 'blueprint', 'book of life', 'replicator' and 'vehicle'. This form of representation is a barrier to extending or replacing existing theory as it confuses conceptual and empirical matters. These need to be clearly distinguished. In the case of the central concept of 'gene', the definition has moved all the way from describing a necessary cause (defined in terms of the inheritable phenotype itself) to an empirically testable hypothesis (in terms of causation by DNA sequences). Neo-Darwinism also privileges 'genes' in causation, whereas in multi-way networks of interactions there can be no privileged cause. An alternative conceptual framework is proposed that avoids these problems, and which is more favourable to an integrated systems view of evolution. © 2015. Published by The Company of Biologists Ltd.

  11. Journey from discovery of nuclear fission to accelerator-driven sub-critical reactor systems (ADS)

    International Nuclear Information System (INIS)

    Kapoor, S.S.

    2005-01-01

    The epoch making discovery of nuclear fission in 1939, which resulted purely from the curiosity driven basic research to understand the atomic and nuclear structure has changed the world forever with the onset of a new era in the history of human civilization. The basic nuclear physics research pursued after the discovery of fission has also been of much relevance in the harnessing of nuclear energy. In the recent years, there is considerable interest towards developing accelerator driven sub-critical reactor systems (ADS) for the incineration of the long-lived spent fuel radioactive waste and for the utilization of thorium fuel for nuclear power generation. In this talk, we discuss important milestones in the journey from discovery of nuclear fission to ADS. (author)

  12. Is the GAIN Act a turning point in new antibiotic discovery?

    Science.gov (United States)

    Brown, Eric D

    2013-03-01

    The United States GAIN (Generating Antibiotic Incentives Now) Act is a call to action for new antibiotic discovery and development that arises from a ground swell of concern over declining activity in this therapeutic area in the pharmaceutical sector. The GAIN Act aims to provide economic incentives for antibiotic drug discovery in the form of market exclusivity and accelerated drug approval processes. The legislation comes on the heels of nearly two decades of failure using the tools of modern drug discovery to find new antibiotic drugs. The lessons of failure are examined herein as are the prospects for a renewed effort in antibiotic drug discovery and development stimulated by new investments in both the public and private sector.

  13. Effects of positive impression management on the NEO Personality Inventory--Revised in a clinical population.

    Science.gov (United States)

    Ballenger, J F; Caldwell-Andrews, A; Baer, R A

    2001-06-01

    Sixty adults in outpatient psychotherapy completed the NEO Personality Inventory--Revised (NEO PI-R, P. T. Costa & R. R. McCrae, 1992a). Half were instructed to fake good and half were given standard instructions. All completed the Interpersonal Adjective Scale--Revised, Big Five (J. S. Wiggins & P. D. Trapnell, 1997) under standard instructions, and their therapists completed the observer rating form of the NEO Five-Factor Inventory. A comparison group of 30 students completed the NEO PI-R under standard instructions. Standard and fake-good participants obtained significantly different NEO PI-R domain scores. Correlations between the NEO PI-R and criterion measures were significantly lower for faking than for standard patients. Validity scales for the NEO PI-R (J. A. Schinka, B. N. Kinder, & T. Kremer, 1997) were moderately accurate in discriminating faking from standard patients, but were only marginally accurate in discriminating faking patients from students.

  14. Spent fuel reprocessing past experience and future prospects

    International Nuclear Information System (INIS)

    Megy, J.

    1983-09-01

    A large experience has been gathered from the early fifties till now in the field of spent fuel reprocessing. As the main efforts in the world have been made for developping the reactors and the fuel fabrication industry to feed them, the spent fuel reprocessing activities came later and have not yet reached the industrial maturity existing to day for plants such as PWRs. But in the principal nuclear countries spent fuel reprocessing is to day considered as a necessity with two simultaneous targets: 1. Recovering the valuable materials, uranium and plutonium. 2. Conditionning the radioactive wastes to ensure safe definitive storage. The paper reviews the main steps: 1. Reprocessing for thermal reactor fuels: large plants are already operating or in construction, but in parallel a large effort of R and D is still under way for improvements. 2. The development of fast breeder plants implies associated fuel reprocessing facilities: pilot plants have demonstrated the closing of the cycle. The main difficulties encountered will be examined and particularly the importance of taking into account the problems of effluents processing and wastes storage [fr

  15. Produtos sanguíneos lábeis

    OpenAIRE

    Amaral, Soraia Necho

    2012-01-01

    O Instituto Português do Sangue (IPS) é o único organismo competente e responsável pela gestão da medicina transfusional a nível nacional. As suas funções compreendem: a coordenação de todas as atividades relacionadas com a transfusão de sangue, desde a colheita da dádiva à administração do componente sanguíneo; o planeamento do Sistema Nacional de Hemovigilância, certificando-se da segurança dos componentes sanguíneos disponíveis e distribuídos; e a garantia da continuidade dos seus serviços...

  16. Reliability of the NEO Five Factor Inventory short form for assessing personality after stroke.

    Science.gov (United States)

    Dwan, Toni; Ownsworth, Tamara; Donovan, Caroline; Lo, Ada Ho Yan

    2017-07-01

    It is well recognized that an individual's personality characteristics influence their psychological adjustment after stroke. However, there is a lack of research on the reliability of personality inventories for stroke. This study primarily aimed to evaluate the reliability of the Neuroticism, Extroversion, Openness to Experience (NEO)-Five Factor Inventory (NEO-FFI) for assessing pre-morbid personality and personality changes after stroke. Further aims were to investigate changes in personality during the hospital-to-home transition period and examine associations between personality and mood. Forty participants with stroke (52.5% male, M age=65.55 years) were recruited at time of hospital discharge and completed the NEO-FFI, Centre for Epidemiologic Studies - Depression and Geriatric Anxiety Inventory. Significant others completed an informant version of the NEO-FFI. Stroke participants were re-assessed on the NEO-FFI at 1-month and 4-months post-discharge. Forty matched controls also completed the NEO-FFI. Internal consistency was adequate for the NEO-FFI (α=0.57-0.86), although low for agreeableness. There was fair to excellent concordance between self-rated and informant versions of the NEO-FFI (ICC=0.58-0.78). Significant positive associations were found between neuroticism and mood (r=0.50-0.68), and significant negative associations were found between extraversion and mood (r=-0.33-0.36) and agreeableness and anxiety (r=-0.43). Self-ratings of stroke participants on the NEO-FFI at discharge did not significantly differ from matched controls. Extraversion levels significantly decreased, and agreeableness levels significantly increased between discharge and 1- and 4-months post-discharge. Overall, the results support the reliability of the NEO-FFI for assessing personality characteristics in the context of stroke.

  17. Topsy-Turvy Neo-Developmentalism: An Analysis of the Current Brazilian Model of Development

    Directory of Open Access Journals (Sweden)

    Bruno Milanez

    2015-09-01

    Full Text Available The paper discusses the similarities and differences between neo-developmentalism and neo-extractivism. The evaluation compares Brazil with nine other Latin American countries and is based on a framework that considers both economic policies and their outcomes. On the policy side, it looks at income, monetary, international trade, industrial and mineral resource policies; on the outcome side, it observes the composition of both exports and the Gross Domestic Product. In the end, we argue that neo-developmentalism and neo-extractivism are actually variations of the same development route and may face similar challenges in the long term.

  18. Neo-Liberalism in British Columbia Education and Teachers' Union Resistance

    Science.gov (United States)

    Poole, Wendy

    2007-01-01

    Since the election of the Campbell government in 2001, teachers have experienced heightened conflict with the provincial government. An analysis of the discourse and power relations between the BC Teachers' Federation (BCTF) and government reveals a neo-liberal agenda on the part of government and anti-neo-liberalism on the part of the BCTF.…

  19. Modelling of WWER-1000 fuel: state and prospects

    International Nuclear Information System (INIS)

    Medvedev, A.; Bibilashvili, Yu.; Bogatyr, S.; Khvostov, G.

    1994-01-01

    The role of START-3 code in studying and computerized modelling of post-irradiation behaviour of standard fuel rods in real operation conditions of WWER-1000 reactors is described. The models used in the code are based on experimental study of material properties, processes and post irradiation research on standard and experimental fuel pins. The code capability is verified by comparison with data from experiments on WWER test rods performed in MR reactor, the Russia-Finland tests SOFIT and the international program FUMEX. The comparison performed and the results thus obtained demonstrate the satisfactory ability of START-3 code to simulate fuel rod behaviour in normal operation condition. The calculations confirm the experimentally observed evidence of an essential margin on serviceability of WWER-1000 fuel pin with three year operation cycle permitting an increase in design fuel burnup. 2 tabs., 18 figs

  20. Modelling of WWER-1000 fuel: state and prospects

    Energy Technology Data Exchange (ETDEWEB)

    Medvedev, A; Bibilashvili, Yu; Bogatyr, S; Khvostov, G [Vsesoyuznyj Nauchno-Issledovatel` skij Inst. Neorganicheskikh Materialov, Moscow (Russian Federation)

    1994-12-31

    The role of START-3 code in studying and computerized modelling of post-irradiation behaviour of standard fuel rods in real operation conditions of WWER-1000 reactors is described. The models used in the code are based on experimental study of material properties, processes and post irradiation research on standard and experimental fuel pins. The code capability is verified by comparison with data from experiments on WWER test rods performed in MR reactor, the Russia-Finland tests SOFIT and the international program FUMEX. The comparison performed and the results thus obtained demonstrate the satisfactory ability of START-3 code to simulate fuel rod behaviour in normal operation condition. The calculations confirm the experimentally observed evidence of an essential margin on serviceability of WWER-1000 fuel pin with three year operation cycle permitting an increase in design fuel burnup. 2 tabs., 18 figs.

  1. Prospects for development of fuel cells

    Directory of Open Access Journals (Sweden)

    В. М. Шабер

    2017-10-01

    Full Text Available The article is devoted to the solution of a complex of problems that arise in small and medium-scale treatment complexes, gas production plants and small and medium-capacity power plants associated with the processing of crude methane and the possibility of reducing the greenhouse effect.The economic feasibility of the development of fuel cells (FC on raw biomethane was demonstrated by the authors in previous publications.The specificity of the solution of problems is focused on small and medium-scale treatment complexes, gas production plants and small and medium power plants.The aim of the study is to show the possibility of solving a multicomponent task of developing fuel cells, including the experimental determination of the actual use of sodium formate as a reducing agent for the production of electricity in a fuel cell (FC.Results are the following: the possibility of solving the issues of reducing greenhouse gas emissions into the atmosphere during processing of waste products of human vital activity is proved. A method for converting methane and carbon dioxide emissions into useful products is shown.

  2. The Mastodon in the room: how Darwinian is neo-Darwinism?

    Science.gov (United States)

    Brooks, Daniel R

    2011-03-01

    Failing to acknowledge substantial differences between Darwinism and neo-Darwinism impedes evolutionary biology. Darwin described evolution as the outcome of interactions between the nature of the organism and the nature of the conditions, each relatively autonomous but both historically and spatially intertwined. Furthermore, he postulated that the nature of the organism was more important than the nature of the conditions, leading to natural selection as an inevitable emergent product of biological systems. The neo-Darwinian tradition assumed a creative rather than selective view of natural selection, with the nature of the organism determined by the nature of the conditions, rendering the nature of the organism and temporal contingency unnecessary. Contemporary advances in biology, specifically the phylogenetics revolution and evo-devo, underscore the significance of history and the nature of the organism in biology. Darwinism explains more biology better, and better resolves apparent anomalies between living systems and more general natural laws, than does neo-Darwinism. The "extended" or "expanded" synthesis currently called for by neo-Darwinians is Darwinism. Copyright © 2010 Elsevier Ltd. All rights reserved.

  3. Neo4j essentials

    CERN Document Server

    Gupta, Sumit

    2015-01-01

    If you are an application developer or software architect who wants to dive into the Cypher language and learn the concepts of graph theory and graph-based data models, this is the book for you. Prior experience with a graph-based or NoSQL-based database is expected. Some knowledge of Java will be beneficial, as this will give you more insights into Neo4j's extensibility.

  4. Neo-patrimonialismo e populismo : uma leitura pela reciprocidade

    Directory of Open Access Journals (Sweden)

    Eric Sabourin

    2011-10-01

    Full Text Available Este artigo propõe uma leitura dos processos de neo-patrimonialismo em particular nos Estados africanos e de neo populismo nos Estados latino-americanos a luz da lógica de reciprocidade. Defende a hipótese que o principio de reciprocidade sendo diferente daquele da troca (e em particular da troca mercantil, ele pode gerar formas de alienação especificas e não redutíveis a principal forma de alienação do sistema de troca: a exploração capitalista analisada por Marx.

  5. A prospect of fast reactor and related fuel cycle in Japan

    Energy Technology Data Exchange (ETDEWEB)

    Nagata, Takashi [Japan Atomic Energy Agency, Ibaraki (Japan)

    2009-04-15

    JAEA has launched a new project 'Fast Reactor Cycle Technology Development'(FaCT) in cooperation with electric utilities. In this FaCT project, a combination of 'the Japanese sodium cooled loop type fast reactor with oxide fuel, the advanced aqueous reprocessing, and the simplified palletizing fuel fabrication systems' is adopted, where many innovative technologies with technical challenging issues are actively used in order to provide significant improvements in economic competitiveness, and enhancement of safety and reliability, sustainability, and nonproliferation. Fast reactor cycle technology will provide harmonic solutions for global issues of energy resources and environments, and is expected to contribute to sustainable development of the future society. Therefore, it was selected as one of key technologies of national importance in the third term (JPY2006-2010) 'Science and Technology Basic Plan' in March 2006 in Japan. The 'Nuclear Energy National Plan' in August 2006 states start up of a demonstration FR by around 2025 and deployment of a commercial FR before 2050, and start operating fuel cycle facilities when these reactors achieve consistency. Accordingly, we will decide about the adoption of innovative technologies by judging their applicability by 2010, and present the conceptual designs of commercial and demonstration FR cycle facilities by 2015 with the R and D plans to realize. In developing the FR cycle, 5 Party council, which consists of MEXt, MITI, electricity utilities, manufacturers, and JAEA, was established in July 2006 for moving forward on the commercialization smoothly. In this framework, users' requirements for the future R and D, a scenario of transition from light water reactor cycle to sodium cooled FR cycle, international collaboration, development schedule, demonstration steps, and so on are discussed. In this presentation, a prospect concerning the system design features of JSFR and a

  6. A prospect of fast reactor and related fuel cycle in Japan

    International Nuclear Information System (INIS)

    Nagata, Takashi

    2009-01-01

    JAEA has launched a new project 'Fast Reactor Cycle Technology Development'(FaCT) in cooperation with electric utilities. In this FaCT project, a combination of 'the Japanese sodium cooled loop type fast reactor with oxide fuel, the advanced aqueous reprocessing, and the simplified palletizing fuel fabrication systems' is adopted, where many innovative technologies with technical challenging issues are actively used in order to provide significant improvements in economic competitiveness, and enhancement of safety and reliability, sustainability, and nonproliferation. Fast reactor cycle technology will provide harmonic solutions for global issues of energy resources and environments, and is expected to contribute to sustainable development of the future society. Therefore, it was selected as one of key technologies of national importance in the third term (JPY2006-2010) 'Science and Technology Basic Plan' in March 2006 in Japan. The 'Nuclear Energy National Plan' in August 2006 states start up of a demonstration FR by around 2025 and deployment of a commercial FR before 2050, and start operating fuel cycle facilities when these reactors achieve consistency. Accordingly, we will decide about the adoption of innovative technologies by judging their applicability by 2010, and present the conceptual designs of commercial and demonstration FR cycle facilities by 2015 with the R and D plans to realize. In developing the FR cycle, 5 Party council, which consists of MEXt, MITI, electricity utilities, manufacturers, and JAEA, was established in July 2006 for moving forward on the commercialization smoothly. In this framework, users' requirements for the future R and D, a scenario of transition from light water reactor cycle to sodium cooled FR cycle, international collaboration, development schedule, demonstration steps, and so on are discussed. In this presentation, a prospect concerning the system design features of JSFR and a summary of the above R and D progresses for

  7. The DLR AsteroidFinder for NEOs

    Science.gov (United States)

    Mottola, Stefano; Kuehrt, Ekkehard; Michaelis, Harald; Hoffmann, Harald; Spietz, Peter; Jansen, Frank; Thimo Grundmann, Jan; Hahn, Gerhard; Montenegro, Sergio; Findlay, Ross; Boerner, Anko; Messina, Gabriele; Behnke, Thomas; Tschentscher, Matthias; Scheibe, Karsten; Mertens, Volker; Heidecke, Ansgar

    Potential Earth-impacting asteroids that spend most of their time interior to Earth's orbit are extremely difficult to be observed from the ground and remain largely undetected. Firstly, they are mostly located at small solar elongations, where the sky brightness and their faintness due to the large phase angle prevents their discovery. Secondly, these objects tend to have very long synodic orbital periods, which makes observation opportunities rare and impact warning times short. Because of these limitations, even the advent of next generation ground-based asteroid surveys is not likely to radically improve the situation (Veres et al. Icarus 203, p472, 2009). On the other hand, a small satellite with a suitable design can observe close to the Sun and detect these objects efficiently against a dark sky background. For this reason, DLR, the German Aerospace Center, has selected AsteroidFinder as the first experiment to be launched under its new compact satellite national program. The primary goal of the mission is to detect and characterize Near Earth Objects (NEOs), with a particular focus on the population of objects completely contained within Earth's orbit (IEOs or Inner Earth Objects). Current dynamical models predict the existence of more than 1000 such objects down to a size of 100m, of which, due to the abovementioned observation difficulties, only 10 have been discovered to date. Benefitting from the vantage point of a Low Earth Orbit (LEO), AsteroidFinder makes use of a small optical telescope to scan those regions of the sky that are close to the Sun, and therefore beyond the reach of ground based observatories. By estimating the population, the size and the orbital distribution of IEOs, AsteroidFinder will contribute to our knowledge of the inner Solar System, and to the assessment of the impact hazard for the Earth. A secondary goal of the mission is to demonstrate techniques that enable the space-based detection of space debris in the cm size range

  8. Career guidance for Social Justice in Neo-Liberal Times

    DEFF Research Database (Denmark)

    Thomsen, Rie; Skovhus, Randi Boelskifte; Sultana, Ronald

    SIMPOSIO 16. Career guidance for Social Justice in Neo-Liberal Times (English) Ronald Sultana (Coord.), Tristram Hooley (Coord.), Rie Thomsen, Peter Plant, Roger Kjærgård, Marcelo Afonso Ribeiro, Randi Boelskifte Skovhus and Tron Inglar......SIMPOSIO 16. Career guidance for Social Justice in Neo-Liberal Times (English) Ronald Sultana (Coord.), Tristram Hooley (Coord.), Rie Thomsen, Peter Plant, Roger Kjærgård, Marcelo Afonso Ribeiro, Randi Boelskifte Skovhus and Tron Inglar...

  9. Carcinoma espinocelular infiltrante de base de cráneo en paciente de 16 años con albinismo óculo-cutáneo

    Directory of Open Access Journals (Sweden)

    J.M. Lasso-Vázquez

    2013-12-01

    Full Text Available Presentamos el caso de una adolescente africana de 16 años de edad afectada por albinismo óculo-cutáneo, que desarrolló un carcinoma epidermoide en pabellón auricular derecho que requirió escisión radical y reconstrucción con colgajo TRAM libre. El albinismo es un trastorno metabólico genético que consiste en la incapacidad hereditaria para sintetizar melanina. Tiene dos variantes clínicas: el albinismo ocular y el albinismo óculo-cutáneo. En determinados países africanos, los pacientes afectos por esta enfermedad son socialmente rechazados y por ello no se les presta un control sanitario adecuado. Por esta razón el tumor llevaba varios años de evolución y cuando la paciente fue vista en nuestro centro, existía una infiltración profunda con afectación severa de la base del cráneo. La compleja anatomía de las estructuras vitales en esta región hace que la resección quirúrgica de los tumores sea complicada. Comentamos las peculiaridades en la reconstrucción de casos complejos en la base lateral del cráneo con proyección a la zona temporal.

  10. Bulk Densities of Binary Asteroids from the Warm Spitzer NEO Survey

    NARCIS (Netherlands)

    Kistler, John; Trilling, D. E.; Mueller, M.; Hora, J. L.; Harris, A. W.; Bhattacharya, B.; Bottke, W. F.; Chesley, S.; Emery, J. P.; Fazo, G.; Mainzer, A.; Penprase, B.; Smith, H. A.; Spahr, T. B.; Stansberry, J. A.; Thomas, C. A.

    2010-01-01

    The Warm Spitzer NEO survey, ExploreNEOs, will observe approximately 700 Near Earth Asteroids. Several of these objects are known to be binary asteroid systems. Binary systems are interesting due to the unique opportunity they present for determining the masses and densities of their constituent

  11. Creationism, Neo-Darwinism and Panspermia

    Science.gov (United States)

    Klyce, Brig; Wickramasinghe, N. Chandra

    2011-10-01

    Creationists and neo-Darwinists have spent the past several decades engaged in a sullen trench warfare, occasionally firing at each other with little effect. We argue in this article that an acceptance of panspermia as a "third way" might lead to a long over-due reconciliation between the contending groups.

  12. Visible photometry of NEOs in support of a Warm Spitzer program

    Science.gov (United States)

    Trilling, David E.; Jones, Sarah; Penprase, Bryan; Emery, Josh; Harris, Alan; Spahr, Tim; Delbo, Marco

    2009-08-01

    Near Earth Objects (NEOs) may act as dynamical and compositional tracers of the history of near-Earth space. However, despite their scientific importance, key characteristics of the NEO population -- such as the size distribution, mix of albedos and mineralogies, and contributions from so-called dead or dormant comets -- remain largely unexplored; some 99% of all presently known NEOs are essentially uncharacterized. We have been awarded 500 hours of Warm Spitzer time to study some 700 NEOs. The Spitzer data will allow us to measure thermal fluxes and, in combination with optical data, derive albedos and diameters for a large fraction of all known NEOs. Remarkably, the primary uncertainty in our Spitzer results will derive from a lack of good optical photometry for our targets. Fortunately, our targets are generally bright, and obtaining good V band measurements of them requires only a modest amount of time on modest aperture telescopes. We propose here for 36 hours of SMARTS 1.3-m time or 54 hours of SMARTS 0.9-m time to obtain visible photometry of the 72 southern moderately bright ``B'' semester targets in our Warm Spitzer program. These program is ideal for queue/service observing because each observation requires only ~30 minutes and our targets are all over the sky.

  13. Rapid neo-sex chromosome evolution and incipient speciation in a major forest pest.

    Science.gov (United States)

    Bracewell, Ryan R; Bentz, Barbara J; Sullivan, Brian T; Good, Jeffrey M

    2017-11-17

    Genome evolution is predicted to be rapid following the establishment of new (neo) sex chromosomes, but it is not known if neo-sex chromosome evolution plays an important role in speciation. Here we combine extensive crossing experiments with population and functional genomic data to examine neo-XY chromosome evolution and incipient speciation in the mountain pine beetle. We find a broad continuum of intrinsic incompatibilities in hybrid males that increase in strength with geographic distance between reproductively isolated populations. This striking progression of reproductive isolation is coupled with extensive gene specialization, natural selection, and elevated genetic differentiation on both sex chromosomes. Closely related populations isolated by hybrid male sterility also show fixation of alternative neo-Y haplotypes that differ in structure and male-specific gene content. Our results suggest that neo-sex chromosome evolution can drive rapid functional divergence between closely related populations irrespective of ecological drivers of divergence.

  14. Population Policies and Education: Exploring the Contradictions of Neo-Liberal Globalisation

    Science.gov (United States)

    Bovill, Catherine; Leppard, Margaret

    2006-01-01

    The world is increasingly characterised by profound income, health and social inequalities (Appadurai, 2000). In recent decades development initiatives aimed at reducing these inequalities have been situated in a context of increasing globalisation with a dominant neo-liberal economic orthodoxy. This paper argues that neo-liberal globalisation…

  15. Present status and prospect of spent fuel transportation

    International Nuclear Information System (INIS)

    Adachi, H.

    1987-01-01

    Problems linked with spent fuel transportation in Japan, where there are 35 NPPs in operation, are considered. Every year about 500 t U are shipped to fuel reprocessing plants in Japan, as well as in France and UK. Four kinds of casks: HZ, EXCELLOX, TN and TK - are used for this purpose. By the mid-1990's it is suggested to build in Japan fuel reprocessing plant with capacity of 800 t U per year

  16. An Example of Neo-Tarekat in Bandung, Indonesia

    Directory of Open Access Journals (Sweden)

    Muhammad Adlin Sila

    2009-08-01

    Full Text Available At present, several tarekats surfaced in the urban centers of Indonesia and continued to perform as a vehicle of social and cultural cohesion. The emergence of these so-called neo-tarekats (neo-sufi mystical orders introduced rational reference to the sacred texts and Islamic law and rejected the close association between tarekats and the veneration of saints and holy places as generally known as silsilah in the old version of tarekats. This article depicts a close look at of Tarekat Kadisiyyah, an example of the neo-tarekats, located in central Bandung city of West Java. Most of the followers of this tarekat come from young and educated among urban people in Bandung. Mursyid (Ar: murshid of this tarekat refers to a person named Suprapto Kadis, who experienced the absence of an outward mursyid (lahiriah, but received direct guidance from Allah. There is no chain of transmission of mystical knowledge from a special mursyid to him. This kind of mursyid reminds us the concept of uwaysiyah in classical Islamic literature. Uways is the person who knew the prophet Muhammad but never met him in person. Another concept can be used to analyzes this phenomena is the notions of khidr functioning as an invisible guide for the mursyid. Tarekat Kadisiyyah trained its students that one should become his own self in order to know Allah. In doing this, Tarekat Kadisiyyah concluded that shari>‘ah is important as it is the vehicle to gain closeness to Allah. Keywords: Tarekat Kadisiyah, Suprapto Kadis, neo-tarekat, mursyid, suluk

  17. Neo-Timm staining in the thalamus of chronically epileptic rats

    Directory of Open Access Journals (Sweden)

    Hamani C.

    2005-01-01

    Full Text Available The thalamus is an important modulator of seizures and is severely affected in cholinergic models of epilepsy. In the present study, chronically epileptic rats had their brains processed for neo-Timm and acetylcholinesterase two months after the induction of status epilepticus with pilocarpine. Both controls and pilocarpine-treated animals presented neo-Timm staining in the anterodorsal nucleus, laterodorsal nucleus, reticular nucleus, most intralaminar nuclei, nucleus reuniens, and rhomboid nucleus of the thalamus, as well as in the zona incerta. The intensity of neo-Timm staining was similar in control and pilocarpine-treated rats, except for the nucleus reuniens and the rhomboid nucleus, which had a lower intensity of staining in the epileptic group. In animal models of temporal lobe epilepsy, zinc seems to modulate glutamate release and to decrease seizure activity. In this context, a reduction of neo-Timm-stained terminals in the midline thalamus could ultimately result in an increased excitatory activity, not only within its related nuclei, but also in anatomical structures that receive their efferent connections. This might contribute to the pathological substrate observed in chronic pilocarpine-treated epileptic animals.

  18. Job Prospects for Metallurgical Engineering.

    Science.gov (United States)

    Basta, Nicholas

    1985-01-01

    Job prospects in mining, metal-extraction, steel, and refining industries are depressed, but technological discoveries are opening up new fields for metallurgical engineers. Enrollment/employment opportunities and salaries in these areas are discussed a well as the roles of foreign competition, plastics applications, and ceramics research and…

  19. The DUPIC fuel development program in KAERI

    Energy Technology Data Exchange (ETDEWEB)

    Yang, M S; Park, H S [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1997-07-01

    This study describes the DUPIC fuel development program in KAERI as follows; Burning spent PWR fuel again in CANDU by DUPIC, Compatibility with existing CANDU system, Feasibility of DUPIC fuel fabrication, Waste reduction, Safeguard ability, Economics of DUPIC fuel cycle, The DUPIC fuel development program, and International prospective. 5 refs., 10 figs.

  20. Pedagogy of the Consumer: The Politics of Neo-Liberal Welfare Reform

    Science.gov (United States)

    Wilkins, Andrew

    2012-01-01

    Situated against the backdrop of a widespread and growing interest in the linkages between neo-liberalism and welfare, this paper introduces the lens of neo-liberalism as a conceptual strategy for thinking about contemporary issues in education policy. Through charting the historic rise of unfettered market institutions and practices in the…

  1. Education Policy as Proto-Fascism: The Aesthetics of Racial Neo-Liberalism

    Science.gov (United States)

    Webb, P. Taylor; Gulson, Kalervo N.

    2011-01-01

    We argue that neo-liberal educational policy has emerged as a proto-fascist governmentality. This contemporary technology relies on State racisms and racial orderings manifested from earlier liberal and neo-liberal practices of biopower. As a proto-fascist technology, education policy, and school choice policies in particular, operate within a…

  2. Spent fuel management in Japan - Facts and prospects

    International Nuclear Information System (INIS)

    Nagano, K.

    2002-01-01

    This paper discusses recent developments and future issues related to spent fuel management in Japan. With increasing pressure of spent fuel discharge from the power plants in operation and, in contrast, uncertainties in their processing and management services, spent fuel storage in short and medium terms has been receiving the highest priority in nuclear policy discussions in Japan. While small-scale interim storage devices, as well as capacity expansion (re-racking, etc.) and shared uses of existing devices, are introduced at number of power stations, large scale AFR (away from reactor) 'Storage of Recycle Fuel Resources' is expected to come in a medium and long-run. Commercial operation of 'Storage of Recycle Fuel Resources' is allowed its way, as the bill of amendment to the law for regulation of nuclear power reactors and other nuclear-related activities has passed in the Diet. In the meantime, the Atomic Energy Commission has launched working group discussions for revision of 'The Long-term Program of Research, Development and Utilization of Nuclear Energy' to be completed in 2000. This revision is hoped to set up a stage of national debate of nuclear policy, which might lead to fill conceptual gaps between bodies promoting nuclear development and general public. The author's attempt to illustrate the role of storage in spent fuel management is also presented from a theoretical point of view. (author)

  3. Highlights of 50 years of nuclear fuels developments

    International Nuclear Information System (INIS)

    Simnad, M.T.

    1989-01-01

    The development of nuclear fuels since the discovery of nuclear fission is briefly surveyed in this paper. The fabrication of the uranium fuel for the first nuclear pile, CP-1, is described. The research and development studies and fabrication of the different types of nuclear fuels for the variety of research and power reactors are reviewed. The important factors involved to achieve low fuel cycle costs and reliable performance in the fuel elements are discussed in the historical context

  4. Germline stem cells and neo-oogenesis in the adult human ovary.

    Science.gov (United States)

    Liu, Yifei; Wu, Chao; Lyu, Qifeng; Yang, Dongzi; Albertini, David F; Keefe, David L; Liu, Lin

    2007-06-01

    It remains unclear whether neo-oogenesis occurs in postnatal ovaries of mammals, based on studies in mice. We thought to test whether adult human ovaries contain germline stem cells (GSCs) and undergo neo-oogenesis. Rather than using genetic manipulation which is unethical in humans, we took the approach of analyzing the expression of meiotic marker genes and genes for germ cell proliferation, which are required for neo-oogenesis, in adult human ovaries covering an age range from 28 to 53 years old, compared to testis and fetal ovaries served as positive controls. We show that active meiosis, neo-oogenesis and GSCs are unlikely to exist in normal, adult, human ovaries. No early meiotic-specific or oogenesis-associated mRNAs for SPO11, PRDM9, SCP1, TERT and NOBOX were detectable in adult human ovaries using RT-PCR, compared to fetal ovary and adult testis controls. These findings are further corroborated by the absence of early meiocytes and proliferating germ cells in adult human ovarian cortex probed with markers for meiosis (SCP3), oogonium (OCT3/4, c-KIT), and cell cycle progression (Ki-67, PCNA), in contrast to fetal ovary controls. If postnatal oogenesis is confirmed in mice, then this species would represent an exception to the rule that neo-oogenesis does not occur in adults.

  5. Status and prospects for spent fuel management in France

    International Nuclear Information System (INIS)

    Portal, R.; L'Epine, P. de

    1996-01-01

    The spent fuel arisings and storage capacities, the interface between fuel storage and transportation activities, the spent fuel storage technology, the reprocessing and recycling industrial activities in France are described in the paper. (author). 6 figs, 8 tabs

  6. Housing transformations Buenos Aires Metropolitan Area. The passage from Neo-liberalism to Urban Neo-development

    Directory of Open Access Journals (Sweden)

    Juan Pablo del Río

    2014-12-01

    Full Text Available The economic recovery that followed the 2001/02 crisis in Argentina came with a relevant improvement in a number of social and economic indicators, related among other reasons to the design of public policies aimed at recuperating employment levels and the productive matrix. In this context, the “construction – public works” tandem became a central topic in the agenda, and Real Estate expansion was widely assessed as a positive outcome by macro-economic standards. However, this process was not exempt of contradictions, as can be seen in the metropolitan area of Buenos Aires, where it is possible to observe a set of concurring tendencies resulting from the hybridization of the urban neo-liberalization still present and the recent expansion of urban neo-developmentalism. As a result, the expansion of State-led de-commodification of goods and services aimed at social reproduction, coexists with a persisting process of socially regressive housing space production, together with an intense commodification of existing housing, associated with a growing financializationof “bricks”.

  7. 1986 POLICY: BEGINNING OF NEO-LIBERAL AGENDA

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics... VIOLATED THE CONSTITUTIONAL PRINCIPLES OF. EQUALITY & SOCIAL JUSTICE.. INTRODUCED A SOCIO-POLITICAL FAULT FOR NEO-LIBERAL FORCES TO PROMOTE PRINCIPLE OF PARALLEL STREAMS.

  8. Performance Evaluation of Solid Oxide Fuel Cell by Computer ...

    African Journals Online (AJOL)

    The search for sustainable energy source that can compete with the existing one led to the discovery and acceptance of fuel cell technologies as a perfect replacement for fossil fuel. The ability of Solid Oxide Fuel Cells (SOFC) to capture the heat generation during the process of energy generation from electrochemical ...

  9. New prospects in low cost nuclear fuel cycles

    International Nuclear Information System (INIS)

    Lewis, W.B.

    1978-01-01

    The economics of various fuel cycles for the CANDU reactor are considered. It is argued, political considerations apart, that recycling plutonium was never likely to be particularly profitable, and rising costs have made it less so. On the other hand, a strong case is made for irradiating pure thorium fuel in a CANDU reactor containing driver fuel with 1.81% enrichment, and then recycling 233 U without any admixture of 238 U or Pu. The economics are particularly favourable if an organic-cooled reactor is used. (N.D.H.)

  10. September 11, Neo-liberalism and Discourse

    DEFF Research Database (Denmark)

    Holmgreen, Lise-Lotte

    2006-01-01

    of British financial news reports is analysed. This corpus covers the two-month period before and after the September-11 attacks and illustrates the extent to which economic ideology (neo-liberalism) and socio-economic change (the terrorist attacks) influence the choice of metaphor, and hence...

  11. Neo-Mercantilist Policy and China’s Rise as a Global Power

    Directory of Open Access Journals (Sweden)

    Fu-Lai Tony Yu

    2017-12-01

    Full Text Available This paper argues that China is adopting Neo-mercantilist policies in its national development and global expansion. China’s Neo-mercantilist strategies include promoting nationalism and patriotism, stockpiling gold and foreign reserves, striving for favorable balance of payment via exchange rate manipulation, tariff, export subsidies and other trade protections. The Chinese government also controls population growth for national development and social control, initiates “Belt and Road” project and the Asian Infrastructure Investment Bank to counter American and Western influences, and deploys strategic expansion in Africa, South Asia and Latin American countries. China’s economic success through Neo-mercantilist strategies may provide an incentive for other Asian developing nations such as the Philippines to follow.

  12. Highlights of 50 years of nuclear fuel development

    International Nuclear Information System (INIS)

    Simnad, M.T.

    1989-01-01

    The development of nuclear fuels since the discovery of nuclear fission is briefly surveyed in this paper. The fabrication of the uranium fuel for the first nuclear pile, CP-1, is described. The research and development studies and fabrication of the different types of nuclear fuels for the variety of research and power reactors are reviewed. The important factors involved to achieve low fuel-cycle costs and reliable performance in the fuel elements are discussed in the historical context. 10 refs

  13. Una registrazione neo-sumerica di orzo da Nippur

    Directory of Open Access Journals (Sweden)

    di Pasquale, Emanuella

    2003-06-01

    Full Text Available This article presents the edition of a Neo-Sumerian cuneiform text from Nippur. The tablet records a balanced account of barley distributed to several people under the supervision of Lu-Enlila, and is dated to the sixth month of Shu-Suen's fifth year

    El artículo presenta la edición de un texto cuneiforme de época neo-sumeria procedente de la ciudad de Nippur. La tablilla registra un balance contable de asignaciones de cebada a diversos individuos, bajo la responsabilidad de Lu-Enlila. El documento está datado en el sexto mes del año 5 de reinado de Shu-Suen.

  14. Low-Pt-Content Anode Catalyst for Direct Methanol Fuel Cells

    Science.gov (United States)

    Narayanan, Sekharipuram; Whitacre, Jay

    2008-01-01

    Combinatorial experiments have led to the discovery that a nanophase alloy of Pt, Ru, Ni, and Zr is effective as an anode catalyst material for direct methanol fuel cells. This discovery has practical significance in that the electronic current densities achievable by use of this alloy are comparable or larger than those obtained by use of prior Pt/Ru catalyst alloys containing greater amounts of Pt. Heretofore, the high cost of Pt has impeded the commercialization of direct methanol fuel cells. By making it possible to obtain a given level of performance at reduced Pt content (and, hence, lower cost), the discovery may lead to reduction of the economic impediment to commercialization.

  15. pSv3neo transfection and radiosensitivity of human cancer cell lines

    International Nuclear Information System (INIS)

    Parris, C.N.; Masters, J.R.W.; Green, M.H.L.

    1990-01-01

    Immortalisation of human fibroblasts by transfection with a plasmid, pSV3neo, results in an increase in their radioresistance. The change in radiosensitivity may either be a consequence of transformation or due to expression of the SV40 T-antigen in pSV3neo. To investigate these two possibilities, we transfected pSV3neo into cells already transformed and immortalised. The radiosensitivies of three human bladder cancer cell lines were unaltered in clones expressing T-antigen, indicating that the changes observed in fibroblasts probably are a consequence of transformation, and not the presence of SV40 T-antigen. (author)

  16. Neo4j graph data modeling

    CERN Document Server

    Lal, Mahesh

    2015-01-01

    If you are a developer who wants to understand the fundamentals of modeling data in Neo4j and how it can be used to model full-fledged applications, then this book is for you. Some understanding of domain modeling may be advantageous but is not essential.

  17. Recent prospects of MOX fuel and strategy about nuclear fuel cycle

    International Nuclear Information System (INIS)

    Liu Dingqin

    1991-04-01

    It is clearly described what is the preliminary adequate strategic concern for different nuclear power countries under different nuclear power development conditions. It is also stressed on the basic situation of the design technology, manufacture technology, operation experiences and quantitative economic analysis for MOX fuel application since fast breed reactor commercialization has been delayed. The author specially proposed that in a short term China should adopt an intermediate storage strategy matched with the construction of a pilot reprocessing plant to prepare the technical basis for commercialized reprocessing plant later on and to follow the development of MOX fuel technology

  18. Calibrating the social value of prospective new goods: The case of hydrogen fuel cell electric Vehicles

    Science.gov (United States)

    Topel, Robert H.

    2018-01-01

    Economic studies of the value of a new good or product innovation are typically retrospective: after a new good has been developed and marketed to consumers, data on prices and consumer choices can be used to estimate welfare gains. This paper calibrates the prospective welfare gains in the United States from a nascent vehicle platform, fuel cell electric vehicles (FCVs), that may or may not succeed in competition with existing vehicle platforms. Prospective gains are due to three main sources: (1) possibly reduced carbon emissions compared to existing vehicle alternatives; (2) the monopsony benefit to the U.S. from reducing world oil demand and hence the price of oil; (3) national security benefits due to reduced "oil dependence", mitigating the impact of oil price shocks on national income. I find that the benefits of reduced carbon emissions are likely to be quite small because reduced oil demand in the U.S. as only a small impact on world oil consumption and carbon emissions. Net monopsony benefits to U.S. consumers are much larger.

  19. A state of limbo: the politics of waiting in neo-liberal Latvia.

    Science.gov (United States)

    Ozoliņa-Fitzgerald, Liene

    2016-09-01

    This article presents an ethnographic study of politics of waiting in a post-Soviet context. While activation has been explored in sociological and anthropological literature as a neo-liberal governmental technology and its application in post-socialist context has also been compellingly documented, waiting as a political artefact has only recently been receiving increased scholarly attention. Drawing on ethnographic fieldwork at a state-run unemployment office in Riga, this article shows how, alongside activation, state welfare policies also produce passivity and waiting. Engaging with the small but developing field of sociological literature on the politics of waiting, I argue that, rather than interpreting it as a clash between 'neo-liberal' and 'Soviet' regimes, we should understand the double-move of activation and imposition of waiting as a key mechanism of neo-liberal biopolitics. This article thus extends the existing theorizations of the temporal politics of neo-liberalism. © London School of Economics and Political Science 2016.

  20. Arte contemporáneo: temporalidad, territorialización y circulación

    Directory of Open Access Journals (Sweden)

    Jonathan Feldman

    2017-01-01

    Full Text Available Este artículo da cuenta de diferentes definiciones teóricas del arte contemporáneo y sus características, recurriendo a los enfoques de Giorgio Agamben, Terry Smith, Boris Groys y Julieta Aranda, para, a continuación, poner en relación estas posiciones con la noción de territorialización esbozada por Deleuze y Guattari (1985, y así posar la mirada sobre tres niveles de territorialidad que atraviesan las definiciones de arte contemporáneo: local, regional y global. Esto permite, finalmente, vincular estos niveles a los modos de circulación y exhibición del arte contemporáneo para generar discursos sostenidos sobre la base de las instituciones y los mercados artísticos. Se hace también una breve descripción de los casos de dos instituciones porteñas que permiten comprobar estos niveles de territorialidad y las formas de circulación del arte contemporáneo.

  1. [The relationship between acupuncture-moxibustion theory of DOU Hanqing and Neo- Confucianism].

    Science.gov (United States)

    Li, Baojin; Huang, Longxiang

    2018-02-12

    For the construction factors of acupuncture-moxibustion theory of DOU Hanqing , a doctor in Jin-Yuan Dynasty, we studied his life, acupuncture-moxibustion theory and culture background in the History of Medicine and Philosophy of Science & Technology. It was found that the major source of DOU Hanqing ' s Confucianism was the CHENG - ZHU Neo-Confucianism. The data show that Neo-Confucianism played an important role in the enrichment of his human nature, spirit, moral cultivation and political talent, making him a scholar in the Jin - Yuan dynasty, also shaping his medical ethics, medical skill and acupuncture-moxibustion theory. The inheritance, development and application of CHENG - ZHU Neo-Confucianism provided the most fundamental thinking, research methods and patterns for DOU Hanqing to interpret the acupuncture classics, summarize his teachers' experience and develop his theoretical system. DOU Hanqing ' s acupuncture-moxibustion practice and theory reached a new level, because he took acupuncture-moxibustion as one of the knowledge investigation and attainment of CHENG - ZHU Neo-Confucianism.

  2. The nuclear fuel cycle

    International Nuclear Information System (INIS)

    1998-05-01

    After a short introduction about nuclear power in the world, fission physics and the French nuclear power plants, this brochure describes in a digest way the different steps of the nuclear fuel cycle: uranium prospecting, mining activity, processing of uranium ores and production of uranium concentrates (yellow cake), uranium chemistry (conversion of the yellow cake into uranium hexafluoride), fabrication of nuclear fuels, use of fuels, reprocessing of spent fuels (uranium, plutonium and fission products), recycling of energetic materials, and storage of radioactive wastes. (J.S.)

  3. MELOX fuel fabrication plant: Operational feedback and future prospects

    International Nuclear Information System (INIS)

    Hugelmann, D.; Greneche, D.

    2000-01-01

    As of December 1, 1998, 32 Europeans LWRs are loaded with MOX fuel. It clearly means that plutonium recycling in MOX fuels is a mature industry, with successful operational experience in fabrication plants in some European countries, especially in France. Indeed, the recycling of plutonium generated in LWRs is one of the objectives of the full Reprocessing-Conditioning-Recycling (RCR) strategy chosen by France in the 70's. The most impressive results of this strategy, is the fact that 31 of the 32 reactors are loaded with MOX fuels supplied by the COGEMA Group from the same efficient fabrication process, the MIMAS process, improved for the MELOX plant to become the A-MIMAS process. In France, 17 reactors are already loaded and 11 additional reactors are technically suited to do so. Indeed, the EDF MOX program plans to use MOX in 28 of its 57 reactors. An EDF 900 MWe reactor core contains 157 assemblies of 264 rods each. 52 fuel assemblies per year are necessary for a 'UO 2 3-batches-MOX 3-batches' core management. In this case, a third of the UO 2 and a third of the MOX assemblies are replaced yearly, that means 36 UO 2 fuel assemblies and 16 MOX fuel assemblies. Some MOX fuelled reactors have now switched from the previously described core management to a so-called 'hybrid core management'. In this case, a quarter of UO 2 assemblies is replaced yearly. The first EDF reactor loaded with MOX fuel was Saint-Laurent B1, in 1987. The in-core experience, based on several hundred assemblies loaded, with reloading on a 1/3 cycle basis, shows that there is no operational difference between UO 2 and MOX fuels, both in terms of performance and safety. MOX fueling of 900 MWe EDF's PWRs, with a limited in-core MOX ratio of 30%, has needed only minor adaptations, such as addition of control rods, modification of the boron concentration in the cooling system and precaution against radiation exposure, easy to set up (optimisation of the fresh MOX fuel handling process, remote

  4. SCIENCE WHERE CULTURE MATTERS: A NEO-CLASSICAL ...

    Indian Academy of Sciences (India)

    SCIENCE WHERE CULTURE MATTERS: A NEO-CLASSICAL APPROACH TO EXPLORE UNTAPPED BACTERIAL DIVERSITY. MILIND WATVE; Dept of Microbiology, Abasaheb Garware College, Pune. www.culturematters.org; * Life Research Foundation, Pune; * Evolvus Biotech Pvt. Ltd.,Pune ...

  5. Strategy and Economic Prospect of Back-end Cycle through ATW

    International Nuclear Information System (INIS)

    Hendri Firman Windarto; Siti Alimah

    2003-01-01

    Strategy and economic prospect of back-end cycle through ATW has been studied. Nuclear fuel cycle through ATW is a single stratum of back-end cycle. By ATW, volume of spent fuel which should be disposed in long term can be reduced from 70,000 MHTM to 3,000 MHTM and half-life of spent fuel can be reduced from 15,700,000 years to 300 years. Strategic values of the ATW cycle are to prevent proliferation risk and to reduce the uncertainty of long term dispose. Economic prospect of the ATW cycle will give some advantages on reducing of spent fuel volume and its disposal period, and producing electricity. (author)

  6. Human integration as a fundamental anthropological problem in Neo-Humanistic education / Song-Guk Joh

    OpenAIRE

    Joh, Song-Guk

    1997-01-01

    Neo-Humanistic education (or "humanistic education" in Neo-Humanist terms) is an irrationalistic educational movement which developed in the USA during the 1960s and 1970s on the basis of Progressivism, Existentialism, Humanistic Psychology, Romantic criticism and some religious movements. Neo-Humanistic Education attempts to effect human integration as the most important goal in the context of education. This research focuses on human integration as a fundamental anthropological problem i...

  7. A prospective analysis of Brazilian biofuel economy: Land use, infrastructure development and fuel pricing policies

    Science.gov (United States)

    Nunez Amortegui, Hector Mauricio

    Being the two largest ethanol producers in the world, transportation fuel policies in Brazil and the U.S. affect not only their domestic markets but also the global food and biofuel economy. Hence, the complex biofuel policy climate in these countries leaves the public with unclear conclusions about the prospects for supply and trade of agricultural commodities and biofuels. In this dissertation I develop a price endogenous mathematical programming model to simulate and analyze the impacts of biofuel policies in Brazil and the U.S. on land use in these countries, agricultural commodity and transportation fuel markets, trade, and global environment. The model maximizes the social surplus represented by the sum of producers' and consumers' surpluses, including selected agricultural commodity markets and fuel markets in the U.S., Brazil, Argentina, China, and the Rest-of-the-World (ROW), subject to resource limitations, material balances, technical constraints, and policy restrictions. Consumers' surplus is derived from consumption of agricultural commodities and transportation fuels by vehicles that generate vehicle-kilometers-traveled (VKT). While in the other regional components aggregate supply and demand functions are assumed for the commodities included in the analysis, the agricultural supply component is regionally disaggregated for Brazil and the U.S., and the transportation fuel sector is regionally disaggregated for Brazil. The U.S. agricultural supply component includes production of fourteen major food/feed crops, including soybeans, corn and wheat, and cellulosic biofuel feedstocks. The Brazil component includes eight major annual crops, including soybeans, corn, wheat, and rice, and sugarcane as the energy crop. A particular emphasis is given to the beef-cattle production in Brazil and the potential for livestock semi-intensification in Brazilian pasture grazing systems as a prospective pathway for releasing new croplands. In the fuel sector of both

  8. Neo-liberalism, Crisis and the Contradictions of Depoliticisation

    Directory of Open Access Journals (Sweden)

    Peter Burnham

    2017-10-01

    Full Text Available This paper develops a political economy analysis of depoliticisation in the context of the crisis of neo-liberalism in Western Europe. Following a discussion of the theoretical foundations of the concept, it emphases that whilst depoliticisation strategies are often associated with neo-liberalism, such strategies have a longer trajectory existing even within Keynesian regimes. The paper then details the many forms taken by depoliticisation within neo-liberal governing regimes focusing on the reorganisation of civil society and the state from the late 1970s to the present primarily with examples from the UK. It suggests, contrary to much popular discussion, that there is a significant degree of continuity in the form of economic manage-ment followed before, during and after the recent financial crisis of 2008/09. Both in terms of ideology and practice, many governments have maintained and even deepened their commitment to depoliticised gov-erning principles. However it seems clear that attempts to depoliticise neo-liberal economic policy have not enabled state managers to avoid the emergence of crisis at the level of the state. Contrary to accounts which argue in simplistic fashion that `economic’ crisis produces `political’ crisis, this paper suggests that crisis is best understood as expressed simultaneously in both economic and political forms. Crisis at the level of the state precipitated in part by the entrenchment of depoliticised governing strategies is not simply the result of economic crisis but is an aspect of that crisis contributing to its depth and apparent insolubility. In this way the paper challenges some critiques of depoliticisation which have suggested (Hay 2014, 303 that the concept is in part both fatalistic and functionalist removing much of the political contingency of the moment of crisis itself.

  9. China's spent fuel treatment: The present status and prospects

    International Nuclear Information System (INIS)

    Jiang Yunqing

    1999-01-01

    In the mid 1980s, China launched the development of nuclear power dominated by PWRs and opted for the closed fuel cycle strategy. On the basis of irradiated fuel reprocessing for defence purpose, an R and D programme for civil reprocessing has been implemented. Currently, China's spent fuel arising is limited but its amount will sharply increase with nuclear power expansion early next century. Spent fuel stored at reactor site for at least 5 years will be transported either by a combination of sea and rail or by road directly to the Lanzhou Nuclear Fuel Complex. A wet centralized storage facility with a 550 tHM capacity has been built for interim storage of spent fuel. Also, a multi-purpose reprocessing pilot plant with a maximum throughput of 400 kg HM/d is now under construction and will be put into commissioning by the turn of the century. A large-scale commercial reprocessing plant, perhaps with a capacity of 800 tHM/a, will be set up around 2020. Recovered uranium and plutonium from reprocessing will go to a demonstration plant and be manufactured into MOX fuel for FBR and PWR. The defence radwaste from reprocessing is at present being conditioned into the proper forms and will be disposed in appropriate repositories. All expertise and experience gained from these practices will be utilized in the future civil radwaste management. (author)

  10. International conference on Asian nuclear prospects 2010

    International Nuclear Information System (INIS)

    2010-10-01

    The proceedings of the second international conference on Asian nuclear prospects was held during October 10-13, 2010. The topics covered were atomic minerals exploration, fuels and fuel fabrication, fast reactor engineering and technology, thermal reactors, fuel reprocessing, materials development, nuclear instrumentation and electronics, reactor and environmental safety, waste management, knowledge management and HRD. Papers relevant to INIS are indexed separately

  11. Uncovering the evolutionary history of neo-XY sex chromosomes in the grasshopper Ronderosia bergii (Orthoptera, Melanoplinae) through satellite DNA analysis.

    Science.gov (United States)

    Palacios-Gimenez, Octavio M; Milani, Diogo; Lemos, Bernardo; Castillo, Elio R; Martí, Dardo A; Ramos, Erica; Martins, Cesar; Cabral-de-Mello, Diogo C

    2018-01-08

    Neo-sex chromosome systems arose independently multiple times in evolution, presenting the remarkable characteristic of repetitive DNAs accumulation. Among grasshoppers, occurrence of neo-XY was repeatedly noticed in Melanoplinae. Here we analyzed the most abundant tandem repeats of R. bergii (2n = 22, neo-XY♂) using deep Illumina sequencing and graph-based clustering in order to address the neo-sex chromosomes evolution. The analyses revealed ten families of satDNAs comprising about ~1% of the male genome, which occupied mainly C-positive regions of autosomes. Regarding the sex chromosomes, satDNAs were recorded within centromeric or interstitial regions of the neo-X chromosome and four satDNAs occurred in the neo-Y, two of them being exclusive (Rber248 and Rber299). Using a combination of probes we uncovered five well-defined cytological variants for neo-Y, originated by multiple paracentric inversions and satDNA amplification, besides fragmented neo-Y. These neo-Y variants were distinct in frequency between embryos and adult males. The genomic data together with cytogenetic mapping enabled us to better understand the neo-sex chromosome dynamics in grasshoppers, reinforcing differentiation of neo-X and neo-Y and revealing the occurrence of multiple additional rearrangements involved in the neo-Y evolution of R. bergii. We discussed the possible causes that led to differences in frequency for the neo-Y variants between embryos and adults. Finally we hypothesize about the role of DNA satellites in R. bergii as well as putative historical events involved in the evolution of the R. bergii neo-XY.

  12. Neo-liberal economic practices and population health: a cross-national analysis, 1980-2004.

    Science.gov (United States)

    Tracy, Melissa; Kruk, Margaret E; Harper, Christine; Galea, Sandro

    2010-04-01

    Although there has been substantial debate and research concerning the economic impact of neo-liberal practices, there is a paucity of research about the potential relation between neo-liberal economic practices and population health. We assessed the extent to which neo-liberal policies and practices are associated with population health at the national level. We collected data on 119 countries between 1980 and 2004. We measured neo-liberalism using the Fraser Institute's Economic Freedom of the World (EFW) Index, which gives an overall score as well as a score for each of five different aspects of neo-liberal economic practices: (1) size of government, (2) legal structure and security of property rights, (3) access to sound money, (4) freedom to exchange with foreigners and (5) regulation of credit, labor and business. Our measure of population health was under-five mortality. We controlled for potential mediators (income distribution, social capital and openness of political institutions) and confounders (female literacy, total population, rural population, fertility, gross domestic product per capita and time period). In longitudinal multivariable analyses, we found that the EFW index did not have an effect on child mortality but that two of its components: improved security of property rights and access to sound money were associated with lower under-five mortality (p = 0.017 and p = 0.024, respectively). When stratifying the countries by level of income, less regulation of credit, labor and business was associated with lower under-five mortality in high-income countries (p = 0.001). None of the EFW components were significantly associated with under-five mortality in low-income countries. This analysis suggests that the concept of 'neo-liberalism' is not a monolithic entity in its relation to health and that some 'neo-liberal' policies are consistent with improved population health. Further work is needed to corroborate or refute these findings.

  13. From Protectionism to Neo-Protectionism: New Dimensions of Liberal Regulation

    Directory of Open Access Journals (Sweden)

    Panchenko Volodymyr

    2017-12-01

    Full Text Available The article summarizes the main concepts of the policy of protectionism. It was proved that the shaded or semi-open nature of protectionism of the 21st century model does not fall under classical manifestations of protectionism recorded in the WTO documents, and therefore further hybridization of its forms actualizes the need for their classification in order to attract the attention of the scientific community to new challenges to the global regulation of the system of international economic relations. It was discovered, that protectionism in the process of economical globalization has evolved from trade policy based on introduction of tariff limitations, and later from non-tariff protection instruments, into a complex comprehensive state mechanism for increasing competitiveness of the national economy in the process of globalization, which we call neo-protectionism. Was provided a classification of neo-protectionism and were singled out forms of manifestation of each of its types. Were established country features of neo-protectionism policy. Was established that flexibility of tools for implementing neo-protectionism policy, absence of a unified approach to interpreting the methods of achieving goals announced by the state, differences in priorities and unity of the goals of all instruments, which are to stimulate restoration of economic growth, can be considered as determinative signs of new regulation. It was found that state intervention becomes an inherent characteristic of liberal politics. Was observed that neo-protectionism with its flexible instruments becomes a policy of reducing asymmetric distribution of benefits from globalization and reaction to global imbalances, which again emphasizes the thesis that state participation in regulation of economic processes is an objective reality, and we are witnessing transformation of the previously announced trend towards deregulation into re-regulation.

  14. Korea prospects

    International Nuclear Information System (INIS)

    Wyman, V.

    1990-01-01

    Contacts between the South Korean nuclear industry and a combined United Kingdom mission representing AEA Technology and British Nuclear Fuels Limited (BNFL) are reported. Prospects for entering the Korean market in two areas are perceived. The first is waste management and the second is the Safe Integral Reactor (SIR), an advanced pressurized water reactor design. AEA Technology and three collaborators have been promoting SIR as an inherently safe reactor design. Korean interest could be expressed in financial backing for the building of SIR stations in Korea and the opportunity could arise for BNFL to win fuel supply contracts. (UK)

  15. Nuclear fuel for WWER reactors. Current status and prospects

    International Nuclear Information System (INIS)

    Molchanov, V.

    2006-01-01

    In this paper the following results from the JSC TVEL post-irradiation studies of full-scale fuel assemblies are discussed: 1) Oxide layer on fuel rod (FR) cladding does not exceed 15 μm; 2) Fission Gas Release does not exceed 3%; 3) Satisfactory condition of cladding. Concerning the operating experience it is noticed that: 1) Design criteria are fulfilled; 2) 5 TVSA are stayed at Kalinin-1 for 6 years up to burnup of 59 MWxdays/kgU; 3) 12 working assemblies (WA) are operated at Kola-3 for 6 years up to burnup of 57 MWxdays/kgU. At the end the following conclusions are made: 1) The main task of further development of nuclear fuel for WWER-1000 reactors is the increasing fuel rod burnup up to 72 MWxdays/kgU and operating life up to 6 years through the increase in uranium load in FA and maximum use of potential built-in in the designs of TVSA and TVS-2; 2) In the nearest future R and D in the field of nuclear fuel for WWER will be directed at justification of maneuvering fuel characteristics as well as at introducing of optimized zirconium alloys

  16. Framing the Real: Lefèbvre and NeoRealist Cinematic Space as Practice

    OpenAIRE

    Brancaleone, David

    2014-01-01

    In 1945 Roberto Rossellini's Neo-realist Rome, Open City set in motion an approach to cinema and its representation of real life – and by extension real spaces – that was to have international significance in film theory and practice. However, the re-use of the real spaces of the city, and elsewhere, as film sets in Neo-realist film offered (and offers) more than an influential aesthetic and set of cinematic theories. Through Neo-realism, it can be argued that we gain access to a cinematic re...

  17. Current and prospective fuel test programmes in the MIR reactor

    Energy Technology Data Exchange (ETDEWEB)

    Izhutov, A.L.; Burukin, A.V.; Iljenko, S.A.; Ovchinnikov, V.A.; Shulimov, V.N.; Smirnov, V.P. [State Scientific Centre of Russia Research Institute of Atomic Reactors, Ulyanovsk region (Russian Federation)

    2007-07-01

    MIR reactor is a heterogeneous thermal reactor with a moderator and a reflector made of metal beryllium, it has a channel-type design and is placed in a water pool. MIR reactor is mainly designed for testing fragments of fuel elements and fuel assemblies (FA) of different nuclear power reactor types under normal (stationary and transient) operating conditions as well as emergency situations. At present six test loop facilities are being operated (2 PWR loops, 2 BWR loops and 2 steam coolant loops). The majority of current fuel tests is conducted for improving and upgrading the Russian PWR fuel, these tests involve issues such as: -) long term tests of short-size rods with different modifications of cladding materials and fuel pellets; -) further irradiation of power plant re-fabricated and full-size fuel rods up to achieving 80 MW*d/kg U; -) experiments with leaking fuel rods at different burnups and under transient conditions; -) continuation of the RAMP type experiments at high burnup of fuel; and -) in-pile tests with simulation of LOCA and RIA type accidents. Testing of the LEU (low enrichment uranium) research reactor fuel is conducted within the framework of the RERTR programme. Upgrading of the gas cooled and steam cooled loop facilities is scheduled for testing the HTGR fuel and sub-critical water-cooled reactor, correspondingly. The present paper describes the major programs of the WWER high burn-up fuel behavior study in the MIR reactor, capabilities of the applied techniques and some results of the performed irradiation tests. (authors)

  18. Preclinical Characterization of a Novel Monoclonal Antibody NEO-201 for the Treatment of Human Carcinomas

    Directory of Open Access Journals (Sweden)

    Massimo Fantini

    2018-01-01

    Full Text Available NEO-201 is a novel humanized IgG1 monoclonal antibody that was derived from an immunogenic preparation of tumor-associated antigens from pooled allogeneic colon tumor tissue extracts. It was found to react against a variety of cultured human carcinoma cell lines and was highly reactive against the majority of tumor tissues from many different carcinomas, including colon, pancreatic, stomach, lung, and breast cancers. NEO-201 also exhibited tumor specificity, as the majority of normal tissues were not recognized by this antibody. Functional assays revealed that treatment with NEO-201 is capable of mediating both antibody-dependent cellular cytotoxicity (ADCC and complement-dependent cytotoxicity (CDC against tumor cells. Furthermore, the growth of human pancreatic xenograft tumors in vivo was largely attenuated by treatment with NEO-201 both alone and in combination with human peripheral blood mononuclear cells as an effector cell source for ADCC. In vivo biodistribution studies in human tumor xenograft-bearing mice revealed that NEO-201 preferentially accumulates in the tumor but not organ tissue. Finally, a single-dose toxicity study in non-human primates demonstrated safety and tolerability of NEO-201, as a transient decrease in circulating neutrophils was the only related adverse effect observed. These findings indicate that NEO-201 warrants clinical testing as both a novel diagnostic and therapeutic agent for the treatment of a broad variety of carcinomas.

  19. Nuevos Baremos para la Adaptación Española del Inventario de Personalidad NEO Revisado (NEO PI-R: Fiabilidad y Datos Normativos en Voluntarios de la Población General

    Directory of Open Access Journals (Sweden)

    Jesús Sanz

    2009-01-01

    Full Text Available La adaptación española comercial del Inventario de Personalidad NEO-Revisado (NEO PI-R fue baremada en contextos de selección de personal. Aunque estos baremos son apropiados cuando las personas pueden distorsionar sus respuestas, no lo son para situaciones con deseabilidad social baja como, por ejemplo, investigaciones con voluntarios, precisamente el contexto donde se desarrolló y baremó el NEO PI-R original. Se presentan por primera vez datos normativos y de fiabilidad de la adaptación española comercial del NEO PI-R obtenidos con voluntarios de la población general española (N = 682. Los índices de consistencia interna de las escalas globales del NEO PI-R fueron excelentes (alfas ≥ 0,85, mientras que en 25 de las 30 escalas específicas oscilaron entre adecuados y buenos (alfas ≥ 0,60 y < 0,80. Las diferencias estandarizadas en las puntuaciones del NEO PI-R entre la muestra de voluntarios y la de selección de personal de los baremos comerciales alcanzaron medias absolutas de tamaño medio (d = 0,53, lo que justifica la creación de baremos específicos para situaciones donde las personas no tienen interés directo en distorsionar sus respuestas. Se ofrecen baremos separados para mujeres y varones voluntarios, y se discute su utilidad en diferentes contextos de evaluación de la personalidad (p. ej., contextos clínicos.

  20. Transnational pharmaceutical corporations and neo-liberal business ethics in India.

    Science.gov (United States)

    D'Mello, Bernard

    2002-03-01

    The author critiques the expedient application of market valuation principles by the transnational corporations and other large firms in the Indian pharmaceutical industry on a number of issues like patents, pricing, irrational drugs, clinical trials, etc. He contends that ethics in business is chiseled and etched within the confines of particular social structures of accumulation. An ascendant neo-liberal social structure of accumulation has basically shaped these firms' sharp opposition to the Indian Patents Act, 1970, government administered pricing, etc. The author contents that the practice of neo-liberal economics is strongly associated with a "one-dimensional" ethics that privileges market valuation principles over all others. This seems to inevitably generate a social counter-movement that struggles for social protections. He critiques neo-liberal business practices from a perspective that derives from the work of the economic anthropologist Karl Polanyi. Before the present phase of liberalization in India, markets were "managed", but without a "welfare state" in place. Moving toward deregulation of the markets without a welfare state in place is unethical. Keeping the debilities of the institutional framework of public policy in mind, the author adopts a Polanyian perspective that places its trust and hope in the growing social legitimacy of the counter-movement in opposition to both neo-liberal business practices and the degenerate behavior of state agencies.

  1. Republicanismo neo-romano e democracia contestatória

    Directory of Open Access Journals (Sweden)

    Ricardo Silva

    2011-06-01

    Full Text Available O artigo examina o conceito de democracia derivado da fórmula "neo-romana" da liberdade como não-dominação. Para os autores vinculados à tradição neo-romana, a realização do princípio republicano do povo como "guardião da liberdade" depende da constituição de um modelo de democracia contestatória, apresentado como superação dos modelos da democracia eleitoral e da democracia participativa - ambos considerados tributários de uma concepção positiva de liberdade. Após deter-se no exame do conceito de democracia contestatória, o artigo analisa as principais críticas a esse conceito. Duas objeções recebem destaque: a de que o racionalismo do modelo contestatório conduz à despolitização da deliberação democrática e a de que o excessivo zelo dos neo-romanos contra o populismo e a tirania da maioria reproduz os traços "elitistas" da tradição republicana clássica. Conclui-se com uma breve avaliação da pertinência dessas críticas.

  2. Experimental evidence of oxygen thermo-migration in PWR UO{sub 2} fuels during power ramps using in-situ oxido-reduction indicators

    Energy Technology Data Exchange (ETDEWEB)

    Riglet-Martial, Ch., E-mail: chantal.martial@cea.fr; Sercombe, J.; Lamontagne, J.; Noirot, J.; Roure, I.; Blay, T.; Desgranges, L.

    2016-11-15

    The present study describes the in-situ electrochemical modifications which affect irradiated PWR UO{sub 2} fuels in the course of a power ramp, by means of in-situ oxido-reduction indicators such as chromium or neo-formed chemical phases. It is shown that irradiated fuels (of nominal stoichiometry close to 2.000) under temperature gradient such as that occurring during high power transients are submitted to strong oxido-reduction perturbations, owing to radial migration of oxygen from the hot center to the cold periphery of the pellet. The oxygen redistribution, similar to that encountered in Sodium Fast Reactors fuels, induces a massive reduction/precipitation of the fission products Mo, Ru, Tc and Cr (if present) in the high temperature pellet section and the formation of highly oxidized neo-formed grey phases of U{sub 4}O{sub 9} type in its cold section, of lower temperature. The parameters governing the oxidation states of UO{sub 2} fuels under power ramps are finally debated from a cross-analysis of our results and other published information. The potential chemical benefits brought by oxido-reductive additives in UO{sub 2} fuel such as chromium oxide, in connection with their oxygen buffering properties, are discussed.

  3. Spent fuel management in China: Current status and prospects

    International Nuclear Information System (INIS)

    Zhu, J.L.

    1998-01-01

    In this paper, the development of nuclear power in China, its status of operating nuclear power plants and progress of on-going NPP projects are described. With the arising of spent fuel from NPPs, a national policy of a closed nuclear fuel cycle has been determined. Following storage at reactor sites for at least 5 years (generally maximum 10 years), spent fuel will be transferred to an away-from-reactor pool type centralized storage facility. Adjacent to the storage facility, a multi-purpose reprocessing pilot plant will be set up by the end of this century. An industrial scale reprocessing plant would be succeeded around the year 2020. China's spent fuel management activities include at-reactor storage, transportation, away-from-reactor storage and reprocessing. Relatively detailed description of the work done up to now on spent fuel management and plans for the future are described. It should be noted that activities related to the management of high level radioactive waste are not included here. (author)

  4. Nuclear fuel manufacturing. Current activities and prospects at INR Pitesti

    International Nuclear Information System (INIS)

    Horhoianu, Grigore

    2001-01-01

    Development of the CANDU nuclear fuel is currently conducted world wide onto two principal directions: - increasing the service span of the current type of fuel and improving the efficiency of burnup in reactor; - reducing the costs of fuel manufacturing by improving the design and manufacturing technologies in condition of increasing fuel performance. In parallel, a research program, RAAN, is undergoing, concerning the development of advanced CANDU type fuels (SEU, RU, DUPIC, Th), aiming at reducing the overall costs per fuel cycle. In the INR TRIGA reactor a large number of experimental fuel elements manufactured in INR were irradiated under different conditions specific to the CANDU reactor operation. Post irradiation investigations both destructive and non-destructive were carried out in the hot cells at INR Pitesti. The experimental results were used in order to optimize and evaluate the fuel project, to check the fuel manufacturing technologies as well as to certify the computational codes. The local thermo-mechanical analyses by final element methods, modelling the SCC phenomenon, probabilistic evaluation of performance parameters of the fuel, constitute new directions in the modelling and developing computational code. The developed codes were submitted to a thorough validation process to comply with the quality assurance. The excellent results obtained in INR were confirmed by participation in the FUMEX International Exercises of computer code intercomparison, organized by IAEA Vienna. Progress was also recorded in establishing the behaviour of fuel elements failed during reactor operation and the effect their maintenance in the reactor core could have upon the power reactor operation. A system-expert variant was worked out able for a short term analysis of the decisions referring to removing the failing element at Cernavoda NPP. As advanced CANDU fuel is concerned, until now preliminary variants for a fuel bundle with 43 elements containing slightly

  5. A Cognitive Adopted Framework for IoT Big-Data Management and Knowledge Discovery Prospective

    OpenAIRE

    Mishra, Nilamadhab; Lin, Chung-Chih; Chang, Hsien-Tsung

    2015-01-01

    In future IoT big-data management and knowledge discovery for large scale industrial automation application, the importance of industrial internet is increasing day by day. Several diversified technologies such as IoT (Internet of Things), computational intelligence, machine type communication, big-data, and sensor technology can be incorporated together to improve the data management and knowledge discovery efficiency of large scale automation applications. So in this work, we need to propos...

  6. Current status and future prospects for enabling chemistry technology in the drug discovery process.

    Science.gov (United States)

    Djuric, Stevan W; Hutchins, Charles W; Talaty, Nari N

    2016-01-01

    This review covers recent advances in the implementation of enabling chemistry technologies into the drug discovery process. Areas covered include parallel synthesis chemistry, high-throughput experimentation, automated synthesis and purification methods, flow chemistry methodology including photochemistry, electrochemistry, and the handling of "dangerous" reagents. Also featured are advances in the "computer-assisted drug design" area and the expanding application of novel mass spectrometry-based techniques to a wide range of drug discovery activities.

  7. Neo-No-Barroco o barrococó: Hacia una perspectiva menos inexacta del neobarroco

    Directory of Open Access Journals (Sweden)

    Eduardo Espina

    2015-05-01

    Full Text Available Este ensayo analiza las nociones estéticas principales que definen la llamada poética neobarroca. Al respecto, presenta elementos para justificar la utilización de los vocablos neo-no-barroco y barrococó en vez de “neobarroco”, por considerar a este término erróneo, pues proyecta la idea –por el uso del prefijo– que es descendiente directo del barroco español, algo que es una verdad incompleta. La relación del neo-no-barroco/barrococó con la idea fundacional del Romanticismo, de que la poesía debe pensar sobre el pensamiento, es obvia y sin embargo no ha sido debidamente analizada. Por lo tanto, al haber una reconfiguración etimológica de la estética asociada con la dificultad y la superposición de escollos retóricos que le exigen al acto de la lectura una mayor concentración, la poética neo-no-barroca o barrococó podrá alcanzar una más exacta definición y permitirá incluir voces poéticas hasta ahora no consideradas neobarrocas. This essay reflects upon the principal aesthetic notions that define the so-called Neobaroque poetic. In this regard, new evidence is presented in order to justify the use of two words (synonymous, neo-no-barroco and barrococó instead of “Neo-baroque”, considering this term a misnomer since it projects the idea –by the use of the prefix– that it is a direct descendent of the Spanish Baroque, which is an incomplete truth. The relationship of the neo-no-barroco / barrococó with the foundational idea of Romanticism; that poetry should think about thinking is obvious and yet, it has not been adequately analyzed. Therefore, having an etymological reconfiguration of the aesthetic associated with difficulty and with the overlapping rhetorical pitfalls that demand the act of reading at a higher concentration level, the neo-no-barroco or barrococó poetic will be able to reach a more precise definition and allow the inclusion of poetic voices hitherto unconsidered as Neobaroque.

  8. Status and prospects for gas cooled reactor fuels. Proceedings of two IAEA meetings held in June 2004 and June 2005

    International Nuclear Information System (INIS)

    2009-04-01

    Recently, efforts to develop high temperature gas cooled reactors with an aim to building futuristic nuclear energy systems with advanced nuclear fuel cycles in the context of the Generation IV International Forum have increased significantly. In addition, several development projects are ongoing, focusing on the burning of weapons grade plutonium, including civil plutonium and other transuranic elements using the 'deep-burn concept', or 'inert matrix fuels', especially in the form of coated particles in gas cooled reactor systems. There is also considerable global interest in developing 'nuclear hydrogen' energy systems using high temperature gas cooled reactors. Apart from these developments, the value of preserving the large technology base developed in Germany, the United Kingdom and the United States of America, as well as information developed in other countries, has also been a subject of interest to the IAEA. At the second annual meeting of the 'technical working group on nuclear fuel cycles options and spent fuel management' (TWG-NFCO), held in Vienna from 28-30 May 2003, it was recommended to hold a technical meeting on Current Status and Future Prospects of Gas Cooled Reactor Fuels. The meeting should cover the technological progress that has been made in the last three years and plan future fabrication and qualification facilities for GCR/HTR fuel. TWG-NFCO considered it timely that this progress should be presented and discussed in the interested community. Recognizing the numerous activities being pursued in many Member States, the IAEA convened the technical meeting on this topic in June 2004 in Vienna. Consequently, an update meeting was held in June 2005, which was hosted by the Kharkov Institute of Physics and Technology of Ukraine to review and integrate the latest developments. This publication combines the results of the technical meeting of June 2004 and the meeting of June 2005. The proceedings presented here contain 25 in depth papers on the

  9. Neo-Industrial and Sustainable Development of Russia as Mineral Resources Exploiting Country

    Science.gov (United States)

    Prokudina, Marina; Zhironkina, Olga; Kalinina, Oksana; Gasanov, Magerram; Agafonov, Felix

    2017-11-01

    In the Russian economy, the world leadership in the extraction of different mineral resources is combined with the potential for their processing and a significant scientific sector. Innovative development of raw materials extraction is impossible without the parallel technological modernization of the high-tech sector. In general, the complex of these processes is a neo-industrialization of the economy. Neo-industrially oriented transformation of the economy reflects complex changes in its structure, the transformation of established stable relationships between various elements of the system of social production that determine macroeconomic proportions. Neo-industrial transformations come along with the modification of economic relations associated with investments, innovations, labor and income distribution, with the process of locating productive forces and regulating the economy by the government. Neo-industrialization of economy is not only significant changes in its technological and reproductive structure (the development of high-tech industries, the integration of science and industry), but, above all, the implementation of a system structural policy of innovative development of raw material industry and the recovery of manufacturing industries on a new technological basis.

  10. Chemogenomic discovery of allosteric antagonists at the GPRC6A receptor

    DEFF Research Database (Denmark)

    Gloriam, David E.; Wellendorph, Petrine; Johansen, Lars Dan

    2011-01-01

    and pharmacological character: (1) chemogenomic lead identification through the first, to our knowledge, ligand inference between two different GPCR families, Families A and C; and (2) the discovery of the most selective GPRC6A allosteric antagonists discovered to date. The unprecedented inference of...... pharmacological activity across GPCR families provides proof-of-concept for in silico approaches against Family C targets based on Family A templates, greatly expanding the prospects of successful drug design and discovery. The antagonists were tested against a panel of seven Family A and C G protein-coupled receptors...

  11. A methodology for assessing the market benefits of alternative motor fuels: The Alternative Fuels Trade Model

    Energy Technology Data Exchange (ETDEWEB)

    Leiby, P.N.

    1993-09-01

    This report describes a modeling methodology for examining the prospective economic benefits of displacing motor gasoline use by alternative fuels. The approach is based on the Alternative Fuels Trade Model (AFTM). AFTM development was undertaken by the US Department of Energy (DOE) as part of a longer term study of alternative fuels issues. The AFTM is intended to assist with evaluating how alternative fuels may be promoted effectively, and what the consequences of substantial alternative fuels use might be. Such an evaluation of policies and consequences of an alternative fuels program is being undertaken by DOE as required by Section 502(b) of the Energy Policy Act of 1992. Interest in alternative fuels is based on the prospective economic, environmental and energy security benefits from the substitution of these fuels for conventional transportation fuels. The transportation sector is heavily dependent on oil. Increased oil use implies increased petroleum imports, with much of the increase coming from OPEC countries. Conversely, displacement of gasoline has the potential to reduce US petroleum imports, thereby reducing reliance on OPEC oil and possibly weakening OPEC`s ability to extract monopoly profits. The magnitude of US petroleum import reduction, the attendant fuel price changes, and the resulting US benefits, depend upon the nature of oil-gas substitution and the supply and demand behavior of other world regions. The methodology applies an integrated model of fuel market interactions to characterize these effects.

  12. Neo-Philanthropy

    DEFF Research Database (Denmark)

    Villadsen, Kaspar

    2011-01-01

    -governmental organisations and specific services run by volunteers to help different target groups. Charitable trusts may offer philanthropic aid for diverse purposes which allegedly supersede the state’s capacity for action, such as the promotion of business ethics, the strengthening of community participation, health......Neo-philanthropy refers to the re-emergence of philanthropic activities and a growing public trust in those who carry them out as ameliorators of societal and social issues. The original term ‘philanthropy’ designates the donating of money or services for societal purposes or for the benefit...... of specific groups with some perceived need. Further, it is understood that philanthropic activities are guided by some kind of moral, religious, or humanitarian principles. The term has a rather broad range of applications, since it may both designate funding bodies that offer charitable donations and non...

  13. Centralized disassembly and packaging of spent fuel in the DOE spent fuel management system

    International Nuclear Information System (INIS)

    Johnson, E.R.

    1986-01-01

    In October 1984, E.R. Johnson Associates, Inc. (JAI) initiated a study of the prospective use of a centralized facility for the disassembly and packaging of spent fuel to support the various elements of the US Dept. of Energy (DOE) spent fuel management system, including facilities for monitored retrievable storage (MRS) and repositories. It was DOE's original plan to receive spent fuel at each repository where it would be disassembled and packaged (overpacked) for disposal purposes. Subsequently, DOE considered the prospective use of MRS of spent fuel as an option for providing safe and reliable management of spent fuel. This study was designed to consider possible advantages of the use of centralized facilities for disassembly and packaging of spent fuel at whose location storage facilities could be added as required. The study was divided into three principal technical tasks that covered: (a) development of requirements and criteria for the central disassembly and packaging facility and associated systems. (2) Development of conceptual designs for the central disassembly and packaging facility and associated systems. (3) Estimation of capital and operating costs involved for all system facilities and determination of life cycle costs for various scenarios of operation - for comparison with the reference system

  14. Current status and future prospects for enabling chemistry technology in the drug discovery process

    Science.gov (United States)

    Djuric, Stevan W.; Hutchins, Charles W.; Talaty, Nari N.

    2016-01-01

    This review covers recent advances in the implementation of enabling chemistry technologies into the drug discovery process. Areas covered include parallel synthesis chemistry, high-throughput experimentation, automated synthesis and purification methods, flow chemistry methodology including photochemistry, electrochemistry, and the handling of “dangerous” reagents. Also featured are advances in the “computer-assisted drug design” area and the expanding application of novel mass spectrometry-based techniques to a wide range of drug discovery activities. PMID:27781094

  15. New discoveries in Upper and Middle Magdalena

    International Nuclear Information System (INIS)

    Carta Petrolera

    1998-01-01

    In six association contracts and one risk participation contract may give Colombia the possibility of finding new oil reserves. These prospects, located in the Upper and Middle Magdalena Valleys and the Eastern Plains. the completion process, evaluation, confirmation and commercialization should be in the next two years, these new discoveries also reveal interesting geological aspects; some in fractured limestone, similar to the found at Maracaibo lake in Venezuela, where vast oil fields were discovered

  16. Spent fuel management in Hungary: Current status and prospects

    International Nuclear Information System (INIS)

    Ferenczi, G.

    1996-01-01

    The Paks Nuclear Power Plant Ltd. operates the only NPP of Hungary, consisting of a 4 WWER-440 type units. Since 1989, approximately 40-50 % of the total yearly electricity generation of the country has been supplied by this plant. The fresh fuel is imported from Russia (previously from the Soviet Union) and the spent fuel assemblies are shipped back to Russia for later reprocessing after 5 years of decay storage in the spent fuel pools of the plant. Seeing the political and economical changes that started in Russia, the Paks NPP's management made a decision in 1990 to study the implementation of an independent spent fuel storage facility (ISFSF) at the Paks site and in 1992 to choose the GEC-ALSTHOM's MVDS. On the basis of the Construction License issued by the HAEC, the construction of the ISFSF was started in March 1995. The paper gives general information on the spent fuel arisings, the storage at the site, the shipment to Russia and on the implementation of the ISFSF. (author). 3 refs

  17. Dilatation and Dysfunction of the Neo-aortic Root and in 76 Patients After the Ross Procedure.

    Science.gov (United States)

    Zimmermann, Corina A; Weber, Roland; Greutmann, Matthias; Dave, Hitendu; Müller, Christoph; Prêtre, René; Seifert, Burkhardt; Buechel, Emanuela Valsangiacomo; Kretschmar, Oliver; Attenhofer Jost, Christine H

    2016-08-01

    Pulmonary autograft replacement (Ross procedure) is used as an alternative to prosthetic aortic valve replacement patients with aortic valve disease. There are limited data on incidence and risk factors for dilatation and dysfunction of the neo-aortic after the Ross procedure. Ross procedure was performed in 100 patients at our institution between 1993 and 2011. In 76 patients, complete follow-up data were available. Their median age at surgery was 16 (0.4-58) years (76 % males; 95 % with congenital aortic valve disease). Median follow-up duration was 5.2 years (0.3-16.0 years). We analyzed their clinical and echocardiographic follow-up to identify possible risk factors for neo-aortic root dilatation and dysfunction. Ross procedure included reduction plasty of the native ascending aorta in 25 % of patients. During follow-up, 21 patients (28 %) developed neo-aortic root dilatation, 38 patients (50 %) dilatation oft the native ascending aorta and 7 patients (9 %) at least moderate neo-aortic regurgitation. Univariate risk factors for neo-aortic root dilatation were preoperative aortic regurgitation (p = 0.04), concomitant reduction plasty of the ascending aorta (p = 0.009) and a longer duration of follow-up (p = 0.005). Younger age at surgery was associated with dilatation of the ascending aorta (p = 0.03). Reoperation on the neo-aortic root because of severe dilatation was necessary in 6 patients (8 %), where 2 patients had at least moderate neo-aortic root regurgitation. Neo-aortic root and aortic dilatation are common after the Ross procedure. This is often combined with neo-aortic valve dysfunction. Close follow-up of these patients is mandatory.

  18. Comprehensive primary health care under neo-liberalism in Australia.

    Science.gov (United States)

    Baum, Fran; Freeman, Toby; Sanders, David; Labonté, Ronald; Lawless, Angela; Javanparast, Sara

    2016-11-01

    This paper applies a critical analysis of the impact of neo-liberal driven management reform to examine changes in Australian primary health care (PHC) services over five years. The implementation of comprehensive approaches to primary health care (PHC) in seven services: five state-managed and two non-government organisations (NGOs) was tracked from 2009 to 2014. Two questions are addressed: 1) How did the ability of Australian PHC services to implement comprehensive PHC change over the period 2009-2014? 2) To what extent is the ability of the PHC services to implement comprehensive PHC shaped by neo-liberal health sector reform processes? The study reports on detailed tracking and observations of the changes and in-depth interviews with 63 health service managers and practitioners, and regional and central health executives. The documented changes were: in the state-managed services (although not the NGOs) less comprehensive service coverage and more focus on clinical services and integration with hospitals and much less development activity including community development, advocacy, intersectoral collaboration and attention to the social determinants. These changes were found to be associated with practices typical of neo-liberal health sector reform: considerable uncertainty, more directive managerial control, budget reductions and competitive tendering and an emphasis on outputs rather than health outcomes. We conclude that a focus on clinical service provision, while highly compatible with neo-liberal reforms, will not on its own produce the shifts in population disease patterns that would be required to reduce demand for health services and promote health. Comprehensive PHC is much better suited to that task. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  19. Informações preliminares sobre flebotomíneos do norte do Paraná

    Directory of Open Access Journals (Sweden)

    Ueslei Teodoro

    2006-04-01

    Full Text Available São relatados os resultados de coletas de flebotomíneos feitas em localidades de 10 municípios do Estado do Paraná, com armadilhas de Falcão em domicílios, abrigos de animais domésticos e nas matas, de 1999 a 2002. Coletaram-se 13.653 flebotomíneos de 10 espécies dos gêneros Brumptomyia, Expapillata, Evandromyia, Migonemyia, Pintomyia, Nyssomyia, Psathyromyia. A espécie Nyssomyia neivai predominou em cinco municípios, e N. whitmani nos demais, a qual foi numericamente superior à primeira. Verificou-se maior freqüência de flebotomíneos nas matas, residências, pocilgas e galinheiros. As investigações sobre a participação de animais domésticos e da fauna de flebotomíneos na epidemiologia da leishmaniose tegumentar deveriam fazer parte da rotina dos serviços de saúde, especialmente nas áreas onde a doença é endêmica.

  20. Status and prospects of fuel cell technology in Europe

    International Nuclear Information System (INIS)

    Van Dijkum

    1998-01-01

    Fuel Cells attract a lot of press attention today and an some example of a recent press heading is: ''Orders for Onsi's fuel cells hit $111 million''. The principle of fuel cell technology is explained and examples of realized applications given. In short: fuel cells can be used everywhere where power (and heat) is needed. Regarding the status of fuel cells, Europe is way behind Japan and the US. The 15 PAFC-200 kWe units in operation in Europe (worldwide > 90 units) produced 46,796 MWhe during 296,704 cumulative operating hours with an availability % over 70.00. The world record on continuous operation is held by Japan with 9,478 hours reached at 14th September 1996 and two PAFC-units passed their 40,000 hours of cumulative operation (US and Japan). In Japan, market enabling support is continued with subsidies of one third of the costs for 7 PAFC-units. In the Netherlands, Energy Distribution Companies test their tubular 100 kWe SOFC-unit. During 1,335 hours of continuous operation, the unit produced 165 MWhe in total at 3rd March. EnergieNed, CLC/Ansaldo and Gastec evaluated changes for co-generation and small power production with packaged fuel cell power plants in EU and EFTA countries. In general the authors concluded that implementation of fuel cell power plants in all EU and EFTA countries will be probably possible with today' s technical regulations. On might wonder: What has fuel cell technology to offer in one of the most efficient and low-priced gas economies in Europe, the Netherlands. An example of efficient energy use are greenhouses with artificial lighting and CO 2 -fertilization and energy (heat) storage device. Applying relatively favorable depreciation periods and (utility) interest rate, a PAFC 200 kWe generates just a positive return (IRR = 1.7 % after taxes and subsidies) when part of a gas-engine capacity is replaced

  1. NeoAnalysis: a Python-based toolbox for quick electrophysiological data processing and analysis.

    Science.gov (United States)

    Zhang, Bo; Dai, Ji; Zhang, Tao

    2017-11-13

    In a typical electrophysiological experiment, especially one that includes studying animal behavior, the data collected normally contain spikes, local field potentials, behavioral responses and other associated data. In order to obtain informative results, the data must be analyzed simultaneously with the experimental settings. However, most open-source toolboxes currently available for data analysis were developed to handle only a portion of the data and did not take into account the sorting of experimental conditions. Additionally, these toolboxes require that the input data be in a specific format, which can be inconvenient to users. Therefore, the development of a highly integrated toolbox that can process multiple types of data regardless of input data format and perform basic analysis for general electrophysiological experiments is incredibly useful. Here, we report the development of a Python based open-source toolbox, referred to as NeoAnalysis, to be used for quick electrophysiological data processing and analysis. The toolbox can import data from different data acquisition systems regardless of their formats and automatically combine different types of data into a single file with a standardized format. In cases where additional spike sorting is needed, NeoAnalysis provides a module to perform efficient offline sorting with a user-friendly interface. Then, NeoAnalysis can perform regular analog signal processing, spike train, and local field potentials analysis, behavioral response (e.g. saccade) detection and extraction, with several options available for data plotting and statistics. Particularly, it can automatically generate sorted results without requiring users to manually sort data beforehand. In addition, NeoAnalysis can organize all of the relevant data into an informative table on a trial-by-trial basis for data visualization. Finally, NeoAnalysis supports analysis at the population level. With the multitude of general-purpose functions provided

  2. SCIENCE WHERE CULTURE MATTERS: A NEO-CLASSICAL ...

    Indian Academy of Sciences (India)

    Table of contents. SCIENCE WHERE CULTURE MATTERS: A NEO-CLASSICAL APPROACH TO EXPLORE UNTAPPED BACTERIAL DIVERSITY · UNDER GRADUATE RESEARCH An alternative model of doing science · THE EXPANSE OF LIFE · HOW MANY SP. OF BACTERIA IN 1 g SOIL? TORSVIK ET AL 1990.

  3. Program on fuels for transmutation: present status and prospects

    Energy Technology Data Exchange (ETDEWEB)

    Rouault, J.; Garnier, J.C.; Chauvin, N.; Pillon, S. [CEA Cadarache, 13 - Saint-Paul-lez-Durance (France). Dept. d' Etudes des Combustibles

    2001-07-01

    The performance calculations of appropriate fuel cycle facilities and reactor configurations (scenarios) relying on current reactor technologies (Pressurized Water Reactor and Fast neutrons Reactors) or innovative reactors (Accelerator Driven Systems) have proved the scientific feasibility of some P and T strategies. To insure the technological feasibility, a large program on fuels and materials is underway, including advanced concepts for PWRs and the development of specific targets (dispersed fuels) for transmutation in Fast Reactors. Experiments in different reactors including Phenix are being prepared. The program is presented and recent results are given. (author)

  4. Program on fuels for transmutation: present status and prospects

    International Nuclear Information System (INIS)

    Rouault, J.; Garnier, J.C.; Chauvin, N.; Pillon, S.

    2001-01-01

    The performance calculations of appropriate fuel cycle facilities and reactor configurations (scenarios) relying on current reactor technologies (Pressurized Water Reactor and Fast neutrons Reactors) or innovative reactors (Accelerator Driven Systems) have proved the scientific feasibility of some P and T strategies. To insure the technological feasibility, a large program on fuels and materials is underway, including advanced concepts for PWRs and the development of specific targets (dispersed fuels) for transmutation in Fast Reactors. Experiments in different reactors including Phenix are being prepared. The program is presented and recent results are given. (author)

  5. 68Ga/177Lu-NeoBOMB1, a Novel Radiolabeled GRPR Antagonist for Theranostic Use in Oncology.

    Science.gov (United States)

    Dalm, Simone U; Bakker, Ingrid L; de Blois, Erik; Doeswijk, Gabriela N; Konijnenberg, Mark W; Orlandi, Francesca; Barbato, Donato; Tedesco, Mattia; Maina, Theodosia; Nock, Berthold A; de Jong, Marion

    2017-02-01

    Because overexpression of the gastrin-releasing peptide receptor (GRPR) has been reported on various cancer types, for example, prostate cancer and breast cancer, targeting this receptor with radioligands might have a significant impact on staging and treatment of GRPR-expressing tumors. NeoBOMB1 is a novel DOTA-coupled GRPR antagonist with high affinity for GRPR and excellent in vivo stability. The purpose of this preclinical study was to further explore the use of NeoBOMB1 for theranostic application by determining the biodistribution of 68 Ga-NeoBOMB1 and 177 Lu-NeoBOMB1. PC-3 tumor-xenografted BALB/c nu/nu mice were injected with either approximately 13 MBq/250 pmol 68 Ga-NeoBOMB1 or a low (∼1 MBq/200 pmol) versus high (∼1 MBq/10 pmol) peptide amount of 177 Lu-NeoBOMB1, after which biodistribution and imaging studies were performed. At 6 time points (15, 30, 60, 120, 240, and 360 min for 68 Ga-NeoBOMB1 and 1, 4, 24, 48, 96, and 168 h for 177 Lu-NeoBOMB1) postinjection tumor and organ uptake was determined. To assess receptor specificity, additional groups of animals were coinjected with an excess of unlabeled NeoBOMB1. Results of the biodistribution studies were used to determine pharmacokinetics and dosimetry. Furthermore, PET/CT and SPECT/MRI were performed. Injection of approximately 250 pmol 68 Ga-NeoBOMB1 resulted in a tumor and pancreas uptake of 12.4 ± 2.3 and 22.7 ± 3.3 percentage injected dose per gram (%ID/g) of tissue, respectively, at 120 min after injection. 177 Lu-NeoBOMB1 biodistribution studies revealed a higher tumor uptake (17.9 ± 3.3 vs. 11.6 ± 1.3 %ID/g of tissue at 240 min after injection) and a lower pancreatic uptake (19.8 ± 6.9 vs. 105 ± 13 %ID/g of tissue at 240 min after injection) with the higher peptide amount injected, leading to a significant increase in the absorbed dose to the tumor versus the pancreas (200 pmol, 570 vs. 265 mGy/MBq; 10 pmol, 435 vs. 1393 mGy/MBq). Using these data to predict patient dosimetry, we found

  6. Product Liability: A Neo-Austrian Based Perspective

    NARCIS (Netherlands)

    Folmer, H.; Heijman, W.J.M.; Leen, A.R.

    2002-01-01

    The paper is an exercise in a neo-Austrian based economic analysis of product liability. After a short historical introduction, we take two of the basic premises of Austrian economic thought and see which system of product liability results. If costs are subjective and entrepreneurship is the

  7. Neo-institutional Perspectives on Public Management Reform

    NARCIS (Netherlands)

    Gestel, N.M. van; Teelken, J.C.

    2006-01-01

    In this paper, theoretical explanations of competing drivers of change from neo-institutional theory are applied to public sector patterns of reform. The aim is to investigate basic ideas, assumptions, and practices of public management reform over the past two decades and analyze these elements of

  8. NEOShield-2 Project: Final Results on Compositional Characterization of small NEOs

    Science.gov (United States)

    Barucci, Maria Antonieta; Perna, Davide; Fornasier, Sonia; Doressoundiram, Alain; Lantz, Cateline; Popescu, Marcel; Merlin, Frederic; Fulchignoni, Marcello

    2017-10-01

    NEOShield-2 project was selected in the framework of the European Commission H2020 program in answer to the call for “Access technologies and characterisation for Near Earth Objects (NEOs)”. NEOShield-2 project (2015-2017) is a follow-up of the first NEOShield (2012-2015) and includes 11 European Institutions and Industries. The main objectives of NEOShield-2 project are: i) technological development on techniques and instruments needed for GNC for possible asteroid missions and ii) characterization of NEOs of small sizes.Our team at LESIA is the leader of the entire observational program which involved complementary techniques to provide physical and compositional characterization of NEOs. Priority has been given to potential space-mission targets, optimized for mitigation or exploration missions. In this framework an agreement with the European Southern Observatory was signed to obtain Guaranteed Time Observations at the 3.6-meter NTT with an allocation of 30 nights to characterize by spectroscopy the composition of the smaller asteroids. The objects with an absolute magnitude larger than 20 were selected, with a priority for the very small newly discovered objects.We obtained more than 170 new spectra of NEOs. The observations were performed with EFOSC2 instrument. We covered the wavelength interval 0.4-0.92 microns, with a resolution of R=~200. The observed asteroids include 29 asteroids with diameters smaller than 100 meters and 71 with diameters between 100 and 300 m.The taxonomic type has been assigned for 137 individual objects. Our results on NEO mineralogical compositions provide a body of reference data directly applicable to the design and development of mitigation-relevant space missions. Within our survey, we found eight D-types with ΔV funding by European Commission Horizon 2020 program (contract No. PROTEC-2-2014-640351).

  9. Industrial integration of the fuel cycle in Argentina

    International Nuclear Information System (INIS)

    Koll, J.H.; Kittl, J.E.; Parera, C.A.; Coppa, R.C.; Aguirre, E.J.

    1977-01-01

    The paper describes the power reactor construction programme in Argentina for the period 1976-1985, on the basis of which the nuclear fuel requirements have been determined. Activities connected with the fuel cycle commenced in 1950 in Argentina with the prospection and working of uranium deposits. On the basis of the nuclear power programme described, plans have been drawn up for the establishment of the industrial plants that will be needed to ensure the domestic supply of fuel. The demand for fuel is correlated with the availability of uranium resources and it is shown to be desirable from the technical, economic and industrial point of view to integrate the front end of the fuel cycle, keeping the irradiation aspects and the tail end at the development level. The authors report the progress that has been made in this field and describe current programmes covering prospection, concentrate production, nuclear purification, conversion to uranium dioxide, production of special alloys and fuel element fabrication. (author)

  10. Neo-Institutional Approach to the Study of Electronic Government

    Directory of Open Access Journals (Sweden)

    Yan I. Vaslavskiy

    2016-01-01

    Full Text Available The article is devoted to the neo-institutional approach as a methodological basis in the study of electronic government. In this article substantiates the choice of neo-institutional approach to the study of the processes of implementation of information and communication technologies in the activity of state institutions, analyzes the differences of neoinstitutionalism from traditional institutional approach, considers the features of the different directions of neo-institutionalism, namely sociological, historical and rational choice theory. Attention is paid to the reasons for the renewed interest in political institutions in political science. The article emphasizes the importance of considering the electronic government as an institution, and the conditions for its implementation in the Russian political system as the institutional environment. The authors pay special attention to the variety of sociological neo-institutionalism, used, in addition to political science in sociology of organizations. The article substantiates the value of using sociological institutionalism to explore the electronic government based on a comparative analysis of e-government projects in Russia and abroad and explores its heuristic capabilities. It examines the impact of the system of norms and values of the institutional environment on the processes of formation and development of electronic government in Russia. The research capacity of this theory is due to the fact that it allows us to trace the reasons for copying and replication of inefficient practices and organizational and management schemes, to identify the factors impeding innovation use by the state of electronic interaction technologies. It is emphasized that the use of the theory of institutional isomorphism is useful in the sphere of implementation of electronic technologies, in which a key role play pluralism, horizontal managerial communication, inter-agency coordination.

  11. Monitoring for fuel sheath defects in three shipments of irradiated CANDU nuclear fuel

    International Nuclear Information System (INIS)

    Johnson, H.M.

    1978-01-01

    Analyses of radioactive gases within the Pegase shipping flask were performed at the outset and at the completion of three shipments of irradiated nuclear fuel from the Douglas Point Generating Station to Whiteshell Nuclear Research Establishment. No increases in the concentration of active gases, volatiles or particulates were observed. The activity of the WR-1 bay water rose only marginally due to the storage of the fuel. Other tests indicated that minimal surface contamination was present. These data established that defects in fuel element sheaths did not arise during the transport or the handling of this irradiated fuel. The observation has significance for the prospect of irradiated nuclear fuel transfer and handling in preparation for storage or disposal. (author)

  12. Technological development and prospect of alkaline fuel cells

    International Nuclear Information System (INIS)

    Meng Ni; Michael KH Leung; Dennis YC Leung

    2006-01-01

    This paper reviewed the technological development of alkaline fuel cell (AFC). Although the technology was popular in 1970's and 1980's, there has been a decline in AFC research over the past decade, mainly due to the poisoning of CO 2 . Continuous efforts have demonstrated that CO 2 concentration could be reduced to an acceptable level by a number of viable methods such as absorption, adsorption, electrochemical process, electrolyte circulation, use of liquid hydrogen, and use of solid anionic exchange membranes. Literature survey showed that AFC lifetime could achieve up to 5000 hours. In addition, the use of ammonia as a fuel for AFC was identified as a promising technology. Comparison between AFC and proton exchange membrane fuel cell (PEMFC) was presented to evaluate the AFC technology and its economics. The present review and assessment showed the promise of AFC for the coming hydrogen economy and sustainable development. (authors)

  13. Fuel cells 101

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, B.

    2003-06-01

    A capsule history of fuel cells is given, beginning with the first discovery in 1839 by William Grove, a Welsh judge who, when experimenting with electrolysis discovered that by re-combining the two components of electrolysis (water and oxygen) an electric charge was produced. A century later, in 1958, Francis Thomas Bacon, a British scientist demonstrated the first working fuel cell stack, a technology which was licensed and used in the Apollo spacecraft. In Canada, early research on the development of fuel cells was carried out at the University of Toronto, the Defence Research Establishment and the National Research Council. Most of the early work concentrated on alkaline and phosphoric acid fuel cells. In 1983, Ballard Research began the development of the electrolyte membrane fuel cell, which marked the beginning of Canada becoming a world leader in fuel cell technology development. The paper provides a brief account of how fuel cells work, describes the distinguishing characteristics of the various types of fuel cells (alkaline, phosphoric acid, molten-carbonate, solid oxide, and proton exchange membrane types) and their principal benefits. The emphasis is on proton exchange membrane fuel cells because they are the only fuel cell technology that is appropriate for providing primary propulsion power onboard a vehicle. Since vehicles are by far the greatest consumers of fossil fuels, it follows that proton exchange membrane fuel cells will have the greatest potential impact on both environmental matters and on our reliance on oil as our primary fuel. Various on-going and planned fuel cell demonstration projects are also described. 1 fig.

  14. Status and development of uranium prospection methods

    International Nuclear Information System (INIS)

    Barthel, F.

    1978-01-01

    In radiometric prospection, gamma measuring equipment is widely used. Simple instruments, so-called scintillometers, can only measure total radiation while spectrometers permit separate measurements of uranium, thorium, or calcium via daughter products of their decay chains. Depending on the target investigated, airborne, carborne, or footborne methods are employed. In radon prospection the gaseous decay product radon is measured as a sign of hidden uranium enrichment in ground air or water from springs. Due to its high solubility, uranium is well suited for geochemical prospection where uranium concentrations in bodies of water, river sediments, soil and rock types are determined. There is a trend in uranium prospection towards the discovery of hidden orifications. Novel techniques, e.g. airborne geochemistry, isotope chemistry, tracer element measurement, etc. are being tested with a view to their suitability for uranium prospection. (orig./HP) 891 HP/orig.- 892 MKO [de

  15. Domains and facets: hierarchical personality assessment using the revised NEO personality inventory.

    Science.gov (United States)

    Costa, P T; McCrae, R R

    1995-02-01

    Personality traits are organized hierarchically, with narrow, specific traits combining to define broad, global factors. The Revised NEO Personality Inventory (NEO-PI-R; Costa & McCrae, 1992c) assesses personality at both levels, with six specific facet scales in each of five broad domains. This article describes conceptual issues in specifying facets of a domain and reports evidence on the validity of NEO-PI-R facet scales. Facet analysis-the interpretation of a scale in terms of the specific facets with which it correlates-is illustrated using alternative measures of the five-factor model and occupational scales. Finally, the hierarchical interpretation of personality profiles is discussed. Interpretation on the domain level yields a rapid understanding of the individual interpretation of specific facet scales gives a more detailed assessment.

  16. Teams between Neo-Taylorism and Anti-Taylorism

    NARCIS (Netherlands)

    H.D. Pruijt (Hans)

    2003-01-01

    textabstractThe concept of teamworking is the product of two distinct developments. One: a neo- Tayloristic form of organization of work, of which Toyota has shown that it can be very profitable, was packaged and reframed to make it acceptable to the Western public. Two: anti-Tayloristic ways

  17. Objectives and Model Payload Definition for NEO Human Mission Studies

    Science.gov (United States)

    Carnelli, I.; Galvez, A.; Carpenter, J.

    2011-10-01

    ESA has supported studies on NEO threat assessment systems and deflection concepts in the context of the General Studies Programme and in close cooperation with the directorates of Technical and Quality Management and of the Scientific Programme. This work has made it possible to identify a project for Europe to make a significant - yet realistic - contribution to the international efforts in this field: the Don Quijote NEO technology demonstration mission. This paper describes what such a small mission can do to prepare future human exploration and what is the in-situ data that can be obtained through such a project.

  18. Phase-Angle Dependence of Determinations of Diameter, Albedo, and Taxonomy: A Case Study of NEO 3691 Bede

    Science.gov (United States)

    Wooden, Diane H.; Lederer, Susan M.; Jehin, Emmanuel; Howell, Ellen S.; Fernandez, Yan; Harker, David E.; Ryan, Erin; Lovell, Amy; Woodward, Charles E.; Benner, Lance A.

    2015-01-01

    Parameters important for NEO risk assessment and mitigation include Near-Earth Object diameter and taxonomic classification, which translates to surface composition. Diameters of NEOs are derived from the thermal fluxes measured by WISE, NEOWISE, Spitzer Warm Mission and ground-based telescopes including the IRTF and UKIRT. Diameter and its coupled parameters Albedo and IR beaming parameter (a proxy for thermal inertia and/or surface roughness) are dependent upon the phase angle, which is the Sun-target-observer angle. Orbit geometries of NEOs, however, typically provide for observations at phase angles greater than 20 degrees. At higher phase angles, the observed thermal emission is sampling both the day and night sides of the NEO. We compare thermal models for NEOs that exclude (NEATM) and include (NESTM) night-side emission. We present a case study of NEO 3691 Bede, which is a higher albedo object, X (Ec) or Cgh taxonomy, to highlight the range of H magnitudes for this object (depending on the albedo and phase function slope parameter G), and to examine at different phase angles the taxonomy and thermal model fits for this NEO. Observations of 3691 Bede include our observations with IRTF+SpeX and with the 10 micrometer UKIRT+Michelle instrument, as well as WISE and Spitzer Warm mission data. By examining 3691 Bede as a case study, we highlight the interplay between the derivation of basic physical parameters and observing geometry, and we discuss the uncertainties in H magnitude, taxonomy assignment amongst the X-class (P, M, E), and diameter determinations. Systematic dependencies in the derivation of basic characterization parameters of H-magnitude, diameter, albedo and taxonomy with observing geometry are important to understand. These basic characterization parameters affect the statistical assessments of the NEO population, which in turn, affects the assignment of statistically-assessed basic parameters to discovered but yet-to-be-fully-characterized NEOs.

  19. Female Researchers in Neo-Victorian Fiction

    Directory of Open Access Journals (Sweden)

    Lai-Ming Tammy Ho

    2016-06-01

    Full Text Available Neo-Victorian novelists sometimes use postgraduate students – trainee academics – who research nineteenth-century writers as protagonists. This article discusses four neo-Victorian novels, Lloyd Jones’s Mister Pip (2006, Justine Picardie’s Daphne (2008, A.N. Wilson’s A Jealous Ghost (2005 and Scarlett Thomas’s The End of Mr Y (2006, in which female postgraduate students take the centre stage. In Victorian literature, which mirrors the gender bias in the academic world and in society at large at that time, most scholars are male. The contemporary writers’ choice of female trainee academics is worth investigating as it speaks to the visibly changed gender make-up of contemporary academia. However, this utopian situation is complicated by the fact that the writers have chosen to frustrate the characters’ entry into the world of scholarship by having them leave the university environment altogether before the end of the novel. The fact that these females all choose to depart the university forms a contrast with notions of the university found in Victorian novels, in which leaving or not attending university might have detrimental effects on the characters.

  20. From Copenhagen to Neo-Copenhagen Interpretation

    Science.gov (United States)

    de Muynck, Willem M.

    2007-12-01

    Positive and negative features of the Copenhagen interpretation are discussed. As positive features can be mentioned its pragmatism and its awareness of the crucial role of measurement. However, the main part of the contribution is devoted to the negative features, to wit, its pragmatism (once again), its confounding of preparation and measurement, its classical account of measurement, its completeness claims, the ambiguity of its notion of correspondence, its confused notion of complementarity. It is demonstrated how confusions and paradoxes stemming from the negative features of the Copenhagen interpretation can be dealt with in an amended interpretation, to be referred to as `neo-Copenhagen interpretation', in which the role of the measuring instrument is taken seriously by recognizing the quantum mechanical character of its interaction with the microscopic object. The ensuing necessity of extending the notion of a quantum mechanical observable from the Hermitian operator of the standard formalism to the positive operator-valued measure of a generalized formalism yields a sound mathematical basis for a transition from the Copenhagen contextualistic-realist interpretation to the neo-Copenhagen empiricist one. Applications to the uncertainty relations and to the Bell inequalities are briefly discussed.

  1. Educational Modes of Thinking in Neo-Confucianism: A Traditional Lens for Rethinking Modern Education

    Science.gov (United States)

    Hwang, Keumjoong

    2013-01-01

    This article discusses the distinctive educational modes of thinking in Neo-Confucianism, with an interest of extracting Confucian reflective views for modern education of traditionally Confucian East Asia. Neo-Confucian typical modes of thinking on education are characterized as "heart-mind centered" and "learning as…

  2. Neo-phalloplasty with re-innervated latissimus dorsi free flap: a functional study of a novel technique.

    Science.gov (United States)

    Ranno, R; Veselý, J; Hýza, P; Stupka, I; Justan, I; Dvorák, Z; Monni, N; Novák, P; Ranno, S

    2007-01-01

    Twenty two patients with gender dysphoria underwent neo-phalloplasties using a novel technique. Latissimus dorsi musculocutaneus re-innervated free flap was used to allow voluntary rigidity of the neo-penis. From the first 22 patients, 18 have obtained motoric function of reconstructed penis; the "paradox erection" was obtained. 14 patients came for examination after a follow-up period of mean 26.4 months. We evaluated the motility and shape changes of neo-phallus measuring its different size and dimension during relax and muscle contraction. The range of neo-phallus length in relaxed position was between 7 and 17 cm (mean 12.2 cm), its circumference in the same position had a range between 13 and 20 cm (mean 13.7 cm). All patients were able to contract the muscle with an average length reduction of 3.08 cm and an average circumference enlargement of 4 cm. In this study, the dimensions and motility were quantified demonstrating the neo-phallus function and size changes during sexual intercourse.

  3. The uncertain foundation of neo-Darwinism: metaphysical and epistemological pluralism in the evolutionary synthesis.

    Science.gov (United States)

    Delisle, Richard G

    2009-06-01

    The Evolutionary Synthesis is often seen as a unification process in evolutionary biology, one which provided this research area with a solid common theoretical foundation. As such, neo-Darwinism is believed to constitute from this time onward a single, coherent, and unified movement offering research guidelines for investigations. While this may be true if evolutionary biology is solely understood as centred around evolutionary mechanisms, an entirely different picture emerges once other aspects of the founding neo-Darwinists' views are taken into consideration, aspects potentially relevant to the elaboration of an evolutionary worldview: the tree of life, the ontological distinctions of the main cosmic entities (inert matter, biological organisms, mind), the inherent properties of self-organizing matter, evolutionary ethics, and so on. Profound tensions and inconsistencies are immediately revealed in the neo-Darwinian movement once this broader perspective is adopted. This pluralism is such that it is possible to identify at least three distinct and quasi-incommensurable epistemological/metaphysical frameworks as providing a proper foundation for neo-Darwinism. The analysis of the views of Theodosius Dobzhansky, Bernhard Rensch, and Ernst Mayr will illustrate this untenable pluralism, one which requires us to conceive of the neo-Darwinian research agenda as being conducted in more than one research programme or research tradition at the same time.

  4. Cierre percutáneo de fístulas coronario-pulmonares en el adulto

    Directory of Open Access Journals (Sweden)

    Pedro Trujillo, MD

    2014-01-01

    Full Text Available El cierre percutáneo de las fístulas coronario-pulmonares con implante de “coils” es eficaz y pueden realizarlo los cardiólogos intervencionistas de adultos. Se presentan tres casos clínicos de cierre percutáneo exitoso de fístulas coronario-pulmonares con implante de “coils”.

  5. The pseudo-scientific psychologyof the economic neo-liberalism

    Directory of Open Access Journals (Sweden)

    Alečković-Nikolić Mila S.

    2014-01-01

    Full Text Available The aim of the paper is to call attention to logical, axiological, psychological and historical foundations of the problem of economic neo-liberalism. The question is how to achieve psychological comprehension of the historical developpement of the idea of scientific reductionism, the idea of 'common law' and rational utilitarism (Hobbes, Locke, Smith, Bentham, of rationalism (Kant and socialism (Rousseau. In the second part of this analysis the aim is to show that the theory of mechanical simplification in the comprehension of human society is logically wrong theory and that this logically wrong theory is the premise of the social totalitarianism. Finally, the goal of our analysis (specially relevant for the Serbian society trapped today is to show that the world of actual financial reductionism and economic neo-liberalism does not understand at all the real human nature.

  6. Neo4j high performance

    CERN Document Server

    Raj, Sonal

    2015-01-01

    If you are a professional or enthusiast who has a basic understanding of graphs or has basic knowledge of Neo4j operations, this is the book for you. Although it is targeted at an advanced user base, this book can be used by beginners as it touches upon the basics. So, if you are passionate about taming complex data with the help of graphs and building high performance applications, you will be able to get valuable insights from this book.

  7. Experience and prospects of WWER-1000 reactor spent fuel transport

    International Nuclear Information System (INIS)

    Kondratyev, A.N.; Yershov, V.N.; Kozlov, Yu.V.; Kosarev, Yu.A.; Ilyin, Yu.V.; Pavlov, M.S.

    1989-01-01

    The paper deals with the USSR experience in shipping the commercial WWER-1000 reactor spent fuel in TK-10 and TK-13 casks. The cask designs, their basic characteristics and the WWER-1000 spent fuel features are described. An example of calculational/experimental approach in the design of a basket (one of the most important components) for spent fuel assembly (SFA) accommodation in a cask is given. The main problems of future development works are presented in brief. A concept of development of nuclear power industry with the closed fuel cycle is assumed in the Soviet Union, hence the spent nuclear fuel is to be transported from NPPs to reprocessing plants. To transport WWER-1000 spent fuel, the casks of two types were developed. These are: a pilot TK-10 cask of 3t capacity in fuel; a commercial TK-13 cask of ∼6t capacity in fuel. The pilot TK-10 cask is thick-walled (360mm) cylindrical vessel manufactured of steel shells and a bottom welded to each other. The material of the body is carbon steel. There is a steel jacket on the outer side of the cask body and at 120 mm distance off the bottom. On its cylindrical part between the jacket and the body there are T-shaped circular ribs acting as shock-absorbers. The space between the jacket and the body is filled with ethylene glycol solution of 65 degree C crystallization temperature, which functions as a neutron shielding. The TK-10 cask coolant is water or air (nitrogen) at minor excess pressure resulted from FA heatup after the cask sealing

  8. Avaliação do desempenho da tecnologia NeoSoniX TM em cirurgias de catarata Performance evaluation of NeoSoniX TM technology in cataract surgery

    Directory of Open Access Journals (Sweden)

    Leonardo Akaishi

    2006-06-01

    Full Text Available OBJETIVOS: As técnicas e resultados da cirurgia de catarata melhoraram drasticamente com o avanço tecnológico. Um dos motivos para melhoria seria a menor utilização de ultra-som com novos aparelhos de facoemulsificação. O objetivo deste estudo é confirmar na prática a vantagem teórica da caneta NeoSoniX TM. MÉTODOS: Foi realizada uma análise na qual os autores compararam resultados dos parâmetros registrados pelo aparelho de facoemulsificação Legacy durante 300 cirurgias de catarata realizadas com caneta de ultra-som (handpiece convencional e 100 com a caneta NeoSoniX TM. Todas as cirurgias foram realizadas pelo mesmo cirurgião, com a mesma técnica cirúrgica. A escolha da "handpiece" foi aleatória, sendo comparadas, em relação ao grau de dureza das cataratas, os parâmetros de tempo do ultra-som, quantidade de solução salina balanceada e porcentagem de "average power" utilizadas durante as cirurgias. RESULTADOS: Foi realizada análise retrospectiva numa série cronológica de casos, mostrando que em qualquer que seja o grau de dureza da catarata, o tempo de utilização do ultra-som com a caneta NeoSoniX foi inferior ao da caneta convencional (pPURPOSE: The techniques and results of cataract surgery have improved dramatically with technological advancements. One of the reasons for this improvement would be the reduced use of ultrasound with the new phacoemulsification devices. The objective of this study is to confirm the theoretical advantage of the NeoSoniX handpiece. METHODS: The authors compared the results of the parameters recorded by the Legacy phacoemulsification system during 300 cataract surgeries performed with the use of the conventional ultrasound handpiece and 100 performed with the innovative NeosonixTM. All surgeries were performed by the same senior surgeon, using the same surgical technique. The choice of handpiece was random. The handpieces were compared considering cataract grade of hardness, in

  9. Prospects for the application of fuel cells in electric vehicles

    Energy Technology Data Exchange (ETDEWEB)

    Adcock, P L; Newbold, A [Loughborough Univ. of Technology (United Kingdom). Dept. of Transport Technology; Barton, R T; Dudfield, C D; Mitchell, P J; Naylor, P [Loughborough Univ. of Technology (United Kingdom). Dept. of Chemistry

    1992-01-01

    For a hybrid vehicle the use pattern has large effect on the vehicle design. If the vehicle is to be used extensively on the motorway then a continuous high power is required. For the case of a fuel cell battery hybrid vehicle this would require a large fuel cell (> 30 kW) to meet the sustained high power demand. The current high materials and fabrication cost of most fuel cells prohibits the commercial development of such a system. Consequently if fuel cell vehicles are to enter a 'clean car' market, earlier rather than later, alternative configurations must be sought and compromises in terms of performance are inevitable. (orig.).

  10. Status and prospects of WWER in-core fuel management activities

    International Nuclear Information System (INIS)

    Novikov, A.N.; Pavlov, V.I.; Pavlovichev, A.M.; Proselkov, V.N.; Saprykin, V.V.

    1994-01-01

    A short review is given of recent extensive calculational and experimental studies carried out in Russia and Bulgaria for WWER fuel cycle modernization. The main activities performed at Kola NPP, Novovoronezh NPP, Kozloduy NPP and Balakovo NPP are outlined. Based on experience gained, the following improvements in the fuel cycle have been introduced: 1) increased fuel burnup; 2) reduced natural uranium consumption and decreased amount of separation work per energy output unit; 3) increased efficiency of the reactor emergency protection; 4) reduced fast neutron flux onto the reactor vessel. The main characteristics of modernized fuel cycles of WWER-440 and WWER-1000 are presented. 4 tabs., 3 figs., 14 refs

  11. Status and prospects of WWER in-core fuel management activities

    Energy Technology Data Exchange (ETDEWEB)

    Novikov, A N; Pavlov, V I; Pavlovichev, A M; Proselkov, V N; Saprykin, V V [Russian Research Centre Kurchatov Inst., Moscow (Russian Federation)

    1994-12-31

    A short review is given of recent extensive calculational and experimental studies carried out in Russia and Bulgaria for WWER fuel cycle modernization. The main activities performed at Kola NPP, Novovoronezh NPP, Kozloduy NPP and Balakovo NPP are outlined. Based on experience gained, the following improvements in the fuel cycle have been introduced: (1) increased fuel burnup; (2) reduced natural uranium consumption and decreased amount of separation work per energy output unit; (3) increased efficiency of the reactor emergency protection; (4) reduced fast neutron flux onto the reactor vessel. The main characteristics of modernized fuel cycles of WWER-440 and WWER-1000 are presented. 4 tabs., 3 figs., 14 refs.

  12. Prospective studies of HTR fuel cycles involving plutonium

    International Nuclear Information System (INIS)

    Bonin, B.; Greneche, D.; Carre, F.; Damian, F.; Doriath, J.Y.

    2002-01-01

    High Temperature Gas Cooled reactors (HTRs) are able to accommodate a wide variety of mixtures of fissile and fertile materials without any significant modification of the core design. This flexibility is due to an uncoupling between the parameters of cooling geometry, and the parameters which characterize neutronic optimisation (moderation ratio or heavy nuclide concentration and distribution). Among other advantageous features, an HTR core has a better neutron economy than a LWR because there is much less parasitic capture in the moderator (capture cross section of graphite is 100 times less than the one of water) and in internal structures. Moreover, thanks to the high resistance of the coated particles, HTR fuels are able to reach very high burn-ups, far beyond the possibilities offered by other fuels (except the special case of molten salt reactors). These features make HTRs especially interesting for closing the nuclear fuel cycle and stabilizing the plutonium inventory. A large number of fuel cycle studies are already available today, on 3 main categories of fuel cycles involving HTRs : i) High enriched uranium cycle, based on thorium utilization as a fertile material and HEU as a fissile material; ii) Low enriched uranium cycle, where only LEU is used (from 5% to 12%); iii) Plutonium cycle based on the utilization of plutonium only as a fissile material, with (or without) fertile materials. Plutonium consumption at high burnups in HTRs has already been tested with encouraging results under the DRAGON project and at Peach Bottom. To maximize plutonium consumption, recent core studies have also been performed on plutonium HTR cores, with special emphasis on weapon-grade plutonium consumption. In the following, we complete the picture by a core study for a HTR burning reactor-grade plutonium. Limits in burnup due to core neutronics are investigated for this type of fuel. With these limits in mind, we study in some detail the Pu cycle in the special case of a

  13. Using genetic markers to orient the edges in quantitative trait networks: the NEO software.

    Science.gov (United States)

    Aten, Jason E; Fuller, Tova F; Lusis, Aldons J; Horvath, Steve

    2008-04-15

    Systems genetic studies have been used to identify genetic loci that affect transcript abundances and clinical traits such as body weight. The pairwise correlations between gene expression traits and/or clinical traits can be used to define undirected trait networks. Several authors have argued that genetic markers (e.g expression quantitative trait loci, eQTLs) can serve as causal anchors for orienting the edges of a trait network. The availability of hundreds of thousands of genetic markers poses new challenges: how to relate (anchor) traits to multiple genetic markers, how to score the genetic evidence in favor of an edge orientation, and how to weigh the information from multiple markers. We develop and implement Network Edge Orienting (NEO) methods and software that address the challenges of inferring unconfounded and directed gene networks from microarray-derived gene expression data by integrating mRNA levels with genetic marker data and Structural Equation Model (SEM) comparisons. The NEO software implements several manual and automatic methods for incorporating genetic information to anchor traits. The networks are oriented by considering each edge separately, thus reducing error propagation. To summarize the genetic evidence in favor of a given edge orientation, we propose Local SEM-based Edge Orienting (LEO) scores that compare the fit of several competing causal graphs. SEM fitting indices allow the user to assess local and overall model fit. The NEO software allows the user to carry out a robustness analysis with regard to genetic marker selection. We demonstrate the utility of NEO by recovering known causal relationships in the sterol homeostasis pathway using liver gene expression data from an F2 mouse cross. Further, we use NEO to study the relationship between a disease gene and a biologically important gene co-expression module in liver tissue. The NEO software can be used to orient the edges of gene co-expression networks or quantitative trait

  14. Nuclear power and the nuclear fuel cycle

    International Nuclear Information System (INIS)

    Hardy, C.J.; Silver, J.M.

    1985-09-01

    The report provides data and assessments of the status and prospects of nuclear power and the nuclear fuel cycle. The report discusses the economic competitiveness of nuclear electricity generation, the extent of world uranium resources, production and requirements, uranium conversion and enrichment, fuel fabrication, spent fuel treatment and radioactive waste management. A review is given of the status of nuclear fusion research

  15. Metallic fuel development

    International Nuclear Information System (INIS)

    Walters, L.C.

    1987-01-01

    Metallic fuels are capable of achieving high burnup as a result of design modifications instituted in the late 1960's. The gap between the fuel slug and the cladding is fixed such that by the time the fuel swells to the cladding the fission gas bubbles interconnect and release the fission gas to an appropriately sized plenum volume. Interconnected porosity thus provides room for the fuel to deform from further swelling rather than stress the cladding. In addition, the interconnected porosity allows the fuel pin to be tolerant to transient events because as stresses are generated during a transient event the fuel flows rather than applying significant stress to the cladding. Until 1969 a number of metallic fuel alloys were under development in the US. At that time the metallic fuel development program in the US was discontinued in favor of ceramic fuels. However, development had proceeded to the point where it was clear that the zirconium addition to uranium-plutonium fuel would yield a ternary fuel with an adequately high solidus temperature and good compatibility with austenitic stainless steel cladding. Furthermore, several U-Pu-Zr fuel pins had achieved about 6 at.% bu by the late 1960's, without failure, and thus the prospect for high burnup was promising

  16. Functional and Clinical Outcome of Ileal (Studer) Neo-bladder Reconstruction: Single Centre Experience from Pakistan

    International Nuclear Information System (INIS)

    Nazim, S. M.; Ather, M. H.; Abbas, F.

    2014-01-01

    Objective: To determine the medium and long-term outcome of orthotopic continent urinary diversion with ileal (Studer) neo-bladder following radical cystectomy. Study Design: Case series. Place and Duration of Study: Department of Surgery, The Aga Khan University Hospital, Karachi, from January 1998 to September 2010. Methodology: Thirty eight patients underwent radical cystectomy for invasive bladder tumor with ileal neo-bladder (Studer type) reconstruction. Peri-operative and late complications, functional outcome of neo-bladder, urinary continence, metabolic and upper urinary tract status and overall survival were evaluated in all patients. Results: A total of 29 patients (23 males and 6 females) with mean age of 59 +- 12 years were included for the final analysis. The mean duration of surgery (both radical cystectomy and urinary diversion) was 520 +- 70 minutes. Perioperative complication rate was 24% (n=7) with surgical site infection in 4 patients, sepsis in 1 patient and 2 had ureteroileal leak. At 6 months follow-up, 22 patients were fully continent while 7 patients had minimal stress / nocturnal incontinence. The continence rate was 93% (n=27) at one year follow-up. The mean capacity of neo-bladder at 6 months was 384 +- 66 mLs. The late complication rate was 17% (n=5). Three patients developed anastomotic stricture requiring transurethral incision of neo bladder neck, one formed stone in neo-bladder and one developed incision hernia. All patients had preserved renal functions on follow-up. The survival rate was 80% (n=23) at a median follow-up of 66.4 +- 36 months. Two patients developed local recurrence and four developed distant metastasis. Conclusion: Studer ileal neo-bladder is a safe and effective option for urinary diversion in select patients with good oncological and functional outcomes comparable to contemporary literature, even in a low volume center. (author)

  17. Investigating Personality in Stuttering: Results of a Case Control Study Using the NEO-FFI

    Science.gov (United States)

    Bleek, Benjamin; Montag, Christian; Faber, Jennifer; Reuter, Martin

    2011-01-01

    A recent study by Iverach et al. ("Journal of Communication Disorders," 2010) compared persons who stutter with two normative samples in the context of the five-factor model of personality measured by the NEO Five-Factor Inventory (NEO-FFI). Persons who stutter were characterized by higher "Neuroticism," lower…

  18. Ciclo evolutivo do Hepatozoon triatomae (Sporozoa, Haemogregarinidae parasita de triatomíneos Evolution cycle of the Hepatozoon triatomae (Sporozoa, Haemogregarinidae, parasite of triatominea

    Directory of Open Access Journals (Sweden)

    Eduardo Olavo da Rocha e Silva

    1975-09-01

    Full Text Available Relata-se o encontro no Estado de São Paulo, Brasil, de triatomíneos e lagartos, respectivamente o Triatoma arthurneivai e Tropidurus torquatus, parasitados por uma hemogregarina semelhante a Hepatozoon triatomae (Osimani, 1942 Reichenow, 1953. São apresentados aspectos da sua morfologia e estudadas as diversas fases do seu ciclo evolutivo, este inteiramente reproduzido em laboratório.The author relates the discovery of Triatoma arthurneivai and Tropidurus torquatus, in the localities of Lavras de Cima and Santo Antonio, State of São Paulo, Brazil, infected by a hemogregarine similar to Hepatozoon triatomae (Osimani, 1942 Reichenow 1953. He presents certain aspects of its morphology and also studies the several phases of its evolution cycle, which were completed in the laboratory.

  19. Prospects for advanced coal-fuelled fuel cell power plants

    International Nuclear Information System (INIS)

    Jansen, D.; Laag, P.C. van der; Oudhuis, A.B.J.; Ribberink, J.S.

    1994-01-01

    As part of ECN's in-house R and D programmes on clean energy conversion systems with high efficiencies and low emissions, system assessment studies have been carried out on coal gasification power plants integrated with high-temperature fuel cells (IGFC). The studies also included the potential to reduce CO 2 emissions, and to find possible ways for CO 2 extraction and sequestration. The development of this new type of clean coal technology for large-scale power generation is still far off. A significant market share is not envisaged before the year 2015. To assess the future market potential of coal-fuelled fuel cell power plants, the promise of this fuel cell technology was assessed against the performance and the development of current state-of-the-art large-scale power generation systems, namely the pulverized coal-fired power plants and the integrated coal gasification combined cycle (IGCC) power plants. With the anticipated progress in gas turbine and gas clean-up technology, coal-fuelled fuel cell power plants will have to face severe competition from advanced IGCC power plants, despite their higher efficiency. (orig.)

  20. Darwin and Reductionisms: Victorian, Neo-Darwinian and Postgenomic Biologies

    Directory of Open Access Journals (Sweden)

    Angelique Richardson

    2010-10-01

    Full Text Available This article compares the open-ended Darwinism of Charles Darwin, George Lewes, George Eliot and Thomas Hardy with reductive post-Weismann and early eugenist views and more recent neo-Darwinian ideas including literary Darwinism. It argues that some Victorians had a clear sense of the complexities of the natural world, and of the centrality of environment to life. This awareness contrasts with the processes of divorce and isolation that underpin neo-Darwinian understandings of evolutionary development. But biologists and philosophers of biology are now emphasising the complex and dynamic relations between organism and environment in ways that would have appealed to Darwin’s contemporaries. The article establishes that there are significant parallels between mid-Victorian and postgenomic thought.

  1. A role for a neo-sex chromosome in stickleback speciation

    Science.gov (United States)

    Kitano, Jun; Ross, Joseph A.; Mori, Seiichi; Kume, Manabu; Jones, Felicity C.; Chan, Yingguang F.; Absher, Devin M.; Grimwood, Jane; Schmutz, Jeremy; Myers, Richard M.; Kingsley, David M.; Peichel, Catherine L.

    2009-01-01

    Sexual antagonism, or conflict between the sexes, has been proposed as a driving force in both sex chromosome turnover and speciation. Although closely related species often have different sex chromosome systems, it is unknown whether sex chromosome turnover contributes to the evolution of reproductive isolation between species. In this study, we show that a newly evolved sex chromosome harbours genes that contribute to speciation in threespine stickleback fish (Gasterosteus aculeatus). We first identified a neo-sex chromosome system found only in one member of a sympatric species pair in Japan. We then performed genetic linkage mapping of male-specific traits important for reproductive isolation between the Japanese species pair. The neo-X chromosome harbours loci for male courtship display traits that contribute to behavioural isolation, while the ancestral X chromosome contains loci for both behavioural isolation and hybrid male sterility. Our work not only provides strong evidence for a large-X effect on reproductive isolation in a vertebrate system, but also provides direct evidence that a young neo-X chromosome contributes to reproductive isolation between closely related species. Our data suggest that sex chromosome turnover might play a greater role in speciation than previously appreciated. PMID:19783981

  2. Bio fuels. Environment and Energy Aspects and Future Prospects

    International Nuclear Information System (INIS)

    Chiaramonti, D.; Grassi, G.; Tondi, G.; Martelli, F.

    2000-01-01

    The present work aims at describing some of the most important bio fuels (bio diesel, bio methanol, bi oethanol, bio-crude-oil). Environmental effects are also presented, as well as some cost data. Europe and USA are compared, when appropriate. The motivations for a justified and beneficial market penetration of bio fuels in urban areas are reported [it

  3. MuPeXI: prediction of neo-epitopes from tumor sequencing data

    DEFF Research Database (Denmark)

    Bjerregaard, Anne-Mette; Nielsen, Morten; Hadrup, Sine Reker

    2017-01-01

    Personalization of immunotherapies such as cancer vaccines and adoptive T cell therapy depends on identification of patient-specific neo-epitopes that can be specifically targeted. MuPeXI, the mutant peptide extractor and informer, is a program to identify tumor-specific peptides and assess...... their potential to be neo-epitopes. The program input is a file with somatic mutation calls, a list of HLA types, and optionally a gene expression profile. The output is a table with all tumor-specific peptides derived from nucleotide substitutions, insertions, and deletions, along with comprehensive annotation...

  4. Towards a Foundation of Material Approaches in Neo-institutional Theory

    DEFF Research Database (Denmark)

    Cartel, Melodie; Boxenbaum, Eva

    Socio-material approaches of innovation are currently developing fast in neo-institutional theory yet they lack global coherence. As a result, their contribution to the understanding of institutional innovation is fragile. This paper develops a coherent view on socio-material approaches...... of innovation in neo-institutional theory. Drawing on a literature review, we propose that material approaches of institutional innovation focus on the design of institutions. We build on the concept of bricolage to unveil the three activities involved in the design of institutions: crafting, testing...... and evaluating. Eventually, we articulate these findings with existing insights on institutional innovation and develop a multilevel model of institutional innovation....

  5. Chemistry and Bioactivity of NeoMTA Plus™ versus MTA Angelus® Root Repair Materials

    Directory of Open Access Journals (Sweden)

    Sawsan T. Abu Zeid

    2017-01-01

    Full Text Available Objectives. To analyse the chemistry and bioactivity of NeoMTA Plus in comparison with the conventional root repair materials. Method and Materials. Unhydrated and hydrated (initial and final sets materials were analysed by Fourier transform infrared (FTIR spectroscopy and X-ray diffraction (XRD. For bioactivity study, small holes of dentin discs were filled with either materials, immersed in PBS for 15 days, and analysed with FTIR and scanning electron microscope with energy dispersive X-ray (SEM/EDX. The calculation of crystallinity and carbonate/phosphate (CO3/PO4 ratio of surface precipitates (from FTIR and calcium/phosphate (Ca/P ratio (from EDX was statistically analysed using t-test or ANOVA, respectively, at 0.05 significance. Results. Both materials are tricalcium silicate-based that finally react to be calcium silicate hydrate. NeoMTA Plus has relatively high aluminium and sulfur content, with tantalum oxide as an opacifier instead of zirconium oxide in MTA Angelus. NeoMTA Plus showed better apatite formation, higher crystallinity and Ca/P but lower CO3/PO4 ratio than MTA Angelus. SEM showed globular structure with a small particle size in NeoMTA Plus while spherical structure with large particle size in MTA Angelus. Conclusion. Due to fast setting, higher crystallinity, and better bioactivity of NeoMTA Plus, it can be used as a pulp and root repair material.

  6. Nuclear fuel cycle techniques

    International Nuclear Information System (INIS)

    Pecqueur, Michel; Taranger, Pierre

    1975-01-01

    The production of fuels for nuclear power plants involves five principal stages: prospecting of uranium deposits (on the ground, aerial, geochemical, geophysical, etc...); extraction and production of natural uranium from the deposits (U content of ores is not generally high and a chemical processing is necessary to obtain U concentrates); production of 235 U enriched uranium for plants utilizing this type of fuel (a description is given of the gaseous diffusion process widely used throughout the world and particularly in France); manufacture of suitable fuel elements for the different plants; reprocessing of spent fuels for the purpose of not only recovering the fissile materials but also disposing safely of the fission products and other wastes [fr

  7. Fuel elements and safety engineering goals

    International Nuclear Information System (INIS)

    Schulten, R.; Bonnenberg, H.

    1990-01-01

    There are good prospects for silicon carbide anti-corrosion coatings on fuel elements to be realised, which opens up the chance to reduce the safety engineering requirements to the suitable design and safe performance of the ceramic fuel element. Another possibility offered is combined-cycle operation with high efficiencies, and thus good economic prospects, as with this design concept combining gas and steam turbines, air ingress due to turbine malfunction is an incident that can be managed by the system. This development will allow economically efficient operation also of nuclear power reactors with relatively small output, and hence contribute to reducing CO 2 emissions. (orig./DG) [de

  8. Nuclear fuels policy. Report of the Atlantic Council's Nuclear Fuels Policy Working Group

    International Nuclear Information System (INIS)

    Anon.

    1976-01-01

    This Policy Paper recommends the actions deemed necessary to assure that future U.S. and non-Communist countries' nuclear fuels supply will be adequate, considering the following: estimates of modest growth in overall energy demand, electrical energy demand, and nuclear electrical energy demand in the U.S. and abroad, predicated upon the continuing trends involving conservation of energy, increased use of electricity, and moderate economic growth (Chap. I); possibilities for the development and use of all domestic resources providing energy alternatives to imported oil and gas, consonant with current environmental, health, and safety concerns (Chap. II); assessment of the traditional energy sources which provide current alternatives to nuclear energy (Chap. II); evaluation of realistic expectations for additional future energy supplies from prospective technologies: enhanced recovery from traditional sources and development and use of oil shales and synthetic fuels from coal, fusion and solar energy (Chap. II); an accounting of established nuclear technology in use today, in particular the light water reactor, used for generating electricity (Chap. III); an estimate of future nuclear technology, in particular the prospective fast breeder (Chap. IV); current and projected nuclear fuel demand and supply in the U.S. and abroad (Chaps. V and VI); the constraints encountered today in meeting nuclear fuels demand (Chap. VII); and the major unresolved issues and options in nuclear fuels supply and use (Chap. VIII). The principal conclusions and recommendations (Chap. IX) are that the U.S. and other industrialized countries should strive for increased flexibility of primary energy fuel sources, and that a balanced energy strategy therefore depends on the secure supply of energy resources and the ability to substitute one form of fuel for another

  9. Neo-sex chromosomes in the black muntjac recapitulate incipient evolution of mammalian sex chromosomes

    DEFF Research Database (Denmark)

    Zhou, Qi; Wang, Jun; Huang, Ling

    2008-01-01

    in coding regions of eight investigated genes as well as cis-regulatory regions of two housekeeping genes. In vivo assays characterized a neo-Y insertion in the promoter of the CLTC gene that causes a significant reduction in allelic expression. A neo-Y-linked deletion in the 3'-untranslated region of gene...

  10. [Neo-'hippocratism' in Bernardino Ramazzini].

    Science.gov (United States)

    Marinozzi, Silvia; Conforti, Maria; Gazzaniga, Valentina

    2011-01-01

    Neo-hippocratism is a rational and mechanic method to explain pathological phenomena and discover the causes of diseases. Bernardino Ramazzini uses Hippocratic empirical observation to investigate the relations between the alterations of the air - due to mephitic vapours, of organic and inorganic origin - and the development of pathological processes. His notion of corruption of the atmosphere as the origin of epidemics and specific diseases, and that of prevention as the main strategy of modern medicine, is developed in medical literature and in the public medicine projects of the end of the Seventeenth century.

  11. Catalytic Conversion of Bio-oil to Fuel for Transportation

    DEFF Research Database (Denmark)

    Mortensen, Peter Mølgaard

    identied as a prospective route to bio-fuels. The upgrading is most favorably done by hydrodeoxygenation (HDO), producing bio-fuels at a quality equivalent to conventional fossil fuels. The topic of this Ph.D. thesis has been the development of active and stable catalysts for this reaction. In the search...

  12. Leadership Pipeline – en neo-weberiansk revitalisering af bureaukratiet?

    DEFF Research Database (Denmark)

    Dahl, Kristian Aagaard; Nielsen, Jeppe

    2015-01-01

    Selvom Leadership Pipeline har vundet indpas i mange private og offentlige organisationer, er den akademiske litteratur om ledelsesmodellen indtil videre forbavsende beskeden. I denne artikel søger vi at indkredse svar på, hvorvidt Leadership Pipeline udgør et (gammeldags) bureaukratisk perspektiv...... på ledelse. Vores dokumentanalyse viser, at Leadership Pipeline modellen bygger på weberianske og neo-weberianske principper om klare over-/underordnelsesforhold og faste referencestrukturer. Samtidig viser en nøjere granskning, at modellen også inkluderer andre ledelsesdyder med betoning af...... meningsskabelse, innovation, helhedsorientering og ledelse på tværs. Det leder os til at foreslå, at Leadership Pipeline modellen i dens udtryksform udviser ambidekstrale træk, hvor weberianske og neo- weberianske principper søges koblet med tilsyneladende modsatrettede, postmoderne ledelsesforståelser. Vi...

  13. Conspirators in a Neo-Liberal Agenda? Adult Educators in Second-Chance Private Training Establishments

    Science.gov (United States)

    Walker, Judith

    2008-01-01

    This paper presents the findings of a qualitative study that explored the impact of neo-liberal policy and ideology on educators and directors working in second-chance Private Training Establishments (PTEs) which were created at the height of the neo-liberal reforms in New Zealand. By examining the experiences of 14 educators and directors in four…

  14. Target selection and mass estimation for manned NEO exploration using a baseline mission design

    Science.gov (United States)

    Boden, Ralf C.; Hein, Andreas M.; Kawaguchi, Junichiro

    2015-06-01

    In recent years Near-Earth Objects (NEOs) have received an increased amount of interest as a target for human exploration. NEOs offer scientifically interesting targets, and at the same time function as a stepping stone for achieving future Mars missions. The aim of this research is to identify promising targets from the large number of known NEOs that qualify for a manned sample-return mission with a maximum duration of one year. By developing a baseline mission design and a mass estimation model, mission opportunities are evaluated based on on-orbit mass requirements, safety considerations, and the properties of the potential targets. A selection of promising NEOs is presented and the effects of mission requirements and restrictions are discussed. Regarding safety aspects, the use of free-return trajectories provides the lowest on-orbit mass, when compared to an alternative design that uses system redundancies to ensure return of the spacecraft to Earth. It is discovered that, although a number of targets are accessible within the analysed time frame, no NEO offers both easy access and high incentive for its exploration. Under the discussed aspects a first human exploration mission going beyond the vicinity of Earth will require a trade off between targets that provide easy access and those that are of scientific interest. This lack of optimal mission opportunities can be seen in the small number of only 4 NEOs that meet all requirements for a sample-return mission and remain below an on-orbit mass of 500 metric Tons (mT). All of them require a mass between 315 and 492 mT. Even less ideal, smaller asteroids that are better accessible require an on-orbit mass that exceeds the launch capability of future heavy lift vehicles (HLV) such as SLS by at least 30 mT. These mass requirements show that additional efforts are necessary to increase the number of available targets and reduce on-orbit mass requirements through advanced mission architectures. The need for on

  15. Sistematização de Normas Regulatórias: uma abordagem baseada no neo-institucionalismo / Systematizing Regulations: An Approach Focused on Neo-Institutionalism

    Directory of Open Access Journals (Sweden)

    João Alberto de Oliveira Lima

    2016-05-01

    Full Text Available Purpose – This paper proposes an approach based on neo-institutionalism to assist regulations systematization activity. Methodology/approach/design – Interdisciplinary bibliographic research in Philosophy of Language, Information Science and Law. Findings – The neo-institutionalism, mainly in the form proposed by Dick Ruiter, offers a conceptual framework that can assist in systematizing regulations. Practical implications – This article proposes an approach to the systematization of regulations that, despite its importance to the simplification of the legal system and to the legal certainty, has not been executed as required by law. Originality/value – The originality of the proposed approach lies in the combination of concepts and theories from Philosophy of Language, Information Science and Law, as a way to deal with the problem of regulations systematization.

  16. Application of GAMESS/NEO to quantum calculations of muonic molecules

    Energy Technology Data Exchange (ETDEWEB)

    Sheely, Eugene V; Burggraf, Larry W [Air Force Institute of Technology, AFIT/ENP, 2950 Hobson Way, Wright-Patterson Air Force Base, OH 45433 (United States); Adamson, Paul E [High Power Microwave (HPM) Technologies Branch, HPM Division, Directed Energy Directorate, Air Force Research Laboratory, Kirtland AFB, NM 87117 (United States); Duan, Xiaofeng F [DoD Supercomputing Resource Center (DSRC), Air Force Research Laboratory, 2435 Fifth Street, Bldg 676, Wright-Patterson Air Force Base, OH 45433 (United States); Schmidt, Mike W, E-mail: Eugene.Sheely@afit.ed [Department of Chemistry, Iowa State University, 201 Spedding Hall, Ames, IA 50011 (United States)

    2010-04-01

    The General Atomic and Molecular Electronic Structure System (GAMESS) has been modified to perform studies involving negative muons. This system, coupled with the Nuclear-Electronic Orbital (NEO) method enables the ab-initio study of muonic atoms where both the negative muon and the positive nuclei are modeled as quantum particles. This is of particular usefulness in the study light nuclei, muonic atoms, such as is encountered in muon-catalyzed fusion. NEO was also modified to allow the inclusion of positive exotic-particles to be studied using open and closed shell Hartree-Fock and Configuration Interaction. Capitalizing on these modified methods, the muon density and vibrational dynamics of some light muonic molecules have been analyzed.

  17. TIEMPO RECOMENDADO PARA UNA NUEVA CONCEPCIÓN POST ABORTO ESPONTÁNEO

    OpenAIRE

    Baltra E,Estebeni; de Mayo G,Tomás; Rojas G,María de los Ángeles; Arraztoa V,José Antonio

    2008-01-01

    Antecedentes: La recomendación del clínico acerca del tiempo a esperar para una nueva concepción post aborto espontáneo correspondería a una práctica basada en la experiencia y no en la evidencia. Objetivo: Análisis crítico de la literatura científica, en relación al tiempo de espera para intentar un nuevo embarazo en pacientes con aborto espontáneo, y los resultados materno-perinatales asociados a las diferentes conductas. Búsqueda sistemática en múltiples bases de datos. Resultados: Se enco...

  18. An urban neo-poverty population-based quality of life and related social characteristics investigation from northeast China.

    Science.gov (United States)

    Ou, Fengrong; Li, Kai; Gao, Qian; Liu, Dan; Li, Jinghai; Hu, Liwen; Wu, Xian; Edmiston, E Kale; Liu, Yang

    2012-01-01

    To investigate quality of life (QOL) and related characteristics among an urban neo-poverty population in northeast China, and to compare this population with a traditional poverty cohort. The research was a cross-sectional survey executed from June 2005 to October 2007, with a sample of 2940 individuals ages 36 to 55 in three different industrial cities of northeast China. Data were collected on QOL status and sociodemographic characteristics. QOL was assessed using the 36-item Short Form Health Survey (Chinese version). Multiple regression analysis was employed to analyze association between sociodemographic variables and QOL. The scores for QOL in the neo-poverty group were higher than those in the traditional poverty group, but lower than those in the general population. When the neo-poverty population was divided into two subgroups by age, 36-45 years and 46-55 years, the differences in QOL scores were not significant. However, there were significant differences in several dimensions between two subgroups according to unemployment time (5 years). Additionally, stepwise regression analysis indicated that disease burden, including disease and medical expenditures, was a common risk factor for declining QOL in the neo-poverty group. Despite some limitations, this study provides initial evidence that the QOL of the urban neo-poverty population lies between that of the general population and traditional poverty. QOL of the neo-poverty group approached QOL of the traditional poverty group with increased unemployment years. In addition to decreased income, disease burden is the most important factor influencing QOL status in urban neo-poverty.

  19. Effect of Slip Time in Forming Neo-Esophageal Stenosis After Replacement of a Thoracic Esophagus With Nitinol Artificial Esophagus.

    Science.gov (United States)

    Liang, Xian-Liang; Liang, Jian-Hui

    2015-07-01

    Attempts have been made to investigate the effect of slip time of nitinol artificial esophagus for forming neo-esophageal stenosis after replacement of a thoracic esophagus with nitinol artificial esophagus in 20 experimental pigs. The pigs whose slip time was less than 90 days postoperatively had severe dysphagia (Bown's III) immediately after they were fed, and the dysphagia aggravated gradually later on (Bown's III-IV). The pigs whose slip time was more than 90 days postoperatively had mild/moderate dysphagia (Bown's I-II) immediately after they were fed, and the dysphagia relieved gradually later on (Bown's II-I-0). The ratios between the diameter of neo-esophagus in different slip time and normal esophagus were 25% (at 2 months postoperatively), 58% (at 4 months postoperatively), and 93% (at 6 months postoperatively), respectively. The relationship between nitinol artificial esophagus slip time and neo-esophageal stenosis showed a positive correlation. After replacement of a thoracic esophagus with nitinol artificial esophagus, the artificial esophageal slip time not only affected the original diameter of the neo-esophagus immediately, but also affected the neo-esophageal scar stricture forming process later on. The narrowing of neo-esophagus is caused by overgrowth of scar tissue. But there is the positive correlation between artificial esophagus slip time and neo-esophageal stenosis, so this can be a way of overcoming neo-esophageal stenosis by delaying slip time of artificial esophagus. Copyright © 2015 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

  20. Overview of the uranium prospecting in Uruguay

    International Nuclear Information System (INIS)

    Rossi, P; Vaz Chaves, N.; Pirelli, H.

    1985-01-01

    The report is about Uranium prospection in Uruguay by DINAMIGE experts. They were explained the radioactive properties elements in Uranium and its importance as a fuel oil for electric energy generation

  1. Reaction of North American neo-Thomism against the «Intelligent Design»

    Directory of Open Access Journals (Sweden)

    Desiderio Parrilla Martínez

    2017-08-01

    Full Text Available The doctrine of «Intelligent Design» formulated by Phillip E. Johnson, Michael Behe, William A. Dembski and Stephen C. Meyer is presented as a scientific alternative to neo-Darwinism. For philosophical naturalism or atheism is only a pseudo-science dependent of «Protestant creationism» and the literal biblical interpretation. The best philosophical critiques, however, come from American neo-Thomism. This paper presents the main arguments used by the Thomism in his polemic against the doctrine of «Intelligent Design».

  2. Recent achievements of the neo-deterministic seismic hazard assessment in the CEI region

    International Nuclear Information System (INIS)

    Panza, G.F.; Vaccari, F.; Kouteva, M.

    2008-03-01

    A review of the recent achievements of the innovative neo-deterministic approach for seismic hazard assessment through realistic earthquake scenarios has been performed. The procedure provides strong ground motion parameters for the purpose of earthquake engineering, based on the deterministic seismic wave propagation modelling at different scales - regional, national and metropolitan. The main advantage of this neo-deterministic procedure is the simultaneous treatment of the contribution of the earthquake source and seismic wave propagation media to the strong motion at the target site/region, as required by basic physical principles. The neo-deterministic seismic microzonation procedure has been successfully applied to numerous metropolitan areas all over the world in the framework of several international projects. In this study some examples focused on CEI region concerning both regional seismic hazard assessment and seismic microzonation of the selected metropolitan areas are shown. (author)

  3. Composite Beings in Neo-Babylonian Art

    OpenAIRE

    Gane, Constance E.

    2012-01-01

    An examination of all the extant, provenanced depictions of composite beings, Mischwesen, in Neo-Babylonian iconography sheds important new light on the worldview of the last great Mesopotamian civilization. The types of hybrids that are portrayed include such disparate forms as the apkallu and the genius in human form, as well as creatures based on bulls, lions, canines, winged quadrupeds, fish, birds, scorpions, and snakes. Each composite being is analyzed in terms of its physical component...

  4. Lessons from hot spot analysis for fragment-based drug discovery

    Science.gov (United States)

    Hall, David R.; Vajda, Sandor

    2015-01-01

    Analysis of binding energy hot spots at protein surfaces can provide crucial insights into the prospects for successful application of fragment-based drug discovery (FBDD), and whether a fragment hit can be advanced into a high affinity, druglike ligand. The key factor is the strength of the top ranking hot spot, and how well a given fragment complements it. We show that published data are sufficient to provide a sophisticated and quantitative understanding of how hot spots derive from protein three-dimensional structure, and how their strength, number and spatial arrangement govern the potential for a surface site to bind to fragment-sized and larger ligands. This improved understanding provides important guidance for the effective application of FBDD in drug discovery. PMID:26538314

  5. Thorium fuel cycle - Potential benefits and challenges

    International Nuclear Information System (INIS)

    2005-05-01

    There has been significant interest among Member States in developing advanced and innovative technologies for safe, proliferation resistant and economically efficient nuclear fuel cycles, while minimizing waste and environmental impacts. This publication provides an insight into the reasons for renewed interest in the thorium fuel cycle, different implementation scenarios and options for the thorium cycle and an update of the information base on thorium fuels and fuel cycles. The present TECDOC focuses on the upcoming thorium based reactors, current information base, front and back end issues, including manufacturing and reprocessing of thorium fuels and waste management, proliferation-resistance and economic issues. The concluding chapter summarizes future prospects and recommendations pertaining to thorium fuels and fuel cycles

  6. Nonuniversal gaugino masses and seminatural supersymmetry in view of the Higgs boson discovery

    Energy Technology Data Exchange (ETDEWEB)

    Martin, Stephen P. [Santa Barbara, KITP

    2014-02-20

    I consider models with non-universal gaugino masses at the gauge coupling unification scale, taking into account the Higgs boson discovery. Viable regions of parameter space are mapped and studied in the case of non-universality following from an F-term in a linear combination of singlet and adjoint representations of SU(5). I consider, in particular, "semi-natural" models that have small \\mu, with gaugino masses dominating the supersymmetry breaking terms at high energies. Higgsino-like particles are then much lighter than all other superpartners, and the prospects for discovery at the Large Hadron Collider can be extremely challenging.

  7. Desafíos proyectuales contemporáneos.

    Directory of Open Access Journals (Sweden)

    Dra. Arq. Laura Fernández Quinteiro

    2014-12-01

    Full Text Available «Desafíos Proyectuales Contemporáneos» es un artículo de reflexión que trata sobre el problema que enfrentan gran cantidad de arquitectos actualmente al tener que intervenir sobre obras preexistentes realizadas por destacados arquitectos modernos y de valor patrimonial. Nos referimos a obras originales muy valoradas por la cultura arquitectónica y la historiografía de la arquitectura nacional. Para el presente trabajo se seleccionaron tres obras relevantes realizadas por el arquitecto uruguayo Julio Vilamajó entre 1931 y 1947, correspondientes a diferentes localizaciones, escalas y programas arquitectónicos, caídas con el transcurso de los años en desuso total o parcial. Se reflexiona sobre la forma en que se llevaron a cabo proyectos contemporáneos de adaptación a nuevos requerimientos y necesidades. La esencia del problema radica en descubrir y comprender la naturaleza compositiva y el espíritu de la preexistencia, conocer sus cualidades y valores originales, cuáles de ellos permanecen inalterados, cuáles son transformados y qué nuevos valores incorpora la actuación

  8. The prospects for hard coal as a fuel for the Polish power sector

    International Nuclear Information System (INIS)

    Kaminski, Jacek; KudeLko, Mariusz

    2010-01-01

    This paper presents the prospects for the development of the Polish hard coal sector from the perspective of the power sector. The most important issues determining the mid- and long-term future for domestic coal production are: (1) the development of the economy, hence the demand for electricity, (2) regulations (mostly environmental) affecting the power sector, (3) the competitiveness of coal-based technologies, and (4) the costs of domestic coal production. Since the range of issues and relations being considered is very broad, a specific method needs to be employed for the quantitative analysis. The tool applied in this study is the partial equilibrium model POWER-POL, in which both the coal and the power sectors are incorporated. The model focuses on energy-economy-environmental issues without capturing detailed macroeconomic links. The model was run under six scenario assumptions. The results show that the domestic coal sector should maintain its position as a key supplier of primary energy for the Polish power sector. However, the environmental regulations to which the domestic power sector has to conform will decrease the share of coal in the fuel-mix. Since the investment processes in this sector are usually long-term, the effects of changes will be noticeable from 2015 onwards. - Research highlights: →Application of the partial equilibrium model POWER-POL for a quantitative analysis. →Coal will maintain its dominant position in the Polish heat and electricity production fuel-mix at least up to 2020. →Attractiveness of domestic hard coal supplies will depend on the environmental regulations (mostly on the EU level) and development in the world coal market. →The first nuclear power plant will be put into operation in 2020.

  9. Ganoderma neo-japonicum Imazeki revisited: Domestication study and antioxidant properties of its basidiocarps and mycelia

    Science.gov (United States)

    Tan, Wee-Cheat; Kuppusamy, Umah Rani; Phan, Chia-Wei; Tan, Yee-Shin; Raman, Jegadeesh; Anuar, Azliza Mad; Sabaratnam, Vikineswary

    2015-01-01

    Mushroom cultivation benefits humankind as it deliberately encourages wild mushrooms to be commercially propagated while recycling agricultural wastes. Ganoderma neo-japonicum is a rare polypore mushroom found growing on decaying Schizostachyum brachycladium (a tropical bamboo) clumps in Malaysia. The Malaysian indigenous tribes including the Temuans and Temiars use the basidiocarps of G. neo-japonicum to treat various ailments including diabetes. In this study, the domestication of G. neo-japonicum in artificial logs of different agricultural residues was investigated. Sawdust promoted the mycelia spawn colonisation in the shortest period of 38 ± 0.5 days. However, only sawdust and bamboo dust supported the primodia formation. Complex medium supported mycelium growth in submerged cultures and 27.11 ± 0.43 g/L of mycelia was obtained after 2 weeks of cultivation at 28 °C and 200 rpm. Antioxidant potential in mushroom may be influenced by different cultivation and extraction methods. The different extracts from the wild and cultivated basidiocarps as well as mycelia were then tested for their antioxidant properties. Aqueous and ethanol extracts of mycelia and basidiocarps tested had varying levels of antioxidant activities. To conclude, domestication of wild G. neo-japonicum using agroresidues may ensure a continuous supply of G. neo-japonicum for its medicinal use while ensuring the conservation of this rare species. PMID:26213331

  10. Liberal Values at a Time of Neo-Liberalism

    Science.gov (United States)

    Evans, Mary

    2014-01-01

    Critical responses to changes in UK higher education have emerged from various quarters. This article suggests that some of these responses are collusive with neo-liberalism and that a greater attention might be paid to the possibilities of the word "liberal" and to the more democratic implications of certain US initiatives.

  11. Near-Earth Object Survey Simulation Software

    Science.gov (United States)

    Naidu, Shantanu P.; Chesley, Steven R.; Farnocchia, Davide

    2017-10-01

    There is a significant interest in Near-Earth objects (NEOs) because they pose an impact threat to Earth, offer valuable scientific information, and are potential targets for robotic and human exploration. The number of NEO discoveries has been rising rapidly over the last two decades with over 1800 being discovered last year, making the total number of known NEOs >16000. Pan-STARRS and the Catalina Sky Survey are currently the most prolific NEO surveys, having discovered >1600 NEOs between them in 2016. As next generation surveys such as Large Synoptic Survey Telescope (LSST) and the proposed Near-Earth Object Camera (NEOCam) become operational in the next decade, the discovery rate is expected to increase tremendously. Coordination between various survey telescopes will be necessary in order to optimize NEO discoveries and create a unified global NEO discovery network. We are collaborating on a community-based, open-source software project to simulate asteroid surveys to facilitate such coordination and develop strategies for improving discovery efficiency. Our effort so far has focused on development of a fast and efficient tool capable of accepting user-defined asteroid population models and telescope parameters such as a list of pointing angles and camera field-of-view, and generating an output list of detectable asteroids. The software takes advantage of the widely used and tested SPICE library and architecture developed by NASA’s Navigation and Ancillary Information Facility (Acton, 1996) for saving and retrieving asteroid trajectories and camera pointing. Orbit propagation is done using OpenOrb (Granvik et al. 2009) but future versions will allow the user to plug in a propagator of their choice. The software allows the simulation of both ground-based and space-based surveys. Performance is being tested using the Grav et al. (2011) asteroid population model and the LSST simulated survey “enigma_1189”.

  12. Nuclear spent fuel management. Experience and options

    International Nuclear Information System (INIS)

    1986-01-01

    Spent nuclear fuel can be stored safely for long periods at relatively low cost, but some form of permanent disposal will eventually be necessary. This report examines the options for spent fuel management, explores the future prospects for each stage of the back-end of the fuel cycle and provides a thorough review of past experience and the technical status of the alternatives. Current policies and practices in twelve OECD countries are surveyed

  13. Neo-Liberalism and Universal State Education: The Cases of Denmark, Norway and Sweden 1980-2011

    Science.gov (United States)

    Wiborg, Susanne

    2013-01-01

    This article investigates neo-liberal policy on education in Denmark, Norway and Sweden. Traditionally, the edifice of the education system in these Scandinavian countries has been built on egalitarian values, but over the last 20 years they have increasingly adopted market-led reforms of education. The extent of neo-liberal policy varies between…

  14. Visiting the neo-liberal university

    DEFF Research Database (Denmark)

    Sørensen, Asger

    2015-01-01

    dramatic controversy ever encountered at a Danish university, the Koldau case, which reached national newspaper headlines and broadcasting in two rounds in 2011 and 2012. In the fourth section, I will interpret the case as an educational controversy in light of two conflicting ideas of the modern...... university, which may be attributed to two leading Enlightenment figures, Wilhelm von Humboldt and Denis Diderot. The conclusion is that to some extent, the failure to resist the neo-liberal university reforms in Denmark and the UK, and the drama of the Koldau case, may be explained with reference...

  15. Impact of neo-adjuvant Sorafenib treatment on liver transplantation in HCC patients - a prospective, randomized, double-blind, phase III trial

    International Nuclear Information System (INIS)

    Hoffmann, Katrin; Ganten, Tom; Gotthardtp, Daniel; Radeleff, Boris; Settmacher, Utz; Kollmar, Otto; Nadalin, Silvio; Karapanagiotou-Schenkel, Irini; Kalle, Christof von; Jäger, Dirk; Büchler, Markus W; Schemmer, Peter

    2015-01-01

    Liver Transplantation (LT) is treatment of choice for patients with hepatocellular carcinoma (HCC) within MILAN Criteria. Tumour progression and subsequent dropout from waiting list have significant impact on the survival. Transarterial chemoembolization (TACE) controls tumour growth in the treated HCC nodule, however, the risk of tumour development in the untreated liver is increased by simultaneous release of neo-angiogenic factors. Due to its anti-angiogenic effects, Sorafenib delays the progression of HCC. Aim of this study was to determine whether combination of TACE and Sorafenib improves tumour control in HCC patients on waiting list for LT. Fifty patients were randomly assigned on a 1:1 ratio in double-blinded fashion at four centers in Germany and treated with TACE plus either Sorafenib (n = 24) or placebo (n = 26). The end of treatment was development of progressive disease according to mRECIST criteria or LT. The primary endpoint of the trial was the Time-to-Progression (TTP). Other efficacy endpoints were Tumour Response, Progression-free Survival (PFS), and Time-to-LT (TTLT). The median time of treatment was 125 days with Sorafenib and 171 days with the placebo. Fourteen patients (seven from each group) developed tumour progression during the course of the study period. The Hazard Ratio of TTP was 1.106 (95% CI: 0.387, 3.162). The results of the Objective Response Rate, Disease Control Rate, PFS, and TTLT were comparable in both groups. The incidence of AEs was comparable in the placebo group (n = 23, 92%) and in the Sorafenib group (n = 23, 96%). Twelve patients (50%) on Sorafenib and four patients (16%) on placebo experienced severe treatment-related AEs. The TTP is similar after neo-adjuvant treatment with TACE and Sorafenib before LT compared to TACE and placebo. The Tumour Response, PFS, and TTLT were comparable. The safety profile of the Sorafenib group was similar to that of the placebo group

  16. Prospects for neutron-antineutron transition search

    International Nuclear Information System (INIS)

    Kamyshkov, Y.; Tennessee Univ., Knoxville, TN

    1996-01-01

    Presently-available sources of free neutrons can allow an improvement in the discovery potential of a neutron-antineutron transition search by four orders of magnitude as compared to that of the most recent reactor-based search experiment performed at ILL in Grenoble. This would be equivalent to a characteristic neutron-antineutron transition time limit of >10 10 seconds. With future dedicated neutron-source Facilities, with further progress in cold-neutron- moderator techniques, and with a vertical experiment layout, the discovery potential could ultimately be pushed by another factor of ∼100 corresponding to a characteristic transition time limit of ∼10 11 seconds. Prospects for, and relative merits of, a neutron-antineutron oscillation search in intranuclear transitions are also discussed

  17. Status of nuclear fuel reprocessing, spent fuel storage, and high-level waste disposal. Nuclear Fuel Cycle Committee, California Energy Resources Conservation and Development Commission. Draft report

    International Nuclear Information System (INIS)

    Anon.

    1978-01-01

    An analysis of the current status of technologies and issues in the major portions of the back-end of the nuclear fuel cycle is presented. The discussion on nuclear fuel reprocessing covers the reprocessing requirement, reprocessing technology assessment, technology for operation of reprocessing plants, and approval of reprocessing plants. The chapter devoted to spent fuel storage covers the spent fuel storge problem, the legislative response, options for maintaining full core discharge capacity, prospective availability of alterntive storage options, and the outlook for California. The existence of a demonstrated, developed high-level waste disposal technology is reviewed. Recommendations for Federal programs on high-level waste disposal are made

  18. Economic prospects of the Integral Fast Reactor (IFR) fuel cycle

    International Nuclear Information System (INIS)

    Chang, Y.I.; Till, C.E.

    1991-01-01

    The IFR fuel cycle based on pyroprocessing involves only few operational steps and the batch-oriented process equipment systems are compact. This results in major cost reductions in all of three areas of reprocessing, fabrication, and waste treatment. This document discusses the economic aspects of this fuel cycle

  19. Deciphering neo-sex and B chromosome evolution by the draft genome of Drosophila albomicans

    Directory of Open Access Journals (Sweden)

    Zhou Qi

    2012-03-01

    Full Text Available Abstract Background Drosophila albomicans is a unique model organism for studying both sex chromosome and B chromosome evolution. A pair of its autosomes comprising roughly 40% of the whole genome has fused to the ancient X and Y chromosomes only about 0.12 million years ago, thereby creating the youngest and most gene-rich neo-sex system reported to date. This species also possesses recently derived B chromosomes that show non-Mendelian inheritance and significantly influence fertility. Methods We sequenced male flies with B chromosomes at 124.5-fold genome coverage using next-generation sequencing. To characterize neo-Y specific changes and B chromosome sequences, we also sequenced inbred female flies derived from the same strain but without B's at 28.5-fold. Results We assembled a female genome and placed 53% of the sequence and 85% of the annotated proteins into specific chromosomes, by comparison with the 12 Drosophila genomes. Despite its very recent origin, the non-recombining neo-Y chromosome shows various signs of degeneration, including a significant enrichment of non-functional genes compared to the neo-X, and an excess of tandem duplications relative to other chromosomes. We also characterized a B-chromosome linked scaffold that contains an actively transcribed unit and shows sequence similarity to the subcentromeric regions of both the ancient X and the neo-X chromosome. Conclusions Our results provide novel insights into the very early stages of sex chromosome evolution and B chromosome origination, and suggest an unprecedented connection between the births of these two systems in D. albomicans.

  20. Nuclear-electrolytic hydrogen as a transportation fuel

    International Nuclear Information System (INIS)

    DeLuchi, M.A.

    1989-01-01

    Hydrogen is a very attractive transportation fuel in three important ways: it is the least polluting fuel that can be used in an internal combustion engine, it produces no greenhouse gases, and it is potentially available anywhere there is water and a clean source of power. The prospect of a clean, widely available transportation fuel has motivated much of the research on hydrogen fuels. This paper is a state-of-the art review of the production, storage, performance, environmental impacts, safety, and cost of nuclear-electrolytic hydrogen for highway vehicles

  1. Outsourcing drug discovery to India and China: from surviving to thriving.

    Science.gov (United States)

    Subramaniam, Swaminathan; Dugar, Sundeep

    2012-10-01

    Global pharmaceutical companies face an increasingly harsh environment for their primary business of selling medicines. They have to contend with a spiraling decline in the productivity of their R&D programs that is guaranteed to severely diminish their growth prospects. Outsourcing of drug discovery activities to low-cost locations is a growing response to this crisis. However, the upsides to outsourcing are capped by the failure of global pharmaceutical companies to take advantage of the full range of possibilities that this model provides. Companies that radically rethink and transform the way they conduct R&D, such as seeking the benefits of low-cost locations in India and China will be the ones that thrive in this environment. In this article we present our views on how the outsourcing model in drug discovery should go beyond increasing the efficiency of existing drug discovery processes to a fundamental rethink and re-engineering of these processes. Copyright © 2012. Published by Elsevier Ltd.

  2. Library Services For Neo-Literates: Some Challenges | Adjah ...

    African Journals Online (AJOL)

    It looks at the illiteracy situation in Ghana, and attempts made by the government to eradicate illiteracy by the establishment of the Non-Formal Education Division of the Ministry of Education, Science and Sports. The paper argues that libraries have an essential role to play to help neo-literates sustain literacy skills.

  3. The State of Denmark – Contested Neo-nationalisms

    DEFF Research Database (Denmark)

    Koefoed, Lasse Martin

    of this situation. The paper falls in three parts. First we as a background discuss the issue of nationalism in the light of current processes of globalization. Secondly, we turn to Denmark and explore the dominant discourses around neo-nationalism and the way in which they are constructed in relation to external...

  4. Decline of Meritocracy: Neo-Feudal Segregation in Turkey

    Science.gov (United States)

    Bagci, S. Erhan

    2015-01-01

    This paper claims that neo-liberalism is a period that capitalism calls and brings back some archaic forms of class domination depending on the results of marketisation policies in education. Marketisation policies in education are accompanied by specific shifts in ideological discourses, such as meritocracy that were valid only under the welfare…

  5. Genome-scale metabolic models as platforms for strain design and biological discovery.

    Science.gov (United States)

    Mienda, Bashir Sajo

    2017-07-01

    Genome-scale metabolic models (GEMs) have been developed and used in guiding systems' metabolic engineering strategies for strain design and development. This strategy has been used in fermentative production of bio-based industrial chemicals and fuels from alternative carbon sources. However, computer-aided hypotheses building using established algorithms and software platforms for biological discovery can be integrated into the pipeline for strain design strategy to create superior strains of microorganisms for targeted biosynthetic goals. Here, I described an integrated workflow strategy using GEMs for strain design and biological discovery. Specific case studies of strain design and biological discovery using Escherichia coli genome-scale model are presented and discussed. The integrated workflow presented herein, when applied carefully would help guide future design strategies for high-performance microbial strains that have existing and forthcoming genome-scale metabolic models.

  6. Comparative Education Research Framed by Neo-Institutional Theory: A Review of Diverse Approaches and Conflicting Assumptions

    Science.gov (United States)

    Wiseman, Alexander W.; Astiz, M. Fernanda; Baker, David P.

    2014-01-01

    The rise in globalisation studies in comparative education places neo-institutional theory at the centre of many debates among comparative education researchers. However, uncertainty about how to interpret neo-institutional theory still persists among educational comparativists. With this uncertainty comes misinterpretation of its principles,…

  7. Post-Chelyabinsk Risk Assessment for Near Earth Objects (NEOs)

    Science.gov (United States)

    Boslough, M.; Harris, A. W.

    2014-12-01

    The widely-accepted NEO risk assessments published in the 1990s concluded that the largest asteroids (> 1 km) dominated the hazard. Even though large NEOs represent only a tiny fraction of the population because of a power-law size distribution, the potential for global catastrophe means that the contribution from these low-probability, high-consequence events is large. This conclusion led to the Spaceguard survey, which has now catalogued about 90% of these objects, none of which is on a collision course. The survey has reduced the assessed risk from this size range by more than an order of magnitude because completion is highest for the largest and most dangerous. The relative risk from objects tens of meters in diameter is therefore increasing.The absolute assessed risk from airbursts caused by objects of this size is also higher for two reasons. First, they may be more frequent than previously thought because of an underestimated population. Second, they are significantly more damaging than assumed in the original assessment because (in most cases) they more efficiently couple energy to the surface than nuclear explosions. Last year's half-megaton airburst over Chelyabinsk, Russia, appears to challenge the notion that such events are extremely rare—especially when also considering the 1908 Tunguska event along with decades of infrasound bolide data showing higher-than-expected numbers of large airbursts.We will present a new analysis of the risk based on updated estimates for the population of undiscovered NEOs, taking into account the enhanced damage potential of collisional airbursts. Merging the survey population estimates with the bolide frequency estimates suggests a population of tens-of-meters sized bodies that may be a factor of three or so greater than estimated from surveys alone. Uncertainty in the population of airburst-class NEOs remains quite large, and can only be unambiguously reduced by expanded surveys focused on objects in the tens

  8. Stability and change in personality assessment: the revised NEO Personality Inventory in the year 2000.

    Science.gov (United States)

    Costa, P T; McCrae, R R

    1997-02-01

    The Revised NEO Personality Inventory (NEO-PI-R) consists of 30 facet scales that define the broad domains of the Five-Factor Model of personality. No major revisions of the basic model are anticipated in the near future. Despite their popularity, social desirability and inconsistency scales will not be added to the NEO-PI-R because their validity and utility have not yet been demonstrated. Among possible changes are minor modifications in wording and more extensive adaptations for adolescents and for populations with low reading levels. Contextualized (e.g., work-related) versions of the instrument will be further explored. Many changes are more easily implemented on the computer than the print version of the instrument.

  9. Status and prospects from the LHC

    International Nuclear Information System (INIS)

    Hawkings, Richard

    2010-01-01

    This article reviews the status of the CERN Large Hadron Collider and associated experiments as of July 2010. After a brief discussion of the progress in accelerator and experiment commissioning, the LHC physics landscape is presented, together with a selection of the experimental results achieved so far. Finally the prospects for the 2010-11 LHC physics run are reviewed, with an emphasis on possible discoveries in the Higgs and supersymmetry sectors.

  10. La cerámica impresa del neolítico inicial en el Mediterráneo occidental

    Directory of Open Access Journals (Sweden)

    Manuel PELLICER CATALÁN

    2009-10-01

    Full Text Available El conocimiento del neolítico en el Mediterráneo se desarrolló en un tiempo relativamente reciente. Su estudio comienza en el pasado siglo acentuándose a partir de la primera guerra mundial. En la segunda guerra y después de ella da un gran impulso con Bernabò Brea, con sus excavaciones en la cueva ligur de Arene Candide y en las Islas Eolias, con lo que estructura este complejo cultural en el Mediterráneo. En las directrices tomadas han sido de gran interés las aportaciones de Evans con sus conocimientos del Mediterráneo central, de Tarradell, buen conocedor del Norte de Africa y de Jodin. La nueva orientación de los estudios del neolítico mediterráneo son la consecuencia del conocimiento de yacimientos nuevos, del abandono del impuesto prejucio africanista y de una visión más amplia y objetiva del problema.

  11. Neo-Extractivism in Latin America – one side of a new phase of global capitalist dynamics

    Directory of Open Access Journals (Sweden)

    Ulrich Brand

    2016-01-01

    Full Text Available The aim of this text is to make sense of the emerging political-institutional, territorial, and socio-ecological dynamics and contradictions of neo-extractivism in Latin America in the context of global capitalist development. In contrast to some existing literature, we argue that the term ‘neo-extractivism’ should not be restricted to countries with progressive governments but be applied to all Latin American societies that, since the 1970s and especially since the year 2000, depend predominantly on the exploitation and exportation of nature. We argue that the often vague usage of the term neo-extractivism can be strengthened when it is seen in line with dominant development models. Therefore we refer to regulation theory and its historical heuristic of different phases of capitalist development. This enables us to look at the temporal-spatial interdependencies between shifting socio-economic and technological developments, world market structures, and political-institutional configurations that characterize neo-extractivism across scales and beyond national borders.

  12. Los pliegues cutáneos como predictores del porcentaje graso en futbolistas profesionales

    OpenAIRE

    Arruda, M.; Cossio-Bolaños, M.A.; Portella, D.

    2009-01-01

    El objetivo del presente estudio fue determinar los pliegues cutáneos que mejor predicen el porcentaje de grasa de futbolistas profesionales Peruanos a partir de tres ecuaciones. Para lo cual, se estudiaron 136 futbolistas profesionales evaluándose el peso corporal (kg), la estatura (m) y los pliegues cutáneos (mm) tricipital, subescapular, suprailiaco, abdominal, muslo y pantorrilla. Los resultados fueron analizados a través de la estadística descriptiva de la media aritmética (X) y desviaci...

  13. THE INTELLIGIBLE TRIAD IN NEO-PLATONISM AND PATRISTICS

    Directory of Open Access Journals (Sweden)

    A. FOKIN

    2011-10-01

    Full Text Available The author attempts to better defi ne the concept of the so-called «intelligible Triad» (esse, vivere, intellegere in Neo-Platonism and the Fathers of the Church. In the fi rst section, he explores the origins of this doctrine in Plato’s dialogue «Sophistes» as well as in the twelfth book of Aristotle’s «Metaphysics». This idea is also apparent in the doctrine concerning the distinct levels of being and the faculties of the human soul, a concept common to various Greek philosophical schools. The larger section of the article provides a reconstruction of the basic features and the elements of this theory of the «intelligible Triad» in the Neo-Platonic philosophy of Plotinus, Porphyry, Iamblichus, Syrianus, and Proclus, as well as in the diff erent Gnostic schools. Finally, the author raises the question of how this concept was employed and transformed by the Church Fathers. This will be the topic of the section of the article to follow.

  14. European Union’s integration issues after the rejection of the Constitutional Treaty. A Neo-Gramscian anaylsis (I

    Directory of Open Access Journals (Sweden)

    Anca Mădălina BONCILĂ

    2014-02-01

    Full Text Available Through this paper we have tried to question the reality of EU’ s integration and to identify the factors that shaped it. The complexity of this process led to multiple perspectives of analyzing it. We believe that Neo- Gramscian theory of European integration, although not so well-known, can be considered the most appropriate methodological support in explaining the events that have redefined the European integration: the rejection of the Constitutional Treaty, the financial crisis and the emergence of the Lisbon Treaty. We started from the assumption that the EU has obvious neo-liberal connotations, which led to the emergence of functional obstacles difficult to overcome, especially when it comes to the social dimension of the EU. Therefore, we divided the work into two basic parts, the first explains the methodology used, the main concepts, what neo-liberalism is and which are the EU’ s neo-liberal expressions and in the second part we focused on the social dimension of the EU, talking about the lack of substance that we found in the rhetoric of Fundamental Rights. Using the trade unions we have exemplified the inability of the EU to cope with social challenges, especially since there are forms of skepticism focused strictly on social discontent. The conclusions confirm that the Neo-Gramscian theory is the most suitable methodological support in an attempt to capture the nuances of EU’ s neo-liberal expressions.

  15. Accelerated pseudogenization on the neo-X chromosome in Drosophila miranda

    KAUST Repository

    Nozawa, Masafumi; Onizuka, Kanako; Fujimi, Mai; Ikeo, Kazuho; Gojobori, Takashi

    2016-01-01

    Y chromosomes often degenerate via the accumulation of pseudogenes and transposable elements. By contrast, little is known about X-chromosome degeneration. Here we compare the pseudogenization process between genes on the neo-sex chromosomes

  16. Neo-liberal transitions in nature policies in the Netherlands

    NARCIS (Netherlands)

    Kamphorst, D.A.; Coninx, I.

    2016-01-01

    In 2010, the national government made drastic changes in nature policy in the Netherlands. The choices they made appeared to reflect a neo-liberal ideology, given the strong emphasis on private responsibility and limited governmental interference in nature policy. One of the changes was further

  17. Neo: an object model for handling electrophysiology data in multiple formats

    Directory of Open Access Journals (Sweden)

    Samuel eGarcia

    2014-02-01

    Full Text Available Neuroscientists use many different software tools to acquire, analyse and visualise electrophysiological signals. However, incompatible data models and file formats make it difficult to exchange data between these tools. This reduces scientific productivity, renders potentially useful analysis methods inaccessible and impedes collaboration between labs.A common representation of the core data would improve interoperability and facilitate data-sharing.To that end, we propose here a language-independent object model, named Neo, suitable for representing data acquired from electroencephalographic, intracellular, or extracellular recordings, or generated from simulations. As a concrete instantiation of this object model we have developed an open source implementation in the Python programming language.In addition to representing electrophysiology data in memory for the purposes of analysis and visualisation, the Python implementation provides a set of input/output (IO modules for reading/writing the data from/to a variety of commonly used file formats.Support is included for formats produced by most of the major manufacturers of electrophysiology recording equipment and also for more generic formats such as MATLAB.Data representation and data analysis are conceptually separate: it is easier to write robust analysis code if it is focused on analysis and relies on an underlying package to handle data representation.For that reason, and also to be as lightweight as possible, the Neo object model and the associated Python package are deliberately limited to representation of data, with no functions for data analysis or visualisation.Software for neurophysiology data analysis and visualisation built on top of Neo automatically gains the benefits of interoperability, easier data sharing and automatic format conversion; there is already a burgeoning ecosystem of such tools. We intend that Neo should become the standard basis for Python tools in

  18. Neo-industrialization of Kuzbass economy in innovative development of coal industry and machinery

    Directory of Open Access Journals (Sweden)

    Balabanova Anna

    2017-01-01

    Full Text Available As part of rental-resource model and access restrictions to capital and new technologies, the attempts to encourage import substitution made by the government do not generate innovative type of economic development and reconstruction of economy’s manufacturing industry competitive on the domestic market. In conditions of searching for a new model of Russian economy development the analysis of a number of problems such as industry degradation, reducing the competitiveness of Russian producers, the growth of structural imbalances and overcoming the negative macroeconomic trends becomes strategically important. This raises the value of neo-industrialization as the integrator of resource security, scientific and industrial potential of Russian economy and high capacity of the domestic market in the innovative development system. A special role neo-industrialization plays for the economic development of old industrial regions, which include Kuzbass (Western Siberia, Russia. Neo-industrial development of Kuzbass economy should be initiated by the technological modernization of mining machinery and innovative development of coal industry.

  19. Lessons from Hot Spot Analysis for Fragment-Based Drug Discovery.

    Science.gov (United States)

    Hall, David R; Kozakov, Dima; Whitty, Adrian; Vajda, Sandor

    2015-11-01

    Analysis of binding energy hot spots at protein surfaces can provide crucial insights into the prospects for successful application of fragment-based drug discovery (FBDD), and whether a fragment hit can be advanced into a high-affinity, drug-like ligand. The key factor is the strength of the top ranking hot spot, and how well a given fragment complements it. We show that published data are sufficient to provide a sophisticated and quantitative understanding of how hot spots derive from a protein 3D structure, and how their strength, number, and spatial arrangement govern the potential for a surface site to bind to fragment-sized and larger ligands. This improved understanding provides important guidance for the effective application of FBDD in drug discovery. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. Superconductivity: 100th anniversary of its discovery and its future

    International Nuclear Information System (INIS)

    Kitazawa, Koichi

    2011-01-01

    The past and prospects of the superconducting technology are discussed as a systematic wide technology from the aspects of energy, transport and telecommunication. Superconductivity has unique characteristics, perpetual current, diamagnetism and Josephson effect. Since its discovery 100 years ago, it had taken nearly half a century to elucidate its mechanism and its application has still been restricted only to fields of extreme needs in the technical level. The major reason for the delay has apparently been the 'penalty of cooling', however, it is also due to the fact that a superconducting wire has to be a complex composite in a nanotechnology-processed structure. Also, owing to the discovery of high-temperature superconductors, it has recently become feasible to forecast a promising future of the superconducting technology in a long term. (author)

  1. Measuring Moral Thinking from a Neo-Kohlbergian Perspective

    Science.gov (United States)

    Thoma, Stephen J.

    2014-01-01

    The neo-Kohlbergian model revises and extends Lawrence Kohlberg's model of moral reasoning development to better reflect advances in research and theory. In moving from Kohlberg's global stage model to a multi-process description of moral functioning, these modifications are most evident in the ways in which moral thinking is described,…

  2. The unusual practices within some Neo-Pentecostal churches in South Africa: Reflections and recommendations

    Directory of Open Access Journals (Sweden)

    Mookgo S. Kgatle

    2017-09-01

    Full Text Available This article reflects and makes recommendations on the recent unusual practices within some Neo-Pentecostal churches in South Africa. Neo-Pentecostal churches in South Africa refer to churches that have crossed denominational boundaries. These churches idolise the miraculous, healing, deliverance and enactment of bizarre church performances often performed by charismatic and highly influential spiritual leaders. There have been unusual practices within some Neo-Pentecostal churches that include, among others, the eating of grass, eating of snakes, drinking of petrol, spraying of Doom on the congregants and other experiences. There are many possible theological, psychological and socio-economic explanations for these unusual practices. Given the facts that many South Africans experience various socio-economic challenges, it is argued here that the socio-economic factor is the main explanation for the support of these unusual practices. The unusual practices within some Neo-Pentecostal churches in South Africa are critically unpacked by looking at various churches where the incidents happened. The possible theological, psychological and socio-economic explanations for such practices are outlined in detail. Recommendations are made based on the scientific findings on the unusual practices.

  3. The Death of Georges Seurat: Neo-Impressionism and the Fate of the Avant-Garde in 1891

    Directory of Open Access Journals (Sweden)

    Young, Marnin

    2012-07-01

    Full Text Available This essay examines the critical and artistic responses to the death of Georges Seurat in 1891. While some at the time saw the avant-garde divided between scientifically-oriented neo-impressionism and mystical symbolism, the posthumous understanding of Seurat's work increasingly collapsed the two categories. In particular, the neo-impressionist embrace of the aesthetic of Charles Henry, in which compositional lines produced predictable effects on the viewer, made it possible to see Seurat's paintings in purely formal, indeed idealist, terms. The neo-impressionist avant-garde consequently struggled to define its distinctive nature over the course of the year, with important consequences for later art.

  4. The 40th anniversary of the discovery of NMR-chemical shift and nuclear spin-spin coupling

    International Nuclear Information System (INIS)

    Zhu Zhenghe; Gou Qingquan

    1989-01-01

    After the discovery of NMR Phenomenon in the physics laboratories of E.M.Purcell at Harvard and F.Bloch at Stanford in 1946, W.G.Proctor and F.C.Yu made the successful discovery of NMR-chemical shift and nuclear spin-spin coupling at Stanford in 1950, Which brought NMR spectroscopy from the physics laboratory to the laboratories of many different fields. This is worth memorizing. Retrospecting the past 40 years, it is sure that chemical shift theory will be much more prosperous prospects

  5. Estacionamientos subterráneos, en Madrid

    Directory of Open Access Journals (Sweden)

    López Saiz, J. M.

    1969-02-01

    Full Text Available Work on five underground parking sites in Madrid was initiated in September 1967. These parking sites were rented by the Madrid Town Council to the firm Estacionamientos Subterráneos, S. A. The engineering, design, and traffic and construction planning of these parking sites was allocated to Viales y Estacionamientos, S. A., whilst the actual construction was carried out by the firm Huarte y Cía., S. A. The five parking sites were located at the Paseo Calvo Sotelo, Plaza del Marqués de Salamanca, Plaza Mayor, Plaza de las Cortes and at Calle de Fuencarral, all within the centre of Madrid. These projects are of special interest, since each design represents an advance with respect to the earlier ones in regard to their structural and functional arrangements, with a view to achieving easier construction and less interference with road and pedestrian traffic. In the present article a description is given of each the five parking sites, following the sequence of their construction, which corresponds to the order in which they were design and planned.En septiembre de 1967 comenzaron las obras de cinco estacionamientos subterráneos en Madrid, adjudicadas por el Ayuntamiento en régimen de concesión a Estacionamientos Subterráneos, S. A. Los trabajos de ingeniería de tráfico, proyecto y control fueron encomendados a Viales y Estacionamientos, Sociedad Anteima (VIESA, y la ejecución de las obras se contrató con Huarte y Cía., S. A. Las ubicaciones de los estacionamientos cuya realización se comenta en este artículo son: Paseo de Calvo Sotelo, Plaza del Marqués de Salamanca - Plaza Mayor - Plaza de las Cortes - Calle de Fuencarral. Nos parece muy interesante exponer estas realizaciones, en las que se ve una clara evolución en su esquema estructural y la relación de éste con el esquema funcional, para lograr una mayor facilidad en la ejecución de las obras, junto con una interferencia mínima en superficie con los tráficos rodado y de

  6. Prospects for early SUSY searches at Lhc

    International Nuclear Information System (INIS)

    Borjanovic, I.

    2009-01-01

    Search for the physics beyond the Standard Model is one of the most relevant goals of the CMS and Atlas experiments at the Large Hadron Collider at CERN. Prospects for early R-parity conserving supersymmetry discovery and mass measurements with the CMS and Atlas detector for the first fb -1 of data are presented. All the presented studies are based on realistic Monte Carlo simulations.

  7. Status and prospects of safety research of fuel cycle facilities in France

    International Nuclear Information System (INIS)

    Auchere, H.; Mercier, J.P.

    1996-01-01

    The following themes of research are discussed: prolonged loss of cooling in concentrated fission product solution storage tanks; dewatering of a spent fuel storage pond; explosion risks in nuclear fuel cycle laboratories and plants; dissemination of radioactive materials in case of fire in fuel manufacturing plants and in spent fuel analysis laboratories; contamination transfer; phenomenology of liquid uranium hexafluoride vaporization into the atmosphere; ways and means of intervention in the event of liquid ClF 3 leakage; offsite explosion; seismic research. (K.A.)

  8. El concepto “backlash” en la europa neo-liberal

    Directory of Open Access Journals (Sweden)

    Giovanna Campani

    2015-10-01

    Full Text Available Derechos e igualdad de género progresan en una alternancia entre avances y retrocesos. El concepto de “backlash” -contragolpe- elaborado por la feminista norteamericana Susan Faludi en 1991, diez años después de la llegada al poder de los neo-conservadores, expresa bien la complejidad de las fases de los retrocesos. Este concepto puede ser muy útil hoy para analizar el contexto europeo, donde, mientras el ataque neo-liberal al sistema de bienestar está destruyendo la vida de millares de mujeres, y los recortes van bloqueando cualquier actividad de las asociaciones y las organizaciones non-gubernamentales de la sociedad civil, la Comisión Europea sigue anunciando un discurso de igualdad de género y hace recomendaciones e invita a los gobiernos a promover el empleo femenino, mientras la desocupación golpea al 50% de los jóvenes griegos, españoles e italianos.

  9. Physics of fusion-fuel cycles

    International Nuclear Information System (INIS)

    McNally, J.R. Jr.

    1981-01-01

    The evaluation of nuclear fusion fuels for a magnetic fusion economy must take into account the various technological impacts of the various fusion fuel cycles as well as the relative reactivity and the required β's and temperatures necessary for economic steady-state burns. This paper will review some of the physics of the various fusion fuel cycles (D-T, catalyzed D-D, D- 3 He, D- 6 Li, and the exotic fuels: 3 He 3 He and the proton-based fuels such as P- 6 Li, P- 9 Be, and P- 11 B) including such items as: (1) tritium inventory, burnup, and recycle, (2) neutrons, (3) condensable fuels and ashes, (4) direct electrical recovery prospects, (5) fissile breeding, etc. The advantages as well as the disadvantages of the different fusion fuel cycles will be discussed. The optimum fuel cycle from an overall standpoint of viability and potential technological considerations appears to be catalyzed D-D, which could also support smaller relatively clean, lean-D, rich- 3 He satellite reactors as well as fission reactors

  10. Trait-based assessment of borderline personality disorder using the NEO Five-Factor Inventory: Phenotypic and genetic support

    Science.gov (United States)

    Few, Lauren R.; Miller, Joshua D.; Grant, Julia D.; Maples, Jessica; Trull, Timothy J.; Nelson, Elliot C.; Oltmanns, Thomas F.; Martin, Nicholas G.; Lynskey, Michael T.; Agrawal, Arpana

    2015-01-01

    The aim of the current study was to examine the reliability and validity of a trait-based assessment of borderline personality disorder (BPD) using the NEO Five-Factor Inventory. Correlations between the Five-Factor Inventory-BPD composite (FFI-BPD) and explicit measures of BPD were examined across six samples, including undergraduate, community, and clinical samples. The median correlation was .60, which was nearly identical to the correlation between measures of BPD and a BPD composite generated from the full Revised NEO Personality Inventory (i.e., NEO-BPD; r =.61). Correlations between FFI-BPD and relevant measures of psychiatric symptomatology and etiology (e.g., childhood abuse, drug use, depression, and personality disorders) were also examined and compared to those generated using explicit measures of BPD and NEO-BPD. As expected, the FFI-BPD composite correlated most strongly with measures associated with high levels of Neuroticism, such as depression, anxiety, and emotion dysregulation, and the pattern of correlations generated using the FFI-BPD was highly similar to those generated using explicit measures of BPD and NEO-BPD. Finally, genetic analyses estimated that FFI-BPD is 44% heritable, which is comparable to meta-analytic research examining genetics associated with BPD, and revealed that 71% of the genetic influences are shared between FFI-BPD and a self-report measure assessing BPD (Personality Assessment Inventory – Borderline subscale; Morey, 1991). Generally, these results support the use of FFI-BPD as a reasonable proxy for BPD, which has considerable implications, particularly for potential gene-finding efforts in large, epidemiological datasets that include the NEO FFI. PMID:25984635

  11. FORAMINA OF THE POSTERIOR CRANIAL BASE: A STUDY OF ADULT INDIAN SKULLS. 89\tLas foraminas de la base posterior del cráneo: Un estudio en cráneos de indios adultos

    Directory of Open Access Journals (Sweden)

    Namita A Sharma

    2016-03-01

    Full Text Available Introducción: Las foraminas craneales son los únicos puntos de entrada a un cráneo que, de otra manera, permanecería cerrado. La evaluación de estas foraminas es una parte muy importante para el diagnóstico médico y debería ayudar al clínico en su  enfoque quirúrgico a esta delicada región. El presente estudio se centra en las foraminas de la base posterior del cráneo incluyendo los pares de fosas yugulares, el agujero estilomastoideo, el canal hipogloso; el impar agujero magno y otras foraminas auxiliares tales como el agujero mastoideo y el canal condíleo posterior. Material y Método: El estudio se llevo a cabo en 50 cráneos adultos, secos y macerados, pertenecientes todos ellos al subcontinente indio. Para ello se utilizó un calibre vernier con una precisión de 0.01 mm. Resultados: Se obtuvo una amplia variación en las dimensiones de la fosa yugular. La diferencia máxima bilateral en el mismo cráneo fue de 6.72 mm. La bóveda y la septación incompleta existían en un 20% de los cráneos. El tamaño del agujero estilomastoideo osciló entre 0.9-5.3 mm. Una de las 100 foraminas estudiadas se mostró estenosada. La duplicación se vio en el 4% de los cráneos. Las septaciones en el canal hipogloso se produjeron exclusivamente en el aspecto endocraneal y se observó bilateralmente en un 4% y unilateralmente en un 20% de los cráneos. En uno de los cráneos se encontró occipitalización del atlas. La salida del agujero magno estaba deformada y estenosada. Este fue el único cráneo con un índice en el agujero magno menor de 1. El agujero mastoideo  estuvo presente bilateralmente en un 74% y unilateralmente en un 16% de los cráneos, mientras que las cifras correspondientes para el  canal condíleo posterior fueron de 62% y 26% respectivamente. Introduction: Cranial foramina are the only portals to an otherwise closed cranium. Evaluation of these foramina is an important part of diagnostic medicine and would aid the

  12. Volatility Discovery

    DEFF Research Database (Denmark)

    Dias, Gustavo Fruet; Scherrer, Cristina; Papailias, Fotis

    The price discovery literature investigates how homogenous securities traded on different markets incorporate information into prices. We take this literature one step further and investigate how these markets contribute to stochastic volatility (volatility discovery). We formally show...... that the realized measures from homogenous securities share a fractional stochastic trend, which is a combination of the price and volatility discovery measures. Furthermore, we show that volatility discovery is associated with the way that market participants process information arrival (market sensitivity......). Finally, we compute volatility discovery for 30 actively traded stocks in the U.S. and report that Nyse and Arca dominate Nasdaq....

  13. Stem cells: a model for screening, discovery and development of drugs

    OpenAIRE

    Kitambi, Satish Srinivas; Chandrasekar, Gayathri

    2011-01-01

    Satish Srinivas Kitambi1, Gayathri Chandrasekar21Department of Medical Biochemistry and Biophysics; 2Department of Biosciences, Karolinska Institutet, Stockholm, SwedenAbstract: The identification of normal and cancerous stem cells and the recent advances made in isolation and culture of stem cells have rapidly gained attention in the field of drug discovery and regenerative medicine. The prospect of performing screens aimed at proliferation, directed differentiation, and toxicity and efficac...

  14. Políticas de calidad educativa en una sociedad NeoFeudal -El caso de Colombia-

    Directory of Open Access Journals (Sweden)

    Marco Fidel Zambrano Murillo

    2005-07-01

    Full Text Available Anclada en los enfoques clásicos de calidad, la política de calidad educativa colombiana promueve dos lógicas profundamente regresivas para las instituciones educativas: Por un lado una lógica NeoTaylorista para la enseñanza y por otro una lógica NeoFordista para el aprendizaje. Palabras clave: Política educativa, tradición, cultura.

  15. Large-Scale Urban Projects, Production of Space and Neo-liberal Hegemony: A Comparative Study of Izmir

    Directory of Open Access Journals (Sweden)

    Mehmet PENPECİOĞLU

    2013-04-01

    Full Text Available With the rise of neo-liberalism, large-scale urban projects (LDPs have become a powerful mechanism of urban policy. Creating spaces of neo-liberal urbanization such as central business districts, tourism centers, gated residences and shopping malls, LDPs play a role not only in the reproduction of capital accumulation relations but also in the shift of urban political priorities towards the construction of neo-liberal hegemony. The construction of neo-liberal hegemony and the role played by LDPs in this process could not only be investigated by the analysis of capital accumulation. For such an investigation; the role of state and civil society actors in LDPs, their collaborative and conflictual relationships should be researched and their functions in hegemony should be revealed. In the case of Izmir’s two LDPs, namely the New City Center (NCC and Inciraltı Tourism Center (ITC projects, this study analyzes the relationship between the production of space and neo-liberal hegemony. In the NCC project, local governments, investors, local capital organizations and professional chambers collaborated and disseminated hegemonic discourse, which provided social support for the project. Through these relationships and discourses, the NCC project has become a hegemonic project for producing space and constructed neo-liberal hegemony over urban political priorities. In contrast to the NCC project, the ITC project saw no collaboration between state and organized civil society actors. The social opposition against the ITC project, initiated by professional chambers, has brought legal action against the ITC development plans in order to prevent their implementation. As a result, the ITC project did not acquire the consent of organized social groups and failed to become a hegemonic project for producing space.

  16. The prospects of use of alternative types of fuel in road transport ...

    African Journals Online (AJOL)

    The article is devoted to the analysis of possibilities of using alternative types of fuel in transport. Gas engine fuels are considered as potential energy carriers for diesel engines. Since the constructions of vehicles, using gas and traditional types of fuel, have some differences, the most important are the issues of ensuring ...

  17. IAEA activities in the back-end area of nuclear fuel cycle

    International Nuclear Information System (INIS)

    Fukuda, Kosaku

    1999-01-01

    This paper concerns recent outcomes from the IAEA's activities in the area of the nuclear fuel cycle, particularly focusing on the back-end of the fuel cycle. It includes spent fuel management, plutonium utilization and burnup credit. In the area of spent fuel management, worldwide prospects and status of the spent fuel arising, storage and reprocessing are presented. In the area of plutonium utilization worldwide, only MOX fuel fabrication is described. Finally, the worldwide status of the burnup credit implementation is described. (author)

  18. Hazardous fuel treatments, suppression cost impacts, and risk mitigation

    Science.gov (United States)

    Matthew P. Thompson; Michael S. Hand; Julie W. Gilbertson-Day; Nicole M. Vaillant; Darek J. Nalle

    2013-01-01

    Land management agencies face uncertain tradeoffs regarding investments in preparedness and fuels management versus future suppression costs and impacts to valued resources and assets. Prospective evaluation of fuel treatments allows for comparison of alternative treatment strategies in terms of socioeconomic and ecological impacts, and can facilitate tradeoff analysis...

  19. A refined characterisation of the NeoHepatocyte phenotype necessitates a reappraisal of the transdifferentiation hypothesis.

    Science.gov (United States)

    Riquelme, Paloma; Wundt, Judith; Hutchinson, James A; Brulport, Marc; Jun, Yu; Sotnikova, Anna; Girreser, Ulrich; Braun, Felix; Gövert, Felix; Soria, Bernat; Nüssler, Andreas; Clement, Bernd; Hengstler, Jan G; Fändrich, Fred

    2009-03-01

    Under certain culture conditions human peripheral blood monocytes may be induced to express phenotypic markers of non-haematopoietic lineages, including hepatocyte-defining traits. One such example, the NeoHepatocyte, was previously shown to express a broad panel of hepatocyte-like marker antigens and metabolic activities, both in vitro and following engraftment in the liver of immunodeficient mice. In this report, a refined description of NeoHepatocytes, with regard to their expression of xenobiotic-metabolising enzymes, morphology, hepatocyte marker expression and cell surface phenotype, is presented in comparison with human macrophages in defined states of activation. Contrary to prior assertions, it would seem more likely that NeoHepatocytes express particular hepatocyte-defining genes during a normal programme of macrophage differentiation rather than undergoing a process of transdifferentiation to become hepatocyte-like cells.

  20. A neo-Aristotelian notion of reciprocity: about civic friendship and (the troublesome character of) right judicial decisions

    NARCIS (Netherlands)

    van Domselaar, I.

    2013-01-01

    This chapter argues that a neo-Aristotelian approach can play a valuable role in accounting for reciprocity in adjudication. It can solve the central flaws that an "adjudication as applied moral theory" approach faces. In addition, the author asserts that a neo-Aristotelian approach to adjudication

  1. Overview of the uranium prospecting in Uruguay[Study of Uranium prospection in Uruguay]; Panorama de la prospeccion de Uranio en el Uruguay

    Energy Technology Data Exchange (ETDEWEB)

    Rossi, P; Vaz Chaves, N; Pirelli, H

    1985-07-01

    The report is about Uranium prospection in Uruguay by DINAMIGE experts. They were explained the radioactive properties elements in Uranium and its importance as a fuel oil for electric energy generation.

  2. Materials for solar fuels and chemicals.

    Science.gov (United States)

    Montoya, Joseph H; Seitz, Linsey C; Chakthranont, Pongkarn; Vojvodic, Aleksandra; Jaramillo, Thomas F; Nørskov, Jens K

    2016-12-20

    The conversion of sunlight into fuels and chemicals is an attractive prospect for the storage of renewable energy, and photoelectrocatalytic technologies represent a pathway by which solar fuels might be realized. However, there are numerous scientific challenges in developing these technologies. These include finding suitable materials for the absorption of incident photons, developing more efficient catalysts for both water splitting and the production of fuels, and understanding how interfaces between catalysts, photoabsorbers and electrolytes can be designed to minimize losses and resist degradation. In this Review, we highlight recent milestones in these areas and some key scientific challenges remaining between the current state of the art and a technology that can effectively convert sunlight into fuels and chemicals.

  3. Left Dislocation in North-Eastern Neo-Aramaic dialects | Khan ...

    African Journals Online (AJOL)

    The North-Eastern Neo-Aramaic (NENA) dialects, which are the focus of this paper, were spoken across a wide area encompassing northern Iraq, north-west Iran, south-eastern Turkey, Armenia and Georgia. In these spoken dialects a distinction should be made between two major types of Left Dislocation (LD) structures.

  4. Progress and prospects for phosphoric acid fuel cell power plants

    Energy Technology Data Exchange (ETDEWEB)

    Bonville, L.J.; Scheffler, G.W.; Smith, M.J. [International Fuel Cells Corp., South Windsor, CT (United States)

    1996-12-31

    International Fuel Cells (IFC) has developed the fuel cell power plant as a new, on-site power generation source. IFC`s commercial fuel cell product is the 200-kW PC25{trademark} power plant. To date over 100 PC25 units have been manufactured. Fleet operating time is in excess of one million hours. Individual units of the initial power plant model, the PC25 A, have operated for more than 30,000 hours. The first model {open_quotes}C{close_quotes} power plant has over 10,000 hours of operation. The manufacturing, application and operation of this power plant fleet has established a firm base for design and technology development in terms of a clear understanding of the requirements for power plant reliability and durability. This fleet provides the benchmark against which power plant improvements must be measured.

  5. The SDF-1–CXCR4 signaling pathway: a molecular hub modulating neo-angiogenesis

    Science.gov (United States)

    Petit, Isabelle; Jin, David; Rafii, Shahin

    2010-01-01

    Pro-angiogenic bone marrow (BM) cells include subsets of hematopoietic cells that provide vascular support and endothelial progenitor cells (EPCs), which under certain permissive conditions could differentiate into functional vascular cells. Recent evidence demonstrates that the chemokine stromal-cell derived factor-1 (SDF-1, also known as CXCL12) has a major role in the recruitment and retention of CXCR4+ BM cells to the neo-angiogenic niches supporting revascularization of ischemic tissue and tumor growth. However, the precise mechanism by which activation of CXCR4 modulates neo-angiogenesis is not clear. SDF-1 not only promotes revascularization by engaging with CXCR4 expressed on the vascular cells but also supports mobilization of pro-angiogenic CXCR4+VEGFR1+ hematopoietic cells, thereby accelerating revascularization of ischemic organs. Here, we attempt to define the multiple functions of the SDF-1–CXCR4 signaling pathway in the regulation of neo-vascularization during acute ischemia and tumor growth. In particular, we introduce the concept that, by modulating plasma SDF-1 levels, the CXCR4 antagonist AMD3100 acutely promotes, while chronic AMD3100 treatment inhibits, mobilization of pro-angiogenic cells. We will also discuss strategies to modulate the mobilization of essential subsets of BM cells that participate in neo-angiogenesis, setting up the stage for enhancing revascularization or targeting tumor vessels by exploiting CXCR4 agonists and antagonists, respectively. PMID:17560169

  6. Pattern recognition applied to uranium prospecting

    Energy Technology Data Exchange (ETDEWEB)

    Briggs, P L; Press, F [Massachusetts Inst. of Tech., Cambridge (USA). Dept. of Earth and Planetary Sciences

    1977-07-14

    It is stated that pattern recognition techniques provide one way of combining quantitative and descriptive geological data for mineral prospecting. A quantified decision process using computer-selected patterns of geological data has the potential for selecting areas with undiscovered deposits of uranium or other minerals. When a natural resource is mined more rapidly than it is discovered, its continued production becomes increasingly difficult, and it has been noted that, although a considerable uranium reserve may remain in the U.S.A., the discovery rate for uranium is decreasing exponentially with cumulative exploration footage drilled. Pattern recognition methods of organising geological information for prospecting may provide new predictive power, as well as insight into the occurrence of uranium ore deposits. Often the task of prospecting consists of three stages of information processing: (1) collection of data on known ore deposits; (2) noting any regularities common to the known examples of an ore; (3) selection of new exploration targets based on the results of the second stage. A logical pattern recognition algorithm is here described that implements this geological procedure to demonstrate the possibility of building a quantified uranium prospecting guide from diverse geologic data.

  7. CONNECTION OF THE NEO-TETHYAN OCEAN TO THE RISE OF ...

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. CONNECTION OF THE NEO-TETHYAN OCEAN TO THE RISE OF THE HIMALAYAN MOUNTAIN BELT. Talat Ahmad,. Department of Geology,. University of Delhi,. Delhi – 11 00 07. tahmad001@yahoo.co.in. Notes:

  8. Determination of rare-earths and other trace elements in neo proterozoic-neo paleozoic dykes from Ceara state, Brazil, by neutron activation analysis

    Energy Technology Data Exchange (ETDEWEB)

    Anjos, Rafael Martins dos; Figueiredo, Ana M.G., E-mail: rafael.anjos@usp.b, E-mail: anamaria@ipen.b [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil). Centro do Reator Nuclear de Pesquisas. Lab. de Analise por Ativacao com Neutrons; Cardoso, Gustavo Luan; Marques, Leila S., E-mail: leila@iag.usp.b [Universidade de Sao Paulo (IAG/USP), SP (Brazil). Inst. de Astronomia, Geofisica e Ciencias Atmosfericas

    2011-07-01

    Trace elements such as rare earths, U, Th, Ta, Ba and Hf can be very useful in petrogenetic studies of igneous and metamorphic rocks, giving information about the origin and evolution of magmas. Instrumental Neutron Activation Analysis (INAA) is an accurate and precise for trace element analysis in geological samples, and provides the information required for this kind of studies. In this study, rare earths and incompatible trace elements were determined by INAA in the geological reference materials GS-N and BE-N, to quality control, and for the investigation of acid dykes of neo proterozoic-neo paleozoic ages, which outcrop in the Medio Coreau and Ceara Central domains from the Borborema Province (Ceara State). The powdered samples (particle sizes less than 100 mesh), crushed by using a mechanical agate mortar grinder, were irradiated at the IEA-R1 nuclear reactor at IPEN-CNEN/SP, and the induced activity was measured by high resolution gamma-ray spectrometry. The accuracy and precision of the method were evaluated and preliminary results of dyke samples are presented. (author)

  9. Prospects for Future Collider Physics

    CERN Document Server

    Ellis, John

    2016-10-20

    One item on the agenda of future colliders is certain to be the Higgs boson. What is it trying to tell us? The primary objective of any future collider must surely be to identify physics beyond the Standard Model, and supersymmetry is one of the most studied options. it Is supersymmetry waiting for us and, if so, can LHC Run 2 find it? The big surprise from the initial 13-TeV LHC data has been the appearance of a possible signal for a new boson X with a mass ~750 GeV. What are the prospects for future colliders if the X(750) exists? One of the most intriguing possibilities in electroweak physics would be the discovery of non-perturbative phenomena. What are the prospects for observing sphalerons at the LHC or a future collider?

  10. Baltic Pathways from Liberal Trade Model to Neo-Mercantilism in the European Union

    Directory of Open Access Journals (Sweden)

    Viljar Veebel

    2015-09-01

    Full Text Available The economic progress of the Baltic States after the restoration of independence has been closely related to the liberal ideology and values of their economies: openness to investments, simple tax system and low tax burden, liberal trade policy, and flexible labour market. Unlike the Baltic States, some of their main partners in the European Union (EU have focused on promoting their economic growth by the neo-mercantilist way of expanding exports, supported by the economic structure of these countries exporting high technology and capital goods. As a result, when the Baltic States are expecting that in a broader context the other eu member states share the same vision of the liberal market economy, their motives have not been fully understood among their regional trade and cooperation partners. Current study will debate whether the practical implementation and needs of the European neo-mercantilism meet the economic and social needs of the Baltic States. Additionally, the study focuses on the question whether in practice the Baltic countries should be ready for the European neo-mercantilist project in upcoming years.

  11. Comparing two alternative measures of general personality in the assessment of psychopathy: a test of the NEO PI-R and the MPQ.

    Science.gov (United States)

    Gaughan, Eric T; Miller, Joshua D; Pryor, Lauren R; Lynam, Donald R

    2009-08-01

    This study examined the interrelations between two measures of personality, the Revised NEO Personality Inventory (NEO PI-R; P. T. Costa & R. R. McCrae, 1992) and the Multidimensional Personality Questionnaire (MPQ; Tellegen & Waller, 2008), and their relations with psychopathy in a sample of undergraduates. Results revealed good convergence between conceptually related personality traits; however, the NEO PI-R facets accounted for more variance in the MPQ subscales (mean R(2)=.49) than did MPQ subscales in NEO PI-R facets (mean R(2)=.35). Both accounted for substantial proportions of variance in psychopathy scores, although the NEO PI-R accounted for larger proportions and manifested greater incremental validity when using the broader domains of each measure; the differences decreased when the narrower facets/subscales were used. The results suggest that, although both measures assess psychopathy-related traits, the NEO PI-R provides a more complete description because of its assessment of interpersonal antagonism and the central role of this construct in psychopathy.

  12. The Areva Group back-end division - challenges and prospects

    International Nuclear Information System (INIS)

    2004-06-01

    This document presents the Areva Group back-end division challenges and prospects. Areva, a world nuclear industry leader, analyzes in this document, the high-profile mix of complementary activities of the nuclear energy industry, concerning the back-end division the full range of services for the end of the fuel cycle, the fuel cycle back-end markets, the economic and financial associated considerations. (A.L.B.)

  13. 100 years poliovirus: from discovery to eradication. A meeting report.

    Science.gov (United States)

    Skern, Tim

    2010-09-01

    Just over hundred years ago, Karl Landsteiner and Erwin Popper identified a virus, later termed poliovirus, as the causative agent of poliomyelitis. This groundbreaking discovery simultaneously provided the basis for the measures that today prevent the outbreaks of the terrible epidemics caused by poliovirus. In 1988, the WHO started its eradication program to eliminate the virus from the planet. The symposium celebrated the discovery of poliovirus and discussed our current state of knowledge of poliovirus biology. Prospects for the eradication program were evaluated, with particular emphasis being placed on why certain countries still have not succeeding in interrupting wild-type transmission of poliovirus. Discussion also centred on the role of inactivated poliovirus vaccines in the eradication program and the maintenance of a poliovirus-free world, whenever this goal should be achieved.

  14. Comparative effect of carotenoid complex from golden neo-life ...

    African Journals Online (AJOL)

    Summary: The immunomodulatory effect of Carotenoid complex from Golden Neo-Life Dynamite (GNLD) and carrot extracted Carotenoid was assessed using 24 albino Wistar rats. The rats were assigned to 4 groups of 6 rats each consisting of group 1(control group treated with distilled water), group 2 (treated with olive oil) ...

  15. The nuclear fuel cycle; Le cycle du combustible nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-05-01

    After a short introduction about nuclear power in the world, fission physics and the French nuclear power plants, this brochure describes in a digest way the different steps of the nuclear fuel cycle: uranium prospecting, mining activity, processing of uranium ores and production of uranium concentrates (yellow cake), uranium chemistry (conversion of the yellow cake into uranium hexafluoride), fabrication of nuclear fuels, use of fuels, reprocessing of spent fuels (uranium, plutonium and fission products), recycling of energetic materials, and storage of radioactive wastes. (J.S.)

  16. No evidence for neo-oogenesis may link to ovarian senescence in adult monkey.

    Science.gov (United States)

    Yuan, Jihong; Zhang, Dongdong; Wang, Lei; Liu, Mengyuan; Mao, Jian; Yin, Yu; Ye, Xiaoying; Liu, Na; Han, Jihong; Gao, Yingdai; Cheng, Tao; Keefe, David L; Liu, Lin

    2013-11-01

    Female germline or oogonial stem cells transiently residing in fetal ovaries are analogous to the spermatogonial stem cells or germline stem cells (GSCs) in adult testes where GSCs and meiosis continuously renew. Oocytes can be generated in vitro from embryonic stem cells and induced pluripotent stem cells, but the existence of GSCs and neo-oogenesis in adult mammalian ovaries is less clear. Preliminary findings of GSCs and neo-oogenesis in mice and humans have not been consistently reproducible. Monkeys provide the most relevant model of human ovarian biology. We searched for GSCs and neo-meiosis in ovaries of adult monkeys at various ages, and compared them with GSCs from adult monkey testis, which are characterized by cytoplasmic staining for the germ cell marker DAZL and nuclear expression of the proliferative markers PCNA and KI67, and pluripotency-associated genes LIN28 and SOX2, and lack of nuclear LAMIN A, a marker for cell differentiation. Early meiocytes undergo homologous pairing at prophase I distinguished by synaptonemal complex lateral filaments with telomere perinuclear distribution. By exhaustive searching using comprehensive experimental approaches, we show that proliferative GSCs and neo-meiocytes by these specific criteria were undetectable in adult mouse and monkey ovaries. However, we found proliferative nongermline somatic stem cells that do not express LAMIN A and germ cell markers in the adult ovaries, notably in the cortex and granulosa cells of growing follicles. These data support the paradigm that adult ovaries do not undergo germ cell renewal, which may contribute significantly to ovarian senescence that occurs with age. Copyright © 2013 AlphaMed Press.

  17. Uruguay minerals fuels

    International Nuclear Information System (INIS)

    Goso, H.

    1967-01-01

    In this report the bases for the development of the necessary works of prospection are exposed on mineral fuels of Uruguay. We have taken the set from: coal, lutitas bituminous, uranium, petroleum and disturbs. In all the cases we have talked about to the present state of the knowledge and to the works that we considered necessary to develop in each case

  18. Bringing fuel cells to reality and reality to fuel cells: A systems perspective on the use of fuel cells

    International Nuclear Information System (INIS)

    Saxe, Maria

    2008-10-01

    The hopes and expectations on fuel cells are high and sometimes unrealistically positive. However, as an emerging technology, much remains to be proven and the proper use of the technology in terms of suitable applications, integration with society and extent of use is still under debate. This thesis is a contribution to the debate, presenting results from two fuel cell demonstration projects, looking into the introduction of fuel cells on the market, discussing the prospects and concerns for the near-term future and commenting on the potential use in a future sustainable energy system. Bringing fuel cells to reality implies finding near-term niche applications and markets where fuel cell systems may be competitive. In a sense fuel cells are already a reality as they have been demonstrated in various applications world-wide. However, in many of the envisioned applications fuel cells are far from being competitive and sometimes also the environmental benefit of using fuel cells in a given application may be questioned. Bringing reality to fuel cells implies emphasising the need for realistic expectations and pointing out that the first markets have to be based on the currently available technology and not the visions of what fuel cells could be in the future. The results from the demonstration projects show that further development and research on especially the durability for fuel cell systems is crucial and a general recommendation is to design the systems for high reliability and durability rather than striving towards higher energy efficiencies. When sufficient reliability and durability are achieved, fuel cell systems may be introduced in niche markets where the added values presented by the technology compensate for the initial high cost

  19. Síndromes Neurocutáneos identificables por el Médico General Integral mediante examen físico

    Directory of Open Access Journals (Sweden)

    Odalys Salas San Juan

    Full Text Available Introducción: el Síndrome Neurocutáneo es el término general que se utiliza para referirse a determinados trastornos neurológicos. Constituye un grupo heterogéneo de desórdenes congénitos que afectan principalmente a las estructuras derivadas del neuroectodermo embrionario. Objetivo: caracterizar los hallazgos clínicos de los Síndromes Neurocutáneos identificables al examen físico por el Médico General Integral. Métodos: se realizó un trabajo de revisión donde se utilizaron métodos teóricos en el proceso de revisión de la bibliografía actualizada seleccionada, específicamente en el campo de la neurología, la dermatología y la genética. Resultados: las características clínicas de la Esclerosis Tuberosa, Neurofibromatosis Tipo 1, Tipo 2, Schwannomatosis y Enfermedad de Sturge-Weber (Sindromes Neurocutáneos se pueden identificar durante el examen físico. Conclusiones: el adecuado conocimiento por el Médico General Integral, de las características clínicas del síndrome neurocutáneo, considerando su heterogeneidad y expresividad clínica, permite realizar al examen físico el diagnóstico oportuno de la enfermedad, lo que favorece el manejo del paciente.

  20. Some conditions and prospects of transition to closed fuel cycle in Russia

    International Nuclear Information System (INIS)

    Lependin, A.V.; Oussanov, V.I.; Lependina, E.V.; Ioughai, S.V.

    2001-01-01

    Nuclear policy of Russia is based on the necessity of closure of nuclear fuel cycle. But at the same time schedule of such a going is not defined. In this study some conditions and possible time-frames of going the nuclear fuel cycle of Russia to closure are discussed. Naturally, the main condition is revival of Russian economy wherein nuclear power will turn to be necessary in a number of Russian regions. But the question is whether closure of nuclear cycle strategy will be implemented in the near future or nuclear power will develop based on open fuel cycle over a long period of time? at present economic circumstances in Russia has formed in such a way that economics of current projects is not favourable to going to closure of cycle due to high capital investment cost and low fuel component of costs, due to low cost of natural uranium. Ecological analysis performed within the framework of external cost model also does not suggest that closed cycle has essential advantages at present, but also in sight. The authors have considered a model including not only external costs but also total resources expenditures with long-term power development. In the framework of such a method it can be demonstrated that closed fuel cycle has some important advantages taking into account not only tasks of immediate future, but power development strategy for the period of 30-50 years. Under conditions of nuclear capacities increase (to 30-50 GW) limitation of cheap uranium resources available in Russia will assume a new significance. Approach of prices at the back-end stages of nuclear fuel cycle to West Europe level also will favour to going to a closed fuel cycle. More severe ecological requirements answering to a sustainable development concept also will make a contribution. Closure of fuel cycle can be significantly accelerated in the case of implementation of weapon plutonium utilization program. The factors mentioned above facilitate evenly to going to a closed nuclear fuel

  1. Directions and prospects of using low grade process fuel to produce alumina

    Directory of Open Access Journals (Sweden)

    О. А. Дубовиков

    2016-08-01

    Full Text Available Power consumption across the globe is constantly increasing for a variety of reasons: growing population, industrialization and fast economic growth. The most widespread gaseous fuel – natural gas – has the low production cost. It is 2-3 times cheaper than liquid fuel production and 6-12 times cheaper than coal production. When natural gas is transported to distances from 1.5 to 2.5 thousand km by the pipeline, its cost with account of transportation is 1.5-2 times less than the cost of coal and the fuel storage facilities are not needed. Plants powered by natural gas have the higher efficiency as compared to the plants operating on other types of fuel. They are easier and cheaper to maintain and are relatively simple in automation, thus enhancing safety and improving the production process flow, do not require complicated fuel feeding or ash handling systems. Gas is combusted with a minimum amount of polluting emissions, which adds to better sanitary conditions and environment protection. But due to depletion of major energy resources many experts see the future of the global energy industry in opportunities associated with the use of solid energy carriers. From the environmental perspective solid fuel gasification is a preferred technology. The use of synthetic gas was first offered and then put to mass scale by English mechanical engineer William Murdoch. He discovered a possibility to use gas for illumination by destructive distillation of bituminous coal. After invention of the gas burner by Robert Bunsen, the illumination gas began to be used as a household fuel. The invention of an industrial gas generator by Siemens brothers made it possible to produce a cheaper generator gas which became a fuel for industrial furnaces. As the calorific value of generator gas produced through gasification is relatively low compared to natural gas, the Mining University studied possibilities to use different types of low grade process fuel at the

  2. Enfisema subcutáneo en mano y antebrazo por aire comprimido

    Directory of Open Access Journals (Sweden)

    M. Klein

    2003-12-01

    Full Text Available Las lesiones cutáneas que se acompañan de crepitación sugieren la sospecha de infecciones causadas por gérmenes productores de gas. Las causas no infecciosas no son tan reconocidas y suelen tener buen pronóstico. Presentamos un paciente de 27 años que consultó por hinchazón de la mano y antebrazo izquierdo luego de sufrir una lesión cutánea punzante en un dedo, y de secar el área con aire comprimido. En el examen se comprobó un extenso enfisema subcutáneo desde la mano hasta el codo. Una radiografía reveló la presencia de gas subcutáneo en la mano y antebrazo. El enfisema subcutáneo desapareció en 48 horas. El enfisema subcutáneo es siempre un signo preocupante y casos benignos como este se deben considerar en el diagnóstico diferencial. La exposición de lesiones preexistentes a gases comprimidos (compresores y herramientas neumáticas, tubos de gases para distintos usos, armas de aire comprimido identifica la causa y evita eventuales procedimientos quirúrgicos innecesarios.Cutaneous injuries with crepitus suggest infections caused by gas forming organisms. The non infectious causes of subcutaneous emphysema are underrecognized, and are usually of good prognosis. A 27 year old man presented a swollen hand and forearm. He had suffered a small puncture wound in a finger. He had cleaned and dried the area briefly with compressed air, developing a fast swelling of this hand and forearm. At examination, we found extended subcutaneous emphysema in a radiography and observed subcutaneous air in the hand and forearm; 48 hs later there was no evidence of subcutaneous air. The presence of subcutaneous emphysema is always worrisome and such cases must be considered in the differential diagnosis. The exposition of preexistent wounds to compressed air sources (high pressure pneumatic tools, scuba compressed air tubes, compressed air guns identifies the cause and prevents unnecessary surgical interventions.

  3. Sobre as teorias do imperialismo contemporâneo: uma leitura crítica

    Directory of Open Access Journals (Sweden)

    Leonardo de Magalhães Leite

    2014-05-01

    Full Text Available A teoria marxista, através do imperialismo, tem um instrumento de caracterização e interpretação do capitalismo contemporâneo. Atualmente, diversas vertentes do campo marxista (e que se assumem enquanto tal utilizam o imperialismo em suas análises, seja através do termo neoimperialismo, novo imperialismo, imperialismo tardio, Império, globalização, neoliberalismo, ou, simplesmente, imperialismo. Desta forma, o objetivo deste artigo é analisar as interpretações marxistas do imperialismo contemporâneo e responder à questão: existe uma teoria contemporânea do imperialismo?

  4. Fotoenvelhecimento cutâneo: processo, produtos

    OpenAIRE

    Bento, Bruna Silva

    2015-01-01

    Dissertação para obtenção do grau de Mestre no Instituto Superior de Ciências da Saúde Egas Moniz A pele é o órgão que cobre todo o corpo humano. Pela sua natureza de interface entre o organismo e o meio ambiente, desempenha funções de proteção, sensoriais e de homeostasia. A exposição constante da pele a agentes oxidantes endógenos e ambientais que conduzem à ocorrência de stress oxidativo é indicado como o principal mecanismo de envelhecimento cutâneo. Alguns fatores indutores do envelhe...

  5. Extremism and Neo-Liberal Education Policy: A Contextual Critique of the Trojan Horse Affair in Birmingham Schools

    Science.gov (United States)

    Arthur, James

    2015-01-01

    This paper offers new insights into the effects of neo-liberal education policies on some Muslim majority schools in Birmingham. It critically reveals how the implementation of neo-liberal education policies, pursued by both Labour and Conservative Governments, has contributed to the failure of some mechanisms of school leadership and governance.…

  6. The Near Earth Object Scout Spacecraft: A Low Cost Approach to in-situ Characterization of the NEO Population

    Science.gov (United States)

    Koontz, Steven L.; Condon, Gerald; Graham, Lee; Bevilacqua, Ricardo

    2014-01-01

    In this paper we describe a micro/nano satellite spacecraft and a supporting mission profile and architecture designed to enable preliminary in-situ characterization of a significant number of Near Earth Objects (NEOs) at reasonable cost. The spacecraft will be referred to as the NEO Scout. NEO Scout spacecraft are to be placed in GTO, GEO, or cis-lunar space as secondary payloads on launch vehicles headed for GTO or beyond and will begin their mission after deployment from the launcher. A distinguishing key feature of the NEO scout system is to design the mission timeline and spacecraft to rendezvous with and land on the target NEOs during close approach to the Earth-Moon system using low-thrust/high- impulse propulsion systems. Mission feasibility and preliminary design analysis are presented along with detailed trajectory calculations. The use of micro/nano satellites in low-cost interplanetary exploration is attracting increasing attention and is the subject of several annual workshops and published design studies (1-4). The NEO population consists of those asteroids and short period comets orbiting the Sun with a perihelion of 1.3 astronomical units or less (5-8). As of July 30, 2013 10065 Near-Earth objects have been discovered. The spin rate, mass, density, surface physical (especially mechanical) properties, composition, and mineralogy of the vast majority of these objects are highly uncertain and the limited available telescopic remote sensing data imply a very diverse population (5-8). In-situ measurements by robotic spacecraft are urgently needed to provide the characterization data needed to support hardware and mission design for more ambitious human and robotic NEO operations. Large numbers of NEOs move into close proximity with the Earth-Moon system every year (9). The JPL Near-Earth Object Human Space Flight Accessible Targets Study (NHATS) (10) has produced detailed mission profile and delta V requirements for various NEO missions ranging from 30

  7. Pneumomediastino espontâneo: Asma

    Directory of Open Access Journals (Sweden)

    Marcelo Cunha Fatureto

    2008-05-01

    Full Text Available Resumo: Pneumomediastino é definido como a presença de ar livre no mediastino, sendo que o espontâneo ocorre na ausência de enfermidades ou factores precipitantes. É raro em adultos, sendo mais frequente em recém-nascidos. Contudo, ocorre mais em adultos jovens, sendo 8:1 a relação entre homens e mulheres. Constitui achado raro na asma, representando 1% dos casos. Os sintomas mais frequentes são dor torácica e dispneia. O diagnóstico é feito com exames de imagem, como radiografia e tomografia computadorizada de tórax. O tratamento de escolha é conservador, não operatório, com prognóstico favorável na maioria dos casos. O nosso propósito é relatar um caso desta patologia em jovem atendido em nosso serviço com quadro de dor torácica e dispneia, sendo submetido a exames complementares e feito o diagnóstico de pneumomediastino espontâneo. O doente foi submetido a tratamento conservador com excelente evolução clínica. No momento encontrase assintomático, em acompanhamento ambulatorial.Rev Port Pneumol 2008; XIV (3: 437-441 Abstract: Pneumomediastinum is defined as the presence of free air in the mediastinum, and the spontaneous occurs in the absence of diseases or precipitating factors. It is rare in adults, and it is more frequent in new-borns. However, it occurs more in young adults, with an 8:1 relationship between men and women. It constitutes a rare finding in asthma, representing 1% of the cases. More frequent symptoms are chest pain and dyspnea. Diagnosis is made with image examinations, such as radiography and chest computed tomography. Treatment of choice is conservative, nonoperative, with a favourable prognosis in the majority of the cases. Our aim is to report a case of this pathology in a young adult seen in our service with chest pain and dyspnea. He underwent complementary examinations and the diagnosis was spontaneous pneumo-mediastinum. This patient

  8. Hot topics in alkaline exchange membrane fuel cells

    Science.gov (United States)

    Serov, Alexey; Zenyuk, Iryna V.; Arges, Christopher G.; Chatenet, Marian

    2018-01-01

    The tremendous progress from the first discovery of fuel cell principles by Sir William Robert Grove in 1839 [1] and independent observation of electricity generated in electrochemical reaction of hydrogen and air by a Swiss scientist Christian F. Shoenbein [2] to the recent breakthroughs in the fuel cell field resulted in the appearance of this clean energy technology around us. Indeed, fuel cell technology undoubtedly has entered into our life with the first introduction of Toyota Mirai Fuel Cell Vehicle (FCV) by Toyota Motor Co. in December of 2014 [3,4]. This FCV is commercially available and can be purchased in several countries. However, its sticker price of 57,500 substantially limits the number of customers that can purchase it. There are numerous factors that contribute to the high cost of fuel cell stack, however the price of platinum and platinum alloys is the main contributor [5].

  9. Nuclear fuel element and container

    International Nuclear Information System (INIS)

    Grubb, W.T.; King, L.H.

    1981-01-01

    The invention is based on the discovery that a substantial reduction in metal embrittlement or stress corrosion cracking from fuel pellet-cladding interaction can be achieved by the use of a copper layer or liner in proximity to the nuclear fuel, and an intermediate zirconium oxide barrier layer between the copper layer and the zirconium cladding substrate. The intermediate zirconia layer is a good copper diffusion barrier; also, if the zirconium cladding surface is modified prior to oxidation, copper can be deposited by electroless plating. A nuclear fuel element is described which comprises a central core of fuel material and an elongated container using the system outlined above. The method for making the container is again described. It comprises roughening or etching the surface of the zirconium or zirconium alloy container, oxidizing the resulting container, activating the oxidized surface to allow for the metallic coating of such surfaces by electroless deposition and further coating the activated-oxidized surface of the zirconium or zirconium alloy container with copper, iron or nickel or an alloy thereof. (U.K.)

  10. Construct redundancy within the Five-Factor Model as measured by the NEO PI-R: Implications for emotional intelligence and incremental coherence

    Directory of Open Access Journals (Sweden)

    GILLES E. GIGNAC

    2009-03-01

    Full Text Available Self-report measures of emotional intelligence (EI have been criticized for not being associated with unique validity, independently of comprehensive measures of personality such as the NEO PI-R. In this investigation, the issue of unique validity was re-directed at personality as measured by the facets of the NEO PI-R. Specifically, based on three samples, the personality facet of Depression within the NEO PI-R was found to be so substantially predicted by ten other NEO PI-R facets as to suggest construct redundancy within the NEO PI-R (i.e., R = .93, R = .99, R = .96. Because mixed-models of EI tend to be associated with clearer construct boundaries than personality, it is suggested that EI may be associated with some scientific utility (i.e., ‘incremental coherence’, even in the total absence of any empirically demonstrable unique validity.

  11. Conceptual Approach to Forming the Basic Code of Neo-Industrial Development of a Region

    Directory of Open Access Journals (Sweden)

    Elena Leonidovna Andreeva

    2017-09-01

    Full Text Available In the article, the authors propose the conceptual fundamentals of the “code approach” to the regional neo-industrial development. The purpose of the research is to reveal the essence of the transition to a new type of industrial and economic relations through a prism of “genetic codes” of the region. We consider these codes as a system of the “racial memory” of a territory, which determines the specificity and features of neo-industrialization realization. We substantiated the hypothesis about the influence of the “genetic codes” of the region on the effectiveness of the neo-industrialization. We have defined the participants, or else the carriers of the codes in the transformation of regional inheritance for the stimulation of the neoindustrial development of region’s economy. The subject matter of the research is the distinctive features of the functioning of the determinative region’s codes. Their content determines the socio-economic specificity of the region and the features of innovative, informational, value-based and competence-based development of the territory. The determinative codes generate the dynamic codes of the region, which are understood as their derivatives. They have a high probability of occurrence, higher speed of development and distribution, internal forces that make possible the self-development of the region. The scientific contribution is the substantiation of the basic code of the regional neo-industrial development. It represents the evolutionary accumulation of the rapid changes of its innovative, informational, value-based and competence-based codes stimulating the generation and implementation of new ideas regarding to economic entities adapted to the historical and cultural conditions. The article presents the code model of neo-industrial development of the region described by formulas. We applied the system analysis methods, historical and civilization approaches, evolutionary and

  12. Influence of ethnocentrism and neo-phobia on ethnic food consumption in Spain.

    Science.gov (United States)

    Camarena, Dena M; Sanjuán, Ana I; Philippidis, George

    2011-08-01

    Over the last decade, a strong upsurge in Spanish immigration has fostered a thriving ethnic food market. To examine indigenous consumer predilections toward ethnic foods, a carefully designed choice experiment is employed, with particular focus on ethnocentricity and food neo-phobia traits on potential purchase decisions. Employing a two level nested logit model, consumers choose to accept/reject ethnic foods, with a positive response met by a further series of different ethnic cuisine and consumption scenario alternatives. Bivariate tests reveal that higher ethnocentric and neo-phobic segments possess common socio-demographic characteristics, whilst neo-phobia plays a significantly stronger role in determining the probability of rejection. Further tests reveal culturally similar Mexican food as the preferred ethnic food across all consumption scenarios. Moreover, the 'restaurant' is the favoured format of consumption, whilst there is evidence of a strong association between specific ethnic food types and consumption formats. The implications of our research suggest that in the short to medium turn, price is a strong strategic variable, whilst marketing strategies must successfully isolate and exploit specific 'ethnic food/consumption scenario' mixes. Finally, stronger messages emphasizing quality and convenience factors are seen as key to bolstering the underrepresented 'home preparation' ethnic food market in Spain. Copyright © 2011 Elsevier Ltd. All rights reserved.

  13. Bio-fuels of the first generation

    International Nuclear Information System (INIS)

    2012-04-01

    After having briefly recalled the objective of use of renewable energies and the role bio-fuels may play, this publication briefly presents various bio-fuels: bio-diesel (from colza, soybean or sunflower oil), and ethanol (from beet, sugar cane, wheat or corn). Some key data regarding bio-fuel production and use in France are briefly commented. The publication outlines strengths (a positive energy assessment, a decreased dependency on imported fossil fuels and a higher supply safety, a diversification of agriculture revenues and prospects, a reduction of greenhouse gas emissions) and weaknesses (uncertainty regarding the evolution of soil use, an environmental impact related to farming methods) of this sector. Actions undertaken by the ADEME in collaboration with other agencies and institutions are briefly overviewed

  14. Frecuencia de grupos sanguíneos y factor Rh en donantes de sangre, Colombia ,1996

    Directory of Open Access Journals (Sweden)

    Mauricio Beltrán

    1999-03-01

    Full Text Available El establecer un patrón nacional de distribución de los grupos sanguíneos por seccionales de salud con base en los datos de donantes de banco de sangre, permite la localización e intercambio de sangre y componentes con fines de transfusión de una manera oportuna, mejora la disponibilidad de sangre y ofrece, además, información útil para áreas como las de genética para identificación personal y pruebas de paternidad, y en el campo antropológico para hallar diferencias raciales según su distribución. Con el fin de estimar la frecuencia y distribución de los grupos A, 8, AB y O y factor Rh por seccionales de salud en donantes de sangre, se analizó la información enviada durante 1996 por todos los bancos del país a la Coordinación Nacional de Bancos de Sangre con sede en el lnstituto Nacional de Salud. Se realizó un estudio descriptivo de la información, diferenciando por grupos sanguíneos y la presencia o ausencia del factor Rhesus. Durante 1996, los 180 bancos de sangre del país recolectaron 393.063 unidades de sangre; éstos reportaron los datos de pruebas de grupos sanguíneos A, B, AB , O y factor Rhesus de 338.063 (86% unidades; no se obtuvo información de las unidades restantes. Del total de unidades hemoclasificadas, 91,16% correspondió al factor Rhesus positivo; para este factor, la distribución por grupos sanguíneos fue de 56,2% para el grupo 0; 26,0% para el grupo A; 7,3% para el grupo B, y 1,4% para el grupo sanguíneo AB. El 8,83% de las unidades de sangre restantes correspondió al factor Rhesusne-a ativo. con una distribución por grupos sanguíneos de 5,1%'para el grupo 0; 2,7% para el grupo A; 0,7% para el grupo B, y para el grupo AB 0,31%. Los bancos de sangre de las seccionales de Antioquia, Caldas y San Andrés, reportaron la mayor proporción de unidades de sangre hemoclasificadas como factor Rhesus negativo. Esta información debe ser utilizada por todos los bancos de sangre, para ubicar e

  15. Nuclear fuel: sustainable source of energy or burden on society?

    International Nuclear Information System (INIS)

    Williams, T.; Klaiber, G.

    2007-01-01

    In the past, the question concerning the sustainability of a resource primarily addressed its finite nature. Accordingly, electricity production using renewable energies was clearly sustainable. Contrasting this are systems based on oil, gas, coal or uranium. However, from the perspective of 'neo-sustainability' being analyzed today, this assessment appears less clear-cut, especially in light of the definition of sustainability as provided by the Brundtland report. Nowadays, the depletion time of fuel resources is thus not the only significant aspect, but factors such as efficiency, ecofriendliness and social responsibility also figure in. The nuclear fuel supply is analyzed from a sustainability perspective. After a short description of the supply chain, each of the most important aspects of sustainability are related to the individual stages of the supply chain and evaluated. This method aims at answering the question concerning to what extent nuclear fuel is a sustainable source of energy. Although the recycling of fissile materials from reprocessing and the deployment of advanced reactors are key factors as regards the issue of sustainability, these topics are deliberately only touched on. The main focus lies on the sustainability of the nuclear fuel cycle as it is currently utilized in light water reactors, without discussing the subject of reprocessing. (orig.)

  16. Liposucción en Cirugía Reparadora (desengrasamiento de colgajos cutáneos y miocutáneos, exéresis de acúmulos grasos y autotransplante de grasa

    Directory of Open Access Journals (Sweden)

    J.Mª Serra Renom

    2013-12-01

    Full Text Available La liposucción es una técnica quirúrgica de gran utilidad para la remodelación de acúmulos grasos y para el desgrasamiento de los colgajos cutáneos, miocutáneos o musculares. Para el desgrasamiento de los colgajos la realizamos después del año de efectuado el colgajo. También la empleamos en acúmulos grasos, en la reconstrucción mamaria postmastectomía, y acúmulos grasos periféricos en la reducción mamaria. Igualmente en el tratamiento de cicatrices deprimidas con prominencia de tejidos vecinos. En zonas deprimidas la realización del autotransplante de grasa nos ha dado buenos resultados.

  17. Data Prospecting Framework - a new approach to explore "big data" in Earth Science

    Science.gov (United States)

    Ramachandran, R.; Rushing, J.; Lin, A.; Kuo, K.

    2012-12-01

    Due to advances in sensors, computation and storage, cost and effort required to produce large datasets have been significantly reduced. As a result, we are seeing a proliferation of large-scale data sets being assembled in almost every science field, especially in geosciences. Opportunities to exploit the "big data" are enormous as new hypotheses can be generated by combining and analyzing large amounts of data. However, such a data-driven approach to science discovery assumes that scientists can find and isolate relevant subsets from vast amounts of available data. Current Earth Science data systems only provide data discovery through simple metadata and keyword-based searches and are not designed to support data exploration capabilities based on the actual content. Consequently, scientists often find themselves downloading large volumes of data, struggling with large amounts of storage and learning new analysis technologies that will help them separate the wheat from the chaff. New mechanisms of data exploration are needed to help scientists discover the relevant subsets We present data prospecting, a new content-based data analysis paradigm to support data-intensive science. Data prospecting allows the researchers to explore big data in determining and isolating data subsets for further analysis. This is akin to geo-prospecting in which mineral sites of interest are determined over the landscape through screening methods. The resulting "data prospects" only provide an interaction with and feel for the data through first-look analytics; the researchers would still have to download the relevant datasets and analyze them deeply using their favorite analytical tools to determine if the datasets will yield new hypotheses. Data prospecting combines two traditional categories of data analysis, data exploration and data mining within the discovery step. Data exploration utilizes manual/interactive methods for data analysis such as standard statistical analysis and

  18. Astrometric Results of NEOs from the Characterization and Astrometric Follow-up Program at Adler Planetarium

    Science.gov (United States)

    Nault, Kristie A.; Brucker, Melissa J.; Hammergren, Mark; Gyuk, Geza; Solontoi, Mike R.

    2015-11-01

    We present astrometric results of near-Earth objects (NEOs) targeted in fourth quarter 2014 and in 2015. This is part of Adler Planetarium’s NEO characterization and astrometric follow-up program, which uses the Astrophysical Research Consortium (ARC) 3.5-m telescope at Apache Point Observatory (APO). The program utilizes a 17% share of telescope time, amounting to a total of 500 hours per year. This time is divided up into two hour observing runs approximately every other night for astrometry and frequent half-night runs approximately several times a month for spectroscopy (see poster by M. Hammergren et. al.) and light curve studies (see poster by M. J. Brucker et. al.).Observations were made using Seaver Prototype Imaging Camera (SPIcam), a visible-wavelength, direct imaging CCD camera with 2048 x 2048 pixels and a field of view of 4.78’ x 4.78’. Observations were made using 2 x 2 binning.Special emphasis has been made to focus on the smallest NEOs, particularly around 140m in diameter. Targets were selected based on absolute magnitude (prioritizing for those with H > 25 mag to select small objects) and a 3σ uncertainty less than 400” to ensure that the target is in the FOV. Targets were drawn from the Minor Planet Center (MPC) NEA Observing Planning Aid, the JPL What’s Observable tool, and the Spaceguard priority list and faint NEO list.As of August 2015, we have detected 670 NEOs for astrometric follow-up, on point with our goal of providing astrometry on a thousand NEOs per year. Astrometric calculations were done using the interactive software tool Astrometrica, which is used for data reduction focusing on the minor bodies of the solar system. The program includes automatic reference star identification from new-generation star catalogs, access to the complete MPC database of orbital elements, and automatic moving object detection and identification.This work is based on observations done using the 3.5-m telescope at Apache Point Observatory

  19. Aesthetic and semanticaccents of the neo-gothic interpretation in ...

    African Journals Online (AJOL)

    The relevance of the work is due to the need for a strategy of reconstruction of historic exterior and interior of architectural object located in a ruin condition with very limited factual information. The article considers specific features of the evolution of the neo-Gothic in the late XIX – early XX centuries in Russia. The stylistic ...

  20. Current status and prospects on Rokkasho nuclear fuel cycle project

    International Nuclear Information System (INIS)

    Suzuki, Mitsuo

    2003-01-01

    JNFL has been established aiming at fulfillment of Nuclear Fuel Cycle, as well as to contribute to the long-term and stable supply of nuclear power in Japan. 'Uranium Enrichment Plant' with its production of 1,050 SWU/y and planned to be expand to 1,500 SWU/y, 'Low Level Radioactive Waste Disposal Center' with 150,000/200 l drums stored, out of its 400,000 drums capacity, and 'Vitrified Waste Storage Center' with 760 canisters stored, out of its 1440 canisters capacity, are already in its operation. It is now preparing for the operation of '800 t/y Reprocessing Plant' and construction of '130t HM/y MOX Fuel Fabrication Plant'. As for the Reprocessing Plant, 780t of spent fuels has been already received and stored in the storage pools. Main plant is now in the course of test operation and planned to start the commercial operation by July 2006. Due to some defects found during the course of its construction, JNFL is now reviewing the Total Quality Assurance Structure to improve and reinforce its system. And for the MOX Fuel Fabrication Plant, activities towards obtaining the local autonomy's agreement for the construction are being made energetically. It is essential to obtain the good understanding of the public community to promote these projects successfully; JNFL is putting its best efforts to dispatch all the necessary information to the public in a timely manner. (author)

  1. Caminhos do pensamento neo-schumpeteriano: para além das analogias biológicas

    Directory of Open Access Journals (Sweden)

    Rosana Icassatti Corazza

    2004-01-01

    Full Text Available This paper aims at contributing to the discussion of the theoretical construction of the neo-Schumpeterian approach to technical and economic change. First, the fundamentals of this approach, based on analogies to evolutionary concepts of the biological sciences, are presented. Second, we show how neo-Schumpeterian thinking in recent literature has evolved beyond such analogies by integrating the concept of self-organization as the explanatory factor of the dynamic and evolving character of economic systems. Finally, some implications of the new perspective for the new-Schumpeterian research agenda are identified.

  2. Prospective use of the 3D printing technology for the microstructural engineering of Solid Oxide Fuel Cell components

    Energy Technology Data Exchange (ETDEWEB)

    Hernandez-Rodriguez, E. M.; Acosta-Mora, P.; Mendez-Ramos, J.; Borges Chinea, E.; Esparza Ferrera, P.; Canales-Vazquez, J.; Nunez, P.; Ruiz-Morales, J.

    2014-07-01

    A cost-effective micro-manufacturing process to accurately build 3D microstructures for their prospective use in the fabrication of Solid Oxide Fuel Cells components has been tested. The 3D printing method, based on the stereo lithography, allows solidifying layer by layer a dispersion of ceramic material in a liquid photosensitive organic monomer. A simple projector, a computer-controlled z-stage and a few PowerPoint slides may be used for the fabrication of a wide range of complex 3D microstructures in few minutes. In this work, 3D ceramic microstructures based on the yttria-stabilized zirconia (YSZ) were successfully fabricated. The micro structured ceramic components produced were stable after sintering at 1400 degree centigrade for 4 h. Impedance measurements show that the fabrication process does not have any detrimental effect on the electrical properties of the structured material. (Author)

  3. Prospective use of the 3D printing technology for the microstructural engineering of Solid Oxide Fuel Cell components

    International Nuclear Information System (INIS)

    Hernandez-Rodriguez, E. M.; Acosta-Mora, P.; Mendez-Ramos, J.; Borges Chinea, E.; Esparza Ferrera, P.; Canales-Vazquez, J.; Nunez, P.; Ruiz-Morales, J.

    2014-01-01

    A cost-effective micro-manufacturing process to accurately build 3D microstructures for their prospective use in the fabrication of Solid Oxide Fuel Cells components has been tested. The 3D printing method, based on the stereo lithography, allows solidifying layer by layer a dispersion of ceramic material in a liquid photosensitive organic monomer. A simple projector, a computer-controlled z-stage and a few PowerPoint slides may be used for the fabrication of a wide range of complex 3D microstructures in few minutes. In this work, 3D ceramic microstructures based on the yttria-stabilized zirconia (YSZ) were successfully fabricated. The micro structured ceramic components produced were stable after sintering at 1400 degree centigrade for 4 h. Impedance measurements show that the fabrication process does not have any detrimental effect on the electrical properties of the structured material. (Author)

  4. Prospects for supersymmetry discoveries at a 500 GeV e+e-collider

    International Nuclear Information System (INIS)

    Grivaz, J.F.

    1991-11-01

    The potential of a 500 GeV electron-positron collider for the discovery of supersymmetry is confirmed. If the MSSM is valid, at least one of its neutral Higgs bosons will be discovered. Moreover, the simultaneous observation of the three neutral Higgs bosons predicted by the model could decisively prove it. As shown by analyses incorporating realistic beam conditions and detector performances, charginos or scalar leptons can be discovered even close to the kinematic limit in spite of large standard model backgrounds, unless they are practically mass degenerate with the lightest neutralino. (author) 15 refs., 16 figs., 1 tab

  5. The coherence of life: A new physiology challenging (neo)Darwinism

    International Nuclear Information System (INIS)

    Jaeken, Laurent

    2009-01-01

    Schroedinger argued that coherent behaviour is one of the most remarkable properties of life. Despite this, it is one of the most neglected properties, studied only by a few groups of rather independent scientists in the domains of physiology but also of fundamental physics. In contrast, classical cell physiology, built on membrane theory, does not take coherent behaviour into account. Recently several independent approaches to the problem of coherence have been unified yielding a new paradigm for cell physiology, which can be derived from a non-linear Schroedinger equation. The new paradigm replaces outdated membrane theory. Similarly (neo)Darwinism is not firmly grounded on fundamental physics. However, during the eighties (neo)Darwinism was taken up in a broader theory of evolution, based on the non-linear equations of fundamental physics. It is argued here that life's coherent behaviour and the new physiology built on these coherent properties is directly compatible with the modern view on evolution, since both are based on the same principles of non-linearity.

  6. Energy solutions, neo-liberalism, and social diversity in Toronto, Canada.

    Science.gov (United States)

    Teelucksingh, Cheryl; Poland, Blake

    2011-01-01

    In response to the dominance of green capitalist discourses in Canada's environmental movement, in this paper, we argue that strategies to improve energy policy must also provide mechanisms to address social conflicts and social disparities. Environmental justice is proposed as an alternative to mainstream environmentalism, one that seeks to address systemic social and spatial exclusion encountered by many racialized immigrants in Toronto as a result of neo-liberal and green capitalist municipal policy and that seeks to position marginalized communities as valued contributors to energy solutions. We examine Toronto-based municipal state initiatives aimed at reducing energy use while concurrently stimulating growth (specifically, green economy/green jobs and 'smart growth'). By treating these as instruments of green capitalism, we illustrate the utility of environmental justice applied to energy-related problems and as a means to analyze stakeholders' positions in the context of neo-liberalism and green capitalism, and as opening possibilities for resistance.

  7. Energy Solutions, Neo-Liberalism, and Social Diversity in Toronto, Canada

    Science.gov (United States)

    Teelucksingh, Cheryl; Poland, Blake

    2011-01-01

    In response to the dominance of green capitalist discourses in Canada’s environmental movement, in this paper, we argue that strategies to improve energy policy must also provide mechanisms to address social conflicts and social disparities. Environmental justice is proposed as an alternative to mainstream environmentalism, one that seeks to address systemic social and spatial exclusion encountered by many racialized immigrants in Toronto as a result of neo-liberal and green capitalist municipal policy and that seeks to position marginalized communities as valued contributors to energy solutions. We examine Toronto-based municipal state initiatives aimed at reducing energy use while concurrently stimulating growth (specifically, green economy/green jobs and ‘smart growth’). By treating these as instruments of green capitalism, we illustrate the utility of environmental justice applied to energy-related problems and as a means to analyze stakeholders’ positions in the context of neo-liberalism and green capitalism, and as opening possibilities for resistance. PMID:21318023

  8. The world nuclear market and its prospects

    International Nuclear Information System (INIS)

    Anon.

    2010-07-01

    This market study of the nuclear industry presents: 1 - the dynamics of nuclear markets: organisation of the nuclear industry (fuel cycle, reactors), market analysis and key figures (uranium production, conversion and enrichment, fuel fabrication, reactor manufacturing, spent fuel reprocessing), strengths in presence and competition structure (companies ranking, market shares, positioning); 2 - nuclear renaissance and its basis: a suitable answer to the present day energy and environmental challenges (carbon-free energy and low volatility of fuel price), conjunction of favourable conditions (security of fuel supplies, political support, necessity of plants renewal), three main uncertainties (waste management, safety aspect, public opinion weight); 3 - perspectives of development at the 2030 prospects: data (scope of renaissance, market size), sector reconfiguration scenarios (evolution of competition, reconfiguration paths, concentration trend); 4 - analysis of the strategy of 13 companies, suppliers of the nuclear industry, with their key figures, positioning and strategy (production capacity, partnerships, external growth investments, new technical developments etc.). (J.S.)

  9. Natural gas for public and private transportation: Present situation and prospects

    International Nuclear Information System (INIS)

    Gambino, M.; Iannaccone, S.; Unich, A.

    1992-01-01

    In recent years, the use of natural gas as an automotive fuel for private and public vehicles has grown due to its interesting chemical-physical properties which make it an efficient fuel and more environmentally compatible than conventional fuels. This promising consumption trend has led to increased R ampersand D investments in attempts to enhance the fuel's automotive performance and exhaust emission characteristics. This paper reviews the advances in these directions which have been made thus far by research teams around the world and assesses commercialization prospects for natural gas automotive fuels in light of the more stringent air pollution regulations being proposed by the European Communities

  10. Reconstructing Plate Boundaries in the Jurassic Neo-Tethys From the East and West Vardar Ophiolites (Greece and Serbia)

    Science.gov (United States)

    Maffione, Marco; van Hinsbergen, Douwe J. J.

    2018-03-01

    Jurassic subduction initiation in the Neo-Tethys Ocean eventually led to the collision of the Adria-Africa and Eurasia continents and the formation of an 6,000 km long Alpine orogen spanning from Iberia to Iran. Reconstructing the location and geometry of the plate boundaries of the now disappeared Neo-Tethys during the initial moments of its closure is instrumental to perform more realistic plate reconstructions of this region, of ancient ocean basins in general, and on the process of subduction initiation. Neo-Tethyan relics are preserved in an ophiolite belt distributed above the Dinaric-Hellenic fold-thrust belt. Here we provide the first quantitative constraints on the geometry of the spreading ridges and trenches active in the Jurassic Neo-Tethys using a paleomagnetically based net tectonic rotation analysis of sheeted dykes and dykes from the West and East Vardar Ophiolites of Serbia (Maljen and Ibar) and Greece (Othris, Pindos, Vourinos, and Guevgueli). Based on our results and existing geological evidence, we show that initial Middle Jurassic ( 175 Ma) closure of the western Neo-Tethys was accommodated at a N-S trending, west dipping subduction zone initiated near and parallel to the spreading ridge. The West Vardar Ophiolites formed in the forearc parallel to this new trench. Simultaneously, the East Vardar Ophiolites formed above a second N-S to NW-SE trending subduction zone located close to the European passive margin. We tentatively propose that this second subduction zone had been active since at least the Middle Triassic, simultaneously accommodating the closure of the Paleo-Tethys and the back-arc opening of Neo-Tethys.

  11. Studies of neo-formed phases occurring during spent nuclear fuel dissolution in geological repository: influence of silicate ions

    International Nuclear Information System (INIS)

    Robit-Pointeau, V.

    2005-12-01

    Spent nuclear fuel alteration in deep storage conditions may proceed by local oxidising conditions at the fuel / water interface under influence of alpha irradiation. However, due to the strong redox buffer capacity of the near-field materials (especially the canister and the geological media), most of the near-field environment will remain reducing. Due to the relative high concentration in silica in such system, coffinite USiO 4 .n(H 2 O) may be a relevant phase to consider as it has been suggested from the natural analogues observations (Oklo). The aim of this work was to assess the relevance of coffinitisation of the spent fuel phenomena. The results of the experimental work contest the thermodynamic predictions. Instead of coffinite, a new U(IV)-Si phase has been observed in water simulating storage conditions. The thermodynamic data on coffinite validated by OECD are based on the average concentration of dissolved silica present in natural system containing uraninite and quartz. As the silica concentration in natural groundwaters is more probably controlled by minerals like chalcedony or silica gel, the coffinite present with uraninite in such systems, is probably not in equilibrium even in 2-billion years- old geological sites. Based on the results of this study, coffinitisation of the spent nuclear fuel in deep geological disposal is not anticipated to be a dominant short term process. (author)

  12. Hematoma epidural espinal espontâneo durante a gravidez: registro de um caso

    Directory of Open Access Journals (Sweden)

    Ivan Hack

    1984-03-01

    Full Text Available Registro de caso de paciente no oitavo mês de gestação que desenvolveu hematoma epidural espinal espontâneo dorsolombar. A gravidez, determinando aumento da pressão intra-abdominal e, como consequência, aumento da pressão venosa no plexo epidural, poderia ter sido o fator desencadeante no hematoma- A paciente foi submetida a cirurgia precocemente, porém não apresentou recuperação do déficit sensitivo-motor. São discutidos aspectos clínicos, do tratamento cirúrgico, da evolução e da etiologia dos hematomas epidurals espinais espontâneos.

  13. LINFOMA CUTÁNEO PRIMARIO DE CÉLULAS B, DEL TIPO DE LA PIERNA

    OpenAIRE

    BONILLA JARAMILLO, LINA MARÍA; CALDERÓN, JORGE ENRIQUE; JUAN GUILLERMO, CHALELA; GONZÁLEZ, MARÍA ISABEL

    2012-01-01

    El linfoma de células B del tipo de la pierna, es una neoplasia rara y agresiva, con características clínicas, morfológicas e inmunofenotípicas distintivas. Está clasificada dentro del grupo de linfomas cutáneos primarios de células B y se presenta en edades avanzadas, con predominio en mujeres y altas tasas de recurrencia. Presentamos el caso de una mujer de 63 años de edad, con diagnóstico clínico e inmunofenotípico de linfoma cutáneo de células B del tipo de la pierna. Primary cutaneous...

  14. A Comparison of Agreeableness Scores from the Big Five Inventory and the Neo PI-R: Consequences for the Study of Narcissism and Psychopathy

    Science.gov (United States)

    Miller, Joshua D.; Gaughan, Eric T.; Maples, Jessica; Price, Joanna

    2011-01-01

    Despite being significantly correlated, there is evidence to suggest that the scales measuring Agreeableness from the Big Five Inventory (BFI) and the Revised NEO Personality Inventory (NEO PI-R) do not capture identical constructs. More specifically, NEO PI-R Agreeableness contains content related to "honesty and humility" that is not…

  15. Stem cells: a model for screening, discovery and development of drugs.

    Science.gov (United States)

    Kitambi, Satish Srinivas; Chandrasekar, Gayathri

    2011-01-01

    The identification of normal and cancerous stem cells and the recent advances made in isolation and culture of stem cells have rapidly gained attention in the field of drug discovery and regenerative medicine. The prospect of performing screens aimed at proliferation, directed differentiation, and toxicity and efficacy studies using stem cells offers a reliable platform for the drug discovery process. Advances made in the generation of induced pluripotent stem cells from normal or diseased tissue serves as a platform to perform drug screens aimed at developing cell-based therapies against conditions like Parkinson's disease and diabetes. This review discusses the application of stem cells and cancer stem cells in drug screening and their role in complementing, reducing, and replacing animal testing. In addition to this, target identification and major advances in the field of personalized medicine using induced pluripotent cells are also discussed.

  16. Valiant, Independent, and Harmonious: Paul Signac and Neo-Impressionism after 1900

    Directory of Open Access Journals (Sweden)

    Dymond, Anne

    2012-07-01

    Full Text Available Through a close reading of Parisian art criticism around 1900, this essay examines Paul Signac's role as de facto head of the neo-impressionists and guiding spirit of the Salon des Indépendants. Signac, and the neo-impressionists generally, had suffered from the decline of the Indépendants in the latter 1890s, but the resurgence of both group and Salon in 1901 positioned Signac as one of the most significant avant-garde artists in the early 20th century, where he played a vital role in the most significant art debates then animating Paris. Their return to prominence was due in no small measure to Signac's latest foray into the decorative, a highly charged arena that would be central to the artistic debates of the first decade of the 20th century.

  17. Is Global Neo-Liberalism Shaping the Future of Physical Education?

    Science.gov (United States)

    Macdonald, Doune

    2014-01-01

    With claims that neo-liberalism is the "specific defining political/economic paradigm of the age in which we live?…?" [Apple, Michael. 2006. "Educating the 'Right' Way: Markets, Standards, God, and Inequality." New York: Taylor & Francis, 14.], an invited symposium at the 2012 International Convention on Science, Education…

  18. Route to neo-inguinal canal: Our experience

    Directory of Open Access Journals (Sweden)

    J Jacob Swaroop Anand

    2011-01-01

    Full Text Available Aim: The objective of this study was to stress the importance and value of this route to neo-inguinal canal creation for undescended testis management laparoscopically. Materials and Methods: Data from the Department of Paediatric Surgery, Coimbatore Medical College, was taken. Retrospective study was undertaken for the period 2004 to 2008. Here the surgical technique and outcome of the treatment are recorded for children aged 1 year to 12 years. Results: A total of 126 children underwent laparoscopic stage II surgery by this route (medial to the medial umbilical ligament. Right-sided undescended testis (UDT was present in 76 (60% patients. Left-sided UDT was present in 45 (35% patients. Bilateral UDT was present in 5 (5% patients. There were 90 (71% patients aged less than 2 years and 36 (29% patients aged more than 2 years. The eldest patient was 12 years of age. The overall hospital stay was 1 day. There were no complications seen in the follow-up. In all cases, the testis could not be brought down in a single stage. Conclusion: Creation of neo-inguinal canal medial to the medial umbilical ligament and just lateral to the bladder has the advantage of gaining more length on the vessels and vas to bring the testis to scrotum. The laparoscopic management of undescended testis in stage II by this innovative new route is simple, less complicated and well tolerated.

  19. Projection of fossil fuels consumption in the Venezuelan electricity generation industry

    International Nuclear Information System (INIS)

    Vidoza, Jorge A.; Gallo, Waldyr L.R.

    2016-01-01

    This study presents a prospective analysis on the impacts of recent efficient energy policies application in Venezuela, integrating both oil production and electricity supply to assess energy resources balance in a quantitative manner. A special focus is given to main fossil fuels used in the electric power industry; natural gas, diesel oil and fuel oil. Four scenarios were proposed, ranging from a low-economy-growth/low-efficiency scenario to an optimist high-economy-growth/high-efficiency scenario. Efficiency effects are more notorious for high-economy-growth case, fuel consumption for electricity generation reduces 38% for natural gas, 12% for diesel and 29% for fuel oil, in the established time period. Deficits in oil and gas Venezuelan production were also determined, deficits are highly affected by economical forecasting, and by fuel smuggling in Venezuelan borders. Results showed the high importance of energy efficiency policies development for Venezuela, in order to reduce fossil fuel domestic consumption to allocate them in a more profitable market. - Highlights: • We made a prospective analysis on efficient energy policies impacts in Venezuela. • Reduced fuel consumption was obtained for efficient scenarios. • Current energy regulations are not enough to encourage energy efficiency. • Hydroelectricity projects need more promotion to have deeper impacts.

  20. CONSTITUCIONALISMO LIBERAL CONTEMPORÁNEO VS DEMOCRACIA

    Directory of Open Access Journals (Sweden)

    Leonel Martínez Castro

    2012-12-01

    Full Text Available En las siguientes líneas, el autor reconstruye y analiza algunos fundamentos e instituciones relevantes del constitucionalismo liberal contemporáneo, con todas sus variaciones y cambios de tonalidad, para cuestionarle la ausencia de legitimidad democrática en su sistema normativista. Esta labor es realizada a partir de la crítica a las enunciaciones metafísicas, derechos universales y procedimientos normativos como elementos estructurantes del orden simbólico, que desplazan a las subjetividades políticas en la creación y construcción de su propia realidad.

  1. A review on the development of the advanced fuel fabrication technology

    International Nuclear Information System (INIS)

    Lee, Jung Won; Lee, Yung Woo; Sohn, Dong Sung; Yang, Myung Seung; Bae, Kee Kwang; Nah, Sang Hoh; Kim, Han Soo; Kim, Bong Koo; Song, Keun Woo; Kim, See Hyung

    1995-07-01

    In this state-of art report, the development status of the advanced nuclear fuel was investigated. The current fabrication technology for coated particle fuel and non-oxide fuel such as sol-gel technology, coating technology, and carbothermic reduction reaction has also been examined. In the view point of inherent safety and efficiency in the operation of power plant, the coated particle fuel will keep going on its reputation as nuclear fuel for a high temperature gas cooled reactor, and the nitride fuel is very prospective for the next liquid metal fast breeder reactor. 43 figs., 17 tabs., 96 refs. (Author)

  2. A review on the development of the advanced fuel fabrication technology

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jung Won; Lee, Yung Woo; Sohn, Dong Sung; Yang, Myung Seung; Bae, Kee Kwang; Nah, Sang Hoh; Kim, Han Soo; Kim, Bong Koo; Song, Keun Woo; Kim, See Hyung [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1995-07-01

    In this state-of art report, the development status of the advanced nuclear fuel was investigated. The current fabrication technology for coated particle fuel and non-oxide fuel such as sol-gel technology, coating technology, and carbothermic reduction reaction has also been examined. In the view point of inherent safety and efficiency in the operation of power plant, the coated particle fuel will keep going on its reputation as nuclear fuel for a high temperature gas cooled reactor, and the nitride fuel is very prospective for the next liquid metal fast breeder reactor. 43 figs., 17 tabs., 96 refs. (Author).

  3. Induction of Pro-Apoptotic Endoplasmic Reticulum Stress in Multiple Myeloma Cells by NEO214, Perillyl Alcohol Conjugated to Rolipram.

    Science.gov (United States)

    Chen, Thomas C; Chan, Nymph; Labib, Shirin; Yu, Jiali; Cho, Hee-Yeon; Hofman, Florence M; Schönthal, Axel H

    2018-01-17

    Despite the introduction of new therapies for multiple myeloma (MM), many patients are still dying from this disease and novel treatments are urgently needed. We have designed a novel hybrid molecule, called NEO214, that was generated by covalent conjugation of the natural monoterpene perillyl alcohol (POH), an inducer of endoplasmic reticulum (ER) stress, to rolipram (Rp), an inhibitor of phosphodiesterase-4 (PDE4). Its potential anticancer effects were investigated in a panel of MM cell lines. We found that NEO214 effectively killed MM cells in vitro with a potency that was over an order of magnitude stronger than that of its individual components, either alone or in combination. The cytotoxic mechanism of NEO214 involved severe ER stress and prolonged induction of CCAAT/enhancer-binding protein homologous protein (CHOP), a key pro-apoptotic component of the ER stress response. These effects were prevented by salubrinal, a pharmacologic inhibitor of ER stress, and by CHOP gene knockout. Conversely, combination of NEO214 with bortezomib, a drug in clinical use for patients with MM, resulted in synergistic enhancement of MM cell death. Combination with the adenylate cyclase stimulant forskolin did not enhance NEO214 impact, indicating that cyclic adenosine 3',5'-monophosphate (AMP) pathways might play a lesser role. Our study introduces the novel agent NEO214 as a potent inducer of ER stress with significant anti-MM activity in vitro. It should be further investigated as a potential MM therapy aimed at exploiting this tumor's distinct sensitivity to ER stress.

  4. Puzzle-solving in psychology : The neo-Galtonian vs. nomothetic research focuses

    NARCIS (Netherlands)

    Vautier, Stephane; Lacot, Emilie; Veldhuis, Michiel

    We compare the neo-Galtonian and nomothetic approaches of psychological research. While the former focuses on summarized statistics that depict average subjects, the latter focuses on general facts of form 'if conditions then restricted outcomes'. The nomothetic approach does not require

  5. Sentinel lymph node biopsy using dye alone method is reliable and accurate even after neo-adjuvant chemotherapy in locally advanced breast cancer - a prospective study

    Directory of Open Access Journals (Sweden)

    Mishra Ashwani

    2011-02-01

    Full Text Available Abstract Background Sentinel lymph node biopsy (SLNB is now considered a standard of care in early breast cancers with N0 axillae; however, its role in locally advanced breast cancer (LABC after neo-adjuvant chemotherapy (NACT is still being debated. The present study assessed the feasibility, efficacy and accuracy of sentinel lymph node biopsy (SLNB using "dye alone" (methylene blue method in patients with LABC following NACT. Materials and methods Thirty, biopsy proven cases of LABC that had received three cycles of neo-adjuvant chemotherapy (cyclophosphamide, adriamycin, 5-fluorouracil were subjected to SLNB (using methylene blue dye followed by complete axillary lymph node dissection (levels I-III. The sentinel node(s was/were and the axilla were individually assessed histologically. The SLN accuracy parameters were calculated employing standard definitions. The SLN identification rate in the present study was 100%. The sensitivity of SLNB was 86.6% while the accuracy was 93.3%, which were comparable with other studies done using dual lymphatic mapping method. The SLN was found at level I in all cases and no untoward reaction to methylene blue dye was observed. Conclusions This study confirms that SLNB using methylene blue dye as a sole mapping agent is reasonably safe and almost as accurate as dual agent mapping method. It is likely that in the near future, SLNB may become the standard of care and provide a less morbid alternative to routine axillary lymph node dissection even in patients with LABC that have received NACT.

  6. Radiation Grafted Polymer Membranes for Fuel Cell Applications

    International Nuclear Information System (INIS)

    Scherer, G.G.; Wallasch, F.; Ben Youcef, H.; Gubler, L.

    2012-01-01

    Partially fluorinated proton exchange membranes prepared via radiation induced graft copolymerization ('radiation grafting') offer the prospect of cost-effective and tailor made membrane electrolytes for the polymer electrolyte fuel cell (PEFC). The composition and structure of radiation grafted membranes can be adjusted in a broad range to balance the different requirements of proton transport and mechanical robustness. Based on the earlier work on Styrene grafting, the novel monomer combination α-methyl-styrene/methacrylonitrile (AMS/MAN) is introduced for improved stability in the prevailing fuel cell environment. Successful fuel cell experiments proved the concept. (author)

  7. Radiation Grafted Polymer Membranes for Fuel Cell Applications

    Energy Technology Data Exchange (ETDEWEB)

    Scherer, G G; Wallasch, F; Ben Youcef, H; Gubler, L [Electrochemistry Laboratory, Paul Scherrer Institut, CH-5232 Villigen (Switzerland)

    2012-09-15

    Partially fluorinated proton exchange membranes prepared via radiation induced graft copolymerization ('radiation grafting') offer the prospect of cost-effective and tailor made membrane electrolytes for the polymer electrolyte fuel cell (PEFC). The composition and structure of radiation grafted membranes can be adjusted in a broad range to balance the different requirements of proton transport and mechanical robustness. Based on the earlier work on Styrene grafting, the novel monomer combination {alpha}-methyl-styrene/methacrylonitrile (AMS/MAN) is introduced for improved stability in the prevailing fuel cell environment. Successful fuel cell experiments proved the concept. (author)

  8. A Neo-Piagetian Analysis of Communication Performance in Young Children.

    Science.gov (United States)

    Foorman, Barbara R.

    This exploratory study was conducted to interpret age and individual differences in 48 kindergarteners' and second graders' performance on a referential communication task in light of the Pascual-Leone Theory of Constructive Operations, a neo-Piagetian theory of cognitive development. Stimulus materials were black and white photographs of dogs,…

  9. A Czech Contribution to the Theme of Mauritius in Neo-Latin Drama

    Czech Academy of Sciences Publication Activity Database

    Förster, Josef

    -, č. 65 (2016), s. 367-381 ISSN 0774-2908 Institutional support: RVO:67985955 Keywords : Neo-Latin drama * Baroque literature * 18th century * The Czech lands Subject RIV: AJ - Letters, Mass-media, Audiovision

  10. Relative Binding Free Energy Calculations in Drug Discovery: Recent Advances and Practical Considerations.

    Science.gov (United States)

    Cournia, Zoe; Allen, Bryce; Sherman, Woody

    2017-12-26

    Accurate in silico prediction of protein-ligand binding affinities has been a primary objective of structure-based drug design for decades due to the putative value it would bring to the drug discovery process. However, computational methods have historically failed to deliver value in real-world drug discovery applications due to a variety of scientific, technical, and practical challenges. Recently, a family of approaches commonly referred to as relative binding free energy (RBFE) calculations, which rely on physics-based molecular simulations and statistical mechanics, have shown promise in reliably generating accurate predictions in the context of drug discovery projects. This advance arises from accumulating developments in the underlying scientific methods (decades of research on force fields and sampling algorithms) coupled with vast increases in computational resources (graphics processing units and cloud infrastructures). Mounting evidence from retrospective validation studies, blind challenge predictions, and prospective applications suggests that RBFE simulations can now predict the affinity differences for congeneric ligands with sufficient accuracy and throughput to deliver considerable value in hit-to-lead and lead optimization efforts. Here, we present an overview of current RBFE implementations, highlighting recent advances and remaining challenges, along with examples that emphasize practical considerations for obtaining reliable RBFE results. We focus specifically on relative binding free energies because the calculations are less computationally intensive than absolute binding free energy (ABFE) calculations and map directly onto the hit-to-lead and lead optimization processes, where the prediction of relative binding energies between a reference molecule and new ideas (virtual molecules) can be used to prioritize molecules for synthesis. We describe the critical aspects of running RBFE calculations, from both theoretical and applied perspectives

  11. A NeoPresocratic Manifesto

    Directory of Open Access Journals (Sweden)

    J. Baird Callicott

    2013-05-01

    Full Text Available Ancient Greek philosophy begins with natural philosophy (the Milesians, Heraclitus, Empedocles, Anaxagoras, followed after about a century by a focus on moral philosophy (Socrates and the sophists. The pattern is repeated in the Modern period: first natural philosophy re-emerged after the Dark and Middle Ages (Copernicus, Galileo, Descartes, Newton followed by a correlative revolution in moral philosophy (Hobbes, Hume, Kant. In particular, moral ontology (externally related individuals reflected the ontology of physics (externally related atoms. Individuals are, in effect, social atoms. Curiously, 20th-century philosophy has largely turned a blind eye and deaf ear to the vast philosophical implications of the second scientific revolution in 20th-century science, among them a correlative moral ontology of internal relations and social wholes. The environmental turn in the humanities, grounded in ecology and evolutionary biology, is a harbinger of the re-orientation of philosophy to the revolutionary ideas in the sciences and foreshadows an emerging NeoPresocratic revival in 21st-century philosophy.

  12. Investigation of neutrino properties in experiments at nuclear reactors: Present status and prospects

    International Nuclear Information System (INIS)

    Mikaelyan, L.A.

    2002-01-01

    The present status of experiments that are being performed at nuclear reactors in order to seek the neutrino masses, mixing, and magnetic moments, whose discovery would be a signal of the existence of physics beyond the Standard Model, is considered, along with their future prospects

  13. Caminhos do pensamento neo-schumpeteriano: para além das analogias biológicas

    Directory of Open Access Journals (Sweden)

    Rosana Icassatti Corazza

    2009-06-01

    Full Text Available This paper aims at contributing to the discussion of the theoretical construction of neo-schumpeterian approach of technical and economic change. Firstly, some fundamental arguments of this approach which are built in analogy to the evolutionist conception of Biological Sciences are presented. Secondly, we intended to distinguish, in recent literature, how neo-schumpeterian thinking evolves beyond such analogies, by integrating the concept of self-organization as the explaining element of the dynamic and evolving character of economic systems. Finally, some implications of such new perspective for the new-Schumpeterian research agenda are identified.

  14. History of gas fuels in France

    International Nuclear Information System (INIS)

    Anon.

    1996-01-01

    Summarizing the history of gas fuels in France consist essentially in the description of an economic and tax adventure with shortage constraints. The technology itself was developed long time ago and its principle do not raise any problem except for its optimization. The first LPG car was built in 1912 in the USA and fixed engines using town-gas as fuel were developed earlier. The French experience started during the second World War liquid fuels shortage and with the discovery of the Saint-Marcet gas field. The following history is directly related to the geopolitical fluctuations of energy supplies such as the independence of Algeria and the successive petroleum crashes. This short paper describes separately the evolution of natural gas for vehicles (NGV) and LPG fuels. The development of LPG fuels for public use vehicles started in 1979 but did not reached its expected impact due to the single-fuel constraint for vehicle design, applied until 1985, and to an unfavourable tax policy. Only public companies were capable to develop their own LPG vehicles fleet. The tendency of LPG development has recently changed as a consequence of the reinforcement of the environmental and economical policies initiated during the 70's. (J.S.)

  15. Gettin' a Little Crafty: Teachers Pay Teachers©, Pinterest© and Neo-Liberalism in New Materialist Feminist Research

    Science.gov (United States)

    Pittard, Elizabeth A.

    2017-01-01

    In this paper, I share data from a year-long study investigating the manifestations of neo-liberalism in the working lives of five women elementary school teachers in the United States. I discuss how gendered discourses of neo-liberalism construct what is understood as possible in the material-discursive production of the women's subjectivities…

  16. The manufacture of plutonium fuels for light water reactors

    International Nuclear Information System (INIS)

    Lebastard, G.

    1985-01-01

    This paper describes the agreement concluded between COGEMA and BELGONUCLEAIRE, reflected in the creation of the COMMOX group which has been made reponsible for promoting and marketing plutonium fuel rods for light water reactors. One then analyses the main aspects of manufacturing this type of fuel and the resources deployed. Finally one indicates the sales prospects scheduled to meet requirements (MELOX plant) [fr

  17. Computation fluid dynamic modelling of natural convection heat flow in unpumped molten salt fuel tubes

    International Nuclear Information System (INIS)

    Leefe, S.; Jackson-Laver, P.; Scott, I.R.

    2015-01-01

    Use of static molten salt nuclear fuel in simple tubes was discarded in 1949 without considering how convection could affect its utility. This poster describes CFD studies showing that such tubes are practical as fuel elements in essentially conventional fuel assemblies. They can achieve power densities above 250kW per liter of fuel salt (higher than PWR's) and do so without causing the tube wall to heat to dangerous levels. This discovery enables the achievement of the many benefits of molten salt fuel while utilizing the highly developed technology, regulatory, non proliferation and safety benefits of current fuel assembly technology. (author)

  18. MeV and GeV prospects for producing a large ion layer configuration for fusion power generation and breeding

    International Nuclear Information System (INIS)

    McNally, J.R. Jr.

    1983-01-01

    Injection of multi-MeV molecular hydrogen ions into a magnetic mirror or magnetic mirror well can lead to the production of an ion (or proton-E) Layer with prospects for fusion power generation. This involves: (1) slow (exponential or Lorentz) trapping of protons from dissociation and/or ionization of H 2 + ions; (2) electron cyclotron drive of the electronic temperature to reduce the electron stopping power; (3) production of an Ion-Layer, E-Core plasma configuration having prospects for cold fuel feed with in situ axial acceleration of say D 2 + ions into the negative E-Core; (4) ignited advanced fuel burns in the resulting high beta plasma with excess (free) neutrons available for energy multiplication of fissile fuel breeding; (5) development of a nuclear dynamo with fuel feed, plasma energy, and Ion-Layer current maintenance by fusion products; and (6) a natural divertor end loss of ashes with charge separation permitting a natural direct electrical conversion prospect

  19. Quantifying the potential impacts of fuel treatments on wildfire suppression costs

    Science.gov (United States)

    Matthew P. Thompson; Nicole M. Vaillant; Jessica R. Haas; Krista M. Gebert; Keith D. Stockmann

    2013-01-01

    Modeling the impacts and effects of hazardous fuel reduction treatments is a pressing issue within the wildfire management community. Prospective evaluation of fuel treatment effectiveness allows for comparison of alternative treatment strategies in terms of socioeconomic and ecological impacts and facilitates analysis of tradeoffs across land-management objectives....

  20. WWER reactor fuel performance, modelling and experimental support. Proceedings

    International Nuclear Information System (INIS)

    Stefanova, S.; Chantoin, P.; Kolev, I.

    1994-01-01

    This publication is a compilation of 36 papers presented at the International Seminar on WWER Reactor Fuel Performance, Modelling and Experimental Support, organised by the Institute for Nuclear Research and Nuclear Energy (BG), in cooperation with the International Atomic Energy Agency. The Seminar was attended by 76 participants from 16 countries, including representatives of all major Russian plants and institutions responsible for WWER reactor fuel manufacturing, design and research. The reports are grouped in four chapters: 1) WWER Fuel Performance and Economics: Status and Improvement Prospects: 2) WWER Fuel Behaviour Modelling and Experimental Support; 3) Licensing of WWER Fuel and Fuel Analysis Codes; 4) Spent Fuel of WWER Plants. The reports from the corresponding four panel discussion sessions are also included. All individual papers are recorded in INIS as separate items

  1. WWER reactor fuel performance, modelling and experimental support. Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    Stefanova, S; Chantoin, P; Kolev, I [eds.

    1994-12-31

    This publication is a compilation of 36 papers presented at the International Seminar on WWER Reactor Fuel Performance, Modelling and Experimental Support, organised by the Institute for Nuclear Research and Nuclear Energy (BG), in cooperation with the International Atomic Energy Agency. The Seminar was attended by 76 participants from 16 countries, including representatives of all major Russian plants and institutions responsible for WWER reactor fuel manufacturing, design and research. The reports are grouped in four chapters: (1) WWER Fuel Performance and Economics: Status and Improvement Prospects: (2) WWER Fuel Behaviour Modelling and Experimental Support; (3) Licensing of WWER Fuel and Fuel Analysis Codes; (4) Spent Fuel of WWER Plants. The reports from the corresponding four panel discussion sessions are also included. All individual papers are recorded in INIS as separate items.

  2. Expanding the framework of the holism/reductionism debate in neo-Darwinism: the case of Theodosius Dobzhansky and Bernhard Rensch.

    Science.gov (United States)

    Delisle, Richard G

    2008-01-01

    The holism/reductionism debate in evolutionary biology has often been analysed as involving two main phenomenological levels within neo-Darwinism: genetic and organismic. This analytical framework assumes that explanation in evolution is either found in the field of genetics or the field of organismic biology. It is argued here that this framework is far too restrictive to incorporate what at least some founding members of neo-Darwinism had in mind in their search for the ultimate cause of evolution. Dobzhansky's "super-holism" locates this drive in the highest possible entity imaginable--an ontologically unified evolutionary cosmos--while Rensch's ontological "super-reductionism," on the other hand, places it at the lowest possible entity of microphysics, that is, at the level of an energetic field of protopsychical nature. Not only it is suggested that a much-expanded framework is required for analysing the holism/reductionism debate in neo-Darwinism, but also that this new framework may have implications for the conceptualization of the neo-Darwinian movement itself.

  3. Design and fuel management of PWR cores to optimize the once-through fuel cycle

    International Nuclear Information System (INIS)

    Fujita, E.K.; Driscoll, M.J.; Lanning, D.D.

    1978-08-01

    The once-through fuel cycle has been analyzed to see if there are substantial prospects for improved uranium ore utilization in current light water reactors, with a specific focus on pressurized water reactors. The types of changes which have been examined are: (1) re-optimization of fuel pin diameter and lattice pitch, (2) axial power shaping by enrichment gradation in fresh fuel, (3) use of 6-batch cores with semi-annual refueling, (4) use of 6-batch cores with annual refueling, hence greater extended (approximately doubled) burnup, (5) use of radial reflector assemblies, (6) use of internally heterogeneous cores (simple seed/blanket configurations), (7) use of power/temperature coastdown at the end of life to extend burnup, (8) use of metal or diluted oxide fuel, (9) use of thorium, and (10) use of isotopically separated low sigma/sub a/ cladding material. State-of-the-art LWR computational methods, LEOPARD/PDQ-7/FLARE-G, were used to investigate these modifications

  4. Seed production for fuel oils

    International Nuclear Information System (INIS)

    Mosca, G.

    1992-01-01

    With the aim of assessing commercialization prospects for vegetable oils to be used as diesel fuel alternatives, this paper provides maps indicating regional production quantities for soybean, rape and sunflower seeds in Italy. It then tables and discusses the results of energy input-output analyses carried out for rape and soybean oil production

  5. Discovery and introduction of a (3,18)-connected net as an ideal blueprint for the design of metal-organic frameworks

    KAUST Repository

    Guillerm, Vincent; Weselinski, Lukasz Jan; Belmabkhout, Youssef; Cairns, Amy; D'Elia, Valerio; Wojtas, Łukasz; Adil, Karim; Eddaoudi, Mohamed

    2014-01-01

    -organic polyhedra act as supermolecular building blocks when they form gea-MOF-2. The discovery of a (3,18)-connected MOF followed by deliberate transposition of its topology to a predesigned second MOF with a different chemical system validates the prospective

  6. Novos encontros de anofelíneos em recipientes artificiais

    Directory of Open Access Journals (Sweden)

    Oswaldo Paulo Forattini

    1998-12-01

    Full Text Available Assinalam-se novos encontros de anofelíneos em recipientes artificiais. Um deles diz respeito a formas imaturas de Anopheles bellator em criadouros experimentais e outro é concernente ao achado de An. albitarsis l.s., em recipiente abandonado. Tecem-se considerações sobre a pressão seletiva representada pela produção, cada vez maior, de objetos descartáveis.

  7. Topology Discovery Using Cisco Discovery Protocol

    OpenAIRE

    Rodriguez, Sergio R.

    2009-01-01

    In this paper we address the problem of discovering network topology in proprietary networks. Namely, we investigate topology discovery in Cisco-based networks. Cisco devices run Cisco Discovery Protocol (CDP) which holds information about these devices. We first compare properties of topologies that can be obtained from networks deploying CDP versus Spanning Tree Protocol (STP) and Management Information Base (MIB) Forwarding Database (FDB). Then we describe a method of discovering topology ...

  8. Neo-Extractivism in Latin America – one side of a new phase of global capitalist dynamics

    OpenAIRE

    Ulrich Brand; Kristina Dietz; Miriam Lang

    2016-01-01

    The aim of this text is to make sense of the emerging political-institutional, territorial, and socio-ecological dynamics and contradictions of neo-extractivism in Latin America in the context of global capitalist development. In contrast to some existing literature, we argue that the term ‘neo-extractivism’ should not be restricted to countries with progressive governments but be applied to all Latin American societies that, since the 1970s and especially since the year 2000, depend predomin...

  9. Two decades of Neo-Marxist class analysis and health inequalities: A critical reconstruction

    Science.gov (United States)

    Muntaner, Carles; Ng, Edwin; Chung, Haejoo; Prins, Seth J

    2015-01-01

    Most population health researchers conceptualize social class as a set of attributes and material conditions of life of individuals. The empiricist tradition of ‘class as an individual attribute' equates class to an ‘observation', precluding the investigation of unobservable social mechanisms. Another consequence of this view of social class is that it cannot be conceptualized, measured, or intervened upon at the meso- or macro levels, being reduced to a personal attribute. Thus, population health disciplines marginalize rich traditions in Marxist theory whereby ‘class' is understood as a ‘hidden' social mechanism such as exploitation. Yet Neo-Marxist social class has been used over the last two decades in population health research as a way of understanding how health inequalities are produced. The Neo-Marxist approach views social class in terms of class relations that give persons control over productive assets and the labour power of others (property and managerial relations). We critically appraise the contribution of the Neo-Marxist approach during the last two decades and suggest realist amendments to understand class effects on the social determinants of health and health outcomes. We argue that when social class is viewed as a social causal mechanism it can inform social change to reduce health inequalities. PMID:26345311

  10. The prospect for fuel ion ratio measurements in ITER by collective Thomson scattering

    DEFF Research Database (Denmark)

    Stejner Pedersen, Morten; Korsholm, Søren Bang; Nielsen, Stefan Kragh

    2012-01-01

    We show that collective Thomson scattering (CTS) holds the potential to become a new diagnostic principle for measurements of the fuel ion ratio, nT/nD, in ITER. Fuel ion ratio measurements will be important for plasma control and machine protection in ITER. Measurements of ion cyclotron structures...... in CTS spectra have been suggested as the basis for a new fuel ion ratio diagnostic which would be well suited for reactor environments and capable of providing spatially resolved measurements in the plasma core. Such measurements were demonstrated in recent experiments in the TEXTOR tokamak. Here we...... conduct a sensitivity study to investigate the potential measurement accuracy of a CTS fuel ion ratio diagnostic on ITER. The study identifies regions of parameter space in which CTS can be expected to provide useful information on plasma composition, and we find that a CTS fuel ion ratio diagnostic could...

  11. Neo-liberali·sm and Changing Customary Lan-d Tenure Systems in ...

    African Journals Online (AJOL)

    reforms in Africa. Neo-liberal policies, demographic pressures, urbanization and ...... resulting from the emergence of diverse needs for land and the need for cash ..... Symposium At the.frontier of land issues: social embeddedness of rights.

  12. Multifactorial Optimization of Contrast-Enhanced Nanofocus Computed Tomography for Quantitative Analysis of Neo-Tissue Formation in Tissue Engineering Constructs.

    Directory of Open Access Journals (Sweden)

    Maarten Sonnaert

    Full Text Available To progress the fields of tissue engineering (TE and regenerative medicine, development of quantitative methods for non-invasive three dimensional characterization of engineered constructs (i.e. cells/tissue combined with scaffolds becomes essential. In this study, we have defined the most optimal staining conditions for contrast-enhanced nanofocus computed tomography for three dimensional visualization and quantitative analysis of in vitro engineered neo-tissue (i.e. extracellular matrix containing cells in perfusion bioreactor-developed Ti6Al4V constructs. A fractional factorial 'design of experiments' approach was used to elucidate the influence of the staining time and concentration of two contrast agents (Hexabrix and phosphotungstic acid and the neo-tissue volume on the image contrast and dataset quality. Additionally, the neo-tissue shrinkage that was induced by phosphotungstic acid staining was quantified to determine the operating window within which this contrast agent can be accurately applied. For Hexabrix the staining concentration was the main parameter influencing image contrast and dataset quality. Using phosphotungstic acid the staining concentration had a significant influence on the image contrast while both staining concentration and neo-tissue volume had an influence on the dataset quality. The use of high concentrations of phosphotungstic acid did however introduce significant shrinkage of the neo-tissue indicating that, despite sub-optimal image contrast, low concentrations of this staining agent should be used to enable quantitative analysis. To conclude, design of experiments allowed us to define the most optimal staining conditions for contrast-enhanced nanofocus computed tomography to be used as a routine screening tool of neo-tissue formation in Ti6Al4V constructs, transforming it into a robust three dimensional quality control methodology.

  13. The Value Of Enhanced Neo Surveys

    Science.gov (United States)

    Harris, Alan W.

    2012-10-01

    NEO surveys have now achieved, more or less, the “Spaceguard Goal” of cataloging 90% of NEAs larger than 1 km in diameter, and thereby have reduced the short-term hazard from cosmic impacts by about an order of magnitude, from an actuarial estimate of 1,000 deaths per year (actually about a billion every million years, with very little in between), to about 100 deaths per year, with a shift toward smaller but more frequent events accounting for the remaining risk. It is fair to ask, then, what is the value of a next-generation accelerated survey to “retire” much of the remaining risk. The curve of completion of survey versus size of NEA is remarkably similar for any survey, ground or space based, visible light or thermal IR, so it is possible to integrate risk over all sizes, with a time variable curve of completion to evaluate the actuarial value of speeding up survey completion. I will present my latest estimate of NEA population and completion of surveys. From those I will estimate the “value” of accelerated surveys such as Pan-STARRS, LSST, or space-based surveys, versus continuing with current surveys. My tentative conclusion is that we may have already reached the point in terms of cost-benefit where accelerated surveys are not cost-effective in terms of reducing impact risk. If not yet, we soon will. On the other hand, the surveys, which find and catalog main-belt and other classes of small bodies as well as NEOs, have provided a gold mine of good science. The scientific value of continued or accelerated surveys needs to be emphasized as the impact risk is increasingly “retired.”

  14. Cráneos de tzompantli bajo la Catedral Metropolitana de la Ciudad de México

    OpenAIRE

    Solari, Ana

    2008-01-01

    A partir de los trabajos de rescate arqueológico efectuados entre los años 1991 y 1996 por el Programa de Arqueología Urbana debajo de la Catedral y el Sagrario metropolitanos de la Ciudad de México, se han podido registrar y recuperar numerosos vestigios del antiguo Recinto Sagrado de México-Tenochtitlan. Se presentan aquí los resultados de las investigaciones realizadas a partir de un grupo de cráneos de tzompantli, es decir, cráneos con perforaciones en sus huesos parietales y temporales y...

  15. Topical papers on heavy water, fuel fabrication and reactors

    International Nuclear Information System (INIS)

    1978-01-01

    A total of four papers is presented. The first contribution of the Federal Republic of Germany reviews the market situation for reactors and the relations between reactor producers and buyers as reflected in sales agreements. The second West German contribution gives a world-wide survey of fuel element production as well as of fuel and fuel element demand up to the year 2000. The Canadian paper discusses the future prospects of heavy-water production, while the Ecuador contribution deals with small and medium-sized nuclear power plants

  16. Reconstruction of tau leptons and prospects for SUSY in ATLAS

    International Nuclear Information System (INIS)

    Zendler, Carolin

    2010-01-01

    Final states with tau leptons may play a special role among the broad variety of signatures for the production of supersymmetric particles at the LHC. The algorithms for tau reconstruction and identification are discussed, which are essential ingredients to reject the huge background from QCD processes. The status of analyses of SUSY tau lepton final states within the ATLAS experiment at the LHC are presented, which range from a study of semi-inclusive discovery prospects to more exclusive processes with two tau leptons from χ-tilde 2 0 decays and their implications for the determination of SUSY parameters. Also, the prospects for exploiting tau lepton polarization are discussed.

  17. The coherence of life: A new physiology challenging (neo)Darwinism

    Energy Technology Data Exchange (ETDEWEB)

    Jaeken, Laurent [Laboratory of Biochemistry, Department of Industrial Sciences and Technology, Karel de Grote-Hogeschool University College, Salesianenlaan 30, B-2660 Hoboken (Belgium)], E-mail: laurent.jaeken@Kdg.be

    2009-10-15

    Schroedinger argued that coherent behaviour is one of the most remarkable properties of life. Despite this, it is one of the most neglected properties, studied only by a few groups of rather independent scientists in the domains of physiology but also of fundamental physics. In contrast, classical cell physiology, built on membrane theory, does not take coherent behaviour into account. Recently several independent approaches to the problem of coherence have been unified yielding a new paradigm for cell physiology, which can be derived from a non-linear Schroedinger equation. The new paradigm replaces outdated membrane theory. Similarly (neo)Darwinism is not firmly grounded on fundamental physics. However, during the eighties (neo)Darwinism was taken up in a broader theory of evolution, based on the non-linear equations of fundamental physics. It is argued here that life's coherent behaviour and the new physiology built on these coherent properties is directly compatible with the modern view on evolution, since both are based on the same principles of non-linearity.

  18. Prospective economical study of the nuclear power file; Etude economique prospective de la filiere electrique nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    Charpin, J M [Commissariat General du Plan, 75 - Paris (France); Dessus, B [Ecodev-CNRS, 92 - Meudon (France); Pellat, R [CEA, 75 - Paris (France)

    2000-07-01

    On May 7, 1999 an economical study of the overall nuclear file, and in particular, of the back-end part of the fuel cycle and including the reprocessing, was requested by the French Prime Minister. This study includes the cost comparisons with the other means of power production and takes into consideration the environmental costs. The study is shared into five chapters dealing with: 1 - the legacy of the past: todays park of nuclear plants, economical and material status; 2 - the international evolution: the dynamics of nuclear policies worldwide (existing parks and R and D programs), the rise of environmental problems worldwide (CO{sub 2} and the climate convention, nuclear risks, attempts of including environment in the power costs), the choices made for the management of spent fuels in the main countries; 3 - the technological prospects for the power production and use: technologies for the mastery of power demand (residential, industrial and tertiary sectors, power transportation), technologies of power production (production from nuclear, fossil and renewable energies); 4 - prospective scenarios for France: two demand scenarios at the year 2050 vista (energy, electric power), power supply (supply structure with respect to scenarios, nuclear parks, power capacities), environmental aspects (CO{sub 2} emissions, plutonium and minor actinides production); 5 - the economical status of the different scenarios: data preparation, fossil fuel price scenarios, investment and operation costs of the different power production means (nuclear, fossil and renewable energies, natural gas and power distribution networks), comparison between fluxes and cumulated economic costs linked with the different scenarios (investments, exploitation, fuels, R and D, status for 2000 to 2050), time structure of expenditures with respect to the different scenarios (chronology, statuses, kWh costs, sensitivity with respect to the rate of discount, valorization of existing parks in 2050

  19. ‘”Wipe out lines of Division (Not Distinctions)’ : Bennie Keet, Neo-Calvinism and the Struggle against Apartheid’

    NARCIS (Netherlands)

    Harinck, George

    2017-01-01

    Race was not a dominant factor in neo-Calvinism. Rather, stress was laid on the universal character of Christianity, especially in the case of Herman Bavinck. While some of the South African PhD students at the Vrije Universiteit's defended apartheid with reference to neo-Calvinism, it was B.B. Keet

  20. The Emotional Dominant of Fear in Neo-Gothic Novel Via Opposition “Familiar - Alien” (on the Material of Neo-Gothic Novel I. Murdoch “The Unicorn”

    Directory of Open Access Journals (Sweden)

    Sergey Mihaylovich Pashkov

    2015-12-01

    Full Text Available The article dwells on the emotional dominant of fear in the text of neo-gothic fiction. This text type is popular with the readership and viewed as a manifestation of the socalled "culture of fear" (F. Furedi. The author analyzes the emotional dominant of fear in terms of the universal opposition "familiar - alien" that reflects the principles of dialogism, relevant for modern science. This opposition is localized in mind and determines man's emotional and aesthetic segmentation of the world in the process of its cognition. The universality of the opposition is seen in a treatment of its members: "familiar" – good; "alien" – bad. These members are usually associated with the category of space modeled in a text as a secondary modeling system (Y. M. Lotman. The author identifies the opposition by means of revealing opposite linguistic interdependences that are emotionally colored in a character's mind according to a writer's intention. It helps to distinguish correlative links between the structure of the emotional dominant of fear and the cyclicity of a plot of neo-gothic texts. "The familiar space" arouses positive emotions in a character but approaching, being in and moving off "the alien space" arouse predominant emotions (e.g. solitude, worry, foreboding, the dominating emotion proper (fear and postdominant emotions (e.g. joy, nostalgia, love respectively. The proposed approach to the analysis of the emotional dominant of fear, that is a subject-matter of the article, lets one arrange a complex emotive semantics of the neo-gothic text, make necessary emotional stresses that represent the emotional dynamics of a character (quasisubject and provide its systemic linguistic analysis.

  1. History, Status and Prospects on Development of Pyroprocess Technology

    International Nuclear Information System (INIS)

    Kim, Eung Ho; Lee, Han Soo; Park, Geunil; Seo, Chungseok; Ko, Wonil; Kim, Hodong; Choi, Jongwon

    2013-01-01

    The objective of this study is to evaluate prospects for a practical use of pyroprocess through analysis of current issues and status of pyroprocess technology development being performed at domestic and abroad. Following Fukushima accident, awareness about nuclear safety is further increasing and problems on safe management of used nuclear fuel has emerged as well. So, nuclear industrialized countries are developing recycling technology of used nuclear fuel, significantly reducing used fuel inventory that have cumulated. In this respects, there is a need to comprehensively summarize the technology developed at KAERI until now. In addition to, the current issues of pyroprocess for future R and D are suggested

  2. Discovery: Under the Microscope at Kennedy Space Center

    Science.gov (United States)

    Howard, Philip M.

    2013-01-01

    The National Aeronautics & Space Administration (NASA) is known for discovery, exploration, and advancement of knowledge. Since the days of Leeuwenhoek, microscopy has been at the forefront of discovery and knowledge. No truer is that statement than today at Kennedy Space Center (KSC), where microscopy plays a major role in contamination identification and is an integral part of failure analysis. Space exploration involves flight hardware undergoing rigorous "visually clean" inspections at every step of processing. The unknown contaminants that are discovered on these inspections can directly impact the mission by decreasing performance of sensors and scientific detectors on spacecraft and satellites, acting as micrometeorites, damaging critical sealing surfaces, and causing hazards to the crew of manned missions. This talk will discuss how microscopy has played a major role in all aspects of space port operations at KSC. Case studies will highlight years of analysis at the Materials Science Division including facility and payload contamination for the Navigation Signal Timing and Ranging Global Positioning Satellites (NA VST AR GPS) missions, quality control monitoring of monomethyl hydrazine fuel procurement for launch vehicle operations, Shuttle Solids Rocket Booster (SRB) foam processing failure analysis, and Space Shuttle Main Engine Cut-off (ECO) flight sensor anomaly analysis. What I hope to share with my fellow microscopists is some of the excitement of microscopy and how its discoveries has led to hardware processing, that has helped enable the successful launch of vehicles and space flight missions here at Kennedy Space Center.

  3. The potential of whey in driving microbial fuel cells: A dual prospect ...

    African Journals Online (AJOL)

    Renewable and green energy resources are paramount to environmental sustainability. Microbial fuel cells (MFCs) are potential candidates for these alternatives but there is need to search for cheaper fuels to drive the MFCs for realistic large scale applications. A high strength effluent such as whey, which poses a serious ...

  4. Neo-Liberalism and the Politics of Higher Education Policy in Indonesia

    Science.gov (United States)

    Rosser, Andrew

    2016-01-01

    This paper examines Indonesia's experience with neo-liberal higher education reform. It argues that this agenda has encountered strong resistance from the dominant predatory political, military, and bureaucratic elements who occupy the state apparatus, their corporate clients, and popular forces, leading to continuation of the centralist and…

  5. Pulp, noir or neo-noir? Aldo Nove's 'Cannibal Stories' in ...

    African Journals Online (AJOL)

    Libro di culto, Superwoobinda è soprattutto un'opera eclettica in cui si fondono i vari generi della cultura popolare – da pulp, trash e splatter al noir e neo-noir –, dandoavvio al meccanismo dell'auto – riflessività in letteratura. Infatti, dalla struttura formulare dei racconti che verte sull'assurdo e il grottesco, scaturisce il comico, ...

  6. The directed mutation controversy and neo-Darwinism.

    Science.gov (United States)

    Lenski, R E; Mittler, J E

    1993-01-08

    According to neo-Darwinian theory, random mutation produces genetic differences among organisms whereas natural selection tends to increase the frequency of advantageous alleles. However, several recent papers claim that certain mutations in bacteria and yeast occur at much higher rates specifically when the mutant phenotypes are advantageous. Various molecular models have been proposed that might explain these directed mutations, but the models have not been confirmed. Critics contend that studies purporting to demonstrate directed mutation lack certain controls and fail to account adequately for population dynamics. Further experiments that address these criticisms do not support the existence of directed mutations.

  7. Closing nuclear fuel cycle with fast reactors: problems and prospects

    Energy Technology Data Exchange (ETDEWEB)

    Shadrin, A.; Dvoeglazov, K.; Ivanov, V. [Bochvar Institute - VNIINM, Moscow (Russian Federation)

    2013-07-01

    The closed nuclear fuel cycle (CNFC) with fast reactors (FR) is the most promising way of nuclear energetics development because it prevents spent nuclear fuel (SNF) accumulation and minimizes radwaste volume due to minor actinides (MA) transmutation. CNFC with FR requires the elaboration of safety, environmentally acceptable and economically effective methods of treatment of SNF with high burn-up and low cooling time. The up-to-date industrially implemented SNF reprocessing technologies based on hydrometallurgical methods are not suitable for the reprocessing of SNF with high burn-up and low cooling time. The alternative dry methods (such as electrorefining in molten salts or fluoride technologies) applicable for such SNF reprocessing have not found implementation at industrial scale. So the cost of SNF reprocessing by means of dry technologies can hardly be estimated. Another problem of dry technologies is the recovery of fissionable materials pure enough for dense fuel fabrication. A combination of technical solutions performed with hydrometallurgical and dry technologies (pyro-technology) is proposed and it appears to be a promising way for the elaboration of economically, ecologically and socially accepted technology of FR SNF management. This paper deals with discussion of main principle of dry and aqueous operations combination that probably would provide safety and economic efficiency of the FR SNF reprocessing. (authors)

  8. Spent fuel management: current status and prospects of the IAEA programme

    International Nuclear Information System (INIS)

    1987-05-01

    This report, which is a result of the second IAEA Advisory Group Meeting, is intended to provide the reader with an overview of the status of Spent Fuel Management Programmes in a number of leading countries, with a description of the past IAEA activities in this field of Nuclear Fuel Cycle and with the Agency's plans for the next 2-3 years, based on the proposals of Member States. Separate abstracts were prepared for each of the 16 papers in this report

  9. Linfoma primario cutáneo difuso de células B grandes, tipo pierna (LPCDCBG-TP), localizado en cuero cabelludo

    OpenAIRE

    Felipe Fereira, Oristel I; Leonardo, Eugenio; Hernández Vázquez, Juan

    2010-01-01

    Los linfomas primarios cutáneos de células B se consideran actualmente como categoría distintiva de los linfomas primarios cutáneos y se reconocen subtipos característicos dentro de ellos. Se presenta un caso de linfoma primario cutáneo difuso de células B grandes, tipo pierna, con localización en el cuero cabelludo, donde se pudo disponer de estudios inmunohistoquímicos para su tipificación, que mostraron positividad para los marcadores CD20, bcl-2 y MUM-1, y negatividad para CD3 y bcl-6. Es...

  10. Behavior of spent nuclear fuel in water pool storage

    International Nuclear Information System (INIS)

    Johnson, A.B. Jr.

    1977-09-01

    Storage of irradiated nuclear fuel in water pools (basins) has been standard practice since nuclear reactors first began operation approximately 34 years ago. Pool storage is the starting point for all other fuel storage candidate processes and is a candidate for extended interim fuel storage until policy questions regarding reprocessing and ultimate disposal have been resolved. This report assesses the current performance of nuclear fuel in pool storage, the range of storage conditions, and the prospects for extending residence times. The assessment is based on visits to five U.S. and Canadian fuel storage sites, representing nine storage pools, and on discussions with operators of an additional 21 storage pools. Spent fuel storage experience from British pools at Winfrith and Windscale and from a German pool at Karlsruhe (WAK) also is summarized

  11. Home kitchen ventilation, cooking fuels, and lung cancer risk in a prospective cohort of never smoking women in Shanghai, China.

    Science.gov (United States)

    Kim, Christopher; Gao, Yu-Tang; Xiang, Yong-Bing; Barone-Adesi, Francesco; Zhang, Yawei; Hosgood, H Dean; Ma, Shuangge; Shu, Xiao-ou; Ji, Bu-Tian; Chow, Wong-Ho; Seow, Wei Jie; Bassig, Bryan; Cai, Qiuyin; Zheng, Wei; Rothman, Nathaniel; Lan, Qing

    2015-02-01

    Indoor air pollution (IAP) caused by cooking has been associated with lung cancer risk in retrospective case-control studies in developing and rural countries. We report the association of cooking conditions, fuel use, oil use, and risk of lung cancer in a developed urban population in a prospective cohort of women in Shanghai. A total of 71,320 never smoking women were followed from 1996 through 2009 and 429 incident lung cancer cases were identified. Questionnaires collected information on household living and cooking practices for the three most recent residences and utilization of cooking fuel and oil, and ventilation conditions. Cox proportional hazards regression estimated the association for kitchen ventilation conditions, cooking fuels, and use of cooking oils for the risk of lung cancer by hazard ratios (HR) with 95% confidence intervals (95% CI). Ever poor kitchen ventilation was associated with a 49% increase in lung cancer risk (HR: 1.49; 95% CI: 1.15-1.95) compared to never poor ventilation. Ever use of coal was not significantly associated. However, ever coal use with poor ventilation (HR: 1.69; 95% CI: 1.22-2.35) and 20 or more years of using coal with poor ventilation (HR: 2.03; 95% CI: 1.35-3.05) was significantly associated compared to no exposure to coal or poor ventilation. Cooking oil use was not significantly associated. These results demonstrate that IAP from poor ventilation of coal combustion increases the risk of lung cancer and is an important public health issue in cities across China where people may have lived in homes with inadequate kitchen ventilation. © 2014 UICC.

  12. The structure of Canada's uranium industry and its future market prospects

    International Nuclear Information System (INIS)

    1981-01-01

    Production of uranium in Canada began in the 1940s to supply the needs of US weapons development. After 1966 a growing demand for uranium for nuclear power production stimulated exploration, and since then the health of the Canadian uranium industry has been tied to the state of the nuclear power industry. Uranium exploration in Canada is carried out mainly by private enterprise, although the federal and two provincial governments compete through crown corporations. Seven companies produce ore, and six have processing plants. Expansion is underway at several existing operations, and some new projects are underway. The industry is strongly dependent on export markets; only about 15 percent of Canadian production is used in the country. There is one uranium refinery which produces UO 2 powder for CANDU reactor fuel and UF 6 for export. The uranium hexafluoride facility is being expanded. Federal government policy affects the uranium industry in the fields of regulation, ownership, safeguards, protection of the domestic industry, and international marketing. The short-term outlook for the industry is deteriorating, with declining uranium prices, but prospects seem considerably brighter in the longer term. Canada has about 12 percent of the world's uranium reserves, and is the second-largest producer. Discovery potential is believed to be excellent

  13. Effect of partial saturation of bonded neo magnet on the automotive accessory motor

    Directory of Open Access Journals (Sweden)

    Nimitkumar K. Sheth

    2017-05-01

    Full Text Available In this paper the effects of using a partially magnetized bonded neo (NdFeB magnet in an automotive accessory motor are presented. The potential reason for partial saturation of the bonded neo magnet is explained and a simple method to ensure saturation of the magnet is discussed. A magnetizing fixture design using the 2-D Finite element analysis (FEA is presented. The motor performance at various magnet saturation levels has been estimated using the 2-D FEA. Details of the thermal demagnetization test adopted by the automotive industry is also discussed and results of the motor performance for four saturation levels are detailed. These results indicate that the effect of demagnetization is more adverse in a motor with partially saturated magnets.

  14. Effect of partial saturation of bonded neo magnet on the automotive accessory motor

    Science.gov (United States)

    Sheth, Nimitkumar K.; Angara, Raghu C. S. Babu

    2017-05-01

    In this paper the effects of using a partially magnetized bonded neo (NdFeB) magnet in an automotive accessory motor are presented. The potential reason for partial saturation of the bonded neo magnet is explained and a simple method to ensure saturation of the magnet is discussed. A magnetizing fixture design using the 2-D Finite element analysis (FEA) is presented. The motor performance at various magnet saturation levels has been estimated using the 2-D FEA. Details of the thermal demagnetization test adopted by the automotive industry is also discussed and results of the motor performance for four saturation levels are detailed. These results indicate that the effect of demagnetization is more adverse in a motor with partially saturated magnets.

  15. Competition still fierce in the US fuel fabrication market

    International Nuclear Information System (INIS)

    Schwartz, M.H.

    1990-01-01

    The US market for nuclear fuel fabrication services is characterized by an annual production capacity significantly in excess of both current and anticipated demand. The trends toward longer operating cycle lengths and higher burnup fuel continue in the United States. This, together with the lack of any prospects for new light water reactors coming on line in the US during the next ten years, is expected to hold the annual demand for fuel fabrication services from US LWRs at around 2000t of uranium into the next century. (author)

  16. IMG-ABC: An Atlas of Biosynthetic Gene Clusters to Fuel the Discovery of Novel Secondary Metabolites

    Energy Technology Data Exchange (ETDEWEB)

    Chen, I-Min; Chu, Ken; Ratner, Anna; Palaniappan, Krishna; Huang, Jinghua; Reddy, T. B.K.; Cimermancic, Peter; Fischbach, Michael; Ivanova, Natalia; Markowitz, Victor; Kyrpides, Nikos; Pati, Amrita

    2014-10-28

    In the discovery of secondary metabolites (SMs), large-scale analysis of sequence data is a promising exploration path that remains largely underutilized due to the lack of relevant computational resources. We present IMG-ABC (https://img.jgi.doe.gov/abc/) -- An Atlas of Biosynthetic gene Clusters within the Integrated Microbial Genomes (IMG) system1. IMG-ABC is a rich repository of both validated and predicted biosynthetic clusters (BCs) in cultured isolates, single-cells and metagenomes linked with the SM chemicals they produce and enhanced with focused analysis tools within IMG. The underlying scalable framework enables traversal of phylogenetic dark matter and chemical structure space -- serving as a doorway to a new era in the discovery of novel molecules.

  17. Neo-glans reconstruction for penile cancer: Description of the primary technique using autologous testicular tunica vaginalis graft

    Directory of Open Access Journals (Sweden)

    Peter Weibl

    2018-06-01

    Neo-glans reconstruction with TV coverage may be another promising alternative, which certainly requires further evaluation. We believe that the donor-site associated morbidity is minimal when compared to other harvesting sites. However, this is just an assumption, because direct comparison data on grafting techniques and neo-glans reconstruction are not available. Nevertheless, we think that for re-do procedures a standardised approach using a STSG technique should be the treatment method of choice.

  18. Prospect of spent fuel reprocessing and back-end cycling in China in 1990's

    International Nuclear Information System (INIS)

    Ke Youzhi; Wang Rengtao

    1987-01-01

    According to the CHinese Program of nuclear energy in 1990's, the amount of spent fuel by the year 2000 is estimated in this paper. Reprocessing is considered as an important link in the back-end fuel cycle. A pilot plant is scheduled for hot start up in 1996. The main goal of the study is LWR spent fuel reprocessing. We will use the experience gained from reprocessing of production reactor fuel and last research results. The advanced foreign technigue and experience will be introduced. The study emphasizes on the test of technology, equipments, instrumentation and automation, development of remote maintenance and decontamination. China will start to demonstrate the way for fuel cycle. (author)

  19. Investigation of Lubrication Properties of Petroleum Fuel and Biohydrocarbon Blends

    Directory of Open Access Journals (Sweden)

    Gawron Bartosz

    2016-07-01

    Full Text Available The paper covers issues regarding lubricity of petroleum fuels used in piston and turbine engines, containing hydrocarbon biocomponents. Basing on available literature it can be said that the most prospective fuel components are biohydrocarbons. The paper describes effect of biohydrocarbons included in aviation fuel and diesel fuel on lubricity of such blends. The analysis covers two processes for obtaining biohydrocarbons, the HVO and the Fischer-Tropsch process. Due to problems with actual products acquiring, biohydrocarbons models representing chemically the actual ones from specific process. Lubricity testing was carried out according to standard test methods.

  20. Teacher Change in an Era of Neo-Liberal Policies: A Neoinstitutional Analysis of Teachers' Perceptions of Their Professional Change

    Science.gov (United States)

    Ramberg, Magnus Rye

    2014-01-01

    The aim of this article is to explore how neo-institutional theory may be applied as an analytical framework to investigate the relationships between teachers' perceptions on their professional change on the one hand, and the numerous change efforts embedded in recent neo-liberal educational policies in Norway on the other. Based on biographical…

  1. 14 CFR 406.143 - Discovery.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Discovery. 406.143 Section 406.143... Transportation Adjudications § 406.143 Discovery. (a) Initiation of discovery. Any party may initiate discovery... after a complaint has been filed. (b) Methods of discovery. The following methods of discovery are...

  2. Initial results of uranium prospecting in Baluchistan, Iran

    International Nuclear Information System (INIS)

    Hemmer, C.

    1980-01-01

    Uranium prospecting in Baluchistan, SE-Iran, led to the discovery of uranium occurrences at the northern rim of the undrained Jaz Murian Depression. All known uranium occurrences are epigenetic local enrichments of no economic significance which originate from mobilization of uranium from Tertiary acidic magmatic rocks. The great extent of both the uranium source and the host areas indicate significant uranium mobilization and a possible economic potential for the area as a uranium province in the future. (orig.) [de

  3. The future of Asian feminisms: confronting fundamentalisms, conflicts and neo-liberalism

    NARCIS (Netherlands)

    Katjasungkana, N.; Wieringa, S.E.

    2012-01-01

    This book on the future of Asian feminisms, confronting fundamentalisms, conflicts, and neo-liberalism is a critical contribution to the rising voices of Asian women’s studies scholars and activists. It is based on the ongoing research and advocacy work of the Kartini Asia Network, founded in 2003

  4. Alienation in Mathematics Education: A Problem Considered from Neo-Vygotskian Approaches

    Science.gov (United States)

    Radford, Luis; Roth, Wolff-Michael

    2017-01-01

    In a recent article published in this journal, Williams ("Educational Studies in Mathematics, 92," 59-72, 2016) offers a critique of neo-Vygotskian perspectives exemplified in recent work on the "funds of knowledge" and on "cultural-historical activity theoretic" perspectives. The critique has great value in that it…

  5. Current status and future prospects for enabling chemistry technology in the drug discovery process [version 1; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Stevan W. Djuric

    2016-09-01

    Full Text Available This review covers recent advances in the implementation of enabling chemistry technologies into the drug discovery process. Areas covered include parallel synthesis chemistry, high-throughput experimentation, automated synthesis and purification methods, flow chemistry methodology including photochemistry, electrochemistry, and the handling of “dangerous” reagents. Also featured are advances in the “computer-assisted drug design” area and the expanding application of novel mass spectrometry-based techniques to a wide range of drug discovery activities.

  6. Dynamic competition and enterprising discovery: Kirzner’s market process theory

    Directory of Open Access Journals (Sweden)

    Ahmet İhsan KAYA

    2011-12-01

    Full Text Available Market process theory is designed by the followers of Austrian School tradition as an alternative to neo-classic price theory in order to explain perceptible markets. Contrary to neo-classic economy which focuses on the concept of equilibrium, market process theory seeks to explore unequilibrium and direction to equilibrium. While doing so, the role of enterprenuer in dealing with limited information which is not taken into consideration in the price theory of neo-classic economy, uncertainty because of time and uncertainty which occurs in market underpins Israel Kirzner's analyses. In the study, Kirzner's competition and enterpreneurship theory is discussed with the contributions of Mises and Hayek. The study constitutes an introduction to market process theory of Kirzner.

  7. Selection of Fuel System for Modern Heavy Duty Diesel Engines

    Directory of Open Access Journals (Sweden)

    G. M. Kukharonok

    2004-01-01

    Full Text Available Fuel systems of diesel engines have been analyzed. The paper shows components of the systems, peculiarities of their manufacturing process. Difference in efficiency of the systems, their application and market prospects are considered in the paper. While solving problems to design a power installation the essence of fuel system selection is given on the basis of an internal combustion engine.

  8. French experience and prospects in the reprocessing of fast breeder reactor fuels

    International Nuclear Information System (INIS)

    Megy, J.

    1983-06-01

    Experience acquired in France in the field of reprocessing spent fuels from fast breeder reactors is recalled. Emphasis is put on characteristics and quantities of spent fuels reprocessed in La Hague and Marcoule facilities. Then reprocessing developments with the realisation of the new pilot plant TOR at Marcoule, new equipments and study of industrial reprocessing units are reviewed [fr

  9. Lung function and incidence of chronic obstructive pulmonary disease after improved cooking fuels and kitchen ventilation: a 9-year prospective cohort study.

    Directory of Open Access Journals (Sweden)

    Yumin Zhou

    2014-03-01

    Full Text Available BACKGROUND: Biomass smoke is associated with the risk of chronic obstructive pulmonary disease (COPD, but few studies have elaborated approaches to reduce the risk of COPD from biomass burning. The purpose of this study was to determine whether improved cooking fuels and ventilation have effects on pulmonary function and the incidence of COPD. METHODS AND FINDINGS: A 9-y prospective cohort study was conducted among 996 eligible participants aged at least 40 y from November 1, 2002, through November 30, 2011, in 12 villages in southern China. Interventions were implemented starting in 2002 to improve kitchen ventilation (by providing support and instruction for improving biomass stoves or installing exhaust fans and to promote the use of clean fuels (i.e., biogas instead of biomass for cooking (by providing support and instruction for installing household biogas digesters; questionnaire interviews and spirometry tests were performed in 2005, 2008, and 2011. That the interventions improved air quality was confirmed via measurements of indoor air pollutants (i.e., SO₂, CO, CO₂, NO₂, and particulate matter with an aerodynamic diameter of 10 µm or less in a randomly selected subset of the participants' homes. Annual declines in lung function and COPD incidence were compared between those who took up one, both, or neither of the interventions. Use of clean fuels and improved ventilation were associated with a reduced decline in forced expiratory volume in 1 s (FEV₁: decline in FEV₁ was reduced by 12 ml/y (95% CI, 4 to 20 ml/y and 13 ml/y (95% CI, 4 to 23 ml/y in those who used clean fuels and improved ventilation, respectively, compared to those who took up neither intervention, after adjustment for confounders. The combined improvements of use of clean fuels and improved ventilation had the greatest favorable effects on the decline in FEV₁, with a slowing of 16 ml/y (95% CI, 9 to 23 ml/y. The longer the duration of improved fuel use and

  10. Digital expression profiling identifies RUNX2, CDC5L, MDM2, RECQL4, and CDK4 as potential predictive biomarkers for neo-adjuvant chemotherapy response in paediatric osteosarcoma.

    Directory of Open Access Journals (Sweden)

    Jeffrey W Martin

    Full Text Available Osteosarcoma is the most common malignancy of bone, and occurs most frequently in children and adolescents. Currently, the most reliable technique for determining a patients' prognosis is measurement of histopathologic tumor necrosis following pre-operative neo-adjuvant chemotherapy. Unfavourable prognosis is indicated by less than 90% estimated necrosis of the tumor. Neither genetic testing nor molecular biomarkers for diagnosis and prognosis have been described for osteosarcomas. We used the novel nanoString mRNA digital expression analysis system to analyse gene expression in 32 patients with sporadic paediatric osteosarcoma. This system used specific molecular barcodes to quantify expression of a set of 17 genes associated with osteosarcoma tumorigenesis. Five genes, from this panel, which encoded the bone differentiation regulator RUNX2, the cell cycle regulator CDC5L, the TP53 transcriptional inactivator MDM2, the DNA helicase RECQL4, and the cyclin-dependent kinase gene CDK4, were differentially expressed in tumors that responded poorly to neo-adjuvant chemotherapy. Analysis of the signalling relationships of these genes, as well as other expression markers of osteosarcoma, indicated that gene networks linked to RB1, TP53, PI3K, PTEN/Akt, myc and RECQL4 are associated with osteosarcoma. The discovery of these networks provides a basis for further experimental studies of role of the five genes (RUNX2, CDC5L, MDM2, RECQL4, and CDK4 in differential response to chemotherapy.

  11. Seismic stability of the survey areas of potential sites for the deep geological repository of the spent nuclear fuel

    Science.gov (United States)

    Kaláb, Zdeněk; Šílený, Jan; Lednická, Markéta

    2017-07-01

    This paper deals with the seismic stability of the survey areas of potential sites for the deep geological repository of the spent nuclear fuel in the Czech Republic. The basic source of data for historical earthquakes up to 1990 was the seismic website [1-]. The most intense earthquake described occurred on September 15, 1590 in the Niederroesterreich region (Austria) in the historical period; its reported intensity is Io = 8-9. The source of the contemporary seismic data for the period since 1991 to the end of 2014 was the website [11]. It may be stated based on the databases and literature review that in the period from 1900, no earthquake exceeding magnitude 5.1 originated in the territory of the Czech Republic. In order to evaluate seismicity and to assess the impact of seismic effects at depths of hypothetical deep geological repository for the next time period, the neo-deterministic method was selected as an extension of the probabilistic method. Each one out of the seven survey areas were assessed by the neo-deterministic evaluation of the seismic wave-field excited by selected individual events and determining the maximum loading. Results of seismological databases studies and neo-deterministic analysis of Čihadlo locality are presented.

  12. Geochemical prospecting for uranium and thorium deposits

    International Nuclear Information System (INIS)

    Boyle, R.W.

    1980-01-01

    A brief review of analytical geochemical prospecting methods for uranium and thorium is given excluding radiometric techniques, except those utilized in the determination of radon. The indicator (pathfinder) elements useful in geochemical surveys are listed for each of the types of known uranium and thorium deposits; this is followed by sections on analytical geochemical surveys based on rocks (lithochemical surveys), unconsolidated materials (pedochemical surveys), natural waters and sediments (hydrochemical surveys), biological materials (biogeochemical surveys) and gases (atmochemical surveys). All of the analytical geochemical methods are applicable in prospecting for thorium and uranium, particularly where radiometric methods fail due to attenuation by overburden, water, deep leaching and so on. Efficiency in the discovery of uranium and/or thorium orebodies is promoted by an integrated methods approach employing geological pattern recognition in the localization of deposits, analytical geochemical surveys, and radiometric surveys. (author)

  13. CRITICALITY SAFETY CONTROL OF LEGACY FUEL FOUND AT 105-K WEST FUEL STORAGE BASIN

    International Nuclear Information System (INIS)

    JENSEN, M.A.

    2005-01-01

    In August 2004, two sealed canisters containing spent nuclear fuel were opened for processing at the Hanford Site's K West fuel storage basin. The fuel was to be processed through cleaning and sorting stations, repackaged into special baskets, placed into a cask, and removed from the basin for further processing and eventual dry storage. The canisters were expected to contain fuel from the old Hanford C Reactor, a graphite-moderated reactor fueled by very low-enriched uranium metal. The expected fuel type was an aluminum-clad slug about eight inches in length and with a weight of about eight pounds. Instead of the expected fuel, the two canisters contained several pieces of thin tubes, some with wire wraps. The material was placed into unsealed canisters for storage and to await further evaluation. Videotapes and still photographs of the items were examined in consultation with available retired Hanford employees. It was determined that the items had a fair probability of being cut-up pieces of fuel rods from the retired Hanford Plutonium Recycle Test Reactor (PRTR). Because the items had been safely handled several times, it was apparent that a criticality safety hazard did not exist when handling the material by itself, but it was necessary to determine if a hazard existed when combining the material with other known types of spent nuclear fuel. Because the PRTR operated more than 40 years ago, investigators had to rely on a combination of researching archived documents, and utilizing common-sense estimates coupled with bounding assumptions, to determine that the fuel items could be handled safely with other spent nuclear fuel in the storage basin. As older DOE facilities across the nation are shut down and cleaned out, the potential for more discoveries of this nature is increasing. As in this case, it is likely that only incomplete records will exist and that it will be increasingly difficult to immediately characterize the nature of the suspect fissionable

  14. Higgs Discovery

    DEFF Research Database (Denmark)

    Sannino, Francesco

    2013-01-01

    has been challenged by the discovery of a not-so-heavy Higgs-like state. I will therefore review the recent discovery \\cite{Foadi:2012bb} that the standard model top-induced radiative corrections naturally reduce the intrinsic non-perturbative mass of the composite Higgs state towards the desired...... via first principle lattice simulations with encouraging results. The new findings show that the recent naive claims made about new strong dynamics at the electroweak scale being disfavoured by the discovery of a not-so-heavy composite Higgs are unwarranted. I will then introduce the more speculative......I discuss the impact of the discovery of a Higgs-like state on composite dynamics starting by critically examining the reasons in favour of either an elementary or composite nature of this state. Accepting the standard model interpretation I re-address the standard model vacuum stability within...

  15. Two Marine Cyanobacterial Aplysiatoxin Polyketides, Neo-debromoaplysiatoxin A and B, with K+ Channel Inhibition Activity.

    Science.gov (United States)

    Han, Bing-Nan; Liang, Ting-Ting; Keen, Lawrence Jordan; Fan, Ting-Ting; Zhang, Xiao-Dan; Xu, Lin; Zhao, Qi; Wang, Shu-Ping; Lin, Hou-Wen

    2018-02-02

    The isolation and structure elucidation of two cyanobacterial debromoaplysiatoxin (DAT) analogues, neo-debromoaplysiatoxin A (1) and neo-debromoaplysiatoxin B (2), were reported and found to possess 6/10/6 and 6/6/6 fused-ring systems, respectively, which are rarely seen among aplysiatoxins. Both compounds exhibited potent blocking activity against Kv1.5 with IC 50 values of 6.94 ± 0.26 and 0.30 ± 0.05 μM, respectively. These findings suggest the potential of aplysiatoxin analogues in modulating ionic channels and also provide links between the DAT target, protein kinase C, and cell regulation.

  16. The legacy of fossil fuels.

    Science.gov (United States)

    Armaroli, Nicola; Balzani, Vincenzo

    2011-03-01

    Currently, over 80% of the energy used by mankind comes from fossil fuels. Harnessing coal, oil and gas, the energy resources contained in the store of our spaceship, Earth, has prompted a dramatic expansion in energy use and a substantial improvement in the quality of life of billions of individuals in some regions of the world. Powering our civilization with fossil fuels has been very convenient, but now we know that it entails severe consequences. We treat fossil fuels as a resource that anyone anywhere can extract and use in any fashion, and Earth's atmosphere, soil and oceans as a dump for their waste products, including more than 30 Gt/y of carbon dioxide. At present, environmental legacy rather than consistence of exploitable reserves, is the most dramatic problem posed by the relentless increase of fossil fuel global demand. Harmful effects on the environment and human health, usually not incorporated into the pricing of fossil fuels, include immediate and short-term impacts related to their discovery, extraction, transportation, distribution, and burning as well as climate change that are spread over time to future generations or over space to the entire planet. In this essay, several aspects of the fossil fuel legacy are discussed, such as alteration of the carbon cycle, carbon dioxide rise and its measurement, greenhouse effect, anthropogenic climate change, air pollution and human health, geoengineering proposals, land and water degradation, economic problems, indirect effects on the society, and the urgent need of regulatory efforts and related actions to promote a gradual transition out of the fossil fuel era. While manufacturing sustainable solar fuels appears to be a longer-time perspective, alternatives energy sources already exist that have the potential to replace fossil fuels as feedstocks for electricity production. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. The legacy of fossil fuels

    Energy Technology Data Exchange (ETDEWEB)

    Armaroli, N.; Balzani, V. [CNR, Bologna (Italy)

    2011-03-01

    Currently, over 80% of the energy used by mankind comes from fossil fuels. Harnessing coal, oil and gas, the energy resources contained in the store of our spaceship, Earth, has prompted a dramatic expansion in energy use and a substantial improvement in the quality of life of billions of individuals in some regions of the world. Powering our civilization with fossil fuels has been very convenient, but now we know that it entails severe consequences. We treat fossil fuels as a resource that anyone anywhere can extract and use in any fashion, and Earth's atmosphere, soil and oceans as a dump for their waste products, including more than 30 Gt/y of carbon dioxide. At present, environmental legacy rather than consistence of exploitable reserves, is the most dramatic problem posed by the relentless increase of fossil fuel global demand. Harmful effects on the environment and human health, usually not incorporated into the pricing of fossil fuels, include immediate and short-term impacts related to their discovery, extraction, transportation, distribution, and burning as well as climate change that are spread over time to future generations or over space to the entire planet. In this essay, several aspects of the fossil fuel legacy are discussed, such as alteration of the carbon cycle, carbon dioxide rise and its measurement, greenhouse effect, anthropogenic climate change, air pollution and human health, geoengineering proposals, land and water degradation, economic problems, indirect effects on the society, and the urgent need of regulatory efforts and related actions to promote a gradual transition out of the fossil fuel era. While manufacturing sustainable solar fuels appears to be a longer-time perspective, alternatives energy sources already exist that have the potential to replace fossil fuels as feedstocks for electricity production.

  18. Off-pump transapical implantation of artificial neo-chordae to correct mitral regurgitation: the TACT Trial (Transapical Artificial Chordae Tendinae) proof of concept.

    Science.gov (United States)

    Seeburger, Joerg; Rinaldi, Mauro; Nielsen, Sten Lyager; Salizzoni, Stefano; Lange, Ruediger; Schoenburg, Markus; Alfieri, Ottavio; Borger, Michael Andrew; Mohr, Friedrich Wilhelm; Aidietis, Audrius

    2014-03-11

    The goal of this study was to evaluate the safety and performance of the NeoChord DS1000 system (NeoChord, Inc., Minneapolis, Minnesota). There is an increasing interest in transcatheter mitral valve (MV) treatment. The NeoChord DS 1000 system enables off-pump beating heart transapical MV repair with implantation of artificial neo-chordae. Patients with severe mitral regurgitation (MR) due to isolated posterior prolapse were included in this TACT (Transapical Artificial Chordae Tendinae) trial. All patients were scheduled for off-pump transapical implantation of neo-chordae. Thirty patients at 7 centers were enrolled. Major adverse events included 1 death due to post-cardiotomy syndrome and concomitant sepsis and 1 minor stroke with the patient fully recovered at the 30-day follow-up visit. Additional patients experienced procedural major adverse events related to a reoperation or conversion to standard of care. Acute procedural success (placement of at least 1 neo-chord and reduction of MR from 3+ or 4+ to ≤2+) was achieved in 26 patients (86.7%). In 4 patients neo-chordae were not placed for technical and/or patient-specific reasons. These patients underwent intraoperative (3 patients) or post-operative (1 patient) standard MV repair. At 30 days, 17 patients maintained an MR grade ≤2+. Four patients who developed recurrent MR were successfully treated with open MV repair during 30-day follow-up. Results improved with experience: durable reduction in MR to ≤2+ at 30 days was achieved in 5 (33.3%) of the first 15 patients and 12 (85.7%) of the last 14 patients. Off-pump transapical implantation of artificial chordae to correct MR is technically safe and feasible; however, it yields further potential for improvement of efficacy and durability. (Safety and Performance Study of the NeoChord Device [TACT]; NCT01777815). Copyright © 2014 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

  19. Bio-diesel fuels production: Feasibility studies

    International Nuclear Information System (INIS)

    Tabasso, L.

    1993-01-01

    This paper reviews the efforts being made by Italy's national government and private industry to develop diesel engine fuels derived from vegetable oils, in particular, sunflower seed oil. These fuels are being promoted in Italy from the environmental protection stand-point in that they don't contain any sulfur, the main cause of acid rain, and from the agricultural stand-point in that they provide Italian farmers, whose food crop production capacity is limited due to European Communities agreements, with the opportunity to use their set-aside land for the production of energy crops. This paper provides brief notes on the key performance characteristics of bio-diesel fuels, whose application doesn't require any modifications to diesel engines, apart from minor adjustments to the air/fuel mix regulating system, and assesses commercialization prospects. Brief mention is made of the problems being encountered by the Government in the establishing fair bio-fuel production tax rebates which are compatible with the marketing practices of the petroleum industry. One of the strategies being considered is to use the bio-fuels as additives to be mixed with conventional fuel oils so as to derive a fuel which meets the new European air pollution standards

  20. Blood group genotyping Genotipagem de grupos sangüíneos

    Directory of Open Access Journals (Sweden)

    Lilian Castilho

    2004-01-01

    Full Text Available Accurate phenotyping of red blood cells (RBCs can be difficult in transfusion-dependent patients such as those with thalassemia and sickle cells anemia because of the presence of previously transfused RBCs in the patient's circulation. Recently, the molecular basis associated with the expression of many blood group antigens was established. This allowed the development of a plethora of polymerase chain reaction-based tests for identification of the blood group antigens by testing DNA. The determination of blood group polymorphism at the genomic level facilitates the resolution of clinical problems that cannot be addressed by hemagglutination. They are useful to (a determine antigen types for which currently available antibodies are weakly reactive; (b type patients who have been recently transfused; (c identify fetuses at risk for hemolytic disease of the newborn; and (d to increase the reliability of repositories of antigen negative RBCs for transfusion. It is important to note that PCR based assays are prone to different types of errors that those observed with hemagglutination assays. For instance, contamination with amplified products may lead to false positive test results. In addition, the identification of a particular genotype does not necessarily mean that the antigen will be expressed on the RBC membrane.Os antígenos eritrocitários são herdados geneticamente e definidos por seqüências de aminoácidos específicos constituindo uma proteína ou por carboidratos ligados a estas proteínas ou à lipídios. A diversidade dos antígenos de grupos sangüíneos, como para qualquer outro traço biológico, encontra-se ao nível do gene. Existem atualmente mais de 250 antígenos eritrocitários que se encontram distribuídos em 29 sistemas de grupos sangüíneos, de acordo com a Nomenclatura da Sociedade Internacional de Transfusão Sangüínea (ISBT. Os genes que codificam 28 dos 29 sistemas de grupos sangüíneos já foram clonados e seq

  1. Discovery of the Sierra Pintada uranium district, Mendoza Province, Argentina

    International Nuclear Information System (INIS)

    Rodrigo, F.; Belluco, A.E.

    1981-01-01

    Since 1956, uranium-bearing minerals have been known to exist in Sierra Pintada, Mendoza Province, Argentina. Based on paragenetic considerations, a first radiometric prospection was carried out, leading to the discovery of two groups of anomalies (Puesto Agua del Toro and Cuesta de los Terneros), such as vein-type deposits, with uraninite and 'yellow minerals' and one sandstone-type deposit (Puesto La Josefa), related to sediments with carbon trash. Some recent geological research and surveys in the area, and a reduced drilling programme carried out on selected anomalies, led to reinterpretation of the potential of the area. Furthermore, and as a result of an airborne radiometric prospection performed in mid-1968, numerous anomalies have been discovered. The main constellation of anomalies, along the flanks of the El Tigre Brachyanticline, occurs in sandstones of Permian age. Explored by 80 000 m of drilling, they have shown the existence of several peneconcordant lens-shaped ore bodies of economic size, with uranophane on the surface and prevailing uraninite and some brannerite, coffinite and davidite below the water table. Reserves exceed 20 000 tonnes of U 3 O 8 . A new regional programme with a 4-km drill-grid initiated in 1978 led to the discovery of new ore bodies which are at present being evaluated. The alternatives and discontinuities during the development of the district, the prospecting and exploration techniques employed, and the results achieved in the different stages of the operation are discussed in detail. This case history attempts to illustrate the developing philosophy which was successfully applied in Sierra Pintada, with emphasis on the following points: (a) the need for adequate geological knowledge of the area; (b) the advantage of a massive survey (in this case, air survey); (c) the necessity for exploration (drilling) in order to define the anomalies and make their evaluation possible; and (d) the convenience of extending exploration

  2. Quantifying the potential impacts of fuel treatments on wildfire suppression costs volume

    Science.gov (United States)

    Matthew P. Thompson; Nicole M. Vaillant; Jessica R. Haas; Krista M. Gebert; Keith D. Stockmann

    2013-01-01

    Modeling the impacts and effects of hazardous fuel reduction treatments is a pressing issue within the wildfire management community. Prospective evaluation of fuel treatments allows for comparison of alternative treatment strategies in terms of socioeconomic and ecological impacts and facilitates analysis of tradeoffs across land management objectives (Stockmann et al...

  3. Primeras experiencias con drenaje biliar percutáneo de urgencia en la colangitis aguda

    Directory of Open Access Journals (Sweden)

    José Luis González González

    Full Text Available Introducción: la obstrucción biliar es motivo frecuente de morbilidad en los pacientes con metástasis hepáticas, adenopatías periportales y cáncer hepatobiliopancreático. La colangitis aguda es la complicación más temida, debido a su mortalidad. En este trabajo se presentan los primeros abordajes percutáneos realizados por cirujanos del Hospital Clínicoquirúrgico "Hermanos Ameijeiras" como herramienta para el tratamiento urgente de esta entidad. Objetivo: caracterizar el drenaje percutáneo transparietohepático de urgencia en pacientes con colangitis aguda e ictericia obstructiva. Métodos: se realizó un estudio descriptivo, prospectivo y aplicado con 30 pacientes atendidos de esta forma en dicha institución entre enero de 2008 y diciembre de 2010. Resultados: el diagnóstico etiológico preponderante fue el de tumor maligno de la cabeza del páncreas. La localización baja de la lesión duplicó a la localización alta. La mejoría clínica de la ictericia se evidenció en la mayoría de los pacientes después de una semana tras el procedimiento: el drenaje percutáneo constituyó el método definitivo en el 73,3 % de los pacientes. Las edades medias para los distintos diagnósticos etiológicos exhibieron diferencias estadísticamente significativas. No hubo complicaciones ni mortalidad relacionadas con el procedimiento. Conclusiones: el drenaje biliar percutáneo guiado por ultrasonido es una herramienta útil y segura para el tratamiento de urgencia de la colangitis aguda. Es un método que pueden realizar los cirujanos generales con entrenamiento adecuado y específico, y tiene asociadas pocas complicaciones.

  4. Dataciones absolutas de los cráneos del yacimiento prehistórico de Urtiaga.

    Directory of Open Access Journals (Sweden)

    Jesús Altuna

    1989-01-01

    Full Text Available Los restos humanos recuperados en 1935 y 1936 por Aranzadi y Barandiarán en el yacimiento de Urtiaga, han sido origen de múltiples controversias, debido a la dificultad planteada por su asignación estratigráfica y cronológica. Los numerosos análisis y revisiones suscitados por este yacimiento tanto de los materiales líticos y fauna, como de los restos craneales asignados a los niveles más antiguos (B1 al Magdaleniense; A1 y A2 al Aziliense nos indujeron a efectuar una datación de estos cráneos mediante las series de desintegración del Uranio (U/Th y U/Pa por espectrometría de rayos gamma y mediante el radioisótopo C14 por acelerador de partículas. Una valoración crítica de las dataciones, nos induce a signar estos cráneos a la Edad del Bronce, dados los valores ofrecidos por el C14 (cráneo A1: 3.430 ± 100 B.P. y sendas dataciones del cráneo B1: 3.475 ± 120 B.P. y 3.445 ± 110 B.P. Los datos que aquí aportamos sobre el yacimiento y los restos humanos de la cueva de Urtiaga, concuerdan con la existencia de una posible remoción en algunos sectores del yacimiento y consiguiente deslizamiento de materiales del Calcolítico y del Bronce a niveles más antiguos. Con ello creemos justificadas las reservas sobre la hipótesis del origen de las características antropológicas de las vascos actuales a partir de alguna forma del Paleolítico Superior, dada la penuria de restos que en la actualidad se conocen, para algunos períodos de nuestra prehistoria.

  5. CONNECTION OF THE NEO-TETHYAN OCEAN TO THE RISE OF ...

    Indian Academy of Sciences (India)

    Table of contents. CONNECTION OF THE NEO-TETHYAN OCEAN TO THE RISE OF THE HIMALAYAN MOUNTAIN BELT · Slide 2 · Slide 3 · Slide 4 · Slide 5 · Slide 6 · Slide 7 · Slide 8 · Slide 9 · Slide 10 · Slide 11 · LADAKH MAFIC MAGMATIC ROCKS (INDUS SUTURE ZONE) · Contrast in characteristics for the mafic ...

  6. Thermal surface analysis on high-rise building façades with neo-minimalist and modern style in Penang, Malaysia

    Science.gov (United States)

    Arab, Yasser; Hassan, Ahmad Sanusi; Qanaa, Bushra

    2017-10-01

    This research analyzed the façade thermal performance of high-rise buildings with modern and neo-minimalist architectural style. Four high-rise apartment buildings in Penang Island are selected as case studies for this research. The modern architectural style, which was popular during the 1970s to 1990s, nearly disregarded the cultural identity of the country and used the basic geometric shapes in the design. Conversely, the neo-minimalist style is the popular style from the 2010s up to the present. This style is a result of the "less is more" concept, which means using minimal applications to obtain an efficient design. The four selected case studies are as follows: Halaman Kristal 2 and Mutiara Idaman 1 with modern architectural style and Light Linear and Baystar apartments with neo-minimalist style. The research uses Fluke Ti20 thermal imager to capture thermal images of the west façade of the selected case studies on an hourly basis from 12:00 to 6:00 P.M. on March 15, 2017. Results confirm that the neo-minimalist façade elements, such as balconies and recessed walls, as well as other shading elements, are effective in improving the performance of façade shading. Notably, façade shading causes low surface temperature and provides cool indoor atmosphere during the day when the temperature is extremely high outside. Accordingly, this distinct feature partly explains the current popularity of the neo-minimalist architectural style.

  7. Alienation in Mathematics Education: Critique and Development of Neo-Vygotskian Perspectives

    Science.gov (United States)

    Williams, Julian

    2016-01-01

    This paper aims to critique and develop neo-Vygotskian work in mathematics education from (i) within the Vygotskian and activity theoretic tradition, and where necessary from (ii) a Bourdieusian perspective. First, I critique Roth and Radford's (2011) version of Cultural-historical Activity Theory, suggesting that a classroom episode presented as…

  8. Polymer electrolyte fuel cells physical principles of materials and operation

    CERN Document Server

    Eikerling, Michael

    2014-01-01

    The book provides a systematic and profound account of scientific challenges in fuel cell research. The introductory chapters bring readers up to date on the urgency and implications of the global energy challenge, the prospects of electrochemical energy conversion technologies, and the thermodynamic and electrochemical principles underlying the operation of polymer electrolyte fuel cells. The book then presents the scientific challenges in fuel cell research as a systematic account of distinct components, length scales, physicochemical processes, and scientific disciplines. The main part of t

  9. Violencias contra las mujeres negras: Neo conquista y neo colonización de territorios y cuerpos en la región del Pacífico colombiano

    Directory of Open Access Journals (Sweden)

    Betty Ruth Lozano Lerma

    2016-06-01

    Full Text Available En este ensayo cuestiono la apreciación generalizada por parte de funcionarios y funcionarias del Estado colombiano de que los asesinatos de mujeres que se suceden en número alarmante en los últimos 10 años en Buenaventura, no son más que violencia intrafamiliar y que la crueldad con la que son cometidos son solo expresión de prácticas culturales tradicionalmente violentas de las comunidades negras que allí habitan. Me pr0pongo probar que la violencia contra las mujeres es parte de la estrategia de desterritorialización de la población negra por parte del capitalismo global que necesita de esos territorios para la ejecución de sus megaproyectos de gran inversión. Planteo que lo que se vive hoy en la ciudad colombiana de Buenaventura es un proceso de neo conquista y neo colonización de los territorios, los cuerpos y los imaginarios de sus habitantes, las comunidades negras e indígenas.

  10. Presencia de deformación artificial en cráneos de la cultura de la Aguada

    Directory of Open Access Journals (Sweden)

    Kriscautzky, Néstor

    2003-01-01

    Full Text Available El objetivo del trabajo fue describir los diferentes tipos de deformación artificial presentes en cráneos de la cultura de La Aguada. Se analizaron....cráneos provenientes de excavaciones sistemáticas en los sitios...La muestra estudiada corresponde a ....individuos adultos,...subadultos y ....infantiles. Se observó deformación cefálica artificial en el ...% de la muestra, con dos patrones claramente definidos: tabular erecto y tabular oblicuo. La deformación está presente en ambos sexos y en todos los sitios estudiados.

  11. Prospect of Uranium Silicide fuel element with hypostoichiometric (Si ≤3.7%)

    International Nuclear Information System (INIS)

    Suripto, A.; Sardjono; Martoyo

    1996-01-01

    An attempt to obtain high uranium-loading in silicide dispersion fuel element using the fabrication technology applicable nowadays can reach Uranium-loading slightly above 5 gU/cm 3 . It is difficult to achieve a higher uranium-loading than that because of fabricability constraints. To overcome those difficulties, the use of uranium silicide U 3 Si based is considered. The excess of U is obtained by synthesising U 3 Si 2 in Si-hypostoichiometric stage, without applying heat treatment to the ingot as it can generate undesired U 3 Si. The U U will react with the matrix to form U al x compound, that its pressure is tolerable. This experiment is to consider possibilities of employing the U 3 Si 2 as nuclear fuel element which have been performed by synthesising U 3 Si 2 -U with the composition of 3.7 % weigh and 3 % weigh U. The ingot was obtained and converted into powder form which then was fabricated into experimental plate nuclear fuel element. The interaction between free U and Al-matrix during heat-treatment is the rolling phase of the fuel element was observed. The study of the next phase will be conducted later

  12. The Netherlands Epidemiology of Obesity (NEO) study: study design and data collection

    NARCIS (Netherlands)

    de Mutsert, R.; den Heijer, M.; Rabelink, T.J.; Smit, J.W.A.; Romijn, J.A.; Jukema, J.W.; de Roos, A.; Cobbaert, C.M.; Kloppenburg, M.; Le Cessie, S.; Middeldorp, S.; Rosendaal, F.R.

    2013-01-01

    Obesity is a well-established risk factor for many chronic diseases. Incomplete insight exists in the causal pathways responsible for obesity-related disorders and consequently, in the identification of obese individuals at risk of these disorders. The Netherlands Epidemiology of Obesity (NEO) study

  13. Prospects of pyrolysis oil from plastic waste as fuel for diesel engines: A review

    Science.gov (United States)

    Mangesh, V. L.; Padmanabhan, S.; Ganesan, S.; PrabhudevRahul, D.; Reddy, T. Dinesh Kumar

    2017-05-01

    The purpose ofthis study is to review the existing literature about chemical recycling of plastic waste and its potential as fuel for diesel engines. This is a review covering on the field of converting waste plastics into liquid hydrocarbon fuels for diesel engines. Disposal and recycling of waste plastics have become an incremental problem and environmental threat with increasing demand for plastics. One of the effective measures is by converting waste plastic into combustible hydrocarbon liquid as an alternative fuel for running diesel engines. Continued research efforts have been taken by researchers to convert waste plastic in to combustible pyrolysis oil as alternate fuel for diesel engines. An existing literature focuses on the study of chemical structure of the waste plastic pyrolysis compared with diesel oil. Converting waste plastics into fuel oil by different catalysts in catalytic pyrolysis process also reviewed in this paper. The methodology with subsequent hydro treating and hydrocracking of waste plastic pyrolysis oil can reduce unsaturated hydrocarbon bonds which would improve the combustion performance in diesel engines as an alternate fuel.

  14. Romanian nuclear fuel program

    International Nuclear Information System (INIS)

    Budan, O.

    1999-01-01

    of January 1997 with fuel produced by the Romanian fuel plant. The quality evaluation of the 'pre-1990' fuel started in April 1996 and was performed by the Nuclear Fuel Plant (FCN) Pitesti, under the supervision of the Nuclear Power Group (GEN) - a distinct department of RENEL. The paper presents the involvement of Romania in the activities related to the Advanced CANDU Fuel Cycle. The future prospect and trend of the Romanian Nuclear Fuel Program are also presented in this paper. (author)

  15. The discovery of the periodic table as a case of simultaneous discovery.

    Science.gov (United States)

    Scerri, Eric

    2015-03-13

    The article examines the question of priority and simultaneous discovery in the context of the discovery of the periodic system. It is argued that rather than being anomalous, simultaneous discovery is the rule. Moreover, I argue that the discovery of the periodic system by at least six authors in over a period of 7 years represents one of the best examples of a multiple discovery. This notion is supported by a new view of the evolutionary development of science through a mechanism that is dubbed Sci-Gaia by analogy with Lovelock's Gaia hypothesis. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

  16. Final Report - Low Temperature Combustion Chemistry And Fuel Component Interactions

    Energy Technology Data Exchange (ETDEWEB)

    Wooldridge, Margaret [Univ. of Michigan, Ann Arbor, MI (United States)

    2017-02-24

    Recent research into combustion chemistry has shown that reactions at “low temperatures” (700 – 1100 K) have a dramatic influence on ignition and combustion of fuels in virtually every practical combustion system. A powerful class of laboratory-scale experimental facilities that can focus on fuel chemistry in this temperature range is the rapid compression facility (RCF), which has proven to be a versatile tool to examine the details of fuel chemistry in this important regime. An RCF was used in this project to advance our understanding of low temperature chemistry of important fuel compounds. We show how factors including fuel molecular structure, the presence of unsaturated C=C bonds, and the presence of alkyl ester groups influence fuel auto-ignition and produce variable amounts of negative temperature coefficient behavior of fuel ignition. We report new discoveries of synergistic ignition interactions between alkane and alcohol fuels, with both experimental and kinetic modeling studies of these complex interactions. The results of this project quantify the effects of molecular structure on combustion chemistry including carbon bond saturation, through low temperature experimental studies of esters, alkanes, alkenes, and alcohols.

  17. Adaptivní administrace NEO PI-R: Výhody a omezení

    Czech Academy of Sciences Publication Activity Database

    Jelínek, Martin; Květon, Petr; Vobořil, Dalibor

    2011-01-01

    Roč. 55, č. 1 (2011), s. 69-81 ISSN 0009-062X R&D Projects: GA ČR GP406/09/P284 Institutional research plan: CEZ:AV0Z70250504 Keywords : adaptive testing * item response theory * NEO PI-R * CATo Subject RIV: AN - Psychology Impact factor: 0.087, year: 2011

  18. A Neo-Aristotelian Account of Education, Justice, and the Human Good

    Science.gov (United States)

    Curren, Randall

    2013-01-01

    This article sketches the contours of a neo-Aristotelian account of education, justice, and the human good, organized around a sequence of three increasingly distinctive features of the Aristotelian understanding of respect for persons as rational beings. The first and second of these features bear on important aspects of educational justice,…

  19. La autonomía: principio ético contemporáneo

    Directory of Open Access Journals (Sweden)

    Héctor Mauricio Mazo Álvarez

    2012-01-01

    Full Text Available La historia de la humanidad fue testigo, en la segunda mitad del siglo XX, de un evento fundamental que permite entender muchas de las manifestaciones, ideologías, creencias y valores que han surgido en el mundo contemporáneo: el profun- do desencanto en el que se ve envuelta la sociedad, surgido después de la Segunda Guerra Mundial, y que obligó a los hombres a repensar el mundo en el que vivían y a generar un nuevo modo de relación con ellos mismos y con los demás. Este proceso ha sido arduo y no ha culminado; incluye la proclamación de derechos humanos, la conquista de derechos civiles y el reconocimiento de los grupos minoritarios y de las poblaciones vulnerables. Para ello, el establecimiento de unos principios en términos éticos se ha vuelto fundamental; específicamente, el principio de la autonomía como base de los sistemas éticos y filosóficos del mundo contemporáneo ha cobrado especial relevancia. © Revista Colombiana de Ciencias Sociales.

  20. New neo-Clerodanes from Tinnea antiscorbutica Welv

    International Nuclear Information System (INIS)

    Borges, Cristina M.P.; Mendonca, Dina I.M.D. de; Pinheiro, Sandra C.S.; Vieira, Liliana; Mendonca, Antonio J.G.; Gaspar, Jorge F.; Martins, Celia; Rueff, Jose; Diakanawma, Carlos

    2013-01-01

    Three new neo-clerodanes, antiscorbuticane A, antiscorbuticane B and antiscorbuticane C, and known compounds glutinol, friedelin, 5,7-dihydroxyflavanone (pinocembrin), 5-hydroxy-3,6,7,4'- tetramethoxyflavone, 5-hydroxy-3,6,7,3'4'-pentamethoxyflavone (artemetin), 5,4’-dihydroxy-3,6,7,3'-tetramethoxyflavone (penduletin) and 5,3',4'-trihydroxy-3,6,7-trimethoxyflavone (chrysosplenol D), were isolated from the methanol extract of Tinnea antiscorbutica. Antiscorbuticane B exhibited no mutagenic activity at doses of up to 250 μg per plate (Ames test) and did not induce micronucleus formation in the V79 cell line at doses of up to 100 μg mL -1 . (author)

  1. Transportation and packaging issues involving the disposition of surplus plutonium as MOX fuel in commercial LWRs

    International Nuclear Information System (INIS)

    Ludwig, S.B.; Welch, D.E.; Best, R.E.; Schmid, S.P.

    1997-08-01

    This report provides a view of anticipated transportation, packaging, and facility handling operations that are expected to occur at mixed-oxide (MOX) fuel fabrication and commercial reactor facilities. This information is intended for use by prospective contractors to the U.S. Department of Energy (DOE) who plan to submit proposals to DOE to manufacture and irradiate MOX fuel assemblies in domestic commercial light-water reactors. The report provides data to prospective consortia regarding packaging and pickup of MOX nuclear fuel assemblies at a MOX fuel manufacturing plant and transport and delivery of the MOX assemblies to nuclear power plants. The report also identifies areas where data are incomplete either because of the status of development or lack of sufficient information and specificity regarding the nuclear power plant(s) where deliveries will take place

  2. "Eureka, Eureka!" Discoveries in Science

    Science.gov (United States)

    Agarwal, Pankaj

    2011-01-01

    Accidental discoveries have been of significant value in the progress of science. Although accidental discoveries are more common in pharmacology and chemistry, other branches of science have also benefited from such discoveries. While most discoveries are the result of persistent research, famous accidental discoveries provide a fascinating…

  3. Safe disposal of research reactor RA spent fuel-activities, problems and prospects

    International Nuclear Information System (INIS)

    Matausek, M.V.; Vukadin, Z.; Plecas, I.; Pavlovic, R.; Sotic, O.; Bulkin, S.; Sokolov, A.; Morduhai, A.

    2001-01-01

    In order to improve conditions in the existing temporary spent fuel storage pool, technology was elaborated and equipment was produced and applied for removal of sludge and other debris from the bottom of the pool, filtration of the pool water, sludge conditioning in cement matrix and disposal at the low and medium waste repository at Vinca site. Safety measures and precautions were determined. Subcriticality was proved under normal and/or possible abnormal conditions. In the frame of the joint Yugoslav-Russian project, the technology has been developed and the equipment has been manufactured, tested and applied for underwater inspection the state of spent fuel inside the aluminum barrels. Based on the results of this inspection, a procedure will be proposed for transferring spent fuel to a more reliable storage facility. (author)

  4. Big Data in Drug Discovery.

    Science.gov (United States)

    Brown, Nathan; Cambruzzi, Jean; Cox, Peter J; Davies, Mark; Dunbar, James; Plumbley, Dean; Sellwood, Matthew A; Sim, Aaron; Williams-Jones, Bryn I; Zwierzyna, Magdalena; Sheppard, David W

    2018-01-01

    Interpretation of Big Data in the drug discovery community should enhance project timelines and reduce clinical attrition through improved early decision making. The issues we encounter start with the sheer volume of data and how we first ingest it before building an infrastructure to house it to make use of the data in an efficient and productive way. There are many problems associated with the data itself including general reproducibility, but often, it is the context surrounding an experiment that is critical to success. Help, in the form of artificial intelligence (AI), is required to understand and translate the context. On the back of natural language processing pipelines, AI is also used to prospectively generate new hypotheses by linking data together. We explain Big Data from the context of biology, chemistry and clinical trials, showcasing some of the impressive public domain sources and initiatives now available for interrogation. © 2018 Elsevier B.V. All rights reserved.

  5. The industrial nuclear fuel cycle in Argentina

    International Nuclear Information System (INIS)

    Koll, J.H.; Kittl, J.E.; Parera, C.A.; Coppa, R.C.; Aguirre, E.J.

    1977-01-01

    The nuclear power program of Argentina for the period 1976-85 is described, as a basis to indicate fuel requirements and the consequent implementation of a national fuel cycle industry. Fuel cycle activities in Argentina were initiated as soon as 1951-2 in the prospection and mining activities through the country. Following this step, yellow-cake production was initiated in plants of limited capacity. National production of uranium concentrate has met requirements up to the present time, and will continue to do so until the Sierra Pintada Industrial Complex starts operation in 1979. Presently, there is a gap in local production of uranium dioxide and fuel elements for the Atucha power station, which are produced abroad using Argentine uranium concentrate. With its background, the argentine program for the installation of nuclear fuel cycle industries is described, and the techno-economical implications considered. Individual projects are reviewed, as well as the present and planned infrastructure needed to support the industrial effort [es

  6. Particulate Study on NeoProfen, a Neonatal Injectable Product.

    Science.gov (United States)

    Krishna, Aravind; Rice, Michael; Kester, Tom; Waters, Michael; Wilson, Terry

    2016-01-01

    NeoProfen or sterile ibuprofen L-lysine at 10 mg/mL ibuprofen, in 2 mL single-use Type I glass vials is often a first choice medication used to close a patent ductus arteriosus in neonatal patients from 500 to 1500 g body weight. Visible particulate matter was found in vials that were placed on a commercial stability program prior to the approved expiration date of 2 years. A combination of instrumental techniques including inductively coupled plasma-mass spectrometry, x-ray photoelectron spectroscopy, scanning electron microscopy energy dispersive x-ray spectrometry, and Raman and Fourier transform infrared microspectroscopy was used to evaluate stability, pilot batch and packaging samples in a root cause investigation. The particulate matter was shown to consist largely of ibuprofen aluminum salts of various stoichiometries. It developed over time by a substitution mechanism, in which the ibuprofen anion in solution reacts with the aluminum oxide network of the borosilicate glass giving the ibuprofen aluminum salt with =Al-OH remaining in the network. For corrective action an alternate Type I borosilicate glass vial with interior coating, not found in the original vial, was chosen for the product to prevent this occurrence. NeoProfen (sterile preservative-free ibuprofin L-lysine at 17 mg/mL in a single-use glass vial) is used to close a clinically significant patent ductus arteriosus in premature infants no more than 32 weeks gestational age. The neonatal population is especially sensitive to outside chemical, physical and environmental conditions because of incompletely developed organ systems, low birth weight and other underlying conditions. Two batches of this product were voluntarily recalled by the manufacturer, Lundbeck, and investigated for the source of particulate matter observed during a commercial stability testing program. This was found to result from an interaction between the product and the Type I borosilicate glass vial where ibuprofen

  7. 30 CFR 44.24 - Discovery.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Discovery. 44.24 Section 44.24 Mineral... Discovery. Parties shall be governed in their conduct of discovery by appropriate provisions of the Federal... discovery. Alternative periods of time for discovery may be prescribed by the presiding administrative law...

  8. 19 CFR 356.20 - Discovery.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Discovery. 356.20 Section 356.20 Customs Duties... § 356.20 Discovery. (a) Voluntary discovery. All parties are encouraged to engage in voluntary discovery... sanctions proceeding. (b) Limitations on discovery. The administrative law judge shall place such limits...

  9. Chemical Discovery

    Science.gov (United States)

    Brown, Herbert C.

    1974-01-01

    The role of discovery in the advance of the science of chemistry and the factors that are currently operating to handicap that function are considered. Examples are drawn from the author's work with boranes. The thesis that exploratory research and discovery should be encouraged is stressed. (DT)

  10. Recon2Neo4j: applying graph database technologies for managing comprehensive genome-scale networks.

    Science.gov (United States)

    Balaur, Irina; Mazein, Alexander; Saqi, Mansoor; Lysenko, Artem; Rawlings, Christopher J; Auffray, Charles

    2017-04-01

    The goal of this work is to offer a computational framework for exploring data from the Recon2 human metabolic reconstruction model. Advanced user access features have been developed using the Neo4j graph database technology and this paper describes key features such as efficient management of the network data, examples of the network querying for addressing particular tasks, and how query results are converted back to the Systems Biology Markup Language (SBML) standard format. The Neo4j-based metabolic framework facilitates exploration of highly connected and comprehensive human metabolic data and identification of metabolic subnetworks of interest. A Java-based parser component has been developed to convert query results (available in the JSON format) into SBML and SIF formats in order to facilitate further results exploration, enhancement or network sharing. The Neo4j-based metabolic framework is freely available from: https://diseaseknowledgebase.etriks.org/metabolic/browser/ . The java code files developed for this work are available from the following url: https://github.com/ibalaur/MetabolicFramework . ibalaur@eisbm.org. Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press.

  11. Industrial integration of the fuel cycle in Argentina

    International Nuclear Information System (INIS)

    Koll, J.H.; Kittl, J.E.; Parera, C.A.; Coppa, R.C.; Aguirre, E.J.

    1983-01-01

    The power-reactor construction program in Argentina for the period 1976-1985 is described on the basis of which the nuclear-fuel requirements have been determined. Activities connected with the fuel cycle commenced in 1950 in Argentina with the prospection and working of uranium deposits. On the basis of the nuclear power program described, plans have been drawn up for the establishment of the industrial plants that will be needed to ensure the domestic supply of fuel. The demand for fuel is correlated with the availability of uranium resoures and it is shown to be desirable from the technical, economic and industrial point of view to integrate the front end of the fuel cycle, keeping the irradiation aspects and the tail end at the development level. Progress made in this field and current programs covering exploration, concentrate production, nuclear purification, conversion to uranium dioxide, production of special alloys and fuel element fabrication are described

  12. Seven years of NeoBiota – the times, were they a changin’?

    Czech Academy of Sciences Publication Activity Database

    Kühn, I.; Pyšek, Petr; Kowarik, I.

    2017-01-01

    Roč. 36, č. 1 (2017), s. 57-69 ISSN 1619-0033 Grant - others:AV ČR(CZ) AP1002 Program:Akademická prémie - Praemium Academiae Institutional support: RVO:67985939 Keywords : NeoBiota * journal * history Subject RIV: EH - Ecology, Behaviour OBOR OECD: Ecology

  13. Status and prospects of thermal breeders and their effect on fuel utilization

    Energy Technology Data Exchange (ETDEWEB)

    1979-01-01

    The report evaluates the extent to which thermal breeders and near-breeders might complement fast breeders or serve as an alternative in solving the long-term nuclear fuel supply problem. It considers in a general way issues such as proliferation, safety, environmental impacts, economics, power plant availability and fuel cycle versatility in order to determine whether thermal breeder reactors offer advantages or disadvantages with respect to such issues.

  14. Status and prospects of thermal breeders and their effect on fuel utilization

    International Nuclear Information System (INIS)

    1979-01-01

    The report evaluates the extent to which thermal breeders and near-breeders might complement fast breeders or serve as an alternative in solving the long-term nuclear fuel supply problem. It considers in a general way issues such as proliferation, safety, environmental impacts, economics, power plant availability and fuel cycle versatility in order to determine whether thermal breeder reactors offer advantages or disadvantages with respect to such issues

  15. 24 CFR 180.500 - Discovery.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Discovery. 180.500 Section 180.500... OPPORTUNITY CONSOLIDATED HUD HEARING PROCEDURES FOR CIVIL RIGHTS MATTERS Discovery § 180.500 Discovery. (a) In general. This subpart governs discovery in aid of administrative proceedings under this part. Discovery in...

  16. 22 CFR 224.21 - Discovery.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Discovery. 224.21 Section 224.21 Foreign....21 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of... parties, discovery is available only as ordered by the ALJ. The ALJ shall regulate the timing of discovery...

  17. Prospects for SUSY discovery based on inclusive searches with the ATLAS detector

    International Nuclear Information System (INIS)

    Ventura, Andrea

    2009-01-01

    The search for Supersymmetry (SUSY) among the possible scenarios of new physics is one of the most relevant goals of the ATLAS experiment running at CERN's Large Hadron Collider. In the present work the expected prospects for discovering SUSY with the ATLAS detector are reviewed, in particular for the first fb -1 of collected integrated luminosity. All studies and results reported here are based on inclusive search analyses realized with Monte Carlo signal and background data simulated through the ATLAS apparatus.

  18. Liquid-fueled SOFC power sources for transportation

    Science.gov (United States)

    Myles, K. M.; Doshi, R.; Kumar, R.; Krumpelt, M.

    Traditionally, fuel cells have been developed for space or stationary terrestrial applications. As the first commercial 200-kW systems were being introduced by ONSI and Fuji Electric, the potentially much larger, but also more challenging, application in transportation was beginning to be addressed. As a result, fuel cell-powered buses have been designed and built, and R&D programs for fuel cell-powered passenger cars have been initiated. The engineering challenge of eventually replacing the internal combustion engine in buses, trucks, and passenger cars with fuel cell systems is to achieve much higher power densities and much lower costs than obtainable in systems designed for stationary applications. At present, the leading fuel cell candidate for transportation applications is, without question, the polymer electrolyte fuel cell (PEFC). Offering ambient temperature start-up and the potential for a relatively high power density, the polymer technology has attracted the interest of automotive manufacturers worldwide. But the difficulties of fuel handling for the PEFC have led to a growing interest in exploring the prospects for solid oxide fuel cells (SOFCs) operating on liquid fuels for transportation applications. Solid oxide fuel cells are much more compatible with liquid fuels (methanol or other hydrocarbons) and are potentially capable of power densities high enough for vehicular use. Two SOFC options for such use are discussed in this report.

  19. Prospect and problems of self-supporting nuclear fuel cycle operation in Korea beyond the year 2000

    International Nuclear Information System (INIS)

    Kim, Chang Hyo

    1988-01-01

    Korea ranks tenth in the free world in the installed capacity of nuclear power plants. Since she lacks in indigenous uranium resources and built-in domestic fuel cycle technology, however, she had to rely heavily upon overseas uranium markets and fuel cycle services. Despite the fact that localization of fuel fabrication technology is nearly achieved, such issues as the timely and stable procurement of front-end fuel cycle services including uranium ore, interim storage and ultimate fuel cycle services including uranium ore, interim storage and ultimate disposal of ever-accumulating spent fuels, disposal of radioactive waste, and decommissioning of the retiring nuclear power plants has yet fuel cycle technology beyond the year 2000. The purpose of this report is to identify these issues of fuel cycle operation and to suggest mobilizing nation's research potential for establishing self-reliant fuel cycle technology beyond the year 2000

  20. 19 CFR 207.109 - Discovery.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Discovery. 207.109 Section 207.109 Customs Duties... and Committee Proceedings § 207.109 Discovery. (a) Discovery methods. All parties may obtain discovery under such terms and limitations as the administrative law judge may order. Discovery may be by one or...